ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	98/2277	175/18639	0.56	4.58403162055336	3.04488286117052e-44	3.87918076513125e-41
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	44/2277	68/18639	0.647058823529412	5.29667519181586	3.47844429359839e-24	2.21576901502217e-21
GO:0008137	NADH dehydrogenase (ubiquinone) activity	30/2277	41/18639	0.731707317073171	5.98958835438157	2.76238372065578e-19	1.04086198388327e-16
GO:0015078	proton transmembrane transporter activity	70/2277	185/18639	0.378378378378378	3.09731866253605	3.26801250826772e-19	1.04086198388327e-16
GO:0003954	NADH dehydrogenase activity	31/2277	44/18639	0.704545454545455	5.76724757455983	4.27081801066858e-19	1.08820442911836e-16
GO:0009055	electron transfer activity	52/2277	116/18639	0.448275862068966	3.66948344009813	2.21257674970075e-18	4.69803796519793e-16
GO:0022853	active monoatomic ion transmembrane transporter activity	49/2277	118/18639	0.415254237288136	3.39917598981711	9.37203850399548e-16	1.70571100772718e-13
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	32/2277	58/18639	0.551724137931034	4.51628731089001	4.36979517556349e-15	6.95889881708486e-13
GO:0015399	primary active transmembrane transporter activity	55/2277	166/18639	0.331325301204819	2.71215295966475	1.29714332157087e-12	1.83617843520143e-10
GO:0016651	oxidoreductase activity, acting on NAD(P)H	37/2277	88/18639	0.420454545454545	3.44174452030183	1.92782337192731e-12	2.45604697583539e-10
GO:0030695	GTPase regulator activity	103/2277	489/18639	0.210633946830266	1.72420120112838	1.53021066823156e-08	1.77226217393364e-06
GO:0060589	nucleoside-triphosphatase regulator activity	103/2277	490/18639	0.210204081632653	1.7206824231669	1.70983130482579e-08	1.81527090195671e-06
GO:0055105	ubiquitin-protein transferase inhibitor activity	10/2277	15/18639	0.666666666666667	5.45718050065876	1.21722652814828e-06	0.000112322779085803
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	11/2277	18/18639	0.611111111111111	5.0024154589372	1.23431625369014e-06	0.000112322779085803
GO:0016675	oxidoreductase activity, acting on a heme group of donors	10/2277	16/18639	0.625	5.11610671936759	2.88868177666269e-06	0.000245345372231218
GO:1990948	ubiquitin ligase inhibitor activity	8/2277	11/18639	0.727272727272727	5.95328781890047	5.74473893601569e-06	0.000457424837780249
GO:0005085	guanyl-nucleotide exchange factor activity	51/2277	230/18639	0.221739130434783	1.81510568826259	1.49271397675468e-05	0.00105760513051773
GO:0004129	cytochrome-c oxidase activity	9/2277	15/18639	0.6	4.91146245059288	1.49426156588062e-05	0.00105760513051773
GO:0005096	GTPase activator activity	57/2277	271/18639	0.210332103321033	1.72173037935913	2.51988431304344e-05	0.00168964874464071
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	19/2277	59/18639	0.322033898305085	2.63609566557245	4.53645071879687e-05	0.0028897191078736
GO:0019843	rRNA binding	20/2277	65/18639	0.307692307692308	2.51869869261174	6.00771970575238e-05	0.00364468328815645
GO:0016209	antioxidant activity	24/2277	86/18639	0.27906976744186	2.28440113981064	6.77133776504276e-05	0.00392122014212022
GO:0004601	peroxidase activity	18/2277	57/18639	0.315789473684211	2.58498023715415	9.52129257898849e-05	0.00527396815027449
GO:0015252	proton channel activity	11/2277	27/18639	0.407407407407407	3.33494363929147	0.000176469517728818	0.00936759023277143
GO:0055106	ubiquitin-protein transferase regulator activity	13/2277	36/18639	0.361111111111111	2.95597277119016	0.000196827237981906	0.0100303160475579
GO:0048027	mRNA 5'-UTR binding	10/2277	24/18639	0.416666666666667	3.41073781291173	0.000279755670226358	0.0137080278410915
GO:0051020	GTPase binding	60/2277	315/18639	0.19047619047619	1.55919442875965	0.000293251755360353	0.0138371383825589
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	8/2277	17/18639	0.470588235294118	3.85212741222971	0.000428256988404611	0.018374407166784
GO:0019198	transmembrane receptor protein phosphatase activity	8/2277	17/18639	0.470588235294118	3.85212741222971	0.000428256988404611	0.018374407166784
GO:0031720	haptoglobin binding	6/2277	10/18639	0.6	4.91146245059288	0.000447100959317351	0.018374407166784
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	6/2277	10/18639	0.6	4.91146245059288	0.000447100959317351	0.018374407166784
GO:0031625	ubiquitin protein ligase binding	57/2277	302/18639	0.188741721854305	1.54499646624611	0.00051893171307306	0.0206599688267212
GO:0035091	phosphatidylinositol binding	54/2277	284/18639	0.190140845070423	1.55644936814563	0.000598123657272632	0.0230911981625858
GO:0005344	oxygen carrier activity	7/2277	14/18639	0.5	4.09288537549407	0.000630954290647195	0.0236422284201331
GO:0016791	phosphatase activity	52/2277	273/18639	0.19047619047619	1.55919442875965	0.00071618679600997	0.0260691993747629
GO:0019902	phosphatase binding	39/2277	190/18639	0.205263157894737	1.6802371541502	0.00073943238813103	0.0261676906244148
GO:0022804	active transmembrane transporter activity	79/2277	457/18639	0.172866520787746	1.41504570968942	0.000856151353157405	0.0294793736195279
GO:0031267	small GTPase binding	53/2277	283/18639	0.187279151943463	1.53302420424866	0.000960254591519519	0.0321937986735755
GO:0031386	protein tag activity	7/2277	15/18639	0.466666666666667	3.82002635046113	0.00105865819392238	0.0337182634764279
GO:0141047	molecular tag activity	7/2277	15/18639	0.466666666666667	3.82002635046113	0.00105865819392238	0.0337182634764279
GO:0017124	SH3 domain binding	26/2277	115/18639	0.226086956521739	1.85069599587558	0.00127674799616373	0.0396726084661609
GO:0044389	ubiquitin-like protein ligase binding	58/2277	322/18639	0.180124223602484	1.47445560110967	0.00150238557064382	0.0455723623095294
GO:0042578	phosphoric ester hydrolase activity	64/2277	363/18639	0.176308539944904	1.44322128943042	0.00154234853020254	0.0456965587785591
GO:0003714	transcription corepressor activity	40/2277	204/18639	0.196078431372549	1.60505308842905	0.00159507204015286	0.0461845858898805
GO:0004721	phosphoprotein phosphatase activity	35/2277	175/18639	0.2	1.63715415019763	0.00213557389441072	0.0597826274683128
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	16/2277	61/18639	0.262295081967213	2.14708741009525	0.00215855640780407	0.0597826274683128
GO:0005543	phospholipid binding	82/2277	497/18639	0.164989939637827	1.35056982209462	0.00271015675816756	0.0734625470192653
GO:0017147	Wnt-protein binding	10/2277	31/18639	0.32258064516129	2.64057120999617	0.00283216568128945	0.0751703974575575
GO:0003712	transcription coregulator activity	81/2277	495/18639	0.163636363636364	1.33948975925261	0.00358346942666589	0.0931702050933131
GO:0140789	histone phosphatase activity	28/2277	136/18639	0.205882352941176	1.6853057428505	0.00368136473240391	0.0938011733816516
GO:0008239	dipeptidyl-peptidase activity	5/2277	10/18639	0.5	4.09288537549407	0.00401199169788363	0.098889278657313
GO:0032266	phosphatidylinositol-3-phosphate binding	13/2277	48/18639	0.270833333333333	2.21697957839262	0.00403629708805359	0.098889278657313
GO:0046966	nuclear thyroid hormone receptor binding	9/2277	28/18639	0.321428571428571	2.6311405985319	0.00468089394326054	0.112518092145546
GO:0048407	platelet-derived growth factor binding	5/2277	11/18639	0.454545454545455	3.72080488681279	0.00662042110949672	0.156192898027756
GO:0044325	transmembrane transporter binding	27/2277	136/18639	0.198529411764706	1.62511625203441	0.00712474182972611	0.165034928928565
GO:0140312	cargo adaptor activity	7/2277	21/18639	0.333333333333333	2.72859025032938	0.00987753769113241	0.220670705568524
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	19/2277	89/18639	0.213483146067416	1.74752409290758	0.0102136830238018	0.220670705568524
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	19/2277	89/18639	0.213483146067416	1.74752409290758	0.0102136830238018	0.220670705568524
GO:0034452	dynactin binding	5/2277	12/18639	0.416666666666667	3.41073781291173	0.0102194439784481	0.220670705568524
GO:0140793	histone H2AXY142 phosphatase activity	19/2277	90/18639	0.211111111111111	1.72810715854194	0.0115038474905945	0.244265028383624
GO:0051117	ATPase binding	18/2277	84/18639	0.214285714285714	1.7540937323546	0.0117452314297755	0.245302046582524
GO:0004550	nucleoside diphosphate kinase activity	6/2277	17/18639	0.352941176470588	2.88909555917229	0.0123504123924253	0.249752783935711
GO:0015278	intracellularly gated calcium channel activity	6/2277	17/18639	0.352941176470588	2.88909555917229	0.0123504123924253	0.249752783935711
GO:0140517	protein-RNA adaptor activity	7/2277	22/18639	0.318181818181818	2.60456342076895	0.0129884581666381	0.258551495379639
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	57/2277	349/18639	0.163323782234957	1.33693103955967	0.0133910648686446	0.262464871425434
GO:0016922	nuclear receptor binding	26/2277	137/18639	0.18978102189781	1.55350393814373	0.0144828597420145	0.279053815052353
GO:0070700	BMP receptor binding	5/2277	13/18639	0.384615384615385	3.14837336576467	0.0149595002694531	0.279053815052353
GO:0140297	DNA-binding transcription factor binding	76/2277	488/18639	0.155737704918033	1.27483314974406	0.0151319013546182	0.279053815052353
GO:0031491	nucleosome binding	16/2277	74/18639	0.216216216216216	1.76989637859203	0.0155520037360515	0.279053815052353
GO:0030145	manganese ion binding	15/2277	68/18639	0.220588235294118	1.80568472448268	0.01574107537848	0.279053815052353
GO:1901981	phosphatidylinositol phosphate binding	33/2277	185/18639	0.178378378378378	1.46016451233843	0.0160951805107392	0.279053815052353
GO:0051219	phosphoprotein binding	19/2277	93/18639	0.204301075268817	1.67236176633091	0.0161640998532496	0.279053815052353
GO:0004706	JUN kinase kinase kinase activity	6/2277	18/18639	0.333333333333333	2.72859025032938	0.0166468523893084	0.279053815052353
GO:0035615	clathrin adaptor activity	6/2277	18/18639	0.333333333333333	2.72859025032938	0.0166468523893084	0.279053815052353
GO:0070064	proline-rich region binding	6/2277	18/18639	0.333333333333333	2.72859025032938	0.0166468523893084	0.279053815052353
GO:1990381	ubiquitin-specific protease binding	6/2277	18/18639	0.333333333333333	2.72859025032938	0.0166468523893084	0.279053815052353
GO:0004715	non-membrane spanning protein tyrosine kinase activity	11/2277	45/18639	0.244444444444444	2.00096618357488	0.0173222814715768	0.286605020711544
GO:0016504	peptidase activator activity	13/2277	57/18639	0.228070175438596	1.866930171278	0.0180947058708196	0.29554686255672
GO:0045296	cadherin binding	54/2277	334/18639	0.161676646706587	1.32344796572862	0.0188875500326818	0.30459162964097
GO:0019787	ubiquitin-like protein transferase activity	74/2277	479/18639	0.154488517745303	1.26460758992301	0.0194239294067216	0.309326075802042
GO:0019763	immunoglobulin receptor activity	5/2277	14/18639	0.357142857142857	2.92348955392434	0.0209710817361021	0.325504736754082
GO:0032036	myosin heavy chain binding	5/2277	14/18639	0.357142857142857	2.92348955392434	0.0209710817361021	0.325504736754082
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	7/2277	24/18639	0.291666666666667	2.38751646903821	0.0212063525514826	0.325504736754082
GO:0016755	aminoacyltransferase activity	76/2277	496/18639	0.153225806451613	1.25427132474818	0.0215290017652094	0.32652319343901
GO:0005345	purine nucleobase transmembrane transporter activity	4/2277	10/18639	0.4	3.27430830039526	0.0253900961892785	0.363449242080233
GO:0005522	profilin binding	4/2277	10/18639	0.4	3.27430830039526	0.0253900961892785	0.363449242080233
GO:0015924	mannosyl-oligosaccharide mannosidase activity	4/2277	10/18639	0.4	3.27430830039526	0.0253900961892785	0.363449242080233
GO:0047429	nucleoside triphosphate diphosphatase activity	4/2277	10/18639	0.4	3.27430830039526	0.0253900961892785	0.363449242080233
GO:0097177	mitochondrial ribosome binding	4/2277	10/18639	0.4	3.27430830039526	0.0253900961892785	0.363449242080233
GO:0004709	MAP kinase kinase kinase activity	7/2277	25/18639	0.28	2.29201581027668	0.0264301295809027	0.371554768604525
GO:0048487	beta-tubulin binding	10/2277	42/18639	0.238095238095238	1.94899303594956	0.02705420584624	0.371554768604525
GO:0004725	protein tyrosine phosphatase activity	19/2277	98/18639	0.193877551020408	1.58703718641607	0.0270566369686454	0.371554768604525
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	12/2277	54/18639	0.222222222222222	1.81906016688625	0.0274145590650121	0.371554768604525
GO:0051287	NAD binding	12/2277	54/18639	0.222222222222222	1.81906016688625	0.0274145590650121	0.371554768604525
GO:0015929	hexosaminidase activity	5/2277	15/18639	0.333333333333333	2.72859025032938	0.0283606306442231	0.376369202507711
GO:0017081	chloride channel regulator activity	5/2277	15/18639	0.333333333333333	2.72859025032938	0.0283606306442231	0.376369202507711
GO:0008200	ion channel inhibitor activity	10/2277	43/18639	0.232558139534884	1.90366761650887	0.0315182231233668	0.41396099236257
GO:0034237	protein kinase A regulatory subunit binding	7/2277	26/18639	0.269230769230769	2.20386135603527	0.032465302015406	0.419967524270505
GO:0005201	extracellular matrix structural constituent	29/2277	168/18639	0.172619047619048	1.41301995106343	0.0339720122660679	0.419967524270505
GO:0009931	calcium-dependent protein serine/threonine kinase activity	6/2277	21/18639	0.285714285714286	2.33879164313947	0.0353813322366915	0.419967524270505
GO:0072542	protein phosphatase activator activity	6/2277	21/18639	0.285714285714286	2.33879164313947	0.0353813322366915	0.419967524270505
GO:0008046	axon guidance receptor activity	4/2277	11/18639	0.363636363636364	2.97664390945023	0.0361156248062966	0.419967524270505
GO:0008172	S-methyltransferase activity	4/2277	11/18639	0.363636363636364	2.97664390945023	0.0361156248062966	0.419967524270505
GO:0015205	nucleobase transmembrane transporter activity	4/2277	11/18639	0.363636363636364	2.97664390945023	0.0361156248062966	0.419967524270505
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	4/2277	11/18639	0.363636363636364	2.97664390945023	0.0361156248062966	0.419967524270505
GO:0019864	IgG binding	4/2277	11/18639	0.363636363636364	2.97664390945023	0.0361156248062966	0.419967524270505
GO:0140031	phosphorylation-dependent protein binding	4/2277	11/18639	0.363636363636364	2.97664390945023	0.0361156248062966	0.419967524270505
GO:0016248	channel inhibitor activity	10/2277	44/18639	0.227272727272727	1.8604024434064	0.0364756401818783	0.419967524270505
GO:0019205	nucleobase-containing compound kinase activity	10/2277	44/18639	0.227272727272727	1.8604024434064	0.0364756401818783	0.419967524270505
GO:0030020	extracellular matrix structural constituent conferring tensile strength	10/2277	44/18639	0.227272727272727	1.8604024434064	0.0364756401818783	0.419967524270505
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	23/2277	128/18639	0.1796875	1.47088068181818	0.0365905770753737	0.419967524270505
GO:0043023	ribosomal large subunit binding	5/2277	16/18639	0.3125	2.55805335968379	0.0372080052741432	0.423241059993379
GO:0004364	glutathione transferase activity	7/2277	27/18639	0.259259259259259	2.1222368613673	0.0393541791457028	0.439800212558117
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	7/2277	27/18639	0.259259259259259	2.1222368613673	0.0393541791457028	0.439800212558117
GO:0141110	transporter inhibitor activity	10/2277	45/18639	0.222222222222222	1.81906016688625	0.0419480283848216	0.458133421814769
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	16/2277	83/18639	0.192771084337349	1.57797990380494	0.0420377505510741	0.458133421814769
GO:0016776	phosphotransferase activity, phosphate group as acceptor	9/2277	39/18639	0.230769230769231	1.8890240194588	0.0420734775136012	0.458133421814769
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	6/2277	22/18639	0.272727272727273	2.23248293208768	0.0437786600129616	0.468689183668177
GO:0061133	endopeptidase activator activity	6/2277	22/18639	0.272727272727273	2.23248293208768	0.0437786600129616	0.468689183668177
GO:0046875	ephrin receptor binding	7/2277	28/18639	0.25	2.04644268774704	0.047131053286578	0.473539190837586
GO:0051019	mitogen-activated protein kinase binding	7/2277	28/18639	0.25	2.04644268774704	0.047131053286578	0.473539190837586
GO:1990226	histone methyltransferase binding	5/2277	17/18639	0.294117647058824	2.40757963264357	0.0475653356415257	0.473539190837586
GO:0015035	protein-disulfide reductase activity	8/2277	34/18639	0.235294117647059	1.92606370611486	0.0485006555395742	0.473539190837586
GO:0052866	phosphatidylinositol phosphate phosphatase activity	8/2277	34/18639	0.235294117647059	1.92606370611486	0.0485006555395742	0.473539190837586
GO:0030331	nuclear estrogen receptor binding	9/2277	40/18639	0.225	1.84179841897233	0.0486243006028357	0.473539190837586
GO:0004875	complement receptor activity	4/2277	12/18639	0.333333333333333	2.72859025032938	0.0490637152202208	0.473539190837586
GO:0005049	nuclear export signal receptor activity	4/2277	12/18639	0.333333333333333	2.72859025032938	0.0490637152202208	0.473539190837586
GO:0016208	AMP binding	4/2277	12/18639	0.333333333333333	2.72859025032938	0.0490637152202208	0.473539190837586
GO:0035497	cAMP response element binding	4/2277	12/18639	0.333333333333333	2.72859025032938	0.0490637152202208	0.473539190837586
GO:0097371	MDM2/MDM4 family protein binding	4/2277	12/18639	0.333333333333333	2.72859025032938	0.0490637152202208	0.473539190837586
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	4/2277	12/18639	0.333333333333333	2.72859025032938	0.0490637152202208	0.473539190837586
GO:1990247	N6-methyladenosine-containing RNA reader activity	4/2277	12/18639	0.333333333333333	2.72859025032938	0.0490637152202208	0.473539190837586
GO:0016874	ligase activity	28/2277	167/18639	0.167664670658683	1.3724645570519	0.0505193459104924	0.482738485985414
GO:0045309	protein phosphorylated amino acid binding	12/2277	59/18639	0.203389830508475	1.66490252562471	0.05077469161856	0.482738485985414
GO:0031681	G-protein beta-subunit binding	6/2277	23/18639	0.260869565217391	2.13541845677952	0.0533201601481322	0.495838569552703
GO:0042171	lysophosphatidic acid acyltransferase activity	6/2277	23/18639	0.260869565217391	2.13541845677952	0.0533201601481322	0.495838569552703
GO:0071617	lysophospholipid acyltransferase activity	6/2277	23/18639	0.260869565217391	2.13541845677952	0.0533201601481322	0.495838569552703
GO:0003785	actin monomer binding	7/2277	29/18639	0.241379310344828	1.97587569851438	0.0558216448951799	0.515338953597531
GO:0042826	histone deacetylase binding	22/2277	127/18639	0.173228346456693	1.41800753166724	0.0568365612606582	0.520933662202004
GO:0003713	transcription coactivator activity	40/2277	256/18639	0.15625	1.2790266798419	0.0605259405949212	0.52108793634309
GO:0038187	pattern recognition receptor activity	10/2277	48/18639	0.208333333333333	1.70536890645586	0.0616326596040768	0.52108793634309
GO:0016859	cis-trans isomerase activity	9/2277	42/18639	0.214285714285714	1.7540937323546	0.0636579665617279	0.52108793634309
GO:0019894	kinesin binding	9/2277	42/18639	0.214285714285714	1.7540937323546	0.0636579665617279	0.52108793634309
GO:0035325	Toll-like receptor binding	4/2277	13/18639	0.307692307692308	2.51869869261174	0.0642211440872288	0.52108793634309
GO:0035673	oligopeptide transmembrane transporter activity	4/2277	13/18639	0.307692307692308	2.51869869261174	0.0642211440872288	0.52108793634309
GO:0033192	calmodulin-dependent protein phosphatase activity	15/2277	81/18639	0.185185185185185	1.51588347240521	0.0645366822098008	0.52108793634309
GO:0140791	histone H2AXS140 phosphatase activity	15/2277	81/18639	0.185185185185185	1.51588347240521	0.0645366822098008	0.52108793634309
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	15/2277	81/18639	0.185185185185185	1.51588347240521	0.0645366822098008	0.52108793634309
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	15/2277	81/18639	0.185185185185185	1.51588347240521	0.0645366822098008	0.52108793634309
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	15/2277	81/18639	0.185185185185185	1.51588347240521	0.0645366822098008	0.52108793634309
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	15/2277	81/18639	0.185185185185185	1.51588347240521	0.0645366822098008	0.52108793634309
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	15/2277	81/18639	0.185185185185185	1.51588347240521	0.0645366822098008	0.52108793634309
GO:1990439	MAP kinase serine/threonine phosphatase activity	15/2277	81/18639	0.185185185185185	1.51588347240521	0.0645366822098008	0.52108793634309
GO:0035401	histone H3Y41 kinase activity	20/2277	115/18639	0.173913043478261	1.42361230451968	0.064742109960647	0.52108793634309
GO:0140801	histone H2AXY142 kinase activity	20/2277	115/18639	0.173913043478261	1.42361230451968	0.064742109960647	0.52108793634309
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	8/2277	36/18639	0.222222222222222	1.81906016688625	0.0650721844361931	0.52108793634309
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	8/2277	36/18639	0.222222222222222	1.81906016688625	0.0650721844361931	0.52108793634309
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	8/2277	36/18639	0.222222222222222	1.81906016688625	0.0650721844361931	0.52108793634309
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	7/2277	30/18639	0.233333333333333	1.91001317523057	0.0654427549567459	0.52108793634309
GO:0033612	receptor serine/threonine kinase binding	7/2277	30/18639	0.233333333333333	1.91001317523057	0.0654427549567459	0.52108793634309
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	15/2277	82/18639	0.182926829268293	1.49739708859539	0.0704569723513304	0.554087547997499
GO:0033549	MAP kinase phosphatase activity	15/2277	82/18639	0.182926829268293	1.49739708859539	0.0704569723513304	0.554087547997499
GO:0004722	protein serine/threonine phosphatase activity	18/2277	103/18639	0.174757281553398	1.43052304386201	0.0738640599743435	0.577317867529531
GO:0003707	nuclear steroid receptor activity	6/2277	25/18639	0.24	1.96458498023715	0.0758967520801738	0.586014922122069
GO:0019211	phosphatase activator activity	6/2277	25/18639	0.24	1.96458498023715	0.0758967520801738	0.586014922122069
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	4/2277	14/18639	0.285714285714286	2.33879164313947	0.0815211690276795	0.616425009286112
GO:0042813	Wnt receptor activity	4/2277	14/18639	0.285714285714286	2.33879164313947	0.0815211690276795	0.616425009286112
GO:0046030	inositol trisphosphate phosphatase activity	4/2277	14/18639	0.285714285714286	2.33879164313947	0.0815211690276795	0.616425009286112
GO:0015932	nucleobase-containing compound transmembrane transporter activity	11/2277	57/18639	0.192982456140351	1.57971014492754	0.0817706644971374	0.616425009286112
GO:0016247	channel regulator activity	27/2277	168/18639	0.160714285714286	1.31557029926595	0.0822583680006476	0.616453887251912
GO:0017018	myosin phosphatase activity	15/2277	84/18639	0.178571428571429	1.46174477696217	0.0833475783399928	0.620963829269888
GO:0042887	amide transmembrane transporter activity	8/2277	38/18639	0.210526315789474	1.72332015810277	0.0847580962121421	0.624970173549027
GO:0004713	protein tyrosine kinase activity	23/2277	140/18639	0.164285714285714	1.34480519480519	0.0848664364395461	0.624970173549027
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	5/2277	20/18639	0.25	2.04644268774704	0.0878097187352145	0.642928630279674
GO:0050681	nuclear androgen receptor binding	6/2277	26/18639	0.230769230769231	1.8890240194588	0.0889261870996042	0.643704331618726
GO:0050750	low-density lipoprotein particle receptor binding	6/2277	26/18639	0.230769230769231	1.8890240194588	0.0889261870996042	0.643704331618726
GO:0052689	carboxylic ester hydrolase activity	16/2277	92/18639	0.173913043478261	1.42361230451968	0.0911617198714288	0.656158367888138
GO:0141108	transporter regulator activity	27/2277	170/18639	0.158823529411765	1.30009300162753	0.0919323423858625	0.657987664042634
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	8/2277	39/18639	0.205128205128205	1.67913246174116	0.0957734816827333	0.678899205747814
GO:0005080	protein kinase C binding	10/2277	52/18639	0.192307692307692	1.57418668288234	0.0959198249879172	0.678899205747814
GO:0004879	nuclear receptor activity	11/2277	59/18639	0.186440677966102	1.52616064848931	0.0993704137672322	0.679819031436264
GO:0070063	RNA polymerase binding	11/2277	59/18639	0.186440677966102	1.52616064848931	0.0993704137672322	0.679819031436264
GO:0140416	transcription regulator inhibitor activity	7/2277	33/18639	0.212121212121212	1.73637561384597	0.0999215588923394	0.679819031436264
GO:0061659	ubiquitin-like protein ligase activity	54/2277	372/18639	0.145161290322581	1.18825704449828	0.100780090399362	0.679819031436264
GO:0004559	alpha-mannosidase activity	4/2277	15/18639	0.266666666666667	2.1828722002635	0.100852273894391	0.679819031436264
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	4/2277	15/18639	0.266666666666667	2.1828722002635	0.100852273894391	0.679819031436264
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	4/2277	15/18639	0.266666666666667	2.1828722002635	0.100852273894391	0.679819031436264
GO:0005523	tropomyosin binding	4/2277	15/18639	0.266666666666667	2.1828722002635	0.100852273894391	0.679819031436264
GO:0120283	protein serine/threonine kinase binding	4/2277	15/18639	0.266666666666667	2.1828722002635	0.100852273894391	0.679819031436264
GO:0019838	growth factor binding	22/2277	136/18639	0.161764705882353	1.32416879795396	0.102556317307781	0.68762394377024
GO:0005044	scavenger receptor activity	6/2277	27/18639	0.222222222222222	1.81906016688625	0.103089617943576	0.68762394377024
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	5/2277	21/18639	0.238095238095238	1.94899303594956	0.104193589516003	0.687785663437242
GO:0010314	phosphatidylinositol-5-phosphate binding	5/2277	21/18639	0.238095238095238	1.94899303594956	0.104193589516003	0.687785663437242
GO:0004842	ubiquitin-protein transferase activity	64/2277	449/18639	0.142538975501114	1.16679137653283	0.105186382728706	0.690585136309562
GO:0005246	calcium channel regulator activity	10/2277	53/18639	0.188679245283019	1.54448504735625	0.105954183583183	0.690585136309562
GO:0016853	isomerase activity	28/2277	180/18639	0.155555555555556	1.27334211682038	0.106243867124548	0.690585136309562
GO:0015036	disulfide oxidoreductase activity	8/2277	40/18639	0.2	1.63715415019763	0.107560776952708	0.693689787582545
GO:0098531	ligand-modulated transcription factor activity	11/2277	60/18639	0.183333333333333	1.50072463768116	0.108949176011546	0.693689787582545
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	12/2277	67/18639	0.17910447761194	1.46610819420683	0.111000024608402	0.693689787582545
GO:0001784	phosphotyrosine residue binding	9/2277	47/18639	0.191489361702128	1.56748801614667	0.112887133973638	0.693689787582545
GO:0019825	oxygen binding	7/2277	34/18639	0.205882352941176	1.6853057428505	0.113252904206019	0.693689787582545
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	3/2277	10/18639	0.3	2.45573122529644	0.113255475523681	0.693689787582545
GO:0005031	tumor necrosis factor receptor activity	3/2277	10/18639	0.3	2.45573122529644	0.113255475523681	0.693689787582545
GO:0016303	1-phosphatidylinositol-3-kinase activity	3/2277	10/18639	0.3	2.45573122529644	0.113255475523681	0.693689787582545
GO:0030957	Tat protein binding	3/2277	10/18639	0.3	2.45573122529644	0.113255475523681	0.693689787582545
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	3/2277	10/18639	0.3	2.45573122529644	0.113255475523681	0.693689787582545
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	3/2277	10/18639	0.3	2.45573122529644	0.113255475523681	0.693689787582545
GO:1990757	ubiquitin ligase activator activity	3/2277	10/18639	0.3	2.45573122529644	0.113255475523681	0.693689787582545
GO:0099106	ion channel regulator activity	25/2277	160/18639	0.15625	1.2790266798419	0.116896387696052	0.703680526465396
GO:0019789	SUMO transferase activity	6/2277	28/18639	0.214285714285714	1.7540937323546	0.118351044668212	0.703680526465396
GO:0019208	phosphatase regulator activity	19/2277	117/18639	0.162393162393162	1.32931319887842	0.11893217503296	0.703680526465396
GO:0042169	SH2 domain binding	8/2277	41/18639	0.195121951219512	1.59722356116842	0.120105376565179	0.703680526465396
GO:0061650	ubiquitin-like protein conjugating enzyme activity	8/2277	41/18639	0.195121951219512	1.59722356116842	0.120105376565179	0.703680526465396
GO:0034062	5'-3' RNA polymerase activity	5/2277	22/18639	0.227272727272727	1.8604024434064	0.121962686428662	0.703680526465396
GO:0097747	RNA polymerase activity	5/2277	22/18639	0.227272727272727	1.8604024434064	0.121962686428662	0.703680526465396
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	4/2277	16/18639	0.25	2.04644268774704	0.12206703010114	0.703680526465396
GO:0004707	MAP kinase activity	4/2277	16/18639	0.25	2.04644268774704	0.12206703010114	0.703680526465396
GO:0004708	MAP kinase kinase activity	4/2277	16/18639	0.25	2.04644268774704	0.12206703010114	0.703680526465396
GO:0015562	efflux transmembrane transporter activity	4/2277	16/18639	0.25	2.04644268774704	0.12206703010114	0.703680526465396
GO:0015923	mannosidase activity	4/2277	16/18639	0.25	2.04644268774704	0.12206703010114	0.703680526465396
GO:0017070	U6 snRNA binding	4/2277	16/18639	0.25	2.04644268774704	0.12206703010114	0.703680526465396
GO:0005154	epidermal growth factor receptor binding	7/2277	35/18639	0.2	1.63715415019763	0.127465857470819	0.73149325413434
GO:0019210	kinase inhibitor activity	15/2277	90/18639	0.166666666666667	1.36429512516469	0.130567529385628	0.733008176892941
GO:0030165	PDZ domain binding	14/2277	83/18639	0.168674698795181	1.38073241582933	0.13102177473149	0.733008176892941
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	6/2277	29/18639	0.206896551724138	1.69360774158375	0.134663062000307	0.733008176892941
GO:0099604	ligand-gated calcium channel activity	6/2277	29/18639	0.206896551724138	1.69360774158375	0.134663062000307	0.733008176892941
GO:0043022	ribosome binding	18/2277	112/18639	0.160714285714286	1.31557029926595	0.135700265892186	0.733008176892941
GO:0001222	transcription corepressor binding	9/2277	49/18639	0.183673469387755	1.5035089134468	0.137177101515821	0.733008176892941
GO:0060590	ATPase regulator activity	9/2277	49/18639	0.183673469387755	1.5035089134468	0.137177101515821	0.733008176892941
GO:0004860	protein kinase inhibitor activity	14/2277	84/18639	0.166666666666667	1.36429512516469	0.140556614009789	0.733008176892941
GO:0004602	glutathione peroxidase activity	5/2277	23/18639	0.217391304347826	1.7795153806496	0.14103005483992	0.733008176892941
GO:0017134	fibroblast growth factor binding	5/2277	23/18639	0.217391304347826	1.7795153806496	0.14103005483992	0.733008176892941
GO:0070577	lysine-acetylated histone binding	5/2277	23/18639	0.217391304347826	1.7795153806496	0.14103005483992	0.733008176892941
GO:0140103	catalytic activity, acting on a glycoprotein	5/2277	23/18639	0.217391304347826	1.7795153806496	0.14103005483992	0.733008176892941
GO:0002162	dystroglycan binding	3/2277	11/18639	0.272727272727273	2.23248293208768	0.1421829195427	0.733008176892941
GO:0008526	phosphatidylinositol transfer activity	3/2277	11/18639	0.272727272727273	2.23248293208768	0.1421829195427	0.733008176892941
GO:0015217	ADP transmembrane transporter activity	3/2277	11/18639	0.272727272727273	2.23248293208768	0.1421829195427	0.733008176892941
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	3/2277	11/18639	0.272727272727273	2.23248293208768	0.1421829195427	0.733008176892941
GO:0032404	mismatch repair complex binding	3/2277	11/18639	0.272727272727273	2.23248293208768	0.1421829195427	0.733008176892941
GO:0032794	GTPase activating protein binding	3/2277	11/18639	0.272727272727273	2.23248293208768	0.1421829195427	0.733008176892941
GO:0034713	type I transforming growth factor beta receptor binding	3/2277	11/18639	0.272727272727273	2.23248293208768	0.1421829195427	0.733008176892941
GO:0035252	UDP-xylosyltransferase activity	3/2277	11/18639	0.272727272727273	2.23248293208768	0.1421829195427	0.733008176892941
GO:0042285	xylosyltransferase activity	3/2277	11/18639	0.272727272727273	2.23248293208768	0.1421829195427	0.733008176892941
GO:0140537	transcription regulator activator activity	3/2277	11/18639	0.272727272727273	2.23248293208768	0.1421829195427	0.733008176892941
GO:0044390	ubiquitin-like protein conjugating enzyme binding	7/2277	36/18639	0.194444444444444	1.59167764602547	0.142526399237798	0.733008176892941
GO:0004659	prenyltransferase activity	4/2277	17/18639	0.235294117647059	1.92606370611486	0.144990628396406	0.733008176892941
GO:0008429	phosphatidylethanolamine binding	4/2277	17/18639	0.235294117647059	1.92606370611486	0.144990628396406	0.733008176892941
GO:0016018	cyclosporin A binding	4/2277	17/18639	0.235294117647059	1.92606370611486	0.144990628396406	0.733008176892941
GO:0016805	dipeptidase activity	4/2277	17/18639	0.235294117647059	1.92606370611486	0.144990628396406	0.733008176892941
GO:0030169	low-density lipoprotein particle binding	4/2277	17/18639	0.235294117647059	1.92606370611486	0.144990628396406	0.733008176892941
GO:0046965	nuclear retinoid X receptor binding	4/2277	17/18639	0.235294117647059	1.92606370611486	0.144990628396406	0.733008176892941
GO:0070402	NADPH binding	4/2277	17/18639	0.235294117647059	1.92606370611486	0.144990628396406	0.733008176892941
GO:0048156	tau protein binding	8/2277	43/18639	0.186046511627907	1.5229340932071	0.147380622812711	0.742145903017367
GO:0015215	nucleotide transmembrane transporter activity	6/2277	30/18639	0.2	1.63715415019763	0.151968138761197	0.757283396209291
GO:0031624	ubiquitin conjugating enzyme binding	6/2277	30/18639	0.2	1.63715415019763	0.151968138761197	0.757283396209291
GO:0140299	molecular sensor activity	12/2277	71/18639	0.169014084507042	1.38351054946278	0.152169976004379	0.757283396209291
GO:0019213	deacetylase activity	7/2277	37/18639	0.189189189189189	1.54865933126803	0.158393764416321	0.770818815555086
GO:0019903	protein phosphatase binding	22/2277	144/18639	0.152777777777778	1.2506038647343	0.158646359178723	0.770818815555086
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	19/2277	122/18639	0.155737704918033	1.27483314974406	0.158807913473436	0.770818815555086
GO:0019207	kinase regulator activity	41/2277	287/18639	0.142857142857143	1.16939582156973	0.161263496017129	0.770818815555086
GO:0004622	lysophospholipase activity	5/2277	24/18639	0.208333333333333	1.70536890645586	0.161294605408229	0.770818815555086
GO:0005540	hyaluronic acid binding	5/2277	24/18639	0.208333333333333	1.70536890645586	0.161294605408229	0.770818815555086
GO:0015295	solute:proton symporter activity	5/2277	24/18639	0.208333333333333	1.70536890645586	0.161294605408229	0.770818815555086
GO:0035035	histone acetyltransferase binding	5/2277	24/18639	0.208333333333333	1.70536890645586	0.161294605408229	0.770818815555086
GO:0070840	dynein complex binding	5/2277	24/18639	0.208333333333333	1.70536890645586	0.161294605408229	0.770818815555086
GO:0140033	acetylation-dependent protein binding	5/2277	24/18639	0.208333333333333	1.70536890645586	0.161294605408229	0.770818815555086
GO:0046332	SMAD binding	13/2277	79/18639	0.164556962025316	1.3470255666183	0.162305055479528	0.770818815555086
GO:0005518	collagen binding	12/2277	72/18639	0.166666666666667	1.36429512516469	0.16355749586562	0.770818815555086
GO:0003743	translation initiation factor activity	9/2277	51/18639	0.176470588235294	1.44454777958614	0.163921714131511	0.770818815555086
GO:0016830	carbon-carbon lyase activity	9/2277	51/18639	0.176470588235294	1.44454777958614	0.163921714131511	0.770818815555086
GO:0038024	cargo receptor activity	11/2277	65/18639	0.169230769230769	1.38528428093645	0.164368134175173	0.770818815555086
GO:0008408	3'-5' exonuclease activity	10/2277	58/18639	0.172413793103448	1.41133978465313	0.164570422159328	0.770818815555086
GO:0000400	four-way junction DNA binding	4/2277	18/18639	0.222222222222222	1.81906016688625	0.16942879080415	0.777062188731263
GO:0016854	racemase and epimerase activity	4/2277	18/18639	0.222222222222222	1.81906016688625	0.16942879080415	0.777062188731263
GO:0016411	acylglycerol O-acyltransferase activity	6/2277	31/18639	0.193548387096774	1.5843427259977	0.170199984263014	0.777062188731263
GO:0070273	phosphatidylinositol-4-phosphate binding	6/2277	31/18639	0.193548387096774	1.5843427259977	0.170199984263014	0.777062188731263
GO:0070325	lipoprotein particle receptor binding	6/2277	31/18639	0.193548387096774	1.5843427259977	0.170199984263014	0.777062188731263
GO:0004300	enoyl-CoA hydratase activity	3/2277	12/18639	0.25	2.04644268774704	0.173222654316859	0.777062188731263
GO:0008179	adenylate cyclase binding	3/2277	12/18639	0.25	2.04644268774704	0.173222654316859	0.777062188731263
GO:0035014	phosphatidylinositol 3-kinase regulator activity	3/2277	12/18639	0.25	2.04644268774704	0.173222654316859	0.777062188731263
GO:0045295	gamma-catenin binding	3/2277	12/18639	0.25	2.04644268774704	0.173222654316859	0.777062188731263
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	3/2277	12/18639	0.25	2.04644268774704	0.173222654316859	0.777062188731263
GO:0070008	serine-type exopeptidase activity	3/2277	12/18639	0.25	2.04644268774704	0.173222654316859	0.777062188731263
GO:1990459	transferrin receptor binding	3/2277	12/18639	0.25	2.04644268774704	0.173222654316859	0.777062188731263
GO:0008238	exopeptidase activity	16/2277	102/18639	0.156862745098039	1.28404247074324	0.176540482984646	0.789166930955925
GO:0051539	4 iron, 4 sulfur cluster binding	8/2277	45/18639	0.177777777777778	1.455248133509	0.177377603020717	0.790136595274104
GO:0140767	enzyme-substrate adaptor activity	21/2277	139/18639	0.151079136690647	1.23669917820684	0.178469732677712	0.792231496276671
GO:0008276	protein methyltransferase activity	15/2277	95/18639	0.157894736842105	1.29249011857708	0.179466581171303	0.793890362542502
GO:0000030	mannosyltransferase activity	5/2277	25/18639	0.2	1.63715415019763	0.182644068740242	0.802374288189893
GO:0042974	nuclear retinoic acid receptor binding	5/2277	25/18639	0.2	1.63715415019763	0.182644068740242	0.802374288189893
GO:0035173	histone kinase activity	50/2277	360/18639	0.138888888888889	1.13691260430391	0.183667400544451	0.804097141902511
GO:0061630	ubiquitin protein ligase activity	49/2277	353/18639	0.138810198300283	1.13626846118532	0.187556622151026	0.818312111713724
GO:0022884	macromolecule transmembrane transporter activity	6/2277	32/18639	0.1875	1.53483201581028	0.189284959002701	0.820234822345039
GO:0120015	sterol transfer activity	6/2277	32/18639	0.1875	1.53483201581028	0.189284959002701	0.820234822345039
GO:0016860	intramolecular oxidoreductase activity	9/2277	53/18639	0.169811320754717	1.39003654262063	0.192922948509786	0.829206154867878
GO:0051018	protein kinase A binding	9/2277	53/18639	0.169811320754717	1.39003654262063	0.192922948509786	0.829206154867878
GO:0004180	carboxypeptidase activity	8/2277	46/18639	0.173913043478261	1.42361230451968	0.193307871268257	0.829206154867878
GO:0050145	nucleoside monophosphate kinase activity	4/2277	19/18639	0.210526315789474	1.72332015810277	0.19517488901854	0.82995851695126
GO:0140036	ubiquitin-modified protein reader activity	4/2277	19/18639	0.210526315789474	1.72332015810277	0.19517488901854	0.82995851695126
GO:0051015	actin filament binding	30/2277	209/18639	0.143540669856459	1.17499101688825	0.197426251641193	0.82995851695126
GO:0019887	protein kinase regulator activity	36/2277	255/18639	0.141176470588235	1.15563822366891	0.19915306789651	0.82995851695126
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	5/2277	26/18639	0.192307692307692	1.57418668288234	0.204957850083252	0.82995851695126
GO:0008143	poly(A) binding	5/2277	26/18639	0.192307692307692	1.57418668288234	0.204957850083252	0.82995851695126
GO:0008198	ferrous iron binding	5/2277	26/18639	0.192307692307692	1.57418668288234	0.204957850083252	0.82995851695126
GO:0015216	purine nucleotide transmembrane transporter activity	5/2277	26/18639	0.192307692307692	1.57418668288234	0.204957850083252	0.82995851695126
GO:0019865	immunoglobulin binding	5/2277	26/18639	0.192307692307692	1.57418668288234	0.204957850083252	0.82995851695126
GO:0070006	metalloaminopeptidase activity	5/2277	26/18639	0.192307692307692	1.57418668288234	0.204957850083252	0.82995851695126
GO:0002161	aminoacyl-tRNA editing activity	3/2277	13/18639	0.230769230769231	1.8890240194588	0.205923107385749	0.82995851695126
GO:0004535	poly(A)-specific ribonuclease activity	3/2277	13/18639	0.230769230769231	1.8890240194588	0.205923107385749	0.82995851695126
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	3/2277	13/18639	0.230769230769231	1.8890240194588	0.205923107385749	0.82995851695126
GO:0005035	death receptor activity	3/2277	13/18639	0.230769230769231	1.8890240194588	0.205923107385749	0.82995851695126
GO:0019855	calcium channel inhibitor activity	3/2277	13/18639	0.230769230769231	1.8890240194588	0.205923107385749	0.82995851695126
GO:0039706	co-receptor binding	3/2277	13/18639	0.230769230769231	1.8890240194588	0.205923107385749	0.82995851695126
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	3/2277	13/18639	0.230769230769231	1.8890240194588	0.205923107385749	0.82995851695126
GO:0045159	myosin II binding	3/2277	13/18639	0.230769230769231	1.8890240194588	0.205923107385749	0.82995851695126
GO:0061459	L-arginine transmembrane transporter activity	3/2277	13/18639	0.230769230769231	1.8890240194588	0.205923107385749	0.82995851695126
GO:0050661	NADP binding	9/2277	54/18639	0.166666666666667	1.36429512516469	0.208194188217871	0.82995851695126
GO:0061749	forked DNA-dependent helicase activity	8/2277	47/18639	0.170212765957447	1.39332268101926	0.209804432764589	0.82995851695126
GO:1990518	single-stranded 3'-5' DNA helicase activity	8/2277	47/18639	0.170212765957447	1.39332268101926	0.209804432764589	0.82995851695126
GO:0004177	aminopeptidase activity	7/2277	40/18639	0.175	1.43250988142292	0.210343599944929	0.82995851695126
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	7/2277	40/18639	0.175	1.43250988142292	0.210343599944929	0.82995851695126
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	7/2277	40/18639	0.175	1.43250988142292	0.210343599944929	0.82995851695126
GO:0140996	histone H3 kinase activity	49/2277	357/18639	0.137254901960784	1.12353716190033	0.210421193858129	0.82995851695126
GO:0051536	iron-sulfur cluster binding	12/2277	76/18639	0.157894736842105	1.29249011857708	0.213085861341049	0.837874652310175
GO:0004527	exonuclease activity	13/2277	84/18639	0.154761904761905	1.26684547336721	0.221733482370988	0.859722235090759
GO:0016505	peptidase activator activity involved in apoptotic process	4/2277	20/18639	0.2	1.63715415019763	0.222016181589372	0.859722235090759
GO:0052745	inositol phosphate phosphatase activity	4/2277	20/18639	0.2	1.63715415019763	0.222016181589372	0.859722235090759
GO:0140664	ATP-dependent DNA damage sensor activity	4/2277	20/18639	0.2	1.63715415019763	0.222016181589372	0.859722235090759
GO:0140939	histone H4 methyltransferase activity	4/2277	20/18639	0.2	1.63715415019763	0.222016181589372	0.859722235090759
GO:0051540	metal cluster binding	12/2277	77/18639	0.155844155844156	1.27570453262153	0.226375064083491	0.862860063636893
GO:0009378	four-way junction helicase activity	8/2277	48/18639	0.166666666666667	1.36429512516469	0.22682230139803	0.862860063636893
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	8/2277	48/18639	0.166666666666667	1.36429512516469	0.22682230139803	0.862860063636893
GO:0036121	double-stranded DNA helicase activity	8/2277	48/18639	0.166666666666667	1.36429512516469	0.22682230139803	0.862860063636893
GO:0043138	3'-5' DNA helicase activity	8/2277	48/18639	0.166666666666667	1.36429512516469	0.22682230139803	0.862860063636893
GO:0001671	ATPase activator activity	5/2277	27/18639	0.185185185185185	1.51588347240521	0.228109721024087	0.862860063636893
GO:0001530	lipopolysaccharide binding	7/2277	41/18639	0.170731707317073	1.39757061602237	0.228922057699584	0.862860063636893
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	7/2277	41/18639	0.170731707317073	1.39757061602237	0.228922057699584	0.862860063636893
GO:0017080	sodium channel regulator activity	7/2277	41/18639	0.170731707317073	1.39757061602237	0.228922057699584	0.862860063636893
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	18/2277	122/18639	0.147540983606557	1.20773666817858	0.230586724162723	0.865662837868771
GO:0097110	scaffold protein binding	11/2277	70/18639	0.157142857142857	1.28633540372671	0.231024619211446	0.865662837868771
GO:0005161	platelet-derived growth factor receptor binding	3/2277	14/18639	0.214285714285714	1.7540937323546	0.239850908756131	0.873057307872317
GO:0005347	ATP transmembrane transporter activity	3/2277	14/18639	0.214285714285714	1.7540937323546	0.239850908756131	0.873057307872317
GO:0008474	palmitoyl-(protein) hydrolase activity	3/2277	14/18639	0.214285714285714	1.7540937323546	0.239850908756131	0.873057307872317
GO:0008559	ABC-type xenobiotic transporter activity	3/2277	14/18639	0.214285714285714	1.7540937323546	0.239850908756131	0.873057307872317
GO:0016530	metallochaperone activity	3/2277	14/18639	0.214285714285714	1.7540937323546	0.239850908756131	0.873057307872317
GO:0030983	mismatched DNA binding	3/2277	14/18639	0.214285714285714	1.7540937323546	0.239850908756131	0.873057307872317
GO:0034236	protein kinase A catalytic subunit binding	3/2277	14/18639	0.214285714285714	1.7540937323546	0.239850908756131	0.873057307872317
GO:0061665	SUMO ligase activity	3/2277	14/18639	0.214285714285714	1.7540937323546	0.239850908756131	0.873057307872317
GO:0071933	Arp2/3 complex binding	3/2277	14/18639	0.214285714285714	1.7540937323546	0.239850908756131	0.873057307872317
GO:0098599	palmitoyl hydrolase activity	3/2277	14/18639	0.214285714285714	1.7540937323546	0.239850908756131	0.873057307872317
GO:0000287	magnesium ion binding	32/2277	230/18639	0.139130434782609	1.13888984361574	0.2411958591346	0.875451636858919
GO:0043021	ribonucleoprotein complex binding	25/2277	177/18639	0.141242937853107	1.1561823094616	0.248410678441881	0.896246957757829
GO:0005248	voltage-gated sodium channel activity	4/2277	21/18639	0.19047619047619	1.55919442875965	0.249739144430164	0.896246957757829
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	4/2277	21/18639	0.19047619047619	1.55919442875965	0.249739144430164	0.896246957757829
GO:0051010	microtubule plus-end binding	4/2277	21/18639	0.19047619047619	1.55919442875965	0.249739144430164	0.896246957757829
GO:0140566	histone reader activity	6/2277	35/18639	0.171428571428571	1.40327498588368	0.250841603412197	0.896676440834919
GO:0051537	2 iron, 2 sulfur cluster binding	5/2277	28/18639	0.178571428571429	1.46174477696217	0.251970302840582	0.896676440834919
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	5/2277	28/18639	0.178571428571429	1.46174477696217	0.251970302840582	0.896676440834919
GO:0042393	histone binding	34/2277	247/18639	0.137651821862348	1.12678625722104	0.253242698067314	0.898694143002113
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	19/2277	132/18639	0.143939393939394	1.17825488082405	0.256826542296339	0.908880596904267
GO:0008081	phosphoric diester hydrolase activity	13/2277	87/18639	0.149425287356322	1.22316114669938	0.261180822518374	0.921729550937419
GO:0015605	organophosphate ester transmembrane transporter activity	8/2277	50/18639	0.16	1.3097233201581	0.262230306831154	0.922876825698592
GO:0140104	molecular carrier activity	34/2277	249/18639	0.136546184738956	1.11773576519517	0.269104286561299	0.936557081538806
GO:0005484	SNAP receptor activity	6/2277	36/18639	0.166666666666667	1.36429512516469	0.272504644247077	0.936557081538806
GO:0017116	single-stranded DNA helicase activity	9/2277	58/18639	0.155172413793103	1.27020580618782	0.273583249781751	0.936557081538806
GO:0000774	adenyl-nucleotide exchange factor activity	3/2277	15/18639	0.2	1.63715415019763	0.274600567471566	0.936557081538806
GO:0004953	icosanoid receptor activity	3/2277	15/18639	0.2	1.63715415019763	0.274600567471566	0.936557081538806
GO:0005041	low-density lipoprotein particle receptor activity	3/2277	15/18639	0.2	1.63715415019763	0.274600567471566	0.936557081538806
GO:0016846	carbon-sulfur lyase activity	3/2277	15/18639	0.2	1.63715415019763	0.274600567471566	0.936557081538806
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	3/2277	15/18639	0.2	1.63715415019763	0.274600567471566	0.936557081538806
GO:0141050	histone H3K deacetylase activity	3/2277	15/18639	0.2	1.63715415019763	0.274600567471566	0.936557081538806
GO:0141051	histone H4K deacetylase activity	3/2277	15/18639	0.2	1.63715415019763	0.274600567471566	0.936557081538806
GO:0043539	protein serine/threonine kinase activator activity	11/2277	73/18639	0.150684931506849	1.23347230494342	0.275316576238042	0.936557081538806
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	5/2277	29/18639	0.172413793103448	1.41133978465313	0.276409311348972	0.936557081538806
GO:0097472	cyclin-dependent protein kinase activity	5/2277	29/18639	0.172413793103448	1.41133978465313	0.276409311348972	0.936557081538806
GO:0106222	lncRNA binding	5/2277	29/18639	0.172413793103448	1.41133978465313	0.276409311348972	0.936557081538806
GO:1902936	phosphatidylinositol bisphosphate binding	16/2277	111/18639	0.144144144144144	1.17993091906135	0.278108774754172	0.937414298948881
GO:0140035	ubiquitin-like protein reader activity	4/2277	22/18639	0.181818181818182	1.48832195472512	0.278133912874943	0.937414298948881
GO:0008235	metalloexopeptidase activity	10/2277	66/18639	0.151515151515152	1.24026829560426	0.282880543662205	0.950896603233903
GO:0140030	modification-dependent protein binding	24/2277	173/18639	0.138728323699422	1.13559825447234	0.283751506822577	0.95131426234727
GO:0016790	thiolester hydrolase activity	7/2277	44/18639	0.159090909090909	1.30228171038448	0.287567338666344	0.961576875225519
GO:0003678	DNA helicase activity	11/2277	74/18639	0.148648648648649	1.21680376028202	0.290639366844062	0.964906287745189
GO:0031593	polyubiquitin modification-dependent protein binding	9/2277	59/18639	0.152542372881356	1.24867689421853	0.29081045640469	0.964906287745189
GO:0016887	ATP hydrolysis activity	55/2277	417/18639	0.13189448441247	1.07965801272026	0.290835176212051	0.964906287745189
GO:0005158	insulin receptor binding	4/2277	23/18639	0.173913043478261	1.42361230451968	0.306997882987579	0.972552265125003
GO:0140102	catalytic activity, acting on a rRNA	4/2277	23/18639	0.173913043478261	1.42361230451968	0.306997882987579	0.972552265125003
GO:0008170	N-methyltransferase activity	14/2277	98/18639	0.142857142857143	1.16939582156973	0.307738542285091	0.972552265125003
GO:0008009	chemokine activity	7/2277	45/18639	0.155555555555556	1.27334211682038	0.307865447864223	0.972552265125003
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	3/2277	16/18639	0.1875	1.53483201581028	0.309800614557049	0.972552265125003
GO:0034450	ubiquitin-ubiquitin ligase activity	3/2277	16/18639	0.1875	1.53483201581028	0.309800614557049	0.972552265125003
GO:0070411	I-SMAD binding	3/2277	16/18639	0.1875	1.53483201581028	0.309800614557049	0.972552265125003
GO:0097027	ubiquitin-protein transferase activator activity	3/2277	16/18639	0.1875	1.53483201581028	0.309800614557049	0.972552265125003
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	3/2277	16/18639	0.1875	1.53483201581028	0.309800614557049	0.972552265125003
GO:0000149	SNARE binding	15/2277	106/18639	0.141509433962264	1.15836378551719	0.31201043402898	0.972552265125003
GO:0001540	amyloid-beta binding	12/2277	83/18639	0.144578313253012	1.18348492785371	0.312093414632839	0.972552265125003
GO:0008135	translation factor activity, RNA binding	12/2277	83/18639	0.144578313253012	1.18348492785371	0.312093414632839	0.972552265125003
GO:0016741	transferase activity, transferring one-carbon groups	29/2277	215/18639	0.134883720930233	1.10412721757514	0.312736623222856	0.972552265125003
GO:0032934	sterol binding	10/2277	68/18639	0.147058823529412	1.20378981632179	0.315767576142023	0.972552265125003
GO:0042162	telomeric DNA binding	6/2277	38/18639	0.157894736842105	1.29249011857708	0.317009892417801	0.972552265125003
GO:0043531	ADP binding	6/2277	38/18639	0.157894736842105	1.29249011857708	0.317009892417801	0.972552265125003
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	13/2277	91/18639	0.142857142857143	1.16939582156973	0.317138024983022	0.972552265125003
GO:1901505	carbohydrate derivative transmembrane transporter activity	8/2277	53/18639	0.150943396226415	1.235588037885	0.318013852526737	0.972552265125003
GO:0005178	integrin binding	22/2277	161/18639	0.136645962732919	1.11855252497975	0.320395219277689	0.972552265125003
GO:0017022	myosin binding	11/2277	76/18639	0.144736842105263	1.18478260869565	0.321950587955324	0.972552265125003
GO:0016798	hydrolase activity, acting on glycosyl bonds	18/2277	130/18639	0.138461538461538	1.13341441167528	0.322076463180657	0.972552265125003
GO:0019888	protein phosphatase regulator activity	15/2277	107/18639	0.14018691588785	1.147537955746	0.325293384317621	0.972552265125003
GO:0015026	coreceptor activity	9/2277	61/18639	0.147540983606557	1.20773666817858	0.326031346145422	0.972552265125003
GO:0016836	hydro-lyase activity	9/2277	61/18639	0.147540983606557	1.20773666817858	0.326031346145422	0.972552265125003
GO:0019905	syntaxin binding	9/2277	61/18639	0.147540983606557	1.20773666817858	0.326031346145422	0.972552265125003
GO:0072349	modified amino acid transmembrane transporter activity	5/2277	31/18639	0.161290322580645	1.32028560499809	0.326508615405664	0.972552265125003
GO:0180051	translation factor activity	12/2277	84/18639	0.142857142857143	1.16939582156973	0.327153403343148	0.972552265125003
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	7/2277	46/18639	0.152173913043478	1.24566076645472	0.328427064176319	0.972552265125003
GO:0030276	clathrin binding	7/2277	46/18639	0.152173913043478	1.24566076645472	0.328427064176319	0.972552265125003
GO:0001221	transcription coregulator binding	16/2277	115/18639	0.139130434782609	1.13888984361574	0.328626335820004	0.972552265125003
GO:0002039	p53 binding	10/2277	69/18639	0.144927536231884	1.18634358709973	0.332522952860902	0.972552265125003
GO:0043130	ubiquitin binding	14/2277	100/18639	0.14	1.14600790513834	0.335400069193711	0.972552265125003
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	4/2277	24/18639	0.166666666666667	1.36429512516469	0.336138538503449	0.972552265125003
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	4/2277	24/18639	0.166666666666667	1.36429512516469	0.336138538503449	0.972552265125003
GO:0140612	DNA damage sensor activity	4/2277	24/18639	0.166666666666667	1.36429512516469	0.336138538503449	0.972552265125003
GO:0140463	chromatin-protein adaptor activity	8/2277	54/18639	0.148148148148148	1.21270677792417	0.337112924580453	0.972552265125003
GO:0005496	steroid binding	15/2277	108/18639	0.138888888888889	1.13691260430391	0.338710545524387	0.972552265125003
GO:0008094	ATP-dependent activity, acting on DNA	28/2277	210/18639	0.133333333333333	1.09143610013175	0.339776136997395	0.972552265125003
GO:0004386	helicase activity	21/2277	155/18639	0.135483870967742	1.10903990819839	0.34047746736793	0.972552265125003
GO:0106310	protein serine kinase activity	47/2277	361/18639	0.130193905817175	1.06573746619513	0.342399535402475	0.972552265125003
GO:0015179	L-amino acid transmembrane transporter activity	9/2277	62/18639	0.145161290322581	1.18825704449828	0.343940428311143	0.972552265125003
GO:0004029	aldehyde dehydrogenase (NAD+) activity	3/2277	17/18639	0.176470588235294	1.44454777958614	0.345117040162902	0.972552265125003
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	3/2277	17/18639	0.176470588235294	1.44454777958614	0.345117040162902	0.972552265125003
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	3/2277	17/18639	0.176470588235294	1.44454777958614	0.345117040162902	0.972552265125003
GO:0048038	quinone binding	3/2277	17/18639	0.176470588235294	1.44454777958614	0.345117040162902	0.972552265125003
GO:0141003	histone H2AX kinase activity	46/2277	354/18639	0.129943502824859	1.06368772470467	0.349593860262452	0.972552265125003
GO:0004445	inositol-polyphosphate 5-phosphatase activity	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:0005131	growth hormone receptor binding	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:0005337	nucleoside transmembrane transporter activity	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:0005528	FK506 binding	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:0015658	branched-chain amino acid transmembrane transporter activity	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:0016175	superoxide-generating NAD(P)H oxidase activity	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:0031434	mitogen-activated protein kinase kinase binding	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:0032356	oxidized DNA binding	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:0042975	peroxisome proliferator activated receptor binding	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:0043295	glutathione binding	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:0045322	unmethylated CpG binding	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:0050815	phosphoserine residue binding	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:0051880	G-quadruplex DNA binding	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:0070097	delta-catenin binding	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:0070513	death domain binding	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:0070739	protein-glutamic acid ligase activity	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:0070740	tubulin-glutamic acid ligase activity	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:1905394	retromer complex binding	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:1990763	arrestin family protein binding	2/2277	10/18639	0.2	1.63715415019763	0.35012991711942	0.972552265125003
GO:0030515	snoRNA binding	5/2277	32/18639	0.15625	1.2790266798419	0.351920403628435	0.972552265125003
GO:0043425	bHLH transcription factor binding	5/2277	32/18639	0.15625	1.2790266798419	0.351920403628435	0.972552265125003
GO:0070717	poly-purine tract binding	5/2277	32/18639	0.15625	1.2790266798419	0.351920403628435	0.972552265125003
GO:0140142	nucleocytoplasmic carrier activity	5/2277	32/18639	0.15625	1.2790266798419	0.351920403628435	0.972552265125003
GO:0008201	heparin binding	23/2277	172/18639	0.133720930232558	1.0946088794926	0.354465323576432	0.977464983195614
GO:0140313	molecular sequestering activity	8/2277	55/18639	0.145454545454545	1.19065756378009	0.356377493719297	0.980615393085064
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	12/2277	86/18639	0.13953488372093	1.14220056990532	0.357709442234108	0.982159115099685
GO:0005507	copper ion binding	9/2277	63/18639	0.142857142857143	1.16939582156973	0.361992332103493	0.991781142150215
GO:0017056	structural constituent of nuclear pore	4/2277	25/18639	0.16	1.3097233201581	0.365375580363108	0.994633524321794
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	4/2277	25/18639	0.16	1.3097233201581	0.365375580363108	0.994633524321794
GO:0120020	cholesterol transfer activity	4/2277	25/18639	0.16	1.3097233201581	0.365375580363108	0.994633524321794
GO:0140311	protein sequestering activity	5/2277	33/18639	0.151515151515152	1.24026829560426	0.377416280640557	0.995932189243206
GO:0000900	mRNA regulatory element binding translation repressor activity	3/2277	18/18639	0.166666666666667	1.36429512516469	0.380254690034652	0.995932189243206
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	3/2277	18/18639	0.166666666666667	1.36429512516469	0.380254690034652	0.995932189243206
GO:0008409	5'-3' exonuclease activity	3/2277	18/18639	0.166666666666667	1.36429512516469	0.380254690034652	0.995932189243206
GO:0015172	acidic amino acid transmembrane transporter activity	3/2277	18/18639	0.166666666666667	1.36429512516469	0.380254690034652	0.995932189243206
GO:0030228	lipoprotein particle receptor activity	3/2277	18/18639	0.166666666666667	1.36429512516469	0.380254690034652	0.995932189243206
GO:0031690	adrenergic receptor binding	3/2277	18/18639	0.166666666666667	1.36429512516469	0.380254690034652	0.995932189243206
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	3/2277	18/18639	0.166666666666667	1.36429512516469	0.380254690034652	0.995932189243206
GO:0098641	cadherin binding involved in cell-cell adhesion	3/2277	18/18639	0.166666666666667	1.36429512516469	0.380254690034652	0.995932189243206
GO:1901611	phosphatidylglycerol binding	3/2277	18/18639	0.166666666666667	1.36429512516469	0.380254690034652	0.995932189243206
GO:0001727	lipid kinase activity	6/2277	41/18639	0.146341463414634	1.19791767087631	0.385395749426802	0.995932189243206
GO:0015175	neutral L-amino acid transmembrane transporter activity	6/2277	41/18639	0.146341463414634	1.19791767087631	0.385395749426802	0.995932189243206
GO:0000049	tRNA binding	11/2277	80/18639	0.1375	1.12554347826087	0.38640451226005	0.995932189243206
GO:0048306	calcium-dependent protein binding	11/2277	80/18639	0.1375	1.12554347826087	0.38640451226005	0.995932189243206
GO:0032182	ubiquitin-like protein binding	16/2277	120/18639	0.133333333333333	1.09143610013175	0.394436083934196	0.995932189243206
GO:0004112	cyclic-nucleotide phosphodiesterase activity	4/2277	26/18639	0.153846153846154	1.25934934630587	0.394542440413991	0.995932189243206
GO:0004435	phosphatidylinositol phospholipase C activity	4/2277	26/18639	0.153846153846154	1.25934934630587	0.394542440413991	0.995932189243206
GO:0005160	transforming growth factor beta receptor binding	4/2277	26/18639	0.153846153846154	1.25934934630587	0.394542440413991	0.995932189243206
GO:0008157	protein phosphatase 1 binding	4/2277	26/18639	0.153846153846154	1.25934934630587	0.394542440413991	0.995932189243206
GO:0030247	polysaccharide binding	4/2277	26/18639	0.153846153846154	1.25934934630587	0.394542440413991	0.995932189243206
GO:0052742	phosphatidylinositol kinase activity	4/2277	26/18639	0.153846153846154	1.25934934630587	0.394542440413991	0.995932189243206
GO:0000099	sulfur amino acid transmembrane transporter activity	2/2277	11/18639	0.181818181818182	1.48832195472512	0.396340361025357	0.995932189243206
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	2/2277	11/18639	0.181818181818182	1.48832195472512	0.396340361025357	0.995932189243206
GO:0004143	ATP-dependent diacylglycerol kinase activity	2/2277	11/18639	0.181818181818182	1.48832195472512	0.396340361025357	0.995932189243206
GO:0005536	D-glucose binding	2/2277	11/18639	0.181818181818182	1.48832195472512	0.396340361025357	0.995932189243206
GO:0008503	benzodiazepine receptor activity	2/2277	11/18639	0.181818181818182	1.48832195472512	0.396340361025357	0.995932189243206
GO:0010854	adenylate cyclase regulator activity	2/2277	11/18639	0.181818181818182	1.48832195472512	0.396340361025357	0.995932189243206
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	2/2277	11/18639	0.181818181818182	1.48832195472512	0.396340361025357	0.995932189243206
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/2277	11/18639	0.181818181818182	1.48832195472512	0.396340361025357	0.995932189243206
GO:0019107	myristoyltransferase activity	2/2277	11/18639	0.181818181818182	1.48832195472512	0.396340361025357	0.995932189243206
GO:0019206	nucleoside kinase activity	2/2277	11/18639	0.181818181818182	1.48832195472512	0.396340361025357	0.995932189243206
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	2/2277	11/18639	0.181818181818182	1.48832195472512	0.396340361025357	0.995932189243206
GO:0034056	estrogen response element binding	2/2277	11/18639	0.181818181818182	1.48832195472512	0.396340361025357	0.995932189243206
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	2/2277	11/18639	0.181818181818182	1.48832195472512	0.396340361025357	0.995932189243206
GO:0048185	activin binding	2/2277	11/18639	0.181818181818182	1.48832195472512	0.396340361025357	0.995932189243206
GO:0050998	nitric-oxide synthase binding	2/2277	11/18639	0.181818181818182	1.48832195472512	0.396340361025357	0.995932189243206
GO:0070697	activin receptor binding	2/2277	11/18639	0.181818181818182	1.48832195472512	0.396340361025357	0.995932189243206
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	2/2277	11/18639	0.181818181818182	1.48832195472512	0.396340361025357	0.995932189243206
GO:1900750	oligopeptide binding	2/2277	11/18639	0.181818181818182	1.48832195472512	0.396340361025357	0.995932189243206
GO:0160215	deacylase activity	9/2277	65/18639	0.138461538461538	1.13341441167528	0.398358585344641	0.997706365301881
GO:0016829	lyase activity	26/2277	200/18639	0.13	1.06415019762846	0.398612668711662	0.997706365301881
GO:0015020	glucuronosyltransferase activity	5/2277	34/18639	0.147058823529412	1.20378981632179	0.402886074624009	0.999999999999966
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	5/2277	34/18639	0.147058823529412	1.20378981632179	0.402886074624009	0.999999999999966
GO:0003697	single-stranded DNA binding	16/2277	121/18639	0.132231404958678	1.08241596707281	0.407794512264295	0.999999999999966
GO:0031492	nucleosomal DNA binding	6/2277	42/18639	0.142857142857143	1.16939582156973	0.408290200127866	0.999999999999966
GO:0042056	chemoattractant activity	6/2277	42/18639	0.142857142857143	1.16939582156973	0.408290200127866	0.999999999999966
GO:0043175	RNA polymerase core enzyme binding	6/2277	42/18639	0.142857142857143	1.16939582156973	0.408290200127866	0.999999999999966
GO:0003779	actin binding	56/2277	443/18639	0.126410835214447	1.0347701175064	0.413042452346841	0.999999999999966
GO:0003756	protein disulfide isomerase activity	3/2277	19/18639	0.157894736842105	1.29249011857708	0.414957152725173	0.999999999999966
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	3/2277	19/18639	0.157894736842105	1.29249011857708	0.414957152725173	0.999999999999966
GO:0005346	purine ribonucleotide transmembrane transporter activity	3/2277	19/18639	0.157894736842105	1.29249011857708	0.414957152725173	0.999999999999966
GO:0008301	DNA binding, bending	3/2277	19/18639	0.157894736842105	1.29249011857708	0.414957152725173	0.999999999999966
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	3/2277	19/18639	0.157894736842105	1.29249011857708	0.414957152725173	0.999999999999966
GO:0070003	threonine-type peptidase activity	3/2277	19/18639	0.157894736842105	1.29249011857708	0.414957152725173	0.999999999999966
GO:0008013	beta-catenin binding	14/2277	106/18639	0.132075471698113	1.08113953314938	0.420792103361449	0.999999999999966
GO:0008320	protein transmembrane transporter activity	4/2277	27/18639	0.148148148148148	1.21270677792417	0.423487261177453	0.999999999999966
GO:1901681	sulfur compound binding	35/2277	275/18639	0.127272727272727	1.04182536830758	0.42469099999956	0.999999999999966
GO:0000175	3'-5'-RNA exonuclease activity	5/2277	35/18639	0.142857142857143	1.16939582156973	0.428226819825977	0.999999999999966
GO:0043015	gamma-tubulin binding	5/2277	35/18639	0.142857142857143	1.16939582156973	0.428226819825977	0.999999999999966
GO:0004712	protein serine/threonine/tyrosine kinase activity	6/2277	43/18639	0.13953488372093	1.14220056990532	0.431104896613515	0.999999999999966
GO:0005021	vascular endothelial growth factor receptor activity	7/2277	51/18639	0.137254901960784	1.12353716190033	0.432924919671455	0.999999999999966
GO:0030544	Hsp70 protein binding	7/2277	51/18639	0.137254901960784	1.12353716190033	0.432924919671455	0.999999999999966
GO:0050840	extracellular matrix binding	9/2277	67/18639	0.134328358208955	1.09958114565512	0.434806648930512	0.999999999999966
GO:0019003	GDP binding	10/2277	75/18639	0.133333333333333	1.09143610013175	0.435222550356141	0.999999999999966
GO:0008168	methyltransferase activity	26/2277	204/18639	0.127450980392157	1.04328450747888	0.440191036184337	0.999999999999966
GO:0004032	aldose reductase (NADPH) activity	2/2277	12/18639	0.166666666666667	1.36429512516469	0.440963902367057	0.999999999999966
GO:0004526	ribonuclease P activity	2/2277	12/18639	0.166666666666667	1.36429512516469	0.440963902367057	0.999999999999966
GO:0005025	transforming growth factor beta receptor activity, type I	2/2277	12/18639	0.166666666666667	1.36429512516469	0.440963902367057	0.999999999999966
GO:0005026	transforming growth factor beta receptor activity, type II	2/2277	12/18639	0.166666666666667	1.36429512516469	0.440963902367057	0.999999999999966
GO:0005165	neurotrophin receptor binding	2/2277	12/18639	0.166666666666667	1.36429512516469	0.440963902367057	0.999999999999966
GO:0005527	macrolide binding	2/2277	12/18639	0.166666666666667	1.36429512516469	0.440963902367057	0.999999999999966
GO:0008504	monoamine transmembrane transporter activity	2/2277	12/18639	0.166666666666667	1.36429512516469	0.440963902367057	0.999999999999966
GO:0010853	cyclase activator activity	2/2277	12/18639	0.166666666666667	1.36429512516469	0.440963902367057	0.999999999999966
GO:0015132	prostaglandin transmembrane transporter activity	2/2277	12/18639	0.166666666666667	1.36429512516469	0.440963902367057	0.999999999999966
GO:0016361	activin receptor activity, type I	2/2277	12/18639	0.166666666666667	1.36429512516469	0.440963902367057	0.999999999999966
GO:0016362	activin receptor activity, type II	2/2277	12/18639	0.166666666666667	1.36429512516469	0.440963902367057	0.999999999999966
GO:0016801	hydrolase activity, acting on ether bonds	2/2277	12/18639	0.166666666666667	1.36429512516469	0.440963902367057	0.999999999999966
GO:0016803	ether hydrolase activity	2/2277	12/18639	0.166666666666667	1.36429512516469	0.440963902367057	0.999999999999966
GO:0017002	activin receptor activity	2/2277	12/18639	0.166666666666667	1.36429512516469	0.440963902367057	0.999999999999966
GO:0035251	UDP-glucosyltransferase activity	2/2277	12/18639	0.166666666666667	1.36429512516469	0.440963902367057	0.999999999999966
GO:0070410	co-SMAD binding	2/2277	12/18639	0.166666666666667	1.36429512516469	0.440963902367057	0.999999999999966
GO:0141221	histone deacetylase activity, hydrolytic mechanism	2/2277	12/18639	0.166666666666667	1.36429512516469	0.440963902367057	0.999999999999966
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	2/2277	12/18639	0.166666666666667	1.36429512516469	0.440963902367057	0.999999999999966
GO:0000339	RNA cap binding	3/2277	20/18639	0.15	1.22786561264822	0.449005559396196	0.999999999999966
GO:0001614	purinergic nucleotide receptor activity	3/2277	20/18639	0.15	1.22786561264822	0.449005559396196	0.999999999999966
GO:0016502	nucleotide receptor activity	3/2277	20/18639	0.15	1.22786561264822	0.449005559396196	0.999999999999966
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	3/2277	20/18639	0.15	1.22786561264822	0.449005559396196	0.999999999999966
GO:0042288	MHC class I protein binding	3/2277	20/18639	0.15	1.22786561264822	0.449005559396196	0.999999999999966
GO:0045499	chemorepellent activity	4/2277	28/18639	0.142857142857143	1.16939582156973	0.452073420900264	0.999999999999966
GO:0051959	dynein light intermediate chain binding	4/2277	28/18639	0.142857142857143	1.16939582156973	0.452073420900264	0.999999999999966
GO:0097718	disordered domain specific binding	4/2277	28/18639	0.142857142857143	1.16939582156973	0.452073420900264	0.999999999999966
GO:0098631	cell adhesion mediator activity	10/2277	76/18639	0.131578947368421	1.07707509881423	0.452384968901719	0.999999999999966
GO:0000993	RNA polymerase II complex binding	5/2277	36/18639	0.138888888888889	1.13691260430391	0.453343299758058	0.999999999999966
GO:0045505	dynein intermediate chain binding	5/2277	36/18639	0.138888888888889	1.13691260430391	0.453343299758058	0.999999999999966
GO:0004714	transmembrane receptor protein tyrosine kinase activity	8/2277	60/18639	0.133333333333333	1.09143610013175	0.453435569925398	0.999999999999966
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	8/2277	60/18639	0.133333333333333	1.09143610013175	0.453435569925398	0.999999999999966
GO:0030547	signaling receptor inhibitor activity	6/2277	44/18639	0.136363636363636	1.11624146604384	0.453768721552542	0.999999999999966
GO:0004674	protein serine/threonine kinase activity	54/2277	433/18639	0.124711316397229	1.02085824608166	0.457286133368118	0.999999999999966
GO:0015631	tubulin binding	48/2277	385/18639	0.124675324675325	1.02056362609722	0.463204534111205	0.999999999999966
GO:0016279	protein-lysine N-methyltransferase activity	9/2277	69/18639	0.130434782608696	1.06770922838976	0.471031481364019	0.999999999999966
GO:0005516	calmodulin binding	26/2277	207/18639	0.1256038647343	1.0281644421531	0.471456072988405	0.999999999999966
GO:0005003	ephrin receptor activity	7/2277	53/18639	0.132075471698113	1.08113953314938	0.474390660099584	0.999999999999966
GO:0005005	transmembrane-ephrin receptor activity	7/2277	53/18639	0.132075471698113	1.08113953314938	0.474390660099584	0.999999999999966
GO:0008146	sulfotransferase activity	7/2277	53/18639	0.132075471698113	1.08113953314938	0.474390660099584	0.999999999999966
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	21/2277	167/18639	0.125748502994012	1.02934841778893	0.478890541301694	0.999999999999966
GO:0004629	phospholipase C activity	4/2277	29/18639	0.137931034482759	1.1290718277225	0.480179678428471	0.999999999999966
GO:0005416	amino acid:monoatomic cation symporter activity	4/2277	29/18639	0.137931034482759	1.1290718277225	0.480179678428471	0.999999999999966
GO:0001846	opsonin binding	3/2277	21/18639	0.142857142857143	1.16939582156973	0.482216628557202	0.999999999999966
GO:0008373	sialyltransferase activity	3/2277	21/18639	0.142857142857143	1.16939582156973	0.482216628557202	0.999999999999966
GO:0009975	cyclase activity	3/2277	21/18639	0.142857142857143	1.16939582156973	0.482216628557202	0.999999999999966
GO:0015174	basic amino acid transmembrane transporter activity	3/2277	21/18639	0.142857142857143	1.16939582156973	0.482216628557202	0.999999999999966
GO:0019200	carbohydrate kinase activity	3/2277	21/18639	0.142857142857143	1.16939582156973	0.482216628557202	0.999999999999966
GO:0061891	calcium ion sensor activity	3/2277	21/18639	0.142857142857143	1.16939582156973	0.482216628557202	0.999999999999966
GO:0005172	vascular endothelial growth factor receptor binding	2/2277	13/18639	0.153846153846154	1.25934934630587	0.483698592363659	0.999999999999966
GO:0005338	nucleotide-sugar transmembrane transporter activity	2/2277	13/18639	0.153846153846154	1.25934934630587	0.483698592363659	0.999999999999966
GO:0005542	folic acid binding	2/2277	13/18639	0.153846153846154	1.25934934630587	0.483698592363659	0.999999999999966
GO:0008035	high-density lipoprotein particle binding	2/2277	13/18639	0.153846153846154	1.25934934630587	0.483698592363659	0.999999999999966
GO:0008253	5'-nucleotidase activity	2/2277	13/18639	0.153846153846154	1.25934934630587	0.483698592363659	0.999999999999966
GO:0009982	pseudouridine synthase activity	2/2277	13/18639	0.153846153846154	1.25934934630587	0.483698592363659	0.999999999999966
GO:0017154	semaphorin receptor activity	2/2277	13/18639	0.153846153846154	1.25934934630587	0.483698592363659	0.999999999999966
GO:0031432	titin binding	2/2277	13/18639	0.153846153846154	1.25934934630587	0.483698592363659	0.999999999999966
GO:0046975	histone H3K36 methyltransferase activity	2/2277	13/18639	0.153846153846154	1.25934934630587	0.483698592363659	0.999999999999966
GO:0051011	microtubule minus-end binding	2/2277	13/18639	0.153846153846154	1.25934934630587	0.483698592363659	0.999999999999966
GO:0070123	transforming growth factor beta receptor activity, type III	2/2277	13/18639	0.153846153846154	1.25934934630587	0.483698592363659	0.999999999999966
GO:0071714	icosanoid transmembrane transporter activity	2/2277	13/18639	0.153846153846154	1.25934934630587	0.483698592363659	0.999999999999966
GO:0140666	annealing activity	2/2277	13/18639	0.153846153846154	1.25934934630587	0.483698592363659	0.999999999999966
GO:0019199	transmembrane receptor protein kinase activity	10/2277	78/18639	0.128205128205128	1.04945778858822	0.486464040795566	0.999999999999966
GO:0016278	lysine N-methyltransferase activity	9/2277	70/18639	0.128571428571429	1.05245623941276	0.488971305233754	0.999999999999966
GO:0015485	cholesterol binding	7/2277	54/18639	0.12962962962963	1.06111843068365	0.494836280283284	0.999999999999966
GO:0017069	snRNA binding	7/2277	54/18639	0.12962962962963	1.06111843068365	0.494836280283284	0.999999999999966
GO:0005539	glycosaminoglycan binding	30/2277	242/18639	0.12396694214876	1.01476496913076	0.495288610636564	0.999999999999966
GO:0030291	protein serine/threonine kinase inhibitor activity	6/2277	46/18639	0.130434782608696	1.06770922838976	0.498383626273062	0.999999999999966
GO:0002020	protease binding	17/2277	136/18639	0.125	1.02322134387352	0.498848417606215	0.999999999999966
GO:0000146	microfilament motor activity	5/2277	38/18639	0.131578947368421	1.07707509881423	0.502563332088223	0.999999999999966
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	5/2277	38/18639	0.131578947368421	1.07707509881423	0.502563332088223	0.999999999999966
GO:0016835	carbon-oxygen lyase activity	10/2277	79/18639	0.126582278481013	1.03617351278331	0.503323102184859	0.999999999999966
GO:0001968	fibronectin binding	4/2277	30/18639	0.133333333333333	1.09143610013175	0.507700006514924	0.999999999999966
GO:0048019	receptor antagonist activity	4/2277	30/18639	0.133333333333333	1.09143610013175	0.507700006514924	0.999999999999966
GO:1901682	sulfur compound transmembrane transporter activity	8/2277	63/18639	0.126984126984127	1.03946295250643	0.51060884850139	0.999999999999966
GO:0004407	histone deacetylase activity	3/2277	22/18639	0.136363636363636	1.11624146604384	0.514440215243875	0.999999999999966
GO:0008093	cytoskeletal anchor activity	3/2277	22/18639	0.136363636363636	1.11624146604384	0.514440215243875	0.999999999999966
GO:0008649	rRNA methyltransferase activity	3/2277	22/18639	0.136363636363636	1.11624146604384	0.514440215243875	0.999999999999966
GO:0030021	extracellular matrix structural constituent conferring compression resistance	3/2277	22/18639	0.136363636363636	1.11624146604384	0.514440215243875	0.999999999999966
GO:0033558	protein lysine deacetylase activity	3/2277	22/18639	0.136363636363636	1.11624146604384	0.514440215243875	0.999999999999966
GO:0050321	tau-protein kinase activity	3/2277	22/18639	0.136363636363636	1.11624146604384	0.514440215243875	0.999999999999966
GO:0070034	telomerase RNA binding	3/2277	22/18639	0.136363636363636	1.11624146604384	0.514440215243875	0.999999999999966
GO:0140784	metal ion sensor activity	3/2277	22/18639	0.136363636363636	1.11624146604384	0.514440215243875	0.999999999999966
GO:0008374	O-acyltransferase activity	7/2277	55/18639	0.127272727272727	1.04182536830758	0.515028186657199	0.999999999999966
GO:0098632	cell-cell adhesion mediator activity	7/2277	55/18639	0.127272727272727	1.04182536830758	0.515028186657199	0.999999999999966
GO:0005504	fatty acid binding	6/2277	47/18639	0.127659574468085	1.04499201076444	0.520217421629114	0.999999999999966
GO:0043495	protein-membrane adaptor activity	6/2277	47/18639	0.127659574468085	1.04499201076444	0.520217421629114	0.999999999999966
GO:0140359	ABC-type transporter activity	6/2277	47/18639	0.127659574468085	1.04499201076444	0.520217421629114	0.999999999999966
GO:0140938	histone H3 methyltransferase activity	6/2277	47/18639	0.127659574468085	1.04499201076444	0.520217421629114	0.999999999999966
GO:0004705	JUN kinase activity	2/2277	14/18639	0.142857142857143	1.16939582156973	0.524339872964913	0.999999999999966
GO:0005313	L-glutamate transmembrane transporter activity	2/2277	14/18639	0.142857142857143	1.16939582156973	0.524339872964913	0.999999999999966
GO:0005545	1-phosphatidylinositol binding	2/2277	14/18639	0.142857142857143	1.16939582156973	0.524339872964913	0.999999999999966
GO:0008494	translation activator activity	2/2277	14/18639	0.142857142857143	1.16939582156973	0.524339872964913	0.999999999999966
GO:0019992	diacylglycerol binding	2/2277	14/18639	0.142857142857143	1.16939582156973	0.524339872964913	0.999999999999966
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	2/2277	14/18639	0.142857142857143	1.16939582156973	0.524339872964913	0.999999999999966
GO:0031404	chloride ion binding	2/2277	14/18639	0.142857142857143	1.16939582156973	0.524339872964913	0.999999999999966
GO:0070742	C2H2 zinc finger domain binding	2/2277	14/18639	0.142857142857143	1.16939582156973	0.524339872964913	0.999999999999966
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	2/2277	14/18639	0.142857142857143	1.16939582156973	0.524339872964913	0.999999999999966
GO:0098821	BMP receptor activity	2/2277	14/18639	0.142857142857143	1.16939582156973	0.524339872964913	0.999999999999966
GO:1901612	cardiolipin binding	2/2277	14/18639	0.142857142857143	1.16939582156973	0.524339872964913	0.999999999999966
GO:0000217	DNA secondary structure binding	5/2277	39/18639	0.128205128205128	1.04945778858822	0.526517627053218	0.999999999999966
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	5/2277	39/18639	0.128205128205128	1.04945778858822	0.526517627053218	0.999999999999966
GO:0003727	single-stranded RNA binding	11/2277	89/18639	0.123595505617978	1.01172447484123	0.531949457849218	0.999999999999966
GO:0016878	acid-thiol ligase activity	4/2277	31/18639	0.129032258064516	1.05622848399847	0.534543175568147	0.999999999999966
GO:0070851	growth factor receptor binding	17/2277	139/18639	0.122302158273381	1.00113742997697	0.536951023945707	0.999999999999966
GO:0140101	catalytic activity, acting on a tRNA	17/2277	139/18639	0.122302158273381	1.00113742997697	0.536951023945707	0.999999999999966
GO:0043177	organic acid binding	23/2277	189/18639	0.121693121693122	0.996151996151996	0.541444285144097	0.999999999999966
GO:0016879	ligase activity, forming carbon-nitrogen bonds	6/2277	48/18639	0.125	1.02322134387352	0.541665997281581	0.999999999999966
GO:0004521	RNA endonuclease activity	9/2277	73/18639	0.123287671232877	1.00920461313552	0.541715561099874	0.999999999999966
GO:0000295	adenine nucleotide transmembrane transporter activity	3/2277	23/18639	0.130434782608696	1.06770922838976	0.545556565082319	0.999999999999966
GO:0005283	amino acid:sodium symporter activity	3/2277	23/18639	0.130434782608696	1.06770922838976	0.545556565082319	0.999999999999966
GO:0008171	O-methyltransferase activity	3/2277	23/18639	0.130434782608696	1.06770922838976	0.545556565082319	0.999999999999966
GO:0043274	phospholipase binding	3/2277	23/18639	0.130434782608696	1.06770922838976	0.545556565082319	0.999999999999966
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	3/2277	23/18639	0.130434782608696	1.06770922838976	0.545556565082319	0.999999999999966
GO:0004532	RNA exonuclease activity	5/2277	40/18639	0.125	1.02322134387352	0.549949122290313	0.999999999999966
GO:0031369	translation initiation factor binding	4/2277	32/18639	0.125	1.02322134387352	0.560632142988106	0.999999999999966
GO:0042910	xenobiotic transmembrane transporter activity	4/2277	32/18639	0.125	1.02322134387352	0.560632142988106	0.999999999999966
GO:0051059	NF-kappaB binding	4/2277	32/18639	0.125	1.02322134387352	0.560632142988106	0.999999999999966
GO:0071813	lipoprotein particle binding	4/2277	32/18639	0.125	1.02322134387352	0.560632142988106	0.999999999999966
GO:0071814	protein-lipid complex binding	4/2277	32/18639	0.125	1.02322134387352	0.560632142988106	0.999999999999966
GO:0005004	GPI-linked ephrin receptor activity	6/2277	49/18639	0.122448979591837	1.0023392756312	0.56268386442049	0.999999999999966
GO:0005008	hepatocyte growth factor receptor activity	6/2277	49/18639	0.122448979591837	1.0023392756312	0.56268386442049	0.999999999999966
GO:0005009	insulin receptor activity	6/2277	49/18639	0.122448979591837	1.0023392756312	0.56268386442049	0.999999999999966
GO:0005011	macrophage colony-stimulating factor receptor activity	6/2277	49/18639	0.122448979591837	1.0023392756312	0.56268386442049	0.999999999999966
GO:0005018	platelet-derived growth factor alpha-receptor activity	6/2277	49/18639	0.122448979591837	1.0023392756312	0.56268386442049	0.999999999999966
GO:0005020	stem cell factor receptor activity	6/2277	49/18639	0.122448979591837	1.0023392756312	0.56268386442049	0.999999999999966
GO:0008288	boss receptor activity	6/2277	49/18639	0.122448979591837	1.0023392756312	0.56268386442049	0.999999999999966
GO:0016763	pentosyltransferase activity	6/2277	49/18639	0.122448979591837	1.0023392756312	0.56268386442049	0.999999999999966
GO:0035254	glutamate receptor binding	6/2277	49/18639	0.122448979591837	1.0023392756312	0.56268386442049	0.999999999999966
GO:0036332	placental growth factor receptor activity	6/2277	49/18639	0.122448979591837	1.0023392756312	0.56268386442049	0.999999999999966
GO:0038062	protein tyrosine kinase collagen receptor activity	6/2277	49/18639	0.122448979591837	1.0023392756312	0.56268386442049	0.999999999999966
GO:0060175	brain-derived neurotrophic factor receptor activity	6/2277	49/18639	0.122448979591837	1.0023392756312	0.56268386442049	0.999999999999966
GO:0008252	nucleotidase activity	2/2277	15/18639	0.133333333333333	1.09143610013175	0.562761304579274	0.999999999999966
GO:0010181	FMN binding	2/2277	15/18639	0.133333333333333	1.09143610013175	0.562761304579274	0.999999999999966
GO:0015556	C4-dicarboxylate transmembrane transporter activity	2/2277	15/18639	0.133333333333333	1.09143610013175	0.562761304579274	0.999999999999966
GO:0031005	filamin binding	2/2277	15/18639	0.133333333333333	1.09143610013175	0.562761304579274	0.999999999999966
GO:0034483	heparan sulfate sulfotransferase activity	2/2277	15/18639	0.133333333333333	1.09143610013175	0.562761304579274	0.999999999999966
GO:0042809	nuclear vitamin D receptor binding	2/2277	15/18639	0.133333333333333	1.09143610013175	0.562761304579274	0.999999999999966
GO:0048531	beta-1,3-galactosyltransferase activity	2/2277	15/18639	0.133333333333333	1.09143610013175	0.562761304579274	0.999999999999966
GO:0016877	ligase activity, forming carbon-sulfur bonds	5/2277	41/18639	0.121951219512195	0.998264725730261	0.572803757410245	0.999999999999966
GO:0140318	protein transporter activity	5/2277	41/18639	0.121951219512195	0.998264725730261	0.572803757410245	0.999999999999966
GO:0042625	ATPase-coupled ion transmembrane transporter activity	3/2277	24/18639	0.125	1.02322134387352	0.575473426022157	0.999999999999966
GO:0043998	histone H2A acetyltransferase activity	3/2277	24/18639	0.125	1.02322134387352	0.575473426022157	0.999999999999966
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	3/2277	24/18639	0.125	1.02322134387352	0.575473426022157	0.999999999999966
GO:0046961	proton-transporting ATPase activity, rotational mechanism	3/2277	24/18639	0.125	1.02322134387352	0.575473426022157	0.999999999999966
GO:0050431	transforming growth factor beta binding	3/2277	24/18639	0.125	1.02322134387352	0.575473426022157	0.999999999999966
GO:0060229	lipase activator activity	3/2277	24/18639	0.125	1.02322134387352	0.575473426022157	0.999999999999966
GO:0070300	phosphatidic acid binding	3/2277	24/18639	0.125	1.02322134387352	0.575473426022157	0.999999999999966
GO:0019001	guanyl nucleotide binding	48/2277	400/18639	0.12	0.982292490118577	0.576437083607543	0.999999999999966
GO:0032561	guanyl ribonucleotide binding	48/2277	400/18639	0.12	0.982292490118577	0.576437083607543	0.999999999999966
GO:0043178	alcohol binding	11/2277	92/18639	0.119565217391304	0.978733459357278	0.578175885089044	0.999999999999966
GO:0005006	epidermal growth factor receptor activity	6/2277	50/18639	0.12	0.982292490118577	0.583230759278617	0.999999999999966
GO:0005007	fibroblast growth factor receptor activity	6/2277	50/18639	0.12	0.982292490118577	0.583230759278617	0.999999999999966
GO:0005017	platelet-derived growth factor receptor activity	6/2277	50/18639	0.12	0.982292490118577	0.583230759278617	0.999999999999966
GO:0005019	platelet-derived growth factor beta-receptor activity	6/2277	50/18639	0.12	0.982292490118577	0.583230759278617	0.999999999999966
GO:0042054	histone methyltransferase activity	8/2277	67/18639	0.119402985074627	0.977405462804554	0.583435873620328	0.999999999999966
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	4/2277	33/18639	0.121212121212121	0.992214636483411	0.585903296415354	0.999999999999966
GO:0071889	14-3-3 protein binding	4/2277	33/18639	0.121212121212121	0.992214636483411	0.585903296415354	0.999999999999966
GO:0008307	structural constituent of muscle	5/2277	42/18639	0.119047619047619	0.974496517974779	0.595035319205161	0.999999999999966
GO:0000062	fatty-acyl-CoA binding	2/2277	16/18639	0.125	1.02322134387352	0.598898546011021	0.999999999999966
GO:0003688	DNA replication origin binding	2/2277	16/18639	0.125	1.02322134387352	0.598898546011021	0.999999999999966
GO:0005024	transforming growth factor beta receptor activity	2/2277	16/18639	0.125	1.02322134387352	0.598898546011021	0.999999999999966
GO:0005159	insulin-like growth factor receptor binding	2/2277	16/18639	0.125	1.02322134387352	0.598898546011021	0.999999999999966
GO:0005324	long-chain fatty acid transmembrane transporter activity	2/2277	16/18639	0.125	1.02322134387352	0.598898546011021	0.999999999999966
GO:0005521	lamin binding	2/2277	16/18639	0.125	1.02322134387352	0.598898546011021	0.999999999999966
GO:0008296	3'-5'-DNA exonuclease activity	2/2277	16/18639	0.125	1.02322134387352	0.598898546011021	0.999999999999966
GO:0022858	alanine transmembrane transporter activity	2/2277	16/18639	0.125	1.02322134387352	0.598898546011021	0.999999999999966
GO:0030275	LRR domain binding	2/2277	16/18639	0.125	1.02322134387352	0.598898546011021	0.999999999999966
GO:0031435	mitogen-activated protein kinase kinase kinase binding	2/2277	16/18639	0.125	1.02322134387352	0.598898546011021	0.999999999999966
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	2/2277	16/18639	0.125	1.02322134387352	0.598898546011021	0.999999999999966
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	2/2277	16/18639	0.125	1.02322134387352	0.598898546011021	0.999999999999966
GO:0003777	microtubule motor activity	8/2277	68/18639	0.117647058823529	0.963031853057429	0.600831969895136	0.999999999999966
GO:0015171	amino acid transmembrane transporter activity	12/2277	102/18639	0.117647058823529	0.963031853057429	0.600903990695471	0.999999999999966
GO:0005010	insulin-like growth factor receptor activity	6/2277	51/18639	0.117647058823529	0.963031853057429	0.603271537892904	0.999999999999966
GO:0005030	neurotrophin receptor activity	6/2277	51/18639	0.117647058823529	0.963031853057429	0.603271537892904	0.999999999999966
GO:0005048	signal sequence binding	6/2277	51/18639	0.117647058823529	0.963031853057429	0.603271537892904	0.999999999999966
GO:0005272	sodium channel activity	6/2277	51/18639	0.117647058823529	0.963031853057429	0.603271537892904	0.999999999999966
GO:0016779	nucleotidyltransferase activity	16/2277	136/18639	0.117647058823529	0.963031853057429	0.603453422684599	0.999999999999966
GO:0001848	complement binding	3/2277	25/18639	0.12	0.982292490118577	0.604123132248391	0.999999999999966
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	3/2277	25/18639	0.12	0.982292490118577	0.604123132248391	0.999999999999966
GO:0017025	TBP-class protein binding	3/2277	25/18639	0.12	0.982292490118577	0.604123132248391	0.999999999999966
GO:0019706	protein-cysteine S-palmitoyltransferase activity	3/2277	25/18639	0.12	0.982292490118577	0.604123132248391	0.999999999999966
GO:0019707	protein-cysteine S-acyltransferase activity	3/2277	25/18639	0.12	0.982292490118577	0.604123132248391	0.999999999999966
GO:0031406	carboxylic acid binding	22/2277	187/18639	0.117647058823529	0.963031853057429	0.608762400291914	0.999999999999966
GO:0008376	acetylgalactosaminyltransferase activity	4/2277	34/18639	0.117647058823529	0.963031853057429	0.6103055926542	0.999999999999966
GO:0090482	vitamin transmembrane transporter activity	4/2277	34/18639	0.117647058823529	0.963031853057429	0.6103055926542	0.999999999999966
GO:0008375	acetylglucosaminyltransferase activity	5/2277	43/18639	0.116279069767442	0.951833808254435	0.61660511165143	0.999999999999966
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	5/2277	43/18639	0.116279069767442	0.951833808254435	0.61660511165143	0.999999999999966
GO:0033218	amide binding	29/2277	247/18639	0.117408906882591	0.961082395865005	0.620093895798832	0.999999999999966
GO:0016758	hexosyltransferase activity	23/2277	197/18639	0.116751269035533	0.955699123211814	0.62486236490042	0.999999999999966
GO:0004540	RNA nuclease activity	14/2277	121/18639	0.115702479338843	0.947113971188711	0.627749408372044	0.999999999999966
GO:0004857	enzyme inhibitor activity	49/2277	416/18639	0.117788461538462	0.96418934326543	0.631225973406745	0.999999999999966
GO:0004529	DNA exonuclease activity	3/2277	26/18639	0.115384615384615	0.944512009729401	0.631459744226791	0.999999999999966
GO:0030507	spectrin binding	3/2277	26/18639	0.115384615384615	0.944512009729401	0.631459744226791	0.999999999999966
GO:0070412	R-SMAD binding	3/2277	26/18639	0.115384615384615	0.944512009729401	0.631459744226791	0.999999999999966
GO:0097602	cullin family protein binding	3/2277	26/18639	0.115384615384615	0.944512009729401	0.631459744226791	0.999999999999966
GO:0120014	phospholipid transfer activity	3/2277	26/18639	0.115384615384615	0.944512009729401	0.631459744226791	0.999999999999966
GO:0004549	tRNA-specific ribonuclease activity	2/2277	17/18639	0.117647058823529	0.963031853057429	0.632736080124104	0.999999999999966
GO:0005092	GDP-dissociation inhibitor activity	2/2277	17/18639	0.117647058823529	0.963031853057429	0.632736080124104	0.999999999999966
GO:0008569	minus-end-directed microtubule motor activity	2/2277	17/18639	0.117647058823529	0.963031853057429	0.632736080124104	0.999999999999966
GO:0017110	nucleoside diphosphate phosphatase activity	2/2277	17/18639	0.117647058823529	0.963031853057429	0.632736080124104	0.999999999999966
GO:0030548	acetylcholine receptor regulator activity	2/2277	17/18639	0.117647058823529	0.963031853057429	0.632736080124104	0.999999999999966
GO:0032183	SUMO binding	2/2277	17/18639	0.117647058823529	0.963031853057429	0.632736080124104	0.999999999999966
GO:0032977	membrane insertase activity	2/2277	17/18639	0.117647058823529	0.963031853057429	0.632736080124104	0.999999999999966
GO:0036041	long-chain fatty acid binding	2/2277	17/18639	0.117647058823529	0.963031853057429	0.632736080124104	0.999999999999966
GO:0038191	neuropilin binding	2/2277	17/18639	0.117647058823529	0.963031853057429	0.632736080124104	0.999999999999966
GO:0070403	NAD+ binding	2/2277	17/18639	0.117647058823529	0.963031853057429	0.632736080124104	0.999999999999966
GO:1901567	fatty acid derivative binding	2/2277	17/18639	0.117647058823529	0.963031853057429	0.632736080124104	0.999999999999966
GO:0010485	histone H4 acetyltransferase activity	4/2277	35/18639	0.114285714285714	0.935516657255788	0.633799627857841	0.999999999999966
GO:0016782	transferase activity, transferring sulphur-containing groups	8/2277	70/18639	0.114285714285714	0.935516657255788	0.634485136984555	0.999999999999966
GO:0043014	alpha-tubulin binding	5/2277	44/18639	0.113636363636364	0.930201221703198	0.637481571920519	0.999999999999966
GO:0030295	protein kinase activator activity	16/2277	139/18639	0.115107913669065	0.942246992919499	0.639350768934395	0.999999999999966
GO:0033293	monocarboxylic acid binding	9/2277	79/18639	0.113924050632911	0.932556161504978	0.640007974256189	0.999999999999966
GO:0034212	protein N-acetyltransferase activity	6/2277	53/18639	0.113207547169811	0.926691028413752	0.641718840079441	0.999999999999966
GO:0038064	collagen receptor activity	6/2277	53/18639	0.113207547169811	0.926691028413752	0.641718840079441	0.999999999999966
GO:0019209	kinase activator activity	17/2277	148/18639	0.114864864864865	0.940257451127016	0.644770041369629	0.999999999999966
GO:0016757	glycosyltransferase activity	31/2277	267/18639	0.116104868913858	0.950407840002369	0.647614228921096	0.999999999999966
GO:0004683	calcium/calmodulin-dependent protein kinase activity	3/2277	27/18639	0.111111111111111	0.909530083443127	0.657456304607958	0.999999999999966
GO:0008266	poly(U) RNA binding	3/2277	27/18639	0.111111111111111	0.909530083443127	0.657456304607958	0.999999999999966
GO:0016405	CoA-ligase activity	3/2277	27/18639	0.111111111111111	0.909530083443127	0.657456304607958	0.999999999999966
GO:0035255	ionotropic glutamate receptor binding	3/2277	27/18639	0.111111111111111	0.909530083443127	0.657456304607958	0.999999999999966
GO:0005525	GTP binding	44/2277	378/18639	0.116402116402116	0.952841039797562	0.658713981613911	0.999999999999966
GO:0140658	ATP-dependent chromatin remodeler activity	18/2277	158/18639	0.113924050632911	0.932556161504978	0.660772253604988	0.999999999999966
GO:0140098	catalytic activity, acting on RNA	45/2277	387/18639	0.116279069767442	0.951833808254435	0.662782740107984	0.999999999999966
GO:0042626	ATPase-coupled transmembrane transporter activity	11/2277	98/18639	0.112244897959184	0.918811002661934	0.664049963815297	0.999999999999966
GO:0003746	translation elongation factor activity	2/2277	18/18639	0.111111111111111	0.909530083443127	0.664296253885285	0.999999999999966
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	2/2277	18/18639	0.111111111111111	0.909530083443127	0.664296253885285	0.999999999999966
GO:0004970	glutamate-gated receptor activity	2/2277	18/18639	0.111111111111111	0.909530083443127	0.664296253885285	0.999999999999966
GO:0008525	phosphatidylcholine transporter activity	2/2277	18/18639	0.111111111111111	0.909530083443127	0.664296253885285	0.999999999999966
GO:0017075	syntaxin-1 binding	2/2277	18/18639	0.111111111111111	0.909530083443127	0.664296253885285	0.999999999999966
GO:0070628	proteasome binding	2/2277	18/18639	0.111111111111111	0.909530083443127	0.664296253885285	0.999999999999966
GO:0099602	neurotransmitter receptor regulator activity	2/2277	18/18639	0.111111111111111	0.909530083443127	0.664296253885285	0.999999999999966
GO:0008237	metallopeptidase activity	21/2277	184/18639	0.114130434782609	0.934245574841038	0.664447977913297	0.999999999999966
GO:0001618	virus receptor activity	9/2277	81/18639	0.111111111111111	0.909530083443127	0.670050763146894	0.999999999999966
GO:0042805	actinin binding	4/2277	37/18639	0.108108108108108	0.884948189296015	0.67795767045268	0.999999999999966
GO:0043394	proteoglycan binding	4/2277	37/18639	0.108108108108108	0.884948189296015	0.67795767045268	0.999999999999966
GO:0003689	DNA clamp loader activity	18/2277	160/18639	0.1125	0.920899209486166	0.681840130391912	0.999999999999966
GO:0036408	histone H3K14 acetyltransferase activity	3/2277	28/18639	0.107142857142857	0.877046866177301	0.682102250652882	0.999999999999966
GO:0140272	exogenous protein binding	9/2277	82/18639	0.109756097560976	0.898438253157235	0.68449863150942	0.999999999999966
GO:0072341	modified amino acid binding	10/2277	91/18639	0.10989010989011	0.899535247361334	0.687355164539003	0.999999999999966
GO:0035403	histone H3T6 kinase activity	28/2277	247/18639	0.11336032388664	0.927941623593798	0.693334648771881	0.999999999999966
GO:0004620	phospholipase activity	12/2277	109/18639	0.110091743119266	0.901185770750988	0.693412856753541	0.999999999999966
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	2/2277	19/18639	0.105263157894737	0.861660079051383	0.693630265786475	0.999999999999966
GO:0008381	mechanosensitive monoatomic ion channel activity	2/2277	19/18639	0.105263157894737	0.861660079051383	0.693630265786475	0.999999999999966
GO:0008574	plus-end-directed microtubule motor activity	2/2277	19/18639	0.105263157894737	0.861660079051383	0.693630265786475	0.999999999999966
GO:0015245	fatty acid transmembrane transporter activity	2/2277	19/18639	0.105263157894737	0.861660079051383	0.693630265786475	0.999999999999966
GO:0030506	ankyrin binding	2/2277	19/18639	0.105263157894737	0.861660079051383	0.693630265786475	0.999999999999966
GO:0042577	lipid phosphatase activity	2/2277	19/18639	0.105263157894737	0.861660079051383	0.693630265786475	0.999999999999966
GO:0042800	histone H3K4 methyltransferase activity	2/2277	19/18639	0.105263157894737	0.861660079051383	0.693630265786475	0.999999999999966
GO:0043395	heparan sulfate proteoglycan binding	2/2277	19/18639	0.105263157894737	0.861660079051383	0.693630265786475	0.999999999999966
GO:0046527	glucosyltransferase activity	2/2277	19/18639	0.105263157894737	0.861660079051383	0.693630265786475	0.999999999999966
GO:0046624	sphingolipid transporter activity	2/2277	19/18639	0.105263157894737	0.861660079051383	0.693630265786475	0.999999999999966
GO:0120227	acyl-CoA binding	2/2277	19/18639	0.105263157894737	0.861660079051383	0.693630265786475	0.999999999999966
GO:1990380	K48-linked deubiquitinase activity	2/2277	19/18639	0.105263157894737	0.861660079051383	0.693630265786475	0.999999999999966
GO:0019212	phosphatase inhibitor activity	6/2277	56/18639	0.107142857142857	0.877046866177301	0.69499046496094	0.999999999999966
GO:0120013	lipid transfer activity	7/2277	65/18639	0.107692307692308	0.881544542414108	0.695491784993892	0.999999999999966
GO:0061733	protein-lysine-acetyltransferase activity	5/2277	47/18639	0.106382978723404	0.870826675637036	0.695733230841556	0.999999999999966
GO:0035064	methylated histone binding	8/2277	74/18639	0.108108108108108	0.884948189296015	0.696769628806602	0.999999999999966
GO:0048029	monosaccharide binding	8/2277	74/18639	0.108108108108108	0.884948189296015	0.696769628806602	0.999999999999966
GO:0005109	frizzled binding	4/2277	38/18639	0.105263157894737	0.861660079051383	0.698592298495557	0.999999999999966
GO:0004181	metallocarboxypeptidase activity	3/2277	29/18639	0.103448275862069	0.846803870791877	0.705401008986468	0.999999999999966
GO:0010484	histone H3 acetyltransferase activity	3/2277	29/18639	0.103448275862069	0.846803870791877	0.705401008986468	0.999999999999966
GO:0016417	S-acyltransferase activity	3/2277	29/18639	0.103448275862069	0.846803870791877	0.705401008986468	0.999999999999966
GO:0004222	metalloendopeptidase activity	12/2277	110/18639	0.109090909090909	0.89299317283507	0.705512620493325	0.999999999999966
GO:0005326	neurotransmitter transmembrane transporter activity	2/2277	20/18639	0.1	0.818577075098814	0.720810788718727	0.999999999999966
GO:0010851	cyclase regulator activity	2/2277	20/18639	0.1	0.818577075098814	0.720810788718727	0.999999999999966
GO:0016004	phospholipase activator activity	2/2277	20/18639	0.1	0.818577075098814	0.720810788718727	0.999999999999966
GO:0016408	C-acyltransferase activity	2/2277	20/18639	0.1	0.818577075098814	0.720810788718727	0.999999999999966
GO:0030742	GTP-dependent protein binding	2/2277	20/18639	0.1	0.818577075098814	0.720810788718727	0.999999999999966
GO:0043024	ribosomal small subunit binding	2/2277	20/18639	0.1	0.818577075098814	0.720810788718727	0.999999999999966
GO:0140034	methylation-dependent protein binding	8/2277	76/18639	0.105263157894737	0.861660079051383	0.72522108224664	0.999999999999966
GO:0016500	protein-hormone receptor activity	7/2277	67/18639	0.104477611940299	0.855229779953985	0.725761996975281	0.999999999999966
GO:0008106	alcohol dehydrogenase (NADP+) activity	3/2277	30/18639	0.1	0.818577075098814	0.727367787038862	0.999999999999966
GO:0008187	poly-pyrimidine tract binding	3/2277	30/18639	0.1	0.818577075098814	0.727367787038862	0.999999999999966
GO:0031210	phosphatidylcholine binding	3/2277	30/18639	0.1	0.818577075098814	0.727367787038862	0.999999999999966
GO:0043995	histone H4K5 acetyltransferase activity	3/2277	30/18639	0.1	0.818577075098814	0.727367787038862	0.999999999999966
GO:0043996	histone H4K8 acetyltransferase activity	3/2277	30/18639	0.1	0.818577075098814	0.727367787038862	0.999999999999966
GO:0043997	histone H4K12 acetyltransferase activity	3/2277	30/18639	0.1	0.818577075098814	0.727367787038862	0.999999999999966
GO:0098918	structural constituent of synapse	3/2277	30/18639	0.1	0.818577075098814	0.727367787038862	0.999999999999966
GO:0000182	rDNA binding	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0001094	TFIID-class transcription factor complex binding	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0004090	carbonyl reductase (NADPH) activity	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0004935	adrenergic receptor activity	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0004955	prostaglandin receptor activity	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0005381	iron ion transmembrane transporter activity	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0008140	cAMP response element binding protein binding	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0008190	eukaryotic initiation factor 4E binding	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0008519	ammonium channel activity	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0008641	ubiquitin-like modifier activating enzyme activity	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0015187	glycine transmembrane transporter activity	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0015203	polyamine transmembrane transporter activity	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0015643	toxic substance binding	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0016427	tRNA (cytidine) methyltransferase activity	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0019911	structural constituent of myelin sheath	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0031419	cobalamin binding	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0032052	bile acid binding	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0033204	ribonuclease P RNA binding	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0035374	chondroitin sulfate binding	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0043208	glycosphingolipid binding	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0050308	sugar-phosphatase activity	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0051864	histone H3K36 demethylase activity	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0098505	G-rich strand telomeric DNA binding	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0099122	RNA polymerase II C-terminal domain binding	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0140940	histone H2A methyltransferase activity	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0140999	histone H3K4 trimethyltransferase activity	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0141109	transporter activator activity	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:1990259	histone H2AQ104 methyltransferase activity	1/2277	10/18639	0.1	0.818577075098814	0.728361182288011	0.999999999999966
GO:0005200	structural constituent of cytoskeleton	12/2277	112/18639	0.107142857142857	0.877046866177301	0.728810912988425	0.999999999999966
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	14/2277	130/18639	0.107692307692308	0.881544542414108	0.732276275843154	0.999999999999966
GO:0061134	peptidase regulator activity	25/2277	226/18639	0.110619469026549	0.905505614047361	0.732405951279459	0.999999999999966
GO:0004518	nuclease activity	23/2277	209/18639	0.110047846889952	0.900826446280992	0.735156792101626	0.999999999999966
GO:0001786	phosphatidylserine binding	6/2277	59/18639	0.101694915254237	0.832451262812353	0.74270347510068	0.999999999999966
GO:0070888	E-box binding	6/2277	59/18639	0.101694915254237	0.832451262812353	0.74270347510068	0.999999999999966
GO:0005123	death receptor binding	2/2277	21/18639	0.0952380952380952	0.779597214379823	0.745925963472573	0.999999999999966
GO:0015125	bile acid transmembrane transporter activity	2/2277	21/18639	0.0952380952380952	0.779597214379823	0.745925963472573	0.999999999999966
GO:0005310	dicarboxylic acid transmembrane transporter activity	3/2277	31/18639	0.0967741935483871	0.792171362998852	0.748027566839295	0.999999999999966
GO:0047499	calcium-independent phospholipase A2 activity	3/2277	31/18639	0.0967741935483871	0.792171362998852	0.748027566839295	0.999999999999966
GO:0016407	acetyltransferase activity	10/2277	96/18639	0.104166666666667	0.852684453227932	0.750282447570683	0.999999999999966
GO:0008080	N-acetyltransferase activity	7/2277	69/18639	0.101449275362319	0.830440510969812	0.753899886262744	0.999999999999966
GO:0001098	basal transcription machinery binding	6/2277	60/18639	0.1	0.818577075098814	0.757355879613811	0.999999999999966
GO:0001099	basal RNA polymerase II transcription machinery binding	6/2277	60/18639	0.1	0.818577075098814	0.757355879613811	0.999999999999966
GO:0035402	histone H3T11 kinase activity	27/2277	247/18639	0.109311740890688	0.89480085132259	0.760213665553356	0.999999999999966
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	1/2277	11/18639	0.0909090909090909	0.744160977362558	0.761563264414277	0.999999999999966
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	1/2277	11/18639	0.0909090909090909	0.744160977362558	0.761563264414277	0.999999999999966
GO:0001851	complement component C3b binding	1/2277	11/18639	0.0909090909090909	0.744160977362558	0.761563264414277	0.999999999999966
GO:0003953	NAD+ nucleosidase activity	1/2277	11/18639	0.0909090909090909	0.744160977362558	0.761563264414277	0.999999999999966
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/2277	11/18639	0.0909090909090909	0.744160977362558	0.761563264414277	0.999999999999966
GO:0004523	RNA-DNA hybrid ribonuclease activity	1/2277	11/18639	0.0909090909090909	0.744160977362558	0.761563264414277	0.999999999999966
GO:0004954	prostanoid receptor activity	1/2277	11/18639	0.0909090909090909	0.744160977362558	0.761563264414277	0.999999999999966
GO:0005114	type II transforming growth factor beta receptor binding	1/2277	11/18639	0.0909090909090909	0.744160977362558	0.761563264414277	0.999999999999966
GO:0008271	secondary active sulfate transmembrane transporter activity	1/2277	11/18639	0.0909090909090909	0.744160977362558	0.761563264414277	0.999999999999966
GO:0008432	JUN kinase binding	1/2277	11/18639	0.0909090909090909	0.744160977362558	0.761563264414277	0.999999999999966
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/2277	11/18639	0.0909090909090909	0.744160977362558	0.761563264414277	0.999999999999966
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/2277	11/18639	0.0909090909090909	0.744160977362558	0.761563264414277	0.999999999999966
GO:0019203	carbohydrate phosphatase activity	1/2277	11/18639	0.0909090909090909	0.744160977362558	0.761563264414277	0.999999999999966
GO:0032050	clathrin heavy chain binding	1/2277	11/18639	0.0909090909090909	0.744160977362558	0.761563264414277	0.999999999999966
GO:0034511	U3 snoRNA binding	1/2277	11/18639	0.0909090909090909	0.744160977362558	0.761563264414277	0.999999999999966
GO:0042608	T cell receptor binding	1/2277	11/18639	0.0909090909090909	0.744160977362558	0.761563264414277	0.999999999999966
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/2277	11/18639	0.0909090909090909	0.744160977362558	0.761563264414277	0.999999999999966
GO:0050786	RAGE receptor binding	1/2277	11/18639	0.0909090909090909	0.744160977362558	0.761563264414277	0.999999999999966
GO:0070990	snRNP binding	1/2277	11/18639	0.0909090909090909	0.744160977362558	0.761563264414277	0.999999999999966
GO:0097493	structural molecule activity conferring elasticity	1/2277	11/18639	0.0909090909090909	0.744160977362558	0.761563264414277	0.999999999999966
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/2277	11/18639	0.0909090909090909	0.744160977362558	0.761563264414277	0.999999999999966
GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/2277	11/18639	0.0909090909090909	0.744160977362558	0.761563264414277	0.999999999999966
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/2277	11/18639	0.0909090909090909	0.744160977362558	0.761563264414277	0.999999999999966
GO:0180030	inositol phosphate kinase activity	1/2277	11/18639	0.0909090909090909	0.744160977362558	0.761563264414277	0.999999999999966
GO:0016597	amino acid binding	5/2277	51/18639	0.0980392156862745	0.802526544214524	0.762844358402667	0.999999999999966
GO:0000510	H3-H4 histone complex chaperone activity	16/2277	151/18639	0.105960264900662	0.867366437190797	0.764498351809217	0.999999999999966
GO:0140584	chromatin extrusion motor activity	16/2277	151/18639	0.105960264900662	0.867366437190797	0.764498351809217	0.999999999999966
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	16/2277	151/18639	0.105960264900662	0.867366437190797	0.764498351809217	0.999999999999966
GO:0140849	ATP-dependent H2AZ histone chaperone activity	16/2277	151/18639	0.105960264900662	0.867366437190797	0.764498351809217	0.999999999999966
GO:0008378	galactosyltransferase activity	3/2277	32/18639	0.09375	0.767416007905138	0.767413300341143	0.999999999999966
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	3/2277	32/18639	0.09375	0.767416007905138	0.767413300341143	0.999999999999966
GO:0015377	chloride:monoatomic cation symporter activity	2/2277	22/18639	0.0909090909090909	0.744160977362558	0.769074538295442	0.999999999999966
GO:0016881	acid-amino acid ligase activity	2/2277	22/18639	0.0909090909090909	0.744160977362558	0.769074538295442	0.999999999999966
GO:0031683	G-protein beta/gamma-subunit complex binding	2/2277	22/18639	0.0909090909090909	0.744160977362558	0.769074538295442	0.999999999999966
GO:0032931	histone H3K56 acetyltransferase activity	2/2277	22/18639	0.0909090909090909	0.744160977362558	0.769074538295442	0.999999999999966
GO:0033691	sialic acid binding	2/2277	22/18639	0.0909090909090909	0.744160977362558	0.769074538295442	0.999999999999966
GO:0043992	histone H3K9 acetyltransferase activity	2/2277	22/18639	0.0909090909090909	0.744160977362558	0.769074538295442	0.999999999999966
GO:0043993	histone H3K18 acetyltransferase activity	2/2277	22/18639	0.0909090909090909	0.744160977362558	0.769074538295442	0.999999999999966
GO:0043994	histone H3K23 acetyltransferase activity	2/2277	22/18639	0.0909090909090909	0.744160977362558	0.769074538295442	0.999999999999966
GO:0043999	histone H2AK5 acetyltransferase activity	2/2277	22/18639	0.0909090909090909	0.744160977362558	0.769074538295442	0.999999999999966
GO:0044012	histone H2AK9 acetyltransferase activity	2/2277	22/18639	0.0909090909090909	0.744160977362558	0.769074538295442	0.999999999999966
GO:0044014	histone H2BK5 acetyltransferase activity	2/2277	22/18639	0.0909090909090909	0.744160977362558	0.769074538295442	0.999999999999966
GO:0044015	histone H2BK12 acetyltransferase activity	2/2277	22/18639	0.0909090909090909	0.744160977362558	0.769074538295442	0.999999999999966
GO:0044016	histone H3K4 acetyltransferase activity	2/2277	22/18639	0.0909090909090909	0.744160977362558	0.769074538295442	0.999999999999966
GO:0044017	histone H3K27 acetyltransferase activity	2/2277	22/18639	0.0909090909090909	0.744160977362558	0.769074538295442	0.999999999999966
GO:0044018	histone H3K36 acetyltransferase activity	2/2277	22/18639	0.0909090909090909	0.744160977362558	0.769074538295442	0.999999999999966
GO:0046972	histone H4K16 acetyltransferase activity	2/2277	22/18639	0.0909090909090909	0.744160977362558	0.769074538295442	0.999999999999966
GO:0140908	histone H3K122 acetyltransferase activity	2/2277	22/18639	0.0909090909090909	0.744160977362558	0.769074538295442	0.999999999999966
GO:0004402	histone acetyltransferase activity	4/2277	42/18639	0.0952380952380952	0.779597214379823	0.771512851155566	0.999999999999966
GO:0035198	miRNA binding	4/2277	42/18639	0.0952380952380952	0.779597214379823	0.771512851155566	0.999999999999966
GO:0015294	solute:monoatomic cation symporter activity	12/2277	116/18639	0.103448275862069	0.846803870791877	0.771716254627902	0.999999999999966
GO:0051087	protein-folding chaperone binding	14/2277	134/18639	0.104477611940299	0.855229779953985	0.772100607041261	0.999999999999966
GO:0015616	DNA translocase activity	16/2277	152/18639	0.105263157894737	0.861660079051383	0.773455444091363	0.999999999999966
GO:0140674	ATP-dependent histone chaperone activity	16/2277	152/18639	0.105263157894737	0.861660079051383	0.773455444091363	0.999999999999966
GO:0140097	catalytic activity, acting on DNA	37/2277	336/18639	0.110119047619048	0.90140927912667	0.775145512498771	0.999999999999966
GO:0008017	microtubule binding	30/2277	276/18639	0.108695652173913	0.889757690324798	0.779982887720405	0.999999999999966
GO:1990782	protein tyrosine kinase binding	12/2277	117/18639	0.102564102564103	0.839566230870579	0.781665547692886	0.999999999999966
GO:0003774	cytoskeletal motor activity	16/2277	153/18639	0.104575163398693	0.856028313828825	0.782177826031189	0.999999999999966
GO:0061775	cohesin loader activity	16/2277	153/18639	0.104575163398693	0.856028313828825	0.782177826031189	0.999999999999966
GO:0030296	protein tyrosine kinase activator activity	3/2277	33/18639	0.0909090909090909	0.744160977362558	0.785564300733722	0.999999999999966
GO:0005245	voltage-gated calcium channel activity	4/2277	43/18639	0.0930232558139535	0.761467046603548	0.787400824438041	0.999999999999966
GO:0015101	organic cation transmembrane transporter activity	8/2277	81/18639	0.0987654320987654	0.808471185282779	0.788218916990773	0.999999999999966
GO:0003887	DNA-directed DNA polymerase activity	2/2277	23/18639	0.0869565217391304	0.711806152259838	0.79036196431574	0.999999999999966
GO:0005212	structural constituent of eye lens	2/2277	23/18639	0.0869565217391304	0.711806152259838	0.79036196431574	0.999999999999966
GO:0016849	phosphorus-oxygen lyase activity	2/2277	23/18639	0.0869565217391304	0.711806152259838	0.79036196431574	0.999999999999966
GO:0044013	histone H2B acetyltransferase activity	2/2277	23/18639	0.0869565217391304	0.711806152259838	0.79036196431574	0.999999999999966
GO:0099186	structural constituent of postsynapse	2/2277	23/18639	0.0869565217391304	0.711806152259838	0.79036196431574	0.999999999999966
GO:0008194	UDP-glycosyltransferase activity	15/2277	145/18639	0.103448275862069	0.846803870791877	0.790421930900083	0.999999999999966
GO:0005506	iron ion binding	16/2277	154/18639	0.103896103896104	0.850469688414352	0.79066551000785	0.999999999999966
GO:0000340	RNA 7-methylguanosine cap binding	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0000995	RNA polymerase III general transcription initiation factor activity	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0003720	telomerase activity	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0003995	acyl-CoA dehydrogenase activity	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0004000	adenosine deaminase activity	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0004859	phospholipase inhibitor activity	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0005078	MAP-kinase scaffold activity	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0005095	GTPase inhibitor activity	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0005247	voltage-gated chloride channel activity	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0008603	cAMP-dependent protein kinase regulator activity	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0015166	polyol transmembrane transporter activity	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0016273	arginine N-methyltransferase activity	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0016274	protein-arginine N-methyltransferase activity	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0016423	tRNA (guanine) methyltransferase activity	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0017166	vinculin binding	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0031543	peptidyl-proline dioxygenase activity	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0035197	siRNA binding	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0035259	nuclear glucocorticoid receptor binding	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0036009	protein-glutamine N-methyltransferase activity	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0043047	single-stranded telomeric DNA binding	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0070679	inositol 1,4,5 trisphosphate binding	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:1990817	poly(A) RNA polymerase activity	1/2277	12/18639	0.0833333333333333	0.682147562582345	0.790708660964024	0.999999999999966
GO:0004864	protein phosphatase inhibitor activity	5/2277	53/18639	0.0943396226415094	0.772242523678127	0.791914661842831	0.999999999999966
GO:0140296	general transcription initiation factor binding	5/2277	53/18639	0.0943396226415094	0.772242523678127	0.791914661842831	0.999999999999966
GO:0042379	chemokine receptor binding	7/2277	72/18639	0.0972222222222222	0.795838823012736	0.792119268289834	0.999999999999966
GO:0003924	GTPase activity	36/2277	331/18639	0.108761329305136	0.890295308264571	0.796699213301635	0.999999999999966
GO:0001223	transcription coactivator binding	4/2277	44/18639	0.0909090909090909	0.744160977362558	0.802392749689793	0.999999999999966
GO:0016831	carboxy-lyase activity	3/2277	34/18639	0.0882352941176471	0.722273889793071	0.802524820870449	0.999999999999966
GO:0030332	cyclin binding	3/2277	34/18639	0.0882352941176471	0.722273889793071	0.802524820870449	0.999999999999966
GO:0030246	carbohydrate binding	30/2277	280/18639	0.107142857142857	0.877046866177301	0.805072209270951	0.999999999999966
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	5/2277	54/18639	0.0925925925925926	0.757941736202606	0.805367264066185	0.999999999999966
GO:0004676	3-phosphoinositide-dependent protein kinase activity	26/2277	245/18639	0.106122448979592	0.868694038880374	0.806325151063872	0.999999999999966
GO:0004711	ribosomal protein S6 kinase activity	26/2277	245/18639	0.106122448979592	0.868694038880374	0.806325151063872	0.999999999999966
GO:0035175	histone H3S10 kinase activity	26/2277	245/18639	0.106122448979592	0.868694038880374	0.806325151063872	0.999999999999966
GO:0035979	histone H2AXS139 kinase activity	26/2277	245/18639	0.106122448979592	0.868694038880374	0.806325151063872	0.999999999999966
GO:0044022	histone H3S28 kinase activity	26/2277	245/18639	0.106122448979592	0.868694038880374	0.806325151063872	0.999999999999966
GO:0044023	histone H4S1 kinase activity	26/2277	245/18639	0.106122448979592	0.868694038880374	0.806325151063872	0.999999999999966
GO:0044024	histone H2AS1 kinase activity	26/2277	245/18639	0.106122448979592	0.868694038880374	0.806325151063872	0.999999999999966
GO:0044025	histone H2BS14 kinase activity	26/2277	245/18639	0.106122448979592	0.868694038880374	0.806325151063872	0.999999999999966
GO:0072354	histone H3T3 kinase activity	26/2277	245/18639	0.106122448979592	0.868694038880374	0.806325151063872	0.999999999999966
GO:0072371	histone H2AS121 kinase activity	26/2277	245/18639	0.106122448979592	0.868694038880374	0.806325151063872	0.999999999999966
GO:0072518	Rho-dependent protein serine/threonine kinase activity	26/2277	245/18639	0.106122448979592	0.868694038880374	0.806325151063872	0.999999999999966
GO:0140823	histone H2BS36 kinase activity	26/2277	245/18639	0.106122448979592	0.868694038880374	0.806325151063872	0.999999999999966
GO:0140855	histone H3S57 kinase activity	26/2277	245/18639	0.106122448979592	0.868694038880374	0.806325151063872	0.999999999999966
GO:0140995	histone H2A kinase activity	26/2277	245/18639	0.106122448979592	0.868694038880374	0.806325151063872	0.999999999999966
GO:0140997	histone H4 kinase activity	26/2277	245/18639	0.106122448979592	0.868694038880374	0.806325151063872	0.999999999999966
GO:0140998	histone H2B kinase activity	26/2277	245/18639	0.106122448979592	0.868694038880374	0.806325151063872	0.999999999999966
GO:1990244	histone H2AT120 kinase activity	26/2277	245/18639	0.106122448979592	0.868694038880374	0.806325151063872	0.999999999999966
GO:0015149	hexose transmembrane transporter activity	2/2277	24/18639	0.0833333333333333	0.682147562582345	0.809897285978793	0.999999999999966
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	2/2277	24/18639	0.0833333333333333	0.682147562582345	0.809897285978793	0.999999999999966
GO:0030552	cAMP binding	2/2277	24/18639	0.0833333333333333	0.682147562582345	0.809897285978793	0.999999999999966
GO:0050699	WW domain binding	2/2277	24/18639	0.0833333333333333	0.682147562582345	0.809897285978793	0.999999999999966
GO:0055056	D-glucose transmembrane transporter activity	2/2277	24/18639	0.0833333333333333	0.682147562582345	0.809897285978793	0.999999999999966
GO:0004677	DNA-dependent protein kinase activity	26/2277	246/18639	0.105691056910569	0.86516276229956	0.812638677558704	0.999999999999966
GO:0140857	histone H3T45 kinase activity	26/2277	246/18639	0.105691056910569	0.86516276229956	0.812638677558704	0.999999999999966
GO:0003684	damaged DNA binding	7/2277	74/18639	0.0945945945945946	0.774329665634014	0.814997275580433	0.999999999999966
GO:0003964	RNA-directed DNA polymerase activity	1/2277	13/18639	0.0769230769230769	0.629674673152934	0.816292833347388	0.999999999999966
GO:0008417	fucosyltransferase activity	1/2277	13/18639	0.0769230769230769	0.629674673152934	0.816292833347388	0.999999999999966
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/2277	13/18639	0.0769230769230769	0.629674673152934	0.816292833347388	0.999999999999966
GO:0019104	DNA N-glycosylase activity	1/2277	13/18639	0.0769230769230769	0.629674673152934	0.816292833347388	0.999999999999966
GO:0046974	histone H3K9 methyltransferase activity	1/2277	13/18639	0.0769230769230769	0.629674673152934	0.816292833347388	0.999999999999966
GO:0071837	HMG box domain binding	1/2277	13/18639	0.0769230769230769	0.629674673152934	0.816292833347388	0.999999999999966
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/2277	13/18639	0.0769230769230769	0.629674673152934	0.816292833347388	0.999999999999966
GO:0097157	pre-mRNA intronic binding	1/2277	13/18639	0.0769230769230769	0.629674673152934	0.816292833347388	0.999999999999966
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/2277	13/18639	0.0769230769230769	0.629674673152934	0.816292833347388	0.999999999999966
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/2277	13/18639	0.0769230769230769	0.629674673152934	0.816292833347388	0.999999999999966
GO:0140852	histone ubiquitin ligase activity	1/2277	13/18639	0.0769230769230769	0.629674673152934	0.816292833347388	0.999999999999966
GO:1901338	catecholamine binding	1/2277	13/18639	0.0769230769230769	0.629674673152934	0.816292833347388	0.999999999999966
GO:0046915	transition metal ion transmembrane transporter activity	4/2277	45/18639	0.0888888888888889	0.727624066754502	0.816514984193168	0.999999999999966
GO:0004623	phospholipase A2 activity	3/2277	35/18639	0.0857142857142857	0.701637492941841	0.818342807715381	0.999999999999966
GO:0005343	organic acid:sodium symporter activity	3/2277	35/18639	0.0857142857142857	0.701637492941841	0.818342807715381	0.999999999999966
GO:0016229	steroid dehydrogenase activity	3/2277	35/18639	0.0857142857142857	0.701637492941841	0.818342807715381	0.999999999999966
GO:0034061	DNA polymerase activity	3/2277	35/18639	0.0857142857142857	0.701637492941841	0.818342807715381	0.999999999999966
GO:0061631	ubiquitin conjugating enzyme activity	3/2277	35/18639	0.0857142857142857	0.701637492941841	0.818342807715381	0.999999999999966
GO:0004679	AMP-activated protein kinase activity	26/2277	248/18639	0.104838709677419	0.858185643248757	0.824828663261237	0.999999999999966
GO:0005262	calcium channel activity	13/2277	131/18639	0.099236641221374	0.812328395136228	0.82511436147525	0.999999999999966
GO:0003725	double-stranded RNA binding	7/2277	75/18639	0.0933333333333333	0.764005270092227	0.825679644783438	0.999999999999966
GO:0042562	hormone binding	9/2277	94/18639	0.0957446808510638	0.783744008073333	0.826136159122533	0.999999999999966
GO:0005537	D-mannose binding	2/2277	25/18639	0.08	0.654861660079051	0.827790690651001	0.999999999999966
GO:0008139	nuclear localization sequence binding	2/2277	25/18639	0.08	0.654861660079051	0.827790690651001	0.999999999999966
GO:0015271	outward rectifier potassium channel activity	2/2277	25/18639	0.08	0.654861660079051	0.827790690651001	0.999999999999966
GO:0015296	monoatomic anion:monoatomic cation symporter activity	2/2277	25/18639	0.08	0.654861660079051	0.827790690651001	0.999999999999966
GO:0015645	fatty acid ligase activity	2/2277	25/18639	0.08	0.654861660079051	0.827790690651001	0.999999999999966
GO:0015662	P-type ion transporter activity	2/2277	25/18639	0.08	0.654861660079051	0.827790690651001	0.999999999999966
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	2/2277	25/18639	0.08	0.654861660079051	0.827790690651001	0.999999999999966
GO:0120515	fatty acid-CoA ligase activity	2/2277	25/18639	0.08	0.654861660079051	0.827790690651001	0.999999999999966
GO:0140358	P-type transmembrane transporter activity	2/2277	25/18639	0.08	0.654861660079051	0.827790690651001	0.999999999999966
GO:0030170	pyridoxal phosphate binding	5/2277	56/18639	0.0892857142857143	0.730872388481084	0.830191457269709	0.999999999999966
GO:0004033	aldo-keto reductase (NADPH) activity	3/2277	36/18639	0.0833333333333333	0.682147562582345	0.83306882033766	0.999999999999966
GO:0004190	aspartic-type endopeptidase activity	3/2277	36/18639	0.0833333333333333	0.682147562582345	0.83306882033766	0.999999999999966
GO:0016409	palmitoyltransferase activity	3/2277	36/18639	0.0833333333333333	0.682147562582345	0.83306882033766	0.999999999999966
GO:0008191	metalloendopeptidase inhibitor activity	1/2277	14/18639	0.0714285714285714	0.584697910784867	0.838750753376809	0.999999999999966
GO:0008195	phosphatidate phosphatase activity	1/2277	14/18639	0.0714285714285714	0.584697910784867	0.838750753376809	0.999999999999966
GO:0008331	high voltage-gated calcium channel activity	1/2277	14/18639	0.0714285714285714	0.584697910784867	0.838750753376809	0.999999999999966
GO:0015386	potassium:proton antiporter activity	1/2277	14/18639	0.0714285714285714	0.584697910784867	0.838750753376809	0.999999999999966
GO:0042043	neurexin family protein binding	1/2277	14/18639	0.0714285714285714	0.584697910784867	0.838750753376809	0.999999999999966
GO:0044548	S100 protein binding	1/2277	14/18639	0.0714285714285714	0.584697910784867	0.838750753376809	0.999999999999966
GO:0098847	sequence-specific single stranded DNA binding	1/2277	14/18639	0.0714285714285714	0.584697910784867	0.838750753376809	0.999999999999966
GO:1901474	azole transmembrane transporter activity	1/2277	14/18639	0.0714285714285714	0.584697910784867	0.838750753376809	0.999999999999966
GO:0020037	heme binding	14/2277	142/18639	0.0985915492957746	0.807047820519958	0.839003816535011	0.999999999999966
GO:0046943	carboxylic acid transmembrane transporter activity	19/2277	188/18639	0.101063829787234	0.827285341855185	0.841573092161475	0.999999999999966
GO:0070279	vitamin B6 binding	5/2277	57/18639	0.087719298245614	0.718050065876153	0.841602131342934	0.999999999999966
GO:0008514	organic anion transmembrane transporter activity	28/2277	269/18639	0.104089219330855	0.852050487091703	0.842948570197023	0.999999999999966
GO:0001637	G protein-coupled chemoattractant receptor activity	2/2277	26/18639	0.0769230769230769	0.629674673152934	0.844151602853019	0.999999999999966
GO:0004950	chemokine receptor activity	2/2277	26/18639	0.0769230769230769	0.629674673152934	0.844151602853019	0.999999999999966
GO:0008066	glutamate receptor activity	2/2277	26/18639	0.0769230769230769	0.629674673152934	0.844151602853019	0.999999999999966
GO:0015145	monosaccharide transmembrane transporter activity	2/2277	26/18639	0.0769230769230769	0.629674673152934	0.844151602853019	0.999999999999966
GO:0043548	phosphatidylinositol 3-kinase binding	2/2277	26/18639	0.0769230769230769	0.629674673152934	0.844151602853019	0.999999999999966
GO:0046906	tetrapyrrole binding	15/2277	152/18639	0.0986842105263158	0.807806324110672	0.844742214613719	0.999999999999966
GO:0030551	cyclic nucleotide binding	3/2277	37/18639	0.0810810810810811	0.663711141972012	0.846755098268688	0.999999999999966
GO:0070001	aspartic-type peptidase activity	3/2277	37/18639	0.0810810810810811	0.663711141972012	0.846755098268688	0.999999999999966
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	25/2277	243/18639	0.102880658436214	0.842157484669562	0.847224733825426	0.999999999999966
GO:0005342	organic acid transmembrane transporter activity	19/2277	189/18639	0.100529100529101	0.822908170734258	0.847821974645062	0.999999999999966
GO:0061980	regulatory RNA binding	5/2277	58/18639	0.0862068965517241	0.705669892326564	0.852373522368185	0.999999999999966
GO:0019955	cytokine binding	14/2277	144/18639	0.0972222222222222	0.795838823012736	0.853150458357859	0.999999999999966
GO:0140693	molecular condensate scaffold activity	4/2277	48/18639	0.0833333333333333	0.682147562582345	0.853959923890868	0.999999999999966
GO:0004089	carbonate dehydratase activity	1/2277	15/18639	0.0666666666666667	0.545718050065876	0.858464285433776	0.999999999999966
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/2277	15/18639	0.0666666666666667	0.545718050065876	0.858464285433776	0.999999999999966
GO:0008242	omega peptidase activity	1/2277	15/18639	0.0666666666666667	0.545718050065876	0.858464285433776	0.999999999999966
GO:0015116	sulfate transmembrane transporter activity	1/2277	15/18639	0.0666666666666667	0.545718050065876	0.858464285433776	0.999999999999966
GO:0030553	cGMP binding	1/2277	15/18639	0.0666666666666667	0.545718050065876	0.858464285433776	0.999999999999966
GO:0033130	acetylcholine receptor binding	1/2277	15/18639	0.0666666666666667	0.545718050065876	0.858464285433776	0.999999999999966
GO:0047372	monoacylglycerol lipase activity	1/2277	15/18639	0.0666666666666667	0.545718050065876	0.858464285433776	0.999999999999966
GO:0050780	dopamine receptor binding	1/2277	15/18639	0.0666666666666667	0.545718050065876	0.858464285433776	0.999999999999966
GO:0051371	muscle alpha-actinin binding	1/2277	15/18639	0.0666666666666667	0.545718050065876	0.858464285433776	0.999999999999966
GO:0140776	protein-containing complex destabilizing activity	1/2277	15/18639	0.0666666666666667	0.545718050065876	0.858464285433776	0.999999999999966
GO:0005104	fibroblast growth factor receptor binding	2/2277	27/18639	0.0740740740740741	0.606353388962085	0.859087226712624	0.999999999999966
GO:0005385	zinc ion transmembrane transporter activity	2/2277	27/18639	0.0740740740740741	0.606353388962085	0.859087226712624	0.999999999999966
GO:0015459	potassium channel regulator activity	5/2277	59/18639	0.0847457627118644	0.693709385676961	0.862528156374435	0.999999999999966
GO:0036002	pre-mRNA binding	5/2277	59/18639	0.0847457627118644	0.693709385676961	0.862528156374435	0.999999999999966
GO:0140713	histone chaperone activity	16/2277	164/18639	0.0975609756097561	0.798611780584209	0.86290668514061	0.999999999999966
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	23/2277	229/18639	0.100436681222707	0.822151647479158	0.868481597394553	0.999999999999966
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	5/2277	60/18639	0.0833333333333333	0.682147562582345	0.872089272443583	0.999999999999966
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	5/2277	60/18639	0.0833333333333333	0.682147562582345	0.872089272443583	0.999999999999966
GO:0015085	calcium ion transmembrane transporter activity	14/2277	147/18639	0.0952380952380952	0.779597214379823	0.872543694861895	0.999999999999966
GO:0016866	intramolecular transferase activity	2/2277	28/18639	0.0714285714285714	0.584697910784867	0.872701455640296	0.999999999999966
GO:0046625	sphingolipid binding	2/2277	28/18639	0.0714285714285714	0.584697910784867	0.872701455640296	0.999999999999966
GO:0050698	proteoglycan sulfotransferase activity	2/2277	28/18639	0.0714285714285714	0.584697910784867	0.872701455640296	0.999999999999966
GO:0051119	sugar transmembrane transporter activity	2/2277	28/18639	0.0714285714285714	0.584697910784867	0.872701455640296	0.999999999999966
GO:0051393	alpha-actinin binding	2/2277	28/18639	0.0714285714285714	0.584697910784867	0.872701455640296	0.999999999999966
GO:0048020	CCR chemokine receptor binding	4/2277	50/18639	0.08	0.654861660079051	0.875142614117119	0.999999999999966
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	1/2277	16/18639	0.0625	0.511610671936759	0.875768668061959	0.999999999999966
GO:0008142	oxysterol binding	1/2277	16/18639	0.0625	0.511610671936759	0.875768668061959	0.999999999999966
GO:0015385	sodium:proton antiporter activity	1/2277	16/18639	0.0625	0.511610671936759	0.875768668061959	0.999999999999966
GO:0019841	retinol binding	1/2277	16/18639	0.0625	0.511610671936759	0.875768668061959	0.999999999999966
GO:0055102	lipase inhibitor activity	1/2277	16/18639	0.0625	0.511610671936759	0.875768668061959	0.999999999999966
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/2277	16/18639	0.0625	0.511610671936759	0.875768668061959	0.999999999999966
GO:0030971	receptor tyrosine kinase binding	7/2277	81/18639	0.0864197530864197	0.707412287122432	0.879888928085567	0.999999999999966
GO:0015144	carbohydrate transmembrane transporter activity	3/2277	40/18639	0.075	0.613932806324111	0.882107291030099	0.999999999999966
GO:0050997	quaternary ammonium group binding	3/2277	40/18639	0.075	0.613932806324111	0.882107291030099	0.999999999999966
GO:0071855	neuropeptide receptor binding	3/2277	40/18639	0.075	0.613932806324111	0.882107291030099	0.999999999999966
GO:0016298	lipase activity	12/2277	130/18639	0.0923076923076923	0.755609607783521	0.883817823451124	0.999999999999966
GO:0043236	laminin binding	2/2277	29/18639	0.0689655172413793	0.564535913861251	0.885094081318358	0.999999999999966
GO:0051082	unfolded protein binding	11/2277	121/18639	0.0909090909090909	0.744160977362558	0.88716224729774	0.999999999999966
GO:0031072	heat shock protein binding	12/2277	131/18639	0.0916030534351145	0.749841595510364	0.889737500289027	0.999999999999966
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/2277	17/18639	0.0588235294117647	0.481515926528714	0.890958204808075	0.999999999999966
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/2277	17/18639	0.0588235294117647	0.481515926528714	0.890958204808075	0.999999999999966
GO:0045125	bioactive lipid receptor activity	1/2277	17/18639	0.0588235294117647	0.481515926528714	0.890958204808075	0.999999999999966
GO:0045236	CXCR chemokine receptor binding	1/2277	17/18639	0.0588235294117647	0.481515926528714	0.890958204808075	0.999999999999966
GO:0051787	misfolded protein binding	1/2277	17/18639	0.0588235294117647	0.481515926528714	0.890958204808075	0.999999999999966
GO:0008227	G protein-coupled amine receptor activity	3/2277	41/18639	0.0731707317073171	0.598958835438157	0.892165329756663	0.999999999999966
GO:0042287	MHC protein binding	3/2277	41/18639	0.0731707317073171	0.598958835438157	0.892165329756663	0.999999999999966
GO:0140597	protein carrier chaperone	18/2277	188/18639	0.0957446808510638	0.783744008073333	0.892612547984701	0.999999999999966
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	4/2277	52/18639	0.0769230769230769	0.629674673152934	0.893612801457501	0.999999999999966
GO:0051213	dioxygenase activity	8/2277	93/18639	0.0860215053763441	0.704152322665647	0.89476701428948	0.999999999999966
GO:0016769	transferase activity, transferring nitrogenous groups	2/2277	30/18639	0.0666666666666667	0.545718050065876	0.896360245195464	0.999999999999966
GO:0051721	protein phosphatase 2A binding	2/2277	30/18639	0.0666666666666667	0.545718050065876	0.896360245195464	0.999999999999966
GO:0070566	adenylyltransferase activity	2/2277	30/18639	0.0666666666666667	0.545718050065876	0.896360245195464	0.999999999999966
GO:0016410	N-acyltransferase activity	8/2277	94/18639	0.0851063829787234	0.696661340509629	0.901151279886406	0.999999999999966
GO:0051879	Hsp90 protein binding	3/2277	42/18639	0.0714285714285714	0.584697910784867	0.901446289649055	0.999999999999966
GO:0005544	calcium-dependent phospholipid binding	4/2277	53/18639	0.0754716981132075	0.617794018942501	0.901914690405637	0.999999999999966
GO:0008083	growth factor activity	15/2277	162/18639	0.0925925925925926	0.757941736202606	0.902831640372197	0.999999999999966
GO:0008308	voltage-gated monoatomic anion channel activity	1/2277	18/18639	0.0555555555555556	0.454765041721563	0.90429126074471	0.999999999999966
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	1/2277	18/18639	0.0555555555555556	0.454765041721563	0.90429126074471	0.999999999999966
GO:0022851	GABA-gated chloride ion channel activity	1/2277	18/18639	0.0555555555555556	0.454765041721563	0.90429126074471	0.999999999999966
GO:0050811	GABA receptor binding	1/2277	18/18639	0.0555555555555556	0.454765041721563	0.90429126074471	0.999999999999966
GO:0005164	tumor necrosis factor receptor binding	2/2277	31/18639	0.0645161290322581	0.528114241999235	0.906590085082097	0.999999999999966
GO:0005184	neuropeptide hormone activity	2/2277	31/18639	0.0645161290322581	0.528114241999235	0.906590085082097	0.999999999999966
GO:0003925	G protein activity	4/2277	54/18639	0.0740740740740741	0.606353388962085	0.909638484512793	0.999999999999966
GO:0015106	bicarbonate transmembrane transporter activity	2/2277	32/18639	0.0625	0.511610671936759	0.91586853739816	0.999999999999966
GO:0047498	calcium-dependent phospholipase A2 activity	2/2277	32/18639	0.0625	0.511610671936759	0.91586853739816	0.999999999999966
GO:0160041	neuropeptide activity	2/2277	32/18639	0.0625	0.511610671936759	0.91586853739816	0.999999999999966
GO:0004890	GABA-A receptor activity	1/2277	19/18639	0.0526315789473684	0.430830039525692	0.915994649353501	0.999999999999966
GO:0005520	insulin-like growth factor binding	1/2277	19/18639	0.0526315789473684	0.430830039525692	0.915994649353501	0.999999999999966
GO:0016918	retinal binding	1/2277	19/18639	0.0526315789473684	0.430830039525692	0.915994649353501	0.999999999999966
GO:0022821	solute:potassium antiporter activity	1/2277	19/18639	0.0526315789473684	0.430830039525692	0.915994649353501	0.999999999999966
GO:0022840	leak channel activity	1/2277	19/18639	0.0526315789473684	0.430830039525692	0.915994649353501	0.999999999999966
GO:0022842	narrow pore channel activity	1/2277	19/18639	0.0526315789473684	0.430830039525692	0.915994649353501	0.999999999999966
GO:0034987	immunoglobulin receptor binding	1/2277	19/18639	0.0526315789473684	0.430830039525692	0.915994649353501	0.999999999999966
GO:0097001	ceramide binding	1/2277	19/18639	0.0526315789473684	0.430830039525692	0.915994649353501	0.999999999999966
GO:0004519	endonuclease activity	11/2277	127/18639	0.0866141732283465	0.709003765833619	0.919260693369021	0.999999999999966
GO:0170055	lipid transmembrane transporter activity	4/2277	56/18639	0.0714285714285714	0.584697910784867	0.923479867433689	0.999999999999966
GO:0019956	chemokine binding	2/2277	33/18639	0.0606060606060606	0.496107318241706	0.924275262344253	0.999999999999966
GO:0008173	RNA methyltransferase activity	5/2277	67/18639	0.0746268656716418	0.610878414252846	0.924405514264127	0.999999999999966
GO:0004197	cysteine-type endopeptidase activity	7/2277	88/18639	0.0795454545454545	0.651140855192239	0.924605231578529	0.999999999999966
GO:0015095	magnesium ion transmembrane transporter activity	1/2277	20/18639	0.05	0.409288537549407	0.926267484123752	0.999999999999966
GO:0030627	pre-mRNA 5'-splice site binding	1/2277	20/18639	0.05	0.409288537549407	0.926267484123752	0.999999999999966
GO:0031418	L-ascorbic acid binding	1/2277	20/18639	0.05	0.409288537549407	0.926267484123752	0.999999999999966
GO:0061608	nuclear import signal receptor activity	1/2277	20/18639	0.05	0.409288537549407	0.926267484123752	0.999999999999966
GO:1990841	promoter-specific chromatin binding	5/2277	68/18639	0.0735294117647059	0.601894908160893	0.930075741261614	0.999999999999966
GO:0008175	tRNA methyltransferase activity	2/2277	34/18639	0.0588235294117647	0.481515926528714	0.931884664936366	0.999999999999966
GO:0051427	hormone receptor binding	2/2277	34/18639	0.0588235294117647	0.481515926528714	0.931884664936366	0.999999999999966
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	1/2277	21/18639	0.0476190476190476	0.389798607189912	0.935284560156311	0.999999999999966
GO:0035613	RNA stem-loop binding	1/2277	21/18639	0.0476190476190476	0.389798607189912	0.935284560156311	0.999999999999966
GO:0036122	BMP binding	1/2277	21/18639	0.0476190476190476	0.389798607189912	0.935284560156311	0.999999999999966
GO:0070182	DNA polymerase binding	1/2277	21/18639	0.0476190476190476	0.389798607189912	0.935284560156311	0.999999999999966
GO:1904047	S-adenosyl-L-methionine binding	1/2277	21/18639	0.0476190476190476	0.389798607189912	0.935284560156311	0.999999999999966
GO:0008028	monocarboxylic acid transmembrane transporter activity	5/2277	70/18639	0.0714285714285714	0.584697910784867	0.940289511295627	0.999999999999966
GO:0005243	gap junction channel activity	1/2277	22/18639	0.0454545454545455	0.372080488681279	0.943199323102067	0.999999999999966
GO:0008970	phospholipase A1 activity	1/2277	22/18639	0.0454545454545455	0.372080488681279	0.943199323102067	0.999999999999966
GO:0004869	cysteine-type endopeptidase inhibitor activity	2/2277	36/18639	0.0555555555555556	0.454765041721563	0.944983470162235	0.999999999999966
GO:0001664	G protein-coupled receptor binding	28/2277	297/18639	0.0942760942760943	0.771722495042653	0.945831999217585	0.999999999999966
GO:0061135	endopeptidase regulator activity	16/2277	184/18639	0.0869565217391304	0.711806152259838	0.948386479236872	0.999999999999966
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	1/2277	23/18639	0.0434782608695652	0.355903076129919	0.950146475774173	0.999999999999966
GO:0004022	alcohol dehydrogenase (NAD+) activity	1/2277	23/18639	0.0434782608695652	0.355903076129919	0.950146475774173	0.999999999999966
GO:0016493	C-C chemokine receptor activity	1/2277	23/18639	0.0434782608695652	0.355903076129919	0.950146475774173	0.999999999999966
GO:0016917	GABA receptor activity	1/2277	23/18639	0.0434782608695652	0.355903076129919	0.950146475774173	0.999999999999966
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	1/2277	23/18639	0.0434782608695652	0.355903076129919	0.950146475774173	0.999999999999966
GO:0022829	wide pore channel activity	2/2277	37/18639	0.0540540540540541	0.442474094648008	0.950596519984724	0.999999999999966
GO:0015293	symporter activity	12/2277	146/18639	0.0821917808219178	0.672803075423683	0.952530666771865	0.999999999999966
GO:0140375	immune receptor activity	13/2277	156/18639	0.0833333333333333	0.682147562582345	0.952550046720289	0.999999999999966
GO:0032813	tumor necrosis factor receptor superfamily binding	3/2277	50/18639	0.06	0.491146245059288	0.953269535484508	0.999999999999966
GO:0005501	retinoid binding	2/2277	38/18639	0.0526315789473684	0.430830039525692	0.95565995071606	0.999999999999966
GO:0019840	isoprenoid binding	2/2277	38/18639	0.0526315789473684	0.430830039525692	0.95565995071606	0.999999999999966
GO:0001091	RNA polymerase II general transcription initiation factor binding	1/2277	24/18639	0.0416666666666667	0.341073781291173	0.956244266634842	0.999999999999966
GO:0004806	triacylglycerol lipase activity	1/2277	24/18639	0.0416666666666667	0.341073781291173	0.956244266634842	0.999999999999966
GO:0005315	phosphate transmembrane transporter activity	1/2277	24/18639	0.0416666666666667	0.341073781291173	0.956244266634842	0.999999999999966
GO:0019957	C-C chemokine binding	1/2277	24/18639	0.0416666666666667	0.341073781291173	0.956244266634842	0.999999999999966
GO:0030215	semaphorin receptor binding	1/2277	24/18639	0.0416666666666667	0.341073781291173	0.956244266634842	0.999999999999966
GO:0005126	cytokine receptor binding	25/2277	275/18639	0.0909090909090909	0.744160977362558	0.958763258925917	0.999999999999966
GO:0031490	chromatin DNA binding	10/2277	128/18639	0.078125	0.639513339920949	0.958895618217857	0.999999999999966
GO:0005261	monoatomic cation channel activity	32/2277	341/18639	0.093841642228739	0.768166170180705	0.958996752836517	0.999999999999966
GO:0030159	signaling receptor complex adaptor activity	3/2277	52/18639	0.0576923076923077	0.472256004864701	0.96146997378776	0.999999999999966
GO:0005251	delayed rectifier potassium channel activity	1/2277	25/18639	0.04	0.327430830039526	0.961596498967501	0.999999999999966
GO:0008483	transaminase activity	1/2277	25/18639	0.04	0.327430830039526	0.961596498967501	0.999999999999966
GO:0047617	fatty acyl-CoA hydrolase activity	1/2277	25/18639	0.04	0.327430830039526	0.961596498967501	0.999999999999966
GO:0019842	vitamin binding	12/2277	150/18639	0.08	0.654861660079051	0.962732655985631	0.999999999999966
GO:0032451	demethylase activity	2/2277	40/18639	0.05	0.409288537549407	0.964335626096193	0.999999999999966
GO:0061791	GTPase motor activity	2/2277	40/18639	0.05	0.409288537549407	0.964335626096193	0.999999999999966
GO:1990606	membrane scission GTPase motor activity	2/2277	40/18639	0.05	0.409288537549407	0.964335626096193	0.999999999999966
GO:0003724	RNA helicase activity	5/2277	77/18639	0.0649350649350649	0.53154355525897	0.966292772152913	0.999999999999966
GO:0005112	Notch binding	1/2277	26/18639	0.0384615384615385	0.314837336576467	0.966294294812081	0.999999999999966
GO:0005227	calcium-activated cation channel activity	1/2277	26/18639	0.0384615384615385	0.314837336576467	0.966294294812081	0.999999999999966
GO:0016289	acyl-CoA hydrolase activity	1/2277	26/18639	0.0384615384615385	0.314837336576467	0.966294294812081	0.999999999999966
GO:0051139	metal cation:proton antiporter activity	1/2277	26/18639	0.0384615384615385	0.314837336576467	0.966294294812081	0.999999999999966
GO:0015108	chloride transmembrane transporter activity	9/2277	121/18639	0.0743801652892562	0.608858981478457	0.967295221334832	0.999999999999966
GO:0004812	aminoacyl-tRNA ligase activity	2/2277	41/18639	0.0487804878048781	0.399305890292105	0.968036666934117	0.999999999999966
GO:0016875	ligase activity, forming carbon-oxygen bonds	2/2277	41/18639	0.0487804878048781	0.399305890292105	0.968036666934117	0.999999999999966
GO:0008236	serine-type peptidase activity	16/2277	194/18639	0.0824742268041237	0.675115113483558	0.970136029414335	0.999999999999966
GO:0008395	steroid hydroxylase activity	1/2277	27/18639	0.037037037037037	0.303176694481042	0.970417643585137	0.999999999999966
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	1/2277	27/18639	0.037037037037037	0.303176694481042	0.970417643585137	0.999999999999966
GO:0023026	MHC class II protein complex binding	1/2277	27/18639	0.037037037037037	0.303176694481042	0.970417643585137	0.999999999999966
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	1/2277	27/18639	0.037037037037037	0.303176694481042	0.970417643585137	0.999999999999966
GO:0008186	ATP-dependent activity, acting on RNA	5/2277	79/18639	0.0632911392405063	0.518086756391655	0.971517133251499	0.999999999999966
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	3/2277	56/18639	0.0535714285714286	0.43852343308865	0.97397799955146	0.999999999999966
GO:0005242	inward rectifier potassium channel activity	1/2277	28/18639	0.0357142857142857	0.292348955392434	0.974036761657168	0.999999999999966
GO:0008527	taste receptor activity	1/2277	28/18639	0.0357142857142857	0.292348955392434	0.974036761657168	0.999999999999966
GO:0141052	histone H3 demethylase activity	1/2277	28/18639	0.0357142857142857	0.292348955392434	0.974036761657168	0.999999999999966
GO:0015297	antiporter activity	10/2277	135/18639	0.0740740740740741	0.606353388962085	0.974177766349994	0.999999999999966
GO:0005253	monoatomic anion channel activity	7/2277	103/18639	0.0679611650485437	0.556314517057447	0.974748486334752	0.999999999999966
GO:0017171	serine hydrolase activity	16/2277	198/18639	0.0808080808080808	0.661476424322274	0.976244832369336	0.999999999999966
GO:0005319	lipid transporter activity	14/2277	178/18639	0.0786516853932584	0.643824665808056	0.976623424728454	0.999999999999966
GO:0001046	core promoter sequence-specific DNA binding	2/2277	44/18639	0.0454545454545455	0.372080488681279	0.977049496463204	0.999999999999966
GO:0035250	UDP-galactosyltransferase activity	1/2277	29/18639	0.0344827586206897	0.282267956930626	0.977213285954983	0.999999999999966
GO:0051861	glycolipid binding	1/2277	29/18639	0.0344827586206897	0.282267956930626	0.977213285954983	0.999999999999966
GO:0019783	ubiquitin-like protein peptidase activity	9/2277	127/18639	0.0708661417322835	0.580093990227506	0.978545475125241	0.999999999999966
GO:0005254	chloride channel activity	5/2277	83/18639	0.0602409638554217	0.493118719939045	0.97978628212189	0.999999999999966
GO:0001965	G-protein alpha-subunit binding	1/2277	30/18639	0.0333333333333333	0.272859025032938	0.980001321843242	0.999999999999966
GO:0022839	monoatomic ion-gated channel activity	1/2277	30/18639	0.0333333333333333	0.272859025032938	0.980001321843242	0.999999999999966
GO:0032452	histone demethylase activity	1/2277	30/18639	0.0333333333333333	0.272859025032938	0.980001321843242	0.999999999999966
GO:0008327	methyl-CpG binding	1/2277	31/18639	0.032258064516129	0.264057120999617	0.982448363068613	0.999999999999966
GO:0140457	protein demethylase activity	1/2277	31/18639	0.032258064516129	0.264057120999617	0.982448363068613	0.999999999999966
GO:0030594	neurotransmitter receptor activity	6/2277	97/18639	0.0618556701030928	0.506336335112669	0.983447372784638	0.999999999999966
GO:0099095	ligand-gated monoatomic anion channel activity	2/2277	47/18639	0.0425531914893617	0.348330670254815	0.983578650544793	0.999999999999966
GO:0005216	monoatomic ion channel activity	41/2277	448/18639	0.0915178571428571	0.749144198193111	0.984024495588368	0.999999999999966
GO:0015081	sodium ion transmembrane transporter activity	12/2277	164/18639	0.0731707317073171	0.598958835438157	0.984814917100365	0.999999999999966
GO:0044183	protein folding chaperone	4/2277	75/18639	0.0533333333333333	0.436574440052701	0.986043917917319	0.999999999999966
GO:0019239	deaminase activity	1/2277	33/18639	0.0303030303030303	0.248053659120853	0.986481125537948	0.999999999999966
GO:0042277	peptide binding	20/2277	249/18639	0.0803212851405622	0.657491626585393	0.987140208019827	0.999999999999966
GO:0022824	transmitter-gated monoatomic ion channel activity	3/2277	63/18639	0.0476190476190476	0.389798607189912	0.987147404469355	0.999999999999966
GO:0022835	transmitter-gated channel activity	3/2277	63/18639	0.0476190476190476	0.389798607189912	0.987147404469355	0.999999999999966
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/2277	34/18639	0.0294117647058824	0.240757963264357	0.988135563737996	0.999999999999966
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	1/2277	34/18639	0.0294117647058824	0.240757963264357	0.988135563737996	0.999999999999966
GO:0004536	DNA nuclease activity	3/2277	64/18639	0.046875	0.383708003952569	0.988399349068739	0.999999999999966
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	44/2277	484/18639	0.0909090909090909	0.744160977362558	0.988458259147662	0.999999999999966
GO:0030414	peptidase inhibitor activity	12/2277	169/18639	0.0710059171597633	0.581238159833478	0.989174385497537	0.999999999999966
GO:0008509	monoatomic anion transmembrane transporter activity	10/2277	149/18639	0.0671140939597315	0.54938058731464	0.990408687451956	0.999999999999966
GO:0015370	solute:sodium symporter activity	4/2277	79/18639	0.0506329113924051	0.414469405113324	0.990466107985305	0.999999999999966
GO:0001216	DNA-binding transcription activator activity	44/2277	491/18639	0.0896130346232179	0.733551757726025	0.991460559865587	0.999999999999966
GO:0016251	RNA polymerase II general transcription initiation factor activity	2/2277	53/18639	0.0377358490566038	0.308897009471251	0.991669114435961	0.999999999999966
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	2/2277	53/18639	0.0377358490566038	0.308897009471251	0.991669114435961	0.999999999999966
GO:0015291	secondary active transmembrane transporter activity	23/2277	287/18639	0.0801393728222996	0.656002534051314	0.991705182580216	0.999999999999966
GO:0023023	MHC protein complex binding	1/2277	37/18639	0.027027027027027	0.221237047324004	0.991980499977833	0.999999999999966
GO:0030280	structural constituent of skin epidermis	1/2277	37/18639	0.027027027027027	0.221237047324004	0.991980499977833	0.999999999999966
GO:0035591	signaling adaptor activity	8/2277	129/18639	0.062015503875969	0.507644697735699	0.992037805252018	0.999999999999966
GO:0005548	phospholipid transporter activity	3/2277	68/18639	0.0441176470588235	0.361136944896536	0.992330244572051	0.999999999999966
GO:0140223	general transcription initiation factor activity	3/2277	68/18639	0.0441176470588235	0.361136944896536	0.992330244572051	0.999999999999966
GO:0046982	protein heterodimerization activity	31/2277	369/18639	0.0840108401084011	0.687693477725291	0.992749282184334	0.999999999999966
GO:0004867	serine-type endopeptidase inhibitor activity	5/2277	95/18639	0.0526315789473684	0.430830039525692	0.993082481371674	0.999999999999966
GO:0098960	postsynaptic neurotransmitter receptor activity	3/2277	69/18639	0.0434782608695652	0.355903076129919	0.993090275194339	0.999999999999966
GO:0015103	inorganic anion transmembrane transporter activity	11/2277	165/18639	0.0666666666666667	0.545718050065876	0.993337167055565	0.999999999999966
GO:0004252	serine-type endopeptidase activity	12/2277	176/18639	0.0681818181818182	0.558120733021919	0.993355659375551	0.999999999999966
GO:0004896	cytokine receptor activity	5/2277	96/18639	0.0520833333333333	0.426342226613966	0.993690470539752	0.999999999999966
GO:0005179	hormone activity	8/2277	132/18639	0.0606060606060606	0.496107318241706	0.993739934423638	0.999999999999966
GO:0071949	FAD binding	1/2277	40/18639	0.025	0.204644268774704	0.99457976429679	0.999999999999966
GO:0140662	ATP-dependent protein folding chaperone	1/2277	40/18639	0.025	0.204644268774704	0.99457976429679	0.999999999999966
GO:0004175	endopeptidase activity	34/2277	405/18639	0.0839506172839506	0.687200507490363	0.994784789081421	0.999999999999966
GO:0005125	cytokine activity	17/2277	234/18639	0.0726495726495727	0.59469274686666	0.995080499202942	0.999999999999966
GO:0050660	flavin adenine dinucleotide binding	4/2277	86/18639	0.0465116279069767	0.380733523301774	0.99517929491801	0.999999999999966
GO:0140828	metal cation:monoatomic cation antiporter activity	1/2277	41/18639	0.024390243902439	0.199652945146052	0.995243341730857	0.999999999999966
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	3/2277	73/18639	0.0410958904109589	0.336401537711841	0.99546360507009	0.999999999999966
GO:0099094	ligand-gated monoatomic cation channel activity	8/2277	136/18639	0.0588235294117647	0.481515926528714	0.995479817672352	0.999999999999966
GO:0001217	DNA-binding transcription repressor activity	21/2277	278/18639	0.0755395683453237	0.618349589103421	0.995723759194209	0.999999999999966
GO:0015079	potassium ion transmembrane transporter activity	10/2277	160/18639	0.0625	0.511610671936759	0.995810541415317	0.999999999999966
GO:0004520	DNA endonuclease activity	1/2277	42/18639	0.0238095238095238	0.194899303594956	0.995825711387747	0.999999999999966
GO:0004866	endopeptidase inhibitor activity	10/2277	161/18639	0.062111801242236	0.508432965899885	0.996122116114019	0.999999999999966
GO:0005244	voltage-gated monoatomic ion channel activity	11/2277	173/18639	0.0635838150289017	0.520482533299824	0.996319177941846	0.999999999999966
GO:0101005	deubiquitinase activity	6/2277	115/18639	0.0521739130434783	0.427083691355903	0.99652625951797	0.999999999999966
GO:0015276	ligand-gated monoatomic ion channel activity	12/2277	186/18639	0.0645161290322581	0.528114241999235	0.996780361032161	0.999999999999966
GO:0022832	voltage-gated channel activity	11/2277	175/18639	0.0628571428571429	0.514534161490683	0.996836541063123	0.999999999999966
GO:0008234	cysteine-type peptidase activity	12/2277	187/18639	0.0641711229946524	0.525290101667688	0.99701033613455	0.999999999999966
GO:0140303	intramembrane lipid transporter activity	1/2277	45/18639	0.0222222222222222	0.181906016688625	0.997178990897781	0.999999999999966
GO:0022834	ligand-gated channel activity	12/2277	188/18639	0.0638297872340425	0.522496005382222	0.997224690671661	0.999999999999966
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	19/2277	268/18639	0.0708955223880597	0.580334493540204	0.9978560089908	0.999999999999966
GO:0004843	cysteine-type deubiquitinase activity	5/2277	108/18639	0.0462962962962963	0.378970868101303	0.997964177164654	0.999999999999966
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	11/2277	181/18639	0.0607734806629834	0.497477780446793	0.998005967738036	0.999999999999966
GO:0005267	potassium channel activity	6/2277	124/18639	0.0483870967741935	0.396085681499426	0.9984750390016	0.999999999999966
GO:0005249	voltage-gated potassium channel activity	4/2277	98/18639	0.0408163265306122	0.334113091877067	0.99855847963545	0.999999999999966
GO:0017046	peptide hormone binding	1/2277	53/18639	0.0188679245283019	0.154448504735625	0.9990081337931	0.999999999999966
GO:0022843	voltage-gated monoatomic cation channel activity	7/2277	143/18639	0.048951048951049	0.400702064733685	0.999142612596451	0.999999999999966
GO:0004497	monooxygenase activity	4/2277	106/18639	0.0377358490566038	0.308897009471251	0.999369786058943	0.999999999999966
GO:0022836	gated channel activity	21/2277	318/18639	0.0660377358490566	0.540569766574689	0.999683045667092	0.999999999999966
GO:0046873	metal ion transmembrane transporter activity	32/2277	450/18639	0.0711111111111111	0.582099253403601	0.999872146000229	0.999999999999966
GO:0001653	peptide receptor activity	4/2277	128/18639	0.03125	0.255805335968379	0.999939831425648	0.999999999999966
GO:0008528	G protein-coupled peptide receptor activity	3/2277	122/18639	0.0245901639344262	0.20128944469643	0.999980727912761	0.999999999999966
GO:0003730	mRNA 3'-UTR binding	13/2277	262/18639	0.049618320610687	0.406164197568114	0.999982053892611	0.999999999999966
GO:0045182	translation regulator activity	11/2277	356/18639	0.0308988764044944	0.252931118710308	0.999999999854212	0.999999999999966
GO:0030371	translation repressor activity	5/2277	329/18639	0.0151975683890578	0.124403810805291	0.999999999999966	0.999999999999966