ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0030695	GTPase regulator activity	238/5317	489/18639	0.486707566462168	1.70617685373112	1.22318614366511e-21	1.17998003234239e-18
GO:0060589	nucleoside-triphosphatase regulator activity	238/5317	490/18639	0.485714285714286	1.70269486015207	1.71758374431206e-21	1.17998003234239e-18
GO:0005096	GTPase activator activity	138/5317	271/18639	0.509225092250922	1.78511312666258	4.59617840602737e-15	2.10504970996053e-12
GO:0005085	guanyl-nucleotide exchange factor activity	116/5317	230/18639	0.504347826086956	1.76801563483821	1.58102746537921e-12	5.4308293435776e-10
GO:0003779	actin binding	188/5317	443/18639	0.424379232505643	1.48768187223485	1.70135148428724e-10	4.67531387882135e-08
GO:0005201	extracellular matrix structural constituent	86/5317	168/18639	0.511904761904762	1.79450683790537	4.46905841865695e-10	1.02341437787244e-07
GO:0019838	growth factor binding	71/5317	136/18639	0.522058823529412	1.83010239077764	4.89932615855833e-09	9.61667734551306e-07
GO:0031267	small GTPase binding	125/5317	283/18639	0.441696113074205	1.54838703246005	1.18734715667897e-08	2.03926874159613e-06
GO:0005178	integrin binding	79/5317	161/18639	0.490683229813665	1.72011373340171	2.61046592538211e-08	3.98531131275001e-06
GO:0005516	calmodulin binding	96/5317	207/18639	0.463768115942029	1.62576150329951	3.27844871365225e-08	4.50458853255819e-06
GO:0141003	histone H2AX kinase activity	148/5317	354/18639	0.418079096045198	1.46559643994479	4.64059721345252e-08	5.79652779207615e-06
GO:0004674	protein serine/threonine kinase activity	175/5317	433/18639	0.404157043879908	1.41679201445883	5.20268153037533e-08	5.95707035227975e-06
GO:0017124	SH3 domain binding	60/5317	115/18639	0.521739130434783	1.82898169121195	7.62327703445235e-08	7.67200516798002e-06
GO:0140996	histone H3 kinase activity	148/5317	357/18639	0.414565826330532	1.45328050347466	8.7337624615181e-08	7.67200516798002e-06
GO:0003712	transcription coregulator activity	195/5317	495/18639	0.393939393939394	1.38097354967771	8.8441608226604e-08	7.67200516798002e-06
GO:0035173	histone kinase activity	149/5317	360/18639	0.413888888888889	1.45090746661651	8.93392159298983e-08	7.67200516798002e-06
GO:0051020	GTPase binding	133/5317	315/18639	0.422222222222222	1.48012036862893	1.10972150863324e-07	8.96916089918864e-06
GO:0005543	phospholipid binding	195/5317	497/18639	0.392354124748491	1.37541631205325	1.2475671790118e-07	9.5230961331234e-06
GO:0140297	DNA-binding transcription factor binding	190/5317	488/18639	0.389344262295082	1.36486509402258	3.38721663397415e-07	2.44949245004236e-05
GO:0106310	protein serine kinase activity	146/5317	361/18639	0.404432132963989	1.41775635251378	6.17784568112734e-07	4.24417998293448e-05
GO:0004713	protein tyrosine kinase activity	67/5317	140/18639	0.478571428571429	1.67765522985572	9.23575167272481e-07	6.04282038015423e-05
GO:0035091	phosphatidylinositol binding	118/5317	284/18639	0.415492957746479	1.45653060737947	1.49561633131671e-06	9.34080381467799e-05
GO:0008013	beta-catenin binding	53/5317	106/18639	0.5	1.75277412074478	2.37369149064222e-06	0.000141802265571409
GO:0045296	cadherin binding	134/5317	334/18639	0.401197604790419	1.40641755796288	2.90754733356375e-06	0.000166457084846525
GO:0005539	glycosaminoglycan binding	102/5317	242/18639	0.421487603305785	1.47754512657824	3.51050546916441e-06	0.000192937380585276
GO:0008201	heparin binding	77/5317	172/18639	0.447674418604651	1.5693442708994	3.8619515948237e-06	0.000204089288126453
GO:0050840	extracellular matrix binding	37/5317	67/18639	0.552238805970149	1.93589977515095	4.06857866727035e-06	0.000207045447734425
GO:0019199	transmembrane receptor protein kinase activity	41/5317	78/18639	0.525641025641026	1.84265997309067	6.63389948261627e-06	0.000325534924611241
GO:0035401	histone H3Y41 kinase activity	55/5317	115/18639	0.478260869565217	1.67656655027762	8.63305123768961e-06	0.000395393746686184
GO:0140801	histone H2AXY142 kinase activity	55/5317	115/18639	0.478260869565217	1.67656655027762	8.63305123768961e-06	0.000395393746686184
GO:0019955	cytokine binding	65/5317	144/18639	0.451388888888889	1.58236552567237	1.53082216765437e-05	0.000678499889792615
GO:0004896	cytokine receptor activity	47/5317	96/18639	0.489583333333333	1.71625799322926	1.76651333564997e-05	0.000758496663494705
GO:0003714	transcription corepressor activity	86/5317	204/18639	0.42156862745098	1.47782916062795	1.95242667846699e-05	0.000760696740434533
GO:0140375	immune receptor activity	69/5317	156/18639	0.442307692307692	1.55053095296654	1.95946456731592e-05	0.000760696740434533
GO:0005112	Notch binding	18/5317	26/18639	0.692307692307692	2.42691801333893	1.96070679002614e-05	0.000760696740434533
GO:0042578	phosphoric ester hydrolase activity	140/5317	363/18639	0.385674931129477	1.35200207660754	1.99309189633502e-05	0.000760696740434533
GO:0005030	neurotrophin receptor activity	29/5317	51/18639	0.568627450980392	1.99335096084701	2.09048987118402e-05	0.000776306238650499
GO:0015631	tubulin binding	147/5317	385/18639	0.381818181818182	1.33848205584147	2.29365490572798e-05	0.000827896633300061
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	135/5317	349/18639	0.386819484240688	1.35601436275384	2.34992494168139e-05	0.000827896633300061
GO:0045309	protein phosphorylated amino acid binding	32/5317	59/18639	0.542372881355932	1.90131430046891	2.93372602046562e-05	0.00100773488802994
GO:0001784	phosphotyrosine residue binding	27/5317	47/18639	0.574468085106383	2.01382558553656	3.12173453025138e-05	0.00104616176696717
GO:0003713	transcription coactivator activity	103/5317	256/18639	0.40234375	1.41043542528682	3.37794343577017e-05	0.00110507006684481
GO:0051219	phosphoprotein binding	45/5317	93/18639	0.483870967741935	1.69623302007559	3.82661008563577e-05	0.00122273540875896
GO:0019902	phosphatase binding	80/5317	190/18639	0.421052631578947	1.47602031220613	3.93357651081981e-05	0.00122834866496964
GO:0005006	epidermal growth factor receptor activity	28/5317	50/18639	0.56	1.96310701523415	4.23304308806497e-05	0.00123267942556335
GO:0005017	platelet-derived growth factor receptor activity	28/5317	50/18639	0.56	1.96310701523415	4.23304308806497e-05	0.00123267942556335
GO:0005019	platelet-derived growth factor beta-receptor activity	28/5317	50/18639	0.56	1.96310701523415	4.23304308806497e-05	0.00123267942556335
GO:0031994	insulin-like growth factor I binding	11/5317	13/18639	0.846153846153846	2.96623312741424	4.3063036700903e-05	0.00123267942556335
GO:0005158	insulin receptor binding	16/5317	23/18639	0.695652173913043	2.43864225494926	5.28012545529878e-05	0.00148059028073072
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	13/5317	17/18639	0.764705882352941	2.68071336113908	5.73364660581524e-05	0.00154471185027258
GO:0019198	transmembrane receptor protein phosphatase activity	13/5317	17/18639	0.764705882352941	2.68071336113908	5.73364660581524e-05	0.00154471185027258
GO:0005010	insulin-like growth factor receptor activity	28/5317	51/18639	0.549019607843137	1.9246147208178	6.84136874339824e-05	0.00180770012565946
GO:0005004	GPI-linked ephrin receptor activity	27/5317	49/18639	0.551020408163265	1.9316286228616	8.44923140171636e-05	0.0018395108116197
GO:0005008	hepatocyte growth factor receptor activity	27/5317	49/18639	0.551020408163265	1.9316286228616	8.44923140171636e-05	0.0018395108116197
GO:0005009	insulin receptor activity	27/5317	49/18639	0.551020408163265	1.9316286228616	8.44923140171636e-05	0.0018395108116197
GO:0005011	macrophage colony-stimulating factor receptor activity	27/5317	49/18639	0.551020408163265	1.9316286228616	8.44923140171636e-05	0.0018395108116197
GO:0005018	platelet-derived growth factor alpha-receptor activity	27/5317	49/18639	0.551020408163265	1.9316286228616	8.44923140171636e-05	0.0018395108116197
GO:0005020	stem cell factor receptor activity	27/5317	49/18639	0.551020408163265	1.9316286228616	8.44923140171636e-05	0.0018395108116197
GO:0008288	boss receptor activity	27/5317	49/18639	0.551020408163265	1.9316286228616	8.44923140171636e-05	0.0018395108116197
GO:0036332	placental growth factor receptor activity	27/5317	49/18639	0.551020408163265	1.9316286228616	8.44923140171636e-05	0.0018395108116197
GO:0038062	protein tyrosine kinase collagen receptor activity	27/5317	49/18639	0.551020408163265	1.9316286228616	8.44923140171636e-05	0.0018395108116197
GO:0060175	brain-derived neurotrophic factor receptor activity	27/5317	49/18639	0.551020408163265	1.9316286228616	8.44923140171636e-05	0.0018395108116197
GO:0008017	microtubule binding	108/5317	276/18639	0.391304347826087	1.37173626840896	8.57404930626012e-05	0.0018395108116197
GO:1901981	phosphatidylinositol phosphate binding	77/5317	185/18639	0.416216216216216	1.4590660248362	8.61286993235025e-05	0.0018395108116197
GO:0004879	nuclear receptor activity	31/5317	59/18639	0.525423728813559	1.84189822857926	8.70219816268415e-05	0.0018395108116197
GO:0016922	nuclear receptor binding	60/5317	137/18639	0.437956204379562	1.53527660211222	9.32401162069404e-05	0.00194108969194449
GO:0043548	phosphatidylinositol 3-kinase binding	17/5317	26/18639	0.653846153846154	2.2920892348201	0.000102123402394235	0.00209429186402506
GO:0071889	14-3-3 protein binding	20/5317	33/18639	0.606060606060606	2.12457469181186	0.000120010290017082	0.00242491380122752
GO:0098531	ligand-modulated transcription factor activity	31/5317	60/18639	0.516666666666667	1.81119992476961	0.000131141875625176	0.00261143387114481
GO:0005007	fibroblast growth factor receptor activity	27/5317	50/18639	0.54	1.89299605040436	0.000133986698568724	0.00262996748333466
GO:0016791	phosphatase activity	106/5317	273/18639	0.388278388278388	1.36112862123771	0.000141343362516039	0.00273529267742306
GO:0051015	actin filament binding	84/5317	209/18639	0.401913875598086	1.40892847983313	0.000177924336324977	0.00339538941820165
GO:0015026	coreceptor activity	31/5317	61/18639	0.508196721311475	1.7815081227242	0.000194276140216366	0.0036122487428608
GO:0004679	AMP-activated protein kinase activity	97/5317	248/18639	0.391129032258065	1.37112169122777	0.000194546147723216	0.0036122487428608
GO:0005044	scavenger receptor activity	17/5317	27/18639	0.62962962962963	2.20719704093787	0.000202457466430181	0.00370902078500092
GO:0005021	vascular endothelial growth factor receptor activity	27/5317	51/18639	0.529411764705882	1.85587848078859	0.000207756336095307	0.00375601586572305
GO:0140857	histone H3T45 kinase activity	96/5317	246/18639	0.390243902439024	1.36801882594715	0.000229965418913411	0.00410353877385749
GO:0016500	protein-hormone receptor activity	33/5317	67/18639	0.492537313432836	1.72661331297247	0.000261779356593689	0.00445306577547199
GO:0030165	PDZ domain binding	39/5317	83/18639	0.469879518072289	1.64718531829028	0.000266589202284206	0.00445306577547199
GO:0016849	phosphorus-oxygen lyase activity	15/5317	23/18639	0.652173913043478	2.28622711401493	0.000276009268365502	0.00445306577547199
GO:0019207	kinase regulator activity	109/5317	287/18639	0.379790940766551	1.33137546453785	0.000310456152803496	0.00445306577547199
GO:0001216	DNA-binding transcription activator activity	175/5317	491/18639	0.356415478615071	1.24943165429872	0.000311529934264732	0.00445306577547199
GO:0004676	3-phosphoinositide-dependent protein kinase activity	95/5317	245/18639	0.387755102040816	1.35929421608779	0.000320854084258899	0.00445306577547199
GO:0004711	ribosomal protein S6 kinase activity	95/5317	245/18639	0.387755102040816	1.35929421608779	0.000320854084258899	0.00445306577547199
GO:0035175	histone H3S10 kinase activity	95/5317	245/18639	0.387755102040816	1.35929421608779	0.000320854084258899	0.00445306577547199
GO:0035979	histone H2AXS139 kinase activity	95/5317	245/18639	0.387755102040816	1.35929421608779	0.000320854084258899	0.00445306577547199
GO:0044022	histone H3S28 kinase activity	95/5317	245/18639	0.387755102040816	1.35929421608779	0.000320854084258899	0.00445306577547199
GO:0044023	histone H4S1 kinase activity	95/5317	245/18639	0.387755102040816	1.35929421608779	0.000320854084258899	0.00445306577547199
GO:0044024	histone H2AS1 kinase activity	95/5317	245/18639	0.387755102040816	1.35929421608779	0.000320854084258899	0.00445306577547199
GO:0044025	histone H2BS14 kinase activity	95/5317	245/18639	0.387755102040816	1.35929421608779	0.000320854084258899	0.00445306577547199
GO:0072354	histone H3T3 kinase activity	95/5317	245/18639	0.387755102040816	1.35929421608779	0.000320854084258899	0.00445306577547199
GO:0072371	histone H2AS121 kinase activity	95/5317	245/18639	0.387755102040816	1.35929421608779	0.000320854084258899	0.00445306577547199
GO:0072518	Rho-dependent protein serine/threonine kinase activity	95/5317	245/18639	0.387755102040816	1.35929421608779	0.000320854084258899	0.00445306577547199
GO:0140823	histone H2BS36 kinase activity	95/5317	245/18639	0.387755102040816	1.35929421608779	0.000320854084258899	0.00445306577547199
GO:0140855	histone H3S57 kinase activity	95/5317	245/18639	0.387755102040816	1.35929421608779	0.000320854084258899	0.00445306577547199
GO:0140995	histone H2A kinase activity	95/5317	245/18639	0.387755102040816	1.35929421608779	0.000320854084258899	0.00445306577547199
GO:0140997	histone H4 kinase activity	95/5317	245/18639	0.387755102040816	1.35929421608779	0.000320854084258899	0.00445306577547199
GO:0140998	histone H2B kinase activity	95/5317	245/18639	0.387755102040816	1.35929421608779	0.000320854084258899	0.00445306577547199
GO:1990244	histone H2AT120 kinase activity	95/5317	245/18639	0.387755102040816	1.35929421608779	0.000320854084258899	0.00445306577547199
GO:0038024	cargo receptor activity	32/5317	65/18639	0.492307692307692	1.72580836504101	0.000326097942632771	0.00448058573177427
GO:0004714	transmembrane receptor protein tyrosine kinase activity	30/5317	60/18639	0.5	1.75277412074478	0.000353001437160966	0.00479391694346417
GO:0005520	insulin-like growth factor binding	13/5317	19/18639	0.684210526315789	2.39853300733496	0.000355880297113061	0.00479391694346417
GO:0004677	DNA-dependent protein kinase activity	95/5317	246/18639	0.386178861788618	1.35376862984353	0.000378035694906721	0.00486656776363328
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	94/5317	243/18639	0.386831275720165	1.35605569835399	0.000378194512013223	0.00486656776363328
GO:0051959	dynein light intermediate chain binding	17/5317	28/18639	0.607142857142857	2.12836857519009	0.000378602234380751	0.00486656776363328
GO:0048185	activin binding	9/5317	11/18639	0.818181818181818	2.86817583394601	0.000378983079118458	0.00486656776363328
GO:0097493	structural molecule activity conferring elasticity	9/5317	11/18639	0.818181818181818	2.86817583394601	0.000378983079118458	0.00486656776363328
GO:0140303	intramembrane lipid transporter activity	24/5317	45/18639	0.533333333333333	1.86962572879443	0.000399982130232697	0.00507573628230271
GO:0035591	signaling adaptor activity	55/5317	129/18639	0.426356589147287	1.49461359133276	0.000408177478494228	0.00507573628230271
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	172/5317	484/18639	0.355371900826446	1.24577334201695	0.000409792374928955	0.00507573628230271
GO:0046332	SMAD binding	37/5317	79/18639	0.468354430379747	1.64183904981157	0.00041004856429083	0.00507573628230271
GO:0140333	glycerophospholipid flippase activity	10/5317	13/18639	0.769230769230769	2.69657557037659	0.000413990708575974	0.00507877887128026
GO:0035402	histone H3T11 kinase activity	95/5317	247/18639	0.384615384615385	1.34828778518829	0.000444305254151679	0.00535504753688077
GO:0035403	histone H3T6 kinase activity	95/5317	247/18639	0.384615384615385	1.34828778518829	0.000444305254151679	0.00535504753688077
GO:0005003	ephrin receptor activity	27/5317	53/18639	0.509433962264151	1.78584533057015	0.000469458926743574	0.00551313303714248
GO:0005005	transmembrane-ephrin receptor activity	27/5317	53/18639	0.509433962264151	1.78584533057015	0.000469458926743574	0.00551313303714248
GO:0038064	collagen receptor activity	27/5317	53/18639	0.509433962264151	1.78584533057015	0.000469458926743574	0.00551313303714248
GO:0019903	protein phosphatase binding	60/5317	144/18639	0.416666666666667	1.46064510062065	0.000475278047558149	0.0055341698080076
GO:0050431	transforming growth factor beta binding	15/5317	24/18639	0.625	2.19096765093098	0.000542069959518258	0.00625885818805115
GO:0030276	clathrin binding	24/5317	46/18639	0.521739130434783	1.82898169121195	0.00061165341425311	0.00700343159319811
GO:0004721	phosphoprotein phosphatase activity	70/5317	175/18639	0.4	1.40221929659582	0.000687303476343948	0.0078045865826164
GO:0001217	DNA-binding transcription repressor activity	104/5317	278/18639	0.37410071942446	1.3114281191184	0.000777773658445065	0.0087595164483895
GO:0023026	MHC class II protein complex binding	16/5317	27/18639	0.592592592592593	2.0773619208827	0.000820908026908579	0.00905139919542245
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	16/5317	27/18639	0.592592592592593	2.0773619208827	0.000820908026908579	0.00905139919542245
GO:0008170	N-methyltransferase activity	43/5317	98/18639	0.438775510204082	1.5381487182046	0.000823453347472931	0.00905139919542245
GO:0043394	proteoglycan binding	20/5317	37/18639	0.540540540540541	1.89489094134571	0.000961339529985481	0.0104461281603516
GO:0005024	transforming growth factor beta receptor activity	11/5317	16/18639	0.6875	2.41006441602407	0.000980750023788467	0.0104461281603516
GO:0140327	flippase activity	11/5317	16/18639	0.6875	2.41006441602407	0.000980750023788467	0.0104461281603516
GO:0140328	floppase activity	11/5317	16/18639	0.6875	2.41006441602407	0.000980750023788467	0.0104461281603516
GO:0140789	histone phosphatase activity	56/5317	136/18639	0.411764705882353	1.44346104061335	0.00100982874199685	0.0106731130115667
GO:0035259	nuclear glucocorticoid receptor binding	9/5317	12/18639	0.75	2.62916118111717	0.00112994712584223	0.0118515064954749
GO:0016279	protein-lysine N-methyltransferase activity	32/5317	69/18639	0.463768115942029	1.62576150329951	0.0012061172185165	0.0124070786880786
GO:1901681	sulfur compound binding	102/5317	275/18639	0.370909090909091	1.30023971138886	0.00120861712163718	0.0124070786880786
GO:0043274	phospholipase binding	14/5317	23/18639	0.608695652173913	2.1338119730806	0.00121000621848802	0.0124070786880786
GO:0005518	collagen binding	33/5317	72/18639	0.458333333333333	1.60670961068272	0.00130817994094564	0.0133143647322912
GO:0051393	alpha-actinin binding	16/5317	28/18639	0.571428571428571	2.00317042370832	0.00141064908361236	0.0142517047123778
GO:0009975	cyclase activity	13/5317	21/18639	0.619047619047619	2.17010129235068	0.00145782744974303	0.0145148906952675
GO:0051010	microtubule plus-end binding	13/5317	21/18639	0.619047619047619	2.17010129235068	0.00145782744974303	0.0145148906952675
GO:0001221	transcription coregulator binding	48/5317	115/18639	0.417391304347826	1.46318535296956	0.00158923930568081	0.0157094590360103
GO:0016278	lysine N-methyltransferase activity	32/5317	70/18639	0.457142857142857	1.60253633896666	0.00162103404119082	0.0159092912328299
GO:0008569	minus-end-directed microtubule motor activity	11/5317	17/18639	0.647058823529412	2.26829592096383	0.00206286870758998	0.019960433832596
GO:0030169	low-density lipoprotein particle binding	11/5317	17/18639	0.647058823529412	2.26829592096383	0.00206286870758998	0.019960433832596
GO:0030020	extracellular matrix structural constituent conferring tensile strength	22/5317	44/18639	0.5	1.75277412074478	0.00209787756906874	0.020157229230073
GO:0019887	protein kinase regulator activity	94/5317	255/18639	0.368627450980392	1.29224131254909	0.00227215340532109	0.0216801304091054
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	98/5317	268/18639	0.365671641791045	1.2818795808432	0.00247788941230783	0.023480138293179
GO:0030021	extracellular matrix structural constituent conferring compression resistance	13/5317	22/18639	0.590909090909091	2.07146032451656	0.00263698683654276	0.0248165747493819
GO:0043560	insulin receptor substrate binding	9/5317	13/18639	0.692307692307692	2.42691801333893	0.0027408490646913	0.0254454501005801
GO:0070123	transforming growth factor beta receptor activity, type III	9/5317	13/18639	0.692307692307692	2.42691801333893	0.0027408490646913	0.0254454501005801
GO:0042805	actinin binding	19/5317	37/18639	0.513513513513513	1.80014639427842	0.00281545005614694	0.0259626065580262
GO:0071813	lipoprotein particle binding	17/5317	32/18639	0.53125	1.86232250329133	0.00292269507529225	0.026594589625507
GO:0071814	protein-lipid complex binding	17/5317	32/18639	0.53125	1.86232250329133	0.00292269507529225	0.026594589625507
GO:0043178	alcohol binding	39/5317	92/18639	0.423913043478261	1.48604762410971	0.00299927382669576	0.027066315722358
GO:0004016	adenylate cyclase activity	8/5317	11/18639	0.727272727272727	2.54948963017423	0.00301393472017524	0.027066315722358
GO:0019209	kinase activator activity	58/5317	148/18639	0.391891891891892	1.37379593247564	0.00324738383819748	0.0289734116472944
GO:0042054	histone methyltransferase activity	30/5317	67/18639	0.447761194029851	1.56964846633861	0.00329432862596745	0.0292026292392211
GO:0140693	molecular condensate scaffold activity	23/5317	48/18639	0.479166666666667	1.67974186571375	0.00338454913025593	0.0298100673395619
GO:0004709	MAP kinase kinase kinase activity	14/5317	25/18639	0.56	1.96310701523415	0.00360413911523865	0.0313423236983412
GO:0042974	nuclear retinoic acid receptor binding	14/5317	25/18639	0.56	1.96310701523415	0.00360413911523865	0.0313423236983412
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	11/5317	18/18639	0.611111111111111	2.14227948091029	0.0039420697347124	0.0338525238468427
GO:0004706	JUN kinase kinase kinase activity	11/5317	18/18639	0.611111111111111	2.14227948091029	0.0039420697347124	0.0338525238468427
GO:0042562	hormone binding	39/5317	94/18639	0.414893617021277	1.45442958955418	0.00469035465325009	0.0400282440594139
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	20/5317	41/18639	0.48780487804878	1.71002353243393	0.00473345326703295	0.040146696227798
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	10/5317	16/18639	0.625	2.19096765093098	0.00477805476251762	0.0402763634582774
GO:0042826	histone deacetylase binding	50/5317	127/18639	0.393700787401575	1.38013710294865	0.00537017657814917	0.0449916013315668
GO:0098632	cell-cell adhesion mediator activity	25/5317	55/18639	0.454545454545455	1.59343101885889	0.00550216144754942	0.0457621701489735
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	37/5317	89/18639	0.415730337078652	1.45736275207993	0.00556206871534103	0.0457621701489735
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	37/5317	89/18639	0.415730337078652	1.45736275207993	0.00556206871534103	0.0457621701489735
GO:0008191	metalloendopeptidase inhibitor activity	9/5317	14/18639	0.642857142857143	2.25356672667186	0.00573560796387197	0.0466201382276749
GO:0005160	transforming growth factor beta receptor binding	14/5317	26/18639	0.538461538461538	1.88760289926361	0.00577779913236761	0.0466201382276749
GO:0070412	R-SMAD binding	14/5317	26/18639	0.538461538461538	1.88760289926361	0.00577779913236761	0.0466201382276749
GO:0008276	protein methyltransferase activity	39/5317	95/18639	0.410526315789474	1.43911980440098	0.0058020696047543	0.0466201382276749
GO:0140938	histone H3 methyltransferase activity	22/5317	47/18639	0.468085106382979	1.64089492154831	0.00584634209629038	0.0467027560482732
GO:0004725	protein tyrosine phosphatase activity	40/5317	98/18639	0.408163265306122	1.43083601693452	0.0059046443241285	0.0468958456725581
GO:0005025	transforming growth factor beta receptor activity, type I	8/5317	12/18639	0.666666666666667	2.33703216099304	0.00678190990884123	0.0517685789708214
GO:0005026	transforming growth factor beta receptor activity, type II	8/5317	12/18639	0.666666666666667	2.33703216099304	0.00678190990884123	0.0517685789708214
GO:0016361	activin receptor activity, type I	8/5317	12/18639	0.666666666666667	2.33703216099304	0.00678190990884123	0.0517685789708214
GO:0016362	activin receptor activity, type II	8/5317	12/18639	0.666666666666667	2.33703216099304	0.00678190990884123	0.0517685789708214
GO:0017002	activin receptor activity	8/5317	12/18639	0.666666666666667	2.33703216099304	0.00678190990884123	0.0517685789708214
GO:0035497	cAMP response element binding	8/5317	12/18639	0.666666666666667	2.33703216099304	0.00678190990884123	0.0517685789708214
GO:1990817	poly(A) RNA polymerase activity	8/5317	12/18639	0.666666666666667	2.33703216099304	0.00678190990884123	0.0517685789708214
GO:0017046	peptide hormone binding	24/5317	53/18639	0.452830188679245	1.58741807161791	0.00683998382379885	0.0519234131154675
GO:0140793	histone H2AXY142 phosphatase activity	37/5317	90/18639	0.411111111111111	1.44116983261238	0.00689254486954493	0.0520349266524986
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	15/5317	29/18639	0.517241379310345	1.81321460766701	0.00704252222041934	0.0528766422451157
GO:0035035	histone acetyltransferase binding	13/5317	24/18639	0.541666666666667	1.89883863080685	0.00726572350970368	0.0542560005561568
GO:0004715	non-membrane spanning protein tyrosine kinase activity	21/5317	45/18639	0.466666666666667	1.63592251269513	0.00730934697936515	0.0542867175656633
GO:0098631	cell adhesion mediator activity	32/5317	76/18639	0.421052631578947	1.47602031220613	0.00762343089789743	0.0563150217941455
GO:0032395	MHC class II receptor activity	7/5317	10/18639	0.7	2.45388376904269	0.00782063506699738	0.0571571945853957
GO:0043121	neurotrophin binding	7/5317	10/18639	0.7	2.45388376904269	0.00782063506699738	0.0571571945853957
GO:0030331	nuclear estrogen receptor binding	19/5317	40/18639	0.475	1.66513541470754	0.00833654663220262	0.0606053707547429
GO:0046965	nuclear retinoid X receptor binding	10/5317	17/18639	0.588235294117647	2.06208720087621	0.00865689198384281	0.0626029978200001
GO:0032934	sterol binding	29/5317	68/18639	0.426470588235294	1.49501322063525	0.00875423491699606	0.0626474936247531
GO:1990841	promoter-specific chromatin binding	29/5317	68/18639	0.426470588235294	1.49501322063525	0.00875423491699606	0.0626474936247531
GO:0030295	protein kinase activator activity	53/5317	139/18639	0.381294964028777	1.3366478906399	0.0089194270990916	0.0634989266018231
GO:0001540	amyloid-beta binding	34/5317	83/18639	0.409638554216867	1.43600771338127	0.00993278808258524	0.0703487155952171
GO:0001965	G-protein alpha-subunit binding	15/5317	30/18639	0.5	1.75277412074478	0.0104202642041756	0.0730481786558023
GO:0001968	fibronectin binding	15/5317	30/18639	0.5	1.75277412074478	0.0104202642041756	0.0730481786558023
GO:0019888	protein phosphatase regulator activity	42/5317	107/18639	0.392523364485981	1.3760095901174	0.0107031496256817	0.0737282282846346
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	9/5317	15/18639	0.6	2.10332894489374	0.0107319109584621	0.0737282282846346
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	9/5317	15/18639	0.6	2.10332894489374	0.0107319109584621	0.0737282282846346
GO:0051371	muscle alpha-actinin binding	9/5317	15/18639	0.6	2.10332894489374	0.0107319109584621	0.0737282282846346
GO:0003707	nuclear steroid receptor activity	13/5317	25/18639	0.52	1.82288508557457	0.0112324399370408	0.0767829476293237
GO:0052745	inositol phosphate phosphatase activity	11/5317	20/18639	0.55	1.92805153281926	0.0115293346909388	0.0784223062641083
GO:0019208	phosphatase regulator activity	45/5317	117/18639	0.384615384615385	1.34828778518829	0.0127283353170717	0.0861513927372241
GO:0044390	ubiquitin-like protein conjugating enzyme binding	17/5317	36/18639	0.472222222222222	1.6553977807034	0.0131546836884156	0.0882959749124549
GO:0045499	chemorepellent activity	14/5317	28/18639	0.5	1.75277412074478	0.0131737080473459	0.0882959749124549
GO:0046975	histone H3K36 methyltransferase activity	8/5317	13/18639	0.615384615384615	2.15726045630127	0.0132476072594811	0.0883602542452769
GO:0097110	scaffold protein binding	29/5317	70/18639	0.414285714285714	1.45229855718853	0.0138338289667517	0.0918245458952506
GO:0031625	ubiquitin protein ligase binding	104/5317	302/18639	0.344370860927152	1.20720866594343	0.0139749720764229	0.0923154405432934
GO:0003887	DNA-directed DNA polymerase activity	12/5317	23/18639	0.521739130434783	1.82898169121195	0.014225235884339	0.0935190148568506
GO:0044325	transmembrane transporter binding	51/5317	136/18639	0.375	1.31458059055859	0.014403927624198	0.0942428407411815
GO:0140272	exogenous protein binding	33/5317	82/18639	0.402439024390244	1.41076941425799	0.0147283480879364	0.0959087690655197
GO:0000149	SNARE binding	41/5317	106/18639	0.386792452830189	1.3559196028403	0.0151950122087559	0.0984808810133522
GO:0001786	phosphatidylserine binding	25/5317	59/18639	0.423728813559322	1.48540179724134	0.0156527297971664	0.10049930252947
GO:0070063	RNA polymerase binding	25/5317	59/18639	0.423728813559322	1.48540179724134	0.0156527297971664	0.10049930252947
GO:0002162	dystroglycan binding	7/5317	11/18639	0.636363636363636	2.23080342640245	0.0162323606739361	0.101378470754492
GO:0003953	NAD+ nucleosidase activity	7/5317	11/18639	0.636363636363636	2.23080342640245	0.0162323606739361	0.101378470754492
GO:0034056	estrogen response element binding	7/5317	11/18639	0.636363636363636	2.23080342640245	0.0162323606739361	0.101378470754492
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	7/5317	11/18639	0.636363636363636	2.23080342640245	0.0162323606739361	0.101378470754492
GO:0042608	T cell receptor binding	7/5317	11/18639	0.636363636363636	2.23080342640245	0.0162323606739361	0.101378470754492
GO:0180030	inositol phosphate kinase activity	7/5317	11/18639	0.636363636363636	2.23080342640245	0.0162323606739361	0.101378470754492
GO:0052866	phosphatidylinositol phosphate phosphatase activity	16/5317	34/18639	0.470588235294118	1.64966976070097	0.016552337611418	0.102816362955673
GO:0004435	phosphatidylinositol phospholipase C activity	13/5317	26/18639	0.5	1.75277412074478	0.016687080741714	0.102816362955673
GO:0008143	poly(A) binding	13/5317	26/18639	0.5	1.75277412074478	0.016687080741714	0.102816362955673
GO:0016887	ATP hydrolysis activity	139/5317	417/18639	0.333333333333333	1.16851608049652	0.0170253797406353	0.104432463230504
GO:0032266	phosphatidylinositol-3-phosphate binding	21/5317	48/18639	0.4375	1.53367735565168	0.0172265803214128	0.105196983829428
GO:0008237	metallopeptidase activity	66/5317	184/18639	0.358695652173913	1.25742491270821	0.0178807426055362	0.108335290441071
GO:0023023	MHC protein complex binding	17/5317	37/18639	0.459459459459459	1.61065730014385	0.0179862435470189	0.108335290441071
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	34/5317	86/18639	0.395348837209302	1.38591442105401	0.0179926890027475	0.108335290441071
GO:0009931	calcium-dependent protein serine/threonine kinase activity	11/5317	21/18639	0.523809523809524	1.83623955506596	0.0180558817401785	0.108335290441071
GO:0070411	I-SMAD binding	9/5317	16/18639	0.5625	1.97187088583788	0.0183868689246764	0.10984155609785
GO:0015485	cholesterol binding	23/5317	54/18639	0.425925925925926	1.49310388063444	0.018640546559136	0.110874939273822
GO:0004629	phospholipase C activity	14/5317	29/18639	0.482758620689655	1.69233363382255	0.0188961481524773	0.111910808454758
GO:0001098	basal transcription machinery binding	25/5317	60/18639	0.416666666666667	1.46064510062065	0.0197139388083656	0.115756204797839
GO:0001099	basal RNA polymerase II transcription machinery binding	25/5317	60/18639	0.416666666666667	1.46064510062065	0.0197139388083656	0.115756204797839
GO:0044389	ubiquitin-like protein ligase binding	109/5317	322/18639	0.338509316770186	1.18666074013156	0.0203314676084743	0.118874197846995
GO:0008235	metalloexopeptidase activity	27/5317	66/18639	0.409090909090909	1.434087916973	0.0205003067074925	0.119353480576673
GO:1902936	phosphatidylinositol bisphosphate binding	42/5317	111/18639	0.378378378378378	1.326423658942	0.0210340405021793	0.12161857005362
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	12/5317	24/18639	0.5	1.75277412074478	0.0211847482589743	0.12161857005362
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	12/5317	24/18639	0.5	1.75277412074478	0.0211847482589743	0.12161857005362
GO:0003725	double-stranded RNA binding	30/5317	75/18639	0.4	1.40221929659582	0.0212434183499773	0.12161857005362
GO:0001618	virus receptor activity	32/5317	81/18639	0.395061728395062	1.38490794725514	0.0215047973844659	0.122604114548781
GO:0019210	kinase inhibitor activity	35/5317	90/18639	0.388888888888889	1.36326876057927	0.0216247359433953	0.122778459447211
GO:0001222	transcription corepressor binding	21/5317	49/18639	0.428571428571429	1.50237781778124	0.0222131078015874	0.125600041643543
GO:0005161	platelet-derived growth factor receptor binding	8/5317	14/18639	0.571428571428571	2.00317042370832	0.0232636063202934	0.12837026138186
GO:0005344	oxygen carrier activity	8/5317	14/18639	0.571428571428571	2.00317042370832	0.0232636063202934	0.12837026138186
GO:0032454	histone H3K9 demethylase activity	8/5317	14/18639	0.571428571428571	2.00317042370832	0.0232636063202934	0.12837026138186
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	8/5317	14/18639	0.571428571428571	2.00317042370832	0.0232636063202934	0.12837026138186
GO:0046030	inositol trisphosphate phosphatase activity	8/5317	14/18639	0.571428571428571	2.00317042370832	0.0232636063202934	0.12837026138186
GO:0098821	BMP receptor activity	8/5317	14/18639	0.571428571428571	2.00317042370832	0.0232636063202934	0.12837026138186
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	13/5317	27/18639	0.481481481481481	1.6878565607172	0.0239304481892134	0.131521743247917
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	17/5317	38/18639	0.447368421052632	1.56827158171901	0.0240735770693953	0.131781254555176
GO:0031624	ubiquitin conjugating enzyme binding	14/5317	30/18639	0.466666666666667	1.63592251269513	0.0263125466072414	0.142898968531026
GO:0070566	adenylyltransferase activity	14/5317	30/18639	0.466666666666667	1.63592251269513	0.0263125466072414	0.142898968531026
GO:0070034	telomerase RNA binding	11/5317	22/18639	0.5	1.75277412074478	0.0269647054626223	0.145541836783735
GO:0005319	lipid transporter activity	63/5317	178/18639	0.353932584269663	1.24072774839237	0.0270110395777674	0.145541836783735
GO:0030296	protein tyrosine kinase activator activity	15/5317	33/18639	0.454545454545455	1.59343101885889	0.0283613439058509	0.151628352243732
GO:0140416	transcription regulator inhibitor activity	15/5317	33/18639	0.454545454545455	1.59343101885889	0.0283613439058509	0.151628352243732
GO:0005525	GTP binding	125/5317	378/18639	0.330687830687831	1.15924214334972	0.0287638542882685	0.153184247256128
GO:0015278	intracellularly gated calcium channel activity	9/5317	17/18639	0.529411764705882	1.85587848078859	0.0293330929831142	0.155104025508524
GO:0017166	vinculin binding	7/5317	12/18639	0.583333333333333	2.04490314086891	0.0294629917450689	0.155104025508524
GO:1990247	N6-methyladenosine-containing RNA reader activity	7/5317	12/18639	0.583333333333333	2.04490314086891	0.0294629917450689	0.155104025508524
GO:0042277	peptide binding	85/5317	249/18639	0.34136546184739	1.19667309448439	0.0300370917978921	0.156710214876061
GO:0000993	RNA polymerase II complex binding	16/5317	36/18639	0.444444444444444	1.55802144066203	0.0301102596268415	0.156710214876061
GO:0045505	dynein intermediate chain binding	16/5317	36/18639	0.444444444444444	1.55802144066203	0.0301102596268415	0.156710214876061
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	59/5317	167/18639	0.353293413173653	1.23848710328074	0.0326278742818801	0.168354466383515
GO:1990782	protein tyrosine kinase binding	43/5317	117/18639	0.367521367521368	1.28836388362437	0.0326489782640903	0.168354466383515
GO:0035198	miRNA binding	18/5317	42/18639	0.428571428571429	1.50237781778124	0.0328376979554454	0.168354466383515
GO:0043175	RNA polymerase core enzyme binding	18/5317	42/18639	0.428571428571429	1.50237781778124	0.0328376979554454	0.168354466383515
GO:0004857	enzyme inhibitor activity	136/5317	416/18639	0.326923076923077	1.14604461741005	0.0334989855965635	0.171106342786908
GO:0008009	chemokine activity	19/5317	45/18639	0.422222222222222	1.48012036862893	0.0338746723058189	0.171400431847031
GO:0004843	cysteine-type deubiquitinase activity	40/5317	108/18639	0.37037037037037	1.29835120055169	0.0338896839769669	0.171400431847031
GO:0016741	transferase activity, transferring one-carbon groups	74/5317	215/18639	0.344186046511628	1.20656079009408	0.0339307987353656	0.171400431847031
GO:0002020	protease binding	49/5317	136/18639	0.360294117647059	1.26302841053668	0.0342446345858523	0.171648778938083
GO:0016004	phospholipase activator activity	10/5317	20/18639	0.5	1.75277412074478	0.0344269754502742	0.171648778938083
GO:0019001	guanyl nucleotide binding	131/5317	400/18639	0.3275	1.14806704908783	0.0344796673849424	0.171648778938083
GO:0032561	guanyl ribonucleotide binding	131/5317	400/18639	0.3275	1.14806704908783	0.0344796673849424	0.171648778938083
GO:0017147	Wnt-protein binding	14/5317	31/18639	0.451612903225806	1.58315081873722	0.0356706937883104	0.176300479371002
GO:0070273	phosphatidylinositol-4-phosphate binding	14/5317	31/18639	0.451612903225806	1.58315081873722	0.0356706937883104	0.176300479371002
GO:0019783	ubiquitin-like protein peptidase activity	46/5317	127/18639	0.362204724409449	1.26972613471275	0.035893292800477	0.176764818307725
GO:0008081	phosphoric diester hydrolase activity	33/5317	87/18639	0.379310344827586	1.32969071228914	0.0362778431649105	0.176847160209451
GO:0016504	peptidase activator activity	23/5317	57/18639	0.403508771929825	1.41451946586421	0.036392117394149	0.176847160209451
GO:0004860	protein kinase inhibitor activity	32/5317	84/18639	0.380952380952381	1.33544694913888	0.0365219937860769	0.176847160209451
GO:0051117	ATPase binding	32/5317	84/18639	0.380952380952381	1.33544694913888	0.0365219937860769	0.176847160209451
GO:0002039	p53 binding	27/5317	69/18639	0.391304347826087	1.37173626840896	0.0371057493174626	0.176847160209451
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	6/5317	10/18639	0.6	2.10332894489374	0.0373258198404227	0.176847160209451
GO:0004445	inositol-polyphosphate 5-phosphatase activity	6/5317	10/18639	0.6	2.10332894489374	0.0373258198404227	0.176847160209451
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	6/5317	10/18639	0.6	2.10332894489374	0.0373258198404227	0.176847160209451
GO:0031434	mitogen-activated protein kinase kinase binding	6/5317	10/18639	0.6	2.10332894489374	0.0373258198404227	0.176847160209451
GO:0031720	haptoglobin binding	6/5317	10/18639	0.6	2.10332894489374	0.0373258198404227	0.176847160209451
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	6/5317	10/18639	0.6	2.10332894489374	0.0373258198404227	0.176847160209451
GO:0004953	icosanoid receptor activity	8/5317	15/18639	0.533333333333333	1.86962572879443	0.0375855438766719	0.176858004405983
GO:0005041	low-density lipoprotein particle receptor activity	8/5317	15/18639	0.533333333333333	1.86962572879443	0.0375855438766719	0.176858004405983
GO:0001664	G protein-coupled receptor binding	99/5317	297/18639	0.333333333333333	1.16851608049652	0.0386108164185741	0.18059478652888
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	11/5317	23/18639	0.478260869565217	1.67656655027762	0.0386425525760485	0.18059478652888
GO:0061134	peptidase regulator activity	77/5317	226/18639	0.34070796460177	1.19436820617122	0.0389406336151775	0.181370951143234
GO:0003774	cytoskeletal motor activity	54/5317	153/18639	0.352941176470588	1.23725232052573	0.0402100372557788	0.186650645910271
GO:0004532	RNA exonuclease activity	17/5317	40/18639	0.425	1.48985800263306	0.0407083107308089	0.187713271552223
GO:0008168	methyltransferase activity	70/5317	204/18639	0.343137254901961	1.20288420051112	0.040712194266785	0.187713271552223
GO:0005126	cytokine receptor binding	92/5317	275/18639	0.334545454545455	1.17276522988014	0.0410457727283094	0.188618366985609
GO:0048156	tau protein binding	18/5317	43/18639	0.418604651162791	1.46743879876307	0.0418075835417235	0.189041708393626
GO:0000287	magnesium ion binding	78/5317	230/18639	0.339130434782609	1.18883809928776	0.0419668933385089	0.189041708393626
GO:0004112	cyclic-nucleotide phosphodiesterase activity	12/5317	26/18639	0.461538461538462	1.61794534222595	0.0421009918256547	0.189041708393626
GO:0030247	polysaccharide binding	12/5317	26/18639	0.461538461538462	1.61794534222595	0.0421009918256547	0.189041708393626
GO:0034237	protein kinase A regulatory subunit binding	12/5317	26/18639	0.461538461538462	1.61794534222595	0.0421009918256547	0.189041708393626
GO:0052742	phosphatidylinositol kinase activity	12/5317	26/18639	0.461538461538462	1.61794534222595	0.0421009918256547	0.189041708393626
GO:0070006	metalloaminopeptidase activity	12/5317	26/18639	0.461538461538462	1.61794534222595	0.0421009918256547	0.189041708393626
GO:0000400	four-way junction DNA binding	9/5317	18/18639	0.5	1.75277412074478	0.0441157661709727	0.195532460383602
GO:0008525	phosphatidylcholine transporter activity	9/5317	18/18639	0.5	1.75277412074478	0.0441157661709727	0.195532460383602
GO:0015172	acidic amino acid transmembrane transporter activity	9/5317	18/18639	0.5	1.75277412074478	0.0441157661709727	0.195532460383602
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	9/5317	18/18639	0.5	1.75277412074478	0.0441157661709727	0.195532460383602
GO:0061980	regulatory RNA binding	23/5317	58/18639	0.396551724137931	1.39013119921138	0.0444634152738805	0.196439654618366
GO:0043236	laminin binding	13/5317	29/18639	0.448275862068966	1.57145265997808	0.0449178629419117	0.197811357955726
GO:0070717	poly-purine tract binding	14/5317	32/18639	0.4375	1.53367735565168	0.0471944547619891	0.207173101734738
GO:0000175	3'-5'-RNA exonuclease activity	15/5317	35/18639	0.428571428571429	1.50237781778124	0.0490165902469797	0.213805698410635
GO:0005154	epidermal growth factor receptor binding	15/5317	35/18639	0.428571428571429	1.50237781778124	0.0490165902469797	0.213805698410635
GO:0003727	single-stranded RNA binding	33/5317	89/18639	0.370786516853933	1.29981002212534	0.0496394205019184	0.215837227119101
GO:0004386	helicase activity	54/5317	155/18639	0.348387096774194	1.22128777445443	0.0505810721635521	0.219237833289339
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	31/5317	83/18639	0.373493975903614	1.30930115043586	0.0508139687524392	0.219554695175634
GO:0001223	transcription coactivator binding	18/5317	44/18639	0.409090909090909	1.434087916973	0.0524151593056423	0.225763099955964
GO:0005548	phospholipid transporter activity	26/5317	68/18639	0.382352941176471	1.34035668056954	0.0531194351492042	0.227218511207821
GO:0030215	semaphorin receptor binding	11/5317	24/18639	0.458333333333333	1.60670961068272	0.0534145408443421	0.227218511207821
GO:0050699	WW domain binding	11/5317	24/18639	0.458333333333333	1.60670961068272	0.0534145408443421	0.227218511207821
GO:0060229	lipase activator activity	11/5317	24/18639	0.458333333333333	1.60670961068272	0.0534145408443421	0.227218511207821
GO:0140296	general transcription initiation factor binding	21/5317	53/18639	0.39622641509434	1.38899081266568	0.0536838790955245	0.227659413201391
GO:0004683	calcium/calmodulin-dependent protein kinase activity	12/5317	27/18639	0.444444444444444	1.55802144066203	0.0566374267348079	0.236428838395724
GO:0008266	poly(U) RNA binding	12/5317	27/18639	0.444444444444444	1.55802144066203	0.0566374267348079	0.236428838395724
GO:0005159	insulin-like growth factor receptor binding	8/5317	16/18639	0.5	1.75277412074478	0.0567842188286673	0.236428838395724
GO:0005324	long-chain fatty acid transmembrane transporter activity	8/5317	16/18639	0.5	1.75277412074478	0.0567842188286673	0.236428838395724
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	8/5317	16/18639	0.5	1.75277412074478	0.0567842188286673	0.236428838395724
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	8/5317	16/18639	0.5	1.75277412074478	0.0567842188286673	0.236428838395724
GO:0101005	deubiquitinase activity	41/5317	115/18639	0.356521739130435	1.2498041556615	0.0576627738955479	0.239361484388166
GO:0008187	poly-pyrimidine tract binding	13/5317	30/18639	0.433333333333333	1.51907090464548	0.0591454577860711	0.241613593609132
GO:0017018	myosin phosphatase activity	31/5317	84/18639	0.369047619047619	1.29371423197829	0.0591734258082361	0.241613593609132
GO:0033192	calmodulin-dependent protein phosphatase activity	30/5317	81/18639	0.37037037037037	1.29835120055169	0.0599637812377832	0.241613593609132
GO:0140791	histone H2AXS140 phosphatase activity	30/5317	81/18639	0.37037037037037	1.29835120055169	0.0599637812377832	0.241613593609132
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	30/5317	81/18639	0.37037037037037	1.29835120055169	0.0599637812377832	0.241613593609132
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	30/5317	81/18639	0.37037037037037	1.29835120055169	0.0599637812377832	0.241613593609132
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	30/5317	81/18639	0.37037037037037	1.29835120055169	0.0599637812377832	0.241613593609132
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	30/5317	81/18639	0.37037037037037	1.29835120055169	0.0599637812377832	0.241613593609132
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	30/5317	81/18639	0.37037037037037	1.29835120055169	0.0599637812377832	0.241613593609132
GO:1990439	MAP kinase serine/threonine phosphatase activity	30/5317	81/18639	0.37037037037037	1.29835120055169	0.0599637812377832	0.241613593609132
GO:0099106	ion channel regulator activity	55/5317	160/18639	0.34375	1.20503220801204	0.0615238892072794	0.245198210639441
GO:0000099	sulfur amino acid transmembrane transporter activity	6/5317	11/18639	0.545454545454545	1.91211722263067	0.0626379708402065	0.245198210639441
GO:0004954	prostanoid receptor activity	6/5317	11/18639	0.545454545454545	1.91211722263067	0.0626379708402065	0.245198210639441
GO:0010854	adenylate cyclase regulator activity	6/5317	11/18639	0.545454545454545	1.91211722263067	0.0626379708402065	0.245198210639441
GO:0019215	intermediate filament binding	6/5317	11/18639	0.545454545454545	1.91211722263067	0.0626379708402065	0.245198210639441
GO:0034713	type I transforming growth factor beta receptor binding	6/5317	11/18639	0.545454545454545	1.91211722263067	0.0626379708402065	0.245198210639441
GO:0050786	RAGE receptor binding	6/5317	11/18639	0.545454545454545	1.91211722263067	0.0626379708402065	0.245198210639441
GO:0050998	nitric-oxide synthase binding	6/5317	11/18639	0.545454545454545	1.91211722263067	0.0626379708402065	0.245198210639441
GO:0140031	phosphorylation-dependent protein binding	6/5317	11/18639	0.545454545454545	1.91211722263067	0.0626379708402065	0.245198210639441
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	6/5317	11/18639	0.545454545454545	1.91211722263067	0.0626379708402065	0.245198210639441
GO:0043395	heparan sulfate proteoglycan binding	9/5317	19/18639	0.473684210526316	1.6605228512319	0.0631396161613023	0.245761565455041
GO:1990380	K48-linked deubiquitinase activity	9/5317	19/18639	0.473684210526316	1.6605228512319	0.0631396161613023	0.245761565455041
GO:0008307	structural constituent of muscle	17/5317	42/18639	0.404761904761905	1.41891238346006	0.0643118417758248	0.249617148587523
GO:0003925	G protein activity	21/5317	54/18639	0.388888888888889	1.36326876057927	0.0649573374223231	0.251412342586681
GO:0008093	cytoskeletal anchor activity	10/5317	22/18639	0.454545454545455	1.59343101885889	0.0679306899568107	0.259990997216317
GO:0031683	G-protein beta/gamma-subunit complex binding	10/5317	22/18639	0.454545454545455	1.59343101885889	0.0679306899568107	0.259990997216317
GO:0046972	histone H4K16 acetyltransferase activity	10/5317	22/18639	0.454545454545455	1.59343101885889	0.0679306899568107	0.259990997216317
GO:0050321	tau-protein kinase activity	10/5317	22/18639	0.454545454545455	1.59343101885889	0.0679306899568107	0.259990997216317
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	30/5317	82/18639	0.365853658536585	1.28251764932545	0.0695488481491648	0.264709466362749
GO:0033549	MAP kinase phosphatase activity	30/5317	82/18639	0.365853658536585	1.28251764932545	0.0695488481491648	0.264709466362749
GO:0017022	myosin binding	28/5317	76/18639	0.368421052631579	1.29151777318036	0.0716549043330071	0.271971929705944
GO:0004705	JUN kinase activity	7/5317	14/18639	0.5	1.75277412074478	0.0734982743028828	0.274420187206959
GO:0005545	1-phosphatidylinositol binding	7/5317	14/18639	0.5	1.75277412074478	0.0734982743028828	0.274420187206959
GO:0019992	diacylglycerol binding	7/5317	14/18639	0.5	1.75277412074478	0.0734982743028828	0.274420187206959
GO:0042043	neurexin family protein binding	7/5317	14/18639	0.5	1.75277412074478	0.0734982743028828	0.274420187206959
GO:0071933	Arp2/3 complex binding	7/5317	14/18639	0.5	1.75277412074478	0.0734982743028828	0.274420187206959
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	7/5317	14/18639	0.5	1.75277412074478	0.0734982743028828	0.274420187206959
GO:0051019	mitogen-activated protein kinase binding	12/5317	28/18639	0.428571428571429	1.50237781778124	0.07417577955179	0.275452759740971
GO:0141052	histone H3 demethylase activity	12/5317	28/18639	0.428571428571429	1.50237781778124	0.07417577955179	0.275452759740971
GO:0016878	acid-thiol ligase activity	13/5317	31/18639	0.419354838709677	1.47006861739885	0.0760994540066759	0.281077015605303
GO:0070325	lipoprotein particle receptor binding	13/5317	31/18639	0.419354838709677	1.47006861739885	0.0760994540066759	0.281077015605303
GO:0008408	3'-5' exonuclease activity	22/5317	58/18639	0.379310344827586	1.32969071228914	0.0770943743853257	0.283749510363886
GO:0030332	cyclin binding	14/5317	34/18639	0.411764705882353	1.44346104061335	0.0774425519552089	0.283749510363886
GO:0090482	vitamin transmembrane transporter activity	14/5317	34/18639	0.411764705882353	1.44346104061335	0.0774425519552089	0.283749510363886
GO:0005496	steroid binding	38/5317	108/18639	0.351851851851852	1.23343364052411	0.0782955249056864	0.284991994693287
GO:0030159	signaling receptor complex adaptor activity	20/5317	52/18639	0.384615384615385	1.34828778518829	0.0783131294837538	0.284991994693287
GO:0042393	histone binding	81/5317	247/18639	0.327935222672065	1.14959274316054	0.0785182303917558	0.284991994693287
GO:0004180	carboxypeptidase activity	18/5317	46/18639	0.391304347826087	1.37173626840896	0.0789791311546146	0.284991994693287
GO:0004712	protein serine/threonine/tyrosine kinase activity	17/5317	43/18639	0.395348837209302	1.38591442105401	0.0790261644673525	0.284991994693287
GO:0008375	acetylglucosaminyltransferase activity	17/5317	43/18639	0.395348837209302	1.38591442105401	0.0790261644673525	0.284991994693287
GO:0003697	single-stranded DNA binding	42/5317	121/18639	0.347107438016529	1.21680186894679	0.0810064745971805	0.29124932559606
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	8/5317	17/18639	0.470588235294118	1.64966976070097	0.0811852195802701	0.29124932559606
GO:0008238	exopeptidase activity	36/5317	102/18639	0.352941176470588	1.23725232052573	0.0815183422424545	0.291682818336283
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	9/5317	20/18639	0.45	1.5774967086703	0.0866317767430525	0.307576385645876
GO:0030742	GTP-dependent protein binding	9/5317	20/18639	0.45	1.5774967086703	0.0866317767430525	0.307576385645876
GO:0140939	histone H4 methyltransferase activity	9/5317	20/18639	0.45	1.5774967086703	0.0866317767430525	0.307576385645876
GO:0003777	microtubule motor activity	25/5317	68/18639	0.367647058823529	1.28880450054763	0.0870985178765903	0.308436504026894
GO:0044013	histone H2B acetyltransferase activity	10/5317	23/18639	0.434782608695652	1.52415140934329	0.0904600264035507	0.319516905600202
GO:0015459	potassium channel regulator activity	22/5317	59/18639	0.372881355932203	1.30715358157238	0.0909675524509789	0.320485684788833
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	12/5317	29/18639	0.413793103448276	1.45057168613361	0.0948284265705278	0.325756879096221
GO:0097472	cyclin-dependent protein kinase activity	12/5317	29/18639	0.413793103448276	1.45057168613361	0.0948284265705278	0.325756879096221
GO:0099604	ligand-gated calcium channel activity	12/5317	29/18639	0.413793103448276	1.45057168613361	0.0948284265705278	0.325756879096221
GO:0016248	channel inhibitor activity	17/5317	44/18639	0.386363636363636	1.35441636603006	0.0957812417913924	0.325756879096221
GO:0005078	MAP-kinase scaffold activity	6/5317	12/18639	0.5	1.75277412074478	0.0958129499353442	0.325756879096221
GO:0016208	AMP binding	6/5317	12/18639	0.5	1.75277412074478	0.0958129499353442	0.325756879096221
GO:0035014	phosphatidylinositol 3-kinase regulator activity	6/5317	12/18639	0.5	1.75277412074478	0.0958129499353442	0.325756879096221
GO:0045295	gamma-catenin binding	6/5317	12/18639	0.5	1.75277412074478	0.0958129499353442	0.325756879096221
GO:0070679	inositol 1,4,5 trisphosphate binding	6/5317	12/18639	0.5	1.75277412074478	0.0958129499353442	0.325756879096221
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	6/5317	12/18639	0.5	1.75277412074478	0.0958129499353442	0.325756879096221
GO:0141221	histone deacetylase activity, hydrolytic mechanism	6/5317	12/18639	0.5	1.75277412074478	0.0958129499353442	0.325756879096221
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	6/5317	12/18639	0.5	1.75277412074478	0.0958129499353442	0.325756879096221
GO:0120015	sterol transfer activity	13/5317	32/18639	0.40625	1.42412897310513	0.0958765587530408	0.325756879096221
GO:0001727	lipid kinase activity	16/5317	41/18639	0.390243902439024	1.36801882594715	0.0962676216217338	0.325756879096221
GO:0017080	sodium channel regulator activity	16/5317	41/18639	0.390243902439024	1.36801882594715	0.0962676216217338	0.325756879096221
GO:0140566	histone reader activity	14/5317	35/18639	0.4	1.40221929659582	0.096393193094028	0.325756879096221
GO:0000146	microfilament motor activity	15/5317	38/18639	0.394736842105263	1.38376904269325	0.0964942138225342	0.325756879096221
GO:0016247	channel regulator activity	56/5317	168/18639	0.333333333333333	1.16851608049652	0.098008598581547	0.330058368752563
GO:0004222	metalloendopeptidase activity	38/5317	110/18639	0.345454545454545	1.21100757433276	0.0989352496212088	0.332364383813058
GO:0072341	modified amino acid binding	32/5317	91/18639	0.351648351648352	1.23272026074358	0.10020859119097	0.335820986088764
GO:0042809	nuclear vitamin D receptor binding	7/5317	15/18639	0.466666666666667	1.63592251269513	0.104921913425818	0.348219103978438
GO:0050700	CARD domain binding	7/5317	15/18639	0.466666666666667	1.63592251269513	0.104921913425818	0.348219103978438
GO:0120283	protein serine/threonine kinase binding	7/5317	15/18639	0.466666666666667	1.63592251269513	0.104921913425818	0.348219103978438
GO:0140776	protein-containing complex destabilizing activity	7/5317	15/18639	0.466666666666667	1.63592251269513	0.104921913425818	0.348219103978438
GO:0017075	syntaxin-1 binding	8/5317	18/18639	0.444444444444444	1.55802144066203	0.110840782307708	0.362607702120931
GO:0017128	phospholipid scramblase activity	8/5317	18/18639	0.444444444444444	1.55802144066203	0.110840782307708	0.362607702120931
GO:0030228	lipoprotein particle receptor activity	8/5317	18/18639	0.444444444444444	1.55802144066203	0.110840782307708	0.362607702120931
GO:0034185	apolipoprotein binding	8/5317	18/18639	0.444444444444444	1.55802144066203	0.110840782307708	0.362607702120931
GO:0035615	clathrin adaptor activity	8/5317	18/18639	0.444444444444444	1.55802144066203	0.110840782307708	0.362607702120931
GO:0070064	proline-rich region binding	8/5317	18/18639	0.444444444444444	1.55802144066203	0.110840782307708	0.362607702120931
GO:0141110	transporter inhibitor activity	17/5317	45/18639	0.377777777777778	1.32431822456272	0.114606166181622	0.371252522811999
GO:0005248	voltage-gated sodium channel activity	9/5317	21/18639	0.428571428571429	1.50237781778124	0.114623268364844	0.371252522811999
GO:0036122	BMP binding	9/5317	21/18639	0.428571428571429	1.50237781778124	0.114623268364844	0.371252522811999
GO:0140312	cargo adaptor activity	9/5317	21/18639	0.428571428571429	1.50237781778124	0.114623268364844	0.371252522811999
GO:0019894	kinesin binding	16/5317	42/18639	0.380952380952381	1.33544694913888	0.115932716911524	0.371252522811999
GO:0141108	transporter regulator activity	56/5317	170/18639	0.329411764705882	1.15476883249068	0.116847875699175	0.371252522811999
GO:0001091	RNA polymerase II general transcription initiation factor binding	10/5317	24/18639	0.416666666666667	1.46064510062065	0.116921087517271	0.371252522811999
GO:0015149	hexose transmembrane transporter activity	10/5317	24/18639	0.416666666666667	1.46064510062065	0.116921087517271	0.371252522811999
GO:0043998	histone H2A acetyltransferase activity	10/5317	24/18639	0.416666666666667	1.46064510062065	0.116921087517271	0.371252522811999
GO:0055056	D-glucose transmembrane transporter activity	10/5317	24/18639	0.416666666666667	1.46064510062065	0.116921087517271	0.371252522811999
GO:0070300	phosphatidic acid binding	10/5317	24/18639	0.416666666666667	1.46064510062065	0.116921087517271	0.371252522811999
GO:0000217	DNA secondary structure binding	15/5317	39/18639	0.384615384615385	1.34828778518829	0.117066439365799	0.371252522811999
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	15/5317	39/18639	0.384615384615385	1.34828778518829	0.117066439365799	0.371252522811999
GO:0005484	SNAP receptor activity	14/5317	36/18639	0.388888888888889	1.36326876057927	0.117948153714814	0.371252522811999
GO:0016405	CoA-ligase activity	11/5317	27/18639	0.407407407407407	1.42818632060686	0.118157182224757	0.371252522811999
GO:0032452	histone demethylase activity	12/5317	30/18639	0.4	1.40221929659582	0.118617072426832	0.371252522811999
GO:0043995	histone H4K5 acetyltransferase activity	12/5317	30/18639	0.4	1.40221929659582	0.118617072426832	0.371252522811999
GO:0043996	histone H4K8 acetyltransferase activity	12/5317	30/18639	0.4	1.40221929659582	0.118617072426832	0.371252522811999
GO:0043997	histone H4K12 acetyltransferase activity	12/5317	30/18639	0.4	1.40221929659582	0.118617072426832	0.371252522811999
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	43/5317	128/18639	0.3359375	1.1776451123754	0.120722782078145	0.376984324034934
GO:0008094	ATP-dependent activity, acting on DNA	68/5317	210/18639	0.323809523809524	1.13512990676805	0.122238577318132	0.37828396986105
GO:0061135	endopeptidase regulator activity	60/5317	184/18639	0.326086956521739	1.14311355700747	0.125638966905884	0.37828396986105
GO:0004382	GDP phosphatase activity	5/5317	10/18639	0.5	1.75277412074478	0.12609465662035	0.37828396986105
GO:0004955	prostaglandin receptor activity	5/5317	10/18639	0.5	1.75277412074478	0.12609465662035	0.37828396986105
GO:0005031	tumor necrosis factor receptor activity	5/5317	10/18639	0.5	1.75277412074478	0.12609465662035	0.37828396986105
GO:0005131	growth hormone receptor binding	5/5317	10/18639	0.5	1.75277412074478	0.12609465662035	0.37828396986105
GO:0005522	profilin binding	5/5317	10/18639	0.5	1.75277412074478	0.12609465662035	0.37828396986105
GO:0008190	eukaryotic initiation factor 4E binding	5/5317	10/18639	0.5	1.75277412074478	0.12609465662035	0.37828396986105
GO:0016175	superoxide-generating NAD(P)H oxidase activity	5/5317	10/18639	0.5	1.75277412074478	0.12609465662035	0.37828396986105
GO:0016303	1-phosphatidylinositol-3-kinase activity	5/5317	10/18639	0.5	1.75277412074478	0.12609465662035	0.37828396986105
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	5/5317	10/18639	0.5	1.75277412074478	0.12609465662035	0.37828396986105
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	5/5317	10/18639	0.5	1.75277412074478	0.12609465662035	0.37828396986105
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	5/5317	10/18639	0.5	1.75277412074478	0.12609465662035	0.37828396986105
GO:0099122	RNA polymerase II C-terminal domain binding	5/5317	10/18639	0.5	1.75277412074478	0.12609465662035	0.37828396986105
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	5/5317	10/18639	0.5	1.75277412074478	0.12609465662035	0.37828396986105
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	5/5317	10/18639	0.5	1.75277412074478	0.12609465662035	0.37828396986105
GO:1905394	retromer complex binding	5/5317	10/18639	0.5	1.75277412074478	0.12609465662035	0.37828396986105
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	5/5317	10/18639	0.5	1.75277412074478	0.12609465662035	0.37828396986105
GO:0033218	amide binding	79/5317	247/18639	0.319838056680162	1.12120773715658	0.127569968316275	0.381876114306234
GO:0005125	cytokine activity	75/5317	234/18639	0.320512820512821	1.12357315432358	0.129978248024842	0.388239375622027
GO:0004722	protein serine/threonine phosphatase activity	35/5317	103/18639	0.339805825242718	1.19120571312752	0.132049245439636	0.393569768403602
GO:0030291	protein serine/threonine kinase inhibitor activity	17/5317	46/18639	0.369565217391304	1.29552869794179	0.135490979818143	0.398106897123563
GO:0008083	growth factor activity	53/5317	162/18639	0.327160493827161	1.14687689382066	0.136385741020486	0.398106897123563
GO:0004535	poly(A)-specific ribonuclease activity	6/5317	13/18639	0.461538461538462	1.61794534222595	0.136468958184278	0.398106897123563
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	6/5317	13/18639	0.461538461538462	1.61794534222595	0.136468958184278	0.398106897123563
GO:0005035	death receptor activity	6/5317	13/18639	0.461538461538462	1.61794534222595	0.136468958184278	0.398106897123563
GO:0008035	high-density lipoprotein particle binding	6/5317	13/18639	0.461538461538462	1.61794534222595	0.136468958184278	0.398106897123563
GO:0017154	semaphorin receptor activity	6/5317	13/18639	0.461538461538462	1.61794534222595	0.136468958184278	0.398106897123563
GO:0045159	myosin II binding	6/5317	13/18639	0.461538461538462	1.61794534222595	0.136468958184278	0.398106897123563
GO:0046974	histone H3K9 methyltransferase activity	6/5317	13/18639	0.461538461538462	1.61794534222595	0.136468958184278	0.398106897123563
GO:0140666	annealing activity	6/5317	13/18639	0.461538461538462	1.61794534222595	0.136468958184278	0.398106897123563
GO:0008200	ion channel inhibitor activity	16/5317	43/18639	0.372093023255814	1.30439004334495	0.13780326650807	0.399678184368411
GO:0030414	peptidase inhibitor activity	55/5317	169/18639	0.325443786982249	1.14085889515932	0.141182657668015	0.399678184368411
GO:0019213	deacetylase activity	14/5317	37/18639	0.378378378378378	1.326423658942	0.142068889606482	0.399678184368411
GO:0004707	MAP kinase activity	7/5317	16/18639	0.4375	1.53367735565168	0.142362342556934	0.399678184368411
GO:0004708	MAP kinase kinase activity	7/5317	16/18639	0.4375	1.53367735565168	0.142362342556934	0.399678184368411
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	7/5317	16/18639	0.4375	1.53367735565168	0.142362342556934	0.399678184368411
GO:0034450	ubiquitin-ubiquitin ligase activity	7/5317	16/18639	0.4375	1.53367735565168	0.142362342556934	0.399678184368411
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	13/5317	34/18639	0.382352941176471	1.34035668056954	0.143916284682911	0.399678184368411
GO:0140457	protein demethylase activity	12/5317	31/18639	0.387096774193548	1.35698641606048	0.145470305113246	0.399678184368411
GO:0015245	fatty acid transmembrane transporter activity	8/5317	19/18639	0.421052631578947	1.47602031220613	0.145532539505094	0.399678184368411
GO:0042800	histone H3K4 methyltransferase activity	8/5317	19/18639	0.421052631578947	1.47602031220613	0.145532539505094	0.399678184368411
GO:0140097	catalytic activity, acting on DNA	105/5317	336/18639	0.3125	1.09548382546549	0.145922603367235	0.399678184368411
GO:0036408	histone H3K14 acetyltransferase activity	11/5317	28/18639	0.392857142857143	1.37717966629947	0.146615736895501	0.399678184368411
GO:0046966	nuclear thyroid hormone receptor binding	11/5317	28/18639	0.392857142857143	1.37717966629947	0.146615736895501	0.399678184368411
GO:0050698	proteoglycan sulfotransferase activity	11/5317	28/18639	0.392857142857143	1.37717966629947	0.146615736895501	0.399678184368411
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	11/5317	28/18639	0.392857142857143	1.37717966629947	0.146615736895501	0.399678184368411
GO:0004407	histone deacetylase activity	9/5317	22/18639	0.409090909090909	1.434087916973	0.146948899570405	0.399678184368411
GO:0032931	histone H3K56 acetyltransferase activity	9/5317	22/18639	0.409090909090909	1.434087916973	0.146948899570405	0.399678184368411
GO:0033558	protein lysine deacetylase activity	9/5317	22/18639	0.409090909090909	1.434087916973	0.146948899570405	0.399678184368411
GO:0043992	histone H3K9 acetyltransferase activity	9/5317	22/18639	0.409090909090909	1.434087916973	0.146948899570405	0.399678184368411
GO:0043993	histone H3K18 acetyltransferase activity	9/5317	22/18639	0.409090909090909	1.434087916973	0.146948899570405	0.399678184368411
GO:0043994	histone H3K23 acetyltransferase activity	9/5317	22/18639	0.409090909090909	1.434087916973	0.146948899570405	0.399678184368411
GO:0043999	histone H2AK5 acetyltransferase activity	9/5317	22/18639	0.409090909090909	1.434087916973	0.146948899570405	0.399678184368411
GO:0044012	histone H2AK9 acetyltransferase activity	9/5317	22/18639	0.409090909090909	1.434087916973	0.146948899570405	0.399678184368411
GO:0044014	histone H2BK5 acetyltransferase activity	9/5317	22/18639	0.409090909090909	1.434087916973	0.146948899570405	0.399678184368411
GO:0044015	histone H2BK12 acetyltransferase activity	9/5317	22/18639	0.409090909090909	1.434087916973	0.146948899570405	0.399678184368411
GO:0044016	histone H3K4 acetyltransferase activity	9/5317	22/18639	0.409090909090909	1.434087916973	0.146948899570405	0.399678184368411
GO:0044017	histone H3K27 acetyltransferase activity	9/5317	22/18639	0.409090909090909	1.434087916973	0.146948899570405	0.399678184368411
GO:0044018	histone H3K36 acetyltransferase activity	9/5317	22/18639	0.409090909090909	1.434087916973	0.146948899570405	0.399678184368411
GO:0061133	endopeptidase activator activity	9/5317	22/18639	0.409090909090909	1.434087916973	0.146948899570405	0.399678184368411
GO:0140035	ubiquitin-like protein reader activity	9/5317	22/18639	0.409090909090909	1.434087916973	0.146948899570405	0.399678184368411
GO:0140908	histone H3K122 acetyltransferase activity	9/5317	22/18639	0.409090909090909	1.434087916973	0.146948899570405	0.399678184368411
GO:0015645	fatty acid ligase activity	10/5317	25/18639	0.4	1.40221929659582	0.147188618115295	0.399678184368411
GO:0120020	cholesterol transfer activity	10/5317	25/18639	0.4	1.40221929659582	0.147188618115295	0.399678184368411
GO:0120515	fatty acid-CoA ligase activity	10/5317	25/18639	0.4	1.40221929659582	0.147188618115295	0.399678184368411
GO:0140030	modification-dependent protein binding	56/5317	173/18639	0.323699421965318	1.13474393944171	0.149260206042	0.404503990338674
GO:0051018	protein kinase A binding	19/5317	53/18639	0.358490566037736	1.25670597336418	0.151603880833838	0.410046717058452
GO:0032813	tumor necrosis factor receptor superfamily binding	18/5317	50/18639	0.36	1.26199736693624	0.154977314415711	0.417527117661152
GO:0048020	CCR chemokine receptor binding	18/5317	50/18639	0.36	1.26199736693624	0.154977314415711	0.417527117661152
GO:0004540	RNA nuclease activity	40/5317	121/18639	0.330578512396694	1.15885892280647	0.157037559216793	0.42224971891169
GO:0008234	cysteine-type peptidase activity	60/5317	187/18639	0.320855614973262	1.12477483684157	0.158131523906003	0.424215090161711
GO:0043495	protein-membrane adaptor activity	17/5317	47/18639	0.361702127659574	1.26796425756005	0.158385983444656	0.424215090161711
GO:0001046	core promoter sequence-specific DNA binding	16/5317	44/18639	0.363636363636364	1.27474481508711	0.161815852060458	0.431718409186541
GO:0043014	alpha-tubulin binding	16/5317	44/18639	0.363636363636364	1.27474481508711	0.161815852060458	0.431718409186541
GO:0016877	ligase activity, forming carbon-sulfur bonds	15/5317	41/18639	0.365853658536585	1.28251764932545	0.165247523960383	0.439168467933397
GO:0042169	SH2 domain binding	15/5317	41/18639	0.365853658536585	1.28251764932545	0.165247523960383	0.439168467933397
GO:0043531	ADP binding	14/5317	38/18639	0.368421052631579	1.29151777318036	0.168654117147119	0.447356673668226
GO:0010485	histone H4 acetyltransferase activity	13/5317	35/18639	0.371428571428571	1.30206077541041	0.171998111530887	0.454471933160459
GO:0034061	DNA polymerase activity	13/5317	35/18639	0.371428571428571	1.30206077541041	0.171998111530887	0.454471933160459
GO:0140463	chromatin-protein adaptor activity	19/5317	54/18639	0.351851851851852	1.23343364052411	0.174255736878256	0.458790976519823
GO:0004181	metallocarboxypeptidase activity	11/5317	29/18639	0.379310344827586	1.32969071228914	0.178263537649651	0.458790976519823
GO:0010484	histone H3 acetyltransferase activity	11/5317	29/18639	0.379310344827586	1.32969071228914	0.178263537649651	0.458790976519823
GO:0005272	sodium channel activity	18/5317	51/18639	0.352941176470588	1.23725232052573	0.178666816100001	0.458790976519823
GO:0030544	Hsp70 protein binding	18/5317	51/18639	0.352941176470588	1.23725232052573	0.178666816100001	0.458790976519823
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	5/5317	11/18639	0.454545454545455	1.59343101885889	0.178975228103803	0.458790976519823
GO:0005114	type II transforming growth factor beta receptor binding	5/5317	11/18639	0.454545454545455	1.59343101885889	0.178975228103803	0.458790976519823
GO:0016176	superoxide-generating NADPH oxidase activator activity	5/5317	11/18639	0.454545454545455	1.59343101885889	0.178975228103803	0.458790976519823
GO:0019107	myristoyltransferase activity	5/5317	11/18639	0.454545454545455	1.59343101885889	0.178975228103803	0.458790976519823
GO:0032050	clathrin heavy chain binding	5/5317	11/18639	0.454545454545455	1.59343101885889	0.178975228103803	0.458790976519823
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	5/5317	11/18639	0.454545454545455	1.59343101885889	0.178975228103803	0.458790976519823
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	5/5317	11/18639	0.454545454545455	1.59343101885889	0.178975228103803	0.458790976519823
GO:0043522	leucine zipper domain binding	5/5317	11/18639	0.454545454545455	1.59343101885889	0.178975228103803	0.458790976519823
GO:0045294	alpha-catenin binding	5/5317	11/18639	0.454545454545455	1.59343101885889	0.178975228103803	0.458790976519823
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	5/5317	11/18639	0.454545454545455	1.59343101885889	0.178975228103803	0.458790976519823
GO:0048407	platelet-derived growth factor binding	5/5317	11/18639	0.454545454545455	1.59343101885889	0.178975228103803	0.458790976519823
GO:0008157	protein phosphatase 1 binding	10/5317	26/18639	0.384615384615385	1.34828778518829	0.180998018102193	0.461393834642696
GO:0015145	monosaccharide transmembrane transporter activity	10/5317	26/18639	0.384615384615385	1.34828778518829	0.180998018102193	0.461393834642696
GO:0019865	immunoglobulin binding	10/5317	26/18639	0.384615384615385	1.34828778518829	0.180998018102193	0.461393834642696
GO:0036121	double-stranded DNA helicase activity	17/5317	48/18639	0.354166666666667	1.24154833552755	0.183202516128797	0.463118602357753
GO:0070577	lysine-acetylated histone binding	9/5317	23/18639	0.391304347826087	1.37173626840896	0.183263175177669	0.463118602357753
GO:0005313	L-glutamate transmembrane transporter activity	6/5317	14/18639	0.428571428571429	1.50237781778124	0.183696971095324	0.463118602357753
GO:0032036	myosin heavy chain binding	6/5317	14/18639	0.428571428571429	1.50237781778124	0.183696971095324	0.463118602357753
GO:0042813	Wnt receptor activity	6/5317	14/18639	0.428571428571429	1.50237781778124	0.183696971095324	0.463118602357753
GO:0044548	S100 protein binding	6/5317	14/18639	0.428571428571429	1.50237781778124	0.183696971095324	0.463118602357753
GO:0008429	phosphatidylethanolamine binding	7/5317	17/18639	0.411764705882353	1.44346104061335	0.1851863286406	0.466018343502168
GO:0019905	syntaxin binding	21/5317	61/18639	0.344262295081967	1.20682808313575	0.188109981364307	0.472510263975426
GO:0035064	methylated histone binding	25/5317	74/18639	0.337837837837838	1.18430683834107	0.189687772875493	0.475604014472496
GO:0004402	histone acetyltransferase activity	15/5317	42/18639	0.357142857142857	1.2519815148177	0.192644638987527	0.481261334488841
GO:0048487	beta-tubulin binding	15/5317	42/18639	0.357142857142857	1.2519815148177	0.192644638987527	0.481261334488841
GO:0017116	single-stranded DNA helicase activity	20/5317	58/18639	0.344827586206897	1.20880973844468	0.193231176018346	0.481850518782591
GO:0016776	phosphotransferase activity, phosphate group as acceptor	14/5317	39/18639	0.358974358974359	1.25840193284241	0.197543216704658	0.49171083288442
GO:0005080	protein kinase C binding	18/5317	52/18639	0.346153846153846	1.21345900666946	0.204071092075027	0.507041013582435
GO:0035254	glutamate receptor binding	17/5317	49/18639	0.346938775510204	1.21621061439434	0.209815113829694	0.519281966970366
GO:0031072	heat shock protein binding	42/5317	131/18639	0.320610687022901	1.12391623009589	0.209855289343782	0.519281966970366
GO:0004866	endopeptidase inhibitor activity	51/5317	161/18639	0.316770186335404	1.1104531696644	0.210131567420323	0.519281966970366
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	11/5317	30/18639	0.366666666666667	1.28536768854617	0.212795701726019	0.523980813927509
GO:0051721	protein phosphatase 2A binding	11/5317	30/18639	0.366666666666667	1.28536768854617	0.212795701726019	0.523980813927509
GO:0035255	ionotropic glutamate receptor binding	10/5317	27/18639	0.37037037037037	1.29835120055169	0.217963215677155	0.535745005975691
GO:0004622	lysophospholipase activity	9/5317	24/18639	0.375	1.31458059055859	0.223068427773907	0.546338716152135
GO:0140033	acetylation-dependent protein binding	9/5317	24/18639	0.375	1.31458059055859	0.223068427773907	0.546338716152135
GO:0005123	death receptor binding	8/5317	21/18639	0.380952380952381	1.33544694913888	0.227985220104369	0.552326811592311
GO:0035613	RNA stem-loop binding	8/5317	21/18639	0.380952380952381	1.33544694913888	0.227985220104369	0.552326811592311
GO:0061891	calcium ion sensor activity	8/5317	21/18639	0.380952380952381	1.33544694913888	0.227985220104369	0.552326811592311
GO:0072542	protein phosphatase activator activity	8/5317	21/18639	0.380952380952381	1.33544694913888	0.227985220104369	0.552326811592311
GO:0004177	aminopeptidase activity	14/5317	40/18639	0.35	1.22694188452135	0.228522116447931	0.552326811592311
GO:0015144	carbohydrate transmembrane transporter activity	14/5317	40/18639	0.35	1.22694188452135	0.228522116447931	0.552326811592311
GO:0140767	enzyme-substrate adaptor activity	44/5317	139/18639	0.316546762589928	1.10966994694634	0.232140923638676	0.552326811592311
GO:0000900	mRNA regulatory element binding translation repressor activity	7/5317	18/18639	0.388888888888889	1.36326876057927	0.232497130852439	0.552326811592311
GO:0015280	ligand-gated sodium channel activity	7/5317	18/18639	0.388888888888889	1.36326876057927	0.232497130852439	0.552326811592311
GO:0098641	cadherin binding involved in cell-cell adhesion	7/5317	18/18639	0.388888888888889	1.36326876057927	0.232497130852439	0.552326811592311
GO:0140034	methylation-dependent protein binding	25/5317	76/18639	0.328947368421053	1.15314086891104	0.233791467733112	0.552326811592311
GO:0004467	long-chain fatty acid-CoA ligase activity	6/5317	15/18639	0.4	1.40221929659582	0.236213676208329	0.552326811592311
GO:0004559	alpha-mannosidase activity	6/5317	15/18639	0.4	1.40221929659582	0.236213676208329	0.552326811592311
GO:0005523	tropomyosin binding	6/5317	15/18639	0.4	1.40221929659582	0.236213676208329	0.552326811592311
GO:0010181	FMN binding	6/5317	15/18639	0.4	1.40221929659582	0.236213676208329	0.552326811592311
GO:0015556	C4-dicarboxylate transmembrane transporter activity	6/5317	15/18639	0.4	1.40221929659582	0.236213676208329	0.552326811592311
GO:0047372	monoacylglycerol lipase activity	6/5317	15/18639	0.4	1.40221929659582	0.236213676208329	0.552326811592311
GO:0050780	dopamine receptor binding	6/5317	15/18639	0.4	1.40221929659582	0.236213676208329	0.552326811592311
GO:0141050	histone H3K deacetylase activity	6/5317	15/18639	0.4	1.40221929659582	0.236213676208329	0.552326811592311
GO:0141051	histone H4K deacetylase activity	6/5317	15/18639	0.4	1.40221929659582	0.236213676208329	0.552326811592311
GO:0050660	flavin adenine dinucleotide binding	28/5317	86/18639	0.325581395348837	1.14134128792683	0.236220164962488	0.552326811592311
GO:0004000	adenosine deaminase activity	5/5317	12/18639	0.416666666666667	1.46064510062065	0.238376855366987	0.552326811592311
GO:0005095	GTPase inhibitor activity	5/5317	12/18639	0.416666666666667	1.46064510062065	0.238376855366987	0.552326811592311
GO:0005527	macrolide binding	5/5317	12/18639	0.416666666666667	1.46064510062065	0.238376855366987	0.552326811592311
GO:0008179	adenylate cyclase binding	5/5317	12/18639	0.416666666666667	1.46064510062065	0.238376855366987	0.552326811592311
GO:0015166	polyol transmembrane transporter activity	5/5317	12/18639	0.416666666666667	1.46064510062065	0.238376855366987	0.552326811592311
GO:0015368	calcium:monoatomic cation antiporter activity	5/5317	12/18639	0.416666666666667	1.46064510062065	0.238376855366987	0.552326811592311
GO:0016273	arginine N-methyltransferase activity	5/5317	12/18639	0.416666666666667	1.46064510062065	0.238376855366987	0.552326811592311
GO:0016274	protein-arginine N-methyltransferase activity	5/5317	12/18639	0.416666666666667	1.46064510062065	0.238376855366987	0.552326811592311
GO:0034452	dynactin binding	5/5317	12/18639	0.416666666666667	1.46064510062065	0.238376855366987	0.552326811592311
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	5/5317	12/18639	0.416666666666667	1.46064510062065	0.238376855366987	0.552326811592311
GO:1990459	transferrin receptor binding	5/5317	12/18639	0.416666666666667	1.46064510062065	0.238376855366987	0.552326811592311
GO:0019825	oxygen binding	12/5317	34/18639	0.352941176470588	1.23725232052573	0.242401183553146	0.560705768016873
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	20/5317	60/18639	0.333333333333333	1.16851608049652	0.244046367271655	0.563562535514713
GO:0061733	protein-lysine-acetyltransferase activity	16/5317	47/18639	0.340425531914894	1.1933781247624	0.245424084871471	0.56390082376823
GO:0061749	forked DNA-dependent helicase activity	16/5317	47/18639	0.340425531914894	1.1933781247624	0.245424084871471	0.56390082376823
GO:1990518	single-stranded 3'-5' DNA helicase activity	16/5317	47/18639	0.340425531914894	1.1933781247624	0.245424084871471	0.56390082376823
GO:0003689	DNA clamp loader activity	50/5317	160/18639	0.3125	1.09548382546549	0.246690361954441	0.565864035601673
GO:0005164	tumor necrosis factor receptor binding	11/5317	31/18639	0.354838709677419	1.2439042147221	0.249824669863045	0.571660477376765
GO:0048306	calcium-dependent protein binding	26/5317	80/18639	0.325	1.13930317848411	0.250049451894786	0.571660477376765
GO:0051119	sugar transmembrane transporter activity	10/5317	28/18639	0.357142857142857	1.2519815148177	0.257600703889186	0.586970758115657
GO:0097718	disordered domain specific binding	10/5317	28/18639	0.357142857142857	1.2519815148177	0.257600703889186	0.586970758115657
GO:0003924	GTPase activity	100/5317	331/18639	0.302114803625378	1.05907801857691	0.264731094255566	0.601551281138794
GO:0003678	DNA helicase activity	24/5317	74/18639	0.324324324324324	1.13693456480743	0.265096892461133	0.601551281138794
GO:0015271	outward rectifier potassium channel activity	9/5317	25/18639	0.36	1.26199736693624	0.265750820706876	0.601551281138794
GO:0019211	phosphatase activator activity	9/5317	25/18639	0.36	1.26199736693624	0.265750820706876	0.601551281138794
GO:0030246	carbohydrate binding	85/5317	280/18639	0.303571428571429	1.06418428759505	0.266765847041528	0.602855713544505
GO:0140658	ATP-dependent chromatin remodeler activity	49/5317	158/18639	0.310126582278481	1.0871636951455	0.269490901425872	0.60801395494113
GO:0140299	molecular sensor activity	23/5317	71/18639	0.323943661971831	1.13560013456704	0.273135351797255	0.614807146263922
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	8/5317	22/18639	0.363636363636364	1.27474481508711	0.27429168898092	0.614807146263922
GO:0140517	protein-RNA adaptor activity	8/5317	22/18639	0.363636363636364	1.27474481508711	0.27429168898092	0.614807146263922
GO:0140784	metal ion sensor activity	8/5317	22/18639	0.363636363636364	1.27474481508711	0.27429168898092	0.614807146263922
GO:0009378	four-way junction helicase activity	16/5317	48/18639	0.333333333333333	1.16851608049652	0.276534869242808	0.615816710436983
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	16/5317	48/18639	0.333333333333333	1.16851608049652	0.276534869242808	0.615816710436983
GO:0016879	ligase activity, forming carbon-nitrogen bonds	16/5317	48/18639	0.333333333333333	1.16851608049652	0.276534869242808	0.615816710436983
GO:0043138	3'-5' DNA helicase activity	16/5317	48/18639	0.333333333333333	1.16851608049652	0.276534869242808	0.615816710436983
GO:0061631	ubiquitin conjugating enzyme activity	12/5317	35/18639	0.342857142857143	1.20190225422499	0.279133221129977	0.620597161541405
GO:0042577	lipid phosphatase activity	7/5317	19/18639	0.368421052631579	1.29151777318036	0.283226475805057	0.626655680766745
GO:0050145	nucleoside monophosphate kinase activity	7/5317	19/18639	0.368421052631579	1.29151777318036	0.283226475805057	0.626655680766745
GO:0140036	ubiquitin-modified protein reader activity	7/5317	19/18639	0.368421052631579	1.29151777318036	0.283226475805057	0.626655680766745
GO:0043425	bHLH transcription factor binding	11/5317	32/18639	0.34375	1.20503220801204	0.288899873971159	0.635963023057681
GO:0019003	GDP binding	24/5317	75/18639	0.32	1.12177543727666	0.290466068111471	0.635963023057681
GO:0005521	lamin binding	6/5317	16/18639	0.375	1.31458059055859	0.292524476399166	0.635963023057681
GO:0008142	oxysterol binding	6/5317	16/18639	0.375	1.31458059055859	0.292524476399166	0.635963023057681
GO:0008296	3'-5'-DNA exonuclease activity	6/5317	16/18639	0.375	1.31458059055859	0.292524476399166	0.635963023057681
GO:0015923	mannosidase activity	6/5317	16/18639	0.375	1.31458059055859	0.292524476399166	0.635963023057681
GO:0016722	oxidoreductase activity, acting on metal ions	6/5317	16/18639	0.375	1.31458059055859	0.292524476399166	0.635963023057681
GO:0030275	LRR domain binding	6/5317	16/18639	0.375	1.31458059055859	0.292524476399166	0.635963023057681
GO:0031435	mitogen-activated protein kinase kinase kinase binding	6/5317	16/18639	0.375	1.31458059055859	0.292524476399166	0.635963023057681
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	6/5317	16/18639	0.375	1.31458059055859	0.292524476399166	0.635963023057681
GO:0055102	lipase inhibitor activity	6/5317	16/18639	0.375	1.31458059055859	0.292524476399166	0.635963023057681
GO:0042056	chemoattractant activity	14/5317	42/18639	0.333333333333333	1.16851608049652	0.295674427112893	0.641795675913295
GO:0042379	chemokine receptor binding	23/5317	72/18639	0.319444444444444	1.11982791047583	0.299386779530658	0.648828761948145
GO:0061775	cohesin loader activity	47/5317	153/18639	0.30718954248366	1.07686776045758	0.300696797361574	0.650537940407356
GO:0070700	BMP receptor binding	5/5317	13/18639	0.384615384615385	1.34828778518829	0.302069291106181	0.650537940407356
GO:0071837	HMG box domain binding	5/5317	13/18639	0.384615384615385	1.34828778518829	0.302069291106181	0.650537940407356
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	5/5317	13/18639	0.384615384615385	1.34828778518829	0.302069291106181	0.650537940407356
GO:0019787	ubiquitin-like protein transferase activity	142/5317	479/18639	0.296450939457203	1.03922306950212	0.307362645472825	0.656464502368976
GO:0050750	low-density lipoprotein particle receptor binding	9/5317	26/18639	0.346153846153846	1.21345900666946	0.31061995149759	0.656464502368976
GO:0004862	cAMP-dependent protein kinase inhibitor activity	4/5317	10/18639	0.4	1.40221929659582	0.311510084093575	0.656464502368976
GO:0005528	FK506 binding	4/5317	10/18639	0.4	1.40221929659582	0.311510084093575	0.656464502368976
GO:0008140	cAMP response element binding protein binding	4/5317	10/18639	0.4	1.40221929659582	0.311510084093575	0.656464502368976
GO:0015924	mannosyl-oligosaccharide mannosidase activity	4/5317	10/18639	0.4	1.40221929659582	0.311510084093575	0.656464502368976
GO:0016427	tRNA (cytidine) methyltransferase activity	4/5317	10/18639	0.4	1.40221929659582	0.311510084093575	0.656464502368976
GO:0030957	Tat protein binding	4/5317	10/18639	0.4	1.40221929659582	0.311510084093575	0.656464502368976
GO:0031419	cobalamin binding	4/5317	10/18639	0.4	1.40221929659582	0.311510084093575	0.656464502368976
GO:0031956	medium-chain fatty acid-CoA ligase activity	4/5317	10/18639	0.4	1.40221929659582	0.311510084093575	0.656464502368976
GO:0031957	very long-chain fatty acid-CoA ligase activity	4/5317	10/18639	0.4	1.40221929659582	0.311510084093575	0.656464502368976
GO:0043422	protein kinase B binding	4/5317	10/18639	0.4	1.40221929659582	0.311510084093575	0.656464502368976
GO:0051864	histone H3K36 demethylase activity	4/5317	10/18639	0.4	1.40221929659582	0.311510084093575	0.656464502368976
GO:0070513	death domain binding	4/5317	10/18639	0.4	1.40221929659582	0.311510084093575	0.656464502368976
GO:0016298	lipase activity	40/5317	130/18639	0.307692307692308	1.07863022815063	0.315116516437966	0.661121804153476
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	40/5317	130/18639	0.307692307692308	1.07863022815063	0.315116516437966	0.661121804153476
GO:0140713	histone chaperone activity	50/5317	164/18639	0.304878048780488	1.06876470777121	0.31516359659427	0.661121804153476
GO:0004869	cysteine-type endopeptidase inhibitor activity	12/5317	36/18639	0.333333333333333	1.16851608049652	0.317425787851066	0.664852183700252
GO:0004842	ubiquitin-protein transferase activity	133/5317	449/18639	0.296213808463252	1.03839179536328	0.318139168752392	0.6653321428703
GO:0032182	ubiquitin-like protein binding	37/5317	120/18639	0.308333333333333	1.08087737445928	0.318756480423222	0.66561003662843
GO:0051213	dioxygenase activity	29/5317	93/18639	0.311827956989247	1.09312794627094	0.320481688152754	0.668197025071144
GO:0004518	nuclease activity	63/5317	209/18639	0.301435406698565	1.05669635987484	0.325549272575878	0.674029567760018
GO:0043130	ubiquitin binding	31/5317	100/18639	0.31	1.08671995486176	0.326088850799002	0.674029567760018
GO:0043539	protein serine/threonine kinase activator activity	23/5317	73/18639	0.315068493150685	1.10448780211315	0.326410352991092	0.674029567760018
GO:0000510	H3-H4 histone complex chaperone activity	46/5317	151/18639	0.304635761589404	1.06791535833457	0.326713021927345	0.674029567760018
GO:0140584	chromatin extrusion motor activity	46/5317	151/18639	0.304635761589404	1.06791535833457	0.326713021927345	0.674029567760018
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	46/5317	151/18639	0.304635761589404	1.06791535833457	0.326713021927345	0.674029567760018
GO:0140849	ATP-dependent H2AZ histone chaperone activity	46/5317	151/18639	0.304635761589404	1.06791535833457	0.326713021927345	0.674029567760018
GO:0019239	deaminase activity	11/5317	33/18639	0.333333333333333	1.16851608049652	0.329528907216089	0.67881966793839
GO:0005544	calcium-dependent phospholipid binding	17/5317	53/18639	0.320754716981132	1.12442113406269	0.330644491536449	0.679081511765442
GO:0034212	protein N-acetyltransferase activity	17/5317	53/18639	0.320754716981132	1.12442113406269	0.330644491536449	0.679081511765442
GO:0010851	cyclase regulator activity	7/5317	20/18639	0.35	1.22694188452135	0.336225501026356	0.688485601207471
GO:0016505	peptidase activator activity involved in apoptotic process	7/5317	20/18639	0.35	1.22694188452135	0.336225501026356	0.688485601207471
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	19/5317	60/18639	0.316666666666667	1.11009027647169	0.339732923061011	0.694632494472961
GO:0035925	mRNA 3'-UTR AU-rich region binding	10/5317	30/18639	0.333333333333333	1.16851608049652	0.342637809896717	0.699530981869375
GO:0032451	demethylase activity	13/5317	40/18639	0.325	1.13930317848411	0.343570284423623	0.70010288340196
GO:0031490	chromatin DNA binding	39/5317	128/18639	0.3046875	1.06809672982885	0.343937006038081	0.70010288340196
GO:0015616	DNA translocase activity	46/5317	152/18639	0.302631578947368	1.06088959939816	0.345811499524766	0.70112455423079
GO:0140674	ATP-dependent histone chaperone activity	46/5317	152/18639	0.302631578947368	1.06088959939816	0.345811499524766	0.70112455423079
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	21/5317	67/18639	0.313432835820896	1.09875392643703	0.347432674967943	0.70112455423079
GO:0004527	exonuclease activity	26/5317	84/18639	0.30952380952381	1.08505064617534	0.349381871927123	0.70112455423079
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	6/5317	17/18639	0.352941176470588	1.23725232052573	0.351072556994748	0.70112455423079
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	6/5317	17/18639	0.352941176470588	1.23725232052573	0.351072556994748	0.70112455423079
GO:0031489	myosin V binding	6/5317	17/18639	0.352941176470588	1.23725232052573	0.351072556994748	0.70112455423079
GO:0032183	SUMO binding	6/5317	17/18639	0.352941176470588	1.23725232052573	0.351072556994748	0.70112455423079
GO:0038191	neuropilin binding	6/5317	17/18639	0.352941176470588	1.23725232052573	0.351072556994748	0.70112455423079
GO:0045125	bioactive lipid receptor activity	6/5317	17/18639	0.352941176470588	1.23725232052573	0.351072556994748	0.70112455423079
GO:0048038	quinone binding	6/5317	17/18639	0.352941176470588	1.23725232052573	0.351072556994748	0.70112455423079
GO:0070403	NAD+ binding	6/5317	17/18639	0.352941176470588	1.23725232052573	0.351072556994748	0.70112455423079
GO:1990226	histone methyltransferase binding	6/5317	17/18639	0.352941176470588	1.23725232052573	0.351072556994748	0.70112455423079
GO:0070851	growth factor receptor binding	42/5317	139/18639	0.302158273381295	1.05923040390332	0.359404424073027	0.716722320284962
GO:0140104	molecular carrier activity	74/5317	249/18639	0.29718875502008	1.04180951755111	0.360357616374361	0.717581688258511
GO:0004197	cysteine-type endopeptidase activity	27/5317	88/18639	0.306818181818182	1.07556593772975	0.364944304037445	0.721629112436718
GO:0030547	signaling receptor inhibitor activity	14/5317	44/18639	0.318181818181818	1.11540171320122	0.367659590760018	0.721629112436718
GO:0004065	arylsulfatase activity	5/5317	14/18639	0.357142857142857	1.2519815148177	0.367831691112213	0.721629112436718
GO:0008195	phosphatidate phosphatase activity	5/5317	14/18639	0.357142857142857	1.2519815148177	0.367831691112213	0.721629112436718
GO:0008331	high voltage-gated calcium channel activity	5/5317	14/18639	0.357142857142857	1.2519815148177	0.367831691112213	0.721629112436718
GO:0008559	ABC-type xenobiotic transporter activity	5/5317	14/18639	0.357142857142857	1.2519815148177	0.367831691112213	0.721629112436718
GO:0019763	immunoglobulin receptor activity	5/5317	14/18639	0.357142857142857	1.2519815148177	0.367831691112213	0.721629112436718
GO:0070742	C2H2 zinc finger domain binding	5/5317	14/18639	0.357142857142857	1.2519815148177	0.367831691112213	0.721629112436718
GO:1901474	azole transmembrane transporter activity	5/5317	14/18639	0.357142857142857	1.2519815148177	0.367831691112213	0.721629112436718
GO:1990825	sequence-specific mRNA binding	5/5317	14/18639	0.357142857142857	1.2519815148177	0.367831691112213	0.721629112436718
GO:0016779	nucleotidyltransferase activity	41/5317	136/18639	0.301470588235294	1.05681969044906	0.368167400158762	0.721629112436718
GO:0008175	tRNA methyltransferase activity	11/5317	34/18639	0.323529411764706	1.13414796048192	0.371198688098366	0.726419437562464
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	8/5317	24/18639	0.333333333333333	1.16851608049652	0.372726130627028	0.726419437562464
GO:0070840	dynein complex binding	8/5317	24/18639	0.333333333333333	1.16851608049652	0.372726130627028	0.726419437562464
GO:0140612	DNA damage sensor activity	8/5317	24/18639	0.333333333333333	1.16851608049652	0.372726130627028	0.726419437562464
GO:0005048	signal sequence binding	16/5317	51/18639	0.313725490196078	1.09977984046731	0.376243084583587	0.732235124954459
GO:0016755	aminoacyltransferase activity	145/5317	496/18639	0.292338709677419	1.024807449629	0.378457497654014	0.732883816869696
GO:0061650	ubiquitin-like protein conjugating enzyme activity	13/5317	41/18639	0.317073170731707	1.11151529608206	0.381752733003958	0.732883816869696
GO:0140828	metal cation:monoatomic cation antiporter activity	13/5317	41/18639	0.317073170731707	1.11151529608206	0.381752733003958	0.732883816869696
GO:0005310	dicarboxylic acid transmembrane transporter activity	10/5317	31/18639	0.32258064516129	1.13082201338373	0.386834543246086	0.732883816869696
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	4/5317	11/18639	0.363636363636364	1.27474481508711	0.387244287516302	0.732883816869696
GO:0001851	complement component C3b binding	4/5317	11/18639	0.363636363636364	1.27474481508711	0.387244287516302	0.732883816869696
GO:0004143	ATP-dependent diacylglycerol kinase activity	4/5317	11/18639	0.363636363636364	1.27474481508711	0.387244287516302	0.732883816869696
GO:0005225	volume-sensitive anion channel activity	4/5317	11/18639	0.363636363636364	1.27474481508711	0.387244287516302	0.732883816869696
GO:0005536	D-glucose binding	4/5317	11/18639	0.363636363636364	1.27474481508711	0.387244287516302	0.732883816869696
GO:0008046	axon guidance receptor activity	4/5317	11/18639	0.363636363636364	1.27474481508711	0.387244287516302	0.732883816869696
GO:0008172	S-methyltransferase activity	4/5317	11/18639	0.363636363636364	1.27474481508711	0.387244287516302	0.732883816869696
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	4/5317	11/18639	0.363636363636364	1.27474481508711	0.387244287516302	0.732883816869696
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	4/5317	11/18639	0.363636363636364	1.27474481508711	0.387244287516302	0.732883816869696
GO:0019203	carbohydrate phosphatase activity	4/5317	11/18639	0.363636363636364	1.27474481508711	0.387244287516302	0.732883816869696
GO:0019864	IgG binding	4/5317	11/18639	0.363636363636364	1.27474481508711	0.387244287516302	0.732883816869696
GO:0032404	mismatch repair complex binding	4/5317	11/18639	0.363636363636364	1.27474481508711	0.387244287516302	0.732883816869696
GO:0032794	GTPase activating protein binding	4/5317	11/18639	0.363636363636364	1.27474481508711	0.387244287516302	0.732883816869696
GO:0035252	UDP-xylosyltransferase activity	4/5317	11/18639	0.363636363636364	1.27474481508711	0.387244287516302	0.732883816869696
GO:0042285	xylosyltransferase activity	4/5317	11/18639	0.363636363636364	1.27474481508711	0.387244287516302	0.732883816869696
GO:0047676	arachidonate-CoA ligase activity	4/5317	11/18639	0.363636363636364	1.27474481508711	0.387244287516302	0.732883816869696
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	7/5317	21/18639	0.333333333333333	1.16851608049652	0.39034564148735	0.734705358087149
GO:0001846	opsonin binding	7/5317	21/18639	0.333333333333333	1.16851608049652	0.39034564148735	0.734705358087149
GO:0008373	sialyltransferase activity	7/5317	21/18639	0.333333333333333	1.16851608049652	0.39034564148735	0.734705358087149
GO:0010314	phosphatidylinositol-5-phosphate binding	7/5317	21/18639	0.333333333333333	1.16851608049652	0.39034564148735	0.734705358087149
GO:0005109	frizzled binding	12/5317	38/18639	0.315789473684211	1.1070152341546	0.396938646415551	0.745073360894763
GO:0042162	telomeric DNA binding	12/5317	38/18639	0.315789473684211	1.1070152341546	0.396938646415551	0.745073360894763
GO:0008186	ATP-dependent activity, acting on RNA	24/5317	79/18639	0.30379746835443	1.06497668095885	0.39847689575316	0.746940320279457
GO:0015179	L-amino acid transmembrane transporter activity	19/5317	62/18639	0.306451612903226	1.07428091271454	0.402053934090351	0.752618672261775
GO:0046875	ephrin receptor binding	9/5317	28/18639	0.321428571428571	1.12678336333593	0.40400771623242	0.754339789139447
GO:0042605	peptide antigen binding	14/5317	45/18639	0.311111111111111	1.09061500846342	0.404620396357913	0.754339789139447
GO:0051539	4 iron, 4 sulfur cluster binding	14/5317	45/18639	0.311111111111111	1.09061500846342	0.404620396357913	0.754339789139447
GO:0032393	MHC class I receptor activity	6/5317	18/18639	0.333333333333333	1.16851608049652	0.410360270065903	0.764004080041396
GO:0004520	DNA endonuclease activity	13/5317	42/18639	0.30952380952381	1.08505064617534	0.420339559782711	0.776094366278837
GO:0000030	mannosyltransferase activity	8/5317	25/18639	0.32	1.12177543727666	0.423067452942394	0.776094366278837
GO:0001848	complement binding	8/5317	25/18639	0.32	1.12177543727666	0.423067452942394	0.776094366278837
GO:0005251	delayed rectifier potassium channel activity	8/5317	25/18639	0.32	1.12177543727666	0.423067452942394	0.776094366278837
GO:0008139	nuclear localization sequence binding	8/5317	25/18639	0.32	1.12177543727666	0.423067452942394	0.776094366278837
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	8/5317	25/18639	0.32	1.12177543727666	0.423067452942394	0.776094366278837
GO:0017025	TBP-class protein binding	8/5317	25/18639	0.32	1.12177543727666	0.423067452942394	0.776094366278837
GO:0017056	structural constituent of nuclear pore	8/5317	25/18639	0.32	1.12177543727666	0.423067452942394	0.776094366278837
GO:0019706	protein-cysteine S-palmitoyltransferase activity	8/5317	25/18639	0.32	1.12177543727666	0.423067452942394	0.776094366278837
GO:0019707	protein-cysteine S-acyltransferase activity	8/5317	25/18639	0.32	1.12177543727666	0.423067452942394	0.776094366278837
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	8/5317	25/18639	0.32	1.12177543727666	0.423067452942394	0.776094366278837
GO:0034483	heparan sulfate sulfotransferase activity	5/5317	15/18639	0.333333333333333	1.16851608049652	0.433640698564155	0.793371930528827
GO:0061578	K63-linked deubiquitinase activity	5/5317	15/18639	0.333333333333333	1.16851608049652	0.433640698564155	0.793371930528827
GO:0016782	transferase activity, transferring sulphur-containing groups	21/5317	70/18639	0.3	1.05166447244687	0.43668007327134	0.79787024025907
GO:0003724	RNA helicase activity	23/5317	77/18639	0.298701298701299	1.04711181239299	0.439268734006435	0.800726691396134
GO:0140597	protein carrier chaperone	55/5317	188/18639	0.292553191489362	1.02555932596769	0.439408970387689	0.800726691396134
GO:0008146	sulfotransferase activity	16/5317	53/18639	0.30188679245283	1.05827871441194	0.445327880252939	0.810437758235151
GO:0003785	actin monomer binding	9/5317	29/18639	0.310344827586207	1.08792876460021	0.45110049030909	0.818774205660093
GO:0016417	S-acyltransferase activity	9/5317	29/18639	0.310344827586207	1.08792876460021	0.45110049030909	0.818774205660093
GO:0004620	phospholipase activity	32/5317	109/18639	0.293577981651376	1.02915177731804	0.459618004873327	0.820628171971511
GO:0000340	RNA 7-methylguanosine cap binding	4/5317	12/18639	0.333333333333333	1.16851608049652	0.461678003590959	0.820628171971511
GO:0003995	acyl-CoA dehydrogenase activity	4/5317	12/18639	0.333333333333333	1.16851608049652	0.461678003590959	0.820628171971511
GO:0004126	cytidine deaminase activity	4/5317	12/18639	0.333333333333333	1.16851608049652	0.461678003590959	0.820628171971511
GO:0004875	complement receptor activity	4/5317	12/18639	0.333333333333333	1.16851608049652	0.461678003590959	0.820628171971511
GO:0005247	voltage-gated chloride channel activity	4/5317	12/18639	0.333333333333333	1.16851608049652	0.461678003590959	0.820628171971511
GO:0008603	cAMP-dependent protein kinase regulator activity	4/5317	12/18639	0.333333333333333	1.16851608049652	0.461678003590959	0.820628171971511
GO:0016840	carbon-nitrogen lyase activity	4/5317	12/18639	0.333333333333333	1.16851608049652	0.461678003590959	0.820628171971511
GO:0035197	siRNA binding	4/5317	12/18639	0.333333333333333	1.16851608049652	0.461678003590959	0.820628171971511
GO:0043047	single-stranded telomeric DNA binding	4/5317	12/18639	0.333333333333333	1.16851608049652	0.461678003590959	0.820628171971511
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	4/5317	12/18639	0.333333333333333	1.16851608049652	0.461678003590959	0.820628171971511
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	4/5317	12/18639	0.333333333333333	1.16851608049652	0.461678003590959	0.820628171971511
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	4/5317	12/18639	0.333333333333333	1.16851608049652	0.461678003590959	0.820628171971511
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	4/5317	12/18639	0.333333333333333	1.16851608049652	0.461678003590959	0.820628171971511
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	4/5317	12/18639	0.333333333333333	1.16851608049652	0.461678003590959	0.820628171971511
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	4/5317	12/18639	0.333333333333333	1.16851608049652	0.461678003590959	0.820628171971511
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	6/5317	19/18639	0.315789473684211	1.1070152341546	0.4690374058786	0.82622743035538
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	6/5317	19/18639	0.315789473684211	1.1070152341546	0.4690374058786	0.82622743035538
GO:0008301	DNA binding, bending	6/5317	19/18639	0.315789473684211	1.1070152341546	0.4690374058786	0.82622743035538
GO:0016918	retinal binding	6/5317	19/18639	0.315789473684211	1.1070152341546	0.4690374058786	0.82622743035538
GO:0022821	solute:potassium antiporter activity	6/5317	19/18639	0.315789473684211	1.1070152341546	0.4690374058786	0.82622743035538
GO:0030506	ankyrin binding	6/5317	19/18639	0.315789473684211	1.1070152341546	0.4690374058786	0.82622743035538
GO:0046624	sphingolipid transporter activity	6/5317	19/18639	0.315789473684211	1.1070152341546	0.4690374058786	0.82622743035538
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	8/5317	26/18639	0.307692307692308	1.07863022815063	0.473044120251195	0.829033955644313
GO:0008198	ferrous iron binding	8/5317	26/18639	0.307692307692308	1.07863022815063	0.473044120251195	0.829033955644313
GO:0051139	metal cation:proton antiporter activity	8/5317	26/18639	0.307692307692308	1.07863022815063	0.473044120251195	0.829033955644313
GO:0097602	cullin family protein binding	8/5317	26/18639	0.307692307692308	1.07863022815063	0.473044120251195	0.829033955644313
GO:0019956	chemokine binding	10/5317	33/18639	0.303030303030303	1.06228734590593	0.475620473655819	0.832487300386109
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	12/5317	40/18639	0.3	1.05166447244687	0.477435573989252	0.833540633622912
GO:0071949	FAD binding	12/5317	40/18639	0.3	1.05166447244687	0.477435573989252	0.833540633622912
GO:0140359	ABC-type transporter activity	14/5317	47/18639	0.297872340425532	1.0442058591671	0.47879055566666	0.834845461276639
GO:0051287	NAD binding	16/5317	54/18639	0.296296296296296	1.03868096044135	0.479843249922211	0.835620564503318
GO:0005262	calcium channel activity	38/5317	131/18639	0.290076335877863	1.01687658913438	0.484403452271654	0.842192936264496
GO:0046906	tetrapyrrole binding	44/5317	152/18639	0.289473684210526	1.01476396464172	0.484843240600594	0.842192936264496
GO:0120013	lipid transfer activity	19/5317	65/18639	0.292307692307692	1.0246987167431	0.49673845097304	0.851750703540373
GO:0160215	deacylase activity	19/5317	65/18639	0.292307692307692	1.0246987167431	0.49673845097304	0.851750703540373
GO:0016830	carbon-carbon lyase activity	15/5317	51/18639	0.294117647058824	1.03104360043811	0.497066470452245	0.851750703540373
GO:0015215	nucleotide transmembrane transporter activity	9/5317	30/18639	0.3	1.05166447244687	0.497584496200107	0.851750703540373
GO:0022839	monoatomic ion-gated channel activity	9/5317	30/18639	0.3	1.05166447244687	0.497584496200107	0.851750703540373
GO:0048019	receptor antagonist activity	9/5317	30/18639	0.3	1.05166447244687	0.497584496200107	0.851750703540373
GO:0031681	G-protein beta-subunit binding	7/5317	23/18639	0.304347826086957	1.0669059865403	0.497732118961217	0.851750703540373
GO:0015385	sodium:proton antiporter activity	5/5317	16/18639	0.3125	1.09548382546549	0.497784435911877	0.851750703540373
GO:0015562	efflux transmembrane transporter activity	5/5317	16/18639	0.3125	1.09548382546549	0.497784435911877	0.851750703540373
GO:0022841	potassium ion leak channel activity	5/5317	16/18639	0.3125	1.09548382546549	0.497784435911877	0.851750703540373
GO:0043023	ribosomal large subunit binding	5/5317	16/18639	0.3125	1.09548382546549	0.497784435911877	0.851750703540373
GO:0097027	ubiquitin-protein transferase activator activity	5/5317	16/18639	0.3125	1.09548382546549	0.497784435911877	0.851750703540373
GO:0001530	lipopolysaccharide binding	12/5317	41/18639	0.292682926829268	1.02601411946036	0.517028473707304	0.883578511037109
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	35/5317	122/18639	0.286885245901639	1.00569006927979	0.518531779811707	0.884967745700667
GO:0008376	acetylgalactosaminyltransferase activity	10/5317	34/18639	0.294117647058824	1.03104360043811	0.519129550971425	0.884967745700667
GO:0001972	retinoic acid binding	6/5317	20/18639	0.3	1.05166447244687	0.525956793672419	0.890283816737245
GO:0061608	nuclear import signal receptor activity	6/5317	20/18639	0.3	1.05166447244687	0.525956793672419	0.890283816737245
GO:0140664	ATP-dependent DNA damage sensor activity	6/5317	20/18639	0.3	1.05166447244687	0.525956793672419	0.890283816737245
GO:0015085	calcium ion transmembrane transporter activity	42/5317	147/18639	0.285714285714286	1.00158521185416	0.526532830144313	0.890283816737245
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	17/5317	59/18639	0.288135593220339	1.01007322212411	0.529775693303096	0.890283816737245
GO:0070888	E-box binding	17/5317	59/18639	0.288135593220339	1.01007322212411	0.529775693303096	0.890283816737245
GO:0005172	vascular endothelial growth factor receptor binding	4/5317	13/18639	0.307692307692308	1.07863022815063	0.532615209139749	0.890283816737245
GO:0005338	nucleotide-sugar transmembrane transporter activity	4/5317	13/18639	0.307692307692308	1.07863022815063	0.532615209139749	0.890283816737245
GO:0019855	calcium channel inhibitor activity	4/5317	13/18639	0.307692307692308	1.07863022815063	0.532615209139749	0.890283816737245
GO:0035325	Toll-like receptor binding	4/5317	13/18639	0.307692307692308	1.07863022815063	0.532615209139749	0.890283816737245
GO:0039706	co-receptor binding	4/5317	13/18639	0.307692307692308	1.07863022815063	0.532615209139749	0.890283816737245
GO:0061459	L-arginine transmembrane transporter activity	4/5317	13/18639	0.307692307692308	1.07863022815063	0.532615209139749	0.890283816737245
GO:0089720	caspase binding	4/5317	13/18639	0.307692307692308	1.07863022815063	0.532615209139749	0.890283816737245
GO:0097157	pre-mRNA intronic binding	4/5317	13/18639	0.307692307692308	1.07863022815063	0.532615209139749	0.890283816737245
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	4/5317	13/18639	0.307692307692308	1.07863022815063	0.532615209139749	0.890283816737245
GO:0140852	histone ubiquitin ligase activity	4/5317	13/18639	0.307692307692308	1.07863022815063	0.532615209139749	0.890283816737245
GO:0005501	retinoid binding	11/5317	38/18639	0.289473684210526	1.01476396464172	0.53834740526126	0.897681231588558
GO:0019840	isoprenoid binding	11/5317	38/18639	0.289473684210526	1.01476396464172	0.53834740526126	0.897681231588558
GO:0019212	phosphatase inhibitor activity	16/5317	56/18639	0.285714285714286	1.00158521185416	0.547573734151766	0.906980658264588
GO:0030170	pyridoxal phosphate binding	16/5317	56/18639	0.285714285714286	1.00158521185416	0.547573734151766	0.906980658264588
GO:0170055	lipid transmembrane transporter activity	16/5317	56/18639	0.285714285714286	1.00158521185416	0.547573734151766	0.906980658264588
GO:0004867	serine-type endopeptidase inhibitor activity	27/5317	95/18639	0.284210526315789	0.996313710739139	0.547983463886272	0.906980658264588
GO:0005315	phosphate transmembrane transporter activity	7/5317	24/18639	0.291666666666667	1.02245157043446	0.549205172981177	0.906980658264588
GO:0019957	C-C chemokine binding	7/5317	24/18639	0.291666666666667	1.02245157043446	0.549205172981177	0.906980658264588
GO:0030552	cAMP binding	7/5317	24/18639	0.291666666666667	1.02245157043446	0.549205172981177	0.906980658264588
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	7/5317	24/18639	0.291666666666667	1.02245157043446	0.549205172981177	0.906980658264588
GO:0004519	endonuclease activity	36/5317	127/18639	0.283464566929134	0.993698714123025	0.551635269970125	0.908814633873343
GO:0015101	organic cation transmembrane transporter activity	23/5317	81/18639	0.283950617283951	0.995402587089629	0.552536988309061	0.908814633873343
GO:0030971	receptor tyrosine kinase binding	23/5317	81/18639	0.283950617283951	0.995402587089629	0.552536988309061	0.908814633873343
GO:0003684	damaged DNA binding	21/5317	74/18639	0.283783783783784	0.994817744206497	0.555261663589023	0.908814633873343
GO:0005092	GDP-dissociation inhibitor activity	5/5317	17/18639	0.294117647058824	1.03104360043811	0.558914385460681	0.908814633873343
GO:0008484	sulfuric ester hydrolase activity	5/5317	17/18639	0.294117647058824	1.03104360043811	0.558914385460681	0.908814633873343
GO:0009881	photoreceptor activity	5/5317	17/18639	0.294117647058824	1.03104360043811	0.558914385460681	0.908814633873343
GO:0016805	dipeptidase activity	5/5317	17/18639	0.294117647058824	1.03104360043811	0.558914385460681	0.908814633873343
GO:0017110	nucleoside diphosphate phosphatase activity	5/5317	17/18639	0.294117647058824	1.03104360043811	0.558914385460681	0.908814633873343
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	5/5317	17/18639	0.294117647058824	1.03104360043811	0.558914385460681	0.908814633873343
GO:0036041	long-chain fatty acid binding	5/5317	17/18639	0.294117647058824	1.03104360043811	0.558914385460681	0.908814633873343
GO:0045236	CXCR chemokine receptor binding	5/5317	17/18639	0.294117647058824	1.03104360043811	0.558914385460681	0.908814633873343
GO:0070492	oligosaccharide binding	5/5317	17/18639	0.294117647058824	1.03104360043811	0.558914385460681	0.908814633873343
GO:0043015	gamma-tubulin binding	10/5317	35/18639	0.285714285714286	1.00158521185416	0.561423227176443	0.910227439807855
GO:0004864	protein phosphatase inhibitor activity	15/5317	53/18639	0.283018867924528	0.992136294761197	0.566320460538319	0.910227439807855
GO:0005246	calcium channel regulator activity	15/5317	53/18639	0.283018867924528	0.992136294761197	0.566320460538319	0.910227439807855
GO:0020037	heme binding	40/5317	142/18639	0.28169014084507	0.987478377884384	0.5694723795739	0.910227439807855
GO:0016874	ligase activity	47/5317	167/18639	0.281437125748503	0.986591421257541	0.57308643395471	0.910227439807855
GO:0004536	DNA nuclease activity	18/5317	64/18639	0.28125	0.985935442918939	0.575538787237981	0.910227439807855
GO:0001094	TFIID-class transcription factor complex binding	3/5317	10/18639	0.3	1.05166447244687	0.577007350853451	0.910227439807855
GO:0004935	adrenergic receptor activity	3/5317	10/18639	0.3	1.05166447244687	0.577007350853451	0.910227439807855
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	3/5317	10/18639	0.3	1.05166447244687	0.577007350853451	0.910227439807855
GO:0008519	ammonium channel activity	3/5317	10/18639	0.3	1.05166447244687	0.577007350853451	0.910227439807855
GO:0015279	store-operated calcium channel activity	3/5317	10/18639	0.3	1.05166447244687	0.577007350853451	0.910227439807855
GO:0015658	branched-chain amino acid transmembrane transporter activity	3/5317	10/18639	0.3	1.05166447244687	0.577007350853451	0.910227439807855
GO:0019531	oxalate transmembrane transporter activity	3/5317	10/18639	0.3	1.05166447244687	0.577007350853451	0.910227439807855
GO:0031996	thioesterase binding	3/5317	10/18639	0.3	1.05166447244687	0.577007350853451	0.910227439807855
GO:0032356	oxidized DNA binding	3/5317	10/18639	0.3	1.05166447244687	0.577007350853451	0.910227439807855
GO:0035256	G protein-coupled glutamate receptor binding	3/5317	10/18639	0.3	1.05166447244687	0.577007350853451	0.910227439807855
GO:0035374	chondroitin sulfate binding	3/5317	10/18639	0.3	1.05166447244687	0.577007350853451	0.910227439807855
GO:0042975	peroxisome proliferator activated receptor binding	3/5317	10/18639	0.3	1.05166447244687	0.577007350853451	0.910227439807855
GO:0050308	sugar-phosphatase activity	3/5317	10/18639	0.3	1.05166447244687	0.577007350853451	0.910227439807855
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	3/5317	10/18639	0.3	1.05166447244687	0.577007350853451	0.910227439807855
GO:0050815	phosphoserine residue binding	3/5317	10/18639	0.3	1.05166447244687	0.577007350853451	0.910227439807855
GO:0051880	G-quadruplex DNA binding	3/5317	10/18639	0.3	1.05166447244687	0.577007350853451	0.910227439807855
GO:0070739	protein-glutamic acid ligase activity	3/5317	10/18639	0.3	1.05166447244687	0.577007350853451	0.910227439807855
GO:0070740	tubulin-glutamic acid ligase activity	3/5317	10/18639	0.3	1.05166447244687	0.577007350853451	0.910227439807855
GO:0098505	G-rich strand telomeric DNA binding	3/5317	10/18639	0.3	1.05166447244687	0.577007350853451	0.910227439807855
GO:1990757	ubiquitin ligase activator activity	3/5317	10/18639	0.3	1.05166447244687	0.577007350853451	0.910227439807855
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	6/5317	21/18639	0.285714285714286	1.00158521185416	0.580201254546446	0.911310574501542
GO:0070182	DNA polymerase binding	6/5317	21/18639	0.285714285714286	1.00158521185416	0.580201254546446	0.911310574501542
GO:0015932	nucleobase-containing compound transmembrane transporter activity	16/5317	57/18639	0.280701754385965	0.984013541470754	0.580346981578493	0.911310574501542
GO:0070279	vitamin B6 binding	16/5317	57/18639	0.280701754385965	0.984013541470754	0.580346981578493	0.911310574501542
GO:0044183	protein folding chaperone	21/5317	75/18639	0.28	0.981553507617077	0.5837730333348	0.914759247392245
GO:0015605	organophosphate ester transmembrane transporter activity	14/5317	50/18639	0.28	0.981553507617077	0.586098178622481	0.914759247392245
GO:0043177	organic acid binding	53/5317	189/18639	0.28042328042328	0.983037337560565	0.586331628504369	0.914759247392245
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	9/5317	32/18639	0.28125	0.985935442918939	0.586537770707837	0.914759247392245
GO:0042910	xenobiotic transmembrane transporter activity	9/5317	32/18639	0.28125	0.985935442918939	0.586537770707837	0.914759247392245
GO:0140142	nucleocytoplasmic carrier activity	9/5317	32/18639	0.28125	0.985935442918939	0.586537770707837	0.914759247392245
GO:0005245	voltage-gated calcium channel activity	12/5317	43/18639	0.27906976744186	0.978292532508715	0.593155754412048	0.922983522857406
GO:0033293	monocarboxylic acid binding	22/5317	79/18639	0.278481012658228	0.976228624212283	0.595460930961142	0.922983522857406
GO:0008483	transaminase activity	7/5317	25/18639	0.28	0.981553507617077	0.598258730774037	0.922983522857406
GO:0008174	mRNA methyltransferase activity	4/5317	14/18639	0.285714285714286	1.00158521185416	0.598528616350763	0.922983522857406
GO:0015926	glucosidase activity	4/5317	14/18639	0.285714285714286	1.00158521185416	0.598528616350763	0.922983522857406
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	4/5317	14/18639	0.285714285714286	1.00158521185416	0.598528616350763	0.922983522857406
GO:0030983	mismatched DNA binding	4/5317	14/18639	0.285714285714286	1.00158521185416	0.598528616350763	0.922983522857406
GO:0031404	chloride ion binding	4/5317	14/18639	0.285714285714286	1.00158521185416	0.598528616350763	0.922983522857406
GO:0061665	SUMO ligase activity	4/5317	14/18639	0.285714285714286	1.00158521185416	0.598528616350763	0.922983522857406
GO:0098847	sequence-specific single stranded DNA binding	4/5317	14/18639	0.285714285714286	1.00158521185416	0.598528616350763	0.922983522857406
GO:0016409	palmitoyltransferase activity	10/5317	36/18639	0.277777777777778	0.973763400413767	0.602116017472646	0.926436067197554
GO:0055106	ubiquitin-protein transferase regulator activity	10/5317	36/18639	0.277777777777778	0.973763400413767	0.602116017472646	0.926436067197554
GO:0005504	fatty acid binding	13/5317	47/18639	0.276595744680851	0.969619726369453	0.60699879193701	0.932904183581042
GO:0016410	N-acyltransferase activity	26/5317	94/18639	0.276595744680851	0.969619726369453	0.612517352394245	0.934531796959151
GO:0031406	carboxylic acid binding	52/5317	187/18639	0.27807486631016	0.974804858596028	0.613928007097689	0.934531796959151
GO:0043022	ribosome binding	31/5317	112/18639	0.276785714285714	0.970285673983718	0.614246657913262	0.934531796959151
GO:0008308	voltage-gated monoatomic anion channel activity	5/5317	18/18639	0.277777777777778	0.973763400413767	0.616050583689442	0.934531796959151
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	5/5317	18/18639	0.277777777777778	0.973763400413767	0.616050583689442	0.934531796959151
GO:0031690	adrenergic receptor binding	5/5317	18/18639	0.277777777777778	0.973763400413767	0.616050583689442	0.934531796959151
GO:0050811	GABA receptor binding	5/5317	18/18639	0.277777777777778	0.973763400413767	0.616050583689442	0.934531796959151
GO:0070628	proteasome binding	5/5317	18/18639	0.277777777777778	0.973763400413767	0.616050583689442	0.934531796959151
GO:1990381	ubiquitin-specific protease binding	5/5317	18/18639	0.277777777777778	0.973763400413767	0.616050583689442	0.934531796959151
GO:0061791	GTPase motor activity	11/5317	40/18639	0.275	0.96402576640963	0.616219656510183	0.934531796959151
GO:0140662	ATP-dependent protein folding chaperone	11/5317	40/18639	0.275	0.96402576640963	0.616219656510183	0.934531796959151
GO:1990606	membrane scission GTPase motor activity	11/5317	40/18639	0.275	0.96402576640963	0.616219656510183	0.934531796959151
GO:0008080	N-acetyltransferase activity	19/5317	69/18639	0.27536231884058	0.965295892584082	0.617271572874215	0.935094973681555
GO:0016597	amino acid binding	14/5317	51/18639	0.274509803921569	0.962307360408899	0.619785851984192	0.937869780425418
GO:0004521	RNA endonuclease activity	20/5317	73/18639	0.273972602739726	0.960424175750565	0.628181402155571	0.949528324050335
GO:0019205	nucleobase-containing compound kinase activity	12/5317	44/18639	0.272727272727273	0.956058611315335	0.629124749881329	0.94974201040016
GO:0008970	phospholipase A1 activity	6/5317	22/18639	0.272727272727273	0.956058611315335	0.631087667754982	0.94974201040016
GO:0016881	acid-amino acid ligase activity	6/5317	22/18639	0.272727272727273	0.956058611315335	0.631087667754982	0.94974201040016
GO:0033691	sialic acid binding	6/5317	22/18639	0.272727272727273	0.956058611315335	0.631087667754982	0.94974201040016
GO:0030551	cyclic nucleotide binding	10/5317	37/18639	0.27027027027027	0.947445470672855	0.640894805107495	0.960715769640893
GO:0005227	calcium-activated cation channel activity	7/5317	26/18639	0.269230769230769	0.943801449631805	0.644390429387715	0.960715769640893
GO:0008066	glutamate receptor activity	7/5317	26/18639	0.269230769230769	0.943801449631805	0.644390429387715	0.960715769640893
GO:0015216	purine nucleotide transmembrane transporter activity	7/5317	26/18639	0.269230769230769	0.943801449631805	0.644390429387715	0.960715769640893
GO:0030507	spectrin binding	7/5317	26/18639	0.269230769230769	0.943801449631805	0.644390429387715	0.960715769640893
GO:0050681	nuclear androgen receptor binding	7/5317	26/18639	0.269230769230769	0.943801449631805	0.644390429387715	0.960715769640893
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	3/5317	11/18639	0.272727272727273	0.956058611315335	0.648168499604882	0.960715769640893
GO:0008271	secondary active sulfate transmembrane transporter activity	3/5317	11/18639	0.272727272727273	0.956058611315335	0.648168499604882	0.960715769640893
GO:0008432	JUN kinase binding	3/5317	11/18639	0.272727272727273	0.956058611315335	0.648168499604882	0.960715769640893
GO:0008526	phosphatidylinositol transfer activity	3/5317	11/18639	0.272727272727273	0.956058611315335	0.648168499604882	0.960715769640893
GO:0015173	aromatic amino acid transmembrane transporter activity	3/5317	11/18639	0.272727272727273	0.956058611315335	0.648168499604882	0.960715769640893
GO:0019206	nucleoside kinase activity	3/5317	11/18639	0.272727272727273	0.956058611315335	0.648168499604882	0.960715769640893
GO:0099528	G protein-coupled neurotransmitter receptor activity	3/5317	11/18639	0.272727272727273	0.956058611315335	0.648168499604882	0.960715769640893
GO:0140537	transcription regulator activator activity	3/5317	11/18639	0.272727272727273	0.956058611315335	0.648168499604882	0.960715769640893
GO:0015175	neutral L-amino acid transmembrane transporter activity	11/5317	41/18639	0.268292682926829	0.940512942838663	0.652589756871238	0.9635381453849
GO:1901682	sulfur compound transmembrane transporter activity	17/5317	63/18639	0.26984126984127	0.945941588973374	0.653212408789227	0.9635381453849
GO:0016769	transferase activity, transferring nitrogenous groups	8/5317	30/18639	0.266666666666667	0.934812864397216	0.656392976402615	0.9635381453849
GO:0000774	adenyl-nucleotide exchange factor activity	4/5317	15/18639	0.266666666666667	0.934812864397216	0.658487859182257	0.9635381453849
GO:0005402	carbohydrate:monoatomic cation symporter activity	4/5317	15/18639	0.266666666666667	0.934812864397216	0.658487859182257	0.9635381453849
GO:0015116	sulfate transmembrane transporter activity	4/5317	15/18639	0.266666666666667	0.934812864397216	0.658487859182257	0.9635381453849
GO:0015929	hexosaminidase activity	4/5317	15/18639	0.266666666666667	0.934812864397216	0.658487859182257	0.9635381453849
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	4/5317	15/18639	0.266666666666667	0.934812864397216	0.658487859182257	0.9635381453849
GO:0017081	chloride channel regulator activity	4/5317	15/18639	0.266666666666667	0.934812864397216	0.658487859182257	0.9635381453849
GO:0031005	filamin binding	4/5317	15/18639	0.266666666666667	0.934812864397216	0.658487859182257	0.9635381453849
GO:0033130	acetylcholine receptor binding	4/5317	15/18639	0.266666666666667	0.934812864397216	0.658487859182257	0.9635381453849
GO:0048531	beta-1,3-galactosyltransferase activity	4/5317	15/18639	0.266666666666667	0.934812864397216	0.658487859182257	0.9635381453849
GO:0016407	acetyltransferase activity	26/5317	96/18639	0.270833333333333	0.949419315403423	0.660420151669178	0.965337540844097
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	9/5317	34/18639	0.264705882352941	0.927939240394296	0.667372551309475	0.970005246599079
GO:0051427	hormone receptor binding	9/5317	34/18639	0.264705882352941	0.927939240394296	0.667372551309475	0.970005246599079
GO:0005346	purine ribonucleotide transmembrane transporter activity	5/5317	19/18639	0.263157894736842	0.922512695128832	0.668555290050457	0.970005246599079
GO:0008381	mechanosensitive monoatomic ion channel activity	5/5317	19/18639	0.263157894736842	0.922512695128832	0.668555290050457	0.970005246599079
GO:0008574	plus-end-directed microtubule motor activity	5/5317	19/18639	0.263157894736842	0.922512695128832	0.668555290050457	0.970005246599079
GO:0022840	leak channel activity	5/5317	19/18639	0.263157894736842	0.922512695128832	0.668555290050457	0.970005246599079
GO:0022842	narrow pore channel activity	5/5317	19/18639	0.263157894736842	0.922512695128832	0.668555290050457	0.970005246599079
GO:0004175	endopeptidase activity	112/5317	405/18639	0.276543209876543	0.969435563078595	0.670875220194909	0.972344464712874
GO:0000295	adenine nucleotide transmembrane transporter activity	6/5317	23/18639	0.260869565217391	0.914490845605973	0.678154332035135	0.976712842993999
GO:0004602	glutathione peroxidase activity	6/5317	23/18639	0.260869565217391	0.914490845605973	0.678154332035135	0.976712842993999
GO:0005212	structural constituent of eye lens	6/5317	23/18639	0.260869565217391	0.914490845605973	0.678154332035135	0.976712842993999
GO:0017134	fibroblast growth factor binding	6/5317	23/18639	0.260869565217391	0.914490845605973	0.678154332035135	0.976712842993999
GO:0042171	lysophosphatidic acid acyltransferase activity	6/5317	23/18639	0.260869565217391	0.914490845605973	0.678154332035135	0.976712842993999
GO:0071617	lysophospholipid acyltransferase activity	6/5317	23/18639	0.260869565217391	0.914490845605973	0.678154332035135	0.976712842993999
GO:0016209	antioxidant activity	23/5317	86/18639	0.267441860465116	0.937530343654185	0.681896796298124	0.981074552998558
GO:0001671	ATPase activator activity	7/5317	27/18639	0.259259259259259	0.908845840386183	0.687252782724368	0.986714026607399
GO:0004364	glutathione transferase activity	7/5317	27/18639	0.259259259259259	0.908845840386183	0.687252782724368	0.986714026607399
GO:0016798	hydrolase activity, acting on glycosyl bonds	35/5317	130/18639	0.269230769230769	0.943801449631805	0.689018557509784	0.987284602591167
GO:0061630	ubiquitin protein ligase activity	97/5317	353/18639	0.274787535410765	0.963280961542458	0.689087288125858	0.987284602591167
GO:0004601	peroxidase activity	15/5317	57/18639	0.263157894736842	0.922512695128832	0.691760039756174	0.990081556901023
GO:0072349	modified amino acid transmembrane transporter activity	8/5317	31/18639	0.258064516129032	0.904657610706984	0.695871822060623	0.992840645681604
GO:0061659	ubiquitin-like protein ligase activity	102/5317	372/18639	0.274193548387097	0.96119871137617	0.701867567402395	0.992840645681604
GO:0016229	steroid dehydrogenase activity	9/5317	35/18639	0.257142857142857	0.901426690668744	0.704047317355524	0.992840645681604
GO:0016829	lyase activity	54/5317	200/18639	0.27	0.946498025202182	0.709363696408969	0.992840645681604
GO:0004300	enoyl-CoA hydratase activity	3/5317	12/18639	0.25	0.87638706037239	0.710331998276189	0.992840645681604
GO:0004859	phospholipase inhibitor activity	3/5317	12/18639	0.25	0.87638706037239	0.710331998276189	0.992840645681604
GO:0005049	nuclear export signal receptor activity	3/5317	12/18639	0.25	0.87638706037239	0.710331998276189	0.992840645681604
GO:0005165	neurotrophin receptor binding	3/5317	12/18639	0.25	0.87638706037239	0.710331998276189	0.992840645681604
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	3/5317	12/18639	0.25	0.87638706037239	0.710331998276189	0.992840645681604
GO:0015269	calcium-activated potassium channel activity	3/5317	12/18639	0.25	0.87638706037239	0.710331998276189	0.992840645681604
GO:0016423	tRNA (guanine) methyltransferase activity	3/5317	12/18639	0.25	0.87638706037239	0.710331998276189	0.992840645681604
GO:0035251	UDP-glucosyltransferase activity	3/5317	12/18639	0.25	0.87638706037239	0.710331998276189	0.992840645681604
GO:0036009	protein-glutamine N-methyltransferase activity	3/5317	12/18639	0.25	0.87638706037239	0.710331998276189	0.992840645681604
GO:0042301	phosphate ion binding	3/5317	12/18639	0.25	0.87638706037239	0.710331998276189	0.992840645681604
GO:0070008	serine-type exopeptidase activity	3/5317	12/18639	0.25	0.87638706037239	0.710331998276189	0.992840645681604
GO:0070410	co-SMAD binding	3/5317	12/18639	0.25	0.87638706037239	0.710331998276189	0.992840645681604
GO:0097371	MDM2/MDM4 family protein binding	3/5317	12/18639	0.25	0.87638706037239	0.710331998276189	0.992840645681604
GO:0097677	STAT family protein binding	3/5317	12/18639	0.25	0.87638706037239	0.710331998276189	0.992840645681604
GO:0140829	bicarbonate:monoatomic anion antiporter activity	3/5317	12/18639	0.25	0.87638706037239	0.710331998276189	0.992840645681604
GO:0140900	chloride:bicarbonate antiporter activity	3/5317	12/18639	0.25	0.87638706037239	0.710331998276189	0.992840645681604
GO:0003688	DNA replication origin binding	4/5317	16/18639	0.25	0.87638706037239	0.712055666939051	0.992840645681604
GO:0016675	oxidoreductase activity, acting on a heme group of donors	4/5317	16/18639	0.25	0.87638706037239	0.712055666939051	0.992840645681604
GO:0019841	retinol binding	4/5317	16/18639	0.25	0.87638706037239	0.712055666939051	0.992840645681604
GO:0022858	alanine transmembrane transporter activity	4/5317	16/18639	0.25	0.87638706037239	0.712055666939051	0.992840645681604
GO:0015297	antiporter activity	36/5317	135/18639	0.266666666666667	0.934812864397216	0.71448900859711	0.992840645681604
GO:0000339	RNA cap binding	5/5317	20/18639	0.25	0.87638706037239	0.71608812217647	0.992840645681604
GO:0001614	purinergic nucleotide receptor activity	5/5317	20/18639	0.25	0.87638706037239	0.71608812217647	0.992840645681604
GO:0015095	magnesium ion transmembrane transporter activity	5/5317	20/18639	0.25	0.87638706037239	0.71608812217647	0.992840645681604
GO:0016502	nucleotide receptor activity	5/5317	20/18639	0.25	0.87638706037239	0.71608812217647	0.992840645681604
GO:0042288	MHC class I protein binding	5/5317	20/18639	0.25	0.87638706037239	0.71608812217647	0.992840645681604
GO:0043024	ribosomal small subunit binding	5/5317	20/18639	0.25	0.87638706037239	0.71608812217647	0.992840645681604
GO:0004806	triacylglycerol lipase activity	6/5317	24/18639	0.25	0.87638706037239	0.721137385053121	0.996823709318902
GO:0005540	hyaluronic acid binding	6/5317	24/18639	0.25	0.87638706037239	0.721137385053121	0.996823709318902
GO:0015295	solute:proton symporter activity	6/5317	24/18639	0.25	0.87638706037239	0.721137385053121	0.996823709318902
GO:0019842	vitamin binding	40/5317	150/18639	0.266666666666667	0.934812864397216	0.721966311978712	0.996966545385679
GO:0016651	oxidoreductase activity, acting on NAD(P)H	23/5317	88/18639	0.261363636363636	0.916222835843863	0.727436780172859	1
GO:0031369	translation initiation factor binding	8/5317	32/18639	0.25	0.87638706037239	0.732316505844885	1
GO:0005253	monoatomic anion channel activity	27/5317	103/18639	0.262135922330097	0.918930121555516	0.732668107197594	1
GO:0140313	molecular sequestering activity	14/5317	55/18639	0.254545454545455	0.892321370560979	0.739497080238256	1
GO:0031593	polyubiquitin modification-dependent protein binding	15/5317	59/18639	0.254237288135593	0.891241078344804	0.745701634958316	1
GO:0036002	pre-mRNA binding	15/5317	59/18639	0.254237288135593	0.891241078344804	0.745701634958316	1
GO:0005507	copper ion binding	16/5317	63/18639	0.253968253968254	0.890297966092587	0.751663155926103	1
GO:0019200	carbohydrate kinase activity	5/5317	21/18639	0.238095238095238	0.8346543432118	0.758552768310852	1
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	5/5317	21/18639	0.238095238095238	0.8346543432118	0.758552768310852	1
GO:0004029	aldehyde dehydrogenase (NAD+) activity	4/5317	17/18639	0.235294117647059	0.824834880350485	0.759176061240088	1
GO:0004550	nucleoside diphosphate kinase activity	4/5317	17/18639	0.235294117647059	0.824834880350485	0.759176061240088	1
GO:0004659	prenyltransferase activity	4/5317	17/18639	0.235294117647059	0.824834880350485	0.759176061240088	1
GO:0070402	NADPH binding	4/5317	17/18639	0.235294117647059	0.824834880350485	0.759176061240088	1
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	6/5317	25/18639	0.24	0.841331577957495	0.759941170614937	1
GO:0051087	protein-folding chaperone binding	35/5317	134/18639	0.261194029850746	0.915628272030856	0.760648922963767	1
GO:0106222	lncRNA binding	7/5317	29/18639	0.241379310344828	0.846166816911274	0.762464679438063	1
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	3/5317	13/18639	0.230769230769231	0.808972671112976	0.763647035017121	1
GO:0004465	lipoprotein lipase activity	3/5317	13/18639	0.230769230769231	0.808972671112976	0.763647035017121	1
GO:0005542	folic acid binding	3/5317	13/18639	0.230769230769231	0.808972671112976	0.763647035017121	1
GO:0008253	5'-nucleotidase activity	3/5317	13/18639	0.230769230769231	0.808972671112976	0.763647035017121	1
GO:0032396	inhibitory MHC class I receptor activity	3/5317	13/18639	0.230769230769231	0.808972671112976	0.763647035017121	1
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	3/5317	13/18639	0.230769230769231	0.808972671112976	0.763647035017121	1
GO:0051011	microtubule minus-end binding	3/5317	13/18639	0.230769230769231	0.808972671112976	0.763647035017121	1
GO:1901338	catecholamine binding	3/5317	13/18639	0.230769230769231	0.808972671112976	0.763647035017121	1
GO:0008509	monoatomic anion transmembrane transporter activity	39/5317	149/18639	0.261744966442953	0.917559606832838	0.765212560210153	1
GO:0140311	protein sequestering activity	8/5317	33/18639	0.242424242424242	0.849829876724742	0.765655625442498	1
GO:0005254	chloride channel activity	21/5317	83/18639	0.253012048192771	0.886945940617841	0.778369877397702	1
GO:0016763	pentosyltransferase activity	12/5317	49/18639	0.244897959183673	0.858501610160709	0.781036681262869	1
GO:0060590	ATPase regulator activity	12/5317	49/18639	0.244897959183673	0.858501610160709	0.781036681262869	1
GO:0015108	chloride transmembrane transporter activity	31/5317	121/18639	0.256198347107438	0.898115665175012	0.789964908039575	1
GO:0001637	G protein-coupled chemoattractant receptor activity	6/5317	26/18639	0.230769230769231	0.808972671112976	0.794606392983103	1
GO:0004529	DNA exonuclease activity	6/5317	26/18639	0.230769230769231	0.808972671112976	0.794606392983103	1
GO:0004950	chemokine receptor activity	6/5317	26/18639	0.230769230769231	0.808972671112976	0.794606392983103	1
GO:0031210	phosphatidylcholine binding	7/5317	30/18639	0.233333333333333	0.817961256347564	0.794747371666243	1
GO:0033612	receptor serine/threonine kinase binding	7/5317	30/18639	0.233333333333333	0.817961256347564	0.794747371666243	1
GO:0015377	chloride:monoatomic cation symporter activity	5/5317	22/18639	0.227272727272727	0.796715509429446	0.796042503768461	1
GO:0043021	ribonucleoprotein complex binding	46/5317	177/18639	0.259887005649718	0.911046435641355	0.797077574611077	1
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	4/5317	18/18639	0.222222222222222	0.779010720331014	0.800069054825987	1
GO:0004970	glutamate-gated receptor activity	4/5317	18/18639	0.222222222222222	0.779010720331014	0.800069054825987	1
GO:0099602	neurotransmitter receptor regulator activity	4/5317	18/18639	0.222222222222222	0.779010720331014	0.800069054825987	1
GO:1901611	phosphatidylglycerol binding	4/5317	18/18639	0.222222222222222	0.779010720331014	0.800069054825987	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	47/5317	181/18639	0.259668508287293	0.910280482596737	0.801142360230484	1
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	11/5317	46/18639	0.239130434782609	0.838283275138808	0.802540258935475	1
GO:0005347	ATP transmembrane transporter activity	3/5317	14/18639	0.214285714285714	0.75118890889062	0.808679331017037	1
GO:0008392	arachidonate epoxygenase activity	3/5317	14/18639	0.214285714285714	0.75118890889062	0.808679331017037	1
GO:0008494	translation activator activity	3/5317	14/18639	0.214285714285714	0.75118890889062	0.808679331017037	1
GO:0015386	potassium:proton antiporter activity	3/5317	14/18639	0.214285714285714	0.75118890889062	0.808679331017037	1
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	3/5317	14/18639	0.214285714285714	0.75118890889062	0.808679331017037	1
GO:0034236	protein kinase A catalytic subunit binding	3/5317	14/18639	0.214285714285714	0.75118890889062	0.808679331017037	1
GO:0043176	amine binding	3/5317	14/18639	0.214285714285714	0.75118890889062	0.808679331017037	1
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	3/5317	14/18639	0.214285714285714	0.75118890889062	0.808679331017037	1
GO:1901612	cardiolipin binding	3/5317	14/18639	0.214285714285714	0.75118890889062	0.808679331017037	1
GO:0015081	sodium ion transmembrane transporter activity	42/5317	164/18639	0.25609756097561	0.897762354527815	0.820107520489835	1
GO:0048029	monosaccharide binding	18/5317	74/18639	0.243243243243243	0.852700923605569	0.823490794107502	1
GO:0005452	solute:inorganic anion antiporter activity	7/5317	31/18639	0.225806451612903	0.791575409368611	0.823586073634549	1
GO:0008327	methyl-CpG binding	7/5317	31/18639	0.225806451612903	0.791575409368611	0.823586073634549	1
GO:0047499	calcium-independent phospholipase A2 activity	7/5317	31/18639	0.225806451612903	0.791575409368611	0.823586073634549	1
GO:0005200	structural constituent of cytoskeleton	28/5317	112/18639	0.25	0.87638706037239	0.824357948812245	1
GO:0005104	fibroblast growth factor receptor binding	6/5317	27/18639	0.222222222222222	0.779010720331014	0.825278853057027	1
GO:0008395	steroid hydroxylase activity	6/5317	27/18639	0.222222222222222	0.779010720331014	0.825278853057027	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	6/5317	27/18639	0.222222222222222	0.779010720331014	0.825278853057027	1
GO:0000182	rDNA binding	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:0003680	minor groove of adenine-thymine-rich DNA binding	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:0005345	purine nucleobase transmembrane transporter activity	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:0005381	iron ion transmembrane transporter activity	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:0008239	dipeptidyl-peptidase activity	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:0008401	retinoic acid 4-hydroxylase activity	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:0008641	ubiquitin-like modifier activating enzyme activity	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:0015187	glycine transmembrane transporter activity	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:0015203	polyamine transmembrane transporter activity	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:0019911	structural constituent of myelin sheath	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:0043208	glycosphingolipid binding	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:0043295	glutathione binding	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:0045322	unmethylated CpG binding	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:0051378	serotonin binding	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:0070097	delta-catenin binding	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:0140135	mechanosensitive monoatomic cation channel activity	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:0140940	histone H2A methyltransferase activity	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:0140999	histone H3K4 trimethyltransferase activity	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:1990259	histone H2AQ104 methyltransferase activity	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:1990763	arrestin family protein binding	2/5317	10/18639	0.2	0.701109648297912	0.826426173071777	1
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	5/5317	23/18639	0.217391304347826	0.762075704671644	0.828789218138829	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	5/5317	23/18639	0.217391304347826	0.762075704671644	0.828789218138829	1
GO:0016493	C-C chemokine receptor activity	5/5317	23/18639	0.217391304347826	0.762075704671644	0.828789218138829	1
GO:0016917	GABA receptor activity	5/5317	23/18639	0.217391304347826	0.762075704671644	0.828789218138829	1
GO:0099186	structural constituent of postsynapse	5/5317	23/18639	0.217391304347826	0.762075704671644	0.828789218138829	1
GO:0140103	catalytic activity, acting on a glycoprotein	5/5317	23/18639	0.217391304347826	0.762075704671644	0.828789218138829	1
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	5/5317	23/18639	0.217391304347826	0.762075704671644	0.828789218138829	1
GO:0005267	potassium channel activity	31/5317	124/18639	0.25	0.87638706037239	0.834401355600826	1
GO:0005229	intracellularly calcium-gated chloride channel activity	4/5317	19/18639	0.210526315789474	0.738010156103066	0.835139392099461	1
GO:0031420	alkali metal ion binding	4/5317	19/18639	0.210526315789474	0.738010156103066	0.835139392099461	1
GO:0042834	peptidoglycan binding	4/5317	19/18639	0.210526315789474	0.738010156103066	0.835139392099461	1
GO:0046527	glucosyltransferase activity	4/5317	19/18639	0.210526315789474	0.738010156103066	0.835139392099461	1
GO:0141147	intracellularly calcium-gated channel activity	4/5317	19/18639	0.210526315789474	0.738010156103066	0.835139392099461	1
GO:0008173	RNA methyltransferase activity	16/5317	67/18639	0.238805970149254	0.837145848713925	0.83614465910567	1
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	59/5317	229/18639	0.25764192139738	0.903176184488577	0.842618594933482	1
GO:0099094	ligand-gated monoatomic cation channel activity	34/5317	136/18639	0.25	0.87638706037239	0.843722499869332	1
GO:0004089	carbonate dehydratase activity	3/5317	15/18639	0.2	0.701109648297912	0.846227198975731	1
GO:0004129	cytochrome-c oxidase activity	3/5317	15/18639	0.2	0.701109648297912	0.846227198975731	1
GO:0008020	G protein-coupled photoreceptor activity	3/5317	15/18639	0.2	0.701109648297912	0.846227198975731	1
GO:0008242	omega peptidase activity	3/5317	15/18639	0.2	0.701109648297912	0.846227198975731	1
GO:0008252	nucleotidase activity	3/5317	15/18639	0.2	0.701109648297912	0.846227198975731	1
GO:0015250	water channel activity	3/5317	15/18639	0.2	0.701109648297912	0.846227198975731	1
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	3/5317	15/18639	0.2	0.701109648297912	0.846227198975731	1
GO:0030553	cGMP binding	3/5317	15/18639	0.2	0.701109648297912	0.846227198975731	1
GO:0045504	dynein heavy chain binding	3/5317	15/18639	0.2	0.701109648297912	0.846227198975731	1
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	9/5317	40/18639	0.225	0.788748354335152	0.846646277732903	1
GO:0038187	pattern recognition receptor activity	11/5317	48/18639	0.229166666666667	0.803354805341358	0.846995118626558	1
GO:0030515	snoRNA binding	7/5317	32/18639	0.21875	0.766838677825842	0.849141552615655	1
GO:0047498	calcium-dependent phospholipase A2 activity	7/5317	32/18639	0.21875	0.766838677825842	0.849141552615655	1
GO:0051059	NF-kappaB binding	7/5317	32/18639	0.21875	0.766838677825842	0.849141552615655	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	22/5317	91/18639	0.241758241758242	0.847495179261213	0.850707263199509	1
GO:0019789	SUMO transferase activity	6/5317	28/18639	0.214285714285714	0.75118890889062	0.852180628473103	1
GO:0030145	manganese ion binding	16/5317	68/18639	0.235294117647059	0.824834880350485	0.853458303219781	1
GO:0000049	tRNA binding	19/5317	80/18639	0.2375	0.832567707353771	0.858945004514066	1
GO:0015079	potassium ion transmembrane transporter activity	40/5317	160/18639	0.25	0.87638706037239	0.860475369919613	1
GO:0180051	translation factor activity	20/5317	84/18639	0.238095238095238	0.8346543432118	0.860880025005952	1
GO:0008194	UDP-glycosyltransferase activity	36/5317	145/18639	0.248275862068966	0.870343011680167	0.861085955392423	1
GO:0005216	monoatomic ion channel activity	118/5317	448/18639	0.263392857142857	0.923336367178054	0.862615298939722	1
GO:0052689	carboxylic ester hydrolase activity	22/5317	92/18639	0.239130434782609	0.838283275138808	0.864826477224944	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	4/5317	20/18639	0.2	0.701109648297912	0.864902209580209	1
GO:0015464	acetylcholine receptor activity	4/5317	20/18639	0.2	0.701109648297912	0.864902209580209	1
GO:0016408	C-acyltransferase activity	4/5317	20/18639	0.2	0.701109648297912	0.864902209580209	1
GO:0015291	secondary active transmembrane transporter activity	74/5317	287/18639	0.257839721254355	0.903869581429364	0.865412203571136	1
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	2/5317	11/18639	0.181818181818182	0.637372407543557	0.866038989397754	1
GO:0005221	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	2/5317	11/18639	0.181818181818182	0.637372407543557	0.866038989397754	1
GO:0008199	ferric iron binding	2/5317	11/18639	0.181818181818182	0.637372407543557	0.866038989397754	1
GO:0015205	nucleobase transmembrane transporter activity	2/5317	11/18639	0.181818181818182	0.637372407543557	0.866038989397754	1
GO:0015217	ADP transmembrane transporter activity	2/5317	11/18639	0.181818181818182	0.637372407543557	0.866038989397754	1
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/5317	11/18639	0.181818181818182	0.637372407543557	0.866038989397754	1
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	2/5317	11/18639	0.181818181818182	0.637372407543557	0.866038989397754	1
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	2/5317	11/18639	0.181818181818182	0.637372407543557	0.866038989397754	1
GO:0043855	cyclic nucleotide-activated monoatomic ion channel activity	2/5317	11/18639	0.181818181818182	0.637372407543557	0.866038989397754	1
GO:0070697	activin receptor binding	2/5317	11/18639	0.181818181818182	0.637372407543557	0.866038989397754	1
GO:0070990	snRNP binding	2/5317	11/18639	0.181818181818182	0.637372407543557	0.866038989397754	1
GO:1900750	oligopeptide binding	2/5317	11/18639	0.181818181818182	0.637372407543557	0.866038989397754	1
GO:1901505	carbohydrate derivative transmembrane transporter activity	12/5317	53/18639	0.226415094339623	0.793709035808957	0.866182154145739	1
GO:0042287	MHC protein binding	9/5317	41/18639	0.219512195121951	0.76951058959527	0.867340224402872	1
GO:0140098	catalytic activity, acting on RNA	101/5317	387/18639	0.260981912144703	0.914884683179446	0.870373901362788	1
GO:0046982	protein heterodimerization activity	96/5317	369/18639	0.260162601626016	0.912012550631431	0.872713669448621	1
GO:0005416	amino acid:monoatomic cation symporter activity	6/5317	29/18639	0.206896551724138	0.725285843066806	0.875584789090939	1
GO:0051861	glycolipid binding	6/5317	29/18639	0.206896551724138	0.725285843066806	0.875584789090939	1
GO:0005506	iron ion binding	38/5317	154/18639	0.246753246753247	0.865005410237684	0.876388545899834	1
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	3/5317	16/18639	0.1875	0.657290295279293	0.877189860214965	1
GO:0008391	arachidonate monooxygenase activity	3/5317	16/18639	0.1875	0.657290295279293	0.877189860214965	1
GO:0015378	sodium:chloride symporter activity	3/5317	16/18639	0.1875	0.657290295279293	0.877189860214965	1
GO:0022843	voltage-gated monoatomic cation channel activity	35/5317	143/18639	0.244755244755245	0.858001317847096	0.880090520656046	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	5/5317	25/18639	0.2	0.701109648297912	0.881413017219049	1
GO:0047617	fatty acyl-CoA hydrolase activity	5/5317	25/18639	0.2	0.701109648297912	0.881413017219049	1
GO:0005261	monoatomic cation channel activity	88/5317	341/18639	0.258064516129032	0.904657610706984	0.882341903291649	1
GO:0017069	snRNA binding	12/5317	54/18639	0.222222222222222	0.779010720331014	0.882742435643316	1
GO:0050661	NADP binding	12/5317	54/18639	0.222222222222222	0.779010720331014	0.882742435643316	1
GO:0031491	nucleosome binding	17/5317	74/18639	0.22972972972973	0.805328650071926	0.884592035554559	1
GO:0042887	amide transmembrane transporter activity	8/5317	38/18639	0.210526315789474	0.738010156103066	0.887994795701636	1
GO:0015174	basic amino acid transmembrane transporter activity	4/5317	21/18639	0.19047619047619	0.66772347456944	0.88992560752594	1
GO:0051428	peptide hormone receptor binding	4/5317	21/18639	0.19047619047619	0.66772347456944	0.88992560752594	1
GO:0016758	hexosyltransferase activity	49/5317	197/18639	0.248730964467005	0.871938395091312	0.890096233349249	1
GO:0016831	carboxy-lyase activity	7/5317	34/18639	0.205882352941176	0.721730520306674	0.891250152702943	1
GO:0015171	amino acid transmembrane transporter activity	24/5317	102/18639	0.235294117647059	0.824834880350485	0.892525860229466	1
GO:0004497	monooxygenase activity	25/5317	106/18639	0.235849056603774	0.826780245634331	0.893853904055749	1
GO:0098918	structural constituent of synapse	6/5317	30/18639	0.2	0.701109648297912	0.895794143447114	1
GO:0008504	monoamine transmembrane transporter activity	2/5317	12/18639	0.166666666666667	0.58425804024826	0.897180387622067	1
GO:0015132	prostaglandin transmembrane transporter activity	2/5317	12/18639	0.166666666666667	0.58425804024826	0.897180387622067	1
GO:0031543	peptidyl-proline dioxygenase activity	2/5317	12/18639	0.166666666666667	0.58425804024826	0.897180387622067	1
GO:0003743	translation initiation factor activity	11/5317	51/18639	0.215686274509804	0.756098640321278	0.898541554051734	1
GO:0008135	translation factor activity, RNA binding	19/5317	83/18639	0.228915662650602	0.802474898654237	0.898569416153842	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	9/5317	43/18639	0.209302325581395	0.733719399381536	0.901930675342265	1
GO:0016289	acyl-CoA hydrolase activity	5/5317	26/18639	0.192307692307692	0.674143892594147	0.90208126108475	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	3/5317	17/18639	0.176470588235294	0.618626160262864	0.902478531423868	1
GO:0016018	cyclosporin A binding	3/5317	17/18639	0.176470588235294	0.618626160262864	0.902478531423868	1
GO:0030548	acetylcholine receptor regulator activity	3/5317	17/18639	0.176470588235294	0.618626160262864	0.902478531423868	1
GO:0015103	inorganic anion transmembrane transporter activity	40/5317	165/18639	0.242424242424242	0.849829876724742	0.906679233511406	1
GO:0016757	glycosyltransferase activity	67/5317	267/18639	0.250936329588015	0.879669408913111	0.907776557314416	1
GO:0004623	phospholipase A2 activity	7/5317	35/18639	0.2	0.701109648297912	0.908284899603761	1
GO:0051536	iron-sulfur cluster binding	17/5317	76/18639	0.223684210526316	0.784135790859507	0.909010692288596	1
GO:0005243	gap junction channel activity	4/5317	22/18639	0.181818181818182	0.637372407543557	0.910788519472046	1
GO:0016411	acylglycerol O-acyltransferase activity	6/5317	31/18639	0.193548387096774	0.678493208030238	0.913124080202129	1
GO:0001653	peptide receptor activity	30/5317	128/18639	0.234375	0.821612869099116	0.918043888432593	1
GO:0050997	quaternary ammonium group binding	8/5317	40/18639	0.2	0.701109648297912	0.91914330431319	1
GO:0051540	metal cluster binding	17/5317	77/18639	0.220779220779221	0.773952209160033	0.919529134248999	1
GO:0004993	G protein-coupled serotonin receptor activity	2/5317	13/18639	0.153846153846154	0.539315114075317	0.921459179004784	1
GO:0015651	quaternary ammonium group transmembrane transporter activity	2/5317	13/18639	0.153846153846154	0.539315114075317	0.921459179004784	1
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	2/5317	13/18639	0.153846153846154	0.539315114075317	0.921459179004784	1
GO:0019104	DNA N-glycosylase activity	2/5317	13/18639	0.153846153846154	0.539315114075317	0.921459179004784	1
GO:0030955	potassium ion binding	2/5317	13/18639	0.153846153846154	0.539315114075317	0.921459179004784	1
GO:0031432	titin binding	2/5317	13/18639	0.153846153846154	0.539315114075317	0.921459179004784	1
GO:0035673	oligopeptide transmembrane transporter activity	2/5317	13/18639	0.153846153846154	0.539315114075317	0.921459179004784	1
GO:0071714	icosanoid transmembrane transporter activity	2/5317	13/18639	0.153846153846154	0.539315114075317	0.921459179004784	1
GO:0140410	monoatomic cation:bicarbonate symporter activity	2/5317	13/18639	0.153846153846154	0.539315114075317	0.921459179004784	1
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	13/5317	61/18639	0.213114754098361	0.747084051464989	0.921527094102161	1
GO:0016836	hydro-lyase activity	13/5317	61/18639	0.213114754098361	0.747084051464989	0.921527094102161	1
GO:0005372	water transmembrane transporter activity	3/5317	18/18639	0.166666666666667	0.58425804024826	0.922960426743444	1
GO:0015373	monoatomic anion:sodium symporter activity	3/5317	18/18639	0.166666666666667	0.58425804024826	0.922960426743444	1
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	3/5317	18/18639	0.166666666666667	0.58425804024826	0.922960426743444	1
GO:0022851	GABA-gated chloride ion channel activity	3/5317	18/18639	0.166666666666667	0.58425804024826	0.922960426743444	1
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	3/5317	18/18639	0.166666666666667	0.58425804024826	0.922960426743444	1
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	7/5317	36/18639	0.194444444444444	0.681634380289637	0.922976025326596	1
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	7/5317	36/18639	0.194444444444444	0.681634380289637	0.922976025326596	1
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	7/5317	36/18639	0.194444444444444	0.681634380289637	0.922976025326596	1
GO:0008236	serine-type peptidase activity	47/5317	194/18639	0.242268041237113	0.849282305927884	0.923016906570265	1
GO:0022832	voltage-gated channel activity	42/5317	175/18639	0.24	0.841331577957495	0.923625202569242	1
GO:0016251	RNA polymerase II general transcription initiation factor activity	11/5317	53/18639	0.207547169811321	0.727566616158211	0.92418995510955	1
GO:0017171	serine hydrolase activity	48/5317	198/18639	0.242424242424242	0.849829876724742	0.924203509629938	1
GO:0051082	unfolded protein binding	28/5317	121/18639	0.231404958677686	0.811201245964527	0.924219209085786	1
GO:0008378	galactosyltransferase activity	6/5317	32/18639	0.1875	0.657290295279293	0.927889278875931	1
GO:0005283	amino acid:sodium symporter activity	4/5317	23/18639	0.173913043478261	0.609660563737315	0.928051530279039	1
GO:0005249	voltage-gated potassium channel activity	22/5317	98/18639	0.224489795918367	0.786959809313983	0.929041252647387	1
GO:0042626	ATPase-coupled transmembrane transporter activity	22/5317	98/18639	0.224489795918367	0.786959809313983	0.929041252647387	1
GO:0004252	serine-type endopeptidase activity	42/5317	176/18639	0.238636363636364	0.836551284900918	0.929948071805894	1
GO:0008528	G protein-coupled peptide receptor activity	28/5317	122/18639	0.229508196721311	0.804552055423834	0.931633215438957	1
GO:0008137	NADH dehydrogenase (ubiquinone) activity	8/5317	41/18639	0.195121951219512	0.684009412973573	0.931701626715691	1
GO:0008227	G protein-coupled amine receptor activity	8/5317	41/18639	0.195121951219512	0.684009412973573	0.931701626715691	1
GO:0005242	inward rectifier potassium channel activity	5/5317	28/18639	0.178571428571429	0.62599075740885	0.934178902806415	1
GO:0046625	sphingolipid binding	5/5317	28/18639	0.178571428571429	0.62599075740885	0.934178902806415	1
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	11/5317	54/18639	0.203703703703704	0.714093160303429	0.934792808926494	1
GO:0005244	voltage-gated monoatomic ion channel activity	41/5317	173/18639	0.236994219653179	0.830794669948393	0.934979143362195	1
GO:0070001	aspartic-type peptidase activity	7/5317	37/18639	0.189189189189189	0.663211829470998	0.935573292492128	1
GO:0004890	GABA-A receptor activity	3/5317	19/18639	0.157894736842105	0.553507617077299	0.939426870739191	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/5317	19/18639	0.157894736842105	0.553507617077299	0.939426870739191	1
GO:0034987	immunoglobulin receptor binding	3/5317	19/18639	0.157894736842105	0.553507617077299	0.939426870739191	1
GO:0070003	threonine-type peptidase activity	3/5317	19/18639	0.157894736842105	0.553507617077299	0.939426870739191	1
GO:0097001	ceramide binding	3/5317	19/18639	0.157894736842105	0.553507617077299	0.939426870739191	1
GO:0008474	palmitoyl-(protein) hydrolase activity	2/5317	14/18639	0.142857142857143	0.50079260592708	0.940255820336075	1
GO:0016530	metallochaperone activity	2/5317	14/18639	0.142857142857143	0.50079260592708	0.940255820336075	1
GO:0098599	palmitoyl hydrolase activity	2/5317	14/18639	0.142857142857143	0.50079260592708	0.940255820336075	1
GO:0048027	mRNA 5'-UTR binding	4/5317	24/18639	0.166666666666667	0.58425804024826	0.942238106755202	1
GO:0046873	metal ion transmembrane transporter activity	114/5317	450/18639	0.253333333333333	0.888072221177356	0.943260937569221	1
GO:0008374	O-acyltransferase activity	11/5317	55/18639	0.2	0.701109648297912	0.944090319107114	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	30/5317	132/18639	0.227272727272727	0.796715509429446	0.94532878912985	1
GO:0035250	UDP-galactosyltransferase activity	5/5317	29/18639	0.172413793103448	0.604404869222338	0.946386009830473	1
GO:0015035	protein-disulfide reductase activity	6/5317	34/18639	0.176470588235294	0.618626160262864	0.950924689718516	1
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	6/5317	34/18639	0.176470588235294	0.618626160262864	0.950924689718516	1
GO:0046943	carboxylic acid transmembrane transporter activity	44/5317	188/18639	0.234042553191489	0.820447460774153	0.952193451822047	1
GO:0031418	L-ascorbic acid binding	3/5317	20/18639	0.15	0.525832236223434	0.952578281531952	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/5317	15/18639	0.133333333333333	0.467406432198608	0.95472176208382	1
GO:0016846	carbon-sulfur lyase activity	2/5317	15/18639	0.133333333333333	0.467406432198608	0.95472176208382	1
GO:0055105	ubiquitin-protein transferase inhibitor activity	2/5317	15/18639	0.133333333333333	0.467406432198608	0.95472176208382	1
GO:0140161	monocarboxylate:sodium symporter activity	2/5317	15/18639	0.133333333333333	0.467406432198608	0.95472176208382	1
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	7/5317	39/18639	0.179487179487179	0.629200966421203	0.955432776375412	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	27/5317	122/18639	0.221311475409836	0.775818053444411	0.955441477456368	1
GO:0005342	organic acid transmembrane transporter activity	44/5317	189/18639	0.232804232804233	0.816106468918205	0.956382994874632	1
GO:0015293	symporter activity	33/5317	146/18639	0.226027397260274	0.792349944994216	0.956461459824106	1
GO:0003954	NADH dehydrogenase activity	8/5317	44/18639	0.181818181818182	0.637372407543557	0.959718977463079	1
GO:0016790	thiolester hydrolase activity	8/5317	44/18639	0.181818181818182	0.637372407543557	0.959718977463079	1
GO:0005343	organic acid:sodium symporter activity	6/5317	35/18639	0.171428571428571	0.600951127112496	0.9597467152595	1
GO:0140101	catalytic activity, acting on a tRNA	31/5317	139/18639	0.223021582733813	0.781812917166737	0.960481228258476	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	14/5317	70/18639	0.2	0.701109648297912	0.960911846402408	1
GO:0015125	bile acid transmembrane transporter activity	3/5317	21/18639	0.142857142857143	0.50079260592708	0.963020393866288	1
GO:1904047	S-adenosyl-L-methionine binding	3/5317	21/18639	0.142857142857143	0.50079260592708	0.963020393866288	1
GO:0015036	disulfide oxidoreductase activity	7/5317	40/18639	0.175	0.613470942260673	0.96313054317649	1
GO:0120014	phospholipid transfer activity	4/5317	26/18639	0.153846153846154	0.539315114075317	0.963231579370089	1
GO:0003796	lysozyme activity	1/5317	10/18639	0.1	0.350554824148956	0.965242417491758	1
GO:0004983	neuropeptide Y receptor activity	1/5317	10/18639	0.1	0.350554824148956	0.965242417491758	1
GO:0005337	nucleoside transmembrane transporter activity	1/5317	10/18639	0.1	0.350554824148956	0.965242417491758	1
GO:0015643	toxic substance binding	1/5317	10/18639	0.1	0.350554824148956	0.965242417491758	1
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	1/5317	10/18639	0.1	0.350554824148956	0.965242417491758	1
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/5317	10/18639	0.1	0.350554824148956	0.965242417491758	1
GO:0016868	intramolecular phosphotransferase activity	1/5317	10/18639	0.1	0.350554824148956	0.965242417491758	1
GO:0032052	bile acid binding	1/5317	10/18639	0.1	0.350554824148956	0.965242417491758	1
GO:0042166	acetylcholine binding	1/5317	10/18639	0.1	0.350554824148956	0.965242417491758	1
GO:0047429	nucleoside triphosphate diphosphatase activity	1/5317	10/18639	0.1	0.350554824148956	0.965242417491758	1
GO:0097177	mitochondrial ribosome binding	1/5317	10/18639	0.1	0.350554824148956	0.965242417491758	1
GO:0141109	transporter activator activity	1/5317	10/18639	0.1	0.350554824148956	0.965242417491758	1
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	11/5317	58/18639	0.189655172413793	0.664845356144572	0.965390357225029	1
GO:0000062	fatty-acyl-CoA binding	2/5317	16/18639	0.125	0.438193530186195	0.965797748065085	1
GO:0017070	U6 snRNA binding	2/5317	16/18639	0.125	0.438193530186195	0.965797748065085	1
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	2/5317	16/18639	0.125	0.438193530186195	0.965797748065085	1
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	2/5317	16/18639	0.125	0.438193530186195	0.965797748065085	1
GO:0008514	organic anion transmembrane transporter activity	64/5317	269/18639	0.237918215613383	0.834033782361829	0.965924593059666	1
GO:0046915	transition metal ion transmembrane transporter activity	8/5317	45/18639	0.177777777777778	0.623208576264811	0.966446930798006	1
GO:0004190	aspartic-type endopeptidase activity	6/5317	36/18639	0.166666666666667	0.58425804024826	0.967100853246081	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	6/5317	36/18639	0.166666666666667	0.58425804024826	0.967100853246081	1
GO:0140318	protein transporter activity	7/5317	41/18639	0.170731707317073	0.598508236351876	0.969601202447831	1
GO:0005385	zinc ion transmembrane transporter activity	4/5317	27/18639	0.148148148148148	0.519340480220676	0.970830749031265	1
GO:0015252	proton channel activity	4/5317	27/18639	0.148148148148148	0.519340480220676	0.970830749031265	1
GO:0008649	rRNA methyltransferase activity	3/5317	22/18639	0.136363636363636	0.478029305657667	0.971267531928536	1
GO:0015106	bicarbonate transmembrane transporter activity	5/5317	32/18639	0.15625	0.547741912732744	0.971690725008655	1
GO:0022884	macromolecule transmembrane transporter activity	5/5317	32/18639	0.15625	0.547741912732744	0.971690725008655	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	8/5317	46/18639	0.173913043478261	0.609660563737315	0.972139399084964	1
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	13/5317	68/18639	0.191176470588235	0.670178340284769	0.972303726579267	1
GO:0015276	ligand-gated monoatomic ion channel activity	42/5317	186/18639	0.225806451612903	0.791575409368611	0.972591030196649	1
GO:0004549	tRNA-specific ribonuclease activity	2/5317	17/18639	0.117647058823529	0.412417440175243	0.974240310283915	1
GO:0051787	misfolded protein binding	2/5317	17/18639	0.117647058823529	0.412417440175243	0.974240310283915	1
GO:1901567	fatty acid derivative binding	2/5317	17/18639	0.117647058823529	0.412417440175243	0.974240310283915	1
GO:0016859	cis-trans isomerase activity	7/5317	42/18639	0.166666666666667	0.58425804024826	0.975016941369528	1
GO:0051879	Hsp90 protein binding	7/5317	42/18639	0.166666666666667	0.58425804024826	0.975016941369528	1
GO:0004523	RNA-DNA hybrid ribonuclease activity	1/5317	11/18639	0.0909090909090909	0.318686203771778	0.975162760301159	1
GO:0008503	benzodiazepine receptor activity	1/5317	11/18639	0.0909090909090909	0.318686203771778	0.975162760301159	1
GO:0016594	glycine binding	1/5317	11/18639	0.0909090909090909	0.318686203771778	0.975162760301159	1
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	1/5317	11/18639	0.0909090909090909	0.318686203771778	0.975162760301159	1
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/5317	11/18639	0.0909090909090909	0.318686203771778	0.975162760301159	1
GO:0031731	CCR6 chemokine receptor binding	1/5317	11/18639	0.0909090909090909	0.318686203771778	0.975162760301159	1
GO:0034511	U3 snoRNA binding	1/5317	11/18639	0.0909090909090909	0.318686203771778	0.975162760301159	1
GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/5317	11/18639	0.0909090909090909	0.318686203771778	0.975162760301159	1
GO:1990948	ubiquitin ligase inhibitor activity	1/5317	11/18639	0.0909090909090909	0.318686203771778	0.975162760301159	1
GO:0022834	ligand-gated channel activity	42/5317	188/18639	0.223404255319149	0.783154394375328	0.977633907612207	1
GO:0008171	O-methyltransferase activity	3/5317	23/18639	0.130434782608696	0.457245422802986	0.977749932175961	1
GO:0140102	catalytic activity, acting on a rRNA	3/5317	23/18639	0.130434782608696	0.457245422802986	0.977749932175961	1
GO:0009055	electron transfer activity	24/5317	116/18639	0.206896551724138	0.725285843066806	0.978815440260725	1
GO:0003746	translation elongation factor activity	2/5317	18/18639	0.111111111111111	0.389505360165507	0.980650295726473	1
GO:0008409	5'-3' exonuclease activity	2/5317	18/18639	0.111111111111111	0.389505360165507	0.980650295726473	1
GO:0016854	racemase and epimerase activity	2/5317	18/18639	0.111111111111111	0.389505360165507	0.980650295726473	1
GO:0016835	carbon-oxygen lyase activity	15/5317	79/18639	0.189873417721519	0.665610425599284	0.981008071516055	1
GO:0015020	glucuronosyltransferase activity	5/5317	34/18639	0.147058823529412	0.515521800219053	0.981823369159406	1
GO:0003720	telomerase activity	1/5317	12/18639	0.0833333333333333	0.29212902012413	0.982252066908349	1
GO:0004032	aldose reductase (NADPH) activity	1/5317	12/18639	0.0833333333333333	0.29212902012413	0.982252066908349	1
GO:0005436	sodium:phosphate symporter activity	1/5317	12/18639	0.0833333333333333	0.29212902012413	0.982252066908349	1
GO:0010853	cyclase activator activity	1/5317	12/18639	0.0833333333333333	0.29212902012413	0.982252066908349	1
GO:0042625	ATPase-coupled ion transmembrane transporter activity	3/5317	24/18639	0.125	0.438193530186195	0.982823050093212	1
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	3/5317	24/18639	0.125	0.438193530186195	0.982823050093212	1
GO:0046961	proton-transporting ATPase activity, rotational mechanism	3/5317	24/18639	0.125	0.438193530186195	0.982823050093212	1
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	9/5317	54/18639	0.166666666666667	0.58425804024826	0.985452106513439	1
GO:0003756	protein disulfide isomerase activity	2/5317	19/18639	0.105263157894737	0.369005078051533	0.985500110430859	1
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	2/5317	19/18639	0.105263157894737	0.369005078051533	0.985500110430859	1
GO:0099589	serotonin receptor activity	2/5317	19/18639	0.105263157894737	0.369005078051533	0.985500110430859	1
GO:0120227	acyl-CoA binding	2/5317	19/18639	0.105263157894737	0.369005078051533	0.985500110430859	1
GO:0071855	neuropeptide receptor binding	6/5317	40/18639	0.15	0.525832236223434	0.98579064330597	1
GO:0005537	D-mannose binding	3/5317	25/18639	0.12	0.420665788978747	0.986777488092911	1
GO:0015662	P-type ion transporter activity	3/5317	25/18639	0.12	0.420665788978747	0.986777488092911	1
GO:0140358	P-type transmembrane transporter activity	3/5317	25/18639	0.12	0.420665788978747	0.986777488092911	1
GO:0002161	aminoacyl-tRNA editing activity	1/5317	13/18639	0.0769230769230769	0.269657557037659	0.987318140900313	1
GO:0003964	RNA-directed DNA polymerase activity	1/5317	13/18639	0.0769230769230769	0.269657557037659	0.987318140900313	1
GO:0008417	fucosyltransferase activity	1/5317	13/18639	0.0769230769230769	0.269657557037659	0.987318140900313	1
GO:0015294	solute:monoatomic cation symporter activity	23/5317	116/18639	0.198275862068966	0.695065599605689	0.987859800223007	1
GO:0004812	aminoacyl-tRNA ligase activity	6/5317	41/18639	0.146341463414634	0.51300705973018	0.988565976024508	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	6/5317	41/18639	0.146341463414634	0.51300705973018	0.988565976024508	1
GO:0015399	primary active transmembrane transporter activity	35/5317	166/18639	0.210843373493976	0.739121617181534	0.988586605458884	1
GO:0098960	postsynaptic neurotransmitter receptor activity	12/5317	69/18639	0.173913043478261	0.609660563737315	0.988736876766791	1
GO:0005184	neuropeptide hormone activity	4/5317	31/18639	0.129032258064516	0.452328805353492	0.988816766861615	1
GO:0005326	neurotransmitter transmembrane transporter activity	2/5317	20/18639	0.1	0.350554824148956	0.989158091419627	1
GO:0030627	pre-mRNA 5'-splice site binding	2/5317	20/18639	0.1	0.350554824148956	0.989158091419627	1
GO:0019843	rRNA binding	11/5317	65/18639	0.169230769230769	0.593246625482849	0.989721882643638	1
GO:0022836	gated channel activity	73/5317	318/18639	0.229559748427673	0.804732772417415	0.989909328798568	1
GO:0022804	active transmembrane transporter activity	109/5317	457/18639	0.238512035010941	0.836115444906701	0.990024907109044	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	9/5317	56/18639	0.160714285714286	0.563391681667965	0.990096810277106	1
GO:0015370	solute:sodium symporter activity	14/5317	79/18639	0.177215189873418	0.621236397225998	0.990655065003856	1
GO:0022829	wide pore channel activity	5/5317	37/18639	0.135135135135135	0.473722735336427	0.990856479798207	1
GO:0061783	peptidoglycan muralytic activity	1/5317	14/18639	0.0714285714285714	0.25039630296354	0.990938319405254	1
GO:0099095	ligand-gated monoatomic anion channel activity	7/5317	47/18639	0.148936170212766	0.522102929583552	0.991036231767718	1
GO:0160041	neuropeptide activity	4/5317	32/18639	0.125	0.438193530186195	0.99126334426918	1
GO:0015078	proton transmembrane transporter activity	39/5317	185/18639	0.210810810810811	0.739007467124827	0.99173046745242	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	8/5317	53/18639	0.150943396226415	0.529139357205972	0.992996170377505	1
GO:0140223	general transcription initiation factor activity	11/5317	68/18639	0.161764705882353	0.567073980240959	0.994107539208933	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	12/5317	73/18639	0.164383561643836	0.576254505450339	0.994519899979871	1
GO:0005149	interleukin-1 receptor binding	1/5317	16/18639	0.0625	0.219096765093098	0.995373714242898	1
GO:0032977	membrane insertase activity	1/5317	17/18639	0.0588235294117647	0.206208720087621	0.996694551990335	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	7/5317	52/18639	0.134615384615385	0.471900724815903	0.996981928000432	1
GO:0031492	nucleosomal DNA binding	5/5317	42/18639	0.119047619047619	0.4173271716059	0.997235370997239	1
GO:0022853	active monoatomic ion transmembrane transporter activity	21/5317	118/18639	0.177966101694915	0.623868754841363	0.99751656371044	1
GO:0030280	structural constituent of skin epidermis	4/5317	37/18639	0.108108108108108	0.378978188269142	0.997547194240025	1
GO:0022824	transmitter-gated monoatomic ion channel activity	9/5317	63/18639	0.142857142857143	0.50079260592708	0.997604091419279	1
GO:0022835	transmitter-gated channel activity	9/5317	63/18639	0.142857142857143	0.50079260592708	0.997604091419279	1
GO:0005179	hormone activity	24/5317	132/18639	0.181818181818182	0.637372407543557	0.997829220558821	1
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	8/5317	60/18639	0.133333333333333	0.467406432198608	0.998433365840268	1
GO:0042923	neuropeptide binding	3/5317	33/18639	0.0909090909090909	0.318686203771778	0.99849958936804	1
GO:0008320	protein transmembrane transporter activity	2/5317	27/18639	0.0740740740740741	0.259670240110338	0.998649564979831	1
GO:0008527	taste receptor activity	2/5317	28/18639	0.0714285714285714	0.25039630296354	0.999002583652412	1
GO:0051537	2 iron, 2 sulfur cluster binding	2/5317	28/18639	0.0714285714285714	0.25039630296354	0.999002583652412	1
GO:0030594	neurotransmitter receptor activity	15/5317	97/18639	0.154639175257732	0.542095088890138	0.999162792259889	1
GO:0016860	intramolecular oxidoreductase activity	6/5317	53/18639	0.113207547169811	0.396854517904479	0.999298156869743	1
GO:0033038	bitter taste receptor activity	1/5317	22/18639	0.0454545454545455	0.159343101885889	0.999384709943227	1
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	2/5317	33/18639	0.0606060606060606	0.212457469181186	0.999784080241011	1
GO:0008188	neuropeptide receptor activity	4/5317	48/18639	0.0833333333333333	0.29212902012413	0.999872258482636	1
GO:0004033	aldo-keto reductase (NADPH) activity	2/5317	36/18639	0.0555555555555556	0.194752680082753	0.999914669021331	1
GO:0016866	intramolecular transferase activity	1/5317	28/18639	0.0357142857142857	0.12519815148177	0.999918230446003	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	1/5317	30/18639	0.0333333333333333	0.116851608049652	0.999958279046447	1
GO:0016853	isomerase activity	29/5317	180/18639	0.161111111111111	0.564782772239985	0.99996828898858	1
GO:0003730	mRNA 3'-UTR binding	47/5317	262/18639	0.179389312977099	0.628857890648891	0.999975969417568	1
GO:0003823	antigen binding	22/5317	174/18639	0.126436781609195	0.443230237429715	0.999999852094781	1
GO:0003735	structural constituent of ribosome	14/5317	175/18639	0.08	0.280443859319165	0.999999999997028	1
GO:0030371	translation repressor activity	13/5317	329/18639	0.0395136778115502	0.138517103767065	1	1
GO:0045182	translation regulator activity	18/5317	356/18639	0.050561797752809	0.17724682119891	1	1