ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0004674	protein serine/threonine kinase activity	163/4208	433/18639	0.376443418013857	1.66742606187269	5.91009239652505e-13	8.06136602886017e-10
GO:0106310	protein serine kinase activity	140/4208	361/18639	0.38781163434903	1.71778066840104	2.0254670671114e-12	1.38136853976998e-09
GO:0003725	double-stranded RNA binding	45/4208	75/18639	0.6	2.65765209125475	3.25350596654076e-12	1.4792607127872e-09
GO:0045296	cadherin binding	127/4208	334/18639	0.380239520958084	1.68424059675326	9.93715611890031e-11	3.388570236545e-08
GO:0003712	transcription coregulator activity	172/4208	495/18639	0.347474747474747	1.53911164880747	2.76669301549873e-10	7.54753854628052e-08
GO:0016922	nuclear receptor binding	62/4208	137/18639	0.452554744525547	2.00455510532597	3.28946389072469e-09	7.47804791158081e-07
GO:0035591	signaling adaptor activity	59/4208	129/18639	0.457364341085271	2.02585882925104	4.79615748309396e-09	9.34565543848594e-07
GO:0031072	heat shock protein binding	59/4208	131/18639	0.450381679389313	1.99492968681973	9.75475552239348e-09	1.50244493404031e-06
GO:0004677	DNA-dependent protein kinase activity	94/4208	246/18639	0.382113821138211	1.69254265974219	1.96735191161043e-08	1.50244493404031e-06
GO:0140857	histone H3T45 kinase activity	94/4208	246/18639	0.382113821138211	1.69254265974219	1.96735191161043e-08	1.50244493404031e-06
GO:0035403	histone H3T6 kinase activity	94/4208	247/18639	0.380566801619433	1.68569026031003	2.47913535561272e-08	1.50244493404031e-06
GO:0003779	actin binding	150/4208	443/18639	0.338600451467269	1.49980366323632	2.65633754376543e-08	1.50244493404031e-06
GO:0004679	AMP-activated protein kinase activity	94/4208	248/18639	0.379032258064516	1.67889312216362	3.11637220877791e-08	1.50244493404031e-06
GO:0004676	3-phosphoinositide-dependent protein kinase activity	93/4208	245/18639	0.379591836734694	1.68137173120199	3.3900910787333e-08	1.50244493404031e-06
GO:0004711	ribosomal protein S6 kinase activity	93/4208	245/18639	0.379591836734694	1.68137173120199	3.3900910787333e-08	1.50244493404031e-06
GO:0035175	histone H3S10 kinase activity	93/4208	245/18639	0.379591836734694	1.68137173120199	3.3900910787333e-08	1.50244493404031e-06
GO:0035979	histone H2AXS139 kinase activity	93/4208	245/18639	0.379591836734694	1.68137173120199	3.3900910787333e-08	1.50244493404031e-06
GO:0044022	histone H3S28 kinase activity	93/4208	245/18639	0.379591836734694	1.68137173120199	3.3900910787333e-08	1.50244493404031e-06
GO:0044023	histone H4S1 kinase activity	93/4208	245/18639	0.379591836734694	1.68137173120199	3.3900910787333e-08	1.50244493404031e-06
GO:0044024	histone H2AS1 kinase activity	93/4208	245/18639	0.379591836734694	1.68137173120199	3.3900910787333e-08	1.50244493404031e-06
GO:0044025	histone H2BS14 kinase activity	93/4208	245/18639	0.379591836734694	1.68137173120199	3.3900910787333e-08	1.50244493404031e-06
GO:0072354	histone H3T3 kinase activity	93/4208	245/18639	0.379591836734694	1.68137173120199	3.3900910787333e-08	1.50244493404031e-06
GO:0072371	histone H2AS121 kinase activity	93/4208	245/18639	0.379591836734694	1.68137173120199	3.3900910787333e-08	1.50244493404031e-06
GO:0072518	Rho-dependent protein serine/threonine kinase activity	93/4208	245/18639	0.379591836734694	1.68137173120199	3.3900910787333e-08	1.50244493404031e-06
GO:0140823	histone H2BS36 kinase activity	93/4208	245/18639	0.379591836734694	1.68137173120199	3.3900910787333e-08	1.50244493404031e-06
GO:0140855	histone H3S57 kinase activity	93/4208	245/18639	0.379591836734694	1.68137173120199	3.3900910787333e-08	1.50244493404031e-06
GO:0140995	histone H2A kinase activity	93/4208	245/18639	0.379591836734694	1.68137173120199	3.3900910787333e-08	1.50244493404031e-06
GO:0140997	histone H4 kinase activity	93/4208	245/18639	0.379591836734694	1.68137173120199	3.3900910787333e-08	1.50244493404031e-06
GO:0140998	histone H2B kinase activity	93/4208	245/18639	0.379591836734694	1.68137173120199	3.3900910787333e-08	1.50244493404031e-06
GO:1990244	histone H2AT120 kinase activity	93/4208	245/18639	0.379591836734694	1.68137173120199	3.3900910787333e-08	1.50244493404031e-06
GO:0140297	DNA-binding transcription factor binding	162/4208	488/18639	0.331967213114754	1.47042226360406	3.41464757736434e-08	1.50244493404031e-06
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	92/4208	243/18639	0.378600823045267	1.67698211519504	4.63125564231875e-08	1.92023221664732e-06
GO:0044389	ubiquitin-like protein ligase binding	115/4208	322/18639	0.357142857142857	1.58193576860402	4.6457231047919e-08	1.92023221664732e-06
GO:0035402	histone H3T11 kinase activity	93/4208	247/18639	0.376518218623482	1.66775738520035	5.32726663226252e-08	2.13717402541355e-06
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	122/4208	349/18639	0.349570200573066	1.54839329098892	7.30918104713092e-08	2.84849227093902e-06
GO:0140996	histone H3 kinase activity	124/4208	357/18639	0.34733893557423	1.53851008083842	8.62671091877124e-08	3.26856491477888e-06
GO:0141003	histone H2AX kinase activity	123/4208	354/18639	0.347457627118644	1.53903581555713	9.50517905061206e-08	3.50407141217158e-06
GO:0031625	ubiquitin protein ligase binding	108/4208	302/18639	0.357615894039735	1.58403104776773	1.09078781042216e-07	3.91535414056798e-06
GO:0003924	GTPase activity	116/4208	331/18639	0.350453172205438	1.55230434333107	1.30323893264111e-07	4.55799462595506e-06
GO:0035173	histone kinase activity	124/4208	360/18639	0.344444444444444	1.5256891634981	1.46150808851084e-07	4.98374258182195e-06
GO:0140272	exogenous protein binding	40/4208	82/18639	0.48780487804878	2.16069275711769	1.64738030527187e-07	5.4805530155874e-06
GO:0001618	virus receptor activity	39/4208	81/18639	0.481481481481481	2.13268377693283	3.61334674309034e-07	1.17347737085124e-05
GO:0140375	immune receptor activity	63/4208	156/18639	0.403846153846154	1.7888042921907	4.36838563418547e-07	1.38569255930907e-05
GO:0001217	DNA-binding transcription repressor activity	99/4208	278/18639	0.356115107913669	1.57738343545696	4.54839040282635e-07	1.41000102487617e-05
GO:0051087	protein-folding chaperone binding	56/4208	134/18639	0.417910447761194	1.85110095908291	5.03463895159338e-07	1.52605500666075e-05
GO:0005543	phospholipid binding	159/4208	497/18639	0.319919517102616	1.41705795610163	6.32182446550505e-07	1.87455838498889e-05
GO:0001221	transcription coregulator binding	49/4208	115/18639	0.426086956521739	1.88731815176062	1.29187317485138e-06	3.74918087339848e-05
GO:0023023	MHC protein complex binding	22/4208	37/18639	0.594594594594595	2.63370927962183	1.45302929418738e-06	4.12902491098248e-05
GO:0043130	ubiquitin binding	44/4208	100/18639	0.44	1.94894486692015	1.55421515059072e-06	4.32642748041987e-05
GO:0042605	peptide antigen binding	25/4208	45/18639	0.555555555555556	2.46078897338403	1.63334729627867e-06	4.4557714242482e-05
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	94/4208	268/18639	0.350746268656716	1.55360259065887	1.87249852250353e-06	5.00801565626433e-05
GO:0060590	ATPase regulator activity	26/4208	49/18639	0.530612244897959	2.3503045704974	3.24528291887853e-06	8.51262673336599e-05
GO:0030695	GTPase regulator activity	153/4208	489/18639	0.312883435582822	1.3858921948261	4.22352826963592e-06	0.000108696086033649
GO:0019207	kinase regulator activity	98/4208	287/18639	0.341463414634146	1.51248492998238	4.36246660456161e-06	0.000110192674974482
GO:0060589	nucleoside-triphosphatase regulator activity	153/4208	490/18639	0.312244897959184	1.38306384340809	4.79193513421582e-06	0.000118839991328552
GO:0003713	transcription coactivator activity	89/4208	256/18639	0.34765625	1.53991559975048	5.22629076987224e-06	0.000127297510894745
GO:0019902	phosphatase binding	70/4208	190/18639	0.368421052631579	1.63189163498099	5.49087837771963e-06	0.000130505662305282
GO:0032182	ubiquitin-like protein binding	49/4208	120/18639	0.408333333333333	1.80867989543726	5.54936100711609e-06	0.000130505662305282
GO:0019001	guanyl nucleotide binding	128/4208	400/18639	0.32	1.4174144486692	7.49694199152281e-06	0.000170430481273952
GO:0032561	guanyl ribonucleotide binding	128/4208	400/18639	0.32	1.4174144486692	7.49694199152281e-06	0.000170430481273952
GO:0023026	MHC class II protein complex binding	17/4208	27/18639	0.62962962962963	2.78889416983523	7.83497196534749e-06	0.000174632445531361
GO:0015291	secondary active transmembrane transporter activity	97/4208	287/18639	0.337979094076655	1.49705141028868	7.93783843324367e-06	0.000174632445531361
GO:0019209	kinase activator activity	57/4208	148/18639	0.385135135135135	1.70592532884596	8.61298501326605e-06	0.000186477961239601
GO:0044183	protein folding chaperone	34/4208	75/18639	0.453333333333333	2.00800380228137	1.05914692153763e-05	0.000225730687652708
GO:0051020	GTPase binding	104/4208	315/18639	0.33015873015873	1.46241173275394	1.20661021048715e-05	0.000253202511862226
GO:0005525	GTP binding	121/4208	378/18639	0.32010582010582	1.41788317037842	1.29226949964188e-05	0.000267069029925989
GO:0004197	cysteine-type endopeptidase activity	38/4208	88/18639	0.431818181818182	1.91270415658486	1.33226647800415e-05	0.000271225593432487
GO:0035259	nuclear glucocorticoid receptor binding	10/4208	12/18639	0.833333333333333	3.69118346007605	1.42428366552845e-05	0.000285694547026589
GO:0046332	SMAD binding	35/4208	79/18639	0.443037974683544	1.96240133320499	1.46956663316993e-05	0.000290505635890404
GO:0019903	protein phosphatase binding	55/4208	144/18639	0.381944444444444	1.69179241920152	1.62831031738743e-05	0.000317287896130923
GO:0015631	tubulin binding	122/4208	385/18639	0.316883116883117	1.40360846377957	2.01356240351167e-05	0.000386830861745059
GO:0002020	protease binding	52/4208	136/18639	0.382352941176471	1.69360182285842	2.64224449233239e-05	0.000500558539936303
GO:0019887	protein kinase regulator activity	86/4208	255/18639	0.337254901960784	1.49384365913666	2.75811920566707e-05	0.000509068865449983
GO:0035091	phosphatidylinositol binding	94/4208	284/18639	0.330985915492958	1.46607568414288	2.77129430010783e-05	0.000509068865449983
GO:0005085	guanyl-nucleotide exchange factor activity	79/4208	230/18639	0.343478260869565	1.52140953050091	2.79913232468833e-05	0.000509068865449983
GO:0051015	actin filament binding	73/4208	209/18639	0.349282296650718	1.5471180435534	2.94879928910834e-05	0.000529231872413655
GO:0042277	peptide binding	84/4208	249/18639	0.337349397590361	1.49426221998259	3.35848688734612e-05	0.000594931962901313
GO:0140662	ATP-dependent protein folding chaperone	21/4208	40/18639	0.525	2.32544557984791	3.51694381460119e-05	0.000615014277322566
GO:0031267	small GTPase binding	93/4208	283/18639	0.328621908127208	1.45560450227734	4.14752497940329e-05	0.000711129733791554
GO:0016887	ATP hydrolysis activity	129/4208	417/18639	0.309352517985612	1.37025227726564	4.17084887854284e-05	0.000711129733791554
GO:0003727	single-stranded RNA binding	37/4208	89/18639	0.415730337078652	1.84144433289187	4.71604497973529e-05	0.000794158685476412
GO:0008234	cysteine-type peptidase activity	66/4208	187/18639	0.352941176470588	1.56332475956162	4.8177372152953e-05	0.000801389458739364
GO:0030295	protein kinase activator activity	52/4208	139/18639	0.37410071942446	1.65704926553054	5.23777056073117e-05	0.000860761330703291
GO:0061733	protein-lysine-acetyltransferase activity	23/4208	47/18639	0.48936170212766	2.16758858506593	6.44171069344496e-05	0.00103890153657281
GO:0005126	cytokine receptor binding	90/4208	275/18639	0.327272727272727	1.44962841341168	6.47409315312968e-05	0.00103890153657281
GO:0032813	tumor necrosis factor receptor superfamily binding	24/4208	50/18639	0.48	2.1261216730038	6.6690824737794e-05	0.00105774749932966
GO:0005516	calmodulin binding	71/4208	207/18639	0.342995169082126	1.51926971400231	7.28988458614516e-05	0.0011429198362646
GO:0015101	organic cation transmembrane transporter activity	34/4208	81/18639	0.419753086419753	1.85926277989016	7.47194322704095e-05	0.00115815120019135
GO:0051082	unfolded protein binding	46/4208	121/18639	0.380165289256198	1.68391179335701	8.81659418075261e-05	0.00135121735534231
GO:0008017	microtubule binding	89/4208	276/18639	0.322463768115942	1.42832751281203	0.000127734666232245	0.00193588983045313
GO:0004896	cytokine receptor activity	38/4208	96/18639	0.395833333333333	1.75331214353612	0.000131841440496791	0.00197617280041343
GO:0001222	transcription corepressor binding	23/4208	49/18639	0.469387755102041	2.07911558159385	0.000144574574827151	0.0021434752180895
GO:0032395	MHC class II receptor activity	8/4208	10/18639	0.8	3.543536121673	0.000193329599904658	0.00280533589648887
GO:1905394	retromer complex binding	8/4208	10/18639	0.8	3.543536121673	0.000193329599904658	0.00280533589648887
GO:0001671	ATPase activator activity	15/4208	27/18639	0.555555555555556	2.46078897338403	0.000203923380003961	0.00292791042447793
GO:0051721	protein phosphatase 2A binding	16/4208	30/18639	0.533333333333333	2.36235741444867	0.000236848718208828	0.00336522553788377
GO:0003925	G protein activity	24/4208	54/18639	0.444444444444444	1.96863117870722	0.000295848039258364	0.00416017242833411
GO:0004402	histone acetyltransferase activity	20/4208	42/18639	0.476190476190476	2.10924769147203	0.000304607619463281	0.00423964074436648
GO:0051959	dynein light intermediate chain binding	15/4208	28/18639	0.535714285714286	2.37290365290603	0.000347824844213133	0.00479225340915872
GO:1901981	phosphatidylinositol phosphate binding	62/4208	185/18639	0.335135135135135	1.48445432124139	0.000410556078683204	0.00559998491323891
GO:0032396	inhibitory MHC class I receptor activity	9/4208	13/18639	0.692307692307692	3.06652164375548	0.000438711003772833	0.00592477038758559
GO:0019003	GDP binding	30/4208	75/18639	0.4	1.7717680608365	0.000523888642624828	0.00700572655431633
GO:0043522	leucine zipper domain binding	8/4208	11/18639	0.727272727272727	3.22139647424819	0.000567722532490857	0.00751818965356824
GO:0034212	protein N-acetyltransferase activity	23/4208	53/18639	0.433962264150943	1.92220119807734	0.000595828389251421	0.00781451848979748
GO:0010485	histone H4 acetyltransferase activity	17/4208	35/18639	0.485714285714286	2.15143264530147	0.000640299192900981	0.00823932168978243
GO:0061631	ubiquitin conjugating enzyme activity	17/4208	35/18639	0.485714285714286	2.15143264530147	0.000640299192900981	0.00823932168978243
GO:0019783	ubiquitin-like protein peptidase activity	45/4208	127/18639	0.354330708661417	1.56947958144966	0.000649288816103573	0.00827691537537639
GO:0140597	protein carrier chaperone	62/4208	188/18639	0.329787234042553	1.46076622037052	0.000659614406743301	0.00833068565553577
GO:0003714	transcription corepressor activity	66/4208	204/18639	0.323529411764706	1.43304769626482	0.00080474581134576	0.0100703971254644
GO:0015293	symporter activity	50/4208	146/18639	0.342465753424658	1.51692470962029	0.000822667095646967	0.0101543296393371
GO:0140713	histone chaperone activity	55/4208	164/18639	0.335365853658537	1.48547627051841	0.00082634207475544	0.0101543296393371
GO:0140693	molecular condensate scaffold activity	21/4208	48/18639	0.4375	1.93787131653992	0.000894304737162586	0.0108913541204443
GO:0032452	histone demethylase activity	15/4208	30/18639	0.5	2.21471007604563	0.000904724630626405	0.0109207468688001
GO:0101005	deubiquitinase activity	41/4208	115/18639	0.356521739130435	1.57918457596297	0.000958736251921785	0.0114711951545729
GO:0005161	platelet-derived growth factor receptor binding	9/4208	14/18639	0.642857142857143	2.84748438348724	0.000981870849403046	0.0116458420746587
GO:0004857	enzyme inhibitor activity	121/4208	416/18639	0.290865384615385	1.28836499616116	0.001062987396317	0.0124992655911757
GO:0019787	ubiquitin-like protein transferase activity	137/4208	479/18639	0.286012526096033	1.2668696468403	0.00108795274580197	0.0126834832929392
GO:0033691	sialic acid binding	12/4208	22/18639	0.545454545454545	2.41604735568614	0.00110994599445578	0.0126933524055828
GO:1990841	promoter-specific chromatin binding	27/4208	68/18639	0.397058823529412	1.75874035450682	0.00111327707302052	0.0126933524055828
GO:0004386	helicase activity	52/4208	155/18639	0.335483870967742	1.4859990187661	0.0011167172204325	0.0126933524055828
GO:0004842	ubiquitin-protein transferase activity	129/4208	449/18639	0.287305122494432	1.27259509937588	0.00124264864402636	0.0140080392599335
GO:0141052	histone H3 demethylase activity	14/4208	28/18639	0.5	2.21471007604563	0.00133722461100752	0.0149264258132802
GO:0030331	nuclear estrogen receptor binding	18/4208	40/18639	0.45	1.99323906844106	0.00138143554156763	0.0149264258132802
GO:0032451	demethylase activity	18/4208	40/18639	0.45	1.99323906844106	0.00138143554156763	0.0149264258132802
GO:0071949	FAD binding	18/4208	40/18639	0.45	1.99323906844106	0.00138143554156763	0.0149264258132802
GO:0005164	tumor necrosis factor receptor binding	15/4208	31/18639	0.483870967741935	2.14326781552803	0.00138977718349456	0.0149264258132802
GO:0140457	protein demethylase activity	15/4208	31/18639	0.483870967741935	2.14326781552803	0.00138977718349456	0.0149264258132802
GO:0016004	phospholipase activator activity	11/4208	20/18639	0.55	2.43618108365019	0.00163896487157901	0.0174652194127638
GO:1901682	sulfur compound transmembrane transporter activity	25/4208	63/18639	0.396825396825397	1.75770640956002	0.00168936512507915	0.0177884702441995
GO:0043539	protein serine/threonine kinase activator activity	28/4208	73/18639	0.383561643835616	1.69895567477473	0.00169538206139731	0.0177884702441995
GO:0005158	insulin receptor binding	12/4208	23/18639	0.521739130434783	2.31100181848239	0.00184671019517249	0.0191510741734685
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	7/4208	10/18639	0.7	3.10059410646388	0.00185354524883308	0.0191510741734685
GO:0017124	SH3 domain binding	40/4208	115/18639	0.347826086956522	1.54066787898826	0.00187112649443294	0.0191510741734685
GO:0140030	modification-dependent protein binding	56/4208	173/18639	0.323699421965318	1.43380074287347	0.0018875282914113	0.0191510741734685
GO:0004843	cysteine-type deubiquitinase activity	38/4208	108/18639	0.351851851851852	1.55849968314322	0.00189545088960282	0.0191510741734685
GO:0061578	K63-linked deubiquitinase activity	9/4208	15/18639	0.6	2.65765209125475	0.00196351501103938	0.0196929005518949
GO:0070412	R-SMAD binding	13/4208	26/18639	0.5	2.21471007604563	0.00198058996591906	0.0197191584928
GO:0051117	ATPase binding	31/4208	84/18639	0.369047619047619	1.63466696089082	0.00203998706491706	0.0201417335147887
GO:0010484	histone H3 acetyltransferase activity	14/4208	29/18639	0.482758620689655	2.13834076307854	0.00205256668515809	0.0201417335147887
GO:0030544	Hsp70 protein binding	21/4208	51/18639	0.411764705882353	1.82387888615522	0.00225940155213583	0.0220130265508091
GO:0005319	lipid transporter activity	57/4208	178/18639	0.320224719101124	1.41840982398428	0.00227584825882251	0.022016007269744
GO:0042826	histone deacetylase binding	43/4208	127/18639	0.338582677165354	1.49972493338523	0.00234608973096545	0.0225088568401535
GO:0016755	aminoacyltransferase activity	139/4208	496/18639	0.280241935483871	1.24130927649332	0.00235979950743544	0.0225088568401535
GO:0004706	JUN kinase kinase kinase activity	10/4208	18/18639	0.555555555555556	2.46078897338403	0.00242432465956263	0.0228053712802995
GO:0032393	MHC class I receptor activity	10/4208	18/18639	0.555555555555556	2.46078897338403	0.00242432465956263	0.0228053712802995
GO:0022804	active transmembrane transporter activity	129/4208	457/18639	0.282275711159737	1.25031772345683	0.00250809078262331	0.0234317522431383
GO:0061980	regulatory RNA binding	23/4208	58/18639	0.396551724137931	1.75649419824308	0.00256984597161964	0.0238453735053686
GO:0042393	histone binding	75/4208	247/18639	0.303643724696356	1.34496563322609	0.00266223224624925	0.0245133515590104
GO:0019208	phosphatase regulator activity	40/4208	117/18639	0.341880341880342	1.51433167592863	0.00267777813951067	0.0245133515590104
GO:0051879	Hsp90 protein binding	18/4208	42/18639	0.428571428571429	1.89832292232482	0.00269896572046969	0.0245425949514711
GO:0031490	chromatin DNA binding	43/4208	128/18639	0.3359375	1.48800833234316	0.0027741324110289	0.025059050388367
GO:0031994	insulin-like growth factor I binding	8/4208	13/18639	0.615384615384615	2.72579701667154	0.00284749559537006	0.0252206752732777
GO:0043560	insulin receptor substrate binding	8/4208	13/18639	0.615384615384615	2.72579701667154	0.00284749559537006	0.0252206752732777
GO:0140666	annealing activity	8/4208	13/18639	0.615384615384615	2.72579701667154	0.00284749559537006	0.0252206752732777
GO:0061659	ubiquitin-like protein ligase activity	107/4208	372/18639	0.287634408602151	1.27405364589722	0.00294751537208942	0.025738583028637
GO:0071889	14-3-3 protein binding	15/4208	33/18639	0.454545454545455	2.01337279640512	0.00301860675284001	0.025738583028637
GO:0004683	calcium/calmodulin-dependent protein kinase activity	13/4208	27/18639	0.481481481481481	2.13268377693283	0.00303736483006289	0.025738583028637
GO:0019888	protein phosphatase regulator activity	37/4208	107/18639	0.345794392523364	1.53166865072314	0.00303776565939873	0.025738583028637
GO:0015215	nucleotide transmembrane transporter activity	14/4208	30/18639	0.466666666666667	2.06706273764259	0.00305692848287331	0.025738583028637
GO:0043995	histone H4K5 acetyltransferase activity	14/4208	30/18639	0.466666666666667	2.06706273764259	0.00305692848287331	0.025738583028637
GO:0043996	histone H4K8 acetyltransferase activity	14/4208	30/18639	0.466666666666667	2.06706273764259	0.00305692848287331	0.025738583028637
GO:0043997	histone H4K12 acetyltransferase activity	14/4208	30/18639	0.466666666666667	2.06706273764259	0.00305692848287331	0.025738583028637
GO:0002039	p53 binding	26/4208	69/18639	0.376811594202899	1.66905686890395	0.00324784021976714	0.0270125247546486
GO:0008080	N-acetyltransferase activity	26/4208	69/18639	0.376811594202899	1.66905686890395	0.00324784021976714	0.0270125247546486
GO:0043021	ribonucleoprotein complex binding	56/4208	177/18639	0.31638418079096	1.40139846619836	0.00331668656718243	0.0274179422887081
GO:0019955	cytokine binding	47/4208	144/18639	0.326388888888889	1.44571352186312	0.00347670564776562	0.0285676295394717
GO:0022858	alanine transmembrane transporter activity	9/4208	16/18639	0.5625	2.49154883555133	0.00359277415035318	0.0288267290651867
GO:0030275	LRR domain binding	9/4208	16/18639	0.5625	2.49154883555133	0.00359277415035318	0.0288267290651867
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	9/4208	16/18639	0.5625	2.49154883555133	0.00359277415035318	0.0288267290651867
GO:0140328	floppase activity	9/4208	16/18639	0.5625	2.49154883555133	0.00359277415035318	0.0288267290651867
GO:0140674	ATP-dependent histone chaperone activity	49/4208	152/18639	0.322368421052632	1.42790518060836	0.00381849966849474	0.0304586757182855
GO:0004532	RNA exonuclease activity	17/4208	40/18639	0.425	1.88250356463878	0.00389794015822194	0.0305562665276709
GO:0061791	GTPase motor activity	17/4208	40/18639	0.425	1.88250356463878	0.00389794015822194	0.0305562665276709
GO:1990606	membrane scission GTPase motor activity	17/4208	40/18639	0.425	1.88250356463878	0.00389794015822194	0.0305562665276709
GO:1901505	carbohydrate derivative transmembrane transporter activity	21/4208	53/18639	0.39622641509434	1.75505326780974	0.00392059536543861	0.0305582404483329
GO:0005346	purine ribonucleotide transmembrane transporter activity	10/4208	19/18639	0.526315789473684	2.33127376425856	0.00408951849821246	0.0311132275060453
GO:0005520	insulin-like growth factor binding	10/4208	19/18639	0.526315789473684	2.33127376425856	0.00408951849821246	0.0311132275060453
GO:0003953	NAD+ nucleosidase activity	7/4208	11/18639	0.636363636363636	2.81872191496716	0.00410373500243197	0.0311132275060453
GO:0015173	aromatic amino acid transmembrane transporter activity	7/4208	11/18639	0.636363636363636	2.81872191496716	0.00410373500243197	0.0311132275060453
GO:0043394	proteoglycan binding	16/4208	37/18639	0.432432432432432	1.91542493063406	0.0041058511371614	0.0311132275060453
GO:0098531	ligand-modulated transcription factor activity	23/4208	60/18639	0.383333333333333	1.69794439163498	0.00425828207306142	0.0320900372798662
GO:0090482	vitamin transmembrane transporter activity	15/4208	34/18639	0.441176470588235	1.95415594945202	0.00428819782184771	0.0321379221373641
GO:0061775	cohesin loader activity	49/4208	153/18639	0.320261437908497	1.41857246700962	0.00440891013790787	0.0325542754100094
GO:0072349	modified amino acid transmembrane transporter activity	14/4208	31/18639	0.451612903225806	2.00038329449282	0.00442987661177345	0.0325542754100094
GO:0061630	ubiquitin protein ligase activity	101/4208	353/18639	0.286118980169972	1.26734117666067	0.00448686407297842	0.0325542754100094
GO:0004709	MAP kinase kinase kinase activity	12/4208	25/18639	0.48	2.1261216730038	0.00450475682490864	0.0325542754100094
GO:0120020	cholesterol transfer activity	12/4208	25/18639	0.48	2.1261216730038	0.00450475682490864	0.0325542754100094
GO:0036408	histone H3K14 acetyltransferase activity	13/4208	28/18639	0.464285714285714	2.05651649918523	0.00451081968657755	0.0325542754100094
GO:0051019	mitogen-activated protein kinase binding	13/4208	28/18639	0.464285714285714	2.05651649918523	0.00451081968657755	0.0325542754100094
GO:0043495	protein-membrane adaptor activity	19/4208	47/18639	0.404255319148936	1.79061665722838	0.00458008690435028	0.0328802028291252
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	69/4208	229/18639	0.301310043668122	1.33462877945108	0.00469329783899847	0.0335165353528477
GO:0001046	core promoter sequence-specific DNA binding	18/4208	44/18639	0.409090909090909	1.8120355167646	0.00492709471805905	0.0350029020595445
GO:0140658	ATP-dependent chromatin remodeler activity	50/4208	158/18639	0.316455696202532	1.40171523800356	0.00526999828328114	0.0365496590841719
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	17/4208	41/18639	0.414634146341463	1.83658884355003	0.00527879973576383	0.0365496590841719
GO:0015175	neutral L-amino acid transmembrane transporter activity	17/4208	41/18639	0.414634146341463	1.83658884355003	0.00527879973576383	0.0365496590841719
GO:0061650	ubiquitin-like protein conjugating enzyme activity	17/4208	41/18639	0.414634146341463	1.83658884355003	0.00527879973576383	0.0365496590841719
GO:0140828	metal cation:monoatomic cation antiporter activity	17/4208	41/18639	0.414634146341463	1.83658884355003	0.00527879973576383	0.0365496590841719
GO:0032454	histone H3K9 demethylase activity	8/4208	14/18639	0.571428571428571	2.53109722976643	0.0053349952566594	0.0365675051762986
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	8/4208	14/18639	0.571428571428571	2.53109722976643	0.0053349952566594	0.0365675051762986
GO:0015085	calcium ion transmembrane transporter activity	47/4208	147/18639	0.319727891156463	1.41620916427407	0.00539631777360364	0.0368028872159768
GO:0000510	H3-H4 histone complex chaperone activity	48/4208	151/18639	0.317880794701987	1.40802759801576	0.005613716502054	0.0372585896814808
GO:0140584	chromatin extrusion motor activity	48/4208	151/18639	0.317880794701987	1.40802759801576	0.005613716502054	0.0372585896814808
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	48/4208	151/18639	0.317880794701987	1.40802759801576	0.005613716502054	0.0372585896814808
GO:0140849	ATP-dependent H2AZ histone chaperone activity	48/4208	151/18639	0.317880794701987	1.40802759801576	0.005613716502054	0.0372585896814808
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	16/4208	38/18639	0.421052631578947	1.86501901140684	0.00562703040644065	0.0372585896814808
GO:0043531	ADP binding	16/4208	38/18639	0.421052631578947	1.86501901140684	0.00562703040644065	0.0372585896814808
GO:0051219	phosphoprotein binding	32/4208	93/18639	0.344086021505376	1.52410155770882	0.00606338473992545	0.039773821499753
GO:0005092	GDP-dissociation inhibitor activity	9/4208	17/18639	0.529411764705882	2.34498713934243	0.00611658168141286	0.039773821499753
GO:0051787	misfolded protein binding	9/4208	17/18639	0.529411764705882	2.34498713934243	0.00611658168141286	0.039773821499753
GO:0120013	lipid transfer activity	24/4208	65/18639	0.369230769230769	1.63547821000293	0.00615888653383603	0.039773821499753
GO:0070717	poly-purine tract binding	14/4208	32/18639	0.4375	1.93787131653992	0.00626146608412995	0.039773821499753
GO:0071813	lipoprotein particle binding	14/4208	32/18639	0.4375	1.93787131653992	0.00626146608412995	0.039773821499753
GO:0071814	protein-lipid complex binding	14/4208	32/18639	0.4375	1.93787131653992	0.00626146608412995	0.039773821499753
GO:0120015	sterol transfer activity	14/4208	32/18639	0.4375	1.93787131653992	0.00626146608412995	0.039773821499753
GO:0008186	ATP-dependent activity, acting on RNA	28/4208	79/18639	0.354430379746835	1.56992106656399	0.00626933403405197	0.039773821499753
GO:0015616	DNA translocase activity	48/4208	152/18639	0.315789473684211	1.39876425855513	0.00644227811754288	0.0405484471740445
GO:0140313	molecular sequestering activity	21/4208	55/18639	0.381818181818182	1.6912331489803	0.0064899075948233	0.0405484471740445
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	13/4208	29/18639	0.448275862068966	1.98560213714436	0.00650815025023089	0.0405484471740445
GO:0042288	MHC class I protein binding	10/4208	20/18639	0.5	2.21471007604563	0.00654007212484589	0.0405484471740445
GO:0043024	ribosomal small subunit binding	10/4208	20/18639	0.5	2.21471007604563	0.00654007212484589	0.0405484471740445
GO:0005112	Notch binding	12/4208	26/18639	0.461538461538462	2.04434776250366	0.00666832841832829	0.0407890408306336
GO:0050681	nuclear androgen receptor binding	12/4208	26/18639	0.461538461538462	2.04434776250366	0.00666832841832829	0.0407890408306336
GO:0005096	GTPase activator activity	79/4208	271/18639	0.291512915129151	1.29123318086793	0.00668906021275028	0.0407890408306336
GO:0000295	adenine nucleotide transmembrane transporter activity	11/4208	23/18639	0.478260869565217	2.11841833360886	0.00669849350884305	0.0407890408306336
GO:0015179	L-amino acid transmembrane transporter activity	23/4208	62/18639	0.370967741935484	1.64317199190482	0.006782961288081	0.0411198186530777
GO:0008135	translation factor activity, RNA binding	29/4208	83/18639	0.349397590361446	1.54762872783911	0.00686457824146585	0.041430463368847
GO:0035198	miRNA binding	17/4208	42/18639	0.404761904761905	1.79286053775122	0.00703308686616381	0.0422604867200327
GO:0016410	N-acyltransferase activity	32/4208	94/18639	0.340425531914894	1.50788771135021	0.00724130050895172	0.0433207626939042
GO:0004879	nuclear receptor activity	22/4208	59/18639	0.372881355932203	1.65164819230521	0.00746693781411237	0.0442639005533012
GO:0031593	polyubiquitin modification-dependent protein binding	22/4208	59/18639	0.372881355932203	1.65164819230521	0.00746693781411237	0.0442639005533012
GO:0015294	solute:monoatomic cation symporter activity	38/4208	116/18639	0.327586206896552	1.45101694637472	0.00749630573886553	0.0442639005533012
GO:0005095	GTPase inhibitor activity	7/4208	12/18639	0.583333333333333	2.58382842205323	0.00793773074354087	0.0462695074110673
GO:0015269	calcium-activated potassium channel activity	7/4208	12/18639	0.583333333333333	2.58382842205323	0.00793773074354087	0.0462695074110673
GO:0015368	calcium:monoatomic cation antiporter activity	7/4208	12/18639	0.583333333333333	2.58382842205323	0.00793773074354087	0.0462695074110673
GO:0008514	organic anion transmembrane transporter activity	78/4208	269/18639	0.28996282527881	1.28436718164728	0.00806662958504558	0.0468047899209038
GO:0015297	antiporter activity	43/4208	135/18639	0.318518518518519	1.41085234474018	0.0080981894584555	0.0468047899209038
GO:0180051	translation factor activity	29/4208	84/18639	0.345238095238095	1.52920457631722	0.00826702533800418	0.0475789981478384
GO:0070851	growth factor receptor binding	44/4208	139/18639	0.316546762589928	1.40211860929507	0.00841110652996476	0.048121923342059
GO:0003724	RNA helicase activity	27/4208	77/18639	0.350649350649351	1.55317330008395	0.00843192058559538	0.048121923342059
GO:0140311	protein sequestering activity	14/4208	33/18639	0.424242424242424	1.87914794331144	0.00865094138086989	0.0491661835146106
GO:0140296	general transcription initiation factor binding	20/4208	53/18639	0.377358490566038	1.67147930267595	0.00903280795781894	0.0509454861502844
GO:0003697	single-stranded DNA binding	39/4208	121/18639	0.322314049586777	1.42766434654181	0.00914501148944469	0.0509454861502844
GO:0001968	fibronectin binding	13/4208	30/18639	0.433333333333333	1.91941539923954	0.00914731983703369	0.0509454861502844
GO:0008187	poly-pyrimidine tract binding	13/4208	30/18639	0.433333333333333	1.91941539923954	0.00914731983703369	0.0509454861502844
GO:0000774	adenyl-nucleotide exchange factor activity	8/4208	15/18639	0.533333333333333	2.36235741444867	0.009188115537368	0.0509454861502844
GO:0120283	protein serine/threonine kinase binding	8/4208	15/18639	0.533333333333333	2.36235741444867	0.009188115537368	0.0509454861502844
GO:0004712	protein serine/threonine/tyrosine kinase activity	17/4208	43/18639	0.395348837209302	1.75116610664073	0.00922830225827168	0.0509611509323181
GO:0044325	transmembrane transporter binding	43/4208	136/18639	0.316176470588235	1.40047843044062	0.00930917028640818	0.051200436575245
GO:0046873	metal ion transmembrane transporter activity	123/4208	450/18639	0.273333333333333	1.21070817490494	0.00953084648964929	0.0522091349874764
GO:0004713	protein tyrosine kinase activity	44/4208	140/18639	0.314285714285714	1.39210347637154	0.00964098326017188	0.0526012046674978
GO:0030552	cAMP binding	11/4208	24/18639	0.458333333333333	2.03015090304183	0.00987829128246202	0.05325687474023
GO:0048027	mRNA 5'-UTR binding	11/4208	24/18639	0.458333333333333	2.03015090304183	0.00987829128246202	0.05325687474023
GO:0060229	lipase activator activity	11/4208	24/18639	0.458333333333333	2.03015090304183	0.00987829128246202	0.05325687474023
GO:0016407	acetyltransferase activity	32/4208	96/18639	0.333333333333333	1.47647338403042	0.010169228576913	0.0546095581846824
GO:0001784	phosphotyrosine residue binding	18/4208	47/18639	0.382978723404255	1.69637367526899	0.0108904483489248	0.0582532217566015
GO:0003689	DNA clamp loader activity	49/4208	160/18639	0.30625	1.35650992157795	0.0111394034185354	0.0593521338393839
GO:0008094	ATP-dependent activity, acting on DNA	62/4208	210/18639	0.295238095238095	1.30773356871266	0.0112536421048894	0.0597275012882067
GO:0140104	molecular carrier activity	72/4208	249/18639	0.289156626506024	1.28079618855651	0.0113048329028065	0.0597666359667757
GO:0005548	phospholipid transporter activity	24/4208	68/18639	0.352941176470588	1.56332475956162	0.0114973863938688	0.0605499422441584
GO:0005381	iron ion transmembrane transporter activity	6/4208	10/18639	0.6	2.65765209125475	0.0118294578903832	0.0613512568915693
GO:0030957	Tat protein binding	6/4208	10/18639	0.6	2.65765209125475	0.0118294578903832	0.0613512568915693
GO:0031996	thioesterase binding	6/4208	10/18639	0.6	2.65765209125475	0.0118294578903832	0.0613512568915693
GO:0035256	G protein-coupled glutamate receptor binding	6/4208	10/18639	0.6	2.65765209125475	0.0118294578903832	0.0613512568915693
GO:0043014	alpha-tubulin binding	17/4208	44/18639	0.386363636363636	1.71136687694435	0.011936469968776	0.0616717615053425
GO:0042169	SH2 domain binding	16/4208	41/18639	0.390243902439024	1.72855420569415	0.0130617749388123	0.0672311736473207
GO:0046966	nuclear thyroid hormone receptor binding	12/4208	28/18639	0.428571428571429	1.89832292232482	0.0133698089907129	0.0685579679072646
GO:0004535	poly(A)-specific ribonuclease activity	7/4208	13/18639	0.538461538461538	2.3850723895876	0.0138763384164068	0.0706243492536526
GO:0005035	death receptor activity	7/4208	13/18639	0.538461538461538	2.3850723895876	0.0138763384164068	0.0706243492536526
GO:0042974	nuclear retinoic acid receptor binding	11/4208	25/18639	0.44	1.94894486692015	0.0141003540705396	0.0712328998230224
GO:0047617	fatty acyl-CoA hydrolase activity	11/4208	25/18639	0.44	1.94894486692015	0.0141003540705396	0.0712328998230224
GO:0070034	telomerase RNA binding	10/4208	22/18639	0.454545454545455	2.01337279640512	0.0146685051044059	0.073829671448006
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	8/4208	16/18639	0.5	2.21471007604563	0.0147834569243828	0.074134688400214
GO:0046915	transition metal ion transmembrane transporter activity	17/4208	45/18639	0.377777777777778	1.67333650190114	0.0152330007160823	0.0761092050429899
GO:0030246	carbohydrate binding	79/4208	280/18639	0.282142857142857	1.24972925719718	0.0154532019526349	0.0769276184795403
GO:0000175	3'-5'-RNA exonuclease activity	14/4208	35/18639	0.4	1.7717680608365	0.0155347121142141	0.077052172086502
GO:0030159	signaling receptor complex adaptor activity	19/4208	52/18639	0.365384615384615	1.61844197864873	0.0156634386667368	0.0770822449248458
GO:0001786	phosphatidylserine binding	21/4208	59/18639	0.355932203389831	1.57657327447316	0.0157103109157677	0.0770822449248458
GO:0045309	protein phosphorylated amino acid binding	21/4208	59/18639	0.355932203389831	1.57657327447316	0.0157103109157677	0.0770822449248458
GO:0048487	beta-tubulin binding	16/4208	42/18639	0.380952380952381	1.68739815317762	0.016771736829673	0.0819951578339567
GO:0051059	NF-kappaB binding	13/4208	32/18639	0.40625	1.79945193678707	0.0168600279068809	0.0821324216606627
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	129/4208	484/18639	0.266528925619835	1.18056859425573	0.0183934737495396	0.089283623467516
GO:0001098	basal transcription machinery binding	21/4208	60/18639	0.35	1.55029705323194	0.0191487810795704	0.0919680894103309
GO:0001099	basal RNA polymerase II transcription machinery binding	21/4208	60/18639	0.35	1.55029705323194	0.0191487810795704	0.0919680894103309
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	21/4208	60/18639	0.35	1.55029705323194	0.0191487810795704	0.0919680894103309
GO:0015216	purine nucleotide transmembrane transporter activity	11/4208	26/18639	0.423076923076923	1.87398544896168	0.0195505062154946	0.0932408757969745
GO:0016289	acyl-CoA hydrolase activity	11/4208	26/18639	0.423076923076923	1.87398544896168	0.0195505062154946	0.0932408757969745
GO:0044013	histone H2B acetyltransferase activity	10/4208	23/18639	0.434782608695652	1.92583484873533	0.0207992832548388	0.0985077165263894
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	10/4208	23/18639	0.434782608695652	1.92583484873533	0.0207992832548388	0.0985077165263894
GO:0000099	sulfur amino acid transmembrane transporter activity	6/4208	11/18639	0.545454545454545	2.41604735568614	0.0211003253559247	0.0985645335119223
GO:0005536	D-glucose binding	6/4208	11/18639	0.545454545454545	2.41604735568614	0.0211003253559247	0.0985645335119223
GO:0050786	RAGE receptor binding	6/4208	11/18639	0.545454545454545	2.41604735568614	0.0211003253559247	0.0985645335119223
GO:0140537	transcription regulator activator activity	6/4208	11/18639	0.545454545454545	2.41604735568614	0.0211003253559247	0.0985645335119223
GO:0015932	nucleobase-containing compound transmembrane transporter activity	20/4208	57/18639	0.350877192982456	1.5541825095057	0.0213050745827914	0.09918130283593
GO:0015605	organophosphate ester transmembrane transporter activity	18/4208	50/18639	0.36	1.59459125475285	0.0215137285815457	0.0998119924667629
GO:0030742	GTP-dependent protein binding	9/4208	20/18639	0.45	1.99323906844106	0.0218421716938691	0.100651088481208
GO:0052745	inositol phosphate phosphatase activity	9/4208	20/18639	0.45	1.99323906844106	0.0218421716938691	0.100651088481208
GO:0001216	DNA-binding transcription activator activity	130/4208	491/18639	0.264765784114053	1.17275889973903	0.0220654798789517	0.100897170999639
GO:0019210	kinase inhibitor activity	29/4208	90/18639	0.322222222222222	1.42725760456274	0.0223966338381032	0.100897170999639
GO:0005545	1-phosphatidylinositol binding	7/4208	14/18639	0.5	2.21471007604563	0.0224176815761542	0.100897170999639
GO:0019992	diacylglycerol binding	7/4208	14/18639	0.5	2.21471007604563	0.0224176815761542	0.100897170999639
GO:0044548	S100 protein binding	7/4208	14/18639	0.5	2.21471007604563	0.0224176815761542	0.100897170999639
GO:1901474	azole transmembrane transporter activity	7/4208	14/18639	0.5	2.21471007604563	0.0224176815761542	0.100897170999639
GO:0030169	low-density lipoprotein particle binding	8/4208	17/18639	0.470588235294118	2.08443301274883	0.022487346029245	0.100897170999639
GO:1990226	histone methyltransferase binding	8/4208	17/18639	0.470588235294118	2.08443301274883	0.022487346029245	0.100897170999639
GO:0015144	carbohydrate transmembrane transporter activity	15/4208	40/18639	0.375	1.66103255703422	0.0234969639728114	0.104738100846126
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	15/4208	40/18639	0.375	1.66103255703422	0.0234969639728114	0.104738100846126
GO:0030165	PDZ domain binding	27/4208	83/18639	0.325301204819277	1.44089571212607	0.0237937873217517	0.105715719566349
GO:0042626	ATPase-coupled transmembrane transporter activity	31/4208	98/18639	0.316326530612245	1.40114310933499	0.0242676817854668	0.107471162192782
GO:0061134	peptidase regulator activity	64/4208	226/18639	0.283185840707965	1.25434906961876	0.0250055938238133	0.110380679532949
GO:0000149	SNARE binding	33/4208	106/18639	0.311320754716981	1.37897042470765	0.0259362324214217	0.113925122658668
GO:0030551	cyclic nucleotide binding	14/4208	37/18639	0.378378378378378	1.6759968143048	0.0259755961487139	0.113925122658668
GO:0008266	poly(U) RNA binding	11/4208	27/18639	0.407407407407407	1.80457858048162	0.0264099734775004	0.11472701071461
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	11/4208	27/18639	0.407407407407407	1.80457858048162	0.0264099734775004	0.11472701071461
GO:0003743	translation initiation factor activity	18/4208	51/18639	0.352941176470588	1.56332475956162	0.0264107634636273	0.11472701071461
GO:0004860	protein kinase inhibitor activity	27/4208	84/18639	0.321428571428571	1.42374219174362	0.0277214562102029	0.120038305621323
GO:0001091	RNA polymerase II general transcription initiation factor binding	10/4208	24/18639	0.416666666666667	1.84559173003802	0.0285999918065366	0.120402434642333
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	10/4208	24/18639	0.416666666666667	1.84559173003802	0.0285999918065366	0.120402434642333
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	10/4208	24/18639	0.416666666666667	1.84559173003802	0.0285999918065366	0.120402434642333
GO:0015295	solute:proton symporter activity	10/4208	24/18639	0.416666666666667	1.84559173003802	0.0285999918065366	0.120402434642333
GO:0042625	ATPase-coupled ion transmembrane transporter activity	10/4208	24/18639	0.416666666666667	1.84559173003802	0.0285999918065366	0.120402434642333
GO:0043998	histone H2A acetyltransferase activity	10/4208	24/18639	0.416666666666667	1.84559173003802	0.0285999918065366	0.120402434642333
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	10/4208	24/18639	0.416666666666667	1.84559173003802	0.0285999918065366	0.120402434642333
GO:0046961	proton-transporting ATPase activity, rotational mechanism	10/4208	24/18639	0.416666666666667	1.84559173003802	0.0285999918065366	0.120402434642333
GO:0070300	phosphatidic acid binding	10/4208	24/18639	0.416666666666667	1.84559173003802	0.0285999918065366	0.120402434642333
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	13/4208	34/18639	0.382352941176471	1.69360182285842	0.0286904074628754	0.120411433167268
GO:0042287	MHC protein binding	15/4208	41/18639	0.365853658536585	1.62051956783826	0.02951726533858	0.123501686876758
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	9/4208	21/18639	0.428571428571429	1.89832292232482	0.0307305226707738	0.127019493705865
GO:0005123	death receptor binding	9/4208	21/18639	0.428571428571429	1.89832292232482	0.0307305226707738	0.127019493705865
GO:0051010	microtubule plus-end binding	9/4208	21/18639	0.428571428571429	1.89832292232482	0.0307305226707738	0.127019493705865
GO:0070182	DNA polymerase binding	9/4208	21/18639	0.428571428571429	1.89832292232482	0.0307305226707738	0.127019493705865
GO:0008525	phosphatidylcholine transporter activity	8/4208	18/18639	0.444444444444444	1.96863117870722	0.0326301518900306	0.133583744932162
GO:0034185	apolipoprotein binding	8/4208	18/18639	0.444444444444444	1.96863117870722	0.0326301518900306	0.133583744932162
GO:0070628	proteasome binding	8/4208	18/18639	0.444444444444444	1.96863117870722	0.0326301518900306	0.133583744932162
GO:0042887	amide transmembrane transporter activity	14/4208	38/18639	0.368421052631579	1.63189163498099	0.0328075491147648	0.133583744932162
GO:0140303	intramembrane lipid transporter activity	16/4208	45/18639	0.355555555555556	1.57490494296578	0.032808324451814	0.133583744932162
GO:0005402	carbohydrate:monoatomic cation symporter activity	7/4208	15/18639	0.466666666666667	2.06706273764259	0.0339935518600921	0.134681910192429
GO:0042809	nuclear vitamin D receptor binding	7/4208	15/18639	0.466666666666667	2.06706273764259	0.0339935518600921	0.134681910192429
GO:0050700	CARD domain binding	7/4208	15/18639	0.466666666666667	2.06706273764259	0.0339935518600921	0.134681910192429
GO:0005078	MAP-kinase scaffold activity	6/4208	12/18639	0.5	2.21471007604563	0.0342629199683085	0.134681910192429
GO:0035197	siRNA binding	6/4208	12/18639	0.5	2.21471007604563	0.0342629199683085	0.134681910192429
GO:0070008	serine-type exopeptidase activity	6/4208	12/18639	0.5	2.21471007604563	0.0342629199683085	0.134681910192429
GO:0097677	STAT family protein binding	6/4208	12/18639	0.5	2.21471007604563	0.0342629199683085	0.134681910192429
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	6/4208	12/18639	0.5	2.21471007604563	0.0342629199683085	0.134681910192429
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	6/4208	12/18639	0.5	2.21471007604563	0.0342629199683085	0.134681910192429
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	6/4208	12/18639	0.5	2.21471007604563	0.0342629199683085	0.134681910192429
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	6/4208	12/18639	0.5	2.21471007604563	0.0342629199683085	0.134681910192429
GO:1990247	N6-methyladenosine-containing RNA reader activity	6/4208	12/18639	0.5	2.21471007604563	0.0342629199683085	0.134681910192429
GO:0042578	phosphoric ester hydrolase activity	97/4208	363/18639	0.267217630853994	1.18361915909877	0.0343682196415095	0.134707619514422
GO:0051119	sugar transmembrane transporter activity	11/4208	28/18639	0.392857142857143	1.74012934546442	0.0348477269689513	0.135806570244713
GO:0097718	disordered domain specific binding	11/4208	28/18639	0.392857142857143	1.74012934546442	0.0348477269689513	0.135806570244713
GO:0005154	epidermal growth factor receptor binding	13/4208	35/18639	0.371428571428571	1.64521319934818	0.0364642274416299	0.141298881336316
GO:0043015	gamma-tubulin binding	13/4208	35/18639	0.371428571428571	1.64521319934818	0.0364642274416299	0.141298881336316
GO:0008307	structural constituent of muscle	15/4208	42/18639	0.357142857142857	1.58193576860402	0.036598114510195	0.141415943886419
GO:0050660	flavin adenine dinucleotide binding	27/4208	86/18639	0.313953488372093	1.3906319082147	0.0370459475071624	0.142742012428728
GO:0008139	nuclear localization sequence binding	10/4208	25/18639	0.4	1.7717680608365	0.0382664169638678	0.14624698772083
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	10/4208	25/18639	0.4	1.7717680608365	0.0382664169638678	0.14624698772083
GO:0033218	amide binding	68/4208	247/18639	0.275303643724696	1.21943550745832	0.0382772541175486	0.14624698772083
GO:0030291	protein serine/threonine kinase inhibitor activity	16/4208	46/18639	0.347826086956522	1.54066787898826	0.0400685822394016	0.152223785772901
GO:0022884	macromolecule transmembrane transporter activity	12/4208	32/18639	0.375	1.66103255703422	0.0405218981268919	0.152223785772901
GO:0016504	peptidase activator activity	19/4208	57/18639	0.333333333333333	1.47647338403042	0.0412172517488315	0.152223785772901
GO:0015171	amino acid transmembrane transporter activity	31/4208	102/18639	0.303921568627451	1.34619632073362	0.0412980017714382	0.152223785772901
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	9/4208	22/18639	0.409090909090909	1.8120355167646	0.0418503809859514	0.152223785772901
GO:0032931	histone H3K56 acetyltransferase activity	9/4208	22/18639	0.409090909090909	1.8120355167646	0.0418503809859514	0.152223785772901
GO:0043992	histone H3K9 acetyltransferase activity	9/4208	22/18639	0.409090909090909	1.8120355167646	0.0418503809859514	0.152223785772901
GO:0043993	histone H3K18 acetyltransferase activity	9/4208	22/18639	0.409090909090909	1.8120355167646	0.0418503809859514	0.152223785772901
GO:0043994	histone H3K23 acetyltransferase activity	9/4208	22/18639	0.409090909090909	1.8120355167646	0.0418503809859514	0.152223785772901
GO:0043999	histone H2AK5 acetyltransferase activity	9/4208	22/18639	0.409090909090909	1.8120355167646	0.0418503809859514	0.152223785772901
GO:0044012	histone H2AK9 acetyltransferase activity	9/4208	22/18639	0.409090909090909	1.8120355167646	0.0418503809859514	0.152223785772901
GO:0044014	histone H2BK5 acetyltransferase activity	9/4208	22/18639	0.409090909090909	1.8120355167646	0.0418503809859514	0.152223785772901
GO:0044015	histone H2BK12 acetyltransferase activity	9/4208	22/18639	0.409090909090909	1.8120355167646	0.0418503809859514	0.152223785772901
GO:0044016	histone H3K4 acetyltransferase activity	9/4208	22/18639	0.409090909090909	1.8120355167646	0.0418503809859514	0.152223785772901
GO:0044017	histone H3K27 acetyltransferase activity	9/4208	22/18639	0.409090909090909	1.8120355167646	0.0418503809859514	0.152223785772901
GO:0044018	histone H3K36 acetyltransferase activity	9/4208	22/18639	0.409090909090909	1.8120355167646	0.0418503809859514	0.152223785772901
GO:0046972	histone H4K16 acetyltransferase activity	9/4208	22/18639	0.409090909090909	1.8120355167646	0.0418503809859514	0.152223785772901
GO:0140908	histone H3K122 acetyltransferase activity	9/4208	22/18639	0.409090909090909	1.8120355167646	0.0418503809859514	0.152223785772901
GO:0005518	collagen binding	23/4208	72/18639	0.319444444444444	1.41495365969582	0.042731805818118	0.155016444510407
GO:0003774	cytoskeletal motor activity	44/4208	153/18639	0.287581699346405	1.27382017445762	0.043743809655219	0.158266727771137
GO:0140034	methylation-dependent protein binding	24/4208	76/18639	0.315789473684211	1.39876425855513	0.0443785238307659	0.16013837699779
GO:0048156	tau protein binding	15/4208	43/18639	0.348837209302326	1.545146564683	0.0448246471338392	0.16114958333913
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	11/4208	29/18639	0.379310344827586	1.68012488527599	0.0450131900676014	0.16114958333913
GO:0097472	cyclin-dependent protein kinase activity	11/4208	29/18639	0.379310344827586	1.68012488527599	0.0450131900676014	0.16114958333913
GO:1990380	K48-linked deubiquitinase activity	8/4208	19/18639	0.421052631578947	1.86501901140684	0.0454839155280102	0.162408536073837
GO:0038024	cargo receptor activity	21/4208	65/18639	0.323076923076923	1.43104343375256	0.0457218924698203	0.162832013913407
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	38/4208	130/18639	0.292307692307692	1.29475358291898	0.046064371497038	0.162955042930273
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	18/4208	54/18639	0.333333333333333	1.47647338403042	0.0461148435271888	0.162955042930273
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	18/4208	54/18639	0.333333333333333	1.47647338403042	0.0461148435271888	0.162955042930273
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	7/4208	16/18639	0.4375	1.93787131653992	0.0489347368100883	0.171349688340399
GO:0070411	I-SMAD binding	7/4208	16/18639	0.4375	1.93787131653992	0.0489347368100883	0.171349688340399
GO:0035401	histone H3Y41 kinase activity	34/4208	115/18639	0.295652173913043	1.30956769714002	0.0489929460797328	0.171349688340399
GO:0140801	histone H2AXY142 kinase activity	34/4208	115/18639	0.295652173913043	1.30956769714002	0.0489929460797328	0.171349688340399
GO:0004112	cyclic-nucleotide phosphodiesterase activity	10/4208	26/18639	0.384615384615385	1.70362313541971	0.0499638611816011	0.173411467307134
GO:0005227	calcium-activated cation channel activity	10/4208	26/18639	0.384615384615385	1.70362313541971	0.0499638611816011	0.173411467307134
GO:0008143	poly(A) binding	10/4208	26/18639	0.384615384615385	1.70362313541971	0.0499638611816011	0.173411467307134
GO:0015036	disulfide oxidoreductase activity	14/4208	40/18639	0.35	1.55029705323194	0.0501950052465193	0.173771541005717
GO:0019239	deaminase activity	12/4208	33/18639	0.363636363636364	1.61069823712409	0.0509938775429515	0.174245553184541
GO:0019956	chemokine binding	12/4208	33/18639	0.363636363636364	1.61069823712409	0.0509938775429515	0.174245553184541
GO:0140416	transcription regulator inhibitor activity	12/4208	33/18639	0.363636363636364	1.61069823712409	0.0509938775429515	0.174245553184541
GO:0005262	calcium channel activity	38/4208	131/18639	0.290076335877863	1.2848699677822	0.051191421243098	0.174245553184541
GO:0005048	signal sequence binding	17/4208	51/18639	0.333333333333333	1.47647338403042	0.0516460921079407	0.174245553184541
GO:0005172	vascular endothelial growth factor receptor binding	6/4208	13/18639	0.461538461538462	2.04434776250366	0.0517371327270816	0.174245553184541
GO:0008035	high-density lipoprotein particle binding	6/4208	13/18639	0.461538461538462	2.04434776250366	0.0517371327270816	0.174245553184541
GO:0031432	titin binding	6/4208	13/18639	0.461538461538462	2.04434776250366	0.0517371327270816	0.174245553184541
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	6/4208	13/18639	0.461538461538462	2.04434776250366	0.0517371327270816	0.174245553184541
GO:0140333	glycerophospholipid flippase activity	6/4208	13/18639	0.461538461538462	2.04434776250366	0.0517371327270816	0.174245553184541
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	6/4208	13/18639	0.461538461538462	2.04434776250366	0.0517371327270816	0.174245553184541
GO:0004955	prostaglandin receptor activity	5/4208	10/18639	0.5	2.21471007604563	0.0529208188267555	0.175203875921589
GO:0005031	tumor necrosis factor receptor activity	5/4208	10/18639	0.5	2.21471007604563	0.0529208188267555	0.175203875921589
GO:0008140	cAMP response element binding protein binding	5/4208	10/18639	0.5	2.21471007604563	0.0529208188267555	0.175203875921589
GO:0015658	branched-chain amino acid transmembrane transporter activity	5/4208	10/18639	0.5	2.21471007604563	0.0529208188267555	0.175203875921589
GO:0043121	neurotrophin binding	5/4208	10/18639	0.5	2.21471007604563	0.0529208188267555	0.175203875921589
GO:0051880	G-quadruplex DNA binding	5/4208	10/18639	0.5	2.21471007604563	0.0529208188267555	0.175203875921589
GO:0070513	death domain binding	5/4208	10/18639	0.5	2.21471007604563	0.0529208188267555	0.175203875921589
GO:0001223	transcription coactivator binding	15/4208	44/18639	0.340909090909091	1.51002959730384	0.0542722298977802	0.179242909396058
GO:0097110	scaffold protein binding	22/4208	70/18639	0.314285714285714	1.39210347637154	0.0552002332987036	0.181867435312637
GO:0005283	amino acid:sodium symporter activity	9/4208	23/18639	0.391304347826087	1.7332513638618	0.0553832295273811	0.182030662832163
GO:0042805	actinin binding	13/4208	37/18639	0.351351351351351	1.55628275614017	0.0562707067743346	0.184502990481232
GO:0035064	methylated histone binding	23/4208	74/18639	0.310810810810811	1.37671166889323	0.0569594697779578	0.185652881093163
GO:0035925	mRNA 3'-UTR AU-rich region binding	11/4208	30/18639	0.366666666666667	1.62412072243346	0.0570297340014922	0.185652881093163
GO:0070566	adenylyltransferase activity	11/4208	30/18639	0.366666666666667	1.62412072243346	0.0570297340014922	0.185652881093163
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	16/4208	48/18639	0.333333333333333	1.47647338403042	0.0579053011607784	0.188054359007861
GO:0061135	endopeptidase regulator activity	51/4208	184/18639	0.277173913043478	1.22771971606877	0.0586219366483591	0.18992950496048
GO:0042562	hormone binding	28/4208	94/18639	0.297872340425532	1.31940174743144	0.0634699111408018	0.205149191459843
GO:0140097	catalytic activity, acting on DNA	88/4208	336/18639	0.261904761904762	1.16008623030961	0.0643873397889921	0.207622533031171
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	19/4208	60/18639	0.316666666666667	1.4026497148289	0.0665759832462819	0.214173681952661
GO:0008484	sulfuric ester hydrolase activity	7/4208	17/18639	0.411764705882353	1.82387888615522	0.0674479103566785	0.214950817118013
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	7/4208	17/18639	0.411764705882353	1.82387888615522	0.0674479103566785	0.214950817118013
GO:0036041	long-chain fatty acid binding	7/4208	17/18639	0.411764705882353	1.82387888615522	0.0674479103566785	0.214950817118013
GO:0046965	nuclear retinoid X receptor binding	7/4208	17/18639	0.411764705882353	1.82387888615522	0.0674479103566785	0.214950817118013
GO:0001540	amyloid-beta binding	25/4208	83/18639	0.301204819277108	1.33416269641303	0.0680667199620344	0.216417263469032
GO:0016763	pentosyltransferase activity	16/4208	49/18639	0.326530612244898	1.44634127415225	0.0685991120473534	0.217602764726953
GO:0032934	sterol binding	21/4208	68/18639	0.308823529411765	1.36790916461642	0.0708682904315815	0.223536988133227
GO:0016411	acylglycerol O-acyltransferase activity	11/4208	31/18639	0.354838709677419	1.57172973138722	0.0709893044653998	0.223536988133227
GO:0070325	lipoprotein particle receptor binding	11/4208	31/18639	0.354838709677419	1.57172973138722	0.0709893044653998	0.223536988133227
GO:0019957	C-C chemokine binding	9/4208	24/18639	0.375	1.66103255703422	0.0714531721598878	0.223536988133227
GO:0035035	histone acetyltransferase binding	9/4208	24/18639	0.375	1.66103255703422	0.0714531721598878	0.223536988133227
GO:0050699	WW domain binding	9/4208	24/18639	0.375	1.66103255703422	0.0714531721598878	0.223536988133227
GO:0043175	RNA polymerase core enzyme binding	14/4208	42/18639	0.333333333333333	1.47647338403042	0.0730761372097455	0.228091192572295
GO:0005347	ATP transmembrane transporter activity	6/4208	14/18639	0.428571428571429	1.89832292232482	0.0737267210902771	0.228552835379859
GO:0008474	palmitoyl-(protein) hydrolase activity	6/4208	14/18639	0.428571428571429	1.89832292232482	0.0737267210902771	0.228552835379859
GO:0098599	palmitoyl hydrolase activity	6/4208	14/18639	0.428571428571429	1.89832292232482	0.0737267210902771	0.228552835379859
GO:1902936	phosphatidylinositol bisphosphate binding	32/4208	111/18639	0.288288288288288	1.27694995375604	0.0740397104910237	0.229002641972237
GO:0004527	exonuclease activity	25/4208	84/18639	0.297619047619048	1.31827980717002	0.0768776427025925	0.236285647290775
GO:0004180	carboxypeptidase activity	15/4208	46/18639	0.326086956521739	1.4443761365515	0.0770697957085189	0.236285647290775
GO:0030276	clathrin binding	15/4208	46/18639	0.326086956521739	1.4443761365515	0.0770697957085189	0.236285647290775
GO:0005343	organic acid:sodium symporter activity	12/4208	35/18639	0.342857142857143	1.51865833785986	0.0770873262788817	0.236285647290775
GO:0002162	dystroglycan binding	5/4208	11/18639	0.454545454545455	2.01337279640512	0.0794378967191146	0.237803343934573
GO:0004954	prostanoid receptor activity	5/4208	11/18639	0.454545454545455	2.01337279640512	0.0794378967191146	0.237803343934573
GO:0005225	volume-sensitive anion channel activity	5/4208	11/18639	0.454545454545455	2.01337279640512	0.0794378967191146	0.237803343934573
GO:0008432	JUN kinase binding	5/4208	11/18639	0.454545454545455	2.01337279640512	0.0794378967191146	0.237803343934573
GO:0008526	phosphatidylinositol transfer activity	5/4208	11/18639	0.454545454545455	2.01337279640512	0.0794378967191146	0.237803343934573
GO:0016176	superoxide-generating NADPH oxidase activator activity	5/4208	11/18639	0.454545454545455	2.01337279640512	0.0794378967191146	0.237803343934573
GO:0019215	intermediate filament binding	5/4208	11/18639	0.454545454545455	2.01337279640512	0.0794378967191146	0.237803343934573
GO:0034056	estrogen response element binding	5/4208	11/18639	0.454545454545455	2.01337279640512	0.0794378967191146	0.237803343934573
GO:0045294	alpha-catenin binding	5/4208	11/18639	0.454545454545455	2.01337279640512	0.0794378967191146	0.237803343934573
GO:0047676	arachidonate-CoA ligase activity	5/4208	11/18639	0.454545454545455	2.01337279640512	0.0794378967191146	0.237803343934573
GO:0046875	ephrin receptor binding	10/4208	28/18639	0.357142857142857	1.58193576860402	0.0799142905061067	0.237803343934573
GO:0009931	calcium-dependent protein serine/threonine kinase activity	8/4208	21/18639	0.380952380952381	1.68739815317762	0.0800232660307689	0.237803343934573
GO:0019200	carbohydrate kinase activity	8/4208	21/18639	0.380952380952381	1.68739815317762	0.0800232660307689	0.237803343934573
GO:0072542	protein phosphatase activator activity	8/4208	21/18639	0.380952380952381	1.68739815317762	0.0800232660307689	0.237803343934573
GO:0046943	carboxylic acid transmembrane transporter activity	51/4208	188/18639	0.271276595744681	1.2015980199822	0.0809409072713923	0.240007385909085
GO:0015081	sodium ion transmembrane transporter activity	45/4208	164/18639	0.274390243902439	1.2153896758787	0.0825611431714574	0.244280692594074
GO:0015485	cholesterol binding	17/4208	54/18639	0.314814814814815	1.39444708491762	0.0835437626053162	0.246653013406172
GO:0008375	acetylglucosaminyltransferase activity	14/4208	43/18639	0.325581395348837	1.44213679370413	0.086714787591217	0.255462138821642
GO:0005342	organic acid transmembrane transporter activity	51/4208	189/18639	0.26984126984127	1.19524035850081	0.0873437743450191	0.256760578031479
GO:0051213	dioxygenase activity	27/4208	93/18639	0.290322580645161	1.28596068931682	0.0881669062029067	0.25862292486186
GO:0015172	acidic amino acid transmembrane transporter activity	7/4208	18/18639	0.388888888888889	1.72255228136882	0.0896046657445455	0.260433611758969
GO:0030228	lipoprotein particle receptor activity	7/4208	18/18639	0.388888888888889	1.72255228136882	0.0896046657445455	0.260433611758969
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	7/4208	18/18639	0.388888888888889	1.72255228136882	0.0896046657445455	0.260433611758969
GO:0098641	cadherin binding involved in cell-cell adhesion	7/4208	18/18639	0.388888888888889	1.72255228136882	0.0896046657445455	0.260433611758969
GO:0004866	endopeptidase inhibitor activity	44/4208	161/18639	0.273291925465839	1.21052476206221	0.0898436027740715	0.260433611758969
GO:0015296	monoatomic anion:monoatomic cation symporter activity	9/4208	25/18639	0.36	1.59459125475285	0.0901207219576491	0.260433611758969
GO:0019211	phosphatase activator activity	9/4208	25/18639	0.36	1.59459125475285	0.0901207219576491	0.260433611758969
GO:1990782	protein tyrosine kinase binding	33/4208	117/18639	0.282051282051282	1.24932363264112	0.0907832296430345	0.26168870554482
GO:0004540	RNA nuclease activity	34/4208	121/18639	0.28099173553719	1.24463045595953	0.0909387437157221	0.26168870554482
GO:0000993	RNA polymerase II complex binding	12/4208	36/18639	0.333333333333333	1.47647338403042	0.0928177500599808	0.265973552692886
GO:0005484	SNAP receptor activity	12/4208	36/18639	0.333333333333333	1.47647338403042	0.0928177500599808	0.265973552692886
GO:0008374	O-acyltransferase activity	17/4208	55/18639	0.309090909090909	1.36909350155548	0.0965123162501339	0.275980711457406
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	25/4208	86/18639	0.290697674418605	1.28762213723583	0.0967441233254489	0.276064820535381
GO:0005416	amino acid:monoatomic cation symporter activity	10/4208	29/18639	0.344827586206897	1.52738625934181	0.0982832907368989	0.279288351177354
GO:0051861	glycolipid binding	10/4208	29/18639	0.344827586206897	1.52738625934181	0.0982832907368989	0.279288351177354
GO:0016791	phosphatase activity	71/4208	273/18639	0.26007326007326	1.15197373918857	0.0993504652822125	0.281733959760786
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	6/4208	15/18639	0.4	1.7717680608365	0.100215500577067	0.28184318100437
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	6/4208	15/18639	0.4	1.7717680608365	0.100215500577067	0.28184318100437
GO:0004953	icosanoid receptor activity	6/4208	15/18639	0.4	1.7717680608365	0.100215500577067	0.28184318100437
GO:0047372	monoacylglycerol lipase activity	6/4208	15/18639	0.4	1.7717680608365	0.100215500577067	0.28184318100437
GO:0015377	chloride:monoatomic cation symporter activity	8/4208	22/18639	0.363636363636364	1.61069823712409	0.101836343199236	0.284692089477219
GO:0140517	protein-RNA adaptor activity	8/4208	22/18639	0.363636363636364	1.61069823712409	0.101836343199236	0.284692089477219
GO:0016790	thiolester hydrolase activity	14/4208	44/18639	0.318181818181818	1.40936095748358	0.101854647848154	0.284692089477219
GO:0038187	pattern recognition receptor activity	15/4208	48/18639	0.3125	1.38419379752852	0.105319715230017	0.293775238392113
GO:0015370	solute:sodium symporter activity	23/4208	79/18639	0.291139240506329	1.28957801896328	0.106304544633803	0.295917140572465
GO:0008081	phosphoric diester hydrolase activity	25/4208	87/18639	0.28735632183908	1.27282188278484	0.107822945504259	0.299532581808166
GO:0005080	protein kinase C binding	16/4208	52/18639	0.307692307692308	1.36289850833577	0.108232028504166	0.300057900161955
GO:0005160	transforming growth factor beta receptor binding	9/4208	26/18639	0.346153846153846	1.53326082187774	0.111380236486145	0.301716090329449
GO:0008157	protein phosphatase 1 binding	9/4208	26/18639	0.346153846153846	1.53326082187774	0.111380236486145	0.301716090329449
GO:0015145	monosaccharide transmembrane transporter activity	9/4208	26/18639	0.346153846153846	1.53326082187774	0.111380236486145	0.301716090329449
GO:0043548	phosphatidylinositol 3-kinase binding	9/4208	26/18639	0.346153846153846	1.53326082187774	0.111380236486145	0.301716090329449
GO:0051139	metal cation:proton antiporter activity	9/4208	26/18639	0.346153846153846	1.53326082187774	0.111380236486145	0.301716090329449
GO:0052742	phosphatidylinositol kinase activity	9/4208	26/18639	0.346153846153846	1.53326082187774	0.111380236486145	0.301716090329449
GO:0097602	cullin family protein binding	9/4208	26/18639	0.346153846153846	1.53326082187774	0.111380236486145	0.301716090329449
GO:0004000	adenosine deaminase activity	5/4208	12/18639	0.416666666666667	1.84559173003802	0.111705737255404	0.301716090329449
GO:0016423	tRNA (guanine) methyltransferase activity	5/4208	12/18639	0.416666666666667	1.84559173003802	0.111705737255404	0.301716090329449
GO:0035251	UDP-glucosyltransferase activity	5/4208	12/18639	0.416666666666667	1.84559173003802	0.111705737255404	0.301716090329449
GO:0042301	phosphate ion binding	5/4208	12/18639	0.416666666666667	1.84559173003802	0.111705737255404	0.301716090329449
GO:0070410	co-SMAD binding	5/4208	12/18639	0.416666666666667	1.84559173003802	0.111705737255404	0.301716090329449
GO:1990817	poly(A) RNA polymerase activity	5/4208	12/18639	0.416666666666667	1.84559173003802	0.111705737255404	0.301716090329449
GO:0004518	nuclease activity	55/4208	209/18639	0.263157894736842	1.16563688212928	0.112961162141357	0.304504002294094
GO:0001727	lipid kinase activity	13/4208	41/18639	0.317073170731707	1.4044502921265	0.114823690721197	0.307879010432844
GO:0140318	protein transporter activity	13/4208	41/18639	0.317073170731707	1.4044502921265	0.114823690721197	0.307879010432844
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	7/4208	19/18639	0.368421052631579	1.63189163498099	0.115341770037524	0.307879010432844
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	7/4208	19/18639	0.368421052631579	1.63189163498099	0.115341770037524	0.307879010432844
GO:0022821	solute:potassium antiporter activity	7/4208	19/18639	0.368421052631579	1.63189163498099	0.115341770037524	0.307879010432844
GO:0016779	nucleotidyltransferase activity	37/4208	136/18639	0.272058823529412	1.20506283549541	0.117696264045224	0.31355020343298
GO:0004715	non-membrane spanning protein tyrosine kinase activity	14/4208	45/18639	0.311111111111111	1.37804182509506	0.118496793434718	0.313720182318524
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	35/4208	128/18639	0.2734375	1.21116957283745	0.118617734393582	0.313720182318524
GO:0001965	G-protein alpha-subunit binding	10/4208	30/18639	0.333333333333333	1.47647338403042	0.118910069104602	0.313720182318524
GO:0022839	monoatomic ion-gated channel activity	10/4208	30/18639	0.333333333333333	1.47647338403042	0.118910069104602	0.313720182318524
GO:0031624	ubiquitin conjugating enzyme binding	10/4208	30/18639	0.333333333333333	1.47647338403042	0.118910069104602	0.313720182318524
GO:0043022	ribosome binding	31/4208	112/18639	0.276785714285714	1.22600022066812	0.119911239253576	0.315750830775827
GO:0030414	peptidase inhibitor activity	45/4208	169/18639	0.266272189349112	1.17943140144442	0.121474399360883	0.318756258745733
GO:0035254	glutamate receptor binding	15/4208	49/18639	0.306122448979592	1.35594494451773	0.121519981340016	0.318756258745733
GO:0005178	integrin binding	43/4208	161/18639	0.267080745341615	1.1830128356517	0.123095605853275	0.32226949401894
GO:0030332	cyclin binding	11/4208	34/18639	0.323529411764706	1.43304769626482	0.124900875389236	0.326369337223981
GO:0043274	phospholipase binding	8/4208	23/18639	0.347826086956522	1.54066787898826	0.126611337157559	0.329576076112424
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	8/4208	23/18639	0.347826086956522	1.54066787898826	0.126611337157559	0.329576076112424
GO:0000062	fatty-acyl-CoA binding	6/4208	16/18639	0.375	1.66103255703422	0.130983958837254	0.332536799782721
GO:0005149	interleukin-1 receptor binding	6/4208	16/18639	0.375	1.66103255703422	0.130983958837254	0.332536799782721
GO:0005159	insulin-like growth factor receptor binding	6/4208	16/18639	0.375	1.66103255703422	0.130983958837254	0.332536799782721
GO:0005521	lamin binding	6/4208	16/18639	0.375	1.66103255703422	0.130983958837254	0.332536799782721
GO:0015378	sodium:chloride symporter activity	6/4208	16/18639	0.375	1.66103255703422	0.130983958837254	0.332536799782721
GO:0015385	sodium:proton antiporter activity	6/4208	16/18639	0.375	1.66103255703422	0.130983958837254	0.332536799782721
GO:0016722	oxidoreductase activity, acting on metal ions	6/4208	16/18639	0.375	1.66103255703422	0.130983958837254	0.332536799782721
GO:0055102	lipase inhibitor activity	6/4208	16/18639	0.375	1.66103255703422	0.130983958837254	0.332536799782721
GO:0140327	flippase activity	6/4208	16/18639	0.375	1.66103255703422	0.130983958837254	0.332536799782721
GO:0033192	calmodulin-dependent protein phosphatase activity	23/4208	81/18639	0.283950617283951	1.25773658639628	0.131893261497399	0.332536799782721
GO:0140791	histone H2AXS140 phosphatase activity	23/4208	81/18639	0.283950617283951	1.25773658639628	0.131893261497399	0.332536799782721
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	23/4208	81/18639	0.283950617283951	1.25773658639628	0.131893261497399	0.332536799782721
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	23/4208	81/18639	0.283950617283951	1.25773658639628	0.131893261497399	0.332536799782721
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	23/4208	81/18639	0.283950617283951	1.25773658639628	0.131893261497399	0.332536799782721
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	23/4208	81/18639	0.283950617283951	1.25773658639628	0.131893261497399	0.332536799782721
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	23/4208	81/18639	0.283950617283951	1.25773658639628	0.131893261497399	0.332536799782721
GO:1990439	MAP kinase serine/threonine phosphatase activity	23/4208	81/18639	0.283950617283951	1.25773658639628	0.131893261497399	0.332536799782721
GO:0005385	zinc ion transmembrane transporter activity	9/4208	27/18639	0.333333333333333	1.47647338403042	0.135160810107799	0.339519972351819
GO:0008320	protein transmembrane transporter activity	9/4208	27/18639	0.333333333333333	1.47647338403042	0.135160810107799	0.339519972351819
GO:0008408	3'-5' exonuclease activity	17/4208	58/18639	0.293103448275862	1.29827832044054	0.142570626493643	0.356818962453815
GO:0017116	single-stranded DNA helicase activity	17/4208	58/18639	0.293103448275862	1.29827832044054	0.142570626493643	0.356818962453815
GO:0001614	purinergic nucleotide receptor activity	7/4208	20/18639	0.35	1.55029705323194	0.144470758012443	0.358287479870859
GO:0015095	magnesium ion transmembrane transporter activity	7/4208	20/18639	0.35	1.55029705323194	0.144470758012443	0.358287479870859
GO:0016502	nucleotide receptor activity	7/4208	20/18639	0.35	1.55029705323194	0.144470758012443	0.358287479870859
GO:0016505	peptidase activator activity involved in apoptotic process	7/4208	20/18639	0.35	1.55029705323194	0.144470758012443	0.358287479870859
GO:0061608	nuclear import signal receptor activity	7/4208	20/18639	0.35	1.55029705323194	0.144470758012443	0.358287479870859
GO:0003678	DNA helicase activity	21/4208	74/18639	0.283783783783784	1.2569976107286	0.145660718647653	0.35933375111246
GO:0048029	monosaccharide binding	21/4208	74/18639	0.283783783783784	1.2569976107286	0.145660718647653	0.35933375111246
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	23/4208	82/18639	0.280487804878049	1.24239833534267	0.145946406243624	0.35933375111246
GO:0033549	MAP kinase phosphatase activity	23/4208	82/18639	0.280487804878049	1.24239833534267	0.145946406243624	0.35933375111246
GO:0004465	lipoprotein lipase activity	5/4208	13/18639	0.384615384615385	1.70362313541971	0.149186115085606	0.361438474203848
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	5/4208	13/18639	0.384615384615385	1.70362313541971	0.149186115085606	0.361438474203848
GO:0015651	quaternary ammonium group transmembrane transporter activity	5/4208	13/18639	0.384615384615385	1.70362313541971	0.149186115085606	0.361438474203848
GO:0017154	semaphorin receptor activity	5/4208	13/18639	0.384615384615385	1.70362313541971	0.149186115085606	0.361438474203848
GO:0061459	L-arginine transmembrane transporter activity	5/4208	13/18639	0.384615384615385	1.70362313541971	0.149186115085606	0.361438474203848
GO:0071714	icosanoid transmembrane transporter activity	5/4208	13/18639	0.384615384615385	1.70362313541971	0.149186115085606	0.361438474203848
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	5/4208	13/18639	0.384615384615385	1.70362313541971	0.149186115085606	0.361438474203848
GO:0140410	monoatomic cation:bicarbonate symporter activity	5/4208	13/18639	0.384615384615385	1.70362313541971	0.149186115085606	0.361438474203848
GO:0140852	histone ubiquitin ligase activity	5/4208	13/18639	0.384615384615385	1.70362313541971	0.149186115085606	0.361438474203848
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	12/4208	39/18639	0.307692307692308	1.36289850833577	0.150765453602049	0.364617160838998
GO:0043177	organic acid binding	49/4208	189/18639	0.259259259259259	1.14836818757921	0.153999358303907	0.368974969142669
GO:0004622	lysophospholipase activity	8/4208	24/18639	0.333333333333333	1.47647338403042	0.154190419656394	0.368974969142669
GO:0004806	triacylglycerol lipase activity	8/4208	24/18639	0.333333333333333	1.47647338403042	0.154190419656394	0.368974969142669
GO:0015149	hexose transmembrane transporter activity	8/4208	24/18639	0.333333333333333	1.47647338403042	0.154190419656394	0.368974969142669
GO:0030215	semaphorin receptor binding	8/4208	24/18639	0.333333333333333	1.47647338403042	0.154190419656394	0.368974969142669
GO:0055056	D-glucose transmembrane transporter activity	8/4208	24/18639	0.333333333333333	1.47647338403042	0.154190419656394	0.368974969142669
GO:0061749	forked DNA-dependent helicase activity	14/4208	47/18639	0.297872340425532	1.31940174743144	0.156186484257861	0.371794702491663
GO:0140359	ABC-type transporter activity	14/4208	47/18639	0.297872340425532	1.31940174743144	0.156186484257861	0.371794702491663
GO:1990518	single-stranded 3'-5' DNA helicase activity	14/4208	47/18639	0.297872340425532	1.31940174743144	0.156186484257861	0.371794702491663
GO:0070063	RNA polymerase binding	17/4208	59/18639	0.288135593220339	1.27627360314494	0.160255218433288	0.380486344146958
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	23/4208	83/18639	0.27710843373494	1.22742968069999	0.160821015372259	0.380486344146958
GO:0050698	proteoglycan sulfotransferase activity	9/4208	28/18639	0.321428571428571	1.42374219174362	0.161330214129654	0.380486344146958
GO:0051393	alpha-actinin binding	9/4208	28/18639	0.321428571428571	1.42374219174362	0.161330214129654	0.380486344146958
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	9/4208	28/18639	0.321428571428571	1.42374219174362	0.161330214129654	0.380486344146958
GO:0019838	growth factor binding	36/4208	136/18639	0.264705882352941	1.17249356967121	0.161511432009596	0.380486344146958
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	6/4208	17/18639	0.352941176470588	1.56332475956162	0.165639985281204	0.385551092019731
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	6/4208	17/18639	0.352941176470588	1.56332475956162	0.165639985281204	0.385551092019731
GO:0008429	phosphatidylethanolamine binding	6/4208	17/18639	0.352941176470588	1.56332475956162	0.165639985281204	0.385551092019731
GO:0008569	minus-end-directed microtubule motor activity	6/4208	17/18639	0.352941176470588	1.56332475956162	0.165639985281204	0.385551092019731
GO:0038191	neuropilin binding	6/4208	17/18639	0.352941176470588	1.56332475956162	0.165639985281204	0.385551092019731
GO:0045236	CXCR chemokine receptor binding	6/4208	17/18639	0.352941176470588	1.56332475956162	0.165639985281204	0.385551092019731
GO:1901567	fatty acid derivative binding	6/4208	17/18639	0.352941176470588	1.56332475956162	0.165639985281204	0.385551092019731
GO:0042910	xenobiotic transmembrane transporter activity	10/4208	32/18639	0.3125	1.38419379752852	0.166629962094951	0.387194664902068
GO:0005496	steroid binding	29/4208	108/18639	0.268518518518519	1.18938133713561	0.170309439261789	0.388419819665492
GO:0001094	TFIID-class transcription factor complex binding	4/4208	10/18639	0.4	1.7717680608365	0.17042477792684	0.388419819665492
GO:0004445	inositol-polyphosphate 5-phosphatase activity	4/4208	10/18639	0.4	1.7717680608365	0.17042477792684	0.388419819665492
GO:0016427	tRNA (cytidine) methyltransferase activity	4/4208	10/18639	0.4	1.7717680608365	0.17042477792684	0.388419819665492
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	4/4208	10/18639	0.4	1.7717680608365	0.17042477792684	0.388419819665492
GO:0035374	chondroitin sulfate binding	4/4208	10/18639	0.4	1.7717680608365	0.17042477792684	0.388419819665492
GO:0042975	peroxisome proliferator activated receptor binding	4/4208	10/18639	0.4	1.7717680608365	0.17042477792684	0.388419819665492
GO:0043422	protein kinase B binding	4/4208	10/18639	0.4	1.7717680608365	0.17042477792684	0.388419819665492
GO:0051864	histone H3K36 demethylase activity	4/4208	10/18639	0.4	1.7717680608365	0.17042477792684	0.388419819665492
GO:0071723	lipopeptide binding	4/4208	10/18639	0.4	1.7717680608365	0.17042477792684	0.388419819665492
GO:0099122	RNA polymerase II C-terminal domain binding	4/4208	10/18639	0.4	1.7717680608365	0.17042477792684	0.388419819665492
GO:0044390	ubiquitin-like protein conjugating enzyme binding	11/4208	36/18639	0.305555555555556	1.35343393536122	0.170574392946943	0.388419819665492
GO:0031406	carboxylic acid binding	48/4208	187/18639	0.25668449197861	1.13696346149936	0.175928302946081	0.396728301714396
GO:0017018	myosin phosphatase activity	23/4208	84/18639	0.273809523809524	1.21281742259642	0.17649561458843	0.396728301714396
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	7/4208	21/18639	0.333333333333333	1.47647338403042	0.17669450400328	0.396728301714396
GO:0015174	basic amino acid transmembrane transporter activity	7/4208	21/18639	0.333333333333333	1.47647338403042	0.17669450400328	0.396728301714396
GO:0035613	RNA stem-loop binding	7/4208	21/18639	0.333333333333333	1.47647338403042	0.17669450400328	0.396728301714396
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	7/4208	21/18639	0.333333333333333	1.47647338403042	0.17669450400328	0.396728301714396
GO:0009378	four-way junction helicase activity	14/4208	48/18639	0.291666666666667	1.29191421102662	0.177131624445797	0.396728301714396
GO:0032266	phosphatidylinositol-3-phosphate binding	14/4208	48/18639	0.291666666666667	1.29191421102662	0.177131624445797	0.396728301714396
GO:0036121	double-stranded DNA helicase activity	14/4208	48/18639	0.291666666666667	1.29191421102662	0.177131624445797	0.396728301714396
GO:0043138	3'-5' DNA helicase activity	14/4208	48/18639	0.291666666666667	1.29191421102662	0.177131624445797	0.396728301714396
GO:0042379	chemokine receptor binding	20/4208	72/18639	0.277777777777778	1.23039448669202	0.178482419212415	0.399098393124154
GO:0005539	glycosaminoglycan binding	61/4208	242/18639	0.252066115702479	1.11650673255193	0.181331709967416	0.404805977734132
GO:0005125	cytokine activity	59/4208	234/18639	0.252136752136752	1.11681961099737	0.185288956874348	0.41296427643237
GO:0000287	magnesium ion binding	58/4208	230/18639	0.252173913043478	1.11698421226649	0.187311396427191	0.416790774431793
GO:0008237	metallopeptidase activity	47/4208	184/18639	0.255434782608696	1.13142797363201	0.188717743723381	0.419236160323601
GO:0004065	arylsulfatase activity	5/4208	14/18639	0.357142857142857	1.58193576860402	0.191108000638567	0.420218035899556
GO:0004705	JUN kinase activity	5/4208	14/18639	0.357142857142857	1.58193576860402	0.191108000638567	0.420218035899556
GO:0008191	metalloendopeptidase inhibitor activity	5/4208	14/18639	0.357142857142857	1.58193576860402	0.191108000638567	0.420218035899556
GO:0034236	protein kinase A catalytic subunit binding	5/4208	14/18639	0.357142857142857	1.58193576860402	0.191108000638567	0.420218035899556
GO:0046030	inositol trisphosphate phosphatase activity	5/4208	14/18639	0.357142857142857	1.58193576860402	0.191108000638567	0.420218035899556
GO:0061665	SUMO ligase activity	5/4208	14/18639	0.357142857142857	1.58193576860402	0.191108000638567	0.420218035899556
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	24/4208	89/18639	0.269662921348315	1.19445037809202	0.19162435361402	0.420218035899556
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	24/4208	89/18639	0.269662921348315	1.19445037809202	0.19162435361402	0.420218035899556
GO:0008009	chemokine activity	13/4208	45/18639	0.288888888888889	1.2796102661597	0.198831346027786	0.434060390013376
GO:0015026	coreceptor activity	17/4208	61/18639	0.278688524590164	1.23442856697625	0.198891307740733	0.434060390013376
GO:0019905	syntaxin binding	17/4208	61/18639	0.278688524590164	1.23442856697625	0.198891307740733	0.434060390013376
GO:0051018	protein kinase A binding	15/4208	53/18639	0.283018867924528	1.25360947700696	0.199516186154066	0.434728558968284
GO:0008013	beta-catenin binding	28/4208	106/18639	0.264150943396226	1.17003551187316	0.200966614068475	0.437190528850717
GO:0008308	voltage-gated monoatomic anion channel activity	6/4208	18/18639	0.333333333333333	1.47647338403042	0.203657645049534	0.44023617725446
GO:0015373	monoatomic anion:sodium symporter activity	6/4208	18/18639	0.333333333333333	1.47647338403042	0.203657645049534	0.44023617725446
GO:0016854	racemase and epimerase activity	6/4208	18/18639	0.333333333333333	1.47647338403042	0.203657645049534	0.44023617725446
GO:0017075	syntaxin-1 binding	6/4208	18/18639	0.333333333333333	1.47647338403042	0.203657645049534	0.44023617725446
GO:0004725	protein tyrosine phosphatase activity	26/4208	98/18639	0.26530612244898	1.1751522852487	0.204675884626738	0.441737194036187
GO:0140793	histone H2AXY142 phosphatase activity	24/4208	90/18639	0.266666666666667	1.18117870722433	0.20833334043075	0.448920499759152
GO:0016881	acid-amino acid ligase activity	7/4208	22/18639	0.318181818181818	1.40936095748358	0.211628312378501	0.453869525289741
GO:0050321	tau-protein kinase activity	7/4208	22/18639	0.318181818181818	1.40936095748358	0.211628312378501	0.453869525289741
GO:0061133	endopeptidase activator activity	7/4208	22/18639	0.318181818181818	1.40936095748358	0.211628312378501	0.453869525289741
GO:0001637	G protein-coupled chemoattractant receptor activity	8/4208	26/18639	0.307692307692308	1.36289850833577	0.216767811919443	0.461986399153312
GO:0004950	chemokine receptor activity	8/4208	26/18639	0.307692307692308	1.36289850833577	0.216767811919443	0.461986399153312
GO:0008198	ferrous iron binding	8/4208	26/18639	0.307692307692308	1.36289850833577	0.216767811919443	0.461986399153312
GO:0030247	polysaccharide binding	8/4208	26/18639	0.307692307692308	1.36289850833577	0.216767811919443	0.461986399153312
GO:0004722	protein serine/threonine phosphatase activity	27/4208	103/18639	0.262135922330097	1.16111013695596	0.218869652495851	0.462465201113855
GO:0031210	phosphatidylcholine binding	9/4208	30/18639	0.3	1.32882604562738	0.220040441321447	0.462465201113855
GO:0140463	chromatin-protein adaptor activity	15/4208	54/18639	0.277777777777778	1.23039448669202	0.222007362573199	0.462465201113855
GO:0008175	tRNA methyltransferase activity	10/4208	34/18639	0.294117647058824	1.30277063296802	0.222023333436517	0.462465201113855
GO:0008376	acetylgalactosaminyltransferase activity	10/4208	34/18639	0.294117647058824	1.30277063296802	0.222023333436517	0.462465201113855
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	4/4208	11/18639	0.363636363636364	1.61069823712409	0.222417281474112	0.462465201113855
GO:0005114	type II transforming growth factor beta receptor binding	4/4208	11/18639	0.363636363636364	1.61069823712409	0.222417281474112	0.462465201113855
GO:0008199	ferric iron binding	4/4208	11/18639	0.363636363636364	1.61069823712409	0.222417281474112	0.462465201113855
GO:0019203	carbohydrate phosphatase activity	4/4208	11/18639	0.363636363636364	1.61069823712409	0.222417281474112	0.462465201113855
GO:0032050	clathrin heavy chain binding	4/4208	11/18639	0.363636363636364	1.61069823712409	0.222417281474112	0.462465201113855
GO:0032794	GTPase activating protein binding	4/4208	11/18639	0.363636363636364	1.61069823712409	0.222417281474112	0.462465201113855
GO:0034713	type I transforming growth factor beta receptor binding	4/4208	11/18639	0.363636363636364	1.61069823712409	0.222417281474112	0.462465201113855
GO:0042608	T cell receptor binding	4/4208	11/18639	0.363636363636364	1.61069823712409	0.222417281474112	0.462465201113855
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	4/4208	11/18639	0.363636363636364	1.61069823712409	0.222417281474112	0.462465201113855
GO:0070990	snRNP binding	4/4208	11/18639	0.363636363636364	1.61069823712409	0.222417281474112	0.462465201113855
GO:0097493	structural molecule activity conferring elasticity	4/4208	11/18639	0.363636363636364	1.61069823712409	0.222417281474112	0.462465201113855
GO:0004867	serine-type endopeptidase inhibitor activity	25/4208	95/18639	0.263157894736842	1.16563688212928	0.223424323209979	0.463852019571403
GO:0072341	modified amino acid binding	24/4208	91/18639	0.263736263736264	1.16819872143066	0.225715468771748	0.467896503654504
GO:0004175	endopeptidase activity	98/4208	405/18639	0.241975308641975	1.07181030840727	0.231532902634167	0.479227434283769
GO:0033293	monocarboxylic acid binding	21/4208	79/18639	0.265822784810127	1.17744079992299	0.23259085763105	0.480687772437502
GO:0004467	long-chain fatty acid-CoA ligase activity	5/4208	15/18639	0.333333333333333	1.47647338403042	0.236554250669317	0.483748122808018
GO:0005041	low-density lipoprotein particle receptor activity	5/4208	15/18639	0.333333333333333	1.47647338403042	0.236554250669317	0.483748122808018
GO:0005523	tropomyosin binding	5/4208	15/18639	0.333333333333333	1.47647338403042	0.236554250669317	0.483748122808018
GO:0030553	cGMP binding	5/4208	15/18639	0.333333333333333	1.47647338403042	0.236554250669317	0.483748122808018
GO:0051371	muscle alpha-actinin binding	5/4208	15/18639	0.333333333333333	1.47647338403042	0.236554250669317	0.483748122808018
GO:0140161	monocarboxylate:sodium symporter activity	5/4208	15/18639	0.333333333333333	1.47647338403042	0.236554250669317	0.483748122808018
GO:0140776	protein-containing complex destabilizing activity	5/4208	15/18639	0.333333333333333	1.47647338403042	0.236554250669317	0.483748122808018
GO:0015459	potassium channel regulator activity	16/4208	59/18639	0.271186440677966	1.20119868531288	0.243544274063913	0.493907063603034
GO:0030506	ankyrin binding	6/4208	19/18639	0.315789473684211	1.39876425855513	0.244418818132	0.493907063603034
GO:0031420	alkali metal ion binding	6/4208	19/18639	0.315789473684211	1.39876425855513	0.244418818132	0.493907063603034
GO:0042577	lipid phosphatase activity	6/4208	19/18639	0.315789473684211	1.39876425855513	0.244418818132	0.493907063603034
GO:0043395	heparan sulfate proteoglycan binding	6/4208	19/18639	0.315789473684211	1.39876425855513	0.244418818132	0.493907063603034
GO:0050145	nucleoside monophosphate kinase activity	6/4208	19/18639	0.315789473684211	1.39876425855513	0.244418818132	0.493907063603034
GO:0097001	ceramide binding	6/4208	19/18639	0.315789473684211	1.39876425855513	0.244418818132	0.493907063603034
GO:0120227	acyl-CoA binding	6/4208	19/18639	0.315789473684211	1.39876425855513	0.244418818132	0.493907063603034
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	7/4208	23/18639	0.304347826086957	1.34808439411473	0.248823239037663	0.498377236486597
GO:0016493	C-C chemokine receptor activity	7/4208	23/18639	0.304347826086957	1.34808439411473	0.248823239037663	0.498377236486597
GO:0016849	phosphorus-oxygen lyase activity	7/4208	23/18639	0.304347826086957	1.34808439411473	0.248823239037663	0.498377236486597
GO:0031681	G-protein beta-subunit binding	7/4208	23/18639	0.304347826086957	1.34808439411473	0.248823239037663	0.498377236486597
GO:0042171	lysophosphatidic acid acyltransferase activity	7/4208	23/18639	0.304347826086957	1.34808439411473	0.248823239037663	0.498377236486597
GO:0071617	lysophospholipid acyltransferase activity	7/4208	23/18639	0.304347826086957	1.34808439411473	0.248823239037663	0.498377236486597
GO:0016298	lipase activity	33/4208	130/18639	0.253846153846154	1.12439126937701	0.250224341787031	0.500110299416193
GO:0005245	voltage-gated calcium channel activity	12/4208	43/18639	0.27906976744186	1.2361172517464	0.250421799487727	0.500110299416193
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	8/4208	27/18639	0.296296296296296	1.31242078580482	0.251128654787502	0.500543326157898
GO:0008327	methyl-CpG binding	9/4208	31/18639	0.290322580645161	1.28596068931682	0.252076743337584	0.500543326157898
GO:0070273	phosphatidylinositol-4-phosphate binding	9/4208	31/18639	0.290322580645161	1.28596068931682	0.252076743337584	0.500543326157898
GO:0140566	histone reader activity	10/4208	35/18639	0.285714285714286	1.26554861488322	0.252106499318531	0.500543326157898
GO:0140098	catalytic activity, acting on RNA	93/4208	387/18639	0.24031007751938	1.06443430011495	0.26216295967843	0.519753309595027
GO:0004222	metalloendopeptidase activity	28/4208	110/18639	0.254545454545455	1.12748876598686	0.266778030895824	0.528135318057916
GO:0019212	phosphatase inhibitor activity	15/4208	56/18639	0.267857142857143	1.18645182645301	0.269945203716566	0.533630808506371
GO:0030971	receptor tyrosine kinase binding	21/4208	81/18639	0.259259259259259	1.14836818757921	0.272609315392108	0.537421907926024
GO:0004875	complement receptor activity	4/4208	12/18639	0.333333333333333	1.47647338403042	0.277773053583466	0.537421907926024
GO:0005247	voltage-gated chloride channel activity	4/4208	12/18639	0.333333333333333	1.47647338403042	0.277773053583466	0.537421907926024
GO:0005527	macrolide binding	4/4208	12/18639	0.333333333333333	1.47647338403042	0.277773053583466	0.537421907926024
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	4/4208	12/18639	0.333333333333333	1.47647338403042	0.277773053583466	0.537421907926024
GO:0008603	cAMP-dependent protein kinase regulator activity	4/4208	12/18639	0.333333333333333	1.47647338403042	0.277773053583466	0.537421907926024
GO:0015132	prostaglandin transmembrane transporter activity	4/4208	12/18639	0.333333333333333	1.47647338403042	0.277773053583466	0.537421907926024
GO:0016840	carbon-nitrogen lyase activity	4/4208	12/18639	0.333333333333333	1.47647338403042	0.277773053583466	0.537421907926024
GO:0017166	vinculin binding	4/4208	12/18639	0.333333333333333	1.47647338403042	0.277773053583466	0.537421907926024
GO:0034452	dynactin binding	4/4208	12/18639	0.333333333333333	1.47647338403042	0.277773053583466	0.537421907926024
GO:0035014	phosphatidylinositol 3-kinase regulator activity	4/4208	12/18639	0.333333333333333	1.47647338403042	0.277773053583466	0.537421907926024
GO:0035497	cAMP response element binding	4/4208	12/18639	0.333333333333333	1.47647338403042	0.277773053583466	0.537421907926024
GO:0045295	gamma-catenin binding	4/4208	12/18639	0.333333333333333	1.47647338403042	0.277773053583466	0.537421907926024
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	4/4208	12/18639	0.333333333333333	1.47647338403042	0.277773053583466	0.537421907926024
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	4/4208	12/18639	0.333333333333333	1.47647338403042	0.277773053583466	0.537421907926024
GO:0140789	histone phosphatase activity	34/4208	136/18639	0.25	1.10735503802281	0.278326919518313	0.537730762355493
GO:0050997	quaternary ammonium group binding	11/4208	40/18639	0.275	1.2180905418251	0.28108024522121	0.542189423647846
GO:0004707	MAP kinase activity	5/4208	16/18639	0.3125	1.38419379752852	0.284540746956618	0.542189423647846
GO:0004708	MAP kinase kinase activity	5/4208	16/18639	0.3125	1.38419379752852	0.284540746956618	0.542189423647846
GO:0015923	mannosidase activity	5/4208	16/18639	0.3125	1.38419379752852	0.284540746956618	0.542189423647846
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	5/4208	16/18639	0.3125	1.38419379752852	0.284540746956618	0.542189423647846
GO:0034450	ubiquitin-ubiquitin ligase activity	5/4208	16/18639	0.3125	1.38419379752852	0.284540746956618	0.542189423647846
GO:0043425	bHLH transcription factor binding	9/4208	32/18639	0.28125	1.24577441777567	0.285512440345571	0.542189423647846
GO:0019789	SUMO transferase activity	8/4208	28/18639	0.285714285714286	1.26554861488322	0.287048031050642	0.542189423647846
GO:0045499	chemorepellent activity	8/4208	28/18639	0.285714285714286	1.26554861488322	0.287048031050642	0.542189423647846
GO:0046625	sphingolipid binding	8/4208	28/18639	0.285714285714286	1.26554861488322	0.287048031050642	0.542189423647846
GO:0000339	RNA cap binding	6/4208	20/18639	0.3	1.32882604562738	0.287253701040381	0.542189423647846
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	6/4208	20/18639	0.3	1.32882604562738	0.287253701040381	0.542189423647846
GO:0160215	deacylase activity	17/4208	65/18639	0.261538461538462	1.1584637320854	0.287339652595824	0.542189423647846
GO:0005315	phosphate transmembrane transporter activity	7/4208	24/18639	0.291666666666667	1.29191421102662	0.287789694077009	0.542189423647846
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	7/4208	24/18639	0.291666666666667	1.29191421102662	0.287789694077009	0.542189423647846
GO:0050431	transforming growth factor beta binding	7/4208	24/18639	0.291666666666667	1.29191421102662	0.287789694077009	0.542189423647846
GO:0070840	dynein complex binding	7/4208	24/18639	0.291666666666667	1.29191421102662	0.287789694077009	0.542189423647846
GO:0140033	acetylation-dependent protein binding	7/4208	24/18639	0.291666666666667	1.29191421102662	0.287789694077009	0.542189423647846
GO:0141110	transporter inhibitor activity	12/4208	45/18639	0.266666666666667	1.18117870722433	0.307431050625515	0.578394418004418
GO:0001664	G protein-coupled receptor binding	71/4208	297/18639	0.239057239057239	1.05888495218343	0.311414020308165	0.584674996025693
GO:0001530	lipopolysaccharide binding	11/4208	41/18639	0.268292682926829	1.18838101641473	0.311626629113401	0.584674996025693
GO:0016798	hydrolase activity, acting on glycosyl bonds	32/4208	130/18639	0.246153846153846	1.09031880666862	0.320020701638581	0.599599226696461
GO:0004629	phospholipase C activity	8/4208	29/18639	0.275862068965517	1.22190900747345	0.324132488724642	0.604810827114105
GO:0035250	UDP-galactosyltransferase activity	8/4208	29/18639	0.275862068965517	1.22190900747345	0.324132488724642	0.604810827114105
GO:0043236	laminin binding	8/4208	29/18639	0.275862068965517	1.22190900747345	0.324132488724642	0.604810827114105
GO:0043178	alcohol binding	23/4208	92/18639	0.25	1.10735503802281	0.326162820532823	0.606686194811118
GO:0015662	P-type ion transporter activity	7/4208	25/18639	0.28	1.24023764258555	0.32801979402774	0.606686194811118
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	7/4208	25/18639	0.28	1.24023764258555	0.32801979402774	0.606686194811118
GO:0017025	TBP-class protein binding	7/4208	25/18639	0.28	1.24023764258555	0.32801979402774	0.606686194811118
GO:0140358	P-type transmembrane transporter activity	7/4208	25/18639	0.28	1.24023764258555	0.32801979402774	0.606686194811118
GO:0010314	phosphatidylinositol-5-phosphate binding	6/4208	21/18639	0.285714285714286	1.26554861488322	0.331477379855222	0.606686194811118
GO:0004659	prenyltransferase activity	5/4208	17/18639	0.294117647058824	1.30277063296802	0.33408273098804	0.606686194811118
GO:0032183	SUMO binding	5/4208	17/18639	0.294117647058824	1.30277063296802	0.33408273098804	0.606686194811118
GO:0045125	bioactive lipid receptor activity	5/4208	17/18639	0.294117647058824	1.30277063296802	0.33408273098804	0.606686194811118
GO:0048038	quinone binding	5/4208	17/18639	0.294117647058824	1.30277063296802	0.33408273098804	0.606686194811118
GO:0008253	5'-nucleotidase activity	4/4208	13/18639	0.307692307692308	1.36289850833577	0.334922804026959	0.606686194811118
GO:0019855	calcium channel inhibitor activity	4/4208	13/18639	0.307692307692308	1.36289850833577	0.334922804026959	0.606686194811118
GO:0030955	potassium ion binding	4/4208	13/18639	0.307692307692308	1.36289850833577	0.334922804026959	0.606686194811118
GO:0035325	Toll-like receptor binding	4/4208	13/18639	0.307692307692308	1.36289850833577	0.334922804026959	0.606686194811118
GO:0035673	oligopeptide transmembrane transporter activity	4/4208	13/18639	0.307692307692308	1.36289850833577	0.334922804026959	0.606686194811118
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	4/4208	13/18639	0.307692307692308	1.36289850833577	0.334922804026959	0.606686194811118
GO:0046974	histone H3K9 methyltransferase activity	4/4208	13/18639	0.307692307692308	1.36289850833577	0.334922804026959	0.606686194811118
GO:0051011	microtubule minus-end binding	4/4208	13/18639	0.307692307692308	1.36289850833577	0.334922804026959	0.606686194811118
GO:0070123	transforming growth factor beta receptor activity, type III	4/4208	13/18639	0.307692307692308	1.36289850833577	0.334922804026959	0.606686194811118
GO:0089720	caspase binding	4/4208	13/18639	0.307692307692308	1.36289850833577	0.334922804026959	0.606686194811118
GO:0097157	pre-mRNA intronic binding	4/4208	13/18639	0.307692307692308	1.36289850833577	0.334922804026959	0.606686194811118
GO:1901338	catecholamine binding	4/4208	13/18639	0.307692307692308	1.36289850833577	0.334922804026959	0.606686194811118
GO:0005507	copper ion binding	16/4208	63/18639	0.253968253968254	1.12493210211841	0.341480031822041	0.617743718044116
GO:0019894	kinesin binding	11/4208	42/18639	0.261904761904762	1.16008623030961	0.3429096277218	0.619508254586139
GO:0042162	telomeric DNA binding	10/4208	38/18639	0.263157894736842	1.16563688212928	0.348968802367835	0.629620960885883
GO:0004721	phosphoprotein phosphatase activity	42/4208	175/18639	0.24	1.0630608365019	0.353540809165521	0.636562848061504
GO:0098632	cell-cell adhesion mediator activity	14/4208	55/18639	0.254545454545455	1.12748876598686	0.353749735213064	0.636562848061504
GO:0015035	protein-disulfide reductase activity	9/4208	34/18639	0.264705882352941	1.17249356967121	0.355316332063539	0.637699311756142
GO:0052866	phosphatidylinositol phosphate phosphatase activity	9/4208	34/18639	0.264705882352941	1.17249356967121	0.355316332063539	0.637699311756142
GO:0008238	exopeptidase activity	25/4208	102/18639	0.245098039215686	1.08564219414001	0.356353221680637	0.638719834917726
GO:0003777	microtubule motor activity	17/4208	68/18639	0.25	1.10735503802281	0.360634606283367	0.644699348585206
GO:0030145	manganese ion binding	17/4208	68/18639	0.25	1.10735503802281	0.360634606283367	0.644699348585206
GO:0005504	fatty acid binding	12/4208	47/18639	0.25531914893617	1.13091578351266	0.367315374561674	0.653670191879215
GO:0004435	phosphatidylinositol phospholipase C activity	7/4208	26/18639	0.269230769230769	1.1925361947938	0.369007366383428	0.653670191879215
GO:0004529	DNA exonuclease activity	7/4208	26/18639	0.269230769230769	1.1925361947938	0.369007366383428	0.653670191879215
GO:0019865	immunoglobulin binding	7/4208	26/18639	0.269230769230769	1.1925361947938	0.369007366383428	0.653670191879215
GO:0034237	protein kinase A regulatory subunit binding	7/4208	26/18639	0.269230769230769	1.1925361947938	0.369007366383428	0.653670191879215
GO:0050750	low-density lipoprotein particle receptor binding	7/4208	26/18639	0.269230769230769	1.1925361947938	0.369007366383428	0.653670191879215
GO:0120014	phospholipid transfer activity	7/4208	26/18639	0.269230769230769	1.1925361947938	0.369007366383428	0.653670191879215
GO:0008093	cytoskeletal anchor activity	6/4208	22/18639	0.272727272727273	1.20802367784307	0.376420780158992	0.664214675468131
GO:0008970	phospholipase A1 activity	6/4208	22/18639	0.272727272727273	1.20802367784307	0.376420780158992	0.664214675468131
GO:0031683	G-protein beta/gamma-subunit complex binding	6/4208	22/18639	0.272727272727273	1.20802367784307	0.376420780158992	0.664214675468131
GO:0016209	antioxidant activity	21/4208	86/18639	0.244186046511628	1.0816025952781	0.381441284015748	0.669081364709425
GO:0030170	pyridoxal phosphate binding	14/4208	56/18639	0.25	1.10735503802281	0.38168457904523	0.669081364709425
GO:0170055	lipid transmembrane transporter activity	14/4208	56/18639	0.25	1.10735503802281	0.38168457904523	0.669081364709425
GO:0000400	four-way junction DNA binding	5/4208	18/18639	0.277777777777778	1.23039448669202	0.384246225579774	0.669081364709425
GO:0003746	translation elongation factor activity	5/4208	18/18639	0.277777777777778	1.23039448669202	0.384246225579774	0.669081364709425
GO:0008409	5'-3' exonuclease activity	5/4208	18/18639	0.277777777777778	1.23039448669202	0.384246225579774	0.669081364709425
GO:0017128	phospholipid scramblase activity	5/4208	18/18639	0.277777777777778	1.23039448669202	0.384246225579774	0.669081364709425
GO:0050811	GABA receptor binding	5/4208	18/18639	0.277777777777778	1.23039448669202	0.384246225579774	0.669081364709425
GO:1990381	ubiquitin-specific protease binding	5/4208	18/18639	0.277777777777778	1.23039448669202	0.384246225579774	0.669081364709425
GO:0005200	structural constituent of cytoskeleton	27/4208	112/18639	0.241071428571429	1.06780664380771	0.384349703903064	0.669081364709425
GO:0016229	steroid dehydrogenase activity	9/4208	35/18639	0.257142857142857	1.13899375339489	0.391042812629119	0.669081364709425
GO:0005313	L-glutamate transmembrane transporter activity	4/4208	14/18639	0.285714285714286	1.26554861488322	0.392448725382315	0.669081364709425
GO:0008195	phosphatidate phosphatase activity	4/4208	14/18639	0.285714285714286	1.26554861488322	0.392448725382315	0.669081364709425
GO:0008331	high voltage-gated calcium channel activity	4/4208	14/18639	0.285714285714286	1.26554861488322	0.392448725382315	0.669081364709425
GO:0008494	translation activator activity	4/4208	14/18639	0.285714285714286	1.26554861488322	0.392448725382315	0.669081364709425
GO:0015386	potassium:proton antiporter activity	4/4208	14/18639	0.285714285714286	1.26554861488322	0.392448725382315	0.669081364709425
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	4/4208	14/18639	0.285714285714286	1.26554861488322	0.392448725382315	0.669081364709425
GO:0043176	amine binding	4/4208	14/18639	0.285714285714286	1.26554861488322	0.392448725382315	0.669081364709425
GO:0070742	C2H2 zinc finger domain binding	4/4208	14/18639	0.285714285714286	1.26554861488322	0.392448725382315	0.669081364709425
GO:0071933	Arp2/3 complex binding	4/4208	14/18639	0.285714285714286	1.26554861488322	0.392448725382315	0.669081364709425
GO:0098847	sequence-specific single stranded DNA binding	4/4208	14/18639	0.285714285714286	1.26554861488322	0.392448725382315	0.669081364709425
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	22/4208	91/18639	0.241758241758242	1.07084882797811	0.396869083297616	0.669081364709425
GO:0005452	solute:inorganic anion antiporter activity	8/4208	31/18639	0.258064516129032	1.14307616828161	0.400212802843445	0.669081364709425
GO:0003680	minor groove of adenine-thymine-rich DNA binding	3/4208	10/18639	0.3	1.32882604562738	0.400762078421994	0.669081364709425
GO:0004382	GDP phosphatase activity	3/4208	10/18639	0.3	1.32882604562738	0.400762078421994	0.669081364709425
GO:0004862	cAMP-dependent protein kinase inhibitor activity	3/4208	10/18639	0.3	1.32882604562738	0.400762078421994	0.669081364709425
GO:0004935	adrenergic receptor activity	3/4208	10/18639	0.3	1.32882604562738	0.400762078421994	0.669081364709425
GO:0005337	nucleoside transmembrane transporter activity	3/4208	10/18639	0.3	1.32882604562738	0.400762078421994	0.669081364709425
GO:0005345	purine nucleobase transmembrane transporter activity	3/4208	10/18639	0.3	1.32882604562738	0.400762078421994	0.669081364709425
GO:0005528	FK506 binding	3/4208	10/18639	0.3	1.32882604562738	0.400762078421994	0.669081364709425
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	3/4208	10/18639	0.3	1.32882604562738	0.400762078421994	0.669081364709425
GO:0015187	glycine transmembrane transporter activity	3/4208	10/18639	0.3	1.32882604562738	0.400762078421994	0.669081364709425
GO:0015203	polyamine transmembrane transporter activity	3/4208	10/18639	0.3	1.32882604562738	0.400762078421994	0.669081364709425
GO:0015279	store-operated calcium channel activity	3/4208	10/18639	0.3	1.32882604562738	0.400762078421994	0.669081364709425
GO:0015643	toxic substance binding	3/4208	10/18639	0.3	1.32882604562738	0.400762078421994	0.669081364709425
GO:0015924	mannosyl-oligosaccharide mannosidase activity	3/4208	10/18639	0.3	1.32882604562738	0.400762078421994	0.669081364709425
GO:0016175	superoxide-generating NAD(P)H oxidase activity	3/4208	10/18639	0.3	1.32882604562738	0.400762078421994	0.669081364709425
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	3/4208	10/18639	0.3	1.32882604562738	0.400762078421994	0.669081364709425
GO:0031419	cobalamin binding	3/4208	10/18639	0.3	1.32882604562738	0.400762078421994	0.669081364709425
GO:0031434	mitogen-activated protein kinase kinase binding	3/4208	10/18639	0.3	1.32882604562738	0.400762078421994	0.669081364709425
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	3/4208	10/18639	0.3	1.32882604562738	0.400762078421994	0.669081364709425
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	3/4208	10/18639	0.3	1.32882604562738	0.400762078421994	0.669081364709425
GO:0050308	sugar-phosphatase activity	3/4208	10/18639	0.3	1.32882604562738	0.400762078421994	0.669081364709425
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	3/4208	10/18639	0.3	1.32882604562738	0.400762078421994	0.669081364709425
GO:0140767	enzyme-substrate adaptor activity	33/4208	139/18639	0.237410071942446	1.05158895697131	0.403179845172395	0.671581241083741
GO:0003684	damaged DNA binding	18/4208	74/18639	0.243243243243243	1.07742652348166	0.403244161618463	0.671581241083741
GO:0016248	channel inhibitor activity	11/4208	44/18639	0.25	1.10735503802281	0.406779381769864	0.676642776504994
GO:0070279	vitamin B6 binding	14/4208	57/18639	0.245614035087719	1.08792775665399	0.409854174164623	0.680748774614312
GO:0016405	CoA-ligase activity	7/4208	27/18639	0.259259259259259	1.14836818757921	0.410264915442002	0.680748774614312
GO:0004620	phospholipase activity	26/4208	109/18639	0.238532110091743	1.05655893536122	0.41110971779414	0.680748774614312
GO:0008028	monocarboxylic acid transmembrane transporter activity	17/4208	70/18639	0.242857142857143	1.07571632265073	0.411244127772869	0.680748774614312
GO:1901681	sulfur compound binding	64/4208	275/18639	0.232727272727273	1.03084687175942	0.413745950004587	0.684059970674251
GO:0004864	protein phosphatase inhibitor activity	13/4208	53/18639	0.245283018867925	1.08646154673936	0.418868852496639	0.689188317014977
GO:0005544	calcium-dependent phospholipid binding	13/4208	53/18639	0.245283018867925	1.08646154673936	0.418868852496639	0.689188317014977
GO:0017046	peptide hormone binding	13/4208	53/18639	0.245283018867925	1.08646154673936	0.418868852496639	0.689188317014977
GO:0038064	collagen receptor activity	13/4208	53/18639	0.245283018867925	1.08646154673936	0.418868852496639	0.689188317014977
GO:0070577	lysine-acetylated histone binding	6/4208	23/18639	0.260869565217391	1.1555009092412	0.421455206437108	0.692608315156886
GO:0004869	cysteine-type endopeptidase inhibitor activity	9/4208	36/18639	0.25	1.10735503802281	0.426902082915778	0.699032942493544
GO:0016409	palmitoyltransferase activity	9/4208	36/18639	0.25	1.10735503802281	0.426902082915778	0.699032942493544
GO:0045505	dynein intermediate chain binding	9/4208	36/18639	0.25	1.10735503802281	0.426902082915778	0.699032942493544
GO:0008194	UDP-glycosyltransferase activity	34/4208	145/18639	0.23448275862069	1.03862265635243	0.432547261051427	0.703358401973632
GO:0008301	DNA binding, bending	5/4208	19/18639	0.263157894736842	1.16563688212928	0.43418458538255	0.703358401973632
GO:0015245	fatty acid transmembrane transporter activity	5/4208	19/18639	0.263157894736842	1.16563688212928	0.43418458538255	0.703358401973632
GO:0022840	leak channel activity	5/4208	19/18639	0.263157894736842	1.16563688212928	0.43418458538255	0.703358401973632
GO:0022842	narrow pore channel activity	5/4208	19/18639	0.263157894736842	1.16563688212928	0.43418458538255	0.703358401973632
GO:0042834	peptidoglycan binding	5/4208	19/18639	0.263157894736842	1.16563688212928	0.43418458538255	0.703358401973632
GO:0046527	glucosyltransferase activity	5/4208	19/18639	0.263157894736842	1.16563688212928	0.43418458538255	0.703358401973632
GO:0046624	sphingolipid transporter activity	5/4208	19/18639	0.263157894736842	1.16563688212928	0.43418458538255	0.703358401973632
GO:0140036	ubiquitin-modified protein reader activity	5/4208	19/18639	0.263157894736842	1.16563688212928	0.43418458538255	0.703358401973632
GO:0008378	galactosyltransferase activity	8/4208	32/18639	0.25	1.10735503802281	0.438446257009404	0.707740466935889
GO:0030515	snoRNA binding	8/4208	32/18639	0.25	1.10735503802281	0.438446257009404	0.707740466935889
GO:0031369	translation initiation factor binding	8/4208	32/18639	0.25	1.10735503802281	0.438446257009404	0.707740466935889
GO:0008201	heparin binding	40/4208	172/18639	0.232558139534884	1.03009770978866	0.444846366505304	0.714846815494895
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	16/4208	67/18639	0.238805970149254	1.05777197661881	0.446015790902863	0.714846815494895
GO:0050840	extracellular matrix binding	16/4208	67/18639	0.238805970149254	1.05777197661881	0.446015790902863	0.714846815494895
GO:0004559	alpha-mannosidase activity	4/4208	15/18639	0.266666666666667	1.18117870722433	0.449137625277951	0.714846815494895
GO:0008252	nucleotidase activity	4/4208	15/18639	0.266666666666667	1.18117870722433	0.449137625277951	0.714846815494895
GO:0015556	C4-dicarboxylate transmembrane transporter activity	4/4208	15/18639	0.266666666666667	1.18117870722433	0.449137625277951	0.714846815494895
GO:0015929	hexosaminidase activity	4/4208	15/18639	0.266666666666667	1.18117870722433	0.449137625277951	0.714846815494895
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	4/4208	15/18639	0.266666666666667	1.18117870722433	0.449137625277951	0.714846815494895
GO:0034483	heparan sulfate sulfotransferase activity	4/4208	15/18639	0.266666666666667	1.18117870722433	0.449137625277951	0.714846815494895
GO:0048531	beta-1,3-galactosyltransferase activity	4/4208	15/18639	0.266666666666667	1.18117870722433	0.449137625277951	0.714846815494895
GO:0141050	histone H3K deacetylase activity	4/4208	15/18639	0.266666666666667	1.18117870722433	0.449137625277951	0.714846815494895
GO:0141051	histone H4K deacetylase activity	4/4208	15/18639	0.266666666666667	1.18117870722433	0.449137625277951	0.714846815494895
GO:0017022	myosin binding	18/4208	76/18639	0.236842105263158	1.04907319391635	0.452725375600998	0.719717263775945
GO:0048020	CCR chemokine receptor binding	12/4208	50/18639	0.24	1.0630608365019	0.459143604308848	0.722381470675473
GO:0005540	hyaluronic acid binding	6/4208	24/18639	0.25	1.10735503802281	0.466010377223808	0.722381470675473
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	6/4208	24/18639	0.25	1.10735503802281	0.466010377223808	0.722381470675473
GO:0036002	pre-mRNA binding	14/4208	59/18639	0.23728813559322	1.05104884964877	0.466308769379484	0.722381470675473
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	3/4208	11/18639	0.272727272727273	1.20802367784307	0.467641377277451	0.722381470675473
GO:0001851	complement component C3b binding	3/4208	11/18639	0.272727272727273	1.20802367784307	0.467641377277451	0.722381470675473
GO:0004016	adenylate cyclase activity	3/4208	11/18639	0.272727272727273	1.20802367784307	0.467641377277451	0.722381470675473
GO:0005221	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	3/4208	11/18639	0.272727272727273	1.20802367784307	0.467641377277451	0.722381470675473
GO:0008046	axon guidance receptor activity	3/4208	11/18639	0.272727272727273	1.20802367784307	0.467641377277451	0.722381470675473
GO:0010854	adenylate cyclase regulator activity	3/4208	11/18639	0.272727272727273	1.20802367784307	0.467641377277451	0.722381470675473
GO:0015205	nucleobase transmembrane transporter activity	3/4208	11/18639	0.272727272727273	1.20802367784307	0.467641377277451	0.722381470675473
GO:0015217	ADP transmembrane transporter activity	3/4208	11/18639	0.272727272727273	1.20802367784307	0.467641377277451	0.722381470675473
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	3/4208	11/18639	0.272727272727273	1.20802367784307	0.467641377277451	0.722381470675473
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	3/4208	11/18639	0.272727272727273	1.20802367784307	0.467641377277451	0.722381470675473
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	3/4208	11/18639	0.272727272727273	1.20802367784307	0.467641377277451	0.722381470675473
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	3/4208	11/18639	0.272727272727273	1.20802367784307	0.467641377277451	0.722381470675473
GO:0019107	myristoyltransferase activity	3/4208	11/18639	0.272727272727273	1.20802367784307	0.467641377277451	0.722381470675473
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	3/4208	11/18639	0.272727272727273	1.20802367784307	0.467641377277451	0.722381470675473
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	3/4208	11/18639	0.272727272727273	1.20802367784307	0.467641377277451	0.722381470675473
GO:0043855	cyclic nucleotide-activated monoatomic ion channel activity	3/4208	11/18639	0.272727272727273	1.20802367784307	0.467641377277451	0.722381470675473
GO:0048185	activin binding	3/4208	11/18639	0.272727272727273	1.20802367784307	0.467641377277451	0.722381470675473
GO:0070697	activin receptor binding	3/4208	11/18639	0.272727272727273	1.20802367784307	0.467641377277451	0.722381470675473
GO:0140031	phosphorylation-dependent protein binding	3/4208	11/18639	0.272727272727273	1.20802367784307	0.467641377277451	0.722381470675473
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	3/4208	11/18639	0.272727272727273	1.20802367784307	0.467641377277451	0.722381470675473
GO:0180030	inositol phosphate kinase activity	3/4208	11/18639	0.272727272727273	1.20802367784307	0.467641377277451	0.722381470675473
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	8/4208	33/18639	0.242424242424242	1.0737988247494	0.476338534052251	0.734153401635333
GO:0030296	protein tyrosine kinase activator activity	8/4208	33/18639	0.242424242424242	1.0737988247494	0.476338534052251	0.734153401635333
GO:0003823	antigen binding	40/4208	174/18639	0.229885057471264	1.01825750622787	0.477703212225103	0.73542571272578
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	5/4208	20/18639	0.25	1.10735503802281	0.483161546829939	0.7421535471577
GO:0031418	L-ascorbic acid binding	5/4208	20/18639	0.25	1.10735503802281	0.483161546829939	0.7421535471577
GO:0042056	chemoattractant activity	10/4208	42/18639	0.238095238095238	1.05462384573601	0.483750188393246	0.742221886353642
GO:0005010	insulin-like growth factor receptor activity	12/4208	51/18639	0.235294117647059	1.04221650637441	0.489541774460002	0.74774353904081
GO:0005021	vascular endothelial growth factor receptor activity	12/4208	51/18639	0.235294117647059	1.04221650637441	0.489541774460002	0.74774353904081
GO:0005030	neurotrophin receptor activity	12/4208	51/18639	0.235294117647059	1.04221650637441	0.489541774460002	0.74774353904081
GO:0016830	carbon-carbon lyase activity	12/4208	51/18639	0.235294117647059	1.04221650637441	0.489541774460002	0.74774353904081
GO:0004181	metallocarboxypeptidase activity	7/4208	29/18639	0.241379310344828	1.06917038153927	0.491811439811912	0.749531624473126
GO:0016417	S-acyltransferase activity	7/4208	29/18639	0.241379310344828	1.06917038153927	0.491811439811912	0.749531624473126
GO:0004714	transmembrane receptor protein tyrosine kinase activity	14/4208	60/18639	0.233333333333333	1.03353136882129	0.494312502096541	0.752502514352324
GO:0000146	microfilament motor activity	9/4208	38/18639	0.236842105263158	1.04907319391635	0.497865195577992	0.757065916129745
GO:0019199	transmembrane receptor protein kinase activity	18/4208	78/18639	0.230769230769231	1.02217388125183	0.501950740271333	0.757115016397824
GO:0008509	monoatomic anion transmembrane transporter activity	34/4208	149/18639	0.228187919463087	1.01074016893358	0.503791846339662	0.757115016397824
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	4/4208	16/18639	0.25	1.10735503802281	0.504003251385062	0.757115016397824
GO:0005024	transforming growth factor beta receptor activity	4/4208	16/18639	0.25	1.10735503802281	0.504003251385062	0.757115016397824
GO:0005324	long-chain fatty acid transmembrane transporter activity	4/4208	16/18639	0.25	1.10735503802281	0.504003251385062	0.757115016397824
GO:0008142	oxysterol binding	4/4208	16/18639	0.25	1.10735503802281	0.504003251385062	0.757115016397824
GO:0015562	efflux transmembrane transporter activity	4/4208	16/18639	0.25	1.10735503802281	0.504003251385062	0.757115016397824
GO:0022841	potassium ion leak channel activity	4/4208	16/18639	0.25	1.10735503802281	0.504003251385062	0.757115016397824
GO:0031435	mitogen-activated protein kinase kinase kinase binding	4/4208	16/18639	0.25	1.10735503802281	0.504003251385062	0.757115016397824
GO:0097027	ubiquitin-protein transferase activator activity	4/4208	16/18639	0.25	1.10735503802281	0.504003251385062	0.757115016397824
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	4/4208	16/18639	0.25	1.10735503802281	0.504003251385062	0.757115016397824
GO:0003707	nuclear steroid receptor activity	6/4208	25/18639	0.24	1.0630608365019	0.509586350864671	0.759645664021215
GO:0005537	D-mannose binding	6/4208	25/18639	0.24	1.0630608365019	0.509586350864671	0.759645664021215
GO:0015645	fatty acid ligase activity	6/4208	25/18639	0.24	1.0630608365019	0.509586350864671	0.759645664021215
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	6/4208	25/18639	0.24	1.0630608365019	0.509586350864671	0.759645664021215
GO:0019706	protein-cysteine S-palmitoyltransferase activity	6/4208	25/18639	0.24	1.0630608365019	0.509586350864671	0.759645664021215
GO:0019707	protein-cysteine S-acyltransferase activity	6/4208	25/18639	0.24	1.0630608365019	0.509586350864671	0.759645664021215
GO:0120515	fatty acid-CoA ligase activity	6/4208	25/18639	0.24	1.0630608365019	0.509586350864671	0.759645664021215
GO:0016831	carboxy-lyase activity	8/4208	34/18639	0.235294117647059	1.04221650637441	0.513576134664162	0.764757475635281
GO:0008200	ion channel inhibitor activity	10/4208	43/18639	0.232558139534884	1.03009770978866	0.516794997398089	0.768711424701193
GO:0001846	opsonin binding	5/4208	21/18639	0.238095238095238	1.05462384573601	0.530562849009539	0.772629068609282
GO:0008373	sialyltransferase activity	5/4208	21/18639	0.238095238095238	1.05462384573601	0.530562849009539	0.772629068609282
GO:0061891	calcium ion sensor activity	5/4208	21/18639	0.238095238095238	1.05462384573601	0.530562849009539	0.772629068609282
GO:0000340	RNA 7-methylguanosine cap binding	3/4208	12/18639	0.25	1.10735503802281	0.530930818508779	0.772629068609282
GO:0004126	cytidine deaminase activity	3/4208	12/18639	0.25	1.10735503802281	0.530930818508779	0.772629068609282
GO:0004859	phospholipase inhibitor activity	3/4208	12/18639	0.25	1.10735503802281	0.530930818508779	0.772629068609282
GO:0005025	transforming growth factor beta receptor activity, type I	3/4208	12/18639	0.25	1.10735503802281	0.530930818508779	0.772629068609282
GO:0005026	transforming growth factor beta receptor activity, type II	3/4208	12/18639	0.25	1.10735503802281	0.530930818508779	0.772629068609282
GO:0005165	neurotrophin receptor binding	3/4208	12/18639	0.25	1.10735503802281	0.530930818508779	0.772629068609282
GO:0015166	polyol transmembrane transporter activity	3/4208	12/18639	0.25	1.10735503802281	0.530930818508779	0.772629068609282
GO:0016208	AMP binding	3/4208	12/18639	0.25	1.10735503802281	0.530930818508779	0.772629068609282
GO:0016361	activin receptor activity, type I	3/4208	12/18639	0.25	1.10735503802281	0.530930818508779	0.772629068609282
GO:0016362	activin receptor activity, type II	3/4208	12/18639	0.25	1.10735503802281	0.530930818508779	0.772629068609282
GO:0017002	activin receptor activity	3/4208	12/18639	0.25	1.10735503802281	0.530930818508779	0.772629068609282
GO:0031543	peptidyl-proline dioxygenase activity	3/4208	12/18639	0.25	1.10735503802281	0.530930818508779	0.772629068609282
GO:0070679	inositol 1,4,5 trisphosphate binding	3/4208	12/18639	0.25	1.10735503802281	0.530930818508779	0.772629068609282
GO:0140829	bicarbonate:monoatomic anion antiporter activity	3/4208	12/18639	0.25	1.10735503802281	0.530930818508779	0.772629068609282
GO:0140900	chloride:bicarbonate antiporter activity	3/4208	12/18639	0.25	1.10735503802281	0.530930818508779	0.772629068609282
GO:0141221	histone deacetylase activity, hydrolytic mechanism	3/4208	12/18639	0.25	1.10735503802281	0.530930818508779	0.772629068609282
GO:0008106	alcohol dehydrogenase (NADP+) activity	7/4208	30/18639	0.233333333333333	1.03353136882129	0.531324095568553	0.772629068609282
GO:0033612	receptor serine/threonine kinase binding	7/4208	30/18639	0.233333333333333	1.03353136882129	0.531324095568553	0.772629068609282
GO:0000217	DNA secondary structure binding	9/4208	39/18639	0.230769230769231	1.02217388125183	0.532450527361434	0.77344251258892
GO:0016829	lyase activity	45/4208	200/18639	0.225	0.996619534220532	0.538173236987965	0.780923718352749
GO:0015079	potassium ion transmembrane transporter activity	36/4208	160/18639	0.225	0.996619534220532	0.540286333974086	0.782704685946715
GO:0016757	glycosyltransferase activity	60/4208	267/18639	0.224719101123595	0.995375315076686	0.540548250851763	0.782704685946715
GO:0005003	ephrin receptor activity	12/4208	53/18639	0.226415094339623	1.00288758160557	0.549018170773073	0.790965208910579
GO:0005005	transmembrane-ephrin receptor activity	12/4208	53/18639	0.226415094339623	1.00288758160557	0.549018170773073	0.790965208910579
GO:0005246	calcium channel regulator activity	12/4208	53/18639	0.226415094339623	1.00288758160557	0.549018170773073	0.790965208910579
GO:0008146	sulfotransferase activity	12/4208	53/18639	0.226415094339623	1.00288758160557	0.549018170773073	0.790965208910579
GO:0019205	nucleobase-containing compound kinase activity	10/4208	44/18639	0.227272727272727	1.00668639820256	0.549152531406392	0.790965208910579
GO:0048306	calcium-dependent protein binding	18/4208	80/18639	0.225	0.996619534220532	0.550203277057654	0.791642689774937
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	6/4208	26/18639	0.230769230769231	1.02217388125183	0.551760046209044	0.792211266346459
GO:0030507	spectrin binding	6/4208	26/18639	0.230769230769231	1.02217388125183	0.551760046209044	0.792211266346459
GO:0004029	aldehyde dehydrogenase (NAD+) activity	4/4208	17/18639	0.235294117647059	1.04221650637441	0.556286488430299	0.792868098452381
GO:0015347	sodium-independent organic anion transmembrane transporter activity	4/4208	17/18639	0.235294117647059	1.04221650637441	0.556286488430299	0.792868098452381
GO:0016018	cyclosporin A binding	4/4208	17/18639	0.235294117647059	1.04221650637441	0.556286488430299	0.792868098452381
GO:0016805	dipeptidase activity	4/4208	17/18639	0.235294117647059	1.04221650637441	0.556286488430299	0.792868098452381
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	4/4208	17/18639	0.235294117647059	1.04221650637441	0.556286488430299	0.792868098452381
GO:0031489	myosin V binding	4/4208	17/18639	0.235294117647059	1.04221650637441	0.556286488430299	0.792868098452381
GO:0070403	NAD+ binding	4/4208	17/18639	0.235294117647059	1.04221650637441	0.556286488430299	0.792868098452381
GO:0141108	transporter regulator activity	38/4208	170/18639	0.223529411764706	0.990105681055692	0.557975180030841	0.794133021297798
GO:0098631	cell adhesion mediator activity	17/4208	76/18639	0.223684210526316	0.990791349809886	0.562088595273083	0.794133021297798
GO:0005004	GPI-linked ephrin receptor activity	11/4208	49/18639	0.224489795918367	0.994359625979669	0.564160482138978	0.794133021297798
GO:0005008	hepatocyte growth factor receptor activity	11/4208	49/18639	0.224489795918367	0.994359625979669	0.564160482138978	0.794133021297798
GO:0005009	insulin receptor activity	11/4208	49/18639	0.224489795918367	0.994359625979669	0.564160482138978	0.794133021297798
GO:0005011	macrophage colony-stimulating factor receptor activity	11/4208	49/18639	0.224489795918367	0.994359625979669	0.564160482138978	0.794133021297798
GO:0005018	platelet-derived growth factor alpha-receptor activity	11/4208	49/18639	0.224489795918367	0.994359625979669	0.564160482138978	0.794133021297798
GO:0005020	stem cell factor receptor activity	11/4208	49/18639	0.224489795918367	0.994359625979669	0.564160482138978	0.794133021297798
GO:0008288	boss receptor activity	11/4208	49/18639	0.224489795918367	0.994359625979669	0.564160482138978	0.794133021297798
GO:0036332	placental growth factor receptor activity	11/4208	49/18639	0.224489795918367	0.994359625979669	0.564160482138978	0.794133021297798
GO:0038062	protein tyrosine kinase collagen receptor activity	11/4208	49/18639	0.224489795918367	0.994359625979669	0.564160482138978	0.794133021297798
GO:0060175	brain-derived neurotrophic factor receptor activity	11/4208	49/18639	0.224489795918367	0.994359625979669	0.564160482138978	0.794133021297798
GO:0005310	dicarboxylic acid transmembrane transporter activity	7/4208	31/18639	0.225806451612903	1.00019164724641	0.569564889280043	0.800089092665272
GO:0016878	acid-thiol ligase activity	7/4208	31/18639	0.225806451612903	1.00019164724641	0.569564889280043	0.800089092665272
GO:0008083	growth factor activity	36/4208	162/18639	0.222222222222222	0.984315589353612	0.57384045208509	0.803196213905565
GO:0004407	histone deacetylase activity	5/4208	22/18639	0.227272727272727	1.00668639820256	0.575898751612641	0.803196213905565
GO:0033558	protein lysine deacetylase activity	5/4208	22/18639	0.227272727272727	1.00668639820256	0.575898751612641	0.803196213905565
GO:0034062	5'-3' RNA polymerase activity	5/4208	22/18639	0.227272727272727	1.00668639820256	0.575898751612641	0.803196213905565
GO:0097747	RNA polymerase activity	5/4208	22/18639	0.227272727272727	1.00668639820256	0.575898751612641	0.803196213905565
GO:0140035	ubiquitin-like protein reader activity	5/4208	22/18639	0.227272727272727	1.00668639820256	0.575898751612641	0.803196213905565
GO:0140784	metal ion sensor activity	5/4208	22/18639	0.227272727272727	1.00668639820256	0.575898751612641	0.803196213905565
GO:0051539	4 iron, 4 sulfur cluster binding	10/4208	45/18639	0.222222222222222	0.984315589353612	0.580647114978275	0.808991486037147
GO:0004033	aldo-keto reductase (NADPH) activity	8/4208	36/18639	0.222222222222222	0.984315589353612	0.585019510224669	0.813421622779254
GO:0055106	ubiquitin-protein transferase regulator activity	8/4208	36/18639	0.222222222222222	0.984315589353612	0.585019510224669	0.813421622779254
GO:0039706	co-receptor binding	3/4208	13/18639	0.230769230769231	1.02217388125183	0.589733222853325	0.818097752987007
GO:0070700	BMP receptor binding	3/4208	13/18639	0.230769230769231	1.02217388125183	0.589733222853325	0.818097752987007
GO:0070888	E-box binding	13/4208	59/18639	0.220338983050847	0.975973931816717	0.590339604631669	0.818097752987007
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	6/4208	27/18639	0.222222222222222	0.984315589353612	0.592187226428199	0.818097752987007
GO:0035255	ionotropic glutamate receptor binding	6/4208	27/18639	0.222222222222222	0.984315589353612	0.592187226428199	0.818097752987007
GO:0005006	epidermal growth factor receptor activity	11/4208	50/18639	0.22	0.974472433460076	0.593780627167989	0.818097752987007
GO:0005007	fibroblast growth factor receptor activity	11/4208	50/18639	0.22	0.974472433460076	0.593780627167989	0.818097752987007
GO:0005017	platelet-derived growth factor receptor activity	11/4208	50/18639	0.22	0.974472433460076	0.593780627167989	0.818097752987007
GO:0005019	platelet-derived growth factor beta-receptor activity	11/4208	50/18639	0.22	0.974472433460076	0.593780627167989	0.818097752987007
GO:0016247	channel regulator activity	37/4208	168/18639	0.220238095238095	0.975527057305812	0.598329806387844	0.822864753684211
GO:0016877	ligase activity, forming carbon-sulfur bonds	9/4208	41/18639	0.219512195121951	0.972311740702958	0.598741469373307	0.822864753684211
GO:0019842	vitamin binding	33/4208	150/18639	0.22	0.974472433460076	0.599050366868344	0.822864753684211
GO:0004536	DNA nuclease activity	14/4208	64/18639	0.21875	0.968935658269962	0.601934992185933	0.825312711591598
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	4/4208	18/18639	0.222222222222222	0.984315589353612	0.605440849244735	0.825312711591598
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	4/4208	18/18639	0.222222222222222	0.984315589353612	0.605440849244735	0.825312711591598
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	4/4208	18/18639	0.222222222222222	0.984315589353612	0.605440849244735	0.825312711591598
GO:0031690	adrenergic receptor binding	4/4208	18/18639	0.222222222222222	0.984315589353612	0.605440849244735	0.825312711591598
GO:0099602	neurotransmitter receptor regulator activity	4/4208	18/18639	0.222222222222222	0.984315589353612	0.605440849244735	0.825312711591598
GO:1901611	phosphatidylglycerol binding	4/4208	18/18639	0.222222222222222	0.984315589353612	0.605440849244735	0.825312711591598
GO:0015106	bicarbonate transmembrane transporter activity	7/4208	32/18639	0.21875	0.968935658269962	0.606278106315822	0.825312711591598
GO:0140142	nucleocytoplasmic carrier activity	7/4208	32/18639	0.21875	0.968935658269962	0.606278106315822	0.825312711591598
GO:0099106	ion channel regulator activity	35/4208	160/18639	0.21875	0.968935658269962	0.614979404286893	0.836322938631428
GO:0070001	aspartic-type peptidase activity	8/4208	37/18639	0.216216216216216	0.957712465317028	0.618790337777955	0.839008787701054
GO:0003887	DNA-directed DNA polymerase activity	5/4208	23/18639	0.217391304347826	0.962917424367664	0.618799736383622	0.839008787701054
GO:0017134	fibroblast growth factor binding	5/4208	23/18639	0.217391304347826	0.962917424367664	0.618799736383622	0.839008787701054
GO:0016835	carbon-oxygen lyase activity	17/4208	79/18639	0.215189873417722	0.953166361842422	0.632360578694583	0.856544021191074
GO:0022832	voltage-gated channel activity	38/4208	175/18639	0.217142857142857	0.961816947311244	0.637007218678333	0.861981990354411
GO:0008559	ABC-type xenobiotic transporter activity	3/4208	14/18639	0.214285714285714	0.949161461162412	0.643538085799965	0.863962548259008
GO:0016530	metallochaperone activity	3/4208	14/18639	0.214285714285714	0.949161461162412	0.643538085799965	0.863962548259008
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	3/4208	14/18639	0.214285714285714	0.949161461162412	0.643538085799965	0.863962548259008
GO:0032036	myosin heavy chain binding	3/4208	14/18639	0.214285714285714	0.949161461162412	0.643538085799965	0.863962548259008
GO:0042043	neurexin family protein binding	3/4208	14/18639	0.214285714285714	0.949161461162412	0.643538085799965	0.863962548259008
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	3/4208	14/18639	0.214285714285714	0.949161461162412	0.643538085799965	0.863962548259008
GO:0098821	BMP receptor activity	3/4208	14/18639	0.214285714285714	0.949161461162412	0.643538085799965	0.863962548259008
GO:1990825	sequence-specific mRNA binding	3/4208	14/18639	0.214285714285714	0.949161461162412	0.643538085799965	0.863962548259008
GO:0008574	plus-end-directed microtubule motor activity	4/4208	19/18639	0.210526315789474	0.932509505703422	0.651109186274652	0.872336489114873
GO:0034987	immunoglobulin receptor binding	4/4208	19/18639	0.210526315789474	0.932509505703422	0.651109186274652	0.872336489114873
GO:0008235	metalloexopeptidase activity	14/4208	66/18639	0.212121212121212	0.939573971655721	0.651694195313824	0.872336489114873
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	39/4208	181/18639	0.215469613259669	0.954405447135685	0.658635021978904	0.880762911744338
GO:0099604	ligand-gated calcium channel activity	6/4208	29/18639	0.206896551724138	0.916431755605087	0.666806804788375	0.887657637491263
GO:0016879	ligase activity, forming carbon-nitrogen bonds	10/4208	48/18639	0.208333333333333	0.922795865019011	0.668558598576753	0.887657637491263
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	7/4208	34/18639	0.205882352941176	0.911939443077611	0.674365537995783	0.887657637491263
GO:0005244	voltage-gated monoatomic ion channel activity	37/4208	173/18639	0.213872832369942	0.947332633684257	0.675103589887574	0.887657637491263
GO:0008173	RNA methyltransferase activity	14/4208	67/18639	0.208955223880597	0.925550479541456	0.675287105137036	0.887657637491263
GO:0046982	protein heterodimerization activity	80/4208	369/18639	0.21680216802168	0.960307892052305	0.680859599004341	0.887657637491263
GO:0016776	phosphotransferase activity, phosphate group as acceptor	8/4208	39/18639	0.205128205128205	0.90859900555718	0.681640013978335	0.887657637491263
GO:0015103	inorganic anion transmembrane transporter activity	35/4208	165/18639	0.212121212121212	0.939573971655721	0.692115144648714	0.887657637491263
GO:0004089	carbonate dehydratase activity	3/4208	15/18639	0.2	0.885884030418251	0.692138200930468	0.887657637491263
GO:0004865	protein serine/threonine phosphatase inhibitor activity	3/4208	15/18639	0.2	0.885884030418251	0.692138200930468	0.887657637491263
GO:0016846	carbon-sulfur lyase activity	3/4208	15/18639	0.2	0.885884030418251	0.692138200930468	0.887657637491263
GO:0031005	filamin binding	3/4208	15/18639	0.2	0.885884030418251	0.692138200930468	0.887657637491263
GO:0031386	protein tag activity	3/4208	15/18639	0.2	0.885884030418251	0.692138200930468	0.887657637491263
GO:0033130	acetylcholine receptor binding	3/4208	15/18639	0.2	0.885884030418251	0.692138200930468	0.887657637491263
GO:0050780	dopamine receptor binding	3/4208	15/18639	0.2	0.885884030418251	0.692138200930468	0.887657637491263
GO:0141047	molecular tag activity	3/4208	15/18639	0.2	0.885884030418251	0.692138200930468	0.887657637491263
GO:0001972	retinoic acid binding	4/4208	20/18639	0.2	0.885884030418251	0.693096096135829	0.887657637491263
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	4/4208	20/18639	0.2	0.885884030418251	0.693096096135829	0.887657637491263
GO:0005326	neurotransmitter transmembrane transporter activity	4/4208	20/18639	0.2	0.885884030418251	0.693096096135829	0.887657637491263
GO:0010851	cyclase regulator activity	4/4208	20/18639	0.2	0.885884030418251	0.693096096135829	0.887657637491263
GO:0008483	transaminase activity	5/4208	25/18639	0.2	0.885884030418251	0.69636274038172	0.887657637491263
GO:0017056	structural constituent of nuclear pore	5/4208	25/18639	0.2	0.885884030418251	0.69636274038172	0.887657637491263
GO:0000182	rDNA binding	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0004090	carbonyl reductase (NADPH) activity	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0005131	growth hormone receptor binding	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0005522	profilin binding	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0008190	eukaryotic initiation factor 4E binding	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0008519	ammonium channel activity	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0008641	ubiquitin-like modifier activating enzyme activity	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0016303	1-phosphatidylinositol-3-kinase activity	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0016868	intramolecular phosphotransferase activity	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0031956	medium-chain fatty acid-CoA ligase activity	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0031957	very long-chain fatty acid-CoA ligase activity	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0032052	bile acid binding	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0043208	glycosphingolipid binding	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0050815	phosphoserine residue binding	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0070097	delta-catenin binding	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0070739	protein-glutamic acid ligase activity	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0070740	tubulin-glutamic acid ligase activity	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0098505	G-rich strand telomeric DNA binding	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0140135	mechanosensitive monoatomic cation channel activity	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:1990757	ubiquitin ligase activator activity	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:1990763	arrestin family protein binding	2/4208	10/18639	0.2	0.885884030418251	0.696980447033096	0.887657637491263
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	6/4208	30/18639	0.2	0.885884030418251	0.700677482093331	0.891533661917261
GO:0017069	snRNA binding	11/4208	54/18639	0.203703703703704	0.902289290240811	0.701764098282302	0.89208409138589
GO:0004521	RNA endonuclease activity	15/4208	73/18639	0.205479452054795	0.910154825772176	0.704431160611223	0.894640691874961
GO:0022843	voltage-gated monoatomic cation channel activity	30/4208	143/18639	0.20979020979021	0.929248982956207	0.707548538950448	0.897763913607824
GO:0005261	monoatomic cation channel activity	73/4208	341/18639	0.214076246334311	0.948233639597248	0.718591632671455	0.910928426546343
GO:0031491	nucleosome binding	15/4208	74/18639	0.202702702702703	0.897855436234714	0.725172903765173	0.918417679420331
GO:0009975	cyclase activity	4/4208	21/18639	0.19047619047619	0.84369907658881	0.731339213106721	0.924510367634446
GO:0140312	cargo adaptor activity	4/4208	21/18639	0.19047619047619	0.84369907658881	0.731339213106721	0.924510367634446
GO:0004190	aspartic-type endopeptidase activity	7/4208	36/18639	0.194444444444444	0.861276140684411	0.734564548304597	0.92554944595791
GO:0003688	DNA replication origin binding	3/4208	16/18639	0.1875	0.83051627851711	0.73555395851787	0.92554944595791
GO:0008296	3'-5'-DNA exonuclease activity	3/4208	16/18639	0.1875	0.83051627851711	0.73555395851787	0.92554944595791
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	3/4208	16/18639	0.1875	0.83051627851711	0.73555395851787	0.92554944595791
GO:0043023	ribosomal large subunit binding	3/4208	16/18639	0.1875	0.83051627851711	0.73555395851787	0.92554944595791
GO:0017080	sodium channel regulator activity	8/4208	41/18639	0.195121951219512	0.864277102847074	0.737612108572474	0.926609037246108
GO:0016782	transferase activity, transferring sulphur-containing groups	14/4208	70/18639	0.2	0.885884030418251	0.740330814473274	0.926609037246108
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	25/4208	122/18639	0.204918032786885	0.907668063953126	0.742077122035554	0.926609037246108
GO:0004519	endonuclease activity	26/4208	127/18639	0.204724409448819	0.90681042483758	0.746899414509123	0.926609037246108
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	2/4208	11/18639	0.181818181818182	0.805349118562046	0.747944684756573	0.926609037246108
GO:0004143	ATP-dependent diacylglycerol kinase activity	2/4208	11/18639	0.181818181818182	0.805349118562046	0.747944684756573	0.926609037246108
GO:0008271	secondary active sulfate transmembrane transporter activity	2/4208	11/18639	0.181818181818182	0.805349118562046	0.747944684756573	0.926609037246108
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/4208	11/18639	0.181818181818182	0.805349118562046	0.747944684756573	0.926609037246108
GO:0019206	nucleoside kinase activity	2/4208	11/18639	0.181818181818182	0.805349118562046	0.747944684756573	0.926609037246108
GO:0019864	IgG binding	2/4208	11/18639	0.181818181818182	0.805349118562046	0.747944684756573	0.926609037246108
GO:0031731	CCR6 chemokine receptor binding	2/4208	11/18639	0.181818181818182	0.805349118562046	0.747944684756573	0.926609037246108
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	2/4208	11/18639	0.181818181818182	0.805349118562046	0.747944684756573	0.926609037246108
GO:0034511	U3 snoRNA binding	2/4208	11/18639	0.181818181818182	0.805349118562046	0.747944684756573	0.926609037246108
GO:0035252	UDP-xylosyltransferase activity	2/4208	11/18639	0.181818181818182	0.805349118562046	0.747944684756573	0.926609037246108
GO:0042285	xylosyltransferase activity	2/4208	11/18639	0.181818181818182	0.805349118562046	0.747944684756573	0.926609037246108
GO:0048407	platelet-derived growth factor binding	2/4208	11/18639	0.181818181818182	0.805349118562046	0.747944684756573	0.926609037246108
GO:0050998	nitric-oxide synthase binding	2/4208	11/18639	0.181818181818182	0.805349118562046	0.747944684756573	0.926609037246108
GO:0000049	tRNA binding	16/4208	80/18639	0.2	0.885884030418251	0.74951163467287	0.927707685747544
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	12/4208	61/18639	0.19672131147541	0.871361341395001	0.752291460762867	0.929461551159919
GO:0016836	hydro-lyase activity	12/4208	61/18639	0.19672131147541	0.871361341395001	0.752291460762867	0.929461551159919
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	6/4208	32/18639	0.1875	0.83051627851711	0.761190596226835	0.939176085949822
GO:0022829	wide pore channel activity	7/4208	37/18639	0.189189189189189	0.8379984071524	0.761578530760813	0.939176085949822
GO:0005044	scavenger receptor activity	5/4208	27/18639	0.185185185185185	0.82026299112801	0.762293027564471	0.939176085949822
GO:0031492	nucleosomal DNA binding	8/4208	42/18639	0.19047619047619	0.84369907658881	0.762908433454841	0.939176085949822
GO:0140938	histone H3 methyltransferase activity	9/4208	47/18639	0.191489361702128	0.848186837634496	0.764854610657739	0.940722893541168
GO:0005243	gap junction channel activity	4/4208	22/18639	0.181818181818182	0.805349118562046	0.765881537883183	0.941137313218615
GO:0005267	potassium channel activity	25/4208	124/18639	0.201612903225806	0.893028256470011	0.771718010510477	0.945961397814617
GO:0009881	photoreceptor activity	3/4208	17/18639	0.176470588235294	0.78166237978081	0.773968416393777	0.945961397814617
GO:0015278	intracellularly gated calcium channel activity	3/4208	17/18639	0.176470588235294	0.78166237978081	0.773968416393777	0.945961397814617
GO:0017110	nucleoside diphosphate phosphatase activity	3/4208	17/18639	0.176470588235294	0.78166237978081	0.773968416393777	0.945961397814617
GO:0030548	acetylcholine receptor regulator activity	3/4208	17/18639	0.176470588235294	0.78166237978081	0.773968416393777	0.945961397814617
GO:0070492	oligosaccharide binding	3/4208	17/18639	0.176470588235294	0.78166237978081	0.773968416393777	0.945961397814617
GO:0016500	protein-hormone receptor activity	13/4208	67/18639	0.194029850746269	0.859439731002781	0.775616701430488	0.947127288049405
GO:0005109	frizzled binding	7/4208	38/18639	0.184210526315789	0.815945817490494	0.786539512011569	0.952690143619032
GO:0005501	retinoid binding	7/4208	38/18639	0.184210526315789	0.815945817490494	0.786539512011569	0.952690143619032
GO:0019840	isoprenoid binding	7/4208	38/18639	0.184210526315789	0.815945817490494	0.786539512011569	0.952690143619032
GO:0004032	aldose reductase (NADPH) activity	2/4208	12/18639	0.166666666666667	0.738236692015209	0.791347458006131	0.952690143619032
GO:0005436	sodium:phosphate symporter activity	2/4208	12/18639	0.166666666666667	0.738236692015209	0.791347458006131	0.952690143619032
GO:0008504	monoamine transmembrane transporter activity	2/4208	12/18639	0.166666666666667	0.738236692015209	0.791347458006131	0.952690143619032
GO:0010853	cyclase activator activity	2/4208	12/18639	0.166666666666667	0.738236692015209	0.791347458006131	0.952690143619032
GO:0016273	arginine N-methyltransferase activity	2/4208	12/18639	0.166666666666667	0.738236692015209	0.791347458006131	0.952690143619032
GO:0016274	protein-arginine N-methyltransferase activity	2/4208	12/18639	0.166666666666667	0.738236692015209	0.791347458006131	0.952690143619032
GO:0016801	hydrolase activity, acting on ether bonds	2/4208	12/18639	0.166666666666667	0.738236692015209	0.791347458006131	0.952690143619032
GO:0016803	ether hydrolase activity	2/4208	12/18639	0.166666666666667	0.738236692015209	0.791347458006131	0.952690143619032
GO:0043047	single-stranded telomeric DNA binding	2/4208	12/18639	0.166666666666667	0.738236692015209	0.791347458006131	0.952690143619032
GO:0097371	MDM2/MDM4 family protein binding	2/4208	12/18639	0.166666666666667	0.738236692015209	0.791347458006131	0.952690143619032
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	2/4208	12/18639	0.166666666666667	0.738236692015209	0.791347458006131	0.952690143619032
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	2/4208	12/18639	0.166666666666667	0.738236692015209	0.791347458006131	0.952690143619032
GO:1990459	transferrin receptor binding	2/4208	12/18639	0.166666666666667	0.738236692015209	0.791347458006131	0.952690143619032
GO:0005201	extracellular matrix structural constituent	34/4208	168/18639	0.202380952380952	0.896430268875611	0.792580465528367	0.953333117266924
GO:0004022	alcohol dehydrogenase (NAD+) activity	4/4208	23/18639	0.173913043478261	0.770333939494131	0.796846127672565	0.955935020356533
GO:0008171	O-methyltransferase activity	4/4208	23/18639	0.173913043478261	0.770333939494131	0.796846127672565	0.955935020356533
GO:0099186	structural constituent of postsynapse	4/4208	23/18639	0.173913043478261	0.770333939494131	0.796846127672565	0.955935020356533
GO:0016758	hexosyltransferase activity	40/4208	197/18639	0.203045685279188	0.899374650170813	0.801839503081384	0.961080037085244
GO:0099094	ligand-gated monoatomic cation channel activity	27/4208	136/18639	0.198529411764706	0.879370177253411	0.805313305996161	0.963549446385693
GO:0000900	mRNA regulatory element binding translation repressor activity	3/4208	18/18639	0.166666666666667	0.738236692015209	0.807673929823586	0.963549446385693
GO:0015280	ligand-gated sodium channel activity	3/4208	18/18639	0.166666666666667	0.738236692015209	0.807673929823586	0.963549446385693
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	3/4208	18/18639	0.166666666666667	0.738236692015209	0.807673929823586	0.963549446385693
GO:0035615	clathrin adaptor activity	3/4208	18/18639	0.166666666666667	0.738236692015209	0.807673929823586	0.963549446385693
GO:0030547	signaling receptor inhibitor activity	8/4208	44/18639	0.181818181818182	0.805349118562046	0.808138245355743	0.963549446385693
GO:0003785	actin monomer binding	5/4208	29/18639	0.172413793103448	0.763693129670906	0.816779040012078	0.972152365249978
GO:0106222	lncRNA binding	5/4208	29/18639	0.172413793103448	0.763693129670906	0.816779040012078	0.972152365249978
GO:0016853	isomerase activity	36/4208	180/18639	0.2	0.885884030418251	0.820701913842252	0.975969843488083
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	11/4208	60/18639	0.183333333333333	0.81206036121673	0.82623260280857	0.979530150076547
GO:0016278	lysine N-methyltransferase activity	13/4208	70/18639	0.185714285714286	0.82260659967409	0.827400676745569	0.979530150076547
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	2/4208	13/18639	0.153846153846154	0.681449254167885	0.828004591670278	0.979530150076547
GO:0004993	G protein-coupled serotonin receptor activity	2/4208	13/18639	0.153846153846154	0.681449254167885	0.828004591670278	0.979530150076547
GO:0005542	folic acid binding	2/4208	13/18639	0.153846153846154	0.681449254167885	0.828004591670278	0.979530150076547
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	2/4208	13/18639	0.153846153846154	0.681449254167885	0.828004591670278	0.979530150076547
GO:0004177	aminopeptidase activity	7/4208	40/18639	0.175	0.77514852661597	0.830480099965446	0.980757451387764
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	7/4208	40/18639	0.175	0.77514852661597	0.830480099965446	0.980757451387764
GO:0034061	DNA polymerase activity	6/4208	35/18639	0.171428571428571	0.759329168929929	0.834227628511045	0.981692754464326
GO:0003756	protein disulfide isomerase activity	3/4208	19/18639	0.157894736842105	0.699382129277566	0.837029819239011	0.981692754464326
GO:0005229	intracellularly calcium-gated chloride channel activity	3/4208	19/18639	0.157894736842105	0.699382129277566	0.837029819239011	0.981692754464326
GO:0008381	mechanosensitive monoatomic ion channel activity	3/4208	19/18639	0.157894736842105	0.699382129277566	0.837029819239011	0.981692754464326
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	3/4208	19/18639	0.157894736842105	0.699382129277566	0.837029819239011	0.981692754464326
GO:0016918	retinal binding	3/4208	19/18639	0.157894736842105	0.699382129277566	0.837029819239011	0.981692754464326
GO:0070003	threonine-type peptidase activity	3/4208	19/18639	0.157894736842105	0.699382129277566	0.837029819239011	0.981692754464326
GO:0141147	intracellularly calcium-gated channel activity	3/4208	19/18639	0.157894736842105	0.699382129277566	0.837029819239011	0.981692754464326
GO:0016769	transferase activity, transferring nitrogenous groups	5/4208	30/18639	0.166666666666667	0.738236692015209	0.839999351595827	0.983484219379149
GO:0048019	receptor antagonist activity	5/4208	30/18639	0.166666666666667	0.738236692015209	0.839999351595827	0.983484219379149
GO:0140299	molecular sensor activity	13/4208	71/18639	0.183098591549296	0.811020591227976	0.842507471908368	0.985574778458846
GO:0001848	complement binding	4/4208	25/18639	0.16	0.708707224334601	0.848804550298024	0.990392991109072
GO:0005251	delayed rectifier potassium channel activity	4/4208	25/18639	0.16	0.708707224334601	0.848804550298024	0.990392991109072
GO:0015271	outward rectifier potassium channel activity	4/4208	25/18639	0.16	0.708707224334601	0.848804550298024	0.990392991109072
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	6/4208	36/18639	0.166666666666667	0.738236692015209	0.854160244552335	0.994340958154593
GO:0017171	serine hydrolase activity	39/4208	198/18639	0.196969696969697	0.872461545108883	0.855905472744552	0.994340958154593
GO:0008174	mRNA methyltransferase activity	2/4208	14/18639	0.142857142857143	0.632774307441608	0.85874900931533	0.994340958154593
GO:0015926	glucosidase activity	2/4208	14/18639	0.142857142857143	0.632774307441608	0.85874900931533	0.994340958154593
GO:0019763	immunoglobulin receptor activity	2/4208	14/18639	0.142857142857143	0.632774307441608	0.85874900931533	0.994340958154593
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	2/4208	14/18639	0.142857142857143	0.632774307441608	0.85874900931533	0.994340958154593
GO:0030983	mismatched DNA binding	2/4208	14/18639	0.142857142857143	0.632774307441608	0.85874900931533	0.994340958154593
GO:0031404	chloride ion binding	2/4208	14/18639	0.142857142857143	0.632774307441608	0.85874900931533	0.994340958154593
GO:1901612	cardiolipin binding	2/4208	14/18639	0.142857142857143	0.632774307441608	0.85874900931533	0.994340958154593
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	9/4208	52/18639	0.173076923076923	0.766630410938871	0.86058001112804	0.994957857336527
GO:0047499	calcium-independent phospholipase A2 activity	5/4208	31/18639	0.161290322580645	0.714422605176009	0.86074066837031	0.994957857336527
GO:0016408	C-acyltransferase activity	3/4208	20/18639	0.15	0.664413022813688	0.862429888021926	0.996066356699328
GO:0004520	DNA endonuclease activity	7/4208	42/18639	0.166666666666667	0.738236692015209	0.866938289964654	1
GO:0015399	primary active transmembrane transporter activity	32/4208	166/18639	0.192771084337349	0.853864125704338	0.868510651485122	1
GO:0070006	metalloaminopeptidase activity	4/4208	26/18639	0.153846153846154	0.681449254167885	0.870261386119487	1
GO:0005253	monoatomic anion channel activity	19/4208	103/18639	0.184466019417476	0.817077503783824	0.870847840622855	1
GO:0019213	deacetylase activity	6/4208	37/18639	0.162162162162162	0.718284348987771	0.872079285931339	1
GO:0016251	RNA polymerase II general transcription initiation factor activity	9/4208	53/18639	0.169811320754717	0.752165686204175	0.875363488597906	1
GO:0047498	calcium-dependent phospholipase A2 activity	5/4208	32/18639	0.15625	0.692096898764259	0.879175866915398	1
GO:0016279	protein-lysine N-methyltransferase activity	12/4208	69/18639	0.173913043478261	0.770333939494131	0.882793733411528	1
GO:0015125	bile acid transmembrane transporter activity	3/4208	21/18639	0.142857142857143	0.632774307441608	0.884278333841126	1
GO:0036122	BMP binding	3/4208	21/18639	0.142857142857143	0.632774307441608	0.884278333841126	1
GO:0008242	omega peptidase activity	2/4208	15/18639	0.133333333333333	0.590589353612167	0.88438144137454	1
GO:0010181	FMN binding	2/4208	15/18639	0.133333333333333	0.590589353612167	0.88438144137454	1
GO:0015116	sulfate transmembrane transporter activity	2/4208	15/18639	0.133333333333333	0.590589353612167	0.88438144137454	1
GO:0015250	water channel activity	2/4208	15/18639	0.133333333333333	0.590589353612167	0.88438144137454	1
GO:0045504	dynein heavy chain binding	2/4208	15/18639	0.133333333333333	0.590589353612167	0.88438144137454	1
GO:0055105	ubiquitin-protein transferase inhibitor activity	2/4208	15/18639	0.133333333333333	0.590589353612167	0.88438144137454	1
GO:0050661	NADP binding	9/4208	54/18639	0.166666666666667	0.738236692015209	0.888841451926368	1
GO:0051287	NAD binding	9/4208	54/18639	0.166666666666667	0.738236692015209	0.888841451926368	1
GO:0005216	monoatomic ion channel activity	91/4208	448/18639	0.203125	0.899725968393536	0.889250685906457	1
GO:0030020	extracellular matrix structural constituent conferring tensile strength	7/4208	44/18639	0.159090909090909	0.704680478741791	0.896683641505349	1
GO:0015108	chloride transmembrane transporter activity	22/4208	121/18639	0.181818181818182	0.805349118562046	0.900302147223869	1
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	6/4208	39/18639	0.153846153846154	0.681449254167885	0.902414669238561	1
GO:0008649	rRNA methyltransferase activity	3/4208	22/18639	0.136363636363636	0.604011838921535	0.902972564781854	1
GO:0030021	extracellular matrix structural constituent conferring compression resistance	3/4208	22/18639	0.136363636363636	0.604011838921535	0.902972564781854	1
GO:0051536	iron-sulfur cluster binding	13/4208	76/18639	0.171052631578947	0.75766397338403	0.903252848851768	1
GO:0005242	inward rectifier potassium channel activity	4/4208	28/18639	0.142857142857143	0.632774307441608	0.90539128093484	1
GO:0016866	intramolecular transferase activity	4/4208	28/18639	0.142857142857143	0.632774307441608	0.90539128093484	1
GO:0017070	U6 snRNA binding	2/4208	16/18639	0.125	0.553677519011407	0.905642510354064	1
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	2/4208	16/18639	0.125	0.553677519011407	0.905642510354064	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	24/4208	132/18639	0.181818181818182	0.805349118562046	0.908661598882591	1
GO:0052689	carboxylic ester hydrolase activity	16/4208	92/18639	0.173913043478261	0.770333939494131	0.909490605524273	1
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	31/4208	167/18639	0.18562874251497	0.822227692903167	0.912184528474854	1
GO:0051540	metal cluster binding	13/4208	77/18639	0.168831168831169	0.7478241815219	0.912726964418328	1
GO:0071855	neuropeptide receptor binding	6/4208	40/18639	0.15	0.664413022813688	0.91510900499264	1
GO:0042054	histone methyltransferase activity	11/4208	67/18639	0.164179104477612	0.72721823392543	0.916509899872426	1
GO:0005249	voltage-gated potassium channel activity	17/4208	98/18639	0.173469387755102	0.768368801893381	0.91700291657335	1
GO:0004602	glutathione peroxidase activity	3/4208	23/18639	0.130434782608696	0.577750454620598	0.918891530348248	1
GO:0005212	structural constituent of eye lens	3/4208	23/18639	0.130434782608696	0.577750454620598	0.918891530348248	1
GO:0016917	GABA receptor activity	3/4208	23/18639	0.130434782608696	0.577750454620598	0.918891530348248	1
GO:0140102	catalytic activity, acting on a rRNA	3/4208	23/18639	0.130434782608696	0.577750454620598	0.918891530348248	1
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	7/4208	46/18639	0.152173913043478	0.674042197057365	0.920586603177813	1
GO:0004601	peroxidase activity	9/4208	57/18639	0.157894736842105	0.699382129277566	0.922200358861175	1
GO:0004623	phospholipase A2 activity	5/4208	35/18639	0.142857142857143	0.632774307441608	0.922456605154431	1
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	1/4208	10/18639	0.1	0.442942015209126	0.922654985790084	1
GO:0003796	lysozyme activity	1/4208	10/18639	0.1	0.442942015209126	0.922654985790084	1
GO:0008401	retinoic acid 4-hydroxylase activity	1/4208	10/18639	0.1	0.442942015209126	0.922654985790084	1
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/4208	10/18639	0.1	0.442942015209126	0.922654985790084	1
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/4208	10/18639	0.1	0.442942015209126	0.922654985790084	1
GO:0019531	oxalate transmembrane transporter activity	1/4208	10/18639	0.1	0.442942015209126	0.922654985790084	1
GO:0032356	oxidized DNA binding	1/4208	10/18639	0.1	0.442942015209126	0.922654985790084	1
GO:0042166	acetylcholine binding	1/4208	10/18639	0.1	0.442942015209126	0.922654985790084	1
GO:0043295	glutathione binding	1/4208	10/18639	0.1	0.442942015209126	0.922654985790084	1
GO:0045322	unmethylated CpG binding	1/4208	10/18639	0.1	0.442942015209126	0.922654985790084	1
GO:0047429	nucleoside triphosphate diphosphatase activity	1/4208	10/18639	0.1	0.442942015209126	0.922654985790084	1
GO:0051378	serotonin binding	1/4208	10/18639	0.1	0.442942015209126	0.922654985790084	1
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/4208	10/18639	0.1	0.442942015209126	0.922654985790084	1
GO:0140940	histone H2A methyltransferase activity	1/4208	10/18639	0.1	0.442942015209126	0.922654985790084	1
GO:0140999	histone H3K4 trimethyltransferase activity	1/4208	10/18639	0.1	0.442942015209126	0.922654985790084	1
GO:1990259	histone H2AQ104 methyltransferase activity	1/4208	10/18639	0.1	0.442942015209126	0.922654985790084	1
GO:0005506	iron ion binding	28/4208	154/18639	0.181818181818182	0.805349118562046	0.923107471938384	1
GO:0004550	nucleoside diphosphate kinase activity	2/4208	17/18639	0.117647058823529	0.521108253187206	0.923199056215435	1
GO:0032977	membrane insertase activity	2/4208	17/18639	0.117647058823529	0.521108253187206	0.923199056215435	1
GO:0070402	NADPH binding	2/4208	17/18639	0.117647058823529	0.521108253187206	0.923199056215435	1
GO:0008236	serine-type peptidase activity	36/4208	194/18639	0.185567010309278	0.821954255027243	0.926607299424971	1
GO:0008168	methyltransferase activity	38/4208	204/18639	0.186274509803922	0.82508806754641	0.92772591768842	1
GO:0098918	structural constituent of synapse	4/4208	30/18639	0.133333333333333	0.590589353612167	0.931810760695813	1
GO:0140612	DNA damage sensor activity	3/4208	24/18639	0.125	0.553677519011407	0.932388340296367	1
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	5/4208	36/18639	0.138888888888889	0.615197243346008	0.933472147187028	1
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	5/4208	36/18639	0.138888888888889	0.615197243346008	0.933472147187028	1
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	5/4208	36/18639	0.138888888888889	0.615197243346008	0.933472147187028	1
GO:0016741	transferase activity, transferring one-carbon groups	40/4208	215/18639	0.186046511627907	0.824078167830931	0.933577292620506	1
GO:0016859	cis-trans isomerase activity	6/4208	42/18639	0.142857142857143	0.632774307441608	0.936239262386562	1
GO:0004970	glutamate-gated receptor activity	2/4208	18/18639	0.111111111111111	0.492157794676806	0.937639697014417	1
GO:0005372	water transmembrane transporter activity	2/4208	18/18639	0.111111111111111	0.492157794676806	0.937639697014417	1
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	2/4208	18/18639	0.111111111111111	0.492157794676806	0.937639697014417	1
GO:0070064	proline-rich region binding	2/4208	18/18639	0.111111111111111	0.492157794676806	0.937639697014417	1
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	9/4208	59/18639	0.152542372881356	0.675674260488496	0.939319563952848	1
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	1/4208	11/18639	0.0909090909090909	0.402674559281023	0.940126015893435	1
GO:0008172	S-methyltransferase activity	1/4208	11/18639	0.0909090909090909	0.402674559281023	0.940126015893435	1
GO:0032404	mismatch repair complex binding	1/4208	11/18639	0.0909090909090909	0.402674559281023	0.940126015893435	1
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/4208	11/18639	0.0909090909090909	0.402674559281023	0.940126015893435	1
GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/4208	11/18639	0.0909090909090909	0.402674559281023	0.940126015893435	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/4208	11/18639	0.0909090909090909	0.402674559281023	0.940126015893435	1
GO:1900750	oligopeptide binding	1/4208	11/18639	0.0909090909090909	0.402674559281023	0.940126015893435	1
GO:1990948	ubiquitin ligase inhibitor activity	1/4208	11/18639	0.0909090909090909	0.402674559281023	0.940126015893435	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	21/4208	122/18639	0.172131147540984	0.762441173720626	0.940781438766875	1
GO:0005184	neuropeptide hormone activity	4/4208	31/18639	0.129032258064516	0.571538084140807	0.942339663262554	1
GO:0019843	rRNA binding	10/4208	65/18639	0.153846153846154	0.681449254167885	0.943475014390722	1
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	2/4208	19/18639	0.105263157894737	0.466254752851711	0.949476153223288	1
GO:0042800	histone H3K4 methyltransferase activity	2/4208	19/18639	0.105263157894737	0.466254752851711	0.949476153223288	1
GO:0099589	serotonin receptor activity	2/4208	19/18639	0.105263157894737	0.466254752851711	0.949476153223288	1
GO:0008170	N-methyltransferase activity	16/4208	98/18639	0.163265306122449	0.723170637076123	0.950210141350205	1
GO:0160041	neuropeptide activity	4/4208	32/18639	0.125	0.553677519011407	0.95136306274072	1
GO:0015078	proton transmembrane transporter activity	33/4208	185/18639	0.178378378378378	0.790112783886548	0.952373536959777	1
GO:0016651	oxidoreductase activity, acting on NAD(P)H	14/4208	88/18639	0.159090909090909	0.704680478741791	0.952970877609813	1
GO:0000995	RNA polymerase III general transcription initiation factor activity	1/4208	12/18639	0.0833333333333333	0.369118346007605	0.953651339337735	1
GO:0003720	telomerase activity	1/4208	12/18639	0.0833333333333333	0.369118346007605	0.953651339337735	1
GO:0004300	enoyl-CoA hydratase activity	1/4208	12/18639	0.0833333333333333	0.369118346007605	0.953651339337735	1
GO:0008179	adenylate cyclase binding	1/4208	12/18639	0.0833333333333333	0.369118346007605	0.953651339337735	1
GO:0036009	protein-glutamine N-methyltransferase activity	1/4208	12/18639	0.0833333333333333	0.369118346007605	0.953651339337735	1
GO:0015464	acetylcholine receptor activity	2/4208	20/18639	0.1	0.442942015209126	0.959147960467884	1
GO:0140664	ATP-dependent DNA damage sensor activity	2/4208	20/18639	0.1	0.442942015209126	0.959147960467884	1
GO:0005272	sodium channel activity	7/4208	51/18639	0.137254901960784	0.607959628718408	0.960473901722895	1
GO:0016597	amino acid binding	7/4208	51/18639	0.137254901960784	0.607959628718408	0.960473901722895	1
GO:0046906	tetrapyrrole binding	26/4208	152/18639	0.171052631578947	0.75766397338403	0.960586130531591	1
GO:0140223	general transcription initiation factor activity	10/4208	68/18639	0.147058823529412	0.651385316484008	0.961180028178993	1
GO:0008395	steroid hydroxylase activity	3/4208	27/18639	0.111111111111111	0.492157794676806	0.961418541536624	1
GO:0015252	proton channel activity	3/4208	27/18639	0.111111111111111	0.492157794676806	0.961418541536624	1
GO:0003964	RNA-directed DNA polymerase activity	1/4208	13/18639	0.0769230769230769	0.340724627083943	0.964121901643357	1
GO:0005338	nucleotide-sugar transmembrane transporter activity	1/4208	13/18639	0.0769230769230769	0.340724627083943	0.964121901643357	1
GO:0008417	fucosyltransferase activity	1/4208	13/18639	0.0769230769230769	0.340724627083943	0.964121901643357	1
GO:0009982	pseudouridine synthase activity	1/4208	13/18639	0.0769230769230769	0.340724627083943	0.964121901643357	1
GO:0045159	myosin II binding	1/4208	13/18639	0.0769230769230769	0.340724627083943	0.964121901643357	1
GO:0046975	histone H3K36 methyltransferase activity	1/4208	13/18639	0.0769230769230769	0.340724627083943	0.964121901643357	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	6/4208	46/18639	0.130434782608696	0.577750454620598	0.965004203558824	1
GO:0051427	hormone receptor binding	4/4208	34/18639	0.117647058823529	0.521108253187206	0.965632678711636	1
GO:0022836	gated channel activity	59/4208	318/18639	0.185534591194969	0.821810657149006	0.966241000237468	1
GO:0005248	voltage-gated sodium channel activity	2/4208	21/18639	0.0952380952380952	0.421849538294405	0.967028973797016	1
GO:0051428	peptide hormone receptor binding	2/4208	21/18639	0.0952380952380952	0.421849538294405	0.967028973797016	1
GO:1904047	S-adenosyl-L-methionine binding	2/4208	21/18639	0.0952380952380952	0.421849538294405	0.967028973797016	1
GO:0008527	taste receptor activity	3/4208	28/18639	0.107142857142857	0.474580730581206	0.968141812808838	1
GO:0051537	2 iron, 2 sulfur cluster binding	3/4208	28/18639	0.107142857142857	0.474580730581206	0.968141812808838	1
GO:0008227	G protein-coupled amine receptor activity	5/4208	41/18639	0.121951219512195	0.540173189279421	0.970146590418015	1
GO:0016860	intramolecular oxidoreductase activity	7/4208	53/18639	0.132075471698113	0.585017755936581	0.970527297587786	1
GO:0004252	serine-type endopeptidase activity	30/4208	176/18639	0.170454545454545	0.755014798651918	0.971306343791396	1
GO:0008392	arachidonate epoxygenase activity	1/4208	14/18639	0.0714285714285714	0.316387153720804	0.972227508745512	1
GO:0042813	Wnt receptor activity	1/4208	14/18639	0.0714285714285714	0.316387153720804	0.972227508745512	1
GO:0061783	peptidoglycan muralytic activity	1/4208	14/18639	0.0714285714285714	0.316387153720804	0.972227508745512	1
GO:0016874	ligase activity	28/4208	167/18639	0.167664670658683	0.742657271009312	0.974296468916928	1
GO:0005254	chloride channel activity	12/4208	83/18639	0.144578313253012	0.640398094278254	0.976411788345081	1
GO:0020037	heme binding	23/4208	142/18639	0.161971830985915	0.717441292240133	0.976425976808824	1
GO:0008020	G protein-coupled photoreceptor activity	1/4208	15/18639	0.0666666666666667	0.295294676806084	0.978502227843439	1
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/4208	15/18639	0.0666666666666667	0.295294676806084	0.978502227843439	1
GO:0017081	chloride channel regulator activity	1/4208	15/18639	0.0666666666666667	0.295294676806084	0.978502227843439	1
GO:0140103	catalytic activity, acting on a glycoprotein	2/4208	23/18639	0.0869565217391304	0.385166969747066	0.978629194160464	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	5/4208	43/18639	0.116279069767442	0.515048854894332	0.978648481996298	1
GO:0008276	protein methyltransferase activity	14/4208	95/18639	0.147368421052632	0.652756653992395	0.979057474865177	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	7/4208	56/18639	0.125	0.553677519011407	0.981284023046056	1
GO:0022853	active monoatomic ion transmembrane transporter activity	18/4208	118/18639	0.152542372881356	0.675674260488496	0.981904491525517	1
GO:0017147	Wnt-protein binding	3/4208	31/18639	0.0967741935483871	0.428653563105605	0.982270083593042	1
GO:0008391	arachidonate monooxygenase activity	1/4208	16/18639	0.0625	0.276838759505703	0.983359542342731	1
GO:0019841	retinol binding	1/4208	16/18639	0.0625	0.276838759505703	0.983359542342731	1
GO:0022834	ligand-gated channel activity	31/4208	188/18639	0.164893617021277	0.73038311018526	0.984498154345921	1
GO:0004549	tRNA-specific ribonuclease activity	1/4208	17/18639	0.0588235294117647	0.260554126593603	0.987119572725687	1
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	1/4208	17/18639	0.0588235294117647	0.260554126593603	0.987119572725687	1
GO:0019198	transmembrane receptor protein phosphatase activity	1/4208	17/18639	0.0588235294117647	0.260554126593603	0.987119572725687	1
GO:0042923	neuropeptide binding	3/4208	33/18639	0.0909090909090909	0.402674559281023	0.988107067703222	1
GO:0015276	ligand-gated monoatomic ion channel activity	30/4208	186/18639	0.161290322580645	0.714422605176009	0.988531064096158	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	6/4208	53/18639	0.113207547169811	0.501443790802784	0.988637964482727	1
GO:0008066	glutamate receptor activity	2/4208	26/18639	0.0769230769230769	0.340724627083943	0.98896594403888	1
GO:0022851	GABA-gated chloride ion channel activity	1/4208	18/18639	0.0555555555555556	0.246078897338403	0.990030153649879	1
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	3/4208	34/18639	0.0882352941176471	0.390831189890405	0.990282008573376	1
GO:0019825	oxygen binding	3/4208	34/18639	0.0882352941176471	0.390831189890405	0.990282008573376	1
GO:0004364	glutathione transferase activity	2/4208	27/18639	0.0740740740740741	0.328105196451204	0.991169736239061	1
GO:0005104	fibroblast growth factor receptor binding	2/4208	27/18639	0.0740740740740741	0.328105196451204	0.991169736239061	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	9/4208	73/18639	0.123287671232877	0.546092895463305	0.991291613312091	1
GO:0004890	GABA-A receptor activity	1/4208	19/18639	0.0526315789473684	0.233127376425856	0.992283153673579	1
GO:0140939	histone H4 methyltransferase activity	1/4208	20/18639	0.05	0.221471007604563	0.99402711121072	1
GO:0008528	G protein-coupled peptide receptor activity	17/4208	122/18639	0.139344262295082	0.617214283488126	0.994106973502706	1
GO:0001653	peptide receptor activity	18/4208	128/18639	0.140625	0.622887208887833	0.994392386163924	1
GO:0099095	ligand-gated monoatomic anion channel activity	4/4208	47/18639	0.0851063829787234	0.376971927837554	0.996982739627614	1
GO:0140101	catalytic activity, acting on a tRNA	19/4208	139/18639	0.136690647482014	0.605460308559236	0.997123535124673	1
GO:0008188	neuropeptide receptor activity	4/4208	48/18639	0.0833333333333333	0.369118346007605	0.997522455324108	1
GO:0004497	monooxygenase activity	13/4208	106/18639	0.122641509433962	0.543230773369682	0.997717390344096	1
GO:0004812	aminoacyl-tRNA ligase activity	3/4208	41/18639	0.0731707317073171	0.324103913567653	0.997721074836455	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	3/4208	41/18639	0.0731707317073171	0.324103913567653	0.997721074836455	1
GO:0098960	postsynaptic neurotransmitter receptor activity	7/4208	69/18639	0.101449275362319	0.44936146470491	0.997772170509488	1
GO:0022824	transmitter-gated monoatomic ion channel activity	6/4208	63/18639	0.0952380952380952	0.421849538294405	0.998001647564605	1
GO:0022835	transmitter-gated channel activity	6/4208	63/18639	0.0952380952380952	0.421849538294405	0.998001647564605	1
GO:0000030	mannosyltransferase activity	1/4208	25/18639	0.04	0.17717680608365	0.998341157561663	1
GO:0030280	structural constituent of skin epidermis	2/4208	37/18639	0.0540540540540541	0.239428116329257	0.999095790221933	1
GO:0005179	hormone activity	16/4208	132/18639	0.121212121212121	0.536899412374698	0.999285716996801	1
GO:0009055	electron transfer activity	13/4208	116/18639	0.112068965517241	0.496400534286089	0.99948406251968	1
GO:0003730	mRNA 3'-UTR binding	38/4208	262/18639	0.145038167938931	0.642434983891098	0.999631928575458	1
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	4/4208	58/18639	0.0689655172413793	0.305477251868362	0.99967391446696	1
GO:0030594	neurotransmitter receptor activity	9/4208	97/18639	0.0927835051546392	0.410977127513622	0.999828534331607	1
GO:0015020	glucuronosyltransferase activity	1/4208	34/18639	0.0294117647058824	0.130277063296802	0.99983484451057	1
GO:0003954	NADH dehydrogenase activity	1/4208	44/18639	0.0227272727272727	0.100668639820256	0.999987293990566	1
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	1/4208	68/18639	0.0147058823529412	0.0651385316484008	0.999999973214521	1
GO:0030527	structural constituent of chromatin	2/4208	98/18639	0.0204081632653061	0.0903963296345154	0.999999999644381	1
GO:0003735	structural constituent of ribosome	5/4208	175/18639	0.0285714285714286	0.126554861488322	0.999999999999991	1
GO:0030371	translation repressor activity	6/4208	329/18639	0.0182370820668693	0.0807796988223329	1	1
GO:0045182	translation regulator activity	14/4208	356/18639	0.0393258426966292	0.17419068013842	1	1