ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	76/3388	175/18639	0.434285714285714	2.38921234609546	7.85115616358985e-15	1.01122891387037e-11
GO:0016853	isomerase activity	69/3388	180/18639	0.383333333333333	2.10889905548996	1.38629320755039e-10	7.21292867257935e-08
GO:0043021	ribonucleoprotein complex binding	68/3388	177/18639	0.384180790960452	2.11356132311448	1.68002997032128e-10	7.21292867257935e-08
GO:0009055	electron transfer activity	50/3388	116/18639	0.431034482758621	2.37132577453894	4.14354950577887e-10	1.3342229408608e-07
GO:0022853	active monoatomic ion transmembrane transporter activity	49/3388	118/18639	0.415254237288136	2.28451113601345	2.85372002698421e-09	7.35118278951133e-07
GO:0043022	ribosome binding	45/3388	112/18639	0.401785714285714	2.21041438269523	4.13091467753406e-08	8.86769684110644e-06
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	29/3388	60/18639	0.483333333333333	2.659046635183	9.32919585403661e-08	1.71657203714274e-05
GO:0003713	transcription coactivator activity	81/3388	256/18639	0.31640625	1.74070132637249	1.18138230547148e-07	1.90202551180909e-05
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	31/3388	68/18639	0.455882352941176	2.50802573095354	1.82736598248347e-07	2.61516376159857e-05
GO:0019843	rRNA binding	30/3388	65/18639	0.461538461538462	2.53914267550631	2.05187719138176e-07	2.64281782249971e-05
GO:0015078	proton transmembrane transporter activity	62/3388	185/18639	0.335135135135135	1.84373783464693	3.84330929533214e-07	4.50016579307981e-05
GO:0140104	molecular carrier activity	77/3388	249/18639	0.309236947791165	1.7012595837897	6.65926031430714e-07	7.14760607068967e-05
GO:0060590	ATPase regulator activity	24/3388	49/18639	0.489795918367347	2.69460039033323	8.71907928316077e-07	8.63859547439314e-05
GO:0015036	disulfide oxidoreductase activity	21/3388	40/18639	0.525	2.88827479338843	9.74975616915062e-07	8.96977567561857e-05
GO:0015399	primary active transmembrane transporter activity	56/3388	166/18639	0.337349397590361	1.8559195459524	1.08613818262202e-06	9.32630652811444e-05
GO:0051087	protein-folding chaperone binding	47/3388	134/18639	0.350746268656716	1.92962210787855	2.28351981510854e-06	0.000182925696905067
GO:0003712	transcription coregulator activity	131/3388	495/18639	0.264646464646465	1.45594611999571	2.41439196225632e-06	0.000182925696905067
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	26/3388	58/18639	0.448275862068966	2.4661788055205	2.60672023176751e-06	0.000186525314362031
GO:0016866	intramolecular transferase activity	16/3388	28/18639	0.571428571428571	3.14370045538877	4.50235649313069e-06	0.000305212377008017
GO:0016860	intramolecular oxidoreductase activity	24/3388	53/18639	0.452830188679245	2.49123432313827	5.05705020342885e-06	0.000311814805675216
GO:0044389	ubiquitin-like protein ligase binding	91/3388	322/18639	0.282608695652174	1.55476489913249	5.08393704905243e-06	0.000311814805675216
GO:0140098	catalytic activity, acting on RNA	105/3388	387/18639	0.271317829457364	1.49264847203536	7.38842513062223e-06	0.000432558707647338
GO:0000287	magnesium ion binding	69/3388	230/18639	0.3	1.6504427390791	7.92789004227116e-06	0.000443961842367185
GO:0051082	unfolded protein binding	42/3388	121/18639	0.347107438016529	1.90960316918243	1.03726527719893e-05	0.000556665698763426
GO:0031625	ubiquitin protein ligase binding	84/3388	302/18639	0.278145695364238	1.53021181106672	2.19691521712584e-05	0.00113185071986323
GO:0015035	protein-disulfide reductase activity	17/3388	34/18639	0.5	2.75073789846517	2.45080659060778e-05	0.00121409188027032
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	23/3388	54/18639	0.425925925925926	2.34322117276663	2.7108602204774e-05	0.00129318072739811
GO:0008135	translation factor activity, RNA binding	31/3388	83/18639	0.373493975903614	2.05476806873302	2.87069971087409e-05	0.00132052186700208
GO:0180051	translation factor activity	31/3388	84/18639	0.369047619047619	2.03030654410525	3.76473011562534e-05	0.00167205944445705
GO:0031593	polyubiquitin modification-dependent protein binding	24/3388	59/18639	0.406779661016949	2.23788845976827	4.54327802228529e-05	0.00186071784140144
GO:0004129	cytochrome-c oxidase activity	10/3388	15/18639	0.666666666666667	3.66765053128689	4.76736714023662e-05	0.00186071784140144
GO:0031386	protein tag activity	10/3388	15/18639	0.666666666666667	3.66765053128689	4.76736714023662e-05	0.00186071784140144
GO:0141047	molecular tag activity	10/3388	15/18639	0.666666666666667	3.66765053128689	4.76736714023662e-05	0.00186071784140144
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	18/3388	39/18639	0.461538461538462	2.53914267550631	5.57412721247256e-05	0.00211161054401902
GO:0003746	translation elongation factor activity	11/3388	18/18639	0.611111111111111	3.36201298701299	6.33537150105697e-05	0.00233141671238896
GO:0016675	oxidoreductase activity, acting on a heme group of donors	10/3388	16/18639	0.625	3.43842237308146	0.000106349891994683	0.00380496280247642
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	50/3388	167/18639	0.29940119760479	1.64714844219471	0.00013974916344574	0.00486478168967872
GO:0003924	GTPase activity	87/3388	331/18639	0.262839879154079	1.44600723363426	0.000144823935456939	0.004908769180751
GO:0008173	RNA methyltransferase activity	25/3388	67/18639	0.373134328358209	2.05278947646655	0.000168153951569463	0.00555339204157611
GO:0016859	cis-trans isomerase activity	18/3388	42/18639	0.428571428571429	2.35777534154158	0.000181450768715086	0.00584271475262578
GO:0008168	methyltransferase activity	58/3388	204/18639	0.284313725490196	1.56414507951941	0.000205030791246345	0.00644096729573885
GO:0032977	membrane insertase activity	10/3388	17/18639	0.588235294117647	3.23616223348844	0.000216139658311893	0.00662828285489805
GO:0031418	L-ascorbic acid binding	11/3388	20/18639	0.55	3.02581168831169	0.000233492665316054	0.00683228964522183
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	16/3388	36/18639	0.444444444444444	2.44510035419126	0.000247517762520719	0.00683228964522183
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	16/3388	36/18639	0.444444444444444	2.44510035419126	0.000247517762520719	0.00683228964522183
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	16/3388	36/18639	0.444444444444444	2.44510035419126	0.000247517762520719	0.00683228964522183
GO:0140597	protein carrier chaperone	54/3388	188/18639	0.287234042553192	1.58021113316084	0.000251903683134801	0.00683228964522183
GO:0005525	GTP binding	96/3388	378/18639	0.253968253968254	1.39720020239501	0.000259545655303173	0.00683228964522183
GO:0016651	oxidoreductase activity, acting on NAD(P)H	30/3388	88/18639	0.340909090909091	1.87550311258989	0.000259924062589961	0.00683228964522183
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	15/3388	33/18639	0.454545454545455	2.50067081678652	0.0002848231153614	0.00733704345170966
GO:0031543	peptidyl-proline dioxygenase activity	8/3388	12/18639	0.666666666666667	3.66765053128689	0.000290766630754794	0.00734328275317991
GO:0140030	modification-dependent protein binding	50/3388	173/18639	0.289017341040462	1.59002190662727	0.000356406576032522	0.00870765947995658
GO:0001671	ATPase activator activity	13/3388	27/18639	0.481481481481481	2.64885871704053	0.000360126607862529	0.00870765947995658
GO:0003954	NADH dehydrogenase activity	18/3388	44/18639	0.409090909090909	2.25060373510787	0.000365072680060291	0.00870765947995658
GO:0042625	ATPase-coupled ion transmembrane transporter activity	12/3388	24/18639	0.5	2.75073789846517	0.000391205538104215	0.00878122900029215
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	12/3388	24/18639	0.5	2.75073789846517	0.000391205538104215	0.00878122900029215
GO:0046961	proton-transporting ATPase activity, rotational mechanism	12/3388	24/18639	0.5	2.75073789846517	0.000391205538104215	0.00878122900029215
GO:0031072	heat shock protein binding	40/3388	131/18639	0.305343511450382	1.679839937994	0.000398186110485014	0.00878122900029215
GO:0016209	antioxidant activity	29/3388	86/18639	0.337209302325581	1.85514881524395	0.00040224573836742	0.00878122900029215
GO:0047429	nucleoside triphosphate diphosphatase activity	7/3388	10/18639	0.7	3.85103305785124	0.000466750943509475	0.0100195869206701
GO:0016741	transferase activity, transferring one-carbon groups	59/3388	215/18639	0.274418604651163	1.50970731171577	0.000498948593450999	0.0105351768584408
GO:0004527	exonuclease activity	28/3388	84/18639	0.333333333333333	1.83382526564345	0.000619707162746012	0.0128739165422075
GO:0009982	pseudouridine synthase activity	8/3388	13/18639	0.615384615384615	3.38552356734175	0.000635284115554971	0.0129695716897089
GO:0140097	catalytic activity, acting on DNA	85/3388	336/18639	0.25297619047619	1.3917423891044	0.000644450767190506	0.0129695716897089
GO:0016757	glycosyltransferase activity	70/3388	267/18639	0.262172284644195	1.44233447859597	0.000659774279961283	0.0130736811167713
GO:0030515	snoRNA binding	14/3388	32/18639	0.4375	2.40689566115702	0.000728543969533931	0.0140054422799956
GO:0140142	nucleocytoplasmic carrier activity	14/3388	32/18639	0.4375	2.40689566115702	0.000728543969533931	0.0140054422799956
GO:0051540	metal cluster binding	26/3388	77/18639	0.337662337662338	1.85764117818427	0.000766388713879812	0.0145163038746647
GO:0050660	flavin adenine dinucleotide binding	28/3388	86/18639	0.325581395348837	1.79117816644244	0.000941680351688098	0.0174987531751415
GO:0031491	nucleosome binding	25/3388	74/18639	0.337837837837838	1.85860668815214	0.000951019194301166	0.0174987531751415
GO:0004177	aminopeptidase activity	16/3388	40/18639	0.4	2.20059031877214	0.00102333509888733	0.0185641634840407
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	7/3388	11/18639	0.636363636363636	3.50093914350113	0.00108162327935147	0.0193490386639542
GO:0016530	metallochaperone activity	8/3388	14/18639	0.571428571428571	3.14370045538877	0.0012462819720676	0.0212770164902894
GO:0004549	tRNA-specific ribonuclease activity	9/3388	17/18639	0.529411764705882	2.91254601013959	0.00126866253348104	0.0212770164902894
GO:0004659	prenyltransferase activity	9/3388	17/18639	0.529411764705882	2.91254601013959	0.00126866253348104	0.0212770164902894
GO:0019001	guanyl nucleotide binding	97/3388	400/18639	0.2425	1.33410788075561	0.00127199555104991	0.0212770164902894
GO:0032561	guanyl ribonucleotide binding	97/3388	400/18639	0.2425	1.33410788075561	0.00127199555104991	0.0212770164902894
GO:0045296	cadherin binding	83/3388	334/18639	0.248502994011976	1.36713320702161	0.00130384104328971	0.0215300931250917
GO:0008137	NADH dehydrogenase (ubiquinone) activity	16/3388	41/18639	0.390243902439024	2.14691738416794	0.00139821489837871	0.0226393636907147
GO:0001098	basal transcription machinery binding	21/3388	60/18639	0.35	1.92551652892562	0.00142374880353097	0.0226393636907147
GO:0001099	basal RNA polymerase II transcription machinery binding	21/3388	60/18639	0.35	1.92551652892562	0.00142374880353097	0.0226393636907147
GO:0051536	iron-sulfur cluster binding	25/3388	76/18639	0.328947368421053	1.80969598583235	0.00146399508155391	0.0229954349395298
GO:0008175	tRNA methyltransferase activity	14/3388	34/18639	0.411764705882353	2.26531356344191	0.00149713997351324	0.0232327263359645
GO:0016763	pentosyltransferase activity	18/3388	49/18639	0.36734693877551	2.02095029274992	0.00163283119145993	0.0250367449357189
GO:0140296	general transcription initiation factor binding	19/3388	53/18639	0.358490566037736	1.97222717248446	0.00171183861049003	0.0259393897683665
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	21/3388	61/18639	0.344262295081967	1.89395068418913	0.00180468455500332	0.0270282989167939
GO:0061659	ubiquitin-like protein ligase activity	90/3388	372/18639	0.241935483870968	1.33100220893476	0.00200095607810472	0.0296233497540101
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	9/3388	18/18639	0.5	2.75073789846517	0.00213020297952353	0.029793786217832
GO:0032182	ubiquitin-like protein binding	35/3388	120/18639	0.291666666666667	1.60459710743802	0.00214508735952184	0.029793786217832
GO:0003995	acyl-CoA dehydrogenase activity	7/3388	12/18639	0.583333333333333	3.20919421487603	0.00218882258738683	0.029793786217832
GO:0004526	ribonuclease P activity	7/3388	12/18639	0.583333333333333	3.20919421487603	0.00218882258738683	0.029793786217832
GO:0005049	nuclear export signal receptor activity	7/3388	12/18639	0.583333333333333	3.20919421487603	0.00218882258738683	0.029793786217832
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	7/3388	12/18639	0.583333333333333	3.20919421487603	0.00218882258738683	0.029793786217832
GO:0017069	snRNA binding	19/3388	54/18639	0.351851851851852	1.93570444706808	0.00219752305178109	0.029793786217832
GO:0050661	NADP binding	19/3388	54/18639	0.351851851851852	1.93570444706808	0.00219752305178109	0.029793786217832
GO:0042809	nuclear vitamin D receptor binding	8/3388	15/18639	0.533333333333333	2.93412042502952	0.00224651416777606	0.0298300025576862
GO:0055105	ubiquitin-protein transferase inhibitor activity	8/3388	15/18639	0.533333333333333	2.93412042502952	0.00224651416777606	0.0298300025576862
GO:0019003	GDP binding	24/3388	75/18639	0.32	1.76047225501771	0.00273027298958307	0.0355542739092435
GO:0003743	translation initiation factor activity	18/3388	51/18639	0.352941176470588	1.94169734009306	0.00273282074302415	0.0355542739092435
GO:0005484	SNAP receptor activity	14/3388	36/18639	0.388888888888889	2.13946280991736	0.00284488641127121	0.0366421369771731
GO:0019787	ubiquitin-like protein transferase activity	111/3388	479/18639	0.231732776617954	1.27487226191914	0.00308273160570863	0.0390245464237973
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	15/3388	40/18639	0.375	2.06305342384888	0.00309045321058022	0.0390245464237973
GO:0002020	protease binding	38/3388	136/18639	0.279411764705882	1.53717706090701	0.0032754874746536	0.0409594938578042
GO:0003756	protein disulfide isomerase activity	9/3388	19/18639	0.473684210526316	2.60596221959858	0.00339956977300634	0.0413079798833223
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	9/3388	19/18639	0.473684210526316	2.60596221959858	0.00339956977300634	0.0413079798833223
GO:0046527	glucosyltransferase activity	9/3388	19/18639	0.473684210526316	2.60596221959858	0.00339956977300634	0.0413079798833223
GO:0004518	nuclease activity	54/3388	209/18639	0.258373205741627	1.42143393796286	0.00356003363788482	0.0428534890242584
GO:0070006	metalloaminopeptidase activity	11/3388	26/18639	0.423076923076923	2.32754745254745	0.0036876877198491	0.0439246685072203
GO:0001094	TFIID-class transcription factor complex binding	6/3388	10/18639	0.6	3.30088547815821	0.00385363939543159	0.0439246685072203
GO:0008239	dipeptidyl-peptidase activity	6/3388	10/18639	0.6	3.30088547815821	0.00385363939543159	0.0439246685072203
GO:0016868	intramolecular phosphotransferase activity	6/3388	10/18639	0.6	3.30088547815821	0.00385363939543159	0.0439246685072203
GO:0033204	ribonuclease P RNA binding	6/3388	10/18639	0.6	3.30088547815821	0.00385363939543159	0.0439246685072203
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	6/3388	10/18639	0.6	3.30088547815821	0.00385363939543159	0.0439246685072203
GO:0019104	DNA N-glycosylase activity	7/3388	13/18639	0.538461538461538	2.96233312142403	0.00400128413785732	0.0452074909610547
GO:0051020	GTPase binding	76/3388	315/18639	0.241269841269841	1.32734019227526	0.00457001304069844	0.0511841460558225
GO:0140674	ATP-dependent histone chaperone activity	41/3388	152/18639	0.269736842105263	1.48395070838253	0.00461381883301768	0.0512292987666101
GO:0140101	catalytic activity, acting on a tRNA	38/3388	139/18639	0.273381294964029	1.50400057757808	0.00489132058259591	0.0538463325673806
GO:0042162	telomeric DNA binding	14/3388	38/18639	0.368421052631579	2.02685950413223	0.00505458536965863	0.055172084373901
GO:0000339	RNA cap binding	9/3388	20/18639	0.45	2.47566410861865	0.00519422833510945	0.0556343177520104
GO:0043024	ribosomal small subunit binding	9/3388	20/18639	0.45	2.47566410861865	0.00519422833510945	0.0556343177520104
GO:0019903	protein phosphatase binding	39/3388	144/18639	0.270833333333333	1.4899830283353	0.00522651587577116	0.0556343177520104
GO:0051879	Hsp90 protein binding	15/3388	42/18639	0.357142857142857	1.96481278461798	0.00528038650911606	0.0557470313421434
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	34/3388	122/18639	0.278688524590164	1.53319817291501	0.00543847247992036	0.0569208995207036
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	18/3388	54/18639	0.333333333333333	1.83382526564345	0.00548691821143302	0.0569208995207036
GO:0140658	ATP-dependent chromatin remodeler activity	42/3388	158/18639	0.265822784810127	1.46241761690553	0.0055241556211863	0.0569208995207036
GO:0016407	acetyltransferase activity	28/3388	96/18639	0.291666666666667	1.60459710743802	0.00564082584837023	0.0575659896891803
GO:0140297	DNA-binding transcription factor binding	111/3388	488/18639	0.227459016393443	1.25136027348211	0.00567614960444557	0.0575659896891803
GO:0032183	SUMO binding	8/3388	17/18639	0.470588235294118	2.58892978679075	0.00601529158265361	0.0605288715504519
GO:0042393	histone binding	61/3388	247/18639	0.246963562753036	1.35866406320952	0.00607276946413951	0.0606335431768348
GO:0001091	RNA polymerase II general transcription initiation factor binding	10/3388	24/18639	0.416666666666667	2.29228158205431	0.0063342073223162	0.062605012655377
GO:0061630	ubiquitin protein ligase activity	83/3388	353/18639	0.235127478753541	1.29354813355586	0.00645967668092114	0.062605012655377
GO:0051117	ATPase binding	25/3388	84/18639	0.297619047619048	1.63734398718165	0.00651120309589526	0.062605012655377
GO:0140713	histone chaperone activity	43/3388	164/18639	0.26219512195122	1.44246011748783	0.00653804663221612	0.062605012655377
GO:0005507	copper ion binding	20/3388	63/18639	0.317460317460317	1.74650025299376	0.00654026086145058	0.062605012655377
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	57/3388	229/18639	0.248908296943231	1.36936297128834	0.00656758444508501	0.062605012655377
GO:0008174	mRNA methyltransferase activity	7/3388	14/18639	0.5	2.75073789846517	0.00675628630364706	0.062605012655377
GO:0008474	palmitoyl-(protein) hydrolase activity	7/3388	14/18639	0.5	2.75073789846517	0.00675628630364706	0.062605012655377
GO:0030983	mismatched DNA binding	7/3388	14/18639	0.5	2.75073789846517	0.00675628630364706	0.062605012655377
GO:0098599	palmitoyl hydrolase activity	7/3388	14/18639	0.5	2.75073789846517	0.00675628630364706	0.062605012655377
GO:0016758	hexosyltransferase activity	50/3388	197/18639	0.253807106598985	1.39631365404323	0.00705850603783215	0.0632847732514
GO:0000510	H3-H4 histone complex chaperone activity	40/3388	151/18639	0.264900662251656	1.4573445819683	0.00707531626413168	0.0632847732514
GO:0140584	chromatin extrusion motor activity	40/3388	151/18639	0.264900662251656	1.4573445819683	0.00707531626413168	0.0632847732514
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	40/3388	151/18639	0.264900662251656	1.4573445819683	0.00707531626413168	0.0632847732514
GO:0140849	ATP-dependent H2AZ histone chaperone activity	40/3388	151/18639	0.264900662251656	1.4573445819683	0.00707531626413168	0.0632847732514
GO:0140537	transcription regulator activator activity	6/3388	11/18639	0.545454545454545	3.00080498014382	0.00718005873472774	0.0633418880159543
GO:1990948	ubiquitin ligase inhibitor activity	6/3388	11/18639	0.545454545454545	3.00080498014382	0.00718005873472774	0.0633418880159543
GO:0140223	general transcription initiation factor activity	21/3388	68/18639	0.308823529411765	1.69898517258143	0.00766308409451217	0.0671432130185828
GO:0015616	DNA translocase activity	40/3388	152/18639	0.263157894736842	1.44775678866588	0.0079544224895296	0.0692249740980684
GO:0004842	ubiquitin-protein transferase activity	102/3388	449/18639	0.2271714922049	1.24977846611781	0.00804674560478655	0.0695584452279535
GO:0017025	TBP-class protein binding	10/3388	25/18639	0.4	2.20059031877214	0.00886359302165502	0.0756046874959713
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	10/3388	25/18639	0.4	2.20059031877214	0.00886359302165502	0.0756046874959713
GO:0061775	cohesin loader activity	40/3388	153/18639	0.261437908496732	1.43829432599486	0.00892278339477094	0.0756088487662169
GO:0008409	5'-3' exonuclease activity	8/3388	18/18639	0.444444444444444	2.44510035419126	0.00912336246515766	0.0761970776174999
GO:1990381	ubiquitin-specific protease binding	8/3388	18/18639	0.444444444444444	2.44510035419126	0.00912336246515766	0.0761970776174999
GO:0008080	N-acetyltransferase activity	21/3388	69/18639	0.304347826086957	1.67436219906576	0.00916967937167119	0.0761970776174999
GO:0016755	aminoacyltransferase activity	111/3388	496/18639	0.223790322580645	1.23117704326465	0.00938867938339436	0.0775167887552047
GO:0004601	peroxidase activity	18/3388	57/18639	0.315789473684211	1.73730814639906	0.0101740514204397	0.0834661033727796
GO:0048029	monosaccharide binding	22/3388	74/18639	0.297297297297297	1.63557388557389	0.0104191694635667	0.0845366281643278
GO:0034212	protein N-acetyltransferase activity	17/3388	53/18639	0.320754716981132	1.76462431222294	0.0104358104643852	0.0845366281643278
GO:0000774	adenyl-nucleotide exchange factor activity	7/3388	15/18639	0.466666666666667	2.56735537190083	0.0107023369225342	0.0860113135789642
GO:0051539	4 iron, 4 sulfur cluster binding	15/3388	45/18639	0.333333333333333	1.83382526564345	0.0107514141973705	0.0860113135789642
GO:0008649	rRNA methyltransferase activity	9/3388	22/18639	0.409090909090909	2.25060373510787	0.0108796161176225	0.086499663947517
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	35/3388	132/18639	0.265151515151515	1.45872464312547	0.0110354769135193	0.087200578310508
GO:0016835	carbon-oxygen lyase activity	23/3388	79/18639	0.291139240506329	1.60169548518225	0.0116583841499443	0.0915609682020013
GO:0008198	ferrous iron binding	10/3388	26/18639	0.384615384615385	2.11595222958859	0.0120985338352837	0.0927611112905586
GO:0004032	aldose reductase (NADPH) activity	6/3388	12/18639	0.5	2.75073789846517	0.0121712948820686	0.0927611112905586
GO:0016423	tRNA (guanine) methyltransferase activity	6/3388	12/18639	0.5	2.75073789846517	0.0121712948820686	0.0927611112905586
GO:0035251	UDP-glucosyltransferase activity	6/3388	12/18639	0.5	2.75073789846517	0.0121712948820686	0.0927611112905586
GO:0070008	serine-type exopeptidase activity	6/3388	12/18639	0.5	2.75073789846517	0.0121712948820686	0.0927611112905586
GO:0035925	mRNA 3'-UTR AU-rich region binding	11/3388	30/18639	0.366666666666667	2.01720779220779	0.0128823540641789	0.097602776674485
GO:0051213	dioxygenase activity	26/3388	93/18639	0.279569892473118	1.53804699699128	0.0132575393120976	0.0992591668868908
GO:0120227	acyl-CoA binding	8/3388	19/18639	0.421052631578947	2.31641086186541	0.0132861207867223	0.0992591668868908
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	15/3388	46/18639	0.326086956521739	1.79395949899902	0.0133321707076336	0.0992591668868908
GO:0008238	exopeptidase activity	28/3388	102/18639	0.274509803921569	1.5102090422946	0.0134529394329953	0.0995826781017124
GO:1901981	phosphatidylinositol phosphate binding	46/3388	185/18639	0.248648648648649	1.36793452247998	0.0137533680976916	0.10122478919901
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	18/3388	59/18639	0.305084745762712	1.67841634482621	0.0147678840892452	0.108074060834931
GO:0008171	O-methyltransferase activity	9/3388	23/18639	0.391304347826087	2.15275139879883	0.0150432400970262	0.108852209241403
GO:0140102	catalytic activity, acting on a rRNA	9/3388	23/18639	0.391304347826087	2.15275139879883	0.0150432400970262	0.108852209241403
GO:0030544	Hsp70 protein binding	16/3388	51/18639	0.313725490196078	1.72595319119383	0.0158964643240413	0.113037244881551
GO:0000062	fatty-acyl-CoA binding	7/3388	16/18639	0.4375	2.40689566115702	0.0160851449107658	0.113037244881551
GO:0005521	lamin binding	7/3388	16/18639	0.4375	2.40689566115702	0.0160851449107658	0.113037244881551
GO:0017070	U6 snRNA binding	7/3388	16/18639	0.4375	2.40689566115702	0.0160851449107658	0.113037244881551
GO:0034450	ubiquitin-ubiquitin ligase activity	7/3388	16/18639	0.4375	2.40689566115702	0.0160851449107658	0.113037244881551
GO:0015252	proton channel activity	10/3388	27/18639	0.37037037037037	2.03758362849272	0.0161481778402216	0.113037244881551
GO:0008194	UDP-glycosyltransferase activity	37/3388	145/18639	0.255172413793103	1.40382485852705	0.0169595086443488	0.118074849372547
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	18/3388	60/18639	0.3	1.6504427390791	0.017602731964113	0.121894186934288
GO:0004521	RNA endonuclease activity	21/3388	73/18639	0.287671232876712	1.58261632514435	0.0177378652199014	0.122173103760605
GO:0043130	ubiquitin binding	27/3388	100/18639	0.27	1.48539846517119	0.0186388835080103	0.127305618474867
GO:0042288	MHC class I protein binding	8/3388	20/18639	0.4	2.20059031877214	0.0186807157544642	0.127305618474867
GO:0003689	DNA clamp loader activity	40/3388	160/18639	0.25	1.37536894923259	0.0187874443354532	0.127359096337177
GO:0030955	potassium ion binding	6/3388	13/18639	0.461538461538462	2.53914267550631	0.0191741612342498	0.129300102982794
GO:0046966	nuclear thyroid hormone receptor binding	10/3388	28/18639	0.357142857142857	1.96481278461798	0.0211201537244274	0.140946932627266
GO:0051537	2 iron, 2 sulfur cluster binding	10/3388	28/18639	0.357142857142857	1.96481278461798	0.0211201537244274	0.140946932627266
GO:0055106	ubiquitin-protein transferase regulator activity	12/3388	36/18639	0.333333333333333	1.83382526564345	0.0213850496636719	0.14197909261242
GO:0019902	phosphatase binding	46/3388	190/18639	0.242105263157895	1.33193624557261	0.0218212692111787	0.143499183168403
GO:0005528	FK506 binding	5/3388	10/18639	0.5	2.75073789846517	0.0221710694491555	0.143499183168403
GO:0016427	tRNA (cytidine) methyltransferase activity	5/3388	10/18639	0.5	2.75073789846517	0.0221710694491555	0.143499183168403
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	5/3388	10/18639	0.5	2.75073789846517	0.0221710694491555	0.143499183168403
GO:0030957	Tat protein binding	5/3388	10/18639	0.5	2.75073789846517	0.0221710694491555	0.143499183168403
GO:0008186	ATP-dependent activity, acting on RNA	22/3388	79/18639	0.278481012658228	1.53205655104389	0.0224531045519935	0.144597993314838
GO:0016829	lyase activity	48/3388	200/18639	0.24	1.32035419126328	0.0226623399771133	0.145219372589661
GO:1901567	fatty acid derivative binding	7/3388	17/18639	0.411764705882353	2.26531356344191	0.0231340422404445	0.14750815052323
GO:0008094	ATP-dependent activity, acting on DNA	50/3388	210/18639	0.238095238095238	1.30987518974532	0.0234258222176185	0.148632803035924
GO:0031267	small GTPase binding	65/3388	283/18639	0.229681978798587	1.26358984735149	0.0235995092788928	0.149000823290264
GO:0044183	protein folding chaperone	21/3388	75/18639	0.28	1.5404132231405	0.0238908943535903	0.150104741109387
GO:0010314	phosphatidylinositol-5-phosphate binding	8/3388	21/18639	0.380952380952381	2.09580030359251	0.02547346532074	0.159270987053947
GO:0004540	RNA nuclease activity	31/3388	121/18639	0.256198347107438	1.40946900582513	0.0256475629655107	0.159584836229844
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	78/3388	349/18639	0.223495702005731	1.22955619530248	0.0265854384155745	0.164625214804134
GO:0003925	G protein activity	16/3388	54/18639	0.296296296296296	1.63006690279418	0.0272884065838251	0.167322453155685
GO:0051287	NAD binding	16/3388	54/18639	0.296296296296296	1.63006690279418	0.0272884065838251	0.167322453155685
GO:0016410	N-acyltransferase activity	25/3388	94/18639	0.265957446808511	1.46315845663041	0.0274107434905663	0.167322453155685
GO:0030971	receptor tyrosine kinase binding	22/3388	81/18639	0.271604938271605	1.49422799422799	0.0295257970310941	0.179383144226647
GO:0070063	RNA polymerase binding	17/3388	59/18639	0.288135593220339	1.58517099233586	0.0303927649895848	0.183783480312607
GO:0008276	protein methyltransferase activity	25/3388	95/18639	0.263157894736842	1.44775678866588	0.0309701105026522	0.185406742869105
GO:0019207	kinase regulator activity	65/3388	287/18639	0.226480836236934	1.24597883902604	0.0310592582045804	0.185406742869105
GO:0030145	manganese ion binding	19/3388	68/18639	0.279411764705882	1.53717706090701	0.0312714597530514	0.185406742869105
GO:0004402	histone acetyltransferase activity	13/3388	42/18639	0.30952380952381	1.70283774666892	0.0313809549266032	0.185406742869105
GO:0031492	nucleosomal DNA binding	13/3388	42/18639	0.30952380952381	1.70283774666892	0.0313809549266032	0.185406742869105
GO:0003724	RNA helicase activity	21/3388	77/18639	0.272727272727273	1.50040249007191	0.0315570175749014	0.185595610212206
GO:0043531	ADP binding	12/3388	38/18639	0.315789473684211	1.73730814639906	0.0325744381049016	0.190708528541424
GO:0008376	acetylgalactosaminyltransferase activity	11/3388	34/18639	0.323529411764706	1.77988922841864	0.0335655771666211	0.19474082608382
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	11/3388	34/18639	0.323529411764706	1.77988922841864	0.0335655771666211	0.19474082608382
GO:0008106	alcohol dehydrogenase (NADP+) activity	10/3388	30/18639	0.333333333333333	1.83382526564345	0.0342348669050388	0.196850484703973
GO:0016769	transferase activity, transferring nitrogenous groups	10/3388	30/18639	0.333333333333333	1.83382526564345	0.0342348669050388	0.196850484703973
GO:0050750	low-density lipoprotein particle receptor binding	9/3388	26/18639	0.346153846153846	1.90435700662973	0.0344057323744696	0.196953703548075
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	5/3388	11/18639	0.454545454545455	2.50067081678652	0.0346635783778452	0.19755172102064
GO:0061733	protein-lysine-acetyltransferase activity	14/3388	47/18639	0.297872340425532	1.63873747142606	0.0358784477636663	0.203574628720715
GO:0001221	transcription coregulator binding	29/3388	115/18639	0.252173913043478	1.38732867922591	0.0365812172469011	0.206651788657932
GO:0019887	protein kinase regulator activity	58/3388	255/18639	0.227450980392157	1.25131606361553	0.0368666121776465	0.207354569802658
GO:0000149	SNARE binding	27/3388	106/18639	0.254716981132075	1.40131930676528	0.0379095656532771	0.212293567658352
GO:0003684	damaged DNA binding	20/3388	74/18639	0.27027027027027	1.48688535052171	0.0385697549442669	0.215055603325609
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	12/3388	39/18639	0.307692307692308	1.69276178367087	0.0395100095906019	0.219348673934031
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	6/3388	15/18639	0.4	2.20059031877214	0.0403443877719803	0.223019619958415
GO:0019905	syntaxin binding	17/3388	61/18639	0.278688524590164	1.53319817291501	0.0410934647252096	0.225582067786701
GO:0010485	histone H4 acetyltransferase activity	11/3388	35/18639	0.314285714285714	1.72903525046382	0.0411582188896544	0.225582067786701
GO:0016887	ATP hydrolysis activity	90/3388	417/18639	0.215827338129496	1.18736887703533	0.041377185981087	0.22582125230356
GO:0033218	amide binding	56/3388	247/18639	0.226720647773279	1.24729815638907	0.041881345660623	0.227608325784314
GO:0032266	phosphatidylinositol-3-phosphate binding	14/3388	48/18639	0.291666666666667	1.60459710743802	0.0424538997756212	0.229750516432773
GO:0031420	alkali metal ion binding	7/3388	19/18639	0.368421052631579	2.02685950413223	0.0429954843771849	0.231707882333951
GO:0008320	protein transmembrane transporter activity	9/3388	27/18639	0.333333333333333	1.83382526564345	0.0435345096415936	0.233635201743219
GO:0042626	ATPase-coupled transmembrane transporter activity	25/3388	98/18639	0.255102040816327	1.40343770329856	0.0437537395882476	0.233837413235116
GO:0001046	core promoter sequence-specific DNA binding	13/3388	44/18639	0.295454545454545	1.62543603091124	0.0449279316865194	0.238136526799329
GO:0016790	thiolester hydrolase activity	13/3388	44/18639	0.295454545454545	1.62543603091124	0.0449279316865194	0.238136526799329
GO:0016251	RNA polymerase II general transcription initiation factor activity	15/3388	53/18639	0.283018867924528	1.55702145196142	0.0467709634198326	0.246889347888297
GO:0004532	RNA exonuclease activity	12/3388	40/18639	0.3	1.6504427390791	0.0474168806958896	0.248263993237015
GO:0050997	quaternary ammonium group binding	12/3388	40/18639	0.3	1.6504427390791	0.0474168806958896	0.248263993237015
GO:0035091	phosphatidylinositol binding	63/3388	284/18639	0.221830985915493	1.22039780002328	0.0484219516471592	0.252499893609478
GO:0016922	nuclear receptor binding	33/3388	137/18639	0.240875912408759	1.3251730021803	0.0491919924796844	0.254239648897973
GO:0098631	cell adhesion mediator activity	20/3388	76/18639	0.263157894736842	1.44775678866588	0.0497593377786216	0.254239648897973
GO:0140034	methylation-dependent protein binding	20/3388	76/18639	0.263157894736842	1.44775678866588	0.0497593377786216	0.254239648897973
GO:0001222	transcription corepressor binding	14/3388	49/18639	0.285714285714286	1.57185022769438	0.0498350678627354	0.254239648897973
GO:0004033	aldo-keto reductase (NADPH) activity	11/3388	36/18639	0.305555555555556	1.68100649350649	0.0498584133490866	0.254239648897973
GO:0008408	3'-5' exonuclease activity	16/3388	58/18639	0.275862068965517	1.51764849570492	0.0506988742815882	0.254239648897973
GO:0000995	RNA polymerase III general transcription initiation factor activity	5/3388	12/18639	0.416666666666667	2.29228158205431	0.0507294951605428	0.254239648897973
GO:0005165	neurotrophin receptor binding	5/3388	12/18639	0.416666666666667	2.29228158205431	0.0507294951605428	0.254239648897973
GO:0005527	macrolide binding	5/3388	12/18639	0.416666666666667	2.29228158205431	0.0507294951605428	0.254239648897973
GO:0097371	MDM2/MDM4 family protein binding	5/3388	12/18639	0.416666666666667	2.29228158205431	0.0507294951605428	0.254239648897973
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	31/3388	128/18639	0.2421875	1.33238866956907	0.0518043014037197	0.258367180356635
GO:0022884	macromolecule transmembrane transporter activity	10/3388	32/18639	0.3125	1.71921118654073	0.0521548655999419	0.258367180356635
GO:0031369	translation initiation factor binding	10/3388	32/18639	0.3125	1.71921118654073	0.0521548655999419	0.258367180356635
GO:0005518	collagen binding	19/3388	72/18639	0.263888888888889	1.45177833530106	0.0534800307063544	0.263916779884232
GO:0046875	ephrin receptor binding	9/3388	28/18639	0.321428571428571	1.76833150615618	0.0541518361286726	0.265199866668176
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	9/3388	28/18639	0.321428571428571	1.76833150615618	0.0541518361286726	0.265199866668176
GO:0048027	mRNA 5'-UTR binding	8/3388	24/18639	0.333333333333333	1.83382526564345	0.0556005358032525	0.27126322013102
GO:0061608	nuclear import signal receptor activity	7/3388	20/18639	0.35	1.92551652892562	0.0560880520971113	0.272609098494639
GO:0140318	protein transporter activity	12/3388	41/18639	0.292682926829268	1.61018803812595	0.0563433004578562	0.272820191690672
GO:0140313	molecular sequestering activity	15/3388	55/18639	0.272727272727273	1.50040249007191	0.0625442504480981	0.301711590176593
GO:0003697	single-stranded DNA binding	29/3388	121/18639	0.239669421487603	1.31853552157835	0.0655145476896968	0.314860960538543
GO:0004386	helicase activity	36/3388	155/18639	0.232258064516129	1.27776212057737	0.0659217416308577	0.31564016067117
GO:0043175	RNA polymerase core enzyme binding	12/3388	42/18639	0.285714285714286	1.57185022769438	0.0663282386703574	0.316284744976173
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	16/3388	60/18639	0.266666666666667	1.46706021251476	0.0665474890438998	0.316284744976173
GO:0008483	transaminase activity	8/3388	25/18639	0.32	1.76047225501771	0.0692083127444475	0.327587124828321
GO:1990782	protein tyrosine kinase binding	28/3388	117/18639	0.239316239316239	1.31659249841068	0.0704452008902994	0.327587124828321
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	5/3388	13/18639	0.384615384615385	2.11595222958859	0.0704515788644759	0.327587124828321
GO:0005172	vascular endothelial growth factor receptor binding	5/3388	13/18639	0.384615384615385	2.11595222958859	0.0704515788644759	0.327587124828321
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	5/3388	13/18639	0.384615384615385	2.11595222958859	0.0704515788644759	0.327587124828321
GO:0140852	histone ubiquitin ligase activity	5/3388	13/18639	0.384615384615385	2.11595222958859	0.0704515788644759	0.327587124828321
GO:0004029	aldehyde dehydrogenase (NAD+) activity	6/3388	17/18639	0.352941176470588	1.94169734009306	0.0722267832604898	0.333434038851293
GO:0070402	NADPH binding	6/3388	17/18639	0.352941176470588	1.94169734009306	0.0722267832604898	0.333434038851293
GO:0004519	endonuclease activity	30/3388	127/18639	0.236220472440945	1.29956121187331	0.0725939946618585	0.333932375444549
GO:0004860	protein kinase inhibitor activity	21/3388	84/18639	0.25	1.37536894923259	0.0729470827385289	0.334362429064858
GO:0016831	carboxy-lyase activity	10/3388	34/18639	0.294117647058824	1.61808111674422	0.0753835461592299	0.344304990968398
GO:0003725	double-stranded RNA binding	19/3388	75/18639	0.253333333333333	1.39370720188902	0.0761524319297561	0.346587746733307
GO:0008200	ion channel inhibitor activity	12/3388	43/18639	0.27906976744186	1.53529557123637	0.0774004221310339	0.351027266566098
GO:0000049	tRNA binding	20/3388	80/18639	0.25	1.37536894923259	0.0786917637473192	0.355631549847534
GO:0043995	histone H4K5 acetyltransferase activity	9/3388	30/18639	0.3	1.6504427390791	0.080066984477036	0.356838325281738
GO:0043996	histone H4K8 acetyltransferase activity	9/3388	30/18639	0.3	1.6504427390791	0.080066984477036	0.356838325281738
GO:0043997	histone H4K12 acetyltransferase activity	9/3388	30/18639	0.3	1.6504427390791	0.080066984477036	0.356838325281738
GO:0051721	protein phosphatase 2A binding	9/3388	30/18639	0.3	1.6504427390791	0.080066984477036	0.356838325281738
GO:0016504	peptidase activator activity	15/3388	57/18639	0.263157894736842	1.44775678866588	0.0815571354635682	0.362226174058882
GO:0097602	cullin family protein binding	8/3388	26/18639	0.307692307692308	1.69276178367087	0.0846761262422152	0.373502913013607
GO:0120014	phospholipid transfer activity	8/3388	26/18639	0.307692307692308	1.69276178367087	0.0846761262422152	0.373502913013607
GO:0004864	protein phosphatase inhibitor activity	14/3388	53/18639	0.264150943396226	1.45322002183066	0.0880484702998241	0.384046238837416
GO:0051018	protein kinase A binding	14/3388	53/18639	0.264150943396226	1.45322002183066	0.0880484702998241	0.384046238837416
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	7/3388	22/18639	0.318181818181818	1.75046957175056	0.0889338631079257	0.384046238837416
GO:0140035	ubiquitin-like protein reader activity	7/3388	22/18639	0.318181818181818	1.75046957175056	0.0889338631079257	0.384046238837416
GO:0016229	steroid dehydrogenase activity	10/3388	35/18639	0.285714285714286	1.57185022769438	0.0890736770670603	0.384046238837416
GO:0016248	channel inhibitor activity	12/3388	44/18639	0.272727272727273	1.50040249007191	0.089577606047727	0.384046238837416
GO:0000182	rDNA binding	4/3388	10/18639	0.4	2.20059031877214	0.0909426264327732	0.384046238837416
GO:0003680	minor groove of adenine-thymine-rich DNA binding	4/3388	10/18639	0.4	2.20059031877214	0.0909426264327732	0.384046238837416
GO:0004090	carbonyl reductase (NADPH) activity	4/3388	10/18639	0.4	2.20059031877214	0.0909426264327732	0.384046238837416
GO:0016783	sulfurtransferase activity	4/3388	10/18639	0.4	2.20059031877214	0.0909426264327732	0.384046238837416
GO:0032052	bile acid binding	4/3388	10/18639	0.4	2.20059031877214	0.0909426264327732	0.384046238837416
GO:0070513	death domain binding	4/3388	10/18639	0.4	2.20059031877214	0.0909426264327732	0.384046238837416
GO:0098505	G-rich strand telomeric DNA binding	4/3388	10/18639	0.4	2.20059031877214	0.0909426264327732	0.384046238837416
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	6/3388	18/18639	0.333333333333333	1.83382526564345	0.0923152102056485	0.386045424496348
GO:0070064	proline-rich region binding	6/3388	18/18639	0.333333333333333	1.83382526564345	0.0923152102056485	0.386045424496348
GO:0070628	proteasome binding	6/3388	18/18639	0.333333333333333	1.83382526564345	0.0923152102056485	0.386045424496348
GO:0070273	phosphatidylinositol-4-phosphate binding	9/3388	31/18639	0.290322580645161	1.59720265072171	0.0954119748179602	0.396421366340428
GO:0070325	lipoprotein particle receptor binding	9/3388	31/18639	0.290322580645161	1.59720265072171	0.0954119748179602	0.396421366340428
GO:0061791	GTPase motor activity	11/3388	40/18639	0.275	1.51290584415584	0.0965795935039494	0.39742657007376
GO:0071949	FAD binding	11/3388	40/18639	0.275	1.51290584415584	0.0965795935039494	0.39742657007376
GO:1990606	membrane scission GTPase motor activity	11/3388	40/18639	0.275	1.51290584415584	0.0965795935039494	0.39742657007376
GO:1902936	phosphatidylinositol bisphosphate binding	26/3388	111/18639	0.234234234234234	1.28863397045215	0.0970437105659693	0.39806464716232
GO:0005385	zinc ion transmembrane transporter activity	8/3388	27/18639	0.296296296296296	1.63006690279418	0.101998912179319	0.415902736832266
GO:0043539	protein serine/threonine kinase activator activity	18/3388	73/18639	0.246575342465753	1.35652827869515	0.102038249098599	0.415902736832266
GO:0141110	transporter inhibitor activity	12/3388	45/18639	0.266666666666667	1.46706021251476	0.102866093062383	0.417954346575235
GO:0000993	RNA polymerase II complex binding	10/3388	36/18639	0.277777777777778	1.52818772136954	0.104156470804743	0.421866460366379
GO:0001540	amyloid-beta binding	20/3388	83/18639	0.240963855421687	1.32565681853743	0.10657194156222	0.430296742107018
GO:0004602	glutathione peroxidase activity	7/3388	23/18639	0.304347826086957	1.67436219906576	0.108669759059758	0.437395780215525
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	9/3388	32/18639	0.28125	1.54729006788666	0.112338669729358	0.446882674275124
GO:0051059	NF-kappaB binding	9/3388	32/18639	0.28125	1.54729006788666	0.112338669729358	0.446882674275124
GO:0008374	O-acyltransferase activity	14/3388	55/18639	0.254545454545455	1.40037565740045	0.112619329613644	0.446882674275124
GO:0035064	methylated histone binding	18/3388	74/18639	0.243243243243243	1.33819681546954	0.112984347247705	0.446882674275124
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	6/3388	19/18639	0.315789473684211	1.73730814639906	0.115078160588016	0.446882674275124
GO:0008301	DNA binding, bending	6/3388	19/18639	0.315789473684211	1.73730814639906	0.115078160588016	0.446882674275124
GO:0050145	nucleoside monophosphate kinase activity	6/3388	19/18639	0.315789473684211	1.73730814639906	0.115078160588016	0.446882674275124
GO:0070003	threonine-type peptidase activity	6/3388	19/18639	0.315789473684211	1.73730814639906	0.115078160588016	0.446882674275124
GO:0097001	ceramide binding	6/3388	19/18639	0.315789473684211	1.73730814639906	0.115078160588016	0.446882674275124
GO:0140036	ubiquitin-modified protein reader activity	6/3388	19/18639	0.315789473684211	1.73730814639906	0.115078160588016	0.446882674275124
GO:0033293	monocarboxylic acid binding	19/3388	79/18639	0.240506329113924	1.32313974862882	0.115190254549178	0.446882674275124
GO:0046332	SMAD binding	19/3388	79/18639	0.240506329113924	1.32313974862882	0.115190254549178	0.446882674275124
GO:0003727	single-stranded RNA binding	21/3388	89/18639	0.235955056179775	1.29810103073637	0.118693193424172	0.459089588979981
GO:0034483	heparan sulfate sulfotransferase activity	5/3388	15/18639	0.333333333333333	1.83382526564345	0.120475183937619	0.459581107866199
GO:0050780	dopamine receptor binding	5/3388	15/18639	0.333333333333333	1.83382526564345	0.120475183937619	0.459581107866199
GO:0120283	protein serine/threonine kinase binding	5/3388	15/18639	0.333333333333333	1.83382526564345	0.120475183937619	0.459581107866199
GO:0019789	SUMO transferase activity	8/3388	28/18639	0.285714285714286	1.57185022769438	0.121137742599578	0.459581107866199
GO:0036408	histone H3K14 acetyltransferase activity	8/3388	28/18639	0.285714285714286	1.57185022769438	0.121137742599578	0.459581107866199
GO:0050698	proteoglycan sulfotransferase activity	8/3388	28/18639	0.285714285714286	1.57185022769438	0.121137742599578	0.459581107866199
GO:0016830	carbon-carbon lyase activity	13/3388	51/18639	0.254901960784314	1.40233696784499	0.122181247456462	0.459581107866199
GO:0005536	D-glucose binding	4/3388	11/18639	0.363636363636364	2.00053665342922	0.12310208246416	0.459581107866199
GO:0008526	phosphatidylinositol transfer activity	4/3388	11/18639	0.363636363636364	2.00053665342922	0.12310208246416	0.459581107866199
GO:0032404	mismatch repair complex binding	4/3388	11/18639	0.363636363636364	2.00053665342922	0.12310208246416	0.459581107866199
GO:0034511	U3 snoRNA binding	4/3388	11/18639	0.363636363636364	2.00053665342922	0.12310208246416	0.459581107866199
GO:0048407	platelet-derived growth factor binding	4/3388	11/18639	0.363636363636364	2.00053665342922	0.12310208246416	0.459581107866199
GO:0035591	signaling adaptor activity	29/3388	129/18639	0.224806201550388	1.2367658768293	0.124889470580021	0.464906468517536
GO:0019212	phosphatase inhibitor activity	14/3388	56/18639	0.25	1.37536894923259	0.126280578611132	0.468730216862071
GO:0035198	miRNA binding	11/3388	42/18639	0.261904761904762	1.44086270871985	0.127302297248444	0.47116482429884
GO:0019210	kinase inhibitor activity	21/3388	90/18639	0.233333333333333	1.28367768595041	0.12956271467282	0.47730503918104
GO:0016836	hydro-lyase activity	15/3388	61/18639	0.245901639344262	1.35282191727795	0.129702456299196	0.47730503918104
GO:0070300	phosphatidic acid binding	7/3388	24/18639	0.291666666666667	1.60459710743802	0.130521792165378	0.478642451060413
GO:0140311	protein sequestering activity	9/3388	33/18639	0.272727272727273	1.50040249007191	0.130809117059989	0.478642451060413
GO:0005504	fatty acid binding	12/3388	47/18639	0.25531914893617	1.40463211836519	0.132743793528372	0.482977418261421
GO:1990518	single-stranded 3'-5' DNA helicase activity	12/3388	47/18639	0.25531914893617	1.40463211836519	0.132743793528372	0.482977418261421
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	10/3388	38/18639	0.263157894736842	1.44775678866588	0.138414639456832	0.502191705972958
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	6/3388	20/18639	0.3	1.6504427390791	0.140359635655547	0.504981035542861
GO:0015095	magnesium ion transmembrane transporter activity	6/3388	20/18639	0.3	1.6504427390791	0.140359635655547	0.504981035542861
GO:0016004	phospholipase activator activity	6/3388	20/18639	0.3	1.6504427390791	0.140359635655547	0.504981035542861
GO:0010484	histone H3 acetyltransferase activity	8/3388	29/18639	0.275862068965517	1.51764849570492	0.142021701987822	0.508122089334206
GO:0016417	S-acyltransferase activity	8/3388	29/18639	0.275862068965517	1.51764849570492	0.142021701987822	0.508122089334206
GO:0044325	transmembrane transporter binding	30/3388	136/18639	0.220588235294118	1.21356083755816	0.143554132945237	0.511152236440192
GO:0004712	protein serine/threonine/tyrosine kinase activity	11/3388	43/18639	0.255813953488372	1.40735427363334	0.144456066820054	0.511152236440192
GO:0008375	acetylglucosaminyltransferase activity	11/3388	43/18639	0.255813953488372	1.40735427363334	0.144456066820054	0.511152236440192
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	11/3388	43/18639	0.255813953488372	1.40735427363334	0.144456066820054	0.511152236440192
GO:0031406	carboxylic acid binding	40/3388	187/18639	0.213903743315508	1.17678626672307	0.147172042529819	0.51933586514632
GO:0043138	3'-5' DNA helicase activity	12/3388	48/18639	0.25	1.37536894923259	0.149287506664964	0.523453219855536
GO:0016874	ligase activity	36/3388	167/18639	0.215568862275449	1.18594687838019	0.150070958244662	0.523453219855536
GO:0005149	interleukin-1 receptor binding	5/3388	16/18639	0.3125	1.71921118654073	0.150282115959851	0.523453219855536
GO:0008142	oxysterol binding	5/3388	16/18639	0.3125	1.71921118654073	0.150282115959851	0.523453219855536
GO:0022804	active transmembrane transporter activity	92/3388	457/18639	0.201312910284464	1.10751810353959	0.150370878374649	0.523453219855536
GO:0052689	carboxylic ester hydrolase activity	21/3388	92/18639	0.228260869565217	1.25577164929932	0.153000193003875	0.531170481371944
GO:0019706	protein-cysteine S-palmitoyltransferase activity	7/3388	25/18639	0.28	1.5404132231405	0.154365923051295	0.53303836163557
GO:0019707	protein-cysteine S-acyltransferase activity	7/3388	25/18639	0.28	1.5404132231405	0.154365923051295	0.53303836163557
GO:0061980	regulatory RNA binding	14/3388	58/18639	0.241379310344828	1.32794243374181	0.156279898781556	0.538204571204929
GO:0000340	RNA 7-methylguanosine cap binding	4/3388	12/18639	0.333333333333333	1.83382526564345	0.159288376115969	0.538486688811991
GO:0008603	cAMP-dependent protein kinase regulator activity	4/3388	12/18639	0.333333333333333	1.83382526564345	0.159288376115969	0.538486688811991
GO:0010853	cyclase activator activity	4/3388	12/18639	0.333333333333333	1.83382526564345	0.159288376115969	0.538486688811991
GO:0016801	hydrolase activity, acting on ether bonds	4/3388	12/18639	0.333333333333333	1.83382526564345	0.159288376115969	0.538486688811991
GO:0016803	ether hydrolase activity	4/3388	12/18639	0.333333333333333	1.83382526564345	0.159288376115969	0.538486688811991
GO:0043047	single-stranded telomeric DNA binding	4/3388	12/18639	0.333333333333333	1.83382526564345	0.159288376115969	0.538486688811991
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	4/3388	12/18639	0.333333333333333	1.83382526564345	0.159288376115969	0.538486688811991
GO:0019209	kinase activator activity	32/3388	148/18639	0.216216216216216	1.18950828041737	0.162220763216477	0.545886892072437
GO:0001223	transcription coactivator binding	11/3388	44/18639	0.25	1.37536894923259	0.162748887077497	0.545886892072437
GO:0019205	nucleobase-containing compound kinase activity	11/3388	44/18639	0.25	1.37536894923259	0.162748887077497	0.545886892072437
GO:0043177	organic acid binding	40/3388	189/18639	0.211640211640212	1.16433350199584	0.164297948964357	0.549070696744942
GO:0031210	phosphatidylcholine binding	8/3388	30/18639	0.266666666666667	1.46706021251476	0.164550690173562	0.549070696744942
GO:0008170	N-methyltransferase activity	22/3388	98/18639	0.224489795918367	1.23502517890273	0.165805753017193	0.551828966114069
GO:0070182	DNA polymerase binding	6/3388	21/18639	0.285714285714286	1.57185022769438	0.167945351723647	0.554650289795018
GO:0140312	cargo adaptor activity	6/3388	21/18639	0.285714285714286	1.57185022769438	0.167945351723647	0.554650289795018
GO:1904047	S-adenosyl-L-methionine binding	6/3388	21/18639	0.285714285714286	1.57185022769438	0.167945351723647	0.554650289795018
GO:0140463	chromatin-protein adaptor activity	13/3388	54/18639	0.240740740740741	1.32442935852027	0.170063032549733	0.560207636634414
GO:0000175	3'-5'-RNA exonuclease activity	9/3388	35/18639	0.257142857142857	1.41466520492495	0.172116084494062	0.564085284550515
GO:0043015	gamma-tubulin binding	9/3388	35/18639	0.257142857142857	1.41466520492495	0.172116084494062	0.564085284550515
GO:0004536	DNA nuclease activity	15/3388	64/18639	0.234375	1.28940838990555	0.174495379427011	0.570431595690329
GO:0030331	nuclear estrogen receptor binding	10/3388	40/18639	0.25	1.37536894923259	0.177810133843471	0.57979608200099
GO:0004529	DNA exonuclease activity	7/3388	26/18639	0.269230769230769	1.48116656071202	0.180041111349377	0.579933646728106
GO:0046915	transition metal ion transmembrane transporter activity	11/3388	45/18639	0.244444444444444	1.34480519480519	0.182122732200034	0.579933646728106
GO:0019842	vitamin binding	32/3388	150/18639	0.213333333333333	1.17364817001181	0.182792198632252	0.579933646728106
GO:0008484	sulfuric ester hydrolase activity	5/3388	17/18639	0.294117647058824	1.61808111674422	0.182805171251251	0.579933646728106
GO:0016018	cyclosporin A binding	5/3388	17/18639	0.294117647058824	1.61808111674422	0.182805171251251	0.579933646728106
GO:0017110	nucleoside diphosphate phosphatase activity	5/3388	17/18639	0.294117647058824	1.61808111674422	0.182805171251251	0.579933646728106
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	5/3388	17/18639	0.294117647058824	1.61808111674422	0.182805171251251	0.579933646728106
GO:0031489	myosin V binding	5/3388	17/18639	0.294117647058824	1.61808111674422	0.182805171251251	0.579933646728106
GO:0036041	long-chain fatty acid binding	5/3388	17/18639	0.294117647058824	1.61808111674422	0.182805171251251	0.579933646728106
GO:0051787	misfolded protein binding	5/3388	17/18639	0.294117647058824	1.61808111674422	0.182805171251251	0.579933646728106
GO:1990226	histone methyltransferase binding	5/3388	17/18639	0.294117647058824	1.61808111674422	0.182805171251251	0.579933646728106
GO:0015605	organophosphate ester transmembrane transporter activity	12/3388	50/18639	0.24	1.32035419126328	0.185388339715148	0.586683492759484
GO:0008327	methyl-CpG binding	8/3388	31/18639	0.258064516129032	1.41973568953041	0.188598938992902	0.59538096427171
GO:0160215	deacylase activity	15/3388	65/18639	0.230769230769231	1.26957133775316	0.190963787080046	0.595389673223774
GO:0016782	transferase activity, transferring sulphur-containing groups	16/3388	70/18639	0.228571428571429	1.25748018215551	0.191854374964917	0.595389673223774
GO:0016881	acid-amino acid ligase activity	6/3388	22/18639	0.272727272727273	1.50040249007191	0.197574659954542	0.595389673223774
GO:0032931	histone H3K56 acetyltransferase activity	6/3388	22/18639	0.272727272727273	1.50040249007191	0.197574659954542	0.595389673223774
GO:0034062	5'-3' RNA polymerase activity	6/3388	22/18639	0.272727272727273	1.50040249007191	0.197574659954542	0.595389673223774
GO:0043992	histone H3K9 acetyltransferase activity	6/3388	22/18639	0.272727272727273	1.50040249007191	0.197574659954542	0.595389673223774
GO:0043993	histone H3K18 acetyltransferase activity	6/3388	22/18639	0.272727272727273	1.50040249007191	0.197574659954542	0.595389673223774
GO:0043994	histone H3K23 acetyltransferase activity	6/3388	22/18639	0.272727272727273	1.50040249007191	0.197574659954542	0.595389673223774
GO:0043999	histone H2AK5 acetyltransferase activity	6/3388	22/18639	0.272727272727273	1.50040249007191	0.197574659954542	0.595389673223774
GO:0044012	histone H2AK9 acetyltransferase activity	6/3388	22/18639	0.272727272727273	1.50040249007191	0.197574659954542	0.595389673223774
GO:0044014	histone H2BK5 acetyltransferase activity	6/3388	22/18639	0.272727272727273	1.50040249007191	0.197574659954542	0.595389673223774
GO:0044015	histone H2BK12 acetyltransferase activity	6/3388	22/18639	0.272727272727273	1.50040249007191	0.197574659954542	0.595389673223774
GO:0044016	histone H3K4 acetyltransferase activity	6/3388	22/18639	0.272727272727273	1.50040249007191	0.197574659954542	0.595389673223774
GO:0044017	histone H3K27 acetyltransferase activity	6/3388	22/18639	0.272727272727273	1.50040249007191	0.197574659954542	0.595389673223774
GO:0044018	histone H3K36 acetyltransferase activity	6/3388	22/18639	0.272727272727273	1.50040249007191	0.197574659954542	0.595389673223774
GO:0061133	endopeptidase activator activity	6/3388	22/18639	0.272727272727273	1.50040249007191	0.197574659954542	0.595389673223774
GO:0070034	telomerase RNA binding	6/3388	22/18639	0.272727272727273	1.50040249007191	0.197574659954542	0.595389673223774
GO:0097747	RNA polymerase activity	6/3388	22/18639	0.272727272727273	1.50040249007191	0.197574659954542	0.595389673223774
GO:0140908	histone H3K122 acetyltransferase activity	6/3388	22/18639	0.272727272727273	1.50040249007191	0.197574659954542	0.595389673223774
GO:0019855	calcium channel inhibitor activity	4/3388	13/18639	0.307692307692308	1.69276178367087	0.198771397116633	0.595389673223774
GO:0051011	microtubule minus-end binding	4/3388	13/18639	0.307692307692308	1.69276178367087	0.198771397116633	0.595389673223774
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	4/3388	13/18639	0.307692307692308	1.69276178367087	0.198771397116633	0.595389673223774
GO:0005048	signal sequence binding	12/3388	51/18639	0.235294117647059	1.29446489339537	0.204836675794743	0.612133731841367
GO:0004364	glutathione transferase activity	7/3388	27/18639	0.259259259259259	1.4263085399449	0.207355881058897	0.617709808110661
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	19/3388	86/18639	0.22093023255814	1.2154423272288	0.207690496738407	0.617709808110661
GO:0008235	metalloexopeptidase activity	15/3388	66/18639	0.227272727272727	1.25033540839326	0.208141348385114	0.617709808110661
GO:0019208	phosphatase regulator activity	25/3388	117/18639	0.213675213675214	1.17552901643811	0.215475382556228	0.637180909187503
GO:0008237	metallopeptidase activity	38/3388	184/18639	0.206521739130435	1.13617434936605	0.215691674228068	0.637180909187503
GO:0000900	mRNA regulatory element binding translation repressor activity	5/3388	18/18639	0.277777777777778	1.52818772136954	0.217609002422636	0.638451925103316
GO:0017075	syntaxin-1 binding	5/3388	18/18639	0.277777777777778	1.52818772136954	0.217609002422636	0.638451925103316
GO:0035615	clathrin adaptor activity	5/3388	18/18639	0.277777777777778	1.52818772136954	0.217609002422636	0.638451925103316
GO:0019888	protein phosphatase regulator activity	23/3388	107/18639	0.214953271028037	1.18256021803176	0.218309356880049	0.639051026503417
GO:0048487	beta-tubulin binding	10/3388	42/18639	0.238095238095238	1.30987518974532	0.221739435413995	0.647619938351984
GO:0004857	enzyme inhibitor activity	82/3388	416/18639	0.197115384615385	1.08442551766415	0.22299817271719	0.649822729546926
GO:0061749	forked DNA-dependent helicase activity	11/3388	47/18639	0.234042553191489	1.28757944183476	0.223824846129947	0.650759372043728
GO:0030159	signaling receptor complex adaptor activity	12/3388	52/18639	0.230769230769231	1.26957133775316	0.225129677342224	0.653078883821588
GO:0015932	nucleobase-containing compound transmembrane transporter activity	13/3388	57/18639	0.228070175438596	1.2547225501771	0.225840993420863	0.653670111294543
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	6/3388	23/18639	0.260869565217391	1.43516759919922	0.228952860270349	0.653860940195585
GO:0017134	fibroblast growth factor binding	6/3388	23/18639	0.260869565217391	1.43516759919922	0.228952860270349	0.653860940195585
GO:0031681	G-protein beta-subunit binding	6/3388	23/18639	0.260869565217391	1.43516759919922	0.228952860270349	0.653860940195585
GO:0042171	lysophosphatidic acid acyltransferase activity	6/3388	23/18639	0.260869565217391	1.43516759919922	0.228952860270349	0.653860940195585
GO:0044013	histone H2B acetyltransferase activity	6/3388	23/18639	0.260869565217391	1.43516759919922	0.228952860270349	0.653860940195585
GO:0071617	lysophospholipid acyltransferase activity	6/3388	23/18639	0.260869565217391	1.43516759919922	0.228952860270349	0.653860940195585
GO:0030295	protein kinase activator activity	29/3388	139/18639	0.20863309352518	1.14778991446748	0.234149392827275	0.667222163631703
GO:1901681	sulfur compound binding	55/3388	275/18639	0.2	1.10029515938607	0.236071748474287	0.668331199082183
GO:0046625	sphingolipid binding	7/3388	28/18639	0.25	1.37536894923259	0.236095260545337	0.668331199082183
GO:0097718	disordered domain specific binding	7/3388	28/18639	0.25	1.37536894923259	0.236095260545337	0.668331199082183
GO:0004197	cysteine-type endopeptidase activity	19/3388	88/18639	0.215909090909091	1.1878186379736	0.239184254994956	0.669798914134406
GO:0004065	arylsulfatase activity	4/3388	14/18639	0.285714285714286	1.57185022769438	0.240773988543657	0.669798914134406
GO:0008494	translation activator activity	4/3388	14/18639	0.285714285714286	1.57185022769438	0.240773988543657	0.669798914134406
GO:0034236	protein kinase A catalytic subunit binding	4/3388	14/18639	0.285714285714286	1.57185022769438	0.240773988543657	0.669798914134406
GO:0042043	neurexin family protein binding	4/3388	14/18639	0.285714285714286	1.57185022769438	0.240773988543657	0.669798914134406
GO:0044548	S100 protein binding	4/3388	14/18639	0.285714285714286	1.57185022769438	0.240773988543657	0.669798914134406
GO:0098847	sequence-specific single stranded DNA binding	4/3388	14/18639	0.285714285714286	1.57185022769438	0.240773988543657	0.669798914134406
GO:1990825	sequence-specific mRNA binding	4/3388	14/18639	0.285714285714286	1.57185022769438	0.240773988543657	0.669798914134406
GO:0017116	single-stranded DNA helicase activity	13/3388	58/18639	0.224137931034483	1.23308940276025	0.245936420761107	0.678432889212837
GO:0009378	four-way junction helicase activity	11/3388	48/18639	0.229166666666667	1.26075487012987	0.245984595700617	0.678432889212837
GO:0016879	ligase activity, forming carbon-nitrogen bonds	11/3388	48/18639	0.229166666666667	1.26075487012987	0.245984595700617	0.678432889212837
GO:0036121	double-stranded DNA helicase activity	11/3388	48/18639	0.229166666666667	1.26075487012987	0.245984595700617	0.678432889212837
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	5/3388	19/18639	0.263157894736842	1.44775678866588	0.254227160220715	0.692956650463682
GO:0005346	purine ribonucleotide transmembrane transporter activity	5/3388	19/18639	0.263157894736842	1.44775678866588	0.254227160220715	0.692956650463682
GO:0042800	histone H3K4 methyltransferase activity	5/3388	19/18639	0.263157894736842	1.44775678866588	0.254227160220715	0.692956650463682
GO:0043998	histone H2A acetyltransferase activity	6/3388	24/18639	0.25	1.37536894923259	0.261763216305339	0.692956650463682
GO:0060229	lipase activator activity	6/3388	24/18639	0.25	1.37536894923259	0.261763216305339	0.692956650463682
GO:0002039	p53 binding	15/3388	69/18639	0.217391304347826	1.19597299933268	0.263466901448422	0.692956650463682
GO:0106222	lncRNA binding	7/3388	29/18639	0.241379310344828	1.32794243374181	0.26602775645	0.692956650463682
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	3/3388	10/18639	0.3	1.6504427390791	0.267928891250709	0.692956650463682
GO:0004445	inositol-polyphosphate 5-phosphatase activity	3/3388	10/18639	0.3	1.6504427390791	0.267928891250709	0.692956650463682
GO:0004862	cAMP-dependent protein kinase inhibitor activity	3/3388	10/18639	0.3	1.6504427390791	0.267928891250709	0.692956650463682
GO:0005381	iron ion transmembrane transporter activity	3/3388	10/18639	0.3	1.6504427390791	0.267928891250709	0.692956650463682
GO:0005522	profilin binding	3/3388	10/18639	0.3	1.6504427390791	0.267928891250709	0.692956650463682
GO:0008190	eukaryotic initiation factor 4E binding	3/3388	10/18639	0.3	1.6504427390791	0.267928891250709	0.692956650463682
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	3/3388	10/18639	0.3	1.6504427390791	0.267928891250709	0.692956650463682
GO:0015203	polyamine transmembrane transporter activity	3/3388	10/18639	0.3	1.6504427390791	0.267928891250709	0.692956650463682
GO:0015279	store-operated calcium channel activity	3/3388	10/18639	0.3	1.6504427390791	0.267928891250709	0.692956650463682
GO:0015924	mannosyl-oligosaccharide mannosidase activity	3/3388	10/18639	0.3	1.6504427390791	0.267928891250709	0.692956650463682
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	3/3388	10/18639	0.3	1.6504427390791	0.267928891250709	0.692956650463682
GO:0032356	oxidized DNA binding	3/3388	10/18639	0.3	1.6504427390791	0.267928891250709	0.692956650463682
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	3/3388	10/18639	0.3	1.6504427390791	0.267928891250709	0.692956650463682
GO:0042975	peroxisome proliferator activated receptor binding	3/3388	10/18639	0.3	1.6504427390791	0.267928891250709	0.692956650463682
GO:0043208	glycosphingolipid binding	3/3388	10/18639	0.3	1.6504427390791	0.267928891250709	0.692956650463682
GO:0043422	protein kinase B binding	3/3388	10/18639	0.3	1.6504427390791	0.267928891250709	0.692956650463682
GO:0045322	unmethylated CpG binding	3/3388	10/18639	0.3	1.6504427390791	0.267928891250709	0.692956650463682
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	3/3388	10/18639	0.3	1.6504427390791	0.267928891250709	0.692956650463682
GO:0050815	phosphoserine residue binding	3/3388	10/18639	0.3	1.6504427390791	0.267928891250709	0.692956650463682
GO:0051880	G-quadruplex DNA binding	3/3388	10/18639	0.3	1.6504427390791	0.267928891250709	0.692956650463682
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	3/3388	10/18639	0.3	1.6504427390791	0.267928891250709	0.692956650463682
GO:0099122	RNA polymerase II C-terminal domain binding	3/3388	10/18639	0.3	1.6504427390791	0.267928891250709	0.692956650463682
GO:0140999	histone H3K4 trimethyltransferase activity	3/3388	10/18639	0.3	1.6504427390791	0.267928891250709	0.692956650463682
GO:0141109	transporter activator activity	3/3388	10/18639	0.3	1.6504427390791	0.267928891250709	0.692956650463682
GO:0016776	phosphotransferase activity, phosphate group as acceptor	9/3388	39/18639	0.230769230769231	1.26957133775316	0.269287646014814	0.695075126386934
GO:0048306	calcium-dependent protein binding	17/3388	80/18639	0.2125	1.1690636068477	0.277796559024051	0.715603936045956
GO:0097110	scaffold protein binding	15/3388	70/18639	0.214285714285714	1.17888767077079	0.282997590489377	0.724230203201012
GO:0004559	alpha-mannosidase activity	4/3388	15/18639	0.266666666666667	1.46706021251476	0.284519008400398	0.724230203201012
GO:0005041	low-density lipoprotein particle receptor activity	4/3388	15/18639	0.266666666666667	1.46706021251476	0.284519008400398	0.724230203201012
GO:0008242	omega peptidase activity	4/3388	15/18639	0.266666666666667	1.46706021251476	0.284519008400398	0.724230203201012
GO:0016846	carbon-sulfur lyase activity	4/3388	15/18639	0.266666666666667	1.46706021251476	0.284519008400398	0.724230203201012
GO:0050700	CARD domain binding	4/3388	15/18639	0.266666666666667	1.46706021251476	0.284519008400398	0.724230203201012
GO:0098632	cell-cell adhesion mediator activity	12/3388	55/18639	0.218181818181818	1.20032199205753	0.290297232599649	0.732610651892652
GO:0016505	peptidase activator activity involved in apoptotic process	5/3388	20/18639	0.25	1.37536894923259	0.292183001742438	0.732610651892652
GO:0030742	GTP-dependent protein binding	5/3388	20/18639	0.25	1.37536894923259	0.292183001742438	0.732610651892652
GO:0005506	iron ion binding	31/3388	154/18639	0.201298701298701	1.10743993314832	0.293988838136951	0.732610651892652
GO:0000030	mannosyltransferase activity	6/3388	25/18639	0.24	1.32035419126328	0.295678151017142	0.732610651892652
GO:0015662	P-type ion transporter activity	6/3388	25/18639	0.24	1.32035419126328	0.295678151017142	0.732610651892652
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	6/3388	25/18639	0.24	1.32035419126328	0.295678151017142	0.732610651892652
GO:0017056	structural constituent of nuclear pore	6/3388	25/18639	0.24	1.32035419126328	0.295678151017142	0.732610651892652
GO:0019211	phosphatase activator activity	6/3388	25/18639	0.24	1.32035419126328	0.295678151017142	0.732610651892652
GO:0047617	fatty acyl-CoA hydrolase activity	6/3388	25/18639	0.24	1.32035419126328	0.295678151017142	0.732610651892652
GO:0140358	P-type transmembrane transporter activity	6/3388	25/18639	0.24	1.32035419126328	0.295678151017142	0.732610651892652
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	9/3388	40/18639	0.225	1.23783205430933	0.295845633419397	0.732610651892652
GO:0140662	ATP-dependent protein folding chaperone	9/3388	40/18639	0.225	1.23783205430933	0.295845633419397	0.732610651892652
GO:0005154	epidermal growth factor receptor binding	8/3388	35/18639	0.228571428571429	1.25748018215551	0.296802539432534	0.732610651892652
GO:0140566	histone reader activity	8/3388	35/18639	0.228571428571429	1.25748018215551	0.296802539432534	0.732610651892652
GO:0001968	fibronectin binding	7/3388	30/18639	0.233333333333333	1.28367768595041	0.296912080968916	0.732610651892652
GO:0140767	enzyme-substrate adaptor activity	28/3388	139/18639	0.201438848920863	1.10821095189964	0.304872207160067	0.750813389717334
GO:0030291	protein serine/threonine kinase inhibitor activity	10/3388	46/18639	0.217391304347826	1.19597299933268	0.319838982460537	0.764045448703985
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	3/3388	11/18639	0.272727272727273	1.50040249007191	0.322238944545665	0.764045448703985
GO:0004016	adenylate cyclase activity	3/3388	11/18639	0.272727272727273	1.50040249007191	0.322238944545665	0.764045448703985
GO:0004143	ATP-dependent diacylglycerol kinase activity	3/3388	11/18639	0.272727272727273	1.50040249007191	0.322238944545665	0.764045448703985
GO:0008199	ferric iron binding	3/3388	11/18639	0.272727272727273	1.50040249007191	0.322238944545665	0.764045448703985
GO:0008432	JUN kinase binding	3/3388	11/18639	0.272727272727273	1.50040249007191	0.322238944545665	0.764045448703985
GO:0010854	adenylate cyclase regulator activity	3/3388	11/18639	0.272727272727273	1.50040249007191	0.322238944545665	0.764045448703985
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	3/3388	11/18639	0.272727272727273	1.50040249007191	0.322238944545665	0.764045448703985
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	3/3388	11/18639	0.272727272727273	1.50040249007191	0.322238944545665	0.764045448703985
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	3/3388	11/18639	0.272727272727273	1.50040249007191	0.322238944545665	0.764045448703985
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	3/3388	11/18639	0.272727272727273	1.50040249007191	0.322238944545665	0.764045448703985
GO:0019107	myristoyltransferase activity	3/3388	11/18639	0.272727272727273	1.50040249007191	0.322238944545665	0.764045448703985
GO:0019206	nucleoside kinase activity	3/3388	11/18639	0.272727272727273	1.50040249007191	0.322238944545665	0.764045448703985
GO:0032794	GTPase activating protein binding	3/3388	11/18639	0.272727272727273	1.50040249007191	0.322238944545665	0.764045448703985
GO:0035252	UDP-xylosyltransferase activity	3/3388	11/18639	0.272727272727273	1.50040249007191	0.322238944545665	0.764045448703985
GO:0042285	xylosyltransferase activity	3/3388	11/18639	0.272727272727273	1.50040249007191	0.322238944545665	0.764045448703985
GO:0070990	snRNP binding	3/3388	11/18639	0.272727272727273	1.50040249007191	0.322238944545665	0.764045448703985
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	3/3388	11/18639	0.272727272727273	1.50040249007191	0.322238944545665	0.764045448703985
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	9/3388	41/18639	0.219512195121951	1.20764102859447	0.323011917110574	0.764045448703985
GO:0042169	SH2 domain binding	9/3388	41/18639	0.219512195121951	1.20764102859447	0.323011917110574	0.764045448703985
GO:0016409	palmitoyltransferase activity	8/3388	36/18639	0.222222222222222	1.22255017709563	0.325954896682638	0.764045448703985
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	14/3388	67/18639	0.208955223880597	1.14956210682127	0.32759324897459	0.764045448703985
GO:0042054	histone methyltransferase activity	14/3388	67/18639	0.208955223880597	1.14956210682127	0.32759324897459	0.764045448703985
GO:0016798	hydrolase activity, acting on glycosyl bonds	26/3388	130/18639	0.2	1.10029515938607	0.327775789715084	0.764045448703985
GO:0016411	acylglycerol O-acyltransferase activity	7/3388	31/18639	0.225806451612903	1.24226872833911	0.328503414045254	0.764045448703985
GO:0003688	DNA replication origin binding	4/3388	16/18639	0.25	1.37536894923259	0.329264639213914	0.764045448703985
GO:0004708	MAP kinase kinase activity	4/3388	16/18639	0.25	1.37536894923259	0.329264639213914	0.764045448703985
GO:0015923	mannosidase activity	4/3388	16/18639	0.25	1.37536894923259	0.329264639213914	0.764045448703985
GO:0043023	ribosomal large subunit binding	4/3388	16/18639	0.25	1.37536894923259	0.329264639213914	0.764045448703985
GO:0016289	acyl-CoA hydrolase activity	6/3388	26/18639	0.230769230769231	1.26957133775316	0.330369262917472	0.764045448703985
GO:0034237	protein kinase A regulatory subunit binding	6/3388	26/18639	0.230769230769231	1.26957133775316	0.330369262917472	0.764045448703985
GO:0050681	nuclear androgen receptor binding	6/3388	26/18639	0.230769230769231	1.26957133775316	0.330369262917472	0.764045448703985
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	5/3388	21/18639	0.238095238095238	1.30987518974532	0.33100726737331	0.764045448703985
GO:0009931	calcium-dependent protein serine/threonine kinase activity	5/3388	21/18639	0.238095238095238	1.30987518974532	0.33100726737331	0.764045448703985
GO:0019200	carbohydrate kinase activity	5/3388	21/18639	0.238095238095238	1.30987518974532	0.33100726737331	0.764045448703985
GO:0005080	protein kinase C binding	11/3388	52/18639	0.211538461538462	1.16377372627373	0.341058781829641	0.784435198208175
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	11/3388	52/18639	0.211538461538462	1.16377372627373	0.341058781829641	0.784435198208175
GO:0043495	protein-membrane adaptor activity	10/3388	47/18639	0.212765957446809	1.17052676530433	0.345788749036372	0.793896450550529
GO:0042277	peptide binding	48/3388	249/18639	0.192771084337349	1.06052545482995	0.350088006341584	0.800733351208605
GO:0008307	structural constituent of muscle	9/3388	42/18639	0.214285714285714	1.17888767077079	0.350631684846004	0.800733351208605
GO:0019894	kinesin binding	9/3388	42/18639	0.214285714285714	1.17888767077079	0.350631684846004	0.800733351208605
GO:0019213	deacetylase activity	8/3388	37/18639	0.216216216216216	1.18950828041737	0.355568785504909	0.810570965894377
GO:0070717	poly-purine tract binding	7/3388	32/18639	0.21875	1.20344783057851	0.360559041928649	0.820494780925971
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	6/3388	27/18639	0.222222222222222	1.22255017709563	0.365515943448493	0.824836515794726
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	6/3388	27/18639	0.222222222222222	1.22255017709563	0.365515943448493	0.824836515794726
GO:0008146	sulfotransferase activity	11/3388	53/18639	0.207547169811321	1.14181573143837	0.365904742359901	0.824836515794726
GO:1901505	carbohydrate derivative transmembrane transporter activity	11/3388	53/18639	0.207547169811321	1.14181573143837	0.365904742359901	0.824836515794726
GO:0046972	histone H4K16 acetyltransferase activity	5/3388	22/18639	0.227272727272727	1.25033540839326	0.370252151908242	0.824836515794726
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	35/3388	181/18639	0.193370165745856	1.06382128669924	0.371491694491243	0.824836515794726
GO:0004550	nucleoside diphosphate kinase activity	4/3388	17/18639	0.235294117647059	1.29446489339537	0.374329090894733	0.824836515794726
GO:0008429	phosphatidylethanolamine binding	4/3388	17/18639	0.235294117647059	1.29446489339537	0.374329090894733	0.824836515794726
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	4/3388	17/18639	0.235294117647059	1.29446489339537	0.374329090894733	0.824836515794726
GO:0048038	quinone binding	4/3388	17/18639	0.235294117647059	1.29446489339537	0.374329090894733	0.824836515794726
GO:0070403	NAD+ binding	4/3388	17/18639	0.235294117647059	1.29446489339537	0.374329090894733	0.824836515794726
GO:0004000	adenosine deaminase activity	3/3388	12/18639	0.25	1.37536894923259	0.376555800688896	0.824836515794726
GO:0008179	adenylate cyclase binding	3/3388	12/18639	0.25	1.37536894923259	0.376555800688896	0.824836515794726
GO:0016208	AMP binding	3/3388	12/18639	0.25	1.37536894923259	0.376555800688896	0.824836515794726
GO:0035197	siRNA binding	3/3388	12/18639	0.25	1.37536894923259	0.376555800688896	0.824836515794726
GO:0035497	cAMP response element binding	3/3388	12/18639	0.25	1.37536894923259	0.376555800688896	0.824836515794726
GO:0045295	gamma-catenin binding	3/3388	12/18639	0.25	1.37536894923259	0.376555800688896	0.824836515794726
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	3/3388	12/18639	0.25	1.37536894923259	0.376555800688896	0.824836515794726
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	3/3388	12/18639	0.25	1.37536894923259	0.376555800688896	0.824836515794726
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	3/3388	12/18639	0.25	1.37536894923259	0.376555800688896	0.824836515794726
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	3/3388	12/18639	0.25	1.37536894923259	0.376555800688896	0.824836515794726
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	3/3388	12/18639	0.25	1.37536894923259	0.376555800688896	0.824836515794726
GO:0045309	protein phosphorylated amino acid binding	12/3388	59/18639	0.203389830508475	1.11894422988414	0.383905287839505	0.839507658297593
GO:0003714	transcription corepressor activity	39/3388	204/18639	0.191176470588235	1.05175272588374	0.391041510623655	0.853663501158081
GO:0071889	14-3-3 protein binding	7/3388	33/18639	0.212121212121212	1.16697971450038	0.392843268470525	0.856145735685341
GO:0005543	phospholipid binding	93/3388	497/18639	0.187122736418511	1.02945120546181	0.395219184080497	0.859868765364326
GO:0120013	lipid transfer activity	13/3388	65/18639	0.2	1.10029515938607	0.40018809495993	0.869211241666761
GO:0017022	myosin binding	15/3388	76/18639	0.197368421052632	1.08581759149941	0.407387048960637	0.882004211072901
GO:0000295	adenine nucleotide transmembrane transporter activity	5/3388	23/18639	0.217391304347826	1.19597299933268	0.40950195514099	0.882004211072901
GO:0070577	lysine-acetylated histone binding	5/3388	23/18639	0.217391304347826	1.19597299933268	0.40950195514099	0.882004211072901
GO:0140103	catalytic activity, acting on a glycoprotein	5/3388	23/18639	0.217391304347826	1.19597299933268	0.40950195514099	0.882004211072901
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	5/3388	23/18639	0.217391304347826	1.19597299933268	0.40950195514099	0.882004211072901
GO:0008308	voltage-gated monoatomic anion channel activity	4/3388	18/18639	0.222222222222222	1.22255017709563	0.419106259029617	0.895205409005219
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	4/3388	18/18639	0.222222222222222	1.22255017709563	0.419106259029617	0.895205409005219
GO:0030228	lipoprotein particle receptor activity	4/3388	18/18639	0.222222222222222	1.22255017709563	0.419106259029617	0.895205409005219
GO:0031690	adrenergic receptor binding	4/3388	18/18639	0.222222222222222	1.22255017709563	0.419106259029617	0.895205409005219
GO:0098641	cadherin binding involved in cell-cell adhesion	4/3388	18/18639	0.222222222222222	1.22255017709563	0.419106259029617	0.895205409005219
GO:0016779	nucleotidyltransferase activity	26/3388	136/18639	0.191176470588235	1.05175272588374	0.422116044928941	0.900141499782245
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	7/3388	34/18639	0.205882352941176	1.13265678172095	0.42513154369895	0.903579914660475
GO:0052866	phosphatidylinositol phosphate phosphatase activity	7/3388	34/18639	0.205882352941176	1.13265678172095	0.42513154369895	0.903579914660475
GO:0005338	nucleotide-sugar transmembrane transporter activity	3/3388	13/18639	0.230769230769231	1.26957133775316	0.429891121760576	0.906218927704781
GO:0008253	5'-nucleotidase activity	3/3388	13/18639	0.230769230769231	1.26957133775316	0.429891121760576	0.906218927704781
GO:0031432	titin binding	3/3388	13/18639	0.230769230769231	1.26957133775316	0.429891121760576	0.906218927704781
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	3/3388	13/18639	0.230769230769231	1.26957133775316	0.429891121760576	0.906218927704781
GO:0140410	monoatomic cation:bicarbonate symporter activity	3/3388	13/18639	0.230769230769231	1.26957133775316	0.429891121760576	0.906218927704781
GO:0042605	peptide antigen binding	9/3388	45/18639	0.2	1.10029515938607	0.43469099918755	0.911581433445818
GO:0035250	UDP-galactosyltransferase activity	6/3388	29/18639	0.206896551724138	1.13823637177869	0.435973729039304	0.911581433445818
GO:0043236	laminin binding	6/3388	29/18639	0.206896551724138	1.13823637177869	0.435973729039304	0.911581433445818
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	6/3388	29/18639	0.206896551724138	1.13823637177869	0.435973729039304	0.911581433445818
GO:0051861	glycolipid binding	6/3388	29/18639	0.206896551724138	1.13823637177869	0.435973729039304	0.911581433445818
GO:0032451	demethylase activity	8/3388	40/18639	0.2	1.10029515938607	0.445332529979218	0.928479380970714
GO:0004622	lysophospholipase activity	5/3388	24/18639	0.208333333333333	1.14614079102715	0.448380570624056	0.928479380970714
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	5/3388	24/18639	0.208333333333333	1.14614079102715	0.448380570624056	0.928479380970714
GO:0030552	cAMP binding	5/3388	24/18639	0.208333333333333	1.14614079102715	0.448380570624056	0.928479380970714
GO:0035035	histone acetyltransferase binding	5/3388	24/18639	0.208333333333333	1.14614079102715	0.448380570624056	0.928479380970714
GO:0140033	acetylation-dependent protein binding	5/3388	24/18639	0.208333333333333	1.14614079102715	0.448380570624056	0.928479380970714
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	4/3388	19/18639	0.210526315789474	1.1582054309327	0.463074018711991	0.9558322693927
GO:0042577	lipid phosphatase activity	4/3388	19/18639	0.210526315789474	1.1582054309327	0.463074018711991	0.9558322693927
GO:0015631	tubulin binding	71/3388	385/18639	0.184415584415584	1.0145578742391	0.4670089178641	0.962411977934337
GO:0031490	chromatin DNA binding	24/3388	128/18639	0.1875	1.03152671192444	0.469004466385305	0.962937043457653
GO:1990841	promoter-specific chromatin binding	13/3388	68/18639	0.191176470588235	1.05175272588374	0.469162606050158	0.962937043457653
GO:0008187	poly-pyrimidine tract binding	6/3388	30/18639	0.2	1.10029515938607	0.470739141056902	0.962937043457653
GO:0015215	nucleotide transmembrane transporter activity	6/3388	30/18639	0.2	1.10029515938607	0.470739141056902	0.962937043457653
GO:0001727	lipid kinase activity	8/3388	41/18639	0.195121951219512	1.07345869208397	0.474986011886768	0.962937043457653
GO:0016877	ligase activity, forming carbon-sulfur bonds	8/3388	41/18639	0.195121951219512	1.07345869208397	0.474986011886768	0.962937043457653
GO:0042287	MHC protein binding	8/3388	41/18639	0.195121951219512	1.07345869208397	0.474986011886768	0.962937043457653
GO:0061650	ubiquitin-like protein conjugating enzyme activity	8/3388	41/18639	0.195121951219512	1.07345869208397	0.474986011886768	0.962937043457653
GO:0003678	DNA helicase activity	14/3388	74/18639	0.189189189189189	1.0408197453652	0.481300324096148	0.962937043457653
GO:0005347	ATP transmembrane transporter activity	3/3388	14/18639	0.214285714285714	1.17888767077079	0.481468521728827	0.962937043457653
GO:0008195	phosphatidate phosphatase activity	3/3388	14/18639	0.214285714285714	1.17888767077079	0.481468521728827	0.962937043457653
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	3/3388	14/18639	0.214285714285714	1.17888767077079	0.481468521728827	0.962937043457653
GO:0031404	chloride ion binding	3/3388	14/18639	0.214285714285714	1.17888767077079	0.481468521728827	0.962937043457653
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	3/3388	14/18639	0.214285714285714	1.17888767077079	0.481468521728827	0.962937043457653
GO:0046030	inositol trisphosphate phosphatase activity	3/3388	14/18639	0.214285714285714	1.17888767077079	0.481468521728827	0.962937043457653
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	3/3388	14/18639	0.214285714285714	1.17888767077079	0.481468521728827	0.962937043457653
GO:0061665	SUMO ligase activity	3/3388	14/18639	0.214285714285714	1.17888767077079	0.481468521728827	0.962937043457653
GO:0070742	C2H2 zinc finger domain binding	3/3388	14/18639	0.214285714285714	1.17888767077079	0.481468521728827	0.962937043457653
GO:0071933	Arp2/3 complex binding	3/3388	14/18639	0.214285714285714	1.17888767077079	0.481468521728827	0.962937043457653
GO:0003707	nuclear steroid receptor activity	5/3388	25/18639	0.2	1.10029515938607	0.486556175525784	0.967105484687053
GO:0008139	nuclear localization sequence binding	5/3388	25/18639	0.2	1.10029515938607	0.486556175525784	0.967105484687053
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	5/3388	25/18639	0.2	1.10029515938607	0.486556175525784	0.967105484687053
GO:0120020	cholesterol transfer activity	5/3388	25/18639	0.2	1.10029515938607	0.486556175525784	0.967105484687053
GO:0001784	phosphotyrosine residue binding	9/3388	47/18639	0.191489361702128	1.0534740887739	0.490300424774939	0.971549149400186
GO:0140938	histone H3 methyltransferase activity	9/3388	47/18639	0.191489361702128	1.0534740887739	0.490300424774939	0.971549149400186
GO:0016279	protein-lysine N-methyltransferase activity	13/3388	69/18639	0.188405797101449	1.03650993275499	0.491959420735272	0.973339068981613
GO:0005246	calcium channel regulator activity	10/3388	53/18639	0.188679245283019	1.03801430130761	0.503785677317634	0.994604952008
GO:0016878	acid-thiol ligase activity	6/3388	31/18639	0.193548387096774	1.06480176714781	0.504875715539697	0.994604952008
GO:0010851	cyclase regulator activity	4/3388	20/18639	0.2	1.10029515938607	0.505796772954379	0.994604952008
GO:0140664	ATP-dependent DNA damage sensor activity	4/3388	20/18639	0.2	1.10029515938607	0.505796772954379	0.994604952008
GO:0004722	protein serine/threonine phosphatase activity	19/3388	103/18639	0.184466019417476	1.01483534118133	0.511910716603941	1
GO:0016278	lysine N-methyltransferase activity	13/3388	70/18639	0.185714285714286	1.02170264800135	0.514540110529868	1
GO:0140693	molecular condensate scaffold activity	9/3388	48/18639	0.1875	1.03152671192444	0.517588292050494	1
GO:0022829	wide pore channel activity	7/3388	37/18639	0.189189189189189	1.0408197453652	0.520006888424619	1
GO:0141108	transporter regulator activity	31/3388	170/18639	0.182352941176471	1.00321029238142	0.523616146231801	1
GO:0008143	poly(A) binding	5/3388	26/18639	0.192307692307692	1.0579761147943	0.52374353567062	1
GO:0008157	protein phosphatase 1 binding	5/3388	26/18639	0.192307692307692	1.0579761147943	0.52374353567062	1
GO:0015216	purine nucleotide transmembrane transporter activity	5/3388	26/18639	0.192307692307692	1.0579761147943	0.52374353567062	1
GO:0030507	spectrin binding	5/3388	26/18639	0.192307692307692	1.0579761147943	0.52374353567062	1
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	3/3388	15/18639	0.2	1.10029515938607	0.530705900060934	1
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	3/3388	15/18639	0.2	1.10029515938607	0.530705900060934	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	3/3388	15/18639	0.2	1.10029515938607	0.530705900060934	1
GO:0005523	tropomyosin binding	3/3388	15/18639	0.2	1.10029515938607	0.530705900060934	1
GO:0008252	nucleotidase activity	3/3388	15/18639	0.2	1.10029515938607	0.530705900060934	1
GO:0015929	hexosaminidase activity	3/3388	15/18639	0.2	1.10029515938607	0.530705900060934	1
GO:0033130	acetylcholine receptor binding	3/3388	15/18639	0.2	1.10029515938607	0.530705900060934	1
GO:0061578	K63-linked deubiquitinase activity	3/3388	15/18639	0.2	1.10029515938607	0.530705900060934	1
GO:0140776	protein-containing complex destabilizing activity	3/3388	15/18639	0.2	1.10029515938607	0.530705900060934	1
GO:0051219	phosphoprotein binding	17/3388	93/18639	0.182795698924731	1.00564611341737	0.5321410541967	1
GO:0008378	galactosyltransferase activity	6/3388	32/18639	0.1875	1.03152671192444	0.538179563296093	1
GO:0120015	sterol transfer activity	6/3388	32/18639	0.1875	1.03152671192444	0.538179563296093	1
GO:0004222	metalloendopeptidase activity	20/3388	110/18639	0.181818181818182	1.00026832671461	0.538513213882762	1
GO:0042826	histone deacetylase binding	23/3388	127/18639	0.181102362204724	0.996330262436204	0.544178062411732	1
GO:0035254	glutamate receptor binding	9/3388	49/18639	0.183673469387755	1.01047514637496	0.544382097891755	1
GO:0005123	death receptor binding	4/3388	21/18639	0.19047619047619	1.04790015179626	0.546923715444043	1
GO:0009975	cyclase activity	4/3388	21/18639	0.19047619047619	1.04790015179626	0.546923715444043	1
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	4/3388	21/18639	0.19047619047619	1.04790015179626	0.546923715444043	1
GO:0072542	protein phosphatase activator activity	4/3388	21/18639	0.19047619047619	1.04790015179626	0.546923715444043	1
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	22/3388	122/18639	0.180327868852459	0.992069406003832	0.553612284562363	1
GO:0005178	integrin binding	29/3388	161/18639	0.180124223602484	0.990949056589937	0.554035228032969	1
GO:0004674	protein serine/threonine kinase activity	78/3388	433/18639	0.18013856812933	0.991027972657198	0.555489350903316	1
GO:0070851	growth factor receptor binding	25/3388	139/18639	0.179856115107914	0.989474064196105	0.558182686572077	1
GO:0008266	poly(U) RNA binding	5/3388	27/18639	0.185185185185185	1.01879181424636	0.559704352084741	1
GO:0035255	ionotropic glutamate receptor binding	5/3388	27/18639	0.185185185185185	1.01879181424636	0.559704352084741	1
GO:0030020	extracellular matrix structural constituent conferring tensile strength	8/3388	44/18639	0.181818181818182	1.00026832671461	0.561055401496549	1
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	2/3388	10/18639	0.2	1.10029515938607	0.566730421915721	1
GO:0008140	cAMP response element binding protein binding	2/3388	10/18639	0.2	1.10029515938607	0.566730421915721	1
GO:0008641	ubiquitin-like modifier activating enzyme activity	2/3388	10/18639	0.2	1.10029515938607	0.566730421915721	1
GO:0015658	branched-chain amino acid transmembrane transporter activity	2/3388	10/18639	0.2	1.10029515938607	0.566730421915721	1
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	2/3388	10/18639	0.2	1.10029515938607	0.566730421915721	1
GO:0031419	cobalamin binding	2/3388	10/18639	0.2	1.10029515938607	0.566730421915721	1
GO:0031996	thioesterase binding	2/3388	10/18639	0.2	1.10029515938607	0.566730421915721	1
GO:0035256	G protein-coupled glutamate receptor binding	2/3388	10/18639	0.2	1.10029515938607	0.566730421915721	1
GO:0043295	glutathione binding	2/3388	10/18639	0.2	1.10029515938607	0.566730421915721	1
GO:0050308	sugar-phosphatase activity	2/3388	10/18639	0.2	1.10029515938607	0.566730421915721	1
GO:0051864	histone H3K36 demethylase activity	2/3388	10/18639	0.2	1.10029515938607	0.566730421915721	1
GO:0070739	protein-glutamic acid ligase activity	2/3388	10/18639	0.2	1.10029515938607	0.566730421915721	1
GO:0070740	tubulin-glutamic acid ligase activity	2/3388	10/18639	0.2	1.10029515938607	0.566730421915721	1
GO:0097177	mitochondrial ribosome binding	2/3388	10/18639	0.2	1.10029515938607	0.566730421915721	1
GO:0140940	histone H2A methyltransferase activity	2/3388	10/18639	0.2	1.10029515938607	0.566730421915721	1
GO:1990259	histone H2AQ104 methyltransferase activity	2/3388	10/18639	0.2	1.10029515938607	0.566730421915721	1
GO:1990757	ubiquitin ligase activator activity	2/3388	10/18639	0.2	1.10029515938607	0.566730421915721	1
GO:0140416	transcription regulator inhibitor activity	6/3388	33/18639	0.181818181818182	1.00026832671461	0.570476517701775	1
GO:0016247	channel regulator activity	30/3388	168/18639	0.178571428571429	0.98240639230899	0.574617145156521	1
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	3/3388	16/18639	0.1875	1.03152671192444	0.577192344871785	1
GO:0004707	MAP kinase activity	3/3388	16/18639	0.1875	1.03152671192444	0.577192344871785	1
GO:0005159	insulin-like growth factor receptor binding	3/3388	16/18639	0.1875	1.03152671192444	0.577192344871785	1
GO:0008296	3'-5'-DNA exonuclease activity	3/3388	16/18639	0.1875	1.03152671192444	0.577192344871785	1
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	3/3388	16/18639	0.1875	1.03152671192444	0.577192344871785	1
GO:0016722	oxidoreductase activity, acting on metal ions	3/3388	16/18639	0.1875	1.03152671192444	0.577192344871785	1
GO:0030275	LRR domain binding	3/3388	16/18639	0.1875	1.03152671192444	0.577192344871785	1
GO:0070411	I-SMAD binding	3/3388	16/18639	0.1875	1.03152671192444	0.577192344871785	1
GO:0097027	ubiquitin-protein transferase activator activity	3/3388	16/18639	0.1875	1.03152671192444	0.577192344871785	1
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	3/3388	16/18639	0.1875	1.03152671192444	0.577192344871785	1
GO:0000217	DNA secondary structure binding	7/3388	39/18639	0.179487179487179	0.98744437380801	0.579910529313375	1
GO:0035402	histone H3T11 kinase activity	44/3388	247/18639	0.178137651821862	0.98001998001998	0.585357427967135	1
GO:0008093	cytoskeletal anchor activity	4/3388	22/18639	0.181818181818182	1.00026832671461	0.586184062896443	1
GO:0140517	protein-RNA adaptor activity	4/3388	22/18639	0.181818181818182	1.00026832671461	0.586184062896443	1
GO:0051019	mitogen-activated protein kinase binding	5/3388	28/18639	0.178571428571429	0.98240639230899	0.594246060509429	1
GO:0051959	dynein light intermediate chain binding	5/3388	28/18639	0.178571428571429	0.98240639230899	0.594246060509429	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	6/3388	34/18639	0.176470588235294	0.970848670046531	0.601621869273808	1
GO:0030332	cyclin binding	6/3388	34/18639	0.176470588235294	0.970848670046531	0.601621869273808	1
GO:0106310	protein serine kinase activity	64/3388	361/18639	0.177285318559557	0.975330889206487	0.609877540038586	1
GO:0004620	phospholipase activity	19/3388	109/18639	0.174311926605505	0.958972845336482	0.619095004367452	1
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	3/3388	17/18639	0.176470588235294	0.970848670046531	0.620663042152582	1
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	3/3388	17/18639	0.176470588235294	0.970848670046531	0.620663042152582	1
GO:0016805	dipeptidase activity	3/3388	17/18639	0.176470588235294	0.970848670046531	0.620663042152582	1
GO:0038191	neuropilin binding	3/3388	17/18639	0.176470588235294	0.970848670046531	0.620663042152582	1
GO:0045236	CXCR chemokine receptor binding	3/3388	17/18639	0.176470588235294	0.970848670046531	0.620663042152582	1
GO:0070492	oligosaccharide binding	3/3388	17/18639	0.176470588235294	0.970848670046531	0.620663042152582	1
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	2/3388	11/18639	0.181818181818182	1.00026832671461	0.621061861331289	1
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	2/3388	11/18639	0.181818181818182	1.00026832671461	0.621061861331289	1
GO:0003953	NAD+ nucleosidase activity	2/3388	11/18639	0.181818181818182	1.00026832671461	0.621061861331289	1
GO:0005114	type II transforming growth factor beta receptor binding	2/3388	11/18639	0.181818181818182	1.00026832671461	0.621061861331289	1
GO:0008046	axon guidance receptor activity	2/3388	11/18639	0.181818181818182	1.00026832671461	0.621061861331289	1
GO:0008172	S-methyltransferase activity	2/3388	11/18639	0.181818181818182	1.00026832671461	0.621061861331289	1
GO:0008503	benzodiazepine receptor activity	2/3388	11/18639	0.181818181818182	1.00026832671461	0.621061861331289	1
GO:0015217	ADP transmembrane transporter activity	2/3388	11/18639	0.181818181818182	1.00026832671461	0.621061861331289	1
GO:0019203	carbohydrate phosphatase activity	2/3388	11/18639	0.181818181818182	1.00026832671461	0.621061861331289	1
GO:0032050	clathrin heavy chain binding	2/3388	11/18639	0.181818181818182	1.00026832671461	0.621061861331289	1
GO:0034056	estrogen response element binding	2/3388	11/18639	0.181818181818182	1.00026832671461	0.621061861331289	1
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	2/3388	11/18639	0.181818181818182	1.00026832671461	0.621061861331289	1
GO:0034713	type I transforming growth factor beta receptor binding	2/3388	11/18639	0.181818181818182	1.00026832671461	0.621061861331289	1
GO:0043522	leucine zipper domain binding	2/3388	11/18639	0.181818181818182	1.00026832671461	0.621061861331289	1
GO:0050786	RAGE receptor binding	2/3388	11/18639	0.181818181818182	1.00026832671461	0.621061861331289	1
GO:0070697	activin receptor binding	2/3388	11/18639	0.181818181818182	1.00026832671461	0.621061861331289	1
GO:1900750	oligopeptide binding	2/3388	11/18639	0.181818181818182	1.00026832671461	0.621061861331289	1
GO:0003887	DNA-directed DNA polymerase activity	4/3388	23/18639	0.173913043478261	0.956778399466146	0.623380296108117	1
GO:0005158	insulin receptor binding	4/3388	23/18639	0.173913043478261	0.956778399466146	0.623380296108117	1
GO:0016849	phosphorus-oxygen lyase activity	4/3388	23/18639	0.173913043478261	0.956778399466146	0.623380296108117	1
GO:0099186	structural constituent of postsynapse	4/3388	23/18639	0.173913043478261	0.956778399466146	0.623380296108117	1
GO:0016791	phosphatase activity	48/3388	273/18639	0.175824175824176	0.967292447811928	0.625893074687777	1
GO:0003785	actin monomer binding	5/3388	29/18639	0.172413793103448	0.948530309815576	0.627219462899039	1
GO:0004629	phospholipase C activity	5/3388	29/18639	0.172413793103448	0.948530309815576	0.627219462899039	1
GO:0034061	DNA polymerase activity	6/3388	35/18639	0.171428571428571	0.94311013661663	0.631499401930688	1
GO:0061631	ubiquitin conjugating enzyme activity	6/3388	35/18639	0.171428571428571	0.94311013661663	0.631499401930688	1
GO:0017080	sodium channel regulator activity	7/3388	41/18639	0.170731707317073	0.939276355573473	0.635936776492028	1
GO:0140359	ABC-type transporter activity	8/3388	47/18639	0.170212765957447	0.936421412243463	0.640399841457517	1
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	14/3388	82/18639	0.170731707317073	0.939276355573473	0.646936059509071	1
GO:0005085	guanyl-nucleotide exchange factor activity	40/3388	230/18639	0.173913043478261	0.956778399466146	0.648632642417303	1
GO:0140299	molecular sensor activity	12/3388	71/18639	0.169014084507042	0.929826895255833	0.657603615033911	1
GO:0015295	solute:proton symporter activity	4/3388	24/18639	0.166666666666667	0.916912632821724	0.658380241204929	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	4/3388	24/18639	0.166666666666667	0.916912632821724	0.658380241204929	1
GO:0140612	DNA damage sensor activity	4/3388	24/18639	0.166666666666667	0.916912632821724	0.658380241204929	1
GO:0032452	histone demethylase activity	5/3388	30/18639	0.166666666666667	0.916912632821724	0.658515527267466	1
GO:0098918	structural constituent of synapse	5/3388	30/18639	0.166666666666667	0.916912632821724	0.658515527267466	1
GO:0016854	racemase and epimerase activity	3/3388	18/18639	0.166666666666667	0.916912632821724	0.660974398777175	1
GO:0034185	apolipoprotein binding	3/3388	18/18639	0.166666666666667	0.916912632821724	0.660974398777175	1
GO:0050811	GABA receptor binding	3/3388	18/18639	0.166666666666667	0.916912632821724	0.660974398777175	1
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	3/3388	18/18639	0.166666666666667	0.916912632821724	0.660974398777175	1
GO:1901611	phosphatidylglycerol binding	3/3388	18/18639	0.166666666666667	0.916912632821724	0.660974398777175	1
GO:0004520	DNA endonuclease activity	7/3388	42/18639	0.166666666666667	0.916912632821724	0.662274961081751	1
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	14/3388	83/18639	0.168674698795181	0.927959772976202	0.665641859712227	1
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	42/3388	243/18639	0.172839506172839	0.950872359963269	0.66747518920124	1
GO:0015297	antiporter activity	23/3388	135/18639	0.17037037037037	0.937288469106651	0.669174269980442	1
GO:0004721	phosphoprotein phosphatase activity	30/3388	175/18639	0.171428571428571	0.94311013661663	0.66939000818645	1
GO:0003720	telomerase activity	2/3388	12/18639	0.166666666666667	0.916912632821724	0.669963073459768	1
GO:0004300	enoyl-CoA hydratase activity	2/3388	12/18639	0.166666666666667	0.916912632821724	0.669963073459768	1
GO:0005078	MAP-kinase scaffold activity	2/3388	12/18639	0.166666666666667	0.916912632821724	0.669963073459768	1
GO:0005095	GTPase inhibitor activity	2/3388	12/18639	0.166666666666667	0.916912632821724	0.669963073459768	1
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	2/3388	12/18639	0.166666666666667	0.916912632821724	0.669963073459768	1
GO:0016273	arginine N-methyltransferase activity	2/3388	12/18639	0.166666666666667	0.916912632821724	0.669963073459768	1
GO:0016274	protein-arginine N-methyltransferase activity	2/3388	12/18639	0.166666666666667	0.916912632821724	0.669963073459768	1
GO:0016840	carbon-nitrogen lyase activity	2/3388	12/18639	0.166666666666667	0.916912632821724	0.669963073459768	1
GO:0017166	vinculin binding	2/3388	12/18639	0.166666666666667	0.916912632821724	0.669963073459768	1
GO:0035014	phosphatidylinositol 3-kinase regulator activity	2/3388	12/18639	0.166666666666667	0.916912632821724	0.669963073459768	1
GO:0036009	protein-glutamine N-methyltransferase activity	2/3388	12/18639	0.166666666666667	0.916912632821724	0.669963073459768	1
GO:0070679	inositol 1,4,5 trisphosphate binding	2/3388	12/18639	0.166666666666667	0.916912632821724	0.669963073459768	1
GO:1990459	transferrin receptor binding	2/3388	12/18639	0.166666666666667	0.916912632821724	0.669963073459768	1
GO:0098531	ligand-modulated transcription factor activity	10/3388	60/18639	0.166666666666667	0.916912632821724	0.67099038822311	1
GO:0046982	protein heterodimerization activity	64/3388	369/18639	0.173441734417344	0.954185504074639	0.683100983669536	1
GO:0140789	histone phosphatase activity	23/3388	136/18639	0.169117647058824	0.930396642127926	0.683487211087181	1
GO:0023023	MHC protein complex binding	6/3388	37/18639	0.162162162162162	0.892131210313029	0.687119176932912	1
GO:0030551	cyclic nucleotide binding	6/3388	37/18639	0.162162162162162	0.892131210313029	0.687119176932912	1
GO:0043394	proteoglycan binding	6/3388	37/18639	0.162162162162162	0.892131210313029	0.687119176932912	1
GO:0017147	Wnt-protein binding	5/3388	31/18639	0.161290322580645	0.887334805956507	0.688061644907422	1
GO:0047499	calcium-independent phospholipase A2 activity	5/3388	31/18639	0.161290322580645	0.887334805956507	0.688061644907422	1
GO:0140457	protein demethylase activity	5/3388	31/18639	0.161290322580645	0.887334805956507	0.688061644907422	1
GO:0003779	actin binding	77/3388	443/18639	0.173814898419865	0.956238456802791	0.688700592642263	1
GO:0004676	3-phosphoinositide-dependent protein kinase activity	42/3388	245/18639	0.171428571428571	0.94311013661663	0.688924308723122	1
GO:0004711	ribosomal protein S6 kinase activity	42/3388	245/18639	0.171428571428571	0.94311013661663	0.688924308723122	1
GO:0035175	histone H3S10 kinase activity	42/3388	245/18639	0.171428571428571	0.94311013661663	0.688924308723122	1
GO:0035979	histone H2AXS139 kinase activity	42/3388	245/18639	0.171428571428571	0.94311013661663	0.688924308723122	1
GO:0044022	histone H3S28 kinase activity	42/3388	245/18639	0.171428571428571	0.94311013661663	0.688924308723122	1
GO:0044023	histone H4S1 kinase activity	42/3388	245/18639	0.171428571428571	0.94311013661663	0.688924308723122	1
GO:0044024	histone H2AS1 kinase activity	42/3388	245/18639	0.171428571428571	0.94311013661663	0.688924308723122	1
GO:0044025	histone H2BS14 kinase activity	42/3388	245/18639	0.171428571428571	0.94311013661663	0.688924308723122	1
GO:0072354	histone H3T3 kinase activity	42/3388	245/18639	0.171428571428571	0.94311013661663	0.688924308723122	1
GO:0072371	histone H2AS121 kinase activity	42/3388	245/18639	0.171428571428571	0.94311013661663	0.688924308723122	1
GO:0072518	Rho-dependent protein serine/threonine kinase activity	42/3388	245/18639	0.171428571428571	0.94311013661663	0.688924308723122	1
GO:0140823	histone H2BS36 kinase activity	42/3388	245/18639	0.171428571428571	0.94311013661663	0.688924308723122	1
GO:0140855	histone H3S57 kinase activity	42/3388	245/18639	0.171428571428571	0.94311013661663	0.688924308723122	1
GO:0140995	histone H2A kinase activity	42/3388	245/18639	0.171428571428571	0.94311013661663	0.688924308723122	1
GO:0140997	histone H4 kinase activity	42/3388	245/18639	0.171428571428571	0.94311013661663	0.688924308723122	1
GO:0140998	histone H2B kinase activity	42/3388	245/18639	0.171428571428571	0.94311013661663	0.688924308723122	1
GO:1990244	histone H2AT120 kinase activity	42/3388	245/18639	0.171428571428571	0.94311013661663	0.688924308723122	1
GO:0022840	leak channel activity	3/3388	19/18639	0.157894736842105	0.868654073199528	0.698080720039397	1
GO:0022842	narrow pore channel activity	3/3388	19/18639	0.157894736842105	0.868654073199528	0.698080720039397	1
GO:0030506	ankyrin binding	3/3388	19/18639	0.157894736842105	0.868654073199528	0.698080720039397	1
GO:0004677	DNA-dependent protein kinase activity	42/3388	246/18639	0.170731707317073	0.939276355573473	0.699372797465595	1
GO:0140857	histone H3T45 kinase activity	42/3388	246/18639	0.170731707317073	0.939276355573473	0.699372797465595	1
GO:0035403	histone H3T6 kinase activity	42/3388	247/18639	0.17004048582996	0.935473617291799	0.709630074262724	1
GO:0030170	pyridoxal phosphate binding	9/3388	56/18639	0.160714285714286	0.884165753078091	0.71129382289861	1
GO:0043014	alpha-tubulin binding	7/3388	44/18639	0.159090909090909	0.875234785875282	0.711322542095338	1
GO:0005109	frizzled binding	6/3388	38/18639	0.157894736842105	0.868654073199528	0.712756027450627	1
GO:0032934	sterol binding	11/3388	68/18639	0.161764705882353	0.88994461420932	0.71335621247497	1
GO:0002161	aminoacyl-tRNA editing activity	2/3388	13/18639	0.153846153846154	0.846380891835437	0.713612519223258	1
GO:0003964	RNA-directed DNA polymerase activity	2/3388	13/18639	0.153846153846154	0.846380891835437	0.713612519223258	1
GO:0004465	lipoprotein lipase activity	2/3388	13/18639	0.153846153846154	0.846380891835437	0.713612519223258	1
GO:0004535	poly(A)-specific ribonuclease activity	2/3388	13/18639	0.153846153846154	0.846380891835437	0.713612519223258	1
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	2/3388	13/18639	0.153846153846154	0.846380891835437	0.713612519223258	1
GO:0005542	folic acid binding	2/3388	13/18639	0.153846153846154	0.846380891835437	0.713612519223258	1
GO:0008417	fucosyltransferase activity	2/3388	13/18639	0.153846153846154	0.846380891835437	0.713612519223258	1
GO:0015651	quaternary ammonium group transmembrane transporter activity	2/3388	13/18639	0.153846153846154	0.846380891835437	0.713612519223258	1
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	2/3388	13/18639	0.153846153846154	0.846380891835437	0.713612519223258	1
GO:0035325	Toll-like receptor binding	2/3388	13/18639	0.153846153846154	0.846380891835437	0.713612519223258	1
GO:0039706	co-receptor binding	2/3388	13/18639	0.153846153846154	0.846380891835437	0.713612519223258	1
GO:0043560	insulin receptor substrate binding	2/3388	13/18639	0.153846153846154	0.846380891835437	0.713612519223258	1
GO:0046975	histone H3K36 methyltransferase activity	2/3388	13/18639	0.153846153846154	0.846380891835437	0.713612519223258	1
GO:0070700	BMP receptor binding	2/3388	13/18639	0.153846153846154	0.846380891835437	0.713612519223258	1
GO:0097157	pre-mRNA intronic binding	2/3388	13/18639	0.153846153846154	0.846380891835437	0.713612519223258	1
GO:0140666	annealing activity	2/3388	13/18639	0.153846153846154	0.846380891835437	0.713612519223258	1
GO:0015106	bicarbonate transmembrane transporter activity	5/3388	32/18639	0.15625	0.859605593270366	0.715817585946557	1
GO:0043425	bHLH transcription factor binding	5/3388	32/18639	0.15625	0.859605593270366	0.715817585946557	1
GO:0047498	calcium-dependent phospholipase A2 activity	5/3388	32/18639	0.15625	0.859605593270366	0.715817585946557	1
GO:0004679	AMP-activated protein kinase activity	42/3388	248/18639	0.169354838709677	0.931701546254332	0.719691369832434	1
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	4/3388	26/18639	0.153846153846154	0.846380891835437	0.721538652667079	1
GO:0052742	phosphatidylinositol kinase activity	4/3388	26/18639	0.153846153846154	0.846380891835437	0.721538652667079	1
GO:1901682	sulfur compound transmembrane transporter activity	10/3388	63/18639	0.158730158730159	0.87325012649688	0.731433712759223	1
GO:0070279	vitamin B6 binding	9/3388	57/18639	0.157894736842105	0.868654073199528	0.731552556604209	1
GO:0016408	C-acyltransferase activity	3/3388	20/18639	0.15	0.825221369539551	0.732013181289695	1
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	3/3388	20/18639	0.15	0.825221369539551	0.732013181289695	1
GO:0052745	inositol phosphate phosphatase activity	3/3388	20/18639	0.15	0.825221369539551	0.732013181289695	1
GO:0140939	histone H4 methyltransferase activity	3/3388	20/18639	0.15	0.825221369539551	0.732013181289695	1
GO:0033192	calmodulin-dependent protein phosphatase activity	13/3388	81/18639	0.160493827160494	0.882952905680178	0.733481764555241	1
GO:0140791	histone H2AXS140 phosphatase activity	13/3388	81/18639	0.160493827160494	0.882952905680178	0.733481764555241	1
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	13/3388	81/18639	0.160493827160494	0.882952905680178	0.733481764555241	1
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	13/3388	81/18639	0.160493827160494	0.882952905680178	0.733481764555241	1
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	13/3388	81/18639	0.160493827160494	0.882952905680178	0.733481764555241	1
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	13/3388	81/18639	0.160493827160494	0.882952905680178	0.733481764555241	1
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	13/3388	81/18639	0.160493827160494	0.882952905680178	0.733481764555241	1
GO:1990439	MAP kinase serine/threonine phosphatase activity	13/3388	81/18639	0.160493827160494	0.882952905680178	0.733481764555241	1
GO:0019239	deaminase activity	5/3388	33/18639	0.151515151515152	0.83355693892884	0.741771348133125	1
GO:0030296	protein tyrosine kinase activator activity	5/3388	33/18639	0.151515151515152	0.83355693892884	0.741771348133125	1
GO:0016405	CoA-ligase activity	4/3388	27/18639	0.148148148148148	0.815033451397088	0.749683748420529	1
GO:0023026	MHC class II protein complex binding	4/3388	27/18639	0.148148148148148	0.815033451397088	0.749683748420529	1
GO:0033549	MAP kinase phosphatase activity	13/3388	82/18639	0.158536585365854	0.872185187318225	0.749787477100171	1
GO:0004705	JUN kinase activity	2/3388	14/18639	0.142857142857143	0.785925113847192	0.752303185472329	1
GO:0005313	L-glutamate transmembrane transporter activity	2/3388	14/18639	0.142857142857143	0.785925113847192	0.752303185472329	1
GO:0005545	1-phosphatidylinositol binding	2/3388	14/18639	0.142857142857143	0.785925113847192	0.752303185472329	1
GO:0008191	metalloendopeptidase inhibitor activity	2/3388	14/18639	0.142857142857143	0.785925113847192	0.752303185472329	1
GO:0008559	ABC-type xenobiotic transporter activity	2/3388	14/18639	0.142857142857143	0.785925113847192	0.752303185472329	1
GO:0015926	glucosidase activity	2/3388	14/18639	0.142857142857143	0.785925113847192	0.752303185472329	1
GO:0032036	myosin heavy chain binding	2/3388	14/18639	0.142857142857143	0.785925113847192	0.752303185472329	1
GO:1901612	cardiolipin binding	2/3388	14/18639	0.142857142857143	0.785925113847192	0.752303185472329	1
GO:0003774	cytoskeletal motor activity	25/3388	153/18639	0.163398692810458	0.898933953746788	0.753438410551581	1
GO:0005200	structural constituent of cytoskeleton	18/3388	112/18639	0.160714285714286	0.884165753078091	0.754587322616125	1
GO:0004180	carboxypeptidase activity	7/3388	46/18639	0.152173913043478	0.837181099532878	0.755350715947646	1
GO:0016298	lipase activity	21/3388	130/18639	0.161538461538462	0.888699936427209	0.758773515054023	1
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	21/3388	130/18639	0.161538461538462	0.888699936427209	0.758773515054023	1
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	3/3388	21/18639	0.142857142857143	0.785925113847192	0.762861425597303	1
GO:0035613	RNA stem-loop binding	3/3388	21/18639	0.142857142857143	0.785925113847192	0.762861425597303	1
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	14/3388	89/18639	0.157303370786517	0.865400687157582	0.765500448700605	1
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	14/3388	89/18639	0.157303370786517	0.865400687157582	0.765500448700605	1
GO:0015020	glucuronosyltransferase activity	5/3388	34/18639	0.147058823529412	0.809040558372109	0.765935051384732	1
GO:0008017	microtubule binding	46/3388	276/18639	0.166666666666667	0.916912632821724	0.766247459374099	1
GO:0099106	ion channel regulator activity	26/3388	160/18639	0.1625	0.893989817001181	0.766613302077214	1
GO:0004879	nuclear receptor activity	9/3388	59/18639	0.152542372881356	0.839208172413103	0.769132070227043	1
GO:0045499	chemorepellent activity	4/3388	28/18639	0.142857142857143	0.785925113847192	0.775590029739045	1
GO:0140793	histone H2AXY142 phosphatase activity	14/3388	90/18639	0.155555555555556	0.855785123966942	0.779965759306642	1
GO:0005496	steroid binding	17/3388	108/18639	0.157407407407407	0.865973042109406	0.780310127117265	1
GO:0017018	myosin phosphatase activity	13/3388	84/18639	0.154761904761905	0.851418873334458	0.780360093448548	1
GO:0061134	peptidase regulator activity	37/3388	226/18639	0.163716814159292	0.900684090647888	0.784696211349551	1
GO:0004089	carbonate dehydratase activity	2/3388	15/18639	0.133333333333333	0.733530106257379	0.786395075535621	1
GO:0017081	chloride channel regulator activity	2/3388	15/18639	0.133333333333333	0.733530106257379	0.786395075535621	1
GO:0031005	filamin binding	2/3388	15/18639	0.133333333333333	0.733530106257379	0.786395075535621	1
GO:0047372	monoacylglycerol lipase activity	2/3388	15/18639	0.133333333333333	0.733530106257379	0.786395075535621	1
GO:0048531	beta-1,3-galactosyltransferase activity	2/3388	15/18639	0.133333333333333	0.733530106257379	0.786395075535621	1
GO:0140161	monocarboxylate:sodium symporter activity	2/3388	15/18639	0.133333333333333	0.733530106257379	0.786395075535621	1
GO:0004623	phospholipase A2 activity	5/3388	35/18639	0.142857142857143	0.785925113847192	0.788340992960405	1
GO:0051015	actin filament binding	34/3388	209/18639	0.162679425837321	0.894976923902544	0.78913321618246	1
GO:0015485	cholesterol binding	8/3388	54/18639	0.148148148148148	0.815033451397088	0.789789746796363	1
GO:0004407	histone deacetylase activity	3/3388	22/18639	0.136363636363636	0.750201245035956	0.790757851286913	1
GO:0015377	chloride:monoatomic cation symporter activity	3/3388	22/18639	0.136363636363636	0.750201245035956	0.790757851286913	1
GO:0031683	G-protein beta/gamma-subunit complex binding	3/3388	22/18639	0.136363636363636	0.750201245035956	0.790757851286913	1
GO:0033558	protein lysine deacetylase activity	3/3388	22/18639	0.136363636363636	0.750201245035956	0.790757851286913	1
GO:0017124	SH3 domain binding	18/3388	115/18639	0.156521739130435	0.861100559519532	0.793158437043633	1
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	7/3388	48/18639	0.145833333333333	0.802298553719008	0.794333820776382	1
GO:0050840	extracellular matrix binding	10/3388	67/18639	0.149253731343284	0.821115790586618	0.79978915618884	1
GO:0008234	cysteine-type peptidase activity	30/3388	187/18639	0.160427807486631	0.882589700042301	0.802522611241443	1
GO:0046906	tetrapyrrole binding	24/3388	152/18639	0.157894736842105	0.868654073199528	0.806989207113709	1
GO:0004190	aspartic-type endopeptidase activity	5/3388	36/18639	0.138888888888889	0.76409386068477	0.809037945550061	1
GO:0045505	dynein intermediate chain binding	5/3388	36/18639	0.138888888888889	0.76409386068477	0.809037945550061	1
GO:0042578	phosphoric ester hydrolase activity	60/3388	363/18639	0.165289256198347	0.909334842467825	0.812772058898709	1
GO:0005548	phospholipid transporter activity	10/3388	68/18639	0.147058823529412	0.809040558372109	0.814691387863646	1
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	2/3388	16/18639	0.125	0.687684474616293	0.816281179916169	1
GO:0005324	long-chain fatty acid transmembrane transporter activity	2/3388	16/18639	0.125	0.687684474616293	0.816281179916169	1
GO:0015378	sodium:chloride symporter activity	2/3388	16/18639	0.125	0.687684474616293	0.816281179916169	1
GO:0015385	sodium:proton antiporter activity	2/3388	16/18639	0.125	0.687684474616293	0.816281179916169	1
GO:0019841	retinol binding	2/3388	16/18639	0.125	0.687684474616293	0.816281179916169	1
GO:0022858	alanine transmembrane transporter activity	2/3388	16/18639	0.125	0.687684474616293	0.816281179916169	1
GO:0031435	mitogen-activated protein kinase kinase kinase binding	2/3388	16/18639	0.125	0.687684474616293	0.816281179916169	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	2/3388	16/18639	0.125	0.687684474616293	0.816281179916169	1
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/3388	16/18639	0.125	0.687684474616293	0.816281179916169	1
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	2/3388	16/18639	0.125	0.687684474616293	0.816281179916169	1
GO:0048156	tau protein binding	6/3388	43/18639	0.13953488372093	0.767647785618187	0.818864810921543	1
GO:0001965	G-protein alpha-subunit binding	4/3388	30/18639	0.133333333333333	0.733530106257379	0.82099298092052	1
GO:0033612	receptor serine/threonine kinase binding	4/3388	30/18639	0.133333333333333	0.733530106257379	0.82099298092052	1
GO:0070566	adenylyltransferase activity	4/3388	30/18639	0.133333333333333	0.733530106257379	0.82099298092052	1
GO:0001618	virus receptor activity	12/3388	81/18639	0.148148148148148	0.815033451397088	0.823114884640792	1
GO:0020037	heme binding	22/3388	142/18639	0.154929577464789	0.85234132065118	0.826288357815314	1
GO:0070001	aspartic-type peptidase activity	5/3388	37/18639	0.135135135135135	0.743442675260857	0.828087753146491	1
GO:0032813	tumor necrosis factor receptor superfamily binding	7/3388	50/18639	0.14	0.770206611570248	0.828420576882789	1
GO:0042562	hormone binding	14/3388	94/18639	0.148936170212766	0.81936873571303	0.831538718800927	1
GO:0140272	exogenous protein binding	12/3388	82/18639	0.146341463414634	0.805094019062977	0.835685297362041	1
GO:0004806	triacylglycerol lipase activity	3/3388	24/18639	0.125	0.687684474616293	0.83836223361499	1
GO:0050699	WW domain binding	3/3388	24/18639	0.125	0.687684474616293	0.83836223361499	1
GO:0070840	dynein complex binding	3/3388	24/18639	0.125	0.687684474616293	0.83836223361499	1
GO:0030246	carbohydrate binding	45/3388	280/18639	0.160714285714286	0.884165753078091	0.841077845866134	1
GO:0005092	GDP-dissociation inhibitor activity	2/3388	17/18639	0.117647058823529	0.647232446697687	0.842363598284647	1
GO:0008569	minus-end-directed microtubule motor activity	2/3388	17/18639	0.117647058823529	0.647232446697687	0.842363598284647	1
GO:0015278	intracellularly gated calcium channel activity	2/3388	17/18639	0.117647058823529	0.647232446697687	0.842363598284647	1
GO:0030169	low-density lipoprotein particle binding	2/3388	17/18639	0.117647058823529	0.647232446697687	0.842363598284647	1
GO:0030548	acetylcholine receptor regulator activity	2/3388	17/18639	0.117647058823529	0.647232446697687	0.842363598284647	1
GO:0000146	microfilament motor activity	5/3388	38/18639	0.131578947368421	0.72387839433294	0.845562257039803	1
GO:0140996	histone H3 kinase activity	58/3388	357/18639	0.162464985994398	0.893797188296806	0.847387625082906	1
GO:0008009	chemokine activity	6/3388	45/18639	0.133333333333333	0.733530106257379	0.8515182220912	1
GO:0004709	MAP kinase kinase kinase activity	3/3388	25/18639	0.12	0.660177095631641	0.858442269835085	1
GO:0005537	D-mannose binding	3/3388	25/18639	0.12	0.660177095631641	0.858442269835085	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	3/3388	25/18639	0.12	0.660177095631641	0.858442269835085	1
GO:0015645	fatty acid ligase activity	3/3388	25/18639	0.12	0.660177095631641	0.858442269835085	1
GO:0042974	nuclear retinoic acid receptor binding	3/3388	25/18639	0.12	0.660177095631641	0.858442269835085	1
GO:0120515	fatty acid-CoA ligase activity	3/3388	25/18639	0.12	0.660177095631641	0.858442269835085	1
GO:0141003	histone H2AX kinase activity	57/3388	354/18639	0.161016949152542	0.885830848658275	0.863240257111777	1
GO:0035173	histone kinase activity	58/3388	360/18639	0.161111111111111	0.886348878394333	0.864034126641362	1
GO:0000400	four-way junction DNA binding	2/3388	18/18639	0.111111111111111	0.611275088547816	0.865037248223081	1
GO:0004706	JUN kinase kinase kinase activity	2/3388	18/18639	0.111111111111111	0.611275088547816	0.865037248223081	1
GO:0004970	glutamate-gated receptor activity	2/3388	18/18639	0.111111111111111	0.611275088547816	0.865037248223081	1
GO:0008525	phosphatidylcholine transporter activity	2/3388	18/18639	0.111111111111111	0.611275088547816	0.865037248223081	1
GO:0015172	acidic amino acid transmembrane transporter activity	2/3388	18/18639	0.111111111111111	0.611275088547816	0.865037248223081	1
GO:0015373	monoatomic anion:sodium symporter activity	2/3388	18/18639	0.111111111111111	0.611275088547816	0.865037248223081	1
GO:0017128	phospholipid scramblase activity	2/3388	18/18639	0.111111111111111	0.611275088547816	0.865037248223081	1
GO:0099602	neurotransmitter receptor regulator activity	2/3388	18/18639	0.111111111111111	0.611275088547816	0.865037248223081	1
GO:0004382	GDP phosphatase activity	1/3388	10/18639	0.1	0.550147579693034	0.865561359285848	1
GO:0005031	tumor necrosis factor receptor activity	1/3388	10/18639	0.1	0.550147579693034	0.865561359285848	1
GO:0005131	growth hormone receptor binding	1/3388	10/18639	0.1	0.550147579693034	0.865561359285848	1
GO:0005337	nucleoside transmembrane transporter activity	1/3388	10/18639	0.1	0.550147579693034	0.865561359285848	1
GO:0005345	purine nucleobase transmembrane transporter activity	1/3388	10/18639	0.1	0.550147579693034	0.865561359285848	1
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	1/3388	10/18639	0.1	0.550147579693034	0.865561359285848	1
GO:0008519	ammonium channel activity	1/3388	10/18639	0.1	0.550147579693034	0.865561359285848	1
GO:0015643	toxic substance binding	1/3388	10/18639	0.1	0.550147579693034	0.865561359285848	1
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/3388	10/18639	0.1	0.550147579693034	0.865561359285848	1
GO:0016303	1-phosphatidylinositol-3-kinase activity	1/3388	10/18639	0.1	0.550147579693034	0.865561359285848	1
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/3388	10/18639	0.1	0.550147579693034	0.865561359285848	1
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/3388	10/18639	0.1	0.550147579693034	0.865561359285848	1
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/3388	10/18639	0.1	0.550147579693034	0.865561359285848	1
GO:0070097	delta-catenin binding	1/3388	10/18639	0.1	0.550147579693034	0.865561359285848	1
GO:0140135	mechanosensitive monoatomic cation channel activity	1/3388	10/18639	0.1	0.550147579693034	0.865561359285848	1
GO:1905394	retromer complex binding	1/3388	10/18639	0.1	0.550147579693034	0.865561359285848	1
GO:0030276	clathrin binding	6/3388	46/18639	0.130434782608696	0.71758379959961	0.865943348012733	1
GO:0030695	GTPase regulator activity	80/3388	489/18639	0.16359918200409	0.900036940193103	0.868330696165936	1
GO:0005544	calcium-dependent phospholipid binding	7/3388	53/18639	0.132075471698113	0.726610010915328	0.870996988408181	1
GO:0038064	collagen receptor activity	7/3388	53/18639	0.132075471698113	0.726610010915328	0.870996988408181	1
GO:0060589	nucleoside-triphosphatase regulator activity	80/3388	490/18639	0.163265306122449	0.898200130111076	0.872771028352721	1
GO:0004725	protein tyrosine phosphatase activity	14/3388	98/18639	0.142857142857143	0.785925113847192	0.873458762537284	1
GO:0043178	alcohol binding	13/3388	92/18639	0.141304347826087	0.777382449566244	0.876118541616799	1
GO:0004112	cyclic-nucleotide phosphodiesterase activity	3/3388	26/18639	0.115384615384615	0.634785668876578	0.876299263378738	1
GO:0004435	phosphatidylinositol phospholipase C activity	3/3388	26/18639	0.115384615384615	0.634785668876578	0.876299263378738	1
GO:0005112	Notch binding	3/3388	26/18639	0.115384615384615	0.634785668876578	0.876299263378738	1
GO:0005160	transforming growth factor beta receptor binding	3/3388	26/18639	0.115384615384615	0.634785668876578	0.876299263378738	1
GO:0051139	metal cation:proton antiporter activity	3/3388	26/18639	0.115384615384615	0.634785668876578	0.876299263378738	1
GO:0070412	R-SMAD binding	3/3388	26/18639	0.115384615384615	0.634785668876578	0.876299263378738	1
GO:0019838	growth factor binding	20/3388	136/18639	0.147058823529412	0.809040558372109	0.880057053300852	1
GO:0005229	intracellularly calcium-gated chloride channel activity	2/3388	19/18639	0.105263157894737	0.579102715466352	0.884679192715279	1
GO:0015245	fatty acid transmembrane transporter activity	2/3388	19/18639	0.105263157894737	0.579102715466352	0.884679192715279	1
GO:0042834	peptidoglycan binding	2/3388	19/18639	0.105263157894737	0.579102715466352	0.884679192715279	1
GO:0043395	heparan sulfate proteoglycan binding	2/3388	19/18639	0.105263157894737	0.579102715466352	0.884679192715279	1
GO:0141147	intracellularly calcium-gated channel activity	2/3388	19/18639	0.105263157894737	0.579102715466352	0.884679192715279	1
GO:0008081	phosphoric diester hydrolase activity	12/3388	87/18639	0.137931034482759	0.758824247852461	0.888505011340963	1
GO:0140828	metal cation:monoatomic cation antiporter activity	5/3388	41/18639	0.121951219512195	0.670911682552481	0.889347401107865	1
GO:0005201	extracellular matrix structural constituent	25/3388	168/18639	0.148809523809524	0.818671993590825	0.889707183463643	1
GO:0000099	sulfur amino acid transmembrane transporter activity	1/3388	11/18639	0.0909090909090909	0.500134163357304	0.890011309081304	1
GO:0002162	dystroglycan binding	1/3388	11/18639	0.0909090909090909	0.500134163357304	0.890011309081304	1
GO:0015173	aromatic amino acid transmembrane transporter activity	1/3388	11/18639	0.0909090909090909	0.500134163357304	0.890011309081304	1
GO:0015205	nucleobase transmembrane transporter activity	1/3388	11/18639	0.0909090909090909	0.500134163357304	0.890011309081304	1
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/3388	11/18639	0.0909090909090909	0.500134163357304	0.890011309081304	1
GO:0016594	glycine binding	1/3388	11/18639	0.0909090909090909	0.500134163357304	0.890011309081304	1
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	1/3388	11/18639	0.0909090909090909	0.500134163357304	0.890011309081304	1
GO:0019215	intermediate filament binding	1/3388	11/18639	0.0909090909090909	0.500134163357304	0.890011309081304	1
GO:0042608	T cell receptor binding	1/3388	11/18639	0.0909090909090909	0.500134163357304	0.890011309081304	1
GO:0045294	alpha-catenin binding	1/3388	11/18639	0.0909090909090909	0.500134163357304	0.890011309081304	1
GO:0047676	arachidonate-CoA ligase activity	1/3388	11/18639	0.0909090909090909	0.500134163357304	0.890011309081304	1
GO:0050998	nitric-oxide synthase binding	1/3388	11/18639	0.0909090909090909	0.500134163357304	0.890011309081304	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/3388	11/18639	0.0909090909090909	0.500134163357304	0.890011309081304	1
GO:0180030	inositol phosphate kinase activity	1/3388	11/18639	0.0909090909090909	0.500134163357304	0.890011309081304	1
GO:0004683	calcium/calmodulin-dependent protein kinase activity	3/3388	27/18639	0.111111111111111	0.611275088547816	0.892126202748514	1
GO:0001217	DNA-binding transcription repressor activity	43/3388	278/18639	0.154676258992806	0.85094769520865	0.897816180981068	1
GO:0042056	chemoattractant activity	5/3388	42/18639	0.119047619047619	0.65493759487266	0.901350675171332	1
GO:0005326	neurotransmitter transmembrane transporter activity	2/3388	20/18639	0.1	0.550147579693034	0.901642082873677	1
GO:0019783	ubiquitin-like protein peptidase activity	18/3388	127/18639	0.141732283464567	0.779736727123986	0.904675071131841	1
GO:0005242	inward rectifier potassium channel activity	3/3388	28/18639	0.107142857142857	0.589443835385394	0.90611054350965	1
GO:0141052	histone H3 demethylase activity	3/3388	28/18639	0.107142857142857	0.589443835385394	0.90611054350965	1
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	41/3388	268/18639	0.152985074626866	0.841643685351284	0.907230334750367	1
GO:0035401	histone H3Y41 kinase activity	16/3388	115/18639	0.139130434782609	0.765422719572917	0.908690784883339	1
GO:0140801	histone H2AXY142 kinase activity	16/3388	115/18639	0.139130434782609	0.765422719572917	0.908690784883339	1
GO:0004126	cytidine deaminase activity	1/3388	12/18639	0.0833333333333333	0.458456316410862	0.910015694137807	1
GO:0005247	voltage-gated chloride channel activity	1/3388	12/18639	0.0833333333333333	0.458456316410862	0.910015694137807	1
GO:0005436	sodium:phosphate symporter activity	1/3388	12/18639	0.0833333333333333	0.458456316410862	0.910015694137807	1
GO:0008504	monoamine transmembrane transporter activity	1/3388	12/18639	0.0833333333333333	0.458456316410862	0.910015694137807	1
GO:0015368	calcium:monoatomic cation antiporter activity	1/3388	12/18639	0.0833333333333333	0.458456316410862	0.910015694137807	1
GO:0034452	dynactin binding	1/3388	12/18639	0.0833333333333333	0.458456316410862	0.910015694137807	1
GO:0035259	nuclear glucocorticoid receptor binding	1/3388	12/18639	0.0833333333333333	0.458456316410862	0.910015694137807	1
GO:0042301	phosphate ion binding	1/3388	12/18639	0.0833333333333333	0.458456316410862	0.910015694137807	1
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/3388	12/18639	0.0833333333333333	0.458456316410862	0.910015694137807	1
GO:0070410	co-SMAD binding	1/3388	12/18639	0.0833333333333333	0.458456316410862	0.910015694137807	1
GO:0097677	STAT family protein binding	1/3388	12/18639	0.0833333333333333	0.458456316410862	0.910015694137807	1
GO:0140829	bicarbonate:monoatomic anion antiporter activity	1/3388	12/18639	0.0833333333333333	0.458456316410862	0.910015694137807	1
GO:0140900	chloride:bicarbonate antiporter activity	1/3388	12/18639	0.0833333333333333	0.458456316410862	0.910015694137807	1
GO:1990247	N6-methyladenosine-containing RNA reader activity	1/3388	12/18639	0.0833333333333333	0.458456316410862	0.910015694137807	1
GO:1990817	poly(A) RNA polymerase activity	1/3388	12/18639	0.0833333333333333	0.458456316410862	0.910015694137807	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	9/3388	70/18639	0.128571428571429	0.707332602462473	0.910162154924687	1
GO:0061135	endopeptidase regulator activity	27/3388	184/18639	0.146739130434783	0.807281774549561	0.911882371914309	1
GO:0005007	fibroblast growth factor receptor activity	6/3388	50/18639	0.12	0.660177095631641	0.91245923674302	1
GO:0044390	ubiquitin-like protein conjugating enzyme binding	4/3388	36/18639	0.111111111111111	0.611275088547816	0.913761222948519	1
GO:0008373	sialyltransferase activity	2/3388	21/18639	0.0952380952380952	0.523950075898128	0.916250573113296	1
GO:0015125	bile acid transmembrane transporter activity	2/3388	21/18639	0.0952380952380952	0.523950075898128	0.916250573113296	1
GO:0015174	basic amino acid transmembrane transporter activity	2/3388	21/18639	0.0952380952380952	0.523950075898128	0.916250573113296	1
GO:0036122	BMP binding	2/3388	21/18639	0.0952380952380952	0.523950075898128	0.916250573113296	1
GO:0051010	microtubule plus-end binding	2/3388	21/18639	0.0952380952380952	0.523950075898128	0.916250573113296	1
GO:0051428	peptide hormone receptor binding	2/3388	21/18639	0.0952380952380952	0.523950075898128	0.916250573113296	1
GO:0004181	metallocarboxypeptidase activity	3/3388	29/18639	0.103448275862069	0.569118185889346	0.918431453864597	1
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	3/3388	29/18639	0.103448275862069	0.569118185889346	0.918431453864597	1
GO:0097472	cyclin-dependent protein kinase activity	3/3388	29/18639	0.103448275862069	0.569118185889346	0.918431453864597	1
GO:0099604	ligand-gated calcium channel activity	3/3388	29/18639	0.103448275862069	0.569118185889346	0.918431453864597	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	12/3388	91/18639	0.131868131868132	0.725469335858946	0.920011198101352	1
GO:0005021	vascular endothelial growth factor receptor activity	6/3388	51/18639	0.117647058823529	0.647232446697687	0.921625775380526	1
GO:0030547	signaling receptor inhibitor activity	5/3388	44/18639	0.113636363636364	0.62516770419663	0.921993682106304	1
GO:0038024	cargo receptor activity	8/3388	65/18639	0.123076923076923	0.67710471346835	0.92382373988431	1
GO:0008083	growth factor activity	23/3388	162/18639	0.141975308641975	0.781073724255542	0.92604538890257	1
GO:0004993	G protein-coupled serotonin receptor activity	1/3388	13/18639	0.0769230769230769	0.423190445917719	0.926382625380686	1
GO:0005035	death receptor activity	1/3388	13/18639	0.0769230769230769	0.423190445917719	0.926382625380686	1
GO:0008035	high-density lipoprotein particle binding	1/3388	13/18639	0.0769230769230769	0.423190445917719	0.926382625380686	1
GO:0017154	semaphorin receptor activity	1/3388	13/18639	0.0769230769230769	0.423190445917719	0.926382625380686	1
GO:0035673	oligopeptide transmembrane transporter activity	1/3388	13/18639	0.0769230769230769	0.423190445917719	0.926382625380686	1
GO:0046974	histone H3K9 methyltransferase activity	1/3388	13/18639	0.0769230769230769	0.423190445917719	0.926382625380686	1
GO:0061459	L-arginine transmembrane transporter activity	1/3388	13/18639	0.0769230769230769	0.423190445917719	0.926382625380686	1
GO:0071714	icosanoid transmembrane transporter activity	1/3388	13/18639	0.0769230769230769	0.423190445917719	0.926382625380686	1
GO:0089720	caspase binding	1/3388	13/18639	0.0769230769230769	0.423190445917719	0.926382625380686	1
GO:1901338	catecholamine binding	1/3388	13/18639	0.0769230769230769	0.423190445917719	0.926382625380686	1
GO:0004175	endopeptidase activity	63/3388	405/18639	0.155555555555556	0.855785123966942	0.928427756206387	1
GO:0005262	calcium channel activity	18/3388	131/18639	0.137404580152672	0.755927972097299	0.928560673965911	1
GO:0008970	phospholipase A1 activity	2/3388	22/18639	0.0909090909090909	0.500134163357304	0.928799845295934	1
GO:0140784	metal ion sensor activity	2/3388	22/18639	0.0909090909090909	0.500134163357304	0.928799845295934	1
GO:0005516	calmodulin binding	30/3388	207/18639	0.144927536231884	0.797315332888455	0.93294600936173	1
GO:0042887	amide transmembrane transporter activity	4/3388	38/18639	0.105263157894737	0.579102715466352	0.933391018768357	1
GO:0005126	cytokine receptor binding	41/3388	275/18639	0.149090909090909	0.820220027905978	0.935371208055921	1
GO:0004714	transmembrane receptor protein tyrosine kinase activity	7/3388	60/18639	0.116666666666667	0.641838842975207	0.937297871445674	1
GO:0005164	tumor necrosis factor receptor binding	3/3388	31/18639	0.0967741935483871	0.532400883573904	0.938747747859454	1
GO:0072349	modified amino acid transmembrane transporter activity	3/3388	31/18639	0.0967741935483871	0.532400883573904	0.938747747859454	1
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	2/3388	23/18639	0.0869565217391304	0.478389199733073	0.939555593937096	1
GO:0005161	platelet-derived growth factor receptor binding	1/3388	14/18639	0.0714285714285714	0.392962556923596	0.939773351527483	1
GO:0008331	high voltage-gated calcium channel activity	1/3388	14/18639	0.0714285714285714	0.392962556923596	0.939773351527483	1
GO:0015386	potassium:proton antiporter activity	1/3388	14/18639	0.0714285714285714	0.392962556923596	0.939773351527483	1
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	1/3388	14/18639	0.0714285714285714	0.392962556923596	0.939773351527483	1
GO:0019992	diacylglycerol binding	1/3388	14/18639	0.0714285714285714	0.392962556923596	0.939773351527483	1
GO:0032454	histone H3K9 demethylase activity	1/3388	14/18639	0.0714285714285714	0.392962556923596	0.939773351527483	1
GO:0042813	Wnt receptor activity	1/3388	14/18639	0.0714285714285714	0.392962556923596	0.939773351527483	1
GO:0015101	organic cation transmembrane transporter activity	10/3388	81/18639	0.123456790123457	0.679194542830906	0.940292203313409	1
GO:0005125	cytokine activity	34/3388	234/18639	0.145299145299145	0.799359731177913	0.941655402570227	1
GO:0015085	calcium ion transmembrane transporter activity	20/3388	147/18639	0.136054421768707	0.748500108425897	0.943822327671124	1
GO:0003777	microtubule motor activity	8/3388	68/18639	0.117647058823529	0.647232446697687	0.943983253584774	1
GO:0101005	deubiquitinase activity	15/3388	115/18639	0.130434782608696	0.71758379959961	0.944858588095912	1
GO:0071813	lipoprotein particle binding	3/3388	32/18639	0.09375	0.51576335596222	0.947046660029538	1
GO:0071814	protein-lipid complex binding	3/3388	32/18639	0.09375	0.51576335596222	0.947046660029538	1
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	2/3388	24/18639	0.0833333333333333	0.458456316410862	0.948754990330015	1
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	2/3388	24/18639	0.0833333333333333	0.458456316410862	0.948754990330015	1
GO:0005315	phosphate transmembrane transporter activity	2/3388	24/18639	0.0833333333333333	0.458456316410862	0.948754990330015	1
GO:0015149	hexose transmembrane transporter activity	2/3388	24/18639	0.0833333333333333	0.458456316410862	0.948754990330015	1
GO:0030215	semaphorin receptor binding	2/3388	24/18639	0.0833333333333333	0.458456316410862	0.948754990330015	1
GO:0055056	D-glucose transmembrane transporter activity	2/3388	24/18639	0.0833333333333333	0.458456316410862	0.948754990330015	1
GO:0015179	L-amino acid transmembrane transporter activity	7/3388	62/18639	0.112903225806452	0.621134364169555	0.949630627888084	1
GO:0004467	long-chain fatty acid-CoA ligase activity	1/3388	15/18639	0.0666666666666667	0.366765053128689	0.950728942669759	1
GO:0010181	FMN binding	1/3388	15/18639	0.0666666666666667	0.366765053128689	0.950728942669759	1
GO:0015250	water channel activity	1/3388	15/18639	0.0666666666666667	0.366765053128689	0.950728942669759	1
GO:0015556	C4-dicarboxylate transmembrane transporter activity	1/3388	15/18639	0.0666666666666667	0.366765053128689	0.950728942669759	1
GO:0045504	dynein heavy chain binding	1/3388	15/18639	0.0666666666666667	0.366765053128689	0.950728942669759	1
GO:0051371	muscle alpha-actinin binding	1/3388	15/18639	0.0666666666666667	0.366765053128689	0.950728942669759	1
GO:0141050	histone H3K deacetylase activity	1/3388	15/18639	0.0666666666666667	0.366765053128689	0.950728942669759	1
GO:0141051	histone H4K deacetylase activity	1/3388	15/18639	0.0666666666666667	0.366765053128689	0.950728942669759	1
GO:0038187	pattern recognition receptor activity	5/3388	48/18639	0.104166666666667	0.573070395513577	0.952136199484861	1
GO:0072341	modified amino acid binding	11/3388	91/18639	0.120879120879121	0.665013557870701	0.956172924151493	1
GO:0001848	complement binding	2/3388	25/18639	0.08	0.440118063754427	0.956608270373052	1
GO:0005004	GPI-linked ephrin receptor activity	5/3388	49/18639	0.102040816326531	0.561375081319423	0.957790926976346	1
GO:0005008	hepatocyte growth factor receptor activity	5/3388	49/18639	0.102040816326531	0.561375081319423	0.957790926976346	1
GO:0005009	insulin receptor activity	5/3388	49/18639	0.102040816326531	0.561375081319423	0.957790926976346	1
GO:0005011	macrophage colony-stimulating factor receptor activity	5/3388	49/18639	0.102040816326531	0.561375081319423	0.957790926976346	1
GO:0005018	platelet-derived growth factor alpha-receptor activity	5/3388	49/18639	0.102040816326531	0.561375081319423	0.957790926976346	1
GO:0005020	stem cell factor receptor activity	5/3388	49/18639	0.102040816326531	0.561375081319423	0.957790926976346	1
GO:0008288	boss receptor activity	5/3388	49/18639	0.102040816326531	0.561375081319423	0.957790926976346	1
GO:0036332	placental growth factor receptor activity	5/3388	49/18639	0.102040816326531	0.561375081319423	0.957790926976346	1
GO:0038062	protein tyrosine kinase collagen receptor activity	5/3388	49/18639	0.102040816326531	0.561375081319423	0.957790926976346	1
GO:0060175	brain-derived neurotrophic factor receptor activity	5/3388	49/18639	0.102040816326531	0.561375081319423	0.957790926976346	1
GO:0015562	efflux transmembrane transporter activity	1/3388	16/18639	0.0625	0.343842237308146	0.959692126853331	1
GO:0022841	potassium ion leak channel activity	1/3388	16/18639	0.0625	0.343842237308146	0.959692126853331	1
GO:0055102	lipase inhibitor activity	1/3388	16/18639	0.0625	0.343842237308146	0.959692126853331	1
GO:0140328	floppase activity	1/3388	16/18639	0.0625	0.343842237308146	0.959692126853331	1
GO:0051427	hormone receptor binding	3/3388	34/18639	0.0882352941176471	0.485424335023266	0.960594928134598	1
GO:0090482	vitamin transmembrane transporter activity	3/3388	34/18639	0.0882352941176471	0.485424335023266	0.960594928134598	1
GO:0008013	beta-catenin binding	13/3388	106/18639	0.122641509433962	0.674709295849948	0.961864017627402	1
GO:0005006	epidermal growth factor receptor activity	5/3388	50/18639	0.1	0.550147579693034	0.962827781446716	1
GO:0005017	platelet-derived growth factor receptor activity	5/3388	50/18639	0.1	0.550147579693034	0.962827781446716	1
GO:0005019	platelet-derived growth factor beta-receptor activity	5/3388	50/18639	0.1	0.550147579693034	0.962827781446716	1
GO:0008066	glutamate receptor activity	2/3388	26/18639	0.0769230769230769	0.423190445917719	0.963300687622578	1
GO:0015145	monosaccharide transmembrane transporter activity	2/3388	26/18639	0.0769230769230769	0.423190445917719	0.963300687622578	1
GO:0008201	heparin binding	23/3388	172/18639	0.133720930232558	0.735662461217429	0.963328273175141	1
GO:0017171	serine hydrolase activity	27/3388	198/18639	0.136363636363636	0.750201245035956	0.964490781604382	1
GO:0004713	protein tyrosine kinase activity	18/3388	140/18639	0.128571428571429	0.707332602462473	0.964505855938488	1
GO:0005245	voltage-gated calcium channel activity	4/3388	43/18639	0.0930232558139535	0.511765190412125	0.966000612412721	1
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	1/3388	17/18639	0.0588235294117647	0.323616223348844	0.967025159888874	1
GO:0005132	type I interferon receptor binding	1/3388	17/18639	0.0588235294117647	0.323616223348844	0.967025159888874	1
GO:0019198	transmembrane receptor protein phosphatase activity	1/3388	17/18639	0.0588235294117647	0.323616223348844	0.967025159888874	1
GO:0046965	nuclear retinoid X receptor binding	1/3388	17/18639	0.0588235294117647	0.323616223348844	0.967025159888874	1
GO:0005010	insulin-like growth factor receptor activity	5/3388	51/18639	0.0980392156862745	0.539360372248073	0.967306260366954	1
GO:0005030	neurotrophin receptor activity	5/3388	51/18639	0.0980392156862745	0.539360372248073	0.967306260366954	1
GO:0004866	endopeptidase inhibitor activity	21/3388	161/18639	0.130434782608696	0.71758379959961	0.968293281103434	1
GO:0005044	scavenger receptor activity	2/3388	27/18639	0.0740740740740741	0.407516725698544	0.968994646412503	1
GO:0005104	fibroblast growth factor receptor binding	2/3388	27/18639	0.0740740740740741	0.407516725698544	0.968994646412503	1
GO:0036002	pre-mRNA binding	6/3388	59/18639	0.101694915254237	0.559472114942069	0.969267987500026	1
GO:0008236	serine-type peptidase activity	26/3388	194/18639	0.134020618556701	0.737311189279324	0.969996142135926	1
GO:0004867	serine-type endopeptidase inhibitor activity	11/3388	95/18639	0.115789473684211	0.637012987012987	0.970345666951874	1
GO:0015171	amino acid transmembrane transporter activity	12/3388	102/18639	0.117647058823529	0.647232446697687	0.970665713630309	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	3/3388	36/18639	0.0833333333333333	0.458456316410862	0.970832385697801	1
GO:0016500	protein-hormone receptor activity	7/3388	67/18639	0.104477611940299	0.574781053410633	0.971504958601651	1
GO:0030414	peptidase inhibitor activity	22/3388	169/18639	0.130177514792899	0.716168446937678	0.971770900163269	1
GO:0005372	water transmembrane transporter activity	1/3388	18/18639	0.0555555555555556	0.305637544273908	0.973024448810391	1
GO:0015280	ligand-gated sodium channel activity	1/3388	18/18639	0.0555555555555556	0.305637544273908	0.973024448810391	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/3388	18/18639	0.0555555555555556	0.305637544273908	0.973024448810391	1
GO:0022851	GABA-gated chloride ion channel activity	1/3388	18/18639	0.0555555555555556	0.305637544273908	0.973024448810391	1
GO:0051119	sugar transmembrane transporter activity	2/3388	28/18639	0.0714285714285714	0.392962556923596	0.973831885097338	1
GO:0005003	ephrin receptor activity	5/3388	53/18639	0.0943396226415094	0.519007150653806	0.974804070713616	1
GO:0005005	transmembrane-ephrin receptor activity	5/3388	53/18639	0.0943396226415094	0.519007150653806	0.974804070713616	1
GO:0015026	coreceptor activity	6/3388	61/18639	0.0983606557377049	0.541128766911181	0.975989978328189	1
GO:0030165	PDZ domain binding	9/3388	83/18639	0.108433734939759	0.596545568341844	0.976071963304442	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	4/3388	46/18639	0.0869565217391304	0.478389199733073	0.977650419890941	1
GO:0004890	GABA-A receptor activity	1/3388	19/18639	0.0526315789473684	0.289551357733176	0.977932518593453	1
GO:0008381	mechanosensitive monoatomic ion channel activity	1/3388	19/18639	0.0526315789473684	0.289551357733176	0.977932518593453	1
GO:0008574	plus-end-directed microtubule motor activity	1/3388	19/18639	0.0526315789473684	0.289551357733176	0.977932518593453	1
GO:0016918	retinal binding	1/3388	19/18639	0.0526315789473684	0.289551357733176	0.977932518593453	1
GO:0022821	solute:potassium antiporter activity	1/3388	19/18639	0.0526315789473684	0.289551357733176	0.977932518593453	1
GO:0034987	immunoglobulin receptor binding	1/3388	19/18639	0.0526315789473684	0.289551357733176	0.977932518593453	1
GO:0046624	sphingolipid transporter activity	1/3388	19/18639	0.0526315789473684	0.289551357733176	0.977932518593453	1
GO:0099589	serotonin receptor activity	1/3388	19/18639	0.0526315789473684	0.289551357733176	0.977932518593453	1
GO:1990380	K48-linked deubiquitinase activity	1/3388	19/18639	0.0526315789473684	0.289551357733176	0.977932518593453	1
GO:0005501	retinoid binding	3/3388	38/18639	0.0789473684210526	0.434327036599764	0.978514133930996	1
GO:0019840	isoprenoid binding	3/3388	38/18639	0.0789473684210526	0.434327036599764	0.978514133930996	1
GO:0008514	organic anion transmembrane transporter activity	37/3388	269/18639	0.137546468401487	0.756708566864025	0.97877519875545	1
GO:0099095	ligand-gated monoatomic anion channel activity	4/3388	47/18639	0.0851063829787234	0.468210706121731	0.980613283476592	1
GO:0005096	GTPase activator activity	37/3388	271/18639	0.136531365313653	0.751124001794918	0.981389239540476	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	2/3388	30/18639	0.0666666666666667	0.366765053128689	0.981412597164624	1
GO:0031624	ubiquitin conjugating enzyme binding	2/3388	30/18639	0.0666666666666667	0.366765053128689	0.981412597164624	1
GO:0048019	receptor antagonist activity	2/3388	30/18639	0.0666666666666667	0.366765053128689	0.981412597164624	1
GO:0001972	retinoic acid binding	1/3388	20/18639	0.05	0.275073789846517	0.981947804683968	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/3388	20/18639	0.05	0.275073789846517	0.981947804683968	1
GO:0071855	neuropeptide receptor binding	3/3388	40/18639	0.075	0.412610684769776	0.984242289213086	1
GO:0005452	solute:inorganic anion antiporter activity	2/3388	31/18639	0.0645161290322581	0.354933922382603	0.984355000564981	1
GO:0001846	opsonin binding	1/3388	21/18639	0.0476190476190476	0.261975037949064	0.985232666262501	1
GO:0005248	voltage-gated sodium channel activity	1/3388	21/18639	0.0476190476190476	0.261975037949064	0.985232666262501	1
GO:0061891	calcium ion sensor activity	1/3388	21/18639	0.0476190476190476	0.261975037949064	0.985232666262501	1
GO:0001530	lipopolysaccharide binding	3/3388	41/18639	0.0731707317073171	0.402547009531488	0.986525963399249	1
GO:0004812	aminoacyl-tRNA ligase activity	3/3388	41/18639	0.0731707317073171	0.402547009531488	0.986525963399249	1
GO:0015175	neutral L-amino acid transmembrane transporter activity	3/3388	41/18639	0.0731707317073171	0.402547009531488	0.986525963399249	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	3/3388	41/18639	0.0731707317073171	0.402547009531488	0.986525963399249	1
GO:0042910	xenobiotic transmembrane transporter activity	2/3388	32/18639	0.0625	0.343842237308146	0.986842223267343	1
GO:0050321	tau-protein kinase activity	1/3388	22/18639	0.0454545454545455	0.250067081678652	0.987919943451386	1
GO:0001786	phosphatidylserine binding	5/3388	59/18639	0.0847457627118644	0.466226762451724	0.988777454977606	1
GO:0015459	potassium channel regulator activity	5/3388	59/18639	0.0847457627118644	0.466226762451724	0.988777454977606	1
GO:0070888	E-box binding	5/3388	59/18639	0.0847457627118644	0.466226762451724	0.988777454977606	1
GO:0019956	chemokine binding	2/3388	33/18639	0.0606060606060606	0.333422775571536	0.988942467428118	1
GO:0016597	amino acid binding	4/3388	51/18639	0.0784313725490196	0.431488297798458	0.989141548274335	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/3388	23/18639	0.0434782608695652	0.239194599866537	0.990118322974762	1
GO:0005283	amino acid:sodium symporter activity	1/3388	23/18639	0.0434782608695652	0.239194599866537	0.990118322974762	1
GO:0016917	GABA receptor activity	1/3388	23/18639	0.0434782608695652	0.239194599866537	0.990118322974762	1
GO:0043274	phospholipase binding	1/3388	23/18639	0.0434782608695652	0.239194599866537	0.990118322974762	1
GO:0004497	monooxygenase activity	11/3388	106/18639	0.10377358490566	0.570907865719187	0.990632302344905	1
GO:0005540	hyaluronic acid binding	1/3388	24/18639	0.0416666666666667	0.229228158205431	0.991916728741925	1
GO:0050431	transforming growth factor beta binding	1/3388	24/18639	0.0416666666666667	0.229228158205431	0.991916728741925	1
GO:0005343	organic acid:sodium symporter activity	2/3388	35/18639	0.0571428571428571	0.314370045538877	0.992207384583373	1
GO:0005319	lipid transporter activity	21/3388	178/18639	0.117977528089888	0.649050515368186	0.99233969977988	1
GO:0004843	cysteine-type deubiquitinase activity	11/3388	108/18639	0.101851851851852	0.560335497835498	0.99248749855501	1
GO:0019199	transmembrane receptor protein kinase activity	7/3388	78/18639	0.0897435897435897	0.493722186904005	0.992607002400068	1
GO:0004715	non-membrane spanning protein tyrosine kinase activity	3/3388	45/18639	0.0666666666666667	0.366765053128689	0.992863357235133	1
GO:0140303	intramembrane lipid transporter activity	3/3388	45/18639	0.0666666666666667	0.366765053128689	0.992863357235133	1
GO:0015294	solute:monoatomic cation symporter activity	12/3388	116/18639	0.103448275862069	0.569118185889346	0.993051312487145	1
GO:0042379	chemokine receptor binding	6/3388	72/18639	0.0833333333333333	0.458456316410862	0.994270561382698	1
GO:0005253	monoatomic anion channel activity	10/3388	103/18639	0.0970873786407767	0.534123863779645	0.994283708790012	1
GO:0005539	glycosaminoglycan binding	30/3388	242/18639	0.12396694214876	0.682001131850869	0.994351183493439	1
GO:0030280	structural constituent of skin epidermis	2/3388	37/18639	0.0540540540540541	0.297377070104343	0.99452262058614	1
GO:0042805	actinin binding	2/3388	37/18639	0.0540540540540541	0.297377070104343	0.99452262058614	1
GO:0019865	immunoglobulin binding	1/3388	26/18639	0.0384615384615385	0.211595222958859	0.994591403582684	1
GO:0030247	polysaccharide binding	1/3388	26/18639	0.0384615384615385	0.211595222958859	0.994591403582684	1
GO:0043548	phosphatidylinositol 3-kinase binding	1/3388	26/18639	0.0384615384615385	0.211595222958859	0.994591403582684	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	4/3388	56/18639	0.0714285714285714	0.392962556923596	0.994851071939028	1
GO:0170055	lipid transmembrane transporter activity	4/3388	56/18639	0.0714285714285714	0.392962556923596	0.994851071939028	1
GO:0008395	steroid hydroxylase activity	1/3388	27/18639	0.037037037037037	0.203758362849272	0.995575894243075	1
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	1/3388	27/18639	0.037037037037037	0.203758362849272	0.995575894243075	1
GO:0051393	alpha-actinin binding	1/3388	28/18639	0.0357142857142857	0.196481278461798	0.99638122791514	1
GO:0015144	carbohydrate transmembrane transporter activity	2/3388	40/18639	0.05	0.275073789846517	0.99678631053277	1
GO:0005416	amino acid:monoatomic cation symporter activity	1/3388	29/18639	0.0344827586206897	0.189706061963115	0.997039999599816	1
GO:0008227	G protein-coupled amine receptor activity	2/3388	41/18639	0.0487804878048781	0.268364673020992	0.997312482180643	1
GO:0004252	serine-type endopeptidase activity	19/3388	176/18639	0.107954545454545	0.593909318986798	0.997497947069303	1
GO:0022839	monoatomic ion-gated channel activity	1/3388	30/18639	0.0333333333333333	0.183382526564345	0.997578875545857	1
GO:0015291	secondary active transmembrane transporter activity	35/3388	287/18639	0.121951219512195	0.670911682552481	0.997803863127561	1
GO:0008509	monoatomic anion transmembrane transporter activity	15/3388	149/18639	0.100671140939597	0.553839845328558	0.997919683991863	1
GO:0005184	neuropeptide hormone activity	1/3388	31/18639	0.032258064516129	0.177466961191301	0.998019671378553	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	1/3388	31/18639	0.032258064516129	0.177466961191301	0.998019671378553	1
GO:0017046	peptide hormone binding	3/3388	53/18639	0.0566037735849057	0.311404290392284	0.998071836029989	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	3/3388	53/18639	0.0566037735849057	0.311404290392284	0.998071836029989	1
GO:0022824	transmitter-gated monoatomic ion channel activity	4/3388	63/18639	0.0634920634920635	0.349300050598752	0.99824892171632	1
GO:0022835	transmitter-gated channel activity	4/3388	63/18639	0.0634920634920635	0.349300050598752	0.99824892171632	1
GO:0160041	neuropeptide activity	1/3388	32/18639	0.03125	0.171921118654073	0.99838023422085	1
GO:0019955	cytokine binding	14/3388	144/18639	0.0972222222222222	0.534865702479339	0.998399885316929	1
GO:0046943	carboxylic acid transmembrane transporter activity	20/3388	188/18639	0.106382978723404	0.585263382652164	0.998465385054511	1
GO:0005342	organic acid transmembrane transporter activity	20/3388	189/18639	0.105820105820106	0.58216675099792	0.998612231293427	1
GO:0005254	chloride channel activity	6/3388	83/18639	0.072289156626506	0.39769704556123	0.99876815899453	1
GO:0019825	oxygen binding	1/3388	34/18639	0.0294117647058824	0.161808111674422	0.998916406124006	1
GO:0008188	neuropeptide receptor activity	2/3388	48/18639	0.0416666666666667	0.229228158205431	0.999241026253502	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/3388	36/18639	0.0277777777777778	0.152818772136954	0.999275130082051	1
GO:0098960	postsynaptic neurotransmitter receptor activity	4/3388	69/18639	0.0579710144927536	0.318926133155382	0.999323342866624	1
GO:0015108	chloride transmembrane transporter activity	10/3388	121/18639	0.0826446280991736	0.454667421233913	0.999373974846334	1
GO:0015370	solute:sodium symporter activity	5/3388	79/18639	0.0632911392405063	0.348194670691794	0.999396760672055	1
GO:0030594	neurotransmitter receptor activity	7/3388	97/18639	0.0721649484536082	0.397013717304251	0.999433961078369	1
GO:0001664	G protein-coupled receptor binding	34/3388	297/18639	0.114478114478114	0.629798576079568	0.999469782847028	1
GO:0048020	CCR chemokine receptor binding	2/3388	50/18639	0.04	0.220059031877214	0.999473051676427	1
GO:0015293	symporter activity	13/3388	146/18639	0.089041095890411	0.48985743397325	0.999474989277213	1
GO:0001216	DNA-binding transcription activator activity	63/3388	491/18639	0.128309572301426	0.705892006530777	0.999515422661773	1
GO:0005272	sodium channel activity	2/3388	51/18639	0.0392156862745098	0.215744148899229	0.999561157415883	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	4/3388	73/18639	0.0547945205479452	0.301450728598923	0.999645132869483	1
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	61/3388	484/18639	0.12603305785124	0.693367817381717	0.999687373278612	1
GO:0005179	hormone activity	10/3388	132/18639	0.0757575757575758	0.41677846946442	0.999853028723809	1
GO:0015103	inorganic anion transmembrane transporter activity	14/3388	165/18639	0.0848484848484849	0.46679188580015	0.999865882832383	1
GO:0046873	metal ion transmembrane transporter activity	53/3388	450/18639	0.117777777777778	0.647951593860685	0.999930465896364	1
GO:0005261	monoatomic cation channel activity	37/3388	341/18639	0.108504398826979	0.596934324007105	0.999936305764465	1
GO:0015081	sodium ion transmembrane transporter activity	13/3388	164/18639	0.0792682926829268	0.436092593659113	0.999944559708349	1
GO:0015079	potassium ion transmembrane transporter activity	12/3388	160/18639	0.075	0.412610684769776	0.999968111588923	1
GO:0005249	voltage-gated potassium channel activity	5/3388	98/18639	0.0510204081632653	0.280687540659711	0.999970003010466	1
GO:0005244	voltage-gated monoatomic ion channel activity	13/3388	173/18639	0.0751445086705202	0.413405695723089	0.99998296314462	1
GO:0003823	antigen binding	13/3388	174/18639	0.0747126436781609	0.411029800920083	0.999985087360986	1
GO:0022832	voltage-gated channel activity	13/3388	175/18639	0.0742857142857143	0.40868105920054	0.99998695190617	1
GO:0005267	potassium channel activity	7/3388	124/18639	0.0564516129032258	0.310567182084777	0.999989749445586	1
GO:0022843	voltage-gated monoatomic cation channel activity	9/3388	143/18639	0.0629370629370629	0.346246728478133	0.999990746071956	1
GO:0099094	ligand-gated monoatomic cation channel activity	8/3388	136/18639	0.0588235294117647	0.323616223348844	0.999993214536443	1
GO:0005216	monoatomic ion channel activity	48/3388	448/18639	0.107142857142857	0.589443835385394	0.999996128637554	1
GO:0015276	ligand-gated monoatomic ion channel activity	13/3388	186/18639	0.0698924731182796	0.38451174924782	0.999997071929681	1
GO:0022834	ligand-gated channel activity	13/3388	188/18639	0.0691489361702128	0.380421198723907	0.999997779021713	1
GO:0001653	peptide receptor activity	6/3388	128/18639	0.046875	0.25788167798111	0.999998850331441	1
GO:0003730	mRNA 3'-UTR binding	21/3388	262/18639	0.0801526717557252	0.440957983723424	0.999999213691626	1
GO:0008528	G protein-coupled peptide receptor activity	5/3388	122/18639	0.040983606557377	0.225470319546325	0.99999944645042	1
GO:0004896	cytokine receptor activity	2/3388	96/18639	0.0208333333333333	0.114614079102715	0.99999990800054	1
GO:0030527	structural constituent of chromatin	2/3388	98/18639	0.0204081632653061	0.112275016263885	0.999999937317432	1
GO:0022836	gated channel activity	24/3388	318/18639	0.0754716981132075	0.415205720523045	0.999999986162345	1
GO:0140375	immune receptor activity	2/3388	156/18639	0.0128205128205128	0.0705317409862864	0.999999999999202	1
GO:0030371	translation repressor activity	7/3388	329/18639	0.0212765957446809	0.117052676530433	1	1
GO:0045182	translation regulator activity	14/3388	356/18639	0.0393258426966292	0.216350171789395	1	1