ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 75/1051 175/18639 0.428571428571429 7.60051651488378 3.94357783326073e-47 4.19202323675616e-44 GO:0005201 extracellular matrix structural constituent 51/1051 168/18639 0.303571428571429 5.38369919804268 4.55084199614857e-24 2.41877252095296e-21 GO:0019843 rRNA binding 19/1051 65/18639 0.292307692307692 5.18394203322843 1.65155718471735e-09 5.38446053531707e-07 GO:0008201 heparin binding 32/1051 172/18639 0.186046511627907 3.29944902971699 2.0261375485671e-09 5.38446053531707e-07 GO:0005539 glycosaminoglycan binding 38/1051 242/18639 0.15702479338843 2.78476224925494 9.27894830247987e-09 1.97270440910722e-06 GO:0030020 extracellular matrix structural constituent conferring tensile strength 14/1051 44/18639 0.318181818181818 5.64280771559554 7.05173280339315e-08 1.24933199500115e-05 GO:0009055 electron transfer activity 23/1051 116/18639 0.198275862068966 3.51633091636865 1.10361583868787e-07 1.67591948075029e-05 GO:0019838 growth factor binding 25/1051 136/18639 0.183823529411765 3.2600254659428 1.47800107921573e-07 1.79019359726907e-05 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 17/1051 68/18639 0.25 4.43363463368221 1.51568601838397e-07 1.79019359726907e-05 GO:0048027 mRNA 5'-UTR binding 10/1051 24/18639 0.416666666666667 7.38939105613701 2.95533513572643e-07 3.1415212492772e-05 GO:0005518 collagen binding 17/1051 72/18639 0.236111111111111 4.18732159847764 3.69218214051599e-07 3.5679905594259e-05 GO:0048407 platelet-derived growth factor binding 7/1051 11/18639 0.636363636363636 11.2856154311911 4.80112079321819e-07 4.25299283599245e-05 GO:1901681 sulfur compound binding 37/1051 275/18639 0.134545454545455 2.38610154830897 8.08144392140364e-07 6.60813452957852e-05 GO:0045296 cadherin binding 41/1051 334/18639 0.122754491017964 2.17699425126911 2.34486637320707e-06 0.000178042353908508 GO:0050840 extracellular matrix binding 15/1051 67/18639 0.223880597014925 3.97041907493929 3.64583274856319e-06 0.000254064291586412 GO:0005178 integrin binding 25/1051 161/18639 0.15527950310559 2.75381033147963 3.82410975106547e-06 0.000254064291586412 GO:0031720 haptoglobin binding 6/1051 10/18639 0.6 10.6407231208373 5.47004663855187e-06 0.000342038798634155 GO:1990948 ubiquitin ligase inhibitor activity 6/1051 11/18639 0.545454545454545 9.67338465530663 1.14579681096279e-05 0.000676656672251916 GO:0030021 extracellular matrix structural constituent conferring compression resistance 8/1051 22/18639 0.363636363636364 6.44892310353776 1.56419564237603e-05 0.000875126298866166 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 7/1051 17/18639 0.411764705882353 7.30245704371187 2.09604762558988e-05 0.00106099934571526 GO:0019198 transmembrane receptor protein phosphatase activity 7/1051 17/18639 0.411764705882353 7.30245704371187 2.09604762558988e-05 0.00106099934571526 GO:0005344 oxygen carrier activity 6/1051 14/18639 0.428571428571429 7.60051651488378 6.43044723977977e-05 0.00310707518903904 GO:0055105 ubiquitin-protein transferase inhibitor activity 6/1051 15/18639 0.4 7.09381541389153 0.000102065021505749 0.00471717903741787 GO:0003954 NADH dehydrogenase activity 10/1051 44/18639 0.227272727272727 4.0305769397111 0.000133262605140219 0.00590242288600219 GO:0016504 peptidase activator activity 11/1051 57/18639 0.192982456140351 3.42245480494767 0.000293091203362221 0.0124622379669617 GO:0022853 active monoatomic ion transmembrane transporter activity 17/1051 118/18639 0.144067796610169 2.55497589059653 0.000329907893086342 0.0134881573211839 GO:0008137 NADH dehydrogenase (ubiquinone) activity 9/1051 41/18639 0.219512195121951 3.89294748323316 0.000379603722397153 0.0149451391447472 GO:0046332 SMAD binding 13/1051 79/18639 0.164556962025316 2.91834178419588 0.000443820408926004 0.016849324810298 GO:0015078 proton transmembrane transporter activity 22/1051 185/18639 0.118918918918919 2.10897215007586 0.000759637472007324 0.0278446425084064 GO:0098632 cell-cell adhesion mediator activity 10/1051 55/18639 0.181818181818182 3.22446155176888 0.000894868823670548 0.0317081853187264 GO:0038024 cargo receptor activity 11/1051 65/18639 0.169230769230769 3.00122959818488 0.000942041695144158 0.032302913610911 GO:0004129 cytochrome-c oxidase activity 5/1051 15/18639 0.333333333333333 5.91151284490961 0.00105396658857364 0.0342158787903588 GO:0098631 cell adhesion mediator activity 12/1051 76/18639 0.157894736842105 2.80019029495718 0.00106220508003936 0.0342158787903588 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 10/1051 58/18639 0.172413793103448 3.05767905771187 0.00137018598598675 0.0428384618559974 GO:0016675 oxidoreductase activity, acting on a heme group of donors 5/1051 16/18639 0.3125 5.54204329210276 0.00146234789875795 0.0431858829970841 GO:0140297 DNA-binding transcription factor binding 44/1051 488/18639 0.0901639344262295 1.59901576952473 0.00146255107045628 0.0431858829970841 GO:0043178 alcohol binding 13/1051 92/18639 0.141304347826087 2.50596740164647 0.00191180715411508 0.05492570283309 GO:0015026 coreceptor activity 10/1051 61/18639 0.163934426229508 2.90730139913587 0.00203295015259595 0.0568691055844603 GO:0097493 structural molecule activity conferring elasticity 4/1051 11/18639 0.363636363636364 6.44892310353776 0.00240945658067754 0.0647881594990458 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 33/1051 349/18639 0.0945558739255014 1.67690478981677 0.00259769170856684 0.0647881594990458 GO:0070064 proline-rich region binding 5/1051 18/18639 0.277777777777778 4.92626070409134 0.00261057910715151 0.0647881594990458 GO:0098641 cadherin binding involved in cell-cell adhesion 5/1051 18/18639 0.277777777777778 4.92626070409134 0.00261057910715151 0.0647881594990458 GO:0015399 primary active transmembrane transporter activity 19/1051 166/18639 0.114457831325301 2.02985682024005 0.00262078161661239 0.0647881594990458 GO:0034452 dynactin binding 4/1051 12/18639 0.333333333333333 5.91151284490961 0.0034539837232839 0.0830700631928331 GO:0055106 ubiquitin-protein transferase regulator activity 7/1051 36/18639 0.194444444444444 3.44838249286394 0.00351660662622529 0.0830700631928331 GO:0016651 oxidoreductase activity, acting on NAD(P)H 12/1051 88/18639 0.136363636363636 2.41834616382666 0.00379132250118406 0.0876125177991012 GO:0004601 peroxidase activity 9/1051 57/18639 0.157894736842105 2.80019029495718 0.00434983365758596 0.0983802803832739 GO:0070700 BMP receptor binding 4/1051 13/18639 0.307692307692308 5.45678108760887 0.00476840452226886 0.105600291816079 GO:0003785 actin monomer binding 6/1051 29/18639 0.206896551724138 3.66921486925424 0.0049183113741295 0.106697244708156 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 9/1051 59/18639 0.152542372881356 2.70526859004338 0.00549636179135109 0.116852651684124 GO:0008093 cytoskeletal anchor activity 5/1051 22/18639 0.227272727272727 4.0305769397111 0.00665191389250319 0.137289120808292 GO:0033218 amide binding 24/1051 247/18639 0.097165991902834 1.72319402766596 0.0067159306510171 0.137289120808292 GO:0017147 Wnt-protein binding 6/1051 31/18639 0.193548387096774 3.43249132930235 0.0069265284318404 0.138922636283893 GO:0019955 cytokine binding 16/1051 144/18639 0.111111111111111 1.97050428163654 0.00727403888749746 0.143190802544626 GO:0005080 protein kinase C binding 8/1051 52/18639 0.153846153846154 2.72839054380444 0.00821388039899237 0.152453247720464 GO:0005523 tropomyosin binding 4/1051 15/18639 0.266666666666667 4.72921027592769 0.00831823929236776 0.152453247720464 GO:0031386 protein tag activity 4/1051 15/18639 0.266666666666667 4.72921027592769 0.00831823929236776 0.152453247720464 GO:0141047 molecular tag activity 4/1051 15/18639 0.266666666666667 4.72921027592769 0.00831823929236776 0.152453247720464 GO:0004725 protein tyrosine phosphatase activity 12/1051 98/18639 0.122448979591837 2.17157614710965 0.00898888602572799 0.159335239925561 GO:0061134 peptidase regulator activity 22/1051 226/18639 0.0973451327433628 1.72637100780546 0.00899352247933553 0.159335239925561 GO:0140296 general transcription initiation factor binding 8/1051 53/18639 0.150943396226415 2.6769114769402 0.00920846996170387 0.160468910971987 GO:0001091 RNA polymerase II general transcription initiation factor binding 5/1051 24/18639 0.208333333333333 3.69469552806851 0.00978020244914118 0.165021511165668 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 5/1051 24/18639 0.208333333333333 3.69469552806851 0.00978020244914118 0.165021511165668 GO:0004721 phosphoprotein phosphatase activity 18/1051 175/18639 0.102857142857143 1.82412396357211 0.0100566400968668 0.167034506608897 GO:0005159 insulin-like growth factor receptor binding 4/1051 16/18639 0.25 4.43363463368221 0.0106035364235711 0.170781200276607 GO:0008142 oxysterol binding 4/1051 16/18639 0.25 4.43363463368221 0.0106035364235711 0.170781200276607 GO:0019825 oxygen binding 6/1051 34/18639 0.176470588235294 3.12962444730509 0.0109628755496926 0.173933383721242 GO:0019199 transmembrane receptor protein kinase activity 10/1051 78/18639 0.128205128205128 2.2736587865037 0.0120201799995907 0.187903696170072 GO:0003924 GTPase activity 29/1051 331/18639 0.0876132930513595 1.55378132177382 0.0126069917150973 0.19422075642244 GO:1990841 promoter-specific chromatin binding 9/1051 68/18639 0.132352941176471 2.34721833547882 0.0137604318786018 0.208961986956482 GO:0140375 immune receptor activity 16/1051 156/18639 0.102564102564103 1.81892702920296 0.0150411535558773 0.213157772127905 GO:0005522 profilin binding 3/1051 10/18639 0.3 5.32036156041865 0.0159121988516499 0.213157772127905 GO:0008239 dipeptidyl-peptidase activity 3/1051 10/18639 0.3 5.32036156041865 0.0159121988516499 0.213157772127905 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 3/1051 10/18639 0.3 5.32036156041865 0.0159121988516499 0.213157772127905 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 3/1051 10/18639 0.3 5.32036156041865 0.0159121988516499 0.213157772127905 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 3/1051 10/18639 0.3 5.32036156041865 0.0159121988516499 0.213157772127905 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 3/1051 10/18639 0.3 5.32036156041865 0.0159121988516499 0.213157772127905 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 3/1051 10/18639 0.3 5.32036156041865 0.0159121988516499 0.213157772127905 GO:0005044 scavenger receptor activity 5/1051 27/18639 0.185185185185185 3.28417380272756 0.0161601495115482 0.213157772127905 GO:0008237 metallopeptidase activity 18/1051 184/18639 0.0978260869565217 1.73490050883217 0.0162311983502823 0.213157772127905 GO:0003746 translation elongation factor activity 4/1051 18/18639 0.222222222222222 3.94100856327307 0.0163002219053261 0.213157772127905 GO:0097110 scaffold protein binding 9/1051 70/18639 0.128571428571429 2.28015495446514 0.0164430266363953 0.213157772127905 GO:0001664 G protein-coupled receptor binding 26/1051 297/18639 0.0875420875420875 1.55251852492576 0.0176354729049757 0.22586153852999 GO:0001540 amyloid-beta binding 10/1051 83/18639 0.120481927710843 2.13669138972636 0.0180856982552647 0.226177614651134 GO:0008135 translation factor activity, RNA binding 10/1051 83/18639 0.120481927710843 2.13669138972636 0.0180856982552647 0.226177614651134 GO:0019001 guanyl nucleotide binding 33/1051 400/18639 0.0825 1.46309942911513 0.0186190369646338 0.227494670039147 GO:0032561 guanyl ribonucleotide binding 33/1051 400/18639 0.0825 1.46309942911513 0.0186190369646338 0.227494670039147 GO:0004714 transmembrane receptor protein tyrosine kinase activity 8/1051 60/18639 0.133333333333333 2.36460513796384 0.0188459467966562 0.227650470964154 GO:0004896 cytokine receptor activity 11/1051 96/18639 0.114583333333333 2.03208254043768 0.0191690403453552 0.22895157176531 GO:0180051 translation factor activity 10/1051 84/18639 0.119047619047619 2.11125458746772 0.0195286252206138 0.230654762327917 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 3/1051 11/18639 0.272727272727273 4.83669232765332 0.0209757272032646 0.239105057279454 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 3/1051 11/18639 0.272727272727273 4.83669232765332 0.0209757272032646 0.239105057279454 GO:0004222 metalloendopeptidase activity 12/1051 110/18639 0.109090909090909 1.93467693106133 0.0211430384483277 0.239105057279454 GO:0044325 transmembrane transporter binding 14/1051 136/18639 0.102941176470588 1.82561426092797 0.021368749239462 0.239105057279454 GO:0140789 histone phosphatase activity 14/1051 136/18639 0.102941176470588 1.82561426092797 0.021368749239462 0.239105057279454 GO:0043021 ribonucleoprotein complex binding 17/1051 177/18639 0.096045197740113 1.70331726039768 0.0224405699278722 0.248373419251786 GO:0016209 antioxidant activity 10/1051 86/18639 0.116279069767442 2.06215564357312 0.022664366573305 0.248373419251786 GO:0005010 insulin-like growth factor receptor activity 7/1051 51/18639 0.137254901960784 2.43415234790396 0.0235375178344356 0.251989366941911 GO:0005021 vascular endothelial growth factor receptor activity 7/1051 51/18639 0.137254901960784 2.43415234790396 0.0235375178344356 0.251989366941911 GO:0005525 GTP binding 31/1051 378/18639 0.082010582010582 1.45441982692221 0.0237054907753444 0.251989366941911 GO:0005200 structural constituent of cytoskeleton 12/1051 112/18639 0.107142857142857 1.90012912872095 0.0239936487744204 0.252527214328801 GO:0033612 receptor serine/threonine kinase binding 5/1051 30/18639 0.166666666666667 2.9557564224548 0.0248345332899021 0.258814793011431 GO:0070679 inositol 1,4,5 trisphosphate binding 3/1051 12/18639 0.25 4.43363463368221 0.0268163083632582 0.270971371854959 GO:0097371 MDM2/MDM4 family protein binding 3/1051 12/18639 0.25 4.43363463368221 0.0268163083632582 0.270971371854959 GO:0141221 histone deacetylase activity, hydrolytic mechanism 3/1051 12/18639 0.25 4.43363463368221 0.0268163083632582 0.270971371854959 GO:0042826 histone deacetylase binding 13/1051 127/18639 0.102362204724409 1.81534646418484 0.0270206636092433 0.270971371854959 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 10/1051 89/18639 0.112359550561798 1.99264477918301 0.0280284279733566 0.275872397552575 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 10/1051 89/18639 0.112359550561798 1.99264477918301 0.0280284279733566 0.275872397552575 GO:0020037 heme binding 14/1051 142/18639 0.0985915492957746 1.74847563018453 0.0296607573861407 0.289260413774932 GO:0140793 histone H2AXY142 phosphatase activity 10/1051 90/18639 0.111111111111111 1.97050428163654 0.0300016735143644 0.289925263143358 GO:0015485 cholesterol binding 7/1051 54/18639 0.12962962962963 2.29892166190929 0.0311712510082029 0.298513872267745 GO:0140666 annealing activity 3/1051 13/18639 0.230769230769231 4.09258581570665 0.033430679515555 0.317292967187812 GO:0019207 kinase regulator activity 24/1051 287/18639 0.0836236933797909 1.48302761266025 0.0351388133564261 0.330553615910451 GO:0008013 beta-catenin binding 11/1051 106/18639 0.10377358490566 1.84037664039639 0.0365799254787787 0.337416393370793 GO:0032934 sterol binding 8/1051 68/18639 0.117647058823529 2.08641629820339 0.0368610416811274 0.337416393370793 GO:0005158 insulin receptor binding 4/1051 23/18639 0.173913043478261 3.08426757125719 0.03777286059372 0.337416393370793 GO:0017134 fibroblast growth factor binding 4/1051 23/18639 0.173913043478261 3.08426757125719 0.03777286059372 0.337416393370793 GO:0031681 G-protein beta-subunit binding 4/1051 23/18639 0.173913043478261 3.08426757125719 0.03777286059372 0.337416393370793 GO:0070577 lysine-acetylated histone binding 4/1051 23/18639 0.173913043478261 3.08426757125719 0.03777286059372 0.337416393370793 GO:0015035 protein-disulfide reductase activity 5/1051 34/18639 0.147058823529412 2.60802037275424 0.0403581315575549 0.355488498075602 GO:0008083 growth factor activity 15/1051 162/18639 0.0925925925925926 1.64208690136378 0.0404648243340995 0.355488498075602 GO:0005540 hyaluronic acid binding 4/1051 24/18639 0.166666666666667 2.9557564224548 0.0433713922226357 0.373335211037002 GO:0140033 acetylation-dependent protein binding 4/1051 24/18639 0.166666666666667 2.9557564224548 0.0433713922226357 0.373335211037002 GO:0002020 protease binding 13/1051 136/18639 0.0955882352941176 1.69521324229026 0.0435499211369598 0.373335211037002 GO:0004857 enzyme inhibitor activity 32/1051 416/18639 0.0769230769230769 1.36419527190222 0.0466700484855697 0.396882092321284 GO:0046906 tetrapyrrole binding 14/1051 152/18639 0.0921052631578947 1.63344433872502 0.0483545823259494 0.398407735170775 GO:0051015 actin filament binding 18/1051 209/18639 0.0861244019138756 1.5273765245221 0.0488984894135244 0.398407735170775 GO:0004559 alpha-mannosidase activity 3/1051 15/18639 0.2 3.54690770694577 0.0489302371659649 0.398407735170775 GO:0141050 histone H3K deacetylase activity 3/1051 15/18639 0.2 3.54690770694577 0.0489302371659649 0.398407735170775 GO:0141051 histone H4K deacetylase activity 3/1051 15/18639 0.2 3.54690770694577 0.0489302371659649 0.398407735170775 GO:0019211 phosphatase activator activity 4/1051 25/18639 0.16 2.83752616555661 0.0494098407031571 0.398407735170775 GO:0044390 ubiquitin-like protein conjugating enzyme binding 5/1051 36/18639 0.138888888888889 2.46313035204567 0.0499087709652017 0.398407735170775 GO:0045505 dynein intermediate chain binding 5/1051 36/18639 0.138888888888889 2.46313035204567 0.0499087709652017 0.398407735170775 GO:0001098 basal transcription machinery binding 7/1051 60/18639 0.116666666666667 2.06902949571836 0.0510332302675891 0.398407735170775 GO:0001099 basal RNA polymerase II transcription machinery binding 7/1051 60/18639 0.116666666666667 2.06902949571836 0.0510332302675891 0.398407735170775 GO:0038187 pattern recognition receptor activity 6/1051 48/18639 0.125 2.2168173168411 0.0516664830134133 0.398407735170775 GO:0043394 proteoglycan binding 5/1051 37/18639 0.135135135135135 2.39655926144984 0.0551398467376433 0.398407735170775 GO:0005096 GTPase activator activity 22/1051 271/18639 0.0811808118081181 1.43970423529164 0.0551819956053973 0.398407735170775 GO:0070412 R-SMAD binding 4/1051 26/18639 0.153846153846154 2.72839054380444 0.0558857474288694 0.398407735170775 GO:0005004 GPI-linked ephrin receptor activity 6/1051 49/18639 0.122448979591837 2.17157614710965 0.0561923040167442 0.398407735170775 GO:0005008 hepatocyte growth factor receptor activity 6/1051 49/18639 0.122448979591837 2.17157614710965 0.0561923040167442 0.398407735170775 GO:0005009 insulin receptor activity 6/1051 49/18639 0.122448979591837 2.17157614710965 0.0561923040167442 0.398407735170775 GO:0005011 macrophage colony-stimulating factor receptor activity 6/1051 49/18639 0.122448979591837 2.17157614710965 0.0561923040167442 0.398407735170775 GO:0005018 platelet-derived growth factor alpha-receptor activity 6/1051 49/18639 0.122448979591837 2.17157614710965 0.0561923040167442 0.398407735170775 GO:0005020 stem cell factor receptor activity 6/1051 49/18639 0.122448979591837 2.17157614710965 0.0561923040167442 0.398407735170775 GO:0008288 boss receptor activity 6/1051 49/18639 0.122448979591837 2.17157614710965 0.0561923040167442 0.398407735170775 GO:0036332 placental growth factor receptor activity 6/1051 49/18639 0.122448979591837 2.17157614710965 0.0561923040167442 0.398407735170775 GO:0038062 protein tyrosine kinase collagen receptor activity 6/1051 49/18639 0.122448979591837 2.17157614710965 0.0561923040167442 0.398407735170775 GO:0060175 brain-derived neurotrophic factor receptor activity 6/1051 49/18639 0.122448979591837 2.17157614710965 0.0561923040167442 0.398407735170775 GO:0031491 nucleosome binding 8/1051 74/18639 0.108108108108108 1.91724740915987 0.0562193417456408 0.398407735170775 GO:0005324 long-chain fatty acid transmembrane transporter activity 3/1051 16/18639 0.1875 3.32522597526166 0.0577748604142097 0.398796601430551 GO:0005521 lamin binding 3/1051 16/18639 0.1875 3.32522597526166 0.0577748604142097 0.398796601430551 GO:0015923 mannosidase activity 3/1051 16/18639 0.1875 3.32522597526166 0.0577748604142097 0.398796601430551 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 3/1051 16/18639 0.1875 3.32522597526166 0.0577748604142097 0.398796601430551 GO:0005109 frizzled binding 5/1051 38/18639 0.131578947368421 2.33349191246432 0.0606751921577454 0.407477333542585 GO:0005006 epidermal growth factor receptor activity 6/1051 50/18639 0.12 2.12814462416746 0.0609491025712804 0.407477333542585 GO:0005007 fibroblast growth factor receptor activity 6/1051 50/18639 0.12 2.12814462416746 0.0609491025712804 0.407477333542585 GO:0005017 platelet-derived growth factor receptor activity 6/1051 50/18639 0.12 2.12814462416746 0.0609491025712804 0.407477333542585 GO:0005019 platelet-derived growth factor beta-receptor activity 6/1051 50/18639 0.12 2.12814462416746 0.0609491025712804 0.407477333542585 GO:0005030 neurotrophin receptor activity 6/1051 51/18639 0.117647058823529 2.08641629820339 0.0659373138695264 0.431053996737839 GO:0031072 heat shock protein binding 12/1051 131/18639 0.0916030534351145 1.62453788104386 0.0663161716881792 0.431053996737839 GO:0019210 kinase inhibitor activity 9/1051 90/18639 0.1 1.77345385347288 0.0668406401724627 0.431053996737839 GO:0015278 intracellularly gated calcium channel activity 3/1051 17/18639 0.176470588235294 3.12962444730509 0.0673141707041216 0.431053996737839 GO:0030169 low-density lipoprotein particle binding 3/1051 17/18639 0.176470588235294 3.12962444730509 0.0673141707041216 0.431053996737839 GO:0032183 SUMO binding 3/1051 17/18639 0.176470588235294 3.12962444730509 0.0673141707041216 0.431053996737839 GO:0046965 nuclear retinoid X receptor binding 3/1051 17/18639 0.176470588235294 3.12962444730509 0.0673141707041216 0.431053996737839 GO:0046625 sphingolipid binding 4/1051 28/18639 0.142857142857143 2.53350550496126 0.0701297178619901 0.446394551420931 GO:0019902 phosphatase binding 16/1051 190/18639 0.0842105263157895 1.49343482397716 0.071174402875724 0.450347561052944 GO:0015036 disulfide oxidoreductase activity 5/1051 40/18639 0.125 2.2168173168411 0.072653937178057 0.456450306171739 GO:0030246 carbohydrate binding 22/1051 280/18639 0.0785714285714286 1.39342802772869 0.0729976971300053 0.456450306171739 GO:0005003 ephrin receptor activity 6/1051 53/18639 0.113207547169811 2.00768360770515 0.0766068977288739 0.468006507389615 GO:0005005 transmembrane-ephrin receptor activity 6/1051 53/18639 0.113207547169811 2.00768360770515 0.0766068977288739 0.468006507389615 GO:0016860 intramolecular oxidoreductase activity 6/1051 53/18639 0.113207547169811 2.00768360770515 0.0766068977288739 0.468006507389615 GO:0038064 collagen receptor activity 6/1051 53/18639 0.113207547169811 2.00768360770515 0.0766068977288739 0.468006507389615 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 3/1051 18/18639 0.166666666666667 2.9557564224548 0.0775169604638807 0.468184823710825 GO:0070628 proteasome binding 3/1051 18/18639 0.166666666666667 2.9557564224548 0.0775169604638807 0.468184823710825 GO:0016877 ligase activity, forming carbon-sulfur bonds 5/1051 41/18639 0.121951219512195 2.1627486017962 0.0790925588823745 0.472333652202046 GO:0042169 SH2 domain binding 5/1051 41/18639 0.121951219512195 2.1627486017962 0.0790925588823745 0.472333652202046 GO:0051082 unfolded protein binding 11/1051 121/18639 0.0909090909090909 1.61223077588444 0.0797124327486281 0.473376067104981 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 6/1051 54/18639 0.111111111111111 1.97050428163654 0.0822863535689578 0.48139481298059 GO:0016500 protein-hormone receptor activity 7/1051 67/18639 0.104477611940299 1.85286223497167 0.082489561922131 0.48139481298059 GO:0005496 steroid binding 10/1051 108/18639 0.0925925925925926 1.64208690136378 0.0835614416020279 0.48139481298059 GO:0019887 protein kinase regulator activity 20/1051 255/18639 0.0784313725490196 1.39094419880226 0.0853661032407736 0.48139481298059 GO:0001618 virus receptor activity 8/1051 81/18639 0.0987654320987654 1.7515593614547 0.0857321337859312 0.48139481298059 GO:0008307 structural constituent of muscle 5/1051 42/18639 0.119047619047619 2.11125458746772 0.0858259742951354 0.48139481298059 GO:0031492 nucleosomal DNA binding 5/1051 42/18639 0.119047619047619 2.11125458746772 0.0858259742951354 0.48139481298059 GO:0051879 Hsp90 protein binding 5/1051 42/18639 0.119047619047619 2.11125458746772 0.0858259742951354 0.48139481298059 GO:0001968 fibronectin binding 4/1051 30/18639 0.133333333333333 2.36460513796384 0.0860442280962484 0.48139481298059 GO:0035925 mRNA 3'-UTR AU-rich region binding 4/1051 30/18639 0.133333333333333 2.36460513796384 0.0860442280962484 0.48139481298059 GO:0048019 receptor antagonist activity 4/1051 30/18639 0.133333333333333 2.36460513796384 0.0860442280962484 0.48139481298059 GO:0042578 phosphoric ester hydrolase activity 27/1051 363/18639 0.0743801652892562 1.31909790754181 0.0867344732603419 0.481615879822819 GO:0003756 protein disulfide isomerase activity 3/1051 19/18639 0.157894736842105 2.80019029495718 0.0883491030719189 0.481615879822819 GO:0015245 fatty acid transmembrane transporter activity 3/1051 19/18639 0.157894736842105 2.80019029495718 0.0883491030719189 0.481615879822819 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 3/1051 19/18639 0.157894736842105 2.80019029495718 0.0883491030719189 0.481615879822819 GO:0097001 ceramide binding 3/1051 19/18639 0.157894736842105 2.80019029495718 0.0883491030719189 0.481615879822819 GO:0140272 exogenous protein binding 8/1051 82/18639 0.0975609756097561 1.73019888143696 0.0905685648888534 0.491195839167608 GO:0016791 phosphatase activity 21/1051 273/18639 0.0769230769230769 1.36419527190222 0.092607907299462 0.498480316981791 GO:0008200 ion channel inhibitor activity 5/1051 43/18639 0.116279069767442 2.06215564357312 0.0928495792684804 0.498480316981791 GO:0016878 acid-thiol ligase activity 4/1051 31/18639 0.129032258064516 2.28832755286824 0.0946021314619161 0.505337013789029 GO:0016505 peptidase activator activity involved in apoptotic process 3/1051 20/18639 0.15 2.66018078020932 0.0997742177122818 0.519355695913224 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 3/1051 20/18639 0.15 2.66018078020932 0.0997742177122818 0.519355695913224 GO:0043024 ribosomal small subunit binding 3/1051 20/18639 0.15 2.66018078020932 0.0997742177122818 0.519355695913224 GO:0140939 histone H4 methyltransferase activity 3/1051 20/18639 0.15 2.66018078020932 0.0997742177122818 0.519355695913224 GO:0016248 channel inhibitor activity 5/1051 44/18639 0.113636363636364 2.01528846985555 0.100157965815815 0.519355695913224 GO:0030547 signaling receptor inhibitor activity 5/1051 44/18639 0.113636363636364 2.01528846985555 0.100157965815815 0.519355695913224 GO:0004860 protein kinase inhibitor activity 8/1051 84/18639 0.0952380952380952 1.68900366997417 0.100703132127303 0.51964771578312 GO:0003680 minor groove of adenine-thymine-rich DNA binding 2/1051 10/18639 0.2 3.54690770694577 0.10583447689 0.520842819139213 GO:0004955 prostaglandin receptor activity 2/1051 10/18639 0.2 3.54690770694577 0.10583447689 0.520842819139213 GO:0005131 growth hormone receptor binding 2/1051 10/18639 0.2 3.54690770694577 0.10583447689 0.520842819139213 GO:0015279 store-operated calcium channel activity 2/1051 10/18639 0.2 3.54690770694577 0.10583447689 0.520842819139213 GO:0032356 oxidized DNA binding 2/1051 10/18639 0.2 3.54690770694577 0.10583447689 0.520842819139213 GO:0047429 nucleoside triphosphate diphosphatase activity 2/1051 10/18639 0.2 3.54690770694577 0.10583447689 0.520842819139213 GO:0070097 delta-catenin binding 2/1051 10/18639 0.2 3.54690770694577 0.10583447689 0.520842819139213 GO:0070513 death domain binding 2/1051 10/18639 0.2 3.54690770694577 0.10583447689 0.520842819139213 GO:0140940 histone H2A methyltransferase activity 2/1051 10/18639 0.2 3.54690770694577 0.10583447689 0.520842819139213 GO:1990259 histone H2AQ104 methyltransferase activity 2/1051 10/18639 0.2 3.54690770694577 0.10583447689 0.520842819139213 GO:0008009 chemokine activity 5/1051 45/18639 0.111111111111111 1.97050428163654 0.107744971089871 0.525380294809785 GO:0141110 transporter inhibitor activity 5/1051 45/18639 0.111111111111111 1.97050428163654 0.107744971089871 0.525380294809785 GO:0005248 voltage-gated sodium channel activity 3/1051 21/18639 0.142857142857143 2.53350550496126 0.111754255388599 0.538902101907018 GO:0072542 protein phosphatase activator activity 3/1051 21/18639 0.142857142857143 2.53350550496126 0.111754255388599 0.538902101907018 GO:0035591 signaling adaptor activity 11/1051 129/18639 0.0852713178294574 1.51224747195362 0.112038913002306 0.538902101907018 GO:0004879 nuclear receptor activity 6/1051 59/18639 0.101694915254237 1.80351239336225 0.114044842861523 0.542162158806317 GO:0070888 E-box binding 6/1051 59/18639 0.101694915254237 1.80351239336225 0.114044842861523 0.542162158806317 GO:0003714 transcription corepressor activity 16/1051 204/18639 0.0784313725490196 1.39094419880226 0.114246776644041 0.542162158806317 GO:0043539 protein serine/threonine kinase activator activity 7/1051 73/18639 0.0958904109589041 1.70057218826167 0.116630849409449 0.547717237025083 GO:0098531 ligand-modulated transcription factor activity 6/1051 60/18639 0.1 1.77345385347288 0.121046133149738 0.547717237025083 GO:0030695 GTPase regulator activity 34/1051 489/18639 0.0695296523517382 1.2330762989382 0.121227155216024 0.547717237025083 GO:0060589 nucleoside-triphosphatase regulator activity 34/1051 490/18639 0.0693877551020408 1.23055981669547 0.123586880018649 0.547717237025083 GO:0004407 histone deacetylase activity 3/1051 22/18639 0.136363636363636 2.41834616382666 0.124250013600603 0.547717237025083 GO:0033558 protein lysine deacetylase activity 3/1051 22/18639 0.136363636363636 2.41834616382666 0.124250013600603 0.547717237025083 GO:0061133 endopeptidase activator activity 3/1051 22/18639 0.136363636363636 2.41834616382666 0.124250013600603 0.547717237025083 GO:0140517 protein-RNA adaptor activity 3/1051 22/18639 0.136363636363636 2.41834616382666 0.124250013600603 0.547717237025083 GO:0003953 NAD+ nucleosidase activity 2/1051 11/18639 0.181818181818182 3.22446155176888 0.124691976820386 0.547717237025083 GO:0004954 prostanoid receptor activity 2/1051 11/18639 0.181818181818182 3.22446155176888 0.124691976820386 0.547717237025083 GO:0008046 axon guidance receptor activity 2/1051 11/18639 0.181818181818182 3.22446155176888 0.124691976820386 0.547717237025083 GO:0010854 adenylate cyclase regulator activity 2/1051 11/18639 0.181818181818182 3.22446155176888 0.124691976820386 0.547717237025083 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 2/1051 11/18639 0.181818181818182 3.22446155176888 0.124691976820386 0.547717237025083 GO:0019864 IgG binding 2/1051 11/18639 0.181818181818182 3.22446155176888 0.124691976820386 0.547717237025083 GO:0034713 type I transforming growth factor beta receptor binding 2/1051 11/18639 0.181818181818182 3.22446155176888 0.124691976820386 0.547717237025083 GO:0050998 nitric-oxide synthase binding 2/1051 11/18639 0.181818181818182 3.22446155176888 0.124691976820386 0.547717237025083 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 2/1051 11/18639 0.181818181818182 3.22446155176888 0.124691976820386 0.547717237025083 GO:0140031 phosphorylation-dependent protein binding 2/1051 11/18639 0.181818181818182 3.22446155176888 0.124691976820386 0.547717237025083 GO:0003779 actin binding 31/1051 443/18639 0.0699774266365688 1.24101736924739 0.126411521693127 0.552985380904502 GO:0034061 DNA polymerase activity 4/1051 35/18639 0.114285714285714 2.02680440396901 0.132526792907031 0.577360577295793 GO:0003887 DNA-directed DNA polymerase activity 3/1051 23/18639 0.130434782608696 2.31320067844289 0.137221586551636 0.595373659201587 GO:0005049 nuclear export signal receptor activity 2/1051 12/18639 0.166666666666667 2.9557564224548 0.144267110511811 0.599046634664278 GO:0008179 adenylate cyclase binding 2/1051 12/18639 0.166666666666667 2.9557564224548 0.144267110511811 0.599046634664278 GO:0016208 AMP binding 2/1051 12/18639 0.166666666666667 2.9557564224548 0.144267110511811 0.599046634664278 GO:0035014 phosphatidylinositol 3-kinase regulator activity 2/1051 12/18639 0.166666666666667 2.9557564224548 0.144267110511811 0.599046634664278 GO:0035497 cAMP response element binding 2/1051 12/18639 0.166666666666667 2.9557564224548 0.144267110511811 0.599046634664278 GO:0036009 protein-glutamine N-methyltransferase activity 2/1051 12/18639 0.166666666666667 2.9557564224548 0.144267110511811 0.599046634664278 GO:0045295 gamma-catenin binding 2/1051 12/18639 0.166666666666667 2.9557564224548 0.144267110511811 0.599046634664278 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 2/1051 12/18639 0.166666666666667 2.9557564224548 0.144267110511811 0.599046634664278 GO:0070410 co-SMAD binding 2/1051 12/18639 0.166666666666667 2.9557564224548 0.144267110511811 0.599046634664278 GO:0097677 STAT family protein binding 2/1051 12/18639 0.166666666666667 2.9557564224548 0.144267110511811 0.599046634664278 GO:1990247 N6-methyladenosine-containing RNA reader activity 2/1051 12/18639 0.166666666666667 2.9557564224548 0.144267110511811 0.599046634664278 GO:0005126 cytokine receptor binding 20/1051 275/18639 0.0727272727272727 1.28978462070755 0.146786476611401 0.607136282637818 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 3/1051 24/18639 0.125 2.2168173168411 0.150628757170064 0.613480340504898 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 3/1051 24/18639 0.125 2.2168173168411 0.150628757170064 0.613480340504898 GO:0035035 histone acetyltransferase binding 3/1051 24/18639 0.125 2.2168173168411 0.150628757170064 0.613480340504898 GO:0050431 transforming growth factor beta binding 3/1051 24/18639 0.125 2.2168173168411 0.150628757170064 0.613480340504898 GO:0042805 actinin binding 4/1051 37/18639 0.108108108108108 1.91724740915987 0.153486069760319 0.6227316494474 GO:0003743 translation initiation factor activity 5/1051 51/18639 0.0980392156862745 1.73868024850283 0.158690612794241 0.641399701141742 GO:0008035 high-density lipoprotein particle binding 2/1051 13/18639 0.153846153846154 2.72839054380444 0.164419188874767 0.64261217242515 GO:0035325 Toll-like receptor binding 2/1051 13/18639 0.153846153846154 2.72839054380444 0.164419188874767 0.64261217242515 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 2/1051 13/18639 0.153846153846154 2.72839054380444 0.164419188874767 0.64261217242515 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 2/1051 13/18639 0.153846153846154 2.72839054380444 0.164419188874767 0.64261217242515 GO:0097157 pre-mRNA intronic binding 2/1051 13/18639 0.153846153846154 2.72839054380444 0.164419188874767 0.64261217242515 GO:0005537 D-mannose binding 3/1051 25/18639 0.12 2.12814462416746 0.164431336688279 0.64261217242515 GO:0015645 fatty acid ligase activity 3/1051 25/18639 0.12 2.12814462416746 0.164431336688279 0.64261217242515 GO:0042974 nuclear retinoic acid receptor binding 3/1051 25/18639 0.12 2.12814462416746 0.164431336688279 0.64261217242515 GO:0120515 fatty acid-CoA ligase activity 3/1051 25/18639 0.12 2.12814462416746 0.164431336688279 0.64261217242515 GO:0004867 serine-type endopeptidase inhibitor activity 8/1051 95/18639 0.0842105263157895 1.49343482397716 0.16693199194389 0.649995265334635 GO:0042054 histone methyltransferase activity 6/1051 67/18639 0.0895522388059701 1.58816762997572 0.175546117658447 0.675589298288719 GO:0051020 GTPase binding 22/1051 315/18639 0.0698412698412698 1.23860269131439 0.176834470395156 0.675589298288719 GO:0017046 peptide hormone binding 5/1051 53/18639 0.0943396226415094 1.67306967308763 0.177523117847228 0.675589298288719 GO:0051018 protein kinase A binding 5/1051 53/18639 0.0943396226415094 1.67306967308763 0.177523117847228 0.675589298288719 GO:0004112 cyclic-nucleotide phosphodiesterase activity 3/1051 26/18639 0.115384615384615 2.04629290785333 0.178589457026463 0.675589298288719 GO:0030247 polysaccharide binding 3/1051 26/18639 0.115384615384615 2.04629290785333 0.178589457026463 0.675589298288719 GO:0050750 low-density lipoprotein particle receptor binding 3/1051 26/18639 0.115384615384615 2.04629290785333 0.178589457026463 0.675589298288719 GO:0070006 metalloaminopeptidase activity 3/1051 26/18639 0.115384615384615 2.04629290785333 0.178589457026463 0.675589298288719 GO:0043022 ribosome binding 9/1051 112/18639 0.0803571428571429 1.42509684654071 0.180732740864381 0.679308354213804 GO:0005161 platelet-derived growth factor receptor binding 2/1051 14/18639 0.142857142857143 2.53350550496126 0.185021080755354 0.679308354213804 GO:0015926 glucosidase activity 2/1051 14/18639 0.142857142857143 2.53350550496126 0.185021080755354 0.679308354213804 GO:0019763 immunoglobulin receptor activity 2/1051 14/18639 0.142857142857143 2.53350550496126 0.185021080755354 0.679308354213804 GO:0031404 chloride ion binding 2/1051 14/18639 0.142857142857143 2.53350550496126 0.185021080755354 0.679308354213804 GO:0034236 protein kinase A catalytic subunit binding 2/1051 14/18639 0.142857142857143 2.53350550496126 0.185021080755354 0.679308354213804 GO:0042043 neurexin family protein binding 2/1051 14/18639 0.142857142857143 2.53350550496126 0.185021080755354 0.679308354213804 GO:0042813 Wnt receptor activity 2/1051 14/18639 0.142857142857143 2.53350550496126 0.185021080755354 0.679308354213804 GO:0004177 aminopeptidase activity 4/1051 40/18639 0.1 1.77345385347288 0.187030178895919 0.679308354213804 GO:0030331 nuclear estrogen receptor binding 4/1051 40/18639 0.1 1.77345385347288 0.187030178895919 0.679308354213804 GO:0071855 neuropeptide receptor binding 4/1051 40/18639 0.1 1.77345385347288 0.187030178895919 0.679308354213804 GO:0003925 G protein activity 5/1051 54/18639 0.0925925925925926 1.64208690136378 0.18724115501848 0.679308354213804 GO:0005104 fibroblast growth factor receptor binding 3/1051 27/18639 0.111111111111111 1.97050428163654 0.193063820771438 0.693333923919048 GO:0015252 proton channel activity 3/1051 27/18639 0.111111111111111 1.97050428163654 0.193063820771438 0.693333923919048 GO:0016405 CoA-ligase activity 3/1051 27/18639 0.111111111111111 1.97050428163654 0.193063820771438 0.693333923919048 GO:0051117 ATPase binding 7/1051 84/18639 0.0833333333333333 1.4778782112274 0.194831313258834 0.697325542067813 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 32/1051 484/18639 0.0661157024793388 1.1725314733705 0.197927384774708 0.70602956381045 GO:0001221 transcription coregulator binding 9/1051 115/18639 0.0782608695652174 1.38792040706573 0.200705636691157 0.713545457534113 GO:0008028 monocarboxylic acid transmembrane transporter activity 6/1051 70/18639 0.0857142857142857 1.52010330297676 0.201510141100989 0.714017599967837 GO:0005319 lipid transporter activity 13/1051 178/18639 0.0730337078651685 1.29521910646896 0.205492292450496 0.717814741091873 GO:0000774 adenyl-nucleotide exchange factor activity 2/1051 15/18639 0.133333333333333 2.36460513796384 0.20595813361526 0.717814741091873 GO:0004953 icosanoid receptor activity 2/1051 15/18639 0.133333333333333 2.36460513796384 0.20595813361526 0.717814741091873 GO:0005041 low-density lipoprotein particle receptor activity 2/1051 15/18639 0.133333333333333 2.36460513796384 0.20595813361526 0.717814741091873 GO:0050780 dopamine receptor binding 2/1051 15/18639 0.133333333333333 2.36460513796384 0.20595813361526 0.717814741091873 GO:0170055 lipid transmembrane transporter activity 5/1051 56/18639 0.0892857142857143 1.58344094060079 0.207226333524317 0.719874485412905 GO:0042056 chemoattractant activity 4/1051 42/18639 0.0952380952380952 1.68900366997417 0.210580493578132 0.726776184005047 GO:0048487 beta-tubulin binding 4/1051 42/18639 0.0952380952380952 1.68900366997417 0.210580493578132 0.726776184005047 GO:1990782 protein tyrosine kinase binding 9/1051 117/18639 0.0769230769230769 1.36419527190222 0.214509327041935 0.737939853221933 GO:0008238 exopeptidase activity 8/1051 102/18639 0.0784313725490196 1.39094419880226 0.217238191200334 0.744916765309531 GO:0008081 phosphoric diester hydrolase activity 7/1051 87/18639 0.0804597701149425 1.42691689359887 0.21911074047993 0.748921920032685 GO:0001216 DNA-binding transcription activator activity 32/1051 491/18639 0.065173116089613 1.1558151387196 0.221137675902059 0.752464233028301 GO:0048156 tau protein binding 4/1051 43/18639 0.0930232558139535 1.6497245148585 0.222655459148353 0.752464233028301 GO:0099604 ligand-gated calcium channel activity 3/1051 29/18639 0.103448275862069 1.83460743462712 0.222808179774245 0.752464233028301 GO:0005024 transforming growth factor beta receptor activity 2/1051 16/18639 0.125 2.2168173168411 0.227127172643981 0.752464233028301 GO:0015562 efflux transmembrane transporter activity 2/1051 16/18639 0.125 2.2168173168411 0.227127172643981 0.752464233028301 GO:0017070 U6 snRNA binding 2/1051 16/18639 0.125 2.2168173168411 0.227127172643981 0.752464233028301 GO:0019841 retinol binding 2/1051 16/18639 0.125 2.2168173168411 0.227127172643981 0.752464233028301 GO:0031435 mitogen-activated protein kinase kinase kinase binding 2/1051 16/18639 0.125 2.2168173168411 0.227127172643981 0.752464233028301 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 2/1051 16/18639 0.125 2.2168173168411 0.227127172643981 0.752464233028301 GO:0000287 magnesium ion binding 16/1051 230/18639 0.0695652173913043 1.23370702850288 0.227225793793118 0.752464233028301 GO:0016874 ligase activity 12/1051 167/18639 0.0718562874251497 1.27433809830387 0.233464294715516 0.770692088320827 GO:0001046 core promoter sequence-specific DNA binding 4/1051 44/18639 0.0909090909090909 1.61223077588444 0.234905208481607 0.770692088320827 GO:0001223 transcription coactivator binding 4/1051 44/18639 0.0909090909090909 1.61223077588444 0.234905208481607 0.770692088320827 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 3/1051 30/18639 0.1 1.77345385347288 0.238004174405133 0.771661081333516 GO:0008106 alcohol dehydrogenase (NADP+) activity 3/1051 30/18639 0.1 1.77345385347288 0.238004174405133 0.771661081333516 GO:0031210 phosphatidylcholine binding 3/1051 30/18639 0.1 1.77345385347288 0.238004174405133 0.771661081333516 GO:0048029 monosaccharide binding 6/1051 74/18639 0.0810810810810811 1.43793555686991 0.23810426592417 0.771661081333516 GO:0061135 endopeptidase regulator activity 13/1051 184/18639 0.0706521739130435 1.25298370082323 0.239545561970329 0.773972438828144 GO:0016922 nuclear receptor binding 10/1051 137/18639 0.072992700729927 1.29449186384882 0.244796587774311 0.788541735769979 GO:0019003 GDP binding 6/1051 75/18639 0.08 1.41876308277831 0.247554653626061 0.793054096082568 GO:0031267 small GTPase binding 19/1051 283/18639 0.0671378091872792 1.19065806416907 0.247808329331631 0.793054096082568 GO:0048038 quinone binding 2/1051 17/18639 0.117647058823529 2.08641629820339 0.248435572902629 0.793054096082568 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 7/1051 91/18639 0.0769230769230769 1.36419527190222 0.253023341772957 0.803972853085321 GO:0070325 lipoprotein particle receptor binding 3/1051 31/18639 0.0967741935483871 1.71624566465118 0.253368679006192 0.803972853085321 GO:0051536 iron-sulfur cluster binding 6/1051 76/18639 0.0789473684210526 1.40009514747859 0.257110091694524 0.805611866919365 GO:0070851 growth factor receptor binding 10/1051 139/18639 0.0719424460431655 1.27586608163517 0.258716751922594 0.805611866919365 GO:0019905 syntaxin binding 5/1051 61/18639 0.0819672131147541 1.45365069956794 0.259865150565049 0.805611866919365 GO:0046982 protein heterodimerization activity 24/1051 369/18639 0.0650406504065041 1.15346592095797 0.263009312569852 0.805611866919365 GO:0004713 protein tyrosine kinase activity 10/1051 140/18639 0.0714285714285714 1.26675275248063 0.265773388024222 0.805611866919365 GO:0051540 metal cluster binding 6/1051 77/18639 0.0779220779220779 1.38191209361523 0.266762644873029 0.805611866919365 GO:0022884 macromolecule transmembrane transporter activity 3/1051 32/18639 0.09375 1.66261298763083 0.268867800119529 0.805611866919365 GO:0031369 translation initiation factor binding 3/1051 32/18639 0.09375 1.66261298763083 0.268867800119529 0.805611866919365 GO:0043425 bHLH transcription factor binding 3/1051 32/18639 0.09375 1.66261298763083 0.268867800119529 0.805611866919365 GO:0071813 lipoprotein particle binding 3/1051 32/18639 0.09375 1.66261298763083 0.268867800119529 0.805611866919365 GO:0071814 protein-lipid complex binding 3/1051 32/18639 0.09375 1.66261298763083 0.268867800119529 0.805611866919365 GO:0120015 sterol transfer activity 3/1051 32/18639 0.09375 1.66261298763083 0.268867800119529 0.805611866919365 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/1051 18/18639 0.111111111111111 1.97050428163654 0.269800399457473 0.805611866919365 GO:0004970 glutamate-gated receptor activity 2/1051 18/18639 0.111111111111111 1.97050428163654 0.269800399457473 0.805611866919365 GO:0008308 voltage-gated monoatomic anion channel activity 2/1051 18/18639 0.111111111111111 1.97050428163654 0.269800399457473 0.805611866919365 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 2/1051 18/18639 0.111111111111111 1.97050428163654 0.269800399457473 0.805611866919365 GO:0017128 phospholipid scramblase activity 2/1051 18/18639 0.111111111111111 1.97050428163654 0.269800399457473 0.805611866919365 GO:0030228 lipoprotein particle receptor activity 2/1051 18/18639 0.111111111111111 1.97050428163654 0.269800399457473 0.805611866919365 GO:0031690 adrenergic receptor binding 2/1051 18/18639 0.111111111111111 1.97050428163654 0.269800399457473 0.805611866919365 GO:0032393 MHC class I receptor activity 2/1051 18/18639 0.111111111111111 1.97050428163654 0.269800399457473 0.805611866919365 GO:1901611 phosphatidylglycerol binding 2/1051 18/18639 0.111111111111111 1.97050428163654 0.269800399457473 0.805611866919365 GO:0140030 modification-dependent protein binding 12/1051 173/18639 0.069364161849711 1.23014140125287 0.27095467033718 0.806792197670651 GO:0140938 histone H3 methyltransferase activity 4/1051 47/18639 0.0851063829787234 1.50932242848756 0.272517706212131 0.809179669562836 GO:0003713 transcription coactivator activity 17/1051 256/18639 0.06640625 1.17768419957184 0.277556665628279 0.820871715526446 GO:0016410 N-acyltransferase activity 7/1051 94/18639 0.074468085106383 1.32065712492661 0.279413220084123 0.820871715526446 GO:0042562 hormone binding 7/1051 94/18639 0.074468085106383 1.32065712492661 0.279413220084123 0.820871715526446 GO:0005516 calmodulin binding 14/1051 207/18639 0.0676328502415459 1.19943738882224 0.279544271891414 0.820871715526446 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 3/1051 33/18639 0.0909090909090909 1.61223077588444 0.284469043673265 0.830836209746078 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 4/1051 48/18639 0.0833333333333333 1.4778782112274 0.285282423854486 0.830836209746078 GO:0140693 molecular condensate scaffold activity 4/1051 48/18639 0.0833333333333333 1.4778782112274 0.285282423854486 0.830836209746078 GO:0005520 insulin-like growth factor binding 2/1051 19/18639 0.105263157894737 1.86679352997146 0.29114761079695 0.834204609911475 GO:0016918 retinal binding 2/1051 19/18639 0.105263157894737 1.86679352997146 0.29114761079695 0.834204609911475 GO:0030506 ankyrin binding 2/1051 19/18639 0.105263157894737 1.86679352997146 0.29114761079695 0.834204609911475 GO:0046624 sphingolipid transporter activity 2/1051 19/18639 0.105263157894737 1.86679352997146 0.29114761079695 0.834204609911475 GO:0050145 nucleoside monophosphate kinase activity 2/1051 19/18639 0.105263157894737 1.86679352997146 0.29114761079695 0.834204609911475 GO:0070003 threonine-type peptidase activity 2/1051 19/18639 0.105263157894737 1.86679352997146 0.29114761079695 0.834204609911475 GO:0019903 protein phosphatase binding 10/1051 144/18639 0.0694444444444444 1.23156517602284 0.294574025115434 0.841753195423942 GO:0090482 vitamin transmembrane transporter activity 3/1051 34/18639 0.0882352941176471 1.56481222365254 0.300141370901118 0.851521113773054 GO:0030971 receptor tyrosine kinase binding 6/1051 81/18639 0.0740740740740741 1.31366952109102 0.306185045221244 0.851521113773054 GO:0033192 calmodulin-dependent protein phosphatase activity 6/1051 81/18639 0.0740740740740741 1.31366952109102 0.306185045221244 0.851521113773054 GO:0140791 histone H2AXS140 phosphatase activity 6/1051 81/18639 0.0740740740740741 1.31366952109102 0.306185045221244 0.851521113773054 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 6/1051 81/18639 0.0740740740740741 1.31366952109102 0.306185045221244 0.851521113773054 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 6/1051 81/18639 0.0740740740740741 1.31366952109102 0.306185045221244 0.851521113773054 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 6/1051 81/18639 0.0740740740740741 1.31366952109102 0.306185045221244 0.851521113773054 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 6/1051 81/18639 0.0740740740740741 1.31366952109102 0.306185045221244 0.851521113773054 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 6/1051 81/18639 0.0740740740740741 1.31366952109102 0.306185045221244 0.851521113773054 GO:1990439 MAP kinase serine/threonine phosphatase activity 6/1051 81/18639 0.0740740740740741 1.31366952109102 0.306185045221244 0.851521113773054 GO:0048020 CCR chemokine receptor binding 4/1051 50/18639 0.08 1.41876308277831 0.311047334121033 0.851521113773054 GO:0016798 hydrolase activity, acting on glycosyl bonds 9/1051 130/18639 0.0692307692307692 1.227775744712 0.311813245724501 0.851521113773054 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 2/1051 20/18639 0.1 1.77345385347288 0.312411321139691 0.851521113773054 GO:0005326 neurotransmitter transmembrane transporter activity 2/1051 20/18639 0.1 1.77345385347288 0.312411321139691 0.851521113773054 GO:0010851 cyclase regulator activity 2/1051 20/18639 0.1 1.77345385347288 0.312411321139691 0.851521113773054 GO:0016004 phospholipase activator activity 2/1051 20/18639 0.1 1.77345385347288 0.312411321139691 0.851521113773054 GO:0016408 C-acyltransferase activity 2/1051 20/18639 0.1 1.77345385347288 0.312411321139691 0.851521113773054 GO:0030742 GTP-dependent protein binding 2/1051 20/18639 0.1 1.77345385347288 0.312411321139691 0.851521113773054 GO:0008235 metalloexopeptidase activity 5/1051 66/18639 0.0757575757575758 1.34352564657037 0.315182736395675 0.852895894478495 GO:0008170 N-methyltransferase activity 7/1051 98/18639 0.0714285714285714 1.26675275248063 0.315572096713167 0.852895894478495 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 6/1051 82/18639 0.0731707317073171 1.29764916107772 0.316204141364041 0.852895894478495 GO:0033549 MAP kinase phosphatase activity 6/1051 82/18639 0.0731707317073171 1.29764916107772 0.316204141364041 0.852895894478495 GO:0016853 isomerase activity 12/1051 180/18639 0.0666666666666667 1.18230256898192 0.316927449030109 0.852895894478495 GO:0005262 calcium channel activity 9/1051 131/18639 0.0687022900763359 1.2184034107829 0.319708698504039 0.858207945731802 GO:0035401 histone H3Y41 kinase activity 8/1051 115/18639 0.0695652173913043 1.23370702850288 0.322453431722451 0.861226125429561 GO:0140801 histone H2AXY142 kinase activity 8/1051 115/18639 0.0695652173913043 1.23370702850288 0.322453431722451 0.861226125429561 GO:0019209 kinase activator activity 10/1051 148/18639 0.0675675675675676 1.19827963072492 0.324146471907326 0.863208235174198 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 6/1051 83/18639 0.072289156626506 1.28201483383582 0.326272986288678 0.863208235174198 GO:0030165 PDZ domain binding 6/1051 83/18639 0.072289156626506 1.28201483383582 0.326272986288678 0.863208235174198 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 5/1051 67/18639 0.0746268656716418 1.32347302497976 0.326443754035774 0.863208235174198 GO:0005179 hormone activity 9/1051 132/18639 0.0681818181818182 1.20917308191333 0.32764425137874 0.864232851651615 GO:0004033 aldo-keto reductase (NADPH) activity 3/1051 36/18639 0.0833333333333333 1.4778782112274 0.331582618673364 0.864745619363947 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2/1051 21/18639 0.0952380952380952 1.68900366997417 0.333533117534542 0.864745619363947 GO:0005123 death receptor binding 2/1051 21/18639 0.0952380952380952 1.68900366997417 0.333533117534542 0.864745619363947 GO:0009975 cyclase activity 2/1051 21/18639 0.0952380952380952 1.68900366997417 0.333533117534542 0.864745619363947 GO:0035613 RNA stem-loop binding 2/1051 21/18639 0.0952380952380952 1.68900366997417 0.333533117534542 0.864745619363947 GO:0070182 DNA polymerase binding 2/1051 21/18639 0.0952380952380952 1.68900366997417 0.333533117534542 0.864745619363947 GO:0140312 cargo adaptor activity 2/1051 21/18639 0.0952380952380952 1.68900366997417 0.333533117534542 0.864745619363947 GO:0017018 myosin phosphatase activity 6/1051 84/18639 0.0714285714285714 1.26675275248063 0.33638388421405 0.869305576858949 GO:0030159 signaling receptor complex adaptor activity 4/1051 52/18639 0.0769230769230769 1.36419527190222 0.337014792251721 0.869305576858949 GO:0140223 general transcription initiation factor activity 5/1051 68/18639 0.0735294117647059 1.30401018637712 0.33774525234501 0.869305576858949 GO:0031625 ubiquitin protein ligase binding 19/1051 302/18639 0.0629139072847682 1.11574911311208 0.344254081847204 0.883496657071842 GO:0019213 deacetylase activity 3/1051 37/18639 0.0810810810810811 1.43793555686991 0.347297020048045 0.883496657071842 GO:0022829 wide pore channel activity 3/1051 37/18639 0.0810810810810811 1.43793555686991 0.347297020048045 0.883496657071842 GO:0030551 cyclic nucleotide binding 3/1051 37/18639 0.0810810810810811 1.43793555686991 0.347297020048045 0.883496657071842 GO:0004175 endopeptidase activity 25/1051 405/18639 0.0617283950617284 1.09472460090919 0.348690784831048 0.883496657071842 GO:0002039 p53 binding 5/1051 69/18639 0.072463768115942 1.28511148802383 0.34907676008483 0.883496657071842 GO:0016279 protein-lysine N-methyltransferase activity 5/1051 69/18639 0.072463768115942 1.28511148802383 0.34907676008483 0.883496657071842 GO:0016251 RNA polymerase II general transcription initiation factor activity 4/1051 53/18639 0.0754716981132075 1.3384557384701 0.350034520774537 0.883816379057797 GO:0008649 rRNA methyltransferase activity 2/1051 22/18639 0.0909090909090909 1.61223077588444 0.354461427927936 0.886570583264461 GO:0031683 G-protein beta/gamma-subunit complex binding 2/1051 22/18639 0.0909090909090909 1.61223077588444 0.354461427927936 0.886570583264461 GO:0034062 5'-3' RNA polymerase activity 2/1051 22/18639 0.0909090909090909 1.61223077588444 0.354461427927936 0.886570583264461 GO:0097747 RNA polymerase activity 2/1051 22/18639 0.0909090909090909 1.61223077588444 0.354461427927936 0.886570583264461 GO:0030414 peptidase inhibitor activity 11/1051 169/18639 0.0650887573964497 1.15431907622495 0.356252183697019 0.888957913779181 GO:0044389 ubiquitin-like protein ligase binding 20/1051 322/18639 0.062111801242236 1.10152413259185 0.360062739705737 0.893357970850063 GO:0016278 lysine N-methyltransferase activity 5/1051 70/18639 0.0714285714285714 1.26675275248063 0.360428038468202 0.893357970850063 GO:0004722 protein serine/threonine phosphatase activity 7/1051 103/18639 0.0679611650485437 1.20525990041846 0.361803537391236 0.893357970850063 GO:0005501 retinoid binding 3/1051 38/18639 0.0789473684210526 1.40009514747859 0.362973479206127 0.893357970850063 GO:0019840 isoprenoid binding 3/1051 38/18639 0.0789473684210526 1.40009514747859 0.362973479206127 0.893357970850063 GO:0017069 snRNA binding 4/1051 54/18639 0.0740740740740741 1.31366952109102 0.363057990035021 0.893357970850063 GO:0016849 phosphorus-oxygen lyase activity 2/1051 23/18639 0.0869565217391304 1.54213378562859 0.375150936630441 0.905754981696681 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 2/1051 23/18639 0.0869565217391304 1.54213378562859 0.375150936630441 0.905754981696681 GO:0099186 structural constituent of postsynapse 2/1051 23/18639 0.0869565217391304 1.54213378562859 0.375150936630441 0.905754981696681 GO:0140102 catalytic activity, acting on a rRNA 2/1051 23/18639 0.0869565217391304 1.54213378562859 0.375150936630441 0.905754981696681 GO:0000217 DNA secondary structure binding 3/1051 39/18639 0.0769230769230769 1.36419527190222 0.378588556246293 0.905754981696681 GO:0016776 phosphotransferase activity, phosphate group as acceptor 3/1051 39/18639 0.0769230769230769 1.36419527190222 0.378588556246293 0.905754981696681 GO:0042379 chemokine receptor binding 5/1051 72/18639 0.0694444444444444 1.23156517602284 0.383150211712482 0.905754981696681 GO:0030295 protein kinase activator activity 9/1051 139/18639 0.0647482014388489 1.14827947347165 0.384002517642484 0.905754981696681 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 3/1051 40/18639 0.075 1.33009039010466 0.394120316571999 0.905754981696681 GO:0050997 quaternary ammonium group binding 3/1051 40/18639 0.075 1.33009039010466 0.394120316571999 0.905754981696681 GO:0140662 ATP-dependent protein folding chaperone 3/1051 40/18639 0.075 1.33009039010466 0.394120316571999 0.905754981696681 GO:0030215 semaphorin receptor binding 2/1051 24/18639 0.0833333333333333 1.4778782112274 0.395562043854111 0.905754981696681 GO:0030552 cAMP binding 2/1051 24/18639 0.0833333333333333 1.4778782112274 0.395562043854111 0.905754981696681 GO:0060229 lipase activator activity 2/1051 24/18639 0.0833333333333333 1.4778782112274 0.395562043854111 0.905754981696681 GO:0070300 phosphatidic acid binding 2/1051 24/18639 0.0833333333333333 1.4778782112274 0.395562043854111 0.905754981696681 GO:0070840 dynein complex binding 2/1051 24/18639 0.0833333333333333 1.4778782112274 0.395562043854111 0.905754981696681 GO:0001217 DNA-binding transcription repressor activity 17/1051 278/18639 0.0611510791366906 1.08448616938989 0.400622975247607 0.905754981696681 GO:0003684 damaged DNA binding 5/1051 74/18639 0.0675675675675676 1.19827963072492 0.405835095451508 0.905754981696681 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 3/1051 41/18639 0.0731707317073171 1.29764916107772 0.409548306502213 0.905754981696681 GO:0061650 ubiquitin-like protein conjugating enzyme activity 3/1051 41/18639 0.0731707317073171 1.29764916107772 0.409548306502213 0.905754981696681 GO:0001848 complement binding 2/1051 25/18639 0.08 1.41876308277831 0.415660366216358 0.905754981696681 GO:0003707 nuclear steroid receptor activity 2/1051 25/18639 0.08 1.41876308277831 0.415660366216358 0.905754981696681 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 2/1051 25/18639 0.08 1.41876308277831 0.415660366216358 0.905754981696681 GO:0017025 TBP-class protein binding 2/1051 25/18639 0.08 1.41876308277831 0.415660366216358 0.905754981696681 GO:0120020 cholesterol transfer activity 2/1051 25/18639 0.08 1.41876308277831 0.415660366216358 0.905754981696681 GO:0003725 double-stranded RNA binding 5/1051 75/18639 0.0666666666666667 1.18230256898192 0.417140841296183 0.905754981696681 GO:0044183 protein folding chaperone 5/1051 75/18639 0.0666666666666667 1.18230256898192 0.417140841296183 0.905754981696681 GO:0004866 endopeptidase inhibitor activity 10/1051 161/18639 0.062111801242236 1.10152413259185 0.423190364663013 0.905754981696681 GO:0016859 cis-trans isomerase activity 3/1051 42/18639 0.0714285714285714 1.26675275248063 0.424853522880989 0.905754981696681 GO:0019894 kinesin binding 3/1051 42/18639 0.0714285714285714 1.26675275248063 0.424853522880989 0.905754981696681 GO:0031593 polyubiquitin modification-dependent protein binding 4/1051 59/18639 0.0677966101694915 1.20234159557484 0.427744344998048 0.905754981696681 GO:0070063 RNA polymerase binding 4/1051 59/18639 0.0677966101694915 1.20234159557484 0.427744344998048 0.905754981696681 GO:0140104 molecular carrier activity 15/1051 249/18639 0.0602409638554217 1.06834569486318 0.433928256991468 0.905754981696681 GO:0031490 chromatin DNA binding 8/1051 128/18639 0.0625 1.10840865842055 0.434661747305494 0.905754981696681 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 8/1051 128/18639 0.0625 1.10840865842055 0.434661747305494 0.905754981696681 GO:0004529 DNA exonuclease activity 2/1051 26/18639 0.0769230769230769 1.36419527190222 0.435416275315516 0.905754981696681 GO:0005160 transforming growth factor beta receptor binding 2/1051 26/18639 0.0769230769230769 1.36419527190222 0.435416275315516 0.905754981696681 GO:0008066 glutamate receptor activity 2/1051 26/18639 0.0769230769230769 1.36419527190222 0.435416275315516 0.905754981696681 GO:0008157 protein phosphatase 1 binding 2/1051 26/18639 0.0769230769230769 1.36419527190222 0.435416275315516 0.905754981696681 GO:0019865 immunoglobulin binding 2/1051 26/18639 0.0769230769230769 1.36419527190222 0.435416275315516 0.905754981696681 GO:0034237 protein kinase A regulatory subunit binding 2/1051 26/18639 0.0769230769230769 1.36419527190222 0.435416275315516 0.905754981696681 GO:0043548 phosphatidylinositol 3-kinase binding 2/1051 26/18639 0.0769230769230769 1.36419527190222 0.435416275315516 0.905754981696681 GO:0050681 nuclear androgen receptor binding 2/1051 26/18639 0.0769230769230769 1.36419527190222 0.435416275315516 0.905754981696681 GO:0051139 metal cation:proton antiporter activity 2/1051 26/18639 0.0769230769230769 1.36419527190222 0.435416275315516 0.905754981696681 GO:0000182 rDNA binding 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0001094 TFIID-class transcription factor complex binding 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0004090 carbonyl reductase (NADPH) activity 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0005031 tumor necrosis factor receptor activity 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0005381 iron ion transmembrane transporter activity 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0005528 FK506 binding 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0008519 ammonium channel activity 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0015203 polyamine transmembrane transporter activity 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0030957 Tat protein binding 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0031956 medium-chain fatty acid-CoA ligase activity 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0031996 thioesterase binding 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0033204 ribonuclease P RNA binding 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0043121 neurotrophin binding 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0043422 protein kinase B binding 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0045322 unmethylated CpG binding 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0051864 histone H3K36 demethylase activity 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0097177 mitochondrial ribosome binding 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0140135 mechanosensitive monoatomic cation channel activity 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0141109 transporter activator activity 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:1990763 arrestin family protein binding 1/1051 10/18639 0.1 1.77345385347288 0.440402444702528 0.905754981696681 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 4/1051 60/18639 0.0666666666666667 1.18230256898192 0.440506271313287 0.905754981696681 GO:0008276 protein methyltransferase activity 6/1051 95/18639 0.0631578947368421 1.12007611798287 0.448298264002122 0.905754981696681 GO:0015085 calcium ion transmembrane transporter activity 9/1051 147/18639 0.0612244897959184 1.08578807355483 0.44898663846133 0.905754981696681 GO:0008266 poly(U) RNA binding 2/1051 27/18639 0.0740740740740741 1.31366952109102 0.454804471679042 0.905754981696681 GO:0008320 protein transmembrane transporter activity 2/1051 27/18639 0.0740740740740741 1.31366952109102 0.454804471679042 0.905754981696681 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 2/1051 27/18639 0.0740740740740741 1.31366952109102 0.454804471679042 0.905754981696681 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:0001851 complement component C3b binding 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:0005225 volume-sensitive anion channel activity 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:0008172 S-methyltransferase activity 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:0008199 ferric iron binding 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:0008432 JUN kinase binding 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:0008503 benzodiazepine receptor activity 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:0008526 phosphatidylinositol transfer activity 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:0015217 ADP transmembrane transporter activity 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:0032794 GTPase activating protein binding 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:0034056 estrogen response element binding 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:0035252 UDP-xylosyltransferase activity 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:0042285 xylosyltransferase activity 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:0042608 T cell receptor binding 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:0045294 alpha-catenin binding 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:0047676 arachidonate-CoA ligase activity 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:0048185 activin binding 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:0070697 activin receptor binding 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:0070990 snRNP binding 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:0180030 inositol phosphate kinase activity 1/1051 11/18639 0.0909090909090909 1.61223077588444 0.471973491490742 0.905754981696681 GO:1901981 phosphatidylinositol phosphate binding 11/1051 185/18639 0.0594594594594595 1.05448607503793 0.472577122931987 0.905754981696681 GO:0045499 chemorepellent activity 2/1051 28/18639 0.0714285714285714 1.26675275248063 0.473803591568155 0.905754981696681 GO:0046875 ephrin receptor binding 2/1051 28/18639 0.0714285714285714 1.26675275248063 0.473803591568155 0.905754981696681 GO:0051393 alpha-actinin binding 2/1051 28/18639 0.0714285714285714 1.26675275248063 0.473803591568155 0.905754981696681 GO:0051537 2 iron, 2 sulfur cluster binding 2/1051 28/18639 0.0714285714285714 1.26675275248063 0.473803591568155 0.905754981696681 GO:0051959 dynein light intermediate chain binding 2/1051 28/18639 0.0714285714285714 1.26675275248063 0.473803591568155 0.905754981696681 GO:0016247 channel regulator activity 10/1051 168/18639 0.0595238095238095 1.05562729373386 0.476696988345484 0.905754981696681 GO:0005507 copper ion binding 4/1051 63/18639 0.0634920634920635 1.12600244664945 0.47823921227734 0.905754981696681 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 3/1051 46/18639 0.0652173913043478 1.15660033922145 0.484515264639392 0.905754981696681 GO:0030291 protein serine/threonine kinase inhibitor activity 3/1051 46/18639 0.0652173913043478 1.15660033922145 0.484515264639392 0.905754981696681 GO:0051087 protein-folding chaperone binding 8/1051 134/18639 0.0597014925373134 1.05877841998381 0.486149781345849 0.905754981696681 GO:0004536 DNA nuclease activity 4/1051 64/18639 0.0625 1.10840865842055 0.490600154542111 0.905754981696681 GO:0019208 phosphatase regulator activity 7/1051 117/18639 0.0598290598290598 1.06104076703506 0.49171640769071 0.905754981696681 GO:0141108 transporter regulator activity 10/1051 170/18639 0.0588235294117647 1.0432081491017 0.491822416526531 0.905754981696681 GO:0004181 metallocarboxypeptidase activity 2/1051 29/18639 0.0689655172413793 1.22307162308475 0.49239584429363 0.905754981696681 GO:0004629 phospholipase C activity 2/1051 29/18639 0.0689655172413793 1.22307162308475 0.49239584429363 0.905754981696681 GO:0043236 laminin binding 2/1051 29/18639 0.0689655172413793 1.22307162308475 0.49239584429363 0.905754981696681 GO:0061733 protein-lysine-acetyltransferase activity 3/1051 47/18639 0.0638297872340425 1.13199182136567 0.498969643623068 0.905754981696681 GO:0000340 RNA 7-methylguanosine cap binding 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0003720 telomerase activity 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0004032 aldose reductase (NADPH) activity 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0004526 ribonuclease P activity 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0004875 complement receptor activity 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0005025 transforming growth factor beta receptor activity, type I 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0005026 transforming growth factor beta receptor activity, type II 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0005095 GTPase inhibitor activity 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0005165 neurotrophin receptor binding 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0005527 macrolide binding 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0008504 monoamine transmembrane transporter activity 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0008603 cAMP-dependent protein kinase regulator activity 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0010853 cyclase activator activity 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0015132 prostaglandin transmembrane transporter activity 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0015368 calcium:monoatomic cation antiporter activity 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0016273 arginine N-methyltransferase activity 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0016274 protein-arginine N-methyltransferase activity 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0016361 activin receptor activity, type I 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0016362 activin receptor activity, type II 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0016801 hydrolase activity, acting on ether bonds 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0016803 ether hydrolase activity 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0016840 carbon-nitrogen lyase activity 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0017002 activin receptor activity 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0017166 vinculin binding 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0035197 siRNA binding 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0035259 nuclear glucocorticoid receptor binding 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/1051 12/18639 0.0833333333333333 1.4778782112274 0.501764980670645 0.905754981696681 GO:0120013 lipid transfer activity 4/1051 65/18639 0.0615384615384615 1.09135621752177 0.502838008298554 0.905754981696681 GO:0022804 active transmembrane transporter activity 26/1051 457/18639 0.0568927789934354 1.00896718140689 0.51046326176195 0.905754981696681 GO:0001965 G-protein alpha-subunit binding 2/1051 30/18639 0.0666666666666667 1.18230256898192 0.510566677857094 0.905754981696681 GO:0008187 poly-pyrimidine tract binding 2/1051 30/18639 0.0666666666666667 1.18230256898192 0.510566677857094 0.905754981696681 GO:0015215 nucleotide transmembrane transporter activity 2/1051 30/18639 0.0666666666666667 1.18230256898192 0.510566677857094 0.905754981696681 GO:0098918 structural constituent of synapse 2/1051 30/18639 0.0666666666666667 1.18230256898192 0.510566677857094 0.905754981696681 GO:0032182 ubiquitin-like protein binding 7/1051 120/18639 0.0583333333333333 1.03451474785918 0.518727117455092 0.905754981696681 GO:0003712 transcription coregulator activity 28/1051 495/18639 0.0565656565656566 1.00316581610587 0.521380639314539 0.905754981696681 GO:0005253 monoatomic anion channel activity 6/1051 103/18639 0.058252427184466 1.0330799146444 0.527229628478467 0.905754981696681 GO:0001222 transcription corepressor binding 3/1051 49/18639 0.0612244897959184 1.08578807355483 0.527242684712159 0.905754981696681 GO:0060590 ATPase regulator activity 3/1051 49/18639 0.0612244897959184 1.08578807355483 0.527242684712159 0.905754981696681 GO:0005164 tumor necrosis factor receptor binding 2/1051 31/18639 0.0645161290322581 1.14416377643412 0.528304470881294 0.905754981696681 GO:0005184 neuropeptide hormone activity 2/1051 31/18639 0.0645161290322581 1.14416377643412 0.528304470881294 0.905754981696681 GO:0047499 calcium-independent phospholipase A2 activity 2/1051 31/18639 0.0645161290322581 1.14416377643412 0.528304470881294 0.905754981696681 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/1051 13/18639 0.0769230769230769 1.36419527190222 0.529877129986968 0.905754981696681 GO:0003964 RNA-directed DNA polymerase activity 1/1051 13/18639 0.0769230769230769 1.36419527190222 0.529877129986968 0.905754981696681 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/1051 13/18639 0.0769230769230769 1.36419527190222 0.529877129986968 0.905754981696681 GO:0005035 death receptor activity 1/1051 13/18639 0.0769230769230769 1.36419527190222 0.529877129986968 0.905754981696681 GO:0005172 vascular endothelial growth factor receptor binding 1/1051 13/18639 0.0769230769230769 1.36419527190222 0.529877129986968 0.905754981696681 GO:0005338 nucleotide-sugar transmembrane transporter activity 1/1051 13/18639 0.0769230769230769 1.36419527190222 0.529877129986968 0.905754981696681 GO:0005542 folic acid binding 1/1051 13/18639 0.0769230769230769 1.36419527190222 0.529877129986968 0.905754981696681 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/1051 13/18639 0.0769230769230769 1.36419527190222 0.529877129986968 0.905754981696681 GO:0017154 semaphorin receptor activity 1/1051 13/18639 0.0769230769230769 1.36419527190222 0.529877129986968 0.905754981696681 GO:0019855 calcium channel inhibitor activity 1/1051 13/18639 0.0769230769230769 1.36419527190222 0.529877129986968 0.905754981696681 GO:0031432 titin binding 1/1051 13/18639 0.0769230769230769 1.36419527190222 0.529877129986968 0.905754981696681 GO:0031994 insulin-like growth factor I binding 1/1051 13/18639 0.0769230769230769 1.36419527190222 0.529877129986968 0.905754981696681 GO:0032396 inhibitory MHC class I receptor activity 1/1051 13/18639 0.0769230769230769 1.36419527190222 0.529877129986968 0.905754981696681 GO:0035673 oligopeptide transmembrane transporter activity 1/1051 13/18639 0.0769230769230769 1.36419527190222 0.529877129986968 0.905754981696681 GO:0039706 co-receptor binding 1/1051 13/18639 0.0769230769230769 1.36419527190222 0.529877129986968 0.905754981696681 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/1051 13/18639 0.0769230769230769 1.36419527190222 0.529877129986968 0.905754981696681 GO:0046974 histone H3K9 methyltransferase activity 1/1051 13/18639 0.0769230769230769 1.36419527190222 0.529877129986968 0.905754981696681 GO:0046975 histone H3K36 methyltransferase activity 1/1051 13/18639 0.0769230769230769 1.36419527190222 0.529877129986968 0.905754981696681 GO:0051011 microtubule minus-end binding 1/1051 13/18639 0.0769230769230769 1.36419527190222 0.529877129986968 0.905754981696681 GO:0070123 transforming growth factor beta receptor activity, type III 1/1051 13/18639 0.0769230769230769 1.36419527190222 0.529877129986968 0.905754981696681 GO:0071714 icosanoid transmembrane transporter activity 1/1051 13/18639 0.0769230769230769 1.36419527190222 0.529877129986968 0.905754981696681 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 7/1051 122/18639 0.0573770491803279 1.01755548969756 0.536440289546452 0.905754981696681 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 5/1051 86/18639 0.0581395348837209 1.03107782178656 0.53747644895974 0.905754981696681 GO:0030145 manganese ion binding 4/1051 68/18639 0.0588235294117647 1.0432081491017 0.538736112169456 0.905754981696681 GO:0032813 tumor necrosis factor receptor superfamily binding 3/1051 50/18639 0.06 1.06407231208373 0.54104238794138 0.905754981696681 GO:0042277 peptide binding 14/1051 249/18639 0.0562248995983936 0.99712264853897 0.543753801893502 0.905754981696681 GO:0042910 xenobiotic transmembrane transporter activity 2/1051 32/18639 0.0625 1.10840865842055 0.545600248932078 0.905754981696681 GO:0047498 calcium-dependent phospholipase A2 activity 2/1051 32/18639 0.0625 1.10840865842055 0.545600248932078 0.905754981696681 GO:0051059 NF-kappaB binding 2/1051 32/18639 0.0625 1.10840865842055 0.545600248932078 0.905754981696681 GO:0070717 poly-purine tract binding 2/1051 32/18639 0.0625 1.10840865842055 0.545600248932078 0.905754981696681 GO:0140142 nucleocytoplasmic carrier activity 2/1051 32/18639 0.0625 1.10840865842055 0.545600248932078 0.905754981696681 GO:0160041 neuropeptide activity 2/1051 32/18639 0.0625 1.10840865842055 0.545600248932078 0.905754981696681 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 15/1051 268/18639 0.0559701492537313 0.992604768734823 0.549846009142302 0.905754981696681 GO:0008080 N-acetyltransferase activity 4/1051 69/18639 0.0579710144927536 1.02808919041906 0.550407456913126 0.905754981696681 GO:0005216 monoatomic ion channel activity 25/1051 448/18639 0.0558035714285714 0.989650587875493 0.551358457788214 0.905754981696681 GO:0099106 ion channel regulator activity 9/1051 160/18639 0.05625 0.997567792578497 0.551711818248967 0.905754981696681 GO:0005272 sodium channel activity 3/1051 51/18639 0.0588235294117647 1.0432081491017 0.554606670712987 0.905754981696681 GO:0030544 Hsp70 protein binding 3/1051 51/18639 0.0588235294117647 1.0432081491017 0.554606670712987 0.905754981696681 GO:0000149 SNARE binding 6/1051 106/18639 0.0566037735849057 1.00384180385258 0.555647141816511 0.905754981696681 GO:0005347 ATP transmembrane transporter activity 1/1051 14/18639 0.0714285714285714 1.26675275248063 0.5564045183894 0.905754981696681 GO:0008191 metalloendopeptidase inhibitor activity 1/1051 14/18639 0.0714285714285714 1.26675275248063 0.5564045183894 0.905754981696681 GO:0008195 phosphatidate phosphatase activity 1/1051 14/18639 0.0714285714285714 1.26675275248063 0.5564045183894 0.905754981696681 GO:0008494 translation activator activity 1/1051 14/18639 0.0714285714285714 1.26675275248063 0.5564045183894 0.905754981696681 GO:0008559 ABC-type xenobiotic transporter activity 1/1051 14/18639 0.0714285714285714 1.26675275248063 0.5564045183894 0.905754981696681 GO:0015386 potassium:proton antiporter activity 1/1051 14/18639 0.0714285714285714 1.26675275248063 0.5564045183894 0.905754981696681 GO:0019992 diacylglycerol binding 1/1051 14/18639 0.0714285714285714 1.26675275248063 0.5564045183894 0.905754981696681 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/1051 14/18639 0.0714285714285714 1.26675275248063 0.5564045183894 0.905754981696681 GO:0061665 SUMO ligase activity 1/1051 14/18639 0.0714285714285714 1.26675275248063 0.5564045183894 0.905754981696681 GO:0070742 C2H2 zinc finger domain binding 1/1051 14/18639 0.0714285714285714 1.26675275248063 0.5564045183894 0.905754981696681 GO:0071933 Arp2/3 complex binding 1/1051 14/18639 0.0714285714285714 1.26675275248063 0.5564045183894 0.905754981696681 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/1051 14/18639 0.0714285714285714 1.26675275248063 0.5564045183894 0.905754981696681 GO:0098821 BMP receptor activity 1/1051 14/18639 0.0714285714285714 1.26675275248063 0.5564045183894 0.905754981696681 GO:0098847 sequence-specific single stranded DNA binding 1/1051 14/18639 0.0714285714285714 1.26675275248063 0.5564045183894 0.905754981696681 GO:1901612 cardiolipin binding 1/1051 14/18639 0.0714285714285714 1.26675275248063 0.5564045183894 0.905754981696681 GO:0019956 chemokine binding 2/1051 33/18639 0.0606060606060606 1.07482051725629 0.562447423464905 0.909027093874234 GO:0030296 protein tyrosine kinase activator activity 2/1051 33/18639 0.0606060606060606 1.07482051725629 0.562447423464905 0.909027093874234 GO:0071889 14-3-3 protein binding 2/1051 33/18639 0.0606060606060606 1.07482051725629 0.562447423464905 0.909027093874234 GO:0140311 protein sequestering activity 2/1051 33/18639 0.0606060606060606 1.07482051725629 0.562447423464905 0.909027093874234 GO:0005125 cytokine activity 13/1051 234/18639 0.0555555555555556 0.985252140818268 0.562690336565612 0.909027093874234 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 3/1051 52/18639 0.0576923076923077 1.02314645392666 0.567928622455514 0.91536534136625 GO:0003727 single-stranded RNA binding 5/1051 89/18639 0.0561797752808989 0.996322389591507 0.568335959832291 0.91536534136625 GO:0051427 hormone receptor binding 2/1051 34/18639 0.0588235294117647 1.0432081491017 0.578841551750142 0.918375774749094 GO:0005246 calcium channel regulator activity 3/1051 53/18639 0.0566037735849057 1.00384180385258 0.581002268556373 0.918375774749094 GO:0034212 protein N-acetyltransferase activity 3/1051 53/18639 0.0566037735849057 1.00384180385258 0.581002268556373 0.918375774749094 GO:0004089 carbonate dehydratase activity 1/1051 15/18639 0.0666666666666667 1.18230256898192 0.581436403016124 0.918375774749094 GO:0004467 long-chain fatty acid-CoA ligase activity 1/1051 15/18639 0.0666666666666667 1.18230256898192 0.581436403016124 0.918375774749094 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/1051 15/18639 0.0666666666666667 1.18230256898192 0.581436403016124 0.918375774749094 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/1051 15/18639 0.0666666666666667 1.18230256898192 0.581436403016124 0.918375774749094 GO:0015929 hexosaminidase activity 1/1051 15/18639 0.0666666666666667 1.18230256898192 0.581436403016124 0.918375774749094 GO:0017081 chloride channel regulator activity 1/1051 15/18639 0.0666666666666667 1.18230256898192 0.581436403016124 0.918375774749094 GO:0030553 cGMP binding 1/1051 15/18639 0.0666666666666667 1.18230256898192 0.581436403016124 0.918375774749094 GO:0031005 filamin binding 1/1051 15/18639 0.0666666666666667 1.18230256898192 0.581436403016124 0.918375774749094 GO:0034483 heparan sulfate sulfotransferase activity 1/1051 15/18639 0.0666666666666667 1.18230256898192 0.581436403016124 0.918375774749094 GO:0120283 protein serine/threonine kinase binding 1/1051 15/18639 0.0666666666666667 1.18230256898192 0.581436403016124 0.918375774749094 GO:0051287 NAD binding 3/1051 54/18639 0.0555555555555556 0.985252140818268 0.5938225202341 0.927313565121852 GO:0140463 chromatin-protein adaptor activity 3/1051 54/18639 0.0555555555555556 0.985252140818268 0.5938225202341 0.927313565121852 GO:0004623 phospholipase A2 activity 2/1051 35/18639 0.0571428571428571 1.0134022019845 0.594780116244813 0.927313565121852 GO:0016229 steroid dehydrogenase activity 2/1051 35/18639 0.0571428571428571 1.0134022019845 0.594780116244813 0.927313565121852 GO:0061631 ubiquitin conjugating enzyme activity 2/1051 35/18639 0.0571428571428571 1.0134022019845 0.594780116244813 0.927313565121852 GO:1902936 phosphatidylinositol bisphosphate binding 6/1051 111/18639 0.0540540540540541 0.958623704579937 0.601153118567758 0.927313565121852 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 9/1051 167/18639 0.0538922155688623 0.955753573727901 0.603784091138979 0.927313565121852 GO:0000062 fatty-acyl-CoA binding 1/1051 16/18639 0.0625 1.10840865842055 0.605057018374268 0.927313565121852 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 1/1051 16/18639 0.0625 1.10840865842055 0.605057018374268 0.927313565121852 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/1051 16/18639 0.0625 1.10840865842055 0.605057018374268 0.927313565121852 GO:0004708 MAP kinase kinase activity 1/1051 16/18639 0.0625 1.10840865842055 0.605057018374268 0.927313565121852 GO:0008296 3'-5'-DNA exonuclease activity 1/1051 16/18639 0.0625 1.10840865842055 0.605057018374268 0.927313565121852 GO:0015385 sodium:proton antiporter activity 1/1051 16/18639 0.0625 1.10840865842055 0.605057018374268 0.927313565121852 GO:0030275 LRR domain binding 1/1051 16/18639 0.0625 1.10840865842055 0.605057018374268 0.927313565121852 GO:0034450 ubiquitin-ubiquitin ligase activity 1/1051 16/18639 0.0625 1.10840865842055 0.605057018374268 0.927313565121852 GO:0043023 ribosomal large subunit binding 1/1051 16/18639 0.0625 1.10840865842055 0.605057018374268 0.927313565121852 GO:0070411 I-SMAD binding 1/1051 16/18639 0.0625 1.10840865842055 0.605057018374268 0.927313565121852 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/1051 16/18639 0.0625 1.10840865842055 0.605057018374268 0.927313565121852 GO:0140313 molecular sequestering activity 3/1051 55/18639 0.0545454545454545 0.967338465530663 0.606385125207407 0.927313565121852 GO:0051213 dioxygenase activity 5/1051 93/18639 0.0537634408602151 0.953469813695098 0.607761746486936 0.927313565121852 GO:0000993 RNA polymerase II complex binding 2/1051 36/18639 0.0555555555555556 0.985252140818268 0.61026232198431 0.927313565121852 GO:0005484 SNAP receptor activity 2/1051 36/18639 0.0555555555555556 0.985252140818268 0.61026232198431 0.927313565121852 GO:0016409 palmitoyltransferase activity 2/1051 36/18639 0.0555555555555556 0.985252140818268 0.61026232198431 0.927313565121852 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 2/1051 36/18639 0.0555555555555556 0.985252140818268 0.61026232198431 0.927313565121852 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 2/1051 36/18639 0.0555555555555556 0.985252140818268 0.61026232198431 0.927313565121852 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 2/1051 36/18639 0.0555555555555556 0.985252140818268 0.61026232198431 0.927313565121852 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 7/1051 132/18639 0.053030303030303 0.940467952599256 0.620536472560012 0.927313565121852 GO:0030280 structural constituent of skin epidermis 2/1051 37/18639 0.0540540540540541 0.958623704579937 0.625288910666382 0.927313565121852 GO:0004549 tRNA-specific ribonuclease activity 1/1051 17/18639 0.0588235294117647 1.0432081491017 0.627345858716245 0.927313565121852 GO:0004550 nucleoside diphosphate kinase activity 1/1051 17/18639 0.0588235294117647 1.0432081491017 0.627345858716245 0.927313565121852 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/1051 17/18639 0.0588235294117647 1.0432081491017 0.627345858716245 0.927313565121852 GO:0005092 GDP-dissociation inhibitor activity 1/1051 17/18639 0.0588235294117647 1.0432081491017 0.627345858716245 0.927313565121852 GO:0008429 phosphatidylethanolamine binding 1/1051 17/18639 0.0588235294117647 1.0432081491017 0.627345858716245 0.927313565121852 GO:0008569 minus-end-directed microtubule motor activity 1/1051 17/18639 0.0588235294117647 1.0432081491017 0.627345858716245 0.927313565121852 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 1/1051 17/18639 0.0588235294117647 1.0432081491017 0.627345858716245 0.927313565121852 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/1051 17/18639 0.0588235294117647 1.0432081491017 0.627345858716245 0.927313565121852 GO:0016018 cyclosporin A binding 1/1051 17/18639 0.0588235294117647 1.0432081491017 0.627345858716245 0.927313565121852 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/1051 17/18639 0.0588235294117647 1.0432081491017 0.627345858716245 0.927313565121852 GO:0030548 acetylcholine receptor regulator activity 1/1051 17/18639 0.0588235294117647 1.0432081491017 0.627345858716245 0.927313565121852 GO:0031489 myosin V binding 1/1051 17/18639 0.0588235294117647 1.0432081491017 0.627345858716245 0.927313565121852 GO:0032977 membrane insertase activity 1/1051 17/18639 0.0588235294117647 1.0432081491017 0.627345858716245 0.927313565121852 GO:0051787 misfolded protein binding 1/1051 17/18639 0.0588235294117647 1.0432081491017 0.627345858716245 0.927313565121852 GO:0070403 NAD+ binding 1/1051 17/18639 0.0588235294117647 1.0432081491017 0.627345858716245 0.927313565121852 GO:1901567 fatty acid derivative binding 1/1051 17/18639 0.0588235294117647 1.0432081491017 0.627345858716245 0.927313565121852 GO:1990226 histone methyltransferase binding 1/1051 17/18639 0.0588235294117647 1.0432081491017 0.627345858716245 0.927313565121852 GO:0017022 myosin binding 4/1051 76/18639 0.0526315789473684 0.933396764985728 0.627436348698904 0.927313565121852 GO:0015932 nucleobase-containing compound transmembrane transporter activity 3/1051 57/18639 0.0526315789473684 0.933396764985728 0.630724279377663 0.927313565121852 GO:0017124 SH3 domain binding 6/1051 115/18639 0.0521739130434783 0.925280271377156 0.635673595484747 0.927313565121852 GO:0003724 RNA helicase activity 4/1051 77/18639 0.051948051948052 0.921274729076822 0.637726769685418 0.927313565121852 GO:0000146 microfilament motor activity 2/1051 38/18639 0.0526315789473684 0.933396764985728 0.639861990191952 0.927313565121852 GO:0042887 amide transmembrane transporter activity 2/1051 38/18639 0.0526315789473684 0.933396764985728 0.639861990191952 0.927313565121852 GO:0043531 ADP binding 2/1051 38/18639 0.0526315789473684 0.933396764985728 0.639861990191952 0.927313565121852 GO:0035091 phosphatidylinositol binding 15/1051 284/18639 0.0528169014084507 0.936683373313142 0.640662100703707 0.927313565121852 GO:0061980 regulatory RNA binding 3/1051 58/18639 0.0517241379310345 0.91730371731356 0.642496076989246 0.927313565121852 GO:0005506 iron ion binding 8/1051 154/18639 0.051948051948052 0.921274729076822 0.64477735806529 0.927313565121852 GO:0005261 monoatomic cation channel activity 18/1051 341/18639 0.0527859237536657 0.936133998900642 0.648291731906702 0.927313565121852 GO:0000400 four-way junction DNA binding 1/1051 18/18639 0.0555555555555556 0.985252140818268 0.648377944554996 0.927313565121852 GO:0000900 mRNA regulatory element binding translation repressor activity 1/1051 18/18639 0.0555555555555556 0.985252140818268 0.648377944554996 0.927313565121852 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/1051 18/18639 0.0555555555555556 0.985252140818268 0.648377944554996 0.927313565121852 GO:0004706 JUN kinase kinase kinase activity 1/1051 18/18639 0.0555555555555556 0.985252140818268 0.648377944554996 0.927313565121852 GO:0008409 5'-3' exonuclease activity 1/1051 18/18639 0.0555555555555556 0.985252140818268 0.648377944554996 0.927313565121852 GO:0008525 phosphatidylcholine transporter activity 1/1051 18/18639 0.0555555555555556 0.985252140818268 0.648377944554996 0.927313565121852 GO:0015280 ligand-gated sodium channel activity 1/1051 18/18639 0.0555555555555556 0.985252140818268 0.648377944554996 0.927313565121852 GO:0016854 racemase and epimerase activity 1/1051 18/18639 0.0555555555555556 0.985252140818268 0.648377944554996 0.927313565121852 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/1051 18/18639 0.0555555555555556 0.985252140818268 0.648377944554996 0.927313565121852 GO:0017075 syntaxin-1 binding 1/1051 18/18639 0.0555555555555556 0.985252140818268 0.648377944554996 0.927313565121852 GO:0022851 GABA-gated chloride ion channel activity 1/1051 18/18639 0.0555555555555556 0.985252140818268 0.648377944554996 0.927313565121852 GO:0035615 clathrin adaptor activity 1/1051 18/18639 0.0555555555555556 0.985252140818268 0.648377944554996 0.927313565121852 GO:0099602 neurotransmitter receptor regulator activity 1/1051 18/18639 0.0555555555555556 0.985252140818268 0.648377944554996 0.927313565121852 GO:1990381 ubiquitin-specific protease binding 1/1051 18/18639 0.0555555555555556 0.985252140818268 0.648377944554996 0.927313565121852 GO:0005085 guanyl-nucleotide exchange factor activity 12/1051 230/18639 0.0521739130434783 0.925280271377156 0.650785549450961 0.927313565121852 GO:0016779 nucleotidyltransferase activity 7/1051 136/18639 0.0514705882352941 0.912807130463984 0.651720925816196 0.927313565121852 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 2/1051 39/18639 0.0512820512820513 0.909463514601478 0.653984878513339 0.927313565121852 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 2/1051 39/18639 0.0512820512820513 0.909463514601478 0.653984878513339 0.927313565121852 GO:0036002 pre-mRNA binding 3/1051 59/18639 0.0508474576271186 0.901756196681127 0.654000634060203 0.927313565121852 GO:0008186 ATP-dependent activity, acting on RNA 4/1051 79/18639 0.0506329113924051 0.897951318214118 0.657745450037266 0.927313565121852 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 3/1051 60/18639 0.05 0.886726926736441 0.665237179467935 0.927313565121852 GO:0004252 serine-type endopeptidase activity 9/1051 176/18639 0.0511363636363636 0.906879811434997 0.666019503793217 0.927313565121852 GO:0000049 tRNA binding 4/1051 80/18639 0.05 0.886726926736441 0.667470479144016 0.927313565121852 GO:0048306 calcium-dependent protein binding 4/1051 80/18639 0.05 0.886726926736441 0.667470479144016 0.927313565121852 GO:0032451 demethylase activity 2/1051 40/18639 0.05 0.886726926736441 0.667661960720778 0.927313565121852 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/1051 40/18639 0.05 0.886726926736441 0.667661960720778 0.927313565121852 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/1051 19/18639 0.0526315789473684 0.933396764985728 0.668224074208221 0.927313565121852 GO:0004890 GABA-A receptor activity 1/1051 19/18639 0.0526315789473684 0.933396764985728 0.668224074208221 0.927313565121852 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/1051 19/18639 0.0526315789473684 0.933396764985728 0.668224074208221 0.927313565121852 GO:0008381 mechanosensitive monoatomic ion channel activity 1/1051 19/18639 0.0526315789473684 0.933396764985728 0.668224074208221 0.927313565121852 GO:0022821 solute:potassium antiporter activity 1/1051 19/18639 0.0526315789473684 0.933396764985728 0.668224074208221 0.927313565121852 GO:0022840 leak channel activity 1/1051 19/18639 0.0526315789473684 0.933396764985728 0.668224074208221 0.927313565121852 GO:0022842 narrow pore channel activity 1/1051 19/18639 0.0526315789473684 0.933396764985728 0.668224074208221 0.927313565121852 GO:0042577 lipid phosphatase activity 1/1051 19/18639 0.0526315789473684 0.933396764985728 0.668224074208221 0.927313565121852 GO:0042800 histone H3K4 methyltransferase activity 1/1051 19/18639 0.0526315789473684 0.933396764985728 0.668224074208221 0.927313565121852 GO:0043395 heparan sulfate proteoglycan binding 1/1051 19/18639 0.0526315789473684 0.933396764985728 0.668224074208221 0.927313565121852 GO:0120227 acyl-CoA binding 1/1051 19/18639 0.0526315789473684 0.933396764985728 0.668224074208221 0.927313565121852 GO:0017080 sodium channel regulator activity 2/1051 41/18639 0.0487804878048781 0.86509944071848 0.680898558373012 0.941216082640457 GO:0140318 protein transporter activity 2/1051 41/18639 0.0487804878048781 0.86509944071848 0.680898558373012 0.941216082640457 GO:0140828 metal cation:monoatomic cation antiporter activity 2/1051 41/18639 0.0487804878048781 0.86509944071848 0.680898558373012 0.941216082640457 GO:0000339 RNA cap binding 1/1051 20/18639 0.05 0.886726926736441 0.686951061211828 0.942230939442804 GO:0001614 purinergic nucleotide receptor activity 1/1051 20/18639 0.05 0.886726926736441 0.686951061211828 0.942230939442804 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/1051 20/18639 0.05 0.886726926736441 0.686951061211828 0.942230939442804 GO:0015095 magnesium ion transmembrane transporter activity 1/1051 20/18639 0.05 0.886726926736441 0.686951061211828 0.942230939442804 GO:0016502 nucleotide receptor activity 1/1051 20/18639 0.05 0.886726926736441 0.686951061211828 0.942230939442804 GO:0031418 L-ascorbic acid binding 1/1051 20/18639 0.05 0.886726926736441 0.686951061211828 0.942230939442804 GO:0004402 histone acetyltransferase activity 2/1051 42/18639 0.0476190476190476 0.844501834987087 0.693700810147613 0.946603287788078 GO:0004520 DNA endonuclease activity 2/1051 42/18639 0.0476190476190476 0.844501834987087 0.693700810147613 0.946603287788078 GO:0035198 miRNA binding 2/1051 42/18639 0.0476190476190476 0.844501834987087 0.693700810147613 0.946603287788078 GO:0043175 RNA polymerase core enzyme binding 2/1051 42/18639 0.0476190476190476 0.844501834987087 0.693700810147613 0.946603287788078 GO:0022824 transmitter-gated monoatomic ion channel activity 3/1051 63/18639 0.0476190476190476 0.844501834987087 0.697339272878845 0.94913143030757 GO:0022835 transmitter-gated channel activity 3/1051 63/18639 0.0476190476190476 0.844501834987087 0.697339272878845 0.94913143030757 GO:0004527 exonuclease activity 4/1051 84/18639 0.0476190476190476 0.844501834987087 0.704453317796925 0.950524291592158 GO:0001846 opsonin binding 1/1051 21/18639 0.0476190476190476 0.844501834987087 0.704621958395692 0.950524291592158 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/1051 21/18639 0.0476190476190476 0.844501834987087 0.704621958395692 0.950524291592158 GO:0015125 bile acid transmembrane transporter activity 1/1051 21/18639 0.0476190476190476 0.844501834987087 0.704621958395692 0.950524291592158 GO:0036122 BMP binding 1/1051 21/18639 0.0476190476190476 0.844501834987087 0.704621958395692 0.950524291592158 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/1051 21/18639 0.0476190476190476 0.844501834987087 0.704621958395692 0.950524291592158 GO:0061891 calcium ion sensor activity 1/1051 21/18639 0.0476190476190476 0.844501834987087 0.704621958395692 0.950524291592158 GO:0004712 protein serine/threonine/tyrosine kinase activity 2/1051 43/18639 0.0465116279069767 0.824862257429248 0.706075562951841 0.951277976448424 GO:0140097 catalytic activity, acting on DNA 17/1051 336/18639 0.0505952380952381 0.89728319967378 0.712563339128366 0.958803581637282 GO:0160215 deacylase activity 3/1051 65/18639 0.0461538461538462 0.818517163141331 0.717410097705353 0.959621945357546 GO:0019205 nucleobase-containing compound kinase activity 2/1051 44/18639 0.0454545454545455 0.80611538794222 0.718030272695615 0.959621945357546 GO:0008168 methyltransferase activity 10/1051 204/18639 0.0490196078431373 0.869340124251413 0.719991357001032 0.959621945357546 GO:0005243 gap junction channel activity 1/1051 22/18639 0.0454545454545455 0.80611538794222 0.721296269370347 0.959621945357546 GO:0008970 phospholipase A1 activity 1/1051 22/18639 0.0454545454545455 0.80611538794222 0.721296269370347 0.959621945357546 GO:0015377 chloride:monoatomic cation symporter activity 1/1051 22/18639 0.0454545454545455 0.80611538794222 0.721296269370347 0.959621945357546 GO:0033691 sialic acid binding 1/1051 22/18639 0.0454545454545455 0.80611538794222 0.721296269370347 0.959621945357546 GO:0050321 tau-protein kinase activity 1/1051 22/18639 0.0454545454545455 0.80611538794222 0.721296269370347 0.959621945357546 GO:0140784 metal ion sensor activity 1/1051 22/18639 0.0454545454545455 0.80611538794222 0.721296269370347 0.959621945357546 GO:0019888 protein phosphatase regulator activity 5/1051 107/18639 0.0467289719626168 0.828716753959291 0.727968032058247 0.967002503199328 GO:0051539 4 iron, 4 sulfur cluster binding 2/1051 45/18639 0.0444444444444444 0.788201712654615 0.729572913984817 0.967002503199328 GO:0140303 intramembrane lipid transporter activity 2/1051 45/18639 0.0444444444444444 0.788201712654615 0.729572913984817 0.967002503199328 GO:0000295 adenine nucleotide transmembrane transporter activity 1/1051 23/18639 0.0434782608695652 0.771066892814297 0.737030148131252 0.970834011726792 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/1051 23/18639 0.0434782608695652 0.771066892814297 0.737030148131252 0.970834011726792 GO:0005283 amino acid:sodium symporter activity 1/1051 23/18639 0.0434782608695652 0.771066892814297 0.737030148131252 0.970834011726792 GO:0008171 O-methyltransferase activity 1/1051 23/18639 0.0434782608695652 0.771066892814297 0.737030148131252 0.970834011726792 GO:0016917 GABA receptor activity 1/1051 23/18639 0.0434782608695652 0.771066892814297 0.737030148131252 0.970834011726792 GO:0046943 carboxylic acid transmembrane transporter activity 9/1051 188/18639 0.0478723404255319 0.848993866024252 0.739367222846866 0.971135859607352 GO:0004180 carboxypeptidase activity 2/1051 46/18639 0.0434782608695652 0.771066892814297 0.740711898045973 0.971135859607352 GO:0008509 monoatomic anion transmembrane transporter activity 7/1051 149/18639 0.0469798657718121 0.833166239886589 0.741886482193372 0.971135859607352 GO:0004620 phospholipase activity 5/1051 109/18639 0.0458715596330275 0.813510941960038 0.742751845972282 0.971135859607352 GO:0005342 organic acid transmembrane transporter activity 9/1051 189/18639 0.0476190476190476 0.844501834987087 0.744951627919102 0.971135859607352 GO:0005548 phospholipid transporter activity 3/1051 68/18639 0.0441176470588235 0.782406111826272 0.745557241210184 0.971135859607352 GO:0019842 vitamin binding 7/1051 150/18639 0.0466666666666667 0.827611798287345 0.748085133930593 0.971135859607352 GO:0005504 fatty acid binding 2/1051 47/18639 0.0425531914893617 0.75466121424378 0.751455998242546 0.971135859607352 GO:0061749 forked DNA-dependent helicase activity 2/1051 47/18639 0.0425531914893617 0.75466121424378 0.751455998242546 0.971135859607352 GO:1990518 single-stranded 3'-5' DNA helicase activity 2/1051 47/18639 0.0425531914893617 0.75466121424378 0.751455998242546 0.971135859607352 GO:0005543 phospholipid binding 25/1051 497/18639 0.0503018108651912 0.892079403155374 0.751845024265639 0.971135859607352 GO:0004622 lysophospholipase activity 1/1051 24/18639 0.0416666666666667 0.738939105613701 0.751876587447649 0.971135859607352 GO:0015149 hexose transmembrane transporter activity 1/1051 24/18639 0.0416666666666667 0.738939105613701 0.751876587447649 0.971135859607352 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 1/1051 24/18639 0.0416666666666667 0.738939105613701 0.751876587447649 0.971135859607352 GO:0050699 WW domain binding 1/1051 24/18639 0.0416666666666667 0.738939105613701 0.751876587447649 0.971135859607352 GO:0055056 D-glucose transmembrane transporter activity 1/1051 24/18639 0.0416666666666667 0.738939105613701 0.751876587447649 0.971135859607352 GO:0072341 modified amino acid binding 4/1051 91/18639 0.043956043956044 0.779540155372696 0.761803529097603 0.974338758587483 GO:0009378 four-way junction helicase activity 2/1051 48/18639 0.0416666666666667 0.738939105613701 0.761814282588992 0.974338758587483 GO:0016879 ligase activity, forming carbon-nitrogen bonds 2/1051 48/18639 0.0416666666666667 0.738939105613701 0.761814282588992 0.974338758587483 GO:0032266 phosphatidylinositol-3-phosphate binding 2/1051 48/18639 0.0416666666666667 0.738939105613701 0.761814282588992 0.974338758587483 GO:0036121 double-stranded DNA helicase activity 2/1051 48/18639 0.0416666666666667 0.738939105613701 0.761814282588992 0.974338758587483 GO:0043138 3'-5' DNA helicase activity 2/1051 48/18639 0.0416666666666667 0.738939105613701 0.761814282588992 0.974338758587483 GO:0004709 MAP kinase kinase kinase activity 1/1051 25/18639 0.04 0.709381541389153 0.76588559666562 0.974338758587483 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/1051 25/18639 0.04 0.709381541389153 0.76588559666562 0.974338758587483 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 1/1051 25/18639 0.04 0.709381541389153 0.76588559666562 0.974338758587483 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/1051 25/18639 0.04 0.709381541389153 0.76588559666562 0.974338758587483 GO:0140299 molecular sensor activity 3/1051 71/18639 0.0422535211267606 0.749346698650514 0.771419791162527 0.974338758587483 GO:0008236 serine-type peptidase activity 9/1051 194/18639 0.0463917525773196 0.82273632377608 0.771635665588542 0.974338758587483 GO:0016763 pentosyltransferase activity 2/1051 49/18639 0.0408163265306122 0.723858715703217 0.77179605271141 0.974338758587483 GO:0051219 phosphoprotein binding 4/1051 93/18639 0.043010752688172 0.762775850956079 0.77650223305731 0.974338758587483 GO:0016741 transferase activity, transferring one-carbon groups 10/1051 215/18639 0.0465116279069767 0.824862257429248 0.777401721428806 0.974338758587483 GO:0004386 helicase activity 7/1051 155/18639 0.0451612903225806 0.800914643503883 0.777487792569373 0.974338758587483 GO:0004435 phosphatidylinositol phospholipase C activity 1/1051 26/18639 0.0384615384615385 0.682097635951109 0.779104369519624 0.974338758587483 GO:0005112 Notch binding 1/1051 26/18639 0.0384615384615385 0.682097635951109 0.779104369519624 0.974338758587483 GO:0005227 calcium-activated cation channel activity 1/1051 26/18639 0.0384615384615385 0.682097635951109 0.779104369519624 0.974338758587483 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/1051 26/18639 0.0384615384615385 0.682097635951109 0.779104369519624 0.974338758587483 GO:0008143 poly(A) binding 1/1051 26/18639 0.0384615384615385 0.682097635951109 0.779104369519624 0.974338758587483 GO:0008198 ferrous iron binding 1/1051 26/18639 0.0384615384615385 0.682097635951109 0.779104369519624 0.974338758587483 GO:0015145 monosaccharide transmembrane transporter activity 1/1051 26/18639 0.0384615384615385 0.682097635951109 0.779104369519624 0.974338758587483 GO:0015216 purine nucleotide transmembrane transporter activity 1/1051 26/18639 0.0384615384615385 0.682097635951109 0.779104369519624 0.974338758587483 GO:0030507 spectrin binding 1/1051 26/18639 0.0384615384615385 0.682097635951109 0.779104369519624 0.974338758587483 GO:0097602 cullin family protein binding 1/1051 26/18639 0.0384615384615385 0.682097635951109 0.779104369519624 0.974338758587483 GO:0120014 phospholipid transfer activity 1/1051 26/18639 0.0384615384615385 0.682097635951109 0.779104369519624 0.974338758587483 GO:0015605 organophosphate ester transmembrane transporter activity 2/1051 50/18639 0.04 0.709381541389153 0.781410788743495 0.976074816021545 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 3/1051 73/18639 0.0410958904109589 0.728816652112144 0.787437810908649 0.977068301599061 GO:0005048 signal sequence binding 2/1051 51/18639 0.0392156862745098 0.695472099401131 0.790668099683515 0.977068301599061 GO:0016830 carbon-carbon lyase activity 2/1051 51/18639 0.0392156862745098 0.695472099401131 0.790668099683515 0.977068301599061 GO:0017171 serine hydrolase activity 9/1051 198/18639 0.0454545454545455 0.80611538794222 0.791502088888238 0.977068301599061 GO:0001671 ATPase activator activity 1/1051 27/18639 0.037037037037037 0.656834760545512 0.791577442513493 0.977068301599061 GO:0004364 glutathione transferase activity 1/1051 27/18639 0.037037037037037 0.656834760545512 0.791577442513493 0.977068301599061 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/1051 27/18639 0.037037037037037 0.656834760545512 0.791577442513493 0.977068301599061 GO:0023026 MHC class II protein complex binding 1/1051 27/18639 0.037037037037037 0.656834760545512 0.791577442513493 0.977068301599061 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 1/1051 27/18639 0.037037037037037 0.656834760545512 0.791577442513493 0.977068301599061 GO:0035255 ionotropic glutamate receptor binding 1/1051 27/18639 0.037037037037037 0.656834760545512 0.791577442513493 0.977068301599061 GO:0140658 ATP-dependent chromatin remodeler activity 7/1051 158/18639 0.0443037974683544 0.785707403437353 0.793869053459454 0.977068301599061 GO:0016407 acetyltransferase activity 4/1051 96/18639 0.0416666666666667 0.738939105613701 0.797194834913334 0.977068301599061 GO:0016829 lyase activity 9/1051 200/18639 0.045 0.798054234062797 0.80094653050767 0.977068301599061 GO:0005242 inward rectifier potassium channel activity 1/1051 28/18639 0.0357142857142857 0.633376376240315 0.803346844400357 0.977068301599061 GO:0019789 SUMO transferase activity 1/1051 28/18639 0.0357142857142857 0.633376376240315 0.803346844400357 0.977068301599061 GO:0036408 histone H3K14 acetyltransferase activity 1/1051 28/18639 0.0357142857142857 0.633376376240315 0.803346844400357 0.977068301599061 GO:0046966 nuclear thyroid hormone receptor binding 1/1051 28/18639 0.0357142857142857 0.633376376240315 0.803346844400357 0.977068301599061 GO:0050698 proteoglycan sulfotransferase activity 1/1051 28/18639 0.0357142857142857 0.633376376240315 0.803346844400357 0.977068301599061 GO:0051019 mitogen-activated protein kinase binding 1/1051 28/18639 0.0357142857142857 0.633376376240315 0.803346844400357 0.977068301599061 GO:0051119 sugar transmembrane transporter activity 1/1051 28/18639 0.0357142857142857 0.633376376240315 0.803346844400357 0.977068301599061 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/1051 28/18639 0.0357142857142857 0.633376376240315 0.803346844400357 0.977068301599061 GO:0097718 disordered domain specific binding 1/1051 28/18639 0.0357142857142857 0.633376376240315 0.803346844400357 0.977068301599061 GO:0141052 histone H3 demethylase activity 1/1051 28/18639 0.0357142857142857 0.633376376240315 0.803346844400357 0.977068301599061 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 8/1051 181/18639 0.0441988950276243 0.783847007059838 0.806917326211232 0.980289277442903 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 2/1051 53/18639 0.0377358490566038 0.66922786923505 0.808149263486999 0.980478740893289 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/1051 29/18639 0.0344827586206897 0.611535811542373 0.814452237261311 0.980478740893289 GO:0005416 amino acid:monoatomic cation symporter activity 1/1051 29/18639 0.0344827586206897 0.611535811542373 0.814452237261311 0.980478740893289 GO:0010484 histone H3 acetyltransferase activity 1/1051 29/18639 0.0344827586206897 0.611535811542373 0.814452237261311 0.980478740893289 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 1/1051 29/18639 0.0344827586206897 0.611535811542373 0.814452237261311 0.980478740893289 GO:0051861 glycolipid binding 1/1051 29/18639 0.0344827586206897 0.611535811542373 0.814452237261311 0.980478740893289 GO:0097472 cyclin-dependent protein kinase activity 1/1051 29/18639 0.0344827586206897 0.611535811542373 0.814452237261311 0.980478740893289 GO:0106222 lncRNA binding 1/1051 29/18639 0.0344827586206897 0.611535811542373 0.814452237261311 0.980478740893289 GO:0050661 NADP binding 2/1051 54/18639 0.037037037037037 0.656834760545512 0.816392599765956 0.980874391255926 GO:0003697 single-stranded DNA binding 5/1051 121/18639 0.0413223140495868 0.732832170856563 0.819114572250285 0.980874391255926 GO:0016769 transferase activity, transferring nitrogenous groups 1/1051 30/18639 0.0333333333333333 0.591151284490961 0.82493104965456 0.980874391255926 GO:0022839 monoatomic ion-gated channel activity 1/1051 30/18639 0.0333333333333333 0.591151284490961 0.82493104965456 0.980874391255926 GO:0031624 ubiquitin conjugating enzyme binding 1/1051 30/18639 0.0333333333333333 0.591151284490961 0.82493104965456 0.980874391255926 GO:0032452 histone demethylase activity 1/1051 30/18639 0.0333333333333333 0.591151284490961 0.82493104965456 0.980874391255926 GO:0043995 histone H4K5 acetyltransferase activity 1/1051 30/18639 0.0333333333333333 0.591151284490961 0.82493104965456 0.980874391255926 GO:0043996 histone H4K8 acetyltransferase activity 1/1051 30/18639 0.0333333333333333 0.591151284490961 0.82493104965456 0.980874391255926 GO:0043997 histone H4K12 acetyltransferase activity 1/1051 30/18639 0.0333333333333333 0.591151284490961 0.82493104965456 0.980874391255926 GO:0051721 protein phosphatase 2A binding 1/1051 30/18639 0.0333333333333333 0.591151284490961 0.82493104965456 0.980874391255926 GO:0070566 adenylyltransferase activity 1/1051 30/18639 0.0333333333333333 0.591151284490961 0.82493104965456 0.980874391255926 GO:0015276 ligand-gated monoatomic ion channel activity 8/1051 186/18639 0.043010752688172 0.762775850956079 0.829664397642907 0.982641969191686 GO:0016835 carbon-oxygen lyase activity 3/1051 79/18639 0.0379746835443038 0.673463488660588 0.829974973149175 0.982641969191686 GO:0019212 phosphatase inhibitor activity 2/1051 56/18639 0.0357142857142857 0.633376376240315 0.831933365341136 0.982641969191686 GO:0030170 pyridoxal phosphate binding 2/1051 56/18639 0.0357142857142857 0.633376376240315 0.831933365341136 0.982641969191686 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 2/1051 56/18639 0.0357142857142857 0.633376376240315 0.831933365341136 0.982641969191686 GO:0008327 methyl-CpG binding 1/1051 31/18639 0.032258064516129 0.572081888217059 0.834818602280336 0.982641969191686 GO:0070273 phosphatidylinositol-4-phosphate binding 1/1051 31/18639 0.032258064516129 0.572081888217059 0.834818602280336 0.982641969191686 GO:0072349 modified amino acid transmembrane transporter activity 1/1051 31/18639 0.032258064516129 0.572081888217059 0.834818602280336 0.982641969191686 GO:0140457 protein demethylase activity 1/1051 31/18639 0.032258064516129 0.572081888217059 0.834818602280336 0.982641969191686 GO:0008514 organic anion transmembrane transporter activity 12/1051 269/18639 0.0446096654275093 0.791131830545524 0.835661655831876 0.982641969191686 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 10/1051 229/18639 0.0436681222707424 0.77443399714973 0.837615937461867 0.983400677401947 GO:0022834 ligand-gated channel activity 8/1051 188/18639 0.0425531914893617 0.75466121424378 0.838157115452647 0.983400677401947 GO:0070279 vitamin B6 binding 2/1051 57/18639 0.0350877192982456 0.622264509990485 0.839250059376171 0.983597368375822 GO:0008094 ATP-dependent activity, acting on DNA 9/1051 210/18639 0.0428571428571429 0.760051651488378 0.84341791211233 0.983680451146073 GO:0030515 snoRNA binding 1/1051 32/18639 0.03125 0.554204329210276 0.844148226581893 0.983680451146073 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/1051 32/18639 0.03125 0.554204329210276 0.844148226581893 0.983680451146073 GO:0017116 single-stranded DNA helicase activity 2/1051 58/18639 0.0344827586206897 0.611535811542373 0.846276987318561 0.983680451146073 GO:0140416 transcription regulator inhibitor activity 1/1051 33/18639 0.0303030303030303 0.537410258628146 0.852951376679298 0.983680451146073 GO:0001786 phosphatidylserine binding 2/1051 59/18639 0.0338983050847458 0.601170797787418 0.853023526029381 0.983680451146073 GO:0015459 potassium channel regulator activity 2/1051 59/18639 0.0338983050847458 0.601170797787418 0.853023526029381 0.983680451146073 GO:0005254 chloride channel activity 3/1051 83/18639 0.036144578313253 0.64100741691791 0.85409308409359 0.983680451146073 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/1051 60/18639 0.0333333333333333 0.591151284490961 0.859498917290121 0.983680451146073 GO:0000510 H3-H4 histone complex chaperone activity 6/1051 151/18639 0.0397350993377483 0.704683650386576 0.860083885846835 0.983680451146073 GO:0140584 chromatin extrusion motor activity 6/1051 151/18639 0.0397350993377483 0.704683650386576 0.860083885846835 0.983680451146073 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 6/1051 151/18639 0.0397350993377483 0.704683650386576 0.860083885846835 0.983680451146073 GO:0140849 ATP-dependent H2AZ histone chaperone activity 6/1051 151/18639 0.0397350993377483 0.704683650386576 0.860083885846835 0.983680451146073 GO:0008376 acetylgalactosaminyltransferase activity 1/1051 34/18639 0.0294117647058824 0.521604074550848 0.861257735010485 0.983680451146073 GO:0015020 glucuronosyltransferase activity 1/1051 34/18639 0.0294117647058824 0.521604074550848 0.861257735010485 0.983680451146073 GO:0016831 carboxy-lyase activity 1/1051 34/18639 0.0294117647058824 0.521604074550848 0.861257735010485 0.983680451146073 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/1051 34/18639 0.0294117647058824 0.521604074550848 0.861257735010485 0.983680451146073 GO:0030332 cyclin binding 1/1051 34/18639 0.0294117647058824 0.521604074550848 0.861257735010485 0.983680451146073 GO:0052866 phosphatidylinositol phosphate phosphatase activity 1/1051 34/18639 0.0294117647058824 0.521604074550848 0.861257735010485 0.983680451146073 GO:0016298 lipase activity 5/1051 130/18639 0.0384615384615385 0.682097635951109 0.863500432249818 0.983680451146073 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 5/1051 130/18639 0.0384615384615385 0.682097635951109 0.863500432249818 0.983680451146073 GO:0015616 DNA translocase activity 6/1051 152/18639 0.0394736842105263 0.700047573739296 0.864190197718083 0.983680451146073 GO:0140674 ATP-dependent histone chaperone activity 6/1051 152/18639 0.0394736842105263 0.700047573739296 0.864190197718083 0.983680451146073 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 2/1051 61/18639 0.0327868852459016 0.581460279827175 0.865712253221654 0.983680451146073 GO:0016836 hydro-lyase activity 2/1051 61/18639 0.0327868852459016 0.581460279827175 0.865712253221654 0.983680451146073 GO:0003774 cytoskeletal motor activity 6/1051 153/18639 0.0392156862745098 0.695472099401131 0.86819617078173 0.983680451146073 GO:0061775 cohesin loader activity 6/1051 153/18639 0.0392156862745098 0.695472099401131 0.86819617078173 0.983680451146073 GO:0005154 epidermal growth factor receptor binding 1/1051 35/18639 0.0285714285714286 0.506701100992252 0.869095312033005 0.983680451146073 GO:0005343 organic acid:sodium symporter activity 1/1051 35/18639 0.0285714285714286 0.506701100992252 0.869095312033005 0.983680451146073 GO:0010485 histone H4 acetyltransferase activity 1/1051 35/18639 0.0285714285714286 0.506701100992252 0.869095312033005 0.983680451146073 GO:0043015 gamma-tubulin binding 1/1051 35/18639 0.0285714285714286 0.506701100992252 0.869095312033005 0.983680451146073 GO:0140566 histone reader activity 1/1051 35/18639 0.0285714285714286 0.506701100992252 0.869095312033005 0.983680451146073 GO:0022832 voltage-gated channel activity 7/1051 175/18639 0.04 0.709381541389153 0.869858536290977 0.983680451146073 GO:1901682 sulfur compound transmembrane transporter activity 2/1051 63/18639 0.0317460317460317 0.563001223324725 0.877388306098141 0.99114109392383 GO:0003730 mRNA 3'-UTR binding 11/1051 262/18639 0.0419847328244275 0.744579862145104 0.879004142004406 0.991912317357413 GO:0004197 cysteine-type endopeptidase activity 3/1051 88/18639 0.0340909090909091 0.604586540956665 0.879996222384137 0.991978774543306 GO:0023023 MHC protein complex binding 1/1051 37/18639 0.027027027027027 0.479311852289968 0.883468363366047 0.994837786290369 GO:0099094 ligand-gated monoatomic cation channel activity 5/1051 136/18639 0.0367647058823529 0.65200509318856 0.887703188412573 0.998548665907477 GO:0003689 DNA clamp loader activity 6/1051 160/18639 0.0375 0.665045195052331 0.893562184343077 0.999999995723101 GO:0008173 RNA methyltransferase activity 2/1051 67/18639 0.0298507462686567 0.529389209991905 0.897976631281148 0.999999995723101 GO:0015144 carbohydrate transmembrane transporter activity 1/1051 40/18639 0.025 0.443363463368221 0.902126227134017 0.999999995723101 GO:0061791 GTPase motor activity 1/1051 40/18639 0.025 0.443363463368221 0.902126227134017 0.999999995723101 GO:0071949 FAD binding 1/1051 40/18639 0.025 0.443363463368221 0.902126227134017 0.999999995723101 GO:1990606 membrane scission GTPase motor activity 1/1051 40/18639 0.025 0.443363463368221 0.902126227134017 0.999999995723101 GO:0141003 histone H2AX kinase activity 15/1051 354/18639 0.0423728813559322 0.751463497234272 0.90247639300735 0.999999995723101 GO:0003777 microtubule motor activity 2/1051 68/18639 0.0294117647058824 0.521604074550848 0.902595400677238 0.999999995723101 GO:0140713 histone chaperone activity 6/1051 164/18639 0.0365853658536585 0.64882458053886 0.906097383714254 0.999999995723101 GO:0098960 postsynaptic neurotransmitter receptor activity 2/1051 69/18639 0.0289855072463768 0.514044595209531 0.907018317534739 0.999999995723101 GO:0001530 lipopolysaccharide binding 1/1051 41/18639 0.024390243902439 0.43254972035924 0.907656918853042 0.999999995723101 GO:0004812 aminoacyl-tRNA ligase activity 1/1051 41/18639 0.024390243902439 0.43254972035924 0.907656918853042 0.999999995723101 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/1051 41/18639 0.024390243902439 0.43254972035924 0.907656918853042 0.999999995723101 GO:0016875 ligase activity, forming carbon-oxygen bonds 1/1051 41/18639 0.024390243902439 0.43254972035924 0.907656918853042 0.999999995723101 GO:0042287 MHC protein binding 1/1051 41/18639 0.024390243902439 0.43254972035924 0.907656918853042 0.999999995723101 GO:0004518 nuclease activity 8/1051 209/18639 0.0382775119617225 0.678834010898711 0.908430794655674 0.999999995723101 GO:0140996 histone H3 kinase activity 15/1051 357/18639 0.0420168067226891 0.745148677929783 0.908742918025261 0.999999995723101 GO:0140597 protein carrier chaperone 7/1051 188/18639 0.0372340425531915 0.660328562463307 0.910963976039064 0.999999995723101 GO:0043177 organic acid binding 7/1051 189/18639 0.037037037037037 0.656834760545512 0.913605794540099 0.999999995723101 GO:0008017 microtubule binding 11/1051 276/18639 0.0398550724637681 0.706811318413106 0.91438064294846 0.999999995723101 GO:0035173 histone kinase activity 15/1051 360/18639 0.0416666666666667 0.738939105613701 0.914674158570831 0.999999995723101 GO:0015108 chloride transmembrane transporter activity 4/1051 121/18639 0.0330578512396694 0.586265736685251 0.915473813254977 0.999999995723101 GO:0030594 neurotransmitter receptor activity 3/1051 97/18639 0.0309278350515464 0.548490882517387 0.916481968203401 0.999999995723101 GO:0005245 voltage-gated calcium channel activity 1/1051 43/18639 0.0232558139534884 0.412431128714624 0.917799165232997 0.999999995723101 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/1051 43/18639 0.0232558139534884 0.412431128714624 0.917799165232997 0.999999995723101 GO:0008528 G protein-coupled peptide receptor activity 4/1051 122/18639 0.0327868852459016 0.581460279827175 0.918555546464795 0.999999995723101 GO:0016790 thiolester hydrolase activity 1/1051 44/18639 0.0227272727272727 0.40305769397111 0.922444953431541 0.999999995723101 GO:0043014 alpha-tubulin binding 1/1051 44/18639 0.0227272727272727 0.40305769397111 0.922444953431541 0.999999995723101 GO:0015631 tubulin binding 16/1051 385/18639 0.0415584415584416 0.737019783261458 0.922479838311135 0.999999995723101 GO:0004521 RNA endonuclease activity 2/1051 73/18639 0.0273972602739726 0.485877768074762 0.922895843937648 0.999999995723101 GO:0043130 ubiquitin binding 3/1051 100/18639 0.03 0.532036156041865 0.9261915216449 0.999999995723101 GO:0003678 DNA helicase activity 2/1051 74/18639 0.027027027027027 0.479311852289968 0.926445968963934 0.999999995723101 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/1051 45/18639 0.0222222222222222 0.394100856327307 0.926828408873512 0.999999995723101 GO:0042605 peptide antigen binding 1/1051 45/18639 0.0222222222222222 0.394100856327307 0.926828408873512 0.999999995723101 GO:0046915 transition metal ion transmembrane transporter activity 1/1051 45/18639 0.0222222222222222 0.394100856327307 0.926828408873512 0.999999995723101 GO:0005244 voltage-gated monoatomic ion channel activity 6/1051 173/18639 0.0346820809248555 0.615070700626433 0.929724672174669 0.999999995723101 GO:0030276 clathrin binding 1/1051 46/18639 0.0217391304347826 0.385533446407148 0.930964331336346 0.999999995723101 GO:0015171 amino acid transmembrane transporter activity 3/1051 102/18639 0.0294117647058824 0.521604074550848 0.932077446522272 0.999999995723101 GO:0004519 endonuclease activity 4/1051 127/18639 0.031496062992126 0.558568142826105 0.932503474339066 0.999999995723101 GO:0004674 protein serine/threonine kinase activity 18/1051 433/18639 0.0415704387990762 0.737232548787804 0.932963027223444 0.999999995723101 GO:0001784 phosphotyrosine residue binding 1/1051 47/18639 0.0212765957446809 0.37733060712189 0.934866686403602 0.999999995723101 GO:0099095 ligand-gated monoatomic anion channel activity 1/1051 47/18639 0.0212765957446809 0.37733060712189 0.934866686403602 0.999999995723101 GO:0140359 ABC-type transporter activity 1/1051 47/18639 0.0212765957446809 0.37733060712189 0.934866686403602 0.999999995723101 GO:0001653 peptide receptor activity 4/1051 128/18639 0.03125 0.554204329210276 0.935019287135131 0.999999995723101 GO:0033293 monocarboxylic acid binding 2/1051 79/18639 0.0253164556962025 0.448975659107059 0.941995700696836 0.999999995723101 GO:0035254 glutamate receptor binding 1/1051 49/18639 0.0204081632653061 0.361929357851609 0.942022664936603 0.999999995723101 GO:0042393 histone binding 9/1051 247/18639 0.0364372469635627 0.646197760374735 0.942153448964263 0.999999995723101 GO:0015101 organic cation transmembrane transporter activity 2/1051 81/18639 0.0246913580246914 0.437889840363675 0.947294858837845 0.999999995723101 GO:0106310 protein serine kinase activity 14/1051 361/18639 0.038781163434903 0.687766037357905 0.949524770684682 0.999999995723101 GO:0022836 gated channel activity 12/1051 318/18639 0.0377358490566038 0.66922786923505 0.949749237791284 0.999999995723101 GO:0004864 protein phosphatase inhibitor activity 1/1051 53/18639 0.0188679245283019 0.334613934617525 0.954064166421005 0.999999995723101 GO:0005544 calcium-dependent phospholipid binding 1/1051 53/18639 0.0188679245283019 0.334613934617525 0.954064166421005 0.999999995723101 GO:0008146 sulfotransferase activity 1/1051 53/18639 0.0188679245283019 0.334613934617525 0.954064166421005 0.999999995723101 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/1051 53/18639 0.0188679245283019 0.334613934617525 0.954064166421005 0.999999995723101 GO:0046873 metal ion transmembrane transporter activity 18/1051 450/18639 0.04 0.709381541389153 0.954223337115899 0.999999995723101 GO:0031406 carboxylic acid binding 6/1051 187/18639 0.0320855614973262 0.569022626782743 0.956120461611671 0.999999995723101 GO:0015081 sodium ion transmembrane transporter activity 5/1051 164/18639 0.0304878048780488 0.54068715044905 0.957803461206113 0.999999995723101 GO:0016887 ATP hydrolysis activity 16/1051 417/18639 0.0383693045563549 0.680461910205423 0.963559089859576 0.999999995723101 GO:0008408 3'-5' exonuclease activity 1/1051 58/18639 0.0172413793103448 0.305767905771187 0.965665021400218 0.999999995723101 GO:0045309 protein phosphorylated amino acid binding 1/1051 59/18639 0.0169491525423729 0.300585398893709 0.967607116147991 0.999999995723101 GO:0052689 carboxylic ester hydrolase activity 2/1051 92/18639 0.0217391304347826 0.385533446407148 0.969107954901656 0.999999995723101 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 3/1051 122/18639 0.0245901639344262 0.436095209870381 0.971222661573325 0.999999995723101 GO:0042626 ATPase-coupled transmembrane transporter activity 2/1051 98/18639 0.0204081632653061 0.361929357851609 0.977023269655193 0.999999995723101 GO:0061659 ubiquitin-like protein ligase activity 13/1051 372/18639 0.0349462365591398 0.619755378901814 0.979070080379112 0.999999995723101 GO:0061630 ubiquitin protein ligase activity 12/1051 353/18639 0.0339943342776204 0.602873831208912 0.981157391881595 0.999999995723101 GO:0015079 potassium ion transmembrane transporter activity 4/1051 160/18639 0.025 0.443363463368221 0.981913447700181 0.999999995723101 GO:0008234 cysteine-type peptidase activity 5/1051 187/18639 0.0267379679144385 0.474185522318953 0.98238149175641 0.999999995723101 GO:0016782 transferase activity, transferring sulphur-containing groups 1/1051 70/18639 0.0142857142857143 0.253350550496126 0.982931386355383 0.999999995723101 GO:0015297 antiporter activity 3/1051 135/18639 0.0222222222222222 0.394100856327307 0.983906644157396 0.999999995723101 GO:0016755 aminoacyltransferase activity 18/1051 496/18639 0.0362903225806452 0.643592124244191 0.985253415839673 0.999999995723101 GO:0015103 inorganic anion transmembrane transporter activity 4/1051 165/18639 0.0242424242424242 0.429928206902517 0.985331698707646 0.999999995723101 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 7/1051 243/18639 0.0288065843621399 0.510871480424287 0.985603756835824 0.999999995723101 GO:0004843 cysteine-type deubiquitinase activity 2/1051 108/18639 0.0185185185185185 0.328417380272756 0.986057931419041 0.999999995723101 GO:0140098 catalytic activity, acting on RNA 13/1051 387/18639 0.0335917312661499 0.59573385258779 0.98643443555862 0.999999995723101 GO:0140767 enzyme-substrate adaptor activity 3/1051 139/18639 0.0215827338129496 0.38275982449055 0.986583368963887 0.999999995723101 GO:0004676 3-phosphoinositide-dependent protein kinase activity 7/1051 245/18639 0.0285714285714286 0.506701100992252 0.986601289568072 0.999999995723101 GO:0004711 ribosomal protein S6 kinase activity 7/1051 245/18639 0.0285714285714286 0.506701100992252 0.986601289568072 0.999999995723101 GO:0035175 histone H3S10 kinase activity 7/1051 245/18639 0.0285714285714286 0.506701100992252 0.986601289568072 0.999999995723101 GO:0035979 histone H2AXS139 kinase activity 7/1051 245/18639 0.0285714285714286 0.506701100992252 0.986601289568072 0.999999995723101 GO:0044022 histone H3S28 kinase activity 7/1051 245/18639 0.0285714285714286 0.506701100992252 0.986601289568072 0.999999995723101 GO:0044023 histone H4S1 kinase activity 7/1051 245/18639 0.0285714285714286 0.506701100992252 0.986601289568072 0.999999995723101 GO:0044024 histone H2AS1 kinase activity 7/1051 245/18639 0.0285714285714286 0.506701100992252 0.986601289568072 0.999999995723101 GO:0044025 histone H2BS14 kinase activity 7/1051 245/18639 0.0285714285714286 0.506701100992252 0.986601289568072 0.999999995723101 GO:0072354 histone H3T3 kinase activity 7/1051 245/18639 0.0285714285714286 0.506701100992252 0.986601289568072 0.999999995723101 GO:0072371 histone H2AS121 kinase activity 7/1051 245/18639 0.0285714285714286 0.506701100992252 0.986601289568072 0.999999995723101 GO:0072518 Rho-dependent protein serine/threonine kinase activity 7/1051 245/18639 0.0285714285714286 0.506701100992252 0.986601289568072 0.999999995723101 GO:0140823 histone H2BS36 kinase activity 7/1051 245/18639 0.0285714285714286 0.506701100992252 0.986601289568072 0.999999995723101 GO:0140855 histone H3S57 kinase activity 7/1051 245/18639 0.0285714285714286 0.506701100992252 0.986601289568072 0.999999995723101 GO:0140995 histone H2A kinase activity 7/1051 245/18639 0.0285714285714286 0.506701100992252 0.986601289568072 0.999999995723101 GO:0140997 histone H4 kinase activity 7/1051 245/18639 0.0285714285714286 0.506701100992252 0.986601289568072 0.999999995723101 GO:0140998 histone H2B kinase activity 7/1051 245/18639 0.0285714285714286 0.506701100992252 0.986601289568072 0.999999995723101 GO:1990244 histone H2AT120 kinase activity 7/1051 245/18639 0.0285714285714286 0.506701100992252 0.986601289568072 0.999999995723101 GO:0004677 DNA-dependent protein kinase activity 7/1051 246/18639 0.0284552845528455 0.504641340419113 0.987075473025959 0.999999995723101 GO:0140857 histone H3T45 kinase activity 7/1051 246/18639 0.0284552845528455 0.504641340419113 0.987075473025959 0.999999995723101 GO:0019787 ubiquitin-like protein transferase activity 17/1051 479/18639 0.0354906054279749 0.629409509583278 0.987125090820639 0.999999995723101 GO:0035402 histone H3T11 kinase activity 7/1051 247/18639 0.0283400809716599 0.502598258069238 0.987533923198914 0.999999995723101 GO:0035403 histone H3T6 kinase activity 7/1051 247/18639 0.0283400809716599 0.502598258069238 0.987533923198914 0.999999995723101 GO:0004679 AMP-activated protein kinase activity 7/1051 248/18639 0.0282258064516129 0.500571652189927 0.987977115805501 0.999999995723101 GO:0015370 solute:sodium symporter activity 1/1051 79/18639 0.0126582278481013 0.224487829553529 0.98989789752436 0.999999995723101 GO:0101005 deubiquitinase activity 2/1051 115/18639 0.0173913043478261 0.308426757125719 0.990212328866227 0.999999995723101 GO:0015294 solute:monoatomic cation symporter activity 2/1051 116/18639 0.0172413793103448 0.305767905771187 0.990697047616461 0.999999995723101 GO:0004842 ubiquitin-protein transferase activity 15/1051 449/18639 0.0334075723830735 0.59246787977936 0.991567097067786 0.999999995723101 GO:0004540 RNA nuclease activity 2/1051 121/18639 0.0165289256198347 0.293132868342625 0.992789848914061 0.999999995723101 GO:0050660 flavin adenine dinucleotide binding 1/1051 86/18639 0.0116279069767442 0.206215564357312 0.99328314671506 0.999999995723101 GO:0005267 potassium channel activity 2/1051 124/18639 0.0161290322580645 0.286040944108529 0.993816360735595 0.999999995723101 GO:0019783 ubiquitin-like protein peptidase activity 2/1051 127/18639 0.015748031496063 0.279284071413052 0.994699291842946 0.999999995723101 GO:0005249 voltage-gated potassium channel activity 1/1051 98/18639 0.0102040816326531 0.180964678925804 0.996664542070554 0.999999995723101 GO:0140101 catalytic activity, acting on a tRNA 2/1051 139/18639 0.0143884892086331 0.255173216327034 0.997150633418633 0.999999995723101 GO:0003823 antigen binding 3/1051 174/18639 0.0172413793103448 0.305767905771187 0.997403942116072 0.999999995723101 GO:0022843 voltage-gated monoatomic cation channel activity 2/1051 143/18639 0.013986013986014 0.248035503982221 0.997686617887187 0.999999995723101 GO:0004497 monooxygenase activity 1/1051 106/18639 0.00943396226415094 0.167306967308763 0.997908926542662 0.999999995723101 GO:0008194 UDP-glycosyltransferase activity 2/1051 145/18639 0.0137931034482759 0.244614324616949 0.997916058913024 0.999999995723101 GO:0015293 symporter activity 2/1051 146/18639 0.0136986301369863 0.242938884037381 0.998022222889544 0.999999995723101 GO:0015291 secondary active transmembrane transporter activity 6/1051 287/18639 0.0209059233449477 0.370756903165063 0.999100567943131 0.999999995723101 GO:0045182 translation regulator activity 6/1051 356/18639 0.0168539325842697 0.298896716877452 0.999956978036757 0.999999995723101 GO:0016757 glycosyltransferase activity 3/1051 267/18639 0.0112359550561798 0.199264477918301 0.999975470464863 0.999999995723101 GO:0016758 hexosyltransferase activity 1/1051 197/18639 0.0050761421319797 0.0900230382473545 0.999989830225386 0.999999995723101 GO:0030371 translation repressor activity 1/1051 329/18639 0.00303951367781155 0.0539043724459843 0.999999995723101 0.999999995723101