ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 122/3947 175/18639 0.697142857142857 3.29213217995584 1.76828406765377e-43 2.39779319573852e-40 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 56/3947 68/18639 0.823529411764706 3.8889700293596 5.95899990642297e-27 4.04020193655477e-24 GO:0009055 electron transfer activity 74/3947 116/18639 0.637931034482759 3.01251496116649 3.43414585622742e-23 1.55223392701479e-20 GO:0022853 active monoatomic ion transmembrane transporter activity 73/3947 118/18639 0.61864406779661 2.92143571818115 9.89326843516158e-22 3.35381799951977e-19 GO:0008137 NADH dehydrogenase (ubiquinone) activity 37/3947 41/18639 0.902439024390244 4.26160653043065 4.03685221221384e-21 1.09479431995239e-18 GO:0015078 proton transmembrane transporter activity 96/3947 185/18639 0.518918918918919 2.45050157834551 2.39985012737277e-20 5.42366128786246e-18 GO:0003954 NADH dehydrogenase activity 38/3947 44/18639 0.863636363636364 4.07836792039984 3.73952755929923e-20 7.24399910058537e-18 GO:0015399 primary active transmembrane transporter activity 82/3947 166/18639 0.493975903614458 2.33271265960727 6.00343840658927e-16 1.01758280991688e-13 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 41/3947 58/18639 0.706896551724138 3.33819225426557 7.78916564664138e-16 1.17356762409397e-13 GO:0019843 rRNA binding 40/3947 65/18639 0.615384615384615 2.90604353842256 1.96694054053184e-12 2.66717137296118e-10 GO:0016651 oxidoreductase activity, acting on NAD(P)H 48/3947 88/18639 0.545454545454545 2.57581131814727 6.54905649241815e-12 8.07320054883547e-10 GO:0030695 GTPase regulator activity 156/3947 489/18639 0.319018404907975 1.50650723310863 1.37230463688343e-08 1.55070423967828e-06 GO:0060589 nucleoside-triphosphatase regulator activity 156/3947 490/18639 0.318367346938775 1.50343272855126 1.59871269509206e-08 1.66758031888064e-06 GO:0031625 ubiquitin protein ligase binding 100/3947 302/18639 0.33112582781457 1.5636823675287 8.16867105441273e-07 7.91194139270262e-05 GO:0055105 ubiquitin-protein transferase inhibitor activity 12/3947 15/18639 0.8 3.77785659994933 1.90652499945282e-06 0.000172349859950535 GO:0043021 ribonucleoprotein complex binding 64/3947 177/18639 0.361581920903955 1.7075058078867 3.05756482848226e-06 0.000259128619213872 GO:0044389 ubiquitin-like protein ligase binding 103/3947 322/18639 0.319875776397516 1.51055601628409 3.33996826749762e-06 0.000266411586513339 GO:0005085 guanyl-nucleotide exchange factor activity 78/3947 230/18639 0.339130434782609 1.60148268910895 4.70265402057257e-06 0.000349017515831085 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 13/3947 18/18639 0.722222222222222 3.41056498606537 4.89036342241196e-06 0.000349017515831085 GO:0005096 GTPase activator activity 88/3947 271/18639 0.324723247232472 1.53344732839272 8.71080831448194e-06 0.000590592803721876 GO:0004129 cytochrome-c oxidase activity 11/3947 15/18639 0.733333333333333 3.46303521662022 2.19636315153873e-05 0.00141822306356501 GO:1990948 ubiquitin ligase inhibitor activity 9/3947 11/18639 0.818181818181818 3.8637169772209 3.06751367001621e-05 0.00189070388024635 GO:0004706 JUN kinase kinase kinase activity 12/3947 18/18639 0.666666666666667 3.14821383329111 4.07502663169375e-05 0.00240249396198988 GO:0016675 oxidoreductase activity, acting on a heme group of donors 11/3947 16/18639 0.6875 3.24659551558145 5.67637451920037e-05 0.00320715160334821 GO:0140142 nucleocytoplasmic carrier activity 17/3947 32/18639 0.53125 2.50873289840385 6.93749842021781e-05 0.00376289914312614 GO:0051536 iron-sulfur cluster binding 31/3947 76/18639 0.407894736842105 1.92620977957943 8.25679864805844e-05 0.00430623806414125 GO:0015252 proton channel activity 15/3947 27/18639 0.555555555555556 2.62351152774259 9.47003503107889e-05 0.00474582395972198 GO:0005049 nuclear export signal receptor activity 9/3947 12/18639 0.75 3.5417405624525 9.94682573799651e-05 0.00474582395972198 GO:0140297 DNA-binding transcription factor binding 138/3947 488/18639 0.282786885245902 1.33541037600668 0.000101496235126798 0.00474582395972198 GO:0051540 metal cluster binding 31/3947 77/18639 0.402597402597403 1.90119406815632 0.000110429517452886 0.00499141418887044 GO:0043022 ribosome binding 41/3947 112/18639 0.366071428571429 1.72870670310181 0.000124748513597856 0.0054567414335062 GO:0004709 MAP kinase kinase kinase activity 14/3947 25/18639 0.56 2.64449961996453 0.00014488191879759 0.00613937130904786 GO:0051537 2 iron, 2 sulfur cluster binding 15/3947 28/18639 0.535714285714286 2.52981468746607 0.000164116093697007 0.00674367948645885 GO:0051020 GTPase binding 93/3947 315/18639 0.295238095238095 1.39420898331463 0.000270636804248392 0.0107936325459065 GO:0070990 snRNP binding 8/3947 11/18639 0.727272727272727 3.43441509086303 0.000356005995299647 0.0137926894178949 GO:0019838 growth factor binding 46/3947 136/18639 0.338235294117647 1.59725554777269 0.000415527853335342 0.0156515491422979 GO:0031267 small GTPase binding 84/3947 283/18639 0.296819787985866 1.40167824379745 0.000432441218129096 0.0158483862644069 GO:0016530 metallochaperone activity 9/3947 14/18639 0.642857142857143 3.03577762495928 0.000595897625036389 0.0212641363039301 GO:0003712 transcription coregulator activity 135/3947 495/18639 0.272727272727273 1.28790565907363 0.000638782320249119 0.0222099699040463 GO:0003697 single-stranded DNA binding 41/3947 121/18639 0.338842975206612 1.60012521278846 0.000797466447249944 0.0270341125617731 GO:0019205 nucleobase-containing compound kinase activity 19/3947 44/18639 0.431818181818182 2.03918396019992 0.000830976230807361 0.0274830187554825 GO:0031386 protein tag activity 9/3947 15/18639 0.6 2.833392449962 0.00120986542363134 0.0381529654521884 GO:0141047 molecular tag activity 9/3947 15/18639 0.6 2.833392449962 0.00120986542363134 0.0381529654521884 GO:0016776 phosphotransferase activity, phosphate group as acceptor 17/3947 39/18639 0.435897435897436 2.05844750638265 0.00135793004802835 0.04184893511651 GO:0055106 ubiquitin-protein transferase regulator activity 16/3947 36/18639 0.444444444444444 2.09880922219407 0.00145430846746299 0.0438231618195513 GO:0000287 magnesium ion binding 68/3947 230/18639 0.295652173913043 1.39616439563345 0.00160713161082478 0.0455771533785662 GO:0042625 ATPase-coupled ion transmembrane transporter activity 12/3947 24/18639 0.5 2.36116037496833 0.00164696203211633 0.0455771533785662 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 12/3947 24/18639 0.5 2.36116037496833 0.00164696203211633 0.0455771533785662 GO:0046961 proton-transporting ATPase activity, rotational mechanism 12/3947 24/18639 0.5 2.36116037496833 0.00164696203211633 0.0455771533785662 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 25/3947 67/18639 0.373134328358209 1.76205998131965 0.0018019769958541 0.0479832558913252 GO:0022804 active transmembrane transporter activity 123/3947 457/18639 0.269146608315098 1.27099661322146 0.0018150609551751 0.0479832558913252 GO:0035325 Toll-like receptor binding 8/3947 13/18639 0.615384615384615 2.90604353842256 0.00184006586013932 0.0479832558913252 GO:0016407 acetyltransferase activity 33/3947 96/18639 0.34375 1.62329775779073 0.00188436086073967 0.0482111948521321 GO:0016504 peptidase activator activity 22/3947 57/18639 0.385964912280702 1.82265011401064 0.00201351111315949 0.0505615012860049 GO:0005178 integrin binding 50/3947 161/18639 0.31055900621118 1.46655923911076 0.00207035505664868 0.051043662851193 GO:0003743 translation initiation factor activity 20/3947 51/18639 0.392156862745098 1.85189049017124 0.00253836858114743 0.0590495223198516 GO:0034062 5'-3' RNA polymerase activity 11/3947 22/18639 0.5 2.36116037496833 0.0025692638767487 0.0590495223198516 GO:0061133 endopeptidase activator activity 11/3947 22/18639 0.5 2.36116037496833 0.0025692638767487 0.0590495223198516 GO:0097747 RNA polymerase activity 11/3947 22/18639 0.5 2.36116037496833 0.0025692638767487 0.0590495223198516 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 96/3947 349/18639 0.275071633237822 1.29897648135794 0.00271663963704684 0.0613960557972586 GO:0030983 mismatched DNA binding 8/3947 14/18639 0.571428571428571 2.69846899996381 0.00349895684027654 0.0777800897609014 GO:0032977 membrane insertase activity 9/3947 17/18639 0.529411764705882 2.50005216173117 0.00388347278717269 0.0836948721949286 GO:0003684 damaged DNA binding 26/3947 74/18639 0.351351351351351 1.65919377700477 0.0038884785754281 0.0836948721949286 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 10/3947 20/18639 0.5 2.36116037496833 0.0040215864152736 0.0852073621736093 GO:0003713 transcription coactivator activity 72/3947 256/18639 0.28125 1.32815271091969 0.00482737838273978 0.100706539799925 GO:0046332 SMAD binding 27/3947 79/18639 0.341772151898734 1.6139577246619 0.00508783334016527 0.10394233726359 GO:0019955 cytokine binding 44/3947 144/18639 0.305555555555556 1.44293134025842 0.00513579395033963 0.10394233726359 GO:0140104 molecular carrier activity 70/3947 249/18639 0.281124497991968 1.327560050183 0.00545442366644924 0.108767624878017 GO:0019207 kinase regulator activity 79/3947 287/18639 0.275261324041812 1.29987226217769 0.00596563125440443 0.117237622912644 GO:0005041 low-density lipoprotein particle receptor activity 8/3947 15/18639 0.533333333333333 2.51857106663289 0.00611506131644249 0.118457473501372 GO:0030228 lipoprotein particle receptor activity 9/3947 18/18639 0.5 2.36116037496833 0.00632043133790386 0.120711336537995 GO:0042169 SH2 domain binding 16/3947 41/18639 0.390243902439024 1.84285687802406 0.00698114472062339 0.131208701831018 GO:0038187 pattern recognition receptor activity 18/3947 48/18639 0.375 1.77087028122625 0.00706359530506217 0.131208701831018 GO:0005080 protein kinase C binding 19/3947 52/18639 0.365384615384615 1.7254633509384 0.00788769574014647 0.144536694914035 GO:0051539 4 iron, 4 sulfur cluster binding 17/3947 45/18639 0.377777777777778 1.78398783886496 0.0080206370795338 0.145013118397971 GO:0033204 ribonuclease P RNA binding 6/3947 10/18639 0.6 2.833392449962 0.00853502989804152 0.148052898573429 GO:0047429 nucleoside triphosphate diphosphatase activity 6/3947 10/18639 0.6 2.833392449962 0.00853502989804152 0.148052898573429 GO:0097177 mitochondrial ribosome binding 6/3947 10/18639 0.6 2.833392449962 0.00853502989804152 0.148052898573429 GO:0044325 transmembrane transporter binding 41/3947 136/18639 0.301470588235294 1.42364081431914 0.00862550072809802 0.148052898573429 GO:0048487 beta-tubulin binding 16/3947 42/18639 0.380952380952381 1.7989793333092 0.00910039135041905 0.154251633389603 GO:0005035 death receptor activity 7/3947 13/18639 0.538461538461538 2.54278809611974 0.00968232560532615 0.159857320663557 GO:0008301 DNA binding, bending 9/3947 19/18639 0.473684210526316 2.23688877628579 0.00977928705567918 0.159857320663557 GO:0030515 snoRNA binding 13/3947 32/18639 0.40625 1.91844280466177 0.00987266142771116 0.159857320663557 GO:0034212 protein N-acetyltransferase activity 19/3947 53/18639 0.358490566037736 1.69290743865654 0.00990266588181328 0.159857320663557 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 15/3947 39/18639 0.384615384615385 1.8162772115141 0.0103149703610063 0.164554115406171 GO:0008135 translation factor activity, RNA binding 27/3947 83/18639 0.325301204819277 1.53617662949747 0.0105463707516556 0.165201478517569 GO:0030145 manganese ion binding 23/3947 68/18639 0.338235294117647 1.59725554777269 0.010619963848293 0.165201478517569 GO:0005525 GTP binding 99/3947 378/18639 0.261904761904762 1.23679829165008 0.010721039903795 0.165201478517569 GO:0016741 transferase activity, transferring one-carbon groups 60/3947 215/18639 0.27906976744186 1.3178569534707 0.0111636263704418 0.168216341981028 GO:0019001 guanyl nucleotide binding 104/3947 400/18639 0.26 1.22780339498353 0.0112888548084613 0.168216341981028 GO:0032561 guanyl ribonucleotide binding 104/3947 400/18639 0.26 1.22780339498353 0.0112888548084613 0.168216341981028 GO:0008198 ferrous iron binding 11/3947 26/18639 0.423076923076923 1.99790493266551 0.0121782959278762 0.170883049343727 GO:0038024 cargo receptor activity 22/3947 65/18639 0.338461538461538 1.59832394613241 0.0121866118317359 0.170883049343727 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 19/3947 54/18639 0.351851851851852 1.66155730090364 0.0123090515082252 0.170883049343727 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 19/3947 54/18639 0.351851851851852 1.66155730090364 0.0123090515082252 0.170883049343727 GO:0051287 NAD binding 19/3947 54/18639 0.351851851851852 1.66155730090364 0.0123090515082252 0.170883049343727 GO:0017124 SH3 domain binding 35/3947 115/18639 0.304347826086957 1.43722805432855 0.0123825617859639 0.170883049343727 GO:0004860 protein kinase inhibitor activity 27/3947 84/18639 0.321428571428571 1.51788881247964 0.0124759748414668 0.170883049343727 GO:0180051 translation factor activity 27/3947 84/18639 0.321428571428571 1.51788881247964 0.0124759748414668 0.170883049343727 GO:0008168 methyltransferase activity 57/3947 204/18639 0.279411764705882 1.31947197424701 0.0127824380745471 0.173329860290858 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 15/3947 40/18639 0.375 1.77087028122625 0.0133377277872961 0.177720004633992 GO:0005158 insulin receptor binding 10/3947 23/18639 0.434782608695652 2.05318293475507 0.0133683189326454 0.177720004633992 GO:0016830 carbon-carbon lyase activity 18/3947 51/18639 0.352941176470588 1.66670144115412 0.0141203273590134 0.185894795134196 GO:0016004 phospholipase activator activity 9/3947 20/18639 0.45 2.1250443374715 0.0144901330341928 0.188929042253514 GO:0004550 nucleoside diphosphate kinase activity 8/3947 17/18639 0.470588235294118 2.22226858820549 0.0154044278853488 0.192065874832697 GO:0015278 intracellularly gated calcium channel activity 8/3947 17/18639 0.470588235294118 2.22226858820549 0.0154044278853488 0.192065874832697 GO:0019864 IgG binding 6/3947 11/18639 0.545454545454545 2.57581131814727 0.0154389235669351 0.192065874832697 GO:0050786 RAGE receptor binding 6/3947 11/18639 0.545454545454545 2.57581131814727 0.0154389235669351 0.192065874832697 GO:0140031 phosphorylation-dependent protein binding 6/3947 11/18639 0.545454545454545 2.57581131814727 0.0154389235669351 0.192065874832697 GO:0071933 Arp2/3 complex binding 7/3947 14/18639 0.5 2.36116037496833 0.0158656943703757 0.195580741511177 GO:0005044 scavenger receptor activity 11/3947 27/18639 0.407407407407407 1.9239084536779 0.0166930678982128 0.203926126756545 GO:0019210 kinase inhibitor activity 28/3947 90/18639 0.311111111111111 1.46916645553585 0.0174976188746348 0.211846171375043 GO:0035035 histone acetyltransferase binding 10/3947 24/18639 0.416666666666667 1.96763364580694 0.018649997879197 0.219907801079923 GO:0048027 mRNA 5'-UTR binding 10/3947 24/18639 0.416666666666667 1.96763364580694 0.018649997879197 0.219907801079923 GO:0060229 lipase activator activity 10/3947 24/18639 0.416666666666667 1.96763364580694 0.018649997879197 0.219907801079923 GO:0003714 transcription corepressor activity 56/3947 204/18639 0.274509803921569 1.29632334311987 0.0191965950212864 0.223767552312749 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 47/3947 167/18639 0.281437125748503 1.32903637872469 0.019450684766007 0.223767552312749 GO:0016829 lyase activity 55/3947 200/18639 0.275 1.29863820623258 0.019472397620136 0.223767552312749 GO:0001540 amyloid-beta binding 26/3947 83/18639 0.313253012048193 1.47928119877534 0.0196781569007342 0.224231771070551 GO:0019887 protein kinase regulator activity 68/3947 255/18639 0.266666666666667 1.25928553331644 0.0206105962020778 0.229602974593834 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 9/3947 21/18639 0.428571428571429 2.02385174997285 0.0206809354233795 0.229602974593834 GO:0072542 protein phosphatase activator activity 9/3947 21/18639 0.428571428571429 2.02385174997285 0.0206809354233795 0.229602974593834 GO:0016853 isomerase activity 50/3947 180/18639 0.277777777777778 1.31175576387129 0.0208268184919185 0.229602974593834 GO:0016860 intramolecular oxidoreductase activity 18/3947 53/18639 0.339622641509434 1.6038070471483 0.0212859907106484 0.232772608093865 GO:0046875 ephrin receptor binding 11/3947 28/18639 0.392857142857143 1.85519743747512 0.0223471918119111 0.240177528650011 GO:0097718 disordered domain specific binding 11/3947 28/18639 0.392857142857143 1.85519743747512 0.0223471918119111 0.240177528650011 GO:0016854 racemase and epimerase activity 8/3947 18/18639 0.444444444444444 2.09880922219407 0.0226716251233049 0.240177528650011 GO:0070064 proline-rich region binding 8/3947 18/18639 0.444444444444444 2.09880922219407 0.0226716251233049 0.240177528650011 GO:0004197 cysteine-type endopeptidase activity 27/3947 88/18639 0.306818181818182 1.44889386645784 0.0232012871411102 0.242983236188406 GO:0016779 nucleotidyltransferase activity 39/3947 136/18639 0.286764705882353 1.35419492093772 0.0232948530269121 0.242983236188406 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 7/3947 15/18639 0.466666666666667 2.20374968330378 0.0243974982925673 0.24505931618312 GO:0050700 CARD domain binding 7/3947 15/18639 0.466666666666667 2.20374968330378 0.0243974982925673 0.24505931618312 GO:0061578 K63-linked deubiquitinase activity 7/3947 15/18639 0.466666666666667 2.20374968330378 0.0243974982925673 0.24505931618312 GO:0141050 histone H3K deacetylase activity 7/3947 15/18639 0.466666666666667 2.20374968330378 0.0243974982925673 0.24505931618312 GO:0141051 histone H4K deacetylase activity 7/3947 15/18639 0.466666666666667 2.20374968330378 0.0243974982925673 0.24505931618312 GO:0008080 N-acetyltransferase activity 22/3947 69/18639 0.318840579710145 1.50566748548705 0.0247938349370362 0.247209118931037 GO:0004300 enoyl-CoA hydratase activity 6/3947 12/18639 0.5 2.36116037496833 0.0254182767759524 0.247965347540946 GO:0004526 ribonuclease P activity 6/3947 12/18639 0.5 2.36116037496833 0.0254182767759524 0.247965347540946 GO:0035497 cAMP response element binding 6/3947 12/18639 0.5 2.36116037496833 0.0254182767759524 0.247965347540946 GO:0017069 snRNA binding 18/3947 54/18639 0.333333333333333 1.57410691664555 0.0257744603118598 0.249644058449157 GO:0019787 ubiquitin-like protein transferase activity 119/3947 479/18639 0.248434237995825 1.17318615708239 0.0282066159079528 0.270115514525852 GO:0001784 phosphotyrosine residue binding 16/3947 47/18639 0.340425531914894 1.60759855316993 0.028286432937073 0.270115514525852 GO:0008093 cytoskeletal anchor activity 9/3947 22/18639 0.409090909090909 1.93185848861045 0.0285661935298374 0.270879429555661 GO:0003785 actin monomer binding 11/3947 29/18639 0.379310344827586 1.79122511204494 0.0292823959508572 0.275742561870572 GO:0031593 polyubiquitin modification-dependent protein binding 19/3947 59/18639 0.322033898305085 1.52074736014909 0.0319529670266915 0.296768652658861 GO:0045309 protein phosphorylated amino acid binding 19/3947 59/18639 0.322033898305085 1.52074736014909 0.0319529670266915 0.296768652658861 GO:0005201 extracellular matrix structural constituent 46/3947 168/18639 0.273809523809524 1.29301639581599 0.0326450227717385 0.300410321256724 GO:0005507 copper ion binding 20/3947 63/18639 0.317460317460317 1.49914944442434 0.0327881471578135 0.300410321256724 GO:0042826 histone deacetylase binding 36/3947 127/18639 0.283464566929134 1.33861060628126 0.0335026356992653 0.301039499224723 GO:0052742 phosphatidylinositol kinase activity 10/3947 26/18639 0.384615384615385 1.8162772115141 0.0335228350906587 0.301039499224723 GO:0070006 metalloaminopeptidase activity 10/3947 26/18639 0.384615384615385 1.8162772115141 0.0335228350906587 0.301039499224723 GO:0019213 deacetylase activity 13/3947 37/18639 0.351351351351351 1.65919377700477 0.0354415873304916 0.309523765513988 GO:0005521 lamin binding 7/3947 16/18639 0.4375 2.06601532809729 0.0356089287759455 0.309523765513988 GO:0015923 mannosidase activity 7/3947 16/18639 0.4375 2.06601532809729 0.0356089287759455 0.309523765513988 GO:0043023 ribosomal large subunit binding 7/3947 16/18639 0.4375 2.06601532809729 0.0356089287759455 0.309523765513988 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 7/3947 16/18639 0.4375 2.06601532809729 0.0356089287759455 0.309523765513988 GO:0035091 phosphatidylinositol binding 73/3947 284/18639 0.257042253521127 1.2138359674133 0.0374310742413512 0.315054320153492 GO:0043995 histone H4K5 acetyltransferase activity 11/3947 30/18639 0.366666666666667 1.73151760831011 0.0376289226640334 0.315054320153492 GO:0043996 histone H4K8 acetyltransferase activity 11/3947 30/18639 0.366666666666667 1.73151760831011 0.0376289226640334 0.315054320153492 GO:0043997 histone H4K12 acetyltransferase activity 11/3947 30/18639 0.366666666666667 1.73151760831011 0.0376289226640334 0.315054320153492 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 14/3947 41/18639 0.341463414634146 1.61249976827105 0.0377708253874933 0.315054320153492 GO:0017080 sodium channel regulator activity 14/3947 41/18639 0.341463414634146 1.61249976827105 0.0377708253874933 0.315054320153492 GO:0042171 lysophosphatidic acid acyltransferase activity 9/3947 23/18639 0.391304347826087 1.84786464127956 0.0383362557708895 0.315054320153492 GO:0071617 lysophospholipid acyltransferase activity 9/3947 23/18639 0.391304347826087 1.84786464127956 0.0383362557708895 0.315054320153492 GO:0140102 catalytic activity, acting on a rRNA 9/3947 23/18639 0.391304347826087 1.84786464127956 0.0383362557708895 0.315054320153492 GO:0035673 oligopeptide transmembrane transporter activity 6/3947 13/18639 0.461538461538462 2.17953265381692 0.0389062349222035 0.317812376834385 GO:0004715 non-membrane spanning protein tyrosine kinase activity 15/3947 45/18639 0.333333333333333 1.57410691664555 0.039688618259929 0.318941034151712 GO:0016831 carboxy-lyase activity 12/3947 34/18639 0.352941176470588 1.66670144115412 0.0409985575773508 0.318941034151712 GO:0005031 tumor necrosis factor receptor activity 5/3947 10/18639 0.5 2.36116037496833 0.0411612691567475 0.318941034151712 GO:0008239 dipeptidyl-peptidase activity 5/3947 10/18639 0.5 2.36116037496833 0.0411612691567475 0.318941034151712 GO:0016303 1-phosphatidylinositol-3-kinase activity 5/3947 10/18639 0.5 2.36116037496833 0.0411612691567475 0.318941034151712 GO:0031720 haptoglobin binding 5/3947 10/18639 0.5 2.36116037496833 0.0411612691567475 0.318941034151712 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 5/3947 10/18639 0.5 2.36116037496833 0.0411612691567475 0.318941034151712 GO:0043422 protein kinase B binding 5/3947 10/18639 0.5 2.36116037496833 0.0411612691567475 0.318941034151712 GO:0070513 death domain binding 5/3947 10/18639 0.5 2.36116037496833 0.0411612691567475 0.318941034151712 GO:0000339 RNA cap binding 8/3947 20/18639 0.4 1.88892829997466 0.0437530296283196 0.331447531709505 GO:0016505 peptidase activator activity involved in apoptotic process 8/3947 20/18639 0.4 1.88892829997466 0.0437530296283196 0.331447531709505 GO:0043024 ribosomal small subunit binding 8/3947 20/18639 0.4 1.88892829997466 0.0437530296283196 0.331447531709505 GO:0061608 nuclear import signal receptor activity 8/3947 20/18639 0.4 1.88892829997466 0.0437530296283196 0.331447531709505 GO:0016755 aminoacyltransferase activity 121/3947 496/18639 0.243951612903226 1.15201776359342 0.0441376167540828 0.332503379547424 GO:0051219 phosphoprotein binding 27/3947 93/18639 0.290322580645161 1.3709963467558 0.0453569121139045 0.33943396949482 GO:0043539 protein serine/threonine kinase activator activity 22/3947 73/18639 0.301369863013699 1.42316515751516 0.0455582466431101 0.33943396949482 GO:0004402 histone acetyltransferase activity 14/3947 42/18639 0.333333333333333 1.57410691664555 0.0459580233739267 0.340541419098604 GO:0003924 GTPase activity 83/3947 331/18639 0.250755287009063 1.18414689499922 0.0481225575538372 0.35464232632067 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 7/3947 17/18639 0.411764705882353 1.9444850146798 0.0497520793993631 0.356024619089042 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 7/3947 17/18639 0.411764705882353 1.9444850146798 0.0497520793993631 0.356024619089042 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 7/3947 17/18639 0.411764705882353 1.9444850146798 0.0497520793993631 0.356024619089042 GO:0030169 low-density lipoprotein particle binding 7/3947 17/18639 0.411764705882353 1.9444850146798 0.0497520793993631 0.356024619089042 GO:0070403 NAD+ binding 7/3947 17/18639 0.411764705882353 1.9444850146798 0.0497520793993631 0.356024619089042 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 9/3947 24/18639 0.375 1.77087028122625 0.0501480105059049 0.356024619089042 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 9/3947 24/18639 0.375 1.77087028122625 0.0501480105059049 0.356024619089042 GO:0010485 histone H4 acetyltransferase activity 12/3947 35/18639 0.342857142857143 1.61908139997828 0.0507464438519189 0.356809100704904 GO:0008170 N-methyltransferase activity 28/3947 98/18639 0.285714285714286 1.3492344999819 0.0507847761327776 0.356809100704904 GO:0061659 ubiquitin-like protein ligase activity 92/3947 372/18639 0.247311827956989 1.16788577686606 0.0533340501337371 0.372788515367771 GO:0019789 SUMO transferase activity 10/3947 28/18639 0.357142857142857 1.68654312497738 0.0551313127745538 0.381418674093342 GO:0036408 histone H3K14 acetyltransferase activity 10/3947 28/18639 0.357142857142857 1.68654312497738 0.0551313127745538 0.381418674093342 GO:0005344 oxygen carrier activity 6/3947 14/18639 0.428571428571429 2.02385174997285 0.0561866403360744 0.382859720078979 GO:0019763 immunoglobulin receptor activity 6/3947 14/18639 0.428571428571429 2.02385174997285 0.0561866403360744 0.382859720078979 GO:0061665 SUMO ligase activity 6/3947 14/18639 0.428571428571429 2.02385174997285 0.0561866403360744 0.382859720078979 GO:0061733 protein-lysine-acetyltransferase activity 15/3947 47/18639 0.319148936170213 1.50712364359681 0.05684252897152 0.385392346426906 GO:0033218 amide binding 63/3947 247/18639 0.255060728744939 1.20447857184619 0.0572747404365675 0.386390786228784 GO:0008276 protein methyltransferase activity 27/3947 95/18639 0.284210526315789 1.34213326577147 0.0575923605247113 0.3866101033243 GO:0031369 translation initiation factor binding 11/3947 32/18639 0.34375 1.62329775779073 0.0589907750936185 0.391156366327362 GO:0120015 sterol transfer activity 11/3947 32/18639 0.34375 1.62329775779073 0.0589907750936185 0.391156366327362 GO:0140299 molecular sensor activity 21/3947 71/18639 0.295774647887324 1.39674275702352 0.0598578085750597 0.391156366327362 GO:0008173 RNA methyltransferase activity 20/3947 67/18639 0.298507462686567 1.40964798505572 0.0598687768150104 0.391156366327362 GO:0016922 nuclear receptor binding 37/3947 137/18639 0.27007299270073 1.27537129742815 0.0609696593107811 0.391156366327362 GO:0005225 volume-sensitive anion channel activity 5/3947 11/18639 0.454545454545455 2.14650943178939 0.0625965571482578 0.391156366327362 GO:0008172 S-methyltransferase activity 5/3947 11/18639 0.454545454545455 2.14650943178939 0.0625965571482578 0.391156366327362 GO:0015173 aromatic amino acid transmembrane transporter activity 5/3947 11/18639 0.454545454545455 2.14650943178939 0.0625965571482578 0.391156366327362 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 5/3947 11/18639 0.454545454545455 2.14650943178939 0.0625965571482578 0.391156366327362 GO:0032404 mismatch repair complex binding 5/3947 11/18639 0.454545454545455 2.14650943178939 0.0625965571482578 0.391156366327362 GO:0042608 T cell receptor binding 5/3947 11/18639 0.454545454545455 2.14650943178939 0.0625965571482578 0.391156366327362 GO:0048407 platelet-derived growth factor binding 5/3947 11/18639 0.454545454545455 2.14650943178939 0.0625965571482578 0.391156366327362 GO:0097493 structural molecule activity conferring elasticity 5/3947 11/18639 0.454545454545455 2.14650943178939 0.0625965571482578 0.391156366327362 GO:0140537 transcription regulator activator activity 5/3947 11/18639 0.454545454545455 2.14650943178939 0.0625965571482578 0.391156366327362 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 5/3947 11/18639 0.454545454545455 2.14650943178939 0.0625965571482578 0.391156366327362 GO:0019211 phosphatase activator activity 9/3947 25/18639 0.36 1.7000354699772 0.0641174806304677 0.395727119340842 GO:0004177 aminopeptidase activity 13/3947 40/18639 0.325 1.53475424372941 0.0642035149373047 0.395727119340842 GO:0015036 disulfide oxidoreductase activity 13/3947 40/18639 0.325 1.53475424372941 0.0642035149373047 0.395727119340842 GO:0043178 alcohol binding 26/3947 92/18639 0.282608695652174 1.3345689075908 0.0653043355389894 0.399657363236873 GO:0004540 RNA nuclease activity 33/3947 121/18639 0.272727272727273 1.28790565907363 0.0654306302644438 0.399657363236873 GO:0051117 ATPase binding 24/3947 84/18639 0.285714285714286 1.3492344999819 0.0667138925633117 0.402464631640641 GO:0008308 voltage-gated monoatomic anion channel activity 7/3947 18/18639 0.388888888888889 1.83645806941981 0.0669850957568549 0.402464631640641 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 7/3947 18/18639 0.388888888888889 1.83645806941981 0.0669850957568549 0.402464631640641 GO:0140693 molecular condensate scaffold activity 15/3947 48/18639 0.3125 1.47572523435521 0.0670774386067735 0.402464631640641 GO:0032934 sterol binding 20/3947 68/18639 0.294117647058824 1.38891786762843 0.0685435291830847 0.408798350520067 GO:0010484 histone H3 acetyltransferase activity 10/3947 29/18639 0.344827586206897 1.6283864654954 0.0687360058396574 0.408798350520067 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 11/3947 33/18639 0.333333333333333 1.57410691664555 0.0721683533926138 0.425479509566888 GO:0140416 transcription regulator inhibitor activity 11/3947 33/18639 0.333333333333333 1.57410691664555 0.0721683533926138 0.425479509566888 GO:0004407 histone deacetylase activity 8/3947 22/18639 0.363636363636364 1.71720754543151 0.0747426973992625 0.42949652588624 GO:0008649 rRNA methyltransferase activity 8/3947 22/18639 0.363636363636364 1.71720754543151 0.0747426973992625 0.42949652588624 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 8/3947 22/18639 0.363636363636364 1.71720754543151 0.0747426973992625 0.42949652588624 GO:0033558 protein lysine deacetylase activity 8/3947 22/18639 0.363636363636364 1.71720754543151 0.0747426973992625 0.42949652588624 GO:0140517 protein-RNA adaptor activity 8/3947 22/18639 0.363636363636364 1.71720754543151 0.0747426973992625 0.42949652588624 GO:0004842 ubiquitin-protein transferase activity 108/3947 449/18639 0.240534521158129 1.13588116034111 0.0747501328238589 0.42949652588624 GO:0030971 receptor tyrosine kinase binding 23/3947 81/18639 0.283950617283951 1.34090589195732 0.0758720864911641 0.433896369773411 GO:0031072 heat shock protein binding 35/3947 131/18639 0.267175572519084 1.26168874998308 0.076164017847785 0.433896369773411 GO:0140318 protein transporter activity 13/3947 41/18639 0.317073170731707 1.49732121339455 0.0764758350854315 0.433896369773411 GO:0004559 alpha-mannosidase activity 6/3947 15/18639 0.4 1.88892829997466 0.0773794016984123 0.435379538186917 GO:0050780 dopamine receptor binding 6/3947 15/18639 0.4 1.88892829997466 0.0773794016984123 0.435379538186917 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 18/3947 61/18639 0.295081967213115 1.39347169670262 0.078852823790755 0.441836483720098 GO:0004112 cyclic-nucleotide phosphodiesterase activity 9/3947 26/18639 0.346153846153846 1.63464949036269 0.0803146459162488 0.446338769928005 GO:0050681 nuclear androgen receptor binding 9/3947 26/18639 0.346153846153846 1.63464949036269 0.0803146459162488 0.446338769928005 GO:0015035 protein-disulfide reductase activity 11/3947 34/18639 0.323529411764706 1.52780965439127 0.0870756470433917 0.460887787906256 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 11/3947 34/18639 0.323529411764706 1.52780965439127 0.0870756470433917 0.460887787906256 GO:0052866 phosphatidylinositol phosphate phosphatase activity 11/3947 34/18639 0.323529411764706 1.52780965439127 0.0870756470433917 0.460887787906256 GO:0050145 nucleoside monophosphate kinase activity 7/3947 19/18639 0.368421052631579 1.73980238155561 0.08736514353713 0.460887787906256 GO:0005165 neurotrophin receptor binding 5/3947 12/18639 0.416666666666667 1.96763364580694 0.0891524716999045 0.460887787906256 GO:0005247 voltage-gated chloride channel activity 5/3947 12/18639 0.416666666666667 1.96763364580694 0.0891524716999045 0.460887787906256 GO:0016208 AMP binding 5/3947 12/18639 0.416666666666667 1.96763364580694 0.0891524716999045 0.460887787906256 GO:0016273 arginine N-methyltransferase activity 5/3947 12/18639 0.416666666666667 1.96763364580694 0.0891524716999045 0.460887787906256 GO:0016274 protein-arginine N-methyltransferase activity 5/3947 12/18639 0.416666666666667 1.96763364580694 0.0891524716999045 0.460887787906256 GO:0016801 hydrolase activity, acting on ether bonds 5/3947 12/18639 0.416666666666667 1.96763364580694 0.0891524716999045 0.460887787906256 GO:0016803 ether hydrolase activity 5/3947 12/18639 0.416666666666667 1.96763364580694 0.0891524716999045 0.460887787906256 GO:0035014 phosphatidylinositol 3-kinase regulator activity 5/3947 12/18639 0.416666666666667 1.96763364580694 0.0891524716999045 0.460887787906256 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 5/3947 12/18639 0.416666666666667 1.96763364580694 0.0891524716999045 0.460887787906256 GO:0097371 MDM2/MDM4 family protein binding 5/3947 12/18639 0.416666666666667 1.96763364580694 0.0891524716999045 0.460887787906256 GO:0141221 histone deacetylase activity, hydrolytic mechanism 5/3947 12/18639 0.416666666666667 1.96763364580694 0.0891524716999045 0.460887787906256 GO:1990459 transferrin receptor binding 5/3947 12/18639 0.416666666666667 1.96763364580694 0.0891524716999045 0.460887787906256 GO:1990817 poly(A) RNA polymerase activity 5/3947 12/18639 0.416666666666667 1.96763364580694 0.0891524716999045 0.460887787906256 GO:0008235 metalloexopeptidase activity 19/3947 66/18639 0.287878787878788 1.35945597346661 0.0892527633754648 0.460887787906256 GO:0016874 ligase activity 43/3947 167/18639 0.25748502994012 1.21592689968429 0.0893904780378653 0.460887787906256 GO:0015485 cholesterol binding 16/3947 54/18639 0.296296296296296 1.39920614812938 0.0909476659133381 0.467140284009418 GO:0003887 DNA-directed DNA polymerase activity 8/3947 23/18639 0.347826086956522 1.64254634780406 0.0941594662677284 0.478203132056329 GO:0017134 fibroblast growth factor binding 8/3947 23/18639 0.347826086956522 1.64254634780406 0.0941594662677284 0.478203132056329 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 8/3947 23/18639 0.347826086956522 1.64254634780406 0.0941594662677284 0.478203132056329 GO:0023026 MHC class II protein complex binding 9/3947 27/18639 0.333333333333333 1.57410691664555 0.0987606198018537 0.499405733191462 GO:1990782 protein tyrosine kinase binding 31/3947 117/18639 0.264957264957265 1.25121319015416 0.0990709013484537 0.499405733191462 GO:0050840 extracellular matrix binding 19/3947 67/18639 0.283582089552239 1.33916558580293 0.100883924722311 0.503601147739008 GO:0061630 ubiquitin protein ligase activity 85/3947 353/18639 0.240793201133144 1.13710273015472 0.101134386922666 0.503601147739008 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 34/3947 130/18639 0.261538461538462 1.23506850382959 0.101153548000186 0.503601147739008 GO:0140030 modification-dependent protein binding 44/3947 173/18639 0.254335260115607 1.20105267628447 0.10138872664657 0.503601147739008 GO:0016411 acylglycerol O-acyltransferase activity 10/3947 31/18639 0.32258064516129 1.52332927417312 0.10180807242508 0.503838489811712 GO:0004708 MAP kinase kinase activity 6/3947 16/18639 0.375 1.77087028122625 0.102441685451893 0.505130638082787 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 17/3947 59/18639 0.288135593220339 1.36066869065972 0.103209353648827 0.505946680483236 GO:0005154 epidermal growth factor receptor binding 11/3947 35/18639 0.314285714285714 1.48415794998009 0.103726531839484 0.505946680483236 GO:0043015 gamma-tubulin binding 11/3947 35/18639 0.314285714285714 1.48415794998009 0.103726531839484 0.505946680483236 GO:0003779 actin binding 105/3947 443/18639 0.237020316027088 1.11928595653126 0.105197283807606 0.507041831019444 GO:0008200 ion channel inhibitor activity 13/3947 43/18639 0.302325581395349 1.42767836625992 0.105257268739126 0.507041831019444 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 13/3947 43/18639 0.302325581395349 1.42767836625992 0.105257268739126 0.507041831019444 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 32/3947 122/18639 0.262295081967213 1.23864150818011 0.105802973486672 0.507041831019444 GO:0004527 exonuclease activity 23/3947 84/18639 0.273809523809524 1.29301639581599 0.105820677122789 0.507041831019444 GO:0042578 phosphoric ester hydrolase activity 87/3947 363/18639 0.239669421487603 1.13179588221622 0.106854612971555 0.510193152075452 GO:0005540 hyaluronic acid binding 8/3947 24/18639 0.333333333333333 1.57410691664555 0.11616519414864 0.542715416801624 GO:0043998 histone H2A acetyltransferase activity 8/3947 24/18639 0.333333333333333 1.57410691664555 0.11616519414864 0.542715416801624 GO:0050431 transforming growth factor beta binding 8/3947 24/18639 0.333333333333333 1.57410691664555 0.11616519414864 0.542715416801624 GO:0070840 dynein complex binding 8/3947 24/18639 0.333333333333333 1.57410691664555 0.11616519414864 0.542715416801624 GO:0004721 phosphoprotein phosphatase activity 44/3947 175/18639 0.251428571428571 1.18732635998407 0.116812624827074 0.542715416801624 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 17/3947 60/18639 0.283333333333333 1.33799087914872 0.116871013114181 0.542715416801624 GO:0008237 metallopeptidase activity 46/3947 184/18639 0.25 1.18058018748417 0.119125642717267 0.542715416801624 GO:0046625 sphingolipid binding 9/3947 28/18639 0.321428571428571 1.51788881247964 0.119427133656891 0.542715416801624 GO:0046966 nuclear thyroid hormone receptor binding 9/3947 28/18639 0.321428571428571 1.51788881247964 0.119427133656891 0.542715416801624 GO:0051019 mitogen-activated protein kinase binding 9/3947 28/18639 0.321428571428571 1.51788881247964 0.119427133656891 0.542715416801624 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 5/3947 13/18639 0.384615384615385 1.8162772115141 0.120556369685968 0.542715416801624 GO:0005542 folic acid binding 5/3947 13/18639 0.384615384615385 1.8162772115141 0.120556369685968 0.542715416801624 GO:0019104 DNA N-glycosylase activity 5/3947 13/18639 0.384615384615385 1.8162772115141 0.120556369685968 0.542715416801624 GO:0070700 BMP receptor binding 5/3947 13/18639 0.384615384615385 1.8162772115141 0.120556369685968 0.542715416801624 GO:0001221 transcription coregulator binding 30/3947 115/18639 0.260869565217391 1.23190976085304 0.120662795910889 0.542715416801624 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 14/3947 48/18639 0.291666666666667 1.37734355206486 0.120932525551874 0.542715416801624 GO:0042626 ATPase-coupled transmembrane transporter activity 26/3947 98/18639 0.26530612244898 1.25286060712605 0.12106487626179 0.542715416801624 GO:0022884 macromolecule transmembrane transporter activity 10/3947 32/18639 0.3125 1.47572523435521 0.121270480303018 0.542715416801624 GO:0043425 bHLH transcription factor binding 10/3947 32/18639 0.3125 1.47572523435521 0.121270480303018 0.542715416801624 GO:0016248 channel inhibitor activity 13/3947 44/18639 0.295454545454545 1.3952311306631 0.121772595173555 0.54316986531362 GO:0004532 RNA exonuclease activity 12/3947 40/18639 0.3 1.416696224981 0.122209330041501 0.543330660774671 GO:0004521 RNA endonuclease activity 20/3947 73/18639 0.273972602739726 1.29378650683196 0.124474944160066 0.551594850591667 GO:0016791 phosphatase activity 66/3947 273/18639 0.241758241758242 1.14165996152315 0.12636944316821 0.554130880851574 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 56/3947 229/18639 0.244541484716157 1.15480332749543 0.12788053567621 0.554130880851574 GO:0032182 ubiquitin-like protein binding 31/3947 120/18639 0.258333333333333 1.2199328604003 0.128058222190226 0.554130880851574 GO:0160215 deacylase activity 18/3947 65/18639 0.276923076923077 1.30771959229015 0.129239909712951 0.554130880851574 GO:0004549 tRNA-specific ribonuclease activity 6/3947 17/18639 0.352941176470588 1.66670144115412 0.131181470571454 0.554130880851574 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 6/3947 17/18639 0.352941176470588 1.66670144115412 0.131181470571454 0.554130880851574 GO:0016805 dipeptidase activity 6/3947 17/18639 0.352941176470588 1.66670144115412 0.131181470571454 0.554130880851574 GO:0019198 transmembrane receptor protein phosphatase activity 6/3947 17/18639 0.352941176470588 1.66670144115412 0.131181470571454 0.554130880851574 GO:0070402 NADPH binding 6/3947 17/18639 0.352941176470588 1.66670144115412 0.131181470571454 0.554130880851574 GO:0004601 peroxidase activity 16/3947 57/18639 0.280701754385965 1.32556371928047 0.133804586439939 0.554130880851574 GO:0140296 general transcription initiation factor binding 15/3947 53/18639 0.283018867924528 1.33650587262358 0.135939141244951 0.554130880851574 GO:0009931 calcium-dependent protein serine/threonine kinase activity 7/3947 21/18639 0.333333333333333 1.57410691664555 0.137297263508669 0.554130880851574 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 7/3947 21/18639 0.333333333333333 1.57410691664555 0.137297263508669 0.554130880851574 GO:0051010 microtubule plus-end binding 7/3947 21/18639 0.333333333333333 1.57410691664555 0.137297263508669 0.554130880851574 GO:1904047 S-adenosyl-L-methionine binding 7/3947 21/18639 0.333333333333333 1.57410691664555 0.137297263508669 0.554130880851574 GO:0001222 transcription corepressor binding 14/3947 49/18639 0.285714285714286 1.3492344999819 0.137917257184197 0.554130880851574 GO:0016763 pentosyltransferase activity 14/3947 49/18639 0.285714285714286 1.3492344999819 0.137917257184197 0.554130880851574 GO:0141110 transporter inhibitor activity 13/3947 45/18639 0.288888888888889 1.36422599442615 0.139676892090783 0.554130880851574 GO:0017025 TBP-class protein binding 8/3947 25/18639 0.32 1.51114263997973 0.14065823580425 0.554130880851574 GO:0001727 lipid kinase activity 12/3947 41/18639 0.292682926829268 1.38214265851805 0.141133534850908 0.554130880851574 GO:0016877 ligase activity, forming carbon-sulfur bonds 12/3947 41/18639 0.292682926829268 1.38214265851805 0.141133534850908 0.554130880851574 GO:0140098 catalytic activity, acting on RNA 91/3947 387/18639 0.235142118863049 1.11041650709105 0.141553236035178 0.554130880851574 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 9/3947 29/18639 0.310344827586207 1.46554781894586 0.142238141174646 0.554130880851574 GO:0001094 TFIID-class transcription factor complex binding 4/3947 10/18639 0.4 1.88892829997466 0.142433899132361 0.554130880851574 GO:0008190 eukaryotic initiation factor 4E binding 4/3947 10/18639 0.4 1.88892829997466 0.142433899132361 0.554130880851574 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 4/3947 10/18639 0.4 1.88892829997466 0.142433899132361 0.554130880851574 GO:0008641 ubiquitin-like modifier activating enzyme activity 4/3947 10/18639 0.4 1.88892829997466 0.142433899132361 0.554130880851574 GO:0015924 mannosyl-oligosaccharide mannosidase activity 4/3947 10/18639 0.4 1.88892829997466 0.142433899132361 0.554130880851574 GO:0016175 superoxide-generating NAD(P)H oxidase activity 4/3947 10/18639 0.4 1.88892829997466 0.142433899132361 0.554130880851574 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 4/3947 10/18639 0.4 1.88892829997466 0.142433899132361 0.554130880851574 GO:0031434 mitogen-activated protein kinase kinase binding 4/3947 10/18639 0.4 1.88892829997466 0.142433899132361 0.554130880851574 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 4/3947 10/18639 0.4 1.88892829997466 0.142433899132361 0.554130880851574 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 4/3947 10/18639 0.4 1.88892829997466 0.142433899132361 0.554130880851574 GO:0042975 peroxisome proliferator activated receptor binding 4/3947 10/18639 0.4 1.88892829997466 0.142433899132361 0.554130880851574 GO:0043295 glutathione binding 4/3947 10/18639 0.4 1.88892829997466 0.142433899132361 0.554130880851574 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 4/3947 10/18639 0.4 1.88892829997466 0.142433899132361 0.554130880851574 GO:0051880 G-quadruplex DNA binding 4/3947 10/18639 0.4 1.88892829997466 0.142433899132361 0.554130880851574 GO:0140940 histone H2A methyltransferase activity 4/3947 10/18639 0.4 1.88892829997466 0.142433899132361 0.554130880851574 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 4/3947 10/18639 0.4 1.88892829997466 0.142433899132361 0.554130880851574 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 4/3947 10/18639 0.4 1.88892829997466 0.142433899132361 0.554130880851574 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 4/3947 10/18639 0.4 1.88892829997466 0.142433899132361 0.554130880851574 GO:1990259 histone H2AQ104 methyltransferase activity 4/3947 10/18639 0.4 1.88892829997466 0.142433899132361 0.554130880851574 GO:0071889 14-3-3 protein binding 10/3947 33/18639 0.303030303030303 1.43100628785959 0.142619231133628 0.554130880851574 GO:0004518 nuclease activity 51/3947 209/18639 0.244019138755981 1.15233664232904 0.144282277126378 0.557398198813014 GO:0051015 actin filament binding 51/3947 209/18639 0.244019138755981 1.15233664232904 0.144282277126378 0.557398198813014 GO:0043130 ubiquitin binding 26/3947 100/18639 0.26 1.22780339498353 0.14471259919928 0.557472399188135 GO:0045296 cadherin binding 79/3947 334/18639 0.236526946107784 1.11695610552394 0.147001419992643 0.564685341388169 GO:0005543 phospholipid binding 115/3947 497/18639 0.231388329979879 1.09268991195718 0.151614579047544 0.573483934149157 GO:0004857 enzyme inhibitor activity 97/3947 416/18639 0.233173076923077 1.10111805948042 0.153821866629007 0.573483934149157 GO:0032813 tumor necrosis factor receptor superfamily binding 14/3947 50/18639 0.28 1.32224980998227 0.156144373562794 0.573483934149157 GO:0005545 1-phosphatidylinositol binding 5/3947 14/18639 0.357142857142857 1.68654312497738 0.156317330435908 0.573483934149157 GO:0008174 mRNA methyltransferase activity 5/3947 14/18639 0.357142857142857 1.68654312497738 0.156317330435908 0.573483934149157 GO:0034236 protein kinase A catalytic subunit binding 5/3947 14/18639 0.357142857142857 1.68654312497738 0.156317330435908 0.573483934149157 GO:0030291 protein serine/threonine kinase inhibitor activity 13/3947 46/18639 0.282608695652174 1.3345689075908 0.158926282862481 0.573483934149157 GO:0042054 histone methyltransferase activity 18/3947 67/18639 0.26865671641791 1.26868318655015 0.160160007295826 0.573483934149157 GO:0002020 protease binding 34/3947 136/18639 0.25 1.18058018748417 0.160804276819034 0.573483934149157 GO:0140789 histone phosphatase activity 34/3947 136/18639 0.25 1.18058018748417 0.160804276819034 0.573483934149157 GO:0016859 cis-trans isomerase activity 12/3947 42/18639 0.285714285714286 1.3492344999819 0.161524455415726 0.573483934149157 GO:0000400 four-way junction DNA binding 6/3947 18/18639 0.333333333333333 1.57410691664555 0.163279657978753 0.573483934149157 GO:0003746 translation elongation factor activity 6/3947 18/18639 0.333333333333333 1.57410691664555 0.163279657978753 0.573483934149157 GO:0008409 5'-3' exonuclease activity 6/3947 18/18639 0.333333333333333 1.57410691664555 0.163279657978753 0.573483934149157 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 6/3947 18/18639 0.333333333333333 1.57410691664555 0.163279657978753 0.573483934149157 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 11/3947 38/18639 0.289473684210526 1.36698758550798 0.163847275367702 0.573483934149157 GO:0043531 ADP binding 11/3947 38/18639 0.289473684210526 1.36698758550798 0.163847275367702 0.573483934149157 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 33/3947 132/18639 0.25 1.18058018748417 0.165049690290532 0.573483934149157 GO:0008175 tRNA methyltransferase activity 10/3947 34/18639 0.294117647058824 1.38891786762843 0.165762391171227 0.573483934149157 GO:0030332 cyclin binding 10/3947 34/18639 0.294117647058824 1.38891786762843 0.165762391171227 0.573483934149157 GO:0008970 phospholipase A1 activity 7/3947 22/18639 0.318181818181818 1.50255660225257 0.166489394359726 0.573483934149157 GO:0031683 G-protein beta/gamma-subunit complex binding 7/3947 22/18639 0.318181818181818 1.50255660225257 0.166489394359726 0.573483934149157 GO:0032931 histone H3K56 acetyltransferase activity 7/3947 22/18639 0.318181818181818 1.50255660225257 0.166489394359726 0.573483934149157 GO:0043992 histone H3K9 acetyltransferase activity 7/3947 22/18639 0.318181818181818 1.50255660225257 0.166489394359726 0.573483934149157 GO:0043993 histone H3K18 acetyltransferase activity 7/3947 22/18639 0.318181818181818 1.50255660225257 0.166489394359726 0.573483934149157 GO:0043994 histone H3K23 acetyltransferase activity 7/3947 22/18639 0.318181818181818 1.50255660225257 0.166489394359726 0.573483934149157 GO:0043999 histone H2AK5 acetyltransferase activity 7/3947 22/18639 0.318181818181818 1.50255660225257 0.166489394359726 0.573483934149157 GO:0044012 histone H2AK9 acetyltransferase activity 7/3947 22/18639 0.318181818181818 1.50255660225257 0.166489394359726 0.573483934149157 GO:0044014 histone H2BK5 acetyltransferase activity 7/3947 22/18639 0.318181818181818 1.50255660225257 0.166489394359726 0.573483934149157 GO:0044015 histone H2BK12 acetyltransferase activity 7/3947 22/18639 0.318181818181818 1.50255660225257 0.166489394359726 0.573483934149157 GO:0044016 histone H3K4 acetyltransferase activity 7/3947 22/18639 0.318181818181818 1.50255660225257 0.166489394359726 0.573483934149157 GO:0044017 histone H3K27 acetyltransferase activity 7/3947 22/18639 0.318181818181818 1.50255660225257 0.166489394359726 0.573483934149157 GO:0044018 histone H3K36 acetyltransferase activity 7/3947 22/18639 0.318181818181818 1.50255660225257 0.166489394359726 0.573483934149157 GO:0046972 histone H4K16 acetyltransferase activity 7/3947 22/18639 0.318181818181818 1.50255660225257 0.166489394359726 0.573483934149157 GO:0070034 telomerase RNA binding 7/3947 22/18639 0.318181818181818 1.50255660225257 0.166489394359726 0.573483934149157 GO:0140908 histone H3K122 acetyltransferase activity 7/3947 22/18639 0.318181818181818 1.50255660225257 0.166489394359726 0.573483934149157 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 9/3947 30/18639 0.3 1.416696224981 0.167073252780578 0.573483934149157 GO:0070566 adenylyltransferase activity 9/3947 30/18639 0.3 1.416696224981 0.167073252780578 0.573483934149157 GO:0005160 transforming growth factor beta receptor binding 8/3947 26/18639 0.307692307692308 1.45302176921128 0.167477609087807 0.573483934149157 GO:0008157 protein phosphatase 1 binding 8/3947 26/18639 0.307692307692308 1.45302176921128 0.167477609087807 0.573483934149157 GO:0050750 low-density lipoprotein particle receptor binding 8/3947 26/18639 0.307692307692308 1.45302176921128 0.167477609087807 0.573483934149157 GO:0070412 R-SMAD binding 8/3947 26/18639 0.307692307692308 1.45302176921128 0.167477609087807 0.573483934149157 GO:0097602 cullin family protein binding 8/3947 26/18639 0.307692307692308 1.45302176921128 0.167477609087807 0.573483934149157 GO:0035401 histone H3Y41 kinase activity 29/3947 115/18639 0.252173913043478 1.19084610215794 0.170484686638627 0.580847324326577 GO:0140801 histone H2AXY142 kinase activity 29/3947 115/18639 0.252173913043478 1.19084610215794 0.170484686638627 0.580847324326577 GO:0140313 molecular sequestering activity 15/3947 55/18639 0.272727272727273 1.28790565907363 0.171662070983245 0.583392902890428 GO:0005126 cytokine receptor binding 65/3947 275/18639 0.236363636363636 1.11618490453048 0.175215580603229 0.593353265498299 GO:0004725 protein tyrosine phosphatase activity 25/3947 98/18639 0.255102040816327 1.20467366069813 0.175468037953406 0.593353265498299 GO:0106310 protein serine kinase activity 84/3947 361/18639 0.232686980609418 1.09882255677197 0.178854577401404 0.603300514816675 GO:0016410 N-acyltransferase activity 24/3947 94/18639 0.25531914893617 1.20569891487745 0.180256041452888 0.606519087370014 GO:0004722 protein serine/threonine phosphatase activity 26/3947 103/18639 0.252427184466019 1.19204213105197 0.18481786243525 0.611517750423484 GO:0098531 ligand-modulated transcription factor activity 16/3947 60/18639 0.266666666666667 1.25928553331644 0.18629458663514 0.611517750423484 GO:0000217 DNA secondary structure binding 11/3947 39/18639 0.282051282051282 1.33193662177701 0.187041439240276 0.611517750423484 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 11/3947 39/18639 0.282051282051282 1.33193662177701 0.187041439240276 0.611517750423484 GO:0001851 complement component C3b binding 4/3947 11/18639 0.363636363636364 1.71720754543151 0.188055237408992 0.611517750423484 GO:0005114 type II transforming growth factor beta receptor binding 4/3947 11/18639 0.363636363636364 1.71720754543151 0.188055237408992 0.611517750423484 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 4/3947 11/18639 0.363636363636364 1.71720754543151 0.188055237408992 0.611517750423484 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 4/3947 11/18639 0.363636363636364 1.71720754543151 0.188055237408992 0.611517750423484 GO:0019206 nucleoside kinase activity 4/3947 11/18639 0.363636363636364 1.71720754543151 0.188055237408992 0.611517750423484 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 4/3947 11/18639 0.363636363636364 1.71720754543151 0.188055237408992 0.611517750423484 GO:0032794 GTPase activating protein binding 4/3947 11/18639 0.363636363636364 1.71720754543151 0.188055237408992 0.611517750423484 GO:0034511 U3 snoRNA binding 4/3947 11/18639 0.363636363636364 1.71720754543151 0.188055237408992 0.611517750423484 GO:0034713 type I transforming growth factor beta receptor binding 4/3947 11/18639 0.363636363636364 1.71720754543151 0.188055237408992 0.611517750423484 GO:1900750 oligopeptide binding 4/3947 11/18639 0.363636363636364 1.71720754543151 0.188055237408992 0.611517750423484 GO:0061631 ubiquitin conjugating enzyme activity 10/3947 35/18639 0.285714285714286 1.3492344999819 0.190576734903924 0.61537305058027 GO:0030170 pyridoxal phosphate binding 15/3947 56/18639 0.267857142857143 1.26490734373303 0.191142171127093 0.61537305058027 GO:0005164 tumor necrosis factor receptor binding 9/3947 31/18639 0.290322580645161 1.3709963467558 0.193772644744191 0.61537305058027 GO:0070325 lipoprotein particle receptor binding 9/3947 31/18639 0.290322580645161 1.3709963467558 0.193772644744191 0.61537305058027 GO:0016798 hydrolase activity, acting on glycosyl bonds 32/3947 130/18639 0.246153846153846 1.16241741536902 0.194573314769093 0.61537305058027 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 5/3947 15/18639 0.333333333333333 1.57410691664555 0.195786294804656 0.61537305058027 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 5/3947 15/18639 0.333333333333333 1.57410691664555 0.195786294804656 0.61537305058027 GO:0015556 C4-dicarboxylate transmembrane transporter activity 5/3947 15/18639 0.333333333333333 1.57410691664555 0.195786294804656 0.61537305058027 GO:0004364 glutathione transferase activity 8/3947 27/18639 0.296296296296296 1.39920614812938 0.19641107826084 0.61537305058027 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 8/3947 27/18639 0.296296296296296 1.39920614812938 0.19641107826084 0.61537305058027 GO:0030295 protein kinase activator activity 34/3947 139/18639 0.244604316546763 1.15510003955285 0.196859638157662 0.61537305058027 GO:0070851 growth factor receptor binding 34/3947 139/18639 0.244604316546763 1.15510003955285 0.196859638157662 0.61537305058027 GO:0008171 O-methyltransferase activity 7/3947 23/18639 0.304347826086957 1.43722805432855 0.198133737899975 0.61537305058027 GO:0016849 phosphorus-oxygen lyase activity 7/3947 23/18639 0.304347826086957 1.43722805432855 0.198133737899975 0.61537305058027 GO:0031681 G-protein beta-subunit binding 7/3947 23/18639 0.304347826086957 1.43722805432855 0.198133737899975 0.61537305058027 GO:0043274 phospholipase binding 7/3947 23/18639 0.304347826086957 1.43722805432855 0.198133737899975 0.61537305058027 GO:0044013 histone H2B acetyltransferase activity 7/3947 23/18639 0.304347826086957 1.43722805432855 0.198133737899975 0.61537305058027 GO:0070003 threonine-type peptidase activity 6/3947 19/18639 0.315789473684211 1.49125918419052 0.19831712618258 0.61537305058027 GO:0097001 ceramide binding 6/3947 19/18639 0.315789473684211 1.49125918419052 0.19831712618258 0.61537305058027 GO:1990380 K48-linked deubiquitinase activity 6/3947 19/18639 0.315789473684211 1.49125918419052 0.19831712618258 0.61537305058027 GO:0019209 kinase activator activity 36/3947 148/18639 0.243243243243243 1.14867261484946 0.198784387255787 0.615414678353534 GO:0016836 hydro-lyase activity 16/3947 61/18639 0.262295081967213 1.23864150818011 0.205755823131495 0.634583607013764 GO:0001223 transcription coactivator binding 12/3947 44/18639 0.272727272727273 1.28790565907363 0.206380066882795 0.634583607013764 GO:0030020 extracellular matrix structural constituent conferring tensile strength 12/3947 44/18639 0.272727272727273 1.28790565907363 0.206380066882795 0.634583607013764 GO:0004713 protein tyrosine kinase activity 34/3947 140/18639 0.242857142857143 1.14684932498462 0.20974155354644 0.643460512689982 GO:0070279 vitamin B6 binding 15/3947 57/18639 0.263157894736842 1.24271598682544 0.211619879943933 0.647757465471724 GO:1901981 phosphatidylinositol phosphate binding 44/3947 185/18639 0.237837837837838 1.12314655674169 0.215138272032419 0.656545606932371 GO:0005484 SNAP receptor activity 10/3947 36/18639 0.277777777777778 1.31175576387129 0.216911682068846 0.656545606932371 GO:0044390 ubiquitin-like protein conjugating enzyme binding 10/3947 36/18639 0.277777777777778 1.31175576387129 0.216911682068846 0.656545606932371 GO:0019902 phosphatase binding 45/3947 190/18639 0.236842105263158 1.11844438814289 0.221127749163304 0.656545606932371 GO:0051059 NF-kappaB binding 9/3947 32/18639 0.28125 1.32815271091969 0.222143056916824 0.656545606932371 GO:0071813 lipoprotein particle binding 9/3947 32/18639 0.28125 1.32815271091969 0.222143056916824 0.656545606932371 GO:0071814 protein-lipid complex binding 9/3947 32/18639 0.28125 1.32815271091969 0.222143056916824 0.656545606932371 GO:0019842 vitamin binding 36/3947 150/18639 0.24 1.1333569799848 0.224240047293671 0.656545606932371 GO:0016247 channel regulator activity 40/3947 168/18639 0.238095238095238 1.12436208331825 0.225910127658541 0.656545606932371 GO:0008009 chemokine activity 12/3947 45/18639 0.266666666666667 1.25928553331644 0.230635766807163 0.656545606932371 GO:0001091 RNA polymerase II general transcription initiation factor binding 7/3947 24/18639 0.291666666666667 1.37734355206486 0.231885491209348 0.656545606932371 GO:0004622 lysophospholipase activity 7/3947 24/18639 0.291666666666667 1.37734355206486 0.231885491209348 0.656545606932371 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 7/3947 24/18639 0.291666666666667 1.37734355206486 0.231885491209348 0.656545606932371 GO:0140612 DNA damage sensor activity 7/3947 24/18639 0.291666666666667 1.37734355206486 0.231885491209348 0.656545606932371 GO:0016408 C-acyltransferase activity 6/3947 20/18639 0.3 1.416696224981 0.235803641908816 0.656545606932371 GO:0030742 GTP-dependent protein binding 6/3947 20/18639 0.3 1.416696224981 0.235803641908816 0.656545606932371 GO:0140664 ATP-dependent DNA damage sensor activity 6/3947 20/18639 0.3 1.416696224981 0.235803641908816 0.656545606932371 GO:0140939 histone H4 methyltransferase activity 6/3947 20/18639 0.3 1.416696224981 0.235803641908816 0.656545606932371 GO:0008238 exopeptidase activity 25/3947 102/18639 0.245098039215686 1.15743155635702 0.236870565630596 0.656545606932371 GO:0048306 calcium-dependent protein binding 20/3947 80/18639 0.25 1.18058018748417 0.237303439630984 0.656545606932371 GO:0001530 lipopolysaccharide binding 11/3947 41/18639 0.268292682926829 1.26696410364154 0.237482706767695 0.656545606932371 GO:0061650 ubiquitin-like protein conjugating enzyme activity 11/3947 41/18639 0.268292682926829 1.26696410364154 0.237482706767695 0.656545606932371 GO:0000995 RNA polymerase III general transcription initiation factor activity 4/3947 12/18639 0.333333333333333 1.57410691664555 0.237506620263536 0.656545606932371 GO:0004875 complement receptor activity 4/3947 12/18639 0.333333333333333 1.57410691664555 0.237506620263536 0.656545606932371 GO:0005025 transforming growth factor beta receptor activity, type I 4/3947 12/18639 0.333333333333333 1.57410691664555 0.237506620263536 0.656545606932371 GO:0005026 transforming growth factor beta receptor activity, type II 4/3947 12/18639 0.333333333333333 1.57410691664555 0.237506620263536 0.656545606932371 GO:0005095 GTPase inhibitor activity 4/3947 12/18639 0.333333333333333 1.57410691664555 0.237506620263536 0.656545606932371 GO:0010853 cyclase activator activity 4/3947 12/18639 0.333333333333333 1.57410691664555 0.237506620263536 0.656545606932371 GO:0016361 activin receptor activity, type I 4/3947 12/18639 0.333333333333333 1.57410691664555 0.237506620263536 0.656545606932371 GO:0016362 activin receptor activity, type II 4/3947 12/18639 0.333333333333333 1.57410691664555 0.237506620263536 0.656545606932371 GO:0016423 tRNA (guanine) methyltransferase activity 4/3947 12/18639 0.333333333333333 1.57410691664555 0.237506620263536 0.656545606932371 GO:0017002 activin receptor activity 4/3947 12/18639 0.333333333333333 1.57410691664555 0.237506620263536 0.656545606932371 GO:0034452 dynactin binding 4/3947 12/18639 0.333333333333333 1.57410691664555 0.237506620263536 0.656545606932371 GO:0036009 protein-glutamine N-methyltransferase activity 4/3947 12/18639 0.333333333333333 1.57410691664555 0.237506620263536 0.656545606932371 GO:0043047 single-stranded telomeric DNA binding 4/3947 12/18639 0.333333333333333 1.57410691664555 0.237506620263536 0.656545606932371 GO:0070410 co-SMAD binding 4/3947 12/18639 0.333333333333333 1.57410691664555 0.237506620263536 0.656545606932371 GO:0070679 inositol 1,4,5 trisphosphate binding 4/3947 12/18639 0.333333333333333 1.57410691664555 0.237506620263536 0.656545606932371 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 4/3947 12/18639 0.333333333333333 1.57410691664555 0.237506620263536 0.656545606932371 GO:0003688 DNA replication origin binding 5/3947 16/18639 0.3125 1.47572523435521 0.238215662692276 0.656545606932371 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 5/3947 16/18639 0.3125 1.47572523435521 0.238215662692276 0.656545606932371 GO:0005024 transforming growth factor beta receptor activity 5/3947 16/18639 0.3125 1.47572523435521 0.238215662692276 0.656545606932371 GO:0005149 interleukin-1 receptor binding 5/3947 16/18639 0.3125 1.47572523435521 0.238215662692276 0.656545606932371 GO:0005159 insulin-like growth factor receptor binding 5/3947 16/18639 0.3125 1.47572523435521 0.238215662692276 0.656545606932371 GO:0017070 U6 snRNA binding 5/3947 16/18639 0.3125 1.47572523435521 0.238215662692276 0.656545606932371 GO:0030275 LRR domain binding 5/3947 16/18639 0.3125 1.47572523435521 0.238215662692276 0.656545606932371 GO:0031435 mitogen-activated protein kinase kinase kinase binding 5/3947 16/18639 0.3125 1.47572523435521 0.238215662692276 0.656545606932371 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 5/3947 16/18639 0.3125 1.47572523435521 0.238215662692276 0.656545606932371 GO:0070411 I-SMAD binding 5/3947 16/18639 0.3125 1.47572523435521 0.238215662692276 0.656545606932371 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 5/3947 16/18639 0.3125 1.47572523435521 0.238215662692276 0.656545606932371 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 22/3947 89/18639 0.247191011235955 1.16731524155738 0.241055566522916 0.661682891103388 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 22/3947 89/18639 0.247191011235955 1.16731524155738 0.241055566522916 0.661682891103388 GO:0035173 histone kinase activity 82/3947 360/18639 0.227777777777778 1.07563972637446 0.244360345295175 0.668687987704092 GO:0023023 MHC protein complex binding 10/3947 37/18639 0.27027027027027 1.27630290538829 0.244593836210346 0.668687987704092 GO:0141108 transporter regulator activity 40/3947 170/18639 0.235294117647059 1.11113429410274 0.251386634319012 0.685875807115857 GO:0019956 chemokine binding 9/3947 33/18639 0.272727272727273 1.28790565907363 0.251964491585522 0.686071989136483 GO:0004879 nuclear receptor activity 15/3947 59/18639 0.254237288135593 1.20059002117034 0.255261457095297 0.693656384411267 GO:0140793 histone H2AXY142 phosphatase activity 22/3947 90/18639 0.244444444444444 1.15434507220674 0.259118948056186 0.702556462418875 GO:0099604 ligand-gated calcium channel activity 8/3947 29/18639 0.275862068965517 1.30270917239632 0.259572852265381 0.702556462418875 GO:0005496 steroid binding 26/3947 108/18639 0.240740740740741 1.13685499535512 0.262779670680509 0.709819190125039 GO:0008374 O-acyltransferase activity 14/3947 55/18639 0.254545454545455 1.20204528180206 0.263708392130783 0.710870389732348 GO:0042056 chemoattractant activity 11/3947 42/18639 0.261904761904762 1.23679829165008 0.264435634666781 0.710870389732348 GO:0016209 antioxidant activity 21/3947 86/18639 0.244186046511628 1.15312483428686 0.267244942624191 0.710870389732348 GO:0008139 nuclear localization sequence binding 7/3947 25/18639 0.28 1.32224980998227 0.267362757200219 0.710870389732348 GO:0015645 fatty acid ligase activity 7/3947 25/18639 0.28 1.32224980998227 0.267362757200219 0.710870389732348 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 7/3947 25/18639 0.28 1.32224980998227 0.267362757200219 0.710870389732348 GO:0120020 cholesterol transfer activity 7/3947 25/18639 0.28 1.32224980998227 0.267362757200219 0.710870389732348 GO:0120515 fatty acid-CoA ligase activity 7/3947 25/18639 0.28 1.32224980998227 0.267362757200219 0.710870389732348 GO:0042887 amide transmembrane transporter activity 10/3947 38/18639 0.263157894736842 1.24271598682544 0.273431893654148 0.725584437955039 GO:0001846 opsonin binding 6/3947 21/18639 0.285714285714286 1.3492344999819 0.275206193268875 0.727445610277962 GO:0005123 death receptor binding 6/3947 21/18639 0.285714285714286 1.3492344999819 0.275206193268875 0.727445610277962 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 15/3947 60/18639 0.25 1.18058018748417 0.278250413915349 0.734061403247496 GO:0004674 protein serine/threonine kinase activity 97/3947 433/18639 0.224018475750577 1.05788709640613 0.281134960823041 0.735142275724541 GO:0002039 p53 binding 17/3947 69/18639 0.246376811594203 1.16347032969454 0.282106231686318 0.735142275724541 GO:0016279 protein-lysine N-methyltransferase activity 17/3947 69/18639 0.246376811594203 1.16347032969454 0.282106231686318 0.735142275724541 GO:0004659 prenyltransferase activity 5/3947 17/18639 0.294117647058824 1.38891786762843 0.282813242742619 0.735142275724541 GO:0048038 quinone binding 5/3947 17/18639 0.294117647058824 1.38891786762843 0.282813242742619 0.735142275724541 GO:0051787 misfolded protein binding 5/3947 17/18639 0.294117647058824 1.38891786762843 0.282813242742619 0.735142275724541 GO:1990226 histone methyltransferase binding 5/3947 17/18639 0.294117647058824 1.38891786762843 0.282813242742619 0.735142275724541 GO:0008376 acetylgalactosaminyltransferase activity 9/3947 34/18639 0.264705882352941 1.25002608086559 0.282997247734668 0.735142275724541 GO:0008081 phosphoric diester hydrolase activity 21/3947 87/18639 0.241379310344828 1.13987052584678 0.286526422781098 0.736474661836339 GO:0019212 phosphatase inhibitor activity 14/3947 56/18639 0.25 1.18058018748417 0.287897132465347 0.736474661836339 GO:0005172 vascular endothelial growth factor receptor binding 4/3947 13/18639 0.307692307692308 1.45302176921128 0.289484509409121 0.736474661836339 GO:0005338 nucleotide-sugar transmembrane transporter activity 4/3947 13/18639 0.307692307692308 1.45302176921128 0.289484509409121 0.736474661836339 GO:0008253 5'-nucleotidase activity 4/3947 13/18639 0.307692307692308 1.45302176921128 0.289484509409121 0.736474661836339 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 4/3947 13/18639 0.307692307692308 1.45302176921128 0.289484509409121 0.736474661836339 GO:0019855 calcium channel inhibitor activity 4/3947 13/18639 0.307692307692308 1.45302176921128 0.289484509409121 0.736474661836339 GO:0039706 co-receptor binding 4/3947 13/18639 0.307692307692308 1.45302176921128 0.289484509409121 0.736474661836339 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 4/3947 13/18639 0.307692307692308 1.45302176921128 0.289484509409121 0.736474661836339 GO:0070123 transforming growth factor beta receptor activity, type III 4/3947 13/18639 0.307692307692308 1.45302176921128 0.289484509409121 0.736474661836339 GO:0097157 pre-mRNA intronic binding 4/3947 13/18639 0.307692307692308 1.45302176921128 0.289484509409121 0.736474661836339 GO:0048156 tau protein binding 11/3947 43/18639 0.255813953488372 1.20803554068147 0.292324186565268 0.740393853393598 GO:0016769 transferase activity, transferring nitrogenous groups 8/3947 30/18639 0.266666666666667 1.25928553331644 0.293209070259854 0.740393853393598 GO:0031624 ubiquitin conjugating enzyme binding 8/3947 30/18639 0.266666666666667 1.25928553331644 0.293209070259854 0.740393853393598 GO:0035925 mRNA 3'-UTR AU-rich region binding 8/3947 30/18639 0.266666666666667 1.25928553331644 0.293209070259854 0.740393853393598 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 30/3947 128/18639 0.234375 1.1067939257664 0.296443127445679 0.747168923450448 GO:0030159 signaling receptor complex adaptor activity 13/3947 52/18639 0.25 1.18058018748417 0.298170713420417 0.750128919105911 GO:0099106 ion channel regulator activity 37/3947 160/18639 0.23125 1.09203667342285 0.300742287850765 0.754144133303006 GO:0140996 histone H3 kinase activity 80/3947 357/18639 0.224089635854342 1.05822313724071 0.301817294142331 0.754144133303006 GO:0004529 DNA exonuclease activity 7/3947 26/18639 0.269230769230769 1.27139404805987 0.304162548610056 0.754144133303006 GO:0005112 Notch binding 7/3947 26/18639 0.269230769230769 1.27139404805987 0.304162548610056 0.754144133303006 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 7/3947 26/18639 0.269230769230769 1.27139404805987 0.304162548610056 0.754144133303006 GO:0034237 protein kinase A regulatory subunit binding 7/3947 26/18639 0.269230769230769 1.27139404805987 0.304162548610056 0.754144133303006 GO:0016278 lysine N-methyltransferase activity 17/3947 70/18639 0.242857142857143 1.14684932498462 0.30421595937813 0.754144133303006 GO:0097110 scaffold protein binding 17/3947 70/18639 0.242857142857143 1.14684932498462 0.30421595937813 0.754144133303006 GO:0140375 immune receptor activity 36/3947 156/18639 0.230769230769231 1.08976632690846 0.30881909789734 0.763605915954621 GO:0016879 ligase activity, forming carbon-nitrogen bonds 12/3947 48/18639 0.25 1.18058018748417 0.309159032344459 0.763605915954621 GO:0000175 3'-5'-RNA exonuclease activity 9/3947 35/18639 0.257142857142857 1.21431104998371 0.314988963714542 0.775181551355569 GO:0034061 DNA polymerase activity 9/3947 35/18639 0.257142857142857 1.21431104998371 0.314988963714542 0.775181551355569 GO:0003725 double-stranded RNA binding 18/3947 75/18639 0.24 1.1333569799848 0.31589825691111 0.776010935455552 GO:0005246 calcium channel regulator activity 13/3947 53/18639 0.245283018867925 1.15830508960711 0.324319202177045 0.791893639536262 GO:0016251 RNA polymerase II general transcription initiation factor activity 13/3947 53/18639 0.245283018867925 1.15830508960711 0.324319202177045 0.791893639536262 GO:0016878 acid-thiol ligase activity 8/3947 31/18639 0.258064516129032 1.21866341933849 0.327795653047911 0.791893639536262 GO:0061134 peptidase regulator activity 51/3947 226/18639 0.225663716814159 1.06565645241933 0.328102057606745 0.791893639536262 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 5/3947 18/18639 0.277777777777778 1.31175576387129 0.328787698421029 0.791893639536262 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 5/3947 18/18639 0.277777777777778 1.31175576387129 0.328787698421029 0.791893639536262 GO:0015172 acidic amino acid transmembrane transporter activity 5/3947 18/18639 0.277777777777778 1.31175576387129 0.328787698421029 0.791893639536262 GO:0031690 adrenergic receptor binding 5/3947 18/18639 0.277777777777778 1.31175576387129 0.328787698421029 0.791893639536262 GO:0032393 MHC class I receptor activity 5/3947 18/18639 0.277777777777778 1.31175576387129 0.328787698421029 0.791893639536262 GO:0035615 clathrin adaptor activity 5/3947 18/18639 0.277777777777778 1.31175576387129 0.328787698421029 0.791893639536262 GO:1990381 ubiquitin-specific protease binding 5/3947 18/18639 0.277777777777778 1.31175576387129 0.328787698421029 0.791893639536262 GO:0051082 unfolded protein binding 28/3947 121/18639 0.231404958677686 1.09276843800187 0.331329430693688 0.794480124160409 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 10/3947 40/18639 0.25 1.18058018748417 0.333751297715881 0.794480124160409 GO:0030331 nuclear estrogen receptor binding 10/3947 40/18639 0.25 1.18058018748417 0.333751297715881 0.794480124160409 GO:0019903 protein phosphatase binding 33/3947 144/18639 0.229166666666667 1.08219850519382 0.334776022880474 0.794480124160409 GO:0008408 3'-5' exonuclease activity 14/3947 58/18639 0.241379310344828 1.13987052584678 0.338094102194115 0.794480124160409 GO:0019208 phosphatase regulator activity 27/3947 117/18639 0.230769230769231 1.08976632690846 0.341135507299473 0.794480124160409 GO:0008320 protein transmembrane transporter activity 7/3947 27/18639 0.259259259259259 1.22430537961321 0.341875563232281 0.794480124160409 GO:0016405 CoA-ligase activity 7/3947 27/18639 0.259259259259259 1.22430537961321 0.341875563232281 0.794480124160409 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 7/3947 27/18639 0.259259259259259 1.22430537961321 0.341875563232281 0.794480124160409 GO:0005161 platelet-derived growth factor receptor binding 4/3947 14/18639 0.285714285714286 1.3492344999819 0.342751380998406 0.794480124160409 GO:0005313 L-glutamate transmembrane transporter activity 4/3947 14/18639 0.285714285714286 1.3492344999819 0.342751380998406 0.794480124160409 GO:0005347 ATP transmembrane transporter activity 4/3947 14/18639 0.285714285714286 1.3492344999819 0.342751380998406 0.794480124160409 GO:0008474 palmitoyl-(protein) hydrolase activity 4/3947 14/18639 0.285714285714286 1.3492344999819 0.342751380998406 0.794480124160409 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 4/3947 14/18639 0.285714285714286 1.3492344999819 0.342751380998406 0.794480124160409 GO:0031404 chloride ion binding 4/3947 14/18639 0.285714285714286 1.3492344999819 0.342751380998406 0.794480124160409 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 4/3947 14/18639 0.285714285714286 1.3492344999819 0.342751380998406 0.794480124160409 GO:0042043 neurexin family protein binding 4/3947 14/18639 0.285714285714286 1.3492344999819 0.342751380998406 0.794480124160409 GO:0042813 Wnt receptor activity 4/3947 14/18639 0.285714285714286 1.3492344999819 0.342751380998406 0.794480124160409 GO:0070742 C2H2 zinc finger domain binding 4/3947 14/18639 0.285714285714286 1.3492344999819 0.342751380998406 0.794480124160409 GO:0098599 palmitoyl hydrolase activity 4/3947 14/18639 0.285714285714286 1.3492344999819 0.342751380998406 0.794480124160409 GO:0098821 BMP receptor activity 4/3947 14/18639 0.285714285714286 1.3492344999819 0.342751380998406 0.794480124160409 GO:0098847 sequence-specific single stranded DNA binding 4/3947 14/18639 0.285714285714286 1.3492344999819 0.342751380998406 0.794480124160409 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 9/3947 36/18639 0.25 1.18058018748417 0.347681390929774 0.8017958607156 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 9/3947 36/18639 0.25 1.18058018748417 0.347681390929774 0.8017958607156 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 9/3947 36/18639 0.25 1.18058018748417 0.347681390929774 0.8017958607156 GO:0050661 NADP binding 13/3947 54/18639 0.240740740740741 1.13685499535512 0.350966279619142 0.802215633460878 GO:0004519 endonuclease activity 29/3947 127/18639 0.228346456692913 1.07832521061546 0.35642602684337 0.802215633460878 GO:0019783 ubiquitin-like protein peptidase activity 29/3947 127/18639 0.228346456692913 1.07832521061546 0.35642602684337 0.802215633460878 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 3/3947 10/18639 0.3 1.416696224981 0.35792069192023 0.802215633460878 GO:0005381 iron ion transmembrane transporter activity 3/3947 10/18639 0.3 1.416696224981 0.35792069192023 0.802215633460878 GO:0005522 profilin binding 3/3947 10/18639 0.3 1.416696224981 0.35792069192023 0.802215633460878 GO:0005528 FK506 binding 3/3947 10/18639 0.3 1.416696224981 0.35792069192023 0.802215633460878 GO:0016783 sulfurtransferase activity 3/3947 10/18639 0.3 1.416696224981 0.35792069192023 0.802215633460878 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 3/3947 10/18639 0.3 1.416696224981 0.35792069192023 0.802215633460878 GO:0031957 very long-chain fatty acid-CoA ligase activity 3/3947 10/18639 0.3 1.416696224981 0.35792069192023 0.802215633460878 GO:0032395 MHC class II receptor activity 3/3947 10/18639 0.3 1.416696224981 0.35792069192023 0.802215633460878 GO:0050815 phosphoserine residue binding 3/3947 10/18639 0.3 1.416696224981 0.35792069192023 0.802215633460878 GO:0070097 delta-catenin binding 3/3947 10/18639 0.3 1.416696224981 0.35792069192023 0.802215633460878 GO:0071723 lipopeptide binding 3/3947 10/18639 0.3 1.416696224981 0.35792069192023 0.802215633460878 GO:0098505 G-rich strand telomeric DNA binding 3/3947 10/18639 0.3 1.416696224981 0.35792069192023 0.802215633460878 GO:0141109 transporter activator activity 3/3947 10/18639 0.3 1.416696224981 0.35792069192023 0.802215633460878 GO:1905394 retromer complex binding 3/3947 10/18639 0.3 1.416696224981 0.35792069192023 0.802215633460878 GO:0008234 cysteine-type peptidase activity 42/3947 187/18639 0.224598930481283 1.06062818982535 0.360635096382815 0.806965661213032 GO:0140223 general transcription initiation factor activity 16/3947 68/18639 0.235294117647059 1.11113429410274 0.362332950895422 0.807528534294995 GO:0070717 poly-purine tract binding 8/3947 32/18639 0.25 1.18058018748417 0.363013185091607 0.807528534294995 GO:1901681 sulfur compound binding 61/3947 275/18639 0.221818181818182 1.04749660271322 0.363495646496557 0.807528534294995 GO:0036002 pre-mRNA binding 14/3947 59/18639 0.23728813559322 1.12055068642565 0.363864258447081 0.807528534294995 GO:0070063 RNA polymerase binding 14/3947 59/18639 0.23728813559322 1.12055068642565 0.363864258447081 0.807528534294995 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 19/3947 82/18639 0.231707317073171 1.09419627132679 0.370411813830308 0.820716371820094 GO:0003756 protein disulfide isomerase activity 5/3947 19/18639 0.263157894736842 1.24271598682544 0.375384331363333 0.826963093915723 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 5/3947 19/18639 0.263157894736842 1.24271598682544 0.375384331363333 0.826963093915723 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 5/3947 19/18639 0.263157894736842 1.24271598682544 0.375384331363333 0.826963093915723 GO:0004536 DNA nuclease activity 15/3947 64/18639 0.234375 1.1067939257664 0.375670550038411 0.826963093915723 GO:0045499 chemorepellent activity 7/3947 28/18639 0.25 1.18058018748417 0.380099198942235 0.834004067581991 GO:0051959 dynein light intermediate chain binding 7/3947 28/18639 0.25 1.18058018748417 0.380099198942235 0.834004067581991 GO:0019199 transmembrane receptor protein kinase activity 18/3947 78/18639 0.230769230769231 1.08976632690846 0.383156573700239 0.839354303614741 GO:0001098 basal transcription machinery binding 14/3947 60/18639 0.233333333333333 1.10187484165189 0.38992064591326 0.851420927308181 GO:0001099 basal RNA polymerase II transcription machinery binding 14/3947 60/18639 0.233333333333333 1.10187484165189 0.38992064591326 0.851420927308181 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 19/3947 83/18639 0.228915662650602 1.08101318372044 0.392559630967322 0.853725246049678 GO:0005021 vascular endothelial growth factor receptor activity 12/3947 51/18639 0.235294117647059 1.11113429410274 0.393180382176048 0.853725246049678 GO:0030544 Hsp70 protein binding 12/3947 51/18639 0.235294117647059 1.11113429410274 0.393180382176048 0.853725246049678 GO:0000774 adenyl-nucleotide exchange factor activity 4/3947 15/18639 0.266666666666667 1.25928553331644 0.396193230523407 0.853725246049678 GO:0005523 tropomyosin binding 4/3947 15/18639 0.266666666666667 1.25928553331644 0.396193230523407 0.853725246049678 GO:0008252 nucleotidase activity 4/3947 15/18639 0.266666666666667 1.25928553331644 0.396193230523407 0.853725246049678 GO:0016846 carbon-sulfur lyase activity 4/3947 15/18639 0.266666666666667 1.25928553331644 0.396193230523407 0.853725246049678 GO:0120283 protein serine/threonine kinase binding 4/3947 15/18639 0.266666666666667 1.25928553331644 0.396193230523407 0.853725246049678 GO:0048029 monosaccharide binding 17/3947 74/18639 0.22972972972973 1.08485746958004 0.396642260332815 0.853725246049678 GO:0140311 protein sequestering activity 8/3947 33/18639 0.242424242424242 1.14480503028768 0.398548767013554 0.854364557421657 GO:0015295 solute:proton symporter activity 6/3947 24/18639 0.25 1.18058018748417 0.399459534959683 0.854364557421657 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 6/3947 24/18639 0.25 1.18058018748417 0.399459534959683 0.854364557421657 GO:0070300 phosphatidic acid binding 6/3947 24/18639 0.25 1.18058018748417 0.399459534959683 0.854364557421657 GO:0120013 lipid transfer activity 15/3947 65/18639 0.230769230769231 1.08976632690846 0.40085999060184 0.856009680718261 GO:0016835 carbon-oxygen lyase activity 18/3947 79/18639 0.227848101265823 1.07597181644126 0.406047120878801 0.864216956136132 GO:0043495 protein-membrane adaptor activity 11/3947 47/18639 0.234042553191489 1.10522400530432 0.409659634160113 0.864216956136132 GO:0005109 frizzled binding 9/3947 38/18639 0.236842105263158 1.11844438814289 0.414142988254283 0.864216956136132 GO:0141003 histone H2AX kinase activity 77/3947 354/18639 0.217514124293785 1.02717146255684 0.415486383274382 0.864216956136132 GO:0015026 coreceptor activity 14/3947 61/18639 0.229508196721311 1.08381131965759 0.416142554027065 0.864216956136132 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 7/3947 29/18639 0.241379310344828 1.13987052584678 0.41844849106669 0.864216956136132 GO:0097472 cyclin-dependent protein kinase activity 7/3947 29/18639 0.241379310344828 1.13987052584678 0.41844849106669 0.864216956136132 GO:0042393 histone binding 54/3947 247/18639 0.218623481781377 1.03241020443959 0.420161790265316 0.864216956136132 GO:0019003 GDP binding 17/3947 75/18639 0.226666666666667 1.07039270331898 0.420308606163315 0.864216956136132 GO:0000099 sulfur amino acid transmembrane transporter activity 3/3947 11/18639 0.272727272727273 1.28790565907363 0.421620237361944 0.864216956136132 GO:0003953 NAD+ nucleosidase activity 3/3947 11/18639 0.272727272727273 1.28790565907363 0.421620237361944 0.864216956136132 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 3/3947 11/18639 0.272727272727273 1.28790565907363 0.421620237361944 0.864216956136132 GO:0005536 D-glucose binding 3/3947 11/18639 0.272727272727273 1.28790565907363 0.421620237361944 0.864216956136132 GO:0008046 axon guidance receptor activity 3/3947 11/18639 0.272727272727273 1.28790565907363 0.421620237361944 0.864216956136132 GO:0010854 adenylate cyclase regulator activity 3/3947 11/18639 0.272727272727273 1.28790565907363 0.421620237361944 0.864216956136132 GO:0015217 ADP transmembrane transporter activity 3/3947 11/18639 0.272727272727273 1.28790565907363 0.421620237361944 0.864216956136132 GO:0016176 superoxide-generating NADPH oxidase activator activity 3/3947 11/18639 0.272727272727273 1.28790565907363 0.421620237361944 0.864216956136132 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 3/3947 11/18639 0.272727272727273 1.28790565907363 0.421620237361944 0.864216956136132 GO:0019107 myristoyltransferase activity 3/3947 11/18639 0.272727272727273 1.28790565907363 0.421620237361944 0.864216956136132 GO:0019215 intermediate filament binding 3/3947 11/18639 0.272727272727273 1.28790565907363 0.421620237361944 0.864216956136132 GO:0032050 clathrin heavy chain binding 3/3947 11/18639 0.272727272727273 1.28790565907363 0.421620237361944 0.864216956136132 GO:0035252 UDP-xylosyltransferase activity 3/3947 11/18639 0.272727272727273 1.28790565907363 0.421620237361944 0.864216956136132 GO:0042285 xylosyltransferase activity 3/3947 11/18639 0.272727272727273 1.28790565907363 0.421620237361944 0.864216956136132 GO:0047676 arachidonate-CoA ligase activity 3/3947 11/18639 0.272727272727273 1.28790565907363 0.421620237361944 0.864216956136132 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 3/3947 11/18639 0.272727272727273 1.28790565907363 0.421620237361944 0.864216956136132 GO:0048185 activin binding 3/3947 11/18639 0.272727272727273 1.28790565907363 0.421620237361944 0.864216956136132 GO:0010851 cyclase regulator activity 5/3947 20/18639 0.25 1.18058018748417 0.421911227848171 0.864216956136132 GO:0003727 single-stranded RNA binding 20/3947 89/18639 0.224719101123595 1.06119567414307 0.423134985737714 0.865416350920573 GO:0004712 protein serine/threonine/tyrosine kinase activity 10/3947 43/18639 0.232558139534884 1.09821412789225 0.427640150464623 0.873313319322332 GO:0000049 tRNA binding 18/3947 80/18639 0.225 1.06252216873575 0.429039696019402 0.874853876394451 GO:0001848 complement binding 6/3947 25/18639 0.24 1.1333569799848 0.441174306883724 0.88710174407745 GO:0003707 nuclear steroid receptor activity 6/3947 25/18639 0.24 1.1333569799848 0.441174306883724 0.88710174407745 GO:0008483 transaminase activity 6/3947 25/18639 0.24 1.1333569799848 0.441174306883724 0.88710174407745 GO:0015662 P-type ion transporter activity 6/3947 25/18639 0.24 1.1333569799848 0.441174306883724 0.88710174407745 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 6/3947 25/18639 0.24 1.1333569799848 0.441174306883724 0.88710174407745 GO:0017056 structural constituent of nuclear pore 6/3947 25/18639 0.24 1.1333569799848 0.441174306883724 0.88710174407745 GO:0042974 nuclear retinoic acid receptor binding 6/3947 25/18639 0.24 1.1333569799848 0.441174306883724 0.88710174407745 GO:0140358 P-type transmembrane transporter activity 6/3947 25/18639 0.24 1.1333569799848 0.441174306883724 0.88710174407745 GO:0015179 L-amino acid transmembrane transporter activity 14/3947 62/18639 0.225806451612903 1.06633049192118 0.442411539861483 0.88710174407745 GO:0015631 tubulin binding 83/3947 385/18639 0.215584415584416 1.01805875907725 0.446711451565435 0.88710174407745 GO:0004707 MAP kinase activity 4/3947 16/18639 0.25 1.18058018748417 0.448852419800451 0.88710174407745 GO:0005324 long-chain fatty acid transmembrane transporter activity 4/3947 16/18639 0.25 1.18058018748417 0.448852419800451 0.88710174407745 GO:0008142 oxysterol binding 4/3947 16/18639 0.25 1.18058018748417 0.448852419800451 0.88710174407745 GO:0008296 3'-5'-DNA exonuclease activity 4/3947 16/18639 0.25 1.18058018748417 0.448852419800451 0.88710174407745 GO:0015562 efflux transmembrane transporter activity 4/3947 16/18639 0.25 1.18058018748417 0.448852419800451 0.88710174407745 GO:0140328 floppase activity 4/3947 16/18639 0.25 1.18058018748417 0.448852419800451 0.88710174407745 GO:0004864 protein phosphatase inhibitor activity 12/3947 53/18639 0.226415094339623 1.06920469809887 0.450180086888306 0.88710174407745 GO:0001618 virus receptor activity 18/3947 81/18639 0.222222222222222 1.04940461109704 0.452055534776931 0.88710174407745 GO:0033192 calmodulin-dependent protein phosphatase activity 18/3947 81/18639 0.222222222222222 1.04940461109704 0.452055534776931 0.88710174407745 GO:0140791 histone H2AXS140 phosphatase activity 18/3947 81/18639 0.222222222222222 1.04940461109704 0.452055534776931 0.88710174407745 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 18/3947 81/18639 0.222222222222222 1.04940461109704 0.452055534776931 0.88710174407745 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 18/3947 81/18639 0.222222222222222 1.04940461109704 0.452055534776931 0.88710174407745 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 18/3947 81/18639 0.222222222222222 1.04940461109704 0.452055534776931 0.88710174407745 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 18/3947 81/18639 0.222222222222222 1.04940461109704 0.452055534776931 0.88710174407745 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 18/3947 81/18639 0.222222222222222 1.04940461109704 0.452055534776931 0.88710174407745 GO:1990439 MAP kinase serine/threonine phosphatase activity 18/3947 81/18639 0.222222222222222 1.04940461109704 0.452055534776931 0.88710174407745 GO:0001968 fibronectin binding 7/3947 30/18639 0.233333333333333 1.10187484165189 0.456564836529639 0.890794127099555 GO:0008106 alcohol dehydrogenase (NADP+) activity 7/3947 30/18639 0.233333333333333 1.10187484165189 0.456564836529639 0.890794127099555 GO:0015215 nucleotide transmembrane transporter activity 7/3947 30/18639 0.233333333333333 1.10187484165189 0.456564836529639 0.890794127099555 GO:0033612 receptor serine/threonine kinase binding 7/3947 30/18639 0.233333333333333 1.10187484165189 0.456564836529639 0.890794127099555 GO:0016790 thiolester hydrolase activity 10/3947 44/18639 0.227272727272727 1.0732547158947 0.459013069289681 0.893001035806036 GO:0043014 alpha-tubulin binding 10/3947 44/18639 0.227272727272727 1.0732547158947 0.459013069289681 0.893001035806036 GO:0017116 single-stranded DNA helicase activity 13/3947 58/18639 0.224137931034483 1.05845120257201 0.459811253525167 0.893272291948605 GO:0072341 modified amino acid binding 20/3947 91/18639 0.21978021978022 1.03787269229377 0.466691982041567 0.902116249023796 GO:0008373 sialyltransferase activity 5/3947 21/18639 0.238095238095238 1.12436208331825 0.467756551154201 0.902116249023796 GO:0070182 DNA polymerase binding 5/3947 21/18639 0.238095238095238 1.12436208331825 0.467756551154201 0.902116249023796 GO:0140312 cargo adaptor activity 5/3947 21/18639 0.238095238095238 1.12436208331825 0.467756551154201 0.902116249023796 GO:0060590 ATPase regulator activity 11/3947 49/18639 0.224489795918367 1.06011282141435 0.469289107073273 0.902116249023796 GO:0033549 MAP kinase phosphatase activity 18/3947 82/18639 0.219512195121951 1.03660699388854 0.475017831293168 0.902116249023796 GO:0140272 exogenous protein binding 18/3947 82/18639 0.219512195121951 1.03660699388854 0.475017831293168 0.902116249023796 GO:1990841 promoter-specific chromatin binding 15/3947 68/18639 0.220588235294118 1.04168840072132 0.476722125538489 0.902116249023796 GO:0003925 G protein activity 12/3947 54/18639 0.222222222222222 1.04940461109704 0.478526888965211 0.902116249023796 GO:0061791 GTPase motor activity 9/3947 40/18639 0.225 1.06252216873575 0.480419782049283 0.902116249023796 GO:1990606 membrane scission GTPase motor activity 9/3947 40/18639 0.225 1.06252216873575 0.480419782049283 0.902116249023796 GO:0051087 protein-folding chaperone binding 29/3947 134/18639 0.216417910447761 1.0219947891654 0.481457241418155 0.902116249023796 GO:0004435 phosphatidylinositol phospholipase C activity 6/3947 26/18639 0.230769230769231 1.08976632690846 0.482277834365825 0.902116249023796 GO:0015216 purine nucleotide transmembrane transporter activity 6/3947 26/18639 0.230769230769231 1.08976632690846 0.482277834365825 0.902116249023796 GO:0019865 immunoglobulin binding 6/3947 26/18639 0.230769230769231 1.08976632690846 0.482277834365825 0.902116249023796 GO:0030507 spectrin binding 6/3947 26/18639 0.230769230769231 1.08976632690846 0.482277834365825 0.902116249023796 GO:0000340 RNA 7-methylguanosine cap binding 3/3947 12/18639 0.25 1.18058018748417 0.482991443061413 0.902116249023796 GO:0004032 aldose reductase (NADPH) activity 3/3947 12/18639 0.25 1.18058018748417 0.482991443061413 0.902116249023796 GO:0005527 macrolide binding 3/3947 12/18639 0.25 1.18058018748417 0.482991443061413 0.902116249023796 GO:0015368 calcium:monoatomic cation antiporter activity 3/3947 12/18639 0.25 1.18058018748417 0.482991443061413 0.902116249023796 GO:0016840 carbon-nitrogen lyase activity 3/3947 12/18639 0.25 1.18058018748417 0.482991443061413 0.902116249023796 GO:0017166 vinculin binding 3/3947 12/18639 0.25 1.18058018748417 0.482991443061413 0.902116249023796 GO:0031543 peptidyl-proline dioxygenase activity 3/3947 12/18639 0.25 1.18058018748417 0.482991443061413 0.902116249023796 GO:0035259 nuclear glucocorticoid receptor binding 3/3947 12/18639 0.25 1.18058018748417 0.482991443061413 0.902116249023796 GO:0045295 gamma-catenin binding 3/3947 12/18639 0.25 1.18058018748417 0.482991443061413 0.902116249023796 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 3/3947 12/18639 0.25 1.18058018748417 0.482991443061413 0.902116249023796 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 3/3947 12/18639 0.25 1.18058018748417 0.482991443061413 0.902116249023796 GO:1990247 N6-methyladenosine-containing RNA reader activity 3/3947 12/18639 0.25 1.18058018748417 0.482991443061413 0.902116249023796 GO:0140101 catalytic activity, acting on a tRNA 30/3947 139/18639 0.215827338129496 1.01920591725252 0.486672034911742 0.906967880408573 GO:0070888 E-box binding 13/3947 59/18639 0.220338983050847 1.04051135168096 0.48692670865593 0.906967880408573 GO:0140303 intramembrane lipid transporter activity 10/3947 45/18639 0.222222222222222 1.04940461109704 0.490102881054839 0.911631696447683 GO:0005310 dicarboxylic acid transmembrane transporter activity 7/3947 31/18639 0.225806451612903 1.06633049192118 0.494122515045143 0.91363953479204 GO:0017147 Wnt-protein binding 7/3947 31/18639 0.225806451612903 1.06633049192118 0.494122515045143 0.91363953479204 GO:0005006 epidermal growth factor receptor activity 11/3947 50/18639 0.22 1.03891056498607 0.498754253698627 0.91363953479204 GO:0015605 organophosphate ester transmembrane transporter activity 11/3947 50/18639 0.22 1.03891056498607 0.498754253698627 0.91363953479204 GO:0004029 aldehyde dehydrogenase (NAD+) activity 4/3947 17/18639 0.235294117647059 1.11113429410274 0.499941397356706 0.91363953479204 GO:0005092 GDP-dissociation inhibitor activity 4/3947 17/18639 0.235294117647059 1.11113429410274 0.499941397356706 0.91363953479204 GO:0008429 phosphatidylethanolamine binding 4/3947 17/18639 0.235294117647059 1.11113429410274 0.499941397356706 0.91363953479204 GO:0016018 cyclosporin A binding 4/3947 17/18639 0.235294117647059 1.11113429410274 0.499941397356706 0.91363953479204 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 4/3947 17/18639 0.235294117647059 1.11113429410274 0.499941397356706 0.91363953479204 GO:0031489 myosin V binding 4/3947 17/18639 0.235294117647059 1.11113429410274 0.499941397356706 0.91363953479204 GO:0032183 SUMO binding 4/3947 17/18639 0.235294117647059 1.11113429410274 0.499941397356706 0.91363953479204 GO:0038191 neuropilin binding 4/3947 17/18639 0.235294117647059 1.11113429410274 0.499941397356706 0.91363953479204 GO:0046965 nuclear retinoid X receptor binding 4/3947 17/18639 0.235294117647059 1.11113429410274 0.499941397356706 0.91363953479204 GO:0042277 peptide binding 53/3947 249/18639 0.21285140562249 1.00515260942427 0.508380545434854 0.92781160108972 GO:0051213 dioxygenase activity 20/3947 93/18639 0.21505376344086 1.01555284944874 0.509928796345985 0.929386354630586 GO:0016881 acid-amino acid ligase activity 5/3947 22/18639 0.227272727272727 1.0732547158947 0.512398185946669 0.929868384901121 GO:0030021 extracellular matrix structural constituent conferring compression resistance 5/3947 22/18639 0.227272727272727 1.0732547158947 0.512398185946669 0.929868384901121 GO:0033691 sialic acid binding 5/3947 22/18639 0.227272727272727 1.0732547158947 0.512398185946669 0.929868384901121 GO:0015175 neutral L-amino acid transmembrane transporter activity 9/3947 41/18639 0.219512195121951 1.03660699388854 0.512936247718317 0.929868384901121 GO:0004714 transmembrane receptor protein tyrosine kinase activity 13/3947 60/18639 0.216666666666667 1.02316949581961 0.513758172818796 0.930114929695978 GO:0017018 myosin phosphatase activity 18/3947 84/18639 0.214285714285714 1.01192587498643 0.520488324863502 0.938231251298879 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 10/3947 46/18639 0.217391304347826 1.02659146737753 0.520736645376791 0.938231251298879 GO:0030276 clathrin binding 10/3947 46/18639 0.217391304347826 1.02659146737753 0.520736645376791 0.938231251298879 GO:0001671 ATPase activator activity 6/3947 27/18639 0.222222222222222 1.04940461109704 0.522392768975408 0.938231251298879 GO:0008266 poly(U) RNA binding 6/3947 27/18639 0.222222222222222 1.04940461109704 0.522392768975408 0.938231251298879 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 6/3947 27/18639 0.222222222222222 1.04940461109704 0.522392768975408 0.938231251298879 GO:0016782 transferase activity, transferring sulphur-containing groups 15/3947 70/18639 0.214285714285714 1.01192587498643 0.526538648877461 0.944426465446875 GO:0005048 signal sequence binding 11/3947 51/18639 0.215686274509804 1.01853976959418 0.527787068367335 0.945415144922201 GO:0044183 protein folding chaperone 16/3947 75/18639 0.213333333333333 1.00742842665315 0.532304078339133 0.947984690288801 GO:0016887 ATP hydrolysis activity 88/3947 417/18639 0.211031175059952 0.996556896869127 0.534425630754783 0.947984690288801 GO:0019905 syntaxin binding 13/3947 61/18639 0.213114754098361 1.00639622539634 0.540195736241557 0.947984690288801 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 102/3947 484/18639 0.210743801652893 0.99519982746599 0.540478769150567 0.947984690288801 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 3/3947 13/18639 0.230769230769231 1.08976632690846 0.5410435231571 0.947984690288801 GO:0004535 poly(A)-specific ribonuclease activity 3/3947 13/18639 0.230769230769231 1.08976632690846 0.5410435231571 0.947984690288801 GO:0017154 semaphorin receptor activity 3/3947 13/18639 0.230769230769231 1.08976632690846 0.5410435231571 0.947984690288801 GO:0031432 titin binding 3/3947 13/18639 0.230769230769231 1.08976632690846 0.5410435231571 0.947984690288801 GO:0031994 insulin-like growth factor I binding 3/3947 13/18639 0.230769230769231 1.08976632690846 0.5410435231571 0.947984690288801 GO:0032396 inhibitory MHC class I receptor activity 3/3947 13/18639 0.230769230769231 1.08976632690846 0.5410435231571 0.947984690288801 GO:0043560 insulin receptor substrate binding 3/3947 13/18639 0.230769230769231 1.08976632690846 0.5410435231571 0.947984690288801 GO:0051011 microtubule minus-end binding 3/3947 13/18639 0.230769230769231 1.08976632690846 0.5410435231571 0.947984690288801 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 3/3947 13/18639 0.230769230769231 1.08976632690846 0.5410435231571 0.947984690288801 GO:0071837 HMG box domain binding 3/3947 13/18639 0.230769230769231 1.08976632690846 0.5410435231571 0.947984690288801 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 3/3947 13/18639 0.230769230769231 1.08976632690846 0.5410435231571 0.947984690288801 GO:0140333 glycerophospholipid flippase activity 3/3947 13/18639 0.230769230769231 1.08976632690846 0.5410435231571 0.947984690288801 GO:0030246 carbohydrate binding 59/3947 280/18639 0.210714285714286 0.995060443736653 0.541106305518829 0.947984690288801 GO:0035403 histone H3T6 kinase activity 52/3947 247/18639 0.210526315789474 0.99417278946035 0.544443895391869 0.948954402415692 GO:0004520 DNA endonuclease activity 9/3947 42/18639 0.214285714285714 1.01192587498643 0.544781227554908 0.948954402415692 GO:0019894 kinesin binding 9/3947 42/18639 0.214285714285714 1.01192587498643 0.544781227554908 0.948954402415692 GO:0051879 Hsp90 protein binding 9/3947 42/18639 0.214285714285714 1.01192587498643 0.544781227554908 0.948954402415692 GO:0000900 mRNA regulatory element binding translation repressor activity 4/3947 18/18639 0.222222222222222 1.04940461109704 0.548842454195472 0.948954402415692 GO:0017128 phospholipid scramblase activity 4/3947 18/18639 0.222222222222222 1.04940461109704 0.548842454195472 0.948954402415692 GO:0050811 GABA receptor binding 4/3947 18/18639 0.222222222222222 1.04940461109704 0.548842454195472 0.948954402415692 GO:0070628 proteasome binding 4/3947 18/18639 0.222222222222222 1.04940461109704 0.548842454195472 0.948954402415692 GO:0098641 cadherin binding involved in cell-cell adhesion 4/3947 18/18639 0.222222222222222 1.04940461109704 0.548842454195472 0.948954402415692 GO:1901611 phosphatidylglycerol binding 4/3947 18/18639 0.222222222222222 1.04940461109704 0.548842454195472 0.948954402415692 GO:0061749 forked DNA-dependent helicase activity 10/3947 47/18639 0.212765957446809 1.0047490957312 0.550757459219137 0.948954402415692 GO:0140938 histone H3 methyltransferase activity 10/3947 47/18639 0.212765957446809 1.0047490957312 0.550757459219137 0.948954402415692 GO:1990518 single-stranded 3'-5' DNA helicase activity 10/3947 47/18639 0.212765957446809 1.0047490957312 0.550757459219137 0.948954402415692 GO:0004602 glutathione peroxidase activity 5/3947 23/18639 0.217391304347826 1.02659146737753 0.555407119814605 0.954084018742317 GO:0070577 lysine-acetylated histone binding 5/3947 23/18639 0.217391304347826 1.02659146737753 0.555407119814605 0.954084018742317 GO:0098631 cell adhesion mediator activity 16/3947 76/18639 0.210526315789474 0.99417278946035 0.555845409149285 0.954084018742317 GO:0001216 DNA-binding transcription activator activity 103/3947 491/18639 0.209775967413442 0.990629403754534 0.561617305299116 0.962555156842663 GO:0035591 signaling adaptor activity 27/3947 129/18639 0.209302325581395 0.988392715103022 0.562200357093945 0.962555156842663 GO:0140767 enzyme-substrate adaptor activity 29/3947 139/18639 0.20863309352518 0.985232386677433 0.569661931083602 0.974100351260232 GO:0001664 G protein-coupled receptor binding 62/3947 297/18639 0.208754208754209 0.985804331636609 0.57397541382479 0.980240127388433 GO:0005518 collagen binding 15/3947 72/18639 0.208333333333333 0.983816822903471 0.574906519529706 0.980595271046894 GO:0009378 four-way junction helicase activity 10/3947 48/18639 0.208333333333333 0.983816822903471 0.580025687577684 0.98244610082151 GO:0036121 double-stranded DNA helicase activity 10/3947 48/18639 0.208333333333333 0.983816822903471 0.580025687577684 0.98244610082151 GO:0043138 3'-5' DNA helicase activity 10/3947 48/18639 0.208333333333333 0.983816822903471 0.580025687577684 0.98244610082151 GO:0000149 SNARE binding 22/3947 106/18639 0.207547169811321 0.980104306590628 0.580729313159259 0.98244610082151 GO:0140097 catalytic activity, acting on DNA 70/3947 336/18639 0.208333333333333 0.983816822903471 0.583385377123367 0.98244610082151 GO:0051018 protein kinase A binding 11/3947 53/18639 0.207547169811321 0.980104306590628 0.584035184297185 0.98244610082151 GO:1901505 carbohydrate derivative transmembrane transporter activity 11/3947 53/18639 0.207547169811321 0.980104306590628 0.584035184297185 0.98244610082151 GO:0005346 purine ribonucleotide transmembrane transporter activity 4/3947 19/18639 0.210526315789474 0.99417278946035 0.595097953617375 0.98244610082151 GO:0005520 insulin-like growth factor binding 4/3947 19/18639 0.210526315789474 0.99417278946035 0.595097953617375 0.98244610082151 GO:0008381 mechanosensitive monoatomic ion channel activity 4/3947 19/18639 0.210526315789474 0.99417278946035 0.595097953617375 0.98244610082151 GO:0008574 plus-end-directed microtubule motor activity 4/3947 19/18639 0.210526315789474 0.99417278946035 0.595097953617375 0.98244610082151 GO:0015245 fatty acid transmembrane transporter activity 4/3947 19/18639 0.210526315789474 0.99417278946035 0.595097953617375 0.98244610082151 GO:0030506 ankyrin binding 4/3947 19/18639 0.210526315789474 0.99417278946035 0.595097953617375 0.98244610082151 GO:0046624 sphingolipid transporter activity 4/3947 19/18639 0.210526315789474 0.99417278946035 0.595097953617375 0.98244610082151 GO:0004705 JUN kinase activity 3/3947 14/18639 0.214285714285714 1.01192587498643 0.595123198291289 0.98244610082151 GO:0008494 translation activator activity 3/3947 14/18639 0.214285714285714 1.01192587498643 0.595123198291289 0.98244610082151 GO:0008559 ABC-type xenobiotic transporter activity 3/3947 14/18639 0.214285714285714 1.01192587498643 0.595123198291289 0.98244610082151 GO:0019992 diacylglycerol binding 3/3947 14/18639 0.214285714285714 1.01192587498643 0.595123198291289 0.98244610082151 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 3/3947 14/18639 0.214285714285714 1.01192587498643 0.595123198291289 0.98244610082151 GO:0032036 myosin heavy chain binding 3/3947 14/18639 0.214285714285714 1.01192587498643 0.595123198291289 0.98244610082151 GO:0046030 inositol trisphosphate phosphatase activity 3/3947 14/18639 0.214285714285714 1.01192587498643 0.595123198291289 0.98244610082151 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 3/3947 14/18639 0.214285714285714 1.01192587498643 0.595123198291289 0.98244610082151 GO:1901612 cardiolipin binding 3/3947 14/18639 0.214285714285714 1.01192587498643 0.595123198291289 0.98244610082151 GO:0030215 semaphorin receptor binding 5/3947 24/18639 0.208333333333333 0.983816822903471 0.596445957934322 0.98244610082151 GO:0140033 acetylation-dependent protein binding 5/3947 24/18639 0.208333333333333 0.983816822903471 0.596445957934322 0.98244610082151 GO:0004629 phospholipase C activity 6/3947 29/18639 0.206896551724138 0.97703187929724 0.598439658046008 0.98244610082151 GO:0016417 S-acyltransferase activity 6/3947 29/18639 0.206896551724138 0.97703187929724 0.598439658046008 0.98244610082151 GO:0043236 laminin binding 6/3947 29/18639 0.206896551724138 0.97703187929724 0.598439658046008 0.98244610082151 GO:0051861 glycolipid binding 6/3947 29/18639 0.206896551724138 0.97703187929724 0.598439658046008 0.98244610082151 GO:0106222 lncRNA binding 6/3947 29/18639 0.206896551724138 0.97703187929724 0.598439658046008 0.98244610082151 GO:0061135 endopeptidase regulator activity 38/3947 184/18639 0.206521739130435 0.975261894008658 0.598451680883899 0.98244610082151 GO:0019888 protein phosphatase regulator activity 22/3947 107/18639 0.205607476635514 0.970944453258005 0.60008787190103 0.98394093627303 GO:0035402 histone H3T11 kinase activity 51/3947 247/18639 0.206477732793522 0.975054081970728 0.606145818096785 0.984507266798178 GO:0005004 GPI-linked ephrin receptor activity 10/3947 49/18639 0.204081632653061 0.963738928558502 0.608419682578815 0.984507266798178 GO:0005008 hepatocyte growth factor receptor activity 10/3947 49/18639 0.204081632653061 0.963738928558502 0.608419682578815 0.984507266798178 GO:0005009 insulin receptor activity 10/3947 49/18639 0.204081632653061 0.963738928558502 0.608419682578815 0.984507266798178 GO:0005011 macrophage colony-stimulating factor receptor activity 10/3947 49/18639 0.204081632653061 0.963738928558502 0.608419682578815 0.984507266798178 GO:0005018 platelet-derived growth factor alpha-receptor activity 10/3947 49/18639 0.204081632653061 0.963738928558502 0.608419682578815 0.984507266798178 GO:0005020 stem cell factor receptor activity 10/3947 49/18639 0.204081632653061 0.963738928558502 0.608419682578815 0.984507266798178 GO:0008288 boss receptor activity 10/3947 49/18639 0.204081632653061 0.963738928558502 0.608419682578815 0.984507266798178 GO:0036332 placental growth factor receptor activity 10/3947 49/18639 0.204081632653061 0.963738928558502 0.608419682578815 0.984507266798178 GO:0038062 protein tyrosine kinase collagen receptor activity 10/3947 49/18639 0.204081632653061 0.963738928558502 0.608419682578815 0.984507266798178 GO:0060175 brain-derived neurotrophic factor receptor activity 10/3947 49/18639 0.204081632653061 0.963738928558502 0.608419682578815 0.984507266798178 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 50/3947 243/18639 0.205761316872428 0.971670936200959 0.61632972619247 0.991372066246517 GO:0035064 methylated histone binding 15/3947 74/18639 0.202702702702703 0.957227179041215 0.621219900345169 0.991372066246517 GO:0008083 growth factor activity 33/3947 162/18639 0.203703703703704 0.961954226838949 0.630175052733065 0.991372066246517 GO:0008187 poly-pyrimidine tract binding 6/3947 30/18639 0.2 0.944464149987332 0.6339083634251 0.991372066246517 GO:0051721 protein phosphatase 2A binding 6/3947 30/18639 0.2 0.944464149987332 0.6339083634251 0.991372066246517 GO:0042605 peptide antigen binding 9/3947 45/18639 0.2 0.944464149987332 0.634745901319539 0.991372066246517 GO:0019706 protein-cysteine S-palmitoyltransferase activity 5/3947 25/18639 0.2 0.944464149987332 0.635263870696971 0.991372066246517 GO:0019707 protein-cysteine S-acyltransferase activity 5/3947 25/18639 0.2 0.944464149987332 0.635263870696971 0.991372066246517 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 5/3947 25/18639 0.2 0.944464149987332 0.635263870696971 0.991372066246517 GO:0005007 fibroblast growth factor receptor activity 10/3947 50/18639 0.2 0.944464149987332 0.635836039798862 0.991372066246517 GO:0005017 platelet-derived growth factor receptor activity 10/3947 50/18639 0.2 0.944464149987332 0.635836039798862 0.991372066246517 GO:0005019 platelet-derived growth factor beta-receptor activity 10/3947 50/18639 0.2 0.944464149987332 0.635836039798862 0.991372066246517 GO:0001614 purinergic nucleotide receptor activity 4/3947 20/18639 0.2 0.944464149987332 0.638394635059677 0.991372066246517 GO:0015095 magnesium ion transmembrane transporter activity 4/3947 20/18639 0.2 0.944464149987332 0.638394635059677 0.991372066246517 GO:0016502 nucleotide receptor activity 4/3947 20/18639 0.2 0.944464149987332 0.638394635059677 0.991372066246517 GO:0031418 L-ascorbic acid binding 4/3947 20/18639 0.2 0.944464149987332 0.638394635059677 0.991372066246517 GO:0042288 MHC class I protein binding 4/3947 20/18639 0.2 0.944464149987332 0.638394635059677 0.991372066246517 GO:0004676 3-phosphoinositide-dependent protein kinase activity 50/3947 245/18639 0.204081632653061 0.963738928558502 0.641314518132323 0.991372066246517 GO:0004711 ribosomal protein S6 kinase activity 50/3947 245/18639 0.204081632653061 0.963738928558502 0.641314518132323 0.991372066246517 GO:0035175 histone H3S10 kinase activity 50/3947 245/18639 0.204081632653061 0.963738928558502 0.641314518132323 0.991372066246517 GO:0035979 histone H2AXS139 kinase activity 50/3947 245/18639 0.204081632653061 0.963738928558502 0.641314518132323 0.991372066246517 GO:0044022 histone H3S28 kinase activity 50/3947 245/18639 0.204081632653061 0.963738928558502 0.641314518132323 0.991372066246517 GO:0044023 histone H4S1 kinase activity 50/3947 245/18639 0.204081632653061 0.963738928558502 0.641314518132323 0.991372066246517 GO:0044024 histone H2AS1 kinase activity 50/3947 245/18639 0.204081632653061 0.963738928558502 0.641314518132323 0.991372066246517 GO:0044025 histone H2BS14 kinase activity 50/3947 245/18639 0.204081632653061 0.963738928558502 0.641314518132323 0.991372066246517 GO:0072354 histone H3T3 kinase activity 50/3947 245/18639 0.204081632653061 0.963738928558502 0.641314518132323 0.991372066246517 GO:0072371 histone H2AS121 kinase activity 50/3947 245/18639 0.204081632653061 0.963738928558502 0.641314518132323 0.991372066246517 GO:0072518 Rho-dependent protein serine/threonine kinase activity 50/3947 245/18639 0.204081632653061 0.963738928558502 0.641314518132323 0.991372066246517 GO:0140823 histone H2BS36 kinase activity 50/3947 245/18639 0.204081632653061 0.963738928558502 0.641314518132323 0.991372066246517 GO:0140855 histone H3S57 kinase activity 50/3947 245/18639 0.204081632653061 0.963738928558502 0.641314518132323 0.991372066246517 GO:0140995 histone H2A kinase activity 50/3947 245/18639 0.204081632653061 0.963738928558502 0.641314518132323 0.991372066246517 GO:0140997 histone H4 kinase activity 50/3947 245/18639 0.204081632653061 0.963738928558502 0.641314518132323 0.991372066246517 GO:0140998 histone H2B kinase activity 50/3947 245/18639 0.204081632653061 0.963738928558502 0.641314518132323 0.991372066246517 GO:1990244 histone H2AT120 kinase activity 50/3947 245/18639 0.204081632653061 0.963738928558502 0.641314518132323 0.991372066246517 GO:0004467 long-chain fatty acid-CoA ligase activity 3/3947 15/18639 0.2 0.944464149987332 0.64485569023326 0.991372066246517 GO:0017081 chloride channel regulator activity 3/3947 15/18639 0.2 0.944464149987332 0.64485569023326 0.991372066246517 GO:0034483 heparan sulfate sulfotransferase activity 3/3947 15/18639 0.2 0.944464149987332 0.64485569023326 0.991372066246517 GO:0140776 protein-containing complex destabilizing activity 3/3947 15/18639 0.2 0.944464149987332 0.64485569023326 0.991372066246517 GO:0004677 DNA-dependent protein kinase activity 50/3947 246/18639 0.203252032520325 0.959821290637533 0.65353614393453 0.991372066246517 GO:0140857 histone H3T45 kinase activity 50/3947 246/18639 0.203252032520325 0.959821290637533 0.65353614393453 0.991372066246517 GO:0140597 protein carrier chaperone 38/3947 188/18639 0.202127659574468 0.954511640944644 0.655550490710009 0.991372066246517 GO:0004222 metalloendopeptidase activity 22/3947 110/18639 0.2 0.944464149987332 0.655781937282725 0.991372066246517 GO:0005506 iron ion binding 31/3947 154/18639 0.201298701298701 0.950597034078159 0.65627013973244 0.991372066246517 GO:0003680 minor groove of adenine-thymine-rich DNA binding 2/3947 10/18639 0.2 0.944464149987332 0.658721409799492 0.991372066246517 GO:0004090 carbonyl reductase (NADPH) activity 2/3947 10/18639 0.2 0.944464149987332 0.658721409799492 0.991372066246517 GO:0004445 inositol-polyphosphate 5-phosphatase activity 2/3947 10/18639 0.2 0.944464149987332 0.658721409799492 0.991372066246517 GO:0008140 cAMP response element binding protein binding 2/3947 10/18639 0.2 0.944464149987332 0.658721409799492 0.991372066246517 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 2/3947 10/18639 0.2 0.944464149987332 0.658721409799492 0.991372066246517 GO:0008519 ammonium channel activity 2/3947 10/18639 0.2 0.944464149987332 0.658721409799492 0.991372066246517 GO:0015203 polyamine transmembrane transporter activity 2/3947 10/18639 0.2 0.944464149987332 0.658721409799492 0.991372066246517 GO:0015279 store-operated calcium channel activity 2/3947 10/18639 0.2 0.944464149987332 0.658721409799492 0.991372066246517 GO:0015658 branched-chain amino acid transmembrane transporter activity 2/3947 10/18639 0.2 0.944464149987332 0.658721409799492 0.991372066246517 GO:0016427 tRNA (cytidine) methyltransferase activity 2/3947 10/18639 0.2 0.944464149987332 0.658721409799492 0.991372066246517 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 2/3947 10/18639 0.2 0.944464149987332 0.658721409799492 0.991372066246517 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 2/3947 10/18639 0.2 0.944464149987332 0.658721409799492 0.991372066246517 GO:0032356 oxidized DNA binding 2/3947 10/18639 0.2 0.944464149987332 0.658721409799492 0.991372066246517 GO:0035256 G protein-coupled glutamate receptor binding 2/3947 10/18639 0.2 0.944464149987332 0.658721409799492 0.991372066246517 GO:0043208 glycosphingolipid binding 2/3947 10/18639 0.2 0.944464149987332 0.658721409799492 0.991372066246517 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 2/3947 10/18639 0.2 0.944464149987332 0.658721409799492 0.991372066246517 GO:0050308 sugar-phosphatase activity 2/3947 10/18639 0.2 0.944464149987332 0.658721409799492 0.991372066246517 GO:0099122 RNA polymerase II C-terminal domain binding 2/3947 10/18639 0.2 0.944464149987332 0.658721409799492 0.991372066246517 GO:0140135 mechanosensitive monoatomic cation channel activity 2/3947 10/18639 0.2 0.944464149987332 0.658721409799492 0.991372066246517 GO:1990757 ubiquitin ligase activator activity 2/3947 10/18639 0.2 0.944464149987332 0.658721409799492 0.991372066246517 GO:0005010 insulin-like growth factor receptor activity 10/3947 51/18639 0.196078431372549 0.92594524508562 0.662189447465088 0.991999308662712 GO:0005030 neurotrophin receptor activity 10/3947 51/18639 0.196078431372549 0.92594524508562 0.662189447465088 0.991999308662712 GO:0004180 carboxypeptidase activity 9/3947 46/18639 0.195652173913043 0.923932320639781 0.662477882494803 0.991999308662712 GO:0042287 MHC protein binding 8/3947 41/18639 0.195121951219512 0.921428439012031 0.663292412988921 0.991999308662712 GO:0000993 RNA polymerase II complex binding 7/3947 36/18639 0.194444444444444 0.918229034709906 0.664842222766208 0.991999308662712 GO:0004033 aldo-keto reductase (NADPH) activity 7/3947 36/18639 0.194444444444444 0.918229034709906 0.664842222766208 0.991999308662712 GO:0016409 palmitoyltransferase activity 7/3947 36/18639 0.194444444444444 0.918229034709906 0.664842222766208 0.991999308662712 GO:0140034 methylation-dependent protein binding 15/3947 76/18639 0.197368421052632 0.932036990119078 0.664990687001774 0.991999308662712 GO:0047499 calcium-independent phospholipase A2 activity 6/3947 31/18639 0.193548387096774 0.91399756450387 0.667456967036289 0.99349247782789 GO:0072349 modified amino acid transmembrane transporter activity 6/3947 31/18639 0.193548387096774 0.91399756450387 0.667456967036289 0.99349247782789 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 18/3947 91/18639 0.197802197802198 0.934085423064394 0.668301618663286 0.993658985644096 GO:0004896 cytokine receptor activity 19/3947 96/18639 0.197916666666667 0.934625981758297 0.669532083566573 0.994398143829433 GO:0008143 poly(A) binding 5/3947 26/18639 0.192307692307692 0.90813860575705 0.671689117442482 0.994961969403062 GO:0030247 polysaccharide binding 5/3947 26/18639 0.192307692307692 0.90813860575705 0.671689117442482 0.994961969403062 GO:0008013 beta-catenin binding 21/3947 106/18639 0.19811320754717 0.935554110836508 0.672112952782599 0.994961969403062 GO:0004679 AMP-activated protein kinase activity 50/3947 248/18639 0.201612903225806 0.952080796358198 0.677389508860536 0.999030088426836 GO:0005248 voltage-gated sodium channel activity 4/3947 21/18639 0.19047619047619 0.899489666654602 0.678544772449201 0.999030088426836 GO:0009975 cyclase activity 4/3947 21/18639 0.19047619047619 0.899489666654602 0.678544772449201 0.999030088426836 GO:0010314 phosphatidylinositol-5-phosphate binding 4/3947 21/18639 0.19047619047619 0.899489666654602 0.678544772449201 0.999030088426836 GO:0061891 calcium ion sensor activity 4/3947 21/18639 0.19047619047619 0.899489666654602 0.678544772449201 0.999030088426836 GO:0016500 protein-hormone receptor activity 13/3947 67/18639 0.194029850746269 0.916271190286218 0.685592554950811 1 GO:0015932 nucleobase-containing compound transmembrane transporter activity 11/3947 57/18639 0.192982456140351 0.911325057005321 0.686423055470137 1 GO:0005504 fatty acid binding 9/3947 47/18639 0.191489361702128 0.904274186158084 0.688937982744303 1 GO:0000062 fatty-acyl-CoA binding 3/3947 16/18639 0.1875 0.885435140613124 0.690087214179293 1 GO:0019841 retinol binding 3/3947 16/18639 0.1875 0.885435140613124 0.690087214179293 1 GO:0022858 alanine transmembrane transporter activity 3/3947 16/18639 0.1875 0.885435140613124 0.690087214179293 1 GO:0034450 ubiquitin-ubiquitin ligase activity 3/3947 16/18639 0.1875 0.885435140613124 0.690087214179293 1 GO:0140327 flippase activity 3/3947 16/18639 0.1875 0.885435140613124 0.690087214179293 1 GO:0043175 RNA polymerase core enzyme binding 8/3947 42/18639 0.19047619047619 0.899489666654602 0.691177397796925 1 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 24/3947 122/18639 0.19672131147541 0.928981131135081 0.692589153348899 1 GO:0043394 proteoglycan binding 7/3947 37/18639 0.189189189189189 0.893412033771801 0.694391888634254 1 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 6/3947 32/18639 0.1875 0.885435140613124 0.698985545406479 1 GO:0047498 calcium-dependent phospholipase A2 activity 6/3947 32/18639 0.1875 0.885435140613124 0.698985545406479 1 GO:0030165 PDZ domain binding 16/3947 83/18639 0.192771084337349 0.910326891554055 0.705629710026106 1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 2/3947 11/18639 0.181818181818182 0.858603772715756 0.711410559230058 1 GO:0004016 adenylate cyclase activity 2/3947 11/18639 0.181818181818182 0.858603772715756 0.711410559230058 1 GO:0004523 RNA-DNA hybrid ribonuclease activity 2/3947 11/18639 0.181818181818182 0.858603772715756 0.711410559230058 1 GO:0008271 secondary active sulfate transmembrane transporter activity 2/3947 11/18639 0.181818181818182 0.858603772715756 0.711410559230058 1 GO:0008503 benzodiazepine receptor activity 2/3947 11/18639 0.181818181818182 0.858603772715756 0.711410559230058 1 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 2/3947 11/18639 0.181818181818182 0.858603772715756 0.711410559230058 1 GO:0019203 carbohydrate phosphatase activity 2/3947 11/18639 0.181818181818182 0.858603772715756 0.711410559230058 1 GO:0034056 estrogen response element binding 2/3947 11/18639 0.181818181818182 0.858603772715756 0.711410559230058 1 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 2/3947 11/18639 0.181818181818182 0.858603772715756 0.711410559230058 1 GO:0070697 activin receptor binding 2/3947 11/18639 0.181818181818182 0.858603772715756 0.711410559230058 1 GO:0180030 inositol phosphate kinase activity 2/3947 11/18639 0.181818181818182 0.858603772715756 0.711410559230058 1 GO:0005003 ephrin receptor activity 10/3947 53/18639 0.188679245283019 0.891003915082389 0.711453351520727 1 GO:0005005 transmembrane-ephrin receptor activity 10/3947 53/18639 0.188679245283019 0.891003915082389 0.711453351520727 1 GO:0008146 sulfotransferase activity 10/3947 53/18639 0.188679245283019 0.891003915082389 0.711453351520727 1 GO:0038064 collagen receptor activity 10/3947 53/18639 0.188679245283019 0.891003915082389 0.711453351520727 1 GO:0005516 calmodulin binding 41/3947 207/18639 0.198067632850242 0.935338892499532 0.712036546774809 1 GO:0032266 phosphatidylinositol-3-phosphate binding 9/3947 48/18639 0.1875 0.885435140613124 0.714071589321215 1 GO:0015377 chloride:monoatomic cation symporter activity 4/3947 22/18639 0.181818181818182 0.858603772715756 0.715466236116429 1 GO:0140035 ubiquitin-like protein reader activity 4/3947 22/18639 0.181818181818182 0.858603772715756 0.715466236116429 1 GO:0140784 metal ion sensor activity 4/3947 22/18639 0.181818181818182 0.858603772715756 0.715466236116429 1 GO:0008017 microtubule binding 55/3947 276/18639 0.199275362318841 0.941042178429407 0.717838719908441 1 GO:0042162 telomeric DNA binding 7/3947 38/18639 0.184210526315789 0.869901190777806 0.722190697009731 1 GO:0004620 phospholipase activity 21/3947 109/18639 0.192660550458716 0.909804915125412 0.723238704564199 1 GO:0003678 DNA helicase activity 14/3947 74/18639 0.189189189189189 0.893412033771801 0.726147578678632 1 GO:0019239 deaminase activity 6/3947 33/18639 0.181818181818182 0.858603772715756 0.728438300486847 1 GO:0030296 protein tyrosine kinase activator activity 6/3947 33/18639 0.181818181818182 0.858603772715756 0.728438300486847 1 GO:0017110 nucleoside diphosphate phosphatase activity 3/3947 17/18639 0.176470588235294 0.833350720577058 0.730832746355561 1 GO:0036041 long-chain fatty acid binding 3/3947 17/18639 0.176470588235294 0.833350720577058 0.730832746355561 1 GO:0045125 bioactive lipid receptor activity 3/3947 17/18639 0.176470588235294 0.833350720577058 0.730832746355561 1 GO:1901567 fatty acid derivative binding 3/3947 17/18639 0.176470588235294 0.833350720577058 0.730832746355561 1 GO:0050698 proteoglycan sulfotransferase activity 5/3947 28/18639 0.178571428571429 0.84327156248869 0.73701575778986 1 GO:0101005 deubiquitinase activity 22/3947 115/18639 0.191304347826087 0.903400491292231 0.738979628356936 1 GO:0001046 core promoter sequence-specific DNA binding 8/3947 44/18639 0.181818181818182 0.858603772715756 0.742381753312404 1 GO:0030547 signaling receptor inhibitor activity 8/3947 44/18639 0.181818181818182 0.858603772715756 0.742381753312404 1 GO:0000295 adenine nucleotide transmembrane transporter activity 4/3947 23/18639 0.173913043478261 0.821273173902028 0.749162892179972 1 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 4/3947 23/18639 0.173913043478261 0.821273173902028 0.749162892179972 1 GO:0005283 amino acid:sodium symporter activity 4/3947 23/18639 0.173913043478261 0.821273173902028 0.749162892179972 1 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 11/3947 60/18639 0.183333333333333 0.865758804155054 0.752316049040022 1 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 6/3947 34/18639 0.176470588235294 0.833350720577058 0.755797972400224 1 GO:0090482 vitamin transmembrane transporter activity 6/3947 34/18639 0.176470588235294 0.833350720577058 0.755797972400224 1 GO:0098632 cell-cell adhesion mediator activity 10/3947 55/18639 0.181818181818182 0.858603772715756 0.755865093273846 1 GO:0004000 adenosine deaminase activity 2/3947 12/18639 0.166666666666667 0.787053458322777 0.757094382463788 1 GO:0004126 cytidine deaminase activity 2/3947 12/18639 0.166666666666667 0.787053458322777 0.757094382463788 1 GO:0008179 adenylate cyclase binding 2/3947 12/18639 0.166666666666667 0.787053458322777 0.757094382463788 1 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 2/3947 12/18639 0.166666666666667 0.787053458322777 0.757094382463788 1 GO:0015132 prostaglandin transmembrane transporter activity 2/3947 12/18639 0.166666666666667 0.787053458322777 0.757094382463788 1 GO:0015166 polyol transmembrane transporter activity 2/3947 12/18639 0.166666666666667 0.787053458322777 0.757094382463788 1 GO:0035251 UDP-glucosyltransferase activity 2/3947 12/18639 0.166666666666667 0.787053458322777 0.757094382463788 1 GO:0097677 STAT family protein binding 2/3947 12/18639 0.166666666666667 0.787053458322777 0.757094382463788 1 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 2/3947 12/18639 0.166666666666667 0.787053458322777 0.757094382463788 1 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 2/3947 12/18639 0.166666666666667 0.787053458322777 0.757094382463788 1 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 2/3947 12/18639 0.166666666666667 0.787053458322777 0.757094382463788 1 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 2/3947 12/18639 0.166666666666667 0.787053458322777 0.757094382463788 1 GO:0017022 myosin binding 14/3947 76/18639 0.184210526315789 0.869901190777806 0.763223048426183 1 GO:0004181 metallocarboxypeptidase activity 5/3947 29/18639 0.172413793103448 0.8141932327477 0.765885778569829 1 GO:0005416 amino acid:monoatomic cation symporter activity 5/3947 29/18639 0.172413793103448 0.8141932327477 0.765885778569829 1 GO:0035250 UDP-galactosyltransferase activity 5/3947 29/18639 0.172413793103448 0.8141932327477 0.765885778569829 1 GO:0020037 heme binding 27/3947 142/18639 0.190140845070423 0.897906058086548 0.766370005513085 1 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 3/3947 18/18639 0.166666666666667 0.787053458322777 0.767230804787579 1 GO:0017075 syntaxin-1 binding 3/3947 18/18639 0.166666666666667 0.787053458322777 0.767230804787579 1 GO:0005539 glycosaminoglycan binding 47/3947 242/18639 0.194214876033058 0.917144939037285 0.771893125725247 1 GO:0050997 quaternary ammonium group binding 7/3947 40/18639 0.175 0.826406131238916 0.772445367140304 1 GO:0052689 carboxylic ester hydrolase activity 17/3947 92/18639 0.184782608695652 0.872602747270905 0.774085803469123 1 GO:0005315 phosphate transmembrane transporter activity 4/3947 24/18639 0.166666666666667 0.787053458322777 0.779706279029102 1 GO:0004623 phospholipase A2 activity 6/3947 35/18639 0.171428571428571 0.809540699989142 0.781080156062168 1 GO:0016229 steroid dehydrogenase activity 6/3947 35/18639 0.171428571428571 0.809540699989142 0.781080156062168 1 GO:0042379 chemokine receptor binding 13/3947 72/18639 0.180555555555556 0.852641246516342 0.783297820935806 1 GO:0043177 organic acid binding 36/3947 189/18639 0.19047619047619 0.899489666654602 0.789153462002308 1 GO:0048019 receptor antagonist activity 5/3947 30/18639 0.166666666666667 0.787053458322777 0.792281261598775 1 GO:0002161 aminoacyl-tRNA editing activity 2/3947 13/18639 0.153846153846154 0.72651088460564 0.796376356883185 1 GO:0008035 high-density lipoprotein particle binding 2/3947 13/18639 0.153846153846154 0.72651088460564 0.796376356883185 1 GO:0009982 pseudouridine synthase activity 2/3947 13/18639 0.153846153846154 0.72651088460564 0.796376356883185 1 GO:0046974 histone H3K9 methyltransferase activity 2/3947 13/18639 0.153846153846154 0.72651088460564 0.796376356883185 1 GO:0061459 L-arginine transmembrane transporter activity 2/3947 13/18639 0.153846153846154 0.72651088460564 0.796376356883185 1 GO:0071714 icosanoid transmembrane transporter activity 2/3947 13/18639 0.153846153846154 0.72651088460564 0.796376356883185 1 GO:0089720 caspase binding 2/3947 13/18639 0.153846153846154 0.72651088460564 0.796376356883185 1 GO:0140666 annealing activity 2/3947 13/18639 0.153846153846154 0.72651088460564 0.796376356883185 1 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 2/3947 13/18639 0.153846153846154 0.72651088460564 0.796376356883185 1 GO:0140852 histone ubiquitin ligase activity 2/3947 13/18639 0.153846153846154 0.72651088460564 0.796376356883185 1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 3/3947 19/18639 0.157894736842105 0.745629592095262 0.799505714381992 1 GO:0016918 retinal binding 3/3947 19/18639 0.157894736842105 0.745629592095262 0.799505714381992 1 GO:0022840 leak channel activity 3/3947 19/18639 0.157894736842105 0.745629592095262 0.799505714381992 1 GO:0022842 narrow pore channel activity 3/3947 19/18639 0.157894736842105 0.745629592095262 0.799505714381992 1 GO:0042800 histone H3K4 methyltransferase activity 3/3947 19/18639 0.157894736842105 0.745629592095262 0.799505714381992 1 GO:0042834 peptidoglycan binding 3/3947 19/18639 0.157894736842105 0.745629592095262 0.799505714381992 1 GO:0043395 heparan sulfate proteoglycan binding 3/3947 19/18639 0.157894736842105 0.745629592095262 0.799505714381992 1 GO:0046527 glucosyltransferase activity 3/3947 19/18639 0.157894736842105 0.745629592095262 0.799505714381992 1 GO:0120227 acyl-CoA binding 3/3947 19/18639 0.157894736842105 0.745629592095262 0.799505714381992 1 GO:0140036 ubiquitin-modified protein reader activity 3/3947 19/18639 0.157894736842105 0.745629592095262 0.799505714381992 1 GO:0004869 cysteine-type endopeptidase inhibitor activity 6/3947 36/18639 0.166666666666667 0.787053458322777 0.804327742721361 1 GO:0000030 mannosyltransferase activity 4/3947 25/18639 0.16 0.755571319989866 0.807219118711412 1 GO:0005537 D-mannose binding 4/3947 25/18639 0.16 0.755571319989866 0.807219118711412 1 GO:0015296 monoatomic anion:monoatomic cation symporter activity 4/3947 25/18639 0.16 0.755571319989866 0.807219118711412 1 GO:0047617 fatty acyl-CoA hydrolase activity 4/3947 25/18639 0.16 0.755571319989866 0.807219118711412 1 GO:0140359 ABC-type transporter activity 8/3947 47/18639 0.170212765957447 0.803799276584964 0.807568095330733 1 GO:1901682 sulfur compound transmembrane transporter activity 11/3947 63/18639 0.174603174603175 0.824532194433385 0.808095479544267 1 GO:0070273 phosphatidylinositol-4-phosphate binding 5/3947 31/18639 0.161290322580645 0.761664637086558 0.816285933630022 1 GO:0031406 carboxylic acid binding 35/3947 187/18639 0.18716577540107 0.883856824854455 0.819854225068489 1 GO:0046906 tetrapyrrole binding 28/3947 152/18639 0.184210526315789 0.869901190777806 0.824415498350715 1 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 3/3947 20/18639 0.15 0.708348112490499 0.827937081321224 1 GO:0052745 inositol phosphate phosphatase activity 3/3947 20/18639 0.15 0.708348112490499 0.827937081321224 1 GO:0008191 metalloendopeptidase inhibitor activity 2/3947 14/18639 0.142857142857143 0.674617249990952 0.829918549981835 1 GO:0008195 phosphatidate phosphatase activity 2/3947 14/18639 0.142857142857143 0.674617249990952 0.829918549981835 1 GO:0015386 potassium:proton antiporter activity 2/3947 14/18639 0.142857142857143 0.674617249990952 0.829918549981835 1 GO:0015926 glucosidase activity 2/3947 14/18639 0.142857142857143 0.674617249990952 0.829918549981835 1 GO:0032454 histone H3K9 demethylase activity 2/3947 14/18639 0.142857142857143 0.674617249990952 0.829918549981835 1 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 2/3947 14/18639 0.142857142857143 0.674617249990952 0.829918549981835 1 GO:1901474 azole transmembrane transporter activity 2/3947 14/18639 0.142857142857143 0.674617249990952 0.829918549981835 1 GO:0005319 lipid transporter activity 33/3947 178/18639 0.185393258426966 0.875486431168033 0.83051263885477 1 GO:0016289 acyl-CoA hydrolase activity 4/3947 26/18639 0.153846153846154 0.72651088460564 0.831860937123945 1 GO:0043548 phosphatidylinositol 3-kinase binding 4/3947 26/18639 0.153846153846154 0.72651088460564 0.831860937123945 1 GO:0120014 phospholipid transfer activity 4/3947 26/18639 0.153846153846154 0.72651088460564 0.831860937123945 1 GO:0005245 voltage-gated calcium channel activity 7/3947 43/18639 0.162790697674419 0.768749889524573 0.834743943797282 1 GO:0008375 acetylglucosaminyltransferase activity 7/3947 43/18639 0.162790697674419 0.768749889524573 0.834743943797282 1 GO:0005200 structural constituent of cytoskeleton 20/3947 112/18639 0.178571428571429 0.84327156248869 0.835939375462538 1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 15/3947 86/18639 0.174418604651163 0.823660595919185 0.83686845805824 1 GO:0008378 galactosyltransferase activity 5/3947 32/18639 0.15625 0.737862617177603 0.838008227745493 1 GO:0008094 ATP-dependent activity, acting on DNA 39/3947 210/18639 0.185714285714286 0.877002424988237 0.844918038760321 1 GO:0000146 microfilament motor activity 6/3947 38/18639 0.157894736842105 0.745629592095262 0.844995953642957 1 GO:0005501 retinoid binding 6/3947 38/18639 0.157894736842105 0.745629592095262 0.844995953642957 1 GO:0019840 isoprenoid binding 6/3947 38/18639 0.157894736842105 0.745629592095262 0.844995953642957 1 GO:0004175 endopeptidase activity 78/3947 405/18639 0.192592592592593 0.909483996284098 0.845339046902767 1 GO:0004843 cysteine-type deubiquitinase activity 19/3947 108/18639 0.175925925925926 0.83077865045182 0.849576038259492 1 GO:0005253 monoatomic anion channel activity 18/3947 103/18639 0.174757281553398 0.825259936882135 0.85213896004442 1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 3/3947 21/18639 0.142857142857143 0.674617249990952 0.852835799466562 1 GO:0015174 basic amino acid transmembrane transporter activity 3/3947 21/18639 0.142857142857143 0.674617249990952 0.852835799466562 1 GO:0019200 carbohydrate kinase activity 3/3947 21/18639 0.142857142857143 0.674617249990952 0.852835799466562 1 GO:0035613 RNA stem-loop binding 3/3947 21/18639 0.142857142857143 0.674617249990952 0.852835799466562 1 GO:0005104 fibroblast growth factor receptor binding 4/3947 27/18639 0.148148148148148 0.69960307406469 0.853815864322813 1 GO:0004865 protein serine/threonine phosphatase inhibitor activity 2/3947 15/18639 0.133333333333333 0.629642766658221 0.858389759173923 1 GO:0004953 icosanoid receptor activity 2/3947 15/18639 0.133333333333333 0.629642766658221 0.858389759173923 1 GO:0010181 FMN binding 2/3947 15/18639 0.133333333333333 0.629642766658221 0.858389759173923 1 GO:0015116 sulfate transmembrane transporter activity 2/3947 15/18639 0.133333333333333 0.629642766658221 0.858389759173923 1 GO:0015929 hexosaminidase activity 2/3947 15/18639 0.133333333333333 0.629642766658221 0.858389759173923 1 GO:0030553 cGMP binding 2/3947 15/18639 0.133333333333333 0.629642766658221 0.858389759173923 1 GO:0033130 acetylcholine receptor binding 2/3947 15/18639 0.133333333333333 0.629642766658221 0.858389759173923 1 GO:0042809 nuclear vitamin D receptor binding 2/3947 15/18639 0.133333333333333 0.629642766658221 0.858389759173923 1 GO:0045504 dynein heavy chain binding 2/3947 15/18639 0.133333333333333 0.629642766658221 0.858389759173923 1 GO:0047372 monoacylglycerol lipase activity 2/3947 15/18639 0.133333333333333 0.629642766658221 0.858389759173923 1 GO:0048531 beta-1,3-galactosyltransferase activity 2/3947 15/18639 0.133333333333333 0.629642766658221 0.858389759173923 1 GO:0051371 muscle alpha-actinin binding 2/3947 15/18639 0.133333333333333 0.629642766658221 0.858389759173923 1 GO:0008201 heparin binding 31/3947 172/18639 0.180232558139535 0.851115949116491 0.867682293344804 1 GO:0046915 transition metal ion transmembrane transporter activity 7/3947 45/18639 0.155555555555556 0.734583227767925 0.868163779947154 1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 4/3947 28/18639 0.142857142857143 0.674617249990952 0.873282548744972 1 GO:0019825 oxygen binding 5/3947 34/18639 0.147058823529412 0.694458933814215 0.875121926492177 1 GO:0015108 chloride transmembrane transporter activity 21/3947 121/18639 0.173553719008264 0.819576328501404 0.875265146305303 1 GO:0015144 carbohydrate transmembrane transporter activity 6/3947 40/18639 0.15 0.708348112490499 0.878501985793608 1 GO:0140662 ATP-dependent protein folding chaperone 6/3947 40/18639 0.15 0.708348112490499 0.878501985793608 1 GO:0005548 phospholipid transporter activity 11/3947 68/18639 0.161764705882353 0.763904827195636 0.879455424159822 1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 2/3947 16/18639 0.125 0.590290093742083 0.882432979887442 1 GO:0015385 sodium:proton antiporter activity 2/3947 16/18639 0.125 0.590290093742083 0.882432979887442 1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 2/3947 16/18639 0.125 0.590290093742083 0.882432979887442 1 GO:0016722 oxidoreductase activity, acting on metal ions 2/3947 16/18639 0.125 0.590290093742083 0.882432979887442 1 GO:0022841 potassium ion leak channel activity 2/3947 16/18639 0.125 0.590290093742083 0.882432979887442 1 GO:0097027 ubiquitin-protein transferase activator activity 2/3947 16/18639 0.125 0.590290093742083 0.882432979887442 1 GO:0031490 chromatin DNA binding 22/3947 128/18639 0.171875 0.811648878895364 0.890398294269999 1 GO:0140566 histone reader activity 5/3947 35/18639 0.142857142857143 0.674617249990952 0.890795554897179 1 GO:0140103 catalytic activity, acting on a glycoprotein 3/3947 23/18639 0.130434782608696 0.615954880426521 0.893330156273127 1 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 3/3947 23/18639 0.130434782608696 0.615954880426521 0.893330156273127 1 GO:0003689 DNA clamp loader activity 28/3947 160/18639 0.175 0.826406131238916 0.894665190711877 1 GO:0015171 amino acid transmembrane transporter activity 17/3947 102/18639 0.166666666666667 0.787053458322777 0.895133168597105 1 GO:0004386 helicase activity 27/3947 155/18639 0.174193548387097 0.822597808053483 0.896244110612104 1 GO:0008569 minus-end-directed microtubule motor activity 2/3947 17/18639 0.117647058823529 0.555567147051372 0.902646344358359 1 GO:0045236 CXCR chemokine receptor binding 2/3947 17/18639 0.117647058823529 0.555567147051372 0.902646344358359 1 GO:0070492 oligosaccharide binding 2/3947 17/18639 0.117647058823529 0.555567147051372 0.902646344358359 1 GO:0001786 phosphatidylserine binding 9/3947 59/18639 0.152542372881356 0.720354012702202 0.903048808392755 1 GO:0015459 potassium channel regulator activity 9/3947 59/18639 0.152542372881356 0.720354012702202 0.903048808392755 1 GO:0045505 dynein intermediate chain binding 5/3947 36/18639 0.138888888888889 0.655877881935647 0.90474197621586 1 GO:0000510 H3-H4 histone complex chaperone activity 26/3947 151/18639 0.172185430463576 0.813114831114922 0.904917912792846 1 GO:0140584 chromatin extrusion motor activity 26/3947 151/18639 0.172185430463576 0.813114831114922 0.904917912792846 1 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 26/3947 151/18639 0.172185430463576 0.813114831114922 0.904917912792846 1 GO:0140849 ATP-dependent H2AZ histone chaperone activity 26/3947 151/18639 0.172185430463576 0.813114831114922 0.904917912792846 1 GO:0001965 G-protein alpha-subunit binding 4/3947 30/18639 0.133333333333333 0.629642766658221 0.905571381261337 1 GO:0031210 phosphatidylcholine binding 4/3947 30/18639 0.133333333333333 0.629642766658221 0.905571381261337 1 GO:0035198 miRNA binding 6/3947 42/18639 0.142857142857143 0.674617249990952 0.90569141350924 1 GO:0016298 lipase activity 22/3947 130/18639 0.169230769230769 0.799161973066204 0.905798596692807 1 GO:0000182 rDNA binding 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0003796 lysozyme activity 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0004382 GDP phosphatase activity 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0004935 adrenergic receptor activity 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0004955 prostaglandin receptor activity 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0005131 growth hormone receptor binding 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0005345 purine nucleobase transmembrane transporter activity 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0015187 glycine transmembrane transporter activity 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0015643 toxic substance binding 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0016868 intramolecular phosphotransferase activity 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0019531 oxalate transmembrane transporter activity 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0019911 structural constituent of myelin sheath 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0030957 Tat protein binding 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0031419 cobalamin binding 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0031956 medium-chain fatty acid-CoA ligase activity 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0032052 bile acid binding 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0035374 chondroitin sulfate binding 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0042166 acetylcholine binding 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0043121 neurotrophin binding 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0045322 unmethylated CpG binding 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0051864 histone H3K36 demethylase activity 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0070739 protein-glutamic acid ligase activity 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0070740 tubulin-glutamic acid ligase activity 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0140999 histone H3K4 trimethyltransferase activity 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:1990763 arrestin family protein binding 1/3947 10/18639 0.1 0.472232074993666 0.907466002993111 1 GO:0004806 triacylglycerol lipase activity 3/3947 24/18639 0.125 0.590290093742083 0.909562138736559 1 GO:0019957 C-C chemokine binding 3/3947 24/18639 0.125 0.590290093742083 0.909562138736559 1 GO:0030552 cAMP binding 3/3947 24/18639 0.125 0.590290093742083 0.909562138736559 1 GO:0050699 WW domain binding 3/3947 24/18639 0.125 0.590290093742083 0.909562138736559 1 GO:0140463 chromatin-protein adaptor activity 8/3947 54/18639 0.148148148148148 0.69960307406469 0.910276215294652 1 GO:0015616 DNA translocase activity 26/3947 152/18639 0.171052631578947 0.807765391436534 0.911522066082602 1 GO:0140674 ATP-dependent histone chaperone activity 26/3947 152/18639 0.171052631578947 0.807765391436534 0.911522066082602 1 GO:0003724 RNA helicase activity 12/3947 77/18639 0.155844155844156 0.73594609089922 0.914625578120236 1 GO:0140658 ATP-dependent chromatin remodeler activity 27/3947 158/18639 0.170886075949367 0.806978862330948 0.916045280333298 1 GO:0022829 wide pore channel activity 5/3947 37/18639 0.135135135135135 0.638151452694143 0.917107027192708 1 GO:0030551 cyclic nucleotide binding 5/3947 37/18639 0.135135135135135 0.638151452694143 0.917107027192708 1 GO:0042805 actinin binding 5/3947 37/18639 0.135135135135135 0.638151452694143 0.917107027192708 1 GO:0003774 cytoskeletal motor activity 26/3947 153/18639 0.169934640522876 0.802485879074204 0.91774981186882 1 GO:0061775 cohesin loader activity 26/3947 153/18639 0.169934640522876 0.802485879074204 0.91774981186882 1 GO:0035254 glutamate receptor binding 7/3947 49/18639 0.142857142857143 0.674617249990952 0.918371393113433 1 GO:0005254 chloride channel activity 13/3947 83/18639 0.156626506024096 0.73964059938767 0.918375188775705 1 GO:0004970 glutamate-gated receptor activity 2/3947 18/18639 0.111111111111111 0.524702305548518 0.919573286804707 1 GO:0005372 water transmembrane transporter activity 2/3947 18/18639 0.111111111111111 0.524702305548518 0.919573286804707 1 GO:0034185 apolipoprotein binding 2/3947 18/18639 0.111111111111111 0.524702305548518 0.919573286804707 1 GO:0140713 histone chaperone activity 28/3947 164/18639 0.170731707317073 0.806249884135527 0.920308462641528 1 GO:1902936 phosphatidylinositol bisphosphate binding 18/3947 111/18639 0.162162162162162 0.765781743232972 0.922879383513692 1 GO:0005251 delayed rectifier potassium channel activity 3/3947 25/18639 0.12 0.566678489992399 0.923518005103624 1 GO:0015271 outward rectifier potassium channel activity 3/3947 25/18639 0.12 0.566678489992399 0.923518005103624 1 GO:0008509 monoatomic anion transmembrane transporter activity 25/3947 149/18639 0.167785234899329 0.792335696298098 0.92539993685706 1 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/3947 11/18639 0.0909090909090909 0.429301886357878 0.927071547369416 1 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/3947 11/18639 0.0909090909090909 0.429301886357878 0.927071547369416 1 GO:0002162 dystroglycan binding 1/3947 11/18639 0.0909090909090909 0.429301886357878 0.927071547369416 1 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/3947 11/18639 0.0909090909090909 0.429301886357878 0.927071547369416 1 GO:0004954 prostanoid receptor activity 1/3947 11/18639 0.0909090909090909 0.429301886357878 0.927071547369416 1 GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity 1/3947 11/18639 0.0909090909090909 0.429301886357878 0.927071547369416 1 GO:0008199 ferric iron binding 1/3947 11/18639 0.0909090909090909 0.429301886357878 0.927071547369416 1 GO:0008526 phosphatidylinositol transfer activity 1/3947 11/18639 0.0909090909090909 0.429301886357878 0.927071547369416 1 GO:0015205 nucleobase transmembrane transporter activity 1/3947 11/18639 0.0909090909090909 0.429301886357878 0.927071547369416 1 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/3947 11/18639 0.0909090909090909 0.429301886357878 0.927071547369416 1 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/3947 11/18639 0.0909090909090909 0.429301886357878 0.927071547369416 1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/3947 11/18639 0.0909090909090909 0.429301886357878 0.927071547369416 1 GO:0043522 leucine zipper domain binding 1/3947 11/18639 0.0909090909090909 0.429301886357878 0.927071547369416 1 GO:0043855 cyclic nucleotide-activated monoatomic ion channel activity 1/3947 11/18639 0.0909090909090909 0.429301886357878 0.927071547369416 1 GO:0050998 nitric-oxide synthase binding 1/3947 11/18639 0.0909090909090909 0.429301886357878 0.927071547369416 1 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/3947 11/18639 0.0909090909090909 0.429301886357878 0.927071547369416 1 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/3947 11/18639 0.0909090909090909 0.429301886357878 0.927071547369416 1 GO:0048020 CCR chemokine receptor binding 7/3947 50/18639 0.14 0.661124904991133 0.927973854565641 1 GO:0005125 cytokine activity 41/3947 234/18639 0.175213675213675 0.827415174134201 0.930124714742859 1 GO:0042910 xenobiotic transmembrane transporter activity 4/3947 32/18639 0.125 0.590290093742083 0.930340373161494 1 GO:0008186 ATP-dependent activity, acting on RNA 12/3947 79/18639 0.151898734177215 0.717314544294176 0.930346316974172 1 GO:0033293 monocarboxylic acid binding 12/3947 79/18639 0.151898734177215 0.717314544294176 0.930346316974172 1 GO:0008194 UDP-glycosyltransferase activity 24/3947 145/18639 0.16551724137931 0.781625503437792 0.932747187636313 1 GO:0003777 microtubule motor activity 10/3947 68/18639 0.147058823529412 0.694458933814215 0.932839409169969 1 GO:0005229 intracellularly calcium-gated chloride channel activity 2/3947 19/18639 0.105263157894737 0.497086394730175 0.93369888356032 1 GO:0022821 solute:potassium antiporter activity 2/3947 19/18639 0.105263157894737 0.497086394730175 0.93369888356032 1 GO:0042577 lipid phosphatase activity 2/3947 19/18639 0.105263157894737 0.497086394730175 0.93369888356032 1 GO:0141147 intracellularly calcium-gated channel activity 2/3947 19/18639 0.105263157894737 0.497086394730175 0.93369888356032 1 GO:0001637 G protein-coupled chemoattractant receptor activity 3/3947 26/18639 0.115384615384615 0.54488316345423 0.935473274840104 1 GO:0004950 chemokine receptor activity 3/3947 26/18639 0.115384615384615 0.54488316345423 0.935473274840104 1 GO:0051139 metal cation:proton antiporter activity 3/3947 26/18639 0.115384615384615 0.54488316345423 0.935473274840104 1 GO:0015297 antiporter activity 22/3947 135/18639 0.162962962962963 0.76956338147116 0.936734616561942 1 GO:0001217 DNA-binding transcription repressor activity 49/3947 278/18639 0.176258992805755 0.832351499089555 0.939978148044437 1 GO:0003720 telomerase activity 1/3947 12/18639 0.0833333333333333 0.393526729161388 0.942524016906292 1 GO:0003995 acyl-CoA dehydrogenase activity 1/3947 12/18639 0.0833333333333333 0.393526729161388 0.942524016906292 1 GO:0004859 phospholipase inhibitor activity 1/3947 12/18639 0.0833333333333333 0.393526729161388 0.942524016906292 1 GO:0005078 MAP-kinase scaffold activity 1/3947 12/18639 0.0833333333333333 0.393526729161388 0.942524016906292 1 GO:0008504 monoamine transmembrane transporter activity 1/3947 12/18639 0.0833333333333333 0.393526729161388 0.942524016906292 1 GO:0008603 cAMP-dependent protein kinase regulator activity 1/3947 12/18639 0.0833333333333333 0.393526729161388 0.942524016906292 1 GO:0035197 siRNA binding 1/3947 12/18639 0.0833333333333333 0.393526729161388 0.942524016906292 1 GO:0042301 phosphate ion binding 1/3947 12/18639 0.0833333333333333 0.393526729161388 0.942524016906292 1 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 1/3947 12/18639 0.0833333333333333 0.393526729161388 0.942524016906292 1 GO:0070008 serine-type exopeptidase activity 1/3947 12/18639 0.0833333333333333 0.393526729161388 0.942524016906292 1 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/3947 12/18639 0.0833333333333333 0.393526729161388 0.942524016906292 1 GO:0140900 chloride:bicarbonate antiporter activity 1/3947 12/18639 0.0833333333333333 0.393526729161388 0.942524016906292 1 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 7/3947 52/18639 0.134615384615385 0.635697024029935 0.94425282506257 1 GO:0061980 regulatory RNA binding 8/3947 58/18639 0.137931034482759 0.65135458619816 0.944544195120136 1 GO:0030414 peptidase inhibitor activity 28/3947 169/18639 0.165680473372781 0.782396337267612 0.944943068648633 1 GO:0001972 retinoic acid binding 2/3947 20/18639 0.1 0.472232074993666 0.945450194920219 1 GO:0004683 calcium/calmodulin-dependent protein kinase activity 3/3947 27/18639 0.111111111111111 0.524702305548518 0.945680451154766 1 GO:0035255 ionotropic glutamate receptor binding 3/3947 27/18639 0.111111111111111 0.524702305548518 0.945680451154766 1 GO:0015020 glucuronosyltransferase activity 4/3947 34/18639 0.117647058823529 0.555567147051372 0.94907776125633 1 GO:0046982 protein heterodimerization activity 66/3947 369/18639 0.178861788617886 0.844642735761029 0.950356695781861 1 GO:0015103 inorganic anion transmembrane transporter activity 27/3947 165/18639 0.163636363636364 0.772743395444181 0.950466851765892 1 GO:0005544 calcium-dependent phospholipid binding 7/3947 53/18639 0.132075471698113 0.623702740557672 0.951094147762475 1 GO:0140828 metal cation:monoatomic cation antiporter activity 5/3947 41/18639 0.121951219512195 0.57589277438252 0.953506521657145 1 GO:0016866 intramolecular transferase activity 3/3947 28/18639 0.107142857142857 0.505962937493214 0.954368199443941 1 GO:0051119 sugar transmembrane transporter activity 3/3947 28/18639 0.107142857142857 0.505962937493214 0.954368199443941 1 GO:0051393 alpha-actinin binding 3/3947 28/18639 0.107142857142857 0.505962937493214 0.954368199443941 1 GO:0141052 histone H3 demethylase activity 3/3947 28/18639 0.107142857142857 0.505962937493214 0.954368199443941 1 GO:0003964 RNA-directed DNA polymerase activity 1/3947 13/18639 0.0769230769230769 0.36325544230282 0.954702988574884 1 GO:0004465 lipoprotein lipase activity 1/3947 13/18639 0.0769230769230769 0.36325544230282 0.954702988574884 1 GO:0030955 potassium ion binding 1/3947 13/18639 0.0769230769230769 0.36325544230282 0.954702988574884 1 GO:0045159 myosin II binding 1/3947 13/18639 0.0769230769230769 0.36325544230282 0.954702988574884 1 GO:0046975 histone H3K36 methyltransferase activity 1/3947 13/18639 0.0769230769230769 0.36325544230282 0.954702988574884 1 GO:0016757 glycosyltransferase activity 46/3947 267/18639 0.172284644194757 0.813583350176354 0.954857240518262 1 GO:0015125 bile acid transmembrane transporter activity 2/3947 21/18639 0.0952380952380952 0.449744833327301 0.955199078652184 1 GO:0036122 BMP binding 2/3947 21/18639 0.0952380952380952 0.449744833327301 0.955199078652184 1 GO:0004866 endopeptidase inhibitor activity 26/3947 161/18639 0.161490683229814 0.762610804337597 0.955703869356219 1 GO:0005343 organic acid:sodium symporter activity 4/3947 35/18639 0.114285714285714 0.539693799992761 0.956598045947833 1 GO:0031492 nucleosomal DNA binding 5/3947 42/18639 0.119047619047619 0.562181041659126 0.959968022758213 1 GO:0050321 tau-protein kinase activity 2/3947 22/18639 0.0909090909090909 0.429301886357878 0.963266413465217 1 GO:0015085 calcium ion transmembrane transporter activity 23/3947 147/18639 0.156462585034014 0.738866511894852 0.963732158856055 1 GO:0004065 arylsulfatase activity 1/3947 14/18639 0.0714285714285714 0.337308624995476 0.96430179154358 1 GO:0008331 high voltage-gated calcium channel activity 1/3947 14/18639 0.0714285714285714 0.337308624995476 0.96430179154358 1 GO:0044548 S100 protein binding 1/3947 14/18639 0.0714285714285714 0.337308624995476 0.96430179154358 1 GO:0061783 peptidoglycan muralytic activity 1/3947 14/18639 0.0714285714285714 0.337308624995476 0.96430179154358 1 GO:1990825 sequence-specific mRNA binding 1/3947 14/18639 0.0714285714285714 0.337308624995476 0.96430179154358 1 GO:0005262 calcium channel activity 20/3947 131/18639 0.152671755725191 0.72096499999033 0.965660972356153 1 GO:0031491 nucleosome binding 10/3947 74/18639 0.135135135135135 0.638151452694143 0.966558910457426 1 GO:0170055 lipid transmembrane transporter activity 7/3947 56/18639 0.125 0.590290093742083 0.967329389591519 1 GO:0050660 flavin adenine dinucleotide binding 12/3947 86/18639 0.13953488372093 0.658928476735348 0.967408386965614 1 GO:0032452 histone demethylase activity 3/3947 30/18639 0.1 0.472232074993666 0.967982653704095 1 GO:0005212 structural constituent of eye lens 2/3947 23/18639 0.0869565217391304 0.410636586951014 0.969927009388273 1 GO:0016493 C-C chemokine receptor activity 2/3947 23/18639 0.0869565217391304 0.410636586951014 0.969927009388273 1 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 45/3947 268/18639 0.167910447761194 0.792926991593842 0.970188645639755 1 GO:0015101 organic cation transmembrane transporter activity 11/3947 81/18639 0.135802469135802 0.641302817892633 0.970566550450342 1 GO:0046943 carboxylic acid transmembrane transporter activity 30/3947 188/18639 0.159574468085106 0.753561821798403 0.971142826468849 1 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/3947 15/18639 0.0666666666666667 0.314821383329111 0.971866936712841 1 GO:0008242 omega peptidase activity 1/3947 15/18639 0.0666666666666667 0.314821383329111 0.971866936712841 1 GO:0015250 water channel activity 1/3947 15/18639 0.0666666666666667 0.314821383329111 0.971866936712841 1 GO:0031005 filamin binding 1/3947 15/18639 0.0666666666666667 0.314821383329111 0.971866936712841 1 GO:0005452 solute:inorganic anion antiporter activity 3/3947 31/18639 0.0967741935483871 0.456998782251935 0.973252346424053 1 GO:0008327 methyl-CpG binding 3/3947 31/18639 0.0967741935483871 0.456998782251935 0.973252346424053 1 GO:0140457 protein demethylase activity 3/3947 31/18639 0.0967741935483871 0.456998782251935 0.973252346424053 1 GO:0005342 organic acid transmembrane transporter activity 30/3947 189/18639 0.158730158730159 0.749574722212168 0.973399839734434 1 GO:0008028 monocarboxylic acid transmembrane transporter activity 9/3947 70/18639 0.128571428571429 0.607155524991856 0.973979228491436 1 GO:0015149 hexose transmembrane transporter activity 2/3947 24/18639 0.0833333333333333 0.393526729161388 0.975414724902066 1 GO:0055056 D-glucose transmembrane transporter activity 2/3947 24/18639 0.0833333333333333 0.393526729161388 0.975414724902066 1 GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity 1/3947 16/18639 0.0625 0.295145046871041 0.977829200501201 1 GO:0055102 lipase inhibitor activity 1/3947 16/18639 0.0625 0.295145046871041 0.977829200501201 1 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/3947 16/18639 0.0625 0.295145046871041 0.977829200501201 1 GO:0071949 FAD binding 4/3947 40/18639 0.1 0.472232074993666 0.981010198482849 1 GO:0008484 sulfuric ester hydrolase activity 1/3947 17/18639 0.0588235294117647 0.277783573525686 0.982528129010129 1 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/3947 17/18639 0.0588235294117647 0.277783573525686 0.982528129010129 1 GO:0030548 acetylcholine receptor regulator activity 1/3947 17/18639 0.0588235294117647 0.277783573525686 0.982528129010129 1 GO:0008066 glutamate receptor activity 2/3947 26/18639 0.0769230769230769 0.36325544230282 0.983632000504184 1 GO:0015145 monosaccharide transmembrane transporter activity 2/3947 26/18639 0.0769230769230769 0.36325544230282 0.983632000504184 1 GO:0008227 G protein-coupled amine receptor activity 4/3947 41/18639 0.0975609756097561 0.460714219506016 0.983983568950492 1 GO:0008525 phosphatidylcholine transporter activity 1/3947 18/18639 0.0555555555555556 0.262351152774259 0.986231355022212 1 GO:0015280 ligand-gated sodium channel activity 1/3947 18/18639 0.0555555555555556 0.262351152774259 0.986231355022212 1 GO:0022851 GABA-gated chloride ion channel activity 1/3947 18/18639 0.0555555555555556 0.262351152774259 0.986231355022212 1 GO:0099602 neurotransmitter receptor regulator activity 1/3947 18/18639 0.0555555555555556 0.262351152774259 0.986231355022212 1 GO:0004890 GABA-A receptor activity 1/3947 19/18639 0.0526315789473684 0.248543197365087 0.989149825658984 1 GO:0031420 alkali metal ion binding 1/3947 19/18639 0.0526315789473684 0.248543197365087 0.989149825658984 1 GO:0034987 immunoglobulin receptor binding 1/3947 19/18639 0.0526315789473684 0.248543197365087 0.989149825658984 1 GO:0005242 inward rectifier potassium channel activity 2/3947 28/18639 0.0714285714285714 0.337308624995476 0.989152734068152 1 GO:0005272 sodium channel activity 5/3947 51/18639 0.0980392156862745 0.46297262254281 0.990350926028066 1 GO:0016597 amino acid binding 5/3947 51/18639 0.0980392156862745 0.46297262254281 0.990350926028066 1 GO:0030280 structural constituent of skin epidermis 3/3947 37/18639 0.0810810810810811 0.382890871616486 0.991191789767698 1 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/3947 20/18639 0.05 0.236116037496833 0.991449806224182 1 GO:0005326 neurotransmitter transmembrane transporter activity 1/3947 20/18639 0.05 0.236116037496833 0.991449806224182 1 GO:0015464 acetylcholine receptor activity 1/3947 20/18639 0.05 0.236116037496833 0.991449806224182 1 GO:0030627 pre-mRNA 5'-splice site binding 1/3947 20/18639 0.05 0.236116037496833 0.991449806224182 1 GO:0008514 organic anion transmembrane transporter activity 42/3947 269/18639 0.156133828996283 0.737314020436207 0.991730276779528 1 GO:0016758 hexosyltransferase activity 29/3947 197/18639 0.147208121827411 0.695163968264788 0.991889068876991 1 GO:0004252 serine-type endopeptidase activity 25/3947 176/18639 0.142045454545455 0.670784197434185 0.993162860091796 1 GO:0005184 neuropeptide hormone activity 2/3947 31/18639 0.0645161290322581 0.304665854834623 0.994191273878352 1 GO:0042562 hormone binding 11/3947 94/18639 0.117021276595745 0.552612002652162 0.994316704385284 1 GO:0005243 gap junction channel activity 1/3947 22/18639 0.0454545454545455 0.214650943178939 0.994690720180762 1 GO:0032451 demethylase activity 3/3947 40/18639 0.075 0.35417405624525 0.995031932085207 1 GO:0071855 neuropeptide receptor binding 3/3947 40/18639 0.075 0.35417405624525 0.995031932085207 1 GO:0015106 bicarbonate transmembrane transporter activity 2/3947 32/18639 0.0625 0.295145046871041 0.995291257732115 1 GO:0160041 neuropeptide activity 2/3947 32/18639 0.0625 0.295145046871041 0.995291257732115 1 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/3947 23/18639 0.0434782608695652 0.205318293475507 0.995816343398602 1 GO:0016917 GABA receptor activity 1/3947 23/18639 0.0434782608695652 0.205318293475507 0.995816343398602 1 GO:0099186 structural constituent of postsynapse 1/3947 23/18639 0.0434782608695652 0.205318293475507 0.995816343398602 1 GO:0022832 voltage-gated channel activity 24/3947 175/18639 0.137142857142857 0.647632559991314 0.995816371881362 1 GO:0015294 solute:monoatomic cation symporter activity 14/3947 116/18639 0.120689655172414 0.56993526292339 0.996264375214748 1 GO:0005216 monoatomic ion channel activity 73/3947 448/18639 0.162946428571429 0.769485300770929 0.996426664742675 1 GO:0008236 serine-type peptidase activity 27/3947 194/18639 0.139175257731959 0.657230207465412 0.996440126611796 1 GO:0017171 serine hydrolase activity 27/3947 198/18639 0.136363636363636 0.643952829536817 0.997645263209156 1 GO:0005227 calcium-activated cation channel activity 1/3947 26/18639 0.0384615384615385 0.18162772115141 0.997953180190767 1 GO:0004190 aspartic-type endopeptidase activity 2/3947 36/18639 0.0555555555555556 0.262351152774259 0.997982053490368 1 GO:0004867 serine-type endopeptidase inhibitor activity 10/3947 95/18639 0.105263157894737 0.497086394730175 0.998000376394576 1 GO:0017046 peptide hormone binding 4/3947 53/18639 0.0754716981132075 0.356401566032956 0.99812418248989 1 GO:0070001 aspartic-type peptidase activity 2/3947 37/18639 0.0540540540540541 0.255260581077657 0.998370068560235 1 GO:0008395 steroid hydroxylase activity 1/3947 27/18639 0.037037037037037 0.174900768516173 0.998387220796099 1 GO:0005244 voltage-gated monoatomic ion channel activity 22/3947 173/18639 0.127167630057803 0.600526338142234 0.998593543314839 1 GO:0099095 ligand-gated monoatomic anion channel activity 3/3947 47/18639 0.0638297872340425 0.301424728719361 0.998739164802665 1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 4/3947 56/18639 0.0714285714285714 0.337308624995476 0.998928547683131 1 GO:0015291 secondary active transmembrane transporter activity 41/3947 287/18639 0.142857142857143 0.674617249990952 0.998960987919826 1 GO:0005261 monoatomic cation channel activity 50/3947 341/18639 0.146627565982405 0.692422397351417 0.999211024141696 1 GO:0022839 monoatomic ion-gated channel activity 1/3947 30/18639 0.0333333333333333 0.157410691664555 0.999211097844841 1 GO:0098918 structural constituent of synapse 1/3947 30/18639 0.0333333333333333 0.157410691664555 0.999211097844841 1 GO:0004812 aminoacyl-tRNA ligase activity 2/3947 41/18639 0.0487804878048781 0.230357109753008 0.999310323303791 1 GO:0016875 ligase activity, forming carbon-oxygen bonds 2/3947 41/18639 0.0487804878048781 0.230357109753008 0.999310323303791 1 GO:0008307 structural constituent of muscle 2/3947 42/18639 0.0476190476190476 0.224872416663651 0.999444505327675 1 GO:0042923 neuropeptide binding 1/3947 33/18639 0.0303030303030303 0.143100628785959 0.99961415326396 1 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 3/3947 53/18639 0.0566037735849057 0.267301174524717 0.999622843685748 1 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/3947 34/18639 0.0294117647058824 0.138891786762843 0.999696005197054 1 GO:0051427 hormone receptor binding 1/3947 34/18639 0.0294117647058824 0.138891786762843 0.999696005197054 1 GO:0022824 transmitter-gated monoatomic ion channel activity 4/3947 63/18639 0.0634920634920635 0.299829888884867 0.999718195053146 1 GO:0022835 transmitter-gated channel activity 4/3947 63/18639 0.0634920634920635 0.299829888884867 0.999718195053146 1 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 21/3947 181/18639 0.116022099447514 0.547893567672209 0.999748099856206 1 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/3947 36/18639 0.0277777777777778 0.131175576387129 0.999811309533128 1 GO:0015293 symporter activity 15/3947 146/18639 0.102739726027397 0.485169940061986 0.999846818161018 1 GO:0015079 potassium ion transmembrane transporter activity 17/3947 160/18639 0.10625 0.50174657968077 0.999863506569901 1 GO:0004497 monooxygenase activity 9/3947 106/18639 0.0849056603773585 0.400951761787075 0.99987695633149 1 GO:0099094 ligand-gated monoatomic cation channel activity 13/3947 136/18639 0.0955882352941176 0.45139830697924 0.999908306467627 1 GO:0098960 postsynaptic neurotransmitter receptor activity 4/3947 69/18639 0.0579710144927536 0.273757724634009 0.999912721315247 1 GO:0003730 mRNA 3'-UTR binding 32/3947 262/18639 0.122137404580153 0.576771999992264 0.999947418573334 1 GO:0030594 neurotransmitter receptor activity 7/3947 97/18639 0.0721649484536082 0.340786033500584 0.999955856465931 1 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 4/3947 73/18639 0.0547945205479452 0.258757301366392 0.999960521445485 1 GO:0022843 voltage-gated monoatomic cation channel activity 13/3947 143/18639 0.0909090909090909 0.429301886357878 0.999968617605332 1 GO:0015276 ligand-gated monoatomic ion channel activity 19/3947 186/18639 0.102150537634409 0.482387603488154 0.999977292006993 1 GO:0022836 gated channel activity 40/3947 318/18639 0.125786163522013 0.594002610054926 0.999977545902147 1 GO:0005267 potassium channel activity 10/3947 124/18639 0.0806451612903226 0.380832318543279 0.999979119731327 1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/3947 46/18639 0.0217391304347826 0.102659146737753 0.999982630327459 1 GO:0022834 ligand-gated channel activity 19/3947 188/18639 0.101063829787234 0.477255820472322 0.999982903411519 1 GO:0015370 solute:sodium symporter activity 4/3947 79/18639 0.0506329113924051 0.239104848098059 0.999988175963298 1 GO:0005249 voltage-gated potassium channel activity 6/3947 98/18639 0.0612244897959184 0.289121678567551 0.999991606902368 1 GO:0015081 sodium ion transmembrane transporter activity 14/3947 164/18639 0.0853658536585366 0.403124942067764 0.999996500803572 1 GO:0005179 hormone activity 9/3947 132/18639 0.0681818181818182 0.321976414768409 0.999998611238645 1 GO:0003823 antigen binding 14/3947 174/18639 0.0804597701149425 0.379956841948927 0.99999930939965 1 GO:0001653 peptide receptor activity 7/3947 128/18639 0.0546875 0.258251916012161 0.999999863835974 1 GO:0046873 metal ion transmembrane transporter activity 54/3947 450/18639 0.12 0.566678489992399 0.99999989836651 1 GO:0008528 G protein-coupled peptide receptor activity 6/3947 122/18639 0.0491803278688525 0.23224528278377 0.999999921279203 1 GO:0030527 structural constituent of chromatin 1/3947 98/18639 0.0102040816326531 0.0481869464279251 0.999999999930394 1 GO:0030371 translation repressor activity 9/3947 329/18639 0.027355623100304 0.129182026594012 1 1 GO:0045182 translation regulator activity 16/3947 356/18639 0.0449438202247191 0.212239134828614 1 1