ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 70/820 175/18639 0.4 9.09219512195122 7.2122342929443e-49 7.03914066991364e-46 GO:0015078 proton transmembrane transporter activity 46/820 185/18639 0.248648648648649 5.65190507580752 2.73219852049041e-22 1.33331287799932e-19 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 27/820 68/18639 0.397058823529412 9.02534074605452 1.89633624869697e-19 6.16941392909414e-17 GO:0009055 electron transfer activity 34/820 116/18639 0.293103448275862 6.66238435660219 3.00105818188549e-19 7.32258196380059e-17 GO:0022853 active monoatomic ion transmembrane transporter activity 33/820 118/18639 0.279661016949153 6.3568313352625 4.95067069267561e-18 9.6637091921028e-16 GO:0015399 primary active transmembrane transporter activity 33/820 166/18639 0.198795180722892 4.51871143109021 2.40461556827287e-13 3.91150799105721e-11 GO:0003954 NADH dehydrogenase activity 16/820 44/18639 0.363636363636364 8.26563192904656 2.23471920614574e-11 3.11583706456891e-09 GO:0008137 NADH dehydrogenase (ubiquinone) activity 15/820 41/18639 0.365853658536585 8.31603212373587 8.57661883275009e-11 1.04634749759551e-08 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 10/820 18/18639 0.555555555555556 12.6280487804878 8.16808577713813e-10 8.85783524276313e-08 GO:0019843 rRNA binding 17/820 65/18639 0.261538461538462 5.94489681050657 1.88271609658522e-09 1.83753091026718e-07 GO:0004129 cytochrome-c oxidase activity 9/820 15/18639 0.6 13.6382926829268 2.3312263515557e-09 2.06843356283487e-07 GO:0030695 GTPase regulator activity 52/820 489/18639 0.106339468302658 2.41714798743079 3.74720278831876e-09 3.01802223934927e-07 GO:0060589 nucleoside-triphosphatase regulator activity 52/820 490/18639 0.106122448979592 2.41221503235441 4.0199066712644e-09 3.01802223934927e-07 GO:0016675 oxidoreductase activity, acting on a heme group of donors 9/820 16/18639 0.5625 12.7858993902439 5.12021599201362e-09 3.56952200586092e-07 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 15/820 58/18639 0.258620689655172 5.87857443229605 1.99752414621213e-08 1.29972237780203e-06 GO:0005178 integrin binding 25/820 161/18639 0.15527950310559 3.52957885168914 3.84185485924775e-08 2.34353146414113e-06 GO:0016651 oxidoreductase activity, acting on NAD(P)H 18/820 88/18639 0.204545454545455 4.64941796008869 4.20374762280046e-08 2.41344569403132e-06 GO:1990948 ubiquitin ligase inhibitor activity 7/820 11/18639 0.636363636363636 14.4648558758315 8.7907435360906e-08 4.76653649512468e-06 GO:0015252 proton channel activity 10/820 27/18639 0.37037037037037 8.41869918699187 1.09690210293638e-07 5.6346129077153e-06 GO:0005201 extracellular matrix structural constituent 23/820 168/18639 0.136904761904762 3.11191202090592 1.3241851643295e-06 5.96895730153922e-05 GO:0023026 MHC class II protein complex binding 9/820 27/18639 0.333333333333333 7.57682926829268 1.35423961475715e-06 5.96895730153922e-05 GO:0031386 protein tag activity 7/820 15/18639 0.466666666666667 10.6075609756098 1.4677763856244e-06 5.96895730153922e-05 GO:0055105 ubiquitin-protein transferase inhibitor activity 7/820 15/18639 0.466666666666667 10.6075609756098 1.4677763856244e-06 5.96895730153922e-05 GO:0141047 molecular tag activity 7/820 15/18639 0.466666666666667 10.6075609756098 1.4677763856244e-06 5.96895730153922e-05 GO:0045296 cadherin binding 35/820 334/18639 0.104790419161677 2.38193734482255 1.91091542226993e-06 7.4602138085418e-05 GO:0038024 cargo receptor activity 13/820 65/18639 0.2 4.54609756097561 4.13897684131541e-06 0.000155370822966301 GO:0005096 GTPase activator activity 29/820 271/18639 0.107011070110701 2.43241382413824 9.56750261647588e-06 0.000345847501988165 GO:0031625 ubiquitin protein ligase binding 31/820 302/18639 0.102649006622517 2.33326199321596 1.10875577993273e-05 0.000376123554875575 GO:0017124 SH3 domain binding 17/820 115/18639 0.147826086956522 3.36015906680806 1.11758023477374e-05 0.000376123554875575 GO:0022804 active transmembrane transporter activity 41/820 457/18639 0.0897155361050328 2.03927789934354 1.29739156208485e-05 0.000422084721531606 GO:0023023 MHC protein complex binding 9/820 37/18639 0.243243243243243 5.52903757415953 2.41903152121596e-05 0.000761604762808639 GO:0005085 guanyl-nucleotide exchange factor activity 25/820 230/18639 0.108695652173913 2.4707051961824 2.9784222558817e-05 0.000908418788043917 GO:0044389 ubiquitin-like protein ligase binding 31/820 322/18639 0.0962732919254658 2.18833888804727 3.88716766603349e-05 0.0011496592854693 GO:0048027 mRNA 5'-UTR binding 7/820 24/18639 0.291666666666667 6.6297256097561 5.57563761503961e-05 0.00160053597419961 GO:0019864 IgG binding 5/820 11/18639 0.454545454545455 10.3320399113082 6.02607808377808e-05 0.0016804149170764 GO:0044325 transmembrane transporter binding 17/820 136/18639 0.125 2.84131097560976 9.98573401081232e-05 0.00270724344293134 GO:0005044 scavenger receptor activity 7/820 27/18639 0.259259259259259 5.89308943089431 0.000127460407764199 0.00336219886426643 GO:0070700 BMP receptor binding 5/820 13/18639 0.384615384615385 8.74249530956848 0.000155936547401897 0.00400510711221714 GO:0046875 ephrin receptor binding 7/820 28/18639 0.25 5.68262195121951 0.000163539879763387 0.00409269032433501 GO:0019763 immunoglobulin receptor activity 5/820 14/18639 0.357142857142857 8.11803135888502 0.000233802219702916 0.00570477416075115 GO:0001664 G protein-coupled receptor binding 27/820 297/18639 0.0909090909090909 2.06640798226164 0.00030616876785157 0.007288310181052 GO:0043539 protein serine/threonine kinase activator activity 11/820 73/18639 0.150684931506849 3.42514199799532 0.000328214935466628 0.00762708992893879 GO:0019887 protein kinase regulator activity 24/820 255/18639 0.0941176470588235 2.1393400286944 0.000392385122783802 0.00879042897294647 GO:0005080 protein kinase C binding 9/820 52/18639 0.173076923076923 3.93412288930582 0.000396289830747587 0.00879042897294647 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 6/820 24/18639 0.25 5.68262195121951 0.000484713322227354 0.0105128933887533 GO:0030020 extracellular matrix structural constituent conferring tensile strength 8/820 44/18639 0.181818181818182 4.13281596452328 0.000587730870118229 0.0124701158529433 GO:0030169 low-density lipoprotein particle binding 5/820 17/18639 0.294117647058824 6.68543758967001 0.000647276327458149 0.0133313466884621 GO:0050840 extracellular matrix binding 10/820 67/18639 0.149253731343284 3.39261012013105 0.000655640001071904 0.0133313466884621 GO:0055106 ubiquitin-protein transferase regulator activity 7/820 36/18639 0.194444444444444 4.41981707317073 0.000848648212273942 0.0168650340529548 GO:0035615 clathrin adaptor activity 5/820 18/18639 0.277777777777778 6.3140243902439 0.000863987400253834 0.0168650340529548 GO:0019207 kinase regulator activity 25/820 287/18639 0.0871080139372822 1.98000764850854 0.000936340286741202 0.0176318167531625 GO:0001851 complement component C3b binding 4/820 11/18639 0.363636363636364 8.26563192904656 0.000957465458931978 0.0176318167531625 GO:0048407 platelet-derived growth factor binding 4/820 11/18639 0.363636363636364 8.26563192904656 0.000957465458931978 0.0176318167531625 GO:0001540 amyloid-beta binding 11/820 83/18639 0.132530120481928 3.01247428739348 0.00100009245063027 0.0180757450336137 GO:0005539 glycosaminoglycan binding 22/820 242/18639 0.0909090909090909 2.06640798226164 0.00106630273604721 0.0186798190317528 GO:0038187 pattern recognition receptor activity 8/820 48/18639 0.166666666666667 3.78841463414634 0.0010717928952645 0.0186798190317528 GO:0005126 cytokine receptor binding 24/820 275/18639 0.0872727272727273 1.98375166297118 0.00114322371336035 0.0195751990217492 GO:0003779 actin binding 34/820 443/18639 0.0767494356659142 1.74455211143534 0.00122251586128754 0.0205719910451145 GO:0005125 cytokine activity 21/820 234/18639 0.0897435897435897 2.03991557223265 0.00160831222182478 0.0266053004830676 GO:0033612 receptor serine/threonine kinase binding 6/820 30/18639 0.2 4.54609756097561 0.00170742706613353 0.0277741469424387 GO:0001846 opsonin binding 5/820 21/18639 0.238095238095238 5.41202090592334 0.001838863085318 0.0289472640527479 GO:0140312 cargo adaptor activity 5/820 21/18639 0.238095238095238 5.41202090592334 0.001838863085318 0.0289472640527479 GO:0005035 death receptor activity 4/820 13/18639 0.307692307692308 6.99399624765478 0.00193329685656708 0.0294827770626479 GO:0035325 Toll-like receptor binding 4/820 13/18639 0.307692307692308 6.99399624765478 0.00193329685656708 0.0294827770626479 GO:0070325 lipoprotein particle receptor binding 6/820 31/18639 0.193548387096774 4.39944925255704 0.00203952166294271 0.0306242022004936 GO:0071813 lipoprotein particle binding 6/820 32/18639 0.1875 4.26196646341463 0.00241815952946063 0.0352257268769191 GO:0071814 protein-lipid complex binding 6/820 32/18639 0.1875 4.26196646341463 0.00241815952946063 0.0352257268769191 GO:0002020 protease binding 14/820 136/18639 0.102941176470588 2.3399031563845 0.00268934196856271 0.0380405472654667 GO:0019838 growth factor binding 14/820 136/18639 0.102941176470588 2.3399031563845 0.00268934196856271 0.0380405472654667 GO:0031681 G-protein beta-subunit binding 5/820 23/18639 0.217391304347826 4.94141039236479 0.00282700246244696 0.0393398096004797 GO:0001618 virus receptor activity 10/820 81/18639 0.123456790123457 2.80623306233062 0.00286180991970703 0.0393398096004797 GO:0004857 enzyme inhibitor activity 31/820 416/18639 0.0745192307692308 1.69385846622889 0.00307756619232026 0.0415065606033879 GO:0140272 exogenous protein binding 10/820 82/18639 0.121951219512195 2.77201070791196 0.00313390826129169 0.0415065606033879 GO:0140297 DNA-binding transcription factor binding 35/820 488/18639 0.0717213114754098 1.63026039584166 0.00322896023346033 0.0415065606033879 GO:0004715 non-membrane spanning protein tyrosine kinase activity 7/820 45/18639 0.155555555555556 3.53585365853659 0.00327522037713026 0.0415065606033879 GO:0008009 chemokine activity 7/820 45/18639 0.155555555555556 3.53585365853659 0.00327522037713026 0.0415065606033879 GO:0030295 protein kinase activator activity 14/820 139/18639 0.100719424460432 2.28940164941218 0.0032864273546303 0.0415065606033879 GO:0016504 peptidase activator activity 8/820 57/18639 0.140350877192982 3.19024390243902 0.00331712267117239 0.0415065606033879 GO:0005523 tropomyosin binding 4/820 15/18639 0.266666666666667 6.06146341463415 0.00344038588852967 0.0425040079393032 GO:0001848 complement binding 5/820 25/18639 0.2 4.54609756097561 0.00415068042985128 0.0506383012441856 GO:0008081 phosphoric diester hydrolase activity 10/820 87/18639 0.114942528735632 2.61269974768713 0.00481848301470362 0.0580597459549474 GO:0019865 immunoglobulin binding 5/820 26/18639 0.192307692307692 4.37124765478424 0.00495582102342758 0.058275678540546 GO:0050750 low-density lipoprotein particle receptor binding 5/820 26/18639 0.192307692307692 4.37124765478424 0.00495582102342758 0.058275678540546 GO:0043394 proteoglycan binding 6/820 37/18639 0.162162162162162 3.68602504943968 0.00514972757036554 0.0598349298651997 GO:0019209 kinase activator activity 14/820 148/18639 0.0945945945945946 2.15018127883982 0.00575501239524578 0.0660810835030574 GO:0042277 peptide binding 20/820 249/18639 0.0803212851405622 1.82574199235968 0.00713677569289924 0.0809941055380193 GO:0051219 phosphoprotein binding 10/820 93/18639 0.10752688172043 2.4441384736428 0.00769807397197757 0.0856165309319434 GO:0046332 SMAD binding 9/820 79/18639 0.113924050632911 2.5895492435937 0.00774528691397457 0.0856165309319434 GO:0003785 actin monomer binding 5/820 29/18639 0.172413793103448 3.9190496215307 0.00802639266124815 0.0856165309319434 GO:0005031 tumor necrosis factor receptor activity 3/820 10/18639 0.3 6.81914634146341 0.00807041070260122 0.0856165309319434 GO:0031720 haptoglobin binding 3/820 10/18639 0.3 6.81914634146341 0.00807041070260122 0.0856165309319434 GO:1905394 retromer complex binding 3/820 10/18639 0.3 6.81914634146341 0.00807041070260122 0.0856165309319434 GO:0048306 calcium-dependent protein binding 9/820 80/18639 0.1125 2.55717987804878 0.00839637742005291 0.0881168210964693 GO:0042169 SH2 domain binding 6/820 41/18639 0.146341463414634 3.32641284949435 0.00858749547721648 0.0891637828272689 GO:0140375 immune receptor activity 14/820 156/18639 0.0897435897435897 2.03991557223265 0.00903438808490531 0.0922163179909109 GO:0008201 heparin binding 15/820 172/18639 0.0872093023255814 1.98230998298355 0.00907045750730271 0.0922163179909109 GO:0042056 chemoattractant activity 6/820 42/18639 0.142857142857143 3.24721254355401 0.00965506267818825 0.0971478471537292 GO:0140313 molecular sequestering activity 7/820 55/18639 0.127272727272727 2.8929711751663 0.0100384870155827 0.0999751359919259 GO:0010854 adenylate cyclase regulator activity 3/820 11/18639 0.272727272727273 6.19922394678492 0.0107377651689772 0.104800588049217 GO:0140031 phosphorylation-dependent protein binding 3/820 11/18639 0.272727272727273 6.19922394678492 0.0107377651689772 0.104800588049217 GO:0019955 cytokine binding 13/820 144/18639 0.0902777777777778 2.05205792682927 0.0110879696746484 0.106284178572734 GO:0051015 actin filament binding 17/820 209/18639 0.0813397129186603 1.84889135254989 0.0111075678426422 0.106284178572734 GO:0061134 peptidase regulator activity 18/820 226/18639 0.079646017699115 1.81039283401684 0.0112230094181443 0.106346186331154 GO:0004860 protein kinase inhibitor activity 9/820 84/18639 0.107142857142857 2.43540940766551 0.0114234424838982 0.10720461407966 GO:0009931 calcium-dependent protein serine/threonine kinase activity 4/820 21/18639 0.19047619047619 4.32961672473868 0.012234670771128 0.112651308232273 GO:0072542 protein phosphatase activator activity 4/820 21/18639 0.19047619047619 4.32961672473868 0.012234670771128 0.112651308232273 GO:0051020 GTPase binding 23/820 315/18639 0.073015873015873 1.65968641114983 0.0123992649701579 0.113099837484805 GO:0005543 phospholipid binding 33/820 497/18639 0.0663983903420523 1.50926780193355 0.0125785804489408 0.113673097390428 GO:0033218 amide binding 19/820 247/18639 0.0769230769230769 1.7484990619137 0.013206875817953 0.116180522082835 GO:0042605 peptide antigen binding 6/820 45/18639 0.133333333333333 3.03073170731707 0.013420410393438 0.116180522082835 GO:0005518 collagen binding 8/820 72/18639 0.111111111111111 2.52560975609756 0.013538074648647 0.116180522082835 GO:0010853 cyclase activator activity 3/820 12/18639 0.25 5.68262195121951 0.0138548813048231 0.116180522082835 GO:0035497 cAMP response element binding 3/820 12/18639 0.25 5.68262195121951 0.0138548813048231 0.116180522082835 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 3/820 12/18639 0.25 5.68262195121951 0.0138548813048231 0.116180522082835 GO:0097371 MDM2/MDM4 family protein binding 3/820 12/18639 0.25 5.68262195121951 0.0138548813048231 0.116180522082835 GO:0140311 protein sequestering activity 5/820 33/18639 0.151515151515152 3.4440133037694 0.0138882263328296 0.116180522082835 GO:0035091 phosphatidylinositol binding 21/820 284/18639 0.073943661971831 1.68077550669873 0.0143883764566908 0.116180522082835 GO:0008093 cytoskeletal anchor activity 4/820 22/18639 0.181818181818182 4.13281596452328 0.0144435984328029 0.116180522082835 GO:0030021 extracellular matrix structural constituent conferring compression resistance 4/820 22/18639 0.181818181818182 4.13281596452328 0.0144435984328029 0.116180522082835 GO:0061133 endopeptidase activator activity 4/820 22/18639 0.181818181818182 4.13281596452328 0.0144435984328029 0.116180522082835 GO:0140517 protein-RNA adaptor activity 4/820 22/18639 0.181818181818182 4.13281596452328 0.0144435984328029 0.116180522082835 GO:0045309 protein phosphorylated amino acid binding 7/820 59/18639 0.11864406779661 2.69683753617197 0.0145225652603544 0.116180522082835 GO:0030276 clathrin binding 6/820 46/18639 0.130434782608696 2.96484623541888 0.0148755691421469 0.118037036445003 GO:0001784 phosphotyrosine residue binding 6/820 47/18639 0.127659574468085 2.90176440062273 0.0164367104319997 0.129372817593804 GO:0005158 insulin receptor binding 4/820 23/18639 0.173913043478261 3.95312831389183 0.0168891975844568 0.131870854739439 GO:0015026 coreceptor activity 7/820 61/18639 0.114754098360656 2.60841663334666 0.0172317020289231 0.131883752557804 GO:0019210 kinase inhibitor activity 9/820 90/18639 0.1 2.2730487804878 0.0174008079313825 0.131883752557804 GO:0017154 semaphorin receptor activity 3/820 13/18639 0.230769230769231 5.24549718574109 0.0174313566393 0.131883752557804 GO:0031432 titin binding 3/820 13/18639 0.230769230769231 5.24549718574109 0.0174313566393 0.131883752557804 GO:1901681 sulfur compound binding 20/820 275/18639 0.0727272727272727 1.65312638580931 0.0195351931250073 0.142600579369137 GO:0005540 hyaluronic acid binding 4/820 24/18639 0.166666666666667 3.78841463414634 0.0195783582330578 0.142600579369137 GO:0042625 ATPase-coupled ion transmembrane transporter activity 4/820 24/18639 0.166666666666667 3.78841463414634 0.0195783582330578 0.142600579369137 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 4/820 24/18639 0.166666666666667 3.78841463414634 0.0195783582330578 0.142600579369137 GO:0046961 proton-transporting ATPase activity, rotational mechanism 4/820 24/18639 0.166666666666667 3.78841463414634 0.0195783582330578 0.142600579369137 GO:0004713 protein tyrosine kinase activity 12/820 140/18639 0.0857142857142857 1.9483275261324 0.0207718154197746 0.15017253222 GO:0005161 platelet-derived growth factor receptor binding 3/820 14/18639 0.214285714285714 4.87081881533101 0.0214727008014783 0.151864898422049 GO:0005344 oxygen carrier activity 3/820 14/18639 0.214285714285714 4.87081881533101 0.0214727008014783 0.151864898422049 GO:0034236 protein kinase A catalytic subunit binding 3/820 14/18639 0.214285714285714 4.87081881533101 0.0214727008014783 0.151864898422049 GO:0019211 phosphatase activator activity 4/820 25/18639 0.16 3.63687804878049 0.0225169635289067 0.158104722332467 GO:0042826 histone deacetylase binding 11/820 127/18639 0.0866141732283465 1.96878240829652 0.0244298380428327 0.170310870927177 GO:0030247 polysaccharide binding 4/820 26/18639 0.153846153846154 3.49699812382739 0.0257098985299028 0.1736797316507 GO:0005200 structural constituent of cytoskeleton 10/820 112/18639 0.0892857142857143 2.02950783972125 0.0258086706871873 0.1736797316507 GO:0030971 receptor tyrosine kinase binding 8/820 81/18639 0.0987654320987654 2.2449864498645 0.0258656030486172 0.1736797316507 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 3/820 15/18639 0.2 4.54609756097561 0.0259807795297154 0.1736797316507 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 3/820 15/18639 0.2 4.54609756097561 0.0259807795297154 0.1736797316507 GO:0005041 low-density lipoprotein particle receptor activity 3/820 15/18639 0.2 4.54609756097561 0.0259807795297154 0.1736797316507 GO:0031072 heat shock protein binding 11/820 131/18639 0.083969465648855 1.90866691491342 0.0298302678104346 0.198056744101933 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 6/820 54/18639 0.111111111111111 2.52560975609756 0.0305966260668915 0.200074978421441 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 3/820 16/18639 0.1875 4.26196646341463 0.0309542230959401 0.200074978421441 GO:0005324 long-chain fatty acid transmembrane transporter activity 3/820 16/18639 0.1875 4.26196646341463 0.0309542230959401 0.200074978421441 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 3/820 16/18639 0.1875 4.26196646341463 0.0309542230959401 0.200074978421441 GO:0051117 ATPase binding 8/820 84/18639 0.0952380952380952 2.16480836236934 0.0313070024529502 0.201023910487364 GO:0097718 disordered domain specific binding 4/820 28/18639 0.142857142857143 3.24721254355401 0.0328734070554933 0.206145836793729 GO:0001530 lipopolysaccharide binding 5/820 41/18639 0.121951219512195 2.77201070791196 0.0329489860338707 0.206145836793729 GO:0042287 MHC protein binding 5/820 41/18639 0.121951219512195 2.77201070791196 0.0329489860338707 0.206145836793729 GO:0061135 endopeptidase regulator activity 14/820 184/18639 0.0760869565217391 1.72949363732768 0.0329495394875223 0.206145836793729 GO:0016874 ligase activity 13/820 167/18639 0.0778443113772455 1.76943917043961 0.0332395285838134 0.20663554075033 GO:1990782 protein tyrosine kinase binding 10/820 117/18639 0.0854700854700855 1.94277673545966 0.0335535181388698 0.20726730192112 GO:0016209 antioxidant activity 8/820 86/18639 0.0930232558139535 2.11446398184912 0.0353409130873183 0.215245274952992 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 3/820 17/18639 0.176470588235294 4.01126255380201 0.0363888016057825 0.215245274952992 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 3/820 17/18639 0.176470588235294 4.01126255380201 0.0363888016057825 0.215245274952992 GO:0005092 GDP-dissociation inhibitor activity 3/820 17/18639 0.176470588235294 4.01126255380201 0.0363888016057825 0.215245274952992 GO:0008429 phosphatidylethanolamine binding 3/820 17/18639 0.176470588235294 4.01126255380201 0.0363888016057825 0.215245274952992 GO:0015278 intracellularly gated calcium channel activity 3/820 17/18639 0.176470588235294 4.01126255380201 0.0363888016057825 0.215245274952992 GO:0019198 transmembrane receptor protein phosphatase activity 3/820 17/18639 0.176470588235294 4.01126255380201 0.0363888016057825 0.215245274952992 GO:0043236 laminin binding 4/820 29/18639 0.137931034482759 3.13523969722456 0.0368489293585725 0.216653946108234 GO:0004601 peroxidase activity 6/820 57/18639 0.105263157894737 2.39268292682927 0.0385417175993158 0.22445903523225 GO:0042379 chemokine receptor binding 7/820 72/18639 0.0972222222222222 2.20990853658537 0.0386363913104693 0.22445903523225 GO:0008200 ion channel inhibitor activity 5/820 43/18639 0.116279069767442 2.6430799773114 0.0394235188217394 0.227676653077028 GO:0003746 translation elongation factor activity 3/820 18/18639 0.166666666666667 3.78841463414634 0.0422777694798084 0.239901761699378 GO:0030228 lipoprotein particle receptor activity 3/820 18/18639 0.166666666666667 3.78841463414634 0.0422777694798084 0.239901761699378 GO:0070064 proline-rich region binding 3/820 18/18639 0.166666666666667 3.78841463414634 0.0422777694798084 0.239901761699378 GO:0001223 transcription coactivator binding 5/820 44/18639 0.113636363636364 2.58300997782705 0.0429306727230824 0.240806532055911 GO:0016248 channel inhibitor activity 5/820 44/18639 0.113636363636364 2.58300997782705 0.0429306727230824 0.240806532055911 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 6/820 59/18639 0.101694915254237 2.31157503100455 0.0445045516855674 0.246797968438147 GO:0070888 E-box binding 6/820 59/18639 0.101694915254237 2.31157503100455 0.0445045516855674 0.246797968438147 GO:0141110 transporter inhibitor activity 5/820 45/18639 0.111111111111111 2.52560975609756 0.046619455514288 0.257065472214379 GO:0015245 fatty acid transmembrane transporter activity 3/820 19/18639 0.157894736842105 3.5890243902439 0.0486121812747068 0.265058597341418 GO:0043395 heparan sulfate proteoglycan binding 3/820 19/18639 0.157894736842105 3.5890243902439 0.0486121812747068 0.265058597341418 GO:0043425 bHLH transcription factor binding 4/820 32/18639 0.125 2.84131097560976 0.0503613042768955 0.272259034814149 GO:0004180 carboxypeptidase activity 5/820 46/18639 0.108695652173913 2.4707051961824 0.0504906611694272 0.272259034814149 GO:0010851 cyclase regulator activity 3/820 20/18639 0.15 3.40957317073171 0.0553811808656176 0.293818825439821 GO:0016505 peptidase activator activity involved in apoptotic process 3/820 20/18639 0.15 3.40957317073171 0.0553811808656176 0.293818825439821 GO:0019956 chemokine binding 4/820 33/18639 0.121212121212121 2.75521064301552 0.0553920736484908 0.293818825439821 GO:1901981 phosphatidylinositol phosphate binding 13/820 185/18639 0.0702702702702703 1.59727752142386 0.0652919766894938 0.334152832983209 GO:0005154 epidermal growth factor receptor binding 4/820 35/18639 0.114285714285714 2.59777003484321 0.0662318957658889 0.334152832983209 GO:0043015 gamma-tubulin binding 4/820 35/18639 0.114285714285714 2.59777003484321 0.0662318957658889 0.334152832983209 GO:0001221 transcription coregulator binding 9/820 115/18639 0.0782608695652174 1.77890774125133 0.0669648496141904 0.334152832983209 GO:0035401 histone H3Y41 kinase activity 9/820 115/18639 0.0782608695652174 1.77890774125133 0.0669648496141904 0.334152832983209 GO:0140801 histone H2AXY142 kinase activity 9/820 115/18639 0.0782608695652174 1.77890774125133 0.0669648496141904 0.334152832983209 GO:0048020 CCR chemokine receptor binding 5/820 50/18639 0.1 2.2730487804878 0.0678024190521562 0.334152832983209 GO:0005131 growth hormone receptor binding 2/820 10/18639 0.2 4.54609756097561 0.0688163108910093 0.334152832983209 GO:0016175 superoxide-generating NAD(P)H oxidase activity 2/820 10/18639 0.2 4.54609756097561 0.0688163108910093 0.334152832983209 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 2/820 10/18639 0.2 4.54609756097561 0.0688163108910093 0.334152832983209 GO:0032395 MHC class II receptor activity 2/820 10/18639 0.2 4.54609756097561 0.0688163108910093 0.334152832983209 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 2/820 10/18639 0.2 4.54609756097561 0.0688163108910093 0.334152832983209 GO:0043422 protein kinase B binding 2/820 10/18639 0.2 4.54609756097561 0.0688163108910093 0.334152832983209 GO:0070097 delta-catenin binding 2/820 10/18639 0.2 4.54609756097561 0.0688163108910093 0.334152832983209 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 2/820 10/18639 0.2 4.54609756097561 0.0688163108910093 0.334152832983209 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 2/820 10/18639 0.2 4.54609756097561 0.0688163108910093 0.334152832983209 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 2/820 10/18639 0.2 4.54609756097561 0.0688163108910093 0.334152832983209 GO:0030246 carbohydrate binding 18/820 280/18639 0.0642857142857143 1.4612456445993 0.0699160472391774 0.337812188640778 GO:0005021 vascular endothelial growth factor receptor activity 5/820 51/18639 0.0980392156862745 2.22847919655667 0.0725845882741742 0.347507256284265 GO:0008135 translation factor activity, RNA binding 7/820 83/18639 0.0843373493975904 1.91702909197767 0.0726347134036783 0.347507256284265 GO:0031267 small GTPase binding 18/820 283/18639 0.0636042402826855 1.44575540808412 0.0756472017233316 0.360154482351081 GO:0180051 translation factor activity 7/820 84/18639 0.0833333333333333 1.89420731707317 0.0763917780355628 0.361933860984025 GO:0030159 signaling receptor complex adaptor activity 5/820 52/18639 0.0961538461538462 2.18562382739212 0.0775462292467637 0.363275932408905 GO:0004602 glutathione peroxidase activity 3/820 23/18639 0.130434782608696 2.96484623541888 0.078163878899457 0.363275932408905 GO:0016849 phosphorus-oxygen lyase activity 3/820 23/18639 0.130434782608696 2.96484623541888 0.078163878899457 0.363275932408905 GO:0043274 phospholipase binding 3/820 23/18639 0.130434782608696 2.96484623541888 0.078163878899457 0.363275932408905 GO:0005225 volume-sensitive anion channel activity 2/820 11/18639 0.181818181818182 4.13281596452328 0.0817226543847942 0.364206898080179 GO:0008046 axon guidance receptor activity 2/820 11/18639 0.181818181818182 4.13281596452328 0.0817226543847942 0.364206898080179 GO:0008199 ferric iron binding 2/820 11/18639 0.181818181818182 4.13281596452328 0.0817226543847942 0.364206898080179 GO:0032050 clathrin heavy chain binding 2/820 11/18639 0.181818181818182 4.13281596452328 0.0817226543847942 0.364206898080179 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 2/820 11/18639 0.181818181818182 4.13281596452328 0.0817226543847942 0.364206898080179 GO:0034713 type I transforming growth factor beta receptor binding 2/820 11/18639 0.181818181818182 4.13281596452328 0.0817226543847942 0.364206898080179 GO:0042608 T cell receptor binding 2/820 11/18639 0.181818181818182 4.13281596452328 0.0817226543847942 0.364206898080179 GO:0050786 RAGE receptor binding 2/820 11/18639 0.181818181818182 4.13281596452328 0.0817226543847942 0.364206898080179 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 2/820 11/18639 0.181818181818182 4.13281596452328 0.0817226543847942 0.364206898080179 GO:0005246 calcium channel regulator activity 5/820 53/18639 0.0943396226415094 2.14438564196963 0.0826856532337045 0.365163789846586 GO:0016860 intramolecular oxidoreductase activity 5/820 53/18639 0.0943396226415094 2.14438564196963 0.0826856532337045 0.365163789846586 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 7/820 86/18639 0.0813953488372093 1.85015598411798 0.0842407887752805 0.369325075531978 GO:0005109 frizzled binding 4/820 38/18639 0.105263157894737 2.39268292682927 0.0843847252496219 0.369325075531978 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 3/820 24/18639 0.125 2.84131097560976 0.086533238994657 0.372193641624086 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 3/820 24/18639 0.125 2.84131097560976 0.086533238994657 0.372193641624086 GO:0030552 cAMP binding 3/820 24/18639 0.125 2.84131097560976 0.086533238994657 0.372193641624086 GO:0070851 growth factor receptor binding 10/820 139/18639 0.0719424460431655 1.63528689243727 0.0865655293531429 0.372193641624086 GO:0097110 scaffold protein binding 6/820 70/18639 0.0857142857142857 1.9483275261324 0.0871535138170184 0.373078199497412 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 21/820 349/18639 0.0601719197707736 1.36773708854567 0.0917240995008129 0.390794537751132 GO:0004197 cysteine-type endopeptidase activity 7/820 88/18639 0.0795454545454545 1.80810698447894 0.0925337595788578 0.390794537751132 GO:0005537 D-mannose binding 3/820 25/18639 0.12 2.72765853658537 0.095262731103623 0.390794537751132 GO:0120020 cholesterol transfer activity 3/820 25/18639 0.12 2.72765853658537 0.095262731103623 0.390794537751132 GO:0004875 complement receptor activity 2/820 12/18639 0.166666666666667 3.78841463414634 0.0952962090007884 0.390794537751132 GO:0008179 adenylate cyclase binding 2/820 12/18639 0.166666666666667 3.78841463414634 0.0952962090007884 0.390794537751132 GO:0034452 dynactin binding 2/820 12/18639 0.166666666666667 3.78841463414634 0.0952962090007884 0.390794537751132 GO:0035259 nuclear glucocorticoid receptor binding 2/820 12/18639 0.166666666666667 3.78841463414634 0.0952962090007884 0.390794537751132 GO:0141221 histone deacetylase activity, hydrolytic mechanism 2/820 12/18639 0.166666666666667 3.78841463414634 0.0952962090007884 0.390794537751132 GO:1990459 transferrin receptor binding 2/820 12/18639 0.166666666666667 3.78841463414634 0.0952962090007884 0.390794537751132 GO:0020037 heme binding 10/820 142/18639 0.0704225352112676 1.60073857780831 0.0963684063860201 0.393537927333705 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 4/820 40/18639 0.1 2.2730487804878 0.097693783165773 0.39728805154081 GO:0008083 growth factor activity 11/820 162/18639 0.0679012345679012 1.54342818428184 0.101988174893218 0.413030948945147 GO:0004112 cyclic-nucleotide phosphodiesterase activity 3/820 26/18639 0.115384615384615 2.62274859287054 0.104334839700195 0.413686572457089 GO:0004435 phosphatidylinositol phospholipase C activity 3/820 26/18639 0.115384615384615 2.62274859287054 0.104334839700195 0.413686572457089 GO:0008198 ferrous iron binding 3/820 26/18639 0.115384615384615 2.62274859287054 0.104334839700195 0.413686572457089 GO:0030507 spectrin binding 3/820 26/18639 0.115384615384615 2.62274859287054 0.104334839700195 0.413686572457089 GO:0043548 phosphatidylinositol 3-kinase binding 3/820 26/18639 0.115384615384615 2.62274859287054 0.104334839700195 0.413686572457089 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 4/820 41/18639 0.0975609756097561 2.21760856632957 0.104693220693546 0.413686572457089 GO:0005172 vascular endothelial growth factor receptor binding 2/820 13/18639 0.153846153846154 3.49699812382739 0.109453454884695 0.427306287869851 GO:0008035 high-density lipoprotein particle binding 2/820 13/18639 0.153846153846154 3.49699812382739 0.109453454884695 0.427306287869851 GO:0019855 calcium channel inhibitor activity 2/820 13/18639 0.153846153846154 3.49699812382739 0.109453454884695 0.427306287869851 GO:0051879 Hsp90 protein binding 4/820 42/18639 0.0952380952380952 2.16480836236934 0.11191389513346 0.435171161953213 GO:0004364 glutathione transferase activity 3/820 27/18639 0.111111111111111 2.52560975609756 0.113731561434108 0.440484142697179 GO:0035591 signaling adaptor activity 9/820 129/18639 0.0697674418604651 1.58584798638684 0.115534776221143 0.444965832010812 GO:1902936 phosphatidylinositol bisphosphate binding 8/820 111/18639 0.0720720720720721 1.63823335530653 0.116062230047221 0.444965832010812 GO:0003714 transcription corepressor activity 13/820 204/18639 0.0637254901960784 1.44851147776184 0.11625644176512 0.444965832010812 GO:0004879 nuclear receptor activity 5/820 59/18639 0.0847457627118644 1.92631252583712 0.117123497947372 0.446533335924355 GO:0016247 channel regulator activity 11/820 168/18639 0.0654761904761905 1.48830574912892 0.122705715297469 0.462359190706104 GO:0051959 dynein light intermediate chain binding 3/820 28/18639 0.107142857142857 2.43540940766551 0.123434539959541 0.462359190706104 GO:0004714 transmembrane receptor protein tyrosine kinase activity 5/820 60/18639 0.0833333333333333 1.89420731707317 0.12343563993945 0.462359190706104 GO:0098531 ligand-modulated transcription factor activity 5/820 60/18639 0.0833333333333333 1.89420731707317 0.12343563993945 0.462359190706104 GO:0016530 metallochaperone activity 2/820 14/18639 0.142857142857143 3.24721254355401 0.124116913898565 0.462359190706104 GO:0019992 diacylglycerol binding 2/820 14/18639 0.142857142857143 3.24721254355401 0.124116913898565 0.462359190706104 GO:0141108 transporter regulator activity 11/820 170/18639 0.0647058823529412 1.4707962697274 0.130097261519196 0.482794400162491 GO:0004629 phospholipase C activity 3/820 29/18639 0.103448275862069 2.35142977291842 0.133425187336576 0.488133762320733 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 3/820 29/18639 0.103448275862069 2.35142977291842 0.133425187336576 0.488133762320733 GO:0099604 ligand-gated calcium channel activity 3/820 29/18639 0.103448275862069 2.35142977291842 0.133425187336576 0.488133762320733 GO:0046906 tetrapyrrole binding 10/820 152/18639 0.0657894736842105 1.49542682926829 0.13353659276602 0.488133762320733 GO:0016846 carbon-sulfur lyase activity 2/820 15/18639 0.133333333333333 3.03073170731707 0.139214780724542 0.49953538965865 GO:0120283 protein serine/threonine kinase binding 2/820 15/18639 0.133333333333333 3.03073170731707 0.139214780724542 0.49953538965865 GO:0140776 protein-containing complex destabilizing activity 2/820 15/18639 0.133333333333333 3.03073170731707 0.139214780724542 0.49953538965865 GO:0141050 histone H3K deacetylase activity 2/820 15/18639 0.133333333333333 3.03073170731707 0.139214780724542 0.49953538965865 GO:0141051 histone H4K deacetylase activity 2/820 15/18639 0.133333333333333 3.03073170731707 0.139214780724542 0.49953538965865 GO:0030291 protein serine/threonine kinase inhibitor activity 4/820 46/18639 0.0869565217391304 1.97656415694592 0.142864188547606 0.50919189623899 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 3/820 30/18639 0.1 2.2730487804878 0.143684793033649 0.50919189623899 GO:0019208 phosphatase regulator activity 8/820 117/18639 0.0683760683760684 1.55422138836773 0.143888241107586 0.50919189623899 GO:0003924 GTPase activity 19/820 331/18639 0.0574018126888218 1.30477120330116 0.143992790329878 0.50919189623899 GO:0005504 fatty acid binding 4/820 47/18639 0.0851063829787234 1.93450960041515 0.151079954652138 0.532325038774322 GO:0005164 tumor necrosis factor receptor binding 3/820 31/18639 0.0967741935483871 2.19972462627852 0.154194621490058 0.533456681552542 GO:0070273 phosphatidylinositol-4-phosphate binding 3/820 31/18639 0.0967741935483871 2.19972462627852 0.154194621490058 0.533456681552542 GO:0005521 lamin binding 2/820 16/18639 0.125 2.84131097560976 0.154680574671485 0.533456681552542 GO:0015923 mannosidase activity 2/820 16/18639 0.125 2.84131097560976 0.154680574671485 0.533456681552542 GO:0031435 mitogen-activated protein kinase kinase kinase binding 2/820 16/18639 0.125 2.84131097560976 0.154680574671485 0.533456681552542 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/820 16/18639 0.125 2.84131097560976 0.154680574671485 0.533456681552542 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 4/820 48/18639 0.0833333333333333 1.89420731707317 0.159470712332477 0.548040194494711 GO:0008238 exopeptidase activity 7/820 102/18639 0.0686274509803922 1.55993543758967 0.162387735455113 0.556106771242773 GO:0120015 sterol transfer activity 3/820 32/18639 0.09375 2.13098323170732 0.164935999132799 0.562858514523119 GO:0099106 ion channel regulator activity 10/820 160/18639 0.0625 1.42065548780488 0.168018057698945 0.569428264256096 GO:0060590 ATPase regulator activity 4/820 49/18639 0.0816326530612245 1.855550024888 0.168028012403438 0.569428264256096 GO:0004550 nucleoside diphosphate kinase activity 2/820 17/18639 0.117647058823529 2.67417503586801 0.170452811080245 0.569732683610682 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/820 17/18639 0.117647058823529 2.67417503586801 0.170452811080245 0.569732683610682 GO:0016805 dipeptidase activity 2/820 17/18639 0.117647058823529 2.67417503586801 0.170452811080245 0.569732683610682 GO:0046965 nuclear retinoid X receptor binding 2/820 17/18639 0.117647058823529 2.67417503586801 0.170452811080245 0.569732683610682 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 5/820 67/18639 0.0746268656716418 1.69630506006553 0.17170213880871 0.571949786611949 GO:0004866 endopeptidase inhibitor activity 10/820 161/18639 0.062111801242236 1.41183154067566 0.172605300550517 0.573002630398997 GO:0005261 monoatomic cation channel activity 19/820 341/18639 0.0557184750733138 1.26650811816036 0.173859893071981 0.575211036061875 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 3/820 33/18639 0.0909090909090909 2.06640798226164 0.17589039168123 0.579962913111083 GO:0003743 translation initiation factor activity 4/820 51/18639 0.0784313725490196 1.78278335724534 0.185607851017428 0.602476980778111 GO:0005216 monoatomic ion channel activity 24/820 448/18639 0.0535714285714286 1.21770470383275 0.186107986386015 0.602476980778111 GO:0015172 acidic amino acid transmembrane transporter activity 2/820 18/18639 0.111111111111111 2.52560975609756 0.1864746912803 0.602476980778111 GO:0031690 adrenergic receptor binding 2/820 18/18639 0.111111111111111 2.52560975609756 0.1864746912803 0.602476980778111 GO:0050811 GABA receptor binding 2/820 18/18639 0.111111111111111 2.52560975609756 0.1864746912803 0.602476980778111 GO:1990381 ubiquitin-specific protease binding 2/820 18/18639 0.111111111111111 2.52560975609756 0.1864746912803 0.602476980778111 GO:0019825 oxygen binding 3/820 34/18639 0.0882352941176471 2.005631276901 0.187039472516155 0.602476980778111 GO:0046982 protein heterodimerization activity 20/820 369/18639 0.0542005420054201 1.23200475907198 0.197787848348336 0.63500309206571 GO:0003712 transcription coregulator activity 26/820 495/18639 0.0525252525252525 1.19392461197339 0.201086285232047 0.64347611274255 GO:0005516 calmodulin binding 12/820 207/18639 0.0579710144927536 1.31770943796394 0.202099383449013 0.644604569432145 GO:0140296 general transcription initiation factor binding 4/820 53/18639 0.0754716981132075 1.7155085135757 0.20374991130223 0.647004532506763 GO:0004620 phospholipase activity 7/820 109/18639 0.0642201834862385 1.45975609756098 0.204177659848446 0.647004532506763 GO:0030414 peptidase inhibitor activity 10/820 169/18639 0.0591715976331361 1.34499927839515 0.211327123030523 0.667492789895762 GO:0003925 G protein activity 4/820 54/18639 0.0740740740740741 1.68373983739837 0.213009835399412 0.670637417257503 GO:0000339 RNA cap binding 2/820 20/18639 0.1 2.2730487804878 0.219061880019917 0.680905716240252 GO:0016004 phospholipase activator activity 2/820 20/18639 0.1 2.2730487804878 0.219061880019917 0.680905716240252 GO:0030742 GTP-dependent protein binding 2/820 20/18639 0.1 2.2730487804878 0.219061880019917 0.680905716240252 GO:0140939 histone H4 methyltransferase activity 2/820 20/18639 0.1 2.2730487804878 0.219061880019917 0.680905716240252 GO:0030551 cyclic nucleotide binding 3/820 37/18639 0.0810810810810811 1.84301252471984 0.221475904611068 0.686223755239372 GO:0170055 lipid transmembrane transporter activity 4/820 56/18639 0.0714285714285714 1.623606271777 0.231863577844267 0.711707875165031 GO:0000146 microfilament motor activity 3/820 38/18639 0.0789473684210526 1.79451219512195 0.233226577127763 0.711707875165031 GO:0043531 ADP binding 3/820 38/18639 0.0789473684210526 1.79451219512195 0.233226577127763 0.711707875165031 GO:0003725 double-stranded RNA binding 5/820 75/18639 0.0666666666666667 1.51536585365854 0.234107836417529 0.711707875165031 GO:0008373 sialyltransferase activity 2/820 21/18639 0.0952380952380952 2.16480836236934 0.23553447098187 0.711707875165031 GO:0009975 cyclase activity 2/820 21/18639 0.0952380952380952 2.16480836236934 0.23553447098187 0.711707875165031 GO:0010314 phosphatidylinositol-5-phosphate binding 2/820 21/18639 0.0952380952380952 2.16480836236934 0.23553447098187 0.711707875165031 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/820 21/18639 0.0952380952380952 2.16480836236934 0.23553447098187 0.711707875165031 GO:0051087 protein-folding chaperone binding 8/820 134/18639 0.0597014925373134 1.35704404805242 0.237729959755799 0.71612481704216 GO:0098631 cell adhesion mediator activity 5/820 76/18639 0.0657894736842105 1.49542682926829 0.242329284529148 0.727733482155226 GO:0016776 phosphotransferase activity, phosphate group as acceptor 3/820 39/18639 0.0769230769230769 1.7484990619137 0.245085274213049 0.731508341382068 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 3/820 39/18639 0.0769230769230769 1.7484990619137 0.245085274213049 0.731508341382068 GO:0004407 histone deacetylase activity 2/820 22/18639 0.0909090909090909 2.06640798226164 0.252070765163785 0.745518384241982 GO:0031683 G-protein beta/gamma-subunit complex binding 2/820 22/18639 0.0909090909090909 2.06640798226164 0.252070765163785 0.745518384241982 GO:0033558 protein lysine deacetylase activity 2/820 22/18639 0.0909090909090909 2.06640798226164 0.252070765163785 0.745518384241982 GO:0016922 nuclear receptor binding 8/820 137/18639 0.0583941605839416 1.32732775502937 0.256153800108973 0.755305464973889 GO:0071855 neuropeptide receptor binding 3/820 40/18639 0.075 1.70478658536585 0.257035935649315 0.75562371443895 GO:0019199 transmembrane receptor protein kinase activity 5/820 78/18639 0.0641025641025641 1.45708255159475 0.258994025308156 0.759093599701983 GO:0042626 ATPase-coupled transmembrane transporter activity 6/820 98/18639 0.0612244897959184 1.391662518666 0.262265095088443 0.766379439539882 GO:0016829 lyase activity 11/820 200/18639 0.055 1.25017682926829 0.266461734517344 0.776318366832621 GO:0017134 fibroblast growth factor binding 2/820 23/18639 0.0869565217391304 1.97656415694592 0.268633325760389 0.776939290777973 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 2/820 23/18639 0.0869565217391304 1.97656415694592 0.268633325760389 0.776939290777973 GO:0008227 G protein-coupled amine receptor activity 3/820 41/18639 0.0731707317073171 1.66320642474717 0.269062992093191 0.776939290777973 GO:0008307 structural constituent of muscle 3/820 42/18639 0.0714285714285714 1.623606271777 0.281151384167017 0.799837270127191 GO:0019894 kinesin binding 3/820 42/18639 0.0714285714285714 1.623606271777 0.281151384167017 0.799837270127191 GO:0048487 beta-tubulin binding 3/820 42/18639 0.0714285714285714 1.623606271777 0.281151384167017 0.799837270127191 GO:0051082 unfolded protein binding 7/820 121/18639 0.0578512396694215 1.31498689780286 0.283673378278395 0.799837270127191 GO:0001091 RNA polymerase II general transcription initiation factor binding 2/820 24/18639 0.0833333333333333 1.89420731707317 0.285187879102728 0.799837270127191 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2/820 24/18639 0.0833333333333333 1.89420731707317 0.285187879102728 0.799837270127191 GO:0035035 histone acetyltransferase binding 2/820 24/18639 0.0833333333333333 1.89420731707317 0.285187879102728 0.799837270127191 GO:0060229 lipase activator activity 2/820 24/18639 0.0833333333333333 1.89420731707317 0.285187879102728 0.799837270127191 GO:0070300 phosphatidic acid binding 2/820 24/18639 0.0833333333333333 1.89420731707317 0.285187879102728 0.799837270127191 GO:0070840 dynein complex binding 2/820 24/18639 0.0833333333333333 1.89420731707317 0.285187879102728 0.799837270127191 GO:0005245 voltage-gated calcium channel activity 3/820 43/18639 0.0697674418604651 1.58584798638684 0.293286577565213 0.814351988226421 GO:0048156 tau protein binding 3/820 43/18639 0.0697674418604651 1.58584798638684 0.293286577565213 0.814351988226421 GO:0005507 copper ion binding 4/820 63/18639 0.0634920634920635 1.44320557491289 0.300453555271981 0.814351988226421 GO:0030165 PDZ domain binding 5/820 83/18639 0.0602409638554217 1.36930649426976 0.301701189226161 0.814351988226421 GO:0003707 nuclear steroid receptor activity 2/820 25/18639 0.08 1.81843902439024 0.30170310936352 0.814351988226421 GO:0015662 P-type ion transporter activity 2/820 25/18639 0.08 1.81843902439024 0.30170310936352 0.814351988226421 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2/820 25/18639 0.08 1.81843902439024 0.30170310936352 0.814351988226421 GO:0017025 TBP-class protein binding 2/820 25/18639 0.08 1.81843902439024 0.30170310936352 0.814351988226421 GO:0042974 nuclear retinoic acid receptor binding 2/820 25/18639 0.08 1.81843902439024 0.30170310936352 0.814351988226421 GO:0140358 P-type transmembrane transporter activity 2/820 25/18639 0.08 1.81843902439024 0.30170310936352 0.814351988226421 GO:0019205 nucleobase-containing compound kinase activity 3/820 44/18639 0.0681818181818182 1.54980598669623 0.305454574547701 0.814351988226421 GO:0019001 guanyl nucleotide binding 20/820 400/18639 0.05 1.1365243902439 0.309691693105951 0.814351988226421 GO:0032561 guanyl ribonucleotide binding 20/820 400/18639 0.05 1.1365243902439 0.309691693105951 0.814351988226421 GO:0005112 Notch binding 2/820 26/18639 0.0769230769230769 1.7484990619137 0.318150465168797 0.814351988226421 GO:0005160 transforming growth factor beta receptor binding 2/820 26/18639 0.0769230769230769 1.7484990619137 0.318150465168797 0.814351988226421 GO:0034237 protein kinase A regulatory subunit binding 2/820 26/18639 0.0769230769230769 1.7484990619137 0.318150465168797 0.814351988226421 GO:0050681 nuclear androgen receptor binding 2/820 26/18639 0.0769230769230769 1.7484990619137 0.318150465168797 0.814351988226421 GO:0070412 R-SMAD binding 2/820 26/18639 0.0769230769230769 1.7484990619137 0.318150465168797 0.814351988226421 GO:0008013 beta-catenin binding 6/820 106/18639 0.0566037735849057 1.28663138518178 0.323644475428715 0.814351988226421 GO:0019902 phosphatase binding 10/820 190/18639 0.0526315789473684 1.19634146341463 0.326412726859711 0.814351988226421 GO:0008235 metalloexopeptidase activity 4/820 66/18639 0.0606060606060606 1.37760532150776 0.330592519273106 0.814351988226421 GO:0019888 protein phosphatase regulator activity 6/820 107/18639 0.0560747663551402 1.2746067927969 0.331474760486569 0.814351988226421 GO:0001671 ATPase activator activity 2/820 27/18639 0.0740740740740741 1.68373983739837 0.334503977467571 0.814351988226421 GO:0035255 ionotropic glutamate receptor binding 2/820 27/18639 0.0740740740740741 1.68373983739837 0.334503977467571 0.814351988226421 GO:0015631 tubulin binding 19/820 385/18639 0.0493506493506494 1.12176433322775 0.336098445925966 0.814351988226421 GO:0043495 protein-membrane adaptor activity 3/820 47/18639 0.0638297872340425 1.45088220031136 0.342023610457355 0.814351988226421 GO:0016298 lipase activity 7/820 130/18639 0.0538461538461538 1.22394934333959 0.347460114039957 0.814351988226421 GO:0016798 hydrolase activity, acting on glycosyl bonds 7/820 130/18639 0.0538461538461538 1.22394934333959 0.347460114039957 0.814351988226421 GO:0046625 sphingolipid binding 2/820 28/18639 0.0714285714285714 1.623606271777 0.350740088045112 0.814351988226421 GO:0050698 proteoglycan sulfotransferase activity 2/820 28/18639 0.0714285714285714 1.623606271777 0.350740088045112 0.814351988226421 GO:0051019 mitogen-activated protein kinase binding 2/820 28/18639 0.0714285714285714 1.623606271777 0.350740088045112 0.814351988226421 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 5/820 89/18639 0.0561797752808989 1.27699369690326 0.354178057622596 0.814351988226421 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 5/820 89/18639 0.0561797752808989 1.27699369690326 0.354178057622596 0.814351988226421 GO:0032266 phosphatidylinositol-3-phosphate binding 3/820 48/18639 0.0625 1.42065548780488 0.35419380366568 0.814351988226421 GO:0004222 metalloendopeptidase activity 6/820 110/18639 0.0545454545454545 1.23984478935698 0.355089797092783 0.814351988226421 GO:0001094 TFIID-class transcription factor complex binding 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0003796 lysozyme activity 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0004935 adrenergic receptor activity 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0004955 prostaglandin receptor activity 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0005345 purine nucleobase transmembrane transporter activity 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0005381 iron ion transmembrane transporter activity 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0005522 profilin binding 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0005528 FK506 binding 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0008140 cAMP response element binding protein binding 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0008239 dipeptidyl-peptidase activity 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0019911 structural constituent of myelin sheath 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0030957 Tat protein binding 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0031996 thioesterase binding 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0035374 chondroitin sulfate binding 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0043121 neurotrophin binding 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0043208 glycosphingolipid binding 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0045322 unmethylated CpG binding 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0047429 nucleoside triphosphate diphosphatase activity 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0050815 phosphoserine residue binding 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0051864 histone H3K36 demethylase activity 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0051880 G-quadruplex DNA binding 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0070513 death domain binding 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0071723 lipopeptide binding 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0140999 histone H3K4 trimethyltransferase activity 1/820 10/18639 0.1 2.2730487804878 0.362384409725832 0.814351988226421 GO:0140793 histone H2AXY142 phosphatase activity 5/820 90/18639 0.0555555555555556 1.26280487804878 0.362984695205677 0.814351988226421 GO:0001222 transcription corepressor binding 3/820 49/18639 0.0612244897959184 1.391662518666 0.366335050921913 0.814351988226421 GO:0005004 GPI-linked ephrin receptor activity 3/820 49/18639 0.0612244897959184 1.391662518666 0.366335050921913 0.814351988226421 GO:0005008 hepatocyte growth factor receptor activity 3/820 49/18639 0.0612244897959184 1.391662518666 0.366335050921913 0.814351988226421 GO:0005009 insulin receptor activity 3/820 49/18639 0.0612244897959184 1.391662518666 0.366335050921913 0.814351988226421 GO:0005011 macrophage colony-stimulating factor receptor activity 3/820 49/18639 0.0612244897959184 1.391662518666 0.366335050921913 0.814351988226421 GO:0005018 platelet-derived growth factor alpha-receptor activity 3/820 49/18639 0.0612244897959184 1.391662518666 0.366335050921913 0.814351988226421 GO:0005020 stem cell factor receptor activity 3/820 49/18639 0.0612244897959184 1.391662518666 0.366335050921913 0.814351988226421 GO:0008288 boss receptor activity 3/820 49/18639 0.0612244897959184 1.391662518666 0.366335050921913 0.814351988226421 GO:0036332 placental growth factor receptor activity 3/820 49/18639 0.0612244897959184 1.391662518666 0.366335050921913 0.814351988226421 GO:0038062 protein tyrosine kinase collagen receptor activity 3/820 49/18639 0.0612244897959184 1.391662518666 0.366335050921913 0.814351988226421 GO:0060175 brain-derived neurotrophic factor receptor activity 3/820 49/18639 0.0612244897959184 1.391662518666 0.366335050921913 0.814351988226421 GO:0051861 glycolipid binding 2/820 29/18639 0.0689655172413793 1.56761984861228 0.366837488097597 0.814351988226421 GO:0008028 monocarboxylic acid transmembrane transporter activity 4/820 70/18639 0.0571428571428571 1.2988850174216 0.370971084128571 0.814351988226421 GO:0043021 ribonucleoprotein complex binding 9/820 177/18639 0.0508474576271186 1.15578751550227 0.376860220704041 0.814351988226421 GO:0005006 epidermal growth factor receptor activity 3/820 50/18639 0.06 1.36382926829268 0.378436653232428 0.814351988226421 GO:0005007 fibroblast growth factor receptor activity 3/820 50/18639 0.06 1.36382926829268 0.378436653232428 0.814351988226421 GO:0005017 platelet-derived growth factor receptor activity 3/820 50/18639 0.06 1.36382926829268 0.378436653232428 0.814351988226421 GO:0005019 platelet-derived growth factor beta-receptor activity 3/820 50/18639 0.06 1.36382926829268 0.378436653232428 0.814351988226421 GO:0032813 tumor necrosis factor receptor superfamily binding 3/820 50/18639 0.06 1.36382926829268 0.378436653232428 0.814351988226421 GO:0140299 molecular sensor activity 4/820 71/18639 0.0563380281690141 1.28059086224665 0.381053746410757 0.814351988226421 GO:0001965 G-protein alpha-subunit binding 2/820 30/18639 0.0666666666666667 1.51536585365854 0.38277696631645 0.814351988226421 GO:0001968 fibronectin binding 2/820 30/18639 0.0666666666666667 1.51536585365854 0.38277696631645 0.814351988226421 GO:0031210 phosphatidylcholine binding 2/820 30/18639 0.0666666666666667 1.51536585365854 0.38277696631645 0.814351988226421 GO:0005319 lipid transporter activity 9/820 178/18639 0.050561797752809 1.14929432721294 0.383154619765511 0.814351988226421 GO:0051213 dioxygenase activity 5/820 93/18639 0.0537634408602151 1.2220692368214 0.389414638465623 0.814351988226421 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/820 11/18639 0.0909090909090909 2.06640798226164 0.390450585259935 0.814351988226421 GO:0003953 NAD+ nucleosidase activity 1/820 11/18639 0.0909090909090909 2.06640798226164 0.390450585259935 0.814351988226421 GO:0004954 prostanoid receptor activity 1/820 11/18639 0.0909090909090909 2.06640798226164 0.390450585259935 0.814351988226421 GO:0008271 secondary active sulfate transmembrane transporter activity 1/820 11/18639 0.0909090909090909 2.06640798226164 0.390450585259935 0.814351988226421 GO:0008526 phosphatidylinositol transfer activity 1/820 11/18639 0.0909090909090909 2.06640798226164 0.390450585259935 0.814351988226421 GO:0015173 aromatic amino acid transmembrane transporter activity 1/820 11/18639 0.0909090909090909 2.06640798226164 0.390450585259935 0.814351988226421 GO:0015205 nucleobase transmembrane transporter activity 1/820 11/18639 0.0909090909090909 2.06640798226164 0.390450585259935 0.814351988226421 GO:0015217 ADP transmembrane transporter activity 1/820 11/18639 0.0909090909090909 2.06640798226164 0.390450585259935 0.814351988226421 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/820 11/18639 0.0909090909090909 2.06640798226164 0.390450585259935 0.814351988226421 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/820 11/18639 0.0909090909090909 2.06640798226164 0.390450585259935 0.814351988226421 GO:0019215 intermediate filament binding 1/820 11/18639 0.0909090909090909 2.06640798226164 0.390450585259935 0.814351988226421 GO:0032794 GTPase activating protein binding 1/820 11/18639 0.0909090909090909 2.06640798226164 0.390450585259935 0.814351988226421 GO:0034056 estrogen response element binding 1/820 11/18639 0.0909090909090909 2.06640798226164 0.390450585259935 0.814351988226421 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/820 11/18639 0.0909090909090909 2.06640798226164 0.390450585259935 0.814351988226421 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/820 11/18639 0.0909090909090909 2.06640798226164 0.390450585259935 0.814351988226421 GO:0047676 arachidonate-CoA ligase activity 1/820 11/18639 0.0909090909090909 2.06640798226164 0.390450585259935 0.814351988226421 GO:0050998 nitric-oxide synthase binding 1/820 11/18639 0.0909090909090909 2.06640798226164 0.390450585259935 0.814351988226421 GO:0070697 activin receptor binding 1/820 11/18639 0.0909090909090909 2.06640798226164 0.390450585259935 0.814351988226421 GO:0070990 snRNP binding 1/820 11/18639 0.0909090909090909 2.06640798226164 0.390450585259935 0.814351988226421 GO:0097493 structural molecule activity conferring elasticity 1/820 11/18639 0.0909090909090909 2.06640798226164 0.390450585259935 0.814351988226421 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/820 11/18639 0.0909090909090909 2.06640798226164 0.390450585259935 0.814351988226421 GO:0140537 transcription regulator activator activity 1/820 11/18639 0.0909090909090909 2.06640798226164 0.390450585259935 0.814351988226421 GO:0005010 insulin-like growth factor receptor activity 3/820 51/18639 0.0588235294117647 1.337087517934 0.390488453370866 0.814351988226421 GO:0005030 neurotrophin receptor activity 3/820 51/18639 0.0588235294117647 1.337087517934 0.390488453370866 0.814351988226421 GO:0016830 carbon-carbon lyase activity 3/820 51/18639 0.0588235294117647 1.337087517934 0.390488453370866 0.814351988226421 GO:0030544 Hsp70 protein binding 3/820 51/18639 0.0588235294117647 1.337087517934 0.390488453370866 0.814351988226421 GO:0005184 neuropeptide hormone activity 2/820 31/18639 0.0645161290322581 1.46648308418568 0.398541265959649 0.819452744572817 GO:0017147 Wnt-protein binding 2/820 31/18639 0.0645161290322581 1.46648308418568 0.398541265959649 0.819452744572817 GO:0004867 serine-type endopeptidase inhibitor activity 5/820 95/18639 0.0526315789473684 1.19634146341463 0.406998996023309 0.819452744572817 GO:0048029 monosaccharide binding 4/820 74/18639 0.0540540540540541 1.22867501647989 0.411170423914767 0.819452744572817 GO:0160041 neuropeptide activity 2/820 32/18639 0.0625 1.42065548780488 0.414114950414772 0.819452744572817 GO:0005003 ephrin receptor activity 3/820 53/18639 0.0566037735849057 1.28663138518178 0.414404683970794 0.819452744572817 GO:0005005 transmembrane-ephrin receptor activity 3/820 53/18639 0.0566037735849057 1.28663138518178 0.414404683970794 0.819452744572817 GO:0008146 sulfotransferase activity 3/820 53/18639 0.0566037735849057 1.28663138518178 0.414404683970794 0.819452744572817 GO:0038064 collagen receptor activity 3/820 53/18639 0.0566037735849057 1.28663138518178 0.414404683970794 0.819452744572817 GO:0051018 protein kinase A binding 3/820 53/18639 0.0566037735849057 1.28663138518178 0.414404683970794 0.819452744572817 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/820 12/18639 0.0833333333333333 1.89420731707317 0.417282801283494 0.819452744572817 GO:0004032 aldose reductase (NADPH) activity 1/820 12/18639 0.0833333333333333 1.89420731707317 0.417282801283494 0.819452744572817 GO:0004859 phospholipase inhibitor activity 1/820 12/18639 0.0833333333333333 1.89420731707317 0.417282801283494 0.819452744572817 GO:0005165 neurotrophin receptor binding 1/820 12/18639 0.0833333333333333 1.89420731707317 0.417282801283494 0.819452744572817 GO:0005247 voltage-gated chloride channel activity 1/820 12/18639 0.0833333333333333 1.89420731707317 0.417282801283494 0.819452744572817 GO:0005527 macrolide binding 1/820 12/18639 0.0833333333333333 1.89420731707317 0.417282801283494 0.819452744572817 GO:0008603 cAMP-dependent protein kinase regulator activity 1/820 12/18639 0.0833333333333333 1.89420731707317 0.417282801283494 0.819452744572817 GO:0015132 prostaglandin transmembrane transporter activity 1/820 12/18639 0.0833333333333333 1.89420731707317 0.417282801283494 0.819452744572817 GO:0015166 polyol transmembrane transporter activity 1/820 12/18639 0.0833333333333333 1.89420731707317 0.417282801283494 0.819452744572817 GO:0016208 AMP binding 1/820 12/18639 0.0833333333333333 1.89420731707317 0.417282801283494 0.819452744572817 GO:0017166 vinculin binding 1/820 12/18639 0.0833333333333333 1.89420731707317 0.417282801283494 0.819452744572817 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/820 12/18639 0.0833333333333333 1.89420731707317 0.417282801283494 0.819452744572817 GO:0045295 gamma-catenin binding 1/820 12/18639 0.0833333333333333 1.89420731707317 0.417282801283494 0.819452744572817 GO:0070008 serine-type exopeptidase activity 1/820 12/18639 0.0833333333333333 1.89420731707317 0.417282801283494 0.819452744572817 GO:0070679 inositol 1,4,5 trisphosphate binding 1/820 12/18639 0.0833333333333333 1.89420731707317 0.417282801283494 0.819452744572817 GO:0097677 STAT family protein binding 1/820 12/18639 0.0833333333333333 1.89420731707317 0.417282801283494 0.819452744572817 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/820 12/18639 0.0833333333333333 1.89420731707317 0.417282801283494 0.819452744572817 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/820 12/18639 0.0833333333333333 1.89420731707317 0.417282801283494 0.819452744572817 GO:1990247 N6-methyladenosine-containing RNA reader activity 1/820 12/18639 0.0833333333333333 1.89420731707317 0.417282801283494 0.819452744572817 GO:0008237 metallopeptidase activity 9/820 184/18639 0.0489130434782609 1.11181733828208 0.421003482687765 0.822076564427799 GO:0019003 GDP binding 4/820 75/18639 0.0533333333333333 1.21229268292683 0.421145780956864 0.822076564427799 GO:0044183 protein folding chaperone 4/820 75/18639 0.0533333333333333 1.21229268292683 0.421145780956864 0.822076564427799 GO:0051287 NAD binding 3/820 54/18639 0.0555555555555556 1.26280487804878 0.42625143976911 0.83038204633663 GO:0017022 myosin binding 4/820 76/18639 0.0526315789473684 1.19634146341463 0.431080030758404 0.834549590773511 GO:0004725 protein tyrosine phosphatase activity 5/820 98/18639 0.0510204081632653 1.159718765555 0.433238958765339 0.834549590773511 GO:0008234 cysteine-type peptidase activity 9/820 187/18639 0.0481283422459893 1.09398069649146 0.439908150721921 0.834549590773511 GO:0004535 poly(A)-specific ribonuclease activity 1/820 13/18639 0.0769230769230769 1.7484990619137 0.442935246816727 0.834549590773511 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/820 13/18639 0.0769230769230769 1.7484990619137 0.442935246816727 0.834549590773511 GO:0005542 folic acid binding 1/820 13/18639 0.0769230769230769 1.7484990619137 0.442935246816727 0.834549590773511 GO:0031994 insulin-like growth factor I binding 1/820 13/18639 0.0769230769230769 1.7484990619137 0.442935246816727 0.834549590773511 GO:0032396 inhibitory MHC class I receptor activity 1/820 13/18639 0.0769230769230769 1.7484990619137 0.442935246816727 0.834549590773511 GO:0035673 oligopeptide transmembrane transporter activity 1/820 13/18639 0.0769230769230769 1.7484990619137 0.442935246816727 0.834549590773511 GO:0039706 co-receptor binding 1/820 13/18639 0.0769230769230769 1.7484990619137 0.442935246816727 0.834549590773511 GO:0043560 insulin receptor substrate binding 1/820 13/18639 0.0769230769230769 1.7484990619137 0.442935246816727 0.834549590773511 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/820 13/18639 0.0769230769230769 1.7484990619137 0.442935246816727 0.834549590773511 GO:0046975 histone H3K36 methyltransferase activity 1/820 13/18639 0.0769230769230769 1.7484990619137 0.442935246816727 0.834549590773511 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/820 13/18639 0.0769230769230769 1.7484990619137 0.442935246816727 0.834549590773511 GO:0071714 icosanoid transmembrane transporter activity 1/820 13/18639 0.0769230769230769 1.7484990619137 0.442935246816727 0.834549590773511 GO:0071837 HMG box domain binding 1/820 13/18639 0.0769230769230769 1.7484990619137 0.442935246816727 0.834549590773511 GO:0016831 carboxy-lyase activity 2/820 34/18639 0.0588235294117647 1.337087517934 0.444637077051461 0.834549590773511 GO:0030332 cyclin binding 2/820 34/18639 0.0588235294117647 1.337087517934 0.444637077051461 0.834549590773511 GO:0051427 hormone receptor binding 2/820 34/18639 0.0588235294117647 1.337087517934 0.444637077051461 0.834549590773511 GO:0019903 protein phosphatase binding 7/820 144/18639 0.0486111111111111 1.10495426829268 0.448730955809122 0.840616915296936 GO:0043177 organic acid binding 9/820 189/18639 0.0476190476190476 1.08240418118467 0.452475319710253 0.846007494324151 GO:0033293 monocarboxylic acid binding 4/820 79/18639 0.0506329113924051 1.15091077493053 0.460584467428299 0.848031041541144 GO:0004705 JUN kinase activity 1/820 14/18639 0.0714285714285714 1.623606271777 0.467459733964278 0.848031041541144 GO:0005313 L-glutamate transmembrane transporter activity 1/820 14/18639 0.0714285714285714 1.623606271777 0.467459733964278 0.848031041541144 GO:0005347 ATP transmembrane transporter activity 1/820 14/18639 0.0714285714285714 1.623606271777 0.467459733964278 0.848031041541144 GO:0008191 metalloendopeptidase inhibitor activity 1/820 14/18639 0.0714285714285714 1.623606271777 0.467459733964278 0.848031041541144 GO:0008331 high voltage-gated calcium channel activity 1/820 14/18639 0.0714285714285714 1.623606271777 0.467459733964278 0.848031041541144 GO:0015386 potassium:proton antiporter activity 1/820 14/18639 0.0714285714285714 1.623606271777 0.467459733964278 0.848031041541144 GO:0031404 chloride ion binding 1/820 14/18639 0.0714285714285714 1.623606271777 0.467459733964278 0.848031041541144 GO:0032036 myosin heavy chain binding 1/820 14/18639 0.0714285714285714 1.623606271777 0.467459733964278 0.848031041541144 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/820 14/18639 0.0714285714285714 1.623606271777 0.467459733964278 0.848031041541144 GO:0042043 neurexin family protein binding 1/820 14/18639 0.0714285714285714 1.623606271777 0.467459733964278 0.848031041541144 GO:0044548 S100 protein binding 1/820 14/18639 0.0714285714285714 1.623606271777 0.467459733964278 0.848031041541144 GO:0046030 inositol trisphosphate phosphatase activity 1/820 14/18639 0.0714285714285714 1.623606271777 0.467459733964278 0.848031041541144 GO:0061783 peptidoglycan muralytic activity 1/820 14/18639 0.0714285714285714 1.623606271777 0.467459733964278 0.848031041541144 GO:0071933 Arp2/3 complex binding 1/820 14/18639 0.0714285714285714 1.623606271777 0.467459733964278 0.848031041541144 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/820 14/18639 0.0714285714285714 1.623606271777 0.467459733964278 0.848031041541144 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/820 36/18639 0.0555555555555556 1.26280487804878 0.474251638287302 0.852430200678465 GO:0045505 dynein intermediate chain binding 2/820 36/18639 0.0555555555555556 1.26280487804878 0.474251638287302 0.852430200678465 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 2/820 36/18639 0.0555555555555556 1.26280487804878 0.474251638287302 0.852430200678465 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 2/820 36/18639 0.0555555555555556 1.26280487804878 0.474251638287302 0.852430200678465 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 2/820 36/18639 0.0555555555555556 1.26280487804878 0.474251638287302 0.852430200678465 GO:0001786 phosphatidylserine binding 3/820 59/18639 0.0508474576271186 1.15578751550227 0.484063293894426 0.855578683577791 GO:0070063 RNA polymerase binding 3/820 59/18639 0.0508474576271186 1.15578751550227 0.484063293894426 0.855578683577791 GO:0019213 deacetylase activity 2/820 37/18639 0.0540540540540541 1.22867501647989 0.488695965925943 0.855578683577791 GO:0042805 actinin binding 2/820 37/18639 0.0540540540540541 1.22867501647989 0.488695965925943 0.855578683577791 GO:0000774 adenyl-nucleotide exchange factor activity 1/820 15/18639 0.0666666666666667 1.51536585365854 0.490905802052831 0.855578683577791 GO:0004467 long-chain fatty acid-CoA ligase activity 1/820 15/18639 0.0666666666666667 1.51536585365854 0.490905802052831 0.855578683577791 GO:0004559 alpha-mannosidase activity 1/820 15/18639 0.0666666666666667 1.51536585365854 0.490905802052831 0.855578683577791 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/820 15/18639 0.0666666666666667 1.51536585365854 0.490905802052831 0.855578683577791 GO:0004953 icosanoid receptor activity 1/820 15/18639 0.0666666666666667 1.51536585365854 0.490905802052831 0.855578683577791 GO:0015116 sulfate transmembrane transporter activity 1/820 15/18639 0.0666666666666667 1.51536585365854 0.490905802052831 0.855578683577791 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/820 15/18639 0.0666666666666667 1.51536585365854 0.490905802052831 0.855578683577791 GO:0015929 hexosaminidase activity 1/820 15/18639 0.0666666666666667 1.51536585365854 0.490905802052831 0.855578683577791 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/820 15/18639 0.0666666666666667 1.51536585365854 0.490905802052831 0.855578683577791 GO:0017081 chloride channel regulator activity 1/820 15/18639 0.0666666666666667 1.51536585365854 0.490905802052831 0.855578683577791 GO:0031005 filamin binding 1/820 15/18639 0.0666666666666667 1.51536585365854 0.490905802052831 0.855578683577791 GO:0034483 heparan sulfate sulfotransferase activity 1/820 15/18639 0.0666666666666667 1.51536585365854 0.490905802052831 0.855578683577791 GO:0050780 dopamine receptor binding 1/820 15/18639 0.0666666666666667 1.51536585365854 0.490905802052831 0.855578683577791 GO:0001098 basal transcription machinery binding 3/820 60/18639 0.05 1.1365243902439 0.495294851481281 0.857105984123635 GO:0001099 basal RNA polymerase II transcription machinery binding 3/820 60/18639 0.05 1.1365243902439 0.495294851481281 0.857105984123635 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 3/820 60/18639 0.05 1.1365243902439 0.495294851481281 0.857105984123635 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 3/820 60/18639 0.05 1.1365243902439 0.495294851481281 0.857105984123635 GO:0005525 GTP binding 17/820 378/18639 0.044973544973545 1.0222706155633 0.498246847825297 0.860688360137151 GO:0005501 retinoid binding 2/820 38/18639 0.0526315789473684 1.19634146341463 0.502888709748065 0.862308291907933 GO:0019840 isoprenoid binding 2/820 38/18639 0.0526315789473684 1.19634146341463 0.502888709748065 0.862308291907933 GO:0140996 histone H3 kinase activity 16/820 357/18639 0.0448179271708683 1.01873334699734 0.506079913950371 0.862308291907933 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 3/820 61/18639 0.0491803278688525 1.11789284286285 0.506402772318362 0.862308291907933 GO:0019905 syntaxin binding 3/820 61/18639 0.0491803278688525 1.11789284286285 0.506402772318362 0.862308291907933 GO:0004527 exonuclease activity 4/820 84/18639 0.0476190476190476 1.08240418118467 0.508486650746243 0.862308291907933 GO:0000062 fatty-acyl-CoA binding 1/820 16/18639 0.0625 1.42065548780488 0.513320817211587 0.862308291907933 GO:0004707 MAP kinase activity 1/820 16/18639 0.0625 1.42065548780488 0.513320817211587 0.862308291907933 GO:0005159 insulin-like growth factor receptor binding 1/820 16/18639 0.0625 1.42065548780488 0.513320817211587 0.862308291907933 GO:0015385 sodium:proton antiporter activity 1/820 16/18639 0.0625 1.42065548780488 0.513320817211587 0.862308291907933 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/820 16/18639 0.0625 1.42065548780488 0.513320817211587 0.862308291907933 GO:0016722 oxidoreductase activity, acting on metal ions 1/820 16/18639 0.0625 1.42065548780488 0.513320817211587 0.862308291907933 GO:0030275 LRR domain binding 1/820 16/18639 0.0625 1.42065548780488 0.513320817211587 0.862308291907933 GO:0043023 ribosomal large subunit binding 1/820 16/18639 0.0625 1.42065548780488 0.513320817211587 0.862308291907933 GO:0055102 lipase inhibitor activity 1/820 16/18639 0.0625 1.42065548780488 0.513320817211587 0.862308291907933 GO:0070411 I-SMAD binding 1/820 16/18639 0.0625 1.42065548780488 0.513320817211587 0.862308291907933 GO:0000217 DNA secondary structure binding 2/820 39/18639 0.0512820512820513 1.1656660412758 0.516824030587795 0.864666115113347 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 2/820 39/18639 0.0512820512820513 1.1656660412758 0.516824030587795 0.864666115113347 GO:0015179 L-amino acid transmembrane transporter activity 3/820 62/18639 0.0483870967741935 1.09986231313926 0.517382183633396 0.864666115113347 GO:0035173 histone kinase activity 16/820 360/18639 0.0444444444444444 1.01024390243902 0.519765634772198 0.867164546218231 GO:0050997 quaternary ammonium group binding 2/820 40/18639 0.05 1.1365243902439 0.530497088216136 0.871159685128926 GO:0140662 ATP-dependent protein folding chaperone 2/820 40/18639 0.05 1.1365243902439 0.530497088216136 0.871159685128926 GO:0042578 phosphoric ester hydrolase activity 16/820 363/18639 0.0440771349862259 1.00189477927837 0.533352304009196 0.871159685128926 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/820 17/18639 0.0588235294117647 1.337087517934 0.534750067594796 0.871159685128926 GO:0016018 cyclosporin A binding 1/820 17/18639 0.0588235294117647 1.337087517934 0.534750067594796 0.871159685128926 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/820 17/18639 0.0588235294117647 1.337087517934 0.534750067594796 0.871159685128926 GO:0031489 myosin V binding 1/820 17/18639 0.0588235294117647 1.337087517934 0.534750067594796 0.871159685128926 GO:0036041 long-chain fatty acid binding 1/820 17/18639 0.0588235294117647 1.337087517934 0.534750067594796 0.871159685128926 GO:0045125 bioactive lipid receptor activity 1/820 17/18639 0.0588235294117647 1.337087517934 0.534750067594796 0.871159685128926 GO:0048038 quinone binding 1/820 17/18639 0.0588235294117647 1.337087517934 0.534750067594796 0.871159685128926 GO:0051787 misfolded protein binding 1/820 17/18639 0.0588235294117647 1.337087517934 0.534750067594796 0.871159685128926 GO:0070492 oligosaccharide binding 1/820 17/18639 0.0588235294117647 1.337087517934 0.534750067594796 0.871159685128926 GO:1901567 fatty acid derivative binding 1/820 17/18639 0.0588235294117647 1.337087517934 0.534750067594796 0.871159685128926 GO:1990226 histone methyltransferase binding 1/820 17/18639 0.0588235294117647 1.337087517934 0.534750067594796 0.871159685128926 GO:0016853 isomerase activity 8/820 180/18639 0.0444444444444444 1.01024390243902 0.53919300776844 0.871159685128926 GO:0016877 ligase activity, forming carbon-sulfur bonds 2/820 41/18639 0.0487804878048781 1.10880428316478 0.543903964940389 0.871159685128926 GO:0017080 sodium channel regulator activity 2/820 41/18639 0.0487804878048781 1.10880428316478 0.543903964940389 0.871159685128926 GO:0140318 protein transporter activity 2/820 41/18639 0.0487804878048781 1.10880428316478 0.543903964940389 0.871159685128926 GO:0120013 lipid transfer activity 3/820 65/18639 0.0461538461538462 1.04909943714822 0.549506583021871 0.871159685128926 GO:0160215 deacylase activity 3/820 65/18639 0.0461538461538462 1.04909943714822 0.549506583021871 0.871159685128926 GO:0043022 ribosome binding 5/820 112/18639 0.0446428571428571 1.01475391986063 0.550864155540573 0.871159685128926 GO:0000400 four-way junction DNA binding 1/820 18/18639 0.0555555555555556 1.26280487804878 0.555236854436825 0.871159685128926 GO:0008308 voltage-gated monoatomic anion channel activity 1/820 18/18639 0.0555555555555556 1.26280487804878 0.555236854436825 0.871159685128926 GO:0008409 5'-3' exonuclease activity 1/820 18/18639 0.0555555555555556 1.26280487804878 0.555236854436825 0.871159685128926 GO:0008525 phosphatidylcholine transporter activity 1/820 18/18639 0.0555555555555556 1.26280487804878 0.555236854436825 0.871159685128926 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/820 18/18639 0.0555555555555556 1.26280487804878 0.555236854436825 0.871159685128926 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/820 18/18639 0.0555555555555556 1.26280487804878 0.555236854436825 0.871159685128926 GO:0017075 syntaxin-1 binding 1/820 18/18639 0.0555555555555556 1.26280487804878 0.555236854436825 0.871159685128926 GO:0017128 phospholipid scramblase activity 1/820 18/18639 0.0555555555555556 1.26280487804878 0.555236854436825 0.871159685128926 GO:0032393 MHC class I receptor activity 1/820 18/18639 0.0555555555555556 1.26280487804878 0.555236854436825 0.871159685128926 GO:0034185 apolipoprotein binding 1/820 18/18639 0.0555555555555556 1.26280487804878 0.555236854436825 0.871159685128926 GO:0098641 cadherin binding involved in cell-cell adhesion 1/820 18/18639 0.0555555555555556 1.26280487804878 0.555236854436825 0.871159685128926 GO:1901611 phosphatidylglycerol binding 1/820 18/18639 0.0555555555555556 1.26280487804878 0.555236854436825 0.871159685128926 GO:0016859 cis-trans isomerase activity 2/820 42/18639 0.0476190476190476 1.08240418118467 0.557041593979058 0.871159685128926 GO:0035198 miRNA binding 2/820 42/18639 0.0476190476190476 1.08240418118467 0.557041593979058 0.871159685128926 GO:0008017 microtubule binding 12/820 276/18639 0.0434782608695652 0.988282078472959 0.558435163688135 0.871159685128926 GO:0001217 DNA-binding transcription repressor activity 12/820 278/18639 0.0431654676258993 0.981172135462362 0.568602756365445 0.871159685128926 GO:0016500 protein-hormone receptor activity 3/820 67/18639 0.0447761194029851 1.01778303603932 0.570208418412855 0.871159685128926 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 4/820 91/18639 0.043956043956044 0.999142321093541 0.572083842118869 0.871159685128926 GO:0072341 modified amino acid binding 4/820 91/18639 0.043956043956044 0.999142321093541 0.572083842118869 0.871159685128926 GO:0003756 protein disulfide isomerase activity 1/820 19/18639 0.0526315789473684 1.19634146341463 0.574822579121955 0.871159685128926 GO:0005229 intracellularly calcium-gated chloride channel activity 1/820 19/18639 0.0526315789473684 1.19634146341463 0.574822579121955 0.871159685128926 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/820 19/18639 0.0526315789473684 1.19634146341463 0.574822579121955 0.871159685128926 GO:0005520 insulin-like growth factor binding 1/820 19/18639 0.0526315789473684 1.19634146341463 0.574822579121955 0.871159685128926 GO:0008301 DNA binding, bending 1/820 19/18639 0.0526315789473684 1.19634146341463 0.574822579121955 0.871159685128926 GO:0008381 mechanosensitive monoatomic ion channel activity 1/820 19/18639 0.0526315789473684 1.19634146341463 0.574822579121955 0.871159685128926 GO:0008574 plus-end-directed microtubule motor activity 1/820 19/18639 0.0526315789473684 1.19634146341463 0.574822579121955 0.871159685128926 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/820 19/18639 0.0526315789473684 1.19634146341463 0.574822579121955 0.871159685128926 GO:0022821 solute:potassium antiporter activity 1/820 19/18639 0.0526315789473684 1.19634146341463 0.574822579121955 0.871159685128926 GO:0030506 ankyrin binding 1/820 19/18639 0.0526315789473684 1.19634146341463 0.574822579121955 0.871159685128926 GO:0034987 immunoglobulin receptor binding 1/820 19/18639 0.0526315789473684 1.19634146341463 0.574822579121955 0.871159685128926 GO:0042800 histone H3K4 methyltransferase activity 1/820 19/18639 0.0526315789473684 1.19634146341463 0.574822579121955 0.871159685128926 GO:0042834 peptidoglycan binding 1/820 19/18639 0.0526315789473684 1.19634146341463 0.574822579121955 0.871159685128926 GO:0046624 sphingolipid transporter activity 1/820 19/18639 0.0526315789473684 1.19634146341463 0.574822579121955 0.871159685128926 GO:0050145 nucleoside monophosphate kinase activity 1/820 19/18639 0.0526315789473684 1.19634146341463 0.574822579121955 0.871159685128926 GO:0070003 threonine-type peptidase activity 1/820 19/18639 0.0526315789473684 1.19634146341463 0.574822579121955 0.871159685128926 GO:0097001 ceramide binding 1/820 19/18639 0.0526315789473684 1.19634146341463 0.574822579121955 0.871159685128926 GO:0120227 acyl-CoA binding 1/820 19/18639 0.0526315789473684 1.19634146341463 0.574822579121955 0.871159685128926 GO:0141147 intracellularly calcium-gated channel activity 1/820 19/18639 0.0526315789473684 1.19634146341463 0.574822579121955 0.871159685128926 GO:0030145 manganese ion binding 3/820 68/18639 0.0441176470588235 1.0028156384505 0.5803359791191 0.876447612138981 GO:0043178 alcohol binding 4/820 92/18639 0.0434782608695652 0.988282078472959 0.580787314089596 0.876447612138981 GO:0001046 core promoter sequence-specific DNA binding 2/820 44/18639 0.0454545454545455 1.03320399113082 0.582500697949899 0.876447612138981 GO:0030547 signaling receptor inhibitor activity 2/820 44/18639 0.0454545454545455 1.03320399113082 0.582500697949899 0.876447612138981 GO:0031406 carboxylic acid binding 8/820 187/18639 0.0427807486631016 0.972427285770184 0.582801742088318 0.876447612138981 GO:0001614 purinergic nucleotide receptor activity 1/820 20/18639 0.05 1.1365243902439 0.593546826443115 0.880946946461996 GO:0001972 retinoic acid binding 1/820 20/18639 0.05 1.1365243902439 0.593546826443115 0.880946946461996 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/820 20/18639 0.05 1.1365243902439 0.593546826443115 0.880946946461996 GO:0016502 nucleotide receptor activity 1/820 20/18639 0.05 1.1365243902439 0.593546826443115 0.880946946461996 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/820 20/18639 0.05 1.1365243902439 0.593546826443115 0.880946946461996 GO:0042288 MHC class I protein binding 1/820 20/18639 0.05 1.1365243902439 0.593546826443115 0.880946946461996 GO:0043024 ribosomal small subunit binding 1/820 20/18639 0.05 1.1365243902439 0.593546826443115 0.880946946461996 GO:0052745 inositol phosphate phosphatase activity 1/820 20/18639 0.05 1.1365243902439 0.593546826443115 0.880946946461996 GO:0051539 4 iron, 4 sulfur cluster binding 2/820 45/18639 0.0444444444444444 1.01024390243902 0.594819710777106 0.880946946461996 GO:0140303 intramembrane lipid transporter activity 2/820 45/18639 0.0444444444444444 1.01024390243902 0.594819710777106 0.880946946461996 GO:0016782 transferase activity, transferring sulphur-containing groups 3/820 70/18639 0.0428571428571429 0.974163763066202 0.600132596879991 0.887468809931623 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/820 21/18639 0.0476190476190476 1.08240418118467 0.611447444216177 0.893372313705073 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/820 21/18639 0.0476190476190476 1.08240418118467 0.611447444216177 0.893372313705073 GO:0005123 death receptor binding 1/820 21/18639 0.0476190476190476 1.08240418118467 0.611447444216177 0.893372313705073 GO:0005248 voltage-gated sodium channel activity 1/820 21/18639 0.0476190476190476 1.08240418118467 0.611447444216177 0.893372313705073 GO:0015125 bile acid transmembrane transporter activity 1/820 21/18639 0.0476190476190476 1.08240418118467 0.611447444216177 0.893372313705073 GO:0051010 microtubule plus-end binding 1/820 21/18639 0.0476190476190476 1.08240418118467 0.611447444216177 0.893372313705073 GO:0061891 calcium ion sensor activity 1/820 21/18639 0.0476190476190476 1.08240418118467 0.611447444216177 0.893372313705073 GO:0070182 DNA polymerase binding 1/820 21/18639 0.0476190476190476 1.08240418118467 0.611447444216177 0.893372313705073 GO:0004175 endopeptidase activity 17/820 405/18639 0.0419753086419753 0.954119241192412 0.614156010828562 0.895237520834649 GO:0004896 cytokine receptor activity 4/820 96/18639 0.0416666666666667 0.947103658536585 0.614558544015589 0.895237520834649 GO:0003697 single-stranded DNA binding 5/820 121/18639 0.0413223140495868 0.939276355573473 0.619848645203331 0.901598029386664 GO:0008236 serine-type peptidase activity 8/820 194/18639 0.0412371134020619 0.93733970329394 0.62437252603948 0.902304473278138 GO:0008970 phospholipase A1 activity 1/820 22/18639 0.0454545454545455 1.03320399113082 0.628560619409148 0.902304473278138 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/820 22/18639 0.0454545454545455 1.03320399113082 0.628560619409148 0.902304473278138 GO:0033691 sialic acid binding 1/820 22/18639 0.0454545454545455 1.03320399113082 0.628560619409148 0.902304473278138 GO:0034062 5'-3' RNA polymerase activity 1/820 22/18639 0.0454545454545455 1.03320399113082 0.628560619409148 0.902304473278138 GO:0070034 telomerase RNA binding 1/820 22/18639 0.0454545454545455 1.03320399113082 0.628560619409148 0.902304473278138 GO:0097747 RNA polymerase activity 1/820 22/18639 0.0454545454545455 1.03320399113082 0.628560619409148 0.902304473278138 GO:0140784 metal ion sensor activity 1/820 22/18639 0.0454545454545455 1.03320399113082 0.628560619409148 0.902304473278138 GO:0004521 RNA endonuclease activity 3/820 73/18639 0.0410958904109589 0.934129635816906 0.628654755972473 0.902304473278138 GO:0140693 molecular condensate scaffold activity 2/820 48/18639 0.0416666666666667 0.947103658536585 0.630132590634665 0.903097516093147 GO:0015085 calcium ion transmembrane transporter activity 6/820 147/18639 0.0408163265306122 0.927775012444002 0.631845681190447 0.904224904460229 GO:0016763 pentosyltransferase activity 2/820 49/18639 0.0408163265306122 0.927775012444002 0.641358017856484 0.910915843872808 GO:0035254 glutamate receptor binding 2/820 49/18639 0.0408163265306122 0.927775012444002 0.641358017856484 0.910915843872808 GO:0000295 adenine nucleotide transmembrane transporter activity 1/820 23/18639 0.0434782608695652 0.988282078472959 0.644920950938637 0.910915843872808 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/820 23/18639 0.0434782608695652 0.988282078472959 0.644920950938637 0.910915843872808 GO:0005212 structural constituent of eye lens 1/820 23/18639 0.0434782608695652 0.988282078472959 0.644920950938637 0.910915843872808 GO:0016493 C-C chemokine receptor activity 1/820 23/18639 0.0434782608695652 0.988282078472959 0.644920950938637 0.910915843872808 GO:0042171 lysophosphatidic acid acyltransferase activity 1/820 23/18639 0.0434782608695652 0.988282078472959 0.644920950938637 0.910915843872808 GO:0071617 lysophospholipid acyltransferase activity 1/820 23/18639 0.0434782608695652 0.988282078472959 0.644920950938637 0.910915843872808 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/820 23/18639 0.0434782608695652 0.988282078472959 0.644920950938637 0.910915843872808 GO:0017171 serine hydrolase activity 8/820 198/18639 0.0404040404040404 0.91840354767184 0.64709441919027 0.912664961170091 GO:0003823 antigen binding 7/820 174/18639 0.0402298850574713 0.914444911690496 0.6486542945175 0.913544865005887 GO:0051536 iron-sulfur cluster binding 3/820 76/18639 0.0394736842105263 0.897256097560976 0.655741555101095 0.919697635972361 GO:0004252 serine-type endopeptidase activity 7/820 176/18639 0.0397727272727273 0.904053492239468 0.660398643693027 0.919697635972361 GO:0004622 lysophospholipase activity 1/820 24/18639 0.0416666666666667 0.947103658536585 0.660561519279329 0.919697635972361 GO:0005315 phosphate transmembrane transporter activity 1/820 24/18639 0.0416666666666667 0.947103658536585 0.660561519279329 0.919697635972361 GO:0015295 solute:proton symporter activity 1/820 24/18639 0.0416666666666667 0.947103658536585 0.660561519279329 0.919697635972361 GO:0019957 C-C chemokine binding 1/820 24/18639 0.0416666666666667 0.947103658536585 0.660561519279329 0.919697635972361 GO:0050431 transforming growth factor beta binding 1/820 24/18639 0.0416666666666667 0.947103658536585 0.660561519279329 0.919697635972361 GO:0050699 WW domain binding 1/820 24/18639 0.0416666666666667 0.947103658536585 0.660561519279329 0.919697635972361 GO:0005048 signal sequence binding 2/820 51/18639 0.0392156862745098 0.891391678622669 0.66299979395439 0.921777491309807 GO:0051540 metal cluster binding 3/820 77/18639 0.038961038961039 0.885603420969275 0.664448595284893 0.922477708389837 GO:0005253 monoatomic anion channel activity 4/820 103/18639 0.0388349514563107 0.882737390480701 0.669424399045062 0.925324357941552 GO:0001216 DNA-binding transcription activator activity 20/820 491/18639 0.0407331975560081 0.925885450300531 0.671097183391844 0.925324357941552 GO:0000030 mannosyltransferase activity 1/820 25/18639 0.04 0.909219512195122 0.675513953025821 0.925324357941552 GO:0005251 delayed rectifier potassium channel activity 1/820 25/18639 0.04 0.909219512195122 0.675513953025821 0.925324357941552 GO:0015271 outward rectifier potassium channel activity 1/820 25/18639 0.04 0.909219512195122 0.675513953025821 0.925324357941552 GO:0015645 fatty acid ligase activity 1/820 25/18639 0.04 0.909219512195122 0.675513953025821 0.925324357941552 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/820 25/18639 0.04 0.909219512195122 0.675513953025821 0.925324357941552 GO:0047617 fatty acyl-CoA hydrolase activity 1/820 25/18639 0.04 0.909219512195122 0.675513953025821 0.925324357941552 GO:0120515 fatty acid-CoA ligase activity 1/820 25/18639 0.04 0.909219512195122 0.675513953025821 0.925324357941552 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 5/820 130/18639 0.0384615384615385 0.874249530956848 0.682140384943026 0.925324357941552 GO:0004864 protein phosphatase inhibitor activity 2/820 53/18639 0.0377358490566038 0.857754256787851 0.683578037598559 0.925324357941552 GO:0005262 calcium channel activity 5/820 131/18639 0.0381679389312977 0.867575870415193 0.688619522093487 0.925324357941552 GO:0001637 G protein-coupled chemoattractant receptor activity 1/820 26/18639 0.0384615384615385 0.874249530956848 0.689808492540102 0.925324357941552 GO:0004529 DNA exonuclease activity 1/820 26/18639 0.0384615384615385 0.874249530956848 0.689808492540102 0.925324357941552 GO:0004950 chemokine receptor activity 1/820 26/18639 0.0384615384615385 0.874249530956848 0.689808492540102 0.925324357941552 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/820 26/18639 0.0384615384615385 0.874249530956848 0.689808492540102 0.925324357941552 GO:0008143 poly(A) binding 1/820 26/18639 0.0384615384615385 0.874249530956848 0.689808492540102 0.925324357941552 GO:0008157 protein phosphatase 1 binding 1/820 26/18639 0.0384615384615385 0.874249530956848 0.689808492540102 0.925324357941552 GO:0015216 purine nucleotide transmembrane transporter activity 1/820 26/18639 0.0384615384615385 0.874249530956848 0.689808492540102 0.925324357941552 GO:0016289 acyl-CoA hydrolase activity 1/820 26/18639 0.0384615384615385 0.874249530956848 0.689808492540102 0.925324357941552 GO:0051139 metal cation:proton antiporter activity 1/820 26/18639 0.0384615384615385 0.874249530956848 0.689808492540102 0.925324357941552 GO:0070006 metalloaminopeptidase activity 1/820 26/18639 0.0384615384615385 0.874249530956848 0.689808492540102 0.925324357941552 GO:0097602 cullin family protein binding 1/820 26/18639 0.0384615384615385 0.874249530956848 0.689808492540102 0.925324357941552 GO:0120014 phospholipid transfer activity 1/820 26/18639 0.0384615384615385 0.874249530956848 0.689808492540102 0.925324357941552 GO:0000149 SNARE binding 4/820 106/18639 0.0377358490566038 0.857754256787851 0.691226384526471 0.925324357941552 GO:0015485 cholesterol binding 2/820 54/18639 0.037037037037037 0.841869918699187 0.693475214438153 0.925324357941552 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/820 54/18639 0.037037037037037 0.841869918699187 0.693475214438153 0.925324357941552 GO:0050661 NADP binding 2/820 54/18639 0.037037037037037 0.841869918699187 0.693475214438153 0.925324357941552 GO:0003713 transcription coactivator activity 10/820 256/18639 0.0390625 0.887909679878049 0.694153506085661 0.925324357941552 GO:0005179 hormone activity 5/820 132/18639 0.0378787878787879 0.86100332594235 0.695008431567836 0.925324357941552 GO:0141003 histone H2AX kinase activity 14/820 354/18639 0.0395480225988701 0.898945845390657 0.696698896532796 0.925324357941552 GO:0098632 cell-cell adhesion mediator activity 2/820 55/18639 0.0363636363636364 0.826563192904656 0.703115297086556 0.925324357941552 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/820 27/18639 0.037037037037037 0.841869918699187 0.703474050812123 0.925324357941552 GO:0008266 poly(U) RNA binding 1/820 27/18639 0.037037037037037 0.841869918699187 0.703474050812123 0.925324357941552 GO:0008320 protein transmembrane transporter activity 1/820 27/18639 0.037037037037037 0.841869918699187 0.703474050812123 0.925324357941552 GO:0016405 CoA-ligase activity 1/820 27/18639 0.037037037037037 0.841869918699187 0.703474050812123 0.925324357941552 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/820 27/18639 0.037037037037037 0.841869918699187 0.703474050812123 0.925324357941552 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/820 27/18639 0.037037037037037 0.841869918699187 0.703474050812123 0.925324357941552 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/820 27/18639 0.037037037037037 0.841869918699187 0.703474050812123 0.925324357941552 GO:0019212 phosphatase inhibitor activity 2/820 56/18639 0.0357142857142857 0.811803135888502 0.712501720651065 0.933700070942078 GO:0005254 chloride channel activity 3/820 83/18639 0.036144578313253 0.821583896561857 0.713313753664693 0.933700070942078 GO:0019789 SUMO transferase activity 1/820 28/18639 0.0357142857142857 0.811803135888502 0.716538271655345 0.933700070942078 GO:0051393 alpha-actinin binding 1/820 28/18639 0.0357142857142857 0.811803135888502 0.716538271655345 0.933700070942078 GO:0051537 2 iron, 2 sulfur cluster binding 1/820 28/18639 0.0357142857142857 0.811803135888502 0.716538271655345 0.933700070942078 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/820 28/18639 0.0357142857142857 0.811803135888502 0.716538271655345 0.933700070942078 GO:0141052 histone H3 demethylase activity 1/820 28/18639 0.0357142857142857 0.811803135888502 0.716538271655345 0.933700070942078 GO:0140789 histone phosphatase activity 5/820 136/18639 0.0367647058823529 0.835679698708752 0.719657582731982 0.936514400995219 GO:0046943 carboxylic acid transmembrane transporter activity 7/820 188/18639 0.0372340425531915 0.846347950181629 0.725692611849603 0.942121106823206 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 19/820 484/18639 0.0392561983471074 0.892312537794799 0.728168302412337 0.942121106823206 GO:0004181 metallocarboxypeptidase activity 1/820 29/18639 0.0344827586206897 0.783809924306139 0.729027585353836 0.942121106823206 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/820 29/18639 0.0344827586206897 0.783809924306139 0.729027585353836 0.942121106823206 GO:0097472 cyclin-dependent protein kinase activity 1/820 29/18639 0.0344827586206897 0.783809924306139 0.729027585353836 0.942121106823206 GO:0061980 regulatory RNA binding 2/820 58/18639 0.0344827586206897 0.783809924306139 0.730528284527532 0.942121106823206 GO:0005342 organic acid transmembrane transporter activity 7/820 189/18639 0.037037037037037 0.841869918699187 0.730723030599557 0.942121106823206 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/820 30/18639 0.0333333333333333 0.757682926829268 0.740967261872367 0.945338624297294 GO:0008187 poly-pyrimidine tract binding 1/820 30/18639 0.0333333333333333 0.757682926829268 0.740967261872367 0.945338624297294 GO:0015215 nucleotide transmembrane transporter activity 1/820 30/18639 0.0333333333333333 0.757682926829268 0.740967261872367 0.945338624297294 GO:0016769 transferase activity, transferring nitrogenous groups 1/820 30/18639 0.0333333333333333 0.757682926829268 0.740967261872367 0.945338624297294 GO:0031624 ubiquitin conjugating enzyme binding 1/820 30/18639 0.0333333333333333 0.757682926829268 0.740967261872367 0.945338624297294 GO:0032452 histone demethylase activity 1/820 30/18639 0.0333333333333333 0.757682926829268 0.740967261872367 0.945338624297294 GO:0048019 receptor antagonist activity 1/820 30/18639 0.0333333333333333 0.757682926829268 0.740967261872367 0.945338624297294 GO:0070566 adenylyltransferase activity 1/820 30/18639 0.0333333333333333 0.757682926829268 0.740967261872367 0.945338624297294 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/820 60/18639 0.0333333333333333 0.757682926829268 0.747585879882416 0.952537622408927 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/820 31/18639 0.032258064516129 0.73324154209284 0.752381461736124 0.953667930720074 GO:0016411 acylglycerol O-acyltransferase activity 1/820 31/18639 0.032258064516129 0.73324154209284 0.752381461736124 0.953667930720074 GO:0016878 acid-thiol ligase activity 1/820 31/18639 0.032258064516129 0.73324154209284 0.752381461736124 0.953667930720074 GO:0140457 protein demethylase activity 1/820 31/18639 0.032258064516129 0.73324154209284 0.752381461736124 0.953667930720074 GO:0022884 macromolecule transmembrane transporter activity 1/820 32/18639 0.03125 0.710327743902439 0.763293284681974 0.961257091418848 GO:0030515 snoRNA binding 1/820 32/18639 0.03125 0.710327743902439 0.763293284681974 0.961257091418848 GO:0031369 translation initiation factor binding 1/820 32/18639 0.03125 0.710327743902439 0.763293284681974 0.961257091418848 GO:0051059 NF-kappaB binding 1/820 32/18639 0.03125 0.710327743902439 0.763293284681974 0.961257091418848 GO:0070717 poly-purine tract binding 1/820 32/18639 0.03125 0.710327743902439 0.763293284681974 0.961257091418848 GO:0140104 molecular carrier activity 9/820 249/18639 0.036144578313253 0.821583896561857 0.77169341835518 0.969390783813189 GO:0030296 protein tyrosine kinase activator activity 1/820 33/18639 0.0303030303030303 0.68880266075388 0.773724816178765 0.969390783813189 GO:0071889 14-3-3 protein binding 1/820 33/18639 0.0303030303030303 0.68880266075388 0.773724816178765 0.969390783813189 GO:0140416 transcription regulator inhibitor activity 1/820 33/18639 0.0303030303030303 0.68880266075388 0.773724816178765 0.969390783813189 GO:0008376 acetylgalactosaminyltransferase activity 1/820 34/18639 0.0294117647058824 0.668543758967001 0.783697171909895 0.97569823583107 GO:0015020 glucuronosyltransferase activity 1/820 34/18639 0.0294117647058824 0.668543758967001 0.783697171909895 0.97569823583107 GO:0015035 protein-disulfide reductase activity 1/820 34/18639 0.0294117647058824 0.668543758967001 0.783697171909895 0.97569823583107 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/820 34/18639 0.0294117647058824 0.668543758967001 0.783697171909895 0.97569823583107 GO:0004540 RNA nuclease activity 4/820 121/18639 0.0330578512396694 0.751421084458778 0.784757290089539 0.97569823583107 GO:0015108 chloride transmembrane transporter activity 4/820 121/18639 0.0330578512396694 0.751421084458778 0.784757290089539 0.97569823583107 GO:0022832 voltage-gated channel activity 6/820 175/18639 0.0342857142857143 0.779331010452962 0.78707953566969 0.977340492129284 GO:0008509 monoatomic anion transmembrane transporter activity 5/820 149/18639 0.0335570469798658 0.762768047143559 0.789804264361734 0.978602357282196 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/820 122/18639 0.0327868852459016 0.745261895241903 0.790101083543412 0.978602357282196 GO:0000175 3'-5'-RNA exonuclease activity 1/820 35/18639 0.0285714285714286 0.649442508710801 0.793230540307309 0.981233215893452 GO:0016407 acetyltransferase activity 3/820 96/18639 0.03125 0.710327743902439 0.800076637052141 0.983582579861321 GO:0042054 histone methyltransferase activity 2/820 67/18639 0.0298507462686567 0.67852202402621 0.800146141440226 0.983582579861321 GO:0000993 RNA polymerase II complex binding 1/820 36/18639 0.0277777777777778 0.63140243902439 0.802344223222166 0.983582579861321 GO:0004033 aldo-keto reductase (NADPH) activity 1/820 36/18639 0.0277777777777778 0.63140243902439 0.802344223222166 0.983582579861321 GO:0004190 aspartic-type endopeptidase activity 1/820 36/18639 0.0277777777777778 0.63140243902439 0.802344223222166 0.983582579861321 GO:0005484 SNAP receptor activity 1/820 36/18639 0.0277777777777778 0.63140243902439 0.802344223222166 0.983582579861321 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/820 36/18639 0.0277777777777778 0.63140243902439 0.802344223222166 0.983582579861321 GO:0005548 phospholipid transporter activity 2/820 68/18639 0.0294117647058824 0.668543758967001 0.806807055449957 0.983582579861321 GO:0032934 sterol binding 2/820 68/18639 0.0294117647058824 0.668543758967001 0.806807055449957 0.983582579861321 GO:1990841 promoter-specific chromatin binding 2/820 68/18639 0.0294117647058824 0.668543758967001 0.806807055449957 0.983582579861321 GO:0003774 cytoskeletal motor activity 5/820 153/18639 0.0326797385620915 0.742826398852224 0.808408497181014 0.983582579861321 GO:0022829 wide pore channel activity 1/820 37/18639 0.027027027027027 0.614337508239947 0.811056674813728 0.983582579861321 GO:0070001 aspartic-type peptidase activity 1/820 37/18639 0.027027027027027 0.614337508239947 0.811056674813728 0.983582579861321 GO:0008170 N-methyltransferase activity 3/820 98/18639 0.0306122448979592 0.695831259333001 0.811260998119094 0.983582579861321 GO:0005506 iron ion binding 5/820 154/18639 0.0324675324675325 0.738002850807729 0.812849342506925 0.983582579861321 GO:0002039 p53 binding 2/820 69/18639 0.0289855072463768 0.658854718981972 0.813269612651727 0.983582579861321 GO:0008080 N-acetyltransferase activity 2/820 69/18639 0.0289855072463768 0.658854718981972 0.813269612651727 0.983582579861321 GO:0016279 protein-lysine N-methyltransferase activity 2/820 69/18639 0.0289855072463768 0.658854718981972 0.813269612651727 0.983582579861321 GO:0004518 nuclease activity 7/820 209/18639 0.0334928229665072 0.761308203991131 0.818004462282741 0.986275496976432 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/820 38/18639 0.0263157894736842 0.598170731707317 0.819385538734422 0.986275496976432 GO:0042887 amide transmembrane transporter activity 1/820 38/18639 0.0263157894736842 0.598170731707317 0.819385538734422 0.986275496976432 GO:0016278 lysine N-methyltransferase activity 2/820 70/18639 0.0285714285714286 0.649442508710801 0.81953834840972 0.986275496976432 GO:0015171 amino acid transmembrane transporter activity 3/820 102/18639 0.0294117647058824 0.668543758967001 0.832045792147818 0.995018578409843 GO:0004177 aminopeptidase activity 1/820 40/18639 0.025 0.568262195121951 0.834959237415636 0.995018578409843 GO:0004532 RNA exonuclease activity 1/820 40/18639 0.025 0.568262195121951 0.834959237415636 0.995018578409843 GO:0015036 disulfide oxidoreductase activity 1/820 40/18639 0.025 0.568262195121951 0.834959237415636 0.995018578409843 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 1/820 40/18639 0.025 0.568262195121951 0.834959237415636 0.995018578409843 GO:0032451 demethylase activity 1/820 40/18639 0.025 0.568262195121951 0.834959237415636 0.995018578409843 GO:0061791 GTPase motor activity 1/820 40/18639 0.025 0.568262195121951 0.834959237415636 0.995018578409843 GO:1990606 membrane scission GTPase motor activity 1/820 40/18639 0.025 0.568262195121951 0.834959237415636 0.995018578409843 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 4/820 132/18639 0.0303030303030303 0.68880266075388 0.837857518266124 0.996929965211609 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 9/820 268/18639 0.0335820895522388 0.763337277029487 0.838606046556077 0.996929965211609 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/820 41/18639 0.024390243902439 0.554402141582391 0.842235619227517 0.998811621343933 GO:0140828 metal cation:monoatomic cation antiporter activity 1/820 41/18639 0.024390243902439 0.554402141582391 0.842235619227517 0.998811621343933 GO:0031492 nucleosomal DNA binding 1/820 42/18639 0.0238095238095238 0.541202090592334 0.849191571062846 0.999814563001473 GO:0043175 RNA polymerase core enzyme binding 1/820 42/18639 0.0238095238095238 0.541202090592334 0.849191571062846 0.999814563001473 GO:0015297 antiporter activity 4/820 135/18639 0.0296296296296296 0.67349593495935 0.850281364330792 0.999814563001473 GO:0003724 RNA helicase activity 2/820 77/18639 0.025974025974026 0.590402280646183 0.858368643544631 0.999814563001473 GO:0005496 steroid binding 3/820 108/18639 0.0277777777777778 0.63140243902439 0.859521284764754 0.999814563001473 GO:0016790 thiolester hydrolase activity 1/820 44/18639 0.0227272727272727 0.51660199556541 0.862197942787385 0.999814563001473 GO:0008186 ATP-dependent activity, acting on RNA 2/820 79/18639 0.0253164556962025 0.575455387465267 0.867970756768906 0.999814563001473 GO:0046915 transition metal ion transmembrane transporter activity 1/820 45/18639 0.0222222222222222 0.505121951219512 0.868274720787619 0.999814563001473 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 1/820 46/18639 0.0217391304347826 0.494141039236479 0.874083838188616 0.999814563001473 GO:0015101 organic cation transmembrane transporter activity 2/820 81/18639 0.0246913580246914 0.561246612466125 0.876971597165243 0.999814563001473 GO:0022843 voltage-gated monoatomic cation channel activity 4/820 143/18639 0.027972027972028 0.635817840695889 0.879527243665601 0.999814563001473 GO:0061733 protein-lysine-acetyltransferase activity 1/820 47/18639 0.0212765957446809 0.483627400103788 0.879637070732334 0.999814563001473 GO:0099095 ligand-gated monoatomic anion channel activity 1/820 47/18639 0.0212765957446809 0.483627400103788 0.879637070732334 0.999814563001473 GO:0140938 histone H3 methyltransferase activity 1/820 47/18639 0.0212765957446809 0.483627400103788 0.879637070732334 0.999814563001473 GO:0016887 ATP hydrolysis activity 14/820 417/18639 0.0335731414868106 0.763133883137392 0.8824043391333 0.999814563001473 GO:0005244 voltage-gated monoatomic ion channel activity 5/820 173/18639 0.0289017341040462 0.656950514591851 0.882520812185693 0.999814563001473 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/820 48/18639 0.0208333333333333 0.473551829268293 0.884945676691859 0.999814563001473 GO:0004721 phosphoprotein phosphatase activity 5/820 175/18639 0.0285714285714286 0.649442508710801 0.88837304658086 0.999814563001473 GO:0015605 organophosphate ester transmembrane transporter activity 1/820 50/18639 0.02 0.454609756097561 0.8948715898877 0.999814563001473 GO:0050660 flavin adenine dinucleotide binding 2/820 86/18639 0.0232558139534884 0.52861599546228 0.897051925489758 0.999814563001473 GO:0022836 gated channel activity 10/820 318/18639 0.0314465408805031 0.714795213989876 0.897393747202477 0.999814563001473 GO:0005272 sodium channel activity 1/820 51/18639 0.0196078431372549 0.445695839311334 0.899509025806366 0.999814563001473 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/820 52/18639 0.0192307692307692 0.437124765478424 0.903942133125001 0.999814563001473 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 5/820 181/18639 0.0276243093922652 0.627914027759062 0.904448780613131 0.999814563001473 GO:0005544 calcium-dependent phospholipid binding 1/820 53/18639 0.0188679245283019 0.428877128393925 0.908179904192817 0.999814563001473 GO:0017046 peptide hormone binding 1/820 53/18639 0.0188679245283019 0.428877128393925 0.908179904192817 0.999814563001473 GO:0034212 protein N-acetyltransferase activity 1/820 53/18639 0.0188679245283019 0.428877128393925 0.908179904192817 0.999814563001473 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/820 53/18639 0.0188679245283019 0.428877128393925 0.908179904192817 0.999814563001473 GO:0008514 organic anion transmembrane transporter activity 8/820 269/18639 0.0297397769516729 0.675999637319793 0.909621979968514 0.999814563001473 GO:0061630 ubiquitin protein ligase activity 11/820 353/18639 0.0311614730878187 0.708315484004698 0.912149305609611 0.999814563001473 GO:0008374 O-acyltransferase activity 1/820 55/18639 0.0181818181818182 0.413281596452328 0.916103447908099 0.999814563001473 GO:0052689 carboxylic ester hydrolase activity 2/820 92/18639 0.0217391304347826 0.494141039236479 0.917112366416271 0.999814563001473 GO:0030170 pyridoxal phosphate binding 1/820 56/18639 0.0178571428571429 0.405901567944251 0.919805297494591 0.999814563001473 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/820 56/18639 0.0178571428571429 0.405901567944251 0.919805297494591 0.999814563001473 GO:0035403 histone H3T6 kinase activity 7/820 247/18639 0.0283400809716599 0.644183864915572 0.921804531107106 0.999814563001473 GO:0004519 endonuclease activity 3/820 127/18639 0.0236220472440945 0.536940656808143 0.922195685063128 0.999814563001473 GO:0019783 ubiquitin-like protein peptidase activity 3/820 127/18639 0.0236220472440945 0.536940656808143 0.922195685063128 0.999814563001473 GO:0016410 N-acyltransferase activity 2/820 94/18639 0.0212765957446809 0.483627400103788 0.922939849676089 0.999814563001473 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/820 57/18639 0.0175438596491228 0.398780487804878 0.923343997169263 0.999814563001473 GO:0070279 vitamin B6 binding 1/820 57/18639 0.0175438596491228 0.398780487804878 0.923343997169263 0.999814563001473 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 3/820 128/18639 0.0234375 0.532745807926829 0.924649303062329 0.999814563001473 GO:0106310 protein serine kinase activity 11/820 361/18639 0.0304709141274238 0.692618741976893 0.925105296357877 0.999814563001473 GO:0015079 potassium ion transmembrane transporter activity 4/820 160/18639 0.025 0.568262195121951 0.925654459742632 0.999814563001473 GO:0008276 protein methyltransferase activity 2/820 95/18639 0.0210526315789474 0.478536585365854 0.925706745440204 0.999814563001473 GO:0008408 3'-5' exonuclease activity 1/820 58/18639 0.0172413793103448 0.39190496215307 0.926726728969995 0.999814563001473 GO:0015459 potassium channel regulator activity 1/820 59/18639 0.0169491525423729 0.385262505167425 0.929960359143 0.999814563001473 GO:0031593 polyubiquitin modification-dependent protein binding 1/820 59/18639 0.0169491525423729 0.385262505167425 0.929960359143 0.999814563001473 GO:0036002 pre-mRNA binding 1/820 59/18639 0.0169491525423729 0.385262505167425 0.929960359143 0.999814563001473 GO:0030594 neurotransmitter receptor activity 2/820 97/18639 0.0206185567010309 0.46866985164697 0.930961687896438 0.999814563001473 GO:0015103 inorganic anion transmembrane transporter activity 4/820 165/18639 0.0242424242424242 0.551042128603104 0.935808703801636 0.999814563001473 GO:0016836 hydro-lyase activity 1/820 61/18639 0.0163934426229508 0.372630947620952 0.936006283237955 0.999814563001473 GO:0043130 ubiquitin binding 2/820 100/18639 0.02 0.454609756097561 0.938189321819312 0.999814563001473 GO:0015291 secondary active transmembrane transporter activity 8/820 287/18639 0.0278745644599303 0.633602447522733 0.940039847363772 0.999814563001473 GO:0061659 ubiquitin-like protein ligase activity 11/820 372/18639 0.0295698924731183 0.67213808025177 0.940238356219324 0.999814563001473 GO:1901682 sulfur compound transmembrane transporter activity 1/820 63/18639 0.0158730158730159 0.360801393728223 0.941530895614865 0.999814563001473 GO:0016779 nucleotidyltransferase activity 3/820 136/18639 0.0220588235294118 0.501407819225251 0.941864593838605 0.999814563001473 GO:0099094 ligand-gated monoatomic cation channel activity 3/820 136/18639 0.0220588235294118 0.501407819225251 0.941864593838605 0.999814563001473 GO:0000287 magnesium ion binding 6/820 230/18639 0.0260869565217391 0.592969247083775 0.942377560520982 0.999814563001473 GO:0004536 DNA nuclease activity 1/820 64/18639 0.015625 0.35516387195122 0.944111896131436 0.999814563001473 GO:0004674 protein serine/threonine kinase activity 13/820 433/18639 0.0300230946882217 0.682439587675322 0.946664628984538 0.999814563001473 GO:0140030 modification-dependent protein binding 4/820 173/18639 0.023121387283237 0.525560411673481 0.949463096480346 0.999814563001473 GO:0003777 microtubule motor activity 1/820 68/18639 0.0147058823529412 0.334271879483501 0.953346920888394 0.999814563001473 GO:0140223 general transcription initiation factor activity 1/820 68/18639 0.0147058823529412 0.334271879483501 0.953346920888394 0.999814563001473 GO:0098960 postsynaptic neurotransmitter receptor activity 1/820 69/18639 0.0144927536231884 0.329427359490986 0.955406881303639 0.999814563001473 GO:0016791 phosphatase activity 7/820 273/18639 0.0256410256410256 0.582833020637899 0.958849742533552 0.999814563001473 GO:0003684 damaged DNA binding 1/820 74/18639 0.0135135135135135 0.307168754119974 0.964421362797599 0.999814563001473 GO:0031491 nucleosome binding 1/820 74/18639 0.0135135135135135 0.307168754119974 0.964421362797599 0.999814563001473 GO:0000510 H3-H4 histone complex chaperone activity 3/820 151/18639 0.0198675496688742 0.451599095461153 0.964724072555064 0.999814563001473 GO:0140584 chromatin extrusion motor activity 3/820 151/18639 0.0198675496688742 0.451599095461153 0.964724072555064 0.999814563001473 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 3/820 151/18639 0.0198675496688742 0.451599095461153 0.964724072555064 0.999814563001473 GO:0140849 ATP-dependent H2AZ histone chaperone activity 3/820 151/18639 0.0198675496688742 0.451599095461153 0.964724072555064 0.999814563001473 GO:0015616 DNA translocase activity 3/820 152/18639 0.0197368421052632 0.448628048780488 0.965898724085706 0.999814563001473 GO:0140674 ATP-dependent histone chaperone activity 3/820 152/18639 0.0197368421052632 0.448628048780488 0.965898724085706 0.999814563001473 GO:0015276 ligand-gated monoatomic ion channel activity 4/820 186/18639 0.021505376344086 0.48882769472856 0.966084021133377 0.999814563001473 GO:0061775 cohesin loader activity 3/820 153/18639 0.0196078431372549 0.445695839311334 0.967036433851868 0.999814563001473 GO:0022834 ligand-gated channel activity 4/820 188/18639 0.0212765957446809 0.483627400103788 0.968135734942084 0.999814563001473 GO:0140597 protein carrier chaperone 4/820 188/18639 0.0212765957446809 0.483627400103788 0.968135734942084 0.999814563001473 GO:0004386 helicase activity 3/820 155/18639 0.0193548387096774 0.439944925255704 0.969205254153699 0.999814563001473 GO:0032182 ubiquitin-like protein binding 2/820 120/18639 0.0166666666666667 0.378841463414634 0.97086226057362 0.999814563001473 GO:0016835 carbon-oxygen lyase activity 1/820 79/18639 0.0126582278481013 0.287727693732634 0.971615336651727 0.999814563001473 GO:0140658 ATP-dependent chromatin remodeler activity 3/820 158/18639 0.0189873417721519 0.43159154059895 0.97220716097173 0.999814563001473 GO:0000049 tRNA binding 1/820 80/18639 0.0125 0.284131097560976 0.972869400441899 0.999814563001473 GO:0016755 aminoacyltransferase activity 14/820 496/18639 0.0282258064516129 0.641586349331235 0.973987185567957 0.999814563001473 GO:0003689 DNA clamp loader activity 3/820 160/18639 0.01875 0.426196646341463 0.974052104392776 0.999814563001473 GO:0033192 calmodulin-dependent protein phosphatase activity 1/820 81/18639 0.0123456790123457 0.280623306233062 0.974068122982857 0.999814563001473 GO:0140791 histone H2AXS140 phosphatase activity 1/820 81/18639 0.0123456790123457 0.280623306233062 0.974068122982857 0.999814563001473 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/820 81/18639 0.0123456790123457 0.280623306233062 0.974068122982857 0.999814563001473 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/820 81/18639 0.0123456790123457 0.280623306233062 0.974068122982857 0.999814563001473 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/820 81/18639 0.0123456790123457 0.280623306233062 0.974068122982857 0.999814563001473 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/820 81/18639 0.0123456790123457 0.280623306233062 0.974068122982857 0.999814563001473 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/820 81/18639 0.0123456790123457 0.280623306233062 0.974068122982857 0.999814563001473 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/820 81/18639 0.0123456790123457 0.280623306233062 0.974068122982857 0.999814563001473 GO:0005267 potassium channel activity 2/820 124/18639 0.0161290322580645 0.36662077104642 0.974999016975699 0.999814563001473 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/820 82/18639 0.0121951219512195 0.277201070791196 0.975213943607604 0.999814563001473 GO:0033549 MAP kinase phosphatase activity 1/820 82/18639 0.0121951219512195 0.277201070791196 0.975213943607604 0.999814563001473 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/820 83/18639 0.0120481927710843 0.273861298853952 0.976309194253816 0.999814563001473 GO:0017018 myosin phosphatase activity 1/820 84/18639 0.0119047619047619 0.270601045296167 0.977356104186553 0.999814563001473 GO:0015081 sodium ion transmembrane transporter activity 3/820 164/18639 0.0182926829268293 0.415801606186794 0.977399065866632 0.999814563001473 GO:0140713 histone chaperone activity 3/820 164/18639 0.0182926829268293 0.415801606186794 0.977399065866632 0.999814563001473 GO:0016757 glycosyltransferase activity 6/820 267/18639 0.0224719101123595 0.510797478761304 0.979008045485684 0.999814563001473 GO:0004842 ubiquitin-protein transferase activity 12/820 449/18639 0.0267260579064588 0.607496333315226 0.979261504199841 0.999814563001473 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 3/820 167/18639 0.0179640718562874 0.408332116255294 0.979635313019481 0.999814563001473 GO:0046873 metal ion transmembrane transporter activity 12/820 450/18639 0.0266666666666667 0.606146341463415 0.979727647905134 0.999814563001473 GO:0019787 ubiquitin-like protein transferase activity 13/820 479/18639 0.0271398747390397 0.616902591781659 0.979738682008688 0.999814563001473 GO:0003727 single-stranded RNA binding 1/820 89/18639 0.0112359550561798 0.255398739380652 0.981936932915694 0.999814563001473 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 5/820 243/18639 0.0205761316872428 0.467705510388437 0.983708626536469 0.999814563001473 GO:0004676 3-phosphoinositide-dependent protein kinase activity 5/820 245/18639 0.0204081632653061 0.463887506222001 0.984675835476367 0.999814563001473 GO:0004711 ribosomal protein S6 kinase activity 5/820 245/18639 0.0204081632653061 0.463887506222001 0.984675835476367 0.999814563001473 GO:0035175 histone H3S10 kinase activity 5/820 245/18639 0.0204081632653061 0.463887506222001 0.984675835476367 0.999814563001473 GO:0035979 histone H2AXS139 kinase activity 5/820 245/18639 0.0204081632653061 0.463887506222001 0.984675835476367 0.999814563001473 GO:0044022 histone H3S28 kinase activity 5/820 245/18639 0.0204081632653061 0.463887506222001 0.984675835476367 0.999814563001473 GO:0044023 histone H4S1 kinase activity 5/820 245/18639 0.0204081632653061 0.463887506222001 0.984675835476367 0.999814563001473 GO:0044024 histone H2AS1 kinase activity 5/820 245/18639 0.0204081632653061 0.463887506222001 0.984675835476367 0.999814563001473 GO:0044025 histone H2BS14 kinase activity 5/820 245/18639 0.0204081632653061 0.463887506222001 0.984675835476367 0.999814563001473 GO:0072354 histone H3T3 kinase activity 5/820 245/18639 0.0204081632653061 0.463887506222001 0.984675835476367 0.999814563001473 GO:0072371 histone H2AS121 kinase activity 5/820 245/18639 0.0204081632653061 0.463887506222001 0.984675835476367 0.999814563001473 GO:0072518 Rho-dependent protein serine/threonine kinase activity 5/820 245/18639 0.0204081632653061 0.463887506222001 0.984675835476367 0.999814563001473 GO:0140823 histone H2BS36 kinase activity 5/820 245/18639 0.0204081632653061 0.463887506222001 0.984675835476367 0.999814563001473 GO:0140855 histone H3S57 kinase activity 5/820 245/18639 0.0204081632653061 0.463887506222001 0.984675835476367 0.999814563001473 GO:0140995 histone H2A kinase activity 5/820 245/18639 0.0204081632653061 0.463887506222001 0.984675835476367 0.999814563001473 GO:0140997 histone H4 kinase activity 5/820 245/18639 0.0204081632653061 0.463887506222001 0.984675835476367 0.999814563001473 GO:0140998 histone H2B kinase activity 5/820 245/18639 0.0204081632653061 0.463887506222001 0.984675835476367 0.999814563001473 GO:1990244 histone H2AT120 kinase activity 5/820 245/18639 0.0204081632653061 0.463887506222001 0.984675835476367 0.999814563001473 GO:0004677 DNA-dependent protein kinase activity 5/820 246/18639 0.0203252032520325 0.462001784651993 0.985138920969365 0.999814563001473 GO:0140857 histone H3T45 kinase activity 5/820 246/18639 0.0203252032520325 0.462001784651993 0.985138920969365 0.999814563001473 GO:0035402 histone H3T11 kinase activity 5/820 247/18639 0.0202429149797571 0.460131332082552 0.985588802129642 0.999814563001473 GO:0042393 histone binding 5/820 247/18639 0.0202429149797571 0.460131332082552 0.985588802129642 0.999814563001473 GO:0042562 hormone binding 1/820 94/18639 0.0106382978723404 0.241813700051894 0.985591964383671 0.999814563001473 GO:0004679 AMP-activated protein kinase activity 5/820 248/18639 0.0201612903225806 0.458275963808025 0.986025825116261 0.999814563001473 GO:0016741 transferase activity, transferring one-carbon groups 4/820 215/18639 0.0186046511627907 0.422892796369824 0.986606002272899 0.999814563001473 GO:0005249 voltage-gated potassium channel activity 1/820 98/18639 0.0102040816326531 0.231943753111 0.987976361871416 0.999814563001473 GO:0004722 protein serine/threonine phosphatase activity 1/820 103/18639 0.00970873786407767 0.220684347620175 0.990410401711005 0.999814563001473 GO:0019842 vitamin binding 2/820 150/18639 0.0133333333333333 0.303073170731707 0.990921279984553 0.999814563001473 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 4/820 229/18639 0.0174672489082969 0.397039088294813 0.991589112323153 0.999814563001473 GO:0004497 monooxygenase activity 1/820 106/18639 0.00943396226415094 0.214438564196963 0.991627674324771 0.999814563001473 GO:0004843 cysteine-type deubiquitinase activity 1/820 108/18639 0.00925925925925926 0.210467479674797 0.992352177099058 0.999814563001473 GO:0101005 deubiquitinase activity 1/820 115/18639 0.00869565217391304 0.197656415694592 0.994429109532162 0.999814563001473 GO:0008168 methyltransferase activity 3/820 204/18639 0.0147058823529412 0.334271879483501 0.994575328805004 0.999814563001473 GO:0015294 solute:monoatomic cation symporter activity 1/820 116/18639 0.00862068965517241 0.195952481076535 0.994675715566692 0.999814563001473 GO:0008094 ATP-dependent activity, acting on DNA 3/820 210/18639 0.0142857142857143 0.324721254355401 0.995647813439558 0.999814563001473 GO:0140098 catalytic activity, acting on RNA 8/820 387/18639 0.020671834625323 0.46988088485536 0.995665675677195 0.999814563001473 GO:0008528 G protein-coupled peptide receptor activity 1/820 122/18639 0.00819672131147541 0.186315473810476 0.995942502972251 0.999814563001473 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 1/820 122/18639 0.00819672131147541 0.186315473810476 0.995942502972251 0.999814563001473 GO:0001653 peptide receptor activity 1/820 128/18639 0.0078125 0.17758193597561 0.996908166832153 0.999814563001473 GO:0031490 chromatin DNA binding 1/820 128/18639 0.0078125 0.17758193597561 0.996908166832153 0.999814563001473 GO:0003730 mRNA 3'-UTR binding 4/820 262/18639 0.0152671755725191 0.347030348166077 0.99728996234832 0.999814563001473 GO:0140101 catalytic activity, acting on a tRNA 1/820 139/18639 0.00719424460431655 0.163528689243727 0.998121964763178 0.999814563001473 GO:0140767 enzyme-substrate adaptor activity 1/820 139/18639 0.00719424460431655 0.163528689243727 0.998121964763178 0.999814563001473 GO:0008194 UDP-glycosyltransferase activity 1/820 145/18639 0.00689655172413793 0.156761984861228 0.998569293352644 0.999814563001473 GO:0016758 hexosyltransferase activity 2/820 197/18639 0.0101522842639594 0.230766373653584 0.998628867269339 0.999814563001473 GO:0015293 symporter activity 1/820 146/18639 0.00684931506849315 0.155688272636151 0.998632729031828 0.999814563001473 GO:0045182 translation regulator activity 5/820 356/18639 0.0140449438202247 0.319248424225815 0.999612639514556 0.999814563001473 GO:0140097 catalytic activity, acting on DNA 4/820 336/18639 0.0119047619047619 0.270601045296167 0.999814563001473 0.999814563001473