ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0009055 electron transfer activity 41/1578 116/18639 0.353448275862069 4.17485577553429 4.99539409760598e-16 5.88956964107746e-13 GO:0022853 active monoatomic ion transmembrane transporter activity 39/1578 118/18639 0.330508474576271 3.90389572726687 3.28104699040958e-14 1.93417720084645e-11 GO:0015078 proton transmembrane transporter activity 47/1578 185/18639 0.254054054054054 3.00083239132669 4.44104727386667e-12 1.3358734363697e-09 GO:0015399 primary active transmembrane transporter activity 44/1578 166/18639 0.265060240963855 3.13083512758257 4.53222539904903e-12 1.3358734363697e-09 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 26/1578 68/18639 0.382352941176471 4.51627152762246 1.42699673404174e-11 3.36485829887041e-09 GO:0008137 NADH dehydrogenase (ubiquinone) activity 18/1578 41/18639 0.439024390243902 5.18566261708244 1.38396160887465e-09 2.51410719840817e-07 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 12/1578 18/18639 0.666666666666667 7.8745247148289 1.49268451135345e-09 2.51410719840817e-07 GO:0003954 NADH dehydrogenase activity 18/1578 44/18639 0.409090909090909 4.83209471137228 5.50810496223655e-09 8.11756968809611e-07 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 19/1578 58/18639 0.327586206896552 3.86937852366592 1.44758498924116e-07 1.89633633590592e-05 GO:0015252 proton channel activity 12/1578 27/18639 0.444444444444444 5.24968314321926 6.78059773964457e-07 7.99432473504095e-05 GO:0051537 2 iron, 2 sulfur cluster binding 11/1578 28/18639 0.392857142857143 4.64034492123846 8.56853794896717e-06 0.000918391476530208 GO:0016651 oxidoreductase activity, acting on NAD(P)H 20/1578 88/18639 0.227272727272727 2.68449706187349 3.60148971375643e-05 0.0035384636437657 GO:0016790 thiolester hydrolase activity 13/1578 44/18639 0.295454545454545 3.48984618043553 4.66861925787218e-05 0.00423407854233177 GO:0031720 haptoglobin binding 6/1578 10/18639 0.6 7.08707224334601 5.68158511143982e-05 0.00442620020809346 GO:0008474 palmitoyl-(protein) hydrolase activity 7/1578 14/18639 0.5 5.90589353612167 6.19372628284235e-05 0.00442620020809346 GO:0098599 palmitoyl hydrolase activity 7/1578 14/18639 0.5 5.90589353612167 6.19372628284235e-05 0.00442620020809346 GO:0003735 structural constituent of ribosome 31/1578 175/18639 0.177142857142857 2.09237370994025 6.38213770463009e-05 0.00442620020809346 GO:0043021 ribonucleoprotein complex binding 31/1578 177/18639 0.175141242937853 2.06873106914996 7.95599980560467e-05 0.0049591655533757 GO:0042625 ATPase-coupled ion transmembrane transporter activity 9/1578 24/18639 0.375 4.42942015209125 8.83311930626715e-05 0.0049591655533757 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 9/1578 24/18639 0.375 4.42942015209125 8.83311930626715e-05 0.0049591655533757 GO:0046961 proton-transporting ATPase activity, rotational mechanism 9/1578 24/18639 0.375 4.42942015209125 8.83311930626715e-05 0.0049591655533757 GO:0017070 U6 snRNA binding 7/1578 16/18639 0.4375 5.16765684410646 0.000177387413146484 0.00950464203516384 GO:0051082 unfolded protein binding 23/1578 121/18639 0.190082644628099 2.24521572447601 0.000185417105011678 0.00950464203516384 GO:0045296 cadherin binding 48/1578 334/18639 0.143712574850299 1.69750233373557 0.000204424463806311 0.010042351784485 GO:0140104 molecular carrier activity 38/1578 249/18639 0.152610441767068 1.8026020431536 0.000273351344718155 0.0128912494169082 GO:0140297 DNA-binding transcription factor binding 64/1578 488/18639 0.131147540983607 1.54908682914667 0.000292445874342205 0.0132612956095946 GO:0070628 proteasome binding 7/1578 18/18639 0.388888888888889 4.59347275031686 0.000424162256264378 0.0185217518568778 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 13/1578 54/18639 0.240740740740741 2.84357836924377 0.000448594695308512 0.018889040920312 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 48/1578 349/18639 0.137535816618911 1.62454378070969 0.00056452128310039 0.0229507100957021 GO:0005344 oxygen carrier activity 6/1578 14/18639 0.428571428571429 5.06219445953286 0.00060342868120296 0.0237147471712763 GO:0016504 peptidase activator activity 13/1578 57/18639 0.228070175438596 2.69391634980989 0.000780797431519813 0.0296954894116729 GO:0043539 protein serine/threonine kinase activator activity 15/1578 73/18639 0.205479452054795 2.42707953539247 0.00102041303762961 0.0370677971934732 GO:0002020 protease binding 23/1578 136/18639 0.169117647058824 1.99758163721762 0.00103752104103869 0.0370677971934732 GO:0032182 ubiquitin-like protein binding 21/1578 120/18639 0.175 2.06706273764259 0.00107529718877593 0.0372875113402006 GO:0140296 general transcription initiation factor binding 12/1578 53/18639 0.226415094339623 2.67436688428151 0.00131563822925976 0.0441253381023366 GO:0042626 ATPase-coupled transmembrane transporter activity 18/1578 98/18639 0.183673469387755 2.16951191122837 0.00134733856801028 0.0441253381023366 GO:0001540 amyloid-beta binding 16/1578 83/18639 0.192771084337349 2.27697100187824 0.00144317296517178 0.0447763401562507 GO:0008135 translation factor activity, RNA binding 16/1578 83/18639 0.192771084337349 2.27697100187824 0.00144317296517178 0.0447763401562507 GO:0017069 snRNA binding 12/1578 54/18639 0.222222222222222 2.62484157160963 0.00156336495324582 0.0472617251250467 GO:0180051 translation factor activity 16/1578 84/18639 0.19047619047619 2.24986420423683 0.00164538754366193 0.0484977978494354 GO:0043130 ubiquitin binding 18/1578 100/18639 0.18 2.1261216730038 0.00170899807059687 0.0491441152496027 GO:0003713 transcription coactivator activity 36/1578 256/18639 0.140625 1.66103255703422 0.00176866211256526 0.0496488721598677 GO:0022804 active transmembrane transporter activity 57/1578 457/18639 0.12472647702407 1.47324258887937 0.00200228345112442 0.0548998183459462 GO:0005049 nuclear export signal receptor activity 5/1578 12/18639 0.416666666666667 4.92157794676806 0.00206239479036957 0.05526280586013 GO:0060590 ATPase regulator activity 11/1578 49/18639 0.224489795918367 2.65162566927912 0.00222135529129766 0.0581995086319988 GO:0004601 peroxidase activity 12/1578 57/18639 0.210526315789474 2.48669201520913 0.00254596226611295 0.0652541198205906 GO:1990381 ubiquitin-specific protease binding 6/1578 18/18639 0.333333333333333 3.93726235741445 0.00277657189171263 0.0696506012835997 GO:0003743 translation initiation factor activity 11/1578 51/18639 0.215686274509804 2.54764034891523 0.00310616745460509 0.074738192428151 GO:0030544 Hsp70 protein binding 11/1578 51/18639 0.215686274509804 2.54764034891523 0.00310616745460509 0.074738192428151 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 12/1578 59/18639 0.203389830508475 2.40239737062577 0.00344413740836281 0.0812127600891951 GO:0017025 TBP-class protein binding 7/1578 25/18639 0.28 3.30730038022814 0.00378612828315098 0.0875263773693139 GO:0051536 iron-sulfur cluster binding 14/1578 76/18639 0.184210526315789 2.17585551330798 0.00429687519472415 0.0974233818188419 GO:0003712 transcription coregulator activity 59/1578 495/18639 0.119191919191919 1.40786957022698 0.00466937083073826 0.103871475649819 GO:0051540 metal cluster binding 14/1578 77/18639 0.181818181818182 2.14759764949879 0.00485217308362051 0.105939112325714 GO:0051287 NAD binding 11/1578 54/18639 0.203703703703704 2.4061047739755 0.00494217055479554 0.105942165165526 GO:0016209 antioxidant activity 15/1578 86/18639 0.174418604651163 2.06019541957733 0.00542281233274784 0.114169566791245 GO:0043022 ribosome binding 18/1578 112/18639 0.160714285714286 1.89832292232482 0.00602326741706193 0.124586531310807 GO:0004129 cytochrome-c oxidase activity 5/1578 15/18639 0.333333333333333 3.93726235741445 0.00630851128527861 0.125879881192185 GO:0140318 protein transporter activity 9/1578 41/18639 0.219512195121951 2.59283130854122 0.0063809053086294 0.125879881192185 GO:0016831 carboxy-lyase activity 8/1578 34/18639 0.235294117647059 2.77924401699843 0.00640610082402978 0.125879881192185 GO:0008239 dipeptidyl-peptidase activity 4/1578 10/18639 0.4 4.72471482889734 0.00708875704752546 0.134800718694073 GO:0070513 death domain binding 4/1578 10/18639 0.4 4.72471482889734 0.00708875704752546 0.134800718694073 GO:0016859 cis-trans isomerase activity 9/1578 42/18639 0.214285714285714 2.53109722976643 0.00752453620029208 0.140816320319752 GO:0140517 protein-RNA adaptor activity 6/1578 22/18639 0.272727272727273 3.22139647424819 0.00832570429171664 0.153375083748968 GO:0016675 oxidoreductase activity, acting on a heme group of donors 5/1578 16/18639 0.3125 3.69118346007605 0.00854515547390584 0.154995973903615 GO:0051087 protein-folding chaperone binding 20/1578 134/18639 0.149253731343284 1.76295329436468 0.00901586989795132 0.161056221358858 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 15/1578 91/18639 0.164835164835165 1.9469978690511 0.00918407573126931 0.161612317718903 GO:0001046 core promoter sequence-specific DNA binding 9/1578 44/18639 0.204545454545455 2.41604735568614 0.0102731783022068 0.172710681222743 GO:0019864 IgG binding 4/1578 11/18639 0.363636363636364 4.29519529899758 0.0104007280464926 0.172710681222743 GO:0032050 clathrin heavy chain binding 4/1578 11/18639 0.363636363636364 4.29519529899758 0.0104007280464926 0.172710681222743 GO:0034713 type I transforming growth factor beta receptor binding 4/1578 11/18639 0.363636363636364 4.29519529899758 0.0104007280464926 0.172710681222743 GO:0035925 mRNA 3'-UTR AU-rich region binding 7/1578 30/18639 0.233333333333333 2.75608365019011 0.0110525152068173 0.180984936511634 GO:0019207 kinase regulator activity 36/1578 287/18639 0.125435540069686 1.48161789059498 0.011240681990045 0.18154471323648 GO:0016922 nuclear receptor binding 20/1578 137/18639 0.145985401459854 1.72434847769976 0.0114179155059415 0.181915167317636 GO:0051018 protein kinase A binding 10/1578 53/18639 0.188679245283019 2.22863907023459 0.0124122391843177 0.195120399977475 GO:0050431 transforming growth factor beta binding 6/1578 24/18639 0.25 2.95294676806084 0.0129842625955441 0.198810981820084 GO:0050699 WW domain binding 6/1578 24/18639 0.25 2.95294676806084 0.0129842625955441 0.198810981820084 GO:0016798 hydrolase activity, acting on glycosyl bonds 19/1578 130/18639 0.146153846153846 1.72633811055864 0.0132844932181274 0.200800224412464 GO:0003925 G protein activity 10/1578 54/18639 0.185185185185185 2.18736797634136 0.0141099820546637 0.210578086613272 GO:0031543 peptidyl-proline dioxygenase activity 4/1578 12/18639 0.333333333333333 3.93726235741445 0.0145698946745541 0.21169414364347 GO:1990247 N6-methyladenosine-containing RNA reader activity 4/1578 12/18639 0.333333333333333 3.93726235741445 0.0145698946745541 0.21169414364347 GO:0046332 SMAD binding 13/1578 79/18639 0.164556962025316 1.94371179669827 0.0148755893071723 0.21169414364347 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 8/1578 39/18639 0.205128205128205 2.42293068148581 0.0149029804261306 0.21169414364347 GO:0140142 nucleocytoplasmic carrier activity 7/1578 32/18639 0.21875 2.58382842205323 0.0157608031792034 0.221214130336676 GO:0019887 protein kinase regulator activity 32/1578 255/18639 0.125490196078431 1.4822634757325 0.0160234365615733 0.22225449065994 GO:0016853 isomerase activity 24/1578 180/18639 0.133333333333333 1.57490494296578 0.0175095214570736 0.240043323231276 GO:0003756 protein disulfide isomerase activity 5/1578 19/18639 0.263157894736842 3.10836501901141 0.018391976750871 0.246410688514511 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 5/1578 19/18639 0.263157894736842 3.10836501901141 0.018391976750871 0.246410688514511 GO:0017154 semaphorin receptor activity 4/1578 13/18639 0.307692307692308 3.63439602222872 0.0196590518842198 0.25753357968328 GO:0070700 BMP receptor binding 4/1578 13/18639 0.307692307692308 3.63439602222872 0.0196590518842198 0.25753357968328 GO:0019838 growth factor binding 19/1578 136/18639 0.139705882352941 1.65017613509282 0.0206730064208011 0.265917248971698 GO:0140713 histone chaperone activity 22/1578 164/18639 0.134146341463415 1.5845080218863 0.0208552905108274 0.265917248971698 GO:0031491 nucleosome binding 12/1578 74/18639 0.162162162162162 1.91542493063406 0.020975660860363 0.265917248971698 GO:0015035 protein-disulfide reductase activity 7/1578 34/18639 0.205882352941176 2.43183851487363 0.0217383168099197 0.272653994881865 GO:0031492 nucleosomal DNA binding 8/1578 42/18639 0.19047619047619 2.24986420423683 0.0228467049259524 0.279328593974848 GO:0016004 phospholipase activator activity 5/1578 20/18639 0.25 2.95294676806084 0.0228540230004797 0.279328593974848 GO:0001671 ATPase activator activity 6/1578 27/18639 0.222222222222222 2.62484157160963 0.022981232922443 0.279328593974848 GO:0030295 protein kinase activator activity 19/1578 139/18639 0.136690647482014 1.61456082282463 0.0253888027450529 0.303190175115899 GO:0019763 immunoglobulin receptor activity 4/1578 14/18639 0.285714285714286 3.37479630635524 0.0257158757519846 0.303190175115899 GO:0034236 protein kinase A catalytic subunit binding 4/1578 14/18639 0.285714285714286 3.37479630635524 0.0257158757519846 0.303190175115899 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 6/1578 28/18639 0.214285714285714 2.53109722976643 0.0272151138802782 0.316185128368704 GO:0140597 protein carrier chaperone 24/1578 188/18639 0.127659574468085 1.50788771135021 0.0280213432256429 0.316185128368704 GO:0001098 basal transcription machinery binding 10/1578 60/18639 0.166666666666667 1.96863117870722 0.0281298602759523 0.316185128368704 GO:0001099 basal RNA polymerase II transcription machinery binding 10/1578 60/18639 0.166666666666667 1.96863117870722 0.0281298602759523 0.316185128368704 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 17/1578 122/18639 0.139344262295082 1.64590475596834 0.0281589808979762 0.316185128368704 GO:0042393 histone binding 30/1578 247/18639 0.121457489878543 1.4346300087745 0.0286164725351886 0.318290765273465 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 18/1578 132/18639 0.136363636363636 1.61069823712409 0.0296186410063605 0.326358670528028 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 10/1578 61/18639 0.163934426229508 1.93635853643334 0.0311853062386977 0.338942841668639 GO:0042277 peptide binding 30/1578 249/18639 0.120481927710843 1.4231068761739 0.0314656815697123 0.338942841668639 GO:0097110 scaffold protein binding 11/1578 70/18639 0.157142857142857 1.85613796849538 0.0325157116833396 0.338942841668639 GO:0016251 RNA polymerase II general transcription initiation factor activity 9/1578 53/18639 0.169811320754717 2.00577516321113 0.0325232965382055 0.338942841668639 GO:0016860 intramolecular oxidoreductase activity 9/1578 53/18639 0.169811320754717 2.00577516321113 0.0325232965382055 0.338942841668639 GO:0015929 hexosaminidase activity 4/1578 15/18639 0.266666666666667 3.14980988593156 0.0327730991944231 0.338942841668639 GO:0042809 nuclear vitamin D receptor binding 4/1578 15/18639 0.266666666666667 3.14980988593156 0.0327730991944231 0.338942841668639 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 5/1578 22/18639 0.227272727272727 2.68449706187349 0.0337352699885031 0.34211097052693 GO:0061133 endopeptidase activator activity 5/1578 22/18639 0.227272727272727 2.68449706187349 0.0337352699885031 0.34211097052693 GO:0061775 cohesin loader activity 20/1578 153/18639 0.130718954248366 1.54402445388802 0.033949943640077 0.34211097052693 GO:0005518 collagen binding 11/1578 72/18639 0.152777777777778 1.80457858048162 0.0389822502015981 0.389492143963425 GO:0019210 kinase inhibitor activity 13/1578 90/18639 0.144444444444444 1.70614702154626 0.0394074968409722 0.390432258617699 GO:0097027 ubiquitin-protein transferase activator activity 4/1578 16/18639 0.25 2.95294676806084 0.0408490804345956 0.401342215269901 GO:0031490 chromatin DNA binding 17/1578 128/18639 0.1328125 1.56875297053232 0.0420344845435254 0.40957567997369 GO:0019209 kinase activator activity 19/1578 148/18639 0.128378378378378 1.51637807008529 0.0444401238706451 0.416362857654921 GO:0033218 amide binding 29/1578 247/18639 0.117408906882591 1.38680900848201 0.0452233880810987 0.416362857654921 GO:0038024 cargo receptor activity 10/1578 65/18639 0.153846153846154 1.81719801111436 0.0457370195647699 0.416362857654921 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 3/1578 10/18639 0.3 3.543536121673 0.0462625397394357 0.416362857654921 GO:0008140 cAMP response element binding protein binding 3/1578 10/18639 0.3 3.543536121673 0.0462625397394357 0.416362857654921 GO:0008641 ubiquitin-like modifier activating enzyme activity 3/1578 10/18639 0.3 3.543536121673 0.0462625397394357 0.416362857654921 GO:0015203 polyamine transmembrane transporter activity 3/1578 10/18639 0.3 3.543536121673 0.0462625397394357 0.416362857654921 GO:0030957 Tat protein binding 3/1578 10/18639 0.3 3.543536121673 0.0462625397394357 0.416362857654921 GO:0031434 mitogen-activated protein kinase kinase binding 3/1578 10/18639 0.3 3.543536121673 0.0462625397394357 0.416362857654921 GO:1990757 ubiquitin ligase activator activity 3/1578 10/18639 0.3 3.543536121673 0.0462625397394357 0.416362857654921 GO:0001091 RNA polymerase II general transcription initiation factor binding 5/1578 24/18639 0.208333333333333 2.46078897338403 0.0473583925300034 0.416683170096074 GO:0060229 lipase activator activity 5/1578 24/18639 0.208333333333333 2.46078897338403 0.0473583925300034 0.416683170096074 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 5/1578 24/18639 0.208333333333333 2.46078897338403 0.0473583925300034 0.416683170096074 GO:0004177 aminopeptidase activity 7/1578 40/18639 0.175 2.06706273764259 0.0485796103076736 0.421142357005494 GO:0015036 disulfide oxidoreductase activity 7/1578 40/18639 0.175 2.06706273764259 0.0485796103076736 0.421142357005494 GO:0051787 misfolded protein binding 4/1578 17/18639 0.235294117647059 2.77924401699843 0.0499486573292511 0.424287834040006 GO:0004860 protein kinase inhibitor activity 12/1578 84/18639 0.142857142857143 1.68739815317762 0.0500220601624774 0.424287834040006 GO:0051117 ATPase binding 12/1578 84/18639 0.142857142857143 1.68739815317762 0.0500220601624774 0.424287834040006 GO:0000510 H3-H4 histone complex chaperone activity 19/1578 151/18639 0.125827814569536 1.48625135346108 0.0526336860276379 0.433951858927168 GO:0140584 chromatin extrusion motor activity 19/1578 151/18639 0.125827814569536 1.48625135346108 0.0526336860276379 0.433951858927168 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 19/1578 151/18639 0.125827814569536 1.48625135346108 0.0526336860276379 0.433951858927168 GO:0140849 ATP-dependent H2AZ histone chaperone activity 19/1578 151/18639 0.125827814569536 1.48625135346108 0.0526336860276379 0.433951858927168 GO:0031625 ubiquitin protein ligase binding 34/1578 302/18639 0.112582781456954 1.32980384257044 0.0534821188077997 0.43788484773886 GO:0017056 structural constituent of nuclear pore 5/1578 25/18639 0.2 2.36235741444867 0.0552257565152714 0.439993361547106 GO:0047617 fatty acyl-CoA hydrolase activity 5/1578 25/18639 0.2 2.36235741444867 0.0552257565152714 0.439993361547106 GO:0015616 DNA translocase activity 19/1578 152/18639 0.125 1.47647338403042 0.055587467512701 0.439993361547106 GO:0140674 ATP-dependent histone chaperone activity 19/1578 152/18639 0.125 1.47647338403042 0.055587467512701 0.439993361547106 GO:0071889 14-3-3 protein binding 6/1578 33/18639 0.181818181818182 2.14759764949879 0.0559432032364564 0.439993361547106 GO:0036002 pre-mRNA binding 9/1578 59/18639 0.152542372881356 1.80179802796932 0.0588832452093944 0.439993361547106 GO:0140223 general transcription initiation factor activity 10/1578 68/18639 0.147058823529412 1.73702751062402 0.0592617542504175 0.439993361547106 GO:1990841 promoter-specific chromatin binding 10/1578 68/18639 0.147058823529412 1.73702751062402 0.0592617542504175 0.439993361547106 GO:0005114 type II transforming growth factor beta receptor binding 3/1578 11/18639 0.272727272727273 3.22139647424819 0.0597107191242892 0.439993361547106 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 3/1578 11/18639 0.272727272727273 3.22139647424819 0.0597107191242892 0.439993361547106 GO:0015173 aromatic amino acid transmembrane transporter activity 3/1578 11/18639 0.272727272727273 3.22139647424819 0.0597107191242892 0.439993361547106 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 3/1578 11/18639 0.272727272727273 3.22139647424819 0.0597107191242892 0.439993361547106 GO:0019107 myristoyltransferase activity 3/1578 11/18639 0.272727272727273 3.22139647424819 0.0597107191242892 0.439993361547106 GO:0048185 activin binding 3/1578 11/18639 0.272727272727273 3.22139647424819 0.0597107191242892 0.439993361547106 GO:0048407 platelet-derived growth factor binding 3/1578 11/18639 0.272727272727273 3.22139647424819 0.0597107191242892 0.439993361547106 GO:0050786 RAGE receptor binding 3/1578 11/18639 0.272727272727273 3.22139647424819 0.0597107191242892 0.439993361547106 GO:0001221 transcription coregulator binding 15/1578 115/18639 0.130434782608696 1.54066787898826 0.0611620682094045 0.445091250969353 GO:0003714 transcription corepressor activity 24/1578 204/18639 0.117647058823529 1.38962200849922 0.0625694946060253 0.445091250969353 GO:0019825 oxygen binding 6/1578 34/18639 0.176470588235294 2.08443301274883 0.0632728217564285 0.445091250969353 GO:0052866 phosphatidylinositol phosphate phosphatase activity 6/1578 34/18639 0.176470588235294 2.08443301274883 0.0632728217564285 0.445091250969353 GO:0016830 carbon-carbon lyase activity 8/1578 51/18639 0.156862745098039 1.85282934466562 0.0633187981470164 0.445091250969353 GO:0005160 transforming growth factor beta receptor binding 5/1578 26/18639 0.192307692307692 2.27149751389295 0.0638001877979819 0.445091250969353 GO:0016289 acyl-CoA hydrolase activity 5/1578 26/18639 0.192307692307692 2.27149751389295 0.0638001877979819 0.445091250969353 GO:0050750 low-density lipoprotein particle receptor binding 5/1578 26/18639 0.192307692307692 2.27149751389295 0.0638001877979819 0.445091250969353 GO:0070412 R-SMAD binding 5/1578 26/18639 0.192307692307692 2.27149751389295 0.0638001877979819 0.445091250969353 GO:0061659 ubiquitin-like protein ligase activity 40/1578 372/18639 0.10752688172043 1.27008463142402 0.0695925242920013 0.482644624354526 GO:0003924 GTPase activity 36/1578 331/18639 0.108761329305136 1.28466566344641 0.0718862179873925 0.484281768441115 GO:0016874 ligase activity 20/1578 167/18639 0.119760479041916 1.41458527811298 0.0722605007713129 0.484281768441115 GO:0005044 scavenger receptor activity 5/1578 27/18639 0.185185185185185 2.18736797634136 0.0730772229969679 0.484281768441115 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 5/1578 27/18639 0.185185185185185 2.18736797634136 0.0730772229969679 0.484281768441115 GO:0004526 ribonuclease P activity 3/1578 12/18639 0.25 2.95294676806084 0.0747576606075344 0.484281768441115 GO:0070008 serine-type exopeptidase activity 3/1578 12/18639 0.25 2.95294676806084 0.0747576606075344 0.484281768441115 GO:0070679 inositol 1,4,5 trisphosphate binding 3/1578 12/18639 0.25 2.95294676806084 0.0747576606075344 0.484281768441115 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 3/1578 12/18639 0.25 2.95294676806084 0.0747576606075344 0.484281768441115 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 3/1578 12/18639 0.25 2.95294676806084 0.0747576606075344 0.484281768441115 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 3/1578 12/18639 0.25 2.95294676806084 0.0747576606075344 0.484281768441115 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 3/1578 12/18639 0.25 2.95294676806084 0.0747576606075344 0.484281768441115 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 3/1578 12/18639 0.25 2.95294676806084 0.0747576606075344 0.484281768441115 GO:0044389 ubiquitin-like protein ligase binding 35/1578 322/18639 0.108695652173913 1.28388989915689 0.0755458374199787 0.485448452961991 GO:0140658 ATP-dependent chromatin remodeler activity 19/1578 158/18639 0.120253164556962 1.42040477451028 0.0757612513528468 0.485448452961991 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 6/1578 36/18639 0.166666666666667 1.96863117870722 0.0795429995242983 0.501503724273517 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 6/1578 36/18639 0.166666666666667 1.96863117870722 0.0795429995242983 0.501503724273517 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 6/1578 36/18639 0.166666666666667 1.96863117870722 0.0795429995242983 0.501503724273517 GO:0008094 ATP-dependent activity, acting on DNA 24/1578 210/18639 0.114285714285714 1.3499185225421 0.081108866968876 0.501981256156093 GO:0005507 copper ion binding 9/1578 63/18639 0.142857142857143 1.68739815317762 0.0824352173235238 0.501981256156093 GO:0019789 SUMO transferase activity 5/1578 28/18639 0.178571428571429 2.10924769147203 0.0830472467179873 0.501981256156093 GO:0046966 nuclear thyroid hormone receptor binding 5/1578 28/18639 0.178571428571429 2.10924769147203 0.0830472467179873 0.501981256156093 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 8/1578 54/18639 0.148148148148148 1.74989438107309 0.0830609353407715 0.501981256156093 GO:0031418 L-ascorbic acid binding 4/1578 20/18639 0.2 2.36235741444867 0.0832574858108593 0.501981256156093 GO:0043024 ribosomal small subunit binding 4/1578 20/18639 0.2 2.36235741444867 0.0832574858108593 0.501981256156093 GO:0052745 inositol phosphate phosphatase activity 4/1578 20/18639 0.2 2.36235741444867 0.0832574858108593 0.501981256156093 GO:0003689 DNA clamp loader activity 19/1578 160/18639 0.11875 1.4026497148289 0.0834506583601307 0.501981256156093 GO:0140097 catalytic activity, acting on DNA 36/1578 336/18639 0.107142857142857 1.26554861488322 0.0847654488856271 0.507301848914489 GO:0003697 single-stranded DNA binding 15/1578 121/18639 0.12396694214876 1.46427112465827 0.0866132399010781 0.51574247395642 GO:0031072 heat shock protein binding 16/1578 131/18639 0.122137404580153 1.4426610164572 0.0872581838476587 0.516971853047184 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 3/1578 13/18639 0.230769230769231 2.72579701667154 0.0912872432245287 0.521742650161214 GO:0005338 nucleotide-sugar transmembrane transporter activity 3/1578 13/18639 0.230769230769231 2.72579701667154 0.0912872432245287 0.521742650161214 GO:0035325 Toll-like receptor binding 3/1578 13/18639 0.230769230769231 2.72579701667154 0.0912872432245287 0.521742650161214 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 3/1578 13/18639 0.230769230769231 2.72579701667154 0.0912872432245287 0.521742650161214 GO:0089720 caspase binding 3/1578 13/18639 0.230769230769231 2.72579701667154 0.0912872432245287 0.521742650161214 GO:0140666 annealing activity 3/1578 13/18639 0.230769230769231 2.72579701667154 0.0912872432245287 0.521742650161214 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 3/1578 13/18639 0.230769230769231 2.72579701667154 0.0912872432245287 0.521742650161214 GO:0046906 tetrapyrrole binding 18/1578 152/18639 0.118421052631579 1.39876425855513 0.0919453185117003 0.521742650161214 GO:0020037 heme binding 17/1578 142/18639 0.119718309859155 1.41408718470519 0.0920462012158885 0.521742650161214 GO:0005123 death receptor binding 4/1578 21/18639 0.19047619047619 2.24986420423683 0.0962685721913488 0.53791775646256 GO:0010314 phosphatidylinositol-5-phosphate binding 4/1578 21/18639 0.19047619047619 2.24986420423683 0.0962685721913488 0.53791775646256 GO:0140312 cargo adaptor activity 4/1578 21/18639 0.19047619047619 2.24986420423683 0.0962685721913488 0.53791775646256 GO:0005109 frizzled binding 6/1578 38/18639 0.157894736842105 1.86501901140684 0.0979332177544045 0.542081050387056 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 6/1578 38/18639 0.157894736842105 1.86501901140684 0.0979332177544045 0.542081050387056 GO:0019955 cytokine binding 17/1578 144/18639 0.118055555555556 1.39444708491762 0.101403713834427 0.556891879056324 GO:0061134 peptidase regulator activity 25/1578 226/18639 0.110619469026549 1.30661361418621 0.101553650548863 0.556891879056324 GO:0033612 receptor serine/threonine kinase binding 5/1578 30/18639 0.166666666666667 1.96863117870722 0.105004113207522 0.573147451257723 GO:0030246 carbohydrate binding 30/1578 280/18639 0.107142857142857 1.26554861488322 0.107504879952481 0.577183116236976 GO:0032266 phosphatidylinositol-3-phosphate binding 7/1578 48/18639 0.145833333333333 1.72255228136882 0.107796118449898 0.577183116236976 GO:0008494 translation activator activity 3/1578 14/18639 0.214285714285714 2.53109722976643 0.109170343444314 0.577183116236976 GO:0015926 glucosidase activity 3/1578 14/18639 0.214285714285714 2.53109722976643 0.109170343444314 0.577183116236976 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 3/1578 14/18639 0.214285714285714 2.53109722976643 0.109170343444314 0.577183116236976 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 3/1578 14/18639 0.214285714285714 2.53109722976643 0.109170343444314 0.577183116236976 GO:0061665 SUMO ligase activity 3/1578 14/18639 0.214285714285714 2.53109722976643 0.109170343444314 0.577183116236976 GO:0140375 immune receptor activity 18/1578 156/18639 0.115384615384615 1.36289850833577 0.110501055662579 0.581610467081161 GO:0004896 cytokine receptor activity 12/1578 96/18639 0.125 1.47647338403042 0.11109132821344 0.582118559838428 GO:0008013 beta-catenin binding 13/1578 106/18639 0.122641509433962 1.44861539565249 0.111992687141084 0.584245036014771 GO:0005525 GTP binding 39/1578 378/18639 0.103174603174603 1.21867644396161 0.114434783927662 0.594355111236625 GO:0070325 lipoprotein particle receptor binding 5/1578 31/18639 0.161290322580645 1.90512694713602 0.116949194997474 0.600486479423266 GO:0016763 pentosyltransferase activity 7/1578 49/18639 0.142857142857143 1.68739815317762 0.117103554999681 0.600486479423266 GO:0004518 nuclease activity 23/1578 209/18639 0.110047846889952 1.29986173522295 0.117143248742452 0.600486479423266 GO:0004532 RNA exonuclease activity 6/1578 40/18639 0.15 1.7717680608365 0.11837106190924 0.600871061653656 GO:0030331 nuclear estrogen receptor binding 6/1578 40/18639 0.15 1.7717680608365 0.11837106190924 0.600871061653656 GO:0051020 GTPase binding 33/1578 315/18639 0.104761904761905 1.23742531233026 0.118747207264887 0.600871061653656 GO:0004197 cysteine-type endopeptidase activity 11/1578 88/18639 0.125 1.47647338403042 0.123365970782725 0.620907288850955 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 15/1578 128/18639 0.1171875 1.38419379752852 0.123760146632718 0.620907288850955 GO:0008171 O-methyltransferase activity 4/1578 23/18639 0.173913043478261 2.05422383865102 0.124894913382271 0.621312670370033 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 4/1578 23/18639 0.173913043478261 2.05422383865102 0.124894913382271 0.621312670370033 GO:0000774 adenyl-nucleotide exchange factor activity 3/1578 15/18639 0.2 2.36235741444867 0.128269654506786 0.62491703579959 GO:0004559 alpha-mannosidase activity 3/1578 15/18639 0.2 2.36235741444867 0.128269654506786 0.62491703579959 GO:0031005 filamin binding 3/1578 15/18639 0.2 2.36235741444867 0.128269654506786 0.62491703579959 GO:0050700 CARD domain binding 3/1578 15/18639 0.2 2.36235741444867 0.128269654506786 0.62491703579959 GO:0120283 protein serine/threonine kinase binding 3/1578 15/18639 0.2 2.36235741444867 0.128269654506786 0.62491703579959 GO:0022884 macromolecule transmembrane transporter activity 5/1578 32/18639 0.15625 1.84559173003802 0.129504564486198 0.628336961025629 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 8/1578 60/18639 0.133333333333333 1.57490494296578 0.132155309816645 0.635963715403367 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 8/1578 60/18639 0.133333333333333 1.57490494296578 0.132155309816645 0.635963715403367 GO:0016887 ATP hydrolysis activity 42/1578 417/18639 0.100719424460432 1.18967639576552 0.135975496236783 0.650897449421812 GO:0005178 integrin binding 18/1578 161/18639 0.111801242236025 1.32057246770422 0.136690535297375 0.650897449421812 GO:0005048 signal sequence binding 7/1578 51/18639 0.137254901960784 1.62122567658242 0.136914815484826 0.650897449421812 GO:0061630 ubiquitin protein ligase activity 36/1578 353/18639 0.101983002832861 1.20460151444975 0.139919181177713 0.659498862528537 GO:0004622 lysophospholipase activity 4/1578 24/18639 0.166666666666667 1.96863117870722 0.140402217552725 0.659498862528537 GO:0070300 phosphatidic acid binding 4/1578 24/18639 0.166666666666667 1.96863117870722 0.140402217552725 0.659498862528537 GO:0140311 protein sequestering activity 5/1578 33/18639 0.151515151515152 1.78966470791566 0.142640521852224 0.662935770722275 GO:0004540 RNA nuclease activity 14/1578 121/18639 0.115702479338843 1.36665304968105 0.143588817342346 0.662935770722275 GO:0016755 aminoacyltransferase activity 49/1578 496/18639 0.0987903225806452 1.16689025512081 0.144108361631694 0.662935770722275 GO:0001618 virus receptor activity 10/1578 81/18639 0.123456790123457 1.45824531756091 0.145511649051954 0.662935770722275 GO:0030971 receptor tyrosine kinase binding 10/1578 81/18639 0.123456790123457 1.45824531756091 0.145511649051954 0.662935770722275 GO:0030159 signaling receptor complex adaptor activity 7/1578 52/18639 0.134615384615385 1.59004825972507 0.147395512696004 0.662935770722275 GO:0000062 fatty-acyl-CoA binding 3/1578 16/18639 0.1875 2.21471007604563 0.14844363313883 0.662935770722275 GO:0005521 lamin binding 3/1578 16/18639 0.1875 2.21471007604563 0.14844363313883 0.662935770722275 GO:0015562 efflux transmembrane transporter activity 3/1578 16/18639 0.1875 2.21471007604563 0.14844363313883 0.662935770722275 GO:0015923 mannosidase activity 3/1578 16/18639 0.1875 2.21471007604563 0.14844363313883 0.662935770722275 GO:0031435 mitogen-activated protein kinase kinase kinase binding 3/1578 16/18639 0.1875 2.21471007604563 0.14844363313883 0.662935770722275 GO:0043023 ribosomal large subunit binding 3/1578 16/18639 0.1875 2.21471007604563 0.14844363313883 0.662935770722275 GO:0070411 I-SMAD binding 3/1578 16/18639 0.1875 2.21471007604563 0.14844363313883 0.662935770722275 GO:0008375 acetylglucosaminyltransferase activity 6/1578 43/18639 0.13953488372093 1.64815633566186 0.152611312719145 0.673950416169718 GO:0048156 tau protein binding 6/1578 43/18639 0.13953488372093 1.64815633566186 0.152611312719145 0.673950416169718 GO:0140272 exogenous protein binding 10/1578 82/18639 0.121951219512195 1.44046183807846 0.153966797677216 0.673950416169718 GO:0003707 nuclear steroid receptor activity 4/1578 25/18639 0.16 1.88988593155894 0.156626305369383 0.673950416169718 GO:0004709 MAP kinase kinase kinase activity 4/1578 25/18639 0.16 1.88988593155894 0.156626305369383 0.673950416169718 GO:0008139 nuclear localization sequence binding 4/1578 25/18639 0.16 1.88988593155894 0.156626305369383 0.673950416169718 GO:0015662 P-type ion transporter activity 4/1578 25/18639 0.16 1.88988593155894 0.156626305369383 0.673950416169718 GO:0042974 nuclear retinoic acid receptor binding 4/1578 25/18639 0.16 1.88988593155894 0.156626305369383 0.673950416169718 GO:0120020 cholesterol transfer activity 4/1578 25/18639 0.16 1.88988593155894 0.156626305369383 0.673950416169718 GO:0140358 P-type transmembrane transporter activity 4/1578 25/18639 0.16 1.88988593155894 0.156626305369383 0.673950416169718 GO:0030695 GTPase regulator activity 48/1578 489/18639 0.098159509202454 1.1594392218153 0.157492007622772 0.67521118904454 GO:0046982 protein heterodimerization activity 37/1578 369/18639 0.100271002710027 1.18437973353118 0.159925505142806 0.683071364871465 GO:0060589 nucleoside-triphosphatase regulator activity 48/1578 490/18639 0.0979591836734694 1.1570730193218 0.160966678648187 0.683071364871465 GO:0019787 ubiquitin-like protein transferase activity 47/1578 479/18639 0.0981210855949896 1.15898537034538 0.161063477043484 0.683071364871465 GO:0031267 small GTPase binding 29/1578 283/18639 0.102473498233216 1.21039514167865 0.163663870698366 0.691611840693095 GO:0000287 magnesium ion binding 24/1578 230/18639 0.104347826086957 1.23253430319061 0.167569967938566 0.693260246268646 GO:0140463 chromatin-protein adaptor activity 7/1578 54/18639 0.12962962962963 1.53115758343895 0.169439029254464 0.693260246268646 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 3/1578 17/18639 0.176470588235294 2.08443301274883 0.16954969938374 0.693260246268646 GO:0004549 tRNA-specific ribonuclease activity 3/1578 17/18639 0.176470588235294 2.08443301274883 0.16954969938374 0.693260246268646 GO:0030169 low-density lipoprotein particle binding 3/1578 17/18639 0.176470588235294 2.08443301274883 0.16954969938374 0.693260246268646 GO:0070403 NAD+ binding 3/1578 17/18639 0.176470588235294 2.08443301274883 0.16954969938374 0.693260246268646 GO:1901567 fatty acid derivative binding 3/1578 17/18639 0.176470588235294 2.08443301274883 0.16954969938374 0.693260246268646 GO:1990226 histone methyltransferase binding 3/1578 17/18639 0.176470588235294 2.08443301274883 0.16954969938374 0.693260246268646 GO:0000175 3'-5'-RNA exonuclease activity 5/1578 35/18639 0.142857142857143 1.68739815317762 0.170522028344281 0.693260246268646 GO:0005154 epidermal growth factor receptor binding 5/1578 35/18639 0.142857142857143 1.68739815317762 0.170522028344281 0.693260246268646 GO:0140566 histone reader activity 5/1578 35/18639 0.142857142857143 1.68739815317762 0.170522028344281 0.693260246268646 GO:0004527 exonuclease activity 10/1578 84/18639 0.119047619047619 1.40616512764802 0.17159031155542 0.693426976754666 GO:0019865 immunoglobulin binding 4/1578 26/18639 0.153846153846154 1.81719801111436 0.173503781291456 0.693426976754666 GO:0030247 polysaccharide binding 4/1578 26/18639 0.153846153846154 1.81719801111436 0.173503781291456 0.693426976754666 GO:0050681 nuclear androgen receptor binding 4/1578 26/18639 0.153846153846154 1.81719801111436 0.173503781291456 0.693426976754666 GO:0120014 phospholipid transfer activity 4/1578 26/18639 0.153846153846154 1.81719801111436 0.173503781291456 0.693426976754666 GO:0017124 SH3 domain binding 13/1578 115/18639 0.11304347826087 1.33524549512316 0.174307629925825 0.694286134062662 GO:0003725 double-stranded RNA binding 9/1578 75/18639 0.12 1.4174144486692 0.181895689859179 0.718840051773687 GO:0120013 lipid transfer activity 8/1578 65/18639 0.123076923076923 1.45375840889149 0.182130607747774 0.718840051773687 GO:0055106 ubiquitin-protein transferase regulator activity 5/1578 36/18639 0.138888888888889 1.64052598225602 0.18519606525073 0.718840051773687 GO:1990782 protein tyrosine kinase binding 13/1578 117/18639 0.111111111111111 1.31242078580482 0.190108960900876 0.718840051773687 GO:0050660 flavin adenine dinucleotide binding 10/1578 86/18639 0.116279069767442 1.37346361305155 0.190118801928596 0.718840051773687 GO:0030276 clathrin binding 6/1578 46/18639 0.130434782608696 1.54066787898826 0.190678882108437 0.718840051773687 GO:0030291 protein serine/threonine kinase inhibitor activity 6/1578 46/18639 0.130434782608696 1.54066787898826 0.190678882108437 0.718840051773687 GO:0005385 zinc ion transmembrane transporter activity 4/1578 27/18639 0.148148148148148 1.74989438107309 0.190969269690497 0.718840051773687 GO:0008320 protein transmembrane transporter activity 4/1578 27/18639 0.148148148148148 1.74989438107309 0.190969269690497 0.718840051773687 GO:0000400 four-way junction DNA binding 3/1578 18/18639 0.166666666666667 1.96863117870722 0.191446799200117 0.718840051773687 GO:0000900 mRNA regulatory element binding translation repressor activity 3/1578 18/18639 0.166666666666667 1.96863117870722 0.191446799200117 0.718840051773687 GO:0003746 translation elongation factor activity 3/1578 18/18639 0.166666666666667 1.96863117870722 0.191446799200117 0.718840051773687 GO:0008409 5'-3' exonuclease activity 3/1578 18/18639 0.166666666666667 1.96863117870722 0.191446799200117 0.718840051773687 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 3/1578 18/18639 0.166666666666667 1.96863117870722 0.191446799200117 0.718840051773687 GO:0030228 lipoprotein particle receptor activity 3/1578 18/18639 0.166666666666667 1.96863117870722 0.191446799200117 0.718840051773687 GO:0031690 adrenergic receptor binding 3/1578 18/18639 0.166666666666667 1.96863117870722 0.191446799200117 0.718840051773687 GO:0035615 clathrin adaptor activity 3/1578 18/18639 0.166666666666667 1.96863117870722 0.191446799200117 0.718840051773687 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 3/1578 18/18639 0.166666666666667 1.96863117870722 0.191446799200117 0.718840051773687 GO:0019001 guanyl nucleotide binding 39/1578 400/18639 0.0975 1.15164923954373 0.197925552172102 0.728798930194563 GO:0032561 guanyl ribonucleotide binding 39/1578 400/18639 0.0975 1.15164923954373 0.197925552172102 0.728798930194563 GO:0005504 fatty acid binding 6/1578 47/18639 0.127659574468085 1.50788771135021 0.204109880399572 0.728798930194563 GO:0050840 extracellular matrix binding 8/1578 67/18639 0.119402985074627 1.41036263549174 0.204128181342788 0.728798930194563 GO:0004445 inositol-polyphosphate 5-phosphatase activity 2/1578 10/18639 0.2 2.36235741444867 0.205225822582354 0.728798930194563 GO:0004862 cAMP-dependent protein kinase inhibitor activity 2/1578 10/18639 0.2 2.36235741444867 0.205225822582354 0.728798930194563 GO:0005131 growth hormone receptor binding 2/1578 10/18639 0.2 2.36235741444867 0.205225822582354 0.728798930194563 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 2/1578 10/18639 0.2 2.36235741444867 0.205225822582354 0.728798930194563 GO:0015658 branched-chain amino acid transmembrane transporter activity 2/1578 10/18639 0.2 2.36235741444867 0.205225822582354 0.728798930194563 GO:0015924 mannosyl-oligosaccharide mannosidase activity 2/1578 10/18639 0.2 2.36235741444867 0.205225822582354 0.728798930194563 GO:0016868 intramolecular phosphotransferase activity 2/1578 10/18639 0.2 2.36235741444867 0.205225822582354 0.728798930194563 GO:0033204 ribonuclease P RNA binding 2/1578 10/18639 0.2 2.36235741444867 0.205225822582354 0.728798930194563 GO:0042975 peroxisome proliferator activated receptor binding 2/1578 10/18639 0.2 2.36235741444867 0.205225822582354 0.728798930194563 GO:0043422 protein kinase B binding 2/1578 10/18639 0.2 2.36235741444867 0.205225822582354 0.728798930194563 GO:0047429 nucleoside triphosphate diphosphatase activity 2/1578 10/18639 0.2 2.36235741444867 0.205225822582354 0.728798930194563 GO:0070097 delta-catenin binding 2/1578 10/18639 0.2 2.36235741444867 0.205225822582354 0.728798930194563 GO:0097177 mitochondrial ribosome binding 2/1578 10/18639 0.2 2.36235741444867 0.205225822582354 0.728798930194563 GO:1905394 retromer complex binding 2/1578 10/18639 0.2 2.36235741444867 0.205225822582354 0.728798930194563 GO:0046875 ephrin receptor binding 4/1578 28/18639 0.142857142857143 1.68739815317762 0.208956273519249 0.739818157595178 GO:0004620 phospholipase activity 12/1578 109/18639 0.110091743119266 1.30038022813688 0.210919673504846 0.744533817551538 GO:0140030 modification-dependent protein binding 18/1578 173/18639 0.104046242774566 1.22897206532012 0.212425521227772 0.746458474696907 GO:0050145 nucleoside monophosphate kinase activity 3/1578 19/18639 0.157894736842105 1.86501901140684 0.213997425315992 0.746458474696907 GO:0097001 ceramide binding 3/1578 19/18639 0.157894736842105 1.86501901140684 0.213997425315992 0.746458474696907 GO:0120227 acyl-CoA binding 3/1578 19/18639 0.157894736842105 1.86501901140684 0.213997425315992 0.746458474696907 GO:0030145 manganese ion binding 8/1578 68/18639 0.117647058823529 1.38962200849922 0.215505675942444 0.749502041109563 GO:0061980 regulatory RNA binding 7/1578 58/18639 0.120689655172414 1.42556050871902 0.217401868513898 0.753277238490293 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 6/1578 48/18639 0.125 1.47647338403042 0.217868989249525 0.753277238490293 GO:0003727 single-stranded RNA binding 10/1578 89/18639 0.112359550561798 1.32716708676892 0.219470440940915 0.756595467454208 GO:0051861 glycolipid binding 4/1578 29/18639 0.137931034482759 1.6292120099646 0.227397944269778 0.766080186881574 GO:0016758 hexosyltransferase activity 20/1578 197/18639 0.101522842639594 1.19916620022775 0.228791859950848 0.766080186881574 GO:0031593 polyubiquitin modification-dependent protein binding 7/1578 59/18639 0.11864406779661 1.40139846619836 0.230095097509668 0.766080186881574 GO:0005085 guanyl-nucleotide exchange factor activity 23/1578 230/18639 0.1 1.18117870722433 0.230458325453092 0.766080186881574 GO:0001614 purinergic nucleotide receptor activity 3/1578 20/18639 0.15 1.7717680608365 0.23706917934631 0.766080186881574 GO:0016502 nucleotide receptor activity 3/1578 20/18639 0.15 1.7717680608365 0.23706917934631 0.766080186881574 GO:0016505 peptidase activator activity involved in apoptotic process 3/1578 20/18639 0.15 1.7717680608365 0.23706917934631 0.766080186881574 GO:0140664 ATP-dependent DNA damage sensor activity 3/1578 20/18639 0.15 1.7717680608365 0.23706917934631 0.766080186881574 GO:0140939 histone H4 methyltransferase activity 3/1578 20/18639 0.15 1.7717680608365 0.23706917934631 0.766080186881574 GO:0001851 complement component C3b binding 2/1578 11/18639 0.181818181818182 2.14759764949879 0.237562512239701 0.766080186881574 GO:0003953 NAD+ nucleosidase activity 2/1578 11/18639 0.181818181818182 2.14759764949879 0.237562512239701 0.766080186881574 GO:0008526 phosphatidylinositol transfer activity 2/1578 11/18639 0.181818181818182 2.14759764949879 0.237562512239701 0.766080186881574 GO:0010854 adenylate cyclase regulator activity 2/1578 11/18639 0.181818181818182 2.14759764949879 0.237562512239701 0.766080186881574 GO:0015217 ADP transmembrane transporter activity 2/1578 11/18639 0.181818181818182 2.14759764949879 0.237562512239701 0.766080186881574 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 2/1578 11/18639 0.181818181818182 2.14759764949879 0.237562512239701 0.766080186881574 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 2/1578 11/18639 0.181818181818182 2.14759764949879 0.237562512239701 0.766080186881574 GO:0032794 GTPase activating protein binding 2/1578 11/18639 0.181818181818182 2.14759764949879 0.237562512239701 0.766080186881574 GO:0034056 estrogen response element binding 2/1578 11/18639 0.181818181818182 2.14759764949879 0.237562512239701 0.766080186881574 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 2/1578 11/18639 0.181818181818182 2.14759764949879 0.237562512239701 0.766080186881574 GO:0050998 nitric-oxide synthase binding 2/1578 11/18639 0.181818181818182 2.14759764949879 0.237562512239701 0.766080186881574 GO:0070990 snRNP binding 2/1578 11/18639 0.181818181818182 2.14759764949879 0.237562512239701 0.766080186881574 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/1578 11/18639 0.181818181818182 2.14759764949879 0.237562512239701 0.766080186881574 GO:0140537 transcription regulator activator activity 2/1578 11/18639 0.181818181818182 2.14759764949879 0.237562512239701 0.766080186881574 GO:0005200 structural constituent of cytoskeleton 12/1578 112/18639 0.107142857142857 1.26554861488322 0.238221463156714 0.766080186881574 GO:0008238 exopeptidase activity 11/1578 102/18639 0.107843137254902 1.27382017445762 0.244273706479271 0.766080186881574 GO:0015101 organic cation transmembrane transporter activity 9/1578 81/18639 0.111111111111111 1.31242078580482 0.245518435659733 0.766080186881574 GO:0033192 calmodulin-dependent protein phosphatase activity 9/1578 81/18639 0.111111111111111 1.31242078580482 0.245518435659733 0.766080186881574 GO:0140791 histone H2AXS140 phosphatase activity 9/1578 81/18639 0.111111111111111 1.31242078580482 0.245518435659733 0.766080186881574 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 9/1578 81/18639 0.111111111111111 1.31242078580482 0.245518435659733 0.766080186881574 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 9/1578 81/18639 0.111111111111111 1.31242078580482 0.245518435659733 0.766080186881574 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 9/1578 81/18639 0.111111111111111 1.31242078580482 0.245518435659733 0.766080186881574 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 9/1578 81/18639 0.111111111111111 1.31242078580482 0.245518435659733 0.766080186881574 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 9/1578 81/18639 0.111111111111111 1.31242078580482 0.245518435659733 0.766080186881574 GO:1990439 MAP kinase serine/threonine phosphatase activity 9/1578 81/18639 0.111111111111111 1.31242078580482 0.245518435659733 0.766080186881574 GO:0001965 G-protein alpha-subunit binding 4/1578 30/18639 0.133333333333333 1.57490494296578 0.246227764433202 0.766080186881574 GO:0031624 ubiquitin conjugating enzyme binding 4/1578 30/18639 0.133333333333333 1.57490494296578 0.246227764433202 0.766080186881574 GO:0015605 organophosphate ester transmembrane transporter activity 6/1578 50/18639 0.12 1.4174144486692 0.246263266181609 0.766080186881574 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 5/1578 40/18639 0.125 1.47647338403042 0.247878541312004 0.769075790018033 GO:0004722 protein serine/threonine phosphatase activity 11/1578 103/18639 0.106796116504854 1.26145298829783 0.254254416883784 0.769264700351385 GO:0016757 glycosyltransferase activity 26/1578 267/18639 0.0973782771535581 1.15021147519973 0.255039218918548 0.769264700351385 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 9/1578 82/18639 0.109756097560976 1.29641565427061 0.256805623904152 0.769264700351385 GO:0033549 MAP kinase phosphatase activity 9/1578 82/18639 0.109756097560976 1.29641565427061 0.256805623904152 0.769264700351385 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 3/1578 21/18639 0.142857142857143 1.68739815317762 0.26053594720547 0.769264700351385 GO:0001846 opsonin binding 3/1578 21/18639 0.142857142857143 1.68739815317762 0.26053594720547 0.769264700351385 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 3/1578 21/18639 0.142857142857143 1.68739815317762 0.26053594720547 0.769264700351385 GO:0005021 vascular endothelial growth factor receptor activity 6/1578 51/18639 0.117647058823529 1.38962200849922 0.260843059607846 0.769264700351385 GO:0051213 dioxygenase activity 10/1578 93/18639 0.10752688172043 1.27008463142402 0.261137143125734 0.769264700351385 GO:0042169 SH2 domain binding 5/1578 41/18639 0.121951219512195 1.44046183807846 0.264344438106869 0.769264700351385 GO:0061650 ubiquitin-like protein conjugating enzyme activity 5/1578 41/18639 0.121951219512195 1.44046183807846 0.264344438106869 0.769264700351385 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 9/1578 83/18639 0.108433734939759 1.28079618855651 0.268255542139632 0.769264700351385 GO:0004842 ubiquitin-protein transferase activity 42/1578 449/18639 0.0935412026726058 1.10488876845038 0.269974784609496 0.769264700351385 GO:0003995 acyl-CoA dehydrogenase activity 2/1578 12/18639 0.166666666666667 1.96863117870722 0.270123482566135 0.769264700351385 GO:0004859 phospholipase inhibitor activity 2/1578 12/18639 0.166666666666667 1.96863117870722 0.270123482566135 0.769264700351385 GO:0005025 transforming growth factor beta receptor activity, type I 2/1578 12/18639 0.166666666666667 1.96863117870722 0.270123482566135 0.769264700351385 GO:0005026 transforming growth factor beta receptor activity, type II 2/1578 12/18639 0.166666666666667 1.96863117870722 0.270123482566135 0.769264700351385 GO:0005078 MAP-kinase scaffold activity 2/1578 12/18639 0.166666666666667 1.96863117870722 0.270123482566135 0.769264700351385 GO:0005095 GTPase inhibitor activity 2/1578 12/18639 0.166666666666667 1.96863117870722 0.270123482566135 0.769264700351385 GO:0005165 neurotrophin receptor binding 2/1578 12/18639 0.166666666666667 1.96863117870722 0.270123482566135 0.769264700351385 GO:0005247 voltage-gated chloride channel activity 2/1578 12/18639 0.166666666666667 1.96863117870722 0.270123482566135 0.769264700351385 GO:0008179 adenylate cyclase binding 2/1578 12/18639 0.166666666666667 1.96863117870722 0.270123482566135 0.769264700351385 GO:0008603 cAMP-dependent protein kinase regulator activity 2/1578 12/18639 0.166666666666667 1.96863117870722 0.270123482566135 0.769264700351385 GO:0016361 activin receptor activity, type I 2/1578 12/18639 0.166666666666667 1.96863117870722 0.270123482566135 0.769264700351385 GO:0016362 activin receptor activity, type II 2/1578 12/18639 0.166666666666667 1.96863117870722 0.270123482566135 0.769264700351385 GO:0017002 activin receptor activity 2/1578 12/18639 0.166666666666667 1.96863117870722 0.270123482566135 0.769264700351385 GO:0017166 vinculin binding 2/1578 12/18639 0.166666666666667 1.96863117870722 0.270123482566135 0.769264700351385 GO:0034452 dynactin binding 2/1578 12/18639 0.166666666666667 1.96863117870722 0.270123482566135 0.769264700351385 GO:0035014 phosphatidylinositol 3-kinase regulator activity 2/1578 12/18639 0.166666666666667 1.96863117870722 0.270123482566135 0.769264700351385 GO:0035197 siRNA binding 2/1578 12/18639 0.166666666666667 1.96863117870722 0.270123482566135 0.769264700351385 GO:0035251 UDP-glucosyltransferase activity 2/1578 12/18639 0.166666666666667 1.96863117870722 0.270123482566135 0.769264700351385 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 2/1578 12/18639 0.166666666666667 1.96863117870722 0.270123482566135 0.769264700351385 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 2/1578 12/18639 0.166666666666667 1.96863117870722 0.270123482566135 0.769264700351385 GO:0097677 STAT family protein binding 2/1578 12/18639 0.166666666666667 1.96863117870722 0.270123482566135 0.769264700351385 GO:0004857 enzyme inhibitor activity 39/1578 416/18639 0.09375 1.10735503802281 0.274297027254471 0.77926794007957 GO:0042826 histone deacetylase binding 13/1578 127/18639 0.102362204724409 1.20908056645011 0.277907045851161 0.786343140502817 GO:0017018 myosin phosphatase activity 9/1578 84/18639 0.107142857142857 1.26554861488322 0.279855369809738 0.786343140502817 GO:0035198 miRNA binding 5/1578 42/18639 0.119047619047619 1.40616512764802 0.281047204184936 0.786343140502817 GO:0042056 chemoattractant activity 5/1578 42/18639 0.119047619047619 1.40616512764802 0.281047204184936 0.786343140502817 GO:0043175 RNA polymerase core enzyme binding 5/1578 42/18639 0.119047619047619 1.40616512764802 0.281047204184936 0.786343140502817 GO:0051879 Hsp90 protein binding 5/1578 42/18639 0.119047619047619 1.40616512764802 0.281047204184936 0.786343140502817 GO:0016881 acid-amino acid ligase activity 3/1578 22/18639 0.136363636363636 1.61069823712409 0.284278750200582 0.786343140502817 GO:0008378 galactosyltransferase activity 4/1578 32/18639 0.125 1.47647338403042 0.284790942319511 0.786343140502817 GO:0031369 translation initiation factor binding 4/1578 32/18639 0.125 1.47647338403042 0.284790942319511 0.786343140502817 GO:0071813 lipoprotein particle binding 4/1578 32/18639 0.125 1.47647338403042 0.284790942319511 0.786343140502817 GO:0071814 protein-lipid complex binding 4/1578 32/18639 0.125 1.47647338403042 0.284790942319511 0.786343140502817 GO:0120015 sterol transfer activity 4/1578 32/18639 0.125 1.47647338403042 0.284790942319511 0.786343140502817 GO:0019208 phosphatase regulator activity 12/1578 117/18639 0.102564102564103 1.21146534074291 0.286433669818207 0.789031067092678 GO:0070851 growth factor receptor binding 14/1578 139/18639 0.100719424460432 1.18967639576552 0.287872210702402 0.791145306335972 GO:0034212 protein N-acetyltransferase activity 6/1578 53/18639 0.113207547169811 1.33718344214076 0.290627633402672 0.796860418097092 GO:0035091 phosphatidylinositol binding 27/1578 284/18639 0.0950704225352113 1.12295158785412 0.291744412929974 0.79806650311935 GO:0042578 phosphoric ester hydrolase activity 34/1578 363/18639 0.09366391184573 1.10633818307513 0.292794589491679 0.798231251070909 GO:0016791 phosphatase activity 26/1578 273/18639 0.0952380952380952 1.12493210211841 0.293158720707128 0.798231251070909 GO:0019888 protein phosphatase regulator activity 11/1578 107/18639 0.102803738317757 1.21429586723997 0.295476414732353 0.801823758481659 GO:0035591 signaling adaptor activity 13/1578 129/18639 0.10077519379845 1.19033513131134 0.296899272428999 0.801823758481659 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 5/1578 43/18639 0.116279069767442 1.37346361305155 0.297946663588329 0.801823758481659 GO:0044183 protein folding chaperone 8/1578 75/18639 0.106666666666667 1.25992395437262 0.300820952401626 0.801823758481659 GO:0008035 high-density lipoprotein particle binding 2/1578 13/18639 0.153846153846154 1.81719801111436 0.302639162446428 0.801823758481659 GO:0015651 quaternary ammonium group transmembrane transporter activity 2/1578 13/18639 0.153846153846154 1.81719801111436 0.302639162446428 0.801823758481659 GO:0035673 oligopeptide transmembrane transporter activity 2/1578 13/18639 0.153846153846154 1.81719801111436 0.302639162446428 0.801823758481659 GO:0043560 insulin receptor substrate binding 2/1578 13/18639 0.153846153846154 1.81719801111436 0.302639162446428 0.801823758481659 GO:0051011 microtubule minus-end binding 2/1578 13/18639 0.153846153846154 1.81719801111436 0.302639162446428 0.801823758481659 GO:0070123 transforming growth factor beta receptor activity, type III 2/1578 13/18639 0.153846153846154 1.81719801111436 0.302639162446428 0.801823758481659 GO:0097157 pre-mRNA intronic binding 2/1578 13/18639 0.153846153846154 1.81719801111436 0.302639162446428 0.801823758481659 GO:0140852 histone ubiquitin ligase activity 2/1578 13/18639 0.153846153846154 1.81719801111436 0.302639162446428 0.801823758481659 GO:0050661 NADP binding 6/1578 54/18639 0.111111111111111 1.31242078580482 0.305776208921197 0.803875393866823 GO:0016298 lipase activity 13/1578 130/18639 0.1 1.18117870722433 0.306532548261913 0.803875393866823 GO:0003887 DNA-directed DNA polymerase activity 3/1578 23/18639 0.130434782608696 1.54066787898826 0.308186325723328 0.803875393866823 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 3/1578 23/18639 0.130434782608696 1.54066787898826 0.308186325723328 0.803875393866823 GO:0031681 G-protein beta-subunit binding 3/1578 23/18639 0.130434782608696 1.54066787898826 0.308186325723328 0.803875393866823 GO:0070577 lysine-acetylated histone binding 3/1578 23/18639 0.130434782608696 1.54066787898826 0.308186325723328 0.803875393866823 GO:0140103 catalytic activity, acting on a glycoprotein 3/1578 23/18639 0.130434782608696 1.54066787898826 0.308186325723328 0.803875393866823 GO:0019843 rRNA binding 7/1578 65/18639 0.107692307692308 1.27203860778005 0.310622458639648 0.808441233413123 GO:0030020 extracellular matrix structural constituent conferring tensile strength 5/1578 44/18639 0.113636363636364 1.34224853093674 0.31500329334222 0.815536282123909 GO:0043014 alpha-tubulin binding 5/1578 44/18639 0.113636363636364 1.34224853093674 0.31500329334222 0.815536282123909 GO:0008081 phosphoric diester hydrolase activity 9/1578 87/18639 0.103448275862069 1.22190900747345 0.315423701991944 0.815536282123909 GO:0140313 molecular sequestering activity 6/1578 55/18639 0.109090909090909 1.28855858969927 0.321058476962706 0.828288718466149 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 4/1578 34/18639 0.117647058823529 1.38962200849922 0.324141002038867 0.832970876494205 GO:0003724 RNA helicase activity 8/1578 77/18639 0.103896103896104 1.22719865685645 0.326543035808597 0.832970876494205 GO:0005540 hyaluronic acid binding 3/1578 24/18639 0.125 1.47647338403042 0.332155484033416 0.832970876494205 GO:0035035 histone acetyltransferase binding 3/1578 24/18639 0.125 1.47647338403042 0.332155484033416 0.832970876494205 GO:0070840 dynein complex binding 3/1578 24/18639 0.125 1.47647338403042 0.332155484033416 0.832970876494205 GO:0140033 acetylation-dependent protein binding 3/1578 24/18639 0.125 1.47647338403042 0.332155484033416 0.832970876494205 GO:0140612 DNA damage sensor activity 3/1578 24/18639 0.125 1.47647338403042 0.332155484033416 0.832970876494205 GO:0051539 4 iron, 4 sulfur cluster binding 5/1578 45/18639 0.111111111111111 1.31242078580482 0.332178434339144 0.832970876494205 GO:0005161 platelet-derived growth factor receptor binding 2/1578 14/18639 0.142857142857143 1.68739815317762 0.334883965613446 0.832970876494205 GO:0005347 ATP transmembrane transporter activity 2/1578 14/18639 0.142857142857143 1.68739815317762 0.334883965613446 0.832970876494205 GO:0016530 metallochaperone activity 2/1578 14/18639 0.142857142857143 1.68739815317762 0.334883965613446 0.832970876494205 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 2/1578 14/18639 0.142857142857143 1.68739815317762 0.334883965613446 0.832970876494205 GO:0030983 mismatched DNA binding 2/1578 14/18639 0.142857142857143 1.68739815317762 0.334883965613446 0.832970876494205 GO:0042813 Wnt receptor activity 2/1578 14/18639 0.142857142857143 1.68739815317762 0.334883965613446 0.832970876494205 GO:0046030 inositol trisphosphate phosphatase activity 2/1578 14/18639 0.142857142857143 1.68739815317762 0.334883965613446 0.832970876494205 GO:0098821 BMP receptor activity 2/1578 14/18639 0.142857142857143 1.68739815317762 0.334883965613446 0.832970876494205 GO:0098847 sequence-specific single stranded DNA binding 2/1578 14/18639 0.142857142857143 1.68739815317762 0.334883965613446 0.832970876494205 GO:1902936 phosphatidylinositol bisphosphate binding 11/1578 111/18639 0.0990990990990991 1.1705374576097 0.338343503750389 0.838750261914631 GO:0016500 protein-hormone receptor activity 7/1578 67/18639 0.104477611940299 1.23406730605527 0.338630300823889 0.838750261914631 GO:0019199 transmembrane receptor protein kinase activity 8/1578 78/18639 0.102564102564103 1.21146534074291 0.339547068655642 0.839257848941304 GO:0008186 ATP-dependent activity, acting on RNA 8/1578 79/18639 0.10126582278481 1.19613033642971 0.352624784025916 0.869758620013714 GO:0001848 complement binding 3/1578 25/18639 0.12 1.4174144486692 0.356091281123965 0.870478792066165 GO:0000993 RNA polymerase II complex binding 4/1578 36/18639 0.111111111111111 1.31242078580482 0.363808647576923 0.870478792066165 GO:0005484 SNAP receptor activity 4/1578 36/18639 0.111111111111111 1.31242078580482 0.363808647576923 0.870478792066165 GO:0044390 ubiquitin-like protein conjugating enzyme binding 4/1578 36/18639 0.111111111111111 1.31242078580482 0.363808647576923 0.870478792066165 GO:0140789 histone phosphatase activity 13/1578 136/18639 0.0955882352941176 1.12906788190561 0.365815838364859 0.870478792066165 GO:0140098 catalytic activity, acting on RNA 35/1578 387/18639 0.0904392764857881 1.06824947681787 0.366092624224935 0.870478792066165 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/1578 15/18639 0.133333333333333 1.57490494296578 0.366670782706778 0.870478792066165 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/1578 15/18639 0.133333333333333 1.57490494296578 0.366670782706778 0.870478792066165 GO:0005041 low-density lipoprotein particle receptor activity 2/1578 15/18639 0.133333333333333 1.57490494296578 0.366670782706778 0.870478792066165 GO:0005523 tropomyosin binding 2/1578 15/18639 0.133333333333333 1.57490494296578 0.366670782706778 0.870478792066165 GO:0016846 carbon-sulfur lyase activity 2/1578 15/18639 0.133333333333333 1.57490494296578 0.366670782706778 0.870478792066165 GO:0033130 acetylcholine receptor binding 2/1578 15/18639 0.133333333333333 1.57490494296578 0.366670782706778 0.870478792066165 GO:0047372 monoacylglycerol lipase activity 2/1578 15/18639 0.133333333333333 1.57490494296578 0.366670782706778 0.870478792066165 GO:0048531 beta-1,3-galactosyltransferase activity 2/1578 15/18639 0.133333333333333 1.57490494296578 0.366670782706778 0.870478792066165 GO:0050780 dopamine receptor binding 2/1578 15/18639 0.133333333333333 1.57490494296578 0.366670782706778 0.870478792066165 GO:0001784 phosphotyrosine residue binding 5/1578 47/18639 0.106382978723404 1.25657309279185 0.366735024543458 0.870478792066165 GO:0061733 protein-lysine-acetyltransferase activity 5/1578 47/18639 0.106382978723404 1.25657309279185 0.366735024543458 0.870478792066165 GO:0140359 ABC-type transporter activity 5/1578 47/18639 0.106382978723404 1.25657309279185 0.366735024543458 0.870478792066165 GO:0002039 p53 binding 7/1578 69/18639 0.101449275362319 1.19829723921309 0.366944834314575 0.870478792066165 GO:0001664 G protein-coupled receptor binding 27/1578 297/18639 0.0909090909090909 1.0737988247494 0.378049989544368 0.879496545718033 GO:0004112 cyclic-nucleotide phosphodiesterase activity 3/1578 26/18639 0.115384615384615 1.36289850833577 0.379907041971684 0.879496545718033 GO:0008157 protein phosphatase 1 binding 3/1578 26/18639 0.115384615384615 1.36289850833577 0.379907041971684 0.879496545718033 GO:0008198 ferrous iron binding 3/1578 26/18639 0.115384615384615 1.36289850833577 0.379907041971684 0.879496545718033 GO:0015216 purine nucleotide transmembrane transporter activity 3/1578 26/18639 0.115384615384615 1.36289850833577 0.379907041971684 0.879496545718033 GO:0034237 protein kinase A regulatory subunit binding 3/1578 26/18639 0.115384615384615 1.36289850833577 0.379907041971684 0.879496545718033 GO:0043548 phosphatidylinositol 3-kinase binding 3/1578 26/18639 0.115384615384615 1.36289850833577 0.379907041971684 0.879496545718033 GO:0070006 metalloaminopeptidase activity 3/1578 26/18639 0.115384615384615 1.36289850833577 0.379907041971684 0.879496545718033 GO:0097602 cullin family protein binding 3/1578 26/18639 0.115384615384615 1.36289850833577 0.379907041971684 0.879496545718033 GO:0004879 nuclear receptor activity 6/1578 59/18639 0.101694915254237 1.20119868531288 0.382983483742259 0.879496545718033 GO:0045309 protein phosphorylated amino acid binding 6/1578 59/18639 0.101694915254237 1.20119868531288 0.382983483742259 0.879496545718033 GO:0070063 RNA polymerase binding 6/1578 59/18639 0.101694915254237 1.20119868531288 0.382983483742259 0.879496545718033 GO:0043394 proteoglycan binding 4/1578 37/18639 0.108108108108108 1.27694995375604 0.383626850013692 0.879496545718033 GO:0038187 pattern recognition receptor activity 5/1578 48/18639 0.104166666666667 1.23039448669202 0.384045028647404 0.879496545718033 GO:0140693 molecular condensate scaffold activity 5/1578 48/18639 0.104166666666667 1.23039448669202 0.384045028647404 0.879496545718033 GO:0051219 phosphoprotein binding 9/1578 93/18639 0.0967741935483871 1.14307616828161 0.388832070253606 0.879496545718033 GO:0003688 DNA replication origin binding 2/1578 16/18639 0.125 1.47647338403042 0.397846089787914 0.879496545718033 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 2/1578 16/18639 0.125 1.47647338403042 0.397846089787914 0.879496545718033 GO:0004708 MAP kinase kinase activity 2/1578 16/18639 0.125 1.47647338403042 0.397846089787914 0.879496545718033 GO:0005024 transforming growth factor beta receptor activity 2/1578 16/18639 0.125 1.47647338403042 0.397846089787914 0.879496545718033 GO:0005159 insulin-like growth factor receptor binding 2/1578 16/18639 0.125 1.47647338403042 0.397846089787914 0.879496545718033 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/1578 16/18639 0.125 1.47647338403042 0.397846089787914 0.879496545718033 GO:0034450 ubiquitin-ubiquitin ligase activity 2/1578 16/18639 0.125 1.47647338403042 0.397846089787914 0.879496545718033 GO:0055102 lipase inhibitor activity 2/1578 16/18639 0.125 1.47647338403042 0.397846089787914 0.879496545718033 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 2/1578 16/18639 0.125 1.47647338403042 0.397846089787914 0.879496545718033 GO:0004714 transmembrane receptor protein tyrosine kinase activity 6/1578 60/18639 0.1 1.18117870722433 0.39853381069504 0.879496545718033 GO:0098531 ligand-modulated transcription factor activity 6/1578 60/18639 0.1 1.18117870722433 0.39853381069504 0.879496545718033 GO:1901981 phosphatidylinositol phosphate binding 17/1578 185/18639 0.0918918918918919 1.08540746069263 0.398779856619878 0.879496545718033 GO:0005543 phospholipid binding 44/1578 497/18639 0.0885311871227364 1.04571153154669 0.400267268484244 0.879496545718033 GO:0016410 N-acyltransferase activity 9/1578 94/18639 0.0957446808510638 1.13091578351266 0.401208857384269 0.879496545718033 GO:0001222 transcription corepressor binding 5/1578 49/18639 0.102040816326531 1.20528439512687 0.401330908902716 0.879496545718033 GO:0005004 GPI-linked ephrin receptor activity 5/1578 49/18639 0.102040816326531 1.20528439512687 0.401330908902716 0.879496545718033 GO:0005008 hepatocyte growth factor receptor activity 5/1578 49/18639 0.102040816326531 1.20528439512687 0.401330908902716 0.879496545718033 GO:0005009 insulin receptor activity 5/1578 49/18639 0.102040816326531 1.20528439512687 0.401330908902716 0.879496545718033 GO:0005011 macrophage colony-stimulating factor receptor activity 5/1578 49/18639 0.102040816326531 1.20528439512687 0.401330908902716 0.879496545718033 GO:0005018 platelet-derived growth factor alpha-receptor activity 5/1578 49/18639 0.102040816326531 1.20528439512687 0.401330908902716 0.879496545718033 GO:0005020 stem cell factor receptor activity 5/1578 49/18639 0.102040816326531 1.20528439512687 0.401330908902716 0.879496545718033 GO:0008288 boss receptor activity 5/1578 49/18639 0.102040816326531 1.20528439512687 0.401330908902716 0.879496545718033 GO:0036332 placental growth factor receptor activity 5/1578 49/18639 0.102040816326531 1.20528439512687 0.401330908902716 0.879496545718033 GO:0038062 protein tyrosine kinase collagen receptor activity 5/1578 49/18639 0.102040816326531 1.20528439512687 0.401330908902716 0.879496545718033 GO:0060175 brain-derived neurotrophic factor receptor activity 5/1578 49/18639 0.102040816326531 1.20528439512687 0.401330908902716 0.879496545718033 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 3/1578 27/18639 0.111111111111111 1.31242078580482 0.403524263506832 0.881027975323249 GO:0023026 MHC class II protein complex binding 3/1578 27/18639 0.111111111111111 1.31242078580482 0.403524263506832 0.881027975323249 GO:0004713 protein tyrosine kinase activity 13/1578 140/18639 0.0928571428571429 1.09680879956545 0.406235829253754 0.881236880334182 GO:0051015 actin filament binding 19/1578 209/18639 0.0909090909090909 1.0737988247494 0.407587885447677 0.881236880334182 GO:0004721 phosphoprotein phosphatase activity 16/1578 175/18639 0.0914285714285714 1.07993481803368 0.41198264396037 0.881236880334182 GO:0015026 coreceptor activity 6/1578 61/18639 0.0983606557377049 1.16181512186 0.414062452151578 0.881236880334182 GO:0005006 epidermal growth factor receptor activity 5/1578 50/18639 0.1 1.18117870722433 0.418560646982838 0.881236880334182 GO:0005007 fibroblast growth factor receptor activity 5/1578 50/18639 0.1 1.18117870722433 0.418560646982838 0.881236880334182 GO:0005017 platelet-derived growth factor receptor activity 5/1578 50/18639 0.1 1.18117870722433 0.418560646982838 0.881236880334182 GO:0005019 platelet-derived growth factor beta-receptor activity 5/1578 50/18639 0.1 1.18117870722433 0.418560646982838 0.881236880334182 GO:0032813 tumor necrosis factor receptor superfamily binding 5/1578 50/18639 0.1 1.18117870722433 0.418560646982838 0.881236880334182 GO:0000217 DNA secondary structure binding 4/1578 39/18639 0.102564102564103 1.21146534074291 0.422989273865329 0.881236880334182 GO:0016776 phosphotransferase activity, phosphate group as acceptor 4/1578 39/18639 0.102564102564103 1.21146534074291 0.422989273865329 0.881236880334182 GO:0004521 RNA endonuclease activity 7/1578 73/18639 0.0958904109589041 1.13263711651649 0.423862104791508 0.881236880334182 GO:0016866 intramolecular transferase activity 3/1578 28/18639 0.107142857142857 1.26554861488322 0.426872422305341 0.881236880334182 GO:0036408 histone H3K14 acetyltransferase activity 3/1578 28/18639 0.107142857142857 1.26554861488322 0.426872422305341 0.881236880334182 GO:0046625 sphingolipid binding 3/1578 28/18639 0.107142857142857 1.26554861488322 0.426872422305341 0.881236880334182 GO:0097718 disordered domain specific binding 3/1578 28/18639 0.107142857142857 1.26554861488322 0.426872422305341 0.881236880334182 GO:0004029 aldehyde dehydrogenase (NAD+) activity 2/1578 17/18639 0.117647058823529 1.38962200849922 0.42828560850847 0.881236880334182 GO:0004659 prenyltransferase activity 2/1578 17/18639 0.117647058823529 1.38962200849922 0.42828560850847 0.881236880334182 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 2/1578 17/18639 0.117647058823529 1.38962200849922 0.42828560850847 0.881236880334182 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/1578 17/18639 0.117647058823529 1.38962200849922 0.42828560850847 0.881236880334182 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/1578 17/18639 0.117647058823529 1.38962200849922 0.42828560850847 0.881236880334182 GO:0015278 intracellularly gated calcium channel activity 2/1578 17/18639 0.117647058823529 1.38962200849922 0.42828560850847 0.881236880334182 GO:0016018 cyclosporin A binding 2/1578 17/18639 0.117647058823529 1.38962200849922 0.42828560850847 0.881236880334182 GO:0017110 nucleoside diphosphate phosphatase activity 2/1578 17/18639 0.117647058823529 1.38962200849922 0.42828560850847 0.881236880334182 GO:0019198 transmembrane receptor protein phosphatase activity 2/1578 17/18639 0.117647058823529 1.38962200849922 0.42828560850847 0.881236880334182 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 2/1578 17/18639 0.117647058823529 1.38962200849922 0.42828560850847 0.881236880334182 GO:0032183 SUMO binding 2/1578 17/18639 0.117647058823529 1.38962200849922 0.42828560850847 0.881236880334182 GO:0032977 membrane insertase activity 2/1578 17/18639 0.117647058823529 1.38962200849922 0.42828560850847 0.881236880334182 GO:0036041 long-chain fatty acid binding 2/1578 17/18639 0.117647058823529 1.38962200849922 0.42828560850847 0.881236880334182 GO:0038191 neuropilin binding 2/1578 17/18639 0.117647058823529 1.38962200849922 0.42828560850847 0.881236880334182 GO:0046965 nuclear retinoid X receptor binding 2/1578 17/18639 0.117647058823529 1.38962200849922 0.42828560850847 0.881236880334182 GO:0048038 quinone binding 2/1578 17/18639 0.117647058823529 1.38962200849922 0.42828560850847 0.881236880334182 GO:0070402 NADPH binding 2/1578 17/18639 0.117647058823529 1.38962200849922 0.42828560850847 0.881236880334182 GO:0015179 L-amino acid transmembrane transporter activity 6/1578 62/18639 0.0967741935483871 1.14307616828161 0.429546285442493 0.882291063652787 GO:0004674 protein serine/threonine kinase activity 38/1578 433/18639 0.0877598152424942 1.03660025114376 0.432678976723842 0.887180023578104 GO:0005010 insulin-like growth factor receptor activity 5/1578 51/18639 0.0980392156862745 1.15801834041601 0.43570386300186 0.890285709669311 GO:0005030 neurotrophin receptor activity 5/1578 51/18639 0.0980392156862745 1.15801834041601 0.43570386300186 0.890285709669311 GO:0003684 damaged DNA binding 7/1578 74/18639 0.0945945945945946 1.11733120953653 0.438042486822765 0.89043464131731 GO:0035064 methylated histone binding 7/1578 74/18639 0.0945945945945946 1.11733120953653 0.438042486822765 0.89043464131731 GO:0048029 monosaccharide binding 7/1578 74/18639 0.0945945945945946 1.11733120953653 0.438042486822765 0.89043464131731 GO:0004386 helicase activity 14/1578 155/18639 0.0903225806451613 1.06687109039617 0.440974088362169 0.892517399979975 GO:0061791 GTPase motor activity 4/1578 40/18639 0.1 1.18117870722433 0.442446021926809 0.892517399979975 GO:0071949 FAD binding 4/1578 40/18639 0.1 1.18117870722433 0.442446021926809 0.892517399979975 GO:1990606 membrane scission GTPase motor activity 4/1578 40/18639 0.1 1.18117870722433 0.442446021926809 0.892517399979975 GO:0019902 phosphatase binding 17/1578 190/18639 0.0894736842105263 1.05684410646388 0.442852145028232 0.892517399979975 GO:0003785 actin monomer binding 3/1578 29/18639 0.103448275862069 1.22190900747345 0.449888708232522 0.899014893230751 GO:0010484 histone H3 acetyltransferase activity 3/1578 29/18639 0.103448275862069 1.22190900747345 0.449888708232522 0.899014893230751 GO:0035250 UDP-galactosyltransferase activity 3/1578 29/18639 0.103448275862069 1.22190900747345 0.449888708232522 0.899014893230751 GO:0043236 laminin binding 3/1578 29/18639 0.103448275862069 1.22190900747345 0.449888708232522 0.899014893230751 GO:0106222 lncRNA binding 3/1578 29/18639 0.103448275862069 1.22190900747345 0.449888708232522 0.899014893230751 GO:0008194 UDP-glycosyltransferase activity 13/1578 145/18639 0.0896551724137931 1.05898780647699 0.456990911842864 0.901256848002179 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 2/1578 18/18639 0.111111111111111 1.31242078580482 0.457890459672014 0.901256848002179 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/1578 18/18639 0.111111111111111 1.31242078580482 0.457890459672014 0.901256848002179 GO:0004706 JUN kinase kinase kinase activity 2/1578 18/18639 0.111111111111111 1.31242078580482 0.457890459672014 0.901256848002179 GO:0008308 voltage-gated monoatomic anion channel activity 2/1578 18/18639 0.111111111111111 1.31242078580482 0.457890459672014 0.901256848002179 GO:0008525 phosphatidylcholine transporter activity 2/1578 18/18639 0.111111111111111 1.31242078580482 0.457890459672014 0.901256848002179 GO:0017128 phospholipid scramblase activity 2/1578 18/18639 0.111111111111111 1.31242078580482 0.457890459672014 0.901256848002179 GO:0070064 proline-rich region binding 2/1578 18/18639 0.111111111111111 1.31242078580482 0.457890459672014 0.901256848002179 GO:0098641 cadherin binding involved in cell-cell adhesion 2/1578 18/18639 0.111111111111111 1.31242078580482 0.457890459672014 0.901256848002179 GO:0001530 lipopolysaccharide binding 4/1578 41/18639 0.0975609756097561 1.15236947046277 0.461700247204641 0.907240985757119 GO:0140034 methylation-dependent protein binding 7/1578 76/18639 0.0921052631578947 1.08792775665399 0.466222948838434 0.91327601744894 GO:0005126 cytokine receptor binding 24/1578 275/18639 0.0872727272727273 1.03084687175942 0.469322932816191 0.91327601744894 GO:0005003 ephrin receptor activity 5/1578 53/18639 0.0943396226415094 1.1143195351173 0.469617731678147 0.91327601744894 GO:0005005 transmembrane-ephrin receptor activity 5/1578 53/18639 0.0943396226415094 1.1143195351173 0.469617731678147 0.91327601744894 GO:0038064 collagen receptor activity 5/1578 53/18639 0.0943396226415094 1.1143195351173 0.469617731678147 0.91327601744894 GO:1901505 carbohydrate derivative transmembrane transporter activity 5/1578 53/18639 0.0943396226415094 1.1143195351173 0.469617731678147 0.91327601744894 GO:0015215 nucleotide transmembrane transporter activity 3/1578 30/18639 0.1 1.18117870722433 0.472517701988001 0.91327601744894 GO:0043995 histone H4K5 acetyltransferase activity 3/1578 30/18639 0.1 1.18117870722433 0.472517701988001 0.91327601744894 GO:0043996 histone H4K8 acetyltransferase activity 3/1578 30/18639 0.1 1.18117870722433 0.472517701988001 0.91327601744894 GO:0043997 histone H4K12 acetyltransferase activity 3/1578 30/18639 0.1 1.18117870722433 0.472517701988001 0.91327601744894 GO:0160215 deacylase activity 6/1578 65/18639 0.0923076923076923 1.09031880666862 0.47551257578505 0.917560273077863 GO:0004402 histone acetyltransferase activity 4/1578 42/18639 0.0952380952380952 1.12493210211841 0.480716356996188 0.922318730680696 GO:0019894 kinesin binding 4/1578 42/18639 0.0952380952380952 1.12493210211841 0.480716356996188 0.922318730680696 GO:0044325 transmembrane transporter binding 12/1578 136/18639 0.0882352941176471 1.04221650637441 0.484705819691651 0.922318730680696 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 2/1578 19/18639 0.105263157894737 1.24334600760456 0.486583757831546 0.922318730680696 GO:0005346 purine ribonucleotide transmembrane transporter activity 2/1578 19/18639 0.105263157894737 1.24334600760456 0.486583757831546 0.922318730680696 GO:0008574 plus-end-directed microtubule motor activity 2/1578 19/18639 0.105263157894737 1.24334600760456 0.486583757831546 0.922318730680696 GO:0015245 fatty acid transmembrane transporter activity 2/1578 19/18639 0.105263157894737 1.24334600760456 0.486583757831546 0.922318730680696 GO:0042577 lipid phosphatase activity 2/1578 19/18639 0.105263157894737 1.24334600760456 0.486583757831546 0.922318730680696 GO:0046527 glucosyltransferase activity 2/1578 19/18639 0.105263157894737 1.24334600760456 0.486583757831546 0.922318730680696 GO:0046624 sphingolipid transporter activity 2/1578 19/18639 0.105263157894737 1.24334600760456 0.486583757831546 0.922318730680696 GO:0140036 ubiquitin-modified protein reader activity 2/1578 19/18639 0.105263157894737 1.24334600760456 0.486583757831546 0.922318730680696 GO:0008201 heparin binding 15/1578 172/18639 0.0872093023255814 1.03009770978866 0.491719318547745 0.930557105245251 GO:0061135 endopeptidase regulator activity 16/1578 184/18639 0.0869565217391304 1.02711191932551 0.493709640471511 0.931732081057446 GO:0008327 methyl-CpG binding 3/1578 31/18639 0.0967741935483871 1.14307616828161 0.494711011655607 0.931732081057446 GO:0070273 phosphatidylinositol-4-phosphate binding 3/1578 31/18639 0.0967741935483871 1.14307616828161 0.494711011655607 0.931732081057446 GO:0033293 monocarboxylic acid binding 7/1578 79/18639 0.0886075949367089 1.04661404437599 0.507807614734734 0.937165882464833 GO:0010851 cyclase regulator activity 2/1578 20/18639 0.1 1.18117870722433 0.514307599885462 0.937165882464833 GO:0016408 C-acyltransferase activity 2/1578 20/18639 0.1 1.18117870722433 0.514307599885462 0.937165882464833 GO:0042288 MHC class I protein binding 2/1578 20/18639 0.1 1.18117870722433 0.514307599885462 0.937165882464833 GO:0061608 nuclear import signal receptor activity 2/1578 20/18639 0.1 1.18117870722433 0.514307599885462 0.937165882464833 GO:0004519 endonuclease activity 11/1578 127/18639 0.0866141732283465 1.02306817161163 0.514543077118155 0.937165882464833 GO:0043425 bHLH transcription factor binding 3/1578 32/18639 0.09375 1.10735503802281 0.516426880897273 0.937165882464833 GO:0070717 poly-purine tract binding 3/1578 32/18639 0.09375 1.10735503802281 0.516426880897273 0.937165882464833 GO:0001223 transcription coactivator binding 4/1578 44/18639 0.0909090909090909 1.0737988247494 0.517907833899907 0.937165882464833 GO:0019205 nucleobase-containing compound kinase activity 4/1578 44/18639 0.0909090909090909 1.0737988247494 0.517907833899907 0.937165882464833 GO:0005548 phospholipid transporter activity 6/1578 68/18639 0.0882352941176471 1.04221650637441 0.520341108819033 0.937165882464833 GO:0048306 calcium-dependent protein binding 7/1578 80/18639 0.0875 1.03353136882129 0.521428605358542 0.937165882464833 GO:0008080 N-acetyltransferase activity 6/1578 69/18639 0.0869565217391304 1.02711191932551 0.534950277819458 0.937165882464833 GO:0015932 nucleobase-containing compound transmembrane transporter activity 5/1578 57/18639 0.087719298245614 1.0361216730038 0.53526256663725 0.937165882464833 GO:0008009 chemokine activity 4/1578 45/18639 0.0888888888888889 1.04993662864385 0.53602777532047 0.937165882464833 GO:0046915 transition metal ion transmembrane transporter activity 4/1578 45/18639 0.0888888888888889 1.04993662864385 0.53602777532047 0.937165882464833 GO:0140416 transcription regulator inhibitor activity 3/1578 33/18639 0.0909090909090909 1.0737988247494 0.537629779300328 0.937165882464833 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 2/1578 21/18639 0.0952380952380952 1.12493210211841 0.541020405430724 0.937165882464833 GO:0009931 calcium-dependent protein serine/threonine kinase activity 2/1578 21/18639 0.0952380952380952 1.12493210211841 0.541020405430724 0.937165882464833 GO:0035613 RNA stem-loop binding 2/1578 21/18639 0.0952380952380952 1.12493210211841 0.541020405430724 0.937165882464833 GO:0072542 protein phosphatase activator activity 2/1578 21/18639 0.0952380952380952 1.12493210211841 0.541020405430724 0.937165882464833 GO:1904047 S-adenosyl-L-methionine binding 2/1578 21/18639 0.0952380952380952 1.12493210211841 0.541020405430724 0.937165882464833 GO:0042562 hormone binding 8/1578 94/18639 0.0851063829787234 1.00525847423348 0.547484844667881 0.937165882464833 GO:0008408 3'-5' exonuclease activity 5/1578 58/18639 0.0862068965517241 1.01825750622787 0.551095307616143 0.937165882464833 GO:0008376 acetylgalactosaminyltransferase activity 3/1578 34/18639 0.0882352941176471 1.04221650637441 0.558289983551436 0.937165882464833 GO:0140299 molecular sensor activity 6/1578 71/18639 0.0845070422535211 0.998179189203663 0.563579262369833 0.937165882464833 GO:0005201 extracellular matrix structural constituent 14/1578 168/18639 0.0833333333333333 0.984315589353612 0.56523852887863 0.937165882464833 GO:0019903 protein phosphatase binding 12/1578 144/18639 0.0833333333333333 0.984315589353612 0.566561020728662 0.937165882464833 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/1578 22/18639 0.0909090909090909 1.0737988247494 0.566694570953737 0.937165882464833 GO:0031683 G-protein beta/gamma-subunit complex binding 2/1578 22/18639 0.0909090909090909 1.0737988247494 0.566694570953737 0.937165882464833 GO:0032931 histone H3K56 acetyltransferase activity 2/1578 22/18639 0.0909090909090909 1.0737988247494 0.566694570953737 0.937165882464833 GO:0043992 histone H3K9 acetyltransferase activity 2/1578 22/18639 0.0909090909090909 1.0737988247494 0.566694570953737 0.937165882464833 GO:0043993 histone H3K18 acetyltransferase activity 2/1578 22/18639 0.0909090909090909 1.0737988247494 0.566694570953737 0.937165882464833 GO:0043994 histone H3K23 acetyltransferase activity 2/1578 22/18639 0.0909090909090909 1.0737988247494 0.566694570953737 0.937165882464833 GO:0043999 histone H2AK5 acetyltransferase activity 2/1578 22/18639 0.0909090909090909 1.0737988247494 0.566694570953737 0.937165882464833 GO:0044012 histone H2AK9 acetyltransferase activity 2/1578 22/18639 0.0909090909090909 1.0737988247494 0.566694570953737 0.937165882464833 GO:0044014 histone H2BK5 acetyltransferase activity 2/1578 22/18639 0.0909090909090909 1.0737988247494 0.566694570953737 0.937165882464833 GO:0044015 histone H2BK12 acetyltransferase activity 2/1578 22/18639 0.0909090909090909 1.0737988247494 0.566694570953737 0.937165882464833 GO:0044016 histone H3K4 acetyltransferase activity 2/1578 22/18639 0.0909090909090909 1.0737988247494 0.566694570953737 0.937165882464833 GO:0044017 histone H3K27 acetyltransferase activity 2/1578 22/18639 0.0909090909090909 1.0737988247494 0.566694570953737 0.937165882464833 GO:0044018 histone H3K36 acetyltransferase activity 2/1578 22/18639 0.0909090909090909 1.0737988247494 0.566694570953737 0.937165882464833 GO:0046972 histone H4K16 acetyltransferase activity 2/1578 22/18639 0.0909090909090909 1.0737988247494 0.566694570953737 0.937165882464833 GO:0050321 tau-protein kinase activity 2/1578 22/18639 0.0909090909090909 1.0737988247494 0.566694570953737 0.937165882464833 GO:0070034 telomerase RNA binding 2/1578 22/18639 0.0909090909090909 1.0737988247494 0.566694570953737 0.937165882464833 GO:0140035 ubiquitin-like protein reader activity 2/1578 22/18639 0.0909090909090909 1.0737988247494 0.566694570953737 0.937165882464833 GO:0140908 histone H3K122 acetyltransferase activity 2/1578 22/18639 0.0909090909090909 1.0737988247494 0.566694570953737 0.937165882464833 GO:0005496 steroid binding 9/1578 108/18639 0.0833333333333333 0.984315589353612 0.570099740940429 0.937165882464833 GO:0010485 histone H4 acetyltransferase activity 3/1578 35/18639 0.0857142857142857 1.01243889190657 0.578383156531612 0.937165882464833 GO:0034061 DNA polymerase activity 3/1578 35/18639 0.0857142857142857 1.01243889190657 0.578383156531612 0.937165882464833 GO:0043015 gamma-tubulin binding 3/1578 35/18639 0.0857142857142857 1.01243889190657 0.578383156531612 0.937165882464833 GO:0061631 ubiquitin conjugating enzyme activity 3/1578 35/18639 0.0857142857142857 1.01243889190657 0.578383156531612 0.937165882464833 GO:0005539 glycosaminoglycan binding 20/1578 242/18639 0.0826446280991736 0.976180749772177 0.579049788840798 0.937165882464833 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 5/1578 60/18639 0.0833333333333333 0.984315589353612 0.581945526919463 0.937165882464833 GO:0000182 rDNA binding 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0001094 TFIID-class transcription factor complex binding 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0003796 lysozyme activity 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0004382 GDP phosphatase activity 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0004935 adrenergic receptor activity 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0004955 prostaglandin receptor activity 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0005031 tumor necrosis factor receptor activity 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0005345 purine nucleobase transmembrane transporter activity 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0005522 profilin binding 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0005528 FK506 binding 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0015279 store-operated calcium channel activity 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0015643 toxic substance binding 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0016175 superoxide-generating NAD(P)H oxidase activity 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0016783 sulfurtransferase activity 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0019911 structural constituent of myelin sheath 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0031419 cobalamin binding 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0031996 thioesterase binding 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0032356 oxidized DNA binding 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0032395 MHC class II receptor activity 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0043208 glycosphingolipid binding 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0050815 phosphoserine residue binding 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0051864 histone H3K36 demethylase activity 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0051880 G-quadruplex DNA binding 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0070739 protein-glutamic acid ligase activity 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0070740 tubulin-glutamic acid ligase activity 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0098505 G-rich strand telomeric DNA binding 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0099122 RNA polymerase II C-terminal domain binding 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0140940 histone H2A methyltransferase activity 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0141109 transporter activator activity 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:1990259 histone H2AQ104 methyltransferase activity 1/1578 10/18639 0.1 1.18117870722433 0.58721706648009 0.937165882464833 GO:0016879 ligase activity, forming carbon-nitrogen bonds 4/1578 48/18639 0.0833333333333333 0.984315589353612 0.588213897660421 0.937165882464833 GO:0000295 adenine nucleotide transmembrane transporter activity 2/1578 23/18639 0.0869565217391304 1.02711191932551 0.591314403832824 0.937165882464833 GO:0004022 alcohol dehydrogenase (NAD+) activity 2/1578 23/18639 0.0869565217391304 1.02711191932551 0.591314403832824 0.937165882464833 GO:0005158 insulin receptor binding 2/1578 23/18639 0.0869565217391304 1.02711191932551 0.591314403832824 0.937165882464833 GO:0042171 lysophosphatidic acid acyltransferase activity 2/1578 23/18639 0.0869565217391304 1.02711191932551 0.591314403832824 0.937165882464833 GO:0043274 phospholipase binding 2/1578 23/18639 0.0869565217391304 1.02711191932551 0.591314403832824 0.937165882464833 GO:0044013 histone H2B acetyltransferase activity 2/1578 23/18639 0.0869565217391304 1.02711191932551 0.591314403832824 0.937165882464833 GO:0071617 lysophospholipid acyltransferase activity 2/1578 23/18639 0.0869565217391304 1.02711191932551 0.591314403832824 0.937165882464833 GO:0099186 structural constituent of postsynapse 2/1578 23/18639 0.0869565217391304 1.02711191932551 0.591314403832824 0.937165882464833 GO:0140102 catalytic activity, acting on a rRNA 2/1578 23/18639 0.0869565217391304 1.02711191932551 0.591314403832824 0.937165882464833 GO:0004190 aspartic-type endopeptidase activity 3/1578 36/18639 0.0833333333333333 0.984315589353612 0.597889930072947 0.937165882464833 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/1578 36/18639 0.0833333333333333 0.984315589353612 0.597889930072947 0.937165882464833 GO:0016409 palmitoyltransferase activity 3/1578 36/18639 0.0833333333333333 0.984315589353612 0.597889930072947 0.937165882464833 GO:0008237 metallopeptidase activity 15/1578 184/18639 0.0815217391304348 0.962917424367664 0.599828076704782 0.937165882464833 GO:0016779 nucleotidyltransferase activity 11/1578 136/18639 0.0808823529411765 0.955365130843212 0.608068552887732 0.937165882464833 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 2/1578 24/18639 0.0833333333333333 0.984315589353612 0.61487430563277 0.937165882464833 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 2/1578 24/18639 0.0833333333333333 0.984315589353612 0.61487430563277 0.937165882464833 GO:0015149 hexose transmembrane transporter activity 2/1578 24/18639 0.0833333333333333 0.984315589353612 0.61487430563277 0.937165882464833 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 2/1578 24/18639 0.0833333333333333 0.984315589353612 0.61487430563277 0.937165882464833 GO:0030215 semaphorin receptor binding 2/1578 24/18639 0.0833333333333333 0.984315589353612 0.61487430563277 0.937165882464833 GO:0030552 cAMP binding 2/1578 24/18639 0.0833333333333333 0.984315589353612 0.61487430563277 0.937165882464833 GO:0043998 histone H2A acetyltransferase activity 2/1578 24/18639 0.0833333333333333 0.984315589353612 0.61487430563277 0.937165882464833 GO:0048027 mRNA 5'-UTR binding 2/1578 24/18639 0.0833333333333333 0.984315589353612 0.61487430563277 0.937165882464833 GO:0055056 D-glucose transmembrane transporter activity 2/1578 24/18639 0.0833333333333333 0.984315589353612 0.61487430563277 0.937165882464833 GO:0023023 MHC protein complex binding 3/1578 37/18639 0.0810810810810811 0.957712465317028 0.616795495960528 0.937165882464833 GO:0030551 cyclic nucleotide binding 3/1578 37/18639 0.0810810810810811 0.957712465317028 0.616795495960528 0.937165882464833 GO:0042805 actinin binding 3/1578 37/18639 0.0810810810810811 0.957712465317028 0.616795495960528 0.937165882464833 GO:0070001 aspartic-type peptidase activity 3/1578 37/18639 0.0810810810810811 0.957712465317028 0.616795495960528 0.937165882464833 GO:0000099 sulfur amino acid transmembrane transporter activity 1/1578 11/18639 0.0909090909090909 1.0737988247494 0.622182521904128 0.937165882464833 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/1578 11/18639 0.0909090909090909 1.0737988247494 0.622182521904128 0.937165882464833 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/1578 11/18639 0.0909090909090909 1.0737988247494 0.622182521904128 0.937165882464833 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 1/1578 11/18639 0.0909090909090909 1.0737988247494 0.622182521904128 0.937165882464833 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/1578 11/18639 0.0909090909090909 1.0737988247494 0.622182521904128 0.937165882464833 GO:0004954 prostanoid receptor activity 1/1578 11/18639 0.0909090909090909 1.0737988247494 0.622182521904128 0.937165882464833 GO:0008172 S-methyltransferase activity 1/1578 11/18639 0.0909090909090909 1.0737988247494 0.622182521904128 0.937165882464833 GO:0008199 ferric iron binding 1/1578 11/18639 0.0909090909090909 1.0737988247494 0.622182521904128 0.937165882464833 GO:0008503 benzodiazepine receptor activity 1/1578 11/18639 0.0909090909090909 1.0737988247494 0.622182521904128 0.937165882464833 GO:0015205 nucleobase transmembrane transporter activity 1/1578 11/18639 0.0909090909090909 1.0737988247494 0.622182521904128 0.937165882464833 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/1578 11/18639 0.0909090909090909 1.0737988247494 0.622182521904128 0.937165882464833 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/1578 11/18639 0.0909090909090909 1.0737988247494 0.622182521904128 0.937165882464833 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/1578 11/18639 0.0909090909090909 1.0737988247494 0.622182521904128 0.937165882464833 GO:0032404 mismatch repair complex binding 1/1578 11/18639 0.0909090909090909 1.0737988247494 0.622182521904128 0.937165882464833 GO:0035252 UDP-xylosyltransferase activity 1/1578 11/18639 0.0909090909090909 1.0737988247494 0.622182521904128 0.937165882464833 GO:0042285 xylosyltransferase activity 1/1578 11/18639 0.0909090909090909 1.0737988247494 0.622182521904128 0.937165882464833 GO:0042608 T cell receptor binding 1/1578 11/18639 0.0909090909090909 1.0737988247494 0.622182521904128 0.937165882464833 GO:0043522 leucine zipper domain binding 1/1578 11/18639 0.0909090909090909 1.0737988247494 0.622182521904128 0.937165882464833 GO:0045294 alpha-catenin binding 1/1578 11/18639 0.0909090909090909 1.0737988247494 0.622182521904128 0.937165882464833 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 1/1578 11/18639 0.0909090909090909 1.0737988247494 0.622182521904128 0.937165882464833 GO:0070697 activin receptor binding 1/1578 11/18639 0.0909090909090909 1.0737988247494 0.622182521904128 0.937165882464833 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/1578 11/18639 0.0909090909090909 1.0737988247494 0.622182521904128 0.937165882464833 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/1578 11/18639 0.0909090909090909 1.0737988247494 0.622182521904128 0.937165882464833 GO:0180030 inositol phosphate kinase activity 1/1578 11/18639 0.0909090909090909 1.0737988247494 0.622182521904128 0.937165882464833 GO:1990948 ubiquitin ligase inhibitor activity 1/1578 11/18639 0.0909090909090909 1.0737988247494 0.622182521904128 0.937165882464833 GO:0008234 cysteine-type peptidase activity 15/1578 187/18639 0.0802139037433155 0.947469551249466 0.625285359915325 0.937165882464833 GO:0017022 myosin binding 6/1578 76/18639 0.0789473684210526 0.932509505703422 0.63116431178836 0.937165882464833 GO:0016829 lyase activity 16/1578 200/18639 0.08 0.944942965779468 0.631211249673644 0.937165882464833 GO:0042162 telomeric DNA binding 3/1578 38/18639 0.0789473684210526 0.932509505703422 0.635089208777292 0.937165882464833 GO:0043531 ADP binding 3/1578 38/18639 0.0789473684210526 0.932509505703422 0.635089208777292 0.937165882464833 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 7/1578 89/18639 0.0786516853932584 0.929016960738241 0.636355391706789 0.937165882464833 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 7/1578 89/18639 0.0786516853932584 0.929016960738241 0.636355391706789 0.937165882464833 GO:0000030 mannosyltransferase activity 2/1578 25/18639 0.08 0.944942965779468 0.637377177329188 0.937165882464833 GO:0008483 transaminase activity 2/1578 25/18639 0.08 0.944942965779468 0.637377177329188 0.937165882464833 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 2/1578 25/18639 0.08 0.944942965779468 0.637377177329188 0.937165882464833 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 2/1578 25/18639 0.08 0.944942965779468 0.637377177329188 0.937165882464833 GO:0019211 phosphatase activator activity 2/1578 25/18639 0.08 0.944942965779468 0.637377177329188 0.937165882464833 GO:0019706 protein-cysteine S-palmitoyltransferase activity 2/1578 25/18639 0.08 0.944942965779468 0.637377177329188 0.937165882464833 GO:0019707 protein-cysteine S-acyltransferase activity 2/1578 25/18639 0.08 0.944942965779468 0.637377177329188 0.937165882464833 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 2/1578 25/18639 0.08 0.944942965779468 0.637377177329188 0.937165882464833 GO:0004536 DNA nuclease activity 5/1578 64/18639 0.078125 0.922795865019011 0.640026934729124 0.937165882464833 GO:1901681 sulfur compound binding 22/1578 275/18639 0.08 0.944942965779468 0.641871569299756 0.937165882464833 GO:0106310 protein serine kinase activity 29/1578 361/18639 0.0803324099722992 0.948869321592956 0.645047159910163 0.937165882464833 GO:0035401 histone H3Y41 kinase activity 9/1578 115/18639 0.0782608695652174 0.924400727392958 0.646470208314045 0.937165882464833 GO:0140801 histone H2AXY142 kinase activity 9/1578 115/18639 0.0782608695652174 0.924400727392958 0.646470208314045 0.937165882464833 GO:0140793 histone H2AXY142 phosphatase activity 7/1578 90/18639 0.0777777777777778 0.918694550063371 0.648111340431587 0.937165882464833 GO:0005080 protein kinase C binding 4/1578 52/18639 0.0769230769230769 0.908599005557181 0.652133047899326 0.937165882464833 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 39/1578 484/18639 0.0805785123966942 0.951776231027873 0.652218435360242 0.937165882464833 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 3/1578 39/18639 0.0769230769230769 0.908599005557181 0.652764203353289 0.937165882464833 GO:0000340 RNA 7-methylguanosine cap binding 1/1578 12/18639 0.0833333333333333 0.984315589353612 0.654187889116673 0.937165882464833 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/1578 12/18639 0.0833333333333333 0.984315589353612 0.654187889116673 0.937165882464833 GO:0004032 aldose reductase (NADPH) activity 1/1578 12/18639 0.0833333333333333 0.984315589353612 0.654187889116673 0.937165882464833 GO:0004300 enoyl-CoA hydratase activity 1/1578 12/18639 0.0833333333333333 0.984315589353612 0.654187889116673 0.937165882464833 GO:0004875 complement receptor activity 1/1578 12/18639 0.0833333333333333 0.984315589353612 0.654187889116673 0.937165882464833 GO:0005527 macrolide binding 1/1578 12/18639 0.0833333333333333 0.984315589353612 0.654187889116673 0.937165882464833 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/1578 12/18639 0.0833333333333333 0.984315589353612 0.654187889116673 0.937165882464833 GO:0008504 monoamine transmembrane transporter activity 1/1578 12/18639 0.0833333333333333 0.984315589353612 0.654187889116673 0.937165882464833 GO:0010853 cyclase activator activity 1/1578 12/18639 0.0833333333333333 0.984315589353612 0.654187889116673 0.937165882464833 GO:0015368 calcium:monoatomic cation antiporter activity 1/1578 12/18639 0.0833333333333333 0.984315589353612 0.654187889116673 0.937165882464833 GO:0016208 AMP binding 1/1578 12/18639 0.0833333333333333 0.984315589353612 0.654187889116673 0.937165882464833 GO:0016273 arginine N-methyltransferase activity 1/1578 12/18639 0.0833333333333333 0.984315589353612 0.654187889116673 0.937165882464833 GO:0016274 protein-arginine N-methyltransferase activity 1/1578 12/18639 0.0833333333333333 0.984315589353612 0.654187889116673 0.937165882464833 GO:0016423 tRNA (guanine) methyltransferase activity 1/1578 12/18639 0.0833333333333333 0.984315589353612 0.654187889116673 0.937165882464833 GO:0016801 hydrolase activity, acting on ether bonds 1/1578 12/18639 0.0833333333333333 0.984315589353612 0.654187889116673 0.937165882464833 GO:0016803 ether hydrolase activity 1/1578 12/18639 0.0833333333333333 0.984315589353612 0.654187889116673 0.937165882464833 GO:0035497 cAMP response element binding 1/1578 12/18639 0.0833333333333333 0.984315589353612 0.654187889116673 0.937165882464833 GO:0036009 protein-glutamine N-methyltransferase activity 1/1578 12/18639 0.0833333333333333 0.984315589353612 0.654187889116673 0.937165882464833 GO:0043047 single-stranded telomeric DNA binding 1/1578 12/18639 0.0833333333333333 0.984315589353612 0.654187889116673 0.937165882464833 GO:0045295 gamma-catenin binding 1/1578 12/18639 0.0833333333333333 0.984315589353612 0.654187889116673 0.937165882464833 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/1578 12/18639 0.0833333333333333 0.984315589353612 0.654187889116673 0.937165882464833 GO:0070410 co-SMAD binding 1/1578 12/18639 0.0833333333333333 0.984315589353612 0.654187889116673 0.937165882464833 GO:0097371 MDM2/MDM4 family protein binding 1/1578 12/18639 0.0833333333333333 0.984315589353612 0.654187889116673 0.937165882464833 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/1578 12/18639 0.0833333333333333 0.984315589353612 0.654187889116673 0.937165882464833 GO:1990459 transferrin receptor binding 1/1578 12/18639 0.0833333333333333 0.984315589353612 0.654187889116673 0.937165882464833 GO:0004529 DNA exonuclease activity 2/1578 26/18639 0.0769230769230769 0.908599005557181 0.658833021942313 0.938120933417859 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 2/1578 26/18639 0.0769230769230769 0.908599005557181 0.658833021942313 0.938120933417859 GO:0008143 poly(A) binding 2/1578 26/18639 0.0769230769230769 0.908599005557181 0.658833021942313 0.938120933417859 GO:0015145 monosaccharide transmembrane transporter activity 2/1578 26/18639 0.0769230769230769 0.908599005557181 0.658833021942313 0.938120933417859 GO:0052742 phosphatidylinositol kinase activity 2/1578 26/18639 0.0769230769230769 0.908599005557181 0.658833021942313 0.938120933417859 GO:0004864 protein phosphatase inhibitor activity 4/1578 53/18639 0.0754716981132075 0.891455628093837 0.667032257386769 0.94028842901273 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 3/1578 40/18639 0.075 0.885884030418251 0.669817028874355 0.94028842901273 GO:0032451 demethylase activity 3/1578 40/18639 0.075 0.885884030418251 0.669817028874355 0.94028842901273 GO:0050997 quaternary ammonium group binding 3/1578 40/18639 0.075 0.885884030418251 0.669817028874355 0.94028842901273 GO:0071855 neuropeptide receptor binding 3/1578 40/18639 0.075 0.885884030418251 0.669817028874355 0.94028842901273 GO:0140662 ATP-dependent protein folding chaperone 3/1578 40/18639 0.075 0.885884030418251 0.669817028874355 0.94028842901273 GO:0043178 alcohol binding 7/1578 92/18639 0.0760869565217391 0.89872292940982 0.670937479149338 0.94028842901273 GO:0052689 carboxylic ester hydrolase activity 7/1578 92/18639 0.0760869565217391 0.89872292940982 0.670937479149338 0.94028842901273 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 21/1578 268/18639 0.0783582089552239 0.925550479541456 0.677459037112485 0.94028842901273 GO:0004364 glutathione transferase activity 2/1578 27/18639 0.0740740740740741 0.874947190536544 0.679257722617152 0.94028842901273 GO:0004683 calcium/calmodulin-dependent protein kinase activity 2/1578 27/18639 0.0740740740740741 0.874947190536544 0.679257722617152 0.94028842901273 GO:0005104 fibroblast growth factor receptor binding 2/1578 27/18639 0.0740740740740741 0.874947190536544 0.679257722617152 0.94028842901273 GO:0008266 poly(U) RNA binding 2/1578 27/18639 0.0740740740740741 0.874947190536544 0.679257722617152 0.94028842901273 GO:0035255 ionotropic glutamate receptor binding 2/1578 27/18639 0.0740740740740741 0.874947190536544 0.679257722617152 0.94028842901273 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/1578 13/18639 0.0769230769230769 0.908599005557181 0.683483616339194 0.94028842901273 GO:0004535 poly(A)-specific ribonuclease activity 1/1578 13/18639 0.0769230769230769 0.908599005557181 0.683483616339194 0.94028842901273 GO:0005035 death receptor activity 1/1578 13/18639 0.0769230769230769 0.908599005557181 0.683483616339194 0.94028842901273 GO:0005172 vascular endothelial growth factor receptor binding 1/1578 13/18639 0.0769230769230769 0.908599005557181 0.683483616339194 0.94028842901273 GO:0005542 folic acid binding 1/1578 13/18639 0.0769230769230769 0.908599005557181 0.683483616339194 0.94028842901273 GO:0008253 5'-nucleotidase activity 1/1578 13/18639 0.0769230769230769 0.908599005557181 0.683483616339194 0.94028842901273 GO:0009982 pseudouridine synthase activity 1/1578 13/18639 0.0769230769230769 0.908599005557181 0.683483616339194 0.94028842901273 GO:0019104 DNA N-glycosylase activity 1/1578 13/18639 0.0769230769230769 0.908599005557181 0.683483616339194 0.94028842901273 GO:0019855 calcium channel inhibitor activity 1/1578 13/18639 0.0769230769230769 0.908599005557181 0.683483616339194 0.94028842901273 GO:0031432 titin binding 1/1578 13/18639 0.0769230769230769 0.908599005557181 0.683483616339194 0.94028842901273 GO:0031994 insulin-like growth factor I binding 1/1578 13/18639 0.0769230769230769 0.908599005557181 0.683483616339194 0.94028842901273 GO:0039706 co-receptor binding 1/1578 13/18639 0.0769230769230769 0.908599005557181 0.683483616339194 0.94028842901273 GO:0045159 myosin II binding 1/1578 13/18639 0.0769230769230769 0.908599005557181 0.683483616339194 0.94028842901273 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/1578 13/18639 0.0769230769230769 0.908599005557181 0.683483616339194 0.94028842901273 GO:0061459 L-arginine transmembrane transporter activity 1/1578 13/18639 0.0769230769230769 0.908599005557181 0.683483616339194 0.94028842901273 GO:0001727 lipid kinase activity 3/1578 41/18639 0.0731707317073171 0.864277102847074 0.686247301111438 0.940797172105099 GO:0016877 ligase activity, forming carbon-sulfur bonds 3/1578 41/18639 0.0731707317073171 0.864277102847074 0.686247301111438 0.940797172105099 GO:0042287 MHC protein binding 3/1578 41/18639 0.0731707317073171 0.864277102847074 0.686247301111438 0.940797172105099 GO:0001216 DNA-binding transcription activator activity 39/1578 491/18639 0.0794297352342159 0.938207119791223 0.687172880136006 0.940971922973695 GO:0003779 actin binding 35/1578 443/18639 0.0790067720090293 0.93321116823593 0.692222223330421 0.941726478621343 GO:0098632 cell-cell adhesion mediator activity 4/1578 55/18639 0.0727272727272727 0.859039059799516 0.695497655701272 0.941726478621343 GO:0005096 GTPase activator activity 21/1578 271/18639 0.0774907749077491 0.91530453327347 0.696923343123072 0.941726478621343 GO:0045499 chemorepellent activity 2/1578 28/18639 0.0714285714285714 0.84369907658881 0.698671976487291 0.941726478621343 GO:0051119 sugar transmembrane transporter activity 2/1578 28/18639 0.0714285714285714 0.84369907658881 0.698671976487291 0.941726478621343 GO:0051393 alpha-actinin binding 2/1578 28/18639 0.0714285714285714 0.84369907658881 0.698671976487291 0.941726478621343 GO:0004520 DNA endonuclease activity 3/1578 42/18639 0.0714285714285714 0.84369907658881 0.702057373735687 0.941726478621343 GO:0008307 structural constituent of muscle 3/1578 42/18639 0.0714285714285714 0.84369907658881 0.702057373735687 0.941726478621343 GO:0048487 beta-tubulin binding 3/1578 42/18639 0.0714285714285714 0.84369907658881 0.702057373735687 0.941726478621343 GO:0008276 protein methyltransferase activity 7/1578 95/18639 0.0736842105263158 0.870342205323194 0.703403808939342 0.941726478621343 GO:0019212 phosphatase inhibitor activity 4/1578 56/18639 0.0714285714285714 0.84369907658881 0.709060596264517 0.941726478621343 GO:0004705 JUN kinase activity 1/1578 14/18639 0.0714285714285714 0.84369907658881 0.710298974087328 0.941726478621343 GO:0005545 1-phosphatidylinositol binding 1/1578 14/18639 0.0714285714285714 0.84369907658881 0.710298974087328 0.941726478621343 GO:0008195 phosphatidate phosphatase activity 1/1578 14/18639 0.0714285714285714 0.84369907658881 0.710298974087328 0.941726478621343 GO:0008559 ABC-type xenobiotic transporter activity 1/1578 14/18639 0.0714285714285714 0.84369907658881 0.710298974087328 0.941726478621343 GO:0019992 diacylglycerol binding 1/1578 14/18639 0.0714285714285714 0.84369907658881 0.710298974087328 0.941726478621343 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/1578 14/18639 0.0714285714285714 0.84369907658881 0.710298974087328 0.941726478621343 GO:0031404 chloride ion binding 1/1578 14/18639 0.0714285714285714 0.84369907658881 0.710298974087328 0.941726478621343 GO:0032036 myosin heavy chain binding 1/1578 14/18639 0.0714285714285714 0.84369907658881 0.710298974087328 0.941726478621343 GO:0042043 neurexin family protein binding 1/1578 14/18639 0.0714285714285714 0.84369907658881 0.710298974087328 0.941726478621343 GO:0043176 amine binding 1/1578 14/18639 0.0714285714285714 0.84369907658881 0.710298974087328 0.941726478621343 GO:0061783 peptidoglycan muralytic activity 1/1578 14/18639 0.0714285714285714 0.84369907658881 0.710298974087328 0.941726478621343 GO:0070742 C2H2 zinc finger domain binding 1/1578 14/18639 0.0714285714285714 0.84369907658881 0.710298974087328 0.941726478621343 GO:0071933 Arp2/3 complex binding 1/1578 14/18639 0.0714285714285714 0.84369907658881 0.710298974087328 0.941726478621343 GO:1901474 azole transmembrane transporter activity 1/1578 14/18639 0.0714285714285714 0.84369907658881 0.710298974087328 0.941726478621343 GO:1990825 sequence-specific mRNA binding 1/1578 14/18639 0.0714285714285714 0.84369907658881 0.710298974087328 0.941726478621343 GO:0030165 PDZ domain binding 6/1578 83/18639 0.072289156626506 0.853864125704338 0.714658890286775 0.941726478621343 GO:0004629 phospholipase C activity 2/1578 29/18639 0.0689655172413793 0.8146060049823 0.717100366728386 0.941726478621343 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 2/1578 29/18639 0.0689655172413793 0.8146060049823 0.717100366728386 0.941726478621343 GO:0016417 S-acyltransferase activity 2/1578 29/18639 0.0689655172413793 0.8146060049823 0.717100366728386 0.941726478621343 GO:0097472 cyclin-dependent protein kinase activity 2/1578 29/18639 0.0689655172413793 0.8146060049823 0.717100366728386 0.941726478621343 GO:0099604 ligand-gated calcium channel activity 2/1578 29/18639 0.0689655172413793 0.8146060049823 0.717100366728386 0.941726478621343 GO:0004712 protein serine/threonine/tyrosine kinase activity 3/1578 43/18639 0.0697674418604651 0.824078167830931 0.717252029272628 0.941726478621343 GO:0004222 metalloendopeptidase activity 8/1578 110/18639 0.0727272727272727 0.859039059799516 0.723334661044024 0.941726478621343 GO:0031406 carboxylic acid binding 14/1578 187/18639 0.0748663101604278 0.884304914499502 0.723336019984083 0.941726478621343 GO:0019842 vitamin binding 11/1578 150/18639 0.0733333333333333 0.866197718631179 0.733585736569972 0.941726478621343 GO:0004725 protein tyrosine phosphatase activity 7/1578 98/18639 0.0714285714285714 0.84369907658881 0.73368182599364 0.941726478621343 GO:0001968 fibronectin binding 2/1578 30/18639 0.0666666666666667 0.78745247148289 0.734570557066984 0.941726478621343 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 2/1578 30/18639 0.0666666666666667 0.78745247148289 0.734570557066984 0.941726478621343 GO:0008106 alcohol dehydrogenase (NADP+) activity 2/1578 30/18639 0.0666666666666667 0.78745247148289 0.734570557066984 0.941726478621343 GO:0008187 poly-pyrimidine tract binding 2/1578 30/18639 0.0666666666666667 0.78745247148289 0.734570557066984 0.941726478621343 GO:0016769 transferase activity, transferring nitrogenous groups 2/1578 30/18639 0.0666666666666667 0.78745247148289 0.734570557066984 0.941726478621343 GO:0031210 phosphatidylcholine binding 2/1578 30/18639 0.0666666666666667 0.78745247148289 0.734570557066984 0.941726478621343 GO:0032452 histone demethylase activity 2/1578 30/18639 0.0666666666666667 0.78745247148289 0.734570557066984 0.941726478621343 GO:0098918 structural constituent of synapse 2/1578 30/18639 0.0666666666666667 0.78745247148289 0.734570557066984 0.941726478621343 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/1578 15/18639 0.0666666666666667 0.78745247148289 0.734843844900225 0.941726478621343 GO:0004953 icosanoid receptor activity 1/1578 15/18639 0.0666666666666667 0.78745247148289 0.734843844900225 0.941726478621343 GO:0008252 nucleotidase activity 1/1578 15/18639 0.0666666666666667 0.78745247148289 0.734843844900225 0.941726478621343 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 1/1578 15/18639 0.0666666666666667 0.78745247148289 0.734843844900225 0.941726478621343 GO:0031386 protein tag activity 1/1578 15/18639 0.0666666666666667 0.78745247148289 0.734843844900225 0.941726478621343 GO:0034483 heparan sulfate sulfotransferase activity 1/1578 15/18639 0.0666666666666667 0.78745247148289 0.734843844900225 0.941726478621343 GO:0051371 muscle alpha-actinin binding 1/1578 15/18639 0.0666666666666667 0.78745247148289 0.734843844900225 0.941726478621343 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/1578 15/18639 0.0666666666666667 0.78745247148289 0.734843844900225 0.941726478621343 GO:0061578 K63-linked deubiquitinase activity 1/1578 15/18639 0.0666666666666667 0.78745247148289 0.734843844900225 0.941726478621343 GO:0140776 protein-containing complex destabilizing activity 1/1578 15/18639 0.0666666666666667 0.78745247148289 0.734843844900225 0.941726478621343 GO:0141047 molecular tag activity 1/1578 15/18639 0.0666666666666667 0.78745247148289 0.734843844900225 0.941726478621343 GO:0141050 histone H3K deacetylase activity 1/1578 15/18639 0.0666666666666667 0.78745247148289 0.734843844900225 0.941726478621343 GO:0141051 histone H4K deacetylase activity 1/1578 15/18639 0.0666666666666667 0.78745247148289 0.734843844900225 0.941726478621343 GO:0017116 single-stranded DNA helicase activity 4/1578 58/18639 0.0689655172413793 0.8146060049823 0.734850178398333 0.941726478621343 GO:0043177 organic acid binding 14/1578 189/18639 0.0740740740740741 0.874947190536544 0.737655782489923 0.944295513089706 GO:0001217 DNA-binding transcription repressor activity 21/1578 278/18639 0.0755395683453237 0.892257296824138 0.739642923583598 0.945309654856561 GO:0042379 chemokine receptor binding 5/1578 72/18639 0.0694444444444444 0.82026299112801 0.740051578823245 0.945309654856561 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 6/1578 86/18639 0.0697674418604651 0.824078167830931 0.74616453088273 0.951246038064515 GO:0016411 acylglycerol O-acyltransferase activity 2/1578 31/18639 0.0645161290322581 0.762050778854409 0.751112594681562 0.951246038064515 GO:0017147 Wnt-protein binding 2/1578 31/18639 0.0645161290322581 0.762050778854409 0.751112594681562 0.951246038064515 GO:0047499 calcium-independent phospholipase A2 activity 2/1578 31/18639 0.0645161290322581 0.762050778854409 0.751112594681562 0.951246038064515 GO:0072349 modified amino acid transmembrane transporter activity 2/1578 31/18639 0.0645161290322581 0.762050778854409 0.751112594681562 0.951246038064515 GO:0140457 protein demethylase activity 2/1578 31/18639 0.0645161290322581 0.762050778854409 0.751112594681562 0.951246038064515 GO:0004707 MAP kinase activity 1/1578 16/18639 0.0625 0.738236692015209 0.757310361907712 0.951246038064515 GO:0005149 interleukin-1 receptor binding 1/1578 16/18639 0.0625 0.738236692015209 0.757310361907712 0.951246038064515 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/1578 16/18639 0.0625 0.738236692015209 0.757310361907712 0.951246038064515 GO:0022841 potassium ion leak channel activity 1/1578 16/18639 0.0625 0.738236692015209 0.757310361907712 0.951246038064515 GO:0022858 alanine transmembrane transporter activity 1/1578 16/18639 0.0625 0.738236692015209 0.757310361907712 0.951246038064515 GO:0030275 LRR domain binding 1/1578 16/18639 0.0625 0.738236692015209 0.757310361907712 0.951246038064515 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1/1578 16/18639 0.0625 0.738236692015209 0.757310361907712 0.951246038064515 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/1578 16/18639 0.0625 0.738236692015209 0.757310361907712 0.951246038064515 GO:0019783 ubiquitin-like protein peptidase activity 9/1578 127/18639 0.0708661417322835 0.837055776773151 0.757675461987015 0.951246038064515 GO:0140996 histone H3 kinase activity 27/1578 357/18639 0.0756302521008403 0.893328434035211 0.758763269795173 0.951246038064515 GO:0004180 carboxypeptidase activity 3/1578 46/18639 0.0652173913043478 0.770333939494131 0.759221816640126 0.951246038064515 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 3/1578 46/18639 0.0652173913043478 0.770333939494131 0.759221816640126 0.951246038064515 GO:0003678 DNA helicase activity 5/1578 74/18639 0.0675675675675676 0.798093721097523 0.761574888314712 0.953181309260133 GO:0005506 iron ion binding 11/1578 154/18639 0.0714285714285714 0.84369907658881 0.76406340727238 0.955281820969391 GO:0030515 snoRNA binding 2/1578 32/18639 0.0625 0.738236692015209 0.766758308933848 0.955611042529606 GO:0042910 xenobiotic transmembrane transporter activity 2/1578 32/18639 0.0625 0.738236692015209 0.766758308933848 0.955611042529606 GO:0047498 calcium-dependent phospholipase A2 activity 2/1578 32/18639 0.0625 0.738236692015209 0.766758308933848 0.955611042529606 GO:0019003 GDP binding 5/1578 75/18639 0.0666666666666667 0.78745247148289 0.771820049962928 0.958144132621914 GO:0043495 protein-membrane adaptor activity 3/1578 47/18639 0.0638297872340425 0.753943855675107 0.772041497871771 0.958144132621914 GO:0061749 forked DNA-dependent helicase activity 3/1578 47/18639 0.0638297872340425 0.753943855675107 0.772041497871771 0.958144132621914 GO:1990518 single-stranded 3'-5' DNA helicase activity 3/1578 47/18639 0.0638297872340425 0.753943855675107 0.772041497871771 0.958144132621914 GO:0035173 histone kinase activity 27/1578 360/18639 0.075 0.885884030418251 0.77332361906018 0.958321764059874 GO:0030414 peptidase inhibitor activity 12/1578 169/18639 0.0710059171597633 0.838706774360474 0.77776162641935 0.958321764059874 GO:0004550 nucleoside diphosphate kinase activity 1/1578 17/18639 0.0588235294117647 0.694811004249609 0.777874408995165 0.958321764059874 GO:0008429 phosphatidylethanolamine binding 1/1578 17/18639 0.0588235294117647 0.694811004249609 0.777874408995165 0.958321764059874 GO:0016805 dipeptidase activity 1/1578 17/18639 0.0588235294117647 0.694811004249609 0.777874408995165 0.958321764059874 GO:0031489 myosin V binding 1/1578 17/18639 0.0588235294117647 0.694811004249609 0.777874408995165 0.958321764059874 GO:0070492 oligosaccharide binding 1/1578 17/18639 0.0588235294117647 0.694811004249609 0.777874408995165 0.958321764059874 GO:0035402 histone H3T11 kinase activity 18/1578 247/18639 0.0728744939271255 0.860778005264697 0.780283501271735 0.959057468582988 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2/1578 33/18639 0.0606060606060606 0.715865883166263 0.781540794716656 0.959057468582988 GO:0030296 protein tyrosine kinase activator activity 2/1578 33/18639 0.0606060606060606 0.715865883166263 0.781540794716656 0.959057468582988 GO:0098631 cell adhesion mediator activity 5/1578 76/18639 0.0657894736842105 0.777091254752852 0.781725383637194 0.959057468582988 GO:0009378 four-way junction helicase activity 3/1578 48/18639 0.0625 0.738236692015209 0.784296671219194 0.959058864822413 GO:0036121 double-stranded DNA helicase activity 3/1578 48/18639 0.0625 0.738236692015209 0.784296671219194 0.959058864822413 GO:0043138 3'-5' DNA helicase activity 3/1578 48/18639 0.0625 0.738236692015209 0.784296671219194 0.959058864822413 GO:1901682 sulfur compound transmembrane transporter activity 4/1578 63/18639 0.0634920634920635 0.749954734745609 0.791703307494875 0.959058864822413 GO:0030332 cyclin binding 2/1578 34/18639 0.0588235294117647 0.694811004249609 0.795493970414482 0.959058864822413 GO:0051427 hormone receptor binding 2/1578 34/18639 0.0588235294117647 0.694811004249609 0.795493970414482 0.959058864822413 GO:0090482 vitamin transmembrane transporter activity 2/1578 34/18639 0.0588235294117647 0.694811004249609 0.795493970414482 0.959058864822413 GO:0016854 racemase and epimerase activity 1/1578 18/18639 0.0555555555555556 0.656210392902408 0.796696994249468 0.959058864822413 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/1578 18/18639 0.0555555555555556 0.656210392902408 0.796696994249468 0.959058864822413 GO:0034185 apolipoprotein binding 1/1578 18/18639 0.0555555555555556 0.656210392902408 0.796696994249468 0.959058864822413 GO:0050811 GABA receptor binding 1/1578 18/18639 0.0555555555555556 0.656210392902408 0.796696994249468 0.959058864822413 GO:1901611 phosphatidylglycerol binding 1/1578 18/18639 0.0555555555555556 0.656210392902408 0.796696994249468 0.959058864822413 GO:0141003 histone H2AX kinase activity 26/1578 354/18639 0.0734463276836158 0.867532383837082 0.803837974238308 0.959058864822413 GO:0048020 CCR chemokine receptor binding 3/1578 50/18639 0.06 0.708707224334601 0.807170146431925 0.959058864822413 GO:0004623 phospholipase A2 activity 2/1578 35/18639 0.0571428571428571 0.674959261271048 0.808652201558898 0.959058864822413 GO:0004866 endopeptidase inhibitor activity 11/1578 161/18639 0.0683229813664596 0.807016508041471 0.811389529071069 0.959058864822413 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/1578 19/18639 0.0526315789473684 0.621673003802281 0.813925507383797 0.959058864822413 GO:0005520 insulin-like growth factor binding 1/1578 19/18639 0.0526315789473684 0.621673003802281 0.813925507383797 0.959058864822413 GO:0008301 DNA binding, bending 1/1578 19/18639 0.0526315789473684 0.621673003802281 0.813925507383797 0.959058864822413 GO:0008381 mechanosensitive monoatomic ion channel activity 1/1578 19/18639 0.0526315789473684 0.621673003802281 0.813925507383797 0.959058864822413 GO:0022840 leak channel activity 1/1578 19/18639 0.0526315789473684 0.621673003802281 0.813925507383797 0.959058864822413 GO:0022842 narrow pore channel activity 1/1578 19/18639 0.0526315789473684 0.621673003802281 0.813925507383797 0.959058864822413 GO:0030506 ankyrin binding 1/1578 19/18639 0.0526315789473684 0.621673003802281 0.813925507383797 0.959058864822413 GO:0043395 heparan sulfate proteoglycan binding 1/1578 19/18639 0.0526315789473684 0.621673003802281 0.813925507383797 0.959058864822413 GO:0070003 threonine-type peptidase activity 1/1578 19/18639 0.0526315789473684 0.621673003802281 0.813925507383797 0.959058864822413 GO:0015297 antiporter activity 9/1578 135/18639 0.0666666666666667 0.78745247148289 0.816712649840388 0.959058864822413 GO:0008235 metalloexopeptidase activity 4/1578 66/18639 0.0606060606060606 0.715865883166263 0.820842384828032 0.959058864822413 GO:0004033 aldo-keto reductase (NADPH) activity 2/1578 36/18639 0.0555555555555556 0.656210392902408 0.821049982234542 0.959058864822413 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 16/1578 229/18639 0.0698689956331878 0.825277699370714 0.822527815640994 0.959058864822413 GO:0004867 serine-type endopeptidase inhibitor activity 6/1578 95/18639 0.0631578947368421 0.746007604562738 0.825356044658618 0.959058864822413 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 17/1578 243/18639 0.0699588477366255 0.826339013284514 0.826994183139674 0.959058864822413 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 3/1578 52/18639 0.0576923076923077 0.681449254167885 0.827962639482251 0.959058864822413 GO:0000339 RNA cap binding 1/1578 20/18639 0.05 0.590589353612167 0.829694870936341 0.959058864822413 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/1578 20/18639 0.05 0.590589353612167 0.829694870936341 0.959058864822413 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/1578 20/18639 0.05 0.590589353612167 0.829694870936341 0.959058864822413 GO:0005326 neurotransmitter transmembrane transporter activity 1/1578 20/18639 0.05 0.590589353612167 0.829694870936341 0.959058864822413 GO:0015095 magnesium ion transmembrane transporter activity 1/1578 20/18639 0.05 0.590589353612167 0.829694870936341 0.959058864822413 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/1578 20/18639 0.05 0.590589353612167 0.829694870936341 0.959058864822413 GO:0030627 pre-mRNA 5'-splice site binding 1/1578 20/18639 0.05 0.590589353612167 0.829694870936341 0.959058864822413 GO:0030742 GTP-dependent protein binding 1/1578 20/18639 0.05 0.590589353612167 0.829694870936341 0.959058864822413 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 4/1578 67/18639 0.0597014925373134 0.705181317745871 0.829776104230491 0.959058864822413 GO:0005319 lipid transporter activity 12/1578 178/18639 0.0674157303370786 0.796300252061349 0.832700561868959 0.959058864822413 GO:0030280 structural constituent of skin epidermis 2/1578 37/18639 0.0540540540540541 0.638474976878019 0.832721667164486 0.959058864822413 GO:0016407 acetyltransferase activity 6/1578 96/18639 0.0625 0.738236692015209 0.832796989958544 0.959058864822413 GO:0004676 3-phosphoinositide-dependent protein kinase activity 17/1578 245/18639 0.0693877551020408 0.819593388686273 0.836467698760462 0.959058864822413 GO:0004711 ribosomal protein S6 kinase activity 17/1578 245/18639 0.0693877551020408 0.819593388686273 0.836467698760462 0.959058864822413 GO:0035175 histone H3S10 kinase activity 17/1578 245/18639 0.0693877551020408 0.819593388686273 0.836467698760462 0.959058864822413 GO:0035979 histone H2AXS139 kinase activity 17/1578 245/18639 0.0693877551020408 0.819593388686273 0.836467698760462 0.959058864822413 GO:0044022 histone H3S28 kinase activity 17/1578 245/18639 0.0693877551020408 0.819593388686273 0.836467698760462 0.959058864822413 GO:0044023 histone H4S1 kinase activity 17/1578 245/18639 0.0693877551020408 0.819593388686273 0.836467698760462 0.959058864822413 GO:0044024 histone H2AS1 kinase activity 17/1578 245/18639 0.0693877551020408 0.819593388686273 0.836467698760462 0.959058864822413 GO:0044025 histone H2BS14 kinase activity 17/1578 245/18639 0.0693877551020408 0.819593388686273 0.836467698760462 0.959058864822413 GO:0072354 histone H3T3 kinase activity 17/1578 245/18639 0.0693877551020408 0.819593388686273 0.836467698760462 0.959058864822413 GO:0072371 histone H2AS121 kinase activity 17/1578 245/18639 0.0693877551020408 0.819593388686273 0.836467698760462 0.959058864822413 GO:0072518 Rho-dependent protein serine/threonine kinase activity 17/1578 245/18639 0.0693877551020408 0.819593388686273 0.836467698760462 0.959058864822413 GO:0140823 histone H2BS36 kinase activity 17/1578 245/18639 0.0693877551020408 0.819593388686273 0.836467698760462 0.959058864822413 GO:0140855 histone H3S57 kinase activity 17/1578 245/18639 0.0693877551020408 0.819593388686273 0.836467698760462 0.959058864822413 GO:0140995 histone H2A kinase activity 17/1578 245/18639 0.0693877551020408 0.819593388686273 0.836467698760462 0.959058864822413 GO:0140997 histone H4 kinase activity 17/1578 245/18639 0.0693877551020408 0.819593388686273 0.836467698760462 0.959058864822413 GO:0140998 histone H2B kinase activity 17/1578 245/18639 0.0693877551020408 0.819593388686273 0.836467698760462 0.959058864822413 GO:1990244 histone H2AT120 kinase activity 17/1578 245/18639 0.0693877551020408 0.819593388686273 0.836467698760462 0.959058864822413 GO:0005246 calcium channel regulator activity 3/1578 53/18639 0.0566037735849057 0.668591721070378 0.837618462407981 0.959058864822413 GO:0005544 calcium-dependent phospholipid binding 3/1578 53/18639 0.0566037735849057 0.668591721070378 0.837618462407981 0.959058864822413 GO:0017046 peptide hormone binding 3/1578 53/18639 0.0566037735849057 0.668591721070378 0.837618462407981 0.959058864822413 GO:0032934 sterol binding 4/1578 68/18639 0.0588235294117647 0.694811004249609 0.838335956832022 0.959058864822413 GO:0004677 DNA-dependent protein kinase activity 17/1578 246/18639 0.0691056910569106 0.816261708244459 0.841056980985779 0.959058864822413 GO:0140857 histone H3T45 kinase activity 17/1578 246/18639 0.0691056910569106 0.816261708244459 0.841056980985779 0.959058864822413 GO:0140101 catalytic activity, acting on a tRNA 9/1578 139/18639 0.0647482014388489 0.764791968706404 0.841807383488668 0.959058864822413 GO:0140767 enzyme-substrate adaptor activity 9/1578 139/18639 0.0647482014388489 0.764791968706404 0.841807383488668 0.959058864822413 GO:0042887 amide transmembrane transporter activity 2/1578 38/18639 0.0526315789473684 0.621673003802281 0.843701248185997 0.959058864822413 GO:0005248 voltage-gated sodium channel activity 1/1578 21/18639 0.0476190476190476 0.562466051059207 0.844128594211621 0.959058864822413 GO:0015174 basic amino acid transmembrane transporter activity 1/1578 21/18639 0.0476190476190476 0.562466051059207 0.844128594211621 0.959058864822413 GO:0019200 carbohydrate kinase activity 1/1578 21/18639 0.0476190476190476 0.562466051059207 0.844128594211621 0.959058864822413 GO:0036122 BMP binding 1/1578 21/18639 0.0476190476190476 0.562466051059207 0.844128594211621 0.959058864822413 GO:0051428 peptide hormone receptor binding 1/1578 21/18639 0.0476190476190476 0.562466051059207 0.844128594211621 0.959058864822413 GO:0070182 DNA polymerase binding 1/1578 21/18639 0.0476190476190476 0.562466051059207 0.844128594211621 0.959058864822413 GO:0035403 histone H3T6 kinase activity 17/1578 247/18639 0.0688259109311741 0.812957004972214 0.845548933834209 0.959058864822413 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 11/1578 167/18639 0.0658682634730539 0.778021902962137 0.846016873502826 0.959058864822413 GO:0016279 protein-lysine N-methyltransferase activity 4/1578 69/18639 0.0579710144927536 0.684741279550339 0.846531897895996 0.959058864822413 GO:0015485 cholesterol binding 3/1578 54/18639 0.0555555555555556 0.656210392902408 0.846802610924624 0.959058864822413 GO:0004679 AMP-activated protein kinase activity 17/1578 248/18639 0.0685483870967742 0.80967895253281 0.849944361364059 0.960839877670948 GO:0004175 endopeptidase activity 29/1578 405/18639 0.0716049382716049 0.845782284185326 0.852630073011322 0.960839877670948 GO:0016278 lysine N-methyltransferase activity 4/1578 70/18639 0.0571428571428571 0.674959261271048 0.854374113907736 0.960839877670948 GO:0004407 histone deacetylase activity 1/1578 22/18639 0.0454545454545455 0.536899412374698 0.857339738176283 0.960839877670948 GO:0008093 cytoskeletal anchor activity 1/1578 22/18639 0.0454545454545455 0.536899412374698 0.857339738176283 0.960839877670948 GO:0008649 rRNA methyltransferase activity 1/1578 22/18639 0.0454545454545455 0.536899412374698 0.857339738176283 0.960839877670948 GO:0008970 phospholipase A1 activity 1/1578 22/18639 0.0454545454545455 0.536899412374698 0.857339738176283 0.960839877670948 GO:0015377 chloride:monoatomic cation symporter activity 1/1578 22/18639 0.0454545454545455 0.536899412374698 0.857339738176283 0.960839877670948 GO:0033558 protein lysine deacetylase activity 1/1578 22/18639 0.0454545454545455 0.536899412374698 0.857339738176283 0.960839877670948 GO:0034062 5'-3' RNA polymerase activity 1/1578 22/18639 0.0454545454545455 0.536899412374698 0.857339738176283 0.960839877670948 GO:0097747 RNA polymerase activity 1/1578 22/18639 0.0454545454545455 0.536899412374698 0.857339738176283 0.960839877670948 GO:0015144 carbohydrate transmembrane transporter activity 2/1578 40/18639 0.05 0.590589353612167 0.863717176931145 0.967004373955595 GO:0101005 deubiquitinase activity 7/1578 115/18639 0.0608695652173913 0.718978343527856 0.864480585368275 0.967004373955595 GO:0004602 glutathione peroxidase activity 1/1578 23/18639 0.0434782608695652 0.513555959662754 0.869431798828258 0.96795098283146 GO:0005212 structural constituent of eye lens 1/1578 23/18639 0.0434782608695652 0.513555959662754 0.869431798828258 0.96795098283146 GO:0016493 C-C chemokine receptor activity 1/1578 23/18639 0.0434782608695652 0.513555959662754 0.869431798828258 0.96795098283146 GO:0017134 fibroblast growth factor binding 1/1578 23/18639 0.0434782608695652 0.513555959662754 0.869431798828258 0.96795098283146 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/1578 23/18639 0.0434782608695652 0.513555959662754 0.869431798828258 0.96795098283146 GO:0015171 amino acid transmembrane transporter activity 6/1578 102/18639 0.0588235294117647 0.694811004249609 0.872230687223537 0.968976133073877 GO:0015175 neutral L-amino acid transmembrane transporter activity 2/1578 41/18639 0.0487804878048781 0.576184735231383 0.872818196203951 0.968976133073877 GO:0140828 metal cation:monoatomic cation antiporter activity 2/1578 41/18639 0.0487804878048781 0.576184735231383 0.872818196203951 0.968976133073877 GO:0016741 transferase activity, transferring one-carbon groups 14/1578 215/18639 0.0651162790697674 0.769139623308869 0.87971877295708 0.975666286911709 GO:0019957 C-C chemokine binding 1/1578 24/18639 0.0416666666666667 0.492157794676806 0.880499515923714 0.975666286911709 GO:0001786 phosphatidylserine binding 3/1578 59/18639 0.0508474576271186 0.600599342656441 0.886231199478251 0.981095384211134 GO:0008083 growth factor activity 10/1578 162/18639 0.0617283950617284 0.729122658780453 0.888156758267392 0.98227531726615 GO:0005537 D-mannose binding 1/1578 25/18639 0.04 0.472471482889734 0.890629613365152 0.98227531726615 GO:0015271 outward rectifier potassium channel activity 1/1578 25/18639 0.04 0.472471482889734 0.890629613365152 0.98227531726615 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/1578 25/18639 0.04 0.472471482889734 0.890629613365152 0.98227531726615 GO:0000149 SNARE binding 6/1578 106/18639 0.0566037735849057 0.668591721070378 0.893949941264656 0.985015869860775 GO:0016836 hydro-lyase activity 3/1578 61/18639 0.0491803278688525 0.580907560930001 0.899280163212644 0.986044462276037 GO:0001637 G protein-coupled chemoattractant receptor activity 1/1578 26/18639 0.0384615384615385 0.45429950277859 0.899901477022066 0.986044462276037 GO:0004435 phosphatidylinositol phospholipase C activity 1/1578 26/18639 0.0384615384615385 0.45429950277859 0.899901477022066 0.986044462276037 GO:0004950 chemokine receptor activity 1/1578 26/18639 0.0384615384615385 0.45429950277859 0.899901477022066 0.986044462276037 GO:0005112 Notch binding 1/1578 26/18639 0.0384615384615385 0.45429950277859 0.899901477022066 0.986044462276037 GO:0051139 metal cation:proton antiporter activity 1/1578 26/18639 0.0384615384615385 0.45429950277859 0.899901477022066 0.986044462276037 GO:0003730 mRNA 3'-UTR binding 17/1578 262/18639 0.0648854961832061 0.766413664992889 0.901893357972992 0.987309442015003 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/1578 45/18639 0.0444444444444444 0.524968314321926 0.903887434855734 0.987658281459602 GO:0140303 intramembrane lipid transporter activity 2/1578 45/18639 0.0444444444444444 0.524968314321926 0.903887434855734 0.987658281459602 GO:0016835 carbon-oxygen lyase activity 4/1578 79/18639 0.0506329113924051 0.598065168214853 0.910764637521785 0.994251395961282 GO:0000049 tRNA binding 4/1578 80/18639 0.05 0.590589353612167 0.915644947764763 0.995526983337846 GO:0005242 inward rectifier potassium channel activity 1/1578 28/18639 0.0357142857142857 0.421849538294405 0.916155027075117 0.995526983337846 GO:0050698 proteoglycan sulfotransferase activity 1/1578 28/18639 0.0357142857142857 0.421849538294405 0.916155027075117 0.995526983337846 GO:0051019 mitogen-activated protein kinase binding 1/1578 28/18639 0.0357142857142857 0.421849538294405 0.916155027075117 0.995526983337846 GO:0141052 histone H3 demethylase activity 1/1578 28/18639 0.0357142857142857 0.421849538294405 0.916155027075117 0.995526983337846 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/1578 29/18639 0.0344827586206897 0.40730300249115 0.9232641220875 0.999999952093203 GO:0035254 glutamate receptor binding 2/1578 49/18639 0.0408163265306122 0.482113758050749 0.927745513145468 0.999999952093203 GO:0048019 receptor antagonist activity 1/1578 30/18639 0.0333333333333333 0.393726235741445 0.92977079674338 0.999999952093203 GO:0051721 protein phosphatase 2A binding 1/1578 30/18639 0.0333333333333333 0.393726235741445 0.92977079674338 0.999999952093203 GO:0070566 adenylyltransferase activity 1/1578 30/18639 0.0333333333333333 0.393726235741445 0.92977079674338 0.999999952093203 GO:0005261 monoatomic cation channel activity 22/1578 341/18639 0.0645161290322581 0.762050778854409 0.930675055000795 0.999999952093203 GO:0042054 histone methyltransferase activity 3/1578 67/18639 0.0447761194029851 0.528885988309404 0.930711712176928 0.999999952093203 GO:0008168 methyltransferase activity 12/1578 204/18639 0.0588235294117647 0.694811004249609 0.934210122564822 0.999999952093203 GO:0005262 calcium channel activity 7/1578 131/18639 0.0534351145038168 0.631164194700026 0.934268434702097 0.999999952093203 GO:0005164 tumor necrosis factor receptor binding 1/1578 31/18639 0.032258064516129 0.381025389427205 0.935726070145441 0.999999952093203 GO:0005184 neuropeptide hormone activity 1/1578 31/18639 0.032258064516129 0.381025389427205 0.935726070145441 0.999999952093203 GO:0005179 hormone activity 7/1578 132/18639 0.053030303030303 0.62638264777048 0.937328724889448 0.999999952093203 GO:0015085 calcium ion transmembrane transporter activity 8/1578 147/18639 0.054421768707483 0.642818344067665 0.937338187473842 0.999999952093203 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/1578 32/18639 0.03125 0.369118346007605 0.94117664308775 0.999999952093203 GO:0051059 NF-kappaB binding 1/1578 32/18639 0.03125 0.369118346007605 0.94117664308775 0.999999952093203 GO:0160041 neuropeptide activity 1/1578 32/18639 0.03125 0.369118346007605 0.94117664308775 0.999999952093203 GO:0008028 monocarboxylic acid transmembrane transporter activity 3/1578 70/18639 0.0428571428571429 0.506219445953286 0.942784370040084 0.999999952093203 GO:0016782 transferase activity, transferring sulphur-containing groups 3/1578 70/18639 0.0428571428571429 0.506219445953286 0.942784370040084 0.999999952093203 GO:0008146 sulfotransferase activity 2/1578 53/18639 0.0377358490566038 0.445727814046919 0.945928477846015 0.999999952093203 GO:0019956 chemokine binding 1/1578 33/18639 0.0303030303030303 0.357932941583132 0.946165263349347 0.999999952093203 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 10/1578 181/18639 0.0552486187845304 0.652584921118417 0.948420200883143 0.999999952093203 GO:0008175 tRNA methyltransferase activity 1/1578 34/18639 0.0294117647058824 0.347405502124804 0.950731060104949 0.999999952093203 GO:0015020 glucuronosyltransferase activity 1/1578 34/18639 0.0294117647058824 0.347405502124804 0.950731060104949 0.999999952093203 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/1578 34/18639 0.0294117647058824 0.347405502124804 0.950731060104949 0.999999952093203 GO:0008514 organic anion transmembrane transporter activity 16/1578 269/18639 0.0594795539033457 0.70255982585834 0.951722239675511 0.999999952093203 GO:0003774 cytoskeletal motor activity 8/1578 153/18639 0.0522875816993464 0.617609781555208 0.952536807401515 0.999999952093203 GO:0008374 O-acyltransferase activity 2/1578 55/18639 0.0363636363636364 0.429519529899758 0.953296077914897 0.999999952093203 GO:0016229 steroid dehydrogenase activity 1/1578 35/18639 0.0285714285714286 0.337479630635524 0.954909850062186 0.999999952093203 GO:0072341 modified amino acid binding 4/1578 91/18639 0.043956043956044 0.51919943174696 0.955506375406193 0.999999952093203 GO:0030170 pyridoxal phosphate binding 2/1578 56/18639 0.0357142857142857 0.421849538294405 0.956609911816158 0.999999952093203 GO:0170055 lipid transmembrane transporter activity 2/1578 56/18639 0.0357142857142857 0.421849538294405 0.956609911816158 0.999999952093203 GO:0004843 cysteine-type deubiquitinase activity 5/1578 108/18639 0.0462962962962963 0.54684199408534 0.956865916749049 0.999999952093203 GO:0070279 vitamin B6 binding 2/1578 57/18639 0.0350877192982456 0.414448669201521 0.959697845457258 0.999999952093203 GO:0046943 carboxylic acid transmembrane transporter activity 10/1578 188/18639 0.0531914893617021 0.628286546395923 0.962025449562774 0.999999952093203 GO:0019213 deacetylase activity 1/1578 37/18639 0.027027027027027 0.319237488439009 0.962234771896346 0.999999952093203 GO:0005342 organic acid transmembrane transporter activity 10/1578 189/18639 0.0529100529100529 0.624962278954674 0.963682006829806 0.999999952093203 GO:0070888 E-box binding 2/1578 59/18639 0.0338983050847458 0.400399561770961 0.965253053212572 0.999999952093203 GO:0000146 microfilament motor activity 1/1578 38/18639 0.0263157894736842 0.310836501901141 0.965438380645275 0.999999952093203 GO:0005501 retinoid binding 1/1578 38/18639 0.0263157894736842 0.310836501901141 0.965438380645275 0.999999952093203 GO:0019840 isoprenoid binding 1/1578 38/18639 0.0263157894736842 0.310836501901141 0.965438380645275 0.999999952093203 GO:0019905 syntaxin binding 2/1578 61/18639 0.0327868852459016 0.387271707286667 0.970067716290972 0.999999952093203 GO:0008170 N-methyltransferase activity 4/1578 98/18639 0.0408163265306122 0.482113758050749 0.970910014606264 0.999999952093203 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/1578 41/18639 0.024390243902439 0.288092367615691 0.973509691963771 0.999999952093203 GO:0008227 G protein-coupled amine receptor activity 1/1578 41/18639 0.024390243902439 0.288092367615691 0.973509691963771 0.999999952093203 GO:0005254 chloride channel activity 3/1578 83/18639 0.036144578313253 0.426932062852169 0.975749734225206 0.999999952093203 GO:0008200 ion channel inhibitor activity 1/1578 43/18639 0.0232558139534884 0.27469272261031 0.977814385211941 0.999999952093203 GO:0016248 channel inhibitor activity 1/1578 44/18639 0.0227272727272727 0.268449706187349 0.979696989004991 0.999999952093203 GO:0030547 signaling receptor inhibitor activity 1/1578 44/18639 0.0227272727272727 0.268449706187349 0.979696989004991 0.999999952093203 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 5/1578 122/18639 0.040983606557377 0.484089634108334 0.980716713972565 0.999999952093203 GO:0008173 RNA methyltransferase activity 2/1578 67/18639 0.0298507462686567 0.352590658872936 0.980953879150734 0.999999952093203 GO:0005125 cytokine activity 12/1578 234/18639 0.0512820512820513 0.605732670371454 0.981267085952781 0.999999952093203 GO:0042605 peptide antigen binding 1/1578 45/18639 0.0222222222222222 0.262484157160963 0.981419933417474 0.999999952093203 GO:0141110 transporter inhibitor activity 1/1578 45/18639 0.0222222222222222 0.262484157160963 0.981419933417474 0.999999952093203 GO:0003777 microtubule motor activity 2/1578 68/18639 0.0294117647058824 0.347405502124804 0.982347172198409 0.999999952093203 GO:0015631 tubulin binding 22/1578 385/18639 0.0571428571428571 0.674959261271048 0.984142976786606 0.999999952093203 GO:0005516 calmodulin binding 10/1578 207/18639 0.0483091787439614 0.570617732958616 0.984274776522281 0.999999952093203 GO:0140938 histone H3 methyltransferase activity 1/1578 47/18639 0.0212765957446809 0.251314618558369 0.984439827746623 0.999999952093203 GO:0008236 serine-type peptidase activity 9/1578 194/18639 0.0463917525773196 0.547969503351496 0.986287932447859 0.999999952093203 GO:0005216 monoatomic ion channel activity 26/1578 448/18639 0.0580357142857143 0.685505499728409 0.987182099656292 0.999999952093203 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 5/1578 130/18639 0.0384615384615385 0.45429950277859 0.988066591450631 0.999999952093203 GO:0017171 serine hydrolase activity 9/1578 198/18639 0.0454545454545455 0.536899412374698 0.988808521699748 0.999999952093203 GO:0008017 microtubule binding 14/1578 276/18639 0.0507246376811594 0.599148619606547 0.988825408751313 0.999999952093203 GO:0005272 sodium channel activity 1/1578 51/18639 0.0196078431372549 0.231603668083203 0.989087539851414 0.999999952093203 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/1578 56/18639 0.0178571428571429 0.210924769147203 0.992997401259757 0.999999952093203 GO:0015108 chloride transmembrane transporter activity 4/1578 121/18639 0.0330578512396694 0.390472299908871 0.993339688488669 0.999999952093203 GO:0005253 monoatomic anion channel activity 3/1578 103/18639 0.029126213592233 0.344032633172136 0.99397428338866 0.999999952093203 GO:0098960 postsynaptic neurotransmitter receptor activity 1/1578 69/18639 0.0144927536231884 0.171185319887585 0.99779158582833 0.999999952093203 GO:0004252 serine-type endopeptidase activity 6/1578 176/18639 0.0340909090909091 0.402674559281023 0.997880708462559 0.999999952093203 GO:0030594 neurotransmitter receptor activity 2/1578 97/18639 0.0206185567010309 0.243542001489554 0.998161999475652 0.999999952093203 GO:0015291 secondary active transmembrane transporter activity 12/1578 287/18639 0.0418118466898955 0.493872630198328 0.998589404347274 0.999999952093203 GO:0015103 inorganic anion transmembrane transporter activity 5/1578 165/18639 0.0303030303030303 0.357932941583132 0.998720837376501 0.999999952093203 GO:0008509 monoatomic anion transmembrane transporter activity 4/1578 149/18639 0.0268456375838926 0.317094954959553 0.999020173032689 0.999999952093203 GO:0099094 ligand-gated monoatomic cation channel activity 3/1578 136/18639 0.0220588235294118 0.260554126593603 0.999468306220914 0.999999952093203 GO:0141108 transporter regulator activity 4/1578 170/18639 0.0235294117647059 0.277924401699843 0.999781727705835 0.999999952093203 GO:0005249 voltage-gated potassium channel activity 1/1578 98/18639 0.0102040816326531 0.120528439512687 0.99983221888626 0.999999952093203 GO:0001653 peptide receptor activity 2/1578 128/18639 0.015625 0.184559173003802 0.9998498928705 0.999999952093203 GO:0015079 potassium ion transmembrane transporter activity 3/1578 160/18639 0.01875 0.221471007604563 0.999915196237195 0.999999952093203 GO:0099106 ion channel regulator activity 3/1578 160/18639 0.01875 0.221471007604563 0.999915196237195 0.999999952093203 GO:0015081 sodium ion transmembrane transporter activity 3/1578 164/18639 0.0182926829268293 0.216069275711769 0.999937824386496 0.999999952093203 GO:0016247 channel regulator activity 3/1578 168/18639 0.0178571428571429 0.210924769147203 0.999954465745438 0.999999952093203 GO:0015293 symporter activity 2/1578 146/18639 0.0136986301369863 0.161805302359498 0.999965884587587 0.999999952093203 GO:0015294 solute:monoatomic cation symporter activity 1/1578 116/18639 0.00862068965517241 0.101825750622787 0.999966188797655 0.999999952093203 GO:0005244 voltage-gated monoatomic ion channel activity 3/1578 173/18639 0.0173410404624277 0.204828677553353 0.999969197825792 0.999999952093203 GO:0003823 antigen binding 3/1578 174/18639 0.0172413793103448 0.203651501245575 0.999971519629626 0.999999952093203 GO:0022832 voltage-gated channel activity 3/1578 175/18639 0.0171428571428571 0.202487778381315 0.999973668086612 0.999999952093203 GO:0046873 metal ion transmembrane transporter activity 17/1578 450/18639 0.0377777777777778 0.446223067173638 0.999979297889368 0.999999952093203 GO:0008528 G protein-coupled peptide receptor activity 1/1578 122/18639 0.00819672131147541 0.0968179268216668 0.999980184303802 0.999999952093203 GO:0005267 potassium channel activity 1/1578 124/18639 0.00806451612903226 0.0952563473568012 0.999983417827329 0.999999952093203 GO:0015276 ligand-gated monoatomic ion channel activity 3/1578 186/18639 0.0161290322580645 0.190512694713602 0.999988932547679 0.999999952093203 GO:0022834 ligand-gated channel activity 3/1578 188/18639 0.0159574468085106 0.188485963918777 0.999990553364336 0.999999952093203 GO:0045182 translation regulator activity 11/1578 356/18639 0.0308988764044944 0.364970948861452 0.999990564777463 0.999999952093203 GO:0022843 voltage-gated monoatomic cation channel activity 1/1578 143/18639 0.00699300699300699 0.0825999095961073 0.999996950630019 0.999999952093203 GO:0022836 gated channel activity 6/1578 318/18639 0.0188679245283019 0.222863907023459 0.999999890893716 0.999999952093203 GO:0030371 translation repressor activity 6/1578 329/18639 0.0182370820668693 0.215412530192888 0.999999952093203 0.999999952093203