ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 82/479 175/18639 0.468571428571429 18.2332001192962 8.67297642034948e-84 5.8889509894173e-81 GO:0015078 proton transmembrane transporter activity 39/479 185/18639 0.210810810810811 8.20313716639395 1.16208394338674e-24 3.94527498779797e-22 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 22/479 68/18639 0.323529411764706 12.5892791354538 8.69408709398046e-19 1.96776171227091e-16 GO:0022853 active monoatomic ion transmembrane transporter activity 27/479 118/18639 0.228813559322034 8.90366582923463 2.07449869050391e-18 3.52146152713039e-16 GO:0009055 electron transfer activity 26/479 116/18639 0.224137931034483 8.72172629760277 1.55113890152749e-17 2.10644662827433e-15 GO:0015399 primary active transmembrane transporter activity 27/479 166/18639 0.162650602409639 6.32911185451619 1.79329943921134e-14 2.0294171987075e-12 GO:0019843 rRNA binding 16/479 65/18639 0.246153846153846 9.5784165729886 5.74899989268714e-12 5.57652989590653e-10 GO:0003954 NADH dehydrogenase activity 13/479 44/18639 0.295454545454545 11.4968210286582 4.55554211889952e-11 3.86651637341597e-09 GO:0008137 NADH dehydrogenase (ubiquinone) activity 12/479 41/18639 0.292682926829268 11.3889709251999 2.90551881457221e-10 2.19205252788281e-08 GO:0031386 protein tag activity 8/479 15/18639 0.533333333333333 20.753235908142 9.86144423372943e-10 5.57993386225191e-08 GO:0055105 ubiquitin-protein transferase inhibitor activity 8/479 15/18639 0.533333333333333 20.753235908142 9.86144423372943e-10 5.57993386225191e-08 GO:0141047 molecular tag activity 8/479 15/18639 0.533333333333333 20.753235908142 9.86144423372943e-10 5.57993386225191e-08 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 13/479 58/18639 0.224137931034483 8.72172629760277 1.99449109672966e-09 1.037737144615e-07 GO:1990948 ubiquitin ligase inhibitor activity 7/479 11/18639 0.636363636363636 24.762383754033 2.13966421570102e-09 1.037737144615e-07 GO:0016209 antioxidant activity 15/479 86/18639 0.174418604651163 6.78703209205224 4.63050295623672e-09 2.09607433818982e-07 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 8/479 18/18639 0.444444444444444 17.294363256785 6.26463793101163e-09 2.65855572197306e-07 GO:0004129 cytochrome-c oxidase activity 7/479 15/18639 0.466666666666667 18.1590814196242 3.81512586160587e-08 1.52380615295905e-06 GO:0016651 oxidoreductase activity, acting on NAD(P)H 14/479 88/18639 0.159090909090909 6.19059593850826 5.12868316994125e-08 1.93465326243895e-06 GO:0016675 oxidoreductase activity, acting on a heme group of donors 7/479 16/18639 0.4375 17.0241388308977 6.63248701434749e-08 2.37024141196945e-06 GO:0048027 mRNA 5'-UTR binding 8/479 24/18639 0.333333333333333 12.9707724425887 9.19104074000099e-08 3.12035833123034e-06 GO:0004601 peroxidase activity 11/479 57/18639 0.192982456140351 7.50939457202505 1.82792053357515e-07 5.91027639189298e-06 GO:0015252 proton channel activity 8/479 27/18639 0.296296296296296 11.5295755045233 2.59227758097974e-07 7.81493072746673e-06 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 11/479 59/18639 0.186440677966102 7.25483882382081 2.64717830238196e-07 7.81493072746673e-06 GO:0022804 active transmembrane transporter activity 32/479 457/18639 0.0700218818380744 2.7247136859705 3.23529449945972e-07 9.15318735472146e-06 GO:0045296 cadherin binding 26/479 334/18639 0.0778443113772455 3.02910254647282 5.82562669125e-07 1.5822402093435e-05 GO:0055106 ubiquitin-protein transferase regulator activity 8/479 36/18639 0.222222222222222 8.64718162839248 2.88319041751496e-06 7.52956266727945e-05 GO:0031625 ubiquitin protein ligase binding 23/479 302/18639 0.076158940397351 2.96352085608815 3.77406058538967e-06 9.49106347214661e-05 GO:0048407 platelet-derived growth factor binding 5/479 11/18639 0.454545454545455 17.6874169671664 4.46267503968416e-06 0.000108219869712341 GO:0044389 ubiquitin-like protein ligase binding 23/479 322/18639 0.0714285714285714 2.77945123769758 1.08420459968461e-05 0.000253853421788224 GO:0005178 integrin binding 15/479 161/18639 0.093167701863354 3.62537117960554 1.80483770357669e-05 0.000408494933576191 GO:0098631 cell adhesion mediator activity 10/479 76/18639 0.131578947368421 5.12004175365345 2.39206299167356e-05 0.000523938958498821 GO:0019838 growth factor binding 13/479 136/18639 0.0955882352941176 3.71955974456588 4.9567546800031e-05 0.00105176138366316 GO:0003746 translation elongation factor activity 5/479 18/18639 0.277777777777778 10.8089770354906 7.12925026835325e-05 0.00146689725218541 GO:0016835 carbon-oxygen lyase activity 9/479 79/18639 0.113924050632911 4.43304880949235 0.00018946189910974 0.00378366557339746 GO:0050840 extracellular matrix binding 8/479 67/18639 0.119402985074627 4.64624684510641 0.000309704388653156 0.00556377393033667 GO:0042625 ATPase-coupled ion transmembrane transporter activity 5/479 24/18639 0.208333333333333 8.10673277661795 0.000311374682404703 0.00556377393033667 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 5/479 24/18639 0.208333333333333 8.10673277661795 0.000311374682404703 0.00556377393033667 GO:0046961 proton-transporting ATPase activity, rotational mechanism 5/479 24/18639 0.208333333333333 8.10673277661795 0.000311374682404703 0.00556377393033667 GO:0016860 intramolecular oxidoreductase activity 7/479 53/18639 0.132075471698113 5.13936266593138 0.000392900926221845 0.00684050586934956 GO:0005518 collagen binding 8/479 72/18639 0.111111111111111 4.32359081419624 0.000508261902595364 0.0086277457965563 GO:0004364 glutathione transferase activity 5/479 27/18639 0.185185185185185 7.20598469032707 0.000555024277281543 0.00919174351888213 GO:0043236 laminin binding 5/479 29/18639 0.172413793103448 6.7090202289252 0.000782662255846481 0.0123665825721089 GO:0002020 protease binding 11/479 136/18639 0.0808823529411765 3.14731978386344 0.000783156186451668 0.0123665825721089 GO:0030020 extracellular matrix structural constituent conferring tensile strength 6/479 44/18639 0.136363636363636 5.30622509014993 0.000860733384192596 0.0132826810878812 GO:0016505 peptidase activator activity involved in apoptotic process 4/479 20/18639 0.2 7.78246346555324 0.00150447212655196 0.022700812753973 GO:0005522 profilin binding 3/479 10/18639 0.3 11.6736951983299 0.00176884299926851 0.0261096607935505 GO:0042277 peptide binding 15/479 249/18639 0.0602409638554217 2.34411550167266 0.00205129325042688 0.0296346407880819 GO:0043021 ribonucleoprotein complex binding 12/479 177/18639 0.0677966101694915 2.63812320866211 0.00213171700773453 0.0301549135052447 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 3/479 11/18639 0.272727272727273 10.6124501802999 0.00238598401815903 0.0324016629665996 GO:0019864 IgG binding 3/479 11/18639 0.272727272727273 10.6124501802999 0.00238598401815903 0.0324016629665996 GO:0016853 isomerase activity 12/479 180/18639 0.0666666666666667 2.59415448851774 0.0024509559594091 0.032631354832133 GO:0004602 glutathione peroxidase activity 4/479 23/18639 0.173913043478261 6.76735953526368 0.00258720418907425 0.0331455027241777 GO:0017134 fibroblast growth factor binding 4/479 23/18639 0.173913043478261 6.76735953526368 0.00258720418907425 0.0331455027241777 GO:0098632 cell-cell adhesion mediator activity 6/479 55/18639 0.109090909090909 4.24498007211995 0.00278856273149369 0.035063594346004 GO:0097371 MDM2/MDM4 family protein binding 3/479 12/18639 0.25 9.72807933194155 0.00312099333223764 0.0385300813198065 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 5/479 40/18639 0.125 4.86403966597077 0.00344064865922217 0.0417178649930689 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 3/479 13/18639 0.230769230769231 8.97976553717681 0.00398046532836203 0.046598895826859 GO:0008035 high-density lipoprotein particle binding 3/479 13/18639 0.230769230769231 8.97976553717681 0.00398046532836203 0.046598895826859 GO:0050750 low-density lipoprotein particle receptor binding 4/479 26/18639 0.153846153846154 5.98651035811787 0.00411062711878457 0.0473070476890631 GO:0005201 extracellular matrix structural constituent 11/479 168/18639 0.0654761904761905 2.54783030122279 0.00418852362012699 0.0474001256344371 GO:0048306 calcium-dependent protein binding 7/479 80/18639 0.0875 3.40482776617954 0.00447853448398296 0.0498512281085972 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 6/479 61/18639 0.0983606557377049 3.82744104863274 0.00469580761611779 0.0514266672797416 GO:0033218 amide binding 14/479 247/18639 0.0566801619433198 2.20555644772764 0.00489786579995317 0.052788109177273 GO:0005507 copper ion binding 6/479 63/18639 0.0952380952380952 3.70593498359678 0.00550530638726178 0.0584078599523554 GO:0003785 actin monomer binding 4/479 29/18639 0.137931034482759 5.36721618314016 0.00614677822809628 0.0642101910288826 GO:0038024 cargo receptor activity 6/479 65/18639 0.0923076923076923 3.59190621487072 0.00641235573395317 0.0659695385356697 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 11/479 181/18639 0.0607734806629834 2.36483696467087 0.00725972875574991 0.073498186522218 GO:0034450 ubiquitin-ubiquitin ligase activity 3/479 16/18639 0.1875 7.29605949895616 0.00736064312740917 0.073498186522218 GO:0070325 lipoprotein particle receptor binding 4/479 31/18639 0.129032258064516 5.02094417132467 0.00782169436330778 0.0769700068505215 GO:0005200 structural constituent of cytoskeleton 8/479 112/18639 0.0714285714285714 2.77945123769758 0.00831942181382226 0.0806983915940759 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 3/479 17/18639 0.176470588235294 6.86687952842933 0.00876958635821884 0.0827020713504249 GO:0016018 cyclosporin A binding 3/479 17/18639 0.176470588235294 6.86687952842933 0.00876958635821884 0.0827020713504249 GO:0035615 clathrin adaptor activity 3/479 18/18639 0.166666666666667 6.48538622129436 0.0103255725599395 0.0934808502426524 GO:0070064 proline-rich region binding 3/479 18/18639 0.166666666666667 6.48538622129436 0.0103255725599395 0.0934808502426524 GO:0098641 cadherin binding involved in cell-cell adhesion 3/479 18/18639 0.166666666666667 6.48538622129436 0.0103255725599395 0.0934808502426524 GO:0004857 enzyme inhibitor activity 19/479 416/18639 0.0456730769230769 1.77724526256624 0.0116248144956798 0.10385854003377 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 5/479 54/18639 0.0925925925925926 3.60299234516354 0.0123489469035255 0.108895259058361 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 4/479 36/18639 0.111111111111111 4.32359081419624 0.01324469176998 0.112414321397705 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 4/479 36/18639 0.111111111111111 4.32359081419624 0.01324469176998 0.112414321397705 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 4/479 36/18639 0.111111111111111 4.32359081419624 0.01324469176998 0.112414321397705 GO:0016504 peptidase activator activity 5/479 57/18639 0.087719298245614 3.4133611691023 0.0153641223291779 0.128793074833479 GO:0140312 cargo adaptor activity 3/479 21/18639 0.142857142857143 5.55890247539517 0.0159003044817204 0.131033979737036 GO:0046332 SMAD binding 6/479 79/18639 0.0759493670886076 2.9553658729949 0.0160174084214639 0.131033979737036 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 4/479 39/18639 0.102564102564103 3.99100690541192 0.0174174202929239 0.140790814034468 GO:0005506 iron ion binding 9/479 154/18639 0.0584415584415584 2.27409646720711 0.0181988460306783 0.145376664174478 GO:0001540 amyloid-beta binding 6/479 83/18639 0.072289156626506 2.81293860200719 0.0199838595696887 0.156851805274714 GO:0016836 hydro-lyase activity 5/479 61/18639 0.0819672131147541 3.18953420719395 0.0200973594387337 0.156851805274714 GO:0031681 G-protein beta-subunit binding 3/479 23/18639 0.130434782608696 5.07551965144776 0.0203883983471249 0.157315028155657 GO:0016859 cis-trans isomerase activity 4/479 42/18639 0.0952380952380952 3.70593498359678 0.0223264992726959 0.166590033034731 GO:0031492 nucleosomal DNA binding 4/479 42/18639 0.0952380952380952 3.70593498359678 0.0223264992726959 0.166590033034731 GO:0048487 beta-tubulin binding 4/479 42/18639 0.0952380952380952 3.70593498359678 0.0223264992726959 0.166590033034731 GO:0008200 ion channel inhibitor activity 4/479 43/18639 0.0930232558139535 3.61975044909453 0.0241315903178952 0.176692757653985 GO:0044325 transmembrane transporter binding 8/479 136/18639 0.0588235294117647 2.28895984280978 0.0243475500076234 0.176692757653985 GO:0003924 GTPase activity 15/479 331/18639 0.0453172205438066 1.76339806621297 0.0247492715405146 0.176692757653985 GO:0001848 complement binding 3/479 25/18639 0.12 4.66947807933194 0.0255005546200437 0.176692757653985 GO:0120020 cholesterol transfer activity 3/479 25/18639 0.12 4.66947807933194 0.0255005546200437 0.176692757653985 GO:0043022 ribosome binding 7/479 112/18639 0.0625 2.43201983298539 0.0255537468143109 0.176692757653985 GO:0003680 minor groove of adenine-thymine-rich DNA binding 2/479 10/18639 0.2 7.78246346555324 0.0258709814498166 0.176692757653985 GO:0008239 dipeptidyl-peptidase activity 2/479 10/18639 0.2 7.78246346555324 0.0258709814498166 0.176692757653985 GO:0016248 channel inhibitor activity 4/479 44/18639 0.0909090909090909 3.53748339343329 0.0260224974453587 0.176692757653985 GO:0141110 transporter inhibitor activity 4/479 45/18639 0.0888888888888889 3.45887265135699 0.0279999270383965 0.184704616982143 GO:0005160 transforming growth factor beta receptor binding 3/479 26/18639 0.115384615384615 4.48988276858841 0.0282905451636862 0.184704616982143 GO:0019865 immunoglobulin binding 3/479 26/18639 0.115384615384615 4.48988276858841 0.0282905451636862 0.184704616982143 GO:0050681 nuclear androgen receptor binding 3/479 26/18639 0.115384615384615 4.48988276858841 0.0282905451636862 0.184704616982143 GO:0008199 ferric iron binding 2/479 11/18639 0.181818181818182 7.07496678686658 0.0310898697679627 0.191072674958872 GO:0015217 ADP transmembrane transporter activity 2/479 11/18639 0.181818181818182 7.07496678686658 0.0310898697679627 0.191072674958872 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/479 11/18639 0.181818181818182 7.07496678686658 0.0310898697679627 0.191072674958872 GO:0034713 type I transforming growth factor beta receptor binding 2/479 11/18639 0.181818181818182 7.07496678686658 0.0310898697679627 0.191072674958872 GO:0050786 RAGE receptor binding 2/479 11/18639 0.181818181818182 7.07496678686658 0.0310898697679627 0.191072674958872 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/479 11/18639 0.181818181818182 7.07496678686658 0.0310898697679627 0.191072674958872 GO:0023026 MHC class II protein complex binding 3/479 27/18639 0.111111111111111 4.32359081419624 0.0312357392053532 0.191072674958872 GO:0005504 fatty acid binding 4/479 47/18639 0.0851063829787234 3.31168658108648 0.0322166444397975 0.194340933339855 GO:0061134 peptidase regulator activity 11/479 226/18639 0.0486725663716814 1.89396234781163 0.0323424528238639 0.194340933339855 GO:0097110 scaffold protein binding 5/479 70/18639 0.0714285714285714 2.77945123769758 0.0339776113527333 0.201109035727254 GO:0097718 disordered domain specific binding 3/479 28/18639 0.107142857142857 4.16917685654638 0.0343351998904405 0.201109035727254 GO:0016829 lyase activity 10/479 200/18639 0.05 1.94561586638831 0.0343573610373513 0.201109035727254 GO:0005049 nuclear export signal receptor activity 2/479 12/18639 0.166666666666667 6.48538622129436 0.0366836450551077 0.209312562961497 GO:0005165 neurotrophin receptor binding 2/479 12/18639 0.166666666666667 6.48538622129436 0.0366836450551077 0.209312562961497 GO:0008179 adenylate cyclase binding 2/479 12/18639 0.166666666666667 6.48538622129436 0.0366836450551077 0.209312562961497 GO:0016769 transferase activity, transferring nitrogenous groups 3/479 30/18639 0.1 3.89123173277662 0.0409917930617898 0.231945229074628 GO:0031491 nucleosome binding 5/479 74/18639 0.0675675675675676 2.62921063025447 0.0416698904277282 0.233833517358905 GO:0019855 calcium channel inhibitor activity 2/479 13/18639 0.153846153846154 5.98651035811787 0.0426296777326979 0.235329684394324 GO:0035325 Toll-like receptor binding 2/479 13/18639 0.153846153846154 5.98651035811787 0.0426296777326979 0.235329684394324 GO:0071813 lipoprotein particle binding 3/479 32/18639 0.09375 3.64802974947808 0.0482475897009452 0.253491171142074 GO:0071814 protein-lipid complex binding 3/479 32/18639 0.09375 3.64802974947808 0.0482475897009452 0.253491171142074 GO:0120015 sterol transfer activity 3/479 32/18639 0.09375 3.64802974947808 0.0482475897009452 0.253491171142074 GO:0005347 ATP transmembrane transporter activity 2/479 14/18639 0.142857142857143 5.55890247539517 0.0489062495134192 0.253491171142074 GO:0016530 metallochaperone activity 2/479 14/18639 0.142857142857143 5.55890247539517 0.0489062495134192 0.253491171142074 GO:0019763 immunoglobulin receptor activity 2/479 14/18639 0.142857142857143 5.55890247539517 0.0489062495134192 0.253491171142074 GO:0032036 myosin heavy chain binding 2/479 14/18639 0.142857142857143 5.55890247539517 0.0489062495134192 0.253491171142074 GO:0044548 S100 protein binding 2/479 14/18639 0.142857142857143 5.55890247539517 0.0489062495134192 0.253491171142074 GO:1901681 sulfur compound binding 12/479 275/18639 0.0436363636363636 1.69799202884798 0.0527083838862549 0.271128732263387 GO:0015035 protein-disulfide reductase activity 3/479 34/18639 0.0882352941176471 3.43343976421466 0.0560863081499595 0.286335362660319 GO:0001618 virus receptor activity 5/479 81/18639 0.0617283950617284 2.40199489677569 0.0574723050665881 0.29122160552398 GO:0140272 exogenous protein binding 5/479 82/18639 0.0609756097560976 2.3727022760833 0.0599746884229761 0.301650469920005 GO:0008135 translation factor activity, RNA binding 5/479 83/18639 0.0602409638554217 2.34411550167266 0.0625382030930586 0.312231175736667 GO:0180051 translation factor activity 5/479 84/18639 0.0595238095238095 2.31620936474799 0.0651627171865231 0.322959744304009 GO:0016874 ligase activity 8/479 167/18639 0.0479041916167665 1.86406310552173 0.0669822720136305 0.32957219345837 GO:0023023 MHC protein complex binding 3/479 37/18639 0.0810810810810811 3.15505275630537 0.0688945091953642 0.330074847111921 GO:0004550 nucleoside diphosphate kinase activity 2/479 17/18639 0.117647058823529 4.57791968561955 0.0695150267113471 0.330074847111921 GO:0008429 phosphatidylethanolamine binding 2/479 17/18639 0.117647058823529 4.57791968561955 0.0695150267113471 0.330074847111921 GO:0030169 low-density lipoprotein particle binding 2/479 17/18639 0.117647058823529 4.57791968561955 0.0695150267113471 0.330074847111921 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 2/479 17/18639 0.117647058823529 4.57791968561955 0.0695150267113471 0.330074847111921 GO:1990381 ubiquitin-specific protease binding 2/479 18/18639 0.111111111111111 4.32359081419624 0.076913708480273 0.362669500403509 GO:0016776 phosphotransferase activity, phosphate group as acceptor 3/479 39/18639 0.0769230769230769 2.99325517905894 0.0781008825680993 0.365727581129237 GO:0015036 disulfide oxidoreductase activity 3/479 40/18639 0.075 2.91842379958246 0.0828952464315486 0.380181236398525 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 3/479 40/18639 0.075 2.91842379958246 0.0828952464315486 0.380181236398525 GO:0071949 FAD binding 3/479 40/18639 0.075 2.91842379958246 0.0828952464315486 0.380181236398525 GO:0005346 purine ribonucleotide transmembrane transporter activity 2/479 19/18639 0.105263157894737 4.09603340292276 0.0845469318058576 0.380181236398525 GO:0008301 DNA binding, bending 2/479 19/18639 0.105263157894737 4.09603340292276 0.0845469318058576 0.380181236398525 GO:0050145 nucleoside monophosphate kinase activity 2/479 19/18639 0.105263157894737 4.09603340292276 0.0845469318058576 0.380181236398525 GO:0120013 lipid transfer activity 4/479 65/18639 0.0615384615384615 2.39460414324715 0.0859249990173803 0.383836015347377 GO:0019209 kinase activator activity 7/479 148/18639 0.0472972972972973 1.84044744117813 0.0877045857404392 0.384676657028815 GO:0042287 MHC protein binding 3/479 41/18639 0.0731707317073171 2.84724273129996 0.087812786214236 0.384676657028815 GO:0140318 protein transporter activity 3/479 41/18639 0.0731707317073171 2.84724273129996 0.087812786214236 0.384676657028815 GO:0051082 unfolded protein binding 6/479 121/18639 0.0495867768595041 1.92953639641816 0.0920247889224323 0.396511201135156 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 2/479 20/18639 0.1 3.89123173277662 0.092397814504048 0.396511201135156 GO:0042288 MHC class I protein binding 2/479 20/18639 0.1 3.89123173277662 0.092397814504048 0.396511201135156 GO:0008307 structural constituent of muscle 3/479 42/18639 0.0714285714285714 2.77945123769758 0.0928501929020467 0.396511201135156 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/479 21/18639 0.0952380952380952 3.70593498359678 0.100450183980082 0.426285468265475 GO:0019205 nucleobase-containing compound kinase activity 3/479 44/18639 0.0681818181818182 2.65311254507497 0.103271033753212 0.432845876039696 GO:0030547 signaling receptor inhibitor activity 3/479 44/18639 0.0681818181818182 2.65311254507497 0.103271033753212 0.432845876039696 GO:0042626 ATPase-coupled transmembrane transporter activity 5/479 98/18639 0.0510204081632653 1.98532231264113 0.108148597950558 0.44191333431136 GO:0042605 peptide antigen binding 3/479 45/18639 0.0666666666666667 2.59415448851774 0.108647541375699 0.44191333431136 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/479 22/18639 0.0909090909090909 3.53748339343329 0.108688552032396 0.44191333431136 GO:0034062 5'-3' RNA polymerase activity 2/479 22/18639 0.0909090909090909 3.53748339343329 0.108688552032396 0.44191333431136 GO:0097747 RNA polymerase activity 2/479 22/18639 0.0909090909090909 3.53748339343329 0.108688552032396 0.44191333431136 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 3/479 46/18639 0.0652173913043478 2.53775982572388 0.114130080666555 0.461275742693992 GO:0000295 adenine nucleotide transmembrane transporter activity 2/479 23/18639 0.0869565217391304 3.38367976763184 0.117098090478613 0.467703549617518 GO:0099186 structural constituent of postsynapse 2/479 23/18639 0.0869565217391304 3.38367976763184 0.117098090478613 0.467703549617518 GO:0048029 monosaccharide binding 4/479 74/18639 0.0540540540540541 2.10336850420358 0.12273756920147 0.48736145899297 GO:0003713 transcription coactivator activity 10/479 256/18639 0.0390625 1.52001239561587 0.125198447243207 0.493215425118832 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 2/479 24/18639 0.0833333333333333 3.24269311064718 0.125664607578141 0.493215425118832 GO:0017022 myosin binding 4/479 76/18639 0.0526315789473684 2.04801670146138 0.13170505974803 0.513952503269612 GO:0051540 metal cluster binding 4/479 77/18639 0.051948051948052 2.02141908196188 0.136287511242945 0.528795543622626 GO:0003712 transcription coregulator activity 17/479 495/18639 0.0343434343434343 1.33638261529702 0.139234116114808 0.537158891147468 GO:0016247 channel regulator activity 7/479 168/18639 0.0416666666666667 1.62134655532359 0.142716465934273 0.537253523945528 GO:0008198 ferrous iron binding 2/479 26/18639 0.0769230769230769 2.99325517905894 0.143214856898587 0.537253523945528 GO:0015216 purine nucleotide transmembrane transporter activity 2/479 26/18639 0.0769230769230769 2.99325517905894 0.143214856898587 0.537253523945528 GO:0097602 cullin family protein binding 2/479 26/18639 0.0769230769230769 2.99325517905894 0.143214856898587 0.537253523945528 GO:0120014 phospholipid transfer activity 2/479 26/18639 0.0769230769230769 2.99325517905894 0.143214856898587 0.537253523945528 GO:0033293 monocarboxylic acid binding 4/479 79/18639 0.0506329113924051 1.97024391532993 0.145642117079359 0.543357129103763 GO:0030295 protein kinase activator activity 6/479 139/18639 0.0431654676258993 1.67966837386041 0.148772158918657 0.547057356385914 GO:0141108 transporter regulator activity 7/479 170/18639 0.0411764705882353 1.60227188996684 0.148969893923726 0.547057356385914 GO:0005080 protein kinase C binding 3/479 52/18639 0.0576923076923077 2.2449413842942 0.149050973389387 0.547057356385914 GO:0005044 scavenger receptor activity 2/479 27/18639 0.0740740740740741 2.88239387613083 0.152173186314046 0.552543280787363 GO:0008320 protein transmembrane transporter activity 2/479 27/18639 0.0740740740740741 2.88239387613083 0.152173186314046 0.552543280787363 GO:0005246 calcium channel regulator activity 3/479 53/18639 0.0566037735849057 2.20258399968488 0.155174969366408 0.560445767020165 GO:0045499 chemorepellent activity 2/479 28/18639 0.0714285714285714 2.77945123769758 0.161237646808169 0.567742971477378 GO:0003925 G protein activity 3/479 54/18639 0.0555555555555556 2.16179540709812 0.161376131804321 0.567742971477378 GO:0015485 cholesterol binding 3/479 54/18639 0.0555555555555556 2.16179540709812 0.161376131804321 0.567742971477378 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 3/479 54/18639 0.0555555555555556 2.16179540709812 0.161376131804321 0.567742971477378 GO:0051287 NAD binding 3/479 54/18639 0.0555555555555556 2.16179540709812 0.161376131804321 0.567742971477378 GO:0140313 molecular sequestering activity 3/479 55/18639 0.0545454545454545 2.12249003605997 0.167650867355904 0.586778035745665 GO:0005539 glycosaminoglycan binding 9/479 242/18639 0.0371900826446281 1.44715229731362 0.172300914499721 0.599960620232361 GO:0015215 nucleotide transmembrane transporter activity 2/479 30/18639 0.0666666666666667 2.59415448851774 0.179640123403221 0.612942933622047 GO:0033612 receptor serine/threonine kinase binding 2/479 30/18639 0.0666666666666667 2.59415448851774 0.179640123403221 0.612942933622047 GO:0048019 receptor antagonist activity 2/479 30/18639 0.0666666666666667 2.59415448851774 0.179640123403221 0.612942933622047 GO:0098918 structural constituent of synapse 2/479 30/18639 0.0666666666666667 2.59415448851774 0.179640123403221 0.612942933622047 GO:0072349 modified amino acid transmembrane transporter activity 2/479 31/18639 0.0645161290322581 2.51047208566233 0.188956977968405 0.641508940202736 GO:0022884 macromolecule transmembrane transporter activity 2/479 32/18639 0.0625 2.43201983298539 0.198337603852903 0.663245260307312 GO:0043425 bHLH transcription factor binding 2/479 32/18639 0.0625 2.43201983298539 0.198337603852903 0.663245260307312 GO:0140142 nucleocytoplasmic carrier activity 2/479 32/18639 0.0625 2.43201983298539 0.198337603852903 0.663245260307312 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 3/479 60/18639 0.05 1.94561586638831 0.200004028721063 0.663245260307312 GO:0031406 carboxylic acid binding 7/479 187/18639 0.0374331550802139 1.45661080906077 0.206922794793614 0.663245260307312 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2/479 33/18639 0.0606060606060606 2.35832226228886 0.207772596082934 0.663245260307312 GO:0030296 protein tyrosine kinase activator activity 2/479 33/18639 0.0606060606060606 2.35832226228886 0.207772596082934 0.663245260307312 GO:0043177 organic acid binding 7/479 189/18639 0.037037037037037 1.44119693806541 0.214247734854067 0.663245260307312 GO:0051213 dioxygenase activity 4/479 93/18639 0.043010752688172 1.67364805710822 0.217171945743194 0.663245260307312 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 2/479 34/18639 0.0588235294117647 2.28895984280978 0.217252989078745 0.663245260307312 GO:0042562 hormone binding 4/479 94/18639 0.0425531914893617 1.65584329054324 0.22261484064252 0.663245260307312 GO:0001094 TFIID-class transcription factor complex binding 1/479 10/18639 0.1 3.89123173277662 0.229265689564345 0.663245260307312 GO:0005031 tumor necrosis factor receptor activity 1/479 10/18639 0.1 3.89123173277662 0.229265689564345 0.663245260307312 GO:0005345 purine nucleobase transmembrane transporter activity 1/479 10/18639 0.1 3.89123173277662 0.229265689564345 0.663245260307312 GO:0005528 FK506 binding 1/479 10/18639 0.1 3.89123173277662 0.229265689564345 0.663245260307312 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/479 10/18639 0.1 3.89123173277662 0.229265689564345 0.663245260307312 GO:0016868 intramolecular phosphotransferase activity 1/479 10/18639 0.1 3.89123173277662 0.229265689564345 0.663245260307312 GO:0030957 Tat protein binding 1/479 10/18639 0.1 3.89123173277662 0.229265689564345 0.663245260307312 GO:0031419 cobalamin binding 1/479 10/18639 0.1 3.89123173277662 0.229265689564345 0.663245260307312 GO:0031996 thioesterase binding 1/479 10/18639 0.1 3.89123173277662 0.229265689564345 0.663245260307312 GO:0032356 oxidized DNA binding 1/479 10/18639 0.1 3.89123173277662 0.229265689564345 0.663245260307312 GO:0042975 peroxisome proliferator activated receptor binding 1/479 10/18639 0.1 3.89123173277662 0.229265689564345 0.663245260307312 GO:0043295 glutathione binding 1/479 10/18639 0.1 3.89123173277662 0.229265689564345 0.663245260307312 GO:0051880 G-quadruplex DNA binding 1/479 10/18639 0.1 3.89123173277662 0.229265689564345 0.663245260307312 GO:0070097 delta-catenin binding 1/479 10/18639 0.1 3.89123173277662 0.229265689564345 0.663245260307312 GO:0070513 death domain binding 1/479 10/18639 0.1 3.89123173277662 0.229265689564345 0.663245260307312 GO:0097177 mitochondrial ribosome binding 1/479 10/18639 0.1 3.89123173277662 0.229265689564345 0.663245260307312 GO:1905394 retromer complex binding 1/479 10/18639 0.1 3.89123173277662 0.229265689564345 0.663245260307312 GO:0099106 ion channel regulator activity 6/479 160/18639 0.0375 1.45921189979123 0.230064131626785 0.663245260307312 GO:0019001 guanyl nucleotide binding 13/479 400/18639 0.0325 1.2646503131524 0.23148142152275 0.663245260307312 GO:0032561 guanyl ribonucleotide binding 13/479 400/18639 0.0325 1.2646503131524 0.23148142152275 0.663245260307312 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 5/479 128/18639 0.0390625 1.52001239561587 0.233317319546363 0.663245260307312 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/479 36/18639 0.0555555555555556 2.16179540709812 0.236316214803995 0.663245260307312 GO:0045505 dynein intermediate chain binding 2/479 36/18639 0.0555555555555556 2.16179540709812 0.236316214803995 0.663245260307312 GO:0008083 growth factor activity 6/479 162/18639 0.037037037037037 1.44119693806541 0.238464168605591 0.663245260307312 GO:0043394 proteoglycan binding 2/479 37/18639 0.0540540540540541 2.10336850420358 0.245883169410203 0.663245260307312 GO:0000099 sulfur amino acid transmembrane transporter activity 1/479 11/18639 0.0909090909090909 3.53748339343329 0.249083271543983 0.663245260307312 GO:0005114 type II transforming growth factor beta receptor binding 1/479 11/18639 0.0909090909090909 3.53748339343329 0.249083271543983 0.663245260307312 GO:0005536 D-glucose binding 1/479 11/18639 0.0909090909090909 3.53748339343329 0.249083271543983 0.663245260307312 GO:0008432 JUN kinase binding 1/479 11/18639 0.0909090909090909 3.53748339343329 0.249083271543983 0.663245260307312 GO:0008503 benzodiazepine receptor activity 1/479 11/18639 0.0909090909090909 3.53748339343329 0.249083271543983 0.663245260307312 GO:0008526 phosphatidylinositol transfer activity 1/479 11/18639 0.0909090909090909 3.53748339343329 0.249083271543983 0.663245260307312 GO:0010854 adenylate cyclase regulator activity 1/479 11/18639 0.0909090909090909 3.53748339343329 0.249083271543983 0.663245260307312 GO:0015205 nucleobase transmembrane transporter activity 1/479 11/18639 0.0909090909090909 3.53748339343329 0.249083271543983 0.663245260307312 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/479 11/18639 0.0909090909090909 3.53748339343329 0.249083271543983 0.663245260307312 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/479 11/18639 0.0909090909090909 3.53748339343329 0.249083271543983 0.663245260307312 GO:0032050 clathrin heavy chain binding 1/479 11/18639 0.0909090909090909 3.53748339343329 0.249083271543983 0.663245260307312 GO:0032794 GTPase activating protein binding 1/479 11/18639 0.0909090909090909 3.53748339343329 0.249083271543983 0.663245260307312 GO:0035252 UDP-xylosyltransferase activity 1/479 11/18639 0.0909090909090909 3.53748339343329 0.249083271543983 0.663245260307312 GO:0042285 xylosyltransferase activity 1/479 11/18639 0.0909090909090909 3.53748339343329 0.249083271543983 0.663245260307312 GO:0045294 alpha-catenin binding 1/479 11/18639 0.0909090909090909 3.53748339343329 0.249083271543983 0.663245260307312 GO:0050998 nitric-oxide synthase binding 1/479 11/18639 0.0909090909090909 3.53748339343329 0.249083271543983 0.663245260307312 GO:0070697 activin receptor binding 1/479 11/18639 0.0909090909090909 3.53748339343329 0.249083271543983 0.663245260307312 GO:0070990 snRNP binding 1/479 11/18639 0.0909090909090909 3.53748339343329 0.249083271543983 0.663245260307312 GO:1900750 oligopeptide binding 1/479 11/18639 0.0909090909090909 3.53748339343329 0.249083271543983 0.663245260307312 GO:0032934 sterol binding 3/479 68/18639 0.0441176470588235 1.71671988210733 0.254335801793119 0.66548800365591 GO:0005125 cytokine activity 8/479 234/18639 0.0341880341880342 1.33033563513731 0.255197935450476 0.66548800365591 GO:0005109 frizzled binding 2/479 38/18639 0.0526315789473684 2.04801670146138 0.255463738603461 0.66548800365591 GO:0043531 ADP binding 2/479 38/18639 0.0526315789473684 2.04801670146138 0.255463738603461 0.66548800365591 GO:0051087 protein-folding chaperone binding 5/479 134/18639 0.0373134328358209 1.45195213909575 0.262182997114565 0.66548800365591 GO:0000217 DNA secondary structure binding 2/479 39/18639 0.0512820512820513 1.99550345270596 0.265050920010779 0.66548800365591 GO:0008238 exopeptidase activity 4/479 102/18639 0.0392156862745098 1.52597322853985 0.267292488715054 0.66548800365591 GO:0004032 aldose reductase (NADPH) activity 1/479 12/18639 0.0833333333333333 3.24269311064718 0.268392328497517 0.66548800365591 GO:0005078 MAP-kinase scaffold activity 1/479 12/18639 0.0833333333333333 3.24269311064718 0.268392328497517 0.66548800365591 GO:0005527 macrolide binding 1/479 12/18639 0.0833333333333333 3.24269311064718 0.268392328497517 0.66548800365591 GO:0010853 cyclase activator activity 1/479 12/18639 0.0833333333333333 3.24269311064718 0.268392328497517 0.66548800365591 GO:0016208 AMP binding 1/479 12/18639 0.0833333333333333 3.24269311064718 0.268392328497517 0.66548800365591 GO:0031543 peptidyl-proline dioxygenase activity 1/479 12/18639 0.0833333333333333 3.24269311064718 0.268392328497517 0.66548800365591 GO:0034452 dynactin binding 1/479 12/18639 0.0833333333333333 3.24269311064718 0.268392328497517 0.66548800365591 GO:0035497 cAMP response element binding 1/479 12/18639 0.0833333333333333 3.24269311064718 0.268392328497517 0.66548800365591 GO:0045295 gamma-catenin binding 1/479 12/18639 0.0833333333333333 3.24269311064718 0.268392328497517 0.66548800365591 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/479 12/18639 0.0833333333333333 3.24269311064718 0.268392328497517 0.66548800365591 GO:1990459 transferrin receptor binding 1/479 12/18639 0.0833333333333333 3.24269311064718 0.268392328497517 0.66548800365591 GO:0030414 peptidase inhibitor activity 6/479 169/18639 0.0355029585798817 1.38150239033489 0.268547441828747 0.66548800365591 GO:0003714 transcription corepressor activity 7/479 204/18639 0.0343137254901961 1.33522657497237 0.271884915591962 0.665572677038418 GO:0004177 aminopeptidase activity 2/479 40/18639 0.05 1.94561586638831 0.274638060725475 0.665572677038418 GO:0050997 quaternary ammonium group binding 2/479 40/18639 0.05 1.94561586638831 0.274638060725475 0.665572677038418 GO:0061791 GTPase motor activity 2/479 40/18639 0.05 1.94561586638831 0.274638060725475 0.665572677038418 GO:1990606 membrane scission GTPase motor activity 2/479 40/18639 0.05 1.94561586638831 0.274638060725475 0.665572677038418 GO:0005126 cytokine receptor binding 9/479 275/18639 0.0327272727272727 1.27349402163598 0.277139226751603 0.665572677038418 GO:0008201 heparin binding 6/479 172/18639 0.0348837209302326 1.35740641841045 0.281722487683851 0.665572677038418 GO:0001530 lipopolysaccharide binding 2/479 41/18639 0.0487804878048781 1.89816182086664 0.284218844033744 0.665572677038418 GO:0005035 death receptor activity 1/479 13/18639 0.0769230769230769 2.99325517905894 0.287205882727918 0.665572677038418 GO:0005542 folic acid binding 1/479 13/18639 0.0769230769230769 2.99325517905894 0.287205882727918 0.665572677038418 GO:0030955 potassium ion binding 1/479 13/18639 0.0769230769230769 2.99325517905894 0.287205882727918 0.665572677038418 GO:0031432 titin binding 1/479 13/18639 0.0769230769230769 2.99325517905894 0.287205882727918 0.665572677038418 GO:0031994 insulin-like growth factor I binding 1/479 13/18639 0.0769230769230769 2.99325517905894 0.287205882727918 0.665572677038418 GO:0035673 oligopeptide transmembrane transporter activity 1/479 13/18639 0.0769230769230769 2.99325517905894 0.287205882727918 0.665572677038418 GO:0039706 co-receptor binding 1/479 13/18639 0.0769230769230769 2.99325517905894 0.287205882727918 0.665572677038418 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/479 13/18639 0.0769230769230769 2.99325517905894 0.287205882727918 0.665572677038418 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/479 13/18639 0.0769230769230769 2.99325517905894 0.287205882727918 0.665572677038418 GO:0070700 BMP receptor binding 1/479 13/18639 0.0769230769230769 2.99325517905894 0.287205882727918 0.665572677038418 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/479 13/18639 0.0769230769230769 2.99325517905894 0.287205882727918 0.665572677038418 GO:0043539 protein serine/threonine kinase activator activity 3/479 73/18639 0.0410958904109589 1.59913632853834 0.289273375358293 0.667988697095117 GO:0004497 monooxygenase activity 4/479 106/18639 0.0377358490566038 1.46838933312325 0.290216002419822 0.667988697095117 GO:0035198 miRNA binding 2/479 42/18639 0.0476190476190476 1.85296749179839 0.293787276590328 0.671389538907637 GO:0051879 Hsp90 protein binding 2/479 42/18639 0.0476190476190476 1.85296749179839 0.293787276590328 0.671389538907637 GO:0004252 serine-type endopeptidase activity 6/479 176/18639 0.0340909090909091 1.32655627253748 0.299505586254465 0.671389538907637 GO:0048156 tau protein binding 2/479 43/18639 0.0465116279069767 1.80987522454726 0.303337676029083 0.671389538907637 GO:0019003 GDP binding 3/479 75/18639 0.04 1.55649269311065 0.303356857578292 0.671389538907637 GO:0044183 protein folding chaperone 3/479 75/18639 0.04 1.55649269311065 0.303356857578292 0.671389538907637 GO:0005313 L-glutamate transmembrane transporter activity 1/479 14/18639 0.0714285714285714 2.77945123769758 0.305536623744418 0.671389538907637 GO:0008191 metalloendopeptidase inhibitor activity 1/479 14/18639 0.0714285714285714 2.77945123769758 0.305536623744418 0.671389538907637 GO:0008494 translation activator activity 1/479 14/18639 0.0714285714285714 2.77945123769758 0.305536623744418 0.671389538907637 GO:0019992 diacylglycerol binding 1/479 14/18639 0.0714285714285714 2.77945123769758 0.305536623744418 0.671389538907637 GO:0031404 chloride ion binding 1/479 14/18639 0.0714285714285714 2.77945123769758 0.305536623744418 0.671389538907637 GO:0042043 neurexin family protein binding 1/479 14/18639 0.0714285714285714 2.77945123769758 0.305536623744418 0.671389538907637 GO:0070742 C2H2 zinc finger domain binding 1/479 14/18639 0.0714285714285714 2.77945123769758 0.305536623744418 0.671389538907637 GO:1990825 sequence-specific mRNA binding 1/479 14/18639 0.0714285714285714 2.77945123769758 0.305536623744418 0.671389538907637 GO:0051536 iron-sulfur cluster binding 3/479 76/18639 0.0394736842105263 1.53601252609603 0.310411041050769 0.679900312495071 GO:0019207 kinase regulator activity 9/479 287/18639 0.0313588850174216 1.22024688484284 0.319199590685653 0.681945672276886 GO:0008009 chemokine activity 2/479 45/18639 0.0444444444444444 1.7294363256785 0.322363129581526 0.681945672276886 GO:0000774 adenyl-nucleotide exchange factor activity 1/479 15/18639 0.0666666666666667 2.59415448851774 0.323396916749863 0.681945672276886 GO:0004089 carbonate dehydratase activity 1/479 15/18639 0.0666666666666667 2.59415448851774 0.323396916749863 0.681945672276886 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/479 15/18639 0.0666666666666667 2.59415448851774 0.323396916749863 0.681945672276886 GO:0005041 low-density lipoprotein particle receptor activity 1/479 15/18639 0.0666666666666667 2.59415448851774 0.323396916749863 0.681945672276886 GO:0005523 tropomyosin binding 1/479 15/18639 0.0666666666666667 2.59415448851774 0.323396916749863 0.681945672276886 GO:0008242 omega peptidase activity 1/479 15/18639 0.0666666666666667 2.59415448851774 0.323396916749863 0.681945672276886 GO:0016846 carbon-sulfur lyase activity 1/479 15/18639 0.0666666666666667 2.59415448851774 0.323396916749863 0.681945672276886 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/479 15/18639 0.0666666666666667 2.59415448851774 0.323396916749863 0.681945672276886 GO:0017081 chloride channel regulator activity 1/479 15/18639 0.0666666666666667 2.59415448851774 0.323396916749863 0.681945672276886 GO:0030553 cGMP binding 1/479 15/18639 0.0666666666666667 2.59415448851774 0.323396916749863 0.681945672276886 GO:0030276 clathrin binding 2/479 46/18639 0.0434782608695652 1.69183988381592 0.33182826816857 0.690753410774004 GO:0061135 endopeptidase regulator activity 6/479 184/18639 0.0326086956521739 1.26887991286194 0.335642404996388 0.690753410774004 GO:0000062 fatty-acyl-CoA binding 1/479 16/18639 0.0625 2.43201983298539 0.340798810912064 0.690753410774004 GO:0004708 MAP kinase kinase activity 1/479 16/18639 0.0625 2.43201983298539 0.340798810912064 0.690753410774004 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/479 16/18639 0.0625 2.43201983298539 0.340798810912064 0.690753410774004 GO:0005521 lamin binding 1/479 16/18639 0.0625 2.43201983298539 0.340798810912064 0.690753410774004 GO:0015562 efflux transmembrane transporter activity 1/479 16/18639 0.0625 2.43201983298539 0.340798810912064 0.690753410774004 GO:0016722 oxidoreductase activity, acting on metal ions 1/479 16/18639 0.0625 2.43201983298539 0.340798810912064 0.690753410774004 GO:0030275 LRR domain binding 1/479 16/18639 0.0625 2.43201983298539 0.340798810912064 0.690753410774004 GO:0043023 ribosomal large subunit binding 1/479 16/18639 0.0625 2.43201983298539 0.340798810912064 0.690753410774004 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/479 16/18639 0.0625 2.43201983298539 0.340798810912064 0.690753410774004 GO:0070411 I-SMAD binding 1/479 16/18639 0.0625 2.43201983298539 0.340798810912064 0.690753410774004 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/479 16/18639 0.0625 2.43201983298539 0.340798810912064 0.690753410774004 GO:0001221 transcription coregulator binding 4/479 115/18639 0.0347826086956522 1.35347190705274 0.342574554627599 0.692286079143274 GO:0038187 pattern recognition receptor activity 2/479 48/18639 0.0416666666666667 1.62134655532359 0.350640587944883 0.696370437402807 GO:0003779 actin binding 13/479 443/18639 0.0293453724604966 1.14189644528433 0.352225010076737 0.696370437402807 GO:0001664 G protein-coupled receptor binding 9/479 297/18639 0.0303030303030303 1.17916113114443 0.355186709972706 0.696370437402807 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/479 17/18639 0.0588235294117647 2.28895984280978 0.357754047424608 0.696370437402807 GO:0004659 prenyltransferase activity 1/479 17/18639 0.0588235294117647 2.28895984280978 0.357754047424608 0.696370437402807 GO:0031489 myosin V binding 1/479 17/18639 0.0588235294117647 2.28895984280978 0.357754047424608 0.696370437402807 GO:0036041 long-chain fatty acid binding 1/479 17/18639 0.0588235294117647 2.28895984280978 0.357754047424608 0.696370437402807 GO:0046965 nuclear retinoid X receptor binding 1/479 17/18639 0.0588235294117647 2.28895984280978 0.357754047424608 0.696370437402807 GO:0051787 misfolded protein binding 1/479 17/18639 0.0588235294117647 2.28895984280978 0.357754047424608 0.696370437402807 GO:0070403 NAD+ binding 1/479 17/18639 0.0588235294117647 2.28895984280978 0.357754047424608 0.696370437402807 GO:0070492 oligosaccharide binding 1/479 17/18639 0.0588235294117647 2.28895984280978 0.357754047424608 0.696370437402807 GO:1901567 fatty acid derivative binding 1/479 17/18639 0.0588235294117647 2.28895984280978 0.357754047424608 0.696370437402807 GO:0001222 transcription corepressor binding 2/479 49/18639 0.0408163265306122 1.58825785011291 0.359979416094824 0.696370437402807 GO:0016763 pentosyltransferase activity 2/479 49/18639 0.0408163265306122 1.58825785011291 0.359979416094824 0.696370437402807 GO:0060590 ATPase regulator activity 2/479 49/18639 0.0408163265306122 1.58825785011291 0.359979416094824 0.696370437402807 GO:0019902 phosphatase binding 6/479 190/18639 0.0315789473684211 1.22881002087683 0.363068248969721 0.700350400711479 GO:0015605 organophosphate ester transmembrane transporter activity 2/479 50/18639 0.04 1.55649269311065 0.36926818640112 0.702022352870565 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/479 18/18639 0.0555555555555556 2.16179540709812 0.37427406736251 0.702022352870565 GO:0004970 glutamate-gated receptor activity 1/479 18/18639 0.0555555555555556 2.16179540709812 0.37427406736251 0.702022352870565 GO:0008525 phosphatidylcholine transporter activity 1/479 18/18639 0.0555555555555556 2.16179540709812 0.37427406736251 0.702022352870565 GO:0015172 acidic amino acid transmembrane transporter activity 1/479 18/18639 0.0555555555555556 2.16179540709812 0.37427406736251 0.702022352870565 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/479 18/18639 0.0555555555555556 2.16179540709812 0.37427406736251 0.702022352870565 GO:0030228 lipoprotein particle receptor activity 1/479 18/18639 0.0555555555555556 2.16179540709812 0.37427406736251 0.702022352870565 GO:0031690 adrenergic receptor binding 1/479 18/18639 0.0555555555555556 2.16179540709812 0.37427406736251 0.702022352870565 GO:0050811 GABA receptor binding 1/479 18/18639 0.0555555555555556 2.16179540709812 0.37427406736251 0.702022352870565 GO:1901611 phosphatidylglycerol binding 1/479 18/18639 0.0555555555555556 2.16179540709812 0.37427406736251 0.702022352870565 GO:0005048 signal sequence binding 2/479 51/18639 0.0392156862745098 1.52597322853985 0.378503306127821 0.703080220505095 GO:0030544 Hsp70 protein binding 2/479 51/18639 0.0392156862745098 1.52597322853985 0.378503306127821 0.703080220505095 GO:0005525 GTP binding 11/479 378/18639 0.0291005291005291 1.13236902276568 0.38036370779662 0.703080220505095 GO:0050660 flavin adenine dinucleotide binding 3/479 86/18639 0.0348837209302326 1.35740641841045 0.380831536671536 0.703080220505095 GO:0008236 serine-type peptidase activity 6/479 194/18639 0.0309278350515464 1.20347373178658 0.381424921710912 0.703080220505095 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/479 122/18639 0.0327868852459016 1.27581368287758 0.383505160351676 0.703080220505095 GO:0003756 protein disulfide isomerase activity 1/479 19/18639 0.0526315789473684 2.04801670146138 0.39037001933788 0.703080220505095 GO:0005520 insulin-like growth factor binding 1/479 19/18639 0.0526315789473684 2.04801670146138 0.39037001933788 0.703080220505095 GO:0015245 fatty acid transmembrane transporter activity 1/479 19/18639 0.0526315789473684 2.04801670146138 0.39037001933788 0.703080220505095 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/479 19/18639 0.0526315789473684 2.04801670146138 0.39037001933788 0.703080220505095 GO:0031420 alkali metal ion binding 1/479 19/18639 0.0526315789473684 2.04801670146138 0.39037001933788 0.703080220505095 GO:0043395 heparan sulfate proteoglycan binding 1/479 19/18639 0.0526315789473684 2.04801670146138 0.39037001933788 0.703080220505095 GO:0046624 sphingolipid transporter activity 1/479 19/18639 0.0526315789473684 2.04801670146138 0.39037001933788 0.703080220505095 GO:0097001 ceramide binding 1/479 19/18639 0.0526315789473684 2.04801670146138 0.39037001933788 0.703080220505095 GO:0120227 acyl-CoA binding 1/479 19/18639 0.0526315789473684 2.04801670146138 0.39037001933788 0.703080220505095 GO:0038064 collagen receptor activity 2/479 53/18639 0.0377358490566038 1.46838933312325 0.396799298655827 0.710888453264661 GO:1901505 carbohydrate derivative transmembrane transporter activity 2/479 53/18639 0.0377358490566038 1.46838933312325 0.396799298655827 0.710888453264661 GO:0004866 endopeptidase inhibitor activity 5/479 161/18639 0.031055900621118 1.20845705986851 0.398442024688092 0.711952986218985 GO:0017171 serine hydrolase activity 6/479 198/18639 0.0303030303030303 1.17916113114443 0.399791477502509 0.712428498104198 GO:0050661 NADP binding 2/479 54/18639 0.037037037037037 1.44119693806541 0.405854035842423 0.712428498104198 GO:0001614 purinergic nucleotide receptor activity 1/479 20/18639 0.05 1.94561586638831 0.406052766960713 0.712428498104198 GO:0010851 cyclase regulator activity 1/479 20/18639 0.05 1.94561586638831 0.406052766960713 0.712428498104198 GO:0015095 magnesium ion transmembrane transporter activity 1/479 20/18639 0.05 1.94561586638831 0.406052766960713 0.712428498104198 GO:0016502 nucleotide receptor activity 1/479 20/18639 0.05 1.94561586638831 0.406052766960713 0.712428498104198 GO:0031418 L-ascorbic acid binding 1/479 20/18639 0.05 1.94561586638831 0.406052766960713 0.712428498104198 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 10/479 349/18639 0.0286532951289398 1.11496611254344 0.408354943772688 0.714621151602203 GO:0031490 chromatin DNA binding 4/479 128/18639 0.03125 1.21600991649269 0.418359601240373 0.724263493882068 GO:0001846 opsonin binding 1/479 21/18639 0.0476190476190476 1.85296749179839 0.421332896109745 0.724263493882068 GO:0005123 death receptor binding 1/479 21/18639 0.0476190476190476 1.85296749179839 0.421332896109745 0.724263493882068 GO:0010314 phosphatidylinositol-5-phosphate binding 1/479 21/18639 0.0476190476190476 1.85296749179839 0.421332896109745 0.724263493882068 GO:0035613 RNA stem-loop binding 1/479 21/18639 0.0476190476190476 1.85296749179839 0.421332896109745 0.724263493882068 GO:0070182 DNA polymerase binding 1/479 21/18639 0.0476190476190476 1.85296749179839 0.421332896109745 0.724263493882068 GO:0072542 protein phosphatase activator activity 1/479 21/18639 0.0476190476190476 1.85296749179839 0.421332896109745 0.724263493882068 GO:0043178 alcohol binding 3/479 92/18639 0.0326086956521739 1.26887991286194 0.422398149598378 0.724263493882068 GO:0051219 phosphoprotein binding 3/479 93/18639 0.032258064516129 1.25523604283117 0.429239023060218 0.734139286291909 GO:0015932 nucleobase-containing compound transmembrane transporter activity 2/479 57/18639 0.0350877192982456 1.36534446764092 0.432612422923704 0.734972382755214 GO:0005243 gap junction channel activity 1/479 22/18639 0.0454545454545455 1.76874169671664 0.43622072201819 0.734972382755214 GO:0031683 G-protein beta/gamma-subunit complex binding 1/479 22/18639 0.0454545454545455 1.76874169671664 0.43622072201819 0.734972382755214 GO:0061133 endopeptidase activator activity 1/479 22/18639 0.0454545454545455 1.76874169671664 0.43622072201819 0.734972382755214 GO:0070034 telomerase RNA binding 1/479 22/18639 0.0454545454545455 1.76874169671664 0.43622072201819 0.734972382755214 GO:0140517 protein-RNA adaptor activity 1/479 22/18639 0.0454545454545455 1.76874169671664 0.43622072201819 0.734972382755214 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 4/479 132/18639 0.0303030303030303 1.17916113114443 0.441347892616626 0.74000697371518 GO:0061980 regulatory RNA binding 2/479 58/18639 0.0344827586206897 1.34180404578504 0.441388548386816 0.74000697371518 GO:0051015 actin filament binding 6/479 209/18639 0.0287081339712919 1.11710001897893 0.450033132836585 0.750105772317636 GO:0070888 E-box binding 2/479 59/18639 0.0338983050847458 1.31906160433106 0.45008939312095 0.750105772317636 GO:0140103 catalytic activity, acting on a glycoprotein 1/479 23/18639 0.0434782608695652 1.69183988381592 0.45072629617908 0.750105772317636 GO:0015297 antiporter activity 4/479 135/18639 0.0296296296296296 1.15295755045233 0.458412019149143 0.753316328109239 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 2/479 60/18639 0.0333333333333333 1.29707724425887 0.458713026376119 0.753316328109239 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/479 24/18639 0.0416666666666667 1.62134655532359 0.464859413074773 0.753316328109239 GO:0004622 lysophospholipase activity 1/479 24/18639 0.0416666666666667 1.62134655532359 0.464859413074773 0.753316328109239 GO:0005315 phosphate transmembrane transporter activity 1/479 24/18639 0.0416666666666667 1.62134655532359 0.464859413074773 0.753316328109239 GO:0005540 hyaluronic acid binding 1/479 24/18639 0.0416666666666667 1.62134655532359 0.464859413074773 0.753316328109239 GO:0015295 solute:proton symporter activity 1/479 24/18639 0.0416666666666667 1.62134655532359 0.464859413074773 0.753316328109239 GO:0035035 histone acetyltransferase binding 1/479 24/18639 0.0416666666666667 1.62134655532359 0.464859413074773 0.753316328109239 GO:0050431 transforming growth factor beta binding 1/479 24/18639 0.0416666666666667 1.62134655532359 0.464859413074773 0.753316328109239 GO:0050699 WW domain binding 1/479 24/18639 0.0416666666666667 1.62134655532359 0.464859413074773 0.753316328109239 GO:0070300 phosphatidic acid binding 1/479 24/18639 0.0416666666666667 1.62134655532359 0.464859413074773 0.753316328109239 GO:0016922 nuclear receptor binding 4/479 137/18639 0.0291970802919708 1.13612605336544 0.469689691155403 0.759331667367901 GO:0005537 D-mannose binding 1/479 25/18639 0.04 1.55649269311065 0.478629616735111 0.764681199442682 GO:0008483 transaminase activity 1/479 25/18639 0.04 1.55649269311065 0.478629616735111 0.764681199442682 GO:0019211 phosphatase activator activity 1/479 25/18639 0.04 1.55649269311065 0.478629616735111 0.764681199442682 GO:0042974 nuclear retinoic acid receptor binding 1/479 25/18639 0.04 1.55649269311065 0.478629616735111 0.764681199442682 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/479 25/18639 0.04 1.55649269311065 0.478629616735111 0.764681199442682 GO:0019887 protein kinase regulator activity 7/479 255/18639 0.0274509803921569 1.0681812599779 0.483541053194136 0.768005380419046 GO:0005319 lipid transporter activity 5/479 178/18639 0.0280898876404494 1.09304262156647 0.483862529522502 0.768005380419046 GO:1901682 sulfur compound transmembrane transporter activity 2/479 63/18639 0.0317460317460317 1.23531166119893 0.484103538761931 0.768005380419046 GO:0140297 DNA-binding transcription factor binding 13/479 488/18639 0.0266393442622951 1.03659861733803 0.487241206101195 0.768044539402989 GO:0008066 glutamate receptor activity 1/479 26/18639 0.0384615384615385 1.49662758952947 0.492046207128572 0.768044539402989 GO:0008157 protein phosphatase 1 binding 1/479 26/18639 0.0384615384615385 1.49662758952947 0.492046207128572 0.768044539402989 GO:0030247 polysaccharide binding 1/479 26/18639 0.0384615384615385 1.49662758952947 0.492046207128572 0.768044539402989 GO:0043548 phosphatidylinositol 3-kinase binding 1/479 26/18639 0.0384615384615385 1.49662758952947 0.492046207128572 0.768044539402989 GO:0070006 metalloaminopeptidase activity 1/479 26/18639 0.0384615384615385 1.49662758952947 0.492046207128572 0.768044539402989 GO:0070412 R-SMAD binding 1/479 26/18639 0.0384615384615385 1.49662758952947 0.492046207128572 0.768044539402989 GO:0008395 steroid hydroxylase activity 1/479 27/18639 0.037037037037037 1.44119693806541 0.505118246390669 0.784840478945685 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/479 27/18639 0.037037037037037 1.44119693806541 0.505118246390669 0.784840478945685 GO:0019903 protein phosphatase binding 4/479 144/18639 0.0277777777777778 1.08089770354906 0.508435421451902 0.786629193652883 GO:0008235 metalloexopeptidase activity 2/479 66/18639 0.0303030303030303 1.17916113114443 0.508743188953768 0.786629193652883 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 2/479 67/18639 0.0298507462686567 1.1615617112766 0.51678398127172 0.786629193652883 GO:0016866 intramolecular transferase activity 1/479 28/18639 0.0357142857142857 1.38972561884879 0.517854564893724 0.786629193652883 GO:0019789 SUMO transferase activity 1/479 28/18639 0.0357142857142857 1.38972561884879 0.517854564893724 0.786629193652883 GO:0046625 sphingolipid binding 1/479 28/18639 0.0357142857142857 1.38972561884879 0.517854564893724 0.786629193652883 GO:0046875 ephrin receptor binding 1/479 28/18639 0.0357142857142857 1.38972561884879 0.517854564893724 0.786629193652883 GO:0051019 mitogen-activated protein kinase binding 1/479 28/18639 0.0357142857142857 1.38972561884879 0.517854564893724 0.786629193652883 GO:0051537 2 iron, 2 sulfur cluster binding 1/479 28/18639 0.0357142857142857 1.38972561884879 0.517854564893724 0.786629193652883 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/479 28/18639 0.0357142857142857 1.38972561884879 0.517854564893724 0.786629193652883 GO:0005548 phospholipid transporter activity 2/479 68/18639 0.0294117647058824 1.14447992140489 0.524736956407435 0.795304449555019 GO:0005496 steroid binding 3/479 108/18639 0.0277777777777778 1.08089770354906 0.527633236711132 0.797913068433984 GO:0004181 metallocarboxypeptidase activity 1/479 29/18639 0.0344827586206897 1.34180404578504 0.530263767162055 0.80010910645119 GO:0008514 organic anion transmembrane transporter activity 7/479 269/18639 0.0260223048327138 1.01258818325042 0.540024292441106 0.80935940078062 GO:0019842 vitamin binding 4/479 150/18639 0.0266666666666667 1.0376617954071 0.540603450989573 0.80935940078062 GO:0001968 fibronectin binding 1/479 30/18639 0.0333333333333333 1.29707724425887 0.542354237636498 0.80935940078062 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/479 30/18639 0.0333333333333333 1.29707724425887 0.542354237636498 0.80935940078062 GO:0031210 phosphatidylcholine binding 1/479 30/18639 0.0333333333333333 1.29707724425887 0.542354237636498 0.80935940078062 GO:1902936 phosphatidylinositol bisphosphate binding 3/479 111/18639 0.027027027027027 1.05168425210179 0.546176565194902 0.813276069665215 GO:0140299 molecular sensor activity 2/479 71/18639 0.028169014084507 1.09612161486665 0.548061425643387 0.814296954074092 GO:0046906 tetrapyrrole binding 4/479 152/18639 0.0263157894736842 1.02400835073069 0.551086679667451 0.815798577355995 GO:0005184 neuropeptide hormone activity 1/479 31/18639 0.032258064516129 1.25523604283117 0.554134146292101 0.815798577355995 GO:0017147 Wnt-protein binding 1/479 31/18639 0.032258064516129 1.25523604283117 0.554134146292101 0.815798577355995 GO:0070273 phosphatidylinositol-4-phosphate binding 1/479 31/18639 0.032258064516129 1.25523604283117 0.554134146292101 0.815798577355995 GO:0042379 chemokine receptor binding 2/479 72/18639 0.0277777777777778 1.08089770354906 0.555656056249788 0.815798577355995 GO:0003774 cytoskeletal motor activity 4/479 153/18639 0.0261437908496732 1.01731548569323 0.556280915045398 0.815798577355995 GO:0051020 GTPase binding 8/479 315/18639 0.0253968253968254 0.988249328959141 0.563479721118148 0.822377253410144 GO:0030515 snoRNA binding 1/479 32/18639 0.03125 1.21600991649269 0.56561145411272 0.822377253410144 GO:0031369 translation initiation factor binding 1/479 32/18639 0.03125 1.21600991649269 0.56561145411272 0.822377253410144 GO:0160041 neuropeptide activity 1/479 32/18639 0.03125 1.21600991649269 0.56561145411272 0.822377253410144 GO:0140311 protein sequestering activity 1/479 33/18639 0.0303030303030303 1.17916113114443 0.576793918426151 0.834871320707988 GO:0140416 transcription regulator inhibitor activity 1/479 33/18639 0.0303030303030303 1.17916113114443 0.576793918426151 0.834871320707988 GO:0003725 double-stranded RNA binding 2/479 75/18639 0.0266666666666667 1.0376617954071 0.577893255865618 0.834871320707988 GO:0030246 carbohydrate binding 7/479 280/18639 0.025 0.972807933194154 0.582569754207206 0.839840473687246 GO:0030332 cyclin binding 1/479 34/18639 0.0294117647058824 1.14447992140489 0.587689098103345 0.845425630534261 GO:0005154 epidermal growth factor receptor binding 1/479 35/18639 0.0285714285714286 1.11178049507903 0.598304358625167 0.85706468250314 GO:0043015 gamma-tubulin binding 1/479 35/18639 0.0285714285714286 1.11178049507903 0.598304358625167 0.85706468250314 GO:0004033 aldo-keto reductase (NADPH) activity 1/479 36/18639 0.0277777777777778 1.08089770354906 0.608646877020057 0.866396707540082 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/479 36/18639 0.0277777777777778 1.08089770354906 0.608646877020057 0.866396707540082 GO:0005484 SNAP receptor activity 1/479 36/18639 0.0277777777777778 1.08089770354906 0.608646877020057 0.866396707540082 GO:0000049 tRNA binding 2/479 80/18639 0.025 0.972807933194154 0.613120670211797 0.870939194715084 GO:0022829 wide pore channel activity 1/479 37/18639 0.027027027027027 1.05168425210179 0.618723646675887 0.875236158526931 GO:0030551 cyclic nucleotide binding 1/479 37/18639 0.027027027027027 1.05168425210179 0.618723646675887 0.875236158526931 GO:0000146 microfilament motor activity 1/479 38/18639 0.0263157894736842 1.02400835073069 0.628541482029196 0.881776170036826 GO:0005501 retinoid binding 1/479 38/18639 0.0263157894736842 1.02400835073069 0.628541482029196 0.881776170036826 GO:0019840 isoprenoid binding 1/479 38/18639 0.0263157894736842 1.02400835073069 0.628541482029196 0.881776170036826 GO:0042887 amide transmembrane transporter activity 1/479 38/18639 0.0263157894736842 1.02400835073069 0.628541482029196 0.881776170036826 GO:0042826 histone deacetylase binding 3/479 127/18639 0.0236220472440945 0.919188598293689 0.637465601281941 0.89151166400952 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/479 39/18639 0.0256410256410256 0.997751726352979 0.638107023134943 0.89151166400952 GO:0051117 ATPase binding 2/479 84/18639 0.0238095238095238 0.926483745899195 0.639652185028723 0.891835387339841 GO:0071855 neuropeptide receptor binding 1/479 40/18639 0.025 0.972807933194154 0.647426740119802 0.89784418231928 GO:0140662 ATP-dependent protein folding chaperone 1/479 40/18639 0.025 0.972807933194154 0.647426740119802 0.89784418231928 GO:0035591 signaling adaptor activity 3/479 129/18639 0.0232558139534884 0.904937612273632 0.647928791364429 0.89784418231928 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 2/479 86/18639 0.0232558139534884 0.904937612273632 0.652372369991129 0.900494132552824 GO:0005261 monoatomic cation channel activity 8/479 341/18639 0.0234604105571848 0.912898940240849 0.652493539346082 0.900494132552824 GO:0017080 sodium channel regulator activity 1/479 41/18639 0.024390243902439 0.949080910433321 0.656506937521953 0.900541839550315 GO:0042169 SH2 domain binding 1/479 41/18639 0.024390243902439 0.949080910433321 0.656506937521953 0.900541839550315 GO:0061650 ubiquitin-like protein conjugating enzyme activity 1/479 41/18639 0.024390243902439 0.949080910433321 0.656506937521953 0.900541839550315 GO:0031072 heat shock protein binding 3/479 131/18639 0.0229007633587786 0.891121770864874 0.658176059039514 0.901011177596432 GO:0015631 tubulin binding 9/479 385/18639 0.0233766233766234 0.909638586882846 0.660232674957305 0.901746910250048 GO:0004197 cysteine-type endopeptidase activity 2/479 88/18639 0.0227272727272727 0.884370848358322 0.66473269752724 0.901746910250048 GO:0004520 DNA endonuclease activity 1/479 42/18639 0.0238095238095238 0.926483745899195 0.665353758520286 0.901746910250048 GO:0019894 kinesin binding 1/479 42/18639 0.0238095238095238 0.926483745899195 0.665353758520286 0.901746910250048 GO:0042056 chemoattractant activity 1/479 42/18639 0.0238095238095238 0.926483745899195 0.665353758520286 0.901746910250048 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/479 43/18639 0.0232558139534884 0.904937612273632 0.67397318905579 0.909796809878492 GO:0008375 acetylglucosaminyltransferase activity 1/479 43/18639 0.0232558139534884 0.904937612273632 0.67397318905579 0.909796809878492 GO:0001223 transcription coactivator binding 1/479 44/18639 0.0227272727272727 0.884370848358322 0.682371061847911 0.915988017108786 GO:0043014 alpha-tubulin binding 1/479 44/18639 0.0227272727272727 0.884370848358322 0.682371061847911 0.915988017108786 GO:0072341 modified amino acid binding 2/479 91/18639 0.021978021978022 0.855215765445411 0.682606681380038 0.915988017108786 GO:0051539 4 iron, 4 sulfur cluster binding 1/479 45/18639 0.0222222222222222 0.864718162839248 0.690553060308511 0.924823526527572 GO:0004180 carboxypeptidase activity 1/479 46/18639 0.0217391304347826 0.84591994190796 0.698524722356065 0.931761603458146 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/479 46/18639 0.0217391304347826 0.84591994190796 0.698524722356065 0.931761603458146 GO:1901981 phosphatidylinositol phosphate binding 4/479 185/18639 0.0216216216216216 0.841347401681431 0.703640946313714 0.931761603458146 GO:0004867 serine-type endopeptidase inhibitor activity 2/479 95/18639 0.0210526315789474 0.819206680584551 0.705218047537169 0.931761603458146 GO:0001784 phosphotyrosine residue binding 1/479 47/18639 0.0212765957446809 0.827921645271621 0.706291444132618 0.931761603458146 GO:0043495 protein-membrane adaptor activity 1/479 47/18639 0.0212765957446809 0.827921645271621 0.706291444132618 0.931761603458146 GO:0000287 magnesium ion binding 5/479 230/18639 0.0217391304347826 0.84591994190796 0.707873176155575 0.931761603458146 GO:0005085 guanyl-nucleotide exchange factor activity 5/479 230/18639 0.0217391304347826 0.84591994190796 0.707873176155575 0.931761603458146 GO:0020037 heme binding 3/479 142/18639 0.0211267605633803 0.82209121114999 0.710674693064952 0.931761603458146 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1/479 48/18639 0.0208333333333333 0.810673277661795 0.713858483625974 0.931761603458146 GO:0032266 phosphatidylinositol-3-phosphate binding 1/479 48/18639 0.0208333333333333 0.810673277661795 0.713858483625974 0.931761603458146 GO:0140693 molecular condensate scaffold activity 1/479 48/18639 0.0208333333333333 0.810673277661795 0.713858483625974 0.931761603458146 GO:0046943 carboxylic acid transmembrane transporter activity 4/479 188/18639 0.0212765957446809 0.827921645271621 0.715458092006473 0.931761603458146 GO:0030594 neurotransmitter receptor activity 2/479 97/18639 0.0206185567010309 0.802315821191055 0.716012073317527 0.931761603458146 GO:0008017 microtubule binding 6/479 276/18639 0.0217391304347826 0.84591994190796 0.716317462452359 0.931761603458146 GO:0005342 organic acid transmembrane transporter activity 4/479 189/18639 0.0211640211640212 0.823541107465951 0.719319511460455 0.932359060068447 GO:0019955 cytokine binding 3/479 144/18639 0.0208333333333333 0.810673277661795 0.719523044883455 0.932359060068447 GO:0035254 glutamate receptor binding 1/479 49/18639 0.0204081632653061 0.794128925056453 0.721230964199539 0.932792047031404 GO:0032813 tumor necrosis factor receptor superfamily binding 1/479 50/18639 0.02 0.778246346555324 0.72841387803216 0.938506685358324 GO:0048020 CCR chemokine receptor binding 1/479 50/18639 0.02 0.778246346555324 0.72841387803216 0.938506685358324 GO:0015171 amino acid transmembrane transporter activity 2/479 102/18639 0.0196078431372549 0.762986614269925 0.741550672948013 0.950895093777192 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/479 52/18639 0.0192307692307692 0.748313794764734 0.742230338294421 0.950895093777192 GO:0030159 signaling receptor complex adaptor activity 1/479 52/18639 0.0192307692307692 0.748313794764734 0.742230338294421 0.950895093777192 GO:0004864 protein phosphatase inhibitor activity 1/479 53/18639 0.0188679245283019 0.734194666561626 0.748873242902856 0.952218973653631 GO:0051018 protein kinase A binding 1/479 53/18639 0.0188679245283019 0.734194666561626 0.748873242902856 0.952218973653631 GO:0140296 general transcription initiation factor binding 1/479 53/18639 0.0188679245283019 0.734194666561626 0.748873242902856 0.952218973653631 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/479 53/18639 0.0188679245283019 0.734194666561626 0.748873242902856 0.952218973653631 GO:0140463 chromatin-protein adaptor activity 1/479 54/18639 0.0185185185185185 0.720598469032707 0.75534530341343 0.958653198163961 GO:0008013 beta-catenin binding 2/479 106/18639 0.0188679245283019 0.734194666561626 0.760545130060467 0.963451759908689 GO:0019888 protein phosphatase regulator activity 2/479 107/18639 0.0186915887850467 0.727333034163854 0.765101046643142 0.965430264418148 GO:0019212 phosphatase inhibitor activity 1/479 56/18639 0.0178571428571429 0.694862809424396 0.767794319272165 0.965430264418148 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/479 56/18639 0.0178571428571429 0.694862809424396 0.767794319272165 0.965430264418148 GO:0170055 lipid transmembrane transporter activity 1/479 56/18639 0.0178571428571429 0.694862809424396 0.767794319272165 0.965430264418148 GO:0140104 molecular carrier activity 5/479 249/18639 0.0200803212851406 0.781371833890887 0.770302379938783 0.966793560034073 GO:0031593 polyubiquitin modification-dependent protein binding 1/479 59/18639 0.0169491525423729 0.659530802165529 0.785292543499675 0.980172126904925 GO:0045309 protein phosphorylated amino acid binding 1/479 59/18639 0.0169491525423729 0.659530802165529 0.785292543499675 0.980172126904925 GO:0070063 RNA polymerase binding 1/479 59/18639 0.0169491525423729 0.659530802165529 0.785292543499675 0.980172126904925 GO:0001098 basal transcription machinery binding 1/479 60/18639 0.0166666666666667 0.648538622129436 0.790827789552617 0.983465328033382 GO:0001099 basal RNA polymerase II transcription machinery binding 1/479 60/18639 0.0166666666666667 0.648538622129436 0.790827789552617 0.983465328033382 GO:0015026 coreceptor activity 1/479 61/18639 0.0163934426229508 0.63790684143879 0.796220624947648 0.984496819714862 GO:0019905 syntaxin binding 1/479 61/18639 0.0163934426229508 0.63790684143879 0.796220624947648 0.984496819714862 GO:0017124 SH3 domain binding 2/479 115/18639 0.0173913043478261 0.676735953526368 0.798906844864343 0.984496819714862 GO:0035401 histone H3Y41 kinase activity 2/479 115/18639 0.0173913043478261 0.676735953526368 0.798906844864343 0.984496819714862 GO:0140801 histone H2AXY142 kinase activity 2/479 115/18639 0.0173913043478261 0.676735953526368 0.798906844864343 0.984496819714862 GO:0015179 L-amino acid transmembrane transporter activity 1/479 62/18639 0.0161290322580645 0.627618021415584 0.801474706153918 0.98510751566583 GO:0022824 transmitter-gated monoatomic ion channel activity 1/479 63/18639 0.0158730158730159 0.617655830599463 0.806593595950563 0.98510751566583 GO:0022835 transmitter-gated channel activity 1/479 63/18639 0.0158730158730159 0.617655830599463 0.806593595950563 0.98510751566583 GO:0019208 phosphatase regulator activity 2/479 117/18639 0.0170940170940171 0.665167817568653 0.806656522400886 0.98510751566583 GO:1990782 protein tyrosine kinase binding 2/479 117/18639 0.0170940170940171 0.665167817568653 0.806656522400886 0.98510751566583 GO:0004536 DNA nuclease activity 1/479 64/18639 0.015625 0.608004958246347 0.811580765822424 0.989341723507048 GO:0005216 monoatomic ion channel activity 9/479 448/18639 0.0200892857142857 0.781720660602446 0.817156170850952 0.994353118293542 GO:0004175 endopeptidase activity 8/479 405/18639 0.0197530864197531 0.768638366968221 0.8207625468117 0.9959026351872 GO:0003697 single-stranded DNA binding 2/479 121/18639 0.0165289256198347 0.643178798806053 0.821362998092536 0.9959026351872 GO:0003823 antigen binding 3/479 174/18639 0.0172413793103448 0.67090202289252 0.828172975654665 0.9999976389434 GO:0003777 microtubule motor activity 1/479 68/18639 0.0147058823529412 0.572239960702444 0.830278609538729 0.9999976389434 GO:1990841 promoter-specific chromatin binding 1/479 68/18639 0.0147058823529412 0.572239960702444 0.830278609538729 0.9999976389434 GO:0098960 postsynaptic neurotransmitter receptor activity 1/479 69/18639 0.0144927536231884 0.56394662793864 0.834656216885181 0.9999976389434 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/479 70/18639 0.0142857142857143 0.555890247539517 0.838921142685504 0.9999976389434 GO:0004519 endonuclease activity 2/479 127/18639 0.015748031496063 0.61279239886246 0.841545615006193 0.9999976389434 GO:0019783 ubiquitin-like protein peptidase activity 2/479 127/18639 0.015748031496063 0.61279239886246 0.841545615006193 0.9999976389434 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 2/479 130/18639 0.0153846153846154 0.598651035811787 0.850842807522631 0.9999976389434 GO:0004521 RNA endonuclease activity 1/479 73/18639 0.0136986301369863 0.533045442846112 0.851068407297399 0.9999976389434 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/479 73/18639 0.0136986301369863 0.533045442846112 0.851068407297399 0.9999976389434 GO:0003684 damaged DNA binding 1/479 74/18639 0.0135135135135135 0.525842126050894 0.854910819928259 0.9999976389434 GO:0005179 hormone activity 2/479 132/18639 0.0151515151515152 0.589580565572215 0.856762370653796 0.9999976389434 GO:0035091 phosphatidylinositol binding 5/479 284/18639 0.0176056338028169 0.685076009291658 0.857957151739961 0.9999976389434 GO:0008234 cysteine-type peptidase activity 3/479 187/18639 0.0160427807486631 0.624261775311757 0.862748279673024 0.9999976389434 GO:0015291 secondary active transmembrane transporter activity 5/479 287/18639 0.0174216027874564 0.677914936023801 0.863971483983003 0.9999976389434 GO:0016779 nucleotidyltransferase activity 2/479 136/18639 0.0147058823529412 0.572239960702444 0.867962728349146 0.9999976389434 GO:0004713 protein tyrosine kinase activity 2/479 140/18639 0.0142857142857143 0.555890247539517 0.878354398289338 0.9999976389434 GO:0030971 receptor tyrosine kinase binding 1/479 81/18639 0.0123456790123457 0.480398979355138 0.87917549537704 0.9999976389434 GO:0033192 calmodulin-dependent protein phosphatase activity 1/479 81/18639 0.0123456790123457 0.480398979355138 0.87917549537704 0.9999976389434 GO:0140791 histone H2AXS140 phosphatase activity 1/479 81/18639 0.0123456790123457 0.480398979355138 0.87917549537704 0.9999976389434 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/479 81/18639 0.0123456790123457 0.480398979355138 0.87917549537704 0.9999976389434 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/479 81/18639 0.0123456790123457 0.480398979355138 0.87917549537704 0.9999976389434 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/479 81/18639 0.0123456790123457 0.480398979355138 0.87917549537704 0.9999976389434 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/479 81/18639 0.0123456790123457 0.480398979355138 0.87917549537704 0.9999976389434 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/479 81/18639 0.0123456790123457 0.480398979355138 0.87917549537704 0.9999976389434 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/479 81/18639 0.0123456790123457 0.480398979355138 0.87917549537704 0.9999976389434 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/479 82/18639 0.0121951219512195 0.474540455216661 0.882294093163138 0.9999976389434 GO:0033549 MAP kinase phosphatase activity 1/479 82/18639 0.0121951219512195 0.474540455216661 0.882294093163138 0.9999976389434 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/479 83/18639 0.0120481927710843 0.468823100334532 0.885332360629585 0.9999976389434 GO:0030165 PDZ domain binding 1/479 83/18639 0.0120481927710843 0.468823100334532 0.885332360629585 0.9999976389434 GO:0004527 exonuclease activity 1/479 84/18639 0.0119047619047619 0.463241872949597 0.888292362745258 0.9999976389434 GO:0004860 protein kinase inhibitor activity 1/479 84/18639 0.0119047619047619 0.463241872949597 0.888292362745258 0.9999976389434 GO:0017018 myosin phosphatase activity 1/479 84/18639 0.0119047619047619 0.463241872949597 0.888292362745258 0.9999976389434 GO:0008194 UDP-glycosyltransferase activity 2/479 145/18639 0.0137931034482759 0.536721618314016 0.89028276356435 0.9999976389434 GO:0008081 phosphoric diester hydrolase activity 1/479 87/18639 0.0114942528735632 0.44726801526168 0.896722640174767 0.9999976389434 GO:0005516 calmodulin binding 3/479 207/18639 0.0144927536231884 0.56394662793864 0.904042913083376 0.9999976389434 GO:0019210 kinase inhibitor activity 1/479 90/18639 0.0111111111111111 0.432359081419624 0.904517934655416 0.9999976389434 GO:0004518 nuclease activity 3/479 209/18639 0.0143540669856459 0.558550009489467 0.907485847433609 0.9999976389434 GO:0003730 mRNA 3'-UTR binding 4/479 262/18639 0.0152671755725191 0.594081180576583 0.907704636737184 0.9999976389434 GO:0052689 carboxylic ester hydrolase activity 1/479 92/18639 0.0108695652173913 0.42295997095398 0.90938575285231 0.9999976389434 GO:0140375 immune receptor activity 2/479 156/18639 0.0128205128205128 0.498875863176489 0.912804357411865 0.9999976389434 GO:0016757 glycosyltransferase activity 4/479 267/18639 0.0149812734082397 0.582956064835448 0.915074772109569 0.9999976389434 GO:0046982 protein heterodimerization activity 6/479 369/18639 0.016260162601626 0.632720606955548 0.915590041460575 0.9999976389434 GO:0008276 protein methyltransferase activity 1/479 95/18639 0.0105263157894737 0.409603340292276 0.916227041368021 0.9999976389434 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 4/479 268/18639 0.0149253731343284 0.580780855638301 0.91648432411028 0.9999976389434 GO:0030527 structural constituent of chromatin 1/479 98/18639 0.0102040816326531 0.397064462528226 0.922552815781132 0.9999976389434 GO:0043130 ubiquitin binding 1/479 100/18639 0.01 0.389123173277662 0.926502870200941 0.9999976389434 GO:0001217 DNA-binding transcription repressor activity 4/479 278/18639 0.0143884892086331 0.55988945795347 0.929471099335413 0.9999976389434 GO:0004722 protein serine/threonine phosphatase activity 1/479 103/18639 0.00970873786407767 0.377789488619089 0.932054165044299 0.9999976389434 GO:0000149 SNARE binding 1/479 106/18639 0.00943396226415094 0.367097333280813 0.937186975304621 0.9999976389434 GO:0004843 cysteine-type deubiquitinase activity 1/479 108/18639 0.00925925925925926 0.360299234516353 0.940392005556225 0.9999976389434 GO:0004721 phosphoprotein phosphatase activity 2/479 175/18639 0.0114285714285714 0.444712198031613 0.941821871200322 0.9999976389434 GO:0004620 phospholipase activity 1/479 109/18639 0.00917431192660551 0.356993736951983 0.941932787453509 0.9999976389434 GO:0004222 metalloendopeptidase activity 1/479 110/18639 0.00909090909090909 0.353748339343329 0.943433823330992 0.9999976389434 GO:0101005 deubiquitinase activity 1/479 115/18639 0.00869565217391304 0.338367976763184 0.950377718374177 0.9999976389434 GO:0015294 solute:monoatomic cation symporter activity 1/479 116/18639 0.00862068965517241 0.33545101144626 0.951660868498274 0.9999976389434 GO:0008237 metallopeptidase activity 2/479 184/18639 0.0108695652173913 0.42295997095398 0.952116012771001 0.9999976389434 GO:0045182 translation regulator activity 5/479 356/18639 0.0140449438202247 0.546521310783233 0.953395466865132 0.9999976389434 GO:0032182 ubiquitin-like protein binding 1/479 120/18639 0.00833333333333333 0.324269311064718 0.956470760953114 0.9999976389434 GO:0004540 RNA nuclease activity 1/479 121/18639 0.00826446280991736 0.321589399403026 0.957596658976952 0.9999976389434 GO:0016887 ATP hydrolysis activity 6/479 417/18639 0.0143884892086331 0.55988945795347 0.959150812989676 0.9999976389434 GO:0016758 hexosyltransferase activity 2/479 197/18639 0.0101522842639594 0.395048906880875 0.963967180984845 0.9999976389434 GO:0016298 lipase activity 1/479 130/18639 0.00769230769230769 0.299325517905894 0.966507847504272 0.9999976389434 GO:0016798 hydrolase activity, acting on glycosyl bonds 1/479 130/18639 0.00769230769230769 0.299325517905894 0.966507847504272 0.9999976389434 GO:0140789 histone phosphatase activity 1/479 136/18639 0.00735294117647059 0.286119980351222 0.971383907206932 0.9999976389434 GO:0016791 phosphatase activity 3/479 273/18639 0.010989010989011 0.427607882722705 0.972914865633552 0.9999976389434 GO:0005543 phospholipid binding 7/479 497/18639 0.0140845070422535 0.548060807433327 0.973413803040771 0.9999976389434 GO:0070851 growth factor receptor binding 1/479 139/18639 0.00719424460431655 0.279944728976735 0.973549398436228 0.9999976389434 GO:0015293 symporter activity 1/479 146/18639 0.00684931506849315 0.266522721423056 0.977987338523445 0.9999976389434 GO:0042578 phosphoric ester hydrolase activity 4/479 363/18639 0.0110192837465565 0.428785865870702 0.984871036558137 0.9999976389434 GO:0015103 inorganic anion transmembrane transporter activity 1/479 165/18639 0.00606060606060606 0.235832226228886 0.986633469717875 0.9999976389434 GO:0035402 histone H3T11 kinase activity 2/479 247/18639 0.00809716599190283 0.31507949253252 0.988265631849321 0.9999976389434 GO:0042393 histone binding 2/479 247/18639 0.00809716599190283 0.31507949253252 0.988265631849321 0.9999976389434 GO:0016755 aminoacyltransferase activity 6/479 496/18639 0.0120967741935484 0.470713516061688 0.988945836120069 0.9999976389434 GO:0140030 modification-dependent protein binding 1/479 173/18639 0.00578034682080925 0.224926689755874 0.989167506074023 0.9999976389434 GO:0015276 ligand-gated monoatomic ion channel activity 1/479 186/18639 0.00537634408602151 0.209206007138528 0.992303445935769 0.9999976389434 GO:0140097 catalytic activity, acting on DNA 3/479 336/18639 0.00892857142857143 0.347431404712198 0.992588298049044 0.9999976389434 GO:0022834 ligand-gated channel activity 1/479 188/18639 0.00531914893617021 0.206980411317905 0.992697842291544 0.9999976389434 GO:0019787 ubiquitin-like protein transferase activity 5/479 479/18639 0.0104384133611691 0.406182853108206 0.994764082006542 0.9999976389434 GO:0061630 ubiquitin protein ligase activity 3/479 353/18639 0.0084985835694051 0.330699580689231 0.994834169215507 0.9999976389434 GO:0031267 small GTPase binding 2/479 283/18639 0.00706713780918728 0.27499870903015 0.99488302248542 0.9999976389434 GO:0141003 histone H2AX kinase activity 3/479 354/18639 0.00847457627118644 0.329765401082764 0.994943371131759 0.9999976389434 GO:0008168 methyltransferase activity 1/479 204/18639 0.00490196078431373 0.190746653567481 0.995207083071164 0.9999976389434 GO:0140996 histone H3 kinase activity 3/479 357/18639 0.00840336134453781 0.326994263258539 0.995257721520167 0.9999976389434 GO:0035173 histone kinase activity 3/479 360/18639 0.00833333333333333 0.324269311064718 0.995553088519925 0.9999976389434 GO:0106310 protein serine kinase activity 3/479 361/18639 0.00831024930747922 0.323371058125481 0.995647518193817 0.9999976389434 GO:0030695 GTPase regulator activity 5/479 489/18639 0.0102249488752556 0.397876455294133 0.995668739524979 0.9999976389434 GO:0060589 nucleoside-triphosphatase regulator activity 5/479 490/18639 0.0102040816326531 0.397064462528226 0.99575047981804 0.9999976389434 GO:0004674 protein serine/threonine kinase activity 4/479 433/18639 0.0092378752886836 0.359467134667586 0.996175651064993 0.9999976389434 GO:0016741 transferase activity, transferring one-carbon groups 1/479 215/18639 0.00465116279069767 0.180987522454726 0.99641246351316 0.9999976389434 GO:0061659 ubiquitin-like protein ligase activity 3/479 372/18639 0.00806451612903226 0.313809010707792 0.996565901200627 0.9999976389434 GO:0004842 ubiquitin-protein transferase activity 4/479 449/18639 0.0089086859688196 0.346657615392126 0.997236867761023 0.9999976389434 GO:0140098 catalytic activity, acting on RNA 3/479 387/18639 0.00775193798449612 0.301645870757877 0.997520526509324 0.9999976389434 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 1/479 243/18639 0.00411522633744856 0.160132993118379 0.998285153296349 0.9999976389434 GO:0004676 3-phosphoinositide-dependent protein kinase activity 1/479 245/18639 0.00408163265306122 0.158825785011291 0.998373296289274 0.9999976389434 GO:0004711 ribosomal protein S6 kinase activity 1/479 245/18639 0.00408163265306122 0.158825785011291 0.998373296289274 0.9999976389434 GO:0035175 histone H3S10 kinase activity 1/479 245/18639 0.00408163265306122 0.158825785011291 0.998373296289274 0.9999976389434 GO:0035979 histone H2AXS139 kinase activity 1/479 245/18639 0.00408163265306122 0.158825785011291 0.998373296289274 0.9999976389434 GO:0044022 histone H3S28 kinase activity 1/479 245/18639 0.00408163265306122 0.158825785011291 0.998373296289274 0.9999976389434 GO:0044023 histone H4S1 kinase activity 1/479 245/18639 0.00408163265306122 0.158825785011291 0.998373296289274 0.9999976389434 GO:0044024 histone H2AS1 kinase activity 1/479 245/18639 0.00408163265306122 0.158825785011291 0.998373296289274 0.9999976389434 GO:0044025 histone H2BS14 kinase activity 1/479 245/18639 0.00408163265306122 0.158825785011291 0.998373296289274 0.9999976389434 GO:0072354 histone H3T3 kinase activity 1/479 245/18639 0.00408163265306122 0.158825785011291 0.998373296289274 0.9999976389434 GO:0072371 histone H2AS121 kinase activity 1/479 245/18639 0.00408163265306122 0.158825785011291 0.998373296289274 0.9999976389434 GO:0072518 Rho-dependent protein serine/threonine kinase activity 1/479 245/18639 0.00408163265306122 0.158825785011291 0.998373296289274 0.9999976389434 GO:0140823 histone H2BS36 kinase activity 1/479 245/18639 0.00408163265306122 0.158825785011291 0.998373296289274 0.9999976389434 GO:0140855 histone H3S57 kinase activity 1/479 245/18639 0.00408163265306122 0.158825785011291 0.998373296289274 0.9999976389434 GO:0140995 histone H2A kinase activity 1/479 245/18639 0.00408163265306122 0.158825785011291 0.998373296289274 0.9999976389434 GO:0140997 histone H4 kinase activity 1/479 245/18639 0.00408163265306122 0.158825785011291 0.998373296289274 0.9999976389434 GO:0140998 histone H2B kinase activity 1/479 245/18639 0.00408163265306122 0.158825785011291 0.998373296289274 0.9999976389434 GO:1990244 histone H2AT120 kinase activity 1/479 245/18639 0.00408163265306122 0.158825785011291 0.998373296289274 0.9999976389434 GO:0004677 DNA-dependent protein kinase activity 1/479 246/18639 0.0040650406504065 0.158180151738887 0.998415657443859 0.9999976389434 GO:0140857 histone H3T45 kinase activity 1/479 246/18639 0.0040650406504065 0.158180151738887 0.998415657443859 0.9999976389434 GO:0035403 histone H3T6 kinase activity 1/479 247/18639 0.00404858299595142 0.15753974626626 0.998456917710503 0.9999976389434 GO:0004679 AMP-activated protein kinase activity 1/479 248/18639 0.00403225806451613 0.156904505353896 0.998497105640944 0.9999976389434 GO:0022836 gated channel activity 1/479 318/18639 0.00314465408805031 0.122365777760271 0.999763891827327 0.9999976389434 GO:0046873 metal ion transmembrane transporter activity 1/479 450/18639 0.00222222222222222 0.0864718162839248 0.999992939467151 0.9999976389434 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 1/479 484/18639 0.00206611570247934 0.0803973498507566 0.999997152879573 0.9999976389434 GO:0001216 DNA-binding transcription activator activity 1/479 491/18639 0.00203665987780041 0.0792511554536989 0.9999976389434 0.9999976389434