ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	100/2496	175/18639	0.571428571428571	4.26717032967033	1.39501935571287e-42	1.82189527856101e-39
GO:0009055	electron transfer activity	62/2496	116/18639	0.53448275862069	3.99127569628647	1.01412850363664e-24	6.62225912874727e-22
GO:0015078	proton transmembrane transporter activity	81/2496	185/18639	0.437837837837838	3.2695751039501	2.47300923623174e-24	1.07658335417288e-21
GO:0022853	active monoatomic ion transmembrane transporter activity	61/2496	118/18639	0.516949152542373	3.86034264993481	2.49143363822728e-23	8.13453082881207e-21
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	44/2496	68/18639	0.647058823529412	4.83194287330317	1.4978944332622e-22	3.91250025968088e-20
GO:0015399	primary active transmembrane transporter activity	67/2496	166/18639	0.403614457831325	3.01401036839666	4.43133345312981e-18	9.64553581631256e-16
GO:0003954	NADH dehydrogenase activity	27/2496	44/18639	0.613636363636364	4.5823590472028	1.57892259966426e-13	2.94581845023075e-11
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	31/2496	58/18639	0.53448275862069	3.99127569628647	4.69967892625984e-13	7.67222584711919e-11
GO:0008137	NADH dehydrogenase (ubiquinone) activity	25/2496	41/18639	0.609756097560976	4.55338297373358	1.55160412858086e-12	2.25154999102956e-10
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	15/2496	18/18639	0.833333333333333	6.22295673076923	4.2115906204277e-11	5.50033735027858e-09
GO:0016651	oxidoreductase activity, acting on NAD(P)H	34/2496	88/18639	0.386363636363636	2.88518902972028	2.77312179013055e-09	3.09380734646773e-07
GO:0022804	active transmembrane transporter activity	107/2496	457/18639	0.234135667396061	1.74841935280256	2.84270200288e-09	3.09380734646773e-07
GO:0016209	antioxidant activity	33/2496	86/18639	0.383720930232558	2.86545449463327	5.79387653962465e-09	5.82061750826907e-07
GO:0016675	oxidoreductase activity, acting on a heme group of donors	12/2496	16/18639	0.75	5.60066105769231	3.50001261355367e-08	3.26501176664363e-06
GO:0004129	cytochrome-c oxidase activity	11/2496	15/18639	0.733333333333333	5.47620192307692	1.97527704063454e-07	1.71980787671247e-05
GO:0031625	ubiquitin protein ligase binding	73/2496	302/18639	0.241721854304636	1.80506956826286	2.47680079870146e-07	2.02168865194007e-05
GO:0015252	proton channel activity	15/2496	27/18639	0.555555555555556	4.14863782051282	2.71379525060647e-07	2.08483329252473e-05
GO:0044389	ubiquitin-like protein ligase binding	76/2496	322/18639	0.236024844720497	1.76252687529861	3.91981041852667e-07	2.74526747649353e-05
GO:0004601	peroxidase activity	23/2496	57/18639	0.403508771929825	3.01322115384615	3.99388070852811e-07	2.74526747649353e-05
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	23/2496	59/18639	0.389830508474576	2.91107806388527	8.28232986983874e-07	5.27956153352334e-05
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	37/2496	122/18639	0.30327868852459	2.26474818726356	8.48934090382773e-07	5.27956153352334e-05
GO:0016829	lyase activity	52/2496	200/18639	0.26	1.9415625	1.29392959955362e-06	7.68123662280469e-05
GO:0019843	rRNA binding	24/2496	65/18639	0.369230769230769	2.75724852071006	1.52873981114449e-06	8.68058344936825e-05
GO:0016835	carbon-oxygen lyase activity	27/2496	79/18639	0.341772151898734	2.55219997565725	2.00700258983531e-06	0.000109214390930205
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	38/2496	132/18639	0.287878787878788	2.14974868881119	2.51204860328515e-06	0.000129926050420002
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	21/2496	54/18639	0.388888888888889	2.90404647435897	2.58658293332316e-06	0.000129926050420002
GO:0055105	ubiquitin-protein transferase inhibitor activity	10/2496	15/18639	0.666666666666667	4.97836538461539	2.8762123158595e-06	0.000139123454981945
GO:0045296	cadherin binding	75/2496	334/18639	0.224550898203593	1.67684462805159	3.44923868877701e-06	0.000160882347412242
GO:0016860	intramolecular oxidoreductase activity	20/2496	53/18639	0.377358490566038	2.81794267053701	7.65386515736729e-06	0.000344687858466265
GO:0033218	amide binding	58/2496	247/18639	0.234817813765182	1.75351331360947	1.05405032787549e-05	0.000458863242735129
GO:0015036	disulfide oxidoreductase activity	16/2496	40/18639	0.4	2.98701923076923	2.64370292010586e-05	0.00111376645601879
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	19/2496	54/18639	0.351851851851852	2.62747061965812	4.05431076820965e-05	0.00165466558227556
GO:0016853	isomerase activity	44/2496	180/18639	0.244444444444444	1.82540064102564	4.25076157741685e-05	0.00168227109700194
GO:0008135	translation factor activity, RNA binding	25/2496	83/18639	0.301204819277108	2.24926146895273	5.5263123361796e-05	0.00212275409148546
GO:0043021	ribonucleoprotein complex binding	43/2496	177/18639	0.242937853107345	1.81415009778357	6.02865536036319e-05	0.00224954968589552
GO:0180051	translation factor activity	25/2496	84/18639	0.297619047619048	2.2224845467033	6.87823139351399e-05	0.00249526949998035
GO:0042625	ATPase-coupled ion transmembrane transporter activity	11/2496	24/18639	0.458333333333333	3.42262620192308	0.000112796457510848	0.00377723521818377
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	11/2496	24/18639	0.458333333333333	3.42262620192308	0.000112796457510848	0.00377723521818377
GO:0046961	proton-transporting ATPase activity, rotational mechanism	11/2496	24/18639	0.458333333333333	3.42262620192308	0.000112796457510848	0.00377723521818377
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	7/2496	11/18639	0.636363636363636	4.75207604895105	0.000154127598474942	0.00479263437162557
GO:0070990	snRNP binding	7/2496	11/18639	0.636363636363636	4.75207604895105	0.000154127598474942	0.00479263437162557
GO:1990948	ubiquitin ligase inhibitor activity	7/2496	11/18639	0.636363636363636	4.75207604895105	0.000154127598474942	0.00479263437162557
GO:0044325	transmembrane transporter binding	34/2496	136/18639	0.25	1.86688701923077	0.000190170010394634	0.00577586124593935
GO:0003743	translation initiation factor activity	17/2496	51/18639	0.333333333333333	2.48918269230769	0.00021742278331109	0.00645350352282463
GO:1901681	sulfur compound binding	58/2496	275/18639	0.210909090909091	1.57497377622378	0.000255596222985099	0.0071418878081277
GO:0015035	protein-disulfide reductase activity	13/2496	34/18639	0.382352941176471	2.85523897058824	0.000256456507416854	0.0071418878081277
GO:0016836	hydro-lyase activity	19/2496	61/18639	0.311475409836066	2.32595759773014	0.000258756701147454	0.0071418878081277
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	8/2496	15/18639	0.533333333333333	3.98269230769231	0.000273426026344858	0.0071418878081277
GO:0031386	protein tag activity	8/2496	15/18639	0.533333333333333	3.98269230769231	0.000273426026344858	0.0071418878081277
GO:0141047	molecular tag activity	8/2496	15/18639	0.533333333333333	3.98269230769231	0.000273426026344858	0.0071418878081277
GO:0043022	ribosome binding	29/2496	112/18639	0.258928571428571	1.93356155563187	0.000289703161398686	0.00741867311346439
GO:0019887	protein kinase regulator activity	54/2496	255/18639	0.211764705882353	1.58136312217195	0.000368738223607001	0.00926100230828352
GO:0019205	nucleobase-containing compound kinase activity	15/2496	44/18639	0.340909090909091	2.54575502622378	0.000382670282467515	0.00942957337552027
GO:0004602	glutathione peroxidase activity	10/2496	23/18639	0.434782608695652	3.24676003344482	0.000393778587900941	0.00952360807034498
GO:0046875	ephrin receptor binding	11/2496	28/18639	0.392857142857143	2.93367960164835	0.000580847787598921	0.0135462001893605
GO:0051537	2 iron, 2 sulfur cluster binding	11/2496	28/18639	0.392857142857143	2.93367960164835	0.000580847787598921	0.0135462001893605
GO:0005528	FK506 binding	6/2496	10/18639	0.6	4.48052884615385	0.000742104363143974	0.0170033034783514
GO:0019207	kinase regulator activity	58/2496	287/18639	0.202090592334495	1.5091212141517	0.00078862237807994	0.0175248367531177
GO:0005126	cytokine receptor binding	56/2496	275/18639	0.203636363636364	1.52066433566434	0.000795662004670612	0.0175248367531177
GO:0015278	intracellularly gated calcium channel activity	8/2496	17/18639	0.470588235294118	3.51414027149321	0.000805122668596525	0.0175248367531177
GO:0002020	protease binding	32/2496	136/18639	0.235294117647059	1.75707013574661	0.000898004660990584	0.0189494248035555
GO:0005080	protein kinase C binding	16/2496	52/18639	0.307692307692308	2.29770710059172	0.000899589845191762	0.0189494248035555
GO:0005518	collagen binding	20/2496	72/18639	0.277777777777778	2.07431891025641	0.00094170064941895	0.0195216039387484
GO:0008106	alcohol dehydrogenase (NADP+) activity	11/2496	30/18639	0.366666666666667	2.73810096153846	0.00114436700640759	0.0233522392245049
GO:0005507	copper ion binding	18/2496	63/18639	0.285714285714286	2.13358516483516	0.0011656148841203	0.0234198929024787
GO:0005178	integrin binding	36/2496	161/18639	0.22360248447205	1.66976230291448	0.00120420684546439	0.0238286990935832
GO:0050750	low-density lipoprotein particle receptor binding	10/2496	26/18639	0.384615384615385	2.87213387573965	0.00124940009527012	0.0243539779764594
GO:0051087	protein-folding chaperone binding	31/2496	134/18639	0.23134328358209	1.7275670924225	0.00143474892430453	0.0275556190462017
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	13/2496	40/18639	0.325	2.426953125	0.00153002277401843	0.0285458534695438
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	13/2496	40/18639	0.325	2.426953125	0.00153002277401843	0.0285458534695438
GO:0070325	lipoprotein particle receptor binding	11/2496	31/18639	0.354838709677419	2.64977512406948	0.00156141937558802	0.028721319781943
GO:0038024	cargo receptor activity	18/2496	65/18639	0.276923076923077	2.06793639053254	0.00172430002132014	0.0297681671617643
GO:0004364	glutathione transferase activity	10/2496	27/18639	0.37037037037037	2.76575854700855	0.00174855749734393	0.0297681671617643
GO:0005044	scavenger receptor activity	10/2496	27/18639	0.37037037037037	2.76575854700855	0.00174855749734393	0.0297681671617643
GO:0004033	aldo-keto reductase (NADPH) activity	12/2496	36/18639	0.333333333333333	2.48918269230769	0.00180067779921851	0.0297681671617643
GO:0055106	ubiquitin-protein transferase regulator activity	12/2496	36/18639	0.333333333333333	2.48918269230769	0.00180067779921851	0.0297681671617643
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	12/2496	36/18639	0.333333333333333	2.48918269230769	0.00180067779921851	0.0297681671617643
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	12/2496	36/18639	0.333333333333333	2.48918269230769	0.00180067779921851	0.0297681671617643
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	12/2496	36/18639	0.333333333333333	2.48918269230769	0.00180067779921851	0.0297681671617643
GO:0098631	cell adhesion mediator activity	20/2496	76/18639	0.263157894736842	1.96514423076923	0.00193888440355822	0.0314915369662595
GO:0120227	acyl-CoA binding	8/2496	19/18639	0.421052631578947	3.14423076923077	0.00195315045502835	0.0314915369662595
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	17/2496	61/18639	0.278688524590164	2.08111995586381	0.00212410039029723	0.0338301842649779
GO:0008201	heparin binding	37/2496	172/18639	0.215116279069767	1.60639115608229	0.00215175639651624	0.0338577572753038
GO:0051540	metal cluster binding	20/2496	77/18639	0.25974025974026	1.93962287712288	0.00229548092954645	0.0356892630236627
GO:0051082	unfolded protein binding	28/2496	121/18639	0.231404958677686	1.72802765416402	0.00236261302209755	0.0363008541983459
GO:0016859	cis-trans isomerase activity	13/2496	42/18639	0.30952380952381	2.31138392857143	0.00250786104396456	0.0376878878751839
GO:0001540	amyloid-beta binding	21/2496	83/18639	0.253012048192771	1.8893796339203	0.00255989848777893	0.0376878878751839
GO:0004032	aldose reductase (NADPH) activity	6/2496	12/18639	0.5	3.73377403846154	0.00256831701446506	0.0376878878751839
GO:0005527	macrolide binding	6/2496	12/18639	0.5	3.73377403846154	0.00256831701446506	0.0376878878751839
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	11/2496	33/18639	0.333333333333333	2.48918269230769	0.00276712964156291	0.0401541256875684
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	12/2496	39/18639	0.307692307692308	2.29770710059172	0.00383340197023998	0.0544176410123198
GO:0016776	phosphotransferase activity, phosphate group as acceptor	12/2496	39/18639	0.307692307692308	2.29770710059172	0.00383340197023998	0.0544176410123198
GO:0035325	Toll-like receptor binding	6/2496	13/18639	0.461538461538462	3.44656065088757	0.00423260859973172	0.0586720889355695
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	6/2496	13/18639	0.461538461538462	3.44656065088757	0.00423260859973172	0.0586720889355695
GO:0004550	nucleoside diphosphate kinase activity	7/2496	17/18639	0.411764705882353	3.07487273755656	0.00435772789184551	0.0586720889355695
GO:0032977	membrane insertase activity	7/2496	17/18639	0.411764705882353	3.07487273755656	0.00435772789184551	0.0586720889355695
GO:1901567	fatty acid derivative binding	7/2496	17/18639	0.411764705882353	3.07487273755656	0.00435772789184551	0.0586720889355695
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	16/2496	60/18639	0.266666666666667	1.99134615384615	0.00457590379185751	0.0602231977443303
GO:0042626	ATPase-coupled transmembrane transporter activity	23/2496	98/18639	0.23469387755102	1.75258781397174	0.00459277908130116	0.0602231977443303
GO:0051536	iron-sulfur cluster binding	19/2496	76/18639	0.25	1.86688701923077	0.00461127088394566	0.0602231977443303
GO:0051213	dioxygenase activity	22/2496	93/18639	0.236559139784946	1.76651674937965	0.00497042618682224	0.064271055445444
GO:0005539	glycosaminoglycan binding	47/2496	242/18639	0.194214876033058	1.45030892403051	0.00520738691290512	0.0666749736103342
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	13/2496	46/18639	0.282608695652174	2.11039402173913	0.00598596971335822	0.0721144617552507
GO:0061650	ubiquitin-like protein conjugating enzyme activity	12/2496	41/18639	0.292682926829268	2.18562382739212	0.00600031822507037	0.0721144617552507
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	5/2496	10/18639	0.5	3.73377403846154	0.00601874144817942	0.0721144617552507
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	5/2496	10/18639	0.5	3.73377403846154	0.00601874144817942	0.0721144617552507
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	5/2496	10/18639	0.5	3.73377403846154	0.00601874144817942	0.0721144617552507
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	5/2496	10/18639	0.5	3.73377403846154	0.00601874144817942	0.0721144617552507
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	5/2496	10/18639	0.5	3.73377403846154	0.00601874144817942	0.0721144617552507
GO:0003746	translation elongation factor activity	7/2496	18/18639	0.388888888888889	2.90404647435897	0.00631630699411325	0.0743161885974045
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	7/2496	18/18639	0.388888888888889	2.90404647435897	0.00631630699411325	0.0743161885974045
GO:0043539	protein serine/threonine kinase activator activity	18/2496	73/18639	0.246575342465753	1.84131322444679	0.00667923703746356	0.0778846747404233
GO:0016504	peptidase activator activity	15/2496	57/18639	0.263157894736842	1.96514423076923	0.00677762186070107	0.0783325146024389
GO:0030145	manganese ion binding	17/2496	68/18639	0.25	1.86688701923077	0.00713784570268309	0.0817721621728431
GO:0005125	cytokine activity	45/2496	234/18639	0.192307692307692	1.43606693786982	0.00738183392203435	0.0838319574102336
GO:0008083	growth factor activity	33/2496	162/18639	0.203703703703704	1.5211672008547	0.00853204552783955	0.095950194026441
GO:0046625	sphingolipid binding	9/2496	28/18639	0.321428571428571	2.40028331043956	0.00859584433468117	0.095950194026441
GO:0050145	nucleoside monophosphate kinase activity	7/2496	19/18639	0.368421052631579	2.75120192307692	0.0088614816419128	0.0972528993641858
GO:0097001	ceramide binding	7/2496	19/18639	0.368421052631579	2.75120192307692	0.0088614816419128	0.0972528993641858
GO:0005041	low-density lipoprotein particle receptor activity	6/2496	15/18639	0.4	2.98701923076923	0.00973284770997085	0.102682549633692
GO:0016846	carbon-sulfur lyase activity	6/2496	15/18639	0.4	2.98701923076923	0.00973284770997085	0.102682549633692
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	5/2496	11/18639	0.454545454545455	3.39434003496503	0.00982796225437324	0.102682549633692
GO:0019864	IgG binding	5/2496	11/18639	0.454545454545455	3.39434003496503	0.00982796225437324	0.102682549633692
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	5/2496	11/18639	0.454545454545455	3.39434003496503	0.00982796225437324	0.102682549633692
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	5/2496	11/18639	0.454545454545455	3.39434003496503	0.00982796225437324	0.102682549633692
GO:0048027	mRNA 5'-UTR binding	8/2496	24/18639	0.333333333333333	2.48918269230769	0.0102707898701239	0.106331839028192
GO:0051219	phosphoprotein binding	21/2496	93/18639	0.225806451612903	1.68622053349876	0.0103400792929405	0.106331839028192
GO:0099604	ligand-gated calcium channel activity	9/2496	29/18639	0.310344827586207	2.3175149204244	0.0110124531141325	0.112361435680134
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	15/2496	60/18639	0.25	1.86688701923077	0.0111040321125294	0.112417565418321
GO:0016505	peptidase activator activity involved in apoptotic process	7/2496	20/18639	0.35	2.61364182692308	0.0120841042670034	0.12139877055928
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	20/2496	89/18639	0.224719101123595	1.67810069144339	0.0127913809532725	0.126557147916469
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	20/2496	89/18639	0.224719101123595	1.67810069144339	0.0127913809532725	0.126557147916469
GO:0015662	P-type ion transporter activity	8/2496	25/18639	0.32	2.38961538461538	0.0133666874246472	0.130275326690965
GO:0140358	P-type transmembrane transporter activity	8/2496	25/18639	0.32	2.38961538461538	0.0133666874246472	0.130275326690965
GO:0000062	fatty-acyl-CoA binding	6/2496	16/18639	0.375	2.80033052884615	0.0138356220677664	0.131564050520347
GO:0043023	ribosomal large subunit binding	6/2496	16/18639	0.375	2.80033052884615	0.0138356220677664	0.131564050520347
GO:0031072	heat shock protein binding	27/2496	131/18639	0.206106870229008	1.53911296241926	0.0139463560690148	0.131564050520347
GO:0004860	protein kinase inhibitor activity	19/2496	84/18639	0.226190476190476	1.68908825549451	0.0140026056832528	0.131564050520347
GO:0051117	ATPase binding	19/2496	84/18639	0.226190476190476	1.68908825549451	0.0140026056832528	0.131564050520347
GO:0140793	histone H2AXY142 phosphatase activity	20/2496	90/18639	0.222222222222222	1.65945512820513	0.0144327469779191	0.134636911094017
GO:0005165	neurotrophin receptor binding	5/2496	12/18639	0.416666666666667	3.11147836538462	0.0150134231400219	0.137115598747333
GO:0031543	peptidyl-proline dioxygenase activity	5/2496	12/18639	0.416666666666667	3.11147836538462	0.0150134231400219	0.137115598747333
GO:0141221	histone deacetylase activity, hydrolytic mechanism	5/2496	12/18639	0.416666666666667	3.11147836538462	0.0150134231400219	0.137115598747333
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	7/2496	21/18639	0.333333333333333	2.48918269230769	0.0160724190409065	0.145767911579332
GO:0140318	protein transporter activity	11/2496	41/18639	0.268292682926829	2.00348850844278	0.0164554842056266	0.148212843948609
GO:0048029	monosaccharide binding	17/2496	74/18639	0.22972972972973	1.7155178014553	0.0167428097718163	0.149767873712274
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	13/2496	52/18639	0.25	1.86688701923077	0.0173850299372797	0.154454755769302
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	26/2496	128/18639	0.203125	1.516845703125	0.0186498494464898	0.164572320115647
GO:0004029	aldehyde dehydrogenase (NAD+) activity	6/2496	17/18639	0.352941176470588	2.63560520361991	0.0190053825273596	0.165473530538211
GO:0051787	misfolded protein binding	6/2496	17/18639	0.352941176470588	2.63560520361991	0.0190053825273596	0.165473530538211
GO:0043394	proteoglycan binding	10/2496	37/18639	0.27027027027027	2.01825623700624	0.0206280083324844	0.178411780676984
GO:0031369	translation initiation factor binding	9/2496	32/18639	0.28125	2.10024789663462	0.021307848895396	0.179793484110004
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	5/2496	13/18639	0.384615384615385	2.87213387573965	0.0217514322277034	0.179793484110004
GO:0005172	vascular endothelial growth factor receptor binding	5/2496	13/18639	0.384615384615385	2.87213387573965	0.0217514322277034	0.179793484110004
GO:0019104	DNA N-glycosylase activity	5/2496	13/18639	0.384615384615385	2.87213387573965	0.0217514322277034	0.179793484110004
GO:0019855	calcium channel inhibitor activity	5/2496	13/18639	0.384615384615385	2.87213387573965	0.0217514322277034	0.179793484110004
GO:0070700	BMP receptor binding	5/2496	13/18639	0.384615384615385	2.87213387573965	0.0217514322277034	0.179793484110004
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	5/2496	13/18639	0.384615384615385	2.87213387573965	0.0217514322277034	0.179793484110004
GO:0019838	growth factor binding	27/2496	136/18639	0.198529411764706	1.4825279270362	0.022184586084779	0.18222056243221
GO:0008200	ion channel inhibitor activity	11/2496	43/18639	0.255813953488372	1.91030299642218	0.0233245989326597	0.18982645931294
GO:0003925	G protein activity	13/2496	54/18639	0.240740740740741	1.79774305555556	0.0235466205273325	0.18982645931294
GO:0050661	NADP binding	13/2496	54/18639	0.240740740740741	1.79774305555556	0.0235466205273325	0.18982645931294
GO:0000900	mRNA regulatory element binding translation repressor activity	6/2496	18/18639	0.333333333333333	2.48918269230769	0.0253499202939828	0.200648460023888
GO:0030228	lipoprotein particle receptor activity	6/2496	18/18639	0.333333333333333	2.48918269230769	0.0253499202939828	0.200648460023888
GO:1990381	ubiquitin-specific protease binding	6/2496	18/18639	0.333333333333333	2.48918269230769	0.0253499202939828	0.200648460023888
GO:0019955	cytokine binding	28/2496	144/18639	0.194444444444444	1.45202323717949	0.0259613143858559	0.204249858963421
GO:0017134	fibroblast growth factor binding	7/2496	23/18639	0.304347826086957	2.27273202341137	0.0266714906304139	0.20858063930132
GO:0098632	cell-cell adhesion mediator activity	13/2496	55/18639	0.236363636363636	1.76505681818182	0.0271726747740747	0.210885642933884
GO:0016248	channel inhibitor activity	11/2496	44/18639	0.25	1.86688701923077	0.0274506579622972	0.210885642933884
GO:0030020	extracellular matrix structural constituent conferring tensile strength	11/2496	44/18639	0.25	1.86688701923077	0.0274506579622972	0.210885642933884
GO:0019210	kinase inhibitor activity	19/2496	90/18639	0.211111111111111	1.57648237179487	0.0279335791424137	0.213340668771885
GO:0030295	protein kinase activator activity	27/2496	139/18639	0.194244604316547	1.45053092141671	0.0287033951798539	0.217945547121449
GO:0019763	immunoglobulin receptor activity	5/2496	14/18639	0.357142857142857	2.66698145604396	0.0301824849746796	0.226542099867422
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	5/2496	14/18639	0.357142857142857	2.66698145604396	0.0301824849746796	0.226542099867422
GO:0042277	peptide binding	44/2496	249/18639	0.176706827309237	1.31956672845227	0.0319930984068645	0.232679564253164
GO:0008009	chemokine activity	11/2496	45/18639	0.244444444444444	1.82540064102564	0.0320766891259058	0.232679564253164
GO:0141110	transporter inhibitor activity	11/2496	45/18639	0.244444444444444	1.82540064102564	0.0320766891259058	0.232679564253164
GO:0003785	actin monomer binding	8/2496	29/18639	0.275862068965517	2.06001326259947	0.0326386688005078	0.232679564253164
GO:0043236	laminin binding	8/2496	29/18639	0.275862068965517	2.06001326259947	0.0326386688005078	0.232679564253164
GO:0051861	glycolipid binding	8/2496	29/18639	0.275862068965517	2.06001326259947	0.0326386688005078	0.232679564253164
GO:0003756	protein disulfide isomerase activity	6/2496	19/18639	0.315789473684211	2.35817307692308	0.0329599689026305	0.232679564253164
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	6/2496	19/18639	0.315789473684211	2.35817307692308	0.0329599689026305	0.232679564253164
GO:0008301	DNA binding, bending	6/2496	19/18639	0.315789473684211	2.35817307692308	0.0329599689026305	0.232679564253164
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	6/2496	19/18639	0.315789473684211	2.35817307692308	0.0329599689026305	0.232679564253164
GO:0043395	heparan sulfate proteoglycan binding	6/2496	19/18639	0.315789473684211	2.35817307692308	0.0329599689026305	0.232679564253164
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	7/2496	24/18639	0.291666666666667	2.17803485576923	0.0334247203552392	0.233419783893344
GO:0048306	calcium-dependent protein binding	17/2496	80/18639	0.2125	1.58685396634615	0.0341957594665636	0.233419783893344
GO:0004725	protein tyrosine phosphatase activity	20/2496	98/18639	0.204081632653061	1.52398940345369	0.0342243739710413	0.233419783893344
GO:0005522	profilin binding	4/2496	10/18639	0.4	2.98701923076923	0.0344946541281894	0.233419783893344
GO:0008239	dipeptidyl-peptidase activity	4/2496	10/18639	0.4	2.98701923076923	0.0344946541281894	0.233419783893344
GO:0015203	polyamine transmembrane transporter activity	4/2496	10/18639	0.4	2.98701923076923	0.0344946541281894	0.233419783893344
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	4/2496	10/18639	0.4	2.98701923076923	0.0344946541281894	0.233419783893344
GO:0141109	transporter activator activity	4/2496	10/18639	0.4	2.98701923076923	0.0344946541281894	0.233419783893344
GO:0019209	kinase activator activity	28/2496	148/18639	0.189189189189189	1.41277936590437	0.035789233049701	0.240931641045925
GO:0016229	steroid dehydrogenase activity	9/2496	35/18639	0.257142857142857	1.92022664835165	0.0371522404966731	0.24807039746823
GO:0030291	protein serine/threonine kinase inhibitor activity	11/2496	46/18639	0.239130434782609	1.78571801839465	0.037229554290791	0.24807039746823
GO:0019003	GDP binding	16/2496	75/18639	0.213333333333333	1.59307692307692	0.0378635644300506	0.249746541139627
GO:0044183	protein folding chaperone	16/2496	75/18639	0.213333333333333	1.59307692307692	0.0378635644300506	0.249746541139627
GO:0005201	extracellular matrix structural constituent	31/2496	168/18639	0.18452380952381	1.37794041895604	0.0385212737911007	0.252807957644108
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	33/2496	181/18639	0.18232044198895	1.36148666595835	0.0390890214251748	0.255251309906392
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	8/2496	30/18639	0.266666666666667	1.99134615384615	0.0394513862895556	0.256174458790225
GO:0005523	tropomyosin binding	5/2496	15/18639	0.333333333333333	2.48918269230769	0.0404073036070339	0.256174458790225
GO:0031005	filamin binding	5/2496	15/18639	0.333333333333333	2.48918269230769	0.0404073036070339	0.256174458790225
GO:0034483	heparan sulfate sulfotransferase activity	5/2496	15/18639	0.333333333333333	2.48918269230769	0.0404073036070339	0.256174458790225
GO:0141050	histone H3K deacetylase activity	5/2496	15/18639	0.333333333333333	2.48918269230769	0.0404073036070339	0.256174458790225
GO:0141051	histone H4K deacetylase activity	5/2496	15/18639	0.333333333333333	2.48918269230769	0.0404073036070339	0.256174458790225
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	6/2496	20/18639	0.3	2.24026442307692	0.0419067680321849	0.2618486837269
GO:0031418	L-ascorbic acid binding	6/2496	20/18639	0.3	2.24026442307692	0.0419067680321849	0.2618486837269
GO:0042288	MHC class I protein binding	6/2496	20/18639	0.3	2.24026442307692	0.0419067680321849	0.2618486837269
GO:0004197	cysteine-type endopeptidase activity	18/2496	88/18639	0.204545454545455	1.52745301573427	0.0421043059591493	0.2618486837269
GO:0001784	phosphotyrosine residue binding	11/2496	47/18639	0.234042553191489	1.74772401800327	0.0429337742115119	0.264488250567144
GO:0005504	fatty acid binding	11/2496	47/18639	0.234042553191489	1.74772401800327	0.0429337742115119	0.264488250567144
GO:0043177	organic acid binding	34/2496	189/18639	0.17989417989418	1.34336843711844	0.0433823496448397	0.265996941953806
GO:0004857	enzyme inhibitor activity	68/2496	416/18639	0.163461538461538	1.22065689718935	0.0457661652514645	0.277110995875685
GO:0045309	protein phosphorylated amino acid binding	13/2496	59/18639	0.220338983050847	1.64539194915254	0.0457959413572004	0.277110995875685
GO:0120013	lipid transfer activity	14/2496	65/18639	0.215384615384615	1.6083949704142	0.0464980390105519	0.277110995875685
GO:0042056	chemoattractant activity	10/2496	42/18639	0.238095238095238	1.77798763736264	0.0470110139507104	0.277110995875685
GO:0051879	Hsp90 protein binding	10/2496	42/18639	0.238095238095238	1.77798763736264	0.0470110139507104	0.277110995875685
GO:0042578	phosphoric ester hydrolase activity	60/2496	363/18639	0.165289256198347	1.23430546726001	0.048005252150952	0.277110995875685
GO:0008432	JUN kinase binding	4/2496	11/18639	0.363636363636364	2.71547202797203	0.0485899066275129	0.277110995875685
GO:0008526	phosphatidylinositol transfer activity	4/2496	11/18639	0.363636363636364	2.71547202797203	0.0485899066275129	0.277110995875685
GO:0010854	adenylate cyclase regulator activity	4/2496	11/18639	0.363636363636364	2.71547202797203	0.0485899066275129	0.277110995875685
GO:0015217	ADP transmembrane transporter activity	4/2496	11/18639	0.363636363636364	2.71547202797203	0.0485899066275129	0.277110995875685
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	4/2496	11/18639	0.363636363636364	2.71547202797203	0.0485899066275129	0.277110995875685
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	4/2496	11/18639	0.363636363636364	2.71547202797203	0.0485899066275129	0.277110995875685
GO:0034713	type I transforming growth factor beta receptor binding	4/2496	11/18639	0.363636363636364	2.71547202797203	0.0485899066275129	0.277110995875685
GO:0048407	platelet-derived growth factor binding	4/2496	11/18639	0.363636363636364	2.71547202797203	0.0485899066275129	0.277110995875685
GO:0050786	RAGE receptor binding	4/2496	11/18639	0.363636363636364	2.71547202797203	0.0485899066275129	0.277110995875685
GO:0140031	phosphorylation-dependent protein binding	4/2496	11/18639	0.363636363636364	2.71547202797203	0.0485899066275129	0.277110995875685
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	11/2496	48/18639	0.229166666666667	1.71131310096154	0.0492111906858505	0.279433978416177
GO:0097602	cullin family protein binding	7/2496	26/18639	0.269230769230769	2.01049371301775	0.0501162647937503	0.282120007847577
GO:0120014	phospholipid transfer activity	7/2496	26/18639	0.269230769230769	2.01049371301775	0.0501162647937503	0.282120007847577
GO:0051287	NAD binding	12/2496	54/18639	0.222222222222222	1.65945512820513	0.0506763379893707	0.284048486755872
GO:0019213	deacetylase activity	9/2496	37/18639	0.243243243243243	1.81643061330561	0.0513209638958745	0.286432388239368
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	5/2496	16/18639	0.3125	2.33360877403846	0.0524853406703373	0.290448537777375
GO:0017070	U6 snRNA binding	5/2496	16/18639	0.3125	2.33360877403846	0.0524853406703373	0.290448537777375
GO:0140297	DNA-binding transcription factor binding	78/2496	488/18639	0.159836065573771	1.19358350409836	0.053369785818735	0.294096794427291
GO:0005506	iron ion binding	28/2496	154/18639	0.181818181818182	1.35773601398601	0.0554487776613618	0.299699301688558
GO:0022884	macromolecule transmembrane transporter activity	8/2496	32/18639	0.25	1.86688701923077	0.0557633463325571	0.299699301688558
GO:0030515	snoRNA binding	8/2496	32/18639	0.25	1.86688701923077	0.0557633463325571	0.299699301688558
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	8/2496	32/18639	0.25	1.86688701923077	0.0557633463325571	0.299699301688558
GO:0043425	bHLH transcription factor binding	8/2496	32/18639	0.25	1.86688701923077	0.0557633463325571	0.299699301688558
GO:0051059	NF-kappaB binding	8/2496	32/18639	0.25	1.86688701923077	0.0557633463325571	0.299699301688558
GO:0008374	O-acyltransferase activity	12/2496	55/18639	0.218181818181818	1.62928321678322	0.0572354998168953	0.305100256166797
GO:0140313	molecular sequestering activity	12/2496	55/18639	0.218181818181818	1.62928321678322	0.0572354998168953	0.305100256166797
GO:0031406	carboxylic acid binding	33/2496	187/18639	0.176470588235294	1.31780260180995	0.0576693423967555	0.306163256789279
GO:0020037	heme binding	26/2496	142/18639	0.183098591549296	1.36729753521127	0.0587870953229966	0.310833791464913
GO:0005109	frizzled binding	9/2496	38/18639	0.236842105263158	1.76862980769231	0.0595728626723062	0.313718381653355
GO:0008320	protein transmembrane transporter activity	7/2496	27/18639	0.259259259259259	1.93603098290598	0.0601291689887525	0.315376283932975
GO:0140789	histone phosphatase activity	25/2496	136/18639	0.183823529411765	1.37271104355204	0.0605003602114343	0.316053881744533
GO:0043178	alcohol binding	18/2496	92/18639	0.195652173913043	1.46104201505017	0.0612370480916687	0.3186278279192
GO:0034062	5'-3' RNA polymerase activity	6/2496	22/18639	0.272727272727273	2.03660402097902	0.0639895998931152	0.329017391576411
GO:0061133	endopeptidase activator activity	6/2496	22/18639	0.272727272727273	2.03660402097902	0.0639895998931152	0.329017391576411
GO:0097747	RNA polymerase activity	6/2496	22/18639	0.272727272727273	2.03660402097902	0.0639895998931152	0.329017391576411
GO:0140311	protein sequestering activity	8/2496	33/18639	0.242424242424242	1.81031468531469	0.0653148168662633	0.329667419972446
GO:0004300	enoyl-CoA hydratase activity	4/2496	12/18639	0.333333333333333	2.48918269230769	0.0653781483712585	0.329667419972446
GO:0010853	cyclase activator activity	4/2496	12/18639	0.333333333333333	2.48918269230769	0.0653781483712585	0.329667419972446
GO:0016801	hydrolase activity, acting on ether bonds	4/2496	12/18639	0.333333333333333	2.48918269230769	0.0653781483712585	0.329667419972446
GO:0016803	ether hydrolase activity	4/2496	12/18639	0.333333333333333	2.48918269230769	0.0653781483712585	0.329667419972446
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	5/2496	17/18639	0.294117647058824	2.19633766968326	0.0664353232299113	0.333709738993324
GO:0141108	transporter regulator activity	30/2496	170/18639	0.176470588235294	1.31780260180995	0.0676620751077283	0.338569617205721
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	9/2496	39/18639	0.230769230769231	1.72328032544379	0.0686277552077792	0.342091024050991
GO:0001618	virus receptor activity	16/2496	81/18639	0.197530864197531	1.47507122507123	0.0693716577315003	0.343179488626286
GO:0030971	receptor tyrosine kinase binding	16/2496	81/18639	0.197530864197531	1.47507122507123	0.0693716577315003	0.343179488626286
GO:0000287	magnesium ion binding	39/2496	230/18639	0.169565217391304	1.26623641304348	0.0700938674469178	0.345443739191225
GO:0046915	transition metal ion transmembrane transporter activity	10/2496	45/18639	0.222222222222222	1.65945512820513	0.0706174674347859	0.346715836352746
GO:0051019	mitogen-activated protein kinase binding	7/2496	28/18639	0.25	1.86688701923077	0.0712812865858799	0.347363284631191
GO:0097718	disordered domain specific binding	7/2496	28/18639	0.25	1.86688701923077	0.0712812865858799	0.347363284631191
GO:0003714	transcription corepressor activity	35/2496	204/18639	0.17156862745098	1.2811969739819	0.0722581340256129	0.350814583782344
GO:0070851	growth factor receptor binding	25/2496	139/18639	0.179856115107914	1.34308418649696	0.0745896557832474	0.359904343721134
GO:0046906	tetrapyrrole binding	27/2496	152/18639	0.177631578947368	1.32647235576923	0.0746815292101281	0.359904343721134
GO:0016831	carboxy-lyase activity	8/2496	34/18639	0.235294117647059	1.75707013574661	0.0758167431846039	0.363316163544065
GO:0140272	exogenous protein binding	16/2496	82/18639	0.195121951219512	1.45708255159475	0.0759458749215389	0.363316163544065
GO:0000295	adenine nucleotide transmembrane transporter activity	6/2496	23/18639	0.260869565217391	1.94805602006689	0.0771606972799509	0.36644316599133
GO:0140103	catalytic activity, acting on a glycoprotein	6/2496	23/18639	0.260869565217391	1.94805602006689	0.0771606972799509	0.36644316599133
GO:0016791	phosphatase activity	45/2496	273/18639	0.164835164835165	1.23091451817413	0.0803181868096389	0.37979260135037
GO:0061134	peptidase regulator activity	38/2496	226/18639	0.168141592920354	1.25560542886317	0.0805532546508825	0.37979260135037
GO:0030246	carbohydrate binding	46/2496	280/18639	0.164285714285714	1.22681146978022	0.081214442884836	0.38085831941327
GO:0008308	voltage-gated monoatomic anion channel activity	5/2496	18/18639	0.277777777777778	2.07431891025641	0.0822374012821916	0.38085831941327
GO:0017128	phospholipid scramblase activity	5/2496	18/18639	0.277777777777778	2.07431891025641	0.0822374012821916	0.38085831941327
GO:0031690	adrenergic receptor binding	5/2496	18/18639	0.277777777777778	2.07431891025641	0.0822374012821916	0.38085831941327
GO:0035615	clathrin adaptor activity	5/2496	18/18639	0.277777777777778	2.07431891025641	0.0822374012821916	0.38085831941327
GO:0016874	ligase activity	29/2496	167/18639	0.173652694610778	1.29675984569323	0.0840149422374852	0.384398426346336
GO:0005035	death receptor activity	4/2496	13/18639	0.307692307692308	2.29770710059172	0.0847677999906163	0.384398426346336
GO:0005542	folic acid binding	4/2496	13/18639	0.307692307692308	2.29770710059172	0.0847677999906163	0.384398426346336
GO:0008253	5'-nucleotidase activity	4/2496	13/18639	0.307692307692308	2.29770710059172	0.0847677999906163	0.384398426346336
GO:0017154	semaphorin receptor activity	4/2496	13/18639	0.307692307692308	2.29770710059172	0.0847677999906163	0.384398426346336
GO:0035673	oligopeptide transmembrane transporter activity	4/2496	13/18639	0.307692307692308	2.29770710059172	0.0847677999906163	0.384398426346336
GO:0061631	ubiquitin conjugating enzyme activity	8/2496	35/18639	0.228571428571429	1.70686813186813	0.0872728921291759	0.394388917372677
GO:0016247	channel regulator activity	29/2496	168/18639	0.172619047619048	1.28904103708791	0.0891091808396527	0.401298586815815
GO:0004721	phosphoprotein phosphatase activity	30/2496	175/18639	0.171428571428571	1.2801510989011	0.0910914256295815	0.408815813993929
GO:0005540	hyaluronic acid binding	6/2496	24/18639	0.25	1.86688701923077	0.0917393562548549	0.410313696126166
GO:0003924	GTPase activity	53/2496	331/18639	0.16012084592145	1.19571011503602	0.0937074159761886	0.417685615238575
GO:0001968	fibronectin binding	7/2496	30/18639	0.233333333333333	1.74242788461538	0.0970060976146587	0.425324177220572
GO:0031210	phosphatidylcholine binding	7/2496	30/18639	0.233333333333333	1.74242788461538	0.0970060976146587	0.425324177220572
GO:0033612	receptor serine/threonine kinase binding	7/2496	30/18639	0.233333333333333	1.74242788461538	0.0970060976146587	0.425324177220572
GO:0035091	phosphatidylinositol binding	46/2496	284/18639	0.161971830985915	1.20953243499458	0.0970714029015011	0.425324177220572
GO:0016798	hydrolase activity, acting on glycosyl bonds	23/2496	130/18639	0.176923076923077	1.32118158284024	0.0972562535462714	0.425324177220572
GO:1990782	protein tyrosine kinase binding	21/2496	117/18639	0.179487179487179	1.34032914201183	0.0973751370512643	0.425324177220572
GO:0015485	cholesterol binding	11/2496	54/18639	0.203703703703704	1.5211672008547	0.099731477854378	0.431743206831156
GO:0017069	snRNA binding	11/2496	54/18639	0.203703703703704	1.5211672008547	0.099731477854378	0.431743206831156
GO:0005346	purine ribonucleotide transmembrane transporter activity	5/2496	19/18639	0.263157894736842	1.96514423076923	0.0998364842748921	0.431743206831156
GO:0033293	monocarboxylic acid binding	15/2496	79/18639	0.189873417721519	1.41788887536514	0.100768315115218	0.434334717955364
GO:0050840	extracellular matrix binding	13/2496	67/18639	0.194029850746269	1.44892723880597	0.105942449523258	0.449103597909903
GO:0005347	ATP transmembrane transporter activity	4/2496	14/18639	0.285714285714286	2.13358516483516	0.106601925996991	0.449103597909903
GO:0008191	metalloendopeptidase inhibitor activity	4/2496	14/18639	0.285714285714286	2.13358516483516	0.106601925996991	0.449103597909903
GO:0008474	palmitoyl-(protein) hydrolase activity	4/2496	14/18639	0.285714285714286	2.13358516483516	0.106601925996991	0.449103597909903
GO:0032036	myosin heavy chain binding	4/2496	14/18639	0.285714285714286	2.13358516483516	0.106601925996991	0.449103597909903
GO:0034236	protein kinase A catalytic subunit binding	4/2496	14/18639	0.285714285714286	2.13358516483516	0.106601925996991	0.449103597909903
GO:0098599	palmitoyl hydrolase activity	4/2496	14/18639	0.285714285714286	2.13358516483516	0.106601925996991	0.449103597909903
GO:0001848	complement binding	6/2496	25/18639	0.24	1.79221153846154	0.107691237231678	0.450784473796705
GO:0120020	cholesterol transfer activity	6/2496	25/18639	0.24	1.79221153846154	0.107691237231678	0.450784473796705
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	55/2496	349/18639	0.157593123209169	1.17683422415693	0.110548016813685	0.461264249069243
GO:0016411	acylglycerol O-acyltransferase activity	7/2496	31/18639	0.225806451612903	1.68622053349876	0.111547613426732	0.462479946461306
GO:0017147	Wnt-protein binding	7/2496	31/18639	0.225806451612903	1.68622053349876	0.111547613426732	0.462479946461306
GO:0048156	tau protein binding	9/2496	43/18639	0.209302325581395	1.56297517889088	0.112991066217329	0.466982064809596
GO:0008081	phosphoric diester hydrolase activity	16/2496	87/18639	0.183908045977011	1.37334217506631	0.114822803457402	0.473055461562674
GO:0005548	phospholipid transporter activity	13/2496	68/18639	0.191176470588235	1.42761948529412	0.115761263358618	0.473931692621804
GO:0032934	sterol binding	13/2496	68/18639	0.191176470588235	1.42761948529412	0.115761263358618	0.473931692621804
GO:0016408	C-acyltransferase activity	5/2496	20/18639	0.25	1.86688701923077	0.119146389689128	0.484751354934582
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	5/2496	20/18639	0.25	1.86688701923077	0.119146389689128	0.484751354934582
GO:0032813	tumor necrosis factor receptor superfamily binding	10/2496	50/18639	0.2	1.49350961538462	0.124102918167107	0.502161938540776
GO:0015216	purine nucleotide transmembrane transporter activity	6/2496	26/18639	0.230769230769231	1.72328032544379	0.124963728963057	0.502161938540776
GO:0019865	immunoglobulin binding	6/2496	26/18639	0.230769230769231	1.72328032544379	0.124963728963057	0.502161938540776
GO:0051139	metal cation:proton antiporter activity	6/2496	26/18639	0.230769230769231	1.72328032544379	0.124963728963057	0.502161938540776
GO:0120015	sterol transfer activity	7/2496	32/18639	0.21875	1.63352614182692	0.1271672082131	0.508300913406523
GO:0043531	ADP binding	8/2496	38/18639	0.210526315789474	1.57211538461538	0.127269830538999	0.508300913406523
GO:0008252	nucleotidase activity	4/2496	15/18639	0.266666666666667	1.99134615384615	0.130672697775157	0.517147100891985
GO:0033130	acetylcholine receptor binding	4/2496	15/18639	0.266666666666667	1.99134615384615	0.130672697775157	0.517147100891985
GO:0050700	CARD domain binding	4/2496	15/18639	0.266666666666667	1.99134615384615	0.130672697775157	0.517147100891985
GO:0051015	actin filament binding	34/2496	209/18639	0.162679425837321	1.21481643356643	0.13116733956443	0.517536391151495
GO:0008238	exopeptidase activity	18/2496	102/18639	0.176470588235294	1.31780260180995	0.132686559361045	0.521114381908589
GO:0016830	carbon-carbon lyase activity	10/2496	51/18639	0.196078431372549	1.46422511312217	0.136895137561631	0.521114381908589
GO:0030544	Hsp70 protein binding	10/2496	51/18639	0.196078431372549	1.46422511312217	0.136895137561631	0.521114381908589
GO:0003680	minor groove of adenine-thymine-rich DNA binding	3/2496	10/18639	0.3	2.24026442307692	0.139821753530475	0.521114381908589
GO:0004090	carbonyl reductase (NADPH) activity	3/2496	10/18639	0.3	2.24026442307692	0.139821753530475	0.521114381908589
GO:0004862	cAMP-dependent protein kinase inhibitor activity	3/2496	10/18639	0.3	2.24026442307692	0.139821753530475	0.521114381908589
GO:0005031	tumor necrosis factor receptor activity	3/2496	10/18639	0.3	2.24026442307692	0.139821753530475	0.521114381908589
GO:0016303	1-phosphatidylinositol-3-kinase activity	3/2496	10/18639	0.3	2.24026442307692	0.139821753530475	0.521114381908589
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	3/2496	10/18639	0.3	2.24026442307692	0.139821753530475	0.521114381908589
GO:0030957	Tat protein binding	3/2496	10/18639	0.3	2.24026442307692	0.139821753530475	0.521114381908589
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	3/2496	10/18639	0.3	2.24026442307692	0.139821753530475	0.521114381908589
GO:0047429	nucleoside triphosphate diphosphatase activity	3/2496	10/18639	0.3	2.24026442307692	0.139821753530475	0.521114381908589
GO:0050308	sugar-phosphatase activity	3/2496	10/18639	0.3	2.24026442307692	0.139821753530475	0.521114381908589
GO:0070097	delta-catenin binding	3/2496	10/18639	0.3	2.24026442307692	0.139821753530475	0.521114381908589
GO:0097177	mitochondrial ribosome binding	3/2496	10/18639	0.3	2.24026442307692	0.139821753530475	0.521114381908589
GO:0001846	opsonin binding	5/2496	21/18639	0.238095238095238	1.77798763736264	0.140054477833013	0.521114381908589
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	5/2496	21/18639	0.238095238095238	1.77798763736264	0.140054477833013	0.521114381908589
GO:0005123	death receptor binding	5/2496	21/18639	0.238095238095238	1.77798763736264	0.140054477833013	0.521114381908589
GO:0072542	protein phosphatase activator activity	5/2496	21/18639	0.238095238095238	1.77798763736264	0.140054477833013	0.521114381908589
GO:0140312	cargo adaptor activity	5/2496	21/18639	0.238095238095238	1.77798763736264	0.140054477833013	0.521114381908589
GO:0140416	transcription regulator inhibitor activity	7/2496	33/18639	0.212121212121212	1.58402534965035	0.143819775114172	0.533604051986103
GO:0019001	guanyl nucleotide binding	61/2496	400/18639	0.1525	1.13880108173077	0.151797240928468	0.560020329527061
GO:0032561	guanyl ribonucleotide binding	61/2496	400/18639	0.1525	1.13880108173077	0.151797240928468	0.560020329527061
GO:0072341	modified amino acid binding	16/2496	91/18639	0.175824175824176	1.31297548605241	0.153125665522794	0.563329913162731
GO:1902936	phosphatidylinositol bisphosphate binding	19/2496	111/18639	0.171171171171171	1.27822895010395	0.154574908500583	0.567064130622924
GO:0008142	oxysterol binding	4/2496	16/18639	0.25	1.86688701923077	0.15673515014343	0.571393151273429
GO:0032451	demethylase activity	8/2496	40/18639	0.2	1.49350961538462	0.158380031210552	0.571393151273429
GO:0050997	quaternary ammonium group binding	8/2496	40/18639	0.2	1.49350961538462	0.158380031210552	0.571393151273429
GO:0061791	GTPase motor activity	8/2496	40/18639	0.2	1.49350961538462	0.158380031210552	0.571393151273429
GO:0140662	ATP-dependent protein folding chaperone	8/2496	40/18639	0.2	1.49350961538462	0.158380031210552	0.571393151273429
GO:1990606	membrane scission GTPase motor activity	8/2496	40/18639	0.2	1.49350961538462	0.158380031210552	0.571393151273429
GO:0042379	chemokine receptor binding	13/2496	72/18639	0.180555555555556	1.34830729166667	0.160051004963487	0.575830888381029
GO:0004407	histone deacetylase activity	5/2496	22/18639	0.227272727272727	1.69717001748252	0.162426500756512	0.578008201602192
GO:0033558	protein lysine deacetylase activity	5/2496	22/18639	0.227272727272727	1.69717001748252	0.162426500756512	0.578008201602192
GO:0140035	ubiquitin-like protein reader activity	5/2496	22/18639	0.227272727272727	1.69717001748252	0.162426500756512	0.578008201602192
GO:0140517	protein-RNA adaptor activity	5/2496	22/18639	0.227272727272727	1.69717001748252	0.162426500756512	0.578008201602192
GO:0050698	proteoglycan sulfotransferase activity	6/2496	28/18639	0.214285714285714	1.60018887362637	0.163180598692943	0.579113755143977
GO:0099106	ion channel regulator activity	26/2496	160/18639	0.1625	1.2134765625	0.17018047193581	0.599704504304817
GO:0005261	monoatomic cation channel activity	52/2496	341/18639	0.152492668621701	1.13874633431085	0.17379803012815	0.599704504304817
GO:0005225	volume-sensitive anion channel activity	3/2496	11/18639	0.272727272727273	2.03660402097902	0.174033696119086	0.599704504304817
GO:0005536	D-glucose binding	3/2496	11/18639	0.272727272727273	2.03660402097902	0.174033696119086	0.599704504304817
GO:0008046	axon guidance receptor activity	3/2496	11/18639	0.272727272727273	2.03660402097902	0.174033696119086	0.599704504304817
GO:0015173	aromatic amino acid transmembrane transporter activity	3/2496	11/18639	0.272727272727273	2.03660402097902	0.174033696119086	0.599704504304817
GO:0019203	carbohydrate phosphatase activity	3/2496	11/18639	0.272727272727273	2.03660402097902	0.174033696119086	0.599704504304817
GO:0019206	nucleoside kinase activity	3/2496	11/18639	0.272727272727273	2.03660402097902	0.174033696119086	0.599704504304817
GO:0032794	GTPase activating protein binding	3/2496	11/18639	0.272727272727273	2.03660402097902	0.174033696119086	0.599704504304817
GO:0034511	U3 snoRNA binding	3/2496	11/18639	0.272727272727273	2.03660402097902	0.174033696119086	0.599704504304817
GO:0042608	T cell receptor binding	3/2496	11/18639	0.272727272727273	2.03660402097902	0.174033696119086	0.599704504304817
GO:0042287	MHC protein binding	8/2496	41/18639	0.195121951219512	1.45708255159475	0.175155231610097	0.601701294855015
GO:0015085	calcium ion transmembrane transporter activity	24/2496	147/18639	0.163265306122449	1.21919152276295	0.175534604394916	0.601701294855015
GO:0005543	phospholipid binding	74/2496	497/18639	0.148893360160966	1.11186832533664	0.176277560247866	0.602666213831711
GO:0005216	monoatomic ion channel activity	67/2496	448/18639	0.149553571428571	1.11679848471841	0.17964670670477	0.606138525420618
GO:0005525	GTP binding	57/2496	378/18639	0.150793650793651	1.12605883699634	0.183768974619619	0.606138525420618
GO:0004629	phospholipase C activity	6/2496	29/18639	0.206896551724138	1.5450099469496	0.183946842272284	0.606138525420618
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	6/2496	29/18639	0.206896551724138	1.5450099469496	0.183946842272284	0.606138525420618
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	6/2496	29/18639	0.206896551724138	1.5450099469496	0.183946842272284	0.606138525420618
GO:0097472	cyclin-dependent protein kinase activity	6/2496	29/18639	0.206896551724138	1.5450099469496	0.183946842272284	0.606138525420618
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	4/2496	17/18639	0.235294117647059	1.75707013574661	0.184519712270667	0.606138525420618
GO:0005092	GDP-dissociation inhibitor activity	4/2496	17/18639	0.235294117647059	1.75707013574661	0.184519712270667	0.606138525420618
GO:0008429	phosphatidylethanolamine binding	4/2496	17/18639	0.235294117647059	1.75707013574661	0.184519712270667	0.606138525420618
GO:0030169	low-density lipoprotein particle binding	4/2496	17/18639	0.235294117647059	1.75707013574661	0.184519712270667	0.606138525420618
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	4/2496	17/18639	0.235294117647059	1.75707013574661	0.184519712270667	0.606138525420618
GO:0036041	long-chain fatty acid binding	4/2496	17/18639	0.235294117647059	1.75707013574661	0.184519712270667	0.606138525420618
GO:0045236	CXCR chemokine receptor binding	4/2496	17/18639	0.235294117647059	1.75707013574661	0.184519712270667	0.606138525420618
GO:0048038	quinone binding	4/2496	17/18639	0.235294117647059	1.75707013574661	0.184519712270667	0.606138525420618
GO:0038187	pattern recognition receptor activity	9/2496	48/18639	0.1875	1.40016526442308	0.185882339216071	0.606138525420618
GO:0005158	insulin receptor binding	5/2496	23/18639	0.217391304347826	1.62338001672241	0.186111446166668	0.606138525420618
GO:0031681	G-protein beta-subunit binding	5/2496	23/18639	0.217391304347826	1.62338001672241	0.186111446166668	0.606138525420618
GO:0042171	lysophosphatidic acid acyltransferase activity	5/2496	23/18639	0.217391304347826	1.62338001672241	0.186111446166668	0.606138525420618
GO:0071617	lysophospholipid acyltransferase activity	5/2496	23/18639	0.217391304347826	1.62338001672241	0.186111446166668	0.606138525420618
GO:0005496	steroid binding	18/2496	108/18639	0.166666666666667	1.24459134615385	0.192044337500432	0.622864919776579
GO:0008307	structural constituent of muscle	8/2496	42/18639	0.19047619047619	1.42239010989011	0.192677969057992	0.622864919776579
GO:0048487	beta-tubulin binding	8/2496	42/18639	0.19047619047619	1.42239010989011	0.192677969057992	0.622864919776579
GO:0003712	transcription coregulator activity	73/2496	495/18639	0.147474747474747	1.10127476689977	0.201572438058677	0.649754117713981
GO:0001222	transcription corepressor binding	9/2496	49/18639	0.183673469387755	1.37159046310832	0.202507238386784	0.649754117713981
GO:0019842	vitamin binding	24/2496	150/18639	0.16	1.19480769230769	0.20286788624656	0.649754117713981
GO:0001965	G-protein alpha-subunit binding	6/2496	30/18639	0.2	1.49350961538462	0.205682028436691	0.649754117713981
GO:0015215	nucleotide transmembrane transporter activity	6/2496	30/18639	0.2	1.49350961538462	0.205682028436691	0.649754117713981
GO:0016769	transferase activity, transferring nitrogenous groups	6/2496	30/18639	0.2	1.49350961538462	0.205682028436691	0.649754117713981
GO:1901981	phosphatidylinositol phosphate binding	29/2496	185/18639	0.156756756756757	1.17058861746362	0.20675704029402	0.649754117713981
GO:0004875	complement receptor activity	3/2496	12/18639	0.25	1.86688701923077	0.210252212035028	0.649754117713981
GO:0005049	nuclear export signal receptor activity	3/2496	12/18639	0.25	1.86688701923077	0.210252212035028	0.649754117713981
GO:0005247	voltage-gated chloride channel activity	3/2496	12/18639	0.25	1.86688701923077	0.210252212035028	0.649754117713981
GO:0008179	adenylate cyclase binding	3/2496	12/18639	0.25	1.86688701923077	0.210252212035028	0.649754117713981
GO:0008603	cAMP-dependent protein kinase regulator activity	3/2496	12/18639	0.25	1.86688701923077	0.210252212035028	0.649754117713981
GO:0035251	UDP-glucosyltransferase activity	3/2496	12/18639	0.25	1.86688701923077	0.210252212035028	0.649754117713981
GO:0045295	gamma-catenin binding	3/2496	12/18639	0.25	1.86688701923077	0.210252212035028	0.649754117713981
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	3/2496	12/18639	0.25	1.86688701923077	0.210252212035028	0.649754117713981
GO:0070008	serine-type exopeptidase activity	3/2496	12/18639	0.25	1.86688701923077	0.210252212035028	0.649754117713981
GO:0070679	inositol 1,4,5 trisphosphate binding	3/2496	12/18639	0.25	1.86688701923077	0.210252212035028	0.649754117713981
GO:0097371	MDM2/MDM4 family protein binding	3/2496	12/18639	0.25	1.86688701923077	0.210252212035028	0.649754117713981
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	5/2496	24/18639	0.208333333333333	1.55573918269231	0.210946206669776	0.649754117713981
GO:0070300	phosphatidic acid binding	5/2496	24/18639	0.208333333333333	1.55573918269231	0.210946206669776	0.649754117713981
GO:0004722	protein serine/threonine phosphatase activity	17/2496	103/18639	0.16504854368932	1.23250793502614	0.212068745117787	0.650696172454323
GO:0016854	racemase and epimerase activity	4/2496	18/18639	0.222222222222222	1.65945512820513	0.213743229695945	0.650696172454323
GO:0070628	proteasome binding	4/2496	18/18639	0.222222222222222	1.65945512820513	0.213743229695945	0.650696172454323
GO:0098641	cadherin binding involved in cell-cell adhesion	4/2496	18/18639	0.222222222222222	1.65945512820513	0.213743229695945	0.650696172454323
GO:1901611	phosphatidylglycerol binding	4/2496	18/18639	0.222222222222222	1.65945512820513	0.213743229695945	0.650696172454323
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	14/2496	83/18639	0.168674698795181	1.25958642261353	0.215671562797723	0.655039676776341
GO:0019208	phosphatase regulator activity	19/2496	117/18639	0.162393162393162	1.21267874753452	0.216251334457834	0.655276665433715
GO:0008194	UDP-glycosyltransferase activity	23/2496	145/18639	0.158620689655172	1.1845076259947	0.221383669237621	0.669275629685956
GO:0005164	tumor necrosis factor receptor binding	6/2496	31/18639	0.193548387096774	1.44533188585608	0.228274288039081	0.68851321057515
GO:0016790	thiolester hydrolase activity	8/2496	44/18639	0.181818181818182	1.35773601398601	0.229737152415146	0.690749621740674
GO:0003779	actin binding	65/2496	443/18639	0.146726862302483	1.09568989841986	0.230073572325569	0.690749621740674
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	5/2496	25/18639	0.2	1.49350961538462	0.236759949029301	0.707570923185966
GO:0019211	phosphatase activator activity	5/2496	25/18639	0.2	1.49350961538462	0.236759949029301	0.707570923185966
GO:0005048	signal sequence binding	9/2496	51/18639	0.176470588235294	1.31780260180995	0.237465686810311	0.70805978761248
GO:0042162	telomeric DNA binding	7/2496	38/18639	0.184210526315789	1.37560096153846	0.240366292985223	0.715076033345562
GO:0008381	mechanosensitive monoatomic ion channel activity	4/2496	19/18639	0.210526315789474	1.57211538461538	0.244118361808226	0.72130900570485
GO:0070003	threonine-type peptidase activity	4/2496	19/18639	0.210526315789474	1.57211538461538	0.244118361808226	0.72130900570485
GO:0140036	ubiquitin-modified protein reader activity	4/2496	19/18639	0.210526315789474	1.57211538461538	0.244118361808226	0.72130900570485
GO:0008035	high-density lipoprotein particle binding	3/2496	13/18639	0.230769230769231	1.72328032544379	0.247897535648352	0.724282285361851
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	3/2496	13/18639	0.230769230769231	1.72328032544379	0.247897535648352	0.724282285361851
GO:0030955	potassium ion binding	3/2496	13/18639	0.230769230769231	1.72328032544379	0.247897535648352	0.724282285361851
GO:0031432	titin binding	3/2496	13/18639	0.230769230769231	1.72328032544379	0.247897535648352	0.724282285361851
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	3/2496	13/18639	0.230769230769231	1.72328032544379	0.247897535648352	0.724282285361851
GO:0042605	peptide antigen binding	8/2496	45/18639	0.177777777777778	1.3275641025641	0.249148976943335	0.724696133380835
GO:0051539	4 iron, 4 sulfur cluster binding	8/2496	45/18639	0.177777777777778	1.3275641025641	0.249148976943335	0.724696133380835
GO:0016758	hexosyltransferase activity	30/2496	197/18639	0.152284263959391	1.1371900624756	0.25132848244086	0.725382645794822
GO:0071813	lipoprotein particle binding	6/2496	32/18639	0.1875	1.40016526442308	0.251606691075846	0.725382645794822
GO:0071814	protein-lipid complex binding	6/2496	32/18639	0.1875	1.40016526442308	0.251606691075846	0.725382645794822
GO:0140142	nucleocytoplasmic carrier activity	6/2496	32/18639	0.1875	1.40016526442308	0.251606691075846	0.725382645794822
GO:0030159	signaling receptor complex adaptor activity	9/2496	52/18639	0.173076923076923	1.29246024408284	0.255698977757055	0.735556971257079
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	14/2496	86/18639	0.162790697674419	1.21564736135957	0.256995993661938	0.73642091915017
GO:0001664	G protein-coupled receptor binding	44/2496	297/18639	0.148148148148148	1.10630341880342	0.25712705906009	0.73642091915017
GO:0036002	pre-mRNA binding	10/2496	59/18639	0.169491525423729	1.26568611473272	0.260668559539935	0.74291964199426
GO:0061135	endopeptidase regulator activity	28/2496	184/18639	0.152173913043478	1.13636601170569	0.26171225712411	0.74291964199426
GO:0015297	antiporter activity	21/2496	135/18639	0.155555555555556	1.16161858974359	0.263310373632894	0.74291964199426
GO:0005160	transforming growth factor beta receptor binding	5/2496	26/18639	0.192307692307692	1.43606693786982	0.263378096664121	0.74291964199426
GO:0008198	ferrous iron binding	5/2496	26/18639	0.192307692307692	1.43606693786982	0.263378096664121	0.74291964199426
GO:0050681	nuclear androgen receptor binding	5/2496	26/18639	0.192307692307692	1.43606693786982	0.263378096664121	0.74291964199426
GO:0070006	metalloaminopeptidase activity	5/2496	26/18639	0.192307692307692	1.43606693786982	0.263378096664121	0.74291964199426
GO:0004521	RNA endonuclease activity	12/2496	73/18639	0.164383561643836	1.22754214963119	0.26740915373726	0.752664557717375
GO:0005246	calcium channel regulator activity	9/2496	53/18639	0.169811320754717	1.26807420174165	0.274364163077946	0.763430834088729
GO:0001221	transcription coregulator binding	18/2496	115/18639	0.156521739130435	1.16883361204013	0.27466931073262	0.763430834088729
GO:0017124	SH3 domain binding	18/2496	115/18639	0.156521739130435	1.16883361204013	0.27466931073262	0.763430834088729
GO:0010851	cyclase regulator activity	4/2496	20/18639	0.2	1.49350961538462	0.275361354838001	0.763430834088729
GO:0030742	GTP-dependent protein binding	4/2496	20/18639	0.2	1.49350961538462	0.275361354838001	0.763430834088729
GO:0140939	histone H4 methyltransferase activity	4/2496	20/18639	0.2	1.49350961538462	0.275361354838001	0.763430834088729
GO:0019956	chemokine binding	6/2496	33/18639	0.181818181818182	1.35773601398601	0.275559339067329	0.763430834088729
GO:0004714	transmembrane receptor protein tyrosine kinase activity	10/2496	60/18639	0.166666666666667	1.24459134615385	0.27828601580239	0.763430834088729
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	11/2496	67/18639	0.164179104477612	1.22601535591274	0.281198182752242	0.763430834088729
GO:0004177	aminopeptidase activity	7/2496	40/18639	0.175	1.30682091346154	0.283732362360058	0.763430834088729
GO:0071949	FAD binding	7/2496	40/18639	0.175	1.30682091346154	0.283732362360058	0.763430834088729
GO:0033192	calmodulin-dependent protein phosphatase activity	13/2496	81/18639	0.160493827160494	1.19849537037037	0.284918000204955	0.763430834088729
GO:0140791	histone H2AXS140 phosphatase activity	13/2496	81/18639	0.160493827160494	1.19849537037037	0.284918000204955	0.763430834088729
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	13/2496	81/18639	0.160493827160494	1.19849537037037	0.284918000204955	0.763430834088729
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	13/2496	81/18639	0.160493827160494	1.19849537037037	0.284918000204955	0.763430834088729
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	13/2496	81/18639	0.160493827160494	1.19849537037037	0.284918000204955	0.763430834088729
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	13/2496	81/18639	0.160493827160494	1.19849537037037	0.284918000204955	0.763430834088729
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	13/2496	81/18639	0.160493827160494	1.19849537037037	0.284918000204955	0.763430834088729
GO:1990439	MAP kinase serine/threonine phosphatase activity	13/2496	81/18639	0.160493827160494	1.19849537037037	0.284918000204955	0.763430834088729
GO:0004065	arylsulfatase activity	3/2496	14/18639	0.214285714285714	1.60018887362637	0.286432701916905	0.763430834088729
GO:0005161	platelet-derived growth factor receptor binding	3/2496	14/18639	0.214285714285714	1.60018887362637	0.286432701916905	0.763430834088729
GO:0016530	metallochaperone activity	3/2496	14/18639	0.214285714285714	1.60018887362637	0.286432701916905	0.763430834088729
GO:0042813	Wnt receptor activity	3/2496	14/18639	0.214285714285714	1.60018887362637	0.286432701916905	0.763430834088729
GO:0044548	S100 protein binding	3/2496	14/18639	0.214285714285714	1.60018887362637	0.286432701916905	0.763430834088729
GO:0070742	C2H2 zinc finger domain binding	3/2496	14/18639	0.214285714285714	1.60018887362637	0.286432701916905	0.763430834088729
GO:1990825	sequence-specific mRNA binding	3/2496	14/18639	0.214285714285714	1.60018887362637	0.286432701916905	0.763430834088729
GO:0005385	zinc ion transmembrane transporter activity	5/2496	27/18639	0.185185185185185	1.38287927350427	0.290625871143304	0.769893281365427
GO:0023026	MHC class II protein complex binding	5/2496	27/18639	0.185185185185185	1.38287927350427	0.290625871143304	0.769893281365427
GO:0035255	ionotropic glutamate receptor binding	5/2496	27/18639	0.185185185185185	1.38287927350427	0.290625871143304	0.769893281365427
GO:0005262	calcium channel activity	20/2496	131/18639	0.152671755725191	1.14008367586612	0.299146836265325	0.786299007416744
GO:0008376	acetylgalactosaminyltransferase activity	6/2496	34/18639	0.176470588235294	1.31780260180995	0.300011299410411	0.786299007416744
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	6/2496	34/18639	0.176470588235294	1.31780260180995	0.300011299410411	0.786299007416744
GO:0030332	cyclin binding	6/2496	34/18639	0.176470588235294	1.31780260180995	0.300011299410411	0.786299007416744
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	13/2496	82/18639	0.158536585365854	1.18387957317073	0.300431244028297	0.786299007416744
GO:0033549	MAP kinase phosphatase activity	13/2496	82/18639	0.158536585365854	1.18387957317073	0.300431244028297	0.786299007416744
GO:0016407	acetyltransferase activity	15/2496	96/18639	0.15625	1.16680438701923	0.30109307602918	0.786455114588218
GO:0016757	glycosyltransferase activity	39/2496	267/18639	0.146067415730337	1.0907654494382	0.303999614870644	0.792462069902318
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	7/2496	41/18639	0.170731707317073	1.2749472326454	0.306086477514462	0.792887226876001
GO:0017080	sodium channel regulator activity	7/2496	41/18639	0.170731707317073	1.2749472326454	0.306086477514462	0.792887226876001
GO:0042169	SH2 domain binding	7/2496	41/18639	0.170731707317073	1.2749472326454	0.306086477514462	0.792887226876001
GO:0010314	phosphatidylinositol-5-phosphate binding	4/2496	21/18639	0.19047619047619	1.42239010989011	0.307198267074469	0.792887226876001
GO:0019200	carbohydrate kinase activity	4/2496	21/18639	0.19047619047619	1.42239010989011	0.307198267074469	0.792887226876001
GO:0016879	ligase activity, forming carbon-nitrogen bonds	8/2496	48/18639	0.166666666666667	1.24459134615385	0.31010802268984	0.798818693556078
GO:0017022	myosin binding	12/2496	76/18639	0.157894736842105	1.17908653846154	0.316034158479952	0.812481517666962
GO:0019789	SUMO transferase activity	5/2496	28/18639	0.178571428571429	1.33349072802198	0.318331365154252	0.813582706245506
GO:0045499	chemorepellent activity	5/2496	28/18639	0.178571428571429	1.33349072802198	0.318331365154252	0.813582706245506
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	5/2496	28/18639	0.178571428571429	1.33349072802198	0.318331365154252	0.813582706245506
GO:0004713	protein tyrosine kinase activity	21/2496	140/18639	0.15	1.12013221153846	0.322578275779269	0.822826617515089
GO:0005154	epidermal growth factor receptor binding	6/2496	35/18639	0.171428571428571	1.2801510989011	0.324842358157277	0.823520833441392
GO:0008242	omega peptidase activity	3/2496	15/18639	0.2	1.49350961538462	0.325372702952342	0.823520833441392
GO:0015929	hexosaminidase activity	3/2496	15/18639	0.2	1.49350961538462	0.325372702952342	0.823520833441392
GO:0120283	protein serine/threonine kinase binding	3/2496	15/18639	0.2	1.49350961538462	0.325372702952342	0.823520833441392
GO:0031492	nucleosomal DNA binding	7/2496	42/18639	0.166666666666667	1.24459134615385	0.328768179205756	0.828902011665478
GO:0035198	miRNA binding	7/2496	42/18639	0.166666666666667	1.24459134615385	0.328768179205756	0.828902011665478
GO:0016763	pentosyltransferase activity	8/2496	49/18639	0.163265306122449	1.21919152276295	0.331103297675802	0.830019202139776
GO:0035254	glutamate receptor binding	8/2496	49/18639	0.163265306122449	1.21919152276295	0.331103297675802	0.830019202139776
GO:0017018	myosin phosphatase activity	13/2496	84/18639	0.154761904761905	1.15569196428571	0.332111543521226	0.830019202139776
GO:0019212	phosphatase inhibitor activity	9/2496	56/18639	0.160714285714286	1.20014165521978	0.332393825753164	0.830019202139776
GO:0016782	transferase activity, transferring sulphur-containing groups	11/2496	70/18639	0.157142857142857	1.17347184065934	0.333024549709987	0.830019202139776
GO:0097110	scaffold protein binding	11/2496	70/18639	0.157142857142857	1.17347184065934	0.333024549709987	0.830019202139776
GO:0003713	transcription coactivator activity	37/2496	256/18639	0.14453125	1.07929405799279	0.334311920193232	0.831640700518783
GO:0015377	chloride:monoatomic cation symporter activity	4/2496	22/18639	0.181818181818182	1.35773601398601	0.339369770700682	0.839425985861914
GO:0016881	acid-amino acid ligase activity	4/2496	22/18639	0.181818181818182	1.35773601398601	0.339369770700682	0.839425985861914
GO:0031683	G-protein beta/gamma-subunit complex binding	4/2496	22/18639	0.181818181818182	1.35773601398601	0.339369770700682	0.839425985861914
GO:0005319	lipid transporter activity	26/2496	178/18639	0.146067415730337	1.0907654494382	0.348049107330532	0.859266794279158
GO:0044390	ubiquitin-like protein conjugating enzyme binding	6/2496	36/18639	0.166666666666667	1.24459134615385	0.349934576358819	0.862291616461543
GO:0019888	protein phosphatase regulator activity	16/2496	107/18639	0.149532710280374	1.1166427030913	0.358016213487262	0.880544585337785
GO:0005149	interleukin-1 receptor binding	3/2496	16/18639	0.1875	1.40016526442308	0.36428906129286	0.881039840830509
GO:0005521	lamin binding	3/2496	16/18639	0.1875	1.40016526442308	0.36428906129286	0.881039840830509
GO:0015923	mannosidase activity	3/2496	16/18639	0.1875	1.40016526442308	0.36428906129286	0.881039840830509
GO:0016722	oxidoreductase activity, acting on metal ions	3/2496	16/18639	0.1875	1.40016526442308	0.36428906129286	0.881039840830509
GO:0019841	retinol binding	3/2496	16/18639	0.1875	1.40016526442308	0.36428906129286	0.881039840830509
GO:0022858	alanine transmembrane transporter activity	3/2496	16/18639	0.1875	1.40016526442308	0.36428906129286	0.881039840830509
GO:0031435	mitogen-activated protein kinase kinase kinase binding	3/2496	16/18639	0.1875	1.40016526442308	0.36428906129286	0.881039840830509
GO:0034450	ubiquitin-ubiquitin ligase activity	3/2496	16/18639	0.1875	1.40016526442308	0.36428906129286	0.881039840830509
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	3/2496	16/18639	0.1875	1.40016526442308	0.36428906129286	0.881039840830509
GO:0160215	deacylase activity	10/2496	65/18639	0.153846153846154	1.14885355029586	0.370470718503416	0.882669883287103
GO:0016849	phosphorus-oxygen lyase activity	4/2496	23/18639	0.173913043478261	1.29870401337793	0.371634681128895	0.882669883287103
GO:0061980	regulatory RNA binding	9/2496	58/18639	0.155172413793103	1.1587574602122	0.372208682537627	0.882669883287103
GO:0005021	vascular endothelial growth factor receptor activity	8/2496	51/18639	0.156862745098039	1.17138009049774	0.373687717404391	0.882669883287103
GO:0048019	receptor antagonist activity	5/2496	30/18639	0.166666666666667	1.24459134615385	0.374457363218256	0.882669883287103
GO:0001046	core promoter sequence-specific DNA binding	7/2496	44/18639	0.159090909090909	1.18801901223776	0.374760405569692	0.882669883287103
GO:0030547	signaling receptor inhibitor activity	7/2496	44/18639	0.159090909090909	1.18801901223776	0.374760405569692	0.882669883287103
GO:0023023	MHC protein complex binding	6/2496	37/18639	0.162162162162162	1.21095374220374	0.375173642599839	0.882669883287103
GO:0015171	amino acid transmembrane transporter activity	15/2496	102/18639	0.147058823529412	1.09816883484163	0.390466307859831	0.882669883287103
GO:0031593	polyubiquitin modification-dependent protein binding	9/2496	59/18639	0.152542372881356	1.13911750325945	0.392285904677212	0.882669883287103
GO:0000182	rDNA binding	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0005131	growth hormone receptor binding	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0005345	purine nucleobase transmembrane transporter activity	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0005381	iron ion transmembrane transporter activity	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0008190	eukaryotic initiation factor 4E binding	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0008641	ubiquitin-like modifier activating enzyme activity	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0015658	branched-chain amino acid transmembrane transporter activity	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0016175	superoxide-generating NAD(P)H oxidase activity	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0016783	sulfurtransferase activity	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0016868	intramolecular phosphotransferase activity	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0019911	structural constituent of myelin sheath	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0031434	mitogen-activated protein kinase kinase binding	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0031957	very long-chain fatty acid-CoA ligase activity	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0031996	thioesterase binding	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0032052	bile acid binding	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0033204	ribonuclease P RNA binding	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0035256	G protein-coupled glutamate receptor binding	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0035374	chondroitin sulfate binding	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0043208	glycosphingolipid binding	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0043295	glutathione binding	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0043422	protein kinase B binding	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0045322	unmethylated CpG binding	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0050815	phosphoserine residue binding	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0051864	histone H3K36 demethylase activity	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0051880	G-quadruplex DNA binding	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0070513	death domain binding	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0070739	protein-glutamic acid ligase activity	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0070740	tubulin-glutamic acid ligase activity	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0098505	G-rich strand telomeric DNA binding	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0140135	mechanosensitive monoatomic cation channel activity	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:1905394	retromer complex binding	2/2496	10/18639	0.2	1.49350961538462	0.395368777781971	0.882669883287103
GO:0004715	non-membrane spanning protein tyrosine kinase activity	7/2496	45/18639	0.155555555555556	1.16161858974359	0.397899352948231	0.882669883287103
GO:0140303	intramembrane lipid transporter activity	7/2496	45/18639	0.155555555555556	1.16161858974359	0.397899352948231	0.882669883287103
GO:0004549	tRNA-specific ribonuclease activity	3/2496	17/18639	0.176470588235294	1.31780260180995	0.402811064654758	0.882669883287103
GO:0004659	prenyltransferase activity	3/2496	17/18639	0.176470588235294	1.31780260180995	0.402811064654758	0.882669883287103
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/2496	17/18639	0.176470588235294	1.31780260180995	0.402811064654758	0.882669883287103
GO:0008484	sulfuric ester hydrolase activity	3/2496	17/18639	0.176470588235294	1.31780260180995	0.402811064654758	0.882669883287103
GO:0016018	cyclosporin A binding	3/2496	17/18639	0.176470588235294	1.31780260180995	0.402811064654758	0.882669883287103
GO:0016805	dipeptidase activity	3/2496	17/18639	0.176470588235294	1.31780260180995	0.402811064654758	0.882669883287103
GO:0017110	nucleoside diphosphate phosphatase activity	3/2496	17/18639	0.176470588235294	1.31780260180995	0.402811064654758	0.882669883287103
GO:0019198	transmembrane receptor protein phosphatase activity	3/2496	17/18639	0.176470588235294	1.31780260180995	0.402811064654758	0.882669883287103
GO:0030548	acetylcholine receptor regulator activity	3/2496	17/18639	0.176470588235294	1.31780260180995	0.402811064654758	0.882669883287103
GO:0070402	NADPH binding	3/2496	17/18639	0.176470588235294	1.31780260180995	0.402811064654758	0.882669883287103
GO:0003684	damaged DNA binding	11/2496	74/18639	0.148648648648649	1.11004093035343	0.40452400528727	0.884938611231448
GO:0004864	protein phosphatase inhibitor activity	8/2496	53/18639	0.150943396226415	1.1271770682148	0.416611513734379	0.905315535669051
GO:0008146	sulfotransferase activity	8/2496	53/18639	0.150943396226415	1.1271770682148	0.416611513734379	0.905315535669051
GO:0038064	collagen receptor activity	8/2496	53/18639	0.150943396226415	1.1271770682148	0.416611513734379	0.905315535669051
GO:1901505	carbohydrate derivative transmembrane transporter activity	8/2496	53/18639	0.150943396226415	1.1271770682148	0.416611513734379	0.905315535669051
GO:0030276	clathrin binding	7/2496	46/18639	0.152173913043478	1.13636601170569	0.421024228685528	0.908588392862587
GO:0005516	calmodulin binding	29/2496	207/18639	0.140096618357488	1.04617823299889	0.427039874956662	0.908588392862587
GO:0008378	galactosyltransferase activity	5/2496	32/18639	0.15625	1.16680438701923	0.43052556750199	0.908588392862587
GO:0005200	structural constituent of cytoskeleton	16/2496	112/18639	0.142857142857143	1.06679258241758	0.431493692988752	0.908588392862587
GO:0015026	coreceptor activity	9/2496	61/18639	0.147540983606557	1.10176938839849	0.432508915430758	0.908588392862587
GO:0019905	syntaxin binding	9/2496	61/18639	0.147540983606557	1.10176938839849	0.432508915430758	0.908588392862587
GO:0004709	MAP kinase kinase kinase activity	4/2496	25/18639	0.16	1.19480769230769	0.435584266876227	0.908588392862587
GO:0005537	D-mannose binding	4/2496	25/18639	0.16	1.19480769230769	0.435584266876227	0.908588392862587
GO:0015296	monoatomic anion:monoatomic cation symporter activity	4/2496	25/18639	0.16	1.19480769230769	0.435584266876227	0.908588392862587
GO:0004706	JUN kinase kinase kinase activity	3/2496	18/18639	0.166666666666667	1.24459134615385	0.440624631646521	0.908588392862587
GO:0004970	glutamate-gated receptor activity	3/2496	18/18639	0.166666666666667	1.24459134615385	0.440624631646521	0.908588392862587
GO:0008409	5'-3' exonuclease activity	3/2496	18/18639	0.166666666666667	1.24459134615385	0.440624631646521	0.908588392862587
GO:0015172	acidic amino acid transmembrane transporter activity	3/2496	18/18639	0.166666666666667	1.24459134615385	0.440624631646521	0.908588392862587
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	3/2496	18/18639	0.166666666666667	1.24459134615385	0.440624631646521	0.908588392862587
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	3/2496	18/18639	0.166666666666667	1.24459134615385	0.440624631646521	0.908588392862587
GO:0017075	syntaxin-1 binding	3/2496	18/18639	0.166666666666667	1.24459134615385	0.440624631646521	0.908588392862587
GO:0034185	apolipoprotein binding	3/2496	18/18639	0.166666666666667	1.24459134615385	0.440624631646521	0.908588392862587
GO:0050811	GABA receptor binding	3/2496	18/18639	0.166666666666667	1.24459134615385	0.440624631646521	0.908588392862587
GO:0070064	proline-rich region binding	3/2496	18/18639	0.166666666666667	1.24459134615385	0.440624631646521	0.908588392862587
GO:0099602	neurotransmitter receptor regulator activity	3/2496	18/18639	0.166666666666667	1.24459134615385	0.440624631646521	0.908588392862587
GO:0043495	protein-membrane adaptor activity	7/2496	47/18639	0.148936170212766	1.11218801145663	0.444057813836091	0.908588392862587
GO:0001851	complement component C3b binding	2/2496	11/18639	0.181818181818182	1.35773601398601	0.444554351484834	0.908588392862587
GO:0003953	NAD+ nucleosidase activity	2/2496	11/18639	0.181818181818182	1.35773601398601	0.444554351484834	0.908588392862587
GO:0005114	type II transforming growth factor beta receptor binding	2/2496	11/18639	0.181818181818182	1.35773601398601	0.444554351484834	0.908588392862587
GO:0008172	S-methyltransferase activity	2/2496	11/18639	0.181818181818182	1.35773601398601	0.444554351484834	0.908588392862587
GO:0008199	ferric iron binding	2/2496	11/18639	0.181818181818182	1.35773601398601	0.444554351484834	0.908588392862587
GO:0008503	benzodiazepine receptor activity	2/2496	11/18639	0.181818181818182	1.35773601398601	0.444554351484834	0.908588392862587
GO:0015205	nucleobase transmembrane transporter activity	2/2496	11/18639	0.181818181818182	1.35773601398601	0.444554351484834	0.908588392862587
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	2/2496	11/18639	0.181818181818182	1.35773601398601	0.444554351484834	0.908588392862587
GO:0019107	myristoyltransferase activity	2/2496	11/18639	0.181818181818182	1.35773601398601	0.444554351484834	0.908588392862587
GO:0032050	clathrin heavy chain binding	2/2496	11/18639	0.181818181818182	1.35773601398601	0.444554351484834	0.908588392862587
GO:0035252	UDP-xylosyltransferase activity	2/2496	11/18639	0.181818181818182	1.35773601398601	0.444554351484834	0.908588392862587
GO:0042285	xylosyltransferase activity	2/2496	11/18639	0.181818181818182	1.35773601398601	0.444554351484834	0.908588392862587
GO:0045294	alpha-catenin binding	2/2496	11/18639	0.181818181818182	1.35773601398601	0.444554351484834	0.908588392862587
GO:0047676	arachidonate-CoA ligase activity	2/2496	11/18639	0.181818181818182	1.35773601398601	0.444554351484834	0.908588392862587
GO:0070697	activin receptor binding	2/2496	11/18639	0.181818181818182	1.35773601398601	0.444554351484834	0.908588392862587
GO:0140537	transcription regulator activator activity	2/2496	11/18639	0.181818181818182	1.35773601398601	0.444554351484834	0.908588392862587
GO:1900750	oligopeptide binding	2/2496	11/18639	0.181818181818182	1.35773601398601	0.444554351484834	0.908588392862587
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	13/2496	91/18639	0.142857142857143	1.06679258241758	0.446709289452584	0.911566143789179
GO:0008234	cysteine-type peptidase activity	26/2496	187/18639	0.13903743315508	1.03826871657754	0.450463512872516	0.916856615035528
GO:0071855	neuropeptide receptor binding	6/2496	40/18639	0.15	1.12013221153846	0.450705931740282	0.916856615035528
GO:0030296	protein tyrosine kinase activator activity	5/2496	33/18639	0.151515151515152	1.13144667832168	0.458198108293894	0.930648101760227
GO:0004435	phosphatidylinositol phospholipase C activity	4/2496	26/18639	0.153846153846154	1.14885355029586	0.466894479642065	0.940994121007
GO:0004529	DNA exonuclease activity	4/2496	26/18639	0.153846153846154	1.14885355029586	0.466894479642065	0.940994121007
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	4/2496	26/18639	0.153846153846154	1.14885355029586	0.466894479642065	0.940994121007
GO:0030247	polysaccharide binding	4/2496	26/18639	0.153846153846154	1.14885355029586	0.466894479642065	0.940994121007
GO:0030507	spectrin binding	4/2496	26/18639	0.153846153846154	1.14885355029586	0.466894479642065	0.940994121007
GO:0043130	ubiquitin binding	14/2496	100/18639	0.14	1.04545673076923	0.472973300175056	0.947682738232535
GO:0001530	lipopolysaccharide binding	6/2496	41/18639	0.146341463414634	1.09281191369606	0.475497838178994	0.947682738232535
GO:0140828	metal cation:monoatomic cation antiporter activity	6/2496	41/18639	0.146341463414634	1.09281191369606	0.475497838178994	0.947682738232535
GO:0035401	histone H3Y41 kinase activity	16/2496	115/18639	0.139130434782609	1.03896321070234	0.475764711748838	0.947682738232535
GO:0140801	histone H2AXY142 kinase activity	16/2496	115/18639	0.139130434782609	1.03896321070234	0.475764711748838	0.947682738232535
GO:0019199	transmembrane receptor protein kinase activity	11/2496	78/18639	0.141025641025641	1.05311575443787	0.476468956268653	0.947682738232535
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	3/2496	19/18639	0.157894736842105	1.17908653846154	0.4774695572412	0.947682738232535
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/2496	19/18639	0.157894736842105	1.17908653846154	0.4774695572412	0.947682738232535
GO:0031420	alkali metal ion binding	3/2496	19/18639	0.157894736842105	1.17908653846154	0.4774695572412	0.947682738232535
GO:0046527	glucosyltransferase activity	3/2496	19/18639	0.157894736842105	1.17908653846154	0.4774695572412	0.947682738232535
GO:0050660	flavin adenine dinucleotide binding	12/2496	86/18639	0.13953488372093	1.04198345259392	0.486603225413701	0.950796595353307
GO:0015291	secondary active transmembrane transporter activity	39/2496	287/18639	0.13588850174216	1.01475391986063	0.487064607741658	0.950796595353307
GO:0060590	ATPase regulator activity	7/2496	49/18639	0.142857142857143	1.06679258241758	0.489564622489498	0.950796595353307
GO:0003995	acyl-CoA dehydrogenase activity	2/2496	12/18639	0.166666666666667	1.24459134615385	0.491414779374795	0.950796595353307
GO:0004526	ribonuclease P activity	2/2496	12/18639	0.166666666666667	1.24459134615385	0.491414779374795	0.950796595353307
GO:0005078	MAP-kinase scaffold activity	2/2496	12/18639	0.166666666666667	1.24459134615385	0.491414779374795	0.950796595353307
GO:0008504	monoamine transmembrane transporter activity	2/2496	12/18639	0.166666666666667	1.24459134615385	0.491414779374795	0.950796595353307
GO:0015368	calcium:monoatomic cation antiporter activity	2/2496	12/18639	0.166666666666667	1.24459134615385	0.491414779374795	0.950796595353307
GO:0016208	AMP binding	2/2496	12/18639	0.166666666666667	1.24459134615385	0.491414779374795	0.950796595353307
GO:0035014	phosphatidylinositol 3-kinase regulator activity	2/2496	12/18639	0.166666666666667	1.24459134615385	0.491414779374795	0.950796595353307
GO:0035197	siRNA binding	2/2496	12/18639	0.166666666666667	1.24459134615385	0.491414779374795	0.950796595353307
GO:0035259	nuclear glucocorticoid receptor binding	2/2496	12/18639	0.166666666666667	1.24459134615385	0.491414779374795	0.950796595353307
GO:0035497	cAMP response element binding	2/2496	12/18639	0.166666666666667	1.24459134615385	0.491414779374795	0.950796595353307
GO:0043047	single-stranded telomeric DNA binding	2/2496	12/18639	0.166666666666667	1.24459134615385	0.491414779374795	0.950796595353307
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	2/2496	12/18639	0.166666666666667	1.24459134615385	0.491414779374795	0.950796595353307
GO:0097677	STAT family protein binding	2/2496	12/18639	0.166666666666667	1.24459134615385	0.491414779374795	0.950796595353307
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	2/2496	12/18639	0.166666666666667	1.24459134615385	0.491414779374795	0.950796595353307
GO:0004866	endopeptidase inhibitor activity	22/2496	161/18639	0.136645962732919	1.02041029622551	0.494365797859225	0.955091319532763
GO:0001671	ATPase activator activity	4/2496	27/18639	0.148148148148148	1.10630341880342	0.497549889815762	0.958407309881099
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	4/2496	27/18639	0.148148148148148	1.10630341880342	0.497549889815762	0.958407309881099
GO:0030414	peptidase inhibitor activity	23/2496	169/18639	0.136094674556213	1.01629352526172	0.5009660126153	0.963566439581121
GO:0005007	fibroblast growth factor receptor activity	7/2496	50/18639	0.14	1.04545673076923	0.511906842657603	0.974062846005889
GO:0015605	organophosphate ester transmembrane transporter activity	7/2496	50/18639	0.14	1.04545673076923	0.511906842657603	0.974062846005889
GO:0000339	RNA cap binding	3/2496	20/18639	0.15	1.12013221153846	0.513135710606471	0.974062846005889
GO:0001614	purinergic nucleotide receptor activity	3/2496	20/18639	0.15	1.12013221153846	0.513135710606471	0.974062846005889
GO:0005326	neurotransmitter transmembrane transporter activity	3/2496	20/18639	0.15	1.12013221153846	0.513135710606471	0.974062846005889
GO:0016004	phospholipase activator activity	3/2496	20/18639	0.15	1.12013221153846	0.513135710606471	0.974062846005889
GO:0016502	nucleotide receptor activity	3/2496	20/18639	0.15	1.12013221153846	0.513135710606471	0.974062846005889
GO:0043024	ribosomal small subunit binding	3/2496	20/18639	0.15	1.12013221153846	0.513135710606471	0.974062846005889
GO:0061608	nuclear import signal receptor activity	3/2496	20/18639	0.15	1.12013221153846	0.513135710606471	0.974062846005889
GO:0004712	protein serine/threonine/tyrosine kinase activity	6/2496	43/18639	0.13953488372093	1.04198345259392	0.52399563382042	0.993234104164686
GO:0005242	inward rectifier potassium channel activity	4/2496	28/18639	0.142857142857143	1.06679258241758	0.527419643926014	0.998275441981702
GO:0004465	lipoprotein lipase activity	2/2496	13/18639	0.153846153846154	1.14885355029586	0.535690641870512	0.99944568326127
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	2/2496	13/18639	0.153846153846154	1.14885355029586	0.535690641870512	0.99944568326127
GO:0005338	nucleotide-sugar transmembrane transporter activity	2/2496	13/18639	0.153846153846154	1.14885355029586	0.535690641870512	0.99944568326127
GO:0015651	quaternary ammonium group transmembrane transporter activity	2/2496	13/18639	0.153846153846154	1.14885355029586	0.535690641870512	0.99944568326127
GO:0039706	co-receptor binding	2/2496	13/18639	0.153846153846154	1.14885355029586	0.535690641870512	0.99944568326127
GO:0043560	insulin receptor substrate binding	2/2496	13/18639	0.153846153846154	1.14885355029586	0.535690641870512	0.99944568326127
GO:0046975	histone H3K36 methyltransferase activity	2/2496	13/18639	0.153846153846154	1.14885355029586	0.535690641870512	0.99944568326127
GO:0071714	icosanoid transmembrane transporter activity	2/2496	13/18639	0.153846153846154	1.14885355029586	0.535690641870512	0.99944568326127
GO:0089720	caspase binding	2/2496	13/18639	0.153846153846154	1.14885355029586	0.535690641870512	0.99944568326127
GO:0097157	pre-mRNA intronic binding	2/2496	13/18639	0.153846153846154	1.14885355029586	0.535690641870512	0.99944568326127
GO:0045505	dynein intermediate chain binding	5/2496	36/18639	0.138888888888889	1.03715945512821	0.538422071052392	1
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	3/2496	21/18639	0.142857142857143	1.06679258241758	0.547458617861805	1
GO:0009931	calcium-dependent protein serine/threonine kinase activity	3/2496	21/18639	0.142857142857143	1.06679258241758	0.547458617861805	1
GO:0015174	basic amino acid transmembrane transporter activity	3/2496	21/18639	0.142857142857143	1.06679258241758	0.547458617861805	1
GO:0070182	DNA polymerase binding	3/2496	21/18639	0.142857142857143	1.06679258241758	0.547458617861805	1
GO:0043014	alpha-tubulin binding	6/2496	44/18639	0.136363636363636	1.01830201048951	0.547559090912641	1
GO:0035250	UDP-galactosyltransferase activity	4/2496	29/18639	0.137931034482759	1.03000663129973	0.55639428443343	1
GO:0022829	wide pore channel activity	5/2496	37/18639	0.135135135135135	1.00912811850312	0.563929637998103	1
GO:0016922	nuclear receptor binding	18/2496	137/18639	0.131386861313869	0.981137703537339	0.572833416566244	1
GO:0005003	ephrin receptor activity	7/2496	53/18639	0.132075471698113	0.986279934687953	0.576612761021908	1
GO:0005005	transmembrane-ephrin receptor activity	7/2496	53/18639	0.132075471698113	0.986279934687953	0.576612761021908	1
GO:0051018	protein kinase A binding	7/2496	53/18639	0.132075471698113	0.986279934687953	0.576612761021908	1
GO:0004705	JUN kinase activity	2/2496	14/18639	0.142857142857143	1.06679258241758	0.57723363186278	1
GO:0005313	L-glutamate transmembrane transporter activity	2/2496	14/18639	0.142857142857143	1.06679258241758	0.57723363186278	1
GO:0005344	oxygen carrier activity	2/2496	14/18639	0.142857142857143	1.06679258241758	0.57723363186278	1
GO:0005545	1-phosphatidylinositol binding	2/2496	14/18639	0.142857142857143	1.06679258241758	0.57723363186278	1
GO:0008195	phosphatidate phosphatase activity	2/2496	14/18639	0.142857142857143	1.06679258241758	0.57723363186278	1
GO:0008494	translation activator activity	2/2496	14/18639	0.142857142857143	1.06679258241758	0.57723363186278	1
GO:0015386	potassium:proton antiporter activity	2/2496	14/18639	0.142857142857143	1.06679258241758	0.57723363186278	1
GO:0030983	mismatched DNA binding	2/2496	14/18639	0.142857142857143	1.06679258241758	0.57723363186278	1
GO:0042043	neurexin family protein binding	2/2496	14/18639	0.142857142857143	1.06679258241758	0.57723363186278	1
GO:0046030	inositol trisphosphate phosphatase activity	2/2496	14/18639	0.142857142857143	1.06679258241758	0.57723363186278	1
GO:0071933	Arp2/3 complex binding	2/2496	14/18639	0.142857142857143	1.06679258241758	0.57723363186278	1
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	2/2496	14/18639	0.142857142857143	1.06679258241758	0.57723363186278	1
GO:0098847	sequence-specific single stranded DNA binding	2/2496	14/18639	0.142857142857143	1.06679258241758	0.57723363186278	1
GO:1901612	cardiolipin binding	2/2496	14/18639	0.142857142857143	1.06679258241758	0.57723363186278	1
GO:0070034	telomerase RNA binding	3/2496	22/18639	0.136363636363636	1.01830201048951	0.580314751624087	1
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	30/2496	229/18639	0.131004366812227	0.978281407457172	0.581340506369164	1
GO:0003774	cytoskeletal motor activity	20/2496	153/18639	0.130718954248366	0.976150075414781	0.582443832630438	1
GO:0031624	ubiquitin conjugating enzyme binding	4/2496	30/18639	0.133333333333333	0.995673076923077	0.584384580004995	1
GO:0098918	structural constituent of synapse	4/2496	30/18639	0.133333333333333	0.995673076923077	0.584384580004995	1
GO:0042887	amide transmembrane transporter activity	5/2496	38/18639	0.131578947368421	0.982572115384615	0.58869927698985	1
GO:0004180	carboxypeptidase activity	6/2496	46/18639	0.130434782608696	0.974028010033445	0.593017581578873	1
GO:0008514	organic anion transmembrane transporter activity	35/2496	269/18639	0.130111524163569	0.971614062053188	0.600460947443143	1
GO:0015179	L-amino acid transmembrane transporter activity	8/2496	62/18639	0.129032258064516	0.96355459057072	0.601368843845208	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	9/2496	70/18639	0.128571428571429	0.960113324175824	0.605360322431899	1
GO:0004620	phospholipase activity	14/2496	109/18639	0.128440366972477	0.959134615384615	0.609372445758312	1
GO:0140457	protein demethylase activity	4/2496	31/18639	0.129032258064516	0.96355459057072	0.611320148441231	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	3/2496	23/18639	0.130434782608696	0.974028010033445	0.611616762198366	1
GO:0005283	amino acid:sodium symporter activity	3/2496	23/18639	0.130434782608696	0.974028010033445	0.611616762198366	1
GO:0070577	lysine-acetylated histone binding	3/2496	23/18639	0.130434782608696	0.974028010033445	0.611616762198366	1
GO:0099186	structural constituent of postsynapse	3/2496	23/18639	0.130434782608696	0.974028010033445	0.611616762198366	1
GO:0140359	ABC-type transporter activity	6/2496	47/18639	0.127659574468085	0.953304009819967	0.614816571980255	1
GO:0000774	adenyl-nucleotide exchange factor activity	2/2496	15/18639	0.133333333333333	0.995673076923077	0.61598146707977	1
GO:0004089	carbonate dehydratase activity	2/2496	15/18639	0.133333333333333	0.995673076923077	0.61598146707977	1
GO:0004467	long-chain fatty acid-CoA ligase activity	2/2496	15/18639	0.133333333333333	0.995673076923077	0.61598146707977	1
GO:0004559	alpha-mannosidase activity	2/2496	15/18639	0.133333333333333	0.995673076923077	0.61598146707977	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/2496	15/18639	0.133333333333333	0.995673076923077	0.61598146707977	1
GO:0004953	icosanoid receptor activity	2/2496	15/18639	0.133333333333333	0.995673076923077	0.61598146707977	1
GO:0015556	C4-dicarboxylate transmembrane transporter activity	2/2496	15/18639	0.133333333333333	0.995673076923077	0.61598146707977	1
GO:0045504	dynein heavy chain binding	2/2496	15/18639	0.133333333333333	0.995673076923077	0.61598146707977	1
GO:0050780	dopamine receptor binding	2/2496	15/18639	0.133333333333333	0.995673076923077	0.61598146707977	1
GO:0042562	hormone binding	12/2496	94/18639	0.127659574468085	0.953304009819967	0.616601807420565	1
GO:0004222	metalloendopeptidase activity	14/2496	110/18639	0.127272727272727	0.95041520979021	0.623545916109434	1
GO:0046332	SMAD binding	10/2496	79/18639	0.126582278481013	0.945259250243428	0.625889519833031	1
GO:0004867	serine-type endopeptidase inhibitor activity	12/2496	95/18639	0.126315789473684	0.943269230769231	0.631723439462936	1
GO:0032266	phosphatidylinositol-3-phosphate binding	6/2496	48/18639	0.125	0.933443509615385	0.635943612209826	1
GO:0004536	DNA nuclease activity	8/2496	64/18639	0.125	0.933443509615385	0.638381707288337	1
GO:0001091	RNA polymerase II general transcription initiation factor binding	3/2496	24/18639	0.125	0.933443509615385	0.641308817366602	1
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	3/2496	24/18639	0.125	0.933443509615385	0.641308817366602	1
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	3/2496	24/18639	0.125	0.933443509615385	0.641308817366602	1
GO:0004622	lysophospholipase activity	3/2496	24/18639	0.125	0.933443509615385	0.641308817366602	1
GO:0004806	triacylglycerol lipase activity	3/2496	24/18639	0.125	0.933443509615385	0.641308817366602	1
GO:0005315	phosphate transmembrane transporter activity	3/2496	24/18639	0.125	0.933443509615385	0.641308817366602	1
GO:0015295	solute:proton symporter activity	3/2496	24/18639	0.125	0.933443509615385	0.641308817366602	1
GO:0019957	C-C chemokine binding	3/2496	24/18639	0.125	0.933443509615385	0.641308817366602	1
GO:0030215	semaphorin receptor binding	3/2496	24/18639	0.125	0.933443509615385	0.641308817366602	1
GO:0030552	cAMP binding	3/2496	24/18639	0.125	0.933443509615385	0.641308817366602	1
GO:0060229	lipase activator activity	3/2496	24/18639	0.125	0.933443509615385	0.641308817366602	1
GO:0140033	acetylation-dependent protein binding	3/2496	24/18639	0.125	0.933443509615385	0.641308817366602	1
GO:0004519	endonuclease activity	16/2496	127/18639	0.125984251968504	0.940793458509994	0.643058840543405	1
GO:0042826	histone deacetylase binding	16/2496	127/18639	0.125984251968504	0.940793458509994	0.643058840543405	1
GO:0004175	endopeptidase activity	52/2496	405/18639	0.128395061728395	0.958796296296296	0.651291032473548	1
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	2/2496	16/18639	0.125	0.933443509615385	0.651937525049329	1
GO:0004707	MAP kinase activity	2/2496	16/18639	0.125	0.933443509615385	0.651937525049329	1
GO:0004708	MAP kinase kinase activity	2/2496	16/18639	0.125	0.933443509615385	0.651937525049329	1
GO:0005159	insulin-like growth factor receptor binding	2/2496	16/18639	0.125	0.933443509615385	0.651937525049329	1
GO:0005324	long-chain fatty acid transmembrane transporter activity	2/2496	16/18639	0.125	0.933443509615385	0.651937525049329	1
GO:0030275	LRR domain binding	2/2496	16/18639	0.125	0.933443509615385	0.651937525049329	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	2/2496	16/18639	0.125	0.933443509615385	0.651937525049329	1
GO:0070411	I-SMAD binding	2/2496	16/18639	0.125	0.933443509615385	0.651937525049329	1
GO:0097027	ubiquitin-protein transferase activator activity	2/2496	16/18639	0.125	0.933443509615385	0.651937525049329	1
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	2/2496	16/18639	0.125	0.933443509615385	0.651937525049329	1
GO:0019902	phosphatase binding	24/2496	190/18639	0.126315789473684	0.943269230769231	0.653391735050461	1
GO:0032182	ubiquitin-like protein binding	15/2496	120/18639	0.125	0.933443509615385	0.653445068861524	1
GO:0015932	nucleobase-containing compound transmembrane transporter activity	7/2496	57/18639	0.12280701754386	0.917067307692308	0.655870370427336	1
GO:0005004	GPI-linked ephrin receptor activity	6/2496	49/18639	0.122448979591837	0.914393642072214	0.65636858751964	1
GO:0005008	hepatocyte growth factor receptor activity	6/2496	49/18639	0.122448979591837	0.914393642072214	0.65636858751964	1
GO:0005009	insulin receptor activity	6/2496	49/18639	0.122448979591837	0.914393642072214	0.65636858751964	1
GO:0005011	macrophage colony-stimulating factor receptor activity	6/2496	49/18639	0.122448979591837	0.914393642072214	0.65636858751964	1
GO:0005018	platelet-derived growth factor alpha-receptor activity	6/2496	49/18639	0.122448979591837	0.914393642072214	0.65636858751964	1
GO:0005020	stem cell factor receptor activity	6/2496	49/18639	0.122448979591837	0.914393642072214	0.65636858751964	1
GO:0008288	boss receptor activity	6/2496	49/18639	0.122448979591837	0.914393642072214	0.65636858751964	1
GO:0036332	placental growth factor receptor activity	6/2496	49/18639	0.122448979591837	0.914393642072214	0.65636858751964	1
GO:0038062	protein tyrosine kinase collagen receptor activity	6/2496	49/18639	0.122448979591837	0.914393642072214	0.65636858751964	1
GO:0060175	brain-derived neurotrophic factor receptor activity	6/2496	49/18639	0.122448979591837	0.914393642072214	0.65636858751964	1
GO:0015101	organic cation transmembrane transporter activity	10/2496	81/18639	0.123456790123457	0.921919515669516	0.658069339055933	1
GO:0015175	neutral L-amino acid transmembrane transporter activity	5/2496	41/18639	0.121951219512195	0.910676594746717	0.658080348388033	1
GO:0003727	single-stranded RNA binding	11/2496	89/18639	0.123595505617978	0.922955380293863	0.65945674855222	1
GO:0019903	protein phosphatase binding	18/2496	144/18639	0.125	0.933443509615385	0.660414506452477	1
GO:0003697	single-stranded DNA binding	15/2496	121/18639	0.12396694214876	0.92572910044501	0.666349430760504	1
GO:0015108	chloride transmembrane transporter activity	15/2496	121/18639	0.12396694214876	0.92572910044501	0.666349430760504	1
GO:0035591	signaling adaptor activity	16/2496	129/18639	0.124031007751938	0.926207513416816	0.668247685453805	1
GO:0000030	mannosyltransferase activity	3/2496	25/18639	0.12	0.896105769230769	0.669362165160743	1
GO:0008139	nuclear localization sequence binding	3/2496	25/18639	0.12	0.896105769230769	0.669362165160743	1
GO:0008483	transaminase activity	3/2496	25/18639	0.12	0.896105769230769	0.669362165160743	1
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	3/2496	25/18639	0.12	0.896105769230769	0.669362165160743	1
GO:0017025	TBP-class protein binding	3/2496	25/18639	0.12	0.896105769230769	0.669362165160743	1
GO:0031491	nucleosome binding	9/2496	74/18639	0.121621621621622	0.908215306652807	0.673226218784765	1
GO:0008235	metalloexopeptidase activity	8/2496	66/18639	0.121212121212121	0.905157342657343	0.67338274495997	1
GO:0005006	epidermal growth factor receptor activity	6/2496	50/18639	0.12	0.896105769230769	0.676067916364463	1
GO:0005017	platelet-derived growth factor receptor activity	6/2496	50/18639	0.12	0.896105769230769	0.676067916364463	1
GO:0005019	platelet-derived growth factor beta-receptor activity	6/2496	50/18639	0.12	0.896105769230769	0.676067916364463	1
GO:0048020	CCR chemokine receptor binding	6/2496	50/18639	0.12	0.896105769230769	0.676067916364463	1
GO:0004497	monooxygenase activity	13/2496	106/18639	0.122641509433962	0.915831367924528	0.676307000414446	1
GO:0008569	minus-end-directed microtubule motor activity	2/2496	17/18639	0.117647058823529	0.878535067873303	0.685154386435272	1
GO:0031489	myosin V binding	2/2496	17/18639	0.117647058823529	0.878535067873303	0.685154386435272	1
GO:0038191	neuropilin binding	2/2496	17/18639	0.117647058823529	0.878535067873303	0.685154386435272	1
GO:0046965	nuclear retinoid X receptor binding	2/2496	17/18639	0.117647058823529	0.878535067873303	0.685154386435272	1
GO:0070403	NAD+ binding	2/2496	17/18639	0.117647058823529	0.878535067873303	0.685154386435272	1
GO:0070492	oligosaccharide binding	2/2496	17/18639	0.117647058823529	0.878535067873303	0.685154386435272	1
GO:0015020	glucuronosyltransferase activity	4/2496	34/18639	0.117647058823529	0.878535067873303	0.685345213365703	1
GO:0051427	hormone receptor binding	4/2496	34/18639	0.117647058823529	0.878535067873303	0.685345213365703	1
GO:0030165	PDZ domain binding	10/2496	83/18639	0.120481927710843	0.899704587581094	0.688617404435663	1
GO:0015459	potassium channel regulator activity	7/2496	59/18639	0.11864406779661	0.885980280312907	0.691953329757065	1
GO:0070063	RNA polymerase binding	7/2496	59/18639	0.11864406779661	0.885980280312907	0.691953329757065	1
GO:0070888	E-box binding	7/2496	59/18639	0.11864406779661	0.885980280312907	0.691953329757065	1
GO:0005010	insulin-like growth factor receptor activity	6/2496	51/18639	0.117647058823529	0.878535067873303	0.695024138686673	1
GO:0005030	neurotrophin receptor activity	6/2496	51/18639	0.117647058823529	0.878535067873303	0.695024138686673	1
GO:0004112	cyclic-nucleotide phosphodiesterase activity	3/2496	26/18639	0.115384615384615	0.861640162721893	0.695770993706658	1
GO:0008066	glutamate receptor activity	3/2496	26/18639	0.115384615384615	0.861640162721893	0.695770993706658	1
GO:0008157	protein phosphatase 1 binding	3/2496	26/18639	0.115384615384615	0.861640162721893	0.695770993706658	1
GO:0043548	phosphatidylinositol 3-kinase binding	3/2496	26/18639	0.115384615384615	0.861640162721893	0.695770993706658	1
GO:0052742	phosphatidylinositol kinase activity	3/2496	26/18639	0.115384615384615	0.861640162721893	0.695770993706658	1
GO:0046873	metal ion transmembrane transporter activity	57/2496	450/18639	0.126666666666667	0.945889423076923	0.696741652207069	1
GO:0008375	acetylglucosaminyltransferase activity	5/2496	43/18639	0.116279069767442	0.868319543828265	0.69990332072806	1
GO:0004527	exonuclease activity	10/2496	84/18639	0.119047619047619	0.888993818681319	0.703249394554011	1
GO:0140566	histone reader activity	4/2496	35/18639	0.114285714285714	0.853434065934066	0.707680950271607	1
GO:0046943	carboxylic acid transmembrane transporter activity	23/2496	188/18639	0.122340425531915	0.913583009410802	0.711681027879288	1
GO:0008525	phosphatidylcholine transporter activity	2/2496	18/18639	0.111111111111111	0.829727564102564	0.715720605783865	1
GO:0008509	monoatomic anion transmembrane transporter activity	18/2496	149/18639	0.120805369127517	0.90211990191017	0.716717608198582	1
GO:0004683	calcium/calmodulin-dependent protein kinase activity	3/2496	27/18639	0.111111111111111	0.829727564102564	0.72054863169302	1
GO:0005104	fibroblast growth factor receptor binding	3/2496	27/18639	0.111111111111111	0.829727564102564	0.72054863169302	1
GO:0008266	poly(U) RNA binding	3/2496	27/18639	0.111111111111111	0.829727564102564	0.72054863169302	1
GO:0005342	organic acid transmembrane transporter activity	23/2496	189/18639	0.121693121693122	0.908749236874237	0.72121173061878	1
GO:0002039	p53 binding	8/2496	69/18639	0.115942028985507	0.865802675585284	0.721827745360881	1
GO:0004190	aspartic-type endopeptidase activity	4/2496	36/18639	0.111111111111111	0.829727564102564	0.728838310174009	1
GO:0016409	palmitoyltransferase activity	4/2496	36/18639	0.111111111111111	0.829727564102564	0.728838310174009	1
GO:0140296	general transcription initiation factor binding	6/2496	53/18639	0.113207547169811	0.845382801161103	0.730665401738915	1
GO:0005085	guanyl-nucleotide exchange factor activity	28/2496	230/18639	0.121739130434783	0.909092809364549	0.73534343846548	1
GO:0005253	monoatomic anion channel activity	12/2496	103/18639	0.116504854368932	0.870005601194922	0.740577151152174	1
GO:0016866	intramolecular transferase activity	3/2496	28/18639	0.107142857142857	0.800094436813187	0.743724110225061	1
GO:0051959	dynein light intermediate chain binding	3/2496	28/18639	0.107142857142857	0.800094436813187	0.743724110225061	1
GO:0141052	histone H3 demethylase activity	3/2496	28/18639	0.107142857142857	0.800094436813187	0.743724110225061	1
GO:0005229	intracellularly calcium-gated chloride channel activity	2/2496	19/18639	0.105263157894737	0.786057692307692	0.743750140906532	1
GO:0008574	plus-end-directed microtubule motor activity	2/2496	19/18639	0.105263157894737	0.786057692307692	0.743750140906532	1
GO:0015245	fatty acid transmembrane transporter activity	2/2496	19/18639	0.105263157894737	0.786057692307692	0.743750140906532	1
GO:0016918	retinal binding	2/2496	19/18639	0.105263157894737	0.786057692307692	0.743750140906532	1
GO:0022821	solute:potassium antiporter activity	2/2496	19/18639	0.105263157894737	0.786057692307692	0.743750140906532	1
GO:0042577	lipid phosphatase activity	2/2496	19/18639	0.105263157894737	0.786057692307692	0.743750140906532	1
GO:0046624	sphingolipid transporter activity	2/2496	19/18639	0.105263157894737	0.786057692307692	0.743750140906532	1
GO:0141147	intracellularly calcium-gated channel activity	2/2496	19/18639	0.105263157894737	0.786057692307692	0.743750140906532	1
GO:0030551	cyclic nucleotide binding	4/2496	37/18639	0.108108108108108	0.807302494802495	0.748827240134725	1
GO:0070001	aspartic-type peptidase activity	4/2496	37/18639	0.108108108108108	0.807302494802495	0.748827240134725	1
GO:0140299	molecular sensor activity	8/2496	71/18639	0.112676056338028	0.841413867822319	0.751316349208876	1
GO:0060589	nucleoside-triphosphatase regulator activity	61/2496	490/18639	0.124489795918367	0.92963353610675	0.751638246024892	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	5/2496	46/18639	0.108695652173913	0.811690008361204	0.755726786128414	1
GO:0004540	RNA nuclease activity	14/2496	121/18639	0.115702479338843	0.864013827082009	0.760638094050764	1
GO:0140104	molecular carrier activity	30/2496	249/18639	0.120481927710843	0.899704587581094	0.760951010842873	1
GO:0001094	TFIID-class transcription factor complex binding	1/2496	10/18639	0.1	0.746754807692308	0.762614490211085	1
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	1/2496	10/18639	0.1	0.746754807692308	0.762614490211085	1
GO:0004382	GDP phosphatase activity	1/2496	10/18639	0.1	0.746754807692308	0.762614490211085	1
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	1/2496	10/18639	0.1	0.746754807692308	0.762614490211085	1
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/2496	10/18639	0.1	0.746754807692308	0.762614490211085	1
GO:0004955	prostaglandin receptor activity	1/2496	10/18639	0.1	0.746754807692308	0.762614490211085	1
GO:0008140	cAMP response element binding protein binding	1/2496	10/18639	0.1	0.746754807692308	0.762614490211085	1
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	1/2496	10/18639	0.1	0.746754807692308	0.762614490211085	1
GO:0008519	ammonium channel activity	1/2496	10/18639	0.1	0.746754807692308	0.762614490211085	1
GO:0015279	store-operated calcium channel activity	1/2496	10/18639	0.1	0.746754807692308	0.762614490211085	1
GO:0015643	toxic substance binding	1/2496	10/18639	0.1	0.746754807692308	0.762614490211085	1
GO:0015924	mannosyl-oligosaccharide mannosidase activity	1/2496	10/18639	0.1	0.746754807692308	0.762614490211085	1
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/2496	10/18639	0.1	0.746754807692308	0.762614490211085	1
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1/2496	10/18639	0.1	0.746754807692308	0.762614490211085	1
GO:0031419	cobalamin binding	1/2496	10/18639	0.1	0.746754807692308	0.762614490211085	1
GO:0031720	haptoglobin binding	1/2496	10/18639	0.1	0.746754807692308	0.762614490211085	1
GO:0032356	oxidized DNA binding	1/2496	10/18639	0.1	0.746754807692308	0.762614490211085	1
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	1/2496	10/18639	0.1	0.746754807692308	0.762614490211085	1
GO:0042975	peroxisome proliferator activated receptor binding	1/2496	10/18639	0.1	0.746754807692308	0.762614490211085	1
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/2496	10/18639	0.1	0.746754807692308	0.762614490211085	1
GO:0071723	lipopeptide binding	1/2496	10/18639	0.1	0.746754807692308	0.762614490211085	1
GO:0140940	histone H2A methyltransferase activity	1/2496	10/18639	0.1	0.746754807692308	0.762614490211085	1
GO:0140999	histone H3K4 trimethyltransferase activity	1/2496	10/18639	0.1	0.746754807692308	0.762614490211085	1
GO:1990259	histone H2AQ104 methyltransferase activity	1/2496	10/18639	0.1	0.746754807692308	0.762614490211085	1
GO:1990757	ubiquitin ligase activator activity	1/2496	10/18639	0.1	0.746754807692308	0.762614490211085	1
GO:0005416	amino acid:monoatomic cation symporter activity	3/2496	29/18639	0.103448275862069	0.772504973474801	0.765339090124095	1
GO:0016417	S-acyltransferase activity	3/2496	29/18639	0.103448275862069	0.772504973474801	0.765339090124095	1
GO:0106222	lncRNA binding	3/2496	29/18639	0.103448275862069	0.772504973474801	0.765339090124095	1
GO:0000146	microfilament motor activity	4/2496	38/18639	0.105263157894737	0.786057692307692	0.767665824034122	1
GO:0005501	retinoid binding	4/2496	38/18639	0.105263157894737	0.786057692307692	0.767665824034122	1
GO:0019840	isoprenoid binding	4/2496	38/18639	0.105263157894737	0.786057692307692	0.767665824034122	1
GO:0001972	retinoic acid binding	2/2496	20/18639	0.1	0.746754807692308	0.769373966495427	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	2/2496	20/18639	0.1	0.746754807692308	0.769373966495427	1
GO:0015095	magnesium ion transmembrane transporter activity	2/2496	20/18639	0.1	0.746754807692308	0.769373966495427	1
GO:0052745	inositol phosphate phosphatase activity	2/2496	20/18639	0.1	0.746754807692308	0.769373966495427	1
GO:0016298	lipase activity	15/2496	130/18639	0.115384615384615	0.861640162721893	0.769745660732871	1
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	15/2496	130/18639	0.115384615384615	0.861640162721893	0.769745660732871	1
GO:0016887	ATP hydrolysis activity	51/2496	417/18639	0.122302158273381	0.91329724681793	0.779385255692812	1
GO:0140375	immune receptor activity	18/2496	156/18639	0.115384615384615	0.861640162721893	0.785323551604309	1
GO:0000217	DNA secondary structure binding	4/2496	39/18639	0.102564102564103	0.765902366863905	0.78537898603823	1
GO:0008187	poly-pyrimidine tract binding	3/2496	30/18639	0.1	0.746754807692308	0.785445146803995	1
GO:0032452	histone demethylase activity	3/2496	30/18639	0.1	0.746754807692308	0.785445146803995	1
GO:0030695	GTPase regulator activity	60/2496	489/18639	0.122699386503067	0.916263567720623	0.788059611225125	1
GO:0140693	molecular condensate scaffold activity	5/2496	48/18639	0.104166666666667	0.777869591346154	0.788380672019035	1
GO:0005248	voltage-gated sodium channel activity	2/2496	21/18639	0.0952380952380952	0.711195054945055	0.792733476877914	1
GO:0008373	sialyltransferase activity	2/2496	21/18639	0.0952380952380952	0.711195054945055	0.792733476877914	1
GO:0009975	cyclase activity	2/2496	21/18639	0.0952380952380952	0.711195054945055	0.792733476877914	1
GO:0015125	bile acid transmembrane transporter activity	2/2496	21/18639	0.0952380952380952	0.711195054945055	0.792733476877914	1
GO:0035613	RNA stem-loop binding	2/2496	21/18639	0.0952380952380952	0.711195054945055	0.792733476877914	1
GO:0036122	BMP binding	2/2496	21/18639	0.0952380952380952	0.711195054945055	0.792733476877914	1
GO:0051428	peptide hormone receptor binding	2/2496	21/18639	0.0952380952380952	0.711195054945055	0.792733476877914	1
GO:0061891	calcium ion sensor activity	2/2496	21/18639	0.0952380952380952	0.711195054945055	0.792733476877914	1
GO:0015103	inorganic anion transmembrane transporter activity	19/2496	165/18639	0.115151515151515	0.859899475524476	0.793032624761127	1
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	1/2496	11/18639	0.0909090909090909	0.678868006993007	0.79442050408371	1
GO:0000099	sulfur amino acid transmembrane transporter activity	1/2496	11/18639	0.0909090909090909	0.678868006993007	0.79442050408371	1
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	1/2496	11/18639	0.0909090909090909	0.678868006993007	0.79442050408371	1
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	1/2496	11/18639	0.0909090909090909	0.678868006993007	0.79442050408371	1
GO:0004016	adenylate cyclase activity	1/2496	11/18639	0.0909090909090909	0.678868006993007	0.79442050408371	1
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/2496	11/18639	0.0909090909090909	0.678868006993007	0.79442050408371	1
GO:0004523	RNA-DNA hybrid ribonuclease activity	1/2496	11/18639	0.0909090909090909	0.678868006993007	0.79442050408371	1
GO:0004954	prostanoid receptor activity	1/2496	11/18639	0.0909090909090909	0.678868006993007	0.79442050408371	1
GO:0008271	secondary active sulfate transmembrane transporter activity	1/2496	11/18639	0.0909090909090909	0.678868006993007	0.79442050408371	1
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	1/2496	11/18639	0.0909090909090909	0.678868006993007	0.79442050408371	1
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/2496	11/18639	0.0909090909090909	0.678868006993007	0.79442050408371	1
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/2496	11/18639	0.0909090909090909	0.678868006993007	0.79442050408371	1
GO:0019215	intermediate filament binding	1/2496	11/18639	0.0909090909090909	0.678868006993007	0.79442050408371	1
GO:0032404	mismatch repair complex binding	1/2496	11/18639	0.0909090909090909	0.678868006993007	0.79442050408371	1
GO:0034056	estrogen response element binding	1/2496	11/18639	0.0909090909090909	0.678868006993007	0.79442050408371	1
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/2496	11/18639	0.0909090909090909	0.678868006993007	0.79442050408371	1
GO:0048185	activin binding	1/2496	11/18639	0.0909090909090909	0.678868006993007	0.79442050408371	1
GO:0050998	nitric-oxide synthase binding	1/2496	11/18639	0.0909090909090909	0.678868006993007	0.79442050408371	1
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/2496	11/18639	0.0909090909090909	0.678868006993007	0.79442050408371	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/2496	11/18639	0.0909090909090909	0.678868006993007	0.79442050408371	1
GO:0005254	chloride channel activity	9/2496	83/18639	0.108433734939759	0.809734128822984	0.797789583219763	1
GO:0030331	nuclear estrogen receptor binding	4/2496	40/18639	0.1	0.746754807692308	0.801997296863984	1
GO:0003725	double-stranded RNA binding	8/2496	75/18639	0.106666666666667	0.796538461538462	0.803509376137337	1
GO:0005184	neuropeptide hormone activity	3/2496	31/18639	0.0967741935483871	0.72266594292804	0.804101396628577	1
GO:0008327	methyl-CpG binding	3/2496	31/18639	0.0967741935483871	0.72266594292804	0.804101396628577	1
GO:0047499	calcium-independent phospholipase A2 activity	3/2496	31/18639	0.0967741935483871	0.72266594292804	0.804101396628577	1
GO:0072349	modified amino acid transmembrane transporter activity	3/2496	31/18639	0.0967741935483871	0.72266594292804	0.804101396628577	1
GO:0052689	carboxylic ester hydrolase activity	10/2496	92/18639	0.108695652173913	0.811690008361204	0.804169551439347	1
GO:0016500	protein-hormone receptor activity	7/2496	67/18639	0.104477611940299	0.780191590126292	0.810598666292106	1
GO:0008093	cytoskeletal anchor activity	2/2496	22/18639	0.0909090909090909	0.678868006993007	0.813975349403297	1
GO:0008970	phospholipase A1 activity	2/2496	22/18639	0.0909090909090909	0.678868006993007	0.813975349403297	1
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	2/2496	22/18639	0.0909090909090909	0.678868006993007	0.813975349403297	1
GO:0033691	sialic acid binding	2/2496	22/18639	0.0909090909090909	0.678868006993007	0.813975349403297	1
GO:0050321	tau-protein kinase activity	2/2496	22/18639	0.0909090909090909	0.678868006993007	0.813975349403297	1
GO:0140784	metal ion sensor activity	2/2496	22/18639	0.0909090909090909	0.678868006993007	0.813975349403297	1
GO:0008237	metallopeptidase activity	21/2496	184/18639	0.114130434782609	0.852274508779264	0.814919877304607	1
GO:0001727	lipid kinase activity	4/2496	41/18639	0.0975609756097561	0.728541275797373	0.817555885888412	1
GO:0016877	ligase activity, forming carbon-sulfur bonds	4/2496	41/18639	0.0975609756097561	0.728541275797373	0.817555885888412	1
GO:0004518	nuclease activity	24/2496	209/18639	0.114832535885167	0.857517482517483	0.819444505640981	1
GO:0001786	phosphatidylserine binding	6/2496	59/18639	0.101694915254237	0.759411668839635	0.819494302144782	1
GO:0015106	bicarbonate transmembrane transporter activity	3/2496	32/18639	0.09375	0.700082632211538	0.821372443274471	1
GO:0047498	calcium-dependent phospholipase A2 activity	3/2496	32/18639	0.09375	0.700082632211538	0.821372443274471	1
GO:0160041	neuropeptide activity	3/2496	32/18639	0.09375	0.700082632211538	0.821372443274471	1
GO:0000340	RNA 7-methylguanosine cap binding	1/2496	12/18639	0.0833333333333333	0.622295673076923	0.821966479057247	1
GO:0000995	RNA polymerase III general transcription initiation factor activity	1/2496	12/18639	0.0833333333333333	0.622295673076923	0.821966479057247	1
GO:0003720	telomerase activity	1/2496	12/18639	0.0833333333333333	0.622295673076923	0.821966479057247	1
GO:0004000	adenosine deaminase activity	1/2496	12/18639	0.0833333333333333	0.622295673076923	0.821966479057247	1
GO:0004859	phospholipase inhibitor activity	1/2496	12/18639	0.0833333333333333	0.622295673076923	0.821966479057247	1
GO:0005025	transforming growth factor beta receptor activity, type I	1/2496	12/18639	0.0833333333333333	0.622295673076923	0.821966479057247	1
GO:0005026	transforming growth factor beta receptor activity, type II	1/2496	12/18639	0.0833333333333333	0.622295673076923	0.821966479057247	1
GO:0005436	sodium:phosphate symporter activity	1/2496	12/18639	0.0833333333333333	0.622295673076923	0.821966479057247	1
GO:0015132	prostaglandin transmembrane transporter activity	1/2496	12/18639	0.0833333333333333	0.622295673076923	0.821966479057247	1
GO:0016273	arginine N-methyltransferase activity	1/2496	12/18639	0.0833333333333333	0.622295673076923	0.821966479057247	1
GO:0016274	protein-arginine N-methyltransferase activity	1/2496	12/18639	0.0833333333333333	0.622295673076923	0.821966479057247	1
GO:0016361	activin receptor activity, type I	1/2496	12/18639	0.0833333333333333	0.622295673076923	0.821966479057247	1
GO:0016362	activin receptor activity, type II	1/2496	12/18639	0.0833333333333333	0.622295673076923	0.821966479057247	1
GO:0016840	carbon-nitrogen lyase activity	1/2496	12/18639	0.0833333333333333	0.622295673076923	0.821966479057247	1
GO:0017002	activin receptor activity	1/2496	12/18639	0.0833333333333333	0.622295673076923	0.821966479057247	1
GO:0017166	vinculin binding	1/2496	12/18639	0.0833333333333333	0.622295673076923	0.821966479057247	1
GO:0034452	dynactin binding	1/2496	12/18639	0.0833333333333333	0.622295673076923	0.821966479057247	1
GO:0036009	protein-glutamine N-methyltransferase activity	1/2496	12/18639	0.0833333333333333	0.622295673076923	0.821966479057247	1
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	1/2496	12/18639	0.0833333333333333	0.622295673076923	0.821966479057247	1
GO:0070410	co-SMAD binding	1/2496	12/18639	0.0833333333333333	0.622295673076923	0.821966479057247	1
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	1/2496	12/18639	0.0833333333333333	0.622295673076923	0.821966479057247	1
GO:0140829	bicarbonate:monoatomic anion antiporter activity	1/2496	12/18639	0.0833333333333333	0.622295673076923	0.821966479057247	1
GO:0140900	chloride:bicarbonate antiporter activity	1/2496	12/18639	0.0833333333333333	0.622295673076923	0.821966479057247	1
GO:1990247	N6-methyladenosine-containing RNA reader activity	1/2496	12/18639	0.0833333333333333	0.622295673076923	0.821966479057247	1
GO:1990459	transferrin receptor binding	1/2496	12/18639	0.0833333333333333	0.622295673076923	0.821966479057247	1
GO:1990841	promoter-specific chromatin binding	7/2496	68/18639	0.102941176470588	0.76871818438914	0.822574802559394	1
GO:0016779	nucleotidyltransferase activity	15/2496	136/18639	0.110294117647059	0.823626626131222	0.825185446015528	1
GO:0051020	GTPase binding	37/2496	315/18639	0.117460317460317	0.877140567765568	0.828080638968383	1
GO:0001098	basal transcription machinery binding	6/2496	60/18639	0.1	0.746754807692308	0.831766364372497	1
GO:0001099	basal RNA polymerase II transcription machinery binding	6/2496	60/18639	0.1	0.746754807692308	0.831766364372497	1
GO:0004520	DNA endonuclease activity	4/2496	42/18639	0.0952380952380952	0.711195054945055	0.832093459294613	1
GO:0019894	kinesin binding	4/2496	42/18639	0.0952380952380952	0.711195054945055	0.832093459294613	1
GO:0008171	O-methyltransferase activity	2/2496	23/18639	0.0869565217391304	0.649352006688963	0.833247595803766	1
GO:0016493	C-C chemokine receptor activity	2/2496	23/18639	0.0869565217391304	0.649352006688963	0.833247595803766	1
GO:0043274	phospholipase binding	2/2496	23/18639	0.0869565217391304	0.649352006688963	0.833247595803766	1
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	2/2496	23/18639	0.0869565217391304	0.649352006688963	0.833247595803766	1
GO:0016279	protein-lysine N-methyltransferase activity	7/2496	69/18639	0.101449275362319	0.757577341137124	0.833949470307613	1
GO:0008276	protein methyltransferase activity	10/2496	95/18639	0.105263157894737	0.786057692307692	0.834644869571676	1
GO:0071889	14-3-3 protein binding	3/2496	33/18639	0.0909090909090909	0.678868006993007	0.837326619410445	1
GO:0022836	gated channel activity	37/2496	318/18639	0.116352201257862	0.868865656748911	0.844115986688481	1
GO:0016278	lysine N-methyltransferase activity	7/2496	70/18639	0.1	0.746754807692308	0.844737655904863	1
GO:0003964	RNA-directed DNA polymerase activity	1/2496	13/18639	0.0769230769230769	0.574426775147929	0.845822798822809	1
GO:0004535	poly(A)-specific ribonuclease activity	1/2496	13/18639	0.0769230769230769	0.574426775147929	0.845822798822809	1
GO:0004993	G protein-coupled serotonin receptor activity	1/2496	13/18639	0.0769230769230769	0.574426775147929	0.845822798822809	1
GO:0008417	fucosyltransferase activity	1/2496	13/18639	0.0769230769230769	0.574426775147929	0.845822798822809	1
GO:0009982	pseudouridine synthase activity	1/2496	13/18639	0.0769230769230769	0.574426775147929	0.845822798822809	1
GO:0032396	inhibitory MHC class I receptor activity	1/2496	13/18639	0.0769230769230769	0.574426775147929	0.845822798822809	1
GO:0046974	histone H3K9 methyltransferase activity	1/2496	13/18639	0.0769230769230769	0.574426775147929	0.845822798822809	1
GO:0051011	microtubule minus-end binding	1/2496	13/18639	0.0769230769230769	0.574426775147929	0.845822798822809	1
GO:0061459	L-arginine transmembrane transporter activity	1/2496	13/18639	0.0769230769230769	0.574426775147929	0.845822798822809	1
GO:0070123	transforming growth factor beta receptor activity, type III	1/2496	13/18639	0.0769230769230769	0.574426775147929	0.845822798822809	1
GO:0071837	HMG box domain binding	1/2496	13/18639	0.0769230769230769	0.574426775147929	0.845822798822809	1
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/2496	13/18639	0.0769230769230769	0.574426775147929	0.845822798822809	1
GO:0140852	histone ubiquitin ligase activity	1/2496	13/18639	0.0769230769230769	0.574426775147929	0.845822798822809	1
GO:1901338	catecholamine binding	1/2496	13/18639	0.0769230769230769	0.574426775147929	0.845822798822809	1
GO:0015149	hexose transmembrane transporter activity	2/2496	24/18639	0.0833333333333333	0.622295673076923	0.850696575661691	1
GO:0035035	histone acetyltransferase binding	2/2496	24/18639	0.0833333333333333	0.622295673076923	0.850696575661691	1
GO:0050431	transforming growth factor beta binding	2/2496	24/18639	0.0833333333333333	0.622295673076923	0.850696575661691	1
GO:0050699	WW domain binding	2/2496	24/18639	0.0833333333333333	0.622295673076923	0.850696575661691	1
GO:0055056	D-glucose transmembrane transporter activity	2/2496	24/18639	0.0833333333333333	0.622295673076923	0.850696575661691	1
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	3/2496	34/18639	0.0882352941176471	0.658901300904977	0.852034497414775	1
GO:0019825	oxygen binding	3/2496	34/18639	0.0882352941176471	0.658901300904977	0.852034497414775	1
GO:0017171	serine hydrolase activity	22/2496	198/18639	0.111111111111111	0.829727564102564	0.854509102482523	1
GO:0016251	RNA polymerase II general transcription initiation factor activity	5/2496	53/18639	0.0943396226415094	0.704485667634253	0.855094913229328	1
GO:0034212	protein N-acetyltransferase activity	5/2496	53/18639	0.0943396226415094	0.704485667634253	0.855094913229328	1
GO:0000049	tRNA binding	8/2496	80/18639	0.1	0.746754807692308	0.856543988052044	1
GO:0001223	transcription coactivator binding	4/2496	44/18639	0.0909090909090909	0.678868006993007	0.858273101222682	1
GO:0101005	deubiquitinase activity	12/2496	115/18639	0.104347826086957	0.779222408026756	0.859579684291452	1
GO:1901682	sulfur compound transmembrane transporter activity	6/2496	63/18639	0.0952380952380952	0.711195054945055	0.864596671960737	1
GO:0004623	phospholipase A2 activity	3/2496	35/18639	0.0857142857142857	0.640075549450549	0.865567642459447	1
GO:0005343	organic acid:sodium symporter activity	3/2496	35/18639	0.0857142857142857	0.640075549450549	0.865567642459447	1
GO:0043015	gamma-tubulin binding	3/2496	35/18639	0.0857142857142857	0.640075549450549	0.865567642459447	1
GO:0022832	voltage-gated channel activity	19/2496	175/18639	0.108571428571429	0.810762362637363	0.866056598416804	1
GO:0140463	chromatin-protein adaptor activity	5/2496	54/18639	0.0925925925925926	0.691439636752137	0.866090093864732	1
GO:0003707	nuclear steroid receptor activity	2/2496	25/18639	0.08	0.597403846153846	0.866464785270469	1
GO:0005251	delayed rectifier potassium channel activity	2/2496	25/18639	0.08	0.597403846153846	0.866464785270469	1
GO:0015645	fatty acid ligase activity	2/2496	25/18639	0.08	0.597403846153846	0.866464785270469	1
GO:0019706	protein-cysteine S-palmitoyltransferase activity	2/2496	25/18639	0.08	0.597403846153846	0.866464785270469	1
GO:0019707	protein-cysteine S-acyltransferase activity	2/2496	25/18639	0.08	0.597403846153846	0.866464785270469	1
GO:0042974	nuclear retinoic acid receptor binding	2/2496	25/18639	0.08	0.597403846153846	0.866464785270469	1
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	2/2496	25/18639	0.08	0.597403846153846	0.866464785270469	1
GO:0120515	fatty acid-CoA ligase activity	2/2496	25/18639	0.08	0.597403846153846	0.866464785270469	1
GO:0008174	mRNA methyltransferase activity	1/2496	14/18639	0.0714285714285714	0.533396291208791	0.86648350397358	1
GO:0008331	high voltage-gated calcium channel activity	1/2496	14/18639	0.0714285714285714	0.533396291208791	0.86648350397358	1
GO:0008559	ABC-type xenobiotic transporter activity	1/2496	14/18639	0.0714285714285714	0.533396291208791	0.86648350397358	1
GO:0015926	glucosidase activity	1/2496	14/18639	0.0714285714285714	0.533396291208791	0.86648350397358	1
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	1/2496	14/18639	0.0714285714285714	0.533396291208791	0.86648350397358	1
GO:0019992	diacylglycerol binding	1/2496	14/18639	0.0714285714285714	0.533396291208791	0.86648350397358	1
GO:0031404	chloride ion binding	1/2496	14/18639	0.0714285714285714	0.533396291208791	0.86648350397358	1
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	1/2496	14/18639	0.0714285714285714	0.533396291208791	0.86648350397358	1
GO:0061665	SUMO ligase activity	1/2496	14/18639	0.0714285714285714	0.533396291208791	0.86648350397358	1
GO:0098821	BMP receptor activity	1/2496	14/18639	0.0714285714285714	0.533396291208791	0.86648350397358	1
GO:1901474	azole transmembrane transporter activity	1/2496	14/18639	0.0714285714285714	0.533396291208791	0.86648350397358	1
GO:0140996	histone H3 kinase activity	41/2496	357/18639	0.11484593837535	0.857617566257272	0.875625790656458	1
GO:0015079	potassium ion transmembrane transporter activity	17/2496	160/18639	0.10625	0.793426983173077	0.876934208838089	1
GO:0000993	RNA polymerase II complex binding	3/2496	36/18639	0.0833333333333333	0.622295673076923	0.877997581758123	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	3/2496	36/18639	0.0833333333333333	0.622295673076923	0.877997581758123	1
GO:0005484	SNAP receptor activity	3/2496	36/18639	0.0833333333333333	0.622295673076923	0.877997581758123	1
GO:0008236	serine-type peptidase activity	21/2496	194/18639	0.108247422680412	0.808342833068993	0.879409083476323	1
GO:0001637	G protein-coupled chemoattractant receptor activity	2/2496	26/18639	0.0769230769230769	0.574426775147929	0.880689267900786	1
GO:0004950	chemokine receptor activity	2/2496	26/18639	0.0769230769230769	0.574426775147929	0.880689267900786	1
GO:0015145	monosaccharide transmembrane transporter activity	2/2496	26/18639	0.0769230769230769	0.574426775147929	0.880689267900786	1
GO:0034237	protein kinase A regulatory subunit binding	2/2496	26/18639	0.0769230769230769	0.574426775147929	0.880689267900786	1
GO:0070412	R-SMAD binding	2/2496	26/18639	0.0769230769230769	0.574426775147929	0.880689267900786	1
GO:0019783	ubiquitin-like protein peptidase activity	13/2496	127/18639	0.102362204724409	0.76439468503937	0.88377014841106	1
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	1/2496	15/18639	0.0666666666666667	0.497836538461538	0.884376506608852	1
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	1/2496	15/18639	0.0666666666666667	0.497836538461538	0.884376506608852	1
GO:0015116	sulfate transmembrane transporter activity	1/2496	15/18639	0.0666666666666667	0.497836538461538	0.884376506608852	1
GO:0015250	water channel activity	1/2496	15/18639	0.0666666666666667	0.497836538461538	0.884376506608852	1
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/2496	15/18639	0.0666666666666667	0.497836538461538	0.884376506608852	1
GO:0017081	chloride channel regulator activity	1/2496	15/18639	0.0666666666666667	0.497836538461538	0.884376506608852	1
GO:0048531	beta-1,3-galactosyltransferase activity	1/2496	15/18639	0.0666666666666667	0.497836538461538	0.884376506608852	1
GO:0061578	K63-linked deubiquitinase activity	1/2496	15/18639	0.0666666666666667	0.497836538461538	0.884376506608852	1
GO:0140161	monocarboxylate:sodium symporter activity	1/2496	15/18639	0.0666666666666667	0.497836538461538	0.884376506608852	1
GO:0140776	protein-containing complex destabilizing activity	1/2496	15/18639	0.0666666666666667	0.497836538461538	0.884376506608852	1
GO:0030170	pyridoxal phosphate binding	5/2496	56/18639	0.0892857142857143	0.666745364010989	0.885976518882698	1
GO:0099094	ligand-gated monoatomic cation channel activity	14/2496	136/18639	0.102941176470588	0.76871818438914	0.886270024413541	1
GO:0035173	histone kinase activity	41/2496	360/18639	0.113888888888889	0.850470753205128	0.887665882532849	1
GO:0042805	actinin binding	3/2496	37/18639	0.0810810810810811	0.605476871101871	0.889394964842541	1
GO:0061733	protein-lysine-acetyltransferase activity	4/2496	47/18639	0.0851063829787234	0.635536006546645	0.89096881503202	1
GO:0140938	histone H3 methyltransferase activity	4/2496	47/18639	0.0851063829787234	0.635536006546645	0.89096881503202	1
GO:0046982	protein heterodimerization activity	42/2496	369/18639	0.113821138211382	0.849964821763602	0.891043655550508	1
GO:0008395	steroid hydroxylase activity	2/2496	27/18639	0.0740740740740741	0.553151709401709	0.893500518797407	1
GO:0016405	CoA-ligase activity	2/2496	27/18639	0.0740740740740741	0.553151709401709	0.893500518797407	1
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	2/2496	27/18639	0.0740740740740741	0.553151709401709	0.893500518797407	1
GO:0015293	symporter activity	15/2496	146/18639	0.102739726027397	0.767213843519494	0.894579883459278	1
GO:0070279	vitamin B6 binding	5/2496	57/18639	0.087719298245614	0.655048076923077	0.894932161697138	1
GO:0141003	histone H2AX kinase activity	40/2496	354/18639	0.112994350282486	0.84379074315515	0.895676860368598	1
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	1/2496	16/18639	0.0625	0.466721754807692	0.899872438712821	1
GO:0005024	transforming growth factor beta receptor activity	1/2496	16/18639	0.0625	0.466721754807692	0.899872438712821	1
GO:0008296	3'-5'-DNA exonuclease activity	1/2496	16/18639	0.0625	0.466721754807692	0.899872438712821	1
GO:0015378	sodium:chloride symporter activity	1/2496	16/18639	0.0625	0.466721754807692	0.899872438712821	1
GO:0015385	sodium:proton antiporter activity	1/2496	16/18639	0.0625	0.466721754807692	0.899872438712821	1
GO:0015562	efflux transmembrane transporter activity	1/2496	16/18639	0.0625	0.466721754807692	0.899872438712821	1
GO:0055102	lipase inhibitor activity	1/2496	16/18639	0.0625	0.466721754807692	0.899872438712821	1
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	1/2496	16/18639	0.0625	0.466721754807692	0.899872438712821	1
GO:0140327	flippase activity	1/2496	16/18639	0.0625	0.466721754807692	0.899872438712821	1
GO:0042054	histone methyltransferase activity	6/2496	67/18639	0.0895522388059701	0.668735648679678	0.899924289888917	1
GO:0005244	voltage-gated monoatomic ion channel activity	18/2496	173/18639	0.104046242774566	0.776970320142286	0.901664076034104	1
GO:0140030	modification-dependent protein binding	18/2496	173/18639	0.104046242774566	0.776970320142286	0.901664076034104	1
GO:0046966	nuclear thyroid hormone receptor binding	2/2496	28/18639	0.0714285714285714	0.533396291208791	0.90502178099528	1
GO:0051119	sugar transmembrane transporter activity	2/2496	28/18639	0.0714285714285714	0.533396291208791	0.90502178099528	1
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	12/2496	122/18639	0.0983606557377049	0.734512925598991	0.906090024278538	1
GO:0003777	microtubule motor activity	6/2496	68/18639	0.0882352941176471	0.658901300904977	0.907409724146613	1
GO:0140223	general transcription initiation factor activity	6/2496	68/18639	0.0882352941176471	0.658901300904977	0.907409724146613	1
GO:0004896	cytokine receptor activity	9/2496	96/18639	0.09375	0.700082632211538	0.910228439771016	1
GO:0004879	nuclear receptor activity	5/2496	59/18639	0.0847457627118644	0.632843057366362	0.911029796400475	1
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	1/2496	17/18639	0.0588235294117647	0.439267533936652	0.913292316980167	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/2496	17/18639	0.0588235294117647	0.439267533936652	0.913292316980167	1
GO:0045125	bioactive lipid receptor activity	1/2496	17/18639	0.0588235294117647	0.439267533936652	0.913292316980167	1
GO:1990226	histone methyltransferase binding	1/2496	17/18639	0.0588235294117647	0.439267533936652	0.913292316980167	1
GO:0008080	N-acetyltransferase activity	6/2496	69/18639	0.0869565217391304	0.649352006688963	0.914405938797947	1
GO:0004674	protein serine/threonine kinase activity	49/2496	433/18639	0.113163972286374	0.84505740362409	0.914611279329194	1
GO:0004181	metallocarboxypeptidase activity	2/2496	29/18639	0.0689655172413793	0.515003315649867	0.915368646985738	1
GO:0000149	SNARE binding	10/2496	106/18639	0.0943396226415094	0.704485667634253	0.915913996323727	1
GO:0098531	ligand-modulated transcription factor activity	5/2496	60/18639	0.0833333333333333	0.622295673076923	0.918235562948473	1
GO:0015294	solute:monoatomic cation symporter activity	11/2496	116/18639	0.0948275862068965	0.708129559018568	0.921297669219062	1
GO:0015276	ligand-gated monoatomic ion channel activity	19/2496	186/18639	0.102150537634409	0.762814050868486	0.921483556840758	1
GO:0005249	voltage-gated potassium channel activity	9/2496	98/18639	0.0918367346938776	0.68579523155416	0.921636994150939	1
GO:0008170	N-methyltransferase activity	9/2496	98/18639	0.0918367346938776	0.68579523155416	0.921636994150939	1
GO:0005272	sodium channel activity	4/2496	51/18639	0.0784313725490196	0.585690045248869	0.924175877996188	1
GO:0035925	mRNA 3'-UTR AU-rich region binding	2/2496	30/18639	0.0666666666666667	0.497836538461538	0.92464889699872	1
GO:0000400	four-way junction DNA binding	1/2496	18/18639	0.0555555555555556	0.414863782051282	0.924914182344656	1
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/2496	18/18639	0.0555555555555556	0.414863782051282	0.924914182344656	1
GO:0005372	water transmembrane transporter activity	1/2496	18/18639	0.0555555555555556	0.414863782051282	0.924914182344656	1
GO:0015280	ligand-gated sodium channel activity	1/2496	18/18639	0.0555555555555556	0.414863782051282	0.924914182344656	1
GO:0015373	monoatomic anion:sodium symporter activity	1/2496	18/18639	0.0555555555555556	0.414863782051282	0.924914182344656	1
GO:0022851	GABA-gated chloride ion channel activity	1/2496	18/18639	0.0555555555555556	0.414863782051282	0.924914182344656	1
GO:0032393	MHC class I receptor activity	1/2496	18/18639	0.0555555555555556	0.414863782051282	0.924914182344656	1
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	1/2496	18/18639	0.0555555555555556	0.414863782051282	0.924914182344656	1
GO:0008227	G protein-coupled amine receptor activity	3/2496	41/18639	0.0731707317073171	0.54640595684803	0.926007466397251	1
GO:0004843	cysteine-type deubiquitinase activity	10/2496	108/18639	0.0925925925925926	0.691439636752137	0.926292260194894	1
GO:0022834	ligand-gated channel activity	19/2496	188/18639	0.101063829787234	0.754699007774141	0.92916966727043	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	2/2496	31/18639	0.0645161290322581	0.48177729528536	0.932962517713902	1
GO:0016878	acid-thiol ligase activity	2/2496	31/18639	0.0645161290322581	0.48177729528536	0.932962517713902	1
GO:0070273	phosphatidylinositol-4-phosphate binding	2/2496	31/18639	0.0645161290322581	0.48177729528536	0.932962517713902	1
GO:0004402	histone acetyltransferase activity	3/2496	42/18639	0.0714285714285714	0.533396291208791	0.933231620789762	1
GO:0043175	RNA polymerase core enzyme binding	3/2496	42/18639	0.0714285714285714	0.533396291208791	0.933231620789762	1
GO:0004890	GABA-A receptor activity	1/2496	19/18639	0.0526315789473684	0.393028846153846	0.93497885131344	1
GO:0022840	leak channel activity	1/2496	19/18639	0.0526315789473684	0.393028846153846	0.93497885131344	1
GO:0022842	narrow pore channel activity	1/2496	19/18639	0.0526315789473684	0.393028846153846	0.93497885131344	1
GO:0030506	ankyrin binding	1/2496	19/18639	0.0526315789473684	0.393028846153846	0.93497885131344	1
GO:0034987	immunoglobulin receptor binding	1/2496	19/18639	0.0526315789473684	0.393028846153846	0.93497885131344	1
GO:0042800	histone H3K4 methyltransferase activity	1/2496	19/18639	0.0526315789473684	0.393028846153846	0.93497885131344	1
GO:0042834	peptidoglycan binding	1/2496	19/18639	0.0526315789473684	0.393028846153846	0.93497885131344	1
GO:0099589	serotonin receptor activity	1/2496	19/18639	0.0526315789473684	0.393028846153846	0.93497885131344	1
GO:1990380	K48-linked deubiquitinase activity	1/2496	19/18639	0.0526315789473684	0.393028846153846	0.93497885131344	1
GO:0031490	chromatin DNA binding	12/2496	128/18639	0.09375	0.700082632211538	0.935027920577963	1
GO:0005544	calcium-dependent phospholipid binding	4/2496	53/18639	0.0754716981132075	0.563588534107402	0.937099900103169	1
GO:0015631	tubulin binding	42/2496	385/18639	0.109090909090909	0.814641608391608	0.939067127338204	1
GO:0005245	voltage-gated calcium channel activity	3/2496	43/18639	0.0697674418604651	0.520991726296959	0.939800135682155	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	3/2496	43/18639	0.0697674418604651	0.520991726296959	0.939800135682155	1
GO:0042910	xenobiotic transmembrane transporter activity	2/2496	32/18639	0.0625	0.466721754807692	0.940401856009864	1
GO:0070717	poly-purine tract binding	2/2496	32/18639	0.0625	0.466721754807692	0.940401856009864	1
GO:0106310	protein serine kinase activity	39/2496	361/18639	0.10803324099723	0.806743421052632	0.941129620833956	1
GO:0001217	DNA-binding transcription repressor activity	29/2496	278/18639	0.10431654676259	0.778988828168235	0.943251654240573	1
GO:0030627	pre-mRNA 5'-splice site binding	1/2496	20/18639	0.05	0.373377403846154	0.94369489788281	1
GO:0140664	ATP-dependent DNA damage sensor activity	1/2496	20/18639	0.05	0.373377403846154	0.94369489788281	1
GO:0016410	N-acyltransferase activity	8/2496	94/18639	0.0851063829787234	0.635536006546645	0.946428108427434	1
GO:0005096	GTPase activator activity	28/2496	271/18639	0.103321033210332	0.771554782855521	0.947000857224522	1
GO:0019239	deaminase activity	2/2496	33/18639	0.0606060606060606	0.452578671328671	0.947051871274343	1
GO:0004252	serine-type endopeptidase activity	17/2496	176/18639	0.0965909090909091	0.72129725743007	0.947312103505195	1
GO:0005179	hormone activity	12/2496	132/18639	0.0909090909090909	0.678868006993007	0.949746931722571	1
GO:0035402	histone H3T11 kinase activity	25/2496	247/18639	0.101214574898785	0.755824704142012	0.951047248072325	1
GO:0035403	histone H3T6 kinase activity	25/2496	247/18639	0.101214574898785	0.755824704142012	0.951047248072325	1
GO:0051010	microtubule plus-end binding	1/2496	21/18639	0.0476190476190476	0.355597527472527	0.951242968933054	1
GO:1904047	S-adenosyl-L-methionine binding	1/2496	21/18639	0.0476190476190476	0.355597527472527	0.951242968933054	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	4/2496	56/18639	0.0714285714285714	0.533396291208791	0.952759307976092	1
GO:0170055	lipid transmembrane transporter activity	4/2496	56/18639	0.0714285714285714	0.533396291208791	0.952759307976092	1
GO:0090482	vitamin transmembrane transporter activity	2/2496	34/18639	0.0588235294117647	0.439267533936652	0.952990457140566	1
GO:0031267	small GTPase binding	29/2496	283/18639	0.102473498233216	0.765225774667029	0.954938263315455	1
GO:0008013	beta-catenin binding	9/2496	106/18639	0.0849056603773585	0.634037100870827	0.955669041311849	1
GO:0140597	protein carrier chaperone	18/2496	188/18639	0.0957446808510638	0.714978007364975	0.955978259738795	1
GO:0030594	neurotransmitter receptor activity	8/2496	97/18639	0.0824742268041237	0.615880253766852	0.957378183024778	1
GO:0008649	rRNA methyltransferase activity	1/2496	22/18639	0.0454545454545455	0.339434003496503	0.957779522243995	1
GO:0030021	extracellular matrix structural constituent conferring compression resistance	1/2496	22/18639	0.0454545454545455	0.339434003496503	0.957779522243995	1
GO:0032931	histone H3K56 acetyltransferase activity	1/2496	22/18639	0.0454545454545455	0.339434003496503	0.957779522243995	1
GO:0043992	histone H3K9 acetyltransferase activity	1/2496	22/18639	0.0454545454545455	0.339434003496503	0.957779522243995	1
GO:0043993	histone H3K18 acetyltransferase activity	1/2496	22/18639	0.0454545454545455	0.339434003496503	0.957779522243995	1
GO:0043994	histone H3K23 acetyltransferase activity	1/2496	22/18639	0.0454545454545455	0.339434003496503	0.957779522243995	1
GO:0043999	histone H2AK5 acetyltransferase activity	1/2496	22/18639	0.0454545454545455	0.339434003496503	0.957779522243995	1
GO:0044012	histone H2AK9 acetyltransferase activity	1/2496	22/18639	0.0454545454545455	0.339434003496503	0.957779522243995	1
GO:0044014	histone H2BK5 acetyltransferase activity	1/2496	22/18639	0.0454545454545455	0.339434003496503	0.957779522243995	1
GO:0044015	histone H2BK12 acetyltransferase activity	1/2496	22/18639	0.0454545454545455	0.339434003496503	0.957779522243995	1
GO:0044016	histone H3K4 acetyltransferase activity	1/2496	22/18639	0.0454545454545455	0.339434003496503	0.957779522243995	1
GO:0044017	histone H3K27 acetyltransferase activity	1/2496	22/18639	0.0454545454545455	0.339434003496503	0.957779522243995	1
GO:0044018	histone H3K36 acetyltransferase activity	1/2496	22/18639	0.0454545454545455	0.339434003496503	0.957779522243995	1
GO:0046972	histone H4K16 acetyltransferase activity	1/2496	22/18639	0.0454545454545455	0.339434003496503	0.957779522243995	1
GO:0140908	histone H3K122 acetyltransferase activity	1/2496	22/18639	0.0454545454545455	0.339434003496503	0.957779522243995	1
GO:0008017	microtubule binding	28/2496	276/18639	0.101449275362319	0.757577341137124	0.958158777038358	1
GO:0034061	DNA polymerase activity	2/2496	35/18639	0.0571428571428571	0.426717032967033	0.958288809545482	1
GO:0019787	ubiquitin-like protein transferase activity	52/2496	479/18639	0.108559498956159	0.810673277661796	0.960209380940671	1
GO:0099095	ligand-gated monoatomic anion channel activity	3/2496	47/18639	0.0638297872340425	0.476652004909984	0.960520605678464	1
GO:0016755	aminoacyltransferase activity	54/2496	496/18639	0.108870967741935	0.812999185794045	0.96087449063808	1
GO:0008408	3'-5' exonuclease activity	4/2496	58/18639	0.0689655172413793	0.515003315649867	0.961112589034526	1
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	24/2496	243/18639	0.0987654320987654	0.737535612535613	0.961283218441751	1
GO:0003887	DNA-directed DNA polymerase activity	1/2496	23/18639	0.0434782608695652	0.324676003344482	0.963440064354915	1
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	1/2496	23/18639	0.0434782608695652	0.324676003344482	0.963440064354915	1
GO:0005212	structural constituent of eye lens	1/2496	23/18639	0.0434782608695652	0.324676003344482	0.963440064354915	1
GO:0016917	GABA receptor activity	1/2496	23/18639	0.0434782608695652	0.324676003344482	0.963440064354915	1
GO:0044013	histone H2B acetyltransferase activity	1/2496	23/18639	0.0434782608695652	0.324676003344482	0.963440064354915	1
GO:0140102	catalytic activity, acting on a rRNA	1/2496	23/18639	0.0434782608695652	0.324676003344482	0.963440064354915	1
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	1/2496	23/18639	0.0434782608695652	0.324676003344482	0.963440064354915	1
GO:0004676	3-phosphoinositide-dependent protein kinase activity	24/2496	245/18639	0.0979591836734694	0.731514913657771	0.965109690786062	1
GO:0004711	ribosomal protein S6 kinase activity	24/2496	245/18639	0.0979591836734694	0.731514913657771	0.965109690786062	1
GO:0035175	histone H3S10 kinase activity	24/2496	245/18639	0.0979591836734694	0.731514913657771	0.965109690786062	1
GO:0035979	histone H2AXS139 kinase activity	24/2496	245/18639	0.0979591836734694	0.731514913657771	0.965109690786062	1
GO:0044022	histone H3S28 kinase activity	24/2496	245/18639	0.0979591836734694	0.731514913657771	0.965109690786062	1
GO:0044023	histone H4S1 kinase activity	24/2496	245/18639	0.0979591836734694	0.731514913657771	0.965109690786062	1
GO:0044024	histone H2AS1 kinase activity	24/2496	245/18639	0.0979591836734694	0.731514913657771	0.965109690786062	1
GO:0044025	histone H2BS14 kinase activity	24/2496	245/18639	0.0979591836734694	0.731514913657771	0.965109690786062	1
GO:0072354	histone H3T3 kinase activity	24/2496	245/18639	0.0979591836734694	0.731514913657771	0.965109690786062	1
GO:0072371	histone H2AS121 kinase activity	24/2496	245/18639	0.0979591836734694	0.731514913657771	0.965109690786062	1
GO:0072518	Rho-dependent protein serine/threonine kinase activity	24/2496	245/18639	0.0979591836734694	0.731514913657771	0.965109690786062	1
GO:0140823	histone H2BS36 kinase activity	24/2496	245/18639	0.0979591836734694	0.731514913657771	0.965109690786062	1
GO:0140855	histone H3S57 kinase activity	24/2496	245/18639	0.0979591836734694	0.731514913657771	0.965109690786062	1
GO:0140995	histone H2A kinase activity	24/2496	245/18639	0.0979591836734694	0.731514913657771	0.965109690786062	1
GO:0140997	histone H4 kinase activity	24/2496	245/18639	0.0979591836734694	0.731514913657771	0.965109690786062	1
GO:0140998	histone H2B kinase activity	24/2496	245/18639	0.0979591836734694	0.731514913657771	0.965109690786062	1
GO:1990244	histone H2AT120 kinase activity	24/2496	245/18639	0.0979591836734694	0.731514913657771	0.965109690786062	1
GO:0004677	DNA-dependent protein kinase activity	24/2496	246/18639	0.0975609756097561	0.728541275797373	0.966895985130974	1
GO:0140857	histone H3T45 kinase activity	24/2496	246/18639	0.0975609756097561	0.728541275797373	0.966895985130974	1
GO:0030280	structural constituent of skin epidermis	2/2496	37/18639	0.0540540540540541	0.403651247401247	0.967218500550579	1
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	4/2496	60/18639	0.0666666666666667	0.497836538461538	0.968077789025144	1
GO:0043998	histone H2A acetyltransferase activity	1/2496	24/18639	0.0416666666666667	0.311147836538462	0.968341955167664	1
GO:0070840	dynein complex binding	1/2496	24/18639	0.0416666666666667	0.311147836538462	0.968341955167664	1
GO:0140612	DNA damage sensor activity	1/2496	24/18639	0.0416666666666667	0.311147836538462	0.968341955167664	1
GO:0140767	enzyme-substrate adaptor activity	12/2496	139/18639	0.0863309352517986	0.644680409518539	0.968589143801174	1
GO:0004679	AMP-activated protein kinase activity	24/2496	248/18639	0.0967741935483871	0.72266594292804	0.970229715086388	1
GO:0015271	outward rectifier potassium channel activity	1/2496	25/18639	0.04	0.298701923076923	0.972586837246713	1
GO:0047617	fatty acyl-CoA hydrolase activity	1/2496	25/18639	0.04	0.298701923076923	0.972586837246713	1
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	26/2496	268/18639	0.0970149253731343	0.724463619402985	0.973856143712868	1
GO:0016597	amino acid binding	3/2496	51/18639	0.0588235294117647	0.439267533936652	0.974392306872197	1
GO:0022843	voltage-gated monoatomic cation channel activity	12/2496	143/18639	0.0839160839160839	0.626647391070468	0.976248607751729	1
GO:0005112	Notch binding	1/2496	26/18639	0.0384615384615385	0.287213387573965	0.97626274002055	1
GO:0008143	poly(A) binding	1/2496	26/18639	0.0384615384615385	0.287213387573965	0.97626274002055	1
GO:0016289	acyl-CoA hydrolase activity	1/2496	26/18639	0.0384615384615385	0.287213387573965	0.97626274002055	1
GO:0022824	transmitter-gated monoatomic ion channel activity	4/2496	63/18639	0.0634920634920635	0.474130036630037	0.976373700610786	1
GO:0022835	transmitter-gated channel activity	4/2496	63/18639	0.0634920634920635	0.474130036630037	0.976373700610786	1
GO:0005267	potassium channel activity	10/2496	124/18639	0.0806451612903226	0.6022216191067	0.976401907550567	1
GO:0035064	methylated histone binding	5/2496	74/18639	0.0675675675675676	0.504564059251559	0.97685006464233	1
GO:0004532	RNA exonuclease activity	2/2496	40/18639	0.05	0.373377403846154	0.977250822278533	1
GO:0015144	carbohydrate transmembrane transporter activity	2/2496	40/18639	0.05	0.373377403846154	0.977250822278533	1
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	1/2496	27/18639	0.037037037037037	0.276575854700855	0.979445902375287	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	3/2496	53/18639	0.0566037735849057	0.422691400580552	0.979451709449261	1
GO:0140034	methylation-dependent protein binding	5/2496	76/18639	0.0657894736842105	0.491286057692308	0.980871443503377	1
GO:0140097	catalytic activity, acting on DNA	33/2496	336/18639	0.0982142857142857	0.733419900412088	0.981612872325376	1
GO:0036408	histone H3K14 acetyltransferase activity	1/2496	28/18639	0.0357142857142857	0.266698145604396	0.982202351315287	1
GO:0004842	ubiquitin-protein transferase activity	46/2496	449/18639	0.102449888641425	0.765049468905259	0.982639011807052	1
GO:0010484	histone H3 acetyltransferase activity	1/2496	29/18639	0.0344827586206897	0.257501657824934	0.984589269327056	1
GO:0016741	transferase activity, transferring one-carbon groups	19/2496	215/18639	0.0883720930232558	0.659922853309481	0.9849996854942	1
GO:0022839	monoatomic ion-gated channel activity	1/2496	30/18639	0.0333333333333333	0.248918269230769	0.986656178717689	1
GO:0043995	histone H4K5 acetyltransferase activity	1/2496	30/18639	0.0333333333333333	0.248918269230769	0.986656178717689	1
GO:0043996	histone H4K8 acetyltransferase activity	1/2496	30/18639	0.0333333333333333	0.248918269230769	0.986656178717689	1
GO:0043997	histone H4K12 acetyltransferase activity	1/2496	30/18639	0.0333333333333333	0.248918269230769	0.986656178717689	1
GO:0051721	protein phosphatase 2A binding	1/2496	30/18639	0.0333333333333333	0.248918269230769	0.986656178717689	1
GO:0098960	postsynaptic neurotransmitter receptor activity	4/2496	69/18639	0.0579710144927536	0.432901337792642	0.987262888837585	1
GO:0005452	solute:inorganic anion antiporter activity	1/2496	31/18639	0.032258064516129	0.24088864764268	0.988445967417815	1
GO:0042393	histone binding	22/2496	247/18639	0.0890688259109312	0.66512573964497	0.988673564500668	1
GO:0003823	antigen binding	14/2496	174/18639	0.0804597701149425	0.600837201591512	0.989885598253219	1
GO:0008188	neuropeptide receptor activity	2/2496	48/18639	0.0416666666666667	0.311147836538462	0.991578262927534	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	4/2496	73/18639	0.0547945205479452	0.40918071654373	0.991651763221866	1
GO:0001653	peptide receptor activity	9/2496	128/18639	0.0703125	0.525061974158654	0.992299303097228	1
GO:0061630	ubiquitin protein ligase activity	33/2496	353/18639	0.0934844192634561	0.698099395293092	0.992412567953913	1
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	1/2496	34/18639	0.0294117647058824	0.219633766968326	0.992499814452577	1
GO:0052866	phosphatidylinositol phosphate phosphatase activity	1/2496	34/18639	0.0294117647058824	0.219633766968326	0.992499814452577	1
GO:0061659	ubiquitin-like protein ligase activity	35/2496	372/18639	0.0940860215053763	0.702591888957816	0.992901249580299	1
GO:0000175	3'-5'-RNA exonuclease activity	1/2496	35/18639	0.0285714285714286	0.213358516483516	0.993506020479256	1
GO:0010485	histone H4 acetyltransferase activity	1/2496	35/18639	0.0285714285714286	0.213358516483516	0.993506020479256	1
GO:0003724	RNA helicase activity	4/2496	77/18639	0.051948051948052	0.387924575424575	0.994569475489069	1
GO:0008168	methyltransferase activity	16/2496	204/18639	0.0784313725490196	0.585690045248869	0.995339895061032	1
GO:0017046	peptide hormone binding	2/2496	53/18639	0.0377358490566038	0.281794267053701	0.99552717687241	1
GO:0008186	ATP-dependent activity, acting on RNA	4/2496	79/18639	0.0506329113924051	0.378103700097371	0.995631536963916	1
GO:0015370	solute:sodium symporter activity	4/2496	79/18639	0.0506329113924051	0.378103700097371	0.995631536963916	1
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	1/2496	38/18639	0.0263157894736842	0.196514423076923	0.995784918928293	1
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	12/2496	167/18639	0.0718562874251497	0.536590280976509	0.996169478421517	1
GO:0000510	H3-H4 histone complex chaperone activity	10/2496	151/18639	0.0662251655629139	0.49453960774325	0.997397315039786	1
GO:0140584	chromatin extrusion motor activity	10/2496	151/18639	0.0662251655629139	0.49453960774325	0.997397315039786	1
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	10/2496	151/18639	0.0662251655629139	0.49453960774325	0.997397315039786	1
GO:0140849	ATP-dependent H2AZ histone chaperone activity	10/2496	151/18639	0.0662251655629139	0.49453960774325	0.997397315039786	1
GO:0015616	DNA translocase activity	10/2496	152/18639	0.0657894736842105	0.491286057692308	0.997614899741819	1
GO:0140674	ATP-dependent histone chaperone activity	10/2496	152/18639	0.0657894736842105	0.491286057692308	0.997614899741819	1
GO:0061775	cohesin loader activity	10/2496	153/18639	0.065359477124183	0.488075037707391	0.997815077855345	1
GO:0015081	sodium ion transmembrane transporter activity	11/2496	164/18639	0.0670731707317073	0.500872127110694	0.997907910802946	1
GO:0008528	G protein-coupled peptide receptor activity	7/2496	122/18639	0.0573770491803279	0.428465873266078	0.998121751839664	1
GO:0140658	ATP-dependent chromatin remodeler activity	10/2496	158/18639	0.0632911392405063	0.472629625121714	0.998597806115343	1
GO:0003689	DNA clamp loader activity	10/2496	160/18639	0.0625	0.466721754807692	0.998828541579497	1
GO:0140713	histone chaperone activity	10/2496	164/18639	0.0609756097560976	0.455338297373358	0.999185540926537	1
GO:0008173	RNA methyltransferase activity	2/2496	67/18639	0.0298507462686567	0.222911882893226	0.999266124104838	1
GO:0008094	ATP-dependent activity, acting on DNA	14/2496	210/18639	0.0666666666666667	0.497836538461538	0.999399565517747	1
GO:0140101	catalytic activity, acting on a tRNA	7/2496	139/18639	0.0503597122302158	0.376063572219148	0.999659906835551	1
GO:0140098	catalytic activity, acting on RNA	31/2496	387/18639	0.0801033591731266	0.59817568574836	0.999690382641193	1
GO:0003678	DNA helicase activity	2/2496	74/18639	0.027027027027027	0.201825623700624	0.999707251664224	1
GO:0001216	DNA-binding transcription activator activity	41/2496	491/18639	0.0835030549898167	0.623563077706408	0.999835685040106	1
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	39/2496	484/18639	0.0805785123966942	0.601723915289256	0.999923467685675	1
GO:0004386	helicase activity	6/2496	155/18639	0.0387096774193548	0.289066377171216	0.999984649080351	1
GO:0030527	structural constituent of chromatin	1/2496	98/18639	0.0102040816326531	0.0761994701726845	0.999999269109078	1
GO:0003730	mRNA 3'-UTR binding	10/2496	262/18639	0.0381679389312977	0.28502091896653	0.99999996622175	1
GO:0045182	translation regulator activity	14/2496	356/18639	0.0393258426966292	0.293667621002593	0.999999999679564	1
GO:0030371	translation repressor activity	8/2496	329/18639	0.0243161094224924	0.181581716156184	0.999999999999605	1
GO:0004984	olfactory receptor activity	1/2496	419/18639	0.00238663484486874	0.0178223104461171	1	1