ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0030695 GTPase regulator activity 92/1489 489/18639 0.188139059304703 2.35508658588339 5.77159829861223e-15 3.74702780634307e-12 GO:0060589 nucleoside-triphosphatase regulator activity 92/1489 490/18639 0.187755102040816 2.35028028672853 6.56797161497471e-15 3.74702780634307e-12 GO:0005096 GTPase activator activity 53/1489 271/18639 0.195571955719557 2.44813007565939 8.43479357809059e-10 3.20803315753379e-07 GO:0003735 structural constituent of ribosome 38/1489 175/18639 0.217142857142857 2.71815024465125 1.0896184157855e-08 3.10813653102815e-06 GO:0005085 guanyl-nucleotide exchange factor activity 44/1489 230/18639 0.191304347826087 2.39470902560808 4.45838472132662e-08 1.01740339340673e-05 GO:0017124 SH3 domain binding 28/1489 115/18639 0.243478260869565 3.04781148713756 7.17050321889821e-08 1.36359069546048e-05 GO:0009055 electron transfer activity 27/1489 116/18639 0.232758620689655 2.91362520553021 3.26168309489364e-07 5.31654344467663e-05 GO:0038024 cargo receptor activity 19/1489 65/18639 0.292307692307692 3.6590484062613 4.36998893850037e-07 6.23269672353616e-05 GO:0015026 coreceptor activity 18/1489 61/18639 0.295081967213115 3.69377621684704 7.4980708566364e-07 9.50588760824681e-05 GO:0019955 cytokine binding 30/1489 144/18639 0.208333333333333 2.60787441235729 9.49426328748563e-07 0.000108329544110211 GO:0051015 actin filament binding 38/1489 209/18639 0.181818181818182 2.27596312351181 1.35696112185293e-06 0.000138391510394471 GO:0035325 Toll-like receptor binding 8/1489 13/18639 0.615384615384615 7.70325980265537 1.45547600765439e-06 0.000138391510394471 GO:0038187 pattern recognition receptor activity 15/1489 48/18639 0.3125 3.91181161853593 2.80556813900058e-06 0.000246242557430743 GO:0005044 scavenger receptor activity 11/1489 27/18639 0.407407407407407 5.09984329527647 3.19924891555564e-06 0.000260738786617784 GO:0005178 integrin binding 31/1489 161/18639 0.192546583850932 2.41025908421593 3.66037518146659e-06 0.000267421792474113 GO:0015078 proton transmembrane transporter activity 34/1489 185/18639 0.183783783783784 2.30056813025248 3.74999884275706e-06 0.000267421792474113 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 18/1489 68/18639 0.264705882352941 3.31353454746573 4.24584127371692e-06 0.000284970876077118 GO:0022853 active monoatomic ion transmembrane transporter activity 25/1489 118/18639 0.211864406779661 2.65207567358368 5.44507263098835e-06 0.000345157103997651 GO:0098631 cell adhesion mediator activity 19/1489 76/18639 0.25 3.12944929482874 5.8053336830223e-06 0.000348625564859392 GO:0005021 vascular endothelial growth factor receptor activity 15/1489 51/18639 0.294117647058824 3.6817050527397 6.50991877657281e-06 0.000371390866203479 GO:0019838 growth factor binding 27/1489 136/18639 0.198529411764706 2.4851509105993 8.44319230246275e-06 0.000458746781767143 GO:0003779 actin binding 62/1489 443/18639 0.139954853273138 1.75192646753392 1.02042690477242e-05 0.000529230499247879 GO:0038064 collagen receptor activity 15/1489 53/18639 0.283018867924528 3.54277278659858 1.09575532957612e-05 0.000543589926541894 GO:0005004 GPI-linked ephrin receptor activity 14/1489 49/18639 0.285714285714286 3.57651347980428 1.90309026234956e-05 0.000658007875557834 GO:0005008 hepatocyte growth factor receptor activity 14/1489 49/18639 0.285714285714286 3.57651347980428 1.90309026234956e-05 0.000658007875557834 GO:0005009 insulin receptor activity 14/1489 49/18639 0.285714285714286 3.57651347980428 1.90309026234956e-05 0.000658007875557834 GO:0005011 macrophage colony-stimulating factor receptor activity 14/1489 49/18639 0.285714285714286 3.57651347980428 1.90309026234956e-05 0.000658007875557834 GO:0005018 platelet-derived growth factor alpha-receptor activity 14/1489 49/18639 0.285714285714286 3.57651347980428 1.90309026234956e-05 0.000658007875557834 GO:0005020 stem cell factor receptor activity 14/1489 49/18639 0.285714285714286 3.57651347980428 1.90309026234956e-05 0.000658007875557834 GO:0008288 boss receptor activity 14/1489 49/18639 0.285714285714286 3.57651347980428 1.90309026234956e-05 0.000658007875557834 GO:0036332 placental growth factor receptor activity 14/1489 49/18639 0.285714285714286 3.57651347980428 1.90309026234956e-05 0.000658007875557834 GO:0038062 protein tyrosine kinase collagen receptor activity 14/1489 49/18639 0.285714285714286 3.57651347980428 1.90309026234956e-05 0.000658007875557834 GO:0060175 brain-derived neurotrophic factor receptor activity 14/1489 49/18639 0.285714285714286 3.57651347980428 1.90309026234956e-05 0.000658007875557834 GO:0070700 BMP receptor binding 7/1489 13/18639 0.538461538461538 6.74035232732345 2.28437123565044e-05 0.000724702257814759 GO:0005006 epidermal growth factor receptor activity 14/1489 50/18639 0.28 3.50498321020819 2.45032581072546e-05 0.000724702257814759 GO:0005007 fibroblast growth factor receptor activity 14/1489 50/18639 0.28 3.50498321020819 2.45032581072546e-05 0.000724702257814759 GO:0005017 platelet-derived growth factor receptor activity 14/1489 50/18639 0.28 3.50498321020819 2.45032581072546e-05 0.000724702257814759 GO:0005019 platelet-derived growth factor beta-receptor activity 14/1489 50/18639 0.28 3.50498321020819 2.45032581072546e-05 0.000724702257814759 GO:0045296 cadherin binding 49/1489 334/18639 0.146706586826347 1.83644329876178 2.47707169629935e-05 0.000724702257814759 GO:0005543 phospholipid binding 66/1489 497/18639 0.132796780684105 1.66232316666959 2.95490492910756e-05 0.00084288663102793 GO:0005010 insulin-like growth factor receptor activity 14/1489 51/18639 0.274509803921569 3.43625804922372 3.13115486648101e-05 0.000850630405394007 GO:0005030 neurotrophin receptor activity 14/1489 51/18639 0.274509803921569 3.43625804922372 3.13115486648101e-05 0.000850630405394007 GO:0035401 histone H3Y41 kinase activity 23/1489 115/18639 0.2 2.503559435863 3.39283646192493e-05 0.000879824182512806 GO:0140801 histone H2AXY142 kinase activity 23/1489 115/18639 0.2 2.503559435863 3.39283646192493e-05 0.000879824182512806 GO:0031720 haptoglobin binding 6/1489 10/18639 0.6 7.51067830758899 4.07905236109169e-05 0.0010342663875568 GO:0001664 G protein-coupled receptor binding 44/1489 297/18639 0.148148148148148 1.85448847100963 4.9754269425147e-05 0.00118973735130865 GO:0005003 ephrin receptor activity 14/1489 53/18639 0.264150943396226 3.30658793415867 5.00503004932649e-05 0.00118973735130865 GO:0005005 transmembrane-ephrin receptor activity 14/1489 53/18639 0.264150943396226 3.30658793415867 5.00503004932649e-05 0.00118973735130865 GO:0004714 transmembrane receptor protein tyrosine kinase activity 15/1489 60/18639 0.25 3.12944929482874 5.47718474461469e-05 0.00127540159053171 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 9/1489 24/18639 0.375 4.69417394224312 5.60349703888748e-05 0.00127871802427412 GO:0004129 cytochrome-c oxidase activity 7/1489 15/18639 0.466666666666667 5.84163868368032 7.42401596197696e-05 0.00166094161031681 GO:0001540 amyloid-beta binding 18/1489 83/18639 0.216867469879518 2.71470300274301 7.88081929138021e-05 0.00172923361758939 GO:0019864 IgG binding 6/1489 11/18639 0.545454545454545 6.82788937053544 8.36541326639733e-05 0.0018009314220678 GO:0097110 scaffold protein binding 16/1489 70/18639 0.228571428571429 2.86121078384342 0.000100270983907375 0.00211868875256138 GO:0140375 immune receptor activity 27/1489 156/18639 0.173076923076923 2.16654181949682 0.000105579208549663 0.00219028867191211 GO:0004713 protein tyrosine kinase activity 25/1489 140/18639 0.178571428571429 2.23532092487767 0.000112161104219458 0.00228528249847146 GO:0019199 transmembrane receptor protein kinase activity 17/1489 78/18639 0.217948717948718 2.72823784677378 0.000115610242024153 0.00231423309034313 GO:0051219 phosphoprotein binding 19/1489 93/18639 0.204301075268817 2.55739942373102 0.000118157383409511 0.00232444093914228 GO:0016675 oxidoreductase activity, acting on a heme group of donors 7/1489 16/18639 0.4375 5.4765362659503 0.00012288462154065 0.00237646361318444 GO:0005109 frizzled binding 11/1489 38/18639 0.289473684210526 3.62357286769644 0.000129990463345034 0.00247198531127806 GO:0045309 protein phosphorylated amino acid binding 14/1489 59/18639 0.23728813559322 2.97032475441372 0.000175985808555208 0.00329180012395889 GO:0001618 virus receptor activity 17/1489 81/18639 0.209876543209877 2.62719200059697 0.000188355319029679 0.00346634546794942 GO:0030169 low-density lipoprotein particle binding 7/1489 17/18639 0.411764705882353 5.15438707383558 0.000194522035214994 0.00352301019333823 GO:0016500 protein-hormone receptor activity 15/1489 67/18639 0.223880597014925 2.80249190581679 0.000209453221177515 0.00373415820880538 GO:0140272 exogenous protein binding 17/1489 82/18639 0.207317073170732 2.59515307376042 0.000220191975401851 0.00381897764974549 GO:0046875 ephrin receptor binding 9/1489 28/18639 0.321428571428571 4.02357766477981 0.0002209049297837 0.00381897764974549 GO:0001784 phosphotyrosine residue binding 12/1489 47/18639 0.25531914893617 3.19603332237829 0.000242291364645404 0.00412618577702099 GO:0098632 cell-cell adhesion mediator activity 13/1489 55/18639 0.236363636363636 2.95875206056536 0.000309768505152237 0.0051977332996868 GO:1901981 phosphatidylinositol phosphate binding 29/1489 185/18639 0.156756756756757 1.96224928756829 0.000350992542196147 0.00580409406733049 GO:1990782 protein tyrosine kinase binding 21/1489 117/18639 0.179487179487179 2.24678410910782 0.000357358270400851 0.00582493980753386 GO:0033612 receptor serine/threonine kinase binding 9/1489 30/18639 0.3 3.75533915379449 0.000395466260203075 0.00635530989988322 GO:0005344 oxygen carrier activity 6/1489 14/18639 0.428571428571429 5.36477021970642 0.000440776016186654 0.00688938951327359 GO:0019763 immunoglobulin receptor activity 6/1489 14/18639 0.428571428571429 5.36477021970642 0.000440776016186654 0.00688938951327359 GO:0035173 histone kinase activity 47/1489 360/18639 0.130555555555556 1.63426796507723 0.000577390038294169 0.00890273018504929 GO:0035091 phosphatidylinositol binding 39/1489 284/18639 0.137323943661972 1.71899327462424 0.000619964106246291 0.0094317206030269 GO:0008013 beta-catenin binding 19/1489 106/18639 0.179245283018868 2.2437560981791 0.00067989641078188 0.0100222697781733 GO:0031386 protein tag activity 6/1489 15/18639 0.4 5.00711887172599 0.000685133253897912 0.0100222697781733 GO:0141047 molecular tag activity 6/1489 15/18639 0.4 5.00711887172599 0.000685133253897912 0.0100222697781733 GO:0015399 primary active transmembrane transporter activity 26/1489 166/18639 0.156626506024096 1.96061883531439 0.000700591016348725 0.0101186626538468 GO:0140311 protein sequestering activity 9/1489 33/18639 0.272727272727273 3.41394468526772 0.000856957204765292 0.0121781951183905 GO:0140996 histone H3 kinase activity 46/1489 357/18639 0.128851540616246 1.61293745167644 0.000869892863307784 0.0121781951183905 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 7/1489 21/18639 0.333333333333333 4.17259905977166 0.000875207712276971 0.0121781951183905 GO:0140297 DNA-binding transcription factor binding 59/1489 488/18639 0.120901639344262 1.51342219995816 0.000906395698578861 0.0124602107479335 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 10/1489 40/18639 0.25 3.12944929482874 0.000943385861214055 0.0128143246148242 GO:0005504 fatty acid binding 11/1489 47/18639 0.234042553191489 2.9296972121801 0.000966107977671862 0.0129685788532188 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 6/1489 16/18639 0.375 4.69417394224312 0.00102248243331227 0.0135657262373174 GO:0004601 peroxidase activity 12/1489 57/18639 0.210526315789474 2.63532572196105 0.00155897263738089 0.0202134974914955 GO:0016504 peptidase activator activity 12/1489 57/18639 0.210526315789474 2.63532572196105 0.00155897263738089 0.0202134974914955 GO:0030246 carbohydrate binding 37/1489 280/18639 0.132142857142857 1.65413748440948 0.00170044343365236 0.0218000669415432 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 44/1489 349/18639 0.126074498567335 1.57817500254974 0.00171973675000488 0.0218024403528396 GO:0003954 NADH dehydrogenase activity 10/1489 44/18639 0.227272727272727 2.84495390438977 0.00206099638689177 0.0255848664881017 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 6/1489 18/18639 0.333333333333333 4.17259905977166 0.00206293402007481 0.0255848664881017 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 12/1489 59/18639 0.203389830508475 2.54599264664033 0.00212783370250438 0.0261060027371774 GO:0030165 PDZ domain binding 15/1489 83/18639 0.180722891566265 2.26225250228584 0.00220667208232509 0.0267852430418397 GO:0141003 histone H2AX kinase activity 44/1489 354/18639 0.124293785310734 1.55588439516909 0.00226792236111521 0.0272389412003417 GO:0005035 death receptor activity 5/1489 13/18639 0.384615384615385 4.81453737665961 0.00241229998477297 0.0283756111610924 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 5/1489 13/18639 0.384615384615385 4.81453737665961 0.00241229998477297 0.0283756111610924 GO:0008301 DNA binding, bending 6/1489 19/18639 0.315789473684211 3.95298858294157 0.00281331402472389 0.0327550132878567 GO:0071813 lipoprotein particle binding 8/1489 32/18639 0.25 3.12944929482874 0.00301613704385615 0.0344141236703986 GO:0071814 protein-lipid complex binding 8/1489 32/18639 0.25 3.12944929482874 0.00301613704385615 0.0344141236703986 GO:0016209 antioxidant activity 15/1489 86/18639 0.174418604651163 2.18333671732238 0.00315526996367305 0.0356451785005044 GO:0019956 chemokine binding 8/1489 33/18639 0.242424242424242 3.03461749801575 0.00370707459236521 0.0414683540185167 GO:0004896 cytokine receptor activity 16/1489 96/18639 0.166666666666667 2.08629952988583 0.00374879091392531 0.0415278682795028 GO:0031406 carboxylic acid binding 26/1489 187/18639 0.13903743315508 1.74044238856786 0.00392403105808562 0.0430511484353431 GO:0004857 enzyme inhibitor activity 49/1489 416/18639 0.117788461538462 1.474452071602 0.00397365426697743 0.0431803763678214 GO:0051020 GTPase binding 39/1489 315/18639 0.123809523809524 1.54982250791519 0.00416015873646131 0.0447805765877581 GO:0008137 NADH dehydrogenase (ubiquinone) activity 9/1489 41/18639 0.219512195121951 2.7478091369228 0.00436366492676601 0.0461013118651854 GO:0042169 SH2 domain binding 9/1489 41/18639 0.219512195121951 2.7478091369228 0.00436366492676601 0.0461013118651854 GO:0043177 organic acid binding 26/1489 189/18639 0.137566137566138 1.72202500879465 0.00452836697545525 0.0474024469632518 GO:0001846 opsonin binding 6/1489 21/18639 0.285714285714286 3.57651347980428 0.00490072615579156 0.050561924408898 GO:0004953 icosanoid receptor activity 5/1489 15/18639 0.333333333333333 4.17259905977166 0.00491881999069911 0.050561924408898 GO:0005031 tumor necrosis factor receptor activity 4/1489 10/18639 0.4 5.00711887172599 0.0057558197985805 0.0586374141980389 GO:0031625 ubiquitin protein ligase binding 37/1489 302/18639 0.122516556291391 1.53363740276376 0.00609966411064717 0.0615904137190126 GO:0031683 G-protein beta/gamma-subunit complex binding 6/1489 22/18639 0.272727272727273 3.41394468526772 0.00629005218160575 0.0624082568627144 GO:0061133 endopeptidase activator activity 6/1489 22/18639 0.272727272727273 3.41394468526772 0.00629005218160575 0.0624082568627144 GO:0070411 I-SMAD binding 5/1489 16/18639 0.3125 3.91181161853593 0.00668988251678403 0.0658030685487119 GO:0016798 hydrolase activity, acting on glycosyl bonds 19/1489 130/18639 0.146153846153846 1.82952420313065 0.00741225142935962 0.0722852895803362 GO:0005516 calmodulin binding 27/1489 207/18639 0.130434782608696 1.63275615382369 0.00790614944197533 0.076448445027914 GO:0001851 complement component C3b binding 4/1489 11/18639 0.363636363636364 4.55192624702363 0.00847826240799903 0.0780136887703782 GO:0004954 prostanoid receptor activity 4/1489 11/18639 0.363636363636364 4.55192624702363 0.00847826240799903 0.0780136887703782 GO:0010854 adenylate cyclase regulator activity 4/1489 11/18639 0.363636363636364 4.55192624702363 0.00847826240799903 0.0780136887703782 GO:0034713 type I transforming growth factor beta receptor binding 4/1489 11/18639 0.363636363636364 4.55192624702363 0.00847826240799903 0.0780136887703782 GO:0050786 RAGE receptor binding 4/1489 11/18639 0.363636363636364 4.55192624702363 0.00847826240799903 0.0780136887703782 GO:1990948 ubiquitin ligase inhibitor activity 4/1489 11/18639 0.363636363636364 4.55192624702363 0.00847826240799903 0.0780136887703782 GO:0036041 long-chain fatty acid binding 5/1489 17/18639 0.294117647058824 3.6817050527397 0.00886312640048122 0.0809026177835925 GO:0017147 Wnt-protein binding 7/1489 31/18639 0.225806451612903 2.82659936307112 0.00979344123851935 0.0886850512154808 GO:0044389 ubiquitin-like protein ligase binding 38/1489 322/18639 0.118012422360248 1.47725556774525 0.00998329116657312 0.0896924033154325 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 8/1489 39/18639 0.205128205128205 2.56775326755179 0.0107265410167401 0.0956170570320345 GO:0140313 molecular sequestering activity 10/1489 55/18639 0.181818181818182 2.27596312351181 0.0109302881476026 0.0966779750109657 GO:0000400 four-way junction DNA binding 5/1489 18/18639 0.277777777777778 3.47716588314305 0.0114785850083299 0.0992201931401846 GO:0030228 lipoprotein particle receptor activity 5/1489 18/18639 0.277777777777778 3.47716588314305 0.0114785850083299 0.0992201931401846 GO:0035615 clathrin adaptor activity 5/1489 18/18639 0.277777777777778 3.47716588314305 0.0114785850083299 0.0992201931401846 GO:0043425 bHLH transcription factor binding 7/1489 32/18639 0.21875 2.73826813297515 0.011691086413025 0.100297215017004 GO:0034452 dynactin binding 4/1489 12/18639 0.333333333333333 4.17259905977166 0.0119232053043505 0.101525203375104 GO:0001848 complement binding 6/1489 25/18639 0.24 3.00427132303559 0.0121529266941992 0.102714735985788 GO:0019887 protein kinase regulator activity 31/1489 255/18639 0.12156862745098 1.52177142179908 0.0125880232296476 0.10560981253697 GO:0019207 kinase regulator activity 34/1489 287/18639 0.118466898954704 1.48294461357738 0.0134661400452661 0.111663957035525 GO:0061134 peptidase regulator activity 28/1489 226/18639 0.123893805309735 1.55087752664079 0.0135053690367243 0.111663957035525 GO:0033218 amide binding 30/1489 247/18639 0.121457489878543 1.5203802242083 0.0140930133595247 0.115407477016468 GO:0035591 signaling adaptor activity 18/1489 129/18639 0.13953488372093 1.7466693738579 0.0142072556909924 0.115407477016468 GO:0022804 active transmembrane transporter activity 50/1489 457/18639 0.109409190371991 1.36956205462965 0.0143721658677038 0.115407477016468 GO:0001530 lipopolysaccharide binding 8/1489 41/18639 0.195121951219512 2.44249701059804 0.0144638643412401 0.115407477016468 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 8/1489 41/18639 0.195121951219512 2.44249701059804 0.0144638643412401 0.115407477016468 GO:0030506 ankyrin binding 5/1489 19/18639 0.263157894736842 3.29415715245131 0.014573324645332 0.115473357085582 GO:0019865 immunoglobulin binding 6/1489 26/18639 0.230769230769231 2.88872242599576 0.0147553926351883 0.116109675839654 GO:0017154 semaphorin receptor activity 4/1489 13/18639 0.307692307692308 3.85162990132769 0.0161502743352738 0.124503647268245 GO:0035673 oligopeptide transmembrane transporter activity 4/1489 13/18639 0.307692307692308 3.85162990132769 0.0161502743352738 0.124503647268245 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 4/1489 13/18639 0.307692307692308 3.85162990132769 0.0161502743352738 0.124503647268245 GO:0019825 oxygen binding 7/1489 34/18639 0.205882352941176 2.57719353691779 0.0162585832103142 0.124503647268245 GO:0015252 proton channel activity 6/1489 27/18639 0.222222222222222 2.78173270651444 0.0177207708547064 0.134795996968133 GO:0001614 purinergic nucleotide receptor activity 5/1489 20/18639 0.25 3.12944929482874 0.0181809068507516 0.136476412609918 GO:0016502 nucleotide receptor activity 5/1489 20/18639 0.25 3.12944929482874 0.0181809068507516 0.136476412609918 GO:0005539 glycosaminoglycan binding 29/1489 242/18639 0.119834710743802 1.50006660413279 0.0184272268591511 0.137421345400597 GO:0008081 phosphoric diester hydrolase activity 13/1489 87/18639 0.149425287356322 1.8704754405873 0.0203567642559229 0.150825116987065 GO:0005125 cytokine activity 28/1489 234/18639 0.11965811965812 1.49785607273854 0.0206434529594095 0.15196245049475 GO:0030159 signaling receptor complex adaptor activity 9/1489 52/18639 0.173076923076923 2.16654181949682 0.020855401587235 0.152186060723082 GO:0045499 chemorepellent activity 6/1489 28/18639 0.214285714285714 2.68238510985321 0.0210701178427135 0.152186060723082 GO:0005545 1-phosphatidylinositol binding 4/1489 14/18639 0.285714285714286 3.57651347980428 0.0212073476380106 0.152186060723082 GO:0019992 diacylglycerol binding 4/1489 14/18639 0.285714285714286 3.57651347980428 0.0212073476380106 0.152186060723082 GO:0016651 oxidoreductase activity, acting on NAD(P)H 13/1489 88/18639 0.147727272727273 1.84922003785335 0.02219867285172 0.156960153037504 GO:0009931 calcium-dependent protein serine/threonine kinase activity 5/1489 21/18639 0.238095238095238 2.9804278998369 0.0223309633179266 0.156960153037504 GO:0140312 cargo adaptor activity 5/1489 21/18639 0.238095238095238 2.9804278998369 0.0223309633179266 0.156960153037504 GO:0033293 monocarboxylic acid binding 12/1489 79/18639 0.151898734177215 1.90143754622506 0.0224228790053577 0.156960153037504 GO:0044325 transmembrane transporter binding 18/1489 136/18639 0.132352941176471 1.65676727373286 0.0232887151037307 0.162026975203395 GO:0004725 protein tyrosine phosphatase activity 14/1489 98/18639 0.142857142857143 1.78825673990214 0.02359274080858 0.163147377349029 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 13/1489 89/18639 0.146067415730337 1.82844228461904 0.0241617191451847 0.165080967333268 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 13/1489 89/18639 0.146067415730337 1.82844228461904 0.0241617191451847 0.165080967333268 GO:0004715 non-membrane spanning protein tyrosine kinase activity 8/1489 45/18639 0.177777777777778 2.22538616521155 0.0246289732828151 0.166603952042739 GO:0005496 steroid binding 15/1489 108/18639 0.138888888888889 1.73858294157152 0.0246840380610334 0.166603952042739 GO:0003785 actin monomer binding 6/1489 29/18639 0.206896551724138 2.58988907158241 0.0248226747127657 0.166603952042739 GO:0043394 proteoglycan binding 7/1489 37/18639 0.189189189189189 2.36823189878932 0.0252771466169622 0.168662130350607 GO:0042277 peptide binding 29/1489 249/18639 0.116465863453815 1.45789605702865 0.0259639283661453 0.169157605756086 GO:0003925 G protein activity 9/1489 54/18639 0.166666666666667 2.08629952988583 0.0261562059740719 0.169157605756086 GO:0140793 histone H2AXY142 phosphatase activity 13/1489 90/18639 0.144444444444444 1.80812625923439 0.0262501552182066 0.169157605756086 GO:0033691 sialic acid binding 5/1489 22/18639 0.227272727272727 2.84495390438977 0.027048878358021 0.169157605756086 GO:0140517 protein-RNA adaptor activity 5/1489 22/18639 0.227272727272727 2.84495390438977 0.027048878358021 0.169157605756086 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 4/1489 15/18639 0.266666666666667 3.33807924781733 0.0271304486006693 0.169157605756086 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 4/1489 15/18639 0.266666666666667 3.33807924781733 0.0271304486006693 0.169157605756086 GO:0005041 low-density lipoprotein particle receptor activity 4/1489 15/18639 0.266666666666667 3.33807924781733 0.0271304486006693 0.169157605756086 GO:0015929 hexosaminidase activity 4/1489 15/18639 0.266666666666667 3.33807924781733 0.0271304486006693 0.169157605756086 GO:0031005 filamin binding 4/1489 15/18639 0.266666666666667 3.33807924781733 0.0271304486006693 0.169157605756086 GO:0050700 CARD domain binding 4/1489 15/18639 0.266666666666667 3.33807924781733 0.0271304486006693 0.169157605756086 GO:0055105 ubiquitin-protein transferase inhibitor activity 4/1489 15/18639 0.266666666666667 3.33807924781733 0.0271304486006693 0.169157605756086 GO:0004180 carboxypeptidase activity 8/1489 46/18639 0.173913043478261 2.17700820509826 0.0277967525894984 0.172370079916401 GO:0019212 phosphatase inhibitor activity 9/1489 56/18639 0.160714285714286 2.01178883238991 0.0323436118698334 0.197420895894086 GO:0005158 insulin receptor binding 5/1489 23/18639 0.217391304347826 2.72126025637282 0.0323555718949992 0.197420895894086 GO:0031681 G-protein beta-subunit binding 5/1489 23/18639 0.217391304347826 2.72126025637282 0.0323555718949992 0.197420895894086 GO:0000217 DNA secondary structure binding 7/1489 39/18639 0.179487179487179 2.24678410910782 0.0328978502954005 0.199661953122617 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 4/1489 16/18639 0.25 3.12944929482874 0.033943970628631 0.202712866841199 GO:0005159 insulin-like growth factor receptor binding 4/1489 16/18639 0.25 3.12944929482874 0.033943970628631 0.202712866841199 GO:0005324 long-chain fatty acid transmembrane transporter activity 4/1489 16/18639 0.25 3.12944929482874 0.033943970628631 0.202712866841199 GO:0020037 heme binding 18/1489 142/18639 0.126760563380282 1.58676302273007 0.0341111923168363 0.202712866841199 GO:0048027 mRNA 5'-UTR binding 5/1489 24/18639 0.208333333333333 2.60787441235729 0.0382673746864201 0.217746931636121 GO:0050431 transforming growth factor beta binding 5/1489 24/18639 0.208333333333333 2.60787441235729 0.0382673746864201 0.217746931636121 GO:0035254 glutamate receptor binding 8/1489 49/18639 0.163265306122449 2.04372198845959 0.0389608950728407 0.217746931636121 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 9/1489 58/18639 0.155172413793103 1.94241680368681 0.0394769702511271 0.217746931636121 GO:0004955 prostaglandin receptor activity 3/1489 10/18639 0.3 3.75533915379449 0.0398852837089828 0.217746931636121 GO:0005381 iron ion transmembrane transporter activity 3/1489 10/18639 0.3 3.75533915379449 0.0398852837089828 0.217746931636121 GO:0008239 dipeptidyl-peptidase activity 3/1489 10/18639 0.3 3.75533915379449 0.0398852837089828 0.217746931636121 GO:0015658 branched-chain amino acid transmembrane transporter activity 3/1489 10/18639 0.3 3.75533915379449 0.0398852837089828 0.217746931636121 GO:0016175 superoxide-generating NAD(P)H oxidase activity 3/1489 10/18639 0.3 3.75533915379449 0.0398852837089828 0.217746931636121 GO:0016303 1-phosphatidylinositol-3-kinase activity 3/1489 10/18639 0.3 3.75533915379449 0.0398852837089828 0.217746931636121 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 3/1489 10/18639 0.3 3.75533915379449 0.0398852837089828 0.217746931636121 GO:0031434 mitogen-activated protein kinase kinase binding 3/1489 10/18639 0.3 3.75533915379449 0.0398852837089828 0.217746931636121 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 3/1489 10/18639 0.3 3.75533915379449 0.0398852837089828 0.217746931636121 GO:0071723 lipopeptide binding 3/1489 10/18639 0.3 3.75533915379449 0.0398852837089828 0.217746931636121 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 3/1489 10/18639 0.3 3.75533915379449 0.0398852837089828 0.217746931636121 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 3/1489 10/18639 0.3 3.75533915379449 0.0398852837089828 0.217746931636121 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 3/1489 10/18639 0.3 3.75533915379449 0.0398852837089828 0.217746931636121 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 4/1489 17/18639 0.235294117647059 2.94536404219176 0.0416611534680617 0.223170779845345 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 4/1489 17/18639 0.235294117647059 2.94536404219176 0.0416611534680617 0.223170779845345 GO:0015278 intracellularly gated calcium channel activity 4/1489 17/18639 0.235294117647059 2.94536404219176 0.0416611534680617 0.223170779845345 GO:0019198 transmembrane receptor protein phosphatase activity 4/1489 17/18639 0.235294117647059 2.94536404219176 0.0416611534680617 0.223170779845345 GO:0140789 histone phosphatase activity 17/1489 136/18639 0.125 1.56472464741437 0.0433172578894677 0.228276934497588 GO:0001786 phosphatidylserine binding 9/1489 59/18639 0.152542372881356 1.90949448498025 0.0434146317142651 0.228276934497588 GO:0004879 nuclear receptor activity 9/1489 59/18639 0.152542372881356 1.90949448498025 0.0434146317142651 0.228276934497588 GO:0070888 E-box binding 9/1489 59/18639 0.152542372881356 1.90949448498025 0.0434146317142651 0.228276934497588 GO:0030296 protein tyrosine kinase activator activity 6/1489 33/18639 0.181818181818182 2.27596312351181 0.0441767531963984 0.230162901356578 GO:0140416 transcription regulator inhibitor activity 6/1489 33/18639 0.181818181818182 2.27596312351181 0.0441767531963984 0.230162901356578 GO:0003707 nuclear steroid receptor activity 5/1489 25/18639 0.2 2.503559435863 0.0447959866844753 0.231277017226183 GO:0005537 D-mannose binding 5/1489 25/18639 0.2 2.503559435863 0.0447959866844753 0.231277017226183 GO:0031267 small GTPase binding 31/1489 283/18639 0.109540636042403 1.37120746487196 0.0453027620590834 0.232839871664028 GO:0019208 phosphatase regulator activity 15/1489 117/18639 0.128205128205128 1.60484579221987 0.0459005369147219 0.234460900021711 GO:0042826 histone deacetylase binding 16/1489 127/18639 0.125984251968504 1.57704531392945 0.0460291337465936 0.234460900021711 GO:0005201 extracellular matrix structural constituent 20/1489 168/18639 0.119047619047619 1.49021394991845 0.0470565338283507 0.238628911547325 GO:0098531 ligand-modulated transcription factor activity 9/1489 60/18639 0.15 1.87766957689725 0.047607107969737 0.240352699971106 GO:0046332 SMAD binding 11/1489 79/18639 0.139240506329114 1.74298441737297 0.0488766464971396 0.24567512622571 GO:0031690 adrenergic receptor binding 4/1489 18/18639 0.222222222222222 2.78173270651444 0.0502847444565565 0.248723155911847 GO:0098641 cadherin binding involved in cell-cell adhesion 4/1489 18/18639 0.222222222222222 2.78173270651444 0.0502847444565565 0.248723155911847 GO:0005126 cytokine receptor binding 30/1489 275/18639 0.109090909090909 1.36557787410709 0.050466643285133 0.248723155911847 GO:0008271 secondary active sulfate transmembrane transporter activity 3/1489 11/18639 0.272727272727273 3.41394468526772 0.0516629166968517 0.248723155911847 GO:0019206 nucleoside kinase activity 3/1489 11/18639 0.272727272727273 3.41394468526772 0.0516629166968517 0.248723155911847 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 3/1489 11/18639 0.272727272727273 3.41394468526772 0.0516629166968517 0.248723155911847 GO:0034056 estrogen response element binding 3/1489 11/18639 0.272727272727273 3.41394468526772 0.0516629166968517 0.248723155911847 GO:0099528 G protein-coupled neurotransmitter receptor activity 3/1489 11/18639 0.272727272727273 3.41394468526772 0.0516629166968517 0.248723155911847 GO:0140031 phosphorylation-dependent protein binding 3/1489 11/18639 0.272727272727273 3.41394468526772 0.0516629166968517 0.248723155911847 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 3/1489 11/18639 0.272727272727273 3.41394468526772 0.0516629166968517 0.248723155911847 GO:0005160 transforming growth factor beta receptor binding 5/1489 26/18639 0.192307692307692 2.4072686883298 0.0519485090771626 0.249047264105221 GO:0048306 calcium-dependent protein binding 11/1489 80/18639 0.1375 1.72119711215581 0.0527580775154124 0.250916048996558 GO:0005080 protein kinase C binding 8/1489 52/18639 0.153846153846154 1.92581495066384 0.0527781347582594 0.250916048996558 GO:0019210 kinase inhibitor activity 12/1489 90/18639 0.133333333333333 1.66903962390866 0.0541048521673517 0.256156167315138 GO:0005154 epidermal growth factor receptor binding 6/1489 35/18639 0.171428571428571 2.14590808788257 0.0566140644677477 0.266928295692976 GO:0072341 modified amino acid binding 12/1489 91/18639 0.131868131868132 1.65069852914044 0.0579990363949566 0.271226431378656 GO:0004864 protein phosphatase inhibitor activity 8/1489 53/18639 0.150943396226415 1.88947881951924 0.0580010948785206 0.271226431378656 GO:1902936 phosphatidylinositol bisphosphate binding 14/1489 111/18639 0.126126126126126 1.57882126585955 0.0587498819201635 0.273606592942476 GO:0023026 MHC class II protein complex binding 5/1489 27/18639 0.185185185185185 2.31811058876203 0.0597275404913573 0.274058988324603 GO:0035255 ionotropic glutamate receptor binding 5/1489 27/18639 0.185185185185185 2.31811058876203 0.0597275404913573 0.274058988324603 GO:0046906 tetrapyrrole binding 18/1489 152/18639 0.118421052631579 1.48237071860309 0.0597304327952066 0.274058988324603 GO:0015245 fatty acid transmembrane transporter activity 4/1489 19/18639 0.210526315789474 2.63532572196105 0.0598077897395497 0.274058988324603 GO:0061135 endopeptidase regulator activity 21/1489 184/18639 0.114130434782609 1.42866163459573 0.0618748595342316 0.282396858914233 GO:0008238 exopeptidase activity 13/1489 102/18639 0.127450980392157 1.59540552285387 0.0624680004467686 0.283968081712203 GO:0004875 complement receptor activity 3/1489 12/18639 0.25 3.12944929482874 0.0649094871610188 0.284852787887394 GO:0005095 GTPase inhibitor activity 3/1489 12/18639 0.25 3.12944929482874 0.0649094871610188 0.284852787887394 GO:0005165 neurotrophin receptor binding 3/1489 12/18639 0.25 3.12944929482874 0.0649094871610188 0.284852787887394 GO:0010853 cyclase activator activity 3/1489 12/18639 0.25 3.12944929482874 0.0649094871610188 0.284852787887394 GO:0045295 gamma-catenin binding 3/1489 12/18639 0.25 3.12944929482874 0.0649094871610188 0.284852787887394 GO:0070008 serine-type exopeptidase activity 3/1489 12/18639 0.25 3.12944929482874 0.0649094871610188 0.284852787887394 GO:0097677 STAT family protein binding 3/1489 12/18639 0.25 3.12944929482874 0.0649094871610188 0.284852787887394 GO:0141221 histone deacetylase activity, hydrolytic mechanism 3/1489 12/18639 0.25 3.12944929482874 0.0649094871610188 0.284852787887394 GO:1990247 N6-methyladenosine-containing RNA reader activity 3/1489 12/18639 0.25 3.12944929482874 0.0649094871610188 0.284852787887394 GO:0005216 monoatomic ion channel activity 45/1489 448/18639 0.100446428571429 1.25736802024369 0.0656898761100652 0.287172983301089 GO:0097718 disordered domain specific binding 5/1489 28/18639 0.178571428571429 2.23532092487767 0.0681313280236712 0.296709333110721 GO:0010851 cyclase regulator activity 4/1489 20/18639 0.2 2.503559435863 0.0702145104617493 0.302785164434214 GO:0016505 peptidase activator activity involved in apoptotic process 4/1489 20/18639 0.2 2.503559435863 0.0702145104617493 0.302785164434214 GO:0004860 protein kinase inhibitor activity 11/1489 84/18639 0.130952380952381 1.63923534491029 0.0703225842025125 0.302785164434214 GO:0004629 phospholipase C activity 5/1489 29/18639 0.172413793103448 2.15824089298534 0.0771539641301098 0.328480123404684 GO:0043236 laminin binding 5/1489 29/18639 0.172413793103448 2.15824089298534 0.0771539641301098 0.328480123404684 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 5/1489 29/18639 0.172413793103448 2.15824089298534 0.0771539641301098 0.328480123404684 GO:0042887 amide transmembrane transporter activity 6/1489 38/18639 0.157894736842105 1.97649429147079 0.0788321018233975 0.334377056433073 GO:0008035 high-density lipoprotein particle binding 3/1489 13/18639 0.230769230769231 2.88872242599576 0.0795372510087423 0.334878241332011 GO:0031994 insulin-like growth factor I binding 3/1489 13/18639 0.230769230769231 2.88872242599576 0.0795372510087423 0.334878241332011 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 11/1489 86/18639 0.127906976744186 1.60111359270308 0.0803582818435502 0.337091174939304 GO:0008373 sialyltransferase activity 4/1489 21/18639 0.19047619047619 2.38434231986952 0.0814812274367664 0.340549745440844 GO:0050840 extracellular matrix binding 9/1489 67/18639 0.134328358208955 1.68149514349007 0.084408647898673 0.351497325738635 GO:0140693 molecular condensate scaffold activity 7/1489 48/18639 0.145833333333333 1.8255120886501 0.085216850260211 0.353572458716003 GO:0030295 protein kinase activator activity 16/1489 139/18639 0.115107913669065 1.44089751704345 0.0885038328260868 0.365879975560018 GO:0004197 cysteine-type endopeptidase activity 11/1489 88/18639 0.125 1.56472464741437 0.0912426975902421 0.375840859026954 GO:0008093 cytoskeletal anchor activity 4/1489 22/18639 0.181818181818182 2.27596312351181 0.0935773050098209 0.379453689150693 GO:0030021 extracellular matrix structural constituent conferring compression resistance 4/1489 22/18639 0.181818181818182 2.27596312351181 0.0935773050098209 0.379453689150693 GO:0004620 phospholipase activity 13/1489 109/18639 0.119266055045872 1.49294828744124 0.0943571271471463 0.379453689150693 GO:0005161 platelet-derived growth factor receptor binding 3/1489 14/18639 0.214285714285714 2.68238510985321 0.0954454064734873 0.379453689150693 GO:0008474 palmitoyl-(protein) hydrolase activity 3/1489 14/18639 0.214285714285714 2.68238510985321 0.0954454064734873 0.379453689150693 GO:0032036 myosin heavy chain binding 3/1489 14/18639 0.214285714285714 2.68238510985321 0.0954454064734873 0.379453689150693 GO:0034236 protein kinase A catalytic subunit binding 3/1489 14/18639 0.214285714285714 2.68238510985321 0.0954454064734873 0.379453689150693 GO:0042043 neurexin family protein binding 3/1489 14/18639 0.214285714285714 2.68238510985321 0.0954454064734873 0.379453689150693 GO:0098599 palmitoyl hydrolase activity 3/1489 14/18639 0.214285714285714 2.68238510985321 0.0954454064734873 0.379453689150693 GO:0098847 sequence-specific single stranded DNA binding 3/1489 14/18639 0.214285714285714 2.68238510985321 0.0954454064734873 0.379453689150693 GO:0030331 nuclear estrogen receptor binding 6/1489 40/18639 0.15 1.87766957689725 0.0959998401418063 0.380332700006253 GO:0005164 tumor necrosis factor receptor binding 5/1489 31/18639 0.161290322580645 2.0189995450508 0.0970128138356998 0.383015988188697 GO:0042578 phosphoric ester hydrolase activity 36/1489 363/18639 0.0991735537190083 1.24143443100644 0.104291605116195 0.410333522198547 GO:0004721 phosphoprotein phosphatase activity 19/1489 175/18639 0.108571428571429 1.35907512232563 0.105966851733044 0.410398005911087 GO:0004602 glutathione peroxidase activity 4/1489 23/18639 0.173913043478261 2.17700820509826 0.106466090928731 0.410398005911087 GO:0016493 C-C chemokine receptor activity 4/1489 23/18639 0.173913043478261 2.17700820509826 0.106466090928731 0.410398005911087 GO:0016849 phosphorus-oxygen lyase activity 4/1489 23/18639 0.173913043478261 2.17700820509826 0.106466090928731 0.410398005911087 GO:0043274 phospholipase binding 4/1489 23/18639 0.173913043478261 2.17700820509826 0.106466090928731 0.410398005911087 GO:0140103 catalytic activity, acting on a glycoprotein 4/1489 23/18639 0.173913043478261 2.17700820509826 0.106466090928731 0.410398005911087 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 11/1489 91/18639 0.120879120879121 1.51314031837873 0.109161615254897 0.419371727292384 GO:0005200 structural constituent of cytoskeleton 13/1489 112/18639 0.116071428571429 1.45295860117049 0.110614582234923 0.419575328495001 GO:0030971 receptor tyrosine kinase binding 10/1489 81/18639 0.123456790123457 1.54540705917469 0.110629165455466 0.419575328495001 GO:0004089 carbonate dehydratase activity 3/1489 15/18639 0.2 2.503559435863 0.112524145941692 0.419575328495001 GO:0005523 tropomyosin binding 3/1489 15/18639 0.2 2.503559435863 0.112524145941692 0.419575328495001 GO:0015116 sulfate transmembrane transporter activity 3/1489 15/18639 0.2 2.503559435863 0.112524145941692 0.419575328495001 GO:0016846 carbon-sulfur lyase activity 3/1489 15/18639 0.2 2.503559435863 0.112524145941692 0.419575328495001 GO:0034483 heparan sulfate sulfotransferase activity 3/1489 15/18639 0.2 2.503559435863 0.112524145941692 0.419575328495001 GO:0141050 histone H3K deacetylase activity 3/1489 15/18639 0.2 2.503559435863 0.112524145941692 0.419575328495001 GO:0141051 histone H4K deacetylase activity 3/1489 15/18639 0.2 2.503559435863 0.112524145941692 0.419575328495001 GO:0042056 chemoattractant activity 6/1489 42/18639 0.142857142857143 1.78825673990214 0.114989826857548 0.427372613825612 GO:0043178 alcohol binding 11/1489 92/18639 0.119565217391304 1.49669314100505 0.115555967068498 0.428082332549207 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 4/1489 24/18639 0.166666666666667 2.08629952988583 0.120105834177193 0.435050021575166 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 4/1489 24/18639 0.166666666666667 2.08629952988583 0.120105834177193 0.435050021575166 GO:0005540 hyaluronic acid binding 4/1489 24/18639 0.166666666666667 2.08629952988583 0.120105834177193 0.435050021575166 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 4/1489 24/18639 0.166666666666667 2.08629952988583 0.120105834177193 0.435050021575166 GO:0019957 C-C chemokine binding 4/1489 24/18639 0.166666666666667 2.08629952988583 0.120105834177193 0.435050021575166 GO:0030215 semaphorin receptor binding 4/1489 24/18639 0.166666666666667 2.08629952988583 0.120105834177193 0.435050021575166 GO:0030552 cAMP binding 4/1489 24/18639 0.166666666666667 2.08629952988583 0.120105834177193 0.435050021575166 GO:0008200 ion channel inhibitor activity 6/1489 43/18639 0.13953488372093 1.7466693738579 0.125141256301343 0.450429569210827 GO:0008375 acetylglucosaminyltransferase activity 6/1489 43/18639 0.13953488372093 1.7466693738579 0.125141256301343 0.450429569210827 GO:0043539 protein serine/threonine kinase activator activity 9/1489 73/18639 0.123287671232877 1.54329006320322 0.126540940359827 0.454035260850826 GO:0005246 calcium channel regulator activity 7/1489 53/18639 0.132075471698113 1.65329396707934 0.127457071546723 0.455888773149877 GO:0015562 efflux transmembrane transporter activity 3/1489 16/18639 0.1875 2.34708697112156 0.130658032552398 0.462983897957411 GO:0031435 mitogen-activated protein kinase kinase kinase binding 3/1489 16/18639 0.1875 2.34708697112156 0.130658032552398 0.462983897957411 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 3/1489 16/18639 0.1875 2.34708697112156 0.130658032552398 0.462983897957411 GO:0019209 kinase activator activity 16/1489 148/18639 0.108108108108108 1.35327537073675 0.132942731430615 0.469621227747158 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 4/1489 25/18639 0.16 2.0028475486904 0.134450567032949 0.470705896287288 GO:0017025 TBP-class protein binding 4/1489 25/18639 0.16 2.0028475486904 0.134450567032949 0.470705896287288 GO:0048029 monosaccharide binding 9/1489 74/18639 0.121621621621622 1.52243479207885 0.134487398939225 0.470705896287288 GO:0016248 channel inhibitor activity 6/1489 44/18639 0.136363636363636 1.70697234263386 0.135712319573412 0.472096819003849 GO:0019205 nucleobase-containing compound kinase activity 6/1489 44/18639 0.136363636363636 1.70697234263386 0.135712319573412 0.472096819003849 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 7/1489 54/18639 0.12962962962963 1.62267741213342 0.136976734224111 0.475046971883617 GO:0003725 double-stranded RNA binding 9/1489 75/18639 0.12 1.5021356615178 0.142686786935003 0.482600429600019 GO:0070851 growth factor receptor binding 15/1489 139/18639 0.107913669064748 1.35084142222823 0.143682210535045 0.482600429600019 GO:0008201 heparin binding 18/1489 172/18639 0.104651162790698 1.31000203039343 0.144557110479315 0.482600429600019 GO:0005261 monoatomic cation channel activity 33/1489 341/18639 0.0967741935483871 1.21139972703048 0.14499151353443 0.482600429600019 GO:0019888 protein phosphatase regulator activity 12/1489 107/18639 0.11214953271028 1.40386510422224 0.14585494282188 0.482600429600019 GO:0008009 chemokine activity 6/1489 45/18639 0.133333333333333 1.66903962390866 0.146687491459033 0.482600429600019 GO:0141110 transporter inhibitor activity 6/1489 45/18639 0.133333333333333 1.66903962390866 0.146687491459033 0.482600429600019 GO:0001637 G protein-coupled chemoattractant receptor activity 4/1489 26/18639 0.153846153846154 1.92581495066384 0.149450941206728 0.482600429600019 GO:0004112 cyclic-nucleotide phosphodiesterase activity 4/1489 26/18639 0.153846153846154 1.92581495066384 0.149450941206728 0.482600429600019 GO:0004435 phosphatidylinositol phospholipase C activity 4/1489 26/18639 0.153846153846154 1.92581495066384 0.149450941206728 0.482600429600019 GO:0004950 chemokine receptor activity 4/1489 26/18639 0.153846153846154 1.92581495066384 0.149450941206728 0.482600429600019 GO:0005112 Notch binding 4/1489 26/18639 0.153846153846154 1.92581495066384 0.149450941206728 0.482600429600019 GO:0008066 glutamate receptor activity 4/1489 26/18639 0.153846153846154 1.92581495066384 0.149450941206728 0.482600429600019 GO:0008198 ferrous iron binding 4/1489 26/18639 0.153846153846154 1.92581495066384 0.149450941206728 0.482600429600019 GO:0030247 polysaccharide binding 4/1489 26/18639 0.153846153846154 1.92581495066384 0.149450941206728 0.482600429600019 GO:0030507 spectrin binding 4/1489 26/18639 0.153846153846154 1.92581495066384 0.149450941206728 0.482600429600019 GO:0043548 phosphatidylinositol 3-kinase binding 4/1489 26/18639 0.153846153846154 1.92581495066384 0.149450941206728 0.482600429600019 GO:0008429 phosphatidylethanolamine binding 3/1489 17/18639 0.176470588235294 2.20902303164382 0.149728792356185 0.482600429600019 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 3/1489 17/18639 0.176470588235294 2.20902303164382 0.149728792356185 0.482600429600019 GO:0015347 sodium-independent organic anion transmembrane transporter activity 3/1489 17/18639 0.176470588235294 2.20902303164382 0.149728792356185 0.482600429600019 GO:0016805 dipeptidase activity 3/1489 17/18639 0.176470588235294 2.20902303164382 0.149728792356185 0.482600429600019 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 3/1489 17/18639 0.176470588235294 2.20902303164382 0.149728792356185 0.482600429600019 GO:0038191 neuropilin binding 3/1489 17/18639 0.176470588235294 2.20902303164382 0.149728792356185 0.482600429600019 GO:0046965 nuclear retinoid X receptor binding 3/1489 17/18639 0.176470588235294 2.20902303164382 0.149728792356185 0.482600429600019 GO:1990226 histone methyltransferase binding 3/1489 17/18639 0.176470588235294 2.20902303164382 0.149728792356185 0.482600429600019 GO:0008235 metalloexopeptidase activity 8/1489 66/18639 0.121212121212121 1.51730874900788 0.154494221664178 0.496557484278385 GO:0170055 lipid transmembrane transporter activity 7/1489 56/18639 0.125 1.56472464741437 0.157012593691362 0.503234183713045 GO:0030276 clathrin binding 6/1489 46/18639 0.130434782608696 1.63275615382369 0.158049795799236 0.505139543436775 GO:0046982 protein heterodimerization activity 35/1489 369/18639 0.0948509485094851 1.18732493570738 0.164481541716194 0.523132687313177 GO:0004364 glutathione transferase activity 4/1489 27/18639 0.148148148148148 1.85448847100963 0.165055010896357 0.523132687313177 GO:0008266 poly(U) RNA binding 4/1489 27/18639 0.148148148148148 1.85448847100963 0.165055010896357 0.523132687313177 GO:0015103 inorganic anion transmembrane transporter activity 17/1489 165/18639 0.103030303030303 1.28971243665669 0.1679158477769 0.530615209905853 GO:0015108 chloride transmembrane transporter activity 13/1489 121/18639 0.107438016528926 1.34488730025698 0.168505442592821 0.530615209905853 GO:0004970 glutamate-gated receptor activity 3/1489 18/18639 0.166666666666667 2.08629952988583 0.16961760193611 0.530615209905853 GO:0017075 syntaxin-1 binding 3/1489 18/18639 0.166666666666667 2.08629952988583 0.16961760193611 0.530615209905853 GO:0023023 MHC protein complex binding 5/1489 37/18639 0.135135135135135 1.69159421342094 0.169741061889252 0.530615209905853 GO:0046943 carboxylic acid transmembrane transporter activity 19/1489 188/18639 0.101063829787234 1.26509652344141 0.171806721512277 0.535605107228163 GO:0030145 manganese ion binding 8/1489 68/18639 0.117647058823529 1.47268202109588 0.173762950948713 0.540227594093955 GO:0016829 lyase activity 20/1489 200/18639 0.1 1.2517797179315 0.176095638312045 0.545992182918595 GO:0005342 organic acid transmembrane transporter activity 19/1489 189/18639 0.100529100529101 1.25840289104225 0.177612735160677 0.549203606553745 GO:0051019 mitogen-activated protein kinase binding 4/1489 28/18639 0.142857142857143 1.78825673990214 0.181208958041805 0.551192376196713 GO:0051087 protein-folding chaperone binding 14/1489 134/18639 0.104477611940299 1.30782955604783 0.18287100526576 0.551192376196713 GO:0019902 phosphatase binding 19/1489 190/18639 0.1 1.2517797179315 0.183518621187624 0.551192376196713 GO:0001216 DNA-binding transcription activator activity 45/1489 491/18639 0.0916496945010183 1.14725228730993 0.185372350671644 0.551192376196713 GO:0016247 channel regulator activity 17/1489 168/18639 0.101190476190476 1.26668185743068 0.186645908270517 0.551192376196713 GO:0003680 minor groove of adenine-thymine-rich DNA binding 2/1489 10/18639 0.2 2.503559435863 0.18743439260677 0.551192376196713 GO:0004935 adrenergic receptor activity 2/1489 10/18639 0.2 2.503559435863 0.18743439260677 0.551192376196713 GO:0008190 eukaryotic initiation factor 4E binding 2/1489 10/18639 0.2 2.503559435863 0.18743439260677 0.551192376196713 GO:0008641 ubiquitin-like modifier activating enzyme activity 2/1489 10/18639 0.2 2.503559435863 0.18743439260677 0.551192376196713 GO:0015203 polyamine transmembrane transporter activity 2/1489 10/18639 0.2 2.503559435863 0.18743439260677 0.551192376196713 GO:0015279 store-operated calcium channel activity 2/1489 10/18639 0.2 2.503559435863 0.18743439260677 0.551192376196713 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/1489 10/18639 0.2 2.503559435863 0.18743439260677 0.551192376196713 GO:0019911 structural constituent of myelin sheath 2/1489 10/18639 0.2 2.503559435863 0.18743439260677 0.551192376196713 GO:0031996 thioesterase binding 2/1489 10/18639 0.2 2.503559435863 0.18743439260677 0.551192376196713 GO:0043422 protein kinase B binding 2/1489 10/18639 0.2 2.503559435863 0.18743439260677 0.551192376196713 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 2/1489 10/18639 0.2 2.503559435863 0.18743439260677 0.551192376196713 GO:0050815 phosphoserine residue binding 2/1489 10/18639 0.2 2.503559435863 0.18743439260677 0.551192376196713 GO:0098505 G-rich strand telomeric DNA binding 2/1489 10/18639 0.2 2.503559435863 0.18743439260677 0.551192376196713 GO:1905394 retromer complex binding 2/1489 10/18639 0.2 2.503559435863 0.18743439260677 0.551192376196713 GO:0005520 insulin-like growth factor binding 3/1489 19/18639 0.157894736842105 1.97649429147079 0.190206941722965 0.555054016639139 GO:0043395 heparan sulfate proteoglycan binding 3/1489 19/18639 0.157894736842105 1.97649429147079 0.190206941722965 0.555054016639139 GO:0050145 nucleoside monophosphate kinase activity 3/1489 19/18639 0.157894736842105 1.97649429147079 0.190206941722965 0.555054016639139 GO:0008028 monocarboxylic acid transmembrane transporter activity 8/1489 70/18639 0.114285714285714 1.43060539192171 0.194041028689526 0.560083219352472 GO:0060590 ATPase regulator activity 6/1489 49/18639 0.122448979591837 1.53279149134469 0.194271127396632 0.560083219352472 GO:0033192 calmodulin-dependent protein phosphatase activity 9/1489 81/18639 0.111111111111111 1.39086635325722 0.196839063067784 0.560083219352472 GO:0140791 histone H2AXS140 phosphatase activity 9/1489 81/18639 0.111111111111111 1.39086635325722 0.196839063067784 0.560083219352472 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 9/1489 81/18639 0.111111111111111 1.39086635325722 0.196839063067784 0.560083219352472 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 9/1489 81/18639 0.111111111111111 1.39086635325722 0.196839063067784 0.560083219352472 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 9/1489 81/18639 0.111111111111111 1.39086635325722 0.196839063067784 0.560083219352472 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 9/1489 81/18639 0.111111111111111 1.39086635325722 0.196839063067784 0.560083219352472 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 9/1489 81/18639 0.111111111111111 1.39086635325722 0.196839063067784 0.560083219352472 GO:1990439 MAP kinase serine/threonine phosphatase activity 9/1489 81/18639 0.111111111111111 1.39086635325722 0.196839063067784 0.560083219352472 GO:0002020 protease binding 14/1489 136/18639 0.102941176470588 1.28859676845889 0.197386207891171 0.560187843211462 GO:0099604 ligand-gated calcium channel activity 4/1489 29/18639 0.137931034482759 1.72659271438827 0.197857757067677 0.560187843211462 GO:0141108 transporter regulator activity 17/1489 170/18639 0.1 1.2517797179315 0.199681929886805 0.563953173269417 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 44/1489 484/18639 0.0909090909090909 1.13798156175591 0.203559993435649 0.572092751076641 GO:0016922 nuclear receptor binding 14/1489 137/18639 0.102189781021898 1.27919095263073 0.204838316524519 0.572092751076641 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 9/1489 82/18639 0.109756097560976 1.3739045684614 0.206620048621264 0.572092751076641 GO:0033549 MAP kinase phosphatase activity 9/1489 82/18639 0.109756097560976 1.3739045684614 0.206620048621264 0.572092751076641 GO:0032813 tumor necrosis factor receptor superfamily binding 6/1489 50/18639 0.12 1.5021356615178 0.206988434463537 0.572092751076641 GO:0099106 ion channel regulator activity 16/1489 160/18639 0.1 1.2517797179315 0.208508962211808 0.572092751076641 GO:0008509 monoatomic anion transmembrane transporter activity 15/1489 149/18639 0.100671140939597 1.26018092409211 0.210541676672869 0.572092751076641 GO:1901681 sulfur compound binding 26/1489 275/18639 0.0945454545454545 1.18350082422614 0.210960669867897 0.572092751076641 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 3/1489 20/18639 0.15 1.87766957689725 0.211382076651415 0.572092751076641 GO:0071855 neuropeptide receptor binding 5/1489 40/18639 0.125 1.56472464741437 0.212207478418864 0.572092751076641 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 7/1489 61/18639 0.114754098360656 1.43646852877385 0.212323399806679 0.572092751076641 GO:0001968 fibronectin binding 4/1489 30/18639 0.133333333333333 1.66903962390866 0.214945778016346 0.572092751076641 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 4/1489 30/18639 0.133333333333333 1.66903962390866 0.214945778016346 0.572092751076641 GO:0008187 poly-pyrimidine tract binding 4/1489 30/18639 0.133333333333333 1.66903962390866 0.214945778016346 0.572092751076641 GO:0031624 ubiquitin conjugating enzyme binding 4/1489 30/18639 0.133333333333333 1.66903962390866 0.214945778016346 0.572092751076641 GO:0005518 collagen binding 8/1489 72/18639 0.111111111111111 1.39086635325722 0.215241714078358 0.572092751076641 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 9/1489 83/18639 0.108433734939759 1.3573515013715 0.216594030177241 0.572092751076641 GO:0003953 NAD+ nucleosidase activity 2/1489 11/18639 0.181818181818182 2.27596312351181 0.217605831697863 0.572092751076641 GO:0005114 type II transforming growth factor beta receptor binding 2/1489 11/18639 0.181818181818182 2.27596312351181 0.217605831697863 0.572092751076641 GO:0005225 volume-sensitive anion channel activity 2/1489 11/18639 0.181818181818182 2.27596312351181 0.217605831697863 0.572092751076641 GO:0008046 axon guidance receptor activity 2/1489 11/18639 0.181818181818182 2.27596312351181 0.217605831697863 0.572092751076641 GO:0015173 aromatic amino acid transmembrane transporter activity 2/1489 11/18639 0.181818181818182 2.27596312351181 0.217605831697863 0.572092751076641 GO:0016176 superoxide-generating NADPH oxidase activator activity 2/1489 11/18639 0.181818181818182 2.27596312351181 0.217605831697863 0.572092751076641 GO:0032404 mismatch repair complex binding 2/1489 11/18639 0.181818181818182 2.27596312351181 0.217605831697863 0.572092751076641 GO:0035252 UDP-xylosyltransferase activity 2/1489 11/18639 0.181818181818182 2.27596312351181 0.217605831697863 0.572092751076641 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 2/1489 11/18639 0.181818181818182 2.27596312351181 0.217605831697863 0.572092751076641 GO:0042285 xylosyltransferase activity 2/1489 11/18639 0.181818181818182 2.27596312351181 0.217605831697863 0.572092751076641 GO:0048185 activin binding 2/1489 11/18639 0.181818181818182 2.27596312351181 0.217605831697863 0.572092751076641 GO:0050998 nitric-oxide synthase binding 2/1489 11/18639 0.181818181818182 2.27596312351181 0.217605831697863 0.572092751076641 GO:0070697 activin receptor binding 2/1489 11/18639 0.181818181818182 2.27596312351181 0.217605831697863 0.572092751076641 GO:0005272 sodium channel activity 6/1489 51/18639 0.117647058823529 1.47268202109588 0.219991480152833 0.577035123803178 GO:0008083 growth factor activity 16/1489 162/18639 0.0987654320987654 1.23632564733975 0.222726192721861 0.582868316274412 GO:0017018 myosin phosphatase activity 9/1489 84/18639 0.107142857142857 1.3411925549266 0.226751538153917 0.59069293386671 GO:0051117 ATPase binding 9/1489 84/18639 0.107142857142857 1.3411925549266 0.226751538153917 0.59069293386671 GO:0005452 solute:inorganic anion antiporter activity 4/1489 31/18639 0.129032258064516 1.61519963604064 0.232417328265331 0.602924628008126 GO:0009975 cyclase activity 3/1489 21/18639 0.142857142857143 1.78825673990214 0.23303221818719 0.602924628008126 GO:0072542 protein phosphatase activator activity 3/1489 21/18639 0.142857142857143 1.78825673990214 0.23303221818719 0.602924628008126 GO:0005507 copper ion binding 7/1489 63/18639 0.111111111111111 1.39086635325722 0.236229427130003 0.605649753039652 GO:1901682 sulfur compound transmembrane transporter activity 7/1489 63/18639 0.111111111111111 1.39086635325722 0.236229427130003 0.605649753039652 GO:0016298 lipase activity 13/1489 130/18639 0.1 1.2517797179315 0.238663674105303 0.605649753039652 GO:0035198 miRNA binding 5/1489 42/18639 0.119047619047619 1.49021394991845 0.242204202441269 0.605649753039652 GO:0051879 Hsp90 protein binding 5/1489 42/18639 0.119047619047619 1.49021394991845 0.242204202441269 0.605649753039652 GO:0008514 organic anion transmembrane transporter activity 25/1489 269/18639 0.0929368029739777 1.16336405012221 0.242405523066321 0.605649753039652 GO:0017046 peptide hormone binding 6/1489 53/18639 0.113207547169811 1.41710911463943 0.246764185856855 0.605649753039652 GO:0140296 general transcription initiation factor binding 6/1489 53/18639 0.113207547169811 1.41710911463943 0.246764185856855 0.605649753039652 GO:0005262 calcium channel activity 13/1489 131/18639 0.099236641221374 1.24222414756561 0.2470964789176 0.605649753039652 GO:0004300 enoyl-CoA hydratase activity 2/1489 12/18639 0.166666666666667 2.08629952988583 0.248145100605232 0.605649753039652 GO:0004859 phospholipase inhibitor activity 2/1489 12/18639 0.166666666666667 2.08629952988583 0.248145100605232 0.605649753039652 GO:0005025 transforming growth factor beta receptor activity, type I 2/1489 12/18639 0.166666666666667 2.08629952988583 0.248145100605232 0.605649753039652 GO:0005026 transforming growth factor beta receptor activity, type II 2/1489 12/18639 0.166666666666667 2.08629952988583 0.248145100605232 0.605649753039652 GO:0008179 adenylate cyclase binding 2/1489 12/18639 0.166666666666667 2.08629952988583 0.248145100605232 0.605649753039652 GO:0008504 monoamine transmembrane transporter activity 2/1489 12/18639 0.166666666666667 2.08629952988583 0.248145100605232 0.605649753039652 GO:0015132 prostaglandin transmembrane transporter activity 2/1489 12/18639 0.166666666666667 2.08629952988583 0.248145100605232 0.605649753039652 GO:0016208 AMP binding 2/1489 12/18639 0.166666666666667 2.08629952988583 0.248145100605232 0.605649753039652 GO:0016361 activin receptor activity, type I 2/1489 12/18639 0.166666666666667 2.08629952988583 0.248145100605232 0.605649753039652 GO:0016362 activin receptor activity, type II 2/1489 12/18639 0.166666666666667 2.08629952988583 0.248145100605232 0.605649753039652 GO:0017002 activin receptor activity 2/1489 12/18639 0.166666666666667 2.08629952988583 0.248145100605232 0.605649753039652 GO:0043047 single-stranded telomeric DNA binding 2/1489 12/18639 0.166666666666667 2.08629952988583 0.248145100605232 0.605649753039652 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 2/1489 12/18639 0.166666666666667 2.08629952988583 0.248145100605232 0.605649753039652 GO:0070410 co-SMAD binding 2/1489 12/18639 0.166666666666667 2.08629952988583 0.248145100605232 0.605649753039652 GO:0097371 MDM2/MDM4 family protein binding 2/1489 12/18639 0.166666666666667 2.08629952988583 0.248145100605232 0.605649753039652 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 2/1489 12/18639 0.166666666666667 2.08629952988583 0.248145100605232 0.605649753039652 GO:1990459 transferrin receptor binding 2/1489 12/18639 0.166666666666667 2.08629952988583 0.248145100605232 0.605649753039652 GO:0005506 iron ion binding 15/1489 154/18639 0.0974025974025974 1.21926595902419 0.248417251904082 0.605649753039652 GO:0035403 histone H3T6 kinase activity 23/1489 247/18639 0.0931174089068826 1.16562483855969 0.250633362468043 0.609749822123746 GO:0004407 histone deacetylase activity 3/1489 22/18639 0.136363636363636 1.70697234263386 0.255051415004669 0.613952878734868 GO:0005243 gap junction channel activity 3/1489 22/18639 0.136363636363636 1.70697234263386 0.255051415004669 0.613952878734868 GO:0008970 phospholipase A1 activity 3/1489 22/18639 0.136363636363636 1.70697234263386 0.255051415004669 0.613952878734868 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 3/1489 22/18639 0.136363636363636 1.70697234263386 0.255051415004669 0.613952878734868 GO:0033558 protein lysine deacetylase activity 3/1489 22/18639 0.136363636363636 1.70697234263386 0.255051415004669 0.613952878734868 GO:0048156 tau protein binding 5/1489 43/18639 0.116279069767442 1.45555781154825 0.257607221670206 0.618799663001485 GO:0003697 single-stranded DNA binding 12/1489 121/18639 0.0991735537190083 1.24143443100644 0.259196711947568 0.619200773649565 GO:0017022 myosin binding 8/1489 76/18639 0.105263157894737 1.31766286098052 0.260026389147263 0.619200773649565 GO:0019903 protein phosphatase binding 14/1489 144/18639 0.0972222222222222 1.21700805910007 0.260277325216889 0.619200773649565 GO:0015485 cholesterol binding 6/1489 54/18639 0.111111111111111 1.39086635325722 0.260487617310948 0.619200773649565 GO:0051287 NAD binding 6/1489 54/18639 0.111111111111111 1.39086635325722 0.260487617310948 0.619200773649565 GO:0071889 14-3-3 protein binding 4/1489 33/18639 0.121212121212121 1.51730874900788 0.268290763689518 0.636423620311309 GO:0030414 peptidase inhibitor activity 16/1489 169/18639 0.0946745562130177 1.18511689271621 0.275510538855459 0.647885997125617 GO:0017134 fibroblast growth factor binding 3/1489 23/18639 0.130434782608696 1.63275615382369 0.27733921361606 0.647885997125617 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 3/1489 23/18639 0.130434782608696 1.63275615382369 0.27733921361606 0.647885997125617 GO:0005542 folic acid binding 2/1489 13/18639 0.153846153846154 1.92581495066384 0.278801073259139 0.647885997125617 GO:0019855 calcium channel inhibitor activity 2/1489 13/18639 0.153846153846154 1.92581495066384 0.278801073259139 0.647885997125617 GO:0031432 titin binding 2/1489 13/18639 0.153846153846154 1.92581495066384 0.278801073259139 0.647885997125617 GO:0039706 co-receptor binding 2/1489 13/18639 0.153846153846154 1.92581495066384 0.278801073259139 0.647885997125617 GO:0070123 transforming growth factor beta receptor activity, type III 2/1489 13/18639 0.153846153846154 1.92581495066384 0.278801073259139 0.647885997125617 GO:0071714 icosanoid transmembrane transporter activity 2/1489 13/18639 0.153846153846154 1.92581495066384 0.278801073259139 0.647885997125617 GO:0089720 caspase binding 2/1489 13/18639 0.153846153846154 1.92581495066384 0.278801073259139 0.647885997125617 GO:0003727 single-stranded RNA binding 9/1489 89/18639 0.101123595505618 1.26584465858241 0.279940148160746 0.649210790754901 GO:0015085 calcium ion transmembrane transporter activity 14/1489 147/18639 0.0952380952380952 1.19217115993476 0.285555295049152 0.660592888313065 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 7/1489 67/18639 0.104477611940299 1.30782955604783 0.286377063573319 0.660592888313065 GO:0015035 protein-disulfide reductase activity 4/1489 34/18639 0.117647058823529 1.47268202109588 0.286584995368069 0.660592888313065 GO:0030170 pyridoxal phosphate binding 6/1489 56/18639 0.107142857142857 1.3411925549266 0.288491628082951 0.663600970435736 GO:0046915 transition metal ion transmembrane transporter activity 5/1489 45/18639 0.111111111111111 1.39086635325722 0.289053183441333 0.663600970435736 GO:0106310 protein serine kinase activity 32/1489 361/18639 0.0886426592797784 1.10961083029939 0.294334991148831 0.672343162963332 GO:0015171 amino acid transmembrane transporter activity 10/1489 102/18639 0.0980392156862745 1.2272350175799 0.296972757395705 0.672343162963332 GO:0032934 sterol binding 7/1489 68/18639 0.102941176470588 1.28859676845889 0.299299994530242 0.672343162963332 GO:0001091 RNA polymerase II general transcription initiation factor binding 3/1489 24/18639 0.125 1.56472464741437 0.29980112496447 0.672343162963332 GO:0004622 lysophospholipase activity 3/1489 24/18639 0.125 1.56472464741437 0.29980112496447 0.672343162963332 GO:0042625 ATPase-coupled ion transmembrane transporter activity 3/1489 24/18639 0.125 1.56472464741437 0.29980112496447 0.672343162963332 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 3/1489 24/18639 0.125 1.56472464741437 0.29980112496447 0.672343162963332 GO:0046961 proton-transporting ATPase activity, rotational mechanism 3/1489 24/18639 0.125 1.56472464741437 0.29980112496447 0.672343162963332 GO:0070300 phosphatidic acid binding 3/1489 24/18639 0.125 1.56472464741437 0.29980112496447 0.672343162963332 GO:0070840 dynein complex binding 3/1489 24/18639 0.125 1.56472464741437 0.29980112496447 0.672343162963332 GO:0070279 vitamin B6 binding 6/1489 57/18639 0.105263157894737 1.31766286098052 0.302725329904643 0.672343162963332 GO:0030291 protein serine/threonine kinase inhibitor activity 5/1489 46/18639 0.108695652173913 1.36063012818641 0.305029206324515 0.672343162963332 GO:0004866 endopeptidase inhibitor activity 15/1489 161/18639 0.093167701863354 1.16625439558835 0.305334590563793 0.672343162963332 GO:0004065 arylsulfatase activity 2/1489 14/18639 0.142857142857143 1.78825673990214 0.309360351056748 0.672343162963332 GO:0008191 metalloendopeptidase inhibitor activity 2/1489 14/18639 0.142857142857143 1.78825673990214 0.309360351056748 0.672343162963332 GO:0008331 high voltage-gated calcium channel activity 2/1489 14/18639 0.142857142857143 1.78825673990214 0.309360351056748 0.672343162963332 GO:0016530 metallochaperone activity 2/1489 14/18639 0.142857142857143 1.78825673990214 0.309360351056748 0.672343162963332 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 2/1489 14/18639 0.142857142857143 1.78825673990214 0.309360351056748 0.672343162963332 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 2/1489 14/18639 0.142857142857143 1.78825673990214 0.309360351056748 0.672343162963332 GO:0030983 mismatched DNA binding 2/1489 14/18639 0.142857142857143 1.78825673990214 0.309360351056748 0.672343162963332 GO:0031404 chloride ion binding 2/1489 14/18639 0.142857142857143 1.78825673990214 0.309360351056748 0.672343162963332 GO:0042813 Wnt receptor activity 2/1489 14/18639 0.142857142857143 1.78825673990214 0.309360351056748 0.672343162963332 GO:0044548 S100 protein binding 2/1489 14/18639 0.142857142857143 1.78825673990214 0.309360351056748 0.672343162963332 GO:0061665 SUMO ligase activity 2/1489 14/18639 0.142857142857143 1.78825673990214 0.309360351056748 0.672343162963332 GO:0071933 Arp2/3 complex binding 2/1489 14/18639 0.142857142857143 1.78825673990214 0.309360351056748 0.672343162963332 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 2/1489 14/18639 0.142857142857143 1.78825673990214 0.309360351056748 0.672343162963332 GO:0098821 BMP receptor activity 2/1489 14/18639 0.142857142857143 1.78825673990214 0.309360351056748 0.672343162963332 GO:1990825 sequence-specific mRNA binding 2/1489 14/18639 0.142857142857143 1.78825673990214 0.309360351056748 0.672343162963332 GO:0061980 regulatory RNA binding 6/1489 58/18639 0.103448275862069 1.2949445357912 0.317082459886303 0.687815754240061 GO:0004709 MAP kinase kinase kinase activity 3/1489 25/18639 0.12 1.5021356615178 0.322348928318768 0.69135362257841 GO:0015271 outward rectifier potassium channel activity 3/1489 25/18639 0.12 1.5021356615178 0.322348928318768 0.69135362257841 GO:0015662 P-type ion transporter activity 3/1489 25/18639 0.12 1.5021356615178 0.322348928318768 0.69135362257841 GO:0019211 phosphatase activator activity 3/1489 25/18639 0.12 1.5021356615178 0.322348928318768 0.69135362257841 GO:0042974 nuclear retinoic acid receptor binding 3/1489 25/18639 0.12 1.5021356615178 0.322348928318768 0.69135362257841 GO:0140358 P-type transmembrane transporter activity 3/1489 25/18639 0.12 1.5021356615178 0.322348928318768 0.69135362257841 GO:0044390 ubiquitin-like protein conjugating enzyme binding 4/1489 36/18639 0.111111111111111 1.39086635325722 0.323630267016653 0.691502124842699 GO:0055106 ubiquitin-protein transferase regulator activity 4/1489 36/18639 0.111111111111111 1.39086635325722 0.323630267016653 0.691502124842699 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 12/1489 128/18639 0.09375 1.17354348556078 0.324887945103026 0.692891860490752 GO:0015459 potassium channel regulator activity 6/1489 59/18639 0.101694915254237 1.27299632332017 0.331540052587239 0.705254225943114 GO:0042562 hormone binding 9/1489 94/18639 0.0957446808510638 1.19851249589186 0.336155049815939 0.705254225943114 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 5/1489 48/18639 0.104166666666667 1.30393720617864 0.337324217341708 0.705254225943114 GO:0032266 phosphatidylinositol-3-phosphate binding 5/1489 48/18639 0.104166666666667 1.30393720617864 0.337324217341708 0.705254225943114 GO:0140299 molecular sensor activity 7/1489 71/18639 0.0985915492957746 1.23414901767894 0.338716542810699 0.705254225943114 GO:0000149 SNARE binding 10/1489 106/18639 0.0943396226415094 1.18092426219953 0.339621402169732 0.705254225943114 GO:0017081 chloride channel regulator activity 2/1489 15/18639 0.133333333333333 1.66903962390866 0.339642844151372 0.705254225943114 GO:0048531 beta-1,3-galactosyltransferase activity 2/1489 15/18639 0.133333333333333 1.66903962390866 0.339642844151372 0.705254225943114 GO:0050780 dopamine receptor binding 2/1489 15/18639 0.133333333333333 1.66903962390866 0.339642844151372 0.705254225943114 GO:0120283 protein serine/threonine kinase binding 2/1489 15/18639 0.133333333333333 1.66903962390866 0.339642844151372 0.705254225943114 GO:0016791 phosphatase activity 24/1489 273/18639 0.0879120879120879 1.10046568609362 0.342268716928343 0.705254225943114 GO:0019213 deacetylase activity 4/1489 37/18639 0.108108108108108 1.35327537073675 0.342283504001793 0.705254225943114 GO:0022829 wide pore channel activity 4/1489 37/18639 0.108108108108108 1.35327537073675 0.342283504001793 0.705254225943114 GO:0030551 cyclic nucleotide binding 4/1489 37/18639 0.108108108108108 1.35327537073675 0.342283504001793 0.705254225943114 GO:0042805 actinin binding 4/1489 37/18639 0.108108108108108 1.35327537073675 0.342283504001793 0.705254225943114 GO:0005254 chloride channel activity 8/1489 83/18639 0.0963855421686747 1.20653466788578 0.343861226676355 0.705254225943114 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 3/1489 26/18639 0.115384615384615 1.44436121299788 0.344900839681208 0.705254225943114 GO:0008143 poly(A) binding 3/1489 26/18639 0.115384615384615 1.44436121299788 0.344900839681208 0.705254225943114 GO:0050681 nuclear androgen receptor binding 3/1489 26/18639 0.115384615384615 1.44436121299788 0.344900839681208 0.705254225943114 GO:0050750 low-density lipoprotein particle receptor binding 3/1489 26/18639 0.115384615384615 1.44436121299788 0.344900839681208 0.705254225943114 GO:0052742 phosphatidylinositol kinase activity 3/1489 26/18639 0.115384615384615 1.44436121299788 0.344900839681208 0.705254225943114 GO:0070006 metalloaminopeptidase activity 3/1489 26/18639 0.115384615384615 1.44436121299788 0.344900839681208 0.705254225943114 GO:0070412 R-SMAD binding 3/1489 26/18639 0.115384615384615 1.44436121299788 0.344900839681208 0.705254225943114 GO:0004867 serine-type endopeptidase inhibitor activity 9/1489 95/18639 0.0947368421052632 1.18589657488247 0.347640667046557 0.709584975134385 GO:0042379 chemokine receptor binding 7/1489 72/18639 0.0972222222222222 1.21700805910007 0.352013832058797 0.717228182819799 GO:0031072 heat shock protein binding 12/1489 131/18639 0.0916030534351145 1.14666844390672 0.354145212921677 0.720284648740879 GO:0016836 hydro-lyase activity 6/1489 61/18639 0.0983606557377049 1.23125873894901 0.360666639511609 0.727663949114173 GO:0000146 microfilament motor activity 4/1489 38/18639 0.105263157894737 1.31766286098052 0.360962134266978 0.727663949114173 GO:0005501 retinoid binding 4/1489 38/18639 0.105263157894737 1.31766286098052 0.360962134266978 0.727663949114173 GO:0019840 isoprenoid binding 4/1489 38/18639 0.105263157894737 1.31766286098052 0.360962134266978 0.727663949114173 GO:0043531 ADP binding 4/1489 38/18639 0.105263157894737 1.31766286098052 0.360962134266978 0.727663949114173 GO:0005179 hormone activity 12/1489 132/18639 0.0909090909090909 1.13798156175591 0.363995801795804 0.729406590773959 GO:0003714 transcription corepressor activity 18/1489 204/18639 0.0882352941176471 1.10451151582191 0.365284825447908 0.729406590773959 GO:0001671 ATPase activator activity 3/1489 27/18639 0.111111111111111 1.39086635325722 0.367381568279314 0.729406590773959 GO:0005024 transforming growth factor beta receptor activity 2/1489 16/18639 0.125 1.56472464741437 0.36949781723694 0.729406590773959 GO:0005521 lamin binding 2/1489 16/18639 0.125 1.56472464741437 0.36949781723694 0.729406590773959 GO:0015923 mannosidase activity 2/1489 16/18639 0.125 1.56472464741437 0.36949781723694 0.729406590773959 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 2/1489 16/18639 0.125 1.56472464741437 0.36949781723694 0.729406590773959 GO:0017070 U6 snRNA binding 2/1489 16/18639 0.125 1.56472464741437 0.36949781723694 0.729406590773959 GO:0019841 retinol binding 2/1489 16/18639 0.125 1.56472464741437 0.36949781723694 0.729406590773959 GO:0022841 potassium ion leak channel activity 2/1489 16/18639 0.125 1.56472464741437 0.36949781723694 0.729406590773959 GO:0055102 lipase inhibitor activity 2/1489 16/18639 0.125 1.56472464741437 0.36949781723694 0.729406590773959 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 2/1489 16/18639 0.125 1.56472464741437 0.36949781723694 0.729406590773959 GO:0015179 L-amino acid transmembrane transporter activity 6/1489 62/18639 0.0967741935483871 1.21139972703048 0.375291816464894 0.739564702221838 GO:0000287 magnesium ion binding 20/1489 230/18639 0.0869565217391304 1.08850410254913 0.379667190066106 0.74394041171212 GO:0030544 Hsp70 protein binding 5/1489 51/18639 0.0980392156862745 1.2272350175799 0.386159180877749 0.74394041171212 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 21/1489 243/18639 0.0864197530864197 1.08178494142228 0.386201083868446 0.74394041171212 GO:0019789 SUMO transferase activity 3/1489 28/18639 0.107142857142857 1.3411925549266 0.389722281507815 0.74394041171212 GO:0046625 sphingolipid binding 3/1489 28/18639 0.107142857142857 1.3411925549266 0.389722281507815 0.74394041171212 GO:0050698 proteoglycan sulfotransferase activity 3/1489 28/18639 0.107142857142857 1.3411925549266 0.389722281507815 0.74394041171212 GO:0051393 alpha-actinin binding 3/1489 28/18639 0.107142857142857 1.3411925549266 0.389722281507815 0.74394041171212 GO:0051537 2 iron, 2 sulfur cluster binding 3/1489 28/18639 0.107142857142857 1.3411925549266 0.389722281507815 0.74394041171212 GO:0051959 dynein light intermediate chain binding 3/1489 28/18639 0.107142857142857 1.3411925549266 0.389722281507815 0.74394041171212 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 3/1489 28/18639 0.107142857142857 1.3411925549266 0.389722281507815 0.74394041171212 GO:0015297 antiporter activity 12/1489 135/18639 0.0888888888888889 1.11269308260578 0.393748210244206 0.74394041171212 GO:0004177 aminopeptidase activity 4/1489 40/18639 0.1 1.2517797179315 0.398224475155848 0.74394041171212 GO:0015036 disulfide oxidoreductase activity 4/1489 40/18639 0.1 1.2517797179315 0.398224475155848 0.74394041171212 GO:0004659 prenyltransferase activity 2/1489 17/18639 0.117647058823529 1.47268202109588 0.398800353887707 0.74394041171212 GO:0008484 sulfuric ester hydrolase activity 2/1489 17/18639 0.117647058823529 1.47268202109588 0.398800353887707 0.74394041171212 GO:0008569 minus-end-directed microtubule motor activity 2/1489 17/18639 0.117647058823529 1.47268202109588 0.398800353887707 0.74394041171212 GO:0045125 bioactive lipid receptor activity 2/1489 17/18639 0.117647058823529 1.47268202109588 0.398800353887707 0.74394041171212 GO:0048038 quinone binding 2/1489 17/18639 0.117647058823529 1.47268202109588 0.398800353887707 0.74394041171212 GO:0070403 NAD+ binding 2/1489 17/18639 0.117647058823529 1.47268202109588 0.398800353887707 0.74394041171212 GO:0004676 3-phosphoinositide-dependent protein kinase activity 21/1489 245/18639 0.0857142857142857 1.07295404394128 0.400984533920205 0.74394041171212 GO:0004711 ribosomal protein S6 kinase activity 21/1489 245/18639 0.0857142857142857 1.07295404394128 0.400984533920205 0.74394041171212 GO:0035175 histone H3S10 kinase activity 21/1489 245/18639 0.0857142857142857 1.07295404394128 0.400984533920205 0.74394041171212 GO:0035979 histone H2AXS139 kinase activity 21/1489 245/18639 0.0857142857142857 1.07295404394128 0.400984533920205 0.74394041171212 GO:0044022 histone H3S28 kinase activity 21/1489 245/18639 0.0857142857142857 1.07295404394128 0.400984533920205 0.74394041171212 GO:0044023 histone H4S1 kinase activity 21/1489 245/18639 0.0857142857142857 1.07295404394128 0.400984533920205 0.74394041171212 GO:0044024 histone H2AS1 kinase activity 21/1489 245/18639 0.0857142857142857 1.07295404394128 0.400984533920205 0.74394041171212 GO:0044025 histone H2BS14 kinase activity 21/1489 245/18639 0.0857142857142857 1.07295404394128 0.400984533920205 0.74394041171212 GO:0072354 histone H3T3 kinase activity 21/1489 245/18639 0.0857142857142857 1.07295404394128 0.400984533920205 0.74394041171212 GO:0072371 histone H2AS121 kinase activity 21/1489 245/18639 0.0857142857142857 1.07295404394128 0.400984533920205 0.74394041171212 GO:0072518 Rho-dependent protein serine/threonine kinase activity 21/1489 245/18639 0.0857142857142857 1.07295404394128 0.400984533920205 0.74394041171212 GO:0140823 histone H2BS36 kinase activity 21/1489 245/18639 0.0857142857142857 1.07295404394128 0.400984533920205 0.74394041171212 GO:0140855 histone H3S57 kinase activity 21/1489 245/18639 0.0857142857142857 1.07295404394128 0.400984533920205 0.74394041171212 GO:0140995 histone H2A kinase activity 21/1489 245/18639 0.0857142857142857 1.07295404394128 0.400984533920205 0.74394041171212 GO:0140997 histone H4 kinase activity 21/1489 245/18639 0.0857142857142857 1.07295404394128 0.400984533920205 0.74394041171212 GO:0140998 histone H2B kinase activity 21/1489 245/18639 0.0857142857142857 1.07295404394128 0.400984533920205 0.74394041171212 GO:1990244 histone H2AT120 kinase activity 21/1489 245/18639 0.0857142857142857 1.07295404394128 0.400984533920205 0.74394041171212 GO:0004677 DNA-dependent protein kinase activity 21/1489 246/18639 0.0853658536585366 1.06859244213664 0.40839965467148 0.755241500778216 GO:0140857 histone H3T45 kinase activity 21/1489 246/18639 0.0853658536585366 1.06859244213664 0.40839965467148 0.755241500778216 GO:0035402 histone H3T11 kinase activity 21/1489 247/18639 0.0850202429149798 1.06426615694581 0.415826784270123 0.766452383583627 GO:0008227 G protein-coupled amine receptor activity 4/1489 41/18639 0.0975609756097561 1.22124850529902 0.416728782316545 0.766452383583627 GO:0015175 neutral L-amino acid transmembrane transporter activity 4/1489 41/18639 0.0975609756097561 1.22124850529902 0.416728782316545 0.766452383583627 GO:0005544 calcium-dependent phospholipid binding 5/1489 53/18639 0.0943396226415094 1.18092426219953 0.418639992464518 0.766452383583627 GO:0008146 sulfotransferase activity 5/1489 53/18639 0.0943396226415094 1.18092426219953 0.418639992464518 0.766452383583627 GO:0016860 intramolecular oxidoreductase activity 5/1489 53/18639 0.0943396226415094 1.18092426219953 0.418639992464518 0.766452383583627 GO:0019843 rRNA binding 6/1489 65/18639 0.0923076923076923 1.15548897039831 0.41916414316931 0.766452383583627 GO:0004679 AMP-activated protein kinase activity 21/1489 248/18639 0.0846774193548387 1.05997476115167 0.423263242735084 0.768060462650346 GO:0004674 protein serine/threonine kinase activity 36/1489 433/18639 0.0831408775981524 1.04074064308392 0.426084865238815 0.768060462650346 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/1489 18/18639 0.111111111111111 1.39086635325722 0.427448197881656 0.768060462650346 GO:0004706 JUN kinase kinase kinase activity 2/1489 18/18639 0.111111111111111 1.39086635325722 0.427448197881656 0.768060462650346 GO:0008525 phosphatidylcholine transporter activity 2/1489 18/18639 0.111111111111111 1.39086635325722 0.427448197881656 0.768060462650346 GO:0015172 acidic amino acid transmembrane transporter activity 2/1489 18/18639 0.111111111111111 1.39086635325722 0.427448197881656 0.768060462650346 GO:0015280 ligand-gated sodium channel activity 2/1489 18/18639 0.111111111111111 1.39086635325722 0.427448197881656 0.768060462650346 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 2/1489 18/18639 0.111111111111111 1.39086635325722 0.427448197881656 0.768060462650346 GO:0032393 MHC class I receptor activity 2/1489 18/18639 0.111111111111111 1.39086635325722 0.427448197881656 0.768060462650346 GO:0034185 apolipoprotein binding 2/1489 18/18639 0.111111111111111 1.39086635325722 0.427448197881656 0.768060462650346 GO:0070064 proline-rich region binding 2/1489 18/18639 0.111111111111111 1.39086635325722 0.427448197881656 0.768060462650346 GO:0001965 G-protein alpha-subunit binding 3/1489 30/18639 0.1 1.2517797179315 0.433739908960731 0.775700997059865 GO:0031210 phosphatidylcholine binding 3/1489 30/18639 0.1 1.2517797179315 0.433739908960731 0.775700997059865 GO:0070566 adenylyltransferase activity 3/1489 30/18639 0.1 1.2517797179315 0.433739908960731 0.775700997059865 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 5/1489 54/18639 0.0925925925925926 1.15905529438102 0.434777989929168 0.775701345650968 GO:0031492 nucleosomal DNA binding 4/1489 42/18639 0.0952380952380952 1.19217115993476 0.435099790724469 0.775701345650968 GO:0001221 transcription coregulator binding 10/1489 115/18639 0.0869565217391304 1.08850410254913 0.438219160872917 0.778145496887231 GO:0015291 secondary active transmembrane transporter activity 24/1489 287/18639 0.0836236933797909 1.04678443311345 0.438421254931277 0.778145496887231 GO:0015081 sodium ion transmembrane transporter activity 14/1489 164/18639 0.0853658536585366 1.06859244213664 0.438516699823391 0.778145496887231 GO:0004722 protein serine/threonine phosphatase activity 9/1489 103/18639 0.087378640776699 1.09378810304694 0.440615231562014 0.779444929011252 GO:0005253 monoatomic anion channel activity 9/1489 103/18639 0.087378640776699 1.09378810304694 0.440615231562014 0.779444929011252 GO:0046873 metal ion transmembrane transporter activity 37/1489 450/18639 0.0822222222222222 1.02924110141034 0.452137725113794 0.788413571441991 GO:0005245 voltage-gated calcium channel activity 4/1489 43/18639 0.0930232558139535 1.1644462492386 0.453304156781316 0.788413571441991 GO:0070273 phosphatidylinositol-4-phosphate binding 3/1489 31/18639 0.0967741935483871 1.21139972703048 0.455310185463809 0.788413571441991 GO:0070325 lipoprotein particle receptor binding 3/1489 31/18639 0.0967741935483871 1.21139972703048 0.455310185463809 0.788413571441991 GO:0003756 protein disulfide isomerase activity 2/1489 19/18639 0.105263157894737 1.31766286098052 0.455358933900326 0.788413571441991 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 2/1489 19/18639 0.105263157894737 1.31766286098052 0.455358933900326 0.788413571441991 GO:0008381 mechanosensitive monoatomic ion channel activity 2/1489 19/18639 0.105263157894737 1.31766286098052 0.455358933900326 0.788413571441991 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 2/1489 19/18639 0.105263157894737 1.31766286098052 0.455358933900326 0.788413571441991 GO:0016918 retinal binding 2/1489 19/18639 0.105263157894737 1.31766286098052 0.455358933900326 0.788413571441991 GO:0022840 leak channel activity 2/1489 19/18639 0.105263157894737 1.31766286098052 0.455358933900326 0.788413571441991 GO:0022842 narrow pore channel activity 2/1489 19/18639 0.105263157894737 1.31766286098052 0.455358933900326 0.788413571441991 GO:0034987 immunoglobulin receptor binding 2/1489 19/18639 0.105263157894737 1.31766286098052 0.455358933900326 0.788413571441991 GO:0042834 peptidoglycan binding 2/1489 19/18639 0.105263157894737 1.31766286098052 0.455358933900326 0.788413571441991 GO:0046624 sphingolipid transporter activity 2/1489 19/18639 0.105263157894737 1.31766286098052 0.455358933900326 0.788413571441991 GO:0030547 signaling receptor inhibitor activity 4/1489 44/18639 0.0909090909090909 1.13798156175591 0.47131109513734 0.814796908411674 GO:0008378 galactosyltransferase activity 3/1489 32/18639 0.09375 1.17354348556078 0.476526708025216 0.816391852637796 GO:0015106 bicarbonate transmembrane transporter activity 3/1489 32/18639 0.09375 1.17354348556078 0.476526708025216 0.816391852637796 GO:0022884 macromolecule transmembrane transporter activity 3/1489 32/18639 0.09375 1.17354348556078 0.476526708025216 0.816391852637796 GO:0031369 translation initiation factor binding 3/1489 32/18639 0.09375 1.17354348556078 0.476526708025216 0.816391852637796 GO:0051059 NF-kappaB binding 3/1489 32/18639 0.09375 1.17354348556078 0.476526708025216 0.816391852637796 GO:0070717 poly-purine tract binding 3/1489 32/18639 0.09375 1.17354348556078 0.476526708025216 0.816391852637796 GO:0001972 retinoic acid binding 2/1489 20/18639 0.1 1.2517797179315 0.48246747359465 0.820410413370336 GO:0005326 neurotransmitter transmembrane transporter activity 2/1489 20/18639 0.1 1.2517797179315 0.48246747359465 0.820410413370336 GO:0016408 C-acyltransferase activity 2/1489 20/18639 0.1 1.2517797179315 0.48246747359465 0.820410413370336 GO:0030742 GTP-dependent protein binding 2/1489 20/18639 0.1 1.2517797179315 0.48246747359465 0.820410413370336 GO:0140664 ATP-dependent DNA damage sensor activity 2/1489 20/18639 0.1 1.2517797179315 0.48246747359465 0.820410413370336 GO:0008237 metallopeptidase activity 15/1489 184/18639 0.0815217391304348 1.02047259613981 0.506609138149201 0.854865794349139 GO:0005123 death receptor binding 2/1489 21/18639 0.0952380952380952 1.19217115993476 0.508723816269119 0.854865794349139 GO:0005248 voltage-gated sodium channel activity 2/1489 21/18639 0.0952380952380952 1.19217115993476 0.508723816269119 0.854865794349139 GO:0010314 phosphatidylinositol-5-phosphate binding 2/1489 21/18639 0.0952380952380952 1.19217115993476 0.508723816269119 0.854865794349139 GO:0015125 bile acid transmembrane transporter activity 2/1489 21/18639 0.0952380952380952 1.19217115993476 0.508723816269119 0.854865794349139 GO:0036122 BMP binding 2/1489 21/18639 0.0952380952380952 1.19217115993476 0.508723816269119 0.854865794349139 GO:0061891 calcium ion sensor activity 2/1489 21/18639 0.0952380952380952 1.19217115993476 0.508723816269119 0.854865794349139 GO:0070182 DNA polymerase binding 2/1489 21/18639 0.0952380952380952 1.19217115993476 0.508723816269119 0.854865794349139 GO:0030594 neurotransmitter receptor activity 8/1489 97/18639 0.0824742268041237 1.03239564365484 0.516230964994682 0.864933037096361 GO:0030332 cyclin binding 3/1489 34/18639 0.0882352941176471 1.10451151582191 0.517746945080469 0.864933037096361 GO:0051427 hormone receptor binding 3/1489 34/18639 0.0882352941176471 1.10451151582191 0.517746945080469 0.864933037096361 GO:0090482 vitamin transmembrane transporter activity 3/1489 34/18639 0.0882352941176471 1.10451151582191 0.517746945080469 0.864933037096361 GO:0043495 protein-membrane adaptor activity 4/1489 47/18639 0.0851063829787234 1.06534444079276 0.523877247305857 0.873894647918103 GO:0042626 ATPase-coupled transmembrane transporter activity 8/1489 98/18639 0.0816326530612245 1.02186099422979 0.528128364887718 0.879699947937059 GO:0015377 chloride:monoatomic cation symporter activity 2/1489 22/18639 0.0909090909090909 1.13798156175591 0.534091056395564 0.884573005853533 GO:0050321 tau-protein kinase activity 2/1489 22/18639 0.0909090909090909 1.13798156175591 0.534091056395564 0.884573005853533 GO:0140784 metal ion sensor activity 2/1489 22/18639 0.0909090909090909 1.13798156175591 0.534091056395564 0.884573005853533 GO:0005343 organic acid:sodium symporter activity 3/1489 35/18639 0.0857142857142857 1.07295404394128 0.537687458805575 0.884573005853533 GO:0019905 syntaxin binding 5/1489 61/18639 0.0819672131147541 1.02604894912418 0.543757298162634 0.884573005853533 GO:0003684 damaged DNA binding 6/1489 74/18639 0.0810810810810811 1.01495652805257 0.546505422940326 0.884573005853533 GO:0031491 nucleosome binding 6/1489 74/18639 0.0810810810810811 1.01495652805257 0.546505422940326 0.884573005853533 GO:0001217 DNA-binding transcription repressor activity 22/1489 278/18639 0.079136690647482 0.990617042967372 0.550921936352305 0.884573005853533 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/1489 36/18639 0.0833333333333333 1.04314976494291 0.55714720351366 0.884573005853533 GO:0005484 SNAP receptor activity 3/1489 36/18639 0.0833333333333333 1.04314976494291 0.55714720351366 0.884573005853533 GO:0016409 palmitoyltransferase activity 3/1489 36/18639 0.0833333333333333 1.04314976494291 0.55714720351366 0.884573005853533 GO:0045505 dynein intermediate chain binding 3/1489 36/18639 0.0833333333333333 1.04314976494291 0.55714720351366 0.884573005853533 GO:0001222 transcription corepressor binding 4/1489 49/18639 0.0816326530612245 1.02186099422979 0.557481623744121 0.884573005853533 GO:0016763 pentosyltransferase activity 4/1489 49/18639 0.0816326530612245 1.02186099422979 0.557481623744121 0.884573005853533 GO:0005283 amino acid:sodium symporter activity 2/1489 23/18639 0.0869565217391304 1.08850410254913 0.558543612850755 0.884573005853533 GO:0019003 GDP binding 6/1489 75/18639 0.08 1.0014237743452 0.559928000340869 0.884573005853533 GO:0016757 glycosyltransferase activity 21/1489 267/18639 0.0786516853932584 0.984545845564099 0.5629195434493 0.884573005853533 GO:0005319 lipid transporter activity 14/1489 178/18639 0.0786516853932584 0.984545845564099 0.564575139348646 0.884573005853533 GO:0001094 TFIID-class transcription factor complex binding 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0003796 lysozyme activity 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0005131 growth hormone receptor binding 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0005522 profilin binding 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0005528 FK506 binding 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0008140 cAMP response element binding protein binding 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0008519 ammonium channel activity 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0019531 oxalate transmembrane transporter activity 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0032052 bile acid binding 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0032356 oxidized DNA binding 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0035374 chondroitin sulfate binding 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0042166 acetylcholine binding 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0043121 neurotrophin binding 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0043208 glycosphingolipid binding 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0043295 glutathione binding 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0047429 nucleoside triphosphate diphosphatase activity 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0051378 serotonin binding 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0070097 delta-catenin binding 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/1489 10/18639 0.1 1.2517797179315 0.565165399883633 0.884573005853533 GO:0001653 peptide receptor activity 10/1489 128/18639 0.078125 0.977952904633983 0.576711191832204 0.898307438316564 GO:0005315 phosphate transmembrane transporter activity 2/1489 24/18639 0.0833333333333333 1.04314976494291 0.582065657204054 0.898307438316564 GO:0015149 hexose transmembrane transporter activity 2/1489 24/18639 0.0833333333333333 1.04314976494291 0.582065657204054 0.898307438316564 GO:0015295 solute:proton symporter activity 2/1489 24/18639 0.0833333333333333 1.04314976494291 0.582065657204054 0.898307438316564 GO:0035035 histone acetyltransferase binding 2/1489 24/18639 0.0833333333333333 1.04314976494291 0.582065657204054 0.898307438316564 GO:0050699 WW domain binding 2/1489 24/18639 0.0833333333333333 1.04314976494291 0.582065657204054 0.898307438316564 GO:0055056 D-glucose transmembrane transporter activity 2/1489 24/18639 0.0833333333333333 1.04314976494291 0.582065657204054 0.898307438316564 GO:0140612 DNA damage sensor activity 2/1489 24/18639 0.0833333333333333 1.04314976494291 0.582065657204054 0.898307438316564 GO:0015294 solute:monoatomic cation symporter activity 9/1489 116/18639 0.0775862068965517 0.971208401843403 0.586205689175719 0.898307438316564 GO:0016597 amino acid binding 4/1489 51/18639 0.0784313725490196 0.98178801406392 0.58976490859456 0.898307438316564 GO:0042162 telomeric DNA binding 3/1489 38/18639 0.0789473684210526 0.988247145735393 0.594546647889722 0.898307438316564 GO:0000099 sulfur amino acid transmembrane transporter activity 1/1489 11/18639 0.0909090909090909 1.13798156175591 0.59992135670221 0.898307438316564 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/1489 11/18639 0.0909090909090909 1.13798156175591 0.59992135670221 0.898307438316564 GO:0004016 adenylate cyclase activity 1/1489 11/18639 0.0909090909090909 1.13798156175591 0.59992135670221 0.898307438316564 GO:0005536 D-glucose binding 1/1489 11/18639 0.0909090909090909 1.13798156175591 0.59992135670221 0.898307438316564 GO:0008199 ferric iron binding 1/1489 11/18639 0.0909090909090909 1.13798156175591 0.59992135670221 0.898307438316564 GO:0008432 JUN kinase binding 1/1489 11/18639 0.0909090909090909 1.13798156175591 0.59992135670221 0.898307438316564 GO:0008503 benzodiazepine receptor activity 1/1489 11/18639 0.0909090909090909 1.13798156175591 0.59992135670221 0.898307438316564 GO:0008526 phosphatidylinositol transfer activity 1/1489 11/18639 0.0909090909090909 1.13798156175591 0.59992135670221 0.898307438316564 GO:0016594 glycine binding 1/1489 11/18639 0.0909090909090909 1.13798156175591 0.59992135670221 0.898307438316564 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/1489 11/18639 0.0909090909090909 1.13798156175591 0.59992135670221 0.898307438316564 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/1489 11/18639 0.0909090909090909 1.13798156175591 0.59992135670221 0.898307438316564 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/1489 11/18639 0.0909090909090909 1.13798156175591 0.59992135670221 0.898307438316564 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/1489 11/18639 0.0909090909090909 1.13798156175591 0.59992135670221 0.898307438316564 GO:0032050 clathrin heavy chain binding 1/1489 11/18639 0.0909090909090909 1.13798156175591 0.59992135670221 0.898307438316564 GO:0032794 GTPase activating protein binding 1/1489 11/18639 0.0909090909090909 1.13798156175591 0.59992135670221 0.898307438316564 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/1489 11/18639 0.0909090909090909 1.13798156175591 0.59992135670221 0.898307438316564 GO:0042608 T cell receptor binding 1/1489 11/18639 0.0909090909090909 1.13798156175591 0.59992135670221 0.898307438316564 GO:0045294 alpha-catenin binding 1/1489 11/18639 0.0909090909090909 1.13798156175591 0.59992135670221 0.898307438316564 GO:0097493 structural molecule activity conferring elasticity 1/1489 11/18639 0.0909090909090909 1.13798156175591 0.59992135670221 0.898307438316564 GO:0099508 voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/1489 11/18639 0.0909090909090909 1.13798156175591 0.59992135670221 0.898307438316564 GO:0140537 transcription regulator activator activity 1/1489 11/18639 0.0909090909090909 1.13798156175591 0.59992135670221 0.898307438316564 GO:1900750 oligopeptide binding 1/1489 11/18639 0.0909090909090909 1.13798156175591 0.59992135670221 0.898307438316564 GO:0015296 monoatomic anion:monoatomic cation symporter activity 2/1489 25/18639 0.08 1.0014237743452 0.604649720585384 0.903017449198852 GO:0120020 cholesterol transfer activity 2/1489 25/18639 0.08 1.0014237743452 0.604649720585384 0.903017449198852 GO:0015370 solute:sodium symporter activity 6/1489 79/18639 0.0759493670886076 0.95071877311253 0.611625247805061 0.90577771313112 GO:0016835 carbon-oxygen lyase activity 6/1489 79/18639 0.0759493670886076 0.95071877311253 0.611625247805061 0.90577771313112 GO:0016776 phosphotransferase activity, phosphate group as acceptor 3/1489 39/18639 0.0769230769230769 0.962907475331921 0.612456970590353 0.90577771313112 GO:0051018 protein kinase A binding 4/1489 53/18639 0.0754716981132075 0.944739409759621 0.620620343224105 0.90577771313112 GO:0008157 protein phosphatase 1 binding 2/1489 26/18639 0.0769230769230769 0.962907475331921 0.626295460660731 0.90577771313112 GO:0015145 monosaccharide transmembrane transporter activity 2/1489 26/18639 0.0769230769230769 0.962907475331921 0.626295460660731 0.90577771313112 GO:0034237 protein kinase A regulatory subunit binding 2/1489 26/18639 0.0769230769230769 0.962907475331921 0.626295460660731 0.90577771313112 GO:0051139 metal cation:proton antiporter activity 2/1489 26/18639 0.0769230769230769 0.962907475331921 0.626295460660731 0.90577771313112 GO:0015144 carbohydrate transmembrane transporter activity 3/1489 40/18639 0.075 0.938834788448623 0.62982717292288 0.90577771313112 GO:0050997 quaternary ammonium group binding 3/1489 40/18639 0.075 0.938834788448623 0.62982717292288 0.90577771313112 GO:0061791 GTPase motor activity 3/1489 40/18639 0.075 0.938834788448623 0.62982717292288 0.90577771313112 GO:1990606 membrane scission GTPase motor activity 3/1489 40/18639 0.075 0.938834788448623 0.62982717292288 0.90577771313112 GO:0004032 aldose reductase (NADPH) activity 1/1489 12/18639 0.0833333333333333 1.04314976494291 0.63190101634739 0.90577771313112 GO:0005049 nuclear export signal receptor activity 1/1489 12/18639 0.0833333333333333 1.04314976494291 0.63190101634739 0.90577771313112 GO:0005247 voltage-gated chloride channel activity 1/1489 12/18639 0.0833333333333333 1.04314976494291 0.63190101634739 0.90577771313112 GO:0005527 macrolide binding 1/1489 12/18639 0.0833333333333333 1.04314976494291 0.63190101634739 0.90577771313112 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/1489 12/18639 0.0833333333333333 1.04314976494291 0.63190101634739 0.90577771313112 GO:0008603 cAMP-dependent protein kinase regulator activity 1/1489 12/18639 0.0833333333333333 1.04314976494291 0.63190101634739 0.90577771313112 GO:0015269 calcium-activated potassium channel activity 1/1489 12/18639 0.0833333333333333 1.04314976494291 0.63190101634739 0.90577771313112 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/1489 12/18639 0.0833333333333333 1.04314976494291 0.63190101634739 0.90577771313112 GO:0035197 siRNA binding 1/1489 12/18639 0.0833333333333333 1.04314976494291 0.63190101634739 0.90577771313112 GO:0035259 nuclear glucocorticoid receptor binding 1/1489 12/18639 0.0833333333333333 1.04314976494291 0.63190101634739 0.90577771313112 GO:0035497 cAMP response element binding 1/1489 12/18639 0.0833333333333333 1.04314976494291 0.63190101634739 0.90577771313112 GO:0070679 inositol 1,4,5 trisphosphate binding 1/1489 12/18639 0.0833333333333333 1.04314976494291 0.63190101634739 0.90577771313112 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/1489 12/18639 0.0833333333333333 1.04314976494291 0.63190101634739 0.90577771313112 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/1489 12/18639 0.0833333333333333 1.04314976494291 0.63190101634739 0.90577771313112 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/1489 12/18639 0.0833333333333333 1.04314976494291 0.63190101634739 0.90577771313112 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/1489 12/18639 0.0833333333333333 1.04314976494291 0.63190101634739 0.90577771313112 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/1489 12/18639 0.0833333333333333 1.04314976494291 0.63190101634739 0.90577771313112 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/1489 12/18639 0.0833333333333333 1.04314976494291 0.63190101634739 0.90577771313112 GO:0140900 chloride:bicarbonate antiporter activity 1/1489 12/18639 0.0833333333333333 1.04314976494291 0.63190101634739 0.90577771313112 GO:1990817 poly(A) RNA polymerase activity 1/1489 12/18639 0.0833333333333333 1.04314976494291 0.63190101634739 0.90577771313112 GO:0015101 organic cation transmembrane transporter activity 6/1489 81/18639 0.0740740740740741 0.927244235504813 0.636163707077208 0.906949815626046 GO:0003924 GTPase activity 25/1489 331/18639 0.0755287009063444 0.945452959162763 0.645658525175335 0.906949815626046 GO:0001727 lipid kinase activity 3/1489 41/18639 0.0731707317073171 0.915936378974266 0.646650730076012 0.906949815626046 GO:0017080 sodium channel regulator activity 3/1489 41/18639 0.0731707317073171 0.915936378974266 0.646650730076012 0.906949815626046 GO:0042287 MHC protein binding 3/1489 41/18639 0.0731707317073171 0.915936378974266 0.646650730076012 0.906949815626046 GO:0140318 protein transporter activity 3/1489 41/18639 0.0731707317073171 0.915936378974266 0.646650730076012 0.906949815626046 GO:0008395 steroid hydroxylase activity 2/1489 27/18639 0.0740740740740741 0.927244235504813 0.647008572051245 0.906949815626046 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 2/1489 27/18639 0.0740740740740741 0.927244235504813 0.647008572051245 0.906949815626046 GO:0008528 G protein-coupled peptide receptor activity 9/1489 122/18639 0.0737704918032787 0.92344405421176 0.647196956041036 0.906949815626046 GO:0098960 postsynaptic neurotransmitter receptor activity 5/1489 69/18639 0.072463768115942 0.907086752124274 0.654611058354452 0.906949815626046 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 20/1489 268/18639 0.0746268656716418 0.934163968605595 0.658262889463259 0.906949815626046 GO:0004222 metalloendopeptidase activity 8/1489 110/18639 0.0727272727272727 0.910385249404726 0.660445312923184 0.906949815626046 GO:0019842 vitamin binding 11/1489 150/18639 0.0733333333333333 0.917971793149765 0.660556122357776 0.906949815626046 GO:0004465 lipoprotein lipase activity 1/1489 13/18639 0.0769230769230769 0.962907475331921 0.661326011604744 0.906949815626046 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/1489 13/18639 0.0769230769230769 0.962907475331921 0.661326011604744 0.906949815626046 GO:0005172 vascular endothelial growth factor receptor binding 1/1489 13/18639 0.0769230769230769 0.962907475331921 0.661326011604744 0.906949815626046 GO:0008253 5'-nucleotidase activity 1/1489 13/18639 0.0769230769230769 0.962907475331921 0.661326011604744 0.906949815626046 GO:0008417 fucosyltransferase activity 1/1489 13/18639 0.0769230769230769 0.962907475331921 0.661326011604744 0.906949815626046 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/1489 13/18639 0.0769230769230769 0.962907475331921 0.661326011604744 0.906949815626046 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/1489 13/18639 0.0769230769230769 0.962907475331921 0.661326011604744 0.906949815626046 GO:0019104 DNA N-glycosylase activity 1/1489 13/18639 0.0769230769230769 0.962907475331921 0.661326011604744 0.906949815626046 GO:0032396 inhibitory MHC class I receptor activity 1/1489 13/18639 0.0769230769230769 0.962907475331921 0.661326011604744 0.906949815626046 GO:0043560 insulin receptor substrate binding 1/1489 13/18639 0.0769230769230769 0.962907475331921 0.661326011604744 0.906949815626046 GO:0045159 myosin II binding 1/1489 13/18639 0.0769230769230769 0.962907475331921 0.661326011604744 0.906949815626046 GO:0046974 histone H3K9 methyltransferase activity 1/1489 13/18639 0.0769230769230769 0.962907475331921 0.661326011604744 0.906949815626046 GO:0051011 microtubule minus-end binding 1/1489 13/18639 0.0769230769230769 0.962907475331921 0.661326011604744 0.906949815626046 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/1489 13/18639 0.0769230769230769 0.962907475331921 0.661326011604744 0.906949815626046 GO:0061459 L-arginine transmembrane transporter activity 1/1489 13/18639 0.0769230769230769 0.962907475331921 0.661326011604744 0.906949815626046 GO:0071837 HMG box domain binding 1/1489 13/18639 0.0769230769230769 0.962907475331921 0.661326011604744 0.906949815626046 GO:0097157 pre-mRNA intronic binding 1/1489 13/18639 0.0769230769230769 0.962907475331921 0.661326011604744 0.906949815626046 GO:0140333 glycerophospholipid flippase activity 1/1489 13/18639 0.0769230769230769 0.962907475331921 0.661326011604744 0.906949815626046 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/1489 13/18639 0.0769230769230769 0.962907475331921 0.661326011604744 0.906949815626046 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/1489 13/18639 0.0769230769230769 0.962907475331921 0.661326011604744 0.906949815626046 GO:0140852 histone ubiquitin ligase activity 1/1489 13/18639 0.0769230769230769 0.962907475331921 0.661326011604744 0.906949815626046 GO:1901338 catecholamine binding 1/1489 13/18639 0.0769230769230769 0.962907475331921 0.661326011604744 0.906949815626046 GO:0016859 cis-trans isomerase activity 3/1489 42/18639 0.0714285714285714 0.89412836995107 0.6629238792569 0.906949815626046 GO:0019894 kinesin binding 3/1489 42/18639 0.0714285714285714 0.89412836995107 0.6629238792569 0.906949815626046 GO:0048487 beta-tubulin binding 3/1489 42/18639 0.0714285714285714 0.89412836995107 0.6629238792569 0.906949815626046 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 4/1489 56/18639 0.0714285714285714 0.89412836995107 0.664067412398084 0.907426248558339 GO:0003713 transcription coactivator activity 19/1489 256/18639 0.07421875 0.929055259402283 0.665360378083297 0.90810549209694 GO:0051119 sugar transmembrane transporter activity 2/1489 28/18639 0.0714285714285714 0.89412836995107 0.66679982516997 0.908423920836984 GO:0016782 transferase activity, transferring sulphur-containing groups 5/1489 70/18639 0.0714285714285714 0.89412836995107 0.66718601723172 0.908423920836984 GO:0004712 protein serine/threonine/tyrosine kinase activity 3/1489 43/18639 0.0697674418604651 0.873334686928952 0.678645358442569 0.918672204122216 GO:0004181 metallocarboxypeptidase activity 2/1489 29/18639 0.0689655172413793 0.863296357194136 0.685684219933206 0.918672204122216 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 2/1489 29/18639 0.0689655172413793 0.863296357194136 0.685684219933206 0.918672204122216 GO:0005416 amino acid:monoatomic cation symporter activity 2/1489 29/18639 0.0689655172413793 0.863296357194136 0.685684219933206 0.918672204122216 GO:0035250 UDP-galactosyltransferase activity 2/1489 29/18639 0.0689655172413793 0.863296357194136 0.685684219933206 0.918672204122216 GO:0097472 cyclin-dependent protein kinase activity 2/1489 29/18639 0.0689655172413793 0.863296357194136 0.685684219933206 0.918672204122216 GO:0004705 JUN kinase activity 1/1489 14/18639 0.0714285714285714 0.89412836995107 0.688400293185359 0.918672204122216 GO:0005313 L-glutamate transmembrane transporter activity 1/1489 14/18639 0.0714285714285714 0.89412836995107 0.688400293185359 0.918672204122216 GO:0008559 ABC-type xenobiotic transporter activity 1/1489 14/18639 0.0714285714285714 0.89412836995107 0.688400293185359 0.918672204122216 GO:0015386 potassium:proton antiporter activity 1/1489 14/18639 0.0714285714285714 0.89412836995107 0.688400293185359 0.918672204122216 GO:0015926 glucosidase activity 1/1489 14/18639 0.0714285714285714 0.89412836995107 0.688400293185359 0.918672204122216 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/1489 14/18639 0.0714285714285714 0.89412836995107 0.688400293185359 0.918672204122216 GO:0043176 amine binding 1/1489 14/18639 0.0714285714285714 0.89412836995107 0.688400293185359 0.918672204122216 GO:0046030 inositol trisphosphate phosphatase activity 1/1489 14/18639 0.0714285714285714 0.89412836995107 0.688400293185359 0.918672204122216 GO:0061783 peptidoglycan muralytic activity 1/1489 14/18639 0.0714285714285714 0.89412836995107 0.688400293185359 0.918672204122216 GO:0070742 C2H2 zinc finger domain binding 1/1489 14/18639 0.0714285714285714 0.89412836995107 0.688400293185359 0.918672204122216 GO:1901474 azole transmembrane transporter activity 1/1489 14/18639 0.0714285714285714 0.89412836995107 0.688400293185359 0.918672204122216 GO:0003712 transcription coregulator activity 37/1489 495/18639 0.0747474747474747 0.935673728554857 0.689604470927759 0.919204090337118 GO:0001223 transcription coactivator binding 3/1489 44/18639 0.0681818181818182 0.85348617131693 0.69381615819661 0.920516554072479 GO:0016790 thiolester hydrolase activity 3/1489 44/18639 0.0681818181818182 0.85348617131693 0.69381615819661 0.920516554072479 GO:0030020 extracellular matrix structural constituent conferring tensile strength 3/1489 44/18639 0.0681818181818182 0.85348617131693 0.69381615819661 0.920516554072479 GO:0043014 alpha-tubulin binding 3/1489 44/18639 0.0681818181818182 0.85348617131693 0.69381615819661 0.920516554072479 GO:0016769 transferase activity, transferring nitrogenous groups 2/1489 30/18639 0.0666666666666667 0.834519811954332 0.703680242145525 0.931437536297035 GO:0048019 receptor antagonist activity 2/1489 30/18639 0.0666666666666667 0.834519811954332 0.703680242145525 0.931437536297035 GO:0042605 peptide antigen binding 3/1489 45/18639 0.0666666666666667 0.834519811954332 0.708439287009581 0.935503984621568 GO:0000774 adenyl-nucleotide exchange factor activity 1/1489 15/18639 0.0666666666666667 0.834519811954332 0.713311539544929 0.935503984621568 GO:0004559 alpha-mannosidase activity 1/1489 15/18639 0.0666666666666667 0.834519811954332 0.713311539544929 0.935503984621568 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/1489 15/18639 0.0666666666666667 0.834519811954332 0.713311539544929 0.935503984621568 GO:0008252 nucleotidase activity 1/1489 15/18639 0.0666666666666667 0.834519811954332 0.713311539544929 0.935503984621568 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/1489 15/18639 0.0666666666666667 0.834519811954332 0.713311539544929 0.935503984621568 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 1/1489 15/18639 0.0666666666666667 0.834519811954332 0.713311539544929 0.935503984621568 GO:0140161 monocarboxylate:sodium symporter activity 1/1489 15/18639 0.0666666666666667 0.834519811954332 0.713311539544929 0.935503984621568 GO:0016758 hexosyltransferase activity 14/1489 197/18639 0.0710659898477157 0.889589647260963 0.714629881512897 0.936156940076023 GO:0001098 basal transcription machinery binding 4/1489 60/18639 0.0666666666666667 0.834519811954332 0.716509504321524 0.936468893964329 GO:0001099 basal RNA polymerase II transcription machinery binding 4/1489 60/18639 0.0666666666666667 0.834519811954332 0.716509504321524 0.936468893964329 GO:0005310 dicarboxylic acid transmembrane transporter activity 2/1489 31/18639 0.0645161290322581 0.807599818020321 0.720809211571851 0.939935211889693 GO:0047499 calcium-independent phospholipase A2 activity 2/1489 31/18639 0.0645161290322581 0.807599818020321 0.720809211571851 0.939935211889693 GO:0008194 UDP-glycosyltransferase activity 10/1489 145/18639 0.0689655172413793 0.863296357194136 0.730699187382912 0.942853213198724 GO:0019001 guanyl nucleotide binding 29/1489 400/18639 0.0725 0.907540295500336 0.735398519358827 0.942853213198724 GO:0032561 guanyl ribonucleotide binding 29/1489 400/18639 0.0725 0.907540295500336 0.735398519358827 0.942853213198724 GO:0004707 MAP kinase activity 1/1489 16/18639 0.0625 0.782362323707186 0.736232454365462 0.942853213198724 GO:0004708 MAP kinase kinase activity 1/1489 16/18639 0.0625 0.782362323707186 0.736232454365462 0.942853213198724 GO:0008142 oxysterol binding 1/1489 16/18639 0.0625 0.782362323707186 0.736232454365462 0.942853213198724 GO:0015378 sodium:chloride symporter activity 1/1489 16/18639 0.0625 0.782362323707186 0.736232454365462 0.942853213198724 GO:0015385 sodium:proton antiporter activity 1/1489 16/18639 0.0625 0.782362323707186 0.736232454365462 0.942853213198724 GO:0034450 ubiquitin-ubiquitin ligase activity 1/1489 16/18639 0.0625 0.782362323707186 0.736232454365462 0.942853213198724 GO:0043023 ribosomal large subunit binding 1/1489 16/18639 0.0625 0.782362323707186 0.736232454365462 0.942853213198724 GO:0140327 flippase activity 1/1489 16/18639 0.0625 0.782362323707186 0.736232454365462 0.942853213198724 GO:0140328 floppase activity 1/1489 16/18639 0.0625 0.782362323707186 0.736232454365462 0.942853213198724 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/1489 32/18639 0.0625 0.782362323707186 0.737094711808293 0.942853213198724 GO:0042910 xenobiotic transmembrane transporter activity 2/1489 32/18639 0.0625 0.782362323707186 0.737094711808293 0.942853213198724 GO:0047498 calcium-dependent phospholipase A2 activity 2/1489 32/18639 0.0625 0.782362323707186 0.737094711808293 0.942853213198724 GO:0120015 sterol transfer activity 2/1489 32/18639 0.0625 0.782362323707186 0.737094711808293 0.942853213198724 GO:0140142 nucleocytoplasmic carrier activity 2/1489 32/18639 0.0625 0.782362323707186 0.737094711808293 0.942853213198724 GO:0022832 voltage-gated channel activity 12/1489 175/18639 0.0685714285714286 0.858363235153027 0.749997235746332 0.955867651655213 GO:0022824 transmitter-gated monoatomic ion channel activity 4/1489 63/18639 0.0634920634920635 0.79478077328984 0.751705256042814 0.955867651655213 GO:0022835 transmitter-gated channel activity 4/1489 63/18639 0.0634920634920635 0.79478077328984 0.751705256042814 0.955867651655213 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2/1489 33/18639 0.0606060606060606 0.758654374503938 0.752562093056648 0.955867651655213 GO:0052689 carboxylic ester hydrolase activity 6/1489 92/18639 0.0652173913043478 0.816378076911846 0.753574527511001 0.955867651655213 GO:0005525 GTP binding 27/1489 378/18639 0.0714285714285714 0.89412836995107 0.75668698049182 0.955867651655213 GO:0004550 nucleoside diphosphate kinase activity 1/1489 17/18639 0.0588235294117647 0.73634101054794 0.757321960645322 0.955867651655213 GO:0005092 GDP-dissociation inhibitor activity 1/1489 17/18639 0.0588235294117647 0.73634101054794 0.757321960645322 0.955867651655213 GO:0016018 cyclosporin A binding 1/1489 17/18639 0.0588235294117647 0.73634101054794 0.757321960645322 0.955867651655213 GO:0030548 acetylcholine receptor regulator activity 1/1489 17/18639 0.0588235294117647 0.73634101054794 0.757321960645322 0.955867651655213 GO:0032977 membrane insertase activity 1/1489 17/18639 0.0588235294117647 0.73634101054794 0.757321960645322 0.955867651655213 GO:0045236 CXCR chemokine receptor binding 1/1489 17/18639 0.0588235294117647 0.73634101054794 0.757321960645322 0.955867651655213 GO:0051213 dioxygenase activity 6/1489 93/18639 0.0645161290322581 0.807599818020321 0.762723600322552 0.961621688362466 GO:0015020 glucuronosyltransferase activity 2/1489 34/18639 0.0588235294117647 0.73634101054794 0.767238039805159 0.964357679955876 GO:0160215 deacylase activity 4/1489 65/18639 0.0615384615384615 0.770325980265537 0.773239064538245 0.964357679955876 GO:0048020 CCR chemokine receptor binding 3/1489 50/18639 0.06 0.751067830758898 0.773559739362281 0.964357679955876 GO:0000900 mRNA regulatory element binding translation repressor activity 1/1489 18/18639 0.0555555555555556 0.69543317662861 0.77672629963142 0.964357679955876 GO:0008308 voltage-gated monoatomic anion channel activity 1/1489 18/18639 0.0555555555555556 0.69543317662861 0.77672629963142 0.964357679955876 GO:0008409 5'-3' exonuclease activity 1/1489 18/18639 0.0555555555555556 0.69543317662861 0.77672629963142 0.964357679955876 GO:0015373 monoatomic anion:sodium symporter activity 1/1489 18/18639 0.0555555555555556 0.69543317662861 0.77672629963142 0.964357679955876 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/1489 18/18639 0.0555555555555556 0.69543317662861 0.77672629963142 0.964357679955876 GO:0016854 racemase and epimerase activity 1/1489 18/18639 0.0555555555555556 0.69543317662861 0.77672629963142 0.964357679955876 GO:0022851 GABA-gated chloride ion channel activity 1/1489 18/18639 0.0555555555555556 0.69543317662861 0.77672629963142 0.964357679955876 GO:0050811 GABA receptor binding 1/1489 18/18639 0.0555555555555556 0.69543317662861 0.77672629963142 0.964357679955876 GO:0099602 neurotransmitter receptor regulator activity 1/1489 18/18639 0.0555555555555556 0.69543317662861 0.77672629963142 0.964357679955876 GO:1901611 phosphatidylglycerol binding 1/1489 18/18639 0.0555555555555556 0.69543317662861 0.77672629963142 0.964357679955876 GO:1990381 ubiquitin-specific protease binding 1/1489 18/18639 0.0555555555555556 0.69543317662861 0.77672629963142 0.964357679955876 GO:0004623 phospholipase A2 activity 2/1489 35/18639 0.0571428571428571 0.715302695960856 0.781150196229377 0.965647208989944 GO:0016229 steroid dehydrogenase activity 2/1489 35/18639 0.0571428571428571 0.715302695960856 0.781150196229377 0.965647208989944 GO:0043015 gamma-tubulin binding 2/1489 35/18639 0.0571428571428571 0.715302695960856 0.781150196229377 0.965647208989944 GO:0061631 ubiquitin conjugating enzyme activity 2/1489 35/18639 0.0571428571428571 0.715302695960856 0.781150196229377 0.965647208989944 GO:0003743 translation initiation factor activity 3/1489 51/18639 0.0588235294117647 0.73634101054794 0.785046916285263 0.966541394582402 GO:0016830 carbon-carbon lyase activity 3/1489 51/18639 0.0588235294117647 0.73634101054794 0.785046916285263 0.966541394582402 GO:0003774 cytoskeletal motor activity 10/1489 153/18639 0.065359477124183 0.8181566783866 0.788644533478998 0.966541394582402 GO:0022836 gated channel activity 22/1489 318/18639 0.0691823899371069 0.866011125612986 0.789635934226994 0.966541394582402 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 2/1489 36/18639 0.0555555555555556 0.69543317662861 0.794326842859713 0.966541394582402 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 2/1489 36/18639 0.0555555555555556 0.69543317662861 0.794326842859713 0.966541394582402 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 2/1489 36/18639 0.0555555555555556 0.69543317662861 0.794326842859713 0.966541394582402 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/1489 19/18639 0.0526315789473684 0.658831430490262 0.794580042172036 0.966541394582402 GO:0004890 GABA-A receptor activity 1/1489 19/18639 0.0526315789473684 0.658831430490262 0.794580042172036 0.966541394582402 GO:0005229 intracellularly calcium-gated chloride channel activity 1/1489 19/18639 0.0526315789473684 0.658831430490262 0.794580042172036 0.966541394582402 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/1489 19/18639 0.0526315789473684 0.658831430490262 0.794580042172036 0.966541394582402 GO:0022821 solute:potassium antiporter activity 1/1489 19/18639 0.0526315789473684 0.658831430490262 0.794580042172036 0.966541394582402 GO:0031420 alkali metal ion binding 1/1489 19/18639 0.0526315789473684 0.658831430490262 0.794580042172036 0.966541394582402 GO:0097001 ceramide binding 1/1489 19/18639 0.0526315789473684 0.658831430490262 0.794580042172036 0.966541394582402 GO:0141147 intracellularly calcium-gated channel activity 1/1489 19/18639 0.0526315789473684 0.658831430490262 0.794580042172036 0.966541394582402 GO:0005548 phospholipid transporter activity 4/1489 68/18639 0.0588235294117647 0.73634101054794 0.802745583439172 0.975434196702977 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 3/1489 53/18639 0.0566037735849057 0.708554557319716 0.806572751210092 0.976117098323027 GO:0030280 structural constituent of skin epidermis 2/1489 37/18639 0.0540540540540541 0.676637685368377 0.806796618723965 0.976117098323027 GO:0000339 RNA cap binding 1/1489 20/18639 0.05 0.625889858965749 0.811007019465583 0.976117098323027 GO:0015095 magnesium ion transmembrane transporter activity 1/1489 20/18639 0.05 0.625889858965749 0.811007019465583 0.976117098323027 GO:0015464 acetylcholine receptor activity 1/1489 20/18639 0.05 0.625889858965749 0.811007019465583 0.976117098323027 GO:0016004 phospholipase activator activity 1/1489 20/18639 0.05 0.625889858965749 0.811007019465583 0.976117098323027 GO:0052745 inositol phosphate phosphatase activity 1/1489 20/18639 0.05 0.625889858965749 0.811007019465583 0.976117098323027 GO:0061608 nuclear import signal receptor activity 1/1489 20/18639 0.05 0.625889858965749 0.811007019465583 0.976117098323027 GO:0140939 histone H4 methyltransferase activity 1/1489 20/18639 0.05 0.625889858965749 0.811007019465583 0.976117098323027 GO:0004175 endopeptidase activity 28/1489 405/18639 0.0691358024691358 0.865427953137825 0.81465599772574 0.979475757012718 GO:0017069 snRNA binding 3/1489 54/18639 0.0555555555555556 0.69543317662861 0.816636575899644 0.979792148371707 GO:0050661 NADP binding 3/1489 54/18639 0.0555555555555556 0.69543317662861 0.816636575899644 0.979792148371707 GO:0015276 ligand-gated monoatomic ion channel activity 12/1489 186/18639 0.0645161290322581 0.807599818020321 0.818026933805388 0.980429339781457 GO:0008234 cysteine-type peptidase activity 12/1489 187/18639 0.0641711229946524 0.803281102415934 0.823458465882654 0.98290330130614 GO:0005244 voltage-gated monoatomic ion channel activity 11/1489 173/18639 0.0635838150289017 0.795929300418871 0.824345672524735 0.98290330130614 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 8/1489 130/18639 0.0615384615384615 0.770325980265537 0.824591793171193 0.98290330130614 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/1489 21/18639 0.0476190476190476 0.59608557996738 0.826121179625406 0.98290330130614 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/1489 21/18639 0.0476190476190476 0.59608557996738 0.826121179625406 0.98290330130614 GO:0015174 basic amino acid transmembrane transporter activity 1/1489 21/18639 0.0476190476190476 0.59608557996738 0.826121179625406 0.98290330130614 GO:0051428 peptide hormone receptor binding 1/1489 21/18639 0.0476190476190476 0.59608557996738 0.826121179625406 0.98290330130614 GO:0022834 ligand-gated channel activity 12/1489 188/18639 0.0638297872340425 0.799008330594573 0.828767525771817 0.985024736360045 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 2/1489 39/18639 0.0512820512820513 0.641938316887947 0.829730516915175 0.985143100728631 GO:0015079 potassium ion transmembrane transporter activity 10/1489 160/18639 0.0625 0.782362323707186 0.831441647527269 0.986148565310409 GO:0015293 symporter activity 9/1489 146/18639 0.0616438356164384 0.771645031601608 0.833741761716914 0.987849792439252 GO:0071949 FAD binding 2/1489 40/18639 0.05 0.625889858965749 0.840251745546348 0.994530333680896 GO:0061659 ubiquitin-like protein ligase activity 25/1489 372/18639 0.0672043010752688 0.841249810437834 0.84360496098557 0.994959107887605 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 4/1489 73/18639 0.0547945205479452 0.685906694756985 0.844926793558021 0.994959107887605 GO:0016877 ligase activity, forming carbon-sulfur bonds 2/1489 41/18639 0.0487804878048781 0.610624252649511 0.850180002749955 0.994959107887605 GO:0061650 ubiquitin-like protein conjugating enzyme activity 2/1489 41/18639 0.0487804878048781 0.610624252649511 0.850180002749955 0.994959107887605 GO:0140828 metal cation:monoatomic cation antiporter activity 2/1489 41/18639 0.0487804878048781 0.610624252649511 0.850180002749955 0.994959107887605 GO:0140104 molecular carrier activity 16/1489 249/18639 0.0642570281124498 0.804356445257187 0.850242074498493 0.994959107887605 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/1489 23/18639 0.0434782608695652 0.544252051274564 0.85282209247509 0.994959107887605 GO:0005212 structural constituent of eye lens 1/1489 23/18639 0.0434782608695652 0.544252051274564 0.85282209247509 0.994959107887605 GO:0008171 O-methyltransferase activity 1/1489 23/18639 0.0434782608695652 0.544252051274564 0.85282209247509 0.994959107887605 GO:0016917 GABA receptor activity 1/1489 23/18639 0.0434782608695652 0.544252051274564 0.85282209247509 0.994959107887605 GO:0042171 lysophosphatidic acid acyltransferase activity 1/1489 23/18639 0.0434782608695652 0.544252051274564 0.85282209247509 0.994959107887605 GO:0071617 lysophospholipid acyltransferase activity 1/1489 23/18639 0.0434782608695652 0.544252051274564 0.85282209247509 0.994959107887605 GO:0099186 structural constituent of postsynapse 1/1489 23/18639 0.0434782608695652 0.544252051274564 0.85282209247509 0.994959107887605 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/1489 23/18639 0.0434782608695652 0.544252051274564 0.85282209247509 0.994959107887605 GO:0008236 serine-type peptidase activity 12/1489 194/18639 0.0618556701030928 0.774296732741133 0.858111752386304 0.997796008554081 GO:0004520 DNA endonuclease activity 2/1489 42/18639 0.0476190476190476 0.59608557996738 0.859542808924608 0.997796008554081 GO:0008307 structural constituent of muscle 2/1489 42/18639 0.0476190476190476 0.59608557996738 0.859542808924608 0.997796008554081 GO:0099094 ligand-gated monoatomic cation channel activity 8/1489 136/18639 0.0588235294117647 0.73634101054794 0.859544547100163 0.997796008554081 GO:0036002 pre-mRNA binding 3/1489 59/18639 0.0508474576271186 0.636498161660084 0.860500676965132 0.997796008554081 GO:0070063 RNA polymerase binding 3/1489 59/18639 0.0508474576271186 0.636498161660084 0.860500676965132 0.997796008554081 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 7/1489 122/18639 0.0573770491803279 0.718234264386925 0.864559663723578 0.99886007068728 GO:0004806 triacylglycerol lipase activity 1/1489 24/18639 0.0416666666666667 0.521574882471457 0.864594111399917 0.99886007068728 GO:0060229 lipase activator activity 1/1489 24/18639 0.0416666666666667 0.521574882471457 0.864594111399917 0.99886007068728 GO:0051536 iron-sulfur cluster binding 4/1489 76/18639 0.0526315789473684 0.658831430490262 0.866387694678816 0.99886007068728 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/1489 43/18639 0.0465116279069767 0.582223124619301 0.868367074801781 0.99886007068728 GO:0061630 ubiquitin protein ligase activity 23/1489 353/18639 0.0651558073654391 0.815607181655084 0.872660867152894 0.99886007068728 GO:0051540 metal cluster binding 4/1489 77/18639 0.051948051948052 0.650275178146233 0.872951407189802 0.99886007068728 GO:0005267 potassium channel activity 7/1489 124/18639 0.0564516129032258 0.706649840767781 0.875107172960487 0.99886007068728 GO:0017171 serine hydrolase activity 12/1489 198/18639 0.0606060606060606 0.758654374503938 0.87537915596369 0.99886007068728 GO:0000030 mannosyltransferase activity 1/1489 25/18639 0.04 0.500711887172599 0.875425127683856 0.99886007068728 GO:0005251 delayed rectifier potassium channel activity 1/1489 25/18639 0.04 0.500711887172599 0.875425127683856 0.99886007068728 GO:0008139 nuclear localization sequence binding 1/1489 25/18639 0.04 0.500711887172599 0.875425127683856 0.99886007068728 GO:0008483 transaminase activity 1/1489 25/18639 0.04 0.500711887172599 0.875425127683856 0.99886007068728 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/1489 25/18639 0.04 0.500711887172599 0.875425127683856 0.99886007068728 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/1489 25/18639 0.04 0.500711887172599 0.875425127683856 0.99886007068728 GO:0019707 protein-cysteine S-acyltransferase activity 1/1489 25/18639 0.04 0.500711887172599 0.875425127683856 0.99886007068728 GO:0001046 core promoter sequence-specific DNA binding 2/1489 44/18639 0.0454545454545455 0.568990780877954 0.876679023211551 0.999291474010369 GO:0051539 4 iron, 4 sulfur cluster binding 2/1489 45/18639 0.0444444444444444 0.556346541302888 0.884504127220945 0.999999999554324 GO:0140303 intramembrane lipid transporter activity 2/1489 45/18639 0.0444444444444444 0.556346541302888 0.884504127220945 0.999999999554324 GO:0004529 DNA exonuclease activity 1/1489 26/18639 0.0384615384615385 0.481453737665961 0.885390314364781 0.999999999554324 GO:0005227 calcium-activated cation channel activity 1/1489 26/18639 0.0384615384615385 0.481453737665961 0.885390314364781 0.999999999554324 GO:0097602 cullin family protein binding 1/1489 26/18639 0.0384615384615385 0.481453737665961 0.885390314364781 0.999999999554324 GO:0120014 phospholipid transfer activity 1/1489 26/18639 0.0384615384615385 0.481453737665961 0.885390314364781 0.999999999554324 GO:0022843 voltage-gated monoatomic cation channel activity 8/1489 143/18639 0.0559440559440559 0.700296345695943 0.892972767764025 0.999999999554324 GO:0031490 chromatin DNA binding 7/1489 128/18639 0.0546875 0.684567033243788 0.894162396743907 0.999999999554324 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/1489 27/18639 0.037037037037037 0.463622117752406 0.894558842915302 0.999999999554324 GO:0005104 fibroblast growth factor receptor binding 1/1489 27/18639 0.037037037037037 0.463622117752406 0.894558842915302 0.999999999554324 GO:0005385 zinc ion transmembrane transporter activity 1/1489 27/18639 0.037037037037037 0.463622117752406 0.894558842915302 0.999999999554324 GO:0008320 protein transmembrane transporter activity 1/1489 27/18639 0.037037037037037 0.463622117752406 0.894558842915302 0.999999999554324 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/1489 27/18639 0.037037037037037 0.463622117752406 0.894558842915302 0.999999999554324 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/1489 27/18639 0.037037037037037 0.463622117752406 0.894558842915302 0.999999999554324 GO:0004536 DNA nuclease activity 3/1489 64/18639 0.046875 0.58677174278039 0.894872419218575 0.999999999554324 GO:0099095 ligand-gated monoatomic anion channel activity 2/1489 47/18639 0.0425531914893617 0.532672220396382 0.898791672253131 0.999999999554324 GO:0140359 ABC-type transporter activity 2/1489 47/18639 0.0425531914893617 0.532672220396382 0.898791672253131 0.999999999554324 GO:0005242 inward rectifier potassium channel activity 1/1489 28/18639 0.0357142857142857 0.447064184975535 0.902994362091055 0.999999999554324 GO:0046966 nuclear thyroid hormone receptor binding 1/1489 28/18639 0.0357142857142857 0.447064184975535 0.902994362091055 0.999999999554324 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 7/1489 132/18639 0.053030303030303 0.663822577690946 0.910700852036017 0.999999999554324 GO:0016417 S-acyltransferase activity 1/1489 29/18639 0.0344827586206897 0.431648178597068 0.910755438596693 0.999999999554324 GO:0051861 glycolipid binding 1/1489 29/18639 0.0344827586206897 0.431648178597068 0.910755438596693 0.999999999554324 GO:0004527 exonuclease activity 4/1489 84/18639 0.0476190476190476 0.59608557996738 0.911539557744398 0.999999999554324 GO:0003777 microtubule motor activity 3/1489 68/18639 0.0441176470588235 0.552255757910955 0.916670679840387 0.999999999554324 GO:1990841 promoter-specific chromatin binding 3/1489 68/18639 0.0441176470588235 0.552255757910955 0.916670679840387 0.999999999554324 GO:0016853 isomerase activity 10/1489 180/18639 0.0555555555555556 0.69543317662861 0.917404187823204 0.999999999554324 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/1489 30/18639 0.0333333333333333 0.417259905977166 0.91789596261225 0.999999999554324 GO:0022839 monoatomic ion-gated channel activity 1/1489 30/18639 0.0333333333333333 0.417259905977166 0.91789596261225 0.999999999554324 GO:0035925 mRNA 3'-UTR AU-rich region binding 1/1489 30/18639 0.0333333333333333 0.417259905977166 0.91789596261225 0.999999999554324 GO:0051721 protein phosphatase 2A binding 1/1489 30/18639 0.0333333333333333 0.417259905977166 0.91789596261225 0.999999999554324 GO:0098918 structural constituent of synapse 1/1489 30/18639 0.0333333333333333 0.417259905977166 0.91789596261225 0.999999999554324 GO:0002039 p53 binding 3/1489 69/18639 0.0434782608695652 0.544252051274564 0.92143473100524 0.999999999554324 GO:0016874 ligase activity 9/1489 167/18639 0.0538922155688623 0.674611824034939 0.924398379103295 0.999999999554324 GO:0005184 neuropeptide hormone activity 1/1489 31/18639 0.032258064516129 0.403799909010161 0.924465520980263 0.999999999554324 GO:0008327 methyl-CpG binding 1/1489 31/18639 0.032258064516129 0.403799909010161 0.924465520980263 0.999999999554324 GO:0016411 acylglycerol O-acyltransferase activity 1/1489 31/18639 0.032258064516129 0.403799909010161 0.924465520980263 0.999999999554324 GO:0072349 modified amino acid transmembrane transporter activity 1/1489 31/18639 0.032258064516129 0.403799909010161 0.924465520980263 0.999999999554324 GO:0160041 neuropeptide activity 1/1489 32/18639 0.03125 0.391181161853593 0.930509740630972 0.999999999554324 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 6/1489 122/18639 0.0491803278688525 0.615629369474507 0.931508715116604 0.999999999554324 GO:0004497 monooxygenase activity 5/1489 106/18639 0.0471698113207547 0.590462131099763 0.932838101596849 0.999999999554324 GO:0008017 microtubule binding 16/1489 276/18639 0.0579710144927536 0.725669401699419 0.934124148790504 0.999999999554324 GO:0140767 enzyme-substrate adaptor activity 7/1489 139/18639 0.0503597122302158 0.63039266370651 0.934325124512816 0.999999999554324 GO:0042923 neuropeptide binding 1/1489 33/18639 0.0303030303030303 0.379327187251969 0.93607060461767 0.999999999554324 GO:0140463 chromatin-protein adaptor activity 2/1489 54/18639 0.037037037037037 0.463622117752406 0.936811324642589 0.999999999554324 GO:0019787 ubiquitin-like protein transferase activity 30/1489 479/18639 0.0626304801670146 0.783995647973798 0.936888770703564 0.999999999554324 GO:0004521 RNA endonuclease activity 3/1489 73/18639 0.0410958904109589 0.514430021067739 0.938098399504087 0.999999999554324 GO:0008374 O-acyltransferase activity 2/1489 55/18639 0.0363636363636364 0.455192624702363 0.940983380325569 0.999999999554324 GO:0008376 acetylgalactosaminyltransferase activity 1/1489 34/18639 0.0294117647058824 0.36817050527397 0.941186742945321 0.999999999554324 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/1489 34/18639 0.0294117647058824 0.36817050527397 0.941186742945321 0.999999999554324 GO:0016831 carboxy-lyase activity 1/1489 34/18639 0.0294117647058824 0.36817050527397 0.941186742945321 0.999999999554324 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/1489 34/18639 0.0294117647058824 0.36817050527397 0.941186742945321 0.999999999554324 GO:0016755 aminoacyltransferase activity 31/1489 496/18639 0.0625 0.782362323707186 0.941341629878391 0.999999999554324 GO:0044183 protein folding chaperone 3/1489 75/18639 0.04 0.500711887172599 0.945144515001155 0.999999999554324 GO:0004519 endonuclease activity 6/1489 127/18639 0.047244094488189 0.591391992723542 0.946044732470836 0.999999999554324 GO:0015631 tubulin binding 23/1489 385/18639 0.0597402597402597 0.747816454868167 0.946550519615944 0.999999999554324 GO:0000993 RNA polymerase II complex binding 1/1489 36/18639 0.0277777777777778 0.347716588314305 0.950224181840015 0.999999999554324 GO:0004033 aldo-keto reductase (NADPH) activity 1/1489 36/18639 0.0277777777777778 0.347716588314305 0.950224181840015 0.999999999554324 GO:0004190 aspartic-type endopeptidase activity 1/1489 36/18639 0.0277777777777778 0.347716588314305 0.950224181840015 0.999999999554324 GO:0003724 RNA helicase activity 3/1489 77/18639 0.038961038961039 0.487706383609674 0.951439057042093 0.999999999554324 GO:0070001 aspartic-type peptidase activity 1/1489 37/18639 0.027027027027027 0.338318842684189 0.95420828081546 0.999999999554324 GO:0008186 ATP-dependent activity, acting on RNA 3/1489 79/18639 0.0379746835443038 0.475359386556265 0.957054087942391 0.999999999554324 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 9/1489 181/18639 0.0497237569060773 0.622431903943839 0.957745717247358 0.999999999554324 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 2/1489 60/18639 0.0333333333333333 0.417259905977166 0.958197430264234 0.999999999554324 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 2/1489 60/18639 0.0333333333333333 0.417259905977166 0.958197430264234 0.999999999554324 GO:0005249 voltage-gated potassium channel activity 4/1489 98/18639 0.0408163265306122 0.510930497114897 0.958928946541825 0.999999999554324 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/1489 40/18639 0.025 0.312944929482874 0.964348288375573 0.999999999554324 GO:0008135 translation factor activity, RNA binding 3/1489 83/18639 0.036144578313253 0.452450500457168 0.966506247679306 0.999999999554324 GO:0180051 translation factor activity 3/1489 84/18639 0.0357142857142857 0.447064184975535 0.968542051010229 0.999999999554324 GO:0043175 RNA polymerase core enzyme binding 1/1489 42/18639 0.0238095238095238 0.29804278998369 0.969828341530643 0.999999999554324 GO:0120013 lipid transfer activity 2/1489 65/18639 0.0307692307692308 0.385162990132769 0.970538604504025 0.999999999554324 GO:0004842 ubiquitin-protein transferase activity 26/1489 449/18639 0.0579064587973274 0.724861306597304 0.97074693163725 0.999999999554324 GO:0050660 flavin adenine dinucleotide binding 3/1489 86/18639 0.0348837209302326 0.436667343464476 0.972267808501219 0.999999999554324 GO:0042054 histone methyltransferase activity 2/1489 67/18639 0.0298507462686567 0.373665587442238 0.97441852208142 0.999999999554324 GO:0004252 serine-type endopeptidase activity 8/1489 176/18639 0.0454545454545455 0.568990780877954 0.974595168507272 0.999999999554324 GO:0004518 nuclease activity 10/1489 209/18639 0.0478468899521531 0.598937664082056 0.974777260455473 0.999999999554324 GO:0016279 protein-lysine N-methyltransferase activity 2/1489 69/18639 0.0289855072463768 0.362834700849709 0.977802299252681 0.999999999554324 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/1489 46/18639 0.0217391304347826 0.272126025637282 0.978392108606364 0.999999999554324 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/1489 46/18639 0.0217391304347826 0.272126025637282 0.978392108606364 0.999999999554324 GO:0016278 lysine N-methyltransferase activity 2/1489 70/18639 0.0285714285714286 0.357651347980428 0.97932741434719 0.999999999554324 GO:0061749 forked DNA-dependent helicase activity 1/1489 47/18639 0.0212765957446809 0.266336110198191 0.980122552874913 0.999999999554324 GO:0140938 histone H3 methyltransferase activity 1/1489 47/18639 0.0212765957446809 0.266336110198191 0.980122552874913 0.999999999554324 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/1489 47/18639 0.0212765957446809 0.266336110198191 0.980122552874913 0.999999999554324 GO:0008188 neuropeptide receptor activity 1/1489 48/18639 0.0208333333333333 0.260787441235729 0.981714502034189 0.999999999554324 GO:0009378 four-way junction helicase activity 1/1489 48/18639 0.0208333333333333 0.260787441235729 0.981714502034189 0.999999999554324 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/1489 48/18639 0.0208333333333333 0.260787441235729 0.981714502034189 0.999999999554324 GO:0036121 double-stranded DNA helicase activity 1/1489 48/18639 0.0208333333333333 0.260787441235729 0.981714502034189 0.999999999554324 GO:0043138 3'-5' DNA helicase activity 1/1489 48/18639 0.0208333333333333 0.260787441235729 0.981714502034189 0.999999999554324 GO:0008276 protein methyltransferase activity 3/1489 95/18639 0.0315789473684211 0.395298858294157 0.984427794324114 0.999999999554324 GO:0015605 organophosphate ester transmembrane transporter activity 1/1489 50/18639 0.02 0.2503559435863 0.984526339629596 0.999999999554324 GO:0005048 signal sequence binding 1/1489 51/18639 0.0196078431372549 0.24544700351598 0.985765797389106 0.999999999554324 GO:0016779 nucleotidyltransferase activity 5/1489 136/18639 0.0367647058823529 0.460213131592462 0.986640909591665 0.999999999554324 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/1489 52/18639 0.0192307692307692 0.24072686883298 0.986906034514543 0.999999999554324 GO:0008170 N-methyltransferase activity 3/1489 98/18639 0.0306122448979592 0.383197872836173 0.987195041792986 0.999999999554324 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/1489 53/18639 0.0188679245283019 0.236184852439905 0.987954988870159 0.999999999554324 GO:0003823 antigen binding 7/1489 174/18639 0.0402298850574713 0.50358954169658 0.987974141180996 0.999999999554324 GO:0004540 RNA nuclease activity 4/1489 121/18639 0.0330578512396694 0.413811477002148 0.989442848706193 0.999999999554324 GO:0000049 tRNA binding 2/1489 80/18639 0.025 0.312944929482874 0.989935340816911 0.999999999554324 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/1489 57/18639 0.0175438596491228 0.219610476830087 0.991375559917691 0.999999999554324 GO:0008408 3'-5' exonuclease activity 1/1489 58/18639 0.0172413793103448 0.215824089298534 0.99206664759838 0.999999999554324 GO:0017116 single-stranded DNA helicase activity 1/1489 58/18639 0.0172413793103448 0.215824089298534 0.99206664759838 0.999999999554324 GO:0031593 polyubiquitin modification-dependent protein binding 1/1489 59/18639 0.0169491525423729 0.212166053886695 0.992702391730882 0.999999999554324 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/1489 60/18639 0.0166666666666667 0.208629952988583 0.993287221586248 0.999999999554324 GO:0016887 ATP hydrolysis activity 21/1489 417/18639 0.0503597122302158 0.63039266370651 0.993356052691107 0.999999999554324 GO:0000510 H3-H4 histone complex chaperone activity 5/1489 151/18639 0.033112582781457 0.414496595341556 0.994416788446561 0.999999999554324 GO:0140584 chromatin extrusion motor activity 5/1489 151/18639 0.033112582781457 0.414496595341556 0.994416788446561 0.999999999554324 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 5/1489 151/18639 0.033112582781457 0.414496595341556 0.994416788446561 0.999999999554324 GO:0140849 ATP-dependent H2AZ histone chaperone activity 5/1489 151/18639 0.033112582781457 0.414496595341556 0.994416788446561 0.999999999554324 GO:0015616 DNA translocase activity 5/1489 152/18639 0.0328947368421053 0.411769644056414 0.994738931715227 0.999999999554324 GO:0140674 ATP-dependent histone chaperone activity 5/1489 152/18639 0.0328947368421053 0.411769644056414 0.994738931715227 0.999999999554324 GO:0061775 cohesin loader activity 5/1489 153/18639 0.0326797385620915 0.4090783391933 0.995043223373632 0.999999999554324 GO:0008094 ATP-dependent activity, acting on DNA 8/1489 210/18639 0.0380952380952381 0.476868463973904 0.995346113222645 0.999999999554324 GO:0043021 ribonucleoprotein complex binding 6/1489 177/18639 0.0338983050847458 0.424332107773389 0.996251448478296 0.999999999554324 GO:0140658 ATP-dependent chromatin remodeler activity 5/1489 158/18639 0.0316455696202532 0.396132822130221 0.996328154970577 0.999999999554324 GO:0016410 N-acyltransferase activity 2/1489 94/18639 0.0212765957446809 0.266336110198191 0.9964001061655 0.999999999554324 GO:0003689 DNA clamp loader activity 5/1489 160/18639 0.03125 0.391181161853593 0.996746645639672 0.999999999554324 GO:0016407 acetyltransferase activity 2/1489 96/18639 0.0208333333333333 0.260787441235729 0.996896917862417 0.999999999554324 GO:0051082 unfolded protein binding 3/1489 121/18639 0.0247933884297521 0.310358607751611 0.9972685033718 0.999999999554324 GO:0140713 histone chaperone activity 5/1489 164/18639 0.0304878048780488 0.381640157905944 0.997450107532411 0.999999999554324 GO:0043130 ubiquitin binding 2/1489 100/18639 0.02 0.2503559435863 0.997696806021331 0.999999999554324 GO:0003678 DNA helicase activity 1/1489 74/18639 0.0135135135135135 0.169159421342094 0.997916502060571 0.999999999554324 GO:0035064 methylated histone binding 1/1489 74/18639 0.0135135135135135 0.169159421342094 0.997916502060571 0.999999999554324 GO:0003730 mRNA 3'-UTR binding 10/1489 262/18639 0.0381679389312977 0.477778518294465 0.997986354208032 0.999999999554324 GO:0140597 protein carrier chaperone 6/1489 188/18639 0.0319148936170213 0.399504165297286 0.998024975292516 0.999999999554324 GO:0140034 methylation-dependent protein binding 1/1489 76/18639 0.0131578947368421 0.164707857622565 0.998237320229007 0.999999999554324 GO:0042393 histone binding 9/1489 247/18639 0.0364372469635627 0.456114067262489 0.998284503264204 0.999999999554324 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 8/1489 229/18639 0.0349344978165939 0.437302958229344 0.998325996574804 0.999999999554324 GO:0140030 modification-dependent protein binding 5/1489 173/18639 0.0289017341040462 0.361786045644942 0.998537166535569 0.999999999554324 GO:0016741 transferase activity, transferring one-carbon groups 7/1489 215/18639 0.0325581395348837 0.407556187233511 0.998732797518937 0.999999999554324 GO:0004386 helicase activity 4/1489 155/18639 0.0258064516129032 0.323039927208128 0.998790657104112 0.999999999554324 GO:0043022 ribosome binding 2/1489 112/18639 0.0178571428571429 0.223532092487767 0.999065583916942 0.999999999554324 GO:0008168 methyltransferase activity 6/1489 204/18639 0.0294117647058824 0.36817050527397 0.999242949322899 0.999999999554324 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 4/1489 167/18639 0.0239520958083832 0.299827477348862 0.999455649312891 0.999999999554324 GO:0032182 ubiquitin-like protein binding 2/1489 120/18639 0.0166666666666667 0.208629952988583 0.999490847160081 0.999999999554324 GO:0140097 catalytic activity, acting on DNA 12/1489 336/18639 0.0357142857142857 0.447064184975535 0.999717635560702 0.999999999554324 GO:0004843 cysteine-type deubiquitinase activity 1/1489 108/18639 0.00925925925925926 0.115905529438102 0.999878898972231 0.999999999554324 GO:0101005 deubiquitinase activity 1/1489 115/18639 0.00869565217391304 0.108850410254913 0.999932631519516 0.999999999554324 GO:0019783 ubiquitin-like protein peptidase activity 1/1489 127/18639 0.0078740157480315 0.0985653321205904 0.999975361751702 0.999999999554324 GO:0045182 translation regulator activity 7/1489 356/18639 0.0196629213483146 0.246136461391025 0.999999840752743 0.999999999554324 GO:0140098 catalytic activity, acting on RNA 7/1489 387/18639 0.0180878552971576 0.226420104018617 0.999999981232072 0.999999999554324 GO:0030371 translation repressor activity 3/1489 329/18639 0.00911854103343465 0.114144047227796 0.999999999554324 0.999999999554324