ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003712 transcription coregulator activity 174/3194 495/18639 0.351515151515152 2.05131211931462 9.74033986613245e-23 1.28767293030271e-19 GO:0140297 DNA-binding transcription factor binding 163/3194 488/18639 0.334016393442623 1.9491958539064 7.47032001502818e-19 4.93788152993363e-16 GO:0016922 nuclear receptor binding 64/3194 137/18639 0.467153284671533 2.72613339793134 8.64410772625252e-16 3.78375390599719e-13 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 121/3194 349/18639 0.346704871060172 2.02324110572653 1.14485746021095e-15 3.78375390599719e-13 GO:0004674 protein serine/threonine kinase activity 141/3194 433/18639 0.325635103926097 1.90028575519052 1.92912568895944e-15 5.10060832160877e-13 GO:0106310 protein serine kinase activity 120/3194 361/18639 0.332409972299169 1.93982137560558 4.79879316096625e-14 1.0573340931329e-11 GO:0044389 ubiquitin-like protein ligase binding 109/3194 322/18639 0.338509316770186 1.97541488894161 1.83077072286278e-13 3.4575412794637e-11 GO:0031625 ubiquitin protein ligase binding 102/3194 302/18639 0.337748344370861 1.97097413610785 1.27732886876142e-12 2.11078595562824e-10 GO:0003713 transcription coactivator activity 88/3194 256/18639 0.34375 2.00599757357545 1.52256586640765e-11 2.23648008376768e-09 GO:0019787 ubiquitin-like protein transferase activity 140/3194 479/18639 0.292275574112735 1.70561190541242 2.35254703268714e-11 3.1100671772124e-09 GO:0016755 aminoacyltransferase activity 143/3194 496/18639 0.288306451612903 1.68244957783748 4.24499643087586e-11 5.1017138923799e-09 GO:0140996 histone H3 kinase activity 109/3194 357/18639 0.305322128851541 1.78174676257479 2.4410724256788e-10 2.68924812228948e-08 GO:0043130 ubiquitin binding 44/3194 100/18639 0.44 2.56767689417658 3.03996443361953e-10 2.92772750211526e-08 GO:0141003 histone H2AX kinase activity 108/3194 354/18639 0.305084745762712 1.78036148286512 3.10046785397985e-10 2.92772750211526e-08 GO:0035173 histone kinase activity 109/3194 360/18639 0.302777777777778 1.76689887288666 4.19377361090267e-10 3.69611247574222e-08 GO:0004842 ubiquitin-protein transferase activity 129/3194 449/18639 0.287305122494432 1.67660619228983 4.8954482786004e-10 4.04486414019358e-08 GO:0032182 ubiquitin-like protein binding 49/3194 120/18639 0.408333333333333 2.3828819661866 7.24403551415896e-10 5.63330291159891e-08 GO:0140857 histone H3T45 kinase activity 81/3194 246/18639 0.329268292682927 1.92148769797028 1.02932250163061e-09 6.67250390656814e-08 GO:0035402 histone H3T11 kinase activity 81/3194 247/18639 0.327935222672065 1.91370839554935 1.27760613983623e-09 6.67250390656814e-08 GO:0035403 histone H3T6 kinase activity 81/3194 247/18639 0.327935222672065 1.91370839554935 1.27760613983623e-09 6.67250390656814e-08 GO:0042393 histone binding 81/3194 247/18639 0.327935222672065 1.91370839554935 1.27760613983623e-09 6.67250390656814e-08 GO:0004679 AMP-activated protein kinase activity 81/3194 248/18639 0.326612903225806 1.90599182943826 1.5826726650865e-09 6.67250390656814e-08 GO:0045296 cadherin binding 101/3194 334/18639 0.302395209580838 1.76466634670546 1.96904151754054e-09 6.67250390656814e-08 GO:0004676 3-phosphoinositide-dependent protein kinase activity 80/3194 245/18639 0.326530612244898 1.90551160977854 2.01891192331865e-09 6.67250390656814e-08 GO:0004711 ribosomal protein S6 kinase activity 80/3194 245/18639 0.326530612244898 1.90551160977854 2.01891192331865e-09 6.67250390656814e-08 GO:0035175 histone H3S10 kinase activity 80/3194 245/18639 0.326530612244898 1.90551160977854 2.01891192331865e-09 6.67250390656814e-08 GO:0035979 histone H2AXS139 kinase activity 80/3194 245/18639 0.326530612244898 1.90551160977854 2.01891192331865e-09 6.67250390656814e-08 GO:0044022 histone H3S28 kinase activity 80/3194 245/18639 0.326530612244898 1.90551160977854 2.01891192331865e-09 6.67250390656814e-08 GO:0044023 histone H4S1 kinase activity 80/3194 245/18639 0.326530612244898 1.90551160977854 2.01891192331865e-09 6.67250390656814e-08 GO:0044024 histone H2AS1 kinase activity 80/3194 245/18639 0.326530612244898 1.90551160977854 2.01891192331865e-09 6.67250390656814e-08 GO:0044025 histone H2BS14 kinase activity 80/3194 245/18639 0.326530612244898 1.90551160977854 2.01891192331865e-09 6.67250390656814e-08 GO:0072354 histone H3T3 kinase activity 80/3194 245/18639 0.326530612244898 1.90551160977854 2.01891192331865e-09 6.67250390656814e-08 GO:0072371 histone H2AS121 kinase activity 80/3194 245/18639 0.326530612244898 1.90551160977854 2.01891192331865e-09 6.67250390656814e-08 GO:0072518 Rho-dependent protein serine/threonine kinase activity 80/3194 245/18639 0.326530612244898 1.90551160977854 2.01891192331865e-09 6.67250390656814e-08 GO:0140823 histone H2BS36 kinase activity 80/3194 245/18639 0.326530612244898 1.90551160977854 2.01891192331865e-09 6.67250390656814e-08 GO:0140855 histone H3S57 kinase activity 80/3194 245/18639 0.326530612244898 1.90551160977854 2.01891192331865e-09 6.67250390656814e-08 GO:0140995 histone H2A kinase activity 80/3194 245/18639 0.326530612244898 1.90551160977854 2.01891192331865e-09 6.67250390656814e-08 GO:0140997 histone H4 kinase activity 80/3194 245/18639 0.326530612244898 1.90551160977854 2.01891192331865e-09 6.67250390656814e-08 GO:0140998 histone H2B kinase activity 80/3194 245/18639 0.326530612244898 1.90551160977854 2.01891192331865e-09 6.67250390656814e-08 GO:1990244 histone H2AT120 kinase activity 80/3194 245/18639 0.326530612244898 1.90551160977854 2.01891192331865e-09 6.67250390656814e-08 GO:0004677 DNA-dependent protein kinase activity 80/3194 246/18639 0.32520325203252 1.89776562762497 2.49582248798758e-09 8.04750568077945e-08 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 79/3194 243/18639 0.325102880658436 1.89717989749298 3.18327185300308e-09 1.00197271182621e-07 GO:0140030 modification-dependent protein binding 61/3194 173/18639 0.352601156069364 2.05764963931649 6.46556220382695e-09 1.9877844728975e-07 GO:0061659 ubiquitin-like protein ligase activity 108/3194 372/18639 0.290322580645161 1.69421495950068 6.75555710917437e-09 2.02973784052921e-07 GO:0019209 kinase activator activity 54/3194 148/18639 0.364864864864865 2.12921609775085 1.2140980927623e-08 3.56675039695947e-07 GO:0003714 transcription corepressor activity 68/3194 204/18639 0.333333333333333 1.94520976831559 1.26305529095508e-08 3.62991107531004e-07 GO:0019902 phosphatase binding 64/3194 190/18639 0.336842105263158 1.96568566061365 2.1303768615196e-08 5.99225151261471e-07 GO:0003924 GTPase activity 96/3194 331/18639 0.290030211480363 1.69250880143471 4.8495690477123e-08 1.32654981996572e-06 GO:0003725 double-stranded RNA binding 33/3194 75/18639 0.44 2.56767689417658 4.91686393179429e-08 1.32654981996572e-06 GO:0019903 protein phosphatase binding 51/3194 144/18639 0.354166666666667 2.06678537883532 9.28128771839973e-08 2.45397247274489e-06 GO:0003925 G protein activity 26/3194 54/18639 0.481481481481481 2.80974744312252 1.41221677769418e-07 3.66068741198374e-06 GO:0001221 transcription coregulator binding 43/3194 115/18639 0.373913043478261 2.18201791402358 1.62171247609446e-07 4.12289210268631e-06 GO:0061630 ubiquitin protein ligase activity 99/3194 353/18639 0.280453257790368 1.63662124982927 1.80673083480124e-07 4.5066003086929e-06 GO:0030295 protein kinase activator activity 49/3194 139/18639 0.352517985611511 2.05716428735534 1.93862196996739e-07 4.74603378573499e-06 GO:0019207 kinase regulator activity 84/3194 287/18639 0.292682926829268 1.70798906486247 2.13402337792008e-07 5.12941619201881e-06 GO:0140375 immune receptor activity 53/3194 156/18639 0.33974358974359 1.98261764847551 2.4666517415518e-07 5.82306000416336e-06 GO:0005543 phospholipid binding 129/3194 497/18639 0.259557344064386 1.51468044333629 3.50517511994343e-07 8.12954650625476e-06 GO:0030695 GTPase regulator activity 126/3194 489/18639 0.257668711656442 1.50365908471021 7.26547768680117e-07 1.65602784516399e-05 GO:0046332 SMAD binding 32/3194 79/18639 0.40506329113924 2.36379921213034 7.72219598426944e-07 1.73029543918715e-05 GO:0060589 nucleoside-triphosphatase regulator activity 126/3194 490/18639 0.257142857142857 1.5005903927006 8.15728209463716e-07 1.79732115485172e-05 GO:0005525 GTP binding 102/3194 378/18639 0.26984126984127 1.57469362196976 8.74140937518249e-07 1.89444970393299e-05 GO:0042605 peptide antigen binding 22/3194 45/18639 0.488888888888889 2.85297432686287 9.23075433104076e-07 1.96823503639288e-05 GO:0035259 nuclear glucocorticoid receptor binding 10/3194 12/18639 0.833333333333333 4.86302442078898 1.0163276718052e-06 2.13267489226424e-05 GO:0042277 peptide binding 73/3194 249/18639 0.293172690763052 1.71084714562697 1.21044675660576e-06 2.50032908161378e-05 GO:0001222 transcription corepressor binding 23/3194 49/18639 0.469387755102041 2.73917293905665 1.30066432089854e-06 2.64535112650441e-05 GO:0061791 GTPase motor activity 20/3194 40/18639 0.5 2.91781465247339 1.83814372273719e-06 3.62690447978891e-05 GO:1990606 membrane scission GTPase motor activity 20/3194 40/18639 0.5 2.91781465247339 1.83814372273719e-06 3.62690447978891e-05 GO:0023023 MHC protein complex binding 19/3194 37/18639 0.513513513513513 2.99667450794564 1.98146848232114e-06 3.8522078435714e-05 GO:0035091 phosphatidylinositol binding 80/3194 284/18639 0.28169014084507 1.64383924083008 2.18806451265552e-06 4.18942640543688e-05 GO:0035591 signaling adaptor activity 44/3194 129/18639 0.341085271317829 1.99044720478805 2.21830445068518e-06 4.18942640543688e-05 GO:0019001 guanyl nucleotide binding 105/3194 400/18639 0.2625 1.53185269254853 2.43374364715581e-06 4.46862375213885e-05 GO:0032561 guanyl ribonucleotide binding 105/3194 400/18639 0.2625 1.53185269254853 2.43374364715581e-06 4.46862375213885e-05 GO:0019887 protein kinase regulator activity 73/3194 255/18639 0.286274509803922 1.67059191867104 3.16989917948094e-06 5.73478480868186e-05 GO:0061980 regulatory RNA binding 25/3194 58/18639 0.431034482758621 2.51535745902878 3.21009134525308e-06 5.73478480868186e-05 GO:0031072 heat shock protein binding 44/3194 131/18639 0.33587786259542 1.96005869784472 3.5267118618619e-06 6.21641744184191e-05 GO:0002020 protease binding 45/3194 136/18639 0.330882352941176 1.93090675531327 4.3223619261608e-06 7.51863482419023e-05 GO:0032452 histone demethylase activity 16/3194 30/18639 0.533333333333333 3.11233562930495 6.79544841010949e-06 0.000115186078738958 GO:0023026 MHC class II protein complex binding 15/3194 27/18639 0.555555555555556 3.24201628052599 6.79615290592946e-06 0.000115186078738958 GO:0019003 GDP binding 29/3194 75/18639 0.386666666666667 2.25644333124609 7.51459707960307e-06 0.000125750599230826 GO:0000287 magnesium ion binding 66/3194 230/18639 0.28695652173913 1.67457188750647 8.43597611944274e-06 0.000139404505373791 GO:0140457 protein demethylase activity 16/3194 31/18639 0.516129032258065 3.01193770577898 1.18105685457246e-05 0.000191573721813394 GO:0042974 nuclear retinoic acid receptor binding 14/3194 25/18639 0.56 3.26795241077019 1.22510772790647e-05 0.000191573721813394 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 14/3194 25/18639 0.56 3.26795241077019 1.22510772790647e-05 0.000191573721813394 GO:0046966 nuclear thyroid hormone receptor binding 15/3194 28/18639 0.535714285714286 3.12622998479292 1.23175237172001e-05 0.000191573721813394 GO:0141052 histone H3 demethylase activity 15/3194 28/18639 0.535714285714286 3.12622998479292 1.23175237172001e-05 0.000191573721813394 GO:0051020 GTPase binding 84/3194 315/18639 0.266666666666667 1.55616781465247 1.2673216006868e-05 0.00019481385536139 GO:0031267 small GTPase binding 77/3194 283/18639 0.27208480565371 1.58778606530354 1.33240703455375e-05 0.000202464609158628 GO:0140313 molecular sequestering activity 23/3194 55/18639 0.418181818181818 2.44035407297774 1.44593826270205e-05 0.00021721936173774 GO:0031593 polyubiquitin modification-dependent protein binding 24/3194 59/18639 0.406779661016949 2.37381531048682 1.66165198058795e-05 0.000246820664981716 GO:0035198 miRNA binding 19/3194 42/18639 0.452380952380952 2.63992754271402 2.09126171313935e-05 0.000307183109418914 GO:0019783 ubiquitin-like protein peptidase activity 41/3194 127/18639 0.322834645669291 1.88394331891983 2.19595284129232e-05 0.000319016445734995 GO:0032395 MHC class II receptor activity 8/3194 10/18639 0.8 4.66850344395742 2.38952085714692e-05 0.000342646460681284 GO:0101005 deubiquitinase activity 38/3194 115/18639 0.330434782608696 1.92829490076502 2.41044787014822e-05 0.000342646460681284 GO:0042809 nuclear vitamin D receptor binding 10/3194 15/18639 0.666666666666667 3.89041953663118 2.79337979104244e-05 0.000392856179123202 GO:0000993 RNA polymerase II complex binding 17/3194 36/18639 0.472222222222222 2.75571383844709 2.84760008058879e-05 0.000396266032267199 GO:0004843 cysteine-type deubiquitinase activity 36/3194 108/18639 0.333333333333333 1.94520976831559 3.15770291595253e-05 0.00043484200571763 GO:1901981 phosphatidylinositol phosphate binding 54/3194 185/18639 0.291891891891892 1.70337287820068 3.19962901679687e-05 0.000436073150536646 GO:0051721 protein phosphatase 2A binding 15/3194 30/18639 0.5 2.91781465247339 3.61525955015411e-05 0.000487691135235075 GO:0043539 protein serine/threonine kinase activator activity 27/3194 73/18639 0.36986301369863 2.15838344155566 3.89862825366752e-05 0.00052060470215641 GO:0001217 DNA-binding transcription repressor activity 74/3194 278/18639 0.266187050359712 1.55336895167648 4.31274992683179e-05 0.000570145540327162 GO:0070063 RNA polymerase binding 23/3194 59/18639 0.389830508474576 2.27490633921654 5.53267872014203e-05 0.000724178343369085 GO:0005085 guanyl-nucleotide exchange factor activity 63/3194 230/18639 0.273913043478261 1.5984549835289 6.28006760495636e-05 0.000800909427709697 GO:0031490 chromatin DNA binding 40/3194 128/18639 0.3125 1.82363415779587 6.28559920551766e-05 0.000800909427709697 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 10/3194 16/18639 0.625 3.64726831559173 6.30064905308688e-05 0.000800909427709697 GO:0051019 mitogen-activated protein kinase binding 14/3194 28/18639 0.5 2.91781465247339 6.59060736288526e-05 0.00082978885083184 GO:0008139 nuclear localization sequence binding 13/3194 25/18639 0.52 3.03452723857232 7.13785309380832e-05 0.000890211489624018 GO:0070034 telomerase RNA binding 12/3194 22/18639 0.545454545454545 3.18307052997097 7.39704394479964e-05 0.000913915149067769 GO:0061631 ubiquitin conjugating enzyme activity 16/3194 35/18639 0.457142857142857 2.66771625368995 7.99303378016607e-05 0.000978406542349958 GO:0043175 RNA polymerase core enzyme binding 18/3194 42/18639 0.428571428571429 2.50098398783433 8.27555719187912e-05 0.00100369601905176 GO:0003779 actin binding 107/3194 443/18639 0.241534988713318 1.40950865830543 9.07064250423496e-05 0.00109012630823624 GO:0051219 phosphoprotein binding 31/3194 93/18639 0.333333333333333 1.94520976831559 0.000108724940431496 0.00129490424549944 GO:0050681 nuclear androgen receptor binding 13/3194 26/18639 0.5 2.91781465247339 0.000120401523971264 0.00142116798830367 GO:0071889 14-3-3 protein binding 15/3194 33/18639 0.454545454545455 2.65255877497581 0.000144339547366696 0.00168864497007763 GO:0032451 demethylase activity 17/3194 40/18639 0.425 2.48014245460238 0.000147073197163574 0.00170553304079162 GO:0045309 protein phosphorylated amino acid binding 22/3194 59/18639 0.372881355932203 2.17599736794625 0.000172221147796248 0.00197979441205774 GO:0008234 cysteine-type peptidase activity 52/3194 187/18639 0.27807486631016 1.62274183880873 0.000174763412569293 0.0019917002708328 GO:0005096 GTPase activator activity 70/3194 271/18639 0.25830258302583 1.50735812304898 0.000183969230357022 0.00207869506437592 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 17/3194 41/18639 0.414634146341463 2.41965117522183 0.000211405269177183 0.00234855265422047 GO:0061650 ubiquitin-like protein conjugating enzyme activity 17/3194 41/18639 0.414634146341463 2.41965117522183 0.000211405269177183 0.00234855265422047 GO:0140104 molecular carrier activity 65/3194 249/18639 0.261044176706827 1.52335704747607 0.000222769873870931 0.00245418144381142 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 69/3194 268/18639 0.257462686567164 1.50245679866167 0.000225632247693311 0.00245422481648993 GO:0001098 basal transcription machinery binding 22/3194 60/18639 0.366666666666667 2.13973074514715 0.000228343156148458 0.00245422481648993 GO:0001099 basal RNA polymerase II transcription machinery binding 22/3194 60/18639 0.366666666666667 2.13973074514715 0.000228343156148458 0.00245422481648993 GO:1990841 promoter-specific chromatin binding 24/3194 68/18639 0.352941176470588 2.05963387233416 0.000237640419548175 0.00250483558596812 GO:0004715 non-membrane spanning protein tyrosine kinase activity 18/3194 45/18639 0.4 2.33425172197871 0.000238736220750366 0.00250483558596812 GO:0046915 transition metal ion transmembrane transporter activity 18/3194 45/18639 0.4 2.33425172197871 0.000238736220750366 0.00250483558596812 GO:0017124 SH3 domain binding 35/3194 115/18639 0.304347826086957 1.77606109280989 0.000309588207243476 0.00322264259823524 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 7/3194 10/18639 0.7 4.08494051346274 0.00031886005757407 0.00324256150856093 GO:0099122 RNA polymerase II C-terminal domain binding 7/3194 10/18639 0.7 4.08494051346274 0.00031886005757407 0.00324256150856093 GO:1905394 retromer complex binding 7/3194 10/18639 0.7 4.08494051346274 0.00031886005757407 0.00324256150856093 GO:0140272 exogenous protein binding 27/3194 82/18639 0.329268292682927 1.92148769797028 0.000367919563355792 0.00371289818897982 GO:0140597 protein carrier chaperone 51/3194 188/18639 0.271276595744681 1.58306965187386 0.000383695078162793 0.00384276434341828 GO:0015631 tubulin binding 92/3194 385/18639 0.238961038961039 1.39448804170157 0.000399876785861961 0.00395711328028141 GO:0051087 protein-folding chaperone binding 39/3194 134/18639 0.291044776119403 1.69842942457406 0.000401099228107193 0.00395711328028141 GO:0043560 insulin receptor substrate binding 8/3194 13/18639 0.615384615384615 3.59115649535186 0.000418256262425171 0.00409581317723019 GO:0140658 ATP-dependent chromatin remodeler activity 44/3194 158/18639 0.278481012658228 1.62511195833961 0.000511195530920794 0.0049691212638036 GO:0004532 RNA exonuclease activity 16/3194 40/18639 0.4 2.33425172197871 0.000523571689102255 0.00501566502168972 GO:0030331 nuclear estrogen receptor binding 16/3194 40/18639 0.4 2.33425172197871 0.000523571689102255 0.00501566502168972 GO:0140311 protein sequestering activity 14/3194 33/18639 0.424242424242424 2.47572152331075 0.000572892324484035 0.00544865937386974 GO:0140693 molecular condensate scaffold activity 18/3194 48/18639 0.375 2.18836098935504 0.000605638137837504 0.00569211876149144 GO:0140034 methylation-dependent protein binding 25/3194 76/18639 0.328947368421053 1.91961490294302 0.000607101925393565 0.00569211876149144 GO:0140713 histone chaperone activity 45/3194 164/18639 0.274390243902439 1.60123974830857 0.000629076403120589 0.00585661271074238 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 21/3194 60/18639 0.35 2.04247025673137 0.000647588123387648 0.00598679370012917 GO:0001618 virus receptor activity 26/3194 81/18639 0.320987654320988 1.87316496208168 0.000725949593202952 0.00666462057093265 GO:0016004 phospholipase activator activity 10/3194 20/18639 0.5 2.91781465247339 0.000746430163952953 0.00676158073538694 GO:0180030 inositol phosphate kinase activity 7/3194 11/18639 0.636363636363636 3.71358228496613 0.00074674038378706 0.00676158073538694 GO:0002039 p53 binding 23/3194 69/18639 0.333333333333333 1.94520976831559 0.000802591137389726 0.00721786043285182 GO:0046965 nuclear retinoid X receptor binding 9/3194 17/18639 0.529411764705882 3.08945080850123 0.000814010119944631 0.00722229113132082 GO:1990226 histone methyltransferase binding 9/3194 17/18639 0.529411764705882 3.08945080850123 0.000814010119944631 0.00722229113132082 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 14/3194 34/18639 0.411764705882353 2.40290618438985 0.000821607717253486 0.00724110268139406 GO:0005545 1-phosphatidylinositol binding 8/3194 14/18639 0.571428571428571 3.33464531711244 0.000829307866207151 0.00726056290811824 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 15/3194 38/18639 0.394736842105263 2.30353788353162 0.000915213206019774 0.00795994643656671 GO:0035064 methylated histone binding 24/3194 74/18639 0.324324324324324 1.89263653133409 0.000970131708356501 0.00838244521860976 GO:0004402 histone acetyltransferase activity 16/3194 42/18639 0.380952380952381 2.22309687807496 0.000984571203725936 0.00839743955693992 GO:0048487 beta-tubulin binding 16/3194 42/18639 0.380952380952381 2.22309687807496 0.000984571203725936 0.00839743955693992 GO:0016411 acylglycerol O-acyltransferase activity 13/3194 31/18639 0.419354838709677 2.44719938594542 0.00102252588064256 0.00842074153505584 GO:0004713 protein tyrosine kinase activity 39/3194 140/18639 0.278571428571429 1.62563959209232 0.00102308174290695 0.00842074153505584 GO:0042625 ATPase-coupled ion transmembrane transporter activity 11/3194 24/18639 0.458333333333333 2.67466343143394 0.00102552147287745 0.00842074153505584 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 11/3194 24/18639 0.458333333333333 2.67466343143394 0.00102552147287745 0.00842074153505584 GO:0046961 proton-transporting ATPase activity, rotational mechanism 11/3194 24/18639 0.458333333333333 2.67466343143394 0.00102552147287745 0.00842074153505584 GO:0060229 lipase activator activity 11/3194 24/18639 0.458333333333333 2.67466343143394 0.00102552147287745 0.00842074153505584 GO:0140463 chromatin-protein adaptor activity 19/3194 54/18639 0.351851851851852 2.05327697766646 0.0010709481738078 0.00873946596156738 GO:0004896 cytokine receptor activity 29/3194 96/18639 0.302083333333333 1.762846352536 0.00111042880227876 0.00900605445774551 GO:0000175 3'-5'-RNA exonuclease activity 14/3194 35/18639 0.4 2.33425172197871 0.00115546264037436 0.00931415616204213 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 10/3194 21/18639 0.476190476190476 2.7788710975937 0.00120729164442624 0.00961469610802099 GO:0051010 microtubule plus-end binding 10/3194 21/18639 0.476190476190476 2.7788710975937 0.00120729164442624 0.00961469610802099 GO:0001784 phosphotyrosine residue binding 17/3194 47/18639 0.361702127659574 2.11075953583181 0.00136154745492957 0.0107140817584339 GO:0061733 protein-lysine-acetyltransferase activity 17/3194 47/18639 0.361702127659574 2.11075953583181 0.00136154745492957 0.0107140817584339 GO:0051059 NF-kappaB binding 13/3194 32/18639 0.40625 2.37072440513463 0.00145456639264793 0.0113113927710622 GO:0120015 sterol transfer activity 13/3194 32/18639 0.40625 2.37072440513463 0.00145456639264793 0.0113113927710622 GO:0008017 microtubule binding 67/3194 276/18639 0.242753623188406 1.41662015736027 0.00149891018521648 0.0115415880514035 GO:0061578 K63-linked deubiquitinase activity 8/3194 15/18639 0.533333333333333 3.11233562930495 0.00151078176803695 0.0115415880514035 GO:0120283 protein serine/threonine kinase binding 8/3194 15/18639 0.533333333333333 3.11233562930495 0.00151078176803695 0.0115415880514035 GO:1990247 N6-methyladenosine-containing RNA reader activity 7/3194 12/18639 0.583333333333333 3.40411709455229 0.00152702706284657 0.0115415880514035 GO:0140674 ATP-dependent histone chaperone activity 41/3194 152/18639 0.269736842105263 1.57408422041327 0.0015278199009044 0.0115415880514035 GO:0120020 cholesterol transfer activity 11/3194 25/18639 0.44 2.56767689417658 0.00154988300062833 0.0116417348115378 GO:0019888 protein phosphatase regulator activity 31/3194 107/18639 0.289719626168224 1.69069634068551 0.00162567899851519 0.0121420770397575 GO:0071949 FAD binding 15/3194 40/18639 0.375 2.18836098935504 0.00169243902986328 0.0125696876262879 GO:0061775 cohesin loader activity 41/3194 153/18639 0.26797385620915 1.56379608825371 0.00174782208292716 0.0129084960537972 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 12/3194 29/18639 0.413793103448276 2.41474316066763 0.00182387601013649 0.0133953560300024 GO:0042578 phosphoric ester hydrolase activity 84/3194 363/18639 0.231404958677686 1.3503935581695 0.0019014026250418 0.0138875926536202 GO:0019208 phosphatase regulator activity 33/3194 117/18639 0.282051282051282 1.64594672703627 0.00191683414800369 0.0139233777124224 GO:0120013 lipid transfer activity 21/3194 65/18639 0.323076923076923 1.88535716005973 0.00206955254907277 0.0149505380867442 GO:0016779 nucleotidyltransferase activity 37/3194 136/18639 0.272058823529412 1.58763444325758 0.00214185498190493 0.0153887624243387 GO:1990380 K48-linked deubiquitinase activity 9/3194 19/18639 0.473684210526316 2.76424546023795 0.00222819749447497 0.0159225788524103 GO:0001727 lipid kinase activity 15/3194 41/18639 0.365853658536585 2.13498633107809 0.00225152412525307 0.0160027682450783 GO:0052742 phosphatidylinositol kinase activity 11/3194 26/18639 0.423076923076923 2.46892009055441 0.00227437556310134 0.0160787406118715 GO:0016763 pentosyltransferase activity 17/3194 49/18639 0.346938775510204 2.0246060853897 0.00229161649698643 0.0161144521756174 GO:0000510 H3-H4 histone complex chaperone activity 40/3194 151/18639 0.264900662251656 1.54586206753557 0.00247800053613395 0.0170620661915056 GO:0140584 chromatin extrusion motor activity 40/3194 151/18639 0.264900662251656 1.54586206753557 0.00247800053613395 0.0170620661915056 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 40/3194 151/18639 0.264900662251656 1.54586206753557 0.00247800053613395 0.0170620661915056 GO:0140849 ATP-dependent H2AZ histone chaperone activity 40/3194 151/18639 0.264900662251656 1.54586206753557 0.00247800053613395 0.0170620661915056 GO:0030275 LRR domain binding 8/3194 16/18639 0.5 2.91781465247339 0.00256995884765683 0.0174303504043859 GO:0140327 flippase activity 8/3194 16/18639 0.5 2.91781465247339 0.00256995884765683 0.0174303504043859 GO:0031624 ubiquitin conjugating enzyme binding 12/3194 30/18639 0.4 2.33425172197871 0.00257104260881638 0.0174303504043859 GO:0015291 secondary active transmembrane transporter activity 68/3194 287/18639 0.236933797909408 1.38265781441248 0.00265750619517189 0.0179246081123328 GO:0004197 cysteine-type endopeptidase activity 26/3194 88/18639 0.295454545454545 1.72416320373427 0.00275575468642437 0.0181010870951445 GO:0035401 histone H3Y41 kinase activity 32/3194 115/18639 0.278260869565217 1.62382728485475 0.00280984347836092 0.0181010870951445 GO:0140801 histone H2AXY142 kinase activity 32/3194 115/18639 0.278260869565217 1.62382728485475 0.00280984347836092 0.0181010870951445 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 10/3194 23/18639 0.434782608695652 2.53723013258555 0.00281381002170433 0.0181010870951445 GO:0042171 lysophosphatidic acid acyltransferase activity 10/3194 23/18639 0.434782608695652 2.53723013258555 0.00281381002170433 0.0181010870951445 GO:0071617 lysophospholipid acyltransferase activity 10/3194 23/18639 0.434782608695652 2.53723013258555 0.00281381002170433 0.0181010870951445 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 10/3194 23/18639 0.434782608695652 2.53723013258555 0.00281381002170433 0.0181010870951445 GO:0015616 DNA translocase activity 40/3194 152/18639 0.263157894736842 1.53569192235441 0.00281735076300164 0.0181010870951445 GO:0042975 peroxisome proliferator activated receptor binding 6/3194 10/18639 0.6 3.50137758296807 0.00281916827495857 0.0181010870951445 GO:0004535 poly(A)-specific ribonuclease activity 7/3194 13/18639 0.538461538461538 3.14226193343288 0.00282059299667154 0.0181010870951445 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 18/3194 54/18639 0.333333333333333 1.94520976831559 0.00286080681886441 0.0182689679993888 GO:0016791 phosphatase activity 65/3194 273/18639 0.238095238095238 1.38943554879685 0.00287439133424574 0.0182689679993888 GO:0032813 tumor necrosis factor receptor superfamily binding 17/3194 50/18639 0.34 1.9841139636819 0.00292629051175686 0.0185098375911128 GO:0008094 ATP-dependent activity, acting on DNA 52/3194 210/18639 0.247619047619048 1.44501297074873 0.00307084373291581 0.0193316924519748 GO:0140767 enzyme-substrate adaptor activity 37/3194 139/18639 0.266187050359712 1.55336895167648 0.00321627583443879 0.0201512637589008 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 11/3194 27/18639 0.407407407407407 2.37747860571906 0.00325034641080498 0.0202686695994537 GO:0003727 single-stranded RNA binding 26/3194 89/18639 0.292134831460674 1.7047905834676 0.00327008763429538 0.0202960368663779 GO:0042288 MHC class I protein binding 9/3194 20/18639 0.45 2.62603318722605 0.00344055258308389 0.0211553977434275 GO:0061608 nuclear import signal receptor activity 9/3194 20/18639 0.45 2.62603318722605 0.00344055258308389 0.0211553977434275 GO:0072349 modified amino acid transmembrane transporter activity 12/3194 31/18639 0.387096774193548 2.25895327933424 0.00354905317397878 0.0217215198888886 GO:0005048 signal sequence binding 17/3194 51/18639 0.333333333333333 1.94520976831559 0.00370011911339999 0.0224188007354775 GO:0030544 Hsp70 protein binding 17/3194 51/18639 0.333333333333333 1.94520976831559 0.00370011911339999 0.0224188007354775 GO:0010485 histone H4 acetyltransferase activity 13/3194 35/18639 0.371428571428571 2.16751945612309 0.00373081404069974 0.0224188007354775 GO:0140566 histone reader activity 13/3194 35/18639 0.371428571428571 2.16751945612309 0.00373081404069974 0.0224188007354775 GO:1990782 protein tyrosine kinase binding 32/3194 117/18639 0.273504273504274 1.59606955348972 0.00375873997954518 0.0224844083844286 GO:0140789 histone phosphatase activity 36/3194 136/18639 0.264705882352941 1.54472540425062 0.00400030048836761 0.0238216092145134 GO:0035035 histone acetyltransferase binding 10/3194 24/18639 0.416666666666667 2.43151221039449 0.00409115898515209 0.024253417840229 GO:0051787 misfolded protein binding 8/3194 17/18639 0.470588235294118 2.74617849644554 0.00413080216117879 0.0243791091833856 GO:0042826 histone deacetylase binding 34/3194 127/18639 0.267716535433071 1.56229445959205 0.00417437790206665 0.024526789273476 GO:0019789 SUMO transferase activity 11/3194 28/18639 0.392857142857143 2.2925686555148 0.00453532657429511 0.0265296536779563 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 55/3194 229/18639 0.240174672489083 1.40157035708329 0.00475402429745109 0.0276448418502666 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 34/3194 128/18639 0.265625 1.55008903412649 0.00476779420715642 0.0276448418502666 GO:0070717 poly-purine tract binding 12/3194 32/18639 0.375 2.18836098935504 0.0048057452427773 0.0276578386264073 GO:0032454 histone H3K9 demethylase activity 7/3194 14/18639 0.5 2.91781465247339 0.00481187812713591 0.0276578386264073 GO:0044390 ubiquitin-like protein conjugating enzyme binding 13/3194 36/18639 0.361111111111111 2.10731058234189 0.00493755635047378 0.0282573571226249 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 14/3194 40/18639 0.35 2.04247025673137 0.00496238358620127 0.0282770306075779 GO:0009931 calcium-dependent protein serine/threonine kinase activity 9/3194 21/18639 0.428571428571429 2.50098398783433 0.00511549828707714 0.0289003792116068 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 9/3194 21/18639 0.428571428571429 2.50098398783433 0.00511549828707714 0.0289003792116068 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 24/3194 83/18639 0.289156626506024 1.6874108833581 0.00530276792212905 0.0293499584353545 GO:0003953 NAD+ nucleosidase activity 6/3194 11/18639 0.545454545454545 3.18307052997097 0.00530608174436438 0.0293499584353545 GO:0005536 D-glucose binding 6/3194 11/18639 0.545454545454545 3.18307052997097 0.00530608174436438 0.0293499584353545 GO:0015173 aromatic amino acid transmembrane transporter activity 6/3194 11/18639 0.545454545454545 3.18307052997097 0.00530608174436438 0.0293499584353545 GO:0043522 leucine zipper domain binding 6/3194 11/18639 0.545454545454545 3.18307052997097 0.00530608174436438 0.0293499584353545 GO:0016504 peptidase activator activity 18/3194 57/18639 0.315789473684211 1.8428303068253 0.00548045276236874 0.0301881606327145 GO:0034212 protein N-acetyltransferase activity 17/3194 53/18639 0.320754716981132 1.871805626115 0.00575451491472812 0.0315662602376372 GO:0004709 MAP kinase kinase kinase activity 10/3194 25/18639 0.4 2.33425172197871 0.00578534297483462 0.0316042289782288 GO:0060590 ATPase regulator activity 16/3194 49/18639 0.326530612244898 1.90551160977854 0.00600419986217909 0.0326648239415669 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 11/3194 29/18639 0.379310344827586 2.21351456394533 0.00619232414128091 0.0333675039256469 GO:0097472 cyclin-dependent protein kinase activity 11/3194 29/18639 0.379310344827586 2.21351456394533 0.00619232414128091 0.0333675039256469 GO:0051213 dioxygenase activity 26/3194 93/18639 0.279569892473118 1.63146625729695 0.00620908166846379 0.0333675039256469 GO:0005319 lipid transporter activity 44/3194 178/18639 0.247191011235955 1.44251510908797 0.00628823501936039 0.0336560594963337 GO:0140828 metal cation:monoatomic cation antiporter activity 14/3194 41/18639 0.341463414634146 1.99265390900622 0.00636801441780402 0.0339431498158648 GO:0019239 deaminase activity 12/3194 33/18639 0.363636363636364 2.12204701998065 0.00639322564610464 0.0339431498158648 GO:0003689 DNA clamp loader activity 40/3194 160/18639 0.25 1.45890732623669 0.00727334544788718 0.0384614507284274 GO:0140517 protein-RNA adaptor activity 9/3194 22/18639 0.409090909090909 2.38730289747823 0.00735831614756071 0.0387557527771923 GO:0004721 phosphoprotein phosphatase activity 43/3194 175/18639 0.245714285714286 1.43389748635835 0.00764578471187292 0.0401100293218095 GO:0015101 organic cation transmembrane transporter activity 23/3194 81/18639 0.283950617283951 1.65703054337995 0.00793404119671778 0.0401869826132601 GO:0033192 calmodulin-dependent protein phosphatase activity 23/3194 81/18639 0.283950617283951 1.65703054337995 0.00793404119671778 0.0401869826132601 GO:0140791 histone H2AXS140 phosphatase activity 23/3194 81/18639 0.283950617283951 1.65703054337995 0.00793404119671778 0.0401869826132601 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 23/3194 81/18639 0.283950617283951 1.65703054337995 0.00793404119671778 0.0401869826132601 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 23/3194 81/18639 0.283950617283951 1.65703054337995 0.00793404119671778 0.0401869826132601 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 23/3194 81/18639 0.283950617283951 1.65703054337995 0.00793404119671778 0.0401869826132601 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 23/3194 81/18639 0.283950617283951 1.65703054337995 0.00793404119671778 0.0401869826132601 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 23/3194 81/18639 0.283950617283951 1.65703054337995 0.00793404119671778 0.0401869826132601 GO:1990439 MAP kinase serine/threonine phosphatase activity 23/3194 81/18639 0.283950617283951 1.65703054337995 0.00793404119671778 0.0401869826132601 GO:0070412 R-SMAD binding 10/3194 26/18639 0.384615384615385 2.24447280959491 0.0079796976071679 0.0402639703689922 GO:0140097 catalytic activity, acting on DNA 75/3194 336/18639 0.223214285714286 1.30259582699705 0.00811982088101307 0.0408152213106436 GO:0043531 ADP binding 13/3194 38/18639 0.342105263157895 1.99639949906074 0.00827925457101986 0.0414589944806373 GO:0008374 O-acyltransferase activity 17/3194 55/18639 0.309090909090909 1.80373996698355 0.00865043162091991 0.0431542286900231 GO:0004000 adenosine deaminase activity 6/3194 12/18639 0.5 2.91781465247339 0.00908513642588219 0.0448154863993144 GO:0035197 siRNA binding 6/3194 12/18639 0.5 2.91781465247339 0.00908513642588219 0.0448154863993144 GO:0097677 STAT family protein binding 6/3194 12/18639 0.5 2.91781465247339 0.00908513642588219 0.0448154863993144 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 23/3194 82/18639 0.280487804878049 1.63682285382653 0.00927927505274603 0.045434080073075 GO:0033549 MAP kinase phosphatase activity 23/3194 82/18639 0.280487804878049 1.63682285382653 0.00927927505274603 0.045434080073075 GO:0140938 histone H3 methyltransferase activity 15/3194 47/18639 0.319148936170213 1.86243488455748 0.00966592232963519 0.047152580515785 GO:0098531 ligand-modulated transcription factor activity 18/3194 60/18639 0.3 1.75068879148403 0.00979243306006511 0.047594104799287 GO:0005158 insulin receptor binding 9/3194 23/18639 0.391304347826087 2.283507119327 0.0102797843713255 0.0494177270505176 GO:0044013 histone H2B acetyltransferase activity 9/3194 23/18639 0.391304347826087 2.283507119327 0.0102797843713255 0.0494177270505176 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 9/3194 23/18639 0.391304347826087 2.283507119327 0.0102797843713255 0.0494177270505176 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 13/3194 39/18639 0.333333333333333 1.94520976831559 0.0105099303607883 0.0503410432498628 GO:0001671 ATPase activator activity 10/3194 27/18639 0.37037037037037 2.16134418701732 0.0107616688991461 0.0511912648146569 GO:0005154 epidermal growth factor receptor binding 12/3194 35/18639 0.342857142857143 2.00078719026747 0.0107861986827602 0.0511912648146569 GO:0008135 translation factor activity, RNA binding 23/3194 83/18639 0.27710843373494 1.61710209655152 0.0108036027861492 0.0511912648146569 GO:0005164 tumor necrosis factor receptor binding 11/3194 31/18639 0.354838709677419 2.07070717272305 0.0108957468642718 0.0514434905520263 GO:0048029 monosaccharide binding 21/3194 74/18639 0.283783783783784 1.65605696491733 0.010945739231272 0.0514956130382263 GO:0015297 antiporter activity 34/3194 135/18639 0.251851851851852 1.46971404717178 0.0112389721139886 0.0526876635982019 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 7/3194 16/18639 0.4375 2.55308782091421 0.0116906319031069 0.053969286990155 GO:0070411 I-SMAD binding 7/3194 16/18639 0.4375 2.55308782091421 0.0116906319031069 0.053969286990155 GO:0140328 floppase activity 7/3194 16/18639 0.4375 2.55308782091421 0.0116906319031069 0.053969286990155 GO:0051015 actin filament binding 49/3194 209/18639 0.23444976076555 1.36816189446121 0.0117117820464463 0.053969286990155 GO:0003697 single-stranded DNA binding 31/3194 121/18639 0.256198347107438 1.49507858225909 0.011716479096955 0.053969286990155 GO:0097110 scaffold protein binding 20/3194 70/18639 0.285714285714286 1.66732265855622 0.0118744960155113 0.0545072351823124 GO:0004386 helicase activity 38/3194 155/18639 0.245161290322581 1.43067041024502 0.0120442166396752 0.0550949979157462 GO:0017018 myosin phosphatase activity 23/3194 84/18639 0.273809523809524 1.59785088111638 0.0125232515240483 0.0568515822629215 GO:0180051 translation factor activity 23/3194 84/18639 0.273809523809524 1.59785088111638 0.0125232515240483 0.0568515822629215 GO:0001223 transcription coactivator binding 14/3194 44/18639 0.318181818181818 1.85679114248306 0.0125572329960462 0.0568515822629215 GO:0022804 active transmembrane transporter activity 97/3194 457/18639 0.212253829321663 1.23863466647667 0.012660157340903 0.0569282538940016 GO:0004725 protein tyrosine phosphatase activity 26/3194 98/18639 0.26530612244898 1.54822818294506 0.0126602924696191 0.0569282538940016 GO:0004722 protein serine/threonine phosphatase activity 27/3194 103/18639 0.262135922330097 1.52972807022877 0.0131802167068322 0.0588474479249733 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 24/3194 89/18639 0.269662921348315 1.57365284627778 0.0132206445035681 0.0588474479249733 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 24/3194 89/18639 0.269662921348315 1.57365284627778 0.0132206445035681 0.0588474479249733 GO:0140296 general transcription initiation factor binding 16/3194 53/18639 0.30188679245283 1.76169941281412 0.0135301157293259 0.0598221170373539 GO:1901505 carbohydrate derivative transmembrane transporter activity 16/3194 53/18639 0.30188679245283 1.76169941281412 0.0135301157293259 0.0598221170373539 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 9/3194 24/18639 0.375 2.18836098935504 0.0139929596030296 0.0612539489907455 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 9/3194 24/18639 0.375 2.18836098935504 0.0139929596030296 0.0612539489907455 GO:0043998 histone H2A acetyltransferase activity 9/3194 24/18639 0.375 2.18836098935504 0.0139929596030296 0.0612539489907455 GO:0046875 ephrin receptor binding 10/3194 28/18639 0.357142857142857 2.08415332319528 0.0142207479685077 0.0614442861578378 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 10/3194 28/18639 0.357142857142857 2.08415332319528 0.0142207479685077 0.0614442861578378 GO:0030955 potassium ion binding 6/3194 13/18639 0.461538461538462 2.6933673715139 0.0144547450794913 0.0614442861578378 GO:0032396 inhibitory MHC class I receptor activity 6/3194 13/18639 0.461538461538462 2.6933673715139 0.0144547450794913 0.0614442861578378 GO:0035325 Toll-like receptor binding 6/3194 13/18639 0.461538461538462 2.6933673715139 0.0144547450794913 0.0614442861578378 GO:0046974 histone H3K9 methyltransferase activity 6/3194 13/18639 0.461538461538462 2.6933673715139 0.0144547450794913 0.0614442861578378 GO:0140333 glycerophospholipid flippase activity 6/3194 13/18639 0.461538461538462 2.6933673715139 0.0144547450794913 0.0614442861578378 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 6/3194 13/18639 0.461538461538462 2.6933673715139 0.0144547450794913 0.0614442861578378 GO:0140852 histone ubiquitin ligase activity 6/3194 13/18639 0.461538461538462 2.6933673715139 0.0144547450794913 0.0614442861578378 GO:0140793 histone H2AXY142 phosphatase activity 24/3194 90/18639 0.266666666666667 1.55616781465247 0.0151739790724795 0.064294872864801 GO:0140303 intramembrane lipid transporter activity 14/3194 45/18639 0.311111111111111 1.81552911709455 0.0154214430557887 0.0651346572516061 GO:0042169 SH2 domain binding 13/3194 41/18639 0.317073170731707 1.85032148693434 0.0163441299994686 0.0685934598707859 GO:0042287 MHC protein binding 13/3194 41/18639 0.317073170731707 1.85032148693434 0.0163441299994686 0.0685934598707859 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 7/3194 17/18639 0.411764705882353 2.40290618438985 0.0169825127224566 0.0708229710381315 GO:0008429 phosphatidylethanolamine binding 7/3194 17/18639 0.411764705882353 2.40290618438985 0.0169825127224566 0.0708229710381315 GO:0004382 GDP phosphatase activity 5/3194 10/18639 0.5 2.91781465247339 0.0173468293039836 0.0712189699995849 GO:0004445 inositol-polyphosphate 5-phosphatase activity 5/3194 10/18639 0.5 2.91781465247339 0.0173468293039836 0.0712189699995849 GO:0005381 iron ion transmembrane transporter activity 5/3194 10/18639 0.5 2.91781465247339 0.0173468293039836 0.0712189699995849 GO:0008140 cAMP response element binding protein binding 5/3194 10/18639 0.5 2.91781465247339 0.0173468293039836 0.0712189699995849 GO:0051864 histone H3K36 demethylase activity 5/3194 10/18639 0.5 2.91781465247339 0.0173468293039836 0.0712189699995849 GO:0019955 cytokine binding 35/3194 144/18639 0.243055555555556 1.41838212273012 0.0175940187046244 0.0719191258918617 GO:0005548 phospholipid transporter activity 19/3194 68/18639 0.279411764705882 1.63054348226454 0.0177349735557843 0.0719191258918617 GO:0030145 manganese ion binding 19/3194 68/18639 0.279411764705882 1.63054348226454 0.0177349735557843 0.0719191258918617 GO:0032934 sterol binding 19/3194 68/18639 0.279411764705882 1.63054348226454 0.0177349735557843 0.0719191258918617 GO:0004879 nuclear receptor activity 17/3194 59/18639 0.288135593220339 1.68145251159483 0.0178618271600718 0.0722120351853668 GO:0016407 acetyltransferase activity 25/3194 96/18639 0.260416666666667 1.51969513149656 0.0180098038434398 0.0725882947592299 GO:0019200 carbohydrate kinase activity 8/3194 21/18639 0.380952380952381 2.22309687807496 0.0182218331667016 0.0732196457336761 GO:0010484 histone H3 acetyltransferase activity 10/3194 29/18639 0.344827586206897 2.01228596722303 0.0184462341933639 0.0736734791650363 GO:0051861 glycolipid binding 10/3194 29/18639 0.344827586206897 2.01228596722303 0.0184462341933639 0.0736734791650363 GO:0017056 structural constituent of nuclear pore 9/3194 25/18639 0.36 2.10082654978084 0.0186097439563894 0.0741026551516468 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 32/3194 130/18639 0.246153846153846 1.43646259814074 0.0188373240491713 0.0747836107898034 GO:1902936 phosphatidylinositol bisphosphate binding 28/3194 111/18639 0.252252252252252 1.47205063548207 0.0195953061658458 0.077559864524695 GO:0008080 N-acetyltransferase activity 19/3194 69/18639 0.27536231884058 1.60691241730418 0.0206496612120335 0.0814891108128604 GO:0001540 amyloid-beta binding 22/3194 83/18639 0.265060240963855 1.54679330974493 0.0208634394760788 0.082087699367191 GO:0005161 platelet-derived growth factor receptor binding 6/3194 14/18639 0.428571428571429 2.50098398783433 0.0216868952937579 0.08457249433141 GO:0046030 inositol trisphosphate phosphatase activity 6/3194 14/18639 0.428571428571429 2.50098398783433 0.0216868952937579 0.08457249433141 GO:0061665 SUMO ligase activity 6/3194 14/18639 0.428571428571429 2.50098398783433 0.0216868952937579 0.08457249433141 GO:0042626 ATPase-coupled transmembrane transporter activity 25/3194 98/18639 0.255102040816327 1.48868094513948 0.0230813188506797 0.0865841141791931 GO:0005516 calmodulin binding 47/3194 207/18639 0.227053140096618 1.32499795812801 0.0232354544579637 0.0865841141791931 GO:0001968 fibronectin binding 10/3194 30/18639 0.333333333333333 1.94520976831559 0.0235249235126395 0.0865841141791931 GO:0008187 poly-pyrimidine tract binding 10/3194 30/18639 0.333333333333333 1.94520976831559 0.0235249235126395 0.0865841141791931 GO:0015215 nucleotide transmembrane transporter activity 10/3194 30/18639 0.333333333333333 1.94520976831559 0.0235249235126395 0.0865841141791931 GO:0043995 histone H4K5 acetyltransferase activity 10/3194 30/18639 0.333333333333333 1.94520976831559 0.0235249235126395 0.0865841141791931 GO:0043996 histone H4K8 acetyltransferase activity 10/3194 30/18639 0.333333333333333 1.94520976831559 0.0235249235126395 0.0865841141791931 GO:0043997 histone H4K12 acetyltransferase activity 10/3194 30/18639 0.333333333333333 1.94520976831559 0.0235249235126395 0.0865841141791931 GO:0004706 JUN kinase kinase kinase activity 7/3194 18/18639 0.388888888888889 2.26941139636819 0.0237612156622506 0.0865841141791931 GO:0030228 lipoprotein particle receptor activity 7/3194 18/18639 0.388888888888889 2.26941139636819 0.0237612156622506 0.0865841141791931 GO:0032393 MHC class I receptor activity 7/3194 18/18639 0.388888888888889 2.26941139636819 0.0237612156622506 0.0865841141791931 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 7/3194 18/18639 0.388888888888889 2.26941139636819 0.0237612156622506 0.0865841141791931 GO:0070628 proteasome binding 7/3194 18/18639 0.388888888888889 2.26941139636819 0.0237612156622506 0.0865841141791931 GO:0043021 ribonucleoprotein complex binding 41/3194 177/18639 0.231638418079096 1.35175594069389 0.0238355074788917 0.0865841141791931 GO:0004112 cyclic-nucleotide phosphodiesterase activity 9/3194 26/18639 0.346153846153846 2.02002552863542 0.024237415553036 0.0865841141791931 GO:0051139 metal cation:proton antiporter activity 9/3194 26/18639 0.346153846153846 2.02002552863542 0.024237415553036 0.0865841141791931 GO:0004712 protein serine/threonine/tyrosine kinase activity 13/3194 43/18639 0.302325581395349 1.76426002242577 0.0243535489622109 0.0865841141791931 GO:0032931 histone H3K56 acetyltransferase activity 8/3194 22/18639 0.363636363636364 2.12204701998065 0.0244295571776392 0.0865841141791931 GO:0033691 sialic acid binding 8/3194 22/18639 0.363636363636364 2.12204701998065 0.0244295571776392 0.0865841141791931 GO:0043992 histone H3K9 acetyltransferase activity 8/3194 22/18639 0.363636363636364 2.12204701998065 0.0244295571776392 0.0865841141791931 GO:0043993 histone H3K18 acetyltransferase activity 8/3194 22/18639 0.363636363636364 2.12204701998065 0.0244295571776392 0.0865841141791931 GO:0043994 histone H3K23 acetyltransferase activity 8/3194 22/18639 0.363636363636364 2.12204701998065 0.0244295571776392 0.0865841141791931 GO:0043999 histone H2AK5 acetyltransferase activity 8/3194 22/18639 0.363636363636364 2.12204701998065 0.0244295571776392 0.0865841141791931 GO:0044012 histone H2AK9 acetyltransferase activity 8/3194 22/18639 0.363636363636364 2.12204701998065 0.0244295571776392 0.0865841141791931 GO:0044014 histone H2BK5 acetyltransferase activity 8/3194 22/18639 0.363636363636364 2.12204701998065 0.0244295571776392 0.0865841141791931 GO:0044015 histone H2BK12 acetyltransferase activity 8/3194 22/18639 0.363636363636364 2.12204701998065 0.0244295571776392 0.0865841141791931 GO:0044016 histone H3K4 acetyltransferase activity 8/3194 22/18639 0.363636363636364 2.12204701998065 0.0244295571776392 0.0865841141791931 GO:0044017 histone H3K27 acetyltransferase activity 8/3194 22/18639 0.363636363636364 2.12204701998065 0.0244295571776392 0.0865841141791931 GO:0044018 histone H3K36 acetyltransferase activity 8/3194 22/18639 0.363636363636364 2.12204701998065 0.0244295571776392 0.0865841141791931 GO:0046972 histone H4K16 acetyltransferase activity 8/3194 22/18639 0.363636363636364 2.12204701998065 0.0244295571776392 0.0865841141791931 GO:0050321 tau-protein kinase activity 8/3194 22/18639 0.363636363636364 2.12204701998065 0.0244295571776392 0.0865841141791931 GO:0061133 endopeptidase activator activity 8/3194 22/18639 0.363636363636364 2.12204701998065 0.0244295571776392 0.0865841141791931 GO:0140035 ubiquitin-like protein reader activity 8/3194 22/18639 0.363636363636364 2.12204701998065 0.0244295571776392 0.0865841141791931 GO:0140908 histone H3K122 acetyltransferase activity 8/3194 22/18639 0.363636363636364 2.12204701998065 0.0244295571776392 0.0865841141791931 GO:0030159 signaling receptor complex adaptor activity 15/3194 52/18639 0.288461538461538 1.68335460719619 0.0249072743090451 0.0880412209533627 GO:0016887 ATP hydrolysis activity 87/3194 417/18639 0.20863309352518 1.21750539455724 0.026124693038835 0.0920982511929062 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 14/3194 48/18639 0.291666666666667 1.70205854727614 0.0270398860823967 0.0945101790288432 GO:0000099 sulfur amino acid transmembrane transporter activity 5/3194 11/18639 0.454545454545455 2.65255877497581 0.0273807856036664 0.0945101790288432 GO:0005225 volume-sensitive anion channel activity 5/3194 11/18639 0.454545454545455 2.65255877497581 0.0273807856036664 0.0945101790288432 GO:0008432 JUN kinase binding 5/3194 11/18639 0.454545454545455 2.65255877497581 0.0273807856036664 0.0945101790288432 GO:0019107 myristoyltransferase activity 5/3194 11/18639 0.454545454545455 2.65255877497581 0.0273807856036664 0.0945101790288432 GO:0042608 T cell receptor binding 5/3194 11/18639 0.454545454545455 2.65255877497581 0.0273807856036664 0.0945101790288432 GO:0140031 phosphorylation-dependent protein binding 5/3194 11/18639 0.454545454545455 2.65255877497581 0.0273807856036664 0.0945101790288432 GO:0140537 transcription regulator activator activity 5/3194 11/18639 0.454545454545455 2.65255877497581 0.0273807856036664 0.0945101790288432 GO:0019210 kinase inhibitor activity 23/3194 90/18639 0.255555555555556 1.49132748904195 0.0278995184059729 0.0960499045122297 GO:0070851 growth factor receptor binding 33/3194 139/18639 0.237410071942446 1.38543717311686 0.0285136587569235 0.0979092386406568 GO:0001046 core promoter sequence-specific DNA binding 13/3194 44/18639 0.295454545454545 1.72416320373427 0.0293003911415702 0.100350044272425 GO:0004683 calcium/calmodulin-dependent protein kinase activity 9/3194 27/18639 0.333333333333333 1.94520976831559 0.030975288879981 0.104317799573212 GO:0005385 zinc ion transmembrane transporter activity 9/3194 27/18639 0.333333333333333 1.94520976831559 0.030975288879981 0.104317799573212 GO:0008266 poly(U) RNA binding 9/3194 27/18639 0.333333333333333 1.94520976831559 0.030975288879981 0.104317799573212 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 9/3194 27/18639 0.333333333333333 1.94520976831559 0.030975288879981 0.104317799573212 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 6/3194 15/18639 0.4 2.33425172197871 0.0310112671953648 0.104317799573212 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 6/3194 15/18639 0.4 2.33425172197871 0.0310112671953648 0.104317799573212 GO:0005041 low-density lipoprotein particle receptor activity 6/3194 15/18639 0.4 2.33425172197871 0.0310112671953648 0.104317799573212 GO:0043274 phospholipase binding 8/3194 23/18639 0.347826086956522 2.02978410606844 0.0319761026743397 0.107188555546905 GO:0005520 insulin-like growth factor binding 7/3194 19/18639 0.368421052631579 2.14996869129618 0.0321889989047815 0.107188555546905 GO:0046624 sphingolipid transporter activity 7/3194 19/18639 0.368421052631579 2.14996869129618 0.0321889989047815 0.107188555546905 GO:0140036 ubiquitin-modified protein reader activity 7/3194 19/18639 0.368421052631579 2.14996869129618 0.0321889989047815 0.107188555546905 GO:0003724 RNA helicase activity 20/3194 77/18639 0.25974025974026 1.51574787141475 0.0327877425392306 0.108908029238349 GO:0004857 enzyme inhibitor activity 86/3194 416/18639 0.206730769230769 1.20640413515727 0.0329353178192358 0.109124035481277 GO:0004540 RNA nuclease activity 29/3194 121/18639 0.239669421487603 1.3986218995327 0.0340479747437527 0.112528556528103 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 15/3194 54/18639 0.277777777777778 1.62100814026299 0.0344574933497492 0.113598020469747 GO:0005126 cytokine receptor binding 59/3194 275/18639 0.214545454545455 1.25200774178858 0.0360719131597038 0.118624550241613 GO:0001786 phosphatidylserine binding 16/3194 59/18639 0.271186440677966 1.58254354032455 0.0365133033000173 0.119348657254669 GO:0022884 macromolecule transmembrane transporter activity 10/3194 32/18639 0.3125 1.82363415779587 0.0365629396279434 0.119348657254669 GO:0140142 nucleocytoplasmic carrier activity 10/3194 32/18639 0.3125 1.82363415779587 0.0365629396279434 0.119348657254669 GO:0140318 protein transporter activity 12/3194 41/18639 0.292682926829268 1.70798906486247 0.0380115161694421 0.123771488610843 GO:0036408 histone H3K14 acetyltransferase activity 9/3194 28/18639 0.321428571428571 1.87573799087575 0.038911650364363 0.126391159168766 GO:0004875 complement receptor activity 5/3194 12/18639 0.416666666666667 2.43151221039449 0.0404491064449407 0.128234337458541 GO:0005095 GTPase inhibitor activity 5/3194 12/18639 0.416666666666667 2.43151221039449 0.0404491064449407 0.128234337458541 GO:0035497 cAMP response element binding 5/3194 12/18639 0.416666666666667 2.43151221039449 0.0404491064449407 0.128234337458541 GO:0042301 phosphate ion binding 5/3194 12/18639 0.416666666666667 2.43151221039449 0.0404491064449407 0.128234337458541 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 5/3194 12/18639 0.416666666666667 2.43151221039449 0.0404491064449407 0.128234337458541 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 5/3194 12/18639 0.416666666666667 2.43151221039449 0.0404491064449407 0.128234337458541 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 5/3194 12/18639 0.416666666666667 2.43151221039449 0.0404491064449407 0.128234337458541 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 5/3194 12/18639 0.416666666666667 2.43151221039449 0.0404491064449407 0.128234337458541 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 5/3194 12/18639 0.416666666666667 2.43151221039449 0.0404491064449407 0.128234337458541 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 5/3194 12/18639 0.416666666666667 2.43151221039449 0.0404491064449407 0.128234337458541 GO:0015295 solute:proton symporter activity 8/3194 24/18639 0.333333333333333 1.94520976831559 0.0409676742099948 0.129567620348357 GO:0008186 ATP-dependent activity, acting on RNA 20/3194 79/18639 0.253164556962025 1.47737450758146 0.0420797439231894 0.130677547902764 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 16/3194 60/18639 0.266666666666667 1.55616781465247 0.0421355762329353 0.130677547902764 GO:0015095 magnesium ion transmembrane transporter activity 7/3194 20/18639 0.35 2.04247025673137 0.0423982594057219 0.130677547902764 GO:0030742 GTP-dependent protein binding 7/3194 20/18639 0.35 2.04247025673137 0.0423982594057219 0.130677547902764 GO:0052745 inositol phosphate phosphatase activity 7/3194 20/18639 0.35 2.04247025673137 0.0423982594057219 0.130677547902764 GO:0004708 MAP kinase kinase activity 6/3194 16/18639 0.375 2.18836098935504 0.0426036483707196 0.130677547902764 GO:0005159 insulin-like growth factor receptor binding 6/3194 16/18639 0.375 2.18836098935504 0.0426036483707196 0.130677547902764 GO:0005521 lamin binding 6/3194 16/18639 0.375 2.18836098935504 0.0426036483707196 0.130677547902764 GO:0015385 sodium:proton antiporter activity 6/3194 16/18639 0.375 2.18836098935504 0.0426036483707196 0.130677547902764 GO:0022858 alanine transmembrane transporter activity 6/3194 16/18639 0.375 2.18836098935504 0.0426036483707196 0.130677547902764 GO:0031435 mitogen-activated protein kinase kinase kinase binding 6/3194 16/18639 0.375 2.18836098935504 0.0426036483707196 0.130677547902764 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 6/3194 16/18639 0.375 2.18836098935504 0.0426036483707196 0.130677547902764 GO:0055102 lipase inhibitor activity 6/3194 16/18639 0.375 2.18836098935504 0.0426036483707196 0.130677547902764 GO:0004860 protein kinase inhibitor activity 21/3194 84/18639 0.25 1.45890732623669 0.0429529298873678 0.131140354067206 GO:0051117 ATPase binding 21/3194 84/18639 0.25 1.45890732623669 0.0429529298873678 0.131140354067206 GO:0003743 translation initiation factor activity 14/3194 51/18639 0.274509803921569 1.6019374562599 0.0440897168454423 0.134300934722753 GO:0051879 Hsp90 protein binding 12/3194 42/18639 0.285714285714286 1.66732265855622 0.0451956096245731 0.137353094077438 GO:0016417 S-acyltransferase activity 9/3194 29/18639 0.310344827586207 1.81105737050072 0.0481210876413125 0.145908435462879 GO:0043495 protein-membrane adaptor activity 13/3194 47/18639 0.276595744680851 1.61411023328315 0.048459444439277 0.146598136267103 GO:0019706 protein-cysteine S-palmitoyltransferase activity 8/3194 25/18639 0.32 1.86740137758297 0.051489053152868 0.155053595143716 GO:0019707 protein-cysteine S-acyltransferase activity 8/3194 25/18639 0.32 1.86740137758297 0.051489053152868 0.155053595143716 GO:0030971 receptor tyrosine kinase binding 20/3194 81/18639 0.246913580246914 1.44089612467822 0.0531486716713031 0.159432383578702 GO:0015293 symporter activity 33/3194 146/18639 0.226027397260274 1.3190121031729 0.0531843276537123 0.159432383578702 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 21/3194 86/18639 0.244186046511628 1.42497924888235 0.0537976298428098 0.160834496305993 GO:0052866 phosphatidylinositol phosphate phosphatase activity 10/3194 34/18639 0.294117647058824 1.71636156027846 0.0538953720601778 0.160834496305993 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 7/3194 21/18639 0.333333333333333 1.94520976831559 0.0544864725252319 0.161867677928891 GO:0035613 RNA stem-loop binding 7/3194 21/18639 0.333333333333333 1.94520976831559 0.0544864725252319 0.161867677928891 GO:0015294 solute:monoatomic cation symporter activity 27/3194 116/18639 0.232758620689655 1.35829302787554 0.0548841292526511 0.162502617356719 GO:0000149 SNARE binding 25/3194 106/18639 0.235849056603774 1.37632766626103 0.0549460438414927 0.162502617356719 GO:0015179 L-amino acid transmembrane transporter activity 16/3194 62/18639 0.258064516129032 1.50596885288949 0.0551804533026473 0.162831605504687 GO:0032266 phosphatidylinositol-3-phosphate binding 13/3194 48/18639 0.270833333333333 1.58048293675642 0.0564152804004042 0.163649693883 GO:0038187 pattern recognition receptor activity 13/3194 48/18639 0.270833333333333 1.58048293675642 0.0564152804004042 0.163649693883 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 6/3194 17/18639 0.352941176470588 2.05963387233416 0.0565788132697721 0.163649693883 GO:0017110 nucleoside diphosphate phosphatase activity 6/3194 17/18639 0.352941176470588 2.05963387233416 0.0565788132697721 0.163649693883 GO:0030169 low-density lipoprotein particle binding 6/3194 17/18639 0.352941176470588 2.05963387233416 0.0565788132697721 0.163649693883 GO:0070403 NAD+ binding 6/3194 17/18639 0.352941176470588 2.05963387233416 0.0565788132697721 0.163649693883 GO:0042054 histone methyltransferase activity 17/3194 67/18639 0.253731343283582 1.48068206244918 0.05663914812046 0.163649693883 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 5/3194 13/18639 0.384615384615385 2.24447280959491 0.0566955822983466 0.163649693883 GO:0005035 death receptor activity 5/3194 13/18639 0.384615384615385 2.24447280959491 0.0566955822983466 0.163649693883 GO:0031994 insulin-like growth factor I binding 5/3194 13/18639 0.384615384615385 2.24447280959491 0.0566955822983466 0.163649693883 GO:0070566 adenylyltransferase activity 9/3194 30/18639 0.3 1.75068879148403 0.0586623008393153 0.168957650783388 GO:0008408 3'-5' exonuclease activity 15/3194 58/18639 0.258620689655172 1.50921447541727 0.0610190404634951 0.175363416288566 GO:0033218 amide binding 52/3194 247/18639 0.210526315789474 1.22855353788353 0.0622103096586782 0.178399196027706 GO:1901682 sulfur compound transmembrane transporter activity 16/3194 63/18639 0.253968253968254 1.48206458538331 0.0626497856263538 0.179270598697056 GO:0005112 Notch binding 8/3194 26/18639 0.307692307692308 1.79557824767593 0.0636008920861266 0.180043638839099 GO:0005160 transforming growth factor beta receptor binding 8/3194 26/18639 0.307692307692308 1.79557824767593 0.0636008920861266 0.180043638839099 GO:0008143 poly(A) binding 8/3194 26/18639 0.307692307692308 1.79557824767593 0.0636008920861266 0.180043638839099 GO:0008157 protein phosphatase 1 binding 8/3194 26/18639 0.307692307692308 1.79557824767593 0.0636008920861266 0.180043638839099 GO:0043548 phosphatidylinositol 3-kinase binding 8/3194 26/18639 0.307692307692308 1.79557824767593 0.0636008920861266 0.180043638839099 GO:0043015 gamma-tubulin binding 10/3194 35/18639 0.285714285714286 1.66732265855622 0.0643022118824074 0.181640008778937 GO:0015485 cholesterol binding 14/3194 54/18639 0.259259259259259 1.51294093091213 0.0675463246647507 0.190397102786355 GO:0031683 G-protein beta/gamma-subunit complex binding 7/3194 22/18639 0.318181818181818 1.85679114248306 0.0685130330207753 0.192711126922266 GO:0015036 disulfide oxidoreductase activity 11/3194 40/18639 0.275 1.60479805886036 0.0687256997694799 0.192898885552553 GO:0070273 phosphatidylinositol-4-phosphate binding 9/3194 31/18639 0.290322580645161 1.69421495950068 0.0705764532557411 0.197673879669682 GO:0031491 nucleosome binding 18/3194 74/18639 0.243243243243243 1.41947739850057 0.0725778957295073 0.202849848106572 GO:0000900 mRNA regulatory element binding translation repressor activity 6/3194 18/18639 0.333333333333333 1.94520976831559 0.0729876120735329 0.203564605825339 GO:0015605 organophosphate ester transmembrane transporter activity 13/3194 50/18639 0.26 1.51726361928616 0.0748599480967548 0.205017302395578 GO:0005484 SNAP receptor activity 10/3194 36/18639 0.277777777777778 1.62100814026299 0.0759137996552134 0.205017302395578 GO:0003680 minor groove of adenine-thymine-rich DNA binding 4/3194 10/18639 0.4 2.33425172197871 0.0759432468296228 0.205017302395578 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 4/3194 10/18639 0.4 2.33425172197871 0.0759432468296228 0.205017302395578 GO:0008641 ubiquitin-like modifier activating enzyme activity 4/3194 10/18639 0.4 2.33425172197871 0.0759432468296228 0.205017302395578 GO:0015658 branched-chain amino acid transmembrane transporter activity 4/3194 10/18639 0.4 2.33425172197871 0.0759432468296228 0.205017302395578 GO:0016427 tRNA (cytidine) methyltransferase activity 4/3194 10/18639 0.4 2.33425172197871 0.0759432468296228 0.205017302395578 GO:0031996 thioesterase binding 4/3194 10/18639 0.4 2.33425172197871 0.0759432468296228 0.205017302395578 GO:0043422 protein kinase B binding 4/3194 10/18639 0.4 2.33425172197871 0.0759432468296228 0.205017302395578 GO:0050308 sugar-phosphatase activity 4/3194 10/18639 0.4 2.33425172197871 0.0759432468296228 0.205017302395578 GO:0050815 phosphoserine residue binding 4/3194 10/18639 0.4 2.33425172197871 0.0759432468296228 0.205017302395578 GO:0070513 death domain binding 4/3194 10/18639 0.4 2.33425172197871 0.0759432468296228 0.205017302395578 GO:0004705 JUN kinase activity 5/3194 14/18639 0.357142857142857 2.08415332319528 0.0761448528564514 0.205017302395578 GO:0008474 palmitoyl-(protein) hydrolase activity 5/3194 14/18639 0.357142857142857 2.08415332319528 0.0761448528564514 0.205017302395578 GO:0070742 C2H2 zinc finger domain binding 5/3194 14/18639 0.357142857142857 2.08415332319528 0.0761448528564514 0.205017302395578 GO:0098599 palmitoyl hydrolase activity 5/3194 14/18639 0.357142857142857 2.08415332319528 0.0761448528564514 0.205017302395578 GO:1901474 azole transmembrane transporter activity 5/3194 14/18639 0.357142857142857 2.08415332319528 0.0761448528564514 0.205017302395578 GO:0008320 protein transmembrane transporter activity 8/3194 27/18639 0.296296296296296 1.72907534961386 0.0773379881729248 0.207806545456517 GO:0046982 protein heterodimerization activity 74/3194 369/18639 0.200542005420054 1.17028880370206 0.0779812483755688 0.209109960147063 GO:0015175 neutral L-amino acid transmembrane transporter activity 11/3194 41/18639 0.268292682926829 1.5656566427906 0.0799875670894938 0.214055796947998 GO:0016278 lysine N-methyltransferase activity 17/3194 70/18639 0.242857142857143 1.41722425977279 0.0803495048990585 0.214589990861728 GO:0004518 nuclease activity 44/3194 209/18639 0.210526315789474 1.22855353788353 0.0805637530818693 0.214728390270628 GO:0071813 lipoprotein particle binding 9/3194 32/18639 0.28125 1.64127074201628 0.0838860890231401 0.222685561623677 GO:0071814 protein-lipid complex binding 9/3194 32/18639 0.28125 1.64127074201628 0.0838860890231401 0.222685561623677 GO:0000295 adenine nucleotide transmembrane transporter activity 7/3194 23/18639 0.304347826086957 1.77606109280989 0.0844979400473408 0.223860274033235 GO:0008514 organic anion transmembrane transporter activity 55/3194 269/18639 0.204460966542751 1.19315840807462 0.0875111306204963 0.231379429360592 GO:0043394 proteoglycan binding 10/3194 37/18639 0.27027027027027 1.57719710944507 0.0887460720033215 0.233738704622731 GO:0030246 carbohydrate binding 57/3194 280/18639 0.203571428571429 1.18796739422131 0.0887570572773155 0.233738704622731 GO:0050660 flavin adenine dinucleotide binding 20/3194 86/18639 0.232558139534884 1.35712309417367 0.0894151944344707 0.235003751575289 GO:0003774 cytoskeletal motor activity 33/3194 153/18639 0.215686274509804 1.25866514420421 0.0906311394709819 0.237076277155991 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 27/3194 122/18639 0.221311475409836 1.29149173142265 0.0916509767071629 0.237076277155991 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 6/3194 19/18639 0.315789473684211 1.8428303068253 0.0918177412283415 0.237076277155991 GO:0005346 purine ribonucleotide transmembrane transporter activity 6/3194 19/18639 0.315789473684211 1.8428303068253 0.0918177412283415 0.237076277155991 GO:0022821 solute:potassium antiporter activity 6/3194 19/18639 0.315789473684211 1.8428303068253 0.0918177412283415 0.237076277155991 GO:0031420 alkali metal ion binding 6/3194 19/18639 0.315789473684211 1.8428303068253 0.0918177412283415 0.237076277155991 GO:0042577 lipid phosphatase activity 6/3194 19/18639 0.315789473684211 1.8428303068253 0.0918177412283415 0.237076277155991 GO:0042834 peptidoglycan binding 6/3194 19/18639 0.315789473684211 1.8428303068253 0.0918177412283415 0.237076277155991 GO:0097001 ceramide binding 6/3194 19/18639 0.315789473684211 1.8428303068253 0.0918177412283415 0.237076277155991 GO:0046625 sphingolipid binding 8/3194 28/18639 0.285714285714286 1.66732265855622 0.0927085232963494 0.238909683816323 GO:0019956 chemokine binding 9/3194 33/18639 0.272727272727273 1.59153526498548 0.0985946182723352 0.250955376150398 GO:0140416 transcription regulator inhibitor activity 9/3194 33/18639 0.272727272727273 1.59153526498548 0.0985946182723352 0.250955376150398 GO:0005402 carbohydrate:monoatomic cation symporter activity 5/3194 15/18639 0.333333333333333 1.94520976831559 0.0987116456869948 0.250955376150398 GO:0034483 heparan sulfate sulfotransferase activity 5/3194 15/18639 0.333333333333333 1.94520976831559 0.0987116456869948 0.250955376150398 GO:0047372 monoacylglycerol lipase activity 5/3194 15/18639 0.333333333333333 1.94520976831559 0.0987116456869948 0.250955376150398 GO:0141050 histone H3K deacetylase activity 5/3194 15/18639 0.333333333333333 1.94520976831559 0.0987116456869948 0.250955376150398 GO:0141051 histone H4K deacetylase activity 5/3194 15/18639 0.333333333333333 1.94520976831559 0.0987116456869948 0.250955376150398 GO:0004622 lysophospholipase activity 7/3194 24/18639 0.291666666666667 1.70205854727614 0.102422167156836 0.256708694789778 GO:0005315 phosphate transmembrane transporter activity 7/3194 24/18639 0.291666666666667 1.70205854727614 0.102422167156836 0.256708694789778 GO:0050699 WW domain binding 7/3194 24/18639 0.291666666666667 1.70205854727614 0.102422167156836 0.256708694789778 GO:0070300 phosphatidic acid binding 7/3194 24/18639 0.291666666666667 1.70205854727614 0.102422167156836 0.256708694789778 GO:0140033 acetylation-dependent protein binding 7/3194 24/18639 0.291666666666667 1.70205854727614 0.102422167156836 0.256708694789778 GO:0042162 telomeric DNA binding 10/3194 38/18639 0.263157894736842 1.53569192235441 0.102800580499597 0.256708694789778 GO:0002162 dystroglycan binding 4/3194 11/18639 0.363636363636364 2.12204701998065 0.103693224673027 0.256708694789778 GO:0005114 type II transforming growth factor beta receptor binding 4/3194 11/18639 0.363636363636364 2.12204701998065 0.103693224673027 0.256708694789778 GO:0008526 phosphatidylinositol transfer activity 4/3194 11/18639 0.363636363636364 2.12204701998065 0.103693224673027 0.256708694789778 GO:0019203 carbohydrate phosphatase activity 4/3194 11/18639 0.363636363636364 2.12204701998065 0.103693224673027 0.256708694789778 GO:0047676 arachidonate-CoA ligase activity 4/3194 11/18639 0.363636363636364 2.12204701998065 0.103693224673027 0.256708694789778 GO:0048185 activin binding 4/3194 11/18639 0.363636363636364 2.12204701998065 0.103693224673027 0.256708694789778 GO:0050786 RAGE receptor binding 4/3194 11/18639 0.363636363636364 2.12204701998065 0.103693224673027 0.256708694789778 GO:0070990 snRNP binding 4/3194 11/18639 0.363636363636364 2.12204701998065 0.103693224673027 0.256708694789778 GO:0008170 N-methyltransferase activity 22/3194 98/18639 0.224489795918367 1.31003923172275 0.105468205843694 0.260614893692268 GO:0005178 integrin binding 34/3194 161/18639 0.211180124223602 1.23236892154155 0.109097187045465 0.269079256108404 GO:0106222 lncRNA binding 8/3194 29/18639 0.275862068965517 1.60982877377842 0.109694213069697 0.2700479509835 GO:0001614 purinergic nucleotide receptor activity 6/3194 20/18639 0.3 1.75068879148403 0.112997519152321 0.277147904117567 GO:0016502 nucleotide receptor activity 6/3194 20/18639 0.3 1.75068879148403 0.112997519152321 0.277147904117567 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 35/3194 167/18639 0.209580838323353 1.22303608187507 0.114150668315705 0.279457747246968 GO:0030332 cyclin binding 9/3194 34/18639 0.264705882352941 1.54472540425062 0.114686346908712 0.279733119212762 GO:0090482 vitamin transmembrane transporter activity 9/3194 34/18639 0.264705882352941 1.54472540425062 0.114686346908712 0.279733119212762 GO:0061134 peptidase regulator activity 46/3194 226/18639 0.20353982300885 1.18778295587412 0.115929692369649 0.282245033725003 GO:0016776 phosphotransferase activity, phosphate group as acceptor 10/3194 39/18639 0.256410256410256 1.49631520639661 0.118064456903181 0.286913992694862 GO:0004527 exonuclease activity 19/3194 84/18639 0.226190476190476 1.31996377135701 0.118717043587242 0.287970516738228 GO:0043014 alpha-tubulin binding 11/3194 44/18639 0.25 1.45890732623669 0.120267808344821 0.291197880278119 GO:0016279 protein-lysine N-methyltransferase activity 16/3194 69/18639 0.231884057971014 1.35318940404563 0.121635156557268 0.293970158992154 GO:0005537 D-mannose binding 7/3194 25/18639 0.28 1.6339762053851 0.122229489269491 0.294330391282817 GO:0017025 TBP-class protein binding 7/3194 25/18639 0.28 1.6339762053851 0.122229489269491 0.294330391282817 GO:0004707 MAP kinase activity 5/3194 16/18639 0.3125 1.82363415779587 0.124215280830756 0.296412637650288 GO:0005149 interleukin-1 receptor binding 5/3194 16/18639 0.3125 1.82363415779587 0.124215280830756 0.296412637650288 GO:0034450 ubiquitin-ubiquitin ligase activity 5/3194 16/18639 0.3125 1.82363415779587 0.124215280830756 0.296412637650288 GO:0097027 ubiquitin-protein transferase activator activity 5/3194 16/18639 0.3125 1.82363415779587 0.124215280830756 0.296412637650288 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 5/3194 16/18639 0.3125 1.82363415779587 0.124215280830756 0.296412637650288 GO:0008276 protein methyltransferase activity 21/3194 95/18639 0.221052631578947 1.28998121477771 0.126130962405497 0.30044167981994 GO:0035925 mRNA 3'-UTR AU-rich region binding 8/3194 30/18639 0.266666666666667 1.55616781465247 0.128251272062563 0.304942772781849 GO:0005078 MAP-kinase scaffold activity 4/3194 12/18639 0.333333333333333 1.94520976831559 0.135315283787069 0.317175186465436 GO:0005527 macrolide binding 4/3194 12/18639 0.333333333333333 1.94520976831559 0.135315283787069 0.317175186465436 GO:0015368 calcium:monoatomic cation antiporter activity 4/3194 12/18639 0.333333333333333 1.94520976831559 0.135315283787069 0.317175186465436 GO:0016840 carbon-nitrogen lyase activity 4/3194 12/18639 0.333333333333333 1.94520976831559 0.135315283787069 0.317175186465436 GO:0070008 serine-type exopeptidase activity 4/3194 12/18639 0.333333333333333 1.94520976831559 0.135315283787069 0.317175186465436 GO:0070410 co-SMAD binding 4/3194 12/18639 0.333333333333333 1.94520976831559 0.135315283787069 0.317175186465436 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 4/3194 12/18639 0.333333333333333 1.94520976831559 0.135315283787069 0.317175186465436 GO:1990817 poly(A) RNA polymerase activity 4/3194 12/18639 0.333333333333333 1.94520976831559 0.135315283787069 0.317175186465436 GO:0005123 death receptor binding 6/3194 21/18639 0.285714285714286 1.66732265855622 0.136401937803157 0.318030620415826 GO:0010314 phosphatidylinositol-5-phosphate binding 6/3194 21/18639 0.285714285714286 1.66732265855622 0.136401937803157 0.318030620415826 GO:0072542 protein phosphatase activator activity 6/3194 21/18639 0.285714285714286 1.66732265855622 0.136401937803157 0.318030620415826 GO:0015216 purine nucleotide transmembrane transporter activity 7/3194 26/18639 0.269230769230769 1.57113096671644 0.143829498758098 0.334758093940503 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 92/3194 484/18639 0.190082644628099 1.10925185135352 0.147901232907466 0.343629929531933 GO:0070325 lipoprotein particle receptor binding 8/3194 31/18639 0.258064516129032 1.50596885288949 0.148312078604066 0.343979943709781 GO:0016409 palmitoyltransferase activity 9/3194 36/18639 0.25 1.45890732623669 0.150864745492531 0.349287554362743 GO:0001530 lipopolysaccharide binding 10/3194 41/18639 0.24390243902439 1.42332422071873 0.152098819665464 0.349787742158405 GO:0008484 sulfuric ester hydrolase activity 5/3194 17/18639 0.294117647058824 1.71636156027846 0.152397142314499 0.349787742158405 GO:0032183 SUMO binding 5/3194 17/18639 0.294117647058824 1.71636156027846 0.152397142314499 0.349787742158405 GO:0036041 long-chain fatty acid binding 5/3194 17/18639 0.294117647058824 1.71636156027846 0.152397142314499 0.349787742158405 GO:0030291 protein serine/threonine kinase inhibitor activity 11/3194 46/18639 0.239130434782609 1.39547657292206 0.152403736371589 0.349787742158405 GO:0001216 DNA-binding transcription activator activity 93/3194 491/18639 0.189409368635438 1.10532286224043 0.155111604901898 0.355385687487538 GO:0004407 histone deacetylase activity 6/3194 22/18639 0.272727272727273 1.59153526498548 0.16186027709655 0.368929804002826 GO:0015377 chloride:monoatomic cation symporter activity 6/3194 22/18639 0.272727272727273 1.59153526498548 0.16186027709655 0.368929804002826 GO:0033558 protein lysine deacetylase activity 6/3194 22/18639 0.272727272727273 1.59153526498548 0.16186027709655 0.368929804002826 GO:0140098 catalytic activity, acting on RNA 74/3194 387/18639 0.191214470284238 1.11585676632057 0.163521011469015 0.372073626784919 GO:0044325 transmembrane transporter binding 28/3194 136/18639 0.205882352941176 1.20145309219492 0.168318095701307 0.379561968890935 GO:0030165 PDZ domain binding 18/3194 83/18639 0.216867469879518 1.26555816251858 0.16838420928151 0.379561968890935 GO:0030515 snoRNA binding 8/3194 32/18639 0.25 1.45890732623669 0.169787408464375 0.379561968890935 GO:0008035 high-density lipoprotein particle binding 4/3194 13/18639 0.307692307692308 1.79557824767593 0.170257373337613 0.379561968890935 GO:0015651 quaternary ammonium group transmembrane transporter activity 4/3194 13/18639 0.307692307692308 1.79557824767593 0.170257373337613 0.379561968890935 GO:0035673 oligopeptide transmembrane transporter activity 4/3194 13/18639 0.307692307692308 1.79557824767593 0.170257373337613 0.379561968890935 GO:0051011 microtubule minus-end binding 4/3194 13/18639 0.307692307692308 1.79557824767593 0.170257373337613 0.379561968890935 GO:0070123 transforming growth factor beta receptor activity, type III 4/3194 13/18639 0.307692307692308 1.79557824767593 0.170257373337613 0.379561968890935 GO:0071714 icosanoid transmembrane transporter activity 4/3194 13/18639 0.307692307692308 1.79557824767593 0.170257373337613 0.379561968890935 GO:0089720 caspase binding 4/3194 13/18639 0.307692307692308 1.79557824767593 0.170257373337613 0.379561968890935 GO:0097157 pre-mRNA intronic binding 4/3194 13/18639 0.307692307692308 1.79557824767593 0.170257373337613 0.379561968890935 GO:0140410 monoatomic cation:bicarbonate symporter activity 4/3194 13/18639 0.307692307692308 1.79557824767593 0.170257373337613 0.379561968890935 GO:0016757 glycosyltransferase activity 52/3194 267/18639 0.194756554307116 1.13652705564506 0.172995837993859 0.385017673110913 GO:0016410 N-acyltransferase activity 20/3194 94/18639 0.212765957446809 1.24162325637165 0.174717282146252 0.388195373104782 GO:0008525 phosphatidylcholine transporter activity 5/3194 18/18639 0.277777777777778 1.62100814026299 0.182939269330255 0.40374910526644 GO:0015172 acidic amino acid transmembrane transporter activity 5/3194 18/18639 0.277777777777778 1.62100814026299 0.182939269330255 0.40374910526644 GO:0050811 GABA receptor binding 5/3194 18/18639 0.277777777777778 1.62100814026299 0.182939269330255 0.40374910526644 GO:1990381 ubiquitin-specific protease binding 5/3194 18/18639 0.277777777777778 1.62100814026299 0.182939269330255 0.40374910526644 GO:0070577 lysine-acetylated histone binding 6/3194 23/18639 0.260869565217391 1.52233807955133 0.189164631349212 0.416792737739431 GO:0008375 acetylglucosaminyltransferase activity 10/3194 43/18639 0.232558139534884 1.35712309417367 0.19047631385816 0.418288516479215 GO:0048156 tau protein binding 10/3194 43/18639 0.232558139534884 1.35712309417367 0.19047631385816 0.418288516479215 GO:0097718 disordered domain specific binding 7/3194 28/18639 0.25 1.45890732623669 0.191899195518429 0.42071432251304 GO:0030296 protein tyrosine kinase activator activity 8/3194 33/18639 0.242424242424242 1.41469801332043 0.192569101325827 0.421484026411827 GO:0048306 calcium-dependent protein binding 17/3194 80/18639 0.2125 1.24007122730119 0.20032225149829 0.437728952860726 GO:0017069 snRNA binding 12/3194 54/18639 0.222222222222222 1.29680651221039 0.204251636990482 0.445578653632702 GO:0008195 phosphatidate phosphatase activity 4/3194 14/18639 0.285714285714286 1.66732265855622 0.207902381530078 0.447633466421437 GO:0015386 potassium:proton antiporter activity 4/3194 14/18639 0.285714285714286 1.66732265855622 0.207902381530078 0.447633466421437 GO:0016530 metallochaperone activity 4/3194 14/18639 0.285714285714286 1.66732265855622 0.207902381530078 0.447633466421437 GO:0019992 diacylglycerol binding 4/3194 14/18639 0.285714285714286 1.66732265855622 0.207902381530078 0.447633466421437 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 4/3194 14/18639 0.285714285714286 1.66732265855622 0.207902381530078 0.447633466421437 GO:0044548 S100 protein binding 4/3194 14/18639 0.285714285714286 1.66732265855622 0.207902381530078 0.447633466421437 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 4/3194 14/18639 0.285714285714286 1.66732265855622 0.207902381530078 0.447633466421437 GO:0098847 sequence-specific single stranded DNA binding 4/3194 14/18639 0.285714285714286 1.66732265855622 0.207902381530078 0.447633466421437 GO:0038024 cargo receptor activity 14/3194 65/18639 0.215384615384615 1.25690477337315 0.213837113459496 0.459499097470637 GO:0000217 DNA secondary structure binding 9/3194 39/18639 0.230769230769231 1.34668368575695 0.214108505326711 0.459499097470637 GO:0034987 immunoglobulin receptor binding 5/3194 19/18639 0.263157894736842 1.53569192235441 0.215482672223796 0.460206934862454 GO:0042800 histone H3K4 methyltransferase activity 5/3194 19/18639 0.263157894736842 1.53569192235441 0.215482672223796 0.460206934862454 GO:0050145 nucleoside monophosphate kinase activity 5/3194 19/18639 0.263157894736842 1.53569192235441 0.215482672223796 0.460206934862454 GO:0008376 acetylgalactosaminyltransferase activity 8/3194 34/18639 0.235294117647059 1.37308924822277 0.216533025761862 0.460906672504487 GO:0015035 protein-disulfide reductase activity 8/3194 34/18639 0.235294117647059 1.37308924822277 0.216533025761862 0.460906672504487 GO:0001091 RNA polymerase II general transcription initiation factor binding 6/3194 24/18639 0.25 1.45890732623669 0.218078786080004 0.460906672504487 GO:0019957 C-C chemokine binding 6/3194 24/18639 0.25 1.45890732623669 0.218078786080004 0.460906672504487 GO:0048027 mRNA 5'-UTR binding 6/3194 24/18639 0.25 1.45890732623669 0.218078786080004 0.460906672504487 GO:0050431 transforming growth factor beta binding 6/3194 24/18639 0.25 1.45890732623669 0.218078786080004 0.460906672504487 GO:0005496 steroid binding 22/3194 108/18639 0.203703703703704 1.18873930285953 0.218250814665514 0.460906672504487 GO:0043178 alcohol binding 19/3194 92/18639 0.206521739130435 1.20518431297814 0.220214192124882 0.4643112631405 GO:0016798 hydrolase activity, acting on glycosyl bonds 26/3194 130/18639 0.2 1.16712586098936 0.222485637479346 0.468353523483591 GO:0008081 phosphoric diester hydrolase activity 18/3194 87/18639 0.206896551724138 1.20737158033382 0.225652609995111 0.474265103996084 GO:0015026 coreceptor activity 13/3194 61/18639 0.213114754098361 1.24365870433292 0.237063488017726 0.483204429352158 GO:0015144 carbohydrate transmembrane transporter activity 9/3194 40/18639 0.225 1.31301659361302 0.237217542888346 0.483204429352158 GO:0004955 prostaglandin receptor activity 3/3194 10/18639 0.3 1.75068879148403 0.237947113092477 0.483204429352158 GO:0005031 tumor necrosis factor receptor activity 3/3194 10/18639 0.3 1.75068879148403 0.237947113092477 0.483204429352158 GO:0005131 growth hormone receptor binding 3/3194 10/18639 0.3 1.75068879148403 0.237947113092477 0.483204429352158 GO:0005522 profilin binding 3/3194 10/18639 0.3 1.75068879148403 0.237947113092477 0.483204429352158 GO:0015643 toxic substance binding 3/3194 10/18639 0.3 1.75068879148403 0.237947113092477 0.483204429352158 GO:0015924 mannosyl-oligosaccharide mannosidase activity 3/3194 10/18639 0.3 1.75068879148403 0.237947113092477 0.483204429352158 GO:0016303 1-phosphatidylinositol-3-kinase activity 3/3194 10/18639 0.3 1.75068879148403 0.237947113092477 0.483204429352158 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 3/3194 10/18639 0.3 1.75068879148403 0.237947113092477 0.483204429352158 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 3/3194 10/18639 0.3 1.75068879148403 0.237947113092477 0.483204429352158 GO:0030957 Tat protein binding 3/3194 10/18639 0.3 1.75068879148403 0.237947113092477 0.483204429352158 GO:0031434 mitogen-activated protein kinase kinase binding 3/3194 10/18639 0.3 1.75068879148403 0.237947113092477 0.483204429352158 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 3/3194 10/18639 0.3 1.75068879148403 0.237947113092477 0.483204429352158 GO:0035256 G protein-coupled glutamate receptor binding 3/3194 10/18639 0.3 1.75068879148403 0.237947113092477 0.483204429352158 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 3/3194 10/18639 0.3 1.75068879148403 0.237947113092477 0.483204429352158 GO:0043208 glycosphingolipid binding 3/3194 10/18639 0.3 1.75068879148403 0.237947113092477 0.483204429352158 GO:0051880 G-quadruplex DNA binding 3/3194 10/18639 0.3 1.75068879148403 0.237947113092477 0.483204429352158 GO:0071723 lipopeptide binding 3/3194 10/18639 0.3 1.75068879148403 0.237947113092477 0.483204429352158 GO:0098505 G-rich strand telomeric DNA binding 3/3194 10/18639 0.3 1.75068879148403 0.237947113092477 0.483204429352158 GO:0140999 histone H3K4 trimethyltransferase activity 3/3194 10/18639 0.3 1.75068879148403 0.237947113092477 0.483204429352158 GO:1990757 ubiquitin ligase activator activity 3/3194 10/18639 0.3 1.75068879148403 0.237947113092477 0.483204429352158 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 35/3194 181/18639 0.193370165745856 1.12843660592893 0.241456454473087 0.489578884683161 GO:0019212 phosphatase inhibitor activity 12/3194 56/18639 0.214285714285714 1.25049199391717 0.242859728768428 0.491670078762423 GO:0000774 adenyl-nucleotide exchange factor activity 4/3194 15/18639 0.266666666666667 1.55616781465247 0.247608103654835 0.497446536767029 GO:0004467 long-chain fatty acid-CoA ligase activity 4/3194 15/18639 0.266666666666667 1.55616781465247 0.247608103654835 0.497446536767029 GO:0050700 CARD domain binding 4/3194 15/18639 0.266666666666667 1.55616781465247 0.247608103654835 0.497446536767029 GO:0015296 monoatomic anion:monoatomic cation symporter activity 6/3194 25/18639 0.24 1.40055103318723 0.248346985072798 0.497446536767029 GO:0015662 P-type ion transporter activity 6/3194 25/18639 0.24 1.40055103318723 0.248346985072798 0.497446536767029 GO:0019211 phosphatase activator activity 6/3194 25/18639 0.24 1.40055103318723 0.248346985072798 0.497446536767029 GO:0140358 P-type transmembrane transporter activity 6/3194 25/18639 0.24 1.40055103318723 0.248346985072798 0.497446536767029 GO:0000339 RNA cap binding 5/3194 20/18639 0.25 1.45890732623669 0.249644389914288 0.498534567170224 GO:0043024 ribosomal small subunit binding 5/3194 20/18639 0.25 1.45890732623669 0.249644389914288 0.498534567170224 GO:0008168 methyltransferase activity 39/3194 204/18639 0.191176470588235 1.115635014181 0.25047772774307 0.499444277641537 GO:0030276 clathrin binding 10/3194 46/18639 0.217391304347826 1.26861506629278 0.254928254839807 0.507552941111784 GO:0015932 nucleobase-containing compound transmembrane transporter activity 12/3194 57/18639 0.210526315789474 1.22855353788353 0.263120833445126 0.523076303480386 GO:0008013 beta-catenin binding 21/3194 106/18639 0.19811320754717 1.15611523965927 0.267170951808363 0.530330327763748 GO:0043177 organic acid binding 36/3194 189/18639 0.19047619047619 1.11154843903748 0.26860242060363 0.532372413850074 GO:0005452 solute:inorganic anion antiporter activity 7/3194 31/18639 0.225806451612903 1.3177227462783 0.273700512253461 0.54166478622616 GO:0061135 endopeptidase regulator activity 35/3194 184/18639 0.190217391304348 1.11003818300618 0.275043043410352 0.54350807681388 GO:0061749 forked DNA-dependent helicase activity 10/3194 47/18639 0.212765957446809 1.24162325637165 0.277892437888597 0.544574888569439 GO:1990518 single-stranded 3'-5' DNA helicase activity 10/3194 47/18639 0.212765957446809 1.24162325637165 0.277892437888597 0.544574888569439 GO:0003684 damaged DNA binding 15/3194 74/18639 0.202702702702703 1.18289783208381 0.279251568398991 0.544574888569439 GO:0001637 G protein-coupled chemoattractant receptor activity 6/3194 26/18639 0.230769230769231 1.34668368575695 0.279702230967208 0.544574888569439 GO:0004950 chemokine receptor activity 6/3194 26/18639 0.230769230769231 1.34668368575695 0.279702230967208 0.544574888569439 GO:0008198 ferrous iron binding 6/3194 26/18639 0.230769230769231 1.34668368575695 0.279702230967208 0.544574888569439 GO:0019865 immunoglobulin binding 6/3194 26/18639 0.230769230769231 1.34668368575695 0.279702230967208 0.544574888569439 GO:0030247 polysaccharide binding 6/3194 26/18639 0.230769230769231 1.34668368575695 0.279702230967208 0.544574888569439 GO:0034237 protein kinase A regulatory subunit binding 6/3194 26/18639 0.230769230769231 1.34668368575695 0.279702230967208 0.544574888569439 GO:0120014 phospholipid transfer activity 6/3194 26/18639 0.230769230769231 1.34668368575695 0.279702230967208 0.544574888569439 GO:0008373 sialyltransferase activity 5/3194 21/18639 0.238095238095238 1.38943554879685 0.285032656199016 0.546866786470157 GO:0031492 nucleosomal DNA binding 9/3194 42/18639 0.214285714285714 1.25049199391717 0.285806704754882 0.546866786470157 GO:0004954 prostanoid receptor activity 3/3194 11/18639 0.272727272727273 1.59153526498548 0.288292321249771 0.546866786470157 GO:0008199 ferric iron binding 3/3194 11/18639 0.272727272727273 1.59153526498548 0.288292321249771 0.546866786470157 GO:0016176 superoxide-generating NADPH oxidase activator activity 3/3194 11/18639 0.272727272727273 1.59153526498548 0.288292321249771 0.546866786470157 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 3/3194 11/18639 0.272727272727273 1.59153526498548 0.288292321249771 0.546866786470157 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 3/3194 11/18639 0.272727272727273 1.59153526498548 0.288292321249771 0.546866786470157 GO:0032050 clathrin heavy chain binding 3/3194 11/18639 0.272727272727273 1.59153526498548 0.288292321249771 0.546866786470157 GO:0032794 GTPase activating protein binding 3/3194 11/18639 0.272727272727273 1.59153526498548 0.288292321249771 0.546866786470157 GO:0034056 estrogen response element binding 3/3194 11/18639 0.272727272727273 1.59153526498548 0.288292321249771 0.546866786470157 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 3/3194 11/18639 0.272727272727273 1.59153526498548 0.288292321249771 0.546866786470157 GO:0034713 type I transforming growth factor beta receptor binding 3/3194 11/18639 0.272727272727273 1.59153526498548 0.288292321249771 0.546866786470157 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 3/3194 11/18639 0.272727272727273 1.59153526498548 0.288292321249771 0.546866786470157 GO:0070697 activin receptor binding 3/3194 11/18639 0.272727272727273 1.59153526498548 0.288292321249771 0.546866786470157 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 3/3194 11/18639 0.272727272727273 1.59153526498548 0.288292321249771 0.546866786470157 GO:0005024 transforming growth factor beta receptor activity 4/3194 16/18639 0.25 1.45890732623669 0.288739044596195 0.546866786470157 GO:0008142 oxysterol binding 4/3194 16/18639 0.25 1.45890732623669 0.288739044596195 0.546866786470157 GO:0015378 sodium:chloride symporter activity 4/3194 16/18639 0.25 1.45890732623669 0.288739044596195 0.546866786470157 GO:0015923 mannosidase activity 4/3194 16/18639 0.25 1.45890732623669 0.288739044596195 0.546866786470157 GO:0072341 modified amino acid binding 18/3194 91/18639 0.197802197802198 1.15430030207738 0.290126736800722 0.548708935694641 GO:0004864 protein phosphatase inhibitor activity 11/3194 53/18639 0.207547169811321 1.21116834630971 0.292418867773919 0.549897216496617 GO:0005544 calcium-dependent phospholipid binding 11/3194 53/18639 0.207547169811321 1.21116834630971 0.292418867773919 0.549897216496617 GO:0016251 RNA polymerase II general transcription initiation factor activity 11/3194 53/18639 0.207547169811321 1.21116834630971 0.292418867773919 0.549897216496617 GO:0051018 protein kinase A binding 11/3194 53/18639 0.207547169811321 1.21116834630971 0.292418867773919 0.549897216496617 GO:0019213 deacetylase activity 8/3194 37/18639 0.216216216216216 1.26175768755606 0.294103472212281 0.550715000374839 GO:0042805 actinin binding 8/3194 37/18639 0.216216216216216 1.26175768755606 0.294103472212281 0.550715000374839 GO:0070001 aspartic-type peptidase activity 8/3194 37/18639 0.216216216216216 1.26175768755606 0.294103472212281 0.550715000374839 GO:0044183 protein folding chaperone 15/3194 75/18639 0.2 1.16712586098936 0.297880235061368 0.556998119874298 GO:0009378 four-way junction helicase activity 10/3194 48/18639 0.208333333333333 1.21575610519724 0.301431297589912 0.561256585089948 GO:0036121 double-stranded DNA helicase activity 10/3194 48/18639 0.208333333333333 1.21575610519724 0.301431297589912 0.561256585089948 GO:0043138 3'-5' DNA helicase activity 10/3194 48/18639 0.208333333333333 1.21575610519724 0.301431297589912 0.561256585089948 GO:0031369 translation initiation factor binding 7/3194 32/18639 0.21875 1.27654391045711 0.302796181314405 0.563004995355335 GO:0036002 pre-mRNA binding 12/3194 59/18639 0.203389830508475 1.18690765524341 0.305207310275766 0.566691101382813 GO:0016741 transferase activity, transferring one-carbon groups 40/3194 215/18639 0.186046511627907 1.08569847533893 0.309061817797246 0.573043089941037 GO:0031406 carboxylic acid binding 35/3194 187/18639 0.18716577540107 1.09223008381357 0.310339582264187 0.574606341391114 GO:0050661 NADP binding 11/3194 54/18639 0.203703703703704 1.18873930285953 0.314973275648752 0.582370168402308 GO:0160215 deacylase activity 13/3194 65/18639 0.2 1.16712586098936 0.316598812657095 0.584228328216361 GO:0017022 myosin binding 15/3194 76/18639 0.197368421052632 1.15176894176581 0.316862111445636 0.584228328216361 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 5/3194 22/18639 0.227272727272727 1.3262793874879 0.321259826523271 0.5900267157363 GO:0016881 acid-amino acid ligase activity 5/3194 22/18639 0.227272727272727 1.3262793874879 0.321259826523271 0.5900267157363 GO:0042887 amide transmembrane transporter activity 8/3194 38/18639 0.210526315789474 1.22855353788353 0.321345866361676 0.5900267157363 GO:0035254 glutamate receptor binding 10/3194 49/18639 0.204081632653061 1.19094475611159 0.325440480621779 0.596716110099849 GO:0051082 unfolded protein binding 23/3194 121/18639 0.190082644628099 1.10925185135352 0.326922816535153 0.598603827506194 GO:0004029 aldehyde dehydrogenase (NAD+) activity 4/3194 17/18639 0.235294117647059 1.37308924822277 0.330690399144409 0.598844232132747 GO:0004659 prenyltransferase activity 4/3194 17/18639 0.235294117647059 1.37308924822277 0.330690399144409 0.598844232132747 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 4/3194 17/18639 0.235294117647059 1.37308924822277 0.330690399144409 0.598844232132747 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 4/3194 17/18639 0.235294117647059 1.37308924822277 0.330690399144409 0.598844232132747 GO:0038191 neuropilin binding 4/3194 17/18639 0.235294117647059 1.37308924822277 0.330690399144409 0.598844232132747 GO:0070402 NADPH binding 4/3194 17/18639 0.235294117647059 1.37308924822277 0.330690399144409 0.598844232132747 GO:0019205 nucleobase-containing compound kinase activity 9/3194 44/18639 0.204545454545455 1.19365144873911 0.336733737455133 0.598844232132747 GO:0000340 RNA 7-methylguanosine cap binding 3/3194 12/18639 0.25 1.45890732623669 0.339284667070671 0.598844232132747 GO:0004126 cytidine deaminase activity 3/3194 12/18639 0.25 1.45890732623669 0.339284667070671 0.598844232132747 GO:0004859 phospholipase inhibitor activity 3/3194 12/18639 0.25 1.45890732623669 0.339284667070671 0.598844232132747 GO:0005025 transforming growth factor beta receptor activity, type I 3/3194 12/18639 0.25 1.45890732623669 0.339284667070671 0.598844232132747 GO:0005026 transforming growth factor beta receptor activity, type II 3/3194 12/18639 0.25 1.45890732623669 0.339284667070671 0.598844232132747 GO:0015132 prostaglandin transmembrane transporter activity 3/3194 12/18639 0.25 1.45890732623669 0.339284667070671 0.598844232132747 GO:0015269 calcium-activated potassium channel activity 3/3194 12/18639 0.25 1.45890732623669 0.339284667070671 0.598844232132747 GO:0016273 arginine N-methyltransferase activity 3/3194 12/18639 0.25 1.45890732623669 0.339284667070671 0.598844232132747 GO:0016274 protein-arginine N-methyltransferase activity 3/3194 12/18639 0.25 1.45890732623669 0.339284667070671 0.598844232132747 GO:0016361 activin receptor activity, type I 3/3194 12/18639 0.25 1.45890732623669 0.339284667070671 0.598844232132747 GO:0016362 activin receptor activity, type II 3/3194 12/18639 0.25 1.45890732623669 0.339284667070671 0.598844232132747 GO:0016423 tRNA (guanine) methyltransferase activity 3/3194 12/18639 0.25 1.45890732623669 0.339284667070671 0.598844232132747 GO:0017002 activin receptor activity 3/3194 12/18639 0.25 1.45890732623669 0.339284667070671 0.598844232132747 GO:0031543 peptidyl-proline dioxygenase activity 3/3194 12/18639 0.25 1.45890732623669 0.339284667070671 0.598844232132747 GO:0034452 dynactin binding 3/3194 12/18639 0.25 1.45890732623669 0.339284667070671 0.598844232132747 GO:0035014 phosphatidylinositol 3-kinase regulator activity 3/3194 12/18639 0.25 1.45890732623669 0.339284667070671 0.598844232132747 GO:0035251 UDP-glucosyltransferase activity 3/3194 12/18639 0.25 1.45890732623669 0.339284667070671 0.598844232132747 GO:0043047 single-stranded telomeric DNA binding 3/3194 12/18639 0.25 1.45890732623669 0.339284667070671 0.598844232132747 GO:0141221 histone deacetylase activity, hydrolytic mechanism 3/3194 12/18639 0.25 1.45890732623669 0.339284667070671 0.598844232132747 GO:1990459 transferrin receptor binding 3/3194 12/18639 0.25 1.45890732623669 0.339284667070671 0.598844232132747 GO:0045499 chemorepellent activity 6/3194 28/18639 0.214285714285714 1.25049199391717 0.34459422372753 0.60498481244063 GO:0050698 proteoglycan sulfotransferase activity 6/3194 28/18639 0.214285714285714 1.25049199391717 0.34459422372753 0.60498481244063 GO:0051119 sugar transmembrane transporter activity 6/3194 28/18639 0.214285714285714 1.25049199391717 0.34459422372753 0.60498481244063 GO:0051959 dynein light intermediate chain binding 6/3194 28/18639 0.214285714285714 1.25049199391717 0.34459422372753 0.60498481244063 GO:0003887 DNA-directed DNA polymerase activity 5/3194 23/18639 0.217391304347826 1.26861506629278 0.357952936293842 0.624677244089082 GO:0008171 O-methyltransferase activity 5/3194 23/18639 0.217391304347826 1.26861506629278 0.357952936293842 0.624677244089082 GO:0016493 C-C chemokine receptor activity 5/3194 23/18639 0.217391304347826 1.26861506629278 0.357952936293842 0.624677244089082 GO:0016849 phosphorus-oxygen lyase activity 5/3194 23/18639 0.217391304347826 1.26861506629278 0.357952936293842 0.624677244089082 GO:0008173 RNA methyltransferase activity 13/3194 67/18639 0.194029850746269 1.13228628304937 0.358646012302279 0.624677244089082 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 13/3194 67/18639 0.194029850746269 1.13228628304937 0.358646012302279 0.624677244089082 GO:0005200 structural constituent of cytoskeleton 21/3194 112/18639 0.1875 1.09418049467752 0.362068925855937 0.628958220438036 GO:0043022 ribosome binding 21/3194 112/18639 0.1875 1.09418049467752 0.362068925855937 0.628958220438036 GO:0008175 tRNA methyltransferase activity 7/3194 34/18639 0.205882352941176 1.20145309219492 0.362531137650366 0.628958220438036 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 4/3194 18/18639 0.222222222222222 1.29680651221039 0.372905007662739 0.642738487783755 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 4/3194 18/18639 0.222222222222222 1.29680651221039 0.372905007662739 0.642738487783755 GO:0015373 monoatomic anion:sodium symporter activity 4/3194 18/18639 0.222222222222222 1.29680651221039 0.372905007662739 0.642738487783755 GO:0035615 clathrin adaptor activity 4/3194 18/18639 0.222222222222222 1.29680651221039 0.372905007662739 0.642738487783755 GO:1901611 phosphatidylglycerol binding 4/3194 18/18639 0.222222222222222 1.29680651221039 0.372905007662739 0.642738487783755 GO:0016830 carbon-carbon lyase activity 10/3194 51/18639 0.196078431372549 1.14424104018564 0.374447236090324 0.64452676376206 GO:0015370 solute:sodium symporter activity 15/3194 79/18639 0.189873417721519 1.1080308806861 0.375405149846283 0.64452676376206 GO:0033293 monocarboxylic acid binding 15/3194 79/18639 0.189873417721519 1.1080308806861 0.375405149846283 0.64452676376206 GO:0050997 quaternary ammonium group binding 8/3194 40/18639 0.2 1.16712586098936 0.376970644338062 0.646375086660075 GO:0043236 laminin binding 6/3194 29/18639 0.206896551724138 1.20737158033382 0.377604370883171 0.646623028895792 GO:0015171 amino acid transmembrane transporter activity 19/3194 102/18639 0.186274509803922 1.08702898817636 0.383855059452498 0.656476569982151 GO:0003678 DNA helicase activity 14/3194 74/18639 0.189189189189189 1.10403797661155 0.388006661665354 0.65929738435033 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 3/3194 13/18639 0.230769230769231 1.34668368575695 0.389992855190589 0.65929738435033 GO:0005172 vascular endothelial growth factor receptor binding 3/3194 13/18639 0.230769230769231 1.34668368575695 0.389992855190589 0.65929738435033 GO:0017154 semaphorin receptor activity 3/3194 13/18639 0.230769230769231 1.34668368575695 0.389992855190589 0.65929738435033 GO:0019855 calcium channel inhibitor activity 3/3194 13/18639 0.230769230769231 1.34668368575695 0.389992855190589 0.65929738435033 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 3/3194 13/18639 0.230769230769231 1.34668368575695 0.389992855190589 0.65929738435033 GO:0046975 histone H3K36 methyltransferase activity 3/3194 13/18639 0.230769230769231 1.34668368575695 0.389992855190589 0.65929738435033 GO:0140666 annealing activity 3/3194 13/18639 0.230769230769231 1.34668368575695 0.389992855190589 0.65929738435033 GO:1901338 catecholamine binding 3/3194 13/18639 0.230769230769231 1.34668368575695 0.389992855190589 0.65929738435033 GO:0005507 copper ion binding 12/3194 63/18639 0.19047619047619 1.11154843903748 0.393525972007315 0.662278251852939 GO:0046943 carboxylic acid transmembrane transporter activity 34/3194 188/18639 0.180851063829787 1.05537976791591 0.393863168428406 0.662278251852939 GO:0030215 semaphorin receptor binding 5/3194 24/18639 0.208333333333333 1.21575610519724 0.394761923192221 0.662278251852939 GO:0030552 cAMP binding 5/3194 24/18639 0.208333333333333 1.21575610519724 0.394761923192221 0.662278251852939 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 5/3194 24/18639 0.208333333333333 1.21575610519724 0.394761923192221 0.662278251852939 GO:0070840 dynein complex binding 5/3194 24/18639 0.208333333333333 1.21575610519724 0.394761923192221 0.662278251852939 GO:0005080 protein kinase C binding 10/3194 52/18639 0.192307692307692 1.12223640479746 0.399235010188531 0.668933692609935 GO:0016877 ligase activity, forming carbon-sulfur bonds 8/3194 41/18639 0.195121951219512 1.13865937657498 0.405046634772797 0.677812216670427 GO:0005342 organic acid transmembrane transporter activity 34/3194 189/18639 0.17989417989418 1.04979574797984 0.406848609424136 0.679966955320743 GO:0017116 single-stranded DNA helicase activity 11/3194 58/18639 0.189655172413793 1.10675728197266 0.40814861237753 0.681278365609968 GO:0031210 phosphatidylcholine binding 6/3194 30/18639 0.2 1.16712586098936 0.410658714859516 0.683741588216978 GO:0033612 receptor serine/threonine kinase binding 6/3194 30/18639 0.2 1.16712586098936 0.410658714859516 0.683741588216978 GO:0008301 DNA binding, bending 4/3194 19/18639 0.210526315789474 1.22855353788353 0.414884297113124 0.687998781958023 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 4/3194 19/18639 0.210526315789474 1.22855353788353 0.414884297113124 0.687998781958023 GO:0043395 heparan sulfate proteoglycan binding 4/3194 19/18639 0.210526315789474 1.22855353788353 0.414884297113124 0.687998781958023 GO:0005504 fatty acid binding 9/3194 47/18639 0.191489361702128 1.11746093073449 0.415297298035176 0.687998781958023 GO:0004190 aspartic-type endopeptidase activity 7/3194 36/18639 0.194444444444444 1.1347056981841 0.423030027551212 0.699932035572844 GO:0005246 calcium channel regulator activity 10/3194 53/18639 0.188679245283019 1.10106213300883 0.424075973540767 0.700785546276118 GO:0046873 metal ion transmembrane transporter activity 79/3194 450/18639 0.175555555555556 1.02447714464621 0.425255259383259 0.701856994887227 GO:0003707 nuclear steroid receptor activity 5/3194 25/18639 0.2 1.16712586098936 0.431365657722077 0.709017876868332 GO:0047617 fatty acyl-CoA hydrolase activity 5/3194 25/18639 0.2 1.16712586098936 0.431365657722077 0.709017876868332 GO:0015459 potassium channel regulator activity 11/3194 59/18639 0.186440677966102 1.08799868397313 0.431739327442517 0.709017876868332 GO:0070888 E-box binding 11/3194 59/18639 0.186440677966102 1.08799868397313 0.431739327442517 0.709017876868332 GO:0004520 DNA endonuclease activity 8/3194 42/18639 0.19047619047619 1.11154843903748 0.433103088894659 0.709494775116157 GO:0019894 kinesin binding 8/3194 42/18639 0.19047619047619 1.11154843903748 0.433103088894659 0.709494775116157 GO:0004065 arylsulfatase activity 3/3194 14/18639 0.214285714285714 1.25049199391717 0.439653893461638 0.711410584034621 GO:0005313 L-glutamate transmembrane transporter activity 3/3194 14/18639 0.214285714285714 1.25049199391717 0.439653893461638 0.711410584034621 GO:0005347 ATP transmembrane transporter activity 3/3194 14/18639 0.214285714285714 1.25049199391717 0.439653893461638 0.711410584034621 GO:0008174 mRNA methyltransferase activity 3/3194 14/18639 0.214285714285714 1.25049199391717 0.439653893461638 0.711410584034621 GO:0019763 immunoglobulin receptor activity 3/3194 14/18639 0.214285714285714 1.25049199391717 0.439653893461638 0.711410584034621 GO:0034236 protein kinase A catalytic subunit binding 3/3194 14/18639 0.214285714285714 1.25049199391717 0.439653893461638 0.711410584034621 GO:0043176 amine binding 3/3194 14/18639 0.214285714285714 1.25049199391717 0.439653893461638 0.711410584034621 GO:0071933 Arp2/3 complex binding 3/3194 14/18639 0.214285714285714 1.25049199391717 0.439653893461638 0.711410584034621 GO:0098821 BMP receptor activity 3/3194 14/18639 0.214285714285714 1.25049199391717 0.439653893461638 0.711410584034621 GO:1990825 sequence-specific mRNA binding 3/3194 14/18639 0.214285714285714 1.25049199391717 0.439653893461638 0.711410584034621 GO:0016879 ligase activity, forming carbon-nitrogen bonds 9/3194 48/18639 0.1875 1.09418049467752 0.441574067368698 0.71364415288682 GO:0051287 NAD binding 10/3194 54/18639 0.185185185185185 1.08067209350866 0.448872041243497 0.724552916390603 GO:0001972 retinoic acid binding 4/3194 20/18639 0.2 1.16712586098936 0.456194273912832 0.733684708166379 GO:0016505 peptidase activator activity involved in apoptotic process 4/3194 20/18639 0.2 1.16712586098936 0.456194273912832 0.733684708166379 GO:0031418 L-ascorbic acid binding 4/3194 20/18639 0.2 1.16712586098936 0.456194273912832 0.733684708166379 GO:0015081 sodium ion transmembrane transporter activity 29/3194 164/18639 0.176829268292683 1.03191006002108 0.458244005843411 0.736085754222344 GO:0015085 calcium ion transmembrane transporter activity 26/3194 147/18639 0.17687074829932 1.03215212196338 0.46345333086903 0.743550125496186 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 5/3194 26/18639 0.192307692307692 1.12223640479746 0.467475997425616 0.745480420502611 GO:0015145 monosaccharide transmembrane transporter activity 5/3194 26/18639 0.192307692307692 1.12223640479746 0.467475997425616 0.745480420502611 GO:0016289 acyl-CoA hydrolase activity 5/3194 26/18639 0.192307692307692 1.12223640479746 0.467475997425616 0.745480420502611 GO:0050750 low-density lipoprotein particle receptor binding 5/3194 26/18639 0.192307692307692 1.12223640479746 0.467475997425616 0.745480420502611 GO:0097602 cullin family protein binding 5/3194 26/18639 0.192307692307692 1.12223640479746 0.467475997425616 0.745480420502611 GO:0016829 lyase activity 35/3194 200/18639 0.175 1.02123512836569 0.474801479365371 0.75453136487559 GO:0008378 galactosyltransferase activity 6/3194 32/18639 0.1875 1.09418049467752 0.4760054147551 0.75453136487559 GO:0015106 bicarbonate transmembrane transporter activity 6/3194 32/18639 0.1875 1.09418049467752 0.4760054147551 0.75453136487559 GO:0042910 xenobiotic transmembrane transporter activity 6/3194 32/18639 0.1875 1.09418049467752 0.4760054147551 0.75453136487559 GO:0043425 bHLH transcription factor binding 6/3194 32/18639 0.1875 1.09418049467752 0.4760054147551 0.75453136487559 GO:0019905 syntaxin binding 11/3194 61/18639 0.180327868852459 1.05232659597401 0.47868575431673 0.757871337972116 GO:0015399 primary active transmembrane transporter activity 29/3194 166/18639 0.174698795180723 1.01947740869552 0.486622537561981 0.76385495342113 GO:0004559 alpha-mannosidase activity 3/3194 15/18639 0.2 1.16712586098936 0.487665340913338 0.76385495342113 GO:0004953 icosanoid receptor activity 3/3194 15/18639 0.2 1.16712586098936 0.487665340913338 0.76385495342113 GO:0015556 C4-dicarboxylate transmembrane transporter activity 3/3194 15/18639 0.2 1.16712586098936 0.487665340913338 0.76385495342113 GO:0015929 hexosaminidase activity 3/3194 15/18639 0.2 1.16712586098936 0.487665340913338 0.76385495342113 GO:0031386 protein tag activity 3/3194 15/18639 0.2 1.16712586098936 0.487665340913338 0.76385495342113 GO:0048531 beta-1,3-galactosyltransferase activity 3/3194 15/18639 0.2 1.16712586098936 0.487665340913338 0.76385495342113 GO:0140776 protein-containing complex destabilizing activity 3/3194 15/18639 0.2 1.16712586098936 0.487665340913338 0.76385495342113 GO:0141047 molecular tag activity 3/3194 15/18639 0.2 1.16712586098936 0.487665340913338 0.76385495342113 GO:0016790 thiolester hydrolase activity 8/3194 44/18639 0.181818181818182 1.06102350999032 0.488618324019036 0.764441922311438 GO:0001846 opsonin binding 4/3194 21/18639 0.19047619047619 1.11154843903748 0.496467595727848 0.774888030167904 GO:0140312 cargo adaptor activity 4/3194 21/18639 0.19047619047619 1.11154843903748 0.496467595727848 0.774888030167904 GO:0170055 lipid transmembrane transporter activity 10/3194 56/18639 0.178571428571429 1.04207666159764 0.497960369048952 0.776301424389993 GO:0035255 ionotropic glutamate receptor binding 5/3194 27/18639 0.185185185185185 1.08067209350866 0.502840119445106 0.782985439230188 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 6/3194 33/18639 0.181818181818182 1.06102350999032 0.507901572956279 0.789936328762589 GO:0141110 transporter inhibitor activity 8/3194 45/18639 0.177777777777778 1.03744520976832 0.51583156319973 0.801327058225667 GO:0052689 carboxylic ester hydrolase activity 16/3194 92/18639 0.173913043478261 1.01489205303422 0.517244414146804 0.802578774063468 GO:0008194 UDP-glycosyltransferase activity 25/3194 145/18639 0.172413793103448 1.00614298361151 0.521098221350814 0.807072543577752 GO:0001094 TFIID-class transcription factor complex binding 2/3194 10/18639 0.2 1.16712586098936 0.531769444784905 0.807072543577752 GO:0004935 adrenergic receptor activity 2/3194 10/18639 0.2 1.16712586098936 0.531769444784905 0.807072543577752 GO:0005337 nucleoside transmembrane transporter activity 2/3194 10/18639 0.2 1.16712586098936 0.531769444784905 0.807072543577752 GO:0005345 purine nucleobase transmembrane transporter activity 2/3194 10/18639 0.2 1.16712586098936 0.531769444784905 0.807072543577752 GO:0005528 FK506 binding 2/3194 10/18639 0.2 1.16712586098936 0.531769444784905 0.807072543577752 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 2/3194 10/18639 0.2 1.16712586098936 0.531769444784905 0.807072543577752 GO:0015203 polyamine transmembrane transporter activity 2/3194 10/18639 0.2 1.16712586098936 0.531769444784905 0.807072543577752 GO:0016175 superoxide-generating NAD(P)H oxidase activity 2/3194 10/18639 0.2 1.16712586098936 0.531769444784905 0.807072543577752 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 2/3194 10/18639 0.2 1.16712586098936 0.531769444784905 0.807072543577752 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 2/3194 10/18639 0.2 1.16712586098936 0.531769444784905 0.807072543577752 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 2/3194 10/18639 0.2 1.16712586098936 0.531769444784905 0.807072543577752 GO:0035374 chondroitin sulfate binding 2/3194 10/18639 0.2 1.16712586098936 0.531769444784905 0.807072543577752 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 2/3194 10/18639 0.2 1.16712586098936 0.531769444784905 0.807072543577752 GO:0045322 unmethylated CpG binding 2/3194 10/18639 0.2 1.16712586098936 0.531769444784905 0.807072543577752 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 2/3194 10/18639 0.2 1.16712586098936 0.531769444784905 0.807072543577752 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 2/3194 10/18639 0.2 1.16712586098936 0.531769444784905 0.807072543577752 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 2/3194 10/18639 0.2 1.16712586098936 0.531769444784905 0.807072543577752 GO:0000062 fatty-acyl-CoA binding 3/3194 16/18639 0.1875 1.09418049467752 0.533571409294217 0.807072543577752 GO:0015562 efflux transmembrane transporter activity 3/3194 16/18639 0.1875 1.09418049467752 0.533571409294217 0.807072543577752 GO:0016722 oxidoreductase activity, acting on metal ions 3/3194 16/18639 0.1875 1.09418049467752 0.533571409294217 0.807072543577752 GO:0043023 ribosomal large subunit binding 3/3194 16/18639 0.1875 1.09418049467752 0.533571409294217 0.807072543577752 GO:0016831 carboxy-lyase activity 6/3194 34/18639 0.176470588235294 1.02981693616708 0.539052380521832 0.814431139485557 GO:0140662 ATP-dependent protein folding chaperone 7/3194 40/18639 0.175 1.02123512836569 0.540819199749304 0.816167787749521 GO:0042562 hormone binding 16/3194 94/18639 0.170212765957447 0.993298605097323 0.554619267749256 0.836039534737191 GO:0022853 active monoatomic ion transmembrane transporter activity 20/3194 118/18639 0.169491525423729 0.989089712702843 0.559812458838509 0.842906686314931 GO:0019838 growth factor binding 23/3194 136/18639 0.169117647058824 0.986907897160117 0.56343818838899 0.847400779351814 GO:0140359 ABC-type transporter activity 8/3194 47/18639 0.170212765957447 0.993298605097323 0.568636185495581 0.850194702851285 GO:0005343 organic acid:sodium symporter activity 6/3194 35/18639 0.171428571428571 1.00039359513373 0.569315969301445 0.850194702851285 GO:0004629 phospholipase C activity 5/3194 29/18639 0.172413793103448 1.00614298361151 0.570499115756104 0.850194702851285 GO:0035250 UDP-galactosyltransferase activity 5/3194 29/18639 0.172413793103448 1.00614298361151 0.570499115756104 0.850194702851285 GO:0099604 ligand-gated calcium channel activity 5/3194 29/18639 0.172413793103448 1.00614298361151 0.570499115756104 0.850194702851285 GO:0005283 amino acid:sodium symporter activity 4/3194 23/18639 0.173913043478261 1.01489205303422 0.572760491184191 0.850194702851285 GO:0005092 GDP-dissociation inhibitor activity 3/3194 17/18639 0.176470588235294 1.02981693616708 0.577045911469177 0.850194702851285 GO:0009881 photoreceptor activity 3/3194 17/18639 0.176470588235294 1.02981693616708 0.577045911469177 0.850194702851285 GO:0015278 intracellularly gated calcium channel activity 3/3194 17/18639 0.176470588235294 1.02981693616708 0.577045911469177 0.850194702851285 GO:0015347 sodium-independent organic anion transmembrane transporter activity 3/3194 17/18639 0.176470588235294 1.02981693616708 0.577045911469177 0.850194702851285 GO:0031489 myosin V binding 3/3194 17/18639 0.176470588235294 1.02981693616708 0.577045911469177 0.850194702851285 GO:1901567 fatty acid derivative binding 3/3194 17/18639 0.176470588235294 1.02981693616708 0.577045911469177 0.850194702851285 GO:0004866 endopeptidase inhibitor activity 27/3194 161/18639 0.167701863354037 0.978645908283 0.581999276970744 0.850194702851285 GO:0015078 proton transmembrane transporter activity 31/3194 185/18639 0.167567567567568 0.977862207855946 0.585302920199627 0.850194702851285 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 2/3194 11/18639 0.181818181818182 1.06102350999032 0.585875472237157 0.850194702851285 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 2/3194 11/18639 0.181818181818182 1.06102350999032 0.585875472237157 0.850194702851285 GO:0001851 complement component C3b binding 2/3194 11/18639 0.181818181818182 1.06102350999032 0.585875472237157 0.850194702851285 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 2/3194 11/18639 0.181818181818182 1.06102350999032 0.585875472237157 0.850194702851285 GO:0004143 ATP-dependent diacylglycerol kinase activity 2/3194 11/18639 0.181818181818182 1.06102350999032 0.585875472237157 0.850194702851285 GO:0008046 axon guidance receptor activity 2/3194 11/18639 0.181818181818182 1.06102350999032 0.585875472237157 0.850194702851285 GO:0010854 adenylate cyclase regulator activity 2/3194 11/18639 0.181818181818182 1.06102350999032 0.585875472237157 0.850194702851285 GO:0015205 nucleobase transmembrane transporter activity 2/3194 11/18639 0.181818181818182 1.06102350999032 0.585875472237157 0.850194702851285 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 2/3194 11/18639 0.181818181818182 1.06102350999032 0.585875472237157 0.850194702851285 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 2/3194 11/18639 0.181818181818182 1.06102350999032 0.585875472237157 0.850194702851285 GO:0019206 nucleoside kinase activity 2/3194 11/18639 0.181818181818182 1.06102350999032 0.585875472237157 0.850194702851285 GO:0019215 intermediate filament binding 2/3194 11/18639 0.181818181818182 1.06102350999032 0.585875472237157 0.850194702851285 GO:0019864 IgG binding 2/3194 11/18639 0.181818181818182 1.06102350999032 0.585875472237157 0.850194702851285 GO:0031731 CCR6 chemokine receptor binding 2/3194 11/18639 0.181818181818182 1.06102350999032 0.585875472237157 0.850194702851285 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 2/3194 11/18639 0.181818181818182 1.06102350999032 0.585875472237157 0.850194702851285 GO:0034511 U3 snoRNA binding 2/3194 11/18639 0.181818181818182 1.06102350999032 0.585875472237157 0.850194702851285 GO:0045294 alpha-catenin binding 2/3194 11/18639 0.181818181818182 1.06102350999032 0.585875472237157 0.850194702851285 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 2/3194 11/18639 0.181818181818182 1.06102350999032 0.585875472237157 0.850194702851285 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 10/3194 60/18639 0.166666666666667 0.972604884157796 0.59186345973962 0.857942427385722 GO:0004869 cysteine-type endopeptidase inhibitor activity 6/3194 36/18639 0.166666666666667 0.972604884157796 0.598573157651492 0.865769928244281 GO:0055106 ubiquitin-protein transferase regulator activity 6/3194 36/18639 0.166666666666667 0.972604884157796 0.598573157651492 0.865769928244281 GO:0004806 triacylglycerol lipase activity 4/3194 24/18639 0.166666666666667 0.972604884157796 0.608360204782585 0.876091711026773 GO:0015149 hexose transmembrane transporter activity 4/3194 24/18639 0.166666666666667 0.972604884157796 0.608360204782585 0.876091711026773 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 4/3194 24/18639 0.166666666666667 0.972604884157796 0.608360204782585 0.876091711026773 GO:0055056 D-glucose transmembrane transporter activity 4/3194 24/18639 0.166666666666667 0.972604884157796 0.608360204782585 0.876091711026773 GO:0030414 peptidase inhibitor activity 28/3194 169/18639 0.165680473372781 0.966849825671655 0.609861089464418 0.876994315712046 GO:0016835 carbon-oxygen lyase activity 13/3194 79/18639 0.164556962025316 0.96029342992795 0.610313744671015 0.876994315712046 GO:0000400 four-way junction DNA binding 3/3194 18/18639 0.166666666666667 0.972604884157796 0.617874092230464 0.879256781408691 GO:0003746 translation elongation factor activity 3/3194 18/18639 0.166666666666667 0.972604884157796 0.617874092230464 0.879256781408691 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 3/3194 18/18639 0.166666666666667 0.972604884157796 0.617874092230464 0.879256781408691 GO:0016854 racemase and epimerase activity 3/3194 18/18639 0.166666666666667 0.972604884157796 0.617874092230464 0.879256781408691 GO:0017075 syntaxin-1 binding 3/3194 18/18639 0.166666666666667 0.972604884157796 0.617874092230464 0.879256781408691 GO:0017128 phospholipid scramblase activity 3/3194 18/18639 0.166666666666667 0.972604884157796 0.617874092230464 0.879256781408691 GO:0034185 apolipoprotein binding 3/3194 18/18639 0.166666666666667 0.972604884157796 0.617874092230464 0.879256781408691 GO:0098641 cadherin binding involved in cell-cell adhesion 3/3194 18/18639 0.166666666666667 0.972604884157796 0.617874092230464 0.879256781408691 GO:0099602 neurotransmitter receptor regulator activity 3/3194 18/18639 0.166666666666667 0.972604884157796 0.617874092230464 0.879256781408691 GO:0030551 cyclic nucleotide binding 6/3194 37/18639 0.162162162162162 0.946318265667045 0.626726757752369 0.886722263129398 GO:0016209 antioxidant activity 14/3194 86/18639 0.162790697674419 0.949986165921568 0.628061711216129 0.886722263129398 GO:0008327 methyl-CpG binding 5/3194 31/18639 0.161290322580645 0.941230533055931 0.633032294483584 0.886722263129398 GO:0047499 calcium-independent phospholipase A2 activity 5/3194 31/18639 0.161290322580645 0.941230533055931 0.633032294483584 0.886722263129398 GO:0140223 general transcription initiation factor activity 11/3194 68/18639 0.161764705882353 0.943998858153155 0.633137581859787 0.886722263129398 GO:0005165 neurotrophin receptor binding 2/3194 12/18639 0.166666666666667 0.972604884157796 0.635193633270454 0.886722263129398 GO:0005247 voltage-gated chloride channel activity 2/3194 12/18639 0.166666666666667 0.972604884157796 0.635193633270454 0.886722263129398 GO:0005436 sodium:phosphate symporter activity 2/3194 12/18639 0.166666666666667 0.972604884157796 0.635193633270454 0.886722263129398 GO:0008179 adenylate cyclase binding 2/3194 12/18639 0.166666666666667 0.972604884157796 0.635193633270454 0.886722263129398 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 2/3194 12/18639 0.166666666666667 0.972604884157796 0.635193633270454 0.886722263129398 GO:0008504 monoamine transmembrane transporter activity 2/3194 12/18639 0.166666666666667 0.972604884157796 0.635193633270454 0.886722263129398 GO:0015166 polyol transmembrane transporter activity 2/3194 12/18639 0.166666666666667 0.972604884157796 0.635193633270454 0.886722263129398 GO:0016208 AMP binding 2/3194 12/18639 0.166666666666667 0.972604884157796 0.635193633270454 0.886722263129398 GO:0017166 vinculin binding 2/3194 12/18639 0.166666666666667 0.972604884157796 0.635193633270454 0.886722263129398 GO:0045295 gamma-catenin binding 2/3194 12/18639 0.166666666666667 0.972604884157796 0.635193633270454 0.886722263129398 GO:0070679 inositol 1,4,5 trisphosphate binding 2/3194 12/18639 0.166666666666667 0.972604884157796 0.635193633270454 0.886722263129398 GO:0140829 bicarbonate:monoatomic anion antiporter activity 2/3194 12/18639 0.166666666666667 0.972604884157796 0.635193633270454 0.886722263129398 GO:0140900 chloride:bicarbonate antiporter activity 2/3194 12/18639 0.166666666666667 0.972604884157796 0.635193633270454 0.886722263129398 GO:0015645 fatty acid ligase activity 4/3194 25/18639 0.16 0.933700688791484 0.64207345184173 0.893495898247123 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 4/3194 25/18639 0.16 0.933700688791484 0.64207345184173 0.893495898247123 GO:0120515 fatty acid-CoA ligase activity 4/3194 25/18639 0.16 0.933700688791484 0.64207345184173 0.893495898247123 GO:0004175 endopeptidase activity 67/3194 405/18639 0.165432098765432 0.965400403534405 0.646085988436682 0.898134255219025 GO:0016248 channel inhibitor activity 7/3194 44/18639 0.159090909090909 0.928395571241532 0.647397797682359 0.899012487958066 GO:0008237 metallopeptidase activity 30/3194 184/18639 0.16304347826087 0.951461299719583 0.648431891084517 0.899503630654493 GO:0016298 lipase activity 21/3194 130/18639 0.161538461538462 0.942678580029864 0.653058835300383 0.901398799785223 GO:0005501 retinoid binding 6/3194 38/18639 0.157894736842105 0.921415153412649 0.653700512090498 0.901398799785223 GO:0019840 isoprenoid binding 6/3194 38/18639 0.157894736842105 0.921415153412649 0.653700512090498 0.901398799785223 GO:0003756 protein disulfide isomerase activity 3/3194 19/18639 0.157894736842105 0.921415153412649 0.655934678814966 0.901398799785223 GO:0015245 fatty acid transmembrane transporter activity 3/3194 19/18639 0.157894736842105 0.921415153412649 0.655934678814966 0.901398799785223 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 3/3194 19/18639 0.157894736842105 0.921415153412649 0.655934678814966 0.901398799785223 GO:0030506 ankyrin binding 3/3194 19/18639 0.157894736842105 0.921415153412649 0.655934678814966 0.901398799785223 GO:0046527 glucosyltransferase activity 3/3194 19/18639 0.157894736842105 0.921415153412649 0.655934678814966 0.901398799785223 GO:0120227 acyl-CoA binding 3/3194 19/18639 0.157894736842105 0.921415153412649 0.655934678814966 0.901398799785223 GO:0047498 calcium-dependent phospholipase A2 activity 5/3194 32/18639 0.15625 0.911817078897934 0.662111346285156 0.908942055855634 GO:0004435 phosphatidylinositol phospholipase C activity 4/3194 26/18639 0.153846153846154 0.897789123837965 0.673818443553751 0.92140969853779 GO:0030507 spectrin binding 4/3194 26/18639 0.153846153846154 0.897789123837965 0.673818443553751 0.92140969853779 GO:0070006 metalloaminopeptidase activity 4/3194 26/18639 0.153846153846154 0.897789123837965 0.673818443553751 0.92140969853779 GO:0003823 antigen binding 28/3194 174/18639 0.160919540229885 0.939066784704079 0.673981224270835 0.92140969853779 GO:0004536 DNA nuclease activity 10/3194 64/18639 0.15625 0.911817078897934 0.676747769852865 0.923600548655713 GO:0005542 folic acid binding 2/3194 13/18639 0.153846153846154 0.897789123837965 0.679775592921338 0.923600548655713 GO:0008253 5'-nucleotidase activity 2/3194 13/18639 0.153846153846154 0.897789123837965 0.679775592921338 0.923600548655713 GO:0061459 L-arginine transmembrane transporter activity 2/3194 13/18639 0.153846153846154 0.897789123837965 0.679775592921338 0.923600548655713 GO:0070700 BMP receptor binding 2/3194 13/18639 0.153846153846154 0.897789123837965 0.679775592921338 0.923600548655713 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 2/3194 13/18639 0.153846153846154 0.897789123837965 0.679775592921338 0.923600548655713 GO:0005326 neurotransmitter transmembrane transporter activity 3/3194 20/18639 0.15 0.875344395742016 0.691182985562401 0.937173237859994 GO:0010851 cyclase regulator activity 3/3194 20/18639 0.15 0.875344395742016 0.691182985562401 0.937173237859994 GO:0004519 endonuclease activity 20/3194 127/18639 0.15748031496063 0.9189967409365 0.697040543667546 0.94414712984477 GO:0016405 CoA-ligase activity 4/3194 27/18639 0.148148148148148 0.86453767480693 0.703553804268297 0.949546528737941 GO:0004620 phospholipase activity 17/3194 109/18639 0.155963302752294 0.91014402003757 0.703881619442193 0.949546528737941 GO:0004177 aminopeptidase activity 6/3194 40/18639 0.15 0.875344395742016 0.703899847324646 0.949546528737941 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 6/3194 40/18639 0.15 0.875344395742016 0.703899847324646 0.949546528737941 GO:0019199 transmembrane receptor protein kinase activity 12/3194 78/18639 0.153846153846154 0.897789123837965 0.704908443432209 0.949937780038105 GO:0017046 peptide hormone binding 8/3194 53/18639 0.150943396226415 0.88084970640706 0.708664764364284 0.954027310070859 GO:0015103 inorganic anion transmembrane transporter activity 26/3194 165/18639 0.157575757575758 0.91955370865828 0.712418833494293 0.958105491230371 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 14/3194 91/18639 0.153846153846154 0.897789123837965 0.71335461232108 0.958389021837874 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 5/3194 34/18639 0.147058823529412 0.858180780139232 0.715613706719607 0.960212056800837 GO:0004222 metalloendopeptidase activity 17/3194 110/18639 0.154545454545455 0.901869983491774 0.718370754969275 0.960212056800837 GO:0008494 translation activator activity 2/3194 14/18639 0.142857142857143 0.833661329278111 0.719795876164622 0.960212056800837 GO:0008559 ABC-type xenobiotic transporter activity 2/3194 14/18639 0.142857142857143 0.833661329278111 0.719795876164622 0.960212056800837 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 2/3194 14/18639 0.142857142857143 0.833661329278111 0.719795876164622 0.960212056800837 GO:0042043 neurexin family protein binding 2/3194 14/18639 0.142857142857143 0.833661329278111 0.719795876164622 0.960212056800837 GO:1901612 cardiolipin binding 2/3194 14/18639 0.142857142857143 0.833661329278111 0.719795876164622 0.960212056800837 GO:0015174 basic amino acid transmembrane transporter activity 3/3194 21/18639 0.142857142857143 0.833661329278111 0.723635550534827 0.96242072213988 GO:0070182 DNA polymerase binding 3/3194 21/18639 0.142857142857143 0.833661329278111 0.723635550534827 0.96242072213988 GO:1904047 S-adenosyl-L-methionine binding 3/3194 21/18639 0.142857142857143 0.833661329278111 0.723635550534827 0.96242072213988 GO:0004521 RNA endonuclease activity 11/3194 73/18639 0.150684931506849 0.879341402115267 0.72701339140339 0.965898857170082 GO:0005506 iron ion binding 24/3194 154/18639 0.155844155844156 0.909448722848848 0.727711998291529 0.965898857170082 GO:0051393 alpha-actinin binding 4/3194 28/18639 0.142857142857143 0.833661329278111 0.731272538125874 0.969651249149854 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 9/3194 61/18639 0.147540983606557 0.860994487615098 0.739877937727523 0.978275588427789 GO:0004623 phospholipase A2 activity 5/3194 35/18639 0.142857142857143 0.833661329278111 0.739996662955967 0.978275588427789 GO:0034061 DNA polymerase activity 5/3194 35/18639 0.142857142857143 0.833661329278111 0.739996662955967 0.978275588427789 GO:0008509 monoatomic anion transmembrane transporter activity 23/3194 149/18639 0.154362416107383 0.90080183901863 0.741654500420371 0.979487761793936 GO:0008093 cytoskeletal anchor activity 3/3194 22/18639 0.136363636363636 0.795767632492742 0.753356533953312 0.988882499705592 GO:0004089 carbonate dehydratase activity 2/3194 15/18639 0.133333333333333 0.778083907326237 0.755508266203281 0.988882499705592 GO:0004865 protein serine/threonine phosphatase inhibitor activity 2/3194 15/18639 0.133333333333333 0.778083907326237 0.755508266203281 0.988882499705592 GO:0008252 nucleotidase activity 2/3194 15/18639 0.133333333333333 0.778083907326237 0.755508266203281 0.988882499705592 GO:0010181 FMN binding 2/3194 15/18639 0.133333333333333 0.778083907326237 0.755508266203281 0.988882499705592 GO:0033130 acetylcholine receptor binding 2/3194 15/18639 0.133333333333333 0.778083907326237 0.755508266203281 0.988882499705592 GO:0045504 dynein heavy chain binding 2/3194 15/18639 0.133333333333333 0.778083907326237 0.755508266203281 0.988882499705592 GO:0050780 dopamine receptor binding 2/3194 15/18639 0.133333333333333 0.778083907326237 0.755508266203281 0.988882499705592 GO:0140161 monocarboxylate:sodium symporter activity 2/3194 15/18639 0.133333333333333 0.778083907326237 0.755508266203281 0.988882499705592 GO:0004181 metallocarboxypeptidase activity 4/3194 29/18639 0.137931034482759 0.80491438688921 0.756996285705037 0.988882499705592 GO:0005416 amino acid:monoatomic cation symporter activity 4/3194 29/18639 0.137931034482759 0.80491438688921 0.756996285705037 0.988882499705592 GO:0045505 dynein intermediate chain binding 5/3194 36/18639 0.138888888888889 0.810504070131497 0.762806905747012 0.995489367618509 GO:0030170 pyridoxal phosphate binding 8/3194 56/18639 0.142857142857143 0.833661329278111 0.766233079304454 0.998974488008371 GO:0141108 transporter regulator activity 26/3194 170/18639 0.152941176470588 0.892508011344801 0.76806724847978 1 GO:0008200 ion channel inhibitor activity 6/3194 43/18639 0.13953488372093 0.814273856504201 0.76948430754485 1 GO:0048020 CCR chemokine receptor binding 7/3194 50/18639 0.14 0.816988102692549 0.776466511503394 1 GO:0017134 fibroblast growth factor binding 3/3194 23/18639 0.130434782608696 0.761169039775666 0.78044594036868 1 GO:0031681 G-protein beta-subunit binding 3/3194 23/18639 0.130434782608696 0.761169039775666 0.78044594036868 1 GO:0140103 catalytic activity, acting on a glycoprotein 3/3194 23/18639 0.130434782608696 0.761169039775666 0.78044594036868 1 GO:0001965 G-protein alpha-subunit binding 4/3194 30/18639 0.133333333333333 0.778083907326237 0.78076999182344 1 GO:0016769 transferase activity, transferring nitrogenous groups 4/3194 30/18639 0.133333333333333 0.778083907326237 0.78076999182344 1 GO:0008028 monocarboxylic acid transmembrane transporter activity 10/3194 70/18639 0.142857142857143 0.833661329278111 0.782267311126061 1 GO:0070279 vitamin B6 binding 8/3194 57/18639 0.140350877192982 0.819035691922354 0.783485262213276 1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 2/3194 16/18639 0.125 0.729453663118347 0.787213531476004 1 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/3194 16/18639 0.125 0.729453663118347 0.787213531476004 1 GO:0008296 3'-5'-DNA exonuclease activity 2/3194 16/18639 0.125 0.729453663118347 0.787213531476004 1 GO:0017070 U6 snRNA binding 2/3194 16/18639 0.125 0.729453663118347 0.787213531476004 1 GO:0016758 hexosyltransferase activity 30/3194 197/18639 0.152284263959391 0.888674513443671 0.788830986406484 1 GO:0099106 ion channel regulator activity 24/3194 160/18639 0.15 0.875344395742016 0.793412779183089 1 GO:0005010 insulin-like growth factor receptor activity 7/3194 51/18639 0.137254901960784 0.80096872812995 0.794120977449402 1 GO:0005030 neurotrophin receptor activity 7/3194 51/18639 0.137254901960784 0.80096872812995 0.794120977449402 1 GO:0005310 dicarboxylic acid transmembrane transporter activity 4/3194 31/18639 0.129032258064516 0.752984426444745 0.80265705809601 1 GO:0016878 acid-thiol ligase activity 4/3194 31/18639 0.129032258064516 0.752984426444745 0.80265705809601 1 GO:0016247 channel regulator activity 25/3194 168/18639 0.148809523809524 0.868397217998032 0.809857264622367 1 GO:0005518 collagen binding 10/3194 72/18639 0.138888888888889 0.810504070131497 0.81128308908197 1 GO:0042379 chemokine receptor binding 10/3194 72/18639 0.138888888888889 0.810504070131497 0.81128308908197 1 GO:0004550 nucleoside diphosphate kinase activity 2/3194 17/18639 0.117647058823529 0.686544624111385 0.815235880810247 1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 2/3194 17/18639 0.117647058823529 0.686544624111385 0.815235880810247 1 GO:0008569 minus-end-directed microtubule motor activity 2/3194 17/18639 0.117647058823529 0.686544624111385 0.815235880810247 1 GO:0016018 cyclosporin A binding 2/3194 17/18639 0.117647058823529 0.686544624111385 0.815235880810247 1 GO:0019198 transmembrane receptor protein phosphatase activity 2/3194 17/18639 0.117647058823529 0.686544624111385 0.815235880810247 1 GO:0030548 acetylcholine receptor regulator activity 2/3194 17/18639 0.117647058823529 0.686544624111385 0.815235880810247 1 GO:0032977 membrane insertase activity 2/3194 17/18639 0.117647058823529 0.686544624111385 0.815235880810247 1 GO:0045125 bioactive lipid receptor activity 2/3194 17/18639 0.117647058823529 0.686544624111385 0.815235880810247 1 GO:0048038 quinone binding 2/3194 17/18639 0.117647058823529 0.686544624111385 0.815235880810247 1 GO:0070492 oligosaccharide binding 2/3194 17/18639 0.117647058823529 0.686544624111385 0.815235880810247 1 GO:0008235 metalloexopeptidase activity 9/3194 66/18639 0.136363636363636 0.795767632492742 0.819838399244163 1 GO:0005262 calcium channel activity 19/3194 131/18639 0.145038167938931 0.846388983160219 0.819960490242373 1 GO:0004180 carboxypeptidase activity 6/3194 46/18639 0.130434782608696 0.761169039775666 0.823577080379184 1 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 6/3194 46/18639 0.130434782608696 0.761169039775666 0.823577080379184 1 GO:0005003 ephrin receptor activity 7/3194 53/18639 0.132075471698113 0.770743493106178 0.826225763207068 1 GO:0005005 transmembrane-ephrin receptor activity 7/3194 53/18639 0.132075471698113 0.770743493106178 0.826225763207068 1 GO:0008146 sulfotransferase activity 7/3194 53/18639 0.132075471698113 0.770743493106178 0.826225763207068 1 GO:0016860 intramolecular oxidoreductase activity 7/3194 53/18639 0.132075471698113 0.770743493106178 0.826225763207068 1 GO:0001848 complement binding 3/3194 25/18639 0.12 0.700275516593613 0.827250912113604 1 GO:0008483 transaminase activity 3/3194 25/18639 0.12 0.700275516593613 0.827250912113604 1 GO:0004714 transmembrane receptor protein tyrosine kinase activity 8/3194 60/18639 0.133333333333333 0.778083907326237 0.829569051678305 1 GO:0050840 extracellular matrix binding 9/3194 67/18639 0.134328358208955 0.783890503649567 0.833319376001862 1 GO:0008308 voltage-gated monoatomic anion channel activity 2/3194 18/18639 0.111111111111111 0.648403256105197 0.83990610438272 1 GO:0008409 5'-3' exonuclease activity 2/3194 18/18639 0.111111111111111 0.648403256105197 0.83990610438272 1 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 2/3194 18/18639 0.111111111111111 0.648403256105197 0.83990610438272 1 GO:0031690 adrenergic receptor binding 2/3194 18/18639 0.111111111111111 0.648403256105197 0.83990610438272 1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/3194 18/18639 0.111111111111111 0.648403256105197 0.83990610438272 1 GO:0016836 hydro-lyase activity 8/3194 61/18639 0.131147540983607 0.765328433435643 0.843107333029366 1 GO:0003777 microtubule motor activity 9/3194 68/18639 0.132352941176471 0.772362702125308 0.84600288524654 1 GO:0005227 calcium-activated cation channel activity 3/3194 26/18639 0.115384615384615 0.673341842878474 0.847263842795324 1 GO:0000182 rDNA binding 1/3194 10/18639 0.1 0.583562930494678 0.847441598060195 1 GO:0004090 carbonyl reductase (NADPH) activity 1/3194 10/18639 0.1 0.583562930494678 0.847441598060195 1 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/3194 10/18639 0.1 0.583562930494678 0.847441598060195 1 GO:0008190 eukaryotic initiation factor 4E binding 1/3194 10/18639 0.1 0.583562930494678 0.847441598060195 1 GO:0008401 retinoic acid 4-hydroxylase activity 1/3194 10/18639 0.1 0.583562930494678 0.847441598060195 1 GO:0008519 ammonium channel activity 1/3194 10/18639 0.1 0.583562930494678 0.847441598060195 1 GO:0015187 glycine transmembrane transporter activity 1/3194 10/18639 0.1 0.583562930494678 0.847441598060195 1 GO:0015279 store-operated calcium channel activity 1/3194 10/18639 0.1 0.583562930494678 0.847441598060195 1 GO:0016783 sulfurtransferase activity 1/3194 10/18639 0.1 0.583562930494678 0.847441598060195 1 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/3194 10/18639 0.1 0.583562930494678 0.847441598060195 1 GO:0031419 cobalamin binding 1/3194 10/18639 0.1 0.583562930494678 0.847441598060195 1 GO:0031956 medium-chain fatty acid-CoA ligase activity 1/3194 10/18639 0.1 0.583562930494678 0.847441598060195 1 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/3194 10/18639 0.1 0.583562930494678 0.847441598060195 1 GO:0032052 bile acid binding 1/3194 10/18639 0.1 0.583562930494678 0.847441598060195 1 GO:0032356 oxidized DNA binding 1/3194 10/18639 0.1 0.583562930494678 0.847441598060195 1 GO:0043121 neurotrophin binding 1/3194 10/18639 0.1 0.583562930494678 0.847441598060195 1 GO:0047429 nucleoside triphosphate diphosphatase activity 1/3194 10/18639 0.1 0.583562930494678 0.847441598060195 1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/3194 10/18639 0.1 0.583562930494678 0.847441598060195 1 GO:0070097 delta-catenin binding 1/3194 10/18639 0.1 0.583562930494678 0.847441598060195 1 GO:0070739 protein-glutamic acid ligase activity 1/3194 10/18639 0.1 0.583562930494678 0.847441598060195 1 GO:0070740 tubulin-glutamic acid ligase activity 1/3194 10/18639 0.1 0.583562930494678 0.847441598060195 1 GO:0140940 histone H2A methyltransferase activity 1/3194 10/18639 0.1 0.583562930494678 0.847441598060195 1 GO:1990259 histone H2AQ104 methyltransferase activity 1/3194 10/18639 0.1 0.583562930494678 0.847441598060195 1 GO:0004867 serine-type endopeptidase inhibitor activity 13/3194 95/18639 0.136842105263158 0.798559799624296 0.849674588816203 1 GO:0008238 exopeptidase activity 14/3194 102/18639 0.137254901960784 0.80096872812995 0.853771362144975 1 GO:0098632 cell-cell adhesion mediator activity 7/3194 55/18639 0.127272727272727 0.742716456993226 0.854253992583495 1 GO:0016853 isomerase activity 26/3194 180/18639 0.144444444444444 0.842924232936756 0.856806425072014 1 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 4/3194 34/18639 0.117647058823529 0.686544624111385 0.857822139565213 1 GO:0051427 hormone receptor binding 4/3194 34/18639 0.117647058823529 0.686544624111385 0.857822139565213 1 GO:0005229 intracellularly calcium-gated chloride channel activity 2/3194 19/18639 0.105263157894737 0.614276768941766 0.861549801508338 1 GO:0016918 retinal binding 2/3194 19/18639 0.105263157894737 0.614276768941766 0.861549801508338 1 GO:0022840 leak channel activity 2/3194 19/18639 0.105263157894737 0.614276768941766 0.861549801508338 1 GO:0022842 narrow pore channel activity 2/3194 19/18639 0.105263157894737 0.614276768941766 0.861549801508338 1 GO:0141147 intracellularly calcium-gated channel activity 2/3194 19/18639 0.105263157894737 0.614276768941766 0.861549801508338 1 GO:0005253 monoatomic anion channel activity 14/3194 103/18639 0.135922330097087 0.793192332711212 0.863324421620666 1 GO:0004364 glutathione transferase activity 3/3194 27/18639 0.111111111111111 0.648403256105197 0.865227597611202 1 GO:0005044 scavenger receptor activity 3/3194 27/18639 0.111111111111111 0.648403256105197 0.865227597611202 1 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 3/3194 27/18639 0.111111111111111 0.648403256105197 0.865227597611202 1 GO:0008083 growth factor activity 23/3194 162/18639 0.141975308641975 0.828515271689974 0.866008295292138 1 GO:0005004 GPI-linked ephrin receptor activity 6/3194 49/18639 0.122448979591837 0.714566853666952 0.867055408421182 1 GO:0005008 hepatocyte growth factor receptor activity 6/3194 49/18639 0.122448979591837 0.714566853666952 0.867055408421182 1 GO:0005009 insulin receptor activity 6/3194 49/18639 0.122448979591837 0.714566853666952 0.867055408421182 1 GO:0005011 macrophage colony-stimulating factor receptor activity 6/3194 49/18639 0.122448979591837 0.714566853666952 0.867055408421182 1 GO:0005018 platelet-derived growth factor alpha-receptor activity 6/3194 49/18639 0.122448979591837 0.714566853666952 0.867055408421182 1 GO:0005020 stem cell factor receptor activity 6/3194 49/18639 0.122448979591837 0.714566853666952 0.867055408421182 1 GO:0008288 boss receptor activity 6/3194 49/18639 0.122448979591837 0.714566853666952 0.867055408421182 1 GO:0036332 placental growth factor receptor activity 6/3194 49/18639 0.122448979591837 0.714566853666952 0.867055408421182 1 GO:0038062 protein tyrosine kinase collagen receptor activity 6/3194 49/18639 0.122448979591837 0.714566853666952 0.867055408421182 1 GO:0060175 brain-derived neurotrophic factor receptor activity 6/3194 49/18639 0.122448979591837 0.714566853666952 0.867055408421182 1 GO:0008307 structural constituent of muscle 5/3194 42/18639 0.119047619047619 0.694717774398426 0.868822325764583 1 GO:0042056 chemoattractant activity 5/3194 42/18639 0.119047619047619 0.694717774398426 0.868822325764583 1 GO:0004016 adenylate cyclase activity 1/3194 11/18639 0.0909090909090909 0.530511754995161 0.873598210642499 1 GO:0004523 RNA-DNA hybrid ribonuclease activity 1/3194 11/18639 0.0909090909090909 0.530511754995161 0.873598210642499 1 GO:0008172 S-methyltransferase activity 1/3194 11/18639 0.0909090909090909 0.530511754995161 0.873598210642499 1 GO:0008271 secondary active sulfate transmembrane transporter activity 1/3194 11/18639 0.0909090909090909 0.530511754995161 0.873598210642499 1 GO:0015217 ADP transmembrane transporter activity 1/3194 11/18639 0.0909090909090909 0.530511754995161 0.873598210642499 1 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 1/3194 11/18639 0.0909090909090909 0.530511754995161 0.873598210642499 1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/3194 11/18639 0.0909090909090909 0.530511754995161 0.873598210642499 1 GO:0035252 UDP-xylosyltransferase activity 1/3194 11/18639 0.0909090909090909 0.530511754995161 0.873598210642499 1 GO:0042285 xylosyltransferase activity 1/3194 11/18639 0.0909090909090909 0.530511754995161 0.873598210642499 1 GO:0050998 nitric-oxide synthase binding 1/3194 11/18639 0.0909090909090909 0.530511754995161 0.873598210642499 1 GO:0097493 structural molecule activity conferring elasticity 1/3194 11/18639 0.0909090909090909 0.530511754995161 0.873598210642499 1 GO:0005006 epidermal growth factor receptor activity 6/3194 50/18639 0.12 0.700275516593613 0.879408439819062 1 GO:0005007 fibroblast growth factor receptor activity 6/3194 50/18639 0.12 0.700275516593613 0.879408439819062 1 GO:0005017 platelet-derived growth factor receptor activity 6/3194 50/18639 0.12 0.700275516593613 0.879408439819062 1 GO:0005019 platelet-derived growth factor beta-receptor activity 6/3194 50/18639 0.12 0.700275516593613 0.879408439819062 1 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 2/3194 20/18639 0.1 0.583562930494678 0.880479447724554 1 GO:0016408 C-acyltransferase activity 2/3194 20/18639 0.1 0.583562930494678 0.880479447724554 1 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/3194 20/18639 0.1 0.583562930494678 0.880479447724554 1 GO:0051537 2 iron, 2 sulfur cluster binding 3/3194 28/18639 0.107142857142857 0.625245996958583 0.881302204749442 1 GO:0005245 voltage-gated calcium channel activity 5/3194 43/18639 0.116279069767442 0.678561547086834 0.8818931176356 1 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 5/3194 43/18639 0.116279069767442 0.678561547086834 0.8818931176356 1 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 4/3194 36/18639 0.111111111111111 0.648403256105197 0.886802742009959 1 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 4/3194 36/18639 0.111111111111111 0.648403256105197 0.886802742009959 1 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 4/3194 36/18639 0.111111111111111 0.648403256105197 0.886802742009959 1 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 4/3194 36/18639 0.111111111111111 0.648403256105197 0.886802742009959 1 GO:0005021 vascular endothelial growth factor receptor activity 6/3194 51/18639 0.117647058823529 0.686544624111385 0.89078010146835 1 GO:0030547 signaling receptor inhibitor activity 5/3194 44/18639 0.113636363636364 0.663139693743952 0.893833116705349 1 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/3194 12/18639 0.0833333333333333 0.486302442078898 0.895271354039957 1 GO:0003995 acyl-CoA dehydrogenase activity 1/3194 12/18639 0.0833333333333333 0.486302442078898 0.895271354039957 1 GO:0005049 nuclear export signal receptor activity 1/3194 12/18639 0.0833333333333333 0.486302442078898 0.895271354039957 1 GO:0008603 cAMP-dependent protein kinase regulator activity 1/3194 12/18639 0.0833333333333333 0.486302442078898 0.895271354039957 1 GO:0010853 cyclase activator activity 1/3194 12/18639 0.0833333333333333 0.486302442078898 0.895271354039957 1 GO:0016801 hydrolase activity, acting on ether bonds 1/3194 12/18639 0.0833333333333333 0.486302442078898 0.895271354039957 1 GO:0016803 ether hydrolase activity 1/3194 12/18639 0.0833333333333333 0.486302442078898 0.895271354039957 1 GO:0036009 protein-glutamine N-methyltransferase activity 1/3194 12/18639 0.0833333333333333 0.486302442078898 0.895271354039957 1 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/3194 12/18639 0.0833333333333333 0.486302442078898 0.895271354039957 1 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/3194 12/18639 0.0833333333333333 0.486302442078898 0.895271354039957 1 GO:0003785 actin monomer binding 3/3194 29/18639 0.103448275862069 0.603685790166908 0.895645195408412 1 GO:0009975 cyclase activity 2/3194 21/18639 0.0952380952380952 0.555774219518741 0.896989331639262 1 GO:0015125 bile acid transmembrane transporter activity 2/3194 21/18639 0.0952380952380952 0.555774219518741 0.896989331639262 1 GO:0000049 tRNA binding 10/3194 80/18639 0.125 0.729453663118347 0.898824470021286 1 GO:0022829 wide pore channel activity 4/3194 37/18639 0.108108108108108 0.63087884377803 0.89925526481466 1 GO:0015108 chloride transmembrane transporter activity 16/3194 121/18639 0.132231404958678 0.771653461811144 0.900835457282042 1 GO:0008009 chemokine activity 5/3194 45/18639 0.111111111111111 0.648403256105197 0.904714664876116 1 GO:0016500 protein-hormone receptor activity 8/3194 67/18639 0.119402985074627 0.696791558799615 0.90725476008603 1 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 3/3194 30/18639 0.1 0.583562930494678 0.908409106917853 1 GO:0022839 monoatomic ion-gated channel activity 3/3194 30/18639 0.1 0.583562930494678 0.908409106917853 1 GO:0048019 receptor antagonist activity 3/3194 30/18639 0.1 0.583562930494678 0.908409106917853 1 GO:0098918 structural constituent of synapse 3/3194 30/18639 0.1 0.583562930494678 0.908409106917853 1 GO:0005125 cytokine activity 33/3194 234/18639 0.141025641025641 0.822973363518135 0.910335543318472 1 GO:0000146 microfilament motor activity 4/3194 38/18639 0.105263157894737 0.614276768941766 0.91048267302226 1 GO:0038064 collagen receptor activity 6/3194 53/18639 0.113207547169811 0.660637279805295 0.910799915935787 1 GO:0008970 phospholipase A1 activity 2/3194 22/18639 0.0909090909090909 0.530511754995161 0.911352611407857 1 GO:0034062 5'-3' RNA polymerase activity 2/3194 22/18639 0.0909090909090909 0.530511754995161 0.911352611407857 1 GO:0097747 RNA polymerase activity 2/3194 22/18639 0.0909090909090909 0.530511754995161 0.911352611407857 1 GO:0004465 lipoprotein lipase activity 1/3194 13/18639 0.0769230769230769 0.448894561918983 0.913229334133176 1 GO:0004993 G protein-coupled serotonin receptor activity 1/3194 13/18639 0.0769230769230769 0.448894561918983 0.913229334133176 1 GO:0009982 pseudouridine synthase activity 1/3194 13/18639 0.0769230769230769 0.448894561918983 0.913229334133176 1 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/3194 13/18639 0.0769230769230769 0.448894561918983 0.913229334133176 1 GO:0019104 DNA N-glycosylase activity 1/3194 13/18639 0.0769230769230769 0.448894561918983 0.913229334133176 1 GO:0045159 myosin II binding 1/3194 13/18639 0.0769230769230769 0.448894561918983 0.913229334133176 1 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/3194 13/18639 0.0769230769230769 0.448894561918983 0.913229334133176 1 GO:0019842 vitamin binding 20/3194 150/18639 0.133333333333333 0.778083907326237 0.915073794087081 1 GO:0005539 glycosaminoglycan binding 34/3194 242/18639 0.140495867768595 0.81988180317434 0.917234743241373 1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 4/3194 39/18639 0.102564102564103 0.598526082558644 0.920581933952498 1 GO:0004602 glutathione peroxidase activity 2/3194 23/18639 0.0869565217391304 0.507446026517111 0.923819913411588 1 GO:0005212 structural constituent of eye lens 2/3194 23/18639 0.0869565217391304 0.507446026517111 0.923819913411588 1 GO:0099186 structural constituent of postsynapse 2/3194 23/18639 0.0869565217391304 0.507446026517111 0.923819913411588 1 GO:0008191 metalloendopeptidase inhibitor activity 1/3194 14/18639 0.0714285714285714 0.416830664639055 0.928108830899987 1 GO:0008331 high voltage-gated calcium channel activity 1/3194 14/18639 0.0714285714285714 0.416830664639055 0.928108830899987 1 GO:0008392 arachidonate epoxygenase activity 1/3194 14/18639 0.0714285714285714 0.416830664639055 0.928108830899987 1 GO:0015926 glucosidase activity 1/3194 14/18639 0.0714285714285714 0.416830664639055 0.928108830899987 1 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/3194 14/18639 0.0714285714285714 0.416830664639055 0.928108830899987 1 GO:0030983 mismatched DNA binding 1/3194 14/18639 0.0714285714285714 0.416830664639055 0.928108830899987 1 GO:0031404 chloride ion binding 1/3194 14/18639 0.0714285714285714 0.416830664639055 0.928108830899987 1 GO:0032036 myosin heavy chain binding 1/3194 14/18639 0.0714285714285714 0.416830664639055 0.928108830899987 1 GO:0061783 peptidoglycan muralytic activity 1/3194 14/18639 0.0714285714285714 0.416830664639055 0.928108830899987 1 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/3194 14/18639 0.0714285714285714 0.416830664639055 0.928108830899987 1 GO:0016782 transferase activity, transferring sulphur-containing groups 8/3194 70/18639 0.114285714285714 0.666929063422488 0.929917572123502 1 GO:0005540 hyaluronic acid binding 2/3194 24/18639 0.0833333333333333 0.486302442078898 0.934619031278007 1 GO:0140612 DNA damage sensor activity 2/3194 24/18639 0.0833333333333333 0.486302442078898 0.934619031278007 1 GO:0005523 tropomyosin binding 1/3194 15/18639 0.0666666666666667 0.389041953663118 0.940437442664038 1 GO:0008020 G protein-coupled photoreceptor activity 1/3194 15/18639 0.0666666666666667 0.389041953663118 0.940437442664038 1 GO:0015116 sulfate transmembrane transporter activity 1/3194 15/18639 0.0666666666666667 0.389041953663118 0.940437442664038 1 GO:0015250 water channel activity 1/3194 15/18639 0.0666666666666667 0.389041953663118 0.940437442664038 1 GO:0016846 carbon-sulfur lyase activity 1/3194 15/18639 0.0666666666666667 0.389041953663118 0.940437442664038 1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/3194 15/18639 0.0666666666666667 0.389041953663118 0.940437442664038 1 GO:0017081 chloride channel regulator activity 1/3194 15/18639 0.0666666666666667 0.389041953663118 0.940437442664038 1 GO:0030553 cGMP binding 1/3194 15/18639 0.0666666666666667 0.389041953663118 0.940437442664038 1 GO:0031005 filamin binding 1/3194 15/18639 0.0666666666666667 0.389041953663118 0.940437442664038 1 GO:0051371 muscle alpha-actinin binding 1/3194 15/18639 0.0666666666666667 0.389041953663118 0.940437442664038 1 GO:0004601 peroxidase activity 6/3194 57/18639 0.105263157894737 0.614276768941766 0.941470842071756 1 GO:1901681 sulfur compound binding 38/3194 275/18639 0.138181818181818 0.806377867592645 0.942840902533736 1 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 2/3194 25/18639 0.08 0.466850344395742 0.943955389466216 1 GO:0016859 cis-trans isomerase activity 4/3194 42/18639 0.0952380952380952 0.555774219518741 0.945022174173771 1 GO:0017171 serine hydrolase activity 26/3194 198/18639 0.131313131313131 0.766294757215233 0.948993761753409 1 GO:0016651 oxidoreductase activity, acting on NAD(P)H 10/3194 88/18639 0.113636363636364 0.663139693743952 0.949606489606658 1 GO:0003688 DNA replication origin binding 1/3194 16/18639 0.0625 0.364726831559173 0.950652370076573 1 GO:0008391 arachidonate monooxygenase activity 1/3194 16/18639 0.0625 0.364726831559173 0.950652370076573 1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/3194 16/18639 0.0625 0.364726831559173 0.950652370076573 1 GO:0022841 potassium ion leak channel activity 1/3194 16/18639 0.0625 0.364726831559173 0.950652370076573 1 GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity 1/3194 16/18639 0.0625 0.364726831559173 0.950652370076573 1 GO:0016597 amino acid binding 5/3194 51/18639 0.0980392156862745 0.572120520092821 0.951664003054991 1 GO:0004529 DNA exonuclease activity 2/3194 26/18639 0.0769230769230769 0.448894561918983 0.952013018355457 1 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 6/3194 59/18639 0.101694915254237 0.593453827621706 0.952947780152373 1 GO:0016229 steroid dehydrogenase activity 3/3194 35/18639 0.0857142857142857 0.500196797566866 0.953349203388169 1 GO:0016874 ligase activity 21/3194 167/18639 0.125748502994012 0.733821649125044 0.957474797036505 1 GO:0005104 fibroblast growth factor receptor binding 2/3194 27/18639 0.0740740740740741 0.432268837403465 0.958955852014997 1 GO:0015252 proton channel activity 2/3194 27/18639 0.0740740740740741 0.432268837403465 0.958955852014997 1 GO:0016805 dipeptidase activity 1/3194 17/18639 0.0588235294117647 0.343272312055693 0.959115900655719 1 GO:0045236 CXCR chemokine receptor binding 1/3194 17/18639 0.0588235294117647 0.343272312055693 0.959115900655719 1 GO:0005254 chloride channel activity 9/3194 83/18639 0.108433734939759 0.632779081259289 0.959438452894687 1 GO:0098631 cell adhesion mediator activity 8/3194 76/18639 0.105263157894737 0.614276768941766 0.96120331035131 1 GO:0051539 4 iron, 4 sulfur cluster binding 4/3194 45/18639 0.0888888888888889 0.518722604884158 0.962390031728931 1 GO:0001664 G protein-coupled receptor binding 40/3194 297/18639 0.134680134680135 0.785943340733573 0.964750700128813 1 GO:0005372 water transmembrane transporter activity 1/3194 18/18639 0.0555555555555556 0.324201628052599 0.966128241612954 1 GO:0015280 ligand-gated sodium channel activity 1/3194 18/18639 0.0555555555555556 0.324201628052599 0.966128241612954 1 GO:0022851 GABA-gated chloride ion channel activity 1/3194 18/18639 0.0555555555555556 0.324201628052599 0.966128241612954 1 GO:0070064 proline-rich region binding 1/3194 18/18639 0.0555555555555556 0.324201628052599 0.966128241612954 1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 4/3194 46/18639 0.0869565217391304 0.507446026517111 0.966940559297992 1 GO:0005109 frizzled binding 3/3194 38/18639 0.0789473684210526 0.460707576706324 0.969353356996992 1 GO:0008201 heparin binding 21/3194 172/18639 0.122093023255814 0.712489624441176 0.970310270659012 1 GO:0140299 molecular sensor activity 7/3194 71/18639 0.0985915492957746 0.575343734290527 0.970589739563757 1 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/3194 19/18639 0.0526315789473684 0.307138384470883 0.971938154952099 1 GO:0004890 GABA-A receptor activity 1/3194 19/18639 0.0526315789473684 0.307138384470883 0.971938154952099 1 GO:0008574 plus-end-directed microtubule motor activity 1/3194 19/18639 0.0526315789473684 0.307138384470883 0.971938154952099 1 GO:0070003 threonine-type peptidase activity 1/3194 19/18639 0.0526315789473684 0.307138384470883 0.971938154952099 1 GO:0099589 serotonin receptor activity 1/3194 19/18639 0.0526315789473684 0.307138384470883 0.971938154952099 1 GO:0008236 serine-type peptidase activity 24/3194 194/18639 0.123711340206186 0.721933522261457 0.973004928474367 1 GO:0015079 potassium ion transmembrane transporter activity 19/3194 160/18639 0.11875 0.69298097996243 0.974334855182984 1 GO:0019843 rRNA binding 6/3194 65/18639 0.0923076923076923 0.538673474302779 0.976209277853623 1 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/3194 20/18639 0.05 0.291781465247339 0.97675177112197 1 GO:0015464 acetylcholine receptor activity 1/3194 20/18639 0.05 0.291781465247339 0.97675177112197 1 GO:0140939 histone H4 methyltransferase activity 1/3194 20/18639 0.05 0.291781465247339 0.97675177112197 1 GO:0004252 serine-type endopeptidase activity 21/3194 176/18639 0.119318181818182 0.696296678431149 0.977977901509406 1 GO:0008227 G protein-coupled amine receptor activity 3/3194 41/18639 0.0731707317073171 0.426997266215618 0.980061527845269 1 GO:0017080 sodium channel regulator activity 3/3194 41/18639 0.0731707317073171 0.426997266215618 0.980061527845269 1 GO:0020037 heme binding 16/3194 142/18639 0.112676056338028 0.657535696332031 0.980371775584606 1 GO:0036122 BMP binding 1/3194 21/18639 0.0476190476190476 0.27788710975937 0.980739893096106 1 GO:0051428 peptide hormone receptor binding 1/3194 21/18639 0.0476190476190476 0.27788710975937 0.980739893096106 1 GO:0061891 calcium ion sensor activity 1/3194 21/18639 0.0476190476190476 0.27788710975937 0.980739893096106 1 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/3194 32/18639 0.0625 0.364726831559173 0.981470230843733 1 GO:0051536 iron-sulfur cluster binding 7/3194 76/18639 0.0921052631578947 0.537492172824045 0.983174516428581 1 GO:0005243 gap junction channel activity 1/3194 22/18639 0.0454545454545455 0.265255877497581 0.984044049366975 1 GO:0008649 rRNA methyltransferase activity 1/3194 22/18639 0.0454545454545455 0.265255877497581 0.984044049366975 1 GO:0030021 extracellular matrix structural constituent conferring compression resistance 1/3194 22/18639 0.0454545454545455 0.265255877497581 0.984044049366975 1 GO:0140784 metal ion sensor activity 1/3194 22/18639 0.0454545454545455 0.265255877497581 0.984044049366975 1 GO:0042923 neuropeptide binding 2/3194 33/18639 0.0606060606060606 0.353674503330108 0.984233281838027 1 GO:0046906 tetrapyrrole binding 17/3194 152/18639 0.111842105263158 0.652669067000626 0.984518551175501 1 GO:0051540 metal cluster binding 7/3194 77/18639 0.0909090909090909 0.530511754995161 0.984994423041973 1 GO:0019825 oxygen binding 2/3194 34/18639 0.0588235294117647 0.343272312055693 0.986593842686778 1 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/3194 23/18639 0.0434782608695652 0.253723013258555 0.986781510092219 1 GO:0016917 GABA receptor activity 1/3194 23/18639 0.0434782608695652 0.253723013258555 0.986781510092219 1 GO:0140102 catalytic activity, acting on a rRNA 1/3194 23/18639 0.0434782608695652 0.253723013258555 0.986781510092219 1 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 14/3194 132/18639 0.106060606060606 0.618930380827688 0.986936864747262 1 GO:0003954 NADH dehydrogenase activity 3/3194 44/18639 0.0681818181818182 0.397883816246371 0.987138284829687 1 GO:0004033 aldo-keto reductase (NADPH) activity 2/3194 36/18639 0.0555555555555556 0.324201628052599 0.990326892111858 1 GO:0000030 mannosyltransferase activity 1/3194 25/18639 0.04 0.233425172197871 0.990928362890686 1 GO:0005251 delayed rectifier potassium channel activity 1/3194 25/18639 0.04 0.233425172197871 0.990928362890686 1 GO:0015271 outward rectifier potassium channel activity 1/3194 25/18639 0.04 0.233425172197871 0.990928362890686 1 GO:0004497 monooxygenase activity 10/3194 106/18639 0.0943396226415094 0.550531066504413 0.991571755358433 1 GO:0099095 ligand-gated monoatomic anion channel activity 3/3194 47/18639 0.0638297872340425 0.372486976911496 0.991765658889249 1 GO:0030280 structural constituent of skin epidermis 2/3194 37/18639 0.0540540540540541 0.315439421889015 0.991790961865676 1 GO:0008188 neuropeptide receptor activity 3/3194 48/18639 0.0625 0.364726831559173 0.992913902452314 1 GO:0009055 electron transfer activity 11/3194 116/18639 0.0948275862068965 0.553378640986332 0.993304618869109 1 GO:0005242 inward rectifier potassium channel activity 1/3194 28/18639 0.0357142857142857 0.208415332319528 0.994842904644961 1 GO:0016866 intramolecular transferase activity 1/3194 28/18639 0.0357142857142857 0.208415332319528 0.994842904644961 1 GO:0008137 NADH dehydrogenase (ubiquinone) activity 2/3194 41/18639 0.0487804878048781 0.284664844143745 0.99576573787955 1 GO:0003730 mRNA 3'-UTR binding 30/3194 262/18639 0.114503816793893 0.668201828810699 0.996076857757767 1 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 3/3194 52/18639 0.0576923076923077 0.336670921439237 0.996140740530154 1 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/3194 30/18639 0.0333333333333333 0.194520976831559 0.996461162233534 1 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 11/3194 122/18639 0.0901639344262295 0.526163297987004 0.996475020003547 1 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 5/3194 73/18639 0.0684931506849315 0.399700637325122 0.997109386617059 1 GO:0015020 glucuronosyltransferase activity 1/3194 34/18639 0.0294117647058824 0.171636156027846 0.9983338518764 1 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 4/3194 68/18639 0.0588235294117647 0.343272312055693 0.998460138042238 1 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 3/3194 58/18639 0.0517241379310345 0.301842895083454 0.998477137346047 1 GO:0140101 catalytic activity, acting on a tRNA 12/3194 139/18639 0.0863309352517986 0.503795335678858 0.998683700368023 1 GO:0005272 sodium channel activity 2/3194 51/18639 0.0392156862745098 0.228848208037128 0.999216174188349 1 GO:0099094 ligand-gated monoatomic cation channel activity 11/3194 136/18639 0.0808823529411765 0.471999429076577 0.999275119468983 1 GO:0001653 peptide receptor activity 10/3194 128/18639 0.078125 0.455908539448967 0.999310367879572 1 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 2/3194 53/18639 0.0377358490566038 0.220212426601765 0.999443080618476 1 GO:0008528 G protein-coupled peptide receptor activity 9/3194 122/18639 0.0737704918032787 0.430497243807549 0.999498479274879 1 GO:0005267 potassium channel activity 9/3194 124/18639 0.0725806451612903 0.423553739875169 0.99960981309349 1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 2/3194 56/18639 0.0357142857142857 0.208415332319528 0.999667224256774 1 GO:0005249 voltage-gated potassium channel activity 6/3194 98/18639 0.0612244897959184 0.357283426833476 0.999670449608028 1 GO:0022843 voltage-gated monoatomic cation channel activity 11/3194 143/18639 0.0769230769230769 0.448894561918983 0.999683942061924 1 GO:0030020 extracellular matrix structural constituent conferring tensile strength 1/3194 44/18639 0.0227272727272727 0.13262793874879 0.999746774591167 1 GO:0022832 voltage-gated channel activity 14/3194 175/18639 0.08 0.466850344395742 0.999856100128706 1 GO:0022824 transmitter-gated monoatomic ion channel activity 2/3194 63/18639 0.0317460317460317 0.185258073172913 0.999900869369152 1 GO:0022835 transmitter-gated channel activity 2/3194 63/18639 0.0317460317460317 0.185258073172913 0.999900869369152 1 GO:0005244 voltage-gated monoatomic ion channel activity 13/3194 173/18639 0.0751445086705202 0.438515496903515 0.99993293403868 1 GO:0015276 ligand-gated monoatomic ion channel activity 14/3194 186/18639 0.0752688172043011 0.439240915426101 0.999960564796677 1 GO:0098960 postsynaptic neurotransmitter receptor activity 2/3194 69/18639 0.0289855072463768 0.169148675505704 0.999965208331227 1 GO:0022834 ligand-gated channel activity 14/3194 188/18639 0.074468085106383 0.434568139730079 0.999968990845838 1 GO:0005261 monoatomic cation channel activity 33/3194 341/18639 0.0967741935483871 0.564738319833559 0.99997092788722 1 GO:0005216 monoatomic ion channel activity 47/3194 448/18639 0.104910714285714 0.612220038688613 0.9999762914273 1 GO:0030594 neurotransmitter receptor activity 3/3194 97/18639 0.0309278350515464 0.180483380565364 0.999997449178535 1 GO:0005179 hormone activity 6/3194 132/18639 0.0454545454545455 0.265255877497581 0.999997744330709 1 GO:0005201 extracellular matrix structural constituent 9/3194 168/18639 0.0535714285714286 0.312622998479292 0.999998973038932 1 GO:0022836 gated channel activity 25/3194 318/18639 0.0786163522012579 0.458775888753677 0.999999579797627 1 GO:0030527 structural constituent of chromatin 1/3194 98/18639 0.0102040816326531 0.0595472378055793 0.999999990519982 1 GO:0003735 structural constituent of ribosome 3/3194 175/18639 0.0171428571428571 0.100039359513373 0.999999999996929 1 GO:0045182 translation regulator activity 13/3194 356/18639 0.0365168539325843 0.21309882293345 1 1 GO:0030371 translation repressor activity 9/3194 329/18639 0.027355623100304 0.159637275819213 1 1