ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003779 actin binding 110/1774 443/18639 0.248306997742664 2.60890311777086 1.4740744725432e-21 1.80574122886542e-18 GO:0106310 protein serine kinase activity 86/1774 361/18639 0.238227146814404 2.50299649913962 6.07690801583615e-16 3.72210615969964e-13 GO:0004674 protein serine/threonine kinase activity 96/1774 433/18639 0.221709006928406 2.32944429545579 1.71203058399494e-15 6.99079155131265e-13 GO:0030695 GTPase regulator activity 94/1774 489/18639 0.192229038854806 2.01970521714471 2.28744301420339e-11 6.30432972327217e-09 GO:0060589 nucleoside-triphosphatase regulator activity 94/1774 490/18639 0.191836734693878 2.01558336976279 2.57319580541721e-11 6.30432972327217e-09 GO:0035403 histone H3T6 kinase activity 55/1774 247/18639 0.222672064777328 2.33956291735322 1.59521137595323e-09 3.25688989257117e-07 GO:0140857 histone H3T45 kinase activity 54/1774 246/18639 0.219512195121951 2.30636291143069 3.83607338575799e-09 3.97825927285136e-07 GO:0004679 AMP-activated protein kinase activity 54/1774 248/18639 0.217741935483871 2.28776321053206 5.18666193967796e-09 3.97825927285136e-07 GO:0051015 actin filament binding 48/1774 209/18639 0.229665071770335 2.41303679409655 6.00665149661591e-09 3.97825927285136e-07 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 53/1774 243/18639 0.218106995884774 2.29159881414673 6.74937475126195e-09 3.97825927285136e-07 GO:0005085 guanyl-nucleotide exchange factor activity 51/1774 230/18639 0.221739130434783 2.32976079603941 7.21722726397729e-09 3.97825927285136e-07 GO:0004676 3-phosphoinositide-dependent protein kinase activity 53/1774 245/18639 0.216326530612245 2.27289188505165 9.09316405223168e-09 3.97825927285136e-07 GO:0004711 ribosomal protein S6 kinase activity 53/1774 245/18639 0.216326530612245 2.27289188505165 9.09316405223168e-09 3.97825927285136e-07 GO:0035175 histone H3S10 kinase activity 53/1774 245/18639 0.216326530612245 2.27289188505165 9.09316405223168e-09 3.97825927285136e-07 GO:0035979 histone H2AXS139 kinase activity 53/1774 245/18639 0.216326530612245 2.27289188505165 9.09316405223168e-09 3.97825927285136e-07 GO:0044022 histone H3S28 kinase activity 53/1774 245/18639 0.216326530612245 2.27289188505165 9.09316405223168e-09 3.97825927285136e-07 GO:0044023 histone H4S1 kinase activity 53/1774 245/18639 0.216326530612245 2.27289188505165 9.09316405223168e-09 3.97825927285136e-07 GO:0044024 histone H2AS1 kinase activity 53/1774 245/18639 0.216326530612245 2.27289188505165 9.09316405223168e-09 3.97825927285136e-07 GO:0044025 histone H2BS14 kinase activity 53/1774 245/18639 0.216326530612245 2.27289188505165 9.09316405223168e-09 3.97825927285136e-07 GO:0072354 histone H3T3 kinase activity 53/1774 245/18639 0.216326530612245 2.27289188505165 9.09316405223168e-09 3.97825927285136e-07 GO:0072371 histone H2AS121 kinase activity 53/1774 245/18639 0.216326530612245 2.27289188505165 9.09316405223168e-09 3.97825927285136e-07 GO:0072518 Rho-dependent protein serine/threonine kinase activity 53/1774 245/18639 0.216326530612245 2.27289188505165 9.09316405223168e-09 3.97825927285136e-07 GO:0140823 histone H2BS36 kinase activity 53/1774 245/18639 0.216326530612245 2.27289188505165 9.09316405223168e-09 3.97825927285136e-07 GO:0140855 histone H3S57 kinase activity 53/1774 245/18639 0.216326530612245 2.27289188505165 9.09316405223168e-09 3.97825927285136e-07 GO:0140995 histone H2A kinase activity 53/1774 245/18639 0.216326530612245 2.27289188505165 9.09316405223168e-09 3.97825927285136e-07 GO:0140997 histone H4 kinase activity 53/1774 245/18639 0.216326530612245 2.27289188505165 9.09316405223168e-09 3.97825927285136e-07 GO:0140998 histone H2B kinase activity 53/1774 245/18639 0.216326530612245 2.27289188505165 9.09316405223168e-09 3.97825927285136e-07 GO:1990244 histone H2AT120 kinase activity 53/1774 245/18639 0.216326530612245 2.27289188505165 9.09316405223168e-09 3.97825927285136e-07 GO:0004677 DNA-dependent protein kinase activity 53/1774 246/18639 0.215447154471545 2.26365248714494 1.05368210746312e-08 4.45089855738733e-07 GO:0035402 histone H3T11 kinase activity 53/1774 247/18639 0.214574898785425 2.25448790217674 1.21961501980066e-08 4.98009466418602e-07 GO:0005516 calmodulin binding 47/1774 207/18639 0.227053140096618 2.38559384343905 1.26666661179222e-08 4.98294419943237e-07 GO:0031994 insulin-like growth factor I binding 10/1774 13/18639 0.769230769230769 8.08212644176568 1.30166705617825e-08 4.98294419943237e-07 GO:0045296 cadherin binding 64/1774 334/18639 0.191616766467066 2.01327221543384 4.08547361627425e-08 1.51657732725332e-06 GO:0140996 histone H3 kinase activity 67/1774 357/18639 0.187675070028011 1.9718577397137 4.58019874811843e-08 1.65021866660149e-06 GO:0035173 histone kinase activity 67/1774 360/18639 0.186111111111111 1.95542559188275 6.39351267363269e-08 2.23772943577144e-06 GO:0141003 histone H2AX kinase activity 65/1774 354/18639 0.18361581920904 1.9292081478226 1.67912439947027e-07 5.71368719264188e-06 GO:0005520 insulin-like growth factor binding 11/1774 19/18639 0.578947368421053 6.08286358511838 2.06764608557227e-07 6.84558501304334e-06 GO:0051393 alpha-actinin binding 13/1774 28/18639 0.464285714285714 4.87814060235143 4.79079349253225e-07 1.54440053377685e-05 GO:0042805 actinin binding 15/1774 37/18639 0.405405405405405 4.25949907066029 5.5434031265248e-07 1.74119713589561e-05 GO:0071889 14-3-3 protein binding 14/1774 33/18639 0.424242424242424 4.45741518909501 6.8150006071453e-07 2.08709393593825e-05 GO:0031267 small GTPase binding 53/1774 283/18639 0.187279151943463 1.96769792168783 1.2176924489529e-06 3.63822743894463e-05 GO:0017124 SH3 domain binding 28/1774 115/18639 0.243478260869565 2.55816871721974 2.51438282028656e-06 7.33361655916912e-05 GO:0051020 GTPase binding 56/1774 315/18639 0.177777777777778 1.86786922209696 3.33548255418759e-06 9.50224681134836e-05 GO:0005178 integrin binding 34/1774 161/18639 0.211180124223602 2.21881980575182 6.94145194280064e-06 0.000193256332498427 GO:0042578 phosphoric ester hydrolase activity 61/1774 363/18639 0.168044077134986 1.76559952295322 8.04882573508437e-06 0.000219106922788408 GO:0015631 tubulin binding 63/1774 385/18639 0.163636363636364 1.71928871579379 1.36842605897395e-05 0.000364417809183281 GO:0003712 transcription coregulator activity 76/1774 495/18639 0.153535353535354 1.6131597827201 1.93061633206682e-05 0.000503192554634437 GO:0051371 muscle alpha-actinin binding 8/1774 15/18639 0.533333333333333 5.60360766629087 2.31180589694924e-05 0.000589992129950588 GO:0005096 GTPase activator activity 47/1774 271/18639 0.173431734317343 1.82220636749772 3.79952122832995e-05 0.000949880307082487 GO:0008307 structural constituent of muscle 13/1774 42/18639 0.30952380952381 3.25209373490095 9.15428531333765e-05 0.00224279990176772 GO:0016791 phosphatase activity 46/1774 273/18639 0.168498168498169 1.77037055391058 9.36662670978399e-05 0.00224982700382067 GO:0008017 microtubule binding 46/1774 276/18639 0.166666666666667 1.7511273957159 0.000122107969690701 0.00287658197829055 GO:0016922 nuclear receptor binding 27/1774 137/18639 0.197080291970803 2.07067619055456 0.000200396034611453 0.0045859845314213 GO:0005543 phospholipid binding 72/1774 497/18639 0.144869215291751 1.52210671015949 0.000202157685466735 0.0045859845314213 GO:0019902 phosphatase binding 34/1774 190/18639 0.178947368421053 1.88015783540023 0.000232683334025512 0.00518249243965913 GO:0005080 protein kinase C binding 14/1774 52/18639 0.269230769230769 2.82874425461799 0.000260804591259676 0.0057051004338054 GO:0008013 beta-catenin binding 22/1774 106/18639 0.207547169811321 2.18064920975942 0.000355780992097076 0.00764617044419154 GO:0017166 vinculin binding 6/1774 12/18639 0.5 5.25338218714769 0.000410721936152959 0.00867473054805818 GO:0051010 microtubule plus-end binding 8/1774 21/18639 0.380952380952381 4.00257690449348 0.000433786581859607 0.00900658580979693 GO:0003774 cytoskeletal motor activity 28/1774 153/18639 0.183006535947712 1.92280655215863 0.000549993946562782 0.0112290430756568 GO:0044389 ubiquitin-like protein ligase binding 49/1774 322/18639 0.152173913043478 1.59885544826234 0.000671204360166399 0.0134791039541613 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 8/1774 23/18639 0.347826086956522 3.65452673888535 0.000879154062106241 0.017370382678712 GO:0031625 ubiquitin protein ligase binding 46/1774 302/18639 0.152317880794702 1.60036808350195 0.000944171084874722 0.0183588822058974 GO:0030331 nuclear estrogen receptor binding 11/1774 40/18639 0.275 2.88936020293123 0.00096446196738545 0.0184604048444871 GO:0005161 platelet-derived growth factor receptor binding 6/1774 14/18639 0.428571428571429 4.50289901755516 0.00112899202498173 0.0209547762212518 GO:0005545 1-phosphatidylinositol binding 6/1774 14/18639 0.428571428571429 4.50289901755516 0.00112899202498173 0.0209547762212518 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 8/1774 24/18639 0.333333333333333 3.50225479143179 0.00120966836738583 0.0217918198536418 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 8/1774 24/18639 0.333333333333333 3.50225479143179 0.00120966836738583 0.0217918198536418 GO:0001968 fibronectin binding 9/1774 30/18639 0.3 3.15202931228861 0.00141216049619941 0.0247128086834897 GO:0051721 protein phosphatase 2A binding 9/1774 30/18639 0.3 3.15202931228861 0.00141216049619941 0.0247128086834897 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 18/1774 89/18639 0.202247191011236 2.12496358131817 0.00160880948852469 0.0273721058811492 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 18/1774 89/18639 0.202247191011236 2.12496358131817 0.00160880948852469 0.0273721058811492 GO:0001222 transcription corepressor binding 12/1774 49/18639 0.244897959183673 2.57308515288866 0.00174355991049233 0.0292583683610014 GO:0140793 histone H2AXY142 phosphatase activity 18/1774 90/18639 0.2 2.10135287485908 0.00183566553692148 0.0303877065233623 GO:0000287 magnesium ion binding 36/1774 230/18639 0.156521739130435 1.64453703249841 0.00199545040147093 0.0325923565573585 GO:0004725 protein tyrosine phosphatase activity 19/1774 98/18639 0.193877551020408 2.03702574603686 0.00203329480033756 0.0327735017159673 GO:0004112 cyclic-nucleotide phosphodiesterase activity 8/1774 26/18639 0.307692307692308 3.23285057670627 0.00216294290483448 0.0339552669667073 GO:0140789 histone phosphatase activity 24/1774 136/18639 0.176470588235294 1.85413488958154 0.00219785695964779 0.0339552669667073 GO:0004721 phosphoprotein phosphatase activity 29/1774 175/18639 0.165714285714286 1.74112095345466 0.0022159521225038 0.0339552669667073 GO:0140297 DNA-binding transcription factor binding 66/1774 488/18639 0.135245901639344 1.42099682111372 0.00221748682231558 0.0339552669667073 GO:0035591 signaling adaptor activity 23/1774 129/18639 0.178294573643411 1.87329907448677 0.00234203689563103 0.0354196937919508 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 6/1774 16/18639 0.375 3.94003664036077 0.00254817517701491 0.0376086095402803 GO:0005024 transforming growth factor beta receptor activity 6/1774 16/18639 0.375 3.94003664036077 0.00254817517701491 0.0376086095402803 GO:0035091 phosphatidylinositol binding 42/1774 284/18639 0.147887323943662 1.55381726662115 0.00269576656795019 0.0393132624492736 GO:0004683 calcium/calmodulin-dependent protein kinase activity 8/1774 27/18639 0.296296296296296 3.11311537016159 0.00282054890133871 0.0401815770706322 GO:0005518 collagen binding 15/1774 72/18639 0.208333333333333 2.18890924464487 0.0028209107167954 0.0401815770706322 GO:0042562 hormone binding 18/1774 94/18639 0.191489361702128 2.01193360358848 0.00303063881073937 0.0426727878523647 GO:0031683 G-protein beta/gamma-subunit complex binding 7/1774 22/18639 0.318181818181818 3.34306139182126 0.00330147804314407 0.0452441178849276 GO:0050321 tau-protein kinase activity 7/1774 22/18639 0.318181818181818 3.34306139182126 0.00330147804314407 0.0452441178849276 GO:0005025 transforming growth factor beta receptor activity, type I 5/1774 12/18639 0.416666666666667 4.37781848928974 0.00347179353565975 0.0452441178849276 GO:0005026 transforming growth factor beta receptor activity, type II 5/1774 12/18639 0.416666666666667 4.37781848928974 0.00347179353565975 0.0452441178849276 GO:0016361 activin receptor activity, type I 5/1774 12/18639 0.416666666666667 4.37781848928974 0.00347179353565975 0.0452441178849276 GO:0016362 activin receptor activity, type II 5/1774 12/18639 0.416666666666667 4.37781848928974 0.00347179353565975 0.0452441178849276 GO:0017002 activin receptor activity 5/1774 12/18639 0.416666666666667 4.37781848928974 0.00347179353565975 0.0452441178849276 GO:0051019 mitogen-activated protein kinase binding 8/1774 28/18639 0.285714285714286 3.00193267837011 0.0036240811027732 0.0466611472883156 GO:0008376 acetylgalactosaminyltransferase activity 9/1774 34/18639 0.264705882352941 2.78120233437231 0.00365671031810473 0.0466611472883156 GO:0003713 transcription coactivator activity 38/1774 256/18639 0.1484375 1.55959783680947 0.00391259649449199 0.049411656760337 GO:0016879 ligase activity, forming carbon-nitrogen bonds 11/1774 48/18639 0.229166666666667 2.40780016910936 0.00464822766255872 0.0580728494004512 GO:0019903 protein phosphatase binding 24/1774 144/18639 0.166666666666667 1.7511273957159 0.00470691327895334 0.0580728494004512 GO:0005201 extracellular matrix structural constituent 27/1774 168/18639 0.160714285714286 1.68858713158319 0.00474064076738377 0.0580728494004512 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 6/1774 18/18639 0.333333333333333 3.50225479143179 0.00500341694378988 0.0600900564327706 GO:0070628 proteasome binding 6/1774 18/18639 0.333333333333333 3.50225479143179 0.00500341694378988 0.0600900564327706 GO:0070123 transforming growth factor beta receptor activity, type III 5/1774 13/18639 0.384615384615385 4.04106322088284 0.00520327018999504 0.0618835532305235 GO:0051117 ATPase binding 16/1774 84/18639 0.19047619047619 2.00128845224674 0.0052962092309954 0.0623832337304746 GO:0022839 monoatomic ion-gated channel activity 8/1774 30/18639 0.266666666666667 2.80180383314543 0.00575075211502433 0.067082301739946 GO:0001221 transcription coregulator binding 20/1774 115/18639 0.173913043478261 1.82726336944267 0.00580467264035452 0.067082301739946 GO:0004712 protein serine/threonine/tyrosine kinase activity 10/1774 43/18639 0.232558139534884 2.44343357541753 0.00611543786477222 0.0693649202254256 GO:0048156 tau protein binding 10/1774 43/18639 0.232558139534884 2.44343357541753 0.00611543786477222 0.0693649202254256 GO:0051219 phosphoprotein binding 17/1774 93/18639 0.182795698924731 1.92059133723679 0.00634458252646933 0.0713037944488526 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 6/1774 19/18639 0.315789473684211 3.31792559188275 0.00673201770550934 0.0749701971749904 GO:0070325 lipoprotein particle receptor binding 8/1774 31/18639 0.258064516129032 2.71142306433429 0.00711661573194402 0.0783239642105598 GO:0004709 MAP kinase kinase kinase activity 7/1774 25/18639 0.28 2.94189402480271 0.00722498608636185 0.0783239642105598 GO:0042974 nuclear retinoic acid receptor binding 7/1774 25/18639 0.28 2.94189402480271 0.00722498608636185 0.0783239642105598 GO:0098821 BMP receptor activity 5/1774 14/18639 0.357142857142857 3.75241584796264 0.00746675805944689 0.0802349002001968 GO:0043539 protein serine/threonine kinase activator activity 14/1774 73/18639 0.191780821917808 2.01499590739911 0.00825006253904824 0.0878811009594269 GO:0004879 nuclear receptor activity 12/1774 59/18639 0.203389830508475 2.13696902528042 0.00871913975521834 0.0920771224150212 GO:0030742 GTP-dependent protein binding 6/1774 20/18639 0.3 3.15202931228861 0.00885522324752803 0.0927149442583063 GO:0005227 calcium-activated cation channel activity 7/1774 26/18639 0.269230769230769 2.82874425461799 0.00908994936376671 0.0943659997509679 GO:0005200 structural constituent of cytoskeleton 19/1774 112/18639 0.169642857142857 1.78239752778225 0.00920364221272382 0.0947433757192158 GO:1901981 phosphatidylinositol phosphate binding 28/1774 185/18639 0.151351351351351 1.59021298637984 0.00931222542610369 0.0950623012248085 GO:0016776 phosphotransferase activity, phosphate group as acceptor 9/1774 39/18639 0.230769230769231 2.4246379325297 0.00959204300036446 0.0971095262433592 GO:0050840 extracellular matrix binding 13/1774 67/18639 0.194029850746269 2.03862592337074 0.00969377946069328 0.0973350806504038 GO:0140272 exogenous protein binding 15/1774 82/18639 0.182926829268293 1.92196909285891 0.00991329144730648 0.0985853408267048 GO:0098531 ligand-modulated transcription factor activity 12/1774 60/18639 0.2 2.10135287485908 0.00997925082653991 0.0985853408267048 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 5/1774 15/18639 0.333333333333333 3.50225479143179 0.0103346609930561 0.100475870765824 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 5/1774 15/18639 0.333333333333333 3.50225479143179 0.0103346609930561 0.100475870765824 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 4/1774 10/18639 0.4 4.20270574971815 0.0107383666448639 0.101188454922756 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 4/1774 10/18639 0.4 4.20270574971815 0.0107383666448639 0.101188454922756 GO:0042975 peroxisome proliferator activated receptor binding 4/1774 10/18639 0.4 4.20270574971815 0.0107383666448639 0.101188454922756 GO:0070097 delta-catenin binding 4/1774 10/18639 0.4 4.20270574971815 0.0107383666448639 0.101188454922756 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 15/1774 83/18639 0.180722891566265 1.89881283872808 0.0110650265207984 0.10347066784716 GO:0009931 calcium-dependent protein serine/threonine kinase activity 6/1774 21/18639 0.285714285714286 3.00193267837011 0.0114173469984318 0.105159774985556 GO:0009975 cyclase activity 6/1774 21/18639 0.285714285714286 3.00193267837011 0.0114173469984318 0.105159774985556 GO:0140463 chromatin-protein adaptor activity 11/1774 54/18639 0.203703703703704 2.1402668169861 0.0116335663925867 0.106351633066558 GO:0016758 hexosyltransferase activity 29/1774 197/18639 0.147208121827411 1.54668105002318 0.0119492123078946 0.108225083157598 GO:0019888 protein phosphatase regulator activity 18/1774 107/18639 0.168224299065421 1.76749307231137 0.0120151929056598 0.108225083157598 GO:0016757 glycosyltransferase activity 37/1774 267/18639 0.138576779026217 1.45599356497726 0.0129411750417111 0.115714886321869 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 9/1774 41/18639 0.219512195121951 2.30636291143069 0.0133533296588188 0.117682221813331 GO:0061650 ubiquitin-like protein conjugating enzyme activity 9/1774 41/18639 0.219512195121951 2.30636291143069 0.0133533296588188 0.117682221813331 GO:0046966 nuclear thyroid hormone receptor binding 7/1774 28/18639 0.25 2.62669109357384 0.0138376256665643 0.120536287881808 GO:0004708 MAP kinase kinase activity 5/1774 16/18639 0.3125 3.28336386696731 0.0138739727276204 0.120536287881808 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 46/1774 349/18639 0.131805157593123 1.38484573414781 0.0146977576106322 0.126714654743426 GO:0061631 ubiquitin conjugating enzyme activity 8/1774 35/18639 0.228571428571429 2.40154614269609 0.0151105175903274 0.126714654743426 GO:0016874 ligase activity 25/1774 167/18639 0.149700598802395 1.57286891830769 0.0153051153515552 0.126714654743426 GO:0002162 dystroglycan binding 4/1774 11/18639 0.363636363636364 3.82064159065286 0.0156195207071488 0.126714654743426 GO:0010854 adenylate cyclase regulator activity 4/1774 11/18639 0.363636363636364 3.82064159065286 0.0156195207071488 0.126714654743426 GO:0034056 estrogen response element binding 4/1774 11/18639 0.363636363636364 3.82064159065286 0.0156195207071488 0.126714654743426 GO:0045294 alpha-catenin binding 4/1774 11/18639 0.363636363636364 3.82064159065286 0.0156195207071488 0.126714654743426 GO:0050998 nitric-oxide synthase binding 4/1774 11/18639 0.363636363636364 3.82064159065286 0.0156195207071488 0.126714654743426 GO:0140031 phosphorylation-dependent protein binding 4/1774 11/18639 0.363636363636364 3.82064159065286 0.0156195207071488 0.126714654743426 GO:0180030 inositol phosphate kinase activity 4/1774 11/18639 0.363636363636364 3.82064159065286 0.0156195207071488 0.126714654743426 GO:0046332 SMAD binding 14/1774 79/18639 0.177215189873418 1.86195824354602 0.0162815263453072 0.131216248506588 GO:0008081 phosphoric diester hydrolase activity 15/1774 87/18639 0.172413793103448 1.81151109901644 0.0167537205485067 0.134139265829547 GO:0046965 nuclear retinoid X receptor binding 5/1774 17/18639 0.294117647058824 3.09022481596923 0.0181447890998013 0.144333549657511 GO:0003714 transcription corepressor activity 29/1774 204/18639 0.142156862745098 1.49360866105179 0.0186566257829924 0.147447526349456 GO:0001618 virus receptor activity 14/1774 81/18639 0.172839506172839 1.8159839659276 0.01998359942678 0.149267739620765 GO:0033192 calmodulin-dependent protein phosphatase activity 14/1774 81/18639 0.172839506172839 1.8159839659276 0.01998359942678 0.149267739620765 GO:0140791 histone H2AXS140 phosphatase activity 14/1774 81/18639 0.172839506172839 1.8159839659276 0.01998359942678 0.149267739620765 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 14/1774 81/18639 0.172839506172839 1.8159839659276 0.01998359942678 0.149267739620765 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 14/1774 81/18639 0.172839506172839 1.8159839659276 0.01998359942678 0.149267739620765 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 14/1774 81/18639 0.172839506172839 1.8159839659276 0.01998359942678 0.149267739620765 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 14/1774 81/18639 0.172839506172839 1.8159839659276 0.01998359942678 0.149267739620765 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 14/1774 81/18639 0.172839506172839 1.8159839659276 0.01998359942678 0.149267739620765 GO:1990439 MAP kinase serine/threonine phosphatase activity 14/1774 81/18639 0.172839506172839 1.8159839659276 0.01998359942678 0.149267739620765 GO:0031624 ubiquitin conjugating enzyme binding 7/1774 30/18639 0.233333333333333 2.45157835400226 0.0201352207326012 0.149488759984464 GO:0019205 nucleobase-containing compound kinase activity 9/1774 44/18639 0.204545454545455 2.14911089474224 0.0208999963183507 0.153280561797648 GO:0030551 cyclic nucleotide binding 8/1774 37/18639 0.216216216216216 2.27173283768549 0.0209293800431383 0.153280561797648 GO:0008179 adenylate cyclase binding 4/1774 12/18639 0.333333333333333 3.50225479143179 0.0216933842928933 0.153280561797648 GO:0034452 dynactin binding 4/1774 12/18639 0.333333333333333 3.50225479143179 0.0216933842928933 0.153280561797648 GO:0035251 UDP-glucosyltransferase activity 4/1774 12/18639 0.333333333333333 3.50225479143179 0.0216933842928933 0.153280561797648 GO:0070679 inositol 1,4,5 trisphosphate binding 4/1774 12/18639 0.333333333333333 3.50225479143179 0.0216933842928933 0.153280561797648 GO:0004842 ubiquitin-protein transferase activity 56/1774 449/18639 0.124721603563474 1.3104205010257 0.0218150799167264 0.153280561797648 GO:0015085 calcium ion transmembrane transporter activity 22/1774 147/18639 0.149659863945578 1.57244092676529 0.0219477350084441 0.153280561797648 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 14/1774 82/18639 0.170731707317073 1.79383782000165 0.0220568981284363 0.153280561797648 GO:0033549 MAP kinase phosphatase activity 14/1774 82/18639 0.170731707317073 1.79383782000165 0.0220568981284363 0.153280561797648 GO:0030552 cAMP binding 6/1774 24/18639 0.25 2.62669109357384 0.0221474770923948 0.153280561797648 GO:0050431 transforming growth factor beta binding 6/1774 24/18639 0.25 2.62669109357384 0.0221474770923948 0.153280561797648 GO:0030295 protein kinase activator activity 21/1774 139/18639 0.151079136690647 1.5873528910806 0.0225190048914317 0.154976297707887 GO:0070064 proline-rich region binding 5/1774 18/18639 0.277777777777778 2.91854565952649 0.0231991630059596 0.15876522168883 GO:0019787 ubiquitin-like protein transferase activity 59/1774 479/18639 0.123173277661795 1.29415260560214 0.0238089491882428 0.161052973395026 GO:0003725 double-stranded RNA binding 13/1774 75/18639 0.173333333333333 1.82117249154453 0.0238693214354203 0.161052973395026 GO:0101005 deubiquitinase activity 18/1774 115/18639 0.156521739130435 1.64453703249841 0.0239278703329753 0.161052973395026 GO:0030165 PDZ domain binding 14/1774 83/18639 0.168674698795181 1.77222531614621 0.0242871329473774 0.162218942348179 GO:0000146 microfilament motor activity 8/1774 38/18639 0.210526315789474 2.2119503945885 0.0243659472588285 0.162218942348179 GO:0030145 manganese ion binding 12/1774 68/18639 0.176470588235294 1.85413488958154 0.0257410471959613 0.17044747467596 GO:0005246 calcium channel regulator activity 10/1774 53/18639 0.188679245283019 1.98240837250856 0.0261575555576516 0.171352970899055 GO:0017046 peptide hormone binding 10/1774 53/18639 0.188679245283019 1.98240837250856 0.0261575555576516 0.171352970899055 GO:0004843 cysteine-type deubiquitinase activity 17/1774 108/18639 0.157407407407407 1.65384254039835 0.0263028164637516 0.171388032809019 GO:0017018 myosin phosphatase activity 14/1774 84/18639 0.166666666666667 1.7511273957159 0.0266807360896583 0.172930696877415 GO:0015271 outward rectifier potassium channel activity 6/1774 25/18639 0.24 2.52162344983089 0.0268598426732473 0.173175301445937 GO:0015026 coreceptor activity 11/1774 61/18639 0.180327868852459 1.89466242815163 0.0276284177788623 0.177197967429876 GO:0019887 protein kinase regulator activity 34/1774 255/18639 0.133333333333333 1.40090191657272 0.0278245690332407 0.177526547217291 GO:0019208 phosphatase regulator activity 18/1774 117/18639 0.153846153846154 1.61642528835314 0.027973925565285 0.17755470889883 GO:0050145 nucleoside monophosphate kinase activity 5/1774 19/18639 0.263157894736842 2.76493799323563 0.0290802863275489 0.183625519336327 GO:0004222 metalloendopeptidase activity 17/1774 110/18639 0.154545454545455 1.62377267602747 0.0308285440863682 0.193666494901544 GO:0097110 scaffold protein binding 12/1774 70/18639 0.171428571428571 1.80115960702206 0.0315868669532761 0.196851916344426 GO:0019783 ubiquitin-like protein peptidase activity 19/1774 127/18639 0.149606299212598 1.5718781347371 0.031657002057022 0.196851916344426 GO:0004435 phosphatidylinositol phospholipase C activity 6/1774 26/18639 0.230769230769231 2.4246379325297 0.0321908106660915 0.19716871532981 GO:0043548 phosphatidylinositol 3-kinase binding 6/1774 26/18639 0.230769230769231 2.4246379325297 0.0321908106660915 0.19716871532981 GO:0050681 nuclear androgen receptor binding 6/1774 26/18639 0.230769230769231 2.4246379325297 0.0321908106660915 0.19716871532981 GO:0002020 protease binding 20/1774 136/18639 0.147058823529412 1.54511240798461 0.0329494921709713 0.199817464898217 GO:0019838 growth factor binding 20/1774 136/18639 0.147058823529412 1.54511240798461 0.0329494921709713 0.199817464898217 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 19/1774 128/18639 0.1484375 1.55959783680947 0.0339825864140142 0.20461249323789 GO:0008194 UDP-glycosyltransferase activity 21/1774 145/18639 0.144827586206897 1.52166932317381 0.0340742437718609 0.20461249323789 GO:0032266 phosphatidylinositol-3-phosphate binding 9/1774 48/18639 0.1875 1.97001832018038 0.0351722046441798 0.210175369215221 GO:0019207 kinase regulator activity 37/1774 287/18639 0.128919860627178 1.35453059877676 0.0354500963600859 0.210807611850025 GO:0010851 cyclase regulator activity 5/1774 20/18639 0.25 2.62669109357384 0.0358219740208892 0.210970760459564 GO:0052745 inositol phosphate phosphatase activity 5/1774 20/18639 0.25 2.62669109357384 0.0358219740208892 0.210970760459564 GO:0001727 lipid kinase activity 8/1774 41/18639 0.195121951219512 2.05010036571617 0.0369975191328279 0.216500347555832 GO:0004705 JUN kinase activity 4/1774 14/18639 0.285714285714286 3.00193267837011 0.0376445502280753 0.216500347555832 GO:0032454 histone H3K9 demethylase activity 4/1774 14/18639 0.285714285714286 3.00193267837011 0.0376445502280753 0.216500347555832 GO:0034236 protein kinase A catalytic subunit binding 4/1774 14/18639 0.285714285714286 3.00193267837011 0.0376445502280753 0.216500347555832 GO:0046030 inositol trisphosphate phosphatase activity 4/1774 14/18639 0.285714285714286 3.00193267837011 0.0376445502280753 0.216500347555832 GO:0035255 ionotropic glutamate receptor binding 6/1774 27/18639 0.222222222222222 2.33483652762119 0.0381641167062272 0.218462817594058 GO:0140030 modification-dependent protein binding 24/1774 173/18639 0.138728323699422 1.4575858091508 0.0388028018541477 0.221085731494563 GO:0035254 glutamate receptor binding 9/1774 49/18639 0.183673469387755 1.9298138646665 0.0395835164030205 0.224489849970834 GO:0019209 kinase activator activity 21/1774 148/18639 0.141891891891892 1.4908246747311 0.0412856895758141 0.23306437663766 GO:0016755 aminoacyltransferase activity 59/1774 496/18639 0.118951612903226 1.24979656871659 0.0431727474875841 0.241928702080109 GO:0036122 BMP binding 5/1774 21/18639 0.238095238095238 2.50161056530842 0.0434484199654073 0.241928702080109 GO:0072542 protein phosphatase activator activity 5/1774 21/18639 0.238095238095238 2.50161056530842 0.0434484199654073 0.241928702080109 GO:0005245 voltage-gated calcium channel activity 8/1774 43/18639 0.186046511627907 1.95474686033402 0.0475008945693015 0.26134479069503 GO:0005523 tropomyosin binding 4/1774 15/18639 0.266666666666667 2.80180383314543 0.0475754190408095 0.26134479069503 GO:0031005 filamin binding 4/1774 15/18639 0.266666666666667 2.80180383314543 0.0475754190408095 0.26134479069503 GO:0044390 ubiquitin-like protein conjugating enzyme binding 7/1774 36/18639 0.194444444444444 2.04298196166855 0.0502631217704223 0.27451369642553 GO:0045309 protein phosphorylated amino acid binding 10/1774 59/18639 0.169491525423729 1.78080752106701 0.0504208830169342 0.27451369642553 GO:0016881 acid-amino acid ligase activity 5/1774 22/18639 0.227272727272727 2.38790099415804 0.0519741911738609 0.277532374852514 GO:0003785 actin monomer binding 6/1774 29/18639 0.206896551724138 2.17381331881973 0.0521081193600639 0.277532374852514 GO:0004629 phospholipase C activity 6/1774 29/18639 0.206896551724138 2.17381331881973 0.0521081193600639 0.277532374852514 GO:0043236 laminin binding 6/1774 29/18639 0.206896551724138 2.17381331881973 0.0521081193600639 0.277532374852514 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 6/1774 29/18639 0.206896551724138 2.17381331881973 0.0521081193600639 0.277532374852514 GO:0043178 alcohol binding 14/1774 92/18639 0.152173913043478 1.59885544826234 0.0524208485137728 0.277989348179098 GO:0030020 extracellular matrix structural constituent conferring tensile strength 8/1774 44/18639 0.181818181818182 1.91032079532643 0.053412205291735 0.282025652941273 GO:0030159 signaling receptor complex adaptor activity 9/1774 52/18639 0.173076923076923 1.81847844939728 0.0550145615571061 0.289239647671481 GO:0003777 microtubule motor activity 11/1774 68/18639 0.161764705882353 1.69962364878308 0.0553920108024411 0.289979543730728 GO:0004707 MAP kinase activity 4/1774 16/18639 0.25 2.62669109357384 0.0588092344785394 0.300598612882766 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 4/1774 16/18639 0.25 2.62669109357384 0.0588092344785394 0.300598612882766 GO:0030275 LRR domain binding 4/1774 16/18639 0.25 2.62669109357384 0.0588092344785394 0.300598612882766 GO:0031435 mitogen-activated protein kinase kinase kinase binding 4/1774 16/18639 0.25 2.62669109357384 0.0588092344785394 0.300598612882766 GO:0034450 ubiquitin-ubiquitin ligase activity 4/1774 16/18639 0.25 2.62669109357384 0.0588092344785394 0.300598612882766 GO:0098918 structural constituent of synapse 6/1774 30/18639 0.2 2.10135287485908 0.0601013440169295 0.300598612882766 GO:0002039 p53 binding 11/1774 69/18639 0.159420289855072 1.67499142198912 0.0604816178457501 0.300598612882766 GO:0051018 protein kinase A binding 9/1774 53/18639 0.169811320754717 1.78416753525771 0.0609171309660855 0.300598612882766 GO:0140296 general transcription initiation factor binding 9/1774 53/18639 0.169811320754717 1.78416753525771 0.0609171309660855 0.300598612882766 GO:0005158 insulin receptor binding 5/1774 23/18639 0.217391304347826 2.28407921180334 0.0614044259444727 0.300598612882766 GO:0016849 phosphorus-oxygen lyase activity 5/1774 23/18639 0.217391304347826 2.28407921180334 0.0614044259444727 0.300598612882766 GO:0099186 structural constituent of postsynapse 5/1774 23/18639 0.217391304347826 2.28407921180334 0.0614044259444727 0.300598612882766 GO:0000182 rDNA binding 3/1774 10/18639 0.3 3.15202931228861 0.0620828155586448 0.300598612882766 GO:0004862 cAMP-dependent protein kinase inhibitor activity 3/1774 10/18639 0.3 3.15202931228861 0.0620828155586448 0.300598612882766 GO:0015279 store-operated calcium channel activity 3/1774 10/18639 0.3 3.15202931228861 0.0620828155586448 0.300598612882766 GO:0015643 toxic substance binding 3/1774 10/18639 0.3 3.15202931228861 0.0620828155586448 0.300598612882766 GO:0031996 thioesterase binding 3/1774 10/18639 0.3 3.15202931228861 0.0620828155586448 0.300598612882766 GO:0035374 chondroitin sulfate binding 3/1774 10/18639 0.3 3.15202931228861 0.0620828155586448 0.300598612882766 GO:0051864 histone H3K36 demethylase activity 3/1774 10/18639 0.3 3.15202931228861 0.0620828155586448 0.300598612882766 GO:0004722 protein serine/threonine phosphatase activity 15/1774 103/18639 0.145631067961165 1.53011131664496 0.0631316329394107 0.304473426577866 GO:0019199 transmembrane receptor protein kinase activity 12/1774 78/18639 0.153846153846154 1.61642528835314 0.0644519242364677 0.30962198897911 GO:0030276 clathrin binding 8/1774 46/18639 0.173913043478261 1.82726336944267 0.0665926991148021 0.318656470373565 GO:0005262 calcium channel activity 18/1774 131/18639 0.137404580152672 1.44367754761311 0.0716609127958687 0.340603187592121 GO:0070300 phosphatidic acid binding 5/1774 24/18639 0.208333333333333 2.18890924464487 0.0717352019581773 0.340603187592121 GO:0001784 phosphotyrosine residue binding 8/1774 47/18639 0.170212765957447 1.78838542541198 0.0738710989951647 0.349390333085238 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 33/1774 268/18639 0.123134328358209 1.29374337444682 0.0750335848065373 0.353523620723108 GO:0061630 ubiquitin protein ligase activity 42/1774 353/18639 0.118980169971671 1.25009661110597 0.0771468818202493 0.36146812153142 GO:0016247 channel regulator activity 22/1774 168/18639 0.130952380952381 1.37588581091963 0.0773099166050874 0.36146812153142 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 3/1774 11/18639 0.272727272727273 2.86548119298965 0.0795065511279558 0.362065149188647 GO:0004016 adenylate cyclase activity 3/1774 11/18639 0.272727272727273 2.86548119298965 0.0795065511279558 0.362065149188647 GO:0004143 ATP-dependent diacylglycerol kinase activity 3/1774 11/18639 0.272727272727273 2.86548119298965 0.0795065511279558 0.362065149188647 GO:0019206 nucleoside kinase activity 3/1774 11/18639 0.272727272727273 2.86548119298965 0.0795065511279558 0.362065149188647 GO:0019215 intermediate filament binding 3/1774 11/18639 0.272727272727273 2.86548119298965 0.0795065511279558 0.362065149188647 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 3/1774 11/18639 0.272727272727273 2.86548119298965 0.0795065511279558 0.362065149188647 GO:0043522 leucine zipper domain binding 3/1774 11/18639 0.272727272727273 2.86548119298965 0.0795065511279558 0.362065149188647 GO:0061791 GTPase motor activity 7/1774 40/18639 0.175 1.83868376550169 0.0809445697741541 0.365893350455124 GO:1990606 membrane scission GTPase motor activity 7/1774 40/18639 0.175 1.83868376550169 0.0809445697741541 0.365893350455124 GO:0099106 ion channel regulator activity 21/1774 160/18639 0.13125 1.37901282412627 0.0813108480971929 0.366197753378902 GO:0000030 mannosyltransferase activity 5/1774 25/18639 0.2 2.10135287485908 0.08295404177941 0.369522549744644 GO:0019211 phosphatase activator activity 5/1774 25/18639 0.2 2.10135287485908 0.08295404177941 0.369522549744644 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 5/1774 25/18639 0.2 2.10135287485908 0.08295404177941 0.369522549744644 GO:0019210 kinase inhibitor activity 13/1774 90/18639 0.144444444444444 1.51764374295378 0.0837977036196914 0.371928213529427 GO:0000400 four-way junction DNA binding 4/1774 18/18639 0.222222222222222 2.33483652762119 0.0850705739502058 0.372089583103506 GO:0000900 mRNA regulatory element binding translation repressor activity 4/1774 18/18639 0.222222222222222 2.33483652762119 0.0850705739502058 0.372089583103506 GO:0004706 JUN kinase kinase kinase activity 4/1774 18/18639 0.222222222222222 2.33483652762119 0.0850705739502058 0.372089583103506 GO:0017128 phospholipid scramblase activity 4/1774 18/18639 0.222222222222222 2.33483652762119 0.0850705739502058 0.372089583103506 GO:0141108 transporter regulator activity 22/1774 170/18639 0.129411764705882 1.35969891902646 0.0853527941649674 0.372089583103506 GO:0044325 transmembrane transporter binding 18/1774 136/18639 0.132352941176471 1.39060116718615 0.0947357970209967 0.409016867199163 GO:0050750 low-density lipoprotein particle receptor binding 5/1774 26/18639 0.192307692307692 2.02053161044142 0.0950405253778189 0.409016867199163 GO:0042393 histone binding 30/1774 247/18639 0.121457489878543 1.27612522764721 0.0983785843767545 0.409016867199163 GO:0032813 tumor necrosis factor receptor superfamily binding 8/1774 50/18639 0.16 1.68108229988726 0.0984696842036002 0.409016867199163 GO:0005078 MAP-kinase scaffold activity 3/1774 12/18639 0.25 2.62669109357384 0.0987776067396432 0.409016867199163 GO:0005095 GTPase inhibitor activity 3/1774 12/18639 0.25 2.62669109357384 0.0987776067396432 0.409016867199163 GO:0005527 macrolide binding 3/1774 12/18639 0.25 2.62669109357384 0.0987776067396432 0.409016867199163 GO:0008603 cAMP-dependent protein kinase regulator activity 3/1774 12/18639 0.25 2.62669109357384 0.0987776067396432 0.409016867199163 GO:0015269 calcium-activated potassium channel activity 3/1774 12/18639 0.25 2.62669109357384 0.0987776067396432 0.409016867199163 GO:0045295 gamma-catenin binding 3/1774 12/18639 0.25 2.62669109357384 0.0987776067396432 0.409016867199163 GO:0097677 STAT family protein binding 3/1774 12/18639 0.25 2.62669109357384 0.0987776067396432 0.409016867199163 GO:0052866 phosphatidylinositol phosphate phosphatase activity 6/1774 34/18639 0.176470588235294 1.85413488958154 0.0989098704899212 0.409016867199163 GO:0019894 kinesin binding 7/1774 42/18639 0.166666666666667 1.7511273957159 0.0995844737666989 0.409016867199163 GO:0035198 miRNA binding 7/1774 42/18639 0.166666666666667 1.7511273957159 0.0995844737666989 0.409016867199163 GO:0005229 intracellularly calcium-gated chloride channel activity 4/1774 19/18639 0.210526315789474 2.2119503945885 0.100001317316247 0.409016867199163 GO:0008574 plus-end-directed microtubule motor activity 4/1774 19/18639 0.210526315789474 2.2119503945885 0.100001317316247 0.409016867199163 GO:0046527 glucosyltransferase activity 4/1774 19/18639 0.210526315789474 2.2119503945885 0.100001317316247 0.409016867199163 GO:0141147 intracellularly calcium-gated channel activity 4/1774 19/18639 0.210526315789474 2.2119503945885 0.100001317316247 0.409016867199163 GO:0004860 protein kinase inhibitor activity 12/1774 84/18639 0.142857142857143 1.50096633918505 0.100167396048775 0.409016867199163 GO:0061659 ubiquitin-like protein ligase activity 43/1774 372/18639 0.115591397849462 1.21449158089973 0.104885083124425 0.426857896436613 GO:0005548 phospholipid transporter activity 10/1774 68/18639 0.147058823529412 1.54511240798461 0.10897426273061 0.440776371595697 GO:0001217 DNA-binding transcription repressor activity 33/1774 278/18639 0.118705035971223 1.2472058429919 0.109024686198773 0.440776371595697 GO:0008375 acetylglucosaminyltransferase activity 7/1774 43/18639 0.162790697674419 1.71040350279227 0.109711836388415 0.441475040623388 GO:0043015 gamma-tubulin binding 6/1774 35/18639 0.171428571428571 1.80115960702206 0.110278663208781 0.441475040623388 GO:0140566 histone reader activity 6/1774 35/18639 0.171428571428571 1.80115960702206 0.110278663208781 0.441475040623388 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 4/1774 20/18639 0.2 2.10135287485908 0.116046153140087 0.463050611063865 GO:0002161 aminoacyl-tRNA editing activity 3/1774 13/18639 0.230769230769231 2.4246379325297 0.119704191593282 0.4710697108159 GO:0005172 vascular endothelial growth factor receptor binding 3/1774 13/18639 0.230769230769231 2.4246379325297 0.119704191593282 0.4710697108159 GO:0008253 5'-nucleotidase activity 3/1774 13/18639 0.230769230769231 2.4246379325297 0.119704191593282 0.4710697108159 GO:0043560 insulin receptor substrate binding 3/1774 13/18639 0.230769230769231 2.4246379325297 0.119704191593282 0.4710697108159 GO:0016248 channel inhibitor activity 7/1774 44/18639 0.159090909090909 1.67153069591063 0.120363117947246 0.4710697108159 GO:0043014 alpha-tubulin binding 7/1774 44/18639 0.159090909090909 1.67153069591063 0.120363117947246 0.4710697108159 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 5/1774 28/18639 0.178571428571429 1.87620792398132 0.121699235727045 0.473274805605174 GO:0141052 histone H3 demethylase activity 5/1774 28/18639 0.178571428571429 1.87620792398132 0.121699235727045 0.473274805605174 GO:0045505 dynein intermediate chain binding 6/1774 36/18639 0.166666666666667 1.7511273957159 0.122281771496453 0.474035348364413 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 54/1774 484/18639 0.111570247933884 1.17224230622304 0.122886382494215 0.474876399228433 GO:0000149 SNARE binding 14/1774 106/18639 0.132075471698113 1.38768586075599 0.13041968720726 0.502402883109729 GO:0140303 intramembrane lipid transporter activity 7/1774 45/18639 0.155555555555556 1.63438556933484 0.13152422479143 0.503491173029693 GO:0141110 transporter inhibitor activity 7/1774 45/18639 0.155555555555556 1.63438556933484 0.13152422479143 0.503491173029693 GO:0008373 sialyltransferase activity 4/1774 21/18639 0.19047619047619 2.00128845224674 0.1331279727106 0.506465113572935 GO:0035613 RNA stem-loop binding 4/1774 21/18639 0.19047619047619 2.00128845224674 0.1331279727106 0.506465113572935 GO:0043394 proteoglycan binding 6/1774 37/18639 0.162162162162162 1.70379962826412 0.13489611536542 0.511602914311577 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 5/1774 29/18639 0.172413793103448 1.81151109901644 0.136197384970165 0.513359374118316 GO:0097472 cyclin-dependent protein kinase activity 5/1774 29/18639 0.172413793103448 1.81151109901644 0.136197384970165 0.513359374118316 GO:0003925 G protein activity 8/1774 54/18639 0.148148148148148 1.5565576850808 0.137555212842397 0.516886919423118 GO:0008191 metalloendopeptidase inhibitor activity 3/1774 14/18639 0.214285714285714 2.25144950877758 0.142084093783793 0.525839924124308 GO:0008331 high voltage-gated calcium channel activity 3/1774 14/18639 0.214285714285714 2.25144950877758 0.142084093783793 0.525839924124308 GO:0019992 diacylglycerol binding 3/1774 14/18639 0.214285714285714 2.25144950877758 0.142084093783793 0.525839924124308 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 3/1774 14/18639 0.214285714285714 2.25144950877758 0.142084093783793 0.525839924124308 GO:1990825 sequence-specific mRNA binding 3/1774 14/18639 0.214285714285714 2.25144950877758 0.142084093783793 0.525839924124308 GO:0030291 protein serine/threonine kinase inhibitor activity 7/1774 46/18639 0.152173913043478 1.59885544826234 0.143178601194927 0.528294537541523 GO:0001216 DNA-binding transcription activator activity 54/1774 491/18639 0.109979633401222 1.15553009411803 0.146094357510137 0.537434198047801 GO:0043531 ADP binding 6/1774 38/18639 0.157894736842105 1.65896279594138 0.148095208530028 0.542354756204665 GO:0016779 nucleotidyltransferase activity 17/1774 136/18639 0.125 1.31334554678692 0.148685987018464 0.542354756204665 GO:0008093 cytoskeletal anchor activity 4/1774 22/18639 0.181818181818182 1.91032079532643 0.151162146385431 0.542354756204665 GO:0070034 telomerase RNA binding 4/1774 22/18639 0.181818181818182 1.91032079532643 0.151162146385431 0.542354756204665 GO:0001965 G-protein alpha-subunit binding 5/1774 30/18639 0.166666666666667 1.7511273957159 0.151416593160813 0.542354756204665 GO:0031210 phosphatidylcholine binding 5/1774 30/18639 0.166666666666667 1.7511273957159 0.151416593160813 0.542354756204665 GO:0032452 histone demethylase activity 5/1774 30/18639 0.166666666666667 1.7511273957159 0.151416593160813 0.542354756204665 GO:0035925 mRNA 3'-UTR AU-rich region binding 5/1774 30/18639 0.166666666666667 1.7511273957159 0.151416593160813 0.542354756204665 GO:0070566 adenylyltransferase activity 5/1774 30/18639 0.166666666666667 1.7511273957159 0.151416593160813 0.542354756204665 GO:0008237 metallopeptidase activity 22/1774 184/18639 0.119565217391304 1.25624356649184 0.156745810836117 0.559806467271846 GO:0004857 enzyme inhibitor activity 46/1774 416/18639 0.110576923076923 1.16180567600382 0.158947229864842 0.566018478443114 GO:0016887 ATP hydrolysis activity 46/1774 417/18639 0.11031175059952 1.1590195712652 0.162988956510021 0.573435865890352 GO:0000774 adenyl-nucleotide exchange factor activity 3/1774 15/18639 0.2 2.10135287485908 0.165711262469538 0.573435865890352 GO:0004559 alpha-mannosidase activity 3/1774 15/18639 0.2 2.10135287485908 0.165711262469538 0.573435865890352 GO:0005041 low-density lipoprotein particle receptor activity 3/1774 15/18639 0.2 2.10135287485908 0.165711262469538 0.573435865890352 GO:0008252 nucleotidase activity 3/1774 15/18639 0.2 2.10135287485908 0.165711262469538 0.573435865890352 GO:0015556 C4-dicarboxylate transmembrane transporter activity 3/1774 15/18639 0.2 2.10135287485908 0.165711262469538 0.573435865890352 GO:0030553 cGMP binding 3/1774 15/18639 0.2 2.10135287485908 0.165711262469538 0.573435865890352 GO:0045504 dynein heavy chain binding 3/1774 15/18639 0.2 2.10135287485908 0.165711262469538 0.573435865890352 GO:0120283 protein serine/threonine kinase binding 3/1774 15/18639 0.2 2.10135287485908 0.165711262469538 0.573435865890352 GO:0140776 protein-containing complex destabilizing activity 3/1774 15/18639 0.2 2.10135287485908 0.165711262469538 0.573435865890352 GO:0005164 tumor necrosis factor receptor binding 5/1774 31/18639 0.161290322580645 1.69463941520893 0.167307878142676 0.574095660293496 GO:0017147 Wnt-protein binding 5/1774 31/18639 0.161290322580645 1.69463941520893 0.167307878142676 0.574095660293496 GO:0140457 protein demethylase activity 5/1774 31/18639 0.161290322580645 1.69463941520893 0.167307878142676 0.574095660293496 GO:0043274 phospholipase binding 4/1774 23/18639 0.173913043478261 1.82726336944267 0.170058508583527 0.580283211740448 GO:0070577 lysine-acetylated histone binding 4/1774 23/18639 0.173913043478261 1.82726336944267 0.170058508583527 0.580283211740448 GO:0019001 guanyl nucleotide binding 44/1774 400/18639 0.11 1.15574408117249 0.174002329212951 0.590451117135362 GO:0032561 guanyl ribonucleotide binding 44/1774 400/18639 0.11 1.15574408117249 0.174002329212951 0.590451117135362 GO:0032451 demethylase activity 6/1774 40/18639 0.15 1.57601465614431 0.176126868884917 0.594367532738357 GO:0050997 quaternary ammonium group binding 6/1774 40/18639 0.15 1.57601465614431 0.176126868884917 0.594367532738357 GO:0004713 protein tyrosine kinase activity 17/1774 140/18639 0.121428571428571 1.2758213883073 0.177368985661488 0.596914855591547 GO:0008408 3'-5' exonuclease activity 8/1774 58/18639 0.137931034482759 1.44920887921316 0.18323805913276 0.613564396572057 GO:0071813 lipoprotein particle binding 5/1774 32/18639 0.15625 1.64168193348365 0.183818884524037 0.613564396572057 GO:0071814 protein-lipid complex binding 5/1774 32/18639 0.15625 1.64168193348365 0.183818884524037 0.613564396572057 GO:0005315 phosphate transmembrane transporter activity 4/1774 24/18639 0.166666666666667 1.7511273957159 0.189723169908597 0.620257121050393 GO:0035035 histone acetyltransferase binding 4/1774 24/18639 0.166666666666667 1.7511273957159 0.189723169908597 0.620257121050393 GO:0050699 WW domain binding 4/1774 24/18639 0.166666666666667 1.7511273957159 0.189723169908597 0.620257121050393 GO:0140033 acetylation-dependent protein binding 4/1774 24/18639 0.166666666666667 1.7511273957159 0.189723169908597 0.620257121050393 GO:0005159 insulin-like growth factor receptor binding 3/1774 16/18639 0.1875 1.97001832018038 0.190380961236692 0.620257121050393 GO:0008142 oxysterol binding 3/1774 16/18639 0.1875 1.97001832018038 0.190380961236692 0.620257121050393 GO:0015923 mannosidase activity 3/1774 16/18639 0.1875 1.97001832018038 0.190380961236692 0.620257121050393 GO:0070411 I-SMAD binding 3/1774 16/18639 0.1875 1.97001832018038 0.190380961236692 0.620257121050393 GO:0140327 flippase activity 3/1774 16/18639 0.1875 1.97001832018038 0.190380961236692 0.620257121050393 GO:0015459 potassium channel regulator activity 8/1774 59/18639 0.135593220338983 1.42464601685361 0.195576868056555 0.635495128300476 GO:0043175 RNA polymerase core enzyme binding 6/1774 42/18639 0.142857142857143 1.50096633918505 0.206110810121934 0.666641657257795 GO:0005048 signal sequence binding 7/1774 51/18639 0.137254901960784 1.44210491411897 0.208121886948247 0.666641657257795 GO:0001098 basal transcription machinery binding 8/1774 60/18639 0.133333333333333 1.40090191657272 0.208246011119232 0.666641657257795 GO:0001099 basal RNA polymerase II transcription machinery binding 8/1774 60/18639 0.133333333333333 1.40090191657272 0.208246011119232 0.666641657257795 GO:0005525 GTP binding 41/1774 378/18639 0.108465608465608 1.13962259086273 0.20914533941598 0.666641657257795 GO:0003707 nuclear steroid receptor activity 4/1774 25/18639 0.16 1.68108229988726 0.210060146695109 0.666641657257795 GO:0008139 nuclear localization sequence binding 4/1774 25/18639 0.16 1.68108229988726 0.210060146695109 0.666641657257795 GO:0017025 TBP-class protein binding 4/1774 25/18639 0.16 1.68108229988726 0.210060146695109 0.666641657257795 GO:0017056 structural constituent of nuclear pore 4/1774 25/18639 0.16 1.68108229988726 0.210060146695109 0.666641657257795 GO:0004550 nucleoside diphosphate kinase activity 3/1774 17/18639 0.176470588235294 1.85413488958154 0.215893730462094 0.669543847635607 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 3/1774 17/18639 0.176470588235294 1.85413488958154 0.215893730462094 0.669543847635607 GO:0015278 intracellularly gated calcium channel activity 3/1774 17/18639 0.176470588235294 1.85413488958154 0.215893730462094 0.669543847635607 GO:0019198 transmembrane receptor protein phosphatase activity 3/1774 17/18639 0.176470588235294 1.85413488958154 0.215893730462094 0.669543847635607 GO:0030169 low-density lipoprotein particle binding 3/1774 17/18639 0.176470588235294 1.85413488958154 0.215893730462094 0.669543847635607 GO:0032183 SUMO binding 3/1774 17/18639 0.176470588235294 1.85413488958154 0.215893730462094 0.669543847635607 GO:0038191 neuropilin binding 3/1774 17/18639 0.176470588235294 1.85413488958154 0.215893730462094 0.669543847635607 GO:0048038 quinone binding 3/1774 17/18639 0.176470588235294 1.85413488958154 0.215893730462094 0.669543847635607 GO:1990226 histone methyltransferase binding 3/1774 17/18639 0.176470588235294 1.85413488958154 0.215893730462094 0.669543847635607 GO:1990782 protein tyrosine kinase binding 14/1774 117/18639 0.11965811965812 1.25721966871911 0.221728179784314 0.682776138421553 GO:0008200 ion channel inhibitor activity 6/1774 43/18639 0.13953488372093 1.46606014525052 0.221743076132774 0.682776138421553 GO:0003924 GTPase activity 36/1774 331/18639 0.108761329305136 1.14272966004421 0.221832573952472 0.682776138421553 GO:0005160 transforming growth factor beta receptor binding 4/1774 26/18639 0.153846153846154 1.61642528835314 0.230972805116435 0.692261030372618 GO:0030507 spectrin binding 4/1774 26/18639 0.153846153846154 1.61642528835314 0.230972805116435 0.692261030372618 GO:0052742 phosphatidylinositol kinase activity 4/1774 26/18639 0.153846153846154 1.61642528835314 0.230972805116435 0.692261030372618 GO:0070006 metalloaminopeptidase activity 4/1774 26/18639 0.153846153846154 1.61642528835314 0.230972805116435 0.692261030372618 GO:0070412 R-SMAD binding 4/1774 26/18639 0.153846153846154 1.61642528835314 0.230972805116435 0.692261030372618 GO:0097602 cullin family protein binding 4/1774 26/18639 0.153846153846154 1.61642528835314 0.230972805116435 0.692261030372618 GO:0001223 transcription coactivator binding 6/1774 44/18639 0.136363636363636 1.43274059649482 0.237750437951542 0.692261030372618 GO:0008525 phosphatidylcholine transporter activity 3/1774 18/18639 0.166666666666667 1.7511273957159 0.242058361764471 0.692261030372618 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 3/1774 18/18639 0.166666666666667 1.7511273957159 0.242058361764471 0.692261030372618 GO:0030228 lipoprotein particle receptor activity 3/1774 18/18639 0.166666666666667 1.7511273957159 0.242058361764471 0.692261030372618 GO:0031690 adrenergic receptor binding 3/1774 18/18639 0.166666666666667 1.7511273957159 0.242058361764471 0.692261030372618 GO:0050811 GABA receptor binding 3/1774 18/18639 0.166666666666667 1.7511273957159 0.242058361764471 0.692261030372618 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 3/1774 18/18639 0.166666666666667 1.7511273957159 0.242058361764471 0.692261030372618 GO:0008234 cysteine-type peptidase activity 21/1774 187/18639 0.112299465240642 1.1799040206428 0.243599071015839 0.692261030372618 GO:0004382 GDP phosphatase activity 2/1774 10/18639 0.2 2.10135287485908 0.245258193617727 0.692261030372618 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 2/1774 10/18639 0.2 2.10135287485908 0.245258193617727 0.692261030372618 GO:0004445 inositol-polyphosphate 5-phosphatase activity 2/1774 10/18639 0.2 2.10135287485908 0.245258193617727 0.692261030372618 GO:0004955 prostaglandin receptor activity 2/1774 10/18639 0.2 2.10135287485908 0.245258193617727 0.692261030372618 GO:0005522 profilin binding 2/1774 10/18639 0.2 2.10135287485908 0.245258193617727 0.692261030372618 GO:0005528 FK506 binding 2/1774 10/18639 0.2 2.10135287485908 0.245258193617727 0.692261030372618 GO:0008641 ubiquitin-like modifier activating enzyme activity 2/1774 10/18639 0.2 2.10135287485908 0.245258193617727 0.692261030372618 GO:0015924 mannosyl-oligosaccharide mannosidase activity 2/1774 10/18639 0.2 2.10135287485908 0.245258193617727 0.692261030372618 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/1774 10/18639 0.2 2.10135287485908 0.245258193617727 0.692261030372618 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 2/1774 10/18639 0.2 2.10135287485908 0.245258193617727 0.692261030372618 GO:0031434 mitogen-activated protein kinase kinase binding 2/1774 10/18639 0.2 2.10135287485908 0.245258193617727 0.692261030372618 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 2/1774 10/18639 0.2 2.10135287485908 0.245258193617727 0.692261030372618 GO:0035256 G protein-coupled glutamate receptor binding 2/1774 10/18639 0.2 2.10135287485908 0.245258193617727 0.692261030372618 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 2/1774 10/18639 0.2 2.10135287485908 0.245258193617727 0.692261030372618 GO:0070513 death domain binding 2/1774 10/18639 0.2 2.10135287485908 0.245258193617727 0.692261030372618 GO:0070739 protein-glutamic acid ligase activity 2/1774 10/18639 0.2 2.10135287485908 0.245258193617727 0.692261030372618 GO:0070740 tubulin-glutamic acid ligase activity 2/1774 10/18639 0.2 2.10135287485908 0.245258193617727 0.692261030372618 GO:0099122 RNA polymerase II C-terminal domain binding 2/1774 10/18639 0.2 2.10135287485908 0.245258193617727 0.692261030372618 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 2/1774 10/18639 0.2 2.10135287485908 0.245258193617727 0.692261030372618 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 2/1774 10/18639 0.2 2.10135287485908 0.245258193617727 0.692261030372618 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 2/1774 10/18639 0.2 2.10135287485908 0.245258193617727 0.692261030372618 GO:1990763 arrestin family protein binding 2/1774 10/18639 0.2 2.10135287485908 0.245258193617727 0.692261030372618 GO:0140101 catalytic activity, acting on a tRNA 16/1774 139/18639 0.115107913669065 1.2094117265376 0.248045355776748 0.698518530635671 GO:0032182 ubiquitin-like protein binding 14/1774 120/18639 0.116666666666667 1.22578917700113 0.250485413596635 0.703772090953849 GO:0033218 amide binding 27/1774 247/18639 0.109311740890688 1.14851270488249 0.251618112105176 0.705336813109476 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 4/1774 27/18639 0.148148148148148 1.5565576850808 0.252365122198582 0.705815695646718 GO:0051539 4 iron, 4 sulfur cluster binding 6/1774 45/18639 0.133333333333333 1.40090191657272 0.254092932283867 0.706552310717302 GO:0000993 RNA polymerase II complex binding 5/1774 36/18639 0.138888888888889 1.45927282976325 0.254935609254733 0.706552310717302 GO:0005484 SNAP receptor activity 5/1774 36/18639 0.138888888888889 1.45927282976325 0.254935609254733 0.706552310717302 GO:0016409 palmitoyltransferase activity 5/1774 36/18639 0.138888888888889 1.45927282976325 0.254935609254733 0.706552310717302 GO:1902936 phosphatidylinositol bisphosphate binding 13/1774 111/18639 0.117117117117117 1.23052195374631 0.256508898926523 0.709307903352124 GO:0031072 heat shock protein binding 15/1774 131/18639 0.114503816793893 1.20306462301092 0.263636603396456 0.727375763875358 GO:0098632 cell-cell adhesion mediator activity 7/1774 55/18639 0.127272727272727 1.3372245567285 0.266567611833405 0.732124083977256 GO:0016829 lyase activity 22/1774 200/18639 0.11 1.15574408117249 0.268414147283371 0.732124083977256 GO:0043395 heparan sulfate proteoglycan binding 3/1774 19/18639 0.157894736842105 1.65896279594138 0.268694057598513 0.732124083977256 GO:0046875 ephrin receptor binding 4/1774 28/18639 0.142857142857143 1.50096633918505 0.274142769943838 0.732124083977256 GO:0051959 dynein light intermediate chain binding 4/1774 28/18639 0.142857142857143 1.50096633918505 0.274142769943838 0.732124083977256 GO:0004527 exonuclease activity 10/1774 84/18639 0.119047619047619 1.25080528265421 0.275923022764107 0.732124083977256 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 2/1774 11/18639 0.181818181818182 1.91032079532643 0.282091891948788 0.732124083977256 GO:0000099 sulfur amino acid transmembrane transporter activity 2/1774 11/18639 0.181818181818182 1.91032079532643 0.282091891948788 0.732124083977256 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 2/1774 11/18639 0.181818181818182 1.91032079532643 0.282091891948788 0.732124083977256 GO:0004954 prostanoid receptor activity 2/1774 11/18639 0.181818181818182 1.91032079532643 0.282091891948788 0.732124083977256 GO:0005114 type II transforming growth factor beta receptor binding 2/1774 11/18639 0.181818181818182 1.91032079532643 0.282091891948788 0.732124083977256 GO:0005536 D-glucose binding 2/1774 11/18639 0.181818181818182 1.91032079532643 0.282091891948788 0.732124083977256 GO:0008172 S-methyltransferase activity 2/1774 11/18639 0.181818181818182 1.91032079532643 0.282091891948788 0.732124083977256 GO:0008432 JUN kinase binding 2/1774 11/18639 0.181818181818182 1.91032079532643 0.282091891948788 0.732124083977256 GO:0008526 phosphatidylinositol transfer activity 2/1774 11/18639 0.181818181818182 1.91032079532643 0.282091891948788 0.732124083977256 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 2/1774 11/18639 0.181818181818182 1.91032079532643 0.282091891948788 0.732124083977256 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/1774 11/18639 0.181818181818182 1.91032079532643 0.282091891948788 0.732124083977256 GO:0019107 myristoyltransferase activity 2/1774 11/18639 0.181818181818182 1.91032079532643 0.282091891948788 0.732124083977256 GO:0019203 carbohydrate phosphatase activity 2/1774 11/18639 0.181818181818182 1.91032079532643 0.282091891948788 0.732124083977256 GO:0032050 clathrin heavy chain binding 2/1774 11/18639 0.181818181818182 1.91032079532643 0.282091891948788 0.732124083977256 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 2/1774 11/18639 0.181818181818182 1.91032079532643 0.282091891948788 0.732124083977256 GO:0034713 type I transforming growth factor beta receptor binding 2/1774 11/18639 0.181818181818182 1.91032079532643 0.282091891948788 0.732124083977256 GO:0035252 UDP-xylosyltransferase activity 2/1774 11/18639 0.181818181818182 1.91032079532643 0.282091891948788 0.732124083977256 GO:0042285 xylosyltransferase activity 2/1774 11/18639 0.181818181818182 1.91032079532643 0.282091891948788 0.732124083977256 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 2/1774 11/18639 0.181818181818182 1.91032079532643 0.282091891948788 0.732124083977256 GO:0048185 activin binding 2/1774 11/18639 0.181818181818182 1.91032079532643 0.282091891948788 0.732124083977256 GO:0070697 activin receptor binding 2/1774 11/18639 0.181818181818182 1.91032079532643 0.282091891948788 0.732124083977256 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 2/1774 11/18639 0.181818181818182 1.91032079532643 0.282091891948788 0.732124083977256 GO:0022843 voltage-gated monoatomic cation channel activity 16/1774 143/18639 0.111888111888112 1.17558202789319 0.28524013517516 0.738729736975837 GO:0140938 histone H3 methyltransferase activity 6/1774 47/18639 0.127659574468085 1.34128906905898 0.287621204074133 0.743324841752771 GO:0042162 telomeric DNA binding 5/1774 38/18639 0.131578947368421 1.38246899661781 0.2927215637575 0.754082710789976 GO:0051087 protein-folding chaperone binding 15/1774 134/18639 0.111940298507463 1.1761303404062 0.293014996192676 0.754082710789976 GO:0000339 RNA cap binding 3/1774 20/18639 0.15 1.57601465614431 0.295631923091177 0.759016318817458 GO:0017022 myosin binding 9/1774 76/18639 0.118421052631579 1.24422209695603 0.296171265628363 0.759016318817458 GO:0035401 histone H3Y41 kinase activity 13/1774 115/18639 0.11304347826087 1.18772119013774 0.298955030137623 0.762958149830392 GO:0140801 histone H2AXY142 kinase activity 13/1774 115/18639 0.11304347826087 1.18772119013774 0.298955030137623 0.762958149830392 GO:0042054 histone methyltransferase activity 8/1774 67/18639 0.119402985074627 1.25453902976661 0.304377543209216 0.775181892788544 GO:0016741 transferase activity, transferring one-carbon groups 23/1774 215/18639 0.106976744186047 1.12397944469206 0.308604616056281 0.78431671093142 GO:0061980 regulatory RNA binding 7/1774 58/18639 0.120689655172414 1.26805776931151 0.312987582965828 0.784444444273548 GO:0003720 telomerase activity 2/1774 12/18639 0.166666666666667 1.7511273957159 0.318754748990616 0.784444444273548 GO:0004300 enoyl-CoA hydratase activity 2/1774 12/18639 0.166666666666667 1.7511273957159 0.318754748990616 0.784444444273548 GO:0005436 sodium:phosphate symporter activity 2/1774 12/18639 0.166666666666667 1.7511273957159 0.318754748990616 0.784444444273548 GO:0015132 prostaglandin transmembrane transporter activity 2/1774 12/18639 0.166666666666667 1.7511273957159 0.318754748990616 0.784444444273548 GO:0015368 calcium:monoatomic cation antiporter activity 2/1774 12/18639 0.166666666666667 1.7511273957159 0.318754748990616 0.784444444273548 GO:0016423 tRNA (guanine) methyltransferase activity 2/1774 12/18639 0.166666666666667 1.7511273957159 0.318754748990616 0.784444444273548 GO:0016840 carbon-nitrogen lyase activity 2/1774 12/18639 0.166666666666667 1.7511273957159 0.318754748990616 0.784444444273548 GO:0035014 phosphatidylinositol 3-kinase regulator activity 2/1774 12/18639 0.166666666666667 1.7511273957159 0.318754748990616 0.784444444273548 GO:0035259 nuclear glucocorticoid receptor binding 2/1774 12/18639 0.166666666666667 1.7511273957159 0.318754748990616 0.784444444273548 GO:0035497 cAMP response element binding 2/1774 12/18639 0.166666666666667 1.7511273957159 0.318754748990616 0.784444444273548 GO:0070410 co-SMAD binding 2/1774 12/18639 0.166666666666667 1.7511273957159 0.318754748990616 0.784444444273548 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 2/1774 12/18639 0.166666666666667 1.7511273957159 0.318754748990616 0.784444444273548 GO:0141221 histone deacetylase activity, hydrolytic mechanism 2/1774 12/18639 0.166666666666667 1.7511273957159 0.318754748990616 0.784444444273548 GO:1990459 transferrin receptor binding 2/1774 12/18639 0.166666666666667 1.7511273957159 0.318754748990616 0.784444444273548 GO:1990841 promoter-specific chromatin binding 8/1774 68/18639 0.117647058823529 1.23608992638769 0.318900680202634 0.784444444273548 GO:0016763 pentosyltransferase activity 6/1774 49/18639 0.122448979591837 1.28654257644433 0.322003308682649 0.789075839632852 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 3/1774 21/18639 0.142857142857143 1.50096633918505 0.322715914821273 0.789075839632852 GO:0005123 death receptor binding 3/1774 21/18639 0.142857142857143 1.50096633918505 0.322715914821273 0.789075839632852 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 18/1774 167/18639 0.107784431137725 1.13246562118154 0.324983766690125 0.78912623465963 GO:0046873 metal ion transmembrane transporter activity 46/1774 450/18639 0.102222222222222 1.07402480270575 0.325965518058686 0.78912623465963 GO:0031593 polyubiquitin modification-dependent protein binding 7/1774 59/18639 0.11864406779661 1.24656526474691 0.328792871511308 0.78912623465963 GO:0070063 RNA polymerase binding 7/1774 59/18639 0.11864406779661 1.24656526474691 0.328792871511308 0.78912623465963 GO:0008170 N-methyltransferase activity 11/1774 98/18639 0.112244897959184 1.17933069507397 0.328873935252855 0.78912623465963 GO:0004177 aminopeptidase activity 5/1774 40/18639 0.125 1.31334554678692 0.331373249535801 0.78912623465963 GO:0016279 protein-lysine N-methyltransferase activity 8/1774 69/18639 0.115942028985507 1.21817557962845 0.333550852706617 0.78912623465963 GO:0015370 solute:sodium symporter activity 9/1774 79/18639 0.113924050632911 1.1969731565653 0.336949562235665 0.78912623465963 GO:0005452 solute:inorganic anion antiporter activity 4/1774 31/18639 0.129032258064516 1.35571153216715 0.340887994947397 0.78912623465963 GO:0070273 phosphatidylinositol-4-phosphate binding 4/1774 31/18639 0.129032258064516 1.35571153216715 0.340887994947397 0.78912623465963 GO:0072349 modified amino acid transmembrane transporter activity 4/1774 31/18639 0.129032258064516 1.35571153216715 0.340887994947397 0.78912623465963 GO:0140767 enzyme-substrate adaptor activity 15/1774 139/18639 0.107913669064748 1.133823493629 0.343958565051249 0.78912623465963 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 7/1774 60/18639 0.116666666666667 1.22578917700113 0.344714154959318 0.78912623465963 GO:0016278 lysine N-methyltransferase activity 8/1774 70/18639 0.114285714285714 1.20077307134804 0.348304551365768 0.78912623465963 GO:0015377 chloride:monoatomic cation symporter activity 3/1774 22/18639 0.136363636363636 1.43274059649482 0.349803351942721 0.78912623465963 GO:0032931 histone H3K56 acetyltransferase activity 3/1774 22/18639 0.136363636363636 1.43274059649482 0.349803351942721 0.78912623465963 GO:0043992 histone H3K9 acetyltransferase activity 3/1774 22/18639 0.136363636363636 1.43274059649482 0.349803351942721 0.78912623465963 GO:0043993 histone H3K18 acetyltransferase activity 3/1774 22/18639 0.136363636363636 1.43274059649482 0.349803351942721 0.78912623465963 GO:0043994 histone H3K23 acetyltransferase activity 3/1774 22/18639 0.136363636363636 1.43274059649482 0.349803351942721 0.78912623465963 GO:0043999 histone H2AK5 acetyltransferase activity 3/1774 22/18639 0.136363636363636 1.43274059649482 0.349803351942721 0.78912623465963 GO:0044012 histone H2AK9 acetyltransferase activity 3/1774 22/18639 0.136363636363636 1.43274059649482 0.349803351942721 0.78912623465963 GO:0044014 histone H2BK5 acetyltransferase activity 3/1774 22/18639 0.136363636363636 1.43274059649482 0.349803351942721 0.78912623465963 GO:0044015 histone H2BK12 acetyltransferase activity 3/1774 22/18639 0.136363636363636 1.43274059649482 0.349803351942721 0.78912623465963 GO:0044016 histone H3K4 acetyltransferase activity 3/1774 22/18639 0.136363636363636 1.43274059649482 0.349803351942721 0.78912623465963 GO:0044017 histone H3K27 acetyltransferase activity 3/1774 22/18639 0.136363636363636 1.43274059649482 0.349803351942721 0.78912623465963 GO:0044018 histone H3K36 acetyltransferase activity 3/1774 22/18639 0.136363636363636 1.43274059649482 0.349803351942721 0.78912623465963 GO:0046972 histone H4K16 acetyltransferase activity 3/1774 22/18639 0.136363636363636 1.43274059649482 0.349803351942721 0.78912623465963 GO:0140035 ubiquitin-like protein reader activity 3/1774 22/18639 0.136363636363636 1.43274059649482 0.349803351942721 0.78912623465963 GO:0140908 histone H3K122 acetyltransferase activity 3/1774 22/18639 0.136363636363636 1.43274059649482 0.349803351942721 0.78912623465963 GO:0004812 aminoacyl-tRNA ligase activity 5/1774 41/18639 0.121951219512195 1.28131272857261 0.350884428350331 0.78912623465963 GO:0016875 ligase activity, forming carbon-oxygen bonds 5/1774 41/18639 0.121951219512195 1.28131272857261 0.350884428350331 0.78912623465963 GO:0042169 SH2 domain binding 5/1774 41/18639 0.121951219512195 1.28131272857261 0.350884428350331 0.78912623465963 GO:0043130 ubiquitin binding 11/1774 100/18639 0.11 1.15574408117249 0.353488994702779 0.78912623465963 GO:0003964 RNA-directed DNA polymerase activity 2/1774 13/18639 0.153846153846154 1.61642528835314 0.354945759426495 0.78912623465963 GO:0004535 poly(A)-specific ribonuclease activity 2/1774 13/18639 0.153846153846154 1.61642528835314 0.354945759426495 0.78912623465963 GO:0005338 nucleotide-sugar transmembrane transporter activity 2/1774 13/18639 0.153846153846154 1.61642528835314 0.354945759426495 0.78912623465963 GO:0008035 high-density lipoprotein particle binding 2/1774 13/18639 0.153846153846154 1.61642528835314 0.354945759426495 0.78912623465963 GO:0015651 quaternary ammonium group transmembrane transporter activity 2/1774 13/18639 0.153846153846154 1.61642528835314 0.354945759426495 0.78912623465963 GO:0019855 calcium channel inhibitor activity 2/1774 13/18639 0.153846153846154 1.61642528835314 0.354945759426495 0.78912623465963 GO:0035673 oligopeptide transmembrane transporter activity 2/1774 13/18639 0.153846153846154 1.61642528835314 0.354945759426495 0.78912623465963 GO:0045159 myosin II binding 2/1774 13/18639 0.153846153846154 1.61642528835314 0.354945759426495 0.78912623465963 GO:0046974 histone H3K9 methyltransferase activity 2/1774 13/18639 0.153846153846154 1.61642528835314 0.354945759426495 0.78912623465963 GO:0046975 histone H3K36 methyltransferase activity 2/1774 13/18639 0.153846153846154 1.61642528835314 0.354945759426495 0.78912623465963 GO:0071714 icosanoid transmembrane transporter activity 2/1774 13/18639 0.153846153846154 1.61642528835314 0.354945759426495 0.78912623465963 GO:0071837 HMG box domain binding 2/1774 13/18639 0.153846153846154 1.61642528835314 0.354945759426495 0.78912623465963 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 2/1774 13/18639 0.153846153846154 1.61642528835314 0.354945759426495 0.78912623465963 GO:0097157 pre-mRNA intronic binding 2/1774 13/18639 0.153846153846154 1.61642528835314 0.354945759426495 0.78912623465963 GO:0140333 glycerophospholipid flippase activity 2/1774 13/18639 0.153846153846154 1.61642528835314 0.354945759426495 0.78912623465963 GO:0140410 monoatomic cation:bicarbonate symporter activity 2/1774 13/18639 0.153846153846154 1.61642528835314 0.354945759426495 0.78912623465963 GO:1901338 catecholamine binding 2/1774 13/18639 0.153846153846154 1.61642528835314 0.354945759426495 0.78912623465963 GO:0005010 insulin-like growth factor receptor activity 6/1774 51/18639 0.117647058823529 1.23608992638769 0.356920038576197 0.790645655073853 GO:0016830 carbon-carbon lyase activity 6/1774 51/18639 0.117647058823529 1.23608992638769 0.356920038576197 0.790645655073853 GO:0016836 hydro-lyase activity 7/1774 61/18639 0.114754098360656 1.20569427246013 0.360721990408418 0.796188177027589 GO:0019905 syntaxin binding 7/1774 61/18639 0.114754098360656 1.20569427246013 0.360721990408418 0.796188177027589 GO:0070717 poly-purine tract binding 4/1774 32/18639 0.125 1.31334554678692 0.363326439293591 0.800494403119871 GO:0004520 DNA endonuclease activity 5/1774 42/18639 0.119047619047619 1.25080528265421 0.370448430813629 0.813260443990493 GO:0048487 beta-tubulin binding 5/1774 42/18639 0.119047619047619 1.25080528265421 0.370448430813629 0.813260443990493 GO:0017134 fibroblast growth factor binding 3/1774 23/18639 0.130434782608696 1.37044752708201 0.3767650784466 0.818328406200505 GO:0031681 G-protein beta-subunit binding 3/1774 23/18639 0.130434782608696 1.37044752708201 0.3767650784466 0.818328406200505 GO:0042171 lysophosphatidic acid acyltransferase activity 3/1774 23/18639 0.130434782608696 1.37044752708201 0.3767650784466 0.818328406200505 GO:0044013 histone H2B acetyltransferase activity 3/1774 23/18639 0.130434782608696 1.37044752708201 0.3767650784466 0.818328406200505 GO:0071617 lysophospholipid acyltransferase activity 3/1774 23/18639 0.130434782608696 1.37044752708201 0.3767650784466 0.818328406200505 GO:0140103 catalytic activity, acting on a glycoprotein 3/1774 23/18639 0.130434782608696 1.37044752708201 0.3767650784466 0.818328406200505 GO:0052689 carboxylic ester hydrolase activity 10/1774 92/18639 0.108695652173913 1.14203960590167 0.37864399100182 0.820953785800407 GO:0140311 protein sequestering activity 4/1774 33/18639 0.121212121212121 1.27354719688429 0.385730826961228 0.827452961994536 GO:0008168 methyltransferase activity 21/1774 204/18639 0.102941176470588 1.08157868558923 0.386123369235123 0.827452961994536 GO:0004065 arylsulfatase activity 2/1774 14/18639 0.142857142857143 1.50096633918505 0.390422703700279 0.827452961994536 GO:0005313 L-glutamate transmembrane transporter activity 2/1774 14/18639 0.142857142857143 1.50096633918505 0.390422703700279 0.827452961994536 GO:0005347 ATP transmembrane transporter activity 2/1774 14/18639 0.142857142857143 1.50096633918505 0.390422703700279 0.827452961994536 GO:0008174 mRNA methyltransferase activity 2/1774 14/18639 0.142857142857143 1.50096633918505 0.390422703700279 0.827452961994536 GO:0008195 phosphatidate phosphatase activity 2/1774 14/18639 0.142857142857143 1.50096633918505 0.390422703700279 0.827452961994536 GO:0030983 mismatched DNA binding 2/1774 14/18639 0.142857142857143 1.50096633918505 0.390422703700279 0.827452961994536 GO:0042043 neurexin family protein binding 2/1774 14/18639 0.142857142857143 1.50096633918505 0.390422703700279 0.827452961994536 GO:0042813 Wnt receptor activity 2/1774 14/18639 0.142857142857143 1.50096633918505 0.390422703700279 0.827452961994536 GO:0070742 C2H2 zinc finger domain binding 2/1774 14/18639 0.142857142857143 1.50096633918505 0.390422703700279 0.827452961994536 GO:0071933 Arp2/3 complex binding 2/1774 14/18639 0.142857142857143 1.50096633918505 0.390422703700279 0.827452961994536 GO:0098847 sequence-specific single stranded DNA binding 2/1774 14/18639 0.142857142857143 1.50096633918505 0.390422703700279 0.827452961994536 GO:0001540 amyloid-beta binding 9/1774 83/18639 0.108433734939759 1.13928770323685 0.392551491647493 0.830527767302555 GO:0001664 G protein-coupled receptor binding 30/1774 297/18639 0.101010101010101 1.06128933073691 0.393564633240083 0.831235647791554 GO:0019955 cytokine binding 15/1774 144/18639 0.104166666666667 1.09445462232244 0.396523077645122 0.836042633589113 GO:0001091 RNA polymerase II general transcription initiation factor binding 3/1774 24/18639 0.125 1.31334554678692 0.403485351094886 0.841945382155463 GO:0005540 hyaluronic acid binding 3/1774 24/18639 0.125 1.31334554678692 0.403485351094886 0.841945382155463 GO:0043998 histone H2A acetyltransferase activity 3/1774 24/18639 0.125 1.31334554678692 0.403485351094886 0.841945382155463 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 3/1774 24/18639 0.125 1.31334554678692 0.403485351094886 0.841945382155463 GO:0070840 dynein complex binding 3/1774 24/18639 0.125 1.31334554678692 0.403485351094886 0.841945382155463 GO:0180051 translation factor activity 9/1774 84/18639 0.107142857142857 1.12572475438879 0.4065469079135 0.841945382155463 GO:0035064 methylated histone binding 8/1774 74/18639 0.108108108108108 1.13586641884274 0.40789445984467 0.841945382155463 GO:0008175 tRNA methyltransferase activity 4/1774 34/18639 0.117647058823529 1.23608992638769 0.408031176195323 0.841945382155463 GO:0016831 carboxy-lyase activity 4/1774 34/18639 0.117647058823529 1.23608992638769 0.408031176195323 0.841945382155463 GO:0030332 cyclin binding 4/1774 34/18639 0.117647058823529 1.23608992638769 0.408031176195323 0.841945382155463 GO:0090482 vitamin transmembrane transporter activity 4/1774 34/18639 0.117647058823529 1.23608992638769 0.408031176195323 0.841945382155463 GO:0004536 DNA nuclease activity 7/1774 64/18639 0.109375 1.14917735343856 0.408979483962514 0.841945382155463 GO:0001046 core promoter sequence-specific DNA binding 5/1774 44/18639 0.113636363636364 1.19395049707902 0.409536012914562 0.841945382155463 GO:0015485 cholesterol binding 6/1774 54/18639 0.111111111111111 1.1674182638106 0.409632202256862 0.841945382155463 GO:0050661 NADP binding 6/1774 54/18639 0.111111111111111 1.1674182638106 0.409632202256862 0.841945382155463 GO:0015293 symporter activity 15/1774 146/18639 0.102739726027397 1.07946209324952 0.417778674896857 0.849918340285037 GO:0008276 protein methyltransferase activity 10/1774 95/18639 0.105263157894737 1.10597519729425 0.418252052734557 0.849918340285037 GO:0019003 GDP binding 8/1774 75/18639 0.106666666666667 1.12072153325817 0.42282442266377 0.849918340285037 GO:0004953 icosanoid receptor activity 2/1774 15/18639 0.133333333333333 1.40090191657272 0.424993694658855 0.849918340285037 GO:0005402 carbohydrate:monoatomic cation symporter activity 2/1774 15/18639 0.133333333333333 1.40090191657272 0.424993694658855 0.849918340285037 GO:0017081 chloride channel regulator activity 2/1774 15/18639 0.133333333333333 1.40090191657272 0.424993694658855 0.849918340285037 GO:0047372 monoacylglycerol lipase activity 2/1774 15/18639 0.133333333333333 1.40090191657272 0.424993694658855 0.849918340285037 GO:0050780 dopamine receptor binding 2/1774 15/18639 0.133333333333333 1.40090191657272 0.424993694658855 0.849918340285037 GO:0061578 K63-linked deubiquitinase activity 2/1774 15/18639 0.133333333333333 1.40090191657272 0.424993694658855 0.849918340285037 GO:0141050 histone H3K deacetylase activity 2/1774 15/18639 0.133333333333333 1.40090191657272 0.424993694658855 0.849918340285037 GO:0141051 histone H4K deacetylase activity 2/1774 15/18639 0.133333333333333 1.40090191657272 0.424993694658855 0.849918340285037 GO:0038024 cargo receptor activity 7/1774 65/18639 0.107692307692308 1.13149770184719 0.425052031068763 0.849918340285037 GO:0160215 deacylase activity 7/1774 65/18639 0.107692307692308 1.13149770184719 0.425052031068763 0.849918340285037 GO:0015294 solute:monoatomic cation symporter activity 12/1774 116/18639 0.103448275862069 1.08690665940987 0.425695717480904 0.849918340285037 GO:0008374 O-acyltransferase activity 6/1774 55/18639 0.109090909090909 1.14619247719586 0.427150315369939 0.849918340285037 GO:0140313 molecular sequestering activity 6/1774 55/18639 0.109090909090909 1.14619247719586 0.427150315369939 0.849918340285037 GO:0004715 non-membrane spanning protein tyrosine kinase activity 5/1774 45/18639 0.111111111111111 1.1674182638106 0.428966397993398 0.849918340285037 GO:0008483 transaminase activity 3/1774 25/18639 0.12 1.26081172491545 0.42986151533122 0.849918340285037 GO:0015296 monoatomic anion:monoatomic cation symporter activity 3/1774 25/18639 0.12 1.26081172491545 0.42986151533122 0.849918340285037 GO:0019706 protein-cysteine S-palmitoyltransferase activity 3/1774 25/18639 0.12 1.26081172491545 0.42986151533122 0.849918340285037 GO:0019707 protein-cysteine S-acyltransferase activity 3/1774 25/18639 0.12 1.26081172491545 0.42986151533122 0.849918340285037 GO:0120020 cholesterol transfer activity 3/1774 25/18639 0.12 1.26081172491545 0.42986151533122 0.849918340285037 GO:0005319 lipid transporter activity 18/1774 178/18639 0.101123595505618 1.06248179065908 0.429896456862462 0.849918340285037 GO:0005343 organic acid:sodium symporter activity 4/1774 35/18639 0.114285714285714 1.20077307134804 0.430162751817733 0.849918340285037 GO:0042826 histone deacetylase binding 13/1774 127/18639 0.102362204724409 1.07549556587276 0.434449802555542 0.855778118635887 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 9/1774 86/18639 0.104651162790698 1.09954510893789 0.434525705952263 0.855778118635887 GO:0098631 cell adhesion mediator activity 8/1774 76/18639 0.105263157894737 1.10597519729425 0.4377247940797 0.85931550119813 GO:0140034 methylation-dependent protein binding 8/1774 76/18639 0.105263157894737 1.10597519729425 0.4377247940797 0.85931550119813 GO:0005539 glycosaminoglycan binding 24/1774 242/18639 0.0991735537190083 1.04199316108714 0.447600729161483 0.877297429156507 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 3/1774 26/18639 0.115384615384615 1.21231896626485 0.455803521011409 0.883136013059711 GO:0015145 monosaccharide transmembrane transporter activity 3/1774 26/18639 0.115384615384615 1.21231896626485 0.455803521011409 0.883136013059711 GO:0016500 protein-hormone receptor activity 7/1774 67/18639 0.104477611940299 1.09772165104579 0.457022534857074 0.883136013059711 GO:0005521 lamin binding 2/1774 16/18639 0.125 1.31334554678692 0.45850979943345 0.883136013059711 GO:0015378 sodium:chloride symporter activity 2/1774 16/18639 0.125 1.31334554678692 0.45850979943345 0.883136013059711 GO:0015562 efflux transmembrane transporter activity 2/1774 16/18639 0.125 1.31334554678692 0.45850979943345 0.883136013059711 GO:0016722 oxidoreductase activity, acting on metal ions 2/1774 16/18639 0.125 1.31334554678692 0.45850979943345 0.883136013059711 GO:0043023 ribosomal large subunit binding 2/1774 16/18639 0.125 1.31334554678692 0.45850979943345 0.883136013059711 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/1774 16/18639 0.125 1.31334554678692 0.45850979943345 0.883136013059711 GO:0055102 lipase inhibitor activity 2/1774 16/18639 0.125 1.31334554678692 0.45850979943345 0.883136013059711 GO:0140328 floppase activity 2/1774 16/18639 0.125 1.31334554678692 0.45850979943345 0.883136013059711 GO:0016504 peptidase activator activity 6/1774 57/18639 0.105263157894737 1.10597519729425 0.461911551760732 0.888291445693714 GO:0008201 heparin binding 17/1774 172/18639 0.0988372093023256 1.03845926955245 0.472664261480355 0.906524123780924 GO:0032934 sterol binding 7/1774 68/18639 0.102941176470588 1.08157868558923 0.472872583751845 0.906524123780924 GO:0019213 deacetylase activity 4/1774 37/18639 0.108108108108108 1.13586641884274 0.473687279724553 0.906667058847778 GO:0005044 scavenger receptor activity 3/1774 27/18639 0.111111111111111 1.1674182638106 0.481233320863013 0.915108890779687 GO:0008266 poly(U) RNA binding 3/1774 27/18639 0.111111111111111 1.1674182638106 0.481233320863013 0.915108890779687 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 3/1774 27/18639 0.111111111111111 1.1674182638106 0.481233320863013 0.915108890779687 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 3/1774 27/18639 0.111111111111111 1.1674182638106 0.481233320863013 0.915108890779687 GO:0033293 monocarboxylic acid binding 8/1774 79/18639 0.10126582278481 1.06397613916915 0.482050738018653 0.915108890779687 GO:0005244 voltage-gated monoatomic ion channel activity 17/1774 173/18639 0.0982658959537572 1.03245661481515 0.482579872198921 0.915108890779687 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 2/1774 17/18639 0.117647058823529 1.23608992638769 0.49085860862963 0.915223433137438 GO:0004549 tRNA-specific ribonuclease activity 2/1774 17/18639 0.117647058823529 1.23608992638769 0.49085860862963 0.915223433137438 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/1774 17/18639 0.117647058823529 1.23608992638769 0.49085860862963 0.915223433137438 GO:0005092 GDP-dissociation inhibitor activity 2/1774 17/18639 0.117647058823529 1.23608992638769 0.49085860862963 0.915223433137438 GO:0008429 phosphatidylethanolamine binding 2/1774 17/18639 0.117647058823529 1.23608992638769 0.49085860862963 0.915223433137438 GO:0008484 sulfuric ester hydrolase activity 2/1774 17/18639 0.117647058823529 1.23608992638769 0.49085860862963 0.915223433137438 GO:0008569 minus-end-directed microtubule motor activity 2/1774 17/18639 0.117647058823529 1.23608992638769 0.49085860862963 0.915223433137438 GO:0015347 sodium-independent organic anion transmembrane transporter activity 2/1774 17/18639 0.117647058823529 1.23608992638769 0.49085860862963 0.915223433137438 GO:0017110 nucleoside diphosphate phosphatase activity 2/1774 17/18639 0.117647058823529 1.23608992638769 0.49085860862963 0.915223433137438 GO:0036041 long-chain fatty acid binding 2/1774 17/18639 0.117647058823529 1.23608992638769 0.49085860862963 0.915223433137438 GO:0070402 NADPH binding 2/1774 17/18639 0.117647058823529 1.23608992638769 0.49085860862963 0.915223433137438 GO:0022832 voltage-gated channel activity 17/1774 175/18639 0.0971428571428571 1.02065711064584 0.502318087257868 0.91981176415773 GO:0005004 GPI-linked ephrin receptor activity 5/1774 49/18639 0.102040816326531 1.07211881370361 0.504972047110157 0.91981176415773 GO:0005008 hepatocyte growth factor receptor activity 5/1774 49/18639 0.102040816326531 1.07211881370361 0.504972047110157 0.91981176415773 GO:0005009 insulin receptor activity 5/1774 49/18639 0.102040816326531 1.07211881370361 0.504972047110157 0.91981176415773 GO:0005011 macrophage colony-stimulating factor receptor activity 5/1774 49/18639 0.102040816326531 1.07211881370361 0.504972047110157 0.91981176415773 GO:0005018 platelet-derived growth factor alpha-receptor activity 5/1774 49/18639 0.102040816326531 1.07211881370361 0.504972047110157 0.91981176415773 GO:0005020 stem cell factor receptor activity 5/1774 49/18639 0.102040816326531 1.07211881370361 0.504972047110157 0.91981176415773 GO:0008288 boss receptor activity 5/1774 49/18639 0.102040816326531 1.07211881370361 0.504972047110157 0.91981176415773 GO:0036332 placental growth factor receptor activity 5/1774 49/18639 0.102040816326531 1.07211881370361 0.504972047110157 0.91981176415773 GO:0038062 protein tyrosine kinase collagen receptor activity 5/1774 49/18639 0.102040816326531 1.07211881370361 0.504972047110157 0.91981176415773 GO:0060175 brain-derived neurotrophic factor receptor activity 5/1774 49/18639 0.102040816326531 1.07211881370361 0.504972047110157 0.91981176415773 GO:0016866 intramolecular transferase activity 3/1774 28/18639 0.107142857142857 1.12572475438879 0.506084186973314 0.91981176415773 GO:0036408 histone H3K14 acetyltransferase activity 3/1774 28/18639 0.107142857142857 1.12572475438879 0.506084186973314 0.91981176415773 GO:0045499 chemorepellent activity 3/1774 28/18639 0.107142857142857 1.12572475438879 0.506084186973314 0.91981176415773 GO:0050698 proteoglycan sulfotransferase activity 3/1774 28/18639 0.107142857142857 1.12572475438879 0.506084186973314 0.91981176415773 GO:0051119 sugar transmembrane transporter activity 3/1774 28/18639 0.107142857142857 1.12572475438879 0.506084186973314 0.91981176415773 GO:0097718 disordered domain specific binding 3/1774 28/18639 0.107142857142857 1.12572475438879 0.506084186973314 0.91981176415773 GO:0015103 inorganic anion transmembrane transporter activity 16/1774 165/18639 0.096969696969697 1.01883775750743 0.507498924514438 0.921016566711388 GO:0030971 receptor tyrosine kinase binding 8/1774 81/18639 0.0987654320987654 1.0377051233872 0.511104934565618 0.92618867580308 GO:0004714 transmembrane receptor protein tyrosine kinase activity 6/1774 60/18639 0.1 1.05067643742954 0.512932240258428 0.927821992176058 GO:0000217 DNA secondary structure binding 4/1774 39/18639 0.102564102564103 1.07761685890209 0.515892782470433 0.927821992176058 GO:0140299 molecular sensor activity 7/1774 71/18639 0.0985915492957746 1.03587817774743 0.519618742494935 0.927821992176058 GO:0008409 5'-3' exonuclease activity 2/1774 18/18639 0.111111111111111 1.1674182638106 0.521958639487775 0.927821992176058 GO:0015172 acidic amino acid transmembrane transporter activity 2/1774 18/18639 0.111111111111111 1.1674182638106 0.521958639487775 0.927821992176058 GO:0015373 monoatomic anion:sodium symporter activity 2/1774 18/18639 0.111111111111111 1.1674182638106 0.521958639487775 0.927821992176058 GO:0017075 syntaxin-1 binding 2/1774 18/18639 0.111111111111111 1.1674182638106 0.521958639487775 0.927821992176058 GO:0098641 cadherin binding involved in cell-cell adhesion 2/1774 18/18639 0.111111111111111 1.1674182638106 0.521958639487775 0.927821992176058 GO:1901611 phosphatidylglycerol binding 2/1774 18/18639 0.111111111111111 1.1674182638106 0.521958639487775 0.927821992176058 GO:1990381 ubiquitin-specific protease binding 2/1774 18/18639 0.111111111111111 1.1674182638106 0.521958639487775 0.927821992176058 GO:0005006 epidermal growth factor receptor activity 5/1774 50/18639 0.1 1.05067643742954 0.523367344158086 0.927821992176058 GO:0005007 fibroblast growth factor receptor activity 5/1774 50/18639 0.1 1.05067643742954 0.523367344158086 0.927821992176058 GO:0005017 platelet-derived growth factor receptor activity 5/1774 50/18639 0.1 1.05067643742954 0.523367344158086 0.927821992176058 GO:0005019 platelet-derived growth factor beta-receptor activity 5/1774 50/18639 0.1 1.05067643742954 0.523367344158086 0.927821992176058 GO:0015605 organophosphate ester transmembrane transporter activity 5/1774 50/18639 0.1 1.05067643742954 0.523367344158086 0.927821992176058 GO:0010484 histone H3 acetyltransferase activity 3/1774 29/18639 0.103448275862069 1.08690665940987 0.530299974138739 0.935247069726367 GO:0016417 S-acyltransferase activity 3/1774 29/18639 0.103448275862069 1.08690665940987 0.530299974138739 0.935247069726367 GO:0099604 ligand-gated calcium channel activity 3/1774 29/18639 0.103448275862069 1.08690665940987 0.530299974138739 0.935247069726367 GO:0051213 dioxygenase activity 9/1774 93/18639 0.0967741935483871 1.01678364912536 0.530609562008021 0.935247069726367 GO:0015144 carbohydrate transmembrane transporter activity 4/1774 40/18639 0.1 1.05067643742954 0.536394952796503 0.941380826899307 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 4/1774 40/18639 0.1 1.05067643742954 0.536394952796503 0.941380826899307 GO:0071949 FAD binding 4/1774 40/18639 0.1 1.05067643742954 0.536394952796503 0.941380826899307 GO:0008135 translation factor activity, RNA binding 8/1774 83/18639 0.0963855421686747 1.01270018065498 0.539606386456107 0.942287615210086 GO:0005021 vascular endothelial growth factor receptor activity 5/1774 51/18639 0.0980392156862745 1.03007493865641 0.5414594425909 0.942287615210086 GO:0005030 neurotrophin receptor activity 5/1774 51/18639 0.0980392156862745 1.03007493865641 0.5414594425909 0.942287615210086 GO:0004521 RNA endonuclease activity 7/1774 73/18639 0.0958904109589041 1.00749795369956 0.549917960528001 0.942287615210086 GO:0003756 protein disulfide isomerase activity 2/1774 19/18639 0.105263157894737 1.10597519729425 0.551754472651218 0.942287615210086 GO:0005346 purine ribonucleotide transmembrane transporter activity 2/1774 19/18639 0.105263157894737 1.10597519729425 0.551754472651218 0.942287615210086 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 2/1774 19/18639 0.105263157894737 1.10597519729425 0.551754472651218 0.942287615210086 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 2/1774 19/18639 0.105263157894737 1.10597519729425 0.551754472651218 0.942287615210086 GO:0030506 ankyrin binding 2/1774 19/18639 0.105263157894737 1.10597519729425 0.551754472651218 0.942287615210086 GO:0031420 alkali metal ion binding 2/1774 19/18639 0.105263157894737 1.10597519729425 0.551754472651218 0.942287615210086 GO:0042577 lipid phosphatase activity 2/1774 19/18639 0.105263157894737 1.10597519729425 0.551754472651218 0.942287615210086 GO:0046624 sphingolipid transporter activity 2/1774 19/18639 0.105263157894737 1.10597519729425 0.551754472651218 0.942287615210086 GO:0097001 ceramide binding 2/1774 19/18639 0.105263157894737 1.10597519729425 0.551754472651218 0.942287615210086 GO:0140036 ubiquitin-modified protein reader activity 2/1774 19/18639 0.105263157894737 1.10597519729425 0.551754472651218 0.942287615210086 GO:1990380 K48-linked deubiquitinase activity 2/1774 19/18639 0.105263157894737 1.10597519729425 0.551754472651218 0.942287615210086 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 3/1774 30/18639 0.1 1.05067643742954 0.553834353429601 0.942287615210086 GO:0008187 poly-pyrimidine tract binding 3/1774 30/18639 0.1 1.05067643742954 0.553834353429601 0.942287615210086 GO:0016769 transferase activity, transferring nitrogenous groups 3/1774 30/18639 0.1 1.05067643742954 0.553834353429601 0.942287615210086 GO:0033612 receptor serine/threonine kinase binding 3/1774 30/18639 0.1 1.05067643742954 0.553834353429601 0.942287615210086 GO:0043995 histone H4K5 acetyltransferase activity 3/1774 30/18639 0.1 1.05067643742954 0.553834353429601 0.942287615210086 GO:0043996 histone H4K8 acetyltransferase activity 3/1774 30/18639 0.1 1.05067643742954 0.553834353429601 0.942287615210086 GO:0043997 histone H4K12 acetyltransferase activity 3/1774 30/18639 0.1 1.05067643742954 0.553834353429601 0.942287615210086 GO:0015291 secondary active transmembrane transporter activity 27/1774 287/18639 0.0940766550522648 0.988441247756011 0.555386116157969 0.943617187647034 GO:0017080 sodium channel regulator activity 4/1774 41/18639 0.0975609756097561 1.02505018285809 0.556450144628522 0.944115550096869 GO:0005261 monoatomic cation channel activity 32/1774 341/18639 0.093841642228739 0.985972023394288 0.561284032735742 0.947723524934064 GO:0005507 copper ion binding 6/1774 63/18639 0.0952380952380952 1.00064422612337 0.56201043900455 0.947723524934064 GO:1901682 sulfur compound transmembrane transporter activity 6/1774 63/18639 0.0952380952380952 1.00064422612337 0.56201043900455 0.947723524934064 GO:0031491 nucleosome binding 7/1774 74/18639 0.0945945945945946 0.993883116487401 0.564756236718796 0.947723524934064 GO:0070851 growth factor receptor binding 13/1774 139/18639 0.0935251798561151 0.982647027811798 0.569070005156468 0.947723524934064 GO:0051879 Hsp90 protein binding 4/1774 42/18639 0.0952380952380952 1.00064422612337 0.57602927239851 0.947723524934064 GO:0004864 protein phosphatase inhibitor activity 5/1774 53/18639 0.0943396226415094 0.991204186254281 0.576635243084697 0.947723524934064 GO:0005003 ephrin receptor activity 5/1774 53/18639 0.0943396226415094 0.991204186254281 0.576635243084697 0.947723524934064 GO:0005005 transmembrane-ephrin receptor activity 5/1774 53/18639 0.0943396226415094 0.991204186254281 0.576635243084697 0.947723524934064 GO:0038064 collagen receptor activity 5/1774 53/18639 0.0943396226415094 0.991204186254281 0.576635243084697 0.947723524934064 GO:1901505 carbohydrate derivative transmembrane transporter activity 5/1774 53/18639 0.0943396226415094 0.991204186254281 0.576635243084697 0.947723524934064 GO:0005310 dicarboxylic acid transmembrane transporter activity 3/1774 31/18639 0.0967741935483871 1.01678364912536 0.576650034695552 0.947723524934064 GO:0016411 acylglycerol O-acyltransferase activity 3/1774 31/18639 0.0967741935483871 1.01678364912536 0.576650034695552 0.947723524934064 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 2/1774 20/18639 0.1 1.05067643742954 0.580212533713445 0.947723524934064 GO:0016004 phospholipase activator activity 2/1774 20/18639 0.1 1.05067643742954 0.580212533713445 0.947723524934064 GO:0031418 L-ascorbic acid binding 2/1774 20/18639 0.1 1.05067643742954 0.580212533713445 0.947723524934064 GO:0061608 nuclear import signal receptor activity 2/1774 20/18639 0.1 1.05067643742954 0.580212533713445 0.947723524934064 GO:0140664 ATP-dependent DNA damage sensor activity 2/1774 20/18639 0.1 1.05067643742954 0.580212533713445 0.947723524934064 GO:0140939 histone H4 methyltransferase activity 2/1774 20/18639 0.1 1.05067643742954 0.580212533713445 0.947723524934064 GO:0050660 flavin adenine dinucleotide binding 8/1774 86/18639 0.0930232558139535 0.977373430167012 0.581069974893079 0.947723524934064 GO:0005496 steroid binding 10/1774 108/18639 0.0925925925925926 0.972848553175498 0.584727299796281 0.947723524934064 GO:0016298 lipase activity 12/1774 130/18639 0.0923076923076923 0.969855173011881 0.588495000911659 0.947723524934064 GO:0120013 lipid transfer activity 6/1774 65/18639 0.0923076923076923 0.969855173011881 0.593379111835656 0.947723524934064 GO:0005249 voltage-gated potassium channel activity 9/1774 98/18639 0.0918367346938776 0.964906932333249 0.595518715744539 0.947723524934064 GO:0120015 sterol transfer activity 3/1774 32/18639 0.09375 0.985009160090192 0.598717992840583 0.947723524934064 GO:0140142 nucleocytoplasmic carrier activity 3/1774 32/18639 0.09375 0.985009160090192 0.598717992840583 0.947723524934064 GO:0015081 sodium ion transmembrane transporter activity 15/1774 164/18639 0.0914634146341463 0.960984546429455 0.603845813576162 0.947723524934064 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 21/1774 229/18639 0.091703056768559 0.963502409869882 0.604790736542684 0.947723524934064 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2/1774 21/18639 0.0952380952380952 1.00064422612337 0.607317440965253 0.947723524934064 GO:0001846 opsonin binding 2/1774 21/18639 0.0952380952380952 1.00064422612337 0.607317440965253 0.947723524934064 GO:0005248 voltage-gated sodium channel activity 2/1774 21/18639 0.0952380952380952 1.00064422612337 0.607317440965253 0.947723524934064 GO:0010314 phosphatidylinositol-5-phosphate binding 2/1774 21/18639 0.0952380952380952 1.00064422612337 0.607317440965253 0.947723524934064 GO:0051428 peptide hormone receptor binding 2/1774 21/18639 0.0952380952380952 1.00064422612337 0.607317440965253 0.947723524934064 GO:0061891 calcium ion sensor activity 2/1774 21/18639 0.0952380952380952 1.00064422612337 0.607317440965253 0.947723524934064 GO:0070182 DNA polymerase binding 2/1774 21/18639 0.0952380952380952 1.00064422612337 0.607317440965253 0.947723524934064 GO:0140312 cargo adaptor activity 2/1774 21/18639 0.0952380952380952 1.00064422612337 0.607317440965253 0.947723524934064 GO:0003697 single-stranded DNA binding 11/1774 121/18639 0.0909090909090909 0.955160397663216 0.609293328530495 0.947723524934064 GO:0004518 nuclease activity 19/1774 209/18639 0.0909090909090909 0.955160397663216 0.618481396814257 0.947723524934064 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 3/1774 33/18639 0.0909090909090909 0.955160397663216 0.620016709428518 0.947723524934064 GO:0019956 chemokine binding 3/1774 33/18639 0.0909090909090909 0.955160397663216 0.620016709428518 0.947723524934064 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 11/1774 122/18639 0.0901639344262295 0.947331214075813 0.620408060449393 0.947723524934064 GO:0008173 RNA methyltransferase activity 6/1774 67/18639 0.0895522388059701 0.940904272324959 0.623519767930435 0.947723524934064 GO:0043021 ribonucleoprotein complex binding 16/1774 177/18639 0.0903954802259887 0.94976401123574 0.623909286807683 0.947723524934064 GO:0019212 phosphatase inhibitor activity 5/1774 56/18639 0.0892857142857143 0.938103961990659 0.626578189953401 0.947723524934064 GO:0008094 ATP-dependent activity, acting on DNA 19/1774 210/18639 0.0904761904761905 0.950612014817201 0.626935735039769 0.947723524934064 GO:0043022 ribosome binding 10/1774 112/18639 0.0892857142857143 0.938103961990659 0.631651657769585 0.947723524934064 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0004935 adrenergic receptor activity 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0008140 cAMP response element binding protein binding 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0008190 eukaryotic initiation factor 4E binding 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0008239 dipeptidyl-peptidase activity 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0008519 ammonium channel activity 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0016427 tRNA (cytidine) methyltransferase activity 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0016868 intramolecular phosphotransferase activity 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0030957 Tat protein binding 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0031419 cobalamin binding 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0032052 bile acid binding 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0032356 oxidized DNA binding 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0043208 glycosphingolipid binding 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0043295 glutathione binding 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0045322 unmethylated CpG binding 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0050308 sugar-phosphatase activity 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0050815 phosphoserine residue binding 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0051378 serotonin binding 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0051880 G-quadruplex DNA binding 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0098505 G-rich strand telomeric DNA binding 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0140999 histone H3K4 trimethyltransferase activity 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:1990757 ubiquitin ligase activator activity 1/1774 10/18639 0.1 1.05067643742954 0.632271710938271 0.947723524934064 GO:0004407 histone deacetylase activity 2/1774 22/18639 0.0909090909090909 0.955160397663216 0.633068849867506 0.947723524934064 GO:0005243 gap junction channel activity 2/1774 22/18639 0.0909090909090909 0.955160397663216 0.633068849867506 0.947723524934064 GO:0008649 rRNA methyltransferase activity 2/1774 22/18639 0.0909090909090909 0.955160397663216 0.633068849867506 0.947723524934064 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 2/1774 22/18639 0.0909090909090909 0.955160397663216 0.633068849867506 0.947723524934064 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/1774 22/18639 0.0909090909090909 0.955160397663216 0.633068849867506 0.947723524934064 GO:0033558 protein lysine deacetylase activity 2/1774 22/18639 0.0909090909090909 0.955160397663216 0.633068849867506 0.947723524934064 GO:0034062 5'-3' RNA polymerase activity 2/1774 22/18639 0.0909090909090909 0.955160397663216 0.633068849867506 0.947723524934064 GO:0097747 RNA polymerase activity 2/1774 22/18639 0.0909090909090909 0.955160397663216 0.633068849867506 0.947723524934064 GO:0140784 metal ion sensor activity 2/1774 22/18639 0.0909090909090909 0.955160397663216 0.633068849867506 0.947723524934064 GO:0016835 carbon-oxygen lyase activity 7/1774 79/18639 0.0886075949367089 0.930979121773008 0.635281521273354 0.947723524934064 GO:0015020 glucuronosyltransferase activity 3/1774 34/18639 0.0882352941176471 0.927067444790769 0.640531438451085 0.947723524934064 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 3/1774 34/18639 0.0882352941176471 0.927067444790769 0.640531438451085 0.947723524934064 GO:0015297 antiporter activity 12/1774 135/18639 0.0888888888888889 0.933934611048478 0.641700856604694 0.947723524934064 GO:0015932 nucleobase-containing compound transmembrane transporter activity 5/1774 57/18639 0.087719298245614 0.921645997745209 0.642411520548849 0.947723524934064 GO:0072341 modified amino acid binding 8/1774 91/18639 0.0879120879120879 0.923671593344649 0.645964654721414 0.947723524934064 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 4/1774 46/18639 0.0869565217391304 0.913631684721337 0.649152828284489 0.947723524934064 GO:0140658 ATP-dependent chromatin remodeler activity 14/1774 158/18639 0.0886075949367089 0.930979121773008 0.651011414142798 0.947723524934064 GO:0099094 ligand-gated monoatomic cation channel activity 12/1774 136/18639 0.0882352941176471 0.927067444790769 0.65189726106909 0.947723524934064 GO:0000295 adenine nucleotide transmembrane transporter activity 2/1774 23/18639 0.0869565217391304 0.913631684721337 0.657478732859973 0.947723524934064 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 2/1774 23/18639 0.0869565217391304 0.913631684721337 0.657478732859973 0.947723524934064 GO:0004602 glutathione peroxidase activity 2/1774 23/18639 0.0869565217391304 0.913631684721337 0.657478732859973 0.947723524934064 GO:0005283 amino acid:sodium symporter activity 2/1774 23/18639 0.0869565217391304 0.913631684721337 0.657478732859973 0.947723524934064 GO:0016917 GABA receptor activity 2/1774 23/18639 0.0869565217391304 0.913631684721337 0.657478732859973 0.947723524934064 GO:0140102 catalytic activity, acting on a rRNA 2/1774 23/18639 0.0869565217391304 0.913631684721337 0.657478732859973 0.947723524934064 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/1774 23/18639 0.0869565217391304 0.913631684721337 0.657478732859973 0.947723524934064 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 16/1774 181/18639 0.0883977900552486 0.928774751318928 0.659706094424024 0.947723524934064 GO:0000175 3'-5'-RNA exonuclease activity 3/1774 35/18639 0.0857142857142857 0.900579803511032 0.660253502822962 0.947723524934064 GO:0005154 epidermal growth factor receptor binding 3/1774 35/18639 0.0857142857142857 0.900579803511032 0.660253502822962 0.947723524934064 GO:0010485 histone H4 acetyltransferase activity 3/1774 35/18639 0.0857142857142857 0.900579803511032 0.660253502822962 0.947723524934064 GO:0034061 DNA polymerase activity 3/1774 35/18639 0.0857142857142857 0.900579803511032 0.660253502822962 0.947723524934064 GO:0008514 organic anion transmembrane transporter activity 24/1774 269/18639 0.0892193308550186 0.937406486925982 0.661828944272284 0.947723524934064 GO:0005504 fatty acid binding 4/1774 47/18639 0.0851063829787234 0.89419271270599 0.666061222198378 0.947723524934064 GO:0043495 protein-membrane adaptor activity 4/1774 47/18639 0.0851063829787234 0.89419271270599 0.666061222198378 0.947723524934064 GO:0061733 protein-lysine-acetyltransferase activity 4/1774 47/18639 0.0851063829787234 0.89419271270599 0.666061222198378 0.947723524934064 GO:0061749 forked DNA-dependent helicase activity 4/1774 47/18639 0.0851063829787234 0.89419271270599 0.666061222198378 0.947723524934064 GO:0099095 ligand-gated monoatomic anion channel activity 4/1774 47/18639 0.0851063829787234 0.89419271270599 0.666061222198378 0.947723524934064 GO:1990518 single-stranded 3'-5' DNA helicase activity 4/1774 47/18639 0.0851063829787234 0.89419271270599 0.666061222198378 0.947723524934064 GO:0016782 transferase activity, transferring sulphur-containing groups 6/1774 70/18639 0.0857142857142857 0.900579803511032 0.666224855244168 0.947723524934064 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/1774 11/18639 0.0909090909090909 0.955160397663216 0.667289692837219 0.947723524934064 GO:0001851 complement component C3b binding 1/1774 11/18639 0.0909090909090909 0.955160397663216 0.667289692837219 0.947723524934064 GO:0003953 NAD+ nucleosidase activity 1/1774 11/18639 0.0909090909090909 0.955160397663216 0.667289692837219 0.947723524934064 GO:0005225 volume-sensitive anion channel activity 1/1774 11/18639 0.0909090909090909 0.955160397663216 0.667289692837219 0.947723524934064 GO:0008046 axon guidance receptor activity 1/1774 11/18639 0.0909090909090909 0.955160397663216 0.667289692837219 0.947723524934064 GO:0008199 ferric iron binding 1/1774 11/18639 0.0909090909090909 0.955160397663216 0.667289692837219 0.947723524934064 GO:0015173 aromatic amino acid transmembrane transporter activity 1/1774 11/18639 0.0909090909090909 0.955160397663216 0.667289692837219 0.947723524934064 GO:0015217 ADP transmembrane transporter activity 1/1774 11/18639 0.0909090909090909 0.955160397663216 0.667289692837219 0.947723524934064 GO:0032404 mismatch repair complex binding 1/1774 11/18639 0.0909090909090909 0.955160397663216 0.667289692837219 0.947723524934064 GO:0032794 GTPase activating protein binding 1/1774 11/18639 0.0909090909090909 0.955160397663216 0.667289692837219 0.947723524934064 GO:0047676 arachidonate-CoA ligase activity 1/1774 11/18639 0.0909090909090909 0.955160397663216 0.667289692837219 0.947723524934064 GO:0048407 platelet-derived growth factor binding 1/1774 11/18639 0.0909090909090909 0.955160397663216 0.667289692837219 0.947723524934064 GO:0097493 structural molecule activity conferring elasticity 1/1774 11/18639 0.0909090909090909 0.955160397663216 0.667289692837219 0.947723524934064 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/1774 11/18639 0.0909090909090909 0.955160397663216 0.667289692837219 0.947723524934064 GO:0140537 transcription regulator activator activity 1/1774 11/18639 0.0909090909090909 0.955160397663216 0.667289692837219 0.947723524934064 GO:1900750 oligopeptide binding 1/1774 11/18639 0.0909090909090909 0.955160397663216 0.667289692837219 0.947723524934064 GO:0008509 monoatomic anion transmembrane transporter activity 13/1774 149/18639 0.087248322147651 0.916697562857986 0.670532937130376 0.947723524934064 GO:0140097 catalytic activity, acting on DNA 30/1774 336/18639 0.0892857142857143 0.938103961990659 0.672082169364408 0.947723524934064 GO:0001786 phosphatidylserine binding 5/1774 59/18639 0.0847457627118644 0.890403760533507 0.672791721997452 0.947723524934064 GO:0070888 E-box binding 5/1774 59/18639 0.0847457627118644 0.890403760533507 0.672791721997452 0.947723524934064 GO:0004519 endonuclease activity 11/1774 127/18639 0.0866141732283465 0.910034709584639 0.673471966460084 0.947723524934064 GO:0046982 protein heterodimerization activity 33/1774 369/18639 0.0894308943089431 0.939629334286579 0.674032616283555 0.947723524934064 GO:0019842 vitamin binding 13/1774 150/18639 0.0866666666666667 0.910586245772266 0.679906475833961 0.947723524934064 GO:0004622 lysophospholipase activity 2/1774 24/18639 0.0833333333333333 0.875563697857948 0.680569040293162 0.947723524934064 GO:0004806 triacylglycerol lipase activity 2/1774 24/18639 0.0833333333333333 0.875563697857948 0.680569040293162 0.947723524934064 GO:0015149 hexose transmembrane transporter activity 2/1774 24/18639 0.0833333333333333 0.875563697857948 0.680569040293162 0.947723524934064 GO:0015295 solute:proton symporter activity 2/1774 24/18639 0.0833333333333333 0.875563697857948 0.680569040293162 0.947723524934064 GO:0030215 semaphorin receptor binding 2/1774 24/18639 0.0833333333333333 0.875563697857948 0.680569040293162 0.947723524934064 GO:0042625 ATPase-coupled ion transmembrane transporter activity 2/1774 24/18639 0.0833333333333333 0.875563697857948 0.680569040293162 0.947723524934064 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 2/1774 24/18639 0.0833333333333333 0.875563697857948 0.680569040293162 0.947723524934064 GO:0046961 proton-transporting ATPase activity, rotational mechanism 2/1774 24/18639 0.0833333333333333 0.875563697857948 0.680569040293162 0.947723524934064 GO:0055056 D-glucose transmembrane transporter activity 2/1774 24/18639 0.0833333333333333 0.875563697857948 0.680569040293162 0.947723524934064 GO:0060229 lipase activator activity 2/1774 24/18639 0.0833333333333333 0.875563697857948 0.680569040293162 0.947723524934064 GO:0140612 DNA damage sensor activity 2/1774 24/18639 0.0833333333333333 0.875563697857948 0.680569040293162 0.947723524934064 GO:0016410 N-acyltransferase activity 8/1774 94/18639 0.0851063829787234 0.89419271270599 0.681993432215687 0.947723524934064 GO:0009378 four-way junction helicase activity 4/1774 48/18639 0.0833333333333333 0.875563697857948 0.682402990791069 0.947723524934064 GO:0036121 double-stranded DNA helicase activity 4/1774 48/18639 0.0833333333333333 0.875563697857948 0.682402990791069 0.947723524934064 GO:0043138 3'-5' DNA helicase activity 4/1774 48/18639 0.0833333333333333 0.875563697857948 0.682402990791069 0.947723524934064 GO:0140693 molecular condensate scaffold activity 4/1774 48/18639 0.0833333333333333 0.875563697857948 0.682402990791069 0.947723524934064 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 5/1774 60/18639 0.0833333333333333 0.875563697857948 0.687324402155545 0.947723524934064 GO:0004497 monooxygenase activity 9/1774 106/18639 0.0849056603773585 0.892083767628853 0.68935676673275 0.947723524934064 GO:0060590 ATPase regulator activity 4/1774 49/18639 0.0816326530612245 0.857695050962888 0.698174630229372 0.947723524934064 GO:0000340 RNA 7-methylguanosine cap binding 1/1774 12/18639 0.0833333333333333 0.875563697857948 0.698974687732364 0.947723524934064 GO:0004526 ribonuclease P activity 1/1774 12/18639 0.0833333333333333 0.875563697857948 0.698974687732364 0.947723524934064 GO:0004875 complement receptor activity 1/1774 12/18639 0.0833333333333333 0.875563697857948 0.698974687732364 0.947723524934064 GO:0005049 nuclear export signal receptor activity 1/1774 12/18639 0.0833333333333333 0.875563697857948 0.698974687732364 0.947723524934064 GO:0005165 neurotrophin receptor binding 1/1774 12/18639 0.0833333333333333 0.875563697857948 0.698974687732364 0.947723524934064 GO:0005247 voltage-gated chloride channel activity 1/1774 12/18639 0.0833333333333333 0.875563697857948 0.698974687732364 0.947723524934064 GO:0010853 cyclase activator activity 1/1774 12/18639 0.0833333333333333 0.875563697857948 0.698974687732364 0.947723524934064 GO:0016273 arginine N-methyltransferase activity 1/1774 12/18639 0.0833333333333333 0.875563697857948 0.698974687732364 0.947723524934064 GO:0016274 protein-arginine N-methyltransferase activity 1/1774 12/18639 0.0833333333333333 0.875563697857948 0.698974687732364 0.947723524934064 GO:0031543 peptidyl-proline dioxygenase activity 1/1774 12/18639 0.0833333333333333 0.875563697857948 0.698974687732364 0.947723524934064 GO:0035197 siRNA binding 1/1774 12/18639 0.0833333333333333 0.875563697857948 0.698974687732364 0.947723524934064 GO:0042301 phosphate ion binding 1/1774 12/18639 0.0833333333333333 0.875563697857948 0.698974687732364 0.947723524934064 GO:0043047 single-stranded telomeric DNA binding 1/1774 12/18639 0.0833333333333333 0.875563697857948 0.698974687732364 0.947723524934064 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/1774 12/18639 0.0833333333333333 0.875563697857948 0.698974687732364 0.947723524934064 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/1774 12/18639 0.0833333333333333 0.875563697857948 0.698974687732364 0.947723524934064 GO:0070008 serine-type exopeptidase activity 1/1774 12/18639 0.0833333333333333 0.875563697857948 0.698974687732364 0.947723524934064 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/1774 12/18639 0.0833333333333333 0.875563697857948 0.698974687732364 0.947723524934064 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/1774 12/18639 0.0833333333333333 0.875563697857948 0.698974687732364 0.947723524934064 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/1774 12/18639 0.0833333333333333 0.875563697857948 0.698974687732364 0.947723524934064 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/1774 12/18639 0.0833333333333333 0.875563697857948 0.698974687732364 0.947723524934064 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/1774 12/18639 0.0833333333333333 0.875563697857948 0.698974687732364 0.947723524934064 GO:1990817 poly(A) RNA polymerase activity 1/1774 12/18639 0.0833333333333333 0.875563697857948 0.698974687732364 0.947723524934064 GO:0015662 P-type ion transporter activity 2/1774 25/18639 0.08 0.84054114994363 0.702369694637679 0.947723524934064 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 2/1774 25/18639 0.08 0.84054114994363 0.702369694637679 0.947723524934064 GO:0047617 fatty acyl-CoA hydrolase activity 2/1774 25/18639 0.08 0.84054114994363 0.702369694637679 0.947723524934064 GO:0140358 P-type transmembrane transporter activity 2/1774 25/18639 0.08 0.84054114994363 0.702369694637679 0.947723524934064 GO:1901681 sulfur compound binding 24/1774 275/18639 0.0872727272727273 0.916953981756688 0.703435803310574 0.947723524934064 GO:0016407 acetyltransferase activity 8/1774 96/18639 0.0833333333333333 0.875563697857948 0.704703272821821 0.947723524934064 GO:0005109 frizzled binding 3/1774 38/18639 0.0789473684210526 0.829481397970688 0.714654213073693 0.947723524934064 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 3/1774 38/18639 0.0789473684210526 0.829481397970688 0.714654213073693 0.947723524934064 GO:0042887 amide transmembrane transporter activity 3/1774 38/18639 0.0789473684210526 0.829481397970688 0.714654213073693 0.947723524934064 GO:0140597 protein carrier chaperone 16/1774 188/18639 0.0851063829787234 0.89419271270599 0.717707730598611 0.947723524934064 GO:0003684 damaged DNA binding 6/1774 74/18639 0.0810810810810811 0.851899814132058 0.718176093781621 0.947723524934064 GO:0004620 phospholipase activity 9/1774 109/18639 0.0825688073394495 0.867531003382187 0.720814325645575 0.947723524934064 GO:0004529 DNA exonuclease activity 2/1774 26/18639 0.0769230769230769 0.808212644176568 0.722916875773201 0.947723524934064 GO:0005112 Notch binding 2/1774 26/18639 0.0769230769230769 0.808212644176568 0.722916875773201 0.947723524934064 GO:0008066 glutamate receptor activity 2/1774 26/18639 0.0769230769230769 0.808212644176568 0.722916875773201 0.947723524934064 GO:0008143 poly(A) binding 2/1774 26/18639 0.0769230769230769 0.808212644176568 0.722916875773201 0.947723524934064 GO:0008198 ferrous iron binding 2/1774 26/18639 0.0769230769230769 0.808212644176568 0.722916875773201 0.947723524934064 GO:0015216 purine nucleotide transmembrane transporter activity 2/1774 26/18639 0.0769230769230769 0.808212644176568 0.722916875773201 0.947723524934064 GO:0016289 acyl-CoA hydrolase activity 2/1774 26/18639 0.0769230769230769 0.808212644176568 0.722916875773201 0.947723524934064 GO:0034237 protein kinase A regulatory subunit binding 2/1774 26/18639 0.0769230769230769 0.808212644176568 0.722916875773201 0.947723524934064 GO:0120014 phospholipid transfer activity 2/1774 26/18639 0.0769230769230769 0.808212644176568 0.722916875773201 0.947723524934064 GO:0004386 helicase activity 13/1774 155/18639 0.0838709677419355 0.881212495908645 0.724394700586004 0.947723524934064 GO:0004540 RNA nuclease activity 10/1774 121/18639 0.0826446280991736 0.868327634239287 0.72597281020518 0.947723524934064 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/1774 13/18639 0.0769230769230769 0.808212644176568 0.727643765091187 0.947723524934064 GO:0004993 G protein-coupled serotonin receptor activity 1/1774 13/18639 0.0769230769230769 0.808212644176568 0.727643765091187 0.947723524934064 GO:0005542 folic acid binding 1/1774 13/18639 0.0769230769230769 0.808212644176568 0.727643765091187 0.947723524934064 GO:0008417 fucosyltransferase activity 1/1774 13/18639 0.0769230769230769 0.808212644176568 0.727643765091187 0.947723524934064 GO:0009982 pseudouridine synthase activity 1/1774 13/18639 0.0769230769230769 0.808212644176568 0.727643765091187 0.947723524934064 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/1774 13/18639 0.0769230769230769 0.808212644176568 0.727643765091187 0.947723524934064 GO:0017154 semaphorin receptor activity 1/1774 13/18639 0.0769230769230769 0.808212644176568 0.727643765091187 0.947723524934064 GO:0030955 potassium ion binding 1/1774 13/18639 0.0769230769230769 0.808212644176568 0.727643765091187 0.947723524934064 GO:0031432 titin binding 1/1774 13/18639 0.0769230769230769 0.808212644176568 0.727643765091187 0.947723524934064 GO:0039706 co-receptor binding 1/1774 13/18639 0.0769230769230769 0.808212644176568 0.727643765091187 0.947723524934064 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/1774 13/18639 0.0769230769230769 0.808212644176568 0.727643765091187 0.947723524934064 GO:0051011 microtubule minus-end binding 1/1774 13/18639 0.0769230769230769 0.808212644176568 0.727643765091187 0.947723524934064 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/1774 13/18639 0.0769230769230769 0.808212644176568 0.727643765091187 0.947723524934064 GO:0061459 L-arginine transmembrane transporter activity 1/1774 13/18639 0.0769230769230769 0.808212644176568 0.727643765091187 0.947723524934064 GO:0070700 BMP receptor binding 1/1774 13/18639 0.0769230769230769 0.808212644176568 0.727643765091187 0.947723524934064 GO:0140666 annealing activity 1/1774 13/18639 0.0769230769230769 0.808212644176568 0.727643765091187 0.947723524934064 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/1774 13/18639 0.0769230769230769 0.808212644176568 0.727643765091187 0.947723524934064 GO:0140852 histone ubiquitin ligase activity 1/1774 13/18639 0.0769230769230769 0.808212644176568 0.727643765091187 0.947723524934064 GO:0016597 amino acid binding 4/1774 51/18639 0.0784313725490196 0.824059950925128 0.728006397520779 0.947723524934064 GO:0030544 Hsp70 protein binding 4/1774 51/18639 0.0784313725490196 0.824059950925128 0.728006397520779 0.947723524934064 GO:0044183 protein folding chaperone 6/1774 75/18639 0.08 0.84054114994363 0.730246461533394 0.949630483416569 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 3/1774 39/18639 0.0769230769230769 0.808212644176568 0.731217665623965 0.94988509055075 GO:0030246 carbohydrate binding 24/1774 280/18639 0.0857142857142857 0.900579803511032 0.735770998153296 0.951265629871886 GO:0051536 iron-sulfur cluster binding 6/1774 76/18639 0.0789473684210526 0.829481397970688 0.741947328231542 0.951265629871886 GO:0004364 glutathione transferase activity 2/1774 27/18639 0.0740740740740741 0.778278842540398 0.742251560166017 0.951265629871886 GO:0005385 zinc ion transmembrane transporter activity 2/1774 27/18639 0.0740740740740741 0.778278842540398 0.742251560166017 0.951265629871886 GO:0008395 steroid hydroxylase activity 2/1774 27/18639 0.0740740740740741 0.778278842540398 0.742251560166017 0.951265629871886 GO:0004197 cysteine-type endopeptidase activity 7/1774 88/18639 0.0795454545454545 0.835765347955314 0.744060748577228 0.951265629871886 GO:0004532 RNA exonuclease activity 3/1774 40/18639 0.075 0.788007328072153 0.747014101799164 0.951265629871886 GO:0042277 peptide binding 21/1774 249/18639 0.0843373493975904 0.886112658073104 0.751926357088476 0.951265629871886 GO:0140104 molecular carrier activity 21/1774 249/18639 0.0843373493975904 0.886112658073104 0.751926357088476 0.951265629871886 GO:0051540 metal cluster binding 6/1774 77/18639 0.0779220779220779 0.818708912282757 0.753279290472688 0.951265629871886 GO:0005344 oxygen carrier activity 1/1774 14/18639 0.0714285714285714 0.750483169592527 0.753583846736641 0.951265629871886 GO:0008474 palmitoyl-(protein) hydrolase activity 1/1774 14/18639 0.0714285714285714 0.750483169592527 0.753583846736641 0.951265629871886 GO:0008494 translation activator activity 1/1774 14/18639 0.0714285714285714 0.750483169592527 0.753583846736641 0.951265629871886 GO:0008559 ABC-type xenobiotic transporter activity 1/1774 14/18639 0.0714285714285714 0.750483169592527 0.753583846736641 0.951265629871886 GO:0016530 metallochaperone activity 1/1774 14/18639 0.0714285714285714 0.750483169592527 0.753583846736641 0.951265629871886 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 1/1774 14/18639 0.0714285714285714 0.750483169592527 0.753583846736641 0.951265629871886 GO:0032036 myosin heavy chain binding 1/1774 14/18639 0.0714285714285714 0.750483169592527 0.753583846736641 0.951265629871886 GO:0043176 amine binding 1/1774 14/18639 0.0714285714285714 0.750483169592527 0.753583846736641 0.951265629871886 GO:0044548 S100 protein binding 1/1774 14/18639 0.0714285714285714 0.750483169592527 0.753583846736641 0.951265629871886 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/1774 14/18639 0.0714285714285714 0.750483169592527 0.753583846736641 0.951265629871886 GO:0061665 SUMO ligase activity 1/1774 14/18639 0.0714285714285714 0.750483169592527 0.753583846736641 0.951265629871886 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/1774 14/18639 0.0714285714285714 0.750483169592527 0.753583846736641 0.951265629871886 GO:0098599 palmitoyl hydrolase activity 1/1774 14/18639 0.0714285714285714 0.750483169592527 0.753583846736641 0.951265629871886 GO:1901474 azole transmembrane transporter activity 1/1774 14/18639 0.0714285714285714 0.750483169592527 0.753583846736641 0.951265629871886 GO:1901612 cardiolipin binding 1/1774 14/18639 0.0714285714285714 0.750483169592527 0.753583846736641 0.951265629871886 GO:0005267 potassium channel activity 10/1774 124/18639 0.0806451612903226 0.847319707604466 0.753592131354469 0.951265629871886 GO:0003727 single-stranded RNA binding 7/1774 89/18639 0.0786516853932584 0.826374726068176 0.754591787342629 0.951265629871886 GO:0008146 sulfotransferase activity 4/1774 53/18639 0.0754716981132075 0.792963349003425 0.755576700298241 0.951265629871886 GO:0016860 intramolecular oxidoreductase activity 4/1774 53/18639 0.0754716981132075 0.792963349003425 0.755576700298241 0.951265629871886 GO:0034212 protein N-acetyltransferase activity 4/1774 53/18639 0.0754716981132075 0.792963349003425 0.755576700298241 0.951265629871886 GO:0005242 inward rectifier potassium channel activity 2/1774 28/18639 0.0714285714285714 0.750483169592527 0.76041828118084 0.953546287332757 GO:0019789 SUMO transferase activity 2/1774 28/18639 0.0714285714285714 0.750483169592527 0.76041828118084 0.953546287332757 GO:0046625 sphingolipid binding 2/1774 28/18639 0.0714285714285714 0.750483169592527 0.76041828118084 0.953546287332757 GO:0015175 neutral L-amino acid transmembrane transporter activity 3/1774 41/18639 0.0731707317073171 0.768787637143564 0.762058624733689 0.953546287332757 GO:0016877 ligase activity, forming carbon-sulfur bonds 3/1774 41/18639 0.0731707317073171 0.768787637143564 0.762058624733689 0.953546287332757 GO:0140828 metal cation:monoatomic cation antiporter activity 3/1774 41/18639 0.0731707317073171 0.768787637143564 0.762058624733689 0.953546287332757 GO:0015079 potassium ion transmembrane transporter activity 13/1774 160/18639 0.08125 0.853674605411499 0.764749250445544 0.955126966426274 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 4/1774 54/18639 0.0740740740740741 0.778278842540398 0.768528726746118 0.955126966426274 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 4/1774 54/18639 0.0740740740740741 0.778278842540398 0.768528726746118 0.955126966426274 GO:0051287 NAD binding 4/1774 54/18639 0.0740740740740741 0.778278842540398 0.768528726746118 0.955126966426274 GO:0140098 catalytic activity, acting on RNA 33/1774 387/18639 0.0852713178294574 0.895925644319761 0.773056585573946 0.955126966426274 GO:0004402 histone acetyltransferase activity 3/1774 42/18639 0.0714285714285714 0.750483169592527 0.776368574913318 0.955126966426274 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 5/1774 67/18639 0.0746268656716418 0.784086893604133 0.776576142293467 0.955126966426274 GO:0004089 carbonate dehydratase activity 1/1774 15/18639 0.0666666666666667 0.700450958286359 0.777054571885055 0.955126966426274 GO:0004467 long-chain fatty acid-CoA ligase activity 1/1774 15/18639 0.0666666666666667 0.700450958286359 0.777054571885055 0.955126966426274 GO:0010181 FMN binding 1/1774 15/18639 0.0666666666666667 0.700450958286359 0.777054571885055 0.955126966426274 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1/1774 15/18639 0.0666666666666667 0.700450958286359 0.777054571885055 0.955126966426274 GO:0016846 carbon-sulfur lyase activity 1/1774 15/18639 0.0666666666666667 0.700450958286359 0.777054571885055 0.955126966426274 GO:0033130 acetylcholine receptor binding 1/1774 15/18639 0.0666666666666667 0.700450958286359 0.777054571885055 0.955126966426274 GO:0034483 heparan sulfate sulfotransferase activity 1/1774 15/18639 0.0666666666666667 0.700450958286359 0.777054571885055 0.955126966426274 GO:0042809 nuclear vitamin D receptor binding 1/1774 15/18639 0.0666666666666667 0.700450958286359 0.777054571885055 0.955126966426274 GO:0140161 monocarboxylate:sodium symporter activity 1/1774 15/18639 0.0666666666666667 0.700450958286359 0.777054571885055 0.955126966426274 GO:0005416 amino acid:monoatomic cation symporter activity 2/1774 29/18639 0.0689655172413793 0.724604439606578 0.777464081702477 0.955126966426274 GO:0106222 lncRNA binding 2/1774 29/18639 0.0689655172413793 0.724604439606578 0.777464081702477 0.955126966426274 GO:0000510 H3-H4 histone complex chaperone activity 12/1774 151/18639 0.0794701986754967 0.834974652261884 0.784189679264082 0.955126966426274 GO:0140584 chromatin extrusion motor activity 12/1774 151/18639 0.0794701986754967 0.834974652261884 0.784189679264082 0.955126966426274 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 12/1774 151/18639 0.0794701986754967 0.834974652261884 0.784189679264082 0.955126966426274 GO:0140849 ATP-dependent H2AZ histone chaperone activity 12/1774 151/18639 0.0794701986754967 0.834974652261884 0.784189679264082 0.955126966426274 GO:0015276 ligand-gated monoatomic ion channel activity 15/1774 186/18639 0.0806451612903226 0.847319707604466 0.786038676890477 0.955126966426274 GO:0031490 chromatin DNA binding 10/1774 128/18639 0.078125 0.820840966741826 0.787343375453933 0.955126966426274 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 3/1774 43/18639 0.0697674418604651 0.733030072625259 0.789963143005406 0.955126966426274 GO:0015616 DNA translocase activity 12/1774 152/18639 0.0789473684210526 0.829481397970688 0.791561521242277 0.955126966426274 GO:0140674 ATP-dependent histone chaperone activity 12/1774 152/18639 0.0789473684210526 0.829481397970688 0.791561521242277 0.955126966426274 GO:0031406 carboxylic acid binding 15/1774 187/18639 0.0802139037433155 0.842788586173426 0.792686794925264 0.955126966426274 GO:0030170 pyridoxal phosphate binding 4/1774 56/18639 0.0714285714285714 0.750483169592527 0.792810270436579 0.955126966426274 GO:0170055 lipid transmembrane transporter activity 4/1774 56/18639 0.0714285714285714 0.750483169592527 0.792810270436579 0.955126966426274 GO:0015215 nucleotide transmembrane transporter activity 2/1774 30/18639 0.0666666666666667 0.700450958286359 0.793437633721968 0.955126966426274 GO:0140713 histone chaperone activity 13/1774 164/18639 0.0792682926829268 0.832853273572195 0.793986279023764 0.955126966426274 GO:0005216 monoatomic ion channel activity 38/1774 448/18639 0.0848214285714286 0.891198763891126 0.797136736032685 0.955126966426274 GO:0008080 N-acetyltransferase activity 5/1774 69/18639 0.072463768115942 0.761359737267781 0.798131287012262 0.955126966426274 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 1/1774 16/18639 0.0625 0.656672773393461 0.798290890048495 0.955126966426274 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/1774 16/18639 0.0625 0.656672773393461 0.798290890048495 0.955126966426274 GO:0008296 3'-5'-DNA exonuclease activity 1/1774 16/18639 0.0625 0.656672773393461 0.798290890048495 0.955126966426274 GO:0015385 sodium:proton antiporter activity 1/1774 16/18639 0.0625 0.656672773393461 0.798290890048495 0.955126966426274 GO:0017070 U6 snRNA binding 1/1774 16/18639 0.0625 0.656672773393461 0.798290890048495 0.955126966426274 GO:0022841 potassium ion leak channel activity 1/1774 16/18639 0.0625 0.656672773393461 0.798290890048495 0.955126966426274 GO:0022858 alanine transmembrane transporter activity 1/1774 16/18639 0.0625 0.656672773393461 0.798290890048495 0.955126966426274 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/1774 16/18639 0.0625 0.656672773393461 0.798290890048495 0.955126966426274 GO:0097027 ubiquitin-protein transferase activator activity 1/1774 16/18639 0.0625 0.656672773393461 0.798290890048495 0.955126966426274 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/1774 16/18639 0.0625 0.656672773393461 0.798290890048495 0.955126966426274 GO:0061775 cohesin loader activity 12/1774 153/18639 0.0784313725490196 0.824059950925128 0.798751045902299 0.955126966426274 GO:0022834 ligand-gated channel activity 15/1774 188/18639 0.0797872340425532 0.838305668161865 0.799187869866882 0.955126966426274 GO:0016790 thiolester hydrolase activity 3/1774 44/18639 0.0681818181818182 0.716370298247412 0.802863019389028 0.958265925456002 GO:0004601 peroxidase activity 4/1774 57/18639 0.0701754385964912 0.737316798196167 0.80416111948471 0.958265925456002 GO:0070279 vitamin B6 binding 4/1774 57/18639 0.0701754385964912 0.737316798196167 0.80416111948471 0.958265925456002 GO:0043177 organic acid binding 15/1774 189/18639 0.0793650793650794 0.833870188436141 0.805542382399919 0.958979026666571 GO:0004867 serine-type endopeptidase inhibitor activity 7/1774 95/18639 0.0736842105263158 0.774182638105975 0.811245218149038 0.963096565336455 GO:0017116 single-stranded DNA helicase activity 4/1774 58/18639 0.0689655172413793 0.724604439606578 0.815001296387526 0.963096565336455 GO:0046915 transition metal ion transmembrane transporter activity 3/1774 45/18639 0.0666666666666667 0.700450958286359 0.815090078496359 0.963096565336455 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/1774 17/18639 0.0588235294117647 0.618044963193846 0.817505407637174 0.963096565336455 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/1774 17/18639 0.0588235294117647 0.618044963193846 0.817505407637174 0.963096565336455 GO:0045125 bioactive lipid receptor activity 1/1774 17/18639 0.0588235294117647 0.618044963193846 0.817505407637174 0.963096565336455 GO:0045236 CXCR chemokine receptor binding 1/1774 17/18639 0.0588235294117647 0.618044963193846 0.817505407637174 0.963096565336455 GO:0051787 misfolded protein binding 1/1774 17/18639 0.0588235294117647 0.618044963193846 0.817505407637174 0.963096565336455 GO:0070403 NAD+ binding 1/1774 17/18639 0.0588235294117647 0.618044963193846 0.817505407637174 0.963096565336455 GO:0070492 oligosaccharide binding 1/1774 17/18639 0.0588235294117647 0.618044963193846 0.817505407637174 0.963096565336455 GO:0061134 peptidase regulator activity 18/1774 226/18639 0.079646017699115 0.836821941315561 0.818675882995316 0.963096565336455 GO:0022836 gated channel activity 26/1774 318/18639 0.0817610062893082 0.859043628087043 0.819976232941003 0.963096565336455 GO:0016853 isomerase activity 14/1774 180/18639 0.0777777777777778 0.817192784667418 0.822046280746127 0.963096565336455 GO:0015106 bicarbonate transmembrane transporter activity 2/1774 32/18639 0.0625 0.656672773393461 0.822366536605659 0.963096565336455 GO:0042910 xenobiotic transmembrane transporter activity 2/1774 32/18639 0.0625 0.656672773393461 0.822366536605659 0.963096565336455 GO:0043425 bHLH transcription factor binding 2/1774 32/18639 0.0625 0.656672773393461 0.822366536605659 0.963096565336455 GO:0051059 NF-kappaB binding 2/1774 32/18639 0.0625 0.656672773393461 0.822366536605659 0.963096565336455 GO:0015108 chloride transmembrane transporter activity 9/1774 121/18639 0.0743801652892562 0.781494870815359 0.824862330438773 0.963625604665253 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 4/1774 59/18639 0.0677966101694915 0.712323008426805 0.825343810888622 0.963625604665253 GO:0036002 pre-mRNA binding 4/1774 59/18639 0.0677966101694915 0.712323008426805 0.825343810888622 0.963625604665253 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 3/1774 46/18639 0.0652173913043478 0.685223763541003 0.826667095953002 0.963625604665253 GO:0030414 peptidase inhibitor activity 13/1774 169/18639 0.0769230769230769 0.808212644176568 0.826751437145454 0.963625604665253 GO:0008528 G protein-coupled peptide receptor activity 9/1774 122/18639 0.0737704918032787 0.775089175152938 0.831987789424032 0.963747246005202 GO:0005126 cytokine receptor binding 22/1774 275/18639 0.08 0.84054114994363 0.833152218557289 0.963747246005202 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/1774 18/18639 0.0555555555555556 0.583709131905299 0.834890511645962 0.963747246005202 GO:0004970 glutamate-gated receptor activity 1/1774 18/18639 0.0555555555555556 0.583709131905299 0.834890511645962 0.963747246005202 GO:0008308 voltage-gated monoatomic anion channel activity 1/1774 18/18639 0.0555555555555556 0.583709131905299 0.834890511645962 0.963747246005202 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/1774 18/18639 0.0555555555555556 0.583709131905299 0.834890511645962 0.963747246005202 GO:0035615 clathrin adaptor activity 1/1774 18/18639 0.0555555555555556 0.583709131905299 0.834890511645962 0.963747246005202 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/1774 18/18639 0.0555555555555556 0.583709131905299 0.834890511645962 0.963747246005202 GO:0030296 protein tyrosine kinase activator activity 2/1774 33/18639 0.0606060606060606 0.636773598442144 0.835421364165475 0.963747246005202 GO:0140416 transcription regulator inhibitor activity 2/1774 33/18639 0.0606060606060606 0.636773598442144 0.835421364165475 0.963747246005202 GO:0042626 ATPase-coupled transmembrane transporter activity 7/1774 98/18639 0.0714285714285714 0.750483169592527 0.835509857353082 0.963747246005202 GO:0016209 antioxidant activity 6/1774 86/18639 0.0697674418604651 0.733030072625259 0.839176227668592 0.964823941849899 GO:0003689 DNA clamp loader activity 12/1774 160/18639 0.075 0.788007328072153 0.84407294318753 0.964823941849899 GO:0048029 monosaccharide binding 5/1774 74/18639 0.0675675675675676 0.709916511776715 0.844850134093477 0.964823941849899 GO:0015035 protein-disulfide reductase activity 2/1774 34/18639 0.0588235294117647 0.618044963193846 0.847601984522624 0.964823941849899 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 2/1774 34/18639 0.0588235294117647 0.618044963193846 0.847601984522624 0.964823941849899 GO:0019825 oxygen binding 2/1774 34/18639 0.0588235294117647 0.618044963193846 0.847601984522624 0.964823941849899 GO:0051427 hormone receptor binding 2/1774 34/18639 0.0588235294117647 0.618044963193846 0.847601984522624 0.964823941849899 GO:0004866 endopeptidase inhibitor activity 12/1774 161/18639 0.0745341614906832 0.783112872618289 0.849852276978295 0.964823941849899 GO:0004175 endopeptidase activity 33/1774 405/18639 0.0814814814814815 0.856106726794438 0.850274819051392 0.964823941849899 GO:0008381 mechanosensitive monoatomic ion channel activity 1/1774 19/18639 0.0526315789473684 0.552987598647125 0.850620291590115 0.964823941849899 GO:0015245 fatty acid transmembrane transporter activity 1/1774 19/18639 0.0526315789473684 0.552987598647125 0.850620291590115 0.964823941849899 GO:0016918 retinal binding 1/1774 19/18639 0.0526315789473684 0.552987598647125 0.850620291590115 0.964823941849899 GO:0022821 solute:potassium antiporter activity 1/1774 19/18639 0.0526315789473684 0.552987598647125 0.850620291590115 0.964823941849899 GO:0022840 leak channel activity 1/1774 19/18639 0.0526315789473684 0.552987598647125 0.850620291590115 0.964823941849899 GO:0022842 narrow pore channel activity 1/1774 19/18639 0.0526315789473684 0.552987598647125 0.850620291590115 0.964823941849899 GO:0034987 immunoglobulin receptor binding 1/1774 19/18639 0.0526315789473684 0.552987598647125 0.850620291590115 0.964823941849899 GO:0042800 histone H3K4 methyltransferase activity 1/1774 19/18639 0.0526315789473684 0.552987598647125 0.850620291590115 0.964823941849899 GO:0099589 serotonin receptor activity 1/1774 19/18639 0.0526315789473684 0.552987598647125 0.850620291590115 0.964823941849899 GO:0016651 oxidoreductase activity, acting on NAD(P)H 6/1774 88/18639 0.0681818181818182 0.716370298247412 0.854559221505367 0.968395047496831 GO:0008083 growth factor activity 12/1774 162/18639 0.0740740740740741 0.778278842540398 0.855463916884156 0.968524305159973 GO:0017171 serine hydrolase activity 15/1774 198/18639 0.0757575757575758 0.79596699805268 0.856283496341707 0.96855704803194 GO:0008238 exopeptidase activity 7/1774 102/18639 0.0686274509803922 0.721052457059487 0.863928301264722 0.971076115112106 GO:0001614 purinergic nucleotide receptor activity 1/1774 20/18639 0.05 0.525338218714769 0.864852278846782 0.971076115112106 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/1774 20/18639 0.05 0.525338218714769 0.864852278846782 0.971076115112106 GO:0005326 neurotransmitter transmembrane transporter activity 1/1774 20/18639 0.05 0.525338218714769 0.864852278846782 0.971076115112106 GO:0015095 magnesium ion transmembrane transporter activity 1/1774 20/18639 0.05 0.525338218714769 0.864852278846782 0.971076115112106 GO:0016502 nucleotide receptor activity 1/1774 20/18639 0.05 0.525338218714769 0.864852278846782 0.971076115112106 GO:0016505 peptidase activator activity involved in apoptotic process 1/1774 20/18639 0.05 0.525338218714769 0.864852278846782 0.971076115112106 GO:0043024 ribosomal small subunit binding 1/1774 20/18639 0.05 0.525338218714769 0.864852278846782 0.971076115112106 GO:0048020 CCR chemokine receptor binding 3/1774 50/18639 0.06 0.630405862457723 0.866948468047487 0.972538345566091 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/1774 36/18639 0.0555555555555556 0.583709131905299 0.869531544527476 0.973402119353152 GO:0055106 ubiquitin-protein transferase regulator activity 2/1774 36/18639 0.0555555555555556 0.583709131905299 0.869531544527476 0.973402119353152 GO:0001653 peptide receptor activity 9/1774 128/18639 0.0703125 0.738756870067644 0.87010230260547 0.973402119353152 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 6/1774 91/18639 0.0659340659340659 0.692753695008486 0.875348075254089 0.976912227352343 GO:0003743 translation initiation factor activity 3/1774 51/18639 0.0588235294117647 0.618044963193846 0.875632347455406 0.976912227352343 GO:0005272 sodium channel activity 3/1774 51/18639 0.0588235294117647 0.618044963193846 0.875632347455406 0.976912227352343 GO:0015174 basic amino acid transmembrane transporter activity 1/1774 21/18639 0.0476190476190476 0.500322113061685 0.877729020740858 0.977470954915955 GO:0019200 carbohydrate kinase activity 1/1774 21/18639 0.0476190476190476 0.500322113061685 0.877729020740858 0.977470954915955 GO:0022829 wide pore channel activity 2/1774 37/18639 0.0540540540540541 0.567933209421372 0.879372701132885 0.978411951760022 GO:0008235 metalloexopeptidase activity 4/1774 66/18639 0.0606060606060606 0.636773598442144 0.885008820361686 0.983789296681547 GO:0008970 phospholipase A1 activity 1/1774 22/18639 0.0454545454545455 0.477580198831608 0.889379505068161 0.986856787779435 GO:0061133 endopeptidase activator activity 1/1774 22/18639 0.0454545454545455 0.477580198831608 0.889379505068161 0.986856787779435 GO:0005544 calcium-dependent phospholipid binding 3/1774 53/18639 0.0566037735849057 0.594722511752569 0.891503500727511 0.988318360535023 GO:0008236 serine-type peptidase activity 14/1774 194/18639 0.0721649484536082 0.758220109485233 0.892709159279351 0.988760144771433 GO:0015101 organic cation transmembrane transporter activity 5/1774 81/18639 0.0617283950617284 0.648565702116999 0.894905439093876 0.9902973467841 GO:0051082 unfolded protein binding 8/1774 121/18639 0.0661157024793388 0.69466210739143 0.89957877975306 0.990478481889323 GO:0003887 DNA-directed DNA polymerase activity 1/1774 23/18639 0.0434782608695652 0.456815842360669 0.899920449259442 0.990478481889323 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/1774 23/18639 0.0434782608695652 0.456815842360669 0.899920449259442 0.990478481889323 GO:0005212 structural constituent of eye lens 1/1774 23/18639 0.0434782608695652 0.456815842360669 0.899920449259442 0.990478481889323 GO:0008171 O-methyltransferase activity 1/1774 23/18639 0.0434782608695652 0.456815842360669 0.899920449259442 0.990478481889323 GO:0016493 C-C chemokine receptor activity 1/1774 23/18639 0.0434782608695652 0.456815842360669 0.899920449259442 0.990478481889323 GO:0061135 endopeptidase regulator activity 13/1774 184/18639 0.0706521739130435 0.742325743836086 0.90161134609541 0.991448742340105 GO:0004896 cytokine receptor activity 6/1774 96/18639 0.0625 0.656672773393461 0.904438138611524 0.991529202167886 GO:0015036 disulfide oxidoreductase activity 2/1774 40/18639 0.05 0.525338218714769 0.904922161651998 0.991529202167886 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/1774 40/18639 0.05 0.525338218714769 0.904922161651998 0.991529202167886 GO:0140662 ATP-dependent protein folding chaperone 2/1774 40/18639 0.05 0.525338218714769 0.904922161651998 0.991529202167886 GO:0005254 chloride channel activity 5/1774 83/18639 0.0602409638554217 0.63293761290936 0.906360595171635 0.992217809727661 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/1774 24/18639 0.0416666666666667 0.437781848928974 0.909457467040584 0.993831754794573 GO:0019957 C-C chemokine binding 1/1774 24/18639 0.0416666666666667 0.437781848928974 0.909457467040584 0.993831754794573 GO:0008028 monocarboxylic acid transmembrane transporter activity 4/1774 70/18639 0.0571428571428571 0.600386535674022 0.910421907110524 0.99399896275436 GO:0008227 G protein-coupled amine receptor activity 2/1774 41/18639 0.0487804878048781 0.512525091429043 0.912248496878577 0.994221004160371 GO:0140318 protein transporter activity 2/1774 41/18639 0.0487804878048781 0.512525091429043 0.912248496878577 0.994221004160371 GO:0046943 carboxylic acid transmembrane transporter activity 13/1774 188/18639 0.0691489361702128 0.726531579073617 0.91631846588152 0.995251286015229 GO:0001848 complement binding 1/1774 25/18639 0.04 0.420270574971815 0.918086124224039 0.995251286015229 GO:0005251 delayed rectifier potassium channel activity 1/1774 25/18639 0.04 0.420270574971815 0.918086124224039 0.995251286015229 GO:0015645 fatty acid ligase activity 1/1774 25/18639 0.04 0.420270574971815 0.918086124224039 0.995251286015229 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/1774 25/18639 0.04 0.420270574971815 0.918086124224039 0.995251286015229 GO:0120515 fatty acid-CoA ligase activity 1/1774 25/18639 0.04 0.420270574971815 0.918086124224039 0.995251286015229 GO:0031492 nucleosomal DNA binding 2/1774 42/18639 0.0476190476190476 0.500322113061685 0.91904249297684 0.995251286015229 GO:0005342 organic acid transmembrane transporter activity 13/1774 189/18639 0.0687830687830688 0.722687496644656 0.919693433281012 0.995251286015229 GO:0042379 chemokine receptor binding 4/1774 72/18639 0.0555555555555556 0.583709131905299 0.921149942120725 0.995455691539876 GO:0001637 G protein-coupled chemoattractant receptor activity 1/1774 26/18639 0.0384615384615385 0.404106322088284 0.925892894162072 0.995455691539876 GO:0004950 chemokine receptor activity 1/1774 26/18639 0.0384615384615385 0.404106322088284 0.925892894162072 0.995455691539876 GO:0008157 protein phosphatase 1 binding 1/1774 26/18639 0.0384615384615385 0.404106322088284 0.925892894162072 0.995455691539876 GO:0019865 immunoglobulin binding 1/1774 26/18639 0.0384615384615385 0.404106322088284 0.925892894162072 0.995455691539876 GO:0030247 polysaccharide binding 1/1774 26/18639 0.0384615384615385 0.404106322088284 0.925892894162072 0.995455691539876 GO:0051139 metal cation:proton antiporter activity 1/1774 26/18639 0.0384615384615385 0.404106322088284 0.925892894162072 0.995455691539876 GO:0022804 active transmembrane transporter activity 35/1774 457/18639 0.0765864332603939 0.804675608534657 0.930314790818049 0.995455691539876 GO:0003678 DNA helicase activity 4/1774 74/18639 0.0540540540540541 0.567933209421372 0.930710391602676 0.995455691539876 GO:0003954 NADH dehydrogenase activity 2/1774 44/18639 0.0454545454545455 0.477580198831608 0.931171238407553 0.995455691539876 GO:0030547 signaling receptor inhibitor activity 2/1774 44/18639 0.0454545454545455 0.477580198831608 0.931171238407553 0.995455691539876 GO:0005104 fibroblast growth factor receptor binding 1/1774 27/18639 0.037037037037037 0.389139421270199 0.93295602239269 0.995455691539876 GO:0008320 protein transmembrane transporter activity 1/1774 27/18639 0.037037037037037 0.389139421270199 0.93295602239269 0.995455691539876 GO:0015252 proton channel activity 1/1774 27/18639 0.037037037037037 0.389139421270199 0.93295602239269 0.995455691539876 GO:0016405 CoA-ligase activity 1/1774 27/18639 0.037037037037037 0.389139421270199 0.93295602239269 0.995455691539876 GO:0009055 electron transfer activity 7/1774 116/18639 0.0603448275862069 0.634028884655756 0.933406177500875 0.995455691539876 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 3/1774 60/18639 0.05 0.525338218714769 0.933696807819851 0.995455691539876 GO:0005253 monoatomic anion channel activity 6/1774 103/18639 0.058252427184466 0.612044526657983 0.93522792320469 0.995919004863135 GO:0016798 hydrolase activity, acting on glycosyl bonds 8/1774 130/18639 0.0615384615384615 0.646570115341254 0.935846163083817 0.995919004863135 GO:0008009 chemokine activity 2/1774 45/18639 0.0444444444444444 0.466967305524239 0.936570362124353 0.995919004863135 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 3/1774 61/18639 0.0491803278688525 0.516726116768625 0.93830572393122 0.9968989694846 GO:0004180 carboxypeptidase activity 2/1774 46/18639 0.0434782608695652 0.456815842360669 0.941565965132141 0.999015761452288 GO:0015179 L-amino acid transmembrane transporter activity 3/1774 62/18639 0.0483870967741935 0.50839182456268 0.942616623134131 0.999015761452288 GO:0003724 RNA helicase activity 4/1774 77/18639 0.051948051948052 0.545805941521838 0.943093975496005 0.999015761452288 GO:0035250 UDP-galactosyltransferase activity 1/1774 29/18639 0.0344827586206897 0.362302219803289 0.945127817225731 0.999015761452288 GO:0051861 glycolipid binding 1/1774 29/18639 0.0344827586206897 0.362302219803289 0.945127817225731 0.999015761452288 GO:0140359 ABC-type transporter activity 2/1774 47/18639 0.0425531914893617 0.447096356352995 0.94618589707418 0.999015761452288 GO:0008186 ATP-dependent activity, acting on RNA 4/1774 79/18639 0.0506329113924051 0.531988069584576 0.950189491455962 0.999015761452288 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/1774 30/18639 0.0333333333333333 0.350225479143179 0.95035851320862 0.999015761452288 GO:0048019 receptor antagonist activity 1/1774 30/18639 0.0333333333333333 0.350225479143179 0.95035851320862 0.999015761452288 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/1774 48/18639 0.0416666666666667 0.437781848928974 0.950456365201494 0.999015761452288 GO:0048306 calcium-dependent protein binding 4/1774 80/18639 0.05 0.525338218714769 0.953423882394103 0.999015761452288 GO:0005184 neuropeptide hormone activity 1/1774 31/18639 0.032258064516129 0.338927883041786 0.955090846894896 0.999015761452288 GO:0008327 methyl-CpG binding 1/1774 31/18639 0.032258064516129 0.338927883041786 0.955090846894896 0.999015761452288 GO:0016878 acid-thiol ligase activity 1/1774 31/18639 0.032258064516129 0.338927883041786 0.955090846894896 0.999015761452288 GO:0047499 calcium-independent phospholipase A2 activity 1/1774 31/18639 0.032258064516129 0.338927883041786 0.955090846894896 0.999015761452288 GO:0046906 tetrapyrrole binding 9/1774 152/18639 0.0592105263157895 0.622111048478016 0.959005230706643 0.999015761452288 GO:0008378 galactosyltransferase activity 1/1774 32/18639 0.03125 0.328336386696731 0.959372276259064 0.999015761452288 GO:0022884 macromolecule transmembrane transporter activity 1/1774 32/18639 0.03125 0.328336386696731 0.959372276259064 0.999015761452288 GO:0031369 translation initiation factor binding 1/1774 32/18639 0.03125 0.328336386696731 0.959372276259064 0.999015761452288 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/1774 32/18639 0.03125 0.328336386696731 0.959372276259064 0.999015761452288 GO:0047498 calcium-dependent phospholipase A2 activity 1/1774 32/18639 0.03125 0.328336386696731 0.959372276259064 0.999015761452288 GO:0160041 neuropeptide activity 1/1774 32/18639 0.03125 0.328336386696731 0.959372276259064 0.999015761452288 GO:0005506 iron ion binding 9/1774 154/18639 0.0584415584415584 0.614031684212068 0.963058588321586 0.999015761452288 GO:0019239 deaminase activity 1/1774 33/18639 0.0303030303030303 0.318386799221072 0.963245742261989 0.999015761452288 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 2/1774 52/18639 0.0384615384615385 0.404106322088284 0.964513716746661 0.999015761452288 GO:0020037 heme binding 8/1774 142/18639 0.0563380281690141 0.591930387284247 0.966115934435873 0.999015761452288 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/1774 34/18639 0.0294117647058824 0.309022481596923 0.966750098557121 0.999015761452288 GO:0016251 RNA polymerase II general transcription initiation factor activity 2/1774 53/18639 0.0377358490566038 0.396481674501712 0.967376862472902 0.999015761452288 GO:0003730 mRNA 3'-UTR binding 17/1774 262/18639 0.0648854961832061 0.681736619706189 0.968795853403137 0.999015761452288 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 7/1774 130/18639 0.0538461538461538 0.565748850923597 0.969565112560434 0.999015761452288 GO:0004623 phospholipase A2 activity 1/1774 35/18639 0.0285714285714286 0.300193267837011 0.96992050033942 0.999015761452288 GO:0016229 steroid dehydrogenase activity 1/1774 35/18639 0.0285714285714286 0.300193267837011 0.96992050033942 0.999015761452288 GO:0017069 snRNA binding 2/1774 54/18639 0.037037037037037 0.389139421270199 0.970016845223332 0.999015761452288 GO:0015171 amino acid transmembrane transporter activity 5/1774 102/18639 0.0490196078431373 0.515037469328205 0.971041033312494 0.999015761452288 GO:0004033 aldo-keto reductase (NADPH) activity 1/1774 36/18639 0.0277777777777778 0.291854565952649 0.972788756219761 0.999015761452288 GO:0004190 aspartic-type endopeptidase activity 1/1774 36/18639 0.0277777777777778 0.291854565952649 0.972788756219761 0.999015761452288 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/1774 36/18639 0.0277777777777778 0.291854565952649 0.972788756219761 0.999015761452288 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/1774 36/18639 0.0277777777777778 0.291854565952649 0.972788756219761 0.999015761452288 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/1774 36/18639 0.0277777777777778 0.291854565952649 0.972788756219761 0.999015761452288 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 7/1774 132/18639 0.053030303030303 0.557176898636876 0.972919023193943 0.999015761452288 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 2/1774 56/18639 0.0357142857142857 0.375241584796264 0.974692256801101 0.999435796353463 GO:0070001 aspartic-type peptidase activity 1/1774 37/18639 0.027027027027027 0.283966604710686 0.975383646638841 0.999435796353463 GO:0004252 serine-type endopeptidase activity 10/1774 176/18639 0.0568181818181818 0.59697524853951 0.976280656039475 0.999435796353463 GO:0005501 retinoid binding 1/1774 38/18639 0.0263157894736842 0.276493799323563 0.977731212000775 0.999435796353463 GO:0019840 isoprenoid binding 1/1774 38/18639 0.0263157894736842 0.276493799323563 0.977731212000775 0.999435796353463 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 2/1774 58/18639 0.0344827586206897 0.362302219803289 0.978659002882231 0.999435796353463 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 6/1774 122/18639 0.0491803278688525 0.516726116768625 0.979296127977819 0.999435796353463 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/1774 39/18639 0.0256410256410256 0.269404214725523 0.979855013404497 0.999435796353463 GO:0071855 neuropeptide receptor binding 1/1774 40/18639 0.025 0.262669109357384 0.981776368577638 0.999973874753781 GO:0001530 lipopolysaccharide binding 1/1774 41/18639 0.024390243902439 0.256262545714521 0.983514565370114 0.999973874753781 GO:0008137 NADH dehydrogenase (ubiquinone) activity 1/1774 41/18639 0.024390243902439 0.256262545714521 0.983514565370114 0.999973874753781 GO:0016859 cis-trans isomerase activity 1/1774 42/18639 0.0238095238095238 0.250161056530842 0.985087054940682 0.999973874753781 GO:0042056 chemoattractant activity 1/1774 42/18639 0.0238095238095238 0.250161056530842 0.985087054940682 0.999973874753781 GO:0000049 tRNA binding 3/1774 80/18639 0.0375 0.394003664036077 0.98528038108393 0.999973874753781 GO:0022853 active monoatomic ion transmembrane transporter activity 5/1774 118/18639 0.0423728813559322 0.445201880266753 0.990132271066228 0.999999999732269 GO:0140223 general transcription initiation factor activity 2/1774 68/18639 0.0294117647058824 0.309022481596923 0.991014118732402 0.999999999732269 GO:0015399 primary active transmembrane transporter activity 8/1774 166/18639 0.0481927710843374 0.506350090327488 0.991604468058141 0.999999999732269 GO:0098960 postsynaptic neurotransmitter receptor activity 2/1774 69/18639 0.0289855072463768 0.304543894907112 0.991767153630301 0.999999999732269 GO:0015078 proton transmembrane transporter activity 9/1774 185/18639 0.0486486486486487 0.511139888479235 0.993539374610038 0.999999999732269 GO:0140375 immune receptor activity 7/1774 156/18639 0.0448717948717949 0.471457375769664 0.993849972103078 0.999999999732269 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/1774 53/18639 0.0188679245283019 0.198240837250856 0.99505126709755 0.999999999732269 GO:0030594 neurotransmitter receptor activity 3/1774 97/18639 0.0309278350515464 0.324951475493671 0.996225239248644 0.999999999732269 GO:0022824 transmitter-gated monoatomic ion channel activity 1/1774 63/18639 0.0158730158730159 0.166774037687228 0.998185664888953 0.999999999732269 GO:0022835 transmitter-gated channel activity 1/1774 63/18639 0.0158730158730159 0.166774037687228 0.998185664888953 0.999999999732269 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 1/1774 68/18639 0.0147058823529412 0.154511240798461 0.998901660237698 0.999999999732269 GO:0005125 cytokine activity 10/1774 234/18639 0.0427350427350427 0.449007024542537 0.999213351865325 0.999999999732269 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/1774 73/18639 0.0136986301369863 0.143928279099937 0.999335195172139 0.999999999732269 GO:0005179 hormone activity 3/1774 132/18639 0.0227272727272727 0.238790099415804 0.999802882016663 0.999999999732269 GO:0003735 structural constituent of ribosome 2/1774 175/18639 0.0114285714285714 0.120077307134804 0.999999549863314 0.999999999732269 GO:0003823 antigen binding 1/1774 174/18639 0.00574712643678161 0.0603837033005481 0.999999974592687 0.999999999732269 GO:0045182 translation regulator activity 7/1774 356/18639 0.0196629213483146 0.206593681517044 0.999999998828083 0.999999999732269 GO:0030371 translation repressor activity 5/1774 329/18639 0.0151975683890578 0.15967727012607 0.999999999732269 0.999999999732269