ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0008201	heparin binding	21/249	172/18639	0.122093023255814	9.13932474082376	1.52038727465951e-14	9.48721659387533e-12
GO:1901681	sulfur compound binding	24/249	275/18639	0.0872727272727273	6.53283680175246	3.57216035797874e-13	1.11451403168937e-10
GO:0005539	glycosaminoglycan binding	22/249	242/18639	0.0909090909090909	6.80503833515882	1.58104288000391e-12	3.28856919040813e-10
GO:0019838	growth factor binding	15/249	136/18639	0.110294117647059	8.25611268603827	4.15228575632876e-10	6.47756577987287e-08
GO:0005201	extracellular matrix structural constituent	15/249	168/18639	0.0892857142857143	6.68351979345955	7.91579661714753e-09	9.87891417820012e-07
GO:0001968	fibronectin binding	7/249	30/18639	0.233333333333333	17.466265060241	1.09323723153934e-07	1.13696672080091e-05
GO:0005158	insulin receptor binding	6/249	23/18639	0.260869565217391	19.5275013095862	4.46559902079853e-07	3.75974391777132e-05
GO:0031994	insulin-like growth factor I binding	5/249	13/18639	0.384615384615385	28.790546802595	4.82018450996323e-07	3.75974391777132e-05
GO:0003779	actin binding	20/249	443/18639	0.0451467268623025	3.37947727705404	2.28565925857548e-06	0.000158472375261233
GO:0005520	insulin-like growth factor binding	5/249	19/18639	0.263157894736842	19.6987951807229	4.07832927499637e-06	0.000254487746759773
GO:0004866	endopeptidase inhibitor activity	11/249	161/18639	0.0683229813664596	5.11434558108209	1.1083161385644e-05	0.000628717518603804
GO:0005543	phospholipid binding	20/249	497/18639	0.0402414486921529	3.0122906111367	1.26067597366196e-05	0.000634765819610503
GO:0004857	enzyme inhibitor activity	18/249	416/18639	0.0432692307692308	3.23893651529194	1.32242879085521e-05	0.000634765819610503
GO:0030414	peptidase inhibitor activity	11/249	169/18639	0.0650887573964497	4.87224638197761	1.74995622435548e-05	0.000779980488569873
GO:0043560	insulin receptor substrate binding	4/249	13/18639	0.307692307692308	23.032437442076	2.02197989916152e-05	0.000833561297850862
GO:0043548	phosphatidylinositol 3-kinase binding	5/249	26/18639	0.192307692307692	14.3952734012975	2.13733666115606e-05	0.000833561297850862
GO:0005161	platelet-derived growth factor receptor binding	4/249	14/18639	0.285714285714286	21.3872633390706	2.80110616162714e-05	0.00102817073226784
GO:0050840	extracellular matrix binding	7/249	67/18639	0.104477611940299	7.82071569861536	3.06722064925503e-05	0.00106330315840841
GO:0061135	endopeptidase regulator activity	11/249	184/18639	0.0597826086956522	4.47505238344683	3.84699673709941e-05	0.00126325840581058
GO:0004867	serine-type endopeptidase inhibitor activity	8/249	95/18639	0.0842105263157895	6.30361445783133	4.04890514682877e-05	0.00126325840581058
GO:0070325	lipoprotein particle receptor binding	5/249	31/18639	0.161290322580645	12.0734551107656	5.22791406538846e-05	0.00155343732228686
GO:0061134	peptidase regulator activity	12/249	226/18639	0.0530973451327434	3.97462416035825	5.48795743019198e-05	0.00155658428929082
GO:0002020	protease binding	9/249	136/18639	0.0661764705882353	4.95366761162296	8.99530731353919e-05	0.00244046598419498
GO:0004222	metalloendopeptidase activity	8/249	110/18639	0.0727272727272727	5.44403066812705	0.000114951140584918	0.00298872965520786
GO:0030020	extracellular matrix structural constituent conferring tensile strength	5/249	44/18639	0.113636363636364	8.50629791894852	0.000290105269607403	0.00724102752940077
GO:0004896	cytokine receptor activity	7/249	96/18639	0.0729166666666667	5.4582078313253	0.000302904983668225	0.00726971960803741
GO:0005178	integrin binding	9/249	161/18639	0.0559006211180124	4.18446456633989	0.000321440410036326	0.00742884503195065
GO:0004175	endopeptidase activity	15/249	405/18639	0.037037037037037	2.77242302543507	0.000379620170741516	0.00846010666223951
GO:0005518	collagen binding	6/249	72/18639	0.0833333333333333	6.23795180722892	0.000400260145024274	0.00861249415500507
GO:0005010	insulin-like growth factor receptor activity	5/249	51/18639	0.0980392156862745	7.33876683203402	0.000581652350465062	0.0119755149510215
GO:0004713	protein tyrosine kinase activity	8/249	140/18639	0.0571428571428571	4.27745266781411	0.00059493744147703	0.0119755149510215
GO:0019199	transmembrane receptor protein kinase activity	6/249	78/18639	0.0769230769230769	5.758109360519	0.000615691348372386	0.0120059812932615
GO:0017046	peptide hormone binding	5/249	53/18639	0.0943396226415094	7.06183223459877	0.000695346872530065	0.0131457595684491
GO:0019955	cytokine binding	8/249	144/18639	0.0555555555555556	4.15863453815261	0.000716275361101393	0.0131457595684491
GO:0015485	cholesterol binding	5/249	54/18639	0.0925925925925926	6.93105756358768	0.000758054342105097	0.0135150259849594
GO:0008237	metallopeptidase activity	9/249	184/18639	0.0489130434782609	3.66140649554741	0.000844956947159216	0.0144498666363783
GO:0019209	kinase activator activity	8/249	148/18639	0.0540540540540541	4.04623901009443	0.000856802989657047	0.0144498666363783
GO:0051371	muscle alpha-actinin binding	3/249	15/18639	0.2	14.9710843373494	0.000951676837377267	0.0156275354348267
GO:0016209	antioxidant activity	6/249	86/18639	0.0697674418604651	5.22247128047072	0.00103154677300271	0.0165047483680434
GO:0005159	insulin-like growth factor receptor binding	3/249	16/18639	0.1875	14.0353915662651	0.00115978656943582	0.0176513858372672
GO:0055102	lipase inhibitor activity	3/249	16/18639	0.1875	14.0353915662651	0.00115978656943582	0.0176513858372672
GO:0004714	transmembrane receptor protein tyrosine kinase activity	5/249	60/18639	0.0833333333333333	6.23795180722892	0.00122692879987634	0.0178081961498187
GO:0005126	cytokine receptor binding	11/249	275/18639	0.04	2.99421686746988	0.00122716736288815	0.0178081961498187
GO:0043394	proteoglycan binding	4/249	37/18639	0.108108108108108	8.09247802018886	0.00145222609137147	0.0205952063867226
GO:0008083	growth factor activity	8/249	162/18639	0.0493827160493827	3.69656403391343	0.00153176654419453	0.0212404960794974
GO:0019207	kinase regulator activity	11/249	287/18639	0.0383275261324042	2.86902313085093	0.00172276436497345	0.0233696731248572
GO:0033218	amide binding	10/249	247/18639	0.0404858299595142	3.03058387395737	0.0018545373500581	0.0246219426901331
GO:0032934	sterol binding	5/249	68/18639	0.0735294117647059	5.50407512402551	0.00214823118520331	0.0279270054076431
GO:0030295	protein kinase activator activity	7/249	139/18639	0.0503597122302158	3.76969749501604	0.00267532259990957	0.0333880260468714
GO:0070851	growth factor receptor binding	7/249	139/18639	0.0503597122302158	3.76969749501604	0.00267532259990957	0.0333880260468714
GO:0098631	cell adhesion mediator activity	5/249	76/18639	0.0657894736842105	4.92469879518072	0.00349345226652225	0.0418229913834194
GO:0005004	GPI-linked ephrin receptor activity	4/249	49/18639	0.0816326530612245	6.11064666830588	0.00411212597737928	0.0418229913834194
GO:0005008	hepatocyte growth factor receptor activity	4/249	49/18639	0.0816326530612245	6.11064666830588	0.00411212597737928	0.0418229913834194
GO:0005009	insulin receptor activity	4/249	49/18639	0.0816326530612245	6.11064666830588	0.00411212597737928	0.0418229913834194
GO:0005011	macrophage colony-stimulating factor receptor activity	4/249	49/18639	0.0816326530612245	6.11064666830588	0.00411212597737928	0.0418229913834194
GO:0005018	platelet-derived growth factor alpha-receptor activity	4/249	49/18639	0.0816326530612245	6.11064666830588	0.00411212597737928	0.0418229913834194
GO:0005020	stem cell factor receptor activity	4/249	49/18639	0.0816326530612245	6.11064666830588	0.00411212597737928	0.0418229913834194
GO:0008288	boss receptor activity	4/249	49/18639	0.0816326530612245	6.11064666830588	0.00411212597737928	0.0418229913834194
GO:0036332	placental growth factor receptor activity	4/249	49/18639	0.0816326530612245	6.11064666830588	0.00411212597737928	0.0418229913834194
GO:0038062	protein tyrosine kinase collagen receptor activity	4/249	49/18639	0.0816326530612245	6.11064666830588	0.00411212597737928	0.0418229913834194
GO:0060175	brain-derived neurotrophic factor receptor activity	4/249	49/18639	0.0816326530612245	6.11064666830588	0.00411212597737928	0.0418229913834194
GO:0120020	cholesterol transfer activity	3/249	25/18639	0.12	8.98265060240964	0.00435965300292959	0.0418229913834194
GO:0005006	epidermal growth factor receptor activity	4/249	50/18639	0.08	5.98843373493976	0.00442358562709243	0.0418229913834194
GO:0005007	fibroblast growth factor receptor activity	4/249	50/18639	0.08	5.98843373493976	0.00442358562709243	0.0418229913834194
GO:0005017	platelet-derived growth factor receptor activity	4/249	50/18639	0.08	5.98843373493976	0.00442358562709243	0.0418229913834194
GO:0005019	platelet-derived growth factor beta-receptor activity	4/249	50/18639	0.08	5.98843373493976	0.00442358562709243	0.0418229913834194
GO:0005021	vascular endothelial growth factor receptor activity	4/249	51/18639	0.0784313725490196	5.87101346562721	0.00475055867191179	0.0435933619304847
GO:0005030	neurotrophin receptor activity	4/249	51/18639	0.0784313725490196	5.87101346562721	0.00475055867191179	0.0435933619304847
GO:0140375	immune receptor activity	7/249	156/18639	0.0448717948717949	3.35889712696942	0.00504773567411167	0.04540392028372
GO:0030159	signaling receptor complex adaptor activity	4/249	52/18639	0.0769230769230769	5.758109360519	0.00509338849336603	0.04540392028372
GO:0005003	ephrin receptor activity	4/249	53/18639	0.0754716981132075	5.64946578767902	0.00545241229914855	0.0466069215708041
GO:0005005	transmembrane-ephrin receptor activity	4/249	53/18639	0.0754716981132075	5.64946578767902	0.00545241229914855	0.0466069215708041
GO:0038064	collagen receptor activity	4/249	53/18639	0.0754716981132075	5.64946578767902	0.00545241229914855	0.0466069215708041
GO:0036408	histone H3K14 acetyltransferase activity	3/249	28/18639	0.107142857142857	8.02022375215146	0.00602972011778713	0.0501672713799889
GO:0051393	alpha-actinin binding	3/249	28/18639	0.107142857142857	8.02022375215146	0.00602972011778713	0.0501672713799889
GO:0098632	cell-cell adhesion mediator activity	4/249	55/18639	0.0727272727272727	5.44403066812705	0.00622035871349719	0.0510724189108191
GO:0010484	histone H3 acetyltransferase activity	3/249	29/18639	0.103448275862069	7.7436643124221	0.00665994445066147	0.0532795556052918
GO:0043236	laminin binding	3/249	29/18639	0.103448275862069	7.7436643124221	0.00665994445066147	0.0532795556052918
GO:0043995	histone H4K5 acetyltransferase activity	3/249	30/18639	0.1	7.4855421686747	0.00732790422899296	0.0563179124297187
GO:0043996	histone H4K8 acetyltransferase activity	3/249	30/18639	0.1	7.4855421686747	0.00732790422899296	0.0563179124297187
GO:0043997	histone H4K12 acetyltransferase activity	3/249	30/18639	0.1	7.4855421686747	0.00732790422899296	0.0563179124297187
GO:0072341	modified amino acid binding	5/249	91/18639	0.0549450549450549	4.11293525751357	0.00748819162281481	0.0563179124297187
GO:0019887	protein kinase regulator activity	9/249	255/18639	0.0352941176470588	2.64195605953225	0.00749100437767092	0.0563179124297187
GO:0043178	alcohol binding	5/249	92/18639	0.0543478260869565	4.06822943949712	0.00783439758806123	0.0581983820827405
GO:0001786	phosphatidylserine binding	4/249	59/18639	0.0677966101694915	5.07494384316929	0.00796468990917109	0.0582940413206273
GO:0047499	calcium-independent phospholipase A2 activity	3/249	31/18639	0.0967741935483871	7.24407306645939	0.00803411466918902	0.0582940413206273
GO:0016410	N-acyltransferase activity	5/249	94/18639	0.0531914893617021	3.98167136631633	0.00855990215603191	0.0593082302538767
GO:0042562	hormone binding	5/249	94/18639	0.0531914893617021	3.98167136631633	0.00855990215603191	0.0593082302538767
GO:0047498	calcium-dependent phospholipase A2 activity	3/249	32/18639	0.09375	7.01769578313253	0.00877904921567492	0.0593082302538767
GO:0071813	lipoprotein particle binding	3/249	32/18639	0.09375	7.01769578313253	0.00877904921567492	0.0593082302538767
GO:0071814	protein-lipid complex binding	3/249	32/18639	0.09375	7.01769578313253	0.00877904921567492	0.0593082302538767
GO:0120015	sterol transfer activity	3/249	32/18639	0.09375	7.01769578313253	0.00877904921567492	0.0593082302538767
GO:0003953	NAD+ nucleosidase activity	2/249	11/18639	0.181818181818182	13.6100766703176	0.00902929787518956	0.0593082302538767
GO:0048185	activin binding	2/249	11/18639	0.181818181818182	13.6100766703176	0.00902929787518956	0.0593082302538767
GO:0048407	platelet-derived growth factor binding	2/249	11/18639	0.181818181818182	13.6100766703176	0.00902929787518956	0.0593082302538767
GO:0030296	protein tyrosine kinase activator activity	3/249	33/18639	0.0909090909090909	6.80503833515882	0.00956314083470161	0.0621604154255604
GO:0005527	macrolide binding	2/249	12/18639	0.166666666666667	12.4759036144578	0.0107403567314255	0.0683875775551991
GO:0035014	phosphatidylinositol 3-kinase regulator activity	2/249	12/18639	0.166666666666667	12.4759036144578	0.0107403567314255	0.0683875775551991
GO:0004623	phospholipase A2 activity	3/249	35/18639	0.0857142857142857	6.41617900172117	0.0112503323149085	0.0702020736450293
GO:0010485	histone H4 acetyltransferase activity	3/249	35/18639	0.0857142857142857	6.41617900172117	0.0112503323149085	0.0702020736450293
GO:0016500	protein-hormone receptor activity	4/249	67/18639	0.0597014925373134	4.46898039920878	0.0123518723988706	0.0762262318333137
GO:0008035	high-density lipoprotein particle binding	2/249	13/18639	0.153846153846154	11.516218721038	0.0125822145494091	0.0762262318333137
GO:0039706	co-receptor binding	2/249	13/18639	0.153846153846154	11.516218721038	0.0125822145494091	0.0762262318333137
GO:0042805	actinin binding	3/249	37/18639	0.0810810810810811	6.06935851514165	0.0130983905438234	0.0785903432629404
GO:0008080	N-acetyltransferase activity	4/249	69/18639	0.0579710144927536	4.33944473546359	0.0136479595326353	0.0811078737939469
GO:0008191	metalloendopeptidase inhibitor activity	2/249	14/18639	0.142857142857143	10.6936316695353	0.0145511001702142	0.0848056254447942
GO:0008195	phosphatidate phosphatase activity	2/249	14/18639	0.142857142857143	10.6936316695353	0.0145511001702142	0.0848056254447942
GO:0045296	cadherin binding	10/249	334/18639	0.029940119760479	2.24118029002237	0.014677896711599	0.0848056254447942
GO:0005496	steroid binding	5/249	108/18639	0.0462962962962963	3.46552878179384	0.0149755762120197	0.0857317390486263
GO:0004402	histone acetyltransferase activity	3/249	42/18639	0.0714285714285714	5.34681583476764	0.0184350122295018	0.1038750768828
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	2/249	16/18639	0.125	9.35692771084337	0.0188552523695055	0.1038750768828
GO:0022858	alanine transmembrane transporter activity	2/249	16/18639	0.125	9.35692771084337	0.0188552523695055	0.1038750768828
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/249	16/18639	0.125	9.35692771084337	0.0188552523695055	0.1038750768828
GO:0035401	histone H3Y41 kinase activity	5/249	115/18639	0.0434782608695652	3.25458355159769	0.0191436439767982	0.1038750768828
GO:0140801	histone H2AXY142 kinase activity	5/249	115/18639	0.0434782608695652	3.25458355159769	0.0191436439767982	0.1038750768828
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	2/249	17/18639	0.117647058823529	8.80652019844082	0.0211833547485858	0.112020452229809
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/249	17/18639	0.117647058823529	8.80652019844082	0.0211833547485858	0.112020452229809
GO:0046965	nuclear retinoid X receptor binding	2/249	17/18639	0.117647058823529	8.80652019844082	0.0211833547485858	0.112020452229809
GO:0003713	transcription coactivator activity	8/249	256/18639	0.03125	2.33923192771084	0.022071487823407	0.115736205057193
GO:0015101	organic cation transmembrane transporter activity	4/249	81/18639	0.0493827160493827	3.69656403391343	0.0232270376062048	0.120780595552265
GO:0098641	cadherin binding involved in cell-cell adhesion	2/249	18/18639	0.111111111111111	8.31726907630522	0.0236241538728245	0.121830347244979
GO:0061733	protein-lysine-acetyltransferase activity	3/249	47/18639	0.0638297872340425	4.77800563957959	0.0248083291337937	0.126888503110552
GO:0030165	PDZ domain binding	4/249	83/18639	0.0481927710843374	3.60749020177094	0.0251360063901247	0.127519251930389
GO:0042577	lipid phosphatase activity	2/249	19/18639	0.105263157894737	7.87951807228916	0.026174248724487	0.131715574226451
GO:0016004	phospholipase activator activity	2/249	20/18639	0.1	7.4855421686747	0.0288303084019017	0.141654428683359
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	2/249	20/18639	0.1	7.4855421686747	0.0288303084019017	0.141654428683359
GO:0052745	inositol phosphate phosphatase activity	2/249	20/18639	0.1	7.4855421686747	0.0288303084019017	0.141654428683359
GO:0035591	signaling adaptor activity	5/249	129/18639	0.0387596899224806	2.90137293359484	0.0296109692057289	0.144353474877928
GO:0004252	serine-type endopeptidase activity	6/249	176/18639	0.0340909090909091	2.55188937568456	0.0310968299409	0.146087319584136
GO:0010314	phosphatidylinositol-5-phosphate binding	2/249	21/18639	0.0952380952380952	7.12908777969019	0.0315890708654555	0.146087319584136
GO:0005319	lipid transporter activity	6/249	178/18639	0.0337078651685393	2.52321646135102	0.0326004903904493	0.146087319584136
GO:0034212	protein N-acetyltransferase activity	3/249	53/18639	0.0566037735849057	4.23709934075926	0.0338261804258509	0.146087319584136
GO:0030021	extracellular matrix structural constituent conferring compression resistance	2/249	22/18639	0.0909090909090909	6.80503833515882	0.0344473417043664	0.146087319584136
GO:0032931	histone H3K56 acetyltransferase activity	2/249	22/18639	0.0909090909090909	6.80503833515882	0.0344473417043664	0.146087319584136
GO:0043992	histone H3K9 acetyltransferase activity	2/249	22/18639	0.0909090909090909	6.80503833515882	0.0344473417043664	0.146087319584136
GO:0043993	histone H3K18 acetyltransferase activity	2/249	22/18639	0.0909090909090909	6.80503833515882	0.0344473417043664	0.146087319584136
GO:0043994	histone H3K23 acetyltransferase activity	2/249	22/18639	0.0909090909090909	6.80503833515882	0.0344473417043664	0.146087319584136
GO:0043999	histone H2AK5 acetyltransferase activity	2/249	22/18639	0.0909090909090909	6.80503833515882	0.0344473417043664	0.146087319584136
GO:0044012	histone H2AK9 acetyltransferase activity	2/249	22/18639	0.0909090909090909	6.80503833515882	0.0344473417043664	0.146087319584136
GO:0044014	histone H2BK5 acetyltransferase activity	2/249	22/18639	0.0909090909090909	6.80503833515882	0.0344473417043664	0.146087319584136
GO:0044015	histone H2BK12 acetyltransferase activity	2/249	22/18639	0.0909090909090909	6.80503833515882	0.0344473417043664	0.146087319584136
GO:0044016	histone H3K4 acetyltransferase activity	2/249	22/18639	0.0909090909090909	6.80503833515882	0.0344473417043664	0.146087319584136
GO:0044017	histone H3K27 acetyltransferase activity	2/249	22/18639	0.0909090909090909	6.80503833515882	0.0344473417043664	0.146087319584136
GO:0044018	histone H3K36 acetyltransferase activity	2/249	22/18639	0.0909090909090909	6.80503833515882	0.0344473417043664	0.146087319584136
GO:0046972	histone H4K16 acetyltransferase activity	2/249	22/18639	0.0909090909090909	6.80503833515882	0.0344473417043664	0.146087319584136
GO:0140908	histone H3K122 acetyltransferase activity	2/249	22/18639	0.0909090909090909	6.80503833515882	0.0344473417043664	0.146087319584136
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	7/249	229/18639	0.0305676855895196	2.28815699479139	0.0345770267305849	0.146087319584136
GO:0003712	transcription coregulator activity	12/249	495/18639	0.0242424242424242	1.81467688937568	0.0346489155423912	0.146087319584136
GO:0017134	fibroblast growth factor binding	2/249	23/18639	0.0869565217391304	6.50916710319539	0.0374019929239059	0.154561878043161
GO:0044013	histone H2B acetyltransferase activity	2/249	23/18639	0.0869565217391304	6.50916710319539	0.0374019929239059	0.154561878043161
GO:0099186	structural constituent of postsynapse	2/249	23/18639	0.0869565217391304	6.50916710319539	0.0374019929239059	0.154561878043161
GO:0005125	cytokine activity	7/249	234/18639	0.0299145299145299	2.23926475131294	0.0381546627799033	0.155928413000993
GO:1901981	phosphatidylinositol phosphate binding	6/249	185/18639	0.0324324324324324	2.42774340605666	0.0382324474185128	0.155928413000993
GO:0016407	acetyltransferase activity	4/249	96/18639	0.0416666666666667	3.11897590361446	0.0398122160225057	0.158747019708894
GO:0031406	carboxylic acid binding	6/249	187/18639	0.0320855614973262	2.40177823593841	0.0399486074327862	0.158747019708894
GO:0043998	histone H2A acetyltransferase activity	2/249	24/18639	0.0833333333333333	6.23795180722892	0.040449961752747	0.158747019708894
GO:0050431	transforming growth factor beta binding	2/249	24/18639	0.0833333333333333	6.23795180722892	0.040449961752747	0.158747019708894
GO:0060229	lipase activator activity	2/249	24/18639	0.0833333333333333	6.23795180722892	0.040449961752747	0.158747019708894
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/249	24/18639	0.0833333333333333	6.23795180722892	0.040449961752747	0.158747019708894
GO:0043177	organic acid binding	6/249	189/18639	0.0317460317460317	2.37636259323006	0.0417129520545355	0.162680513012689
GO:0019211	phosphatase activator activity	2/249	25/18639	0.08	5.98843373493976	0.0435882494701224	0.167895479440471
GO:0042974	nuclear retinoic acid receptor binding	2/249	25/18639	0.08	5.98843373493976	0.0435882494701224	0.167895479440471
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	3/249	59/18639	0.0508474576271186	3.80620788237697	0.0443141676706974	0.169644421021566
GO:0008236	serine-type peptidase activity	6/249	194/18639	0.0309278350515464	2.31511613464166	0.0463364823028747	0.174921474476321
GO:0001664	G protein-coupled receptor binding	8/249	297/18639	0.0269360269360269	2.01630765486187	0.0466519285382488	0.174921474476321
GO:0005160	transforming growth factor beta receptor binding	2/249	26/18639	0.0769230769230769	5.758109360519	0.0468139202524768	0.174921474476321
GO:0050750	low-density lipoprotein particle receptor binding	2/249	26/18639	0.0769230769230769	5.758109360519	0.0468139202524768	0.174921474476321
GO:0015026	coreceptor activity	3/249	61/18639	0.0491803278688525	3.68141418131543	0.0481290073652937	0.178764884499662
GO:0017171	serine hydrolase activity	6/249	198/18639	0.0303030303030303	2.26834611171961	0.0502560364434077	0.18468792512028
GO:0042277	peptide binding	7/249	249/18639	0.0281124497991968	2.10436928436638	0.0503156206257172	0.18468792512028
GO:0042578	phosphoric ester hydrolase activity	9/249	363/18639	0.0247933884297521	1.8559195459524	0.0556229975055063	0.202975148792023
GO:0120013	lipid transfer activity	3/249	65/18639	0.0461538461538462	3.4548656163114	0.0562234112201482	0.203973305821933
GO:0004620	phospholipase activity	4/249	109/18639	0.036697247706422	2.74698795180723	0.0584690129201154	0.210894011919954
GO:0046982	protein heterodimerization activity	9/249	369/18639	0.024390243902439	1.82574199235968	0.0603959427258611	0.213407492255767
GO:0001965	G-protein alpha-subunit binding	2/249	30/18639	0.0666666666666667	4.99036144578313	0.0605338559763955	0.213407492255767
GO:0033612	receptor serine/threonine kinase binding	2/249	30/18639	0.0666666666666667	4.99036144578313	0.0605338559763955	0.213407492255767
GO:0098918	structural constituent of synapse	2/249	30/18639	0.0666666666666667	4.99036144578313	0.0605338559763955	0.213407492255767
GO:0097110	scaffold protein binding	3/249	70/18639	0.0428571428571429	3.20808950086059	0.0671849284218403	0.235524692894541
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	7/249	268/18639	0.0261194029850746	1.95517892465384	0.0689014287406754	0.240192690135092
GO:0043539	protein serine/threonine kinase activator activity	3/249	73/18639	0.0410958904109589	3.07625020630467	0.0741936985177686	0.256476605844247
GO:0016791	phosphatase activity	7/249	273/18639	0.0256410256410256	1.91936978683967	0.0743946565028986	0.256476605844247
GO:0001217	DNA-binding transcription repressor activity	7/249	278/18639	0.0251798561151079	1.88484874750802	0.0801395412280734	0.274764141353394
GO:0030246	carbohydrate binding	7/249	280/18639	0.025	1.87138554216867	0.0825078222110091	0.281338147867047
GO:0035091	phosphatidylinositol binding	7/249	284/18639	0.0246478873239437	1.84502799932123	0.0873645530881211	0.296279788733628
GO:0046332	SMAD binding	3/249	79/18639	0.0379746835443038	2.84261095012963	0.0891306554585418	0.300635291925028
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	4/249	128/18639	0.03125	2.33923192771084	0.0926979722020922	0.302748757287602
GO:0033192	calmodulin-dependent protein phosphatase activity	3/249	81/18639	0.037037037037037	2.77242302543507	0.0943690734614778	0.302748757287602
GO:0140791	histone H2AXS140 phosphatase activity	3/249	81/18639	0.037037037037037	2.77242302543507	0.0943690734614778	0.302748757287602
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	3/249	81/18639	0.037037037037037	2.77242302543507	0.0943690734614778	0.302748757287602
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	3/249	81/18639	0.037037037037037	2.77242302543507	0.0943690734614778	0.302748757287602
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	3/249	81/18639	0.037037037037037	2.77242302543507	0.0943690734614778	0.302748757287602
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	3/249	81/18639	0.037037037037037	2.77242302543507	0.0943690734614778	0.302748757287602
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	3/249	81/18639	0.037037037037037	2.77242302543507	0.0943690734614778	0.302748757287602
GO:1990439	MAP kinase serine/threonine phosphatase activity	3/249	81/18639	0.037037037037037	2.77242302543507	0.0943690734614778	0.302748757287602
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	2/249	39/18639	0.0512820512820513	3.83873957367933	0.0954713823605508	0.302748757287602
GO:0016298	lipase activity	4/249	130/18639	0.0307692307692308	2.3032437442076	0.0967562496670511	0.302748757287602
GO:0016798	hydrolase activity, acting on glycosyl bonds	4/249	130/18639	0.0307692307692308	2.3032437442076	0.0967562496670511	0.302748757287602
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	3/249	82/18639	0.0365853658536585	2.73861298853952	0.0970348581050006	0.302748757287602
GO:0033549	MAP kinase phosphatase activity	3/249	82/18639	0.0365853658536585	2.73861298853952	0.0970348581050006	0.302748757287602
GO:0140272	exogenous protein binding	3/249	82/18639	0.0365853658536585	2.73861298853952	0.0970348581050006	0.302748757287602
GO:0030331	nuclear estrogen receptor binding	2/249	40/18639	0.05	3.74277108433735	0.0996447909559239	0.306562485653441
GO:0001540	amyloid-beta binding	3/249	83/18639	0.036144578313253	2.7056176513282	0.0997310650443084	0.306562485653441
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	3/249	83/18639	0.036144578313253	2.7056176513282	0.0997310650443084	0.306562485653441
GO:0005179	hormone activity	4/249	132/18639	0.0303030303030303	2.26834611171961	0.100896695452634	0.30862518609041
GO:0017018	myosin phosphatase activity	3/249	84/18639	0.0357142857142857	2.67340791738382	0.102457218357918	0.3101141610763
GO:0141003	histone H2AX kinase activity	8/249	354/18639	0.0225988700564972	1.6916479477231	0.103204278400894	0.3101141610763
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	2/249	41/18639	0.0487804878048781	3.65148398471937	0.103868364847671	0.3101141610763
GO:0015175	neutral L-amino acid transmembrane transporter activity	2/249	41/18639	0.0487804878048781	3.65148398471937	0.103868364847671	0.3101141610763
GO:0042169	SH2 domain binding	2/249	41/18639	0.0487804878048781	3.65148398471937	0.103868364847671	0.3101141610763
GO:0140996	histone H3 kinase activity	8/249	357/18639	0.0224089635854342	1.67743241875063	0.106932899295533	0.31774347219244
GO:0008307	structural constituent of muscle	2/249	42/18639	0.0476190476190476	3.56454388984509	0.108140032478579	0.319807489415325
GO:0044325	transmembrane transporter binding	4/249	136/18639	0.0294117647058824	2.20163004961021	0.109418557802586	0.320550141168138
GO:0140789	histone phosphatase activity	4/249	136/18639	0.0294117647058824	2.20163004961021	0.109418557802586	0.320550141168138
GO:0035173	histone kinase activity	8/249	360/18639	0.0222222222222222	1.66345381526104	0.110735313320809	0.322891754729836
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	3/249	89/18639	0.0337078651685393	2.52321646135102	0.116520298220068	0.3300069189823
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	3/249	89/18639	0.0337078651685393	2.52321646135102	0.116520298220068	0.3300069189823
GO:0140793	histone H2AXY142 phosphatase activity	3/249	90/18639	0.0333333333333333	2.49518072289157	0.119415963027255	0.3300069189823
GO:0042605	peptide antigen binding	2/249	45/18639	0.0444444444444444	3.32690763052209	0.121223567020694	0.3300069189823
GO:0030291	protein serine/threonine kinase inhibitor activity	2/249	46/18639	0.0434782608695652	3.25458355159769	0.125667801195774	0.3300069189823
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/249	10/18639	0.1	7.4855421686747	0.125868023586198	0.3300069189823
GO:0005131	growth hormone receptor binding	1/249	10/18639	0.1	7.4855421686747	0.125868023586198	0.3300069189823
GO:0005381	iron ion transmembrane transporter activity	1/249	10/18639	0.1	7.4855421686747	0.125868023586198	0.3300069189823
GO:0005528	FK506 binding	1/249	10/18639	0.1	7.4855421686747	0.125868023586198	0.3300069189823
GO:0015187	glycine transmembrane transporter activity	1/249	10/18639	0.1	7.4855421686747	0.125868023586198	0.3300069189823
GO:0015203	polyamine transmembrane transporter activity	1/249	10/18639	0.1	7.4855421686747	0.125868023586198	0.3300069189823
GO:0015643	toxic substance binding	1/249	10/18639	0.1	7.4855421686747	0.125868023586198	0.3300069189823
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/249	10/18639	0.1	7.4855421686747	0.125868023586198	0.3300069189823
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/249	10/18639	0.1	7.4855421686747	0.125868023586198	0.3300069189823
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	1/249	10/18639	0.1	7.4855421686747	0.125868023586198	0.3300069189823
GO:0030957	Tat protein binding	1/249	10/18639	0.1	7.4855421686747	0.125868023586198	0.3300069189823
GO:0035256	G protein-coupled glutamate receptor binding	1/249	10/18639	0.1	7.4855421686747	0.125868023586198	0.3300069189823
GO:0035374	chondroitin sulfate binding	1/249	10/18639	0.1	7.4855421686747	0.125868023586198	0.3300069189823
GO:0042975	peroxisome proliferator activated receptor binding	1/249	10/18639	0.1	7.4855421686747	0.125868023586198	0.3300069189823
GO:0043121	neurotrophin binding	1/249	10/18639	0.1	7.4855421686747	0.125868023586198	0.3300069189823
GO:0043295	glutathione binding	1/249	10/18639	0.1	7.4855421686747	0.125868023586198	0.3300069189823
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/249	10/18639	0.1	7.4855421686747	0.125868023586198	0.3300069189823
GO:1905394	retromer complex binding	1/249	10/18639	0.1	7.4855421686747	0.125868023586198	0.3300069189823
GO:1990757	ubiquitin ligase activator activity	1/249	10/18639	0.1	7.4855421686747	0.125868023586198	0.3300069189823
GO:0005504	fatty acid binding	2/249	47/18639	0.0425531914893617	3.18533709305306	0.130150444398528	0.335282746883416
GO:0140359	ABC-type transporter activity	2/249	47/18639	0.0425531914893617	3.18533709305306	0.130150444398528	0.335282746883416
GO:0032266	phosphatidylinositol-3-phosphate binding	2/249	48/18639	0.0416666666666667	3.11897590361446	0.13466968854405	0.335282746883416
GO:0004016	adenylate cyclase activity	1/249	11/18639	0.0909090909090909	6.80503833515882	0.137551896157299	0.335282746883416
GO:0005114	type II transforming growth factor beta receptor binding	1/249	11/18639	0.0909090909090909	6.80503833515882	0.137551896157299	0.335282746883416
GO:0005536	D-glucose binding	1/249	11/18639	0.0909090909090909	6.80503833515882	0.137551896157299	0.335282746883416
GO:0008199	ferric iron binding	1/249	11/18639	0.0909090909090909	6.80503833515882	0.137551896157299	0.335282746883416
GO:0010854	adenylate cyclase regulator activity	1/249	11/18639	0.0909090909090909	6.80503833515882	0.137551896157299	0.335282746883416
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/249	11/18639	0.0909090909090909	6.80503833515882	0.137551896157299	0.335282746883416
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/249	11/18639	0.0909090909090909	6.80503833515882	0.137551896157299	0.335282746883416
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	1/249	11/18639	0.0909090909090909	6.80503833515882	0.137551896157299	0.335282746883416
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/249	11/18639	0.0909090909090909	6.80503833515882	0.137551896157299	0.335282746883416
GO:0034713	type I transforming growth factor beta receptor binding	1/249	11/18639	0.0909090909090909	6.80503833515882	0.137551896157299	0.335282746883416
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/249	11/18639	0.0909090909090909	6.80503833515882	0.137551896157299	0.335282746883416
GO:0050786	RAGE receptor binding	1/249	11/18639	0.0909090909090909	6.80503833515882	0.137551896157299	0.335282746883416
GO:0070697	activin receptor binding	1/249	11/18639	0.0909090909090909	6.80503833515882	0.137551896157299	0.335282746883416
GO:0097493	structural molecule activity conferring elasticity	1/249	11/18639	0.0909090909090909	6.80503833515882	0.137551896157299	0.335282746883416
GO:1900750	oligopeptide binding	1/249	11/18639	0.0909090909090909	6.80503833515882	0.137551896157299	0.335282746883416
GO:0004725	protein tyrosine phosphatase activity	3/249	98/18639	0.0306122448979592	2.2914925006147	0.143494815431581	0.344540948089375
GO:0016597	amino acid binding	2/249	51/18639	0.0392156862745098	2.93550673281361	0.148429557661231	0.344540948089375
GO:0051015	actin filament binding	5/249	209/18639	0.0239234449760766	1.7907995618839	0.148747973631557	0.344540948089375
GO:0004000	adenosine deaminase activity	1/249	12/18639	0.0833333333333333	6.23795180722892	0.149080217923287	0.344540948089375
GO:0004300	enoyl-CoA hydratase activity	1/249	12/18639	0.0833333333333333	6.23795180722892	0.149080217923287	0.344540948089375
GO:0005165	neurotrophin receptor binding	1/249	12/18639	0.0833333333333333	6.23795180722892	0.149080217923287	0.344540948089375
GO:0008504	monoamine transmembrane transporter activity	1/249	12/18639	0.0833333333333333	6.23795180722892	0.149080217923287	0.344540948089375
GO:0008603	cAMP-dependent protein kinase regulator activity	1/249	12/18639	0.0833333333333333	6.23795180722892	0.149080217923287	0.344540948089375
GO:0015269	calcium-activated potassium channel activity	1/249	12/18639	0.0833333333333333	6.23795180722892	0.149080217923287	0.344540948089375
GO:0017166	vinculin binding	1/249	12/18639	0.0833333333333333	6.23795180722892	0.149080217923287	0.344540948089375
GO:0035259	nuclear glucocorticoid receptor binding	1/249	12/18639	0.0833333333333333	6.23795180722892	0.149080217923287	0.344540948089375
GO:0045295	gamma-catenin binding	1/249	12/18639	0.0833333333333333	6.23795180722892	0.149080217923287	0.344540948089375
GO:1990247	N6-methyladenosine-containing RNA reader activity	1/249	12/18639	0.0833333333333333	6.23795180722892	0.149080217923287	0.344540948089375
GO:1990459	transferrin receptor binding	1/249	12/18639	0.0833333333333333	6.23795180722892	0.149080217923287	0.344540948089375
GO:0005246	calcium channel regulator activity	2/249	53/18639	0.0377358490566038	2.82473289383951	0.157754474649171	0.356312997009156
GO:0004722	protein serine/threonine phosphatase activity	3/249	103/18639	0.029126213592233	2.18025500058486	0.159293275132976	0.356312997009156
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/249	13/18639	0.0769230769230769	5.758109360519	0.160455051537777	0.356312997009156
GO:0005172	vascular endothelial growth factor receptor binding	1/249	13/18639	0.0769230769230769	5.758109360519	0.160455051537777	0.356312997009156
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/249	13/18639	0.0769230769230769	5.758109360519	0.160455051537777	0.356312997009156
GO:0019855	calcium channel inhibitor activity	1/249	13/18639	0.0769230769230769	5.758109360519	0.160455051537777	0.356312997009156
GO:0035325	Toll-like receptor binding	1/249	13/18639	0.0769230769230769	5.758109360519	0.160455051537777	0.356312997009156
GO:0070123	transforming growth factor beta receptor activity, type III	1/249	13/18639	0.0769230769230769	5.758109360519	0.160455051537777	0.356312997009156
GO:0070700	BMP receptor binding	1/249	13/18639	0.0769230769230769	5.758109360519	0.160455051537777	0.356312997009156
GO:0071837	HMG box domain binding	1/249	13/18639	0.0769230769230769	5.758109360519	0.160455051537777	0.356312997009156
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/249	13/18639	0.0769230769230769	5.758109360519	0.160455051537777	0.356312997009156
GO:0008013	beta-catenin binding	3/249	106/18639	0.0283018867924528	2.11854967037963	0.169017143207176	0.370682843685868
GO:0008559	ABC-type xenobiotic transporter activity	1/249	14/18639	0.0714285714285714	5.34681583476764	0.171678432412205	0.370682843685868
GO:0016530	metallochaperone activity	1/249	14/18639	0.0714285714285714	5.34681583476764	0.171678432412205	0.370682843685868
GO:0034236	protein kinase A catalytic subunit binding	1/249	14/18639	0.0714285714285714	5.34681583476764	0.171678432412205	0.370682843685868
GO:0042043	neurexin family protein binding	1/249	14/18639	0.0714285714285714	5.34681583476764	0.171678432412205	0.370682843685868
GO:0043176	amine binding	1/249	14/18639	0.0714285714285714	5.34681583476764	0.171678432412205	0.370682843685868
GO:1901474	azole transmembrane transporter activity	1/249	14/18639	0.0714285714285714	5.34681583476764	0.171678432412205	0.370682843685868
GO:1901612	cardiolipin binding	1/249	14/18639	0.0714285714285714	5.34681583476764	0.171678432412205	0.370682843685868
GO:0004601	peroxidase activity	2/249	57/18639	0.0350877192982456	2.62650602409639	0.176711341377585	0.380234058688321
GO:0031267	small GTPase binding	6/249	283/18639	0.0212014134275618	1.5870407424752	0.178986171308311	0.383805398269368
GO:0005523	tropomyosin binding	1/249	15/18639	0.0666666666666667	4.99036144578313	0.182752369074184	0.383964573408387
GO:0008242	omega peptidase activity	1/249	15/18639	0.0666666666666667	4.99036144578313	0.182752369074184	0.383964573408387
GO:0015929	hexosaminidase activity	1/249	15/18639	0.0666666666666667	4.99036144578313	0.182752369074184	0.383964573408387
GO:0033130	acetylcholine receptor binding	1/249	15/18639	0.0666666666666667	4.99036144578313	0.182752369074184	0.383964573408387
GO:0050780	dopamine receptor binding	1/249	15/18639	0.0666666666666667	4.99036144578313	0.182752369074184	0.383964573408387
GO:0120283	protein serine/threonine kinase binding	1/249	15/18639	0.0666666666666667	4.99036144578313	0.182752369074184	0.383964573408387
GO:1902936	phosphatidylinositol bisphosphate binding	3/249	111/18639	0.027027027027027	2.02311950504722	0.185588937627504	0.388615762011955
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	7/249	349/18639	0.0200573065902579	1.50139814271412	0.187339119381254	0.390968596969574
GO:0005200	structural constituent of cytoskeleton	3/249	112/18639	0.0267857142857143	2.00505593803787	0.188953725197355	0.393023748410499
GO:0005024	transforming growth factor beta receptor activity	1/249	16/18639	0.0625	4.67846385542169	0.193678843521162	0.396247863466247
GO:0005521	lamin binding	1/249	16/18639	0.0625	4.67846385542169	0.193678843521162	0.396247863466247
GO:0022841	potassium ion leak channel activity	1/249	16/18639	0.0625	4.67846385542169	0.193678843521162	0.396247863466247
GO:0034450	ubiquitin-ubiquitin ligase activity	1/249	16/18639	0.0625	4.67846385542169	0.193678843521162	0.396247863466247
GO:0097027	ubiquitin-protein transferase activator activity	1/249	16/18639	0.0625	4.67846385542169	0.193678843521162	0.396247863466247
GO:0001221	transcription coregulator binding	3/249	115/18639	0.0260869565217391	1.95275013095862	0.199140317372859	0.401706851324493
GO:0017124	SH3 domain binding	3/249	115/18639	0.0260869565217391	1.95275013095862	0.199140317372859	0.401706851324493
GO:0015179	L-amino acid transmembrane transporter activity	2/249	62/18639	0.032258064516129	2.41469102215313	0.200862896312212	0.401706851324493
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	1/249	17/18639	0.0588235294117647	4.40326009922041	0.204459811569448	0.401706851324493
GO:0008429	phosphatidylethanolamine binding	1/249	17/18639	0.0588235294117647	4.40326009922041	0.204459811569448	0.401706851324493
GO:0030169	low-density lipoprotein particle binding	1/249	17/18639	0.0588235294117647	4.40326009922041	0.204459811569448	0.401706851324493
GO:0036041	long-chain fatty acid binding	1/249	17/18639	0.0588235294117647	4.40326009922041	0.204459811569448	0.401706851324493
GO:0038191	neuropilin binding	1/249	17/18639	0.0588235294117647	4.40326009922041	0.204459811569448	0.401706851324493
GO:0045125	bioactive lipid receptor activity	1/249	17/18639	0.0588235294117647	4.40326009922041	0.204459811569448	0.401706851324493
GO:0045236	CXCR chemokine receptor binding	1/249	17/18639	0.0588235294117647	4.40326009922041	0.204459811569448	0.401706851324493
GO:0048038	quinone binding	1/249	17/18639	0.0588235294117647	4.40326009922041	0.204459811569448	0.401706851324493
GO:1990226	histone methyltransferase binding	1/249	17/18639	0.0588235294117647	4.40326009922041	0.204459811569448	0.401706851324493
GO:0005507	copper ion binding	2/249	63/18639	0.0317460317460317	2.37636259323006	0.205740381439411	0.401706851324493
GO:0019208	phosphatase regulator activity	3/249	117/18639	0.0256410256410256	1.91936978683967	0.20600351349974	0.401706851324493
GO:1990782	protein tyrosine kinase binding	3/249	117/18639	0.0256410256410256	1.91936978683967	0.20600351349974	0.401706851324493
GO:0004721	phosphoprotein phosphatase activity	4/249	175/18639	0.0228571428571429	1.71098106712565	0.206806773629373	0.402016905746818
GO:0000400	four-way junction DNA binding	1/249	18/18639	0.0555555555555556	4.15863453815261	0.215097203198662	0.405500467661526
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/249	18/18639	0.0555555555555556	4.15863453815261	0.215097203198662	0.405500467661526
GO:0015172	acidic amino acid transmembrane transporter activity	1/249	18/18639	0.0555555555555556	4.15863453815261	0.215097203198662	0.405500467661526
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	1/249	18/18639	0.0555555555555556	4.15863453815261	0.215097203198662	0.405500467661526
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/249	18/18639	0.0555555555555556	4.15863453815261	0.215097203198662	0.405500467661526
GO:0050811	GABA receptor binding	1/249	18/18639	0.0555555555555556	4.15863453815261	0.215097203198662	0.405500467661526
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	1/249	18/18639	0.0555555555555556	4.15863453815261	0.215097203198662	0.405500467661526
GO:0070064	proline-rich region binding	1/249	18/18639	0.0555555555555556	4.15863453815261	0.215097203198662	0.405500467661526
GO:1901611	phosphatidylglycerol binding	1/249	18/18639	0.0555555555555556	4.15863453815261	0.215097203198662	0.405500467661526
GO:1990381	ubiquitin-specific protease binding	1/249	18/18639	0.0555555555555556	4.15863453815261	0.215097203198662	0.405500467661526
GO:0003756	protein disulfide isomerase activity	1/249	19/18639	0.0526315789473684	3.93975903614458	0.225592922891671	0.415250689924492
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/249	19/18639	0.0526315789473684	3.93975903614458	0.225592922891671	0.415250689924492
GO:0008301	DNA binding, bending	1/249	19/18639	0.0526315789473684	3.93975903614458	0.225592922891671	0.415250689924492
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	1/249	19/18639	0.0526315789473684	3.93975903614458	0.225592922891671	0.415250689924492
GO:0022840	leak channel activity	1/249	19/18639	0.0526315789473684	3.93975903614458	0.225592922891671	0.415250689924492
GO:0022842	narrow pore channel activity	1/249	19/18639	0.0526315789473684	3.93975903614458	0.225592922891671	0.415250689924492
GO:0070003	threonine-type peptidase activity	1/249	19/18639	0.0526315789473684	3.93975903614458	0.225592922891671	0.415250689924492
GO:0097001	ceramide binding	1/249	19/18639	0.0526315789473684	3.93975903614458	0.225592922891671	0.415250689924492
GO:1990841	promoter-specific chromatin binding	2/249	68/18639	0.0294117647058824	2.20163004961021	0.23029566680446	0.422660282605833
GO:0005326	neurotransmitter transmembrane transporter activity	1/249	20/18639	0.05	3.74277108433735	0.23594884997008	0.429248053589884
GO:0010851	cyclase regulator activity	1/249	20/18639	0.05	3.74277108433735	0.23594884997008	0.429248053589884
GO:0031418	L-ascorbic acid binding	1/249	20/18639	0.05	3.74277108433735	0.23594884997008	0.429248053589884
GO:0001846	opsonin binding	1/249	21/18639	0.0476190476190476	3.56454388984509	0.246166838925311	0.440143355488189
GO:0009975	cyclase activity	1/249	21/18639	0.0476190476190476	3.56454388984509	0.246166838925311	0.440143355488189
GO:0036122	BMP binding	1/249	21/18639	0.0476190476190476	3.56454388984509	0.246166838925311	0.440143355488189
GO:0051428	peptide hormone receptor binding	1/249	21/18639	0.0476190476190476	3.56454388984509	0.246166838925311	0.440143355488189
GO:0072542	protein phosphatase activator activity	1/249	21/18639	0.0476190476190476	3.56454388984509	0.246166838925311	0.440143355488189
GO:0051020	GTPase binding	6/249	315/18639	0.019047619047619	1.42581755593804	0.246169921579132	0.440143355488189
GO:0031072	heat shock protein binding	3/249	131/18639	0.0229007633587786	1.71424629816978	0.255337500822965	0.454259094094041
GO:0031683	G-protein beta/gamma-subunit complex binding	1/249	22/18639	0.0454545454545455	3.40251916757941	0.256248719745356	0.454259094094041
GO:0140517	protein-RNA adaptor activity	1/249	22/18639	0.0454545454545455	3.40251916757941	0.256248719745356	0.454259094094041
GO:0048029	monosaccharide binding	2/249	74/18639	0.027027027027027	2.02311950504722	0.259984483323576	0.459575970520996
GO:0003725	double-stranded RNA binding	2/249	75/18639	0.0266666666666667	1.99614457831325	0.264941883837283	0.46140691694455
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	1/249	23/18639	0.0434782608695652	3.25458355159769	0.26619629823724	0.46140691694455
GO:0004602	glutathione peroxidase activity	1/249	23/18639	0.0434782608695652	3.25458355159769	0.26619629823724	0.46140691694455
GO:0005283	amino acid:sodium symporter activity	1/249	23/18639	0.0434782608695652	3.25458355159769	0.26619629823724	0.46140691694455
GO:0016849	phosphorus-oxygen lyase activity	1/249	23/18639	0.0434782608695652	3.25458355159769	0.26619629823724	0.46140691694455
GO:0043274	phospholipase binding	1/249	23/18639	0.0434782608695652	3.25458355159769	0.26619629823724	0.46140691694455
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	1/249	23/18639	0.0434782608695652	3.25458355159769	0.26619629823724	0.46140691694455
GO:0017022	myosin binding	2/249	76/18639	0.0263157894736842	1.96987951807229	0.269899425090272	0.466529754172659
GO:0004622	lysophospholipase activity	1/249	24/18639	0.0416666666666667	3.11897590361446	0.276011356345262	0.471865990025872
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/249	24/18639	0.0416666666666667	3.11897590361446	0.276011356345262	0.471865990025872
GO:0030552	cAMP binding	1/249	24/18639	0.0416666666666667	3.11897590361446	0.276011356345262	0.471865990025872
GO:0048027	mRNA 5'-UTR binding	1/249	24/18639	0.0416666666666667	3.11897590361446	0.276011356345262	0.471865990025872
GO:0016922	nuclear receptor binding	3/249	137/18639	0.0218978102189781	1.63916981795796	0.276981013303613	0.472229924320915
GO:0033293	monocarboxylic acid binding	2/249	79/18639	0.0253164556962025	1.89507396675309	0.284764160355437	0.477296826876226
GO:0001848	complement binding	1/249	25/18639	0.04	2.99421686746988	0.285695652465059	0.477296826876226
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/249	25/18639	0.04	2.99421686746988	0.285695652465059	0.477296826876226
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/249	25/18639	0.04	2.99421686746988	0.285695652465059	0.477296826876226
GO:0019706	protein-cysteine S-palmitoyltransferase activity	1/249	25/18639	0.04	2.99421686746988	0.285695652465059	0.477296826876226
GO:0019707	protein-cysteine S-acyltransferase activity	1/249	25/18639	0.04	2.99421686746988	0.285695652465059	0.477296826876226
GO:0048306	calcium-dependent protein binding	2/249	80/18639	0.025	1.87138554216867	0.289713646948022	0.477296826876226
GO:0003714	transcription corepressor activity	4/249	204/18639	0.0196078431372549	1.4677533664068	0.290713633664386	0.477296826876226
GO:0008514	organic anion transmembrane transporter activity	5/249	269/18639	0.0185873605947955	1.39136471536704	0.291217774959433	0.477296826876226
GO:0001618	virus receptor activity	2/249	81/18639	0.0246913580246914	1.84828201695672	0.294659079188187	0.477296826876226
GO:0030971	receptor tyrosine kinase binding	2/249	81/18639	0.0246913580246914	1.84828201695672	0.294659079188187	0.477296826876226
GO:0020037	heme binding	3/249	142/18639	0.0211267605633803	1.58145257084677	0.295152778852588	0.477296826876226
GO:0005227	calcium-activated cation channel activity	1/249	26/18639	0.0384615384615385	2.8790546802595	0.295250921753563	0.477296826876226
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	1/249	26/18639	0.0384615384615385	2.8790546802595	0.295250921753563	0.477296826876226
GO:0008143	poly(A) binding	1/249	26/18639	0.0384615384615385	2.8790546802595	0.295250921753563	0.477296826876226
GO:0008198	ferrous iron binding	1/249	26/18639	0.0384615384615385	2.8790546802595	0.295250921753563	0.477296826876226
GO:0019865	immunoglobulin binding	1/249	26/18639	0.0384615384615385	2.8790546802595	0.295250921753563	0.477296826876226
GO:0030247	polysaccharide binding	1/249	26/18639	0.0384615384615385	2.8790546802595	0.295250921753563	0.477296826876226
GO:0052742	phosphatidylinositol kinase activity	1/249	26/18639	0.0384615384615385	2.8790546802595	0.295250921753563	0.477296826876226
GO:0070006	metalloaminopeptidase activity	1/249	26/18639	0.0384615384615385	2.8790546802595	0.295250921753563	0.477296826876226
GO:0005516	calmodulin binding	4/249	207/18639	0.0193236714975845	1.44648157848786	0.299691933190605	0.482537103795343
GO:0019903	protein phosphatase binding	3/249	144/18639	0.0208333333333333	1.55948795180723	0.302444396286354	0.482537103795343
GO:0004364	glutathione transferase activity	1/249	27/18639	0.037037037037037	2.77242302543507	0.30467887643488	0.482537103795343
GO:0005385	zinc ion transmembrane transporter activity	1/249	27/18639	0.037037037037037	2.77242302543507	0.30467887643488	0.482537103795343
GO:0008266	poly(U) RNA binding	1/249	27/18639	0.037037037037037	2.77242302543507	0.30467887643488	0.482537103795343
GO:0015252	proton channel activity	1/249	27/18639	0.037037037037037	2.77242302543507	0.30467887643488	0.482537103795343
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	1/249	27/18639	0.037037037037037	2.77242302543507	0.30467887643488	0.482537103795343
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	1/249	27/18639	0.037037037037037	2.77242302543507	0.30467887643488	0.482537103795343
GO:0004860	protein kinase inhibitor activity	2/249	84/18639	0.0238095238095238	1.78227194492255	0.309463431727404	0.486164448158208
GO:0005242	inward rectifier potassium channel activity	1/249	28/18639	0.0357142857142857	2.67340791738382	0.313981206102176	0.486164448158208
GO:0045499	chemorepellent activity	1/249	28/18639	0.0357142857142857	2.67340791738382	0.313981206102176	0.486164448158208
GO:0046625	sphingolipid binding	1/249	28/18639	0.0357142857142857	2.67340791738382	0.313981206102176	0.486164448158208
GO:0046966	nuclear thyroid hormone receptor binding	1/249	28/18639	0.0357142857142857	2.67340791738382	0.313981206102176	0.486164448158208
GO:0050698	proteoglycan sulfotransferase activity	1/249	28/18639	0.0357142857142857	2.67340791738382	0.313981206102176	0.486164448158208
GO:0051019	mitogen-activated protein kinase binding	1/249	28/18639	0.0357142857142857	2.67340791738382	0.313981206102176	0.486164448158208
GO:0051959	dynein light intermediate chain binding	1/249	28/18639	0.0357142857142857	2.67340791738382	0.313981206102176	0.486164448158208
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	1/249	28/18639	0.0357142857142857	2.67340791738382	0.313981206102176	0.486164448158208
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	2/249	86/18639	0.0232558139534884	1.74082376015691	0.31929912536873	0.491957170938488
GO:0050660	flavin adenine dinucleotide binding	2/249	86/18639	0.0232558139534884	1.74082376015691	0.31929912536873	0.491957170938488
GO:0004629	phospholipase C activity	1/249	29/18639	0.0344827586206897	2.58122143747403	0.323159578015591	0.494244060494433
GO:0005416	amino acid:monoatomic cation symporter activity	1/249	29/18639	0.0344827586206897	2.58122143747403	0.323159578015591	0.494244060494433
GO:0016417	S-acyltransferase activity	1/249	29/18639	0.0344827586206897	2.58122143747403	0.323159578015591	0.494244060494433
GO:0004197	cysteine-type endopeptidase activity	2/249	88/18639	0.0227272727272727	1.7012595837897	0.329101322151229	0.499524235506654
GO:0046906	tetrapyrrole binding	3/249	152/18639	0.0197368421052632	1.47740963855422	0.331669939976798	0.499524235506654
GO:0008187	poly-pyrimidine tract binding	1/249	30/18639	0.0333333333333333	2.49518072289157	0.332215637396253	0.499524235506654
GO:0022839	monoatomic ion-gated channel activity	1/249	30/18639	0.0333333333333333	2.49518072289157	0.332215637396253	0.499524235506654
GO:0031210	phosphatidylcholine binding	1/249	30/18639	0.0333333333333333	2.49518072289157	0.332215637396253	0.499524235506654
GO:0048019	receptor antagonist activity	1/249	30/18639	0.0333333333333333	2.49518072289157	0.332215637396253	0.499524235506654
GO:0051721	protein phosphatase 2A binding	1/249	30/18639	0.0333333333333333	2.49518072289157	0.332215637396253	0.499524235506654
GO:0019210	kinase inhibitor activity	2/249	90/18639	0.0222222222222222	1.66345381526104	0.338864884951018	0.506852925750137
GO:0005164	tumor necrosis factor receptor binding	1/249	31/18639	0.032258064516129	2.41469102215313	0.341151007716438	0.506852925750137
GO:0017147	Wnt-protein binding	1/249	31/18639	0.032258064516129	2.41469102215313	0.341151007716438	0.506852925750137
GO:0070273	phosphatidylinositol-4-phosphate binding	1/249	31/18639	0.032258064516129	2.41469102215313	0.341151007716438	0.506852925750137
GO:0072349	modified amino acid transmembrane transporter activity	1/249	31/18639	0.032258064516129	2.41469102215313	0.341151007716438	0.506852925750137
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	2/249	91/18639	0.021978021978022	1.64517410300543	0.343730653987961	0.509472513274318
GO:0015106	bicarbonate transmembrane transporter activity	1/249	32/18639	0.03125	2.33923192771084	0.349967290985925	0.515046201828342
GO:0042910	xenobiotic transmembrane transporter activity	1/249	32/18639	0.03125	2.33923192771084	0.349967290985925	0.515046201828342
GO:0070717	poly-purine tract binding	1/249	32/18639	0.03125	2.33923192771084	0.349967290985925	0.515046201828342
GO:0051213	dioxygenase activity	2/249	93/18639	0.021505376344086	1.60979401476875	0.353427273677875	0.518914397117633
GO:0019239	deaminase activity	1/249	33/18639	0.0303030303030303	2.26834611171961	0.35866606803459	0.521696098959403
GO:0019956	chemokine binding	1/249	33/18639	0.0303030303030303	2.26834611171961	0.35866606803459	0.521696098959403
GO:0071889	14-3-3 protein binding	1/249	33/18639	0.0303030303030303	2.26834611171961	0.35866606803459	0.521696098959403
GO:0140416	transcription regulator inhibitor activity	1/249	33/18639	0.0303030303030303	2.26834611171961	0.35866606803459	0.521696098959403
GO:0008376	acetylgalactosaminyltransferase activity	1/249	34/18639	0.0294117647058824	2.20163004961021	0.367248898791302	0.525603928545349
GO:0015035	protein-disulfide reductase activity	1/249	34/18639	0.0294117647058824	2.20163004961021	0.367248898791302	0.525603928545349
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	1/249	34/18639	0.0294117647058824	2.20163004961021	0.367248898791302	0.525603928545349
GO:0019825	oxygen binding	1/249	34/18639	0.0294117647058824	2.20163004961021	0.367248898791302	0.525603928545349
GO:0051427	hormone receptor binding	1/249	34/18639	0.0294117647058824	2.20163004961021	0.367248898791302	0.525603928545349
GO:0052866	phosphatidylinositol phosphate phosphatase activity	1/249	34/18639	0.0294117647058824	2.20163004961021	0.367248898791302	0.525603928545349
GO:0090482	vitamin transmembrane transporter activity	1/249	34/18639	0.0294117647058824	2.20163004961021	0.367248898791302	0.525603928545349
GO:0000287	magnesium ion binding	4/249	230/18639	0.0173913043478261	1.30183342063908	0.369213264832077	0.527206126442141
GO:0005343	organic acid:sodium symporter activity	1/249	35/18639	0.0285714285714286	2.13872633390706	0.375717322559158	0.534806478423551
GO:0005249	voltage-gated potassium channel activity	2/249	98/18639	0.0204081632653061	1.52766166707647	0.377440098964341	0.534806478423551
GO:0042626	ATPase-coupled transmembrane transporter activity	2/249	98/18639	0.0204081632653061	1.52766166707647	0.377440098964341	0.534806478423551
GO:0031625	ubiquitin protein ligase binding	5/249	302/18639	0.0165562913907285	1.23932817362164	0.377964193885875	0.534806478423551
GO:0016409	palmitoyltransferase activity	1/249	36/18639	0.0277777777777778	2.07931726907631	0.384072858287108	0.537357541639361
GO:0055106	ubiquitin-protein transferase regulator activity	1/249	36/18639	0.0277777777777778	2.07931726907631	0.384072858287108	0.537357541639361
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	1/249	36/18639	0.0277777777777778	2.07931726907631	0.384072858287108	0.537357541639361
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	1/249	36/18639	0.0277777777777778	2.07931726907631	0.384072858287108	0.537357541639361
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	1/249	36/18639	0.0277777777777778	2.07931726907631	0.384072858287108	0.537357541639361
GO:0030280	structural constituent of skin epidermis	1/249	37/18639	0.027027027027027	2.02311950504722	0.392317004838014	0.546441542452947
GO:0030551	cyclic nucleotide binding	1/249	37/18639	0.027027027027027	2.02311950504722	0.392317004838014	0.546441542452947
GO:0008238	exopeptidase activity	2/249	102/18639	0.0196078431372549	1.4677533664068	0.396382856991033	0.549650895027566
GO:0015171	amino acid transmembrane transporter activity	2/249	102/18639	0.0196078431372549	1.4677533664068	0.396382856991033	0.549650895027566
GO:0000146	microfilament motor activity	1/249	38/18639	0.0263157894736842	1.96987951807229	0.400451241253202	0.552835341907076
GO:0005109	frizzled binding	1/249	38/18639	0.0263157894736842	1.96987951807229	0.400451241253202	0.552835341907076
GO:0000217	DNA secondary structure binding	1/249	39/18639	0.0256410256410256	1.91936978683967	0.408477027013535	0.561430979860013
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	1/249	39/18639	0.0256410256410256	1.91936978683967	0.408477027013535	0.561430979860013
GO:0022804	active transmembrane transporter activity	7/249	457/18639	0.0153172866520788	1.14658195143814	0.410862542336201	0.563468629489648
GO:0004177	aminopeptidase activity	1/249	40/18639	0.025	1.87138554216867	0.416395802297064	0.566080567828688
GO:0015036	disulfide oxidoreductase activity	1/249	40/18639	0.025	1.87138554216867	0.416395802297064	0.566080567828688
GO:0050997	quaternary ammonium group binding	1/249	40/18639	0.025	1.87138554216867	0.416395802297064	0.566080567828688
GO:0071949	FAD binding	1/249	40/18639	0.025	1.87138554216867	0.416395802297064	0.566080567828688
GO:0019888	protein phosphatase regulator activity	2/249	107/18639	0.0186915887850467	1.39916676049994	0.419681875245924	0.569307587290123
GO:0001727	lipid kinase activity	1/249	41/18639	0.024390243902439	1.82574199235968	0.424208988233298	0.572957594496922
GO:0140318	protein transporter activity	1/249	41/18639	0.024390243902439	1.82574199235968	0.424208988233298	0.572957594496922
GO:0044389	ubiquitin-like protein ligase binding	5/249	322/18639	0.015527950310559	1.16235126842775	0.430753072810908	0.577123820094618
GO:0016859	cis-trans isomerase activity	1/249	42/18639	0.0238095238095238	1.78227194492255	0.431917987154145	0.577123820094618
GO:0019894	kinesin binding	1/249	42/18639	0.0238095238095238	1.78227194492255	0.431917987154145	0.577123820094618
GO:0042056	chemoattractant activity	1/249	42/18639	0.0238095238095238	1.78227194492255	0.431917987154145	0.577123820094618
GO:0048487	beta-tubulin binding	1/249	42/18639	0.0238095238095238	1.78227194492255	0.431917987154145	0.577123820094618
GO:0008200	ion channel inhibitor activity	1/249	43/18639	0.0232558139534884	1.74082376015691	0.439524182841547	0.584782708087688
GO:0008375	acetylglucosaminyltransferase activity	1/249	43/18639	0.0232558139534884	1.74082376015691	0.439524182841547	0.584782708087688
GO:0001223	transcription coactivator binding	1/249	44/18639	0.0227272727272727	1.7012595837897	0.447028940771879	0.59098741322384
GO:0016248	channel inhibitor activity	1/249	44/18639	0.0227272727272727	1.7012595837897	0.447028940771879	0.59098741322384
GO:0030547	signaling receptor inhibitor activity	1/249	44/18639	0.0227272727272727	1.7012595837897	0.447028940771879	0.59098741322384
GO:0004715	non-membrane spanning protein tyrosine kinase activity	1/249	45/18639	0.0222222222222222	1.66345381526104	0.454433608357134	0.595728091627839
GO:0008009	chemokine activity	1/249	45/18639	0.0222222222222222	1.66345381526104	0.454433608357134	0.595728091627839
GO:0046915	transition metal ion transmembrane transporter activity	1/249	45/18639	0.0222222222222222	1.66345381526104	0.454433608357134	0.595728091627839
GO:0141110	transporter inhibitor activity	1/249	45/18639	0.0222222222222222	1.66345381526104	0.454433608357134	0.595728091627839
GO:0015294	solute:monoatomic cation symporter activity	2/249	116/18639	0.0172413793103448	1.29061071873702	0.460424594493594	0.601371258477549
GO:0046943	carboxylic acid transmembrane transporter activity	3/249	188/18639	0.0159574468085106	1.1945014098949	0.460665803769661	0.601371258477549
GO:0005342	organic acid transmembrane transporter activity	3/249	189/18639	0.0158730158730159	1.18818129661503	0.464119778328282	0.604615327091541
GO:0019902	phosphatase binding	3/249	190/18639	0.0157894736842105	1.18192771084337	0.467564148251767	0.60658604877591
GO:0001784	phosphotyrosine residue binding	1/249	47/18639	0.0212765957446809	1.59266854652653	0.468947973243472	0.60658604877591
GO:0043495	protein-membrane adaptor activity	1/249	47/18639	0.0212765957446809	1.59266854652653	0.468947973243472	0.60658604877591
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	7/249	484/18639	0.0144628099173554	1.0826197351389	0.4695209319852	0.60658604877591
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	1/249	48/18639	0.0208333333333333	1.55948795180723	0.476060277173247	0.612498171043518
GO:0016879	ligase activity, forming carbon-nitrogen bonds	1/249	48/18639	0.0208333333333333	1.55948795180723	0.476060277173247	0.612498171043518
GO:0140297	DNA-binding transcription factor binding	7/249	488/18639	0.014344262295082	1.07374580288367	0.478112583578607	0.613872946816977
GO:0016757	glycosyltransferase activity	4/249	267/18639	0.0149812734082397	1.12142953837823	0.479399603575192	0.613931746625193
GO:0003697	single-stranded DNA binding	2/249	121/18639	0.0165289256198347	1.2372796973016	0.482332310411419	0.613931746625193
GO:0001222	transcription corepressor binding	1/249	49/18639	0.0204081632653061	1.52766166707647	0.483077704475913	0.613931746625193
GO:0016763	pentosyltransferase activity	1/249	49/18639	0.0204081632653061	1.52766166707647	0.483077704475913	0.613931746625193
GO:0035254	glutamate receptor binding	1/249	49/18639	0.0204081632653061	1.52766166707647	0.483077704475913	0.613931746625193
GO:0001216	DNA-binding transcription activator activity	7/249	491/18639	0.0142566191446029	1.0671852378966	0.484532860435101	0.614529481527445
GO:0032813	tumor necrosis factor receptor superfamily binding	1/249	50/18639	0.02	1.49710843373494	0.490001515750012	0.619451799243842
GO:0005096	GTPase activator activity	4/249	271/18639	0.014760147601476	1.10487707286711	0.49092307755587	0.619451799243842
GO:0016758	hexosyltransferase activity	3/249	197/18639	0.0152284263959391	1.13993027949361	0.491392052284778	0.619451799243842
GO:0005267	potassium channel activity	2/249	124/18639	0.0161290322580645	1.20734551107656	0.495212277580666	0.622537678443685
GO:0003743	translation initiation factor activity	1/249	51/18639	0.0196078431372549	1.4677533664068	0.496832954911787	0.622537678443685
GO:0005272	sodium channel activity	1/249	51/18639	0.0196078431372549	1.4677533664068	0.496832954911787	0.622537678443685
GO:0004864	protein phosphatase inhibitor activity	1/249	53/18639	0.0188679245283019	1.41236644691975	0.510223610468257	0.63296129807593
GO:0005544	calcium-dependent phospholipid binding	1/249	53/18639	0.0188679245283019	1.41236644691975	0.510223610468257	0.63296129807593
GO:0008146	sulfotransferase activity	1/249	53/18639	0.0188679245283019	1.41236644691975	0.510223610468257	0.63296129807593
GO:0016860	intramolecular oxidoreductase activity	1/249	53/18639	0.0188679245283019	1.41236644691975	0.510223610468257	0.63296129807593
GO:0051018	protein kinase A binding	1/249	53/18639	0.0188679245283019	1.41236644691975	0.510223610468257	0.63296129807593
GO:0031490	chromatin DNA binding	2/249	128/18639	0.015625	1.16961596385542	0.512066904771222	0.633987596383418
GO:0003925	G protein activity	1/249	54/18639	0.0185185185185185	1.38621151271754	0.51678523324849	0.636043363998142
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	1/249	54/18639	0.0185185185185185	1.38621151271754	0.51678523324849	0.636043363998142
GO:0140463	chromatin-protein adaptor activity	1/249	54/18639	0.0185185185185185	1.38621151271754	0.51678523324849	0.636043363998142
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	2/249	130/18639	0.0153846153846154	1.1516218721038	0.520355001746483	0.639176222617727
GO:0004674	protein serine/threonine kinase activity	6/249	433/18639	0.0138568129330254	1.03725757533599	0.521504452922516	0.63932962401503
GO:0008374	O-acyltransferase activity	1/249	55/18639	0.0181818181818182	1.36100766703176	0.523259297112958	0.640223139997031
GO:0019212	phosphatase inhibitor activity	1/249	56/18639	0.0178571428571429	1.33670395869191	0.529646965807473	0.645507239577858
GO:0030170	pyridoxal phosphate binding	1/249	56/18639	0.0178571428571429	1.33670395869191	0.529646965807473	0.645507239577858
GO:0015291	secondary active transmembrane transporter activity	4/249	287/18639	0.0139372822299652	1.04328113849125	0.535900319496103	0.649383335742739
GO:0016504	peptidase activator activity	1/249	57/18639	0.0175438596491228	1.31325301204819	0.535949387672292	0.649383335742739
GO:0070279	vitamin B6 binding	1/249	57/18639	0.0175438596491228	1.31325301204819	0.535949387672292	0.649383335742739
GO:0016779	nucleotidyltransferase activity	2/249	136/18639	0.0147058823529412	1.1008150248051	0.544651075976857	0.657373832513653
GO:0099094	ligand-gated monoatomic cation channel activity	2/249	136/18639	0.0147058823529412	1.1008150248051	0.544651075976857	0.657373832513653
GO:0004879	nuclear receptor activity	1/249	59/18639	0.0169491525423729	1.26873596079232	0.548303008462129	0.657963610154555
GO:0045309	protein phosphorylated amino acid binding	1/249	59/18639	0.0169491525423729	1.26873596079232	0.548303008462129	0.657963610154555
GO:0070888	E-box binding	1/249	59/18639	0.0169491525423729	1.26873596079232	0.548303008462129	0.657963610154555
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	1/249	60/18639	0.0166666666666667	1.24759036144578	0.554356428854645	0.662678949435437
GO:0098531	ligand-modulated transcription factor activity	1/249	60/18639	0.0166666666666667	1.24759036144578	0.554356428854645	0.662678949435437
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	1/249	61/18639	0.0163934426229508	1.22713806043848	0.560329045745499	0.667262069742732
GO:0016836	hydro-lyase activity	1/249	61/18639	0.0163934426229508	1.22713806043848	0.560329045745499	0.667262069742732
GO:0022843	voltage-gated monoatomic cation channel activity	2/249	143/18639	0.013986013986014	1.04692897463982	0.571899838236677	0.678613229774911
GO:1901682	sulfur compound transmembrane transporter activity	1/249	63/18639	0.0158730158730159	1.18818129661503	0.5720361520218	0.678613229774911
GO:0008194	UDP-glycosyltransferase activity	2/249	145/18639	0.0137931034482759	1.03248857498961	0.579465633391925	0.68612249570505
GO:0015293	symporter activity	2/249	146/18639	0.0136986301369863	1.02541673543489	0.583211757234044	0.686909504420329
GO:0019843	rRNA binding	1/249	65/18639	0.0153846153846154	1.1516218721038	0.583432752151882	0.686909504420329
GO:0038024	cargo receptor activity	1/249	65/18639	0.0153846153846154	1.1516218721038	0.583432752151882	0.686909504420329
GO:0008235	metalloexopeptidase activity	1/249	66/18639	0.0151515151515152	1.1341730558598	0.589017184407411	0.692178386196279
GO:0019842	vitamin binding	2/249	150/18639	0.0133333333333333	0.998072289156627	0.597950678158437	0.701355682652002
GO:0016782	transferase activity, transferring sulphur-containing groups	1/249	70/18639	0.0142857142857143	1.06936316695353	0.610619091673773	0.714871131715637
GO:0005506	iron ion binding	2/249	154/18639	0.012987012987013	0.972148333594117	0.612296443897669	0.715492473768063
GO:0042379	chemokine receptor binding	1/249	72/18639	0.0138888888888889	1.03965863453815	0.620992117675233	0.716322723783192
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	3/249	243/18639	0.0123456790123457	0.924141008478358	0.633054890650332	0.716322723783192
GO:0015079	potassium ion transmembrane transporter activity	2/249	160/18639	0.0125	0.935692771084337	0.633079492724879	0.716322723783192
GO:0099106	ion channel regulator activity	2/249	160/18639	0.0125	0.935692771084337	0.633079492724879	0.716322723783192
GO:0019003	GDP binding	1/249	75/18639	0.0133333333333333	0.998072289156627	0.636037834726384	0.716322723783192
GO:0004676	3-phosphoinositide-dependent protein kinase activity	3/249	245/18639	0.0122448979591837	0.916597000245881	0.63855711474513	0.716322723783192
GO:0004711	ribosomal protein S6 kinase activity	3/249	245/18639	0.0122448979591837	0.916597000245881	0.63855711474513	0.716322723783192
GO:0035175	histone H3S10 kinase activity	3/249	245/18639	0.0122448979591837	0.916597000245881	0.63855711474513	0.716322723783192
GO:0035979	histone H2AXS139 kinase activity	3/249	245/18639	0.0122448979591837	0.916597000245881	0.63855711474513	0.716322723783192
GO:0044022	histone H3S28 kinase activity	3/249	245/18639	0.0122448979591837	0.916597000245881	0.63855711474513	0.716322723783192
GO:0044023	histone H4S1 kinase activity	3/249	245/18639	0.0122448979591837	0.916597000245881	0.63855711474513	0.716322723783192
GO:0044024	histone H2AS1 kinase activity	3/249	245/18639	0.0122448979591837	0.916597000245881	0.63855711474513	0.716322723783192
GO:0044025	histone H2BS14 kinase activity	3/249	245/18639	0.0122448979591837	0.916597000245881	0.63855711474513	0.716322723783192
GO:0072354	histone H3T3 kinase activity	3/249	245/18639	0.0122448979591837	0.916597000245881	0.63855711474513	0.716322723783192
GO:0072371	histone H2AS121 kinase activity	3/249	245/18639	0.0122448979591837	0.916597000245881	0.63855711474513	0.716322723783192
GO:0072518	Rho-dependent protein serine/threonine kinase activity	3/249	245/18639	0.0122448979591837	0.916597000245881	0.63855711474513	0.716322723783192
GO:0140823	histone H2BS36 kinase activity	3/249	245/18639	0.0122448979591837	0.916597000245881	0.63855711474513	0.716322723783192
GO:0140855	histone H3S57 kinase activity	3/249	245/18639	0.0122448979591837	0.916597000245881	0.63855711474513	0.716322723783192
GO:0140995	histone H2A kinase activity	3/249	245/18639	0.0122448979591837	0.916597000245881	0.63855711474513	0.716322723783192
GO:0140997	histone H4 kinase activity	3/249	245/18639	0.0122448979591837	0.916597000245881	0.63855711474513	0.716322723783192
GO:0140998	histone H2B kinase activity	3/249	245/18639	0.0122448979591837	0.916597000245881	0.63855711474513	0.716322723783192
GO:1990244	histone H2AT120 kinase activity	3/249	245/18639	0.0122448979591837	0.916597000245881	0.63855711474513	0.716322723783192
GO:0004677	DNA-dependent protein kinase activity	3/249	246/18639	0.0121951219512195	0.912870996179841	0.641286613344453	0.716322723783192
GO:0140857	histone H3T45 kinase activity	3/249	246/18639	0.0121951219512195	0.912870996179841	0.641286613344453	0.716322723783192
GO:0035402	histone H3T11 kinase activity	3/249	247/18639	0.0121457489878543	0.90917516218721	0.644001679555081	0.716322723783192
GO:0035403	histone H3T6 kinase activity	3/249	247/18639	0.0121457489878543	0.90917516218721	0.644001679555081	0.716322723783192
GO:0042393	histone binding	3/249	247/18639	0.0121457489878543	0.90917516218721	0.644001679555081	0.716322723783192
GO:0015081	sodium ion transmembrane transporter activity	2/249	164/18639	0.0121951219512195	0.912870996179841	0.646447130156948	0.7167712859695
GO:0004679	AMP-activated protein kinase activity	3/249	248/18639	0.0120967741935484	0.905509133307423	0.64670229807825	0.7167712859695
GO:0015399	primary active transmembrane transporter activity	2/249	166/18639	0.0120481927710843	0.901872550442735	0.652985649636696	0.722187851472688
GO:0015370	solute:sodium symporter activity	1/249	79/18639	0.0126582278481013	0.947536983376544	0.655177350510196	0.722187851472688
GO:0016835	carbon-oxygen lyase activity	1/249	79/18639	0.0126582278481013	0.947536983376544	0.655177350510196	0.722187851472688
GO:0016874	ligase activity	2/249	167/18639	0.0119760479041916	0.896472116008946	0.65621876888624	0.722187851472688
GO:0016247	channel regulator activity	2/249	168/18639	0.0119047619047619	0.891135972461274	0.659427872381185	0.723580610481933
GO:0000049	tRNA binding	1/249	80/18639	0.0125	0.935692771084337	0.659803473340096	0.723580610481933
GO:0141108	transporter regulator activity	2/249	170/18639	0.0117647058823529	0.880652019844082	0.665774282100368	0.728847635141456
GO:0008135	translation factor activity, RNA binding	1/249	83/18639	0.0120481927710843	0.901872550442735	0.673314214596887	0.735810980575232
GO:0005244	voltage-gated monoatomic ion channel activity	2/249	173/18639	0.0115606936416185	0.865380597534647	0.675115408331169	0.736489536361275
GO:0180051	translation factor activity	1/249	84/18639	0.0119047619047619	0.891135972461274	0.677697958968808	0.737256875356083
GO:0003823	antigen binding	2/249	174/18639	0.0114942528735632	0.860407145824678	0.678181805215371	0.737256875356083
GO:0022832	voltage-gated channel activity	2/249	175/18639	0.0114285714285714	0.855490533562823	0.681224671693878	0.739276861107791
GO:0008081	phosphoric diester hydrolase activity	1/249	87/18639	0.0114942528735632	0.860407145824678	0.690500751673495	0.748042480979619
GO:0016651	oxidoreductase activity, acting on NAD(P)H	1/249	88/18639	0.0113636363636364	0.850629791894852	0.694654768104785	0.751238432057862
GO:0016853	isomerase activity	2/249	180/18639	0.0111111111111111	0.831726907630522	0.696088871494486	0.751486947772594
GO:0003727	single-stranded RNA binding	1/249	89/18639	0.0112359550561798	0.841072153783674	0.698753251353231	0.7520192778496
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	2/249	181/18639	0.0110497237569061	0.827131731345271	0.69899227748841	0.7520192778496
GO:0052689	carboxylic ester hydrolase activity	1/249	92/18639	0.0108695652173913	0.813645887899424	0.710722847543205	0.763323677912151
GO:0015276	ligand-gated monoatomic ion channel activity	2/249	186/18639	0.010752688172043	0.804897007384376	0.713167093447298	0.764632759984732
GO:0051219	phosphoprotein binding	1/249	93/18639	0.010752688172043	0.804897007384376	0.714606495085219	0.764861840365655
GO:0008234	cysteine-type peptidase activity	2/249	187/18639	0.0106951871657754	0.800592745312802	0.715934279350815	0.764970873826898
GO:0022834	ligand-gated channel activity	2/249	188/18639	0.0106382978723404	0.796334273263266	0.718679101668892	0.766591041780151
GO:0008170	N-methyltransferase activity	1/249	98/18639	0.0102040816326531	0.763830833538235	0.733259438584253	0.780808685454905
GO:0005525	GTP binding	4/249	378/18639	0.0105820105820106	0.792120864410021	0.746660519570852	0.793724300191161
GO:0016829	lyase activity	2/249	200/18639	0.01	0.74855421686747	0.749910529846307	0.795823419428734
GO:0019001	guanyl nucleotide binding	4/249	400/18639	0.01	0.74855421686747	0.784931121069603	0.830164439910902
GO:0032561	guanyl ribonucleotide binding	4/249	400/18639	0.01	0.74855421686747	0.784931121069603	0.830164439910902
GO:0004540	RNA nuclease activity	1/249	121/18639	0.00826446280991736	0.618639848650802	0.80458710533723	0.849513288883979
GO:0051087	protein-folding chaperone binding	1/249	134/18639	0.00746268656716418	0.558622549901097	0.836130804181213	0.880675990904862
GO:0005261	monoatomic cation channel activity	3/249	341/18639	0.00879765395894428	0.658552096950853	0.83698522944827	0.880675990904862
GO:0015297	antiporter activity	1/249	135/18639	0.00740740740740741	0.554484605087015	0.838335799034436	0.880675990904862
GO:0140101	catalytic activity, acting on a tRNA	1/249	139/18639	0.00719424460431655	0.538528213573719	0.846864172701646	0.886649737862126
GO:0140767	enzyme-substrate adaptor activity	1/249	139/18639	0.00719424460431655	0.538528213573719	0.846864172701646	0.886649737862126
GO:0046873	metal ion transmembrane transporter activity	4/249	450/18639	0.00888888888888889	0.665381526104418	0.85485347193867	0.893515186749967
GO:0106310	protein serine kinase activity	3/249	361/18639	0.00831024930747922	0.622067216233354	0.863919435686756	0.901481150281833
GO:0008509	monoatomic anion transmembrane transporter activity	1/249	149/18639	0.00671140939597315	0.502385380447966	0.866275261088117	0.902430322068422
GO:0003730	mRNA 3'-UTR binding	2/249	262/18639	0.00763358778625954	0.571415432723259	0.867742418294818	0.902452115026611
GO:0003774	cytoskeletal motor activity	1/249	153/18639	0.0065359477124183	0.489251122135601	0.873334960357215	0.906757096943265
GO:0030695	GTPase regulator activity	4/249	489/18639	0.0081799591002045	0.612314287826151	0.89510347941701	0.925661793769499
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	1/249	167/18639	0.00598802395209581	0.448236058004473	0.895245219525855	0.925661793769499
GO:0060589	nucleoside-triphosphatase regulator activity	4/249	490/18639	0.00816326530612245	0.611064666830588	0.895993146533297	0.925661793769499
GO:0003735	structural constituent of ribosome	1/249	175/18639	0.00571428571428571	0.427745266781411	0.906024965117504	0.934478641707971
GO:0015078	proton transmembrane transporter activity	1/249	185/18639	0.00540540540540541	0.404623901009443	0.917958826740595	0.945224930505167
GO:0016887	ATP hydrolysis activity	3/249	417/18639	0.00719424460431655	0.538528213573719	0.919656213991788	0.945412648321047
GO:0022836	gated channel activity	2/249	318/18639	0.00628930817610063	0.470788815639918	0.927989379507658	0.952410152652596
GO:0008168	methyltransferase activity	1/249	204/18639	0.00490196078431373	0.366938341601701	0.936630547370484	0.959206241613882
GO:0003924	GTPase activity	2/249	331/18639	0.00604229607250755	0.452298620463728	0.93768558875716	0.959206241613882
GO:0005216	monoatomic ion channel activity	3/249	448/18639	0.00669642857142857	0.501263984509466	0.940689881710246	0.959243549738341
GO:0004518	nuclease activity	1/249	209/18639	0.00478468899521531	0.35815991237678	0.940796558397219	0.959243549738341
GO:0016741	transferase activity, transferring one-carbon groups	1/249	215/18639	0.00465116279069767	0.348164752031381	0.945437193404214	0.962402624280961
GO:0045182	translation regulator activity	2/249	356/18639	0.00561797752808989	0.420536076891837	0.952965625567109	0.968486238361361
GO:0140104	molecular carrier activity	1/249	249/18639	0.00401606425702811	0.300624183480912	0.965660645691577	0.977963104394858
GO:0015631	tubulin binding	2/249	385/18639	0.00519480519480519	0.388859333437647	0.966223958507082	0.977963104394858
GO:0140098	catalytic activity, acting on RNA	2/249	387/18639	0.00516795865633075	0.386849724479313	0.966992364441711	0.977963104394858
GO:0008017	microtubule binding	1/249	276/18639	0.0036231884057971	0.271215295966475	0.976241195732941	0.985719265594426
GO:0030371	translation repressor activity	1/249	329/18639	0.00303951367781155	0.227524078075219	0.988488700108596	0.996473261498811
GO:0016755	aminoacyltransferase activity	2/249	496/18639	0.00403225806451613	0.301836377769141	0.990854564149763	0.996505428200185
GO:0061630	ubiquitin protein ligase activity	1/249	353/18639	0.0028328611898017	0.212055018942626	0.991714536718453	0.996505428200185
GO:0061659	ubiquitin-like protein ligase activity	1/249	372/18639	0.00268817204301075	0.201224251846094	0.9936154998667	0.996810405010966
GO:0004842	ubiquitin-protein transferase activity	1/249	449/18639	0.0022271714922049	0.166715861217699	0.997785921184257	0.998536249047936
GO:0019787	ubiquitin-like protein transferase activity	1/249	479/18639	0.00208768267223382	0.156274366778177	0.998536249047936	0.998536249047936