ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003712	transcription coregulator activity	123/2144	495/18639	0.248484848484848	2.16021879240163	3.80758947419365e-17	4.75567925326787e-14
GO:0140297	DNA-binding transcription factor binding	111/2144	488/18639	0.227459016393443	1.97742938738684	8.02363397183922e-13	5.0107594154136e-10
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	83/2144	349/18639	0.237822349570201	2.06752368173459	6.12007362760326e-11	2.54799065362549e-08
GO:0030695	GTPase regulator activity	105/2144	489/18639	0.214723926380368	1.8667160745353	1.26861141939507e-10	3.1623164419827e-08
GO:0060589	nucleoside-triphosphatase regulator activity	105/2144	490/18639	0.214285714285714	1.86290644989339	1.43634285490887e-10	3.1623164419827e-08
GO:0106310	protein serine kinase activity	84/2144	361/18639	0.232686980609418	2.02287902592302	1.51912719390682e-10	3.1623164419827e-08
GO:0019209	kinase activator activity	45/2144	148/18639	0.304054054054054	2.64331320592981	4.5934848875009e-10	8.19608946355518e-08
GO:0003714	transcription corepressor activity	54/2144	204/18639	0.264705882352941	2.30123737928007	2.54224347017916e-09	3.96907761781721e-07
GO:0019207	kinase regulator activity	68/2144	287/18639	0.236933797909408	2.05979900150814	3.84103366027702e-09	5.33050115742888e-07
GO:0004674	protein serine/threonine kinase activity	90/2144	433/18639	0.207852193995381	1.80697623315294	1.41749823835025e-08	1.77045529969946e-06
GO:0051020	GTPase binding	71/2144	315/18639	0.225396825396825	1.95950159914712	1.62324241025544e-08	1.84311797309913e-06
GO:0019903	protein phosphatase binding	41/2144	144/18639	0.284722222222222	2.47525069962687	2.22200492716911e-08	2.27715756514723e-06
GO:0030295	protein kinase activator activity	40/2144	139/18639	0.287769784172662	2.50174487275851	2.37013997973691e-08	2.27715756514723e-06
GO:0019902	phosphatase binding	48/2144	190/18639	0.252631578947368	2.19626865671642	9.26623842664752e-08	8.26680842491625e-06
GO:0140996	histone H3 kinase activity	75/2144	357/18639	0.210084033613445	1.8263788724445	1.43374119629105e-07	1.19382850277835e-05
GO:0031267	small GTPase binding	63/2144	283/18639	0.222614840989399	1.935316241232	1.65493864690269e-07	1.29188648123842e-05
GO:0045296	cadherin binding	71/2144	334/18639	0.212574850299401	1.84803294530342	1.90400407493079e-07	1.39888299387562e-05
GO:0035173	histone kinase activity	75/2144	360/18639	0.208333333333333	1.81115904850746	2.03869204510066e-07	1.40198828218056e-05
GO:0141003	histone H2AX kinase activity	74/2144	354/18639	0.209039548022599	1.81729857070579	2.13272837161174e-07	1.40198828218056e-05
GO:0019887	protein kinase regulator activity	58/2144	255/18639	0.227450980392157	1.97735952589991	2.35666714828124e-07	1.47173863410164e-05
GO:0023026	MHC class II protein complex binding	14/2144	27/18639	0.518518518518518	4.5077736318408	3.17660235311091e-07	1.8893220662074e-05
GO:0140857	histone H3T45 kinase activity	56/2144	246/18639	0.227642276422764	1.97902257007645	3.67083920162202e-07	2.08403552855723e-05
GO:0035403	histone H3T6 kinase activity	56/2144	247/18639	0.226720647773279	1.97101033295063	4.22413654971233e-07	2.11571229675831e-05
GO:0016922	nuclear receptor binding	37/2144	137/18639	0.27007299270073	2.3478966935396	4.57946847040838e-07	2.11571229675831e-05
GO:0004679	AMP-activated protein kinase activity	56/2144	248/18639	0.225806451612903	1.96306271064035	4.8551222565092e-07	2.11571229675831e-05
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	55/2144	243/18639	0.226337448559671	1.96767896627971	5.65389286301224e-07	2.11571229675831e-05
GO:0140375	immune receptor activity	40/2144	156/18639	0.256410256410256	2.22911882893226	7.02148173157211e-07	2.11571229675831e-05
GO:0004676	3-phosphoinositide-dependent protein kinase activity	55/2144	245/18639	0.224489795918367	1.95161628084069	7.45326990050967e-07	2.11571229675831e-05
GO:0004711	ribosomal protein S6 kinase activity	55/2144	245/18639	0.224489795918367	1.95161628084069	7.45326990050967e-07	2.11571229675831e-05
GO:0035175	histone H3S10 kinase activity	55/2144	245/18639	0.224489795918367	1.95161628084069	7.45326990050967e-07	2.11571229675831e-05
GO:0035979	histone H2AXS139 kinase activity	55/2144	245/18639	0.224489795918367	1.95161628084069	7.45326990050967e-07	2.11571229675831e-05
GO:0044022	histone H3S28 kinase activity	55/2144	245/18639	0.224489795918367	1.95161628084069	7.45326990050967e-07	2.11571229675831e-05
GO:0044023	histone H4S1 kinase activity	55/2144	245/18639	0.224489795918367	1.95161628084069	7.45326990050967e-07	2.11571229675831e-05
GO:0044024	histone H2AS1 kinase activity	55/2144	245/18639	0.224489795918367	1.95161628084069	7.45326990050967e-07	2.11571229675831e-05
GO:0044025	histone H2BS14 kinase activity	55/2144	245/18639	0.224489795918367	1.95161628084069	7.45326990050967e-07	2.11571229675831e-05
GO:0072354	histone H3T3 kinase activity	55/2144	245/18639	0.224489795918367	1.95161628084069	7.45326990050967e-07	2.11571229675831e-05
GO:0072371	histone H2AS121 kinase activity	55/2144	245/18639	0.224489795918367	1.95161628084069	7.45326990050967e-07	2.11571229675831e-05
GO:0072518	Rho-dependent protein serine/threonine kinase activity	55/2144	245/18639	0.224489795918367	1.95161628084069	7.45326990050967e-07	2.11571229675831e-05
GO:0140823	histone H2BS36 kinase activity	55/2144	245/18639	0.224489795918367	1.95161628084069	7.45326990050967e-07	2.11571229675831e-05
GO:0140855	histone H3S57 kinase activity	55/2144	245/18639	0.224489795918367	1.95161628084069	7.45326990050967e-07	2.11571229675831e-05
GO:0140995	histone H2A kinase activity	55/2144	245/18639	0.224489795918367	1.95161628084069	7.45326990050967e-07	2.11571229675831e-05
GO:0140997	histone H4 kinase activity	55/2144	245/18639	0.224489795918367	1.95161628084069	7.45326990050967e-07	2.11571229675831e-05
GO:0140998	histone H2B kinase activity	55/2144	245/18639	0.224489795918367	1.95161628084069	7.45326990050967e-07	2.11571229675831e-05
GO:1990244	histone H2AT120 kinase activity	55/2144	245/18639	0.224489795918367	1.95161628084069	7.45326990050967e-07	2.11571229675831e-05
GO:0004677	DNA-dependent protein kinase activity	55/2144	246/18639	0.223577235772358	1.94368288132508	8.54245151537262e-07	2.33212920613021e-05
GO:0019787	ubiquitin-like protein transferase activity	91/2144	479/18639	0.189979123173278	1.65159555822142	8.58910676397036e-07	2.33212920613021e-05
GO:0035402	histone H3T11 kinase activity	55/2144	247/18639	0.222672064777328	1.93581371986223	9.77946882324401e-07	2.59884182132591e-05
GO:0070063	RNA polymerase binding	21/2144	59/18639	0.355932203389831	3.09431918795851	1.15137198521869e-06	2.99596585320447e-05
GO:0005085	guanyl-nucleotide exchange factor activity	52/2144	230/18639	0.226086956521739	1.96550129785853	1.17918867218295e-06	3.00572786031939e-05
GO:0004842	ubiquitin-protein transferase activity	85/2144	449/18639	0.189309576837416	1.64577481467939	2.26848299792453e-06	5.66667052881548e-05
GO:0043024	ribosomal small subunit binding	11/2144	20/18639	0.55	4.7814598880597	2.83263126625363e-06	6.93716951284467e-05
GO:0003713	transcription coactivator activity	55/2144	256/18639	0.21484375	1.86775776877332	3.14074912299933e-06	7.54383779735802e-05
GO:1990226	histone methyltransferase binding	10/2144	17/18639	0.588235294117647	5.1138608428446	3.59339794637997e-06	8.46821516043128e-05
GO:0016755	aminoacyltransferase activity	91/2144	496/18639	0.183467741935484	1.59498845239528	3.92252609871704e-06	9.07265758758812e-05
GO:0005096	GTPase activator activity	57/2144	271/18639	0.210332103321033	1.82853548218318	4.19215039239483e-06	9.51999243654754e-05
GO:0140030	modification-dependent protein binding	41/2144	173/18639	0.236994219653179	2.06032428177034	4.5015368655058e-06	0.000100400349018156
GO:0042605	peptide antigen binding	17/2144	45/18639	0.377777777777778	3.28423507462687	4.68779405035969e-06	0.000102720259103496
GO:0042393	histone binding	53/2144	247/18639	0.214574898785425	1.86542049368542	4.89274197757958e-06	0.000105362667758567
GO:0003924	GTPase activity	66/2144	331/18639	0.199395770392749	1.73345977814853	5.19001232785937e-06	0.000109869921991464
GO:0023023	MHC protein complex binding	15/2144	37/18639	0.405405405405405	3.52441760790641	6.1252392010794e-06	0.00012750706270247
GO:0042277	peptide binding	53/2144	249/18639	0.21285140562249	1.85043719654738	6.26227912030098e-06	0.000128222731495999
GO:0019003	GDP binding	23/2144	75/18639	0.306666666666667	2.66602611940298	6.78330864235906e-06	0.000136650846682362
GO:0002020	protease binding	34/2144	136/18639	0.25	2.17339085820896	8.46211085036519e-06	0.000167764705588986
GO:0043539	protein serine/threonine kinase activator activity	22/2144	73/18639	0.301369863013699	2.61997802085463	1.45622680116732e-05	0.000284191761665309
GO:0032395	MHC class II receptor activity	7/2144	10/18639	0.7	6.08549440298507	2.30934391309175e-05	0.000441941253791557
GO:0003725	double-stranded RNA binding	22/2144	75/18639	0.293333333333333	2.55011194029851	2.335318074479e-05	0.000441941253791557
GO:0001221	transcription coregulator binding	29/2144	115/18639	0.252173913043478	2.1922899091499	3.18393373665045e-05	0.000593542274190509
GO:0043175	RNA polymerase core enzyme binding	15/2144	42/18639	0.357142857142857	3.10484408315565	3.68812712934869e-05	0.000677422174199487
GO:0004197	cysteine-type endopeptidase activity	24/2144	88/18639	0.272727272727273	2.37097184531886	3.83694460415433e-05	0.000694542581244747
GO:0043021	ribonucleoprotein complex binding	39/2144	177/18639	0.220338983050847	1.91553092587908	4.49762546956933e-05	0.000802504887356014
GO:0046332	SMAD binding	22/2144	79/18639	0.278481012658228	2.42099234838466	5.63613187043221e-05	0.000991482916361948
GO:0031625	ubiquitin protein ligase binding	58/2144	302/18639	0.19205298013245	1.66962476524661	5.79651296978245e-05	0.00100553398600809
GO:0003925	G protein activity	17/2144	54/18639	0.314814814814815	2.73686256218906	7.27458329221878e-05	0.00124465130575086
GO:0000993	RNA polymerase II complex binding	13/2144	36/18639	0.361111111111111	3.13934235074627	0.000106275503950335	0.00179375816802659
GO:0035591	signaling adaptor activity	30/2144	129/18639	0.232558139534884	2.0217589378688	0.000118072733061645	0.00196630458125327
GO:0061659	ubiquitin-like protein ligase activity	67/2144	372/18639	0.18010752688172	1.56577620967742	0.000125465285347764	0.00206192291314943
GO:0019888	protein phosphatase regulator activity	26/2144	107/18639	0.242990654205607	2.11245466592272	0.000154212452762782	0.00250144614935994
GO:0031072	heat shock protein binding	30/2144	131/18639	0.229007633587786	1.99089238919904	0.000158288510849605	0.00253464551347637
GO:0035064	methylated histone binding	20/2144	74/18639	0.27027027027027	2.34961173860428	0.000188949481116602	0.00298731521410932
GO:0044389	ubiquitin-like protein ligase binding	59/2144	322/18639	0.183229813664596	1.59292000787986	0.000193069160762254	0.00301429227240069
GO:0035325	Toll-like receptor binding	7/2144	13/18639	0.538461538461538	4.68114954075775	0.000241027491592691	0.0036892440797428
GO:0000287	magnesium ion binding	45/2144	230/18639	0.195652173913043	1.70091458468527	0.000242208178173667	0.0036892440797428
GO:0035091	phosphatidylinositol binding	53/2144	284/18639	0.186619718309859	1.62239035894471	0.000250347517328096	0.00371821457624828
GO:0004709	MAP kinase kinase kinase activity	10/2144	25/18639	0.4	3.47742537313433	0.000253041024004086	0.00371821457624828
GO:0042974	nuclear retinoic acid receptor binding	10/2144	25/18639	0.4	3.47742537313433	0.000253041024004086	0.00371821457624828
GO:0001222	transcription corepressor binding	15/2144	49/18639	0.306122448979592	2.66129492841913	0.000269861709615089	0.00391927064313076
GO:0140034	methylation-dependent protein binding	20/2144	76/18639	0.263157894736842	2.28777985074627	0.000279026113115974	0.00400578868140059
GO:0019208	phosphatase regulator activity	27/2144	117/18639	0.230769230769231	2.00620694603904	0.000288811641915936	0.00409915614492051
GO:0005543	phospholipid binding	83/2144	497/18639	0.167002012072435	1.45184258536292	0.000295669973117912	0.00414934602723901
GO:0001098	basal transcription machinery binding	17/2144	60/18639	0.283333333333333	2.46317630597015	0.000304866158501339	0.00418301009320669
GO:0001099	basal RNA polymerase II transcription machinery binding	17/2144	60/18639	0.283333333333333	2.46317630597015	0.000304866158501339	0.00418301009320669
GO:0051721	protein phosphatase 2A binding	11/2144	30/18639	0.366666666666667	3.18763992537313	0.000308116035688563	0.00418301009320669
GO:1905394	retromer complex binding	6/2144	10/18639	0.6	5.21613805970149	0.000319987043729402	0.00429746040449487
GO:0005525	GTP binding	66/2144	378/18639	0.174603174603175	1.51792377398721	0.000347324265645257	0.00461497880628645
GO:0003727	single-stranded RNA binding	22/2144	89/18639	0.247191011235955	2.14897073620661	0.000371782893778962	0.00488796667715709
GO:0061630	ubiquitin protein ligase activity	62/2144	353/18639	0.175637393767705	1.52691482389751	0.000440308954020538	0.00571627081685998
GO:0032182	ubiquitin-like protein binding	27/2144	120/18639	0.225	1.95605177238806	0.000443937765600815	0.00571627081685998
GO:0004706	JUN kinase kinase kinase activity	8/2144	18/18639	0.444444444444444	3.86380597014925	0.000455876136207626	0.00581009483799311
GO:0061650	ubiquitin-like protein conjugating enzyme activity	13/2144	41/18639	0.317073170731707	2.75649572260648	0.000466822916706661	0.00588951336329918
GO:1990841	promoter-specific chromatin binding	18/2144	68/18639	0.264705882352941	2.30123737928007	0.00051207969766006	0.00639587542377415
GO:0051087	protein-folding chaperone binding	29/2144	134/18639	0.216417910447761	1.88144283247939	0.000551633807324316	0.00682168935988189
GO:0051059	NF-kappaB binding	11/2144	32/18639	0.34375	2.98841243003731	0.000585391119061872	0.0071681716441988
GO:0004402	histone acetyltransferase activity	13/2144	42/18639	0.30952380952381	2.69086487206823	0.000605656050889608	0.00727133386578071
GO:0019001	guanyl nucleotide binding	68/2144	400/18639	0.17	1.47790578358209	0.000611281069581244	0.00727133386578071
GO:0032561	guanyl ribonucleotide binding	68/2144	400/18639	0.17	1.47790578358209	0.000611281069581244	0.00727133386578071
GO:0002039	p53 binding	18/2144	69/18639	0.260869565217391	2.26788611291369	0.000619391622808985	0.00729830317819266
GO:0000099	sulfur amino acid transmembrane transporter activity	6/2144	11/18639	0.545454545454545	4.74194369063772	0.000635370956989392	0.00741661986242758
GO:0008234	cysteine-type peptidase activity	37/2144	187/18639	0.197860962566845	1.72011682895682	0.000663245130401973	0.00767030710992652
GO:0004857	enzyme inhibitor activity	70/2144	416/18639	0.168269230769231	1.4628592314868	0.000685454859186409	0.00785443228553968
GO:0051219	phosphoprotein binding	22/2144	93/18639	0.236559139784946	2.05654188733751	0.000710742658735503	0.00807015982509676
GO:0140311	protein sequestering activity	11/2144	33/18639	0.333333333333333	2.89785447761194	0.00078768633129597	0.0088632452953934
GO:0048027	mRNA 5'-UTR binding	9/2144	24/18639	0.375	3.26008628731343	0.000900286101340199	0.00995094991658326
GO:0060229	lipase activator activity	9/2144	24/18639	0.375	3.26008628731343	0.000900286101340199	0.00995094991658326
GO:0003779	actin binding	73/2144	443/18639	0.164785553047404	1.43257365823254	0.000971055627984438	0.0106390217487067
GO:0016004	phospholipase activator activity	8/2144	20/18639	0.4	3.47742537313433	0.00106230065395799	0.0113754001032892
GO:0030742	GTP-dependent protein binding	8/2144	20/18639	0.4	3.47742537313433	0.00106230065395799	0.0113754001032892
GO:1901981	phosphatidylinositol phosphate binding	36/2144	185/18639	0.194594594594595	1.69172045179508	0.00106558992160516	0.0113754001032892
GO:0004896	cytokine receptor activity	22/2144	96/18639	0.229166666666667	1.99227495335821	0.00111654649785253	0.0117774452095325
GO:0019210	kinase inhibitor activity	21/2144	90/18639	0.233333333333333	2.02849813432836	0.00112211047232535	0.0117774452095325
GO:0035259	nuclear glucocorticoid receptor binding	6/2144	12/18639	0.5	4.34678171641791	0.00114721234295165	0.0118804103146969
GO:0032813	tumor necrosis factor receptor superfamily binding	14/2144	50/18639	0.28	2.43419776119403	0.00115094447404189	0.0118804103146969
GO:0004715	non-membrane spanning protein tyrosine kinase activity	13/2144	45/18639	0.288888888888889	2.51147388059701	0.0012464170076006	0.0127604495286324
GO:0005516	calmodulin binding	39/2144	207/18639	0.188405797101449	1.63791774821544	0.00128174136856778	0.0130154062548061
GO:0010485	histone H4 acetyltransferase activity	11/2144	35/18639	0.314285714285714	2.73226279317697	0.00136697307925887	0.0135503918729709
GO:0061631	ubiquitin conjugating enzyme activity	11/2144	35/18639	0.314285714285714	2.73226279317697	0.00136697307925887	0.0135503918729709
GO:0140566	histone reader activity	11/2144	35/18639	0.314285714285714	2.73226279317697	0.00136697307925887	0.0135503918729709
GO:0030544	Hsp70 protein binding	14/2144	51/18639	0.274509803921569	2.38646839332748	0.00142096837320382	0.0139747204577289
GO:0072542	protein phosphatase activator activity	8/2144	21/18639	0.380952380952381	3.31183368869936	0.0015443369099429	0.0150693500040522
GO:0070412	R-SMAD binding	9/2144	26/18639	0.346153846153846	3.00931041905855	0.00173835618865957	0.0168310610824481
GO:0001618	virus receptor activity	19/2144	81/18639	0.234567901234568	2.03923092868988	0.00177089584457652	0.0169077487724712
GO:0036041	long-chain fatty acid binding	7/2144	17/18639	0.411764705882353	3.57970258999122	0.00180042480923832	0.0169077487724712
GO:0046965	nuclear retinoid X receptor binding	7/2144	17/18639	0.411764705882353	3.57970258999122	0.00180042480923832	0.0169077487724712
GO:0051787	misfolded protein binding	7/2144	17/18639	0.411764705882353	3.57970258999122	0.00180042480923832	0.0169077487724712
GO:0019955	cytokine binding	29/2144	144/18639	0.201388888888889	1.75078708022388	0.00181621753997279	0.016928773936015
GO:0043022	ribosome binding	24/2144	112/18639	0.214285714285714	1.86290644989339	0.00182997350962448	0.0169306438038591
GO:0004535	poly(A)-specific ribonuclease activity	6/2144	13/18639	0.461538461538462	4.01241389207807	0.00192394221554504	0.0174608362799766
GO:0001784	phosphotyrosine residue binding	13/2144	47/18639	0.276595744680851	2.40460265163544	0.00192921970107027	0.0174608362799766
GO:0061733	protein-lysine-acetyltransferase activity	13/2144	47/18639	0.276595744680851	2.40460265163544	0.00192921970107027	0.0174608362799766
GO:0043130	ubiquitin binding	22/2144	100/18639	0.22	1.91258395522388	0.00195565791001755	0.0175727822274238
GO:0140272	exogenous protein binding	19/2144	82/18639	0.231707317073171	2.01436225882781	0.00206110937589724	0.018388040074969
GO:0005126	cytokine receptor binding	48/2144	275/18639	0.174545454545455	1.51742198100407	0.00209189021320429	0.0185302899027813
GO:0070034	telomerase RNA binding	8/2144	22/18639	0.363636363636364	3.16129579375848	0.00218443693984488	0.0190794527123514
GO:0140517	protein-RNA adaptor activity	8/2144	22/18639	0.363636363636364	3.16129579375848	0.00218443693984488	0.0190794527123514
GO:0045309	protein phosphorylated amino acid binding	15/2144	59/18639	0.254237288135593	2.21022799139894	0.00225690797038182	0.019575542048659
GO:0004713	protein tyrosine kinase activity	28/2144	140/18639	0.2	1.73871268656716	0.0023956482640321	0.0206356184950075
GO:0015631	tubulin binding	63/2144	385/18639	0.163636363636364	1.42258310719132	0.00246125840901643	0.0210555599511063
GO:0015172	acidic amino acid transmembrane transporter activity	7/2144	18/18639	0.388888888888889	3.3808302238806	0.00265604669207604	0.0225673627102243
GO:0031490	chromatin DNA binding	26/2144	128/18639	0.203125	1.76588007229478	0.00268612202974644	0.0225908624819657
GO:0098531	ligand-modulated transcription factor activity	15/2144	60/18639	0.25	2.17339085820896	0.00269498679728814	0.0225908624819657
GO:0004860	protein kinase inhibitor activity	19/2144	84/18639	0.226190476190476	1.96640125266525	0.00276265334484681	0.0230036935180911
GO:0071889	14-3-3 protein binding	10/2144	33/18639	0.303030303030303	2.6344131614654	0.00302821234953822	0.0245611343645372
GO:0005545	1-phosphatidylinositol binding	6/2144	14/18639	0.428571428571429	3.72581289978678	0.00304124724488009	0.0245611343645372
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	5/2144	10/18639	0.5	4.34678171641791	0.00306673174691797	0.0245611343645372
GO:0030957	Tat protein binding	5/2144	10/18639	0.5	4.34678171641791	0.00306673174691797	0.0245611343645372
GO:0099122	RNA polymerase II C-terminal domain binding	5/2144	10/18639	0.5	4.34678171641791	0.00306673174691797	0.0245611343645372
GO:0046966	nuclear thyroid hormone receptor binding	9/2144	28/18639	0.321428571428571	2.79435967484009	0.00310701299407276	0.0245611343645372
GO:0051019	mitogen-activated protein kinase binding	9/2144	28/18639	0.321428571428571	2.79435967484009	0.00310701299407276	0.0245611343645372
GO:0141052	histone H3 demethylase activity	9/2144	28/18639	0.321428571428571	2.79435967484009	0.00310701299407276	0.0245611343645372
GO:0008017	microtubule binding	47/2144	276/18639	0.170289855072464	1.48042565704088	0.00379345508517035	0.0297888265747732
GO:0030145	manganese ion binding	16/2144	68/18639	0.235294117647059	2.04554433713784	0.0038160226196667	0.0297888265747732
GO:0050699	WW domain binding	8/2144	24/18639	0.333333333333333	2.89785447761194	0.00407316192155045	0.0315986288199784
GO:0003743	translation initiation factor activity	13/2144	51/18639	0.254901960784314	2.21600636523266	0.00421983621326846	0.0325344162368661
GO:0004532	RNA exonuclease activity	11/2144	40/18639	0.275	2.39072994402985	0.00441422064008978	0.0336180584114155
GO:0030331	nuclear estrogen receptor binding	11/2144	40/18639	0.275	2.39072994402985	0.00441422064008978	0.0336180584114155
GO:0050700	CARD domain binding	6/2144	15/18639	0.4	3.47742537313433	0.00457976543883124	0.0346674365642437
GO:0042826	histone deacetylase binding	25/2144	127/18639	0.196850393700787	1.7113313844165	0.00492184305663143	0.0370324215526063
GO:0008432	JUN kinase binding	5/2144	11/18639	0.454545454545455	3.9516197421981	0.00509286573852511	0.0374175841612815
GO:0019864	IgG binding	5/2144	11/18639	0.454545454545455	3.9516197421981	0.00509286573852511	0.0374175841612815
GO:0043522	leucine zipper domain binding	5/2144	11/18639	0.454545454545455	3.9516197421981	0.00509286573852511	0.0374175841612815
GO:0140537	transcription regulator activator activity	5/2144	11/18639	0.454545454545455	3.9516197421981	0.00509286573852511	0.0374175841612815
GO:0032452	histone demethylase activity	9/2144	30/18639	0.3	2.60806902985075	0.00520747343390632	0.038035873210228
GO:0008139	nuclear localization sequence binding	8/2144	25/18639	0.32	2.78194029850746	0.0053949503752957	0.0388879582211433
GO:0019211	phosphatase activator activity	8/2144	25/18639	0.32	2.78194029850746	0.0053949503752957	0.0388879582211433
GO:0015175	neutral L-amino acid transmembrane transporter activity	11/2144	41/18639	0.268292682926829	2.3324194575901	0.00541753781463485	0.0388879582211433
GO:0017124	SH3 domain binding	23/2144	115/18639	0.2	1.73871268656716	0.00557501816963192	0.0397897011078301
GO:0008135	translation factor activity, RNA binding	18/2144	83/18639	0.216867469879518	1.8853511059162	0.00563973948846588	0.040022923983488
GO:0034212	protein N-acetyltransferase activity	13/2144	53/18639	0.245283018867925	2.13238348352577	0.0059965213160096	0.042314435727096
GO:0004879	nuclear receptor activity	14/2144	59/18639	0.23728813559322	2.06287945863901	0.00607827163419357	0.0424120741402669
GO:0036002	pre-mRNA binding	14/2144	59/18639	0.23728813559322	2.06287945863901	0.00607827163419357	0.0424120741402669
GO:0180051	translation factor activity	18/2144	84/18639	0.214285714285714	1.86290644989339	0.00642439934581654	0.0445781932384714
GO:0035198	miRNA binding	11/2144	42/18639	0.261904761904762	2.27688566098081	0.00659231607458348	0.0449545935267058
GO:0140457	protein demethylase activity	9/2144	31/18639	0.290322580645161	2.5239377708233	0.00660223574091685	0.0449545935267058
GO:0030275	LRR domain binding	6/2144	16/18639	0.375	3.26008628731343	0.00662261425853793	0.0449545935267058
GO:0140328	floppase activity	6/2144	16/18639	0.375	3.26008628731343	0.00662261425853793	0.0449545935267058
GO:0008143	poly(A) binding	8/2144	26/18639	0.307692307692308	2.67494259471871	0.00702010334713399	0.0473951842192992
GO:0140463	chromatin-protein adaptor activity	13/2144	54/18639	0.240740740740741	2.09289490049751	0.00708455274678933	0.047573152584623
GO:0005078	MAP-kinase scaffold activity	5/2144	12/18639	0.416666666666667	3.62231809701493	0.00791118959250615	0.0520056621107378
GO:0005095	GTPase inhibitor activity	5/2144	12/18639	0.416666666666667	3.62231809701493	0.00791118959250615	0.0520056621107378
GO:0097677	STAT family protein binding	5/2144	12/18639	0.416666666666667	3.62231809701493	0.00791118959250615	0.0520056621107378
GO:1990247	N6-methyladenosine-containing RNA reader activity	5/2144	12/18639	0.416666666666667	3.62231809701493	0.00791118959250615	0.0520056621107378
GO:0060590	ATPase regulator activity	12/2144	49/18639	0.244897959183673	2.1290359427353	0.00823396952472146	0.0538441253213461
GO:0140313	molecular sequestering activity	13/2144	55/18639	0.236363636363636	2.05484226594301	0.00832304940275956	0.0541431703335765
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	8/2144	27/18639	0.296296296296296	2.57587064676617	0.00898878619596764	0.0581137527379001
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	10/2144	38/18639	0.263157894736842	2.28777985074627	0.00907300383017655	0.0581137527379001
GO:0043531	ADP binding	10/2144	38/18639	0.263157894736842	2.28777985074627	0.00907300383017655	0.0581137527379001
GO:0001046	core promoter sequence-specific DNA binding	11/2144	44/18639	0.25	2.17339085820896	0.00953204085895274	0.0607424440450611
GO:0015179	L-amino acid transmembrane transporter activity	14/2144	62/18639	0.225806451612903	1.96306271064035	0.00958119894322398	0.0607457740105926
GO:0019956	chemokine binding	9/2144	33/18639	0.272727272727273	2.37097184531886	0.0102307776447151	0.0645365721123696
GO:0140303	intramembrane lipid transporter activity	11/2144	45/18639	0.244444444444444	2.12509328358209	0.0113361043174593	0.0711497200628474
GO:0005048	signal sequence binding	12/2144	51/18639	0.235294117647059	2.04554433713784	0.0114213634246418	0.0713264145868878
GO:0005035	death receptor activity	5/2144	13/18639	0.384615384615385	3.34367824339839	0.0116532192031069	0.0713474058072573
GO:0017154	semaphorin receptor activity	5/2144	13/18639	0.384615384615385	3.34367824339839	0.0116532192031069	0.0713474058072573
GO:0043560	insulin receptor substrate binding	5/2144	13/18639	0.384615384615385	3.34367824339839	0.0116532192031069	0.0713474058072573
GO:0140333	glycerophospholipid flippase activity	5/2144	13/18639	0.384615384615385	3.34367824339839	0.0116532192031069	0.0713474058072573
GO:0005158	insulin receptor binding	7/2144	23/18639	0.304347826086957	2.64586713173264	0.0122288038871166	0.0745062246585788
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	17/2144	83/18639	0.204819277108434	1.78060937780975	0.0124851312670267	0.0754287546089535
GO:0015291	secondary active transmembrane transporter activity	46/2144	287/18639	0.160278745644599	1.39339344219668	0.0125010025652949	0.0754287546089535
GO:0004722	protein serine/threonine phosphatase activity	20/2144	103/18639	0.194174757281553	1.68807056948268	0.0128562147632492	0.0771990973043187
GO:0061980	regulatory RNA binding	13/2144	58/18639	0.224137931034483	1.94855732115286	0.0130779300405743	0.0781547111037192
GO:0010484	histone H3 acetyltransferase activity	8/2144	29/18639	0.275862068965517	2.39822439526505	0.0141184113078998	0.0839709320169847
GO:0000175	3'-5'-RNA exonuclease activity	9/2144	35/18639	0.257142857142857	2.23548773987207	0.0151833802028958	0.0894530277047965
GO:0005154	epidermal growth factor receptor binding	9/2144	35/18639	0.257142857142857	2.23548773987207	0.0151833802028958	0.0894530277047965
GO:0015295	solute:proton symporter activity	7/2144	24/18639	0.291666666666667	2.53562266791045	0.0155870094023498	0.090855221487192
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	10/2144	41/18639	0.24390243902439	2.12038132508191	0.0156558349460897	0.090855221487192
GO:0140828	metal cation:monoatomic cation antiporter activity	10/2144	41/18639	0.24390243902439	2.12038132508191	0.0156558349460897	0.090855221487192
GO:0043495	protein-membrane adaptor activity	11/2144	47/18639	0.234042553191489	2.03466378215306	0.0157123521547105	0.090855221487192
GO:0005161	platelet-derived growth factor receptor binding	5/2144	14/18639	0.357142857142857	3.10484408315565	0.0164376480687884	0.093747134419711
GO:0019763	immunoglobulin receptor activity	5/2144	14/18639	0.357142857142857	3.10484408315565	0.0164376480687884	0.093747134419711
GO:0032454	histone H3K9 demethylase activity	5/2144	14/18639	0.357142857142857	3.10484408315565	0.0164376480687884	0.093747134419711
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	13/2144	60/18639	0.216666666666667	1.88360541044776	0.0172545125769647	0.0967905432539392
GO:0035925	mRNA 3'-UTR AU-rich region binding	8/2144	30/18639	0.266666666666667	2.31828358208955	0.0173587523529883	0.0967905432539392
GO:0043995	histone H4K5 acetyltransferase activity	8/2144	30/18639	0.266666666666667	2.31828358208955	0.0173587523529883	0.0967905432539392
GO:0043996	histone H4K8 acetyltransferase activity	8/2144	30/18639	0.266666666666667	2.31828358208955	0.0173587523529883	0.0967905432539392
GO:0043997	histone H4K12 acetyltransferase activity	8/2144	30/18639	0.266666666666667	2.31828358208955	0.0173587523529883	0.0967905432539392
GO:0001217	DNA-binding transcription repressor activity	44/2144	278/18639	0.158273381294964	1.37595968001718	0.0175659431605016	0.0975105022554068
GO:0019783	ubiquitin-like protein peptidase activity	23/2144	127/18639	0.181102362204724	1.57442487366318	0.018111289864405	0.100092924958592
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	7/2144	25/18639	0.28	2.43419776119403	0.0195505879128707	0.10757129648976
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	23/2144	128/18639	0.1796875	1.56212467933769	0.019750360617266	0.108193861451602
GO:0005031	tumor necrosis factor receptor activity	4/2144	10/18639	0.4	3.47742537313433	0.0207045121813336	0.108891855600186
GO:0005381	iron ion transmembrane transporter activity	4/2144	10/18639	0.4	3.47742537313433	0.0207045121813336	0.108891855600186
GO:0043422	protein kinase B binding	4/2144	10/18639	0.4	3.47742537313433	0.0207045121813336	0.108891855600186
GO:0070513	death domain binding	4/2144	10/18639	0.4	3.47742537313433	0.0207045121813336	0.108891855600186
GO:0033192	calmodulin-dependent protein phosphatase activity	16/2144	81/18639	0.197530864197531	1.71724709784411	0.0209239754556001	0.108891855600186
GO:0140791	histone H2AXS140 phosphatase activity	16/2144	81/18639	0.197530864197531	1.71724709784411	0.0209239754556001	0.108891855600186
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	16/2144	81/18639	0.197530864197531	1.71724709784411	0.0209239754556001	0.108891855600186
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	16/2144	81/18639	0.197530864197531	1.71724709784411	0.0209239754556001	0.108891855600186
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	16/2144	81/18639	0.197530864197531	1.71724709784411	0.0209239754556001	0.108891855600186
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	16/2144	81/18639	0.197530864197531	1.71724709784411	0.0209239754556001	0.108891855600186
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	16/2144	81/18639	0.197530864197531	1.71724709784411	0.0209239754556001	0.108891855600186
GO:1990439	MAP kinase serine/threonine phosphatase activity	16/2144	81/18639	0.197530864197531	1.71724709784411	0.0209239754556001	0.108891855600186
GO:0004843	cysteine-type deubiquitinase activity	20/2144	108/18639	0.185185185185185	1.60991915422886	0.0210242765538136	0.108906187859704
GO:0035401	histone H3Y41 kinase activity	21/2144	115/18639	0.182608695652174	1.58752027903958	0.0212755082768356	0.108906187859704
GO:0101005	deubiquitinase activity	21/2144	115/18639	0.182608695652174	1.58752027903958	0.0212755082768356	0.108906187859704
GO:0140801	histone H2AXY142 kinase activity	21/2144	115/18639	0.182608695652174	1.58752027903958	0.0212755082768356	0.108906187859704
GO:0004712	protein serine/threonine/tyrosine kinase activity	10/2144	43/18639	0.232558139534884	2.0217589378688	0.0216793425584029	0.110071133558721
GO:0048156	tau protein binding	10/2144	43/18639	0.232558139534884	2.0217589378688	0.0216793425584029	0.110071133558721
GO:0005402	carbohydrate:monoatomic cation symporter activity	5/2144	15/18639	0.333333333333333	2.89785447761194	0.022366589383767	0.112192249559538
GO:0042809	nuclear vitamin D receptor binding	5/2144	15/18639	0.333333333333333	2.89785447761194	0.022366589383767	0.112192249559538
GO:0061578	K63-linked deubiquitinase activity	5/2144	15/18639	0.333333333333333	2.89785447761194	0.022366589383767	0.112192249559538
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	16/2144	82/18639	0.195121951219512	1.69630506006553	0.0233096511850989	0.115991053108321
GO:0033549	MAP kinase phosphatase activity	16/2144	82/18639	0.195121951219512	1.69630506006553	0.0233096511850989	0.115991053108321
GO:0008080	N-acetyltransferase activity	14/2144	69/18639	0.202898550724638	1.76391142115509	0.0238352341868105	0.118135744044946
GO:0008157	protein phosphatase 1 binding	7/2144	26/18639	0.269230769230769	2.34057477037887	0.0241670822265633	0.118837345279439
GO:0019865	immunoglobulin binding	7/2144	26/18639	0.269230769230769	2.34057477037887	0.0241670822265633	0.118837345279439
GO:0001223	transcription coactivator binding	10/2144	44/18639	0.227272727272727	1.97580987109905	0.0252520783523589	0.123335357914723
GO:1990782	protein tyrosine kinase binding	21/2144	117/18639	0.179487179487179	1.56038318025258	0.0253709256969321	0.123335357914723
GO:0070717	poly-purine tract binding	8/2144	32/18639	0.25	2.17339085820896	0.0253780520288901	0.123335357914723
GO:0097110	scaffold protein binding	14/2144	70/18639	0.2	1.73871268656716	0.0267441323350725	0.128210962087743
GO:0016504	peptidase activator activity	12/2144	57/18639	0.210526315789474	1.83022388059702	0.0267512535108183	0.128210962087743
GO:0015293	symporter activity	25/2144	146/18639	0.171232876712329	1.48862387548559	0.0270620662912752	0.128210962087743
GO:0005123	death receptor binding	6/2144	21/18639	0.285714285714286	2.48387526652452	0.0271823211819909	0.128210962087743
GO:0009931	calcium-dependent protein serine/threonine kinase activity	6/2144	21/18639	0.285714285714286	2.48387526652452	0.0271823211819909	0.128210962087743
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	6/2144	21/18639	0.285714285714286	2.48387526652452	0.0271823211819909	0.128210962087743
GO:0051010	microtubule plus-end binding	6/2144	21/18639	0.285714285714286	2.48387526652452	0.0271823211819909	0.128210962087743
GO:0070851	growth factor receptor binding	24/2144	139/18639	0.172661870503597	1.50104692365511	0.0273051368417452	0.128210962087743
GO:0140767	enzyme-substrate adaptor activity	24/2144	139/18639	0.172661870503597	1.50104692365511	0.0273051368417452	0.128210962087743
GO:0017018	myosin phosphatase activity	16/2144	84/18639	0.19047619047619	1.65591684434968	0.0286879481647944	0.133101405770643
GO:0016887	ATP hydrolysis activity	61/2144	417/18639	0.146282973621103	1.27172031031891	0.0287925221803881	0.133101405770643
GO:0001671	ATPase activator activity	7/2144	27/18639	0.259259259259259	2.2538868159204	0.0294794858372717	0.133101405770643
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	5/2144	16/18639	0.3125	2.71673857276119	0.0295229417134165	0.133101405770643
GO:0015385	sodium:proton antiporter activity	5/2144	16/18639	0.3125	2.71673857276119	0.0295229417134165	0.133101405770643
GO:0022858	alanine transmembrane transporter activity	5/2144	16/18639	0.3125	2.71673857276119	0.0295229417134165	0.133101405770643
GO:0140327	flippase activity	5/2144	16/18639	0.3125	2.71673857276119	0.0295229417134165	0.133101405770643
GO:0015173	aromatic amino acid transmembrane transporter activity	4/2144	11/18639	0.363636363636364	3.16129579375848	0.0296254530057957	0.133101405770643
GO:0042608	T cell receptor binding	4/2144	11/18639	0.363636363636364	3.16129579375848	0.0296254530057957	0.133101405770643
GO:0050786	RAGE receptor binding	4/2144	11/18639	0.363636363636364	3.16129579375848	0.0296254530057957	0.133101405770643
GO:0070990	snRNP binding	4/2144	11/18639	0.363636363636364	3.16129579375848	0.0296254530057957	0.133101405770643
GO:0180030	inositol phosphate kinase activity	4/2144	11/18639	0.363636363636364	3.16129579375848	0.0296254530057957	0.133101405770643
GO:0140416	transcription regulator inhibitor activity	8/2144	33/18639	0.242424242424242	2.10753052917232	0.0302251798318261	0.13530913838692
GO:0046972	histone H4K16 acetyltransferase activity	6/2144	22/18639	0.272727272727273	2.37097184531886	0.0338414043633207	0.150956835892098
GO:0031593	polyubiquitin modification-dependent protein binding	12/2144	59/18639	0.203389830508475	1.76818239311915	0.034214917183858	0.151827040309229
GO:0033293	monocarboxylic acid binding	15/2144	79/18639	0.189873417721519	1.65067660117136	0.0342796039769436	0.151827040309229
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	41/2144	268/18639	0.152985074626866	1.32998545054578	0.0348286303769053	0.152467579318287
GO:0015144	carbohydrate transmembrane transporter activity	9/2144	40/18639	0.225	1.95605177238806	0.0349125121577503	0.152467579318287
GO:0032451	demethylase activity	9/2144	40/18639	0.225	1.95605177238806	0.0349125121577503	0.152467579318287
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	9/2144	40/18639	0.225	1.95605177238806	0.0349125121577503	0.152467579318287
GO:0051082	unfolded protein binding	21/2144	121/18639	0.173553719008264	1.50880026520291	0.0353310524763229	0.153631433772799
GO:0036408	histone H3K14 acetyltransferase activity	7/2144	28/18639	0.25	2.17339085820896	0.0355254826241204	0.153631433772799
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	8/2144	34/18639	0.235294117647059	2.04554433713784	0.0356710294588566	0.153631433772799
GO:0030332	cyclin binding	8/2144	34/18639	0.235294117647059	2.04554433713784	0.0356710294588566	0.153631433772799
GO:0051018	protein kinase A binding	11/2144	53/18639	0.207547169811321	1.80432448606026	0.0363867082264196	0.155640406078076
GO:0140296	general transcription initiation factor binding	11/2144	53/18639	0.207547169811321	1.80432448606026	0.0363867082264196	0.155640406078076
GO:0140789	histone phosphatase activity	23/2144	136/18639	0.169117647058824	1.47023499231782	0.03734658660583	0.159200978398231
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	5/2144	17/18639	0.294117647058824	2.5569304214223	0.0379687926720479	0.15967347490703
GO:0005092	GDP-dissociation inhibitor activity	5/2144	17/18639	0.294117647058824	2.5569304214223	0.0379687926720479	0.15967347490703
GO:0008429	phosphatidylethanolamine binding	5/2144	17/18639	0.294117647058824	2.5569304214223	0.0379687926720479	0.15967347490703
GO:0070403	NAD+ binding	5/2144	17/18639	0.294117647058824	2.5569304214223	0.0379687926720479	0.15967347490703
GO:0005504	fatty acid binding	10/2144	47/18639	0.212765957446809	1.84969434741188	0.038469641123219	0.161236851553358
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	4/2144	12/18639	0.333333333333333	2.89785447761194	0.0404825847124404	0.166873756784944
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	4/2144	12/18639	0.333333333333333	2.89785447761194	0.0404825847124404	0.166873756784944
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	4/2144	12/18639	0.333333333333333	2.89785447761194	0.0404825847124404	0.166873756784944
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	4/2144	12/18639	0.333333333333333	2.89785447761194	0.0404825847124404	0.166873756784944
GO:1990817	poly(A) RNA polymerase activity	4/2144	12/18639	0.333333333333333	2.89785447761194	0.0404825847124404	0.166873756784944
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	11/2144	54/18639	0.203703703703704	1.77091106965174	0.041120794426134	0.16871419176376
GO:0061134	peptidase regulator activity	35/2144	226/18639	0.154867256637168	1.34634831924449	0.0413671496764208	0.16871419176376
GO:0043274	phospholipase binding	6/2144	23/18639	0.260869565217391	2.26788611291369	0.041469381001981	0.16871419176376
GO:0044013	histone H2B acetyltransferase activity	6/2144	23/18639	0.260869565217391	2.26788611291369	0.041469381001981	0.16871419176376
GO:0015294	solute:monoatomic cation symporter activity	20/2144	116/18639	0.172413793103448	1.49889024704066	0.0417143591206635	0.169159852408145
GO:0004629	phospholipase C activity	7/2144	29/18639	0.241379310344828	2.09844634585692	0.0423368234974634	0.17112845484897
GO:0140693	molecular condensate scaffold activity	10/2144	48/18639	0.208333333333333	1.81115904850746	0.043771008177579	0.176354803915472
GO:0005548	phospholipid transporter activity	13/2144	68/18639	0.191176470588235	1.6620047739245	0.0444081526801393	0.178346568159144
GO:0001216	DNA-binding transcription activator activity	69/2144	491/18639	0.140529531568228	1.2217023968751	0.045274159710382	0.181241748327779
GO:0016407	acetyltransferase activity	17/2144	96/18639	0.177083333333333	1.53948519123134	0.0460823902233583	0.183887876642091
GO:0048487	beta-tubulin binding	9/2144	42/18639	0.214285714285714	1.86290644989339	0.0462848893590103	0.184107728692369
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	68/2144	484/18639	0.140495867768595	1.22140973849759	0.0467601712794611	0.185407790247768
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	5/2144	18/18639	0.277777777777778	2.41487873134328	0.0477447414793685	0.188712601606745
GO:0044390	ubiquitin-like protein conjugating enzyme binding	8/2144	36/18639	0.222222222222222	1.93190298507463	0.0484582514293105	0.190928567934413
GO:0001968	fibronectin binding	7/2144	30/18639	0.233333333333333	2.02849813432836	0.0499388451501298	0.193675409648061
GO:0008187	poly-pyrimidine tract binding	7/2144	30/18639	0.233333333333333	2.02849813432836	0.0499388451501298	0.193675409648061
GO:0031624	ubiquitin conjugating enzyme binding	7/2144	30/18639	0.233333333333333	2.02849813432836	0.0499388451501298	0.193675409648061
GO:0019957	C-C chemokine binding	6/2144	24/18639	0.25	2.17339085820896	0.050096838201858	0.193675409648061
GO:0043998	histone H2A acetyltransferase activity	6/2144	24/18639	0.25	2.17339085820896	0.050096838201858	0.193675409648061
GO:0140033	acetylation-dependent protein binding	6/2144	24/18639	0.25	2.17339085820896	0.050096838201858	0.193675409648061
GO:0030165	PDZ domain binding	15/2144	83/18639	0.180722891566265	1.57112592159683	0.0502408588678717	0.193675409648061
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	4/2144	13/18639	0.307692307692308	2.67494259471871	0.0532956360499219	0.20194788280636
GO:0046974	histone H3K9 methyltransferase activity	4/2144	13/18639	0.307692307692308	2.67494259471871	0.0532956360499219	0.20194788280636
GO:0089720	caspase binding	4/2144	13/18639	0.307692307692308	2.67494259471871	0.0532956360499219	0.20194788280636
GO:0097157	pre-mRNA intronic binding	4/2144	13/18639	0.307692307692308	2.67494259471871	0.0532956360499219	0.20194788280636
GO:0140666	annealing activity	4/2144	13/18639	0.307692307692308	2.67494259471871	0.0532956360499219	0.20194788280636
GO:1901682	sulfur compound transmembrane transporter activity	12/2144	63/18639	0.19047619047619	1.65591684434968	0.0533569266021609	0.20194788280636
GO:0003724	RNA helicase activity	14/2144	77/18639	0.181818181818182	1.58064789687924	0.0547922058447341	0.206635290733116
GO:0004527	exonuclease activity	15/2144	84/18639	0.178571428571429	1.55242204157783	0.054926274238106	0.206635290733116
GO:0043394	proteoglycan binding	8/2144	37/18639	0.216216216216216	1.87968939088342	0.0558389742534706	0.209438074602357
GO:0051015	actin filament binding	32/2144	209/18639	0.15311004784689	1.33107191316147	0.0561253696078965	0.20988199592893
GO:0008013	beta-catenin binding	18/2144	106/18639	0.169811320754717	1.47626548859476	0.0582033065920697	0.216259092340968
GO:0005164	tumor necrosis factor receptor binding	7/2144	31/18639	0.225806451612903	1.96306271064035	0.0583501314002452	0.216259092340968
GO:0072349	modified amino acid transmembrane transporter activity	7/2144	31/18639	0.225806451612903	1.96306271064035	0.0583501314002452	0.216259092340968
GO:0042834	peptidoglycan binding	5/2144	19/18639	0.263157894736842	2.28777985074627	0.0588700047702793	0.217540343071239
GO:0120020	cholesterol transfer activity	6/2144	25/18639	0.24	2.0864552238806	0.0597430225036434	0.220115147808409
GO:0004540	RNA nuclease activity	20/2144	121/18639	0.165289256198347	1.43695263352658	0.0605289410114903	0.222354845068681
GO:0008408	3'-5' exonuclease activity	11/2144	58/18639	0.189655172413793	1.64877927174472	0.0642632442091584	0.235380621751434
GO:0008186	ATP-dependent activity, acting on RNA	14/2144	79/18639	0.177215189873418	1.5406314944266	0.0655506556192603	0.239394061018878
GO:0071813	lipoprotein particle binding	7/2144	32/18639	0.21875	1.90171700093284	0.0675823136242247	0.242109687241387
GO:0071814	protein-lipid complex binding	7/2144	32/18639	0.21875	1.90171700093284	0.0675823136242247	0.242109687241387
GO:0120015	sterol transfer activity	7/2144	32/18639	0.21875	1.90171700093284	0.0675823136242247	0.242109687241387
GO:0005313	L-glutamate transmembrane transporter activity	4/2144	14/18639	0.285714285714286	2.48387526652452	0.0680388312423754	0.242109687241387
GO:0008474	palmitoyl-(protein) hydrolase activity	4/2144	14/18639	0.285714285714286	2.48387526652452	0.0680388312423754	0.242109687241387
GO:0034236	protein kinase A catalytic subunit binding	4/2144	14/18639	0.285714285714286	2.48387526652452	0.0680388312423754	0.242109687241387
GO:0044548	S100 protein binding	4/2144	14/18639	0.285714285714286	2.48387526652452	0.0680388312423754	0.242109687241387
GO:0071933	Arp2/3 complex binding	4/2144	14/18639	0.285714285714286	2.48387526652452	0.0680388312423754	0.242109687241387
GO:0098599	palmitoyl hydrolase activity	4/2144	14/18639	0.285714285714286	2.48387526652452	0.0680388312423754	0.242109687241387
GO:0004435	phosphatidylinositol phospholipase C activity	6/2144	26/18639	0.230769230769231	2.00620694603904	0.0704158045867675	0.246356694478635
GO:0005112	Notch binding	6/2144	26/18639	0.230769230769231	2.00620694603904	0.0704158045867675	0.246356694478635
GO:0034237	protein kinase A regulatory subunit binding	6/2144	26/18639	0.230769230769231	2.00620694603904	0.0704158045867675	0.246356694478635
GO:0050681	nuclear androgen receptor binding	6/2144	26/18639	0.230769230769231	2.00620694603904	0.0704158045867675	0.246356694478635
GO:0051139	metal cation:proton antiporter activity	6/2144	26/18639	0.230769230769231	2.00620694603904	0.0704158045867675	0.246356694478635
GO:0052742	phosphatidylinositol kinase activity	6/2144	26/18639	0.230769230769231	2.00620694603904	0.0704158045867675	0.246356694478635
GO:0061608	nuclear import signal receptor activity	5/2144	20/18639	0.25	2.17339085820896	0.0713431656068439	0.248903949281978
GO:0061135	endopeptidase regulator activity	28/2144	184/18639	0.152173913043478	1.32293356586632	0.0745745109838619	0.259452825122127
GO:0030291	protein serine/threonine kinase inhibitor activity	9/2144	46/18639	0.195652173913043	1.70091458468527	0.0757948154561417	0.262809390352883
GO:0042578	phosphoric ester hydrolase activity	51/2144	363/18639	0.140495867768595	1.22140973849759	0.0759601200299366	0.262809390352883
GO:0015101	organic cation transmembrane transporter activity	14/2144	81/18639	0.172839506172839	1.5025912106136	0.0776293168998743	0.267141499616446
GO:0030296	protein tyrosine kinase activator activity	7/2144	33/18639	0.212121212121212	1.84408921302578	0.077640003491409	0.267141499616446
GO:0005319	lipid transporter activity	27/2144	178/18639	0.151685393258427	1.31868658812678	0.0812195556511132	0.278690178594067
GO:0071949	FAD binding	8/2144	40/18639	0.2	1.73871268656716	0.0820712559419424	0.280212452669145
GO:0004683	calcium/calmodulin-dependent protein kinase activity	6/2144	27/18639	0.222222222222222	1.93190298507463	0.082111895658052	0.280212452669145
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	15/2144	89/18639	0.168539325842697	1.46520732014087	0.0828358819289424	0.280435018752014
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	15/2144	89/18639	0.168539325842697	1.46520732014087	0.0828358819289424	0.280435018752014
GO:0004518	nuclease activity	31/2144	209/18639	0.148325358851675	1.28947591587517	0.082936216143069	0.280435018752014
GO:0140938	histone H3 methyltransferase activity	9/2144	47/18639	0.191489361702128	1.66472491267069	0.0846349883244655	0.280435018752014
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	4/2144	15/18639	0.266666666666667	2.31828358208955	0.0846469191909602	0.280435018752014
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	4/2144	15/18639	0.266666666666667	2.31828358208955	0.0846469191909602	0.280435018752014
GO:0005041	low-density lipoprotein particle receptor activity	4/2144	15/18639	0.266666666666667	2.31828358208955	0.0846469191909602	0.280435018752014
GO:0015556	C4-dicarboxylate transmembrane transporter activity	4/2144	15/18639	0.266666666666667	2.31828358208955	0.0846469191909602	0.280435018752014
GO:0034483	heparan sulfate sulfotransferase activity	4/2144	15/18639	0.266666666666667	2.31828358208955	0.0846469191909602	0.280435018752014
GO:0047372	monoacylglycerol lipase activity	4/2144	15/18639	0.266666666666667	2.31828358208955	0.0846469191909602	0.280435018752014
GO:0120283	protein serine/threonine kinase binding	4/2144	15/18639	0.266666666666667	2.31828358208955	0.0846469191909602	0.280435018752014
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	5/2144	21/18639	0.238095238095238	2.0698960554371	0.0851434294896106	0.281333712784454
GO:0140793	histone H2AXY142 phosphatase activity	15/2144	90/18639	0.166666666666667	1.44892723880597	0.0893433434419945	0.294432284852378
GO:0001540	amyloid-beta binding	14/2144	83/18639	0.168674698795181	1.46638419349038	0.0910589657270575	0.299296442613407
GO:0042169	SH2 domain binding	8/2144	41/18639	0.195121951219512	1.69630506006553	0.0921907234130728	0.302221032921071
GO:0015297	antiporter activity	21/2144	135/18639	0.155555555555556	1.35233208955224	0.092824061364779	0.303123712472095
GO:0004725	protein tyrosine phosphatase activity	16/2144	98/18639	0.163265306122449	1.41935729515687	0.0939297170966664	0.303123712472095
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	9/2144	48/18639	0.1875	1.63004314365672	0.0940651375891316	0.303123712472095
GO:0038187	pattern recognition receptor activity	9/2144	48/18639	0.1875	1.63004314365672	0.0940651375891316	0.303123712472095
GO:0046875	ephrin receptor binding	6/2144	28/18639	0.214285714285714	1.86290644989339	0.0948172810309424	0.303123712472095
GO:0050698	proteoglycan sulfotransferase activity	6/2144	28/18639	0.214285714285714	1.86290644989339	0.0948172810309424	0.303123712472095
GO:0051119	sugar transmembrane transporter activity	6/2144	28/18639	0.214285714285714	1.86290644989339	0.0948172810309424	0.303123712472095
GO:0051959	dynein light intermediate chain binding	6/2144	28/18639	0.214285714285714	1.86290644989339	0.0948172810309424	0.303123712472095
GO:0000149	SNARE binding	17/2144	106/18639	0.160377358490566	1.39425073922839	0.0980061225360547	0.303123712472095
GO:0051117	ATPase binding	14/2144	84/18639	0.166666666666667	1.44892723880597	0.0982855040248479	0.303123712472095
GO:0004955	prostaglandin receptor activity	3/2144	10/18639	0.3	2.60806902985075	0.0983262808029602	0.303123712472095
GO:0008140	cAMP response element binding protein binding	3/2144	10/18639	0.3	2.60806902985075	0.0983262808029602	0.303123712472095
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	3/2144	10/18639	0.3	2.60806902985075	0.0983262808029602	0.303123712472095
GO:0031419	cobalamin binding	3/2144	10/18639	0.3	2.60806902985075	0.0983262808029602	0.303123712472095
GO:0031996	thioesterase binding	3/2144	10/18639	0.3	2.60806902985075	0.0983262808029602	0.303123712472095
GO:0051864	histone H3K36 demethylase activity	3/2144	10/18639	0.3	2.60806902985075	0.0983262808029602	0.303123712472095
GO:0016779	nucleotidyltransferase activity	21/2144	136/18639	0.154411764705882	1.34238847124671	0.0984485485318923	0.303123712472095
GO:0015377	chloride:monoatomic cation symporter activity	5/2144	22/18639	0.227272727272727	1.97580987109905	0.100232260409107	0.303123712472095
GO:0031683	G-protein beta/gamma-subunit complex binding	5/2144	22/18639	0.227272727272727	1.97580987109905	0.100232260409107	0.303123712472095
GO:0032931	histone H3K56 acetyltransferase activity	5/2144	22/18639	0.227272727272727	1.97580987109905	0.100232260409107	0.303123712472095
GO:0043992	histone H3K9 acetyltransferase activity	5/2144	22/18639	0.227272727272727	1.97580987109905	0.100232260409107	0.303123712472095
GO:0043993	histone H3K18 acetyltransferase activity	5/2144	22/18639	0.227272727272727	1.97580987109905	0.100232260409107	0.303123712472095
GO:0043994	histone H3K23 acetyltransferase activity	5/2144	22/18639	0.227272727272727	1.97580987109905	0.100232260409107	0.303123712472095
GO:0043999	histone H2AK5 acetyltransferase activity	5/2144	22/18639	0.227272727272727	1.97580987109905	0.100232260409107	0.303123712472095
GO:0044012	histone H2AK9 acetyltransferase activity	5/2144	22/18639	0.227272727272727	1.97580987109905	0.100232260409107	0.303123712472095
GO:0044014	histone H2BK5 acetyltransferase activity	5/2144	22/18639	0.227272727272727	1.97580987109905	0.100232260409107	0.303123712472095
GO:0044015	histone H2BK12 acetyltransferase activity	5/2144	22/18639	0.227272727272727	1.97580987109905	0.100232260409107	0.303123712472095
GO:0044016	histone H3K4 acetyltransferase activity	5/2144	22/18639	0.227272727272727	1.97580987109905	0.100232260409107	0.303123712472095
GO:0044017	histone H3K27 acetyltransferase activity	5/2144	22/18639	0.227272727272727	1.97580987109905	0.100232260409107	0.303123712472095
GO:0044018	histone H3K36 acetyltransferase activity	5/2144	22/18639	0.227272727272727	1.97580987109905	0.100232260409107	0.303123712472095
GO:0061133	endopeptidase activator activity	5/2144	22/18639	0.227272727272727	1.97580987109905	0.100232260409107	0.303123712472095
GO:0140908	histone H3K122 acetyltransferase activity	5/2144	22/18639	0.227272727272727	1.97580987109905	0.100232260409107	0.303123712472095
GO:0051879	Hsp90 protein binding	8/2144	42/18639	0.19047619047619	1.65591684434968	0.102992096131676	0.30783241951992
GO:0004708	MAP kinase kinase activity	4/2144	16/18639	0.25	2.17339085820896	0.103021578350141	0.30783241951992
GO:0031435	mitogen-activated protein kinase kinase kinase binding	4/2144	16/18639	0.25	2.17339085820896	0.103021578350141	0.30783241951992
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	4/2144	16/18639	0.25	2.17339085820896	0.103021578350141	0.30783241951992
GO:0070411	I-SMAD binding	4/2144	16/18639	0.25	2.17339085820896	0.103021578350141	0.30783241951992
GO:0004721	phosphoprotein phosphatase activity	26/2144	175/18639	0.148571428571429	1.29161513859275	0.103316970368821	0.307978272054075
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	6/2144	29/18639	0.206896551724138	1.79866829644879	0.108507835170111	0.321152336794949
GO:0051861	glycolipid binding	6/2144	29/18639	0.206896551724138	1.79866829644879	0.108507835170111	0.321152336794949
GO:0106222	lncRNA binding	6/2144	29/18639	0.206896551724138	1.79866829644879	0.108507835170111	0.321152336794949
GO:0061775	cohesin loader activity	23/2144	153/18639	0.150326797385621	1.30687554872695	0.108828310453603	0.321339384767259
GO:0051213	dioxygenase activity	15/2144	93/18639	0.161290322580645	1.40218765045739	0.110753007665106	0.326251194749333
GO:0005484	SNAP receptor activity	7/2144	36/18639	0.194444444444444	1.6904151119403	0.112708876931347	0.330453960768199
GO:0055106	ubiquitin-protein transferase regulator activity	7/2144	36/18639	0.194444444444444	1.6904151119403	0.112708876931347	0.330453960768199
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	14/2144	86/18639	0.162790697674419	1.41523125650816	0.113762792101414	0.332762827481652
GO:0008375	acetylglucosaminyltransferase activity	8/2144	43/18639	0.186046511627907	1.61740715029504	0.114465004427912	0.334034557314165
GO:0003887	DNA-directed DNA polymerase activity	5/2144	23/18639	0.217391304347826	1.88990509409474	0.116555282466643	0.337766932252521
GO:0016493	C-C chemokine receptor activity	5/2144	23/18639	0.217391304347826	1.88990509409474	0.116555282466643	0.337766932252521
GO:0070577	lysine-acetylated histone binding	5/2144	23/18639	0.217391304347826	1.88990509409474	0.116555282466643	0.337766932252521
GO:0016410	N-acyltransferase activity	15/2144	94/18639	0.159574468085106	1.38727076055891	0.118517850392914	0.342646635921435
GO:0004620	phospholipase activity	17/2144	109/18639	0.155963302752294	1.35587686567164	0.11878782494314	0.342646635921435
GO:0008081	phosphoric diester hydrolase activity	14/2144	87/18639	0.160919540229885	1.39896423057128	0.122010578751885	0.345183240406224
GO:0038024	cargo receptor activity	11/2144	65/18639	0.169230769230769	1.47121842709529	0.122033830649652	0.345183240406224
GO:0015171	amino acid transmembrane transporter activity	16/2144	102/18639	0.156862745098039	1.36369622475856	0.122652490826183	0.345183240406224
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	4/2144	17/18639	0.235294117647059	2.04554433713784	0.123037820097247	0.345183240406224
GO:0030169	low-density lipoprotein particle binding	4/2144	17/18639	0.235294117647059	2.04554433713784	0.123037820097247	0.345183240406224
GO:0032183	SUMO binding	4/2144	17/18639	0.235294117647059	2.04554433713784	0.123037820097247	0.345183240406224
GO:0070566	adenylyltransferase activity	6/2144	30/18639	0.2	1.73871268656716	0.123150082675106	0.345183240406224
GO:0004016	adenylate cyclase activity	3/2144	11/18639	0.272727272727273	2.37097184531886	0.124089091226897	0.345183240406224
GO:0004954	prostanoid receptor activity	3/2144	11/18639	0.272727272727273	2.37097184531886	0.124089091226897	0.345183240406224
GO:0005225	volume-sensitive anion channel activity	3/2144	11/18639	0.272727272727273	2.37097184531886	0.124089091226897	0.345183240406224
GO:0010854	adenylate cyclase regulator activity	3/2144	11/18639	0.272727272727273	2.37097184531886	0.124089091226897	0.345183240406224
GO:0032050	clathrin heavy chain binding	3/2144	11/18639	0.272727272727273	2.37097184531886	0.124089091226897	0.345183240406224
GO:0034056	estrogen response element binding	3/2144	11/18639	0.272727272727273	2.37097184531886	0.124089091226897	0.345183240406224
GO:0034713	type I transforming growth factor beta receptor binding	3/2144	11/18639	0.272727272727273	2.37097184531886	0.124089091226897	0.345183240406224
GO:0047676	arachidonate-CoA ligase activity	3/2144	11/18639	0.272727272727273	2.37097184531886	0.124089091226897	0.345183240406224
GO:0140031	phosphorylation-dependent protein binding	3/2144	11/18639	0.272727272727273	2.37097184531886	0.124089091226897	0.345183240406224
GO:0042805	actinin binding	7/2144	37/18639	0.189189189189189	1.64472821702299	0.125978520889518	0.349660383535574
GO:0140713	histone chaperone activity	24/2144	164/18639	0.146341463414634	1.27222879504914	0.128667534809855	0.356332042078734
GO:1902936	phosphatidylinositol bisphosphate binding	17/2144	111/18639	0.153153153153153	1.33144665187576	0.13399344206227	0.367152169050032
GO:0001091	RNA polymerase II general transcription initiation factor binding	5/2144	24/18639	0.208333333333333	1.81115904850746	0.134044346746849	0.367152169050032
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	5/2144	24/18639	0.208333333333333	1.81115904850746	0.134044346746849	0.367152169050032
GO:0030215	semaphorin receptor binding	5/2144	24/18639	0.208333333333333	1.81115904850746	0.134044346746849	0.367152169050032
GO:0070300	phosphatidic acid binding	5/2144	24/18639	0.208333333333333	1.81115904850746	0.134044346746849	0.367152169050032
GO:0005080	protein kinase C binding	9/2144	52/18639	0.173076923076923	1.50465520952928	0.137565784637431	0.375973008779326
GO:0005452	solute:inorganic anion antiporter activity	6/2144	31/18639	0.193548387096774	1.68262518054887	0.138702070981073	0.377426768312331
GO:0070273	phosphatidylinositol-4-phosphate binding	6/2144	31/18639	0.193548387096774	1.68262518054887	0.138702070981073	0.377426768312331
GO:0046915	transition metal ion transmembrane transporter activity	8/2144	45/18639	0.177777777777778	1.5455223880597	0.139362258638729	0.378398828347332
GO:0000900	mRNA regulatory element binding translation repressor activity	4/2144	18/18639	0.222222222222222	1.93190298507463	0.144550128273784	0.388259512102857
GO:0030228	lipoprotein particle receptor activity	4/2144	18/18639	0.222222222222222	1.93190298507463	0.144550128273784	0.388259512102857
GO:0034185	apolipoprotein binding	4/2144	18/18639	0.222222222222222	1.93190298507463	0.144550128273784	0.388259512102857
GO:0050811	GABA receptor binding	4/2144	18/18639	0.222222222222222	1.93190298507463	0.144550128273784	0.388259512102857
GO:0000510	H3-H4 histone complex chaperone activity	22/2144	151/18639	0.145695364238411	1.26661189087674	0.145480745928052	0.388259512102857
GO:0140584	chromatin extrusion motor activity	22/2144	151/18639	0.145695364238411	1.26661189087674	0.145480745928052	0.388259512102857
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	22/2144	151/18639	0.145695364238411	1.26661189087674	0.145480745928052	0.388259512102857
GO:0140849	ATP-dependent H2AZ histone chaperone activity	22/2144	151/18639	0.145695364238411	1.26661189087674	0.145480745928052	0.388259512102857
GO:1901505	carbohydrate derivative transmembrane transporter activity	9/2144	53/18639	0.169811320754717	1.47626548859476	0.149827817168944	0.392850481997
GO:0000340	RNA 7-methylguanosine cap binding	3/2144	12/18639	0.25	2.17339085820896	0.151957926731716	0.392850481997
GO:0004000	adenosine deaminase activity	3/2144	12/18639	0.25	2.17339085820896	0.151957926731716	0.392850481997
GO:0004875	complement receptor activity	3/2144	12/18639	0.25	2.17339085820896	0.151957926731716	0.392850481997
GO:0015132	prostaglandin transmembrane transporter activity	3/2144	12/18639	0.25	2.17339085820896	0.151957926731716	0.392850481997
GO:0015269	calcium-activated potassium channel activity	3/2144	12/18639	0.25	2.17339085820896	0.151957926731716	0.392850481997
GO:0015368	calcium:monoatomic cation antiporter activity	3/2144	12/18639	0.25	2.17339085820896	0.151957926731716	0.392850481997
GO:0016840	carbon-nitrogen lyase activity	3/2144	12/18639	0.25	2.17339085820896	0.151957926731716	0.392850481997
GO:0035014	phosphatidylinositol 3-kinase regulator activity	3/2144	12/18639	0.25	2.17339085820896	0.151957926731716	0.392850481997
GO:0042301	phosphate ion binding	3/2144	12/18639	0.25	2.17339085820896	0.151957926731716	0.392850481997
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	3/2144	12/18639	0.25	2.17339085820896	0.151957926731716	0.392850481997
GO:0070410	co-SMAD binding	3/2144	12/18639	0.25	2.17339085820896	0.151957926731716	0.392850481997
GO:0015296	monoatomic anion:monoatomic cation symporter activity	5/2144	25/18639	0.2	1.73871268656716	0.152619677807651	0.392850481997
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	5/2144	25/18639	0.2	1.73871268656716	0.152619677807651	0.392850481997
GO:0015616	DNA translocase activity	22/2144	152/18639	0.144736842105263	1.25827891791045	0.15264496268359	0.392850481997
GO:0140674	ATP-dependent histone chaperone activity	22/2144	152/18639	0.144736842105263	1.25827891791045	0.15264496268359	0.392850481997
GO:0030276	clathrin binding	8/2144	46/18639	0.173913043478261	1.51192407527579	0.152744878256116	0.392850481997
GO:0003697	single-stranded DNA binding	18/2144	121/18639	0.148760330578512	1.29325737017392	0.152862557446391	0.392850481997
GO:0032934	sterol binding	11/2144	68/18639	0.161764705882353	1.40631173178227	0.153506624812253	0.393695635298776
GO:0043425	bHLH transcription factor binding	6/2144	32/18639	0.1875	1.63004314365672	0.155114322678807	0.397003666036537
GO:0015026	coreceptor activity	10/2144	61/18639	0.163934426229508	1.42517433325177	0.158145104934151	0.403932998083343
GO:0004866	endopeptidase inhibitor activity	23/2144	161/18639	0.142857142857143	1.24193763326226	0.161169276313996	0.410817196155471
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	9/2144	54/18639	0.166666666666667	1.44892723880597	0.162610799521638	0.413445814931973
GO:0016298	lipase activity	19/2144	130/18639	0.146153846153846	1.27059773249139	0.163193584276592	0.413445814931973
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	19/2144	130/18639	0.146153846153846	1.27059773249139	0.163193584276592	0.413445814931973
GO:0016791	phosphatase activity	37/2144	273/18639	0.135531135531136	1.1782485238642	0.164513356494183	0.415945713079422
GO:0022821	solute:potassium antiporter activity	4/2144	19/18639	0.210526315789474	1.83022388059702	0.167398161208052	0.418998603905524
GO:0031420	alkali metal ion binding	4/2144	19/18639	0.210526315789474	1.83022388059702	0.167398161208052	0.418998603905524
GO:0097001	ceramide binding	4/2144	19/18639	0.210526315789474	1.83022388059702	0.167398161208052	0.418998603905524
GO:0140036	ubiquitin-modified protein reader activity	4/2144	19/18639	0.210526315789474	1.83022388059702	0.167398161208052	0.418998603905524
GO:1990380	K48-linked deubiquitinase activity	4/2144	19/18639	0.210526315789474	1.83022388059702	0.167398161208052	0.418998603905524
GO:0140662	ATP-dependent protein folding chaperone	7/2144	40/18639	0.175	1.52137360074627	0.170144244007245	0.424196930354211
GO:0001637	G protein-coupled chemoattractant receptor activity	5/2144	26/18639	0.192307692307692	1.6718391216992	0.172192028574527	0.424196930354211
GO:0004529	DNA exonuclease activity	5/2144	26/18639	0.192307692307692	1.6718391216992	0.172192028574527	0.424196930354211
GO:0004950	chemokine receptor activity	5/2144	26/18639	0.192307692307692	1.6718391216992	0.172192028574527	0.424196930354211
GO:0005160	transforming growth factor beta receptor binding	5/2144	26/18639	0.192307692307692	1.6718391216992	0.172192028574527	0.424196930354211
GO:0005227	calcium-activated cation channel activity	5/2144	26/18639	0.192307692307692	1.6718391216992	0.172192028574527	0.424196930354211
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	5/2144	26/18639	0.192307692307692	1.6718391216992	0.172192028574527	0.424196930354211
GO:0015145	monosaccharide transmembrane transporter activity	5/2144	26/18639	0.192307692307692	1.6718391216992	0.172192028574527	0.424196930354211
GO:0004386	helicase activity	22/2144	155/18639	0.141935483870968	1.2339251324025	0.175292302132629	0.430984420007192
GO:0016278	lysine N-methyltransferase activity	11/2144	70/18639	0.157142857142857	1.36613139658849	0.176567050140366	0.433265708497676
GO:0071714	icosanoid transmembrane transporter activity	3/2144	13/18639	0.230769230769231	2.00620694603904	0.181556613936254	0.442898849231214
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	3/2144	13/18639	0.230769230769231	2.00620694603904	0.181556613936254	0.442898849231214
GO:0140852	histone ubiquitin ligase activity	3/2144	13/18639	0.230769230769231	2.00620694603904	0.181556613936254	0.442898849231214
GO:0140597	protein carrier chaperone	26/2144	188/18639	0.138297872340426	1.20230132581772	0.184877438513011	0.450120703124271
GO:0001727	lipid kinase activity	7/2144	41/18639	0.170731707317073	1.48426692755734	0.186193498247222	0.450689300989885
GO:0042287	MHC protein binding	7/2144	41/18639	0.170731707317073	1.48426692755734	0.186193498247222	0.450689300989885
GO:0140318	protein transporter activity	7/2144	41/18639	0.170731707317073	1.48426692755734	0.186193498247222	0.450689300989885
GO:0022804	active transmembrane transporter activity	59/2144	457/18639	0.12910284463895	1.12236376922826	0.188091660585216	0.454403257390589
GO:0001614	purinergic nucleotide receptor activity	4/2144	20/18639	0.2	1.73871268656716	0.191411910108354	0.457119456453793
GO:0010851	cyclase regulator activity	4/2144	20/18639	0.2	1.73871268656716	0.191411910108354	0.457119456453793
GO:0015095	magnesium ion transmembrane transporter activity	4/2144	20/18639	0.2	1.73871268656716	0.191411910108354	0.457119456453793
GO:0016502	nucleotide receptor activity	4/2144	20/18639	0.2	1.73871268656716	0.191411910108354	0.457119456453793
GO:0042288	MHC class I protein binding	4/2144	20/18639	0.2	1.73871268656716	0.191411910108354	0.457119456453793
GO:0052745	inositol phosphate phosphatase activity	4/2144	20/18639	0.2	1.73871268656716	0.191411910108354	0.457119456453793
GO:0008266	poly(U) RNA binding	5/2144	27/18639	0.185185185185185	1.60991915422886	0.192664786055545	0.459233430884304
GO:0016763	pentosyltransferase activity	8/2144	49/18639	0.163265306122449	1.41935729515687	0.196302840563064	0.467013805453843
GO:0140658	ATP-dependent chromatin remodeler activity	22/2144	158/18639	0.139240506329114	1.21049617419233	0.199603730489164	0.473905402078098
GO:0003823	antigen binding	24/2144	174/18639	0.137931034482759	1.19911219763253	0.199958484303569	0.473905402078098
GO:0019894	kinesin binding	7/2144	42/18639	0.166666666666667	1.44892723880597	0.202833778670332	0.479809449922811
GO:0034061	DNA polymerase activity	6/2144	35/18639	0.171428571428571	1.49032515991471	0.208926208765561	0.492066564575758
GO:0043015	gamma-tubulin binding	6/2144	35/18639	0.171428571428571	1.49032515991471	0.208926208765561	0.492066564575758
GO:0019843	rRNA binding	10/2144	65/18639	0.153846153846154	1.33747129735936	0.209591202845719	0.492066564575758
GO:0120013	lipid transfer activity	10/2144	65/18639	0.153846153846154	1.33747129735936	0.209591202845719	0.492066564575758
GO:0004705	JUN kinase activity	3/2144	14/18639	0.214285714285714	1.86290644989339	0.212516009216403	0.494287701138337
GO:0008174	mRNA methyltransferase activity	3/2144	14/18639	0.214285714285714	1.86290644989339	0.212516009216403	0.494287701138337
GO:0015386	potassium:proton antiporter activity	3/2144	14/18639	0.214285714285714	1.86290644989339	0.212516009216403	0.494287701138337
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	3/2144	14/18639	0.214285714285714	1.86290644989339	0.212516009216403	0.494287701138337
GO:1901474	azole transmembrane transporter activity	3/2144	14/18639	0.214285714285714	1.86290644989339	0.212516009216403	0.494287701138337
GO:0046625	sphingolipid binding	5/2144	28/18639	0.178571428571429	1.55242204157783	0.213935982800024	0.495744049197086
GO:0097718	disordered domain specific binding	5/2144	28/18639	0.178571428571429	1.55242204157783	0.213935982800024	0.495744049197086
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	4/2144	21/18639	0.19047619047619	1.65591684434968	0.216416258489235	0.499051904839179
GO:0035613	RNA stem-loop binding	4/2144	21/18639	0.19047619047619	1.65591684434968	0.216416258489235	0.499051904839179
GO:0003689	DNA clamp loader activity	22/2144	160/18639	0.1375	1.19536497201493	0.216682230794397	0.499051904839179
GO:0140104	molecular carrier activity	33/2144	249/18639	0.132530120481928	1.15215900917101	0.21716600219535	0.499051904839179
GO:0030971	receptor tyrosine kinase binding	12/2144	81/18639	0.148148148148148	1.28793532338308	0.217361278008418	0.499051904839179
GO:0030414	peptidase inhibitor activity	23/2144	169/18639	0.136094674556213	1.18314768612559	0.225070220984317	0.5158031302925
GO:0004869	cysteine-type endopeptidase inhibitor activity	6/2144	36/18639	0.166666666666667	1.44892723880597	0.228169675132404	0.521948579194821
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	17/2144	122/18639	0.139344262295082	1.21139818326401	0.235542175034254	0.535707863815326
GO:0003785	actin monomer binding	5/2144	29/18639	0.172413793103448	1.49889024704066	0.235900180222922	0.535707863815326
GO:0005416	amino acid:monoatomic cation symporter activity	5/2144	29/18639	0.172413793103448	1.49889024704066	0.235900180222922	0.535707863815326
GO:0043236	laminin binding	5/2144	29/18639	0.172413793103448	1.49889024704066	0.235900180222922	0.535707863815326
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	10/2144	67/18639	0.149253731343284	1.29754678102027	0.237612935725692	0.537818968529175
GO:0019205	nucleobase-containing compound kinase activity	7/2144	44/18639	0.159090909090909	1.38306690976934	0.237691009309932	0.537818968529175
GO:0004407	histone deacetylase activity	4/2144	22/18639	0.181818181818182	1.58064789687924	0.242234924729263	0.539504626981859
GO:0008970	phospholipase A1 activity	4/2144	22/18639	0.181818181818182	1.58064789687924	0.242234924729263	0.539504626981859
GO:0033558	protein lysine deacetylase activity	4/2144	22/18639	0.181818181818182	1.58064789687924	0.242234924729263	0.539504626981859
GO:0033691	sialic acid binding	4/2144	22/18639	0.181818181818182	1.58064789687924	0.242234924729263	0.539504626981859
GO:0140035	ubiquitin-like protein reader activity	4/2144	22/18639	0.181818181818182	1.58064789687924	0.242234924729263	0.539504626981859
GO:0008514	organic anion transmembrane transporter activity	35/2144	269/18639	0.130111524163569	1.13113278865894	0.242721179909291	0.539504626981859
GO:0030159	signaling receptor complex adaptor activity	8/2144	52/18639	0.153846153846154	1.33747129735936	0.244267282138938	0.539504626981859
GO:0000774	adenyl-nucleotide exchange factor activity	3/2144	15/18639	0.2	1.73871268656716	0.244483281722764	0.539504626981859
GO:0004467	long-chain fatty acid-CoA ligase activity	3/2144	15/18639	0.2	1.73871268656716	0.244483281722764	0.539504626981859
GO:0004953	icosanoid receptor activity	3/2144	15/18639	0.2	1.73871268656716	0.244483281722764	0.539504626981859
GO:0050780	dopamine receptor binding	3/2144	15/18639	0.2	1.73871268656716	0.244483281722764	0.539504626981859
GO:0055105	ubiquitin-protein transferase inhibitor activity	3/2144	15/18639	0.2	1.73871268656716	0.244483281722764	0.539504626981859
GO:0141050	histone H3K deacetylase activity	3/2144	15/18639	0.2	1.73871268656716	0.244483281722764	0.539504626981859
GO:0141051	histone H4K deacetylase activity	3/2144	15/18639	0.2	1.73871268656716	0.244483281722764	0.539504626981859
GO:0070001	aspartic-type peptidase activity	6/2144	37/18639	0.162162162162162	1.40976704316257	0.247948608211672	0.546186616677916
GO:0046982	protein heterodimerization activity	47/2144	369/18639	0.127371273712737	1.10731024754277	0.248417794326703	0.546256734355726
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	9/2144	60/18639	0.15	1.30403451492537	0.248878410231894	0.546307793285827
GO:0015081	sodium ion transmembrane transporter activity	22/2144	164/18639	0.134146341463415	1.16620972879505	0.252749691984637	0.553832219804933
GO:0008009	chemokine activity	7/2144	45/18639	0.155555555555556	1.35233208955224	0.255804200223048	0.559543688403829
GO:0043178	alcohol binding	13/2144	92/18639	0.141304347826087	1.22843831116158	0.256764752038381	0.560662893874018
GO:0001965	G-protein alpha-subunit binding	5/2144	30/18639	0.166666666666667	1.44892723880597	0.258450199732485	0.562376828337759
GO:0022839	monoatomic ion-gated channel activity	5/2144	30/18639	0.166666666666667	1.44892723880597	0.258450199732485	0.562376828337759
GO:0004864	protein phosphatase inhibitor activity	8/2144	53/18639	0.150943396226415	1.31223598986201	0.261056520355826	0.566075683896573
GO:0008146	sulfotransferase activity	8/2144	53/18639	0.150943396226415	1.31223598986201	0.261056520355826	0.566075683896573
GO:0019905	syntaxin binding	9/2144	61/18639	0.147540983606557	1.2826568999266	0.264582251533427	0.572693775057857
GO:0016279	protein-lysine N-methyltransferase activity	10/2144	69/18639	0.144927536231884	1.2599367293965	0.266906632094443	0.572693775057857
GO:0042162	telomeric DNA binding	6/2144	38/18639	0.157894736842105	1.37266791044776	0.268189531744813	0.572693775057857
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	4/2144	23/18639	0.173913043478261	1.51192407527579	0.268693796784551	0.572693775057857
GO:0005283	amino acid:sodium symporter activity	4/2144	23/18639	0.173913043478261	1.51192407527579	0.268693796784551	0.572693775057857
GO:0016849	phosphorus-oxygen lyase activity	4/2144	23/18639	0.173913043478261	1.51192407527579	0.268693796784551	0.572693775057857
GO:0042171	lysophosphatidic acid acyltransferase activity	4/2144	23/18639	0.173913043478261	1.51192407527579	0.268693796784551	0.572693775057857
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	4/2144	23/18639	0.173913043478261	1.51192407527579	0.268693796784551	0.572693775057857
GO:0071617	lysophospholipid acyltransferase activity	4/2144	23/18639	0.173913043478261	1.51192407527579	0.268693796784551	0.572693775057857
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	4/2144	23/18639	0.173913043478261	1.51192407527579	0.268693796784551	0.572693775057857
GO:0000062	fatty-acyl-CoA binding	3/2144	16/18639	0.1875	1.63004314365672	0.277128290193369	0.578109345406165
GO:0004707	MAP kinase activity	3/2144	16/18639	0.1875	1.63004314365672	0.277128290193369	0.578109345406165
GO:0005149	interleukin-1 receptor binding	3/2144	16/18639	0.1875	1.63004314365672	0.277128290193369	0.578109345406165
GO:0008142	oxysterol binding	3/2144	16/18639	0.1875	1.63004314365672	0.277128290193369	0.578109345406165
GO:0008296	3'-5'-DNA exonuclease activity	3/2144	16/18639	0.1875	1.63004314365672	0.277128290193369	0.578109345406165
GO:0015378	sodium:chloride symporter activity	3/2144	16/18639	0.1875	1.63004314365672	0.277128290193369	0.578109345406165
GO:0015923	mannosidase activity	3/2144	16/18639	0.1875	1.63004314365672	0.277128290193369	0.578109345406165
GO:0034450	ubiquitin-ubiquitin ligase activity	3/2144	16/18639	0.1875	1.63004314365672	0.277128290193369	0.578109345406165
GO:0043023	ribosomal large subunit binding	3/2144	16/18639	0.1875	1.63004314365672	0.277128290193369	0.578109345406165
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	3/2144	16/18639	0.1875	1.63004314365672	0.277128290193369	0.578109345406165
GO:0055102	lipase inhibitor activity	3/2144	16/18639	0.1875	1.63004314365672	0.277128290193369	0.578109345406165
GO:0097027	ubiquitin-protein transferase activator activity	3/2144	16/18639	0.1875	1.63004314365672	0.277128290193369	0.578109345406165
GO:0015485	cholesterol binding	8/2144	54/18639	0.148148148148148	1.28793532338308	0.278177515283511	0.578109345406165
GO:0017069	snRNA binding	8/2144	54/18639	0.148148148148148	1.28793532338308	0.278177515283511	0.578109345406165
GO:0051287	NAD binding	8/2144	54/18639	0.148148148148148	1.28793532338308	0.278177515283511	0.578109345406165
GO:0016411	acylglycerol O-acyltransferase activity	5/2144	31/18639	0.161290322580645	1.40218765045739	0.281478686030833	0.583998137628756
GO:0016209	antioxidant activity	12/2144	86/18639	0.13953488372093	1.21305536272128	0.282736967076926	0.585635940097979
GO:0016776	phosphotransferase activity, phosphate group as acceptor	6/2144	39/18639	0.153846153846154	1.33747129735936	0.28881827004463	0.596254577331807
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	6/2144	39/18639	0.153846153846154	1.33747129735936	0.28881827004463	0.596254577331807
GO:0061749	forked DNA-dependent helicase activity	7/2144	47/18639	0.148936170212766	1.29478604318831	0.293129557907612	0.597465994827382
GO:1990518	single-stranded 3'-5' DNA helicase activity	7/2144	47/18639	0.148936170212766	1.29478604318831	0.293129557907612	0.597465994827382
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	4/2144	24/18639	0.166666666666667	1.44892723880597	0.295623686792092	0.597465994827382
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	4/2144	24/18639	0.166666666666667	1.44892723880597	0.295623686792092	0.597465994827382
GO:0004622	lysophospholipase activity	4/2144	24/18639	0.166666666666667	1.44892723880597	0.295623686792092	0.597465994827382
GO:0005315	phosphate transmembrane transporter activity	4/2144	24/18639	0.166666666666667	1.44892723880597	0.295623686792092	0.597465994827382
GO:0015149	hexose transmembrane transporter activity	4/2144	24/18639	0.166666666666667	1.44892723880597	0.295623686792092	0.597465994827382
GO:0030552	cAMP binding	4/2144	24/18639	0.166666666666667	1.44892723880597	0.295623686792092	0.597465994827382
GO:0042625	ATPase-coupled ion transmembrane transporter activity	4/2144	24/18639	0.166666666666667	1.44892723880597	0.295623686792092	0.597465994827382
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	4/2144	24/18639	0.166666666666667	1.44892723880597	0.295623686792092	0.597465994827382
GO:0046961	proton-transporting ATPase activity, rotational mechanism	4/2144	24/18639	0.166666666666667	1.44892723880597	0.295623686792092	0.597465994827382
GO:0055056	D-glucose transmembrane transporter activity	4/2144	24/18639	0.166666666666667	1.44892723880597	0.295623686792092	0.597465994827382
GO:0070840	dynein complex binding	4/2144	24/18639	0.166666666666667	1.44892723880597	0.295623686792092	0.597465994827382
GO:0015370	solute:sodium symporter activity	11/2144	79/18639	0.139240506329114	1.21049617419233	0.29708947733224	0.599458412258429
GO:0022884	macromolecule transmembrane transporter activity	5/2144	32/18639	0.15625	1.3583692863806	0.304879494058987	0.605488467736024
GO:0030515	snoRNA binding	5/2144	32/18639	0.15625	1.3583692863806	0.304879494058987	0.605488467736024
GO:0140142	nucleocytoplasmic carrier activity	5/2144	32/18639	0.15625	1.3583692863806	0.304879494058987	0.605488467736024
GO:0140097	catalytic activity, acting on DNA	42/2144	336/18639	0.125	1.08669542910448	0.305743148557762	0.605488467736024
GO:0015036	disulfide oxidoreductase activity	6/2144	40/18639	0.15	1.30403451492537	0.309760745227698	0.605488467736024
GO:0061791	GTPase motor activity	6/2144	40/18639	0.15	1.30403451492537	0.309760745227698	0.605488467736024
GO:1990606	membrane scission GTPase motor activity	6/2144	40/18639	0.15	1.30403451492537	0.309760745227698	0.605488467736024
GO:0140098	catalytic activity, acting on RNA	48/2144	387/18639	0.124031007751938	1.07827143353002	0.31008632744365	0.605488467736024
GO:0004029	aldehyde dehydrogenase (NAD+) activity	3/2144	17/18639	0.176470588235294	1.53415825285338	0.310147676642538	0.605488467736024
GO:0004659	prenyltransferase activity	3/2144	17/18639	0.176470588235294	1.53415825285338	0.310147676642538	0.605488467736024
GO:0008484	sulfuric ester hydrolase activity	3/2144	17/18639	0.176470588235294	1.53415825285338	0.310147676642538	0.605488467736024
GO:0015278	intracellularly gated calcium channel activity	3/2144	17/18639	0.176470588235294	1.53415825285338	0.310147676642538	0.605488467736024
GO:0015347	sodium-independent organic anion transmembrane transporter activity	3/2144	17/18639	0.176470588235294	1.53415825285338	0.310147676642538	0.605488467736024
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	3/2144	17/18639	0.176470588235294	1.53415825285338	0.310147676642538	0.605488467736024
GO:0038191	neuropilin binding	3/2144	17/18639	0.176470588235294	1.53415825285338	0.310147676642538	0.605488467736024
GO:0048038	quinone binding	3/2144	17/18639	0.176470588235294	1.53415825285338	0.310147676642538	0.605488467736024
GO:1901567	fatty acid derivative binding	3/2144	17/18639	0.176470588235294	1.53415825285338	0.310147676642538	0.605488467736024
GO:0009378	four-way junction helicase activity	7/2144	48/18639	0.145833333333333	1.26781133395522	0.312231571104007	0.605488467736024
GO:0036121	double-stranded DNA helicase activity	7/2144	48/18639	0.145833333333333	1.26781133395522	0.312231571104007	0.605488467736024
GO:0043138	3'-5' DNA helicase activity	7/2144	48/18639	0.145833333333333	1.26781133395522	0.312231571104007	0.605488467736024
GO:0042379	chemokine receptor binding	10/2144	72/18639	0.138888888888889	1.20743936567164	0.312755268836119	0.605488467736024
GO:0019212	phosphatase inhibitor activity	8/2144	56/18639	0.142857142857143	1.24193763326226	0.313243836048463	0.605488467736024
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	29/2144	229/18639	0.126637554585153	1.10093161376523	0.31899423635574	0.605488467736024
GO:0005337	nucleoside transmembrane transporter activity	2/2144	10/18639	0.2	1.73871268656716	0.322385755773791	0.605488467736024
GO:0005345	purine nucleobase transmembrane transporter activity	2/2144	10/18639	0.2	1.73871268656716	0.322385755773791	0.605488467736024
GO:0005522	profilin binding	2/2144	10/18639	0.2	1.73871268656716	0.322385755773791	0.605488467736024
GO:0015658	branched-chain amino acid transmembrane transporter activity	2/2144	10/18639	0.2	1.73871268656716	0.322385755773791	0.605488467736024
GO:0015924	mannosyl-oligosaccharide mannosidase activity	2/2144	10/18639	0.2	1.73871268656716	0.322385755773791	0.605488467736024
GO:0016303	1-phosphatidylinositol-3-kinase activity	2/2144	10/18639	0.2	1.73871268656716	0.322385755773791	0.605488467736024
GO:0016427	tRNA (cytidine) methyltransferase activity	2/2144	10/18639	0.2	1.73871268656716	0.322385755773791	0.605488467736024
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	2/2144	10/18639	0.2	1.73871268656716	0.322385755773791	0.605488467736024
GO:0031434	mitogen-activated protein kinase kinase binding	2/2144	10/18639	0.2	1.73871268656716	0.322385755773791	0.605488467736024
GO:0032356	oxidized DNA binding	2/2144	10/18639	0.2	1.73871268656716	0.322385755773791	0.605488467736024
GO:0042975	peroxisome proliferator activated receptor binding	2/2144	10/18639	0.2	1.73871268656716	0.322385755773791	0.605488467736024
GO:0043208	glycosphingolipid binding	2/2144	10/18639	0.2	1.73871268656716	0.322385755773791	0.605488467736024
GO:0050308	sugar-phosphatase activity	2/2144	10/18639	0.2	1.73871268656716	0.322385755773791	0.605488467736024
GO:0050815	phosphoserine residue binding	2/2144	10/18639	0.2	1.73871268656716	0.322385755773791	0.605488467736024
GO:0051880	G-quadruplex DNA binding	2/2144	10/18639	0.2	1.73871268656716	0.322385755773791	0.605488467736024
GO:0071723	lipopeptide binding	2/2144	10/18639	0.2	1.73871268656716	0.322385755773791	0.605488467736024
GO:0098505	G-rich strand telomeric DNA binding	2/2144	10/18639	0.2	1.73871268656716	0.322385755773791	0.605488467736024
GO:1990757	ubiquitin ligase activator activity	2/2144	10/18639	0.2	1.73871268656716	0.322385755773791	0.605488467736024
GO:0005537	D-mannose binding	4/2144	25/18639	0.16	1.39097014925373	0.322862545646271	0.605488467736024
GO:0015662	P-type ion transporter activity	4/2144	25/18639	0.16	1.39097014925373	0.322862545646271	0.605488467736024
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	4/2144	25/18639	0.16	1.39097014925373	0.322862545646271	0.605488467736024
GO:0017025	TBP-class protein binding	4/2144	25/18639	0.16	1.39097014925373	0.322862545646271	0.605488467736024
GO:0047617	fatty acyl-CoA hydrolase activity	4/2144	25/18639	0.16	1.39097014925373	0.322862545646271	0.605488467736024
GO:0140358	P-type transmembrane transporter activity	4/2144	25/18639	0.16	1.39097014925373	0.322862545646271	0.605488467736024
GO:0046943	carboxylic acid transmembrane transporter activity	24/2144	188/18639	0.127659574468085	1.10981660844713	0.324886582006877	0.608370825976896
GO:0030246	carbohydrate binding	35/2144	280/18639	0.125	1.08669542910448	0.325789587745625	0.609148495650128
GO:0019239	deaminase activity	5/2144	33/18639	0.151515151515152	1.3172065807327	0.328548896917058	0.613389495141115
GO:0160215	deacylase activity	9/2144	65/18639	0.138461538461538	1.20372416762342	0.329986251265202	0.615153474373488
GO:0001530	lipopolysaccharide binding	6/2144	41/18639	0.146341463414634	1.27222879504914	0.330943701852923	0.616018902554844
GO:0005342	organic acid transmembrane transporter activity	24/2144	189/18639	0.126984126984127	1.10394456289979	0.334621799088384	0.621938433127071
GO:0008170	N-methyltransferase activity	13/2144	98/18639	0.13265306122449	1.15322780231496	0.335953596576388	0.622560893358916
GO:0042626	ATPase-coupled transmembrane transporter activity	13/2144	98/18639	0.13265306122449	1.15322780231496	0.335953596576388	0.622560893358916
GO:0000400	four-way junction DNA binding	3/2144	18/18639	0.166666666666667	1.44892723880597	0.343267186316289	0.625898855049701
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	3/2144	18/18639	0.166666666666667	1.44892723880597	0.343267186316289	0.625898855049701
GO:0008525	phosphatidylcholine transporter activity	3/2144	18/18639	0.166666666666667	1.44892723880597	0.343267186316289	0.625898855049701
GO:0015373	monoatomic anion:sodium symporter activity	3/2144	18/18639	0.166666666666667	1.44892723880597	0.343267186316289	0.625898855049701
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	3/2144	18/18639	0.166666666666667	1.44892723880597	0.343267186316289	0.625898855049701
GO:0016854	racemase and epimerase activity	3/2144	18/18639	0.166666666666667	1.44892723880597	0.343267186316289	0.625898855049701
GO:0017075	syntaxin-1 binding	3/2144	18/18639	0.166666666666667	1.44892723880597	0.343267186316289	0.625898855049701
GO:0017128	phospholipid scramblase activity	3/2144	18/18639	0.166666666666667	1.44892723880597	0.343267186316289	0.625898855049701
GO:0032393	MHC class I receptor activity	3/2144	18/18639	0.166666666666667	1.44892723880597	0.343267186316289	0.625898855049701
GO:0070628	proteasome binding	3/2144	18/18639	0.166666666666667	1.44892723880597	0.343267186316289	0.625898855049701
GO:1990381	ubiquitin-specific protease binding	3/2144	18/18639	0.166666666666667	1.44892723880597	0.343267186316289	0.625898855049701
GO:0031491	nucleosome binding	10/2144	74/18639	0.135135135135135	1.17480586930214	0.34426033928256	0.626794699364311
GO:0004112	cyclic-nucleotide phosphodiesterase activity	4/2144	26/18639	0.153846153846154	1.33747129735936	0.350257185113861	0.633098732571942
GO:0016289	acyl-CoA hydrolase activity	4/2144	26/18639	0.153846153846154	1.33747129735936	0.350257185113861	0.633098732571942
GO:0030247	polysaccharide binding	4/2144	26/18639	0.153846153846154	1.33747129735936	0.350257185113861	0.633098732571942
GO:0043548	phosphatidylinositol 3-kinase binding	4/2144	26/18639	0.153846153846154	1.33747129735936	0.350257185113861	0.633098732571942
GO:0097602	cullin family protein binding	4/2144	26/18639	0.153846153846154	1.33747129735936	0.350257185113861	0.633098732571942
GO:0048020	CCR chemokine receptor binding	7/2144	50/18639	0.14	1.21709888059701	0.351039495700549	0.633281848061322
GO:0016831	carboxy-lyase activity	5/2144	34/18639	0.147058823529412	1.27846521071115	0.352386616815548	0.633281848061322
GO:0052866	phosphatidylinositol phosphate phosphatase activity	5/2144	34/18639	0.147058823529412	1.27846521071115	0.352386616815548	0.633281848061322
GO:0090482	vitamin transmembrane transporter activity	5/2144	34/18639	0.147058823529412	1.27846521071115	0.352386616815548	0.633281848061322
GO:0005496	steroid binding	14/2144	108/18639	0.12962962962963	1.1269434079602	0.359478345461719	0.639243226053898
GO:0044183	protein folding chaperone	10/2144	75/18639	0.133333333333333	1.15914179104478	0.360207760818376	0.639243226053898
GO:0016829	lyase activity	25/2144	200/18639	0.125	1.08669542910448	0.360276927451337	0.639243226053898
GO:0042054	histone methyltransferase activity	9/2144	67/18639	0.134328358208955	1.16779210291824	0.363755421899026	0.639243226053898
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	2/2144	11/18639	0.181818181818182	1.58064789687924	0.366451681228656	0.639243226053898
GO:0001851	complement component C3b binding	2/2144	11/18639	0.181818181818182	1.58064789687924	0.366451681228656	0.639243226053898
GO:0003953	NAD+ nucleosidase activity	2/2144	11/18639	0.181818181818182	1.58064789687924	0.366451681228656	0.639243226053898
GO:0008271	secondary active sulfate transmembrane transporter activity	2/2144	11/18639	0.181818181818182	1.58064789687924	0.366451681228656	0.639243226053898
GO:0015205	nucleobase transmembrane transporter activity	2/2144	11/18639	0.181818181818182	1.58064789687924	0.366451681228656	0.639243226053898
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	2/2144	11/18639	0.181818181818182	1.58064789687924	0.366451681228656	0.639243226053898
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	2/2144	11/18639	0.181818181818182	1.58064789687924	0.366451681228656	0.639243226053898
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/2144	11/18639	0.181818181818182	1.58064789687924	0.366451681228656	0.639243226053898
GO:0019203	carbohydrate phosphatase activity	2/2144	11/18639	0.181818181818182	1.58064789687924	0.366451681228656	0.639243226053898
GO:0019206	nucleoside kinase activity	2/2144	11/18639	0.181818181818182	1.58064789687924	0.366451681228656	0.639243226053898
GO:0019215	intermediate filament binding	2/2144	11/18639	0.181818181818182	1.58064789687924	0.366451681228656	0.639243226053898
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	2/2144	11/18639	0.181818181818182	1.58064789687924	0.366451681228656	0.639243226053898
GO:0045294	alpha-catenin binding	2/2144	11/18639	0.181818181818182	1.58064789687924	0.366451681228656	0.639243226053898
GO:0070697	activin receptor binding	2/2144	11/18639	0.181818181818182	1.58064789687924	0.366451681228656	0.639243226053898
GO:0097493	structural molecule activity conferring elasticity	2/2144	11/18639	0.181818181818182	1.58064789687924	0.366451681228656	0.639243226053898
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	2/2144	11/18639	0.181818181818182	1.58064789687924	0.366451681228656	0.639243226053898
GO:1990948	ubiquitin ligase inhibitor activity	2/2144	11/18639	0.181818181818182	1.58064789687924	0.366451681228656	0.639243226053898
GO:0016830	carbon-carbon lyase activity	7/2144	51/18639	0.137254901960784	1.19323419666374	0.370637559335388	0.645643391366666
GO:0004175	endopeptidase activity	49/2144	405/18639	0.120987654320988	1.05181384742952	0.374926858354388	0.647375426095077
GO:0008094	ATP-dependent activity, acting on DNA	26/2144	210/18639	0.123809523809524	1.07634594882729	0.375548659252389	0.647375426095077
GO:0008574	plus-end-directed microtubule motor activity	3/2144	19/18639	0.157894736842105	1.37266791044776	0.376242628524083	0.647375426095077
GO:0015245	fatty acid transmembrane transporter activity	3/2144	19/18639	0.157894736842105	1.37266791044776	0.376242628524083	0.647375426095077
GO:0034987	immunoglobulin receptor binding	3/2144	19/18639	0.157894736842105	1.37266791044776	0.376242628524083	0.647375426095077
GO:0046624	sphingolipid transporter activity	3/2144	19/18639	0.157894736842105	1.37266791044776	0.376242628524083	0.647375426095077
GO:0050145	nucleoside monophosphate kinase activity	3/2144	19/18639	0.157894736842105	1.37266791044776	0.376242628524083	0.647375426095077
GO:0120227	acyl-CoA binding	3/2144	19/18639	0.157894736842105	1.37266791044776	0.376242628524083	0.647375426095077
GO:0005343	organic acid:sodium symporter activity	5/2144	35/18639	0.142857142857143	1.24193763326226	0.37629668482388	0.647375426095077
GO:0008320	protein transmembrane transporter activity	4/2144	27/18639	0.148148148148148	1.28793532338308	0.377664558863133	0.647943728049523
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	4/2144	27/18639	0.148148148148148	1.28793532338308	0.377664558863133	0.647943728049523
GO:0140223	general transcription initiation factor activity	9/2144	68/18639	0.132352941176471	1.15061868964003	0.380785465674675	0.652401984400094
GO:0004222	metalloendopeptidase activity	14/2144	110/18639	0.127272727272727	1.10645352781547	0.386178999283477	0.660736397404195
GO:0005178	integrin binding	20/2144	161/18639	0.124223602484472	1.07994576805414	0.392586486962754	0.670090025855736
GO:0016790	thiolester hydrolase activity	6/2144	44/18639	0.136363636363636	1.18548592265943	0.395228326910212	0.670090025855736
GO:0044325	transmembrane transporter binding	17/2144	136/18639	0.125	1.08669542910448	0.396213817573296	0.670090025855736
GO:0003774	cytoskeletal motor activity	19/2144	153/18639	0.124183006535948	1.07959284460053	0.397617826263562	0.670090025855736
GO:0004190	aspartic-type endopeptidase activity	5/2144	36/18639	0.138888888888889	1.20743936567164	0.400188137999924	0.670090025855736
GO:0050660	flavin adenine dinucleotide binding	11/2144	86/18639	0.127906976744186	1.11196741582784	0.402424060813506	0.670090025855736
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	8/2144	61/18639	0.131147540983607	1.14013946660142	0.403718302111011	0.670090025855736
GO:0033218	amide binding	30/2144	247/18639	0.121457489878543	1.05589839265212	0.404286988518687	0.670090025855736
GO:0019789	SUMO transferase activity	4/2144	28/18639	0.142857142857143	1.24193763326226	0.404952654873652	0.670090025855736
GO:0045499	chemorepellent activity	4/2144	28/18639	0.142857142857143	1.24193763326226	0.404952654873652	0.670090025855736
GO:0051393	alpha-actinin binding	4/2144	28/18639	0.142857142857143	1.24193763326226	0.404952654873652	0.670090025855736
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	4/2144	28/18639	0.142857142857143	1.24193763326226	0.404952654873652	0.670090025855736
GO:0000339	RNA cap binding	3/2144	20/18639	0.15	1.30403451492537	0.408859814126859	0.670090025855736
GO:0001972	retinoic acid binding	3/2144	20/18639	0.15	1.30403451492537	0.408859814126859	0.670090025855736
GO:0000995	RNA polymerase III general transcription initiation factor activity	2/2144	12/18639	0.166666666666667	1.44892723880597	0.409350432128044	0.670090025855736
GO:0004859	phospholipase inhibitor activity	2/2144	12/18639	0.166666666666667	1.44892723880597	0.409350432128044	0.670090025855736
GO:0005165	neurotrophin receptor binding	2/2144	12/18639	0.166666666666667	1.44892723880597	0.409350432128044	0.670090025855736
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	2/2144	12/18639	0.166666666666667	1.44892723880597	0.409350432128044	0.670090025855736
GO:0010853	cyclase activator activity	2/2144	12/18639	0.166666666666667	1.44892723880597	0.409350432128044	0.670090025855736
GO:0015166	polyol transmembrane transporter activity	2/2144	12/18639	0.166666666666667	1.44892723880597	0.409350432128044	0.670090025855736
GO:0016208	AMP binding	2/2144	12/18639	0.166666666666667	1.44892723880597	0.409350432128044	0.670090025855736
GO:0016273	arginine N-methyltransferase activity	2/2144	12/18639	0.166666666666667	1.44892723880597	0.409350432128044	0.670090025855736
GO:0016274	protein-arginine N-methyltransferase activity	2/2144	12/18639	0.166666666666667	1.44892723880597	0.409350432128044	0.670090025855736
GO:0034452	dynactin binding	2/2144	12/18639	0.166666666666667	1.44892723880597	0.409350432128044	0.670090025855736
GO:0035197	siRNA binding	2/2144	12/18639	0.166666666666667	1.44892723880597	0.409350432128044	0.670090025855736
GO:0043047	single-stranded telomeric DNA binding	2/2144	12/18639	0.166666666666667	1.44892723880597	0.409350432128044	0.670090025855736
GO:0045295	gamma-catenin binding	2/2144	12/18639	0.166666666666667	1.44892723880597	0.409350432128044	0.670090025855736
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	2/2144	12/18639	0.166666666666667	1.44892723880597	0.409350432128044	0.670090025855736
GO:0070008	serine-type exopeptidase activity	2/2144	12/18639	0.166666666666667	1.44892723880597	0.409350432128044	0.670090025855736
GO:0070679	inositol 1,4,5 trisphosphate binding	2/2144	12/18639	0.166666666666667	1.44892723880597	0.409350432128044	0.670090025855736
GO:0140829	bicarbonate:monoatomic anion antiporter activity	2/2144	12/18639	0.166666666666667	1.44892723880597	0.409350432128044	0.670090025855736
GO:0140900	chloride:bicarbonate antiporter activity	2/2144	12/18639	0.166666666666667	1.44892723880597	0.409350432128044	0.670090025855736
GO:0141221	histone deacetylase activity, hydrolytic mechanism	2/2144	12/18639	0.166666666666667	1.44892723880597	0.409350432128044	0.670090025855736
GO:0016251	RNA polymerase II general transcription initiation factor activity	7/2144	53/18639	0.132075471698113	1.14820649112926	0.409961907218695	0.670212594392866
GO:0008276	protein methyltransferase activity	12/2144	95/18639	0.126315789473684	1.09813432835821	0.411339055696467	0.671584941914885
GO:0051539	4 iron, 4 sulfur cluster binding	6/2144	45/18639	0.133333333333333	1.15914179104478	0.416678192554391	0.67941391971336
GO:0019213	deacetylase activity	5/2144	37/18639	0.135135135135135	1.17480586930214	0.423975564529338	0.690411316945429
GO:0016798	hydrolase activity, acting on glycosyl bonds	16/2144	130/18639	0.123076923076923	1.06997703788749	0.426667321508568	0.693889953859637
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	4/2144	29/18639	0.137931034482759	1.19911219763253	0.432001050817768	0.699830496071845
GO:0097472	cyclin-dependent protein kinase activity	4/2144	29/18639	0.137931034482759	1.19911219763253	0.432001050817768	0.699830496071845
GO:0099604	ligand-gated calcium channel activity	4/2144	29/18639	0.137931034482759	1.19911219763253	0.432001050817768	0.699830496071845
GO:0004180	carboxypeptidase activity	6/2144	46/18639	0.130434782608696	1.13394305645685	0.438034617351136	0.707874346199245
GO:0048306	calcium-dependent protein binding	10/2144	80/18639	0.125	1.08669542910448	0.440754694182737	0.707874346199245
GO:0001846	opsonin binding	3/2144	21/18639	0.142857142857143	1.24193763326226	0.440933740066463	0.707874346199245
GO:0008373	sialyltransferase activity	3/2144	21/18639	0.142857142857143	1.24193763326226	0.440933740066463	0.707874346199245
GO:0009975	cyclase activity	3/2144	21/18639	0.142857142857143	1.24193763326226	0.440933740066463	0.707874346199245
GO:0010314	phosphatidylinositol-5-phosphate binding	3/2144	21/18639	0.142857142857143	1.24193763326226	0.440933740066463	0.707874346199245
GO:0070182	DNA polymerase binding	3/2144	21/18639	0.142857142857143	1.24193763326226	0.440933740066463	0.707874346199245
GO:0005501	retinoid binding	5/2144	38/18639	0.131578947368421	1.14388992537313	0.44757950889063	0.713572363734334
GO:0019840	isoprenoid binding	5/2144	38/18639	0.131578947368421	1.14388992537313	0.44757950889063	0.713572363734334
GO:0008035	high-density lipoprotein particle binding	2/2144	13/18639	0.153846153846154	1.33747129735936	0.450767489981096	0.713572363734334
GO:0019855	calcium channel inhibitor activity	2/2144	13/18639	0.153846153846154	1.33747129735936	0.450767489981096	0.713572363734334
GO:0030955	potassium ion binding	2/2144	13/18639	0.153846153846154	1.33747129735936	0.450767489981096	0.713572363734334
GO:0032396	inhibitory MHC class I receptor activity	2/2144	13/18639	0.153846153846154	1.33747129735936	0.450767489981096	0.713572363734334
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	2/2144	13/18639	0.153846153846154	1.33747129735936	0.450767489981096	0.713572363734334
GO:0051011	microtubule minus-end binding	2/2144	13/18639	0.153846153846154	1.33747129735936	0.450767489981096	0.713572363734334
GO:0061459	L-arginine transmembrane transporter activity	2/2144	13/18639	0.153846153846154	1.33747129735936	0.450767489981096	0.713572363734334
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	2/2144	13/18639	0.153846153846154	1.33747129735936	0.450767489981096	0.713572363734334
GO:0140410	monoatomic cation:bicarbonate symporter activity	2/2144	13/18639	0.153846153846154	1.33747129735936	0.450767489981096	0.713572363734334
GO:0008237	metallopeptidase activity	22/2144	184/18639	0.119565217391304	1.03944780175211	0.457442245036714	0.72322197981121
GO:0015215	nucleotide transmembrane transporter activity	4/2144	30/18639	0.133333333333333	1.15914179104478	0.458701181753966	0.723381030316544
GO:0031210	phosphatidylcholine binding	4/2144	30/18639	0.133333333333333	1.15914179104478	0.458701181753966	0.723381030316544
GO:0170055	lipid transmembrane transporter activity	7/2144	56/18639	0.125	1.08669542910448	0.468543782342021	0.737971228430245
GO:0050321	tau-protein kinase activity	3/2144	22/18639	0.136363636363636	1.18548592265943	0.472307237224968	0.742961888279579
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	11/2144	91/18639	0.120879120879121	1.05087030506807	0.478852516122193	0.752310430989459
GO:0003684	damaged DNA binding	9/2144	74/18639	0.121621621621622	1.05732528237192	0.482931946220465	0.756301989587127
GO:0005310	dicarboxylic acid transmembrane transporter activity	4/2144	31/18639	0.129032258064516	1.12175012036591	0.48495636630554	0.756301989587127
GO:0047499	calcium-independent phospholipase A2 activity	4/2144	31/18639	0.129032258064516	1.12175012036591	0.48495636630554	0.756301989587127
GO:0031406	carboxylic acid binding	22/2144	187/18639	0.117647058823529	1.02277216856892	0.489307721149064	0.756301989587127
GO:0004065	arylsulfatase activity	2/2144	14/18639	0.142857142857143	1.24193763326226	0.490476070108545	0.756301989587127
GO:0005347	ATP transmembrane transporter activity	2/2144	14/18639	0.142857142857143	1.24193763326226	0.490476070108545	0.756301989587127
GO:0016530	metallochaperone activity	2/2144	14/18639	0.142857142857143	1.24193763326226	0.490476070108545	0.756301989587127
GO:0019992	diacylglycerol binding	2/2144	14/18639	0.142857142857143	1.24193763326226	0.490476070108545	0.756301989587127
GO:0030983	mismatched DNA binding	2/2144	14/18639	0.142857142857143	1.24193763326226	0.490476070108545	0.756301989587127
GO:0031404	chloride ion binding	2/2144	14/18639	0.142857142857143	1.24193763326226	0.490476070108545	0.756301989587127
GO:0042043	neurexin family protein binding	2/2144	14/18639	0.142857142857143	1.24193763326226	0.490476070108545	0.756301989587127
GO:0043176	amine binding	2/2144	14/18639	0.142857142857143	1.24193763326226	0.490476070108545	0.756301989587127
GO:0061665	SUMO ligase activity	2/2144	14/18639	0.142857142857143	1.24193763326226	0.490476070108545	0.756301989587127
GO:0098847	sequence-specific single stranded DNA binding	2/2144	14/18639	0.142857142857143	1.24193763326226	0.490476070108545	0.756301989587127
GO:1990825	sequence-specific mRNA binding	2/2144	14/18639	0.142857142857143	1.24193763326226	0.490476070108545	0.756301989587127
GO:0004602	glutathione peroxidase activity	3/2144	23/18639	0.130434782608696	1.13394305645685	0.502849253291031	0.772519947552888
GO:0031681	G-protein beta-subunit binding	3/2144	23/18639	0.130434782608696	1.13394305645685	0.502849253291031	0.772519947552888
GO:0140103	catalytic activity, acting on a glycoprotein	3/2144	23/18639	0.130434782608696	1.13394305645685	0.502849253291031	0.772519947552888
GO:0017116	single-stranded DNA helicase activity	7/2144	58/18639	0.120689655172414	1.04922317292846	0.50681773817546	0.777660141254484
GO:0043177	organic acid binding	22/2144	189/18639	0.116402116402116	1.01194918265814	0.51040233327899	0.782199404006697
GO:0017022	myosin binding	9/2144	76/18639	0.118421052631579	1.02950093283582	0.516245926167286	0.790185247283016
GO:0015605	organophosphate ester transmembrane transporter activity	6/2144	50/18639	0.12	1.0432276119403	0.521436317453597	0.795027797566277
GO:0001786	phosphatidylserine binding	7/2144	59/18639	0.11864406779661	1.0314397293195	0.525604543565919	0.795027797566277
GO:0015459	potassium channel regulator activity	7/2144	59/18639	0.11864406779661	1.0314397293195	0.525604543565919	0.795027797566277
GO:0004089	carbonate dehydratase activity	2/2144	15/18639	0.133333333333333	1.15914179104478	0.528321114475588	0.795027797566277
GO:0004559	alpha-mannosidase activity	2/2144	15/18639	0.133333333333333	1.15914179104478	0.528321114475588	0.795027797566277
GO:0010181	FMN binding	2/2144	15/18639	0.133333333333333	1.15914179104478	0.528321114475588	0.795027797566277
GO:0015116	sulfate transmembrane transporter activity	2/2144	15/18639	0.133333333333333	1.15914179104478	0.528321114475588	0.795027797566277
GO:0015929	hexosaminidase activity	2/2144	15/18639	0.133333333333333	1.15914179104478	0.528321114475588	0.795027797566277
GO:0016846	carbon-sulfur lyase activity	2/2144	15/18639	0.133333333333333	1.15914179104478	0.528321114475588	0.795027797566277
GO:0031005	filamin binding	2/2144	15/18639	0.133333333333333	1.15914179104478	0.528321114475588	0.795027797566277
GO:0031386	protein tag activity	2/2144	15/18639	0.133333333333333	1.15914179104478	0.528321114475588	0.795027797566277
GO:0045504	dynein heavy chain binding	2/2144	15/18639	0.133333333333333	1.15914179104478	0.528321114475588	0.795027797566277
GO:0048531	beta-1,3-galactosyltransferase activity	2/2144	15/18639	0.133333333333333	1.15914179104478	0.528321114475588	0.795027797566277
GO:0141047	molecular tag activity	2/2144	15/18639	0.133333333333333	1.15914179104478	0.528321114475588	0.795027797566277
GO:0003777	microtubule motor activity	8/2144	68/18639	0.117647058823529	1.02277216856892	0.529299778765862	0.795542026087319
GO:0035035	histone acetyltransferase binding	3/2144	24/18639	0.125	1.08669542910448	0.532452905648022	0.798359758888811
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	3/2144	24/18639	0.125	1.08669542910448	0.532452905648022	0.798359758888811
GO:0004867	serine-type endopeptidase inhibitor activity	11/2144	95/18639	0.115789473684211	1.00662313432836	0.538570574278028	0.805930056516133
GO:0042056	chemoattractant activity	5/2144	42/18639	0.119047619047619	1.03494802771855	0.538792311602059	0.805930056516133
GO:0003730	mRNA 3'-UTR binding	30/2144	262/18639	0.114503816793893	0.995446194599522	0.539867777796959	0.806572792426318
GO:0008509	monoatomic anion transmembrane transporter activity	17/2144	149/18639	0.114093959731544	0.99188307622959	0.552735347286325	0.824810571995961
GO:0008175	tRNA methyltransferase activity	4/2144	34/18639	0.117647058823529	1.02277216856892	0.560258960411344	0.829050645611523
GO:0015035	protein-disulfide reductase activity	4/2144	34/18639	0.117647058823529	1.02277216856892	0.560258960411344	0.829050645611523
GO:0003707	nuclear steroid receptor activity	3/2144	25/18639	0.12	1.0432276119403	0.561033409284625	0.829050645611523
GO:0015645	fatty acid ligase activity	3/2144	25/18639	0.12	1.0432276119403	0.561033409284625	0.829050645611523
GO:0017056	structural constituent of nuclear pore	3/2144	25/18639	0.12	1.0432276119403	0.561033409284625	0.829050645611523
GO:0120515	fatty acid-CoA ligase activity	3/2144	25/18639	0.12	1.0432276119403	0.561033409284625	0.829050645611523
GO:0016836	hydro-lyase activity	7/2144	61/18639	0.114754098360656	0.997622033276242	0.562312034660734	0.829050645611523
GO:0016782	transferase activity, transferring sulphur-containing groups	8/2144	70/18639	0.114285714285714	0.993550106609808	0.563513463335867	0.829050645611523
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	2/2144	16/18639	0.125	1.08669542910448	0.564205803658763	0.829050645611523
GO:0005324	long-chain fatty acid transmembrane transporter activity	2/2144	16/18639	0.125	1.08669542910448	0.564205803658763	0.829050645611523
GO:0005521	lamin binding	2/2144	16/18639	0.125	1.08669542910448	0.564205803658763	0.829050645611523
GO:0017070	U6 snRNA binding	2/2144	16/18639	0.125	1.08669542910448	0.564205803658763	0.829050645611523
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	2/2144	16/18639	0.125	1.08669542910448	0.564205803658763	0.829050645611523
GO:0005246	calcium channel regulator activity	6/2144	53/18639	0.113207547169811	0.984176992396508	0.580586799836087	0.851748825885894
GO:0030547	signaling receptor inhibitor activity	5/2144	44/18639	0.113636363636364	0.987904935549525	0.581698757790766	0.851748825885894
GO:0043014	alpha-tubulin binding	5/2144	44/18639	0.113636363636364	0.987904935549525	0.581698757790766	0.851748825885894
GO:0004623	phospholipase A2 activity	4/2144	35/18639	0.114285714285714	0.993550106609808	0.583996028229081	0.854111287187497
GO:0008198	ferrous iron binding	3/2144	26/18639	0.115384615384615	1.00310347301952	0.58852596026342	0.858725378935761
GO:0050750	low-density lipoprotein particle receptor binding	3/2144	26/18639	0.115384615384615	1.00310347301952	0.58852596026342	0.858725378935761
GO:0008569	minus-end-directed microtubule motor activity	2/2144	17/18639	0.117647058823529	1.02277216856892	0.598080220594259	0.866591874155719
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	2/2144	17/18639	0.117647058823529	1.02277216856892	0.598080220594259	0.866591874155719
GO:0009881	photoreceptor activity	2/2144	17/18639	0.117647058823529	1.02277216856892	0.598080220594259	0.866591874155719
GO:0016018	cyclosporin A binding	2/2144	17/18639	0.117647058823529	1.02277216856892	0.598080220594259	0.866591874155719
GO:0031489	myosin V binding	2/2144	17/18639	0.117647058823529	1.02277216856892	0.598080220594259	0.866591874155719
GO:0070492	oligosaccharide binding	2/2144	17/18639	0.117647058823529	1.02277216856892	0.598080220594259	0.866591874155719
GO:0141110	transporter inhibitor activity	5/2144	45/18639	0.111111111111111	0.965951492537313	0.602326328445313	0.871733006058165
GO:0005125	cytokine activity	26/2144	234/18639	0.111111111111111	0.965951492537313	0.605678937679286	0.875570593936839
GO:0045505	dynein intermediate chain binding	4/2144	36/18639	0.111111111111111	0.965951492537313	0.606972014507726	0.876425486844104
GO:0004519	endonuclease activity	14/2144	127/18639	0.110236220472441	0.95834557527324	0.608942826660136	0.878255878173799
GO:0004521	RNA endonuclease activity	8/2144	73/18639	0.10958904109589	0.952719280310775	0.612660224119974	0.879713242454331
GO:0004536	DNA nuclease activity	7/2144	64/18639	0.109375	0.950858500466418	0.614795238767756	0.879713242454331
GO:0004364	glutathione transferase activity	3/2144	27/18639	0.111111111111111	0.965951492537313	0.614883635438456	0.879713242454331
GO:0005385	zinc ion transmembrane transporter activity	3/2144	27/18639	0.111111111111111	0.965951492537313	0.614883635438456	0.879713242454331
GO:0016405	CoA-ligase activity	3/2144	27/18639	0.111111111111111	0.965951492537313	0.614883635438456	0.879713242454331
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	3/2144	27/18639	0.111111111111111	0.965951492537313	0.614883635438456	0.879713242454331
GO:0035255	ionotropic glutamate receptor binding	3/2144	27/18639	0.111111111111111	0.965951492537313	0.614883635438456	0.879713242454331
GO:0008374	O-acyltransferase activity	6/2144	55/18639	0.109090909090909	0.948388738127544	0.617869256894398	0.882973343090506
GO:0046873	metal ion transmembrane transporter activity	50/2144	450/18639	0.111111111111111	0.965951492537313	0.62627985406794	0.893969757406693
GO:0003678	DNA helicase activity	8/2144	74/18639	0.108108108108108	0.93984469544171	0.628384863865369	0.895090876563001
GO:0030551	cyclic nucleotide binding	4/2144	37/18639	0.108108108108108	0.93984469544171	0.629153402383894	0.895090876563001
GO:0008409	5'-3' exonuclease activity	2/2144	18/18639	0.111111111111111	0.965951492537313	0.629931849879006	0.895090876563001
GO:0035615	clathrin adaptor activity	2/2144	18/18639	0.111111111111111	0.965951492537313	0.629931849879006	0.895090876563001
GO:0030170	pyridoxal phosphate binding	6/2144	56/18639	0.107142857142857	0.931453224946695	0.635788313840682	0.902385913621605
GO:0016866	intramolecular transferase activity	3/2144	28/18639	0.107142857142857	0.931453224946695	0.640075353106232	0.907439405255033
GO:0000146	microfilament motor activity	4/2144	38/18639	0.105263157894737	0.915111940298508	0.650515036912513	0.915624747936309
GO:0042887	amide transmembrane transporter activity	4/2144	38/18639	0.105263157894737	0.915111940298508	0.650515036912513	0.915624747936309
GO:0015078	proton transmembrane transporter activity	20/2144	185/18639	0.108108108108108	0.93984469544171	0.650806715228502	0.915624747936309
GO:0042562	hormone binding	10/2144	94/18639	0.106382978723404	0.924847173705938	0.651863924871734	0.915624747936309
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	18/2144	167/18639	0.107784431137725	0.937030789167933	0.651911559839337	0.915624747936309
GO:0004601	peroxidase activity	6/2144	57/18639	0.105263157894737	0.915111940298508	0.653200409782233	0.915624747936309
GO:0015932	nucleobase-containing compound transmembrane transporter activity	6/2144	57/18639	0.105263157894737	0.915111940298508	0.653200409782233	0.915624747936309
GO:0070279	vitamin B6 binding	6/2144	57/18639	0.105263157894737	0.915111940298508	0.653200409782233	0.915624747936309
GO:0051536	iron-sulfur cluster binding	8/2144	76/18639	0.105263157894737	0.915111940298508	0.658755121523408	0.915624747936309
GO:0008168	methyltransferase activity	22/2144	204/18639	0.107843137254902	0.93754115452151	0.659363829508122	0.915624747936309
GO:0003756	protein disulfide isomerase activity	2/2144	19/18639	0.105263157894737	0.915111940298508	0.659777640626644	0.915624747936309
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	2/2144	19/18639	0.105263157894737	0.915111940298508	0.659777640626644	0.915624747936309
GO:0005346	purine ribonucleotide transmembrane transporter activity	2/2144	19/18639	0.105263157894737	0.915111940298508	0.659777640626644	0.915624747936309
GO:0005520	insulin-like growth factor binding	2/2144	19/18639	0.105263157894737	0.915111940298508	0.659777640626644	0.915624747936309
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	2/2144	19/18639	0.105263157894737	0.915111940298508	0.659777640626644	0.915624747936309
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	2/2144	19/18639	0.105263157894737	0.915111940298508	0.659777640626644	0.915624747936309
GO:0016918	retinal binding	2/2144	19/18639	0.105263157894737	0.915111940298508	0.659777640626644	0.915624747936309
GO:0042800	histone H3K4 methyltransferase activity	2/2144	19/18639	0.105263157894737	0.915111940298508	0.659777640626644	0.915624747936309
GO:0043395	heparan sulfate proteoglycan binding	2/2144	19/18639	0.105263157894737	0.915111940298508	0.659777640626644	0.915624747936309
GO:0004181	metallocarboxypeptidase activity	3/2144	29/18639	0.103448275862069	0.899334148224395	0.664083926447209	0.919557454692421
GO:0035250	UDP-galactosyltransferase activity	3/2144	29/18639	0.103448275862069	0.899334148224395	0.664083926447209	0.919557454692421
GO:0051540	metal cluster binding	8/2144	77/18639	0.103896103896104	0.90322736964528	0.673376687110024	0.926504273126785
GO:0016741	transferase activity, transferring one-carbon groups	23/2144	215/18639	0.106976744186047	0.930009111419646	0.676677202974527	0.926504273126785
GO:0035254	glutamate receptor binding	5/2144	49/18639	0.102040816326531	0.887098309473043	0.678698483773899	0.926504273126785
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	6/2144	59/18639	0.101694915254237	0.884091196559575	0.686447643457228	0.926504273126785
GO:0070888	E-box binding	6/2144	59/18639	0.101694915254237	0.884091196559575	0.686447643457228	0.926504273126785
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	3/2144	30/18639	0.1	0.869356343283582	0.686904231413125	0.926504273126785
GO:0033612	receptor serine/threonine kinase binding	3/2144	30/18639	0.1	0.869356343283582	0.686904231413125	0.926504273126785
GO:0048019	receptor antagonist activity	3/2144	30/18639	0.1	0.869356343283582	0.686904231413125	0.926504273126785
GO:0016505	peptidase activator activity involved in apoptotic process	2/2144	20/18639	0.1	0.869356343283582	0.68765739912662	0.926504273126785
GO:0004177	aminopeptidase activity	4/2144	40/18639	0.1	0.869356343283582	0.690715962318181	0.926504273126785
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	4/2144	40/18639	0.1	0.869356343283582	0.690715962318181	0.926504273126785
GO:0050997	quaternary ammonium group binding	4/2144	40/18639	0.1	0.869356343283582	0.690715962318181	0.926504273126785
GO:0016835	carbon-oxygen lyase activity	8/2144	79/18639	0.10126582278481	0.880360853958058	0.701446337087279	0.926504273126785
GO:0000182	rDNA binding	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0001094	TFIID-class transcription factor complex binding	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0003796	lysozyme activity	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0004935	adrenergic receptor activity	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0005131	growth hormone receptor binding	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0005528	FK506 binding	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0008190	eukaryotic initiation factor 4E binding	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0008519	ammonium channel activity	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0015187	glycine transmembrane transporter activity	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0015203	polyamine transmembrane transporter activity	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0016868	intramolecular phosphotransferase activity	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0032052	bile acid binding	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0035256	G protein-coupled glutamate receptor binding	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0035374	chondroitin sulfate binding	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0043121	neurotrophin binding	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0045322	unmethylated CpG binding	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0047429	nucleoside triphosphate diphosphatase activity	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0070097	delta-catenin binding	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0140135	mechanosensitive monoatomic cation channel activity	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0140940	histone H2A methyltransferase activity	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0140999	histone H3K4 trimethyltransferase activity	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:1990259	histone H2AQ104 methyltransferase activity	1/2144	10/18639	0.1	0.869356343283582	0.705448810042892	0.926504273126785
GO:0008327	methyl-CpG binding	3/2144	31/18639	0.0967741935483871	0.841312590274434	0.708541502674652	0.927639766080335
GO:0016878	acid-thiol ligase activity	3/2144	31/18639	0.0967741935483871	0.841312590274434	0.708541502674652	0.927639766080335
GO:0070325	lipoprotein particle receptor binding	3/2144	31/18639	0.0967741935483871	0.841312590274434	0.708541502674652	0.927639766080335
GO:0017080	sodium channel regulator activity	4/2144	41/18639	0.0975609756097561	0.848152530032763	0.709540358996441	0.927974773179638
GO:0019838	growth factor binding	14/2144	136/18639	0.102941176470588	0.894925647497805	0.710505175375219	0.928264606740219
GO:0015174	basic amino acid transmembrane transporter activity	2/2144	21/18639	0.0952380952380952	0.82795842217484	0.713628310606636	0.929428321113336
GO:0019200	carbohydrate kinase activity	2/2144	21/18639	0.0952380952380952	0.82795842217484	0.713628310606636	0.929428321113336
GO:0140312	cargo adaptor activity	2/2144	21/18639	0.0952380952380952	0.82795842217484	0.713628310606636	0.929428321113336
GO:0008378	galactosyltransferase activity	3/2144	32/18639	0.09375	0.815021571828358	0.729009764975202	0.934662252158371
GO:0015106	bicarbonate transmembrane transporter activity	3/2144	32/18639	0.09375	0.815021571828358	0.729009764975202	0.934662252158371
GO:0031369	translation initiation factor binding	3/2144	32/18639	0.09375	0.815021571828358	0.729009764975202	0.934662252158371
GO:0047498	calcium-dependent phospholipase A2 activity	3/2144	32/18639	0.09375	0.815021571828358	0.729009764975202	0.934662252158371
GO:0005518	collagen binding	7/2144	72/18639	0.0972222222222222	0.845207555970149	0.736174058389358	0.934662252158371
GO:0008093	cytoskeletal anchor activity	2/2144	22/18639	0.0909090909090909	0.79032394843962	0.737760417944803	0.934662252158371
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	2/2144	22/18639	0.0909090909090909	0.79032394843962	0.737760417944803	0.934662252158371
GO:0016881	acid-amino acid ligase activity	2/2144	22/18639	0.0909090909090909	0.79032394843962	0.737760417944803	0.934662252158371
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	1/2144	11/18639	0.0909090909090909	0.79032394843962	0.739348522924316	0.934662252158371
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	1/2144	11/18639	0.0909090909090909	0.79032394843962	0.739348522924316	0.934662252158371
GO:0002162	dystroglycan binding	1/2144	11/18639	0.0909090909090909	0.79032394843962	0.739348522924316	0.934662252158371
GO:0005114	type II transforming growth factor beta receptor binding	1/2144	11/18639	0.0909090909090909	0.79032394843962	0.739348522924316	0.934662252158371
GO:0005536	D-glucose binding	1/2144	11/18639	0.0909090909090909	0.79032394843962	0.739348522924316	0.934662252158371
GO:0008199	ferric iron binding	1/2144	11/18639	0.0909090909090909	0.79032394843962	0.739348522924316	0.934662252158371
GO:0008526	phosphatidylinositol transfer activity	1/2144	11/18639	0.0909090909090909	0.79032394843962	0.739348522924316	0.934662252158371
GO:0015217	ADP transmembrane transporter activity	1/2144	11/18639	0.0909090909090909	0.79032394843962	0.739348522924316	0.934662252158371
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/2144	11/18639	0.0909090909090909	0.79032394843962	0.739348522924316	0.934662252158371
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/2144	11/18639	0.0909090909090909	0.79032394843962	0.739348522924316	0.934662252158371
GO:0031731	CCR6 chemokine receptor binding	1/2144	11/18639	0.0909090909090909	0.79032394843962	0.739348522924316	0.934662252158371
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	1/2144	11/18639	0.0909090909090909	0.79032394843962	0.739348522924316	0.934662252158371
GO:0032404	mismatch repair complex binding	1/2144	11/18639	0.0909090909090909	0.79032394843962	0.739348522924316	0.934662252158371
GO:0032794	GTPase activating protein binding	1/2144	11/18639	0.0909090909090909	0.79032394843962	0.739348522924316	0.934662252158371
GO:0034511	U3 snoRNA binding	1/2144	11/18639	0.0909090909090909	0.79032394843962	0.739348522924316	0.934662252158371
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/2144	11/18639	0.0909090909090909	0.79032394843962	0.739348522924316	0.934662252158371
GO:0035252	UDP-xylosyltransferase activity	1/2144	11/18639	0.0909090909090909	0.79032394843962	0.739348522924316	0.934662252158371
GO:0042285	xylosyltransferase activity	1/2144	11/18639	0.0909090909090909	0.79032394843962	0.739348522924316	0.934662252158371
GO:0048185	activin binding	1/2144	11/18639	0.0909090909090909	0.79032394843962	0.739348522924316	0.934662252158371
GO:0050998	nitric-oxide synthase binding	1/2144	11/18639	0.0909090909090909	0.79032394843962	0.739348522924316	0.934662252158371
GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/2144	11/18639	0.0909090909090909	0.79032394843962	0.739348522924316	0.934662252158371
GO:0052689	carboxylic ester hydrolase activity	9/2144	92/18639	0.0978260869565217	0.850457292342635	0.745104667546147	0.940986582168997
GO:0005507	copper ion binding	6/2144	63/18639	0.0952380952380952	0.82795842217484	0.746411848111522	0.941685250799284
GO:0015108	chloride transmembrane transporter activity	12/2144	121/18639	0.0991735537190083	0.862171580115949	0.749184571928446	0.944026402341836
GO:0008238	exopeptidase activity	10/2144	102/18639	0.0980392156862745	0.8523101404741	0.749779176239472	0.944026402341836
GO:0005200	structural constituent of cytoskeleton	11/2144	112/18639	0.0982142857142857	0.853832122867804	0.754478490807188	0.945783551526638
GO:0000295	adenine nucleotide transmembrane transporter activity	2/2144	23/18639	0.0869565217391304	0.755962037637897	0.760132909816591	0.945783551526638
GO:0017134	fibroblast growth factor binding	2/2144	23/18639	0.0869565217391304	0.755962037637897	0.760132909816591	0.945783551526638
GO:0016248	channel inhibitor activity	4/2144	44/18639	0.0909090909090909	0.79032394843962	0.760936924296048	0.945783551526638
GO:0048029	monosaccharide binding	7/2144	74/18639	0.0945945945945946	0.822364108511497	0.761904219859649	0.945783551526638
GO:0008376	acetylgalactosaminyltransferase activity	3/2144	34/18639	0.0882352941176471	0.76707912642669	0.76653086454446	0.945783551526638
GO:0003720	telomerase activity	1/2144	12/18639	0.0833333333333333	0.724463619402985	0.76934834936034	0.945783551526638
GO:0004126	cytidine deaminase activity	1/2144	12/18639	0.0833333333333333	0.724463619402985	0.76934834936034	0.945783551526638
GO:0005025	transforming growth factor beta receptor activity, type I	1/2144	12/18639	0.0833333333333333	0.724463619402985	0.76934834936034	0.945783551526638
GO:0005026	transforming growth factor beta receptor activity, type II	1/2144	12/18639	0.0833333333333333	0.724463619402985	0.76934834936034	0.945783551526638
GO:0005247	voltage-gated chloride channel activity	1/2144	12/18639	0.0833333333333333	0.724463619402985	0.76934834936034	0.945783551526638
GO:0005527	macrolide binding	1/2144	12/18639	0.0833333333333333	0.724463619402985	0.76934834936034	0.945783551526638
GO:0008179	adenylate cyclase binding	1/2144	12/18639	0.0833333333333333	0.724463619402985	0.76934834936034	0.945783551526638
GO:0008504	monoamine transmembrane transporter activity	1/2144	12/18639	0.0833333333333333	0.724463619402985	0.76934834936034	0.945783551526638
GO:0008603	cAMP-dependent protein kinase regulator activity	1/2144	12/18639	0.0833333333333333	0.724463619402985	0.76934834936034	0.945783551526638
GO:0016361	activin receptor activity, type I	1/2144	12/18639	0.0833333333333333	0.724463619402985	0.76934834936034	0.945783551526638
GO:0016362	activin receptor activity, type II	1/2144	12/18639	0.0833333333333333	0.724463619402985	0.76934834936034	0.945783551526638
GO:0016423	tRNA (guanine) methyltransferase activity	1/2144	12/18639	0.0833333333333333	0.724463619402985	0.76934834936034	0.945783551526638
GO:0017002	activin receptor activity	1/2144	12/18639	0.0833333333333333	0.724463619402985	0.76934834936034	0.945783551526638
GO:0035251	UDP-glucosyltransferase activity	1/2144	12/18639	0.0833333333333333	0.724463619402985	0.76934834936034	0.945783551526638
GO:0035497	cAMP response element binding	1/2144	12/18639	0.0833333333333333	0.724463619402985	0.76934834936034	0.945783551526638
GO:0036009	protein-glutamine N-methyltransferase activity	1/2144	12/18639	0.0833333333333333	0.724463619402985	0.76934834936034	0.945783551526638
GO:0097371	MDM2/MDM4 family protein binding	1/2144	12/18639	0.0833333333333333	0.724463619402985	0.76934834936034	0.945783551526638
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	1/2144	12/18639	0.0833333333333333	0.724463619402985	0.76934834936034	0.945783551526638
GO:0016853	isomerase activity	18/2144	180/18639	0.1	0.869356343283582	0.770187854746454	0.945884592505724
GO:0004806	triacylglycerol lipase activity	2/2144	24/18639	0.0833333333333333	0.724463619402985	0.780831092013733	0.956105237850461
GO:0050431	transforming growth factor beta binding	2/2144	24/18639	0.0833333333333333	0.724463619402985	0.780831092013733	0.956105237850461
GO:0008235	metalloexopeptidase activity	6/2144	66/18639	0.0909090909090909	0.79032394843962	0.785625529758221	0.956105237850461
GO:0016757	glycosyltransferase activity	27/2144	267/18639	0.101123595505618	0.879124392084521	0.789831140276668	0.956105237850461
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	4/2144	46/18639	0.0869565217391304	0.755962037637897	0.791082483607413	0.956105237850461
GO:0008194	UDP-glycosyltransferase activity	14/2144	145/18639	0.096551724137931	0.839378538342769	0.79409793122737	0.956105237850461
GO:0003964	RNA-directed DNA polymerase activity	1/2144	13/18639	0.0769230769230769	0.668735648679679	0.79589675430861	0.956105237850461
GO:0004465	lipoprotein lipase activity	1/2144	13/18639	0.0769230769230769	0.668735648679679	0.79589675430861	0.956105237850461
GO:0005172	vascular endothelial growth factor receptor binding	1/2144	13/18639	0.0769230769230769	0.668735648679679	0.79589675430861	0.956105237850461
GO:0008253	5'-nucleotidase activity	1/2144	13/18639	0.0769230769230769	0.668735648679679	0.79589675430861	0.956105237850461
GO:0009982	pseudouridine synthase activity	1/2144	13/18639	0.0769230769230769	0.668735648679679	0.79589675430861	0.956105237850461
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/2144	13/18639	0.0769230769230769	0.668735648679679	0.79589675430861	0.956105237850461
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/2144	13/18639	0.0769230769230769	0.668735648679679	0.79589675430861	0.956105237850461
GO:0019104	DNA N-glycosylase activity	1/2144	13/18639	0.0769230769230769	0.668735648679679	0.79589675430861	0.956105237850461
GO:0031432	titin binding	1/2144	13/18639	0.0769230769230769	0.668735648679679	0.79589675430861	0.956105237850461
GO:0031994	insulin-like growth factor I binding	1/2144	13/18639	0.0769230769230769	0.668735648679679	0.79589675430861	0.956105237850461
GO:0035673	oligopeptide transmembrane transporter activity	1/2144	13/18639	0.0769230769230769	0.668735648679679	0.79589675430861	0.956105237850461
GO:0046975	histone H3K36 methyltransferase activity	1/2144	13/18639	0.0769230769230769	0.668735648679679	0.79589675430861	0.956105237850461
GO:0070123	transforming growth factor beta receptor activity, type III	1/2144	13/18639	0.0769230769230769	0.668735648679679	0.79589675430861	0.956105237850461
GO:0070700	BMP receptor binding	1/2144	13/18639	0.0769230769230769	0.668735648679679	0.79589675430861	0.956105237850461
GO:1901338	catecholamine binding	1/2144	13/18639	0.0769230769230769	0.668735648679679	0.79589675430861	0.956105237850461
GO:0008173	RNA methyltransferase activity	6/2144	67/18639	0.0895522388059701	0.778528068612163	0.797620804462649	0.956105237850461
GO:0050840	extracellular matrix binding	6/2144	67/18639	0.0895522388059701	0.778528068612163	0.797620804462649	0.956105237850461
GO:0000030	mannosyltransferase activity	2/2144	25/18639	0.08	0.695485074626866	0.799943933990178	0.956105237850461
GO:0001848	complement binding	2/2144	25/18639	0.08	0.695485074626866	0.799943933990178	0.956105237850461
GO:0008483	transaminase activity	2/2144	25/18639	0.08	0.695485074626866	0.799943933990178	0.956105237850461
GO:0019706	protein-cysteine S-palmitoyltransferase activity	2/2144	25/18639	0.08	0.695485074626866	0.799943933990178	0.956105237850461
GO:0019707	protein-cysteine S-acyltransferase activity	2/2144	25/18639	0.08	0.695485074626866	0.799943933990178	0.956105237850461
GO:0015103	inorganic anion transmembrane transporter activity	16/2144	165/18639	0.096969696969697	0.843012211668928	0.800872388990039	0.956299822034951
GO:0003735	structural constituent of ribosome	17/2144	175/18639	0.0971428571428571	0.844517590618337	0.804246907557154	0.959155506760492
GO:0140359	ABC-type transporter activity	4/2144	47/18639	0.0851063829787234	0.739877738964751	0.804970979844402	0.959155506760492
GO:0015085	calcium ion transmembrane transporter activity	14/2144	147/18639	0.0952380952380952	0.82795842217484	0.810098352432492	0.959155506760492
GO:0015216	purine nucleotide transmembrane transporter activity	2/2144	26/18639	0.0769230769230769	0.668735648679679	0.817562098467408	0.959155506760492
GO:0030507	spectrin binding	2/2144	26/18639	0.0769230769230769	0.668735648679679	0.817562098467408	0.959155506760492
GO:0070006	metalloaminopeptidase activity	2/2144	26/18639	0.0769230769230769	0.668735648679679	0.817562098467408	0.959155506760492
GO:0120014	phospholipid transfer activity	2/2144	26/18639	0.0769230769230769	0.668735648679679	0.817562098467408	0.959155506760492
GO:0016879	ligase activity, forming carbon-nitrogen bonds	4/2144	48/18639	0.0833333333333333	0.724463619402985	0.81809881144386	0.959155506760492
GO:0032266	phosphatidylinositol-3-phosphate binding	4/2144	48/18639	0.0833333333333333	0.724463619402985	0.81809881144386	0.959155506760492
GO:0008191	metalloendopeptidase inhibitor activity	1/2144	14/18639	0.0714285714285714	0.62096881663113	0.819390653093231	0.959155506760492
GO:0008494	translation activator activity	1/2144	14/18639	0.0714285714285714	0.62096881663113	0.819390653093231	0.959155506760492
GO:0015926	glucosidase activity	1/2144	14/18639	0.0714285714285714	0.62096881663113	0.819390653093231	0.959155506760492
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/2144	14/18639	0.0714285714285714	0.62096881663113	0.819390653093231	0.959155506760492
GO:0032036	myosin heavy chain binding	1/2144	14/18639	0.0714285714285714	0.62096881663113	0.819390653093231	0.959155506760492
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	1/2144	14/18639	0.0714285714285714	0.62096881663113	0.819390653093231	0.959155506760492
GO:0046030	inositol trisphosphate phosphatase activity	1/2144	14/18639	0.0714285714285714	0.62096881663113	0.819390653093231	0.959155506760492
GO:0061783	peptidoglycan muralytic activity	1/2144	14/18639	0.0714285714285714	0.62096881663113	0.819390653093231	0.959155506760492
GO:0070742	C2H2 zinc finger domain binding	1/2144	14/18639	0.0714285714285714	0.62096881663113	0.819390653093231	0.959155506760492
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	1/2144	14/18639	0.0714285714285714	0.62096881663113	0.819390653093231	0.959155506760492
GO:0098821	BMP receptor activity	1/2144	14/18639	0.0714285714285714	0.62096881663113	0.819390653093231	0.959155506760492
GO:1901612	cardiolipin binding	1/2144	14/18639	0.0714285714285714	0.62096881663113	0.819390653093231	0.959155506760492
GO:0008028	monocarboxylic acid transmembrane transporter activity	6/2144	70/18639	0.0857142857142857	0.745162579957356	0.830498002061457	0.970755306840337
GO:0005044	scavenger receptor activity	2/2144	27/18639	0.0740740740740741	0.643967661691542	0.833776375509724	0.970755306840337
GO:0015079	potassium ion transmembrane transporter activity	15/2144	160/18639	0.09375	0.815021571828358	0.834244069549917	0.970755306840337
GO:0141108	transporter regulator activity	16/2144	170/18639	0.0941176470588235	0.818217734855136	0.836234283777695	0.970755306840337
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/2144	15/18639	0.0666666666666667	0.579570895522388	0.840181334423062	0.970755306840337
GO:0005523	tropomyosin binding	1/2144	15/18639	0.0666666666666667	0.579570895522388	0.840181334423062	0.970755306840337
GO:0008020	G protein-coupled photoreceptor activity	1/2144	15/18639	0.0666666666666667	0.579570895522388	0.840181334423062	0.970755306840337
GO:0008252	nucleotidase activity	1/2144	15/18639	0.0666666666666667	0.579570895522388	0.840181334423062	0.970755306840337
GO:0015250	water channel activity	1/2144	15/18639	0.0666666666666667	0.579570895522388	0.840181334423062	0.970755306840337
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/2144	15/18639	0.0666666666666667	0.579570895522388	0.840181334423062	0.970755306840337
GO:0017081	chloride channel regulator activity	1/2144	15/18639	0.0666666666666667	0.579570895522388	0.840181334423062	0.970755306840337
GO:0051371	muscle alpha-actinin binding	1/2144	15/18639	0.0666666666666667	0.579570895522388	0.840181334423062	0.970755306840337
GO:0140161	monocarboxylate:sodium symporter activity	1/2144	15/18639	0.0666666666666667	0.579570895522388	0.840181334423062	0.970755306840337
GO:0140776	protein-containing complex destabilizing activity	1/2144	15/18639	0.0666666666666667	0.579570895522388	0.840181334423062	0.970755306840337
GO:0000217	DNA secondary structure binding	3/2144	39/18639	0.0769230769230769	0.668735648679679	0.841980012893863	0.971036967778795
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	3/2144	39/18639	0.0769230769230769	0.668735648679679	0.841980012893863	0.971036967778795
GO:0001664	G protein-coupled receptor binding	29/2144	297/18639	0.0976430976430976	0.848866463138851	0.851057721701556	0.980600640595243
GO:0005024	transforming growth factor beta receptor activity	1/2144	16/18639	0.0625	0.543347714552239	0.858579703140682	0.985630559947346
GO:0005159	insulin-like growth factor receptor binding	1/2144	16/18639	0.0625	0.543347714552239	0.858579703140682	0.985630559947346
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1/2144	16/18639	0.0625	0.543347714552239	0.858579703140682	0.985630559947346
GO:0022841	potassium ion leak channel activity	1/2144	16/18639	0.0625	0.543347714552239	0.858579703140682	0.985630559947346
GO:0016417	S-acyltransferase activity	2/2144	29/18639	0.0689655172413793	0.599556098816263	0.862349974727178	0.989049695531906
GO:0016877	ligase activity, forming carbon-sulfur bonds	3/2144	41/18639	0.0731707317073171	0.636114397524572	0.8656686898522	0.991945131766421
GO:0005544	calcium-dependent phospholipid binding	4/2144	53/18639	0.0754716981132075	0.656117994931005	0.873208847373992	0.994090541990242
GO:0016860	intramolecular oxidoreductase activity	4/2144	53/18639	0.0754716981132075	0.656117994931005	0.873208847373992	0.994090541990242
GO:0004550	nucleoside diphosphate kinase activity	1/2144	17/18639	0.0588235294117647	0.51138608428446	0.874860920799834	0.994090541990242
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	1/2144	17/18639	0.0588235294117647	0.51138608428446	0.874860920799834	0.994090541990242
GO:0016805	dipeptidase activity	1/2144	17/18639	0.0588235294117647	0.51138608428446	0.874860920799834	0.994090541990242
GO:0019198	transmembrane receptor protein phosphatase activity	1/2144	17/18639	0.0588235294117647	0.51138608428446	0.874860920799834	0.994090541990242
GO:0045125	bioactive lipid receptor activity	1/2144	17/18639	0.0588235294117647	0.51138608428446	0.874860920799834	0.994090541990242
GO:0045236	CXCR chemokine receptor binding	1/2144	17/18639	0.0588235294117647	0.51138608428446	0.874860920799834	0.994090541990242
GO:0016769	transferase activity, transferring nitrogenous groups	2/2144	30/18639	0.0666666666666667	0.579570895522388	0.874881813535325	0.994090541990242
GO:0016859	cis-trans isomerase activity	3/2144	42/18639	0.0714285714285714	0.62096881663113	0.876295986173944	0.994090541990242
GO:0031492	nucleosomal DNA binding	3/2144	42/18639	0.0714285714285714	0.62096881663113	0.876295986173944	0.994090541990242
GO:0016247	channel regulator activity	15/2144	168/18639	0.0892857142857143	0.776211020788913	0.882294195873755	0.995247646053288
GO:0098631	cell adhesion mediator activity	6/2144	76/18639	0.0789473684210526	0.686333955223881	0.883345190387603	0.995247646053288
GO:0005245	voltage-gated calcium channel activity	3/2144	43/18639	0.0697674418604651	0.606527681360639	0.886169994222777	0.995247646053288
GO:0008200	ion channel inhibitor activity	3/2144	43/18639	0.0697674418604651	0.606527681360639	0.886169994222777	0.995247646053288
GO:0003746	translation elongation factor activity	1/2144	18/18639	0.0555555555555556	0.482975746268657	0.889268513206941	0.995247646053288
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/2144	18/18639	0.0555555555555556	0.482975746268657	0.889268513206941	0.995247646053288
GO:0005372	water transmembrane transporter activity	1/2144	18/18639	0.0555555555555556	0.482975746268657	0.889268513206941	0.995247646053288
GO:0008308	voltage-gated monoatomic anion channel activity	1/2144	18/18639	0.0555555555555556	0.482975746268657	0.889268513206941	0.995247646053288
GO:0015280	ligand-gated sodium channel activity	1/2144	18/18639	0.0555555555555556	0.482975746268657	0.889268513206941	0.995247646053288
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/2144	18/18639	0.0555555555555556	0.482975746268657	0.889268513206941	0.995247646053288
GO:0031690	adrenergic receptor binding	1/2144	18/18639	0.0555555555555556	0.482975746268657	0.889268513206941	0.995247646053288
GO:0070064	proline-rich region binding	1/2144	18/18639	0.0555555555555556	0.482975746268657	0.889268513206941	0.995247646053288
GO:0098641	cadherin binding involved in cell-cell adhesion	1/2144	18/18639	0.0555555555555556	0.482975746268657	0.889268513206941	0.995247646053288
GO:0099602	neurotransmitter receptor regulator activity	1/2144	18/18639	0.0555555555555556	0.482975746268657	0.889268513206941	0.995247646053288
GO:1901611	phosphatidylglycerol binding	1/2144	18/18639	0.0555555555555556	0.482975746268657	0.889268513206941	0.995247646053288
GO:0098632	cell-cell adhesion mediator activity	4/2144	55/18639	0.0727272727272727	0.632259158751696	0.890843783908226	0.996118071711168
GO:0099106	ion channel regulator activity	14/2144	160/18639	0.0875	0.760686800373134	0.892484197705354	0.997059716398915
GO:0042910	xenobiotic transmembrane transporter activity	2/2144	32/18639	0.0625	0.543347714552239	0.896843145387705	0.998777029835069
GO:0005229	intracellularly calcium-gated chloride channel activity	1/2144	19/18639	0.0526315789473684	0.457555970149254	0.902018006128069	0.998777029835069
GO:0008301	DNA binding, bending	1/2144	19/18639	0.0526315789473684	0.457555970149254	0.902018006128069	0.998777029835069
GO:0008381	mechanosensitive monoatomic ion channel activity	1/2144	19/18639	0.0526315789473684	0.457555970149254	0.902018006128069	0.998777029835069
GO:0022840	leak channel activity	1/2144	19/18639	0.0526315789473684	0.457555970149254	0.902018006128069	0.998777029835069
GO:0022842	narrow pore channel activity	1/2144	19/18639	0.0526315789473684	0.457555970149254	0.902018006128069	0.998777029835069
GO:0030506	ankyrin binding	1/2144	19/18639	0.0526315789473684	0.457555970149254	0.902018006128069	0.998777029835069
GO:0042577	lipid phosphatase activity	1/2144	19/18639	0.0526315789473684	0.457555970149254	0.902018006128069	0.998777029835069
GO:0046527	glucosyltransferase activity	1/2144	19/18639	0.0526315789473684	0.457555970149254	0.902018006128069	0.998777029835069
GO:0141147	intracellularly calcium-gated channel activity	1/2144	19/18639	0.0526315789473684	0.457555970149254	0.902018006128069	0.998777029835069
GO:0042923	neuropeptide binding	2/2144	33/18639	0.0606060606060606	0.52688263229308	0.906424612676262	0.999999999975104
GO:0000049	tRNA binding	6/2144	80/18639	0.075	0.652017257462687	0.910239330810631	0.999999999975104
GO:0072341	modified amino acid binding	7/2144	91/18639	0.0769230769230769	0.668735648679679	0.910907212141318	0.999999999975104
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	1/2144	20/18639	0.05	0.434678171641791	0.913300143338671	0.999999999975104
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/2144	20/18639	0.05	0.434678171641791	0.913300143338671	0.999999999975104
GO:0005326	neurotransmitter transmembrane transporter activity	1/2144	20/18639	0.05	0.434678171641791	0.913300143338671	0.999999999975104
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/2144	20/18639	0.05	0.434678171641791	0.913300143338671	0.999999999975104
GO:0140664	ATP-dependent DNA damage sensor activity	1/2144	20/18639	0.05	0.434678171641791	0.913300143338671	0.999999999975104
GO:0140939	histone H4 methyltransferase activity	1/2144	20/18639	0.05	0.434678171641791	0.913300143338671	0.999999999975104
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	2/2144	34/18639	0.0588235294117647	0.51138608428446	0.9151679719345	0.999999999975104
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	2/2144	34/18639	0.0588235294117647	0.51138608428446	0.9151679719345	0.999999999975104
GO:0005253	monoatomic anion channel activity	8/2144	103/18639	0.0776699029126214	0.675228227793073	0.917480721286055	0.999999999975104
GO:0016758	hexosyltransferase activity	17/2144	197/18639	0.0862944162436548	0.750205981513751	0.921340092772305	0.999999999975104
GO:1904047	S-adenosyl-L-methionine binding	1/2144	21/18639	0.0476190476190476	0.41397921108742	0.923283734975273	0.999999999975104
GO:0004714	transmembrane receptor protein tyrosine kinase activity	4/2144	60/18639	0.0666666666666667	0.579570895522388	0.92583103414755	0.999999999975104
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	2/2144	36/18639	0.0555555555555556	0.482975746268657	0.930400010641583	0.999999999975104
GO:0016409	palmitoyltransferase activity	2/2144	36/18639	0.0555555555555556	0.482975746268657	0.930400010641583	0.999999999975104
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	2/2144	36/18639	0.0555555555555556	0.482975746268657	0.930400010641583	0.999999999975104
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	2/2144	36/18639	0.0555555555555556	0.482975746268657	0.930400010641583	0.999999999975104
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	2/2144	36/18639	0.0555555555555556	0.482975746268657	0.930400010641583	0.999999999975104
GO:0030021	extracellular matrix structural constituent conferring compression resistance	1/2144	22/18639	0.0454545454545455	0.39516197421981	0.932118178643391	0.999999999975104
GO:0034062	5'-3' RNA polymerase activity	1/2144	22/18639	0.0454545454545455	0.39516197421981	0.932118178643391	0.999999999975104
GO:0097747	RNA polymerase activity	1/2144	22/18639	0.0454545454545455	0.39516197421981	0.932118178643391	0.999999999975104
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	15/2144	181/18639	0.0828729281767956	0.720461057969819	0.936040533777132	0.999999999975104
GO:0022853	active monoatomic ion transmembrane transporter activity	9/2144	118/18639	0.076271186440678	0.663068397419681	0.936127740328323	0.999999999975104
GO:0019842	vitamin binding	12/2144	150/18639	0.08	0.695485074626866	0.936563742873299	0.999999999975104
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/2144	23/18639	0.0434782608695652	0.377981018818949	0.939935690862791	0.999999999975104
GO:0005212	structural constituent of eye lens	1/2144	23/18639	0.0434782608695652	0.377981018818949	0.939935690862791	0.999999999975104
GO:0008171	O-methyltransferase activity	1/2144	23/18639	0.0434782608695652	0.377981018818949	0.939935690862791	0.999999999975104
GO:0008083	growth factor activity	13/2144	162/18639	0.0802469135802469	0.697631633499171	0.941506088923579	0.999999999975104
GO:0005021	vascular endothelial growth factor receptor activity	3/2144	51/18639	0.0588235294117647	0.51138608428446	0.942911074697744	0.999999999975104
GO:0016597	amino acid binding	3/2144	51/18639	0.0588235294117647	0.51138608428446	0.942911074697744	0.999999999975104
GO:0046906	tetrapyrrole binding	12/2144	152/18639	0.0789473684210526	0.686333955223881	0.943088213869173	0.999999999975104
GO:0005540	hyaluronic acid binding	1/2144	24/18639	0.0416666666666667	0.362231809701493	0.946853282117098	0.999999999975104
GO:0140612	DNA damage sensor activity	1/2144	24/18639	0.0416666666666667	0.362231809701493	0.946853282117098	0.999999999975104
GO:0005506	iron ion binding	12/2144	154/18639	0.0779220779220779	0.67742052723396	0.9490225118403	0.999999999975104
GO:0017046	peptide hormone binding	3/2144	53/18639	0.0566037735849057	0.492088496198254	0.952246706077021	0.999999999975104
GO:0015399	primary active transmembrane transporter activity	13/2144	166/18639	0.0783132530120482	0.680821232691962	0.952789803487817	0.999999999975104
GO:0005251	delayed rectifier potassium channel activity	1/2144	25/18639	0.04	0.347742537313433	0.952974504955719	0.999999999975104
GO:0015271	outward rectifier potassium channel activity	1/2144	25/18639	0.04	0.347742537313433	0.952974504955719	0.999999999975104
GO:0017171	serine hydrolase activity	16/2144	198/18639	0.0808080808080808	0.702510176390773	0.954096567619101	0.999999999975104
GO:0019199	transmembrane receptor protein kinase activity	5/2144	78/18639	0.0641025641025641	0.557279707233065	0.954187886409119	0.999999999975104
GO:0050661	NADP binding	3/2144	54/18639	0.0555555555555556	0.482975746268657	0.956360420974291	0.999999999975104
GO:0099094	ligand-gated monoatomic cation channel activity	10/2144	136/18639	0.0735294117647059	0.639232605355575	0.958497290877881	0.999999999975104
GO:0005539	glycosaminoglycan binding	20/2144	242/18639	0.0826446280991736	0.718476316763291	0.959689657636321	0.999999999975104
GO:0004520	DNA endonuclease activity	2/2144	42/18639	0.0476190476190476	0.41397921108742	0.962022843169343	0.999999999975104
GO:0005104	fibroblast growth factor receptor binding	1/2144	27/18639	0.037037037037037	0.321983830845771	0.963183871434695	0.999999999975104
GO:0008395	steroid hydroxylase activity	1/2144	27/18639	0.037037037037037	0.321983830845771	0.963183871434695	0.999999999975104
GO:0015252	proton channel activity	1/2144	27/18639	0.037037037037037	0.321983830845771	0.963183871434695	0.999999999975104
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	2/2144	43/18639	0.0465116279069767	0.404351787573759	0.965722982142346	0.999999999975104
GO:0008236	serine-type peptidase activity	15/2144	194/18639	0.077319587628866	0.672182739652254	0.967294417268165	0.999999999975104
GO:0051537	2 iron, 2 sulfur cluster binding	1/2144	28/18639	0.0357142857142857	0.310484408315565	0.967424886889456	0.999999999975104
GO:0005254	chloride channel activity	5/2144	83/18639	0.0602409638554217	0.523708640532278	0.968947791464576	0.999999999975104
GO:0140299	molecular sensor activity	4/2144	71/18639	0.0563380281690141	0.489778221568215	0.969901766497724	0.999999999975104
GO:0005262	calcium channel activity	9/2144	131/18639	0.0687022900763359	0.597267716759713	0.971789339716136	0.999999999975104
GO:0004252	serine-type endopeptidase activity	13/2144	176/18639	0.0738636363636364	0.642138208107191	0.973063584714586	0.999999999975104
GO:0016651	oxidoreductase activity, acting on NAD(P)H	5/2144	88/18639	0.0568181818181818	0.493952467774762	0.979195973732951	0.999999999975104
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/2144	32/18639	0.03125	0.271673857276119	0.980036034719569	0.999999999975104
GO:0008201	heparin binding	12/2144	172/18639	0.0697674418604651	0.606527681360639	0.982294825984589	0.999999999975104
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	1/2144	33/18639	0.0303030303030303	0.26344131614654	0.982336391658422	0.999999999975104
GO:0019825	oxygen binding	1/2144	34/18639	0.0294117647058824	0.25569304214223	0.984371798316723	0.999999999975104
GO:0051427	hormone receptor binding	1/2144	34/18639	0.0294117647058824	0.25569304214223	0.984371798316723	0.999999999975104
GO:0005010	insulin-like growth factor receptor activity	2/2144	51/18639	0.0392156862745098	0.34092405618964	0.98510106465087	0.999999999975104
GO:0016229	steroid dehydrogenase activity	1/2144	35/18639	0.0285714285714286	0.248387526652452	0.9861727585107	0.999999999975104
GO:0020037	heme binding	9/2144	142/18639	0.0633802816901408	0.551000499264242	0.986593687118633	0.999999999975104
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	2/2144	52/18639	0.0384615384615385	0.334367824339839	0.98659419263617	0.999999999975104
GO:0016500	protein-hormone receptor activity	3/2144	67/18639	0.0447761194029851	0.389264034306082	0.987023561066836	0.999999999975104
GO:0004033	aldo-keto reductase (NADPH) activity	1/2144	36/18639	0.0277777777777778	0.241487873134328	0.987766265592675	0.999999999975104
GO:0022829	wide pore channel activity	1/2144	37/18639	0.027027027027027	0.234961173860428	0.989176206278011	0.999999999975104
GO:0030280	structural constituent of skin epidermis	1/2144	37/18639	0.027027027027027	0.234961173860428	0.989176206278011	0.999999999975104
GO:0005109	frizzled binding	1/2144	38/18639	0.0263157894736842	0.228777985074627	0.990423718036959	0.999999999975104
GO:0005267	potassium channel activity	7/2144	124/18639	0.0564516129032258	0.490765677660087	0.991396033169112	0.999999999975104
GO:0071855	neuropeptide receptor binding	1/2144	40/18639	0.025	0.217339085820896	0.992504119821268	0.999999999975104
GO:1901681	sulfur compound binding	20/2144	275/18639	0.0727272727272727	0.632259158751696	0.992609916738128	0.999999999975104
GO:0008227	G protein-coupled amine receptor activity	1/2144	41/18639	0.024390243902439	0.212038132508191	0.993368207519703	0.999999999975104
GO:0009055	electron transfer activity	6/2144	116/18639	0.0517241379310345	0.449667074112198	0.994056400351658	0.999999999975104
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	2/2144	60/18639	0.0333333333333333	0.289785447761194	0.994295607157065	0.999999999975104
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/2144	46/18639	0.0217391304347826	0.188990509409474	0.996405597208632	0.999999999975104
GO:0099095	ligand-gated monoatomic anion channel activity	1/2144	47/18639	0.0212765957446809	0.184969434741188	0.996820075753498	0.999999999975104
GO:0008188	neuropeptide receptor activity	1/2144	48/18639	0.0208333333333333	0.181115904850746	0.997186779582268	0.999999999975104
GO:0140101	catalytic activity, acting on a tRNA	7/2144	139/18639	0.0503597122302158	0.437805352732739	0.997400315427617	0.999999999975104
GO:0005004	GPI-linked ephrin receptor activity	1/2144	49/18639	0.0204081632653061	0.177419661894609	0.997511213156343	0.999999999975104
GO:0005008	hepatocyte growth factor receptor activity	1/2144	49/18639	0.0204081632653061	0.177419661894609	0.997511213156343	0.999999999975104
GO:0005009	insulin receptor activity	1/2144	49/18639	0.0204081632653061	0.177419661894609	0.997511213156343	0.999999999975104
GO:0005011	macrophage colony-stimulating factor receptor activity	1/2144	49/18639	0.0204081632653061	0.177419661894609	0.997511213156343	0.999999999975104
GO:0005018	platelet-derived growth factor alpha-receptor activity	1/2144	49/18639	0.0204081632653061	0.177419661894609	0.997511213156343	0.999999999975104
GO:0005020	stem cell factor receptor activity	1/2144	49/18639	0.0204081632653061	0.177419661894609	0.997511213156343	0.999999999975104
GO:0008288	boss receptor activity	1/2144	49/18639	0.0204081632653061	0.177419661894609	0.997511213156343	0.999999999975104
GO:0036332	placental growth factor receptor activity	1/2144	49/18639	0.0204081632653061	0.177419661894609	0.997511213156343	0.999999999975104
GO:0038062	protein tyrosine kinase collagen receptor activity	1/2144	49/18639	0.0204081632653061	0.177419661894609	0.997511213156343	0.999999999975104
GO:0060175	brain-derived neurotrophic factor receptor activity	1/2144	49/18639	0.0204081632653061	0.177419661894609	0.997511213156343	0.999999999975104
GO:0005006	epidermal growth factor receptor activity	1/2144	50/18639	0.02	0.173871268656716	0.997798246991351	0.999999999975104
GO:0005007	fibroblast growth factor receptor activity	1/2144	50/18639	0.02	0.173871268656716	0.997798246991351	0.999999999975104
GO:0005017	platelet-derived growth factor receptor activity	1/2144	50/18639	0.02	0.173871268656716	0.997798246991351	0.999999999975104
GO:0005019	platelet-derived growth factor beta-receptor activity	1/2144	50/18639	0.02	0.173871268656716	0.997798246991351	0.999999999975104
GO:0001653	peptide receptor activity	6/2144	128/18639	0.046875	0.407510785914179	0.997839204055683	0.999999999975104
GO:0005030	neurotrophin receptor activity	1/2144	51/18639	0.0196078431372549	0.17046202809482	0.99805219063816	0.999999999975104
GO:0005272	sodium channel activity	1/2144	51/18639	0.0196078431372549	0.17046202809482	0.99805219063816	0.999999999975104
GO:0005003	ephrin receptor activity	1/2144	53/18639	0.0188679245283019	0.164029498732751	0.998475620811271	0.999999999975104
GO:0005005	transmembrane-ephrin receptor activity	1/2144	53/18639	0.0188679245283019	0.164029498732751	0.998475620811271	0.999999999975104
GO:0038064	collagen receptor activity	1/2144	53/18639	0.0188679245283019	0.164029498732751	0.998475620811271	0.999999999975104
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	2/2144	73/18639	0.0273972602739726	0.238179820077694	0.998618603723516	0.999999999975104
GO:0015276	ligand-gated monoatomic ion channel activity	10/2144	186/18639	0.0537634408602151	0.467395883485797	0.998701659350729	0.999999999975104
GO:0022832	voltage-gated channel activity	9/2144	175/18639	0.0514285714285714	0.447097547974414	0.998858946781277	0.999999999975104
GO:0022834	ligand-gated channel activity	10/2144	188/18639	0.0531914893617021	0.462423586852969	0.998886283898291	0.999999999975104
GO:0008528	G protein-coupled peptide receptor activity	5/2144	122/18639	0.040983606557377	0.356293583312943	0.998924152213823	0.999999999975104
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	5/2144	122/18639	0.040983606557377	0.356293583312943	0.998924152213823	0.999999999975104
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	1/2144	58/18639	0.0172413793103448	0.149889024704066	0.999174140647517	0.999999999975104
GO:0016874	ligase activity	8/2144	167/18639	0.0479041916167665	0.416458128519081	0.999238753320662	0.999999999975104
GO:0005249	voltage-gated potassium channel activity	3/2144	98/18639	0.0306122448979592	0.266129492841913	0.99942125029691	0.999999999975104
GO:0022843	voltage-gated monoatomic cation channel activity	6/2144	143/18639	0.041958041958042	0.364764899279825	0.999422350001205	0.999999999975104
GO:0005244	voltage-gated monoatomic ion channel activity	8/2144	173/18639	0.046242774566474	0.402014494003969	0.999538862370205	0.999999999975104
GO:0005179	hormone activity	5/2144	132/18639	0.0378787878787879	0.329301645183175	0.999576259583576	0.999999999975104
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	5/2144	132/18639	0.0378787878787879	0.329301645183175	0.999576259583576	0.999999999975104
GO:0004497	monooxygenase activity	3/2144	106/18639	0.0283018867924528	0.246044248099127	0.999749281548193	0.999999999975104
GO:0005261	monoatomic cation channel activity	20/2144	341/18639	0.0586510263929619	0.509886418348142	0.999879591266731	0.999999999975104
GO:0005216	monoatomic ion channel activity	27/2144	448/18639	0.0602678571428571	0.523942439032516	0.999976062265801	0.999999999975104
GO:0005201	extracellular matrix structural constituent	5/2144	168/18639	0.0297619047619048	0.258737006929637	0.999987340125446	0.999999999975104
GO:0022836	gated channel activity	15/2144	318/18639	0.0471698113207547	0.410073746831878	0.999993604409786	0.999999999975104
GO:0045182	translation regulator activity	10/2144	356/18639	0.0280898876404494	0.244201220023478	0.999999999708018	0.999999999975104
GO:0030371	translation repressor activity	7/2144	329/18639	0.0212765957446809	0.184969434741188	0.999999999975104	0.999999999975104