ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0023023 MHC protein complex binding 22/1567 37/18639 0.594594594594595 7.07252625950775 5.20501440421218e-15 6.25122229945883e-12 GO:0023026 MHC class II protein complex binding 18/1567 27/18639 0.666666666666667 7.92980216975112 9.01418926044415e-14 4.25489663851731e-11 GO:0042605 peptide antigen binding 23/1567 45/18639 0.511111111111111 6.07951499680919 1.0628384609119e-13 4.25489663851731e-11 GO:0042277 peptide binding 55/1567 249/18639 0.220883534136546 2.62734409238742 2.13147716709318e-11 6.39976019419729e-09 GO:0140375 immune receptor activity 40/1567 156/18639 0.256410256410256 3.04992391144274 1.03154760687616e-10 2.47777735171654e-08 GO:0003779 actin binding 77/1567 443/18639 0.173814898419865 2.06747663793737 6.25677145473216e-10 1.25239708618889e-07 GO:0005126 cytokine receptor binding 55/1567 275/18639 0.2 2.37894065092534 1.10521949375334e-09 1.89624087428251e-07 GO:0032395 MHC class II receptor activity 8/1567 10/18639 0.8 9.51576260370134 9.46590496126564e-08 1.42106898231e-05 GO:0005539 glycosaminoglycan binding 46/1567 242/18639 0.190082644628099 2.2609766517059 1.23867538003465e-07 1.65294347935736e-05 GO:0045296 cadherin binding 57/1567 334/18639 0.170658682634731 2.02993438776563 1.99510775931081e-07 2.39612441893229e-05 GO:0005518 collagen binding 21/1567 72/18639 0.291666666666667 3.46928844926611 2.69206406336005e-07 2.93924449099584e-05 GO:0001968 fibronectin binding 13/1567 30/18639 0.433333333333333 5.15437141033823 3.05847969697884e-07 3.06102843005965e-05 GO:0005178 integrin binding 34/1567 161/18639 0.211180124223602 2.51192491091495 4.31759682523688e-07 3.98879522085346e-05 GO:0140272 exogenous protein binding 22/1567 82/18639 0.268292682926829 3.19126184880228 6.97028202234223e-07 5.85898774133054e-05 GO:0044389 ubiquitin-like protein ligase binding 54/1567 322/18639 0.167701863354037 1.99476389984423 7.31763664612473e-07 5.85898774133054e-05 GO:0031625 ubiquitin protein ligase binding 51/1567 302/18639 0.16887417218543 2.00870816551642 1.19300038000519e-06 8.95495910241398e-05 GO:0001618 virus receptor activity 21/1567 81/18639 0.259259259259259 3.08381195490321 2.27560396377304e-06 0.000160764727087731 GO:0019955 cytokine binding 30/1567 144/18639 0.208333333333333 2.47806317804722 2.71554978547539e-06 0.000181187516241997 GO:0033218 amide binding 43/1567 247/18639 0.174089068825911 2.07073781355849 3.60199267924016e-06 0.000227683853040391 GO:0004713 protein tyrosine kinase activity 29/1567 140/18639 0.207142857142857 2.46390281702981 4.46108115017542e-06 0.000265482346738094 GO:0005161 platelet-derived growth factor receptor binding 8/1567 14/18639 0.571428571428571 6.7969732883581 4.64207267402162e-06 0.000265482346738094 GO:1901681 sulfur compound binding 46/1567 275/18639 0.167272727272727 1.98965945350119 5.0909006495682e-06 0.000271510028413668 GO:0043394 proteoglycan binding 13/1567 37/18639 0.351351351351351 4.1792200624364 5.19960920359231e-06 0.000271510028413668 GO:0008201 heparin binding 33/1567 172/18639 0.191860465116279 2.28212329885279 5.85328846803481e-06 0.000292908310421242 GO:0019838 growth factor binding 28/1567 136/18639 0.205882352941176 2.44890949359961 7.32229998743954e-06 0.000351763291396596 GO:0042562 hormone binding 22/1567 94/18639 0.234042553191489 2.78386671916795 8.11609066558912e-06 0.000374900957283559 GO:0005520 insulin-like growth factor binding 9/1567 19/18639 0.473684210526316 5.63433312061264 8.7030864542162e-06 0.00038712617894495 GO:0003725 double-stranded RNA binding 19/1567 75/18639 0.253333333333333 3.01332482450542 9.83477752269698e-06 0.000421841707312824 GO:0031072 heat shock protein binding 27/1567 131/18639 0.206106870229008 2.4515800601139 1.03698583993677e-05 0.00042945517026347 GO:0004896 cytokine receptor activity 22/1567 96/18639 0.229166666666667 2.72586949585195 1.16366789226443e-05 0.000465855046203193 GO:0035259 nuclear glucocorticoid receptor binding 7/1567 12/18639 0.583333333333333 6.93857689853223 1.58898047481715e-05 0.000615601790404965 GO:0002020 protease binding 27/1567 136/18639 0.198529411764706 2.36144844025677 2.1182831142134e-05 0.000795018131303217 GO:0008083 growth factor activity 30/1567 162/18639 0.185185185185185 2.20272282493087 3.10204711003264e-05 0.00112757481117037 GO:0031994 insulin-like growth factor I binding 7/1567 13/18639 0.538461538461538 6.40484021402975 3.19213518566132e-05 0.00112757481117037 GO:0071813 lipoprotein particle binding 11/1567 32/18639 0.34375 4.08880424377792 3.51246209477436e-05 0.00117179638217334 GO:0071814 protein-lipid complex binding 11/1567 32/18639 0.34375 4.08880424377792 3.51246209477436e-05 0.00117179638217334 GO:0044183 protein folding chaperone 18/1567 75/18639 0.24 2.8547287811104 3.68632057751918e-05 0.00119655973340555 GO:0051087 protein-folding chaperone binding 26/1567 134/18639 0.194029850746269 2.30792749716637 4.51095485775827e-05 0.00141024445652486 GO:0001540 amyloid-beta binding 19/1567 83/18639 0.228915662650602 2.72288387756514 4.57947825182927e-05 0.00141024445652486 GO:0051019 mitogen-activated protein kinase binding 10/1567 28/18639 0.357142857142857 4.24810830522381 5.48309132977499e-05 0.00164629817176494 GO:0051082 unfolded protein binding 24/1567 121/18639 0.198347107438017 2.35927998438876 6.04830591649539e-05 0.00173287228465553 GO:0019903 protein phosphatase binding 27/1567 144/18639 0.1875 2.2302568602425 6.06000299379954e-05 0.00173287228465553 GO:0005125 cytokine activity 38/1567 234/18639 0.162393162393162 1.93161847724707 6.33287883524147e-05 0.00176878778630814 GO:0015291 secondary active transmembrane transporter activity 44/1567 287/18639 0.153310104529617 1.82357819931559 7.18233411599166e-05 0.00192361641999335 GO:0140662 ATP-dependent protein folding chaperone 12/1567 40/18639 0.3 3.568410976388 7.20755527890931e-05 0.00192361641999335 GO:0005525 GTP binding 54/1567 378/18639 0.142857142857143 1.69924332208953 8.2735418204339e-05 0.00211922332693961 GO:0030246 carbohydrate binding 43/1567 280/18639 0.153571428571429 1.82668657124624 8.29338021366877e-05 0.00211922332693961 GO:0070851 growth factor receptor binding 26/1567 139/18639 0.18705035971223 2.22490852244816 8.57863601437424e-05 0.00214644621942989 GO:0050840 extracellular matrix binding 16/1567 67/18639 0.238805970149254 2.84052615035861 0.000104775981672128 0.00256808069363726 GO:0005516 calmodulin binding 34/1567 207/18639 0.164251207729469 1.95371937515607 0.000119878071756199 0.00287947128358389 GO:0003924 GTPase activity 48/1567 331/18639 0.145015105740181 1.72491165021777 0.000139654615742139 0.00328872928443743 GO:0061135 endopeptidase regulator activity 31/1567 184/18639 0.168478260869565 2.00399891789906 0.000146380912349647 0.00332402906771046 GO:0070325 lipoprotein particle receptor binding 10/1567 31/18639 0.32258064516129 3.83700104987957 0.00014668904295475 0.00332402906771046 GO:0005201 extracellular matrix structural constituent 29/1567 168/18639 0.172619047619048 2.05325234752484 0.000153319592197875 0.00340994130054903 GO:0019001 guanyl nucleotide binding 55/1567 400/18639 0.1375 1.63552169751117 0.000196808545865214 0.00422084042114503 GO:0032561 guanyl ribonucleotide binding 55/1567 400/18639 0.1375 1.63552169751117 0.000196808545865214 0.00422084042114503 GO:0043531 ADP binding 11/1567 38/18639 0.289473684210526 3.44320357370772 0.000204570010587897 0.00431032601256254 GO:0019902 phosphatase binding 31/1567 190/18639 0.163157894736842 1.94071474154435 0.00026441512023516 0.00547521654142116 GO:0003823 antigen binding 29/1567 174/18639 0.166666666666667 1.98245054243778 0.00028484928212468 0.00579837267511424 GO:0061134 peptidase regulator activity 35/1567 226/18639 0.154867256637168 1.84210006155723 0.000309978021348721 0.00620472672733023 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 10/1567 34/18639 0.294117647058824 3.49844213371373 0.000343506600055918 0.00676313814208454 GO:0004866 endopeptidase inhibitor activity 27/1567 161/18639 0.167701863354037 1.99476389984423 0.000410393375844327 0.00794971684498446 GO:0042287 MHC protein binding 11/1567 41/18639 0.268292682926829 3.19126184880228 0.000424797184084533 0.00809811774738927 GO:0003714 transcription corepressor activity 32/1567 204/18639 0.156862745098039 1.86583580464732 0.000436718950870168 0.008195304062423 GO:0043177 organic acid binding 30/1567 189/18639 0.158730158730159 1.88804813565503 0.000530659282032962 0.00977128819072871 GO:0001221 transcription coregulator binding 21/1567 115/18639 0.182608695652174 2.17207624649705 0.00055324529306374 0.00977128819072871 GO:0035401 histone H3Y41 kinase activity 21/1567 115/18639 0.182608695652174 2.17207624649705 0.00055324529306374 0.00977128819072871 GO:0140801 histone H2AXY142 kinase activity 21/1567 115/18639 0.182608695652174 2.17207624649705 0.00055324529306374 0.00977128819072871 GO:0019207 kinase regulator activity 41/1567 287/18639 0.142857142857143 1.69924332208953 0.000563586459767125 0.00980967156783069 GO:0019209 kinase activator activity 25/1567 148/18639 0.168918918918919 2.00924041463288 0.000591061604242548 0.0101409283813614 GO:0022804 active transmembrane transporter activity 59/1567 457/18639 0.12910284463895 1.53564002630848 0.000619209126062725 0.0104742276112864 GO:0042288 MHC class I protein binding 7/1567 20/18639 0.35 4.16314613911934 0.000852024727163737 0.0140376820070908 GO:0038024 cargo receptor activity 14/1567 65/18639 0.215384615384615 2.5619360856119 0.000853247948807348 0.0140376820070908 GO:0030414 peptidase inhibitor activity 27/1567 169/18639 0.159763313609467 1.90033720636047 0.000888056600439403 0.0144129186098341 GO:0004857 enzyme inhibitor activity 54/1567 416/18639 0.129807692307692 1.54402398016789 0.000907959899268978 0.0145394645202939 GO:0031406 carboxylic acid binding 29/1567 187/18639 0.155080213903743 1.84463312504906 0.000952312410243085 0.0150490421671308 GO:0004879 nuclear receptor activity 13/1567 59/18639 0.220338983050847 2.62086681881605 0.00103240018781131 0.016102761370927 GO:0141003 histone H2AX kinase activity 47/1567 354/18639 0.132768361581921 1.57924026261993 0.00118127984027056 0.0181886806174992 GO:0098531 ligand-modulated transcription factor activity 13/1567 60/18639 0.216666666666667 2.57718570516911 0.0012181857469596 0.0183087935875389 GO:0019956 chemokine binding 9/1567 33/18639 0.272727272727273 3.24400997853455 0.00123481455502969 0.0183087935875389 GO:0071889 14-3-3 protein binding 9/1567 33/18639 0.272727272727273 3.24400997853455 0.00123481455502969 0.0183087935875389 GO:0003953 NAD+ nucleosidase activity 5/1567 11/18639 0.454545454545455 5.40668329755758 0.00125223783362604 0.0183407029046935 GO:0005159 insulin-like growth factor receptor binding 6/1567 16/18639 0.375 4.460513720485 0.00133791563129715 0.0189039608610338 GO:0022858 alanine transmembrane transporter activity 6/1567 16/18639 0.375 4.460513720485 0.00133791563129715 0.0189039608610338 GO:0055102 lipase inhibitor activity 6/1567 16/18639 0.375 4.460513720485 0.00133791563129715 0.0189039608610338 GO:0051015 actin filament binding 31/1567 209/18639 0.148325358851675 1.76428612867668 0.00136974530670886 0.0191286524808993 GO:0140996 histone H3 kinase activity 47/1567 357/18639 0.131652661064426 1.56596933604329 0.00140947854239016 0.0194572842460987 GO:0035173 histone kinase activity 47/1567 360/18639 0.130555555555556 1.55291959157626 0.00167550608040664 0.022866850029186 GO:0140828 metal cation:monoatomic cation antiporter activity 10/1567 41/18639 0.24390243902439 2.9011471352748 0.0017089316246081 0.0230609761927453 GO:0140313 molecular sequestering activity 12/1567 55/18639 0.218181818181818 2.59520798282764 0.00174144004830363 0.0232385499779184 GO:0030169 low-density lipoprotein particle binding 6/1567 17/18639 0.352941176470588 4.19813056045647 0.00192169522429402 0.0250864778736643 GO:0036041 long-chain fatty acid binding 6/1567 17/18639 0.352941176470588 4.19813056045647 0.00192169522429402 0.0250864778736643 GO:0004000 adenosine deaminase activity 5/1567 12/18639 0.416666666666667 4.95612635609445 0.00199870056131406 0.0258111760660019 GO:0001222 transcription corepressor binding 11/1567 49/18639 0.224489795918367 2.67023950614068 0.00210136921655098 0.0268483449901886 GO:0042379 chemokine receptor binding 14/1567 72/18639 0.194444444444444 2.31285896617741 0.00240469445294984 0.0304004003999238 GO:0032813 tumor necrosis factor receptor superfamily binding 11/1567 50/18639 0.22 2.61683471601787 0.00249302384123029 0.0308672333331709 GO:0048020 CCR chemokine receptor binding 11/1567 50/18639 0.22 2.61683471601787 0.00249302384123029 0.0308672333331709 GO:0051721 protein phosphatase 2A binding 8/1567 30/18639 0.266666666666667 3.17192086790045 0.00267542474012144 0.0325045286702555 GO:0032393 MHC class I receptor activity 6/1567 18/18639 0.333333333333333 3.96490108487556 0.00267939078963804 0.0325045286702555 GO:0060229 lipase activator activity 7/1567 24/18639 0.291666666666667 3.46928844926611 0.0028230752534954 0.0339051337944798 GO:0030295 protein kinase activator activity 22/1567 139/18639 0.158273381294964 1.88261490360998 0.00286501730113303 0.0340681760263442 GO:0042805 actinin binding 9/1567 37/18639 0.243243243243243 2.89330619707135 0.00293472774568484 0.0345549806134068 GO:0106310 protein serine kinase activity 46/1567 361/18639 0.127423822714681 1.51566855876129 0.00301026591018871 0.0345945273543714 GO:0032396 inhibitory MHC class I receptor activity 5/1567 13/18639 0.384615384615385 4.57488586716411 0.00302450072623563 0.0345945273543714 GO:0071714 icosanoid transmembrane transporter activity 5/1567 13/18639 0.384615384615385 4.57488586716411 0.00302450072623563 0.0345945273543714 GO:0001786 phosphatidylserine binding 12/1567 59/18639 0.203389830508475 2.41926167890712 0.00325226879808479 0.0368488191179229 GO:0005164 tumor necrosis factor receptor binding 8/1567 31/18639 0.258064516129032 3.06960083990366 0.00334431753476566 0.0375376201799398 GO:0004715 non-membrane spanning protein tyrosine kinase activity 10/1567 45/18639 0.222222222222222 2.64326738991704 0.00357468500361887 0.0397518211976506 GO:0004674 protein serine/threonine kinase activity 53/1567 433/18639 0.122401847575058 1.45593365472336 0.00361386070490068 0.0398187771246396 GO:0008514 organic anion transmembrane transporter activity 36/1567 269/18639 0.133828996282528 1.59185619764521 0.00365960187911449 0.0399561986983319 GO:0003712 transcription coregulator activity 59/1567 495/18639 0.119191919191919 1.41775250913732 0.00402285861805774 0.0432460362007763 GO:0017046 peptide hormone binding 11/1567 53/18639 0.207547169811321 2.46871199624327 0.00403293593212901 0.0432460362007763 GO:0015026 coreceptor activity 12/1567 61/18639 0.19672131147541 2.33994162386099 0.00433135194470227 0.0460349883680303 GO:0044548 S100 protein binding 5/1567 14/18639 0.357142857142857 4.24810830522381 0.00438195388123332 0.0461642685207124 GO:0016004 phospholipase activator activity 6/1567 20/18639 0.3 3.568410976388 0.00483564678123823 0.0505009720371053 GO:0019887 protein kinase regulator activity 34/1567 255/18639 0.133333333333333 1.58596043395022 0.0049212550390021 0.0509519594986338 GO:0019239 deaminase activity 8/1567 33/18639 0.242424242424242 2.88356442536404 0.00506427144514332 0.0511108403833372 GO:0140311 protein sequestering activity 8/1567 33/18639 0.242424242424242 2.88356442536404 0.00506427144514332 0.0511108403833372 GO:0140416 transcription regulator inhibitor activity 8/1567 33/18639 0.242424242424242 2.88356442536404 0.00506427144514332 0.0511108403833372 GO:0015293 symporter activity 22/1567 146/18639 0.150684931506849 1.79235254521772 0.00525216430880029 0.0525654111239096 GO:0033293 monocarboxylic acid binding 14/1567 79/18639 0.177215189873418 2.10792209575663 0.0057741988411665 0.057312502547446 GO:0015175 neutral L-amino acid transmembrane transporter activity 9/1567 41/18639 0.219512195121951 2.61103242174732 0.00609815960137361 0.0590687624053 GO:0005041 low-density lipoprotein particle receptor activity 5/1567 15/18639 0.333333333333333 3.96490108487556 0.00612300689907042 0.0590687624053 GO:0051371 muscle alpha-actinin binding 5/1567 15/18639 0.333333333333333 3.96490108487556 0.00612300689907042 0.0590687624053 GO:0001664 G protein-coupled receptor binding 38/1567 297/18639 0.127946127946128 1.52188122449769 0.00614787285650499 0.0590687624053 GO:0001217 DNA-binding transcription repressor activity 36/1567 278/18639 0.129496402877698 1.5403212847718 0.00622263396935542 0.0593125666444116 GO:0060590 ATPase regulator activity 10/1567 49/18639 0.204081632653061 2.42749046012789 0.00677757953947216 0.0640934884008352 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 4/1567 10/18639 0.4 4.75788130185067 0.00691359733107311 0.0648689874579594 GO:0008013 beta-catenin binding 17/1567 106/18639 0.160377358490566 1.90764108800616 0.00712991674085228 0.065321187191929 GO:0050698 proteoglycan sulfotransferase activity 7/1567 28/18639 0.25 2.97367581365667 0.00718105185691946 0.065321187191929 GO:0051393 alpha-actinin binding 7/1567 28/18639 0.25 2.97367581365667 0.00718105185691946 0.065321187191929 GO:0097718 disordered domain specific binding 7/1567 28/18639 0.25 2.97367581365667 0.00718105185691946 0.065321187191929 GO:0015101 organic cation transmembrane transporter activity 14/1567 81/18639 0.172839506172839 2.05587463660214 0.00723373679977232 0.065321187191929 GO:0046873 metal ion transmembrane transporter activity 53/1567 450/18639 0.117777777777778 1.40093171665603 0.00777829683973235 0.0697144366008847 GO:0015294 solute:monoatomic cation symporter activity 18/1567 116/18639 0.155172413793103 1.8457298153731 0.0080877778017625 0.0719512677030871 GO:0048029 monosaccharide binding 13/1567 74/18639 0.175675675675676 2.0896100312182 0.00824527927116816 0.072744205180224 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 5/1567 16/18639 0.3125 3.71709476707084 0.00829804838442189 0.072744205180224 GO:0043236 laminin binding 7/1567 29/18639 0.241379310344828 2.87113526835816 0.00879274949134549 0.0765224068051155 GO:0044325 transmembrane transporter binding 20/1567 136/18639 0.147058823529412 1.74922106685686 0.00982780691018665 0.0823550036564356 GO:0001046 core promoter sequence-specific DNA binding 9/1567 44/18639 0.204545454545455 2.43300748390091 0.00983358821935274 0.0823550036564356 GO:0001223 transcription coactivator binding 9/1567 44/18639 0.204545454545455 2.43300748390091 0.00983358821935274 0.0823550036564356 GO:0005543 phospholipid binding 57/1567 497/18639 0.114688128772636 1.36418125857891 0.0101069707490827 0.0823550036564356 GO:0005158 insulin receptor binding 6/1567 23/18639 0.260869565217391 3.10296606642435 0.0101321432173029 0.0823550036564356 GO:0008199 ferric iron binding 4/1567 11/18639 0.363636363636364 4.32534663804606 0.0101486599010429 0.0823550036564356 GO:0008432 JUN kinase binding 4/1567 11/18639 0.363636363636364 4.32534663804606 0.0101486599010429 0.0823550036564356 GO:0015173 aromatic amino acid transmembrane transporter activity 4/1567 11/18639 0.363636363636364 4.32534663804606 0.0101486599010429 0.0823550036564356 GO:0042608 T cell receptor binding 4/1567 11/18639 0.363636363636364 4.32534663804606 0.0101486599010429 0.0823550036564356 GO:0097493 structural molecule activity conferring elasticity 4/1567 11/18639 0.363636363636364 4.32534663804606 0.0101486599010429 0.0823550036564356 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 34/1567 268/18639 0.126865671641791 1.50902951737801 0.0103805731009462 0.0836715992901773 GO:0008429 phosphatidylethanolamine binding 5/1567 17/18639 0.294117647058824 3.49844213371373 0.0109548622011418 0.0859920882586363 GO:0008484 sulfuric ester hydrolase activity 5/1567 17/18639 0.294117647058824 3.49844213371373 0.0109548622011418 0.0859920882586363 GO:0051787 misfolded protein binding 5/1567 17/18639 0.294117647058824 3.49844213371373 0.0109548622011418 0.0859920882586363 GO:0070492 oligosaccharide binding 5/1567 17/18639 0.294117647058824 3.49844213371373 0.0109548622011418 0.0859920882586363 GO:0016209 antioxidant activity 14/1567 86/18639 0.162790697674419 1.93634704145085 0.012179568930423 0.0949848200353122 GO:0001091 RNA polymerase II general transcription initiation factor binding 6/1567 24/18639 0.25 2.97367581365667 0.0125684992052387 0.0967613304198184 GO:0019957 C-C chemokine binding 6/1567 24/18639 0.25 2.97367581365667 0.0125684992052387 0.0967613304198184 GO:0004867 serine-type endopeptidase inhibitor activity 15/1567 95/18639 0.157894736842105 1.87811104020421 0.0127018037585782 0.0971647535926909 GO:0030291 protein serine/threonine kinase inhibitor activity 9/1567 46/18639 0.195652173913043 2.32722454981826 0.0131419018935545 0.0994992900359009 GO:0097110 scaffold protein binding 12/1567 70/18639 0.171428571428571 2.03909198650743 0.0131726786975089 0.0994992900359009 GO:0015370 solute:sodium symporter activity 13/1567 79/18639 0.164556962025316 1.95735623177401 0.0140983876186695 0.102907175449757 GO:0046332 SMAD binding 13/1567 79/18639 0.164556962025316 1.95735623177401 0.0140983876186695 0.102907175449757 GO:0030228 lipoprotein particle receptor activity 5/1567 18/18639 0.277777777777778 3.3040842373963 0.014137735820951 0.102907175449757 GO:0005527 macrolide binding 4/1567 12/18639 0.333333333333333 3.96490108487556 0.0142236395709072 0.102907175449757 GO:0015132 prostaglandin transmembrane transporter activity 4/1567 12/18639 0.333333333333333 3.96490108487556 0.0142236395709072 0.102907175449757 GO:0015269 calcium-activated potassium channel activity 4/1567 12/18639 0.333333333333333 3.96490108487556 0.0142236395709072 0.102907175449757 GO:0015368 calcium:monoatomic cation antiporter activity 4/1567 12/18639 0.333333333333333 3.96490108487556 0.0142236395709072 0.102907175449757 GO:0005504 fatty acid binding 9/1567 47/18639 0.191489361702128 2.27770913386468 0.0150756982728102 0.107916460296843 GO:0005507 copper ion binding 11/1567 63/18639 0.174603174603175 2.07685294922053 0.0150957246709988 0.107916460296843 GO:0071949 FAD binding 8/1567 40/18639 0.2 2.37894065092534 0.016629175457641 0.118175382985958 GO:1990782 protein tyrosine kinase binding 17/1567 117/18639 0.145299145299145 1.72829021648422 0.0183200465960831 0.129425740952328 GO:0050750 low-density lipoprotein particle receptor binding 6/1567 26/18639 0.230769230769231 2.74493152029846 0.0186166682914268 0.129991968709323 GO:0051139 metal cation:proton antiporter activity 6/1567 26/18639 0.230769230769231 2.74493152029846 0.0186166682914268 0.129991968709323 GO:0005172 vascular endothelial growth factor receptor binding 4/1567 13/18639 0.307692307692308 3.65990869373129 0.0192010346129835 0.131025241876098 GO:0008035 high-density lipoprotein particle binding 4/1567 13/18639 0.307692307692308 3.65990869373129 0.0192010346129835 0.131025241876098 GO:0015651 quaternary ammonium group transmembrane transporter activity 4/1567 13/18639 0.307692307692308 3.65990869373129 0.0192010346129835 0.131025241876098 GO:0043560 insulin receptor substrate binding 4/1567 13/18639 0.307692307692308 3.65990869373129 0.0192010346129835 0.131025241876098 GO:0015081 sodium ion transmembrane transporter activity 22/1567 164/18639 0.134146341463415 1.59563092440114 0.0194204314700381 0.131773662121558 GO:0016763 pentosyltransferase activity 9/1567 49/18639 0.183673469387755 2.1847414141151 0.0195583706868272 0.131964062892581 GO:0008307 structural constituent of muscle 8/1567 42/18639 0.19047619047619 2.26565776278603 0.0220026685400428 0.146068635163519 GO:0051879 Hsp90 protein binding 8/1567 42/18639 0.19047619047619 2.26565776278603 0.0220026685400428 0.146068635163519 GO:0019003 GDP binding 12/1567 75/18639 0.16 1.90315252074027 0.0220136744084904 0.146068635163519 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 5/1567 20/18639 0.25 2.97367581365667 0.0222370872417767 0.146212883586814 GO:0004683 calcium/calmodulin-dependent protein kinase activity 6/1567 27/18639 0.222222222222222 2.64326738991704 0.0222788989978242 0.146212883586814 GO:0035591 signaling adaptor activity 18/1567 129/18639 0.13953488372093 1.6597260355293 0.0226625100257112 0.147922144243909 GO:0032182 ubiquitin-like protein binding 17/1567 120/18639 0.141666666666667 1.68508296107211 0.0229784844341766 0.149173836786195 GO:0051020 GTPase binding 37/1567 315/18639 0.117460317460317 1.39715562038472 0.0240069557319159 0.155012655021672 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 18/1567 130/18639 0.138461538461538 1.64695891217908 0.0243113130861524 0.15613843324315 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 4/1567 14/18639 0.285714285714286 3.39848664417905 0.0251286669056836 0.16052940932833 GO:0005319 lipid transporter activity 23/1567 178/18639 0.129213483146067 1.53695603851918 0.0255292674985158 0.162225662781574 GO:0035402 histone H3T11 kinase activity 30/1567 247/18639 0.121457489878543 1.44470080015709 0.0263616144973179 0.165115567191731 GO:0045499 chemorepellent activity 6/1567 28/18639 0.214285714285714 2.54886498313429 0.0263964936726165 0.165115567191731 GO:0046875 ephrin receptor binding 6/1567 28/18639 0.214285714285714 2.54886498313429 0.0263964936726165 0.165115567191731 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 5/1567 21/18639 0.238095238095238 2.83207220348254 0.0272188325344785 0.169377294683464 GO:0004679 AMP-activated protein kinase activity 30/1567 248/18639 0.120967741935484 1.43887539370484 0.0276651832382089 0.171267448809737 GO:0005080 protein kinase C binding 9/1567 52/18639 0.173076923076923 2.05869864022385 0.0279787567524305 0.1723204454342 GO:0030547 signaling receptor inhibitor activity 8/1567 44/18639 0.181818181818182 2.16267331902303 0.0284968828467696 0.17372972740594 GO:0043014 alpha-tubulin binding 8/1567 44/18639 0.181818181818182 2.16267331902303 0.0284968828467696 0.17372972740594 GO:0005416 amino acid:monoatomic cation symporter activity 6/1567 29/18639 0.206896551724138 2.46097308716414 0.0309887747633828 0.187967265105165 GO:0140296 general transcription initiation factor binding 9/1567 53/18639 0.169811320754717 2.01985526965359 0.0312772963597258 0.188763984562969 GO:0000774 adenyl-nucleotide exchange factor activity 4/1567 15/18639 0.266666666666667 3.17192086790045 0.0320398159989974 0.190467185769928 GO:0047372 monoacylglycerol lipase activity 4/1567 15/18639 0.266666666666667 3.17192086790045 0.0320398159989974 0.190467185769928 GO:0050700 CARD domain binding 4/1567 15/18639 0.266666666666667 3.17192086790045 0.0320398159989974 0.190467185769928 GO:0008009 chemokine activity 8/1567 45/18639 0.177777777777778 2.11461391193363 0.0321938707004957 0.190467185769928 GO:0033691 sialic acid binding 5/1567 22/18639 0.227272727272727 2.70334164877879 0.0328564558400675 0.193434330705495 GO:0015179 L-amino acid transmembrane transporter activity 10/1567 62/18639 0.161290322580645 1.91850052493979 0.0330675582995455 0.193727500086606 GO:0015297 antiporter activity 18/1567 135/18639 0.133333333333333 1.58596043395022 0.0339488142427727 0.197924883036748 GO:0031267 small GTPase binding 33/1567 283/18639 0.11660777385159 1.38701486714728 0.0345431211905886 0.20025390392723 GO:0016791 phosphatase activity 32/1567 273/18639 0.117216117216117 1.39425093094525 0.0347167655742553 0.20025390392723 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 29/1567 243/18639 0.119341563786008 1.41953248717767 0.0349868241565642 0.20025390392723 GO:0008236 serine-type peptidase activity 24/1567 194/18639 0.123711340206186 1.47150968098474 0.0360671178394953 0.20025390392723 GO:0001965 G-protein alpha-subunit binding 6/1567 30/18639 0.2 2.37894065092534 0.0360723324590164 0.20025390392723 GO:0033612 receptor serine/threonine kinase binding 6/1567 30/18639 0.2 2.37894065092534 0.0360723324590164 0.20025390392723 GO:0019210 kinase inhibitor activity 13/1567 90/18639 0.144444444444444 1.71812380344608 0.0375656970341135 0.20025390392723 GO:0004676 3-phosphoinositide-dependent protein kinase activity 29/1567 245/18639 0.118367346938776 1.40794446687418 0.0383500398861473 0.20025390392723 GO:0004711 ribosomal protein S6 kinase activity 29/1567 245/18639 0.118367346938776 1.40794446687418 0.0383500398861473 0.20025390392723 GO:0035175 histone H3S10 kinase activity 29/1567 245/18639 0.118367346938776 1.40794446687418 0.0383500398861473 0.20025390392723 GO:0035979 histone H2AXS139 kinase activity 29/1567 245/18639 0.118367346938776 1.40794446687418 0.0383500398861473 0.20025390392723 GO:0044022 histone H3S28 kinase activity 29/1567 245/18639 0.118367346938776 1.40794446687418 0.0383500398861473 0.20025390392723 GO:0044023 histone H4S1 kinase activity 29/1567 245/18639 0.118367346938776 1.40794446687418 0.0383500398861473 0.20025390392723 GO:0044024 histone H2AS1 kinase activity 29/1567 245/18639 0.118367346938776 1.40794446687418 0.0383500398861473 0.20025390392723 GO:0044025 histone H2BS14 kinase activity 29/1567 245/18639 0.118367346938776 1.40794446687418 0.0383500398861473 0.20025390392723 GO:0072354 histone H3T3 kinase activity 29/1567 245/18639 0.118367346938776 1.40794446687418 0.0383500398861473 0.20025390392723 GO:0072371 histone H2AS121 kinase activity 29/1567 245/18639 0.118367346938776 1.40794446687418 0.0383500398861473 0.20025390392723 GO:0072518 Rho-dependent protein serine/threonine kinase activity 29/1567 245/18639 0.118367346938776 1.40794446687418 0.0383500398861473 0.20025390392723 GO:0140823 histone H2BS36 kinase activity 29/1567 245/18639 0.118367346938776 1.40794446687418 0.0383500398861473 0.20025390392723 GO:0140855 histone H3S57 kinase activity 29/1567 245/18639 0.118367346938776 1.40794446687418 0.0383500398861473 0.20025390392723 GO:0140995 histone H2A kinase activity 29/1567 245/18639 0.118367346938776 1.40794446687418 0.0383500398861473 0.20025390392723 GO:0140997 histone H4 kinase activity 29/1567 245/18639 0.118367346938776 1.40794446687418 0.0383500398861473 0.20025390392723 GO:0140998 histone H2B kinase activity 29/1567 245/18639 0.118367346938776 1.40794446687418 0.0383500398861473 0.20025390392723 GO:1990244 histone H2AT120 kinase activity 29/1567 245/18639 0.118367346938776 1.40794446687418 0.0383500398861473 0.20025390392723 GO:0005283 amino acid:sodium symporter activity 5/1567 23/18639 0.217391304347826 2.58580505535362 0.0391687649019465 0.200766948979445 GO:0005149 interleukin-1 receptor binding 4/1567 16/18639 0.25 2.97367581365667 0.0399537385371893 0.200766948979445 GO:0008142 oxysterol binding 4/1567 16/18639 0.25 2.97367581365667 0.0399537385371893 0.200766948979445 GO:0015378 sodium:chloride symporter activity 4/1567 16/18639 0.25 2.97367581365667 0.0399537385371893 0.200766948979445 GO:0015385 sodium:proton antiporter activity 4/1567 16/18639 0.25 2.97367581365667 0.0399537385371893 0.200766948979445 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 4/1567 16/18639 0.25 2.97367581365667 0.0399537385371893 0.200766948979445 GO:0016722 oxidoreductase activity, acting on metal ions 4/1567 16/18639 0.25 2.97367581365667 0.0399537385371893 0.200766948979445 GO:0043130 ubiquitin binding 14/1567 100/18639 0.14 1.66525845564773 0.0400214412546399 0.200766948979445 GO:0004677 DNA-dependent protein kinase activity 29/1567 246/18639 0.117886178861789 1.40222111538282 0.0401199564988068 0.200766948979445 GO:0140857 histone H3T45 kinase activity 29/1567 246/18639 0.117886178861789 1.40222111538282 0.0401199564988068 0.200766948979445 GO:0072341 modified amino acid binding 13/1567 91/18639 0.142857142857143 1.69924332208953 0.0405897968563582 0.202275294707412 GO:0072349 modified amino acid transmembrane transporter activity 6/1567 31/18639 0.193548387096774 2.30220062992774 0.0416608858425509 0.206755057425222 GO:0035403 histone H3T6 kinase activity 29/1567 247/18639 0.117408906882591 1.39654410681852 0.041950194654968 0.207334089632167 GO:0170055 lipid transmembrane transporter activity 9/1567 56/18639 0.160714285714286 1.91164873735072 0.0427686509239434 0.210512908851049 GO:0017171 serine hydrolase activity 24/1567 198/18639 0.121212121212121 1.44178221268202 0.0441687779044985 0.214087917457071 GO:0001094 TFIID-class transcription factor complex binding 3/1567 10/18639 0.3 3.568410976388 0.0454468330190312 0.214087917457071 GO:0005131 growth hormone receptor binding 3/1567 10/18639 0.3 3.568410976388 0.0454468330190312 0.214087917457071 GO:0005528 FK506 binding 3/1567 10/18639 0.3 3.568410976388 0.0454468330190312 0.214087917457071 GO:0008519 ammonium channel activity 3/1567 10/18639 0.3 3.568410976388 0.0454468330190312 0.214087917457071 GO:0015658 branched-chain amino acid transmembrane transporter activity 3/1567 10/18639 0.3 3.568410976388 0.0454468330190312 0.214087917457071 GO:0030957 Tat protein binding 3/1567 10/18639 0.3 3.568410976388 0.0454468330190312 0.214087917457071 GO:0035256 G protein-coupled glutamate receptor binding 3/1567 10/18639 0.3 3.568410976388 0.0454468330190312 0.214087917457071 GO:0035374 chondroitin sulfate binding 3/1567 10/18639 0.3 3.568410976388 0.0454468330190312 0.214087917457071 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 3/1567 10/18639 0.3 3.568410976388 0.0454468330190312 0.214087917457071 GO:0005315 phosphate transmembrane transporter activity 5/1567 24/18639 0.208333333333333 2.47806317804722 0.0461688348221328 0.214087917457071 GO:0015149 hexose transmembrane transporter activity 5/1567 24/18639 0.208333333333333 2.47806317804722 0.0461688348221328 0.214087917457071 GO:0030215 semaphorin receptor binding 5/1567 24/18639 0.208333333333333 2.47806317804722 0.0461688348221328 0.214087917457071 GO:0055056 D-glucose transmembrane transporter activity 5/1567 24/18639 0.208333333333333 2.47806317804722 0.0461688348221328 0.214087917457071 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 5/1567 24/18639 0.208333333333333 2.47806317804722 0.0461688348221328 0.214087917457071 GO:0015144 carbohydrate transmembrane transporter activity 7/1567 40/18639 0.175 2.08157306955967 0.04706683884703 0.216141124501329 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 7/1567 40/18639 0.175 2.08157306955967 0.04706683884703 0.216141124501329 GO:0042578 phosphoric ester hydrolase activity 40/1567 363/18639 0.110192837465565 1.3107111024382 0.0471515192500819 0.216141124501329 GO:0004860 protein kinase inhibitor activity 12/1567 84/18639 0.142857142857143 1.69924332208953 0.0478664127930302 0.218583885035853 GO:0015347 sodium-independent organic anion transmembrane transporter activity 4/1567 17/18639 0.235294117647059 2.79875370697098 0.0488764697175117 0.220679098235833 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 4/1567 17/18639 0.235294117647059 2.79875370697098 0.0488764697175117 0.220679098235833 GO:0038191 neuropilin binding 4/1567 17/18639 0.235294117647059 2.79875370697098 0.0488764697175117 0.220679098235833 GO:0035254 glutamate receptor binding 8/1567 49/18639 0.163265306122449 1.94199236810231 0.0502087549762523 0.225845373507412 GO:0042169 SH2 domain binding 7/1567 41/18639 0.170731707317073 2.03080299469236 0.052807804404069 0.236649899586891 GO:0015296 monoatomic anion:monoatomic cation symporter activity 5/1567 25/18639 0.2 2.37894065092534 0.0538640607592117 0.238711206538056 GO:0015662 P-type ion transporter activity 5/1567 25/18639 0.2 2.37894065092534 0.0538640607592117 0.238711206538056 GO:0140358 P-type transmembrane transporter activity 5/1567 25/18639 0.2 2.37894065092534 0.0538640607592117 0.238711206538056 GO:0000099 sulfur amino acid transmembrane transporter activity 3/1567 11/18639 0.272727272727273 3.24400997853455 0.0586836479382767 0.252217816191152 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 3/1567 11/18639 0.272727272727273 3.24400997853455 0.0586836479382767 0.252217816191152 GO:0019215 intermediate filament binding 3/1567 11/18639 0.272727272727273 3.24400997853455 0.0586836479382767 0.252217816191152 GO:0047676 arachidonate-CoA ligase activity 3/1567 11/18639 0.272727272727273 3.24400997853455 0.0586836479382767 0.252217816191152 GO:0140537 transcription regulator activator activity 3/1567 11/18639 0.272727272727273 3.24400997853455 0.0586836479382767 0.252217816191152 GO:0008525 phosphatidylcholine transporter activity 4/1567 18/18639 0.222222222222222 2.64326738991704 0.0588018222593861 0.252217816191152 GO:0015172 acidic amino acid transmembrane transporter activity 4/1567 18/18639 0.222222222222222 2.64326738991704 0.0588018222593861 0.252217816191152 GO:0015373 monoatomic anion:sodium symporter activity 4/1567 18/18639 0.222222222222222 2.64326738991704 0.0588018222593861 0.252217816191152 GO:0034185 apolipoprotein binding 4/1567 18/18639 0.222222222222222 2.64326738991704 0.0588018222593861 0.252217816191152 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 38/1567 349/18639 0.108882521489971 1.29512528273872 0.0599969131683906 0.256428087954581 GO:0030544 Hsp70 protein binding 8/1567 51/18639 0.156862745098039 1.86583580464732 0.0612549946015839 0.257826940587377 GO:0140297 DNA-binding transcription factor binding 51/1567 488/18639 0.104508196721311 1.24309398767615 0.0619896573259275 0.257826940587377 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 5/1567 26/18639 0.192307692307692 2.28744293358205 0.0622562970610652 0.257826940587377 GO:0008157 protein phosphatase 1 binding 5/1567 26/18639 0.192307692307692 2.28744293358205 0.0622562970610652 0.257826940587377 GO:0008198 ferrous iron binding 5/1567 26/18639 0.192307692307692 2.28744293358205 0.0622562970610652 0.257826940587377 GO:0015145 monosaccharide transmembrane transporter activity 5/1567 26/18639 0.192307692307692 2.28744293358205 0.0622562970610652 0.257826940587377 GO:0019865 immunoglobulin binding 5/1567 26/18639 0.192307692307692 2.28744293358205 0.0622562970610652 0.257826940587377 GO:0030247 polysaccharide binding 5/1567 26/18639 0.192307692307692 2.28744293358205 0.0622562970610652 0.257826940587377 GO:0043548 phosphatidylinositol 3-kinase binding 5/1567 26/18639 0.192307692307692 2.28744293358205 0.0622562970610652 0.257826940587377 GO:0030695 GTPase regulator activity 51/1567 489/18639 0.104294478527607 1.24055187318192 0.0637808396586139 0.263232949931255 GO:0060589 nucleoside-triphosphatase regulator activity 51/1567 490/18639 0.104081632653061 1.23802013466523 0.0656093785574148 0.269852272765257 GO:0004175 endopeptidase activity 43/1567 405/18639 0.106172839506173 1.26289441962703 0.0665363936276342 0.272219234548173 GO:0042626 ATPase-coupled transmembrane transporter activity 13/1567 98/18639 0.13265306122449 1.57786879908313 0.0666381806470965 0.272219234548173 GO:0008028 monocarboxylic acid transmembrane transporter activity 10/1567 70/18639 0.142857142857143 1.69924332208953 0.0670318079001342 0.272898987417156 GO:0015085 calcium ion transmembrane transporter activity 18/1567 147/18639 0.122448979591837 1.45649427607674 0.0680565479182224 0.274507310387004 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 12/1567 89/18639 0.134831460674157 1.60378021410697 0.0688292493958127 0.274507310387004 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 12/1567 89/18639 0.134831460674157 1.60378021410697 0.0688292493958127 0.274507310387004 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 4/1567 19/18639 0.210526315789474 2.50414805360562 0.0697125142947846 0.274507310387004 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 4/1567 19/18639 0.210526315789474 2.50414805360562 0.0697125142947846 0.274507310387004 GO:0022821 solute:potassium antiporter activity 4/1567 19/18639 0.210526315789474 2.50414805360562 0.0697125142947846 0.274507310387004 GO:0030506 ankyrin binding 4/1567 19/18639 0.210526315789474 2.50414805360562 0.0697125142947846 0.274507310387004 GO:0034987 immunoglobulin receptor binding 4/1567 19/18639 0.210526315789474 2.50414805360562 0.0697125142947846 0.274507310387004 GO:0043395 heparan sulfate proteoglycan binding 4/1567 19/18639 0.210526315789474 2.50414805360562 0.0697125142947846 0.274507310387004 GO:0097001 ceramide binding 4/1567 19/18639 0.210526315789474 2.50414805360562 0.0697125142947846 0.274507310387004 GO:0001671 ATPase activator activity 5/1567 27/18639 0.185185185185185 2.20272282493087 0.0713420693481654 0.274925250787869 GO:0005044 scavenger receptor activity 5/1567 27/18639 0.185185185185185 2.20272282493087 0.0713420693481654 0.274925250787869 GO:0000340 RNA 7-methylguanosine cap binding 3/1567 12/18639 0.25 2.97367581365667 0.0735036507274 0.274925250787869 GO:0004859 phospholipase inhibitor activity 3/1567 12/18639 0.25 2.97367581365667 0.0735036507274 0.274925250787869 GO:0005078 MAP-kinase scaffold activity 3/1567 12/18639 0.25 2.97367581365667 0.0735036507274 0.274925250787869 GO:0015166 polyol transmembrane transporter activity 3/1567 12/18639 0.25 2.97367581365667 0.0735036507274 0.274925250787869 GO:0016208 AMP binding 3/1567 12/18639 0.25 2.97367581365667 0.0735036507274 0.274925250787869 GO:0016840 carbon-nitrogen lyase activity 3/1567 12/18639 0.25 2.97367581365667 0.0735036507274 0.274925250787869 GO:0031543 peptidyl-proline dioxygenase activity 3/1567 12/18639 0.25 2.97367581365667 0.0735036507274 0.274925250787869 GO:0042301 phosphate ion binding 3/1567 12/18639 0.25 2.97367581365667 0.0735036507274 0.274925250787869 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 3/1567 12/18639 0.25 2.97367581365667 0.0735036507274 0.274925250787869 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 3/1567 12/18639 0.25 2.97367581365667 0.0735036507274 0.274925250787869 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 3/1567 12/18639 0.25 2.97367581365667 0.0735036507274 0.274925250787869 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 3/1567 12/18639 0.25 2.97367581365667 0.0735036507274 0.274925250787869 GO:0140793 histone H2AXY142 phosphatase activity 12/1567 90/18639 0.133333333333333 1.58596043395022 0.0736390266822279 0.274925250787869 GO:0008146 sulfotransferase activity 8/1567 53/18639 0.150943396226415 1.79542690635874 0.073710183808238 0.274925250787869 GO:0038064 collagen receptor activity 8/1567 53/18639 0.150943396226415 1.79542690635874 0.073710183808238 0.274925250787869 GO:0000287 magnesium ion binding 26/1567 230/18639 0.11304347826087 1.34461862878389 0.0746069555110789 0.277408524980823 GO:0004222 metalloendopeptidase activity 14/1567 110/18639 0.127272727272727 1.51387132331612 0.0772379362680257 0.286304819314503 GO:0019842 vitamin binding 18/1567 150/18639 0.12 1.4273643905552 0.0793062237286279 0.293066999071022 GO:0046915 transition metal ion transmembrane transporter activity 7/1567 45/18639 0.155555555555556 1.85028717294193 0.0800011997148362 0.294728346188706 GO:0046625 sphingolipid binding 5/1567 28/18639 0.178571428571429 2.12405415261191 0.081112846668937 0.297001612345711 GO:0051119 sugar transmembrane transporter activity 5/1567 28/18639 0.178571428571429 2.12405415261191 0.081112846668937 0.297001612345711 GO:0031418 L-ascorbic acid binding 4/1567 20/18639 0.2 2.37894065092534 0.0815813710580364 0.297809199515811 GO:0043539 protein serine/threonine kinase activator activity 10/1567 73/18639 0.136986301369863 1.62941140474338 0.0840149860160799 0.305763630925188 GO:0015171 amino acid transmembrane transporter activity 13/1567 102/18639 0.127450980392157 1.51599159127595 0.0855928073224131 0.310564838653227 GO:0005200 structural constituent of cytoskeleton 14/1567 112/18639 0.125 1.48683790682833 0.0867188676911843 0.313702891858772 GO:0030165 PDZ domain binding 11/1567 83/18639 0.132530120481928 1.57640645543245 0.087139478970904 0.31427782055272 GO:0004465 lipoprotein lipase activity 3/1567 13/18639 0.230769230769231 2.74493152029846 0.0897944355617249 0.318121289408943 GO:0019855 calcium channel inhibitor activity 3/1567 13/18639 0.230769230769231 2.74493152029846 0.0897944355617249 0.318121289408943 GO:0030955 potassium ion binding 3/1567 13/18639 0.230769230769231 2.74493152029846 0.0897944355617249 0.318121289408943 GO:0070700 BMP receptor binding 3/1567 13/18639 0.230769230769231 2.74493152029846 0.0897944355617249 0.318121289408943 GO:0140333 glycerophospholipid flippase activity 3/1567 13/18639 0.230769230769231 2.74493152029846 0.0897944355617249 0.318121289408943 GO:0140410 monoatomic cation:bicarbonate symporter activity 3/1567 13/18639 0.230769230769231 2.74493152029846 0.0897944355617249 0.318121289408943 GO:0051861 glycolipid binding 5/1567 29/18639 0.172413793103448 2.05081090597012 0.0915553616492606 0.323405851002241 GO:0016757 glycosyltransferase activity 29/1567 267/18639 0.108614232209738 1.29193406136395 0.0926629151857761 0.326358243806795 GO:0051117 ATPase binding 11/1567 84/18639 0.130952380952381 1.5576397119154 0.0930573382579808 0.326789073824079 GO:0009931 calcium-dependent protein serine/threonine kinase activity 4/1567 21/18639 0.19047619047619 2.26565776278603 0.0943725565929913 0.329480931593554 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 4/1567 21/18639 0.19047619047619 2.26565776278603 0.0943725565929913 0.329480931593554 GO:0140359 ABC-type transporter activity 7/1567 47/18639 0.148936170212766 1.77155154856142 0.0961436326400422 0.33469131246577 GO:0035925 mRNA 3'-UTR AU-rich region binding 5/1567 30/18639 0.166666666666667 1.98245054243778 0.10265196748731 0.354307113860193 GO:0048019 receptor antagonist activity 5/1567 30/18639 0.166666666666667 1.98245054243778 0.10265196748731 0.354307113860193 GO:0016504 peptidase activator activity 8/1567 57/18639 0.140350877192982 1.66943203573708 0.102877044590321 0.354307113860193 GO:0004252 serine-type endopeptidase activity 20/1567 176/18639 0.113636363636364 1.35167082438939 0.102958520180855 0.354307113860193 GO:0038187 pattern recognition receptor activity 7/1567 48/18639 0.145833333333333 1.73464422463306 0.104840538841579 0.356481879799196 GO:0140693 molecular condensate scaffold activity 7/1567 48/18639 0.145833333333333 1.73464422463306 0.104840538841579 0.356481879799196 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 6/1567 39/18639 0.153846153846154 1.82995434686564 0.105208918050146 0.356481879799196 GO:0050660 flavin adenine dinucleotide binding 11/1567 86/18639 0.127906976744186 1.52141553256853 0.105601458685334 0.356481879799196 GO:0005096 GTPase activator activity 29/1567 271/18639 0.107011070110701 1.27286492392684 0.106316696294873 0.356481879799196 GO:0004065 arylsulfatase activity 3/1567 14/18639 0.214285714285714 2.54886498313429 0.1074305542861 0.356481879799196 GO:0005347 ATP transmembrane transporter activity 3/1567 14/18639 0.214285714285714 2.54886498313429 0.1074305542861 0.356481879799196 GO:0008191 metalloendopeptidase inhibitor activity 3/1567 14/18639 0.214285714285714 2.54886498313429 0.1074305542861 0.356481879799196 GO:0015386 potassium:proton antiporter activity 3/1567 14/18639 0.214285714285714 2.54886498313429 0.1074305542861 0.356481879799196 GO:0046030 inositol trisphosphate phosphatase activity 3/1567 14/18639 0.214285714285714 2.54886498313429 0.1074305542861 0.356481879799196 GO:0071933 Arp2/3 complex binding 3/1567 14/18639 0.214285714285714 2.54886498313429 0.1074305542861 0.356481879799196 GO:1901474 azole transmembrane transporter activity 3/1567 14/18639 0.214285714285714 2.54886498313429 0.1074305542861 0.356481879799196 GO:0008970 phospholipase A1 activity 4/1567 22/18639 0.181818181818182 2.16267331902303 0.108042801204752 0.356481879799196 GO:0015377 chloride:monoatomic cation symporter activity 4/1567 22/18639 0.181818181818182 2.16267331902303 0.108042801204752 0.356481879799196 GO:0061133 endopeptidase activator activity 4/1567 22/18639 0.181818181818182 2.16267331902303 0.108042801204752 0.356481879799196 GO:0046943 carboxylic acid transmembrane transporter activity 21/1567 188/18639 0.111702127659574 1.32866366142106 0.110258172453325 0.362794698949159 GO:0005342 organic acid transmembrane transporter activity 21/1567 189/18639 0.111111111111111 1.32163369495852 0.114738675177598 0.373796795813963 GO:0032934 sterol binding 9/1567 68/18639 0.132352941176471 1.57429896017118 0.115092181179635 0.373796795813963 GO:1990841 promoter-specific chromatin binding 9/1567 68/18639 0.132352941176471 1.57429896017118 0.115092181179635 0.373796795813963 GO:0050997 quaternary ammonium group binding 6/1567 40/18639 0.15 1.784205488194 0.115469284968343 0.373796795813963 GO:0061791 GTPase motor activity 6/1567 40/18639 0.15 1.784205488194 0.115469284968343 0.373796795813963 GO:1990606 membrane scission GTPase motor activity 6/1567 40/18639 0.15 1.784205488194 0.115469284968343 0.373796795813963 GO:0004197 cysteine-type endopeptidase activity 11/1567 88/18639 0.125 1.48683790682833 0.119082468220473 0.384457108421473 GO:0004725 protein tyrosine phosphatase activity 12/1567 98/18639 0.122448979591837 1.45649427607674 0.119735071767624 0.385527670758488 GO:0004602 glutathione peroxidase activity 4/1567 23/18639 0.173913043478261 2.0686440442829 0.122542598321132 0.39038106255618 GO:0016493 C-C chemokine receptor activity 4/1567 23/18639 0.173913043478261 2.0686440442829 0.122542598321132 0.39038106255618 GO:0017134 fibroblast growth factor binding 4/1567 23/18639 0.173913043478261 2.0686440442829 0.122542598321132 0.39038106255618 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 4/1567 23/18639 0.173913043478261 2.0686440442829 0.122542598321132 0.39038106255618 GO:0001530 lipopolysaccharide binding 6/1567 41/18639 0.146341463414634 1.74068828116488 0.126211253065076 0.39324925551565 GO:0004467 long-chain fatty acid-CoA ligase activity 3/1567 15/18639 0.2 2.37894065092534 0.126278238857876 0.39324925551565 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 3/1567 15/18639 0.2 2.37894065092534 0.126278238857876 0.39324925551565 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 3/1567 15/18639 0.2 2.37894065092534 0.126278238857876 0.39324925551565 GO:0004953 icosanoid receptor activity 3/1567 15/18639 0.2 2.37894065092534 0.126278238857876 0.39324925551565 GO:0034483 heparan sulfate sulfotransferase activity 3/1567 15/18639 0.2 2.37894065092534 0.126278238857876 0.39324925551565 GO:0120283 protein serine/threonine kinase binding 3/1567 15/18639 0.2 2.37894065092534 0.126278238857876 0.39324925551565 GO:0140776 protein-containing complex destabilizing activity 3/1567 15/18639 0.2 2.37894065092534 0.126278238857876 0.39324925551565 GO:0042910 xenobiotic transmembrane transporter activity 5/1567 32/18639 0.15625 1.85854738353542 0.126717287164493 0.39324925551565 GO:0051059 NF-kappaB binding 5/1567 32/18639 0.15625 1.85854738353542 0.126717287164493 0.39324925551565 GO:0015631 tubulin binding 39/1567 385/18639 0.101298701298701 1.20491799202712 0.128734867408888 0.398480865355861 GO:0003713 transcription coactivator activity 27/1567 256/18639 0.10546875 1.25451948388641 0.130764263231796 0.403722056918731 GO:0016782 transferase activity, transferring sulphur-containing groups 9/1567 70/18639 0.128571428571429 1.52931898988057 0.131339156447027 0.40445724844328 GO:0048487 beta-tubulin binding 6/1567 42/18639 0.142857142857143 1.69924332208953 0.13741832331311 0.414793699715027 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 4/1567 24/18639 0.166666666666667 1.98245054243778 0.137817351020932 0.414793699715027 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 4/1567 24/18639 0.166666666666667 1.98245054243778 0.137817351020932 0.414793699715027 GO:0004806 triacylglycerol lipase activity 4/1567 24/18639 0.166666666666667 1.98245054243778 0.137817351020932 0.414793699715027 GO:0005540 hyaluronic acid binding 4/1567 24/18639 0.166666666666667 1.98245054243778 0.137817351020932 0.414793699715027 GO:0030552 cAMP binding 4/1567 24/18639 0.166666666666667 1.98245054243778 0.137817351020932 0.414793699715027 GO:0035035 histone acetyltransferase binding 4/1567 24/18639 0.166666666666667 1.98245054243778 0.137817351020932 0.414793699715027 GO:0050431 transforming growth factor beta binding 4/1567 24/18639 0.166666666666667 1.98245054243778 0.137817351020932 0.414793699715027 GO:0030296 protein tyrosine kinase activator activity 5/1567 33/18639 0.151515151515152 1.80222776585253 0.139632343445836 0.414793699715027 GO:0030971 receptor tyrosine kinase binding 10/1567 81/18639 0.123456790123457 1.46848188328724 0.140912430877378 0.414793699715027 GO:0033192 calmodulin-dependent protein phosphatase activity 10/1567 81/18639 0.123456790123457 1.46848188328724 0.140912430877378 0.414793699715027 GO:0140791 histone H2AXS140 phosphatase activity 10/1567 81/18639 0.123456790123457 1.46848188328724 0.140912430877378 0.414793699715027 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 10/1567 81/18639 0.123456790123457 1.46848188328724 0.140912430877378 0.414793699715027 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 10/1567 81/18639 0.123456790123457 1.46848188328724 0.140912430877378 0.414793699715027 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 10/1567 81/18639 0.123456790123457 1.46848188328724 0.140912430877378 0.414793699715027 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 10/1567 81/18639 0.123456790123457 1.46848188328724 0.140912430877378 0.414793699715027 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 10/1567 81/18639 0.123456790123457 1.46848188328724 0.140912430877378 0.414793699715027 GO:1990439 MAP kinase serine/threonine phosphatase activity 10/1567 81/18639 0.123456790123457 1.46848188328724 0.140912430877378 0.414793699715027 GO:0003774 cytoskeletal motor activity 17/1567 153/18639 0.111111111111111 1.32163369495852 0.14418264874801 0.423382301091344 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 3/1567 16/18639 0.1875 2.2302568602425 0.146199277393419 0.42514608268643 GO:0070411 I-SMAD binding 3/1567 16/18639 0.1875 2.2302568602425 0.146199277393419 0.42514608268643 GO:0140327 flippase activity 3/1567 16/18639 0.1875 2.2302568602425 0.146199277393419 0.42514608268643 GO:0140328 floppase activity 3/1567 16/18639 0.1875 2.2302568602425 0.146199277393419 0.42514608268643 GO:0004712 protein serine/threonine/tyrosine kinase activity 6/1567 43/18639 0.13953488372093 1.6597260355293 0.149072038526274 0.429623795498596 GO:0048156 tau protein binding 6/1567 43/18639 0.13953488372093 1.6597260355293 0.149072038526274 0.429623795498596 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 10/1567 82/18639 0.121951219512195 1.4505735676374 0.149169960635233 0.429623795498596 GO:0033549 MAP kinase phosphatase activity 10/1567 82/18639 0.121951219512195 1.4505735676374 0.149169960635233 0.429623795498596 GO:0008376 acetylgalactosaminyltransferase activity 5/1567 34/18639 0.147058823529412 1.74922106685686 0.153094999607093 0.431847633301941 GO:0051427 hormone receptor binding 5/1567 34/18639 0.147058823529412 1.74922106685686 0.153094999607093 0.431847633301941 GO:0090482 vitamin transmembrane transporter activity 5/1567 34/18639 0.147058823529412 1.74922106685686 0.153094999607093 0.431847633301941 GO:0003707 nuclear steroid receptor activity 4/1567 25/18639 0.16 1.90315252074027 0.153808453927927 0.431847633301941 GO:0017025 TBP-class protein binding 4/1567 25/18639 0.16 1.90315252074027 0.153808453927927 0.431847633301941 GO:0019211 phosphatase activator activity 4/1567 25/18639 0.16 1.90315252074027 0.153808453927927 0.431847633301941 GO:0042974 nuclear retinoic acid receptor binding 4/1567 25/18639 0.16 1.90315252074027 0.153808453927927 0.431847633301941 GO:0047617 fatty acyl-CoA hydrolase activity 4/1567 25/18639 0.16 1.90315252074027 0.153808453927927 0.431847633301941 GO:0120020 cholesterol transfer activity 4/1567 25/18639 0.16 1.90315252074027 0.153808453927927 0.431847633301941 GO:0005246 calcium channel regulator activity 7/1567 53/18639 0.132075471698113 1.5709985430639 0.154256981420926 0.431847633301941 GO:0005544 calcium-dependent phospholipid binding 7/1567 53/18639 0.132075471698113 1.5709985430639 0.154256981420926 0.431847633301941 GO:1901505 carbohydrate derivative transmembrane transporter activity 7/1567 53/18639 0.132075471698113 1.5709985430639 0.154256981420926 0.431847633301941 GO:0051219 phosphoprotein binding 11/1567 93/18639 0.118279569892473 1.40690038495584 0.156755266947801 0.437110997822637 GO:1901682 sulfur compound transmembrane transporter activity 8/1567 63/18639 0.126984126984127 1.51043850852402 0.156864979235268 0.437110997822637 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 10/1567 83/18639 0.120481927710843 1.43309677766586 0.15766728689062 0.438329656378784 GO:0005085 guanyl-nucleotide exchange factor activity 24/1567 230/18639 0.104347826086957 1.24118642656974 0.159304828709651 0.440916740413457 GO:0008194 UDP-glycosyltransferase activity 16/1567 145/18639 0.110344827586207 1.31251897982087 0.159332111023681 0.440916740413457 GO:0003925 G protein activity 7/1567 54/18639 0.12962962962963 1.54190597745161 0.165246411159938 0.45090588030462 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 7/1567 54/18639 0.12962962962963 1.54190597745161 0.165246411159938 0.45090588030462 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 7/1567 54/18639 0.12962962962963 1.54190597745161 0.165246411159938 0.45090588030462 GO:0051287 NAD binding 7/1567 54/18639 0.12962962962963 1.54190597745161 0.165246411159938 0.45090588030462 GO:0017018 myosin phosphatase activity 10/1567 84/18639 0.119047619047619 1.41603610174127 0.166398361030166 0.45090588030462 GO:0004029 aldehyde dehydrogenase (NAD+) activity 3/1567 17/18639 0.176470588235294 2.09906528022824 0.167054164752541 0.45090588030462 GO:0008569 minus-end-directed microtubule motor activity 3/1567 17/18639 0.176470588235294 2.09906528022824 0.167054164752541 0.45090588030462 GO:0046965 nuclear retinoid X receptor binding 3/1567 17/18639 0.176470588235294 2.09906528022824 0.167054164752541 0.45090588030462 GO:0070403 NAD+ binding 3/1567 17/18639 0.176470588235294 2.09906528022824 0.167054164752541 0.45090588030462 GO:0005343 organic acid:sodium symporter activity 5/1567 35/18639 0.142857142857143 1.69924332208953 0.167071704192803 0.45090588030462 GO:0061631 ubiquitin conjugating enzyme activity 5/1567 35/18639 0.142857142857143 1.69924332208953 0.167071704192803 0.45090588030462 GO:0001637 G protein-coupled chemoattractant receptor activity 4/1567 26/18639 0.153846153846154 1.82995434686564 0.170454300630992 0.452910652782791 GO:0004112 cyclic-nucleotide phosphodiesterase activity 4/1567 26/18639 0.153846153846154 1.82995434686564 0.170454300630992 0.452910652782791 GO:0004950 chemokine receptor activity 4/1567 26/18639 0.153846153846154 1.82995434686564 0.170454300630992 0.452910652782791 GO:0005160 transforming growth factor beta receptor binding 4/1567 26/18639 0.153846153846154 1.82995434686564 0.170454300630992 0.452910652782791 GO:0005227 calcium-activated cation channel activity 4/1567 26/18639 0.153846153846154 1.82995434686564 0.170454300630992 0.452910652782791 GO:0008143 poly(A) binding 4/1567 26/18639 0.153846153846154 1.82995434686564 0.170454300630992 0.452910652782791 GO:0016289 acyl-CoA hydrolase activity 4/1567 26/18639 0.153846153846154 1.82995434686564 0.170454300630992 0.452910652782791 GO:0140303 intramembrane lipid transporter activity 6/1567 45/18639 0.133333333333333 1.58596043395022 0.17363694105441 0.459334727326755 GO:0141110 transporter inhibitor activity 6/1567 45/18639 0.133333333333333 1.58596043395022 0.17363694105441 0.459334727326755 GO:0016922 nuclear receptor binding 15/1567 137/18639 0.109489051094891 1.30233977240438 0.176247898598884 0.465216980697274 GO:0004869 cysteine-type endopeptidase inhibitor activity 5/1567 36/18639 0.138888888888889 1.65204211869815 0.181526946187653 0.47705440343845 GO:0044390 ubiquitin-like protein conjugating enzyme binding 5/1567 36/18639 0.138888888888889 1.65204211869815 0.181526946187653 0.47705440343845 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 19/1567 181/18639 0.104972375690608 1.24861525877297 0.185967313945828 0.487656646395064 GO:0008266 poly(U) RNA binding 4/1567 27/18639 0.148148148148148 1.76217825994469 0.18769121041931 0.489490852126692 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 4/1567 27/18639 0.148148148148148 1.76217825994469 0.18769121041931 0.489490852126692 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 3/1567 18/18639 0.166666666666667 1.98245054243778 0.188704633251173 0.489490852126692 GO:0016854 racemase and epimerase activity 3/1567 18/18639 0.166666666666667 1.98245054243778 0.188704633251173 0.489490852126692 GO:0098641 cadherin binding involved in cell-cell adhesion 3/1567 18/18639 0.166666666666667 1.98245054243778 0.188704633251173 0.489490852126692 GO:0005496 steroid binding 12/1567 108/18639 0.111111111111111 1.32163369495852 0.195684411337619 0.497585206344524 GO:0070001 aspartic-type peptidase activity 5/1567 37/18639 0.135135135135135 1.60739233170631 0.196423643020881 0.497585206344524 GO:0004601 peroxidase activity 7/1567 57/18639 0.12280701754386 1.46075303126994 0.200164393316807 0.497585206344524 GO:0016298 lipase activity 14/1567 130/18639 0.107692307692308 1.28096804280595 0.202996598221754 0.497585206344524 GO:0016798 hydrolase activity, acting on glycosyl bonds 14/1567 130/18639 0.107692307692308 1.28096804280595 0.202996598221754 0.497585206344524 GO:0000182 rDNA binding 2/1567 10/18639 0.2 2.37894065092534 0.203011449715917 0.497585206344524 GO:0004382 GDP phosphatase activity 2/1567 10/18639 0.2 2.37894065092534 0.203011449715917 0.497585206344524 GO:0004445 inositol-polyphosphate 5-phosphatase activity 2/1567 10/18639 0.2 2.37894065092534 0.203011449715917 0.497585206344524 GO:0004862 cAMP-dependent protein kinase inhibitor activity 2/1567 10/18639 0.2 2.37894065092534 0.203011449715917 0.497585206344524 GO:0004935 adrenergic receptor activity 2/1567 10/18639 0.2 2.37894065092534 0.203011449715917 0.497585206344524 GO:0004955 prostaglandin receptor activity 2/1567 10/18639 0.2 2.37894065092534 0.203011449715917 0.497585206344524 GO:0005345 purine nucleobase transmembrane transporter activity 2/1567 10/18639 0.2 2.37894065092534 0.203011449715917 0.497585206344524 GO:0005381 iron ion transmembrane transporter activity 2/1567 10/18639 0.2 2.37894065092534 0.203011449715917 0.497585206344524 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 2/1567 10/18639 0.2 2.37894065092534 0.203011449715917 0.497585206344524 GO:0015187 glycine transmembrane transporter activity 2/1567 10/18639 0.2 2.37894065092534 0.203011449715917 0.497585206344524 GO:0015203 polyamine transmembrane transporter activity 2/1567 10/18639 0.2 2.37894065092534 0.203011449715917 0.497585206344524 GO:0015279 store-operated calcium channel activity 2/1567 10/18639 0.2 2.37894065092534 0.203011449715917 0.497585206344524 GO:0015643 toxic substance binding 2/1567 10/18639 0.2 2.37894065092534 0.203011449715917 0.497585206344524 GO:0016427 tRNA (cytidine) methyltransferase activity 2/1567 10/18639 0.2 2.37894065092534 0.203011449715917 0.497585206344524 GO:0031419 cobalamin binding 2/1567 10/18639 0.2 2.37894065092534 0.203011449715917 0.497585206344524 GO:0031996 thioesterase binding 2/1567 10/18639 0.2 2.37894065092534 0.203011449715917 0.497585206344524 GO:0042975 peroxisome proliferator activated receptor binding 2/1567 10/18639 0.2 2.37894065092534 0.203011449715917 0.497585206344524 GO:0043208 glycosphingolipid binding 2/1567 10/18639 0.2 2.37894065092534 0.203011449715917 0.497585206344524 GO:0043422 protein kinase B binding 2/1567 10/18639 0.2 2.37894065092534 0.203011449715917 0.497585206344524 GO:0050308 sugar-phosphatase activity 2/1567 10/18639 0.2 2.37894065092534 0.203011449715917 0.497585206344524 GO:0070513 death domain binding 2/1567 10/18639 0.2 2.37894065092534 0.203011449715917 0.497585206344524 GO:1905394 retromer complex binding 2/1567 10/18639 0.2 2.37894065092534 0.203011449715917 0.497585206344524 GO:0008237 metallopeptidase activity 19/1567 184/18639 0.103260869565217 1.22825740129297 0.205413900823128 0.500508274897142 GO:0046966 nuclear thyroid hormone receptor binding 4/1567 28/18639 0.142857142857143 1.69924332208953 0.205454271044372 0.500508274897142 GO:0051959 dynein light intermediate chain binding 4/1567 28/18639 0.142857142857143 1.69924332208953 0.205454271044372 0.500508274897142 GO:0005346 purine ribonucleotide transmembrane transporter activity 3/1567 19/18639 0.157894736842105 1.87811104020421 0.211015655555495 0.507544786441588 GO:0015245 fatty acid transmembrane transporter activity 3/1567 19/18639 0.157894736842105 1.87811104020421 0.211015655555495 0.507544786441588 GO:0016918 retinal binding 3/1567 19/18639 0.157894736842105 1.87811104020421 0.211015655555495 0.507544786441588 GO:0031420 alkali metal ion binding 3/1567 19/18639 0.157894736842105 1.87811104020421 0.211015655555495 0.507544786441588 GO:0042577 lipid phosphatase activity 3/1567 19/18639 0.157894736842105 1.87811104020421 0.211015655555495 0.507544786441588 GO:0050145 nucleoside monophosphate kinase activity 3/1567 19/18639 0.157894736842105 1.87811104020421 0.211015655555495 0.507544786441588 GO:0005501 retinoid binding 5/1567 38/18639 0.131578947368421 1.56509253350351 0.211723512079297 0.507544786441588 GO:0019840 isoprenoid binding 5/1567 38/18639 0.131578947368421 1.56509253350351 0.211723512079297 0.507544786441588 GO:0004540 RNA nuclease activity 13/1567 121/18639 0.107438016528926 1.27794332487725 0.216396398957619 0.51771329710777 GO:0035250 UDP-galactosyltransferase activity 4/1567 29/18639 0.137931034482759 1.64064872477609 0.22367809654759 0.528719546368964 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 7/1567 59/18639 0.11864406779661 1.41123597936249 0.224894602432259 0.528719546368964 GO:0070888 E-box binding 7/1567 59/18639 0.11864406779661 1.41123597936249 0.224894602432259 0.528719546368964 GO:0008234 cysteine-type peptidase activity 19/1567 187/18639 0.101604278074866 1.20855273710111 0.225776257730146 0.528719546368964 GO:0016776 phosphotransferase activity, phosphate group as acceptor 5/1567 39/18639 0.128205128205128 1.52496195572137 0.227387422965937 0.528719546368964 GO:0000339 RNA cap binding 3/1567 20/18639 0.15 1.784205488194 0.233856999878576 0.528719546368964 GO:0001614 purinergic nucleotide receptor activity 3/1567 20/18639 0.15 1.784205488194 0.233856999878576 0.528719546368964 GO:0010851 cyclase regulator activity 3/1567 20/18639 0.15 1.784205488194 0.233856999878576 0.528719546368964 GO:0016502 nucleotide receptor activity 3/1567 20/18639 0.15 1.784205488194 0.233856999878576 0.528719546368964 GO:0052745 inositol phosphate phosphatase activity 3/1567 20/18639 0.15 1.784205488194 0.233856999878576 0.528719546368964 GO:0002162 dystroglycan binding 2/1567 11/18639 0.181818181818182 2.16267331902303 0.235084294555393 0.528719546368964 GO:0004016 adenylate cyclase activity 2/1567 11/18639 0.181818181818182 2.16267331902303 0.235084294555393 0.528719546368964 GO:0004954 prostanoid receptor activity 2/1567 11/18639 0.181818181818182 2.16267331902303 0.235084294555393 0.528719546368964 GO:0005225 volume-sensitive anion channel activity 2/1567 11/18639 0.181818181818182 2.16267331902303 0.235084294555393 0.528719546368964 GO:0005536 D-glucose binding 2/1567 11/18639 0.181818181818182 2.16267331902303 0.235084294555393 0.528719546368964 GO:0010854 adenylate cyclase regulator activity 2/1567 11/18639 0.181818181818182 2.16267331902303 0.235084294555393 0.528719546368964 GO:0015205 nucleobase transmembrane transporter activity 2/1567 11/18639 0.181818181818182 2.16267331902303 0.235084294555393 0.528719546368964 GO:0016176 superoxide-generating NADPH oxidase activator activity 2/1567 11/18639 0.181818181818182 2.16267331902303 0.235084294555393 0.528719546368964 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 2/1567 11/18639 0.181818181818182 2.16267331902303 0.235084294555393 0.528719546368964 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 2/1567 11/18639 0.181818181818182 2.16267331902303 0.235084294555393 0.528719546368964 GO:0019107 myristoyltransferase activity 2/1567 11/18639 0.181818181818182 2.16267331902303 0.235084294555393 0.528719546368964 GO:0019203 carbohydrate phosphatase activity 2/1567 11/18639 0.181818181818182 2.16267331902303 0.235084294555393 0.528719546368964 GO:0019206 nucleoside kinase activity 2/1567 11/18639 0.181818181818182 2.16267331902303 0.235084294555393 0.528719546368964 GO:0031731 CCR6 chemokine receptor binding 2/1567 11/18639 0.181818181818182 2.16267331902303 0.235084294555393 0.528719546368964 GO:0034713 type I transforming growth factor beta receptor binding 2/1567 11/18639 0.181818181818182 2.16267331902303 0.235084294555393 0.528719546368964 GO:0043522 leucine zipper domain binding 2/1567 11/18639 0.181818181818182 2.16267331902303 0.235084294555393 0.528719546368964 GO:0045294 alpha-catenin binding 2/1567 11/18639 0.181818181818182 2.16267331902303 0.235084294555393 0.528719546368964 GO:0048407 platelet-derived growth factor binding 2/1567 11/18639 0.181818181818182 2.16267331902303 0.235084294555393 0.528719546368964 GO:0050786 RAGE receptor binding 2/1567 11/18639 0.181818181818182 2.16267331902303 0.235084294555393 0.528719546368964 GO:0070697 activin receptor binding 2/1567 11/18639 0.181818181818182 2.16267331902303 0.235084294555393 0.528719546368964 GO:0140031 phosphorylation-dependent protein binding 2/1567 11/18639 0.181818181818182 2.16267331902303 0.235084294555393 0.528719546368964 GO:0180030 inositol phosphate kinase activity 2/1567 11/18639 0.181818181818182 2.16267331902303 0.235084294555393 0.528719546368964 GO:0001098 basal transcription machinery binding 7/1567 60/18639 0.116666666666667 1.38771537970645 0.23763940138611 0.530492418335907 GO:0001099 basal RNA polymerase II transcription machinery binding 7/1567 60/18639 0.116666666666667 1.38771537970645 0.23763940138611 0.530492418335907 GO:0004714 transmembrane receptor protein tyrosine kinase activity 7/1567 60/18639 0.116666666666667 1.38771537970645 0.23763940138611 0.530492418335907 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 7/1567 60/18639 0.116666666666667 1.38771537970645 0.23763940138611 0.530492418335907 GO:0015605 organophosphate ester transmembrane transporter activity 6/1567 50/18639 0.12 1.4273643905552 0.241282220150162 0.533383667520787 GO:0008187 poly-pyrimidine tract binding 4/1567 30/18639 0.133333333333333 1.58596043395022 0.242297501018402 0.533383667520787 GO:0015215 nucleotide transmembrane transporter activity 4/1567 30/18639 0.133333333333333 1.58596043395022 0.242297501018402 0.533383667520787 GO:0022839 monoatomic ion-gated channel activity 4/1567 30/18639 0.133333333333333 1.58596043395022 0.242297501018402 0.533383667520787 GO:0031210 phosphatidylcholine binding 4/1567 30/18639 0.133333333333333 1.58596043395022 0.242297501018402 0.533383667520787 GO:0031624 ubiquitin conjugating enzyme binding 4/1567 30/18639 0.133333333333333 1.58596043395022 0.242297501018402 0.533383667520787 GO:0070566 adenylyltransferase activity 4/1567 30/18639 0.133333333333333 1.58596043395022 0.242297501018402 0.533383667520787 GO:0004532 RNA exonuclease activity 5/1567 40/18639 0.125 1.48683790682833 0.243375728394164 0.533383667520787 GO:0015036 disulfide oxidoreductase activity 5/1567 40/18639 0.125 1.48683790682833 0.243375728394164 0.533383667520787 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 5/1567 40/18639 0.125 1.48683790682833 0.243375728394164 0.533383667520787 GO:0004722 protein serine/threonine phosphatase activity 11/1567 103/18639 0.106796116504854 1.27030811457178 0.247122850912729 0.540609369665187 GO:0016836 hydro-lyase activity 7/1567 61/18639 0.114754098360656 1.36496594725224 0.250611259301892 0.547243858948314 GO:0140789 histone phosphatase activity 14/1567 136/18639 0.102941176470588 1.2244547467998 0.252710195146236 0.550825670364118 GO:0051213 dioxygenase activity 10/1567 93/18639 0.10752688172043 1.27900034995986 0.25425677026375 0.551397130211609 GO:0005010 insulin-like growth factor receptor activity 6/1567 51/18639 0.117647058823529 1.39937685348549 0.255673749071168 0.551397130211609 GO:0001846 opsonin binding 3/1567 21/18639 0.142857142857143 1.69924332208953 0.25710440709284 0.551397130211609 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 3/1567 21/18639 0.142857142857143 1.69924332208953 0.25710440709284 0.551397130211609 GO:0005123 death receptor binding 3/1567 21/18639 0.142857142857143 1.69924332208953 0.25710440709284 0.551397130211609 GO:0051010 microtubule plus-end binding 3/1567 21/18639 0.142857142857143 1.69924332208953 0.25710440709284 0.551397130211609 GO:0061891 calcium ion sensor activity 3/1567 21/18639 0.142857142857143 1.69924332208953 0.25710440709284 0.551397130211609 GO:0070182 DNA polymerase binding 3/1567 21/18639 0.142857142857143 1.69924332208953 0.25710440709284 0.551397130211609 GO:0072542 protein phosphatase activator activity 3/1567 21/18639 0.142857142857143 1.69924332208953 0.25710440709284 0.551397130211609 GO:0001727 lipid kinase activity 5/1567 41/18639 0.121951219512195 1.4505735676374 0.259648572189871 0.554871770818568 GO:0061650 ubiquitin-like protein conjugating enzyme activity 5/1567 41/18639 0.121951219512195 1.4505735676374 0.259648572189871 0.554871770818568 GO:0016411 acylglycerol O-acyltransferase activity 4/1567 31/18639 0.129032258064516 1.53480041995183 0.261248090554497 0.555619218699846 GO:0141108 transporter regulator activity 17/1567 170/18639 0.1 1.18947032546267 0.262173009889355 0.555619218699846 GO:0016887 ATP hydrolysis activity 39/1567 417/18639 0.0935251798561151 1.11245426122408 0.264647834472583 0.555619218699846 GO:0004875 complement receptor activity 2/1567 12/18639 0.166666666666667 1.98245054243778 0.267400423320992 0.555619218699846 GO:0005095 GTPase inhibitor activity 2/1567 12/18639 0.166666666666667 1.98245054243778 0.267400423320992 0.555619218699846 GO:0005436 sodium:phosphate symporter activity 2/1567 12/18639 0.166666666666667 1.98245054243778 0.267400423320992 0.555619218699846 GO:0008603 cAMP-dependent protein kinase regulator activity 2/1567 12/18639 0.166666666666667 1.98245054243778 0.267400423320992 0.555619218699846 GO:0017166 vinculin binding 2/1567 12/18639 0.166666666666667 1.98245054243778 0.267400423320992 0.555619218699846 GO:0035197 siRNA binding 2/1567 12/18639 0.166666666666667 1.98245054243778 0.267400423320992 0.555619218699846 GO:0035251 UDP-glucosyltransferase activity 2/1567 12/18639 0.166666666666667 1.98245054243778 0.267400423320992 0.555619218699846 GO:0035497 cAMP response element binding 2/1567 12/18639 0.166666666666667 1.98245054243778 0.267400423320992 0.555619218699846 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 2/1567 12/18639 0.166666666666667 1.98245054243778 0.267400423320992 0.555619218699846 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 2/1567 12/18639 0.166666666666667 1.98245054243778 0.267400423320992 0.555619218699846 GO:0070008 serine-type exopeptidase activity 2/1567 12/18639 0.166666666666667 1.98245054243778 0.267400423320992 0.555619218699846 GO:0070679 inositol 1,4,5 trisphosphate binding 2/1567 12/18639 0.166666666666667 1.98245054243778 0.267400423320992 0.555619218699846 GO:1990247 N6-methyladenosine-containing RNA reader activity 2/1567 12/18639 0.166666666666667 1.98245054243778 0.267400423320992 0.555619218699846 GO:0030159 signaling receptor complex adaptor activity 6/1567 52/18639 0.115384615384615 1.37246576014923 0.270289621758826 0.559827663687008 GO:0015079 potassium ion transmembrane transporter activity 16/1567 160/18639 0.1 1.18947032546267 0.270358072388397 0.559827663687008 GO:0035198 miRNA binding 5/1567 42/18639 0.119047619047619 1.41603610174127 0.276166173389433 0.569889302819089 GO:0042056 chemoattractant activity 5/1567 42/18639 0.119047619047619 1.41603610174127 0.276166173389433 0.569889302819089 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 13/1567 128/18639 0.1015625 1.20805579929802 0.278962359669826 0.572239695421884 GO:0008378 galactosyltransferase activity 4/1567 32/18639 0.125 1.48683790682833 0.280466776753069 0.572239695421884 GO:0070717 poly-purine tract binding 4/1567 32/18639 0.125 1.48683790682833 0.280466776753069 0.572239695421884 GO:0120015 sterol transfer activity 4/1567 32/18639 0.125 1.48683790682833 0.280466776753069 0.572239695421884 GO:0030021 extracellular matrix structural constituent conferring compression resistance 3/1567 22/18639 0.136363636363636 1.62200498926727 0.280640450127802 0.572239695421884 GO:0031683 G-protein beta/gamma-subunit complex binding 3/1567 22/18639 0.136363636363636 1.62200498926727 0.280640450127802 0.572239695421884 GO:0140784 metal ion sensor activity 3/1567 22/18639 0.136363636363636 1.62200498926727 0.280640450127802 0.572239695421884 GO:0005003 ephrin receptor activity 6/1567 53/18639 0.113207547169811 1.34657017976906 0.285102299248771 0.5793703238541 GO:0005005 transmembrane-ephrin receptor activity 6/1567 53/18639 0.113207547169811 1.34657017976906 0.285102299248771 0.5793703238541 GO:0046906 tetrapyrrole binding 15/1567 152/18639 0.0986842105263158 1.17381940012763 0.296387200438627 0.596297730189985 GO:0016758 hexosyltransferase activity 19/1567 197/18639 0.0964467005076142 1.14720488242592 0.299324456691712 0.596297730189985 GO:0004535 poly(A)-specific ribonuclease activity 2/1567 13/18639 0.153846153846154 1.82995434686564 0.299692421095404 0.596297730189985 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 2/1567 13/18639 0.153846153846154 1.82995434686564 0.299692421095404 0.596297730189985 GO:0004993 G protein-coupled serotonin receptor activity 2/1567 13/18639 0.153846153846154 1.82995434686564 0.299692421095404 0.596297730189985 GO:0008253 5'-nucleotidase activity 2/1567 13/18639 0.153846153846154 1.82995434686564 0.299692421095404 0.596297730189985 GO:0017154 semaphorin receptor activity 2/1567 13/18639 0.153846153846154 1.82995434686564 0.299692421095404 0.596297730189985 GO:0039706 co-receptor binding 2/1567 13/18639 0.153846153846154 1.82995434686564 0.299692421095404 0.596297730189985 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 2/1567 13/18639 0.153846153846154 1.82995434686564 0.299692421095404 0.596297730189985 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 2/1567 13/18639 0.153846153846154 1.82995434686564 0.299692421095404 0.596297730189985 GO:1901338 catecholamine binding 2/1567 13/18639 0.153846153846154 1.82995434686564 0.299692421095404 0.596297730189985 GO:0140463 chromatin-protein adaptor activity 6/1567 54/18639 0.111111111111111 1.32163369495852 0.300084285259875 0.596297730189985 GO:0004721 phosphoprotein phosphatase activity 17/1567 175/18639 0.0971428571428571 1.15548545902088 0.302435406342008 0.596297730189985 GO:0000295 adenine nucleotide transmembrane transporter activity 3/1567 23/18639 0.130434782608696 1.55148303321217 0.304355127898802 0.596297730189985 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 3/1567 23/18639 0.130434782608696 1.55148303321217 0.304355127898802 0.596297730189985 GO:0005212 structural constituent of eye lens 3/1567 23/18639 0.130434782608696 1.55148303321217 0.304355127898802 0.596297730189985 GO:0016849 phosphorus-oxygen lyase activity 3/1567 23/18639 0.130434782608696 1.55148303321217 0.304355127898802 0.596297730189985 GO:0031681 G-protein beta-subunit binding 3/1567 23/18639 0.130434782608696 1.55148303321217 0.304355127898802 0.596297730189985 GO:0042171 lysophosphatidic acid acyltransferase activity 3/1567 23/18639 0.130434782608696 1.55148303321217 0.304355127898802 0.596297730189985 GO:0043274 phospholipase binding 3/1567 23/18639 0.130434782608696 1.55148303321217 0.304355127898802 0.596297730189985 GO:0071617 lysophospholipid acyltransferase activity 3/1567 23/18639 0.130434782608696 1.55148303321217 0.304355127898802 0.596297730189985 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 3/1567 23/18639 0.130434782608696 1.55148303321217 0.304355127898802 0.596297730189985 GO:0098631 cell adhesion mediator activity 8/1567 76/18639 0.105263157894737 1.25207402680281 0.306859175870913 0.600224544333821 GO:0004620 phospholipase activity 11/1567 109/18639 0.100917431192661 1.2003828972559 0.308651734195336 0.602012780667879 GO:0016248 channel inhibitor activity 5/1567 44/18639 0.113636363636364 1.35167082438939 0.3097784333495 0.602012780667879 GO:0016790 thiolester hydrolase activity 5/1567 44/18639 0.113636363636364 1.35167082438939 0.3097784333495 0.602012780667879 GO:0019205 nucleobase-containing compound kinase activity 5/1567 44/18639 0.113636363636364 1.35167082438939 0.3097784333495 0.602012780667879 GO:0015103 inorganic anion transmembrane transporter activity 16/1567 165/18639 0.096969696969697 1.15342577014562 0.312439991131549 0.606204247736656 GO:0005506 iron ion binding 15/1567 154/18639 0.0974025974025974 1.15857499233377 0.314094654246204 0.608431741531759 GO:0008374 O-acyltransferase activity 6/1567 55/18639 0.109090909090909 1.29760399141382 0.3152082658807 0.608625606628169 GO:0098632 cell-cell adhesion mediator activity 6/1567 55/18639 0.109090909090909 1.29760399141382 0.3152082658807 0.608625606628169 GO:0015035 protein-disulfide reductase activity 4/1567 34/18639 0.117647058823529 1.39937685348549 0.319465177992974 0.615855022102025 GO:0016829 lyase activity 19/1567 200/18639 0.095 1.12999680918953 0.322765899795374 0.621220906497186 GO:0004622 lysophospholipase activity 3/1567 24/18639 0.125 1.48683790682833 0.328146238881355 0.62199206384767 GO:0015295 solute:proton symporter activity 3/1567 24/18639 0.125 1.48683790682833 0.328146238881355 0.62199206384767 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 3/1567 24/18639 0.125 1.48683790682833 0.328146238881355 0.62199206384767 GO:0048027 mRNA 5'-UTR binding 3/1567 24/18639 0.125 1.48683790682833 0.328146238881355 0.62199206384767 GO:0008528 G protein-coupled peptide receptor activity 12/1567 122/18639 0.0983606557377049 1.16997081193049 0.328472146087348 0.62199206384767 GO:0030170 pyridoxal phosphate binding 6/1567 56/18639 0.107142857142857 1.27443249156714 0.330447238885389 0.62199206384767 GO:0005313 L-glutamate transmembrane transporter activity 2/1567 14/18639 0.142857142857143 1.69924332208953 0.331736065563621 0.62199206384767 GO:0005545 1-phosphatidylinositol binding 2/1567 14/18639 0.142857142857143 1.69924332208953 0.331736065563621 0.62199206384767 GO:0008195 phosphatidate phosphatase activity 2/1567 14/18639 0.142857142857143 1.69924332208953 0.331736065563621 0.62199206384767 GO:0008474 palmitoyl-(protein) hydrolase activity 2/1567 14/18639 0.142857142857143 1.69924332208953 0.331736065563621 0.62199206384767 GO:0008559 ABC-type xenobiotic transporter activity 2/1567 14/18639 0.142857142857143 1.69924332208953 0.331736065563621 0.62199206384767 GO:0016530 metallochaperone activity 2/1567 14/18639 0.142857142857143 1.69924332208953 0.331736065563621 0.62199206384767 GO:0031404 chloride ion binding 2/1567 14/18639 0.142857142857143 1.69924332208953 0.331736065563621 0.62199206384767 GO:0032036 myosin heavy chain binding 2/1567 14/18639 0.142857142857143 1.69924332208953 0.331736065563621 0.62199206384767 GO:0043176 amine binding 2/1567 14/18639 0.142857142857143 1.69924332208953 0.331736065563621 0.62199206384767 GO:0098599 palmitoyl hydrolase activity 2/1567 14/18639 0.142857142857143 1.69924332208953 0.331736065563621 0.62199206384767 GO:0003727 single-stranded RNA binding 9/1567 89/18639 0.101123595505618 1.20283516058023 0.332120011545692 0.62199206384767 GO:0019199 transmembrane receptor protein kinase activity 8/1567 78/18639 0.102564102564103 1.21996956457709 0.332488680258288 0.62199206384767 GO:0016247 channel regulator activity 16/1567 168/18639 0.0952380952380952 1.13282888139302 0.338512397646535 0.631463180294696 GO:0000175 3'-5'-RNA exonuclease activity 4/1567 35/18639 0.114285714285714 1.35939465767162 0.339128852031706 0.631463180294696 GO:0016229 steroid dehydrogenase activity 4/1567 35/18639 0.114285714285714 1.35939465767162 0.339128852031706 0.631463180294696 GO:0004180 carboxypeptidase activity 5/1567 46/18639 0.108695652173913 1.29290252767681 0.343905016369294 0.637469258114855 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 5/1567 46/18639 0.108695652173913 1.29290252767681 0.343905016369294 0.637469258114855 GO:0016835 carbon-oxygen lyase activity 8/1567 79/18639 0.10126582278481 1.20452691186093 0.345433282833906 0.637469258114855 GO:0070279 vitamin B6 binding 6/1567 57/18639 0.105263157894737 1.25207402680281 0.345774632481693 0.637469258114855 GO:0003777 microtubule motor activity 7/1567 68/18639 0.102941176470588 1.2244547467998 0.346069905321304 0.637469258114855 GO:0005548 phospholipid transporter activity 7/1567 68/18639 0.102941176470588 1.2244547467998 0.346069905321304 0.637469258114855 GO:0030145 manganese ion binding 7/1567 68/18639 0.102941176470588 1.2244547467998 0.346069905321304 0.637469258114855 GO:0005537 D-mannose binding 3/1567 25/18639 0.12 1.4273643905552 0.351919573193187 0.642333445904281 GO:0015645 fatty acid ligase activity 3/1567 25/18639 0.12 1.4273643905552 0.351919573193187 0.642333445904281 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 3/1567 25/18639 0.12 1.4273643905552 0.351919573193187 0.642333445904281 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 3/1567 25/18639 0.12 1.4273643905552 0.351919573193187 0.642333445904281 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 3/1567 25/18639 0.12 1.4273643905552 0.351919573193187 0.642333445904281 GO:0120515 fatty acid-CoA ligase activity 3/1567 25/18639 0.12 1.4273643905552 0.351919573193187 0.642333445904281 GO:0004190 aspartic-type endopeptidase activity 4/1567 36/18639 0.111111111111111 1.32163369495852 0.358829090262213 0.64362433530656 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 4/1567 36/18639 0.111111111111111 1.32163369495852 0.358829090262213 0.64362433530656 GO:0005484 SNAP receptor activity 4/1567 36/18639 0.111111111111111 1.32163369495852 0.358829090262213 0.64362433530656 GO:0045505 dynein intermediate chain binding 4/1567 36/18639 0.111111111111111 1.32163369495852 0.358829090262213 0.64362433530656 GO:0001784 phosphotyrosine residue binding 5/1567 47/18639 0.106382978723404 1.26539396325816 0.361069123619103 0.64362433530656 GO:0043495 protein-membrane adaptor activity 5/1567 47/18639 0.106382978723404 1.26539396325816 0.361069123619103 0.64362433530656 GO:0061980 regulatory RNA binding 6/1567 58/18639 0.103448275862069 1.23048654358207 0.361164413416255 0.64362433530656 GO:0004089 carbonate dehydratase activity 2/1567 15/18639 0.133333333333333 1.58596043395022 0.36334496197989 0.64362433530656 GO:0005402 carbohydrate:monoatomic cation symporter activity 2/1567 15/18639 0.133333333333333 1.58596043395022 0.36334496197989 0.64362433530656 GO:0008252 nucleotidase activity 2/1567 15/18639 0.133333333333333 1.58596043395022 0.36334496197989 0.64362433530656 GO:0015250 water channel activity 2/1567 15/18639 0.133333333333333 1.58596043395022 0.36334496197989 0.64362433530656 GO:0015556 C4-dicarboxylate transmembrane transporter activity 2/1567 15/18639 0.133333333333333 1.58596043395022 0.36334496197989 0.64362433530656 GO:0015929 hexosaminidase activity 2/1567 15/18639 0.133333333333333 1.58596043395022 0.36334496197989 0.64362433530656 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 2/1567 15/18639 0.133333333333333 1.58596043395022 0.36334496197989 0.64362433530656 GO:0031005 filamin binding 2/1567 15/18639 0.133333333333333 1.58596043395022 0.36334496197989 0.64362433530656 GO:0031386 protein tag activity 2/1567 15/18639 0.133333333333333 1.58596043395022 0.36334496197989 0.64362433530656 GO:0033130 acetylcholine receptor binding 2/1567 15/18639 0.133333333333333 1.58596043395022 0.36334496197989 0.64362433530656 GO:0061578 K63-linked deubiquitinase activity 2/1567 15/18639 0.133333333333333 1.58596043395022 0.36334496197989 0.64362433530656 GO:0140161 monocarboxylate:sodium symporter activity 2/1567 15/18639 0.133333333333333 1.58596043395022 0.36334496197989 0.64362433530656 GO:0141047 molecular tag activity 2/1567 15/18639 0.133333333333333 1.58596043395022 0.36334496197989 0.64362433530656 GO:0043178 alcohol binding 9/1567 92/18639 0.0978260869565217 1.16361227490913 0.368578484056912 0.651146197558291 GO:0099106 ion channel regulator activity 15/1567 160/18639 0.09375 1.11512843012125 0.368675615603362 0.651146197558291 GO:0017124 SH3 domain binding 11/1567 115/18639 0.0956521739130435 1.13775422435559 0.373418823385085 0.658555076190143 GO:0004529 DNA exonuclease activity 3/1567 26/18639 0.115384615384615 1.37246576014923 0.375588956570864 0.659309056194937 GO:0015216 purine nucleotide transmembrane transporter activity 3/1567 26/18639 0.115384615384615 1.37246576014923 0.375588956570864 0.659309056194937 GO:0070412 R-SMAD binding 3/1567 26/18639 0.115384615384615 1.37246576014923 0.375588956570864 0.659309056194937 GO:0015459 potassium channel regulator activity 6/1567 59/18639 0.101694915254237 1.20963083945356 0.376591184471046 0.659309056194937 GO:0045309 protein phosphorylated amino acid binding 6/1567 59/18639 0.101694915254237 1.20963083945356 0.376591184471046 0.659309056194937 GO:0030551 cyclic nucleotide binding 4/1567 37/18639 0.108108108108108 1.28591386536505 0.378514599018738 0.66171183904149 GO:0042826 histone deacetylase binding 12/1567 127/18639 0.094488188976378 1.1239089689411 0.380264234516085 0.663804281473573 GO:0046982 protein heterodimerization activity 33/1567 369/18639 0.0894308943089431 1.06375394960076 0.380882661367826 0.663918833530854 GO:0001653 peptide receptor activity 12/1567 128/18639 0.09375 1.11512843012125 0.390743738810526 0.669400120087443 GO:0031490 chromatin DNA binding 12/1567 128/18639 0.09375 1.11512843012125 0.390743738810526 0.669400120087443 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 6/1567 60/18639 0.1 1.18947032546267 0.392030271480484 0.669400120087443 GO:0004708 MAP kinase kinase activity 2/1567 16/18639 0.125 1.48683790682833 0.394365774063671 0.669400120087443 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/1567 16/18639 0.125 1.48683790682833 0.394365774063671 0.669400120087443 GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity 2/1567 16/18639 0.125 1.48683790682833 0.394365774063671 0.669400120087443 GO:0030275 LRR domain binding 2/1567 16/18639 0.125 1.48683790682833 0.394365774063671 0.669400120087443 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/1567 16/18639 0.125 1.48683790682833 0.394365774063671 0.669400120087443 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 2/1567 16/18639 0.125 1.48683790682833 0.394365774063671 0.669400120087443 GO:0019208 phosphatase regulator activity 11/1567 117/18639 0.094017094017094 1.11830543419567 0.395388315708171 0.669400120087443 GO:0005004 GPI-linked ephrin receptor activity 5/1567 49/18639 0.102040816326531 1.21374523006395 0.395425445503123 0.669400120087443 GO:0005008 hepatocyte growth factor receptor activity 5/1567 49/18639 0.102040816326531 1.21374523006395 0.395425445503123 0.669400120087443 GO:0005009 insulin receptor activity 5/1567 49/18639 0.102040816326531 1.21374523006395 0.395425445503123 0.669400120087443 GO:0005011 macrophage colony-stimulating factor receptor activity 5/1567 49/18639 0.102040816326531 1.21374523006395 0.395425445503123 0.669400120087443 GO:0005018 platelet-derived growth factor alpha-receptor activity 5/1567 49/18639 0.102040816326531 1.21374523006395 0.395425445503123 0.669400120087443 GO:0005020 stem cell factor receptor activity 5/1567 49/18639 0.102040816326531 1.21374523006395 0.395425445503123 0.669400120087443 GO:0008288 boss receptor activity 5/1567 49/18639 0.102040816326531 1.21374523006395 0.395425445503123 0.669400120087443 GO:0036332 placental growth factor receptor activity 5/1567 49/18639 0.102040816326531 1.21374523006395 0.395425445503123 0.669400120087443 GO:0038062 protein tyrosine kinase collagen receptor activity 5/1567 49/18639 0.102040816326531 1.21374523006395 0.395425445503123 0.669400120087443 GO:0060175 brain-derived neurotrophic factor receptor activity 5/1567 49/18639 0.102040816326531 1.21374523006395 0.395425445503123 0.669400120087443 GO:0000146 microfilament motor activity 4/1567 38/18639 0.105263157894737 1.25207402680281 0.398137079835143 0.669400120087443 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 4/1567 38/18639 0.105263157894737 1.25207402680281 0.398137079835143 0.669400120087443 GO:0004364 glutathione transferase activity 3/1567 27/18639 0.111111111111111 1.32163369495852 0.399076174839808 0.669400120087443 GO:0005385 zinc ion transmembrane transporter activity 3/1567 27/18639 0.111111111111111 1.32163369495852 0.399076174839808 0.669400120087443 GO:0016405 CoA-ligase activity 3/1567 27/18639 0.111111111111111 1.32163369495852 0.399076174839808 0.669400120087443 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 3/1567 27/18639 0.111111111111111 1.32163369495852 0.399076174839808 0.669400120087443 GO:0035255 ionotropic glutamate receptor binding 3/1567 27/18639 0.111111111111111 1.32163369495852 0.399076174839808 0.669400120087443 GO:0019888 protein phosphatase regulator activity 10/1567 107/18639 0.0934579439252336 1.11165450977819 0.411865942890421 0.687205987685646 GO:0005006 epidermal growth factor receptor activity 5/1567 50/18639 0.1 1.18947032546267 0.41255247054234 0.687205987685646 GO:0005007 fibroblast growth factor receptor activity 5/1567 50/18639 0.1 1.18947032546267 0.41255247054234 0.687205987685646 GO:0005017 platelet-derived growth factor receptor activity 5/1567 50/18639 0.1 1.18947032546267 0.41255247054234 0.687205987685646 GO:0005019 platelet-derived growth factor beta-receptor activity 5/1567 50/18639 0.1 1.18947032546267 0.41255247054234 0.687205987685646 GO:0020037 heme binding 13/1567 142/18639 0.0915492957746479 1.08895170640948 0.416495266216894 0.692069966287058 GO:0004521 RNA endonuclease activity 7/1567 73/18639 0.0958904109589041 1.14058798332037 0.416624967215273 0.692069966287058 GO:0141052 histone H3 demethylase activity 3/1567 28/18639 0.107142857142857 1.27443249156714 0.42231080329526 0.693923075312687 GO:0015399 primary active transmembrane transporter activity 15/1567 166/18639 0.0903614457831325 1.0748225832494 0.424534847184261 0.693923075312687 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 2/1567 17/18639 0.117647058823529 1.39937685348549 0.424673988638489 0.693923075312687 GO:0005092 GDP-dissociation inhibitor activity 2/1567 17/18639 0.117647058823529 1.39937685348549 0.424673988638489 0.693923075312687 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/1567 17/18639 0.117647058823529 1.39937685348549 0.424673988638489 0.693923075312687 GO:0016018 cyclosporin A binding 2/1567 17/18639 0.117647058823529 1.39937685348549 0.424673988638489 0.693923075312687 GO:0017110 nucleoside diphosphate phosphatase activity 2/1567 17/18639 0.117647058823529 1.39937685348549 0.424673988638489 0.693923075312687 GO:0032183 SUMO binding 2/1567 17/18639 0.117647058823529 1.39937685348549 0.424673988638489 0.693923075312687 GO:0045125 bioactive lipid receptor activity 2/1567 17/18639 0.117647058823529 1.39937685348549 0.424673988638489 0.693923075312687 GO:0045236 CXCR chemokine receptor binding 2/1567 17/18639 0.117647058823529 1.39937685348549 0.424673988638489 0.693923075312687 GO:0048038 quinone binding 2/1567 17/18639 0.117647058823529 1.39937685348549 0.424673988638489 0.693923075312687 GO:1990226 histone methyltransferase binding 2/1567 17/18639 0.117647058823529 1.39937685348549 0.424673988638489 0.693923075312687 GO:0005021 vascular endothelial growth factor receptor activity 5/1567 51/18639 0.0980392156862745 1.16614737790458 0.429604505484859 0.700074641909519 GO:0005030 neurotrophin receptor activity 5/1567 51/18639 0.0980392156862745 1.16614737790458 0.429604505484859 0.700074641909519 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 8/1567 86/18639 0.0930232558139535 1.1064840236862 0.437023299441778 0.711199163454709 GO:0016853 isomerase activity 16/1567 180/18639 0.0888888888888889 1.05730695596682 0.446079429727661 0.724954526526279 GO:0008081 phosphoric diester hydrolase activity 8/1567 87/18639 0.0919540229885057 1.0937658165174 0.450070488069492 0.725343563606842 GO:0000900 mRNA regulatory element binding translation repressor activity 2/1567 18/18639 0.111111111111111 1.32163369495852 0.454170158061903 0.725343563606842 GO:0004706 JUN kinase kinase kinase activity 2/1567 18/18639 0.111111111111111 1.32163369495852 0.454170158061903 0.725343563606842 GO:0005372 water transmembrane transporter activity 2/1567 18/18639 0.111111111111111 1.32163369495852 0.454170158061903 0.725343563606842 GO:0008409 5'-3' exonuclease activity 2/1567 18/18639 0.111111111111111 1.32163369495852 0.454170158061903 0.725343563606842 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 2/1567 18/18639 0.111111111111111 1.32163369495852 0.454170158061903 0.725343563606842 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 2/1567 18/18639 0.111111111111111 1.32163369495852 0.454170158061903 0.725343563606842 GO:0017128 phospholipid scramblase activity 2/1567 18/18639 0.111111111111111 1.32163369495852 0.454170158061903 0.725343563606842 GO:0031690 adrenergic receptor binding 2/1567 18/18639 0.111111111111111 1.32163369495852 0.454170158061903 0.725343563606842 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 2/1567 18/18639 0.111111111111111 1.32163369495852 0.454170158061903 0.725343563606842 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 2/1567 18/18639 0.111111111111111 1.32163369495852 0.454170158061903 0.725343563606842 GO:0099602 neurotransmitter receptor regulator activity 2/1567 18/18639 0.111111111111111 1.32163369495852 0.454170158061903 0.725343563606842 GO:1901611 phosphatidylglycerol binding 2/1567 18/18639 0.111111111111111 1.32163369495852 0.454170158061903 0.725343563606842 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 4/1567 41/18639 0.0975609756097561 1.16045885410992 0.456190061063486 0.725674520976485 GO:0008227 G protein-coupled amine receptor activity 4/1567 41/18639 0.0975609756097561 1.16045885410992 0.456190061063486 0.725674520976485 GO:0017080 sodium channel regulator activity 4/1567 41/18639 0.0975609756097561 1.16045885410992 0.456190061063486 0.725674520976485 GO:1902936 phosphatidylinositol bisphosphate binding 10/1567 111/18639 0.0900900900900901 1.0715948878042 0.458202237764436 0.727911226924719 GO:0008017 microtubule binding 24/1567 276/18639 0.0869565217391304 1.03432202214145 0.462500853646977 0.733769518137409 GO:0016860 intramolecular oxidoreductase activity 5/1567 53/18639 0.0943396226415094 1.12214181647421 0.463370668008299 0.734179646804705 GO:0032452 histone demethylase activity 3/1567 30/18639 0.1 1.18947032546267 0.467778012960339 0.740186289282433 GO:0015485 cholesterol binding 5/1567 54/18639 0.0925925925925926 1.10136141246543 0.480032543798954 0.755951317752149 GO:0003756 protein disulfide isomerase activity 2/1567 19/18639 0.105263157894737 1.25207402680281 0.482776570121481 0.755951317752149 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 2/1567 19/18639 0.105263157894737 1.25207402680281 0.482776570121481 0.755951317752149 GO:0042834 peptidoglycan binding 2/1567 19/18639 0.105263157894737 1.25207402680281 0.482776570121481 0.755951317752149 GO:0046527 glucosyltransferase activity 2/1567 19/18639 0.105263157894737 1.25207402680281 0.482776570121481 0.755951317752149 GO:0046624 sphingolipid transporter activity 2/1567 19/18639 0.105263157894737 1.25207402680281 0.482776570121481 0.755951317752149 GO:0099589 serotonin receptor activity 2/1567 19/18639 0.105263157894737 1.25207402680281 0.482776570121481 0.755951317752149 GO:0140036 ubiquitin-modified protein reader activity 2/1567 19/18639 0.105263157894737 1.25207402680281 0.482776570121481 0.755951317752149 GO:0005452 solute:inorganic anion antiporter activity 3/1567 31/18639 0.0967741935483871 1.15110031496387 0.489906218932392 0.763980577478342 GO:0016878 acid-thiol ligase activity 3/1567 31/18639 0.0967741935483871 1.15110031496387 0.489906218932392 0.763980577478342 GO:0140457 protein demethylase activity 3/1567 31/18639 0.0967741935483871 1.15110031496387 0.489906218932392 0.763980577478342 GO:0008238 exopeptidase activity 9/1567 102/18639 0.0882352941176471 1.04953264011412 0.490857944186178 0.763980577478342 GO:1901981 phosphatidylinositol phosphate binding 16/1567 185/18639 0.0864864864864865 1.02873109229204 0.491084934066012 0.763980577478342 GO:0004518 nuclease activity 18/1567 209/18639 0.0861244019138756 1.02442420374775 0.493425449639734 0.764294639117576 GO:0005245 voltage-gated calcium channel activity 4/1567 43/18639 0.0930232558139535 1.1064840236862 0.493832339679633 0.764294639117576 GO:0008200 ion channel inhibitor activity 4/1567 43/18639 0.0930232558139535 1.1064840236862 0.493832339679633 0.764294639117576 GO:0008375 acetylglucosaminyltransferase activity 4/1567 43/18639 0.0930232558139535 1.1064840236862 0.493832339679633 0.764294639117576 GO:0016500 protein-hormone receptor activity 6/1567 67/18639 0.0895522388059701 1.06519730638448 0.498558905981444 0.770616790326531 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 8/1567 91/18639 0.0879120879120879 1.04568819820894 0.501627285068543 0.774362942631517 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 41/1567 484/18639 0.0847107438016529 1.00760915999937 0.503874680962249 0.776833750751812 GO:0001972 retinoic acid binding 2/1567 20/18639 0.1 1.18947032546267 0.51043430014847 0.779693418929127 GO:0005326 neurotransmitter transmembrane transporter activity 2/1567 20/18639 0.1 1.18947032546267 0.51043430014847 0.779693418929127 GO:0015095 magnesium ion transmembrane transporter activity 2/1567 20/18639 0.1 1.18947032546267 0.51043430014847 0.779693418929127 GO:0015464 acetylcholine receptor activity 2/1567 20/18639 0.1 1.18947032546267 0.51043430014847 0.779693418929127 GO:0016505 peptidase activator activity involved in apoptotic process 2/1567 20/18639 0.1 1.18947032546267 0.51043430014847 0.779693418929127 GO:0030742 GTP-dependent protein binding 2/1567 20/18639 0.1 1.18947032546267 0.51043430014847 0.779693418929127 GO:0015106 bicarbonate transmembrane transporter activity 3/1567 32/18639 0.09375 1.11512843012125 0.511572368123358 0.779693418929127 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 3/1567 32/18639 0.09375 1.11512843012125 0.511572368123358 0.779693418929127 GO:0043425 bHLH transcription factor binding 3/1567 32/18639 0.09375 1.11512843012125 0.511572368123358 0.779693418929127 GO:0030020 extracellular matrix structural constituent conferring tensile strength 4/1567 44/18639 0.0909090909090909 1.08133665951152 0.512237730312646 0.779718015342824 GO:0048306 calcium-dependent protein binding 7/1567 80/18639 0.0875 1.04078653477983 0.513814823463274 0.780875623186061 GO:0052689 carboxylic ester hydrolase activity 8/1567 92/18639 0.0869565217391304 1.03432202214145 0.514298599450603 0.780875623186061 GO:0002039 p53 binding 6/1567 69/18639 0.0869565217391304 1.03432202214145 0.527905240016193 0.800522971287181 GO:0015932 nucleobase-containing compound transmembrane transporter activity 5/1567 57/18639 0.087719298245614 1.04339502233567 0.528855880449698 0.800953231298975 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 3/1567 33/18639 0.0909090909090909 1.08133665951152 0.5327403833527 0.805820151645583 GO:0008373 sialyltransferase activity 2/1567 21/18639 0.0952380952380952 1.13282888139302 0.537100604680642 0.806322282776813 GO:0009975 cyclase activity 2/1567 21/18639 0.0952380952380952 1.13282888139302 0.537100604680642 0.806322282776813 GO:0010314 phosphatidylinositol-5-phosphate binding 2/1567 21/18639 0.0952380952380952 1.13282888139302 0.537100604680642 0.806322282776813 GO:0019200 carbohydrate kinase activity 2/1567 21/18639 0.0952380952380952 1.13282888139302 0.537100604680642 0.806322282776813 GO:0035613 RNA stem-loop binding 2/1567 21/18639 0.0952380952380952 1.13282888139302 0.537100604680642 0.806322282776813 GO:0051428 peptide hormone receptor binding 2/1567 21/18639 0.0952380952380952 1.13282888139302 0.537100604680642 0.806322282776813 GO:0004497 monooxygenase activity 9/1567 106/18639 0.0849056603773585 1.00992763482679 0.538313187364347 0.807133755336556 GO:0001216 DNA-binding transcription activator activity 41/1567 491/18639 0.0835030549898167 0.993244059958643 0.542577283838998 0.812512865200295 GO:0005262 calcium channel activity 11/1567 131/18639 0.083969465648855 0.998791876342698 0.547445966357037 0.818717990186427 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 4/1567 46/18639 0.0869565217391304 1.03432202214145 0.548084316494494 0.818717990186427 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 3/1567 34/18639 0.0882352941176471 1.04953264011412 0.553379919355254 0.823555493365131 GO:0019825 oxygen binding 3/1567 34/18639 0.0882352941176471 1.04953264011412 0.553379919355254 0.823555493365131 GO:0030332 cyclin binding 3/1567 34/18639 0.0882352941176471 1.04953264011412 0.553379919355254 0.823555493365131 GO:0005179 hormone activity 11/1567 132/18639 0.0833333333333333 0.99122527121889 0.557867673242603 0.829206776688572 GO:0031593 polyubiquitin modification-dependent protein binding 5/1567 59/18639 0.0847457627118644 1.00802569954463 0.560239223290092 0.83029323192045 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 2/1567 22/18639 0.0909090909090909 1.08133665951152 0.562746620135926 0.83029323192045 GO:0016881 acid-amino acid ligase activity 2/1567 22/18639 0.0909090909090909 1.08133665951152 0.562746620135926 0.83029323192045 GO:0050321 tau-protein kinase activity 2/1567 22/18639 0.0909090909090909 1.08133665951152 0.562746620135926 0.83029323192045 GO:0140035 ubiquitin-like protein reader activity 2/1567 22/18639 0.0909090909090909 1.08133665951152 0.562746620135926 0.83029323192045 GO:0140517 protein-RNA adaptor activity 2/1567 22/18639 0.0909090909090909 1.08133665951152 0.562746620135926 0.83029323192045 GO:0004527 exonuclease activity 7/1567 84/18639 0.0833333333333333 0.99122527121889 0.566746656802197 0.832789109229818 GO:0005154 epidermal growth factor receptor binding 3/1567 35/18639 0.0857142857142857 1.01954599325371 0.573465956916837 0.832789109229818 GO:0043015 gamma-tubulin binding 3/1567 35/18639 0.0857142857142857 1.01954599325371 0.573465956916837 0.832789109229818 GO:0140566 histone reader activity 3/1567 35/18639 0.0857142857142857 1.01954599325371 0.573465956916837 0.832789109229818 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 4/1567 48/18639 0.0833333333333333 0.99122527121889 0.582501748224963 0.832789109229818 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/1567 10/18639 0.1 1.18947032546267 0.584547226545159 0.832789109229818 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/1567 10/18639 0.1 1.18947032546267 0.584547226545159 0.832789109229818 GO:0003796 lysozyme activity 1/1567 10/18639 0.1 1.18947032546267 0.584547226545159 0.832789109229818 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/1567 10/18639 0.1 1.18947032546267 0.584547226545159 0.832789109229818 GO:0005337 nucleoside transmembrane transporter activity 1/1567 10/18639 0.1 1.18947032546267 0.584547226545159 0.832789109229818 GO:0005522 profilin binding 1/1567 10/18639 0.1 1.18947032546267 0.584547226545159 0.832789109229818 GO:0008140 cAMP response element binding protein binding 1/1567 10/18639 0.1 1.18947032546267 0.584547226545159 0.832789109229818 GO:0008401 retinoic acid 4-hydroxylase activity 1/1567 10/18639 0.1 1.18947032546267 0.584547226545159 0.832789109229818 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/1567 10/18639 0.1 1.18947032546267 0.584547226545159 0.832789109229818 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/1567 10/18639 0.1 1.18947032546267 0.584547226545159 0.832789109229818 GO:0016783 sulfurtransferase activity 1/1567 10/18639 0.1 1.18947032546267 0.584547226545159 0.832789109229818 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/1567 10/18639 0.1 1.18947032546267 0.584547226545159 0.832789109229818 GO:0031434 mitogen-activated protein kinase kinase binding 1/1567 10/18639 0.1 1.18947032546267 0.584547226545159 0.832789109229818 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/1567 10/18639 0.1 1.18947032546267 0.584547226545159 0.832789109229818 GO:0032052 bile acid binding 1/1567 10/18639 0.1 1.18947032546267 0.584547226545159 0.832789109229818 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/1567 10/18639 0.1 1.18947032546267 0.584547226545159 0.832789109229818 GO:0043121 neurotrophin binding 1/1567 10/18639 0.1 1.18947032546267 0.584547226545159 0.832789109229818 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/1567 10/18639 0.1 1.18947032546267 0.584547226545159 0.832789109229818 GO:0043295 glutathione binding 1/1567 10/18639 0.1 1.18947032546267 0.584547226545159 0.832789109229818 GO:0045322 unmethylated CpG binding 1/1567 10/18639 0.1 1.18947032546267 0.584547226545159 0.832789109229818 GO:0050815 phosphoserine residue binding 1/1567 10/18639 0.1 1.18947032546267 0.584547226545159 0.832789109229818 GO:0051378 serotonin binding 1/1567 10/18639 0.1 1.18947032546267 0.584547226545159 0.832789109229818 GO:0051880 G-quadruplex DNA binding 1/1567 10/18639 0.1 1.18947032546267 0.584547226545159 0.832789109229818 GO:1990763 arrestin family protein binding 1/1567 10/18639 0.1 1.18947032546267 0.584547226545159 0.832789109229818 GO:0099186 structural constituent of postsynapse 2/1567 23/18639 0.0869565217391304 1.03432202214145 0.587355333682319 0.835798288806238 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 5/1567 61/18639 0.0819672131147541 0.974975676608744 0.590537477083668 0.839331964470397 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 3/1567 36/18639 0.0833333333333333 0.99122527121889 0.592978399339984 0.83981964340486 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 3/1567 36/18639 0.0833333333333333 0.99122527121889 0.592978399339984 0.83981964340486 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 3/1567 36/18639 0.0833333333333333 0.99122527121889 0.592978399339984 0.83981964340486 GO:0016779 nucleotidyltransferase activity 11/1567 136/18639 0.0808823529411765 0.962071586771275 0.59856274774424 0.846730106055161 GO:0005267 potassium channel activity 10/1567 124/18639 0.0806451612903226 0.959250262469893 0.602025550182652 0.848359996821787 GO:0008509 monoatomic anion transmembrane transporter activity 12/1567 149/18639 0.0805369127516778 0.957962678224967 0.605102908589333 0.848359996821787 GO:0042625 ATPase-coupled ion transmembrane transporter activity 2/1567 24/18639 0.0833333333333333 0.99122527121889 0.610919796846042 0.848359996821787 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 2/1567 24/18639 0.0833333333333333 0.99122527121889 0.610919796846042 0.848359996821787 GO:0046961 proton-transporting ATPase activity, rotational mechanism 2/1567 24/18639 0.0833333333333333 0.99122527121889 0.610919796846042 0.848359996821787 GO:0050699 WW domain binding 2/1567 24/18639 0.0833333333333333 0.99122527121889 0.610919796846042 0.848359996821787 GO:0070300 phosphatidic acid binding 2/1567 24/18639 0.0833333333333333 0.99122527121889 0.610919796846042 0.848359996821787 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/1567 11/18639 0.0909090909090909 1.08133665951152 0.619493519744136 0.848359996821787 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/1567 11/18639 0.0909090909090909 1.08133665951152 0.619493519744136 0.848359996821787 GO:0001851 complement component C3b binding 1/1567 11/18639 0.0909090909090909 1.08133665951152 0.619493519744136 0.848359996821787 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/1567 11/18639 0.0909090909090909 1.08133665951152 0.619493519744136 0.848359996821787 GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity 1/1567 11/18639 0.0909090909090909 1.08133665951152 0.619493519744136 0.848359996821787 GO:0008046 axon guidance receptor activity 1/1567 11/18639 0.0909090909090909 1.08133665951152 0.619493519744136 0.848359996821787 GO:0008526 phosphatidylinositol transfer activity 1/1567 11/18639 0.0909090909090909 1.08133665951152 0.619493519744136 0.848359996821787 GO:0015217 ADP transmembrane transporter activity 1/1567 11/18639 0.0909090909090909 1.08133665951152 0.619493519744136 0.848359996821787 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/1567 11/18639 0.0909090909090909 1.08133665951152 0.619493519744136 0.848359996821787 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/1567 11/18639 0.0909090909090909 1.08133665951152 0.619493519744136 0.848359996821787 GO:0019864 IgG binding 1/1567 11/18639 0.0909090909090909 1.08133665951152 0.619493519744136 0.848359996821787 GO:0032050 clathrin heavy chain binding 1/1567 11/18639 0.0909090909090909 1.08133665951152 0.619493519744136 0.848359996821787 GO:0032794 GTPase activating protein binding 1/1567 11/18639 0.0909090909090909 1.08133665951152 0.619493519744136 0.848359996821787 GO:0034056 estrogen response element binding 1/1567 11/18639 0.0909090909090909 1.08133665951152 0.619493519744136 0.848359996821787 GO:0034511 U3 snoRNA binding 1/1567 11/18639 0.0909090909090909 1.08133665951152 0.619493519744136 0.848359996821787 GO:0035252 UDP-xylosyltransferase activity 1/1567 11/18639 0.0909090909090909 1.08133665951152 0.619493519744136 0.848359996821787 GO:0042285 xylosyltransferase activity 1/1567 11/18639 0.0909090909090909 1.08133665951152 0.619493519744136 0.848359996821787 GO:0043855 cyclic nucleotide-activated monoatomic ion channel activity 1/1567 11/18639 0.0909090909090909 1.08133665951152 0.619493519744136 0.848359996821787 GO:0048185 activin binding 1/1567 11/18639 0.0909090909090909 1.08133665951152 0.619493519744136 0.848359996821787 GO:0050998 nitric-oxide synthase binding 1/1567 11/18639 0.0909090909090909 1.08133665951152 0.619493519744136 0.848359996821787 GO:1900750 oligopeptide binding 1/1567 11/18639 0.0909090909090909 1.08133665951152 0.619493519744136 0.848359996821787 GO:0017022 myosin binding 6/1567 76/18639 0.0789473684210526 0.939055520102106 0.624233484853474 0.853877466183397 GO:0016597 amino acid binding 4/1567 51/18639 0.0784313725490196 0.932917902323661 0.631163499964888 0.857681294323435 GO:0016830 carbon-carbon lyase activity 4/1567 51/18639 0.0784313725490196 0.932917902323661 0.631163499964888 0.857681294323435 GO:0000030 mannosyltransferase activity 2/1567 25/18639 0.08 0.951576260370134 0.633441555424552 0.857681294323435 GO:0001848 complement binding 2/1567 25/18639 0.08 0.951576260370134 0.633441555424552 0.857681294323435 GO:0004709 MAP kinase kinase kinase activity 2/1567 25/18639 0.08 0.951576260370134 0.633441555424552 0.857681294323435 GO:0005251 delayed rectifier potassium channel activity 2/1567 25/18639 0.08 0.951576260370134 0.633441555424552 0.857681294323435 GO:0008139 nuclear localization sequence binding 2/1567 25/18639 0.08 0.951576260370134 0.633441555424552 0.857681294323435 GO:0019706 protein-cysteine S-palmitoyltransferase activity 2/1567 25/18639 0.08 0.951576260370134 0.633441555424552 0.857681294323435 GO:0019707 protein-cysteine S-acyltransferase activity 2/1567 25/18639 0.08 0.951576260370134 0.633441555424552 0.857681294323435 GO:0120013 lipid transfer activity 5/1567 65/18639 0.0769230769230769 0.914977173432821 0.647494136988414 0.860579929613596 GO:0160215 deacylase activity 5/1567 65/18639 0.0769230769230769 0.914977173432821 0.647494136988414 0.860579929613596 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 3/1567 39/18639 0.0769230769230769 0.914977173432821 0.64793877459321 0.860579929613596 GO:0004126 cytidine deaminase activity 1/1567 12/18639 0.0833333333333333 0.99122527121889 0.651501983055331 0.860579929613596 GO:0005025 transforming growth factor beta receptor activity, type I 1/1567 12/18639 0.0833333333333333 0.99122527121889 0.651501983055331 0.860579929613596 GO:0005026 transforming growth factor beta receptor activity, type II 1/1567 12/18639 0.0833333333333333 0.99122527121889 0.651501983055331 0.860579929613596 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/1567 12/18639 0.0833333333333333 0.99122527121889 0.651501983055331 0.860579929613596 GO:0008504 monoamine transmembrane transporter activity 1/1567 12/18639 0.0833333333333333 0.99122527121889 0.651501983055331 0.860579929613596 GO:0010853 cyclase activator activity 1/1567 12/18639 0.0833333333333333 0.99122527121889 0.651501983055331 0.860579929613596 GO:0016361 activin receptor activity, type I 1/1567 12/18639 0.0833333333333333 0.99122527121889 0.651501983055331 0.860579929613596 GO:0016362 activin receptor activity, type II 1/1567 12/18639 0.0833333333333333 0.99122527121889 0.651501983055331 0.860579929613596 GO:0016801 hydrolase activity, acting on ether bonds 1/1567 12/18639 0.0833333333333333 0.99122527121889 0.651501983055331 0.860579929613596 GO:0016803 ether hydrolase activity 1/1567 12/18639 0.0833333333333333 0.99122527121889 0.651501983055331 0.860579929613596 GO:0017002 activin receptor activity 1/1567 12/18639 0.0833333333333333 0.99122527121889 0.651501983055331 0.860579929613596 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/1567 12/18639 0.0833333333333333 0.99122527121889 0.651501983055331 0.860579929613596 GO:0045295 gamma-catenin binding 1/1567 12/18639 0.0833333333333333 0.99122527121889 0.651501983055331 0.860579929613596 GO:0070410 co-SMAD binding 1/1567 12/18639 0.0833333333333333 0.99122527121889 0.651501983055331 0.860579929613596 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/1567 12/18639 0.0833333333333333 0.99122527121889 0.651501983055331 0.860579929613596 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/1567 12/18639 0.0833333333333333 0.99122527121889 0.651501983055331 0.860579929613596 GO:1990459 transferrin receptor binding 1/1567 12/18639 0.0833333333333333 0.99122527121889 0.651501983055331 0.860579929613596 GO:1990817 poly(A) RNA polymerase activity 1/1567 12/18639 0.0833333333333333 0.99122527121889 0.651501983055331 0.860579929613596 GO:0004435 phosphatidylinositol phospholipase C activity 2/1567 26/18639 0.0769230769230769 0.914977173432821 0.654929271995693 0.860579929613596 GO:0005112 Notch binding 2/1567 26/18639 0.0769230769230769 0.914977173432821 0.654929271995693 0.860579929613596 GO:0030507 spectrin binding 2/1567 26/18639 0.0769230769230769 0.914977173432821 0.654929271995693 0.860579929613596 GO:0052742 phosphatidylinositol kinase activity 2/1567 26/18639 0.0769230769230769 0.914977173432821 0.654929271995693 0.860579929613596 GO:0070006 metalloaminopeptidase activity 2/1567 26/18639 0.0769230769230769 0.914977173432821 0.654929271995693 0.860579929613596 GO:0097602 cullin family protein binding 2/1567 26/18639 0.0769230769230769 0.914977173432821 0.654929271995693 0.860579929613596 GO:0008235 metalloexopeptidase activity 5/1567 66/18639 0.0757575757575758 0.901113882926263 0.660923978712164 0.867317287483238 GO:0004864 protein phosphatase inhibitor activity 4/1567 53/18639 0.0754716981132075 0.897713453179372 0.661500945324435 0.867317287483238 GO:0004177 aminopeptidase activity 3/1567 40/18639 0.075 0.892102744097001 0.665040679425536 0.869111921643166 GO:0030331 nuclear estrogen receptor binding 3/1567 40/18639 0.075 0.892102744097001 0.665040679425536 0.869111921643166 GO:0032451 demethylase activity 3/1567 40/18639 0.075 0.892102744097001 0.665040679425536 0.869111921643166 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 5/1567 67/18639 0.0746268656716418 0.887664421987065 0.674017936190447 0.872618541846624 GO:0008320 protein transmembrane transporter activity 2/1567 27/18639 0.0740740740740741 0.881089129972346 0.675397519768163 0.872618541846624 GO:0015252 proton channel activity 2/1567 27/18639 0.0740740740740741 0.881089129972346 0.675397519768163 0.872618541846624 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 2/1567 27/18639 0.0740740740740741 0.881089129972346 0.675397519768163 0.872618541846624 GO:0050661 NADP binding 4/1567 54/18639 0.0740740740740741 0.881089129972346 0.676018417446473 0.872618541846624 GO:0000149 SNARE binding 8/1567 106/18639 0.0754716981132075 0.897713453179372 0.676359691772702 0.872618541846624 GO:0005035 death receptor activity 1/1567 13/18639 0.0769230769230769 0.914977173432821 0.680819446551992 0.872618541846624 GO:0009982 pseudouridine synthase activity 1/1567 13/18639 0.0769230769230769 0.914977173432821 0.680819446551992 0.872618541846624 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/1567 13/18639 0.0769230769230769 0.914977173432821 0.680819446551992 0.872618541846624 GO:0035325 Toll-like receptor binding 1/1567 13/18639 0.0769230769230769 0.914977173432821 0.680819446551992 0.872618541846624 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/1567 13/18639 0.0769230769230769 0.914977173432821 0.680819446551992 0.872618541846624 GO:0045159 myosin II binding 1/1567 13/18639 0.0769230769230769 0.914977173432821 0.680819446551992 0.872618541846624 GO:0051011 microtubule minus-end binding 1/1567 13/18639 0.0769230769230769 0.914977173432821 0.680819446551992 0.872618541846624 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/1567 13/18639 0.0769230769230769 0.914977173432821 0.680819446551992 0.872618541846624 GO:0061459 L-arginine transmembrane transporter activity 1/1567 13/18639 0.0769230769230769 0.914977173432821 0.680819446551992 0.872618541846624 GO:0070123 transforming growth factor beta receptor activity, type III 1/1567 13/18639 0.0769230769230769 0.914977173432821 0.680819446551992 0.872618541846624 GO:0089720 caspase binding 1/1567 13/18639 0.0769230769230769 0.914977173432821 0.680819446551992 0.872618541846624 GO:0140852 histone ubiquitin ligase activity 1/1567 13/18639 0.0769230769230769 0.914977173432821 0.680819446551992 0.872618541846624 GO:0016877 ligase activity, forming carbon-sulfur bonds 3/1567 41/18639 0.0731707317073171 0.87034414058244 0.68152888613833 0.872618541846624 GO:0035091 phosphatidylinositol binding 22/1567 284/18639 0.0774647887323944 0.921420674654179 0.68800627286444 0.879611989417138 GO:0042393 histone binding 19/1567 247/18639 0.0769230769230769 0.914977173432821 0.691389277889406 0.879611989417138 GO:0008527 taste receptor activity 2/1567 28/18639 0.0714285714285714 0.849621661044763 0.694865728727617 0.879611989417138 GO:0019789 SUMO transferase activity 2/1567 28/18639 0.0714285714285714 0.849621661044763 0.694865728727617 0.879611989417138 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 2/1567 28/18639 0.0714285714285714 0.849621661044763 0.694865728727617 0.879611989417138 GO:0004843 cysteine-type deubiquitinase activity 8/1567 108/18639 0.0740740740740741 0.881089129972346 0.696588994323411 0.879611989417138 GO:0016859 cis-trans isomerase activity 3/1567 42/18639 0.0714285714285714 0.849621661044763 0.697404958612313 0.879611989417138 GO:0015108 chloride transmembrane transporter activity 9/1567 121/18639 0.0743801652892562 0.884729994145786 0.697453262926677 0.879611989417138 GO:0019212 phosphatase inhibitor activity 4/1567 56/18639 0.0714285714285714 0.849621661044763 0.703735657330383 0.879611989417138 GO:0140030 modification-dependent protein binding 13/1567 173/18639 0.0751445086705202 0.893821631850559 0.704143363585753 0.879611989417138 GO:0004705 JUN kinase activity 1/1567 14/18639 0.0714285714285714 0.849621661044763 0.707672014320328 0.879611989417138 GO:0008331 high voltage-gated calcium channel activity 1/1567 14/18639 0.0714285714285714 0.849621661044763 0.707672014320328 0.879611989417138 GO:0008392 arachidonate epoxygenase activity 1/1567 14/18639 0.0714285714285714 0.849621661044763 0.707672014320328 0.879611989417138 GO:0008494 translation activator activity 1/1567 14/18639 0.0714285714285714 0.849621661044763 0.707672014320328 0.879611989417138 GO:0015926 glucosidase activity 1/1567 14/18639 0.0714285714285714 0.849621661044763 0.707672014320328 0.879611989417138 GO:0019763 immunoglobulin receptor activity 1/1567 14/18639 0.0714285714285714 0.849621661044763 0.707672014320328 0.879611989417138 GO:0019992 diacylglycerol binding 1/1567 14/18639 0.0714285714285714 0.849621661044763 0.707672014320328 0.879611989417138 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/1567 14/18639 0.0714285714285714 0.849621661044763 0.707672014320328 0.879611989417138 GO:0030983 mismatched DNA binding 1/1567 14/18639 0.0714285714285714 0.849621661044763 0.707672014320328 0.879611989417138 GO:0034236 protein kinase A catalytic subunit binding 1/1567 14/18639 0.0714285714285714 0.849621661044763 0.707672014320328 0.879611989417138 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/1567 14/18639 0.0714285714285714 0.849621661044763 0.707672014320328 0.879611989417138 GO:0042043 neurexin family protein binding 1/1567 14/18639 0.0714285714285714 0.849621661044763 0.707672014320328 0.879611989417138 GO:0061665 SUMO ligase activity 1/1567 14/18639 0.0714285714285714 0.849621661044763 0.707672014320328 0.879611989417138 GO:0061783 peptidoglycan muralytic activity 1/1567 14/18639 0.0714285714285714 0.849621661044763 0.707672014320328 0.879611989417138 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/1567 14/18639 0.0714285714285714 0.849621661044763 0.707672014320328 0.879611989417138 GO:0098821 BMP receptor activity 1/1567 14/18639 0.0714285714285714 0.849621661044763 0.707672014320328 0.879611989417138 GO:1901612 cardiolipin binding 1/1567 14/18639 0.0714285714285714 0.849621661044763 0.707672014320328 0.879611989417138 GO:0003785 actin monomer binding 2/1567 29/18639 0.0689655172413793 0.820324362388047 0.71335726702106 0.879611989417138 GO:0004181 metallocarboxypeptidase activity 2/1567 29/18639 0.0689655172413793 0.820324362388047 0.71335726702106 0.879611989417138 GO:0004629 phospholipase C activity 2/1567 29/18639 0.0689655172413793 0.820324362388047 0.71335726702106 0.879611989417138 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 2/1567 29/18639 0.0689655172413793 0.820324362388047 0.71335726702106 0.879611989417138 GO:0016417 S-acyltransferase activity 2/1567 29/18639 0.0689655172413793 0.820324362388047 0.71335726702106 0.879611989417138 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 2/1567 29/18639 0.0689655172413793 0.820324362388047 0.71335726702106 0.879611989417138 GO:0097472 cyclin-dependent protein kinase activity 2/1567 29/18639 0.0689655172413793 0.820324362388047 0.71335726702106 0.879611989417138 GO:0099604 ligand-gated calcium channel activity 2/1567 29/18639 0.0689655172413793 0.820324362388047 0.71335726702106 0.879611989417138 GO:0106222 lncRNA binding 2/1567 29/18639 0.0689655172413793 0.820324362388047 0.71335726702106 0.879611989417138 GO:0099094 ligand-gated monoatomic cation channel activity 10/1567 136/18639 0.0735294117647059 0.874610533428432 0.716215801123012 0.882230950921783 GO:0005261 monoatomic cation channel activity 26/1567 341/18639 0.0762463343108504 0.906927520880626 0.728306033864003 0.887439385803867 GO:0008408 3'-5' exonuclease activity 4/1567 58/18639 0.0689655172413793 0.820324362388047 0.729694005197034 0.887439385803867 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 2/1567 30/18639 0.0666666666666667 0.792980216975112 0.730898642311111 0.887439385803867 GO:0016769 transferase activity, transferring nitrogenous groups 2/1567 30/18639 0.0666666666666667 0.792980216975112 0.730898642311111 0.887439385803867 GO:0098918 structural constituent of synapse 2/1567 30/18639 0.0666666666666667 0.792980216975112 0.730898642311111 0.887439385803867 GO:0004129 cytochrome-c oxidase activity 1/1567 15/18639 0.0666666666666667 0.792980216975112 0.732266803773216 0.887439385803867 GO:0004559 alpha-mannosidase activity 1/1567 15/18639 0.0666666666666667 0.792980216975112 0.732266803773216 0.887439385803867 GO:0005523 tropomyosin binding 1/1567 15/18639 0.0666666666666667 0.792980216975112 0.732266803773216 0.887439385803867 GO:0008020 G protein-coupled photoreceptor activity 1/1567 15/18639 0.0666666666666667 0.792980216975112 0.732266803773216 0.887439385803867 GO:0010181 FMN binding 1/1567 15/18639 0.0666666666666667 0.792980216975112 0.732266803773216 0.887439385803867 GO:0017081 chloride channel regulator activity 1/1567 15/18639 0.0666666666666667 0.792980216975112 0.732266803773216 0.887439385803867 GO:0030553 cGMP binding 1/1567 15/18639 0.0666666666666667 0.792980216975112 0.732266803773216 0.887439385803867 GO:0042809 nuclear vitamin D receptor binding 1/1567 15/18639 0.0666666666666667 0.792980216975112 0.732266803773216 0.887439385803867 GO:0045504 dynein heavy chain binding 1/1567 15/18639 0.0666666666666667 0.792980216975112 0.732266803773216 0.887439385803867 GO:0048531 beta-1,3-galactosyltransferase activity 1/1567 15/18639 0.0666666666666667 0.792980216975112 0.732266803773216 0.887439385803867 GO:0050780 dopamine receptor binding 1/1567 15/18639 0.0666666666666667 0.792980216975112 0.732266803773216 0.887439385803867 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 17/1567 229/18639 0.074235807860262 0.883012905365299 0.739185061148594 0.894115947678744 GO:0070063 RNA polymerase binding 4/1567 59/18639 0.0677966101694915 0.806420559635707 0.742017989335721 0.894115947678744 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 5/1567 73/18639 0.0684931506849315 0.81470570237169 0.745381460013704 0.894115947678744 GO:0005310 dicarboxylic acid transmembrane transporter activity 2/1567 31/18639 0.0645161290322581 0.767400209975915 0.747518809440678 0.894115947678744 GO:0008327 methyl-CpG binding 2/1567 31/18639 0.0645161290322581 0.767400209975915 0.747518809440678 0.894115947678744 GO:0047499 calcium-independent phospholipase A2 activity 2/1567 31/18639 0.0645161290322581 0.767400209975915 0.747518809440678 0.894115947678744 GO:0004519 endonuclease activity 9/1567 127/18639 0.0708661417322835 0.842931726705827 0.750318813008393 0.894115947678744 GO:0019783 ubiquitin-like protein peptidase activity 9/1567 127/18639 0.0708661417322835 0.842931726705827 0.750318813008393 0.894115947678744 GO:0000062 fatty-acyl-CoA binding 1/1567 16/18639 0.0625 0.743418953414167 0.754793539087186 0.894115947678744 GO:0003688 DNA replication origin binding 1/1567 16/18639 0.0625 0.743418953414167 0.754793539087186 0.894115947678744 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 1/1567 16/18639 0.0625 0.743418953414167 0.754793539087186 0.894115947678744 GO:0004707 MAP kinase activity 1/1567 16/18639 0.0625 0.743418953414167 0.754793539087186 0.894115947678744 GO:0005024 transforming growth factor beta receptor activity 1/1567 16/18639 0.0625 0.743418953414167 0.754793539087186 0.894115947678744 GO:0005521 lamin binding 1/1567 16/18639 0.0625 0.743418953414167 0.754793539087186 0.894115947678744 GO:0008296 3'-5'-DNA exonuclease activity 1/1567 16/18639 0.0625 0.743418953414167 0.754793539087186 0.894115947678744 GO:0008391 arachidonate monooxygenase activity 1/1567 16/18639 0.0625 0.743418953414167 0.754793539087186 0.894115947678744 GO:0015562 efflux transmembrane transporter activity 1/1567 16/18639 0.0625 0.743418953414167 0.754793539087186 0.894115947678744 GO:0015923 mannosidase activity 1/1567 16/18639 0.0625 0.743418953414167 0.754793539087186 0.894115947678744 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/1567 16/18639 0.0625 0.743418953414167 0.754793539087186 0.894115947678744 GO:0017070 U6 snRNA binding 1/1567 16/18639 0.0625 0.743418953414167 0.754793539087186 0.894115947678744 GO:0019841 retinol binding 1/1567 16/18639 0.0625 0.743418953414167 0.754793539087186 0.894115947678744 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/1567 16/18639 0.0625 0.743418953414167 0.754793539087186 0.894115947678744 GO:0030276 clathrin binding 3/1567 46/18639 0.0652173913043478 0.775741516606087 0.754898893377391 0.894115947678744 GO:0016651 oxidoreductase activity, acting on NAD(P)H 6/1567 88/18639 0.0681818181818182 0.811002494633637 0.759765913831306 0.898687779614112 GO:0101005 deubiquitinase activity 8/1567 115/18639 0.0695652173913043 0.82745761771316 0.760808830978801 0.898687779614112 GO:0022884 macromolecule transmembrane transporter activity 2/1567 32/18639 0.0625 0.743418953414167 0.763248572195166 0.898687779614112 GO:0030515 snoRNA binding 2/1567 32/18639 0.0625 0.743418953414167 0.763248572195166 0.898687779614112 GO:0031369 translation initiation factor binding 2/1567 32/18639 0.0625 0.743418953414167 0.763248572195166 0.898687779614112 GO:0047498 calcium-dependent phospholipase A2 activity 2/1567 32/18639 0.0625 0.743418953414167 0.763248572195166 0.898687779614112 GO:0140938 histone H3 methyltransferase activity 3/1567 47/18639 0.0638297872340425 0.759236377954894 0.76781374438341 0.903177577869222 GO:0022843 voltage-gated monoatomic cation channel activity 10/1567 143/18639 0.0699300699300699 0.831797430393474 0.772064528599274 0.904161785630355 GO:0004549 tRNA-specific ribonuclease activity 1/1567 17/18639 0.0588235294117647 0.699688426742746 0.775426010990229 0.904161785630355 GO:0004550 nucleoside diphosphate kinase activity 1/1567 17/18639 0.0588235294117647 0.699688426742746 0.775426010990229 0.904161785630355 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/1567 17/18639 0.0588235294117647 0.699688426742746 0.775426010990229 0.904161785630355 GO:0009881 photoreceptor activity 1/1567 17/18639 0.0588235294117647 0.699688426742746 0.775426010990229 0.904161785630355 GO:0015278 intracellularly gated calcium channel activity 1/1567 17/18639 0.0588235294117647 0.699688426742746 0.775426010990229 0.904161785630355 GO:0016805 dipeptidase activity 1/1567 17/18639 0.0588235294117647 0.699688426742746 0.775426010990229 0.904161785630355 GO:0030548 acetylcholine receptor regulator activity 1/1567 17/18639 0.0588235294117647 0.699688426742746 0.775426010990229 0.904161785630355 GO:1901567 fatty acid derivative binding 1/1567 17/18639 0.0588235294117647 0.699688426742746 0.775426010990229 0.904161785630355 GO:0042923 neuropeptide binding 2/1567 33/18639 0.0606060606060606 0.720891106341011 0.778120068249519 0.906423086292601 GO:0016879 ligase activity, forming carbon-nitrogen bonds 3/1567 48/18639 0.0625 0.743418953414167 0.78016787746064 0.907049003707869 GO:0032266 phosphatidylinositol-3-phosphate binding 3/1567 48/18639 0.0625 0.743418953414167 0.78016787746064 0.907049003707869 GO:0022853 active monoatomic ion transmembrane transporter activity 8/1567 118/18639 0.0677966101694915 0.806420559635707 0.785159400248426 0.911969477464565 GO:0015078 proton transmembrane transporter activity 13/1567 185/18639 0.0702702702702703 0.83584401248728 0.78842924852033 0.913776264692046 GO:0008175 tRNA methyltransferase activity 2/1567 34/18639 0.0588235294117647 0.699688426742746 0.79216632755541 0.913776264692046 GO:0052866 phosphatidylinositol phosphate phosphatase activity 2/1567 34/18639 0.0588235294117647 0.699688426742746 0.79216632755541 0.913776264692046 GO:0000400 four-way junction DNA binding 1/1567 18/18639 0.0555555555555556 0.66081684747926 0.79432341410366 0.913776264692046 GO:0003746 translation elongation factor activity 1/1567 18/18639 0.0555555555555556 0.66081684747926 0.79432341410366 0.913776264692046 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/1567 18/18639 0.0555555555555556 0.66081684747926 0.79432341410366 0.913776264692046 GO:0022851 GABA-gated chloride ion channel activity 1/1567 18/18639 0.0555555555555556 0.66081684747926 0.79432341410366 0.913776264692046 GO:0035615 clathrin adaptor activity 1/1567 18/18639 0.0555555555555556 0.66081684747926 0.79432341410366 0.913776264692046 GO:0050811 GABA receptor binding 1/1567 18/18639 0.0555555555555556 0.66081684747926 0.79432341410366 0.913776264692046 GO:0070064 proline-rich region binding 1/1567 18/18639 0.0555555555555556 0.66081684747926 0.79432341410366 0.913776264692046 GO:0004536 DNA nuclease activity 4/1567 64/18639 0.0625 0.743418953414167 0.79726724285772 0.916285127915906 GO:0004623 phospholipase A2 activity 2/1567 35/18639 0.0571428571428571 0.67969732883581 0.8054208954729 0.924771028167258 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/1567 19/18639 0.0526315789473684 0.626037013401404 0.81163157210267 0.925704482520935 GO:0004890 GABA-A receptor activity 1/1567 19/18639 0.0526315789473684 0.626037013401404 0.81163157210267 0.925704482520935 GO:0005229 intracellularly calcium-gated chloride channel activity 1/1567 19/18639 0.0526315789473684 0.626037013401404 0.81163157210267 0.925704482520935 GO:0008574 plus-end-directed microtubule motor activity 1/1567 19/18639 0.0526315789473684 0.626037013401404 0.81163157210267 0.925704482520935 GO:0070003 threonine-type peptidase activity 1/1567 19/18639 0.0526315789473684 0.626037013401404 0.81163157210267 0.925704482520935 GO:0120227 acyl-CoA binding 1/1567 19/18639 0.0526315789473684 0.626037013401404 0.81163157210267 0.925704482520935 GO:0141147 intracellularly calcium-gated channel activity 1/1567 19/18639 0.0526315789473684 0.626037013401404 0.81163157210267 0.925704482520935 GO:0003743 translation initiation factor activity 3/1567 51/18639 0.0588235294117647 0.699688426742746 0.814003540513828 0.925704482520935 GO:0005048 signal sequence binding 3/1567 51/18639 0.0588235294117647 0.699688426742746 0.814003540513828 0.925704482520935 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 8/1567 122/18639 0.0655737704918033 0.779980541286995 0.814712437988866 0.925704482520935 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 8/1567 122/18639 0.0655737704918033 0.779980541286995 0.814712437988866 0.925704482520935 GO:0004033 aldo-keto reductase (NADPH) activity 2/1567 36/18639 0.0555555555555556 0.66081684747926 0.817917512892483 0.927591060419142 GO:0016409 palmitoyltransferase activity 2/1567 36/18639 0.0555555555555556 0.66081684747926 0.817917512892483 0.927591060419142 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 3/1567 52/18639 0.0576923076923077 0.686232880074616 0.824255937881139 0.933897529618159 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/1567 20/18639 0.05 0.594735162731334 0.827484060100259 0.934909083895025 GO:0016408 C-acyltransferase activity 1/1567 20/18639 0.05 0.594735162731334 0.827484060100259 0.934909083895025 GO:0061608 nuclear import signal receptor activity 1/1567 20/18639 0.05 0.594735162731334 0.827484060100259 0.934909083895025 GO:0016251 RNA polymerase II general transcription initiation factor activity 3/1567 53/18639 0.0566037735849057 0.673285089884529 0.834021237434541 0.939009409974202 GO:0051018 protein kinase A binding 3/1567 53/18639 0.0566037735849057 0.673285089884529 0.834021237434541 0.939009409974202 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 3/1567 53/18639 0.0566037735849057 0.673285089884529 0.834021237434541 0.939009409974202 GO:0140223 general transcription initiation factor activity 4/1567 68/18639 0.0588235294117647 0.699688426742746 0.834240666479995 0.939009409974202 GO:0005254 chloride channel activity 5/1567 83/18639 0.0602409638554217 0.716548388832932 0.837472875827118 0.941764909989109 GO:0015125 bile acid transmembrane transporter activity 1/1567 21/18639 0.0476190476190476 0.566414440696508 0.842003232871241 0.942583372750555 GO:0015174 basic amino acid transmembrane transporter activity 1/1567 21/18639 0.0476190476190476 0.566414440696508 0.842003232871241 0.942583372750555 GO:0036122 BMP binding 1/1567 21/18639 0.0476190476190476 0.566414440696508 0.842003232871241 0.942583372750555 GO:0140312 cargo adaptor activity 1/1567 21/18639 0.0476190476190476 0.566414440696508 0.842003232871241 0.942583372750555 GO:0005249 voltage-gated potassium channel activity 6/1567 98/18639 0.0612244897959184 0.728247138038368 0.842124861749664 0.942583372750555 GO:0017069 snRNA binding 3/1567 54/18639 0.0555555555555556 0.66081684747926 0.843315520963251 0.943037188712165 GO:0000217 DNA secondary structure binding 2/1567 39/18639 0.0512820512820513 0.609984782288547 0.851194640332043 0.950962570268636 GO:0008093 cytoskeletal anchor activity 1/1567 22/18639 0.0454545454545455 0.540668329755758 0.855301166811017 0.953775952961961 GO:0070034 telomerase RNA binding 1/1567 22/18639 0.0454545454545455 0.540668329755758 0.855301166811017 0.953775952961961 GO:0005216 monoatomic ion channel activity 32/1567 448/18639 0.0714285714285714 0.849621661044763 0.856847044099693 0.954613450801235 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 3/1567 56/18639 0.0535714285714286 0.637216245783572 0.86055614151577 0.957857206636181 GO:0015276 ligand-gated monoatomic ion channel activity 12/1567 186/18639 0.0645161290322581 0.767400209975915 0.866358867685394 0.960224984292763 GO:0003887 DNA-directed DNA polymerase activity 1/1567 23/18639 0.0434782608695652 0.517161011070725 0.867480522862322 0.960224984292763 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/1567 23/18639 0.0434782608695652 0.517161011070725 0.867480522862322 0.960224984292763 GO:0016917 GABA receptor activity 1/1567 23/18639 0.0434782608695652 0.517161011070725 0.867480522862322 0.960224984292763 GO:0070577 lysine-acetylated histone binding 1/1567 23/18639 0.0434782608695652 0.517161011070725 0.867480522862322 0.960224984292763 GO:0140103 catalytic activity, acting on a glycoprotein 1/1567 23/18639 0.0434782608695652 0.517161011070725 0.867480522862322 0.960224984292763 GO:0140318 protein transporter activity 2/1567 41/18639 0.0487804878048781 0.58022942705496 0.870195464969732 0.962343235201334 GO:0005253 monoatomic anion channel activity 6/1567 103/18639 0.058252427184466 0.692895335220971 0.873800565596128 0.964098757985757 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 8/1567 132/18639 0.0606060606060606 0.720891106341011 0.874889440091781 0.964098757985757 GO:0022834 ligand-gated channel activity 12/1567 188/18639 0.0638297872340425 0.759236377954894 0.875248224151935 0.964098757985757 GO:0140597 protein carrier chaperone 12/1567 188/18639 0.0638297872340425 0.759236377954894 0.875248224151935 0.964098757985757 GO:0140033 acetylation-dependent protein binding 1/1567 24/18639 0.0416666666666667 0.495612635609445 0.878635337036943 0.964098757985757 GO:0019894 kinesin binding 2/1567 42/18639 0.0476190476190476 0.566414440696508 0.878834990287603 0.964098757985757 GO:0043175 RNA polymerase core enzyme binding 2/1567 42/18639 0.0476190476190476 0.566414440696508 0.878834990287603 0.964098757985757 GO:0003684 damaged DNA binding 4/1567 74/18639 0.0540540540540541 0.642956932682523 0.87900761032007 0.964098757985757 GO:0035064 methylated histone binding 4/1567 74/18639 0.0540540540540541 0.642956932682523 0.87900761032007 0.964098757985757 GO:0043021 ribonucleoprotein complex binding 11/1567 177/18639 0.0621468926553672 0.739218846332731 0.887392123697019 0.97223219059158 GO:0008483 transaminase activity 1/1567 25/18639 0.04 0.475788130185067 0.888851744604126 0.97223219059158 GO:0017056 structural constituent of nuclear pore 1/1567 25/18639 0.04 0.475788130185067 0.888851744604126 0.97223219059158 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 3/1567 60/18639 0.05 0.594735162731334 0.890101271791725 0.972713036780584 GO:0140034 methylation-dependent protein binding 4/1567 76/18639 0.0526315789473684 0.626037013401404 0.891401356118132 0.973248207907161 GO:0003724 RNA helicase activity 4/1567 77/18639 0.051948051948052 0.617906662578009 0.897170473052577 0.978013219268961 GO:0034237 protein kinase A regulatory subunit binding 1/1567 26/18639 0.0384615384615385 0.457488586716411 0.898208643508463 0.978013219268961 GO:0120014 phospholipid transfer activity 1/1567 26/18639 0.0384615384615385 0.457488586716411 0.898208643508463 0.978013219268961 GO:0051539 4 iron, 4 sulfur cluster binding 2/1567 45/18639 0.0444444444444444 0.528653477983408 0.901662836830878 0.980885024487214 GO:0016410 N-acyltransferase activity 5/1567 94/18639 0.0531914893617021 0.632696981629079 0.905252138445846 0.982033088489939 GO:0140767 enzyme-substrate adaptor activity 8/1567 139/18639 0.0575539568345324 0.684587237676355 0.906649674764383 0.982033088489939 GO:0005104 fibroblast growth factor receptor binding 1/1567 27/18639 0.037037037037037 0.440544564986173 0.906778302113859 0.982033088489939 GO:0008395 steroid hydroxylase activity 1/1567 27/18639 0.037037037037037 0.440544564986173 0.906778302113859 0.982033088489939 GO:0008186 ATP-dependent activity, acting on RNA 4/1567 79/18639 0.0506329113924051 0.602263455930465 0.907903959896183 0.982033088489939 GO:0022824 transmitter-gated monoatomic ion channel activity 3/1567 63/18639 0.0476190476190476 0.566414440696508 0.908441932816255 0.982033088489939 GO:0022835 transmitter-gated channel activity 3/1567 63/18639 0.0476190476190476 0.566414440696508 0.908441932816255 0.982033088489939 GO:0061749 forked DNA-dependent helicase activity 2/1567 47/18639 0.0425531914893617 0.506157585303263 0.914579266537952 0.984289360257633 GO:0099095 ligand-gated monoatomic anion channel activity 2/1567 47/18639 0.0425531914893617 0.506157585303263 0.914579266537952 0.984289360257633 GO:1990518 single-stranded 3'-5' DNA helicase activity 2/1567 47/18639 0.0425531914893617 0.506157585303263 0.914579266537952 0.984289360257633 GO:0005242 inward rectifier potassium channel activity 1/1567 28/18639 0.0357142857142857 0.424810830522381 0.914626915942979 0.984289360257633 GO:0016866 intramolecular transferase activity 1/1567 28/18639 0.0357142857142857 0.424810830522381 0.914626915942979 0.984289360257633 GO:0030594 neurotransmitter receptor activity 5/1567 97/18639 0.0515463917525773 0.613129033743643 0.918810779016438 0.985230223895981 GO:0019843 rRNA binding 3/1567 65/18639 0.0461538461538462 0.548986304059693 0.919078303925164 0.985230223895981 GO:0008188 neuropeptide receptor activity 2/1567 48/18639 0.0416666666666667 0.495612635609445 0.920423239976095 0.985230223895981 GO:0009378 four-way junction helicase activity 2/1567 48/18639 0.0416666666666667 0.495612635609445 0.920423239976095 0.985230223895981 GO:0036121 double-stranded DNA helicase activity 2/1567 48/18639 0.0416666666666667 0.495612635609445 0.920423239976095 0.985230223895981 GO:0043138 3'-5' DNA helicase activity 2/1567 48/18639 0.0416666666666667 0.495612635609445 0.920423239976095 0.985230223895981 GO:0005244 voltage-gated monoatomic ion channel activity 10/1567 173/18639 0.0578034682080925 0.687555101423507 0.924069441452592 0.988252359024544 GO:0008135 translation factor activity, RNA binding 4/1567 83/18639 0.0481927710843374 0.573238711066346 0.926427613499525 0.989892850367375 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/1567 30/18639 0.0333333333333333 0.396490108487556 0.9283984444274 0.990424408614263 GO:0042054 histone methyltransferase activity 3/1567 67/18639 0.0447761194029851 0.532598653192239 0.928574424729109 0.990424408614263 GO:0022832 voltage-gated channel activity 10/1567 175/18639 0.0571428571428571 0.67969732883581 0.930015655261035 0.990719285132182 GO:0180051 translation factor activity 4/1567 84/18639 0.0476190476190476 0.566414440696508 0.93050071076528 0.990719285132182 GO:0005184 neuropeptide hormone activity 1/1567 31/18639 0.032258064516129 0.383700104987957 0.934427765593624 0.992399124862333 GO:0070273 phosphatidylinositol-4-phosphate binding 1/1567 31/18639 0.032258064516129 0.383700104987957 0.934427765593624 0.992399124862333 GO:0022836 gated channel activity 20/1567 318/18639 0.0628930817610063 0.748094544316143 0.934850705640719 0.992399124862333 GO:0140104 molecular carrier activity 15/1567 249/18639 0.0602409638554217 0.716548388832932 0.936290913766535 0.992399124862333 GO:0016279 protein-lysine N-methyltransferase activity 3/1567 69/18639 0.0434782608695652 0.517161011070725 0.937036309403735 0.992399124862333 GO:0098960 postsynaptic neurotransmitter receptor activity 3/1567 69/18639 0.0434782608695652 0.517161011070725 0.937036309403735 0.992399124862333 GO:0140142 nucleocytoplasmic carrier activity 1/1567 32/18639 0.03125 0.371709476707084 0.939949675058091 0.993732006817577 GO:0160041 neuropeptide activity 1/1567 32/18639 0.03125 0.371709476707084 0.939949675058091 0.993732006817577 GO:0016278 lysine N-methyltransferase activity 3/1567 70/18639 0.0428571428571429 0.509772996626857 0.940910642825813 0.993873071269834 GO:0140299 molecular sensor activity 3/1567 71/18639 0.0422535211267606 0.502593095265916 0.944563008397917 0.996854282149296 GO:0016874 ligase activity 9/1567 167/18639 0.0538922155688623 0.641031911925989 0.947522920898784 0.99870025910328 GO:0015020 glucuronosyltransferase activity 1/1567 34/18639 0.0294117647058824 0.349844213371373 0.949638381262236 0.99870025910328 GO:0016831 carboxy-lyase activity 1/1567 34/18639 0.0294117647058824 0.349844213371373 0.949638381262236 0.99870025910328 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/1567 34/18639 0.0294117647058824 0.349844213371373 0.949638381262236 0.99870025910328 GO:0010485 histone H4 acetyltransferase activity 1/1567 35/18639 0.0285714285714286 0.339848664417905 0.953880072020746 0.999999999890819 GO:0034061 DNA polymerase activity 1/1567 35/18639 0.0285714285714286 0.339848664417905 0.953880072020746 0.999999999890819 GO:0031491 nucleosome binding 3/1567 74/18639 0.0405405405405405 0.482217699511892 0.954298838776565 0.999999999890819 GO:0000993 RNA polymerase II complex binding 1/1567 36/18639 0.0277777777777778 0.33040842373963 0.957764716567267 0.999999999890819 GO:0019213 deacetylase activity 1/1567 37/18639 0.027027027027027 0.321478466341261 0.961322351848625 0.999999999890819 GO:0030280 structural constituent of skin epidermis 1/1567 37/18639 0.027027027027027 0.321478466341261 0.961322351848625 0.999999999890819 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 2/1567 58/18639 0.0344827586206897 0.410162181194023 0.961395788282881 0.999999999890819 GO:0017116 single-stranded DNA helicase activity 2/1567 58/18639 0.0344827586206897 0.410162181194023 0.961395788282881 0.999999999890819 GO:0005109 frizzled binding 1/1567 38/18639 0.0263157894736842 0.313018506700702 0.964580489395835 0.999999999890819 GO:0042887 amide transmembrane transporter activity 1/1567 38/18639 0.0263157894736842 0.313018506700702 0.964580489395835 0.999999999890819 GO:0016407 acetyltransferase activity 4/1567 96/18639 0.0416666666666667 0.495612635609445 0.965704153440474 0.999999999890819 GO:0071855 neuropeptide receptor binding 1/1567 40/18639 0.025 0.297367581365667 0.970296945742099 0.999999999890819 GO:0140713 histone chaperone activity 8/1567 164/18639 0.0487804878048781 0.58022942705496 0.970447597132185 0.999999999890819 GO:0009055 electron transfer activity 5/1567 116/18639 0.0431034482758621 0.512702726492529 0.971272988978795 0.999999999890819 GO:0000510 H3-H4 histone complex chaperone activity 7/1567 151/18639 0.0463576158940397 0.551410084651568 0.974452439192723 0.999999999890819 GO:0140584 chromatin extrusion motor activity 7/1567 151/18639 0.0463576158940397 0.551410084651568 0.974452439192723 0.999999999890819 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 7/1567 151/18639 0.0463576158940397 0.551410084651568 0.974452439192723 0.999999999890819 GO:0140849 ATP-dependent H2AZ histone chaperone activity 7/1567 151/18639 0.0463576158940397 0.551410084651568 0.974452439192723 0.999999999890819 GO:0004402 histone acetyltransferase activity 1/1567 42/18639 0.0238095238095238 0.283207220348254 0.975091299651013 0.999999999890819 GO:0004520 DNA endonuclease activity 1/1567 42/18639 0.0238095238095238 0.283207220348254 0.975091299651013 0.999999999890819 GO:0031492 nucleosomal DNA binding 1/1567 42/18639 0.0238095238095238 0.283207220348254 0.975091299651013 0.999999999890819 GO:0015616 DNA translocase activity 7/1567 152/18639 0.0460526315789474 0.547782386726228 0.975744540846474 0.999999999890819 GO:0140674 ATP-dependent histone chaperone activity 7/1567 152/18639 0.0460526315789474 0.547782386726228 0.975744540846474 0.999999999890819 GO:0061775 cohesin loader activity 7/1567 153/18639 0.0457516339869281 0.544202109688802 0.976976229576038 0.999999999890819 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/1567 43/18639 0.0232558139534884 0.276621005921551 0.977190129217441 0.999999999890819 GO:0004842 ubiquitin-protein transferase activity 27/1567 449/18639 0.0601336302895323 0.715271687917417 0.977798478569488 0.999999999890819 GO:0003697 single-stranded DNA binding 5/1567 121/18639 0.0413223140495868 0.491516663414325 0.97847628787998 0.999999999890819 GO:0003954 NADH dehydrogenase activity 1/1567 44/18639 0.0227272727272727 0.270334164877879 0.979112212865337 0.999999999890819 GO:0004386 helicase activity 7/1567 155/18639 0.0451612903225806 0.53718014698314 0.979268299502372 0.999999999890819 GO:0008173 RNA methyltransferase activity 2/1567 67/18639 0.0298507462686567 0.355065768794826 0.980242153159757 0.999999999890819 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 2/1567 68/18639 0.0294117647058824 0.349844213371373 0.981675906573858 0.999999999890819 GO:0140658 ATP-dependent chromatin remodeler activity 7/1567 158/18639 0.0443037974683544 0.526980523939157 0.982313232780962 0.999999999890819 GO:0008080 N-acetyltransferase activity 2/1567 69/18639 0.0289855072463768 0.344774007380483 0.983008431862518 0.999999999890819 GO:0061733 protein-lysine-acetyltransferase activity 1/1567 47/18639 0.0212765957446809 0.253078792651631 0.983960591034741 0.999999999890819 GO:0003689 DNA clamp loader activity 7/1567 160/18639 0.04375 0.520393267389917 0.984106525329487 0.999999999890819 GO:0019787 ubiquitin-like protein transferase activity 28/1567 479/18639 0.058455114822547 0.695306244529325 0.986880229391834 0.999999999890819 GO:0043022 ribosome binding 4/1567 112/18639 0.0357142857142857 0.424810830522381 0.98735039383895 0.999999999890819 GO:0016755 aminoacyltransferase activity 29/1567 496/18639 0.0584677419354839 0.695456440290673 0.988063507043069 0.999999999890819 GO:0003678 DNA helicase activity 2/1567 74/18639 0.027027027027027 0.321478466341261 0.988378342902999 0.999999999890819 GO:0008276 protein methyltransferase activity 3/1567 95/18639 0.0315789473684211 0.375622208040842 0.988869750252732 0.999999999890819 GO:0051536 iron-sulfur cluster binding 2/1567 76/18639 0.0263157894736842 0.313018506700702 0.990026799313219 0.999999999890819 GO:0034212 protein N-acetyltransferase activity 1/1567 53/18639 0.0188679245283019 0.224428363294843 0.990543679930056 0.999999999890819 GO:0140098 catalytic activity, acting on RNA 21/1567 387/18639 0.0542635658914729 0.645449013816951 0.990556670091874 0.999999999890819 GO:0051540 metal cluster binding 2/1567 77/18639 0.025974025974026 0.308953331289005 0.990763070350964 0.999999999890819 GO:0008170 N-methyltransferase activity 3/1567 98/18639 0.0306122448979592 0.364123569019184 0.990969168803786 0.999999999890819 GO:0140101 catalytic activity, acting on a tRNA 5/1567 139/18639 0.0359712230215827 0.427867023547722 0.99270971509029 0.999999999890819 GO:0061630 ubiquitin protein ligase activity 18/1567 353/18639 0.0509915014164306 0.606528777856318 0.993898394686632 0.999999999890819 GO:0003730 mRNA 3'-UTR binding 12/1567 262/18639 0.0458015267175573 0.544795568914199 0.994491174715005 0.999999999890819 GO:0061659 ubiquitin-like protein ligase activity 19/1567 372/18639 0.0510752688172043 0.607525166230932 0.994807110919417 0.999999999890819 GO:0019905 syntaxin binding 1/1567 61/18639 0.0163934426229508 0.194995135321749 0.995326451549591 0.999999999890819 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 5/1567 167/18639 0.029940119760479 0.356128839958883 0.998787242564005 0.999999999890819 GO:0008094 ATP-dependent activity, acting on DNA 7/1567 210/18639 0.0333333333333333 0.396490108487556 0.999119716020276 0.999999999890819 GO:0000049 tRNA binding 1/1567 80/18639 0.0125 0.148683790682833 0.999124683536802 0.999999999890819 GO:0008168 methyltransferase activity 6/1567 204/18639 0.0294117647058824 0.349844213371373 0.999614458988014 0.999999999890819 GO:0140097 catalytic activity, acting on DNA 13/1567 336/18639 0.0386904761904762 0.460211733065913 0.999714269708279 0.999999999890819 GO:0016741 transferase activity, transferring one-carbon groups 6/1567 215/18639 0.027906976744186 0.331945207105861 0.999813354881739 0.999999999890819 GO:0003735 structural constituent of ribosome 1/1567 175/18639 0.00571428571428571 0.067969732883581 0.999999803646641 0.999999999890819 GO:0045182 translation regulator activity 6/1567 356/18639 0.0168539325842697 0.200472526763371 0.999999992463899 0.999999999890819 GO:0030371 translation repressor activity 3/1567 329/18639 0.00911854103343465 0.108462339707842 0.999999999890819 0.999999999890819