ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0030695 GTPase regulator activity 79/990 489/18639 0.161554192229039 3.04162483733036 4.51416027459695e-19 2.71424527818005e-16 GO:0060589 nucleoside-triphosphatase regulator activity 79/990 490/18639 0.161224489795918 3.03541743970315 5.11639072229981e-19 2.71424527818005e-16 GO:0005085 guanyl-nucleotide exchange factor activity 43/990 230/18639 0.18695652173913 3.5198814229249 3.99354427332794e-13 1.41238349133365e-10 GO:0005096 GTPase activator activity 45/990 271/18639 0.166051660516605 3.12629989936263 8.3702953820495e-12 2.22022085008863e-09 GO:0004674 protein serine/threonine kinase activity 57/990 433/18639 0.131639722863741 2.47841696409826 2.19587397234739e-10 4.38452225691052e-08 GO:0023026 MHC class II protein complex binding 13/990 27/18639 0.481481481481481 9.06498316498316 2.47946593227739e-10 4.38452225691052e-08 GO:0141003 histone H2AX kinase activity 48/990 354/18639 0.135593220338983 2.55285053929122 2.23716191790081e-09 3.39089827841823e-07 GO:0140996 histone H3 kinase activity 48/990 357/18639 0.134453781512605 2.53139801375095 2.96234793562122e-09 3.92881394961764e-07 GO:0035173 histone kinase activity 48/990 360/18639 0.133333333333333 2.51030303030303 3.90731056898857e-09 4.60628501521874e-07 GO:0106310 protein serine kinase activity 47/990 361/18639 0.130193905817175 2.4511961722488 1.21882161200826e-08 1.29316973034076e-06 GO:0023023 MHC protein complex binding 13/990 37/18639 0.351351351351351 6.61498771498772 2.67852399807184e-08 2.58355814723111e-06 GO:0032395 MHC class II receptor activity 7/990 10/18639 0.7 13.1790909090909 1.21728730150471e-07 1.07628485574708e-05 GO:0035591 signaling adaptor activity 23/990 129/18639 0.178294573643411 3.35680056377731 2.85227832015095e-07 2.16875788044308e-05 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 36/990 268/18639 0.134328358208955 2.52903663500678 2.86169748597578e-07 2.16875788044308e-05 GO:0140857 histone H3T45 kinase activity 34/990 246/18639 0.138211382113821 2.60214338507021 3.09682806201692e-07 2.19048971586663e-05 GO:0004679 AMP-activated protein kinase activity 34/990 248/18639 0.137096774193548 2.58115835777126 3.7574055723744e-07 2.49162957018078e-05 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 33/990 243/18639 0.135802469135802 2.55679012345679 6.91655950094194e-07 2.5300217687506e-05 GO:0001217 DNA-binding transcription repressor activity 36/990 278/18639 0.129496402877698 2.4380640941792 7.04014706263516e-07 2.5300217687506e-05 GO:0004676 3-phosphoinositide-dependent protein kinase activity 33/990 245/18639 0.13469387755102 2.53591836734694 8.34597190445533e-07 2.5300217687506e-05 GO:0004711 ribosomal protein S6 kinase activity 33/990 245/18639 0.13469387755102 2.53591836734694 8.34597190445533e-07 2.5300217687506e-05 GO:0035175 histone H3S10 kinase activity 33/990 245/18639 0.13469387755102 2.53591836734694 8.34597190445533e-07 2.5300217687506e-05 GO:0035979 histone H2AXS139 kinase activity 33/990 245/18639 0.13469387755102 2.53591836734694 8.34597190445533e-07 2.5300217687506e-05 GO:0044022 histone H3S28 kinase activity 33/990 245/18639 0.13469387755102 2.53591836734694 8.34597190445533e-07 2.5300217687506e-05 GO:0044023 histone H4S1 kinase activity 33/990 245/18639 0.13469387755102 2.53591836734694 8.34597190445533e-07 2.5300217687506e-05 GO:0044024 histone H2AS1 kinase activity 33/990 245/18639 0.13469387755102 2.53591836734694 8.34597190445533e-07 2.5300217687506e-05 GO:0044025 histone H2BS14 kinase activity 33/990 245/18639 0.13469387755102 2.53591836734694 8.34597190445533e-07 2.5300217687506e-05 GO:0072354 histone H3T3 kinase activity 33/990 245/18639 0.13469387755102 2.53591836734694 8.34597190445533e-07 2.5300217687506e-05 GO:0072371 histone H2AS121 kinase activity 33/990 245/18639 0.13469387755102 2.53591836734694 8.34597190445533e-07 2.5300217687506e-05 GO:0072518 Rho-dependent protein serine/threonine kinase activity 33/990 245/18639 0.13469387755102 2.53591836734694 8.34597190445533e-07 2.5300217687506e-05 GO:0140823 histone H2BS36 kinase activity 33/990 245/18639 0.13469387755102 2.53591836734694 8.34597190445533e-07 2.5300217687506e-05 GO:0140855 histone H3S57 kinase activity 33/990 245/18639 0.13469387755102 2.53591836734694 8.34597190445533e-07 2.5300217687506e-05 GO:0140995 histone H2A kinase activity 33/990 245/18639 0.13469387755102 2.53591836734694 8.34597190445533e-07 2.5300217687506e-05 GO:0140997 histone H4 kinase activity 33/990 245/18639 0.13469387755102 2.53591836734694 8.34597190445533e-07 2.5300217687506e-05 GO:0140998 histone H2B kinase activity 33/990 245/18639 0.13469387755102 2.53591836734694 8.34597190445533e-07 2.5300217687506e-05 GO:1990244 histone H2AT120 kinase activity 33/990 245/18639 0.13469387755102 2.53591836734694 8.34597190445533e-07 2.5300217687506e-05 GO:0004677 DNA-dependent protein kinase activity 33/990 246/18639 0.134146341463415 2.52560975609756 9.15921954201628e-07 2.69942553724424e-05 GO:0035402 histone H3T11 kinase activity 33/990 247/18639 0.133603238866397 2.51538461538462 1.00454331891457e-06 2.80479068781148e-05 GO:0035403 histone H3T6 kinase activity 33/990 247/18639 0.133603238866397 2.51538461538462 1.00454331891457e-06 2.80479068781148e-05 GO:0005543 phospholipid binding 53/990 497/18639 0.106639839034205 2.00773733308945 1.07981588674957e-06 2.93765296369563e-05 GO:0001221 transcription coregulator binding 20/990 115/18639 0.173913043478261 3.27430830039526 2.51125156375485e-06 6.66109477285974e-05 GO:0042605 peptide antigen binding 12/990 45/18639 0.266666666666667 5.02060606060606 2.66092485359668e-06 6.88595431625872e-05 GO:0031267 small GTPase binding 35/990 283/18639 0.123674911660777 2.32846129135882 2.91462523035325e-06 7.36289849858286e-05 GO:0004713 protein tyrosine kinase activity 22/990 140/18639 0.157142857142857 2.95857142857143 4.59075557427353e-06 0.000113274224751261 GO:0051020 GTPase binding 37/990 315/18639 0.117460317460317 2.21145743145743 5.18141030504281e-06 0.0001249426439466 GO:0140375 immune receptor activity 23/990 156/18639 0.147435897435897 2.77581585081585 8.41241803258412e-06 0.000198346122946039 GO:0019207 kinase regulator activity 34/990 287/18639 0.118466898954704 2.23040861577447 1.02953043945109e-05 0.000237463433969046 GO:1990841 promoter-specific chromatin binding 14/990 68/18639 0.205882352941176 3.87620320855615 1.08709765137933e-05 0.000245406512364567 GO:0019209 kinase activator activity 22/990 148/18639 0.148648648648649 2.79864864864865 1.14931598107776e-05 0.000254046719984063 GO:0003779 actin binding 45/990 443/18639 0.101580135440181 1.91247691360558 2.38435763677343e-05 0.000509872617924577 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 48/990 484/18639 0.0991735537190083 1.8671675432006 2.40279273291506e-05 0.000509872617924577 GO:0071813 lipoprotein particle binding 9/990 32/18639 0.28125 5.29517045454545 3.00259350021947e-05 0.000601085227119406 GO:0071814 protein-lipid complex binding 9/990 32/18639 0.28125 5.29517045454545 3.00259350021947e-05 0.000601085227119406 GO:0120015 sterol transfer activity 9/990 32/18639 0.28125 5.29517045454545 3.00259350021947e-05 0.000601085227119406 GO:0001216 DNA-binding transcription activator activity 48/990 491/18639 0.0977596741344195 1.84054804665803 3.46609612440144e-05 0.000681023701479616 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 37/990 349/18639 0.106017191977077 1.99601458713207 5.06040656492042e-05 0.000976198430069194 GO:0042277 peptide binding 29/990 249/18639 0.116465863453815 2.19273457466229 6.14984632679397e-05 0.00116517624155864 GO:0051019 mitogen-activated protein kinase binding 8/990 28/18639 0.285714285714286 5.37922077922078 7.38190087467473e-05 0.00137406961895261 GO:0043178 alcohol binding 15/990 92/18639 0.16304347826087 3.06966403162055 9.54761062536342e-05 0.00174655428853631 GO:0004715 non-membrane spanning protein tyrosine kinase activity 10/990 45/18639 0.222222222222222 4.18383838383838 9.94370764421253e-05 0.00178818200178127 GO:0035401 histone H3Y41 kinase activity 17/990 115/18639 0.147826086956522 2.78316205533597 0.000118514177182897 0.00206136954083694 GO:0140801 histone H2AXY142 kinase activity 17/990 115/18639 0.147826086956522 2.78316205533597 0.000118514177182897 0.00206136954083694 GO:0030295 protein kinase activator activity 19/990 139/18639 0.136690647482014 2.57351209941138 0.000141158286470352 0.0024156280958878 GO:0001784 phosphotyrosine residue binding 10/990 47/18639 0.212765957446809 4.00580270793037 0.000146553098921077 0.00244949494367933 GO:0008432 JUN kinase binding 5/990 11/18639 0.454545454545455 8.55785123966942 0.000147754643162561 0.00244949494367933 GO:0003712 transcription coregulator activity 46/990 495/18639 0.0929292929292929 1.74960514233242 0.000165977550111759 0.0027092643179781 GO:0019902 phosphatase binding 23/990 190/18639 0.121052631578947 2.27909090909091 0.000193932302028129 0.00311760867351279 GO:0061980 regulatory RNA binding 11/990 58/18639 0.189655172413793 3.57068965517241 0.000205164670277036 0.00324895097259605 GO:0019887 protein kinase regulator activity 28/990 255/18639 0.109803921568627 2.06730837789661 0.000224012002490445 0.00346713235537263 GO:0019903 protein phosphatase binding 19/990 144/18639 0.131944444444444 2.48415404040404 0.00022547797598559 0.00346713235537263 GO:0140297 DNA-binding transcription factor binding 45/990 488/18639 0.0922131147540984 1.73612146050671 0.00023137425676252 0.00350697266321477 GO:0120020 cholesterol transfer activity 7/990 25/18639 0.28 5.27163636363636 0.000241312672697117 0.00356942766508984 GO:0035259 nuclear glucocorticoid receptor binding 5/990 12/18639 0.416666666666667 7.84469696969697 0.000242223178026832 0.00356942766508984 GO:0071889 14-3-3 protein binding 8/990 33/18639 0.242424242424242 4.56418732782369 0.000260288000562576 0.00378308998077936 GO:0098531 ligand-modulated transcription factor activity 11/990 60/18639 0.183333333333333 3.45166666666667 0.00028025334612379 0.00401822703023434 GO:0035198 miRNA binding 9/990 42/18639 0.214285714285714 4.03441558441558 0.000295788318552943 0.0041844187464623 GO:0043548 phosphatidylinositol 3-kinase binding 7/990 26/18639 0.269230769230769 5.06888111888112 0.000315186953478795 0.00440017575843423 GO:0008035 high-density lipoprotein particle binding 5/990 13/18639 0.384615384615385 7.24125874125874 0.000376432703882483 0.00518694933531577 GO:1990782 protein tyrosine kinase binding 16/990 117/18639 0.136752136752137 2.57466977466978 0.000459186839814397 0.00624611842362917 GO:0015485 cholesterol binding 10/990 54/18639 0.185185185185185 3.48653198653199 0.00048357170745963 0.00649455166600845 GO:0141052 histone H3 demethylase activity 7/990 28/18639 0.25 4.70681818181818 0.000516929107174932 0.00685577228390754 GO:0031072 heat shock protein binding 17/990 131/18639 0.129770992366412 2.44323386537127 0.000574335051477184 0.007523080118732 GO:0031625 ubiquitin protein ligase binding 30/990 302/18639 0.0993377483443709 1.87025888019265 0.000750804305186061 0.00968798628397191 GO:0005126 cytokine receptor binding 28/990 275/18639 0.101818181818182 1.91695867768595 0.000757872631074145 0.00968798628397191 GO:0032452 histone demethylase activity 7/990 30/18639 0.233333333333333 4.3930303030303 0.000809957852532429 0.0102305390659156 GO:0032934 sterol binding 11/990 68/18639 0.161764705882353 3.04558823529412 0.000851376972089906 0.0106271878516164 GO:0046332 SMAD binding 12/990 79/18639 0.151898734177215 2.85983889528193 0.000898627980159522 0.0110865614761541 GO:0016922 nuclear receptor binding 17/990 137/18639 0.124087591240876 2.33623092236231 0.000959824118735712 0.0113951108800728 GO:0001222 transcription corepressor binding 9/990 49/18639 0.183673469387755 3.45807050092764 0.000976614569552714 0.0113951108800728 GO:0042578 phosphoric ester hydrolase activity 34/990 363/18639 0.09366391184573 1.76343601302279 0.000984245594186298 0.0113951108800728 GO:0070325 lipoprotein particle receptor binding 7/990 31/18639 0.225806451612903 4.25131964809384 0.000998784497061668 0.0113951108800728 GO:0140457 protein demethylase activity 7/990 31/18639 0.225806451612903 4.25131964809384 0.000998784497061668 0.0113951108800728 GO:0004879 nuclear receptor activity 10/990 59/18639 0.169491525423729 3.19106317411402 0.000998817447546435 0.0113951108800728 GO:0045309 protein phosphorylated amino acid binding 10/990 59/18639 0.169491525423729 3.19106317411402 0.000998817447546435 0.0113951108800728 GO:0055102 lipase inhibitor activity 5/990 16/18639 0.3125 5.88352272727273 0.00111791921906226 0.0125368072741027 GO:0017124 SH3 domain binding 15/990 115/18639 0.130434782608696 2.45573122529644 0.00112252280022598 0.0125368072741027 GO:0001540 amyloid-beta binding 12/990 83/18639 0.144578313253012 2.72201533406353 0.00139974110349986 0.0154700553209724 GO:0046965 nuclear retinoid X receptor binding 5/990 17/18639 0.294117647058824 5.53743315508021 0.00151497920612102 0.0165710612133443 GO:0004709 MAP kinase kinase kinase activity 6/990 25/18639 0.24 4.51854545454545 0.00163876781748385 0.0175629561045492 GO:0042974 nuclear retinoic acid receptor binding 6/990 25/18639 0.24 4.51854545454545 0.00163876781748385 0.0175629561045492 GO:0051082 unfolded protein binding 15/990 121/18639 0.12396694214876 2.33395942900075 0.00188335503351758 0.0199823969056215 GO:0015173 aromatic amino acid transmembrane transporter activity 4/990 11/18639 0.363636363636364 6.84628099173554 0.00193250095903643 0.0201929335539989 GO:0044183 protein folding chaperone 11/990 75/18639 0.146666666666667 2.76133333333333 0.00194126222668039 0.0201929335539989 GO:0001223 transcription coactivator binding 8/990 44/18639 0.181818181818182 3.42314049586777 0.00198055606688451 0.0204016503588783 GO:1901981 phosphatidylinositol phosphate binding 20/990 185/18639 0.108108108108108 2.03538083538084 0.00202005902853684 0.0206084868199768 GO:0044389 ubiquitin-like protein ligase binding 30/990 322/18639 0.093167701863354 1.7540937323546 0.00205806803559641 0.0207962874835027 GO:0120013 lipid transfer activity 10/990 65/18639 0.153846153846154 2.8965034965035 0.0021359982895348 0.0213801338226078 GO:0016779 nucleotidyltransferase activity 16/990 136/18639 0.117647058823529 2.21497326203209 0.00233505020358955 0.0231540959440048 GO:0035091 phosphatidylinositol binding 27/990 284/18639 0.0950704225352113 1.78991677336748 0.0025299538090959 0.024854453624544 GO:0005078 MAP-kinase scaffold activity 4/990 12/18639 0.333333333333333 6.27575757575758 0.00277763984954123 0.0263131775032433 GO:0035497 cAMP response element binding 4/990 12/18639 0.333333333333333 6.27575757575758 0.00277763984954123 0.0263131775032433 GO:1990247 N6-methyladenosine-containing RNA reader activity 4/990 12/18639 0.333333333333333 6.27575757575758 0.00277763984954123 0.0263131775032433 GO:1990817 poly(A) RNA polymerase activity 4/990 12/18639 0.333333333333333 6.27575757575758 0.00277763984954123 0.0263131775032433 GO:0043394 proteoglycan binding 7/990 37/18639 0.189189189189189 3.56191646191646 0.00296334631454702 0.0278239861923397 GO:0070888 E-box binding 9/990 59/18639 0.152542372881356 2.87195685670262 0.00372071775426055 0.034628785414653 GO:0060590 ATPase regulator activity 8/990 49/18639 0.163265306122449 3.07384044526902 0.0039894173042178 0.036806710954566 GO:0010314 phosphatidylinositol-5-phosphate binding 5/990 21/18639 0.238095238095238 4.48268398268398 0.004174443870822 0.038181766783984 GO:0035925 mRNA 3'-UTR AU-rich region binding 6/990 30/18639 0.2 3.76545454545455 0.00438096905989478 0.0390605728785576 GO:0051721 protein phosphatase 2A binding 6/990 30/18639 0.2 3.76545454545455 0.00438096905989478 0.0390605728785576 GO:0070566 adenylyltransferase activity 6/990 30/18639 0.2 3.76545454545455 0.00438096905989478 0.0390605728785576 GO:0032451 demethylase activity 7/990 40/18639 0.175 3.29477272727273 0.00467414702654614 0.040985702439384 GO:0140662 ATP-dependent protein folding chaperone 7/990 40/18639 0.175 3.29477272727273 0.00467414702654614 0.040985702439384 GO:0032454 histone H3K9 demethylase activity 4/990 14/18639 0.285714285714286 5.37922077922078 0.00515876459891872 0.044591800684107 GO:0140517 protein-RNA adaptor activity 5/990 22/18639 0.227272727272727 4.27892561983471 0.0051694547447174 0.044591800684107 GO:0004721 phosphoprotein phosphatase activity 18/990 175/18639 0.102857142857143 1.93651948051948 0.00557740546159316 0.047722799957664 GO:0004725 protein tyrosine phosphatase activity 12/990 98/18639 0.122448979591837 2.30538033395176 0.00568876375556785 0.047961016568742 GO:0016791 phosphatase activity 25/990 273/18639 0.0915750915750916 1.72410922410922 0.00577261464605062 0.047961016568742 GO:0002020 protease binding 15/990 136/18639 0.110294117647059 2.07653743315508 0.00578606043430629 0.047961016568742 GO:0140789 histone phosphatase activity 15/990 136/18639 0.110294117647059 2.07653743315508 0.00578606043430629 0.047961016568742 GO:0003725 double-stranded RNA binding 10/990 75/18639 0.133333333333333 2.51030303030303 0.00614539434863823 0.0505446775496525 GO:0005158 insulin receptor binding 5/990 23/18639 0.217391304347826 4.09288537549407 0.00632123566785073 0.0511971835388521 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 5/990 23/18639 0.217391304347826 4.09288537549407 0.00632123566785073 0.0511971835388521 GO:0004712 protein serine/threonine/tyrosine kinase activity 7/990 43/18639 0.162790697674419 3.06490486257928 0.00704000645202625 0.0565867185272716 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 11/990 89/18639 0.123595505617978 2.32696629213483 0.00739921555127409 0.0585863261186702 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 11/990 89/18639 0.123595505617978 2.32696629213483 0.00739921555127409 0.0585863261186702 GO:0001091 RNA polymerase II general transcription initiation factor binding 5/990 24/18639 0.208333333333333 3.92234848484848 0.00764172437446013 0.0591815296445416 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 5/990 24/18639 0.208333333333333 3.92234848484848 0.00764172437446013 0.0591815296445416 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 5/990 24/18639 0.208333333333333 3.92234848484848 0.00764172437446013 0.0591815296445416 GO:0140793 histone H2AXY142 phosphatase activity 11/990 90/18639 0.122222222222222 2.30111111111111 0.00803668518196622 0.0616758670202847 GO:0031490 chromatin DNA binding 14/990 128/18639 0.109375 2.05923295454545 0.00808006174912307 0.0616758670202847 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 4/990 16/18639 0.25 4.70681818181818 0.00861735952230292 0.0653072746654528 GO:0141110 transporter inhibitor activity 7/990 45/18639 0.155555555555556 2.92868686868687 0.00904693852369218 0.0680766083236695 GO:0005154 epidermal growth factor receptor binding 6/990 35/18639 0.171428571428571 3.22753246753247 0.00956218688694712 0.0714470442750063 GO:0019955 cytokine binding 15/990 144/18639 0.104166666666667 1.96117424242424 0.00967059059066744 0.0717517245922948 GO:0003713 transcription coactivator activity 23/990 256/18639 0.08984375 1.69151278409091 0.00980670883660515 0.0717520912484026 GO:0051213 dioxygenase activity 11/990 93/18639 0.118279569892473 2.22688172043011 0.0102071051772821 0.0717520912484026 GO:0051219 phosphoprotein binding 11/990 93/18639 0.118279569892473 2.22688172043011 0.0102071051772821 0.0717520912484026 GO:0030971 receptor tyrosine kinase binding 10/990 81/18639 0.123456790123457 2.32435465768799 0.0104821622464679 0.0717520912484026 GO:0033192 calmodulin-dependent protein phosphatase activity 10/990 81/18639 0.123456790123457 2.32435465768799 0.0104821622464679 0.0717520912484026 GO:0140791 histone H2AXS140 phosphatase activity 10/990 81/18639 0.123456790123457 2.32435465768799 0.0104821622464679 0.0717520912484026 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 10/990 81/18639 0.123456790123457 2.32435465768799 0.0104821622464679 0.0717520912484026 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 10/990 81/18639 0.123456790123457 2.32435465768799 0.0104821622464679 0.0717520912484026 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 10/990 81/18639 0.123456790123457 2.32435465768799 0.0104821622464679 0.0717520912484026 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 10/990 81/18639 0.123456790123457 2.32435465768799 0.0104821622464679 0.0717520912484026 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 10/990 81/18639 0.123456790123457 2.32435465768799 0.0104821622464679 0.0717520912484026 GO:1990439 MAP kinase serine/threonine phosphatase activity 10/990 81/18639 0.123456790123457 2.32435465768799 0.0104821622464679 0.0717520912484026 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 4/990 17/18639 0.235294117647059 4.42994652406417 0.0108027073118973 0.0718463857953061 GO:0008429 phosphatidylethanolamine binding 4/990 17/18639 0.235294117647059 4.42994652406417 0.0108027073118973 0.0718463857953061 GO:0030169 low-density lipoprotein particle binding 4/990 17/18639 0.235294117647059 4.42994652406417 0.0108027073118973 0.0718463857953061 GO:0004112 cyclic-nucleotide phosphodiesterase activity 5/990 26/18639 0.192307692307692 3.62062937062937 0.0108345162368039 0.0718463857953061 GO:0070412 R-SMAD binding 5/990 26/18639 0.192307692307692 3.62062937062937 0.0108345162368039 0.0718463857953061 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 10/990 82/18639 0.121951219512195 2.2960088691796 0.0113872843418002 0.0743046985343261 GO:0033549 MAP kinase phosphatase activity 10/990 82/18639 0.121951219512195 2.2960088691796 0.0113872843418002 0.0743046985343261 GO:0140938 histone H3 methyltransferase activity 7/990 47/18639 0.148936170212766 2.80406189555126 0.011443675603517 0.0743046985343261 GO:0097110 scaffold protein binding 9/990 70/18639 0.128571428571429 2.42064935064935 0.0114853633926762 0.0743046985343261 GO:0005496 steroid binding 12/990 108/18639 0.111111111111111 2.09191919191919 0.0120849017426285 0.0777095802965385 GO:0001786 phosphatidylserine binding 8/990 59/18639 0.135593220338983 2.55285053929122 0.0123290902529778 0.0779980507383319 GO:0015459 potassium channel regulator activity 8/990 59/18639 0.135593220338983 2.55285053929122 0.0123290902529778 0.0779980507383319 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 10/990 83/18639 0.120481927710843 2.26834611171961 0.0123503039811873 0.0779980507383319 GO:0033218 amide binding 22/990 247/18639 0.0890688259109312 1.67692307692308 0.0124812690167459 0.0783587362530613 GO:0001671 ATPase activator activity 5/990 27/18639 0.185185185185185 3.48653198653199 0.0127283908514986 0.0785117702713875 GO:0032266 phosphatidylinositol-3-phosphate binding 7/990 48/18639 0.145833333333333 2.74564393939394 0.0128003344137713 0.0785117702713875 GO:0140693 molecular condensate scaffold activity 7/990 48/18639 0.145833333333333 2.74564393939394 0.0128003344137713 0.0785117702713875 GO:0004896 cytokine receptor activity 11/990 96/18639 0.114583333333333 2.15729166666667 0.0128016364344487 0.0785117702713875 GO:0000900 mRNA regulatory element binding translation repressor activity 4/990 18/18639 0.222222222222222 4.18383838383838 0.0133158388287433 0.0796245868750433 GO:0004706 JUN kinase kinase kinase activity 4/990 18/18639 0.222222222222222 4.18383838383838 0.0133158388287433 0.0796245868750433 GO:0017018 myosin phosphatase activity 10/990 84/18639 0.119047619047619 2.24134199134199 0.0133734018894148 0.0796245868750433 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 3/990 10/18639 0.3 5.64818181818182 0.0135329410454864 0.0796245868750433 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 3/990 10/18639 0.3 5.64818181818182 0.0135329410454864 0.0796245868750433 GO:0051864 histone H3K36 demethylase activity 3/990 10/18639 0.3 5.64818181818182 0.0135329410454864 0.0796245868750433 GO:0070513 death domain binding 3/990 10/18639 0.3 5.64818181818182 0.0135329410454864 0.0796245868750433 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 8/990 60/18639 0.133333333333333 2.51030303030303 0.0135834592124249 0.0796245868750433 GO:0043531 ADP binding 6/990 38/18639 0.157894736842105 2.97272727272727 0.0142186761152339 0.0828901942761714 GO:0097718 disordered domain specific binding 5/990 28/18639 0.178571428571429 3.36201298701299 0.0148339745597583 0.0860046284584895 GO:0070851 growth factor receptor binding 14/990 139/18639 0.100719424460432 1.89627207325049 0.015986731666421 0.0921843603156121 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 5/990 29/18639 0.172413793103448 3.24608150470219 0.0171604761725367 0.0984176498327643 GO:0003953 NAD+ nucleosidase activity 3/990 11/18639 0.272727272727273 5.13471074380165 0.0178831060779051 0.10092540185456 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 3/990 11/18639 0.272727272727273 5.13471074380165 0.0178831060779051 0.10092540185456 GO:0042608 T cell receptor binding 3/990 11/18639 0.272727272727273 5.13471074380165 0.0178831060779051 0.10092540185456 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 13/990 128/18639 0.1015625 1.91214488636364 0.0185880791777465 0.104348952421106 GO:0141108 transporter regulator activity 16/990 170/18639 0.0941176470588235 1.77197860962567 0.0190093669463278 0.106152307000283 GO:0030159 signaling receptor complex adaptor activity 7/990 52/18639 0.134615384615385 2.53444055944056 0.0193905082140313 0.107567744238162 GO:0003727 single-stranded RNA binding 10/990 89/18639 0.112359550561798 2.11542390194076 0.0194656049893752 0.107567744238162 GO:0008187 poly-pyrimidine tract binding 5/990 30/18639 0.166666666666667 3.13787878787879 0.019716377595065 0.108388998074425 GO:0000287 magnesium ion binding 20/990 230/18639 0.0869565217391304 1.63715415019763 0.0210331551763509 0.115031843516022 GO:0140296 general transcription initiation factor binding 7/990 53/18639 0.132075471698113 2.48662092624357 0.0213508602264859 0.116170577950264 GO:0019208 phosphatase regulator activity 12/990 117/18639 0.102564102564103 1.93100233100233 0.0216131258828572 0.116997584498528 GO:0070273 phosphatidylinositol-4-phosphate binding 5/990 31/18639 0.161290322580645 3.0366568914956 0.0225093937950824 0.121210489476203 GO:0004875 complement receptor activity 3/990 12/18639 0.25 4.70681818181818 0.0229182614873597 0.121210489476203 GO:0005527 macrolide binding 3/990 12/18639 0.25 4.70681818181818 0.0229182614873597 0.121210489476203 GO:0035014 phosphatidylinositol 3-kinase regulator activity 3/990 12/18639 0.25 4.70681818181818 0.0229182614873597 0.121210489476203 GO:0008373 sialyltransferase activity 4/990 21/18639 0.19047619047619 3.58614718614719 0.0229625903720233 0.121210489476203 GO:0003714 transcription corepressor activity 18/990 204/18639 0.0882352941176471 1.66122994652406 0.0242479347922659 0.127361677299971 GO:0070717 poly-purine tract binding 5/990 32/18639 0.15625 2.94176136363636 0.0255464409020219 0.133521053187415 GO:0051087 protein-folding chaperone binding 13/990 134/18639 0.0970149253731343 1.82652645861601 0.0260477258955267 0.135473711642911 GO:0031683 G-protein beta/gamma-subunit complex binding 4/990 22/18639 0.181818181818182 3.42314049586777 0.0269166205114247 0.138633661954474 GO:0061133 endopeptidase activator activity 4/990 22/18639 0.181818181818182 3.42314049586777 0.0269166205114247 0.138633661954474 GO:0005516 calmodulin binding 18/990 207/18639 0.0869565217391304 1.63715415019763 0.0275572300741349 0.141247444969358 GO:0001046 core promoter sequence-specific DNA binding 6/990 44/18639 0.136363636363636 2.56735537190083 0.027834488548217 0.141303312677791 GO:0016248 channel inhibitor activity 6/990 44/18639 0.136363636363636 2.56735537190083 0.027834488548217 0.141303312677791 GO:0031994 insulin-like growth factor I binding 3/990 13/18639 0.230769230769231 4.34475524475524 0.0286402870259508 0.143336530823273 GO:0043560 insulin receptor substrate binding 3/990 13/18639 0.230769230769231 4.34475524475524 0.0286402870259508 0.143336530823273 GO:0046974 histone H3K9 methyltransferase activity 3/990 13/18639 0.230769230769231 4.34475524475524 0.0286402870259508 0.143336530823273 GO:0140272 exogenous protein binding 9/990 82/18639 0.109756097560976 2.06640798226164 0.0296041604356913 0.147464855503608 GO:0051015 actin filament binding 18/990 209/18639 0.0861244019138756 1.62148760330579 0.0299446458863094 0.1484638751653 GO:0016504 peptidase activator activity 7/990 57/18639 0.12280701754386 2.31212121212121 0.0305625253704662 0.150822508921231 GO:0008009 chemokine activity 6/990 45/18639 0.133333333333333 2.51030303030303 0.0307248808596824 0.15092175274131 GO:0051117 ATPase binding 9/990 84/18639 0.107142857142857 2.01720779220779 0.0339021065026148 0.165760990780066 GO:0016247 channel regulator activity 15/990 168/18639 0.0892857142857143 1.68100649350649 0.0341578464898146 0.166245298741712 GO:0071933 Arp2/3 complex binding 3/990 14/18639 0.214285714285714 4.03441558441558 0.0350443385969596 0.169781019412667 GO:0019783 ubiquitin-like protein peptidase activity 12/990 127/18639 0.094488188976378 1.77895490336435 0.0377216626126527 0.181921291054657 GO:0001098 basal transcription machinery binding 7/990 60/18639 0.116666666666667 2.19651515151515 0.0390040591234296 0.186411291576391 GO:0001099 basal RNA polymerase II transcription machinery binding 7/990 60/18639 0.116666666666667 2.19651515151515 0.0390040591234296 0.186411291576391 GO:0043130 ubiquitin binding 10/990 100/18639 0.1 1.88272727272727 0.0396098125915879 0.188457449146524 GO:0008234 cysteine-type peptidase activity 16/990 187/18639 0.0855614973262032 1.61088964511424 0.0410607072131596 0.193931195221673 GO:0008081 phosphoric diester hydrolase activity 9/990 87/18639 0.103448275862069 1.94764890282132 0.041125842530515 0.193931195221673 GO:0005402 carbohydrate:monoatomic cation symporter activity 3/990 15/18639 0.2 3.76545454545455 0.0421197983845763 0.196868308749055 GO:0120283 protein serine/threonine kinase binding 3/990 15/18639 0.2 3.76545454545455 0.0421197983845763 0.196868308749055 GO:0015179 L-amino acid transmembrane transporter activity 7/990 62/18639 0.112903225806452 2.12565982404692 0.0454032003302334 0.211228420133063 GO:0099106 ion channel regulator activity 14/990 160/18639 0.0875 1.64738636363636 0.0458324965881713 0.211228420133063 GO:0005112 Notch binding 4/990 26/18639 0.153846153846154 2.8965034965035 0.0465857213111562 0.211228420133063 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 4/990 26/18639 0.153846153846154 2.8965034965035 0.0465857213111562 0.211228420133063 GO:0008143 poly(A) binding 4/990 26/18639 0.153846153846154 2.8965034965035 0.0465857213111562 0.211228420133063 GO:0030247 polysaccharide binding 4/990 26/18639 0.153846153846154 2.8965034965035 0.0465857213111562 0.211228420133063 GO:0050750 low-density lipoprotein particle receptor binding 4/990 26/18639 0.153846153846154 2.8965034965035 0.0465857213111562 0.211228420133063 GO:0004722 protein serine/threonine phosphatase activity 10/990 103/18639 0.0970873786407767 1.8278905560459 0.0469505370634179 0.211976680103347 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 3/990 16/18639 0.1875 3.53011363636364 0.0498511304297163 0.219469084588917 GO:0004708 MAP kinase kinase activity 3/990 16/18639 0.1875 3.53011363636364 0.0498511304297163 0.219469084588917 GO:0005149 interleukin-1 receptor binding 3/990 16/18639 0.1875 3.53011363636364 0.0498511304297163 0.219469084588917 GO:0015923 mannosidase activity 3/990 16/18639 0.1875 3.53011363636364 0.0498511304297163 0.219469084588917 GO:0034450 ubiquitin-ubiquitin ligase activity 3/990 16/18639 0.1875 3.53011363636364 0.0498511304297163 0.219469084588917 GO:0140328 floppase activity 3/990 16/18639 0.1875 3.53011363636364 0.0498511304297163 0.219469084588917 GO:0030544 Hsp70 protein binding 6/990 51/18639 0.117647058823529 2.21497326203209 0.0521474049337141 0.226320584592954 GO:0005319 lipid transporter activity 15/990 178/18639 0.0842696629213483 1.58656792645557 0.0522198445463157 0.226320584592954 GO:0004683 calcium/calmodulin-dependent protein kinase activity 4/990 27/18639 0.148148148148148 2.78922558922559 0.0524739526954445 0.226320584592954 GO:0008266 poly(U) RNA binding 4/990 27/18639 0.148148148148148 2.78922558922559 0.0524739526954445 0.226320584592954 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 4/990 27/18639 0.148148148148148 2.78922558922559 0.0524739526954445 0.226320584592954 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 5/990 39/18639 0.128205128205128 2.41375291375291 0.0540438797501189 0.23214800167966 GO:0032182 ubiquitin-like protein binding 11/990 120/18639 0.0916666666666667 1.72583333333333 0.0543433158176831 0.232492976139362 GO:0004857 enzyme inhibitor activity 30/990 416/18639 0.0721153846153846 1.35773601398601 0.0556061480565798 0.236940253365587 GO:0016887 ATP hydrolysis activity 30/990 417/18639 0.0719424460431655 1.35448005232178 0.0570145762312333 0.241969861525354 GO:0005539 glycosaminoglycan binding 19/990 242/18639 0.0785123966942149 1.47817430503381 0.0577621954443185 0.243188926374304 GO:0019888 protein phosphatase regulator activity 10/990 107/18639 0.0934579439252336 1.75955819881054 0.0580876543986711 0.243188926374304 GO:0044325 transmembrane transporter binding 12/990 136/18639 0.0882352941176471 1.66122994652406 0.0581978909896391 0.243188926374304 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 3/990 17/18639 0.176470588235294 3.32245989304813 0.0582186496692489 0.243188926374304 GO:0050698 proteoglycan sulfotransferase activity 4/990 28/18639 0.142857142857143 2.68961038961039 0.0587472823847255 0.243378045617311 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 4/990 28/18639 0.142857142857143 2.68961038961039 0.0587472823847255 0.243378045617311 GO:0015144 carbohydrate transmembrane transporter activity 5/990 40/18639 0.125 2.35340909090909 0.0591814663235308 0.243378045617311 GO:0030331 nuclear estrogen receptor binding 5/990 40/18639 0.125 2.35340909090909 0.0591814663235308 0.243378045617311 GO:0005246 calcium channel regulator activity 6/990 53/18639 0.113207547169811 2.13138936535163 0.0608969606673192 0.248459718726532 GO:0005544 calcium-dependent phospholipid binding 6/990 53/18639 0.113207547169811 2.13138936535163 0.0608969606673192 0.248459718726532 GO:0004843 cysteine-type deubiquitinase activity 10/990 108/18639 0.0925925925925926 1.74326599326599 0.0611196857564796 0.248459718726532 GO:0042562 hormone binding 9/990 94/18639 0.0957446808510638 1.80261121856867 0.0618279084960898 0.250379430970806 GO:0042054 histone methyltransferase activity 7/990 67/18639 0.104477611940299 1.96702849389417 0.0642099839808586 0.259037235755479 GO:0001530 lipopolysaccharide binding 5/990 41/18639 0.121951219512195 2.2960088691796 0.0645875783548873 0.259573563009604 GO:0001618 virus receptor activity 8/990 81/18639 0.0987654320987654 1.85948372615039 0.0653899923371875 0.260867078318703 GO:0106222 lncRNA binding 4/990 29/18639 0.137931034482759 2.59686520376176 0.0654011713786757 0.260867078318703 GO:0034185 apolipoprotein binding 3/990 18/18639 0.166666666666667 3.13787878787879 0.0671992118373501 0.266038670744136 GO:0050811 GABA receptor binding 3/990 18/18639 0.166666666666667 3.13787878787879 0.0671992118373501 0.266038670744136 GO:0019894 kinesin binding 5/990 42/18639 0.119047619047619 2.24134199134199 0.070260858974337 0.276899820146376 GO:0140313 molecular sequestering activity 6/990 55/18639 0.109090909090909 2.05388429752066 0.0704646102163256 0.276899820146376 GO:0001968 fibronectin binding 4/990 30/18639 0.133333333333333 2.51030303030303 0.0724296011915389 0.282528701706702 GO:0031210 phosphatidylcholine binding 4/990 30/18639 0.133333333333333 2.51030303030303 0.0724296011915389 0.282528701706702 GO:0016279 protein-lysine N-methyltransferase activity 7/990 69/18639 0.101449275362319 1.91001317523057 0.0728782346195465 0.283237388026882 GO:0042826 histone deacetylase binding 11/990 127/18639 0.0866141732283465 1.63070866141732 0.0751491110872028 0.290891456243519 GO:0008200 ion channel inhibitor activity 5/990 43/18639 0.116279069767442 2.1892177589852 0.0761992083506222 0.290891456243519 GO:0005520 insulin-like growth factor binding 3/990 19/18639 0.157894736842105 2.97272727272727 0.0767668310538975 0.290891456243519 GO:0042834 peptidoglycan binding 3/990 19/18639 0.157894736842105 2.97272727272727 0.0767668310538975 0.290891456243519 GO:0043395 heparan sulfate proteoglycan binding 3/990 19/18639 0.157894736842105 2.97272727272727 0.0767668310538975 0.290891456243519 GO:0097001 ceramide binding 3/990 19/18639 0.157894736842105 2.97272727272727 0.0767668310538975 0.290891456243519 GO:1990380 K48-linked deubiquitinase activity 3/990 19/18639 0.157894736842105 2.97272727272727 0.0767668310538975 0.290891456243519 GO:0016278 lysine N-methyltransferase activity 7/990 70/18639 0.1 1.88272727272727 0.07745923914667 0.292470650301128 GO:0101005 deubiquitinase activity 10/990 115/18639 0.0869565217391304 1.63715415019763 0.0851927055373597 0.320253993334011 GO:0016798 hydrolase activity, acting on glycosyl bonds 11/990 130/18639 0.0846153846153846 1.59307692307692 0.0854211876659049 0.320253993334011 GO:0001614 purinergic nucleotide receptor activity 3/990 20/18639 0.15 2.82409090909091 0.0868932313927561 0.320419417472658 GO:0016502 nucleotide receptor activity 3/990 20/18639 0.15 2.82409090909091 0.0868932313927561 0.320419417472658 GO:0030742 GTP-dependent protein binding 3/990 20/18639 0.15 2.82409090909091 0.0868932313927561 0.320419417472658 GO:0042379 chemokine receptor binding 7/990 72/18639 0.0972222222222222 1.83042929292929 0.087113317848041 0.320419417472658 GO:0005178 integrin binding 13/990 161/18639 0.0807453416149068 1.52021456804065 0.0873370189133094 0.320419417472658 GO:0043425 bHLH transcription factor binding 4/990 32/18639 0.125 2.35340909090909 0.0875792941254202 0.320419417472658 GO:0051059 NF-kappaB binding 4/990 32/18639 0.125 2.35340909090909 0.0875792941254202 0.320419417472658 GO:0140303 intramembrane lipid transporter activity 5/990 45/18639 0.111111111111111 2.09191919191919 0.0888591800277213 0.323984845393169 GO:0043539 protein serine/threonine kinase activator activity 7/990 73/18639 0.0958904109589041 1.80535491905355 0.0921849071308723 0.32960635644147 GO:0004197 cysteine-type endopeptidase activity 8/990 88/18639 0.0909090909090909 1.71157024793388 0.095353711548965 0.32960635644147 GO:0000182 rDNA binding 2/990 10/18639 0.2 3.76545454545455 0.0955564475120134 0.32960635644147 GO:0001094 TFIID-class transcription factor complex binding 2/990 10/18639 0.2 3.76545454545455 0.0955564475120134 0.32960635644147 GO:0004445 inositol-polyphosphate 5-phosphatase activity 2/990 10/18639 0.2 3.76545454545455 0.0955564475120134 0.32960635644147 GO:0004955 prostaglandin receptor activity 2/990 10/18639 0.2 3.76545454545455 0.0955564475120134 0.32960635644147 GO:0005345 purine nucleobase transmembrane transporter activity 2/990 10/18639 0.2 3.76545454545455 0.0955564475120134 0.32960635644147 GO:0005528 FK506 binding 2/990 10/18639 0.2 3.76545454545455 0.0955564475120134 0.32960635644147 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 2/990 10/18639 0.2 3.76545454545455 0.0955564475120134 0.32960635644147 GO:0015658 branched-chain amino acid transmembrane transporter activity 2/990 10/18639 0.2 3.76545454545455 0.0955564475120134 0.32960635644147 GO:0015924 mannosyl-oligosaccharide mannosidase activity 2/990 10/18639 0.2 3.76545454545455 0.0955564475120134 0.32960635644147 GO:0030957 Tat protein binding 2/990 10/18639 0.2 3.76545454545455 0.0955564475120134 0.32960635644147 GO:0031996 thioesterase binding 2/990 10/18639 0.2 3.76545454545455 0.0955564475120134 0.32960635644147 GO:0035374 chondroitin sulfate binding 2/990 10/18639 0.2 3.76545454545455 0.0955564475120134 0.32960635644147 GO:0043422 protein kinase B binding 2/990 10/18639 0.2 3.76545454545455 0.0955564475120134 0.32960635644147 GO:1905394 retromer complex binding 2/990 10/18639 0.2 3.76545454545455 0.0955564475120134 0.32960635644147 GO:0030296 protein tyrosine kinase activator activity 4/990 33/18639 0.121212121212121 2.28209366391185 0.0956821468274957 0.32960635644147 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 3/990 21/18639 0.142857142857143 2.68961038961039 0.0975483382295449 0.331726880966497 GO:0035613 RNA stem-loop binding 3/990 21/18639 0.142857142857143 2.68961038961039 0.0975483382295449 0.331726880966497 GO:0051010 microtubule plus-end binding 3/990 21/18639 0.142857142857143 2.68961038961039 0.0975483382295449 0.331726880966497 GO:0072542 protein phosphatase activator activity 3/990 21/18639 0.142857142857143 2.68961038961039 0.0975483382295449 0.331726880966497 GO:0008376 acetylgalactosaminyltransferase activity 4/990 34/18639 0.117647058823529 2.21497326203209 0.104122945014727 0.351829441594348 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 4/990 34/18639 0.117647058823529 2.21497326203209 0.104122945014727 0.351829441594348 GO:0017022 myosin binding 7/990 76/18639 0.0921052631578947 1.73409090909091 0.108363473099839 0.360539273030587 GO:0019838 growth factor binding 11/990 136/18639 0.0808823529411765 1.52279411764706 0.108433116573573 0.360539273030587 GO:0070034 telomerase RNA binding 3/990 22/18639 0.136363636363636 2.56735537190083 0.108700714711353 0.360539273030587 GO:0038187 pattern recognition receptor activity 5/990 48/18639 0.104166666666667 1.96117424242424 0.109745407762653 0.360539273030587 GO:0003697 single-stranded DNA binding 10/990 121/18639 0.0826446280991736 1.55597295266717 0.109832996663638 0.360539273030587 GO:0072341 modified amino acid binding 8/990 91/18639 0.0879120879120879 1.65514485514486 0.110237969433477 0.360539273030587 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 2/990 11/18639 0.181818181818182 3.42314049586777 0.112817190052926 0.360539273030587 GO:0002162 dystroglycan binding 2/990 11/18639 0.181818181818182 3.42314049586777 0.112817190052926 0.360539273030587 GO:0004954 prostanoid receptor activity 2/990 11/18639 0.181818181818182 3.42314049586777 0.112817190052926 0.360539273030587 GO:0005114 type II transforming growth factor beta receptor binding 2/990 11/18639 0.181818181818182 3.42314049586777 0.112817190052926 0.360539273030587 GO:0008199 ferric iron binding 2/990 11/18639 0.181818181818182 3.42314049586777 0.112817190052926 0.360539273030587 GO:0015205 nucleobase transmembrane transporter activity 2/990 11/18639 0.181818181818182 3.42314049586777 0.112817190052926 0.360539273030587 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 2/990 11/18639 0.181818181818182 3.42314049586777 0.112817190052926 0.360539273030587 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 2/990 11/18639 0.181818181818182 3.42314049586777 0.112817190052926 0.360539273030587 GO:0032794 GTPase activating protein binding 2/990 11/18639 0.181818181818182 3.42314049586777 0.112817190052926 0.360539273030587 GO:0043522 leucine zipper domain binding 2/990 11/18639 0.181818181818182 3.42314049586777 0.112817190052926 0.360539273030587 GO:0070990 snRNP binding 2/990 11/18639 0.181818181818182 3.42314049586777 0.112817190052926 0.360539273030587 GO:0097493 structural molecule activity conferring elasticity 2/990 11/18639 0.181818181818182 3.42314049586777 0.112817190052926 0.360539273030587 GO:0016763 pentosyltransferase activity 5/990 49/18639 0.102040816326531 1.92115027829314 0.11719246549461 0.372279059550243 GO:0035254 glutamate receptor binding 5/990 49/18639 0.102040816326531 1.92115027829314 0.11719246549461 0.372279059550243 GO:0005125 cytokine activity 17/990 234/18639 0.0726495726495727 1.36779331779332 0.118756444190678 0.376121156078535 GO:0003887 DNA-directed DNA polymerase activity 3/990 23/18639 0.130434782608696 2.45573122529644 0.120317948267335 0.378805172438109 GO:0043274 phospholipase binding 3/990 23/18639 0.130434782608696 2.45573122529644 0.120317948267335 0.378805172438109 GO:0045296 cadherin binding 23/990 334/18639 0.0688622754491018 1.29648884050082 0.122608540303235 0.384874737460747 GO:0046982 protein heterodimerization activity 25/990 369/18639 0.0677506775067751 1.27556048287756 0.126907441090767 0.389034288586497 GO:0008201 heparin binding 13/990 172/18639 0.0755813953488372 1.42299154334038 0.127317164903119 0.389034288586497 GO:0038024 cargo receptor activity 6/990 65/18639 0.0923076923076923 1.7379020979021 0.130258552925075 0.389034288586497 GO:0004000 adenosine deaminase activity 2/990 12/18639 0.166666666666667 3.13787878787879 0.13079697576604 0.389034288586497 GO:0004859 phospholipase inhibitor activity 2/990 12/18639 0.166666666666667 3.13787878787879 0.13079697576604 0.389034288586497 GO:0005095 GTPase inhibitor activity 2/990 12/18639 0.166666666666667 3.13787878787879 0.13079697576604 0.389034288586497 GO:0015166 polyol transmembrane transporter activity 2/990 12/18639 0.166666666666667 3.13787878787879 0.13079697576604 0.389034288586497 GO:0015269 calcium-activated potassium channel activity 2/990 12/18639 0.166666666666667 3.13787878787879 0.13079697576604 0.389034288586497 GO:0016273 arginine N-methyltransferase activity 2/990 12/18639 0.166666666666667 3.13787878787879 0.13079697576604 0.389034288586497 GO:0016274 protein-arginine N-methyltransferase activity 2/990 12/18639 0.166666666666667 3.13787878787879 0.13079697576604 0.389034288586497 GO:0035197 siRNA binding 2/990 12/18639 0.166666666666667 3.13787878787879 0.13079697576604 0.389034288586497 GO:0070679 inositol 1,4,5 trisphosphate binding 2/990 12/18639 0.166666666666667 3.13787878787879 0.13079697576604 0.389034288586497 GO:0042805 actinin binding 4/990 37/18639 0.108108108108108 2.03538083538084 0.131351895043511 0.389034288586497 GO:0008276 protein methyltransferase activity 8/990 95/18639 0.0842105263157895 1.58545454545455 0.131928143167875 0.389034288586497 GO:0004622 lysophospholipase activity 3/990 24/18639 0.125 2.35340909090909 0.132366991686829 0.389034288586497 GO:0005315 phosphate transmembrane transporter activity 3/990 24/18639 0.125 2.35340909090909 0.132366991686829 0.389034288586497 GO:0015149 hexose transmembrane transporter activity 3/990 24/18639 0.125 2.35340909090909 0.132366991686829 0.389034288586497 GO:0019957 C-C chemokine binding 3/990 24/18639 0.125 2.35340909090909 0.132366991686829 0.389034288586497 GO:0030552 cAMP binding 3/990 24/18639 0.125 2.35340909090909 0.132366991686829 0.389034288586497 GO:0035035 histone acetyltransferase binding 3/990 24/18639 0.125 2.35340909090909 0.132366991686829 0.389034288586497 GO:0050699 WW domain binding 3/990 24/18639 0.125 2.35340909090909 0.132366991686829 0.389034288586497 GO:0055056 D-glucose transmembrane transporter activity 3/990 24/18639 0.125 2.35340909090909 0.132366991686829 0.389034288586497 GO:0070300 phosphatidic acid binding 3/990 24/18639 0.125 2.35340909090909 0.132366991686829 0.389034288586497 GO:0015101 organic cation transmembrane transporter activity 7/990 81/18639 0.0864197530864197 1.62704826038159 0.138427683731756 0.405723128285618 GO:0000146 microfilament motor activity 4/990 38/18639 0.105263157894737 1.98181818181818 0.141019717355861 0.412181598111758 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 6/990 67/18639 0.0895522388059701 1.68602442333786 0.144458591686467 0.417477340941382 GO:0050840 extracellular matrix binding 6/990 67/18639 0.0895522388059701 1.68602442333786 0.144458591686467 0.417477340941382 GO:0017025 TBP-class protein binding 3/990 25/18639 0.12 2.25927272727273 0.144814462928428 0.417477340941382 GO:0019211 phosphatase activator activity 3/990 25/18639 0.12 2.25927272727273 0.144814462928428 0.417477340941382 GO:1901681 sulfur compound binding 19/990 275/18639 0.0690909090909091 1.30079338842975 0.146150362936406 0.417477340941382 GO:0061134 peptidase regulator activity 16/990 226/18639 0.0707964601769911 1.33290426387772 0.148542769439506 0.417477340941382 GO:0008146 sulfotransferase activity 5/990 53/18639 0.0943396226415094 1.77615780445969 0.149233313454064 0.417477340941382 GO:0017046 peptide hormone binding 5/990 53/18639 0.0943396226415094 1.77615780445969 0.149233313454064 0.417477340941382 GO:0038064 collagen receptor activity 5/990 53/18639 0.0943396226415094 1.77615780445969 0.149233313454064 0.417477340941382 GO:0004535 poly(A)-specific ribonuclease activity 2/990 13/18639 0.153846153846154 2.8965034965035 0.149370919173329 0.417477340941382 GO:0005172 vascular endothelial growth factor receptor binding 2/990 13/18639 0.153846153846154 2.8965034965035 0.149370919173329 0.417477340941382 GO:0017154 semaphorin receptor activity 2/990 13/18639 0.153846153846154 2.8965034965035 0.149370919173329 0.417477340941382 GO:0019855 calcium channel inhibitor activity 2/990 13/18639 0.153846153846154 2.8965034965035 0.149370919173329 0.417477340941382 GO:0035325 Toll-like receptor binding 2/990 13/18639 0.153846153846154 2.8965034965035 0.149370919173329 0.417477340941382 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 2/990 13/18639 0.153846153846154 2.8965034965035 0.149370919173329 0.417477340941382 GO:0140410 monoatomic cation:bicarbonate symporter activity 2/990 13/18639 0.153846153846154 2.8965034965035 0.149370919173329 0.417477340941382 GO:0008170 N-methyltransferase activity 8/990 98/18639 0.0816326530612245 1.53692022263451 0.149520631062889 0.417477340941382 GO:0030165 PDZ domain binding 7/990 83/18639 0.0843373493975904 1.58784227820372 0.151479915067446 0.42183776873113 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 10/990 130/18639 0.0769230769230769 1.44825174825175 0.153543666999989 0.426465525358607 GO:0004435 phosphatidylinositol phospholipase C activity 3/990 26/18639 0.115384615384615 2.17237762237762 0.157626907487203 0.428116261624729 GO:0005160 transforming growth factor beta receptor binding 3/990 26/18639 0.115384615384615 2.17237762237762 0.157626907487203 0.428116261624729 GO:0008157 protein phosphatase 1 binding 3/990 26/18639 0.115384615384615 2.17237762237762 0.157626907487203 0.428116261624729 GO:0008198 ferrous iron binding 3/990 26/18639 0.115384615384615 2.17237762237762 0.157626907487203 0.428116261624729 GO:0015145 monosaccharide transmembrane transporter activity 3/990 26/18639 0.115384615384615 2.17237762237762 0.157626907487203 0.428116261624729 GO:0019865 immunoglobulin binding 3/990 26/18639 0.115384615384615 2.17237762237762 0.157626907487203 0.428116261624729 GO:0052742 phosphatidylinositol kinase activity 3/990 26/18639 0.115384615384615 2.17237762237762 0.157626907487203 0.428116261624729 GO:0003925 G protein activity 5/990 54/18639 0.0925925925925926 1.74326599326599 0.157769517714674 0.428116261624729 GO:0140463 chromatin-protein adaptor activity 5/990 54/18639 0.0925925925925926 1.74326599326599 0.157769517714674 0.428116261624729 GO:0004860 protein kinase inhibitor activity 7/990 84/18639 0.0833333333333333 1.56893939393939 0.158213711824089 0.428226398585098 GO:0003730 mRNA 3'-UTR binding 18/990 262/18639 0.0687022900763359 1.29347675225538 0.159362991419554 0.430239526453298 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 4/990 40/18639 0.1 1.88272727272727 0.161157407166531 0.432881035452378 GO:0050997 quaternary ammonium group binding 4/990 40/18639 0.1 1.88272727272727 0.161157407166531 0.432881035452378 GO:0001664 G protein-coupled receptor binding 20/990 297/18639 0.0673400673400673 1.26782981328436 0.164651946632049 0.436917593092476 GO:0016782 transferase activity, transferring sulphur-containing groups 6/990 70/18639 0.0857142857142857 1.61376623376623 0.167006180727265 0.436917593092476 GO:0004065 arylsulfatase activity 2/990 14/18639 0.142857142857143 2.68961038961039 0.16842534926939 0.436917593092476 GO:0004705 JUN kinase activity 2/990 14/18639 0.142857142857143 2.68961038961039 0.16842534926939 0.436917593092476 GO:0005347 ATP transmembrane transporter activity 2/990 14/18639 0.142857142857143 2.68961038961039 0.16842534926939 0.436917593092476 GO:0005545 1-phosphatidylinositol binding 2/990 14/18639 0.142857142857143 2.68961038961039 0.16842534926939 0.436917593092476 GO:0019992 diacylglycerol binding 2/990 14/18639 0.142857142857143 2.68961038961039 0.16842534926939 0.436917593092476 GO:0032036 myosin heavy chain binding 2/990 14/18639 0.142857142857143 2.68961038961039 0.16842534926939 0.436917593092476 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 2/990 14/18639 0.142857142857143 2.68961038961039 0.16842534926939 0.436917593092476 GO:0043176 amine binding 2/990 14/18639 0.142857142857143 2.68961038961039 0.16842534926939 0.436917593092476 GO:0044548 S100 protein binding 2/990 14/18639 0.142857142857143 2.68961038961039 0.16842534926939 0.436917593092476 GO:0046030 inositol trisphosphate phosphatase activity 2/990 14/18639 0.142857142857143 2.68961038961039 0.16842534926939 0.436917593092476 GO:0061665 SUMO ligase activity 2/990 14/18639 0.142857142857143 2.68961038961039 0.16842534926939 0.436917593092476 GO:1901474 azole transmembrane transporter activity 2/990 14/18639 0.142857142857143 2.68961038961039 0.16842534926939 0.436917593092476 GO:0001727 lipid kinase activity 4/990 41/18639 0.0975609756097561 1.83680709534368 0.171597388659682 0.440834937936858 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 4/990 41/18639 0.0975609756097561 1.83680709534368 0.171597388659682 0.440834937936858 GO:0015175 neutral L-amino acid transmembrane transporter activity 4/990 41/18639 0.0975609756097561 1.83680709534368 0.171597388659682 0.440834937936858 GO:0042169 SH2 domain binding 4/990 41/18639 0.0975609756097561 1.83680709534368 0.171597388659682 0.440834937936858 GO:0016209 antioxidant activity 7/990 86/18639 0.0813953488372093 1.53245243128964 0.172079016613213 0.441004436296181 GO:0061135 endopeptidase regulator activity 13/990 184/18639 0.0706521739130435 1.33018774703557 0.180849770643489 0.462365317235523 GO:0008307 structural constituent of muscle 4/990 42/18639 0.0952380952380952 1.79307359307359 0.182264391784455 0.462450690960248 GO:0051879 Hsp90 protein binding 4/990 42/18639 0.0952380952380952 1.79307359307359 0.182264391784455 0.462450690960248 GO:0046625 sphingolipid binding 3/990 28/18639 0.107142857142857 2.01720779220779 0.184213876170346 0.462450690960248 GO:0046875 ephrin receptor binding 3/990 28/18639 0.107142857142857 2.01720779220779 0.184213876170346 0.462450690960248 GO:0051119 sugar transmembrane transporter activity 3/990 28/18639 0.107142857142857 2.01720779220779 0.184213876170346 0.462450690960248 GO:0051959 dynein light intermediate chain binding 3/990 28/18639 0.107142857142857 2.01720779220779 0.184213876170346 0.462450690960248 GO:0000774 adenyl-nucleotide exchange factor activity 2/990 15/18639 0.133333333333333 2.51030303030303 0.187856972482438 0.462450690960248 GO:0004559 alpha-mannosidase activity 2/990 15/18639 0.133333333333333 2.51030303030303 0.187856972482438 0.462450690960248 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/990 15/18639 0.133333333333333 2.51030303030303 0.187856972482438 0.462450690960248 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/990 15/18639 0.133333333333333 2.51030303030303 0.187856972482438 0.462450690960248 GO:0004953 icosanoid receptor activity 2/990 15/18639 0.133333333333333 2.51030303030303 0.187856972482438 0.462450690960248 GO:0005041 low-density lipoprotein particle receptor activity 2/990 15/18639 0.133333333333333 2.51030303030303 0.187856972482438 0.462450690960248 GO:0050700 CARD domain binding 2/990 15/18639 0.133333333333333 2.51030303030303 0.187856972482438 0.462450690960248 GO:0050780 dopamine receptor binding 2/990 15/18639 0.133333333333333 2.51030303030303 0.187856972482438 0.462450690960248 GO:0061578 K63-linked deubiquitinase activity 2/990 15/18639 0.133333333333333 2.51030303030303 0.187856972482438 0.462450690960248 GO:0140776 protein-containing complex destabilizing activity 2/990 15/18639 0.133333333333333 2.51030303030303 0.187856972482438 0.462450690960248 GO:0015291 secondary active transmembrane transporter activity 19/990 287/18639 0.0662020905923345 1.2464048146975 0.190902371757233 0.468859760264871 GO:0003785 actin monomer binding 3/990 29/18639 0.103448275862069 1.94764890282132 0.197923034415539 0.480540822688527 GO:0004629 phospholipase C activity 3/990 29/18639 0.103448275862069 1.94764890282132 0.197923034415539 0.480540822688527 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 3/990 29/18639 0.103448275862069 1.94764890282132 0.197923034415539 0.480540822688527 GO:0010484 histone H3 acetyltransferase activity 3/990 29/18639 0.103448275862069 1.94764890282132 0.197923034415539 0.480540822688527 GO:0097472 cyclin-dependent protein kinase activity 3/990 29/18639 0.103448275862069 1.94764890282132 0.197923034415539 0.480540822688527 GO:0019210 kinase inhibitor activity 7/990 90/18639 0.0777777777777778 1.46434343434343 0.201291873552968 0.486929076285655 GO:0008013 beta-catenin binding 8/990 106/18639 0.0754716981132075 1.42092624356775 0.201472068321774 0.486929076285655 GO:0070063 RNA polymerase binding 5/990 59/18639 0.0847457627118644 1.59553158705701 0.203189988303679 0.489964949068645 GO:0043014 alpha-tubulin binding 4/990 44/18639 0.0909090909090909 1.71157024793388 0.204217178004958 0.49121840623314 GO:0140767 enzyme-substrate adaptor activity 10/990 139/18639 0.0719424460431655 1.35448005232178 0.204635754528792 0.49121840623314 GO:0004707 MAP kinase activity 2/990 16/18639 0.125 2.35340909090909 0.207572092775684 0.493798184831841 GO:0005159 insulin-like growth factor receptor binding 2/990 16/18639 0.125 2.35340909090909 0.207572092775684 0.493798184831841 GO:0030275 LRR domain binding 2/990 16/18639 0.125 2.35340909090909 0.207572092775684 0.493798184831841 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/990 16/18639 0.125 2.35340909090909 0.207572092775684 0.493798184831841 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 7/990 91/18639 0.0769230769230769 1.44825174825175 0.208879698896259 0.495797227134073 GO:0140030 modification-dependent protein binding 12/990 173/18639 0.069364161849711 1.30593799264319 0.209726739091355 0.49658962611147 GO:0005525 GTP binding 24/990 378/18639 0.0634920634920635 1.1953823953824 0.210149615574034 0.49658962611147 GO:0015215 nucleotide transmembrane transporter activity 3/990 30/18639 0.1 1.88272727272727 0.211866749218205 0.497324382567512 GO:0031624 ubiquitin conjugating enzyme binding 3/990 30/18639 0.1 1.88272727272727 0.211866749218205 0.497324382567512 GO:0048019 receptor antagonist activity 3/990 30/18639 0.1 1.88272727272727 0.211866749218205 0.497324382567512 GO:0003823 antigen binding 12/990 174/18639 0.0689655172413793 1.29843260188088 0.215221871393261 0.504084780459712 GO:0030276 clathrin binding 4/990 46/18639 0.0869565217391304 1.63715415019763 0.226890516872724 0.51463224773232 GO:0019001 guanyl nucleotide binding 25/990 400/18639 0.0625 1.17670454545455 0.227049703716343 0.51463224773232 GO:0032561 guanyl ribonucleotide binding 25/990 400/18639 0.0625 1.17670454545455 0.227049703716343 0.51463224773232 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 2/990 17/18639 0.117647058823529 2.21497326203209 0.227485885189876 0.51463224773232 GO:0005092 GDP-dissociation inhibitor activity 2/990 17/18639 0.117647058823529 2.21497326203209 0.227485885189876 0.51463224773232 GO:0008484 sulfuric ester hydrolase activity 2/990 17/18639 0.117647058823529 2.21497326203209 0.227485885189876 0.51463224773232 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/990 17/18639 0.117647058823529 2.21497326203209 0.227485885189876 0.51463224773232 GO:0015278 intracellularly gated calcium channel activity 2/990 17/18639 0.117647058823529 2.21497326203209 0.227485885189876 0.51463224773232 GO:0019198 transmembrane receptor protein phosphatase activity 2/990 17/18639 0.117647058823529 2.21497326203209 0.227485885189876 0.51463224773232 GO:0032183 SUMO binding 2/990 17/18639 0.117647058823529 2.21497326203209 0.227485885189876 0.51463224773232 GO:0036041 long-chain fatty acid binding 2/990 17/18639 0.117647058823529 2.21497326203209 0.227485885189876 0.51463224773232 GO:0038191 neuropilin binding 2/990 17/18639 0.117647058823529 2.21497326203209 0.227485885189876 0.51463224773232 GO:0045236 CXCR chemokine receptor binding 2/990 17/18639 0.117647058823529 2.21497326203209 0.227485885189876 0.51463224773232 GO:0051787 misfolded protein binding 2/990 17/18639 0.117647058823529 2.21497326203209 0.227485885189876 0.51463224773232 GO:0070403 NAD+ binding 2/990 17/18639 0.117647058823529 2.21497326203209 0.227485885189876 0.51463224773232 GO:1990226 histone methyltransferase binding 2/990 17/18639 0.117647058823529 2.21497326203209 0.227485885189876 0.51463224773232 GO:0030246 carbohydrate binding 18/990 280/18639 0.0642857142857143 1.21032467532468 0.234086195939787 0.528437135940668 GO:0005504 fatty acid binding 4/990 47/18639 0.0851063829787234 1.60232108317215 0.238458284135446 0.537163990377301 GO:0042393 histone binding 16/990 247/18639 0.0647773279352227 1.21958041958042 0.241159468583497 0.542097873235361 GO:0033293 monocarboxylic acid binding 6/990 79/18639 0.0759493670886076 1.42991944764097 0.24223453236741 0.543363295648672 GO:0005200 structural constituent of cytoskeleton 8/990 112/18639 0.0714285714285714 1.34480519480519 0.244539577172884 0.547376564093734 GO:0008525 phosphatidylcholine transporter activity 2/990 18/18639 0.111111111111111 2.09191919191919 0.247521719358941 0.548268359582123 GO:0015172 acidic amino acid transmembrane transporter activity 2/990 18/18639 0.111111111111111 2.09191919191919 0.247521719358941 0.548268359582123 GO:0016854 racemase and epimerase activity 2/990 18/18639 0.111111111111111 2.09191919191919 0.247521719358941 0.548268359582123 GO:0030228 lipoprotein particle receptor activity 2/990 18/18639 0.111111111111111 2.09191919191919 0.247521719358941 0.548268359582123 GO:0035615 clathrin adaptor activity 2/990 18/18639 0.111111111111111 2.09191919191919 0.247521719358941 0.548268359582123 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 4/990 48/18639 0.0833333333333333 1.56893939393939 0.250159454714791 0.552956628025819 GO:0061659 ubiquitin-like protein ligase activity 23/990 372/18639 0.0618279569892473 1.16405180840665 0.25462446003089 0.557408211825434 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 3/990 33/18639 0.0909090909090909 1.71157024793388 0.254800172229346 0.557408211825434 GO:0019239 deaminase activity 3/990 33/18639 0.0909090909090909 1.71157024793388 0.254800172229346 0.557408211825434 GO:0019956 chemokine binding 3/990 33/18639 0.0909090909090909 1.71157024793388 0.254800172229346 0.557408211825434 GO:0140416 transcription regulator inhibitor activity 3/990 33/18639 0.0909090909090909 1.71157024793388 0.254800172229346 0.557408211825434 GO:0019787 ubiquitin-like protein transferase activity 29/990 479/18639 0.0605427974947808 1.13985576010628 0.25822963306818 0.560402108763805 GO:0005004 GPI-linked ephrin receptor activity 4/990 49/18639 0.0816326530612245 1.53692022263451 0.261978742645474 0.560402108763805 GO:0005008 hepatocyte growth factor receptor activity 4/990 49/18639 0.0816326530612245 1.53692022263451 0.261978742645474 0.560402108763805 GO:0005009 insulin receptor activity 4/990 49/18639 0.0816326530612245 1.53692022263451 0.261978742645474 0.560402108763805 GO:0005011 macrophage colony-stimulating factor receptor activity 4/990 49/18639 0.0816326530612245 1.53692022263451 0.261978742645474 0.560402108763805 GO:0005018 platelet-derived growth factor alpha-receptor activity 4/990 49/18639 0.0816326530612245 1.53692022263451 0.261978742645474 0.560402108763805 GO:0005020 stem cell factor receptor activity 4/990 49/18639 0.0816326530612245 1.53692022263451 0.261978742645474 0.560402108763805 GO:0008288 boss receptor activity 4/990 49/18639 0.0816326530612245 1.53692022263451 0.261978742645474 0.560402108763805 GO:0036332 placental growth factor receptor activity 4/990 49/18639 0.0816326530612245 1.53692022263451 0.261978742645474 0.560402108763805 GO:0038062 protein tyrosine kinase collagen receptor activity 4/990 49/18639 0.0816326530612245 1.53692022263451 0.261978742645474 0.560402108763805 GO:0060175 brain-derived neurotrophic factor receptor activity 4/990 49/18639 0.0816326530612245 1.53692022263451 0.261978742645474 0.560402108763805 GO:0005346 purine ribonucleotide transmembrane transporter activity 2/990 19/18639 0.105263157894737 1.98181818181818 0.26761052974777 0.566736071980806 GO:0030506 ankyrin binding 2/990 19/18639 0.105263157894737 1.98181818181818 0.26761052974777 0.566736071980806 GO:0034987 immunoglobulin receptor binding 2/990 19/18639 0.105263157894737 1.98181818181818 0.26761052974777 0.566736071980806 GO:0042800 histone H3K4 methyltransferase activity 2/990 19/18639 0.105263157894737 1.98181818181818 0.26761052974777 0.566736071980806 GO:0140036 ubiquitin-modified protein reader activity 2/990 19/18639 0.105263157894737 1.98181818181818 0.26761052974777 0.566736071980806 GO:0030332 cyclin binding 3/990 34/18639 0.0882352941176471 1.66122994652406 0.269381839379148 0.568218949465757 GO:0052866 phosphatidylinositol phosphate phosphatase activity 3/990 34/18639 0.0882352941176471 1.66122994652406 0.269381839379148 0.568218949465757 GO:0005006 epidermal growth factor receptor activity 4/990 50/18639 0.08 1.50618181818182 0.273901083422253 0.570941158174874 GO:0005007 fibroblast growth factor receptor activity 4/990 50/18639 0.08 1.50618181818182 0.273901083422253 0.570941158174874 GO:0005017 platelet-derived growth factor receptor activity 4/990 50/18639 0.08 1.50618181818182 0.273901083422253 0.570941158174874 GO:0005019 platelet-derived growth factor beta-receptor activity 4/990 50/18639 0.08 1.50618181818182 0.273901083422253 0.570941158174874 GO:0032813 tumor necrosis factor receptor superfamily binding 4/990 50/18639 0.08 1.50618181818182 0.273901083422253 0.570941158174874 GO:0048020 CCR chemokine receptor binding 4/990 50/18639 0.08 1.50618181818182 0.273901083422253 0.570941158174874 GO:0015294 solute:monoatomic cation symporter activity 8/990 116/18639 0.0689655172413793 1.29843260188088 0.274794471533686 0.571680263327924 GO:0004842 ubiquitin-protein transferase activity 27/990 449/18639 0.0601336302895323 1.13215225754201 0.279155795422347 0.579617023372035 GO:0016500 protein-hormone receptor activity 5/990 67/18639 0.0746268656716418 1.40502035278155 0.283126924320453 0.583631612941602 GO:0010485 histone H4 acetyltransferase activity 3/990 35/18639 0.0857142857142857 1.61376623376623 0.284052951987883 0.583631612941602 GO:0034061 DNA polymerase activity 3/990 35/18639 0.0857142857142857 1.61376623376623 0.284052951987883 0.583631612941602 GO:0061631 ubiquitin conjugating enzyme activity 3/990 35/18639 0.0857142857142857 1.61376623376623 0.284052951987883 0.583631612941602 GO:0140566 histone reader activity 3/990 35/18639 0.0857142857142857 1.61376623376623 0.284052951987883 0.583631612941602 GO:0005010 insulin-like growth factor receptor activity 4/990 51/18639 0.0784313725490196 1.47664884135472 0.285911673344093 0.583631612941602 GO:0005021 vascular endothelial growth factor receptor activity 4/990 51/18639 0.0784313725490196 1.47664884135472 0.285911673344093 0.583631612941602 GO:0005030 neurotrophin receptor activity 4/990 51/18639 0.0784313725490196 1.47664884135472 0.285911673344093 0.583631612941602 GO:0016004 phospholipase activator activity 2/990 20/18639 0.1 1.88272727272727 0.287690229564993 0.583631612941602 GO:0016505 peptidase activator activity involved in apoptotic process 2/990 20/18639 0.1 1.88272727272727 0.287690229564993 0.583631612941602 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/990 20/18639 0.1 1.88272727272727 0.287690229564993 0.583631612941602 GO:0052745 inositol phosphate phosphatase activity 2/990 20/18639 0.1 1.88272727272727 0.287690229564993 0.583631612941602 GO:0031406 carboxylic acid binding 12/990 187/18639 0.0641711229946524 1.20816723383568 0.291544624448153 0.590322226220402 GO:0005548 phospholipid transporter activity 5/990 68/18639 0.0735294117647059 1.38435828877005 0.29354865478872 0.592120005191696 GO:0030145 manganese ion binding 5/990 68/18639 0.0735294117647059 1.38435828877005 0.29354865478872 0.592120005191696 GO:0003774 cytoskeletal motor activity 10/990 153/18639 0.065359477124183 1.23054070112894 0.295623614909754 0.59404669586979 GO:0061775 cohesin loader activity 10/990 153/18639 0.065359477124183 1.23054070112894 0.295623614909754 0.59404669586979 GO:0140597 protein carrier chaperone 12/990 188/18639 0.0638297872340425 1.20174081237911 0.297731776650425 0.595890511380679 GO:0015171 amino acid transmembrane transporter activity 7/990 102/18639 0.0686274509803922 1.29206773618538 0.298249015318062 0.595890511380679 GO:0000993 RNA polymerase II complex binding 3/990 36/18639 0.0833333333333333 1.56893939393939 0.298787702219153 0.595890511380679 GO:0044390 ubiquitin-like protein conjugating enzyme binding 3/990 36/18639 0.0833333333333333 1.56893939393939 0.298787702219153 0.595890511380679 GO:0043177 organic acid binding 12/990 189/18639 0.0634920634920635 1.1953823953824 0.303955108370352 0.60485195712521 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 2/990 21/18639 0.0952380952380952 1.79307359307359 0.307705165495041 0.60485195712521 GO:0005123 death receptor binding 2/990 21/18639 0.0952380952380952 1.79307359307359 0.307705165495041 0.60485195712521 GO:0009931 calcium-dependent protein serine/threonine kinase activity 2/990 21/18639 0.0952380952380952 1.79307359307359 0.307705165495041 0.60485195712521 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/990 21/18639 0.0952380952380952 1.79307359307359 0.307705165495041 0.60485195712521 GO:0070182 DNA polymerase binding 2/990 21/18639 0.0952380952380952 1.79307359307359 0.307705165495041 0.60485195712521 GO:0140312 cargo adaptor activity 2/990 21/18639 0.0952380952380952 1.79307359307359 0.307705165495041 0.60485195712521 GO:0003924 GTPase activity 20/990 331/18639 0.0604229607250755 1.13759956056029 0.307841712391719 0.60485195712521 GO:0004864 protein phosphatase inhibitor activity 4/990 53/18639 0.0754716981132075 1.42092624356775 0.310139898025771 0.606000795221626 GO:0005003 ephrin receptor activity 4/990 53/18639 0.0754716981132075 1.42092624356775 0.310139898025771 0.606000795221626 GO:0005005 transmembrane-ephrin receptor activity 4/990 53/18639 0.0754716981132075 1.42092624356775 0.310139898025771 0.606000795221626 GO:0030551 cyclic nucleotide binding 3/990 37/18639 0.0810810810810811 1.52653562653563 0.313561449911121 0.611560107271507 GO:0016755 aminoacyltransferase activity 29/990 496/18639 0.0584677419354839 1.10078812316716 0.32261991715999 0.616602011487883 GO:0061630 ubiquitin protein ligase activity 21/990 353/18639 0.0594900849858357 1.12003605459696 0.327220931571892 0.616602011487883 GO:0008970 phospholipase A1 activity 2/990 22/18639 0.0909090909090909 1.71157024793388 0.327605610573409 0.616602011487883 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 2/990 22/18639 0.0909090909090909 1.71157024793388 0.327605610573409 0.616602011487883 GO:0032931 histone H3K56 acetyltransferase activity 2/990 22/18639 0.0909090909090909 1.71157024793388 0.327605610573409 0.616602011487883 GO:0043992 histone H3K9 acetyltransferase activity 2/990 22/18639 0.0909090909090909 1.71157024793388 0.327605610573409 0.616602011487883 GO:0043993 histone H3K18 acetyltransferase activity 2/990 22/18639 0.0909090909090909 1.71157024793388 0.327605610573409 0.616602011487883 GO:0043994 histone H3K23 acetyltransferase activity 2/990 22/18639 0.0909090909090909 1.71157024793388 0.327605610573409 0.616602011487883 GO:0043999 histone H2AK5 acetyltransferase activity 2/990 22/18639 0.0909090909090909 1.71157024793388 0.327605610573409 0.616602011487883 GO:0044012 histone H2AK9 acetyltransferase activity 2/990 22/18639 0.0909090909090909 1.71157024793388 0.327605610573409 0.616602011487883 GO:0044014 histone H2BK5 acetyltransferase activity 2/990 22/18639 0.0909090909090909 1.71157024793388 0.327605610573409 0.616602011487883 GO:0044015 histone H2BK12 acetyltransferase activity 2/990 22/18639 0.0909090909090909 1.71157024793388 0.327605610573409 0.616602011487883 GO:0044016 histone H3K4 acetyltransferase activity 2/990 22/18639 0.0909090909090909 1.71157024793388 0.327605610573409 0.616602011487883 GO:0044017 histone H3K27 acetyltransferase activity 2/990 22/18639 0.0909090909090909 1.71157024793388 0.327605610573409 0.616602011487883 GO:0044018 histone H3K36 acetyltransferase activity 2/990 22/18639 0.0909090909090909 1.71157024793388 0.327605610573409 0.616602011487883 GO:0046972 histone H4K16 acetyltransferase activity 2/990 22/18639 0.0909090909090909 1.71157024793388 0.327605610573409 0.616602011487883 GO:0050321 tau-protein kinase activity 2/990 22/18639 0.0909090909090909 1.71157024793388 0.327605610573409 0.616602011487883 GO:0140035 ubiquitin-like protein reader activity 2/990 22/18639 0.0909090909090909 1.71157024793388 0.327605610573409 0.616602011487883 GO:0140908 histone H3K122 acetyltransferase activity 2/990 22/18639 0.0909090909090909 1.71157024793388 0.327605610573409 0.616602011487883 GO:0042162 telomeric DNA binding 3/990 38/18639 0.0789473684210526 1.48636363636364 0.328350741273001 0.616602011487883 GO:0042887 amide transmembrane transporter activity 3/990 38/18639 0.0789473684210526 1.48636363636364 0.328350741273001 0.616602011487883 GO:0008374 O-acyltransferase activity 4/990 55/18639 0.0727272727272727 1.36925619834711 0.334551451586827 0.627136201649511 GO:0005518 collagen binding 5/990 72/18639 0.0694444444444444 1.3074494949495 0.335784854992856 0.628338150171817 GO:0043021 ribonucleoprotein complex binding 11/990 177/18639 0.0621468926553672 1.17005649717514 0.34005114452422 0.635201169613023 GO:0019212 phosphatase inhibitor activity 4/990 56/18639 0.0714285714285714 1.34480519480519 0.346792623877576 0.635405995779934 GO:0000295 adenine nucleotide transmembrane transporter activity 2/990 23/18639 0.0869565217391304 1.63715415019763 0.347347292697796 0.635405995779934 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 2/990 23/18639 0.0869565217391304 1.63715415019763 0.347347292697796 0.635405995779934 GO:0004602 glutathione peroxidase activity 2/990 23/18639 0.0869565217391304 1.63715415019763 0.347347292697796 0.635405995779934 GO:0005212 structural constituent of eye lens 2/990 23/18639 0.0869565217391304 1.63715415019763 0.347347292697796 0.635405995779934 GO:0005283 amino acid:sodium symporter activity 2/990 23/18639 0.0869565217391304 1.63715415019763 0.347347292697796 0.635405995779934 GO:0017134 fibroblast growth factor binding 2/990 23/18639 0.0869565217391304 1.63715415019763 0.347347292697796 0.635405995779934 GO:0042171 lysophosphatidic acid acyltransferase activity 2/990 23/18639 0.0869565217391304 1.63715415019763 0.347347292697796 0.635405995779934 GO:0044013 histone H2B acetyltransferase activity 2/990 23/18639 0.0869565217391304 1.63715415019763 0.347347292697796 0.635405995779934 GO:0070577 lysine-acetylated histone binding 2/990 23/18639 0.0869565217391304 1.63715415019763 0.347347292697796 0.635405995779934 GO:0071617 lysophospholipid acyltransferase activity 2/990 23/18639 0.0869565217391304 1.63715415019763 0.347347292697796 0.635405995779934 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/990 23/18639 0.0869565217391304 1.63715415019763 0.347347292697796 0.635405995779934 GO:0035064 methylated histone binding 5/990 74/18639 0.0675675675675676 1.27211302211302 0.357107506828311 0.647985149677909 GO:0048029 monosaccharide binding 5/990 74/18639 0.0675675675675676 1.27211302211302 0.357107506828311 0.647985149677909 GO:0004532 RNA exonuclease activity 3/990 40/18639 0.075 1.41204545454545 0.357888122253774 0.647985149677909 GO:0061791 GTPase motor activity 3/990 40/18639 0.075 1.41204545454545 0.357888122253774 0.647985149677909 GO:0071949 FAD binding 3/990 40/18639 0.075 1.41204545454545 0.357888122253774 0.647985149677909 GO:1990606 membrane scission GTPase motor activity 3/990 40/18639 0.075 1.41204545454545 0.357888122253774 0.647985149677909 GO:0004620 phospholipase activity 7/990 109/18639 0.0642201834862385 1.20909090909091 0.358823347105719 0.648571671685124 GO:0015295 solute:proton symporter activity 2/990 24/18639 0.0833333333333333 1.56893939393939 0.366890956426067 0.653643337964909 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2/990 24/18639 0.0833333333333333 1.56893939393939 0.366890956426067 0.653643337964909 GO:0030215 semaphorin receptor binding 2/990 24/18639 0.0833333333333333 1.56893939393939 0.366890956426067 0.653643337964909 GO:0043998 histone H2A acetyltransferase activity 2/990 24/18639 0.0833333333333333 1.56893939393939 0.366890956426067 0.653643337964909 GO:0050431 transforming growth factor beta binding 2/990 24/18639 0.0833333333333333 1.56893939393939 0.366890956426067 0.653643337964909 GO:0060229 lipase activator activity 2/990 24/18639 0.0833333333333333 1.56893939393939 0.366890956426067 0.653643337964909 GO:0140033 acetylation-dependent protein binding 2/990 24/18639 0.0833333333333333 1.56893939393939 0.366890956426067 0.653643337964909 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 11/990 181/18639 0.0607734806629834 1.14419889502762 0.367120663275909 0.653643337964909 GO:0004222 metalloendopeptidase activity 7/990 110/18639 0.0636363636363636 1.19809917355372 0.367588794506469 0.653643337964909 GO:0019003 GDP binding 5/990 75/18639 0.0666666666666667 1.25515151515152 0.367789889505232 0.653643337964909 GO:0042287 MHC protein binding 3/990 41/18639 0.0731707317073171 1.37760532150776 0.372595285432255 0.658872663072705 GO:0061650 ubiquitin-like protein conjugating enzyme activity 3/990 41/18639 0.0731707317073171 1.37760532150776 0.372595285432255 0.658872663072705 GO:0140828 metal cation:monoatomic cation antiporter activity 3/990 41/18639 0.0731707317073171 1.37760532150776 0.372595285432255 0.658872663072705 GO:0140713 histone chaperone activity 10/990 164/18639 0.0609756097560976 1.1480044345898 0.37325591612429 0.658942640612099 GO:1902936 phosphatidylinositol bisphosphate binding 7/990 111/18639 0.0630630630630631 1.18730548730549 0.376368088196969 0.663333125543162 GO:0140034 methylation-dependent protein binding 5/990 76/18639 0.0657894736842105 1.23863636363636 0.378475360081949 0.665940890625121 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 4/990 59/18639 0.0677966101694915 1.27642526964561 0.383507572683894 0.671335828321696 GO:0036002 pre-mRNA binding 4/990 59/18639 0.0677966101694915 1.27642526964561 0.383507572683894 0.671335828321696 GO:0003707 nuclear steroid receptor activity 2/990 25/18639 0.08 1.50618181818182 0.386201955860644 0.671335828321696 GO:0005537 D-mannose binding 2/990 25/18639 0.08 1.50618181818182 0.386201955860644 0.671335828321696 GO:0008139 nuclear localization sequence binding 2/990 25/18639 0.08 1.50618181818182 0.386201955860644 0.671335828321696 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2/990 25/18639 0.08 1.50618181818182 0.386201955860644 0.671335828321696 GO:0004402 histone acetyltransferase activity 3/990 42/18639 0.0714285714285714 1.34480519480519 0.387236123405163 0.671335828321696 GO:0043175 RNA polymerase core enzyme binding 3/990 42/18639 0.0714285714285714 1.34480519480519 0.387236123405163 0.671335828321696 GO:0048487 beta-tubulin binding 3/990 42/18639 0.0714285714285714 1.34480519480519 0.387236123405163 0.671335828321696 GO:0015631 tubulin binding 22/990 385/18639 0.0571428571428571 1.07584415584416 0.392760835933089 0.679803012928234 GO:0004714 transmembrane receptor protein tyrosine kinase activity 4/990 60/18639 0.0666666666666667 1.25515151515152 0.395703895840842 0.683781487764061 GO:0019199 transmembrane receptor protein kinase activity 5/990 78/18639 0.0641025641025641 1.20687645687646 0.399823991536596 0.688803843897806 GO:0048156 tau protein binding 3/990 43/18639 0.0697674418604651 1.31353065539112 0.401793117250302 0.688803843897806 GO:0005227 calcium-activated cation channel activity 2/990 26/18639 0.0769230769230769 1.44825174825175 0.405249876558431 0.688803843897806 GO:0015216 purine nucleotide transmembrane transporter activity 2/990 26/18639 0.0769230769230769 1.44825174825175 0.405249876558431 0.688803843897806 GO:0034237 protein kinase A regulatory subunit binding 2/990 26/18639 0.0769230769230769 1.44825174825175 0.405249876558431 0.688803843897806 GO:0050681 nuclear androgen receptor binding 2/990 26/18639 0.0769230769230769 1.44825174825175 0.405249876558431 0.688803843897806 GO:0051139 metal cation:proton antiporter activity 2/990 26/18639 0.0769230769230769 1.44825174825175 0.405249876558431 0.688803843897806 GO:0000510 H3-H4 histone complex chaperone activity 9/990 151/18639 0.0596026490066225 1.12215532811559 0.410307307111782 0.688803843897806 GO:0140584 chromatin extrusion motor activity 9/990 151/18639 0.0596026490066225 1.12215532811559 0.410307307111782 0.688803843897806 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 9/990 151/18639 0.0596026490066225 1.12215532811559 0.410307307111782 0.688803843897806 GO:0140849 ATP-dependent H2AZ histone chaperone activity 9/990 151/18639 0.0596026490066225 1.12215532811559 0.410307307111782 0.688803843897806 GO:0030547 signaling receptor inhibitor activity 3/990 44/18639 0.0681818181818182 1.28367768595041 0.416249893292644 0.688803843897806 GO:0015616 DNA translocase activity 9/990 152/18639 0.0592105263157895 1.11477272727273 0.417956613557868 0.688803843897806 GO:0140674 ATP-dependent histone chaperone activity 9/990 152/18639 0.0592105263157895 1.11477272727273 0.417956613557868 0.688803843897806 GO:0003796 lysozyme activity 1/990 10/18639 0.1 1.88272727272727 0.420683214746256 0.688803843897806 GO:0004382 GDP phosphatase activity 1/990 10/18639 0.1 1.88272727272727 0.420683214746256 0.688803843897806 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/990 10/18639 0.1 1.88272727272727 0.420683214746256 0.688803843897806 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/990 10/18639 0.1 1.88272727272727 0.420683214746256 0.688803843897806 GO:0005131 growth hormone receptor binding 1/990 10/18639 0.1 1.88272727272727 0.420683214746256 0.688803843897806 GO:0005381 iron ion transmembrane transporter activity 1/990 10/18639 0.1 1.88272727272727 0.420683214746256 0.688803843897806 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/990 10/18639 0.1 1.88272727272727 0.420683214746256 0.688803843897806 GO:0015643 toxic substance binding 1/990 10/18639 0.1 1.88272727272727 0.420683214746256 0.688803843897806 GO:0031434 mitogen-activated protein kinase kinase binding 1/990 10/18639 0.1 1.88272727272727 0.420683214746256 0.688803843897806 GO:0035256 G protein-coupled glutamate receptor binding 1/990 10/18639 0.1 1.88272727272727 0.420683214746256 0.688803843897806 GO:0042975 peroxisome proliferator activated receptor binding 1/990 10/18639 0.1 1.88272727272727 0.420683214746256 0.688803843897806 GO:0043208 glycosphingolipid binding 1/990 10/18639 0.1 1.88272727272727 0.420683214746256 0.688803843897806 GO:0045322 unmethylated CpG binding 1/990 10/18639 0.1 1.88272727272727 0.420683214746256 0.688803843897806 GO:0050308 sugar-phosphatase activity 1/990 10/18639 0.1 1.88272727272727 0.420683214746256 0.688803843897806 GO:0071723 lipopeptide binding 1/990 10/18639 0.1 1.88272727272727 0.420683214746256 0.688803843897806 GO:0098505 G-rich strand telomeric DNA binding 1/990 10/18639 0.1 1.88272727272727 0.420683214746256 0.688803843897806 GO:0099122 RNA polymerase II C-terminal domain binding 1/990 10/18639 0.1 1.88272727272727 0.420683214746256 0.688803843897806 GO:0140940 histone H2A methyltransferase activity 1/990 10/18639 0.1 1.88272727272727 0.420683214746256 0.688803843897806 GO:0140999 histone H3K4 trimethyltransferase activity 1/990 10/18639 0.1 1.88272727272727 0.420683214746256 0.688803843897806 GO:1990259 histone H2AQ104 methyltransferase activity 1/990 10/18639 0.1 1.88272727272727 0.420683214746256 0.688803843897806 GO:0005385 zinc ion transmembrane transporter activity 2/990 27/18639 0.0740740740740741 1.39461279461279 0.424008184536211 0.689988778823497 GO:0008320 protein transmembrane transporter activity 2/990 27/18639 0.0740740740740741 1.39461279461279 0.424008184536211 0.689988778823497 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 2/990 27/18639 0.0740740740740741 1.39461279461279 0.424008184536211 0.689988778823497 GO:0035255 ionotropic glutamate receptor binding 2/990 27/18639 0.0740740740740741 1.39461279461279 0.424008184536211 0.689988778823497 GO:0046915 transition metal ion transmembrane transporter activity 3/990 45/18639 0.0666666666666667 1.25515151515152 0.430591198754119 0.698547711270376 GO:0051539 4 iron, 4 sulfur cluster binding 3/990 45/18639 0.0666666666666667 1.25515151515152 0.430591198754119 0.698547711270376 GO:0019789 SUMO transferase activity 2/990 28/18639 0.0714285714285714 1.34480519480519 0.442453900564355 0.698547711270376 GO:0036408 histone H3K14 acetyltransferase activity 2/990 28/18639 0.0714285714285714 1.34480519480519 0.442453900564355 0.698547711270376 GO:0045499 chemorepellent activity 2/990 28/18639 0.0714285714285714 1.34480519480519 0.442453900564355 0.698547711270376 GO:0046966 nuclear thyroid hormone receptor binding 2/990 28/18639 0.0714285714285714 1.34480519480519 0.442453900564355 0.698547711270376 GO:0051393 alpha-actinin binding 2/990 28/18639 0.0714285714285714 1.34480519480519 0.442453900564355 0.698547711270376 GO:0030291 protein serine/threonine kinase inhibitor activity 3/990 46/18639 0.0652173913043478 1.22786561264822 0.444802874234216 0.698547711270376 GO:0016757 glycosyltransferase activity 15/990 267/18639 0.0561797752808989 1.05771195097038 0.449403893791651 0.698547711270376 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/990 11/18639 0.0909090909090909 1.71157024793388 0.45146981721559 0.698547711270376 GO:0000099 sulfur amino acid transmembrane transporter activity 1/990 11/18639 0.0909090909090909 1.71157024793388 0.45146981721559 0.698547711270376 GO:0001851 complement component C3b binding 1/990 11/18639 0.0909090909090909 1.71157024793388 0.45146981721559 0.698547711270376 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/990 11/18639 0.0909090909090909 1.71157024793388 0.45146981721559 0.698547711270376 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/990 11/18639 0.0909090909090909 1.71157024793388 0.45146981721559 0.698547711270376 GO:0019203 carbohydrate phosphatase activity 1/990 11/18639 0.0909090909090909 1.71157024793388 0.45146981721559 0.698547711270376 GO:0019206 nucleoside kinase activity 1/990 11/18639 0.0909090909090909 1.71157024793388 0.45146981721559 0.698547711270376 GO:0019215 intermediate filament binding 1/990 11/18639 0.0909090909090909 1.71157024793388 0.45146981721559 0.698547711270376 GO:0019864 IgG binding 1/990 11/18639 0.0909090909090909 1.71157024793388 0.45146981721559 0.698547711270376 GO:0031731 CCR6 chemokine receptor binding 1/990 11/18639 0.0909090909090909 1.71157024793388 0.45146981721559 0.698547711270376 GO:0032050 clathrin heavy chain binding 1/990 11/18639 0.0909090909090909 1.71157024793388 0.45146981721559 0.698547711270376 GO:0034056 estrogen response element binding 1/990 11/18639 0.0909090909090909 1.71157024793388 0.45146981721559 0.698547711270376 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/990 11/18639 0.0909090909090909 1.71157024793388 0.45146981721559 0.698547711270376 GO:0035252 UDP-xylosyltransferase activity 1/990 11/18639 0.0909090909090909 1.71157024793388 0.45146981721559 0.698547711270376 GO:0042285 xylosyltransferase activity 1/990 11/18639 0.0909090909090909 1.71157024793388 0.45146981721559 0.698547711270376 GO:0045294 alpha-catenin binding 1/990 11/18639 0.0909090909090909 1.71157024793388 0.45146981721559 0.698547711270376 GO:0047676 arachidonate-CoA ligase activity 1/990 11/18639 0.0909090909090909 1.71157024793388 0.45146981721559 0.698547711270376 GO:0048185 activin binding 1/990 11/18639 0.0909090909090909 1.71157024793388 0.45146981721559 0.698547711270376 GO:0050998 nitric-oxide synthase binding 1/990 11/18639 0.0909090909090909 1.71157024793388 0.45146981721559 0.698547711270376 GO:0070697 activin receptor binding 1/990 11/18639 0.0909090909090909 1.71157024793388 0.45146981721559 0.698547711270376 GO:0140031 phosphorylation-dependent protein binding 1/990 11/18639 0.0909090909090909 1.71157024793388 0.45146981721559 0.698547711270376 GO:0140537 transcription regulator activator activity 1/990 11/18639 0.0909090909090909 1.71157024793388 0.45146981721559 0.698547711270376 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/990 11/18639 0.0909090909090909 1.71157024793388 0.45146981721559 0.698547711270376 GO:0180030 inositol phosphate kinase activity 1/990 11/18639 0.0909090909090909 1.71157024793388 0.45146981721559 0.698547711270376 GO:0061733 protein-lysine-acetyltransferase activity 3/990 47/18639 0.0638297872340425 1.20174081237911 0.458871823559132 0.698547711270376 GO:0061749 forked DNA-dependent helicase activity 3/990 47/18639 0.0638297872340425 1.20174081237911 0.458871823559132 0.698547711270376 GO:1990518 single-stranded 3'-5' DNA helicase activity 3/990 47/18639 0.0638297872340425 1.20174081237911 0.458871823559132 0.698547711270376 GO:0005416 amino acid:monoatomic cation symporter activity 2/990 29/18639 0.0689655172413793 1.29843260188088 0.46056729805686 0.698547711270376 GO:0043236 laminin binding 2/990 29/18639 0.0689655172413793 1.29843260188088 0.46056729805686 0.698547711270376 GO:0051861 glycolipid binding 2/990 29/18639 0.0689655172413793 1.29843260188088 0.46056729805686 0.698547711270376 GO:0099604 ligand-gated calcium channel activity 2/990 29/18639 0.0689655172413793 1.29843260188088 0.46056729805686 0.698547711270376 GO:0008514 organic anion transmembrane transporter activity 15/990 269/18639 0.0557620817843866 1.04984792159513 0.461035321457515 0.698547711270376 GO:0140658 ATP-dependent chromatin remodeler activity 9/990 158/18639 0.0569620253164557 1.07243958573072 0.463682811743513 0.698547711270376 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 7/990 122/18639 0.0573770491803279 1.08025335320417 0.472601780474644 0.698547711270376 GO:0009378 four-way junction helicase activity 3/990 48/18639 0.0625 1.17670454545455 0.472785981482088 0.698547711270376 GO:0036121 double-stranded DNA helicase activity 3/990 48/18639 0.0625 1.17670454545455 0.472785981482088 0.698547711270376 GO:0043138 3'-5' DNA helicase activity 3/990 48/18639 0.0625 1.17670454545455 0.472785981482088 0.698547711270376 GO:0001965 G-protein alpha-subunit binding 2/990 30/18639 0.0666666666666667 1.25515151515152 0.478331622973907 0.698547711270376 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 2/990 30/18639 0.0666666666666667 1.25515151515152 0.478331622973907 0.698547711270376 GO:0022839 monoatomic ion-gated channel activity 2/990 30/18639 0.0666666666666667 1.25515151515152 0.478331622973907 0.698547711270376 GO:0043995 histone H4K5 acetyltransferase activity 2/990 30/18639 0.0666666666666667 1.25515151515152 0.478331622973907 0.698547711270376 GO:0043996 histone H4K8 acetyltransferase activity 2/990 30/18639 0.0666666666666667 1.25515151515152 0.478331622973907 0.698547711270376 GO:0043997 histone H4K12 acetyltransferase activity 2/990 30/18639 0.0666666666666667 1.25515151515152 0.478331622973907 0.698547711270376 GO:0003689 DNA clamp loader activity 9/990 160/18639 0.05625 1.05903409090909 0.478796233978934 0.698547711270376 GO:0000340 RNA 7-methylguanosine cap binding 1/990 12/18639 0.0833333333333333 1.56893939393939 0.480621893711003 0.698547711270376 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/990 12/18639 0.0833333333333333 1.56893939393939 0.480621893711003 0.698547711270376 GO:0005165 neurotrophin receptor binding 1/990 12/18639 0.0833333333333333 1.56893939393939 0.480621893711003 0.698547711270376 GO:0008603 cAMP-dependent protein kinase regulator activity 1/990 12/18639 0.0833333333333333 1.56893939393939 0.480621893711003 0.698547711270376 GO:0015132 prostaglandin transmembrane transporter activity 1/990 12/18639 0.0833333333333333 1.56893939393939 0.480621893711003 0.698547711270376 GO:0015368 calcium:monoatomic cation antiporter activity 1/990 12/18639 0.0833333333333333 1.56893939393939 0.480621893711003 0.698547711270376 GO:0016208 AMP binding 1/990 12/18639 0.0833333333333333 1.56893939393939 0.480621893711003 0.698547711270376 GO:0016840 carbon-nitrogen lyase activity 1/990 12/18639 0.0833333333333333 1.56893939393939 0.480621893711003 0.698547711270376 GO:0017166 vinculin binding 1/990 12/18639 0.0833333333333333 1.56893939393939 0.480621893711003 0.698547711270376 GO:0031543 peptidyl-proline dioxygenase activity 1/990 12/18639 0.0833333333333333 1.56893939393939 0.480621893711003 0.698547711270376 GO:0036009 protein-glutamine N-methyltransferase activity 1/990 12/18639 0.0833333333333333 1.56893939393939 0.480621893711003 0.698547711270376 GO:0042301 phosphate ion binding 1/990 12/18639 0.0833333333333333 1.56893939393939 0.480621893711003 0.698547711270376 GO:0043047 single-stranded telomeric DNA binding 1/990 12/18639 0.0833333333333333 1.56893939393939 0.480621893711003 0.698547711270376 GO:0045295 gamma-catenin binding 1/990 12/18639 0.0833333333333333 1.56893939393939 0.480621893711003 0.698547711270376 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/990 12/18639 0.0833333333333333 1.56893939393939 0.480621893711003 0.698547711270376 GO:0070008 serine-type exopeptidase activity 1/990 12/18639 0.0833333333333333 1.56893939393939 0.480621893711003 0.698547711270376 GO:0097677 STAT family protein binding 1/990 12/18639 0.0833333333333333 1.56893939393939 0.480621893711003 0.698547711270376 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/990 12/18639 0.0833333333333333 1.56893939393939 0.480621893711003 0.698547711270376 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/990 12/18639 0.0833333333333333 1.56893939393939 0.480621893711003 0.698547711270376 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/990 12/18639 0.0833333333333333 1.56893939393939 0.480621893711003 0.698547711270376 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/990 12/18639 0.0833333333333333 1.56893939393939 0.480621893711003 0.698547711270376 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/990 12/18639 0.0833333333333333 1.56893939393939 0.480621893711003 0.698547711270376 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/990 12/18639 0.0833333333333333 1.56893939393939 0.480621893711003 0.698547711270376 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/990 12/18639 0.0833333333333333 1.56893939393939 0.480621893711003 0.698547711270376 GO:1990459 transferrin receptor binding 1/990 12/18639 0.0833333333333333 1.56893939393939 0.480621893711003 0.698547711270376 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 5/990 86/18639 0.0581395348837209 1.0946088794926 0.483866157557057 0.701341520721362 GO:0050660 flavin adenine dinucleotide binding 5/990 86/18639 0.0581395348837209 1.0946088794926 0.483866157557057 0.701341520721362 GO:0004866 endopeptidase inhibitor activity 9/990 161/18639 0.0559006211180124 1.05245623941276 0.486317386901517 0.703932806961132 GO:0008083 growth factor activity 9/990 162/18639 0.0555555555555556 1.0459595959596 0.493811625109723 0.712699914829309 GO:0005164 tumor necrosis factor receptor binding 2/990 31/18639 0.0645161290322581 1.21466275659824 0.495732834254505 0.712699914829309 GO:0005452 solute:inorganic anion antiporter activity 2/990 31/18639 0.0645161290322581 1.21466275659824 0.495732834254505 0.712699914829309 GO:0016411 acylglycerol O-acyltransferase activity 2/990 31/18639 0.0645161290322581 1.21466275659824 0.495732834254505 0.712699914829309 GO:0047499 calcium-independent phospholipase A2 activity 2/990 31/18639 0.0645161290322581 1.21466275659824 0.495732834254505 0.712699914829309 GO:0000149 SNARE binding 6/990 106/18639 0.0566037735849057 1.06569468267581 0.496437596493195 0.712747347603897 GO:0015605 organophosphate ester transmembrane transporter activity 3/990 50/18639 0.06 1.12963636363636 0.500106611342287 0.715156414092945 GO:0008017 microtubule binding 15/990 276/18639 0.0543478260869565 1.02322134387352 0.501484699044497 0.715156414092945 GO:0002039 p53 binding 4/990 69/18639 0.0579710144927536 1.09143610013175 0.502553278303876 0.715156414092945 GO:0008080 N-acetyltransferase activity 4/990 69/18639 0.0579710144927536 1.09143610013175 0.502553278303876 0.715156414092945 GO:0008253 5'-nucleotidase activity 1/990 13/18639 0.0769230769230769 1.44825174825175 0.508226141589143 0.715156414092945 GO:0035673 oligopeptide transmembrane transporter activity 1/990 13/18639 0.0769230769230769 1.44825174825175 0.508226141589143 0.715156414092945 GO:0039706 co-receptor binding 1/990 13/18639 0.0769230769230769 1.44825174825175 0.508226141589143 0.715156414092945 GO:0046975 histone H3K36 methyltransferase activity 1/990 13/18639 0.0769230769230769 1.44825174825175 0.508226141589143 0.715156414092945 GO:0061459 L-arginine transmembrane transporter activity 1/990 13/18639 0.0769230769230769 1.44825174825175 0.508226141589143 0.715156414092945 GO:0070123 transforming growth factor beta receptor activity, type III 1/990 13/18639 0.0769230769230769 1.44825174825175 0.508226141589143 0.715156414092945 GO:0071714 icosanoid transmembrane transporter activity 1/990 13/18639 0.0769230769230769 1.44825174825175 0.508226141589143 0.715156414092945 GO:0071837 HMG box domain binding 1/990 13/18639 0.0769230769230769 1.44825174825175 0.508226141589143 0.715156414092945 GO:0089720 caspase binding 1/990 13/18639 0.0769230769230769 1.44825174825175 0.508226141589143 0.715156414092945 GO:0140333 glycerophospholipid flippase activity 1/990 13/18639 0.0769230769230769 1.44825174825175 0.508226141589143 0.715156414092945 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/990 13/18639 0.0769230769230769 1.44825174825175 0.508226141589143 0.715156414092945 GO:0015106 bicarbonate transmembrane transporter activity 2/990 32/18639 0.0625 1.17670454545455 0.51275936339195 0.715922360657256 GO:0022884 macromolecule transmembrane transporter activity 2/990 32/18639 0.0625 1.17670454545455 0.51275936339195 0.715922360657256 GO:0030515 snoRNA binding 2/990 32/18639 0.0625 1.17670454545455 0.51275936339195 0.715922360657256 GO:0047498 calcium-dependent phospholipase A2 activity 2/990 32/18639 0.0625 1.17670454545455 0.51275936339195 0.715922360657256 GO:0005048 signal sequence binding 3/990 51/18639 0.0588235294117647 1.10748663101604 0.513493794967174 0.715922360657256 GO:0016597 amino acid binding 3/990 51/18639 0.0588235294117647 1.10748663101604 0.513493794967174 0.715922360657256 GO:0016830 carbon-carbon lyase activity 3/990 51/18639 0.0588235294117647 1.10748663101604 0.513493794967174 0.715922360657256 GO:0015293 symporter activity 8/990 146/18639 0.0547945205479452 1.03163138231631 0.515673994313732 0.718018514392217 GO:0008237 metallopeptidase activity 10/990 184/18639 0.0543478260869565 1.02322134387352 0.516542455635534 0.718285118518089 GO:0140311 protein sequestering activity 2/990 33/18639 0.0606060606060606 1.14104683195592 0.529401891854054 0.728741527742763 GO:0005161 platelet-derived growth factor receptor binding 1/990 14/18639 0.0714285714285714 1.34480519480519 0.534364664075278 0.728741527742763 GO:0005313 L-glutamate transmembrane transporter activity 1/990 14/18639 0.0714285714285714 1.34480519480519 0.534364664075278 0.728741527742763 GO:0008191 metalloendopeptidase inhibitor activity 1/990 14/18639 0.0714285714285714 1.34480519480519 0.534364664075278 0.728741527742763 GO:0008474 palmitoyl-(protein) hydrolase activity 1/990 14/18639 0.0714285714285714 1.34480519480519 0.534364664075278 0.728741527742763 GO:0008494 translation activator activity 1/990 14/18639 0.0714285714285714 1.34480519480519 0.534364664075278 0.728741527742763 GO:0015386 potassium:proton antiporter activity 1/990 14/18639 0.0714285714285714 1.34480519480519 0.534364664075278 0.728741527742763 GO:0016530 metallochaperone activity 1/990 14/18639 0.0714285714285714 1.34480519480519 0.534364664075278 0.728741527742763 GO:0019763 immunoglobulin receptor activity 1/990 14/18639 0.0714285714285714 1.34480519480519 0.534364664075278 0.728741527742763 GO:0034236 protein kinase A catalytic subunit binding 1/990 14/18639 0.0714285714285714 1.34480519480519 0.534364664075278 0.728741527742763 GO:0042043 neurexin family protein binding 1/990 14/18639 0.0714285714285714 1.34480519480519 0.534364664075278 0.728741527742763 GO:0061783 peptidoglycan muralytic activity 1/990 14/18639 0.0714285714285714 1.34480519480519 0.534364664075278 0.728741527742763 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/990 14/18639 0.0714285714285714 1.34480519480519 0.534364664075278 0.728741527742763 GO:0098599 palmitoyl hydrolase activity 1/990 14/18639 0.0714285714285714 1.34480519480519 0.534364664075278 0.728741527742763 GO:0098847 sequence-specific single stranded DNA binding 1/990 14/18639 0.0714285714285714 1.34480519480519 0.534364664075278 0.728741527742763 GO:0016251 RNA polymerase II general transcription initiation factor activity 3/990 53/18639 0.0566037735849057 1.06569468267581 0.539680395570819 0.732961001137683 GO:0034212 protein N-acetyltransferase activity 3/990 53/18639 0.0566037735849057 1.06569468267581 0.539680395570819 0.732961001137683 GO:0051018 protein kinase A binding 3/990 53/18639 0.0566037735849057 1.06569468267581 0.539680395570819 0.732961001137683 GO:0016298 lipase activity 7/990 130/18639 0.0538461538461538 1.01377622377622 0.540221963138235 0.732961001137683 GO:0046943 carboxylic acid transmembrane transporter activity 10/990 188/18639 0.0531914893617021 1.00145067698259 0.544247405093629 0.734692876886921 GO:0030414 peptidase inhibitor activity 9/990 169/18639 0.0532544378698225 1.00263582571275 0.545328944822467 0.734692876886921 GO:0015020 glucuronosyltransferase activity 2/990 34/18639 0.0588235294117647 1.10748663101604 0.545653145133736 0.734692876886921 GO:0016831 carboxy-lyase activity 2/990 34/18639 0.0588235294117647 1.10748663101604 0.545653145133736 0.734692876886921 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 2/990 34/18639 0.0588235294117647 1.10748663101604 0.545653145133736 0.734692876886921 GO:0019825 oxygen binding 2/990 34/18639 0.0588235294117647 1.10748663101604 0.545653145133736 0.734692876886921 GO:0004521 RNA endonuclease activity 4/990 73/18639 0.0547945205479452 1.03163138231631 0.547369696508053 0.735505768066704 GO:0005342 organic acid transmembrane transporter activity 10/990 189/18639 0.0529100529100529 0.996151996151996 0.551083281779211 0.735505768066704 GO:0017069 snRNA binding 3/990 54/18639 0.0555555555555556 1.0459595959596 0.552465740695534 0.735505768066704 GO:0051287 NAD binding 3/990 54/18639 0.0555555555555556 1.0459595959596 0.552465740695534 0.735505768066704 GO:0004089 carbonate dehydratase activity 1/990 15/18639 0.0666666666666667 1.25515151515152 0.559115213474767 0.735505768066704 GO:0004467 long-chain fatty acid-CoA ligase activity 1/990 15/18639 0.0666666666666667 1.25515151515152 0.559115213474767 0.735505768066704 GO:0008252 nucleotidase activity 1/990 15/18639 0.0666666666666667 1.25515151515152 0.559115213474767 0.735505768066704 GO:0015250 water channel activity 1/990 15/18639 0.0666666666666667 1.25515151515152 0.559115213474767 0.735505768066704 GO:0015929 hexosaminidase activity 1/990 15/18639 0.0666666666666667 1.25515151515152 0.559115213474767 0.735505768066704 GO:0017081 chloride channel regulator activity 1/990 15/18639 0.0666666666666667 1.25515151515152 0.559115213474767 0.735505768066704 GO:0030553 cGMP binding 1/990 15/18639 0.0666666666666667 1.25515151515152 0.559115213474767 0.735505768066704 GO:0033130 acetylcholine receptor binding 1/990 15/18639 0.0666666666666667 1.25515151515152 0.559115213474767 0.735505768066704 GO:0034483 heparan sulfate sulfotransferase activity 1/990 15/18639 0.0666666666666667 1.25515151515152 0.559115213474767 0.735505768066704 GO:0047372 monoacylglycerol lipase activity 1/990 15/18639 0.0666666666666667 1.25515151515152 0.559115213474767 0.735505768066704 GO:0051371 muscle alpha-actinin binding 1/990 15/18639 0.0666666666666667 1.25515151515152 0.559115213474767 0.735505768066704 GO:0141050 histone H3K deacetylase activity 1/990 15/18639 0.0666666666666667 1.25515151515152 0.559115213474767 0.735505768066704 GO:0141051 histone H4K deacetylase activity 1/990 15/18639 0.0666666666666667 1.25515151515152 0.559115213474767 0.735505768066704 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 12/990 229/18639 0.0524017467248908 0.98658197697499 0.561325435087233 0.735505768066704 GO:0000175 3'-5'-RNA exonuclease activity 2/990 35/18639 0.0571428571428571 1.07584415584416 0.561507702294091 0.735505768066704 GO:0004623 phospholipase A2 activity 2/990 35/18639 0.0571428571428571 1.07584415584416 0.561507702294091 0.735505768066704 GO:0005343 organic acid:sodium symporter activity 2/990 35/18639 0.0571428571428571 1.07584415584416 0.561507702294091 0.735505768066704 GO:0043015 gamma-tubulin binding 2/990 35/18639 0.0571428571428571 1.07584415584416 0.561507702294091 0.735505768066704 GO:0016410 N-acyltransferase activity 5/990 94/18639 0.0531914893617021 1.00145067698259 0.563437653285048 0.737123736295235 GO:0140104 molecular carrier activity 13/990 249/18639 0.0522088353413655 0.982949981745162 0.565957298635306 0.739508243660172 GO:0005506 iron ion binding 8/990 154/18639 0.051948051948052 0.978040141676505 0.576876828720723 0.744683202691778 GO:0005484 SNAP receptor activity 2/990 36/18639 0.0555555555555556 1.0459595959596 0.576961819945558 0.744683202691778 GO:0045505 dynein intermediate chain binding 2/990 36/18639 0.0555555555555556 1.0459595959596 0.576961819945558 0.744683202691778 GO:0030170 pyridoxal phosphate binding 3/990 56/18639 0.0535714285714286 1.0086038961039 0.577391214858766 0.744683202691778 GO:0170055 lipid transmembrane transporter activity 3/990 56/18639 0.0535714285714286 1.0086038961039 0.577391214858766 0.744683202691778 GO:0004175 endopeptidase activity 21/990 405/18639 0.0518518518518519 0.976228956228956 0.577624174537484 0.744683202691778 GO:0016407 acetyltransferase activity 5/990 96/18639 0.0520833333333333 0.980587121212121 0.582347680505592 0.744683202691778 GO:0003688 DNA replication origin binding 1/990 16/18639 0.0625 1.17670454545455 0.582551421521372 0.744683202691778 GO:0005024 transforming growth factor beta receptor activity 1/990 16/18639 0.0625 1.17670454545455 0.582551421521372 0.744683202691778 GO:0008142 oxysterol binding 1/990 16/18639 0.0625 1.17670454545455 0.582551421521372 0.744683202691778 GO:0015385 sodium:proton antiporter activity 1/990 16/18639 0.0625 1.17670454545455 0.582551421521372 0.744683202691778 GO:0015562 efflux transmembrane transporter activity 1/990 16/18639 0.0625 1.17670454545455 0.582551421521372 0.744683202691778 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/990 16/18639 0.0625 1.17670454545455 0.582551421521372 0.744683202691778 GO:0022858 alanine transmembrane transporter activity 1/990 16/18639 0.0625 1.17670454545455 0.582551421521372 0.744683202691778 GO:0043023 ribosomal large subunit binding 1/990 16/18639 0.0625 1.17670454545455 0.582551421521372 0.744683202691778 GO:0070411 I-SMAD binding 1/990 16/18639 0.0625 1.17670454545455 0.582551421521372 0.744683202691778 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/990 16/18639 0.0625 1.17670454545455 0.582551421521372 0.744683202691778 GO:0140327 flippase activity 1/990 16/18639 0.0625 1.17670454545455 0.582551421521372 0.744683202691778 GO:0004601 peroxidase activity 3/990 57/18639 0.0526315789473684 0.990909090909091 0.58952181453142 0.750879526071833 GO:0015932 nucleobase-containing compound transmembrane transporter activity 3/990 57/18639 0.0526315789473684 0.990909090909091 0.58952181453142 0.750879526071833 GO:0070279 vitamin B6 binding 3/990 57/18639 0.0526315789473684 0.990909090909091 0.58952181453142 0.750879526071833 GO:0070001 aspartic-type peptidase activity 2/990 37/18639 0.0540540540540541 1.01769041769042 0.592013269661811 0.753148775912688 GO:0017116 single-stranded DNA helicase activity 3/990 58/18639 0.0517241379310345 0.973824451410658 0.601425768867191 0.762939764104825 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/990 17/18639 0.0588235294117647 1.10748663101604 0.604743017542091 0.762939764104825 GO:0008569 minus-end-directed microtubule motor activity 1/990 17/18639 0.0588235294117647 1.10748663101604 0.604743017542091 0.762939764104825 GO:0009881 photoreceptor activity 1/990 17/18639 0.0588235294117647 1.10748663101604 0.604743017542091 0.762939764104825 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/990 17/18639 0.0588235294117647 1.10748663101604 0.604743017542091 0.762939764104825 GO:0016805 dipeptidase activity 1/990 17/18639 0.0588235294117647 1.10748663101604 0.604743017542091 0.762939764104825 GO:0017110 nucleoside diphosphate phosphatase activity 1/990 17/18639 0.0588235294117647 1.10748663101604 0.604743017542091 0.762939764104825 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 2/990 38/18639 0.0526315789473684 0.990909090909091 0.606661187905634 0.764450736778952 GO:0015370 solute:sodium symporter activity 4/990 79/18639 0.0506329113924051 0.953279631760644 0.610388914286208 0.768235632334124 GO:0031593 polyubiquitin modification-dependent protein binding 3/990 59/18639 0.0508474576271186 0.957318952234206 0.613099957948439 0.770733477942291 GO:0000217 DNA secondary structure binding 2/990 39/18639 0.0512820512820513 0.965501165501165 0.620905937596629 0.77111167621637 GO:0016776 phosphotransferase activity, phosphate group as acceptor 2/990 39/18639 0.0512820512820513 0.965501165501165 0.620905937596629 0.77111167621637 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 3/990 60/18639 0.05 0.941363636363636 0.624541855954102 0.77111167621637 GO:0000400 four-way junction DNA binding 1/990 18/18639 0.0555555555555556 1.0459595959596 0.625756035082276 0.77111167621637 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/990 18/18639 0.0555555555555556 1.0459595959596 0.625756035082276 0.77111167621637 GO:0005372 water transmembrane transporter activity 1/990 18/18639 0.0555555555555556 1.0459595959596 0.625756035082276 0.77111167621637 GO:0015280 ligand-gated sodium channel activity 1/990 18/18639 0.0555555555555556 1.0459595959596 0.625756035082276 0.77111167621637 GO:0017075 syntaxin-1 binding 1/990 18/18639 0.0555555555555556 1.0459595959596 0.625756035082276 0.77111167621637 GO:0017128 phospholipid scramblase activity 1/990 18/18639 0.0555555555555556 1.0459595959596 0.625756035082276 0.77111167621637 GO:0031690 adrenergic receptor binding 1/990 18/18639 0.0555555555555556 1.0459595959596 0.625756035082276 0.77111167621637 GO:0032393 MHC class I receptor activity 1/990 18/18639 0.0555555555555556 1.0459595959596 0.625756035082276 0.77111167621637 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/990 18/18639 0.0555555555555556 1.0459595959596 0.625756035082276 0.77111167621637 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/990 18/18639 0.0555555555555556 1.0459595959596 0.625756035082276 0.77111167621637 GO:0070064 proline-rich region binding 1/990 18/18639 0.0555555555555556 1.0459595959596 0.625756035082276 0.77111167621637 GO:0070628 proteasome binding 1/990 18/18639 0.0555555555555556 1.0459595959596 0.625756035082276 0.77111167621637 GO:0098641 cadherin binding involved in cell-cell adhesion 1/990 18/18639 0.0555555555555556 1.0459595959596 0.625756035082276 0.77111167621637 GO:0099602 neurotransmitter receptor regulator activity 1/990 18/18639 0.0555555555555556 1.0459595959596 0.625756035082276 0.77111167621637 GO:0004540 RNA nuclease activity 6/990 121/18639 0.0495867768595041 0.933583771600301 0.626688040492208 0.771364281858738 GO:0004177 aminopeptidase activity 2/990 40/18639 0.05 0.941363636363636 0.634748980509411 0.779450690671719 GO:0015026 coreceptor activity 3/990 61/18639 0.0491803278688525 0.925931445603577 0.635749496934498 0.779450690671719 GO:0019905 syntaxin binding 3/990 61/18639 0.0491803278688525 0.925931445603577 0.635749496934498 0.779450690671719 GO:0022804 active transmembrane transporter activity 23/990 457/18639 0.050328227571116 0.947543266361647 0.636196322452129 0.779450690671719 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/990 19/18639 0.0526315789473684 0.990909090909091 0.64565300760086 0.78559385443178 GO:0008301 DNA binding, bending 1/990 19/18639 0.0526315789473684 0.990909090909091 0.64565300760086 0.78559385443178 GO:0008574 plus-end-directed microtubule motor activity 1/990 19/18639 0.0526315789473684 0.990909090909091 0.64565300760086 0.78559385443178 GO:0015245 fatty acid transmembrane transporter activity 1/990 19/18639 0.0526315789473684 0.990909090909091 0.64565300760086 0.78559385443178 GO:0022821 solute:potassium antiporter activity 1/990 19/18639 0.0526315789473684 0.990909090909091 0.64565300760086 0.78559385443178 GO:0046624 sphingolipid transporter activity 1/990 19/18639 0.0526315789473684 0.990909090909091 0.64565300760086 0.78559385443178 GO:0016877 ligase activity, forming carbon-sulfur bonds 2/990 41/18639 0.0487804878048781 0.91840354767184 0.648192759744136 0.786879311314106 GO:0140318 protein transporter activity 2/990 41/18639 0.0487804878048781 0.91840354767184 0.648192759744136 0.786879311314106 GO:0008135 translation factor activity, RNA binding 4/990 83/18639 0.0481927710843374 0.907338444687842 0.649262342124933 0.787276965708062 GO:0008194 UDP-glycosyltransferase activity 7/990 145/18639 0.0482758620689655 0.908902821316614 0.655807875880155 0.794306114507813 GO:0005507 copper ion binding 3/990 63/18639 0.0476190476190476 0.896536796536797 0.657456744350336 0.794489300405132 GO:1901682 sulfur compound transmembrane transporter activity 3/990 63/18639 0.0476190476190476 0.896536796536797 0.657456744350336 0.794489300405132 GO:0180051 translation factor activity 4/990 84/18639 0.0476190476190476 0.896536796536797 0.658567221771861 0.794844685677433 GO:0042056 chemoattractant activity 2/990 42/18639 0.0476190476190476 0.896536796536797 0.661240591561086 0.794844685677433 GO:0000339 RNA cap binding 1/990 20/18639 0.05 0.941363636363636 0.664493153813274 0.794844685677433 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/990 20/18639 0.05 0.941363636363636 0.664493153813274 0.794844685677433 GO:0015095 magnesium ion transmembrane transporter activity 1/990 20/18639 0.05 0.941363636363636 0.664493153813274 0.794844685677433 GO:0031418 L-ascorbic acid binding 1/990 20/18639 0.05 0.941363636363636 0.664493153813274 0.794844685677433 GO:0042288 MHC class I protein binding 1/990 20/18639 0.05 0.941363636363636 0.664493153813274 0.794844685677433 GO:0043024 ribosomal small subunit binding 1/990 20/18639 0.05 0.941363636363636 0.664493153813274 0.794844685677433 GO:0140939 histone H4 methyltransferase activity 1/990 20/18639 0.05 0.941363636363636 0.664493153813274 0.794844685677433 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 8/990 167/18639 0.0479041916167665 0.901905280348394 0.667849112107165 0.79795935579471 GO:0015085 calcium ion transmembrane transporter activity 7/990 147/18639 0.0476190476190476 0.896536796536797 0.66983332834423 0.799429877810155 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/990 43/18639 0.0465116279069767 0.87568710359408 0.673896565917709 0.802998748120652 GO:0005201 extracellular matrix structural constituent 8/990 168/18639 0.0476190476190476 0.896536796536797 0.674337308742225 0.802998748120652 GO:0001846 opsonin binding 1/990 21/18639 0.0476190476190476 0.896536796536797 0.682332553229185 0.807084547353585 GO:0005248 voltage-gated sodium channel activity 1/990 21/18639 0.0476190476190476 0.896536796536797 0.682332553229185 0.807084547353585 GO:0015174 basic amino acid transmembrane transporter activity 1/990 21/18639 0.0476190476190476 0.896536796536797 0.682332553229185 0.807084547353585 GO:0019200 carbohydrate kinase activity 1/990 21/18639 0.0476190476190476 0.896536796536797 0.682332553229185 0.807084547353585 GO:0036122 BMP binding 1/990 21/18639 0.0476190476190476 0.896536796536797 0.682332553229185 0.807084547353585 GO:0051428 peptide hormone receptor binding 1/990 21/18639 0.0476190476190476 0.896536796536797 0.682332553229185 0.807084547353585 GO:0008094 ATP-dependent activity, acting on DNA 10/990 210/18639 0.0476190476190476 0.896536796536797 0.683471921584288 0.807531969711503 GO:0019205 nucleobase-containing compound kinase activity 2/990 44/18639 0.0454545454545455 0.855785123966942 0.686165455090331 0.809812622748433 GO:0046873 metal ion transmembrane transporter activity 22/990 450/18639 0.0488888888888889 0.920444444444444 0.687322623377673 0.810277003781901 GO:0016651 oxidoreductase activity, acting on NAD(P)H 4/990 88/18639 0.0454545454545455 0.855785123966942 0.6940976079035 0.81614630963682 GO:0004407 histone deacetylase activity 1/990 22/18639 0.0454545454545455 0.855785123966942 0.69922431240327 0.81614630963682 GO:0008093 cytoskeletal anchor activity 1/990 22/18639 0.0454545454545455 0.855785123966942 0.69922431240327 0.81614630963682 GO:0015377 chloride:monoatomic cation symporter activity 1/990 22/18639 0.0454545454545455 0.855785123966942 0.69922431240327 0.81614630963682 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/990 22/18639 0.0454545454545455 0.855785123966942 0.69922431240327 0.81614630963682 GO:0033558 protein lysine deacetylase activity 1/990 22/18639 0.0454545454545455 0.855785123966942 0.69922431240327 0.81614630963682 GO:0033691 sialic acid binding 1/990 22/18639 0.0454545454545455 0.855785123966942 0.69922431240327 0.81614630963682 GO:0034062 5'-3' RNA polymerase activity 1/990 22/18639 0.0454545454545455 0.855785123966942 0.69922431240327 0.81614630963682 GO:0097747 RNA polymerase activity 1/990 22/18639 0.0454545454545455 0.855785123966942 0.69922431240327 0.81614630963682 GO:0003777 microtubule motor activity 3/990 68/18639 0.0441176470588235 0.830614973262032 0.707581275530282 0.824087522873358 GO:0140223 general transcription initiation factor activity 3/990 68/18639 0.0441176470588235 0.830614973262032 0.707581275530282 0.824087522873358 GO:0140097 catalytic activity, acting on DNA 16/990 336/18639 0.0476190476190476 0.896536796536797 0.709500786003582 0.825417032839694 GO:0016493 C-C chemokine receptor activity 1/990 23/18639 0.0434782608695652 0.818577075098814 0.715218722389882 0.829341054049907 GO:0016849 phosphorus-oxygen lyase activity 1/990 23/18639 0.0434782608695652 0.818577075098814 0.715218722389882 0.829341054049907 GO:0099186 structural constituent of postsynapse 1/990 23/18639 0.0434782608695652 0.818577075098814 0.715218722389882 0.829341054049907 GO:0043022 ribosome binding 5/990 112/18639 0.0446428571428571 0.840503246753247 0.716067809281588 0.829419154637298 GO:0043495 protein-membrane adaptor activity 2/990 47/18639 0.0425531914893617 0.801160541586074 0.720705856052655 0.832972672409441 GO:0140359 ABC-type transporter activity 2/990 47/18639 0.0425531914893617 0.801160541586074 0.720705856052655 0.832972672409441 GO:0004386 helicase activity 7/990 155/18639 0.0451612903225806 0.850263929618768 0.722294528327353 0.833900429331144 GO:0015297 antiporter activity 6/990 135/18639 0.0444444444444444 0.836767676767677 0.728676804055674 0.84035444467725 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/990 24/18639 0.0416666666666667 0.784469696969697 0.73036340786657 0.841384989952693 GO:0001848 complement binding 1/990 25/18639 0.04 0.753090909090909 0.744703468366817 0.847779377615013 GO:0005251 delayed rectifier potassium channel activity 1/990 25/18639 0.04 0.753090909090909 0.744703468366817 0.847779377615013 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/990 25/18639 0.04 0.753090909090909 0.744703468366817 0.847779377615013 GO:0015645 fatty acid ligase activity 1/990 25/18639 0.04 0.753090909090909 0.744703468366817 0.847779377615013 GO:0015662 P-type ion transporter activity 1/990 25/18639 0.04 0.753090909090909 0.744703468366817 0.847779377615013 GO:0017056 structural constituent of nuclear pore 1/990 25/18639 0.04 0.753090909090909 0.744703468366817 0.847779377615013 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/990 25/18639 0.04 0.753090909090909 0.744703468366817 0.847779377615013 GO:0019707 protein-cysteine S-acyltransferase activity 1/990 25/18639 0.04 0.753090909090909 0.744703468366817 0.847779377615013 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/990 25/18639 0.04 0.753090909090909 0.744703468366817 0.847779377615013 GO:0120515 fatty acid-CoA ligase activity 1/990 25/18639 0.04 0.753090909090909 0.744703468366817 0.847779377615013 GO:0140358 P-type transmembrane transporter activity 1/990 25/18639 0.04 0.753090909090909 0.744703468366817 0.847779377615013 GO:0004867 serine-type endopeptidase inhibitor activity 4/990 95/18639 0.0421052631578947 0.792727272727273 0.749742617150967 0.852601196995902 GO:0015079 potassium ion transmembrane transporter activity 7/990 160/18639 0.04375 0.823693181818182 0.752049694625494 0.85430912847714 GO:0001637 G protein-coupled chemoattractant receptor activity 1/990 26/18639 0.0384615384615385 0.724125874125874 0.758281612039152 0.857899894368497 GO:0004950 chemokine receptor activity 1/990 26/18639 0.0384615384615385 0.724125874125874 0.758281612039152 0.857899894368497 GO:0030507 spectrin binding 1/990 26/18639 0.0384615384615385 0.724125874125874 0.758281612039152 0.857899894368497 GO:0003678 DNA helicase activity 3/990 74/18639 0.0405405405405405 0.763267813267813 0.760062111881609 0.857899894368497 GO:0003684 damaged DNA binding 3/990 74/18639 0.0405405405405405 0.763267813267813 0.760062111881609 0.857899894368497 GO:0031491 nucleosome binding 3/990 74/18639 0.0405405405405405 0.763267813267813 0.760062111881609 0.857899894368497 GO:0008168 methyltransferase activity 9/990 204/18639 0.0441176470588235 0.830614973262032 0.761684284231401 0.858817242900655 GO:0005249 voltage-gated potassium channel activity 4/990 98/18639 0.0408163265306122 0.768460111317254 0.771084008210028 0.865462943726271 GO:0005044 scavenger receptor activity 1/990 27/18639 0.037037037037037 0.697306397306397 0.771138282327727 0.865462943726271 GO:0015252 proton channel activity 1/990 27/18639 0.037037037037037 0.697306397306397 0.771138282327727 0.865462943726271 GO:0016405 CoA-ligase activity 1/990 27/18639 0.037037037037037 0.697306397306397 0.771138282327727 0.865462943726271 GO:0020037 heme binding 6/990 142/18639 0.0422535211267606 0.795518565941101 0.771656875367628 0.865462943726271 GO:0015081 sodium ion transmembrane transporter activity 7/990 164/18639 0.0426829268292683 0.80360310421286 0.774163342827566 0.867357240485795 GO:0051536 iron-sulfur cluster binding 3/990 76/18639 0.0394736842105263 0.743181818181818 0.775769546122739 0.86823996670488 GO:1901505 carbohydrate derivative transmembrane transporter activity 2/990 53/18639 0.0377358490566038 0.710463121783876 0.780194995254989 0.872272802914166 GO:0003724 RNA helicase activity 3/990 77/18639 0.038961038961039 0.733530106257379 0.783301253515803 0.873903922166421 GO:0051540 metal cluster binding 3/990 77/18639 0.038961038961039 0.733530106257379 0.783301253515803 0.873903922166421 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/990 54/18639 0.037037037037037 0.697306397306397 0.788953812738045 0.879285709364565 GO:0005267 potassium channel activity 5/990 124/18639 0.0403225806451613 0.7591642228739 0.794328875312371 0.882137559491255 GO:0004181 metallocarboxypeptidase activity 1/990 29/18639 0.0344827586206897 0.649216300940439 0.794838366516154 0.882137559491255 GO:0016417 S-acyltransferase activity 1/990 29/18639 0.0344827586206897 0.649216300940439 0.794838366516154 0.882137559491255 GO:0035250 UDP-galactosyltransferase activity 1/990 29/18639 0.0344827586206897 0.649216300940439 0.794838366516154 0.882137559491255 GO:0008238 exopeptidase activity 4/990 102/18639 0.0392156862745098 0.738324420677362 0.797282969037939 0.883506363810859 GO:0008186 ATP-dependent activity, acting on RNA 3/990 79/18639 0.0379746835443038 0.714959723820483 0.797737131508768 0.883506363810859 GO:0033612 receptor serine/threonine kinase binding 1/990 30/18639 0.0333333333333333 0.627575757575758 0.805752392155542 0.890524258413573 GO:0098918 structural constituent of synapse 1/990 30/18639 0.0333333333333333 0.627575757575758 0.805752392155542 0.890524258413573 GO:0004519 endonuclease activity 5/990 127/18639 0.0393700787401575 0.741231209735147 0.811003363214903 0.895394972290334 GO:0016741 transferase activity, transferring one-carbon groups 9/990 215/18639 0.0418604651162791 0.788118393234672 0.812023270505952 0.895589074851159 GO:0008327 methyl-CpG binding 1/990 31/18639 0.032258064516129 0.60733137829912 0.81608637741891 0.8972721724782 GO:0016878 acid-thiol ligase activity 1/990 31/18639 0.032258064516129 0.60733137829912 0.81608637741891 0.8972721724782 GO:0072349 modified amino acid transmembrane transporter activity 1/990 31/18639 0.032258064516129 0.60733137829912 0.81608637741891 0.8972721724782 GO:0008408 3'-5' exonuclease activity 2/990 58/18639 0.0344827586206897 0.649216300940439 0.820978509068275 0.901716561202318 GO:0046906 tetrapyrrole binding 6/990 152/18639 0.0394736842105263 0.743181818181818 0.823928789198485 0.904021143060592 GO:0008378 galactosyltransferase activity 1/990 32/18639 0.03125 0.588352272727273 0.825871119806876 0.904282000118778 GO:0042910 xenobiotic transmembrane transporter activity 1/990 32/18639 0.03125 0.588352272727273 0.825871119806876 0.904282000118778 GO:0004527 exonuclease activity 3/990 84/18639 0.0357142857142857 0.672402597402597 0.830332318190958 0.908229473815058 GO:0005262 calcium channel activity 5/990 131/18639 0.0381679389312977 0.718598195697432 0.83153743741048 0.908610938303316 GO:0042923 neuropeptide binding 1/990 33/18639 0.0303030303030303 0.570523415977962 0.835135783180402 0.910843624522366 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/990 60/18639 0.0333333333333333 0.627575757575758 0.835297687709955 0.910843624522366 GO:0016836 hydro-lyase activity 2/990 61/18639 0.0327868852459016 0.617287630402385 0.842062033159971 0.915527987093726 GO:0015035 protein-disulfide reductase activity 1/990 34/18639 0.0294117647058824 0.553743315508021 0.843907984333331 0.915527987093726 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/990 34/18639 0.0294117647058824 0.553743315508021 0.843907984333331 0.915527987093726 GO:0051427 hormone receptor binding 1/990 34/18639 0.0294117647058824 0.553743315508021 0.843907984333331 0.915527987093726 GO:0090482 vitamin transmembrane transporter activity 1/990 34/18639 0.0294117647058824 0.553743315508021 0.843907984333331 0.915527987093726 GO:0016853 isomerase activity 7/990 180/18639 0.0388888888888889 0.732171717171717 0.848103827855845 0.919140103529164 GO:0099094 ligand-gated monoatomic cation channel activity 5/990 136/18639 0.0367647058823529 0.692179144385027 0.854608786895739 0.923626508902048 GO:0004033 aldo-keto reductase (NADPH) activity 1/990 36/18639 0.0277777777777778 0.522979797979798 0.860078219411144 0.923626508902048 GO:0004190 aspartic-type endopeptidase activity 1/990 36/18639 0.0277777777777778 0.522979797979798 0.860078219411144 0.923626508902048 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/990 36/18639 0.0277777777777778 0.522979797979798 0.860078219411144 0.923626508902048 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/990 36/18639 0.0277777777777778 0.522979797979798 0.860078219411144 0.923626508902048 GO:0016409 palmitoyltransferase activity 1/990 36/18639 0.0277777777777778 0.522979797979798 0.860078219411144 0.923626508902048 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/990 36/18639 0.0277777777777778 0.522979797979798 0.860078219411144 0.923626508902048 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/990 36/18639 0.0277777777777778 0.522979797979798 0.860078219411144 0.923626508902048 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/990 36/18639 0.0277777777777778 0.522979797979798 0.860078219411144 0.923626508902048 GO:0019213 deacetylase activity 1/990 37/18639 0.027027027027027 0.508845208845209 0.867524468015292 0.930680951025505 GO:0008235 metalloexopeptidase activity 2/990 66/18639 0.0303030303030303 0.570523415977962 0.872242345599962 0.934797099678343 GO:0005109 frizzled binding 1/990 38/18639 0.0263157894736842 0.495454545454545 0.874574826937175 0.936351050837883 GO:0015103 inorganic anion transmembrane transporter activity 6/990 165/18639 0.0363636363636364 0.684628099173554 0.87713535370612 0.938145776494147 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/990 39/18639 0.0256410256410256 0.482750582750583 0.881250324025084 0.941597778238282 GO:0022843 voltage-gated monoatomic cation channel activity 5/990 143/18639 0.034965034965035 0.65829624920534 0.882431129488169 0.941910893749444 GO:0015036 disulfide oxidoreductase activity 1/990 40/18639 0.025 0.470681818181818 0.887570871294716 0.946444919038888 GO:0008028 monocarboxylic acid transmembrane transporter activity 2/990 70/18639 0.0285714285714286 0.537922077922078 0.892462218610902 0.949962123098771 GO:0008137 NADH dehydrogenase (ubiquinone) activity 1/990 41/18639 0.024390243902439 0.45920177383592 0.893555324083481 0.949962123098771 GO:0017080 sodium channel regulator activity 1/990 41/18639 0.024390243902439 0.45920177383592 0.893555324083481 0.949962123098771 GO:0008236 serine-type peptidase activity 7/990 194/18639 0.0360824742268041 0.67933458294283 0.895571103847386 0.951152093275352 GO:0042626 ATPase-coupled transmembrane transporter activity 3/990 98/18639 0.0306122448979592 0.576345083487941 0.898602187805672 0.951220389664221 GO:0004520 DNA endonuclease activity 1/990 42/18639 0.0238095238095238 0.448268398268398 0.899221537071832 0.951220389664221 GO:0016859 cis-trans isomerase activity 1/990 42/18639 0.0238095238095238 0.448268398268398 0.899221537071832 0.951220389664221 GO:0031492 nucleosomal DNA binding 1/990 42/18639 0.0238095238095238 0.448268398268398 0.899221537071832 0.951220389664221 GO:0005245 voltage-gated calcium channel activity 1/990 43/18639 0.0232558139534884 0.43784355179704 0.904586417337406 0.954991232631829 GO:0008375 acetylglucosaminyltransferase activity 1/990 43/18639 0.0232558139534884 0.43784355179704 0.904586417337406 0.954991232631829 GO:0019842 vitamin binding 5/990 150/18639 0.0333333333333333 0.627575757575758 0.905571720791405 0.955081109105051 GO:0017171 serine hydrolase activity 7/990 198/18639 0.0353535353535354 0.665610651974288 0.906580440447842 0.955195478962424 GO:0022832 voltage-gated channel activity 6/990 175/18639 0.0342857142857143 0.645506493506493 0.90825175846467 0.95559960301931 GO:0003954 NADH dehydrogenase activity 1/990 44/18639 0.0227272727272727 0.427892561983471 0.909665974598966 0.95559960301931 GO:0016790 thiolester hydrolase activity 1/990 44/18639 0.0227272727272727 0.427892561983471 0.909665974598966 0.95559960301931 GO:0004252 serine-type endopeptidase activity 6/990 176/18639 0.0340909090909091 0.641838842975207 0.910953035143536 0.955846565099757 GO:0016829 lyase activity 7/990 200/18639 0.035 0.658954545454545 0.911702850029174 0.955846565099757 GO:0004180 carboxypeptidase activity 1/990 46/18639 0.0217391304347826 0.409288537549407 0.919028955164845 0.962576230434255 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/990 48/18639 0.0208333333333333 0.392234848484848 0.927422355519796 0.969602782256928 GO:0016835 carbon-oxygen lyase activity 2/990 79/18639 0.0253164556962025 0.476639815880322 0.927565338351349 0.969602782256928 GO:0048306 calcium-dependent protein binding 2/990 80/18639 0.025 0.470681818181818 0.930717058690979 0.971690536102392 GO:0004518 nuclease activity 7/990 209/18639 0.0334928229665072 0.630578512396694 0.931867819995908 0.971690536102392 GO:0015078 proton transmembrane transporter activity 6/990 185/18639 0.0324324324324324 0.610614250614251 0.932310052546876 0.971690536102392 GO:0003743 translation initiation factor activity 1/990 51/18639 0.0196078431372549 0.369162210338681 0.938411063770823 0.976131508491023 GO:0005272 sodium channel activity 1/990 51/18639 0.0196078431372549 0.369162210338681 0.938411063770823 0.976131508491023 GO:0005080 protein kinase C binding 1/990 52/18639 0.0192307692307692 0.362062937062937 0.941691300852106 0.977626683174251 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/990 52/18639 0.0192307692307692 0.362062937062937 0.941691300852106 0.977626683174251 GO:0016860 intramolecular oxidoreductase activity 1/990 53/18639 0.0188679245283019 0.355231560891938 0.944796999036666 0.97989209773011 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/990 54/18639 0.0185185185185185 0.348653198653199 0.947737436513998 0.981023824528148 GO:0050661 NADP binding 1/990 54/18639 0.0185185185185185 0.348653198653199 0.947737436513998 0.981023824528148 GO:0098632 cell-cell adhesion mediator activity 1/990 55/18639 0.0181818181818182 0.342314049586777 0.950521398733591 0.982946592647505 GO:0016758 hexosyltransferase activity 6/990 197/18639 0.0304568527918782 0.573419473927088 0.953687476255209 0.984302885711208 GO:0005261 monoatomic cation channel activity 12/990 341/18639 0.0351906158357771 0.662543321780859 0.95368837559955 0.984302885711208 GO:0005244 voltage-gated monoatomic ion channel activity 5/990 173/18639 0.0289017341040462 0.544140830267998 0.95594779761848 0.985676009011863 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 1/990 58/18639 0.0172413793103448 0.324608150470219 0.958015436617196 0.98684891092315 GO:0052689 carboxylic ester hydrolase activity 2/990 92/18639 0.0217391304347826 0.409288537549407 0.959692427708121 0.987617522597785 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/990 61/18639 0.0163934426229508 0.308643815201192 0.964375397238368 0.991475093478594 GO:0004536 DNA nuclease activity 1/990 64/18639 0.015625 0.294176136363636 0.969772754193793 0.994697439133668 GO:0019843 rRNA binding 1/990 65/18639 0.0153846153846154 0.28965034965035 0.971383789098134 0.994697439133668 GO:0160215 deacylase activity 1/990 65/18639 0.0153846153846154 0.28965034965035 0.971383789098134 0.994697439133668 GO:0015276 ligand-gated monoatomic ion channel activity 5/990 186/18639 0.0268817204301075 0.506109481915934 0.972079567768603 0.994697439133668 GO:0005179 hormone activity 3/990 132/18639 0.0227272727272727 0.427892561983471 0.973893976990365 0.994697439133668 GO:0022834 ligand-gated channel activity 5/990 188/18639 0.0265957446808511 0.500725338491296 0.974008419706813 0.994697439133668 GO:0140098 catalytic activity, acting on RNA 13/990 387/18639 0.0335917312661499 0.632440685929058 0.974072233044186 0.994697439133668 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 1/990 68/18639 0.0147058823529412 0.276871657754011 0.97572021258644 0.99542225534059 GO:0015399 primary active transmembrane transporter activity 4/990 166/18639 0.0240963855421687 0.453669222343921 0.978838929468079 0.996552868169265 GO:0004497 monooxygenase activity 2/990 106/18639 0.0188679245283019 0.355231560891938 0.978904813299921 0.996552868169265 GO:0016874 ligase activity 4/990 167/18639 0.0239520958083832 0.450952640174197 0.979646221960927 0.996552868169265 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/990 73/18639 0.0136986301369863 0.257907845579078 0.981538238817667 0.997521141173894 GO:0098631 cell adhesion mediator activity 1/990 76/18639 0.0131578947368421 0.247727272727273 0.984337024487184 0.997620202425815 GO:0009055 electron transfer activity 2/990 116/18639 0.0172413793103448 0.324608150470219 0.986827258547168 0.997620202425815 GO:0008509 monoatomic anion transmembrane transporter activity 3/990 149/18639 0.0201342281879195 0.379072605247102 0.987297500532404 0.997620202425815 GO:0022853 active monoatomic ion transmembrane transporter activity 2/990 118/18639 0.0169491525423729 0.319106317411402 0.988020032502591 0.997620202425815 GO:0022836 gated channel activity 9/990 318/18639 0.0283018867924528 0.532847341337907 0.988860857637547 0.997620202425815 GO:0005254 chloride channel activity 1/990 83/18639 0.0120481927710843 0.226834611171961 0.989328369141062 0.997620202425815 GO:0015108 chloride transmembrane transporter activity 2/990 121/18639 0.0165289256198347 0.311194590533434 0.989614216668658 0.997620202425815 GO:0008528 G protein-coupled peptide receptor activity 2/990 122/18639 0.0163934426229508 0.308643815201192 0.990098089683679 0.997620202425815 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/990 122/18639 0.0163934426229508 0.308643815201192 0.990098089683679 0.997620202425815 GO:0001653 peptide receptor activity 2/990 128/18639 0.015625 0.294176136363636 0.99257127988349 0.999163309256531 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/990 132/18639 0.0151515151515152 0.285261707988981 0.993872662002007 0.999525018373582 GO:0005216 monoatomic ion channel activity 13/990 448/18639 0.0290178571428571 0.54632711038961 0.995325060531956 0.999932074343513 GO:0005253 monoatomic anion channel activity 1/990 103/18639 0.00970873786407767 0.18278905560459 0.996437537636434 0.999932074343513 GO:0140101 catalytic activity, acting on a tRNA 1/990 139/18639 0.00719424460431655 0.135448005232178 0.999507107631258 0.999932074343513 GO:0045182 translation regulator activity 7/990 356/18639 0.0196629213483146 0.370199182839632 0.999606990683282 0.999932074343513 GO:0030371 translation repressor activity 5/990 329/18639 0.0151975683890578 0.286128764852169 0.999913931789515 0.999932074343513 GO:0003735 structural constituent of ribosome 1/990 175/18639 0.00571428571428571 0.107584415584416 0.999932074343513 0.999932074343513