category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	15/113	205/9376	6.07122814590978	COL3A1/MT-ATP6/MT-ND1/MT-CO2/MT-CO3/CD36/MT-CYB/MT-ND3/COL1A1/MT-ND5/COL1A2/MT-ND2/MT-CO1/MT-ND4/RYR2	8.10831777470935
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	10/113	89/9376	9.32285969971164	SPP1/CD36/LAMA2/COL1A1/FN1/COL1A2/COL6A1/COL6A2/LAMA4/VTN	8.71322406257309
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	16/113	275/9376	4.82754625905068	MT-ATP6/MT-ND1/MT-CO2/MT-CO3/MT-CYB/MT-ND3/C1QA/MT-ND5/MT-ND2/MT-CO1/C1QC/C1QB/MT-ND4/C7/EGR1/RYR2	7.11526805269938
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	10/113	103/9376	8.0556748861586	COL3A1/COL1A1/COL1A2/COL6A1/COL14A1/COL15A1/COL6A2/SLC16A10/COL5A2/ELN	7.95236071827393
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	14/113	233/9376	4.98552926430932	COL3A1/DCN/LAMA2/COL1A1/FN1/COL1A2/COL6A1/ACTB/VCAN/FBLN1/COL6A2/COL5A2/ELN/NEBL	6.80406777408998
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	17/113	362/9376	3.89654329438224	SPP1/LAMA2/COL1A1/FN1/HGF/COL1A2/COL6A1/CSH1/COL6A2/MAGI1/GNG10/GNGT1/PRLR/EFNA5/IGF2/LAMA4/VTN	6.20761195088629
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	7/113	50/9376	11.6162831858407	HBA2/HBA1/HBB/CD36/HGF/CCL2/LRP1	8.31301988209453
NA	NA	hsa04518	Integrin signaling	11/113	154/9376	5.92667509481669	SPP1/LAMA2/COL1A1/FN1/HGF/COL1A2/COL6A1/ACTB/COL6A2/LAMA4/VTN	6.80848918103325
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	10/113	138/9376	6.01256893677055	MT-ATP6/MT-ND1/MT-CO2/MT-CO3/MT-CYB/MT-ND3/MT-ND5/MT-ND2/MT-CO1/MT-ND4	6.55178972473653
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	8/113	88/9376	7.54304102976669	F13A1/SERPINE2/C1QA/C1QC/C1QB/C7/CFD/VTN	6.81096901067153
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	12/113	227/9376	4.38626174418151	MT-ATP6/MT-ND1/MT-CO2/MT-CO3/MT-CYB/MT-ND3/MT-ND5/HGF/FOS/MT-ND2/MT-CO1/MT-ND4	5.70421211885088
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	12/113	235/9376	4.23694219544342	MT-ATP6/MT-ND1/MT-CO2/MT-CO3/MT-CYB/MT-ND3/MT-ND5/PRKG1/MT-ND2/ACTB/MT-CO1/MT-ND4	5.55035866908778
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	11/113	203/9376	4.49609834779197	SPP1/LAMA2/COL1A1/FN1/HGF/COL1A2/COL6A1/ACTB/COL6A2/LAMA4/VTN	5.56192324503975
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	11/113	204/9376	4.47405865000868	DCN/LUM/COL1A1/GPC3/FN1/HGF/COL1A2/ACTB/WNT2/IGF2/VTN	5.54075866939147
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	7/113	103/9376	5.63897242031102	COL3A1/LAMA2/COL1A1/CD14/FN1/COL1A2/LAMA4	5.22852634845855
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	10/113	238/9376	3.48627946753923	F13A1/C1QA/FOS/C1QC/C1QB/NRP1/C7/IL6ST/CFD/CCL2	4.29103318342604
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	12/113	333/9376	2.99003428206968	SPP1/LAMA2/COL1A1/FN1/COL1A2/RBPJ/COL6A1/COL6A2/MAGI1/WNT2/LAMA4/VTN	4.08390317859353
NA	NA	hsa04517	IgSF CAM signaling	11/113	299/9376	3.05253499866813	SLIT2/ACTB/PTPRD/MAGI1/NRP1/CADM3/MPDZ/SLIT3/ROBO1/KIRREL1/LMO7	3.98385960943493
Human Diseases	Infectious disease: parasitic	hsa05143	African trypanosomiasis	4/113	37/9376	8.97010284620904	HBA2/HBA1/HBB/LAMA4	5.36492466368964
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	6/113	101/9376	4.9291159204416	COL3A1/COL1A1/FN1/COL1A2/EGR1/CCL2	4.38477787446684
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	10/113	268/9376	3.09602430326245	MT-ATP6/MT-ND1/MT-CO2/MT-CO3/MT-CYB/MT-ND3/MT-ND5/MT-ND2/MT-CO1/MT-ND4	3.84504323847546
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	6/113	103/9376	4.83340493169516	C1QA/FOS/C1QC/C1QB/CCL3/CCL2	4.32058155852009
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	7/113	149/9376	3.89808160598681	MT-ND1/MT-ND3/MT-ND5/MT-ND2/MT-ND4/GNG10/GNGT1	3.93842438975108
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	12/113	388/9376	2.56618921631238	MT-ATP6/MT-ND1/MT-CO2/MT-CO3/MT-CYB/MT-ND3/MT-ND5/MT-ND2/MT-CO1/MT-ND4/WNT2/LRP1	3.47998673279086
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	5/113	78/9376	5.3188109825278	CD14/C1QA/FOS/C1QC/C1QB	4.23024728522605
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	5/113	87/9376	4.76858915674906	MT-CO2/MT-CO3/MT-CYB/MT-CO1/RYR2	3.90034449084967
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	10/113	308/9376	2.69394322491668	MT-ATP6/MT-ND1/MT-CO2/MT-CO3/MT-CYB/MT-ND3/MT-ND5/MT-ND2/MT-CO1/MT-ND4	3.33862376641991
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	11/113	368/9376	2.48018468641785	MT-ATP6/MT-ND1/MT-CO2/MT-CO3/MT-CYB/MT-ND3/MT-ND5/MT-ND2/ACTB/MT-CO1/MT-ND4	3.19944504764082
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	6/113	130/9376	3.82954390742001	COL3A1/COL1A1/COL1A2/FOS/GNG10/GNGT1	3.58806413290393
NA	NA	hsa04081	Hormone signaling	8/113	219/9376	3.03099365579666	PRKG1/CSH1/SLC40A1/GNG10/SLC16A10/GNGT1/PRLR/IGF2	3.35894617844026
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	5/113	97/9376	4.2769820271873	PRKG1/FOS/GNG10/GNGT1/RYR2	3.58309536485632
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	5/113	99/9376	4.19057834987039	C1QA/C1QC/C1QB/FCGR3A/CFD	3.52478199038607
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	5/113	100/9376	4.14867256637168	CXCL14/IL6ST/CCL3/CCL2/CCL4	3.49619911224237
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	5/113	109/9376	3.80612162052448	SPP1/CD14/FOS/CCL3/CCL4	3.25461172956696
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	6/113	155/9376	3.2118755352555	CD36/CD14/ACTB/FCGR3A/COLEC12/MRC1	3.06680774289842
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	12/113	480/9376	2.07433628318584	MT-ATP6/MT-ND1/MT-CO2/MT-CO3/MT-CYB/MT-ND3/MT-ND5/MT-ND2/MT-CO1/MT-ND4/WNT2/RYR2	2.66877833099326
Organismal Systems	Immune system	hsa04611	Platelet activation	5/113	126/9376	3.29259727489816	COL3A1/COL1A1/PRKG1/COL1A2/ACTB	2.86148323609663
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	4/113	86/9376	3.85923029429924	LAMA2/ACTB/GJA1/RYR2	2.94197876158739
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	6/113	184/9376	2.70565602154675	SLIT2/NRP1/EPHA3/SLIT3/EFNA5/ROBO1	2.58074077365113
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	3/113	52/9376	4.78692988427502	CD36/PLTP/LRP1	3.02438330100536
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	5/113	140/9376	2.96333754740834	SPP1/GNG10/EGR1/GNGT1/RYR2	2.58503278740844
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	8/113	298/9376	2.22747520342104	CXCL14/BMP5/CSH1/IL6ST/CCL3/PRLR/CCL2/CCL4	2.37834469997625
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	6/113	193/9376	2.57948553349535	CXCL14/GNG10/GNGT1/CCL3/CCL2/CCL4	2.44878717921663
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	5/113	143/9376	2.90116962683334	C1QA/C1QC/C1QB/C7/FCGR3A	2.53026784376069
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	5/113	157/9376	2.64246660278451	CD36/C1QA/C1QC/C1QB/LRP1	2.29220520410825
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	5/113	157/9376	2.64246660278451	MT-CO2/MT-CO3/MT-CYB/FOS/MT-CO1	2.29220520410825
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	4/113	138/9376	2.40502757470822	FN1/FOS/ACTB/CCL2	1.83647254393185
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	2/113	42/9376	3.95111672987779	FTL/SLC40A1	2.11702585952949
Organismal Systems	Digestive system	hsa04975	Fat digestion and absorption	2/113	43/9376	3.85923029429924	CD36/PLPP3	2.07549532482606
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	5/113	201/9376	2.06401620217497	IGFBP3/CD14/MAF/PROM1/RUNX1T1	1.68419456427757
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	4/113	144/9376	2.30481809242871	CD14/C1QA/C1QC/C1QB	1.74273898317412
Human Diseases	Substance dependence	hsa05032	Morphine addiction	3/113	91/9376	2.73538850530001	GNG10/GNGT1/PDE3A	1.83728058822883
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	3/113	93/9376	2.67656294604625	RBPJ/FOS/MAF	1.7945939135676
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	3/113	93/9376	2.67656294604625	LAMA2/FN1/LAMA4	1.7945939135676
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	3/113	94/9376	2.64808887215214	FOS/S100A9/CCL2	1.77366991557792
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	3/113	95/9376	2.62021425244527	FOS/CCL3/CCL2	1.75301605020352
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	3/113	99/9376	2.51434700992223	LAMA2/ACTB/RYR2	1.67297037792089
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	5/113	216/9376	1.92068174369059	CD36/CD14/FOS/CCL3/CCL2	1.51195093607355
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	2/113	51/9376	3.25386083636995	PLPP3/ENPP2	1.78252977498415
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	3/113	105/9376	2.37067003792668	LAMA2/ACTB/RYR2	1.55995943931187
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	5/113	227/9376	1.82760906007563	GNG10/GNGT1/CCL3/CCL2/CCL4	1.39412071091843
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	3/113	110/9376	2.26291230893001	DCN/BMP5/PITX2	1.47154117542246
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	4/113	170/9376	1.95231650182197	HGF/ACTB/WNT2/IGF2	1.38394653675729
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	5/113	238/9376	1.74313973376961	HGF/GNG10/GNGT1/EFNA5/IGF2	1.28257394197279
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	3/113	115/9376	2.1645248172374	FOS/GNG10/GNGT1	1.38777082857445
Organismal Systems	Digestive system	hsa04978	Mineral absorption	2/113	61/9376	2.72044102712897	FTL/SLC40A1	1.48888894870615
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	3/113	122/9376	2.04033077034673	IGFBP3/CSH1/FOS	1.27742567169719
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	2/113	65/9376	2.55302927161334	SPP1/KISS1	1.38767314712289
Human Diseases	Cancer: specific types	hsa05221	Acute myeloid leukemia	2/113	68/9376	2.44039562727746	CD14/RUNX1T1	1.31660982383722
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	2/113	70/9376	2.37067003792668	LAMA2/ACTB	1.27130408730661
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	2/113	71/9376	2.33728031908264	FOS/PRLR	1.24923017677327
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	4/113	196/9376	1.6933357413762	FOS/GNG10/IL6ST/GNGT1	1.08342614480793
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	3/113	133/9376	1.87158160888948	FOS/GNG10/GNGT1	1.11808914097532
Metabolism	Metabolism of cofactors and vitamins	hsa00770	Pantothenate and CoA biosynthesis	1/113	21/9376	3.95111672987779	ENPP1	1.49528221391328
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	3/113	137/9376	1.81693689038176	FOS/ACTB/CTSC	1.0638620960742
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	2/113	76/9376	2.18351187703773	CD36/PLTP	1.14416055245137
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	2/113	78/9376	2.12752439301112	FN1/ACTB	1.10440281407494
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	2/113	78/9376	2.12752439301112	FOS/FCGR3A	1.10440281407494
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	3/113	142/9376	1.75296023931198	FOS/ACTB/CCL2	0.998551132424269
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	4/113	212/9376	1.56553681749875	HGF/ACTB/MAGI1/EFNA5	0.919888737503371
Metabolism	Carbohydrate metabolism	hsa00650	Butanoate metabolism	1/113	27/9376	3.07309078990495	HMGCLL1	1.19142484508508
Metabolism	Lipid metabolism	hsa01040	Biosynthesis of unsaturated fatty acids	1/113	27/9376	3.07309078990495	ELOVL2	1.19142484508508
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	3/113	154/9376	1.61636593495001	FOS/ACTB/RYR2	0.851795728133094
Metabolism	Lipid metabolism	hsa00062	Fatty acid elongation	1/113	28/9376	2.96333754740834	ELOVL2	1.14911545033513
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	2/113	89/9376	1.86457193994233	PRKG1/GJA1	0.905122674504773
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	2/113	89/9376	1.86457193994233	GNG10/GNGT1	0.905122674504773
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	3/113	157/9376	1.58547996167071	BMP5/ACTB/WNT2	0.817088282201599
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	5/113	300/9376	1.38289085545723	CD14/HGF/FOS/EFNA5/IGF2	0.744453208360706
Organismal Systems	Sensory system	hsa04744	Phototransduction	1/113	29/9376	2.86115349404944	GNGT1	1.10864907120799
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	3/113	160/9376	1.55575221238938	VCAN/PTPRD/CADM3	0.783103178049117
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	1/113	30/9376	2.76578171091445	FOLR2	1.06987682752766
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	4/113	232/9376	1.43057674702472	TMSB4X/FN1/ACTB/C7	0.733458395444351
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	2/113	93/9376	1.78437529736416	ACTB/LMO7	0.839595756259589
NA	NA	hsa04981	Folate transport and metabolism	1/113	31/9376	2.67656294604625	FOLR2	1.03266649260521
Human Diseases	Immune disease	hsa05310	Asthma	1/113	32/9376	2.5929203539823	PRG2	0.99690015566163
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	3/113	168/9376	1.48166877370417	CSH1/IL6ST/PRLR	0.695776098478589
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	2/113	98/9376	1.6933357413762	PLPP3/FCGR3A	0.762041231641011
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	2/113	99/9376	1.67623133994815	PLPP3/FOS	0.747064571688305
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	3/113	170/9376	1.46423737636648	ACTB/MAGI1/MPDZ	0.674649350322591
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	2/113	100/9376	1.65946902654867	CD36/CD14	0.732256205295956
Metabolism	Carbohydrate metabolism	hsa00500	Starch and sucrose metabolism	1/113	36/9376	2.30481809242871	ENPP1	0.866316946843103
Environmental Information Processing	Signal transduction	hsa04064	NF-kappa B signaling pathway	2/113	105/9376	1.58044669195112	CD14/CCL4	0.660606324696601
Metabolism	Metabolism of cofactors and vitamins	hsa00760	Nicotinate and nicotinamide metabolism	1/113	38/9376	2.18351187703773	ENPP1	0.807395848562444
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	3/113	181/9376	1.37525057448785	CD14/FCGR3A/MRC1	0.563032953681967
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	2/113	109/9376	1.52244864820979	FOS/IL6ST	0.605949323836571
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	2/113	112/9376	1.48166877370417	LAMA2/LAMA4	0.566379151115501
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	2/113	115/9376	1.44301654482493	GNG10/GNGT1	0.527945328758548
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	2/113	115/9376	1.44301654482493	FOS/EGR1	0.527945328758548
Human Diseases	Substance dependence	hsa05034	Alcoholism	3/113	191/9376	1.3032479266089	GNG10/GNGT1/HDAC9	0.467653265627145
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	2/113	116/9376	1.43057674702472	GNG10/GNGT1	0.515374707777616
Organismal Systems	Immune system	hsa04613	Neutrophil extracellular trap formation	3/113	195/9376	1.27651463580667	ACTB/FCGR3A/HDAC9	0.43096248144929
Environmental Information Processing	Signal transduction	hsa04668	TNF signaling pathway	2/113	119/9376	1.39451178701569	FOS/CCL2	0.478351742274798
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	1/113	46/9376	1.80377068103117	FTL	0.603558377466365
NA	NA	hsa04082	Neuroactive ligand signaling	3/113	199/9376	1.25085605016232	GNG10/GNGT1/TAC3	0.395047920548291
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	2/113	122/9376	1.36022051356449	ACTB/SLC16A10	0.442315987006572
Metabolism	Amino acid metabolism	hsa00280	Valine, leucine and isoleucine degradation	1/113	48/9376	1.72861356932153	HMGCLL1	0.558949578451584
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	3/113	205/9376	1.21424562918196	RBPJ/IL6ST/HDAC9	0.34255442533205
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	2/113	128/9376	1.29646017699115	ENPP1/PDE3A	0.372989379389935
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	1/113	51/9376	1.62693041818497	ACTB	0.495825704597563
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	5/113	370/9376	1.12126285577613	CSH1/SPX/PRLR/TAC3/KISS1	0.262852256968096
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	1/113	52/9376	1.59564329475834	HSD17B2	0.475702927984844
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	3/113	214/9376	1.16317922421636	FOS/GNG10/GNGT1	0.266701608493508
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	1/113	55/9376	1.50860820595334	PLPP3	0.41781351264954
Human Diseases	Infectious disease: bacterial	hsa05134	Legionellosis	1/113	56/9376	1.48166877370417	CD14	0.39928553519953
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	1/113	57/9376	1.45567458469182	ELOVL2	0.381115495075191
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	3/113	224/9376	1.11125158027813	FOS/NRP1/EGR1	0.186132075481803
Metabolism	Nucleotide metabolism	hsa00240	Pyrimidine metabolism	1/113	59/9376	1.40632968351582	ENPP1	0.345792473252528
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	1/113	59/9376	1.40632968351582	PRKG1	0.345792473252528
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	2/113	142/9376	1.16864015954132	FOS/FCGR3A	0.223645039260062
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	3/113	226/9376	1.10141749549691	FOS/RYR2/PDE3A	0.170453366038417
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/113	60/9376	1.38289085545723	PRKG1	0.328613126526287
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	2/113	144/9376	1.15240904621436	WNT2/IL6ST	0.203560318305945
Environmental Information Processing	Signal transduction	hsa04330	Notch signaling pathway	1/113	62/9376	1.33828147302312	RBPJ	0.295158278650661
Metabolism	Amino acid metabolism	hsa00310	Lysine degradation	1/113	63/9376	1.31703890995926	PRDM6	0.278860542107804
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	1/113	63/9376	1.31703890995926	PTGDS	0.278860542107804
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	1/113	63/9376	1.31703890995926	WNT2	0.278860542107804
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	2/113	148/9376	1.12126285577613	FOS/WNT2	0.164230526234982
NA	NA	hsa04519	Cadherin signaling	5/113	404/9376	1.026899150092	CDH11/ACTB/GJA1/WNT2/MPDZ	0.0610426861455757
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	2/113	150/9376	1.10631268436578	HGF/WNT2	0.144968290091359
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	1/113	65/9376	1.27651463580667	PLPP3	0.247073214851108
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/113	66/9376	1.25717350496112	HSD17B2	0.231564712410209
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/113	66/9376	1.25717350496112	MAF	0.231564712410209
Organismal Systems	Endocrine system	hsa04924	Renin secretion	1/113	69/9376	1.20251378735411	PDE3A	0.186476157722664
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/113	69/9376	1.20251378735411	FOS	0.186476157722664
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/113	70/9376	1.18533501896334	CD36	0.171899261390103
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	1/113	70/9376	1.18533501896334	HGF	0.171899261390103
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	3/113	248/9376	1.00371110476734	CD14/FOS/ACTB	0.00654169463696872
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	3/113	250/9376	0.995681415929204	DAB2/FOLR2/WWP1	-0.00764399120251549
Human Diseases	Cancer: specific types	hsa05218	Melanoma	1/113	73/9376	1.13662262092375	HGF	0.129426009158045
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	1/113	73/9376	1.13662262092375	HGF	0.129426009158045
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	2/113	166/9376	0.999680136475104	PRKG1/PDE3A	-0.000459238167911665
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/113	75/9376	1.10631268436578	IGFBP3	0.102093929923636
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/113	76/9376	1.09175593851886	ACTB	0.0887050880885162
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	1/113	79/9376	1.050296852246	SYT1	0.0495829045852003
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	2/113	173/9376	0.959230651184204	ACTB/CCL2	-0.0597779673163504
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	1/113	80/9376	1.03716814159292	HGF	0.0368737078798156
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	1/113	82/9376	1.01187135765163	LGMN	0.0119249072355674
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	1/113	83/9376	0.999680136475104	HMGCLL1	-0.000323277012784263
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	1/113	83/9376	0.999680136475104	CCL4	-0.000323277012784263
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	2/113	178/9376	0.932285969971164	WNT2/RSPO2	-0.100737458121527
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/113	85/9376	0.976158250910984	ENPP1	-0.0243873928283291
Organismal Systems	Sensory system	hsa04742	Taste transduction	1/113	86/9376	0.96480757357481	SCN9A	-0.0362109240791365
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	1/113	86/9376	0.96480757357481	RYR2	-0.0362109240791365
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	1/113	87/9376	0.953717831349812	FOS	-0.0479002602860158
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	1/113	90/9376	0.921927236971485	FOS	-0.082196910172255
Organismal Systems	Immune system	hsa04662	B cell receptor signaling pathway	1/113	91/9376	0.911796168433337	FOS	-0.093382655843292
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	1/113	93/9376	0.892187648682082	EGR1	-0.115402401048419
Organismal Systems	Digestive system	hsa04970	Salivary secretion	1/113	93/9376	0.892187648682082	PRKG1	-0.115402401048419
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	2/113	200/9376	0.829734513274336	FOS/ACTB	-0.268821467460727
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	1/113	99/9376	0.838115669974077	FOS	-0.178841234544285
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/113	101/9376	0.8215193200736	WNT2	-0.199179192522555
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/113	102/9376	0.813465209092487	RYR2	-0.209206615056985
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/113	104/9376	0.79782164737917	PLPP3	-0.228988482795561
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	1/113	106/9376	0.782768408749374	FOLR2	-0.248419153147272
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	1/113	109/9376	0.761224324104896	CD36	-0.276938144740226
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/113	116/9376	0.715288373512359	ACTB	-0.340782850713335
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/113	117/9376	0.709174797670373	ACTB	-0.349616528064108
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/113	122/9376	0.680110256782243	CD36	-0.392793697684048
Organismal Systems	Immune system	hsa04660	T cell receptor signaling pathway	1/113	122/9376	0.680110256782243	FOS	-0.392793697684048
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	1/113	133/9376	0.623860536296493	FCGR3A	-0.482522170694977
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	1/113	134/9376	0.61920486065249	PRKG1	-0.490354134201289
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	2/113	250/9376	0.663787610619469	LGMN/CTSC	-0.595103511815507
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/113	136/9376	0.610098906819365	FOS	-0.505867698876881
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	2/113	253/9376	0.65591661128406	CD14/ACTB	-0.612779401054694
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	2/113	254/9376	0.653334262420737	HGF/RYR2	-0.618631133792401
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	1/113	139/9376	0.596931304513911	FOS	-0.528773918938647
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	1/113	142/9376	0.584320079770659	WWP1	-0.551261053904144
Human Diseases	Neurodegenerative disease	hsa05017	Spinocerebellar ataxia	1/113	144/9376	0.576204523107178	RBPJ	-0.566029014128143
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/113	149/9376	0.556868800855259	PLPP3	-0.602204823689575
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/113	154/9376	0.538788644983335	RYR2	-0.637377635091946
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	1/113	155/9376	0.535312589209249	WNT2	-0.644297984549966
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	1/113	157/9376	0.528493320556902	IGFBP3	-0.658028639705052
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	1/113	158/9376	0.525148426122998	CDKN1C	-0.664839939482424
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	1/113	158/9376	0.525148426122998	WNT2	-0.664839939482424
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	1/113	163/9376	0.509039578695912	FOS	-0.698375149746686
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/113	168/9376	0.493889591234724	FTL	-0.731082322198413
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	1/113	180/9376	0.460963618485742	CCL2	-0.806499082114025
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	1/113	187/9376	0.443708295868629	CCL2	-0.848668902707225
Cellular Processes	Cell motility	hsa04814	Motor proteins	1/113	194/9376	0.42769820271873	ACTB	-0.889623729188733
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	1/113	205/9376	0.404748543060652	RBPJ	-0.951739466230835
NA	NA	hsa04382	Cornified envelope formation	1/113	217/9376	0.382366135149464	S100A9	-1.01668394554593
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	1/113	217/9376	0.382366135149464	FOS	-1.01668394554593
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	1/113	323/9376	0.256883750239733	EFNA5	-1.5011040166616
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/113	449/9376	0.184796105406311	PRKG1	-1.95517518636215