ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003712	transcription coregulator activity	247/5268	495/18639	0.498989898989899	1.7655035549113	5.97827754256517e-25	8.02882673966503e-22
GO:0051020	GTPase binding	156/5268	315/18639	0.495238095238095	1.75222909209242	7.59812120410959e-16	5.10213838855959e-13
GO:0044389	ubiquitin-like protein ligase binding	158/5268	322/18639	0.490683229813665	1.73611327268354	1.41646774453965e-15	6.34105393638915e-13
GO:0031267	small GTPase binding	142/5268	283/18639	0.501766784452297	1.77532860580986	3.85755034379488e-15	1.29517252792913e-12
GO:0031625	ubiquitin protein ligase binding	149/5268	302/18639	0.493377483443709	1.74564595935977	5.07802596286765e-15	1.36395777362625e-12
GO:0003713	transcription coactivator activity	127/5268	256/18639	0.49609375	1.75525653117882	3.13739752898171e-13	7.0225414690374e-11
GO:0030695	GTPase regulator activity	212/5268	489/18639	0.433537832310838	1.53392400463966	3.6915127300883e-13	7.08243085215512e-11
GO:0060589	nucleoside-triphosphatase regulator activity	212/5268	490/18639	0.43265306122449	1.53079354748733	4.71110056910845e-13	7.90876008039082e-11
GO:0043021	ribonucleoprotein complex binding	95/5268	177/18639	0.536723163841808	1.89900969074553	8.89523382858456e-13	1.32736655908767e-10
GO:0032182	ubiquitin-like protein binding	71/5268	120/18639	0.591666666666667	2.0934083143508	1.36340301415495e-12	1.8310502480101e-10
GO:0019787	ubiquitin-like protein transferase activity	204/5268	479/18639	0.425887265135699	1.50685511292033	7.70499119467781e-12	9.40709379495664e-10
GO:0003714	transcription corepressor activity	103/5268	204/18639	0.504901960784314	1.7864213453035	1.39770969476212e-11	1.56427010005461e-09
GO:0043130	ubiquitin binding	60/5268	100/18639	0.6	2.12289293849658	3.24670139602907e-11	3.35409228835927e-09
GO:0070063	RNA polymerase binding	41/5268	59/18639	0.694915254237288	2.45871781012316	5.75895110899209e-11	5.19185812450558e-09
GO:0140297	DNA-binding transcription factor binding	204/5268	488/18639	0.418032786885246	1.47906475223123	5.7987990966183e-11	5.19185812450558e-09
GO:0016755	aminoacyltransferase activity	206/5268	496/18639	0.415322580645161	1.46947562274965	9.32427914671556e-11	7.82222129863075e-09
GO:0045296	cadherin binding	149/5268	334/18639	0.446107784431138	1.57839844229536	9.90154594763386e-11	7.82222129863075e-09
GO:0042393	histone binding	117/5268	247/18639	0.473684210526316	1.67596810933941	1.15994704963027e-10	8.65449382029698e-09
GO:0004842	ubiquitin-protein transferase activity	189/5268	449/18639	0.420935412026726	1.48933468959114	1.48466572928911e-10	1.04942424970278e-08
GO:0106310	protein serine kinase activity	158/5268	361/18639	0.437673130193906	1.54855532909723	1.58447592695208e-10	1.06397558494832e-08
GO:0000993	RNA polymerase II complex binding	28/5268	36/18639	0.777777777777778	2.75189825360668	9.82628179172935e-10	6.2841411649012e-08
GO:0043022	ribosome binding	62/5268	112/18639	0.553571428571429	1.95862146111292	1.52921142152962e-09	9.33514063233761e-08
GO:0140030	modification-dependent protein binding	86/5268	173/18639	0.497109826589595	1.75885156754052	1.76926928375614e-09	1.03309941221065e-07
GO:0019902	phosphatase binding	92/5268	190/18639	0.484210526315789	1.71321184510251	2.72582402645631e-09	1.52532569480451e-07
GO:0140104	molecular carrier activity	113/5268	249/18639	0.453815261044177	1.60566868842111	5.40968444470101e-09	2.90608248369338e-07
GO:0043175	RNA polymerase core enzyme binding	30/5268	42/18639	0.714285714285714	2.52725349821022	7.96678911299894e-09	3.99467197881561e-07
GO:0004674	protein serine/threonine kinase activity	177/5268	433/18639	0.408775981524249	1.44631274100806	8.03098610781992e-09	3.99467197881561e-07
GO:0004386	helicase activity	77/5268	155/18639	0.496774193548387	1.75766404585201	1.27592249939435e-08	6.11987113102363e-07
GO:0001098	basal transcription machinery binding	38/5268	60/18639	0.633333333333333	2.24083143507973	1.60521577696154e-08	7.18601596153115e-07
GO:0001099	basal RNA polymerase II transcription machinery binding	38/5268	60/18639	0.633333333333333	2.24083143507973	1.60521577696154e-08	7.18601596153115e-07
GO:0140597	protein carrier chaperone	88/5268	188/18639	0.468085106382979	1.65615761159308	4.48762417244549e-08	1.90106710487931e-06
GO:0005096	GTPase activator activity	118/5268	271/18639	0.435424354243542	1.54059881145508	4.5297205775233e-08	1.90106710487931e-06
GO:0005525	GTP binding	154/5268	378/18639	0.407407407407407	1.44147051379398	9.53432106463506e-08	3.88017975448633e-06
GO:0140098	catalytic activity, acting on RNA	157/5268	387/18639	0.405684754521964	1.43537550105066	9.91685926898567e-08	3.91715941124934e-06
GO:0005085	guanyl-nucleotide exchange factor activity	102/5268	230/18639	0.443478260869565	1.56909478062791	1.2189141446876e-07	4.67714770375843e-06
GO:0019903	protein phosphatase binding	70/5268	144/18639	0.486111111111111	1.71993640850418	1.70421286310307e-07	6.3576607642984e-06
GO:0140857	histone H3T45 kinase activity	107/5268	246/18639	0.434959349593496	1.53895355297517	2.01154058408945e-07	7.30134866062737e-06
GO:0015631	tubulin binding	155/5268	385/18639	0.402597402597403	1.42445197171849	2.1066342347931e-07	7.35257438748153e-06
GO:0140097	catalytic activity, acting on DNA	138/5268	336/18639	0.410714285714286	1.45317076147088	2.5013400684668e-07	7.35257438748153e-06
GO:0035402	histone H3T11 kinase activity	107/5268	247/18639	0.433198380566802	1.53272297178903	2.5709679986431e-07	7.35257438748153e-06
GO:0004676	3-phosphoinositide-dependent protein kinase activity	106/5268	245/18639	0.43265306122449	1.53079354748733	3.14595371335481e-07	7.35257438748153e-06
GO:0004711	ribosomal protein S6 kinase activity	106/5268	245/18639	0.43265306122449	1.53079354748733	3.14595371335481e-07	7.35257438748153e-06
GO:0035175	histone H3S10 kinase activity	106/5268	245/18639	0.43265306122449	1.53079354748733	3.14595371335481e-07	7.35257438748153e-06
GO:0035979	histone H2AXS139 kinase activity	106/5268	245/18639	0.43265306122449	1.53079354748733	3.14595371335481e-07	7.35257438748153e-06
GO:0044022	histone H3S28 kinase activity	106/5268	245/18639	0.43265306122449	1.53079354748733	3.14595371335481e-07	7.35257438748153e-06
GO:0044023	histone H4S1 kinase activity	106/5268	245/18639	0.43265306122449	1.53079354748733	3.14595371335481e-07	7.35257438748153e-06
GO:0044024	histone H2AS1 kinase activity	106/5268	245/18639	0.43265306122449	1.53079354748733	3.14595371335481e-07	7.35257438748153e-06
GO:0044025	histone H2BS14 kinase activity	106/5268	245/18639	0.43265306122449	1.53079354748733	3.14595371335481e-07	7.35257438748153e-06
GO:0072354	histone H3T3 kinase activity	106/5268	245/18639	0.43265306122449	1.53079354748733	3.14595371335481e-07	7.35257438748153e-06
GO:0072371	histone H2AS121 kinase activity	106/5268	245/18639	0.43265306122449	1.53079354748733	3.14595371335481e-07	7.35257438748153e-06
GO:0072518	Rho-dependent protein serine/threonine kinase activity	106/5268	245/18639	0.43265306122449	1.53079354748733	3.14595371335481e-07	7.35257438748153e-06
GO:0140823	histone H2BS36 kinase activity	106/5268	245/18639	0.43265306122449	1.53079354748733	3.14595371335481e-07	7.35257438748153e-06
GO:0140855	histone H3S57 kinase activity	106/5268	245/18639	0.43265306122449	1.53079354748733	3.14595371335481e-07	7.35257438748153e-06
GO:0140995	histone H2A kinase activity	106/5268	245/18639	0.43265306122449	1.53079354748733	3.14595371335481e-07	7.35257438748153e-06
GO:0140997	histone H4 kinase activity	106/5268	245/18639	0.43265306122449	1.53079354748733	3.14595371335481e-07	7.35257438748153e-06
GO:0140998	histone H2B kinase activity	106/5268	245/18639	0.43265306122449	1.53079354748733	3.14595371335481e-07	7.35257438748153e-06
GO:1990244	histone H2AT120 kinase activity	106/5268	245/18639	0.43265306122449	1.53079354748733	3.14595371335481e-07	7.35257438748153e-06
GO:0042162	telomeric DNA binding	26/5268	38/18639	0.684210526315789	2.42084282460137	3.17534858133975e-07	7.35257438748153e-06
GO:0004679	AMP-activated protein kinase activity	107/5268	248/18639	0.431451612903226	1.52654263722537	3.27596179725893e-07	7.45697744698091e-06
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	105/5268	243/18639	0.432098765432099	1.52883236311482	3.84846656235484e-07	8.61415098873758e-06
GO:0004677	DNA-dependent protein kinase activity	106/5268	246/18639	0.430894308943089	1.52457080948942	4.00486651122742e-07	8.81727167963676e-06
GO:0141003	histone H2AX kinase activity	143/5268	354/18639	0.403954802259887	1.42925466198216	4.87491032752589e-07	1.05596847901085e-05
GO:0140658	ATP-dependent chromatin remodeler activity	74/5268	158/18639	0.468354430379747	1.65711052161126	4.98244669346196e-07	1.06213109671737e-05
GO:0035403	histone H3T6 kinase activity	106/5268	247/18639	0.42914979757085	1.51839845803399	5.08283276891476e-07	1.06660068885196e-05
GO:0019001	guanyl nucleotide binding	158/5268	400/18639	0.395	1.39757118451025	6.51302478033631e-07	1.3253018606048e-05
GO:0032561	guanyl ribonucleotide binding	158/5268	400/18639	0.395	1.39757118451025	6.51302478033631e-07	1.3253018606048e-05
GO:0140996	histone H3 kinase activity	143/5268	357/18639	0.400560224089636	1.41724411860416	8.64095537338523e-07	1.71988263579641e-05
GO:0035173	histone kinase activity	144/5268	360/18639	0.4	1.41526195899772	8.70826651036159e-07	1.71988263579641e-05
GO:0016887	ATP hydrolysis activity	163/5268	417/18639	0.390887290167866	1.38301978007571	9.33113161510128e-07	1.81618982015667e-05
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	140/5268	349/18639	0.401146131805158	1.41931715085731	1.0178190944731e-06	1.95275863411054e-05
GO:0001221	transcription coregulator binding	57/5268	115/18639	0.495652173913044	1.75369416658413	1.04045630722127e-06	1.96807439520869e-05
GO:0061775	cohesin loader activity	71/5268	153/18639	0.464052287581699	1.64188887400063	1.28976128643992e-06	2.40576306623447e-05
GO:0001222	transcription corepressor binding	30/5268	49/18639	0.612244897959184	2.16621728418019	1.4900167095186e-06	2.7412225217582e-05
GO:0000510	H3-H4 histone complex chaperone activity	70/5268	151/18639	0.463576158940397	1.64020425711657	1.59941665690058e-06	2.78963190937336e-05
GO:0140584	chromatin extrusion motor activity	70/5268	151/18639	0.463576158940397	1.64020425711657	1.59941665690058e-06	2.78963190937336e-05
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	70/5268	151/18639	0.463576158940397	1.64020425711657	1.59941665690058e-06	2.78963190937336e-05
GO:0140849	ATP-dependent H2AZ histone chaperone activity	70/5268	151/18639	0.463576158940397	1.64020425711657	1.59941665690058e-06	2.78963190937336e-05
GO:0008094	ATP-dependent activity, acting on DNA	91/5268	210/18639	0.433333333333333	1.53320045558087	1.92572975753815e-06	3.31571162099196e-05
GO:0015616	DNA translocase activity	70/5268	152/18639	0.460526315789474	1.62941343963554	2.15149841393097e-06	3.61182796238661e-05
GO:0140674	ATP-dependent histone chaperone activity	70/5268	152/18639	0.460526315789474	1.62941343963554	2.15149841393097e-06	3.61182796238661e-05
GO:0140713	histone chaperone activity	74/5268	164/18639	0.451219512195122	1.59648452691816	2.87382351027133e-06	4.75404214236753e-05
GO:0061650	ubiquitin-like protein conjugating enzyme activity	26/5268	41/18639	0.634146341463415	2.24370798377688	2.90269140487072e-06	4.75404214236753e-05
GO:0016922	nuclear receptor binding	64/5268	137/18639	0.467153284671533	1.65286068204114	3.18694615190336e-06	5.15670925542917e-05
GO:0003779	actin binding	169/5268	443/18639	0.381489841986456	1.34977015276871	3.40792870572703e-06	5.44862887118024e-05
GO:0003689	DNA clamp loader activity	72/5268	160/18639	0.45	1.59216970387244	4.38109568961653e-06	6.92213118959413e-05
GO:0140938	histone H3 methyltransferase activity	28/5268	47/18639	0.595744680851064	2.10783696020937	7.08383974275984e-06	0.000110623218308447
GO:0061659	ubiquitin-like protein ligase activity	144/5268	372/18639	0.387096774193548	1.36960834741715	7.23259321658884e-06	0.00011164796195263
GO:0003924	GTPase activity	130/5268	331/18639	0.392749244712991	1.38960766366846	8.61563751096375e-06	0.000131486377013913
GO:0003724	RNA helicase activity	40/5268	77/18639	0.519480519480519	1.83800254415289	9.74433108155674e-06	0.00014704086115203
GO:0000149	SNARE binding	51/5268	106/18639	0.481132075471698	1.70231980917179	1.10773114056919e-05	0.000165298102420492
GO:0008017	microtubule binding	111/5268	276/18639	0.402173913043478	1.42295360007923	1.12067829569302e-05	0.000165392412210519
GO:0003725	double-stranded RNA binding	39/5268	75/18639	0.52	1.83984054669704	1.21593349320724e-05	0.000177499856671448
GO:0061631	ubiquitin conjugating enzyme activity	22/5268	35/18639	0.628571428571429	2.22398307842499	2.08108587586629e-05	0.000300526702289078
GO:0008186	ATP-dependent activity, acting on RNA	40/5268	79/18639	0.506329113924051	1.79147083417433	2.15054932949325e-05	0.000304019763106257
GO:0046332	SMAD binding	40/5268	79/18639	0.506329113924051	1.79147083417433	2.15054932949325e-05	0.000304019763106257
GO:0042054	histone methyltransferase activity	35/5268	67/18639	0.522388059701492	1.84828987182538	2.95237199755519e-05	0.000413024540907981
GO:0031072	heat shock protein binding	59/5268	131/18639	0.450381679389313	1.59352014467301	2.98636570440682e-05	0.00041347310732148
GO:0019003	GDP binding	38/5268	75/18639	0.506666666666667	1.79266514806378	3.36011441296434e-05	0.000460472822103174
GO:0048156	tau protein binding	25/5268	43/18639	0.581395348837209	2.05706680086878	3.91041618994474e-05	0.000526950393818403
GO:0005484	SNAP receptor activity	22/5268	36/18639	0.611111111111111	2.16220577069096	3.92368126447061e-05	0.000526950393818403
GO:0019211	phosphatase activator activity	17/5268	25/18639	0.68	2.40594533029613	4.22641049257726e-05	0.000556477381522672
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	17/5268	25/18639	0.68	2.40594533029613	4.22641049257726e-05	0.000556477381522672
GO:0061630	ubiquitin protein ligase activity	134/5268	353/18639	0.379603399433428	1.34309562681087	4.41783018559576e-05	0.000576033586335447
GO:0035091	phosphatidylinositol binding	111/5268	284/18639	0.390845070422535	1.382870400077	4.8051170193661e-05	0.000620506938173911
GO:0140034	methylation-dependent protein binding	38/5268	76/18639	0.5	1.76907744874715	4.90021936793314e-05	0.000626761391536591
GO:0051010	microtubule plus-end binding	15/5268	21/18639	0.714285714285714	2.52725349821022	5.00894636494443e-05	0.000634624053596262
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	71/5268	167/18639	0.425149700598802	1.50424549534189	5.22762804928976e-05	0.000656140604691229
GO:0016779	nucleotidyltransferase activity	60/5268	136/18639	0.441176470588235	1.56095069007102	5.41086327168977e-05	0.000672850867951792
GO:0003743	translation initiation factor activity	28/5268	51/18639	0.549019607843137	1.9425164143106	5.70970557264956e-05	0.000703498585694344
GO:0019208	phosphatase regulator activity	53/5268	117/18639	0.452991452991453	1.60275392792477	6.12473164666821e-05	0.000747774054679582
GO:0051219	phosphoprotein binding	44/5268	93/18639	0.473118279569892	1.67396575795429	7.17795958329234e-05	0.00086189018513969
GO:0031593	polyubiquitin modification-dependent protein binding	31/5268	59/18639	0.525423728813559	1.85903053936141	7.18776624986189e-05	0.00086189018513969
GO:0141052	histone H3 demethylase activity	18/5268	28/18639	0.642857142857143	2.2745281483892	7.74373281362719e-05	0.000920339218469143
GO:0035198	miRNA binding	24/5268	42/18639	0.571428571428571	2.02180279856817	8.17408788651918e-05	0.000962964915052216
GO:0099122	RNA polymerase II C-terminal domain binding	9/5268	10/18639	0.9	3.18433940774488	8.54246083773799e-05	0.000995179640851462
GO:0051082	unfolded protein binding	54/5268	121/18639	0.446280991735537	1.57901127656771	8.595743733341e-05	0.000995179640851462
GO:0008135	translation factor activity, RNA binding	40/5268	83/18639	0.481927710843373	1.7051348903587	9.03944073298072e-05	0.00103760417986266
GO:0019887	protein kinase regulator activity	100/5268	255/18639	0.392156862745098	1.38751172450757	9.53625948703291e-05	0.00108535563483773
GO:0070034	telomerase RNA binding	15/5268	22/18639	0.681818181818182	2.41237833920066	0.000116170894260206	0.00131107152093661
GO:0004860	protein kinase inhibitor activity	40/5268	84/18639	0.476190476190476	1.68483566547348	0.000125841856977575	0.00139674061091639
GO:0180051	translation factor activity	40/5268	84/18639	0.476190476190476	1.68483566547348	0.000125841856977575	0.00139674061091639
GO:0008408	3'-5' exonuclease activity	30/5268	58/18639	0.517241379310345	1.83008011939361	0.000136049754937154	0.00149766246623441
GO:0044390	ubiquitin-like protein conjugating enzyme binding	21/5268	36/18639	0.583333333333333	2.06392369020501	0.000151811068130529	0.00165757938617317
GO:0035064	methylated histone binding	36/5268	74/18639	0.486486486486487	1.72126454472696	0.000156969876075719	0.00170008502878783
GO:0002039	p53 binding	34/5268	69/18639	0.492753623188406	1.74343864514212	0.000173014354710654	0.00185886622701127
GO:0019207	kinase regulator activity	109/5268	287/18639	0.379790940766551	1.34375917709714	0.000211816462230388	0.00225769451409056
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	55/5268	128/18639	0.4296875	1.52030093251708	0.000250011038058062	0.00264381751269273
GO:0032452	histone demethylase activity	18/5268	30/18639	0.6	2.12289293849658	0.000276541804251469	0.00287903599309862
GO:0051721	protein phosphatase 2A binding	18/5268	30/18639	0.6	2.12289293849658	0.000276541804251469	0.00287903599309862
GO:1990841	promoter-specific chromatin binding	33/5268	68/18639	0.485294117647059	1.71704575907812	0.000307668766055486	0.00317845502163475
GO:0008170	N-methyltransferase activity	44/5268	98/18639	0.448979591836735	1.58855934173214	0.000316945937125566	0.00324930071419569
GO:0005520	insulin-like growth factor binding	13/5268	19/18639	0.684210526315789	2.42084282460137	0.000321734489025792	0.00327340468758817
GO:0032451	demethylase activity	22/5268	40/18639	0.55	1.94598519362187	0.00033992757245284	0.00343250172785086
GO:0019210	kinase inhibitor activity	41/5268	90/18639	0.455555555555556	1.61182611996963	0.000344017865500754	0.00344788054751875
GO:0003697	single-stranded DNA binding	52/5268	121/18639	0.429752066115702	1.52052937743557	0.00036176651822523	0.00359890691834432
GO:0061980	regulatory RNA binding	29/5268	58/18639	0.5	1.76907744874715	0.000371495118213988	0.00366851429236313
GO:0031994	insulin-like growth factor I binding	10/5268	13/18639	0.769230769230769	2.72165761345716	0.000380988396396011	0.00370773490115828
GO:0046975	histone H3K36 methyltransferase activity	10/5268	13/18639	0.769230769230769	2.72165761345716	0.000380988396396011	0.00370773490115828
GO:0019905	syntaxin binding	30/5268	61/18639	0.491803278688525	1.74007617909556	0.000426481566149473	0.00412060966430749
GO:0016279	protein-lysine N-methyltransferase activity	33/5268	69/18639	0.478260869565217	1.69216103793206	0.000431101976454917	0.00413549967413538
GO:0140457	protein demethylase activity	18/5268	31/18639	0.580645161290323	2.05441252112573	0.000485781321616472	0.00462698095695689
GO:0051087	protein-folding chaperone binding	56/5268	134/18639	0.417910447761194	1.47863189746031	0.000515323089822599	0.00487379513825177
GO:0044183	protein folding chaperone	35/5268	75/18639	0.466666666666667	1.65113895216401	0.000523382351256667	0.00491540208208184
GO:0005543	phospholipid binding	174/5268	497/18639	0.35010060362173	1.23871016531994	0.000530274340928259	0.00494554472129619
GO:0016278	lysine N-methyltransferase activity	33/5268	70/18639	0.471428571428571	1.66798730881874	0.000596397277487784	0.00552387271493858
GO:0000287	magnesium ion binding	88/5268	230/18639	0.382608695652174	1.35372883034565	0.000621459884037431	0.00571657961823472
GO:0061608	nuclear import signal receptor activity	13/5268	20/18639	0.65	2.2998006833713	0.000681258684589454	0.00622401641771181
GO:0008168	methyltransferase activity	79/5268	204/18639	0.387254901960784	1.37016782795123	0.000757944782171857	0.00680532221825132
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	29/5268	60/18639	0.483333333333333	1.71010820045558	0.000758252609038623	0.00680532221825132
GO:0019888	protein phosphatase regulator activity	46/5268	107/18639	0.429906542056075	1.52107593724054	0.000760088110750334	0.00680532221825132
GO:0030515	snoRNA binding	18/5268	32/18639	0.5625	1.99021212984055	0.000818378920428864	0.00718354830154226
GO:0051059	NF-kappaB binding	18/5268	32/18639	0.5625	1.99021212984055	0.000818378920428864	0.00718354830154226
GO:0140142	nucleocytoplasmic carrier activity	18/5268	32/18639	0.5625	1.99021212984055	0.000818378920428864	0.00718354830154226
GO:0016407	acetyltransferase activity	42/5268	96/18639	0.4375	1.54794276765376	0.000824465630480237	0.00718998273853869
GO:0008174	mRNA methyltransferase activity	10/5268	14/18639	0.714285714285714	2.52725349821022	0.000994350087693136	0.00856033440879412
GO:0032454	histone H3K9 demethylase activity	10/5268	14/18639	0.714285714285714	2.52725349821022	0.000994350087693136	0.00856033440879412
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	8/5268	10/18639	0.8	2.83052391799544	0.00102555291624449	0.00866237463217833
GO:0016427	tRNA (cytidine) methyltransferase activity	8/5268	10/18639	0.8	2.83052391799544	0.00102555291624449	0.00866237463217833
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	8/5268	10/18639	0.8	2.83052391799544	0.00102555291624449	0.00866237463217833
GO:0035259	nuclear glucocorticoid receptor binding	9/5268	12/18639	0.75	2.65361617312073	0.00104940882508823	0.00880847532558434
GO:0140296	general transcription initiation factor binding	26/5268	53/18639	0.490566037735849	1.73569862895947	0.00105855181627086	0.00883003161025942
GO:0035591	signaling adaptor activity	53/5268	129/18639	0.410852713178295	1.45366053928061	0.0011462160979253	0.00950227295996097
GO:0008276	protein methyltransferase activity	41/5268	95/18639	0.431578947368421	1.52699316628702	0.00130600296794073	0.010760502981254
GO:0072542	protein phosphatase activator activity	13/5268	21/18639	0.619047619047619	2.19028636511552	0.00132639018326188	0.0108618415617116
GO:0019783	ubiquitin-like protein peptidase activity	52/5268	127/18639	0.409448818897638	1.44869334385594	0.0013891812487203	0.0113070934365537
GO:0004527	exonuclease activity	37/5268	84/18639	0.44047619047619	1.55847299056297	0.00140909961075391	0.0114001251641114
GO:0004721	phosphoprotein phosphatase activity	68/5268	175/18639	0.388571428571429	1.37482590302636	0.00152821722705741	0.0122897948259766
GO:0016741	transferase activity, transferring one-carbon groups	81/5268	215/18639	0.376744186046512	1.33297928696297	0.00167251352910027	0.0132964570374157
GO:0060590	ATPase regulator activity	24/5268	49/18639	0.489795918367347	1.73297382734415	0.00167319526382968	0.0132964570374157
GO:0005080	protein kinase C binding	25/5268	52/18639	0.480769230769231	1.70103600841072	0.00188162089860851	0.0148648050990072
GO:0032183	SUMO binding	11/5268	17/18639	0.647058823529412	2.28939434543749	0.00189905529583674	0.0149148027035599
GO:0003684	damaged DNA binding	33/5268	74/18639	0.445945945945946	1.57782583266638	0.00194259519598356	0.0151680543500344
GO:0061733	protein-lysine-acetyltransferase activity	23/5268	47/18639	0.48936170212766	1.73143750302913	0.00210567669765075	0.0162524356606032
GO:1990518	single-stranded 3'-5' DNA helicase activity	23/5268	47/18639	0.48936170212766	1.73143750302913	0.00210567669765075	0.0162524356606032
GO:0061578	K63-linked deubiquitinase activity	10/5268	15/18639	0.666666666666667	2.35876993166287	0.00222692222391823	0.017090037409841
GO:0004402	histone acetyltransferase activity	21/5268	42/18639	0.5	1.76907744874715	0.00232153835104123	0.0174655140751151
GO:0048487	beta-tubulin binding	21/5268	42/18639	0.5	1.76907744874715	0.00232153835104123	0.0174655140751151
GO:0051879	Hsp90 protein binding	21/5268	42/18639	0.5	1.76907744874715	0.00232153835104123	0.0174655140751151
GO:0016791	phosphatase activity	99/5268	273/18639	0.362637362637363	1.2830671606298	0.00232786821998928	0.0174655140751151
GO:0050321	tau-protein kinase activity	13/5268	22/18639	0.590909090909091	2.09072789397391	0.0024068185414335	0.0179575405619177
GO:0003727	single-stranded RNA binding	38/5268	89/18639	0.426966292134831	1.51067287758184	0.00242678290093852	0.0180064609721571
GO:0008432	JUN kinase binding	8/5268	11/18639	0.727272727272727	2.57320356181404	0.00282469409009536	0.020617196538033
GO:0034511	U3 snoRNA binding	8/5268	11/18639	0.727272727272727	2.57320356181404	0.00282469409009536	0.020617196538033
GO:0070990	snRNP binding	8/5268	11/18639	0.727272727272727	2.57320356181404	0.00282469409009536	0.020617196538033
GO:0004532	RNA exonuclease activity	20/5268	40/18639	0.5	1.76907744874715	0.00292877495221037	0.021020161728473
GO:0140662	ATP-dependent protein folding chaperone	20/5268	40/18639	0.5	1.76907744874715	0.00292877495221037	0.021020161728473
GO:0000339	RNA cap binding	12/5268	20/18639	0.6	2.12289293849658	0.00296659037670931	0.021020161728473
GO:0015095	magnesium ion transmembrane transporter activity	12/5268	20/18639	0.6	2.12289293849658	0.00296659037670931	0.021020161728473
GO:0036121	double-stranded DNA helicase activity	23/5268	48/18639	0.479166666666667	1.69536588838269	0.00297381290276238	0.021020161728473
GO:0043138	3'-5' DNA helicase activity	23/5268	48/18639	0.479166666666667	1.69536588838269	0.00297381290276238	0.021020161728473
GO:0000175	3'-5'-RNA exonuclease activity	18/5268	35/18639	0.514285714285714	1.81962251871136	0.00316442973328775	0.0221345267281534
GO:0010485	histone H4 acetyltransferase activity	18/5268	35/18639	0.514285714285714	1.81962251871136	0.00316442973328775	0.0221345267281534
GO:0017022	myosin binding	33/5268	76/18639	0.434210526315789	1.53630410022779	0.00328833934941452	0.0225529006337455
GO:0035925	mRNA 3'-UTR AU-rich region binding	16/5268	30/18639	0.533333333333333	1.8870159453303	0.00330820657099617	0.0225529006337455
GO:0043995	histone H4K5 acetyltransferase activity	16/5268	30/18639	0.533333333333333	1.8870159453303	0.00330820657099617	0.0225529006337455
GO:0043996	histone H4K8 acetyltransferase activity	16/5268	30/18639	0.533333333333333	1.8870159453303	0.00330820657099617	0.0225529006337455
GO:0043997	histone H4K12 acetyltransferase activity	16/5268	30/18639	0.533333333333333	1.8870159453303	0.00330820657099617	0.0225529006337455
GO:0019843	rRNA binding	29/5268	65/18639	0.446153846153846	1.57856141580515	0.00351743403486265	0.0238581510546492
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	11/5268	18/18639	0.611111111111111	2.16220577069096	0.00364032198341414	0.0245676001192221
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	19/5268	38/18639	0.5	1.76907744874715	0.00369845576266337	0.0247115725833677
GO:0043531	ADP binding	19/5268	38/18639	0.5	1.76907744874715	0.00369845576266337	0.0247115725833677
GO:0003678	DNA helicase activity	32/5268	74/18639	0.432432432432432	1.53001292864619	0.00406108207405653	0.0270001644824649
GO:0044013	histone H2B acetyltransferase activity	13/5268	23/18639	0.565217391304348	1.99982668119243	0.00411282403040359	0.027165712460534
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	27/5268	60/18639	0.45	1.59216970387244	0.00412643733577732	0.027165712460534
GO:0036408	histone H3K14 acetyltransferase activity	15/5268	28/18639	0.535714285714286	1.89544012365766	0.00417575747344778	0.0272235062467979
GO:0051019	mitogen-activated protein kinase binding	15/5268	28/18639	0.535714285714286	1.89544012365766	0.00417575747344778	0.0272235062467979
GO:0051015	actin filament binding	77/5268	209/18639	0.368421052631579	1.30353075170843	0.00420835300030243	0.0273034689826385
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	10/5268	16/18639	0.625	2.21134681093394	0.00443839118504159	0.0281167894410889
GO:0030275	LRR domain binding	10/5268	16/18639	0.625	2.21134681093394	0.00443839118504159	0.0281167894410889
GO:0034450	ubiquitin-ubiquitin ligase activity	10/5268	16/18639	0.625	2.21134681093394	0.00443839118504159	0.0281167894410889
GO:0070411	I-SMAD binding	10/5268	16/18639	0.625	2.21134681093394	0.00443839118504159	0.0281167894410889
GO:0140327	flippase activity	10/5268	16/18639	0.625	2.21134681093394	0.00443839118504159	0.0281167894410889
GO:0004725	protein tyrosine phosphatase activity	40/5268	98/18639	0.408163265306122	1.44414485612012	0.00497059426670069	0.031340413615864
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	83/5268	229/18639	0.362445414847162	1.28238801961584	0.00504724284327043	0.0316749866285616
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	12/5268	21/18639	0.571428571428571	2.02180279856817	0.00515352396797252	0.0320425124490143
GO:0035613	RNA stem-loop binding	12/5268	21/18639	0.571428571428571	2.02180279856817	0.00515352396797252	0.0320425124490143
GO:0061749	forked DNA-dependent helicase activity	22/5268	47/18639	0.468085106382979	1.65615761159308	0.00518238053398992	0.0320734426596704
GO:0050750	low-density lipoprotein particle receptor binding	14/5268	26/18639	0.538461538461538	1.90516032942001	0.00527593593379346	0.0323542555209343
GO:0070412	R-SMAD binding	14/5268	26/18639	0.538461538461538	1.90516032942001	0.00527593593379346	0.0323542555209343
GO:0016776	phosphotransferase activity, phosphate group as acceptor	19/5268	39/18639	0.487179487179487	1.72371648852287	0.00532441561904423	0.0325031371653473
GO:0015605	organophosphate ester transmembrane transporter activity	23/5268	50/18639	0.46	1.62755125284738	0.00562326953401209	0.0341721763989966
GO:0034212	protein N-acetyltransferase activity	24/5268	53/18639	0.452830188679245	1.60218334980874	0.00603383417369106	0.0365019788075094
GO:0004843	cysteine-type deubiquitinase activity	43/5268	108/18639	0.398148148148148	1.40870982029866	0.00624548278755738	0.037612929971702
GO:0000995	RNA polymerase III general transcription initiation factor activity	8/5268	12/18639	0.666666666666667	2.35876993166287	0.00637526462010962	0.0377802901737248
GO:0005095	GTPase inhibitor activity	8/5268	12/18639	0.666666666666667	2.35876993166287	0.00637526462010962	0.0377802901737248
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	15/5268	29/18639	0.517241379310345	1.83008011939361	0.00641392863708804	0.0377802901737248
GO:0010484	histone H3 acetyltransferase activity	15/5268	29/18639	0.517241379310345	1.83008011939361	0.00641392863708804	0.0377802901737248
GO:0097472	cyclin-dependent protein kinase activity	15/5268	29/18639	0.517241379310345	1.83008011939361	0.00641392863708804	0.0377802901737248
GO:0042800	histone H3K4 methyltransferase activity	11/5268	19/18639	0.578947368421053	2.04840546697039	0.00645210158863217	0.0378391809324585
GO:0043998	histone H2A acetyltransferase activity	13/5268	24/18639	0.541666666666667	1.91650056947608	0.00667299028414902	0.0389644606591832
GO:0045309	protein phosphorylated amino acid binding	26/5268	59/18639	0.440677966101695	1.55918690398054	0.00676238607175549	0.0393155172916347
GO:0009378	four-way junction helicase activity	22/5268	48/18639	0.458333333333333	1.62165432801822	0.00705116852964402	0.0408177557556548
GO:0140789	histone phosphatase activity	52/5268	136/18639	0.382352941176471	1.35282393139488	0.00738893673900931	0.0421309393703397
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	7/5268	10/18639	0.7	2.47670842824601	0.00739624307546668	0.0421309393703397
GO:0050815	phosphoserine residue binding	7/5268	10/18639	0.7	2.47670842824601	0.00739624307546668	0.0421309393703397
GO:0015036	disulfide oxidoreductase activity	19/5268	40/18639	0.475	1.68062357630979	0.00749190003189391	0.0421309393703397
GO:0061791	GTPase motor activity	19/5268	40/18639	0.475	1.68062357630979	0.00749190003189391	0.0421309393703397
GO:1990606	membrane scission GTPase motor activity	19/5268	40/18639	0.475	1.68062357630979	0.00749190003189391	0.0421309393703397
GO:0042826	histone deacetylase binding	49/5268	127/18639	0.385826771653543	1.3651148817104	0.0075000493191552	0.0421309393703397
GO:0005048	signal sequence binding	23/5268	51/18639	0.450980392156863	1.59563848318371	0.00754466875699654	0.0421309393703397
GO:0101005	deubiquitinase activity	45/5268	115/18639	0.391304347826087	1.38449539467168	0.00756035471947272	0.0421309393703397
GO:0017069	snRNA binding	24/5268	54/18639	0.444444444444444	1.57251328777525	0.00799634441033392	0.0428217854882921
GO:0140463	chromatin-protein adaptor activity	24/5268	54/18639	0.444444444444444	1.57251328777525	0.00799634441033392	0.0428217854882921
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	10/5268	17/18639	0.588235294117647	2.08126758676136	0.00806601388390565	0.0428217854882921
GO:0032977	membrane insertase activity	10/5268	17/18639	0.588235294117647	2.08126758676136	0.00806601388390565	0.0428217854882921
GO:0048038	quinone binding	10/5268	17/18639	0.588235294117647	2.08126758676136	0.00806601388390565	0.0428217854882921
GO:0001671	ATPase activator activity	14/5268	27/18639	0.518518518518518	1.83459883573779	0.00813984231609233	0.0428217854882921
GO:0004407	histone deacetylase activity	12/5268	22/18639	0.545454545454545	1.92990267136053	0.00844957047981936	0.0428217854882921
GO:0032931	histone H3K56 acetyltransferase activity	12/5268	22/18639	0.545454545454545	1.92990267136053	0.00844957047981936	0.0428217854882921
GO:0033558	protein lysine deacetylase activity	12/5268	22/18639	0.545454545454545	1.92990267136053	0.00844957047981936	0.0428217854882921
GO:0034062	5'-3' RNA polymerase activity	12/5268	22/18639	0.545454545454545	1.92990267136053	0.00844957047981936	0.0428217854882921
GO:0043992	histone H3K9 acetyltransferase activity	12/5268	22/18639	0.545454545454545	1.92990267136053	0.00844957047981936	0.0428217854882921
GO:0043993	histone H3K18 acetyltransferase activity	12/5268	22/18639	0.545454545454545	1.92990267136053	0.00844957047981936	0.0428217854882921
GO:0043994	histone H3K23 acetyltransferase activity	12/5268	22/18639	0.545454545454545	1.92990267136053	0.00844957047981936	0.0428217854882921
GO:0043999	histone H2AK5 acetyltransferase activity	12/5268	22/18639	0.545454545454545	1.92990267136053	0.00844957047981936	0.0428217854882921
GO:0044012	histone H2AK9 acetyltransferase activity	12/5268	22/18639	0.545454545454545	1.92990267136053	0.00844957047981936	0.0428217854882921
GO:0044014	histone H2BK5 acetyltransferase activity	12/5268	22/18639	0.545454545454545	1.92990267136053	0.00844957047981936	0.0428217854882921
GO:0044015	histone H2BK12 acetyltransferase activity	12/5268	22/18639	0.545454545454545	1.92990267136053	0.00844957047981936	0.0428217854882921
GO:0044016	histone H3K4 acetyltransferase activity	12/5268	22/18639	0.545454545454545	1.92990267136053	0.00844957047981936	0.0428217854882921
GO:0044017	histone H3K27 acetyltransferase activity	12/5268	22/18639	0.545454545454545	1.92990267136053	0.00844957047981936	0.0428217854882921
GO:0044018	histone H3K36 acetyltransferase activity	12/5268	22/18639	0.545454545454545	1.92990267136053	0.00844957047981936	0.0428217854882921
GO:0046972	histone H4K16 acetyltransferase activity	12/5268	22/18639	0.545454545454545	1.92990267136053	0.00844957047981936	0.0428217854882921
GO:0097747	RNA polymerase activity	12/5268	22/18639	0.545454545454545	1.92990267136053	0.00844957047981936	0.0428217854882921
GO:0140035	ubiquitin-like protein reader activity	12/5268	22/18639	0.545454545454545	1.92990267136053	0.00844957047981936	0.0428217854882921
GO:0140908	histone H3K122 acetyltransferase activity	12/5268	22/18639	0.545454545454545	1.92990267136053	0.00844957047981936	0.0428217854882921
GO:0030291	protein serine/threonine kinase inhibitor activity	21/5268	46/18639	0.456521739130435	1.61524462711697	0.00884549569521769	0.0446597771378848
GO:0016763	pentosyltransferase activity	22/5268	49/18639	0.448979591836735	1.58855934173214	0.00943597606992374	0.047462606224373
GO:0031624	ubiquitin conjugating enzyme binding	15/5268	30/18639	0.5	1.76907744874715	0.0095196507031799	0.04758403239945
GO:0008234	cysteine-type peptidase activity	68/5268	187/18639	0.363636363636364	1.28660178090702	0.00953097893927926	0.04758403239945
GO:0008080	N-acetyltransferase activity	29/5268	69/18639	0.420289855072464	1.48705060909181	0.0096712933278553	0.0481057294048506
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	9/5268	15/18639	0.6	2.12289293849658	0.0100585247970237	0.0491221774632829
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	9/5268	15/18639	0.6	2.12289293849658	0.0100585247970237	0.0491221774632829
GO:0120283	protein serine/threonine kinase binding	9/5268	15/18639	0.6	2.12289293849658	0.0100585247970237	0.0491221774632829
GO:0141050	histone H3K deacetylase activity	9/5268	15/18639	0.6	2.12289293849658	0.0100585247970237	0.0491221774632829
GO:0141051	histone H4K deacetylase activity	9/5268	15/18639	0.6	2.12289293849658	0.0100585247970237	0.0491221774632829
GO:0008139	nuclear localization sequence binding	13/5268	25/18639	0.52	1.83984054669704	0.0103478569132158	0.0503520718639449
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	11/5268	20/18639	0.55	1.94598519362187	0.010712170847649	0.0519366261674823
GO:0071889	14-3-3 protein binding	16/5268	33/18639	0.484848484848485	1.71546904120936	0.0107942426363184	0.0521462872682577
GO:0019205	nucleobase-containing compound kinase activity	20/5268	44/18639	0.454545454545455	1.60825222613377	0.0111015586712545	0.0534386856469346
GO:0008173	RNA methyltransferase activity	28/5268	67/18639	0.417910447761194	1.47863189746031	0.0118842114854132	0.0570017715175357
GO:0046966	nuclear thyroid hormone receptor binding	14/5268	28/18639	0.5	1.76907744874715	0.0121039271587369	0.0578490184134648
GO:0043560	insulin receptor substrate binding	8/5268	13/18639	0.615384615384615	2.17732609076573	0.0124903203488519	0.0588578955386248
GO:0046974	histone H3K9 methyltransferase activity	8/5268	13/18639	0.615384615384615	2.17732609076573	0.0124903203488519	0.0588578955386248
GO:0140333	glycerophospholipid flippase activity	8/5268	13/18639	0.615384615384615	2.17732609076573	0.0124903203488519	0.0588578955386248
GO:0140852	histone ubiquitin ligase activity	8/5268	13/18639	0.615384615384615	2.17732609076573	0.0124903203488519	0.0588578955386248
GO:0004540	RNA nuclease activity	46/5268	121/18639	0.380165289256198	1.34508368003916	0.0125970657909576	0.0591533543960002
GO:0004722	protein serine/threonine phosphatase activity	40/5268	103/18639	0.388349514563107	1.37404073689099	0.0130089192815712	0.0608744898785717
GO:0003887	DNA-directed DNA polymerase activity	12/5268	23/18639	0.521739130434783	1.84599385956225	0.0131805666064548	0.0610396584567888
GO:0042171	lysophosphatidic acid acyltransferase activity	12/5268	23/18639	0.521739130434783	1.84599385956225	0.0131805666064548	0.0610396584567888
GO:0071617	lysophospholipid acyltransferase activity	12/5268	23/18639	0.521739130434783	1.84599385956225	0.0131805666064548	0.0610396584567888
GO:0070064	proline-rich region binding	10/5268	18/18639	0.555555555555556	1.96564160971906	0.0135981287595201	0.0627569997389534
GO:0070325	lipoprotein particle receptor binding	15/5268	31/18639	0.483870967741935	1.71201043427144	0.0136990824211715	0.0630063962042238
GO:0004713	protein tyrosine kinase activity	52/5268	140/18639	0.371428571428571	1.31417181906931	0.0138251819789905	0.0633693494804921
GO:0051539	4 iron, 4 sulfur cluster binding	20/5268	45/18639	0.444444444444444	1.57251328777525	0.0147702136169388	0.0674707377127511
GO:0005548	phospholipid transporter activity	28/5268	68/18639	0.411764705882353	1.45688731073295	0.0148612654202994	0.0676565405405494
GO:0015035	protein-disulfide reductase activity	16/5268	34/18639	0.470588235294118	1.66501406940908	0.0151289896312802	0.0683457482172045
GO:0031491	nucleosome binding	30/5268	74/18639	0.405405405405405	1.4343871206058	0.0152669926053657	0.0683457482172045
GO:0002162	dystroglycan binding	7/5268	11/18639	0.636363636363636	2.25155311658729	0.0153964537998664	0.0683457482172045
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	7/5268	11/18639	0.636363636363636	2.25155311658729	0.0153964537998664	0.0683457482172045
GO:0043522	leucine zipper domain binding	7/5268	11/18639	0.636363636363636	2.25155311658729	0.0153964537998664	0.0683457482172045
GO:0140031	phosphorylation-dependent protein binding	7/5268	11/18639	0.636363636363636	2.25155311658729	0.0153964537998664	0.0683457482172045
GO:0050681	nuclear androgen receptor binding	13/5268	26/18639	0.5	1.76907744874715	0.0154197778926381	0.0683457482172045
GO:0070006	metalloaminopeptidase activity	13/5268	26/18639	0.5	1.76907744874715	0.0154197778926381	0.0683457482172045
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	33/5268	83/18639	0.397590361445783	1.40673628454593	0.0156012400943952	0.0689225837064892
GO:0005516	calmodulin binding	73/5268	207/18639	0.352657004830918	1.24775510877819	0.016305179517163	0.0717962494804916
GO:0019213	deacetylase activity	17/5268	37/18639	0.459459459459459	1.62563873668657	0.0163975198215346	0.0719668925500687
GO:1901981	phosphatidylinositol phosphate binding	66/5268	185/18639	0.356756756756757	1.2622606661331	0.0165431951059929	0.0723697427600926
GO:0009931	calcium-dependent protein serine/threonine kinase activity	11/5268	21/18639	0.523809523809524	1.85331923202083	0.0168266824152931	0.0731334449311931
GO:0140312	cargo adaptor activity	11/5268	21/18639	0.523809523809524	1.85331923202083	0.0168266824152931	0.0731334449311931
GO:0043023	ribosomal large subunit binding	9/5268	16/18639	0.5625	1.99021212984055	0.017284410869572	0.0746397549769622
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	9/5268	16/18639	0.5625	1.99021212984055	0.017284410869572	0.0746397549769622
GO:0004712	protein serine/threonine/tyrosine kinase activity	19/5268	43/18639	0.441860465116279	1.56337076866027	0.0184859347769847	0.0795724692483669
GO:0140767	enzyme-substrate adaptor activity	51/5268	139/18639	0.366906474820144	1.29817194080726	0.0187426918141444	0.0804199204677187
GO:0051117	ATPase binding	33/5268	84/18639	0.392857142857143	1.38998942401562	0.0188725450502594	0.080719197460186
GO:0070717	poly-purine tract binding	15/5268	32/18639	0.46875	1.65851010820046	0.0191689171172134	0.0817265259949764
GO:0030159	signaling receptor complex adaptor activity	22/5268	52/18639	0.423076923076923	1.49691168740144	0.0206628708459294	0.0876814105560703
GO:0034061	DNA polymerase activity	16/5268	35/18639	0.457142857142857	1.61744223885454	0.0206962078527731	0.0876814105560703
GO:0017124	SH3 domain binding	43/5268	115/18639	0.373913043478261	1.32296226601961	0.0208894215212704	0.0882216764247365
GO:0140036	ubiquitin-modified protein reader activity	10/5268	19/18639	0.526315789473684	1.8621867881549	0.0215381589493955	0.0903856096354523
GO:1990380	K48-linked deubiquitinase activity	10/5268	19/18639	0.526315789473684	1.8621867881549	0.0215381589493955	0.0903856096354523
GO:0017116	single-stranded DNA helicase activity	24/5268	58/18639	0.413793103448276	1.46406409551488	0.0216037086321521	0.0903856096354523
GO:0098847	sequence-specific single stranded DNA binding	8/5268	14/18639	0.571428571428571	2.02180279856817	0.0219979964764404	0.09174940766416
GO:0008320	protein transmembrane transporter activity	13/5268	27/18639	0.481481481481481	1.70355606175652	0.0221797180708593	0.0919363005221113
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	13/5268	27/18639	0.481481481481481	1.70355606175652	0.0221797180708593	0.0919363005221113
GO:0016410	N-acyltransferase activity	36/5268	94/18639	0.382978723404255	1.35503804584888	0.0223243539266052	0.0922510994567101
GO:0031490	chromatin DNA binding	47/5268	128/18639	0.3671875	1.29916625142369	0.0229598791865698	0.0945862507593964
GO:0008187	poly-pyrimidine tract binding	14/5268	30/18639	0.466666666666667	1.65113895216401	0.0243226664702346	0.0998940093869269
GO:0008093	cytoskeletal anchor activity	11/5268	22/18639	0.5	1.76907744874715	0.0252037943507668	0.103197243332561
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	34/5268	89/18639	0.382022471910112	1.35165467994164	0.0268437731800525	0.109246022366092
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	34/5268	89/18639	0.382022471910112	1.35165467994164	0.0268437731800525	0.109246022366092
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	27/5268	68/18639	0.397058823529412	1.40485562106392	0.0274204177343978	0.109734919384838
GO:0032934	sterol binding	27/5268	68/18639	0.397058823529412	1.40485562106392	0.0274204177343978	0.109734919384838
GO:0004659	prenyltransferase activity	9/5268	17/18639	0.529411764705882	1.87314082808522	0.0276551074784467	0.109734919384838
GO:0005092	GDP-dissociation inhibitor activity	9/5268	17/18639	0.529411764705882	1.87314082808522	0.0276551074784467	0.109734919384838
GO:0008429	phosphatidylethanolamine binding	9/5268	17/18639	0.529411764705882	1.87314082808522	0.0276551074784467	0.109734919384838
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	16/5268	36/18639	0.444444444444444	1.57251328777525	0.0276884472079335	0.109734919384838
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	16/5268	36/18639	0.444444444444444	1.57251328777525	0.0276884472079335	0.109734919384838
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	16/5268	36/18639	0.444444444444444	1.57251328777525	0.0276884472079335	0.109734919384838
GO:0000340	RNA 7-methylguanosine cap binding	7/5268	12/18639	0.583333333333333	2.06392369020501	0.028026118651526	0.109734919384838
GO:0017166	vinculin binding	7/5268	12/18639	0.583333333333333	2.06392369020501	0.028026118651526	0.109734919384838
GO:0043047	single-stranded telomeric DNA binding	7/5268	12/18639	0.583333333333333	2.06392369020501	0.028026118651526	0.109734919384838
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	7/5268	12/18639	0.583333333333333	2.06392369020501	0.028026118651526	0.109734919384838
GO:0141221	histone deacetylase activity, hydrolytic mechanism	7/5268	12/18639	0.583333333333333	2.06392369020501	0.028026118651526	0.109734919384838
GO:0004518	nuclease activity	72/5268	209/18639	0.344497607655502	1.21888589770139	0.0290880030646612	0.11356159336
GO:0019789	SUMO transferase activity	13/5268	28/18639	0.464285714285714	1.64271477383664	0.0309120701946986	0.119305344003702
GO:0046875	ephrin receptor binding	13/5268	28/18639	0.464285714285714	1.64271477383664	0.0309120701946986	0.119305344003702
GO:0097718	disordered domain specific binding	13/5268	28/18639	0.464285714285714	1.64271477383664	0.0309120701946986	0.119305344003702
GO:0140303	intramembrane lipid transporter activity	19/5268	45/18639	0.422222222222222	1.49388762338648	0.0309145641945556	0.119305344003702
GO:0140793	histone H2AXY142 phosphatase activity	34/5268	90/18639	0.377777777777778	1.33663629460896	0.0317108599918815	0.121557143549798
GO:0030742	GTP-dependent protein binding	10/5268	20/18639	0.5	1.76907744874715	0.0323641470511419	0.121557143549798
GO:0043024	ribosomal small subunit binding	10/5268	20/18639	0.5	1.76907744874715	0.0323641470511419	0.121557143549798
GO:0033192	calmodulin-dependent protein phosphatase activity	31/5268	81/18639	0.382716049382716	1.35410866447313	0.0325753325622535	0.121557143549798
GO:0140791	histone H2AXS140 phosphatase activity	31/5268	81/18639	0.382716049382716	1.35410866447313	0.0325753325622535	0.121557143549798
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	31/5268	81/18639	0.382716049382716	1.35410866447313	0.0325753325622535	0.121557143549798
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	31/5268	81/18639	0.382716049382716	1.35410866447313	0.0325753325622535	0.121557143549798
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	31/5268	81/18639	0.382716049382716	1.35410866447313	0.0325753325622535	0.121557143549798
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	31/5268	81/18639	0.382716049382716	1.35410866447313	0.0325753325622535	0.121557143549798
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	31/5268	81/18639	0.382716049382716	1.35410866447313	0.0325753325622535	0.121557143549798
GO:1990439	MAP kinase serine/threonine phosphatase activity	31/5268	81/18639	0.382716049382716	1.35410866447313	0.0325753325622535	0.121557143549798
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	22/5268	54/18639	0.407407407407407	1.44147051379398	0.03258419335661	0.121557143549798
GO:0015932	nucleobase-containing compound transmembrane transporter activity	23/5268	57/18639	0.403508771929825	1.42767653758542	0.0328883444217773	0.122351929524784
GO:0030332	cyclin binding	15/5268	34/18639	0.441176470588235	1.56095069007102	0.034846883217969	0.12758249976659
GO:0052866	phosphatidylinositol phosphate phosphatase activity	15/5268	34/18639	0.441176470588235	1.56095069007102	0.034846883217969	0.12758249976659
GO:0042809	nuclear vitamin D receptor binding	8/5268	15/18639	0.533333333333333	1.8870159453303	0.0356431069672025	0.12758249976659
GO:0001094	TFIID-class transcription factor complex binding	6/5268	10/18639	0.6	2.12289293849658	0.0357193000091124	0.12758249976659
GO:0005528	FK506 binding	6/5268	10/18639	0.6	2.12289293849658	0.0357193000091124	0.12758249976659
GO:0016303	1-phosphatidylinositol-3-kinase activity	6/5268	10/18639	0.6	2.12289293849658	0.0357193000091124	0.12758249976659
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	6/5268	10/18639	0.6	2.12289293849658	0.0357193000091124	0.12758249976659
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	6/5268	10/18639	0.6	2.12289293849658	0.0357193000091124	0.12758249976659
GO:0045322	unmethylated CpG binding	6/5268	10/18639	0.6	2.12289293849658	0.0357193000091124	0.12758249976659
GO:0051864	histone H3K36 demethylase activity	6/5268	10/18639	0.6	2.12289293849658	0.0357193000091124	0.12758249976659
GO:0051880	G-quadruplex DNA binding	6/5268	10/18639	0.6	2.12289293849658	0.0357193000091124	0.12758249976659
GO:0140999	histone H3K4 trimethyltransferase activity	6/5268	10/18639	0.6	2.12289293849658	0.0357193000091124	0.12758249976659
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	6/5268	10/18639	0.6	2.12289293849658	0.0357193000091124	0.12758249976659
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	6/5268	10/18639	0.6	2.12289293849658	0.0357193000091124	0.12758249976659
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	6/5268	10/18639	0.6	2.12289293849658	0.0357193000091124	0.12758249976659
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	11/5268	23/18639	0.478260869565217	1.69216103793206	0.0362250864497197	0.128027081847299
GO:0005158	insulin receptor binding	11/5268	23/18639	0.478260869565217	1.69216103793206	0.0362250864497197	0.128027081847299
GO:0017134	fibroblast growth factor binding	11/5268	23/18639	0.478260869565217	1.69216103793206	0.0362250864497197	0.128027081847299
GO:0070577	lysine-acetylated histone binding	11/5268	23/18639	0.478260869565217	1.69216103793206	0.0362250864497197	0.128027081847299
GO:0004177	aminopeptidase activity	17/5268	40/18639	0.425	1.50371583143508	0.0374503103786839	0.131664311095739
GO:0030331	nuclear estrogen receptor binding	17/5268	40/18639	0.425	1.50371583143508	0.0374503103786839	0.131664311095739
GO:0004197	cysteine-type endopeptidase activity	33/5268	88/18639	0.375	1.32680808656036	0.0376953872730265	0.132179908897323
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	31/5268	82/18639	0.378048780487805	1.33759514417468	0.0385629035969833	0.134519427352594
GO:0033549	MAP kinase phosphatase activity	31/5268	82/18639	0.378048780487805	1.33759514417468	0.0385629035969833	0.134519427352594
GO:0035254	glutamate receptor binding	20/5268	49/18639	0.408163265306122	1.44414485612012	0.0395906886287582	0.13774687779384
GO:0140313	molecular sequestering activity	22/5268	55/18639	0.4	1.41526195899772	0.0401885370504227	0.139465646663353
GO:0017075	syntaxin-1 binding	9/5268	18/18639	0.5	1.76907744874715	0.0417120861973733	0.144008564943631
GO:0035615	clathrin adaptor activity	9/5268	18/18639	0.5	1.76907744874715	0.0417120861973733	0.144008564943631
GO:0001217	DNA-binding transcription repressor activity	92/5268	278/18639	0.330935251798561	1.17090018190459	0.0429095082317252	0.147762742449249
GO:0002020	protease binding	48/5268	136/18639	0.352941176470588	1.24876055205681	0.0437714542580224	0.150345429842773
GO:0022884	macromolecule transmembrane transporter activity	14/5268	32/18639	0.4375	1.54794276765376	0.0438846207185984	0.150349606186423
GO:0005154	epidermal growth factor receptor binding	15/5268	35/18639	0.428571428571429	1.51635209892613	0.0454598897418657	0.154955918587121
GO:0140566	histone reader activity	15/5268	35/18639	0.428571428571429	1.51635209892613	0.0454598897418657	0.154955918587121
GO:0005338	nucleotide-sugar transmembrane transporter activity	7/5268	13/18639	0.538461538461538	1.90516032942001	0.0461512166713125	0.156914136682463
GO:0070182	DNA polymerase binding	10/5268	21/18639	0.476190476190476	1.68483566547348	0.0464891149019136	0.157663841700177
GO:0001727	lipid kinase activity	17/5268	41/18639	0.414634146341463	1.46703983554642	0.047585477700674	0.160168663037607
GO:0008137	NADH dehydrogenase (ubiquinone) activity	17/5268	41/18639	0.414634146341463	1.46703983554642	0.047585477700674	0.160168663037607
GO:0140318	protein transporter activity	17/5268	41/18639	0.414634146341463	1.46703983554642	0.047585477700674	0.160168663037607
GO:0001046	core promoter sequence-specific DNA binding	18/5268	44/18639	0.409090909090909	1.4474270035204	0.0482414670970216	0.160764988365509
GO:0001223	transcription coactivator binding	18/5268	44/18639	0.409090909090909	1.4474270035204	0.0482414670970216	0.160764988365509
GO:0003954	NADH dehydrogenase activity	18/5268	44/18639	0.409090909090909	1.4474270035204	0.0482414670970216	0.160764988365509
GO:0043014	alpha-tubulin binding	18/5268	44/18639	0.409090909090909	1.4474270035204	0.0482414670970216	0.160764988365509
GO:0043495	protein-membrane adaptor activity	19/5268	47/18639	0.404255319148936	1.43031793728493	0.0486820347618871	0.161831615557461
GO:0003774	cytoskeletal motor activity	53/5268	153/18639	0.34640522875817	1.22563535664835	0.0495810912000481	0.164413346868308
GO:0001091	RNA polymerase II general transcription initiation factor binding	11/5268	24/18639	0.458333333333333	1.62165432801822	0.0502178848136083	0.164494193426039
GO:0035035	histone acetyltransferase binding	11/5268	24/18639	0.458333333333333	1.62165432801822	0.0502178848136083	0.164494193426039
GO:0048027	mRNA 5'-UTR binding	11/5268	24/18639	0.458333333333333	1.62165432801822	0.0502178848136083	0.164494193426039
GO:0070840	dynein complex binding	11/5268	24/18639	0.458333333333333	1.62165432801822	0.0502178848136083	0.164494193426039
GO:0140033	acetylation-dependent protein binding	11/5268	24/18639	0.458333333333333	1.62165432801822	0.0502178848136083	0.164494193426039
GO:0035401	histone H3Y41 kinase activity	41/5268	115/18639	0.356521739130435	1.26142913736753	0.0506120347548841	0.164980491931576
GO:0140801	histone H2AXY142 kinase activity	41/5268	115/18639	0.356521739130435	1.26142913736753	0.0506120347548841	0.164980491931576
GO:0042578	phosphoric ester hydrolase activity	117/5268	363/18639	0.322314049586777	1.14039703307668	0.0521725078052103	0.169655394630502
GO:0017018	myosin phosphatase activity	31/5268	84/18639	0.369047619047619	1.30574764074195	0.0529583261288939	0.171794763263538
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	12/5268	27/18639	0.444444444444444	1.57251328777525	0.0531018142902085	0.171845148413855
GO:0001618	virus receptor activity	30/5268	81/18639	0.37037037037037	1.31042773981271	0.0537890292523102	0.173089311494202
GO:0005159	insulin-like growth factor receptor binding	8/5268	16/18639	0.5	1.76907744874715	0.054001803064833	0.173089311494202
GO:0005521	lamin binding	8/5268	16/18639	0.5	1.76907744874715	0.054001803064833	0.173089311494202
GO:0008296	3'-5'-DNA exonuclease activity	8/5268	16/18639	0.5	1.76907744874715	0.054001803064833	0.173089311494202
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	43/5268	122/18639	0.352459016393443	1.24705459501848	0.0550726035633778	0.176101206156229
GO:0015215	nucleotide transmembrane transporter activity	13/5268	30/18639	0.433333333333333	1.53320045558087	0.055304027168351	0.176421160301889
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	88/5268	268/18639	0.328358208955224	1.16178220514738	0.0556412558453271	0.177076318957996
GO:0016853	isomerase activity	61/5268	180/18639	0.338888888888889	1.19904138192863	0.056501645498645	0.179389385117448
GO:0019209	kinase activator activity	51/5268	148/18639	0.344594594594595	1.21922905251493	0.0580096494125355	0.183742828209989
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	16/5268	39/18639	0.41025641025641	1.45155072717715	0.0589854181877124	0.184299814755841
GO:0016504	peptidase activator activity	22/5268	57/18639	0.385964912280702	1.36560364464692	0.0591554069542363	0.184299814755841
GO:0003925	G protein activity	21/5268	54/18639	0.388888888888889	1.37594912680334	0.059518961328691	0.184299814755841
GO:0015485	cholesterol binding	21/5268	54/18639	0.388888888888889	1.37594912680334	0.059518961328691	0.184299814755841
GO:0004715	non-membrane spanning protein tyrosine kinase activity	18/5268	45/18639	0.4	1.41526195899772	0.0597927356986658	0.184299814755841
GO:0140693	molecular condensate scaffold activity	19/5268	48/18639	0.395833333333333	1.40051964692483	0.0598640419671541	0.184299814755841
GO:0050145	nucleoside monophosphate kinase activity	9/5268	19/18639	0.473684210526316	1.67596810933941	0.0598686207205534	0.184299814755841
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	6/5268	11/18639	0.545454545454545	1.92990267136053	0.0601067154602073	0.184299814755841
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	6/5268	11/18639	0.545454545454545	1.92990267136053	0.0601067154602073	0.184299814755841
GO:0019107	myristoyltransferase activity	6/5268	11/18639	0.545454545454545	1.92990267136053	0.0601067154602073	0.184299814755841
GO:0034713	type I transforming growth factor beta receptor binding	6/5268	11/18639	0.545454545454545	1.92990267136053	0.0601067154602073	0.184299814755841
GO:0047676	arachidonate-CoA ligase activity	6/5268	11/18639	0.545454545454545	1.92990267136053	0.0601067154602073	0.184299814755841
GO:0140537	transcription regulator activator activity	6/5268	11/18639	0.545454545454545	1.92990267136053	0.0601067154602073	0.184299814755841
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	6/5268	11/18639	0.545454545454545	1.92990267136053	0.0601067154602073	0.184299814755841
GO:0030295	protein kinase activator activity	48/5268	139/18639	0.345323741007194	1.22180888546566	0.0622099643557405	0.190314310090568
GO:0140272	exogenous protein binding	30/5268	82/18639	0.365853658536585	1.29444691371743	0.0625733325149989	0.190990876290099
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	10/5268	22/18639	0.454545454545455	1.60825222613377	0.0642268820278692	0.195150910776987
GO:0061133	endopeptidase activator activity	10/5268	22/18639	0.454545454545455	1.60825222613377	0.0642268820278692	0.195150910776987
GO:0043539	protein serine/threonine kinase activator activity	27/5268	73/18639	0.36986301369863	1.30863263331981	0.0658396436669848	0.199599642087496
GO:0004709	MAP kinase kinase kinase activity	11/5268	25/18639	0.44	1.55678815489749	0.0674312657777913	0.203506044808031
GO:0042974	nuclear retinoic acid receptor binding	11/5268	25/18639	0.44	1.55678815489749	0.0674312657777913	0.203506044808031
GO:0005161	platelet-derived growth factor receptor binding	7/5268	14/18639	0.5	1.76907744874715	0.0703044368661845	0.210286990448298
GO:0005545	1-phosphatidylinositol binding	7/5268	14/18639	0.5	1.76907744874715	0.0703044368661845	0.210286990448298
GO:0030983	mismatched DNA binding	7/5268	14/18639	0.5	1.76907744874715	0.0703044368661845	0.210286990448298
GO:0070742	C2H2 zinc finger domain binding	7/5268	14/18639	0.5	1.76907744874715	0.0703044368661845	0.210286990448298
GO:0016411	acylglycerol O-acyltransferase activity	13/5268	31/18639	0.419354838709677	1.48374237636858	0.0713608520616655	0.212319805316937
GO:0070273	phosphatidylinositol-4-phosphate binding	13/5268	31/18639	0.419354838709677	1.48374237636858	0.0713608520616655	0.212319805316937
GO:0008374	O-acyltransferase activity	21/5268	55/18639	0.381818181818182	1.35093186995237	0.0714583410299744	0.212319805316937
GO:0000049	tRNA binding	29/5268	80/18639	0.3625	1.28258115034169	0.073765024099472	0.218689685133755
GO:0031489	myosin V binding	8/5268	17/18639	0.470588235294118	1.66501406940908	0.0774210880305097	0.228018686896874
GO:0046965	nuclear retinoid X receptor binding	8/5268	17/18639	0.470588235294118	1.66501406940908	0.0774210880305097	0.228018686896874
GO:1990226	histone methyltransferase binding	8/5268	17/18639	0.470588235294118	1.66501406940908	0.0774210880305097	0.228018686896874
GO:0031418	L-ascorbic acid binding	9/5268	20/18639	0.45	1.59216970387244	0.0823722809955265	0.242069963625803
GO:0000295	adenine nucleotide transmembrane transporter activity	10/5268	23/18639	0.434782608695652	1.53832821630187	0.0857667247802918	0.250947083616409
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	10/5268	23/18639	0.434782608695652	1.53832821630187	0.0857667247802918	0.250947083616409
GO:0016860	intramolecular oxidoreductase activity	20/5268	53/18639	0.377358490566038	1.33515279150728	0.0861406536821939	0.250947717776977
GO:0051018	protein kinase A binding	20/5268	53/18639	0.377358490566038	1.33515279150728	0.0861406536821939	0.250947717776977
GO:0005112	Notch binding	11/5268	26/18639	0.423076923076923	1.49691168740144	0.0880178430438807	0.254758541396405
GO:0005160	transforming growth factor beta receptor binding	11/5268	26/18639	0.423076923076923	1.49691168740144	0.0880178430438807	0.254758541396405
GO:0034237	protein kinase A regulatory subunit binding	11/5268	26/18639	0.423076923076923	1.49691168740144	0.0880178430438807	0.254758541396405
GO:0106222	lncRNA binding	12/5268	29/18639	0.413793103448276	1.46406409551488	0.0894137822413746	0.258242386129389
GO:0043015	gamma-tubulin binding	14/5268	35/18639	0.4	1.41526195899772	0.0904079452235771	0.259554633914293
GO:0003995	acyl-CoA dehydrogenase activity	6/5268	12/18639	0.5	1.76907744874715	0.0921873122688887	0.259554633914293
GO:0004000	adenosine deaminase activity	6/5268	12/18639	0.5	1.76907744874715	0.0921873122688887	0.259554633914293
GO:0004300	enoyl-CoA hydratase activity	6/5268	12/18639	0.5	1.76907744874715	0.0921873122688887	0.259554633914293
GO:0005078	MAP-kinase scaffold activity	6/5268	12/18639	0.5	1.76907744874715	0.0921873122688887	0.259554633914293
GO:0005527	macrolide binding	6/5268	12/18639	0.5	1.76907744874715	0.0921873122688887	0.259554633914293
GO:0031543	peptidyl-proline dioxygenase activity	6/5268	12/18639	0.5	1.76907744874715	0.0921873122688887	0.259554633914293
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	6/5268	12/18639	0.5	1.76907744874715	0.0921873122688887	0.259554633914293
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	6/5268	12/18639	0.5	1.76907744874715	0.0921873122688887	0.259554633914293
GO:0070410	co-SMAD binding	6/5268	12/18639	0.5	1.76907744874715	0.0921873122688887	0.259554633914293
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	6/5268	12/18639	0.5	1.76907744874715	0.0921873122688887	0.259554633914293
GO:1990817	poly(A) RNA polymerase activity	6/5268	12/18639	0.5	1.76907744874715	0.0921873122688887	0.259554633914293
GO:0016835	carbon-oxygen lyase activity	28/5268	79/18639	0.354430379746835	1.25402958392203	0.0994122096020621	0.279236062001709
GO:0000774	adenyl-nucleotide exchange factor activity	7/5268	15/18639	0.466666666666667	1.65113895216401	0.100633100527794	0.279236062001709
GO:0004129	cytochrome-c oxidase activity	7/5268	15/18639	0.466666666666667	1.65113895216401	0.100633100527794	0.279236062001709
GO:0031386	protein tag activity	7/5268	15/18639	0.466666666666667	1.65113895216401	0.100633100527794	0.279236062001709
GO:0051371	muscle alpha-actinin binding	7/5268	15/18639	0.466666666666667	1.65113895216401	0.100633100527794	0.279236062001709
GO:0140776	protein-containing complex destabilizing activity	7/5268	15/18639	0.466666666666667	1.65113895216401	0.100633100527794	0.279236062001709
GO:0141047	molecular tag activity	7/5268	15/18639	0.466666666666667	1.65113895216401	0.100633100527794	0.279236062001709
GO:0051287	NAD binding	20/5268	54/18639	0.37037037037037	1.31042773981271	0.101800472713666	0.281892855370008
GO:0030544	Hsp70 protein binding	19/5268	51/18639	0.372549019607843	1.31813613828219	0.103599839386094	0.286285152871449
GO:0032266	phosphatidylinositol-3-phosphate binding	18/5268	48/18639	0.375	1.32680808656036	0.105331574198063	0.290472903794659
GO:0004706	JUN kinase kinase kinase activity	8/5268	18/18639	0.444444444444444	1.57251328777525	0.105988289497019	0.290494434274483
GO:0050811	GABA receptor binding	8/5268	18/18639	0.444444444444444	1.57251328777525	0.105988289497019	0.290494434274483
GO:0070628	proteasome binding	8/5268	18/18639	0.444444444444444	1.57251328777525	0.105988289497019	0.290494434274483
GO:0050660	flavin adenine dinucleotide binding	30/5268	86/18639	0.348837209302326	1.23424008052127	0.107733382111126	0.294676032943468
GO:0016859	cis-trans isomerase activity	16/5268	42/18639	0.380952380952381	1.34786853237878	0.108480141522237	0.296115508260904
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	24/5268	67/18639	0.358208955223881	1.26739876925169	0.109000109928281	0.296931333942558
GO:0008373	sialyltransferase activity	9/5268	21/18639	0.428571428571429	1.51635209892613	0.109284655565736	0.2971038308194
GO:0050431	transforming growth factor beta binding	10/5268	24/18639	0.416666666666667	1.47423120728929	0.111158753327923	0.30064333385006
GO:0070300	phosphatidic acid binding	10/5268	24/18639	0.416666666666667	1.47423120728929	0.111158753327923	0.30064333385006
GO:0140311	protein sequestering activity	13/5268	33/18639	0.393939393939394	1.39381859598261	0.111744623891657	0.30064333385006
GO:0140416	transcription regulator inhibitor activity	13/5268	33/18639	0.393939393939394	1.39381859598261	0.111744623891657	0.30064333385006
GO:0008266	poly(U) RNA binding	11/5268	27/18639	0.407407407407407	1.44147051379398	0.112022612812031	0.30064333385006
GO:0035255	ionotropic glutamate receptor binding	11/5268	27/18639	0.407407407407407	1.44147051379398	0.112022612812031	0.30064333385006
GO:0070566	adenylyltransferase activity	12/5268	30/18639	0.4	1.41526195899772	0.112153618956724	0.30064333385006
GO:0051213	dioxygenase activity	32/5268	93/18639	0.344086021505376	1.21742964214858	0.115496001823131	0.308986315634393
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	21/5268	58/18639	0.362068965517241	1.28105608357552	0.116571544865353	0.311243707264749
GO:0140101	catalytic activity, acting on a tRNA	46/5268	139/18639	0.330935251798561	1.17090018190459	0.120893780424637	0.318874683830125
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	5/5268	10/18639	0.5	1.76907744874715	0.122041390535134	0.318874683830125
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	5/5268	10/18639	0.5	1.76907744874715	0.122041390535134	0.318874683830125
GO:0005522	profilin binding	5/5268	10/18639	0.5	1.76907744874715	0.122041390535134	0.318874683830125
GO:0015924	mannosyl-oligosaccharide mannosidase activity	5/5268	10/18639	0.5	1.76907744874715	0.122041390535134	0.318874683830125
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	5/5268	10/18639	0.5	1.76907744874715	0.122041390535134	0.318874683830125
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	5/5268	10/18639	0.5	1.76907744874715	0.122041390535134	0.318874683830125
GO:0030957	Tat protein binding	5/5268	10/18639	0.5	1.76907744874715	0.122041390535134	0.318874683830125
GO:0047429	nucleoside triphosphate diphosphatase activity	5/5268	10/18639	0.5	1.76907744874715	0.122041390535134	0.318874683830125
GO:0098505	G-rich strand telomeric DNA binding	5/5268	10/18639	0.5	1.76907744874715	0.122041390535134	0.318874683830125
GO:1905394	retromer complex binding	5/5268	10/18639	0.5	1.76907744874715	0.122041390535134	0.318874683830125
GO:0030145	manganese ion binding	24/5268	68/18639	0.352941176470588	1.24876055205681	0.125085163027693	0.326192959118818
GO:0120013	lipid transfer activity	23/5268	65/18639	0.353846153846154	1.25196250219029	0.128239595929223	0.333770886304161
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	6/5268	13/18639	0.461538461538462	1.63299456807429	0.131646822781097	0.340658348737983
GO:0004535	poly(A)-specific ribonuclease activity	6/5268	13/18639	0.461538461538462	1.63299456807429	0.131646822781097	0.340658348737983
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	6/5268	13/18639	0.461538461538462	1.63299456807429	0.131646822781097	0.340658348737983
GO:1990782	protein tyrosine kinase binding	39/5268	117/18639	0.333333333333333	1.17938496583144	0.132262425924567	0.341593150032104
GO:0042805	actinin binding	14/5268	37/18639	0.378378378378378	1.33876131256541	0.133986545623739	0.345381824899579
GO:0008175	tRNA methyltransferase activity	13/5268	34/18639	0.382352941176471	1.35282393139488	0.136083038710226	0.349542271552331
GO:0008142	oxysterol binding	7/5268	16/18639	0.4375	1.54794276765376	0.13690188744343	0.349542271552331
GO:0016675	oxidoreductase activity, acting on a heme group of donors	7/5268	16/18639	0.4375	1.54794276765376	0.13690188744343	0.349542271552331
GO:0017070	U6 snRNA binding	7/5268	16/18639	0.4375	1.54794276765376	0.13690188744343	0.349542271552331
GO:0140328	floppase activity	7/5268	16/18639	0.4375	1.54794276765376	0.13690188744343	0.349542271552331
GO:0004857	enzyme inhibitor activity	128/5268	416/18639	0.307692307692308	1.08866304538286	0.137505445917548	0.35041710411246
GO:0051393	alpha-actinin binding	11/5268	28/18639	0.392857142857143	1.38998942401562	0.13937928310333	0.352878057876315
GO:0051959	dynein light intermediate chain binding	11/5268	28/18639	0.392857142857143	1.38998942401562	0.13937928310333	0.352878057876315
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	11/5268	28/18639	0.392857142857143	1.38998942401562	0.13937928310333	0.352878057876315
GO:0005346	purine ribonucleotide transmembrane transporter activity	8/5268	19/18639	0.421052631578947	1.48974943052392	0.139529866788994	0.352878057876315
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	10/5268	25/18639	0.4	1.41526195899772	0.140310411694678	0.352878057876315
GO:0017025	TBP-class protein binding	10/5268	25/18639	0.4	1.41526195899772	0.140310411694678	0.352878057876315
GO:0017056	structural constituent of nuclear pore	10/5268	25/18639	0.4	1.41526195899772	0.140310411694678	0.352878057876315
GO:1901505	carbohydrate derivative transmembrane transporter activity	19/5268	53/18639	0.358490566037736	1.26839515193192	0.141589957648463	0.355430491816608
GO:0001784	phosphotyrosine residue binding	17/5268	47/18639	0.361702127659574	1.27975815441283	0.148650633483858	0.372458583523921
GO:0016248	channel inhibitor activity	16/5268	44/18639	0.363636363636364	1.28660178090702	0.152248141356643	0.380665751722307
GO:0051536	iron-sulfur cluster binding	26/5268	76/18639	0.342105263157895	1.21042141230068	0.152493056162771	0.380665751722307
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	21/5268	60/18639	0.35	1.23835421412301	0.15453196343721	0.384326716474394
GO:0098531	ligand-modulated transcription factor activity	21/5268	60/18639	0.35	1.23835421412301	0.15453196343721	0.384326716474394
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	15/5268	41/18639	0.365853658536585	1.29444691371743	0.155869016995868	0.386935471026711
GO:0097110	scaffold protein binding	24/5268	70/18639	0.342857142857143	1.2130816791409	0.161303613338523	0.39947512342363
GO:0030165	PDZ domain binding	28/5268	83/18639	0.337349397590361	1.19359442325109	0.161515258390939	0.39947512342363
GO:0009055	electron transfer activity	38/5268	116/18639	0.327586206896552	1.15905074228262	0.164487391911492	0.406078248781495
GO:0019838	growth factor binding	44/5268	136/18639	0.323529411764706	1.14469717271875	0.16637467429581	0.409983830420685
GO:0043236	laminin binding	11/5268	29/18639	0.379310344827586	1.34205875422198	0.169913755852303	0.413408852352781
GO:0051540	metal cluster binding	26/5268	77/18639	0.337662337662338	1.19470165369938	0.171058748410283	0.413408852352781
GO:0004529	DNA exonuclease activity	10/5268	26/18639	0.384615384615385	1.36082880672858	0.172993267101426	0.413408852352781
GO:0008143	poly(A) binding	10/5268	26/18639	0.384615384615385	1.36082880672858	0.172993267101426	0.413408852352781
GO:0015216	purine nucleotide transmembrane transporter activity	10/5268	26/18639	0.384615384615385	1.36082880672858	0.172993267101426	0.413408852352781
GO:0030507	spectrin binding	10/5268	26/18639	0.384615384615385	1.36082880672858	0.172993267101426	0.413408852352781
GO:0052742	phosphatidylinositol kinase activity	10/5268	26/18639	0.384615384615385	1.36082880672858	0.172993267101426	0.413408852352781
GO:0120014	phospholipid transfer activity	10/5268	26/18639	0.384615384615385	1.36082880672858	0.172993267101426	0.413408852352781
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	5/5268	11/18639	0.454545454545455	1.60825222613377	0.173653619764239	0.413408852352781
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	5/5268	11/18639	0.454545454545455	1.60825222613377	0.173653619764239	0.413408852352781
GO:0004143	ATP-dependent diacylglycerol kinase activity	5/5268	11/18639	0.454545454545455	1.60825222613377	0.173653619764239	0.413408852352781
GO:0019206	nucleoside kinase activity	5/5268	11/18639	0.454545454545455	1.60825222613377	0.173653619764239	0.413408852352781
GO:0032404	mismatch repair complex binding	5/5268	11/18639	0.454545454545455	1.60825222613377	0.173653619764239	0.413408852352781
GO:0035252	UDP-xylosyltransferase activity	5/5268	11/18639	0.454545454545455	1.60825222613377	0.173653619764239	0.413408852352781
GO:0042285	xylosyltransferase activity	5/5268	11/18639	0.454545454545455	1.60825222613377	0.173653619764239	0.413408852352781
GO:0042608	T cell receptor binding	5/5268	11/18639	0.454545454545455	1.60825222613377	0.173653619764239	0.413408852352781
GO:0097493	structural molecule activity conferring elasticity	5/5268	11/18639	0.454545454545455	1.60825222613377	0.173653619764239	0.413408852352781
GO:0180030	inositol phosphate kinase activity	5/5268	11/18639	0.454545454545455	1.60825222613377	0.173653619764239	0.413408852352781
GO:0141110	transporter inhibitor activity	16/5268	45/18639	0.355555555555556	1.2580106302202	0.17722945896883	0.413408852352781
GO:0052745	inositol phosphate phosphatase activity	8/5268	20/18639	0.4	1.41526195899772	0.177634923984639	0.413408852352781
GO:0004705	JUN kinase activity	6/5268	14/18639	0.428571428571429	1.51635209892613	0.177653612217281	0.413408852352781
GO:0005347	ATP transmembrane transporter activity	6/5268	14/18639	0.428571428571429	1.51635209892613	0.177653612217281	0.413408852352781
GO:0032036	myosin heavy chain binding	6/5268	14/18639	0.428571428571429	1.51635209892613	0.177653612217281	0.413408852352781
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	6/5268	14/18639	0.428571428571429	1.51635209892613	0.177653612217281	0.413408852352781
GO:0044548	S100 protein binding	6/5268	14/18639	0.428571428571429	1.51635209892613	0.177653612217281	0.413408852352781
GO:0046030	inositol trisphosphate phosphatase activity	6/5268	14/18639	0.428571428571429	1.51635209892613	0.177653612217281	0.413408852352781
GO:0061665	SUMO ligase activity	6/5268	14/18639	0.428571428571429	1.51635209892613	0.177653612217281	0.413408852352781
GO:0071933	Arp2/3 complex binding	6/5268	14/18639	0.428571428571429	1.51635209892613	0.177653612217281	0.413408852352781
GO:1990825	sequence-specific mRNA binding	6/5268	14/18639	0.428571428571429	1.51635209892613	0.177653612217281	0.413408852352781
GO:0016018	cyclosporin A binding	7/5268	17/18639	0.411764705882353	1.45688731073295	0.178538447032474	0.413408852352781
GO:0017110	nucleoside diphosphate phosphatase activity	7/5268	17/18639	0.411764705882353	1.45688731073295	0.178538447032474	0.413408852352781
GO:0030169	low-density lipoprotein particle binding	7/5268	17/18639	0.411764705882353	1.45688731073295	0.178538447032474	0.413408852352781
GO:0038191	neuropilin binding	7/5268	17/18639	0.411764705882353	1.45688731073295	0.178538447032474	0.413408852352781
GO:0051787	misfolded protein binding	7/5268	17/18639	0.411764705882353	1.45688731073295	0.178538447032474	0.413408852352781
GO:0070403	NAD+ binding	7/5268	17/18639	0.411764705882353	1.45688731073295	0.178538447032474	0.413408852352781
GO:0008307	structural constituent of muscle	15/5268	42/18639	0.357142857142857	1.26362674910511	0.182196170036774	0.420428619174204
GO:0019894	kinesin binding	15/5268	42/18639	0.357142857142857	1.26362674910511	0.182196170036774	0.420428619174204
GO:0055106	ubiquitin-protein transferase regulator activity	13/5268	36/18639	0.361111111111111	1.27766704631739	0.192543042506021	0.44280261580053
GO:0160215	deacylase activity	22/5268	65/18639	0.338461538461538	1.19752934992115	0.192551547004847	0.44280261580053
GO:0016651	oxidoreductase activity, acting on NAD(P)H	29/5268	88/18639	0.329545454545455	1.16598286394699	0.193390933005768	0.443972688934609
GO:0001965	G-protein alpha-subunit binding	11/5268	30/18639	0.366666666666667	1.29732346241458	0.203353835107638	0.465395345837502
GO:0016757	glycosyltransferase activity	82/5268	267/18639	0.307116104868914	1.08662435054132	0.203415538351909	0.465395345837502
GO:0030276	clathrin binding	16/5268	46/18639	0.347826086956522	1.2306625730415	0.20411722434329	0.466206517505168
GO:0004879	nuclear receptor activity	20/5268	59/18639	0.338983050847458	1.19937454152349	0.204728200618874	0.466808104297364
GO:0023026	MHC class II protein complex binding	10/5268	27/18639	0.37037037037037	1.31042773981271	0.208858357859894	0.475418262043793
GO:0008200	ion channel inhibitor activity	15/5268	43/18639	0.348837209302326	1.23424008052127	0.2105321540808	0.478417399205609
GO:0044325	transmembrane transporter binding	43/5268	136/18639	0.316176470588235	1.11868132788423	0.217191555574625	0.491994488742574
GO:0071949	FAD binding	14/5268	40/18639	0.35	1.23835421412301	0.217239562043445	0.491994488742574
GO:0019200	carbohydrate kinase activity	8/5268	21/18639	0.380952380952381	1.34786853237878	0.219696627627041	0.496721499836895
GO:0000900	mRNA regulatory element binding translation repressor activity	7/5268	18/18639	0.388888888888889	1.37594912680334	0.224706729100491	0.503808242373889
GO:0003746	translation elongation factor activity	7/5268	18/18639	0.388888888888889	1.37594912680334	0.224706729100491	0.503808242373889
GO:0008409	5'-3' exonuclease activity	7/5268	18/18639	0.388888888888889	1.37594912680334	0.224706729100491	0.503808242373889
GO:0008525	phosphatidylcholine transporter activity	7/5268	18/18639	0.388888888888889	1.37594912680334	0.224706729100491	0.503808242373889
GO:0031690	adrenergic receptor binding	7/5268	18/18639	0.388888888888889	1.37594912680334	0.224706729100491	0.503808242373889
GO:0004521	RNA endonuclease activity	24/5268	73/18639	0.328767123287671	1.16322900739539	0.22512658742024	0.503908344842304
GO:0004467	long-chain fatty acid-CoA ligase activity	6/5268	15/18639	0.4	1.41526195899772	0.229000620010273	0.505464734284528
GO:0004559	alpha-mannosidase activity	6/5268	15/18639	0.4	1.41526195899772	0.229000620010273	0.505464734284528
GO:0005523	tropomyosin binding	6/5268	15/18639	0.4	1.41526195899772	0.229000620010273	0.505464734284528
GO:0010181	FMN binding	6/5268	15/18639	0.4	1.41526195899772	0.229000620010273	0.505464734284528
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	6/5268	15/18639	0.4	1.41526195899772	0.229000620010273	0.505464734284528
GO:0031005	filamin binding	6/5268	15/18639	0.4	1.41526195899772	0.229000620010273	0.505464734284528
GO:0045504	dynein heavy chain binding	6/5268	15/18639	0.4	1.41526195899772	0.229000620010273	0.505464734284528
GO:0005049	nuclear export signal receptor activity	5/5268	12/18639	0.416666666666667	1.47423120728929	0.231843839403775	0.505464734284528
GO:0008603	cAMP-dependent protein kinase regulator activity	5/5268	12/18639	0.416666666666667	1.47423120728929	0.231843839403775	0.505464734284528
GO:0016273	arginine N-methyltransferase activity	5/5268	12/18639	0.416666666666667	1.47423120728929	0.231843839403775	0.505464734284528
GO:0016274	protein-arginine N-methyltransferase activity	5/5268	12/18639	0.416666666666667	1.47423120728929	0.231843839403775	0.505464734284528
GO:0034452	dynactin binding	5/5268	12/18639	0.416666666666667	1.47423120728929	0.231843839403775	0.505464734284528
GO:0035197	siRNA binding	5/5268	12/18639	0.416666666666667	1.47423120728929	0.231843839403775	0.505464734284528
GO:0035251	UDP-glucosyltransferase activity	5/5268	12/18639	0.416666666666667	1.47423120728929	0.231843839403775	0.505464734284528
GO:0035497	cAMP response element binding	5/5268	12/18639	0.416666666666667	1.47423120728929	0.231843839403775	0.505464734284528
GO:1990247	N6-methyladenosine-containing RNA reader activity	5/5268	12/18639	0.416666666666667	1.47423120728929	0.231843839403775	0.505464734284528
GO:0005178	integrin binding	50/5268	161/18639	0.31055900621118	1.09880586878705	0.239262192440268	0.520512293279598
GO:0005319	lipid transporter activity	55/5268	178/18639	0.308988764044944	1.09325010877633	0.239792883288825	0.520512293279598
GO:0050840	extracellular matrix binding	22/5268	67/18639	0.328358208955224	1.16178220514738	0.239908495562227	0.520512293279598
GO:0004536	DNA nuclease activity	21/5268	64/18639	0.328125	1.16095707574032	0.247842608700439	0.536859070136597
GO:0048029	monosaccharide binding	24/5268	74/18639	0.324324324324324	1.14750969648464	0.248653303267473	0.537747804006789
GO:0017080	sodium channel regulator activity	14/5268	41/18639	0.341463414634146	1.20815045280293	0.249061326142188	0.537764245995111
GO:1902936	phosphatidylinositol bisphosphate binding	35/5268	111/18639	0.315315315315315	1.11563442713784	0.251559160802228	0.542285638775911
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	20/5268	61/18639	0.327868852459016	1.16005078606371	0.256180465624767	0.551362764958433
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	16/5268	48/18639	0.333333333333333	1.17938496583144	0.262914589989041	0.563418068713301
GO:0016879	ligase activity, forming carbon-nitrogen bonds	16/5268	48/18639	0.333333333333333	1.17938496583144	0.262914589989041	0.563418068713301
GO:0016829	lyase activity	61/5268	200/18639	0.305	1.07913724373576	0.26304030460405	0.563418068713301
GO:0008649	rRNA methyltransferase activity	8/5268	22/18639	0.363636363636364	1.28660178090702	0.264964129822916	0.565734223135415
GO:0140517	protein-RNA adaptor activity	8/5268	22/18639	0.363636363636364	1.28660178090702	0.264964129822916	0.565734223135415
GO:0042605	peptide antigen binding	15/5268	45/18639	0.333333333333333	1.17938496583144	0.272403856336563	0.578508808055192
GO:0038024	cargo receptor activity	21/5268	65/18639	0.323076923076923	1.14309619765201	0.274231524509699	0.578508808055192
GO:0003756	protein disulfide isomerase activity	7/5268	19/18639	0.368421052631579	1.30353075170843	0.274393232115531	0.578508808055192
GO:0008301	DNA binding, bending	7/5268	19/18639	0.368421052631579	1.30353075170843	0.274393232115531	0.578508808055192
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	7/5268	19/18639	0.368421052631579	1.30353075170843	0.274393232115531	0.578508808055192
GO:0046527	glucosyltransferase activity	7/5268	19/18639	0.368421052631579	1.30353075170843	0.274393232115531	0.578508808055192
GO:0070003	threonine-type peptidase activity	7/5268	19/18639	0.368421052631579	1.30353075170843	0.274393232115531	0.578508808055192
GO:0120227	acyl-CoA binding	7/5268	19/18639	0.368421052631579	1.30353075170843	0.274393232115531	0.578508808055192
GO:0008378	galactosyltransferase activity	11/5268	32/18639	0.34375	1.21624074601367	0.27746255791598	0.583149006699783
GO:0031369	translation initiation factor binding	11/5268	32/18639	0.34375	1.21624074601367	0.27746255791598	0.583149006699783
GO:0000062	fatty-acyl-CoA binding	6/5268	16/18639	0.375	1.32680808656036	0.284259859550379	0.592796570459874
GO:0003688	DNA replication origin binding	6/5268	16/18639	0.375	1.32680808656036	0.284259859550379	0.592796570459874
GO:0004707	MAP kinase activity	6/5268	16/18639	0.375	1.32680808656036	0.284259859550379	0.592796570459874
GO:0015923	mannosidase activity	6/5268	16/18639	0.375	1.32680808656036	0.284259859550379	0.592796570459874
GO:0097027	ubiquitin-protein transferase activator activity	6/5268	16/18639	0.375	1.32680808656036	0.284259859550379	0.592796570459874
GO:0035250	UDP-galactosyltransferase activity	10/5268	29/18639	0.344827586206897	1.22005341292907	0.288270521721794	0.599299242526887
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	10/5268	29/18639	0.344827586206897	1.22005341292907	0.288270521721794	0.599299242526887
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	40/5268	130/18639	0.307692307692308	1.08866304538286	0.291599278517449	0.60101694095278
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	5/5268	13/18639	0.384615384615385	1.36082880672858	0.294466974792948	0.60101694095278
GO:0005172	vascular endothelial growth factor receptor binding	5/5268	13/18639	0.384615384615385	1.36082880672858	0.294466974792948	0.60101694095278
GO:0008253	5'-nucleotidase activity	5/5268	13/18639	0.384615384615385	1.36082880672858	0.294466974792948	0.60101694095278
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	5/5268	13/18639	0.384615384615385	1.36082880672858	0.294466974792948	0.60101694095278
GO:0019104	DNA N-glycosylase activity	5/5268	13/18639	0.384615384615385	1.36082880672858	0.294466974792948	0.60101694095278
GO:0019855	calcium channel inhibitor activity	5/5268	13/18639	0.384615384615385	1.36082880672858	0.294466974792948	0.60101694095278
GO:0045159	myosin II binding	5/5268	13/18639	0.384615384615385	1.36082880672858	0.294466974792948	0.60101694095278
GO:0051011	microtubule minus-end binding	5/5268	13/18639	0.384615384615385	1.36082880672858	0.294466974792948	0.60101694095278
GO:0097157	pre-mRNA intronic binding	5/5268	13/18639	0.384615384615385	1.36082880672858	0.294466974792948	0.60101694095278
GO:0140666	annealing activity	5/5268	13/18639	0.384615384615385	1.36082880672858	0.294466974792948	0.60101694095278
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	5/5268	13/18639	0.384615384615385	1.36082880672858	0.294466974792948	0.60101694095278
GO:0004519	endonuclease activity	39/5268	127/18639	0.307086614173228	1.08652000789195	0.299654790493256	0.601991006720124
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	9/5268	26/18639	0.346153846153846	1.22474592605572	0.29992936413268	0.601991006720124
GO:0003735	structural constituent of ribosome	53/5268	175/18639	0.302857142857143	1.07155548324113	0.301076990254823	0.601991006720124
GO:0000182	rDNA binding	4/5268	10/18639	0.4	1.41526195899772	0.304694167569518	0.601991006720124
GO:0004090	carbonyl reductase (NADPH) activity	4/5268	10/18639	0.4	1.41526195899772	0.304694167569518	0.601991006720124
GO:0004382	GDP phosphatase activity	4/5268	10/18639	0.4	1.41526195899772	0.304694167569518	0.601991006720124
GO:0004445	inositol-polyphosphate 5-phosphatase activity	4/5268	10/18639	0.4	1.41526195899772	0.304694167569518	0.601991006720124
GO:0004862	cAMP-dependent protein kinase inhibitor activity	4/5268	10/18639	0.4	1.41526195899772	0.304694167569518	0.601991006720124
GO:0005381	iron ion transmembrane transporter activity	4/5268	10/18639	0.4	1.41526195899772	0.304694167569518	0.601991006720124
GO:0008190	eukaryotic initiation factor 4E binding	4/5268	10/18639	0.4	1.41526195899772	0.304694167569518	0.601991006720124
GO:0016783	sulfurtransferase activity	4/5268	10/18639	0.4	1.41526195899772	0.304694167569518	0.601991006720124
GO:0016868	intramolecular phosphotransferase activity	4/5268	10/18639	0.4	1.41526195899772	0.304694167569518	0.601991006720124
GO:0031419	cobalamin binding	4/5268	10/18639	0.4	1.41526195899772	0.304694167569518	0.601991006720124
GO:0031434	mitogen-activated protein kinase kinase binding	4/5268	10/18639	0.4	1.41526195899772	0.304694167569518	0.601991006720124
GO:0031957	very long-chain fatty acid-CoA ligase activity	4/5268	10/18639	0.4	1.41526195899772	0.304694167569518	0.601991006720124
GO:0031996	thioesterase binding	4/5268	10/18639	0.4	1.41526195899772	0.304694167569518	0.601991006720124
GO:0032395	MHC class II receptor activity	4/5268	10/18639	0.4	1.41526195899772	0.304694167569518	0.601991006720124
GO:0035256	G protein-coupled glutamate receptor binding	4/5268	10/18639	0.4	1.41526195899772	0.304694167569518	0.601991006720124
GO:0043295	glutathione binding	4/5268	10/18639	0.4	1.41526195899772	0.304694167569518	0.601991006720124
GO:0043422	protein kinase B binding	4/5268	10/18639	0.4	1.41526195899772	0.304694167569518	0.601991006720124
GO:0070513	death domain binding	4/5268	10/18639	0.4	1.41526195899772	0.304694167569518	0.601991006720124
GO:0016409	palmitoyltransferase activity	12/5268	36/18639	0.333333333333333	1.17938496583144	0.304805573022847	0.601991006720124
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	8/5268	23/18639	0.347826086956522	1.2306625730415	0.31259814386122	0.615570831679793
GO:0140102	catalytic activity, acting on a rRNA	8/5268	23/18639	0.347826086956522	1.2306625730415	0.31259814386122	0.615570831679793
GO:0048306	calcium-dependent protein binding	25/5268	80/18639	0.3125	1.10567340546697	0.314291586814541	0.617999415947186
GO:0005246	calcium channel regulator activity	17/5268	53/18639	0.320754716981132	1.13487987278119	0.315161412967256	0.618803768443018
GO:0008375	acetylglucosaminyltransferase activity	14/5268	43/18639	0.325581395348837	1.15195740848652	0.317234059422389	0.621964002633969
GO:0015297	antiporter activity	41/5268	135/18639	0.303703703703704	1.07455074664642	0.322584851514386	0.631532734087203
GO:0016505	peptidase activator activity involved in apoptotic process	7/5268	20/18639	0.35	1.23835421412301	0.326493859570626	0.637327403202545
GO:0042288	MHC class I protein binding	7/5268	20/18639	0.35	1.23835421412301	0.326493859570626	0.637327403202545
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	13/5268	40/18639	0.325	1.14990034168565	0.329866201524421	0.642791412060456
GO:0001968	fibronectin binding	10/5268	30/18639	0.333333333333333	1.17938496583144	0.330728865028872	0.642791412060456
GO:0016769	transferase activity, transferring nitrogenous groups	10/5268	30/18639	0.333333333333333	1.17938496583144	0.330728865028872	0.642791412060456
GO:0016874	ligase activity	50/5268	167/18639	0.29940119760479	1.05932781362105	0.341902348730158	0.657889300235352
GO:0004549	tRNA-specific ribonuclease activity	6/5268	17/18639	0.352941176470588	1.24876055205681	0.341926084560146	0.657889300235352
GO:0004550	nucleoside diphosphate kinase activity	6/5268	17/18639	0.352941176470588	1.24876055205681	0.341926084560146	0.657889300235352
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	6/5268	17/18639	0.352941176470588	1.24876055205681	0.341926084560146	0.657889300235352
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	6/5268	17/18639	0.352941176470588	1.24876055205681	0.341926084560146	0.657889300235352
GO:0019198	transmembrane receptor protein phosphatase activity	6/5268	17/18639	0.352941176470588	1.24876055205681	0.341926084560146	0.657889300235352
GO:1901567	fatty acid derivative binding	6/5268	17/18639	0.352941176470588	1.24876055205681	0.341926084560146	0.657889300235352
GO:0023023	MHC protein complex binding	12/5268	37/18639	0.324324324324324	1.14750969648464	0.34346689848153	0.659908504521738
GO:0016836	hydro-lyase activity	19/5268	61/18639	0.311475409836066	1.10204824676052	0.353384228130456	0.67799288339886
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	11/5268	34/18639	0.323529411764706	1.14469717271875	0.358192941381041	0.683604666984255
GO:0008191	metalloendopeptidase inhibitor activity	5/5268	14/18639	0.357142857142857	1.26362674910511	0.359363287334985	0.683604666984255
GO:0008195	phosphatidate phosphatase activity	5/5268	14/18639	0.357142857142857	1.26362674910511	0.359363287334985	0.683604666984255
GO:0016530	metallochaperone activity	5/5268	14/18639	0.357142857142857	1.26362674910511	0.359363287334985	0.683604666984255
GO:0019992	diacylglycerol binding	5/5268	14/18639	0.357142857142857	1.26362674910511	0.359363287334985	0.683604666984255
GO:1901612	cardiolipin binding	5/5268	14/18639	0.357142857142857	1.26362674910511	0.359363287334985	0.683604666984255
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	8/5268	24/18639	0.333333333333333	1.17938496583144	0.361724558989332	0.685184883952993
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	8/5268	24/18639	0.333333333333333	1.17938496583144	0.361724558989332	0.685184883952993
GO:0050699	WW domain binding	8/5268	24/18639	0.333333333333333	1.17938496583144	0.361724558989332	0.685184883952993
GO:0016877	ligase activity, forming carbon-sulfur bonds	13/5268	41/18639	0.317073170731707	1.12185399188844	0.36738275080903	0.694922583572573
GO:0016878	acid-thiol ligase activity	10/5268	31/18639	0.32258064516129	1.14134028951429	0.374245546012175	0.705664722895531
GO:0005114	type II transforming growth factor beta receptor binding	4/5268	11/18639	0.363636363636364	1.28660178090702	0.379574480601106	0.705664722895531
GO:0005225	volume-sensitive anion channel activity	4/5268	11/18639	0.363636363636364	1.28660178090702	0.379574480601106	0.705664722895531
GO:0005536	D-glucose binding	4/5268	11/18639	0.363636363636364	1.28660178090702	0.379574480601106	0.705664722895531
GO:0008172	S-methyltransferase activity	4/5268	11/18639	0.363636363636364	1.28660178090702	0.379574480601106	0.705664722895531
GO:0008526	phosphatidylinositol transfer activity	4/5268	11/18639	0.363636363636364	1.28660178090702	0.379574480601106	0.705664722895531
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	4/5268	11/18639	0.363636363636364	1.28660178090702	0.379574480601106	0.705664722895531
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	4/5268	11/18639	0.363636363636364	1.28660178090702	0.379574480601106	0.705664722895531
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	4/5268	11/18639	0.363636363636364	1.28660178090702	0.379574480601106	0.705664722895531
GO:0048185	activin binding	4/5268	11/18639	0.363636363636364	1.28660178090702	0.379574480601106	0.705664722895531
GO:0070697	activin receptor binding	4/5268	11/18639	0.363636363636364	1.28660178090702	0.379574480601106	0.705664722895531
GO:1900750	oligopeptide binding	4/5268	11/18639	0.363636363636364	1.28660178090702	0.379574480601106	0.705664722895531
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	7/5268	21/18639	0.333333333333333	1.17938496583144	0.379892475542419	0.705664722895531
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	26/5268	86/18639	0.302325581395349	1.06967473645177	0.381290245729995	0.707282872949424
GO:0000146	microfilament motor activity	12/5268	38/18639	0.315789473684211	1.11731207289294	0.382939576841484	0.709362554066363
GO:0046625	sphingolipid binding	9/5268	28/18639	0.321428571428571	1.1372640741946	0.391889246790114	0.724941127326616
GO:0001786	phosphatidylserine binding	18/5268	59/18639	0.305084745762712	1.07943708737114	0.398108794712336	0.734423229805861
GO:0070888	E-box binding	18/5268	59/18639	0.305084745762712	1.07943708737114	0.398108794712336	0.734423229805861
GO:0008308	voltage-gated monoatomic anion channel activity	6/5268	18/18639	0.333333333333333	1.17938496583144	0.400535762289973	0.734862744201412
GO:0017128	phospholipid scramblase activity	6/5268	18/18639	0.333333333333333	1.17938496583144	0.400535762289973	0.734862744201412
GO:1901611	phosphatidylglycerol binding	6/5268	18/18639	0.333333333333333	1.17938496583144	0.400535762289973	0.734862744201412
GO:1990381	ubiquitin-specific protease binding	6/5268	18/18639	0.333333333333333	1.17938496583144	0.400535762289973	0.734862744201412
GO:0022853	active monoatomic ion transmembrane transporter activity	35/5268	118/18639	0.296610169491525	1.04945272383306	0.401511314049923	0.735647605414797
GO:0004520	DNA endonuclease activity	13/5268	42/18639	0.30952380952381	1.09514318255776	0.40543637170502	0.741827039781801
GO:0019706	protein-cysteine S-palmitoyltransferase activity	8/5268	25/18639	0.32	1.13220956719818	0.411482023958639	0.750842877957135
GO:0019707	protein-cysteine S-acyltransferase activity	8/5268	25/18639	0.32	1.13220956719818	0.411482023958639	0.750842877957135
GO:0019212	phosphatase inhibitor activity	17/5268	56/18639	0.303571428571429	1.07408273673934	0.412828036462289	0.752276869699938
GO:0071813	lipoprotein particle binding	10/5268	32/18639	0.3125	1.10567340546697	0.418237813328627	0.759045112568036
GO:0071814	protein-lipid complex binding	10/5268	32/18639	0.3125	1.10567340546697	0.418237813328627	0.759045112568036
GO:0120015	sterol transfer activity	10/5268	32/18639	0.3125	1.10567340546697	0.418237813328627	0.759045112568036
GO:0005041	low-density lipoprotein particle receptor activity	5/5268	15/18639	0.333333333333333	1.17938496583144	0.42454462099734	0.767380115746202
GO:0008252	nucleotidase activity	5/5268	15/18639	0.333333333333333	1.17938496583144	0.42454462099734	0.767380115746202
GO:0050700	CARD domain binding	5/5268	15/18639	0.333333333333333	1.17938496583144	0.42454462099734	0.767380115746202
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	14/5268	46/18639	0.304347826086957	1.07682975141131	0.426043432750264	0.769054207236027
GO:0004864	protein phosphatase inhibitor activity	16/5268	53/18639	0.30188679245283	1.06812223320583	0.428440457212901	0.772342998707284
GO:0016881	acid-amino acid ligase activity	7/5268	22/18639	0.318181818181818	1.12577655829364	0.433525703544854	0.779474777123499
GO:0030971	receptor tyrosine kinase binding	24/5268	81/18639	0.296296296296296	1.04834219185016	0.433557452353874	0.779474777123499
GO:0016417	S-acyltransferase activity	9/5268	29/18639	0.310344827586207	1.09804807163616	0.438517673070857	0.787338549377221
GO:0045505	dynein intermediate chain binding	11/5268	36/18639	0.305555555555556	1.08110288534548	0.441616803288755	0.791844281464349
GO:0008013	beta-catenin binding	31/5268	106/18639	0.292452830188679	1.03474341341815	0.447392828963797	0.800222934311819
GO:0003720	telomerase activity	4/5268	12/18639	0.333333333333333	1.17938496583144	0.453439801199772	0.800222934311819
GO:0005165	neurotrophin receptor binding	4/5268	12/18639	0.333333333333333	1.17938496583144	0.453439801199772	0.800222934311819
GO:0016208	AMP binding	4/5268	12/18639	0.333333333333333	1.17938496583144	0.453439801199772	0.800222934311819
GO:0016840	carbon-nitrogen lyase activity	4/5268	12/18639	0.333333333333333	1.17938496583144	0.453439801199772	0.800222934311819
GO:0035014	phosphatidylinositol 3-kinase regulator activity	4/5268	12/18639	0.333333333333333	1.17938496583144	0.453439801199772	0.800222934311819
GO:0045295	gamma-catenin binding	4/5268	12/18639	0.333333333333333	1.17938496583144	0.453439801199772	0.800222934311819
GO:0097677	STAT family protein binding	4/5268	12/18639	0.333333333333333	1.17938496583144	0.453439801199772	0.800222934311819
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	4/5268	12/18639	0.333333333333333	1.17938496583144	0.453439801199772	0.800222934311819
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	4/5268	12/18639	0.333333333333333	1.17938496583144	0.453439801199772	0.800222934311819
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	4/5268	12/18639	0.333333333333333	1.17938496583144	0.453439801199772	0.800222934311819
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	4/5268	12/18639	0.333333333333333	1.17938496583144	0.453439801199772	0.800222934311819
GO:0008194	UDP-glycosyltransferase activity	42/5268	145/18639	0.289655172413793	1.02484486686042	0.45659790398992	0.801893438880517
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	6/5268	19/18639	0.315789473684211	1.11731207289294	0.458755391601254	0.801893438880517
GO:0015245	fatty acid transmembrane transporter activity	6/5268	19/18639	0.315789473684211	1.11731207289294	0.458755391601254	0.801893438880517
GO:0031420	alkali metal ion binding	6/5268	19/18639	0.315789473684211	1.11731207289294	0.458755391601254	0.801893438880517
GO:0042577	lipid phosphatase activity	6/5268	19/18639	0.315789473684211	1.11731207289294	0.458755391601254	0.801893438880517
GO:0046624	sphingolipid transporter activity	6/5268	19/18639	0.315789473684211	1.11731207289294	0.458755391601254	0.801893438880517
GO:0097001	ceramide binding	6/5268	19/18639	0.315789473684211	1.11731207289294	0.458755391601254	0.801893438880517
GO:0004112	cyclic-nucleotide phosphodiesterase activity	8/5268	26/18639	0.307692307692308	1.08866304538286	0.461060983881287	0.801893438880517
GO:0008157	protein phosphatase 1 binding	8/5268	26/18639	0.307692307692308	1.08866304538286	0.461060983881287	0.801893438880517
GO:0008198	ferrous iron binding	8/5268	26/18639	0.307692307692308	1.08866304538286	0.461060983881287	0.801893438880517
GO:0003777	microtubule motor activity	20/5268	68/18639	0.294117647058824	1.04063379338068	0.462105447626223	0.801893438880517
GO:0140223	general transcription initiation factor activity	20/5268	68/18639	0.294117647058824	1.04063379338068	0.462105447626223	0.801893438880517
GO:0019956	chemokine binding	10/5268	33/18639	0.303030303030303	1.07216815075585	0.462148564179836	0.801893438880517
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	138/5268	484/18639	0.285123966942149	1.00881276002937	0.468457659642469	0.811791789548175
GO:0031210	phosphatidylcholine binding	9/5268	30/18639	0.3	1.06144646924829	0.484712876517423	0.838610422525486
GO:0031681	G-protein beta-subunit binding	7/5268	23/18639	0.304347826086957	1.07682975141131	0.486431510906443	0.838610422525486
GO:0043274	phospholipase binding	7/5268	23/18639	0.304347826086957	1.07682975141131	0.486431510906443	0.838610422525486
GO:0140103	catalytic activity, acting on a glycoprotein	7/5268	23/18639	0.304347826086957	1.07682975141131	0.486431510906443	0.838610422525486
GO:0004708	MAP kinase kinase activity	5/5268	16/18639	0.3125	1.10567340546697	0.48831042165505	0.838620071972803
GO:0005024	transforming growth factor beta receptor activity	5/5268	16/18639	0.3125	1.10567340546697	0.48831042165505	0.838620071972803
GO:0005324	long-chain fatty acid transmembrane transporter activity	5/5268	16/18639	0.3125	1.10567340546697	0.48831042165505	0.838620071972803
GO:0098631	cell adhesion mediator activity	22/5268	76/18639	0.289473684210526	1.02420273348519	0.490607654018565	0.841489245653809
GO:0008376	acetylgalactosaminyltransferase activity	10/5268	34/18639	0.294117647058824	1.04063379338068	0.505463407012668	0.863660757783732
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	10/5268	34/18639	0.294117647058824	1.04063379338068	0.505463407012668	0.863660757783732
GO:0016831	carboxy-lyase activity	10/5268	34/18639	0.294117647058824	1.04063379338068	0.505463407012668	0.863660757783732
GO:0001216	DNA-binding transcription activator activity	139/5268	491/18639	0.283095723014257	1.00163651884258	0.50827272341395	0.866546156067985
GO:0008235	metalloexopeptidase activity	19/5268	66/18639	0.287878787878788	1.01855974321806	0.508860443805862	0.866546156067985
GO:0005044	scavenger receptor activity	8/5268	27/18639	0.296296296296296	1.04834219185016	0.509733032981168	0.866546156067985
GO:0016405	CoA-ligase activity	8/5268	27/18639	0.296296296296296	1.04834219185016	0.509733032981168	0.866546156067985
GO:0036002	pre-mRNA binding	17/5268	59/18639	0.288135593220339	1.01946836029497	0.511843974645493	0.869034712956886
GO:0033218	amide binding	70/5268	247/18639	0.283400809716599	1.00271596285264	0.513600839472807	0.870735157052075
GO:0016004	phospholipase activator activity	6/5268	20/18639	0.3	1.06144646924829	0.515438905328667	0.870735157052075
GO:0016408	C-acyltransferase activity	6/5268	20/18639	0.3	1.06144646924829	0.515438905328667	0.870735157052075
GO:0140939	histone H4 methyltransferase activity	6/5268	20/18639	0.3	1.06144646924829	0.515438905328667	0.870735157052075
GO:0003964	RNA-directed DNA polymerase activity	4/5268	13/18639	0.307692307692308	1.08866304538286	0.524094390713916	0.879823458410987
GO:0005035	death receptor activity	4/5268	13/18639	0.307692307692308	1.08866304538286	0.524094390713916	0.879823458410987
GO:0030955	potassium ion binding	4/5268	13/18639	0.307692307692308	1.08866304538286	0.524094390713916	0.879823458410987
GO:0061459	L-arginine transmembrane transporter activity	4/5268	13/18639	0.307692307692308	1.08866304538286	0.524094390713916	0.879823458410987
GO:0070123	transforming growth factor beta receptor activity, type III	4/5268	13/18639	0.307692307692308	1.08866304538286	0.524094390713916	0.879823458410987
GO:0005507	copper ion binding	18/5268	63/18639	0.285714285714286	1.01090139928409	0.526064654940749	0.882028503851967
GO:0005315	phosphate transmembrane transporter activity	7/5268	24/18639	0.291666666666667	1.03196184510251	0.537781432284077	0.897193122431697
GO:0030552	cAMP binding	7/5268	24/18639	0.291666666666667	1.03196184510251	0.537781432284077	0.897193122431697
GO:0060229	lipase activator activity	7/5268	24/18639	0.291666666666667	1.03196184510251	0.537781432284077	0.897193122431697
GO:0140612	DNA damage sensor activity	7/5268	24/18639	0.291666666666667	1.03196184510251	0.537781432284077	0.897193122431697
GO:0043178	alcohol binding	26/5268	92/18639	0.282608695652174	0.999913340596217	0.539793512607545	0.899432614679818
GO:0042277	peptide binding	70/5268	249/18639	0.281124497991968	0.994662019375909	0.545444104873611	0.907721725954473
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	5/5268	17/18639	0.294117647058824	1.04063379338068	0.549303895444593	0.912229256738195
GO:0005544	calcium-dependent phospholipid binding	15/5268	53/18639	0.283018867924528	1.00136459363046	0.549511145719434	0.912229256738195
GO:0045499	chemorepellent activity	8/5268	28/18639	0.285714285714286	1.01090139928409	0.556870547457589	0.920637776098161
GO:0016247	channel regulator activity	47/5268	168/18639	0.279761904761905	0.989840953465669	0.562394208237906	0.920637776098161
GO:0000217	DNA secondary structure binding	11/5268	39/18639	0.282051282051282	0.997941124934291	0.563709777282488	0.920637776098161
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	11/5268	39/18639	0.282051282051282	0.997941124934291	0.563709777282488	0.920637776098161
GO:0003680	minor groove of adenine-thymine-rich DNA binding	3/5268	10/18639	0.3	1.06144646924829	0.569641052938076	0.920637776098161
GO:0005031	tumor necrosis factor receptor activity	3/5268	10/18639	0.3	1.06144646924829	0.569641052938076	0.920637776098161
GO:0005131	growth hormone receptor binding	3/5268	10/18639	0.3	1.06144646924829	0.569641052938076	0.920637776098161
GO:0008140	cAMP response element binding protein binding	3/5268	10/18639	0.3	1.06144646924829	0.569641052938076	0.920637776098161
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	3/5268	10/18639	0.3	1.06144646924829	0.569641052938076	0.920637776098161
GO:0008641	ubiquitin-like modifier activating enzyme activity	3/5268	10/18639	0.3	1.06144646924829	0.569641052938076	0.920637776098161
GO:0015279	store-operated calcium channel activity	3/5268	10/18639	0.3	1.06144646924829	0.569641052938076	0.920637776098161
GO:0015658	branched-chain amino acid transmembrane transporter activity	3/5268	10/18639	0.3	1.06144646924829	0.569641052938076	0.920637776098161
GO:0032356	oxidized DNA binding	3/5268	10/18639	0.3	1.06144646924829	0.569641052938076	0.920637776098161
GO:0033204	ribonuclease P RNA binding	3/5268	10/18639	0.3	1.06144646924829	0.569641052938076	0.920637776098161
GO:0035374	chondroitin sulfate binding	3/5268	10/18639	0.3	1.06144646924829	0.569641052938076	0.920637776098161
GO:0042975	peroxisome proliferator activated receptor binding	3/5268	10/18639	0.3	1.06144646924829	0.569641052938076	0.920637776098161
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	3/5268	10/18639	0.3	1.06144646924829	0.569641052938076	0.920637776098161
GO:0097177	mitochondrial ribosome binding	3/5268	10/18639	0.3	1.06144646924829	0.569641052938076	0.920637776098161
GO:0140135	mechanosensitive monoatomic cation channel activity	3/5268	10/18639	0.3	1.06144646924829	0.569641052938076	0.920637776098161
GO:1990757	ubiquitin ligase activator activity	3/5268	10/18639	0.3	1.06144646924829	0.569641052938076	0.920637776098161
GO:0010314	phosphatidylinositol-5-phosphate binding	6/5268	21/18639	0.285714285714286	1.01090139928409	0.569657477243166	0.920637776098161
GO:0015174	basic amino acid transmembrane transporter activity	6/5268	21/18639	0.285714285714286	1.01090139928409	0.569657477243166	0.920637776098161
GO:0003707	nuclear steroid receptor activity	7/5268	25/18639	0.28	0.990683371298405	0.586897868855081	0.942154952989241
GO:0008483	transaminase activity	7/5268	25/18639	0.28	0.990683371298405	0.586897868855081	0.942154952989241
GO:0015645	fatty acid ligase activity	7/5268	25/18639	0.28	0.990683371298405	0.586897868855081	0.942154952989241
GO:0120515	fatty acid-CoA ligase activity	7/5268	25/18639	0.28	0.990683371298405	0.586897868855081	0.942154952989241
GO:0008474	palmitoyl-(protein) hydrolase activity	4/5268	14/18639	0.285714285714286	1.01090139928409	0.589986832065489	0.942154952989241
GO:0031404	chloride ion binding	4/5268	14/18639	0.285714285714286	1.01090139928409	0.589986832065489	0.942154952989241
GO:0034236	protein kinase A catalytic subunit binding	4/5268	14/18639	0.285714285714286	1.01090139928409	0.589986832065489	0.942154952989241
GO:0042043	neurexin family protein binding	4/5268	14/18639	0.285714285714286	1.01090139928409	0.589986832065489	0.942154952989241
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	4/5268	14/18639	0.285714285714286	1.01090139928409	0.589986832065489	0.942154952989241
GO:0098599	palmitoyl hydrolase activity	4/5268	14/18639	0.285714285714286	1.01090139928409	0.589986832065489	0.942154952989241
GO:0015399	primary active transmembrane transporter activity	46/5268	166/18639	0.27710843373494	0.980452561956253	0.592349016520302	0.944803716373831
GO:0141108	transporter regulator activity	47/5268	170/18639	0.276470588235294	0.978195765777837	0.599984627231239	0.955847395458546
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	11/5268	40/18639	0.275	0.972992596810934	0.602052996686517	0.956872395917151
GO:0050997	quaternary ammonium group binding	11/5268	40/18639	0.275	0.972992596810934	0.602052996686517	0.956872395917151
GO:0005010	insulin-like growth factor receptor activity	14/5268	51/18639	0.274509803921569	0.9712582071553	0.603829570589588	0.958305404950266
GO:0000400	four-way junction DNA binding	5/5268	18/18639	0.277777777777778	0.982820804859529	0.606522408196371	0.958305404950266
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	5/5268	18/18639	0.277777777777778	0.982820804859529	0.606522408196371	0.958305404950266
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	5/5268	18/18639	0.277777777777778	0.982820804859529	0.606522408196371	0.958305404950266
GO:0030228	lipoprotein particle receptor activity	5/5268	18/18639	0.277777777777778	0.982820804859529	0.606522408196371	0.958305404950266
GO:0099106	ion channel regulator activity	44/5268	160/18639	0.275	0.972992596810934	0.614815728890024	0.969838048981968
GO:0098632	cell-cell adhesion mediator activity	15/5268	55/18639	0.272727272727273	0.964951335680265	0.615265835988561	0.969838048981968
GO:0043548	phosphatidylinositol 3-kinase binding	7/5268	26/18639	0.269230769230769	0.952580164710005	0.633258826477006	0.991647709203965
GO:0051139	metal cation:proton antiporter activity	7/5268	26/18639	0.269230769230769	0.952580164710005	0.633258826477006	0.991647709203965
GO:0097602	cullin family protein binding	7/5268	26/18639	0.269230769230769	0.952580164710005	0.633258826477006	0.991647709203965
GO:0042169	SH2 domain binding	11/5268	41/18639	0.268292682926829	0.949261070059448	0.638727028142584	0.991647709203965
GO:0140828	metal cation:monoatomic cation antiporter activity	11/5268	41/18639	0.268292682926829	0.949261070059448	0.638727028142584	0.991647709203965
GO:0004016	adenylate cyclase activity	3/5268	11/18639	0.272727272727273	0.964951335680265	0.640916017564439	0.991647709203965
GO:0015173	aromatic amino acid transmembrane transporter activity	3/5268	11/18639	0.272727272727273	0.964951335680265	0.640916017564439	0.991647709203965
GO:0015217	ADP transmembrane transporter activity	3/5268	11/18639	0.272727272727273	0.964951335680265	0.640916017564439	0.991647709203965
GO:0032050	clathrin heavy chain binding	3/5268	11/18639	0.272727272727273	0.964951335680265	0.640916017564439	0.991647709203965
GO:0032794	GTPase activating protein binding	3/5268	11/18639	0.272727272727273	0.964951335680265	0.640916017564439	0.991647709203965
GO:0034056	estrogen response element binding	3/5268	11/18639	0.272727272727273	0.964951335680265	0.640916017564439	0.991647709203965
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	3/5268	11/18639	0.272727272727273	0.964951335680265	0.640916017564439	0.991647709203965
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	3/5268	11/18639	0.272727272727273	0.964951335680265	0.640916017564439	0.991647709203965
GO:0045294	alpha-catenin binding	3/5268	11/18639	0.272727272727273	0.964951335680265	0.640916017564439	0.991647709203965
GO:0050786	RAGE receptor binding	3/5268	11/18639	0.272727272727273	0.964951335680265	0.640916017564439	0.991647709203965
GO:0050998	nitric-oxide synthase binding	3/5268	11/18639	0.272727272727273	0.964951335680265	0.640916017564439	0.991647709203965
GO:0019199	transmembrane receptor protein kinase activity	21/5268	78/18639	0.269230769230769	0.952580164710005	0.645602595556885	0.996744606471727
GO:0046915	transition metal ion transmembrane transporter activity	12/5268	45/18639	0.266666666666667	0.943507972665148	0.64904930371769	0.996744606471727
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	4/5268	15/18639	0.266666666666667	0.943507972665148	0.65014763609027	0.996744606471727
GO:0016846	carbon-sulfur lyase activity	4/5268	15/18639	0.266666666666667	0.943507972665148	0.65014763609027	0.996744606471727
GO:0017081	chloride channel regulator activity	4/5268	15/18639	0.266666666666667	0.943507972665148	0.65014763609027	0.996744606471727
GO:0047372	monoacylglycerol lipase activity	4/5268	15/18639	0.266666666666667	0.943507972665148	0.65014763609027	0.996744606471727
GO:0050780	dopamine receptor binding	4/5268	15/18639	0.266666666666667	0.943507972665148	0.65014763609027	0.996744606471727
GO:0055105	ubiquitin-protein transferase inhibitor activity	4/5268	15/18639	0.266666666666667	0.943507972665148	0.65014763609027	0.996744606471727
GO:0140299	molecular sensor activity	19/5268	71/18639	0.267605633802817	0.946830183836504	0.654456445531384	1
GO:0004714	transmembrane receptor protein tyrosine kinase activity	16/5268	60/18639	0.266666666666667	0.943507972665148	0.655727369663734	1
GO:0008574	plus-end-directed microtubule motor activity	5/5268	19/18639	0.263157894736842	0.931093394077449	0.659296342694626	1
GO:0005496	steroid binding	29/5268	108/18639	0.268518518518519	0.950060111364212	0.663119599063172	1
GO:0008171	O-methyltransferase activity	6/5268	23/18639	0.260869565217391	0.922996929781123	0.668098203488358	1
GO:0016849	phosphorus-oxygen lyase activity	6/5268	23/18639	0.260869565217391	0.922996929781123	0.668098203488358	1
GO:0031492	nucleosomal DNA binding	11/5268	42/18639	0.261904761904762	0.926659616010413	0.673520915795907	1
GO:0004364	glutathione transferase activity	7/5268	27/18639	0.259259259259259	0.917299417868894	0.676492854200548	1
GO:0004683	calcium/calmodulin-dependent protein kinase activity	7/5268	27/18639	0.259259259259259	0.917299417868894	0.676492854200548	1
GO:0005385	zinc ion transmembrane transporter activity	7/5268	27/18639	0.259259259259259	0.917299417868894	0.676492854200548	1
GO:0005164	tumor necrosis factor receptor binding	8/5268	31/18639	0.258064516129032	0.913072231611434	0.684483071809613	1
GO:0008327	methyl-CpG binding	8/5268	31/18639	0.258064516129032	0.913072231611434	0.684483071809613	1
GO:0005006	epidermal growth factor receptor activity	13/5268	50/18639	0.26	0.919920273348519	0.689844074348453	1
GO:0032813	tumor necrosis factor receptor superfamily binding	13/5268	50/18639	0.26	0.919920273348519	0.689844074348453	1
GO:0008238	exopeptidase activity	27/5268	102/18639	0.264705882352941	0.93657041404261	0.691941386005153	1
GO:0072341	modified amino acid binding	24/5268	91/18639	0.263736263736264	0.933139753185311	0.693304345158844	1
GO:0004526	ribonuclease P activity	3/5268	12/18639	0.25	0.884538724373576	0.703408089685995	1
GO:0004859	phospholipase inhibitor activity	3/5268	12/18639	0.25	0.884538724373576	0.703408089685995	1
GO:0005025	transforming growth factor beta receptor activity, type I	3/5268	12/18639	0.25	0.884538724373576	0.703408089685995	1
GO:0005026	transforming growth factor beta receptor activity, type II	3/5268	12/18639	0.25	0.884538724373576	0.703408089685995	1
GO:0005247	voltage-gated chloride channel activity	3/5268	12/18639	0.25	0.884538724373576	0.703408089685995	1
GO:0015368	calcium:monoatomic cation antiporter activity	3/5268	12/18639	0.25	0.884538724373576	0.703408089685995	1
GO:0016361	activin receptor activity, type I	3/5268	12/18639	0.25	0.884538724373576	0.703408089685995	1
GO:0016362	activin receptor activity, type II	3/5268	12/18639	0.25	0.884538724373576	0.703408089685995	1
GO:0016423	tRNA (guanine) methyltransferase activity	3/5268	12/18639	0.25	0.884538724373576	0.703408089685995	1
GO:0016801	hydrolase activity, acting on ether bonds	3/5268	12/18639	0.25	0.884538724373576	0.703408089685995	1
GO:0016803	ether hydrolase activity	3/5268	12/18639	0.25	0.884538724373576	0.703408089685995	1
GO:0017002	activin receptor activity	3/5268	12/18639	0.25	0.884538724373576	0.703408089685995	1
GO:0042301	phosphate ion binding	3/5268	12/18639	0.25	0.884538724373576	0.703408089685995	1
GO:0070008	serine-type exopeptidase activity	3/5268	12/18639	0.25	0.884538724373576	0.703408089685995	1
GO:0097371	MDM2/MDM4 family protein binding	3/5268	12/18639	0.25	0.884538724373576	0.703408089685995	1
GO:1990459	transferrin receptor binding	3/5268	12/18639	0.25	0.884538724373576	0.703408089685995	1
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	4/5268	16/18639	0.25	0.884538724373576	0.704093374235344	1
GO:0015385	sodium:proton antiporter activity	4/5268	16/18639	0.25	0.884538724373576	0.704093374235344	1
GO:0015562	efflux transmembrane transporter activity	4/5268	16/18639	0.25	0.884538724373576	0.704093374235344	1
GO:0031435	mitogen-activated protein kinase kinase kinase binding	4/5268	16/18639	0.25	0.884538724373576	0.704093374235344	1
GO:0055102	lipase inhibitor activity	4/5268	16/18639	0.25	0.884538724373576	0.704093374235344	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	11/5268	43/18639	0.255813953488372	0.905109392382264	0.706278752030252	1
GO:0001972	retinoic acid binding	5/5268	20/18639	0.25	0.884538724373576	0.707248821816612	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	6/5268	24/18639	0.25	0.884538724373576	0.711537127223119	1
GO:0016866	intramolecular transferase activity	7/5268	28/18639	0.25	0.884538724373576	0.716366956448201	1
GO:0005021	vascular endothelial growth factor receptor activity	13/5268	51/18639	0.254901960784314	0.901882620929921	0.719270088792275	1
GO:0005030	neurotrophin receptor activity	13/5268	51/18639	0.254901960784314	0.901882620929921	0.719270088792275	1
GO:0016830	carbon-carbon lyase activity	13/5268	51/18639	0.254901960784314	0.901882620929921	0.719270088792275	1
GO:0043425	bHLH transcription factor binding	8/5268	32/18639	0.25	0.884538724373576	0.721444247778622	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	48/5268	181/18639	0.265193370165746	0.938295221434954	0.725376359706851	1
GO:0005200	structural constituent of cytoskeleton	29/5268	112/18639	0.258928571428571	0.916129393101204	0.7438574971929	1
GO:0005123	death receptor binding	5/5268	21/18639	0.238095238095238	0.842417832736739	0.750246116995815	1
GO:0005248	voltage-gated sodium channel activity	5/5268	21/18639	0.238095238095238	0.842417832736739	0.750246116995815	1
GO:0009975	cyclase activity	5/5268	21/18639	0.238095238095238	0.842417832736739	0.750246116995815	1
GO:0061891	calcium ion sensor activity	5/5268	21/18639	0.238095238095238	0.842417832736739	0.750246116995815	1
GO:0005537	D-mannose binding	6/5268	25/18639	0.24	0.849157175398633	0.750896893023552	1
GO:0004029	aldehyde dehydrogenase (NAD+) activity	4/5268	17/18639	0.235294117647059	0.832507034704542	0.751720906170959	1
GO:0015278	intracellularly gated calcium channel activity	4/5268	17/18639	0.235294117647059	0.832507034704542	0.751720906170959	1
GO:0036041	long-chain fatty acid binding	4/5268	17/18639	0.235294117647059	0.832507034704542	0.751720906170959	1
GO:0070402	NADPH binding	4/5268	17/18639	0.235294117647059	0.832507034704542	0.751720906170959	1
GO:0004629	phospholipase C activity	7/5268	29/18639	0.241379310344828	0.85403738905035	0.752770010898337	1
GO:0099604	ligand-gated calcium channel activity	7/5268	29/18639	0.241379310344828	0.85403738905035	0.752770010898337	1
GO:0019239	deaminase activity	8/5268	33/18639	0.242424242424242	0.85773452060468	0.755380435452223	1
GO:0002161	aminoacyl-tRNA editing activity	3/5268	13/18639	0.230769230769231	0.816497284037147	0.757202199377619	1
GO:0017154	semaphorin receptor activity	3/5268	13/18639	0.230769230769231	0.816497284037147	0.757202199377619	1
GO:0035673	oligopeptide transmembrane transporter activity	3/5268	13/18639	0.230769230769231	0.816497284037147	0.757202199377619	1
GO:0039706	co-receptor binding	3/5268	13/18639	0.230769230769231	0.816497284037147	0.757202199377619	1
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	3/5268	13/18639	0.230769230769231	0.816497284037147	0.757202199377619	1
GO:0140410	monoatomic cation:bicarbonate symporter activity	3/5268	13/18639	0.230769230769231	0.816497284037147	0.757202199377619	1
GO:0030551	cyclic nucleotide binding	9/5268	37/18639	0.243243243243243	0.86063227236348	0.758446705979866	1
GO:0070851	growth factor receptor binding	36/5268	139/18639	0.258992805755396	0.916356664099245	0.760846915539958	1
GO:0005004	GPI-linked ephrin receptor activity	12/5268	49/18639	0.244897959183673	0.866486913672075	0.768938469077738	1
GO:0005008	hepatocyte growth factor receptor activity	12/5268	49/18639	0.244897959183673	0.866486913672075	0.768938469077738	1
GO:0005009	insulin receptor activity	12/5268	49/18639	0.244897959183673	0.866486913672075	0.768938469077738	1
GO:0005011	macrophage colony-stimulating factor receptor activity	12/5268	49/18639	0.244897959183673	0.866486913672075	0.768938469077738	1
GO:0005018	platelet-derived growth factor alpha-receptor activity	12/5268	49/18639	0.244897959183673	0.866486913672075	0.768938469077738	1
GO:0005020	stem cell factor receptor activity	12/5268	49/18639	0.244897959183673	0.866486913672075	0.768938469077738	1
GO:0008288	boss receptor activity	12/5268	49/18639	0.244897959183673	0.866486913672075	0.768938469077738	1
GO:0036332	placental growth factor receptor activity	12/5268	49/18639	0.244897959183673	0.866486913672075	0.768938469077738	1
GO:0038062	protein tyrosine kinase collagen receptor activity	12/5268	49/18639	0.244897959183673	0.866486913672075	0.768938469077738	1
GO:0060175	brain-derived neurotrophic factor receptor activity	12/5268	49/18639	0.244897959183673	0.866486913672075	0.768938469077738	1
GO:0015078	proton transmembrane transporter activity	48/5268	185/18639	0.259459459459459	0.918007757187712	0.782591318711126	1
GO:0008106	alcohol dehydrogenase (NADP+) activity	7/5268	30/18639	0.233333333333333	0.825569476082005	0.785693840634083	1
GO:0033612	receptor serine/threonine kinase binding	7/5268	30/18639	0.233333333333333	0.825569476082005	0.785693840634083	1
GO:0098918	structural constituent of synapse	7/5268	30/18639	0.233333333333333	0.825569476082005	0.785693840634083	1
GO:0004435	phosphatidylinositol phospholipase C activity	6/5268	26/18639	0.230769230769231	0.816497284037147	0.786188312987516	1
GO:0051427	hormone receptor binding	8/5268	34/18639	0.235294117647059	0.832507034704542	0.786276399332428	1
GO:0090482	vitamin transmembrane transporter activity	8/5268	34/18639	0.235294117647059	0.832507034704542	0.786276399332428	1
GO:0042887	amide transmembrane transporter activity	9/5268	38/18639	0.236842105263158	0.837984054669704	0.787581259353644	1
GO:0031683	G-protein beta/gamma-subunit complex binding	5/5268	22/18639	0.227272727272727	0.804126113066887	0.788345888941633	1
GO:0140784	metal ion sensor activity	5/5268	22/18639	0.227272727272727	0.804126113066887	0.788345888941633	1
GO:0016854	racemase and epimerase activity	4/5268	18/18639	0.222222222222222	0.786256643887623	0.793206191306556	1
GO:0098641	cadherin binding involved in cell-cell adhesion	4/5268	18/18639	0.222222222222222	0.786256643887623	0.793206191306556	1
GO:0005007	fibroblast growth factor receptor activity	12/5268	50/18639	0.24	0.849157175398633	0.793915646360669	1
GO:0005017	platelet-derived growth factor receptor activity	12/5268	50/18639	0.24	0.849157175398633	0.793915646360669	1
GO:0005019	platelet-derived growth factor beta-receptor activity	12/5268	50/18639	0.24	0.849157175398633	0.793915646360669	1
GO:0016758	hexosyltransferase activity	51/5268	197/18639	0.258883248730964	0.915969034376698	0.793918658556688	1
GO:0008494	translation activator activity	3/5268	14/18639	0.214285714285714	0.758176049463065	0.802806390462745	1
GO:0008559	ABC-type xenobiotic transporter activity	3/5268	14/18639	0.214285714285714	0.758176049463065	0.802806390462745	1
GO:0015386	potassium:proton antiporter activity	3/5268	14/18639	0.214285714285714	0.758176049463065	0.802806390462745	1
GO:0015926	glucosidase activity	3/5268	14/18639	0.214285714285714	0.758176049463065	0.802806390462745	1
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	3/5268	14/18639	0.214285714285714	0.758176049463065	0.802806390462745	1
GO:0042813	Wnt receptor activity	3/5268	14/18639	0.214285714285714	0.758176049463065	0.802806390462745	1
GO:0098821	BMP receptor activity	3/5268	14/18639	0.214285714285714	0.758176049463065	0.802806390462745	1
GO:0016782	transferase activity, transferring sulphur-containing groups	17/5268	70/18639	0.242857142857143	0.859266189391474	0.807519698595368	1
GO:0017147	Wnt-protein binding	7/5268	31/18639	0.225806451612903	0.798938202660004	0.815213648207887	1
GO:0047499	calcium-independent phospholipase A2 activity	7/5268	31/18639	0.225806451612903	0.798938202660004	0.815213648207887	1
GO:0072349	modified amino acid transmembrane transporter activity	7/5268	31/18639	0.225806451612903	0.798938202660004	0.815213648207887	1
GO:0008237	metallopeptidase activity	47/5268	184/18639	0.255434782608696	0.90376782707735	0.816902092776349	1
GO:0016209	antioxidant activity	21/5268	86/18639	0.244186046511628	0.863968056364888	0.818821591382451	1
GO:0004602	glutathione peroxidase activity	5/5268	23/18639	0.217391304347826	0.769164108150936	0.821748023789764	1
GO:0099186	structural constituent of postsynapse	5/5268	23/18639	0.217391304347826	0.769164108150936	0.821748023789764	1
GO:0008519	ammonium channel activity	2/5268	10/18639	0.2	0.707630979498861	0.821783346144405	1
GO:0015643	toxic substance binding	2/5268	10/18639	0.2	0.707630979498861	0.821783346144405	1
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	2/5268	10/18639	0.2	0.707630979498861	0.821783346144405	1
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	2/5268	10/18639	0.2	0.707630979498861	0.821783346144405	1
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	2/5268	10/18639	0.2	0.707630979498861	0.821783346144405	1
GO:0019531	oxalate transmembrane transporter activity	2/5268	10/18639	0.2	0.707630979498861	0.821783346144405	1
GO:0050308	sugar-phosphatase activity	2/5268	10/18639	0.2	0.707630979498861	0.821783346144405	1
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	2/5268	10/18639	0.2	0.707630979498861	0.821783346144405	1
GO:0070097	delta-catenin binding	2/5268	10/18639	0.2	0.707630979498861	0.821783346144405	1
GO:0140940	histone H2A methyltransferase activity	2/5268	10/18639	0.2	0.707630979498861	0.821783346144405	1
GO:0141109	transporter activator activity	2/5268	10/18639	0.2	0.707630979498861	0.821783346144405	1
GO:1990259	histone H2AQ104 methyltransferase activity	2/5268	10/18639	0.2	0.707630979498861	0.821783346144405	1
GO:1990763	arrestin family protein binding	2/5268	10/18639	0.2	0.707630979498861	0.821783346144405	1
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	4/5268	19/18639	0.210526315789474	0.744874715261959	0.828915484269738	1
GO:0022821	solute:potassium antiporter activity	4/5268	19/18639	0.210526315789474	0.744874715261959	0.828915484269738	1
GO:0030506	ankyrin binding	4/5268	19/18639	0.210526315789474	0.744874715261959	0.828915484269738	1
GO:0043395	heparan sulfate proteoglycan binding	4/5268	19/18639	0.210526315789474	0.744874715261959	0.828915484269738	1
GO:0001540	amyloid-beta binding	20/5268	83/18639	0.240963855421687	0.852567445179351	0.833039744233451	1
GO:0004033	aldo-keto reductase (NADPH) activity	8/5268	36/18639	0.222222222222222	0.786256643887623	0.839203400532901	1
GO:0004190	aspartic-type endopeptidase activity	8/5268	36/18639	0.222222222222222	0.786256643887623	0.839203400532901	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	3/5268	15/18639	0.2	0.707630979498861	0.840971079055864	1
GO:0005402	carbohydrate:monoatomic cation symporter activity	3/5268	15/18639	0.2	0.707630979498861	0.840971079055864	1
GO:0015556	C4-dicarboxylate transmembrane transporter activity	3/5268	15/18639	0.2	0.707630979498861	0.840971079055864	1
GO:0015929	hexosaminidase activity	3/5268	15/18639	0.2	0.707630979498861	0.840971079055864	1
GO:0033130	acetylcholine receptor binding	3/5268	15/18639	0.2	0.707630979498861	0.840971079055864	1
GO:0048531	beta-1,3-galactosyltransferase activity	3/5268	15/18639	0.2	0.707630979498861	0.840971079055864	1
GO:0047498	calcium-dependent phospholipase A2 activity	7/5268	32/18639	0.21875	0.773971383826879	0.841469080328081	1
GO:0004622	lysophospholipase activity	5/5268	24/18639	0.208333333333333	0.737115603644647	0.850750891307303	1
GO:0005540	hyaluronic acid binding	5/5268	24/18639	0.208333333333333	0.737115603644647	0.850750891307303	1
GO:0030215	semaphorin receptor binding	5/5268	24/18639	0.208333333333333	0.737115603644647	0.850750891307303	1
GO:0005003	ephrin receptor activity	12/5268	53/18639	0.226415094339623	0.801091674904371	0.856992944651125	1
GO:0005005	transmembrane-ephrin receptor activity	12/5268	53/18639	0.226415094339623	0.801091674904371	0.856992944651125	1
GO:0017046	peptide hormone binding	12/5268	53/18639	0.226415094339623	0.801091674904371	0.856992944651125	1
GO:0038064	collagen receptor activity	12/5268	53/18639	0.226415094339623	0.801091674904371	0.856992944651125	1
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	4/5268	20/18639	0.2	0.707630979498861	0.859332149883019	1
GO:0140664	ATP-dependent DNA damage sensor activity	4/5268	20/18639	0.2	0.707630979498861	0.859332149883019	1
GO:0001530	lipopolysaccharide binding	9/5268	41/18639	0.219512195121951	0.776668148230457	0.859351409648821	1
GO:0004812	aminoacyl-tRNA ligase activity	9/5268	41/18639	0.219512195121951	0.776668148230457	0.859351409648821	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	9/5268	41/18639	0.219512195121951	0.776668148230457	0.859351409648821	1
GO:0042287	MHC protein binding	9/5268	41/18639	0.219512195121951	0.776668148230457	0.859351409648821	1
GO:0043394	proteoglycan binding	8/5268	37/18639	0.216216216216216	0.765006464323093	0.861481109375118	1
GO:0070001	aspartic-type peptidase activity	8/5268	37/18639	0.216216216216216	0.765006464323093	0.861481109375118	1
GO:0000099	sulfur amino acid transmembrane transporter activity	2/5268	11/18639	0.181818181818182	0.64330089045351	0.861976085828841	1
GO:0003953	NAD+ nucleosidase activity	2/5268	11/18639	0.181818181818182	0.64330089045351	0.861976085828841	1
GO:0004523	RNA-DNA hybrid ribonuclease activity	2/5268	11/18639	0.181818181818182	0.64330089045351	0.861976085828841	1
GO:0008271	secondary active sulfate transmembrane transporter activity	2/5268	11/18639	0.181818181818182	0.64330089045351	0.861976085828841	1
GO:0016176	superoxide-generating NADPH oxidase activator activity	2/5268	11/18639	0.181818181818182	0.64330089045351	0.861976085828841	1
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/5268	11/18639	0.181818181818182	0.64330089045351	0.861976085828841	1
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	2/5268	11/18639	0.181818181818182	0.64330089045351	0.861976085828841	1
GO:0019203	carbohydrate phosphatase activity	2/5268	11/18639	0.181818181818182	0.64330089045351	0.861976085828841	1
GO:0019215	intermediate filament binding	2/5268	11/18639	0.181818181818182	0.64330089045351	0.861976085828841	1
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	7/5268	33/18639	0.212121212121212	0.750517705529095	0.864646792410043	1
GO:0003785	actin monomer binding	6/5268	29/18639	0.206896551724138	0.732032047757442	0.869210997478008	1
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	3/5268	16/18639	0.1875	0.663404043280182	0.872558241706753	1
GO:0022858	alanine transmembrane transporter activity	3/5268	16/18639	0.1875	0.663404043280182	0.872558241706753	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	3/5268	16/18639	0.1875	0.663404043280182	0.872558241706753	1
GO:0015179	L-amino acid transmembrane transporter activity	14/5268	62/18639	0.225806451612903	0.798938202660004	0.873707913944751	1
GO:0000030	mannosyltransferase activity	5/5268	25/18639	0.2	0.707630979498861	0.875714390878241	1
GO:0015662	P-type ion transporter activity	5/5268	25/18639	0.2	0.707630979498861	0.875714390878241	1
GO:0047617	fatty acyl-CoA hydrolase activity	5/5268	25/18639	0.2	0.707630979498861	0.875714390878241	1
GO:0120020	cholesterol transfer activity	5/5268	25/18639	0.2	0.707630979498861	0.875714390878241	1
GO:0140358	P-type transmembrane transporter activity	5/5268	25/18639	0.2	0.707630979498861	0.875714390878241	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	7/5268	34/18639	0.205882352941176	0.728443655366474	0.884965042467202	1
GO:0001846	opsonin binding	4/5268	21/18639	0.19047619047619	0.673934266189391	0.884999451738832	1
GO:0036122	BMP binding	4/5268	21/18639	0.19047619047619	0.673934266189391	0.884999451738832	1
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	4/5268	21/18639	0.19047619047619	0.673934266189391	0.884999451738832	1
GO:0051428	peptide hormone receptor binding	4/5268	21/18639	0.19047619047619	0.673934266189391	0.884999451738832	1
GO:1904047	S-adenosyl-L-methionine binding	4/5268	21/18639	0.19047619047619	0.673934266189391	0.884999451738832	1
GO:0016597	amino acid binding	11/5268	51/18639	0.215686274509804	0.763131448479164	0.891149182735723	1
GO:0140359	ABC-type transporter activity	10/5268	47/18639	0.212765957446809	0.752798914360491	0.892937236029252	1
GO:0004032	aldose reductase (NADPH) activity	2/5268	12/18639	0.166666666666667	0.589692482915718	0.893689685057411	1
GO:0005436	sodium:phosphate symporter activity	2/5268	12/18639	0.166666666666667	0.589692482915718	0.893689685057411	1
GO:0008179	adenylate cyclase binding	2/5268	12/18639	0.166666666666667	0.589692482915718	0.893689685057411	1
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	2/5268	12/18639	0.166666666666667	0.589692482915718	0.893689685057411	1
GO:0015132	prostaglandin transmembrane transporter activity	2/5268	12/18639	0.166666666666667	0.589692482915718	0.893689685057411	1
GO:0015269	calcium-activated potassium channel activity	2/5268	12/18639	0.166666666666667	0.589692482915718	0.893689685057411	1
GO:0036009	protein-glutamine N-methyltransferase activity	2/5268	12/18639	0.166666666666667	0.589692482915718	0.893689685057411	1
GO:0070679	inositol 1,4,5 trisphosphate binding	2/5268	12/18639	0.166666666666667	0.589692482915718	0.893689685057411	1
GO:0140829	bicarbonate:monoatomic anion antiporter activity	2/5268	12/18639	0.166666666666667	0.589692482915718	0.893689685057411	1
GO:0140900	chloride:bicarbonate antiporter activity	2/5268	12/18639	0.166666666666667	0.589692482915718	0.893689685057411	1
GO:0005227	calcium-activated cation channel activity	5/5268	26/18639	0.192307692307692	0.680414403364289	0.897030123709365	1
GO:0016289	acyl-CoA hydrolase activity	5/5268	26/18639	0.192307692307692	0.680414403364289	0.897030123709365	1
GO:0008484	sulfuric ester hydrolase activity	3/5268	17/18639	0.176470588235294	0.624380276028407	0.898451956464423	1
GO:0008569	minus-end-directed microtubule motor activity	3/5268	17/18639	0.176470588235294	0.624380276028407	0.898451956464423	1
GO:0016805	dipeptidase activity	3/5268	17/18639	0.176470588235294	0.624380276028407	0.898451956464423	1
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	3/5268	17/18639	0.176470588235294	0.624380276028407	0.898451956464423	1
GO:0005518	collagen binding	16/5268	72/18639	0.222222222222222	0.786256643887623	0.900753001114305	1
GO:0052689	carboxylic ester hydrolase activity	21/5268	92/18639	0.228260869565217	0.807622313558483	0.901407018578439	1
GO:0004623	phospholipase A2 activity	7/5268	35/18639	0.2	0.707630979498861	0.902660571276533	1
GO:0016229	steroid dehydrogenase activity	7/5268	35/18639	0.2	0.707630979498861	0.902660571276533	1
GO:0170055	lipid transmembrane transporter activity	12/5268	56/18639	0.214285714285714	0.758176049463065	0.903820062875088	1
GO:0008970	phospholipase A1 activity	4/5268	22/18639	0.181818181818182	0.64330089045351	0.90647802124932	1
GO:0005452	solute:inorganic anion antiporter activity	6/5268	31/18639	0.193548387096774	0.684804173708575	0.908060679924453	1
GO:0016790	thiolester hydrolase activity	9/5268	44/18639	0.204545454545455	0.723713501760199	0.910237373789286	1
GO:0070279	vitamin B6 binding	12/5268	57/18639	0.210526315789474	0.744874715261959	0.916280272095231	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	7/5268	36/18639	0.194444444444444	0.687974563401671	0.917977819387065	1
GO:0016251	RNA polymerase II general transcription initiation factor activity	11/5268	53/18639	0.207547169811321	0.734334035329007	0.918127266544175	1
GO:0008417	fucosyltransferase activity	2/5268	13/18639	0.153846153846154	0.544331522691432	0.918505591544645	1
GO:0009982	pseudouridine synthase activity	2/5268	13/18639	0.153846153846154	0.544331522691432	0.918505591544645	1
GO:0031432	titin binding	2/5268	13/18639	0.153846153846154	0.544331522691432	0.918505591544645	1
GO:0070700	BMP receptor binding	2/5268	13/18639	0.153846153846154	0.544331522691432	0.918505591544645	1
GO:0071714	icosanoid transmembrane transporter activity	2/5268	13/18639	0.153846153846154	0.544331522691432	0.918505591544645	1
GO:0071837	HMG box domain binding	2/5268	13/18639	0.153846153846154	0.544331522691432	0.918505591544645	1
GO:0015172	acidic amino acid transmembrane transporter activity	3/5268	18/18639	0.166666666666667	0.589692482915718	0.919501109495996	1
GO:0015280	ligand-gated sodium channel activity	3/5268	18/18639	0.166666666666667	0.589692482915718	0.919501109495996	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	3/5268	18/18639	0.166666666666667	0.589692482915718	0.919501109495996	1
GO:0034185	apolipoprotein binding	3/5268	18/18639	0.166666666666667	0.589692482915718	0.919501109495996	1
GO:0004222	metalloendopeptidase activity	25/5268	110/18639	0.227272727272727	0.804126113066887	0.921694918548146	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	6/5268	32/18639	0.1875	0.663404043280182	0.923427972139001	1
GO:0042910	xenobiotic transmembrane transporter activity	6/5268	32/18639	0.1875	0.663404043280182	0.923427972139001	1
GO:0019842	vitamin binding	35/5268	150/18639	0.233333333333333	0.825569476082005	0.9269242502982	1
GO:0050661	NADP binding	11/5268	54/18639	0.203703703703704	0.720735256896988	0.929342826570147	1
GO:0051119	sugar transmembrane transporter activity	5/5268	28/18639	0.178571428571429	0.631813374552555	0.930311102526214	1
GO:0051537	2 iron, 2 sulfur cluster binding	5/5268	28/18639	0.178571428571429	0.631813374552555	0.930311102526214	1
GO:0004180	carboxypeptidase activity	9/5268	46/18639	0.195652173913043	0.692247697335842	0.934684785168387	1
GO:1901682	sulfur compound transmembrane transporter activity	13/5268	63/18639	0.206349206349206	0.730095455038507	0.935426512286186	1
GO:0005229	intracellularly calcium-gated chloride channel activity	3/5268	19/18639	0.157894736842105	0.558656036446469	0.93648591422592	1
GO:0008381	mechanosensitive monoatomic ion channel activity	3/5268	19/18639	0.157894736842105	0.558656036446469	0.93648591422592	1
GO:0141147	intracellularly calcium-gated channel activity	3/5268	19/18639	0.157894736842105	0.558656036446469	0.93648591422592	1
GO:0030296	protein tyrosine kinase activator activity	6/5268	33/18639	0.181818181818182	0.64330089045351	0.936490456523214	1
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	12/5268	59/18639	0.203389830508475	0.719624724914096	0.937151789466453	1
GO:0004065	arylsulfatase activity	2/5268	14/18639	0.142857142857143	0.505450699642044	0.937788791724962	1
GO:0005313	L-glutamate transmembrane transporter activity	2/5268	14/18639	0.142857142857143	0.505450699642044	0.937788791724962	1
GO:0008331	high voltage-gated calcium channel activity	2/5268	14/18639	0.142857142857143	0.505450699642044	0.937788791724962	1
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	2/5268	14/18639	0.142857142857143	0.505450699642044	0.937788791724962	1
GO:1901474	azole transmembrane transporter activity	2/5268	14/18639	0.142857142857143	0.505450699642044	0.937788791724962	1
GO:0042056	chemoattractant activity	8/5268	42/18639	0.19047619047619	0.673934266189391	0.938207970199871	1
GO:0019955	cytokine binding	33/5268	144/18639	0.229166666666667	0.810827164009112	0.938647582157305	1
GO:0004806	triacylglycerol lipase activity	4/5268	24/18639	0.166666666666667	0.589692482915718	0.939028920280138	1
GO:0019957	C-C chemokine binding	4/5268	24/18639	0.166666666666667	0.589692482915718	0.939028920280138	1
GO:0042625	ATPase-coupled ion transmembrane transporter activity	4/5268	24/18639	0.166666666666667	0.589692482915718	0.939028920280138	1
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	4/5268	24/18639	0.166666666666667	0.589692482915718	0.939028920280138	1
GO:0046961	proton-transporting ATPase activity, rotational mechanism	4/5268	24/18639	0.166666666666667	0.589692482915718	0.939028920280138	1
GO:0005109	frizzled binding	7/5268	38/18639	0.184210526315789	0.651765375854214	0.942444531606941	1
GO:0005501	retinoid binding	7/5268	38/18639	0.184210526315789	0.651765375854214	0.942444531606941	1
GO:0019840	isoprenoid binding	7/5268	38/18639	0.184210526315789	0.651765375854214	0.942444531606941	1
GO:0004181	metallocarboxypeptidase activity	5/5268	29/18639	0.172413793103448	0.610026706464535	0.943040291077924	1
GO:0051861	glycolipid binding	5/5268	29/18639	0.172413793103448	0.610026706464535	0.943040291077924	1
GO:0030170	pyridoxal phosphate binding	11/5268	56/18639	0.196428571428571	0.69499471200781	0.947865729212907	1
GO:0016798	hydrolase activity, acting on glycosyl bonds	29/5268	130/18639	0.223076923076923	0.789280707902576	0.949198696299534	1
GO:0042562	hormone binding	20/5268	94/18639	0.212765957446809	0.752798914360491	0.951082874580503	1
GO:0001848	complement binding	4/5268	25/18639	0.16	0.566104783599089	0.951088830642405	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	4/5268	25/18639	0.16	0.566104783599089	0.951088830642405	1
GO:0015116	sulfate transmembrane transporter activity	2/5268	15/18639	0.133333333333333	0.471753986332574	0.952683824443285	1
GO:0030553	cGMP binding	2/5268	15/18639	0.133333333333333	0.471753986332574	0.952683824443285	1
GO:0034483	heparan sulfate sulfotransferase activity	2/5268	15/18639	0.133333333333333	0.471753986332574	0.952683824443285	1
GO:0022839	monoatomic ion-gated channel activity	5/5268	30/18639	0.166666666666667	0.589692482915718	0.953630291955711	1
GO:0015085	calcium ion transmembrane transporter activity	33/5268	147/18639	0.224489795918367	0.794279670866069	0.95455199269223	1
GO:0004601	peroxidase activity	11/5268	57/18639	0.192982456140351	0.682801822323462	0.955418773306265	1
GO:0030547	signaling receptor inhibitor activity	8/5268	44/18639	0.181818181818182	0.64330089045351	0.956399322727317	1
GO:0008081	phosphoric diester hydrolase activity	18/5268	87/18639	0.206896551724138	0.732032047757442	0.958261662605479	1
GO:0046982	protein heterodimerization activity	90/5268	369/18639	0.24390243902439	0.862964609144952	0.959508356604726	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	5/5268	31/18639	0.161290322580645	0.570670144757146	0.962393678884799	1
GO:0004955	prostaglandin receptor activity	1/5268	10/18639	0.1	0.353815489749431	0.963942174240355	1
GO:0005337	nucleoside transmembrane transporter activity	1/5268	10/18639	0.1	0.353815489749431	0.963942174240355	1
GO:0005345	purine nucleobase transmembrane transporter activity	1/5268	10/18639	0.1	0.353815489749431	0.963942174240355	1
GO:0008239	dipeptidyl-peptidase activity	1/5268	10/18639	0.1	0.353815489749431	0.963942174240355	1
GO:0015187	glycine transmembrane transporter activity	1/5268	10/18639	0.1	0.353815489749431	0.963942174240355	1
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/5268	10/18639	0.1	0.353815489749431	0.963942174240355	1
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/5268	10/18639	0.1	0.353815489749431	0.963942174240355	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/5268	10/18639	0.1	0.353815489749431	0.963942174240355	1
GO:0032052	bile acid binding	1/5268	10/18639	0.1	0.353815489749431	0.963942174240355	1
GO:0043121	neurotrophin binding	1/5268	10/18639	0.1	0.353815489749431	0.963942174240355	1
GO:0043208	glycosphingolipid binding	1/5268	10/18639	0.1	0.353815489749431	0.963942174240355	1
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/5268	10/18639	0.1	0.353815489749431	0.963942174240355	1
GO:0070739	protein-glutamic acid ligase activity	1/5268	10/18639	0.1	0.353815489749431	0.963942174240355	1
GO:0070740	tubulin-glutamic acid ligase activity	1/5268	10/18639	0.1	0.353815489749431	0.963942174240355	1
GO:0016500	protein-hormone receptor activity	13/5268	67/18639	0.194029850746269	0.686507666677999	0.964114659188592	1
GO:0005149	interleukin-1 receptor binding	2/5268	16/18639	0.125	0.442269362186788	0.96413033626279	1
GO:0016722	oxidoreductase activity, acting on metal ions	2/5268	16/18639	0.125	0.442269362186788	0.96413033626279	1
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/5268	16/18639	0.125	0.442269362186788	0.96413033626279	1
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	2/5268	16/18639	0.125	0.442269362186788	0.96413033626279	1
GO:0015175	neutral L-amino acid transmembrane transporter activity	7/5268	41/18639	0.170731707317073	0.604075226401467	0.967071057694485	1
GO:0015459	potassium channel regulator activity	11/5268	59/18639	0.186440677966102	0.659655997837921	0.967678879186732	1
GO:0008395	steroid hydroxylase activity	4/5268	27/18639	0.148148148148148	0.524171095925082	0.968886264510996	1
GO:0015377	chloride:monoatomic cation symporter activity	3/5268	22/18639	0.136363636363636	0.482475667840133	0.969552679627071	1
GO:0030021	extracellular matrix structural constituent conferring compression resistance	3/5268	22/18639	0.136363636363636	0.482475667840133	0.969552679627071	1
GO:0015106	bicarbonate transmembrane transporter activity	5/5268	32/18639	0.15625	0.552836702733485	0.969609550504391	1
GO:0015101	organic cation transmembrane transporter activity	16/5268	81/18639	0.197530864197531	0.698894794566776	0.969969043716599	1
GO:0022829	wide pore channel activity	6/5268	37/18639	0.162162162162162	0.57375484824232	0.971051623013748	1
GO:0009881	photoreceptor activity	2/5268	17/18639	0.117647058823529	0.416253517352271	0.972887453569238	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	2/5268	17/18639	0.117647058823529	0.416253517352271	0.972887453569238	1
GO:0030548	acetylcholine receptor regulator activity	2/5268	17/18639	0.117647058823529	0.416253517352271	0.972887453569238	1
GO:0070492	oligosaccharide binding	2/5268	17/18639	0.117647058823529	0.416253517352271	0.972887453569238	1
GO:0001851	complement component C3b binding	1/5268	11/18639	0.0909090909090909	0.321650445226755	0.974138783081506	1
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/5268	11/18639	0.0909090909090909	0.321650445226755	0.974138783081506	1
GO:0004954	prostanoid receptor activity	1/5268	11/18639	0.0909090909090909	0.321650445226755	0.974138783081506	1
GO:0008046	axon guidance receptor activity	1/5268	11/18639	0.0909090909090909	0.321650445226755	0.974138783081506	1
GO:0008503	benzodiazepine receptor activity	1/5268	11/18639	0.0909090909090909	0.321650445226755	0.974138783081506	1
GO:0010854	adenylate cyclase regulator activity	1/5268	11/18639	0.0909090909090909	0.321650445226755	0.974138783081506	1
GO:0015205	nucleobase transmembrane transporter activity	1/5268	11/18639	0.0909090909090909	0.321650445226755	0.974138783081506	1
GO:0016594	glycine binding	1/5268	11/18639	0.0909090909090909	0.321650445226755	0.974138783081506	1
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/5268	11/18639	0.0909090909090909	0.321650445226755	0.974138783081506	1
GO:0048407	platelet-derived growth factor binding	1/5268	11/18639	0.0909090909090909	0.321650445226755	0.974138783081506	1
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/5268	11/18639	0.0909090909090909	0.321650445226755	0.974138783081506	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/5268	11/18639	0.0909090909090909	0.321650445226755	0.974138783081506	1
GO:0050698	proteoglycan sulfotransferase activity	4/5268	28/18639	0.142857142857143	0.505450699642044	0.975315458175126	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	18/5268	91/18639	0.197802197802198	0.699854814888983	0.975813799305203	1
GO:0005212	structural constituent of eye lens	3/5268	23/18639	0.130434782608696	0.461498464890562	0.976338194253431	1
GO:0022804	active transmembrane transporter activity	111/5268	457/18639	0.242888402625821	0.859376791295116	0.976472801361656	1
GO:0015026	coreceptor activity	11/5268	61/18639	0.180327868852459	0.638027932335039	0.976821223612905	1
GO:0061134	peptidase regulator activity	51/5268	226/18639	0.225663716814159	0.798433184832786	0.978493144282531	1
GO:0033293	monocarboxylic acid binding	15/5268	79/18639	0.189873417721519	0.671801562815375	0.978572256708406	1
GO:0004970	glutamate-gated receptor activity	2/5268	18/18639	0.111111111111111	0.393128321943812	0.979560746578394	1
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	2/5268	18/18639	0.111111111111111	0.393128321943812	0.979560746578394	1
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	2/5268	18/18639	0.111111111111111	0.393128321943812	0.979560746578394	1
GO:0099602	neurotransmitter receptor regulator activity	2/5268	18/18639	0.111111111111111	0.393128321943812	0.979560746578394	1
GO:0015020	glucuronosyltransferase activity	5/5268	34/18639	0.147058823529412	0.520316896690339	0.980349891283313	1
GO:0008146	sulfotransferase activity	9/5268	53/18639	0.169811320754717	0.600818756178278	0.980606781643359	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	25/5268	122/18639	0.204918032786885	0.725031741289817	0.980632230860859	1
GO:0004126	cytidine deaminase activity	1/5268	12/18639	0.0833333333333333	0.294846241457859	0.981452337447333	1
GO:0010853	cyclase activator activity	1/5268	12/18639	0.0833333333333333	0.294846241457859	0.981452337447333	1
GO:0015166	polyol transmembrane transporter activity	1/5268	12/18639	0.0833333333333333	0.294846241457859	0.981452337447333	1
GO:0015295	solute:proton symporter activity	3/5268	24/18639	0.125	0.442269362186788	0.98166809053533	1
GO:0005201	extracellular matrix structural constituent	36/5268	168/18639	0.214285714285714	0.758176049463065	0.982548377480687	1
GO:0042626	ATPase-coupled transmembrane transporter activity	19/5268	98/18639	0.193877551020408	0.685968806657059	0.98362538896673	1
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	9/5268	54/18639	0.166666666666667	0.589692482915718	0.983881484603943	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	4/5268	30/18639	0.133333333333333	0.471753986332574	0.984610129980673	1
GO:0048019	receptor antagonist activity	4/5268	30/18639	0.133333333333333	0.471753986332574	0.984610129980673	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	2/5268	19/18639	0.105263157894737	0.37243735763098	0.984628373913979	1
GO:0016918	retinal binding	2/5268	19/18639	0.105263157894737	0.37243735763098	0.984628373913979	1
GO:0022840	leak channel activity	2/5268	19/18639	0.105263157894737	0.37243735763098	0.984628373913979	1
GO:0022842	narrow pore channel activity	2/5268	19/18639	0.105263157894737	0.37243735763098	0.984628373913979	1
GO:0042834	peptidoglycan binding	2/5268	19/18639	0.105263157894737	0.37243735763098	0.984628373913979	1
GO:0004465	lipoprotein lipase activity	1/5268	13/18639	0.0769230769230769	0.272165761345716	0.986697899605891	1
GO:0005542	folic acid binding	1/5268	13/18639	0.0769230769230769	0.272165761345716	0.986697899605891	1
GO:0008035	high-density lipoprotein particle binding	1/5268	13/18639	0.0769230769230769	0.272165761345716	0.986697899605891	1
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/5268	13/18639	0.0769230769230769	0.272165761345716	0.986697899605891	1
GO:0089720	caspase binding	1/5268	13/18639	0.0769230769230769	0.272165761345716	0.986697899605891	1
GO:0015291	secondary active transmembrane transporter activity	65/5268	287/18639	0.226480836236934	0.801324279920313	0.987311326520026	1
GO:0005272	sodium channel activity	8/5268	51/18639	0.156862745098039	0.555004689803028	0.988323234751029	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	2/5268	20/18639	0.1	0.353815489749431	0.988464717192857	1
GO:0005326	neurotransmitter transmembrane transporter activity	2/5268	20/18639	0.1	0.353815489749431	0.988464717192857	1
GO:0015145	monosaccharide transmembrane transporter activity	3/5268	26/18639	0.115384615384615	0.408248642018574	0.989088463937277	1
GO:0019865	immunoglobulin binding	3/5268	26/18639	0.115384615384615	0.408248642018574	0.989088463937277	1
GO:0030247	polysaccharide binding	3/5268	26/18639	0.115384615384615	0.408248642018574	0.989088463937277	1
GO:0005262	calcium channel activity	26/5268	131/18639	0.198473282442748	0.70222921629658	0.989644159162611	1
GO:0005504	fatty acid binding	7/5268	47/18639	0.148936170212766	0.526959240052343	0.990084554690347	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	8/5268	52/18639	0.153846153846154	0.544331522691432	0.990431242921584	1
GO:0005344	oxygen carrier activity	1/5268	14/18639	0.0714285714285714	0.252725349821022	0.990460138673654	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	26/5268	132/18639	0.196969696969697	0.696909297991303	0.990939156638998	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	3/5268	27/18639	0.111111111111111	0.393128321943812	0.991613738865562	1
GO:0004089	carbonate dehydratase activity	1/5268	15/18639	0.0666666666666667	0.235876993166287	0.993158446832967	1
GO:0004953	icosanoid receptor activity	1/5268	15/18639	0.0666666666666667	0.235876993166287	0.993158446832967	1
GO:0008242	omega peptidase activity	1/5268	15/18639	0.0666666666666667	0.235876993166287	0.993158446832967	1
GO:0005243	gap junction channel activity	2/5268	22/18639	0.0909090909090909	0.321650445226755	0.99354165148407	1
GO:0005126	cytokine receptor binding	60/5268	275/18639	0.218181818181818	0.771961068544212	0.99403959850601	1
GO:1901681	sulfur compound binding	60/5268	275/18639	0.218181818181818	0.771961068544212	0.99403959850601	1
GO:0015144	carbohydrate transmembrane transporter activity	5/5268	40/18639	0.125	0.442269362186788	0.995039459862731	1
GO:0031406	carboxylic acid binding	38/5268	187/18639	0.203208556149733	0.718983348153923	0.995057781223885	1
GO:0015378	sodium:chloride symporter activity	1/5268	16/18639	0.0625	0.221134681093394	0.995093654204312	1
GO:0019841	retinol binding	1/5268	16/18639	0.0625	0.221134681093394	0.995093654204312	1
GO:0008514	organic anion transmembrane transporter activity	58/5268	269/18639	0.215613382899628	0.762873546671635	0.995168213103767	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	2/5268	23/18639	0.0869565217391304	0.307665643260374	0.995180075982226	1
GO:0005283	amino acid:sodium symporter activity	2/5268	23/18639	0.0869565217391304	0.307665643260374	0.995180075982226	1
GO:0016493	C-C chemokine receptor activity	2/5268	23/18639	0.0869565217391304	0.307665643260374	0.995180075982226	1
GO:0016917	GABA receptor activity	2/5268	23/18639	0.0869565217391304	0.307665643260374	0.995180075982226	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	11/5268	70/18639	0.157142857142857	0.555995769606248	0.995393137556064	1
GO:0005506	iron ion binding	30/5268	154/18639	0.194805194805195	0.689250954057332	0.995408763671541	1
GO:0015171	amino acid transmembrane transporter activity	18/5268	102/18639	0.176470588235294	0.624380276028407	0.995417785111051	1
GO:0061135	endopeptidase regulator activity	37/5268	184/18639	0.201086956521739	0.711476800039616	0.995721400816149	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	6/5268	46/18639	0.130434782608696	0.461498464890562	0.99586064997448	1
GO:0043177	organic acid binding	38/5268	189/18639	0.201058201058201	0.711375058755469	0.99613931405554	1
GO:0015149	hexose transmembrane transporter activity	2/5268	24/18639	0.0833333333333333	0.294846241457859	0.99640843829558	1
GO:0055056	D-glucose transmembrane transporter activity	2/5268	24/18639	0.0833333333333333	0.294846241457859	0.99640843829558	1
GO:0045125	bioactive lipid receptor activity	1/5268	17/18639	0.0588235294117647	0.208126758676136	0.996481541744004	1
GO:0045236	CXCR chemokine receptor binding	1/5268	17/18639	0.0588235294117647	0.208126758676136	0.996481541744004	1
GO:0004175	endopeptidase activity	91/5268	405/18639	0.224691358024691	0.794992828819708	0.99681720200068	1
GO:0004620	phospholipase activity	19/5268	109/18639	0.174311926605505	0.616742596810934	0.996959722982413	1
GO:0038187	pattern recognition receptor activity	6/5268	48/18639	0.125	0.442269362186788	0.997384126844455	1
GO:0015373	monoatomic anion:sodium symporter activity	1/5268	18/18639	0.0555555555555556	0.196564160971906	0.997476882636099	1
GO:0022851	GABA-gated chloride ion channel activity	1/5268	18/18639	0.0555555555555556	0.196564160971906	0.997476882636099	1
GO:0032393	MHC class I receptor activity	1/5268	18/18639	0.0555555555555556	0.196564160971906	0.997476882636099	1
GO:0001637	G protein-coupled chemoattractant receptor activity	2/5268	26/18639	0.0769230769230769	0.272165761345716	0.998014203063781	1
GO:0004950	chemokine receptor activity	2/5268	26/18639	0.0769230769230769	0.272165761345716	0.998014203063781	1
GO:0008066	glutamate receptor activity	2/5268	26/18639	0.0769230769230769	0.272165761345716	0.998014203063781	1
GO:0004890	GABA-A receptor activity	1/5268	19/18639	0.0526315789473684	0.18621867881549	0.998190688676216	1
GO:0034987	immunoglobulin receptor binding	1/5268	19/18639	0.0526315789473684	0.18621867881549	0.998190688676216	1
GO:0048020	CCR chemokine receptor binding	6/5268	50/18639	0.12	0.424578587699317	0.998360266601914	1
GO:0008083	growth factor activity	30/5268	162/18639	0.185185185185185	0.655213869906353	0.998495945261269	1
GO:0005104	fibroblast growth factor receptor binding	2/5268	27/18639	0.0740740740740741	0.262085547962541	0.998526240199638	1
GO:0015252	proton channel activity	2/5268	27/18639	0.0740740740740741	0.262085547962541	0.998526240199638	1
GO:0001614	purinergic nucleotide receptor activity	1/5268	20/18639	0.05	0.176907744874715	0.998702581912183	1
GO:0010851	cyclase regulator activity	1/5268	20/18639	0.05	0.176907744874715	0.998702581912183	1
GO:0016502	nucleotide receptor activity	1/5268	20/18639	0.05	0.176907744874715	0.998702581912183	1
GO:0030627	pre-mRNA 5'-splice site binding	1/5268	20/18639	0.05	0.176907744874715	0.998702581912183	1
GO:0004497	monooxygenase activity	17/5268	106/18639	0.160377358490566	0.567439936390596	0.998925180395161	1
GO:0005343	organic acid:sodium symporter activity	3/5268	35/18639	0.0857142857142857	0.303270419785226	0.999050681909454	1
GO:0015125	bile acid transmembrane transporter activity	1/5268	21/18639	0.0476190476190476	0.168483566547348	0.999069669214756	1
GO:0016298	lipase activity	22/5268	130/18639	0.169230769230769	0.598764674960575	0.999109619897161	1
GO:0005416	amino acid:monoatomic cation symporter activity	2/5268	29/18639	0.0689655172413793	0.244010682585814	0.999191051532698	1
GO:0046943	carboxylic acid transmembrane transporter activity	35/5268	188/18639	0.186170212765957	0.658699050065429	0.999191897217047	1
GO:0005342	organic acid transmembrane transporter activity	35/5268	189/18639	0.185185185185185	0.655213869906353	0.999298956546971	1
GO:0033691	sialic acid binding	1/5268	22/18639	0.0454545454545455	0.160825222613378	0.999332908154313	1
GO:0008201	heparin binding	31/5268	172/18639	0.180232558139535	0.637690708269322	0.999342836048303	1
GO:0003730	mRNA 3'-UTR binding	52/5268	262/18639	0.198473282442748	0.70222921629658	0.99935686372356	1
GO:0004867	serine-type endopeptidase inhibitor activity	14/5268	95/18639	0.147368421052632	0.521412300683371	0.999405156122891	1
GO:0005245	voltage-gated calcium channel activity	4/5268	43/18639	0.0930232558139535	0.329130688139005	0.999434412139425	1
GO:0046906	tetrapyrrole binding	26/5268	152/18639	0.171052631578947	0.605210706150342	0.999533041446015	1
GO:0030020	extracellular matrix structural constituent conferring tensile strength	4/5268	44/18639	0.0909090909090909	0.321650445226755	0.99956687650766	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/5268	24/18639	0.0416666666666667	0.147423120728929	0.999657031294673	1
GO:0005253	monoatomic anion channel activity	15/5268	103/18639	0.145631067961165	0.515265276334122	0.999678109982558	1
GO:0030414	peptidase inhibitor activity	29/5268	169/18639	0.171597633136095	0.607139006078904	0.999734464597263	1
GO:0015271	outward rectifier potassium channel activity	1/5268	25/18639	0.04	0.141526195899772	0.999754090609186	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/5268	25/18639	0.04	0.141526195899772	0.999754090609186	1
GO:0004866	endopeptidase inhibitor activity	27/5268	161/18639	0.167701863354037	0.593355169145008	0.99977479821981	1
GO:0099095	ligand-gated monoatomic anion channel activity	4/5268	47/18639	0.0851063829787234	0.301119565744196	0.999807104730832	1
GO:0001664	G protein-coupled receptor binding	58/5268	297/18639	0.195286195286195	0.690952808264881	0.999811348253158	1
GO:0020037	heme binding	22/5268	142/18639	0.154929577464789	0.548164843273766	0.999887843138748	1
GO:0005539	glycosaminoglycan binding	44/5268	242/18639	0.181818181818182	0.64330089045351	0.999904024434227	1
GO:0005242	inward rectifier potassium channel activity	1/5268	28/18639	0.0357142857142857	0.126362674910511	0.999909367968426	1
GO:0008509	monoatomic anion transmembrane transporter activity	23/5268	149/18639	0.154362416107383	0.546158138539389	0.999925820429685	1
GO:0005184	neuropeptide hormone activity	1/5268	31/18639	0.032258064516129	0.114134028951429	0.999966603157883	1
GO:0030246	carbohydrate binding	51/5268	280/18639	0.182142857142857	0.644449642043606	0.999967258429001	1
GO:0042379	chemokine receptor binding	7/5268	72/18639	0.0972222222222222	0.343987281700835	0.999970194993202	1
GO:0071855	neuropeptide receptor binding	2/5268	40/18639	0.05	0.176907744874715	0.999971950043526	1
GO:0015081	sodium ion transmembrane transporter activity	25/5268	164/18639	0.152439024390244	0.539352880715595	0.999972853688375	1
GO:0160041	neuropeptide activity	1/5268	32/18639	0.03125	0.110567340546697	0.999976057938852	1
GO:0015294	solute:monoatomic cation symporter activity	15/5268	116/18639	0.129310344827586	0.457520029848402	0.999976844565316	1
GO:0015293	symporter activity	21/5268	146/18639	0.143835616438356	0.508912690735482	0.999978021220686	1
GO:0015370	solute:sodium symporter activity	8/5268	79/18639	0.10126582278481	0.358294166834866	0.999978342485886	1
GO:0019825	oxygen binding	1/5268	34/18639	0.0294117647058824	0.104063379338068	0.99998769600497	1
GO:0017171	serine hydrolase activity	31/5268	198/18639	0.156565656565657	0.553953544557189	0.999990398857407	1
GO:0015103	inorganic anion transmembrane transporter activity	24/5268	165/18639	0.145454545454545	0.514640712362808	0.999990657891194	1
GO:0008236	serine-type peptidase activity	30/5268	194/18639	0.154639175257732	0.547137355282625	0.999991473289715	1
GO:0005254	chloride channel activity	8/5268	83/18639	0.0963855421686747	0.34102697807174	0.999991944003557	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/5268	36/18639	0.0277777777777778	0.0982820804859529	0.9999936774266	1
GO:0008009	chemokine activity	2/5268	45/18639	0.0444444444444444	0.157251328777525	0.999994068952131	1
GO:0004252	serine-type endopeptidase activity	25/5268	176/18639	0.142045454545455	0.502578820666805	0.999997105750572	1
GO:0015108	chloride transmembrane transporter activity	14/5268	121/18639	0.115702479338843	0.409373293924961	0.99999747665216	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	3/5268	56/18639	0.0535714285714286	0.189544012365766	0.999997866281455	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	2/5268	53/18639	0.0377358490566038	0.133515279150728	0.999999517721732	1
GO:0022824	transmitter-gated monoatomic ion channel activity	3/5268	63/18639	0.0476190476190476	0.168483566547348	0.999999740189769	1
GO:0022835	transmitter-gated channel activity	3/5268	63/18639	0.0476190476190476	0.168483566547348	0.999999740189769	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	4/5268	73/18639	0.0547945205479452	0.193871501232565	0.999999880083463	1
GO:0099094	ligand-gated monoatomic cation channel activity	14/5268	136/18639	0.102941176470588	0.364221827683237	0.999999920718252	1
GO:0098960	postsynaptic neurotransmitter receptor activity	3/5268	69/18639	0.0434782608695652	0.153832821630187	0.999999958084574	1
GO:0008528	G protein-coupled peptide receptor activity	11/5268	122/18639	0.0901639344262295	0.319013966167519	0.999999963117097	1
GO:0003823	antigen binding	20/5268	174/18639	0.114942528735632	0.406684470976357	0.999999977165237	1
GO:0004896	cytokine receptor activity	6/5268	96/18639	0.0625	0.221134681093394	0.999999991107899	1
GO:0046873	metal ion transmembrane transporter activity	77/5268	450/18639	0.171111111111111	0.60541761579347	0.999999991275265	1
GO:0001653	peptide receptor activity	11/5268	128/18639	0.0859375	0.304060186503417	0.999999991929849	1
GO:0030594	neurotransmitter receptor activity	4/5268	97/18639	0.0412371134020619	0.145903294742033	0.99999999990815	1
GO:0015079	potassium ion transmembrane transporter activity	13/5268	160/18639	0.08125	0.287475085421412	0.999999999951807	1
GO:0015276	ligand-gated monoatomic ion channel activity	17/5268	186/18639	0.0913978494623656	0.323379748695716	0.999999999972686	1
GO:0022834	ligand-gated channel activity	17/5268	188/18639	0.0904255319148936	0.319939538603208	0.999999999983349	1
GO:0005125	cytokine activity	25/5268	234/18639	0.106837606837607	0.37800800186905	0.999999999986979	1
GO:0140375	immune receptor activity	11/5268	156/18639	0.0705128205128205	0.249485281233573	0.999999999994902	1
GO:0022832	voltage-gated channel activity	14/5268	175/18639	0.08	0.283052391799544	0.999999999995192	1
GO:0005261	monoatomic cation channel activity	44/5268	341/18639	0.129032258064516	0.456536115805717	0.999999999997677	1
GO:0005179	hormone activity	7/5268	132/18639	0.053030303030303	0.187629426382274	0.999999999997789	1
GO:0005244	voltage-gated monoatomic ion channel activity	13/5268	173/18639	0.0751445086705202	0.265872911372404	0.999999999998395	1
GO:0005267	potassium channel activity	5/5268	124/18639	0.0403225806451613	0.142667536189286	0.99999999999972	1
GO:0005249	voltage-gated potassium channel activity	2/5268	98/18639	0.0204081632653061	0.0722072428060062	0.999999999999737	1
GO:0022843	voltage-gated monoatomic cation channel activity	6/5268	143/18639	0.041958041958042	0.148454051643118	0.99999999999999	1
GO:0005216	monoatomic ion channel activity	58/5268	448/18639	0.129464285714286	0.458064696550602	0.999999999999999	1
GO:0022836	gated channel activity	29/5268	318/18639	0.0911949685534591	0.322661924614261	1	1
GO:0030371	translation repressor activity	12/5268	329/18639	0.0364741641337386	0.129051242461798	1	1
GO:0045182	translation regulator activity	19/5268	356/18639	0.0533707865168539	0.18883410969773	1	1