ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003712	transcription coregulator activity	52/649	495/18639	0.105050505050505	3.01700518279871	1.22041215636178e-12	1.10081176503832e-09
GO:0140297	DNA-binding transcription factor binding	50/649	488/18639	0.102459016393443	2.94257874662154	8.51060056533529e-12	3.83828085496622e-09
GO:0004674	protein serine/threonine kinase activity	45/649	433/18639	0.103926096997691	2.98471266862859	6.08925376427399e-11	1.83083563179171e-08
GO:0106310	protein serine kinase activity	40/649	361/18639	0.110803324099723	3.18222366393642	1.05917602160254e-10	2.38844192871372e-08
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	37/649	349/18639	0.106017191977077	3.04476801426925	1.84754486326919e-09	3.33297093333762e-07
GO:0045296	cadherin binding	34/649	334/18639	0.101796407185629	2.92354889604458	2.3472533319468e-08	3.52870417569335e-06
GO:0140857	histone H3T45 kinase activity	27/649	246/18639	0.109756097560976	3.15214776955166	1.44079713203429e-07	1.70822498589187e-05
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	26/649	243/18639	0.106995884773663	3.07287564914684	4.03664437375088e-07	1.70822498589187e-05
GO:0004676	3-phosphoinositide-dependent protein kinase activity	26/649	245/18639	0.106122448979592	3.04779094997013	4.73454818706173e-07	1.70822498589187e-05
GO:0004711	ribosomal protein S6 kinase activity	26/649	245/18639	0.106122448979592	3.04779094997013	4.73454818706173e-07	1.70822498589187e-05
GO:0035175	histone H3S10 kinase activity	26/649	245/18639	0.106122448979592	3.04779094997013	4.73454818706173e-07	1.70822498589187e-05
GO:0035979	histone H2AXS139 kinase activity	26/649	245/18639	0.106122448979592	3.04779094997013	4.73454818706173e-07	1.70822498589187e-05
GO:0044022	histone H3S28 kinase activity	26/649	245/18639	0.106122448979592	3.04779094997013	4.73454818706173e-07	1.70822498589187e-05
GO:0044023	histone H4S1 kinase activity	26/649	245/18639	0.106122448979592	3.04779094997013	4.73454818706173e-07	1.70822498589187e-05
GO:0044024	histone H2AS1 kinase activity	26/649	245/18639	0.106122448979592	3.04779094997013	4.73454818706173e-07	1.70822498589187e-05
GO:0044025	histone H2BS14 kinase activity	26/649	245/18639	0.106122448979592	3.04779094997013	4.73454818706173e-07	1.70822498589187e-05
GO:0072354	histone H3T3 kinase activity	26/649	245/18639	0.106122448979592	3.04779094997013	4.73454818706173e-07	1.70822498589187e-05
GO:0072371	histone H2AS121 kinase activity	26/649	245/18639	0.106122448979592	3.04779094997013	4.73454818706173e-07	1.70822498589187e-05
GO:0072518	Rho-dependent protein serine/threonine kinase activity	26/649	245/18639	0.106122448979592	3.04779094997013	4.73454818706173e-07	1.70822498589187e-05
GO:0140823	histone H2BS36 kinase activity	26/649	245/18639	0.106122448979592	3.04779094997013	4.73454818706173e-07	1.70822498589187e-05
GO:0140855	histone H3S57 kinase activity	26/649	245/18639	0.106122448979592	3.04779094997013	4.73454818706173e-07	1.70822498589187e-05
GO:0140995	histone H2A kinase activity	26/649	245/18639	0.106122448979592	3.04779094997013	4.73454818706173e-07	1.70822498589187e-05
GO:0140997	histone H4 kinase activity	26/649	245/18639	0.106122448979592	3.04779094997013	4.73454818706173e-07	1.70822498589187e-05
GO:0140998	histone H2B kinase activity	26/649	245/18639	0.106122448979592	3.04779094997013	4.73454818706173e-07	1.70822498589187e-05
GO:1990244	histone H2AT120 kinase activity	26/649	245/18639	0.106122448979592	3.04779094997013	4.73454818706173e-07	1.70822498589187e-05
GO:0004677	DNA-dependent protein kinase activity	26/649	246/18639	0.105691056910569	3.03540155586456	5.12380967538313e-07	1.77756781815215e-05
GO:0035402	histone H3T11 kinase activity	26/649	247/18639	0.105263157894737	3.0231124807396	5.54242886168044e-07	1.78545386901277e-05
GO:0035403	histone H3T6 kinase activity	26/649	247/18639	0.105263157894737	3.0231124807396	5.54242886168044e-07	1.78545386901277e-05
GO:0004679	AMP-activated protein kinase activity	26/649	248/18639	0.104838709677419	3.0109225110592	5.99241292921594e-07	1.86384705591475e-05
GO:0003713	transcription coactivator activity	26/649	256/18639	0.1015625	2.9168311825886	1.1005792480469e-06	3.30907493912767e-05
GO:0141003	histone H2AX kinase activity	31/649	354/18639	0.0875706214689266	2.51499046773393	2.58529982686778e-06	7.52238852849914e-05
GO:0140996	histone H3 kinase activity	31/649	357/18639	0.0868347338935574	2.4938560940555	3.07997298668213e-06	8.68167385621025e-05
GO:0035173	histone kinase activity	31/649	360/18639	0.0861111111111111	2.47307395993837	3.66055703529888e-06	0.000100055225631503
GO:0001217	DNA-binding transcription repressor activity	26/649	278/18639	0.0935251798561151	2.68600281562115	5.09387156819348e-06	0.000135137416309133
GO:0032452	histone demethylase activity	8/649	30/18639	0.266666666666667	7.65855161787365	6.14008757824712e-06	0.000158238828445111
GO:0032451	demethylase activity	9/649	40/18639	0.225	6.46190292758089	7.39514187470599e-06	0.000185289388082911
GO:0031625	ubiquitin protein ligase binding	27/649	302/18639	0.0894039735099338	2.56764354738314	7.78590361335546e-06	0.000189807704303963
GO:0140457	protein demethylase activity	8/649	31/18639	0.258064516129032	7.41150156568418	8.02473216162544e-06	0.00019048180025753
GO:0044389	ubiquitin-like protein ligase binding	28/649	322/18639	0.0869565217391304	2.49735378843706	8.95771399057971e-06	0.000207175846653921
GO:0003714	transcription corepressor activity	21/649	204/18639	0.102941176470588	2.9564261760174	9.52404929892305e-06	0.000214767311690715
GO:0035591	signaling adaptor activity	16/649	129/18639	0.124031007751938	3.56211703156914	1.07235941554073e-05	0.000235919071418961
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	24/649	268/18639	0.0895522388059701	2.57190166271876	2.39740215870607e-05	0.000514870654084019
GO:0000993	RNA polymerase II complex binding	8/649	36/18639	0.222222222222222	6.38212634822804	2.63930673305717e-05	0.000553640621678505
GO:0004386	helicase activity	17/649	155/18639	0.109677419354839	3.14988816541578	2.94181540934475e-05	0.000603072158915674
GO:0019787	ubiquitin-like protein transferase activity	35/649	479/18639	0.0730688935281837	2.09850709779941	3.19329510305508e-05	0.000640078262879041
GO:0051019	mitogen-activated protein kinase binding	7/649	28/18639	0.25	7.17989214175655	3.75511836096871e-05	0.000703985662748085
GO:0141052	histone H3 demethylase activity	7/649	28/18639	0.25	7.17989214175655	3.75511836096871e-05	0.000703985662748085
GO:0001098	basal transcription machinery binding	10/649	60/18639	0.166666666666667	4.78659476117103	3.82431235860933e-05	0.000703985662748085
GO:0001099	basal RNA polymerase II transcription machinery binding	10/649	60/18639	0.166666666666667	4.78659476117103	3.82431235860933e-05	0.000703985662748085
GO:0031490	chromatin DNA binding	15/649	128/18639	0.1171875	3.36557444144838	3.95658307173513e-05	0.000713767586141017
GO:0001221	transcription coregulator binding	14/649	115/18639	0.121739130434783	3.49629530381188	4.65270562794157e-05	0.000822890289490843
GO:0009931	calcium-dependent protein serine/threonine kinase activity	6/649	21/18639	0.285714285714286	8.20559101915034	6.03909546153084e-05	0.00104755078967323
GO:0016755	aminoacyltransferase activity	35/649	496/18639	0.0705645161290323	2.02658245936677	6.48545714352185e-05	0.00110375138555787
GO:0043175	RNA polymerase core enzyme binding	8/649	42/18639	0.19047619047619	5.47039401276689	8.5629625394813e-05	0.00141836683256238
GO:0016922	nuclear receptor binding	15/649	137/18639	0.109489051094891	3.14447831025834	8.71282698367743e-05	0.00141836683256238
GO:0046332	SMAD binding	11/649	79/18639	0.139240506329114	3.99892726882643	8.80582512455576e-05	0.00141836683256238
GO:0140313	molecular sequestering activity	9/649	55/18639	0.163636363636364	4.69956576551338	0.000107958759303453	0.00170840001564411
GO:0004842	ubiquitin-protein transferase activity	32/649	449/18639	0.0712694877505568	2.04682894018895	0.000110096327722146	0.00171218771733406
GO:0140311	protein sequestering activity	7/649	33/18639	0.212121212121212	6.09202969603586	0.000116454957994282	0.00177847904040858
GO:0051020	GTPase binding	25/649	315/18639	0.0793650793650794	2.27933083865287	0.000118302375193476	0.00177847904040858
GO:0016887	ATP hydrolysis activity	30/649	417/18639	0.0719424460431655	2.06615601201627	0.000151941427441906	0.00221173522908885
GO:0019903	protein phosphatase binding	15/649	144/18639	0.104166666666667	2.9916217257319	0.000153112548844016	0.00221173522908885
GO:0031267	small GTPase binding	23/649	283/18639	0.0812720848056537	2.33409921216114	0.000154478181189133	0.00221173522908885
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	5/649	16/18639	0.3125	8.97486517719569	0.000159915701440295	0.00225381191717415
GO:0061631	ubiquitin conjugating enzyme activity	7/649	35/18639	0.2	5.74391371340524	0.000172559055942368	0.00239178495136693
GO:0008139	nuclear localization sequence binding	6/649	25/18639	0.24	6.89269645608629	0.000175008654978068	0.00239178495136693
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	33/649	484/18639	0.0681818181818182	1.95815240229724	0.000197534034093437	0.00265933878734746
GO:0001216	DNA-binding transcription activator activity	33/649	491/18639	0.0672097759674134	1.9302357692706	0.000256512333480246	0.00338084545900646
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	4/649	10/18639	0.4	11.4878274268105	0.000258623433116902	0.00338084545900646
GO:0003725	double-stranded RNA binding	10/649	75/18639	0.133333333333333	3.82927580893683	0.00026329975979547	0.00339280547622163
GO:0061775	cohesin loader activity	15/649	153/18639	0.0980392156862745	2.81564397715943	0.000298623060877763	0.00379377466072876
GO:0140597	protein carrier chaperone	17/649	188/18639	0.0904255319148936	2.5969822640396	0.000319566740480043	0.00400346110990276
GO:0019888	protein phosphatase regulator activity	12/649	107/18639	0.11214953271028	3.22088619443284	0.000347343046563153	0.00429182778082142
GO:0019902	phosphatase binding	17/649	190/18639	0.0894736842105263	2.56964560862866	0.00036170124271209	0.0044088448773825
GO:0140658	ATP-dependent chromatin remodeler activity	15/649	158/18639	0.0949367088607595	2.72654131965439	0.000422128301127687	0.00507679636822899
GO:0140104	molecular carrier activity	20/649	249/18639	0.0803212851405622	2.30679265598604	0.000473005547420272	0.00561382899701428
GO:0061650	ubiquitin-like protein conjugating enzyme activity	7/649	41/18639	0.170731707317073	4.90334097485813	0.000481443910956628	0.00563977152834907
GO:0051721	protein phosphatase 2A binding	6/649	30/18639	0.2	5.74391371340524	0.00050598241059699	0.00585123249177545
GO:1990841	promoter-specific chromatin binding	9/649	68/18639	0.132352941176471	3.80111936916523	0.000560085327571717	0.00632084130997789
GO:0004402	histone acetyltransferase activity	7/649	42/18639	0.166666666666667	4.78659476117103	0.000560606768068992	0.00632084130997789
GO:1990247	N6-methyladenosine-containing RNA reader activity	4/649	12/18639	0.333333333333333	9.57318952234206	0.000576567805334268	0.00642054519026555
GO:0019209	kinase activator activity	14/649	148/18639	0.0945945945945946	2.71671594552951	0.000673091975036739	0.00740401172540413
GO:0043130	ubiquitin binding	11/649	100/18639	0.11	3.15915254237288	0.000714664892582613	0.00776659919409057
GO:0051059	NF-kappaB binding	6/649	32/18639	0.1875	5.38491910631741	0.000727889189795288	0.00781614344280178
GO:0019208	phosphatase regulator activity	12/649	117/18639	0.102564102564103	2.94559677610525	0.000784130901819202	0.00822996862997331
GO:0050321	tau-protein kinase activity	5/649	22/18639	0.227272727272727	6.52717467432413	0.000810676106523978	0.00822996862997331
GO:0000510	H3-H4 histone complex chaperone activity	14/649	151/18639	0.0927152317880795	2.66274145654547	0.000821172036250108	0.00822996862997331
GO:0140584	chromatin extrusion motor activity	14/649	151/18639	0.0927152317880795	2.66274145654547	0.000821172036250108	0.00822996862997331
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	14/649	151/18639	0.0927152317880795	2.66274145654547	0.000821172036250108	0.00822996862997331
GO:0140849	ATP-dependent H2AZ histone chaperone activity	14/649	151/18639	0.0927152317880795	2.66274145654547	0.000821172036250108	0.00822996862997331
GO:0042605	peptide antigen binding	7/649	45/18639	0.155555555555556	4.46748844375963	0.000861673836139186	0.00840845099673823
GO:0071889	14-3-3 protein binding	6/649	33/18639	0.181818181818182	5.22173973945931	0.000863763463528847	0.00840845099673823
GO:0015616	DNA translocase activity	14/649	152/18639	0.0921052631578947	2.64522342064715	0.000876268729150104	0.00840845099673823
GO:0140674	ATP-dependent histone chaperone activity	14/649	152/18639	0.0921052631578947	2.64522342064715	0.000876268729150104	0.00840845099673823
GO:0045309	protein phosphorylated amino acid binding	8/649	59/18639	0.135593220338983	3.89417878874931	0.000957231801491822	0.00899399046818358
GO:0070063	RNA polymerase binding	8/649	59/18639	0.135593220338983	3.89417878874931	0.000957231801491822	0.00899399046818358
GO:0032182	ubiquitin-like protein binding	12/649	120/18639	0.1	2.87195685670262	0.000981696864697948	0.00912876878306751
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	8/649	60/18639	0.133333333333333	3.82927580893683	0.00107141464442351	0.00986138784969392
GO:0042393	histone binding	19/649	247/18639	0.0769230769230769	2.20919758207894	0.00108906815469704	0.00992262096501748
GO:0008094	ATP-dependent activity, acting on DNA	17/649	210/18639	0.080952380952381	2.32491745542593	0.00112343711810636	0.00994512962848274
GO:0061733	protein-lysine-acetyltransferase activity	7/649	47/18639	0.148936170212766	4.27738255253582	0.00112461554557122	0.00994512962848274
GO:0140938	histone H3 methyltransferase activity	7/649	47/18639	0.148936170212766	4.27738255253582	0.00112461554557122	0.00994512962848274
GO:0010485	histone H4 acetyltransferase activity	6/649	35/18639	0.171428571428571	4.9233546114902	0.00119336156384911	0.0104506032096301
GO:0140693	molecular condensate scaffold activity	7/649	48/18639	0.145833333333333	4.18827041602465	0.00127772654530718	0.0110818206141065
GO:0061659	ubiquitin-like protein ligase activity	25/649	372/18639	0.0672043010752688	1.93007853273025	0.00138514159054456	0.0118990258540113
GO:0003689	DNA clamp loader activity	14/649	160/18639	0.0875	2.51296224961479	0.00143988000506497	0.0121049733293386
GO:0001222	transcription corepressor binding	7/649	49/18639	0.142857142857143	4.10279550957517	0.00144666785080898	0.0121049733293386
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	4/649	15/18639	0.266666666666667	7.65855161787365	0.00146279611186021	0.0121049733293386
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	4/649	15/18639	0.266666666666667	7.65855161787365	0.00146279611186021	0.0121049733293386
GO:0050681	nuclear androgen receptor binding	5/649	26/18639	0.192307692307692	5.52299395519735	0.00180495643477879	0.0147845076283979
GO:0140713	histone chaperone activity	14/649	164/18639	0.0853658536585366	2.45167048742907	0.00181937954185385	0.0147845076283979
GO:0005048	signal sequence binding	7/649	51/18639	0.137254901960784	3.9419015680232	0.0018364508712453	0.0147899882666363
GO:0030275	LRR domain binding	4/649	16/18639	0.25	7.17989214175655	0.00189708958200017	0.0151431398492403
GO:0042054	histone methyltransferase activity	8/649	67/18639	0.119402985074627	3.42920221695835	0.00220844179307979	0.0174738113803331
GO:0034212	protein N-acetyltransferase activity	7/649	53/18639	0.132075471698113	3.79315056545629	0.00230308966417803	0.0180642337138138
GO:0036408	histone H3K14 acetyltransferase activity	5/649	28/18639	0.178571428571429	5.12849438696896	0.00254641489983256	0.0198005710314567
GO:0002039	p53 binding	8/649	69/18639	0.115942028985507	3.32980505124941	0.00266476775169546	0.0205437650600795
GO:0003924	GTPase activity	22/649	331/18639	0.0664652567975831	1.90885349992319	0.00298837443961862	0.022664118820534
GO:0010484	histone H3 acetyltransferase activity	5/649	29/18639	0.172413793103448	4.95164975293555	0.00299005558718797	0.022664118820534
GO:0061630	ubiquitin protein ligase activity	23/649	353/18639	0.0651558073654391	1.87124667717168	0.00311750084683906	0.0234332146987403
GO:0030295	protein kinase activator activity	12/649	139/18639	0.0863309352517986	2.47938721441953	0.00342314418532113	0.0251612555256045
GO:0035925	mRNA 3'-UTR AU-rich region binding	5/649	30/18639	0.166666666666667	4.78659476117103	0.00348687022250617	0.0251612555256045
GO:0043995	histone H4K5 acetyltransferase activity	5/649	30/18639	0.166666666666667	4.78659476117103	0.00348687022250617	0.0251612555256045
GO:0043996	histone H4K8 acetyltransferase activity	5/649	30/18639	0.166666666666667	4.78659476117103	0.00348687022250617	0.0251612555256045
GO:0043997	histone H4K12 acetyltransferase activity	5/649	30/18639	0.166666666666667	4.78659476117103	0.00348687022250617	0.0251612555256045
GO:0003727	single-stranded RNA binding	9/649	89/18639	0.101123595505618	2.90422603486782	0.00379405254724772	0.0271605983937892
GO:0001223	transcription coactivator binding	6/649	44/18639	0.136363636363636	3.91630480459448	0.00398437897371726	0.0282985026322281
GO:0031996	thioesterase binding	3/649	10/18639	0.3	8.61587057010786	0.0041981039957318	0.0293541845282952
GO:0051864	histone H3K36 demethylase activity	3/649	10/18639	0.3	8.61587057010786	0.0041981039957318	0.0293541845282952
GO:0042826	histone deacetylase binding	11/649	127/18639	0.0866141732283465	2.48752168690778	0.00484582645859375	0.033622580505012
GO:0051213	dioxygenase activity	9/649	93/18639	0.0967741935483871	2.77931308713157	0.00508180925647081	0.0347256965858838
GO:0051219	phosphoprotein binding	9/649	93/18639	0.0967741935483871	2.77931308713157	0.00508180925647081	0.0347256965858838
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	11/649	128/18639	0.0859375	2.46808792372881	0.00513978499702573	0.0348577899798286
GO:0003724	RNA helicase activity	8/649	77/18639	0.103896103896104	2.98385127969103	0.00526653954257947	0.0354508855776618
GO:0140416	transcription regulator inhibitor activity	5/649	33/18639	0.151515151515152	4.35144978288276	0.00533045690349692	0.0356153490885498
GO:0001784	phosphotyrosine residue binding	6/649	47/18639	0.127659574468085	3.66632790217356	0.00555173795162264	0.03676094805002
GO:0008432	JUN kinase binding	3/649	11/18639	0.272727272727273	7.83260960918896	0.00562418052206514	0.03676094805002
GO:0043522	leucine zipper domain binding	3/649	11/18639	0.272727272727273	7.83260960918896	0.00562418052206514	0.03676094805002
GO:0019207	kinase regulator activity	19/649	287/18639	0.0662020905923345	1.90129548004703	0.00579704497648484	0.0376182343078368
GO:0008186	ATP-dependent activity, acting on RNA	8/649	79/18639	0.10126582278481	2.90831074096468	0.00614788006281363	0.0396099129761278
GO:0016407	acetyltransferase activity	9/649	96/18639	0.09375	2.69245955315871	0.00625217173599774	0.0399961624529785
GO:0140517	protein-RNA adaptor activity	4/649	22/18639	0.181818181818182	5.22173973945931	0.00646166010784844	0.0410451930794316
GO:0005078	MAP-kinase scaffold activity	3/649	12/18639	0.25	7.17989214175655	0.00730671809430877	0.0449540052209148
GO:0034452	dynactin binding	3/649	12/18639	0.25	7.17989214175655	0.00730671809430877	0.0449540052209148
GO:0035259	nuclear glucocorticoid receptor binding	3/649	12/18639	0.25	7.17989214175655	0.00730671809430877	0.0449540052209148
GO:1990817	poly(A) RNA polymerase activity	3/649	12/18639	0.25	7.17989214175655	0.00730671809430877	0.0449540052209148
GO:0140097	catalytic activity, acting on DNA	21/649	336/18639	0.0625	1.79497303543914	0.00732620705928433	0.0449540052209148
GO:0016779	nucleotidyltransferase activity	11/649	136/18639	0.0808823529411765	2.32290628115653	0.00803077583826941	0.0489443230143176
GO:0023023	MHC protein complex binding	5/649	37/18639	0.135135135135135	3.88102277932786	0.0087368303296647	0.0528900735393125
GO:0140033	acetylation-dependent protein binding	4/649	24/18639	0.166666666666667	4.78659476117103	0.00888509628377629	0.0534290456531081
GO:0004535	poly(A)-specific ribonuclease activity	3/649	13/18639	0.230769230769231	6.62759274623681	0.00925574100212082	0.0552892608206158
GO:0008080	N-acetyltransferase activity	7/649	69/18639	0.101449275362319	2.91357941984324	0.0100165458514977	0.0590517931898751
GO:0016279	protein-lysine N-methyltransferase activity	7/649	69/18639	0.101449275362319	2.91357941984324	0.0100165458514977	0.0590517931898751
GO:0042974	nuclear retinoic acid receptor binding	4/649	25/18639	0.16	4.59513097072419	0.0102917198107942	0.0602800731775086
GO:0016278	lysine N-methyltransferase activity	7/649	70/18639	0.1	2.87195685670262	0.0108051695442713	0.0628791156705335
GO:0004705	JUN kinase activity	3/649	14/18639	0.214285714285714	6.15419326436276	0.0114792438987169	0.0659508152652399
GO:0044548	S100 protein binding	3/649	14/18639	0.214285714285714	6.15419326436276	0.0114792438987169	0.0659508152652399
GO:0005160	transforming growth factor beta receptor binding	4/649	26/18639	0.153846153846154	4.41839516415788	0.0118347676973424	0.0671381161195147
GO:0070412	R-SMAD binding	4/649	26/18639	0.153846153846154	4.41839516415788	0.0118347676973424	0.0671381161195147
GO:0015293	symporter activity	11/649	146/18639	0.0753424657534247	2.1638031112143	0.0132607979758781	0.0747577485890126
GO:0001671	ATPase activator activity	4/649	27/18639	0.148148148148148	4.25475089881869	0.0135186366039808	0.0748086516367525
GO:0008266	poly(U) RNA binding	4/649	27/18639	0.148148148148148	4.25475089881869	0.0135186366039808	0.0748086516367525
GO:0023026	MHC class II protein complex binding	4/649	27/18639	0.148148148148148	4.25475089881869	0.0135186366039808	0.0748086516367525
GO:0061578	K63-linked deubiquitinase activity	3/649	15/18639	0.2	5.74391371340524	0.0139833558454311	0.0762206803962134
GO:0120283	protein serine/threonine kinase binding	3/649	15/18639	0.2	5.74391371340524	0.0139833558454311	0.0762206803962134
GO:0016504	peptidase activator activity	6/649	57/18639	0.105263157894737	3.0231124807396	0.0140273092525182	0.0762206803962134
GO:0035198	miRNA binding	5/649	42/18639	0.119047619047619	3.41899625797931	0.014798723527236	0.0799308300692625
GO:0061980	regulatory RNA binding	6/649	58/18639	0.103448275862069	2.97098985176133	0.0151993397943887	0.0816059791341586
GO:0046966	nuclear thyroid hormone receptor binding	4/649	28/18639	0.142857142857143	4.10279550957517	0.0153473402213388	0.0819006685516505
GO:0044183	protein folding chaperone	7/649	75/18639	0.0933333333333333	2.68049306625578	0.0154358244498676	0.0819006685516505
GO:0048156	tau protein binding	5/649	43/18639	0.116279069767442	3.33948471709607	0.0162796998446795	0.0858730366076074
GO:0004707	MAP kinase activity	3/649	16/18639	0.1875	5.38491910631741	0.0167724942139151	0.0859590328463151
GO:0022858	alanine transmembrane transporter activity	3/649	16/18639	0.1875	5.38491910631741	0.0167724942139151	0.0859590328463151
GO:0034450	ubiquitin-ubiquitin ligase activity	3/649	16/18639	0.1875	5.38491910631741	0.0167724942139151	0.0859590328463151
GO:0070411	I-SMAD binding	3/649	16/18639	0.1875	5.38491910631741	0.0167724942139151	0.0859590328463151
GO:0140328	floppase activity	3/649	16/18639	0.1875	5.38491910631741	0.0167724942139151	0.0859590328463151
GO:0019887	protein kinase regulator activity	16/649	255/18639	0.0627450980392157	1.80201214538204	0.0171853026974344	0.0875770792829709
GO:0106222	lncRNA binding	4/649	29/18639	0.137931034482759	3.96131980234844	0.0173245057628029	0.0877904730227428
GO:0008276	protein methyltransferase activity	8/649	95/18639	0.0842105263157895	2.41848998459168	0.0177323387187888	0.089355137007528
GO:0001046	core promoter sequence-specific DNA binding	5/649	44/18639	0.113636363636364	3.26358733716207	0.0178560230332644	0.0894785154222471
GO:0008187	poly-pyrimidine tract binding	4/649	30/18639	0.133333333333333	3.82927580893683	0.0194533727690024	0.0964117705364844
GO:0031624	ubiquitin conjugating enzyme binding	4/649	30/18639	0.133333333333333	3.82927580893683	0.0194533727690024	0.0964117705364844
GO:0015294	solute:monoatomic cation symporter activity	9/649	116/18639	0.0775862068965517	2.228242388821	0.0200627064062311	0.0988883124503849
GO:0008170	N-methyltransferase activity	8/649	98/18639	0.0816326530612245	2.3444545769001	0.0209936703958801	0.102914623353717
GO:0033192	calmodulin-dependent protein phosphatase activity	7/649	81/18639	0.0864197530864197	2.48193802431091	0.0226689029904993	0.106496617174117
GO:0140791	histone H2AXS140 phosphatase activity	7/649	81/18639	0.0864197530864197	2.48193802431091	0.0226689029904993	0.106496617174117
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	7/649	81/18639	0.0864197530864197	2.48193802431091	0.0226689029904993	0.106496617174117
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	7/649	81/18639	0.0864197530864197	2.48193802431091	0.0226689029904993	0.106496617174117
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	7/649	81/18639	0.0864197530864197	2.48193802431091	0.0226689029904993	0.106496617174117
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	7/649	81/18639	0.0864197530864197	2.48193802431091	0.0226689029904993	0.106496617174117
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	7/649	81/18639	0.0864197530864197	2.48193802431091	0.0226689029904993	0.106496617174117
GO:1990439	MAP kinase serine/threonine phosphatase activity	7/649	81/18639	0.0864197530864197	2.48193802431091	0.0226689029904993	0.106496617174117
GO:1990518	single-stranded 3'-5' DNA helicase activity	5/649	47/18639	0.106382978723404	3.0552732518113	0.0231787166708367	0.107941586873061
GO:0035615	clathrin adaptor activity	3/649	18/18639	0.166666666666667	4.78659476117103	0.0232158180192614	0.107941586873061
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	7/649	82/18639	0.0853658536585366	2.45167048742907	0.0240684087480798	0.110699841469133
GO:0033549	MAP kinase phosphatase activity	7/649	82/18639	0.0853658536585366	2.45167048742907	0.0240684087480798	0.110699841469133
GO:0043425	bHLH transcription factor binding	4/649	32/18639	0.125	3.58994607087827	0.0241772381035689	0.110699841469133
GO:0043138	3'-5' DNA helicase activity	5/649	48/18639	0.104166666666667	2.9916217257319	0.0251573684919029	0.114605789796446
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	7/649	83/18639	0.0843373493975904	2.42213228878534	0.0255261619175877	0.115122990248321
GO:0008135	translation factor activity, RNA binding	7/649	83/18639	0.0843373493975904	2.42213228878534	0.0255261619175877	0.115122990248321
GO:0030296	protein tyrosine kinase activator activity	4/649	33/18639	0.121212121212121	3.48115982630621	0.0267767941311651	0.11841219953391
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/649	19/18639	0.157894736842105	4.5346687211094	0.0268715336275885	0.11841219953391
GO:0022821	solute:potassium antiporter activity	3/649	19/18639	0.157894736842105	4.5346687211094	0.0268715336275885	0.11841219953391
GO:1990380	K48-linked deubiquitinase activity	3/649	19/18639	0.157894736842105	4.5346687211094	0.0268715336275885	0.11841219953391
GO:0017018	myosin phosphatase activity	7/649	84/18639	0.0833333333333333	2.39329738058552	0.0270431409135095	0.11841219953391
GO:0180051	translation factor activity	7/649	84/18639	0.0833333333333333	2.39329738058552	0.0270431409135095	0.11841219953391
GO:0060590	ATPase regulator activity	5/649	49/18639	0.102040816326531	2.93056822112512	0.0272411253967204	0.11870287491711
GO:0042277	peptide binding	15/649	249/18639	0.0602409638554217	1.73009449198953	0.0283462572674442	0.122924634880936
GO:0005516	calmodulin binding	13/649	207/18639	0.0628019323671498	1.8036444027601	0.0295716276532725	0.127624919345702
GO:0030742	GTP-dependent protein binding	3/649	20/18639	0.15	4.30793528505393	0.0308155811872567	0.131111576560875
GO:0042288	MHC class I protein binding	3/649	20/18639	0.15	4.30793528505393	0.0308155811872567	0.131111576560875
GO:0061608	nuclear import signal receptor activity	3/649	20/18639	0.15	4.30793528505393	0.0308155811872567	0.131111576560875
GO:0005080	protein kinase C binding	5/649	52/18639	0.0961538461538462	2.76149697759867	0.0341374264973057	0.143887657479298
GO:0030159	signaling receptor complex adaptor activity	5/649	52/18639	0.0961538461538462	2.76149697759867	0.0341374264973057	0.143887657479298
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	3/649	21/18639	0.142857142857143	4.10279550957517	0.0350458099732588	0.145006057779263
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	3/649	21/18639	0.142857142857143	4.10279550957517	0.0350458099732588	0.145006057779263
GO:0072542	protein phosphatase activator activity	3/649	21/18639	0.142857142857143	4.10279550957517	0.0350458099732588	0.145006057779263
GO:0140312	cargo adaptor activity	3/649	21/18639	0.142857142857143	4.10279550957517	0.0350458099732588	0.145006057779263
GO:0044390	ubiquitin-like protein conjugating enzyme binding	4/649	36/18639	0.111111111111111	3.19106317411402	0.0355454603366975	0.145086976765411
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	7/649	89/18639	0.0786516853932584	2.25884247156386	0.035547917810594	0.145086976765411
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	7/649	89/18639	0.0786516853932584	2.25884247156386	0.035547917810594	0.145086976765411
GO:0140296	general transcription initiation factor binding	5/649	53/18639	0.0943396226415094	2.70939326104021	0.0366552499765568	0.148059358125685
GO:0140793	histone H2AXY142 phosphatase activity	7/649	90/18639	0.0777777777777778	2.23374422187982	0.0374385677941947	0.148059358125685
GO:0003779	actin binding	23/649	443/18639	0.0519187358916479	1.4910836953535	0.0375993838707514	0.148059358125685
GO:0005518	collagen binding	6/649	72/18639	0.0833333333333333	2.39329738058552	0.0392219444178563	0.148059358125685
GO:0140463	chromatin-protein adaptor activity	5/649	54/18639	0.0925925925925926	2.65921931176168	0.039284246357232	0.148059358125685
GO:0008970	phospholipase A1 activity	3/649	22/18639	0.136363636363636	3.91630480459448	0.0395590967941131	0.148059358125685
GO:0015377	chloride:monoatomic cation symporter activity	3/649	22/18639	0.136363636363636	3.91630480459448	0.0395590967941131	0.148059358125685
GO:0032931	histone H3K56 acetyltransferase activity	3/649	22/18639	0.136363636363636	3.91630480459448	0.0395590967941131	0.148059358125685
GO:0043992	histone H3K9 acetyltransferase activity	3/649	22/18639	0.136363636363636	3.91630480459448	0.0395590967941131	0.148059358125685
GO:0043993	histone H3K18 acetyltransferase activity	3/649	22/18639	0.136363636363636	3.91630480459448	0.0395590967941131	0.148059358125685
GO:0043994	histone H3K23 acetyltransferase activity	3/649	22/18639	0.136363636363636	3.91630480459448	0.0395590967941131	0.148059358125685
GO:0043999	histone H2AK5 acetyltransferase activity	3/649	22/18639	0.136363636363636	3.91630480459448	0.0395590967941131	0.148059358125685
GO:0044012	histone H2AK9 acetyltransferase activity	3/649	22/18639	0.136363636363636	3.91630480459448	0.0395590967941131	0.148059358125685
GO:0044014	histone H2BK5 acetyltransferase activity	3/649	22/18639	0.136363636363636	3.91630480459448	0.0395590967941131	0.148059358125685
GO:0044015	histone H2BK12 acetyltransferase activity	3/649	22/18639	0.136363636363636	3.91630480459448	0.0395590967941131	0.148059358125685
GO:0044016	histone H3K4 acetyltransferase activity	3/649	22/18639	0.136363636363636	3.91630480459448	0.0395590967941131	0.148059358125685
GO:0044017	histone H3K27 acetyltransferase activity	3/649	22/18639	0.136363636363636	3.91630480459448	0.0395590967941131	0.148059358125685
GO:0044018	histone H3K36 acetyltransferase activity	3/649	22/18639	0.136363636363636	3.91630480459448	0.0395590967941131	0.148059358125685
GO:0046972	histone H4K16 acetyltransferase activity	3/649	22/18639	0.136363636363636	3.91630480459448	0.0395590967941131	0.148059358125685
GO:0140908	histone H3K122 acetyltransferase activity	3/649	22/18639	0.136363636363636	3.91630480459448	0.0395590967941131	0.148059358125685
GO:0140030	modification-dependent protein binding	11/649	173/18639	0.0635838150289017	1.82609973547565	0.039934324789163	0.148846119668698
GO:0043539	protein serine/threonine kinase activator activity	6/649	73/18639	0.0821917808219178	2.36051248496106	0.0415306930085549	0.154159197916529
GO:0005525	GTP binding	20/649	378/18639	0.0529100529100529	1.51955389243525	0.0425584091334151	0.155222775551746
GO:0003678	DNA helicase activity	6/649	74/18639	0.0810810810810811	2.32861366759672	0.0439233638080789	0.155222775551746
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	3/649	23/18639	0.130434782608696	3.74603068265559	0.0443514427791445	0.155222775551746
GO:0005283	amino acid:sodium symporter activity	3/649	23/18639	0.130434782608696	3.74603068265559	0.0443514427791445	0.155222775551746
GO:0044013	histone H2B acetyltransferase activity	3/649	23/18639	0.130434782608696	3.74603068265559	0.0443514427791445	0.155222775551746
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	3/649	23/18639	0.130434782608696	3.74603068265559	0.0443514427791445	0.155222775551746
GO:0070577	lysine-acetylated histone binding	3/649	23/18639	0.130434782608696	3.74603068265559	0.0443514427791445	0.155222775551746
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	3/649	23/18639	0.130434782608696	3.74603068265559	0.0443514427791445	0.155222775551746
GO:0001094	TFIID-class transcription factor complex binding	2/649	10/18639	0.2	5.74391371340524	0.0452589689247331	0.155222775551746
GO:0004445	inositol-polyphosphate 5-phosphatase activity	2/649	10/18639	0.2	5.74391371340524	0.0452589689247331	0.155222775551746
GO:0008140	cAMP response element binding protein binding	2/649	10/18639	0.2	5.74391371340524	0.0452589689247331	0.155222775551746
GO:0015643	toxic substance binding	2/649	10/18639	0.2	5.74391371340524	0.0452589689247331	0.155222775551746
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	2/649	10/18639	0.2	5.74391371340524	0.0452589689247331	0.155222775551746
GO:0031956	medium-chain fatty acid-CoA ligase activity	2/649	10/18639	0.2	5.74391371340524	0.0452589689247331	0.155222775551746
GO:0032395	MHC class II receptor activity	2/649	10/18639	0.2	5.74391371340524	0.0452589689247331	0.155222775551746
GO:0035256	G protein-coupled glutamate receptor binding	2/649	10/18639	0.2	5.74391371340524	0.0452589689247331	0.155222775551746
GO:0050815	phosphoserine residue binding	2/649	10/18639	0.2	5.74391371340524	0.0452589689247331	0.155222775551746
GO:0099122	RNA polymerase II C-terminal domain binding	2/649	10/18639	0.2	5.74391371340524	0.0452589689247331	0.155222775551746
GO:0140940	histone H2A methyltransferase activity	2/649	10/18639	0.2	5.74391371340524	0.0452589689247331	0.155222775551746
GO:1990259	histone H2AQ104 methyltransferase activity	2/649	10/18639	0.2	5.74391371340524	0.0452589689247331	0.155222775551746
GO:0016410	N-acyltransferase activity	7/649	94/18639	0.074468085106383	2.13869127626791	0.0456566825822258	0.155846373964574
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	4/649	39/18639	0.102564102564103	2.94559677610525	0.045786351552785	0.155846373964574
GO:0140789	histone phosphatase activity	9/649	136/18639	0.0661764705882353	1.90055968458262	0.0483782163890959	0.16404944053746
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	3/649	24/18639	0.125	3.58994607087827	0.0494180637070542	0.164242961689215
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	3/649	24/18639	0.125	3.58994607087827	0.0494180637070542	0.164242961689215
GO:0043998	histone H2A acetyltransferase activity	3/649	24/18639	0.125	3.58994607087827	0.0494180637070542	0.164242961689215
GO:0050699	WW domain binding	3/649	24/18639	0.125	3.58994607087827	0.0494180637070542	0.164242961689215
GO:0030331	nuclear estrogen receptor binding	4/649	40/18639	0.1	2.87195685670262	0.0495278110637101	0.164242961689215
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	4/649	40/18639	0.1	2.87195685670262	0.0495278110637101	0.164242961689215
GO:0015631	tubulin binding	20/649	385/18639	0.051948051948052	1.49192563984552	0.0497205342881423	0.164278102300016
GO:0004896	cytokine receptor activity	7/649	96/18639	0.0729166666666667	2.09413520801233	0.0501668543831796	0.165147819903752
GO:0017116	single-stranded DNA helicase activity	5/649	58/18639	0.0862068965517241	2.47582487646778	0.0509249129774513	0.16703371456604
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	11/649	181/18639	0.0607734806629834	1.74538814495739	0.052267942763774	0.170817697003348
GO:0015175	neutral L-amino acid transmembrane transporter activity	4/649	41/18639	0.0975609756097561	2.80190912849036	0.0534323606578701	0.171279314335935
GO:0042169	SH2 domain binding	4/649	41/18639	0.0975609756097561	2.80190912849036	0.0534323606578701	0.171279314335935
GO:0003953	NAD+ nucleosidase activity	2/649	11/18639	0.181818181818182	5.22173973945931	0.0540666996808816	0.171279314335935
GO:0015173	aromatic amino acid transmembrane transporter activity	2/649	11/18639	0.181818181818182	5.22173973945931	0.0540666996808816	0.171279314335935
GO:0034713	type I transforming growth factor beta receptor binding	2/649	11/18639	0.181818181818182	5.22173973945931	0.0540666996808816	0.171279314335935
GO:0070697	activin receptor binding	2/649	11/18639	0.181818181818182	5.22173973945931	0.0540666996808816	0.171279314335935
GO:0140031	phosphorylation-dependent protein binding	2/649	11/18639	0.181818181818182	5.22173973945931	0.0540666996808816	0.171279314335935
GO:0140537	transcription regulator activator activity	2/649	11/18639	0.181818181818182	5.22173973945931	0.0540666996808816	0.171279314335935
GO:0070888	E-box binding	5/649	59/18639	0.0847457627118644	2.43386174296832	0.0541181869021524	0.171279314335935
GO:0015296	monoatomic anion:monoatomic cation symporter activity	3/649	25/18639	0.12	3.44634822804314	0.0547534742383624	0.171484839454871
GO:0019211	phosphatase activator activity	3/649	25/18639	0.12	3.44634822804314	0.0547534742383624	0.171484839454871
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	3/649	25/18639	0.12	3.44634822804314	0.0547534742383624	0.171484839454871
GO:0004725	protein tyrosine phosphatase activity	7/649	98/18639	0.0714285714285714	2.05139775478759	0.0549492327730598	0.171502449693079
GO:0098531	ligand-modulated transcription factor activity	5/649	60/18639	0.0833333333333333	2.39329738058552	0.0574249675124791	0.178227324713012
GO:0019894	kinesin binding	4/649	42/18639	0.0952380952380952	2.73519700638345	0.0574990593032	0.178227324713012
GO:0030695	GTPase regulator activity	24/649	489/18639	0.049079754601227	1.40954937752276	0.0582696673974866	0.179997397234702
GO:0060589	nucleoside-triphosphatase regulator activity	24/649	490/18639	0.0489795918367347	1.40667274614006	0.0593550826740381	0.182674875466745
GO:0004112	cyclic-nucleotide phosphodiesterase activity	3/649	26/18639	0.115384615384615	3.31379637311841	0.0603515663958868	0.182674875466745
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	3/649	26/18639	0.115384615384615	3.31379637311841	0.0603515663958868	0.182674875466745
GO:0008143	poly(A) binding	3/649	26/18639	0.115384615384615	3.31379637311841	0.0603515663958868	0.182674875466745
GO:0008157	protein phosphatase 1 binding	3/649	26/18639	0.115384615384615	3.31379637311841	0.0603515663958868	0.182674875466745
GO:0034237	protein kinase A regulatory subunit binding	3/649	26/18639	0.115384615384615	3.31379637311841	0.0603515663958868	0.182674875466745
GO:0005527	macrolide binding	2/649	12/18639	0.166666666666667	4.78659476117103	0.0634186959981962	0.185726181137575
GO:0015368	calcium:monoatomic cation antiporter activity	2/649	12/18639	0.166666666666667	4.78659476117103	0.0634186959981962	0.185726181137575
GO:0035197	siRNA binding	2/649	12/18639	0.166666666666667	4.78659476117103	0.0634186959981962	0.185726181137575
GO:0036009	protein-glutamine N-methyltransferase activity	2/649	12/18639	0.166666666666667	4.78659476117103	0.0634186959981962	0.185726181137575
GO:0070410	co-SMAD binding	2/649	12/18639	0.166666666666667	4.78659476117103	0.0634186959981962	0.185726181137575
GO:0070679	inositol 1,4,5 trisphosphate binding	2/649	12/18639	0.166666666666667	4.78659476117103	0.0634186959981962	0.185726181137575
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	2/649	12/18639	0.166666666666667	4.78659476117103	0.0634186959981962	0.185726181137575
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	2/649	12/18639	0.166666666666667	4.78659476117103	0.0634186959981962	0.185726181137575
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	2/649	12/18639	0.166666666666667	4.78659476117103	0.0634186959981962	0.185726181137575
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	2/649	12/18639	0.166666666666667	4.78659476117103	0.0634186959981962	0.185726181137575
GO:0004683	calcium/calmodulin-dependent protein kinase activity	3/649	27/18639	0.111111111111111	3.19106317411402	0.066205682619875	0.192637179752023
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	3/649	27/18639	0.111111111111111	3.19106317411402	0.066205682619875	0.192637179752023
GO:0019001	guanyl nucleotide binding	20/649	400/18639	0.05	1.43597842835131	0.0678853360296184	0.196258247111269
GO:0032561	guanyl ribonucleotide binding	20/649	400/18639	0.05	1.43597842835131	0.0678853360296184	0.196258247111269
GO:0004722	protein serine/threonine phosphatase activity	7/649	103/18639	0.0679611650485437	1.95181533950663	0.0681113376662482	0.196282513019028
GO:0019789	SUMO transferase activity	3/649	28/18639	0.107142857142857	3.07709663218138	0.0723086837076993	0.206400103494762
GO:0051959	dynein light intermediate chain binding	3/649	28/18639	0.107142857142857	3.07709663218138	0.0723086837076993	0.206400103494762
GO:0097718	disordered domain specific binding	3/649	28/18639	0.107142857142857	3.07709663218138	0.0723086837076993	0.206400103494762
GO:0046975	histone H3K36 methyltransferase activity	2/649	13/18639	0.153846153846154	4.41839516415788	0.0732665059974826	0.207167361785985
GO:0140333	glycerophospholipid flippase activity	2/649	13/18639	0.153846153846154	4.41839516415788	0.0732665059974826	0.207167361785985
GO:0140852	histone ubiquitin ligase activity	2/649	13/18639	0.153846153846154	4.41839516415788	0.0732665059974826	0.207167361785985
GO:0008013	beta-catenin binding	7/649	106/18639	0.0660377358490566	1.89657528272814	0.0768413684843692	0.216596607415316
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	3/649	29/18639	0.103448275862069	2.97098985176133	0.0786530119321105	0.219644014745398
GO:0005416	amino acid:monoatomic cation symporter activity	3/649	29/18639	0.103448275862069	2.97098985176133	0.0786530119321105	0.219644014745398
GO:0097472	cyclin-dependent protein kinase activity	3/649	29/18639	0.103448275862069	2.97098985176133	0.0786530119321105	0.219644014745398
GO:0061749	forked DNA-dependent helicase activity	4/649	47/18639	0.0851063829787234	2.44421860144904	0.0802129719534135	0.223308952783886
GO:0004843	cysteine-type deubiquitinase activity	7/649	108/18639	0.0648148148148148	1.86145351823318	0.0830082814819318	0.228409313571446
GO:0008494	translation activator activity	2/649	14/18639	0.142857142857143	4.10279550957517	0.0835643830139435	0.228409313571446
GO:0008559	ABC-type xenobiotic transporter activity	2/649	14/18639	0.142857142857143	4.10279550957517	0.0835643830139435	0.228409313571446
GO:0032454	histone H3K9 demethylase activity	2/649	14/18639	0.142857142857143	4.10279550957517	0.0835643830139435	0.228409313571446
GO:0046030	inositol trisphosphate phosphatase activity	2/649	14/18639	0.142857142857143	4.10279550957517	0.0835643830139435	0.228409313571446
GO:0061665	SUMO ligase activity	2/649	14/18639	0.142857142857143	4.10279550957517	0.0835643830139435	0.228409313571446
GO:0140098	catalytic activity, acting on RNA	19/649	387/18639	0.0490956072351421	1.41000465832945	0.0844623039050461	0.228803976650131
GO:0042578	phosphoric ester hydrolase activity	18/649	363/18639	0.0495867768595041	1.42411083803436	0.0849700471086516	0.228803976650131
GO:0009378	four-way junction helicase activity	4/649	48/18639	0.0833333333333333	2.39329738058552	0.0852180268135508	0.228803976650131
GO:0036121	double-stranded DNA helicase activity	4/649	48/18639	0.0833333333333333	2.39329738058552	0.0852180268135508	0.228803976650131
GO:0001965	G-protein alpha-subunit binding	3/649	30/18639	0.1	2.87195685670262	0.0852307496169003	0.228803976650131
GO:0070566	adenylyltransferase activity	3/649	30/18639	0.1	2.87195685670262	0.0852307496169003	0.228803976650131
GO:0005548	phospholipid transporter activity	5/649	68/18639	0.0735294117647059	2.11173298286957	0.0879230409945137	0.235331106756829
GO:0043021	ribonucleoprotein complex binding	10/649	177/18639	0.0564971751412429	1.62257449531221	0.090851534739848	0.242449953654861
GO:0005164	tumor necrosis factor receptor binding	3/649	31/18639	0.0967741935483871	2.77931308713157	0.092033673434401	0.244880157633716
GO:0042809	nuclear vitamin D receptor binding	2/649	15/18639	0.133333333333333	3.82927580893683	0.0942691564244839	0.25009052674966
GO:0140375	immune receptor activity	9/649	156/18639	0.0576923076923077	1.6568981865592	0.0953074097802592	0.251547414218643
GO:0046982	protein heterodimerization activity	18/649	369/18639	0.0487804878048781	1.40095456424518	0.0953760705795743	0.251547414218643
GO:0051087	protein-folding chaperone binding	8/649	134/18639	0.0597014925373134	1.71460110847918	0.0963783143264588	0.253070335806317
GO:0097110	scaffold protein binding	5/649	70/18639	0.0714285714285714	2.05139775478759	0.0966437276575535	0.253070335806317
GO:0016791	phosphatase activity	14/649	273/18639	0.0512820512820513	1.47279838805263	0.0967951949591791	0.253070335806317
GO:0030515	snoRNA binding	3/649	32/18639	0.09375	2.69245955315871	0.0990533046755215	0.256741611544024
GO:0070717	poly-purine tract binding	3/649	32/18639	0.09375	2.69245955315871	0.0990533046755215	0.256741611544024
GO:0140142	nucleocytoplasmic carrier activity	3/649	32/18639	0.09375	2.69245955315871	0.0990533046755215	0.256741611544024
GO:0003743	translation initiation factor activity	4/649	51/18639	0.0784313725490196	2.25251518172754	0.101112431876682	0.261327832529419
GO:0002020	protease binding	8/649	136/18639	0.0588235294117647	1.68938638629566	0.102713746760993	0.264707998795472
GO:0003688	DNA replication origin binding	2/649	16/18639	0.125	3.58994607087827	0.105340108168851	0.266153438566677
GO:0004708	MAP kinase kinase activity	2/649	16/18639	0.125	3.58994607087827	0.105340108168851	0.266153438566677
GO:0015378	sodium:chloride symporter activity	2/649	16/18639	0.125	3.58994607087827	0.105340108168851	0.266153438566677
GO:0015562	efflux transmembrane transporter activity	2/649	16/18639	0.125	3.58994607087827	0.105340108168851	0.266153438566677
GO:0031435	mitogen-activated protein kinase kinase kinase binding	2/649	16/18639	0.125	3.58994607087827	0.105340108168851	0.266153438566677
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/649	16/18639	0.125	3.58994607087827	0.105340108168851	0.266153438566677
GO:0140327	flippase activity	2/649	16/18639	0.125	3.58994607087827	0.105340108168851	0.266153438566677
GO:0101005	deubiquitinase activity	7/649	115/18639	0.0608695652173913	1.74814765190594	0.106751405937507	0.26896583283696
GO:0005085	guanyl-nucleotide exchange factor activity	12/649	230/18639	0.0521739130434783	1.49841227306224	0.107339028327192	0.269693046103418
GO:0004864	protein phosphatase inhibitor activity	4/649	53/18639	0.0754716981132075	2.16751460883217	0.112411105373813	0.281652269575498
GO:0030332	cyclin binding	3/649	34/18639	0.0882352941176471	2.53407957944349	0.113707773001775	0.283823307176637
GO:0051015	actin filament binding	11/649	209/18639	0.0526315789473684	1.5115562403698	0.114296972336018	0.283823307176637
GO:0004713	protein tyrosine kinase activity	8/649	140/18639	0.0571428571428571	1.64111820383007	0.116062340365385	0.283823307176637
GO:0005092	GDP-dissociation inhibitor activity	2/649	17/18639	0.117647058823529	3.37877277259132	0.116738854725646	0.283823307176637
GO:0015278	intracellularly gated calcium channel activity	2/649	17/18639	0.117647058823529	3.37877277259132	0.116738854725646	0.283823307176637
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/649	17/18639	0.117647058823529	3.37877277259132	0.116738854725646	0.283823307176637
GO:0032977	membrane insertase activity	2/649	17/18639	0.117647058823529	3.37877277259132	0.116738854725646	0.283823307176637
GO:0036041	long-chain fatty acid binding	2/649	17/18639	0.117647058823529	3.37877277259132	0.116738854725646	0.283823307176637
GO:0038191	neuropilin binding	2/649	17/18639	0.117647058823529	3.37877277259132	0.116738854725646	0.283823307176637
GO:0046965	nuclear retinoid X receptor binding	2/649	17/18639	0.117647058823529	3.37877277259132	0.116738854725646	0.283823307176637
GO:1990226	histone methyltransferase binding	2/649	17/18639	0.117647058823529	3.37877277259132	0.116738854725646	0.283823307176637
GO:0000175	3'-5'-RNA exonuclease activity	3/649	35/18639	0.0857142857142857	2.4616773057451	0.121324776473752	0.29260681384846
GO:0005343	organic acid:sodium symporter activity	3/649	35/18639	0.0857142857142857	2.4616773057451	0.121324776473752	0.29260681384846
GO:0140566	histone reader activity	3/649	35/18639	0.0857142857142857	2.4616773057451	0.121324776473752	0.29260681384846
GO:0008525	phosphatidylcholine transporter activity	2/649	18/18639	0.111111111111111	3.19106317411402	0.128429234313944	0.307853909588751
GO:0015373	monoatomic anion:sodium symporter activity	2/649	18/18639	0.111111111111111	3.19106317411402	0.128429234313944	0.307853909588751
GO:0005484	SNAP receptor activity	3/649	36/18639	0.0833333333333333	2.39329738058552	0.129122896122575	0.307853909588751
GO:0015291	secondary active transmembrane transporter activity	14/649	287/18639	0.0487804878048781	1.40095456424518	0.129433887459525	0.307853909588751
GO:0003697	single-stranded DNA binding	7/649	121/18639	0.0578512396694215	1.66146264437342	0.129694551711447	0.307853909588751
GO:0051082	unfolded protein binding	7/649	121/18639	0.0578512396694215	1.66146264437342	0.129694551711447	0.307853909588751
GO:0019212	phosphatase inhibitor activity	4/649	56/18639	0.0714285714285714	2.05139775478759	0.130345316446294	0.308586549697
GO:0005520	insulin-like growth factor binding	2/649	19/18639	0.105263157894737	3.0231124807396	0.140377199100574	0.327184066120717
GO:0031420	alkali metal ion binding	2/649	19/18639	0.105263157894737	3.0231124807396	0.140377199100574	0.327184066120717
GO:0034987	immunoglobulin receptor binding	2/649	19/18639	0.105263157894737	3.0231124807396	0.140377199100574	0.327184066120717
GO:0042800	histone H3K4 methyltransferase activity	2/649	19/18639	0.105263157894737	3.0231124807396	0.140377199100574	0.327184066120717
GO:0046624	sphingolipid transporter activity	2/649	19/18639	0.105263157894737	3.0231124807396	0.140377199100574	0.327184066120717
GO:0140036	ubiquitin-modified protein reader activity	2/649	19/18639	0.105263157894737	3.0231124807396	0.140377199100574	0.327184066120717
GO:0015370	solute:sodium symporter activity	5/649	79/18639	0.0632911392405063	1.81769421310292	0.140904170799207	0.327565881600218
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	3/649	38/18639	0.0789473684210526	2.2673343605547	0.145225951795518	0.335881560306557
GO:0042162	telomeric DNA binding	3/649	38/18639	0.0789473684210526	2.2673343605547	0.145225951795518	0.335881560306557
GO:0004879	nuclear receptor activity	4/649	59/18639	0.0677966101694915	1.94708939437466	0.149373975646136	0.344591626682391
GO:0015101	organic cation transmembrane transporter activity	5/649	81/18639	0.0617283950617284	1.77281287450779	0.151769002680982	0.349223572495526
GO:0052745	inositol phosphate phosphatase activity	2/649	20/18639	0.1	2.87195685670262	0.152550712202053	0.350129115537537
GO:0019783	ubiquitin-like protein peptidase activity	7/649	127/18639	0.0551181102362205	1.58296834621404	0.154885235413373	0.354584980565641
GO:0004721	phosphoprotein phosphatase activity	9/649	175/18639	0.0514285714285714	1.47700638344706	0.157952277525491	0.360691023615173
GO:0004532	RNA exonuclease activity	3/649	40/18639	0.075	2.15396764252696	0.161943783047893	0.366098476965411
GO:0061791	GTPase motor activity	3/649	40/18639	0.075	2.15396764252696	0.161943783047893	0.366098476965411
GO:0140662	ATP-dependent protein folding chaperone	3/649	40/18639	0.075	2.15396764252696	0.161943783047893	0.366098476965411
GO:1990606	membrane scission GTPase motor activity	3/649	40/18639	0.075	2.15396764252696	0.161943783047893	0.366098476965411
GO:0035613	RNA stem-loop binding	2/649	21/18639	0.0952380952380952	2.73519700638345	0.164919649278769	0.371893809123623
GO:0051117	ATPase binding	5/649	84/18639	0.0595238095238095	1.70949812898965	0.168694657198699	0.379457807464405
GO:0015179	L-amino acid transmembrane transporter activity	4/649	62/18639	0.0645161290322581	1.85287539142104	0.169390158910488	0.380074436162338
GO:0042287	MHC protein binding	3/649	41/18639	0.0731707317073171	2.10143184636777	0.17051047428921	0.380694177744721
GO:0140828	metal cation:monoatomic cation antiporter activity	3/649	41/18639	0.0731707317073171	2.10143184636777	0.17051047428921	0.380694177744721
GO:0031072	heat shock protein binding	7/649	131/18639	0.0534351145038168	1.53463343487926	0.172837012534773	0.384935766188556
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	11/649	229/18639	0.0480349344978166	1.37954259492266	0.17667227961272	0.390402549959915
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	2/649	22/18639	0.0909090909090909	2.61086986972965	0.177455704527234	0.390402549959915
GO:0061133	endopeptidase activator activity	2/649	22/18639	0.0909090909090909	2.61086986972965	0.177455704527234	0.390402549959915
GO:0070034	telomerase RNA binding	2/649	22/18639	0.0909090909090909	2.61086986972965	0.177455704527234	0.390402549959915
GO:0140035	ubiquitin-like protein reader activity	2/649	22/18639	0.0909090909090909	2.61086986972965	0.177455704527234	0.390402549959915
GO:0031492	nucleosomal DNA binding	3/649	42/18639	0.0714285714285714	2.05139775478759	0.179203660057365	0.393288811123462
GO:0000287	magnesium ion binding	11/649	230/18639	0.0478260869565217	1.37354458364038	0.180154771686422	0.394416514711535
GO:0004712	protein serine/threonine/tyrosine kinase activity	3/649	43/18639	0.0697674418604651	2.00369083025764	0.188014433118092	0.410627163855979
GO:0005158	insulin receptor binding	2/649	23/18639	0.0869565217391304	2.49735378843706	0.190132300884195	0.412582230723872
GO:0043274	phospholipase binding	2/649	23/18639	0.0869565217391304	2.49735378843706	0.190132300884195	0.412582230723872
GO:0019843	rRNA binding	4/649	65/18639	0.0615384615384615	1.76735806566315	0.190281827030079	0.412582230723872
GO:0043022	ribosome binding	6/649	112/18639	0.0535714285714286	1.53854831609069	0.195875307205421	0.423691911509088
GO:0044325	transmembrane transporter binding	7/649	136/18639	0.0514705882352941	1.4782130880087	0.196465466773823	0.42394860050824
GO:0043014	alpha-tubulin binding	3/649	44/18639	0.0681818181818182	1.95815240229724	0.196933995136311	0.42394860050824
GO:0001091	RNA polymerase II general transcription initiation factor binding	2/649	24/18639	0.0833333333333333	2.39329738058552	0.202924504263935	0.431693167089786
GO:0015295	solute:proton symporter activity	2/649	24/18639	0.0833333333333333	2.39329738058552	0.202924504263935	0.431693167089786
GO:0035035	histone acetyltransferase binding	2/649	24/18639	0.0833333333333333	2.39329738058552	0.202924504263935	0.431693167089786
GO:0070300	phosphatidic acid binding	2/649	24/18639	0.0833333333333333	2.39329738058552	0.202924504263935	0.431693167089786
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/649	24/18639	0.0833333333333333	2.39329738058552	0.202924504263935	0.431693167089786
GO:0003730	mRNA 3'-UTR binding	12/649	262/18639	0.0458015267175573	1.31540008703937	0.204347309138672	0.432282532393897
GO:0019210	kinase inhibitor activity	5/649	90/18639	0.0555555555555556	1.59553158705701	0.204573800657511	0.432282532393897
GO:0050840	extracellular matrix binding	4/649	67/18639	0.0597014925373134	1.71460110847918	0.204639291942566	0.432282532393897
GO:0140303	intramembrane lipid transporter activity	3/649	45/18639	0.0666666666666667	1.91463790446841	0.205953672240064	0.434042552244248
GO:0046943	carboxylic acid transmembrane transporter activity	9/649	188/18639	0.0478723404255319	1.37487296331508	0.209883197170684	0.440406482748941
GO:0030145	manganese ion binding	4/649	68/18639	0.0588235294117647	1.68938638629566	0.211934057626819	0.440406482748941
GO:0017124	SH3 domain binding	6/649	115/18639	0.0521739130434783	1.49841227306224	0.212226213097219	0.440406482748941
GO:0035401	histone H3Y41 kinase activity	6/649	115/18639	0.0521739130434783	1.49841227306224	0.212226213097219	0.440406482748941
GO:0140801	histone H2AXY142 kinase activity	6/649	115/18639	0.0521739130434783	1.49841227306224	0.212226213097219	0.440406482748941
GO:0015081	sodium ion transmembrane transporter activity	8/649	164/18639	0.0487804878048781	1.40095456424518	0.213421651474283	0.440406482748941
GO:0005342	organic acid transmembrane transporter activity	9/649	189/18639	0.0476190476190476	1.36759850319172	0.214139880080737	0.440406482748941
GO:0030276	clathrin binding	3/649	46/18639	0.0652173913043478	1.8730153413278	0.215064928946551	0.440406482748941
GO:0015645	fatty acid ligase activity	2/649	25/18639	0.08	2.2975654853621	0.215808941657463	0.440406482748941
GO:0015662	P-type ion transporter activity	2/649	25/18639	0.08	2.2975654853621	0.215808941657463	0.440406482748941
GO:0017025	TBP-class protein binding	2/649	25/18639	0.08	2.2975654853621	0.215808941657463	0.440406482748941
GO:0017056	structural constituent of nuclear pore	2/649	25/18639	0.08	2.2975654853621	0.215808941657463	0.440406482748941
GO:0120515	fatty acid-CoA ligase activity	2/649	25/18639	0.08	2.2975654853621	0.215808941657463	0.440406482748941
GO:0140358	P-type transmembrane transporter activity	2/649	25/18639	0.08	2.2975654853621	0.215808941657463	0.440406482748941
GO:0043178	alcohol binding	5/649	92/18639	0.0543478260869565	1.56084611777316	0.217061407232614	0.44196250411697
GO:0005504	fatty acid binding	3/649	47/18639	0.0638297872340425	1.83316395108678	0.224259380559719	0.454566205089588
GO:0140359	ABC-type transporter activity	3/649	47/18639	0.0638297872340425	1.83316395108678	0.224259380559719	0.454566205089588
GO:0016782	transferase activity, transferring sulphur-containing groups	4/649	70/18639	0.0571428571428571	1.64111820383007	0.226734193565834	0.458552113444803
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	8/649	167/18639	0.0479041916167665	1.37578771578569	0.227375774723638	0.458820914543001
GO:0005096	GTPase activator activity	12/649	271/18639	0.044280442804428	1.27171521330005	0.23701398063804	0.477202255659625
GO:0016405	CoA-ligase activity	2/649	27/18639	0.0740740740740741	2.12737544940935	0.241768366154012	0.485690570759285
GO:0016763	pentosyltransferase activity	3/649	49/18639	0.0612244897959184	1.75834093267507	0.242865148163302	0.485730296326605
GO:0035254	glutamate receptor binding	3/649	49/18639	0.0612244897959184	1.75834093267507	0.242865148163302	0.485730296326605
GO:0022804	active transmembrane transporter activity	19/649	457/18639	0.0415754923413567	1.19403020300547	0.245161693679045	0.489238601102873
GO:0032813	tumor necrosis factor receptor superfamily binding	3/649	50/18639	0.06	1.72317411402157	0.252260540902585	0.501489293066781
GO:0015085	calcium ion transmembrane transporter activity	7/649	147/18639	0.0476190476190476	1.36759850319172	0.25241257101144	0.501489293066781
GO:0046875	ephrin receptor binding	2/649	28/18639	0.0714285714285714	2.05139775478759	0.25480372634219	0.504019651668104
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	2/649	28/18639	0.0714285714285714	2.05139775478759	0.25480372634219	0.504019651668104
GO:0042626	ATPase-coupled transmembrane transporter activity	5/649	98/18639	0.0510204081632653	1.46528411056256	0.255818797923796	0.504146662466562
GO:0008017	microtubule binding	12/649	276/18639	0.0434782608695652	1.24867689421853	0.255985777616059	0.504146662466562
GO:0031491	nucleosome binding	4/649	74/18639	0.0540540540540541	1.55240911173115	0.257057649494838	0.50515468375674
GO:0003823	antigen binding	8/649	174/18639	0.0459770114942529	1.32043993411615	0.261124378069775	0.512030845693342
GO:0030544	Hsp70 protein binding	3/649	51/18639	0.0588235294117647	1.68938638629566	0.261707297716704	0.512060699653942
GO:0019003	GDP binding	4/649	75/18639	0.0533333333333333	1.53171032357473	0.264764649653888	0.516921458848066
GO:0003785	actin monomer binding	2/649	29/18639	0.0689655172413793	1.98065990117422	0.267851927409603	0.519575136609596
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	2/649	29/18639	0.0689655172413793	1.98065990117422	0.267851927409603	0.519575136609596
GO:0099604	ligand-gated calcium channel activity	2/649	29/18639	0.0689655172413793	1.98065990117422	0.267851927409603	0.519575136609596
GO:0051018	protein kinase A binding	3/649	53/18639	0.0566037735849057	1.62563595662412	0.280725136541884	0.536290453506356
GO:0001968	fibronectin binding	2/649	30/18639	0.0666666666666667	1.91463790446841	0.280896297251939	0.536290453506356
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	2/649	30/18639	0.0666666666666667	1.91463790446841	0.280896297251939	0.536290453506356
GO:0031210	phosphatidylcholine binding	2/649	30/18639	0.0666666666666667	1.91463790446841	0.280896297251939	0.536290453506356
GO:0033612	receptor serine/threonine kinase binding	2/649	30/18639	0.0666666666666667	1.91463790446841	0.280896297251939	0.536290453506356
GO:0015171	amino acid transmembrane transporter activity	5/649	102/18639	0.0490196078431373	1.40782198857972	0.282526543580551	0.536290453506356
GO:0003774	cytoskeletal motor activity	7/649	153/18639	0.0457516339869281	1.31396718934107	0.284751137133975	0.536290453506356
GO:0003925	G protein activity	3/649	54/18639	0.0555555555555556	1.59553158705701	0.29028183550934	0.536290453506356
GO:0017069	snRNA binding	3/649	54/18639	0.0555555555555556	1.59553158705701	0.29028183550934	0.536290453506356
GO:0016878	acid-thiol ligase activity	2/649	31/18639	0.0645161290322581	1.85287539142104	0.293921305791079	0.536290453506356
GO:0047499	calcium-independent phospholipase A2 activity	2/649	31/18639	0.0645161290322581	1.85287539142104	0.293921305791079	0.536290453506356
GO:0000182	rDNA binding	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:0005528	FK506 binding	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:0008519	ammonium channel activity	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:0015187	glycine transmembrane transporter activity	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:0015279	store-operated calcium channel activity	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:0015924	mannosyl-oligosaccharide mannosidase activity	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:0030957	Tat protein binding	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:0031434	mitogen-activated protein kinase kinase binding	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:0042975	peroxisome proliferator activated receptor binding	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:0043422	protein kinase B binding	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:0045322	unmethylated CpG binding	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:0047429	nucleoside triphosphate diphosphatase activity	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:0070513	death domain binding	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:0098505	G-rich strand telomeric DNA binding	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:0140999	histone H3K4 trimethyltransferase activity	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	1/649	10/18639	0.1	2.87195685670262	0.298467635986908	0.536290453506356
GO:0016798	hydrolase activity, acting on glycosyl bonds	6/649	130/18639	0.0461538461538462	1.32551854924736	0.299827881877815	0.537663517800773
GO:0042910	xenobiotic transmembrane transporter activity	2/649	32/18639	0.0625	1.79497303543914	0.30691250586545	0.54818827780324
GO:0047498	calcium-dependent phospholipase A2 activity	2/649	32/18639	0.0625	1.79497303543914	0.30691250586545	0.54818827780324
GO:0170055	lipid transmembrane transporter activity	3/649	56/18639	0.0535714285714286	1.53854831609069	0.309456375496777	0.551049270954665
GO:0000149	SNARE binding	5/649	106/18639	0.0471698113207547	1.3546966305201	0.309736120148576	0.551049270954665
GO:0140272	exogenous protein binding	4/649	82/18639	0.0487804878048781	1.40095456424518	0.319671804106502	0.560120715605759
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/649	11/18639	0.0909090909090909	2.61086986972965	0.322907729617511	0.560120715605759
GO:0005114	type II transforming growth factor beta receptor binding	1/649	11/18639	0.0909090909090909	2.61086986972965	0.322907729617511	0.560120715605759
GO:0008526	phosphatidylinositol transfer activity	1/649	11/18639	0.0909090909090909	2.61086986972965	0.322907729617511	0.560120715605759
GO:0010854	adenylate cyclase regulator activity	1/649	11/18639	0.0909090909090909	2.61086986972965	0.322907729617511	0.560120715605759
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/649	11/18639	0.0909090909090909	2.61086986972965	0.322907729617511	0.560120715605759
GO:0019206	nucleoside kinase activity	1/649	11/18639	0.0909090909090909	2.61086986972965	0.322907729617511	0.560120715605759
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	1/649	11/18639	0.0909090909090909	2.61086986972965	0.322907729617511	0.560120715605759
GO:0032794	GTPase activating protein binding	1/649	11/18639	0.0909090909090909	2.61086986972965	0.322907729617511	0.560120715605759
GO:0047676	arachidonate-CoA ligase activity	1/649	11/18639	0.0909090909090909	2.61086986972965	0.322907729617511	0.560120715605759
GO:0070990	snRNP binding	1/649	11/18639	0.0909090909090909	2.61086986972965	0.322907729617511	0.560120715605759
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	1/649	11/18639	0.0909090909090909	2.61086986972965	0.322907729617511	0.560120715605759
GO:0180030	inositol phosphate kinase activity	1/649	11/18639	0.0909090909090909	2.61086986972965	0.322907729617511	0.560120715605759
GO:0008234	cysteine-type peptidase activity	8/649	187/18639	0.0427807486631016	1.22864464457866	0.327196654760292	0.566470983865227
GO:0008408	3'-5' exonuclease activity	3/649	58/18639	0.0517241379310345	1.48549492588067	0.32866899281813	0.567929945444356
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	2/649	34/18639	0.0588235294117647	1.68938638629566	0.332740770831944	0.572771326890102
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2/649	34/18639	0.0588235294117647	1.68938638629566	0.332740770831944	0.572771326890102
GO:0004860	protein kinase inhibitor activity	4/649	84/18639	0.0476190476190476	1.36759850319172	0.335551534985805	0.575581717995909
GO:0008514	organic anion transmembrane transporter activity	11/649	269/18639	0.0408921933085502	1.174406149581	0.336229274253416	0.575581717995909
GO:0031593	polyubiquitin modification-dependent protein binding	3/649	59/18639	0.0508474576271186	1.46031704578099	0.338274083023773	0.575581717995909
GO:0004623	phospholipase A2 activity	2/649	35/18639	0.0571428571428571	1.64111820383007	0.345553861399106	0.575581717995909
GO:0034061	DNA polymerase activity	2/649	35/18639	0.0571428571428571	1.64111820383007	0.345553861399106	0.575581717995909
GO:0000340	RNA 7-methylguanosine cap binding	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.575581717995909
GO:0003720	telomerase activity	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.575581717995909
GO:0005095	GTPase inhibitor activity	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.575581717995909
GO:0005436	sodium:phosphate symporter activity	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.575581717995909
GO:0008504	monoamine transmembrane transporter activity	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.575581717995909
GO:0015132	prostaglandin transmembrane transporter activity	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.575581717995909
GO:0016273	arginine N-methyltransferase activity	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.575581717995909
GO:0016274	protein-arginine N-methyltransferase activity	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.575581717995909
GO:0043047	single-stranded telomeric DNA binding	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.575581717995909
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.575581717995909
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.575581717995909
GO:0097677	STAT family protein binding	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.575581717995909
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.575581717995909
GO:0141221	histone deacetylase activity, hydrolytic mechanism	1/649	12/18639	0.0833333333333333	2.39329738058552	0.346497641764721	0.575581717995909
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	3/649	60/18639	0.05	1.43597842835131	0.347870520975477	0.576800018235074
GO:0005200	structural constituent of cytoskeleton	5/649	112/18639	0.0446428571428571	1.28212359674224	0.351139658129765	0.581152241528529
GO:0140767	enzyme-substrate adaptor activity	6/649	139/18639	0.0431654676258993	1.23969360720976	0.355321606687539	0.586996500425201
GO:0004869	cysteine-type endopeptidase inhibitor activity	2/649	36/18639	0.0555555555555556	1.59553158705701	0.358285094650668	0.588478350842666
GO:0045505	dynein intermediate chain binding	2/649	36/18639	0.0555555555555556	1.59553158705701	0.358285094650668	0.588478350842666
GO:0008081	phosphoric diester hydrolase activity	4/649	87/18639	0.0459770114942529	1.32043993411615	0.359421511448785	0.588478350842666
GO:0003964	RNA-directed DNA polymerase activity	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.588478350842666
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.588478350842666
GO:0005172	vascular endothelial growth factor receptor binding	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.588478350842666
GO:0008035	high-density lipoprotein particle binding	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.588478350842666
GO:0008253	5'-nucleotidase activity	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.588478350842666
GO:0009982	pseudouridine synthase activity	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.588478350842666
GO:0019104	DNA N-glycosylase activity	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.588478350842666
GO:0019855	calcium channel inhibitor activity	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.588478350842666
GO:0030955	potassium ion binding	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.588478350842666
GO:0031994	insulin-like growth factor I binding	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.588478350842666
GO:0035673	oligopeptide transmembrane transporter activity	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.588478350842666
GO:0046974	histone H3K9 methyltransferase activity	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.588478350842666
GO:0061459	L-arginine transmembrane transporter activity	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.588478350842666
GO:0071714	icosanoid transmembrane transporter activity	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.588478350842666
GO:0097157	pre-mRNA intronic binding	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.588478350842666
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.588478350842666
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/649	13/18639	0.0769230769230769	2.20919758207894	0.369266903078657	0.588478350842666
GO:0005543	phospholipid binding	19/649	497/18639	0.0382293762575453	1.09793119270321	0.370932185448318	0.590089649513903
GO:0004857	enzyme inhibitor activity	16/649	416/18639	0.0384615384615385	1.10459879103947	0.377709041410522	0.599154679195339
GO:0000146	microfilament motor activity	2/649	38/18639	0.0526315789473684	1.5115562403698	0.383463458765517	0.599154679195339
GO:0043531	ADP binding	2/649	38/18639	0.0526315789473684	1.5115562403698	0.383463458765517	0.599154679195339
GO:0061134	peptidase regulator activity	9/649	226/18639	0.0398230088495575	1.14369963320016	0.388714813894291	0.599154679195339
GO:0005161	platelet-derived growth factor receptor binding	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.599154679195339
GO:0008191	metalloendopeptidase inhibitor activity	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.599154679195339
GO:0008195	phosphatidate phosphatase activity	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.599154679195339
GO:0008474	palmitoyl-(protein) hydrolase activity	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.599154679195339
GO:0015386	potassium:proton antiporter activity	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.599154679195339
GO:0019992	diacylglycerol binding	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.599154679195339
GO:0030983	mismatched DNA binding	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.599154679195339
GO:0031404	chloride ion binding	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.599154679195339
GO:0034236	protein kinase A catalytic subunit binding	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.599154679195339
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.599154679195339
GO:0042043	neurexin family protein binding	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.599154679195339
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.599154679195339
GO:0070742	C2H2 zinc finger domain binding	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.599154679195339
GO:0071933	Arp2/3 complex binding	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.599154679195339
GO:0098599	palmitoyl hydrolase activity	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.599154679195339
GO:0098847	sequence-specific single stranded DNA binding	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.599154679195339
GO:1901474	azole transmembrane transporter activity	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.599154679195339
GO:1990825	sequence-specific mRNA binding	1/649	14/18639	0.0714285714285714	2.05139775478759	0.391244020006712	0.599154679195339
GO:0120013	lipid transfer activity	3/649	65/18639	0.0461538461538462	1.32551854924736	0.395533793448932	0.603202193610501
GO:0000217	DNA secondary structure binding	2/649	39/18639	0.0512820512820513	1.47279838805263	0.395893235717756	0.603202193610501
GO:0016776	phosphotransferase activity, phosphate group as acceptor	2/649	39/18639	0.0512820512820513	1.47279838805263	0.395893235717756	0.603202193610501
GO:0050997	quaternary ammonium group binding	2/649	40/18639	0.05	1.43597842835131	0.408206364805644	0.615953265325914
GO:0000774	adenyl-nucleotide exchange factor activity	1/649	15/18639	0.0666666666666667	1.91463790446841	0.412456510262586	0.615953265325914
GO:0004467	long-chain fatty acid-CoA ligase activity	1/649	15/18639	0.0666666666666667	1.91463790446841	0.412456510262586	0.615953265325914
GO:0004559	alpha-mannosidase activity	1/649	15/18639	0.0666666666666667	1.91463790446841	0.412456510262586	0.615953265325914
GO:0008252	nucleotidase activity	1/649	15/18639	0.0666666666666667	1.91463790446841	0.412456510262586	0.615953265325914
GO:0015556	C4-dicarboxylate transmembrane transporter activity	1/649	15/18639	0.0666666666666667	1.91463790446841	0.412456510262586	0.615953265325914
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/649	15/18639	0.0666666666666667	1.91463790446841	0.412456510262586	0.615953265325914
GO:0047372	monoacylglycerol lipase activity	1/649	15/18639	0.0666666666666667	1.91463790446841	0.412456510262586	0.615953265325914
GO:0050700	CARD domain binding	1/649	15/18639	0.0666666666666667	1.91463790446841	0.412456510262586	0.615953265325914
GO:0140161	monocarboxylate:sodium symporter activity	1/649	15/18639	0.0666666666666667	1.91463790446841	0.412456510262586	0.615953265325914
GO:0141050	histone H3K deacetylase activity	1/649	15/18639	0.0666666666666667	1.91463790446841	0.412456510262586	0.615953265325914
GO:0141051	histone H4K deacetylase activity	1/649	15/18639	0.0666666666666667	1.91463790446841	0.412456510262586	0.615953265325914
GO:0008168	methyltransferase activity	8/649	204/18639	0.0392156862745098	1.12625759086377	0.416970052159867	0.621664441401984
GO:0001530	lipopolysaccharide binding	2/649	41/18639	0.0487804878048781	1.40095456424518	0.420395897652641	0.623679440267569
GO:0001727	lipid kinase activity	2/649	41/18639	0.0487804878048781	1.40095456424518	0.420395897652641	0.623679440267569
GO:0016877	ligase activity, forming carbon-sulfur bonds	2/649	41/18639	0.0487804878048781	1.40095456424518	0.420395897652641	0.623679440267569
GO:0032934	sterol binding	3/649	68/18639	0.0441176470588235	1.26703978972174	0.423700810106047	0.627550296741633
GO:0005319	lipid transporter activity	7/649	178/18639	0.0393258426966292	1.12942123578193	0.426121695285549	0.628830443214314
GO:0048487	beta-tubulin binding	2/649	42/18639	0.0476190476190476	1.36759850319172	0.432455509532405	0.628830443214314
GO:0051879	Hsp90 protein binding	2/649	42/18639	0.0476190476190476	1.36759850319172	0.432455509532405	0.628830443214314
GO:0000062	fatty-acyl-CoA binding	1/649	16/18639	0.0625	1.79497303543914	0.432930937068835	0.628830443214314
GO:0005159	insulin-like growth factor receptor binding	1/649	16/18639	0.0625	1.79497303543914	0.432930937068835	0.628830443214314
GO:0005521	lamin binding	1/649	16/18639	0.0625	1.79497303543914	0.432930937068835	0.628830443214314
GO:0008142	oxysterol binding	1/649	16/18639	0.0625	1.79497303543914	0.432930937068835	0.628830443214314
GO:0015385	sodium:proton antiporter activity	1/649	16/18639	0.0625	1.79497303543914	0.432930937068835	0.628830443214314
GO:0015923	mannosidase activity	1/649	16/18639	0.0625	1.79497303543914	0.432930937068835	0.628830443214314
GO:0017070	U6 snRNA binding	1/649	16/18639	0.0625	1.79497303543914	0.432930937068835	0.628830443214314
GO:0097027	ubiquitin-protein transferase activator activity	1/649	16/18639	0.0625	1.79497303543914	0.432930937068835	0.628830443214314
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	1/649	16/18639	0.0625	1.79497303543914	0.432930937068835	0.628830443214314
GO:0008028	monocarboxylic acid transmembrane transporter activity	3/649	70/18639	0.0428571428571429	1.23083865287255	0.442227147767582	0.641300461875175
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	1/649	17/18639	0.0588235294117647	1.68938638629566	0.452692942215284	0.644052103908811
GO:0004659	prenyltransferase activity	1/649	17/18639	0.0588235294117647	1.68938638629566	0.452692942215284	0.644052103908811
GO:0008429	phosphatidylethanolamine binding	1/649	17/18639	0.0588235294117647	1.68938638629566	0.452692942215284	0.644052103908811
GO:0008484	sulfuric ester hydrolase activity	1/649	17/18639	0.0588235294117647	1.68938638629566	0.452692942215284	0.644052103908811
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	1/649	17/18639	0.0588235294117647	1.68938638629566	0.452692942215284	0.644052103908811
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/649	17/18639	0.0588235294117647	1.68938638629566	0.452692942215284	0.644052103908811
GO:0031489	myosin V binding	1/649	17/18639	0.0588235294117647	1.68938638629566	0.452692942215284	0.644052103908811
GO:0032183	SUMO binding	1/649	17/18639	0.0588235294117647	1.68938638629566	0.452692942215284	0.644052103908811
GO:0045236	CXCR chemokine receptor binding	1/649	17/18639	0.0588235294117647	1.68938638629566	0.452692942215284	0.644052103908811
GO:0051787	misfolded protein binding	1/649	17/18639	0.0588235294117647	1.68938638629566	0.452692942215284	0.644052103908811
GO:0070403	NAD+ binding	1/649	17/18639	0.0588235294117647	1.68938638629566	0.452692942215284	0.644052103908811
GO:1901567	fatty acid derivative binding	1/649	17/18639	0.0588235294117647	1.68938638629566	0.452692942215284	0.644052103908811
GO:0016248	channel inhibitor activity	2/649	44/18639	0.0454545454545455	1.30543493486483	0.456162582067212	0.647966376416733
GO:0004715	non-membrane spanning protein tyrosine kinase activity	2/649	45/18639	0.0444444444444444	1.27642526964561	0.467800205780103	0.657703376712081
GO:0141110	transporter inhibitor activity	2/649	45/18639	0.0444444444444444	1.27642526964561	0.467800205780103	0.657703376712081
GO:0000400	four-way junction DNA binding	1/649	18/18639	0.0555555555555556	1.59553158705701	0.471767277974186	0.657703376712081
GO:0003746	translation elongation factor activity	1/649	18/18639	0.0555555555555556	1.59553158705701	0.471767277974186	0.657703376712081
GO:0015172	acidic amino acid transmembrane transporter activity	1/649	18/18639	0.0555555555555556	1.59553158705701	0.471767277974186	0.657703376712081
GO:0016854	racemase and epimerase activity	1/649	18/18639	0.0555555555555556	1.59553158705701	0.471767277974186	0.657703376712081
GO:0034185	apolipoprotein binding	1/649	18/18639	0.0555555555555556	1.59553158705701	0.471767277974186	0.657703376712081
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	1/649	18/18639	0.0555555555555556	1.59553158705701	0.471767277974186	0.657703376712081
GO:0070064	proline-rich region binding	1/649	18/18639	0.0555555555555556	1.59553158705701	0.471767277974186	0.657703376712081
GO:0070628	proteasome binding	1/649	18/18639	0.0555555555555556	1.59553158705701	0.471767277974186	0.657703376712081
GO:1901611	phosphatidylglycerol binding	1/649	18/18639	0.0555555555555556	1.59553158705701	0.471767277974186	0.657703376712081
GO:1990381	ubiquitin-specific protease binding	1/649	18/18639	0.0555555555555556	1.59553158705701	0.471767277974186	0.657703376712081
GO:0016741	transferase activity, transferring one-carbon groups	8/649	215/18639	0.0372093023255814	1.06863510947074	0.474986925017643	0.661170071552336
GO:0003684	damaged DNA binding	3/649	74/18639	0.0405405405405405	1.16430683379836	0.478544426511507	0.665095643626162
GO:0030291	protein serine/threonine kinase inhibitor activity	2/649	46/18639	0.0434782608695652	1.24867689421853	0.479288172908901	0.665104510713582
GO:0005262	calcium channel activity	5/649	131/18639	0.0381679389312977	1.09616673919947	0.481728611536811	0.667464220593246
GO:0005126	cytokine receptor binding	10/649	275/18639	0.0363636363636364	1.04434794789186	0.48979720957003	0.674606330615522
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/649	19/18639	0.0526315789473684	1.5115562403698	0.490177837911609	0.674606330615522
GO:0042577	lipid phosphatase activity	1/649	19/18639	0.0526315789473684	1.5115562403698	0.490177837911609	0.674606330615522
GO:0120227	acyl-CoA binding	1/649	19/18639	0.0526315789473684	1.5115562403698	0.490177837911609	0.674606330615522
GO:0043495	protein-membrane adaptor activity	2/649	47/18639	0.0425531914893617	1.22210930072452	0.490622785902198	0.674606330615522
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	2/649	48/18639	0.0416666666666667	1.19664869029276	0.501800785109129	0.687331670758871
GO:0032266	phosphatidylinositol-3-phosphate binding	2/649	48/18639	0.0416666666666667	1.19664869029276	0.501800785109129	0.687331670758871
GO:0000339	RNA cap binding	1/649	20/18639	0.05	1.43597842835131	0.507947686633166	0.687331670758871
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	1/649	20/18639	0.05	1.43597842835131	0.507947686633166	0.687331670758871
GO:0010851	cyclase regulator activity	1/649	20/18639	0.05	1.43597842835131	0.507947686633166	0.687331670758871
GO:0016004	phospholipase activator activity	1/649	20/18639	0.05	1.43597842835131	0.507947686633166	0.687331670758871
GO:0016408	C-acyltransferase activity	1/649	20/18639	0.05	1.43597842835131	0.507947686633166	0.687331670758871
GO:0016505	peptidase activator activity involved in apoptotic process	1/649	20/18639	0.05	1.43597842835131	0.507947686633166	0.687331670758871
GO:0043024	ribosomal small subunit binding	1/649	20/18639	0.05	1.43597842835131	0.507947686633166	0.687331670758871
GO:0140939	histone H4 methyltransferase activity	1/649	20/18639	0.05	1.43597842835131	0.507947686633166	0.687331670758871
GO:0015297	antiporter activity	5/649	135/18639	0.037037037037037	1.06368772470467	0.508259672279564	0.687331670758871
GO:0015103	inorganic anion transmembrane transporter activity	6/649	165/18639	0.0363636363636364	1.04434794789186	0.515320108566724	0.695836434022733
GO:0033293	monocarboxylic acid binding	3/649	79/18639	0.0379746835443038	1.09061652786175	0.522312968077588	0.702729047222253
GO:0015174	basic amino acid transmembrane transporter activity	1/649	21/18639	0.0476190476190476	1.36759850319172	0.525099088500885	0.702729047222253
GO:0019200	carbohydrate kinase activity	1/649	21/18639	0.0476190476190476	1.36759850319172	0.525099088500885	0.702729047222253
GO:0051010	microtubule plus-end binding	1/649	21/18639	0.0476190476190476	1.36759850319172	0.525099088500885	0.702729047222253
GO:0051428	peptide hormone receptor binding	1/649	21/18639	0.0476190476190476	1.36759850319172	0.525099088500885	0.702729047222253
GO:0070182	DNA polymerase binding	1/649	21/18639	0.0476190476190476	1.36759850319172	0.525099088500885	0.702729047222253
GO:0004620	phospholipase activity	4/649	109/18639	0.036697247706422	1.05392912172573	0.528911692584544	0.706782735868532
GO:0035091	phosphatidylinositol binding	10/649	284/18639	0.0352112676056338	1.01125241433191	0.530913448562967	0.708408181366562
GO:0016247	channel regulator activity	6/649	168/18639	0.0357142857142857	1.02569887739379	0.532979137544222	0.710114006004266
GO:0001618	virus receptor activity	3/649	81/18639	0.037037037037037	1.06368772470467	0.539250262327669	0.714285802473406
GO:0030971	receptor tyrosine kinase binding	3/649	81/18639	0.037037037037037	1.06368772470467	0.539250262327669	0.714285802473406
GO:0004407	histone deacetylase activity	1/649	22/18639	0.0454545454545455	1.30543493486483	0.541653535356774	0.714285802473406
GO:0008649	rRNA methyltransferase activity	1/649	22/18639	0.0454545454545455	1.30543493486483	0.541653535356774	0.714285802473406
GO:0033558	protein lysine deacetylase activity	1/649	22/18639	0.0454545454545455	1.30543493486483	0.541653535356774	0.714285802473406
GO:0034062	5'-3' RNA polymerase activity	1/649	22/18639	0.0454545454545455	1.30543493486483	0.541653535356774	0.714285802473406
GO:0097747	RNA polymerase activity	1/649	22/18639	0.0454545454545455	1.30543493486483	0.541653535356774	0.714285802473406
GO:0141108	transporter regulator activity	6/649	170/18639	0.0352941176470588	1.0136318317774	0.544601016377447	0.717124258061981
GO:0005246	calcium channel regulator activity	2/649	53/18639	0.0377358490566038	1.08375730441608	0.555254977359704	0.724760604474331
GO:0005544	calcium-dependent phospholipid binding	2/649	53/18639	0.0377358490566038	1.08375730441608	0.555254977359704	0.724760604474331
GO:0008146	sulfotransferase activity	2/649	53/18639	0.0377358490566038	1.08375730441608	0.555254977359704	0.724760604474331
GO:0016251	RNA polymerase II general transcription initiation factor activity	2/649	53/18639	0.0377358490566038	1.08375730441608	0.555254977359704	0.724760604474331
GO:0003887	DNA-directed DNA polymerase activity	1/649	23/18639	0.0434782608695652	1.24867689421853	0.557631773287345	0.724760604474331
GO:0008171	O-methyltransferase activity	1/649	23/18639	0.0434782608695652	1.24867689421853	0.557631773287345	0.724760604474331
GO:0016493	C-C chemokine receptor activity	1/649	23/18639	0.0434782608695652	1.24867689421853	0.557631773287345	0.724760604474331
GO:0099186	structural constituent of postsynapse	1/649	23/18639	0.0434782608695652	1.24867689421853	0.557631773287345	0.724760604474331
GO:0140102	catalytic activity, acting on a rRNA	1/649	23/18639	0.0434782608695652	1.24867689421853	0.557631773287345	0.724760604474331
GO:0004527	exonuclease activity	3/649	84/18639	0.0357142857142857	1.02569887739379	0.5639967959396	0.730077052645442
GO:0015485	cholesterol binding	2/649	54/18639	0.037037037037037	1.06368772470467	0.565446252046256	0.730077052645442
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	2/649	54/18639	0.037037037037037	1.06368772470467	0.565446252046256	0.730077052645442
GO:0019955	cytokine binding	5/649	144/18639	0.0347222222222222	0.997207241910632	0.5657865539283	0.730077052645442
GO:0004622	lysophospholipase activity	1/649	24/18639	0.0416666666666667	1.19664869029276	0.573053828462276	0.730077052645442
GO:0005315	phosphate transmembrane transporter activity	1/649	24/18639	0.0416666666666667	1.19664869029276	0.573053828462276	0.730077052645442
GO:0005540	hyaluronic acid binding	1/649	24/18639	0.0416666666666667	1.19664869029276	0.573053828462276	0.730077052645442
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/649	24/18639	0.0416666666666667	1.19664869029276	0.573053828462276	0.730077052645442
GO:0019957	C-C chemokine binding	1/649	24/18639	0.0416666666666667	1.19664869029276	0.573053828462276	0.730077052645442
GO:0030215	semaphorin receptor binding	1/649	24/18639	0.0416666666666667	1.19664869029276	0.573053828462276	0.730077052645442
GO:0030552	cAMP binding	1/649	24/18639	0.0416666666666667	1.19664869029276	0.573053828462276	0.730077052645442
GO:0048027	mRNA 5'-UTR binding	1/649	24/18639	0.0416666666666667	1.19664869029276	0.573053828462276	0.730077052645442
GO:0060229	lipase activator activity	1/649	24/18639	0.0416666666666667	1.19664869029276	0.573053828462276	0.730077052645442
GO:0070840	dynein complex binding	1/649	24/18639	0.0416666666666667	1.19664869029276	0.573053828462276	0.730077052645442
GO:1990782	protein tyrosine kinase binding	4/649	117/18639	0.0341880341880342	0.981865592035084	0.585119889681924	0.741707702007534
GO:0030170	pyridoxal phosphate binding	2/649	56/18639	0.0357142857142857	1.02569887739379	0.585320626414561	0.741707702007534
GO:0003707	nuclear steroid receptor activity	1/649	25/18639	0.04	1.14878274268105	0.587939032079143	0.741707702007534
GO:0004709	MAP kinase kinase kinase activity	1/649	25/18639	0.04	1.14878274268105	0.587939032079143	0.741707702007534
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/649	25/18639	0.04	1.14878274268105	0.587939032079143	0.741707702007534
GO:0047617	fatty acyl-CoA hydrolase activity	1/649	25/18639	0.04	1.14878274268105	0.587939032079143	0.741707702007534
GO:0120020	cholesterol transfer activity	1/649	25/18639	0.04	1.14878274268105	0.587939032079143	0.741707702007534
GO:0070279	vitamin B6 binding	2/649	57/18639	0.0350877192982456	1.00770416024653	0.595002791843299	0.748319630977293
GO:0004197	cysteine-type endopeptidase activity	3/649	88/18639	0.0340909090909091	0.97907620114862	0.595699926854137	0.748319630977293
GO:0001637	G protein-coupled chemoattractant receptor activity	1/649	26/18639	0.0384615384615385	1.10459879103947	0.602306044445138	0.748319630977293
GO:0004435	phosphatidylinositol phospholipase C activity	1/649	26/18639	0.0384615384615385	1.10459879103947	0.602306044445138	0.748319630977293
GO:0004950	chemokine receptor activity	1/649	26/18639	0.0384615384615385	1.10459879103947	0.602306044445138	0.748319630977293
GO:0016289	acyl-CoA hydrolase activity	1/649	26/18639	0.0384615384615385	1.10459879103947	0.602306044445138	0.748319630977293
GO:0019865	immunoglobulin binding	1/649	26/18639	0.0384615384615385	1.10459879103947	0.602306044445138	0.748319630977293
GO:0050750	low-density lipoprotein particle receptor binding	1/649	26/18639	0.0384615384615385	1.10459879103947	0.602306044445138	0.748319630977293
GO:0051139	metal cation:proton antiporter activity	1/649	26/18639	0.0384615384615385	1.10459879103947	0.602306044445138	0.748319630977293
GO:0052742	phosphatidylinositol kinase activity	1/649	26/18639	0.0384615384615385	1.10459879103947	0.602306044445138	0.748319630977293
GO:0120014	phospholipid transfer activity	1/649	26/18639	0.0384615384615385	1.10459879103947	0.602306044445138	0.748319630977293
GO:0046873	metal ion transmembrane transporter activity	15/649	450/18639	0.0333333333333333	0.957318952234206	0.605883333769428	0.751728702971147
GO:0004540	RNA nuclease activity	4/649	121/18639	0.0330578512396694	0.949407225356238	0.611719150058156	0.756887069070585
GO:0015108	chloride transmembrane transporter activity	4/649	121/18639	0.0330578512396694	0.949407225356238	0.611719150058156	0.756887069070585
GO:0015459	potassium channel regulator activity	2/649	59/18639	0.0338983050847458	0.973544697187329	0.613856489735767	0.757204272696813
GO:0036002	pre-mRNA binding	2/649	59/18639	0.0338983050847458	0.973544697187329	0.613856489735767	0.757204272696813
GO:0005385	zinc ion transmembrane transporter activity	1/649	27/18639	0.037037037037037	1.06368772470467	0.616172878225566	0.757204272696813
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	1/649	27/18639	0.037037037037037	1.06368772470467	0.616172878225566	0.757204272696813
GO:0035255	ionotropic glutamate receptor binding	1/649	27/18639	0.037037037037037	1.06368772470467	0.616172878225566	0.757204272696813
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	4/649	122/18639	0.0327868852459016	0.941625198918892	0.618202267309023	0.757961741325812
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	3/649	91/18639	0.032967032967033	0.946798963748116	0.618469890926605	0.757961741325812
GO:0052689	carboxylic ester hydrolase activity	3/649	92/18639	0.0326086956521739	0.936507670663898	0.625863822970777	0.765982589307518
GO:0016866	intramolecular transferase activity	1/649	28/18639	0.0357142857142857	1.02569887739379	0.629556920887914	0.767378841406619
GO:0045499	chemorepellent activity	1/649	28/18639	0.0357142857142857	1.02569887739379	0.629556920887914	0.767378841406619
GO:0050698	proteoglycan sulfotransferase activity	1/649	28/18639	0.0357142857142857	1.02569887739379	0.629556920887914	0.767378841406619
GO:0019905	syntaxin binding	2/649	61/18639	0.0327868852459016	0.941625198918892	0.632030986724326	0.769354858333795
GO:0004181	metallocarboxypeptidase activity	1/649	29/18639	0.0344827586206897	0.99032995058711	0.642474956369282	0.777869007577305
GO:0004629	phospholipase C activity	1/649	29/18639	0.0344827586206897	0.99032995058711	0.642474956369282	0.777869007577305
GO:0035250	UDP-galactosyltransferase activity	1/649	29/18639	0.0344827586206897	0.99032995058711	0.642474956369282	0.777869007577305
GO:0043236	laminin binding	1/649	29/18639	0.0344827586206897	0.99032995058711	0.642474956369282	0.777869007577305
GO:1901682	sulfur compound transmembrane transporter activity	2/649	63/18639	0.0317460317460317	0.911732335461149	0.64953081412959	0.785357633170094
GO:0098918	structural constituent of synapse	1/649	30/18639	0.0333333333333333	0.957318952234206	0.654943185994018	0.790841705176177
GO:0099106	ion channel regulator activity	5/649	160/18639	0.03125	0.897486517719569	0.658741399884485	0.794364629272467
GO:0160215	deacylase activity	2/649	65/18639	0.0307692307692308	0.883679032831575	0.666363060686528	0.797550732795188
GO:0005310	dicarboxylic acid transmembrane transporter activity	1/649	31/18639	0.032258064516129	0.926437695710522	0.666977248667449	0.797550732795188
GO:0070273	phosphatidylinositol-4-phosphate binding	1/649	31/18639	0.032258064516129	0.926437695710522	0.666977248667449	0.797550732795188
GO:0070325	lipoprotein particle receptor binding	1/649	31/18639	0.032258064516129	0.926437695710522	0.666977248667449	0.797550732795188
GO:0072349	modified amino acid transmembrane transporter activity	1/649	31/18639	0.032258064516129	0.926437695710522	0.666977248667449	0.797550732795188
GO:0016298	lipase activity	4/649	130/18639	0.0307692307692308	0.883679032831575	0.667572952616815	0.797550732795188
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	4/649	130/18639	0.0307692307692308	0.883679032831575	0.667572952616815	0.797550732795188
GO:0008378	galactosyltransferase activity	1/649	32/18639	0.03125	0.897486517719569	0.678592240370739	0.804323522752177
GO:0015106	bicarbonate transmembrane transporter activity	1/649	32/18639	0.03125	0.897486517719569	0.678592240370739	0.804323522752177
GO:0031369	translation initiation factor binding	1/649	32/18639	0.03125	0.897486517719569	0.678592240370739	0.804323522752177
GO:0071813	lipoprotein particle binding	1/649	32/18639	0.03125	0.897486517719569	0.678592240370739	0.804323522752177
GO:0071814	protein-lipid complex binding	1/649	32/18639	0.03125	0.897486517719569	0.678592240370739	0.804323522752177
GO:0120015	sterol transfer activity	1/649	32/18639	0.03125	0.897486517719569	0.678592240370739	0.804323522752177
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	2/649	67/18639	0.0298507462686567	0.857300554239588	0.682537002363765	0.807937501485716
GO:0019239	deaminase activity	1/649	33/18639	0.0303030303030303	0.870289956576551	0.689802732981014	0.811894696289213
GO:0019956	chemokine binding	1/649	33/18639	0.0303030303030303	0.870289956576551	0.689802732981014	0.811894696289213
GO:0015399	primary active transmembrane transporter activity	5/649	166/18639	0.0301204819277108	0.865047245994765	0.690093030774743	0.811894696289213
GO:0003777	microtubule motor activity	2/649	68/18639	0.0294117647058824	0.844693193147829	0.690380523341271	0.811894696289213
GO:0140223	general transcription initiation factor activity	2/649	68/18639	0.0294117647058824	0.844693193147829	0.690380523341271	0.811894696289213
GO:0008376	acetylgalactosaminyltransferase activity	1/649	34/18639	0.0294117647058824	0.844693193147829	0.700622792440077	0.816488060440503
GO:0016831	carboxy-lyase activity	1/649	34/18639	0.0294117647058824	0.844693193147829	0.700622792440077	0.816488060440503
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	1/649	34/18639	0.0294117647058824	0.844693193147829	0.700622792440077	0.816488060440503
GO:0019825	oxygen binding	1/649	34/18639	0.0294117647058824	0.844693193147829	0.700622792440077	0.816488060440503
GO:0051427	hormone receptor binding	1/649	34/18639	0.0294117647058824	0.844693193147829	0.700622792440077	0.816488060440503
GO:0052866	phosphatidylinositol phosphate phosphatase activity	1/649	34/18639	0.0294117647058824	0.844693193147829	0.700622792440077	0.816488060440503
GO:0090482	vitamin transmembrane transporter activity	1/649	34/18639	0.0294117647058824	0.844693193147829	0.700622792440077	0.816488060440503
GO:0019838	growth factor binding	4/649	136/18639	0.0294117647058824	0.844693193147829	0.701617062564974	0.81659172959175
GO:0005154	epidermal growth factor receptor binding	1/649	35/18639	0.0285714285714286	0.820559101915034	0.711065996294224	0.825458852840913
GO:0043015	gamma-tubulin binding	1/649	35/18639	0.0285714285714286	0.820559101915034	0.711065996294224	0.825458852840913
GO:0042379	chemokine receptor binding	2/649	72/18639	0.0277777777777778	0.797765793528505	0.720168594573843	0.834951249750137
GO:0055106	ubiquitin-protein transferase regulator activity	1/649	36/18639	0.0277777777777778	0.797765793528505	0.721145450626897	0.835010521778512
GO:0005496	steroid binding	3/649	108/18639	0.0277777777777778	0.797765793528505	0.730623004963581	0.841951690137241
GO:0019213	deacetylase activity	1/649	37/18639	0.027027027027027	0.776204555865573	0.730873806405166	0.841951690137241
GO:0030551	cyclic nucleotide binding	1/649	37/18639	0.027027027027027	0.776204555865573	0.730873806405166	0.841951690137241
GO:0042805	actinin binding	1/649	37/18639	0.027027027027027	0.776204555865573	0.730873806405166	0.841951690137241
GO:0035064	methylated histone binding	2/649	74/18639	0.027027027027027	0.776204555865573	0.734135716913471	0.844630633489733
GO:0005109	frizzled binding	1/649	38/18639	0.0263157894736842	0.7557781201849	0.740263275260291	0.849513326062065
GO:0042887	amide transmembrane transporter activity	1/649	38/18639	0.0263157894736842	0.7557781201849	0.740263275260291	0.849513326062065
GO:0004222	metalloendopeptidase activity	3/649	110/18639	0.0272727272727273	0.783260960918896	0.741944590350682	0.850360890084263
GO:0017022	myosin binding	2/649	76/18639	0.0263157894736842	0.7557781201849	0.747505236322743	0.854562386772007
GO:0140034	methylation-dependent protein binding	2/649	76/18639	0.0263157894736842	0.7557781201849	0.747505236322743	0.854562386772007
GO:0071949	FAD binding	1/649	40/18639	0.025	0.717989214175655	0.758072292924919	0.865545833187693
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	1/649	41/18639	0.024390243902439	0.70047728212259	0.766514202806726	0.871915647668484
GO:0017080	sodium channel regulator activity	1/649	41/18639	0.024390243902439	0.70047728212259	0.766514202806726	0.871915647668484
GO:0008509	monoatomic anion transmembrane transporter activity	4/649	149/18639	0.0268456375838926	0.770995129316139	0.766551118183046	0.871915647668484
GO:0061135	endopeptidase regulator activity	5/649	184/18639	0.0271739130434783	0.780423058886581	0.772022261600032	0.876491011316288
GO:0048306	calcium-dependent protein binding	2/649	80/18639	0.025	0.717989214175655	0.772517022169012	0.876491011316288
GO:0042056	chemoattractant activity	1/649	42/18639	0.0238095238095238	0.683799251595862	0.774661975813417	0.877820480130279
GO:0008200	ion channel inhibitor activity	1/649	43/18639	0.0232558139534884	0.667896943419214	0.782525845130892	0.884509163293314
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/649	43/18639	0.0232558139534884	0.667896943419214	0.782525845130892	0.884509163293314
GO:0030165	PDZ domain binding	2/649	83/18639	0.0240963855421687	0.692037796795812	0.789831758316588	0.889743259661767
GO:0016790	thiolester hydrolase activity	1/649	44/18639	0.0227272727272727	0.652717467432414	0.790115688457955	0.889743259661767
GO:0019205	nucleobase-containing compound kinase activity	1/649	44/18639	0.0227272727272727	0.652717467432414	0.790115688457955	0.889743259661767
GO:0008009	chemokine activity	1/649	45/18639	0.0222222222222222	0.638212634822804	0.797441040336997	0.894641565154193
GO:0046915	transition metal ion transmembrane transporter activity	1/649	45/18639	0.0222222222222222	0.638212634822804	0.797441040336997	0.894641565154193
GO:0051539	4 iron, 4 sulfur cluster binding	1/649	45/18639	0.0222222222222222	0.638212634822804	0.797441040336997	0.894641565154193
GO:0004180	carboxypeptidase activity	1/649	46/18639	0.0217391304347826	0.624338447109265	0.804511104057621	0.90033376657565
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/649	46/18639	0.0217391304347826	0.624338447109265	0.804511104057621	0.90033376657565
GO:0016209	antioxidant activity	2/649	86/18639	0.0232558139534884	0.667896943419214	0.80597443814638	0.900853709055805
GO:0015079	potassium ion transmembrane transporter activity	4/649	160/18639	0.025	0.717989214175655	0.812409736769714	0.906922750700844
GO:0005004	GPI-linked ephrin receptor activity	1/649	49/18639	0.0204081632653061	0.586113644225024	0.824276868918274	0.908921437364649
GO:0005008	hepatocyte growth factor receptor activity	1/649	49/18639	0.0204081632653061	0.586113644225024	0.824276868918274	0.908921437364649
GO:0005009	insulin receptor activity	1/649	49/18639	0.0204081632653061	0.586113644225024	0.824276868918274	0.908921437364649
GO:0005011	macrophage colony-stimulating factor receptor activity	1/649	49/18639	0.0204081632653061	0.586113644225024	0.824276868918274	0.908921437364649
GO:0005018	platelet-derived growth factor alpha-receptor activity	1/649	49/18639	0.0204081632653061	0.586113644225024	0.824276868918274	0.908921437364649
GO:0005020	stem cell factor receptor activity	1/649	49/18639	0.0204081632653061	0.586113644225024	0.824276868918274	0.908921437364649
GO:0008288	boss receptor activity	1/649	49/18639	0.0204081632653061	0.586113644225024	0.824276868918274	0.908921437364649
GO:0036332	placental growth factor receptor activity	1/649	49/18639	0.0204081632653061	0.586113644225024	0.824276868918274	0.908921437364649
GO:0038062	protein tyrosine kinase collagen receptor activity	1/649	49/18639	0.0204081632653061	0.586113644225024	0.824276868918274	0.908921437364649
GO:0060175	brain-derived neurotrophic factor receptor activity	1/649	49/18639	0.0204081632653061	0.586113644225024	0.824276868918274	0.908921437364649
GO:0005006	epidermal growth factor receptor activity	1/649	50/18639	0.02	0.574391371340524	0.830411581778523	0.910123021584724
GO:0005007	fibroblast growth factor receptor activity	1/649	50/18639	0.02	0.574391371340524	0.830411581778523	0.910123021584724
GO:0005017	platelet-derived growth factor receptor activity	1/649	50/18639	0.02	0.574391371340524	0.830411581778523	0.910123021584724
GO:0005019	platelet-derived growth factor beta-receptor activity	1/649	50/18639	0.02	0.574391371340524	0.830411581778523	0.910123021584724
GO:0048020	CCR chemokine receptor binding	1/649	50/18639	0.02	0.574391371340524	0.830411581778523	0.910123021584724
GO:0005010	insulin-like growth factor receptor activity	1/649	51/18639	0.0196078431372549	0.563128795431886	0.836332442686896	0.912178794804813
GO:0005021	vascular endothelial growth factor receptor activity	1/649	51/18639	0.0196078431372549	0.563128795431886	0.836332442686896	0.912178794804813
GO:0005030	neurotrophin receptor activity	1/649	51/18639	0.0196078431372549	0.563128795431886	0.836332442686896	0.912178794804813
GO:0016830	carbon-carbon lyase activity	1/649	51/18639	0.0196078431372549	0.563128795431886	0.836332442686896	0.912178794804813
GO:0005003	ephrin receptor activity	1/649	53/18639	0.0188679245283019	0.541878652208041	0.84756212446505	0.918871437821484
GO:0005005	transmembrane-ephrin receptor activity	1/649	53/18639	0.0188679245283019	0.541878652208041	0.84756212446505	0.918871437821484
GO:0016860	intramolecular oxidoreductase activity	1/649	53/18639	0.0188679245283019	0.541878652208041	0.84756212446505	0.918871437821484
GO:0017046	peptide hormone binding	1/649	53/18639	0.0188679245283019	0.541878652208041	0.84756212446505	0.918871437821484
GO:0038064	collagen receptor activity	1/649	53/18639	0.0188679245283019	0.541878652208041	0.84756212446505	0.918871437821484
GO:0005539	glycosaminoglycan binding	6/649	242/18639	0.0247933884297521	0.712055419017178	0.851169042357825	0.921674041064536
GO:0051287	NAD binding	1/649	54/18639	0.0185185185185185	0.531843862352337	0.852885065454083	0.922257935517264
GO:0008201	heparin binding	4/649	172/18639	0.0232558139534884	0.667896943419214	0.85375318864403	0.922257935517264
GO:0003735	structural constituent of ribosome	4/649	175/18639	0.0228571428571429	0.656447281532027	0.86279388206783	0.930909188546869
GO:0070851	growth factor receptor binding	3/649	139/18639	0.0215827338129496	0.619846803604882	0.866790319068707	0.934039239283743
GO:0004601	peroxidase activity	1/649	57/18639	0.0175438596491228	0.503852080123267	0.867765945143877	0.934039239283743
GO:0020037	heme binding	3/649	142/18639	0.0211267605633803	0.606751448599145	0.876047686382012	0.939324551492195
GO:0016853	isomerase activity	4/649	180/18639	0.0222222222222222	0.638212634822804	0.876799610168643	0.939324551492195
GO:0001786	phosphatidylserine binding	1/649	59/18639	0.0169491525423729	0.486772348593664	0.876841765361894	0.939324551492195
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	1/649	59/18639	0.0169491525423729	0.486772348593664	0.876841765361894	0.939324551492195
GO:0004714	transmembrane receptor protein tyrosine kinase activity	1/649	60/18639	0.0166666666666667	0.478659476117103	0.881143686474926	0.942813292052649
GO:0015026	coreceptor activity	1/649	61/18639	0.0163934426229508	0.470812599459446	0.885295564804102	0.945013727163669
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	1/649	61/18639	0.0163934426229508	0.470812599459446	0.885295564804102	0.945013727163669
GO:0008237	metallopeptidase activity	4/649	184/18639	0.0217391304347826	0.624338447109265	0.887097462811675	0.945083174962471
GO:0004497	monooxygenase activity	2/649	106/18639	0.0188679245283019	0.541878652208041	0.887995377985175	0.945083174962471
GO:0015078	proton transmembrane transporter activity	4/649	185/18639	0.0216216216216216	0.620963644692458	0.889551680203035	0.945083174962471
GO:1901981	phosphatidylinositol phosphate binding	4/649	185/18639	0.0216216216216216	0.620963644692458	0.889551680203035	0.945083174962471
GO:0005507	copper ion binding	1/649	63/18639	0.0158730158730159	0.455866167730574	0.893169913044551	0.947810895960218
GO:0001664	G protein-coupled receptor binding	7/649	297/18639	0.0235690235690236	0.676892188448429	0.896008562297494	0.949705902693701
GO:1902936	phosphatidylinositol bisphosphate binding	2/649	111/18639	0.018018018018018	0.517469703910382	0.902751900474723	0.954780494456716
GO:0046906	tetrapyrrole binding	3/649	152/18639	0.0197368421052632	0.566833590138675	0.90291326138756	0.954780494456716
GO:0008235	metalloexopeptidase activity	1/649	66/18639	0.0151515151515152	0.435144978288276	0.90398097521296	0.954790210353735
GO:0016757	glycosyltransferase activity	6/649	267/18639	0.0224719101123595	0.645383563303959	0.906786874397128	0.954979277251297
GO:0008173	RNA methyltransferase activity	1/649	67/18639	0.0149253731343284	0.428650277119794	0.907336186922796	0.954979277251297
GO:0016500	protein-hormone receptor activity	1/649	67/18639	0.0149253731343284	0.428650277119794	0.907336186922796	0.954979277251297
GO:0005125	cytokine activity	5/649	234/18639	0.0213675213675214	0.613665995021927	0.913737993917282	0.960596352579707
GO:1901681	sulfur compound binding	6/649	275/18639	0.0218181818181818	0.626608768735117	0.920314537245729	0.965331214089751
GO:0022853	active monoatomic ion transmembrane transporter activity	2/649	118/18639	0.0169491525423729	0.486772348593664	0.920382310551204	0.965331214089751
GO:0004866	endopeptidase inhibitor activity	3/649	161/18639	0.0186335403726708	0.53514724037937	0.922474111478646	0.966401450120486
GO:0008083	growth factor activity	3/649	162/18639	0.0185185185185185	0.531843862352337	0.924409396478863	0.966955419426092
GO:0004521	RNA endonuclease activity	1/649	73/18639	0.0136986301369863	0.393418747493509	0.925146925681505	0.966955419426092
GO:0051536	iron-sulfur cluster binding	1/649	76/18639	0.0131578947368421	0.37788906009245	0.932725892840791	0.973748559424066
GO:0051540	metal cluster binding	1/649	77/18639	0.012987012987013	0.372981409961379	0.935077931603185	0.974064251472626
GO:0004518	nuclease activity	4/649	209/18639	0.0191387559808612	0.549656814679927	0.935941853421138	0.974064251472626
GO:0030414	peptidase inhibitor activity	3/649	169/18639	0.0177514792899408	0.509814826633601	0.936763400880629	0.974064251472626
GO:0019199	transmembrane receptor protein kinase activity	1/649	78/18639	0.0128205128205128	0.368199597013156	0.937347860618891	0.974064251472626
GO:0000049	tRNA binding	1/649	80/18639	0.0125	0.358994607087827	0.94165273852686	0.977411703281045
GO:0005254	chloride channel activity	1/649	83/18639	0.0120481927710843	0.346018898397906	0.947562621078836	0.982415499095529
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	1/649	86/18639	0.0116279069767442	0.333948471709607	0.952874731277024	0.984551813492528
GO:0050660	flavin adenine dinucleotide binding	1/649	86/18639	0.0116279069767442	0.333948471709607	0.952874731277024	0.984551813492528
GO:0099094	ligand-gated monoatomic cation channel activity	2/649	136/18639	0.0147058823529412	0.422346596573915	0.952897708624143	0.984551813492528
GO:0140101	catalytic activity, acting on a tRNA	2/649	139/18639	0.0143884892086331	0.413231202403255	0.956900079676286	0.987555917469119
GO:0031406	carboxylic acid binding	3/649	187/18639	0.0160427807486631	0.460741741716998	0.96047431848787	0.98907088725726
GO:0072341	modified amino acid binding	1/649	91/18639	0.010989010989011	0.315599654582706	0.960561083411707	0.98907088725726
GO:0043177	organic acid binding	3/649	189/18639	0.0158730158730159	0.455866167730574	0.962519228211332	0.98964158617544
GO:0008194	UDP-glycosyltransferase activity	2/649	145/18639	0.0137931034482759	0.396131980234844	0.963949977616702	0.98964158617544
GO:0042562	hormone binding	1/649	94/18639	0.0106382978723404	0.30552732518113	0.964558061198393	0.98964158617544
GO:0008236	serine-type peptidase activity	3/649	194/18639	0.0154639175257732	0.444117039696281	0.967204796292944	0.98964158617544
GO:0030246	carbohydrate binding	5/649	280/18639	0.0178571428571429	0.512849438696896	0.968730190057014	0.98964158617544
GO:0019842	vitamin binding	2/649	150/18639	0.0133333333333333	0.382927580893683	0.968965999806654	0.98964158617544
GO:0016758	hexosyltransferase activity	3/649	197/18639	0.0152284263959391	0.437353836046084	0.96974499564171	0.98964158617544
GO:0017171	serine hydrolase activity	3/649	198/18639	0.0151515151515152	0.435144978288276	0.970549589801577	0.98964158617544
GO:0005506	iron ion binding	2/649	154/18639	0.012987012987013	0.372981409961379	0.972488150608927	0.98964158617544
GO:0008238	exopeptidase activity	1/649	102/18639	0.00980392156862745	0.281564397715943	0.973348187294825	0.98964158617544
GO:0004175	endopeptidase activity	8/649	405/18639	0.0197530864197531	0.567300119842493	0.973352478406894	0.98964158617544
GO:0005253	monoatomic anion channel activity	1/649	103/18639	0.00970873786407767	0.278830762786662	0.974281295480921	0.98964158617544
GO:0005178	integrin binding	2/649	161/18639	0.0124223602484472	0.35676482691958	0.977744893911433	0.992042625768405
GO:0016874	ligase activity	2/649	167/18639	0.0119760479041916	0.343946928946421	0.981465338560947	0.99469857908087
GO:0004252	serine-type endopeptidase activity	2/649	176/18639	0.0113636363636364	0.326358733716207	0.985939720885141	0.99811181620471
GO:0004519	endonuclease activity	1/649	127/18639	0.0078740157480315	0.226138335173435	0.989072270774731	0.999165801795699
GO:0015276	ligand-gated monoatomic ion channel activity	2/649	186/18639	0.010752688172043	0.308812565236841	0.989681938368916	0.999165801795699
GO:0022834	ligand-gated channel activity	2/649	188/18639	0.0106382978723404	0.30552732518113	0.990304020848509	0.999165801795699
GO:0033218	amide binding	3/649	247/18639	0.0121457489878543	0.348820670854569	0.992469873527668	0.999505348860037
GO:0005261	monoatomic cation channel activity	5/649	341/18639	0.0146627565982405	0.421108043504783	0.992856754521722	0.999505348860037
GO:0005201	extracellular matrix structural constituent	1/649	168/18639	0.00595238095238095	0.170949812898965	0.997474349371836	0.999992231972488
GO:0005216	monoatomic ion channel activity	6/649	448/18639	0.0133928571428571	0.384637079022672	0.998536615016134	0.999992231972488
GO:0045182	translation regulator activity	4/649	356/18639	0.0112359550561798	0.32269178165198	0.998624706638957	0.999992231972488
GO:0016829	lyase activity	1/649	200/18639	0.005	0.143597842835131	0.99919673084053	0.999992231972488
GO:0022836	gated channel activity	2/649	318/18639	0.00628930817610063	0.18062621740268	0.999853546010403	0.999992231972488
GO:0030371	translation repressor activity	1/649	329/18639	0.00303951367781155	0.0872935214803228	0.999992231972488	0.999992231972488