ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003779	actin binding	121/2411	443/18639	0.27313769751693	2.11157757943511	2.3737585406228e-16	3.06214851740341e-13
GO:0005516	calmodulin binding	58/2411	207/18639	0.280193236714976	2.16612266243485	5.3844046077042e-09	3.47294097196921e-06
GO:0005201	extracellular matrix structural constituent	47/2411	168/18639	0.279761904761905	2.1627881140013	1.54745091473945e-07	6.65403893337965e-05
GO:0005520	insulin-like growth factor binding	12/2411	19/18639	0.631578947368421	4.88262131895479	4.46106009641532e-07	0.000143869188109394
GO:0071889	14-3-3 protein binding	16/2411	33/18639	0.484848484848485	3.74827495192489	7.72270081357358e-07	0.000166261608103236
GO:0005178	integrin binding	44/2411	161/18639	0.273291925465839	2.11276988749804	7.73309805131329e-07	0.000166261608103236
GO:0042805	actinin binding	17/2411	37/18639	0.459459459459459	3.55199704059098	9.13515733370489e-07	0.000168347899435419
GO:0005518	collagen binding	25/2411	72/18639	0.347222222222222	2.68431148900871	1.81400590266548e-06	0.000268029401774435
GO:0045296	cadherin binding	74/2411	334/18639	0.221556886227545	1.71281576208843	1.86997257051931e-06	0.000268029401774435
GO:0051371	muscle alpha-actinin binding	10/2411	15/18639	0.666666666666667	5.15387805889672	2.08086751133115e-06	0.000268431908961718
GO:0019838	growth factor binding	38/2411	136/18639	0.279411764705882	2.16008124527289	2.38626829494532e-06	0.000279844190952678
GO:0031994	insulin-like growth factor I binding	9/2411	13/18639	0.692307692307692	5.35210413808506	4.37320766255847e-06	0.000470119823725035
GO:0004674	protein serine/threonine kinase activity	89/2411	433/18639	0.20554272517321	1.58901321215407	4.95677944980633e-06	0.000491865037711551
GO:0050840	extracellular matrix binding	23/2411	67/18639	0.343283582089552	2.65386258256622	5.7918471083253e-06	0.000533677340695688
GO:0106310	protein serine kinase activity	76/2411	361/18639	0.210526315789474	1.6275404396516	9.87349231588588e-06	0.000849120339166185
GO:0019902	phosphatase binding	46/2411	190/18639	0.242105263157895	1.87167150559934	1.54315600969757e-05	0.00117276229636929
GO:0051393	alpha-actinin binding	13/2411	28/18639	0.464285714285714	3.5893079338745	1.5455007006417e-05	0.00117276229636929
GO:0005539	glycosaminoglycan binding	54/2411	242/18639	0.223140495867769	1.72505835855634	3.56164029342277e-05	0.00255250887695299
GO:0001968	fibronectin binding	13/2411	30/18639	0.433333333333333	3.35002073828287	3.84388940285937e-05	0.00260979859457294
GO:0051015	actin filament binding	48/2411	209/18639	0.229665071770335	1.77549866143811	4.40274915009442e-05	0.0028397732018109
GO:0141003	histone H2AX kinase activity	72/2411	354/18639	0.203389830508475	1.57236957729053	5.47856779590335e-05	0.0033654059317692
GO:0019903	protein phosphatase binding	36/2411	144/18639	0.25	1.93270427208627	6.11446638421216e-05	0.00358530074346986
GO:0140996	histone H3 kinase activity	72/2411	357/18639	0.201680672268908	1.5591563875654	7.25111434893941e-05	0.00406692935223123
GO:0050431	transforming growth factor beta binding	11/2411	24/18639	0.458333333333333	3.5432911654915	8.18277510189222e-05	0.00439824161726707
GO:0035173	histone kinase activity	72/2411	360/18639	0.2	1.54616341766902	9.53721450243575e-05	0.00492120268325685
GO:0051117	ATPase binding	24/2411	84/18639	0.285714285714286	2.20880488238431	0.000111759427324293	0.00537825445080416
GO:0005161	platelet-derived growth factor receptor binding	8/2411	14/18639	0.571428571428571	4.41760976476862	0.00011256811641218	0.00537825445080416
GO:0008307	structural constituent of muscle	15/2411	42/18639	0.357142857142857	2.76100610298039	0.000144179688103769	0.00664256420192365
GO:0019199	transmembrane receptor protein kinase activity	22/2411	78/18639	0.282051282051282	2.18048687107169	0.00026009840661087	0.0115698946388973
GO:0140297	DNA-binding transcription factor binding	90/2411	488/18639	0.184426229508197	1.42576544662102	0.000287045032845311	0.012024695479796
GO:0008201	heparin binding	39/2411	172/18639	0.226744186046512	1.75291782817127	0.000288965550289671	0.012024695479796
GO:0031418	L-ascorbic acid binding	9/2411	20/18639	0.45	3.47886768975529	0.000437065672782771	0.0176192099340555
GO:0004679	AMP-activated protein kinase activity	51/2411	248/18639	0.205645161290323	1.58980512703871	0.000479422349028448	0.0187410554620211
GO:0043236	laminin binding	11/2411	29/18639	0.379310344827586	2.93237889557917	0.000611201980307141	0.0231897221940062
GO:0031267	small GTPase binding	56/2411	283/18639	0.197879858657244	1.52977299274673	0.000706354974830201	0.0251427146790663
GO:0035402	histone H3T11 kinase activity	50/2411	247/18639	0.202429149797571	1.56494273043423	0.000785385543128565	0.0251427146790663
GO:0004713	protein tyrosine kinase activity	32/2411	140/18639	0.228571428571429	1.76704390590745	0.000837944244431415	0.0251427146790663
GO:0048029	monosaccharide binding	20/2411	74/18639	0.27027027027027	2.08941002387705	0.000883574795039184	0.0251427146790663
GO:0001222	transcription corepressor binding	15/2411	49/18639	0.306122448979592	2.36657665969748	0.000953229304039065	0.0251427146790663
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	49/2411	243/18639	0.201646090534979	1.5588890425058	0.000962051845919855	0.0251427146790663
GO:0003712	transcription coregulator activity	88/2411	495/18639	0.177777777777778	1.37436748237246	0.00110115145270146	0.0251427146790663
GO:0004843	cysteine-type deubiquitinase activity	26/2411	108/18639	0.240740740740741	1.86112263237937	0.00111349173034334	0.0251427146790663
GO:0004676	3-phosphoinositide-dependent protein kinase activity	49/2411	245/18639	0.2	1.54616341766902	0.00115744081966843	0.0251427146790663
GO:0004711	ribosomal protein S6 kinase activity	49/2411	245/18639	0.2	1.54616341766902	0.00115744081966843	0.0251427146790663
GO:0035175	histone H3S10 kinase activity	49/2411	245/18639	0.2	1.54616341766902	0.00115744081966843	0.0251427146790663
GO:0035979	histone H2AXS139 kinase activity	49/2411	245/18639	0.2	1.54616341766902	0.00115744081966843	0.0251427146790663
GO:0044022	histone H3S28 kinase activity	49/2411	245/18639	0.2	1.54616341766902	0.00115744081966843	0.0251427146790663
GO:0044023	histone H4S1 kinase activity	49/2411	245/18639	0.2	1.54616341766902	0.00115744081966843	0.0251427146790663
GO:0044024	histone H2AS1 kinase activity	49/2411	245/18639	0.2	1.54616341766902	0.00115744081966843	0.0251427146790663
GO:0044025	histone H2BS14 kinase activity	49/2411	245/18639	0.2	1.54616341766902	0.00115744081966843	0.0251427146790663
GO:0072354	histone H3T3 kinase activity	49/2411	245/18639	0.2	1.54616341766902	0.00115744081966843	0.0251427146790663
GO:0072371	histone H2AS121 kinase activity	49/2411	245/18639	0.2	1.54616341766902	0.00115744081966843	0.0251427146790663
GO:0072518	Rho-dependent protein serine/threonine kinase activity	49/2411	245/18639	0.2	1.54616341766902	0.00115744081966843	0.0251427146790663
GO:0140823	histone H2BS36 kinase activity	49/2411	245/18639	0.2	1.54616341766902	0.00115744081966843	0.0251427146790663
GO:0140855	histone H3S57 kinase activity	49/2411	245/18639	0.2	1.54616341766902	0.00115744081966843	0.0251427146790663
GO:0140995	histone H2A kinase activity	49/2411	245/18639	0.2	1.54616341766902	0.00115744081966843	0.0251427146790663
GO:0140997	histone H4 kinase activity	49/2411	245/18639	0.2	1.54616341766902	0.00115744081966843	0.0251427146790663
GO:0140998	histone H2B kinase activity	49/2411	245/18639	0.2	1.54616341766902	0.00115744081966843	0.0251427146790663
GO:1990244	histone H2AT120 kinase activity	49/2411	245/18639	0.2	1.54616341766902	0.00115744081966843	0.0251427146790663
GO:0070325	lipoprotein particle receptor binding	11/2411	31/18639	0.354838709677419	2.74319316038051	0.00116942858972401	0.0251427146790663
GO:0004677	DNA-dependent protein kinase activity	49/2411	246/18639	0.199186991869919	1.53987820052402	0.00126765671470564	0.0263754380962948
GO:0140857	histone H3T45 kinase activity	49/2411	246/18639	0.199186991869919	1.53987820052402	0.00126765671470564	0.0263754380962948
GO:0001217	DNA-binding transcription repressor activity	54/2411	278/18639	0.194244604316547	1.50166950636919	0.00135186313811248	0.0276810071137318
GO:0035403	histone H3T6 kinase activity	49/2411	247/18639	0.198380566801619	1.53364387582554	0.00138700665110603	0.0279568528113559
GO:0004222	metalloendopeptidase activity	26/2411	110/18639	0.236363636363636	1.82728403906338	0.00148022070801788	0.0287853027165941
GO:0030291	protein serine/threonine kinase inhibitor activity	14/2411	46/18639	0.304347826086957	2.35285737471372	0.00148477408933188	0.0287853027165941
GO:0031005	filamin binding	7/2411	15/18639	0.466666666666667	3.60771464122771	0.0014950506062107	0.0287853027165941
GO:0042562	hormone binding	23/2411	94/18639	0.24468085106383	1.89158290459507	0.00166479146173941	0.0314272243660263
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	52/2411	268/18639	0.194029850746269	1.5000092857983	0.00168099107074094	0.0314272243660263
GO:1901681	sulfur compound binding	53/2411	275/18639	0.192727272727273	1.48993929339014	0.00178040346367107	0.0328102924019382
GO:0003774	cytoskeletal motor activity	33/2411	153/18639	0.215686274509804	1.66743113670188	0.00197941837291766	0.035964080296673
GO:0046332	SMAD binding	20/2411	79/18639	0.253164556962025	1.95716888312534	0.00210475120642278	0.0365694591601189
GO:0008179	adenylate cyclase binding	6/2411	12/18639	0.5	3.86540854417254	0.00214080215934347	0.0365694591601189
GO:0017166	vinculin binding	6/2411	12/18639	0.5	3.86540854417254	0.00214080215934347	0.0365694591601189
GO:0031543	peptidyl-proline dioxygenase activity	6/2411	12/18639	0.5	3.86540854417254	0.00214080215934347	0.0365694591601189
GO:0005096	GTPase activator activity	52/2411	271/18639	0.191881918819188	1.48340401695182	0.00215447976447212	0.0365694591601189
GO:0005024	transforming growth factor beta receptor activity	7/2411	16/18639	0.4375	3.38223247615097	0.00236292101346297	0.0395865987969771
GO:0019955	cytokine binding	31/2411	144/18639	0.215277777777778	1.6642731231854	0.0027427943055645	0.0452673855695059
GO:0051287	NAD binding	15/2411	54/18639	0.277777777777778	2.14744919120697	0.00279850368607358	0.0452673855695059
GO:0001221	transcription coregulator binding	26/2411	115/18639	0.226086956521739	1.74783690693019	0.00287837061825082	0.0452673855695059
GO:0101005	deubiquitinase activity	26/2411	115/18639	0.226086956521739	1.74783690693019	0.00287837061825082	0.0452673855695059
GO:0030020	extracellular matrix structural constituent conferring tensile strength	13/2411	44/18639	0.295454545454545	2.28410504882923	0.0029043078601293	0.0452673855695059
GO:0015631	tubulin binding	69/2411	385/18639	0.179220779220779	1.38552306258652	0.0029125527149372	0.0452673855695059
GO:0019783	ubiquitin-like protein peptidase activity	28/2411	127/18639	0.220472440944882	1.70443211396585	0.0029934169491766	0.0459703317194978
GO:0008017	microtubule binding	52/2411	276/18639	0.188405797101449	1.45653075577516	0.00320371705260264	0.0478894087181599
GO:0031625	ubiquitin protein ligase binding	56/2411	302/18639	0.185430463576159	1.43352899651432	0.00327566455812518	0.0478894087181599
GO:0051020	GTPase binding	58/2411	315/18639	0.184126984126984	1.42345203531433	0.00329218864799081	0.0478894087181599
GO:0036122	BMP binding	8/2411	21/18639	0.380952380952381	2.94507317651241	0.00329838358225792	0.0478894087181599
GO:0051721	protein phosphatase 2A binding	10/2411	30/18639	0.333333333333333	2.57693902944836	0.00330399796582654	0.0478894087181599
GO:0070123	transforming growth factor beta receptor activity, type III	6/2411	13/18639	0.461538461538462	3.56806942539004	0.00354303866049617	0.050639778592703
GO:0004029	aldehyde dehydrogenase (NAD+) activity	7/2411	17/18639	0.411764705882353	3.18327762461268	0.00357226345111316	0.050639778592703
GO:0030695	GTPase regulator activity	84/2411	489/18639	0.171779141104294	1.32799311947032	0.00376611158215076	0.0528074341410269
GO:0042578	phosphoric ester hydrolase activity	65/2411	363/18639	0.179063360881543	1.38430609019953	0.00385644569032841	0.0534926337690715
GO:0043548	phosphatidylinositol 3-kinase binding	9/2411	26/18639	0.346153846153846	2.67605206904253	0.00393952050284364	0.0540636324326415
GO:0060589	nucleoside-triphosphatase regulator activity	84/2411	490/18639	0.171428571428571	1.32528292943059	0.00398263929502759	0.0540800493745852
GO:0005543	phospholipid binding	85/2411	497/18639	0.17102615694165	1.3221719366385	0.00404214683435311	0.0543163480866199
GO:0016791	phosphatase activity	51/2411	273/18639	0.186813186813187	1.44421857694359	0.00415805817719303	0.0552978870987526
GO:0004860	protein kinase inhibitor activity	20/2411	84/18639	0.238095238095238	1.84067073532026	0.00451920334278365	0.0594874725733766
GO:0000287	magnesium ion binding	44/2411	230/18639	0.191304347826087	1.47893892124863	0.00475922887869055	0.0620141944799071
GO:0004382	GDP phosphatase activity	5/2411	10/18639	0.5	3.86540854417254	0.00516804656301049	0.0657643450685539
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	7/2411	18/18639	0.388888888888889	3.00642886768976	0.00519997147053682	0.0657643450685539
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	7/2411	18/18639	0.388888888888889	3.00642886768976	0.00519997147053682	0.0657643450685539
GO:0008191	metalloendopeptidase inhibitor activity	6/2411	14/18639	0.428571428571429	3.31320732357646	0.00552745438117944	0.0685616937665527
GO:0042043	neurexin family protein binding	6/2411	14/18639	0.428571428571429	3.31320732357646	0.00552745438117944	0.0685616937665527
GO:0004857	enzyme inhibitor activity	72/2411	416/18639	0.173076923076923	1.33802603452126	0.00577479086895661	0.0709474306757527
GO:0017124	SH3 domain binding	25/2411	115/18639	0.217391304347826	1.6806124105098	0.00586501202435441	0.0713760897303508
GO:0004879	nuclear receptor activity	15/2411	59/18639	0.254237288135593	1.96546197161316	0.00691674446581766	0.0833887884196708
GO:0140416	transcription regulator inhibitor activity	10/2411	33/18639	0.303030303030303	2.34267184495306	0.00707959914640303	0.0845618786931473
GO:0060590	ATPase regulator activity	13/2411	49/18639	0.26530612244898	2.05103310507115	0.00792421114307435	0.0903367834632997
GO:0044325	transmembrane transporter binding	28/2411	136/18639	0.205882352941176	1.59163881230634	0.00806271243220595	0.0903367834632997
GO:0004714	transmembrane receptor protein tyrosine kinase activity	15/2411	60/18639	0.25	1.93270427208627	0.00814459385578366	0.0903367834632997
GO:0098531	ligand-modulated transcription factor activity	15/2411	60/18639	0.25	1.93270427208627	0.00814459385578366	0.0903367834632997
GO:0000774	adenyl-nucleotide exchange factor activity	6/2411	15/18639	0.4	3.09232683533803	0.00821572356449193	0.0903367834632997
GO:0045504	dynein heavy chain binding	6/2411	15/18639	0.4	3.09232683533803	0.00821572356449193	0.0903367834632997
GO:0044389	ubiquitin-like protein ligase binding	57/2411	322/18639	0.177018633540373	1.36849867712941	0.00822779619748334	0.0903367834632997
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	61/2411	349/18639	0.174785100286533	1.35123164008324	0.00846252994886585	0.0903367834632997
GO:0005536	D-glucose binding	5/2411	11/18639	0.454545454545455	3.51400776742958	0.00847345023182888	0.0903367834632997
GO:0032050	clathrin heavy chain binding	5/2411	11/18639	0.454545454545455	3.51400776742958	0.00847345023182888	0.0903367834632997
GO:0043522	leucine zipper domain binding	5/2411	11/18639	0.454545454545455	3.51400776742958	0.00847345023182888	0.0903367834632997
GO:0048185	activin binding	5/2411	11/18639	0.454545454545455	3.51400776742958	0.00847345023182888	0.0903367834632997
GO:0050998	nitric-oxide synthase binding	5/2411	11/18639	0.454545454545455	3.51400776742958	0.00847345023182888	0.0903367834632997
GO:0030165	PDZ domain binding	19/2411	83/18639	0.228915662650602	1.76970511660912	0.00864770158756688	0.0914388118685351
GO:0035091	phosphatidylinositol binding	51/2411	284/18639	0.179577464788732	1.38828053347042	0.00909745397601531	0.0954123221874776
GO:0019888	protein phosphatase regulator activity	23/2411	107/18639	0.214953271028037	1.66176442085922	0.00918412784481558	0.0955445558049363
GO:0019210	kinase inhibitor activity	20/2411	90/18639	0.222222222222222	1.71795935296557	0.0100547214946915	0.103764725825216
GO:0071949	FAD binding	11/2411	40/18639	0.275	2.1259746992949	0.0106383779149665	0.108916726272276
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	8/2411	25/18639	0.32	2.47386146827043	0.0109193946159208	0.110913535862503
GO:0005010	insulin-like growth factor receptor activity	13/2411	51/18639	0.254901960784314	1.97060043428404	0.0112398419932704	0.111237886563904
GO:0051082	unfolded protein binding	25/2411	121/18639	0.206611570247934	1.59727625792254	0.0113120904576568	0.111237886563904
GO:0035401	histone H3Y41 kinase activity	24/2411	115/18639	0.208695652173913	1.61338791408941	0.011412278008566	0.111237886563904
GO:0140801	histone H2AXY142 kinase activity	24/2411	115/18639	0.208695652173913	1.61338791408941	0.011412278008566	0.111237886563904
GO:0003777	microtubule motor activity	16/2411	68/18639	0.235294117647059	1.81901578549296	0.0116944427195239	0.111237886563904
GO:1990841	promoter-specific chromatin binding	16/2411	68/18639	0.235294117647059	1.81901578549296	0.0116944427195239	0.111237886563904
GO:0015385	sodium:proton antiporter activity	6/2411	16/18639	0.375	2.89905640812941	0.0117274050951093	0.111237886563904
GO:0030275	LRR domain binding	6/2411	16/18639	0.375	2.89905640812941	0.0117274050951093	0.111237886563904
GO:0070411	I-SMAD binding	6/2411	16/18639	0.375	2.89905640812941	0.0117274050951093	0.111237886563904
GO:0008237	metallopeptidase activity	35/2411	184/18639	0.190217391304348	1.47053585919608	0.0118720139195325	0.111787576322605
GO:0003714	transcription corepressor activity	38/2411	204/18639	0.186274509803922	1.44005416351526	0.0126233826697878	0.113282659904388
GO:0004725	protein tyrosine phosphatase activity	21/2411	98/18639	0.214285714285714	1.65660366178823	0.0128536561828062	0.113282659904388
GO:0140828	metal cation:monoatomic cation antiporter activity	11/2411	41/18639	0.268292682926829	2.07412165784868	0.0128800096882548	0.113282659904388
GO:0005025	transforming growth factor beta receptor activity, type I	5/2411	12/18639	0.416666666666667	3.22117378681045	0.0129967702836042	0.113282659904388
GO:0005026	transforming growth factor beta receptor activity, type II	5/2411	12/18639	0.416666666666667	3.22117378681045	0.0129967702836042	0.113282659904388
GO:0008603	cAMP-dependent protein kinase regulator activity	5/2411	12/18639	0.416666666666667	3.22117378681045	0.0129967702836042	0.113282659904388
GO:0016361	activin receptor activity, type I	5/2411	12/18639	0.416666666666667	3.22117378681045	0.0129967702836042	0.113282659904388
GO:0016362	activin receptor activity, type II	5/2411	12/18639	0.416666666666667	3.22117378681045	0.0129967702836042	0.113282659904388
GO:0017002	activin receptor activity	5/2411	12/18639	0.416666666666667	3.22117378681045	0.0129967702836042	0.113282659904388
GO:0035251	UDP-glucosyltransferase activity	5/2411	12/18639	0.416666666666667	3.22117378681045	0.0129967702836042	0.113282659904388
GO:0035259	nuclear glucocorticoid receptor binding	5/2411	12/18639	0.416666666666667	3.22117378681045	0.0129967702836042	0.113282659904388
GO:0005080	protein kinase C binding	13/2411	52/18639	0.25	1.93270427208627	0.0132565818548825	0.114771748944956
GO:0051010	microtubule plus-end binding	7/2411	21/18639	0.333333333333333	2.57693902944836	0.0134000588243897	0.115240505889752
GO:0019208	phosphatase regulator activity	24/2411	117/18639	0.205128205128205	1.58580863350668	0.0140426936234497	0.119967382610928
GO:0051018	protein kinase A binding	13/2411	53/18639	0.245283018867925	1.89623815374502	0.0155400973283602	0.131886352326214
GO:0000149	SNARE binding	22/2411	106/18639	0.207547169811321	1.60450920701502	0.0159252489718609	0.134271707017651
GO:0031072	heat shock protein binding	26/2411	131/18639	0.198473282442748	1.53436064348834	0.0164641244847619	0.137053100560143
GO:0043394	proteoglycan binding	10/2411	37/18639	0.27027027027027	2.08941002387705	0.0164676206099397	0.137053100560143
GO:0032266	phosphatidylinositol-3-phosphate binding	12/2411	48/18639	0.25	1.93270427208627	0.0169644698950153	0.14028311643955
GO:0004683	calcium/calmodulin-dependent protein kinase activity	8/2411	27/18639	0.296296296296296	2.29061247062077	0.0177185779624844	0.145585767972006
GO:0005172	vascular endothelial growth factor receptor binding	5/2411	13/18639	0.384615384615385	2.97339118782503	0.0189053525480467	0.152842251117243
GO:0039706	co-receptor binding	5/2411	13/18639	0.384615384615385	2.97339118782503	0.0189053525480467	0.152842251117243
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	14/2411	60/18639	0.233333333333333	1.80385732061385	0.0189571784331464	0.152842251117243
GO:0043531	ADP binding	10/2411	38/18639	0.263157894736842	2.0344255495645	0.0198274620533602	0.158866000303321
GO:0015085	calcium ion transmembrane transporter activity	28/2411	147/18639	0.19047619047619	1.47253658825621	0.0221825610389629	0.176638911976927
GO:0000295	adenine nucleotide transmembrane transporter activity	7/2411	23/18639	0.304347826086957	2.35285737471372	0.0224214970522975	0.177446203665422
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	78/2411	484/18639	0.161157024793388	1.24587548117958	0.0228378682443787	0.179639329483223
GO:0005006	epidermal growth factor receptor activity	12/2411	50/18639	0.24	1.85539610120282	0.0231892593269483	0.18129784564705
GO:0005548	phospholipid transporter activity	15/2411	68/18639	0.220588235294118	1.70532729889965	0.0252642102234795	0.196330308363184
GO:0005347	ATP transmembrane transporter activity	5/2411	14/18639	0.357142857142857	2.76100610298039	0.0263375181963062	0.198686540779152
GO:0008195	phosphatidate phosphatase activity	5/2411	14/18639	0.357142857142857	2.76100610298039	0.0263375181963062	0.198686540779152
GO:0042813	Wnt receptor activity	5/2411	14/18639	0.357142857142857	2.76100610298039	0.0263375181963062	0.198686540779152
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	5/2411	14/18639	0.357142857142857	2.76100610298039	0.0263375181963062	0.198686540779152
GO:0098821	BMP receptor activity	5/2411	14/18639	0.357142857142857	2.76100610298039	0.0263375181963062	0.198686540779152
GO:0099604	ligand-gated calcium channel activity	8/2411	29/18639	0.275862068965517	2.13263919678485	0.0271123227420262	0.203342420565197
GO:0016922	nuclear receptor binding	26/2411	137/18639	0.18978102189781	1.46716236713118	0.0278972571959442	0.20381044039858
GO:0061791	GTPase motor activity	10/2411	40/18639	0.25	1.93270427208627	0.0280028549459488	0.20381044039858
GO:1990606	membrane scission GTPase motor activity	10/2411	40/18639	0.25	1.93270427208627	0.0280028549459488	0.20381044039858
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	6/2411	19/18639	0.315789473684211	2.4413106594774	0.0282806735126711	0.20381044039858
GO:0005346	purine ribonucleotide transmembrane transporter activity	6/2411	19/18639	0.315789473684211	2.4413106594774	0.0282806735126711	0.20381044039858
GO:0031420	alkali metal ion binding	6/2411	19/18639	0.315789473684211	2.4413106594774	0.0282806735126711	0.20381044039858
GO:0042577	lipid phosphatase activity	6/2411	19/18639	0.315789473684211	2.4413106594774	0.0282806735126711	0.20381044039858
GO:0008013	beta-catenin binding	21/2411	106/18639	0.19811320754717	1.53157697033252	0.0294548101465875	0.211092806050544
GO:0004862	cAMP-dependent protein kinase inhibitor activity	4/2411	10/18639	0.4	3.09232683533803	0.0307502505291168	0.211583333306499
GO:0004935	adrenergic receptor activity	4/2411	10/18639	0.4	3.09232683533803	0.0307502505291168	0.211583333306499
GO:0005522	profilin binding	4/2411	10/18639	0.4	3.09232683533803	0.0307502505291168	0.211583333306499
GO:0008140	cAMP response element binding protein binding	4/2411	10/18639	0.4	3.09232683533803	0.0307502505291168	0.211583333306499
GO:0031996	thioesterase binding	4/2411	10/18639	0.4	3.09232683533803	0.0307502505291168	0.211583333306499
GO:0035374	chondroitin sulfate binding	4/2411	10/18639	0.4	3.09232683533803	0.0307502505291168	0.211583333306499
GO:0042975	peroxisome proliferator activated receptor binding	4/2411	10/18639	0.4	3.09232683533803	0.0307502505291168	0.211583333306499
GO:0001216	DNA-binding transcription activator activity	78/2411	491/18639	0.158859470468432	1.2281135089428	0.0308354005128851	0.211583333306499
GO:0140272	exogenous protein binding	17/2411	82/18639	0.207317073170732	1.60273037197398	0.0317069483471921	0.216412504591946
GO:0005319	lipid transporter activity	32/2411	178/18639	0.179775280898876	1.38980981363507	0.0327161001496327	0.219943810215349
GO:0001965	G-protein alpha-subunit binding	8/2411	30/18639	0.266666666666667	2.06155122355869	0.0329063219934592	0.219943810215349
GO:0015215	nucleotide transmembrane transporter activity	8/2411	30/18639	0.266666666666667	2.06155122355869	0.0329063219934592	0.219943810215349
GO:0035925	mRNA 3'-UTR AU-rich region binding	8/2411	30/18639	0.266666666666667	2.06155122355869	0.0329063219934592	0.219943810215349
GO:1901981	phosphatidylinositol phosphate binding	33/2411	185/18639	0.178378378378378	1.37901061575885	0.0336714614142689	0.223897861981479
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	18/2411	89/18639	0.202247191011236	1.56353604033946	0.0346283745655764	0.226444188168487
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	18/2411	89/18639	0.202247191011236	1.56353604033946	0.0346283745655764	0.226444188168487
GO:0004709	MAP kinase kinase kinase activity	7/2411	25/18639	0.28	2.16462878473662	0.0349392461117275	0.226444188168487
GO:0005523	tropomyosin binding	5/2411	15/18639	0.333333333333333	2.57693902944836	0.0353984155122135	0.226444188168487
GO:0005003	ephrin receptor activity	12/2411	53/18639	0.226415094339623	1.75037368038002	0.0354587023333599	0.226444188168487
GO:0005005	transmembrane-ephrin receptor activity	12/2411	53/18639	0.226415094339623	1.75037368038002	0.0354587023333599	0.226444188168487
GO:0005246	calcium channel regulator activity	12/2411	53/18639	0.226415094339623	1.75037368038002	0.0354587023333599	0.226444188168487
GO:0038064	collagen receptor activity	12/2411	53/18639	0.226415094339623	1.75037368038002	0.0354587023333599	0.226444188168487
GO:0030246	carbohydrate binding	47/2411	280/18639	0.167857142857143	1.29767286840078	0.0359403699882148	0.228389543274863
GO:0045505	dynein intermediate chain binding	9/2411	36/18639	0.25	1.93270427208627	0.0361583465236407	0.228648367723022
GO:0140030	modification-dependent protein binding	31/2411	173/18639	0.179190751445087	1.38529092334507	0.0365111666807858	0.229753195210798
GO:0099106	ion channel regulator activity	29/2411	160/18639	0.18125	1.40121059726255	0.0368393545232068	0.230693045315227
GO:0140793	histone H2AXY142 phosphatase activity	18/2411	90/18639	0.2	1.54616341766902	0.038238813167757	0.237686466369025
GO:0051879	Hsp90 protein binding	10/2411	42/18639	0.238095238095238	1.84067073532026	0.0383246395385715	0.237686466369025
GO:0017147	Wnt-protein binding	8/2411	31/18639	0.258064516129032	1.99504957118583	0.0394878184551098	0.241067918037774
GO:0016879	ligase activity, forming carbon-nitrogen bonds	11/2411	48/18639	0.229166666666667	1.77164558274575	0.0396762875243848	0.241067918037774
GO:0019887	protein kinase regulator activity	43/2411	255/18639	0.168627450980392	1.30362797960329	0.04049914358946	0.241067918037774
GO:0016247	channel regulator activity	30/2411	168/18639	0.178571428571429	1.38050305149019	0.0407531532995754	0.241067918037774
GO:0005160	transforming growth factor beta receptor binding	7/2411	26/18639	0.269230769230769	2.08137383147752	0.042645761720322	0.241067918037774
GO:0005227	calcium-activated cation channel activity	7/2411	26/18639	0.269230769230769	2.08137383147752	0.042645761720322	0.241067918037774
GO:0015216	purine nucleotide transmembrane transporter activity	7/2411	26/18639	0.269230769230769	2.08137383147752	0.042645761720322	0.241067918037774
GO:0030507	spectrin binding	7/2411	26/18639	0.269230769230769	2.08137383147752	0.042645761720322	0.241067918037774
GO:0050750	low-density lipoprotein particle receptor binding	7/2411	26/18639	0.269230769230769	2.08137383147752	0.042645761720322	0.241067918037774
GO:0051139	metal cation:proton antiporter activity	7/2411	26/18639	0.269230769230769	2.08137383147752	0.042645761720322	0.241067918037774
GO:0140789	histone phosphatase activity	25/2411	136/18639	0.183823529411765	1.42110608241638	0.0430270587137591	0.241067918037774
GO:0002162	dystroglycan binding	4/2411	11/18639	0.363636363636364	2.81120621394367	0.0434798506989956	0.241067918037774
GO:0003953	NAD+ nucleosidase activity	4/2411	11/18639	0.363636363636364	2.81120621394367	0.0434798506989956	0.241067918037774
GO:0004016	adenylate cyclase activity	4/2411	11/18639	0.363636363636364	2.81120621394367	0.0434798506989956	0.241067918037774
GO:0008526	phosphatidylinositol transfer activity	4/2411	11/18639	0.363636363636364	2.81120621394367	0.0434798506989956	0.241067918037774
GO:0034056	estrogen response element binding	4/2411	11/18639	0.363636363636364	2.81120621394367	0.0434798506989956	0.241067918037774
GO:0048407	platelet-derived growth factor binding	4/2411	11/18639	0.363636363636364	2.81120621394367	0.0434798506989956	0.241067918037774
GO:0070697	activin receptor binding	4/2411	11/18639	0.363636363636364	2.81120621394367	0.0434798506989956	0.241067918037774
GO:0140031	phosphorylation-dependent protein binding	4/2411	11/18639	0.363636363636364	2.81120621394367	0.0434798506989956	0.241067918037774
GO:0140537	transcription regulator activator activity	4/2411	11/18639	0.363636363636364	2.81120621394367	0.0434798506989956	0.241067918037774
GO:0180030	inositol phosphate kinase activity	4/2411	11/18639	0.363636363636364	2.81120621394367	0.0434798506989956	0.241067918037774
GO:0005245	voltage-gated calcium channel activity	10/2411	43/18639	0.232558139534884	1.79786443915002	0.0443582081989618	0.241067918037774
GO:0048156	tau protein binding	10/2411	43/18639	0.232558139534884	1.79786443915002	0.0443582081989618	0.241067918037774
GO:0019200	carbohydrate kinase activity	6/2411	21/18639	0.285714285714286	2.20880488238431	0.0451816232493788	0.241067918037774
GO:0005004	GPI-linked ephrin receptor activity	11/2411	49/18639	0.224489795918367	1.73548955044482	0.0454020312085222	0.241067918037774
GO:0005008	hepatocyte growth factor receptor activity	11/2411	49/18639	0.224489795918367	1.73548955044482	0.0454020312085222	0.241067918037774
GO:0005009	insulin receptor activity	11/2411	49/18639	0.224489795918367	1.73548955044482	0.0454020312085222	0.241067918037774
GO:0005011	macrophage colony-stimulating factor receptor activity	11/2411	49/18639	0.224489795918367	1.73548955044482	0.0454020312085222	0.241067918037774
GO:0005018	platelet-derived growth factor alpha-receptor activity	11/2411	49/18639	0.224489795918367	1.73548955044482	0.0454020312085222	0.241067918037774
GO:0005020	stem cell factor receptor activity	11/2411	49/18639	0.224489795918367	1.73548955044482	0.0454020312085222	0.241067918037774
GO:0008288	boss receptor activity	11/2411	49/18639	0.224489795918367	1.73548955044482	0.0454020312085222	0.241067918037774
GO:0036332	placental growth factor receptor activity	11/2411	49/18639	0.224489795918367	1.73548955044482	0.0454020312085222	0.241067918037774
GO:0038062	protein tyrosine kinase collagen receptor activity	11/2411	49/18639	0.224489795918367	1.73548955044482	0.0454020312085222	0.241067918037774
GO:0060175	brain-derived neurotrophic factor receptor activity	11/2411	49/18639	0.224489795918367	1.73548955044482	0.0454020312085222	0.241067918037774
GO:0019905	syntaxin binding	13/2411	61/18639	0.213114754098361	1.64755118276207	0.0458179124322729	0.241067918037774
GO:1902936	phosphatidylinositol bisphosphate binding	21/2411	111/18639	0.189189189189189	1.46258701671394	0.0459686101797616	0.241067918037774
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	5/2411	16/18639	0.3125	2.41588034010784	0.0461579657018063	0.241067918037774
GO:0016722	oxidoreductase activity, acting on metal ions	5/2411	16/18639	0.3125	2.41588034010784	0.0461579657018063	0.241067918037774
GO:0140327	flippase activity	5/2411	16/18639	0.3125	2.41588034010784	0.0461579657018063	0.241067918037774
GO:0141108	transporter regulator activity	30/2411	170/18639	0.176470588235294	1.36426183911972	0.0466690348553716	0.242754253884796
GO:0005262	calcium channel activity	24/2411	131/18639	0.183206106870229	1.41633290168154	0.0482597934325129	0.250020616578079
GO:0001046	core promoter sequence-specific DNA binding	10/2411	44/18639	0.227272727272727	1.75700388371479	0.0510036707139334	0.262130419207068
GO:0001223	transcription coactivator binding	10/2411	44/18639	0.227272727272727	1.75700388371479	0.0510036707139334	0.262130419207068
GO:0005007	fibroblast growth factor receptor activity	11/2411	50/18639	0.22	1.70077975943592	0.0516671719956328	0.262404141237663
GO:0005017	platelet-derived growth factor receptor activity	11/2411	50/18639	0.22	1.70077975943592	0.0516671719956328	0.262404141237663
GO:0005019	platelet-derived growth factor beta-receptor activity	11/2411	50/18639	0.22	1.70077975943592	0.0516671719956328	0.262404141237663
GO:0001618	virus receptor activity	16/2411	81/18639	0.197530864197531	1.52707498041384	0.0537161136581421	0.271740339682366
GO:0033218	amide binding	41/2411	247/18639	0.165991902834008	1.28325303895607	0.0549259761490728	0.276559638456818
GO:0044183	protein folding chaperone	15/2411	75/18639	0.2	1.54616341766902	0.0550975403747305	0.276559638456818
GO:0016881	acid-amino acid ligase activity	6/2411	22/18639	0.272727272727273	2.10840466045775	0.0555601783577889	0.276728301473157
GO:0030021	extracellular matrix structural constituent conferring compression resistance	6/2411	22/18639	0.272727272727273	2.10840466045775	0.0555601783577889	0.276728301473157
GO:0016776	phosphotransferase activity, phosphate group as acceptor	9/2411	39/18639	0.230769230769231	1.78403471269502	0.0572773968847343	0.282651471155343
GO:0140303	intramembrane lipid transporter activity	10/2411	45/18639	0.222222222222222	1.71795935296557	0.0582792536718218	0.282651471155343
GO:0005021	vascular endothelial growth factor receptor activity	11/2411	51/18639	0.215686274509804	1.66743113670188	0.058487493435902	0.282651471155343
GO:0005030	neurotrophin receptor activity	11/2411	51/18639	0.215686274509804	1.66743113670188	0.058487493435902	0.282651471155343
GO:0017110	nucleoside diphosphate phosphatase activity	5/2411	17/18639	0.294117647058824	2.2737697318662	0.0586505913385368	0.282651471155343
GO:0048038	quinone binding	5/2411	17/18639	0.294117647058824	2.2737697318662	0.0586505913385368	0.282651471155343
GO:0005527	macrolide binding	4/2411	12/18639	0.333333333333333	2.57693902944836	0.0587213909066913	0.282651471155343
GO:0015269	calcium-activated potassium channel activity	4/2411	12/18639	0.333333333333333	2.57693902944836	0.0587213909066913	0.282651471155343
GO:0035197	siRNA binding	4/2411	12/18639	0.333333333333333	2.57693902944836	0.0587213909066913	0.282651471155343
GO:0051087	protein-folding chaperone binding	24/2411	134/18639	0.17910447761194	1.38462395612151	0.0601855260611103	0.288622039475213
GO:0004867	serine-type endopeptidase inhibitor activity	18/2411	95/18639	0.189473684210526	1.46478639568644	0.0604608313399546	0.288868416402005
GO:0042277	peptide binding	41/2411	249/18639	0.164658634538153	1.27294578563112	0.0609505444261703	0.288896900122894
GO:0051019	mitogen-activated protein kinase binding	7/2411	28/18639	0.25	1.93270427208627	0.0611386463050776	0.288896900122894
GO:0051959	dynein light intermediate chain binding	7/2411	28/18639	0.25	1.93270427208627	0.0611386463050776	0.288896900122894
GO:0004721	phosphoprotein phosphatase activity	30/2411	175/18639	0.171428571428571	1.32528292943059	0.0641850504845275	0.301460996218089
GO:0008376	acetylgalactosaminyltransferase activity	8/2411	34/18639	0.235294117647059	1.81901578549296	0.0642649410542437	0.301460996218089
GO:0001540	amyloid-beta binding	16/2411	83/18639	0.192771084337349	1.49027799293399	0.0647389671353856	0.302584302915389
GO:0008083	growth factor activity	28/2411	162/18639	0.172839506172839	1.33619060786211	0.0660084408017216	0.307184189502817
GO:0030276	clathrin binding	10/2411	46/18639	0.217391304347826	1.6806124105098	0.0661993834742505	0.307184189502817
GO:0005158	insulin receptor binding	6/2411	23/18639	0.260869565217391	2.01673489261176	0.067256183524433	0.307417972698708
GO:0017134	fibroblast growth factor binding	6/2411	23/18639	0.260869565217391	2.01673489261176	0.067256183524433	0.307417972698708
GO:0031681	G-protein beta-subunit binding	6/2411	23/18639	0.260869565217391	2.01673489261176	0.067256183524433	0.307417972698708
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	6/2411	23/18639	0.260869565217391	2.01673489261176	0.067256183524433	0.307417972698708
GO:0035591	signaling adaptor activity	23/2411	129/18639	0.178294573643411	1.37836273668168	0.0674413071889414	0.307417972698708
GO:0002020	protease binding	24/2411	136/18639	0.176470588235294	1.36426183911972	0.069205570059079	0.314349244282436
GO:0120013	lipid transfer activity	13/2411	65/18639	0.2	1.54616341766902	0.0707584948418729	0.320275292442162
GO:0019207	kinase regulator activity	46/2411	287/18639	0.160278745644599	1.23908566572778	0.07182019913312	0.321953922021395
GO:0000900	mRNA regulatory element binding translation repressor activity	5/2411	18/18639	0.277777777777778	2.14744919120697	0.0728763916513546	0.321953922021395
GO:0004706	JUN kinase kinase kinase activity	5/2411	18/18639	0.277777777777778	2.14744919120697	0.0728763916513546	0.321953922021395
GO:0004970	glutamate-gated receptor activity	5/2411	18/18639	0.277777777777778	2.14744919120697	0.0728763916513546	0.321953922021395
GO:0031690	adrenergic receptor binding	5/2411	18/18639	0.277777777777778	2.14744919120697	0.0728763916513546	0.321953922021395
GO:0070064	proline-rich region binding	5/2411	18/18639	0.277777777777778	2.14744919120697	0.0728763916513546	0.321953922021395
GO:0070628	proteasome binding	5/2411	18/18639	0.277777777777778	2.14744919120697	0.0728763916513546	0.321953922021395
GO:0046873	metal ion transmembrane transporter activity	69/2411	450/18639	0.153333333333333	1.18539195354625	0.0740511277544328	0.326027149499038
GO:0017080	sodium channel regulator activity	9/2411	41/18639	0.219512195121951	1.69700862914892	0.0750282508193517	0.329205590329809
GO:0019855	calcium channel inhibitor activity	4/2411	13/18639	0.307692307692308	2.37871295026003	0.0764174079549777	0.330800188798393
GO:0030955	potassium ion binding	4/2411	13/18639	0.307692307692308	2.37871295026003	0.0764174079549777	0.330800188798393
GO:0043560	insulin receptor substrate binding	4/2411	13/18639	0.307692307692308	2.37871295026003	0.0764174079549777	0.330800188798393
GO:1901338	catecholamine binding	4/2411	13/18639	0.307692307692308	2.37871295026003	0.0764174079549777	0.330800188798393
GO:0003924	GTPase activity	52/2411	331/18639	0.157099697885196	1.21450902898473	0.078274447022617	0.337705808224669
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	6/2411	24/18639	0.25	1.93270427208627	0.08027034880161	0.340620888006832
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	6/2411	24/18639	0.25	1.93270427208627	0.08027034880161	0.340620888006832
GO:0005540	hyaluronic acid binding	6/2411	24/18639	0.25	1.93270427208627	0.08027034880161	0.340620888006832
GO:0070300	phosphatidic acid binding	6/2411	24/18639	0.25	1.93270427208627	0.08027034880161	0.340620888006832
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	6/2411	24/18639	0.25	1.93270427208627	0.08027034880161	0.340620888006832
GO:0140463	chromatin-protein adaptor activity	11/2411	54/18639	0.203703703703704	1.57479607355178	0.0823934648098282	0.348483834769437
GO:0022839	monoatomic ion-gated channel activity	7/2411	30/18639	0.233333333333333	1.80385732061385	0.0838526895703544	0.351709455041246
GO:0031624	ubiquitin conjugating enzyme binding	7/2411	30/18639	0.233333333333333	1.80385732061385	0.0838526895703544	0.351709455041246
GO:0050660	flavin adenine dinucleotide binding	16/2411	86/18639	0.186046511627907	1.43829155132002	0.0839740404284525	0.351709455041246
GO:0030295	protein kinase activator activity	24/2411	139/18639	0.172661870503597	1.33481733899483	0.0844152760248329	0.352413288259011
GO:0019894	kinesin binding	9/2411	42/18639	0.214285714285714	1.65660366178823	0.085038326623201	0.353219486016768
GO:0044390	ubiquitin-like protein conjugating enzyme binding	8/2411	36/18639	0.222222222222222	1.71795935296557	0.0851560156210967	0.353219486016768
GO:0003713	transcription coactivator activity	41/2411	256/18639	0.16015625	1.23813867430527	0.0857853528854918	0.354527855193828
GO:0016500	protein-hormone receptor activity	13/2411	67/18639	0.194029850746269	1.5000092857983	0.0860210997485799	0.354527855193828
GO:0008234	cysteine-type peptidase activity	31/2411	187/18639	0.165775401069519	1.2815793034155	0.0866278524968176	0.355891495926416
GO:0008574	plus-end-directed microtubule motor activity	5/2411	19/18639	0.263157894736842	2.0344255495645	0.0888034338437417	0.358223486964783
GO:0043395	heparan sulfate proteoglycan binding	5/2411	19/18639	0.263157894736842	2.0344255495645	0.0888034338437417	0.358223486964783
GO:0046527	glucosyltransferase activity	5/2411	19/18639	0.263157894736842	2.0344255495645	0.0888034338437417	0.358223486964783
GO:0046624	sphingolipid transporter activity	5/2411	19/18639	0.263157894736842	2.0344255495645	0.0888034338437417	0.358223486964783
GO:1990380	K48-linked deubiquitinase activity	5/2411	19/18639	0.263157894736842	2.0344255495645	0.0888034338437417	0.358223486964783
GO:0015026	coreceptor activity	12/2411	61/18639	0.19672131147541	1.52081647639575	0.0888616401773106	0.358223486964783
GO:0043130	ubiquitin binding	18/2411	100/18639	0.18	1.39154707590212	0.0902837899855363	0.36282270741851
GO:0032182	ubiquitin-like protein binding	21/2411	120/18639	0.175	1.35289299046039	0.090821924990805	0.363851811298567
GO:0005525	GTP binding	58/2411	378/18639	0.153439153439153	1.18621002942861	0.0934474655623096	0.368105560288153
GO:0004866	endopeptidase inhibitor activity	27/2411	161/18639	0.167701863354037	1.2964724309647	0.0934867072331016	0.368105560288153
GO:0035254	glutamate receptor binding	10/2411	49/18639	0.204081632653061	1.57771777313165	0.0939105556701571	0.368105560288153
GO:0008139	nuclear localization sequence binding	6/2411	25/18639	0.24	1.85539610120282	0.0945854338615729	0.368105560288153
GO:0042974	nuclear retinoic acid receptor binding	6/2411	25/18639	0.24	1.85539610120282	0.0945854338615729	0.368105560288153
GO:0047617	fatty acyl-CoA hydrolase activity	6/2411	25/18639	0.24	1.85539610120282	0.0945854338615729	0.368105560288153
GO:0019001	guanyl nucleotide binding	61/2411	400/18639	0.1525	1.17894960597263	0.0955096327643751	0.368105560288153
GO:0032561	guanyl ribonucleotide binding	61/2411	400/18639	0.1525	1.17894960597263	0.0955096327643751	0.368105560288153
GO:0005545	1-phosphatidylinositol binding	4/2411	14/18639	0.285714285714286	2.20880488238431	0.0964493638584464	0.368105560288153
GO:0008174	mRNA methyltransferase activity	4/2411	14/18639	0.285714285714286	2.20880488238431	0.0964493638584464	0.368105560288153
GO:0008474	palmitoyl-(protein) hydrolase activity	4/2411	14/18639	0.285714285714286	2.20880488238431	0.0964493638584464	0.368105560288153
GO:0030983	mismatched DNA binding	4/2411	14/18639	0.285714285714286	2.20880488238431	0.0964493638584464	0.368105560288153
GO:0070742	C2H2 zinc finger domain binding	4/2411	14/18639	0.285714285714286	2.20880488238431	0.0964493638584464	0.368105560288153
GO:0098599	palmitoyl hydrolase activity	4/2411	14/18639	0.285714285714286	2.20880488238431	0.0964493638584464	0.368105560288153
GO:1901474	azole transmembrane transporter activity	4/2411	14/18639	0.285714285714286	2.20880488238431	0.0964493638584464	0.368105560288153
GO:1990825	sequence-specific mRNA binding	4/2411	14/18639	0.285714285714286	2.20880488238431	0.0964493638584464	0.368105560288153
GO:0070273	phosphatidylinositol-4-phosphate binding	7/2411	31/18639	0.225806451612903	1.7456683747876	0.096792443645634	0.368325228032059
GO:0031490	chromatin DNA binding	22/2411	128/18639	0.171875	1.32873418705931	0.0988648793426682	0.375104983388359
GO:0030414	peptidase inhibitor activity	28/2411	169/18639	0.165680473372781	1.2808454347554	0.0997958357132848	0.377526768534127
GO:0015171	amino acid transmembrane transporter activity	18/2411	102/18639	0.176470588235294	1.36426183911972	0.104470165041947	0.394054131298572
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	5/2411	20/18639	0.25	1.93270427208627	0.106370853034719	0.400053645524161
GO:0016248	channel inhibitor activity	9/2411	44/18639	0.204545454545455	1.58130349534331	0.10732734477802	0.40126498483685
GO:0016790	thiolester hydrolase activity	9/2411	44/18639	0.204545454545455	1.58130349534331	0.10732734477802	0.40126498483685
GO:0017022	myosin binding	14/2411	76/18639	0.184210526315789	1.42409788469515	0.107721406333819	0.40126498483685
GO:0022843	voltage-gated monoatomic cation channel activity	24/2411	143/18639	0.167832167832168	1.29747979105092	0.107937170339835	0.40126498483685
GO:0004112	cyclic-nucleotide phosphodiesterase activity	6/2411	26/18639	0.230769230769231	1.78403471269502	0.110167335503948	0.403738246591174
GO:0004435	phosphatidylinositol phospholipase C activity	6/2411	26/18639	0.230769230769231	1.78403471269502	0.110167335503948	0.403738246591174
GO:0016289	acyl-CoA hydrolase activity	6/2411	26/18639	0.230769230769231	1.78403471269502	0.110167335503948	0.403738246591174
GO:0070006	metalloaminopeptidase activity	6/2411	26/18639	0.230769230769231	1.78403471269502	0.110167335503948	0.403738246591174
GO:0120014	phospholipid transfer activity	6/2411	26/18639	0.230769230769231	1.78403471269502	0.110167335503948	0.403738246591174
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	15/2411	83/18639	0.180722891566265	1.39713561837562	0.11156168295452	0.40704488425608
GO:0008514	organic anion transmembrane transporter activity	42/2411	269/18639	0.156133828996283	1.20704207327321	0.111700689167948	0.40704488425608
GO:0016782	transferase activity, transferring sulphur-containing groups	13/2411	70/18639	0.185714285714286	1.4357231735498	0.112505425318642	0.408822531439573
GO:0005048	signal sequence binding	10/2411	51/18639	0.196078431372549	1.5158464879108	0.115686988943151	0.419202853192878
GO:0047372	monoacylglycerol lipase activity	4/2411	15/18639	0.266666666666667	2.06155122355869	0.118649708711622	0.426345749966552
GO:0120283	protein serine/threonine kinase binding	4/2411	15/18639	0.266666666666667	2.06155122355869	0.118649708711622	0.426345749966552
GO:0140776	protein-containing complex destabilizing activity	4/2411	15/18639	0.266666666666667	2.06155122355869	0.118649708711622	0.426345749966552
GO:0141110	transporter inhibitor activity	9/2411	45/18639	0.2	1.54616341766902	0.119589367554569	0.42852856707054
GO:0005244	voltage-gated monoatomic ion channel activity	28/2411	173/18639	0.161849710982659	1.25123051140845	0.123416170384796	0.434132707643394
GO:0005248	voltage-gated sodium channel activity	5/2411	21/18639	0.238095238095238	1.84067073532026	0.125492487342638	0.434132707643394
GO:0010314	phosphatidylinositol-5-phosphate binding	5/2411	21/18639	0.238095238095238	1.84067073532026	0.125492487342638	0.434132707643394
GO:0051428	peptide hormone receptor binding	5/2411	21/18639	0.238095238095238	1.84067073532026	0.125492487342638	0.434132707643394
GO:0035255	ionotropic glutamate receptor binding	6/2411	27/18639	0.222222222222222	1.71795935296557	0.126966495352058	0.434132707643394
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	6/2411	27/18639	0.222222222222222	1.71795935296557	0.126966495352058	0.434132707643394
GO:0030159	signaling receptor complex adaptor activity	10/2411	52/18639	0.192307692307692	1.48669559391252	0.127546768342249	0.434132707643394
GO:0160215	deacylase activity	12/2411	65/18639	0.184615384615385	1.42722777015602	0.12799935048941	0.434132707643394
GO:0005528	FK506 binding	3/2411	10/18639	0.3	2.31924512650353	0.12923020134501	0.434132707643394
GO:0015187	glycine transmembrane transporter activity	3/2411	10/18639	0.3	2.31924512650353	0.12923020134501	0.434132707643394
GO:0015643	toxic substance binding	3/2411	10/18639	0.3	2.31924512650353	0.12923020134501	0.434132707643394
GO:0015658	branched-chain amino acid transmembrane transporter activity	3/2411	10/18639	0.3	2.31924512650353	0.12923020134501	0.434132707643394
GO:0016427	tRNA (cytidine) methyltransferase activity	3/2411	10/18639	0.3	2.31924512650353	0.12923020134501	0.434132707643394
GO:0016868	intramolecular phosphotransferase activity	3/2411	10/18639	0.3	2.31924512650353	0.12923020134501	0.434132707643394
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	3/2411	10/18639	0.3	2.31924512650353	0.12923020134501	0.434132707643394
GO:0031957	very long-chain fatty acid-CoA ligase activity	3/2411	10/18639	0.3	2.31924512650353	0.12923020134501	0.434132707643394
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	3/2411	10/18639	0.3	2.31924512650353	0.12923020134501	0.434132707643394
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	3/2411	10/18639	0.3	2.31924512650353	0.12923020134501	0.434132707643394
GO:0043121	neurotrophin binding	3/2411	10/18639	0.3	2.31924512650353	0.12923020134501	0.434132707643394
GO:0070097	delta-catenin binding	3/2411	10/18639	0.3	2.31924512650353	0.12923020134501	0.434132707643394
GO:0070513	death domain binding	3/2411	10/18639	0.3	2.31924512650353	0.12923020134501	0.434132707643394
GO:0070739	protein-glutamic acid ligase activity	3/2411	10/18639	0.3	2.31924512650353	0.12923020134501	0.434132707643394
GO:0070740	tubulin-glutamic acid ligase activity	3/2411	10/18639	0.3	2.31924512650353	0.12923020134501	0.434132707643394
GO:1990763	arrestin family protein binding	3/2411	10/18639	0.3	2.31924512650353	0.12923020134501	0.434132707643394
GO:0052689	carboxylic ester hydrolase activity	16/2411	92/18639	0.173913043478261	1.34448992840784	0.132493030926989	0.443937688041081
GO:0031593	polyubiquitin modification-dependent protein binding	11/2411	59/18639	0.186440677966102	1.44133877918298	0.133926482630442	0.447578141433341
GO:0022832	voltage-gated channel activity	28/2411	175/18639	0.16	1.23693073413521	0.136418237868164	0.454727459560547
GO:0008146	sulfotransferase activity	10/2411	53/18639	0.188679245283019	1.45864473365002	0.14003617297289	0.462888376211591
GO:0017046	peptide hormone binding	10/2411	53/18639	0.188679245283019	1.45864473365002	0.14003617297289	0.462888376211591
GO:0140296	general transcription initiation factor binding	10/2411	53/18639	0.188679245283019	1.45864473365002	0.14003617297289	0.462888376211591
GO:0051427	hormone receptor binding	7/2411	34/18639	0.205882352941176	1.59163881230634	0.141677712071547	0.462888376211591
GO:0051213	dioxygenase activity	16/2411	93/18639	0.172043010752688	1.33003304745722	0.14187642372194	0.462888376211591
GO:0051219	phosphoprotein binding	16/2411	93/18639	0.172043010752688	1.33003304745722	0.14187642372194	0.462888376211591
GO:0019209	kinase activator activity	24/2411	148/18639	0.162162162162162	1.25364601432623	0.142634102456034	0.462888376211591
GO:0004708	MAP kinase kinase activity	4/2411	16/18639	0.25	1.93270427208627	0.142813623048227	0.462888376211591
GO:0008142	oxysterol binding	4/2411	16/18639	0.25	1.93270427208627	0.142813623048227	0.462888376211591
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	4/2411	16/18639	0.25	1.93270427208627	0.142813623048227	0.462888376211591
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	4/2411	16/18639	0.25	1.93270427208627	0.142813623048227	0.462888376211591
GO:0050698	proteoglycan sulfotransferase activity	6/2411	28/18639	0.214285714285714	1.65660366178823	0.144919545092143	0.465725697483097
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	6/2411	28/18639	0.214285714285714	1.65660366178823	0.144919545092143	0.465725697483097
GO:0141052	histone H3 demethylase activity	6/2411	28/18639	0.214285714285714	1.65660366178823	0.144919545092143	0.465725697483097
GO:0042393	histone binding	38/2411	247/18639	0.153846153846154	1.18935647513001	0.145133124331942	0.465725697483097
GO:0031683	G-protein beta/gamma-subunit complex binding	5/2411	22/18639	0.227272727272727	1.75700388371479	0.146060813514652	0.467539576759059
GO:0005261	monoatomic cation channel activity	51/2411	341/18639	0.149560117302053	1.15622191057361	0.149194965265496	0.476295882196393
GO:0015297	antiporter activity	22/2411	135/18639	0.162962962962963	1.25983685884142	0.149534753712821	0.476295882196393
GO:0061650	ubiquitin-like protein conjugating enzyme activity	8/2411	41/18639	0.195121951219512	1.50845211479904	0.152501155438573	0.480805292979384
GO:0003925	G protein activity	10/2411	54/18639	0.185185185185185	1.43163279413798	0.153136788464494	0.480805292979384
GO:0035064	methylated histone binding	13/2411	74/18639	0.175675675675676	1.35811651552008	0.154416510261937	0.480805292979384
GO:0033192	calmodulin-dependent protein phosphatase activity	14/2411	81/18639	0.172839506172839	1.33619060786211	0.157425350018028	0.480805292979384
GO:0140791	histone H2AXS140 phosphatase activity	14/2411	81/18639	0.172839506172839	1.33619060786211	0.157425350018028	0.480805292979384
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	14/2411	81/18639	0.172839506172839	1.33619060786211	0.157425350018028	0.480805292979384
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	14/2411	81/18639	0.172839506172839	1.33619060786211	0.157425350018028	0.480805292979384
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	14/2411	81/18639	0.172839506172839	1.33619060786211	0.157425350018028	0.480805292979384
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	14/2411	81/18639	0.172839506172839	1.33619060786211	0.157425350018028	0.480805292979384
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	14/2411	81/18639	0.172839506172839	1.33619060786211	0.157425350018028	0.480805292979384
GO:1990439	MAP kinase serine/threonine phosphatase activity	14/2411	81/18639	0.172839506172839	1.33619060786211	0.157425350018028	0.480805292979384
GO:0015081	sodium ion transmembrane transporter activity	26/2411	164/18639	0.158536585365854	1.22561734327422	0.157965268054461	0.480805292979384
GO:0016836	hydro-lyase activity	11/2411	61/18639	0.180327868852459	1.39408177002944	0.158502087296007	0.480805292979384
GO:0061631	ubiquitin conjugating enzyme activity	7/2411	35/18639	0.2	1.54616341766902	0.158530228911796	0.480805292979384
GO:0140693	molecular condensate scaffold activity	9/2411	48/18639	0.1875	1.4495282040647	0.160632547760882	0.480805292979384
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	3/2411	11/18639	0.272727272727273	2.10840466045775	0.161386582837266	0.480805292979384
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	3/2411	11/18639	0.272727272727273	2.10840466045775	0.161386582837266	0.480805292979384
GO:0005114	type II transforming growth factor beta receptor binding	3/2411	11/18639	0.272727272727273	2.10840466045775	0.161386582837266	0.480805292979384
GO:0005225	volume-sensitive anion channel activity	3/2411	11/18639	0.272727272727273	2.10840466045775	0.161386582837266	0.480805292979384
GO:0008432	JUN kinase binding	3/2411	11/18639	0.272727272727273	2.10840466045775	0.161386582837266	0.480805292979384
GO:0010854	adenylate cyclase regulator activity	3/2411	11/18639	0.272727272727273	2.10840466045775	0.161386582837266	0.480805292979384
GO:0015173	aromatic amino acid transmembrane transporter activity	3/2411	11/18639	0.272727272727273	2.10840466045775	0.161386582837266	0.480805292979384
GO:0015217	ADP transmembrane transporter activity	3/2411	11/18639	0.272727272727273	2.10840466045775	0.161386582837266	0.480805292979384
GO:0016176	superoxide-generating NADPH oxidase activator activity	3/2411	11/18639	0.272727272727273	2.10840466045775	0.161386582837266	0.480805292979384
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	3/2411	11/18639	0.272727272727273	2.10840466045775	0.161386582837266	0.480805292979384
GO:0019107	myristoyltransferase activity	3/2411	11/18639	0.272727272727273	2.10840466045775	0.161386582837266	0.480805292979384
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	3/2411	11/18639	0.272727272727273	2.10840466045775	0.161386582837266	0.480805292979384
GO:0045294	alpha-catenin binding	3/2411	11/18639	0.272727272727273	2.10840466045775	0.161386582837266	0.480805292979384
GO:0003785	actin monomer binding	6/2411	29/18639	0.206896551724138	1.59947939758864	0.163951112385117	0.48619985052138
GO:0004629	phospholipase C activity	6/2411	29/18639	0.206896551724138	1.59947939758864	0.163951112385117	0.48619985052138
GO:0003725	double-stranded RNA binding	13/2411	75/18639	0.173333333333333	1.34000829531315	0.166020684853676	0.487972697851116
GO:0140313	molecular sequestering activity	10/2411	55/18639	0.181818181818182	1.40560310697183	0.166826561579338	0.487972697851116
GO:0004022	alcohol dehydrogenase (NAD+) activity	5/2411	23/18639	0.217391304347826	1.6806124105098	0.167950988511935	0.487972697851116
GO:0043274	phospholipase binding	5/2411	23/18639	0.217391304347826	1.6806124105098	0.167950988511935	0.487972697851116
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	14/2411	82/18639	0.170731707317073	1.31989560044916	0.168610033123949	0.487972697851116
GO:0033549	MAP kinase phosphatase activity	14/2411	82/18639	0.170731707317073	1.31989560044916	0.168610033123949	0.487972697851116
GO:0004550	nucleoside diphosphate kinase activity	4/2411	17/18639	0.235294117647059	1.81901578549296	0.168709940497363	0.487972697851116
GO:0008569	minus-end-directed microtubule motor activity	4/2411	17/18639	0.235294117647059	1.81901578549296	0.168709940497363	0.487972697851116
GO:0015278	intracellularly gated calcium channel activity	4/2411	17/18639	0.235294117647059	1.81901578549296	0.168709940497363	0.487972697851116
GO:0038191	neuropilin binding	4/2411	17/18639	0.235294117647059	1.81901578549296	0.168709940497363	0.487972697851116
GO:0046965	nuclear retinoid X receptor binding	4/2411	17/18639	0.235294117647059	1.81901578549296	0.168709940497363	0.487972697851116
GO:0015291	secondary active transmembrane transporter activity	43/2411	287/18639	0.149825783972125	1.15827573100641	0.169681319977526	0.489684346243868
GO:0008194	UDP-glycosyltransferase activity	23/2411	145/18639	0.158620689655172	1.22626753815129	0.174861620734456	0.503507791846983
GO:0005484	SNAP receptor activity	7/2411	36/18639	0.194444444444444	1.50321443384488	0.176241245913	0.506350127456057
GO:0140034	methylation-dependent protein binding	13/2411	76/18639	0.171052631578947	1.32237660721692	0.17805069470698	0.510411991493341
GO:0015079	potassium ion transmembrane transporter activity	25/2411	160/18639	0.15625	1.20794017005392	0.18244148210214	0.521839272531619
GO:0032452	histone demethylase activity	6/2411	30/18639	0.2	1.54616341766902	0.183975718088807	0.523904362769451
GO:0033612	receptor serine/threonine kinase binding	6/2411	30/18639	0.2	1.54616341766902	0.183975718088807	0.523904362769451
GO:0008200	ion channel inhibitor activity	8/2411	43/18639	0.186046511627907	1.43829155132002	0.184961772265231	0.52555217229548
GO:0001091	RNA polymerase II general transcription initiation factor binding	5/2411	24/18639	0.208333333333333	1.61058689340523	0.191024841067283	0.54050711804453
GO:0017018	myosin phosphatase activity	14/2411	84/18639	0.166666666666667	1.28846951472418	0.192136830051114	0.54050711804453
GO:0005078	MAP-kinase scaffold activity	3/2411	12/18639	0.25	1.93270427208627	0.195608313480791	0.54050711804453
GO:0015368	calcium:monoatomic cation antiporter activity	3/2411	12/18639	0.25	1.93270427208627	0.195608313480791	0.54050711804453
GO:0016208	AMP binding	3/2411	12/18639	0.25	1.93270427208627	0.195608313480791	0.54050711804453
GO:0016840	carbon-nitrogen lyase activity	3/2411	12/18639	0.25	1.93270427208627	0.195608313480791	0.54050711804453
GO:0035014	phosphatidylinositol 3-kinase regulator activity	3/2411	12/18639	0.25	1.93270427208627	0.195608313480791	0.54050711804453
GO:0045295	gamma-catenin binding	3/2411	12/18639	0.25	1.93270427208627	0.195608313480791	0.54050711804453
GO:0070679	inositol 1,4,5 trisphosphate binding	3/2411	12/18639	0.25	1.93270427208627	0.195608313480791	0.54050711804453
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	3/2411	12/18639	0.25	1.93270427208627	0.195608313480791	0.54050711804453
GO:1990459	transferrin receptor binding	3/2411	12/18639	0.25	1.93270427208627	0.195608313480791	0.54050711804453
GO:0008525	phosphatidylcholine transporter activity	4/2411	18/18639	0.222222222222222	1.71795935296557	0.196090954453365	0.54050711804453
GO:0017075	syntaxin-1 binding	4/2411	18/18639	0.222222222222222	1.71795935296557	0.196090954453365	0.54050711804453
GO:0017128	phospholipid scramblase activity	4/2411	18/18639	0.222222222222222	1.71795935296557	0.196090954453365	0.54050711804453
GO:0016887	ATP hydrolysis activity	60/2411	417/18639	0.143884892086331	1.1123477824957	0.204289607019983	0.56109135700961
GO:0061135	endopeptidase regulator activity	28/2411	184/18639	0.152173913043478	1.17642868735686	0.204428633949238	0.56109135700961
GO:0140457	protein demethylase activity	6/2411	31/18639	0.193548387096774	1.49628717838937	0.204899703955169	0.561190271979124
GO:0005272	sodium channel activity	9/2411	51/18639	0.176470588235294	1.36426183911972	0.207464499130677	0.567011025166468
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	20/2411	128/18639	0.15625	1.20794017005392	0.214510544781157	0.58426053431713
GO:0008483	transaminase activity	5/2411	25/18639	0.2	1.54616341766902	0.215134692868711	0.58426053431713
GO:0015271	outward rectifier potassium channel activity	5/2411	25/18639	0.2	1.54616341766902	0.215134692868711	0.58426053431713
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	14/2411	86/18639	0.162790697674419	1.25850510740501	0.217108989213455	0.588383605221337
GO:0051539	4 iron, 4 sulfur cluster binding	8/2411	45/18639	0.177777777777778	1.37436748237246	0.220078623955971	0.595181184283444
GO:0019842	vitamin binding	23/2411	150/18639	0.153333333333333	1.18539195354625	0.220790931415415	0.595858371393066
GO:0005229	intracellularly calcium-gated chloride channel activity	4/2411	19/18639	0.210526315789474	1.6275404396516	0.224700959949264	0.600132998622258
GO:0022821	solute:potassium antiporter activity	4/2411	19/18639	0.210526315789474	1.6275404396516	0.224700959949264	0.600132998622258
GO:0050145	nucleoside monophosphate kinase activity	4/2411	19/18639	0.210526315789474	1.6275404396516	0.224700959949264	0.600132998622258
GO:0097001	ceramide binding	4/2411	19/18639	0.210526315789474	1.6275404396516	0.224700959949264	0.600132998622258
GO:0141147	intracellularly calcium-gated channel activity	4/2411	19/18639	0.210526315789474	1.6275404396516	0.224700959949264	0.600132998622258
GO:0071813	lipoprotein particle binding	6/2411	32/18639	0.1875	1.4495282040647	0.226623138939237	0.601530553974519
GO:0071814	protein-lipid complex binding	6/2411	32/18639	0.1875	1.4495282040647	0.226623138939237	0.601530553974519
GO:0120015	sterol transfer activity	6/2411	32/18639	0.1875	1.4495282040647	0.226623138939237	0.601530553974519
GO:0043539	protein serine/threonine kinase activator activity	12/2411	73/18639	0.164383561643836	1.27081924739919	0.229654802570271	0.604173289126944
GO:0008081	phosphoric diester hydrolase activity	14/2411	87/18639	0.160919540229885	1.24403953145783	0.230095266717986	0.604173289126944
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	3/2411	13/18639	0.230769230769231	1.78403471269502	0.231365585138535	0.604173289126944
GO:0008035	high-density lipoprotein particle binding	3/2411	13/18639	0.230769230769231	1.78403471269502	0.231365585138535	0.604173289126944
GO:0008253	5'-nucleotidase activity	3/2411	13/18639	0.230769230769231	1.78403471269502	0.231365585138535	0.604173289126944
GO:0061459	L-arginine transmembrane transporter activity	3/2411	13/18639	0.230769230769231	1.78403471269502	0.231365585138535	0.604173289126944
GO:0140333	glycerophospholipid flippase activity	3/2411	13/18639	0.230769230769231	1.78403471269502	0.231365585138535	0.604173289126944
GO:0140410	monoatomic cation:bicarbonate symporter activity	3/2411	13/18639	0.230769230769231	1.78403471269502	0.231365585138535	0.604173289126944
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	7/2411	39/18639	0.179487179487179	1.38758255431835	0.233870656962944	0.609481106024642
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	8/2411	46/18639	0.173913043478261	1.34448992840784	0.238500203643761	0.615832460931184
GO:0046943	carboxylic acid transmembrane transporter activity	28/2411	188/18639	0.148936170212766	1.15139828975352	0.239252153258723	0.615832460931184
GO:0005112	Notch binding	5/2411	26/18639	0.192307692307692	1.48669559391252	0.240126920812702	0.615832460931184
GO:0008066	glutamate receptor activity	5/2411	26/18639	0.192307692307692	1.48669559391252	0.240126920812702	0.615832460931184
GO:0008157	protein phosphatase 1 binding	5/2411	26/18639	0.192307692307692	1.48669559391252	0.240126920812702	0.615832460931184
GO:0030247	polysaccharide binding	5/2411	26/18639	0.192307692307692	1.48669559391252	0.240126920812702	0.615832460931184
GO:0070412	R-SMAD binding	5/2411	26/18639	0.192307692307692	1.48669559391252	0.240126920812702	0.615832460931184
GO:0097602	cullin family protein binding	5/2411	26/18639	0.192307692307692	1.48669559391252	0.240126920812702	0.615832460931184
GO:0015101	organic cation transmembrane transporter activity	13/2411	81/18639	0.160493827160494	1.24074842158625	0.243983043545832	0.623243814206184
GO:0030971	receptor tyrosine kinase binding	13/2411	81/18639	0.160493827160494	1.24074842158625	0.243983043545832	0.623243814206184
GO:0005342	organic acid transmembrane transporter activity	28/2411	189/18639	0.148148148148148	1.14530623531038	0.248349029832923	0.63240894288946
GO:0005267	potassium channel activity	19/2411	124/18639	0.153225806451613	1.18456068289159	0.24855660240914	0.63240894288946
GO:0019956	chemokine binding	6/2411	33/18639	0.181818181818182	1.40560310697183	0.249041661230888	0.63240894288946
GO:0010851	cyclase regulator activity	4/2411	20/18639	0.2	1.54616341766902	0.254283486677901	0.637078196201859
GO:0030742	GTP-dependent protein binding	4/2411	20/18639	0.2	1.54616341766902	0.254283486677901	0.637078196201859
GO:0052745	inositol phosphate phosphatase activity	4/2411	20/18639	0.2	1.54616341766902	0.254283486677901	0.637078196201859
GO:0004177	aminopeptidase activity	7/2411	40/18639	0.175	1.35289299046039	0.254337419413921	0.637078196201859
GO:0015144	carbohydrate transmembrane transporter activity	7/2411	40/18639	0.175	1.35289299046039	0.254337419413921	0.637078196201859
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	7/2411	40/18639	0.175	1.35289299046039	0.254337419413921	0.637078196201859
GO:0140662	ATP-dependent protein folding chaperone	7/2411	40/18639	0.175	1.35289299046039	0.254337419413921	0.637078196201859
GO:0016758	hexosyltransferase activity	29/2411	197/18639	0.147208121827411	1.13803906376654	0.254907683975255	0.637269209938138
GO:0001784	phosphotyrosine residue binding	8/2411	47/18639	0.170212765957447	1.31588375971831	0.25742004424642	0.641065361154212
GO:0140938	histone H3 methyltransferase activity	8/2411	47/18639	0.170212765957447	1.31588375971831	0.25742004424642	0.641065361154212
GO:0032934	sterol binding	11/2411	68/18639	0.161764705882353	1.25057335252641	0.259664380433255	0.64540857564335
GO:0004364	glutathione transferase activity	5/2411	27/18639	0.185185185185185	1.43163279413798	0.265845199326484	0.651464377584275
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	5/2411	27/18639	0.185185185185185	1.43163279413798	0.265845199326484	0.651464377584275
GO:0004705	JUN kinase activity	3/2411	14/18639	0.214285714285714	1.65660366178823	0.268160918214923	0.651464377584275
GO:0008331	high voltage-gated calcium channel activity	3/2411	14/18639	0.214285714285714	1.65660366178823	0.268160918214923	0.651464377584275
GO:0015386	potassium:proton antiporter activity	3/2411	14/18639	0.214285714285714	1.65660366178823	0.268160918214923	0.651464377584275
GO:0032036	myosin heavy chain binding	3/2411	14/18639	0.214285714285714	1.65660366178823	0.268160918214923	0.651464377584275
GO:0032454	histone H3K9 demethylase activity	3/2411	14/18639	0.214285714285714	1.65660366178823	0.268160918214923	0.651464377584275
GO:0034236	protein kinase A catalytic subunit binding	3/2411	14/18639	0.214285714285714	1.65660366178823	0.268160918214923	0.651464377584275
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	3/2411	14/18639	0.214285714285714	1.65660366178823	0.268160918214923	0.651464377584275
GO:0046030	inositol trisphosphate phosphatase activity	3/2411	14/18639	0.214285714285714	1.65660366178823	0.268160918214923	0.651464377584275
GO:0071933	Arp2/3 complex binding	3/2411	14/18639	0.214285714285714	1.65660366178823	0.268160918214923	0.651464377584275
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	3/2411	14/18639	0.214285714285714	1.65660366178823	0.268160918214923	0.651464377584275
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	6/2411	34/18639	0.176470588235294	1.36426183911972	0.272048221765033	0.658428153990417
GO:0090482	vitamin transmembrane transporter activity	6/2411	34/18639	0.176470588235294	1.36426183911972	0.272048221765033	0.658428153990417
GO:0098631	cell adhesion mediator activity	12/2411	76/18639	0.157894736842105	1.2206553297387	0.274310518495392	0.662660241309094
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	7/2411	41/18639	0.170731707317073	1.31989560044916	0.275303709055904	0.663816419966572
GO:0015179	L-amino acid transmembrane transporter activity	10/2411	62/18639	0.161290322580645	1.24690598199114	0.276658291562657	0.665593936771064
GO:0005200	structural constituent of cytoskeleton	17/2411	112/18639	0.151785714285714	1.17342759376666	0.277072824841908	0.665593936771064
GO:0042826	histone deacetylase binding	19/2411	127/18639	0.149606299212598	1.15657893447682	0.283591489049167	0.676091259821939
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	4/2411	21/18639	0.19047619047619	1.47253658825621	0.284587251227374	0.676091259821939
GO:0009975	cyclase activity	4/2411	21/18639	0.19047619047619	1.47253658825621	0.284587251227374	0.676091259821939
GO:0015174	basic amino acid transmembrane transporter activity	4/2411	21/18639	0.19047619047619	1.47253658825621	0.284587251227374	0.676091259821939
GO:0035613	RNA stem-loop binding	4/2411	21/18639	0.19047619047619	1.47253658825621	0.284587251227374	0.676091259821939
GO:0061891	calcium ion sensor activity	4/2411	21/18639	0.19047619047619	1.47253658825621	0.284587251227374	0.676091259821939
GO:0097110	scaffold protein binding	11/2411	70/18639	0.157142857142857	1.21484268531137	0.291980270769809	0.687686253080633
GO:0005242	inward rectifier potassium channel activity	5/2411	28/18639	0.178571428571429	1.38050305149019	0.292133385029602	0.687686253080633
GO:0016866	intramolecular transferase activity	5/2411	28/18639	0.178571428571429	1.38050305149019	0.292133385029602	0.687686253080633
GO:0046875	ephrin receptor binding	5/2411	28/18639	0.178571428571429	1.38050305149019	0.292133385029602	0.687686253080633
GO:0051119	sugar transmembrane transporter activity	5/2411	28/18639	0.178571428571429	1.38050305149019	0.292133385029602	0.687686253080633
GO:0043015	gamma-tubulin binding	6/2411	35/18639	0.171428571428571	1.32528292943059	0.295534703045013	0.693163212596486
GO:0140566	histone reader activity	6/2411	35/18639	0.171428571428571	1.32528292943059	0.295534703045013	0.693163212596486
GO:0003697	single-stranded DNA binding	18/2411	121/18639	0.148760330578512	1.15003890570423	0.299129401195356	0.700321102617076
GO:0099094	ligand-gated monoatomic cation channel activity	20/2411	136/18639	0.147058823529412	1.1368848659331	0.304020051776494	0.706352956204417
GO:0004089	carbonate dehydratase activity	3/2411	15/18639	0.2	1.54616341766902	0.305538720590748	0.706352956204417
GO:0004467	long-chain fatty acid-CoA ligase activity	3/2411	15/18639	0.2	1.54616341766902	0.305538720590748	0.706352956204417
GO:0008242	omega peptidase activity	3/2411	15/18639	0.2	1.54616341766902	0.305538720590748	0.706352956204417
GO:0008252	nucleotidase activity	3/2411	15/18639	0.2	1.54616341766902	0.305538720590748	0.706352956204417
GO:0015556	C4-dicarboxylate transmembrane transporter activity	3/2411	15/18639	0.2	1.54616341766902	0.305538720590748	0.706352956204417
GO:0016846	carbon-sulfur lyase activity	3/2411	15/18639	0.2	1.54616341766902	0.305538720590748	0.706352956204417
GO:0008093	cytoskeletal anchor activity	4/2411	22/18639	0.181818181818182	1.40560310697183	0.315370904052424	0.725184431778301
GO:0050321	tau-protein kinase activity	4/2411	22/18639	0.181818181818182	1.40560310697183	0.315370904052424	0.725184431778301
GO:0140784	metal ion sensor activity	4/2411	22/18639	0.181818181818182	1.40560310697183	0.315370904052424	0.725184431778301
GO:0015605	organophosphate ester transmembrane transporter activity	8/2411	50/18639	0.16	1.23693073413521	0.316556867486062	0.725325682161671
GO:0048020	CCR chemokine receptor binding	8/2411	50/18639	0.16	1.23693073413521	0.316556867486062	0.725325682161671
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	5/2411	29/18639	0.172413793103448	1.33289949799053	0.31883802516387	0.727971561934204
GO:0061134	peptidase regulator activity	32/2411	226/18639	0.141592920353982	1.09462896826125	0.318840257746376	0.727971561934204
GO:0005496	steroid binding	16/2411	108/18639	0.148148148148148	1.14530623531038	0.319882039268602	0.72905977147791
GO:0061980	regulatory RNA binding	9/2411	58/18639	0.155172413793103	1.19960954819148	0.333091240389677	0.757826631574397
GO:0048306	calcium-dependent protein binding	12/2411	80/18639	0.15	1.15962256325176	0.337561336231163	0.761268503767043
GO:0070851	growth factor receptor binding	20/2411	139/18639	0.143884892086331	1.1123477824957	0.340284980757635	0.761268503767043
GO:0019205	nucleobase-containing compound kinase activity	7/2411	44/18639	0.159090909090909	1.22990271860035	0.340398206163041	0.761268503767043
GO:1990782	protein tyrosine kinase binding	17/2411	117/18639	0.145299145299145	1.12328111540057	0.3423301109461	0.761268503767043
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	3/2411	16/18639	0.1875	1.4495282040647	0.343090666177483	0.761268503767043
GO:0004707	MAP kinase activity	3/2411	16/18639	0.1875	1.4495282040647	0.343090666177483	0.761268503767043
GO:0005159	insulin-like growth factor receptor binding	3/2411	16/18639	0.1875	1.4495282040647	0.343090666177483	0.761268503767043
GO:0005324	long-chain fatty acid transmembrane transporter activity	3/2411	16/18639	0.1875	1.4495282040647	0.343090666177483	0.761268503767043
GO:0031435	mitogen-activated protein kinase kinase kinase binding	3/2411	16/18639	0.1875	1.4495282040647	0.343090666177483	0.761268503767043
GO:0034450	ubiquitin-ubiquitin ligase activity	3/2411	16/18639	0.1875	1.4495282040647	0.343090666177483	0.761268503767043
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	3/2411	16/18639	0.1875	1.4495282040647	0.343090666177483	0.761268503767043
GO:0055102	lipase inhibitor activity	3/2411	16/18639	0.1875	1.4495282040647	0.343090666177483	0.761268503767043
GO:0140328	floppase activity	3/2411	16/18639	0.1875	1.4495282040647	0.343090666177483	0.761268503767043
GO:0019213	deacetylase activity	6/2411	37/18639	0.162162162162162	1.25364601432623	0.343518311912924	0.761268503767043
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	5/2411	30/18639	0.166666666666667	1.28846951472418	0.345810486578883	0.761268503767043
GO:0016769	transferase activity, transferring nitrogenous groups	5/2411	30/18639	0.166666666666667	1.28846951472418	0.345810486578883	0.761268503767043
GO:0031210	phosphatidylcholine binding	5/2411	30/18639	0.166666666666667	1.28846951472418	0.345810486578883	0.761268503767043
GO:0098918	structural constituent of synapse	5/2411	30/18639	0.166666666666667	1.28846951472418	0.345810486578883	0.761268503767043
GO:0016849	phosphorus-oxygen lyase activity	4/2411	23/18639	0.173913043478261	1.34448992840784	0.346406675745158	0.761268503767043
GO:0099186	structural constituent of postsynapse	4/2411	23/18639	0.173913043478261	1.34448992840784	0.346406675745158	0.761268503767043
GO:0016757	glycosyltransferase activity	37/2411	267/18639	0.138576779026217	1.0713117313437	0.352123887278182	0.764471610986583
GO:0045309	protein phosphorylated amino acid binding	9/2411	59/18639	0.152542372881356	1.17927718296789	0.352201497478175	0.764471610986583
GO:0004722	protein serine/threonine phosphatase activity	15/2411	103/18639	0.145631067961165	1.12584714878812	0.352761248679879	0.764471610986583
GO:0005126	cytokine receptor binding	38/2411	275/18639	0.138181818181818	1.06825836129859	0.356446769317428	0.764471610986583
GO:0016829	lyase activity	28/2411	200/18639	0.14	1.08231439236831	0.356584823898631	0.764471610986583
GO:0005085	guanyl-nucleotide exchange factor activity	32/2411	230/18639	0.139130434782609	1.07559194272627	0.356956244697379	0.764471610986583
GO:0004715	non-membrane spanning protein tyrosine kinase activity	7/2411	45/18639	0.155555555555556	1.2025715470759	0.362562339727501	0.764471610986583
GO:0008009	chemokine activity	7/2411	45/18639	0.155555555555556	1.2025715470759	0.362562339727501	0.764471610986583
GO:0000146	microfilament motor activity	6/2411	38/18639	0.157894736842105	1.2206553297387	0.367806354946944	0.764471610986583
GO:0004175	endopeptidase activity	55/2411	405/18639	0.135802469135802	1.04986404903452	0.369926989260817	0.764471610986583
GO:0001098	basal transcription machinery binding	9/2411	60/18639	0.15	1.15962256325176	0.371451353544667	0.764471610986583
GO:0001099	basal RNA polymerase II transcription machinery binding	9/2411	60/18639	0.15	1.15962256325176	0.371451353544667	0.764471610986583
GO:0008327	methyl-CpG binding	5/2411	31/18639	0.161290322580645	1.24690598199114	0.37290871400652	0.764471610986583
GO:0072349	modified amino acid transmembrane transporter activity	5/2411	31/18639	0.161290322580645	1.24690598199114	0.37290871400652	0.764471610986583
GO:0043022	ribosome binding	16/2411	112/18639	0.142857142857143	1.10440244119216	0.375455537921163	0.764471610986583
GO:0019003	GDP binding	11/2411	75/18639	0.146666666666667	1.13385317295728	0.376675241634596	0.764471610986583
GO:0004622	lysophospholipase activity	4/2411	24/18639	0.166666666666667	1.28846951472418	0.377483042680733	0.764471610986583
GO:0005315	phosphate transmembrane transporter activity	4/2411	24/18639	0.166666666666667	1.28846951472418	0.377483042680733	0.764471610986583
GO:0015149	hexose transmembrane transporter activity	4/2411	24/18639	0.166666666666667	1.28846951472418	0.377483042680733	0.764471610986583
GO:0015295	solute:proton symporter activity	4/2411	24/18639	0.166666666666667	1.28846951472418	0.377483042680733	0.764471610986583
GO:0030215	semaphorin receptor binding	4/2411	24/18639	0.166666666666667	1.28846951472418	0.377483042680733	0.764471610986583
GO:0030552	cAMP binding	4/2411	24/18639	0.166666666666667	1.28846951472418	0.377483042680733	0.764471610986583
GO:0035035	histone acetyltransferase binding	4/2411	24/18639	0.166666666666667	1.28846951472418	0.377483042680733	0.764471610986583
GO:0055056	D-glucose transmembrane transporter activity	4/2411	24/18639	0.166666666666667	1.28846951472418	0.377483042680733	0.764471610986583
GO:0031406	carboxylic acid binding	26/2411	187/18639	0.13903743315508	1.07487296415493	0.377774986495102	0.764471610986583
GO:0000182	rDNA binding	2/2411	10/18639	0.2	1.54616341766902	0.377898209157061	0.764471610986583
GO:0001094	TFIID-class transcription factor complex binding	2/2411	10/18639	0.2	1.54616341766902	0.377898209157061	0.764471610986583
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	2/2411	10/18639	0.2	1.54616341766902	0.377898209157061	0.764471610986583
GO:0004445	inositol-polyphosphate 5-phosphatase activity	2/2411	10/18639	0.2	1.54616341766902	0.377898209157061	0.764471610986583
GO:0004955	prostaglandin receptor activity	2/2411	10/18639	0.2	1.54616341766902	0.377898209157061	0.764471610986583
GO:0005381	iron ion transmembrane transporter activity	2/2411	10/18639	0.2	1.54616341766902	0.377898209157061	0.764471610986583
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	2/2411	10/18639	0.2	1.54616341766902	0.377898209157061	0.764471610986583
GO:0008519	ammonium channel activity	2/2411	10/18639	0.2	1.54616341766902	0.377898209157061	0.764471610986583
GO:0015279	store-operated calcium channel activity	2/2411	10/18639	0.2	1.54616341766902	0.377898209157061	0.764471610986583
GO:0031434	mitogen-activated protein kinase kinase binding	2/2411	10/18639	0.2	1.54616341766902	0.377898209157061	0.764471610986583
GO:0035256	G protein-coupled glutamate receptor binding	2/2411	10/18639	0.2	1.54616341766902	0.377898209157061	0.764471610986583
GO:0043208	glycosphingolipid binding	2/2411	10/18639	0.2	1.54616341766902	0.377898209157061	0.764471610986583
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	2/2411	10/18639	0.2	1.54616341766902	0.377898209157061	0.764471610986583
GO:0043295	glutathione binding	2/2411	10/18639	0.2	1.54616341766902	0.377898209157061	0.764471610986583
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	2/2411	10/18639	0.2	1.54616341766902	0.377898209157061	0.764471610986583
GO:0051864	histone H3K36 demethylase activity	2/2411	10/18639	0.2	1.54616341766902	0.377898209157061	0.764471610986583
GO:0099122	RNA polymerase II C-terminal domain binding	2/2411	10/18639	0.2	1.54616341766902	0.377898209157061	0.764471610986583
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/2411	17/18639	0.176470588235294	1.36426183911972	0.380457964537509	0.764471610986583
GO:0005092	GDP-dissociation inhibitor activity	3/2411	17/18639	0.176470588235294	1.36426183911972	0.380457964537509	0.764471610986583
GO:0008429	phosphatidylethanolamine binding	3/2411	17/18639	0.176470588235294	1.36426183911972	0.380457964537509	0.764471610986583
GO:0008484	sulfuric ester hydrolase activity	3/2411	17/18639	0.176470588235294	1.36426183911972	0.380457964537509	0.764471610986583
GO:0009881	photoreceptor activity	3/2411	17/18639	0.176470588235294	1.36426183911972	0.380457964537509	0.764471610986583
GO:0015347	sodium-independent organic anion transmembrane transporter activity	3/2411	17/18639	0.176470588235294	1.36426183911972	0.380457964537509	0.764471610986583
GO:0019198	transmembrane receptor protein phosphatase activity	3/2411	17/18639	0.176470588235294	1.36426183911972	0.380457964537509	0.764471610986583
GO:0030169	low-density lipoprotein particle binding	3/2411	17/18639	0.176470588235294	1.36426183911972	0.380457964537509	0.764471610986583
GO:0031489	myosin V binding	3/2411	17/18639	0.176470588235294	1.36426183911972	0.380457964537509	0.764471610986583
GO:0045236	CXCR chemokine receptor binding	3/2411	17/18639	0.176470588235294	1.36426183911972	0.380457964537509	0.764471610986583
GO:0070403	NAD+ binding	3/2411	17/18639	0.176470588235294	1.36426183911972	0.380457964537509	0.764471610986583
GO:0070492	oligosaccharide binding	3/2411	17/18639	0.176470588235294	1.36426183911972	0.380457964537509	0.764471610986583
GO:1990226	histone methyltransferase binding	3/2411	17/18639	0.176470588235294	1.36426183911972	0.380457964537509	0.764471610986583
GO:0004180	carboxypeptidase activity	7/2411	46/18639	0.152173913043478	1.17642868735686	0.384829902614326	0.772053770408213
GO:0005249	voltage-gated potassium channel activity	14/2411	98/18639	0.142857142857143	1.10440244119216	0.388582595085437	0.778371968416481
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	25/2411	181/18639	0.138121546961326	1.06779241551728	0.394634972961092	0.789269945922185
GO:0043177	organic acid binding	26/2411	189/18639	0.137566137566138	1.06349864707393	0.399686715968302	0.798136011763328
GO:0005216	monoatomic ion channel activity	60/2411	448/18639	0.133928571428571	1.03537728861765	0.406411447931238	0.808043610228681
GO:0003707	nuclear steroid receptor activity	4/2411	25/18639	0.16	1.23693073413521	0.408406537883023	0.808043610228681
GO:0017025	TBP-class protein binding	4/2411	25/18639	0.16	1.23693073413521	0.408406537883023	0.808043610228681
GO:0019211	phosphatase activator activity	4/2411	25/18639	0.16	1.23693073413521	0.408406537883023	0.808043610228681
GO:0019706	protein-cysteine S-palmitoyltransferase activity	4/2411	25/18639	0.16	1.23693073413521	0.408406537883023	0.808043610228681
GO:0019707	protein-cysteine S-acyltransferase activity	4/2411	25/18639	0.16	1.23693073413521	0.408406537883023	0.808043610228681
GO:0030331	nuclear estrogen receptor binding	6/2411	40/18639	0.15	1.15962256325176	0.416479631909243	0.810553622454695
GO:0032451	demethylase activity	6/2411	40/18639	0.15	1.15962256325176	0.416479631909243	0.810553622454695
GO:0050997	quaternary ammonium group binding	6/2411	40/18639	0.15	1.15962256325176	0.416479631909243	0.810553622454695
GO:0008308	voltage-gated monoatomic anion channel activity	3/2411	18/18639	0.166666666666667	1.28846951472418	0.417331366554338	0.810553622454695
GO:0015280	ligand-gated sodium channel activity	3/2411	18/18639	0.166666666666667	1.28846951472418	0.417331366554338	0.810553622454695
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	3/2411	18/18639	0.166666666666667	1.28846951472418	0.417331366554338	0.810553622454695
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	3/2411	18/18639	0.166666666666667	1.28846951472418	0.417331366554338	0.810553622454695
GO:0050811	GABA receptor binding	3/2411	18/18639	0.166666666666667	1.28846951472418	0.417331366554338	0.810553622454695
GO:1901611	phosphatidylglycerol binding	3/2411	18/18639	0.166666666666667	1.28846951472418	0.417331366554338	0.810553622454695
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	2/2411	11/18639	0.181818181818182	1.40560310697183	0.426011903894793	0.810553622454695
GO:0004954	prostanoid receptor activity	2/2411	11/18639	0.181818181818182	1.40560310697183	0.426011903894793	0.810553622454695
GO:0008046	axon guidance receptor activity	2/2411	11/18639	0.181818181818182	1.40560310697183	0.426011903894793	0.810553622454695
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	2/2411	11/18639	0.181818181818182	1.40560310697183	0.426011903894793	0.810553622454695
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	2/2411	11/18639	0.181818181818182	1.40560310697183	0.426011903894793	0.810553622454695
GO:0019203	carbohydrate phosphatase activity	2/2411	11/18639	0.181818181818182	1.40560310697183	0.426011903894793	0.810553622454695
GO:0019206	nucleoside kinase activity	2/2411	11/18639	0.181818181818182	1.40560310697183	0.426011903894793	0.810553622454695
GO:0019215	intermediate filament binding	2/2411	11/18639	0.181818181818182	1.40560310697183	0.426011903894793	0.810553622454695
GO:0032794	GTPase activating protein binding	2/2411	11/18639	0.181818181818182	1.40560310697183	0.426011903894793	0.810553622454695
GO:0034713	type I transforming growth factor beta receptor binding	2/2411	11/18639	0.181818181818182	1.40560310697183	0.426011903894793	0.810553622454695
GO:0035252	UDP-xylosyltransferase activity	2/2411	11/18639	0.181818181818182	1.40560310697183	0.426011903894793	0.810553622454695
GO:0042285	xylosyltransferase activity	2/2411	11/18639	0.181818181818182	1.40560310697183	0.426011903894793	0.810553622454695
GO:0042608	T cell receptor binding	2/2411	11/18639	0.181818181818182	1.40560310697183	0.426011903894793	0.810553622454695
GO:0047676	arachidonate-CoA ligase activity	2/2411	11/18639	0.181818181818182	1.40560310697183	0.426011903894793	0.810553622454695
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	2/2411	11/18639	0.181818181818182	1.40560310697183	0.426011903894793	0.810553622454695
GO:0097493	structural molecule activity conferring elasticity	2/2411	11/18639	0.181818181818182	1.40560310697183	0.426011903894793	0.810553622454695
GO:1900750	oligopeptide binding	2/2411	11/18639	0.181818181818182	1.40560310697183	0.426011903894793	0.810553622454695
GO:0005507	copper ion binding	9/2411	63/18639	0.142857142857143	1.10440244119216	0.429547251297682	0.816076515720192
GO:0043021	ribonucleoprotein complex binding	24/2411	177/18639	0.135593220338983	1.04824638486035	0.435324698740833	0.82583656084658
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	4/2411	26/18639	0.153846153846154	1.18935647513001	0.439002831895809	0.82673526006656
GO:0015145	monosaccharide transmembrane transporter activity	4/2411	26/18639	0.153846153846154	1.18935647513001	0.439002831895809	0.82673526006656
GO:0034237	protein kinase A regulatory subunit binding	4/2411	26/18639	0.153846153846154	1.18935647513001	0.439002831895809	0.82673526006656
GO:0050681	nuclear androgen receptor binding	4/2411	26/18639	0.153846153846154	1.18935647513001	0.439002831895809	0.82673526006656
GO:0052742	phosphatidylinositol kinase activity	4/2411	26/18639	0.153846153846154	1.18935647513001	0.439002831895809	0.82673526006656
GO:0001727	lipid kinase activity	6/2411	41/18639	0.146341463414634	1.13133908609928	0.440681218684101	0.827480017616435
GO:0008227	G protein-coupled amine receptor activity	6/2411	41/18639	0.146341463414634	1.13133908609928	0.440681218684101	0.827480017616435
GO:0016835	carbon-oxygen lyase activity	11/2411	79/18639	0.139240506329114	1.07644288571894	0.446106307102854	0.836449325817852
GO:0015245	fatty acid transmembrane transporter activity	3/2411	19/18639	0.157894736842105	1.2206553297387	0.45344956779279	0.844481549527516
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/2411	19/18639	0.157894736842105	1.2206553297387	0.45344956779279	0.844481549527516
GO:0030506	ankyrin binding	3/2411	19/18639	0.157894736842105	1.2206553297387	0.45344956779279	0.844481549527516
GO:0008175	tRNA methyltransferase activity	5/2411	34/18639	0.147058823529412	1.1368848659331	0.453663344048503	0.844481549527516
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	5/2411	34/18639	0.147058823529412	1.1368848659331	0.453663344048503	0.844481549527516
GO:0042379	chemokine receptor binding	10/2411	72/18639	0.138888888888889	1.07372459560348	0.456597941868883	0.848719517306714
GO:0015932	nucleobase-containing compound transmembrane transporter activity	8/2411	57/18639	0.140350877192982	1.08502695976773	0.460477871670042	0.852940451472123
GO:0035198	miRNA binding	6/2411	42/18639	0.142857142857143	1.10440244119216	0.46467983872756	0.852940451472123
GO:0043175	RNA polymerase core enzyme binding	6/2411	42/18639	0.142857142857143	1.10440244119216	0.46467983872756	0.852940451472123
GO:0001671	ATPase activator activity	4/2411	27/18639	0.148148148148148	1.14530623531038	0.469117202777431	0.852940451472123
GO:0005385	zinc ion transmembrane transporter activity	4/2411	27/18639	0.148148148148148	1.14530623531038	0.469117202777431	0.852940451472123
GO:0000340	RNA 7-methylguanosine cap binding	2/2411	12/18639	0.166666666666667	1.28846951472418	0.472092621977594	0.852940451472123
GO:0003995	acyl-CoA dehydrogenase activity	2/2411	12/18639	0.166666666666667	1.28846951472418	0.472092621977594	0.852940451472123
GO:0004000	adenosine deaminase activity	2/2411	12/18639	0.166666666666667	1.28846951472418	0.472092621977594	0.852940451472123
GO:0005095	GTPase inhibitor activity	2/2411	12/18639	0.166666666666667	1.28846951472418	0.472092621977594	0.852940451472123
GO:0005165	neurotrophin receptor binding	2/2411	12/18639	0.166666666666667	1.28846951472418	0.472092621977594	0.852940451472123
GO:0005247	voltage-gated chloride channel activity	2/2411	12/18639	0.166666666666667	1.28846951472418	0.472092621977594	0.852940451472123
GO:0005436	sodium:phosphate symporter activity	2/2411	12/18639	0.166666666666667	1.28846951472418	0.472092621977594	0.852940451472123
GO:0015132	prostaglandin transmembrane transporter activity	2/2411	12/18639	0.166666666666667	1.28846951472418	0.472092621977594	0.852940451472123
GO:0016801	hydrolase activity, acting on ether bonds	2/2411	12/18639	0.166666666666667	1.28846951472418	0.472092621977594	0.852940451472123
GO:0016803	ether hydrolase activity	2/2411	12/18639	0.166666666666667	1.28846951472418	0.472092621977594	0.852940451472123
GO:0034452	dynactin binding	2/2411	12/18639	0.166666666666667	1.28846951472418	0.472092621977594	0.852940451472123
GO:0035497	cAMP response element binding	2/2411	12/18639	0.166666666666667	1.28846951472418	0.472092621977594	0.852940451472123
GO:0042301	phosphate ion binding	2/2411	12/18639	0.166666666666667	1.28846951472418	0.472092621977594	0.852940451472123
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	2/2411	12/18639	0.166666666666667	1.28846951472418	0.472092621977594	0.852940451472123
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	2/2411	12/18639	0.166666666666667	1.28846951472418	0.472092621977594	0.852940451472123
GO:0140597	protein carrier chaperone	25/2411	188/18639	0.132978723404255	1.02803418727993	0.473610639288819	0.85448632822738
GO:0004521	RNA endonuclease activity	10/2411	73/18639	0.136986301369863	1.05901603949933	0.474739529071984	0.855326805171592
GO:0005154	epidermal growth factor receptor binding	5/2411	35/18639	0.142857142857143	1.10440244119216	0.480018117549085	0.863630922787056
GO:0004712	protein serine/threonine/tyrosine kinase activity	6/2411	43/18639	0.13953488372093	1.07871866349001	0.488398569213345	0.871769730340126
GO:0000339	RNA cap binding	3/2411	20/18639	0.15	1.15962256325176	0.488596523283652	0.871769730340126
GO:0001972	retinoic acid binding	3/2411	20/18639	0.15	1.15962256325176	0.488596523283652	0.871769730340126
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	3/2411	20/18639	0.15	1.15962256325176	0.488596523283652	0.871769730340126
GO:0043024	ribosomal small subunit binding	3/2411	20/18639	0.15	1.15962256325176	0.488596523283652	0.871769730340126
GO:0061608	nuclear import signal receptor activity	3/2411	20/18639	0.15	1.15962256325176	0.488596523283652	0.871769730340126
GO:0030544	Hsp70 protein binding	7/2411	51/18639	0.137254901960784	1.06109254153756	0.495237244146153	0.882397852138863
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	22/2411	167/18639	0.131736526946108	1.0184309936742	0.498124664215493	0.883296393266198
GO:0045499	chemorepellent activity	4/2411	28/18639	0.142857142857143	1.10440244119216	0.498614505735402	0.883296393266198
GO:0046625	sphingolipid binding	4/2411	28/18639	0.142857142857143	1.10440244119216	0.498614505735402	0.883296393266198
GO:0046966	nuclear thyroid hormone receptor binding	4/2411	28/18639	0.142857142857143	1.10440244119216	0.498614505735402	0.883296393266198
GO:0017171	serine hydrolase activity	26/2411	198/18639	0.131313131313131	1.01515779947966	0.49916517107834	0.883296393266198
GO:0001786	phosphatidylserine binding	8/2411	59/18639	0.135593220338983	1.04824638486035	0.501041416627327	0.884190735224694
GO:0070888	E-box binding	8/2411	59/18639	0.135593220338983	1.04824638486035	0.501041416627327	0.884190735224694
GO:0004869	cysteine-type endopeptidase inhibitor activity	5/2411	36/18639	0.138888888888889	1.07372459560348	0.505925330948709	0.890690540544419
GO:0042054	histone methyltransferase activity	9/2411	67/18639	0.134328358208955	1.03846796709113	0.506105555208573	0.890690540544419
GO:0030547	signaling receptor inhibitor activity	6/2411	44/18639	0.136363636363636	1.05420233022888	0.51176704758971	0.894436713209533
GO:0016741	transferase activity, transferring one-carbon groups	28/2411	215/18639	0.130232558139535	1.00680408592401	0.515462200546089	0.894436713209533
GO:0015651	quaternary ammonium group transmembrane transporter activity	2/2411	13/18639	0.153846153846154	1.18935647513001	0.515861174130149	0.894436713209533
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	2/2411	13/18639	0.153846153846154	1.18935647513001	0.515861174130149	0.894436713209533
GO:0017154	semaphorin receptor activity	2/2411	13/18639	0.153846153846154	1.18935647513001	0.515861174130149	0.894436713209533
GO:0031432	titin binding	2/2411	13/18639	0.153846153846154	1.18935647513001	0.515861174130149	0.894436713209533
GO:0046974	histone H3K9 methyltransferase activity	2/2411	13/18639	0.153846153846154	1.18935647513001	0.515861174130149	0.894436713209533
GO:0070700	BMP receptor binding	2/2411	13/18639	0.153846153846154	1.18935647513001	0.515861174130149	0.894436713209533
GO:0071714	icosanoid transmembrane transporter activity	2/2411	13/18639	0.153846153846154	1.18935647513001	0.515861174130149	0.894436713209533
GO:0071837	HMG box domain binding	2/2411	13/18639	0.153846153846154	1.18935647513001	0.515861174130149	0.894436713209533
GO:0097157	pre-mRNA intronic binding	2/2411	13/18639	0.153846153846154	1.18935647513001	0.515861174130149	0.894436713209533
GO:0001846	opsonin binding	3/2411	21/18639	0.142857142857143	1.10440244119216	0.522598068626366	0.901272070224614
GO:0008373	sialyltransferase activity	3/2411	21/18639	0.142857142857143	1.10440244119216	0.522598068626366	0.901272070224614
GO:0009931	calcium-dependent protein serine/threonine kinase activity	3/2411	21/18639	0.142857142857143	1.10440244119216	0.522598068626366	0.901272070224614
GO:0072542	protein phosphatase activator activity	3/2411	21/18639	0.142857142857143	1.10440244119216	0.522598068626366	0.901272070224614
GO:0030145	manganese ion binding	9/2411	68/18639	0.132352941176471	1.02319637933979	0.524807308487663	0.902066993091094
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	4/2411	29/18639	0.137931034482759	1.06631959839243	0.527378742626847	0.902066993091094
GO:0016417	S-acyltransferase activity	4/2411	29/18639	0.137931034482759	1.06631959839243	0.527378742626847	0.902066993091094
GO:0051861	glycolipid binding	4/2411	29/18639	0.137931034482759	1.06631959839243	0.527378742626847	0.902066993091094
GO:0097472	cyclin-dependent protein kinase activity	4/2411	29/18639	0.137931034482759	1.06631959839243	0.527378742626847	0.902066993091094
GO:0106222	lncRNA binding	4/2411	29/18639	0.137931034482759	1.06631959839243	0.527378742626847	0.902066993091094
GO:0022804	active transmembrane transporter activity	59/2411	457/18639	0.12910284463895	0.998070477488753	0.527953937816881	0.902066993091094
GO:0030551	cyclic nucleotide binding	5/2411	37/18639	0.135135135135135	1.04470501193853	0.53130142767305	0.90658576944211
GO:0043178	alcohol binding	12/2411	92/18639	0.130434782608696	1.00836744630588	0.534453702574378	0.910014363138211
GO:0046915	transition metal ion transmembrane transporter activity	6/2411	45/18639	0.133333333333333	1.03077561177934	0.53472161803005	0.910014363138211
GO:1901505	carbohydrate derivative transmembrane transporter activity	7/2411	53/18639	0.132075471698113	1.02105131355501	0.53780117363713	0.914049425549273
GO:0002039	p53 binding	9/2411	69/18639	0.130434782608696	1.00836744630588	0.543261195476637	0.920902683528071
GO:0016279	protein-lysine N-methyltransferase activity	9/2411	69/18639	0.130434782608696	1.00836744630588	0.543261195476637	0.920902683528071
GO:0005125	cytokine activity	30/2411	234/18639	0.128205128205128	0.991130395941677	0.55065887704368	0.927376089870538
GO:0048019	receptor antagonist activity	4/2411	30/18639	0.133333333333333	1.03077561177934	0.55531232048038	0.927376089870538
GO:0004407	histone deacetylase activity	3/2411	22/18639	0.136363636363636	1.05420233022888	0.555318147243304	0.927376089870538
GO:0005243	gap junction channel activity	3/2411	22/18639	0.136363636363636	1.05420233022888	0.555318147243304	0.927376089870538
GO:0033558	protein lysine deacetylase activity	3/2411	22/18639	0.136363636363636	1.05420233022888	0.555318147243304	0.927376089870538
GO:0070034	telomerase RNA binding	3/2411	22/18639	0.136363636363636	1.05420233022888	0.555318147243304	0.927376089870538
GO:0001664	G protein-coupled receptor binding	38/2411	297/18639	0.127946127946128	0.989128112313513	0.555452548709115	0.927376089870538
GO:0005501	retinoid binding	5/2411	38/18639	0.131578947368421	1.01721277478225	0.556073408389127	0.927376089870538
GO:0019840	isoprenoid binding	5/2411	38/18639	0.131578947368421	1.01721277478225	0.556073408389127	0.927376089870538
GO:0042887	amide transmembrane transporter activity	5/2411	38/18639	0.131578947368421	1.01721277478225	0.556073408389127	0.927376089870538
GO:0004065	arylsulfatase activity	2/2411	14/18639	0.142857142857143	1.10440244119216	0.557144550116021	0.927376089870538
GO:0005313	L-glutamate transmembrane transporter activity	2/2411	14/18639	0.142857142857143	1.10440244119216	0.557144550116021	0.927376089870538
GO:0019992	diacylglycerol binding	2/2411	14/18639	0.142857142857143	1.10440244119216	0.557144550116021	0.927376089870538
GO:0044548	S100 protein binding	2/2411	14/18639	0.142857142857143	1.10440244119216	0.557144550116021	0.927376089870538
GO:0015485	cholesterol binding	7/2411	54/18639	0.12962962962963	1.00214295589659	0.558529770088485	0.92848376728627
GO:0016278	lysine N-methyltransferase activity	9/2411	70/18639	0.128571428571429	0.993962197072939	0.561435236715196	0.932112555164225
GO:0016209	antioxidant activity	11/2411	86/18639	0.127906976744186	0.988825441532511	0.564447636855847	0.935909320750698
GO:0061630	ubiquitin protein ligase activity	45/2411	353/18639	0.127478753541076	0.985514926276286	0.566483489538368	0.938079206039146
GO:0008238	exopeptidase activity	13/2411	102/18639	0.127450980392157	0.985300217142021	0.567448073719956	0.938471814229158
GO:0140658	ATP-dependent chromatin remodeler activity	20/2411	158/18639	0.126582278481013	0.978584441562669	0.577413399538462	0.953730198981582
GO:0098632	cell-cell adhesion mediator activity	7/2411	55/18639	0.127272727272727	0.983922174880283	0.578833003694984	0.953847960418984
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	29/2411	229/18639	0.126637554585153	0.979011771013133	0.578963529463616	0.953847960418984
GO:0033293	monocarboxylic acid binding	10/2411	79/18639	0.126582278481013	0.978584441562669	0.579870265677872	0.954123268781193
GO:0008276	protein methyltransferase activity	12/2411	95/18639	0.126315789473684	0.976524263790958	0.5813846492419	0.955396429964396
GO:0003887	DNA-directed DNA polymerase activity	3/2411	23/18639	0.130434782608696	1.00836744630588	0.586654867968025	0.957223598584238
GO:0004602	glutathione peroxidase activity	3/2411	23/18639	0.130434782608696	1.00836744630588	0.586654867968025	0.957223598584238
GO:0005212	structural constituent of eye lens	3/2411	23/18639	0.130434782608696	1.00836744630588	0.586654867968025	0.957223598584238
GO:0000510	H3-H4 histone complex chaperone activity	19/2411	151/18639	0.125827814569536	0.972751819063289	0.588256033276319	0.957223598584238
GO:0140584	chromatin extrusion motor activity	19/2411	151/18639	0.125827814569536	0.972751819063289	0.588256033276319	0.957223598584238
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	19/2411	151/18639	0.125827814569536	0.972751819063289	0.588256033276319	0.957223598584238
GO:0140849	ATP-dependent H2AZ histone chaperone activity	19/2411	151/18639	0.125827814569536	0.972751819063289	0.588256033276319	0.957223598584238
GO:0061659	ubiquitin-like protein ligase activity	47/2411	372/18639	0.126344086021505	0.976743019226395	0.592960263645183	0.957223598584238
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	2/2411	15/18639	0.133333333333333	1.03077561177934	0.595853139273755	0.957223598584238
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	2/2411	15/18639	0.133333333333333	1.03077561177934	0.595853139273755	0.957223598584238
GO:0004953	icosanoid receptor activity	2/2411	15/18639	0.133333333333333	1.03077561177934	0.595853139273755	0.957223598584238
GO:0005041	low-density lipoprotein particle receptor activity	2/2411	15/18639	0.133333333333333	1.03077561177934	0.595853139273755	0.957223598584238
GO:0005402	carbohydrate:monoatomic cation symporter activity	2/2411	15/18639	0.133333333333333	1.03077561177934	0.595853139273755	0.957223598584238
GO:0030553	cGMP binding	2/2411	15/18639	0.133333333333333	1.03077561177934	0.595853139273755	0.957223598584238
GO:0034483	heparan sulfate sulfotransferase activity	2/2411	15/18639	0.133333333333333	1.03077561177934	0.595853139273755	0.957223598584238
GO:0061578	K63-linked deubiquitinase activity	2/2411	15/18639	0.133333333333333	1.03077561177934	0.595853139273755	0.957223598584238
GO:0141050	histone H3K deacetylase activity	2/2411	15/18639	0.133333333333333	1.03077561177934	0.595853139273755	0.957223598584238
GO:0141051	histone H4K deacetylase activity	2/2411	15/18639	0.133333333333333	1.03077561177934	0.595853139273755	0.957223598584238
GO:0015616	DNA translocase activity	19/2411	152/18639	0.125	0.966352136043136	0.600322382560746	0.962007296277469
GO:0140674	ATP-dependent histone chaperone activity	19/2411	152/18639	0.125	0.966352136043136	0.600322382560746	0.962007296277469
GO:0022836	gated channel activity	40/2411	318/18639	0.125786163522013	0.972429822433344	0.601254172936904	0.962305065866757
GO:0043425	bHLH transcription factor binding	4/2411	32/18639	0.125	0.966352136043136	0.608383140092133	0.969642786215674
GO:0051059	NF-kappaB binding	4/2411	32/18639	0.125	0.966352136043136	0.608383140092133	0.969642786215674
GO:0003727	single-stranded RNA binding	11/2411	89/18639	0.123595505617978	0.955494246874112	0.612031353909195	0.969642786215674
GO:0061775	cohesin loader activity	19/2411	153/18639	0.124183006535948	0.960036109010174	0.612238622025266	0.969642786215674
GO:0048027	mRNA 5'-UTR binding	3/2411	24/18639	0.125	0.966352136043136	0.616536557294782	0.969642786215674
GO:0050699	WW domain binding	3/2411	24/18639	0.125	0.966352136043136	0.616536557294782	0.969642786215674
GO:0140612	DNA damage sensor activity	3/2411	24/18639	0.125	0.966352136043136	0.616536557294782	0.969642786215674
GO:0004601	peroxidase activity	7/2411	57/18639	0.12280701754386	0.949398589796765	0.618021857190955	0.969642786215674
GO:0070279	vitamin B6 binding	7/2411	57/18639	0.12280701754386	0.949398589796765	0.618021857190955	0.969642786215674
GO:0016763	pentosyltransferase activity	6/2411	49/18639	0.122448979591837	0.94663066387899	0.621362476450894	0.969642786215674
GO:0015293	symporter activity	18/2411	146/18639	0.123287671232877	0.953114435549394	0.623926009436279	0.969642786215674
GO:0008236	serine-type peptidase activity	24/2411	194/18639	0.123711340206186	0.956389742888052	0.62531630324833	0.969642786215674
GO:0015175	neutral L-amino acid transmembrane transporter activity	5/2411	41/18639	0.121951219512195	0.942782571749401	0.62618676131429	0.969642786215674
GO:0046982	protein heterodimerization activity	46/2411	369/18639	0.124661246612466	0.963733295566054	0.630444355665309	0.969642786215674
GO:0031491	nucleosome binding	9/2411	74/18639	0.121621621621622	0.940234510744672	0.630785046881816	0.969642786215674
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	2/2411	16/18639	0.125	0.966352136043136	0.631962064001793	0.969642786215674
GO:0008296	3'-5'-DNA exonuclease activity	2/2411	16/18639	0.125	0.966352136043136	0.631962064001793	0.969642786215674
GO:0015378	sodium:chloride symporter activity	2/2411	16/18639	0.125	0.966352136043136	0.631962064001793	0.969642786215674
GO:0015562	efflux transmembrane transporter activity	2/2411	16/18639	0.125	0.966352136043136	0.631962064001793	0.969642786215674
GO:0022858	alanine transmembrane transporter activity	2/2411	16/18639	0.125	0.966352136043136	0.631962064001793	0.969642786215674
GO:0043023	ribosomal large subunit binding	2/2411	16/18639	0.125	0.966352136043136	0.631962064001793	0.969642786215674
GO:0008235	metalloexopeptidase activity	8/2411	66/18639	0.121212121212121	0.937068737981222	0.633386806580034	0.969642786215674
GO:0019239	deaminase activity	4/2411	33/18639	0.121212121212121	0.937068737981222	0.633407678335138	0.969642786215674
GO:0030296	protein tyrosine kinase activator activity	4/2411	33/18639	0.121212121212121	0.937068737981222	0.633407678335138	0.969642786215674
GO:0140311	protein sequestering activity	4/2411	33/18639	0.121212121212121	0.937068737981222	0.633407678335138	0.969642786215674
GO:0004386	helicase activity	19/2411	155/18639	0.12258064516129	0.947648546313268	0.635587105565148	0.969642786215674
GO:0004842	ubiquitin-protein transferase activity	56/2411	449/18639	0.124721603563474	0.964199904114309	0.637769005307688	0.969642786215674
GO:0072341	modified amino acid binding	11/2411	91/18639	0.120879120879121	0.934494373316439	0.64229094064491	0.969642786215674
GO:0000030	mannosyltransferase activity	3/2411	25/18639	0.12	0.92769805060141	0.644917923578203	0.969642786215674
GO:0001848	complement binding	3/2411	25/18639	0.12	0.92769805060141	0.644917923578203	0.969642786215674
GO:0005251	delayed rectifier potassium channel activity	3/2411	25/18639	0.12	0.92769805060141	0.644917923578203	0.969642786215674
GO:0015296	monoatomic anion:monoatomic cation symporter activity	3/2411	25/18639	0.12	0.92769805060141	0.644917923578203	0.969642786215674
GO:0015645	fatty acid ligase activity	3/2411	25/18639	0.12	0.92769805060141	0.644917923578203	0.969642786215674
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	3/2411	25/18639	0.12	0.92769805060141	0.644917923578203	0.969642786215674
GO:0017056	structural constituent of nuclear pore	3/2411	25/18639	0.12	0.92769805060141	0.644917923578203	0.969642786215674
GO:0120020	cholesterol transfer activity	3/2411	25/18639	0.12	0.92769805060141	0.644917923578203	0.969642786215674
GO:0120515	fatty acid-CoA ligase activity	3/2411	25/18639	0.12	0.92769805060141	0.644917923578203	0.969642786215674
GO:0008168	methyltransferase activity	25/2411	204/18639	0.122549019607843	0.947404054944251	0.645881781826603	0.969642786215674
GO:0016853	isomerase activity	22/2411	180/18639	0.122222222222222	0.944877644131066	0.646080722291477	0.969642786215674
GO:0140713	histone chaperone activity	20/2411	164/18639	0.121951219512195	0.942782571749401	0.646596711785656	0.969642786215674
GO:0042056	chemoattractant activity	5/2411	42/18639	0.119047619047619	0.920335367660129	0.648012021123307	0.969642786215674
GO:0008173	RNA methyltransferase activity	8/2411	67/18639	0.119402985074627	0.923082637414339	0.650645281342266	0.969642786215674
GO:0015459	potassium channel regulator activity	7/2411	59/18639	0.11864406779661	0.917215586752807	0.655129690790633	0.969642786215674
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	7/2411	59/18639	0.11864406779661	0.917215586752807	0.655129690790633	0.969642786215674
GO:0070063	RNA polymerase binding	7/2411	59/18639	0.11864406779661	0.917215586752807	0.655129690790633	0.969642786215674
GO:0015020	glucuronosyltransferase activity	4/2411	34/18639	0.117647058823529	0.909507892746481	0.657373589573356	0.969642786215674
GO:0030332	cyclin binding	4/2411	34/18639	0.117647058823529	0.909507892746481	0.657373589573356	0.969642786215674
GO:0052866	phosphatidylinositol phosphate phosphatase activity	4/2411	34/18639	0.117647058823529	0.909507892746481	0.657373589573356	0.969642786215674
GO:0180051	translation factor activity	10/2411	84/18639	0.119047619047619	0.920335367660129	0.659712067753004	0.969642786215674
GO:0016597	amino acid binding	6/2411	51/18639	0.117647058823529	0.909507892746481	0.661030918643399	0.969642786215674
GO:0016830	carbon-carbon lyase activity	6/2411	51/18639	0.117647058823529	0.909507892746481	0.661030918643399	0.969642786215674
GO:0051536	iron-sulfur cluster binding	9/2411	76/18639	0.118421052631579	0.915491497304023	0.663141906234964	0.969642786215674
GO:0004549	tRNA-specific ribonuclease activity	2/2411	17/18639	0.117647058823529	0.909507892746481	0.665495943930365	0.969642786215674
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	2/2411	17/18639	0.117647058823529	0.909507892746481	0.665495943930365	0.969642786215674
GO:0016018	cyclosporin A binding	2/2411	17/18639	0.117647058823529	0.909507892746481	0.665495943930365	0.969642786215674
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/2411	17/18639	0.117647058823529	0.909507892746481	0.665495943930365	0.969642786215674
GO:0032183	SUMO binding	2/2411	17/18639	0.117647058823529	0.909507892746481	0.665495943930365	0.969642786215674
GO:0032977	membrane insertase activity	2/2411	17/18639	0.117647058823529	0.909507892746481	0.665495943930365	0.969642786215674
GO:0045125	bioactive lipid receptor activity	2/2411	17/18639	0.117647058823529	0.909507892746481	0.665495943930365	0.969642786215674
GO:0051787	misfolded protein binding	2/2411	17/18639	0.117647058823529	0.909507892746481	0.665495943930365	0.969642786215674
GO:0008375	acetylglucosaminyltransferase activity	5/2411	43/18639	0.116279069767442	0.89893221957501	0.66901379111146	0.969642786215674
GO:0004529	DNA exonuclease activity	3/2411	26/18639	0.115384615384615	0.89201735634751	0.671776413797646	0.969642786215674
GO:0019865	immunoglobulin binding	3/2411	26/18639	0.115384615384615	0.89201735634751	0.671776413797646	0.969642786215674
GO:0003724	RNA helicase activity	9/2411	77/18639	0.116883116883117	0.903601997339036	0.67868115693172	0.969642786215674
GO:0051540	metal cluster binding	9/2411	77/18639	0.116883116883117	0.903601997339036	0.67868115693172	0.969642786215674
GO:0019787	ubiquitin-like protein transferase activity	59/2411	479/18639	0.123173277661795	0.952230079775282	0.678885848809745	0.969642786215674
GO:0016874	ligase activity	20/2411	167/18639	0.119760479041916	0.925846357885639	0.678979278635247	0.969642786215674
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	6/2411	52/18639	0.115384615384615	0.89201735634751	0.679858205773869	0.969642786215674
GO:0034061	DNA polymerase activity	4/2411	35/18639	0.114285714285714	0.883521952953724	0.680258166608746	0.969642786215674
GO:0016410	N-acyltransferase activity	11/2411	94/18639	0.117021276595745	0.90467008480634	0.685193527878004	0.969642786215674
GO:0016755	aminoacyltransferase activity	61/2411	496/18639	0.122983870967742	0.950765811268246	0.685834413469518	0.969642786215674
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	7/2411	61/18639	0.114754098360656	0.88714294456419	0.689987232762523	0.969642786215674
GO:0003689	DNA clamp loader activity	19/2411	160/18639	0.11875	0.918034529240979	0.690798695254774	0.969642786215674
GO:0000400	four-way junction DNA binding	2/2411	18/18639	0.111111111111111	0.858979676482787	0.696516516102368	0.969642786215674
GO:0003746	translation elongation factor activity	2/2411	18/18639	0.111111111111111	0.858979676482787	0.696516516102368	0.969642786215674
GO:0008409	5'-3' exonuclease activity	2/2411	18/18639	0.111111111111111	0.858979676482787	0.696516516102368	0.969642786215674
GO:0015172	acidic amino acid transmembrane transporter activity	2/2411	18/18639	0.111111111111111	0.858979676482787	0.696516516102368	0.969642786215674
GO:0015373	monoatomic anion:sodium symporter activity	2/2411	18/18639	0.111111111111111	0.858979676482787	0.696516516102368	0.969642786215674
GO:0016854	racemase and epimerase activity	2/2411	18/18639	0.111111111111111	0.858979676482787	0.696516516102368	0.969642786215674
GO:0030228	lipoprotein particle receptor activity	2/2411	18/18639	0.111111111111111	0.858979676482787	0.696516516102368	0.969642786215674
GO:0035615	clathrin adaptor activity	2/2411	18/18639	0.111111111111111	0.858979676482787	0.696516516102368	0.969642786215674
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	2/2411	18/18639	0.111111111111111	0.858979676482787	0.696516516102368	0.969642786215674
GO:0098641	cadherin binding involved in cell-cell adhesion	2/2411	18/18639	0.111111111111111	0.858979676482787	0.696516516102368	0.969642786215674
GO:0005104	fibroblast growth factor receptor binding	3/2411	27/18639	0.111111111111111	0.858979676482787	0.697108815175173	0.969642786215674
GO:0016405	CoA-ligase activity	3/2411	27/18639	0.111111111111111	0.858979676482787	0.697108815175173	0.969642786215674
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	3/2411	27/18639	0.111111111111111	0.858979676482787	0.697108815175173	0.969642786215674
GO:0004864	protein phosphatase inhibitor activity	6/2411	53/18639	0.113207547169811	0.87518684019001	0.697993146046644	0.969642786215674
GO:0000993	RNA polymerase II complex binding	4/2411	36/18639	0.111111111111111	0.858979676482787	0.702049771066251	0.969642786215674
GO:0004190	aspartic-type endopeptidase activity	4/2411	36/18639	0.111111111111111	0.858979676482787	0.702049771066251	0.969642786215674
GO:0016409	palmitoyltransferase activity	4/2411	36/18639	0.111111111111111	0.858979676482787	0.702049771066251	0.969642786215674
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	4/2411	36/18639	0.111111111111111	0.858979676482787	0.702049771066251	0.969642786215674
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	4/2411	36/18639	0.111111111111111	0.858979676482787	0.702049771066251	0.969642786215674
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	4/2411	36/18639	0.111111111111111	0.858979676482787	0.702049771066251	0.969642786215674
GO:0008094	ATP-dependent activity, acting on DNA	25/2411	210/18639	0.119047619047619	0.920335367660129	0.703027062773862	0.969642786215674
GO:0015276	ligand-gated monoatomic ion channel activity	22/2411	186/18639	0.118279569892473	0.914397720126838	0.706581766599144	0.969642786215674
GO:0008186	ATP-dependent activity, acting on RNA	9/2411	79/18639	0.113924050632911	0.880725997406402	0.70842336467952	0.969642786215674
GO:0004896	cytokine receptor activity	11/2411	96/18639	0.114583333333333	0.885822791372874	0.712014515876628	0.969642786215674
GO:0140299	molecular sensor activity	8/2411	71/18639	0.112676056338028	0.871077981785362	0.714745813087607	0.969642786215674
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	6/2411	54/18639	0.111111111111111	0.858979676482787	0.715426068041414	0.969642786215674
GO:0004197	cysteine-type endopeptidase activity	10/2411	88/18639	0.113636363636364	0.878501941857396	0.716867145372984	0.969642786215674
GO:0036408	histone H3K14 acetyltransferase activity	3/2411	28/18639	0.107142857142857	0.828301830894116	0.720928132307946	0.969642786215674
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	15/2411	130/18639	0.115384615384615	0.89201735634751	0.721258628424521	0.969642786215674
GO:0022829	wide pore channel activity	4/2411	37/18639	0.108108108108108	0.83576400955082	0.722746539962396	0.969642786215674
GO:0070001	aspartic-type peptidase activity	4/2411	37/18639	0.108108108108108	0.83576400955082	0.722746539962396	0.969642786215674
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	14/2411	122/18639	0.114754098360656	0.88714294456419	0.724523471196703	0.969642786215674
GO:0016918	retinal binding	2/2411	19/18639	0.105263157894737	0.813770219825798	0.725112627668201	0.969642786215674
GO:0022840	leak channel activity	2/2411	19/18639	0.105263157894737	0.813770219825798	0.725112627668201	0.969642786215674
GO:0022842	narrow pore channel activity	2/2411	19/18639	0.105263157894737	0.813770219825798	0.725112627668201	0.969642786215674
GO:0042800	histone H3K4 methyltransferase activity	2/2411	19/18639	0.105263157894737	0.813770219825798	0.725112627668201	0.969642786215674
GO:0070003	threonine-type peptidase activity	2/2411	19/18639	0.105263157894737	0.813770219825798	0.725112627668201	0.969642786215674
GO:0140036	ubiquitin-modified protein reader activity	2/2411	19/18639	0.105263157894737	0.813770219825798	0.725112627668201	0.969642786215674
GO:0022834	ligand-gated channel activity	22/2411	188/18639	0.117021276595745	0.90467008480634	0.725348244028052	0.969642786215674
GO:0140767	enzyme-substrate adaptor activity	16/2411	139/18639	0.115107913669065	0.889878225996557	0.729065381824775	0.969642786215674
GO:0008374	O-acyltransferase activity	6/2411	55/18639	0.109090909090909	0.8433618641831	0.732151749389956	0.969642786215674
GO:0042626	ATPase-coupled transmembrane transporter activity	11/2411	98/18639	0.112244897959184	0.867744775222408	0.737344924816579	0.969642786215674
GO:0004536	DNA nuclease activity	7/2411	64/18639	0.109375	0.845558119037744	0.737837042722579	0.969642786215674
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	15/2411	132/18639	0.113636363636364	0.878501941857396	0.742861621534374	0.969642786215674
GO:0005416	amino acid:monoatomic cation symporter activity	3/2411	29/18639	0.103448275862069	0.799739698794319	0.743260754194226	0.969642786215674
GO:0010484	histone H3 acetyltransferase activity	3/2411	29/18639	0.103448275862069	0.799739698794319	0.743260754194226	0.969642786215674
GO:0035250	UDP-galactosyltransferase activity	3/2411	29/18639	0.103448275862069	0.799739698794319	0.743260754194226	0.969642786215674
GO:0005504	fatty acid binding	5/2411	47/18639	0.106382978723404	0.822427349823945	0.744518767002561	0.969642786215674
GO:0043495	protein-membrane adaptor activity	5/2411	47/18639	0.106382978723404	0.822427349823945	0.744518767002561	0.969642786215674
GO:0061733	protein-lysine-acetyltransferase activity	5/2411	47/18639	0.106382978723404	0.822427349823945	0.744518767002561	0.969642786215674
GO:0061749	forked DNA-dependent helicase activity	5/2411	47/18639	0.106382978723404	0.822427349823945	0.744518767002561	0.969642786215674
GO:0140359	ABC-type transporter activity	5/2411	47/18639	0.106382978723404	0.822427349823945	0.744518767002561	0.969642786215674
GO:1990518	single-stranded 3'-5' DNA helicase activity	5/2411	47/18639	0.106382978723404	0.822427349823945	0.744518767002561	0.969642786215674
GO:0019212	phosphatase inhibitor activity	6/2411	56/18639	0.107142857142857	0.828301830894116	0.748169037293092	0.969642786215674
GO:0030170	pyridoxal phosphate binding	6/2411	56/18639	0.107142857142857	0.828301830894116	0.748169037293092	0.969642786215674
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	6/2411	56/18639	0.107142857142857	0.828301830894116	0.748169037293092	0.969642786215674
GO:0170055	lipid transmembrane transporter activity	6/2411	56/18639	0.107142857142857	0.828301830894116	0.748169037293092	0.969642786215674
GO:0004983	neuropeptide Y receptor activity	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0005131	growth hormone receptor binding	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0005345	purine nucleobase transmembrane transporter activity	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0008190	eukaryotic initiation factor 4E binding	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0008641	ubiquitin-like modifier activating enzyme activity	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0015203	polyamine transmembrane transporter activity	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0015924	mannosyl-oligosaccharide mannosidase activity	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0016303	1-phosphatidylinositol-3-kinase activity	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0019911	structural constituent of myelin sheath	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0030957	Tat protein binding	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0032395	MHC class II receptor activity	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0042166	acetylcholine binding	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0043422	protein kinase B binding	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0045322	unmethylated CpG binding	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0050308	sugar-phosphatase activity	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0050815	phosphoserine residue binding	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0051378	serotonin binding	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0051880	G-quadruplex DNA binding	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0140135	mechanosensitive monoatomic cation channel activity	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0140940	histone H2A methyltransferase activity	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0140999	histone H3K4 trimethyltransferase activity	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0141109	transporter activator activity	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:1905394	retromer complex binding	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:1990259	histone H2AQ104 methyltransferase activity	1/2411	10/18639	0.1	0.773081708834509	0.749811080223124	0.969642786215674
GO:0009055	electron transfer activity	13/2411	116/18639	0.112068965517241	0.866384673693846	0.750875036626308	0.969642786215674
GO:0005326	neurotransmitter transmembrane transporter activity	2/2411	20/18639	0.1	0.773081708834509	0.751392194822039	0.969642786215674
GO:0015095	magnesium ion transmembrane transporter activity	2/2411	20/18639	0.1	0.773081708834509	0.751392194822039	0.969642786215674
GO:0016004	phospholipase activator activity	2/2411	20/18639	0.1	0.773081708834509	0.751392194822039	0.969642786215674
GO:0140664	ATP-dependent DNA damage sensor activity	2/2411	20/18639	0.1	0.773081708834509	0.751392194822039	0.969642786215674
GO:0140104	molecular carrier activity	29/2411	249/18639	0.116465863453815	0.90037628739762	0.755986762653002	0.969642786215674
GO:0003684	damaged DNA binding	8/2411	74/18639	0.108108108108108	0.83576400955082	0.757385863631986	0.969642786215674
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	4/2411	39/18639	0.102564102564103	0.792904316753342	0.760889609081985	0.969642786215674
GO:0009378	four-way junction helicase activity	5/2411	48/18639	0.104166666666667	0.805293446702613	0.761257434236879	0.969642786215674
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	5/2411	48/18639	0.104166666666667	0.805293446702613	0.761257434236879	0.969642786215674
GO:0036121	double-stranded DNA helicase activity	5/2411	48/18639	0.104166666666667	0.805293446702613	0.761257434236879	0.969642786215674
GO:0043138	3'-5' DNA helicase activity	5/2411	48/18639	0.104166666666667	0.805293446702613	0.761257434236879	0.969642786215674
GO:0008135	translation factor activity, RNA binding	9/2411	83/18639	0.108433734939759	0.838281371025371	0.762375893640498	0.969642786215674
GO:0043995	histone H4K5 acetyltransferase activity	3/2411	30/18639	0.1	0.773081708834509	0.764143913495764	0.969642786215674
GO:0043996	histone H4K8 acetyltransferase activity	3/2411	30/18639	0.1	0.773081708834509	0.764143913495764	0.969642786215674
GO:0043997	histone H4K12 acetyltransferase activity	3/2411	30/18639	0.1	0.773081708834509	0.764143913495764	0.969642786215674
GO:0070566	adenylyltransferase activity	3/2411	30/18639	0.1	0.773081708834509	0.764143913495764	0.969642786215674
GO:0004252	serine-type endopeptidase activity	20/2411	176/18639	0.113636363636364	0.878501941857396	0.765604925020174	0.969642786215674
GO:0004620	phospholipase activity	12/2411	109/18639	0.110091743119266	0.851099128992119	0.766758332757415	0.969642786215674
GO:0015078	proton transmembrane transporter activity	21/2411	185/18639	0.113513513513514	0.877552210028361	0.771477144663928	0.969642786215674
GO:0004527	exonuclease activity	9/2411	84/18639	0.107142857142857	0.828301830894116	0.774695552746997	0.969642786215674
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	2/2411	21/18639	0.0952380952380952	0.736268294128103	0.775475787053163	0.969642786215674
GO:0005123	death receptor binding	2/2411	21/18639	0.0952380952380952	0.736268294128103	0.775475787053163	0.969642786215674
GO:0070182	DNA polymerase binding	2/2411	21/18639	0.0952380952380952	0.736268294128103	0.775475787053163	0.969642786215674
GO:0140312	cargo adaptor activity	2/2411	21/18639	0.0952380952380952	0.736268294128103	0.775475787053163	0.969642786215674
GO:0004519	endonuclease activity	14/2411	127/18639	0.110236220472441	0.852216056982923	0.777539531593826	0.969642786215674
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	7/2411	67/18639	0.104477611940299	0.807697307737546	0.780266070685344	0.969642786215674
GO:0000099	sulfur amino acid transmembrane transporter activity	1/2411	11/18639	0.0909090909090909	0.702801553485917	0.782190997855957	0.969642786215674
GO:0001851	complement component C3b binding	1/2411	11/18639	0.0909090909090909	0.702801553485917	0.782190997855957	0.969642786215674
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/2411	11/18639	0.0909090909090909	0.702801553485917	0.782190997855957	0.969642786215674
GO:0005221	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	1/2411	11/18639	0.0909090909090909	0.702801553485917	0.782190997855957	0.969642786215674
GO:0008172	S-methyltransferase activity	1/2411	11/18639	0.0909090909090909	0.702801553485917	0.782190997855957	0.969642786215674
GO:0008199	ferric iron binding	1/2411	11/18639	0.0909090909090909	0.702801553485917	0.782190997855957	0.969642786215674
GO:0015205	nucleobase transmembrane transporter activity	1/2411	11/18639	0.0909090909090909	0.702801553485917	0.782190997855957	0.969642786215674
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	1/2411	11/18639	0.0909090909090909	0.702801553485917	0.782190997855957	0.969642786215674
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	1/2411	11/18639	0.0909090909090909	0.702801553485917	0.782190997855957	0.969642786215674
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	1/2411	11/18639	0.0909090909090909	0.702801553485917	0.782190997855957	0.969642786215674
GO:0032404	mismatch repair complex binding	1/2411	11/18639	0.0909090909090909	0.702801553485917	0.782190997855957	0.969642786215674
GO:0043855	cyclic nucleotide-activated monoatomic ion channel activity	1/2411	11/18639	0.0909090909090909	0.702801553485917	0.782190997855957	0.969642786215674
GO:0070990	snRNP binding	1/2411	11/18639	0.0909090909090909	0.702801553485917	0.782190997855957	0.969642786215674
GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/2411	11/18639	0.0909090909090909	0.702801553485917	0.782190997855957	0.969642786215674
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/2411	11/18639	0.0909090909090909	0.702801553485917	0.782190997855957	0.969642786215674
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	1/2411	11/18639	0.0909090909090909	0.702801553485917	0.782190997855957	0.969642786215674
GO:0005164	tumor necrosis factor receptor binding	3/2411	31/18639	0.0967741935483871	0.748143589194686	0.783623431692272	0.969642786215674
GO:0005184	neuropeptide hormone activity	3/2411	31/18639	0.0967741935483871	0.748143589194686	0.783623431692272	0.969642786215674
GO:0005310	dicarboxylic acid transmembrane transporter activity	3/2411	31/18639	0.0967741935483871	0.748143589194686	0.783623431692272	0.969642786215674
GO:0005452	solute:inorganic anion antiporter activity	3/2411	31/18639	0.0967741935483871	0.748143589194686	0.783623431692272	0.969642786215674
GO:0016878	acid-thiol ligase activity	3/2411	31/18639	0.0967741935483871	0.748143589194686	0.783623431692272	0.969642786215674
GO:0140097	catalytic activity, acting on DNA	39/2411	336/18639	0.116071428571429	0.897326983468626	0.790330082146001	0.969642786215674
GO:0032813	tumor necrosis factor receptor superfamily binding	5/2411	50/18639	0.1	0.773081708834509	0.79222445609335	0.969642786215674
GO:0005506	iron ion binding	17/2411	154/18639	0.11038961038961	0.853401886375756	0.792605119183403	0.969642786215674
GO:0001530	lipopolysaccharide binding	4/2411	41/18639	0.0975609756097561	0.754226057399521	0.794822482929624	0.969642786215674
GO:0016877	ligase activity, forming carbon-sulfur bonds	4/2411	41/18639	0.0975609756097561	0.754226057399521	0.794822482929624	0.969642786215674
GO:0008649	rRNA methyltransferase activity	2/2411	22/18639	0.0909090909090909	0.702801553485917	0.797491551034149	0.969642786215674
GO:0015377	chloride:monoatomic cation symporter activity	2/2411	22/18639	0.0909090909090909	0.702801553485917	0.797491551034149	0.969642786215674
GO:0032931	histone H3K56 acetyltransferase activity	2/2411	22/18639	0.0909090909090909	0.702801553485917	0.797491551034149	0.969642786215674
GO:0043992	histone H3K9 acetyltransferase activity	2/2411	22/18639	0.0909090909090909	0.702801553485917	0.797491551034149	0.969642786215674
GO:0043993	histone H3K18 acetyltransferase activity	2/2411	22/18639	0.0909090909090909	0.702801553485917	0.797491551034149	0.969642786215674
GO:0043994	histone H3K23 acetyltransferase activity	2/2411	22/18639	0.0909090909090909	0.702801553485917	0.797491551034149	0.969642786215674
GO:0043999	histone H2AK5 acetyltransferase activity	2/2411	22/18639	0.0909090909090909	0.702801553485917	0.797491551034149	0.969642786215674
GO:0044012	histone H2AK9 acetyltransferase activity	2/2411	22/18639	0.0909090909090909	0.702801553485917	0.797491551034149	0.969642786215674
GO:0044014	histone H2BK5 acetyltransferase activity	2/2411	22/18639	0.0909090909090909	0.702801553485917	0.797491551034149	0.969642786215674
GO:0044015	histone H2BK12 acetyltransferase activity	2/2411	22/18639	0.0909090909090909	0.702801553485917	0.797491551034149	0.969642786215674
GO:0044016	histone H3K4 acetyltransferase activity	2/2411	22/18639	0.0909090909090909	0.702801553485917	0.797491551034149	0.969642786215674
GO:0044017	histone H3K27 acetyltransferase activity	2/2411	22/18639	0.0909090909090909	0.702801553485917	0.797491551034149	0.969642786215674
GO:0044018	histone H3K36 acetyltransferase activity	2/2411	22/18639	0.0909090909090909	0.702801553485917	0.797491551034149	0.969642786215674
GO:0046972	histone H4K16 acetyltransferase activity	2/2411	22/18639	0.0909090909090909	0.702801553485917	0.797491551034149	0.969642786215674
GO:0140035	ubiquitin-like protein reader activity	2/2411	22/18639	0.0909090909090909	0.702801553485917	0.797491551034149	0.969642786215674
GO:0140908	histone H3K122 acetyltransferase activity	2/2411	22/18639	0.0909090909090909	0.702801553485917	0.797491551034149	0.969642786215674
GO:0008378	galactosyltransferase activity	3/2411	32/18639	0.09375	0.724764102032352	0.801751737719873	0.969642786215674
GO:0015106	bicarbonate transmembrane transporter activity	3/2411	32/18639	0.09375	0.724764102032352	0.801751737719873	0.969642786215674
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	3/2411	32/18639	0.09375	0.724764102032352	0.801751737719873	0.969642786215674
GO:0042910	xenobiotic transmembrane transporter activity	3/2411	32/18639	0.09375	0.724764102032352	0.801751737719873	0.969642786215674
GO:0070717	poly-purine tract binding	3/2411	32/18639	0.09375	0.724764102032352	0.801751737719873	0.969642786215674
GO:0140142	nucleocytoplasmic carrier activity	3/2411	32/18639	0.09375	0.724764102032352	0.801751737719873	0.969642786215674
GO:0160041	neuropeptide activity	3/2411	32/18639	0.09375	0.724764102032352	0.801751737719873	0.969642786215674
GO:0016298	lipase activity	14/2411	130/18639	0.107692307692308	0.832549532591009	0.805733110085785	0.969642786215674
GO:0016798	hydrolase activity, acting on glycosyl bonds	14/2411	130/18639	0.107692307692308	0.832549532591009	0.805733110085785	0.969642786215674
GO:0016859	cis-trans isomerase activity	4/2411	42/18639	0.0952380952380952	0.736268294128103	0.810276215751341	0.969642786215674
GO:0003720	telomerase activity	1/2411	12/18639	0.0833333333333333	0.64423475736209	0.810381759299445	0.969642786215674
GO:0004126	cytidine deaminase activity	1/2411	12/18639	0.0833333333333333	0.64423475736209	0.810381759299445	0.969642786215674
GO:0004300	enoyl-CoA hydratase activity	1/2411	12/18639	0.0833333333333333	0.64423475736209	0.810381759299445	0.969642786215674
GO:0004859	phospholipase inhibitor activity	1/2411	12/18639	0.0833333333333333	0.64423475736209	0.810381759299445	0.969642786215674
GO:0004875	complement receptor activity	1/2411	12/18639	0.0833333333333333	0.64423475736209	0.810381759299445	0.969642786215674
GO:0010853	cyclase activator activity	1/2411	12/18639	0.0833333333333333	0.64423475736209	0.810381759299445	0.969642786215674
GO:0015166	polyol transmembrane transporter activity	1/2411	12/18639	0.0833333333333333	0.64423475736209	0.810381759299445	0.969642786215674
GO:0016273	arginine N-methyltransferase activity	1/2411	12/18639	0.0833333333333333	0.64423475736209	0.810381759299445	0.969642786215674
GO:0016274	protein-arginine N-methyltransferase activity	1/2411	12/18639	0.0833333333333333	0.64423475736209	0.810381759299445	0.969642786215674
GO:0036009	protein-glutamine N-methyltransferase activity	1/2411	12/18639	0.0833333333333333	0.64423475736209	0.810381759299445	0.969642786215674
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	1/2411	12/18639	0.0833333333333333	0.64423475736209	0.810381759299445	0.969642786215674
GO:0070008	serine-type exopeptidase activity	1/2411	12/18639	0.0833333333333333	0.64423475736209	0.810381759299445	0.969642786215674
GO:0070410	co-SMAD binding	1/2411	12/18639	0.0833333333333333	0.64423475736209	0.810381759299445	0.969642786215674
GO:0097677	STAT family protein binding	1/2411	12/18639	0.0833333333333333	0.64423475736209	0.810381759299445	0.969642786215674
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/2411	12/18639	0.0833333333333333	0.64423475736209	0.810381759299445	0.969642786215674
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/2411	12/18639	0.0833333333333333	0.64423475736209	0.810381759299445	0.969642786215674
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/2411	12/18639	0.0833333333333333	0.64423475736209	0.810381759299445	0.969642786215674
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/2411	12/18639	0.0833333333333333	0.64423475736209	0.810381759299445	0.969642786215674
GO:0141221	histone deacetylase activity, hydrolytic mechanism	1/2411	12/18639	0.0833333333333333	0.64423475736209	0.810381759299445	0.969642786215674
GO:1990817	poly(A) RNA polymerase activity	1/2411	12/18639	0.0833333333333333	0.64423475736209	0.810381759299445	0.969642786215674
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	13/2411	122/18639	0.10655737704918	0.823775591381034	0.811026342789849	0.969642786215674
GO:0008028	monocarboxylic acid transmembrane transporter activity	7/2411	70/18639	0.1	0.773081708834509	0.817367291873866	0.969642786215674
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	2/2411	23/18639	0.0869565217391304	0.67224496420392	0.817571235135684	0.969642786215674
GO:0005283	amino acid:sodium symporter activity	2/2411	23/18639	0.0869565217391304	0.67224496420392	0.817571235135684	0.969642786215674
GO:0042171	lysophosphatidic acid acyltransferase activity	2/2411	23/18639	0.0869565217391304	0.67224496420392	0.817571235135684	0.969642786215674
GO:0044013	histone H2B acetyltransferase activity	2/2411	23/18639	0.0869565217391304	0.67224496420392	0.817571235135684	0.969642786215674
GO:0070577	lysine-acetylated histone binding	2/2411	23/18639	0.0869565217391304	0.67224496420392	0.817571235135684	0.969642786215674
GO:0071617	lysophospholipid acyltransferase activity	2/2411	23/18639	0.0869565217391304	0.67224496420392	0.817571235135684	0.969642786215674
GO:0140102	catalytic activity, acting on a rRNA	2/2411	23/18639	0.0869565217391304	0.67224496420392	0.817571235135684	0.969642786215674
GO:0140103	catalytic activity, acting on a glycoprotein	2/2411	23/18639	0.0869565217391304	0.67224496420392	0.817571235135684	0.969642786215674
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	3/2411	33/18639	0.0909090909090909	0.702801553485917	0.818586143658346	0.969642786215674
GO:0016651	oxidoreductase activity, acting on NAD(P)H	9/2411	88/18639	0.102272727272727	0.790651747671656	0.819356040041179	0.969642786215674
GO:0004497	monooxygenase activity	11/2411	106/18639	0.10377358490566	0.802254603507509	0.823431473758172	0.969642786215674
GO:0008170	N-methyltransferase activity	10/2411	98/18639	0.102040816326531	0.788858886565825	0.830750385725506	0.969642786215674
GO:0016860	intramolecular oxidoreductase activity	5/2411	53/18639	0.0943396226415094	0.729322366825008	0.83265993249502	0.969642786215674
GO:0034212	protein N-acetyltransferase activity	5/2411	53/18639	0.0943396226415094	0.729322366825008	0.83265993249502	0.969642786215674
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	5/2411	53/18639	0.0943396226415094	0.729322366825008	0.83265993249502	0.969642786215674
GO:0016831	carboxy-lyase activity	3/2411	34/18639	0.0882352941176471	0.68213091955986	0.834187358569797	0.969642786215674
GO:0019825	oxygen binding	3/2411	34/18639	0.0882352941176471	0.68213091955986	0.834187358569797	0.969642786215674
GO:0015294	solute:monoatomic cation symporter activity	12/2411	116/18639	0.103448275862069	0.799739698794319	0.834541845218234	0.969642786215674
GO:0002161	aminoacyl-tRNA editing activity	1/2411	13/18639	0.0769230769230769	0.594678237565007	0.834925141396886	0.969642786215674
GO:0003964	RNA-directed DNA polymerase activity	1/2411	13/18639	0.0769230769230769	0.594678237565007	0.834925141396886	0.969642786215674
GO:0004535	poly(A)-specific ribonuclease activity	1/2411	13/18639	0.0769230769230769	0.594678237565007	0.834925141396886	0.969642786215674
GO:0004993	G protein-coupled serotonin receptor activity	1/2411	13/18639	0.0769230769230769	0.594678237565007	0.834925141396886	0.969642786215674
GO:0005542	folic acid binding	1/2411	13/18639	0.0769230769230769	0.594678237565007	0.834925141396886	0.969642786215674
GO:0008417	fucosyltransferase activity	1/2411	13/18639	0.0769230769230769	0.594678237565007	0.834925141396886	0.969642786215674
GO:0009982	pseudouridine synthase activity	1/2411	13/18639	0.0769230769230769	0.594678237565007	0.834925141396886	0.969642786215674
GO:0035673	oligopeptide transmembrane transporter activity	1/2411	13/18639	0.0769230769230769	0.594678237565007	0.834925141396886	0.969642786215674
GO:0045159	myosin II binding	1/2411	13/18639	0.0769230769230769	0.594678237565007	0.834925141396886	0.969642786215674
GO:0046975	histone H3K36 methyltransferase activity	1/2411	13/18639	0.0769230769230769	0.594678237565007	0.834925141396886	0.969642786215674
GO:0051011	microtubule minus-end binding	1/2411	13/18639	0.0769230769230769	0.594678237565007	0.834925141396886	0.969642786215674
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/2411	13/18639	0.0769230769230769	0.594678237565007	0.834925141396886	0.969642786215674
GO:0140666	annealing activity	1/2411	13/18639	0.0769230769230769	0.594678237565007	0.834925141396886	0.969642786215674
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/2411	13/18639	0.0769230769230769	0.594678237565007	0.834925141396886	0.969642786215674
GO:0004806	triacylglycerol lipase activity	2/2411	24/18639	0.0833333333333333	0.64423475736209	0.835847114939403	0.969642786215674
GO:0019957	C-C chemokine binding	2/2411	24/18639	0.0833333333333333	0.64423475736209	0.835847114939403	0.969642786215674
GO:0042625	ATPase-coupled ion transmembrane transporter activity	2/2411	24/18639	0.0833333333333333	0.64423475736209	0.835847114939403	0.969642786215674
GO:0043998	histone H2A acetyltransferase activity	2/2411	24/18639	0.0833333333333333	0.64423475736209	0.835847114939403	0.969642786215674
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	2/2411	24/18639	0.0833333333333333	0.64423475736209	0.835847114939403	0.969642786215674
GO:0046961	proton-transporting ATPase activity, rotational mechanism	2/2411	24/18639	0.0833333333333333	0.64423475736209	0.835847114939403	0.969642786215674
GO:0060229	lipase activator activity	2/2411	24/18639	0.0833333333333333	0.64423475736209	0.835847114939403	0.969642786215674
GO:0070840	dynein complex binding	2/2411	24/18639	0.0833333333333333	0.64423475736209	0.835847114939403	0.969642786215674
GO:0140033	acetylation-dependent protein binding	2/2411	24/18639	0.0833333333333333	0.64423475736209	0.835847114939403	0.969642786215674
GO:0043014	alpha-tubulin binding	4/2411	44/18639	0.0909090909090909	0.702801553485917	0.838323773514165	0.971642109463857
GO:1901682	sulfur compound transmembrane transporter activity	6/2411	63/18639	0.0952380952380952	0.736268294128103	0.841041855248852	0.973917408681346
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	5/2411	54/18639	0.0925925925925926	0.715816397068989	0.84462257172498	0.976311037208982
GO:0050661	NADP binding	5/2411	54/18639	0.0925925925925926	0.715816397068989	0.84462257172498	0.976311037208982
GO:0010485	histone H4 acetyltransferase activity	3/2411	35/18639	0.0857142857142857	0.662641464715293	0.848618220316145	0.976673575731354
GO:0016229	steroid dehydrogenase activity	3/2411	35/18639	0.0857142857142857	0.662641464715293	0.848618220316145	0.976673575731354
GO:0042605	peptide antigen binding	4/2411	45/18639	0.0888888888888889	0.68718374118623	0.850991445903468	0.976673575731354
GO:0005537	D-mannose binding	2/2411	25/18639	0.08	0.618465367067607	0.852449653318637	0.976673575731354
GO:0015662	P-type ion transporter activity	2/2411	25/18639	0.08	0.618465367067607	0.852449653318637	0.976673575731354
GO:0140358	P-type transmembrane transporter activity	2/2411	25/18639	0.08	0.618465367067607	0.852449653318637	0.976673575731354
GO:0008494	translation activator activity	1/2411	14/18639	0.0714285714285714	0.552201220596078	0.856292879187722	0.976673575731354
GO:0008559	ABC-type xenobiotic transporter activity	1/2411	14/18639	0.0714285714285714	0.552201220596078	0.856292879187722	0.976673575731354
GO:0015926	glucosidase activity	1/2411	14/18639	0.0714285714285714	0.552201220596078	0.856292879187722	0.976673575731354
GO:0016530	metallochaperone activity	1/2411	14/18639	0.0714285714285714	0.552201220596078	0.856292879187722	0.976673575731354
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/2411	14/18639	0.0714285714285714	0.552201220596078	0.856292879187722	0.976673575731354
GO:0043176	amine binding	1/2411	14/18639	0.0714285714285714	0.552201220596078	0.856292879187722	0.976673575731354
GO:0061665	SUMO ligase activity	1/2411	14/18639	0.0714285714285714	0.552201220596078	0.856292879187722	0.976673575731354
GO:0098847	sequence-specific single stranded DNA binding	1/2411	14/18639	0.0714285714285714	0.552201220596078	0.856292879187722	0.976673575731354
GO:1901612	cardiolipin binding	1/2411	14/18639	0.0714285714285714	0.552201220596078	0.856292879187722	0.976673575731354
GO:0038024	cargo receptor activity	6/2411	65/18639	0.0923076923076923	0.713613885078008	0.861799882569975	0.978304485211899
GO:0055106	ubiquitin-protein transferase regulator activity	3/2411	36/18639	0.0833333333333333	0.64423475736209	0.861942624793408	0.978304485211899
GO:0008143	poly(A) binding	2/2411	26/18639	0.0769230769230769	0.594678237565007	0.867505756612054	0.978304485211899
GO:0005253	monoatomic anion channel activity	10/2411	103/18639	0.0970873786407767	0.750564765858746	0.872634500270136	0.978304485211899
GO:0004540	RNA nuclease activity	12/2411	121/18639	0.0991735537190083	0.766692603802818	0.87295931087672	0.978304485211899
GO:0099095	ligand-gated monoatomic anion channel activity	4/2411	47/18639	0.0851063829787234	0.657941879859156	0.873810541502114	0.978304485211899
GO:0140101	catalytic activity, acting on a tRNA	14/2411	139/18639	0.100719424460432	0.778643447746987	0.874587747633497	0.978304485211899
GO:0004129	cytochrome-c oxidase activity	1/2411	15/18639	0.0666666666666667	0.515387805889672	0.874895717753005	0.978304485211899
GO:0004559	alpha-mannosidase activity	1/2411	15/18639	0.0666666666666667	0.515387805889672	0.874895717753005	0.978304485211899
GO:0008020	G protein-coupled photoreceptor activity	1/2411	15/18639	0.0666666666666667	0.515387805889672	0.874895717753005	0.978304485211899
GO:0010181	FMN binding	1/2411	15/18639	0.0666666666666667	0.515387805889672	0.874895717753005	0.978304485211899
GO:0015250	water channel activity	1/2411	15/18639	0.0666666666666667	0.515387805889672	0.874895717753005	0.978304485211899
GO:0015929	hexosaminidase activity	1/2411	15/18639	0.0666666666666667	0.515387805889672	0.874895717753005	0.978304485211899
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/2411	15/18639	0.0666666666666667	0.515387805889672	0.874895717753005	0.978304485211899
GO:0017081	chloride channel regulator activity	1/2411	15/18639	0.0666666666666667	0.515387805889672	0.874895717753005	0.978304485211899
GO:0033130	acetylcholine receptor binding	1/2411	15/18639	0.0666666666666667	0.515387805889672	0.874895717753005	0.978304485211899
GO:0042809	nuclear vitamin D receptor binding	1/2411	15/18639	0.0666666666666667	0.515387805889672	0.874895717753005	0.978304485211899
GO:0050700	CARD domain binding	1/2411	15/18639	0.0666666666666667	0.515387805889672	0.874895717753005	0.978304485211899
GO:0050780	dopamine receptor binding	1/2411	15/18639	0.0666666666666667	0.515387805889672	0.874895717753005	0.978304485211899
GO:0055105	ubiquitin-protein transferase inhibitor activity	1/2411	15/18639	0.0666666666666667	0.515387805889672	0.874895717753005	0.978304485211899
GO:0140161	monocarboxylate:sodium symporter activity	1/2411	15/18639	0.0666666666666667	0.515387805889672	0.874895717753005	0.978304485211899
GO:0016504	peptidase activator activity	5/2411	57/18639	0.087719298245614	0.678141849854832	0.876327390608651	0.978304485211899
GO:0004518	nuclease activity	22/2411	209/18639	0.105263157894737	0.813770219825798	0.876378258735114	0.978304485211899
GO:0008528	G protein-coupled peptide receptor activity	12/2411	122/18639	0.0983606557377049	0.760408238197877	0.879715634668014	0.978304485211899
GO:0005044	scavenger receptor activity	2/2411	27/18639	0.0740740740740741	0.572653117655191	0.881137511927004	0.978304485211899
GO:0008266	poly(U) RNA binding	2/2411	27/18639	0.0740740740740741	0.572653117655191	0.881137511927004	0.978304485211899
GO:0008320	protein transmembrane transporter activity	2/2411	27/18639	0.0740740740740741	0.572653117655191	0.881137511927004	0.978304485211899
GO:0008395	steroid hydroxylase activity	2/2411	27/18639	0.0740740740740741	0.572653117655191	0.881137511927004	0.978304485211899
GO:0023026	MHC class II protein complex binding	2/2411	27/18639	0.0740740740740741	0.572653117655191	0.881137511927004	0.978304485211899
GO:0008509	monoatomic anion transmembrane transporter activity	15/2411	149/18639	0.100671140939597	0.778270176679035	0.881786573384431	0.978304485211899
GO:0042162	telomeric DNA binding	3/2411	38/18639	0.0789473684210526	0.610327664869349	0.885527731301492	0.978304485211899
GO:0008408	3'-5' exonuclease activity	5/2411	58/18639	0.0862068965517241	0.666449748995266	0.885594889201231	0.978304485211899
GO:0017116	single-stranded DNA helicase activity	5/2411	58/18639	0.0862068965517241	0.666449748995266	0.885594889201231	0.978304485211899
GO:0016407	acetyltransferase activity	9/2411	96/18639	0.09375	0.724764102032352	0.887967592240345	0.978304485211899
GO:0000062	fatty-acyl-CoA binding	1/2411	16/18639	0.0625	0.483176068021568	0.891091294669753	0.978304485211899
GO:0003688	DNA replication origin binding	1/2411	16/18639	0.0625	0.483176068021568	0.891091294669753	0.978304485211899
GO:0005521	lamin binding	1/2411	16/18639	0.0625	0.483176068021568	0.891091294669753	0.978304485211899
GO:0015923	mannosidase activity	1/2411	16/18639	0.0625	0.483176068021568	0.891091294669753	0.978304485211899
GO:0016675	oxidoreductase activity, acting on a heme group of donors	1/2411	16/18639	0.0625	0.483176068021568	0.891091294669753	0.978304485211899
GO:0017070	U6 snRNA binding	1/2411	16/18639	0.0625	0.483176068021568	0.891091294669753	0.978304485211899
GO:0019841	retinol binding	1/2411	16/18639	0.0625	0.483176068021568	0.891091294669753	0.978304485211899
GO:0022841	potassium ion leak channel activity	1/2411	16/18639	0.0625	0.483176068021568	0.891091294669753	0.978304485211899
GO:0097027	ubiquitin-protein transferase activator activity	1/2411	16/18639	0.0625	0.483176068021568	0.891091294669753	0.978304485211899
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	1/2411	16/18639	0.0625	0.483176068021568	0.891091294669753	0.978304485211899
GO:0019789	SUMO transferase activity	2/2411	28/18639	0.0714285714285714	0.552201220596078	0.893461310359239	0.980072355751206
GO:0000217	DNA secondary structure binding	3/2411	39/18639	0.0769230769230769	0.594678237565007	0.89591424148645	0.981846940118443
GO:0098960	postsynaptic neurotransmitter receptor activity	6/2411	69/18639	0.0869565217391304	0.67224496420392	0.89660131430971	0.981846940118443
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	5/2411	60/18639	0.0833333333333333	0.64423475736209	0.902351531244279	0.982825873548264
GO:0004181	metallocarboxypeptidase activity	2/2411	29/18639	0.0689655172413793	0.533159799196213	0.904587277482574	0.982825873548264
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	1/2411	17/18639	0.0588235294117647	0.45475394637324	0.905191004090964	0.982825873548264
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	1/2411	17/18639	0.0588235294117647	0.45475394637324	0.905191004090964	0.982825873548264
GO:0036041	long-chain fatty acid binding	1/2411	17/18639	0.0588235294117647	0.45475394637324	0.905191004090964	0.982825873548264
GO:0070402	NADPH binding	1/2411	17/18639	0.0588235294117647	0.45475394637324	0.905191004090964	0.982825873548264
GO:1901567	fatty acid derivative binding	1/2411	17/18639	0.0588235294117647	0.45475394637324	0.905191004090964	0.982825873548264
GO:0004532	RNA exonuclease activity	3/2411	40/18639	0.075	0.579811281625881	0.9054448380335	0.982825873548264
GO:0071855	neuropeptide receptor binding	3/2411	40/18639	0.075	0.579811281625881	0.9054448380335	0.982825873548264
GO:0000049	tRNA binding	7/2411	80/18639	0.0875	0.676446495230195	0.906650197928672	0.982825873548264
GO:0016779	nucleotidyltransferase activity	13/2411	136/18639	0.0955882352941176	0.738975162856515	0.908780501016111	0.982825873548264
GO:0042169	SH2 domain binding	3/2411	41/18639	0.0731707317073171	0.56566954304964	0.91417818185749	0.982825873548264
GO:0140318	protein transporter activity	3/2411	41/18639	0.0731707317073171	0.56566954304964	0.91417818185749	0.982825873548264
GO:0001653	peptide receptor activity	12/2411	128/18639	0.09375	0.724764102032352	0.9143839203918	0.982825873548264
GO:0008187	poly-pyrimidine tract binding	2/2411	30/18639	0.0666666666666667	0.515387805889672	0.914618946338774	0.982825873548264
GO:0005372	water transmembrane transporter activity	1/2411	18/18639	0.0555555555555556	0.429489838241394	0.917465973972647	0.982825873548264
GO:0032393	MHC class I receptor activity	1/2411	18/18639	0.0555555555555556	0.429489838241394	0.917465973972647	0.982825873548264
GO:0034185	apolipoprotein binding	1/2411	18/18639	0.0555555555555556	0.429489838241394	0.917465973972647	0.982825873548264
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/2411	18/18639	0.0555555555555556	0.429489838241394	0.917465973972647	0.982825873548264
GO:1990381	ubiquitin-specific protease binding	1/2411	18/18639	0.0555555555555556	0.429489838241394	0.917465973972647	0.982825873548264
GO:0015103	inorganic anion transmembrane transporter activity	16/2411	165/18639	0.096969696969697	0.749654990384978	0.917871515843482	0.982825873548264
GO:0015399	primary active transmembrane transporter activity	16/2411	166/18639	0.0963855421686747	0.745138996466996	0.922079436436115	0.982825873548264
GO:0004402	histone acetyltransferase activity	3/2411	42/18639	0.0714285714285714	0.552201220596078	0.922170640788732	0.982825873548264
GO:0004520	DNA endonuclease activity	3/2411	42/18639	0.0714285714285714	0.552201220596078	0.922170640788732	0.982825873548264
GO:0048487	beta-tubulin binding	3/2411	42/18639	0.0714285714285714	0.552201220596078	0.922170640788732	0.982825873548264
GO:0022824	transmitter-gated monoatomic ion channel activity	5/2411	63/18639	0.0793650793650794	0.613556911773419	0.923470808619222	0.982825873548264
GO:0022835	transmitter-gated channel activity	5/2411	63/18639	0.0793650793650794	0.613556911773419	0.923470808619222	0.982825873548264
GO:0016411	acylglycerol O-acyltransferase activity	2/2411	31/18639	0.0645161290322581	0.498762392796457	0.923653119762671	0.982825873548264
GO:0047499	calcium-independent phospholipase A2 activity	2/2411	31/18639	0.0645161290322581	0.498762392796457	0.923653119762671	0.982825873548264
GO:0005544	calcium-dependent phospholipid binding	4/2411	53/18639	0.0754716981132075	0.583457893460006	0.925031188302263	0.982825873548264
GO:0016251	RNA polymerase II general transcription initiation factor activity	4/2411	53/18639	0.0754716981132075	0.583457893460006	0.925031188302263	0.982825873548264
GO:0003756	protein disulfide isomerase activity	1/2411	19/18639	0.0526315789473684	0.406885109912899	0.92815227098956	0.982825873548264
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	1/2411	19/18639	0.0526315789473684	0.406885109912899	0.92815227098956	0.982825873548264
GO:0008301	DNA binding, bending	1/2411	19/18639	0.0526315789473684	0.406885109912899	0.92815227098956	0.982825873548264
GO:0008381	mechanosensitive monoatomic ion channel activity	1/2411	19/18639	0.0526315789473684	0.406885109912899	0.92815227098956	0.982825873548264
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	1/2411	19/18639	0.0526315789473684	0.406885109912899	0.92815227098956	0.982825873548264
GO:0034987	immunoglobulin receptor binding	1/2411	19/18639	0.0526315789473684	0.406885109912899	0.92815227098956	0.982825873548264
GO:0042834	peptidoglycan binding	1/2411	19/18639	0.0526315789473684	0.406885109912899	0.92815227098956	0.982825873548264
GO:0099589	serotonin receptor activity	1/2411	19/18639	0.0526315789473684	0.406885109912899	0.92815227098956	0.982825873548264
GO:0120227	acyl-CoA binding	1/2411	19/18639	0.0526315789473684	0.406885109912899	0.92815227098956	0.982825873548264
GO:0003678	DNA helicase activity	6/2411	74/18639	0.0810810810810811	0.626823007163115	0.929313502278207	0.982825873548264
GO:0022884	macromolecule transmembrane transporter activity	2/2411	32/18639	0.0625	0.483176068021568	0.931779878565524	0.982825873548264
GO:0030515	snoRNA binding	2/2411	32/18639	0.0625	0.483176068021568	0.931779878565524	0.982825873548264
GO:0031369	translation initiation factor binding	2/2411	32/18639	0.0625	0.483176068021568	0.931779878565524	0.982825873548264
GO:0047498	calcium-dependent phospholipase A2 activity	2/2411	32/18639	0.0625	0.483176068021568	0.931779878565524	0.982825873548264
GO:0019843	rRNA binding	5/2411	65/18639	0.0769230769230769	0.594678237565007	0.935197508070361	0.984786244651561
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	1/2411	20/18639	0.05	0.386540854417254	0.937455432893114	0.984786244651561
GO:0016408	C-acyltransferase activity	1/2411	20/18639	0.05	0.386540854417254	0.937455432893114	0.984786244651561
GO:0016505	peptidase activator activity involved in apoptotic process	1/2411	20/18639	0.05	0.386540854417254	0.937455432893114	0.984786244651561
GO:0140939	histone H4 methyltransferase activity	1/2411	20/18639	0.05	0.386540854417254	0.937455432893114	0.984786244651561
GO:0042923	neuropeptide binding	2/2411	33/18639	0.0606060606060606	0.468534368990611	0.939082700172439	0.985692988789623
GO:0015035	protein-disulfide reductase activity	2/2411	34/18639	0.0588235294117647	0.45475394637324	0.945638659022604	0.989420681010636
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	3/2411	46/18639	0.0652173913043478	0.50418372315294	0.94776923840871	0.989420681010636
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	5/2411	68/18639	0.0735294117647059	0.56844243296655	0.94977908714695	0.989420681010636
GO:0140375	immune receptor activity	14/2411	156/18639	0.0897435897435897	0.693791277159174	0.951151126741751	0.989420681010636
GO:0000175	3'-5'-RNA exonuclease activity	2/2411	35/18639	0.0571428571428571	0.441760976476862	0.951518685610874	0.989420681010636
GO:0004623	phospholipase A2 activity	2/2411	35/18639	0.0571428571428571	0.441760976476862	0.951518685610874	0.989420681010636
GO:0005343	organic acid:sodium symporter activity	2/2411	35/18639	0.0571428571428571	0.441760976476862	0.951518685610874	0.989420681010636
GO:0015370	solute:sodium symporter activity	6/2411	79/18639	0.0759493670886076	0.587150664937601	0.952528488810144	0.989420681010636
GO:0008970	phospholipase A1 activity	1/2411	22/18639	0.0454545454545455	0.351400776742958	0.952605027763729	0.989420681010636
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	1/2411	22/18639	0.0454545454545455	0.351400776742958	0.952605027763729	0.989420681010636
GO:0034062	5'-3' RNA polymerase activity	1/2411	22/18639	0.0454545454545455	0.351400776742958	0.952605027763729	0.989420681010636
GO:0061133	endopeptidase activator activity	1/2411	22/18639	0.0454545454545455	0.351400776742958	0.952605027763729	0.989420681010636
GO:0097747	RNA polymerase activity	1/2411	22/18639	0.0454545454545455	0.351400776742958	0.952605027763729	0.989420681010636
GO:0008080	N-acetyltransferase activity	5/2411	69/18639	0.072463768115942	0.5602041368366	0.95393360064986	0.990003495445148
GO:0008188	neuropeptide receptor activity	3/2411	48/18639	0.0625	0.483176068021568	0.957396492478932	0.991228946283984
GO:0008171	O-methyltransferase activity	1/2411	23/18639	0.0434782608695652	0.33612248210196	0.95874292742864	0.991228946283984
GO:0016917	GABA receptor activity	1/2411	23/18639	0.0434782608695652	0.33612248210196	0.95874292742864	0.991228946283984
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	1/2411	23/18639	0.0434782608695652	0.33612248210196	0.95874292742864	0.991228946283984
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	7/2411	91/18639	0.0769230769230769	0.594678237565007	0.958956375939854	0.991228946283984
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	4/2411	60/18639	0.0666666666666667	0.515387805889672	0.960603517640082	0.992021926637024
GO:0023023	MHC protein complex binding	2/2411	37/18639	0.0540540540540541	0.41788200477541	0.961505764709273	0.992021926637024
GO:0020037	heme binding	12/2411	142/18639	0.0845070422535211	0.653308486339021	0.964055239393338	0.992021926637024
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/2411	24/18639	0.0416666666666667	0.322117378681045	0.964086223623824	0.992021926637024
GO:0140098	catalytic activity, acting on RNA	39/2411	387/18639	0.10077519379845	0.779074590298342	0.965126789975441	0.992021926637024
GO:0005109	frizzled binding	2/2411	38/18639	0.0526315789473684	0.406885109912899	0.965726766565261	0.992021926637024
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	2/2411	38/18639	0.0526315789473684	0.406885109912899	0.965726766565261	0.992021926637024
GO:0005254	chloride channel activity	6/2411	83/18639	0.072289156626506	0.558854247350247	0.965875612291552	0.992021926637024
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	5/2411	73/18639	0.0684931506849315	0.529508019749663	0.967597728325154	0.992620275487868
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/2411	25/18639	0.04	0.309232683533803	0.96873774738654	0.992620275487868
GO:0003743	translation initiation factor activity	3/2411	51/18639	0.0588235294117647	0.45475394637324	0.968766609952888	0.992620275487868
GO:0008198	ferrous iron binding	1/2411	26/18639	0.0384615384615385	0.297339118782503	0.97278702701752	0.993251175704755
GO:0015036	disulfide oxidoreductase activity	2/2411	40/18639	0.05	0.386540854417254	0.972871762808259	0.993251175704755
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	2/2411	40/18639	0.05	0.386540854417254	0.972871762808259	0.993251175704755
GO:0030594	neurotransmitter receptor activity	7/2411	97/18639	0.0721649484536082	0.557894016684697	0.974587703186156	0.993251175704755
GO:0022853	active monoatomic ion transmembrane transporter activity	9/2411	118/18639	0.076271186440678	0.589638591483947	0.975567902654583	0.993251175704755
GO:0004812	aminoacyl-tRNA ligase activity	2/2411	41/18639	0.0487804878048781	0.37711302869976	0.975881690036503	0.993251175704755
GO:0008137	NADH dehydrogenase (ubiquinone) activity	2/2411	41/18639	0.0487804878048781	0.37711302869976	0.975881690036503	0.993251175704755
GO:0016875	ligase activity, forming carbon-oxygen bonds	2/2411	41/18639	0.0487804878048781	0.37711302869976	0.975881690036503	0.993251175704755
GO:0015252	proton channel activity	1/2411	27/18639	0.037037037037037	0.286326558827596	0.976312008367155	0.993251175704755
GO:0031492	nucleosomal DNA binding	2/2411	42/18639	0.0476190476190476	0.368134147064052	0.978567242498892	0.993383851219095
GO:0051537	2 iron, 2 sulfur cluster binding	1/2411	28/18639	0.0357142857142857	0.276100610298039	0.979380552737818	0.993383851219095
GO:0097718	disordered domain specific binding	1/2411	28/18639	0.0357142857142857	0.276100610298039	0.979380552737818	0.993383851219095
GO:0015108	chloride transmembrane transporter activity	9/2411	121/18639	0.0743801652892562	0.575019452852114	0.980546844003215	0.993383851219095
GO:0046906	tetrapyrrole binding	12/2411	152/18639	0.0789473684210526	0.610327664869349	0.981737432651265	0.993383851219095
GO:0005179	hormone activity	10/2411	132/18639	0.0757575757575758	0.585667961238264	0.981738270261185	0.993383851219095
GO:0140223	general transcription initiation factor activity	4/2411	68/18639	0.0588235294117647	0.45475394637324	0.981832876204919	0.993383851219095
GO:0003954	NADH dehydrogenase activity	2/2411	44/18639	0.0454545454545455	0.351400776742958	0.983096035917514	0.99388235606081
GO:0008106	alcohol dehydrogenase (NADP+) activity	1/2411	30/18639	0.0333333333333333	0.257693902944836	0.984377009926033	0.994398075806251
GO:0036002	pre-mRNA binding	3/2411	59/18639	0.0508474576271186	0.393092394322631	0.98668466725229	0.995949312015222
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	1/2411	34/18639	0.0294117647058824	0.22737697318662	0.991031976315039	0.999555316220798
GO:0004033	aldo-keto reductase (NADPH) activity	1/2411	36/18639	0.0277777777777778	0.214744919120697	0.993205739531557	0.999999999999934
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/2411	36/18639	0.0277777777777778	0.214744919120697	0.993205739531557	0.999999999999934
GO:0030280	structural constituent of skin epidermis	1/2411	37/18639	0.027027027027027	0.208941002387705	0.994086294387732	0.999999999999934
GO:0017069	snRNA binding	2/2411	54/18639	0.037037037037037	0.286326558827596	0.994951876592374	0.999999999999934
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	2/2411	58/18639	0.0344827586206897	0.266579899598106	0.996913000827544	0.999999999999934
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/2411	43/18639	0.0232558139534884	0.179786443915002	0.997429061200485	0.999999999999934
GO:0003730	mRNA 3'-UTR binding	16/2411	262/18639	0.0610687022900763	0.472110967227181	0.999905648261155	0.999999999999934
GO:0003823	antigen binding	6/2411	174/18639	0.0344827586206897	0.266579899598106	0.999996455797363	0.999999999999934
GO:0003735	structural constituent of ribosome	5/2411	175/18639	0.0285714285714286	0.220880488238431	0.999999409330767	0.999999999999934
GO:0030371	translation repressor activity	7/2411	329/18639	0.0212765957446809	0.164485469964789	0.999999999999759	0.999999999999934
GO:0045182	translation regulator activity	8/2411	356/18639	0.0224719101123595	0.173726226704384	0.999999999999934	0.999999999999934