ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003712	transcription coregulator activity	154/2454	495/18639	0.311111111111111	2.36299918500408	5.04671083217281e-26	6.03586615527869e-23
GO:0106310	protein serine kinase activity	103/2454	361/18639	0.285318559556787	2.16709561189036	5.96212439511255e-15	3.5653503882773e-12
GO:0004674	protein serine/threonine kinase activity	116/2454	433/18639	0.267898383371824	2.03478319790849	1.60953176774389e-14	5.65036329313806e-12
GO:0031625	ubiquitin protein ligase binding	90/2454	302/18639	0.298013245033113	2.26351624864392	1.88975360974517e-14	5.65036329313806e-12
GO:0042393	histone binding	78/2454	247/18639	0.315789473684211	2.39853300733496	3.53396231618624e-14	8.45323786031749e-12
GO:0140297	DNA-binding transcription factor binding	125/2454	488/18639	0.256147540983607	1.94553138402341	5.49574579169647e-14	1.0954853278115e-11
GO:0044389	ubiquitin-like protein ligase binding	92/2454	322/18639	0.285714285714286	2.17010129235068	1.55039508743858e-13	2.64896074939506e-11
GO:0003725	double-stranded RNA binding	36/2454	75/18639	0.48	3.64577017114914	2.69357125350604e-13	3.79747330636961e-11
GO:0003714	transcription corepressor activity	67/2454	204/18639	0.32843137254902	2.49455271105997	2.85763041449218e-13	3.79747330636961e-11
GO:0045296	cadherin binding	91/2454	334/18639	0.272455089820359	2.06939299884339	4.0550085510753e-12	4.65420223793762e-10
GO:0140030	modification-dependent protein binding	58/2454	173/18639	0.335260115606936	2.54641943553288	4.28062078740082e-12	4.65420223793762e-10
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	93/2454	349/18639	0.26647564469914	2.02397699329555	9.18746022191659e-12	9.1568353545102e-10
GO:0003713	transcription coactivator activity	74/2454	256/18639	0.2890625	2.19553216687042	2.01189176297749e-11	1.85094042193929e-09
GO:0140857	histone H3T45 kinase activity	71/2454	246/18639	0.288617886178862	2.19215516727294	5.53510816025606e-11	4.12754335979779e-09
GO:0035402	histone H3T11 kinase activity	71/2454	247/18639	0.287449392712551	2.18328004513824	6.78314737510532e-11	4.12754335979779e-09
GO:0035403	histone H3T6 kinase activity	71/2454	247/18639	0.287449392712551	2.18328004513824	6.78314737510532e-11	4.12754335979779e-09
GO:0004679	AMP-activated protein kinase activity	71/2454	248/18639	0.286290322580645	2.17447649656913	8.29910535986521e-11	4.12754335979779e-09
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	70/2454	243/18639	0.288065843621399	2.18796220833711	8.29932033866018e-11	4.12754335979779e-09
GO:0019787	ubiquitin-like protein transferase activity	114/2454	479/18639	0.237995824634656	1.80766266314806	1.08465284445971e-10	4.12754335979779e-09
GO:0004676	3-phosphoinositide-dependent protein kinase activity	70/2454	245/18639	0.285714285714286	2.17010129235068	1.24240435579198e-10	4.12754335979779e-09
GO:0004711	ribosomal protein S6 kinase activity	70/2454	245/18639	0.285714285714286	2.17010129235068	1.24240435579198e-10	4.12754335979779e-09
GO:0035175	histone H3S10 kinase activity	70/2454	245/18639	0.285714285714286	2.17010129235068	1.24240435579198e-10	4.12754335979779e-09
GO:0035979	histone H2AXS139 kinase activity	70/2454	245/18639	0.285714285714286	2.17010129235068	1.24240435579198e-10	4.12754335979779e-09
GO:0044022	histone H3S28 kinase activity	70/2454	245/18639	0.285714285714286	2.17010129235068	1.24240435579198e-10	4.12754335979779e-09
GO:0044023	histone H4S1 kinase activity	70/2454	245/18639	0.285714285714286	2.17010129235068	1.24240435579198e-10	4.12754335979779e-09
GO:0044024	histone H2AS1 kinase activity	70/2454	245/18639	0.285714285714286	2.17010129235068	1.24240435579198e-10	4.12754335979779e-09
GO:0044025	histone H2BS14 kinase activity	70/2454	245/18639	0.285714285714286	2.17010129235068	1.24240435579198e-10	4.12754335979779e-09
GO:0072354	histone H3T3 kinase activity	70/2454	245/18639	0.285714285714286	2.17010129235068	1.24240435579198e-10	4.12754335979779e-09
GO:0072371	histone H2AS121 kinase activity	70/2454	245/18639	0.285714285714286	2.17010129235068	1.24240435579198e-10	4.12754335979779e-09
GO:0072518	Rho-dependent protein serine/threonine kinase activity	70/2454	245/18639	0.285714285714286	2.17010129235068	1.24240435579198e-10	4.12754335979779e-09
GO:0140823	histone H2BS36 kinase activity	70/2454	245/18639	0.285714285714286	2.17010129235068	1.24240435579198e-10	4.12754335979779e-09
GO:0140855	histone H3S57 kinase activity	70/2454	245/18639	0.285714285714286	2.17010129235068	1.24240435579198e-10	4.12754335979779e-09
GO:0140995	histone H2A kinase activity	70/2454	245/18639	0.285714285714286	2.17010129235068	1.24240435579198e-10	4.12754335979779e-09
GO:0140997	histone H4 kinase activity	70/2454	245/18639	0.285714285714286	2.17010129235068	1.24240435579198e-10	4.12754335979779e-09
GO:0140998	histone H2B kinase activity	70/2454	245/18639	0.285714285714286	2.17010129235068	1.24240435579198e-10	4.12754335979779e-09
GO:1990244	histone H2AT120 kinase activity	70/2454	245/18639	0.285714285714286	2.17010129235068	1.24240435579198e-10	4.12754335979779e-09
GO:0004677	DNA-dependent protein kinase activity	70/2454	246/18639	0.284552845528455	2.16127974238178	1.51639610456269e-10	4.90164794880265e-09
GO:0001098	basal transcription machinery binding	28/2454	60/18639	0.466666666666667	3.54449877750611	2.73560898944722e-10	8.38920090097147e-09
GO:0001099	basal RNA polymerase II transcription machinery binding	28/2454	60/18639	0.466666666666667	3.54449877750611	2.73560898944722e-10	8.38920090097147e-09
GO:0019902	phosphatase binding	58/2454	190/18639	0.305263157894737	2.31858190709046	2.93566613318473e-10	8.77764173822233e-09
GO:0140996	histone H3 kinase activity	90/2454	357/18639	0.252100840336134	1.91479525795648	4.66522735272674e-10	1.36088095460029e-08
GO:0141003	histone H2AX kinase activity	89/2454	354/18639	0.251412429378531	1.90956653267581	6.75912812543333e-10	1.92474219952816e-08
GO:0035173	histone kinase activity	90/2454	360/18639	0.25	1.89883863080685	7.38241490415988e-10	2.05334144776168e-08
GO:0004842	ubiquitin-protein transferase activity	106/2454	449/18639	0.236080178173719	1.79311264913609	7.99992594641709e-10	2.17452532543519e-08
GO:0035591	signaling adaptor activity	44/2454	129/18639	0.341085271317829	2.59066355831012	8.65931517784172e-10	2.30145354504416e-08
GO:0016755	aminoacyltransferase activity	114/2454	496/18639	0.229838709677419	1.74570648316113	9.97668967215815e-10	2.59393931476112e-08
GO:0043175	RNA polymerase core enzyme binding	22/2454	42/18639	0.523809523809524	3.97851903597625	1.40134711534285e-09	3.56598117010648e-08
GO:0000993	RNA polymerase II complex binding	20/2454	36/18639	0.555555555555556	4.21964140179299	2.00349458352895e-09	4.99204067062629e-08
GO:0016922	nuclear receptor binding	45/2454	137/18639	0.328467153284672	2.49482447843235	2.20397722323097e-09	5.37950358976375e-08
GO:0061659	ubiquitin-like protein ligase activity	89/2454	372/18639	0.239247311827957	1.81716815206247	9.23853554009244e-09	2.18875411824476e-07
GO:0016887	ATP hydrolysis activity	97/2454	417/18639	0.232613908872902	1.7667851049234	9.33331605606044e-09	2.18875411824476e-07
GO:0043021	ribonucleoprotein complex binding	52/2454	177/18639	0.293785310734463	2.23140358874477	1.03677385194561e-08	2.3845798594749e-07
GO:0031490	chromatin DNA binding	41/2454	128/18639	0.3203125	2.43288699572127	2.53148188013524e-08	5.71255156347499e-07
GO:0070063	RNA polymerase binding	25/2454	59/18639	0.423728813559322	3.21837056068957	2.80560883180145e-08	6.21390400524914e-07
GO:0061630	ubiquitin protein ligase activity	84/2454	353/18639	0.237960339943343	1.80739314433739	3.10720694402614e-08	6.75676273646412e-07
GO:0140296	general transcription initiation factor binding	23/2454	53/18639	0.433962264150943	3.29609724592886	5.85205512896849e-08	1.24983177397256e-06
GO:0019207	kinase regulator activity	71/2454	287/18639	0.247386759581882	1.87899014337681	7.07091044326468e-08	1.4836506824815e-06
GO:0019903	protein phosphatase binding	43/2454	144/18639	0.298611111111111	2.26805725346373	1.1389633846885e-07	2.34862104842663e-06
GO:0019887	protein kinase regulator activity	64/2454	255/18639	0.250980392156863	1.90628505681001	1.75736394425883e-07	3.5623852158196e-06
GO:1990841	promoter-specific chromatin binding	26/2454	68/18639	0.382352941176471	2.904106141234	1.81006899641546e-07	3.60807086618816e-06
GO:0140693	molecular condensate scaffold activity	21/2454	48/18639	0.4375	3.32296760391198	1.85514600603996e-07	3.63730266102262e-06
GO:0002039	p53 binding	26/2454	69/18639	0.376811594202899	2.86201764643351	2.54264308620083e-07	4.90484053402612e-06
GO:0140658	ATP-dependent chromatin remodeler activity	45/2454	158/18639	0.284810126582278	2.16323388319767	2.67613030427964e-07	5.0803997522515e-06
GO:0008094	ATP-dependent activity, acting on DNA	55/2454	210/18639	0.261904761904762	1.98925951798812	2.89760611909016e-07	5.41490143504973e-06
GO:0001221	transcription coregulator binding	36/2454	115/18639	0.31304347826087	2.37767619857553	3.33642593792394e-07	6.13902372578006e-06
GO:0140104	molecular carrier activity	62/2454	249/18639	0.248995983935743	1.8912127728518	3.66702086959346e-07	6.64508630308149e-06
GO:0031072	heat shock protein binding	39/2454	131/18639	0.297709923664122	2.26121241531197	4.74372845064131e-07	8.46790929398061e-06
GO:0019783	ubiquitin-like protein peptidase activity	38/2454	127/18639	0.299212598425197	2.27262576285544	5.75443474736639e-07	1.01210352321326e-05
GO:0032182	ubiquitin-like protein binding	36/2454	120/18639	0.3	2.27860635696821	1.05354305044413e-06	1.82409185078158e-05
GO:0004386	helicase activity	43/2454	155/18639	0.27741935483871	2.10709835160502	1.06761228724675e-06	1.82409185078158e-05
GO:0031491	nucleosome binding	26/2454	74/18639	0.351351351351351	2.66863807572854	1.23043064391719e-06	2.07266908468305e-05
GO:0001222	transcription corepressor binding	20/2454	49/18639	0.408163265306122	3.10014470335812	1.39442470206682e-06	2.31629436621099e-05
GO:0140597	protein carrier chaperone	49/2454	188/18639	0.26063829787234	1.97964027467097	1.46750787910264e-06	2.40430058000926e-05
GO:0019208	phosphatase regulator activity	35/2454	117/18639	0.299145299145299	2.27211460096546	1.59198994846211e-06	2.57299997075768e-05
GO:0061775	cohesin loader activity	42/2454	153/18639	0.274509803921569	2.08499928088595	1.91429314382412e-06	3.05265946668486e-05
GO:0140033	acetylation-dependent protein binding	13/2454	24/18639	0.541666666666667	4.11415036674817	2.09195875000501e-06	3.29208245395525e-05
GO:0045309	protein phosphorylated amino acid binding	22/2454	59/18639	0.372881355932203	2.83216609340682	2.57458566825943e-06	3.99896683017958e-05
GO:0008234	cysteine-type peptidase activity	48/2454	187/18639	0.25668449197861	1.94960971719206	2.9745267112977e-06	4.56094095732314e-05
GO:0043539	protein serine/threonine kinase activator activity	25/2454	73/18639	0.342465753424658	2.60114880932445	3.34897504143323e-06	4.91516778865015e-05
GO:0000510	H3-H4 histone complex chaperone activity	41/2454	151/18639	0.271523178807947	2.06231480432002	3.41102781319367e-06	4.91516778865015e-05
GO:0140584	chromatin extrusion motor activity	41/2454	151/18639	0.271523178807947	2.06231480432002	3.41102781319367e-06	4.91516778865015e-05
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	41/2454	151/18639	0.271523178807947	2.06231480432002	3.41102781319367e-06	4.91516778865015e-05
GO:0140849	ATP-dependent H2AZ histone chaperone activity	41/2454	151/18639	0.271523178807947	2.06231480432002	3.41102781319367e-06	4.91516778865015e-05
GO:0030695	GTPase regulator activity	100/2454	489/18639	0.204498977505112	1.55324223378883	3.66528356668288e-06	5.21866564970563e-05
GO:0017025	TBP-class protein binding	13/2454	25/18639	0.52	3.94958435207824	3.83209201552585e-06	5.39197888302225e-05
GO:0060589	nucleoside-triphosphatase regulator activity	100/2454	490/18639	0.204081632653061	1.55007235167906	4.02116629198976e-06	5.55079198689952e-05
GO:0015616	DNA translocase activity	41/2454	152/18639	0.269736842105263	2.04874694376528	4.08419477296955e-06	5.55079198689952e-05
GO:0140674	ATP-dependent histone chaperone activity	41/2454	152/18639	0.269736842105263	2.04874694376528	4.08419477296955e-06	5.55079198689952e-05
GO:0019888	protein phosphatase regulator activity	32/2454	107/18639	0.299065420560748	2.27150789479697	4.41310833890712e-06	5.93042423969991e-05
GO:0004197	cysteine-type endopeptidase activity	28/2454	88/18639	0.318181818181818	2.41670371193599	4.59801377874521e-06	6.11024942153252e-05
GO:0019209	kinase activator activity	40/2454	148/18639	0.27027027027027	2.05279851979118	5.05147913121191e-06	6.63908685816422e-05
GO:0140713	histone chaperone activity	43/2454	164/18639	0.26219512195122	1.99146490548035	5.3323652016051e-06	6.93207476208663e-05
GO:0004843	cysteine-type deubiquitinase activity	32/2454	108/18639	0.296296296296296	2.25047541428959	5.48777853677555e-06	7.05267824002717e-05
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	36/2454	128/18639	0.28125	2.1361934596577	5.54307487092436e-06	7.05267824002717e-05
GO:0030295	protein kinase activator activity	38/2454	139/18639	0.273381294964029	2.0764278552708	6.43488228900948e-06	8.10117812384772e-05
GO:0051087	protein-folding chaperone binding	37/2454	134/18639	0.276119402985075	2.09722475641353	6.59635466880742e-06	8.15262432626964e-05
GO:0003689	DNA clamp loader activity	42/2454	160/18639	0.2625	1.99378056234719	6.61207825792771e-06	8.15262432626964e-05
GO:0043130	ubiquitin binding	30/2454	100/18639	0.3	2.27860635696821	8.1023983022451e-06	9.88823303008688e-05
GO:0140463	chromatin-protein adaptor activity	20/2454	54/18639	0.37037037037037	2.81309426786199	8.21329515528486e-06	9.92232424820272e-05
GO:0101005	deubiquitinase activity	33/2454	115/18639	0.28695652173913	2.1795365153609	8.41811911138757e-06	0.000100680704572195
GO:0140097	catalytic activity, acting on DNA	73/2454	336/18639	0.217261904761905	1.65018119105833	8.64841615306306e-06	0.000102297236872186
GO:0070577	lysine-acetylated histone binding	12/2454	23/18639	0.521739130434783	3.96279366429255	8.72434628843056e-06	0.000102297236872186
GO:0005085	guanyl-nucleotide exchange factor activity	54/2454	230/18639	0.234782608695652	1.78325714893165	1.2942542494295e-05	0.000150284279836668
GO:0005164	tumor necrosis factor receptor binding	14/2454	31/18639	0.451612903225806	3.43016010726398	1.33074608357249e-05	0.000153035799610836
GO:0051219	phosphoprotein binding	28/2454	93/18639	0.301075268817204	2.28677340484265	1.48874897530723e-05	0.000169575597568328
GO:0003727	single-stranded RNA binding	27/2454	89/18639	0.303370786516854	2.30420867558584	1.80364595453233e-05	0.00020350571336044
GO:0051019	mitogen-activated protein kinase binding	13/2454	28/18639	0.464285714285714	3.52641460006986	1.87686266558006e-05	0.000209787640003155
GO:0051020	GTPase binding	68/2454	315/18639	0.215873015873016	1.63963208755385	2.15497088541584e-05	0.000238643072125681
GO:0008139	nuclear localization sequence binding	12/2454	25/18639	0.48	3.64577017114914	2.59948647296226e-05	0.00028522805703329
GO:0061578	K63-linked deubiquitinase activity	9/2454	15/18639	0.6	4.55721271393643	2.77058062961844e-05	0.00030097930005917
GO:0061980	regulatory RNA binding	20/2454	58/18639	0.344827586206897	2.61908776663013	2.79336975807424e-05	0.00030097930005917
GO:0003925	G protein activity	19/2454	54/18639	0.351851851851852	2.67243955446889	3.19155599900807e-05	0.000340812587036933
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	25/2454	82/18639	0.304878048780488	2.31565686683762	3.31498975594717e-05	0.000349108411799525
GO:0003924	GTPase activity	70/2454	331/18639	0.211480362537764	1.60626832817498	3.32762198538009e-05	0.000349108411799525
GO:0032813	tumor necrosis factor receptor superfamily binding	18/2454	50/18639	0.36	2.73432762836186	3.60139822797511e-05	0.000374545415709411
GO:0035198	miRNA binding	16/2454	42/18639	0.380952380952381	2.89346838980091	4.3583546263361e-05	0.000449361390784308
GO:0032452	histone demethylase activity	13/2454	30/18639	0.433333333333333	3.29132029339853	4.64598200608246e-05	0.000474922605066207
GO:0001784	phosphotyrosine residue binding	17/2454	47/18639	0.361702127659574	2.74725589138012	5.50461546125351e-05	0.000557925431496542
GO:0005521	lamin binding	9/2454	16/18639	0.5625	4.2723869193154	5.59092132417622e-05	0.000561911084345779
GO:0099122	RNA polymerase II C-terminal domain binding	7/2454	10/18639	0.7	5.31674816625917	5.66774597300974e-05	0.000564885348643304
GO:0031267	small GTPase binding	61/2454	283/18639	0.215547703180212	1.6371612223211	5.83959393322789e-05	0.000577202838358724
GO:0044183	protein folding chaperone	23/2454	75/18639	0.306666666666667	2.32924205378973	6.09846052100725e-05	0.000597849080583989
GO:0030159	signaling receptor complex adaptor activity	18/2454	52/18639	0.346153846153846	2.62916118111717	6.55953384899725e-05	0.000637821340113879
GO:0140457	protein demethylase activity	13/2454	31/18639	0.419354838709677	3.18514867103084	7.04031906122858e-05	0.000679050128808821
GO:0033192	calmodulin-dependent protein phosphatase activity	24/2454	81/18639	0.296296296296296	2.25047541428959	7.86193619500704e-05	0.000712339067365789
GO:0140791	histone H2AXS140 phosphatase activity	24/2454	81/18639	0.296296296296296	2.25047541428959	7.86193619500704e-05	0.000712339067365789
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	24/2454	81/18639	0.296296296296296	2.25047541428959	7.86193619500704e-05	0.000712339067365789
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	24/2454	81/18639	0.296296296296296	2.25047541428959	7.86193619500704e-05	0.000712339067365789
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	24/2454	81/18639	0.296296296296296	2.25047541428959	7.86193619500704e-05	0.000712339067365789
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	24/2454	81/18639	0.296296296296296	2.25047541428959	7.86193619500704e-05	0.000712339067365789
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	24/2454	81/18639	0.296296296296296	2.25047541428959	7.86193619500704e-05	0.000712339067365789
GO:1990439	MAP kinase serine/threonine phosphatase activity	24/2454	81/18639	0.296296296296296	2.25047541428959	7.86193619500704e-05	0.000712339067365789
GO:0042288	MHC class I protein binding	10/2454	20/18639	0.5	3.79767726161369	8.04727158387585e-05	0.000723649384535001
GO:0032451	demethylase activity	15/2454	40/18639	0.375	2.84825794621027	9.29439308521287e-05	0.000829559263426462
GO:0033549	MAP kinase phosphatase activity	24/2454	82/18639	0.292682926829268	2.22303059216411	9.74343127323862e-05	0.000863195837243955
GO:0015631	tubulin binding	77/2454	385/18639	0.2	1.51907090464548	9.9722018530286e-05	0.000876967162957515
GO:0046966	nuclear thyroid hormone receptor binding	12/2454	28/18639	0.428571428571429	3.25515193852602	0.00010379261195488	0.000899535970275626
GO:0141052	histone H3 demethylase activity	12/2454	28/18639	0.428571428571429	3.25515193852602	0.00010379261195488	0.000899535970275626
GO:1990226	histone methyltransferase binding	9/2454	17/18639	0.529411764705882	4.02107004170862	0.000104910417941925	0.000902682445025481
GO:0042605	peptide antigen binding	16/2454	45/18639	0.355555555555556	2.70057049714751	0.000114787789621235	0.000980615688478547
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	24/2454	83/18639	0.289156626506024	2.1962470910537	0.000120159671360678	0.0010192267159388
GO:0035613	RNA stem-loop binding	10/2454	21/18639	0.476190476190476	3.61683548725113	0.000135523182134929	0.00113346661421941
GO:0070182	DNA polymerase binding	10/2454	21/18639	0.476190476190476	3.61683548725113	0.000135523182134929	0.00113346661421941
GO:0042608	T cell receptor binding	7/2454	11/18639	0.636363636363636	4.83340742387197	0.000138062453011914	0.00114668537362673
GO:0017018	myosin phosphatase activity	24/2454	84/18639	0.285714285714286	2.17010129235068	0.00014747962003757	0.00121645259010299
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	11/2454	25/18639	0.44	3.34195599022005	0.000151747637198731	0.00124308338417591
GO:0005525	GTP binding	75/2454	378/18639	0.198412698412698	1.50701478635464	0.000158184109222945	0.00128699452129688
GO:0051082	unfolded protein binding	31/2454	121/18639	0.256198347107438	1.94591727454586	0.000164500937203121	0.00132934541145225
GO:0019003	GDP binding	22/2454	75/18639	0.293333333333333	2.2279706601467	0.000180704534139199	0.00145048740154686
GO:0050321	tau-protein kinase activity	10/2454	22/18639	0.454545454545455	3.45243387419427	0.000219215089068002	0.00174787497683553
GO:0140034	methylation-dependent protein binding	22/2454	76/18639	0.289473684210526	2.19865525672372	0.000223089518274825	0.00176698717785888
GO:0043995	histone H4K5 acetyltransferase activity	12/2454	30/18639	0.4	3.03814180929095	0.000228917716290201	0.00177782849794208
GO:0043996	histone H4K8 acetyltransferase activity	12/2454	30/18639	0.4	3.03814180929095	0.000228917716290201	0.00177782849794208
GO:0043997	histone H4K12 acetyltransferase activity	12/2454	30/18639	0.4	3.03814180929095	0.000228917716290201	0.00177782849794208
GO:0050681	nuclear androgen receptor binding	11/2454	26/18639	0.423076923076923	3.21341922136543	0.000231863066157498	0.00178908533628625
GO:0004722	protein serine/threonine phosphatase activity	27/2454	103/18639	0.262135922330097	1.99101526337029	0.000283419559083003	0.00217288328630302
GO:0035259	nuclear glucocorticoid receptor binding	7/2454	12/18639	0.583333333333333	4.43062347188264	0.000293589577117818	0.00223651677855357
GO:0010485	histone H4 acetyltransferase activity	13/2454	35/18639	0.371428571428571	2.82113168005589	0.000302429492674498	0.00227487844804213
GO:0140566	histone reader activity	13/2454	35/18639	0.371428571428571	2.82113168005589	0.000302429492674498	0.00227487844804213
GO:0140789	histone phosphatase activity	33/2454	136/18639	0.242647058823529	1.84299043578312	0.000308678307755263	0.00230737035047059
GO:0001046	core promoter sequence-specific DNA binding	15/2454	44/18639	0.340909090909091	2.5893254056457	0.000317476803035606	0.0023583991082645
GO:0008017	microtubule binding	57/2454	276/18639	0.206521739130435	1.56860582544913	0.000325995492889722	0.00240673215738338
GO:0017124	SH3 domain binding	29/2454	115/18639	0.252173913043478	1.91535027107473	0.000351060235201763	0.00257587755399576
GO:0140662	ATP-dependent protein folding chaperone	14/2454	40/18639	0.35	2.65837408312958	0.000366606216915503	0.00267354289896916
GO:0140142	nucleocytoplasmic carrier activity	12/2454	32/18639	0.375	2.84825794621027	0.000463845002282098	0.00336217347108721
GO:1990782	protein tyrosine kinase binding	29/2454	117/18639	0.247863247863248	1.88260924079995	0.000477800678603573	0.00344246753981852
GO:0140313	molecular sequestering activity	17/2454	55/18639	0.309090909090909	2.3476550344521	0.000486135290168383	0.00348154375473884
GO:0042287	MHC protein binding	14/2454	41/18639	0.341463414634146	2.59353569085813	0.000489889476523191	0.00348754651143891
GO:0036408	histone H3K14 acetyltransferase activity	11/2454	28/18639	0.392857142857143	2.98388927698219	0.000501014779001417	0.00354564305139464
GO:0019001	guanyl nucleotide binding	76/2454	400/18639	0.19	1.4431173594132	0.000562712526119918	0.00393419124279119
GO:0032561	guanyl ribonucleotide binding	76/2454	400/18639	0.19	1.4431173594132	0.000562712526119918	0.00393419124279119
GO:0023023	MHC protein complex binding	13/2454	37/18639	0.351351351351351	2.66863807572854	0.000565786700468298	0.00393419124279119
GO:0030971	receptor tyrosine kinase binding	22/2454	81/18639	0.271604938271605	2.06293579643213	0.000593542342236093	0.00410333318678825
GO:0140311	protein sequestering activity	12/2454	33/18639	0.363636363636364	2.76194709935541	0.000642313398422633	0.00438975328293411
GO:0140416	transcription regulator inhibitor activity	12/2454	33/18639	0.363636363636364	2.76194709935541	0.000642313398422633	0.00438975328293411
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	6/2454	10/18639	0.6	4.55721271393643	0.000676007949863662	0.00459378129566443
GO:0043495	protein-membrane adaptor activity	15/2454	47/18639	0.319148936170213	2.42404931592363	0.000706270645392105	0.00474550388701661
GO:0140938	histone H3 methyltransferase activity	15/2454	47/18639	0.319148936170213	2.42404931592363	0.000706270645392105	0.00474550388701661
GO:0010484	histone H3 acetyltransferase activity	11/2454	29/18639	0.379310344827586	2.88099654329315	0.00071189713640323	0.00475658645328639
GO:0003724	RNA helicase activity	21/2454	77/18639	0.272727272727273	2.07146032451656	0.000737934448245616	0.00490316444500976
GO:0016791	phosphatase activity	55/2454	273/18639	0.201465201465201	1.53019962922163	0.000766834179438309	0.00506703689838794
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	9/2454	21/18639	0.428571428571429	3.25515193852602	0.000772813948302598	0.00507849166027421
GO:0048156	tau protein binding	14/2454	43/18639	0.325581395348837	2.47290612384147	0.000844069883015151	0.00551643486385858
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	15/2454	48/18639	0.3125	2.37354828850856	0.000903801358599672	0.00587470883089787
GO:0035925	mRNA 3'-UTR AU-rich region binding	11/2454	30/18639	0.366666666666667	2.78496332518337	0.000991516800679197	0.00641002212763416
GO:0008186	ATP-dependent activity, acting on RNA	21/2454	79/18639	0.265822784810127	2.01901829098449	0.00106001665281564	0.00677957174741978
GO:0046332	SMAD binding	21/2454	79/18639	0.265822784810127	2.01901829098449	0.00106001665281564	0.00677957174741978
GO:0035064	methylated histone binding	20/2454	74/18639	0.27027027027027	2.05279851979118	0.00110422855621793	0.00702477315551409
GO:0019210	kinase inhibitor activity	23/2454	90/18639	0.255555555555556	1.94103504482478	0.00112970047387334	0.00714879241667997
GO:0070034	telomerase RNA binding	9/2454	22/18639	0.409090909090909	3.10719048677484	0.00115607469700347	0.00725816394617787
GO:0004721	phosphoprotein phosphatase activity	38/2454	175/18639	0.217142857142857	1.64927698218652	0.00115912149976586	0.00725816394617787
GO:0061631	ubiquitin conjugating enzyme activity	12/2454	35/18639	0.342857142857143	2.60412155082082	0.00117355069226665	0.007310242853911
GO:0031593	polyubiquitin modification-dependent protein binding	17/2454	59/18639	0.288135593220339	2.18849198126891	0.00117997235222537	0.00731216027596652
GO:0061791	GTPase motor activity	13/2454	40/18639	0.325	2.4684902200489	0.00130595293770346	0.00800984468458124
GO:1990606	membrane scission GTPase motor activity	13/2454	40/18639	0.325	2.4684902200489	0.00130595293770346	0.00800984468458124
GO:0070990	snRNP binding	6/2454	11/18639	0.545454545454545	4.14292064903312	0.00132154254608576	0.00806410655672738
GO:0004715	non-membrane spanning protein tyrosine kinase activity	14/2454	45/18639	0.311111111111111	2.36299918500408	0.00139284197028558	0.00841929908487134
GO:0042277	peptide binding	50/2454	249/18639	0.200803212851406	1.52517159100951	0.00139383045050546	0.00841929908487134
GO:0016779	nucleotidyltransferase activity	31/2454	136/18639	0.227941176470588	1.73129404573565	0.00140327495093177	0.00843375297142911
GO:0023026	MHC class II protein complex binding	10/2454	27/18639	0.37037037037037	2.81309426786199	0.00153335590544654	0.00916946831457033
GO:0042809	nuclear vitamin D receptor binding	7/2454	15/18639	0.466666666666667	3.54449877750611	0.00166218876221874	0.00987778478155545
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	9/2454	23/18639	0.391304347826087	2.97209524821941	0.00167924492627085	0.00987778478155545
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	9/2454	23/18639	0.391304347826087	2.97209524821941	0.00167924492627085	0.00987778478155545
GO:0061650	ubiquitin-like protein conjugating enzyme activity	13/2454	41/18639	0.317073170731707	2.40828314151112	0.00168483954468003	0.00987778478155545
GO:1990380	K48-linked deubiquitinase activity	8/2454	19/18639	0.421052631578947	3.19804400977995	0.00174710728747782	0.0101928795893828
GO:0030291	protein serine/threonine kinase inhibitor activity	14/2454	46/18639	0.304347826086957	2.31162963750399	0.00176305651615002	0.010235998025803
GO:0005048	signal sequence binding	15/2454	51/18639	0.294117647058824	2.23392780094923	0.00179636763612428	0.0103790130087181
GO:0003697	single-stranded DNA binding	28/2454	121/18639	0.231404958677686	1.75760269958981	0.00183627907177335	0.0105586046626967
GO:0005096	GTPase activator activity	53/2454	271/18639	0.195571955719557	1.48543833849096	0.00188250374416281	0.0107726051579843
GO:0042826	histone deacetylase binding	29/2454	127/18639	0.228346456692913	1.73437229270547	0.00190891592651351	0.0108717307052865
GO:0004402	histone acetyltransferase activity	13/2454	42/18639	0.30952380952381	2.35094306671324	0.00215020012714111	0.0121878642277761
GO:0005078	MAP-kinase scaffold activity	6/2454	12/18639	0.5	3.79767726161369	0.0023494955150537	0.0128898928257075
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	6/2454	12/18639	0.5	3.79767726161369	0.0023494955150537	0.0128898928257075
GO:0070410	co-SMAD binding	6/2454	12/18639	0.5	3.79767726161369	0.0023494955150537	0.0128898928257075
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	6/2454	12/18639	0.5	3.79767726161369	0.0023494955150537	0.0128898928257075
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	6/2454	12/18639	0.5	3.79767726161369	0.0023494955150537	0.0128898928257075
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	6/2454	12/18639	0.5	3.79767726161369	0.0023494955150537	0.0128898928257075
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	6/2454	12/18639	0.5	3.79767726161369	0.0023494955150537	0.0128898928257075
GO:0001091	RNA polymerase II general transcription initiation factor binding	9/2454	24/18639	0.375	2.84825794621027	0.00237608016793431	0.0129172358220429
GO:0043998	histone H2A acetyltransferase activity	9/2454	24/18639	0.375	2.84825794621027	0.00237608016793431	0.0129172358220429
GO:0071889	14-3-3 protein binding	11/2454	33/18639	0.333333333333333	2.53178484107579	0.00241355561406875	0.0130615950879015
GO:0004860	protein kinase inhibitor activity	21/2454	84/18639	0.25	1.89883863080685	0.00243105344859243	0.0130970266870115
GO:0061608	nuclear import signal receptor activity	8/2454	20/18639	0.4	3.03814180929095	0.00257871925630921	0.0138302611235238
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	7/2454	16/18639	0.4375	3.32296760391198	0.00262134531675976	0.0139339066615319
GO:0004708	MAP kinase kinase activity	7/2454	16/18639	0.4375	3.32296760391198	0.00262134531675976	0.0139339066615319
GO:0004712	protein serine/threonine/tyrosine kinase activity	13/2454	43/18639	0.302325581395349	2.29626997213851	0.00271618989959571	0.0143741730969755
GO:0106222	lncRNA binding	10/2454	29/18639	0.344827586206897	2.61908776663013	0.00284107960456023	0.0149688599429693
GO:0030332	cyclin binding	11/2454	34/18639	0.323529411764706	2.45732058104415	0.00314944368020537	0.0165207659716036
GO:0036002	pre-mRNA binding	16/2454	59/18639	0.271186440677966	2.05975715884132	0.00321953911703586	0.0168147108470519
GO:0019211	phosphatase activator activity	9/2454	25/18639	0.36	2.73432762836186	0.00328404357306713	0.017003100057958
GO:0042974	nuclear retinoic acid receptor binding	9/2454	25/18639	0.36	2.73432762836186	0.00328404357306713	0.017003100057958
GO:0001217	DNA-binding transcription repressor activity	53/2454	278/18639	0.190647482014388	1.4480352148599	0.00330490956651042	0.0170373786273554
GO:0017069	snRNA binding	15/2454	54/18639	0.277777777777778	2.1098207008965	0.00332613927728277	0.017073229938327
GO:0140098	catalytic activity, acting on RNA	70/2454	387/18639	0.180878552971576	1.37383673546749	0.00334710802288211	0.0171074410058419
GO:0016763	pentosyltransferase activity	14/2454	49/18639	0.285714285714286	2.17010129235068	0.00339129902699629	0.017221481652774
GO:0001223	transcription coactivator binding	13/2454	44/18639	0.295454545454545	2.24408201822627	0.00339821878767112	0.017221481652774
GO:0120013	lipid transfer activity	17/2454	65/18639	0.261538461538462	1.98647733684408	0.00367457214929803	0.0184656675198271
GO:0009931	calcium-dependent protein serine/threonine kinase activity	8/2454	21/18639	0.380952380952381	2.89346838980091	0.00369004559969789	0.0184656675198271
GO:0051010	microtubule plus-end binding	8/2454	21/18639	0.380952380952381	2.89346838980091	0.00369004559969789	0.0184656675198271
GO:0008187	poly-pyrimidine tract binding	10/2454	30/18639	0.333333333333333	2.53178484107579	0.00376586100650075	0.018688671218983
GO:0051721	protein phosphatase 2A binding	10/2454	30/18639	0.333333333333333	2.53178484107579	0.00376586100650075	0.018688671218983
GO:0042578	phosphoric ester hydrolase activity	66/2454	363/18639	0.181818181818182	1.38097354967771	0.00379177822615955	0.0187395320598629
GO:0004535	poly(A)-specific ribonuclease activity	6/2454	13/18639	0.461538461538462	3.50554824148956	0.00388010785980048	0.0187878906895602
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	6/2454	13/18639	0.461538461538462	3.50554824148956	0.00388010785980048	0.0187878906895602
GO:0043560	insulin receptor substrate binding	6/2454	13/18639	0.461538461538462	3.50554824148956	0.00388010785980048	0.0187878906895602
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	6/2454	13/18639	0.461538461538462	3.50554824148956	0.00388010785980048	0.0187878906895602
GO:0140852	histone ubiquitin ligase activity	6/2454	13/18639	0.461538461538462	3.50554824148956	0.00388010785980048	0.0187878906895602
GO:0032183	SUMO binding	7/2454	17/18639	0.411764705882353	3.12749892132892	0.00395434785566373	0.019070161432959
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	51/2454	268/18639	0.190298507462687	1.44538462942014	0.00404664028249801	0.0194368746099101
GO:0004532	RNA exonuclease activity	12/2454	40/18639	0.3	2.27860635696821	0.0041916662887096	0.0200529315251867
GO:0032931	histone H3K56 acetyltransferase activity	8/2454	22/18639	0.363636363636364	2.76194709935541	0.00513802897266612	0.0233653332749379
GO:0043992	histone H3K9 acetyltransferase activity	8/2454	22/18639	0.363636363636364	2.76194709935541	0.00513802897266612	0.0233653332749379
GO:0043993	histone H3K18 acetyltransferase activity	8/2454	22/18639	0.363636363636364	2.76194709935541	0.00513802897266612	0.0233653332749379
GO:0043994	histone H3K23 acetyltransferase activity	8/2454	22/18639	0.363636363636364	2.76194709935541	0.00513802897266612	0.0233653332749379
GO:0043999	histone H2AK5 acetyltransferase activity	8/2454	22/18639	0.363636363636364	2.76194709935541	0.00513802897266612	0.0233653332749379
GO:0044012	histone H2AK9 acetyltransferase activity	8/2454	22/18639	0.363636363636364	2.76194709935541	0.00513802897266612	0.0233653332749379
GO:0044014	histone H2BK5 acetyltransferase activity	8/2454	22/18639	0.363636363636364	2.76194709935541	0.00513802897266612	0.0233653332749379
GO:0044015	histone H2BK12 acetyltransferase activity	8/2454	22/18639	0.363636363636364	2.76194709935541	0.00513802897266612	0.0233653332749379
GO:0044016	histone H3K4 acetyltransferase activity	8/2454	22/18639	0.363636363636364	2.76194709935541	0.00513802897266612	0.0233653332749379
GO:0044017	histone H3K27 acetyltransferase activity	8/2454	22/18639	0.363636363636364	2.76194709935541	0.00513802897266612	0.0233653332749379
GO:0044018	histone H3K36 acetyltransferase activity	8/2454	22/18639	0.363636363636364	2.76194709935541	0.00513802897266612	0.0233653332749379
GO:0046972	histone H4K16 acetyltransferase activity	8/2454	22/18639	0.363636363636364	2.76194709935541	0.00513802897266612	0.0233653332749379
GO:0140908	histone H3K122 acetyltransferase activity	8/2454	22/18639	0.363636363636364	2.76194709935541	0.00513802897266612	0.0233653332749379
GO:0051015	actin filament binding	41/2454	209/18639	0.196172248803828	1.48999777728384	0.00543562043880463	0.0246250077454937
GO:0044325	transmembrane transporter binding	29/2454	136/18639	0.213235294117647	1.61959765568819	0.00546596565063535	0.0246545756681108
GO:0030957	Tat protein binding	5/2454	10/18639	0.5	3.79767726161369	0.00558644649335956	0.0246545756681108
GO:0031996	thioesterase binding	5/2454	10/18639	0.5	3.79767726161369	0.00558644649335956	0.0246545756681108
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	5/2454	10/18639	0.5	3.79767726161369	0.00558644649335956	0.0246545756681108
GO:0045322	unmethylated CpG binding	5/2454	10/18639	0.5	3.79767726161369	0.00558644649335956	0.0246545756681108
GO:0051864	histone H3K36 demethylase activity	5/2454	10/18639	0.5	3.79767726161369	0.00558644649335956	0.0246545756681108
GO:0070513	death domain binding	5/2454	10/18639	0.5	3.79767726161369	0.00558644649335956	0.0246545756681108
GO:0032934	sterol binding	17/2454	68/18639	0.25	1.89883863080685	0.00602402157198343	0.0263663714207302
GO:0044548	S100 protein binding	6/2454	14/18639	0.428571428571429	3.25515193852602	0.0060404563288295	0.0263663714207302
GO:0046030	inositol trisphosphate phosphatase activity	6/2454	14/18639	0.428571428571429	3.25515193852602	0.0060404563288295	0.0263663714207302
GO:0061733	protein-lysine-acetyltransferase activity	13/2454	47/18639	0.276595744680851	2.10084274046715	0.00631228408163183	0.0272798701118448
GO:1990518	single-stranded 3'-5' DNA helicase activity	13/2454	47/18639	0.276595744680851	2.10084274046715	0.00631228408163183	0.0272798701118448
GO:0051059	NF-kappaB binding	10/2454	32/18639	0.3125	2.37354828850856	0.00631816389714132	0.0272798701118448
GO:0051879	Hsp90 protein binding	12/2454	42/18639	0.285714285714286	2.17010129235068	0.00646048341884379	0.0277940221904215
GO:0044013	histone H2B acetyltransferase activity	8/2454	23/18639	0.347826086956522	2.6418624428617	0.00698271379741027	0.0299330670311924
GO:0043138	3'-5' DNA helicase activity	13/2454	48/18639	0.270833333333333	2.05707518337408	0.00763548921091445	0.0326144467723346
GO:0019789	SUMO transferase activity	9/2454	28/18639	0.321428571428571	2.44136395389452	0.00769551353449833	0.0326377098839007
GO:0097718	disordered domain specific binding	9/2454	28/18639	0.321428571428571	2.44136395389452	0.00769551353449833	0.0326377098839007
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	11/2454	38/18639	0.289473684210526	2.19865525672372	0.00805808967187715	0.0340546828535868
GO:0003779	actin binding	76/2454	443/18639	0.171557562076749	1.3030405051135	0.00889025746147649	0.0374392532532602
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	6/2454	15/18639	0.4	3.03814180929095	0.00895930137323665	0.0374661693789896
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	6/2454	15/18639	0.4	3.03814180929095	0.00895930137323665	0.0374661693789896
GO:0060590	ATPase regulator activity	13/2454	49/18639	0.26530612244898	2.01509405718278	0.00916811344399602	0.0382057967910078
GO:0050699	WW domain binding	8/2454	24/18639	0.333333333333333	2.53178484107579	0.00928603061214827	0.0385628215698935
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	15/2454	60/18639	0.25	1.89883863080685	0.00954945474367192	0.0395195428146423
GO:0043022	ribosome binding	24/2454	112/18639	0.214285714285714	1.62757596926301	0.0101597918127062	0.0419003827861951
GO:0043024	ribosomal small subunit binding	7/2454	20/18639	0.35	2.65837408312958	0.0110347001257632	0.0451969224329206
GO:0052745	inositol phosphate phosphatase activity	7/2454	20/18639	0.35	2.65837408312958	0.0110347001257632	0.0451969224329206
GO:0042054	histone methyltransferase activity	16/2454	67/18639	0.238805970149254	1.81381600554684	0.011913034507655	0.0486279497309056
GO:0004709	MAP kinase kinase kinase activity	8/2454	25/18639	0.32	2.43051344743276	0.0121104951011276	0.0490988208167751
GO:0017056	structural constituent of nuclear pore	8/2454	25/18639	0.32	2.43051344743276	0.0121104951011276	0.0490988208167751
GO:0140328	floppase activity	6/2454	16/18639	0.375	2.84825794621027	0.0127620750071228	0.0515656814476989
GO:0030544	Hsp70 protein binding	13/2454	51/18639	0.254901960784314	1.93607076082267	0.0129466184475753	0.0521352042535355
GO:0005095	GTPase inhibitor activity	5/2454	12/18639	0.416666666666667	3.16473105134474	0.0139912742596835	0.0559650970387338
GO:0035197	siRNA binding	5/2454	12/18639	0.416666666666667	3.16473105134474	0.0139912742596835	0.0559650970387338
GO:0016504	peptidase activator activity	14/2454	57/18639	0.245614035087719	1.86552567237164	0.014089446426127	0.0561699264188261
GO:0003678	DNA helicase activity	17/2454	74/18639	0.22972972972973	1.74487874182251	0.0143181677151112	0.0568921215524018
GO:0001727	lipid kinase activity	11/2454	41/18639	0.268292682926829	2.0377780428171	0.0146041740307912	0.0576455186165885
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	11/2454	41/18639	0.268292682926829	2.0377780428171	0.0146041740307912	0.0576455186165885
GO:0072542	protein phosphatase activator activity	7/2454	21/18639	0.333333333333333	2.53178484107579	0.0147070273887959	0.0578605419638153
GO:0052742	phosphatidylinositol kinase activity	8/2454	26/18639	0.307692307692308	2.33703216099304	0.015517872303608	0.0608504107380826
GO:0061749	forked DNA-dependent helicase activity	12/2454	47/18639	0.25531914893617	1.93923945273891	0.0163864158439671	0.0640462527757668
GO:0000287	magnesium ion binding	42/2454	230/18639	0.182608695652174	1.38697778250239	0.0167985097353754	0.0654430542133842
GO:0051787	misfolded protein binding	6/2454	17/18639	0.352941176470588	2.68071336113908	0.0175662898170095	0.068211956562154
GO:0016251	RNA polymerase II general transcription initiation factor activity	13/2454	53/18639	0.245283018867925	1.86301148682936	0.0178212471091307	0.0687555211049044
GO:0034212	protein N-acetyltransferase activity	13/2454	53/18639	0.245283018867925	1.86301148682936	0.0178212471091307	0.0687555211049044
GO:0097110	scaffold protein binding	16/2454	70/18639	0.228571428571429	1.73608103388054	0.0179865046683439	0.0691699665059143
GO:0070717	poly-purine tract binding	9/2454	32/18639	0.28125	2.1361934596577	0.019237706232543	0.0732916066680262
GO:0120015	sterol transfer activity	9/2454	32/18639	0.28125	2.1361934596577	0.019237706232543	0.0732916066680262
GO:0009378	four-way junction helicase activity	12/2454	48/18639	0.25	1.89883863080685	0.0193033913883179	0.0732916066680262
GO:0036121	double-stranded DNA helicase activity	12/2454	48/18639	0.25	1.89883863080685	0.0193033913883179	0.0732916066680262
GO:0001671	ATPase activator activity	8/2454	27/18639	0.296296296296296	2.25047541428959	0.0195678536354022	0.0738269809083312
GO:0008266	poly(U) RNA binding	8/2454	27/18639	0.296296296296296	2.25047541428959	0.0195678536354022	0.0738269809083312
GO:0005035	death receptor activity	5/2454	13/18639	0.384615384615385	2.9212902012413	0.0203107532596103	0.0756749560700744
GO:0046975	histone H3K36 methyltransferase activity	5/2454	13/18639	0.384615384615385	2.9212902012413	0.0203107532596103	0.0756749560700744
GO:0097157	pre-mRNA intronic binding	5/2454	13/18639	0.384615384615385	2.9212902012413	0.0203107532596103	0.0756749560700744
GO:0140666	annealing activity	5/2454	13/18639	0.384615384615385	2.9212902012413	0.0203107532596103	0.0756749560700744
GO:0005516	calmodulin binding	38/2454	207/18639	0.183574879227053	1.39431628928812	0.0204178071757614	0.075837569509971
GO:0043531	ADP binding	10/2454	38/18639	0.263157894736842	1.99877750611247	0.0222071334407588	0.0822282711924074
GO:0000900	mRNA regulatory element binding translation repressor activity	6/2454	18/18639	0.333333333333333	2.53178484107579	0.0234775654394671	0.0863974408172389
GO:0004706	JUN kinase kinase kinase activity	6/2454	18/18639	0.333333333333333	2.53178484107579	0.0234775654394671	0.0863974408172389
GO:0005158	insulin receptor binding	7/2454	23/18639	0.304347826086957	2.31162963750399	0.0245056176891807	0.0896715895875814
GO:0043014	alpha-tubulin binding	11/2454	44/18639	0.25	1.89883863080685	0.0245172322701832	0.0896715895875814
GO:0004713	protein tyrosine kinase activity	27/2454	140/18639	0.192857142857143	1.46481837233671	0.0257531258130693	0.0939046904647281
GO:0003774	cytoskeletal motor activity	29/2454	153/18639	0.189542483660131	1.43964236061173	0.0265706187342256	0.096591063848431
GO:1990825	sequence-specific mRNA binding	5/2454	14/18639	0.357142857142857	2.71262661543835	0.028238695998933	0.102150653186386
GO:0015035	protein-disulfide reductase activity	9/2454	34/18639	0.264705882352941	2.01053502085431	0.0282707911410482	0.102150653186386
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	8/2454	29/18639	0.275862068965517	2.09527021330411	0.029816515722542	0.10708874715964
GO:0097472	cyclin-dependent protein kinase activity	8/2454	29/18639	0.275862068965517	2.09527021330411	0.029816515722542	0.10708874715964
GO:0042800	histone H3K4 methyltransferase activity	6/2454	19/18639	0.315789473684211	2.39853300733496	0.0305863924939345	0.108887330641374
GO:0140036	ubiquitin-modified protein reader activity	6/2454	19/18639	0.315789473684211	2.39853300733496	0.0305863924939345	0.108887330641374
GO:0005315	phosphate transmembrane transporter activity	7/2454	24/18639	0.291666666666667	2.21531173594132	0.0307725064856058	0.108887330641374
GO:0035035	histone acetyltransferase binding	7/2454	24/18639	0.291666666666667	2.21531173594132	0.0307725064856058	0.108887330641374
GO:0048027	mRNA 5'-UTR binding	7/2454	24/18639	0.291666666666667	2.21531173594132	0.0307725064856058	0.108887330641374
GO:0015036	disulfide oxidoreductase activity	10/2454	40/18639	0.25	1.89883863080685	0.0312304557960999	0.109857720976869
GO:0050997	quaternary ammonium group binding	10/2454	40/18639	0.25	1.89883863080685	0.0312304557960999	0.109857720976869
GO:0004445	inositol-polyphosphate 5-phosphatase activity	4/2454	10/18639	0.4	3.03814180929095	0.0326105606545037	0.113049943602279
GO:0005031	tumor necrosis factor receptor activity	4/2454	10/18639	0.4	3.03814180929095	0.0326105606545037	0.113049943602279
GO:0042975	peroxisome proliferator activated receptor binding	4/2454	10/18639	0.4	3.03814180929095	0.0326105606545037	0.113049943602279
GO:0050815	phosphoserine residue binding	4/2454	10/18639	0.4	3.03814180929095	0.0326105606545037	0.113049943602279
GO:0140999	histone H3K4 trimethyltransferase activity	4/2454	10/18639	0.4	3.03814180929095	0.0326105606545037	0.113049943602279
GO:0008080	N-acetyltransferase activity	15/2454	69/18639	0.217391304347826	1.65116402678856	0.0328135005049666	0.113097828829798
GO:0016279	protein-lysine N-methyltransferase activity	15/2454	69/18639	0.217391304347826	1.65116402678856	0.0328135005049666	0.113097828829798
GO:0000175	3'-5'-RNA exonuclease activity	9/2454	35/18639	0.257142857142857	1.95309116311561	0.0337510811070937	0.115332265725955
GO:0005154	epidermal growth factor receptor binding	9/2454	35/18639	0.257142857142857	1.95309116311561	0.0337510811070937	0.115332265725955
GO:0043015	gamma-tubulin binding	9/2454	35/18639	0.257142857142857	1.95309116311561	0.0337510811070937	0.115332265725955
GO:0017116	single-stranded DNA helicase activity	13/2454	58/18639	0.224137931034483	1.70240704830959	0.0359333505912918	0.122355544699165
GO:0015215	nucleotide transmembrane transporter activity	8/2454	30/18639	0.266666666666667	2.02542787286064	0.036113300400339	0.122355544699165
GO:0031210	phosphatidylcholine binding	8/2454	30/18639	0.266666666666667	2.02542787286064	0.036113300400339	0.122355544699165
GO:0042169	SH2 domain binding	10/2454	41/18639	0.24390243902439	1.85252549347009	0.0365937724945865	0.123633197467586
GO:0140272	exogenous protein binding	17/2454	82/18639	0.207317073170732	1.57464666944958	0.0367601307463535	0.123649654068496
GO:0016278	lysine N-methyltransferase activity	15/2454	70/18639	0.214285714285714	1.62757596926301	0.0368572266422272	0.123649654068496
GO:0017022	myosin binding	16/2454	76/18639	0.210526315789474	1.59902200488998	0.0369088014234558	0.123649654068496
GO:0016004	phospholipase activator activity	6/2454	20/18639	0.3	2.27860635696821	0.0389656892231507	0.130175877963375
GO:0008135	translation factor activity, RNA binding	17/2454	83/18639	0.204819277108434	1.55567502282971	0.0407633829670143	0.135802245204872
GO:0019894	kinesin binding	10/2454	42/18639	0.238095238095238	1.80841774362557	0.0425624918055364	0.141010360663218
GO:0048487	beta-tubulin binding	10/2454	42/18639	0.238095238095238	1.80841774362557	0.0425624918055364	0.141010360663218
GO:0035401	histone H3Y41 kinase activity	22/2454	115/18639	0.191304347826087	1.45302434357393	0.0443688802154743	0.146185070902775
GO:0140801	histone H2AXY142 kinase activity	22/2454	115/18639	0.191304347826087	1.45302434357393	0.0443688802154743	0.146185070902775
GO:0180051	translation factor activity	17/2454	84/18639	0.202380952380952	1.53715508208173	0.0450713262248742	0.148091500453158
GO:0015485	cholesterol binding	12/2454	54/18639	0.222222222222222	1.6878565607172	0.0453996348652772	0.148761543284579
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	13/2454	60/18639	0.216666666666667	1.64566014669927	0.0459655560678525	0.148763021445284
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	4/2454	11/18639	0.363636363636364	2.76194709935541	0.0460220049621699	0.148763021445284
GO:0043522	leucine zipper domain binding	4/2454	11/18639	0.363636363636364	2.76194709935541	0.0460220049621699	0.148763021445284
GO:0140031	phosphorylation-dependent protein binding	4/2454	11/18639	0.363636363636364	2.76194709935541	0.0460220049621699	0.148763021445284
GO:0140537	transcription regulator activator activity	4/2454	11/18639	0.363636363636364	2.76194709935541	0.0460220049621699	0.148763021445284
GO:0043548	phosphatidylinositol 3-kinase binding	7/2454	26/18639	0.269230769230769	2.04490314086891	0.0463238806929356	0.148933766959008
GO:0070412	R-SMAD binding	7/2454	26/18639	0.269230769230769	2.04490314086891	0.0463238806929356	0.148933766959008
GO:0046982	protein heterodimerization activity	60/2454	369/18639	0.16260162601626	1.23501699564673	0.0477440709454578	0.15308822748195
GO:0005159	insulin-like growth factor receptor binding	5/2454	16/18639	0.3125	2.37354828850856	0.0492949016320804	0.155970112042244
GO:0008142	oxysterol binding	5/2454	16/18639	0.3125	2.37354828850856	0.0492949016320804	0.155970112042244
GO:0015562	efflux transmembrane transporter activity	5/2454	16/18639	0.3125	2.37354828850856	0.0492949016320804	0.155970112042244
GO:0030275	LRR domain binding	5/2454	16/18639	0.3125	2.37354828850856	0.0492949016320804	0.155970112042244
GO:0034450	ubiquitin-ubiquitin ligase activity	5/2454	16/18639	0.3125	2.37354828850856	0.0492949016320804	0.155970112042244
GO:0035254	glutamate receptor binding	11/2454	49/18639	0.224489795918367	1.70507958684696	0.0506075932039988	0.159701006522381
GO:0004725	protein tyrosine phosphatase activity	19/2454	98/18639	0.193877551020408	1.47256873409511	0.0522102368834569	0.16432485082267
GO:0042162	telomeric DNA binding	9/2454	38/18639	0.236842105263158	1.79889975550122	0.0544483153283297	0.170919121083156
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	7/2454	27/18639	0.259259259259259	1.9691659875034	0.0556884901630723	0.174354539882289
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	76/2454	484/18639	0.15702479338843	1.19265897472166	0.0568658999188107	0.177576021678584
GO:0140223	general transcription initiation factor activity	14/2454	68/18639	0.205882352941176	1.56374946066446	0.0573446224477751	0.178604605332133
GO:0061133	endopeptidase activator activity	6/2454	22/18639	0.272727272727273	2.07146032451656	0.0597303766971064	0.185071322615905
GO:0140035	ubiquitin-like protein reader activity	6/2454	22/18639	0.272727272727273	2.07146032451656	0.0597303766971064	0.185071322615905
GO:0019956	chemokine binding	8/2454	33/18639	0.242424242424242	1.84129806623694	0.060147332255896	0.185881677979461
GO:0001618	virus receptor activity	16/2454	81/18639	0.197530864197531	1.50031694285973	0.0612855874195608	0.188808402120737
GO:0005319	lipid transporter activity	31/2454	178/18639	0.174157303370787	1.32278646191039	0.0617748488036433	0.188808402120737
GO:0005049	nuclear export signal receptor activity	4/2454	12/18639	0.333333333333333	2.53178484107579	0.0620373703134132	0.188808402120737
GO:1990247	N6-methyladenosine-containing RNA reader activity	4/2454	12/18639	0.333333333333333	2.53178484107579	0.0620373703134132	0.188808402120737
GO:1990817	poly(A) RNA polymerase activity	4/2454	12/18639	0.333333333333333	2.53178484107579	0.0620373703134132	0.188808402120737
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	5/2454	17/18639	0.294117647058824	2.23392780094923	0.0625151565550266	0.188808402120737
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	5/2454	17/18639	0.294117647058824	2.23392780094923	0.0625151565550266	0.188808402120737
GO:0046965	nuclear retinoid X receptor binding	5/2454	17/18639	0.294117647058824	2.23392780094923	0.0625151565550266	0.188808402120737
GO:0070403	NAD+ binding	5/2454	17/18639	0.294117647058824	2.23392780094923	0.0625151565550266	0.188808402120737
GO:0046875	ephrin receptor binding	7/2454	28/18639	0.25	1.89883863080685	0.0661457236588417	0.199270240544017
GO:0052866	phosphatidylinositol phosphate phosphatase activity	8/2454	34/18639	0.235294117647059	1.78714224075938	0.0699554987527723	0.210218031427929
GO:0005496	steroid binding	20/2454	108/18639	0.185185185185185	1.406547133931	0.0705696928898019	0.211322279651025
GO:0005543	phospholipid binding	77/2454	497/18639	0.154929577464789	1.17674506697889	0.070676347709373	0.211322279651025
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	29/2454	167/18639	0.173652694610778	1.3189537794826	0.0710146809888465	0.211804385193667
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	17/2454	89/18639	0.191011235955056	1.45079805499849	0.071503824953888	0.212204899863152
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	17/2454	89/18639	0.191011235955056	1.45079805499849	0.071503824953888	0.212204899863152
GO:0030276	clathrin binding	10/2454	46/18639	0.217391304347826	1.65116402678856	0.0729155893650934	0.215859021981811
GO:0001216	DNA-binding transcription activator activity	76/2454	491/18639	0.154786150712831	1.17565568994966	0.0732644999159197	0.216356399751704
GO:0016407	acetyltransferase activity	18/2454	96/18639	0.1875	1.42412897310513	0.0753840615590994	0.222067334050943
GO:0008525	phosphatidylcholine transporter activity	5/2454	18/18639	0.277777777777778	2.1098207008965	0.0775296146763957	0.226712516266428
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	5/2454	18/18639	0.277777777777778	2.1098207008965	0.0775296146763957	0.226712516266428
GO:0070628	proteasome binding	5/2454	18/18639	0.277777777777778	2.1098207008965	0.0775296146763957	0.226712516266428
GO:0140793	histone H2AXY142 phosphatase activity	17/2454	90/18639	0.188888888888889	1.43467807660962	0.0778212032183751	0.227010144022382
GO:0004527	exonuclease activity	16/2454	84/18639	0.19047619047619	1.44673419490045	0.0802531053599881	0.231674783664255
GO:0004879	nuclear receptor activity	12/2454	59/18639	0.203389830508475	1.54481786913099	0.0805480687204459	0.231674783664255
GO:0019855	calcium channel inhibitor activity	4/2454	13/18639	0.307692307692308	2.33703216099304	0.0805825334484367	0.231674783664255
GO:0046974	histone H3K9 methyltransferase activity	4/2454	13/18639	0.307692307692308	2.33703216099304	0.0805825334484367	0.231674783664255
GO:0140333	glycerophospholipid flippase activity	4/2454	13/18639	0.307692307692308	2.33703216099304	0.0805825334484367	0.231674783664255
GO:0140410	monoatomic cation:bicarbonate symporter activity	4/2454	13/18639	0.307692307692308	2.33703216099304	0.0805825334484367	0.231674783664255
GO:0005246	calcium channel regulator activity	11/2454	53/18639	0.207547169811321	1.57639433500946	0.0816332374059907	0.234132738459388
GO:0060229	lipase activator activity	6/2454	24/18639	0.25	1.89883863080685	0.0859593572811402	0.24536370240631
GO:0070300	phosphatidic acid binding	6/2454	24/18639	0.25	1.89883863080685	0.0859593572811402	0.24536370240631
GO:0008170	N-methyltransferase activity	18/2454	98/18639	0.183673469387755	1.39506511651115	0.0883103765820408	0.251474310457431
GO:0098531	ligand-modulated transcription factor activity	12/2454	60/18639	0.2	1.51907090464548	0.089193696883594	0.25338636929401
GO:1901981	phosphatidylinositol phosphate binding	31/2454	185/18639	0.167567567567568	1.27273508227053	0.0926369429548455	0.262241931306624
GO:0031492	nucleosomal DNA binding	9/2454	42/18639	0.214285714285714	1.62757596926301	0.092749445604266	0.262241931306624
GO:0031420	alkali metal ion binding	5/2454	19/18639	0.263157894736842	1.99877750611247	0.0942950511701318	0.265983210376127
GO:0051213	dioxygenase activity	17/2454	93/18639	0.182795698924731	1.38839813865447	0.0989244114777709	0.278384932064503
GO:0015662	P-type ion transporter activity	6/2454	25/18639	0.24	1.82288508557457	0.101094957888654	0.279764981198555
GO:0120020	cholesterol transfer activity	6/2454	25/18639	0.24	1.82288508557457	0.101094957888654	0.279764981198555
GO:0140358	P-type transmembrane transporter activity	6/2454	25/18639	0.24	1.82288508557457	0.101094957888654	0.279764981198555
GO:0003684	damaged DNA binding	14/2454	74/18639	0.189189189189189	1.43695896385383	0.101504869943655	0.279764981198555
GO:0004705	JUN kinase activity	4/2454	14/18639	0.285714285714286	2.17010129235068	0.101520068428238	0.279764981198555
GO:0008174	mRNA methyltransferase activity	4/2454	14/18639	0.285714285714286	2.17010129235068	0.101520068428238	0.279764981198555
GO:0032036	myosin heavy chain binding	4/2454	14/18639	0.285714285714286	2.17010129235068	0.101520068428238	0.279764981198555
GO:0032454	histone H3K9 demethylase activity	4/2454	14/18639	0.285714285714286	2.17010129235068	0.101520068428238	0.279764981198555
GO:0042043	neurexin family protein binding	4/2454	14/18639	0.285714285714286	2.17010129235068	0.101520068428238	0.279764981198555
GO:0035091	phosphatidylinositol binding	45/2454	284/18639	0.158450704225352	1.20348927304659	0.106256894300011	0.292145392144398
GO:0016410	N-acyltransferase activity	17/2454	94/18639	0.180851063829787	1.37362794569006	0.106683108909142	0.292644491411317
GO:0015605	organophosphate ester transmembrane transporter activity	10/2454	50/18639	0.2	1.51907090464548	0.114152340098339	0.312416930795453
GO:0008276	protein methyltransferase activity	17/2454	95/18639	0.178947368421053	1.35916870415648	0.114804620155595	0.313484761886055
GO:0005112	Notch binding	6/2454	26/18639	0.230769230769231	1.75277412074478	0.117526281047369	0.318012289892882
GO:0005160	transforming growth factor beta receptor binding	6/2454	26/18639	0.230769230769231	1.75277412074478	0.117526281047369	0.318012289892882
GO:0008143	poly(A) binding	6/2454	26/18639	0.230769230769231	1.75277412074478	0.117526281047369	0.318012289892882
GO:0015216	purine nucleotide transmembrane transporter activity	6/2454	26/18639	0.230769230769231	1.75277412074478	0.117526281047369	0.318012289892882
GO:0030515	snoRNA binding	7/2454	32/18639	0.21875	1.66148380195599	0.118905234843639	0.321017293167026
GO:0008168	methyltransferase activity	33/2454	204/18639	0.161764705882353	1.22866029052208	0.121611559543831	0.327584291023472
GO:0015932	nucleobase-containing compound transmembrane transporter activity	11/2454	57/18639	0.192982456140351	1.46577017114914	0.122361107452748	0.328862661828058
GO:0002020	protease binding	23/2454	136/18639	0.169117647058824	1.28450848554581	0.122861334458039	0.329466717515279
GO:0000774	adenyl-nucleotide exchange factor activity	4/2454	15/18639	0.266666666666667	2.02542787286064	0.124662495743313	0.33206312897328
GO:0120283	protein serine/threonine kinase binding	4/2454	15/18639	0.266666666666667	2.02542787286064	0.124662495743313	0.33206312897328
GO:0140776	protein-containing complex destabilizing activity	4/2454	15/18639	0.266666666666667	2.02542787286064	0.124662495743313	0.33206312897328
GO:0003743	translation initiation factor activity	10/2454	51/18639	0.196078431372549	1.48928520063282	0.126159364704494	0.335303555970165
GO:0046915	transition metal ion transmembrane transporter activity	9/2454	45/18639	0.2	1.51907090464548	0.129668411978763	0.343837728090537
GO:0000217	DNA secondary structure binding	8/2454	39/18639	0.205128205128205	1.55802144066203	0.132653753437533	0.343837728090537
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	5/2454	21/18639	0.238095238095238	1.80841774362557	0.132759739901073	0.343837728090537
GO:0005123	death receptor binding	5/2454	21/18639	0.238095238095238	1.80841774362557	0.132759739901073	0.343837728090537
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	5/2454	21/18639	0.238095238095238	1.80841774362557	0.132759739901073	0.343837728090537
GO:0140312	cargo adaptor activity	5/2454	21/18639	0.238095238095238	1.80841774362557	0.132759739901073	0.343837728090537
GO:0008408	3'-5' exonuclease activity	11/2454	58/18639	0.189655172413793	1.44049827164657	0.134042431868161	0.343837728090537
GO:0051117	ATPase binding	15/2454	84/18639	0.178571428571429	1.35631330771918	0.134162082959088	0.343837728090537
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	3/2454	10/18639	0.3	2.27860635696821	0.134545197948471	0.343837728090537
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	3/2454	10/18639	0.3	2.27860635696821	0.134545197948471	0.343837728090537
GO:0008140	cAMP response element binding protein binding	3/2454	10/18639	0.3	2.27860635696821	0.134545197948471	0.343837728090537
GO:0015279	store-operated calcium channel activity	3/2454	10/18639	0.3	2.27860635696821	0.134545197948471	0.343837728090537
GO:0015924	mannosyl-oligosaccharide mannosidase activity	3/2454	10/18639	0.3	2.27860635696821	0.134545197948471	0.343837728090537
GO:0016303	1-phosphatidylinositol-3-kinase activity	3/2454	10/18639	0.3	2.27860635696821	0.134545197948471	0.343837728090537
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	3/2454	10/18639	0.3	2.27860635696821	0.134545197948471	0.343837728090537
GO:0032395	MHC class II receptor activity	3/2454	10/18639	0.3	2.27860635696821	0.134545197948471	0.343837728090537
GO:0035256	G protein-coupled glutamate receptor binding	3/2454	10/18639	0.3	2.27860635696821	0.134545197948471	0.343837728090537
GO:0051880	G-quadruplex DNA binding	3/2454	10/18639	0.3	2.27860635696821	0.134545197948471	0.343837728090537
GO:0005385	zinc ion transmembrane transporter activity	6/2454	27/18639	0.222222222222222	1.6878565607172	0.135194221300026	0.344026146116661
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	6/2454	27/18639	0.222222222222222	1.6878565607172	0.135194221300026	0.344026146116661
GO:0005200	structural constituent of cytoskeleton	19/2454	112/18639	0.169642857142857	1.28849764233322	0.146680813005977	0.372463380796493
GO:0043178	alcohol binding	16/2454	92/18639	0.173913043478261	1.32093122143085	0.147791126647488	0.37295507224689
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	8/2454	40/18639	0.2	1.51907090464548	0.147809953382129	0.37295507224689
GO:0071949	FAD binding	8/2454	40/18639	0.2	1.51907090464548	0.147809953382129	0.37295507224689
GO:0004707	MAP kinase activity	4/2454	16/18639	0.25	1.89883863080685	0.149785027113724	0.37321435922503
GO:0017070	U6 snRNA binding	4/2454	16/18639	0.25	1.89883863080685	0.149785027113724	0.37321435922503
GO:0022858	alanine transmembrane transporter activity	4/2454	16/18639	0.25	1.89883863080685	0.149785027113724	0.37321435922503
GO:0070411	I-SMAD binding	4/2454	16/18639	0.25	1.89883863080685	0.149785027113724	0.37321435922503
GO:0097027	ubiquitin-protein transferase activator activity	4/2454	16/18639	0.25	1.89883863080685	0.149785027113724	0.37321435922503
GO:0140327	flippase activity	4/2454	16/18639	0.25	1.89883863080685	0.149785027113724	0.37321435922503
GO:0008376	acetylgalactosaminyltransferase activity	7/2454	34/18639	0.205882352941176	1.56374946066446	0.15151667755649	0.375962544310294
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	7/2454	34/18639	0.205882352941176	1.56374946066446	0.15151667755649	0.375962544310294
GO:0051018	protein kinase A binding	10/2454	53/18639	0.188679245283019	1.43308575909951	0.152122095787587	0.376683284807359
GO:0031683	G-protein beta/gamma-subunit complex binding	5/2454	22/18639	0.227272727272727	1.72621693709713	0.154238964372828	0.380350105958562
GO:0140517	protein-RNA adaptor activity	5/2454	22/18639	0.227272727272727	1.72621693709713	0.154238964372828	0.380350105958562
GO:0140359	ABC-type transporter activity	9/2454	47/18639	0.191489361702128	1.45442958955418	0.157986639272155	0.38879016578086
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	10/2454	54/18639	0.185185185185185	1.406547133931	0.166035686075435	0.399638862152844
GO:0004540	RNA nuclease activity	20/2454	121/18639	0.165289256198347	1.25543049970701	0.166901957027299	0.399638862152844
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	3/2454	11/18639	0.272727272727273	2.07146032451656	0.167741395318334	0.399638862152844
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	3/2454	11/18639	0.272727272727273	2.07146032451656	0.167741395318334	0.399638862152844
GO:0003953	NAD+ nucleosidase activity	3/2454	11/18639	0.272727272727273	2.07146032451656	0.167741395318334	0.399638862152844
GO:0005536	D-glucose binding	3/2454	11/18639	0.272727272727273	2.07146032451656	0.167741395318334	0.399638862152844
GO:0008432	JUN kinase binding	3/2454	11/18639	0.272727272727273	2.07146032451656	0.167741395318334	0.399638862152844
GO:0008526	phosphatidylinositol transfer activity	3/2454	11/18639	0.272727272727273	2.07146032451656	0.167741395318334	0.399638862152844
GO:0010854	adenylate cyclase regulator activity	3/2454	11/18639	0.272727272727273	2.07146032451656	0.167741395318334	0.399638862152844
GO:0015173	aromatic amino acid transmembrane transporter activity	3/2454	11/18639	0.272727272727273	2.07146032451656	0.167741395318334	0.399638862152844
GO:0032050	clathrin heavy chain binding	3/2454	11/18639	0.272727272727273	2.07146032451656	0.167741395318334	0.399638862152844
GO:0034056	estrogen response element binding	3/2454	11/18639	0.272727272727273	2.07146032451656	0.167741395318334	0.399638862152844
GO:0034511	U3 snoRNA binding	3/2454	11/18639	0.272727272727273	2.07146032451656	0.167741395318334	0.399638862152844
GO:0034713	type I transforming growth factor beta receptor binding	3/2454	11/18639	0.272727272727273	2.07146032451656	0.167741395318334	0.399638862152844
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	3/2454	11/18639	0.272727272727273	2.07146032451656	0.167741395318334	0.399638862152844
GO:0047676	arachidonate-CoA ligase activity	3/2454	11/18639	0.272727272727273	2.07146032451656	0.167741395318334	0.399638862152844
GO:0008429	phosphatidylethanolamine binding	4/2454	17/18639	0.235294117647059	1.78714224075938	0.176637294977939	0.416711976125912
GO:0000295	adenine nucleotide transmembrane transporter activity	5/2454	23/18639	0.217391304347826	1.65116402678856	0.177037942092431	0.416711976125912
GO:0003887	DNA-directed DNA polymerase activity	5/2454	23/18639	0.217391304347826	1.65116402678856	0.177037942092431	0.416711976125912
GO:0042171	lysophosphatidic acid acyltransferase activity	5/2454	23/18639	0.217391304347826	1.65116402678856	0.177037942092431	0.416711976125912
GO:0043274	phospholipase binding	5/2454	23/18639	0.217391304347826	1.65116402678856	0.177037942092431	0.416711976125912
GO:0071617	lysophospholipid acyltransferase activity	5/2454	23/18639	0.217391304347826	1.65116402678856	0.177037942092431	0.416711976125912
GO:0005548	phospholipid transporter activity	12/2454	68/18639	0.176470588235294	1.34035668056954	0.177694906207538	0.416711976125912
GO:0030145	manganese ion binding	12/2454	68/18639	0.176470588235294	1.34035668056954	0.177694906207538	0.416711976125912
GO:0005484	SNAP receptor activity	7/2454	36/18639	0.194444444444444	1.47687449062755	0.187786355950376	0.439515619797749
GO:0016741	transferase activity, transferring one-carbon groups	33/2454	215/18639	0.153488372093023	1.16579860123955	0.195503224567985	0.456683313639278
GO:0070840	dynein complex binding	5/2454	24/18639	0.208333333333333	1.58236552567237	0.201005990726982	0.463281259737957
GO:0000340	RNA 7-methylguanosine cap binding	3/2454	12/18639	0.25	1.89883863080685	0.202976070319974	0.463281259737957
GO:0004126	cytidine deaminase activity	3/2454	12/18639	0.25	1.89883863080685	0.202976070319974	0.463281259737957
GO:0005527	macrolide binding	3/2454	12/18639	0.25	1.89883863080685	0.202976070319974	0.463281259737957
GO:0016273	arginine N-methyltransferase activity	3/2454	12/18639	0.25	1.89883863080685	0.202976070319974	0.463281259737957
GO:0016274	protein-arginine N-methyltransferase activity	3/2454	12/18639	0.25	1.89883863080685	0.202976070319974	0.463281259737957
GO:0034452	dynactin binding	3/2454	12/18639	0.25	1.89883863080685	0.202976070319974	0.463281259737957
GO:0035014	phosphatidylinositol 3-kinase regulator activity	3/2454	12/18639	0.25	1.89883863080685	0.202976070319974	0.463281259737957
GO:0042301	phosphate ion binding	3/2454	12/18639	0.25	1.89883863080685	0.202976070319974	0.463281259737957
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	3/2454	12/18639	0.25	1.89883863080685	0.202976070319974	0.463281259737957
GO:0097677	STAT family protein binding	3/2454	12/18639	0.25	1.89883863080685	0.202976070319974	0.463281259737957
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	3/2454	12/18639	0.25	1.89883863080685	0.202976070319974	0.463281259737957
GO:0008409	5'-3' exonuclease activity	4/2454	18/18639	0.222222222222222	1.6878565607172	0.204953775064094	0.465132286483219
GO:0035615	clathrin adaptor activity	4/2454	18/18639	0.222222222222222	1.6878565607172	0.204953775064094	0.465132286483219
GO:0050811	GABA receptor binding	4/2454	18/18639	0.222222222222222	1.6878565607172	0.204953775064094	0.465132286483219
GO:0016248	channel inhibitor activity	8/2454	44/18639	0.181818181818182	1.38097354967771	0.215953120374394	0.489166537817756
GO:0070325	lipoprotein particle receptor binding	6/2454	31/18639	0.193548387096774	1.47006861739885	0.216601799056146	0.489708415257374
GO:0005126	cytokine receptor binding	41/2454	275/18639	0.149090909090909	1.13239831073572	0.217618027360755	0.491077661742383
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	4/2454	19/18639	0.210526315789474	1.59902200488998	0.234462768102484	0.520580132013091
GO:0005520	insulin-like growth factor binding	4/2454	19/18639	0.210526315789474	1.59902200488998	0.234462768102484	0.520580132013091
GO:0008574	plus-end-directed microtubule motor activity	4/2454	19/18639	0.210526315789474	1.59902200488998	0.234462768102484	0.520580132013091
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	4/2454	19/18639	0.210526315789474	1.59902200488998	0.234462768102484	0.520580132013091
GO:0022821	solute:potassium antiporter activity	4/2454	19/18639	0.210526315789474	1.59902200488998	0.234462768102484	0.520580132013091
GO:0046624	sphingolipid transporter activity	4/2454	19/18639	0.210526315789474	1.59902200488998	0.234462768102484	0.520580132013091
GO:0050145	nucleoside monophosphate kinase activity	4/2454	19/18639	0.210526315789474	1.59902200488998	0.234462768102484	0.520580132013091
GO:0140303	intramembrane lipid transporter activity	8/2454	45/18639	0.177777777777778	1.35028524857376	0.234609273541017	0.520580132013091
GO:0141110	transporter inhibitor activity	8/2454	45/18639	0.177777777777778	1.35028524857376	0.234609273541017	0.520580132013091
GO:0031369	translation initiation factor binding	6/2454	32/18639	0.1875	1.42412897310513	0.239147160028264	0.528919153380438
GO:0008035	high-density lipoprotein particle binding	3/2454	13/18639	0.230769230769231	1.75277412074478	0.239694131381436	0.528919153380438
GO:0030955	potassium ion binding	3/2454	13/18639	0.230769230769231	1.75277412074478	0.239694131381436	0.528919153380438
GO:0004857	enzyme inhibitor activity	60/2454	416/18639	0.144230769230769	1.09548382546549	0.24117229807746	0.531200862800446
GO:0016776	phosphotransferase activity, phosphate group as acceptor	7/2454	39/18639	0.179487179487179	1.36326876057927	0.247858215623674	0.544923576996167
GO:0048306	calcium-dependent protein binding	13/2454	80/18639	0.1625	1.23424511002445	0.249792012251236	0.548167425050418
GO:0008157	protein phosphatase 1 binding	5/2454	26/18639	0.192307692307692	1.46064510062065	0.251806955576848	0.549564085529033
GO:0034237	protein kinase A regulatory subunit binding	5/2454	26/18639	0.192307692307692	1.46064510062065	0.251806955576848	0.549564085529033
GO:0050750	low-density lipoprotein particle receptor binding	5/2454	26/18639	0.192307692307692	1.46064510062065	0.251806955576848	0.549564085529033
GO:0016860	intramolecular oxidoreductase activity	9/2454	53/18639	0.169811320754717	1.28977718318956	0.257888144495128	0.561810966878275
GO:0019239	deaminase activity	6/2454	33/18639	0.181818181818182	1.38097354967771	0.262352157777717	0.570496692185727
GO:0030742	GTP-dependent protein binding	4/2454	20/18639	0.2	1.51907090464548	0.264893917173324	0.574978448165689
GO:0030331	nuclear estrogen receptor binding	7/2454	40/18639	0.175	1.32918704156479	0.269080574280972	0.583007910942106
GO:0005161	platelet-derived growth factor receptor binding	3/2454	14/18639	0.214285714285714	1.62757596926301	0.277377966732308	0.589243424887817
GO:0005347	ATP transmembrane transporter activity	3/2454	14/18639	0.214285714285714	1.62757596926301	0.277377966732308	0.589243424887817
GO:0008559	ABC-type xenobiotic transporter activity	3/2454	14/18639	0.214285714285714	1.62757596926301	0.277377966732308	0.589243424887817
GO:0019992	diacylglycerol binding	3/2454	14/18639	0.214285714285714	1.62757596926301	0.277377966732308	0.589243424887817
GO:0030983	mismatched DNA binding	3/2454	14/18639	0.214285714285714	1.62757596926301	0.277377966732308	0.589243424887817
GO:0034236	protein kinase A catalytic subunit binding	3/2454	14/18639	0.214285714285714	1.62757596926301	0.277377966732308	0.589243424887817
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	3/2454	14/18639	0.214285714285714	1.62757596926301	0.277377966732308	0.589243424887817
GO:0061665	SUMO ligase activity	3/2454	14/18639	0.214285714285714	1.62757596926301	0.277377966732308	0.589243424887817
GO:0070742	C2H2 zinc finger domain binding	3/2454	14/18639	0.214285714285714	1.62757596926301	0.277377966732308	0.589243424887817
GO:0071933	Arp2/3 complex binding	3/2454	14/18639	0.214285714285714	1.62757596926301	0.277377966732308	0.589243424887817
GO:0098847	sequence-specific single stranded DNA binding	3/2454	14/18639	0.214285714285714	1.62757596926301	0.277377966732308	0.589243424887817
GO:0035255	ionotropic glutamate receptor binding	5/2454	27/18639	0.185185185185185	1.406547133931	0.278309849730671	0.590174787726742
GO:0140767	enzyme-substrate adaptor activity	21/2454	139/18639	0.151079136690647	1.1474996042286	0.282733772587405	0.598494853123073
GO:0051959	dynein light intermediate chain binding	5/2454	28/18639	0.178571428571429	1.35631330771918	0.305328158422638	0.645181055606847
GO:0042626	ATPase-coupled transmembrane transporter activity	15/2454	98/18639	0.153061224489796	1.16255426375929	0.306326074259615	0.64614812136596
GO:0034061	DNA polymerase activity	6/2454	35/18639	0.171428571428571	1.30206077541041	0.310284160090406	0.651823789356735
GO:0019212	phosphatase inhibitor activity	9/2454	56/18639	0.160714285714286	1.22068197694726	0.314019585975033	0.651823789356735
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	33/2454	229/18639	0.14410480349345	1.09452707103277	0.315438331448127	0.651823789356735
GO:0004467	long-chain fatty acid-CoA ligase activity	3/2454	15/18639	0.2	1.51907090464548	0.315556834479557	0.651823789356735
GO:0004559	alpha-mannosidase activity	3/2454	15/18639	0.2	1.51907090464548	0.315556834479557	0.651823789356735
GO:0005402	carbohydrate:monoatomic cation symporter activity	3/2454	15/18639	0.2	1.51907090464548	0.315556834479557	0.651823789356735
GO:0010181	FMN binding	3/2454	15/18639	0.2	1.51907090464548	0.315556834479557	0.651823789356735
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	3/2454	15/18639	0.2	1.51907090464548	0.315556834479557	0.651823789356735
GO:0031386	protein tag activity	3/2454	15/18639	0.2	1.51907090464548	0.315556834479557	0.651823789356735
GO:0141047	molecular tag activity	3/2454	15/18639	0.2	1.51907090464548	0.315556834479557	0.651823789356735
GO:0141050	histone H3K deacetylase activity	3/2454	15/18639	0.2	1.51907090464548	0.315556834479557	0.651823789356735
GO:0141051	histone H4K deacetylase activity	3/2454	15/18639	0.2	1.51907090464548	0.315556834479557	0.651823789356735
GO:0004407	histone deacetylase activity	4/2454	22/18639	0.181818181818182	1.38097354967771	0.327483277926238	0.668378840272663
GO:0008093	cytoskeletal anchor activity	4/2454	22/18639	0.181818181818182	1.38097354967771	0.327483277926238	0.668378840272663
GO:0008970	phospholipase A1 activity	4/2454	22/18639	0.181818181818182	1.38097354967771	0.327483277926238	0.668378840272663
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	4/2454	22/18639	0.181818181818182	1.38097354967771	0.327483277926238	0.668378840272663
GO:0033558	protein lysine deacetylase activity	4/2454	22/18639	0.181818181818182	1.38097354967771	0.327483277926238	0.668378840272663
GO:0034062	5'-3' RNA polymerase activity	4/2454	22/18639	0.181818181818182	1.38097354967771	0.327483277926238	0.668378840272663
GO:0097747	RNA polymerase activity	4/2454	22/18639	0.181818181818182	1.38097354967771	0.327483277926238	0.668378840272663
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	5/2454	29/18639	0.172413793103448	1.30954388331507	0.33270165917987	0.677131551410535
GO:0004518	nuclease activity	30/2454	209/18639	0.143540669856459	1.09024227606135	0.334172916545925	0.677131551410535
GO:0048020	CCR chemokine receptor binding	8/2454	50/18639	0.16	1.21525672371638	0.334550281032578	0.677131551410535
GO:0045505	dynein intermediate chain binding	6/2454	36/18639	0.166666666666667	1.2658924205379	0.334783720918411	0.677131551410535
GO:0055106	ubiquitin-protein transferase regulator activity	6/2454	36/18639	0.166666666666667	1.2658924205379	0.334783720918411	0.677131551410535
GO:0008200	ion channel inhibitor activity	7/2454	43/18639	0.162790697674419	1.23645306192074	0.335168794678125	0.677131551410535
GO:0005518	collagen binding	11/2454	72/18639	0.152777777777778	1.16040138549307	0.347060792430541	0.699974212052153
GO:0000062	fatty-acyl-CoA binding	3/2454	16/18639	0.1875	1.42412897310513	0.353811866948596	0.70292191506731
GO:0003688	DNA replication origin binding	3/2454	16/18639	0.1875	1.42412897310513	0.353811866948596	0.70292191506731
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	3/2454	16/18639	0.1875	1.42412897310513	0.353811866948596	0.70292191506731
GO:0015385	sodium:proton antiporter activity	3/2454	16/18639	0.1875	1.42412897310513	0.353811866948596	0.70292191506731
GO:0015923	mannosidase activity	3/2454	16/18639	0.1875	1.42412897310513	0.353811866948596	0.70292191506731
GO:0043023	ribosomal large subunit binding	3/2454	16/18639	0.1875	1.42412897310513	0.353811866948596	0.70292191506731
GO:0055102	lipase inhibitor activity	3/2454	16/18639	0.1875	1.42412897310513	0.353811866948596	0.70292191506731
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	3/2454	16/18639	0.1875	1.42412897310513	0.353811866948596	0.70292191506731
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	3/2454	16/18639	0.1875	1.42412897310513	0.353811866948596	0.70292191506731
GO:0016830	carbon-carbon lyase activity	8/2454	51/18639	0.156862745098039	1.19142816050626	0.355410085375567	0.704926139484541
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	4/2454	23/18639	0.173913043478261	1.32093122143085	0.359155980207038	0.71117641113844
GO:0031624	ubiquitin conjugating enzyme binding	5/2454	30/18639	0.166666666666667	1.2658924205379	0.360276320601452	0.712215668494771
GO:0001786	phosphatidylserine binding	9/2454	59/18639	0.152542372881356	1.15861340184825	0.372406298640629	0.726459386978737
GO:0005080	protein kinase C binding	8/2454	52/18639	0.153846153846154	1.16851608049652	0.376406851430562	0.726459386978737
GO:0004896	cytokine receptor activity	14/2454	96/18639	0.145833333333333	1.10765586797066	0.384145898467609	0.726459386978737
GO:0000146	microfilament motor activity	6/2454	38/18639	0.157894736842105	1.19926650366748	0.384299096131565	0.726459386978737
GO:0001094	TFIID-class transcription factor complex binding	2/2454	10/18639	0.2	1.51907090464548	0.386752359776848	0.726459386978737
GO:0003680	minor groove of adenine-thymine-rich DNA binding	2/2454	10/18639	0.2	1.51907090464548	0.386752359776848	0.726459386978737
GO:0004862	cAMP-dependent protein kinase inhibitor activity	2/2454	10/18639	0.2	1.51907090464548	0.386752359776848	0.726459386978737
GO:0004955	prostaglandin receptor activity	2/2454	10/18639	0.2	1.51907090464548	0.386752359776848	0.726459386978737
GO:0005131	growth hormone receptor binding	2/2454	10/18639	0.2	1.51907090464548	0.386752359776848	0.726459386978737
GO:0005522	profilin binding	2/2454	10/18639	0.2	1.51907090464548	0.386752359776848	0.726459386978737
GO:0005528	FK506 binding	2/2454	10/18639	0.2	1.51907090464548	0.386752359776848	0.726459386978737
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	2/2454	10/18639	0.2	1.51907090464548	0.386752359776848	0.726459386978737
GO:0008519	ammonium channel activity	2/2454	10/18639	0.2	1.51907090464548	0.386752359776848	0.726459386978737
GO:0008641	ubiquitin-like modifier activating enzyme activity	2/2454	10/18639	0.2	1.51907090464548	0.386752359776848	0.726459386978737
GO:0015643	toxic substance binding	2/2454	10/18639	0.2	1.51907090464548	0.386752359776848	0.726459386978737
GO:0015658	branched-chain amino acid transmembrane transporter activity	2/2454	10/18639	0.2	1.51907090464548	0.386752359776848	0.726459386978737
GO:0031419	cobalamin binding	2/2454	10/18639	0.2	1.51907090464548	0.386752359776848	0.726459386978737
GO:0031957	very long-chain fatty acid-CoA ligase activity	2/2454	10/18639	0.2	1.51907090464548	0.386752359776848	0.726459386978737
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	2/2454	10/18639	0.2	1.51907090464548	0.386752359776848	0.726459386978737
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	2/2454	10/18639	0.2	1.51907090464548	0.386752359776848	0.726459386978737
GO:0047429	nucleoside triphosphate diphosphatase activity	2/2454	10/18639	0.2	1.51907090464548	0.386752359776848	0.726459386978737
GO:0050308	sugar-phosphatase activity	2/2454	10/18639	0.2	1.51907090464548	0.386752359776848	0.726459386978737
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	2/2454	10/18639	0.2	1.51907090464548	0.386752359776848	0.726459386978737
GO:0070097	delta-catenin binding	2/2454	10/18639	0.2	1.51907090464548	0.386752359776848	0.726459386978737
GO:0098505	G-rich strand telomeric DNA binding	2/2454	10/18639	0.2	1.51907090464548	0.386752359776848	0.726459386978737
GO:0008173	RNA methyltransferase activity	10/2454	67/18639	0.149253731343284	1.13363500346677	0.387023090966829	0.726459386978737
GO:0005452	solute:inorganic anion antiporter activity	5/2454	31/18639	0.161290322580645	1.22505718116571	0.387906036283242	0.726459386978737
GO:0008327	methyl-CpG binding	5/2454	31/18639	0.161290322580645	1.22505718116571	0.387906036283242	0.726459386978737
GO:0016411	acylglycerol O-acyltransferase activity	5/2454	31/18639	0.161290322580645	1.22505718116571	0.387906036283242	0.726459386978737
GO:0072349	modified amino acid transmembrane transporter activity	5/2454	31/18639	0.161290322580645	1.22505718116571	0.387906036283242	0.726459386978737
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	4/2454	24/18639	0.166666666666667	1.2658924205379	0.39078597810305	0.726459386978737
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	4/2454	24/18639	0.166666666666667	1.2658924205379	0.39078597810305	0.726459386978737
GO:0019957	C-C chemokine binding	4/2454	24/18639	0.166666666666667	1.2658924205379	0.39078597810305	0.726459386978737
GO:0030552	cAMP binding	4/2454	24/18639	0.166666666666667	1.2658924205379	0.39078597810305	0.726459386978737
GO:0005092	GDP-dissociation inhibitor activity	3/2454	17/18639	0.176470588235294	1.34035668056954	0.391777846656593	0.726459386978737
GO:0008484	sulfuric ester hydrolase activity	3/2454	17/18639	0.176470588235294	1.34035668056954	0.391777846656593	0.726459386978737
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	3/2454	17/18639	0.176470588235294	1.34035668056954	0.391777846656593	0.726459386978737
GO:0015278	intracellularly gated calcium channel activity	3/2454	17/18639	0.176470588235294	1.34035668056954	0.391777846656593	0.726459386978737
GO:0031489	myosin V binding	3/2454	17/18639	0.176470588235294	1.34035668056954	0.391777846656593	0.726459386978737
GO:1901567	fatty acid derivative binding	3/2454	17/18639	0.176470588235294	1.34035668056954	0.391777846656593	0.726459386978737
GO:0016757	glycosyltransferase activity	37/2454	267/18639	0.138576779026217	1.05253976539106	0.395159460155431	0.731595533043181
GO:0004864	protein phosphatase inhibitor activity	8/2454	53/18639	0.150943396226415	1.14646860727961	0.397476843774639	0.733614668448254
GO:0005544	calcium-dependent phospholipid binding	8/2454	53/18639	0.150943396226415	1.14646860727961	0.397476843774639	0.733614668448254
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	6/2454	39/18639	0.153846153846154	1.16851608049652	0.40910652895118	0.753915883860727
GO:0015026	coreceptor activity	9/2454	61/18639	0.147540983606557	1.12062607719748	0.411874163628871	0.757848461077122
GO:0022884	macromolecule transmembrane transporter activity	5/2454	32/18639	0.15625	1.18677414425428	0.41545397633046	0.759759871087508
GO:0043425	bHLH transcription factor binding	5/2454	32/18639	0.15625	1.18677414425428	0.41545397633046	0.759759871087508
GO:0071813	lipoprotein particle binding	5/2454	32/18639	0.15625	1.18677414425428	0.41545397633046	0.759759871087508
GO:0071814	protein-lipid complex binding	5/2454	32/18639	0.15625	1.18677414425428	0.41545397633046	0.759759871087508
GO:0051287	NAD binding	8/2454	54/18639	0.148148148148148	1.1252377071448	0.418558271182566	0.764268232571524
GO:0008013	beta-catenin binding	15/2454	106/18639	0.141509433962264	1.07481431932463	0.424313342547793	0.76695739283632
GO:0000400	four-way junction DNA binding	3/2454	18/18639	0.166666666666667	1.2658924205379	0.429142660975093	0.76695739283632
GO:0008308	voltage-gated monoatomic anion channel activity	3/2454	18/18639	0.166666666666667	1.2658924205379	0.429142660975093	0.76695739283632
GO:0031690	adrenergic receptor binding	3/2454	18/18639	0.166666666666667	1.2658924205379	0.429142660975093	0.76695739283632
GO:0070064	proline-rich region binding	3/2454	18/18639	0.166666666666667	1.2658924205379	0.429142660975093	0.76695739283632
GO:0098641	cadherin binding involved in cell-cell adhesion	3/2454	18/18639	0.166666666666667	1.2658924205379	0.429142660975093	0.76695739283632
GO:1901611	phosphatidylglycerol binding	3/2454	18/18639	0.166666666666667	1.2658924205379	0.429142660975093	0.76695739283632
GO:1990381	ubiquitin-specific protease binding	3/2454	18/18639	0.166666666666667	1.2658924205379	0.429142660975093	0.76695739283632
GO:0001851	complement component C3b binding	2/2454	11/18639	0.181818181818182	1.38097354967771	0.435421462989851	0.76695739283632
GO:0002162	dystroglycan binding	2/2454	11/18639	0.181818181818182	1.38097354967771	0.435421462989851	0.76695739283632
GO:0004143	ATP-dependent diacylglycerol kinase activity	2/2454	11/18639	0.181818181818182	1.38097354967771	0.435421462989851	0.76695739283632
GO:0004954	prostanoid receptor activity	2/2454	11/18639	0.181818181818182	1.38097354967771	0.435421462989851	0.76695739283632
GO:0005225	volume-sensitive anion channel activity	2/2454	11/18639	0.181818181818182	1.38097354967771	0.435421462989851	0.76695739283632
GO:0008172	S-methyltransferase activity	2/2454	11/18639	0.181818181818182	1.38097354967771	0.435421462989851	0.76695739283632
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/2454	11/18639	0.181818181818182	1.38097354967771	0.435421462989851	0.76695739283632
GO:0019203	carbohydrate phosphatase activity	2/2454	11/18639	0.181818181818182	1.38097354967771	0.435421462989851	0.76695739283632
GO:0019215	intermediate filament binding	2/2454	11/18639	0.181818181818182	1.38097354967771	0.435421462989851	0.76695739283632
GO:0032794	GTPase activating protein binding	2/2454	11/18639	0.181818181818182	1.38097354967771	0.435421462989851	0.76695739283632
GO:0035252	UDP-xylosyltransferase activity	2/2454	11/18639	0.181818181818182	1.38097354967771	0.435421462989851	0.76695739283632
GO:0042285	xylosyltransferase activity	2/2454	11/18639	0.181818181818182	1.38097354967771	0.435421462989851	0.76695739283632
GO:0050786	RAGE receptor binding	2/2454	11/18639	0.181818181818182	1.38097354967771	0.435421462989851	0.76695739283632
GO:0070697	activin receptor binding	2/2454	11/18639	0.181818181818182	1.38097354967771	0.435421462989851	0.76695739283632
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	2/2454	11/18639	0.181818181818182	1.38097354967771	0.435421462989851	0.76695739283632
GO:0180030	inositol phosphate kinase activity	2/2454	11/18639	0.181818181818182	1.38097354967771	0.435421462989851	0.76695739283632
GO:0099106	ion channel regulator activity	22/2454	160/18639	0.1375	1.04436124694377	0.448238924805461	0.788373167746076
GO:0004112	cyclic-nucleotide phosphodiesterase activity	4/2454	26/18639	0.153846153846154	1.16851608049652	0.453153228591179	0.791198921744599
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	4/2454	26/18639	0.153846153846154	1.16851608049652	0.453153228591179	0.791198921744599
GO:0030507	spectrin binding	4/2454	26/18639	0.153846153846154	1.16851608049652	0.453153228591179	0.791198921744599
GO:0051139	metal cation:proton antiporter activity	4/2454	26/18639	0.153846153846154	1.16851608049652	0.453153228591179	0.791198921744599
GO:0120014	phospholipid transfer activity	4/2454	26/18639	0.153846153846154	1.16851608049652	0.453153228591179	0.791198921744599
GO:0016247	channel regulator activity	23/2454	168/18639	0.136904761904762	1.0398402025847	0.454278718702182	0.792007795288353
GO:0001530	lipopolysaccharide binding	6/2454	41/18639	0.146341463414634	1.11151529608206	0.458340502406074	0.795609928704883
GO:0015175	neutral L-amino acid transmembrane transporter activity	6/2454	41/18639	0.146341463414634	1.11151529608206	0.458340502406074	0.795609928704883
GO:0140828	metal cation:monoatomic cation antiporter activity	6/2454	41/18639	0.146341463414634	1.11151529608206	0.458340502406074	0.795609928704883
GO:0005178	integrin binding	22/2454	161/18639	0.136645962732919	1.03787453112424	0.460538065580804	0.79826598034006
GO:0003756	protein disulfide isomerase activity	3/2454	19/18639	0.157894736842105	1.19926650366748	0.465645140888707	0.80131163813366
GO:0005346	purine ribonucleotide transmembrane transporter activity	3/2454	19/18639	0.157894736842105	1.19926650366748	0.465645140888707	0.80131163813366
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	3/2454	19/18639	0.157894736842105	1.19926650366748	0.465645140888707	0.80131163813366
GO:0097001	ceramide binding	3/2454	19/18639	0.157894736842105	1.19926650366748	0.465645140888707	0.80131163813366
GO:0120227	acyl-CoA binding	3/2454	19/18639	0.157894736842105	1.19926650366748	0.465645140888707	0.80131163813366
GO:0016831	carboxy-lyase activity	5/2454	34/18639	0.147058823529412	1.11696390047462	0.469809271089959	0.805485632587794
GO:0051427	hormone receptor binding	5/2454	34/18639	0.147058823529412	1.11696390047462	0.469809271089959	0.805485632587794
GO:0016835	carbon-oxygen lyase activity	11/2454	79/18639	0.139240506329114	1.05758100956331	0.470525860086294	0.805485632587794
GO:0141108	transporter regulator activity	23/2454	170/18639	0.135294117647059	1.02760678843665	0.478291279467314	0.805485632587794
GO:0042379	chemokine receptor binding	10/2454	72/18639	0.138888888888889	1.05491035044825	0.479951244078147	0.805485632587794
GO:0004000	adenosine deaminase activity	2/2454	12/18639	0.166666666666667	1.2658924205379	0.481910541523826	0.805485632587794
GO:0004859	phospholipase inhibitor activity	2/2454	12/18639	0.166666666666667	1.2658924205379	0.481910541523826	0.805485632587794
GO:0005165	neurotrophin receptor binding	2/2454	12/18639	0.166666666666667	1.2658924205379	0.481910541523826	0.805485632587794
GO:0005436	sodium:phosphate symporter activity	2/2454	12/18639	0.166666666666667	1.2658924205379	0.481910541523826	0.805485632587794
GO:0008603	cAMP-dependent protein kinase regulator activity	2/2454	12/18639	0.166666666666667	1.2658924205379	0.481910541523826	0.805485632587794
GO:0010853	cyclase activator activity	2/2454	12/18639	0.166666666666667	1.2658924205379	0.481910541523826	0.805485632587794
GO:0015132	prostaglandin transmembrane transporter activity	2/2454	12/18639	0.166666666666667	1.2658924205379	0.481910541523826	0.805485632587794
GO:0015368	calcium:monoatomic cation antiporter activity	2/2454	12/18639	0.166666666666667	1.2658924205379	0.481910541523826	0.805485632587794
GO:0017166	vinculin binding	2/2454	12/18639	0.166666666666667	1.2658924205379	0.481910541523826	0.805485632587794
GO:0035497	cAMP response element binding	2/2454	12/18639	0.166666666666667	1.2658924205379	0.481910541523826	0.805485632587794
GO:0043047	single-stranded telomeric DNA binding	2/2454	12/18639	0.166666666666667	1.2658924205379	0.481910541523826	0.805485632587794
GO:0070008	serine-type exopeptidase activity	2/2454	12/18639	0.166666666666667	1.2658924205379	0.481910541523826	0.805485632587794
GO:0070679	inositol 1,4,5 trisphosphate binding	2/2454	12/18639	0.166666666666667	1.2658924205379	0.481910541523826	0.805485632587794
GO:0141221	histone deacetylase activity, hydrolytic mechanism	2/2454	12/18639	0.166666666666667	1.2658924205379	0.481910541523826	0.805485632587794
GO:0004175	endopeptidase activity	54/2454	405/18639	0.133333333333333	1.01271393643032	0.482489500068923	0.805485632587794
GO:0008307	structural constituent of muscle	6/2454	42/18639	0.142857142857143	1.08505064617534	0.48259377145523	0.805485632587794
GO:0004683	calcium/calmodulin-dependent protein kinase activity	4/2454	27/18639	0.148148148148148	1.1252377071448	0.483560772740833	0.805485632587794
GO:0008320	protein transmembrane transporter activity	4/2454	27/18639	0.148148148148148	1.1252377071448	0.483560772740833	0.805485632587794
GO:0000339	RNA cap binding	3/2454	20/18639	0.15	1.13930317848411	0.501071827426717	0.828882303737694
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	3/2454	20/18639	0.15	1.13930317848411	0.501071827426717	0.828882303737694
GO:0010851	cyclase regulator activity	3/2454	20/18639	0.15	1.13930317848411	0.501071827426717	0.828882303737694
GO:0015095	magnesium ion transmembrane transporter activity	3/2454	20/18639	0.15	1.13930317848411	0.501071827426717	0.828882303737694
GO:0016505	peptidase activator activity involved in apoptotic process	3/2454	20/18639	0.15	1.13930317848411	0.501071827426717	0.828882303737694
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	4/2454	28/18639	0.142857142857143	1.08505064617534	0.513266208460532	0.847881747677896
GO:0015297	antiporter activity	18/2454	135/18639	0.133333333333333	1.01271393643032	0.515513917860786	0.850048739231947
GO:0015459	potassium channel regulator activity	8/2454	59/18639	0.135593220338983	1.02987857942066	0.522157000386912	0.850048739231947
GO:0070888	E-box binding	8/2454	59/18639	0.135593220338983	1.02987857942066	0.522157000386912	0.850048739231947
GO:0004869	cysteine-type endopeptidase inhibitor activity	5/2454	36/18639	0.138888888888889	1.05491035044825	0.522463413569155	0.850048739231947
GO:0044390	ubiquitin-like protein conjugating enzyme binding	5/2454	36/18639	0.138888888888889	1.05491035044825	0.522463413569155	0.850048739231947
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	5/2454	36/18639	0.138888888888889	1.05491035044825	0.522463413569155	0.850048739231947
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	5/2454	36/18639	0.138888888888889	1.05491035044825	0.522463413569155	0.850048739231947
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	5/2454	36/18639	0.138888888888889	1.05491035044825	0.522463413569155	0.850048739231947
GO:0019104	DNA N-glycosylase activity	2/2454	13/18639	0.153846153846154	1.16851608049652	0.525949888822442	0.850048739231947
GO:0031994	insulin-like growth factor I binding	2/2454	13/18639	0.153846153846154	1.16851608049652	0.525949888822442	0.850048739231947
GO:0035673	oligopeptide transmembrane transporter activity	2/2454	13/18639	0.153846153846154	1.16851608049652	0.525949888822442	0.850048739231947
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	2/2454	13/18639	0.153846153846154	1.16851608049652	0.525949888822442	0.850048739231947
GO:0051011	microtubule minus-end binding	2/2454	13/18639	0.153846153846154	1.16851608049652	0.525949888822442	0.850048739231947
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	2/2454	13/18639	0.153846153846154	1.16851608049652	0.525949888822442	0.850048739231947
GO:0061459	L-arginine transmembrane transporter activity	2/2454	13/18639	0.153846153846154	1.16851608049652	0.525949888822442	0.850048739231947
GO:0071714	icosanoid transmembrane transporter activity	2/2454	13/18639	0.153846153846154	1.16851608049652	0.525949888822442	0.850048739231947
GO:0019205	nucleobase-containing compound kinase activity	6/2454	44/18639	0.136363636363636	1.03573016225828	0.529991694921032	0.855425191802368
GO:0008373	sialyltransferase activity	3/2454	21/18639	0.142857142857143	1.08505064617534	0.535253080026899	0.860433714666897
GO:0019200	carbohydrate kinase activity	3/2454	21/18639	0.142857142857143	1.08505064617534	0.535253080026899	0.860433714666897
GO:0051428	peptide hormone receptor binding	3/2454	21/18639	0.142857142857143	1.08505064617534	0.535253080026899	0.860433714666897
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	16/2454	122/18639	0.131147540983607	0.996112068619985	0.547263277194571	0.877271394855882
GO:0003777	microtubule motor activity	9/2454	68/18639	0.132352941176471	1.00526751042715	0.547319029325565	0.877271394855882
GO:0070001	aspartic-type peptidase activity	5/2454	37/18639	0.135135135135135	1.02639925989559	0.547927869529552	0.877271394855882
GO:0008009	chemokine activity	6/2454	45/18639	0.133333333333333	1.01271393643032	0.553005497783637	0.8830368162206
GO:0051539	4 iron, 4 sulfur cluster binding	6/2454	45/18639	0.133333333333333	1.01271393643032	0.553005497783637	0.8830368162206
GO:0004065	arylsulfatase activity	2/2454	14/18639	0.142857142857143	1.08505064617534	0.567378542504131	0.896038340559838
GO:0008191	metalloendopeptidase inhibitor activity	2/2454	14/18639	0.142857142857143	1.08505064617534	0.567378542504131	0.896038340559838
GO:0008195	phosphatidate phosphatase activity	2/2454	14/18639	0.142857142857143	1.08505064617534	0.567378542504131	0.896038340559838
GO:0008474	palmitoyl-(protein) hydrolase activity	2/2454	14/18639	0.142857142857143	1.08505064617534	0.567378542504131	0.896038340559838
GO:0008494	translation activator activity	2/2454	14/18639	0.142857142857143	1.08505064617534	0.567378542504131	0.896038340559838
GO:0015386	potassium:proton antiporter activity	2/2454	14/18639	0.142857142857143	1.08505064617534	0.567378542504131	0.896038340559838
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	2/2454	14/18639	0.142857142857143	1.08505064617534	0.567378542504131	0.896038340559838
GO:0098599	palmitoyl hydrolase activity	2/2454	14/18639	0.142857142857143	1.08505064617534	0.567378542504131	0.896038340559838
GO:0001965	G-protein alpha-subunit binding	4/2454	30/18639	0.133333333333333	1.01271393643032	0.570138107998359	0.896038340559838
GO:0001968	fibronectin binding	4/2454	30/18639	0.133333333333333	1.01271393643032	0.570138107998359	0.896038340559838
GO:0016769	transferase activity, transferring nitrogenous groups	4/2454	30/18639	0.133333333333333	1.01271393643032	0.570138107998359	0.896038340559838
GO:0070566	adenylyltransferase activity	4/2454	30/18639	0.133333333333333	1.01271393643032	0.570138107998359	0.896038340559838
GO:0015294	solute:monoatomic cation symporter activity	15/2454	116/18639	0.129310344827586	0.9821579124863	0.571512115637801	0.89701901614542
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	7/2454	54/18639	0.12962962962963	0.984582993751698	0.57830742537547	0.906494994428653
GO:0015179	L-amino acid transmembrane transporter activity	8/2454	62/18639	0.129032258064516	0.980045744932566	0.58111937732201	0.909710438844403
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	11/2454	86/18639	0.127906976744186	0.971498834366293	0.589283758412301	0.920082735066726
GO:0050660	flavin adenine dinucleotide binding	11/2454	86/18639	0.127906976744186	0.971498834366293	0.589283758412301	0.920082735066726
GO:0016853	isomerase activity	23/2454	180/18639	0.127777777777778	0.970517522412388	0.594949718661495	0.924642769274824
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	5/2454	39/18639	0.128205128205128	0.973763400413767	0.596780928360245	0.924642769274824
GO:0070273	phosphatidylinositol-4-phosphate binding	4/2454	31/18639	0.129032258064516	0.980045744932566	0.597135451956154	0.924642769274824
GO:0008374	O-acyltransferase activity	7/2454	55/18639	0.127272727272727	0.966681484774394	0.598536802732383	0.924642769274824
GO:0005212	structural constituent of eye lens	3/2454	23/18639	0.130434782608696	0.990698416073137	0.599394266960261	0.924642769274824
GO:0016493	C-C chemokine receptor activity	3/2454	23/18639	0.130434782608696	0.990698416073137	0.599394266960261	0.924642769274824
GO:0015370	solute:sodium symporter activity	10/2454	79/18639	0.126582278481013	0.961437281421188	0.603442498382822	0.924642769274824
GO:0008081	phosphoric diester hydrolase activity	11/2454	87/18639	0.126436781609195	0.960332181097715	0.605297476114404	0.924642769274824
GO:0004953	icosanoid receptor activity	2/2454	15/18639	0.133333333333333	1.01271393643032	0.606120343738681	0.924642769274824
GO:0005041	low-density lipoprotein particle receptor activity	2/2454	15/18639	0.133333333333333	1.01271393643032	0.606120343738681	0.924642769274824
GO:0015556	C4-dicarboxylate transmembrane transporter activity	2/2454	15/18639	0.133333333333333	1.01271393643032	0.606120343738681	0.924642769274824
GO:0015929	hexosaminidase activity	2/2454	15/18639	0.133333333333333	1.01271393643032	0.606120343738681	0.924642769274824
GO:0033130	acetylcholine receptor binding	2/2454	15/18639	0.133333333333333	1.01271393643032	0.606120343738681	0.924642769274824
GO:0045504	dynein heavy chain binding	2/2454	15/18639	0.133333333333333	1.01271393643032	0.606120343738681	0.924642769274824
GO:0048531	beta-1,3-galactosyltransferase activity	2/2454	15/18639	0.133333333333333	1.01271393643032	0.606120343738681	0.924642769274824
GO:0050700	CARD domain binding	2/2454	15/18639	0.133333333333333	1.01271393643032	0.606120343738681	0.924642769274824
GO:0050780	dopamine receptor binding	2/2454	15/18639	0.133333333333333	1.01271393643032	0.606120343738681	0.924642769274824
GO:0140161	monocarboxylate:sodium symporter activity	2/2454	15/18639	0.133333333333333	1.01271393643032	0.606120343738681	0.924642769274824
GO:0003823	antigen binding	22/2454	174/18639	0.126436781609195	0.960332181097715	0.615022941955293	0.937028584176471
GO:0000049	tRNA binding	10/2454	80/18639	0.125	0.949419315403423	0.619930218077918	0.943303487049859
GO:0008378	galactosyltransferase activity	4/2454	32/18639	0.125	0.949419315403423	0.62308994847411	0.945705048699283
GO:0015106	bicarbonate transmembrane transporter activity	4/2454	32/18639	0.125	0.949419315403423	0.62308994847411	0.945705048699283
GO:0015295	solute:proton symporter activity	3/2454	24/18639	0.125	0.949419315403423	0.629195451082721	0.953761418878243
GO:0008296	3'-5'-DNA exonuclease activity	2/2454	16/18639	0.125	0.949419315403423	0.64216441185155	0.967830221686
GO:0015378	sodium:chloride symporter activity	2/2454	16/18639	0.125	0.949419315403423	0.64216441185155	0.967830221686
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	2/2454	16/18639	0.125	0.949419315403423	0.64216441185155	0.967830221686
GO:0016877	ligase activity, forming carbon-sulfur bonds	5/2454	41/18639	0.121951219512195	0.926262746735047	0.642522739146057	0.967830221686
GO:0140318	protein transporter activity	5/2454	41/18639	0.121951219512195	0.926262746735047	0.642522739146057	0.967830221686
GO:0000149	SNARE binding	13/2454	106/18639	0.122641509433962	0.931505743414679	0.651595525911248	0.980261948414909
GO:0000030	mannosyltransferase activity	3/2454	25/18639	0.12	0.911442542787286	0.657425256380818	0.981623728628538
GO:0003707	nuclear steroid receptor activity	3/2454	25/18639	0.12	0.911442542787286	0.657425256380818	0.981623728628538
GO:0008483	transaminase activity	3/2454	25/18639	0.12	0.911442542787286	0.657425256380818	0.981623728628538
GO:0015645	fatty acid ligase activity	3/2454	25/18639	0.12	0.911442542787286	0.657425256380818	0.981623728628538
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	3/2454	25/18639	0.12	0.911442542787286	0.657425256380818	0.981623728628538
GO:0120515	fatty acid-CoA ligase activity	3/2454	25/18639	0.12	0.911442542787286	0.657425256380818	0.981623728628538
GO:0016859	cis-trans isomerase activity	5/2454	42/18639	0.119047619047619	0.904208871812784	0.664134761806979	0.990405455263276
GO:0015085	calcium ion transmembrane transporter activity	18/2454	147/18639	0.122448979591837	0.930043411007435	0.666361777022145	0.991251334495091
GO:0001540	amyloid-beta binding	10/2454	83/18639	0.120481927710843	0.915102954605709	0.667188398217849	0.991251334495091
GO:0030165	PDZ domain binding	10/2454	83/18639	0.120481927710843	0.915102954605709	0.667188398217849	0.991251334495091
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	4/2454	34/18639	0.117647058823529	0.893571120379692	0.671711630963884	0.992576102585024
GO:0090482	vitamin transmembrane transporter activity	4/2454	34/18639	0.117647058823529	0.893571120379692	0.671711630963884	0.992576102585024
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	2/2454	17/18639	0.117647058823529	0.893571120379692	0.675549287210877	0.992576102585024
GO:0016018	cyclosporin A binding	2/2454	17/18639	0.117647058823529	0.893571120379692	0.675549287210877	0.992576102585024
GO:0019198	transmembrane receptor protein phosphatase activity	2/2454	17/18639	0.117647058823529	0.893571120379692	0.675549287210877	0.992576102585024
GO:0030169	low-density lipoprotein particle binding	2/2454	17/18639	0.117647058823529	0.893571120379692	0.675549287210877	0.992576102585024
GO:0032977	membrane insertase activity	2/2454	17/18639	0.117647058823529	0.893571120379692	0.675549287210877	0.992576102585024
GO:0038191	neuropilin binding	2/2454	17/18639	0.117647058823529	0.893571120379692	0.675549287210877	0.992576102585024
GO:0048038	quinone binding	2/2454	17/18639	0.117647058823529	0.893571120379692	0.675549287210877	0.992576102585024
GO:0140375	immune receptor activity	19/2454	156/18639	0.121794871794872	0.925075230393079	0.678055757577006	0.995036424616072
GO:0001637	G protein-coupled chemoattractant receptor activity	3/2454	26/18639	0.115384615384615	0.87638706037239	0.684069433918598	0.99821525690934
GO:0004529	DNA exonuclease activity	3/2454	26/18639	0.115384615384615	0.87638706037239	0.684069433918598	0.99821525690934
GO:0004950	chemokine receptor activity	3/2454	26/18639	0.115384615384615	0.87638706037239	0.684069433918598	0.99821525690934
GO:0015145	monosaccharide transmembrane transporter activity	3/2454	26/18639	0.115384615384615	0.87638706037239	0.684069433918598	0.99821525690934
GO:0098631	cell adhesion mediator activity	9/2454	76/18639	0.118421052631579	0.899449877750611	0.684395075807407	0.99821525690934
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	22/2454	181/18639	0.121546961325967	0.923192262491726	0.689616053278225	0.999999999999181
GO:0005343	organic acid:sodium symporter activity	4/2454	35/18639	0.114285714285714	0.868040516940272	0.694332900818593	0.999999999999181
GO:0003746	translation elongation factor activity	2/2454	18/18639	0.111111111111111	0.843928280358598	0.70635011549035	0.999999999999181
GO:0015373	monoatomic anion:sodium symporter activity	2/2454	18/18639	0.111111111111111	0.843928280358598	0.70635011549035	0.999999999999181
GO:0030228	lipoprotein particle receptor activity	2/2454	18/18639	0.111111111111111	0.843928280358598	0.70635011549035	0.999999999999181
GO:0034185	apolipoprotein binding	2/2454	18/18639	0.111111111111111	0.843928280358598	0.70635011549035	0.999999999999181
GO:0099602	neurotransmitter receptor regulator activity	2/2454	18/18639	0.111111111111111	0.843928280358598	0.70635011549035	0.999999999999181
GO:0016405	CoA-ligase activity	3/2454	27/18639	0.111111111111111	0.843928280358598	0.709133016565818	0.999999999999181
GO:0015291	secondary active transmembrane transporter activity	35/2454	287/18639	0.121951219512195	0.926262746735047	0.713620295327115	0.999999999999181
GO:1901505	carbohydrate derivative transmembrane transporter activity	6/2454	53/18639	0.113207547169811	0.859851455459704	0.714822667996472	0.999999999999181
GO:0004190	aspartic-type endopeptidase activity	4/2454	36/18639	0.111111111111111	0.843928280358598	0.715816586724773	0.999999999999181
GO:1902936	phosphatidylinositol bisphosphate binding	13/2454	111/18639	0.117117117117117	0.889546025242847	0.716491730591463	0.999999999999181
GO:0016829	lyase activity	24/2454	200/18639	0.12	0.911442542787286	0.718626738376555	0.999999999999181
GO:0019955	cytokine binding	17/2454	144/18639	0.118055555555556	0.896673797881011	0.722079875716762	0.999999999999181
GO:0046625	sphingolipid binding	3/2454	28/18639	0.107142857142857	0.813787984631505	0.732637033538452	0.999999999999181
GO:0050698	proteoglycan sulfotransferase activity	3/2454	28/18639	0.107142857142857	0.813787984631505	0.732637033538452	0.999999999999181
GO:0051119	sugar transmembrane transporter activity	3/2454	28/18639	0.107142857142857	0.813787984631505	0.732637033538452	0.999999999999181
GO:0008301	DNA binding, bending	2/2454	19/18639	0.105263157894737	0.799511002444988	0.734668347796426	0.999999999999181
GO:0008381	mechanosensitive monoatomic ion channel activity	2/2454	19/18639	0.105263157894737	0.799511002444988	0.734668347796426	0.999999999999181
GO:0030506	ankyrin binding	2/2454	19/18639	0.105263157894737	0.799511002444988	0.734668347796426	0.999999999999181
GO:0042577	lipid phosphatase activity	2/2454	19/18639	0.105263157894737	0.799511002444988	0.734668347796426	0.999999999999181
GO:0043395	heparan sulfate proteoglycan binding	2/2454	19/18639	0.105263157894737	0.799511002444988	0.734668347796426	0.999999999999181
GO:0070003	threonine-type peptidase activity	2/2454	19/18639	0.105263157894737	0.799511002444988	0.734668347796426	0.999999999999181
GO:0061134	peptidase regulator activity	27/2454	226/18639	0.119469026548673	0.907409611182033	0.735706350723703	0.999999999999181
GO:0019213	deacetylase activity	4/2454	37/18639	0.108108108108108	0.821119407916474	0.736166734263587	0.999999999999181
GO:0030551	cyclic nucleotide binding	4/2454	37/18639	0.108108108108108	0.821119407916474	0.736166734263587	0.999999999999181
GO:0042805	actinin binding	4/2454	37/18639	0.108108108108108	0.821119407916474	0.736166734263587	0.999999999999181
GO:0015293	symporter activity	17/2454	146/18639	0.116438356164384	0.884390595170312	0.742848548559703	0.999999999999181
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	15/2454	130/18639	0.115384615384615	0.87638706037239	0.746512038741473	0.999999999999181
GO:0098632	cell-cell adhesion mediator activity	6/2454	55/18639	0.109090909090909	0.828584129806624	0.748215677886348	0.999999999999181
GO:0003785	actin monomer binding	3/2454	29/18639	0.103448275862069	0.78572632998904	0.754615552445339	0.999999999999181
GO:0004629	phospholipase C activity	3/2454	29/18639	0.103448275862069	0.78572632998904	0.754615552445339	0.999999999999181
GO:0016417	S-acyltransferase activity	3/2454	29/18639	0.103448275862069	0.78572632998904	0.754615552445339	0.999999999999181
GO:0035250	UDP-galactosyltransferase activity	3/2454	29/18639	0.103448275862069	0.78572632998904	0.754615552445339	0.999999999999181
GO:0043236	laminin binding	3/2454	29/18639	0.103448275862069	0.78572632998904	0.754615552445339	0.999999999999181
GO:0099604	ligand-gated calcium channel activity	3/2454	29/18639	0.103448275862069	0.78572632998904	0.754615552445339	0.999999999999181
GO:0042887	amide transmembrane transporter activity	4/2454	38/18639	0.105263157894737	0.799511002444988	0.755395749127164	0.999999999999181
GO:0015101	organic cation transmembrane transporter activity	9/2454	81/18639	0.111111111111111	0.843928280358598	0.755665269531962	0.999999999999181
GO:0000182	rDNA binding	1/2454	10/18639	0.1	0.759535452322738	0.756363743288886	0.999999999999181
GO:0004090	carbonyl reductase (NADPH) activity	1/2454	10/18639	0.1	0.759535452322738	0.756363743288886	0.999999999999181
GO:0004382	GDP phosphatase activity	1/2454	10/18639	0.1	0.759535452322738	0.756363743288886	0.999999999999181
GO:0005337	nucleoside transmembrane transporter activity	1/2454	10/18639	0.1	0.759535452322738	0.756363743288886	0.999999999999181
GO:0005381	iron ion transmembrane transporter activity	1/2454	10/18639	0.1	0.759535452322738	0.756363743288886	0.999999999999181
GO:0008190	eukaryotic initiation factor 4E binding	1/2454	10/18639	0.1	0.759535452322738	0.756363743288886	0.999999999999181
GO:0008239	dipeptidyl-peptidase activity	1/2454	10/18639	0.1	0.759535452322738	0.756363743288886	0.999999999999181
GO:0015187	glycine transmembrane transporter activity	1/2454	10/18639	0.1	0.759535452322738	0.756363743288886	0.999999999999181
GO:0015203	polyamine transmembrane transporter activity	1/2454	10/18639	0.1	0.759535452322738	0.756363743288886	0.999999999999181
GO:0016427	tRNA (cytidine) methyltransferase activity	1/2454	10/18639	0.1	0.759535452322738	0.756363743288886	0.999999999999181
GO:0016783	sulfurtransferase activity	1/2454	10/18639	0.1	0.759535452322738	0.756363743288886	0.999999999999181
GO:0016868	intramolecular phosphotransferase activity	1/2454	10/18639	0.1	0.759535452322738	0.756363743288886	0.999999999999181
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	1/2454	10/18639	0.1	0.759535452322738	0.756363743288886	0.999999999999181
GO:0031434	mitogen-activated protein kinase kinase binding	1/2454	10/18639	0.1	0.759535452322738	0.756363743288886	0.999999999999181
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	1/2454	10/18639	0.1	0.759535452322738	0.756363743288886	0.999999999999181
GO:0035374	chondroitin sulfate binding	1/2454	10/18639	0.1	0.759535452322738	0.756363743288886	0.999999999999181
GO:0043422	protein kinase B binding	1/2454	10/18639	0.1	0.759535452322738	0.756363743288886	0.999999999999181
GO:0140940	histone H2A methyltransferase activity	1/2454	10/18639	0.1	0.759535452322738	0.756363743288886	0.999999999999181
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	1/2454	10/18639	0.1	0.759535452322738	0.756363743288886	0.999999999999181
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	1/2454	10/18639	0.1	0.759535452322738	0.756363743288886	0.999999999999181
GO:1905394	retromer complex binding	1/2454	10/18639	0.1	0.759535452322738	0.756363743288886	0.999999999999181
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	1/2454	10/18639	0.1	0.759535452322738	0.756363743288886	0.999999999999181
GO:1990259	histone H2AQ104 methyltransferase activity	1/2454	10/18639	0.1	0.759535452322738	0.756363743288886	0.999999999999181
GO:1990757	ubiquitin ligase activator activity	1/2454	10/18639	0.1	0.759535452322738	0.756363743288886	0.999999999999181
GO:1990763	arrestin family protein binding	1/2454	10/18639	0.1	0.759535452322738	0.756363743288886	0.999999999999181
GO:0001614	purinergic nucleotide receptor activity	2/2454	20/18639	0.1	0.759535452322738	0.760623516726393	0.999999999999181
GO:0001972	retinoic acid binding	2/2454	20/18639	0.1	0.759535452322738	0.760623516726393	0.999999999999181
GO:0016502	nucleotide receptor activity	2/2454	20/18639	0.1	0.759535452322738	0.760623516726393	0.999999999999181
GO:0031418	L-ascorbic acid binding	2/2454	20/18639	0.1	0.759535452322738	0.760623516726393	0.999999999999181
GO:0140939	histone H4 methyltransferase activity	2/2454	20/18639	0.1	0.759535452322738	0.760623516726393	0.999999999999181
GO:0004521	RNA endonuclease activity	8/2454	73/18639	0.10958904109589	0.832367618983823	0.761753981441054	0.999999999999181
GO:0170055	lipid transmembrane transporter activity	6/2454	56/18639	0.107142857142857	0.813787984631505	0.76381114708233	0.999999999999181
GO:0160215	deacylase activity	7/2454	65/18639	0.107692307692308	0.817961256347564	0.769265616912243	0.999999999999181
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	3/2454	30/18639	0.1	0.759535452322738	0.775113046272781	0.999999999999181
GO:0033612	receptor serine/threonine kinase binding	3/2454	30/18639	0.1	0.759535452322738	0.775113046272781	0.999999999999181
GO:0048019	receptor antagonist activity	3/2454	30/18639	0.1	0.759535452322738	0.775113046272781	0.999999999999181
GO:0001846	opsonin binding	2/2454	21/18639	0.0952380952380952	0.723367097450227	0.784346720589498	0.999999999999181
GO:0015125	bile acid transmembrane transporter activity	2/2454	21/18639	0.0952380952380952	0.723367097450227	0.784346720589498	0.999999999999181
GO:0015174	basic amino acid transmembrane transporter activity	2/2454	21/18639	0.0952380952380952	0.723367097450227	0.784346720589498	0.999999999999181
GO:0000099	sulfur amino acid transmembrane transporter activity	1/2454	11/18639	0.0909090909090909	0.690486774838853	0.78845797131879	0.999999999999181
GO:0005114	type II transforming growth factor beta receptor binding	1/2454	11/18639	0.0909090909090909	0.690486774838853	0.78845797131879	0.999999999999181
GO:0008503	benzodiazepine receptor activity	1/2454	11/18639	0.0909090909090909	0.690486774838853	0.78845797131879	0.999999999999181
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	1/2454	11/18639	0.0909090909090909	0.690486774838853	0.78845797131879	0.999999999999181
GO:0015217	ADP transmembrane transporter activity	1/2454	11/18639	0.0909090909090909	0.690486774838853	0.78845797131879	0.999999999999181
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/2454	11/18639	0.0909090909090909	0.690486774838853	0.78845797131879	0.999999999999181
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/2454	11/18639	0.0909090909090909	0.690486774838853	0.78845797131879	0.999999999999181
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	1/2454	11/18639	0.0909090909090909	0.690486774838853	0.78845797131879	0.999999999999181
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/2454	11/18639	0.0909090909090909	0.690486774838853	0.78845797131879	0.999999999999181
GO:0019107	myristoyltransferase activity	1/2454	11/18639	0.0909090909090909	0.690486774838853	0.78845797131879	0.999999999999181
GO:0019206	nucleoside kinase activity	1/2454	11/18639	0.0909090909090909	0.690486774838853	0.78845797131879	0.999999999999181
GO:0031731	CCR6 chemokine receptor binding	1/2454	11/18639	0.0909090909090909	0.690486774838853	0.78845797131879	0.999999999999181
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	1/2454	11/18639	0.0909090909090909	0.690486774838853	0.78845797131879	0.999999999999181
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/2454	11/18639	0.0909090909090909	0.690486774838853	0.78845797131879	0.999999999999181
GO:0050998	nitric-oxide synthase binding	1/2454	11/18639	0.0909090909090909	0.690486774838853	0.78845797131879	0.999999999999181
GO:0097493	structural molecule activity conferring elasticity	1/2454	11/18639	0.0909090909090909	0.690486774838853	0.78845797131879	0.999999999999181
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/2454	11/18639	0.0909090909090909	0.690486774838853	0.78845797131879	0.999999999999181
GO:0004177	aminopeptidase activity	4/2454	40/18639	0.1	0.759535452322738	0.790574453487221	0.999999999999181
GO:0015144	carbohydrate transmembrane transporter activity	4/2454	40/18639	0.1	0.759535452322738	0.790574453487221	0.999999999999181
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	4/2454	40/18639	0.1	0.759535452322738	0.790574453487221	0.999999999999181
GO:0016878	acid-thiol ligase activity	3/2454	31/18639	0.0967741935483871	0.735034308699424	0.794182074235277	0.999999999999181
GO:0047499	calcium-independent phospholipase A2 activity	3/2454	31/18639	0.0967741935483871	0.735034308699424	0.794182074235277	0.999999999999181
GO:0050840	extracellular matrix binding	7/2454	67/18639	0.104477611940299	0.793544502426742	0.796018334577027	0.999999999999181
GO:0004519	endonuclease activity	14/2454	127/18639	0.110236220472441	0.837283175788845	0.799404523283379	0.999999999999181
GO:0008649	rRNA methyltransferase activity	2/2454	22/18639	0.0909090909090909	0.690486774838853	0.805975508823116	0.999999999999181
GO:0015377	chloride:monoatomic cation symporter activity	2/2454	22/18639	0.0909090909090909	0.690486774838853	0.805975508823116	0.999999999999181
GO:0008194	UDP-glycosyltransferase activity	16/2454	145/18639	0.110344827586207	0.838108085321642	0.810403325444947	0.999999999999181
GO:0042910	xenobiotic transmembrane transporter activity	3/2454	32/18639	0.09375	0.712064486552567	0.811881259658846	0.999999999999181
GO:0047498	calcium-dependent phospholipase A2 activity	3/2454	32/18639	0.09375	0.712064486552567	0.811881259658846	0.999999999999181
GO:0016209	antioxidant activity	9/2454	86/18639	0.104651162790698	0.794862682663331	0.814864741996163	0.999999999999181
GO:0000995	RNA polymerase III general transcription initiation factor activity	1/2454	12/18639	0.0833333333333333	0.632946210268949	0.816325919481968	0.999999999999181
GO:0003720	telomerase activity	1/2454	12/18639	0.0833333333333333	0.632946210268949	0.816325919481968	0.999999999999181
GO:0004526	ribonuclease P activity	1/2454	12/18639	0.0833333333333333	0.632946210268949	0.816325919481968	0.999999999999181
GO:0008179	adenylate cyclase binding	1/2454	12/18639	0.0833333333333333	0.632946210268949	0.816325919481968	0.999999999999181
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	1/2454	12/18639	0.0833333333333333	0.632946210268949	0.816325919481968	0.999999999999181
GO:0015166	polyol transmembrane transporter activity	1/2454	12/18639	0.0833333333333333	0.632946210268949	0.816325919481968	0.999999999999181
GO:0016208	AMP binding	1/2454	12/18639	0.0833333333333333	0.632946210268949	0.816325919481968	0.999999999999181
GO:0016423	tRNA (guanine) methyltransferase activity	1/2454	12/18639	0.0833333333333333	0.632946210268949	0.816325919481968	0.999999999999181
GO:0016801	hydrolase activity, acting on ether bonds	1/2454	12/18639	0.0833333333333333	0.632946210268949	0.816325919481968	0.999999999999181
GO:0016803	ether hydrolase activity	1/2454	12/18639	0.0833333333333333	0.632946210268949	0.816325919481968	0.999999999999181
GO:0016840	carbon-nitrogen lyase activity	1/2454	12/18639	0.0833333333333333	0.632946210268949	0.816325919481968	0.999999999999181
GO:0035251	UDP-glucosyltransferase activity	1/2454	12/18639	0.0833333333333333	0.632946210268949	0.816325919481968	0.999999999999181
GO:0036009	protein-glutamine N-methyltransferase activity	1/2454	12/18639	0.0833333333333333	0.632946210268949	0.816325919481968	0.999999999999181
GO:0045295	gamma-catenin binding	1/2454	12/18639	0.0833333333333333	0.632946210268949	0.816325919481968	0.999999999999181
GO:0097371	MDM2/MDM4 family protein binding	1/2454	12/18639	0.0833333333333333	0.632946210268949	0.816325919481968	0.999999999999181
GO:1990459	transferrin receptor binding	1/2454	12/18639	0.0833333333333333	0.632946210268949	0.816325919481968	0.999999999999181
GO:0003730	mRNA 3'-UTR binding	30/2454	262/18639	0.114503816793893	0.869697082812296	0.820192595188059	0.999999999999181
GO:0004602	glutathione peroxidase activity	2/2454	23/18639	0.0869565217391304	0.660465610715425	0.825649912810054	0.999999999999181
GO:0005283	amino acid:sodium symporter activity	2/2454	23/18639	0.0869565217391304	0.660465610715425	0.825649912810054	0.999999999999181
GO:0008171	O-methyltransferase activity	2/2454	23/18639	0.0869565217391304	0.660465610715425	0.825649912810054	0.999999999999181
GO:0017134	fibroblast growth factor binding	2/2454	23/18639	0.0869565217391304	0.660465610715425	0.825649912810054	0.999999999999181
GO:0031681	G-protein beta-subunit binding	2/2454	23/18639	0.0869565217391304	0.660465610715425	0.825649912810054	0.999999999999181
GO:0099186	structural constituent of postsynapse	2/2454	23/18639	0.0869565217391304	0.660465610715425	0.825649912810054	0.999999999999181
GO:0140102	catalytic activity, acting on a rRNA	2/2454	23/18639	0.0869565217391304	0.660465610715425	0.825649912810054	0.999999999999181
GO:0140103	catalytic activity, acting on a glycoprotein	2/2454	23/18639	0.0869565217391304	0.660465610715425	0.825649912810054	0.999999999999181
GO:0030296	protein tyrosine kinase activator activity	3/2454	33/18639	0.0909090909090909	0.690486774838853	0.828273544409212	0.999999999999181
GO:0070851	growth factor receptor binding	15/2454	139/18639	0.107913669064748	0.819642574448998	0.830316412302144	0.999999999999181
GO:0016836	hydro-lyase activity	6/2454	61/18639	0.0983606557377049	0.747084051464989	0.83111335808848	0.999999999999181
GO:0019905	syntaxin binding	6/2454	61/18639	0.0983606557377049	0.747084051464989	0.83111335808848	0.999999999999181
GO:0008375	acetylglucosaminyltransferase activity	4/2454	43/18639	0.0930232558139535	0.70654460681185	0.835594610189563	0.999999999999181
GO:0002161	aminoacyl-tRNA editing activity	1/2454	13/18639	0.0769230769230769	0.58425804024826	0.840523922036929	0.999999999999181
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/2454	13/18639	0.0769230769230769	0.58425804024826	0.840523922036929	0.999999999999181
GO:0003964	RNA-directed DNA polymerase activity	1/2454	13/18639	0.0769230769230769	0.58425804024826	0.840523922036929	0.999999999999181
GO:0005172	vascular endothelial growth factor receptor binding	1/2454	13/18639	0.0769230769230769	0.58425804024826	0.840523922036929	0.999999999999181
GO:0005338	nucleotide-sugar transmembrane transporter activity	1/2454	13/18639	0.0769230769230769	0.58425804024826	0.840523922036929	0.999999999999181
GO:0008253	5'-nucleotidase activity	1/2454	13/18639	0.0769230769230769	0.58425804024826	0.840523922036929	0.999999999999181
GO:0008417	fucosyltransferase activity	1/2454	13/18639	0.0769230769230769	0.58425804024826	0.840523922036929	0.999999999999181
GO:0009982	pseudouridine synthase activity	1/2454	13/18639	0.0769230769230769	0.58425804024826	0.840523922036929	0.999999999999181
GO:0017154	semaphorin receptor activity	1/2454	13/18639	0.0769230769230769	0.58425804024826	0.840523922036929	0.999999999999181
GO:0031432	titin binding	1/2454	13/18639	0.0769230769230769	0.58425804024826	0.840523922036929	0.999999999999181
GO:0071837	HMG box domain binding	1/2454	13/18639	0.0769230769230769	0.58425804024826	0.840523922036929	0.999999999999181
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/2454	13/18639	0.0769230769230769	0.58425804024826	0.840523922036929	0.999999999999181
GO:0015399	primary active transmembrane transporter activity	18/2454	166/18639	0.108433734939759	0.823592659145138	0.842711452774084	0.999999999999181
GO:0008175	tRNA methyltransferase activity	3/2454	34/18639	0.0882352941176471	0.670178340284769	0.843424697323276	0.999999999999181
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	3/2454	34/18639	0.0882352941176471	0.670178340284769	0.843424697323276	0.999999999999181
GO:0015149	hexose transmembrane transporter activity	2/2454	24/18639	0.0833333333333333	0.632946210268949	0.843509409330721	0.999999999999181
GO:0030215	semaphorin receptor binding	2/2454	24/18639	0.0833333333333333	0.632946210268949	0.843509409330721	0.999999999999181
GO:0055056	D-glucose transmembrane transporter activity	2/2454	24/18639	0.0833333333333333	0.632946210268949	0.843509409330721	0.999999999999181
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/2454	24/18639	0.0833333333333333	0.632946210268949	0.843509409330721	0.999999999999181
GO:0030547	signaling receptor inhibitor activity	4/2454	44/18639	0.0909090909090909	0.690486774838853	0.848680762711511	0.999999999999181
GO:0050661	NADP binding	5/2454	54/18639	0.0925925925925926	0.703273566965498	0.855801779648895	0.999999999999181
GO:0004623	phospholipase A2 activity	3/2454	35/18639	0.0857142857142857	0.651030387705204	0.85740205324559	0.999999999999181
GO:0022804	active transmembrane transporter activity	53/2454	457/18639	0.115973741794311	0.880861684313023	0.859314756811837	0.999999999999181
GO:0001848	complement binding	2/2454	25/18639	0.08	0.607628361858191	0.859690640022017	0.999999999999181
GO:0015296	monoatomic anion:monoatomic cation symporter activity	2/2454	25/18639	0.08	0.607628361858191	0.859690640022017	0.999999999999181
GO:0019706	protein-cysteine S-palmitoyltransferase activity	2/2454	25/18639	0.08	0.607628361858191	0.859690640022017	0.999999999999181
GO:0019707	protein-cysteine S-acyltransferase activity	2/2454	25/18639	0.08	0.607628361858191	0.859690640022017	0.999999999999181
GO:0047617	fatty acyl-CoA hydrolase activity	2/2454	25/18639	0.08	0.607628361858191	0.859690640022017	0.999999999999181
GO:0005313	L-glutamate transmembrane transporter activity	1/2454	14/18639	0.0714285714285714	0.54252532308767	0.861535105077913	0.999999999999181
GO:0005344	oxygen carrier activity	1/2454	14/18639	0.0714285714285714	0.54252532308767	0.861535105077913	0.999999999999181
GO:0005545	1-phosphatidylinositol binding	1/2454	14/18639	0.0714285714285714	0.54252532308767	0.861535105077913	0.999999999999181
GO:0031404	chloride ion binding	1/2454	14/18639	0.0714285714285714	0.54252532308767	0.861535105077913	0.999999999999181
GO:0043176	amine binding	1/2454	14/18639	0.0714285714285714	0.54252532308767	0.861535105077913	0.999999999999181
GO:1901474	azole transmembrane transporter activity	1/2454	14/18639	0.0714285714285714	0.54252532308767	0.861535105077913	0.999999999999181
GO:1901612	cardiolipin binding	1/2454	14/18639	0.0714285714285714	0.54252532308767	0.861535105077913	0.999999999999181
GO:0072341	modified amino acid binding	9/2454	91/18639	0.0989010989010989	0.75118890889062	0.862489025139564	0.999999999999181
GO:0004536	DNA nuclease activity	6/2454	64/18639	0.09375	0.712064486552567	0.863506047560931	0.999999999999181
GO:0004033	aldo-keto reductase (NADPH) activity	3/2454	36/18639	0.0833333333333333	0.632946210268949	0.870273459292937	0.999999999999181
GO:0016409	palmitoyltransferase activity	3/2454	36/18639	0.0833333333333333	0.632946210268949	0.870273459292937	0.999999999999181
GO:0048029	monosaccharide binding	7/2454	74/18639	0.0945945945945946	0.718479481926915	0.871247992043218	0.999999999999181
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	4/2454	46/18639	0.0869565217391304	0.660465610715425	0.872217004942216	0.999999999999181
GO:0019843	rRNA binding	6/2454	65/18639	0.0923076923076923	0.701109648297912	0.873089820169272	0.999999999999181
GO:0038024	cargo receptor activity	6/2454	65/18639	0.0923076923076923	0.701109648297912	0.873089820169272	0.999999999999181
GO:0004435	phosphatidylinositol phospholipase C activity	2/2454	26/18639	0.0769230769230769	0.58425804024826	0.874325740530635	0.999999999999181
GO:0016289	acyl-CoA hydrolase activity	2/2454	26/18639	0.0769230769230769	0.58425804024826	0.874325740530635	0.999999999999181
GO:0030247	polysaccharide binding	2/2454	26/18639	0.0769230769230769	0.58425804024826	0.874325740530635	0.999999999999181
GO:0070006	metalloaminopeptidase activity	2/2454	26/18639	0.0769230769230769	0.58425804024826	0.874325740530635	0.999999999999181
GO:0097602	cullin family protein binding	2/2454	26/18639	0.0769230769230769	0.58425804024826	0.874325740530635	0.999999999999181
GO:0004089	carbonate dehydratase activity	1/2454	15/18639	0.0666666666666667	0.506356968215159	0.879779016602144	0.999999999999181
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/2454	15/18639	0.0666666666666667	0.506356968215159	0.879779016602144	0.999999999999181
GO:0008252	nucleotidase activity	1/2454	15/18639	0.0666666666666667	0.506356968215159	0.879779016602144	0.999999999999181
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/2454	15/18639	0.0666666666666667	0.506356968215159	0.879779016602144	0.999999999999181
GO:0016846	carbon-sulfur lyase activity	1/2454	15/18639	0.0666666666666667	0.506356968215159	0.879779016602144	0.999999999999181
GO:0031005	filamin binding	1/2454	15/18639	0.0666666666666667	0.506356968215159	0.879779016602144	0.999999999999181
GO:0047372	monoacylglycerol lipase activity	1/2454	15/18639	0.0666666666666667	0.506356968215159	0.879779016602144	0.999999999999181
GO:0055105	ubiquitin-protein transferase inhibitor activity	1/2454	15/18639	0.0666666666666667	0.506356968215159	0.879779016602144	0.999999999999181
GO:0022829	wide pore channel activity	3/2454	37/18639	0.0810810810810811	0.615839555937356	0.882106405619056	0.999999999999181
GO:0043394	proteoglycan binding	3/2454	37/18639	0.0810810810810811	0.615839555937356	0.882106405619056	0.999999999999181
GO:0015081	sodium ion transmembrane transporter activity	17/2454	164/18639	0.103658536585366	0.78732333472479	0.88396090776488	0.999999999999181
GO:0042562	hormone binding	9/2454	94/18639	0.0957446808510638	0.72721479477709	0.885985731729429	0.999999999999181
GO:0004364	glutathione transferase activity	2/2454	27/18639	0.0740740740740741	0.562618853572399	0.887541158447821	0.999999999999181
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	2/2454	27/18639	0.0740740740740741	0.562618853572399	0.887541158447821	0.999999999999181
GO:0051536	iron-sulfur cluster binding	7/2454	76/18639	0.0921052631578947	0.699572127139364	0.887970017181242	0.999999999999181
GO:0140101	catalytic activity, acting on a tRNA	14/2454	139/18639	0.100719424460432	0.764999736152398	0.889990996170958	0.999999999999181
GO:0032266	phosphatidylinositol-3-phosphate binding	4/2454	48/18639	0.0833333333333333	0.632946210268949	0.892523019986732	0.999999999999181
GO:0005262	calcium channel activity	13/2454	131/18639	0.099236641221374	0.753737471770656	0.894619260640425	0.999999999999181
GO:0005324	long-chain fatty acid transmembrane transporter activity	1/2454	16/18639	0.0625	0.474709657701711	0.895619990252184	0.999999999999181
GO:0031435	mitogen-activated protein kinase kinase kinase binding	1/2454	16/18639	0.0625	0.474709657701711	0.895619990252184	0.999999999999181
GO:0051540	metal cluster binding	7/2454	77/18639	0.0909090909090909	0.690486774838853	0.895622696911675	0.999999999999181
GO:0061135	endopeptidase regulator activity	19/2454	184/18639	0.103260869565217	0.784302912724567	0.898462812571165	0.999999999999181
GO:0016866	intramolecular transferase activity	2/2454	28/18639	0.0714285714285714	0.54252532308767	0.899456860363926	0.999999999999181
GO:0045499	chemorepellent activity	2/2454	28/18639	0.0714285714285714	0.54252532308767	0.899456860363926	0.999999999999181
GO:0004549	tRNA-specific ribonuclease activity	1/2454	17/18639	0.0588235294117647	0.446785560189846	0.909374409192265	0.999999999999181
GO:0004659	prenyltransferase activity	1/2454	17/18639	0.0588235294117647	0.446785560189846	0.909374409192265	0.999999999999181
GO:0008569	minus-end-directed microtubule motor activity	1/2454	17/18639	0.0588235294117647	0.446785560189846	0.909374409192265	0.999999999999181
GO:0009881	photoreceptor activity	1/2454	17/18639	0.0588235294117647	0.446785560189846	0.909374409192265	0.999999999999181
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/2454	17/18639	0.0588235294117647	0.446785560189846	0.909374409192265	0.999999999999181
GO:0017110	nucleoside diphosphate phosphatase activity	1/2454	17/18639	0.0588235294117647	0.446785560189846	0.909374409192265	0.999999999999181
GO:0030548	acetylcholine receptor regulator activity	1/2454	17/18639	0.0588235294117647	0.446785560189846	0.909374409192265	0.999999999999181
GO:0036041	long-chain fatty acid binding	1/2454	17/18639	0.0588235294117647	0.446785560189846	0.909374409192265	0.999999999999181
GO:0045125	bioactive lipid receptor activity	1/2454	17/18639	0.0588235294117647	0.446785560189846	0.909374409192265	0.999999999999181
GO:0045236	CXCR chemokine receptor binding	1/2454	17/18639	0.0588235294117647	0.446785560189846	0.909374409192265	0.999999999999181
GO:0070402	NADPH binding	1/2454	17/18639	0.0588235294117647	0.446785560189846	0.909374409192265	0.999999999999181
GO:0070492	oligosaccharide binding	1/2454	17/18639	0.0588235294117647	0.446785560189846	0.909374409192265	0.999999999999181
GO:0005416	amino acid:monoatomic cation symporter activity	2/2454	29/18639	0.0689655172413793	0.523817553326026	0.910185846135673	0.999999999999181
GO:0008028	monocarboxylic acid transmembrane transporter activity	6/2454	70/18639	0.0857142857142857	0.651030387705204	0.912927769781303	0.999999999999181
GO:0016782	transferase activity, transferring sulphur-containing groups	6/2454	70/18639	0.0857142857142857	0.651030387705204	0.912927769781303	0.999999999999181
GO:0016597	amino acid binding	4/2454	51/18639	0.0784313725490196	0.595714080253128	0.917669269363625	0.999999999999181
GO:0016758	hexosyltransferase activity	20/2454	197/18639	0.101522842639594	0.771101982053542	0.917686743737307	0.999999999999181
GO:0008106	alcohol dehydrogenase (NADP+) activity	2/2454	30/18639	0.0666666666666667	0.506356968215159	0.919833903268737	0.999999999999181
GO:0098918	structural constituent of synapse	2/2454	30/18639	0.0666666666666667	0.506356968215159	0.919833903268737	0.999999999999181
GO:0008137	NADH dehydrogenase (ubiquinone) activity	3/2454	41/18639	0.0731707317073171	0.555757648041028	0.920355189170607	0.999999999999181
GO:0005372	water transmembrane transporter activity	1/2454	18/18639	0.0555555555555556	0.421964140179299	0.921317014704143	0.999999999999181
GO:0015172	acidic amino acid transmembrane transporter activity	1/2454	18/18639	0.0555555555555556	0.421964140179299	0.921317014704143	0.999999999999181
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	1/2454	18/18639	0.0555555555555556	0.421964140179299	0.921317014704143	0.999999999999181
GO:0016854	racemase and epimerase activity	1/2454	18/18639	0.0555555555555556	0.421964140179299	0.921317014704143	0.999999999999181
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/2454	18/18639	0.0555555555555556	0.421964140179299	0.921317014704143	0.999999999999181
GO:0017075	syntaxin-1 binding	1/2454	18/18639	0.0555555555555556	0.421964140179299	0.921317014704143	0.999999999999181
GO:0017128	phospholipid scramblase activity	1/2454	18/18639	0.0555555555555556	0.421964140179299	0.921317014704143	0.999999999999181
GO:0004520	DNA endonuclease activity	3/2454	42/18639	0.0714285714285714	0.54252532308767	0.927953720300537	0.999999999999181
GO:0042056	chemoattractant activity	3/2454	42/18639	0.0714285714285714	0.54252532308767	0.927953720300537	0.999999999999181
GO:0005310	dicarboxylic acid transmembrane transporter activity	2/2454	31/18639	0.0645161290322581	0.490022872466283	0.928499546650355	0.999999999999181
GO:0008514	organic anion transmembrane transporter activity	28/2454	269/18639	0.104089219330855	0.790594522863817	0.928507174428317	0.999999999999181
GO:0005507	copper ion binding	5/2454	63/18639	0.0793650793650794	0.602805914541856	0.930517429730926	0.999999999999181
GO:1901682	sulfur compound transmembrane transporter activity	5/2454	63/18639	0.0793650793650794	0.602805914541856	0.930517429730926	0.999999999999181
GO:0015245	fatty acid transmembrane transporter activity	1/2454	19/18639	0.0526315789473684	0.399755501222494	0.931686385087905	0.999999999999181
GO:0034987	immunoglobulin receptor binding	1/2454	19/18639	0.0526315789473684	0.399755501222494	0.931686385087905	0.999999999999181
GO:0042834	peptidoglycan binding	1/2454	19/18639	0.0526315789473684	0.399755501222494	0.931686385087905	0.999999999999181
GO:0046527	glucosyltransferase activity	1/2454	19/18639	0.0526315789473684	0.399755501222494	0.931686385087905	0.999999999999181
GO:0015171	amino acid transmembrane transporter activity	9/2454	102/18639	0.0882352941176471	0.670178340284769	0.932886273912677	0.999999999999181
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	3/2454	43/18639	0.0697674418604651	0.529908455108887	0.93488065355886	0.999999999999181
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/2454	20/18639	0.05	0.379767726161369	0.940689693949037	0.999999999999181
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/2454	20/18639	0.05	0.379767726161369	0.940689693949037	0.999999999999181
GO:0003954	NADH dehydrogenase activity	3/2454	44/18639	0.0681818181818182	0.51786508112914	0.941187962645251	0.999999999999181
GO:0016790	thiolester hydrolase activity	3/2454	44/18639	0.0681818181818182	0.51786508112914	0.941187962645251	0.999999999999181
GO:0046943	carboxylic acid transmembrane transporter activity	18/2454	188/18639	0.0957446808510638	0.72721479477709	0.94720917123769	0.999999999999181
GO:0030170	pyridoxal phosphate binding	4/2454	56/18639	0.0714285714285714	0.54252532308767	0.948073460700072	0.999999999999181
GO:0061891	calcium ion sensor activity	1/2454	21/18639	0.0476190476190476	0.361683548725113	0.948506842617014	0.999999999999181
GO:0005342	organic acid transmembrane transporter activity	18/2454	189/18639	0.0952380952380952	0.723367097450227	0.950019692455361	0.999999999999181
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	5/2454	67/18639	0.0746268656716418	0.566817501733387	0.950815976960934	0.999999999999181
GO:0004601	peroxidase activity	4/2454	57/18639	0.0701754385964912	0.533007334963325	0.952754287140767	0.999999999999181
GO:0070279	vitamin B6 binding	4/2454	57/18639	0.0701754385964912	0.533007334963325	0.952754287140767	0.999999999999181
GO:0005243	gap junction channel activity	1/2454	22/18639	0.0454545454545455	0.345243387419427	0.955294048988152	0.999999999999181
GO:0033691	sialic acid binding	1/2454	22/18639	0.0454545454545455	0.345243387419427	0.955294048988152	0.999999999999181
GO:0140784	metal ion sensor activity	1/2454	22/18639	0.0454545454545455	0.345243387419427	0.955294048988152	0.999999999999181
GO:0030246	carbohydrate binding	28/2454	280/18639	0.1	0.759535452322738	0.956529128525307	0.999999999999181
GO:0022853	active monoatomic ion transmembrane transporter activity	10/2454	118/18639	0.0847457627118644	0.643674112137914	0.957397050732832	0.999999999999181
GO:0004620	phospholipase activity	9/2454	109/18639	0.0825688073394495	0.627139364303179	0.95915794322592	0.999999999999181
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	4/2454	59/18639	0.0677966101694915	0.514939289710331	0.96097067908646	0.999999999999181
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/2454	23/18639	0.0434782608695652	0.330232805357712	0.961186964268975	0.999999999999181
GO:0016917	GABA receptor activity	1/2454	23/18639	0.0434782608695652	0.330232805357712	0.961186964268975	0.999999999999181
GO:0140299	molecular sensor activity	5/2454	71/18639	0.0704225352112676	0.534884121354041	0.965572351617163	0.999999999999181
GO:0004622	lysophospholipase activity	1/2454	24/18639	0.0416666666666667	0.316473105134474	0.966303379701073	0.999999999999181
GO:0004806	triacylglycerol lipase activity	1/2454	24/18639	0.0416666666666667	0.316473105134474	0.966303379701073	0.999999999999181
GO:0005540	hyaluronic acid binding	1/2454	24/18639	0.0416666666666667	0.316473105134474	0.966303379701073	0.999999999999181
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/2454	24/18639	0.0416666666666667	0.316473105134474	0.966303379701073	0.999999999999181
GO:0140612	DNA damage sensor activity	1/2454	24/18639	0.0416666666666667	0.316473105134474	0.966303379701073	0.999999999999181
GO:0052689	carboxylic ester hydrolase activity	7/2454	92/18639	0.0760869565217391	0.577907409375997	0.966838808065386	0.999999999999181
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	4/2454	61/18639	0.0655737704918033	0.498056034309992	0.967844702980147	0.999999999999181
GO:0005501	retinoid binding	2/2454	38/18639	0.0526315789473684	0.399755501222494	0.968476456266657	0.999999999999181
GO:0019840	isoprenoid binding	2/2454	38/18639	0.0526315789473684	0.399755501222494	0.968476456266657	0.999999999999181
GO:0005537	D-mannose binding	1/2454	25/18639	0.04	0.303814180929095	0.9707455771877	0.999999999999181
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/2454	25/18639	0.04	0.303814180929095	0.9707455771877	0.999999999999181
GO:0008198	ferrous iron binding	1/2454	26/18639	0.0384615384615385	0.29212902012413	0.974602370653983	0.999999999999181
GO:0019865	immunoglobulin binding	1/2454	26/18639	0.0384615384615385	0.29212902012413	0.974602370653983	0.999999999999181
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	3/2454	52/18639	0.0576923076923077	0.438193530186195	0.974615173844032	0.999999999999181
GO:0071855	neuropeptide receptor binding	2/2454	40/18639	0.05	0.379767726161369	0.975177353220091	0.999999999999181
GO:0033218	amide binding	23/2454	247/18639	0.0931174089068826	0.707259732932105	0.975502185022574	0.999999999999181
GO:0015103	inorganic anion transmembrane transporter activity	14/2454	165/18639	0.0848484848484849	0.64445432318293	0.976885543664297	0.999999999999181
GO:0008146	sulfotransferase activity	3/2454	53/18639	0.0566037735849057	0.429925727729852	0.977209991778605	0.999999999999181
GO:0017080	sodium channel regulator activity	2/2454	41/18639	0.0487804878048781	0.370505098694019	0.977988746248269	0.999999999999181
GO:0016651	oxidoreductase activity, acting on NAD(P)H	6/2454	88/18639	0.0681818181818182	0.51786508112914	0.980662979086241	0.999999999999181
GO:0051393	alpha-actinin binding	1/2454	28/18639	0.0357142857142857	0.271262661543835	0.980858064684344	0.999999999999181
GO:0051537	2 iron, 2 sulfur cluster binding	1/2454	28/18639	0.0357142857142857	0.271262661543835	0.980858064684344	0.999999999999181
GO:0016798	hydrolase activity, acting on glycosyl bonds	10/2454	130/18639	0.0769230769230769	0.58425804024826	0.982269818800414	0.999999999999181
GO:0019842	vitamin binding	12/2454	150/18639	0.08	0.607628361858191	0.982682817021115	0.999999999999181
GO:0004181	metallocarboxypeptidase activity	1/2454	29/18639	0.0344827586206897	0.261908776663013	0.983382072489654	0.999999999999181
GO:0051861	glycolipid binding	1/2454	29/18639	0.0344827586206897	0.261908776663013	0.983382072489654	0.999999999999181
GO:0033293	monocarboxylic acid binding	5/2454	79/18639	0.0632911392405063	0.480718640710594	0.983624748696004	0.999999999999181
GO:0004866	endopeptidase inhibitor activity	13/2454	161/18639	0.0807453416149068	0.613289495664323	0.984187179618971	0.999999999999181
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	3/2454	58/18639	0.0517241379310345	0.39286316499452	0.986813978536134	0.999999999999181
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	2/2454	46/18639	0.0434782608695652	0.330232805357712	0.988009191704037	0.999999999999181
GO:0001664	G protein-coupled receptor binding	27/2454	297/18639	0.0909090909090909	0.690486774838853	0.988476609522998	0.999999999999181
GO:0019838	growth factor binding	10/2454	136/18639	0.0735294117647059	0.558481950237308	0.988853389833716	0.999999999999181
GO:0005504	fatty acid binding	2/2454	47/18639	0.0425531914893617	0.323206575456484	0.989393262888357	0.999999999999181
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	1/2454	33/18639	0.0303030303030303	0.230162258279618	0.990561445787703	0.999999999999181
GO:0042923	neuropeptide binding	1/2454	33/18639	0.0303030303030303	0.230162258279618	0.990561445787703	0.999999999999181
GO:0038187	pattern recognition receptor activity	2/2454	48/18639	0.0416666666666667	0.316473105134474	0.99062091657648	0.999999999999181
GO:0030414	peptidase inhibitor activity	13/2454	169/18639	0.0769230769230769	0.58425804024826	0.991092277458563	0.999999999999181
GO:0015020	glucuronosyltransferase activity	1/2454	34/18639	0.0294117647058824	0.223392780094923	0.991806324430988	0.999999999999181
GO:0019825	oxygen binding	1/2454	34/18639	0.0294117647058824	0.223392780094923	0.991806324430988	0.999999999999181
GO:0016298	lipase activity	9/2454	130/18639	0.0692307692307692	0.525832236223434	0.992120693593492	0.999999999999181
GO:0004222	metalloendopeptidase activity	7/2454	110/18639	0.0636363636363636	0.483340742387197	0.992952682650675	0.999999999999181
GO:0008235	metalloexopeptidase activity	3/2454	66/18639	0.0454545454545455	0.345243387419427	0.994637298824982	0.999999999999181
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	5/2454	91/18639	0.0549450549450549	0.4173271716059	0.994953175675646	0.999999999999181
GO:0017046	peptide hormone binding	2/2454	53/18639	0.0377358490566038	0.286617151819901	0.994954382358837	0.999999999999181
GO:0005253	monoatomic anion channel activity	6/2454	103/18639	0.058252427184466	0.442447836304508	0.995192653073101	0.999999999999181
GO:0005109	frizzled binding	1/2454	38/18639	0.0263157894736842	0.199877750611247	0.995346963581298	0.999999999999181
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	3/2454	68/18639	0.0441176470588235	0.335089170142385	0.995734733386652	0.999999999999181
GO:0009055	electron transfer activity	7/2454	116/18639	0.0603448275862069	0.458340359160273	0.99593294749781	0.999999999999181
GO:0008509	monoatomic anion transmembrane transporter activity	10/2454	149/18639	0.0671140939597315	0.509755337129355	0.996128444335068	0.999999999999181
GO:0004497	monooxygenase activity	6/2454	106/18639	0.0566037735849057	0.429925727729852	0.996404094627193	0.999999999999181
GO:0004812	aminoacyl-tRNA ligase activity	1/2454	41/18639	0.024390243902439	0.185252549347009	0.996956365746352	0.999999999999181
GO:0016875	ligase activity, forming carbon-oxygen bonds	1/2454	41/18639	0.024390243902439	0.185252549347009	0.996956365746352	0.999999999999181
GO:0005245	voltage-gated calcium channel activity	1/2454	43/18639	0.0232558139534884	0.176636151702962	0.997706605723637	0.999999999999181
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	2/2454	60/18639	0.0333333333333333	0.253178484107579	0.997906980521763	0.999999999999181
GO:0030020	extracellular matrix structural constituent conferring tensile strength	1/2454	44/18639	0.0227272727272727	0.172621693709713	0.998009250892178	0.999999999999181
GO:0046873	metal ion transmembrane transporter activity	40/2454	450/18639	0.0888888888888889	0.675142624286879	0.998252061794355	0.999999999999181
GO:0008238	exopeptidase activity	5/2454	102/18639	0.0490196078431373	0.372321300158205	0.998373527575047	0.999999999999181
GO:0004180	carboxypeptidase activity	1/2454	46/18639	0.0217391304347826	0.165116402678856	0.998500033746459	0.999999999999181
GO:0008188	neuropeptide receptor activity	1/2454	48/18639	0.0208333333333333	0.158236552567237	0.99886986001427	0.999999999999181
GO:0016879	ligase activity, forming carbon-nitrogen bonds	1/2454	48/18639	0.0208333333333333	0.158236552567237	0.99886986001427	0.999999999999181
GO:0003735	structural constituent of ribosome	11/2454	175/18639	0.0628571428571429	0.47742228431715	0.99895061469183	0.999999999999181
GO:0031406	carboxylic acid binding	12/2454	187/18639	0.0641711229946524	0.487402429298014	0.999055338505064	0.999999999999181
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	7/2454	132/18639	0.053030303030303	0.402783951989331	0.99912155653955	0.999999999999181
GO:0043177	organic acid binding	12/2454	189/18639	0.0634920634920635	0.482244731633485	0.999203238202764	0.999999999999181
GO:0005010	insulin-like growth factor receptor activity	1/2454	51/18639	0.0196078431372549	0.148928520063282	0.999260936546684	0.999999999999181
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	6/2454	122/18639	0.0491803278688525	0.373542025732494	0.999277126466716	0.999999999999181
GO:0005125	cytokine activity	16/2454	234/18639	0.0683760683760684	0.519340480220676	0.999364087980209	0.999999999999181
GO:0008236	serine-type peptidase activity	12/2454	194/18639	0.0618556701030928	0.469815743704787	0.9994820797894	0.999999999999181
GO:0008237	metallopeptidase activity	11/2454	184/18639	0.0597826086956522	0.454070107366854	0.999524524557655	0.999999999999181
GO:0015078	proton transmembrane transporter activity	11/2454	185/18639	0.0594594594594595	0.451615674354061	0.999565187202451	0.999999999999181
GO:0017171	serine hydrolase activity	12/2454	198/18639	0.0606060606060606	0.460324516559235	0.999634887857363	0.999999999999181
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	1/2454	56/18639	0.0178571428571429	0.135631330771918	0.999635923097597	0.999999999999181
GO:0016874	ligase activity	9/2454	167/18639	0.0538922155688623	0.409330483287703	0.99971726303948	0.999999999999181
GO:0004714	transmembrane receptor protein tyrosine kinase activity	1/2454	60/18639	0.0166666666666667	0.12658924205379	0.999793396226228	0.999999999999181
GO:0004867	serine-type endopeptidase inhibitor activity	3/2454	95/18639	0.0315789473684211	0.239853300733496	0.999827683180273	0.999999999999181
GO:0004252	serine-type endopeptidase activity	9/2454	176/18639	0.0511363636363636	0.388398810846855	0.999881804808182	0.999999999999181
GO:0016500	protein-hormone receptor activity	1/2454	67/18639	0.0149253731343284	0.113363500346677	0.999923368867273	0.999999999999181
GO:0098960	postsynaptic neurotransmitter receptor activity	1/2454	69/18639	0.0144927536231884	0.110077601785904	0.999942282616168	0.999999999999181
GO:0015079	potassium ion transmembrane transporter activity	7/2454	160/18639	0.04375	0.332296760391198	0.999950102728387	0.999999999999181
GO:0046906	tetrapyrrole binding	6/2454	152/18639	0.0394736842105263	0.29981662591687	0.99997077937977	0.999999999999181
GO:0005506	iron ion binding	6/2454	154/18639	0.038961038961039	0.295922903502366	0.999976581376464	0.999999999999181
GO:1901681	sulfur compound binding	16/2454	275/18639	0.0581818181818182	0.441911535896866	0.999979788991884	0.999999999999181
GO:0030594	neurotransmitter receptor activity	2/2454	97/18639	0.0206185567010309	0.156605247901596	0.999982822862586	0.999999999999181
GO:0019199	transmembrane receptor protein kinase activity	1/2454	78/18639	0.0128205128205128	0.0973763400413767	0.999983886622233	0.999999999999181
GO:0005254	chloride channel activity	1/2454	83/18639	0.0120481927710843	0.0915102954605709	0.999992071019061	0.999999999999181
GO:0015108	chloride transmembrane transporter activity	3/2454	121/18639	0.0247933884297521	0.188314574956051	0.999993211811548	0.999999999999181
GO:0005539	glycosaminoglycan binding	12/2454	242/18639	0.0495867768595041	0.376629149912102	0.999993947483849	0.999999999999181
GO:0008528	G protein-coupled peptide receptor activity	3/2454	122/18639	0.0245901639344262	0.186771012866247	0.999994017895402	0.999999999999181
GO:0005201	extracellular matrix structural constituent	6/2454	168/18639	0.0357142857142857	0.271262661543835	0.999995132632712	0.999999999999181
GO:0020037	heme binding	4/2454	142/18639	0.028169014084507	0.213953648541616	0.999996507507821	0.999999999999181
GO:0008201	heparin binding	6/2454	172/18639	0.0348837209302326	0.264954227554444	0.999996912799945	0.999999999999181
GO:0001653	peptide receptor activity	3/2454	128/18639	0.0234375	0.178016121638142	0.999997205491658	0.999999999999181
GO:0099094	ligand-gated monoatomic cation channel activity	3/2454	136/18639	0.0220588235294118	0.167544585071192	0.999998993732204	0.999999999999181
GO:0005249	voltage-gated potassium channel activity	1/2454	98/18639	0.0102040816326531	0.0775036175839529	0.999999056429156	0.999999999999181
GO:0005244	voltage-gated monoatomic ion channel activity	5/2454	173/18639	0.0289017341040462	0.219518916856283	0.999999490818551	0.999999999999181
GO:0022832	voltage-gated channel activity	5/2454	175/18639	0.0285714285714286	0.217010129235068	0.999999599563387	0.999999999999181
GO:0008083	growth factor activity	4/2454	162/18639	0.0246913580246914	0.187539617857466	0.999999703084594	0.999999999999181
GO:0005179	hormone activity	2/2454	132/18639	0.0151515151515152	0.115081129139809	0.999999840681976	0.999999999999181
GO:0022843	voltage-gated monoatomic cation channel activity	2/2454	143/18639	0.013986013986014	0.106228734590593	0.999999964028718	0.999999999999181
GO:0005267	potassium channel activity	1/2454	124/18639	0.00806451612903226	0.0612528590582854	0.999999976530616	0.999999999999181
GO:0015276	ligand-gated monoatomic ion channel activity	4/2454	186/18639	0.021505376344086	0.163340957488761	0.999999985475809	0.999999999999181
GO:0005216	monoatomic ion channel activity	24/2454	448/18639	0.0535714285714286	0.406893992315753	0.999999988580166	0.999999999999181
GO:0022834	ligand-gated channel activity	4/2454	188/18639	0.0212765957446809	0.161603287728242	0.999999988733344	0.999999999999181
GO:0005261	monoatomic cation channel activity	14/2454	341/18639	0.0410557184750733	0.311832737023998	0.999999996870512	0.999999999999181
GO:0022836	gated channel activity	11/2454	318/18639	0.0345911949685535	0.262732389168243	0.999999999487824	0.999999999999181
GO:0045182	translation regulator activity	13/2454	356/18639	0.0365168539325843	0.277358451690888	0.999999999847864	0.999999999999181
GO:0030371	translation repressor activity	8/2454	329/18639	0.0243161094224924	0.18468947168942	0.999999999999181	0.999999999999181