ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 86/1020 175/18639 0.491428571428571 8.98013445378151 2.74655258883579e-61 2.76577845695764e-58 GO:0016209 antioxidant activity 25/1020 86/18639 0.290697674418605 5.31207250341997 2.65737427710806e-12 1.33798794852391e-09 GO:0015078 proton transmembrane transporter activity 37/1020 185/18639 0.2 3.65470588235294 5.15665571387396e-12 1.43646500399903e-09 GO:0005201 extracellular matrix structural constituent 35/1020 168/18639 0.208333333333333 3.80698529411765 5.70591858589485e-12 1.43646500399903e-09 GO:0019843 rRNA binding 21/1020 65/18639 0.323076923076923 5.9037556561086 1.57329312026834e-11 2.94991169338659e-09 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 20/1020 59/18639 0.338983050847458 6.19441674975075 1.75764351145179e-11 2.94991169338659e-09 GO:0004601 peroxidase activity 19/1020 57/18639 0.333333333333333 6.09117647058823 7.8817961889422e-11 1.07480106516374e-08 GO:0045296 cadherin binding 50/1020 334/18639 0.149700598802395 2.73555829517436 8.53863805492547e-11 1.07480106516374e-08 GO:0022853 active monoatomic ion transmembrane transporter activity 26/1020 118/18639 0.220338983050847 4.02637088733799 8.4079958102018e-10 9.40761308985913e-08 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 10/1020 18/18639 0.555555555555556 10.1519607843137 6.74994439300316e-09 6.79719400375418e-07 GO:0009055 electron transfer activity 24/1020 116/18639 0.206896551724138 3.78073022312373 1.3969260503739e-08 1.27882230247865e-06 GO:0048027 mRNA 5'-UTR binding 11/1020 24/18639 0.458333333333333 8.37536764705882 1.61457107526261e-08 1.35489422732454e-06 GO:0015399 primary active transmembrane transporter activity 28/1020 166/18639 0.168674698795181 3.08228206945429 9.65557758949202e-08 7.09799798197704e-06 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 17/1020 68/18639 0.25 4.56838235294118 9.86812033244077e-08 7.09799798197704e-06 GO:0055105 ubiquitin-protein transferase inhibitor activity 8/1020 15/18639 0.533333333333333 9.74588235294117 3.56862845733907e-07 2.39573923769363e-05 GO:1990948 ubiquitin ligase inhibitor activity 7/1020 11/18639 0.636363636363636 11.6286096256684 3.91481063365508e-07 2.46388394255666e-05 GO:0015252 proton channel activity 10/1020 27/18639 0.37037037037037 6.76797385620915 8.2758667402768e-07 4.9022340043875e-05 GO:0005344 oxygen carrier activity 7/1020 14/18639 0.5 9.13676470588235 3.51954743126241e-06 0.000196899125737847 GO:0031720 haptoglobin binding 6/1020 10/18639 0.6 10.9641176470588 4.5959869264391e-06 0.000243587307101273 GO:0031386 protein tag activity 7/1020 15/18639 0.466666666666667 8.52764705882353 6.28689644359987e-06 0.00030147165327167 GO:0141047 molecular tag activity 7/1020 15/18639 0.466666666666667 8.52764705882353 6.28689644359987e-06 0.00030147165327167 GO:0004857 enzyme inhibitor activity 45/1020 416/18639 0.108173076923077 1.97670390271493 1.02664134030744e-05 0.000469921740767996 GO:0050840 extracellular matrix binding 14/1020 67/18639 0.208955223880597 3.81834942932397 1.27188652516587e-05 0.0005568651003661 GO:0002020 protease binding 21/1020 136/18639 0.154411764705882 2.82164792387543 1.55741689309445e-05 0.000653466171394215 GO:0005178 integrin binding 23/1020 161/18639 0.142857142857143 2.61050420168067 2.29042429350948e-05 0.000915595081002021 GO:0022804 active transmembrane transporter activity 47/1020 457/18639 0.102844638949672 1.87933453468915 2.44723112074055e-05 0.000915595081002021 GO:0005539 glycosaminoglycan binding 30/1020 242/18639 0.12396694214876 2.26531356344191 2.4549222628654e-05 0.000915595081002021 GO:1901681 sulfur compound binding 32/1020 275/18639 0.116363636363636 2.1263743315508 4.73365912749609e-05 0.00170242669335306 GO:0019838 growth factor binding 20/1020 136/18639 0.147058823529412 2.68728373702422 5.05064808441968e-05 0.00175379400724504 GO:0008201 heparin binding 23/1020 172/18639 0.133720930232558 2.44355335157319 6.5974946535364e-05 0.00221455903870372 GO:0005518 collagen binding 13/1020 72/18639 0.180555555555556 3.29938725490196 0.000127591989709051 0.00414468173022626 GO:0016675 oxidoreductase activity, acting on a heme group of donors 6/1020 16/18639 0.375 6.85257352941176 0.000131837810427665 0.00414877109689557 GO:0010854 adenylate cyclase regulator activity 5/1020 11/18639 0.454545454545455 8.30614973262032 0.000170161557310691 0.0048957910917676 GO:0019864 IgG binding 5/1020 11/18639 0.454545454545455 8.30614973262032 0.000170161557310691 0.0048957910917676 GO:0048407 platelet-derived growth factor binding 5/1020 11/18639 0.454545454545455 8.30614973262032 0.000170161557310691 0.0048957910917676 GO:0038024 cargo receptor activity 12/1020 65/18639 0.184615384615385 3.37357466063348 0.000184739691760517 0.00509051383959465 GO:0005504 fatty acid binding 10/1020 47/18639 0.212765957446809 3.88798498122653 0.000187039733927509 0.00509051383959465 GO:0051015 actin filament binding 25/1020 209/18639 0.119617224880383 2.18582887700535 0.000200068703352781 0.00530182063884869 GO:0042625 ATPase-coupled ion transmembrane transporter activity 7/1020 24/18639 0.291666666666667 5.32977941176471 0.000218989777055479 0.00537860257304555 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 7/1020 24/18639 0.291666666666667 5.32977941176471 0.000218989777055479 0.00537860257304555 GO:0046961 proton-transporting ATPase activity, rotational mechanism 7/1020 24/18639 0.291666666666667 5.32977941176471 0.000218989777055479 0.00537860257304555 GO:0003746 translation elongation factor activity 6/1020 18/18639 0.333333333333333 6.09117647058823 0.000278067900744756 0.00666700895357069 GO:0008137 NADH dehydrogenase (ubiquinone) activity 9/1020 41/18639 0.219512195121951 4.01126255380201 0.000304329560264792 0.00712697365550339 GO:0048487 beta-tubulin binding 9/1020 42/18639 0.214285714285714 3.91575630252101 0.000368737443525435 0.00843905921886621 GO:0005044 scavenger receptor activity 7/1020 27/18639 0.259259259259259 4.73758169934641 0.000486503338146819 0.0108868635891966 GO:0003954 NADH dehydrogenase activity 9/1020 44/18639 0.204545454545455 3.73776737967914 0.000531383943910159 0.0113851836493092 GO:0030020 extracellular matrix structural constituent conferring tensile strength 9/1020 44/18639 0.204545454545455 3.73776737967914 0.000531383943910159 0.0113851836493092 GO:0008135 translation factor activity, RNA binding 13/1020 83/18639 0.156626506024096 2.86211906449327 0.000545889870600158 0.0114523145769658 GO:0055106 ubiquitin-protein transferase regulator activity 8/1020 36/18639 0.222222222222222 4.06078431372549 0.000600480756762954 0.0123404922869448 GO:0180051 translation factor activity 13/1020 84/18639 0.154761904761905 2.8280462184874 0.000614083004435297 0.0123676317093269 GO:0061134 peptidase regulator activity 25/1020 226/18639 0.110619469026549 2.02140812077043 0.000656220973417608 0.0129571474555202 GO:0043021 ribonucleoprotein complex binding 21/1020 177/18639 0.11864406779661 2.16804586241276 0.000698040968299527 0.0134079517523969 GO:0072542 protein phosphatase activator activity 6/1020 21/18639 0.285714285714286 5.22100840336134 0.000705681671178783 0.0134079517523969 GO:0003785 actin monomer binding 7/1020 29/18639 0.241379310344828 4.41085192697769 0.000776944195704033 0.0144885704643326 GO:0051082 unfolded protein binding 16/1020 121/18639 0.132231404958678 2.41633446767137 0.000920038953120567 0.0160730826048563 GO:0004129 cytochrome-c oxidase activity 5/1020 15/18639 0.333333333333333 6.09117647058823 0.000920271260190418 0.0160730826048563 GO:0005523 tropomyosin binding 5/1020 15/18639 0.333333333333333 6.09117647058823 0.000920271260190418 0.0160730826048563 GO:0140517 protein-RNA adaptor activity 6/1020 22/18639 0.272727272727273 4.98368983957219 0.000925758481709698 0.0160730826048563 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 10/1020 58/18639 0.172413793103448 3.15060851926978 0.00109285235664471 0.0186525817481563 GO:0043022 ribosome binding 15/1020 112/18639 0.133928571428571 2.44734768907563 0.0011509579612054 0.0193169111155639 GO:0004602 glutathione peroxidase activity 6/1020 23/18639 0.260869565217391 4.76700767263427 0.00119505146221475 0.0195253698319589 GO:0031625 ubiquitin protein ligase binding 30/1020 302/18639 0.0993377483443709 1.81525126606934 0.00120215782480779 0.0195253698319589 GO:0008239 dipeptidyl-peptidase activity 4/1020 10/18639 0.4 7.30941176470588 0.00143503344217927 0.0229377567662623 GO:0005021 vascular endothelial growth factor receptor activity 9/1020 51/18639 0.176470588235294 3.22474048442907 0.00161832855319845 0.0254633883292319 GO:0044389 ubiquitin-like protein ligase binding 31/1020 322/18639 0.0962732919254658 1.75925283156741 0.00166066595532035 0.025727547953963 GO:0019211 phosphatase activator activity 6/1020 25/18639 0.24 4.38564705882353 0.00190899207642163 0.0291265912266149 GO:0019825 oxygen binding 7/1020 34/18639 0.205882352941176 3.76219723183391 0.00210921355135252 0.0317011648688356 GO:0097493 structural molecule activity conferring elasticity 4/1020 11/18639 0.363636363636364 6.64491978609626 0.00215781737638989 0.0319547367356561 GO:0098641 cadherin binding involved in cell-cell adhesion 5/1020 18/18639 0.277777777777778 5.07598039215686 0.00228905180718572 0.033076401615383 GO:0033218 amide binding 25/1020 247/18639 0.101214574898785 1.84954751131222 0.00229925333969892 0.033076401615383 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 9/1020 54/18639 0.166666666666667 3.04558823529412 0.00244340153797298 0.034655004911814 GO:0098631 cell adhesion mediator activity 11/1020 76/18639 0.144736842105263 2.64485294117647 0.00272814563927744 0.0381561480382275 GO:0016651 oxidoreductase activity, acting on NAD(P)H 12/1020 88/18639 0.136363636363636 2.4918449197861 0.00297642167902906 0.041058310010716 GO:0010853 cyclase activator activity 4/1020 12/18639 0.333333333333333 6.09117647058823 0.00309744037095782 0.041588299380727 GO:1990247 N6-methyladenosine-containing RNA reader activity 4/1020 12/18639 0.333333333333333 6.09117647058823 0.00309744037095782 0.041588299380727 GO:0016500 protein-hormone receptor activity 10/1020 67/18639 0.149253731343284 2.72739244951712 0.00333410439639968 0.0440014389049694 GO:0008083 growth factor activity 18/1020 162/18639 0.111111111111111 2.03039215686274 0.00336455888349816 0.0440014389049694 GO:0043394 proteoglycan binding 7/1020 37/18639 0.189189189189189 3.45715421303657 0.00349987844142971 0.0451843280835862 GO:0016504 peptidase activator activity 9/1020 57/18639 0.157894736842105 2.88529411764706 0.00357149394616679 0.0455252456175944 GO:0033293 monocarboxylic acid binding 11/1020 79/18639 0.139240506329114 2.54441548771407 0.00371082263387251 0.0467099799038702 GO:0010851 cyclase regulator activity 5/1020 20/18639 0.25 4.56838235294118 0.00378136738243532 0.0470103327668194 GO:0035325 Toll-like receptor binding 4/1020 13/18639 0.307692307692308 5.62262443438914 0.0042819360354832 0.0511602131502073 GO:0070700 BMP receptor binding 4/1020 13/18639 0.307692307692308 5.62262443438914 0.0042819360354832 0.0511602131502073 GO:0001846 opsonin binding 5/1020 21/18639 0.238095238095238 4.35084033613445 0.00474251916720298 0.0511602131502073 GO:0005004 GPI-linked ephrin receptor activity 8/1020 49/18639 0.163265306122449 2.98343337334934 0.00477563062176712 0.0511602131502073 GO:0005008 hepatocyte growth factor receptor activity 8/1020 49/18639 0.163265306122449 2.98343337334934 0.00477563062176712 0.0511602131502073 GO:0005009 insulin receptor activity 8/1020 49/18639 0.163265306122449 2.98343337334934 0.00477563062176712 0.0511602131502073 GO:0005011 macrophage colony-stimulating factor receptor activity 8/1020 49/18639 0.163265306122449 2.98343337334934 0.00477563062176712 0.0511602131502073 GO:0005018 platelet-derived growth factor alpha-receptor activity 8/1020 49/18639 0.163265306122449 2.98343337334934 0.00477563062176712 0.0511602131502073 GO:0005020 stem cell factor receptor activity 8/1020 49/18639 0.163265306122449 2.98343337334934 0.00477563062176712 0.0511602131502073 GO:0008288 boss receptor activity 8/1020 49/18639 0.163265306122449 2.98343337334934 0.00477563062176712 0.0511602131502073 GO:0036332 placental growth factor receptor activity 8/1020 49/18639 0.163265306122449 2.98343337334934 0.00477563062176712 0.0511602131502073 GO:0038062 protein tyrosine kinase collagen receptor activity 8/1020 49/18639 0.163265306122449 2.98343337334934 0.00477563062176712 0.0511602131502073 GO:0060175 brain-derived neurotrophic factor receptor activity 8/1020 49/18639 0.163265306122449 2.98343337334934 0.00477563062176712 0.0511602131502073 GO:0001968 fibronectin binding 6/1020 30/18639 0.2 3.65470588235294 0.0050684053280773 0.053123883125876 GO:0004714 transmembrane receptor protein tyrosine kinase activity 9/1020 60/18639 0.15 2.74102941176471 0.00507238856779405 0.053123883125876 GO:0042562 hormone binding 12/1020 94/18639 0.127659574468085 2.33279098873592 0.00513511258296986 0.053123883125876 GO:0042277 peptide binding 24/1020 249/18639 0.0963855421686747 1.76130403968816 0.00516995089010511 0.053123883125876 GO:0005006 epidermal growth factor receptor activity 8/1020 50/18639 0.16 2.92376470588235 0.00541869906255637 0.0534963721175909 GO:0005007 fibroblast growth factor receptor activity 8/1020 50/18639 0.16 2.92376470588235 0.00541869906255637 0.0534963721175909 GO:0005017 platelet-derived growth factor receptor activity 8/1020 50/18639 0.16 2.92376470588235 0.00541869906255637 0.0534963721175909 GO:0005019 platelet-derived growth factor beta-receptor activity 8/1020 50/18639 0.16 2.92376470588235 0.00541869906255637 0.0534963721175909 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 7/1020 40/18639 0.175 3.19786764705882 0.00549746776869047 0.0537470877968087 GO:0019763 immunoglobulin receptor activity 4/1020 14/18639 0.285714285714286 5.22100840336134 0.00573778588236283 0.0550280988908511 GO:0032036 myosin heavy chain binding 4/1020 14/18639 0.285714285714286 5.22100840336134 0.00573778588236283 0.0550280988908511 GO:0030021 extracellular matrix structural constituent conferring compression resistance 5/1020 22/18639 0.227272727272727 4.15307486631016 0.0058650958394069 0.0557184104743655 GO:0017147 Wnt-protein binding 6/1020 31/18639 0.193548387096774 3.53681214421252 0.00599931787264099 0.056460870072425 GO:0005010 insulin-like growth factor receptor activity 8/1020 51/18639 0.156862745098039 2.86643598615917 0.00612574473871599 0.0565928894668532 GO:0005030 neurotrophin receptor activity 8/1020 51/18639 0.156862745098039 2.86643598615917 0.00612574473871599 0.0565928894668532 GO:0001530 lipopolysaccharide binding 7/1020 41/18639 0.170731707317073 3.11987087517934 0.00632294981874619 0.057883731522522 GO:0044325 transmembrane transporter binding 15/1020 136/18639 0.110294117647059 2.01546280276817 0.00754383148777228 0.0684349780248404 GO:0005003 ephrin receptor activity 8/1020 53/18639 0.150943396226415 2.75826859045505 0.00774735600281213 0.0684349780248404 GO:0005005 transmembrane-ephrin receptor activity 8/1020 53/18639 0.150943396226415 2.75826859045505 0.00774735600281213 0.0684349780248404 GO:0038064 collagen receptor activity 8/1020 53/18639 0.150943396226415 2.75826859045505 0.00774735600281213 0.0684349780248404 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 5/1020 24/18639 0.208333333333333 3.80698529411765 0.00864704750214249 0.0757180594318042 GO:0005159 insulin-like growth factor receptor binding 4/1020 16/18639 0.25 4.56838235294118 0.00955992914144894 0.0822807576533255 GO:0043023 ribosomal large subunit binding 4/1020 16/18639 0.25 4.56838235294118 0.00955992914144894 0.0822807576533255 GO:0098632 cell-cell adhesion mediator activity 8/1020 55/18639 0.145454545454545 2.6579679144385 0.00967188315608233 0.0825388672726687 GO:0019199 transmembrane receptor protein kinase activity 10/1020 78/18639 0.128205128205128 2.34276018099547 0.00987505918780971 0.0835645764884402 GO:0001848 complement binding 5/1020 25/18639 0.2 3.65470588235294 0.0103315613585727 0.0866990190673558 GO:0046332 SMAD binding 10/1020 79/18639 0.126582278481013 2.31310498883098 0.0107684268043223 0.0896182296855587 GO:0048306 calcium-dependent protein binding 10/1020 80/18639 0.125 2.28419117647059 0.0117217900524088 0.0967528080555384 GO:0008429 phosphatidylethanolamine binding 4/1020 17/18639 0.235294117647059 4.29965397923875 0.0119690011337386 0.0971998721102801 GO:0045125 bioactive lipid receptor activity 4/1020 17/18639 0.235294117647059 4.29965397923875 0.0119690011337386 0.0971998721102801 GO:0019865 immunoglobulin binding 5/1020 26/18639 0.192307692307692 3.51414027149321 0.012227584280344 0.0977236299230671 GO:0030247 polysaccharide binding 5/1020 26/18639 0.192307692307692 3.51414027149321 0.012227584280344 0.0977236299230671 GO:0019955 cytokine binding 15/1020 144/18639 0.104166666666667 1.90349264705882 0.012463442492667 0.0988243038591785 GO:0001618 virus receptor activity 10/1020 81/18639 0.123456790123457 2.25599128540305 0.0127375424274029 0.100208634565584 GO:0097110 scaffold protein binding 9/1020 70/18639 0.128571428571429 2.3494537815126 0.0137575803196482 0.107036914784351 GO:0140272 exogenous protein binding 10/1020 82/18639 0.121951219512195 2.22847919655667 0.0138180724150603 0.107036914784351 GO:0004364 glutathione transferase activity 5/1020 27/18639 0.185185185185185 3.38398692810458 0.0143461463210747 0.110279155307803 GO:0038187 pattern recognition receptor activity 7/1020 48/18639 0.145833333333333 2.66488970588235 0.0148909675115758 0.113600032455733 GO:0005543 phospholipid binding 39/1020 497/18639 0.0784708249496982 1.43393892768375 0.0152740954701958 0.115646722845768 GO:0042626 ATPase-coupled transmembrane transporter activity 11/1020 98/18639 0.112244897959184 2.05111044417767 0.018077862319105 0.135853786233871 GO:0140297 DNA-binding transcription factor binding 38/1020 488/18639 0.0778688524590164 1.4229387656702 0.0183887161847443 0.137166201466945 GO:0003779 actin binding 35/1020 443/18639 0.0790067720090293 1.44373257203559 0.018921670639713 0.139315086363971 GO:0015217 ADP transmembrane transporter activity 3/1020 11/18639 0.272727272727273 4.98368983957219 0.019368532364405 0.139315086363971 GO:0042608 T cell receptor binding 3/1020 11/18639 0.272727272727273 4.98368983957219 0.019368532364405 0.139315086363971 GO:0050786 RAGE receptor binding 3/1020 11/18639 0.272727272727273 4.98368983957219 0.019368532364405 0.139315086363971 GO:0070990 snRNP binding 3/1020 11/18639 0.272727272727273 4.98368983957219 0.019368532364405 0.139315086363971 GO:0003743 translation initiation factor activity 7/1020 51/18639 0.137254901960784 2.50813148788927 0.0203449580343556 0.145300515890752 GO:0016505 peptidase activator activity involved in apoptotic process 4/1020 20/18639 0.2 3.65470588235294 0.0213952306507318 0.151725332854133 GO:0004197 cysteine-type endopeptidase activity 10/1020 88/18639 0.113636363636364 2.07653743315508 0.0217933187215846 0.153467636032418 GO:0033612 receptor serine/threonine kinase binding 5/1020 30/18639 0.166666666666667 3.04558823529412 0.0221357467485555 0.154796506776357 GO:0030414 peptidase inhibitor activity 16/1020 169/18639 0.0946745562130177 1.73003828750435 0.0231537132691277 0.160798546634563 GO:0008238 exopeptidase activity 11/1020 102/18639 0.107843137254902 1.97067474048443 0.0236469254261955 0.162746547317902 GO:0020037 heme binding 14/1020 142/18639 0.0985915492957746 1.80161557580779 0.0237574403731197 0.162746547317902 GO:0140375 immune receptor activity 15/1020 156/18639 0.0961538461538462 1.75707013574661 0.024143043814026 0.163175001983157 GO:0061135 endopeptidase regulator activity 17/1020 184/18639 0.0923913043478261 1.6883152173913 0.0243073929597474 0.163175001983157 GO:0004859 phospholipase inhibitor activity 3/1020 12/18639 0.25 4.56838235294118 0.0247922296955542 0.163175001983157 GO:0004875 complement receptor activity 3/1020 12/18639 0.25 4.56838235294118 0.0247922296955542 0.163175001983157 GO:0035497 cAMP response element binding 3/1020 12/18639 0.25 4.56838235294118 0.0247922296955542 0.163175001983157 GO:0097371 MDM2/MDM4 family protein binding 3/1020 12/18639 0.25 4.56838235294118 0.0247922296955542 0.163175001983157 GO:0070325 lipoprotein particle receptor binding 5/1020 31/18639 0.161290322580645 2.94734345351044 0.0252389061477699 0.164456195584642 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 4/1020 21/18639 0.19047619047619 3.48067226890756 0.0253135157056797 0.164456195584642 GO:0042056 chemoattractant activity 6/1020 42/18639 0.142857142857143 2.61050420168067 0.0257353284836282 0.166124844762907 GO:0019207 kinase regulator activity 24/1020 287/18639 0.0836236933797909 1.528100020496 0.0260042451755287 0.166791559820111 GO:0019208 phosphatase regulator activity 12/1020 117/18639 0.102564102564103 1.87420814479638 0.0264927223238514 0.168849185950116 GO:0031406 carboxylic acid binding 17/1020 187/18639 0.0909090909090909 1.66122994652406 0.0278785874263844 0.175480581675222 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 28/1020 349/18639 0.0802292263610315 1.46607112759144 0.0278817210208893 0.175480581675222 GO:0008200 ion channel inhibitor activity 6/1020 43/18639 0.13953488372093 2.54979480164159 0.0285714556297597 0.178704694528994 GO:0061133 endopeptidase activator activity 4/1020 22/18639 0.181818181818182 3.32245989304813 0.0296353867870737 0.184215027744341 GO:0043177 organic acid binding 17/1020 189/18639 0.0899470899470899 1.64365079365079 0.0304681585992589 0.187722500109219 GO:0019855 calcium channel inhibitor activity 3/1020 13/18639 0.230769230769231 4.21696832579186 0.0309453177935754 0.187722500109219 GO:0031432 titin binding 3/1020 13/18639 0.230769230769231 4.21696832579186 0.0309453177935754 0.187722500109219 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 3/1020 13/18639 0.230769230769231 4.21696832579186 0.0309453177935754 0.187722500109219 GO:0016248 channel inhibitor activity 6/1020 44/18639 0.136363636363636 2.4918449197861 0.0316057610573295 0.190580846615154 GO:0019888 protein phosphatase regulator activity 11/1020 107/18639 0.102803738317757 1.8785871357889 0.0322477944782554 0.193294815711924 GO:0005158 insulin receptor binding 4/1020 23/18639 0.173913043478261 3.17800511508951 0.0343665565551678 0.202810985828027 GO:0031681 G-protein beta-subunit binding 4/1020 23/18639 0.173913043478261 3.17800511508951 0.0343665565551678 0.202810985828027 GO:0008009 chemokine activity 6/1020 45/18639 0.133333333333333 2.43647058823529 0.0348424037221933 0.202810985828027 GO:0046915 transition metal ion transmembrane transporter activity 6/1020 45/18639 0.133333333333333 2.43647058823529 0.0348424037221933 0.202810985828027 GO:0141110 transporter inhibitor activity 6/1020 45/18639 0.133333333333333 2.43647058823529 0.0348424037221933 0.202810985828027 GO:0005347 ATP transmembrane transporter activity 3/1020 14/18639 0.214285714285714 3.91575630252101 0.0378200992239061 0.21516858711002 GO:0008191 metalloendopeptidase inhibitor activity 3/1020 14/18639 0.214285714285714 3.91575630252101 0.0378200992239061 0.21516858711002 GO:0044548 S100 protein binding 3/1020 14/18639 0.214285714285714 3.91575630252101 0.0378200992239061 0.21516858711002 GO:0098847 sequence-specific single stranded DNA binding 3/1020 14/18639 0.214285714285714 3.91575630252101 0.0378200992239061 0.21516858711002 GO:0046906 tetrapyrrole binding 14/1020 152/18639 0.0921052631578947 1.68308823529412 0.0392892925921949 0.222271447417642 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 4/1020 24/18639 0.166666666666667 3.04558823529412 0.0395104583657728 0.222273919409683 GO:0019887 protein kinase regulator activity 21/1020 255/18639 0.0823529411764706 1.50487889273356 0.0408415330597883 0.228485687728927 GO:0005200 structural constituent of cytoskeleton 11/1020 112/18639 0.0982142857142857 1.79472163865546 0.0428632510450174 0.238471236476975 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 4/1020 25/18639 0.16 2.92376470588235 0.0450683435100014 0.245809358797531 GO:0120020 cholesterol transfer activity 4/1020 25/18639 0.16 2.92376470588235 0.0450683435100014 0.245809358797531 GO:0005041 low-density lipoprotein particle receptor activity 3/1020 15/18639 0.2 3.65470588235294 0.045402721684549 0.245809358797531 GO:0015929 hexosaminidase activity 3/1020 15/18639 0.2 3.65470588235294 0.045402721684549 0.245809358797531 GO:0050700 CARD domain binding 3/1020 15/18639 0.2 3.65470588235294 0.045402721684549 0.245809358797531 GO:0005126 cytokine receptor binding 22/1020 275/18639 0.08 1.46188235294118 0.0482829204062864 0.260004817375029 GO:0005160 transforming growth factor beta receptor binding 4/1020 26/18639 0.153846153846154 2.81131221719457 0.0510393906426664 0.269092494121283 GO:0008198 ferrous iron binding 4/1020 26/18639 0.153846153846154 2.81131221719457 0.0510393906426664 0.269092494121283 GO:0043548 phosphatidylinositol 3-kinase binding 4/1020 26/18639 0.153846153846154 2.81131221719457 0.0510393906426664 0.269092494121283 GO:0050750 low-density lipoprotein particle receptor binding 4/1020 26/18639 0.153846153846154 2.81131221719457 0.0510393906426664 0.269092494121283 GO:0044183 protein folding chaperone 8/1020 75/18639 0.106666666666667 1.94917647058824 0.0520260173388088 0.27286562218844 GO:0019841 retinol binding 3/1020 16/18639 0.1875 3.42628676470588 0.0536741353483413 0.277178739978358 GO:0055102 lipase inhibitor activity 3/1020 16/18639 0.1875 3.42628676470588 0.0536741353483413 0.277178739978358 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 3/1020 16/18639 0.1875 3.42628676470588 0.0536741353483413 0.277178739978358 GO:0005109 frizzled binding 5/1020 38/18639 0.131578947368421 2.40441176470588 0.0546511722571083 0.280784339096469 GO:0005048 signal sequence binding 6/1020 51/18639 0.117647058823529 2.14982698961938 0.0586819888407563 0.299963262754526 GO:0001664 G protein-coupled receptor binding 23/1020 297/18639 0.0774410774410774 1.41512180629828 0.0595112710666719 0.302665908909791 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 3/1020 17/18639 0.176470588235294 3.22474048442907 0.0626109498228991 0.313677743640096 GO:0016018 cyclosporin A binding 3/1020 17/18639 0.176470588235294 3.22474048442907 0.0626109498228991 0.313677743640096 GO:0030169 low-density lipoprotein particle binding 3/1020 17/18639 0.176470588235294 3.22474048442907 0.0626109498228991 0.313677743640096 GO:0097718 disordered domain specific binding 4/1020 28/18639 0.142857142857143 2.61050420168067 0.0642080408943183 0.319246244131459 GO:0043178 alcohol binding 9/1020 92/18639 0.0978260869565217 1.78762787723785 0.064356492113889 0.319246244131459 GO:0003697 single-stranded DNA binding 11/1020 121/18639 0.0909090909090909 1.66122994652406 0.0675765677561267 0.333576488874606 GO:0017046 peptide hormone binding 6/1020 53/18639 0.113207547169811 2.06870144284129 0.0683549802680649 0.33577300063386 GO:0042287 MHC protein binding 5/1020 41/18639 0.121951219512195 2.22847919655667 0.0715131350014454 0.344509492873973 GO:0030228 lipoprotein particle receptor activity 3/1020 18/18639 0.166666666666667 3.04558823529412 0.0721861995992139 0.344509492873973 GO:0031690 adrenergic receptor binding 3/1020 18/18639 0.166666666666667 3.04558823529412 0.0721861995992139 0.344509492873973 GO:0035615 clathrin adaptor activity 3/1020 18/18639 0.166666666666667 3.04558823529412 0.0721861995992139 0.344509492873973 GO:0070064 proline-rich region binding 3/1020 18/18639 0.166666666666667 3.04558823529412 0.0721861995992139 0.344509492873973 GO:1901611 phosphatidylglycerol binding 3/1020 18/18639 0.166666666666667 3.04558823529412 0.0721861995992139 0.344509492873973 GO:0016859 cis-trans isomerase activity 5/1020 42/18639 0.119047619047619 2.17542016806723 0.0776993250714207 0.367339062661599 GO:0031492 nucleosomal DNA binding 5/1020 42/18639 0.119047619047619 2.17542016806723 0.0776993250714207 0.367339062661599 GO:0008106 alcohol dehydrogenase (NADP+) activity 4/1020 30/18639 0.133333333333333 2.43647058823529 0.0789730432642835 0.371616142837072 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 3/1020 19/18639 0.157894736842105 2.88529411764706 0.0823700261496153 0.377030074239376 GO:0005346 purine ribonucleotide transmembrane transporter activity 3/1020 19/18639 0.157894736842105 2.88529411764706 0.0823700261496153 0.377030074239376 GO:0008301 DNA binding, bending 3/1020 19/18639 0.157894736842105 2.88529411764706 0.0823700261496153 0.377030074239376 GO:0016918 retinal binding 3/1020 19/18639 0.157894736842105 2.88529411764706 0.0823700261496153 0.377030074239376 GO:0043395 heparan sulfate proteoglycan binding 3/1020 19/18639 0.157894736842105 2.88529411764706 0.0823700261496153 0.377030074239376 GO:0097001 ceramide binding 3/1020 19/18639 0.157894736842105 2.88529411764706 0.0823700261496153 0.377030074239376 GO:0001540 amyloid-beta binding 8/1020 83/18639 0.0963855421686747 1.76130403968816 0.0837847465587153 0.380050629660479 GO:0030165 PDZ domain binding 8/1020 83/18639 0.0963855421686747 1.76130403968816 0.0837847465587153 0.380050629660479 GO:0048156 tau protein binding 5/1020 43/18639 0.116279069767442 2.12482900136799 0.0841635184190077 0.380056784968344 GO:0047499 calcium-independent phospholipase A2 activity 4/1020 31/18639 0.129032258064516 2.35787476280835 0.0869336561704337 0.390813356087619 GO:0004860 protein kinase inhibitor activity 8/1020 84/18639 0.0952380952380952 1.74033613445378 0.0884103779598585 0.395685558247011 GO:0042288 MHC class I protein binding 3/1020 20/18639 0.15 2.74102941176471 0.0931302841788302 0.410016033838844 GO:0043024 ribosomal small subunit binding 3/1020 20/18639 0.15 2.74102941176471 0.0931302841788302 0.410016033838844 GO:0031369 translation initiation factor binding 4/1020 32/18639 0.125 2.28419117647059 0.095265971322125 0.410016033838844 GO:0043425 bHLH transcription factor binding 4/1020 32/18639 0.125 2.28419117647059 0.095265971322125 0.410016033838844 GO:0047498 calcium-dependent phospholipase A2 activity 4/1020 32/18639 0.125 2.28419117647059 0.095265971322125 0.410016033838844 GO:0071813 lipoprotein particle binding 4/1020 32/18639 0.125 2.28419117647059 0.095265971322125 0.410016033838844 GO:0071814 protein-lipid complex binding 4/1020 32/18639 0.125 2.28419117647059 0.095265971322125 0.410016033838844 GO:0120015 sterol transfer activity 4/1020 32/18639 0.125 2.28419117647059 0.095265971322125 0.410016033838844 GO:0042605 peptide antigen binding 5/1020 45/18639 0.111111111111111 2.03039215686274 0.0979091035294284 0.410016033838844 GO:0003680 minor groove of adenine-thymine-rich DNA binding 2/1020 10/18639 0.2 3.65470588235294 0.100569970564245 0.410016033838844 GO:0004090 carbonyl reductase (NADPH) activity 2/1020 10/18639 0.2 3.65470588235294 0.100569970564245 0.410016033838844 GO:0004955 prostaglandin receptor activity 2/1020 10/18639 0.2 3.65470588235294 0.100569970564245 0.410016033838844 GO:0005345 purine nucleobase transmembrane transporter activity 2/1020 10/18639 0.2 3.65470588235294 0.100569970564245 0.410016033838844 GO:0005381 iron ion transmembrane transporter activity 2/1020 10/18639 0.2 3.65470588235294 0.100569970564245 0.410016033838844 GO:0008190 eukaryotic initiation factor 4E binding 2/1020 10/18639 0.2 3.65470588235294 0.100569970564245 0.410016033838844 GO:0016175 superoxide-generating NAD(P)H oxidase activity 2/1020 10/18639 0.2 3.65470588235294 0.100569970564245 0.410016033838844 GO:0016783 sulfurtransferase activity 2/1020 10/18639 0.2 3.65470588235294 0.100569970564245 0.410016033838844 GO:0030957 Tat protein binding 2/1020 10/18639 0.2 3.65470588235294 0.100569970564245 0.410016033838844 GO:0050815 phosphoserine residue binding 2/1020 10/18639 0.2 3.65470588235294 0.100569970564245 0.410016033838844 GO:0051880 G-quadruplex DNA binding 2/1020 10/18639 0.2 3.65470588235294 0.100569970564245 0.410016033838844 GO:0070513 death domain binding 2/1020 10/18639 0.2 3.65470588235294 0.100569970564245 0.410016033838844 GO:0098505 G-rich strand telomeric DNA binding 2/1020 10/18639 0.2 3.65470588235294 0.100569970564245 0.410016033838844 GO:0004866 endopeptidase inhibitor activity 13/1020 161/18639 0.0807453416149068 1.47550237486299 0.103802766309352 0.418980519827991 GO:0019956 chemokine binding 4/1020 33/18639 0.121212121212121 2.21497326203209 0.103958213927649 0.418980519827991 GO:0010314 phosphatidylinositol-5-phosphate binding 3/1020 21/18639 0.142857142857143 2.61050420168067 0.104433078924355 0.418980519827991 GO:0140312 cargo adaptor activity 3/1020 21/18639 0.142857142857143 2.61050420168067 0.104433078924355 0.418980519827991 GO:0031683 G-protein beta/gamma-subunit complex binding 3/1020 22/18639 0.136363636363636 2.4918449197861 0.116243240840768 0.454163641638457 GO:0070034 telomerase RNA binding 3/1020 22/18639 0.136363636363636 2.4918449197861 0.116243240840768 0.454163641638457 GO:0001851 complement component C3b binding 2/1020 11/18639 0.181818181818182 3.32245989304813 0.118614734608654 0.454163641638457 GO:0003953 NAD+ nucleosidase activity 2/1020 11/18639 0.181818181818182 3.32245989304813 0.118614734608654 0.454163641638457 GO:0004954 prostanoid receptor activity 2/1020 11/18639 0.181818181818182 3.32245989304813 0.118614734608654 0.454163641638457 GO:0008199 ferric iron binding 2/1020 11/18639 0.181818181818182 3.32245989304813 0.118614734608654 0.454163641638457 GO:0008503 benzodiazepine receptor activity 2/1020 11/18639 0.181818181818182 3.32245989304813 0.118614734608654 0.454163641638457 GO:0015205 nucleobase transmembrane transporter activity 2/1020 11/18639 0.181818181818182 3.32245989304813 0.118614734608654 0.454163641638457 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 2/1020 11/18639 0.181818181818182 3.32245989304813 0.118614734608654 0.454163641638457 GO:0032050 clathrin heavy chain binding 2/1020 11/18639 0.181818181818182 3.32245989304813 0.118614734608654 0.454163641638457 GO:0034713 type I transforming growth factor beta receptor binding 2/1020 11/18639 0.181818181818182 3.32245989304813 0.118614734608654 0.454163641638457 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/1020 11/18639 0.181818181818182 3.32245989304813 0.118614734608654 0.454163641638457 GO:0019210 kinase inhibitor activity 8/1020 90/18639 0.0888888888888889 1.6243137254902 0.119183408666858 0.454612471695175 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 5/1020 48/18639 0.104166666666667 1.90349264705882 0.120489390265323 0.457859683008228 GO:0017022 myosin binding 7/1020 76/18639 0.0921052631578947 1.68308823529412 0.121575193686153 0.460248947526152 GO:0004623 phospholipase A2 activity 4/1020 35/18639 0.114285714285714 2.08840336134454 0.122370295613765 0.461523923906596 GO:0016874 ligase activity 13/1020 167/18639 0.0778443113772455 1.42249031349067 0.127404406829634 0.477580873387429 GO:0000295 adenine nucleotide transmembrane transporter activity 3/1020 23/18639 0.130434782608696 2.38350383631714 0.128524743483608 0.477580873387429 GO:0017134 fibroblast growth factor binding 3/1020 23/18639 0.130434782608696 2.38350383631714 0.128524743483608 0.477580873387429 GO:0099186 structural constituent of postsynapse 3/1020 23/18639 0.130434782608696 2.38350383631714 0.128524743483608 0.477580873387429 GO:0004033 aldo-keto reductase (NADPH) activity 4/1020 36/18639 0.111111111111111 2.03039215686274 0.132061867849775 0.488920223987952 GO:0005496 steroid binding 9/1020 108/18639 0.0833333333333333 1.52279411764706 0.137053252677518 0.494074608001473 GO:0005095 GTPase inhibitor activity 2/1020 12/18639 0.166666666666667 3.04558823529412 0.137379235591273 0.494074608001473 GO:0008179 adenylate cyclase binding 2/1020 12/18639 0.166666666666667 3.04558823529412 0.137379235591273 0.494074608001473 GO:0015132 prostaglandin transmembrane transporter activity 2/1020 12/18639 0.166666666666667 3.04558823529412 0.137379235591273 0.494074608001473 GO:0043047 single-stranded telomeric DNA binding 2/1020 12/18639 0.166666666666667 3.04558823529412 0.137379235591273 0.494074608001473 GO:0070008 serine-type exopeptidase activity 2/1020 12/18639 0.166666666666667 3.04558823529412 0.137379235591273 0.494074608001473 GO:0070410 co-SMAD binding 2/1020 12/18639 0.166666666666667 3.04558823529412 0.137379235591273 0.494074608001473 GO:1990459 transferrin receptor binding 2/1020 12/18639 0.166666666666667 3.04558823529412 0.137379235591273 0.494074608001473 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 3/1020 24/18639 0.125 2.28419117647059 0.141241069929013 0.500809004994775 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 3/1020 24/18639 0.125 2.28419117647059 0.141241069929013 0.500809004994775 GO:0005540 hyaluronic acid binding 3/1020 24/18639 0.125 2.28419117647059 0.141241069929013 0.500809004994775 GO:0050431 transforming growth factor beta binding 3/1020 24/18639 0.125 2.28419117647059 0.141241069929013 0.500809004994775 GO:0005125 cytokine activity 17/1020 234/18639 0.0726495726495727 1.3275641025641 0.143216107843331 0.506030247713104 GO:0120013 lipid transfer activity 6/1020 65/18639 0.0923076923076923 1.68678733031674 0.144077120953132 0.507292520279036 GO:0005501 retinoid binding 4/1020 38/18639 0.105263157894737 1.92352941176471 0.152340116625986 0.526093243360334 GO:0019840 isoprenoid binding 4/1020 38/18639 0.105263157894737 1.92352941176471 0.152340116625986 0.526093243360334 GO:0003707 nuclear steroid receptor activity 3/1020 25/18639 0.12 2.19282352941176 0.154355532622515 0.526093243360334 GO:0005537 D-mannose binding 3/1020 25/18639 0.12 2.19282352941176 0.154355532622515 0.526093243360334 GO:0004896 cytokine receptor activity 8/1020 96/18639 0.0833333333333333 1.52279411764706 0.154906760859046 0.526093243360334 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 2/1020 13/18639 0.153846153846154 2.81131221719457 0.156730857009037 0.526093243360334 GO:0005338 nucleotide-sugar transmembrane transporter activity 2/1020 13/18639 0.153846153846154 2.81131221719457 0.156730857009037 0.526093243360334 GO:0008035 high-density lipoprotein particle binding 2/1020 13/18639 0.153846153846154 2.81131221719457 0.156730857009037 0.526093243360334 GO:0017154 semaphorin receptor activity 2/1020 13/18639 0.153846153846154 2.81131221719457 0.156730857009037 0.526093243360334 GO:0043560 insulin receptor substrate binding 2/1020 13/18639 0.153846153846154 2.81131221719457 0.156730857009037 0.526093243360334 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 2/1020 13/18639 0.153846153846154 2.81131221719457 0.156730857009037 0.526093243360334 GO:0045159 myosin II binding 2/1020 13/18639 0.153846153846154 2.81131221719457 0.156730857009037 0.526093243360334 GO:0071714 icosanoid transmembrane transporter activity 2/1020 13/18639 0.153846153846154 2.81131221719457 0.156730857009037 0.526093243360334 GO:0089720 caspase binding 2/1020 13/18639 0.153846153846154 2.81131221719457 0.156730857009037 0.526093243360334 GO:0004864 protein phosphatase inhibitor activity 5/1020 53/18639 0.0943396226415094 1.72391786903441 0.162887608213749 0.536062158097717 GO:0005544 calcium-dependent phospholipid binding 5/1020 53/18639 0.0943396226415094 1.72391786903441 0.162887608213749 0.536062158097717 GO:0016860 intramolecular oxidoreductase activity 5/1020 53/18639 0.0943396226415094 1.72391786903441 0.162887608213749 0.536062158097717 GO:1901505 carbohydrate derivative transmembrane transporter activity 5/1020 53/18639 0.0943396226415094 1.72391786903441 0.162887608213749 0.536062158097717 GO:0000217 DNA secondary structure binding 4/1020 39/18639 0.102564102564103 1.87420814479638 0.162894757078353 0.536062158097717 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 4/1020 39/18639 0.102564102564103 1.87420814479638 0.162894757078353 0.536062158097717 GO:0032934 sterol binding 6/1020 68/18639 0.0882352941176471 1.61237024221453 0.167324047881306 0.543428848873366 GO:0004112 cyclic-nucleotide phosphodiesterase activity 3/1020 26/18639 0.115384615384615 2.10848416289593 0.167831551141625 0.543428848873366 GO:0015216 purine nucleotide transmembrane transporter activity 3/1020 26/18639 0.115384615384615 2.10848416289593 0.167831551141625 0.543428848873366 GO:0050681 nuclear androgen receptor binding 3/1020 26/18639 0.115384615384615 2.10848416289593 0.167831551141625 0.543428848873366 GO:0070412 R-SMAD binding 3/1020 26/18639 0.115384615384615 2.10848416289593 0.167831551141625 0.543428848873366 GO:0015485 cholesterol binding 5/1020 54/18639 0.0925925925925926 1.69199346405229 0.172007006870372 0.550418457759663 GO:0017069 snRNA binding 5/1020 54/18639 0.0925925925925926 1.69199346405229 0.172007006870372 0.550418457759663 GO:0004177 aminopeptidase activity 4/1020 40/18639 0.1 1.82735294117647 0.173704373432688 0.550418457759663 GO:0015036 disulfide oxidoreductase activity 4/1020 40/18639 0.1 1.82735294117647 0.173704373432688 0.550418457759663 GO:0140662 ATP-dependent protein folding chaperone 4/1020 40/18639 0.1 1.82735294117647 0.173704373432688 0.550418457759663 GO:0005161 platelet-derived growth factor receptor binding 2/1020 14/18639 0.142857142857143 2.61050420168067 0.176549316639892 0.550418457759663 GO:0008494 translation activator activity 2/1020 14/18639 0.142857142857143 2.61050420168067 0.176549316639892 0.550418457759663 GO:0016530 metallochaperone activity 2/1020 14/18639 0.142857142857143 2.61050420168067 0.176549316639892 0.550418457759663 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 2/1020 14/18639 0.142857142857143 2.61050420168067 0.176549316639892 0.550418457759663 GO:0042813 Wnt receptor activity 2/1020 14/18639 0.142857142857143 2.61050420168067 0.176549316639892 0.550418457759663 GO:0071933 Arp2/3 complex binding 2/1020 14/18639 0.142857142857143 2.61050420168067 0.176549316639892 0.550418457759663 GO:1901612 cardiolipin binding 2/1020 14/18639 0.142857142857143 2.61050420168067 0.176549316639892 0.550418457759663 GO:0005319 lipid transporter activity 13/1020 178/18639 0.0730337078651685 1.33458360872439 0.177767116245052 0.552504586601135 GO:0140313 molecular sequestering activity 5/1020 55/18639 0.0909090909090909 1.66122994652406 0.181318067464864 0.557635128730091 GO:0008266 poly(U) RNA binding 3/1020 27/18639 0.111111111111111 2.03039215686274 0.181632891979613 0.557635128730091 GO:0008320 protein transmembrane transporter activity 3/1020 27/18639 0.111111111111111 2.03039215686274 0.181632891979613 0.557635128730091 GO:0023026 MHC class II protein complex binding 3/1020 27/18639 0.111111111111111 2.03039215686274 0.181632891979613 0.557635128730091 GO:0019212 phosphatase inhibitor activity 5/1020 56/18639 0.0892857142857143 1.63156512605042 0.190810980720578 0.584032393877271 GO:0046625 sphingolipid binding 3/1020 28/18639 0.107142857142857 1.9578781512605 0.195723874109848 0.587842124257678 GO:0008307 structural constituent of muscle 4/1020 42/18639 0.0952380952380952 1.74033613445378 0.196020785391376 0.587842124257678 GO:0004953 icosanoid receptor activity 2/1020 15/18639 0.133333333333333 2.43647058823529 0.196725715863791 0.587842124257678 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 2/1020 15/18639 0.133333333333333 2.43647058823529 0.196725715863791 0.587842124257678 GO:0016846 carbon-sulfur lyase activity 2/1020 15/18639 0.133333333333333 2.43647058823529 0.196725715863791 0.587842124257678 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 2/1020 15/18639 0.133333333333333 2.43647058823529 0.196725715863791 0.587842124257678 GO:0031005 filamin binding 2/1020 15/18639 0.133333333333333 2.43647058823529 0.196725715863791 0.587842124257678 GO:0050780 dopamine receptor binding 2/1020 15/18639 0.133333333333333 2.43647058823529 0.196725715863791 0.587842124257678 GO:0051087 protein-folding chaperone binding 10/1020 134/18639 0.0746268656716418 1.36369622475856 0.198850856997241 0.592434357976988 GO:0015932 nucleobase-containing compound transmembrane transporter activity 5/1020 57/18639 0.087719298245614 1.60294117647059 0.200475732214166 0.593992442907155 GO:0042379 chemokine receptor binding 6/1020 72/18639 0.0833333333333333 1.52279411764706 0.200553555698543 0.593992442907155 GO:0140104 molecular carrier activity 17/1020 249/18639 0.0682730923694779 1.24759036144578 0.205766315265848 0.607644221327591 GO:0016829 lyase activity 14/1020 200/18639 0.07 1.27914705882353 0.207185491443349 0.61004616924986 GO:0043539 protein serine/threonine kinase activator activity 6/1020 73/18639 0.0821917808219178 1.50193392425463 0.2092173244322 0.613159508914719 GO:0043236 laminin binding 3/1020 29/18639 0.103448275862069 1.89036511156187 0.210069543769194 0.613159508914719 GO:0051861 glycolipid binding 3/1020 29/18639 0.103448275862069 1.89036511156187 0.210069543769194 0.613159508914719 GO:0016722 oxidoreductase activity, acting on metal ions 2/1020 16/18639 0.125 2.28419117647059 0.217161655937427 0.624805107225682 GO:0017070 U6 snRNA binding 2/1020 16/18639 0.125 2.28419117647059 0.217161655937427 0.624805107225682 GO:0034450 ubiquitin-ubiquitin ligase activity 2/1020 16/18639 0.125 2.28419117647059 0.217161655937427 0.624805107225682 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/1020 16/18639 0.125 2.28419117647059 0.217161655937427 0.624805107225682 GO:0070411 I-SMAD binding 2/1020 16/18639 0.125 2.28419117647059 0.217161655937427 0.624805107225682 GO:0001046 core promoter sequence-specific DNA binding 4/1020 44/18639 0.0909090909090909 1.66122994652406 0.219152488909064 0.628390525668422 GO:0070063 RNA polymerase binding 5/1020 59/18639 0.0847457627118644 1.54860418743769 0.220279896286944 0.628390525668422 GO:0070888 E-box binding 5/1020 59/18639 0.0847457627118644 1.54860418743769 0.220279896286944 0.628390525668422 GO:0005506 iron ion binding 11/1020 154/18639 0.0714285714285714 1.30525210084034 0.223031143745866 0.631866682553894 GO:0008187 poly-pyrimidine tract binding 3/1020 30/18639 0.1 1.82735294117647 0.224635821603073 0.631866682553894 GO:0015215 nucleotide transmembrane transporter activity 3/1020 30/18639 0.1 1.82735294117647 0.224635821603073 0.631866682553894 GO:0031210 phosphatidylcholine binding 3/1020 30/18639 0.1 1.82735294117647 0.224635821603073 0.631866682553894 GO:0098918 structural constituent of synapse 3/1020 30/18639 0.1 1.82735294117647 0.224635821603073 0.631866682553894 GO:0004175 endopeptidase activity 26/1020 405/18639 0.0641975308641975 1.17311546840959 0.226123331312189 0.634279093680707 GO:0003714 transcription corepressor activity 14/1020 204/18639 0.0686274509803922 1.25406574394464 0.228073811157015 0.637973132875318 GO:0072341 modified amino acid binding 7/1020 91/18639 0.0769230769230769 1.40565610859729 0.230213221109095 0.642173722041159 GO:0004550 nucleoside diphosphate kinase activity 2/1020 17/18639 0.117647058823529 2.14982698961938 0.237768416752697 0.650632596929255 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 2/1020 17/18639 0.117647058823529 2.14982698961938 0.237768416752697 0.650632596929255 GO:0005092 GDP-dissociation inhibitor activity 2/1020 17/18639 0.117647058823529 2.14982698961938 0.237768416752697 0.650632596929255 GO:0015278 intracellularly gated calcium channel activity 2/1020 17/18639 0.117647058823529 2.14982698961938 0.237768416752697 0.650632596929255 GO:0015347 sodium-independent organic anion transmembrane transporter activity 2/1020 17/18639 0.117647058823529 2.14982698961938 0.237768416752697 0.650632596929255 GO:0019198 transmembrane receptor protein phosphatase activity 2/1020 17/18639 0.117647058823529 2.14982698961938 0.237768416752697 0.650632596929255 GO:0036041 long-chain fatty acid binding 2/1020 17/18639 0.117647058823529 2.14982698961938 0.237768416752697 0.650632596929255 GO:0003713 transcription coactivator activity 17/1020 256/18639 0.06640625 1.2134765625 0.238707555567289 0.651432272239186 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 5/1020 61/18639 0.0819672131147541 1.49783027965284 0.24064776956724 0.653186803111079 GO:0019905 syntaxin binding 5/1020 61/18639 0.0819672131147541 1.49783027965284 0.24064776956724 0.653186803111079 GO:0019902 phosphatase binding 13/1020 190/18639 0.068421052631579 1.25029411764706 0.241990549864491 0.655065816434254 GO:0004180 carboxypeptidase activity 4/1020 46/18639 0.0869565217391304 1.58900255754476 0.242962138843546 0.655932637574936 GO:0005516 calmodulin binding 14/1020 207/18639 0.0676328502415459 1.23589087809037 0.24428873553611 0.657750686323162 GO:0022884 macromolecule transmembrane transporter activity 3/1020 32/18639 0.09375 1.71314338235294 0.254298968530576 0.679511189066963 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 3/1020 32/18639 0.09375 1.71314338235294 0.254298968530576 0.679511189066963 GO:0004222 metalloendopeptidase activity 8/1020 110/18639 0.0727272727272727 1.32898395721925 0.254394953603024 0.679511189066963 GO:0000400 four-way junction DNA binding 2/1020 18/18639 0.111111111111111 2.03039215686274 0.258466193896882 0.679570384475615 GO:0015172 acidic amino acid transmembrane transporter activity 2/1020 18/18639 0.111111111111111 2.03039215686274 0.258466193896882 0.679570384475615 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 2/1020 18/18639 0.111111111111111 2.03039215686274 0.258466193896882 0.679570384475615 GO:0017075 syntaxin-1 binding 2/1020 18/18639 0.111111111111111 2.03039215686274 0.258466193896882 0.679570384475615 GO:0050811 GABA receptor binding 2/1020 18/18639 0.111111111111111 2.03039215686274 0.258466193896882 0.679570384475615 GO:1990381 ubiquitin-specific protease binding 2/1020 18/18639 0.111111111111111 2.03039215686274 0.258466193896882 0.679570384475615 GO:0005507 copper ion binding 5/1020 63/18639 0.0793650793650794 1.45028011204482 0.261495591442288 0.685744949433292 GO:0019903 protein phosphatase binding 10/1020 144/18639 0.0694444444444444 1.26899509803922 0.264131998641142 0.690859539302935 GO:0008236 serine-type peptidase activity 13/1020 194/18639 0.0670103092783505 1.22451485748939 0.265183702102198 0.691813440458325 GO:0032266 phosphatidylinositol-3-phosphate binding 4/1020 48/18639 0.0833333333333333 1.52279411764706 0.267314071300571 0.69556917260898 GO:0140311 protein sequestering activity 3/1020 33/18639 0.0909090909090909 1.66122994652406 0.269333043990869 0.697219473775848 GO:0140416 transcription regulator inhibitor activity 3/1020 33/18639 0.0909090909090909 1.66122994652406 0.269333043990869 0.697219473775848 GO:0042800 histone H3K4 methyltransferase activity 2/1020 19/18639 0.105263157894737 1.92352941176471 0.279183390102443 0.720865830341436 GO:0016798 hydrolase activity, acting on glycosyl bonds 9/1020 130/18639 0.0692307692307692 1.26509049773756 0.282074192340428 0.725912296530662 GO:0015101 organic cation transmembrane transporter activity 6/1020 81/18639 0.0740740740740741 1.35359477124183 0.282579563296941 0.725912296530662 GO:0015035 protein-disulfide reductase activity 3/1020 34/18639 0.0882352941176471 1.61237024221453 0.284462283705331 0.728889363082108 GO:0017171 serine hydrolase activity 13/1020 198/18639 0.0656565656565657 1.19977718360071 0.289103379173563 0.738901276212633 GO:0019209 kinase activator activity 10/1020 148/18639 0.0675675675675676 1.23469793322734 0.291999525781437 0.740858057567622 GO:0015605 organophosphate ester transmembrane transporter activity 4/1020 50/18639 0.08 1.46188235294118 0.292076116042051 0.740858057567622 GO:0048020 CCR chemokine receptor binding 4/1020 50/18639 0.08 1.46188235294118 0.292076116042051 0.740858057567622 GO:0035401 histone H3Y41 kinase activity 8/1020 115/18639 0.0695652173913043 1.27120204603581 0.294004653115524 0.742011743577276 GO:0140801 histone H2AXY142 kinase activity 8/1020 115/18639 0.0695652173913043 1.27120204603581 0.294004653115524 0.742011743577276 GO:0005179 hormone activity 9/1020 132/18639 0.0681818181818182 1.24592245989305 0.297072588001999 0.743731401796255 GO:0016229 steroid dehydrogenase activity 3/1020 35/18639 0.0857142857142857 1.5663025210084 0.299658407588916 0.743731401796255 GO:0001614 purinergic nucleotide receptor activity 2/1020 20/18639 0.1 1.82735294117647 0.299855957427289 0.743731401796255 GO:0005326 neurotransmitter transmembrane transporter activity 2/1020 20/18639 0.1 1.82735294117647 0.299855957427289 0.743731401796255 GO:0016004 phospholipase activator activity 2/1020 20/18639 0.1 1.82735294117647 0.299855957427289 0.743731401796255 GO:0016502 nucleotide receptor activity 2/1020 20/18639 0.1 1.82735294117647 0.299855957427289 0.743731401796255 GO:0140939 histone H4 methyltransferase activity 2/1020 20/18639 0.1 1.82735294117647 0.299855957427289 0.743731401796255 GO:0003712 transcription coregulator activity 30/1020 495/18639 0.0606060606060606 1.10748663101604 0.306953551692191 0.758890789710487 GO:0008237 metallopeptidase activity 12/1020 184/18639 0.0652173913043478 1.19175191815857 0.307475116387168 0.758890789710487 GO:0015291 secondary active transmembrane transporter activity 18/1020 287/18639 0.0627177700348432 1.146075015372 0.309076285060648 0.760977552704334 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/1020 36/18639 0.0833333333333333 1.52279411764706 0.314894456656111 0.762812705084139 GO:0005484 SNAP receptor activity 3/1020 36/18639 0.0833333333333333 1.52279411764706 0.314894456656111 0.762812705084139 GO:0045505 dynein intermediate chain binding 3/1020 36/18639 0.0833333333333333 1.52279411764706 0.314894456656111 0.762812705084139 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 3/1020 36/18639 0.0833333333333333 1.52279411764706 0.314894456656111 0.762812705084139 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 3/1020 36/18639 0.0833333333333333 1.52279411764706 0.314894456656111 0.762812705084139 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 3/1020 36/18639 0.0833333333333333 1.52279411764706 0.314894456656111 0.762812705084139 GO:0005080 protein kinase C binding 4/1020 52/18639 0.0769230769230769 1.40565610859729 0.317121080732098 0.762812705084139 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 4/1020 52/18639 0.0769230769230769 1.40565610859729 0.317121080732098 0.762812705084139 GO:0005261 monoatomic cation channel activity 21/1020 341/18639 0.06158357771261 1.12534931861308 0.319376417412946 0.762812705084139 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2/1020 21/18639 0.0952380952380952 1.74033613445378 0.320426786743387 0.762812705084139 GO:0008373 sialyltransferase activity 2/1020 21/18639 0.0952380952380952 1.74033613445378 0.320426786743387 0.762812705084139 GO:0009975 cyclase activity 2/1020 21/18639 0.0952380952380952 1.74033613445378 0.320426786743387 0.762812705084139 GO:0015125 bile acid transmembrane transporter activity 2/1020 21/18639 0.0952380952380952 1.74033613445378 0.320426786743387 0.762812705084139 GO:0070182 DNA polymerase binding 2/1020 21/18639 0.0952380952380952 1.74033613445378 0.320426786743387 0.762812705084139 GO:0005216 monoatomic ion channel activity 27/1020 448/18639 0.0602678571428571 1.10130646008403 0.329426774640116 0.780412741820782 GO:0023023 MHC protein complex binding 3/1020 37/18639 0.0810810810810811 1.48163751987281 0.330144814315445 0.780412741820782 GO:0042805 actinin binding 3/1020 37/18639 0.0810810810810811 1.48163751987281 0.330144814315445 0.780412741820782 GO:0016782 transferase activity, transferring sulphur-containing groups 5/1020 70/18639 0.0714285714285714 1.30525210084034 0.337044474757116 0.79485664187451 GO:0008081 phosphoric diester hydrolase activity 6/1020 87/18639 0.0689655172413793 1.26024340770791 0.340819854391887 0.801684252860792 GO:0003925 G protein activity 4/1020 54/18639 0.0740740740740741 1.35359477124183 0.342327933197756 0.801684252860792 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 4/1020 54/18639 0.0740740740740741 1.35359477124183 0.342327933197756 0.801684252860792 GO:0000146 microfilament motor activity 3/1020 38/18639 0.0789473684210526 1.44264705882353 0.345385216974541 0.805099336790192 GO:0042162 telomeric DNA binding 3/1020 38/18639 0.0789473684210526 1.44264705882353 0.345385216974541 0.805099336790192 GO:0140299 molecular sensor activity 5/1020 71/18639 0.0704225352112676 1.28686826843413 0.348030745124014 0.809392518105962 GO:0070851 growth factor receptor binding 9/1020 139/18639 0.0647482014388489 1.18317816335167 0.350895920911074 0.813897263196489 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 8/1020 122/18639 0.0655737704918033 1.19826422372228 0.351584219950817 0.813897263196489 GO:0004713 protein tyrosine kinase activity 9/1020 140/18639 0.0642857142857143 1.1747268907563 0.358708215379435 0.822609942367233 GO:0003727 single-stranded RNA binding 6/1020 89/18639 0.0674157303370786 1.2319233311302 0.360542379540878 0.822609942367233 GO:0016776 phosphotransferase activity, phosphate group as acceptor 3/1020 39/18639 0.0769230769230769 1.40565610859729 0.360592755299224 0.822609942367233 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 3/1020 39/18639 0.0769230769230769 1.40565610859729 0.360592755299224 0.822609942367233 GO:0000149 SNARE binding 7/1020 106/18639 0.0660377358490566 1.20674250832408 0.360653571314187 0.822609942367233 GO:0016849 phosphorus-oxygen lyase activity 2/1020 23/18639 0.0869565217391304 1.58900255754476 0.361066131605081 0.822609942367233 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 2/1020 23/18639 0.0869565217391304 1.58900255754476 0.361066131605081 0.822609942367233 GO:0170055 lipid transmembrane transporter activity 4/1020 56/18639 0.0714285714285714 1.30525210084034 0.367582710056547 0.835566115184972 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 3/1020 40/18639 0.075 1.37051470588235 0.375745867342457 0.845237186469747 GO:0050997 quaternary ammonium group binding 3/1020 40/18639 0.075 1.37051470588235 0.375745867342457 0.845237186469747 GO:0071855 neuropeptide receptor binding 3/1020 40/18639 0.075 1.37051470588235 0.375745867342457 0.845237186469747 GO:0099106 ion channel regulator activity 10/1020 160/18639 0.0625 1.14209558823529 0.379331893210135 0.845237186469747 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 6/1020 91/18639 0.0659340659340659 1.20484809308339 0.38032848552496 0.845237186469747 GO:0004622 lysophospholipase activity 2/1020 24/18639 0.0833333333333333 1.52279411764706 0.381050228121087 0.845237186469747 GO:0035035 histone acetyltransferase binding 2/1020 24/18639 0.0833333333333333 1.52279411764706 0.381050228121087 0.845237186469747 GO:0060229 lipase activator activity 2/1020 24/18639 0.0833333333333333 1.52279411764706 0.381050228121087 0.845237186469747 GO:0070300 phosphatidic acid binding 2/1020 24/18639 0.0833333333333333 1.52279411764706 0.381050228121087 0.845237186469747 GO:0070840 dynein complex binding 2/1020 24/18639 0.0833333333333333 1.52279411764706 0.381050228121087 0.845237186469747 GO:0031491 nucleosome binding 5/1020 74/18639 0.0675675675675676 1.23469793322734 0.381070191318039 0.845237186469747 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 3/1020 41/18639 0.0731707317073171 1.337087517934 0.390824324641753 0.859286193819381 GO:0140318 protein transporter activity 3/1020 41/18639 0.0731707317073171 1.337087517934 0.390824324641753 0.859286193819381 GO:0003725 double-stranded RNA binding 5/1020 75/18639 0.0666666666666667 1.21823529411765 0.392080554560119 0.859286193819381 GO:0061980 regulatory RNA binding 4/1020 58/18639 0.0689655172413793 1.26024340770791 0.392779180887432 0.859286193819381 GO:0016853 isomerase activity 11/1020 180/18639 0.0611111111111111 1.11671568627451 0.397544051735305 0.859286193819381 GO:0031490 chromatin DNA binding 8/1020 128/18639 0.0625 1.14209558823529 0.401935183760377 0.859286193819381 GO:0001786 phosphatidylserine binding 4/1020 59/18639 0.0677966101694915 1.23888334995015 0.405324583403832 0.859286193819381 GO:0004879 nuclear receptor activity 4/1020 59/18639 0.0677966101694915 1.23888334995015 0.405324583403832 0.859286193819381 GO:0045309 protein phosphorylated amino acid binding 4/1020 59/18639 0.0677966101694915 1.23888334995015 0.405324583403832 0.859286193819381 GO:0035198 miRNA binding 3/1020 42/18639 0.0714285714285714 1.30525210084034 0.405809212276397 0.859286193819381 GO:0098531 ligand-modulated transcription factor activity 4/1020 60/18639 0.0666666666666667 1.21823529411765 0.417819296938051 0.859286193819381 GO:0004867 serine-type endopeptidase inhibitor activity 6/1020 95/18639 0.0631578947368421 1.15411764705882 0.419886123294574 0.859286193819381 GO:0001637 G protein-coupled chemoattractant receptor activity 2/1020 26/18639 0.0769230769230769 1.40565610859729 0.420173748604749 0.859286193819381 GO:0004950 chemokine receptor activity 2/1020 26/18639 0.0769230769230769 1.40565610859729 0.420173748604749 0.859286193819381 GO:0008143 poly(A) binding 2/1020 26/18639 0.0769230769230769 1.40565610859729 0.420173748604749 0.859286193819381 GO:0070006 metalloaminopeptidase activity 2/1020 26/18639 0.0769230769230769 1.40565610859729 0.420173748604749 0.859286193819381 GO:0097602 cullin family protein binding 2/1020 26/18639 0.0769230769230769 1.40565610859729 0.420173748604749 0.859286193819381 GO:0120014 phospholipid transfer activity 2/1020 26/18639 0.0769230769230769 1.40565610859729 0.420173748604749 0.859286193819381 GO:0031072 heat shock protein binding 8/1020 131/18639 0.0610687022900763 1.11594072743601 0.427166109975625 0.859286193819381 GO:0000182 rDNA binding 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0001094 TFIID-class transcription factor complex binding 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0003796 lysozyme activity 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0005031 tumor necrosis factor receptor activity 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0005131 growth hormone receptor binding 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0005337 nucleoside transmembrane transporter activity 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0005522 profilin binding 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0015203 polyamine transmembrane transporter activity 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0016868 intramolecular phosphotransferase activity 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0019911 structural constituent of myelin sheath 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0032356 oxidized DNA binding 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0033204 ribonuclease P RNA binding 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0043121 neurotrophin binding 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0043208 glycosphingolipid binding 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0043295 glutathione binding 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0043422 protein kinase B binding 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0047429 nucleoside triphosphate diphosphatase activity 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0070097 delta-catenin binding 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0071723 lipopeptide binding 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0097177 mitochondrial ribosome binding 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0140999 histone H3K4 trimethyltransferase activity 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0141109 transporter activator activity 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:1905394 retromer complex binding 1/1020 10/18639 0.1 1.82735294117647 0.430458007250498 0.859286193819381 GO:0001223 transcription coactivator binding 3/1020 44/18639 0.0681818181818182 1.24592245989305 0.435429031694811 0.859286193819381 GO:0016790 thiolester hydrolase activity 3/1020 44/18639 0.0681818181818182 1.24592245989305 0.435429031694811 0.859286193819381 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 8/1020 132/18639 0.0606060606060606 1.10748663101604 0.435559240425536 0.859286193819381 GO:0016247 channel regulator activity 10/1020 168/18639 0.0595238095238095 1.08771008403361 0.43886256138585 0.859286193819381 GO:0005385 zinc ion transmembrane transporter activity 2/1020 27/18639 0.0740740740740741 1.35359477124183 0.43925701713476 0.859286193819381 GO:0016405 CoA-ligase activity 2/1020 27/18639 0.0740740740740741 1.35359477124183 0.43925701713476 0.859286193819381 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 2/1020 27/18639 0.0740740740740741 1.35359477124183 0.43925701713476 0.859286193819381 GO:0015179 L-amino acid transmembrane transporter activity 4/1020 62/18639 0.0645161290322581 1.17893738140417 0.442613452443721 0.859286193819381 GO:0000049 tRNA binding 5/1020 80/18639 0.0625 1.14209558823529 0.446739358248099 0.859286193819381 GO:0008234 cysteine-type peptidase activity 11/1020 187/18639 0.0588235294117647 1.07491349480969 0.447046186571614 0.859286193819381 GO:0141108 transporter regulator activity 10/1020 170/18639 0.0588235294117647 1.07491349480969 0.453709982876412 0.859286193819381 GO:0001217 DNA-binding transcription repressor activity 16/1020 278/18639 0.0575539568345324 1.05171392297926 0.454465119562357 0.859286193819381 GO:0045499 chemorepellent activity 2/1020 28/18639 0.0714285714285714 1.30525210084034 0.457990335828984 0.859286193819381 GO:0050698 proteoglycan sulfotransferase activity 2/1020 28/18639 0.0714285714285714 1.30525210084034 0.457990335828984 0.859286193819381 GO:0051019 mitogen-activated protein kinase binding 2/1020 28/18639 0.0714285714285714 1.30525210084034 0.457990335828984 0.859286193819381 GO:0051537 2 iron, 2 sulfur cluster binding 2/1020 28/18639 0.0714285714285714 1.30525210084034 0.457990335828984 0.859286193819381 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 2/1020 28/18639 0.0714285714285714 1.30525210084034 0.457990335828984 0.859286193819381 GO:1990782 protein tyrosine kinase binding 7/1020 117/18639 0.0598290598290598 1.09328808446456 0.4600605109169 0.859286193819381 GO:0015297 antiporter activity 8/1020 135/18639 0.0592592592592593 1.08287581699346 0.460636789592848 0.859286193819381 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/1020 11/18639 0.0909090909090909 1.66122994652406 0.461642334514682 0.859286193819381 GO:0004016 adenylate cyclase activity 1/1020 11/18639 0.0909090909090909 1.66122994652406 0.461642334514682 0.859286193819381 GO:0005114 type II transforming growth factor beta receptor binding 1/1020 11/18639 0.0909090909090909 1.66122994652406 0.461642334514682 0.859286193819381 GO:0008172 S-methyltransferase activity 1/1020 11/18639 0.0909090909090909 1.66122994652406 0.461642334514682 0.859286193819381 GO:0008432 JUN kinase binding 1/1020 11/18639 0.0909090909090909 1.66122994652406 0.461642334514682 0.859286193819381 GO:0008526 phosphatidylinositol transfer activity 1/1020 11/18639 0.0909090909090909 1.66122994652406 0.461642334514682 0.859286193819381 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 1/1020 11/18639 0.0909090909090909 1.66122994652406 0.461642334514682 0.859286193819381 GO:0015173 aromatic amino acid transmembrane transporter activity 1/1020 11/18639 0.0909090909090909 1.66122994652406 0.461642334514682 0.859286193819381 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/1020 11/18639 0.0909090909090909 1.66122994652406 0.461642334514682 0.859286193819381 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/1020 11/18639 0.0909090909090909 1.66122994652406 0.461642334514682 0.859286193819381 GO:0019215 intermediate filament binding 1/1020 11/18639 0.0909090909090909 1.66122994652406 0.461642334514682 0.859286193819381 GO:0034056 estrogen response element binding 1/1020 11/18639 0.0909090909090909 1.66122994652406 0.461642334514682 0.859286193819381 GO:0034511 U3 snoRNA binding 1/1020 11/18639 0.0909090909090909 1.66122994652406 0.461642334514682 0.859286193819381 GO:0035252 UDP-xylosyltransferase activity 1/1020 11/18639 0.0909090909090909 1.66122994652406 0.461642334514682 0.859286193819381 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/1020 11/18639 0.0909090909090909 1.66122994652406 0.461642334514682 0.859286193819381 GO:0042285 xylosyltransferase activity 1/1020 11/18639 0.0909090909090909 1.66122994652406 0.461642334514682 0.859286193819381 GO:0045294 alpha-catenin binding 1/1020 11/18639 0.0909090909090909 1.66122994652406 0.461642334514682 0.859286193819381 GO:0048185 activin binding 1/1020 11/18639 0.0909090909090909 1.66122994652406 0.461642334514682 0.859286193819381 GO:0050998 nitric-oxide synthase binding 1/1020 11/18639 0.0909090909090909 1.66122994652406 0.461642334514682 0.859286193819381 GO:0070697 activin receptor binding 1/1020 11/18639 0.0909090909090909 1.66122994652406 0.461642334514682 0.859286193819381 GO:0180030 inositol phosphate kinase activity 1/1020 11/18639 0.0909090909090909 1.66122994652406 0.461642334514682 0.859286193819381 GO:1900750 oligopeptide binding 1/1020 11/18639 0.0909090909090909 1.66122994652406 0.461642334514682 0.859286193819381 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 3/1020 46/18639 0.0652173913043478 1.19175191815857 0.464479220750557 0.861382274946246 GO:0030291 protein serine/threonine kinase inhibitor activity 3/1020 46/18639 0.0652173913043478 1.19175191815857 0.464479220750557 0.861382274946246 GO:0030246 carbohydrate binding 16/1020 280/18639 0.0571428571428571 1.04420168067227 0.466055469213543 0.862716649812569 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 2/1020 29/18639 0.0689655172413793 1.26024340770791 0.476354838944524 0.868752377200541 GO:0099604 ligand-gated calcium channel activity 2/1020 29/18639 0.0689655172413793 1.26024340770791 0.476354838944524 0.868752377200541 GO:0005254 chloride channel activity 5/1020 83/18639 0.0602409638554217 1.1008150248051 0.478951855930066 0.868752377200541 GO:0051117 ATPase binding 5/1020 84/18639 0.0595238095238095 1.08771008403361 0.489551756076526 0.868752377200541 GO:0004032 aldose reductase (NADPH) activity 1/1020 12/18639 0.0833333333333333 1.52279411764706 0.491120798053174 0.868752377200541 GO:0004526 ribonuclease P activity 1/1020 12/18639 0.0833333333333333 1.52279411764706 0.491120798053174 0.868752377200541 GO:0005049 nuclear export signal receptor activity 1/1020 12/18639 0.0833333333333333 1.52279411764706 0.491120798053174 0.868752377200541 GO:0005165 neurotrophin receptor binding 1/1020 12/18639 0.0833333333333333 1.52279411764706 0.491120798053174 0.868752377200541 GO:0005247 voltage-gated chloride channel activity 1/1020 12/18639 0.0833333333333333 1.52279411764706 0.491120798053174 0.868752377200541 GO:0008504 monoamine transmembrane transporter activity 1/1020 12/18639 0.0833333333333333 1.52279411764706 0.491120798053174 0.868752377200541 GO:0015368 calcium:monoatomic cation antiporter activity 1/1020 12/18639 0.0833333333333333 1.52279411764706 0.491120798053174 0.868752377200541 GO:0016208 AMP binding 1/1020 12/18639 0.0833333333333333 1.52279411764706 0.491120798053174 0.868752377200541 GO:0031543 peptidyl-proline dioxygenase activity 1/1020 12/18639 0.0833333333333333 1.52279411764706 0.491120798053174 0.868752377200541 GO:0034452 dynactin binding 1/1020 12/18639 0.0833333333333333 1.52279411764706 0.491120798053174 0.868752377200541 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/1020 12/18639 0.0833333333333333 1.52279411764706 0.491120798053174 0.868752377200541 GO:0035197 siRNA binding 1/1020 12/18639 0.0833333333333333 1.52279411764706 0.491120798053174 0.868752377200541 GO:0042301 phosphate ion binding 1/1020 12/18639 0.0833333333333333 1.52279411764706 0.491120798053174 0.868752377200541 GO:0045295 gamma-catenin binding 1/1020 12/18639 0.0833333333333333 1.52279411764706 0.491120798053174 0.868752377200541 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/1020 12/18639 0.0833333333333333 1.52279411764706 0.491120798053174 0.868752377200541 GO:0070679 inositol 1,4,5 trisphosphate binding 1/1020 12/18639 0.0833333333333333 1.52279411764706 0.491120798053174 0.868752377200541 GO:0097677 STAT family protein binding 1/1020 12/18639 0.0833333333333333 1.52279411764706 0.491120798053174 0.868752377200541 GO:1990817 poly(A) RNA polymerase activity 1/1020 12/18639 0.0833333333333333 1.52279411764706 0.491120798053174 0.868752377200541 GO:0008235 metalloexopeptidase activity 4/1020 66/18639 0.0606060606060606 1.10748663101604 0.491148141268361 0.868752377200541 GO:0030295 protein kinase activator activity 8/1020 139/18639 0.0575539568345324 1.05171392297926 0.493709604374177 0.868752377200541 GO:0001965 G-protein alpha-subunit binding 2/1020 30/18639 0.0666666666666667 1.21823529411765 0.494334768754628 0.868752377200541 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 2/1020 30/18639 0.0666666666666667 1.21823529411765 0.494334768754628 0.868752377200541 GO:0016769 transferase activity, transferring nitrogenous groups 2/1020 30/18639 0.0666666666666667 1.21823529411765 0.494334768754628 0.868752377200541 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/1020 30/18639 0.0666666666666667 1.21823529411765 0.494334768754628 0.868752377200541 GO:0070566 adenylyltransferase activity 2/1020 30/18639 0.0666666666666667 1.21823529411765 0.494334768754628 0.868752377200541 GO:0004252 serine-type endopeptidase activity 10/1020 176/18639 0.0568181818181818 1.03826871657754 0.497848697825476 0.873403551760025 GO:0016763 pentosyltransferase activity 3/1020 49/18639 0.0612244897959184 1.118787515006 0.506757093093633 0.87687841083697 GO:0060590 ATPase regulator activity 3/1020 49/18639 0.0612244897959184 1.118787515006 0.506757093093633 0.87687841083697 GO:0008514 organic anion transmembrane transporter activity 15/1020 269/18639 0.0557620817843866 1.01897004154822 0.508128915108124 0.87687841083697 GO:0005184 neuropeptide hormone activity 2/1020 31/18639 0.0645161290322581 1.17893738140417 0.511917192458927 0.87687841083697 GO:0016878 acid-thiol ligase activity 2/1020 31/18639 0.0645161290322581 1.17893738140417 0.511917192458927 0.87687841083697 GO:0070273 phosphatidylinositol-4-phosphate binding 2/1020 31/18639 0.0645161290322581 1.17893738140417 0.511917192458927 0.87687841083697 GO:0072349 modified amino acid transmembrane transporter activity 2/1020 31/18639 0.0645161290322581 1.17893738140417 0.511917192458927 0.87687841083697 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/1020 13/18639 0.0769230769230769 1.40565610859729 0.518986626473519 0.87687841083697 GO:0005035 death receptor activity 1/1020 13/18639 0.0769230769230769 1.40565610859729 0.518986626473519 0.87687841083697 GO:0005542 folic acid binding 1/1020 13/18639 0.0769230769230769 1.40565610859729 0.518986626473519 0.87687841083697 GO:0008253 5'-nucleotidase activity 1/1020 13/18639 0.0769230769230769 1.40565610859729 0.518986626473519 0.87687841083697 GO:0008417 fucosyltransferase activity 1/1020 13/18639 0.0769230769230769 1.40565610859729 0.518986626473519 0.87687841083697 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/1020 13/18639 0.0769230769230769 1.40565610859729 0.518986626473519 0.87687841083697 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/1020 13/18639 0.0769230769230769 1.40565610859729 0.518986626473519 0.87687841083697 GO:0031994 insulin-like growth factor I binding 1/1020 13/18639 0.0769230769230769 1.40565610859729 0.518986626473519 0.87687841083697 GO:0032396 inhibitory MHC class I receptor activity 1/1020 13/18639 0.0769230769230769 1.40565610859729 0.518986626473519 0.87687841083697 GO:0035673 oligopeptide transmembrane transporter activity 1/1020 13/18639 0.0769230769230769 1.40565610859729 0.518986626473519 0.87687841083697 GO:0039706 co-receptor binding 1/1020 13/18639 0.0769230769230769 1.40565610859729 0.518986626473519 0.87687841083697 GO:0046975 histone H3K36 methyltransferase activity 1/1020 13/18639 0.0769230769230769 1.40565610859729 0.518986626473519 0.87687841083697 GO:0071837 HMG box domain binding 1/1020 13/18639 0.0769230769230769 1.40565610859729 0.518986626473519 0.87687841083697 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/1020 13/18639 0.0769230769230769 1.40565610859729 0.518986626473519 0.87687841083697 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/1020 13/18639 0.0769230769230769 1.40565610859729 0.518986626473519 0.87687841083697 GO:0008013 beta-catenin binding 6/1020 106/18639 0.0566037735849057 1.03435072142064 0.52590845975553 0.886514780209423 GO:0030515 snoRNA binding 2/1020 32/18639 0.0625 1.14209558823529 0.529091740720817 0.886514780209423 GO:0051059 NF-kappaB binding 2/1020 32/18639 0.0625 1.14209558823529 0.529091740720817 0.886514780209423 GO:0070717 poly-purine tract binding 2/1020 32/18639 0.0625 1.14209558823529 0.529091740720817 0.886514780209423 GO:0160041 neuropeptide activity 2/1020 32/18639 0.0625 1.14209558823529 0.529091740720817 0.886514780209423 GO:0005272 sodium channel activity 3/1020 51/18639 0.0588235294117647 1.07491349480969 0.533953207931143 0.889435791068789 GO:0016830 carbon-carbon lyase activity 3/1020 51/18639 0.0588235294117647 1.07491349480969 0.533953207931143 0.889435791068789 GO:0004065 arylsulfatase activity 1/1020 14/18639 0.0714285714285714 1.30525210084034 0.545327957999183 0.889435791068789 GO:0008195 phosphatidate phosphatase activity 1/1020 14/18639 0.0714285714285714 1.30525210084034 0.545327957999183 0.889435791068789 GO:0008474 palmitoyl-(protein) hydrolase activity 1/1020 14/18639 0.0714285714285714 1.30525210084034 0.545327957999183 0.889435791068789 GO:0008559 ABC-type xenobiotic transporter activity 1/1020 14/18639 0.0714285714285714 1.30525210084034 0.545327957999183 0.889435791068789 GO:0015386 potassium:proton antiporter activity 1/1020 14/18639 0.0714285714285714 1.30525210084034 0.545327957999183 0.889435791068789 GO:0019992 diacylglycerol binding 1/1020 14/18639 0.0714285714285714 1.30525210084034 0.545327957999183 0.889435791068789 GO:0031404 chloride ion binding 1/1020 14/18639 0.0714285714285714 1.30525210084034 0.545327957999183 0.889435791068789 GO:0042043 neurexin family protein binding 1/1020 14/18639 0.0714285714285714 1.30525210084034 0.545327957999183 0.889435791068789 GO:0061783 peptidoglycan muralytic activity 1/1020 14/18639 0.0714285714285714 1.30525210084034 0.545327957999183 0.889435791068789 GO:0070742 C2H2 zinc finger domain binding 1/1020 14/18639 0.0714285714285714 1.30525210084034 0.545327957999183 0.889435791068789 GO:0098599 palmitoyl hydrolase activity 1/1020 14/18639 0.0714285714285714 1.30525210084034 0.545327957999183 0.889435791068789 GO:1901474 azole transmembrane transporter activity 1/1020 14/18639 0.0714285714285714 1.30525210084034 0.545327957999183 0.889435791068789 GO:1990825 sequence-specific mRNA binding 1/1020 14/18639 0.0714285714285714 1.30525210084034 0.545327957999183 0.889435791068789 GO:0003924 GTPase activity 18/1020 331/18639 0.054380664652568 0.993726674960014 0.545790182494205 0.889435791068789 GO:0030296 protein tyrosine kinase activator activity 2/1020 33/18639 0.0606060606060606 1.10748663101604 0.545850366316298 0.889435791068789 GO:0042826 histone deacetylase binding 7/1020 127/18639 0.0551181102362205 1.00720240852246 0.547300289745024 0.8903576603768 GO:0004620 phospholipase activity 6/1020 109/18639 0.055045871559633 1.00588235294118 0.553511666641569 0.899010077916226 GO:0005246 calcium channel regulator activity 3/1020 53/18639 0.0566037735849057 1.03435072142064 0.560279668850607 0.902861187073542 GO:0008146 sulfotransferase activity 3/1020 53/18639 0.0566037735849057 1.03435072142064 0.560279668850607 0.902861187073542 GO:0140296 general transcription initiation factor binding 3/1020 53/18639 0.0566037735849057 1.03435072142064 0.560279668850607 0.902861187073542 GO:0016831 carboxy-lyase activity 2/1020 34/18639 0.0588235294117647 1.07491349480969 0.562187121479483 0.902861187073542 GO:0051427 hormone receptor binding 2/1020 34/18639 0.0588235294117647 1.07491349480969 0.562187121479483 0.902861187073542 GO:0000774 adenyl-nucleotide exchange factor activity 1/1020 15/18639 0.0666666666666667 1.21823529411765 0.570228118151711 0.902861187073542 GO:0004089 carbonate dehydratase activity 1/1020 15/18639 0.0666666666666667 1.21823529411765 0.570228118151711 0.902861187073542 GO:0004559 alpha-mannosidase activity 1/1020 15/18639 0.0666666666666667 1.21823529411765 0.570228118151711 0.902861187073542 GO:0008242 omega peptidase activity 1/1020 15/18639 0.0666666666666667 1.21823529411765 0.570228118151711 0.902861187073542 GO:0008252 nucleotidase activity 1/1020 15/18639 0.0666666666666667 1.21823529411765 0.570228118151711 0.902861187073542 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/1020 15/18639 0.0666666666666667 1.21823529411765 0.570228118151711 0.902861187073542 GO:0017081 chloride channel regulator activity 1/1020 15/18639 0.0666666666666667 1.21823529411765 0.570228118151711 0.902861187073542 GO:0033130 acetylcholine receptor binding 1/1020 15/18639 0.0666666666666667 1.21823529411765 0.570228118151711 0.902861187073542 GO:0034483 heparan sulfate sulfotransferase activity 1/1020 15/18639 0.0666666666666667 1.21823529411765 0.570228118151711 0.902861187073542 GO:0042809 nuclear vitamin D receptor binding 1/1020 15/18639 0.0666666666666667 1.21823529411765 0.570228118151711 0.902861187073542 GO:0140161 monocarboxylate:sodium symporter activity 1/1020 15/18639 0.0666666666666667 1.21823529411765 0.570228118151711 0.902861187073542 GO:0050661 NADP binding 3/1020 54/18639 0.0555555555555556 1.01519607843137 0.573100359183128 0.905984398269089 GO:0003730 mRNA 3'-UTR binding 14/1020 262/18639 0.0534351145038168 0.976448136506511 0.575735918134034 0.908724246960771 GO:0005343 organic acid:sodium symporter activity 2/1020 35/18639 0.0571428571428571 1.04420168067227 0.578097952624366 0.911024473071576 GO:0051213 dioxygenase activity 5/1020 93/18639 0.0537634408602151 0.982447817836812 0.580793115369828 0.912416017437467 GO:0051219 phosphoprotein binding 5/1020 93/18639 0.0537634408602151 0.982447817836812 0.580793115369828 0.912416017437467 GO:0048029 monosaccharide binding 4/1020 74/18639 0.0540540540540541 0.987758346581876 0.582258570834992 0.913293428085416 GO:0008374 O-acyltransferase activity 3/1020 55/18639 0.0545454545454545 0.996737967914438 0.58568560156132 0.915654277910299 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/1020 36/18639 0.0555555555555556 1.01519607843137 0.593580511210734 0.915654277910299 GO:0000062 fatty-acyl-CoA binding 1/1020 16/18639 0.0625 1.14209558823529 0.59376588229933 0.915654277910299 GO:0005024 transforming growth factor beta receptor activity 1/1020 16/18639 0.0625 1.14209558823529 0.59376588229933 0.915654277910299 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/1020 16/18639 0.0625 1.14209558823529 0.59376588229933 0.915654277910299 GO:0005521 lamin binding 1/1020 16/18639 0.0625 1.14209558823529 0.59376588229933 0.915654277910299 GO:0015385 sodium:proton antiporter activity 1/1020 16/18639 0.0625 1.14209558823529 0.59376588229933 0.915654277910299 GO:0015562 efflux transmembrane transporter activity 1/1020 16/18639 0.0625 1.14209558823529 0.59376588229933 0.915654277910299 GO:0015923 mannosidase activity 1/1020 16/18639 0.0625 1.14209558823529 0.59376588229933 0.915654277910299 GO:0022841 potassium ion leak channel activity 1/1020 16/18639 0.0625 1.14209558823529 0.59376588229933 0.915654277910299 GO:0022858 alanine transmembrane transporter activity 1/1020 16/18639 0.0625 1.14209558823529 0.59376588229933 0.915654277910299 GO:0001221 transcription coregulator binding 6/1020 115/18639 0.0521739130434783 0.953401534526854 0.606356570735881 0.928634481980937 GO:0022829 wide pore channel activity 2/1020 37/18639 0.0540540540540541 0.987758346581876 0.608633979604751 0.928634481980937 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 14/1020 268/18639 0.0522388059701493 0.954587357330992 0.610059529054661 0.928634481980937 GO:0051540 metal cluster binding 4/1020 77/18639 0.051948051948052 0.949274255156608 0.613904955436671 0.928634481980937 GO:0004549 tRNA-specific ribonuclease activity 1/1020 17/18639 0.0588235294117647 1.07491349480969 0.616015723895994 0.928634481980937 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/1020 17/18639 0.0588235294117647 1.07491349480969 0.616015723895994 0.928634481980937 GO:0008484 sulfuric ester hydrolase activity 1/1020 17/18639 0.0588235294117647 1.07491349480969 0.616015723895994 0.928634481980937 GO:0016805 dipeptidase activity 1/1020 17/18639 0.0588235294117647 1.07491349480969 0.616015723895994 0.928634481980937 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/1020 17/18639 0.0588235294117647 1.07491349480969 0.616015723895994 0.928634481980937 GO:0030548 acetylcholine receptor regulator activity 1/1020 17/18639 0.0588235294117647 1.07491349480969 0.616015723895994 0.928634481980937 GO:0032977 membrane insertase activity 1/1020 17/18639 0.0588235294117647 1.07491349480969 0.616015723895994 0.928634481980937 GO:0045236 CXCR chemokine receptor binding 1/1020 17/18639 0.0588235294117647 1.07491349480969 0.616015723895994 0.928634481980937 GO:0051787 misfolded protein binding 1/1020 17/18639 0.0588235294117647 1.07491349480969 0.616015723895994 0.928634481980937 GO:1901567 fatty acid derivative binding 1/1020 17/18639 0.0588235294117647 1.07491349480969 0.616015723895994 0.928634481980937 GO:1990226 histone methyltransferase binding 1/1020 17/18639 0.0588235294117647 1.07491349480969 0.616015723895994 0.928634481980937 GO:0140789 histone phosphatase activity 7/1020 136/18639 0.0514705882352941 0.940549307958477 0.620289874912479 0.933679976138814 GO:0043531 ADP binding 2/1020 38/18639 0.0526315789473684 0.961764705882353 0.623258910861985 0.936289878003714 GO:0004721 phosphoprotein phosphatase activity 9/1020 175/18639 0.0514285714285714 0.939781512605042 0.623883324866427 0.936289878003714 GO:0008170 N-methyltransferase activity 5/1020 98/18639 0.0510204081632653 0.932322929171669 0.627517129263714 0.937876294640921 GO:0015459 potassium channel regulator activity 3/1020 59/18639 0.0508474576271186 0.929162512462612 0.633595751020141 0.937876294640921 GO:0016835 carbon-oxygen lyase activity 4/1020 79/18639 0.0506329113924051 0.92524199553239 0.634155797378174 0.937876294640921 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 1/1020 18/18639 0.0555555555555556 1.01519607843137 0.63704804919006 0.937876294640921 GO:0008308 voltage-gated monoatomic anion channel activity 1/1020 18/18639 0.0555555555555556 1.01519607843137 0.63704804919006 0.937876294640921 GO:0008409 5'-3' exonuclease activity 1/1020 18/18639 0.0555555555555556 1.01519607843137 0.63704804919006 0.937876294640921 GO:0008525 phosphatidylcholine transporter activity 1/1020 18/18639 0.0555555555555556 1.01519607843137 0.63704804919006 0.937876294640921 GO:0015280 ligand-gated sodium channel activity 1/1020 18/18639 0.0555555555555556 1.01519607843137 0.63704804919006 0.937876294640921 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/1020 18/18639 0.0555555555555556 1.01519607843137 0.63704804919006 0.937876294640921 GO:0022851 GABA-gated chloride ion channel activity 1/1020 18/18639 0.0555555555555556 1.01519607843137 0.63704804919006 0.937876294640921 GO:0032393 MHC class I receptor activity 1/1020 18/18639 0.0555555555555556 1.01519607843137 0.63704804919006 0.937876294640921 GO:0034185 apolipoprotein binding 1/1020 18/18639 0.0555555555555556 1.01519607843137 0.63704804919006 0.937876294640921 GO:0099602 neurotransmitter receptor regulator activity 1/1020 18/18639 0.0555555555555556 1.01519607843137 0.63704804919006 0.937876294640921 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 25/1020 484/18639 0.0516528925619835 0.943880651434127 0.647258275885874 0.93967034811555 GO:0030971 receptor tyrosine kinase binding 4/1020 81/18639 0.0493827160493827 0.90239651416122 0.65370711793092 0.93967034811555 GO:0008017 microtubule binding 14/1020 276/18639 0.0507246376811594 0.926918158567775 0.653726539874103 0.93967034811555 GO:0015026 coreceptor activity 3/1020 61/18639 0.0491803278688525 0.898698167791707 0.656057579942286 0.93967034811555 GO:0003756 protein disulfide isomerase activity 1/1020 19/18639 0.0526315789473684 0.961764705882353 0.656929419139372 0.93967034811555 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/1020 19/18639 0.0526315789473684 0.961764705882353 0.656929419139372 0.93967034811555 GO:0004890 GABA-A receptor activity 1/1020 19/18639 0.0526315789473684 0.961764705882353 0.656929419139372 0.93967034811555 GO:0005520 insulin-like growth factor binding 1/1020 19/18639 0.0526315789473684 0.961764705882353 0.656929419139372 0.93967034811555 GO:0008574 plus-end-directed microtubule motor activity 1/1020 19/18639 0.0526315789473684 0.961764705882353 0.656929419139372 0.93967034811555 GO:0015245 fatty acid transmembrane transporter activity 1/1020 19/18639 0.0526315789473684 0.961764705882353 0.656929419139372 0.93967034811555 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/1020 19/18639 0.0526315789473684 0.961764705882353 0.656929419139372 0.93967034811555 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/1020 19/18639 0.0526315789473684 0.961764705882353 0.656929419139372 0.93967034811555 GO:0022821 solute:potassium antiporter activity 1/1020 19/18639 0.0526315789473684 0.961764705882353 0.656929419139372 0.93967034811555 GO:0022840 leak channel activity 1/1020 19/18639 0.0526315789473684 0.961764705882353 0.656929419139372 0.93967034811555 GO:0022842 narrow pore channel activity 1/1020 19/18639 0.0526315789473684 0.961764705882353 0.656929419139372 0.93967034811555 GO:0030506 ankyrin binding 1/1020 19/18639 0.0526315789473684 0.961764705882353 0.656929419139372 0.93967034811555 GO:0042577 lipid phosphatase activity 1/1020 19/18639 0.0526315789473684 0.961764705882353 0.656929419139372 0.93967034811555 GO:0046624 sphingolipid transporter activity 1/1020 19/18639 0.0526315789473684 0.961764705882353 0.656929419139372 0.93967034811555 GO:0070003 threonine-type peptidase activity 1/1020 19/18639 0.0526315789473684 0.961764705882353 0.656929419139372 0.93967034811555 GO:0120227 acyl-CoA binding 1/1020 19/18639 0.0526315789473684 0.961764705882353 0.656929419139372 0.93967034811555 GO:0015171 amino acid transmembrane transporter activity 5/1020 102/18639 0.0490196078431373 0.89576124567474 0.662539556833037 0.943917717243938 GO:0015175 neutral L-amino acid transmembrane transporter activity 2/1020 41/18639 0.0487804878048781 0.891391678622669 0.664585562587837 0.943917717243938 GO:0016877 ligase activity, forming carbon-sulfur bonds 2/1020 41/18639 0.0487804878048781 0.891391678622669 0.664585562587837 0.943917717243938 GO:0017080 sodium channel regulator activity 2/1020 41/18639 0.0487804878048781 0.891391678622669 0.664585562587837 0.943917717243938 GO:0140828 metal cation:monoatomic cation antiporter activity 2/1020 41/18639 0.0487804878048781 0.891391678622669 0.664585562587837 0.943917717243938 GO:0005253 monoatomic anion channel activity 5/1020 103/18639 0.0485436893203883 0.887064534551685 0.670952806411379 0.947593126061296 GO:0060589 nucleoside-triphosphatase regulator activity 25/1020 490/18639 0.0510204081632653 0.932322929171669 0.671247096945322 0.947593126061296 GO:0001216 DNA-binding transcription activator activity 25/1020 491/18639 0.0509164969450102 0.930424104468671 0.675162190719867 0.947593126061296 GO:0000339 RNA cap binding 1/1020 20/18639 0.05 0.913676470588235 0.675722759229481 0.947593126061296 GO:0001972 retinoic acid binding 1/1020 20/18639 0.05 0.913676470588235 0.675722759229481 0.947593126061296 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/1020 20/18639 0.05 0.913676470588235 0.675722759229481 0.947593126061296 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/1020 20/18639 0.05 0.913676470588235 0.675722759229481 0.947593126061296 GO:0016408 C-acyltransferase activity 1/1020 20/18639 0.05 0.913676470588235 0.675722759229481 0.947593126061296 GO:0019894 kinesin binding 2/1020 42/18639 0.0476190476190476 0.870168067226891 0.677524380103409 0.947593126061296 GO:0043175 RNA polymerase core enzyme binding 2/1020 42/18639 0.0476190476190476 0.870168067226891 0.677524380103409 0.947593126061296 GO:0051879 Hsp90 protein binding 2/1020 42/18639 0.0476190476190476 0.870168067226891 0.677524380103409 0.947593126061296 GO:0015081 sodium ion transmembrane transporter activity 8/1020 164/18639 0.0487804878048781 0.891391678622669 0.68072231034265 0.950745307233077 GO:0005525 GTP binding 19/1020 378/18639 0.0502645502645503 0.918510737628385 0.682393127204927 0.951758835312135 GO:1901981 phosphatidylinositol phosphate binding 9/1020 185/18639 0.0486486486486487 0.888982511923688 0.688701223580553 0.955056186426889 GO:0015293 symporter activity 7/1020 146/18639 0.0479452054794521 0.876128122481869 0.693189688914022 0.955056186426889 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/1020 21/18639 0.0476190476190476 0.870168067226891 0.693487557853786 0.955056186426889 GO:0005123 death receptor binding 1/1020 21/18639 0.0476190476190476 0.870168067226891 0.693487557853786 0.955056186426889 GO:0005248 voltage-gated sodium channel activity 1/1020 21/18639 0.0476190476190476 0.870168067226891 0.693487557853786 0.955056186426889 GO:0015174 basic amino acid transmembrane transporter activity 1/1020 21/18639 0.0476190476190476 0.870168067226891 0.693487557853786 0.955056186426889 GO:0051428 peptide hormone receptor binding 1/1020 21/18639 0.0476190476190476 0.870168067226891 0.693487557853786 0.955056186426889 GO:0061891 calcium ion sensor activity 1/1020 21/18639 0.0476190476190476 0.870168067226891 0.693487557853786 0.955056186426889 GO:0019001 guanyl nucleotide binding 20/1020 400/18639 0.05 0.913676470588235 0.694241438395713 0.955056186426889 GO:0032561 guanyl ribonucleotide binding 20/1020 400/18639 0.05 0.913676470588235 0.694241438395713 0.955056186426889 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 4/1020 86/18639 0.0465116279069767 0.849931600547196 0.699452916252279 0.959170563979347 GO:0042578 phosphoric ester hydrolase activity 18/1020 363/18639 0.0495867768595041 0.906125425376762 0.701063397264429 0.959170563979347 GO:0019205 nucleobase-containing compound kinase activity 2/1020 44/18639 0.0454545454545455 0.830614973262032 0.702178194555312 0.959170563979347 GO:0030547 signaling receptor inhibitor activity 2/1020 44/18639 0.0454545454545455 0.830614973262032 0.702178194555312 0.959170563979347 GO:0043014 alpha-tubulin binding 2/1020 44/18639 0.0454545454545455 0.830614973262032 0.702178194555312 0.959170563979347 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 6/1020 128/18639 0.046875 0.856571691176471 0.707965497450036 0.959170563979347 GO:0005243 gap junction channel activity 1/1020 22/18639 0.0454545454545455 0.830614973262032 0.710280053878555 0.959170563979347 GO:0008093 cytoskeletal anchor activity 1/1020 22/18639 0.0454545454545455 0.830614973262032 0.710280053878555 0.959170563979347 GO:0034062 5'-3' RNA polymerase activity 1/1020 22/18639 0.0454545454545455 0.830614973262032 0.710280053878555 0.959170563979347 GO:0097747 RNA polymerase activity 1/1020 22/18639 0.0454545454545455 0.830614973262032 0.710280053878555 0.959170563979347 GO:0140784 metal ion sensor activity 1/1020 22/18639 0.0454545454545455 0.830614973262032 0.710280053878555 0.959170563979347 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 3/1020 67/18639 0.0447761194029851 0.818217734855136 0.717406532084622 0.959170563979347 GO:0042054 histone methyltransferase activity 3/1020 67/18639 0.0447761194029851 0.818217734855136 0.717406532084622 0.959170563979347 GO:0016298 lipase activity 6/1020 130/18639 0.0461538461538462 0.843393665158371 0.721889009829553 0.959170563979347 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 4/1020 89/18639 0.0449438202247191 0.82128222075347 0.724732111066579 0.959170563979347 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 4/1020 89/18639 0.0449438202247191 0.82128222075347 0.724732111066579 0.959170563979347 GO:0030276 clathrin binding 2/1020 46/18639 0.0434782608695652 0.794501278772378 0.725243479877029 0.959170563979347 GO:0003887 DNA-directed DNA polymerase activity 1/1020 23/18639 0.0434782608695652 0.794501278772378 0.726153413981894 0.959170563979347 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 1/1020 23/18639 0.0434782608695652 0.794501278772378 0.726153413981894 0.959170563979347 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/1020 23/18639 0.0434782608695652 0.794501278772378 0.726153413981894 0.959170563979347 GO:0005212 structural constituent of eye lens 1/1020 23/18639 0.0434782608695652 0.794501278772378 0.726153413981894 0.959170563979347 GO:0005283 amino acid:sodium symporter activity 1/1020 23/18639 0.0434782608695652 0.794501278772378 0.726153413981894 0.959170563979347 GO:0008171 O-methyltransferase activity 1/1020 23/18639 0.0434782608695652 0.794501278772378 0.726153413981894 0.959170563979347 GO:0016493 C-C chemokine receptor activity 1/1020 23/18639 0.0434782608695652 0.794501278772378 0.726153413981894 0.959170563979347 GO:0016917 GABA receptor activity 1/1020 23/18639 0.0434782608695652 0.794501278772378 0.726153413981894 0.959170563979347 GO:0042171 lysophosphatidic acid acyltransferase activity 1/1020 23/18639 0.0434782608695652 0.794501278772378 0.726153413981894 0.959170563979347 GO:0043274 phospholipase binding 1/1020 23/18639 0.0434782608695652 0.794501278772378 0.726153413981894 0.959170563979347 GO:0071617 lysophospholipid acyltransferase activity 1/1020 23/18639 0.0434782608695652 0.794501278772378 0.726153413981894 0.959170563979347 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 1/1020 23/18639 0.0434782608695652 0.794501278772378 0.726153413981894 0.959170563979347 GO:0005096 GTPase activator activity 13/1020 271/18639 0.0479704797047971 0.876589971782071 0.726695819889938 0.959170563979347 GO:0003777 microtubule motor activity 3/1020 68/18639 0.0441176470588235 0.806185121107266 0.726759821565285 0.959170563979347 GO:0140793 histone H2AXY142 phosphatase activity 4/1020 90/18639 0.0444444444444444 0.812156862745098 0.732798246354181 0.961786089724142 GO:1902936 phosphatidylinositol bisphosphate binding 5/1020 111/18639 0.045045045045045 0.823131955484897 0.733189797015144 0.961786089724142 GO:0002039 p53 binding 3/1020 69/18639 0.0434782608695652 0.794501278772378 0.735868810132472 0.961786089724142 GO:0016279 protein-lysine N-methyltransferase activity 3/1020 69/18639 0.0434782608695652 0.794501278772378 0.735868810132472 0.961786089724142 GO:0001784 phosphotyrosine residue binding 2/1020 47/18639 0.0425531914893617 0.777596996245307 0.736198455415368 0.961786089724142 GO:0140359 ABC-type transporter activity 2/1020 47/18639 0.0425531914893617 0.777596996245307 0.736198455415368 0.961786089724142 GO:0140938 histone H3 methyltransferase activity 2/1020 47/18639 0.0425531914893617 0.777596996245307 0.736198455415368 0.961786089724142 GO:0030695 GTPase regulator activity 24/1020 489/18639 0.049079754601227 0.896860339227716 0.739093271853172 0.961786089724142 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/1020 24/18639 0.0416666666666667 0.761397058823529 0.741157900323668 0.961786089724142 GO:0005315 phosphate transmembrane transporter activity 1/1020 24/18639 0.0416666666666667 0.761397058823529 0.741157900323668 0.961786089724142 GO:0015295 solute:proton symporter activity 1/1020 24/18639 0.0416666666666667 0.761397058823529 0.741157900323668 0.961786089724142 GO:0019957 C-C chemokine binding 1/1020 24/18639 0.0416666666666667 0.761397058823529 0.741157900323668 0.961786089724142 GO:0050699 WW domain binding 1/1020 24/18639 0.0416666666666667 0.761397058823529 0.741157900323668 0.961786089724142 GO:0008028 monocarboxylic acid transmembrane transporter activity 3/1020 70/18639 0.0428571428571429 0.783151260504202 0.744735956843239 0.963944869590156 GO:0016278 lysine N-methyltransferase activity 3/1020 70/18639 0.0428571428571429 0.783151260504202 0.744735956843239 0.963944869590156 GO:0140693 molecular condensate scaffold activity 2/1020 48/18639 0.0416666666666667 0.761397058823529 0.746778705903196 0.964041085268147 GO:0015271 outward rectifier potassium channel activity 1/1020 25/18639 0.04 0.730941176470588 0.755341029073056 0.964041085268147 GO:0015645 fatty acid ligase activity 1/1020 25/18639 0.04 0.730941176470588 0.755341029073056 0.964041085268147 GO:0015662 P-type ion transporter activity 1/1020 25/18639 0.04 0.730941176470588 0.755341029073056 0.964041085268147 GO:0017025 TBP-class protein binding 1/1020 25/18639 0.04 0.730941176470588 0.755341029073056 0.964041085268147 GO:0017056 structural constituent of nuclear pore 1/1020 25/18639 0.04 0.730941176470588 0.755341029073056 0.964041085268147 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/1020 25/18639 0.04 0.730941176470588 0.755341029073056 0.964041085268147 GO:0019707 protein-cysteine S-acyltransferase activity 1/1020 25/18639 0.04 0.730941176470588 0.755341029073056 0.964041085268147 GO:0047617 fatty acyl-CoA hydrolase activity 1/1020 25/18639 0.04 0.730941176470588 0.755341029073056 0.964041085268147 GO:0120515 fatty acid-CoA ligase activity 1/1020 25/18639 0.04 0.730941176470588 0.755341029073056 0.964041085268147 GO:0140358 P-type transmembrane transporter activity 1/1020 25/18639 0.04 0.730941176470588 0.755341029073056 0.964041085268147 GO:0035254 glutamate receptor binding 2/1020 49/18639 0.0408163265306122 0.745858343337335 0.756992391554667 0.964925744677911 GO:0016779 nucleotidyltransferase activity 6/1020 136/18639 0.0441176470588235 0.806185121107266 0.760848771752811 0.966203757026845 GO:0017124 SH3 domain binding 5/1020 115/18639 0.0434782608695652 0.794501278772378 0.760911895057718 0.966203757026845 GO:0032813 tumor necrosis factor receptor superfamily binding 2/1020 50/18639 0.04 0.730941176470588 0.766847902278527 0.966203757026845 GO:0015294 solute:monoatomic cation symporter activity 5/1020 116/18639 0.0431034482758621 0.787652129817444 0.767492374955117 0.966203757026845 GO:0004435 phosphatidylinositol phospholipase C activity 1/1020 26/18639 0.0384615384615385 0.702828054298643 0.768747720291789 0.966203757026845 GO:0005112 Notch binding 1/1020 26/18639 0.0384615384615385 0.702828054298643 0.768747720291789 0.966203757026845 GO:0008157 protein phosphatase 1 binding 1/1020 26/18639 0.0384615384615385 0.702828054298643 0.768747720291789 0.966203757026845 GO:0016289 acyl-CoA hydrolase activity 1/1020 26/18639 0.0384615384615385 0.702828054298643 0.768747720291789 0.966203757026845 GO:0030507 spectrin binding 1/1020 26/18639 0.0384615384615385 0.702828054298643 0.768747720291789 0.966203757026845 GO:0051139 metal cation:proton antiporter activity 1/1020 26/18639 0.0384615384615385 0.702828054298643 0.768747720291789 0.966203757026845 GO:0052742 phosphatidylinositol kinase activity 1/1020 26/18639 0.0384615384615385 0.702828054298643 0.768747720291789 0.966203757026845 GO:0004521 RNA endonuclease activity 3/1020 73/18639 0.0410958904109589 0.750966962127317 0.769914627182119 0.966203757026845 GO:0008276 protein methyltransferase activity 4/1020 95/18639 0.0421052631578947 0.769411764705882 0.770468338522897 0.966203757026845 GO:0003684 damaged DNA binding 3/1020 74/18639 0.0405405405405405 0.740818759936407 0.777843756323547 0.972670435996897 GO:0001671 ATPase activator activity 1/1020 27/18639 0.037037037037037 0.676797385620915 0.781420439643982 0.972670435996897 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/1020 27/18639 0.037037037037037 0.676797385620915 0.781420439643982 0.972670435996897 GO:0005104 fibroblast growth factor receptor binding 1/1020 27/18639 0.037037037037037 0.676797385620915 0.781420439643982 0.972670435996897 GO:0035255 ionotropic glutamate receptor binding 1/1020 27/18639 0.037037037037037 0.676797385620915 0.781420439643982 0.972670435996897 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/1020 27/18639 0.037037037037037 0.676797385620915 0.781420439643982 0.972670435996897 GO:0035091 phosphatidylinositol binding 13/1020 284/18639 0.0457746478873239 0.836464374482187 0.784162116810175 0.974194013259204 GO:0030159 signaling receptor complex adaptor activity 2/1020 52/18639 0.0384615384615385 0.702828054298643 0.785518814725457 0.974194013259204 GO:0019003 GDP binding 3/1020 75/18639 0.04 0.730941176470588 0.785546711783986 0.974194013259204 GO:0015631 tubulin binding 18/1020 385/18639 0.0467532467532468 0.854346829640947 0.787323930973998 0.974333082566483 GO:0004725 protein tyrosine phosphatase activity 4/1020 98/18639 0.0408163265306122 0.745858343337335 0.79099315853447 0.974333082566483 GO:0051536 iron-sulfur cluster binding 3/1020 76/18639 0.0394736842105263 0.721323529411765 0.79302715113768 0.974333082566483 GO:0005242 inward rectifier potassium channel activity 1/1020 28/18639 0.0357142857142857 0.652626050420168 0.793399332377871 0.974333082566483 GO:0016866 intramolecular transferase activity 1/1020 28/18639 0.0357142857142857 0.652626050420168 0.793399332377871 0.974333082566483 GO:0019789 SUMO transferase activity 1/1020 28/18639 0.0357142857142857 0.652626050420168 0.793399332377871 0.974333082566483 GO:0046966 nuclear thyroid hormone receptor binding 1/1020 28/18639 0.0357142857142857 0.652626050420168 0.793399332377871 0.974333082566483 GO:0051393 alpha-actinin binding 1/1020 28/18639 0.0357142857142857 0.652626050420168 0.793399332377871 0.974333082566483 GO:0015108 chloride transmembrane transporter activity 5/1020 121/18639 0.0413223140495868 0.755104521147302 0.798338799676327 0.977542268096504 GO:0003724 RNA helicase activity 3/1020 77/18639 0.038961038961039 0.711955691367456 0.800288861774207 0.977542268096504 GO:0051287 NAD binding 2/1020 54/18639 0.037037037037037 0.676797385620915 0.802861390223119 0.977542268096504 GO:0004181 metallocarboxypeptidase activity 1/1020 29/18639 0.0344827586206897 0.630121703853955 0.80472235000049 0.977542268096504 GO:0004629 phospholipase C activity 1/1020 29/18639 0.0344827586206897 0.630121703853955 0.80472235000049 0.977542268096504 GO:0005416 amino acid:monoatomic cation symporter activity 1/1020 29/18639 0.0344827586206897 0.630121703853955 0.80472235000049 0.977542268096504 GO:0016417 S-acyltransferase activity 1/1020 29/18639 0.0344827586206897 0.630121703853955 0.80472235000049 0.977542268096504 GO:0106222 lncRNA binding 1/1020 29/18639 0.0344827586206897 0.630121703853955 0.80472235000049 0.977542268096504 GO:0015103 inorganic anion transmembrane transporter activity 7/1020 165/18639 0.0424242424242424 0.77524064171123 0.804749295185702 0.977542268096504 GO:0046943 carboxylic acid transmembrane transporter activity 8/1020 188/18639 0.0425531914893617 0.777596996245307 0.813566850994145 0.980021621024743 GO:0008186 ATP-dependent activity, acting on RNA 3/1020 79/18639 0.0379746835443038 0.693931496649293 0.814171794389726 0.980021621024743 GO:0015370 solute:sodium symporter activity 3/1020 79/18639 0.0379746835443038 0.693931496649293 0.814171794389726 0.980021621024743 GO:0048019 receptor antagonist activity 1/1020 30/18639 0.0333333333333333 0.609117647058823 0.815425370043451 0.980021621024743 GO:0051721 protein phosphatase 2A binding 1/1020 30/18639 0.0333333333333333 0.609117647058823 0.815425370043451 0.980021621024743 GO:0005342 organic acid transmembrane transporter activity 8/1020 189/18639 0.0423280423280423 0.773482726423903 0.818029783800568 0.980021621024743 GO:0016791 phosphatase activity 12/1020 273/18639 0.043956043956044 0.803232062055592 0.820593946310322 0.980021621024743 GO:0051020 GTPase binding 14/1020 315/18639 0.0444444444444444 0.812156862745098 0.82397955523726 0.980021621024743 GO:0005164 tumor necrosis factor receptor binding 1/1020 31/18639 0.032258064516129 0.589468690702087 0.825542309296268 0.980021621024743 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/1020 31/18639 0.032258064516129 0.589468690702087 0.825542309296268 0.980021621024743 GO:0008327 methyl-CpG binding 1/1020 31/18639 0.032258064516129 0.589468690702087 0.825542309296268 0.980021621024743 GO:0016411 acylglycerol O-acyltransferase activity 1/1020 31/18639 0.032258064516129 0.589468690702087 0.825542309296268 0.980021621024743 GO:0016887 ATP hydrolysis activity 19/1020 417/18639 0.0455635491606715 0.832606855691917 0.825914069277437 0.980021621024743 GO:0033192 calmodulin-dependent protein phosphatase activity 3/1020 81/18639 0.037037037037037 0.676797385620915 0.82722778338732 0.980021621024743 GO:0140791 histone H2AXS140 phosphatase activity 3/1020 81/18639 0.037037037037037 0.676797385620915 0.82722778338732 0.980021621024743 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 3/1020 81/18639 0.037037037037037 0.676797385620915 0.82722778338732 0.980021621024743 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 3/1020 81/18639 0.037037037037037 0.676797385620915 0.82722778338732 0.980021621024743 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 3/1020 81/18639 0.037037037037037 0.676797385620915 0.82722778338732 0.980021621024743 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 3/1020 81/18639 0.037037037037037 0.676797385620915 0.82722778338732 0.980021621024743 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 3/1020 81/18639 0.037037037037037 0.676797385620915 0.82722778338732 0.980021621024743 GO:1990439 MAP kinase serine/threonine phosphatase activity 3/1020 81/18639 0.037037037037037 0.676797385620915 0.82722778338732 0.980021621024743 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 3/1020 82/18639 0.0365853658536585 0.668543758967001 0.833456069375629 0.983228249670098 GO:0033549 MAP kinase phosphatase activity 3/1020 82/18639 0.0365853658536585 0.668543758967001 0.833456069375629 0.983228249670098 GO:0015106 bicarbonate transmembrane transporter activity 1/1020 32/18639 0.03125 0.571047794117647 0.835105230863219 0.983228249670098 GO:0042910 xenobiotic transmembrane transporter activity 1/1020 32/18639 0.03125 0.571047794117647 0.835105230863219 0.983228249670098 GO:0140142 nucleocytoplasmic carrier activity 1/1020 32/18639 0.03125 0.571047794117647 0.835105230863219 0.983228249670098 GO:0019842 vitamin binding 6/1020 150/18639 0.04 0.730941176470588 0.835792831894344 0.983228249670098 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 3/1020 83/18639 0.036144578313253 0.660489014883062 0.839490193406497 0.986425466464811 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/1020 33/18639 0.0303030303030303 0.553743315508021 0.84414444538031 0.987883441780386 GO:0004527 exonuclease activity 3/1020 84/18639 0.0357142857142857 0.652626050420168 0.845334429748357 0.987883441780386 GO:0017018 myosin phosphatase activity 3/1020 84/18639 0.0357142857142857 0.652626050420168 0.845334429748357 0.987883441780386 GO:0003823 antigen binding 7/1020 174/18639 0.0402298850574713 0.735141987829615 0.845408765348312 0.987883441780386 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 5/1020 130/18639 0.0384615384615385 0.702828054298643 0.84563607429463 0.987883441780386 GO:0001098 basal transcription machinery binding 2/1020 60/18639 0.0333333333333333 0.609117647058823 0.847627276261088 0.987917438883004 GO:0001099 basal RNA polymerase II transcription machinery binding 2/1020 60/18639 0.0333333333333333 0.609117647058823 0.847627276261088 0.987917438883004 GO:0003774 cytoskeletal motor activity 6/1020 153/18639 0.0392156862745098 0.716608996539792 0.849113757301131 0.988098304899439 GO:0008376 acetylgalactosaminyltransferase activity 1/1020 34/18639 0.0294117647058824 0.537456747404844 0.852688606710638 0.988098304899439 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/1020 34/18639 0.0294117647058824 0.537456747404844 0.852688606710638 0.988098304899439 GO:0030332 cyclin binding 1/1020 34/18639 0.0294117647058824 0.537456747404844 0.852688606710638 0.988098304899439 GO:0090482 vitamin transmembrane transporter activity 1/1020 34/18639 0.0294117647058824 0.537456747404844 0.852688606710638 0.988098304899439 GO:0016836 hydro-lyase activity 2/1020 61/18639 0.0327868852459016 0.599132111861138 0.854121164271895 0.988620703933101 GO:0046873 metal ion transmembrane transporter activity 20/1020 450/18639 0.0444444444444444 0.812156862745098 0.860374898501754 0.992886776673529 GO:0005154 epidermal growth factor receptor binding 1/1020 35/18639 0.0285714285714286 0.522100840336134 0.860764802419058 0.992886776673529 GO:0034061 DNA polymerase activity 1/1020 35/18639 0.0285714285714286 0.522100840336134 0.860764802419058 0.992886776673529 GO:1901682 sulfur compound transmembrane transporter activity 2/1020 63/18639 0.0317460317460317 0.580112044817927 0.866356594067674 0.997123637156099 GO:0000993 RNA polymerase II complex binding 1/1020 36/18639 0.0277777777777778 0.507598039215686 0.868398639310724 0.997123637156099 GO:0004190 aspartic-type endopeptidase activity 1/1020 36/18639 0.0277777777777778 0.507598039215686 0.868398639310724 0.997123637156099 GO:0016409 palmitoyltransferase activity 1/1020 36/18639 0.0277777777777778 0.507598039215686 0.868398639310724 0.997123637156099 GO:0016757 glycosyltransferase activity 11/1020 267/18639 0.0411985018726592 0.752842035690681 0.870272787702395 0.998137468355708 GO:0070001 aspartic-type peptidase activity 1/1020 37/18639 0.027027027027027 0.493879173290938 0.875614324302556 0.999999998775837 GO:0016922 nuclear receptor binding 5/1020 137/18639 0.0364963503649635 0.66691713181623 0.875747049400367 0.999999998775837 GO:0042887 amide transmembrane transporter activity 1/1020 38/18639 0.0263157894736842 0.480882352941176 0.882434740882031 0.999999998775837 GO:0140767 enzyme-substrate adaptor activity 5/1020 139/18639 0.0359712230215827 0.65732120186204 0.88337664006212 0.999999998775837 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 9/1020 229/18639 0.0393013100436681 0.718173645003853 0.885175250684619 0.999999998775837 GO:0005085 guanyl-nucleotide exchange factor activity 9/1020 230/18639 0.0391304347826087 0.715051150895141 0.888063074341007 0.999999998775837 GO:0004518 nuclease activity 8/1020 209/18639 0.0382775119617225 0.699465240641711 0.890957253151511 0.999999998775837 GO:0005548 phospholipid transporter activity 2/1020 68/18639 0.0294117647058824 0.537456747404844 0.8929317534722 0.999999998775837 GO:0030145 manganese ion binding 2/1020 68/18639 0.0294117647058824 0.537456747404844 0.8929317534722 0.999999998775837 GO:1990841 promoter-specific chromatin binding 2/1020 68/18639 0.0294117647058824 0.537456747404844 0.8929317534722 0.999999998775837 GO:0016410 N-acyltransferase activity 3/1020 94/18639 0.0319148936170213 0.58319774718398 0.894276336144829 0.999999998775837 GO:0030331 nuclear estrogen receptor binding 1/1020 40/18639 0.025 0.456838235294118 0.894975115381929 0.999999998775837 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 6/1020 167/18639 0.0359281437125748 0.656533990841846 0.900060542399769 0.999999998775837 GO:0001727 lipid kinase activity 1/1020 41/18639 0.024390243902439 0.445695839311334 0.900734854201781 0.999999998775837 GO:0042169 SH2 domain binding 1/1020 41/18639 0.024390243902439 0.445695839311334 0.900734854201781 0.999999998775837 GO:0004540 RNA nuclease activity 4/1020 121/18639 0.0330578512396694 0.604083616917842 0.903434570535539 0.999999998775837 GO:0004520 DNA endonuclease activity 1/1020 42/18639 0.0238095238095238 0.435084033613445 0.906179012106619 0.999999998775837 GO:0005249 voltage-gated potassium channel activity 3/1020 98/18639 0.0306122448979592 0.559393757503001 0.909604861188096 0.999999998775837 GO:0015085 calcium ion transmembrane transporter activity 5/1020 147/18639 0.0340136054421769 0.621548619447779 0.910007301050354 0.999999998775837 GO:0008375 acetylglucosaminyltransferase activity 1/1020 43/18639 0.0232558139534884 0.424965800273598 0.911324863999465 0.999999998775837 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/1020 43/18639 0.0232558139534884 0.424965800273598 0.911324863999465 0.999999998775837 GO:0005267 potassium channel activity 4/1020 124/18639 0.032258064516129 0.589468690702087 0.913224914474068 0.999999998775837 GO:0008509 monoatomic anion transmembrane transporter activity 5/1020 149/18639 0.0335570469798658 0.613205684958547 0.915770413987583 0.999999998775837 GO:0051539 4 iron, 4 sulfur cluster binding 1/1020 45/18639 0.0222222222222222 0.406078431372549 0.920786077229409 0.999999998775837 GO:0140303 intramembrane lipid transporter activity 1/1020 45/18639 0.0222222222222222 0.406078431372549 0.920786077229409 0.999999998775837 GO:0000510 H3-H4 histone complex chaperone activity 5/1020 151/18639 0.033112582781457 0.605083755356447 0.921206119897638 0.999999998775837 GO:0140584 chromatin extrusion motor activity 5/1020 151/18639 0.033112582781457 0.605083755356447 0.921206119897638 0.999999998775837 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 5/1020 151/18639 0.033112582781457 0.605083755356447 0.921206119897638 0.999999998775837 GO:0140849 ATP-dependent H2AZ histone chaperone activity 5/1020 151/18639 0.033112582781457 0.605083755356447 0.921206119897638 0.999999998775837 GO:0004519 endonuclease activity 4/1020 127/18639 0.031496062992126 0.575544233441408 0.922120691907584 0.999999998775837 GO:0015616 DNA translocase activity 5/1020 152/18639 0.0328947368421053 0.601102941176471 0.92380582892086 0.999999998775837 GO:0140674 ATP-dependent histone chaperone activity 5/1020 152/18639 0.0328947368421053 0.601102941176471 0.92380582892086 0.999999998775837 GO:0001653 peptide receptor activity 4/1020 128/18639 0.03125 0.571047794117647 0.924898872841969 0.999999998775837 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/1020 46/18639 0.0217391304347826 0.397250639386189 0.925131468281684 0.999999998775837 GO:0004722 protein serine/threonine phosphatase activity 3/1020 103/18639 0.029126213592233 0.532238720731011 0.925919017196075 0.999999998775837 GO:0061775 cohesin loader activity 5/1020 153/18639 0.0326797385620915 0.59717416378316 0.926329209718824 0.999999998775837 GO:0035591 signaling adaptor activity 4/1020 129/18639 0.0310077519379845 0.566621067031464 0.927587586474826 0.999999998775837 GO:0061733 protein-lysine-acetyltransferase activity 1/1020 47/18639 0.0212765957446809 0.388798498122653 0.929238707691821 0.999999998775837 GO:0099095 ligand-gated monoatomic anion channel activity 1/1020 47/18639 0.0212765957446809 0.388798498122653 0.929238707691821 0.999999998775837 GO:0005262 calcium channel activity 4/1020 131/18639 0.0305343511450382 0.557970363718006 0.932706130064674 0.999999998775837 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/1020 48/18639 0.0208333333333333 0.380698529411765 0.933120835389451 0.999999998775837 GO:0008168 methyltransferase activity 7/1020 204/18639 0.0343137254901961 0.627032871972318 0.934318114178361 0.999999998775837 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 6/1020 181/18639 0.0331491712707182 0.605752356191095 0.93549049839904 0.999999998775837 GO:0001222 transcription corepressor binding 1/1020 49/18639 0.0204081632653061 0.372929171668667 0.936790177969343 0.999999998775837 GO:0140658 ATP-dependent chromatin remodeler activity 5/1020 158/18639 0.0316455696202532 0.578276247207744 0.93786345333835 0.999999998775837 GO:0000287 magnesium ion binding 8/1020 230/18639 0.0347826086956522 0.635601023017903 0.939498737704893 0.999999998775837 GO:0003689 DNA clamp loader activity 5/1020 160/18639 0.03125 0.571047794117647 0.942004159429554 0.999999998775837 GO:0015079 potassium ion transmembrane transporter activity 5/1020 160/18639 0.03125 0.571047794117647 0.942004159429554 0.999999998775837 GO:0016597 amino acid binding 1/1020 51/18639 0.0196078431372549 0.358304498269896 0.94353647926746 0.999999998775837 GO:0030544 Hsp70 protein binding 1/1020 51/18639 0.0196078431372549 0.358304498269896 0.94353647926746 0.999999998775837 GO:0099094 ligand-gated monoatomic cation channel activity 4/1020 136/18639 0.0294117647058824 0.537456747404844 0.944099312951799 0.999999998775837 GO:0022834 ligand-gated channel activity 6/1020 188/18639 0.0319148936170213 0.58319774718398 0.948622716226983 0.999999998775837 GO:0140597 protein carrier chaperone 6/1020 188/18639 0.0319148936170213 0.58319774718398 0.948622716226983 0.999999998775837 GO:0140713 histone chaperone activity 5/1020 164/18639 0.0304878048780488 0.557119799139168 0.949547501850002 0.999999998775837 GO:0034212 protein N-acetyltransferase activity 1/1020 53/18639 0.0188679245283019 0.344783573806881 0.949563386816712 0.999999998775837 GO:0051018 protein kinase A binding 1/1020 53/18639 0.0188679245283019 0.344783573806881 0.949563386816712 0.999999998775837 GO:0031267 small GTPase binding 10/1020 283/18639 0.0353356890459364 0.645707753065891 0.95042555995054 0.999999998775837 GO:0140463 chromatin-protein adaptor activity 1/1020 54/18639 0.0185185185185185 0.338398692810457 0.952331349016592 0.999999998775837 GO:0016741 transferase activity, transferring one-carbon groups 7/1020 215/18639 0.0325581395348837 0.594952120383037 0.95326009394547 0.999999998775837 GO:0030170 pyridoxal phosphate binding 1/1020 56/18639 0.0178571428571429 0.326313025210084 0.957420291694036 0.999999998775837 GO:0070279 vitamin B6 binding 1/1020 57/18639 0.0175438596491228 0.320588235294118 0.95975744406298 0.999999998775837 GO:0008194 UDP-glycosyltransferase activity 4/1020 145/18639 0.0275862068965517 0.504097363083164 0.960267415368645 0.999999998775837 GO:0016758 hexosyltransferase activity 6/1020 197/18639 0.0304568527918782 0.556554195282174 0.961958724661701 0.999999998775837 GO:0008408 3'-5' exonuclease activity 1/1020 58/18639 0.0172413793103448 0.315060851926978 0.961966431634596 0.999999998775837 GO:0036002 pre-mRNA binding 1/1020 59/18639 0.0169491525423729 0.309720837487537 0.964054276192623 0.999999998775837 GO:0022832 voltage-gated channel activity 5/1020 175/18639 0.0285714285714286 0.522100840336134 0.96592232893885 0.999999998775837 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/1020 60/18639 0.0166666666666667 0.304558823529412 0.966027615174514 0.999999998775837 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/1020 60/18639 0.0166666666666667 0.304558823529412 0.966027615174514 0.999999998775837 GO:0008528 G protein-coupled peptide receptor activity 3/1020 122/18639 0.0245901639344262 0.449349083895853 0.96620511812469 0.999999998775837 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 3/1020 122/18639 0.0245901639344262 0.449349083895853 0.96620511812469 0.999999998775837 GO:0046982 protein heterodimerization activity 13/1020 369/18639 0.035230352303523 0.643782879005261 0.969129014648393 0.999999998775837 GO:0016407 acetyltransferase activity 2/1020 96/18639 0.0208333333333333 0.380698529411765 0.970745306324319 0.999999998775837 GO:0022824 transmitter-gated monoatomic ion channel activity 1/1020 63/18639 0.0158730158730159 0.290056022408964 0.971321641248716 0.999999998775837 GO:0022835 transmitter-gated channel activity 1/1020 63/18639 0.0158730158730159 0.290056022408964 0.971321641248716 0.999999998775837 GO:0030594 neurotransmitter receptor activity 2/1020 97/18639 0.0206185567010309 0.376773802304427 0.972108915074332 0.999999998775837 GO:0004536 DNA nuclease activity 1/1020 64/18639 0.015625 0.285523897058824 0.97289635733002 0.999999998775837 GO:0160215 deacylase activity 1/1020 65/18639 0.0153846153846154 0.281131221719457 0.974384686564118 0.999999998775837 GO:0043130 ubiquitin binding 2/1020 100/18639 0.02 0.365470588235294 0.975841521128275 0.999999998775837 GO:0045182 translation regulator activity 12/1020 356/18639 0.0337078651685393 0.615961665565102 0.976493912107301 0.999999998775837 GO:0015276 ligand-gated monoatomic ion channel activity 5/1020 186/18639 0.0268817204301075 0.491223908918406 0.977267795342775 0.999999998775837 GO:0008080 N-acetyltransferase activity 1/1020 69/18639 0.0144927536231884 0.264833759590793 0.979565023963817 0.999999998775837 GO:0022836 gated channel activity 10/1020 318/18639 0.0314465408805031 0.574639289678135 0.982084054212611 0.999999998775837 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/1020 73/18639 0.0136986301369863 0.250322320709106 0.983698527167931 0.999999998775837 GO:0042393 histone binding 7/1020 247/18639 0.0283400809716599 0.517873303167421 0.983761631862941 0.999999998775837 GO:0022843 voltage-gated monoatomic cation channel activity 3/1020 143/18639 0.020979020979021 0.383360756890169 0.986400834323044 0.999999998775837 GO:0005244 voltage-gated monoatomic ion channel activity 4/1020 173/18639 0.023121387283237 0.422509350561034 0.986975432769519 0.999999998775837 GO:0032182 ubiquitin-like protein binding 2/1020 120/18639 0.0166666666666667 0.304558823529412 0.990876875523287 0.999999998775837 GO:0008094 ATP-dependent activity, acting on DNA 5/1020 210/18639 0.0238095238095238 0.435084033613445 0.990951703594261 0.999999998775837 GO:0004386 helicase activity 3/1020 155/18639 0.0193548387096774 0.353681214421252 0.992046338056535 0.999999998775837 GO:0050660 flavin adenine dinucleotide binding 1/1020 86/18639 0.0116279069767442 0.212482900136799 0.99218196061942 0.999999998775837 GO:0140101 catalytic activity, acting on a tRNA 2/1020 139/18639 0.0143884892086331 0.262928480744816 0.996458465469437 0.999999998775837 GO:0004497 monooxygenase activity 1/1020 106/18639 0.00943396226415094 0.172391786903441 0.997478373910827 0.999999998775837 GO:0141003 histone H2AX kinase activity 9/1020 354/18639 0.0254237288135593 0.464581256231306 0.997649014374129 0.999999998775837 GO:0140996 histone H3 kinase activity 9/1020 357/18639 0.0252100840336134 0.460677212061295 0.997888043085005 0.999999998775837 GO:0035173 histone kinase activity 9/1020 360/18639 0.025 0.456838235294118 0.998103749020062 0.999999998775837 GO:0140097 catalytic activity, acting on DNA 8/1020 336/18639 0.0238095238095238 0.435084033613445 0.998296650372889 0.999999998775837 GO:0061630 ubiquitin protein ligase activity 8/1020 353/18639 0.0226628895184136 0.414130978170305 0.999104345984888 0.999999998775837 GO:0019783 ubiquitin-like protein peptidase activity 1/1020 127/18639 0.0078740157480315 0.143886058360352 0.999232452753655 0.999999998775837 GO:0140098 catalytic activity, acting on RNA 9/1020 387/18639 0.0232558139534884 0.424965800273598 0.999296620936047 0.999999998775837 GO:0061659 ubiquitin-like protein ligase activity 8/1020 372/18639 0.021505376344086 0.392979127134725 0.999571053575868 0.999999998775837 GO:0016755 aminoacyltransferase activity 12/1020 496/18639 0.0241935483870968 0.442101518026565 0.99974520107241 0.999999998775837 GO:0019787 ubiquitin-like protein transferase activity 9/1020 479/18639 0.0187891440501044 0.343343976421466 0.999981383649051 0.999999998775837 GO:0004842 ubiquitin-protein transferase activity 8/1020 449/18639 0.0178173719376392 0.325586270142801 0.999981557633355 0.999999998775837 GO:0004674 protein serine/threonine kinase activity 6/1020 433/18639 0.0138568129330254 0.253212878684961 0.999997837125803 0.999999998775837 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 1/1020 243/18639 0.00411522633744856 0.075199709513435 0.999998951105204 0.999999998775837 GO:0004676 3-phosphoinositide-dependent protein kinase activity 1/1020 245/18639 0.00408163265306122 0.0745858343337335 0.999999064199315 0.999999998775837 GO:0004711 ribosomal protein S6 kinase activity 1/1020 245/18639 0.00408163265306122 0.0745858343337335 0.999999064199315 0.999999998775837 GO:0035175 histone H3S10 kinase activity 1/1020 245/18639 0.00408163265306122 0.0745858343337335 0.999999064199315 0.999999998775837 GO:0035979 histone H2AXS139 kinase activity 1/1020 245/18639 0.00408163265306122 0.0745858343337335 0.999999064199315 0.999999998775837 GO:0044022 histone H3S28 kinase activity 1/1020 245/18639 0.00408163265306122 0.0745858343337335 0.999999064199315 0.999999998775837 GO:0044023 histone H4S1 kinase activity 1/1020 245/18639 0.00408163265306122 0.0745858343337335 0.999999064199315 0.999999998775837 GO:0044024 histone H2AS1 kinase activity 1/1020 245/18639 0.00408163265306122 0.0745858343337335 0.999999064199315 0.999999998775837 GO:0044025 histone H2BS14 kinase activity 1/1020 245/18639 0.00408163265306122 0.0745858343337335 0.999999064199315 0.999999998775837 GO:0072354 histone H3T3 kinase activity 1/1020 245/18639 0.00408163265306122 0.0745858343337335 0.999999064199315 0.999999998775837 GO:0072371 histone H2AS121 kinase activity 1/1020 245/18639 0.00408163265306122 0.0745858343337335 0.999999064199315 0.999999998775837 GO:0072518 Rho-dependent protein serine/threonine kinase activity 1/1020 245/18639 0.00408163265306122 0.0745858343337335 0.999999064199315 0.999999998775837 GO:0140823 histone H2BS36 kinase activity 1/1020 245/18639 0.00408163265306122 0.0745858343337335 0.999999064199315 0.999999998775837 GO:0140855 histone H3S57 kinase activity 1/1020 245/18639 0.00408163265306122 0.0745858343337335 0.999999064199315 0.999999998775837 GO:0140995 histone H2A kinase activity 1/1020 245/18639 0.00408163265306122 0.0745858343337335 0.999999064199315 0.999999998775837 GO:0140997 histone H4 kinase activity 1/1020 245/18639 0.00408163265306122 0.0745858343337335 0.999999064199315 0.999999998775837 GO:0140998 histone H2B kinase activity 1/1020 245/18639 0.00408163265306122 0.0745858343337335 0.999999064199315 0.999999998775837 GO:1990244 histone H2AT120 kinase activity 1/1020 245/18639 0.00408163265306122 0.0745858343337335 0.999999064199315 0.999999998775837 GO:0004677 DNA-dependent protein kinase activity 1/1020 246/18639 0.0040650406504065 0.0742826398852224 0.999999116092144 0.999999998775837 GO:0140857 histone H3T45 kinase activity 1/1020 246/18639 0.0040650406504065 0.0742826398852224 0.999999116092144 0.999999998775837 GO:0035402 histone H3T11 kinase activity 1/1020 247/18639 0.00404858299595142 0.0739819004524887 0.999999165110032 0.999999998775837 GO:0035403 histone H3T6 kinase activity 1/1020 247/18639 0.00404858299595142 0.0739819004524887 0.999999165110032 0.999999998775837 GO:0004679 AMP-activated protein kinase activity 1/1020 248/18639 0.00403225806451613 0.0736835863377609 0.999999211412107 0.999999998775837 GO:0030371 translation repressor activity 2/1020 329/18639 0.0060790273556231 0.111085285177901 0.999999843354705 0.999999998775837 GO:0106310 protein serine kinase activity 1/1020 361/18639 0.00277008310249307 0.0506191950464396 0.999999998775837 0.999999998775837