category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
NA	NA	hsa04518	Integrin signaling	30/343	154/9376	5.32505395479156	FN1/FLT1/FBN1/VEGFA/LAMB1/THBS1/PDGFD/EGFR/LAMA3/LAMB3/PIK3R1/ITGA5/ACTN1/FLNB/IGF1R/FERMT2/PIK3CB/ITGB6/PTK2/AKT3/CDH1/MET/ITGA6/ACTN4/LAMB4/NPNT/TNC/FERMT1/ITGB1/LAMC2	10.5452292162294
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	30/343	203/9376	4.03969610363498	FN1/FLT1/VEGFA/LAMB1/THBS1/PDGFD/EGFR/LAMA3/LAMB3/PIK3R1/ITGA5/ACTN1/FLNB/IGF1R/DIAPH1/PIK3CB/ITGB6/PTK2/AKT3/MET/ITGA6/ACTN4/PIP5K1B/PPP1R12B/LAMB4/TNC/ITGB1/CAPN2/LAMC2/PTEN	8.53177084290833
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	31/343	233/9376	3.63688234337266	FN1/SYNE2/FBN1/THBS1/TPM1/ITGA5/DSP/DIAPH1/NID1/ITGB6/PDLIM1/PKP2/ACTG2/DSG2/FBN2/JUP/SDC4/DIAPH3/PDLIM3/ITGA6/DIAPH2/TMEM43/COL11A1/ACTC1/ITGB1/CSRP1/MYH9/DMD/PDLIM5/DES/AMPD3	7.94220414528928
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	27/343	204/9376	3.61790430457897	TIMP3/FN1/VEGFA/THBS1/EZR/EGFR/PIK3R1/ITGA5/IGF1R/PLCG2/PIK3CB/PTK2/RRAS2/AKT3/WNT7A/SDC4/IGF2/TIAM1/MET/CTTN/PPP1R12B/CTSL/CDKN1A/MDM2/PTPN11/ITGB1/GAB1	7.36636986560736
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	17/343	93/9376	4.99677105865388	FN1/LAMB1/LAMA3/PTGS2/LAMB3/PIK3R1/PIK3CB/PTK2/AKT3/ITGA6/LAMB4/CDKN1A/BIRC7/GADD45A/ITGB1/LAMC2/PTEN	7.54785005738358
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	27/343	232/9376	3.18126068161255	FN1/PDGFD/EZR/EGFR/PIK3R1/ITGA5/ACTN1/LPAR1/RGCC/DIAPH1/PIK3CB/ITGB6/PTK2/RRAS2/AKT3/KNG1/DIAPH3/TIAM1/ITGA6/ACTN4/DIAPH2/PIP5K1B/PPP1R12B/BDKRB2/BAIAP2/ITGB1/MYH9	6.55541435647109
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	35/343	362/9376	2.64291351899876	FN1/FLT1/VEGFA/LAMB1/THBS1/PDGFD/INSR/EGFR/LAMA3/LAMB3/PIK3R1/ITGA5/LPAR1/JAK2/IGF1R/PIK3CB/ITGB6/PTK2/AKT3/IGF2/CREB3L2/MET/ITGA6/CREB5/LAMB4/EREG/CDKN1A/PRLR/YWHAQ/MDM2/TNC/JAK1/ITGB1/LAMC2/PTEN	6.21193502944116
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	16/343	93/9376	4.7028433493213	INSR/EGFR/TCF7L2/ACTN1/IGF1R/PTPRF/CDH1/SORBS1/MET/PARD3/ACTN4/SMURF1/BAIAP2/NECTIN4/SMAD3/AFDN	6.99277140884579
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	19/343	133/9376	3.90503956684715	FOXO1/FBXO32/INSR/EGFR/IRS2/PIK3R1/IGF1R/PIK3CB/GABARAPL1/AKT3/HOMER1/PLK2/PRKAG2/CDKN1A/GADD45A/MDM2/DEPP1/SMAD3/PTEN	6.5748839082903
NA	NA	hsa04382	Cornified envelope formation	25/343	217/9376	3.1492254571348	PCSK6/KRT8/KRT6A/KRT7/KRT19/LAMA3/COL17A1/LAMB3/DSP/CLDN4/PKP2/DSG2/JUP/ITGA6/PRSS8/KRT17/PKP3/CLDN3/CLDN1/KRT14/KRT18/S100A8/CLDN7/S100A10/LAMC2	6.24172321953449
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	17/343	110/9376	4.22454280413464	SERPINE1/FLT1/VEGFA/TF/INSR/EGFR/PIK3R1/IGF1R/PLCG2/PIK3CB/PFKP/ALDOB/AKT3/EGLN3/HK2/CDKN1A/TFRC	6.6288018032488
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	32/343	333/9376	2.62681340232361	HLA-G/FN1/VEGFA/FOXO1/LAMB1/THBS1/EGFR/LAMA3/PTGS2/TCF7L2/LAMB3/PIK3R1/ITGA5/PIK3CB/ITGB6/PTK2/AKT3/WNT7A/CREB3L2/ITGA6/PARD3/CREB5/LAMB4/CDKN1A/LLGL2/MDM2/TNC/JAK1/ITGB1/LAMC2/PTEN/PARD6B	5.89006769332802
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	14/343	80/9376	4.78367346938775	VEGFA/PDGFD/EGFR/PIK3R1/NRG2/JAK2/IGF1R/PLCG2/PIK3CB/AKT3/MET/JAK1/GAB1/PTEN	6.62258100079279
NA	NA	hsa04519	Cadherin signaling	35/343	404/9376	2.36815518286522	TEAD1/KRT8/KRT6A/KRT7/KRT19/EGFR/TCF7L2/DSP/ACTN1/LIMA1/IGF1R/PTK2/PKP2/DSG2/RRAS2/PCDH7/WNT7A/JUP/CDH1/MET/ACTN4/MYO1E/DSC3/KRT17/WWC1/PKP3/WWTR1/YAP1/KRT14/YWHAQ/KRT18/STK3/AFDN/TMC1/DES	5.47769823230804
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	14/343	89/9376	4.29993120843843	FN1/LAMB1/THBS1/LAMA3/LAMB3/ITGA5/ITGB6/SDC4/ITGA6/LAMB4/NPNT/TNC/ITGB1/LAMC2	6.09507227981209
NA	NA	hsa04517	IgSF CAM signaling	28/343	299/9376	2.5598252678998	FOXO1/EZR/TRIO/PIK3R1/RASA1/ITGA5/ACTN1/IL1RAP/PLCG2/PIK3CB/PTK2/GRIP1/AKT3/TJP2/PTPRF/CDH1/SORBS1/PARD3/ACTN4/RAPGEF2/F11R/BAIAP2/PTPN11/ITGB1/NECTIN4/AFDN/MYH9/PARD6B	5.34142421366455
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	24/343	238/9376	2.75649851777446	FLT1/VEGFA/PDGFD/INSR/PLA2G4A/EGFR/RASAL2/PIK3R1/RASA1/PLA2G5/IGF1R/PLCG2/PIK3CB/RRAS2/AKT3/IGF2/TIAM1/PLA2G2A/MET/RASGRF2/KSR1/PTPN11/GAB1/AFDN	5.34844313135508
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	15/343	109/9376	3.76173536255918	FOXO1/INSR/IRS2/PIK3R1/PIK3CB/AKT3/PTPRF/CREB3L2/PRKAG2/CREB5/GFPT1/SLC27A6/PTPN11/AGT/PTEN	5.6512226921978
Human Diseases	Cancer: specific types	hsa05218	Melanoma	12/343	73/9376	4.49347018650905	PDGFD/EGFR/PIK3R1/IGF1R/PIK3CB/AKT3/CDH1/MET/CDKN1A/GADD45A/MDM2/PTEN	5.83880073468357
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	19/343	170/9376	3.05511919053336	EZR/CLDN4/ACTN1/TJP2/TIAM1/PRKAG2/PARD3/ACTN4/CTTN/RAPGEF2/F11R/CLDN3/CLDN1/LLGL2/CLDN7/ITGB1/AFDN/MYH9/PARD6B	5.26917573494802
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	15/343	116/9376	3.53473409068061	EZR/PIK3R1/CLDN4/ACTN1/PLCG2/PIK3CB/PTK2/ACTN4/F11R/CLDN3/CLDN1/CLDN7/PTPN11/ITGB1/AFDN	5.35269626384927
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	12/343	78/9376	4.20542722583539	FN1/PIK3R1/ITGA5/PIK3CB/PTK2/ARHGAP10/CLTB/CDH1/MET/CTTN/ITGB1/GAB1	5.53930329557017
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	12/343	86/9376	3.81422469319954	TCF7L2/ITGA5/DSP/CACNA2D3/ITGB6/PKP2/DSG2/JUP/ITGA6/ITGB1/DMD/DES	5.10877564899293
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	11/343	75/9376	4.0091739552964	SERPINE1/THBS1/PERP/IGFBP3/SESN1/SFN/PPP1R13L/CDKN1A/GADD45A/MDM2/PTEN	5.09835176781942
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	12/343	90/9376	3.644703595724	FOXO1/INSR/IRS2/PIK3R1/IGF1R/PIK3CB/AKT3/ULK1/SESN1/CREB3L2/PRKAG2/CREB5	4.91247794798379
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	13/343	106/9376	3.35243962814236	FOXO1/PDGFD/EGFR/TCF7L2/PIK3R1/IGF1R/PIK3CB/AKT3/CREB3L2/CREB5/CDKN1A/MDM2/PTEN	4.74622415643717
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	14/343	122/9376	3.13683506189361	FOXO1/INSR/IRS2/PIK3R1/IGF1R/PIK3CB/PFKP/AKT3/ULK1/CREB3L2/PRKAG2/CREB5/TBC1D1/LEP	4.62916714365844
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	22/343	253/9376	2.37698060590696	FOXO1/EGFR/PIK3R1/ITGA5/ACTN1/DIAPH1/PLCG2/PIK3CB/PTK2/IL1R1/AKT3/CAST/ACTN4/CTTN/FNBP1L/HK2/CUL1/MDM2/ITGB1/CAPN2/CYTH3/RRAGC	4.32649234596266
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	13/343	110/9376	3.23053273257355	FBN1/THBS1/TF/INHBA/BMP2/ID4/LTBP1/SMURF1/SKIL/CUL1/SMAD3/INHBB/TFRC	4.58538164881239
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	16/343	157/9376	2.78576071010752	SERPINE1/HLA-G/FOXO1/PIK3R1/HIPK3/PIK3CB/RRAS2/AKT3/IGFBP3/CDKN1A/GADD45A/MDM2/RAD50/SMAD3/CAPN2/PTEN	4.39691302854644
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	9/343	59/9376	4.16978801205712	EGFR/TCF7L2/PIK3R1/PIK3CB/AKT3/CDH1/CDKN1A/GADD45A/PTEN	4.75921001454963
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	19/343	212/9376	2.44985972825788	FLT1/VEGFA/THBS1/PDGFD/INSR/EGFR/PIK3R1/LPAR1/IGF1R/PIK3CB/AKT3/CDH1/TIAM1/MET/PARD3/RAPGEF2/ITGB1/AFDN/PARD6B	4.1607159739934
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	12/343	101/9376	3.24775567935802	SERPINE1/FN1/VEGFA/FOXO1/PIK3R1/JAK2/DIAPH1/PLCG2/PIK3CB/AKT3/AGT/SMAD3	4.42557315964597
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	15/343	149/9376	2.75187352026141	PDGFD/INSR/PLA2G4A/EGFR/PIK3R1/LPAR1/PLCG2/PIK3CB/RRAS2/AKT3/PIP5K1B/PTPN11/AGT/GAB1/CYTH3	4.20031939105564
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	12/343	103/9376	3.18469246228311	FN1/LAMB1/LAMA3/LAMB3/PIK3R1/ACTN1/PIK3CB/PTK2/IL1R1/ACTN4/LAMB4/LAMC2	4.34425676242147
Human Diseases	Cancer: specific types	hsa05214	Glioma	10/343	76/9376	3.59674696946448	EGFR/PIK3R1/IGF1R/PLCG2/PIK3CB/AKT3/CDKN1A/GADD45A/MDM2/PTEN	4.42906086433186
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	10/343	77/9376	3.55003596986104	PIK3R1/PIK3CB/CTBP2/AKT3/CDKN1A/GADD45A/MDM2/PTPN11/SMAD3/BCR	4.3781459820855
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	15/343	157/9376	2.6116506657258	SERPINE1/TEAD1/TCF7L2/BMP2/WNT7A/CDH1/PARD3/WWC1/WWTR1/YAP1/YWHAQ/LLGL2/STK3/SMAD3/PARD6B	3.96821800898994
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	12/343	112/9376	2.92877967513536	LAMB1/LAMA3/LAMB3/JAK2/AKT3/ITGA6/LAMB4/HLA-DRB5/BIRC7/JAK1/ITGB1/LAMC2	4.00137313686667
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	11/343	99/9376	3.03725299643667	TPM1/ITGA5/CACNA2D3/ITGB6/PRKAG2/ITGA6/ACTC1/ITGB1/AGT/DMD/DES	3.9707768144709
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	9/343	70/9376	3.51453561016243	VEGFA/PIK3R1/PIK3CB/AKT3/EGLN3/MET/CDKN1A/PTPN11/GAB1	4.11473602947269
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	10/343	86/9376	3.17852057766628	EGFR/PIK3R1/NRG2/PLCG2/PIK3CB/PTK2/AKT3/EREG/CDKN1A/GAB1	3.9547563152671
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	8/343	59/9376	3.70647823293967	INSR/IRS2/PTGS2/PIK3R1/PIK3CB/MGLL/AKT3/PDE3B	4.06358351453532
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	15/343	170/9376	2.41193620305265	EGFR/TCF7L2/PIK3R1/IGF1R/PLCG2/PIK3CB/AKT3/WNT7A/IGF2/MET/CDKN1A/GADD45A/SMAD3/GAB1/PTEN	3.62010145917078
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	8/343	60/9376	3.644703595724	VEGFA/PLA2G4A/PTGS2/PIK3R1/PLCG2/PIK3CB/PTK2/AKT3	4.00455796226286
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	13/343	138/9376	2.57506232306587	FOXO1/INSR/IRS2/PRKAR2B/PIK3R1/PIK3CB/AKT3/PTPRF/PRKAG2/SORBS1/HK2/TRIP10/PDE3B	3.63216024180658
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	13/343	139/9376	2.55653669484238	KRT19/EGFR/PIK3R1/FKBP5/PIK3CB/NCOA1/AKT3/CREB3L2/KRT17/CREB5/KRT14/KRT18/GREB1	3.60261609479089
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	8/343	62/9376	3.52713251199097	FOXO1/INSR/IRS2/PIK3R1/IGF1R/PIK3CB/AKT3/PRKAG2	3.8902045378451
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	9/343	77/9376	3.19503237287494	VEGFA/EGFR/PIK3R1/PIK3CB/AKT3/CDKN1A/GADD45A/JAK1/SMAD3	3.7686418064031
Metabolism	Carbohydrate metabolism	hsa00520	Amino sugar and nucleotide sugar metabolism	6/343	38/9376	4.31609636335737	UGP2/HEXB/UAP1/HK2/PGM1/GFPT1	3.99124786248223
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	16/343	200/9376	2.1868221574344	EZR/BAIAP2L1/CLDN4/LPAR1/IL1R1/MYO1E/CTTN/CLDN3/CLDN1/MYO5B/BAIAP2/CLDN7/PTPN11/ITGB1/CYTH3/MYH9	3.30590701693586
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	21/343	300/9376	1.9134693877551	FLT1/VEGFA/PDGFD/INSR/PLA2G4A/EGFR/RASA1/IL1RAP/IGF1R/CACNA2D3/IL1R1/RRAS2/AKT3/IGF2/MET/RASGRF2/RAPGEF2/EREG/PTPRR/GADD45A/STK3	3.13345941973344
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	13/343	150/9376	2.3690573372206	EGFR/TCF7L2/PIK3R1/PIK3CB/AKT3/WNT7A/JUP/CDH1/MET/CDKN1A/GADD45A/SMAD3/GAB1	3.29364838969399
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	6/343	41/9376	4.00028443433122	VEGFA/THBS1/EGFR/CDH1/CDKN1A/MDM2	3.75157721193722
Environmental Information Processing	Signal transduction	hsa04392	Hippo signaling pathway - multiple species	5/343	29/9376	4.71297878757414	TEAD1/WWC1/WWTR1/YAP1/STK3	3.90213273968092
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	6/343	42/9376	3.90503956684715	TF/SAT1/SLC39A14/CP/ACSL3/TFRC	3.67671097880117
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	8/343	71/9376	3.08003120765409	EGFR/PIK3R1/PIK3CB/PFKP/AKT3/MET/HK2/PTEN	3.42813194953256
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	9/343	87/9376	2.82778727254449	EGFR/TCF7L2/PIK3R1/PIK3CB/AKT3/EREG/CDKN1A/GADD45A/SMAD3	3.33747089346026
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	10/343	105/9376	2.60335971123143	TPM1/ITGA5/CACNA2D3/ITGB6/ITGA6/ACTC1/ITGB1/AGT/DMD/DES	3.21943023719222
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	11/343	122/9376	2.46465612005926	FOXO1/PIK3R1/THRB/PLCG2/PIK3CB/PFKP/NCOA1/AKT3/MED13L/MDM2/DIO2	3.17298143813132
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	8/343	73/9376	2.99564679100603	EGFR/PIK3R1/PLCG2/PIK3CB/AKT3/MET/CDKN1A/GADD45A	3.33541817373822
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	12/343	144/9376	2.2779397473275	INHBA/PIK3R1/JAK2/IGF1R/PIK3CB/ID4/AKT3/WNT7A/SKIL/JAK1/SMAD3/INHBB	3.01134434295353
NA	NA	hsa03272	Virion - Hepatitis viruses	6/343	48/9376	3.41690962099125	EGFR/CLDN4/CLDN3/CLDN1/EPCAM/CLDN7	3.27117255306975
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	9/343	98/9376	2.51038257868745	PLA2G4A/PIK3R1/PLCG2/PIK3CB/AKT3/ASAP2/ASAP1/ASAP3/PIP5K1B	2.928798642173
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	9/343	99/9376	2.48502517890273	PDGFD/PLA2G4A/EGFR/PIK3R1/PIK3CB/AKT3/PIP5K1B/SLC44A2/SLC22A3	2.89443852069738
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	17/343	250/9376	1.85879883381924	HLA-G/EGFR/RAB11FIP3/IGF1R/CLTB/ASAP2/ASAP1/ASAP3/PARD3/PIP5K1B/SMURF1/WASHC2A/MDM2/SMAD3/CYTH3/TFRC/PARD6B	2.68187116747949
Metabolism	Global and overview maps	hsa01250	Biosynthesis of nucleotide sugars	5/343	37/9376	3.69395634701757	UGP2/UAP1/HK2/PGM1/GFPT1	3.19932177257565
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	6/343	52/9376	3.15407041937654	APOA2/APOC3/APOB/APOA1/APOC2/APOH	3.03512882544555
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	8/343	85/9376	2.57273194992283	ADK/UPP1/GDA/UCK2/CDA/CTPS1/NT5E/AMPD3	2.83824339236205
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	12/343	158/9376	2.07609698490608	INSR/PIK3R1/LPIN1/GRB10/IGF1R/PIK3CB/AKT3/WNT7A/ULK1/CLIP1/RRAGC/PTEN	2.6581427447013
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	7/343	70/9376	2.733527696793	IRS2/JAK2/AKT3/PRKAG2/PTPN11/LEP/ACSL3	2.83671022325359
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	10/343	122/9376	2.24059647278115	IRS2/PIK3R1/JAK2/PLCG2/PIK3CB/PTK2/AKT3/IGFBP3/CREB3L2/CREB5	2.68758620295561
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	12/343	160/9376	2.05014577259475	HLA-G/CLDN4/PTPRF/SDC4/CDH1/ITGA6/HLA-DRB5/F11R/CLDN3/CLDN1/CLDN7/ITGB1	2.61068840210331
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	9/343	105/9376	2.34302374010829	PTGS2/PIK3R1/PLCG2/PIK3CB/RRAS2/AKT3/KSR1/MDM2/PTPN11	2.69669445220799
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	8/343	88/9376	2.48502517890273	SERPINE1/SERPINE2/SERPINC1/KNG1/SERPING1/TFPI/BDKRB2/CFH	2.72728637652902
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	8/343	90/9376	2.42980239714934	EGFR/PIK3R1/JAK2/PIK3CB/AKT3/PTPN11/JAK1/PTEN	2.65582606584979
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	13/343	184/9376	1.9312967422994	PIK3R1/RASA1/SEMA5A/PLCG2/PIK3CB/PTK2/MET/PARD3/SEMA3C/PTPN11/ITGB1/SEMA7A/PARD6B	2.48604325405217
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	15/343	227/9376	1.80629583488524	HLA-G/VEGFA/EGFR/PTGS2/PIK3R1/AKAP13/PIK3CB/PTK2/IL1R1/AKT3/CREB3L2/CREB5/CDKN1A/MDM2/JAK1	2.39627813078053
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	11/343	148/9376	2.03167599085966	EGFR/TCF7L2/PIK3R1/IGF1R/PIK3CB/NCOA1/AKT3/WNT7A/CDKN1A/GADD45A/PTEN	2.46511441707367
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	7/343	76/9376	2.51772287862513	APOA2/APOC3/APOA1/PLIN2/SORBS1/SLC27A6/ACSL3	2.58865691716046
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	12/343	169/9376	1.94096641192403	IRS2/PIK3R1/IGF1R/PIK3CB/GABARAPL1/RRAS2/AKT3/ULK1/CTSL/OPTN/RRAGC/PTEN	2.40533236661947
NA	NA	hsa03273	Virion - Lassa virus and SFTS virus	3/343	17/9376	4.8238724061053	PCDH7/MYH9/TFRC	3.07489168855828
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	7/343	78/9376	2.45316588173731	PLCG2/PIK3CB/IMPA2/PIP5K1B/IP6K3/MTMR1/PTEN	2.51121800327872
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	9/343	115/9376	2.13928254531626	EGFR/AKAP13/GATA3/CREB3L2/CREB5/CDKN1A/SLC34A2/MMP14/OXSR1	2.39534522876012
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	10/343	134/9376	2.03994604238284	PLA2G4A/KCNMA1/PLA2G5/CALD1/ADM/ACTG2/PLA2G2A/PPP1R12B/AGT/MYH9	2.36263654176288
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	8/343	98/9376	2.23145118105551	PIK3R1/PLCG2/PIK3CB/IMPA2/PIP5K1B/IP6K3/MTMR1/PTEN	2.38791985412861
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	5/343	47/9376	2.90800818807766	INSR/IRS2/PIK3R1/PIK3CB/HK2	2.5552200680715
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	11/343	156/9376	1.92748747850789	EGFR/PIK3R1/CLDN4/PIK3CB/AKT3/CDKN1A/CLDN3/CLDN1/YWHAQ/CLDN7/JAK1	2.2762585333686
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	19/343	323/9376	1.60795746870177	TIMP3/VEGFA/THBS1/EZR/EGFR/IRS2/PTGS2/TPM1/PIK3R1/ITGA5/PLCG2/PIK3CB/SLC7A1/MET/CDKN1A/MDM2/TNC/PTEN/EZH2	2.16668058713641
Metabolism	Carbohydrate metabolism	hsa00052	Galactose metabolism	4/343	32/9376	3.41690962099125	UGP2/PFKP/HK2/PGM1	2.66861349497456
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	8/343	99/9376	2.20891127013576	EGFR/PIK3R1/IGF1R/PIK3CB/PTK2/AKT3/CDKN1A/MDM2	2.35626937381062
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	8/343	99/9376	2.20891127013576	PLA2G4A/PIK3R1/IL1RAP/PLCG2/PIK3CB/IL1R1/KNG1/BDKRB2	2.35626937381062
NA	NA	hsa04081	Hormone signaling	14/343	219/9376	1.74746062808685	INSR/IRS2/PIK3R1/CRH/JAK2/IGF1R/THRB/PIK3CB/IGF2/OXTR/PRLR/AGT/DIO2/LEP	2.18097388268583
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	12/343	178/9376	1.84282766075933	TCF7L2/SFRP1/DKK1/CTBP2/TLE1/WNT7A/NOTUM/FOSL1/CUL1/TBL1X/SMAD3/PORCN	2.21217139316915
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	13/343	201/9376	1.76795323673179	ZBTB16/FLT1/FOXO1/IGF1R/AFF1/PTK2/JUP/IGFBP3/MET/CDKN1A/GADD45A/MDM2/ASPSCR1	2.1446007845616
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	6/343	68/9376	2.41193620305265	ZBTB16/TCF7L2/PIK3R1/PIK3CB/AKT3/JUP	2.27697381419286
Metabolism	Carbohydrate metabolism	hsa00500	Starch and sucrose metabolism	4/343	36/9376	3.03725299643667	UGP2/GBE1/HK2/PGM1	2.38637928582029
Metabolism	Glycan biosynthesis and metabolism	hsa00512	Mucin type O-glycan biosynthesis	4/343	36/9376	3.03725299643667	GALNT15/GALNT2/GALNT3/GALNT6	2.38637928582029
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	11/343	168/9376	1.78980980147161	EGFR/PIK3R1/JAK2/PIK3CB/AKT3/CDKN1A/PRLR/CLCF1/PTPN11/JAK1/LEP	2.01284900677243
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	4/343	37/9376	2.95516507761406	TCF7L2/CDH1/CDKN1A/GADD45A	2.32193896115474
Organismal Systems	Excretory system	hsa04960	Aldosterone-regulated sodium reabsorption	4/343	38/9376	2.87739757557158	INSR/PIK3R1/PIK3CB/SFN	2.25963248334044
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	5/343	59/9376	2.31654889558729	UPP1/UCK2/CDA/CTPS1/NT5E	1.97670401449243
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	9/343	138/9376	1.78273545443022	FN1/PIK3R1/ITGA5/PIK3CB/PTK2/AKT3/PIP5K1B/BAIAP2/ITGB1	1.80502101777147
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	13/343	224/9376	1.58642232403165	HLA-G/PIK3R1/PIK3CB/IL1R1/AKT3/CREB3L2/CREB5/FOSL1/HLA-DRB5/CDKN1A/JAK1/SMAD3/PTEN	1.73098454889941
Metabolism	Lipid metabolism	hsa00592	alpha-Linolenic acid metabolism	3/343	26/9376	3.15407041937654	PLA2G4A/PLA2G5/PLA2G2A	2.14317413092553
Organismal Systems	Digestive system	hsa04977	Vitamin digestion and absorption	3/343	26/9376	3.15407041937654	APOB/APOA1/SLC19A3	2.14317413092553
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	8/343	119/9376	1.8376656785163	PTGS2/PIK3R1/PIK3CB/AKT3/CREB3L2/CCL20/CREB5/MMP14	1.79194948807244
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	7/343	99/9376	1.93279736136879	KRT19/DEFB1/KRT17/HLA-DRB5/KRT14/KRT18/CFH	1.81810022692386
Organismal Systems	Digestive system	hsa04975	Fat digestion and absorption	4/343	43/9376	2.54281646213303	APOB/APOA1/PLA2G5/PLA2G2A	1.97585264283823
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	10/343	163/9376	1.67701085692822	PIK3R1/JAK2/PIK3CB/AKT3/CREB3L2/CREB5/CDKN1A/YWHAQ/JAK1/SMAD3	1.69904778370409
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	9/343	142/9376	1.73251755430542	VEGFA/PIK3R1/PIK3CB/PTK2/IL1R1/AKT3/SDC4/CTSL/TXN	1.71389403361965
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	5/343	63/9376	2.16946642602619	PLA2G4A/PTGS2/PLA2G5/GGT5/PLA2G2A	1.81480482231504
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	5/343	63/9376	2.16946642602619	TCF7L2/BMP2/WNT7A/CDKN1A/GADD45A	1.81480482231504
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	8/343	125/9376	1.74945772594752	SGMS2/PIK3R1/CERS6/PIK3CB/AKT3/KNG1/BDKRB2/PTEN	1.64370736120694
Cellular Processes	Transport and catabolism	hsa04137	Mitophagy - animal	7/343	105/9376	1.822351797862	GABARAPL1/RRAS2/ULK1/CITED2/SMURF1/OPTN/BNIP3L	1.65122288223954
Metabolism	Lipid metabolism	hsa00591	Linoleic acid metabolism	3/343	30/9376	2.733527696793	PLA2G4A/PLA2G5/PLA2G2A	1.85308447227022
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	7/343	107/9376	1.78828914743467	FOXO1/PFKP/AKT3/CREB3L2/PRKAG2/CREB5/PDE3B	1.59800336110172
Organismal Systems	Digestive system	hsa04973	Carbohydrate digestion and absorption	4/343	48/9376	2.2779397473275	PIK3R1/PIK3CB/AKT3/HK2	1.72963084329985
Metabolism	Carbohydrate metabolism	hsa00030	Pentose phosphate pathway	3/343	31/9376	2.64534938399323	PFKP/ALDOB/PGM1	1.78799384772515
Metabolism	Glycan biosynthesis and metabolism	hsa00514	Other types of O-glycan biosynthesis	4/343	49/9376	2.23145118105551	GALNT15/GALNT2/GALNT3/GALNT6	1.68407312126615
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	7/343	109/9376	1.75547650252762	JAK2/IL1RAP/GATA3/IL1R1/HLA-DRB5/JAK1/SMAD3	1.54589973115674
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	11/343	196/9376	1.53412268697566	HLA-G/VEGFA/PTGS2/TCF7L2/PIK3R1/JAK2/PLCG2/PIK3CB/AKT3/CDKN1A/JAK1	1.47253088773702
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	5/343	69/9376	1.98081717158913	PLA2G4A/PIK3R1/PLCG2/PIK3CB/AKT3	1.59339863995918
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	9/343	154/9376	1.59751618643747	PLA2G4A/EGFR/PTGS2/CACNA2D3/PRKAG2/OXTR/PPP1R12B/CDKN1A/KCNJ2	1.45684775548518
Metabolism	Amino acid metabolism	hsa00360	Phenylalanine metabolism	2/343	16/9376	3.41690962099125	MAOA/MIF	1.88538119285336
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	4/343	51/9376	2.14394329160236	PLA2G4A/PLA2G5/PLA2G2A/LPCAT1	1.59617997024993
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	5/343	71/9376	1.9250195047838	PIK3R1/JAK2/PIK3CB/AKT3/PRLR	1.52453910625052
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	5/343	71/9376	1.9250195047838	EGFR/PLCG2/MET/F11R/PTPN11	1.52453910625052
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	4/343	52/9376	2.10271361291769	INSR/PLA2G4A/PTGS2/IGF1R	1.55374580267733
Metabolism	Metabolism of other amino acids	hsa00430	Taurine and hypotaurine metabolism	2/343	17/9376	3.21591493740353	BAAT/GGT5	1.78188435699249
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	7/343	115/9376	1.66388642413487	PIK3R1/JAK2/PIK3CB/AKT3/CREB3L2/CREB5/KCNJ2	1.39582334955253
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	11/343	205/9376	1.46677095925478	HLA-G/PIK3R1/ACTN1/PIK3CB/CREB3L2/ACTN4/CREB5/CDKN1A/YWHAQ/MDM2/JAK1	1.31670688035293
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	11/343	205/9376	1.46677095925478	MT-ATP8/PDK4/INSR/PIK3R1/PIK3CB/AKT3/GFPT1/MT-ND4L/AGT/SMAD3/PTEN	1.31670688035293
Metabolism	Carbohydrate metabolism	hsa00051	Fructose and mannose metabolism	3/343	35/9376	2.34302374010829	PFKP/ALDOB/HK2	1.55109257473991
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	5/343	75/9376	1.822351797862	PIK3R1/PIK3CB/AKT3/CDKN1A/MDM2	1.3932856008606
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	5/343	75/9376	1.822351797862	ALB/GPX3/TTR/CREB3L2/CREB5	1.3932856008606
Metabolism	Carbohydrate metabolism	hsa00040	Pentose and glucuronate interconversions	3/343	36/9376	2.2779397473275	UGP2/UGT2B7/CRPPA	1.49694168906997
Metabolism	Amino acid metabolism	hsa00250	Alanine, aspartate and glutamate metabolism	3/343	37/9376	2.21637380821054	GLUL/GFPT1/AGXT	1.44455614973384
Metabolism	Amino acid metabolism	hsa00350	Tyrosine metabolism	3/343	37/9376	2.21637380821054	MAOA/MIF/PNMT	1.44455614973384
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	9/343	166/9376	1.48203308862271	INSR/IRS2/KCNMA1/AKT3/KNG1/CREB3L2/CREB5/BDKRB2/PDE3B	1.22100592938512
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	5/343	78/9376	1.75226134409808	PTGS2/JAK2/HLA-DRB5/JAK1/ITGB1	1.29998388636215
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	6/343	100/9376	1.6401166180758	MME/ITGA5/IL1R1/ITGA6/HLA-DRB5/TFRC	1.25399390374236
Metabolism	Glycan biosynthesis and metabolism	hsa00541	Biosynthesis of various nucleotide sugars	2/343	20/9376	2.733527696793	UGP2/UAP1	1.51222832771566
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	10/343	193/9376	1.41633559419327	PIK3R1/JAK2/PLCG2/PIK3CB/PTK2/AKT3/CCL21/TIAM1/PARD3/CCL20	1.13879774235406
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	6/343	103/9376	1.59234623114156	SLC38A2/MME/COL17A1/COL12A1/SLC7A8/COL11A1	1.17787934217631
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	6/343	103/9376	1.59234623114156	SERPINE1/PIK3R1/PIK3CB/AKT3/KNG1/BDKRB2	1.17787934217631
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	6/343	104/9376	1.57703520968827	PLA2G4A/SGMS2/LPIN1/PLA2G5/PLA2G2A/LPCAT1	1.15305219040666
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	6/343	105/9376	1.56201582673886	PTGS2/PLCG2/IL1R1/CCL21/PPP1R13L/GADD45A	1.12848709725531
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	7/343	128/9376	1.49489795918367	ADK/GDA/PGM1/NT5E/PDE3B/ATIC/AMPD3	1.098533816043
Metabolism	Amino acid metabolism	hsa00310	Lysine degradation	4/343	63/9376	1.73557314082095	AASS/PLOD2/KMT2C/EZH2	1.14147927073315
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	7/343	130/9376	1.47189952904239	VEGFA/EGFR/PIK3R1/PIK3CB/AKT3/CREB3L2/CREB5	1.05574970470239
Organismal Systems	Endocrine system	hsa04614	Renin-angiotensin system	2/343	23/9376	2.37698060590696	MME/AGT	1.28834734679421
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	11/343	226/9376	1.33047808250987	PIK3R1/CRH/PIK3CB/RRAS2/AKT3/CREB3L2/TIAM1/OXTR/CREB5/PDE3B/AFDN	0.97994799297512
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	8/343	155/9376	1.41085300479639	EGFR/TCF7L2/CRH/WNT7A/CREB3L2/CREB5/CDKN1A/AGT	1.00503225205692
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	11/343	227/9376	1.32461694558251	MT-ATP8/VEGFA/EGFR/PIK3R1/PIK3CB/PTK2/AKT3/MET/MT-ND4L/PTPN11/PTEN	0.964748239944532
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	9/343	180/9376	1.3667638483965	HLA-G/PIK3R1/ITGA5/JAK2/PIK3CB/AKT3/HLA-DRB5/PTPN11/JAK1	0.968144060479982
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	10/343	205/9376	1.33342814477707	HLA-G/PIK3R1/PLCG2/PIK3CB/AKT3/HLA-DRB5/CDKN1A/GADD45A/MDM2/JAK1	0.940562225705326
Metabolism	Glycan biosynthesis and metabolism	hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	2/343	24/9376	2.2779397473275	NDST1/HS3ST2	1.22146335687805
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	8/343	158/9376	1.38406465660405	WEE1/SFN/CDKN1A/YWHAQ/GADD45A/CUL1/MDM2/SMAD3	0.94870508399144
Environmental Information Processing	Membrane transport	hsa02010	ABC transporters	3/343	45/9376	1.822351797862	ABCA8/DEFB1/ABCA6	1.07749807144013
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	4/343	67/9376	1.63195683390627	PFKP/ALDOB/HK2/PGM1	1.01155614789002
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	5/343	91/9376	1.50193829494121	PIK3R1/PLCG2/PIK3CB/AKT3/DAPP1	0.937555025965398
Organismal Systems	Endocrine system	hsa04924	Renin secretion	4/343	69/9376	1.58465373727131	KCNMA1/KCNJ2/PDE3B/AGT	0.949806443851085
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	6/343	116/9376	1.41389363627224	GLUL/SLC38A2/PLA2G4A/SLC38A1/SHANK2/HOMER1	0.874035240481792
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	7/343	140/9376	1.3667638483965	SERPINE1/RRAS2/AKT3/CDH1/PRKAG2/PDE3B/SMAD3	0.851971897880792
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	5/343	94/9376	1.45400409403883	PTGS2/LCN2/CCL20/FOSL1/S100A8	0.862024495548153
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	7/343	142/9376	1.34751365334866	PIK3R1/PLCG2/PIK3CB/IL1R1/AKT3/FOSL1/JAK1	0.813088469450255
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	3/343	49/9376	1.67358838579163	MAOA/CREB3L2/CREB5	0.921166923025274
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	5/343	95/9376	1.43869878778579	FLT1/VEGFA/CCL20/CTSL/HLA-DRB5	0.837428127328989
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	10/343	217/9376	1.25969018285392	VEGFA/EGFR/PIK3R1/JAK2/KLF5/PIK3CB/AKT3/UGT2B7/CREB3L2/CREB5	0.754185299091588
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	6/343	120/9376	1.3667638483965	PIK3R1/PLCG2/PIK3CB/AKT3/PTPN11/GAB1	0.787920072175612
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	3/343	50/9376	1.6401166180758	SAT1/CKB/MAOA	0.884327421129817
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	13/343	298/9376	1.19247852544661	IL1RL1/INHBA/BMP2/IL1RAP/INHA/IL1R1/CCL21/CCL20/PRLR/CLCF1/TNFRSF12A/INHBB/LEP	0.657978978703153
Organismal Systems	Immune system	hsa04611	Platelet activation	6/343	126/9376	1.30167985561572	PLA2G4A/PIK3R1/PLCG2/PIK3CB/AKT3/ITGB1	0.664320127484114
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	2/343	31/9376	1.76356625599549	GLUL/AGXT	0.829764049710229
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	3/343	55/9376	1.49101510734164	SGMS2/CERS6/HEXB	0.711642109506327
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	7/343	154/9376	1.24251258945136	TPM1/CACNA2D3/AKT3/CREB3L2/CREB5/ACTC1/AGT	0.59128761636668
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	7/343	155/9376	1.23449637919684	HLA-G/THBS1/ITGA5/CTSL/HLA-DRB5/ITGB1/TFRC	0.573627115615695
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	7/343	157/9376	1.21877031067204	INSR/IRS2/PIK3R1/PIK3CB/AKT3/PRKAG2/LEP	0.538657852537884
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	4/343	82/9376	1.33342814477707	UPP1/UGT2B7/UCK2/CDA	0.59091435614122
Organismal Systems	Environmental adaptation	hsa04710	Circadian rhythm	2/343	34/9376	1.60795746870177	PRKAG2/CUL1	0.692005296112826
Genetic Information Processing	Information processing in viruses	hsa03265	Virion - Ebolavirus, Lyssavirus and Morbillivirus	1/343	12/9376	2.2779397473275	NECTIN4	0.863151424641772
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	5/343	110/9376	1.24251258945136	PIK3R1/IGF1R/PIK3CB/AKT3/PDE3B	0.498541339939558
Organismal Systems	Nervous system	hsa04730	Long-term depression	3/343	60/9376	1.3667638483965	PLA2G4A/CRH/IGF1R	0.555346577113987
Genetic Information Processing	Replication and repair	hsa03450	Non-homologous end-joining	1/343	13/9376	2.10271361291769	RAD50	0.775253246346573
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	6/343	137/9376	1.19716541465387	PIK3R1/PIK3CB/AKT3/CTSL/GADD45A/CAPN2	0.452996899556546
Organismal Systems	Digestive system	hsa04978	Mineral absorption	3/343	61/9376	1.34435788366869	TF/SLC34A2/MT2A	0.525775337812087
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	2/343	37/9376	1.47758253880703	APOA1/KNG1	0.567173338312937
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	2/343	38/9376	1.43869878778579	NNMT/NT5E	0.528017104198635
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	4/343	89/9376	1.22855177383955	GLUL/SLC38A2/SLC38A1/GABARAPL1	0.422142006375502
Cellular Processes	Cell motility	hsa04814	Motor proteins	8/343	194/9376	1.1272279162033	TPM1/KIF21A/ACTG2/MYO1E/DNAH11/ACTC1/MYO5B/MYH9	0.348924390077353
Metabolism	Metabolism of cofactors and vitamins	hsa00670	One carbon pool by folate	2/343	39/9376	1.40180907527846	ATIC/MTHFD1L	0.48996500095569
Human Diseases	Immune disease	hsa05330	Allograft rejection	2/343	39/9376	1.40180907527846	HLA-G/HLA-DRB5	0.48996500095569
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	3/343	65/9376	1.26162816775062	CREB3L2/CREB5/AGT	0.412438983524462
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	3/343	65/9376	1.26162816775062	PIK3R1/PIK3CB/AKT3	0.412438983524462
Metabolism	Glycan biosynthesis and metabolism	hsa00604	Glycosphingolipid biosynthesis - ganglio series	1/343	15/9376	1.822351797862	HEXB	0.621096162956288
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	3/343	66/9376	1.24251258945136	GATA3/HLA-DRB5/SMAD3	0.385254845087848
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	4/343	93/9376	1.17571083733032	JAK2/GATA3/HLA-DRB5/JAK1	0.331827626392312
Metabolism	Amino acid metabolism	hsa00260	Glycine, serine and threonine metabolism	2/343	41/9376	1.33342814477707	MAOA/AGXT	0.416920947711081
Metabolism	Glycan biosynthesis and metabolism	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	1/343	16/9376	1.70845481049563	HEXB	0.552650940727824
Metabolism	Metabolism of cofactors and vitamins	hsa00830	Retinol metabolism	3/343	68/9376	1.20596810152632	UGT2B7/CYP3A5/RDH13	0.332156631950154
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	3/343	69/9376	1.18849030295348	MAOA/CREB3L2/CREB5	0.306214247742986
Metabolism	Lipid metabolism	hsa00120	Primary bile acid biosynthesis	1/343	17/9376	1.60795746870177	BAAT	0.488877025426699
Metabolism	Energy metabolism	hsa00910	Nitrogen metabolism	1/343	17/9376	1.60795746870177	GLUL	0.488877025426699
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	3/343	70/9376	1.17151187005414	PTGS2/UGT2B7/CYP3A5	0.280658610815393
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	3/343	70/9376	1.17151187005414	HLA-G/HLA-DRB5/DMD	0.280658610815393
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	2/343	44/9376	1.24251258945136	HEXB/MAN2A1	0.314188261483461
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	2/343	44/9376	1.24251258945136	HLA-G/HLA-DRB5	0.314188261483461
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	2/343	44/9376	1.24251258945136	CREB3L2/CREB5	0.314188261483461
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	4/343	98/9376	1.11572559052776	DAGLB/CREB3L2/CREB5/AGT	0.224404701951014
Metabolism	Lipid metabolism	hsa00061	Fatty acid biosynthesis	1/343	18/9376	1.51862649821834	ACSL3	0.429156927813561
Metabolism	Glycan biosynthesis and metabolism	hsa00511	Other glycan degradation	1/343	18/9376	1.51862649821834	HEXB	0.429156927813561
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	2/343	45/9376	1.21490119857467	HLA-G/HLA-DRB5	0.281577334197347
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	6/343	154/9376	1.06501079095831	UGP2/UGT2B7/RFK/CTPS1/RDH13/MTHFD1L	0.15850754680743
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	3/343	73/9376	1.12336754662726	MAOA/UGT2B7/CYP3A5	0.206189972556532
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	2/343	46/9376	1.18849030295348	CP/UGT2B7	0.249714522178404
Metabolism	Glycan biosynthesis and metabolism	hsa00531	Glycosaminoglycan degradation	1/343	19/9376	1.43869878778579	HEXB	0.372985211850582
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	6/343	157/9376	1.04466026629032	THBS1/PTGS2/JAK2/MFGE8/PTK2/PTPN11	0.109962832981378
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	3/343	75/9376	1.0934110787172	GLUL/PFKP/ALDOB	0.158263545207658
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	8/343	214/9376	1.02187951281981	HLA-G/PIK3R1/PLCG2/PIK3CB/PTK2/WEE1/AKT3/CUL1	0.0630908071554863
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	5/343	133/9376	1.02764199127556	HLA-G/PIK3R1/PLCG2/PIK3CB/PTPN11	0.0625612420928433
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	3/343	78/9376	1.05135680645885	ITGA5/SERPING1/ITGB1	0.0887497694455724
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	2/343	50/9376	1.0934110787172	THBS1/MET	0.12904832653033
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	9/343	248/9376	0.992006018997461	TCF7L2/ANXA2/PIK3CB/AHNAK/AKT3/S100A10/CYTH3/AHNAK2/TXN	-0.024860956270167
Metabolism	Amino acid metabolism	hsa00340	Histidine metabolism	1/343	22/9376	1.24251258945136	MAOA	0.221903238059077
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	14/343	388/9376	0.986324426677888	MT-ATP8/INSR/MME/IRS2/PTGS2/PIK3R1/SLC39A14/DKK1/PIK3CB/AKT3/WNT7A/ULK1/MT-ND4L/CAPN2	-0.0536100937109354
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	2/343	51/9376	1.07197164580118	PLCG2/TJP2	0.100424295764563
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	4/343	109/9376	1.00312943001578	PIK3R1/PIK3CB/AKT3/JAK1	0.00640362076634223
Metabolism	Amino acid metabolism	hsa00220	Arginine biosynthesis	1/343	23/9376	1.18849030295348	GLUL	0.176357590415446
Metabolism	Glycan biosynthesis and metabolism	hsa00515	Mannose type O-glycan biosynthesis	1/343	23/9376	1.18849030295348	CRPPA	0.176357590415446
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	3/343	82/9376	1.00007110858281	HLA-G/CTSL/HLA-DRB5	0.000126021402461284
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	2/343	53/9376	1.03151988558227	CLTB/BDKRB2	0.0448395678265364
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	3/343	83/9376	0.988022059081808	BAAT/AGXT/ACSL3	-0.0213579682855453
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	2/343	54/9376	1.01241766547889	HLA-G/HLA-DRB5	0.0178319558361591
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	5/343	142/9376	0.962509752391902	SMURF1/UBE2H/BIRC7/CUL1/MDM2	-0.0877170947191403
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	5/343	144/9376	0.949141561386459	FOXO1/TCF7L2/LPIN1/AKT3/PRKAG2	-0.119843108198658
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	6/343	173/9376	0.948044287905088	PIK3R1/JAK2/PIK3CB/AKT3/HLA-DRB5/JAK1	-0.134402805813729
Environmental Information Processing	Signal transduction	hsa04340	Hedgehog signaling pathway	2/343	56/9376	0.976259891711787	SMURF1/CUL1	-0.0347204580555929
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	3/343	86/9376	0.953556173299885	KCNMA1/CREB3L2/CREB5	-0.0843113527732709
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	4/343	116/9376	0.942595757514829	PFKP/ALDOB/HK2/AGXT	-0.12122276471098
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	3/343	87/9376	0.942595757514829	TPM1/CACNA2D3/ACTC1	-0.104817990218679
Metabolism	Lipid metabolism	hsa01040	Biosynthesis of unsaturated fatty acids	1/343	27/9376	1.01241766547889	BAAT	0.0125908761333658
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	3/343	89/9376	0.921413830379664	PDGFD/EGFR/LPAR1	-0.145151020968157
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	2/343	59/9376	0.926619558234916	GPX3/GGT5	-0.110175485550473
Metabolism	Glycan biosynthesis and metabolism	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	1/343	28/9376	0.976259891711787	ST3GAL6	-0.0245142749349268
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	4/343	122/9376	0.89623858911246	PIK3R1/PIK3CB/AKT3/PTPN11	-0.224785208098649
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	3/343	93/9376	0.881783127997743	PLA2G4A/EGFR/MMP14	-0.223251022145478
Environmental Information Processing	Signal transduction	hsa04330	Notch signaling pathway	2/343	62/9376	0.881783127997743	CTBP2/TLE1	-0.181980093932912
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	1/343	30/9376	0.911175898931001	ATIC	-0.0949500620952449
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	7/343	216/9376	0.885865457294029	APOB/APOA1/PIK3R1/JAK2/PIK3CB/PTK2/AKT3	-0.33068381168203
Metabolism	Carbohydrate metabolism	hsa00053	Ascorbate and aldarate metabolism	1/343	31/9376	0.881783127997743	UGT2B7	-0.128465748304688
Genetic Information Processing	Folding, sorting and degradation	hsa03060	Protein export	1/343	31/9376	0.881783127997743	IMMP2L	-0.128465748304688
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	2/343	65/9376	0.841085445167078	LPIN1/MGLL	-0.250517969934368
Cellular Processes	Transport and catabolism	hsa04136	Autophagy - other	1/343	32/9376	0.854227405247813	GABARAPL1	-0.160953769298827
Cellular Processes	Cell growth and death	hsa04215	Apoptosis - multiple species	1/343	32/9376	0.854227405247813	BIRC7	-0.160953769298827
Human Diseases	Immune disease	hsa05310	Asthma	1/343	32/9376	0.854227405247813	HLA-DRB5	-0.160953769298827
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	2/343	66/9376	0.82834172630091	UGT2B7/CYP3A5	-0.272695870311726
Metabolism	Global and overview maps	hsa01210	2-Oxocarboxylic acid metabolism	1/343	33/9376	0.82834172630091	AGXT	-0.192484263337724
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	8/343	254/9376	0.860953605289135	FLT1/VEGFA/PDGFD/EGFR/PLCG2/MET/OXTR/BDKRB2	-0.437772271742776
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	3/343	101/9376	0.811938919839506	TCF7L2/WNT7A/CREB3L2	-0.370270699958822
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	4/343	133/9376	0.822113593020452	MAOA/AKT3/CREB3L2/CREB5	-0.402604662635546
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	3/343	102/9376	0.803978734350883	KCNMA1/PLA2G5/PLA2G2A	-0.387870207205642
Human Diseases	Infectious disease: viral	hsa05162	Measles	4/343	136/9376	0.803978734350883	PIK3R1/PIK3CB/AKT3/JAK1	-0.448697190945044
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	5/343	168/9376	0.813549909759822	GLUL/PLA2G4A/JAK2/JAK1/CAPN2	-0.475172476023093
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	7/343	235/9376	0.814242292661746	MT-ATP8/MGLL/CREB3L2/PRKAG2/CREB5/MT-ND4L/ACSL3	-0.561953799647888
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	2/343	76/9376	0.719349393892895	EZR/KCNJ2	-0.478682994791879
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	4/343	144/9376	0.759313249109168	PIK3R1/PIK3CB/AKT3/ULK1	-0.567155601220398
Genetic Information Processing	Replication and repair	hsa03440	Homologous recombination	1/343	41/9376	0.666714072388537	RAD50	-0.416743118345454
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	2/343	79/9376	0.692032328302026	UGT2B7/CYP3A5	-0.535628840191131
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/343	42/9376	0.650839927807858	MAOA	-0.441908153485541
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	5/343	181/9376	0.75511814828536	JAK2/AKT3/KSR1/HLA-DRB5/JAK1	-0.648241326118756
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	3/343	115/9376	0.713094181772088	PLA2G4A/PTGS2/MAOA	-0.603220408862641
Metabolism	Lipid metabolism	hsa00071	Fatty acid degradation	1/343	43/9376	0.635704115533256	ACSL3	-0.466546088770371
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	4/343	149/9376	0.733832938736377	PTGS2/MGLL/DAGLB/MT-ND4L	-0.638166314951246
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	9/343	308/9376	0.798758093218735	GPX3/MT-ATP8/CLTB/ULK1/CREB3L2/CREB5/DNAH11/TGM2/MT-ND4L	-0.699769032369614
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	1/343	50/9376	0.546705539358601	HLA-DRB5	-0.626230768069156
Organismal Systems	Digestive system	hsa04976	Bile secretion	2/343	90/9376	0.607450599287334	UGT2B7/BAAT	-0.729151757351211
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	6/343	238/9376	0.689124629443614	RPS4Y1/EGFR/PIK3R1/PLCG2/PIK3CB/JAK1	-0.946598715304618
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	10/343	370/9376	0.738791269403514	CRH/LPAR1/ADM/THRB/KNG1/OXTR/BDKRB2/PRLR/AGT/LEP	-0.998939698143204
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	1/343	56/9376	0.488129945855893	MAN2A1	-0.748621806146031
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	1/343	57/9376	0.479566262595264	ACSL3	-0.767953470283739
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	3/343	138/9376	0.59424515147674	IGF1R/YWHAQ/CUL1	-0.935687818281209
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	2/343	100/9376	0.546705539358601	CCL21/CCL20	-0.888007707022508
Genetic Information Processing	Translation	hsa03015	mRNA surveillance pathway	2/343	103/9376	0.530782077047185	MSI2/ACIN1	-0.933038937987131
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	3/343	143/9376	0.573467348977553	ACTN1/ACTN4/HLA-DRB5	-1.00153372037668
Human Diseases	Substance dependence	hsa05034	Alcoholism	4/343	191/9376	0.572466533359791	CRH/MAOA/CREB3L2/CREB5	-1.16322549610898
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	4/343	195/9376	0.560723630111385	PIK3R1/PLCG2/PIK3CB/AKT3	-1.20788850107252
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	1/343	73/9376	0.374455848875754	ELL2	-1.04550130791614
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	6/343	275/9376	0.596406042936655	MT-ATP8/PIK3R1/PIK3CB/CREB3L2/CREB5/MT-ND4L	-1.3236803988369
Genetic Information Processing	Folding, sorting and degradation	hsa03018	RNA degradation	1/343	78/9376	0.350452268819616	PFKP	-1.122484347471
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	1/343	79/9376	0.346016164151013	CLTB	-1.13743303499425
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	5/343	250/9376	0.546705539358601	HEXB/CLTB/CTSL/AP3S1/RRAGC	-1.41555542054708
Genetic Information Processing	Chromosome	hsa03083	Polycomb repressive complex	1/343	83/9376	0.329340686360603	EZH2	-1.19585832397629
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	2/343	138/9376	0.396163434317827	MT-ATP8/MT-ND4L	-1.39247262428999
Human Diseases	Substance dependence	hsa05032	Morphine addiction	1/343	91/9376	0.300387658988242	PDE3B	-1.30678426642027
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/343	93/9376	0.293927709332581	KCNMA1	-1.33340831922106
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	3/343	187/9376	0.438533855100482	GABARAPL1/JAK1/TXN	-1.5112173989129
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	5/343	268/9376	0.509986510595709	MT-ATP8/SLC39A14/MAOA/MT-ND4L/TXN	-1.58591758568058
Genetic Information Processing	Translation	hsa03013	Nucleocytoplasmic transport	1/343	108/9376	0.253104416369722	ACIN1	-1.52123199052081
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	7/343	368/9376	0.519964507542147	GPX3/MT-ATP8/NRG2/ULK1/DNAH11/OPTN/MT-ND4L	-1.83062657530645
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	10/343	480/9376	0.569484936831876	GPX3/MT-ATP8/PTGS2/DKK1/WNT7A/ULK1/DNAH11/OPTN/MT-ND4L/CAPN2	-1.88681046406381
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/343	117/9376	0.233634845879744	MORF4L2	-1.62541151265797
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	2/343	174/9376	0.314198585838276	CUL1/CAPN2	-1.7792975432372
Genetic Information Processing	Translation	hsa03010	Ribosome	1/343	222/9376	0.123131878233919	RPS4Y1	-2.57645171628655
Genetic Information Processing	Transcription	hsa03040	Spliceosome	1/343	243/9376	0.112490851719877	ACIN1	-2.73140398982766