ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0045296	cadherin binding	51/616	334/18639	0.152694610778443	4.62025138035617	4.10418575702286e-20	3.6814546240495e-17
GO:0003779	actin binding	49/616	443/18639	0.110609480812641	3.34683459880977	1.1871065439989e-13	5.32417284983508e-11
GO:0098641	cadherin binding involved in cell-cell adhesion	10/616	18/18639	0.555555555555556	16.8100649350649	4.98399655149649e-11	1.49021496889745e-08
GO:0098632	cell-cell adhesion mediator activity	15/616	55/18639	0.272727272727273	8.25221369539551	1.81088627709325e-10	4.06091247638162e-08
GO:0008201	heparin binding	24/616	172/18639	0.13953488372093	4.22206282090003	2.54695634307115e-09	4.29016238899425e-07
GO:0098631	cell adhesion mediator activity	16/616	76/18639	0.210526315789474	6.37012987012987	2.86967383879214e-09	4.29016238899425e-07
GO:0005178	integrin binding	22/616	161/18639	0.136645962732919	4.1346495119787	1.73661113045125e-08	2.2253431200211e-06
GO:0005539	glycosaminoglycan binding	27/616	242/18639	0.111570247933884	3.3759056026618	3.55701591498189e-08	3.98830409467344e-06
GO:0005543	phospholipid binding	40/616	497/18639	0.0804828973843058	2.43526091614623	2.1660083491268e-07	2.15878832129638e-05
GO:0004866	endopeptidase inhibitor activity	20/616	161/18639	0.124223602484472	3.758772283617	3.76990864509583e-07	3.38160805465096e-05
GO:0005201	extracellular matrix structural constituent	20/616	168/18639	0.119047619047619	3.60215677179963	7.50941440515253e-07	6.12358611038347e-05
GO:0030414	peptidase inhibitor activity	20/616	169/18639	0.118343195266272	3.58084223468839	8.25920044783253e-07	6.17375233475481e-05
GO:0005520	insulin-like growth factor binding	7/616	19/18639	0.368421052631579	11.1477272727273	1.48321431140524e-06	0.00010034647532029
GO:1901681	sulfur compound binding	26/616	275/18639	0.0945454545454545	2.86076741440378	1.61735221296277e-06	0.00010034647532029
GO:0051015	actin filament binding	22/616	209/18639	0.105263157894737	3.18506493506493	1.75661034625419e-06	0.00010034647532029
GO:0031994	insulin-like growth factor I binding	6/616	13/18639	0.461538461538462	13.9652847152847	1.78990368464285e-06	0.00010034647532029
GO:0043394	proteoglycan binding	9/616	37/18639	0.243243243243243	7.36008248508249	2.40999842674981e-06	0.000127162858164387
GO:0004867	serine-type endopeptidase inhibitor activity	14/616	95/18639	0.147368421052632	4.45909090909091	2.77422478798979e-06	0.000138248868601491
GO:0061135	endopeptidase regulator activity	20/616	184/18639	0.108695652173913	3.28892574816488	3.14878625034633e-06	0.000148655856134771
GO:0001968	fibronectin binding	8/616	30/18639	0.266666666666667	8.06883116883117	4.18050094074699e-06	0.000187495467192503
GO:0005158	insulin receptor binding	7/616	23/18639	0.304347826086957	9.20899209486166	6.43004917154954e-06	0.000274654957470473
GO:0061134	peptidase regulator activity	21/616	226/18639	0.0929203539823009	2.81159493161706	2.08451287359856e-05	0.000849912748917231
GO:0004857	enzyme inhibitor activity	31/616	416/18639	0.0745192307692308	2.25481159465534	2.33294199447737e-05	0.000909847377846174
GO:0043560	insulin receptor substrate binding	5/616	13/18639	0.384615384615385	11.6377372627373	4.00442183495099e-05	0.00149665266081293
GO:0019838	growth factor binding	15/616	136/18639	0.110294117647059	3.33729230328495	4.45168520727553e-05	0.00159726465237046
GO:0051020	GTPase binding	25/616	315/18639	0.0793650793650794	2.40143784786642	5.17578761587172e-05	0.00178564672747574
GO:0050840	extracellular matrix binding	10/616	67/18639	0.149253731343284	4.5161368482264	6.55953046612075e-05	0.002179221788189
GO:0140272	exogenous protein binding	11/616	82/18639	0.134146341463415	4.05901567944251	7.82546616943948e-05	0.00250694398356686
GO:0035591	signaling adaptor activity	14/616	129/18639	0.108527131782946	3.2838266384778	9.45835720514716e-05	0.00292556772862655
GO:0019209	kinase activator activity	15/616	148/18639	0.101351351351351	3.06670103545104	0.000117654451750447	0.00351786810733837
GO:0055102	lipase inhibitor activity	5/616	16/18639	0.3125	9.45566152597403	0.000125142052220354	0.00362104583360185
GO:0141003	histone H2AX kinase activity	26/616	354/18639	0.0734463276836158	2.22234756768655	0.000132293126243345	0.00370834169500875
GO:0140996	histone H3 kinase activity	26/616	357/18639	0.0728291316526611	2.20367237804213	0.00015141453171952	0.00411572227128513
GO:0035173	histone kinase activity	26/616	360/18639	0.0722222222222222	2.18530844155844	0.000172960380084867	0.004563101792239
GO:0030295	protein kinase activator activity	14/616	139/18639	0.100719424460432	3.047580117724	0.000210085309196238	0.00538418635282931
GO:0001618	virus receptor activity	10/616	81/18639	0.123456790123457	3.73556998556999	0.000328530966525665	0.00818589658259781
GO:1990247	N6-methyladenosine-containing RNA reader activity	4/616	12/18639	0.333333333333333	10.086038961039	0.000473145952064679	0.0114705924054599
GO:0031267	small GTPase binding	21/616	283/18639	0.0742049469964664	2.24530195952457	0.000497700330837941	0.0116910693932825
GO:0010314	phosphatidylinositol-5-phosphate binding	5/616	21/18639	0.238095238095238	7.20431354359926	0.000508307364925327	0.0116910693932825
GO:0005518	collagen binding	9/616	72/18639	0.125	3.78226461038961	0.000589975257792452	0.0132301951559957
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	4/616	13/18639	0.307692307692308	9.31018981018981	0.000665635611493645	0.0145628083782878
GO:0001786	phosphatidylserine binding	8/616	59/18639	0.135593220338983	4.10279550957517	0.000682141337726944	0.0145685899985969
GO:0004713	protein tyrosine kinase activity	13/616	140/18639	0.0928571428571429	2.80968228200371	0.000763486519340268	0.015926683903447
GO:0005161	platelet-derived growth factor receptor binding	4/616	14/18639	0.285714285714286	8.64517625231911	0.000907650072056264	0.0185036844235106
GO:0019199	transmembrane receptor protein kinase activity	9/616	78/18639	0.115384615384615	3.49132117882118	0.00106124583533658	0.0211541669843759
GO:0005010	insulin-like growth factor receptor activity	7/616	51/18639	0.137254901960784	4.15307486631016	0.00136266293892613	0.0265719273090595
GO:0043548	phosphatidylinositol 3-kinase binding	5/616	26/18639	0.192307692307692	5.81886863136863	0.00143348362402354	0.0269950598489699
GO:0005179	hormone activity	12/616	132/18639	0.0909090909090909	2.75073789846517	0.00144455169760374	0.0269950598489699
GO:0004725	protein tyrosine phosphatase activity	10/616	98/18639	0.102040816326531	3.08756294725682	0.0014859701277832	0.0272023511147252
GO:0030159	signaling receptor complex adaptor activity	7/616	52/18639	0.134615384615385	4.07320804195804	0.00153054343910256	0.0274579492975
GO:0005544	calcium-dependent phospholipid binding	7/616	53/18639	0.132075471698113	3.9963550600343	0.0017141033522641	0.0296287880808196
GO:1990782	protein tyrosine kinase binding	11/616	117/18639	0.094017094017094	2.84478021978022	0.00171761090323592	0.0296287880808196
GO:0002020	protease binding	12/616	136/18639	0.0882352941176471	2.66983384262796	0.00186434742147703	0.0315532006993377
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	6/616	41/18639	0.146341463414634	4.42801710484637	0.00213475057299598	0.0354605789625444
GO:0003712	transcription coregulator activity	29/616	495/18639	0.0585858585858586	1.77269775678867	0.00219277950621976	0.0357622403105295
GO:0070064	proline-rich region binding	4/616	18/18639	0.222222222222222	6.72402597402597	0.0024977887376001	0.0400092231719159
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	9/616	89/18639	0.101123595505618	3.05980957245002	0.00268705079130657	0.0415566303414137
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	9/616	89/18639	0.101123595505618	3.05980957245002	0.00268705079130657	0.0415566303414137
GO:0008083	growth factor activity	13/616	162/18639	0.0802469135802469	2.42812049062049	0.00286132594880835	0.0433597585987329
GO:0140793	histone H2AXY142 phosphatase activity	9/616	90/18639	0.1	3.02581168831169	0.00290031830091859	0.0433597585987329
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	4/616	19/18639	0.210526315789474	6.37012987012987	0.00308204900910867	0.0453212780519751
GO:0070325	lipoprotein particle receptor binding	5/616	31/18639	0.161290322580645	4.88034143276079	0.00323218643385372	0.0467624392123675
GO:0019207	kinase regulator activity	19/616	287/18639	0.0662020905923345	2.00315059504955	0.00333356943833511	0.047463679145819
GO:1901981	phosphatidylinositol phosphate binding	14/616	185/18639	0.0756756756756757	2.28980343980344	0.00343644425387617	0.0481639139957331
GO:0004714	transmembrane receptor protein tyrosine kinase activity	7/616	60/18639	0.116666666666667	3.53011363636364	0.00352243733501474	0.0486096352232034
GO:0004679	AMP-activated protein kinase activity	17/616	248/18639	0.0685483870967742	2.07414510892333	0.00376607183720387	0.0511843399692708
GO:0005085	guanyl-nucleotide exchange factor activity	16/616	230/18639	0.0695652173913043	2.10491247882552	0.00422099576819806	0.0529873615447071
GO:0051428	peptide hormone receptor binding	4/616	21/18639	0.19047619047619	5.76345083487941	0.00451652385259245	0.0529873615447071
GO:0046332	SMAD binding	8/616	79/18639	0.10126582278481	3.06411310208779	0.00451719358053892	0.0529873615447071
GO:0032266	phosphatidylinositol-3-phosphate binding	6/616	48/18639	0.125	3.78226461038961	0.00479650543134199	0.0529873615447071
GO:0035401	histone H3Y41 kinase activity	10/616	115/18639	0.0869565217391304	2.6311405985319	0.00481144640432434	0.0529873615447071
GO:0140801	histone H2AXY142 kinase activity	10/616	115/18639	0.0869565217391304	2.6311405985319	0.00481144640432434	0.0529873615447071
GO:0003953	NAD+ nucleosidase activity	3/616	11/18639	0.272727272727273	8.25221369539551	0.00485997901020088	0.0529873615447071
GO:0016176	superoxide-generating NADPH oxidase activator activity	3/616	11/18639	0.272727272727273	8.25221369539551	0.00485997901020088	0.0529873615447071
GO:0045294	alpha-catenin binding	3/616	11/18639	0.272727272727273	8.25221369539551	0.00485997901020088	0.0529873615447071
GO:0097493	structural molecule activity conferring elasticity	3/616	11/18639	0.272727272727273	8.25221369539551	0.00485997901020088	0.0529873615447071
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	5/616	34/18639	0.147058823529412	4.4497230710466	0.00488015206207506	0.0529873615447071
GO:0051427	hormone receptor binding	5/616	34/18639	0.147058823529412	4.4497230710466	0.00488015206207506	0.0529873615447071
GO:0003713	transcription coactivator activity	17/616	256/18639	0.06640625	2.00932807426948	0.00516875078007211	0.0529873615447071
GO:0015101	organic cation transmembrane transporter activity	8/616	81/18639	0.0987654320987654	2.98845598845599	0.00525970480129135	0.0529873615447071
GO:0005004	GPI-linked ephrin receptor activity	6/616	49/18639	0.122448979591837	3.70507553670819	0.00531645768007095	0.0529873615447071
GO:0005008	hepatocyte growth factor receptor activity	6/616	49/18639	0.122448979591837	3.70507553670819	0.00531645768007095	0.0529873615447071
GO:0005009	insulin receptor activity	6/616	49/18639	0.122448979591837	3.70507553670819	0.00531645768007095	0.0529873615447071
GO:0005011	macrophage colony-stimulating factor receptor activity	6/616	49/18639	0.122448979591837	3.70507553670819	0.00531645768007095	0.0529873615447071
GO:0005018	platelet-derived growth factor alpha-receptor activity	6/616	49/18639	0.122448979591837	3.70507553670819	0.00531645768007095	0.0529873615447071
GO:0005020	stem cell factor receptor activity	6/616	49/18639	0.122448979591837	3.70507553670819	0.00531645768007095	0.0529873615447071
GO:0008288	boss receptor activity	6/616	49/18639	0.122448979591837	3.70507553670819	0.00531645768007095	0.0529873615447071
GO:0036332	placental growth factor receptor activity	6/616	49/18639	0.122448979591837	3.70507553670819	0.00531645768007095	0.0529873615447071
GO:0038062	protein tyrosine kinase collagen receptor activity	6/616	49/18639	0.122448979591837	3.70507553670819	0.00531645768007095	0.0529873615447071
GO:0060175	brain-derived neurotrophic factor receptor activity	6/616	49/18639	0.122448979591837	3.70507553670819	0.00531645768007095	0.0529873615447071
GO:0140517	protein-RNA adaptor activity	4/616	22/18639	0.181818181818182	5.50147579693034	0.00537795957282656	0.0530113157892904
GO:0005006	epidermal growth factor receptor activity	6/616	50/18639	0.12	3.63097402597403	0.00587649524935941	0.0539186121746242
GO:0005007	fibroblast growth factor receptor activity	6/616	50/18639	0.12	3.63097402597403	0.00587649524935941	0.0539186121746242
GO:0005017	platelet-derived growth factor receptor activity	6/616	50/18639	0.12	3.63097402597403	0.00587649524935941	0.0539186121746242
GO:0005019	platelet-derived growth factor beta-receptor activity	6/616	50/18639	0.12	3.63097402597403	0.00587649524935941	0.0539186121746242
GO:0030165	PDZ domain binding	8/616	83/18639	0.0963855421686747	2.91644500078235	0.00609198247554147	0.0539186121746242
GO:0004869	cysteine-type endopeptidase inhibitor activity	5/616	36/18639	0.138888888888889	4.20251623376623	0.00626399493417614	0.0539186121746242
GO:0005078	MAP-kinase scaffold activity	3/616	12/18639	0.25	7.56452922077922	0.00632225669624628	0.0539186121746242
GO:0005527	macrolide binding	3/616	12/18639	0.25	7.56452922077922	0.00632225669624628	0.0539186121746242
GO:0035259	nuclear glucocorticoid receptor binding	3/616	12/18639	0.25	7.56452922077922	0.00632225669624628	0.0539186121746242
GO:0045295	gamma-catenin binding	3/616	12/18639	0.25	7.56452922077922	0.00632225669624628	0.0539186121746242
GO:0005021	vascular endothelial growth factor receptor activity	6/616	51/18639	0.117647058823529	3.55977845683728	0.00647833955741719	0.0539186121746242
GO:0005030	neurotrophin receptor activity	6/616	51/18639	0.117647058823529	3.55977845683728	0.00647833955741719	0.0539186121746242
GO:0030695	GTPase regulator activity	27/616	489/18639	0.0552147239263804	1.67069357023345	0.00670350048717362	0.0539186121746242
GO:0060589	nucleoside-triphosphatase regulator activity	27/616	490/18639	0.0551020408163265	1.66728399151869	0.00688042154785628	0.0539186121746242
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	16/616	243/18639	0.065843621399177	1.99230399230399	0.00709120156657577	0.0539186121746242
GO:0070300	phosphatidic acid binding	4/616	24/18639	0.166666666666667	5.04301948051948	0.0074155136740011	0.0539186121746242
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	8/616	86/18639	0.0930232558139535	2.81470854726669	0.007523187697092	0.0539186121746242
GO:0016209	antioxidant activity	8/616	86/18639	0.0930232558139535	2.81470854726669	0.007523187697092	0.0539186121746242
GO:0004676	3-phosphoinositide-dependent protein kinase activity	16/616	245/18639	0.0653061224489796	1.97604028624437	0.0076467825046049	0.0539186121746242
GO:0004711	ribosomal protein S6 kinase activity	16/616	245/18639	0.0653061224489796	1.97604028624437	0.0076467825046049	0.0539186121746242
GO:0035175	histone H3S10 kinase activity	16/616	245/18639	0.0653061224489796	1.97604028624437	0.0076467825046049	0.0539186121746242
GO:0035979	histone H2AXS139 kinase activity	16/616	245/18639	0.0653061224489796	1.97604028624437	0.0076467825046049	0.0539186121746242
GO:0044022	histone H3S28 kinase activity	16/616	245/18639	0.0653061224489796	1.97604028624437	0.0076467825046049	0.0539186121746242
GO:0044023	histone H4S1 kinase activity	16/616	245/18639	0.0653061224489796	1.97604028624437	0.0076467825046049	0.0539186121746242
GO:0044024	histone H2AS1 kinase activity	16/616	245/18639	0.0653061224489796	1.97604028624437	0.0076467825046049	0.0539186121746242
GO:0044025	histone H2BS14 kinase activity	16/616	245/18639	0.0653061224489796	1.97604028624437	0.0076467825046049	0.0539186121746242
GO:0072354	histone H3T3 kinase activity	16/616	245/18639	0.0653061224489796	1.97604028624437	0.0076467825046049	0.0539186121746242
GO:0072371	histone H2AS121 kinase activity	16/616	245/18639	0.0653061224489796	1.97604028624437	0.0076467825046049	0.0539186121746242
GO:0072518	Rho-dependent protein serine/threonine kinase activity	16/616	245/18639	0.0653061224489796	1.97604028624437	0.0076467825046049	0.0539186121746242
GO:0140823	histone H2BS36 kinase activity	16/616	245/18639	0.0653061224489796	1.97604028624437	0.0076467825046049	0.0539186121746242
GO:0140855	histone H3S57 kinase activity	16/616	245/18639	0.0653061224489796	1.97604028624437	0.0076467825046049	0.0539186121746242
GO:0140995	histone H2A kinase activity	16/616	245/18639	0.0653061224489796	1.97604028624437	0.0076467825046049	0.0539186121746242
GO:0140997	histone H4 kinase activity	16/616	245/18639	0.0653061224489796	1.97604028624437	0.0076467825046049	0.0539186121746242
GO:0140998	histone H2B kinase activity	16/616	245/18639	0.0653061224489796	1.97604028624437	0.0076467825046049	0.0539186121746242
GO:1990244	histone H2AT120 kinase activity	16/616	245/18639	0.0653061224489796	1.97604028624437	0.0076467825046049	0.0539186121746242
GO:0005003	ephrin receptor activity	6/616	53/18639	0.113207547169811	3.42544719431512	0.00781429161951075	0.0539186121746242
GO:0005005	transmembrane-ephrin receptor activity	6/616	53/18639	0.113207547169811	3.42544719431512	0.00781429161951075	0.0539186121746242
GO:0017046	peptide hormone binding	6/616	53/18639	0.113207547169811	3.42544719431512	0.00781429161951075	0.0539186121746242
GO:0038064	collagen receptor activity	6/616	53/18639	0.113207547169811	3.42544719431512	0.00781429161951075	0.0539186121746242
GO:0004677	DNA-dependent protein kinase activity	16/616	246/18639	0.0650406504065041	1.96800760215394	0.00793737170979297	0.053938048664275
GO:0140857	histone H3T45 kinase activity	16/616	246/18639	0.0650406504065041	1.96800760215394	0.00793737170979297	0.053938048664275
GO:0003714	transcription corepressor activity	14/616	204/18639	0.0686274509803922	2.07653743315508	0.00804529424916726	0.0542603679812258
GO:0035402	histone H3T11 kinase activity	16/616	247/18639	0.0647773279352227	1.96003996003996	0.00823673546102862	0.0547285311743902
GO:0035403	histone H3T6 kinase activity	16/616	247/18639	0.0647773279352227	1.96003996003996	0.00823673546102862	0.0547285311743902
GO:0042974	nuclear retinoic acid receptor binding	4/616	25/18639	0.16	4.8412987012987	0.00860136336649119	0.0567310510275191
GO:0005160	transforming growth factor beta receptor binding	4/616	26/18639	0.153846153846154	4.65509490509491	0.00990461422875805	0.0647319944151874
GO:0044548	S100 protein binding	3/616	14/18639	0.214285714285714	6.48388218923933	0.00995876837156729	0.0647319944151874
GO:0072341	modified amino acid binding	8/616	91/18639	0.0879120879120879	2.6600542314828	0.010451773739433	0.0674477772969165
GO:0004222	metalloendopeptidase activity	9/616	110/18639	0.0818181818181818	2.47566410861865	0.0107077526363285	0.0686061008199046
GO:0019887	protein kinase regulator activity	16/616	255/18639	0.0627450980392157	1.89854851031322	0.0109698019452128	0.0697866123748644
GO:1902936	phosphatidylinositol bisphosphate binding	9/616	111/18639	0.0810810810810811	2.45336082836083	0.0113226852262368	0.0715242862530595
GO:0030246	carbohydrate binding	17/616	280/18639	0.0607142857142857	1.83709995361781	0.0120917100055931	0.075666146241967
GO:0051371	muscle alpha-actinin binding	3/616	15/18639	0.2	6.05162337662338	0.0121470736441954	0.075666146241967
GO:0042562	hormone binding	8/616	94/18639	0.0851063829787234	2.57515888366952	0.0125717463523519	0.0777714239866183
GO:0045499	chemorepellent activity	4/616	28/18639	0.142857142857143	4.32258812615955	0.0128796068371641	0.0791301872118918
GO:0045309	protein phosphorylated amino acid binding	6/616	59/18639	0.101694915254237	3.07709663218138	0.0130004895182282	0.079329517672454
GO:0035091	phosphatidylinositol binding	17/616	284/18639	0.0598591549295775	1.81122530638376	0.0137486535599181	0.0833279881300441
GO:0001221	transcription coregulator binding	9/616	115/18639	0.0782608695652174	2.36802653867871	0.0140493076758559	0.0845787180217632
GO:0001223	transcription coactivator binding	5/616	44/18639	0.113636363636364	3.43842237308146	0.014551953009559	0.0849757990598944
GO:0043236	laminin binding	4/616	29/18639	0.137931034482759	4.17353336318854	0.0145587296484098	0.0849757990598944
GO:0005159	insulin-like growth factor receptor binding	3/616	16/18639	0.1875	5.67339691558442	0.0145889331719328	0.0849757990598944
GO:0022858	alanine transmembrane transporter activity	3/616	16/18639	0.1875	5.67339691558442	0.0145889331719328	0.0849757990598944
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	3/616	16/18639	0.1875	5.67339691558442	0.0145889331719328	0.0849757990598944
GO:0044325	transmembrane transporter binding	10/616	136/18639	0.0735294117647059	2.2248615355233	0.0149159460135588	0.0863200230591112
GO:0033612	receptor serine/threonine kinase binding	4/616	30/18639	0.133333333333333	4.03441558441558	0.0163700071219501	0.0941275409512132
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/616	17/18639	0.176470588235294	5.33966768525592	0.0172877704066611	0.0969195628423436
GO:0019198	transmembrane receptor protein phosphatase activity	3/616	17/18639	0.176470588235294	5.33966768525592	0.0172877704066611	0.0969195628423436
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	3/616	17/18639	0.176470588235294	5.33966768525592	0.0172877704066611	0.0969195628423436
GO:0046965	nuclear retinoid X receptor binding	3/616	17/18639	0.176470588235294	5.33966768525592	0.0172877704066611	0.0969195628423436
GO:0070273	phosphatidylinositol-4-phosphate binding	4/616	31/18639	0.129032258064516	3.90427314620863	0.018316350927594	0.101581750777595
GO:0042578	phosphoric ester hydrolase activity	20/616	363/18639	0.0550964187327824	1.66711387785768	0.0183458680334117	0.101581750777595
GO:0001784	phosphotyrosine residue binding	5/616	47/18639	0.106382978723404	3.2189486045869	0.0189691932045679	0.10438875033434
GO:0016791	phosphatase activity	16/616	273/18639	0.0586080586080586	1.7733694876552	0.0197226982369047	0.10787353852746
GO:0005126	cytokine receptor binding	16/616	275/18639	0.0581818181818182	1.76047225501771	0.0209544950419274	0.113916254864296
GO:0019239	deaminase activity	4/616	33/18639	0.121212121212121	3.6676505312869	0.0226243195731491	0.121521045850986
GO:0030296	protein tyrosine kinase activator activity	4/616	33/18639	0.121212121212121	3.6676505312869	0.0226243195731491	0.121521045850986
GO:0016500	protein-hormone receptor activity	6/616	67/18639	0.0895522388059701	2.70968210893584	0.0231279854727408	0.123486922434812
GO:0043395	heparan sulfate proteoglycan binding	3/616	19/18639	0.157894736842105	4.7775974025974	0.0234639638151041	0.124539500249399
GO:1990841	promoter-specific chromatin binding	6/616	68/18639	0.0882352941176471	2.66983384262796	0.024683284833365	0.130240626444285
GO:0008376	acetylgalactosaminyltransferase activity	4/616	34/18639	0.117647058823529	3.55977845683728	0.0249902085746256	0.131088988838826
GO:0097110	scaffold protein binding	6/616	70/18639	0.0857142857142857	2.59355287569573	0.0279998176427598	0.146022304799741
GO:0004674	protein serine/threonine kinase activity	22/616	433/18639	0.0508083140877598	1.53736390630155	0.0311253498934431	0.160617622140997
GO:0004721	phosphoprotein phosphatase activity	11/616	175/18639	0.0628571428571429	1.9019387755102	0.0311565955992569	0.160617622140997
GO:0005200	structural constituent of cytoskeleton	8/616	112/18639	0.0714285714285714	2.16129406307978	0.0323090613385421	0.165607017260985
GO:0042805	actinin binding	4/616	37/18639	0.108108108108108	3.27114777114777	0.0329546744138487	0.167956494029672
GO:0051219	phosphoprotein binding	7/616	93/18639	0.0752688172043011	2.2774926686217	0.0343328221477852	0.173991759698098
GO:0008093	cytoskeletal anchor activity	3/616	22/18639	0.136363636363636	4.12610684769776	0.0346750578077313	0.1747389149075
GO:0000146	microfilament motor activity	4/616	38/18639	0.105263157894737	3.18506493506493	0.0359020255591092	0.179911267745927
GO:0005096	GTPase activator activity	15/616	271/18639	0.0553505535055351	1.67480351751569	0.0363021690524485	0.180905809111368
GO:0140789	histone phosphatase activity	9/616	136/18639	0.0661764705882353	2.00237538197097	0.0367489745975705	0.182120608917242
GO:0099186	structural constituent of postsynapse	3/616	23/18639	0.130434782608696	3.94671089779785	0.0389249231723541	0.19114787056564
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	4/616	39/18639	0.102564102564103	3.1033966033966	0.0389967227575387	0.19114787056564
GO:0017022	myosin binding	6/616	76/18639	0.0789473684210526	2.3887987012987	0.0396649183944882	0.19336647717313
GO:0004862	cAMP-dependent protein kinase inhibitor activity	2/616	10/18639	0.2	6.05162337662338	0.0411575476540983	0.196374043860246
GO:0005131	growth hormone receptor binding	2/616	10/18639	0.2	6.05162337662338	0.0411575476540983	0.196374043860246
GO:0015187	glycine transmembrane transporter activity	2/616	10/18639	0.2	6.05162337662338	0.0411575476540983	0.196374043860246
GO:0042975	peroxisome proliferator activated receptor binding	2/616	10/18639	0.2	6.05162337662338	0.0411575476540983	0.196374043860246
GO:0030215	semaphorin receptor binding	3/616	24/18639	0.125	3.78226461038961	0.0434262673864045	0.202882092945859
GO:0048027	mRNA 5'-UTR binding	3/616	24/18639	0.125	3.78226461038961	0.0434262673864045	0.202882092945859
GO:0050431	transforming growth factor beta binding	3/616	24/18639	0.125	3.78226461038961	0.0434262673864045	0.202882092945859
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	3/616	24/18639	0.125	3.78226461038961	0.0434262673864045	0.202882092945859
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	5/616	59/18639	0.0847457627118644	2.56424719348448	0.0450248956946434	0.209260784653342
GO:0120020	cholesterol transfer activity	3/616	25/18639	0.12	3.63097402597403	0.0481751179345745	0.217505594066058
GO:0008307	structural constituent of muscle	4/616	42/18639	0.0952380952380952	2.8817254174397	0.049165918858831	0.217505594066058
GO:0005536	D-glucose binding	2/616	11/18639	0.181818181818182	5.50147579693034	0.0492236740194089	0.217505594066058
GO:0019206	nucleoside kinase activity	2/616	11/18639	0.181818181818182	5.50147579693034	0.0492236740194089	0.217505594066058
GO:0019215	intermediate filament binding	2/616	11/18639	0.181818181818182	5.50147579693034	0.0492236740194089	0.217505594066058
GO:0031731	CCR6 chemokine receptor binding	2/616	11/18639	0.181818181818182	5.50147579693034	0.0492236740194089	0.217505594066058
GO:0043522	leucine zipper domain binding	2/616	11/18639	0.181818181818182	5.50147579693034	0.0492236740194089	0.217505594066058
GO:0047676	arachidonate-CoA ligase activity	2/616	11/18639	0.181818181818182	5.50147579693034	0.0492236740194089	0.217505594066058
GO:0048185	activin binding	2/616	11/18639	0.181818181818182	5.50147579693034	0.0492236740194089	0.217505594066058
GO:0070697	activin receptor binding	2/616	11/18639	0.181818181818182	5.50147579693034	0.0492236740194089	0.217505594066058
GO:0019903	protein phosphatase binding	9/616	144/18639	0.0625	1.89113230519481	0.0497775588083111	0.218874854171839
GO:0052742	phosphatidylinositol kinase activity	3/616	26/18639	0.115384615384615	3.49132117882118	0.053166922765768	0.231508396703368
GO:0070412	R-SMAD binding	3/616	26/18639	0.115384615384615	3.49132117882118	0.053166922765768	0.231508396703368
GO:0015179	L-amino acid transmembrane transporter activity	5/616	62/18639	0.0806451612903226	2.44017071638039	0.0537774692997853	0.23303570029907
GO:0106310	protein serine kinase activity	18/616	361/18639	0.0498614958448753	1.50871496924129	0.0554015285744507	0.238919091977319
GO:0004859	phospholipase inhibitor activity	2/616	12/18639	0.166666666666667	5.04301948051948	0.0578039574840414	0.241163487735745
GO:0008603	cAMP-dependent protein kinase regulator activity	2/616	12/18639	0.166666666666667	5.04301948051948	0.0578039574840414	0.241163487735745
GO:0015132	prostaglandin transmembrane transporter activity	2/616	12/18639	0.166666666666667	5.04301948051948	0.0578039574840414	0.241163487735745
GO:0017166	vinculin binding	2/616	12/18639	0.166666666666667	5.04301948051948	0.0578039574840414	0.241163487735745
GO:0035014	phosphatidylinositol 3-kinase regulator activity	2/616	12/18639	0.166666666666667	5.04301948051948	0.0578039574840414	0.241163487735745
GO:0035497	cAMP response element binding	2/616	12/18639	0.166666666666667	5.04301948051948	0.0578039574840414	0.241163487735745
GO:0070410	co-SMAD binding	2/616	12/18639	0.166666666666667	5.04301948051948	0.0578039574840414	0.241163487735745
GO:0004715	non-membrane spanning protein tyrosine kinase activity	4/616	45/18639	0.0888888888888889	2.68961038961039	0.0606542554033366	0.251883643966634
GO:0051393	alpha-actinin binding	3/616	28/18639	0.107142857142857	3.24194109461967	0.0638586519270401	0.261558040084726
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	3/616	28/18639	0.107142857142857	3.24194109461967	0.0638586519270401	0.261558040084726
GO:0097718	disordered domain specific binding	3/616	28/18639	0.107142857142857	3.24194109461967	0.0638586519270401	0.261558040084726
GO:0030291	protein serine/threonine kinase inhibitor activity	4/616	46/18639	0.0869565217391304	2.6311405985319	0.0647727342767094	0.261875913553206
GO:0016298	lipase activity	8/616	130/18639	0.0615384615384615	1.86203796203796	0.0667696880852916	0.261875913553206
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	8/616	130/18639	0.0615384615384615	1.86203796203796	0.0667696880852916	0.261875913553206
GO:0005172	vascular endothelial growth factor receptor binding	2/616	13/18639	0.153846153846154	4.65509490509491	0.0668557237499267	0.261875913553206
GO:0008035	high-density lipoprotein particle binding	2/616	13/18639	0.153846153846154	4.65509490509491	0.0668557237499267	0.261875913553206
GO:0008253	5'-nucleotidase activity	2/616	13/18639	0.153846153846154	4.65509490509491	0.0668557237499267	0.261875913553206
GO:0039706	co-receptor binding	2/616	13/18639	0.153846153846154	4.65509490509491	0.0668557237499267	0.261875913553206
GO:0045159	myosin II binding	2/616	13/18639	0.153846153846154	4.65509490509491	0.0668557237499267	0.261875913553206
GO:0061459	L-arginine transmembrane transporter activity	2/616	13/18639	0.153846153846154	4.65509490509491	0.0668557237499267	0.261875913553206
GO:0071714	icosanoid transmembrane transporter activity	2/616	13/18639	0.153846153846154	4.65509490509491	0.0668557237499267	0.261875913553206
GO:0043495	protein-membrane adaptor activity	4/616	47/18639	0.0851063829787234	2.57515888366952	0.0690335287950481	0.266626884171128
GO:0003785	actin monomer binding	3/616	29/18639	0.103448275862069	3.1301500223914	0.0695471044976513	0.266626884171128
GO:0004629	phospholipase C activity	3/616	29/18639	0.103448275862069	3.1301500223914	0.0695471044976513	0.266626884171128
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	3/616	29/18639	0.103448275862069	3.1301500223914	0.0695471044976513	0.266626884171128
GO:0004620	phospholipase activity	7/616	109/18639	0.0642201834862385	1.94318181818182	0.0695548393489898	0.266626884171128
GO:0098918	structural constituent of synapse	3/616	30/18639	0.1	3.02581168831169	0.0754556708727293	0.288015901161013
GO:0034236	protein kinase A catalytic subunit binding	2/616	14/18639	0.142857142857143	4.32258812615955	0.0763385496463199	0.288926915749996
GO:1901474	azole transmembrane transporter activity	2/616	14/18639	0.142857142857143	4.32258812615955	0.0763385496463199	0.288926915749996
GO:0001222	transcription corepressor binding	4/616	49/18639	0.0816326530612245	2.47005035780546	0.0779753809387963	0.293882002950001
GO:0047499	calcium-independent phospholipase A2 activity	3/616	31/18639	0.0967741935483871	2.92820485965647	0.0815777408668508	0.306172525345461
GO:0048020	CCR chemokine receptor binding	4/616	50/18639	0.08	2.42064935064935	0.0826526363737583	0.308914228446922
GO:0008237	metallopeptidase activity	10/616	184/18639	0.0543478260869565	1.64446287408244	0.0850657144225413	0.313093533283572
GO:0004467	long-chain fatty acid-CoA ligase activity	2/616	15/18639	0.133333333333333	4.03441558441558	0.0862141613389545	0.313093533283572
GO:0008252	nucleotidase activity	2/616	15/18639	0.133333333333333	4.03441558441558	0.0862141613389545	0.313093533283572
GO:0033130	acetylcholine receptor binding	2/616	15/18639	0.133333333333333	4.03441558441558	0.0862141613389545	0.313093533283572
GO:0034483	heparan sulfate sulfotransferase activity	2/616	15/18639	0.133333333333333	4.03441558441558	0.0862141613389545	0.313093533283572
GO:0047372	monoacylglycerol lipase activity	2/616	15/18639	0.133333333333333	4.03441558441558	0.0862141613389545	0.313093533283572
GO:0120283	protein serine/threonine kinase binding	2/616	15/18639	0.133333333333333	4.03441558441558	0.0862141613389545	0.313093533283572
GO:0047498	calcium-dependent phospholipase A2 activity	3/616	32/18639	0.09375	2.83669845779221	0.0879064354881312	0.31415168379623
GO:0071813	lipoprotein particle binding	3/616	32/18639	0.09375	2.83669845779221	0.0879064354881312	0.31415168379623
GO:0071814	protein-lipid complex binding	3/616	32/18639	0.09375	2.83669845779221	0.0879064354881312	0.31415168379623
GO:0120015	sterol transfer activity	3/616	32/18639	0.09375	2.83669845779221	0.0879064354881312	0.31415168379623
GO:0016410	N-acyltransferase activity	6/616	94/18639	0.0638297872340425	1.93136916275214	0.0910757862299809	0.324186429556718
GO:0005080	protein kinase C binding	4/616	52/18639	0.0769230769230769	2.32754745254745	0.0924090250034713	0.32763199773958
GO:0043539	protein serine/threonine kinase activator activity	5/616	73/18639	0.0684931506849315	2.07247375911759	0.0936575065885353	0.330751115787072
GO:0071889	14-3-3 protein binding	3/616	33/18639	0.0909090909090909	2.75073789846517	0.0944346470796294	0.332187758550696
GO:0005024	transforming growth factor beta receptor activity	2/616	16/18639	0.125	3.78226461038961	0.0964463367913862	0.334024571821905
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	2/616	16/18639	0.125	3.78226461038961	0.0964463367913862	0.334024571821905
GO:0030275	LRR domain binding	2/616	16/18639	0.125	3.78226461038961	0.0964463367913862	0.334024571821905
GO:0070411	I-SMAD binding	2/616	16/18639	0.125	3.78226461038961	0.0964463367913862	0.334024571821905
GO:0048029	monosaccharide binding	5/616	74/18639	0.0675675675675676	2.04446735696736	0.0978729837942812	0.33766179409027
GO:0019902	phosphatase binding	10/616	190/18639	0.0526315789473684	1.59253246753247	0.0998022502001073	0.342998538044047
GO:0019825	oxygen binding	3/616	34/18639	0.0882352941176471	2.66983384262796	0.101155076612372	0.345004196658926
GO:0090482	vitamin transmembrane transporter activity	3/616	34/18639	0.0882352941176471	2.66983384262796	0.101155076612372	0.345004196658926
GO:0015485	cholesterol binding	4/616	54/18639	0.0740740740740741	2.24134199134199	0.102685077301996	0.3488958876511
GO:0019955	cytokine binding	8/616	144/18639	0.0555555555555556	1.68100649350649	0.105065966358183	0.35548047644995
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	2/616	17/18639	0.117647058823529	3.55977845683728	0.10700081230935	0.35548047644995
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	2/616	17/18639	0.117647058823529	3.55977845683728	0.10700081230935	0.35548047644995
GO:0008429	phosphatidylethanolamine binding	2/616	17/18639	0.117647058823529	3.55977845683728	0.10700081230935	0.35548047644995
GO:0015347	sodium-independent organic anion transmembrane transporter activity	2/616	17/18639	0.117647058823529	3.55977845683728	0.10700081230935	0.35548047644995
GO:0038191	neuropilin binding	2/616	17/18639	0.117647058823529	3.55977845683728	0.10700081230935	0.35548047644995
GO:0004623	phospholipase A2 activity	3/616	35/18639	0.0857142857142857	2.59355287569573	0.108060268290021	0.357675500576196
GO:0170055	lipid transmembrane transporter activity	4/616	56/18639	0.0714285714285714	2.16129406307978	0.113459472391336	0.374165980643488
GO:0001664	G protein-coupled receptor binding	14/616	297/18639	0.0471380471380471	1.4263085399449	0.117000047146002	0.382996877267742
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	2/616	18/18639	0.111111111111111	3.36201298701299	0.117845193005459	0.382996877267742
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	2/616	18/18639	0.111111111111111	3.36201298701299	0.117845193005459	0.382996877267742
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	2/616	18/18639	0.111111111111111	3.36201298701299	0.117845193005459	0.382996877267742
GO:0004601	peroxidase activity	4/616	57/18639	0.0701754385964912	2.12337662337662	0.119026354443914	0.385439133343648
GO:0048306	calcium-dependent protein binding	5/616	80/18639	0.0625	1.89113230519481	0.125097814043338	0.403642946751347
GO:0030971	receptor tyrosine kinase binding	5/616	81/18639	0.0617283950617284	1.86778499278499	0.129943826822013	0.41777638946002
GO:0031490	chromatin DNA binding	7/616	128/18639	0.0546875	1.65474076704545	0.131830538816195	0.42232854756474
GO:0003774	cytoskeletal motor activity	8/616	153/18639	0.0522875816993464	1.58212375859435	0.134957434485022	0.430807184103433
GO:0005319	lipid transporter activity	9/616	178/18639	0.050561797752809	1.52990478622501	0.136319597054571	0.43361233531188
GO:0016776	phosphotransferase activity, phosphate group as acceptor	3/616	39/18639	0.0769230769230769	2.32754745254745	0.137375783615278	0.435427837112737
GO:0008013	beta-catenin binding	6/616	106/18639	0.0566037735849057	1.71272359715756	0.13887082570074	0.438445234466777
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	2/616	20/18639	0.1	3.02581168831169	0.140282923402414	0.438445234466777
GO:0031418	L-ascorbic acid binding	2/616	20/18639	0.1	3.02581168831169	0.140282923402414	0.438445234466777
GO:0052745	inositol phosphate phosphatase activity	2/616	20/18639	0.1	3.02581168831169	0.140282923402414	0.438445234466777
GO:0030331	nuclear estrogen receptor binding	3/616	40/18639	0.075	2.26935876623377	0.145089576848269	0.451893577892006
GO:0001846	opsonin binding	2/616	21/18639	0.0952380952380952	2.8817254174397	0.151820073343982	0.465046582658654
GO:0015174	basic amino acid transmembrane transporter activity	2/616	21/18639	0.0952380952380952	2.8817254174397	0.151820073343982	0.465046582658654
GO:0019200	carbohydrate kinase activity	2/616	21/18639	0.0952380952380952	2.8817254174397	0.151820073343982	0.465046582658654
GO:0061891	calcium ion sensor activity	2/616	21/18639	0.0952380952380952	2.8817254174397	0.151820073343982	0.465046582658654
GO:0001727	lipid kinase activity	3/616	41/18639	0.0731707317073171	2.21400855242319	0.152941741231107	0.465046582658654
GO:0015175	neutral L-amino acid transmembrane transporter activity	3/616	41/18639	0.0731707317073171	2.21400855242319	0.152941741231107	0.465046582658654
GO:0042169	SH2 domain binding	3/616	41/18639	0.0731707317073171	2.21400855242319	0.152941741231107	0.465046582658654
GO:0005125	cytokine activity	11/616	234/18639	0.047008547008547	1.42239010989011	0.153681252570954	0.465716498500493
GO:0035198	miRNA binding	3/616	42/18639	0.0714285714285714	2.16129406307978	0.160924496798205	0.486024490329933
GO:0005243	gap junction channel activity	2/616	22/18639	0.0909090909090909	2.75073789846517	0.163534574897607	0.49060372469282
GO:0140784	metal ion sensor activity	2/616	22/18639	0.0909090909090909	2.75073789846517	0.163534574897607	0.49060372469282
GO:0016922	nuclear receptor binding	7/616	137/18639	0.0510948905109489	1.54603516921035	0.168562766119203	0.504002670696418
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	2/616	23/18639	0.0869565217391304	2.6311405985319	0.175402160776202	0.512979272071109
GO:0004602	glutathione peroxidase activity	2/616	23/18639	0.0869565217391304	2.6311405985319	0.175402160776202	0.512979272071109
GO:0005283	amino acid:sodium symporter activity	2/616	23/18639	0.0869565217391304	2.6311405985319	0.175402160776202	0.512979272071109
GO:0017134	fibroblast growth factor binding	2/616	23/18639	0.0869565217391304	2.6311405985319	0.175402160776202	0.512979272071109
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	2/616	23/18639	0.0869565217391304	2.6311405985319	0.175402160776202	0.512979272071109
GO:0019210	kinase inhibitor activity	5/616	90/18639	0.0555555555555556	1.68100649350649	0.177115201224113	0.512979272071109
GO:0019205	nucleobase-containing compound kinase activity	3/616	44/18639	0.0681818181818182	2.06305342384888	0.177250878176681	0.512979272071109
GO:0030020	extracellular matrix structural constituent conferring tensile strength	3/616	44/18639	0.0681818181818182	2.06305342384888	0.177250878176681	0.512979272071109
GO:0030547	signaling receptor inhibitor activity	3/616	44/18639	0.0681818181818182	2.06305342384888	0.177250878176681	0.512979272071109
GO:0070851	growth factor receptor binding	7/616	139/18639	0.0503597122302158	1.523790058862	0.177283806401387	0.512979272071109
GO:0017124	SH3 domain binding	6/616	115/18639	0.0521739130434783	1.57868435911914	0.180955864927333	0.521920935176263
GO:0042605	peptide antigen binding	3/616	45/18639	0.0666666666666667	2.01720779220779	0.185579208374777	0.529245605436853
GO:0032934	sterol binding	4/616	68/18639	0.0588235294117647	1.77988922841864	0.187171634666273	0.529245605436853
GO:0004622	lysophospholipase activity	2/616	24/18639	0.0833333333333333	2.52150974025974	0.187399969266184	0.529245605436853
GO:0030552	cAMP binding	2/616	24/18639	0.0833333333333333	2.52150974025974	0.187399969266184	0.529245605436853
GO:0050699	WW domain binding	2/616	24/18639	0.0833333333333333	2.52150974025974	0.187399969266184	0.529245605436853
GO:0060229	lipase activator activity	2/616	24/18639	0.0833333333333333	2.52150974025974	0.187399969266184	0.529245605436853
GO:0004175	endopeptidase activity	17/616	405/18639	0.0419753086419753	1.27009379509379	0.187625532362229	0.529245605436853
GO:0043178	alcohol binding	5/616	92/18639	0.0543478260869565	1.64446287408244	0.188382302517668	0.52971449955595
GO:0019208	phosphatase regulator activity	6/616	117/18639	0.0512820512820513	1.5516983016983	0.190937204406561	0.535220851102142
GO:0001848	complement binding	2/616	25/18639	0.08	2.42064935064935	0.199506478077628	0.550637879494254
GO:0008483	transaminase activity	2/616	25/18639	0.08	2.42064935064935	0.199506478077628	0.550637879494254
GO:0015645	fatty acid ligase activity	2/616	25/18639	0.08	2.42064935064935	0.199506478077628	0.550637879494254
GO:0019211	phosphatase activator activity	2/616	25/18639	0.08	2.42064935064935	0.199506478077628	0.550637879494254
GO:0120515	fatty acid-CoA ligase activity	2/616	25/18639	0.08	2.42064935064935	0.199506478077628	0.550637879494254
GO:0031625	ubiquitin protein ligase binding	13/616	302/18639	0.043046357615894	1.30250172013417	0.201795657053403	0.555247559438351
GO:0016879	ligase activity, forming carbon-nitrogen bonds	3/616	48/18639	0.0625	1.89113230519481	0.211134758128708	0.570258836622205
GO:0004896	cytokine receptor activity	5/616	96/18639	0.0520833333333333	1.57594358766234	0.211647967927908	0.570258836622205
GO:0004435	phosphatidylinositol phospholipase C activity	2/616	26/18639	0.0769230769230769	2.32754745254745	0.211701441020283	0.570258836622205
GO:0008198	ferrous iron binding	2/616	26/18639	0.0769230769230769	2.32754745254745	0.211701441020283	0.570258836622205
GO:0019865	immunoglobulin binding	2/616	26/18639	0.0769230769230769	2.32754745254745	0.211701441020283	0.570258836622205
GO:0050750	low-density lipoprotein particle receptor binding	2/616	26/18639	0.0769230769230769	2.32754745254745	0.211701441020283	0.570258836622205
GO:0070006	metalloaminopeptidase activity	2/616	26/18639	0.0769230769230769	2.32754745254745	0.211701441020283	0.570258836622205
GO:0042379	chemokine receptor binding	4/616	72/18639	0.0555555555555556	1.68100649350649	0.214533456457131	0.576157216892354
GO:0016763	pentosyltransferase activity	3/616	49/18639	0.0612244897959184	1.85253776835409	0.219819065336745	0.586838397640061
GO:0035254	glutamate receptor binding	3/616	49/18639	0.0612244897959184	1.85253776835409	0.219819065336745	0.586838397640061
GO:0008266	poly(U) RNA binding	2/616	27/18639	0.0740740740740741	2.24134199134199	0.22396582739137	0.589141780557358
GO:0016405	CoA-ligase activity	2/616	27/18639	0.0740740740740741	2.24134199134199	0.22396582739137	0.589141780557358
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	2/616	27/18639	0.0740740740740741	2.24134199134199	0.22396582739137	0.589141780557358
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	2/616	27/18639	0.0740740740740741	2.24134199134199	0.22396582739137	0.589141780557358
GO:0035255	ionotropic glutamate receptor binding	2/616	27/18639	0.0740740740740741	2.24134199134199	0.22396582739137	0.589141780557358
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	10/616	229/18639	0.0436681222707424	1.32131514773436	0.2275664405055	0.596862857115302
GO:0005242	inward rectifier potassium channel activity	2/616	28/18639	0.0714285714285714	2.16129406307978	0.236281763965549	0.612557058604329
GO:0036408	histone H3K14 acetyltransferase activity	2/616	28/18639	0.0714285714285714	2.16129406307978	0.236281763965549	0.612557058604329
GO:0050698	proteoglycan sulfotransferase activity	2/616	28/18639	0.0714285714285714	2.16129406307978	0.236281763965549	0.612557058604329
GO:0051959	dynein light intermediate chain binding	2/616	28/18639	0.0714285714285714	2.16129406307978	0.236281763965549	0.612557058604329
GO:0016597	amino acid binding	3/616	51/18639	0.0588235294117647	1.77988922841864	0.237393728447936	0.613666208696827
GO:0046982	protein heterodimerization activity	15/616	369/18639	0.040650406504065	1.23000475134621	0.241306693661733	0.621988805214295
GO:0015171	amino acid transmembrane transporter activity	5/616	102/18639	0.0490196078431373	1.4832410236822	0.248112115683759	0.635394114230986
GO:0005416	amino acid:monoatomic cation symporter activity	2/616	29/18639	0.0689655172413793	2.08676668159427	0.24863247948169	0.635394114230986
GO:0010484	histone H3 acetyltransferase activity	2/616	29/18639	0.0689655172413793	2.08676668159427	0.24863247948169	0.635394114230986
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	19/616	484/18639	0.0392561983471074	1.1878186379736	0.252210174874577	0.642706042223
GO:0051018	protein kinase A binding	3/616	53/18639	0.0566037735849057	1.71272359715756	0.255197560877519	0.644639825278793
GO:0016798	hydrolase activity, acting on glycosyl bonds	6/616	130/18639	0.0461538461538462	1.39652847152847	0.260301028326245	0.644639825278793
GO:0001965	G-protein alpha-subunit binding	2/616	30/18639	0.0666666666666667	2.01720779220779	0.261002251525187	0.644639825278793
GO:0008187	poly-pyrimidine tract binding	2/616	30/18639	0.0666666666666667	2.01720779220779	0.261002251525187	0.644639825278793
GO:0016769	transferase activity, transferring nitrogenous groups	2/616	30/18639	0.0666666666666667	2.01720779220779	0.261002251525187	0.644639825278793
GO:0031210	phosphatidylcholine binding	2/616	30/18639	0.0666666666666667	2.01720779220779	0.261002251525187	0.644639825278793
GO:0043995	histone H4K5 acetyltransferase activity	2/616	30/18639	0.0666666666666667	2.01720779220779	0.261002251525187	0.644639825278793
GO:0043996	histone H4K8 acetyltransferase activity	2/616	30/18639	0.0666666666666667	2.01720779220779	0.261002251525187	0.644639825278793
GO:0043997	histone H4K12 acetyltransferase activity	2/616	30/18639	0.0666666666666667	2.01720779220779	0.261002251525187	0.644639825278793
GO:0048019	receptor antagonist activity	2/616	30/18639	0.0666666666666667	2.01720779220779	0.261002251525187	0.644639825278793
GO:0044389	ubiquitin-like protein ligase binding	13/616	322/18639	0.0403726708074534	1.22160099217553	0.269087422747312	0.644639825278793
GO:0016757	glycosyltransferase activity	11/616	267/18639	0.0411985018726592	1.24658908507223	0.270014146960471	0.644639825278793
GO:0001216	DNA-binding transcription activator activity	19/616	491/18639	0.0386965376782077	1.17088436003915	0.272093684930333	0.644639825278793
GO:0140313	molecular sequestering activity	3/616	55/18639	0.0545454545454545	1.6504427390791	0.273177969440433	0.644639825278793
GO:0016878	acid-thiol ligase activity	2/616	31/18639	0.0645161290322581	1.95213657310431	0.273376355708521	0.644639825278793
GO:0017147	Wnt-protein binding	2/616	31/18639	0.0645161290322581	1.95213657310431	0.273376355708521	0.644639825278793
GO:0031406	carboxylic acid binding	8/616	187/18639	0.0427807486631016	1.29446489339537	0.278576422089387	0.644639825278793
GO:0019888	protein phosphatase regulator activity	5/616	107/18639	0.0467289719626168	1.41393069547275	0.279627875430517	0.644639825278793
GO:0005381	iron ion transmembrane transporter activity	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:0005522	profilin binding	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:0005528	FK506 binding	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:0008401	retinoic acid 4-hydroxylase activity	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:0015203	polyamine transmembrane transporter activity	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:0015643	toxic substance binding	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:0015924	mannosyl-oligosaccharide mannosidase activity	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:0016303	1-phosphatidylinositol-3-kinase activity	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:0016868	intramolecular phosphotransferase activity	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:0030957	Tat protein binding	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:0031720	haptoglobin binding	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:0035256	G protein-coupled glutamate receptor binding	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:0035374	chondroitin sulfate binding	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:0043121	neurotrophin binding	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:0043422	protein kinase B binding	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:0050815	phosphoserine residue binding	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:0051880	G-quadruplex DNA binding	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:0070097	delta-catenin binding	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:0140999	histone H3K4 trimethyltransferase activity	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:1905394	retromer complex binding	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:1990757	ubiquitin ligase activator activity	1/616	10/18639	0.1	3.02581168831169	0.285489040433562	0.644639825278793
GO:0043425	bHLH transcription factor binding	2/616	32/18639	0.0625	1.89113230519481	0.285741017056547	0.644639825278793
GO:0005496	steroid binding	5/616	108/18639	0.0462962962962963	1.40083874458874	0.286027481004414	0.644639825278793
GO:0043177	organic acid binding	8/616	189/18639	0.0423280423280423	1.28076685219542	0.288144367634419	0.64778320242625
GO:0140311	protein sequestering activity	2/616	33/18639	0.0606060606060606	1.83382526564345	0.298083363506671	0.650516516704429
GO:0061980	regulatory RNA binding	3/616	58/18639	0.0517241379310345	1.5650750111957	0.300370835361354	0.650516516704429
GO:0033218	amide binding	10/616	247/18639	0.0404858299595142	1.22502497502498	0.301254906153337	0.650516516704429
GO:0004860	protein kinase inhibitor activity	4/616	84/18639	0.0476190476190476	1.44086270871985	0.301756594903744	0.650516516704429
GO:0051117	ATPase binding	4/616	84/18639	0.0476190476190476	1.44086270871985	0.301756594903744	0.650516516704429
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	1/616	11/18639	0.0909090909090909	2.75073789846517	0.309115577074977	0.650516516704429
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	1/616	11/18639	0.0909090909090909	2.75073789846517	0.309115577074977	0.650516516704429
GO:0001851	complement component C3b binding	1/616	11/18639	0.0909090909090909	2.75073789846517	0.309115577074977	0.650516516704429
GO:0002162	dystroglycan binding	1/616	11/18639	0.0909090909090909	2.75073789846517	0.309115577074977	0.650516516704429
GO:0005114	type II transforming growth factor beta receptor binding	1/616	11/18639	0.0909090909090909	2.75073789846517	0.309115577074977	0.650516516704429
GO:0008199	ferric iron binding	1/616	11/18639	0.0909090909090909	2.75073789846517	0.309115577074977	0.650516516704429
GO:0008432	JUN kinase binding	1/616	11/18639	0.0909090909090909	2.75073789846517	0.309115577074977	0.650516516704429
GO:0015173	aromatic amino acid transmembrane transporter activity	1/616	11/18639	0.0909090909090909	2.75073789846517	0.309115577074977	0.650516516704429
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/616	11/18639	0.0909090909090909	2.75073789846517	0.309115577074977	0.650516516704429
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	1/616	11/18639	0.0909090909090909	2.75073789846517	0.309115577074977	0.650516516704429
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	1/616	11/18639	0.0909090909090909	2.75073789846517	0.309115577074977	0.650516516704429
GO:0032050	clathrin heavy chain binding	1/616	11/18639	0.0909090909090909	2.75073789846517	0.309115577074977	0.650516516704429
GO:0032794	GTPase activating protein binding	1/616	11/18639	0.0909090909090909	2.75073789846517	0.309115577074977	0.650516516704429
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/616	11/18639	0.0909090909090909	2.75073789846517	0.309115577074977	0.650516516704429
GO:0034713	type I transforming growth factor beta receptor binding	1/616	11/18639	0.0909090909090909	2.75073789846517	0.309115577074977	0.650516516704429
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/616	11/18639	0.0909090909090909	2.75073789846517	0.309115577074977	0.650516516704429
GO:0050786	RAGE receptor binding	1/616	11/18639	0.0909090909090909	2.75073789846517	0.309115577074977	0.650516516704429
GO:0050998	nitric-oxide synthase binding	1/616	11/18639	0.0909090909090909	2.75073789846517	0.309115577074977	0.650516516704429
GO:0140031	phosphorylation-dependent protein binding	1/616	11/18639	0.0909090909090909	2.75073789846517	0.309115577074977	0.650516516704429
GO:0140537	transcription regulator activator activity	1/616	11/18639	0.0909090909090909	2.75073789846517	0.309115577074977	0.650516516704429
GO:0180030	inositol phosphate kinase activity	1/616	11/18639	0.0909090909090909	2.75073789846517	0.309115577074977	0.650516516704429
GO:0015035	protein-disulfide reductase activity	2/616	34/18639	0.0588235294117647	1.77988922841864	0.310391381437565	0.650516516704429
GO:0030332	cyclin binding	2/616	34/18639	0.0588235294117647	1.77988922841864	0.310391381437565	0.650516516704429
GO:0052866	phosphatidylinositol phosphate phosphatase activity	2/616	34/18639	0.0588235294117647	1.77988922841864	0.310391381437565	0.650516516704429
GO:0016874	ligase activity	7/616	167/18639	0.0419161676646707	1.26830430048993	0.315310632899313	0.6558810416043
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	3/616	60/18639	0.05	1.51290584415584	0.318579366326	0.6558810416043
GO:0005154	epidermal growth factor receptor binding	2/616	35/18639	0.0571428571428571	1.72903525046382	0.322653873143477	0.6558810416043
GO:0005343	organic acid:sodium symporter activity	2/616	35/18639	0.0571428571428571	1.72903525046382	0.322653873143477	0.6558810416043
GO:0010485	histone H4 acetyltransferase activity	2/616	35/18639	0.0571428571428571	1.72903525046382	0.322653873143477	0.6558810416043
GO:0008081	phosphoric diester hydrolase activity	4/616	87/18639	0.0459770114942529	1.39117778772951	0.324267526783971	0.6558810416043
GO:0015026	coreceptor activity	3/616	61/18639	0.0491803278688525	1.48810410900575	0.327691093136524	0.6558810416043
GO:0020037	heme binding	6/616	142/18639	0.0422535211267606	1.27851198097677	0.329185049766253	0.6558810416043
GO:0004000	adenosine deaminase activity	1/616	12/18639	0.0833333333333333	2.52150974025974	0.331962087946881	0.6558810416043
GO:0004126	cytidine deaminase activity	1/616	12/18639	0.0833333333333333	2.52150974025974	0.331962087946881	0.6558810416043
GO:0004300	enoyl-CoA hydratase activity	1/616	12/18639	0.0833333333333333	2.52150974025974	0.331962087946881	0.6558810416043
GO:0005165	neurotrophin receptor binding	1/616	12/18639	0.0833333333333333	2.52150974025974	0.331962087946881	0.6558810416043
GO:0005436	sodium:phosphate symporter activity	1/616	12/18639	0.0833333333333333	2.52150974025974	0.331962087946881	0.6558810416043
GO:0008504	monoamine transmembrane transporter activity	1/616	12/18639	0.0833333333333333	2.52150974025974	0.331962087946881	0.6558810416043
GO:0015269	calcium-activated potassium channel activity	1/616	12/18639	0.0833333333333333	2.52150974025974	0.331962087946881	0.6558810416043
GO:0016208	AMP binding	1/616	12/18639	0.0833333333333333	2.52150974025974	0.331962087946881	0.6558810416043
GO:0031543	peptidyl-proline dioxygenase activity	1/616	12/18639	0.0833333333333333	2.52150974025974	0.331962087946881	0.6558810416043
GO:0035197	siRNA binding	1/616	12/18639	0.0833333333333333	2.52150974025974	0.331962087946881	0.6558810416043
GO:0042301	phosphate ion binding	1/616	12/18639	0.0833333333333333	2.52150974025974	0.331962087946881	0.6558810416043
GO:0043047	single-stranded telomeric DNA binding	1/616	12/18639	0.0833333333333333	2.52150974025974	0.331962087946881	0.6558810416043
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	1/616	12/18639	0.0833333333333333	2.52150974025974	0.331962087946881	0.6558810416043
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/616	12/18639	0.0833333333333333	2.52150974025974	0.331962087946881	0.6558810416043
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/616	12/18639	0.0833333333333333	2.52150974025974	0.331962087946881	0.6558810416043
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/616	12/18639	0.0833333333333333	2.52150974025974	0.331962087946881	0.6558810416043
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/616	12/18639	0.0833333333333333	2.52150974025974	0.331962087946881	0.6558810416043
GO:1990459	transferrin receptor binding	1/616	12/18639	0.0833333333333333	2.52150974025974	0.331962087946881	0.6558810416043
GO:0005507	copper ion binding	3/616	63/18639	0.0476190476190476	1.44086270871985	0.34590364309762	0.670014121544461
GO:0008194	UDP-glycosyltransferase activity	6/616	145/18639	0.0413793103448276	1.25206000895656	0.346812923283622	0.670014121544461
GO:0022829	wide pore channel activity	2/616	37/18639	0.0540540540540541	1.63557388557389	0.347001324465747	0.670014121544461
GO:0030280	structural constituent of skin epidermis	2/616	37/18639	0.0540540540540541	1.63557388557389	0.347001324465747	0.670014121544461
GO:0030551	cyclic nucleotide binding	2/616	37/18639	0.0540540540540541	1.63557388557389	0.347001324465747	0.670014121544461
GO:0000287	magnesium ion binding	9/616	230/18639	0.0391304347826087	1.18401326933936	0.350657036670032	0.670014121544461
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/616	13/18639	0.0769230769230769	2.32754745254745	0.354054284963294	0.670014121544461
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/616	13/18639	0.0769230769230769	2.32754745254745	0.354054284963294	0.670014121544461
GO:0017154	semaphorin receptor activity	1/616	13/18639	0.0769230769230769	2.32754745254745	0.354054284963294	0.670014121544461
GO:0019855	calcium channel inhibitor activity	1/616	13/18639	0.0769230769230769	2.32754745254745	0.354054284963294	0.670014121544461
GO:0035325	Toll-like receptor binding	1/616	13/18639	0.0769230769230769	2.32754745254745	0.354054284963294	0.670014121544461
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/616	13/18639	0.0769230769230769	2.32754745254745	0.354054284963294	0.670014121544461
GO:0070123	transforming growth factor beta receptor activity, type III	1/616	13/18639	0.0769230769230769	2.32754745254745	0.354054284963294	0.670014121544461
GO:0070700	BMP receptor binding	1/616	13/18639	0.0769230769230769	2.32754745254745	0.354054284963294	0.670014121544461
GO:0071837	HMG box domain binding	1/616	13/18639	0.0769230769230769	2.32754745254745	0.354054284963294	0.670014121544461
GO:0089720	caspase binding	1/616	13/18639	0.0769230769230769	2.32754745254745	0.354054284963294	0.670014121544461
GO:0097157	pre-mRNA intronic binding	1/616	13/18639	0.0769230769230769	2.32754745254745	0.354054284963294	0.670014121544461
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/616	13/18639	0.0769230769230769	2.32754745254745	0.354054284963294	0.670014121544461
GO:0140666	annealing activity	1/616	13/18639	0.0769230769230769	2.32754745254745	0.354054284963294	0.670014121544461
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/616	13/18639	0.0769230769230769	2.32754745254745	0.354054284963294	0.670014121544461
GO:0005109	frizzled binding	2/616	38/18639	0.0526315789473684	1.59253246753247	0.359067611183327	0.676646317713119
GO:0043531	ADP binding	2/616	38/18639	0.0526315789473684	1.59253246753247	0.359067611183327	0.676646317713119
GO:0004252	serine-type endopeptidase activity	7/616	176/18639	0.0397727272727273	1.20344783057851	0.363588264980115	0.677563539937516
GO:0038024	cargo receptor activity	3/616	65/18639	0.0461538461538462	1.39652847152847	0.364069224961105	0.677563539937516
GO:0120013	lipid transfer activity	3/616	65/18639	0.0461538461538462	1.39652847152847	0.364069224961105	0.677563539937516
GO:0051213	dioxygenase activity	4/616	93/18639	0.043010752688172	1.30142438206954	0.369523809223047	0.677563539937516
GO:0000217	DNA secondary structure binding	2/616	39/18639	0.0512820512820513	1.5516983016983	0.371050953214033	0.677563539937516
GO:0005344	oxygen carrier activity	1/616	14/18639	0.0714285714285714	2.16129406307978	0.37541703383383	0.677563539937516
GO:0008191	metalloendopeptidase inhibitor activity	1/616	14/18639	0.0714285714285714	2.16129406307978	0.37541703383383	0.677563539937516
GO:0008195	phosphatidate phosphatase activity	1/616	14/18639	0.0714285714285714	2.16129406307978	0.37541703383383	0.677563539937516
GO:0008494	translation activator activity	1/616	14/18639	0.0714285714285714	2.16129406307978	0.37541703383383	0.677563539937516
GO:0008559	ABC-type xenobiotic transporter activity	1/616	14/18639	0.0714285714285714	2.16129406307978	0.37541703383383	0.677563539937516
GO:0016530	metallochaperone activity	1/616	14/18639	0.0714285714285714	2.16129406307978	0.37541703383383	0.677563539937516
GO:0019992	diacylglycerol binding	1/616	14/18639	0.0714285714285714	2.16129406307978	0.37541703383383	0.677563539937516
GO:0032036	myosin heavy chain binding	1/616	14/18639	0.0714285714285714	2.16129406307978	0.37541703383383	0.677563539937516
GO:0042043	neurexin family protein binding	1/616	14/18639	0.0714285714285714	2.16129406307978	0.37541703383383	0.677563539937516
GO:0043176	amine binding	1/616	14/18639	0.0714285714285714	2.16129406307978	0.37541703383383	0.677563539937516
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	1/616	14/18639	0.0714285714285714	2.16129406307978	0.37541703383383	0.677563539937516
GO:0070742	C2H2 zinc finger domain binding	1/616	14/18639	0.0714285714285714	2.16129406307978	0.37541703383383	0.677563539937516
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	1/616	14/18639	0.0714285714285714	2.16129406307978	0.37541703383383	0.677563539937516
GO:0098847	sequence-specific single stranded DNA binding	1/616	14/18639	0.0714285714285714	2.16129406307978	0.37541703383383	0.677563539937516
GO:1901612	cardiolipin binding	1/616	14/18639	0.0714285714285714	2.16129406307978	0.37541703383383	0.677563539937516
GO:1990825	sequence-specific mRNA binding	1/616	14/18639	0.0714285714285714	2.16129406307978	0.37541703383383	0.677563539937516
GO:0019842	vitamin binding	6/616	150/18639	0.04	1.21032467532468	0.376356639300381	0.677785443856252
GO:0005516	calmodulin binding	8/616	207/18639	0.0386473429951691	1.16939582156973	0.377051211242218	0.677785443856252
GO:0004177	aminopeptidase activity	2/616	40/18639	0.05	1.51290584415584	0.382943657233283	0.680198931758921
GO:0015036	disulfide oxidoreductase activity	2/616	40/18639	0.05	1.51290584415584	0.382943657233283	0.680198931758921
GO:0050997	quaternary ammonium group binding	2/616	40/18639	0.05	1.51290584415584	0.382943657233283	0.680198931758921
GO:0061791	GTPase motor activity	2/616	40/18639	0.05	1.51290584415584	0.382943657233283	0.680198931758921
GO:0071949	FAD binding	2/616	40/18639	0.05	1.51290584415584	0.382943657233283	0.680198931758921
GO:1990606	membrane scission GTPase motor activity	2/616	40/18639	0.05	1.51290584415584	0.382943657233283	0.680198931758921
GO:0046906	tetrapyrrole binding	6/616	152/18639	0.0394736842105263	1.19439935064935	0.388198498785057	0.688170066028056
GO:0016407	acetyltransferase activity	4/616	96/18639	0.0416666666666667	1.26075487012987	0.392112468707327	0.688524652202815
GO:0016877	ligase activity, forming carbon-sulfur bonds	2/616	41/18639	0.0487804878048781	1.47600570161546	0.394738627284677	0.688524652202815
GO:0017080	sodium channel regulator activity	2/616	41/18639	0.0487804878048781	1.47600570161546	0.394738627284677	0.688524652202815
GO:0140318	protein transporter activity	2/616	41/18639	0.0487804878048781	1.47600570161546	0.394738627284677	0.688524652202815
GO:0004559	alpha-mannosidase activity	1/616	15/18639	0.0666666666666667	2.01720779220779	0.396074381869178	0.688524652202815
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/616	15/18639	0.0666666666666667	2.01720779220779	0.396074381869178	0.688524652202815
GO:0005523	tropomyosin binding	1/616	15/18639	0.0666666666666667	2.01720779220779	0.396074381869178	0.688524652202815
GO:0008242	omega peptidase activity	1/616	15/18639	0.0666666666666667	2.01720779220779	0.396074381869178	0.688524652202815
GO:0015929	hexosaminidase activity	1/616	15/18639	0.0666666666666667	2.01720779220779	0.396074381869178	0.688524652202815
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/616	15/18639	0.0666666666666667	2.01720779220779	0.396074381869178	0.688524652202815
GO:0008514	organic anion transmembrane transporter activity	10/616	269/18639	0.0371747211895911	1.12483705885193	0.39772580129545	0.690058111725375
GO:0005506	iron ion binding	6/616	154/18639	0.038961038961039	1.17888767077079	0.400037892496213	0.690200258506233
GO:0002039	p53 binding	3/616	69/18639	0.0434782608695652	1.31557029926595	0.400116091887671	0.690200258506233
GO:0008080	N-acetyltransferase activity	3/616	69/18639	0.0434782608695652	1.31557029926595	0.400116091887671	0.690200258506233
GO:0004402	histone acetyltransferase activity	2/616	42/18639	0.0476190476190476	1.44086270871985	0.406429333809001	0.697563509593093
GO:0042056	chemoattractant activity	2/616	42/18639	0.0476190476190476	1.44086270871985	0.406429333809001	0.697563509593093
GO:0008170	N-methyltransferase activity	4/616	98/18639	0.0408163265306122	1.23502517890273	0.407107845474083	0.697563509593093
GO:0016782	transferase activity, transferring sulphur-containing groups	3/616	70/18639	0.0428571428571429	1.29677643784787	0.409044644741698	0.697563509593093
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	1/616	16/18639	0.0625	1.89113230519481	0.416049584874364	0.697563509593093
GO:0005324	long-chain fatty acid transmembrane transporter activity	1/616	16/18639	0.0625	1.89113230519481	0.416049584874364	0.697563509593093
GO:0005521	lamin binding	1/616	16/18639	0.0625	1.89113230519481	0.416049584874364	0.697563509593093
GO:0015923	mannosidase activity	1/616	16/18639	0.0625	1.89113230519481	0.416049584874364	0.697563509593093
GO:0016722	oxidoreductase activity, acting on metal ions	1/616	16/18639	0.0625	1.89113230519481	0.416049584874364	0.697563509593093
GO:0019841	retinol binding	1/616	16/18639	0.0625	1.89113230519481	0.416049584874364	0.697563509593093
GO:0022841	potassium ion leak channel activity	1/616	16/18639	0.0625	1.89113230519481	0.416049584874364	0.697563509593093
GO:0034450	ubiquitin-ubiquitin ligase activity	1/616	16/18639	0.0625	1.89113230519481	0.416049584874364	0.697563509593093
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	1/616	16/18639	0.0625	1.89113230519481	0.416049584874364	0.697563509593093
GO:0097027	ubiquitin-protein transferase activator activity	1/616	16/18639	0.0625	1.89113230519481	0.416049584874364	0.697563509593093
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	1/616	16/18639	0.0625	1.89113230519481	0.416049584874364	0.697563509593093
GO:0005245	voltage-gated calcium channel activity	2/616	43/18639	0.0465116279069767	1.40735427363334	0.418009784062491	0.69823980689768
GO:0008200	ion channel inhibitor activity	2/616	43/18639	0.0465116279069767	1.40735427363334	0.418009784062491	0.69823980689768
GO:0008017	microtubule binding	10/616	276/18639	0.036231884057971	1.09630858272163	0.428943536062715	0.713404853700591
GO:0001046	core promoter sequence-specific DNA binding	2/616	44/18639	0.0454545454545455	1.37536894923259	0.429474493866577	0.713404853700591
GO:0016248	channel inhibitor activity	2/616	44/18639	0.0454545454545455	1.37536894923259	0.429474493866577	0.713404853700591
GO:0005092	GDP-dissociation inhibitor activity	1/616	17/18639	0.0588235294117647	1.77988922841864	0.435365133159678	0.713935145236254
GO:0008569	minus-end-directed microtubule motor activity	1/616	17/18639	0.0588235294117647	1.77988922841864	0.435365133159678	0.713935145236254
GO:0030169	low-density lipoprotein particle binding	1/616	17/18639	0.0588235294117647	1.77988922841864	0.435365133159678	0.713935145236254
GO:0030548	acetylcholine receptor regulator activity	1/616	17/18639	0.0588235294117647	1.77988922841864	0.435365133159678	0.713935145236254
GO:0036041	long-chain fatty acid binding	1/616	17/18639	0.0588235294117647	1.77988922841864	0.435365133159678	0.713935145236254
GO:0045125	bioactive lipid receptor activity	1/616	17/18639	0.0588235294117647	1.77988922841864	0.435365133159678	0.713935145236254
GO:1990226	histone methyltransferase binding	1/616	17/18639	0.0588235294117647	1.77988922841864	0.435365133159678	0.713935145236254
GO:0001217	DNA-binding transcription repressor activity	10/616	278/18639	0.0359712230215827	1.08842147061572	0.437855016740894	0.716707937986463
GO:0141110	transporter inhibitor activity	2/616	45/18639	0.0444444444444444	1.34480519480519	0.440818460633637	0.720244370106325
GO:0140297	DNA-binding transcription factor binding	17/616	488/18639	0.0348360655737705	1.05407374387907	0.447053667964614	0.728580269585421
GO:0003725	double-stranded RNA binding	3/616	75/18639	0.04	1.21032467532468	0.453007672327625	0.728580269585421
GO:0000400	four-way junction DNA binding	1/616	18/18639	0.0555555555555556	1.68100649350649	0.454042776698161	0.728580269585421
GO:0015172	acidic amino acid transmembrane transporter activity	1/616	18/18639	0.0555555555555556	1.68100649350649	0.454042776698161	0.728580269585421
GO:0031690	adrenergic receptor binding	1/616	18/18639	0.0555555555555556	1.68100649350649	0.454042776698161	0.728580269585421
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/616	18/18639	0.0555555555555556	1.68100649350649	0.454042776698161	0.728580269585421
GO:0050811	GABA receptor binding	1/616	18/18639	0.0555555555555556	1.68100649350649	0.454042776698161	0.728580269585421
GO:0099602	neurotransmitter receptor regulator activity	1/616	18/18639	0.0555555555555556	1.68100649350649	0.454042776698161	0.728580269585421
GO:1901611	phosphatidylglycerol binding	1/616	18/18639	0.0555555555555556	1.68100649350649	0.454042776698161	0.728580269585421
GO:1990381	ubiquitin-specific protease binding	1/616	18/18639	0.0555555555555556	1.68100649350649	0.454042776698161	0.728580269585421
GO:0008236	serine-type peptidase activity	7/616	194/18639	0.0360824742268041	1.09178772258669	0.460904066628234	0.72887587584077
GO:0005504	fatty acid binding	2/616	47/18639	0.0425531914893617	1.28757944183476	0.4631264093235	0.72887587584077
GO:0061733	protein-lysine-acetyltransferase activity	2/616	47/18639	0.0425531914893617	1.28757944183476	0.4631264093235	0.72887587584077
GO:0140359	ABC-type transporter activity	2/616	47/18639	0.0425531914893617	1.28757944183476	0.4631264093235	0.72887587584077
GO:0140938	histone H3 methyltransferase activity	2/616	47/18639	0.0425531914893617	1.28757944183476	0.4631264093235	0.72887587584077
GO:0016779	nucleotidyltransferase activity	5/616	136/18639	0.0367647058823529	1.11243076776165	0.468784338350828	0.72887587584077
GO:0003756	protein disulfide isomerase activity	1/616	19/18639	0.0526315789473684	1.59253246753247	0.472103549457623	0.72887587584077
GO:0008301	DNA binding, bending	1/616	19/18639	0.0526315789473684	1.59253246753247	0.472103549457623	0.72887587584077
GO:0008381	mechanosensitive monoatomic ion channel activity	1/616	19/18639	0.0526315789473684	1.59253246753247	0.472103549457623	0.72887587584077
GO:0008574	plus-end-directed microtubule motor activity	1/616	19/18639	0.0526315789473684	1.59253246753247	0.472103549457623	0.72887587584077
GO:0015245	fatty acid transmembrane transporter activity	1/616	19/18639	0.0526315789473684	1.59253246753247	0.472103549457623	0.72887587584077
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	1/616	19/18639	0.0526315789473684	1.59253246753247	0.472103549457623	0.72887587584077
GO:0016918	retinal binding	1/616	19/18639	0.0526315789473684	1.59253246753247	0.472103549457623	0.72887587584077
GO:0022840	leak channel activity	1/616	19/18639	0.0526315789473684	1.59253246753247	0.472103549457623	0.72887587584077
GO:0022842	narrow pore channel activity	1/616	19/18639	0.0526315789473684	1.59253246753247	0.472103549457623	0.72887587584077
GO:0030506	ankyrin binding	1/616	19/18639	0.0526315789473684	1.59253246753247	0.472103549457623	0.72887587584077
GO:0031420	alkali metal ion binding	1/616	19/18639	0.0526315789473684	1.59253246753247	0.472103549457623	0.72887587584077
GO:0042577	lipid phosphatase activity	1/616	19/18639	0.0526315789473684	1.59253246753247	0.472103549457623	0.72887587584077
GO:0042800	histone H3K4 methyltransferase activity	1/616	19/18639	0.0526315789473684	1.59253246753247	0.472103549457623	0.72887587584077
GO:0050145	nucleoside monophosphate kinase activity	1/616	19/18639	0.0526315789473684	1.59253246753247	0.472103549457623	0.72887587584077
GO:0070003	threonine-type peptidase activity	1/616	19/18639	0.0526315789473684	1.59253246753247	0.472103549457623	0.72887587584077
GO:0097001	ceramide binding	1/616	19/18639	0.0526315789473684	1.59253246753247	0.472103549457623	0.72887587584077
GO:0140693	molecular condensate scaffold activity	2/616	48/18639	0.0416666666666667	1.26075487012987	0.4740825680711	0.730673648728139
GO:0016758	hexosyltransferase activity	7/616	197/18639	0.0355329949238579	1.07516151361329	0.476906064631832	0.7337645625639
GO:0017171	serine hydrolase activity	7/616	198/18639	0.0353535353535354	1.06973140495868	0.482213011626624	0.740659368885413
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	12/616	349/18639	0.0343839541547278	1.04039370371749	0.485847749466681	0.744966549182244
GO:0015370	solute:sodium symporter activity	3/616	79/18639	0.0379746835443038	1.14904241328292	0.487178058671265	0.745572682957536
GO:0005326	neurotransmitter transmembrane transporter activity	1/616	20/18639	0.05	1.51290584415584	0.489567792934213	0.745572682957536
GO:0015095	magnesium ion transmembrane transporter activity	1/616	20/18639	0.05	1.51290584415584	0.489567792934213	0.745572682957536
GO:0016004	phospholipase activator activity	1/616	20/18639	0.05	1.51290584415584	0.489567792934213	0.745572682957536
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	1/616	21/18639	0.0476190476190476	1.44086270871985	0.506455178913724	0.760879469058196
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	1/616	21/18639	0.0476190476190476	1.44086270871985	0.506455178913724	0.760879469058196
GO:0008373	sialyltransferase activity	1/616	21/18639	0.0476190476190476	1.44086270871985	0.506455178913724	0.760879469058196
GO:0035613	RNA stem-loop binding	1/616	21/18639	0.0476190476190476	1.44086270871985	0.506455178913724	0.760879469058196
GO:0036122	BMP binding	1/616	21/18639	0.0476190476190476	1.44086270871985	0.506455178913724	0.760879469058196
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	1/616	21/18639	0.0476190476190476	1.44086270871985	0.506455178913724	0.760879469058196
GO:0051010	microtubule plus-end binding	1/616	21/18639	0.0476190476190476	1.44086270871985	0.506455178913724	0.760879469058196
GO:0072542	protein phosphatase activator activity	1/616	21/18639	0.0476190476190476	1.44086270871985	0.506455178913724	0.760879469058196
GO:0022843	voltage-gated monoatomic cation channel activity	5/616	143/18639	0.034965034965035	1.0579761147943	0.512939389568047	0.760879469058196
GO:0001540	amyloid-beta binding	3/616	83/18639	0.036144578313253	1.09366687529338	0.520281636609345	0.760879469058196
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	1/616	22/18639	0.0454545454545455	1.37536894923259	0.522784731485921	0.760879469058196
GO:0030021	extracellular matrix structural constituent conferring compression resistance	1/616	22/18639	0.0454545454545455	1.37536894923259	0.522784731485921	0.760879469058196
GO:0032931	histone H3K56 acetyltransferase activity	1/616	22/18639	0.0454545454545455	1.37536894923259	0.522784731485921	0.760879469058196
GO:0033691	sialic acid binding	1/616	22/18639	0.0454545454545455	1.37536894923259	0.522784731485921	0.760879469058196
GO:0043992	histone H3K9 acetyltransferase activity	1/616	22/18639	0.0454545454545455	1.37536894923259	0.522784731485921	0.760879469058196
GO:0043993	histone H3K18 acetyltransferase activity	1/616	22/18639	0.0454545454545455	1.37536894923259	0.522784731485921	0.760879469058196
GO:0043994	histone H3K23 acetyltransferase activity	1/616	22/18639	0.0454545454545455	1.37536894923259	0.522784731485921	0.760879469058196
GO:0043999	histone H2AK5 acetyltransferase activity	1/616	22/18639	0.0454545454545455	1.37536894923259	0.522784731485921	0.760879469058196
GO:0044012	histone H2AK9 acetyltransferase activity	1/616	22/18639	0.0454545454545455	1.37536894923259	0.522784731485921	0.760879469058196
GO:0044014	histone H2BK5 acetyltransferase activity	1/616	22/18639	0.0454545454545455	1.37536894923259	0.522784731485921	0.760879469058196
GO:0044015	histone H2BK12 acetyltransferase activity	1/616	22/18639	0.0454545454545455	1.37536894923259	0.522784731485921	0.760879469058196
GO:0044016	histone H3K4 acetyltransferase activity	1/616	22/18639	0.0454545454545455	1.37536894923259	0.522784731485921	0.760879469058196
GO:0044017	histone H3K27 acetyltransferase activity	1/616	22/18639	0.0454545454545455	1.37536894923259	0.522784731485921	0.760879469058196
GO:0044018	histone H3K36 acetyltransferase activity	1/616	22/18639	0.0454545454545455	1.37536894923259	0.522784731485921	0.760879469058196
GO:0046972	histone H4K16 acetyltransferase activity	1/616	22/18639	0.0454545454545455	1.37536894923259	0.522784731485921	0.760879469058196
GO:0050321	tau-protein kinase activity	1/616	22/18639	0.0454545454545455	1.37536894923259	0.522784731485921	0.760879469058196
GO:0140908	histone H3K122 acetyltransferase activity	1/616	22/18639	0.0454545454545455	1.37536894923259	0.522784731485921	0.760879469058196
GO:0004864	protein phosphatase inhibitor activity	2/616	53/18639	0.0377358490566038	1.14181573143837	0.526762709347982	0.760879469058196
GO:0005246	calcium channel regulator activity	2/616	53/18639	0.0377358490566038	1.14181573143837	0.526762709347982	0.760879469058196
GO:0008146	sulfotransferase activity	2/616	53/18639	0.0377358490566038	1.14181573143837	0.526762709347982	0.760879469058196
GO:0016860	intramolecular oxidoreductase activity	2/616	53/18639	0.0377358490566038	1.14181573143837	0.526762709347982	0.760879469058196
GO:0034212	protein N-acetyltransferase activity	2/616	53/18639	0.0377358490566038	1.14181573143837	0.526762709347982	0.760879469058196
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	9/616	268/18639	0.0335820895522388	1.01613079085094	0.528120807727606	0.761614733973734
GO:0015294	solute:monoatomic cation symporter activity	4/616	116/18639	0.0344827586206897	1.04338334079713	0.53674657401901	0.766827998345582
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	2/616	54/18639	0.037037037037037	1.120670995671	0.536862471882874	0.766827998345582
GO:0140463	chromatin-protein adaptor activity	2/616	54/18639	0.037037037037037	1.120670995671	0.536862471882874	0.766827998345582
GO:0042171	lysophosphatidic acid acyltransferase activity	1/616	23/18639	0.0434782608695652	1.31557029926595	0.538574848336362	0.766827998345582
GO:0043274	phospholipase binding	1/616	23/18639	0.0434782608695652	1.31557029926595	0.538574848336362	0.766827998345582
GO:0044013	histone H2B acetyltransferase activity	1/616	23/18639	0.0434782608695652	1.31557029926595	0.538574848336362	0.766827998345582
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	1/616	23/18639	0.0434782608695652	1.31557029926595	0.538574848336362	0.766827998345582
GO:0071617	lysophospholipid acyltransferase activity	1/616	23/18639	0.0434782608695652	1.31557029926595	0.538574848336362	0.766827998345582
GO:0050660	flavin adenine dinucleotide binding	3/616	86/18639	0.0348837209302326	1.05551570522501	0.544331116464032	0.77379558077375
GO:0008374	O-acyltransferase activity	2/616	55/18639	0.0363636363636364	1.10029515938607	0.546812830465608	0.77503503781818
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	1/616	24/18639	0.0416666666666667	1.26075487012987	0.553843321339413	0.77503503781818
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	1/616	24/18639	0.0416666666666667	1.26075487012987	0.553843321339413	0.77503503781818
GO:0004806	triacylglycerol lipase activity	1/616	24/18639	0.0416666666666667	1.26075487012987	0.553843321339413	0.77503503781818
GO:0005315	phosphate transmembrane transporter activity	1/616	24/18639	0.0416666666666667	1.26075487012987	0.553843321339413	0.77503503781818
GO:0005540	hyaluronic acid binding	1/616	24/18639	0.0416666666666667	1.26075487012987	0.553843321339413	0.77503503781818
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/616	24/18639	0.0416666666666667	1.26075487012987	0.553843321339413	0.77503503781818
GO:0035035	histone acetyltransferase binding	1/616	24/18639	0.0416666666666667	1.26075487012987	0.553843321339413	0.77503503781818
GO:0043998	histone H2A acetyltransferase activity	1/616	24/18639	0.0416666666666667	1.26075487012987	0.553843321339413	0.77503503781818
GO:0070840	dynein complex binding	1/616	24/18639	0.0416666666666667	1.26075487012987	0.553843321339413	0.77503503781818
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	6/616	181/18639	0.0331491712707182	1.00303149888785	0.554825163945188	0.775199644951455
GO:0019212	phosphatase inhibitor activity	2/616	56/18639	0.0357142857142857	1.08064703153989	0.556612615331566	0.775281857068967
GO:0030170	pyridoxal phosphate binding	2/616	56/18639	0.0357142857142857	1.08064703153989	0.556612615331566	0.775281857068967
GO:0004197	cysteine-type endopeptidase activity	3/616	88/18639	0.0340909090909091	1.03152671192444	0.559969068470991	0.77754218950229
GO:0016651	oxidoreductase activity, acting on NAD(P)H	3/616	88/18639	0.0340909090909091	1.03152671192444	0.559969068470991	0.77754218950229
GO:0070279	vitamin B6 binding	2/616	57/18639	0.0350877192982456	1.06168831168831	0.566260896721066	0.77987889718404
GO:0004709	MAP kinase kinase kinase activity	1/616	25/18639	0.04	1.21032467532468	0.56860735647532	0.77987889718404
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/616	25/18639	0.04	1.21032467532468	0.56860735647532	0.77987889718404
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/616	25/18639	0.04	1.21032467532468	0.56860735647532	0.77987889718404
GO:0019706	protein-cysteine S-palmitoyltransferase activity	1/616	25/18639	0.04	1.21032467532468	0.56860735647532	0.77987889718404
GO:0019707	protein-cysteine S-acyltransferase activity	1/616	25/18639	0.04	1.21032467532468	0.56860735647532	0.77987889718404
GO:0047617	fatty acyl-CoA hydrolase activity	1/616	25/18639	0.04	1.21032467532468	0.56860735647532	0.77987889718404
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	1/616	25/18639	0.04	1.21032467532468	0.56860735647532	0.77987889718404
GO:0042393	histone binding	8/616	247/18639	0.0323886639676113	0.98001998001998	0.573287835916366	0.785097998193863
GO:0042277	peptide binding	8/616	249/18639	0.0321285140562249	0.972148333594117	0.582456567882539	0.786235463165248
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	3/616	91/18639	0.032967032967033	0.997520336806051	0.582807543020337	0.786235463165248
GO:0004112	cyclic-nucleotide phosphodiesterase activity	1/616	26/18639	0.0384615384615385	1.16377372627373	0.582883593093522	0.786235463165248
GO:0005112	Notch binding	1/616	26/18639	0.0384615384615385	1.16377372627373	0.582883593093522	0.786235463165248
GO:0005227	calcium-activated cation channel activity	1/616	26/18639	0.0384615384615385	1.16377372627373	0.582883593093522	0.786235463165248
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	1/616	26/18639	0.0384615384615385	1.16377372627373	0.582883593093522	0.786235463165248
GO:0008157	protein phosphatase 1 binding	1/616	26/18639	0.0384615384615385	1.16377372627373	0.582883593093522	0.786235463165248
GO:0016289	acyl-CoA hydrolase activity	1/616	26/18639	0.0384615384615385	1.16377372627373	0.582883593093522	0.786235463165248
GO:0030247	polysaccharide binding	1/616	26/18639	0.0384615384615385	1.16377372627373	0.582883593093522	0.786235463165248
GO:0034237	protein kinase A regulatory subunit binding	1/616	26/18639	0.0384615384615385	1.16377372627373	0.582883593093522	0.786235463165248
GO:0052689	carboxylic ester hydrolase activity	3/616	92/18639	0.0326086956521739	0.986677724449463	0.590251196661253	0.792450438433747
GO:0140375	immune receptor activity	5/616	156/18639	0.032051282051282	0.969811438561438	0.590496255761881	0.792450438433747
GO:0046943	carboxylic acid transmembrane transporter activity	6/616	188/18639	0.0319148936170213	0.965684581376071	0.592028263798908	0.792450438433747
GO:0001671	ATPase activator activity	1/616	27/18639	0.037037037037037	1.120670995671	0.596688122543605	0.792450438433747
GO:0005044	scavenger receptor activity	1/616	27/18639	0.037037037037037	1.120670995671	0.596688122543605	0.792450438433747
GO:0005385	zinc ion transmembrane transporter activity	1/616	27/18639	0.037037037037037	1.120670995671	0.596688122543605	0.792450438433747
GO:0008320	protein transmembrane transporter activity	1/616	27/18639	0.037037037037037	1.120670995671	0.596688122543605	0.792450438433747
GO:0008395	steroid hydroxylase activity	1/616	27/18639	0.037037037037037	1.120670995671	0.596688122543605	0.792450438433747
GO:0015252	proton channel activity	1/616	27/18639	0.037037037037037	1.120670995671	0.596688122543605	0.792450438433747
GO:0023026	MHC class II protein complex binding	1/616	27/18639	0.037037037037037	1.120670995671	0.596688122543605	0.792450438433747
GO:0005342	organic acid transmembrane transporter activity	6/616	189/18639	0.0317460317460317	0.960575139146568	0.597209026066012	0.792450438433747
GO:0016836	hydro-lyase activity	2/616	61/18639	0.0327868852459016	0.992069406003832	0.603327997603342	0.799387317356275
GO:0016866	intramolecular transferase activity	1/616	28/18639	0.0357142857142857	1.08064703153989	0.610036506194644	0.801175323655338
GO:0019789	SUMO transferase activity	1/616	28/18639	0.0357142857142857	1.08064703153989	0.610036506194644	0.801175323655338
GO:0046625	sphingolipid binding	1/616	28/18639	0.0357142857142857	1.08064703153989	0.610036506194644	0.801175323655338
GO:0046966	nuclear thyroid hormone receptor binding	1/616	28/18639	0.0357142857142857	1.08064703153989	0.610036506194644	0.801175323655338
GO:0051019	mitogen-activated protein kinase binding	1/616	28/18639	0.0357142857142857	1.08064703153989	0.610036506194644	0.801175323655338
GO:0141052	histone H3 demethylase activity	1/616	28/18639	0.0357142857142857	1.08064703153989	0.610036506194644	0.801175323655338
GO:0099106	ion channel regulator activity	5/616	160/18639	0.03125	0.945566152597403	0.612955922189467	0.803832547081801
GO:0016417	S-acyltransferase activity	1/616	29/18639	0.0344827586206897	1.04338334079713	0.622943792862964	0.814548953641514
GO:0106222	lncRNA binding	1/616	29/18639	0.0344827586206897	1.04338334079713	0.622943792862964	0.814548953641514
GO:0031072	heat shock protein binding	4/616	131/18639	0.0305343511450382	0.923911965896699	0.632924330150841	0.82247591413267
GO:0005249	voltage-gated potassium channel activity	3/616	98/18639	0.0306122448979592	0.926268884177047	0.633082117539816	0.82247591413267
GO:0008106	alcohol dehydrogenase (NADP+) activity	1/616	30/18639	0.0333333333333333	1.0086038961039	0.635424535667715	0.82247591413267
GO:0022839	monoatomic ion-gated channel activity	1/616	30/18639	0.0333333333333333	1.0086038961039	0.635424535667715	0.82247591413267
GO:0031624	ubiquitin conjugating enzyme binding	1/616	30/18639	0.0333333333333333	1.0086038961039	0.635424535667715	0.82247591413267
GO:0032452	histone demethylase activity	1/616	30/18639	0.0333333333333333	1.0086038961039	0.635424535667715	0.82247591413267
GO:0051721	protein phosphatase 2A binding	1/616	30/18639	0.0333333333333333	1.0086038961039	0.635424535667715	0.82247591413267
GO:0019843	rRNA binding	2/616	65/18639	0.0307692307692308	0.931018981018981	0.637949758924395	0.823368250007457
GO:0160215	deacylase activity	2/616	65/18639	0.0307692307692308	0.931018981018981	0.637949758924395	0.823368250007457
GO:0008235	metalloexopeptidase activity	2/616	66/18639	0.0303030303030303	0.916912632821724	0.646225598791247	0.830902788375851
GO:0005184	neuropeptide hormone activity	1/616	31/18639	0.032258064516129	0.976068286552157	0.647492808333021	0.830902788375851
GO:0016411	acylglycerol O-acyltransferase activity	1/616	31/18639	0.032258064516129	0.976068286552157	0.647492808333021	0.830902788375851
GO:0140457	protein demethylase activity	1/616	31/18639	0.032258064516129	0.976068286552157	0.647492808333021	0.830902788375851
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	2/616	67/18639	0.0298507462686567	0.90322736964528	0.654350961363997	0.833649632822227
GO:0042054	histone methyltransferase activity	2/616	67/18639	0.0298507462686567	0.90322736964528	0.654350961363997	0.833649632822227
GO:0016247	channel regulator activity	5/616	168/18639	0.0297619047619048	0.900539192949907	0.655645435354575	0.833649632822227
GO:0015106	bicarbonate transmembrane transporter activity	1/616	32/18639	0.03125	0.945566152597403	0.659162220954843	0.833649632822227
GO:0022884	macromolecule transmembrane transporter activity	1/616	32/18639	0.03125	0.945566152597403	0.659162220954843	0.833649632822227
GO:0030515	snoRNA binding	1/616	32/18639	0.03125	0.945566152597403	0.659162220954843	0.833649632822227
GO:0031369	translation initiation factor binding	1/616	32/18639	0.03125	0.945566152597403	0.659162220954843	0.833649632822227
GO:0042910	xenobiotic transmembrane transporter activity	1/616	32/18639	0.03125	0.945566152597403	0.659162220954843	0.833649632822227
GO:0070717	poly-purine tract binding	1/616	32/18639	0.03125	0.945566152597403	0.659162220954843	0.833649632822227
GO:0160041	neuropeptide activity	1/616	32/18639	0.03125	0.945566152597403	0.659162220954843	0.833649632822227
GO:0008238	exopeptidase activity	3/616	102/18639	0.0294117647058824	0.88994461420932	0.659856454073334	0.833649632822227
GO:0003777	microtubule motor activity	2/616	68/18639	0.0294117647058824	0.88994461420932	0.662326736637019	0.834420060060963
GO:0030145	manganese ion binding	2/616	68/18639	0.0294117647058824	0.88994461420932	0.662326736637019	0.834420060060963
GO:0141108	transporter regulator activity	5/616	170/18639	0.0294117647058824	0.88994461420932	0.665833996401494	0.837662124505105
GO:0016279	protein-lysine N-methyltransferase activity	2/616	69/18639	0.0289855072463768	0.877046866177301	0.670153920062372	0.839930173071701
GO:0019956	chemokine binding	1/616	33/18639	0.0303030303030303	0.916912632821724	0.670445935250098	0.839930173071701
GO:0140416	transcription regulator inhibitor activity	1/616	33/18639	0.0303030303030303	0.916912632821724	0.670445935250098	0.839930173071701
GO:0016278	lysine N-methyltransferase activity	2/616	70/18639	0.0285714285714286	0.864517625231911	0.677833604630627	0.847679530286555
GO:0140767	enzyme-substrate adaptor activity	4/616	139/18639	0.0287769784172662	0.870737176492572	0.678629243109294	0.847679530286555
GO:0005244	voltage-gated monoatomic ion channel activity	5/616	173/18639	0.0289017341040462	0.874512048644997	0.68074436021775	0.847679530286555
GO:0015020	glucuronosyltransferase activity	1/616	34/18639	0.0294117647058824	0.88994461420932	0.681356679305024	0.847679530286555
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/616	34/18639	0.0294117647058824	0.88994461420932	0.681356679305024	0.847679530286555
GO:0140299	molecular sensor activity	2/616	71/18639	0.028169014084507	0.85234132065118	0.685366973358476	0.85148777715035
GO:0022832	voltage-gated channel activity	5/616	175/18639	0.0285714285714286	0.864517625231911	0.690433949140807	0.856055676372069
GO:0043015	gamma-tubulin binding	1/616	35/18639	0.0285714285714286	0.864517625231911	0.691906761839187	0.856055676372069
GO:0061631	ubiquitin conjugating enzyme activity	1/616	35/18639	0.0285714285714286	0.864517625231911	0.691906761839187	0.856055676372069
GO:0004033	aldo-keto reductase (NADPH) activity	1/616	36/18639	0.0277777777777778	0.840503246753247	0.702108086001037	0.85919638900809
GO:0016409	palmitoyltransferase activity	1/616	36/18639	0.0277777777777778	0.840503246753247	0.702108086001037	0.85919638900809
GO:0044390	ubiquitin-like protein conjugating enzyme binding	1/616	36/18639	0.0277777777777778	0.840503246753247	0.702108086001037	0.85919638900809
GO:0045505	dynein intermediate chain binding	1/616	36/18639	0.0277777777777778	0.840503246753247	0.702108086001037	0.85919638900809
GO:0055106	ubiquitin-protein transferase regulator activity	1/616	36/18639	0.0277777777777778	0.840503246753247	0.702108086001037	0.85919638900809
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	1/616	36/18639	0.0277777777777778	0.840503246753247	0.702108086001037	0.85919638900809
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	1/616	36/18639	0.0277777777777778	0.840503246753247	0.702108086001037	0.85919638900809
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	1/616	36/18639	0.0277777777777778	0.840503246753247	0.702108086001037	0.85919638900809
GO:0003678	DNA helicase activity	2/616	74/18639	0.027027027027027	0.817786942786943	0.707102218041062	0.862953319160317
GO:0035064	methylated histone binding	2/616	74/18639	0.027027027027027	0.817786942786943	0.707102218041062	0.862953319160317
GO:0019213	deacetylase activity	1/616	37/18639	0.027027027027027	0.817786942786943	0.711972162710351	0.866538710924266
GO:0023023	MHC protein complex binding	1/616	37/18639	0.027027027027027	0.817786942786943	0.711972162710351	0.866538710924266
GO:0019003	GDP binding	2/616	75/18639	0.0266666666666667	0.806883116883117	0.71406371244417	0.867906707401654
GO:0015293	symporter activity	4/616	146/18639	0.0273972602739726	0.828989503647038	0.71524485206565	0.868165943576304
GO:0140034	methylation-dependent protein binding	2/616	76/18639	0.0263157894736842	0.796266233766234	0.7208859197971	0.871055963439437
GO:0005501	retinoid binding	1/616	38/18639	0.0263157894736842	0.796266233766234	0.721510123562432	0.871055963439437
GO:0019840	isoprenoid binding	1/616	38/18639	0.0263157894736842	0.796266233766234	0.721510123562432	0.871055963439437
GO:0042162	telomeric DNA binding	1/616	38/18639	0.0263157894736842	0.796266233766234	0.721510123562432	0.871055963439437
GO:0015631	tubulin binding	11/616	385/18639	0.0285714285714286	0.864517625231911	0.730630655664734	0.879821827889494
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	1/616	39/18639	0.0256410256410256	0.775849150849151	0.730732733308443	0.879821827889494
GO:0015291	secondary active transmembrane transporter activity	8/616	287/18639	0.0278745644599303	0.843431829494547	0.736135822617527	0.884498031619489
GO:0032451	demethylase activity	1/616	40/18639	0.025	0.756452922077922	0.739650401925754	0.884498031619489
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	1/616	40/18639	0.025	0.756452922077922	0.739650401925754	0.884498031619489
GO:0071855	neuropeptide receptor binding	1/616	40/18639	0.025	0.756452922077922	0.739650401925754	0.884498031619489
GO:0016835	carbon-oxygen lyase activity	2/616	79/18639	0.0253164556962025	0.766028275521946	0.740532911645748	0.884498031619489
GO:0033293	monocarboxylic acid binding	2/616	79/18639	0.0253164556962025	0.766028275521946	0.740532911645748	0.884498031619489
GO:0000049	tRNA binding	2/616	80/18639	0.025	0.756452922077922	0.746814280721069	0.885319176177467
GO:0008137	NADH dehydrogenase (ubiquinone) activity	1/616	41/18639	0.024390243902439	0.738002850807729	0.748273196291781	0.885319176177467
GO:0061650	ubiquitin-like protein conjugating enzyme activity	1/616	41/18639	0.024390243902439	0.738002850807729	0.748273196291781	0.885319176177467
GO:0033192	calmodulin-dependent protein phosphatase activity	2/616	81/18639	0.0246913580246914	0.747113997113997	0.752964719482249	0.885319176177467
GO:0140791	histone H2AXS140 phosphatase activity	2/616	81/18639	0.0246913580246914	0.747113997113997	0.752964719482249	0.885319176177467
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	2/616	81/18639	0.0246913580246914	0.747113997113997	0.752964719482249	0.885319176177467
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	2/616	81/18639	0.0246913580246914	0.747113997113997	0.752964719482249	0.885319176177467
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	2/616	81/18639	0.0246913580246914	0.747113997113997	0.752964719482249	0.885319176177467
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	2/616	81/18639	0.0246913580246914	0.747113997113997	0.752964719482249	0.885319176177467
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	2/616	81/18639	0.0246913580246914	0.747113997113997	0.752964719482249	0.885319176177467
GO:1990439	MAP kinase serine/threonine phosphatase activity	2/616	81/18639	0.0246913580246914	0.747113997113997	0.752964719482249	0.885319176177467
GO:0004520	DNA endonuclease activity	1/616	42/18639	0.0238095238095238	0.720431354359926	0.756610851474288	0.885319176177467
GO:0016859	cis-trans isomerase activity	1/616	42/18639	0.0238095238095238	0.720431354359926	0.756610851474288	0.885319176177467
GO:0019894	kinesin binding	1/616	42/18639	0.0238095238095238	0.720431354359926	0.756610851474288	0.885319176177467
GO:0048487	beta-tubulin binding	1/616	42/18639	0.0238095238095238	0.720431354359926	0.756610851474288	0.885319176177467
GO:0004386	helicase activity	4/616	155/18639	0.0258064516129032	0.780854629241726	0.757692429495885	0.885319176177467
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	2/616	82/18639	0.024390243902439	0.738002850807729	0.758986004994952	0.885319176177467
GO:0033549	MAP kinase phosphatase activity	2/616	82/18639	0.024390243902439	0.738002850807729	0.758986004994952	0.885319176177467
GO:0008375	acetylglucosaminyltransferase activity	1/616	43/18639	0.0232558139534884	0.703677136816672	0.76467278165076	0.888727080563584
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	2/616	83/18639	0.0240963855421687	0.729111250195588	0.764879940016819	0.888727080563584
GO:0005254	chloride channel activity	2/616	83/18639	0.0240963855421687	0.729111250195588	0.764879940016819	0.888727080563584
GO:0017018	myosin phosphatase activity	2/616	84/18639	0.0238095238095238	0.720431354359926	0.77064834936668	0.8940695191356
GO:0003954	NADH dehydrogenase activity	1/616	44/18639	0.0227272727272727	0.687684474616293	0.772468090668997	0.8940695191356
GO:0016790	thiolester hydrolase activity	1/616	44/18639	0.0227272727272727	0.687684474616293	0.772468090668997	0.8940695191356
GO:0008009	chemokine activity	1/616	45/18639	0.0222222222222222	0.672402597402597	0.780005582260709	0.900469764849236
GO:0046915	transition metal ion transmembrane transporter activity	1/616	45/18639	0.0222222222222222	0.672402597402597	0.780005582260709	0.900469764849236
GO:0005267	potassium channel activity	3/616	124/18639	0.0241935483870968	0.732051214914118	0.781783795259058	0.901362550575032
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/616	46/18639	0.0217391304347826	0.657785149632976	0.787293769919492	0.905387835407416
GO:0030276	clathrin binding	1/616	46/18639	0.0217391304347826	0.657785149632976	0.787293769919492	0.905387835407416
GO:0061749	forked DNA-dependent helicase activity	1/616	47/18639	0.0212765957446809	0.643789720917381	0.794340886454187	0.910818680894526
GO:1990518	single-stranded 3'-5' DNA helicase activity	1/616	47/18639	0.0212765957446809	0.643789720917381	0.794340886454187	0.910818680894526
GO:0015081	sodium ion transmembrane transporter activity	4/616	164/18639	0.024390243902439	0.738002850807729	0.795080364242469	0.910818680894526
GO:0003727	single-stranded RNA binding	2/616	89/18639	0.0224719101123595	0.679957682766672	0.797672509678334	0.910818680894526
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	3/616	128/18639	0.0234375	0.709174614448052	0.799582248514631	0.910818680894526
GO:0009378	four-way junction helicase activity	1/616	48/18639	0.0208333333333333	0.630377435064935	0.801154893228295	0.910818680894526
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	1/616	48/18639	0.0208333333333333	0.630377435064935	0.801154893228295	0.910818680894526
GO:0036121	double-stranded DNA helicase activity	1/616	48/18639	0.0208333333333333	0.630377435064935	0.801154893228295	0.910818680894526
GO:0043138	3'-5' DNA helicase activity	1/616	48/18639	0.0208333333333333	0.630377435064935	0.801154893228295	0.910818680894526
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	4/616	167/18639	0.0239520958083832	0.724745314565674	0.806464003580059	0.915693938242169
GO:0060590	ATPase regulator activity	1/616	49/18639	0.0204081632653061	0.617512589451365	0.807743489095724	0.915987243639525
GO:0016887	ATP hydrolysis activity	11/616	417/18639	0.026378896882494	0.798175745118191	0.81683811749392	0.924353972794248
GO:0003743	translation initiation factor activity	1/616	51/18639	0.0196078431372549	0.59329640947288	0.820273982546512	0.924353972794248
GO:0005272	sodium channel activity	1/616	51/18639	0.0196078431372549	0.59329640947288	0.820273982546512	0.924353972794248
GO:0016830	carbon-carbon lyase activity	1/616	51/18639	0.0196078431372549	0.59329640947288	0.820273982546512	0.924353972794248
GO:0030544	Hsp70 protein binding	1/616	51/18639	0.0196078431372549	0.59329640947288	0.820273982546512	0.924353972794248
GO:0051087	protein-folding chaperone binding	3/616	134/18639	0.0223880597014925	0.67742052723396	0.823988334254971	0.927374574437527
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	1/616	52/18639	0.0192307692307692	0.581886863136863	0.826230041657301	0.927705487471528
GO:0008276	protein methyltransferase activity	2/616	95/18639	0.0210526315789474	0.637012987012987	0.826350818829154	0.927705487471528
GO:0140030	modification-dependent protein binding	4/616	173/18639	0.023121387283237	0.699609638915997	0.827686929812409	0.928043970052164
GO:0022804	active transmembrane transporter activity	12/616	457/18639	0.0262582056892779	0.794523856887095	0.829697914520741	0.929137364950193
GO:0099094	ligand-gated monoatomic cation channel activity	3/616	136/18639	0.0220588235294118	0.66745846065699	0.831540294908271	0.930039457023341
GO:0051287	NAD binding	1/616	54/18639	0.0185185185185185	0.560335497835498	0.837557454419628	0.935602785323047
GO:0042626	ATPase-coupled transmembrane transporter activity	2/616	98/18639	0.0204081632653061	0.617512589451365	0.839274439892955	0.936354692268633
GO:0043021	ribonucleoprotein complex binding	4/616	177/18639	0.0225988700564972	0.683799251595862	0.840736098851739	0.936820224434795
GO:0016741	transferase activity, transferring one-carbon groups	5/616	215/18639	0.0232558139534884	0.703677136816672	0.842495889735631	0.93761639341546
GO:0043130	ubiquitin binding	2/616	100/18639	0.02	0.605162337662338	0.847400062504512	0.941905645683454
GO:0016853	isomerase activity	4/616	180/18639	0.0222222222222222	0.672402597402597	0.849970439290295	0.943593420845785
GO:0016504	peptidase activator activity	1/616	57/18639	0.0175438596491228	0.530844155844156	0.853181286975779	0.944921464776945
GO:0008408	3'-5' exonuclease activity	1/616	58/18639	0.0172413793103448	0.521691670398567	0.858048380250073	0.944921464776945
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	1/616	58/18639	0.0172413793103448	0.521691670398567	0.858048380250073	0.944921464776945
GO:0017116	single-stranded DNA helicase activity	1/616	58/18639	0.0172413793103448	0.521691670398567	0.858048380250073	0.944921464776945
GO:0004722	protein serine/threonine phosphatase activity	2/616	103/18639	0.0194174757281553	0.587536250157609	0.858889737878727	0.944921464776945
GO:0005253	monoatomic anion channel activity	2/616	103/18639	0.0194174757281553	0.587536250157609	0.858889737878727	0.944921464776945
GO:0004879	nuclear receptor activity	1/616	59/18639	0.0169491525423729	0.512849438696896	0.862754380883298	0.944921464776945
GO:0015459	potassium channel regulator activity	1/616	59/18639	0.0169491525423729	0.512849438696896	0.862754380883298	0.944921464776945
GO:0031593	polyubiquitin modification-dependent protein binding	1/616	59/18639	0.0169491525423729	0.512849438696896	0.862754380883298	0.944921464776945
GO:0036002	pre-mRNA binding	1/616	59/18639	0.0169491525423729	0.512849438696896	0.862754380883298	0.944921464776945
GO:0070888	E-box binding	1/616	59/18639	0.0169491525423729	0.512849438696896	0.862754380883298	0.944921464776945
GO:0098531	ligand-modulated transcription factor activity	1/616	60/18639	0.0166666666666667	0.504301948051948	0.867304612388997	0.948746630869427
GO:0004497	monooxygenase activity	2/616	106/18639	0.0188679245283019	0.570907865719187	0.869583583356385	0.949126321080115
GO:0008234	cysteine-type peptidase activity	4/616	187/18639	0.0213903743315508	0.647232446697687	0.869767933029938	0.949126321080115
GO:0008509	monoatomic anion transmembrane transporter activity	3/616	149/18639	0.0201342281879195	0.609223829861414	0.874135586323871	0.95273343977219
GO:0000510	H3-H4 histone complex chaperone activity	3/616	151/18639	0.0198675496688742	0.601154640061925	0.879767715887389	0.953410604383878
GO:0140584	chromatin extrusion motor activity	3/616	151/18639	0.0198675496688742	0.601154640061925	0.879767715887389	0.953410604383878
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	3/616	151/18639	0.0198675496688742	0.601154640061925	0.879767715887389	0.953410604383878
GO:0140849	ATP-dependent H2AZ histone chaperone activity	3/616	151/18639	0.0198675496688742	0.601154640061925	0.879767715887389	0.953410604383878
GO:1901682	sulfur compound transmembrane transporter activity	1/616	63/18639	0.0158730158730159	0.480287569573284	0.88007132712358	0.953410604383878
GO:0015616	DNA translocase activity	3/616	152/18639	0.0197368421052632	0.597199675324675	0.882498958719095	0.953736826471119
GO:0140674	ATP-dependent histone chaperone activity	3/616	152/18639	0.0197368421052632	0.597199675324675	0.882498958719095	0.953736826471119
GO:0004536	DNA nuclease activity	1/616	64/18639	0.015625	0.472783076298701	0.884048290005356	0.954261511594229
GO:0061775	cohesin loader activity	3/616	153/18639	0.0196078431372549	0.59329640947288	0.885174846865662	0.954329131777042
GO:0140658	ATP-dependent chromatin remodeler activity	3/616	158/18639	0.0189873417721519	0.57452120664146	0.897754865323069	0.966568288944135
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	1/616	68/18639	0.0147058823529412	0.44497230710466	0.898682221827657	0.966568288944135
GO:0061630	ubiquitin protein ligase activity	8/616	353/18639	0.0226628895184136	0.685736359957323	0.900947866607074	0.967120353310514
GO:0003689	DNA clamp loader activity	3/616	160/18639	0.01875	0.567339691558442	0.902430028674359	0.967120353310514
GO:0015079	potassium ion transmembrane transporter activity	3/616	160/18639	0.01875	0.567339691558442	0.902430028674359	0.967120353310514
GO:0008028	monocarboxylic acid transmembrane transporter activity	1/616	70/18639	0.0142857142857143	0.432258812615955	0.905292342691461	0.968209799486099
GO:0008168	methyltransferase activity	4/616	204/18639	0.0196078431372549	0.59329640947288	0.908715577731295	0.968209799486099
GO:0032182	ubiquitin-like protein binding	2/616	120/18639	0.0166666666666667	0.504301948051948	0.91029180161406	0.968209799486099
GO:0140713	histone chaperone activity	3/616	164/18639	0.0182926829268293	0.553502138105797	0.911205937885198	0.968209799486099
GO:0003697	single-stranded DNA binding	2/616	121/18639	0.0165289256198347	0.500134163357304	0.912690057227701	0.968209799486099
GO:0015108	chloride transmembrane transporter activity	2/616	121/18639	0.0165289256198347	0.500134163357304	0.912690057227701	0.968209799486099
GO:0015103	inorganic anion transmembrane transporter activity	3/616	165/18639	0.0181818181818182	0.550147579693034	0.913285058815791	0.968209799486099
GO:0008528	G protein-coupled peptide receptor activity	2/616	122/18639	0.0163934426229508	0.496034703001916	0.915028116858555	0.968209799486099
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2/616	122/18639	0.0163934426229508	0.496034703001916	0.915028116858555	0.968209799486099
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	2/616	122/18639	0.0163934426229508	0.496034703001916	0.915028116858555	0.968209799486099
GO:0015399	primary active transmembrane transporter activity	3/616	166/18639	0.0180722891566265	0.546833437646691	0.915319855032567	0.968209799486099
GO:0031491	nucleosome binding	1/616	74/18639	0.0135135135135135	0.408893471393471	0.917248792990164	0.968499403943484
GO:0140104	molecular carrier activity	5/616	249/18639	0.0200803212851406	0.607592708496323	0.917753058363391	0.968499403943484
GO:0003724	RNA helicase activity	1/616	77/18639	0.012987012987013	0.392962556923596	0.925216146425601	0.974646542394151
GO:0042826	histone deacetylase binding	2/616	127/18639	0.015748031496063	0.47650577768688	0.925861944036585	0.974646542394151
GO:0001653	peptide receptor activity	2/616	128/18639	0.015625	0.472783076298701	0.927866383648045	0.974646542394151
GO:0061659	ubiquitin-like protein ligase activity	8/616	372/18639	0.021505376344086	0.650712191034772	0.92797006079917	0.974646542394151
GO:0003823	antigen binding	3/616	174/18639	0.0172413793103448	0.521691670398567	0.930095960479904	0.974646542394151
GO:0008186	ATP-dependent activity, acting on RNA	1/616	79/18639	0.0126582278481013	0.383014137760973	0.930097480813148	0.974646542394151
GO:0046873	metal ion transmembrane transporter activity	10/616	450/18639	0.0222222222222222	0.672402597402597	0.931584947014507	0.975066158077028
GO:0005262	calcium channel activity	2/616	131/18639	0.0152671755725191	0.461955982948349	0.933577077613394	0.976012399323094
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	2/616	132/18639	0.0151515151515152	0.458456316410862	0.935383657415455	0.976762678348852
GO:0008135	translation factor activity, RNA binding	1/616	83/18639	0.0120481927710843	0.364555625097794	0.938926450416855	0.976893108777154
GO:0015297	antiporter activity	2/616	135/18639	0.0148148148148148	0.448268398268398	0.940528159044946	0.976893108777154
GO:0016755	aminoacyltransferase activity	11/616	496/18639	0.0221774193548387	0.671046947004608	0.940578869988948	0.976893108777154
GO:0004527	exonuclease activity	1/616	84/18639	0.0119047619047619	0.360215677179963	0.940953897417459	0.976893108777154
GO:0180051	translation factor activity	1/616	84/18639	0.0119047619047619	0.360215677179963	0.940953897417459	0.976893108777154
GO:0015276	ligand-gated monoatomic ion channel activity	3/616	186/18639	0.0161290322580645	0.488034143276079	0.947864025004791	0.982929514947165
GO:0022834	ligand-gated channel activity	3/616	188/18639	0.0159574468085106	0.482842290688035	0.950381643946006	0.983266821937217
GO:0140597	protein carrier chaperone	3/616	188/18639	0.0159574468085106	0.482842290688035	0.950381643946006	0.983266821937217
GO:0015085	calcium ion transmembrane transporter activity	2/616	147/18639	0.0136054421768707	0.411675059634243	0.957467895719138	0.989457030483948
GO:0016829	lyase activity	3/616	200/18639	0.015	0.453871753246753	0.963256730825718	0.993223280038195
GO:0004842	ubiquitin-protein transferase activity	9/616	449/18639	0.0200445434298441	0.606510137968935	0.963326927127346	0.993223280038195
GO:0003924	GTPase activity	6/616	331/18639	0.0181268882175227	0.548485502412995	0.964537348268006	0.993329507917797
GO:0005525	GTP binding	7/616	378/18639	0.0185185185185185	0.560335497835498	0.968653438530871	0.993953813205163
GO:0005261	monoatomic cation channel activity	6/616	341/18639	0.0175953079178886	0.532400883573904	0.971150974983686	0.993953813205163
GO:0008094	ATP-dependent activity, acting on DNA	3/616	210/18639	0.0142857142857143	0.432258812615955	0.971514606980157	0.993953813205163
GO:0000149	SNARE binding	1/616	106/18639	0.00943396226415094	0.285453932859593	0.971918170579226	0.993953813205163
GO:0004843	cysteine-type deubiquitinase activity	1/616	108/18639	0.00925925925925926	0.280167748917749	0.973753963579266	0.993953813205163
GO:0003730	mRNA 3'-UTR binding	4/616	262/18639	0.0152671755725191	0.461955982948349	0.975490438871017	0.993953813205163
GO:0043022	ribosome binding	1/616	112/18639	0.00892857142857143	0.270161757884972	0.977073871764949	0.993953813205163
GO:0019787	ubiquitin-like protein transferase activity	9/616	479/18639	0.0187891440501044	0.568524116801779	0.978809105553606	0.993953813205163
GO:0101005	deubiquitinase activity	1/616	115/18639	0.00869565217391304	0.26311405985319	0.979285593453471	0.993953813205163
GO:0019001	guanyl nucleotide binding	7/616	400/18639	0.0175	0.529517045454545	0.979828276082697	0.993953813205163
GO:0032561	guanyl ribonucleotide binding	7/616	400/18639	0.0175	0.529517045454545	0.979828276082697	0.993953813205163
GO:0009055	electron transfer activity	1/616	116/18639	0.00862068965517241	0.260845835199283	0.979974433576159	0.993953813205163
GO:0022836	gated channel activity	5/616	318/18639	0.0157232704402516	0.475756554765989	0.98124545796891	0.993953813205163
GO:0022853	active monoatomic ion transmembrane transporter activity	1/616	118/18639	0.00847457627118644	0.256424719348448	0.981284259447571	0.993953813205163
GO:0005216	monoatomic ion channel activity	8/616	448/18639	0.0178571428571429	0.540323515769944	0.982362208616449	0.993953813205163
GO:0004540	RNA nuclease activity	1/616	121/18639	0.00826446280991736	0.250067081678652	0.983090363315781	0.993953813205163
GO:0015078	proton transmembrane transporter activity	2/616	185/18639	0.0108108108108108	0.327114777114777	0.985720155750088	0.993953813205163
GO:0004519	endonuclease activity	1/616	127/18639	0.0078740157480315	0.23825288884344	0.986197205967219	0.993953813205163
GO:0019783	ubiquitin-like protein peptidase activity	1/616	127/18639	0.0078740157480315	0.23825288884344	0.986197205967219	0.993953813205163
GO:0140101	catalytic activity, acting on a tRNA	1/616	139/18639	0.00719424460431655	0.217684294123143	0.990805137437786	0.997411870609365
GO:0045182	translation regulator activity	5/616	356/18639	0.0140449438202247	0.42497355172917	0.992258807544049	0.997411870609365
GO:0004518	nuclease activity	2/616	209/18639	0.00956937799043062	0.289551357733176	0.992964103070416	0.997411870609365
GO:0003735	structural constituent of ribosome	1/616	175/18639	0.00571428571428571	0.172903525046382	0.997286181824507	0.999822228223907
GO:0140097	catalytic activity, acting on DNA	3/616	336/18639	0.00892857142857143	0.270161757884972	0.999091792591386	0.999822228223907
GO:0140098	catalytic activity, acting on RNA	3/616	387/18639	0.00775193798449612	0.234559045605557	0.99979376813406	0.999822228223907
GO:0030371	translation repressor activity	2/616	329/18639	0.0060790273556231	0.183939920262109	0.999822228223907	0.999822228223907