ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	146/3891	175/18639	0.834285714285714	3.99646657120828	8.36303522695898e-71	1.11981041688981e-67
GO:0009055	electron transfer activity	78/3891	116/18639	0.672413793103448	3.22105389094196	4.79469799212123e-27	3.21005030572516e-24
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	54/3891	68/18639	0.794117647058823	3.80405007029797	7.03335614677813e-25	3.13922129351197e-22
GO:0003954	NADH dehydrogenase activity	37/3891	44/18639	0.840909090909091	4.02819443470947	4.63832690851035e-19	1.55267993262384e-16
GO:0008137	NADH dehydrogenase (ubiquinone) activity	34/3891	41/18639	0.829268292682927	3.97243169039246	3.0658484837093e-17	6.85890932650382e-15
GO:0015078	proton transmembrane transporter activity	90/3891	185/18639	0.486486486486487	2.33040905207443	3.07344704697707e-17	6.85890932650382e-15
GO:0022853	active monoatomic ion transmembrane transporter activity	65/3891	118/18639	0.550847457627119	2.63871646433099	3.15023092310245e-16	6.02594172290597e-14
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	40/3891	58/18639	0.689655172413793	3.30364501635073	4.04948437142051e-15	6.77782446666509e-13
GO:0019843	rRNA binding	42/3891	65/18639	0.646153846153846	3.09526125378091	2.82760445096898e-14	4.20684706649719e-12
GO:0015399	primary active transmembrane transporter activity	75/3891	166/18639	0.451807228915663	2.16428551522977	1.56906611639723e-12	2.10097952985589e-10
GO:0016651	oxidoreductase activity, acting on NAD(P)H	47/3891	88/18639	0.534090909090909	2.5584478166398	1.72647013254251e-11	2.10158500679492e-09
GO:0016853	isomerase activity	73/3891	180/18639	0.405555555555556	1.94272680544847	1.3581509731912e-09	1.51547012758585e-07
GO:0043021	ribonucleoprotein complex binding	68/3891	177/18639	0.384180790960452	1.84033558537956	6.34741648215586e-08	6.53783897662054e-06
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	14/3891	18/18639	0.777777777777778	3.72577743510666	3.7844249291113e-07	3.61953212862859e-05
GO:0016675	oxidoreductase activity, acting on a heme group of donors	13/3891	16/18639	0.8125	3.8921067848882	4.14046499344731e-07	3.69605508415063e-05
GO:0044389	ubiquitin-like protein ligase binding	104/3891	322/18639	0.322981366459627	1.54717288343382	9.20069364024371e-07	7.69983049017895e-05
GO:0016860	intramolecular oxidoreductase activity	27/3891	53/18639	0.509433962264151	2.44033400736096	1.19189654964988e-06	9.15058259303839e-05
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	22/3891	39/18639	0.564102564102564	2.70221220568175	1.23010072199172e-06	9.15058259303839e-05
GO:0016859	cis-trans isomerase activity	23/3891	42/18639	0.547619047619048	2.62325145941183	1.4292684839023e-06	0.000100725815786588
GO:0004129	cytochrome-c oxidase activity	12/3891	15/18639	0.8	3.83222821896685	1.62231427844789e-06	0.000103441848516272
GO:0055105	ubiquitin-protein transferase inhibitor activity	12/3891	15/18639	0.8	3.83222821896685	1.62231427844789e-06	0.000103441848516272
GO:0031625	ubiquitin protein ligase binding	97/3891	302/18639	0.321192052980132	1.53860156142295	2.76475815154647e-06	0.000168273234769124
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	29/3891	61/18639	0.475409836065574	2.27734873668112	2.9903687934052e-06	0.000174091470189981
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	20/3891	36/18639	0.555555555555556	2.66126959650475	5.17377550920067e-06	0.000266449438723834
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	20/3891	36/18639	0.555555555555556	2.66126959650475	5.17377550920067e-06	0.000266449438723834
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	20/3891	36/18639	0.555555555555556	2.66126959650475	5.17377550920067e-06	0.000266449438723834
GO:0032977	membrane insertase activity	12/3891	17/18639	0.705882352941177	3.38137784026486	1.4430445828018e-05	0.000715643220878373
GO:0031386	protein tag activity	11/3891	15/18639	0.733333333333333	3.51287586738628	1.90213702975333e-05	0.000878262580289554
GO:0141047	molecular tag activity	11/3891	15/18639	0.733333333333333	3.51287586738628	1.90213702975333e-05	0.000878262580289554
GO:0008135	translation factor activity, RNA binding	34/3891	83/18639	0.409638554216867	1.96228553380832	2.51909340364381e-05	0.00112435535582635
GO:0003743	translation initiation factor activity	24/3891	51/18639	0.470588235294118	2.25425189350991	2.60321071782852e-05	0.00112441908102335
GO:1990948	ubiquitin ligase inhibitor activity	9/3891	11/18639	0.818181818181818	3.91932431485246	2.71497017769166e-05	0.00113604533372786
GO:0051537	2 iron, 2 sulfur cluster binding	16/3891	28/18639	0.571428571428571	2.7373058706906	2.86401448639222e-05	0.00116209557493309
GO:0180051	translation factor activity	34/3891	84/18639	0.404761904761905	1.93892499173918	3.39009581368828e-05	0.00133509949839077
GO:0043022	ribosome binding	42/3891	112/18639	0.375	1.79635697764071	3.86552802381733e-05	0.00147884057825469
GO:0016530	metallochaperone activity	10/3891	14/18639	0.714285714285714	3.42163233836326	6.74942467279954e-05	0.00251041101024405
GO:0015252	proton channel activity	15/3891	27/18639	0.555555555555556	2.66126959650475	7.9636886680443e-05	0.00288199435851657
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	25/3891	60/18639	0.416666666666667	1.99595219737857	0.000208688052377711	0.00735350795088829
GO:0051540	metal cluster binding	30/3891	77/18639	0.38961038961039	1.8663449118345	0.000216248210985718	0.00742452191050967
GO:0016504	peptidase activator activity	24/3891	57/18639	0.421052631578947	2.01696222050887	0.000229317458180871	0.00767640191260466
GO:0140104	molecular carrier activity	75/3891	249/18639	0.301204819277108	1.44285701015318	0.000343274379799896	0.0112108388915137
GO:0055106	ubiquitin-protein transferase regulator activity	17/3891	36/18639	0.472222222222222	2.26207915702904	0.00036814145693851	0.0117367002581111
GO:0051536	iron-sulfur cluster binding	29/3891	76/18639	0.381578947368421	1.82787201233616	0.00041314319744829	0.012865087008913
GO:0016829	lyase activity	62/3891	200/18639	0.31	1.48498843484965	0.000470576679317647	0.0143205039455984
GO:0019205	nucleobase-containing compound kinase activity	19/3891	44/18639	0.431818181818182	2.06853227728324	0.000690593113581024	0.0205489817574442
GO:0016505	peptidase activator activity involved in apoptotic process	11/3891	20/18639	0.55	2.63465690053971	0.000821469966897219	0.0236379878309457
GO:0140297	DNA-binding transcription factor binding	131/3891	488/18639	0.26844262295082	1.28591674355701	0.000829712791676213	0.0236379878309457
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	23/3891	59/18639	0.389830508474576	1.86739934398808	0.00112266057355007	0.0309050011056282
GO:0033204	ribonuclease P RNA binding	7/3891	10/18639	0.7	3.35319969159599	0.00113095224359655	0.0309050011056282
GO:0051082	unfolded protein binding	40/3891	121/18639	0.330578512396694	1.58356537973837	0.00117758706572911	0.0315357816202255
GO:0004601	peroxidase activity	22/3891	57/18639	0.385964912280702	1.84888203546646	0.0016604893882084	0.0433789379213048
GO:0004519	endonuclease activity	41/3891	127/18639	0.322834645669291	1.54647004899253	0.00171960249860789	0.0433789379213048
GO:0140098	catalytic activity, acting on RNA	105/3891	387/18639	0.271317829457364	1.29968980294418	0.00177693040159355	0.0433789379213048
GO:0016209	antioxidant activity	30/3891	86/18639	0.348837209302326	1.67102974664252	0.00181881415326284	0.0433789379213048
GO:0019001	guanyl nucleotide binding	108/3891	400/18639	0.27	1.29337702390131	0.00183760477165364	0.0433789379213048
GO:0032561	guanyl ribonucleotide binding	108/3891	400/18639	0.27	1.29337702390131	0.00183760477165364	0.0433789379213048
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	21/3891	54/18639	0.388888888888889	1.86288871755333	0.00187899805783098	0.0433789379213048
GO:0051287	NAD binding	21/3891	54/18639	0.388888888888889	1.86288871755333	0.00187899805783098	0.0433789379213048
GO:0043023	ribosomal large subunit binding	9/3891	16/18639	0.5625	2.69453546646106	0.00202164493841126	0.0458810605514012
GO:0061133	endopeptidase activator activity	11/3891	22/18639	0.5	2.39514263685428	0.00227706681839383	0.0508165411638222
GO:0005525	GTP binding	102/3891	378/18639	0.26984126984127	1.29261666115945	0.00246150252666168	0.0540319980852458
GO:0070990	snRNP binding	7/3891	11/18639	0.636363636363636	3.04836335599636	0.0025490023214377	0.0543380344374061
GO:0004521	RNA endonuclease activity	26/3891	73/18639	0.356164383561644	1.70612900159483	0.00255660654933277	0.0543380344374061
GO:0030515	snoRNA binding	14/3891	32/18639	0.4375	2.09574980724749	0.00295625988845366	0.0618504998537415
GO:0004659	prenyltransferase activity	9/3891	17/18639	0.529411764705882	2.53603338019865	0.0035046216899595	0.0719875638681905
GO:0008171	O-methyltransferase activity	11/3891	23/18639	0.478260869565217	2.29100600046931	0.00354830411896981	0.0719875638681905
GO:0043024	ribosomal small subunit binding	10/3891	20/18639	0.5	2.39514263685428	0.00360224836647093	0.0719912024284265
GO:0004518	nuclease activity	60/3891	209/18639	0.287081339712919	1.37520151398332	0.00428215306056255	0.0843206315896067
GO:0005044	scavenger receptor activity	12/3891	27/18639	0.444444444444444	2.1290156772038	0.00496875788673663	0.0946398135092671
GO:0004526	ribonuclease P activity	7/3891	12/18639	0.583333333333333	2.79433307632999	0.00501824253857951	0.0946398135092671
GO:0005049	nuclear export signal receptor activity	7/3891	12/18639	0.583333333333333	2.79433307632999	0.00501824253857951	0.0946398135092671
GO:0016830	carbon-carbon lyase activity	19/3891	51/18639	0.372549019607843	1.78461608236201	0.00528849962941497	0.09835140283037
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	8/3891	15/18639	0.533333333333333	2.55481881264456	0.00557784839502767	0.0997056842913038
GO:0016854	racemase and epimerase activity	9/3891	18/18639	0.5	2.39514263685428	0.0057218576617668	0.0997056842913038
GO:0015035	protein-disulfide reductase activity	14/3891	34/18639	0.411764705882353	1.97247040682117	0.00573363531772247	0.0997056842913038
GO:0016831	carboxy-lyase activity	14/3891	34/18639	0.411764705882353	1.97247040682117	0.00573363531772247	0.0997056842913038
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	14/3891	34/18639	0.411764705882353	1.97247040682117	0.00573363531772247	0.0997056842913038
GO:0004540	RNA nuclease activity	37/3891	121/18639	0.305785123966942	1.46479797625799	0.00757408896720691	0.130021860603719
GO:0051020	GTPase binding	84/3891	315/18639	0.266666666666667	1.27740940632228	0.00773010373084808	0.131020365767159
GO:0008239	dipeptidyl-peptidase activity	6/3891	10/18639	0.6	2.87417116422513	0.00793065749458825	0.131100622040169
GO:0047429	nucleoside triphosphate diphosphatase activity	6/3891	10/18639	0.6	2.87417116422513	0.00793065749458825	0.131100622040169
GO:0003756	protein disulfide isomerase activity	9/3891	19/18639	0.473684210526316	2.26908249807247	0.00888085630734128	0.14052185633966
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	9/3891	19/18639	0.473684210526316	2.26908249807247	0.00888085630734128	0.14052185633966
GO:0019104	DNA N-glycosylase activity	7/3891	13/18639	0.538461538461538	2.57938437815076	0.00892697808604521	0.14052185633966
GO:0035325	Toll-like receptor binding	7/3891	13/18639	0.538461538461538	2.57938437815076	0.00892697808604521	0.14052185633966
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	15/3891	39/18639	0.384615384615385	1.84241741296483	0.00902530219955997	0.14052185633966
GO:0022804	active transmembrane transporter activity	116/3891	457/18639	0.25382932166302	1.2159148615978	0.0107594305197352	0.16291624939524
GO:0043178	alcohol binding	29/3891	92/18639	0.315217391304348	1.50998122758205	0.0108019823273076	0.16291624939524
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	91/3891	349/18639	0.260744985673352	1.24904286506441	0.0108286379359047	0.16291624939524
GO:0003713	transcription coactivator activity	69/3891	256/18639	0.26953125	1.29113157767926	0.0114437633628267	0.17025776825361
GO:0015036	disulfide oxidoreductase activity	15/3891	40/18639	0.375	1.79635697764071	0.0117074772350241	0.170394695844536
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	15/3891	40/18639	0.375	1.79635697764071	0.0117074772350241	0.170394695844536
GO:0004602	glutathione peroxidase activity	10/3891	23/18639	0.434782608695652	2.08273272769937	0.0120880919573464	0.174042528289106
GO:0031267	small GTPase binding	75/3891	283/18639	0.265017667844523	1.2695102315482	0.0131345476197878	0.184108557619562
GO:0000339	RNA cap binding	9/3891	20/18639	0.45	2.15562837316885	0.0131997173498715	0.184108557619562
GO:0016004	phospholipase activator activity	9/3891	20/18639	0.45	2.15562837316885	0.0131997173498715	0.184108557619562
GO:0004550	nucleoside diphosphate kinase activity	8/3891	17/18639	0.470588235294118	2.25425189350991	0.0141379897731415	0.190756375420514
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	8/3891	17/18639	0.470588235294118	2.25425189350991	0.0141379897731415	0.190756375420514
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	6/3891	11/18639	0.545454545454545	2.6128828765683	0.0143886437023689	0.190756375420514
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	6/3891	11/18639	0.545454545454545	2.6128828765683	0.0143886437023689	0.190756375420514
GO:0140031	phosphorylation-dependent protein binding	6/3891	11/18639	0.545454545454545	2.6128828765683	0.0143886437023689	0.190756375420514
GO:0032036	myosin heavy chain binding	7/3891	14/18639	0.5	2.39514263685428	0.0146723534655425	0.191683655278096
GO:0051087	protein-folding chaperone binding	39/3891	134/18639	0.291044776119403	1.39418750503458	0.0147463360352309	0.191683655278096
GO:0061650	ubiquitin-like protein conjugating enzyme activity	15/3891	41/18639	0.365853658536585	1.7525433928202	0.0149739607967656	0.191683655278096
GO:0004364	glutathione transferase activity	11/3891	27/18639	0.407407407407407	1.95159770410349	0.0150312052309187	0.191683655278096
GO:0051539	4 iron, 4 sulfur cluster binding	16/3891	45/18639	0.355555555555556	1.70321254176304	0.0163291479885924	0.206271029780427
GO:0001098	basal transcription machinery binding	20/3891	60/18639	0.333333333333333	1.59676175790285	0.0167400208085462	0.207545257987439
GO:0001099	basal RNA polymerase II transcription machinery binding	20/3891	60/18639	0.333333333333333	1.59676175790285	0.0167400208085462	0.207545257987439
GO:0048027	mRNA 5'-UTR binding	10/3891	24/18639	0.416666666666667	1.99595219737857	0.0169162648730596	0.207806226284649
GO:0016763	pentosyltransferase activity	17/3891	49/18639	0.346938775510204	1.66193570720501	0.0175101343160811	0.213146089538478
GO:0016741	transferase activity, transferring one-carbon groups	58/3891	215/18639	0.269767441860465	1.29226300407022	0.0187418238832502	0.226083803420468
GO:0003924	GTPase activity	85/3891	331/18639	0.256797583081571	1.2301336805596	0.0195681611598207	0.233944355294642
GO:0016776	phosphotransferase activity, phosphate group as acceptor	14/3891	39/18639	0.358974358974359	1.71958958543384	0.0218931009252844	0.259423558751821
GO:0016846	carbon-sulfur lyase activity	7/3891	15/18639	0.466666666666667	2.23546646106399	0.0226300454022429	0.265111342298217
GO:0022884	macromolecule transmembrane transporter activity	12/3891	32/18639	0.375	1.79635697764071	0.0229965407426404	0.265111342298217
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	15/3891	43/18639	0.348837209302326	1.67102974664252	0.0235625766568511	0.265111342298217
GO:0003995	acyl-CoA dehydrogenase activity	6/3891	12/18639	0.5	2.39514263685428	0.0237590448661583	0.265111342298217
GO:0004300	enoyl-CoA hydratase activity	6/3891	12/18639	0.5	2.39514263685428	0.0237590448661583	0.265111342298217
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	6/3891	12/18639	0.5	2.39514263685428	0.0237590448661583	0.265111342298217
GO:0097371	MDM2/MDM4 family protein binding	6/3891	12/18639	0.5	2.39514263685428	0.0237590448661583	0.265111342298217
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	35/3891	122/18639	0.286885245901639	1.37426216868688	0.0247963022903276	0.27403787431839
GO:0005504	fatty acid binding	16/3891	47/18639	0.340425531914894	1.63073541232632	0.0249683500125792	0.27403787431839
GO:0005507	copper ion binding	20/3891	63/18639	0.317460317460317	1.520725483717	0.0285098166421083	0.308190261815499
GO:0017124	SH3 domain binding	33/3891	115/18639	0.28695652173913	1.37460360028159	0.0285403976587915	0.308190261815499
GO:0019955	cytokine binding	40/3891	144/18639	0.277777777777778	1.33063479825238	0.0289492121583547	0.310103960640296
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	12/3891	33/18639	0.363636363636364	1.7419219177122	0.0294472206464224	0.312935146393331
GO:0038187	pattern recognition receptor activity	16/3891	48/18639	0.333333333333333	1.59676175790285	0.0303937007193757	0.319987888107685
GO:0050750	low-density lipoprotein particle receptor binding	10/3891	26/18639	0.384615384615385	1.84241741296483	0.0305926748504267	0.319987888107685
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	36/3891	128/18639	0.28125	1.34726773323053	0.0308278099819951	0.319987888107685
GO:0017070	U6 snRNA binding	7/3891	16/18639	0.4375	2.09574980724749	0.0331269292749309	0.341207371531788
GO:0043130	ubiquitin binding	29/3891	100/18639	0.29	1.38918272937548	0.0335365570963916	0.342789694290598
GO:0140597	protein carrier chaperone	50/3891	188/18639	0.265957446808511	1.27401204087994	0.0348962582750627	0.343200732122512
GO:0017134	fibroblast growth factor binding	9/3891	23/18639	0.391304347826087	1.87445945492944	0.0352414322455777	0.343200732122512
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	45/3891	167/18639	0.269461077844311	1.29079543303524	0.035496860774117	0.343200732122512
GO:0003697	single-stranded DNA binding	34/3891	121/18639	0.28099173553719	1.34603057277761	0.0355075874140541	0.343200732122512
GO:0005035	death receptor activity	6/3891	13/18639	0.461538461538462	2.2109008955578	0.0364722449633981	0.343200732122512
GO:0005338	nucleotide-sugar transmembrane transporter activity	6/3891	13/18639	0.461538461538462	2.2109008955578	0.0364722449633981	0.343200732122512
GO:0005542	folic acid binding	6/3891	13/18639	0.461538461538462	2.2109008955578	0.0364722449633981	0.343200732122512
GO:0070700	BMP receptor binding	6/3891	13/18639	0.461538461538462	2.2109008955578	0.0364722449633981	0.343200732122512
GO:0140296	general transcription initiation factor binding	17/3891	53/18639	0.320754716981132	1.53650659722727	0.037616153133398	0.343200732122512
GO:0016798	hydrolase activity, acting on glycosyl bonds	36/3891	130/18639	0.276923076923077	1.32654053733468	0.0383096753842088	0.343200732122512
GO:0001094	TFIID-class transcription factor complex binding	5/3891	10/18639	0.5	2.39514263685428	0.038889439034667	0.343200732122512
GO:0005031	tumor necrosis factor receptor activity	5/3891	10/18639	0.5	2.39514263685428	0.038889439034667	0.343200732122512
GO:0005528	FK506 binding	5/3891	10/18639	0.5	2.39514263685428	0.038889439034667	0.343200732122512
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	5/3891	10/18639	0.5	2.39514263685428	0.038889439034667	0.343200732122512
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	5/3891	10/18639	0.5	2.39514263685428	0.038889439034667	0.343200732122512
GO:0043422	protein kinase B binding	5/3891	10/18639	0.5	2.39514263685428	0.038889439034667	0.343200732122512
GO:0097177	mitochondrial ribosome binding	5/3891	10/18639	0.5	2.39514263685428	0.038889439034667	0.343200732122512
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	5/3891	10/18639	0.5	2.39514263685428	0.038889439034667	0.343200732122512
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	5/3891	10/18639	0.5	2.39514263685428	0.038889439034667	0.343200732122512
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	5/3891	10/18639	0.5	2.39514263685428	0.038889439034667	0.343200732122512
GO:0005201	extracellular matrix structural constituent	45/3891	168/18639	0.267857142857143	1.28311212688622	0.038959306409725	0.343200732122512
GO:0008320	protein transmembrane transporter activity	10/3891	27/18639	0.37037037037037	1.77417973100317	0.0397464805089609	0.347846649682998
GO:0048487	beta-tubulin binding	14/3891	42/18639	0.333333333333333	1.59676175790285	0.0412636185222233	0.358779124683487
GO:0030695	GTPase regulator activity	118/3891	489/18639	0.241308793456033	1.15593795970881	0.042784579215607	0.359279140428668
GO:0070325	lipoprotein particle receptor binding	11/3891	31/18639	0.354838709677419	1.69977864550949	0.0432976346566478	0.359279140428668
GO:0015485	cholesterol binding	17/3891	54/18639	0.314814814814815	1.50805277135269	0.0445577407747023	0.359279140428668
GO:0050660	flavin adenine dinucleotide binding	25/3891	86/18639	0.290697674418605	1.39252478886877	0.0447255772300123	0.359279140428668
GO:0060589	nucleoside-triphosphatase regulator activity	118/3891	490/18639	0.240816326530612	1.15357890264818	0.0450523852849192	0.359279140428668
GO:0008168	methyltransferase activity	53/3891	204/18639	0.259803921568627	1.24453489954193	0.0456023382836932	0.359279140428668
GO:0000287	magnesium ion binding	59/3891	230/18639	0.256521739130435	1.22881230934263	0.0459520153121132	0.359279140428668
GO:0019838	growth factor binding	37/3891	136/18639	0.272058823529412	1.30323937593542	0.0461464756020392	0.359279140428668
GO:0044325	transmembrane transporter binding	37/3891	136/18639	0.272058823529412	1.30323937593542	0.0461464756020392	0.359279140428668
GO:0001091	RNA polymerase II general transcription initiation factor binding	9/3891	24/18639	0.375	1.79635697764071	0.0462365326690888	0.359279140428668
GO:0042625	ATPase-coupled ion transmembrane transporter activity	9/3891	24/18639	0.375	1.79635697764071	0.0462365326690888	0.359279140428668
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	9/3891	24/18639	0.375	1.79635697764071	0.0462365326690888	0.359279140428668
GO:0046961	proton-transporting ATPase activity, rotational mechanism	9/3891	24/18639	0.375	1.79635697764071	0.0462365326690888	0.359279140428668
GO:0060229	lipase activator activity	9/3891	24/18639	0.375	1.79635697764071	0.0462365326690888	0.359279140428668
GO:0003712	transcription coregulator activity	119/3891	495/18639	0.24040404040404	1.15160393448751	0.0462826293312791	0.359279140428668
GO:0004549	tRNA-specific ribonuclease activity	7/3891	17/18639	0.411764705882353	1.97247040682117	0.0464191869261834	0.359279140428668
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	7/3891	17/18639	0.411764705882353	1.97247040682117	0.0464191869261834	0.359279140428668
GO:0015278	intracellularly gated calcium channel activity	7/3891	17/18639	0.411764705882353	1.97247040682117	0.0464191869261834	0.359279140428668
GO:0016018	cyclosporin A binding	7/3891	17/18639	0.411764705882353	1.97247040682117	0.0464191869261834	0.359279140428668
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	36/3891	132/18639	0.272727272727273	1.30644143828415	0.0470909491767487	0.362383798549807
GO:0032182	ubiquitin-like protein binding	33/3891	120/18639	0.275	1.31732845026985	0.0499542318221957	0.382221236628115
GO:0019003	GDP binding	22/3891	75/18639	0.293333333333333	1.40515034695451	0.0521875962123326	0.397040859819962
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	20/3891	67/18639	0.298507462686567	1.42993590259957	0.0527064722891459	0.397353241812985
GO:0030983	mismatched DNA binding	6/3891	14/18639	0.428571428571429	2.05297940301795	0.0528221635867897	0.397353241812985
GO:0072542	protein phosphatase activator activity	8/3891	21/18639	0.380952380952381	1.8248705804604	0.0538238450570904	0.398974217618967
GO:0043425	bHLH transcription factor binding	11/3891	32/18639	0.34375	1.64666056283732	0.0539315409925564	0.398974217618967
GO:0051059	NF-kappaB binding	11/3891	32/18639	0.34375	1.64666056283732	0.0539315409925564	0.398974217618967
GO:0000049	tRNA binding	23/3891	80/18639	0.2875	1.37720701619121	0.0588035588518861	0.413602932251953
GO:0000099	sulfur amino acid transmembrane transporter activity	5/3891	11/18639	0.454545454545455	2.17740239714025	0.0593067684782487	0.413602932251953
GO:0019206	nucleoside kinase activity	5/3891	11/18639	0.454545454545455	2.17740239714025	0.0593067684782487	0.413602932251953
GO:0019864	IgG binding	5/3891	11/18639	0.454545454545455	2.17740239714025	0.0593067684782487	0.413602932251953
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	5/3891	11/18639	0.454545454545455	2.17740239714025	0.0593067684782487	0.413602932251953
GO:0032404	mismatch repair complex binding	5/3891	11/18639	0.454545454545455	2.17740239714025	0.0593067684782487	0.413602932251953
GO:0034511	U3 snoRNA binding	5/3891	11/18639	0.454545454545455	2.17740239714025	0.0593067684782487	0.413602932251953
GO:0035252	UDP-xylosyltransferase activity	5/3891	11/18639	0.454545454545455	2.17740239714025	0.0593067684782487	0.413602932251953
GO:0042285	xylosyltransferase activity	5/3891	11/18639	0.454545454545455	2.17740239714025	0.0593067684782487	0.413602932251953
GO:0048407	platelet-derived growth factor binding	5/3891	11/18639	0.454545454545455	2.17740239714025	0.0593067684782487	0.413602932251953
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	5/3891	11/18639	0.454545454545455	2.17740239714025	0.0593067684782487	0.413602932251953
GO:0140030	modification-dependent protein binding	45/3891	173/18639	0.260115606936416	1.24602796136928	0.0602422959249615	0.41795043649494
GO:0005080	protein kinase C binding	16/3891	52/18639	0.307692307692308	1.47393393037186	0.0608595122196911	0.420056117846219
GO:0003746	translation elongation factor activity	7/3891	18/18639	0.388888888888889	1.86288871755333	0.0626771905850558	0.428187541803009
GO:0031690	adrenergic receptor binding	7/3891	18/18639	0.388888888888889	1.86288871755333	0.0626771905850558	0.428187541803009
GO:0042826	histone deacetylase binding	34/3891	127/18639	0.267716535433071	1.28243857721331	0.0659260008457405	0.448096015900744
GO:0019213	deacetylase activity	12/3891	37/18639	0.324324324324324	1.55360603471629	0.0681996469224284	0.459214410496007
GO:0043539	protein serine/threonine kinase activator activity	21/3891	73/18639	0.287671232876712	1.3780272705189	0.0683207170027668	0.459214410496007
GO:0140318	protein transporter activity	13/3891	41/18639	0.317073170731707	1.51887094044418	0.0695588115401299	0.459214410496007
GO:0034062	5'-3' RNA polymerase activity	8/3891	22/18639	0.363636363636364	1.7419219177122	0.0696195110759443	0.459214410496007
GO:0097747	RNA polymerase activity	8/3891	22/18639	0.363636363636364	1.7419219177122	0.0696195110759443	0.459214410496007
GO:0140517	protein-RNA adaptor activity	8/3891	22/18639	0.363636363636364	1.7419219177122	0.0696195110759443	0.459214410496007
GO:0141050	histone H3K deacetylase activity	6/3891	15/18639	0.4	1.91611410948342	0.0729502423764877	0.476489631912766
GO:0141051	histone H4K deacetylase activity	6/3891	15/18639	0.4	1.91611410948342	0.0729502423764877	0.476489631912766
GO:0045296	cadherin binding	81/3891	334/18639	0.24251497005988	1.16171588973172	0.0734269929757269	0.477275454342225
GO:0030507	spectrin binding	9/3891	26/18639	0.346153846153846	1.65817567166835	0.0744823669478754	0.479480237226948
GO:0097602	cullin family protein binding	9/3891	26/18639	0.346153846153846	1.65817567166835	0.0744823669478754	0.479480237226948
GO:0016922	nuclear receptor binding	36/3891	137/18639	0.262773722627737	1.25876109382123	0.0754289603824006	0.483250612210691
GO:0003684	damaged DNA binding	21/3891	74/18639	0.283783783783784	1.35940528037675	0.0773374238859425	0.493118145634653
GO:0050145	nucleoside monophosphate kinase activity	7/3891	19/18639	0.368421052631579	1.76484194294526	0.0819775127955281	0.508782261960409
GO:0070003	threonine-type peptidase activity	7/3891	19/18639	0.368421052631579	1.76484194294526	0.0819775127955281	0.508782261960409
GO:0003925	G protein activity	16/3891	54/18639	0.296296296296296	1.41934378480254	0.0820066750546771	0.508782261960409
GO:0017069	snRNA binding	16/3891	54/18639	0.296296296296296	1.41934378480254	0.0820066750546771	0.508782261960409
GO:0019902	phosphatase binding	48/3891	190/18639	0.252631578947368	1.21017733230532	0.0820567462629222	0.508782261960409
GO:0000340	RNA 7-methylguanosine cap binding	5/3891	12/18639	0.416666666666667	1.99595219737857	0.0846979996297419	0.508782261960409
GO:0000995	RNA polymerase III general transcription initiation factor activity	5/3891	12/18639	0.416666666666667	1.99595219737857	0.0846979996297419	0.508782261960409
GO:0005527	macrolide binding	5/3891	12/18639	0.416666666666667	1.99595219737857	0.0846979996297419	0.508782261960409
GO:0034452	dynactin binding	5/3891	12/18639	0.416666666666667	1.99595219737857	0.0846979996297419	0.508782261960409
GO:0097677	STAT family protein binding	5/3891	12/18639	0.416666666666667	1.99595219737857	0.0846979996297419	0.508782261960409
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	5/3891	12/18639	0.416666666666667	1.99595219737857	0.0846979996297419	0.508782261960409
GO:0141221	histone deacetylase activity, hydrolytic mechanism	5/3891	12/18639	0.416666666666667	1.99595219737857	0.0846979996297419	0.508782261960409
GO:0005085	guanyl-nucleotide exchange factor activity	57/3891	230/18639	0.247826086956522	1.18715765478864	0.0849140963131839	0.508782261960409
GO:0016835	carbon-oxygen lyase activity	22/3891	79/18639	0.278481012658228	1.33400349394416	0.0854936586565288	0.508782261960409
GO:0046332	SMAD binding	22/3891	79/18639	0.278481012658228	1.33400349394416	0.0854936586565288	0.508782261960409
GO:0044183	protein folding chaperone	21/3891	75/18639	0.28	1.3412798766384	0.0871179124256796	0.516154357247721
GO:0140101	catalytic activity, acting on a tRNA	36/3891	139/18639	0.258992805755396	1.24064942340653	0.0895487925924053	0.528219529873263
GO:0008173	RNA methyltransferase activity	19/3891	67/18639	0.283582089552239	1.35843910746959	0.0902204868996584	0.529847508590538
GO:0051117	ATPase binding	23/3891	84/18639	0.273809523809524	1.31162572970591	0.0935584190833685	0.54651715827267
GO:0140313	molecular sequestering activity	16/3891	55/18639	0.290909090909091	1.39353753416976	0.0941669934423138	0.54651715827267
GO:0005164	tumor necrosis factor receptor binding	10/3891	31/18639	0.32258064516129	1.54525331409953	0.09428339324943	0.54651715827267
GO:0030544	Hsp70 protein binding	15/3891	51/18639	0.294117647058824	1.40890743344369	0.095155321963037	0.549193862536666
GO:0015923	mannosidase activity	6/3891	16/18639	0.375	1.79635697764071	0.0968442302374219	0.554164206358581
GO:0031435	mitogen-activated protein kinase kinase kinase binding	6/3891	16/18639	0.375	1.79635697764071	0.0968442302374219	0.554164206358581
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	24/3891	89/18639	0.269662921348315	1.29176232100006	0.101510336959283	0.572360891530876
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	24/3891	89/18639	0.269662921348315	1.29176232100006	0.101510336959283	0.572360891530876
GO:0030145	manganese ion binding	19/3891	68/18639	0.279411764705882	1.33846206177151	0.101734049428191	0.572360891530876
GO:0032934	sterol binding	19/3891	68/18639	0.279411764705882	1.33846206177151	0.101734049428191	0.572360891530876
GO:0008238	exopeptidase activity	27/3891	102/18639	0.264705882352941	1.26801669009932	0.103827837249705	0.577107080849132
GO:0016874	ligase activity	42/3891	167/18639	0.251497005988024	1.20474240416622	0.103849054966834	0.577107080849132
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	7/3891	20/18639	0.35	1.676599845798	0.104301653148237	0.577107080849132
GO:0042288	MHC class I protein binding	7/3891	20/18639	0.35	1.676599845798	0.104301653148237	0.577107080849132
GO:0030971	receptor tyrosine kinase binding	22/3891	81/18639	0.271604938271605	1.30106513606899	0.106482998830897	0.583882160323089
GO:0004725	protein tyrosine phosphatase activity	26/3891	98/18639	0.26530612244898	1.27089201139207	0.106547257821494	0.583882160323089
GO:0033218	amide binding	60/3891	247/18639	0.242914979757085	1.16363205029358	0.106834301179355	0.583882160323089
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	8/3891	24/18639	0.333333333333333	1.59676175790285	0.108813463343665	0.589883511810397
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	8/3891	24/18639	0.333333333333333	1.59676175790285	0.108813463343665	0.589883511810397
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	14/3891	48/18639	0.291666666666667	1.397166538165	0.110524320762897	0.593704826025562
GO:0030020	extracellular matrix structural constituent conferring tensile strength	13/3891	44/18639	0.295454545454545	1.41531155814117	0.111727260075681	0.593704826025562
GO:0140793	histone H2AXY142 phosphatase activity	24/3891	90/18639	0.266666666666667	1.27740940632228	0.112188251400627	0.593704826025562
GO:0120015	sterol transfer activity	10/3891	32/18639	0.3125	1.49696414803392	0.112625144275282	0.593704826025562
GO:0140142	nucleocytoplasmic carrier activity	10/3891	32/18639	0.3125	1.49696414803392	0.112625144275282	0.593704826025562
GO:0035591	signaling adaptor activity	33/3891	129/18639	0.255813953488372	1.22542181420451	0.114508904949166	0.593704826025562
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	5/3891	13/18639	0.384615384615385	1.84241741296483	0.114839096296207	0.593704826025562
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	5/3891	13/18639	0.384615384615385	1.84241741296483	0.114839096296207	0.593704826025562
GO:0017154	semaphorin receptor activity	5/3891	13/18639	0.384615384615385	1.84241741296483	0.114839096296207	0.593704826025562
GO:0019855	calcium channel inhibitor activity	5/3891	13/18639	0.384615384615385	1.84241741296483	0.114839096296207	0.593704826025562
GO:0051011	microtubule minus-end binding	5/3891	13/18639	0.384615384615385	1.84241741296483	0.114839096296207	0.593704826025562
GO:0140852	histone ubiquitin ligase activity	5/3891	13/18639	0.384615384615385	1.84241741296483	0.114839096296207	0.593704826025562
GO:0019787	ubiquitin-like protein transferase activity	111/3891	479/18639	0.231732776617954	1.11006610726858	0.116536859420432	0.600164826015227
GO:0016836	hydro-lyase activity	17/3891	61/18639	0.278688524590164	1.33499753529583	0.119219333497009	0.611627155373543
GO:0008276	protein methyltransferase activity	25/3891	95/18639	0.263157894736842	1.26060138781804	0.120233409171037	0.614475323969536
GO:1901505	carbohydrate derivative transmembrane transporter activity	15/3891	53/18639	0.283018867924528	1.35574111520054	0.124117581545403	0.616677934387028
GO:0048029	monosaccharide binding	20/3891	74/18639	0.27027027027027	1.29467169559691	0.124243848515294	0.616677934387028
GO:0016805	dipeptidase activity	6/3891	17/18639	0.352941176470588	1.69068892013243	0.124348799316279	0.616677934387028
GO:0030169	low-density lipoprotein particle binding	6/3891	17/18639	0.352941176470588	1.69068892013243	0.124348799316279	0.616677934387028
GO:0048038	quinone binding	6/3891	17/18639	0.352941176470588	1.69068892013243	0.124348799316279	0.616677934387028
GO:0070402	NADPH binding	6/3891	17/18639	0.352941176470588	1.69068892013243	0.124348799316279	0.616677934387028
GO:0070403	NAD+ binding	6/3891	17/18639	0.352941176470588	1.69068892013243	0.124348799316279	0.616677934387028
GO:1901567	fatty acid derivative binding	6/3891	17/18639	0.352941176470588	1.69068892013243	0.124348799316279	0.616677934387028
GO:0140312	cargo adaptor activity	7/3891	21/18639	0.333333333333333	1.59676175790285	0.129540557193811	0.629202967651853
GO:0023023	MHC protein complex binding	11/3891	37/18639	0.297297297297297	1.4241388651566	0.131859887649044	0.629202967651853
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	8/3891	25/18639	0.32	1.53289128758674	0.132118725518644	0.629202967651853
GO:0017025	TBP-class protein binding	8/3891	25/18639	0.32	1.53289128758674	0.132118725518644	0.629202967651853
GO:0019211	phosphatase activator activity	8/3891	25/18639	0.32	1.53289128758674	0.132118725518644	0.629202967651853
GO:0003785	actin monomer binding	9/3891	29/18639	0.310344827586207	1.48664025735783	0.133025401218383	0.629202967651853
GO:0051861	glycolipid binding	9/3891	29/18639	0.310344827586207	1.48664025735783	0.133025401218383	0.629202967651853
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	4/3891	10/18639	0.4	1.91611410948342	0.136742392521799	0.629202967651853
GO:0008641	ubiquitin-like modifier activating enzyme activity	4/3891	10/18639	0.4	1.91611410948342	0.136742392521799	0.629202967651853
GO:0015924	mannosyl-oligosaccharide mannosidase activity	4/3891	10/18639	0.4	1.91611410948342	0.136742392521799	0.629202967651853
GO:0016303	1-phosphatidylinositol-3-kinase activity	4/3891	10/18639	0.4	1.91611410948342	0.136742392521799	0.629202967651853
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	4/3891	10/18639	0.4	1.91611410948342	0.136742392521799	0.629202967651853
GO:0016783	sulfurtransferase activity	4/3891	10/18639	0.4	1.91611410948342	0.136742392521799	0.629202967651853
GO:0030957	Tat protein binding	4/3891	10/18639	0.4	1.91611410948342	0.136742392521799	0.629202967651853
GO:0031996	thioesterase binding	4/3891	10/18639	0.4	1.91611410948342	0.136742392521799	0.629202967651853
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	4/3891	10/18639	0.4	1.91611410948342	0.136742392521799	0.629202967651853
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	4/3891	10/18639	0.4	1.91611410948342	0.136742392521799	0.629202967651853
GO:0043295	glutathione binding	4/3891	10/18639	0.4	1.91611410948342	0.136742392521799	0.629202967651853
GO:0050815	phosphoserine residue binding	4/3891	10/18639	0.4	1.91611410948342	0.136742392521799	0.629202967651853
GO:0070513	death domain binding	4/3891	10/18639	0.4	1.91611410948342	0.136742392521799	0.629202967651853
GO:1905394	retromer complex binding	4/3891	10/18639	0.4	1.91611410948342	0.136742392521799	0.629202967651853
GO:0032813	tumor necrosis factor receptor superfamily binding	14/3891	50/18639	0.28	1.3412798766384	0.143516737817421	0.658112712114816
GO:0042054	histone methyltransferase activity	18/3891	67/18639	0.26865671641791	1.28694231233961	0.145430887953085	0.664614194434065
GO:0005313	L-glutamate transmembrane transporter activity	5/3891	14/18639	0.357142857142857	1.71081616918163	0.149292947801438	0.677638159681783
GO:0019763	immunoglobulin receptor activity	5/3891	14/18639	0.357142857142857	1.71081616918163	0.149292947801438	0.677638159681783
GO:0070063	RNA polymerase binding	16/3891	59/18639	0.271186440677966	1.2990604132091	0.153479554775483	0.681312938254559
GO:0030332	cyclin binding	10/3891	34/18639	0.294117647058824	1.40890743344369	0.154798826273823	0.681312938254559
GO:0008308	voltage-gated monoatomic anion channel activity	6/3891	18/18639	0.333333333333333	1.59676175790285	0.15518460368189	0.681312938254559
GO:0015172	acidic amino acid transmembrane transporter activity	6/3891	18/18639	0.333333333333333	1.59676175790285	0.15518460368189	0.681312938254559
GO:0035615	clathrin adaptor activity	6/3891	18/18639	0.333333333333333	1.59676175790285	0.15518460368189	0.681312938254559
GO:0070064	proline-rich region binding	6/3891	18/18639	0.333333333333333	1.59676175790285	0.15518460368189	0.681312938254559
GO:1990381	ubiquitin-specific protease binding	6/3891	18/18639	0.333333333333333	1.59676175790285	0.15518460368189	0.681312938254559
GO:0005518	collagen binding	19/3891	72/18639	0.263888888888889	1.26410305833976	0.156532462104678	0.681312938254559
GO:0051015	actin filament binding	50/3891	209/18639	0.239234449760766	1.14600126165277	0.15745593436134	0.681312938254559
GO:0004407	histone deacetylase activity	7/3891	22/18639	0.318181818181818	1.52418167799818	0.157503712048815	0.681312938254559
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	7/3891	22/18639	0.318181818181818	1.52418167799818	0.157503712048815	0.681312938254559
GO:0033558	protein lysine deacetylase activity	7/3891	22/18639	0.318181818181818	1.52418167799818	0.157503712048815	0.681312938254559
GO:0008198	ferrous iron binding	8/3891	26/18639	0.307692307692308	1.47393393037186	0.15773488488343	0.681312938254559
GO:0070006	metalloaminopeptidase activity	8/3891	26/18639	0.307692307692308	1.47393393037186	0.15773488488343	0.681312938254559
GO:0070412	R-SMAD binding	8/3891	26/18639	0.307692307692308	1.47393393037186	0.15773488488343	0.681312938254559
GO:0004536	DNA nuclease activity	17/3891	64/18639	0.265625	1.27241952582884	0.165946447770317	0.714476828181527
GO:0019207	kinase regulator activity	67/3891	287/18639	0.233449477351916	1.11828959351384	0.167183541048721	0.717496030334096
GO:1990782	protein tyrosine kinase binding	29/3891	117/18639	0.247863247863248	1.18733566613289	0.175298591560117	0.727114158246811
GO:0019212	phosphatase inhibitor activity	15/3891	56/18639	0.267857142857143	1.28311212688622	0.175991768164294	0.727114158246811
GO:0005154	epidermal growth factor receptor binding	10/3891	35/18639	0.285714285714286	1.3686529353453	0.178453197190657	0.727114158246811
GO:0043015	gamma-tubulin binding	10/3891	35/18639	0.285714285714286	1.3686529353453	0.178453197190657	0.727114158246811
GO:0061631	ubiquitin conjugating enzyme activity	10/3891	35/18639	0.285714285714286	1.3686529353453	0.178453197190657	0.727114158246811
GO:0035091	phosphatidylinositol binding	66/3891	284/18639	0.232394366197183	1.1132353100872	0.179675238755187	0.727114158246811
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	4/3891	11/18639	0.363636363636364	1.7419219177122	0.180991320546685	0.727114158246811
GO:0005225	volume-sensitive anion channel activity	4/3891	11/18639	0.363636363636364	1.7419219177122	0.180991320546685	0.727114158246811
GO:0005536	D-glucose binding	4/3891	11/18639	0.363636363636364	1.7419219177122	0.180991320546685	0.727114158246811
GO:0008172	S-methyltransferase activity	4/3891	11/18639	0.363636363636364	1.7419219177122	0.180991320546685	0.727114158246811
GO:0010854	adenylate cyclase regulator activity	4/3891	11/18639	0.363636363636364	1.7419219177122	0.180991320546685	0.727114158246811
GO:0015217	ADP transmembrane transporter activity	4/3891	11/18639	0.363636363636364	1.7419219177122	0.180991320546685	0.727114158246811
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	4/3891	11/18639	0.363636363636364	1.7419219177122	0.180991320546685	0.727114158246811
GO:0034713	type I transforming growth factor beta receptor binding	4/3891	11/18639	0.363636363636364	1.7419219177122	0.180991320546685	0.727114158246811
GO:0050786	RAGE receptor binding	4/3891	11/18639	0.363636363636364	1.7419219177122	0.180991320546685	0.727114158246811
GO:0097493	structural molecule activity conferring elasticity	4/3891	11/18639	0.363636363636364	1.7419219177122	0.180991320546685	0.727114158246811
GO:1900750	oligopeptide binding	4/3891	11/18639	0.363636363636364	1.7419219177122	0.180991320546685	0.727114158246811
GO:0072341	modified amino acid binding	23/3891	91/18639	0.252747252747253	1.21073144280546	0.18120755763277	0.727114158246811
GO:0038024	cargo receptor activity	17/3891	65/18639	0.261538461538462	1.25284384081608	0.183393291146789	0.727114158246811
GO:0023026	MHC class II protein complex binding	8/3891	27/18639	0.296296296296296	1.41934378480254	0.185475758448103	0.727114158246811
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	8/3891	27/18639	0.296296296296296	1.41934378480254	0.185475758448103	0.727114158246811
GO:0035255	ionotropic glutamate receptor binding	8/3891	27/18639	0.296296296296296	1.41934378480254	0.185475758448103	0.727114158246811
GO:0016755	aminoacyltransferase activity	112/3891	496/18639	0.225806451612903	1.08167731986967	0.185867278830292	0.727114158246811
GO:0000774	adenyl-nucleotide exchange factor activity	5/3891	15/18639	0.333333333333333	1.59676175790285	0.187464300513913	0.727114158246811
GO:0004559	alpha-mannosidase activity	5/3891	15/18639	0.333333333333333	1.59676175790285	0.187464300513913	0.727114158246811
GO:0005041	low-density lipoprotein particle receptor activity	5/3891	15/18639	0.333333333333333	1.59676175790285	0.187464300513913	0.727114158246811
GO:0005523	tropomyosin binding	5/3891	15/18639	0.333333333333333	1.59676175790285	0.187464300513913	0.727114158246811
GO:0050700	CARD domain binding	5/3891	15/18639	0.333333333333333	1.59676175790285	0.187464300513913	0.727114158246811
GO:0050780	dopamine receptor binding	5/3891	15/18639	0.333333333333333	1.59676175790285	0.187464300513913	0.727114158246811
GO:0031681	G-protein beta-subunit binding	7/3891	23/18639	0.304347826086957	1.45791290938956	0.187931498247361	0.727114158246811
GO:0042171	lysophosphatidic acid acyltransferase activity	7/3891	23/18639	0.304347826086957	1.45791290938956	0.187931498247361	0.727114158246811
GO:0071617	lysophospholipid acyltransferase activity	7/3891	23/18639	0.304347826086957	1.45791290938956	0.187931498247361	0.727114158246811
GO:0140102	catalytic activity, acting on a rRNA	7/3891	23/18639	0.304347826086957	1.45791290938956	0.187931498247361	0.727114158246811
GO:0008301	DNA binding, bending	6/3891	19/18639	0.315789473684211	1.51272166538165	0.188972491783289	0.727114158246811
GO:0120227	acyl-CoA binding	6/3891	19/18639	0.315789473684211	1.51272166538165	0.188972491783289	0.727114158246811
GO:0035064	methylated histone binding	19/3891	74/18639	0.256756756756757	1.22993811081706	0.188973657259067	0.727114158246811
GO:0002020	protease binding	33/3891	136/18639	0.242647058823529	1.16234863259105	0.190697701922414	0.731645337748173
GO:0004177	aminopeptidase activity	11/3891	40/18639	0.275	1.31732845026985	0.197895428685017	0.754934413131733
GO:0140662	ATP-dependent protein folding chaperone	11/3891	40/18639	0.275	1.31732845026985	0.197895428685017	0.754934413131733
GO:0008235	metalloexopeptidase activity	17/3891	66/18639	0.257575757575758	1.23386135837948	0.201709940540629	0.765324615107371
GO:0005246	calcium channel regulator activity	14/3891	53/18639	0.264150943396226	1.26535837418717	0.201762202489098	0.765324615107371
GO:0000993	RNA polymerase II complex binding	10/3891	36/18639	0.277777777777778	1.33063479825238	0.20365293836563	0.770314362914066
GO:0019887	protein kinase regulator activity	59/3891	255/18639	0.231372549019608	1.10834051430904	0.205502257506174	0.775119782537371
GO:0071813	lipoprotein particle binding	9/3891	32/18639	0.28125	1.34726773323053	0.209428898720705	0.776423436979425
GO:0071814	protein-lipid complex binding	9/3891	32/18639	0.28125	1.34726773323053	0.209428898720705	0.776423436979425
GO:0003689	DNA clamp loader activity	38/3891	160/18639	0.2375	1.13769275250578	0.209673463290748	0.776423436979425
GO:0000510	H3-H4 histone complex chaperone activity	36/3891	151/18639	0.23841059602649	1.14205476724178	0.20990685898921	0.776423436979425
GO:0140584	chromatin extrusion motor activity	36/3891	151/18639	0.23841059602649	1.14205476724178	0.20990685898921	0.776423436979425
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	36/3891	151/18639	0.23841059602649	1.14205476724178	0.20990685898921	0.776423436979425
GO:0140849	ATP-dependent H2AZ histone chaperone activity	36/3891	151/18639	0.23841059602649	1.14205476724178	0.20990685898921	0.776423436979425
GO:0004842	ubiquitin-protein transferase activity	101/3891	449/18639	0.224944320712695	1.0775474669144	0.21196983511713	0.77674875079976
GO:0046875	ephrin receptor binding	8/3891	28/18639	0.285714285714286	1.3686529353453	0.215112750232489	0.77674875079976
GO:0004715	non-membrane spanning protein tyrosine kinase activity	12/3891	45/18639	0.266666666666667	1.27740940632228	0.215384929016189	0.77674875079976
GO:0050431	transforming growth factor beta binding	7/3891	24/18639	0.291666666666667	1.397166538165	0.220509512619471	0.77674875079976
GO:0008170	N-methyltransferase activity	24/3891	98/18639	0.244897959183673	1.17313108743883	0.221160854381031	0.77674875079976
GO:0015616	DNA translocase activity	36/3891	152/18639	0.236842105263158	1.13454124903624	0.222574896110642	0.77674875079976
GO:0140674	ATP-dependent histone chaperone activity	36/3891	152/18639	0.236842105263158	1.13454124903624	0.222574896110642	0.77674875079976
GO:0001530	lipopolysaccharide binding	11/3891	41/18639	0.268292682926829	1.28519848806815	0.222653674952978	0.77674875079976
GO:0017080	sodium channel regulator activity	11/3891	41/18639	0.268292682926829	1.28519848806815	0.222653674952978	0.77674875079976
GO:0042169	SH2 domain binding	11/3891	41/18639	0.268292682926829	1.28519848806815	0.222653674952978	0.77674875079976
GO:0042287	MHC protein binding	11/3891	41/18639	0.268292682926829	1.28519848806815	0.222653674952978	0.77674875079976
GO:0050661	NADP binding	14/3891	54/18639	0.259259259259259	1.24192581170222	0.223269043945639	0.77674875079976
GO:0140034	methylation-dependent protein binding	19/3891	76/18639	0.25	1.19757131842714	0.224455193028883	0.77674875079976
GO:0140939	histone H4 methyltransferase activity	6/3891	20/18639	0.3	1.43708558211257	0.225259994055454	0.77674875079976
GO:0042578	phosphoric ester hydrolase activity	82/3891	363/18639	0.225895316804408	1.08210300948788	0.226148357040256	0.77674875079976
GO:0004721	phosphoprotein phosphatase activity	41/3891	175/18639	0.234285714285714	1.12229540698315	0.226786139618898	0.77674875079976
GO:0000062	fatty-acyl-CoA binding	5/3891	16/18639	0.3125	1.49696414803392	0.228655241548683	0.77674875079976
GO:0005159	insulin-like growth factor receptor binding	5/3891	16/18639	0.3125	1.49696414803392	0.228655241548683	0.77674875079976
GO:0005521	lamin binding	5/3891	16/18639	0.3125	1.49696414803392	0.228655241548683	0.77674875079976
GO:0016722	oxidoreductase activity, acting on metal ions	5/3891	16/18639	0.3125	1.49696414803392	0.228655241548683	0.77674875079976
GO:0019841	retinol binding	5/3891	16/18639	0.3125	1.49696414803392	0.228655241548683	0.77674875079976
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	5/3891	16/18639	0.3125	1.49696414803392	0.228655241548683	0.77674875079976
GO:0097027	ubiquitin-protein transferase activator activity	5/3891	16/18639	0.3125	1.49696414803392	0.228655241548683	0.77674875079976
GO:0004000	adenosine deaminase activity	4/3891	12/18639	0.333333333333333	1.59676175790285	0.229137981005157	0.77674875079976
GO:0004875	complement receptor activity	4/3891	12/18639	0.333333333333333	1.59676175790285	0.229137981005157	0.77674875079976
GO:0005165	neurotrophin receptor binding	4/3891	12/18639	0.333333333333333	1.59676175790285	0.229137981005157	0.77674875079976
GO:0010853	cyclase activator activity	4/3891	12/18639	0.333333333333333	1.59676175790285	0.229137981005157	0.77674875079976
GO:0016273	arginine N-methyltransferase activity	4/3891	12/18639	0.333333333333333	1.59676175790285	0.229137981005157	0.77674875079976
GO:0016274	protein-arginine N-methyltransferase activity	4/3891	12/18639	0.333333333333333	1.59676175790285	0.229137981005157	0.77674875079976
GO:0016423	tRNA (guanine) methyltransferase activity	4/3891	12/18639	0.333333333333333	1.59676175790285	0.229137981005157	0.77674875079976
GO:0035497	cAMP response element binding	4/3891	12/18639	0.333333333333333	1.59676175790285	0.229137981005157	0.77674875079976
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	4/3891	12/18639	0.333333333333333	1.59676175790285	0.229137981005157	0.77674875079976
GO:1990459	transferrin receptor binding	4/3891	12/18639	0.333333333333333	1.59676175790285	0.229137981005157	0.77674875079976
GO:0043177	organic acid binding	44/3891	189/18639	0.232804232804233	1.11519868805914	0.230956686372586	0.780936876396193
GO:0140097	catalytic activity, acting on DNA	76/3891	336/18639	0.226190476190476	1.08351690714836	0.23215638525214	0.783016120535557
GO:0061775	cohesin loader activity	36/3891	153/18639	0.235294117647059	1.12712594675496	0.235600693084372	0.792636502613001
GO:0031593	polyubiquitin modification-dependent protein binding	15/3891	59/18639	0.254237288135593	1.21786913738353	0.236935325796093	0.793141003102423
GO:0045309	protein phosphorylated amino acid binding	15/3891	59/18639	0.254237288135593	1.21786913738353	0.236935325796093	0.793141003102423
GO:0019208	phosphatase regulator activity	28/3891	117/18639	0.239316239316239	1.14639305695589	0.237970783997822	0.793263243003255
GO:0140311	protein sequestering activity	9/3891	33/18639	0.272727272727273	1.30644143828415	0.238156701782904	0.793263243003255
GO:0004180	carboxypeptidase activity	12/3891	46/18639	0.260869565217391	1.24963963661962	0.239647769090046	0.796249039234669
GO:0140658	ATP-dependent chromatin remodeler activity	37/3891	158/18639	0.234177215189873	1.12177566536213	0.241645740546317	0.80090011532554
GO:0003724	RNA helicase activity	19/3891	77/18639	0.246753246753247	1.18201844416185	0.243225439840151	0.804145343076449
GO:0031072	heat shock protein binding	31/3891	131/18639	0.236641221374046	1.1335789579005	0.244717359565434	0.807085084872208
GO:0004520	DNA endonuclease activity	11/3891	42/18639	0.261904761904762	1.25459852406653	0.248567086751412	0.815763061667013
GO:0051879	Hsp90 protein binding	11/3891	42/18639	0.261904761904762	1.25459852406653	0.248567086751412	0.815763061667013
GO:0016887	ATP hydrolysis activity	93/3891	417/18639	0.223021582733813	1.06833700348896	0.251340470112639	0.82284814053991
GO:0016247	channel regulator activity	39/3891	168/18639	0.232142857142857	1.11203050996806	0.253283237312673	0.827185987223582
GO:0004709	MAP kinase kinase kinase activity	7/3891	25/18639	0.28	1.3412798766384	0.254883707603126	0.828372049710159
GO:0120020	cholesterol transfer activity	7/3891	25/18639	0.28	1.3412798766384	0.254883707603126	0.828372049710159
GO:0005109	frizzled binding	10/3891	38/18639	0.263157894736842	1.26060138781804	0.258049052617723	0.83425641234834
GO:0043531	ADP binding	10/3891	38/18639	0.263157894736842	1.26060138781804	0.258049052617723	0.83425641234834
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	15/3891	60/18639	0.25	1.19757131842714	0.258950640777921	0.83425641234834
GO:0140713	histone chaperone activity	38/3891	164/18639	0.231707317073171	1.10994414878613	0.26079826310929	0.83425641234834
GO:0031406	carboxylic acid binding	43/3891	187/18639	0.229946524064171	1.10150944796507	0.262215932724097	0.83425641234834
GO:0008094	ATP-dependent activity, acting on DNA	48/3891	210/18639	0.228571428571429	1.09492234827624	0.262730902137562	0.83425641234834
GO:0008081	phosphoric diester hydrolase activity	21/3891	87/18639	0.241379310344828	1.15627575572276	0.26311978641184	0.83425641234834
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	6/3891	21/18639	0.285714285714286	1.3686529353453	0.26354776880011	0.83425641234834
GO:0019200	carbohydrate kinase activity	6/3891	21/18639	0.285714285714286	1.3686529353453	0.26354776880011	0.83425641234834
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	6/3891	21/18639	0.285714285714286	1.3686529353453	0.26354776880011	0.83425641234834
GO:1904047	S-adenosyl-L-methionine binding	6/3891	21/18639	0.285714285714286	1.3686529353453	0.26354776880011	0.83425641234834
GO:0042393	histone binding	56/3891	247/18639	0.226720647773279	1.08605658027401	0.264475276951803	0.834538256198632
GO:0043495	protein-membrane adaptor activity	12/3891	47/18639	0.25531914893617	1.22305155924474	0.264883315074248	0.834538256198632
GO:1901681	sulfur compound binding	62/3891	275/18639	0.225454545454545	1.07999158898157	0.267489957292915	0.840772424448856
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	5/3891	17/18639	0.294117647058824	1.40890743344369	0.272116259145517	0.846823130984772
GO:0019198	transmembrane receptor protein phosphatase activity	5/3891	17/18639	0.294117647058824	1.40890743344369	0.272116259145517	0.846823130984772
GO:0036041	long-chain fatty acid binding	5/3891	17/18639	0.294117647058824	1.40890743344369	0.272116259145517	0.846823130984772
GO:0051787	misfolded protein binding	5/3891	17/18639	0.294117647058824	1.40890743344369	0.272116259145517	0.846823130984772
GO:0001540	amyloid-beta binding	20/3891	83/18639	0.240963855421687	1.15428560812254	0.272577124312499	0.846823130984772
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	8/3891	30/18639	0.266666666666667	1.27740940632228	0.27900458673276	0.851986393681591
GO:0008106	alcohol dehydrogenase (NADP+) activity	8/3891	30/18639	0.266666666666667	1.27740940632228	0.27900458673276	0.851986393681591
GO:0033612	receptor serine/threonine kinase binding	8/3891	30/18639	0.266666666666667	1.27740940632228	0.27900458673276	0.851986393681591
GO:0002161	aminoacyl-tRNA editing activity	4/3891	13/18639	0.307692307692308	1.47393393037186	0.279937485320247	0.851986393681591
GO:0005172	vascular endothelial growth factor receptor binding	4/3891	13/18639	0.307692307692308	1.47393393037186	0.279937485320247	0.851986393681591
GO:0009982	pseudouridine synthase activity	4/3891	13/18639	0.307692307692308	1.47393393037186	0.279937485320247	0.851986393681591
GO:0031432	titin binding	4/3891	13/18639	0.307692307692308	1.47393393037186	0.279937485320247	0.851986393681591
GO:0140666	annealing activity	4/3891	13/18639	0.307692307692308	1.47393393037186	0.279937485320247	0.851986393681591
GO:0141108	transporter regulator activity	39/3891	170/18639	0.229411764705882	1.09894779808608	0.279965655877446	0.851986393681591
GO:0005178	integrin binding	37/3891	161/18639	0.229813664596273	1.10087301321253	0.282496829345008	0.855982991983659
GO:0008186	ATP-dependent activity, acting on RNA	19/3891	79/18639	0.240506329113924	1.15209392658813	0.28255749249946	0.855982991983659
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	7/3891	26/18639	0.269230769230769	1.28969218907538	0.290675379131435	0.873304568268079
GO:0050681	nuclear androgen receptor binding	7/3891	26/18639	0.269230769230769	1.28969218907538	0.290675379131435	0.873304568268079
GO:0052742	phosphatidylinositol kinase activity	7/3891	26/18639	0.269230769230769	1.28969218907538	0.290675379131435	0.873304568268079
GO:0051213	dioxygenase activity	22/3891	93/18639	0.236559139784946	1.13318576367299	0.290884120573236	0.873304568268079
GO:0004527	exonuclease activity	20/3891	84/18639	0.238095238095238	1.14054411278775	0.292205803010065	0.875310000515609
GO:0016791	phosphatase activity	61/3891	273/18639	0.223443223443223	1.07035678277004	0.295764294322263	0.882636879407592
GO:1901981	phosphatidylinositol phosphate binding	42/3891	185/18639	0.227027027027027	1.0875242243014	0.295970096231523	0.882636879407592
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	30/3891	130/18639	0.230769230769231	1.1054504477789	0.299254449925746	0.888704232865629
GO:0003727	single-stranded RNA binding	21/3891	89/18639	0.235955056179775	1.13029203087505	0.301301111914958	0.888704232865629
GO:0019903	protein phosphatase binding	33/3891	144/18639	0.229166666666667	1.09777370855821	0.302721181076689	0.888704232865629
GO:0008093	cytoskeletal anchor activity	6/3891	22/18639	0.272727272727273	1.30644143828415	0.303314290081846	0.888704232865629
GO:0008649	rRNA methyltransferase activity	6/3891	22/18639	0.272727272727273	1.30644143828415	0.303314290081846	0.888704232865629
GO:0031683	G-protein beta/gamma-subunit complex binding	6/3891	22/18639	0.272727272727273	1.30644143828415	0.303314290081846	0.888704232865629
GO:0070034	telomerase RNA binding	6/3891	22/18639	0.272727272727273	1.30644143828415	0.303314290081846	0.888704232865629
GO:0140035	ubiquitin-like protein reader activity	6/3891	22/18639	0.272727272727273	1.30644143828415	0.303314290081846	0.888704232865629
GO:0140299	molecular sensor activity	17/3891	71/18639	0.23943661971831	1.14696971342318	0.304301038982034	0.889275522510199
GO:0004864	protein phosphatase inhibitor activity	13/3891	53/18639	0.245283018867925	1.1749756331738	0.304837539083033	0.889275522510199
GO:0016411	acylglycerol O-acyltransferase activity	8/3891	31/18639	0.258064516129032	1.23620265127963	0.312674758541397	0.90517069672862
GO:0070273	phosphatidylinositol-4-phosphate binding	8/3891	31/18639	0.258064516129032	1.23620265127963	0.312674758541397	0.90517069672862
GO:0004532	RNA exonuclease activity	10/3891	40/18639	0.25	1.19757131842714	0.316544906226322	0.90517069672862
GO:0071949	FAD binding	10/3891	40/18639	0.25	1.19757131842714	0.316544906226322	0.90517069672862
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	5/3891	18/18639	0.277777777777778	1.33063479825238	0.317089972785373	0.90517069672862
GO:0004706	JUN kinase kinase kinase activity	5/3891	18/18639	0.277777777777778	1.33063479825238	0.317089972785373	0.90517069672862
GO:0008409	5'-3' exonuclease activity	5/3891	18/18639	0.277777777777778	1.33063479825238	0.317089972785373	0.90517069672862
GO:0030228	lipoprotein particle receptor activity	5/3891	18/18639	0.277777777777778	1.33063479825238	0.317089972785373	0.90517069672862
GO:1901611	phosphatidylglycerol binding	5/3891	18/18639	0.277777777777778	1.33063479825238	0.317089972785373	0.90517069672862
GO:0001222	transcription corepressor binding	12/3891	49/18639	0.244897959183673	1.17313108743883	0.31772235060676	0.90517069672862
GO:0060590	ATPase regulator activity	12/3891	49/18639	0.244897959183673	1.17313108743883	0.31772235060676	0.90517069672862
GO:0140789	histone phosphatase activity	31/3891	136/18639	0.227941176470588	1.09190326091886	0.321806865693582	0.914860707353941
GO:0004386	helicase activity	35/3891	155/18639	0.225806451612903	1.08167731986967	0.329751402586852	0.919027907311743
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	13/3891	54/18639	0.240740740740741	1.15321682515206	0.330700720468061	0.919027907311743
GO:0008009	chemokine activity	11/3891	45/18639	0.244444444444444	1.17095862246209	0.33165896209178	0.919027907311743
GO:0004705	JUN kinase activity	4/3891	14/18639	0.285714285714286	1.3686529353453	0.33219530032777	0.919027907311743
GO:0005347	ATP transmembrane transporter activity	4/3891	14/18639	0.285714285714286	1.3686529353453	0.33219530032777	0.919027907311743
GO:0008174	mRNA methyltransferase activity	4/3891	14/18639	0.285714285714286	1.3686529353453	0.33219530032777	0.919027907311743
GO:0008474	palmitoyl-(protein) hydrolase activity	4/3891	14/18639	0.285714285714286	1.3686529353453	0.33219530032777	0.919027907311743
GO:0031404	chloride ion binding	4/3891	14/18639	0.285714285714286	1.3686529353453	0.33219530032777	0.919027907311743
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	4/3891	14/18639	0.285714285714286	1.3686529353453	0.33219530032777	0.919027907311743
GO:0044548	S100 protein binding	4/3891	14/18639	0.285714285714286	1.3686529353453	0.33219530032777	0.919027907311743
GO:0046030	inositol trisphosphate phosphatase activity	4/3891	14/18639	0.285714285714286	1.3686529353453	0.33219530032777	0.919027907311743
GO:0098599	palmitoyl hydrolase activity	4/3891	14/18639	0.285714285714286	1.3686529353453	0.33219530032777	0.919027907311743
GO:1901612	cardiolipin binding	4/3891	14/18639	0.285714285714286	1.3686529353453	0.33219530032777	0.919027907311743
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	21/3891	91/18639	0.230769230769231	1.1054504477789	0.341084401326475	0.921076509819411
GO:0016849	phosphorus-oxygen lyase activity	6/3891	23/18639	0.260869565217391	1.24963963661962	0.34403762837637	0.921076509819411
GO:0070577	lysine-acetylated histone binding	6/3891	23/18639	0.260869565217391	1.24963963661962	0.34403762837637	0.921076509819411
GO:0140103	catalytic activity, acting on a glycoprotein	6/3891	23/18639	0.260869565217391	1.24963963661962	0.34403762837637	0.921076509819411
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	10/3891	41/18639	0.24390243902439	1.16836226188014	0.346832400185465	0.921076509819411
GO:0016877	ligase activity, forming carbon-sulfur bonds	10/3891	41/18639	0.24390243902439	1.16836226188014	0.346832400185465	0.921076509819411
GO:0070717	poly-purine tract binding	8/3891	32/18639	0.25	1.19757131842714	0.347090045148294	0.921076509819411
GO:0003680	minor groove of adenine-thymine-rich DNA binding	3/3891	10/18639	0.3	1.43708558211257	0.348757125077253	0.921076509819411
GO:0004090	carbonyl reductase (NADPH) activity	3/3891	10/18639	0.3	1.43708558211257	0.348757125077253	0.921076509819411
GO:0005345	purine nucleobase transmembrane transporter activity	3/3891	10/18639	0.3	1.43708558211257	0.348757125077253	0.921076509819411
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	3/3891	10/18639	0.3	1.43708558211257	0.348757125077253	0.921076509819411
GO:0016175	superoxide-generating NAD(P)H oxidase activity	3/3891	10/18639	0.3	1.43708558211257	0.348757125077253	0.921076509819411
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	3/3891	10/18639	0.3	1.43708558211257	0.348757125077253	0.921076509819411
GO:0031434	mitogen-activated protein kinase kinase binding	3/3891	10/18639	0.3	1.43708558211257	0.348757125077253	0.921076509819411
GO:0032356	oxidized DNA binding	3/3891	10/18639	0.3	1.43708558211257	0.348757125077253	0.921076509819411
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	3/3891	10/18639	0.3	1.43708558211257	0.348757125077253	0.921076509819411
GO:0050308	sugar-phosphatase activity	3/3891	10/18639	0.3	1.43708558211257	0.348757125077253	0.921076509819411
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	3/3891	10/18639	0.3	1.43708558211257	0.348757125077253	0.921076509819411
GO:0140940	histone H2A methyltransferase activity	3/3891	10/18639	0.3	1.43708558211257	0.348757125077253	0.921076509819411
GO:0140999	histone H3K4 trimethyltransferase activity	3/3891	10/18639	0.3	1.43708558211257	0.348757125077253	0.921076509819411
GO:0141109	transporter activator activity	3/3891	10/18639	0.3	1.43708558211257	0.348757125077253	0.921076509819411
GO:1990259	histone H2AQ104 methyltransferase activity	3/3891	10/18639	0.3	1.43708558211257	0.348757125077253	0.921076509819411
GO:1990757	ubiquitin ligase activator activity	3/3891	10/18639	0.3	1.43708558211257	0.348757125077253	0.921076509819411
GO:0005346	purine ribonucleotide transmembrane transporter activity	5/3891	19/18639	0.263157894736842	1.26060138781804	0.362846216000404	0.947046877906743
GO:0016918	retinal binding	5/3891	19/18639	0.263157894736842	1.26060138781804	0.362846216000404	0.947046877906743
GO:0097001	ceramide binding	5/3891	19/18639	0.263157894736842	1.26060138781804	0.362846216000404	0.947046877906743
GO:0002039	p53 binding	16/3891	69/18639	0.231884057971014	1.11079078810633	0.36298305320607	0.947046877906743
GO:0019789	SUMO transferase activity	7/3891	28/18639	0.25	1.19757131842714	0.364956078416639	0.947046877906743
GO:0045499	chemorepellent activity	7/3891	28/18639	0.25	1.19757131842714	0.364956078416639	0.947046877906743
GO:0046625	sphingolipid binding	7/3891	28/18639	0.25	1.19757131842714	0.364956078416639	0.947046877906743
GO:0046966	nuclear thyroid hormone receptor binding	7/3891	28/18639	0.25	1.19757131842714	0.364956078416639	0.947046877906743
GO:0051019	mitogen-activated protein kinase binding	7/3891	28/18639	0.25	1.19757131842714	0.364956078416639	0.947046877906743
GO:0004197	cysteine-type endopeptidase activity	20/3891	88/18639	0.227272727272727	1.08870119857013	0.374562311010418	0.969550939966394
GO:0031492	nucleosomal DNA binding	10/3891	42/18639	0.238095238095238	1.14054411278775	0.377540310633606	0.969550939966394
GO:0043175	RNA polymerase core enzyme binding	10/3891	42/18639	0.238095238095238	1.14054411278775	0.377540310633606	0.969550939966394
GO:0160215	deacylase activity	15/3891	65/18639	0.230769230769231	1.1054504477789	0.377735479436325	0.969550939966394
GO:0033293	monocarboxylic acid binding	18/3891	79/18639	0.227848101265823	1.09145740413613	0.380518300757954	0.969550939966394
GO:0005096	GTPase activator activity	59/3891	271/18639	0.217712177121771	1.04290343597345	0.380919193821541	0.969550939966394
GO:0019239	deaminase activity	8/3891	33/18639	0.242424242424242	1.1612812784748	0.381948715025218	0.969550939966394
GO:0051219	phosphoprotein binding	21/3891	93/18639	0.225806451612903	1.08167731986967	0.382011751800002	0.969550939966394
GO:0019888	protein phosphatase regulator activity	24/3891	107/18639	0.224299065420561	1.0744565099907	0.38269054131816	0.969550939966394
GO:0015556	C4-dicarboxylate transmembrane transporter activity	4/3891	15/18639	0.266666666666667	1.27740940632228	0.384824754805535	0.969550939966394
GO:0015929	hexosaminidase activity	4/3891	15/18639	0.266666666666667	1.27740940632228	0.384824754805535	0.969550939966394
GO:0004622	lysophospholipase activity	6/3891	24/18639	0.25	1.19757131842714	0.385213666962003	0.969550939966394
GO:0005540	hyaluronic acid binding	6/3891	24/18639	0.25	1.19757131842714	0.385213666962003	0.969550939966394
GO:0030215	semaphorin receptor binding	6/3891	24/18639	0.25	1.19757131842714	0.385213666962003	0.969550939966394
GO:0035035	histone acetyltransferase binding	6/3891	24/18639	0.25	1.19757131842714	0.385213666962003	0.969550939966394
GO:0140033	acetylation-dependent protein binding	6/3891	24/18639	0.25	1.19757131842714	0.385213666962003	0.969550939966394
GO:0004860	protein kinase inhibitor activity	19/3891	84/18639	0.226190476190476	1.08351690714836	0.388403798526533	0.975746128005682
GO:0001784	phosphotyrosine residue binding	11/3891	47/18639	0.234042553191489	1.12113059597434	0.389816431047055	0.977461050883907
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	9/3891	38/18639	0.236842105263158	1.13454124903624	0.396207640983798	0.991412221363942
GO:0019842	vitamin binding	33/3891	150/18639	0.22	1.05386276021588	0.398432458395616	0.991412221363942
GO:0030159	signaling receptor complex adaptor activity	12/3891	52/18639	0.230769230769231	1.1054504477789	0.400701658205871	0.991412221363942
GO:0061659	ubiquitin-like protein ligase activity	80/3891	372/18639	0.21505376344086	1.03016887606636	0.401776774196828	0.991412221363942
GO:0005496	steroid binding	24/3891	108/18639	0.222222222222222	1.0645078386019	0.402027084437884	0.991412221363942
GO:0099604	ligand-gated calcium channel activity	7/3891	29/18639	0.241379310344828	1.15627575572276	0.402683519322007	0.991412221363942
GO:0099106	ion channel regulator activity	35/3891	160/18639	0.21875	1.04787490362375	0.408113061418889	0.991412221363942
GO:0008200	ion channel inhibitor activity	10/3891	43/18639	0.232558139534884	1.11401983109501	0.40846693390211	0.991412221363942
GO:0016408	C-acyltransferase activity	5/3891	20/18639	0.25	1.19757131842714	0.408708289982053	0.991412221363942
GO:0030742	GTP-dependent protein binding	5/3891	20/18639	0.25	1.19757131842714	0.408708289982053	0.991412221363942
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	3/3891	11/18639	0.272727272727273	1.30644143828415	0.411669301776215	0.991412221363942
GO:0003953	NAD+ nucleosidase activity	3/3891	11/18639	0.272727272727273	1.30644143828415	0.411669301776215	0.991412221363942
GO:0004523	RNA-DNA hybrid ribonuclease activity	3/3891	11/18639	0.272727272727273	1.30644143828415	0.411669301776215	0.991412221363942
GO:0008046	axon guidance receptor activity	3/3891	11/18639	0.272727272727273	1.30644143828415	0.411669301776215	0.991412221363942
GO:0008432	JUN kinase binding	3/3891	11/18639	0.272727272727273	1.30644143828415	0.411669301776215	0.991412221363942
GO:0015205	nucleobase transmembrane transporter activity	3/3891	11/18639	0.272727272727273	1.30644143828415	0.411669301776215	0.991412221363942
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	3/3891	11/18639	0.272727272727273	1.30644143828415	0.411669301776215	0.991412221363942
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	3/3891	11/18639	0.272727272727273	1.30644143828415	0.411669301776215	0.991412221363942
GO:0019107	myristoyltransferase activity	3/3891	11/18639	0.272727272727273	1.30644143828415	0.411669301776215	0.991412221363942
GO:0019203	carbohydrate phosphatase activity	3/3891	11/18639	0.272727272727273	1.30644143828415	0.411669301776215	0.991412221363942
GO:0032050	clathrin heavy chain binding	3/3891	11/18639	0.272727272727273	1.30644143828415	0.411669301776215	0.991412221363942
GO:0032794	GTPase activating protein binding	3/3891	11/18639	0.272727272727273	1.30644143828415	0.411669301776215	0.991412221363942
GO:0008175	tRNA methyltransferase activity	8/3891	34/18639	0.235294117647059	1.12712594675496	0.416958923658771	0.999249162297
GO:0052866	phosphatidylinositol phosphate phosphatase activity	8/3891	34/18639	0.235294117647059	1.12712594675496	0.416958923658771	0.999249162297
GO:0019210	kinase inhibitor activity	20/3891	90/18639	0.222222222222222	1.0645078386019	0.417162271638553	0.999249162297
GO:0032266	phosphatidylinositol-3-phosphate binding	11/3891	48/18639	0.229166666666667	1.09777370855821	0.41920741587068	1
GO:0001618	virus receptor activity	18/3891	81/18639	0.222222222222222	1.0645078386019	0.425638265976483	1
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	6/3891	25/18639	0.24	1.14966846569005	0.426370496233227	1
GO:0003714	transcription corepressor activity	44/3891	204/18639	0.215686274509804	1.03319878452538	0.430823102344929	1
GO:0004707	MAP kinase activity	4/3891	16/18639	0.25	1.19757131842714	0.436881259224487	1
GO:0004708	MAP kinase kinase activity	4/3891	16/18639	0.25	1.19757131842714	0.436881259224487	1
GO:0005024	transforming growth factor beta receptor activity	4/3891	16/18639	0.25	1.19757131842714	0.436881259224487	1
GO:0005324	long-chain fatty acid transmembrane transporter activity	4/3891	16/18639	0.25	1.19757131842714	0.436881259224487	1
GO:0034450	ubiquitin-ubiquitin ligase activity	4/3891	16/18639	0.25	1.19757131842714	0.436881259224487	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	4/3891	16/18639	0.25	1.19757131842714	0.436881259224487	1
GO:0070411	I-SMAD binding	4/3891	16/18639	0.25	1.19757131842714	0.436881259224487	1
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	4/3891	16/18639	0.25	1.19757131842714	0.436881259224487	1
GO:0016248	channel inhibitor activity	10/3891	44/18639	0.227272727272727	1.08870119857013	0.439417084851759	1
GO:0016769	transferase activity, transferring nitrogenous groups	7/3891	30/18639	0.233333333333333	1.117733230532	0.4403249335883	1
GO:0070566	adenylyltransferase activity	7/3891	30/18639	0.233333333333333	1.117733230532	0.4403249335883	1
GO:0016407	acetyltransferase activity	21/3891	96/18639	0.21875	1.04787490362375	0.444509077202685	1
GO:0001221	transcription coregulator binding	25/3891	115/18639	0.217391304347826	1.04136636384969	0.446201882460532	1
GO:0140272	exogenous protein binding	18/3891	82/18639	0.219512195121951	1.05152603569212	0.448286508835831	1
GO:0035254	glutamate receptor binding	11/3891	49/18639	0.224489795918367	1.07537016348559	0.448584671604972	1
GO:0000175	3'-5'-RNA exonuclease activity	8/3891	35/18639	0.228571428571429	1.09492234827624	0.451844587431168	1
GO:0140566	histone reader activity	8/3891	35/18639	0.228571428571429	1.09492234827624	0.451844587431168	1
GO:0030295	protein kinase activator activity	30/3891	139/18639	0.215827338129496	1.03387451950544	0.451848354621318	1
GO:0140223	general transcription initiation factor activity	15/3891	68/18639	0.220588235294118	1.05668057508277	0.452351916551187	1
GO:0061630	ubiquitin protein ligase activity	75/3891	353/18639	0.212464589235127	1.01776599299757	0.452565915045566	1
GO:0001846	opsonin binding	5/3891	21/18639	0.238095238095238	1.14054411278775	0.45407095285141	1
GO:0005123	death receptor binding	5/3891	21/18639	0.238095238095238	1.14054411278775	0.45407095285141	1
GO:0009975	cyclase activity	5/3891	21/18639	0.238095238095238	1.14054411278775	0.45407095285141	1
GO:0010314	phosphatidylinositol-5-phosphate binding	5/3891	21/18639	0.238095238095238	1.14054411278775	0.45407095285141	1
GO:0051010	microtubule plus-end binding	5/3891	21/18639	0.238095238095238	1.14054411278775	0.45407095285141	1
GO:0070182	DNA polymerase binding	5/3891	21/18639	0.238095238095238	1.14054411278775	0.45407095285141	1
GO:0140463	chromatin-protein adaptor activity	12/3891	54/18639	0.222222222222222	1.0645078386019	0.456776228797392	1
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	9/3891	40/18639	0.225	1.07781418658443	0.461654926871892	1
GO:0004112	cyclic-nucleotide phosphodiesterase activity	6/3891	26/18639	0.230769230769231	1.1054504477789	0.467079031363764	1
GO:0004529	DNA exonuclease activity	6/3891	26/18639	0.230769230769231	1.1054504477789	0.467079031363764	1
GO:0005160	transforming growth factor beta receptor binding	6/3891	26/18639	0.230769230769231	1.1054504477789	0.467079031363764	1
GO:0008143	poly(A) binding	6/3891	26/18639	0.230769230769231	1.1054504477789	0.467079031363764	1
GO:0008157	protein phosphatase 1 binding	6/3891	26/18639	0.230769230769231	1.1054504477789	0.467079031363764	1
GO:0015216	purine nucleotide transmembrane transporter activity	6/3891	26/18639	0.230769230769231	1.1054504477789	0.467079031363764	1
GO:0141110	transporter inhibitor activity	10/3891	45/18639	0.222222222222222	1.0645078386019	0.470205119926039	1
GO:0004032	aldose reductase (NADPH) activity	3/3891	12/18639	0.25	1.19757131842714	0.472513075366568	1
GO:0005025	transforming growth factor beta receptor activity, type I	3/3891	12/18639	0.25	1.19757131842714	0.472513075366568	1
GO:0005026	transforming growth factor beta receptor activity, type II	3/3891	12/18639	0.25	1.19757131842714	0.472513075366568	1
GO:0005247	voltage-gated chloride channel activity	3/3891	12/18639	0.25	1.19757131842714	0.472513075366568	1
GO:0016208	AMP binding	3/3891	12/18639	0.25	1.19757131842714	0.472513075366568	1
GO:0016361	activin receptor activity, type I	3/3891	12/18639	0.25	1.19757131842714	0.472513075366568	1
GO:0016362	activin receptor activity, type II	3/3891	12/18639	0.25	1.19757131842714	0.472513075366568	1
GO:0016801	hydrolase activity, acting on ether bonds	3/3891	12/18639	0.25	1.19757131842714	0.472513075366568	1
GO:0016803	ether hydrolase activity	3/3891	12/18639	0.25	1.19757131842714	0.472513075366568	1
GO:0017002	activin receptor activity	3/3891	12/18639	0.25	1.19757131842714	0.472513075366568	1
GO:0031543	peptidyl-proline dioxygenase activity	3/3891	12/18639	0.25	1.19757131842714	0.472513075366568	1
GO:0035251	UDP-glucosyltransferase activity	3/3891	12/18639	0.25	1.19757131842714	0.472513075366568	1
GO:0035259	nuclear glucocorticoid receptor binding	3/3891	12/18639	0.25	1.19757131842714	0.472513075366568	1
GO:0036009	protein-glutamine N-methyltransferase activity	3/3891	12/18639	0.25	1.19757131842714	0.472513075366568	1
GO:0043047	single-stranded telomeric DNA binding	3/3891	12/18639	0.25	1.19757131842714	0.472513075366568	1
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	3/3891	12/18639	0.25	1.19757131842714	0.472513075366568	1
GO:0070008	serine-type exopeptidase activity	3/3891	12/18639	0.25	1.19757131842714	0.472513075366568	1
GO:0070679	inositol 1,4,5 trisphosphate binding	3/3891	12/18639	0.25	1.19757131842714	0.472513075366568	1
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	3/3891	12/18639	0.25	1.19757131842714	0.472513075366568	1
GO:1990247	N6-methyladenosine-containing RNA reader activity	3/3891	12/18639	0.25	1.19757131842714	0.472513075366568	1
GO:1990817	poly(A) RNA polymerase activity	3/3891	12/18639	0.25	1.19757131842714	0.472513075366568	1
GO:0015605	organophosphate ester transmembrane transporter activity	11/3891	50/18639	0.22	1.05386276021588	0.477790933809246	1
GO:0031491	nucleosome binding	16/3891	74/18639	0.216216216216216	1.03573735647753	0.482952223209078	1
GO:0008374	O-acyltransferase activity	12/3891	55/18639	0.218181818181818	1.04515315062732	0.484616631605225	1
GO:0042626	ATPase-coupled transmembrane transporter activity	21/3891	98/18639	0.214285714285714	1.02648970150898	0.486224129448491	1
GO:0004033	aldo-keto reductase (NADPH) activity	8/3891	36/18639	0.222222222222222	1.0645078386019	0.486350060474161	1
GO:0004029	aldehyde dehydrogenase (NAD+) activity	4/3891	17/18639	0.235294117647059	1.12712594675496	0.487578182325708	1
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	4/3891	17/18639	0.235294117647059	1.12712594675496	0.487578182325708	1
GO:0008429	phosphatidylethanolamine binding	4/3891	17/18639	0.235294117647059	1.12712594675496	0.487578182325708	1
GO:0017110	nucleoside diphosphate phosphatase activity	4/3891	17/18639	0.235294117647059	1.12712594675496	0.487578182325708	1
GO:0038191	neuropilin binding	4/3891	17/18639	0.235294117647059	1.12712594675496	0.487578182325708	1
GO:0015631	tubulin binding	81/3891	385/18639	0.21038961038961	1.00782625239063	0.488770211176717	1
GO:0004722	protein serine/threonine phosphatase activity	22/3891	103/18639	0.213592233009709	1.02316772836493	0.490806028537612	1
GO:0001727	lipid kinase activity	9/3891	41/18639	0.219512195121951	1.05152603569212	0.49394876250245	1
GO:0120013	lipid transfer activity	14/3891	65/18639	0.215384615384615	1.0317537512603	0.496535712240397	1
GO:0030021	extracellular matrix structural constituent conferring compression resistance	5/3891	22/18639	0.227272727272727	1.08870119857013	0.498411147783636	1
GO:0033691	sialic acid binding	5/3891	22/18639	0.227272727272727	1.08870119857013	0.498411147783636	1
GO:0030276	clathrin binding	10/3891	46/18639	0.217391304347826	1.04136636384969	0.500657440570325	1
GO:0001671	ATPase activator activity	6/3891	27/18639	0.222222222222222	1.0645078386019	0.506960112790383	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	6/3891	27/18639	0.222222222222222	1.0645078386019	0.506960112790383	1
GO:0048306	calcium-dependent protein binding	17/3891	80/18639	0.2125	1.01793562066307	0.511361988619243	1
GO:0031369	translation initiation factor binding	7/3891	32/18639	0.21875	1.04787490362375	0.514086767702345	1
GO:0035198	miRNA binding	9/3891	42/18639	0.214285714285714	1.02648970150898	0.525696522103043	1
GO:0042056	chemoattractant activity	9/3891	42/18639	0.214285714285714	1.02648970150898	0.525696522103043	1
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	3/3891	13/18639	0.230769230769231	1.1054504477789	0.530285752380464	1
GO:0008035	high-density lipoprotein particle binding	3/3891	13/18639	0.230769230769231	1.1054504477789	0.530285752380464	1
GO:0008253	5'-nucleotidase activity	3/3891	13/18639	0.230769230769231	1.1054504477789	0.530285752380464	1
GO:0032396	inhibitory MHC class I receptor activity	3/3891	13/18639	0.230769230769231	1.1054504477789	0.530285752380464	1
GO:0035673	oligopeptide transmembrane transporter activity	3/3891	13/18639	0.230769230769231	1.1054504477789	0.530285752380464	1
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	3/3891	13/18639	0.230769230769231	1.1054504477789	0.530285752380464	1
GO:0046974	histone H3K9 methyltransferase activity	3/3891	13/18639	0.230769230769231	1.1054504477789	0.530285752380464	1
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	3/3891	13/18639	0.230769230769231	1.1054504477789	0.530285752380464	1
GO:0070123	transforming growth factor beta receptor activity, type III	3/3891	13/18639	0.230769230769231	1.1054504477789	0.530285752380464	1
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	3/3891	13/18639	0.230769230769231	1.1054504477789	0.530285752380464	1
GO:0000400	four-way junction DNA binding	4/3891	18/18639	0.222222222222222	1.0645078386019	0.536289099337232	1
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	4/3891	18/18639	0.222222222222222	1.0645078386019	0.536289099337232	1
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	4/3891	18/18639	0.222222222222222	1.0645078386019	0.536289099337232	1
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	4/3891	18/18639	0.222222222222222	1.0645078386019	0.536289099337232	1
GO:0070628	proteasome binding	4/3891	18/18639	0.222222222222222	1.0645078386019	0.536289099337232	1
GO:0015932	nucleobase-containing compound transmembrane transporter activity	12/3891	57/18639	0.210526315789474	1.00848111025443	0.539268106178484	1
GO:0000295	adenine nucleotide transmembrane transporter activity	5/3891	23/18639	0.217391304347826	1.04136636384969	0.54129268095232	1
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	5/3891	23/18639	0.217391304347826	1.04136636384969	0.54129268095232	1
GO:0005158	insulin receptor binding	5/3891	23/18639	0.217391304347826	1.04136636384969	0.54129268095232	1
GO:0043274	phospholipase binding	5/3891	23/18639	0.217391304347826	1.04136636384969	0.54129268095232	1
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	5/3891	23/18639	0.217391304347826	1.04136636384969	0.54129268095232	1
GO:0016866	intramolecular transferase activity	6/3891	28/18639	0.214285714285714	1.02648970150898	0.545688485801404	1
GO:0051119	sugar transmembrane transporter activity	6/3891	28/18639	0.214285714285714	1.02648970150898	0.545688485801404	1
GO:0097718	disordered domain specific binding	6/3891	28/18639	0.214285714285714	1.02648970150898	0.545688485801404	1
GO:0019956	chemokine binding	7/3891	33/18639	0.212121212121212	1.01612111866545	0.549662397269265	1
GO:0140416	transcription regulator inhibitor activity	7/3891	33/18639	0.212121212121212	1.01612111866545	0.549662397269265	1
GO:0042162	telomeric DNA binding	8/3891	38/18639	0.210526315789474	1.00848111025443	0.553319894047945	1
GO:0052689	carboxylic ester hydrolase activity	19/3891	92/18639	0.206521739130435	0.989298045657202	0.562405771581563	1
GO:0016251	RNA polymerase II general transcription initiation factor activity	11/3891	53/18639	0.207547169811321	0.994210151147059	0.562965600245913	1
GO:0008408	3'-5' exonuclease activity	12/3891	58/18639	0.206896551724138	0.991093504905219	0.565853130714802	1
GO:0016779	nucleotidyltransferase activity	28/3891	136/18639	0.205882352941176	0.986235203410585	0.567025341154291	1
GO:0030165	PDZ domain binding	17/3891	83/18639	0.204819277108434	0.981142766904162	0.578655839071469	1
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	5/3891	24/18639	0.208333333333333	0.997976098689283	0.582366105686615	1
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	5/3891	24/18639	0.208333333333333	0.997976098689283	0.582366105686615	1
GO:0015295	solute:proton symporter activity	5/3891	24/18639	0.208333333333333	0.997976098689283	0.582366105686615	1
GO:0050699	WW domain binding	5/3891	24/18639	0.208333333333333	0.997976098689283	0.582366105686615	1
GO:0140612	DNA damage sensor activity	5/3891	24/18639	0.208333333333333	0.997976098689283	0.582366105686615	1
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	4/3891	19/18639	0.210526315789474	1.00848111025443	0.58254053489372	1
GO:0008574	plus-end-directed microtubule motor activity	4/3891	19/18639	0.210526315789474	1.00848111025443	0.58254053489372	1
GO:0015245	fatty acid transmembrane transporter activity	4/3891	19/18639	0.210526315789474	1.00848111025443	0.58254053489372	1
GO:0022840	leak channel activity	4/3891	19/18639	0.210526315789474	1.00848111025443	0.58254053489372	1
GO:0022842	narrow pore channel activity	4/3891	19/18639	0.210526315789474	1.00848111025443	0.58254053489372	1
GO:0043395	heparan sulfate proteoglycan binding	4/3891	19/18639	0.210526315789474	1.00848111025443	0.58254053489372	1
GO:0046527	glucosyltransferase activity	4/3891	19/18639	0.210526315789474	1.00848111025443	0.58254053489372	1
GO:0140036	ubiquitin-modified protein reader activity	4/3891	19/18639	0.210526315789474	1.00848111025443	0.58254053489372	1
GO:0004181	metallocarboxypeptidase activity	6/3891	29/18639	0.206896551724138	0.991093504905219	0.582994129230812	1
GO:0004629	phospholipase C activity	6/3891	29/18639	0.206896551724138	0.991093504905219	0.582994129230812	1
GO:0016417	S-acyltransferase activity	6/3891	29/18639	0.206896551724138	0.991093504905219	0.582994129230812	1
GO:0090482	vitamin transmembrane transporter activity	7/3891	34/18639	0.205882352941176	0.986235203410585	0.584067001538652	1
GO:0004065	arylsulfatase activity	3/3891	14/18639	0.214285714285714	1.02648970150898	0.584310421122109	1
GO:0005161	platelet-derived growth factor receptor binding	3/3891	14/18639	0.214285714285714	1.02648970150898	0.584310421122109	1
GO:0005344	oxygen carrier activity	3/3891	14/18639	0.214285714285714	1.02648970150898	0.584310421122109	1
GO:0008559	ABC-type xenobiotic transporter activity	3/3891	14/18639	0.214285714285714	1.02648970150898	0.584310421122109	1
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	3/3891	14/18639	0.214285714285714	1.02648970150898	0.584310421122109	1
GO:0034236	protein kinase A catalytic subunit binding	3/3891	14/18639	0.214285714285714	1.02648970150898	0.584310421122109	1
GO:0071933	Arp2/3 complex binding	3/3891	14/18639	0.214285714285714	1.02648970150898	0.584310421122109	1
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	3/3891	14/18639	0.214285714285714	1.02648970150898	0.584310421122109	1
GO:0098821	BMP receptor activity	3/3891	14/18639	0.214285714285714	1.02648970150898	0.584310421122109	1
GO:0098847	sequence-specific single stranded DNA binding	3/3891	14/18639	0.214285714285714	1.02648970150898	0.584310421122109	1
GO:1990825	sequence-specific mRNA binding	3/3891	14/18639	0.214285714285714	1.02648970150898	0.584310421122109	1
GO:0001046	core promoter sequence-specific DNA binding	9/3891	44/18639	0.204545454545455	0.979831078713114	0.5868935176715	1
GO:0003779	actin binding	91/3891	443/18639	0.205417607223476	0.984008938843067	0.588506429313995	1
GO:0036002	pre-mRNA binding	12/3891	59/18639	0.203389830508475	0.974295309906825	0.591811328441959	1
GO:0016279	protein-lysine N-methyltransferase activity	14/3891	69/18639	0.202898550724638	0.971941939593041	0.595212569712833	1
GO:0008201	heparin binding	35/3891	172/18639	0.203488372093023	0.974767352208137	0.597948396787628	1
GO:0019209	kinase activator activity	30/3891	148/18639	0.202702702702703	0.971003771697681	0.604599275149762	1
GO:0005126	cytokine receptor binding	56/3891	275/18639	0.203636363636364	0.975476273918834	0.607222314015243	1
GO:0046915	transition metal ion transmembrane transporter activity	9/3891	45/18639	0.2	0.958057054741712	0.616065617107865	1
GO:0015144	carbohydrate transmembrane transporter activity	8/3891	40/18639	0.2	0.958057054741712	0.616337659010121	1
GO:0030331	nuclear estrogen receptor binding	8/3891	40/18639	0.2	0.958057054741712	0.616337659010121	1
GO:0050997	quaternary ammonium group binding	8/3891	40/18639	0.2	0.958057054741712	0.616337659010121	1
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	12/3891	60/18639	0.2	0.958057054741712	0.617056973874356	1
GO:0070851	growth factor receptor binding	28/3891	139/18639	0.201438848920863	0.964949551538415	0.61768441002765	1
GO:0016278	lysine N-methyltransferase activity	14/3891	70/18639	0.2	0.958057054741712	0.618560745413353	1
GO:0016782	transferase activity, transferring sulphur-containing groups	14/3891	70/18639	0.2	0.958057054741712	0.618560745413353	1
GO:0015215	nucleotide transmembrane transporter activity	6/3891	30/18639	0.2	0.958057054741712	0.61866142814144	1
GO:0031210	phosphatidylcholine binding	6/3891	30/18639	0.2	0.958057054741712	0.61866142814144	1
GO:0051721	protein phosphatase 2A binding	6/3891	30/18639	0.2	0.958057054741712	0.61866142814144	1
GO:0008017	microtubule binding	56/3891	276/18639	0.202898550724638	0.971941939593041	0.619055676604831	1
GO:0001848	complement binding	5/3891	25/18639	0.2	0.958057054741712	0.621365008049962	1
GO:0008483	transaminase activity	5/3891	25/18639	0.2	0.958057054741712	0.621365008049962	1
GO:0019706	protein-cysteine S-palmitoyltransferase activity	5/3891	25/18639	0.2	0.958057054741712	0.621365008049962	1
GO:0019707	protein-cysteine S-acyltransferase activity	5/3891	25/18639	0.2	0.958057054741712	0.621365008049962	1
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	5/3891	25/18639	0.2	0.958057054741712	0.621365008049962	1
GO:0010851	cyclase regulator activity	4/3891	20/18639	0.2	0.958057054741712	0.625998596121637	1
GO:0031418	L-ascorbic acid binding	4/3891	20/18639	0.2	0.958057054741712	0.625998596121637	1
GO:0052745	inositol phosphate phosphatase activity	4/3891	20/18639	0.2	0.958057054741712	0.625998596121637	1
GO:0140664	ATP-dependent DNA damage sensor activity	4/3891	20/18639	0.2	0.958057054741712	0.625998596121637	1
GO:0035401	histone H3Y41 kinase activity	23/3891	115/18639	0.2	0.958057054741712	0.628135549003483	1
GO:0140801	histone H2AXY142 kinase activity	23/3891	115/18639	0.2	0.958057054741712	0.628135549003483	1
GO:0008237	metallopeptidase activity	37/3891	184/18639	0.201086956521739	0.96326388656096	0.630375303120268	1
GO:0004953	icosanoid receptor activity	3/3891	15/18639	0.2	0.958057054741712	0.634181837701252	1
GO:0005402	carbohydrate:monoatomic cation symporter activity	3/3891	15/18639	0.2	0.958057054741712	0.634181837701252	1
GO:0008252	nucleotidase activity	3/3891	15/18639	0.2	0.958057054741712	0.634181837701252	1
GO:0017081	chloride channel regulator activity	3/3891	15/18639	0.2	0.958057054741712	0.634181837701252	1
GO:0031005	filamin binding	3/3891	15/18639	0.2	0.958057054741712	0.634181837701252	1
GO:0033130	acetylcholine receptor binding	3/3891	15/18639	0.2	0.958057054741712	0.634181837701252	1
GO:0042809	nuclear vitamin D receptor binding	3/3891	15/18639	0.2	0.958057054741712	0.634181837701252	1
GO:0045504	dynein heavy chain binding	3/3891	15/18639	0.2	0.958057054741712	0.634181837701252	1
GO:0061578	K63-linked deubiquitinase activity	3/3891	15/18639	0.2	0.958057054741712	0.634181837701252	1
GO:0098631	cell adhesion mediator activity	15/3891	76/18639	0.197368421052632	0.945451040863531	0.6413849281638	1
GO:0030170	pyridoxal phosphate binding	11/3891	56/18639	0.196428571428571	0.940948893049895	0.642017855649262	1
GO:0005021	vascular endothelial growth factor receptor activity	10/3891	51/18639	0.196078431372549	0.939271622295796	0.642857414925716	1
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	9/3891	46/18639	0.195652173913043	0.937229727464718	0.644137876265645	1
GO:0030291	protein serine/threonine kinase inhibitor activity	9/3891	46/18639	0.195652173913043	0.937229727464718	0.644137876265645	1
GO:0005484	SNAP receptor activity	7/3891	36/18639	0.194444444444444	0.931444358776664	0.648688391691024	1
GO:0016409	palmitoyltransferase activity	7/3891	36/18639	0.194444444444444	0.931444358776664	0.648688391691024	1
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	2/3891	10/18639	0.2	0.958057054741712	0.650117613564004	1
GO:0004445	inositol-polyphosphate 5-phosphatase activity	2/3891	10/18639	0.2	0.958057054741712	0.650117613564004	1
GO:0004935	adrenergic receptor activity	2/3891	10/18639	0.2	0.958057054741712	0.650117613564004	1
GO:0004955	prostaglandin receptor activity	2/3891	10/18639	0.2	0.958057054741712	0.650117613564004	1
GO:0005131	growth hormone receptor binding	2/3891	10/18639	0.2	0.958057054741712	0.650117613564004	1
GO:0005381	iron ion transmembrane transporter activity	2/3891	10/18639	0.2	0.958057054741712	0.650117613564004	1
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	2/3891	10/18639	0.2	0.958057054741712	0.650117613564004	1
GO:0016868	intramolecular phosphotransferase activity	2/3891	10/18639	0.2	0.958057054741712	0.650117613564004	1
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	2/3891	10/18639	0.2	0.958057054741712	0.650117613564004	1
GO:0019911	structural constituent of myelin sheath	2/3891	10/18639	0.2	0.958057054741712	0.650117613564004	1
GO:0031720	haptoglobin binding	2/3891	10/18639	0.2	0.958057054741712	0.650117613564004	1
GO:0031957	very long-chain fatty acid-CoA ligase activity	2/3891	10/18639	0.2	0.958057054741712	0.650117613564004	1
GO:0032395	MHC class II receptor activity	2/3891	10/18639	0.2	0.958057054741712	0.650117613564004	1
GO:0035374	chondroitin sulfate binding	2/3891	10/18639	0.2	0.958057054741712	0.650117613564004	1
GO:0043208	glycosphingolipid binding	2/3891	10/18639	0.2	0.958057054741712	0.650117613564004	1
GO:0045322	unmethylated CpG binding	2/3891	10/18639	0.2	0.958057054741712	0.650117613564004	1
GO:0051864	histone H3K36 demethylase activity	2/3891	10/18639	0.2	0.958057054741712	0.650117613564004	1
GO:0070097	delta-catenin binding	2/3891	10/18639	0.2	0.958057054741712	0.650117613564004	1
GO:0098505	G-rich strand telomeric DNA binding	2/3891	10/18639	0.2	0.958057054741712	0.650117613564004	1
GO:0099122	RNA polymerase II C-terminal domain binding	2/3891	10/18639	0.2	0.958057054741712	0.650117613564004	1
GO:0016878	acid-thiol ligase activity	6/3891	31/18639	0.193548387096774	0.927151988459721	0.65252667458091	1
GO:0015145	monosaccharide transmembrane transporter activity	5/3891	26/18639	0.192307692307692	0.921208706482415	0.658099764403818	1
GO:0019865	immunoglobulin binding	5/3891	26/18639	0.192307692307692	0.921208706482415	0.658099764403818	1
GO:0034237	protein kinase A regulatory subunit binding	5/3891	26/18639	0.192307692307692	0.921208706482415	0.658099764403818	1
GO:0120014	phospholipid transfer activity	5/3891	26/18639	0.192307692307692	0.921208706482415	0.658099764403818	1
GO:0050840	extracellular matrix binding	13/3891	67/18639	0.194029850746269	0.92945833668972	0.664026198003115	1
GO:0030246	carbohydrate binding	56/3891	280/18639	0.2	0.958057054741712	0.664888958721771	1
GO:0020037	heme binding	28/3891	142/18639	0.197183098591549	0.944563293407321	0.665651183655425	1
GO:0061134	peptidase regulator activity	45/3891	226/18639	0.199115044247788	0.953817864234005	0.66579146912258	1
GO:0008373	sialyltransferase activity	4/3891	21/18639	0.19047619047619	0.912435290230202	0.666452159244043	1
GO:0009931	calcium-dependent protein serine/threonine kinase activity	4/3891	21/18639	0.19047619047619	0.912435290230202	0.666452159244043	1
GO:0070279	vitamin B6 binding	11/3891	57/18639	0.192982456140351	0.924441017733231	0.666588447914013	1
GO:0061749	forked DNA-dependent helicase activity	9/3891	47/18639	0.191489361702128	0.917288669433554	0.671024998761697	1
GO:0140938	histone H3 methyltransferase activity	9/3891	47/18639	0.191489361702128	0.917288669433554	0.671024998761697	1
GO:1990518	single-stranded 3'-5' DNA helicase activity	9/3891	47/18639	0.191489361702128	0.917288669433554	0.671024998761697	1
GO:0022829	wide pore channel activity	7/3891	37/18639	0.189189189189189	0.906270186917835	0.678658836028437	1
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	3/3891	16/18639	0.1875	0.898178488820355	0.679712740426659	1
GO:0005149	interleukin-1 receptor binding	3/3891	16/18639	0.1875	0.898178488820355	0.679712740426659	1
GO:0008142	oxysterol binding	3/3891	16/18639	0.1875	0.898178488820355	0.679712740426659	1
GO:0008296	3'-5'-DNA exonuclease activity	3/3891	16/18639	0.1875	0.898178488820355	0.679712740426659	1
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	3/3891	16/18639	0.1875	0.898178488820355	0.679712740426659	1
GO:0022841	potassium ion leak channel activity	3/3891	16/18639	0.1875	0.898178488820355	0.679712740426659	1
GO:0030275	LRR domain binding	3/3891	16/18639	0.1875	0.898178488820355	0.679712740426659	1
GO:0005543	phospholipid binding	100/3891	497/18639	0.201207243460765	0.963840095313593	0.679957138955031	1
GO:0008378	galactosyltransferase activity	6/3891	32/18639	0.1875	0.898178488820355	0.684474345399041	1
GO:0042910	xenobiotic transmembrane transporter activity	6/3891	32/18639	0.1875	0.898178488820355	0.684474345399041	1
GO:1990841	promoter-specific chromatin binding	13/3891	68/18639	0.191176470588235	0.915789831738401	0.685951987440802	1
GO:0017116	single-stranded DNA helicase activity	11/3891	58/18639	0.189655172413793	0.908502379496451	0.690164798747871	1
GO:0008266	poly(U) RNA binding	5/3891	27/18639	0.185185185185185	0.887089865501585	0.692449685225052	1
GO:0034212	protein N-acetyltransferase activity	10/3891	53/18639	0.188679245283019	0.90382741013369	0.693056695415368	1
GO:0009378	four-way junction helicase activity	9/3891	48/18639	0.1875	0.898178488820355	0.696661817851372	1
GO:0016879	ligase activity, forming carbon-nitrogen bonds	9/3891	48/18639	0.1875	0.898178488820355	0.696661817851372	1
GO:0036121	double-stranded DNA helicase activity	9/3891	48/18639	0.1875	0.898178488820355	0.696661817851372	1
GO:0043138	3'-5' DNA helicase activity	9/3891	48/18639	0.1875	0.898178488820355	0.696661817851372	1
GO:0140693	molecular condensate scaffold activity	9/3891	48/18639	0.1875	0.898178488820355	0.696661817851372	1
GO:0004712	protein serine/threonine/tyrosine kinase activity	8/3891	43/18639	0.186046511627907	0.891215864876011	0.701193536428621	1
GO:0008375	acetylglucosaminyltransferase activity	8/3891	43/18639	0.186046511627907	0.891215864876011	0.701193536428621	1
GO:0048156	tau protein binding	8/3891	43/18639	0.186046511627907	0.891215864876011	0.701193536428621	1
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	45/3891	229/18639	0.196506550218341	0.941322433698188	0.701781335910486	1
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	2/3891	11/18639	0.181818181818182	0.870960958856101	0.703106127294624	1
GO:0001851	complement component C3b binding	2/3891	11/18639	0.181818181818182	0.870960958856101	0.703106127294624	1
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	2/3891	11/18639	0.181818181818182	0.870960958856101	0.703106127294624	1
GO:0004954	prostanoid receptor activity	2/3891	11/18639	0.181818181818182	0.870960958856101	0.703106127294624	1
GO:0005114	type II transforming growth factor beta receptor binding	2/3891	11/18639	0.181818181818182	0.870960958856101	0.703106127294624	1
GO:0008199	ferric iron binding	2/3891	11/18639	0.181818181818182	0.870960958856101	0.703106127294624	1
GO:0008503	benzodiazepine receptor activity	2/3891	11/18639	0.181818181818182	0.870960958856101	0.703106127294624	1
GO:0008526	phosphatidylinositol transfer activity	2/3891	11/18639	0.181818181818182	0.870960958856101	0.703106127294624	1
GO:0016176	superoxide-generating NADPH oxidase activator activity	2/3891	11/18639	0.181818181818182	0.870960958856101	0.703106127294624	1
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	2/3891	11/18639	0.181818181818182	0.870960958856101	0.703106127294624	1
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	2/3891	11/18639	0.181818181818182	0.870960958856101	0.703106127294624	1
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	2/3891	11/18639	0.181818181818182	0.870960958856101	0.703106127294624	1
GO:0042608	T cell receptor binding	2/3891	11/18639	0.181818181818182	0.870960958856101	0.703106127294624	1
GO:0047676	arachidonate-CoA ligase activity	2/3891	11/18639	0.181818181818182	0.870960958856101	0.703106127294624	1
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	2/3891	11/18639	0.181818181818182	0.870960958856101	0.703106127294624	1
GO:0048185	activin binding	2/3891	11/18639	0.181818181818182	0.870960958856101	0.703106127294624	1
GO:0050998	nitric-oxide synthase binding	2/3891	11/18639	0.181818181818182	0.870960958856101	0.703106127294624	1
GO:0070697	activin receptor binding	2/3891	11/18639	0.181818181818182	0.870960958856101	0.703106127294624	1
GO:0140537	transcription regulator activator activity	2/3891	11/18639	0.181818181818182	0.870960958856101	0.703106127294624	1
GO:0016881	acid-amino acid ligase activity	4/3891	22/18639	0.181818181818182	0.870960958856101	0.703794606235245	1
GO:0140784	metal ion sensor activity	4/3891	22/18639	0.181818181818182	0.870960958856101	0.703794606235245	1
GO:0005501	retinoid binding	7/3891	38/18639	0.184210526315789	0.882420971472629	0.706961177765968	1
GO:0019840	isoprenoid binding	7/3891	38/18639	0.184210526315789	0.882420971472629	0.706961177765968	1
GO:0008080	N-acetyltransferase activity	13/3891	69/18639	0.188405797101449	0.902517515336395	0.707016495127651	1
GO:0004713	protein tyrosine kinase activity	27/3891	140/18639	0.192857142857143	0.923840731358079	0.71058278368562	1
GO:0001786	phosphatidylserine binding	11/3891	59/18639	0.186440677966102	0.893104034081257	0.712704135692976	1
GO:0005092	GDP-dissociation inhibitor activity	3/3891	17/18639	0.176470588235294	0.845344460066216	0.720884431448292	1
GO:0008484	sulfuric ester hydrolase activity	3/3891	17/18639	0.176470588235294	0.845344460066216	0.720884431448292	1
GO:0031489	myosin V binding	3/3891	17/18639	0.176470588235294	0.845344460066216	0.720884431448292	1
GO:0032183	SUMO binding	3/3891	17/18639	0.176470588235294	0.845344460066216	0.720884431448292	1
GO:0046965	nuclear retinoid X receptor binding	3/3891	17/18639	0.176470588235294	0.845344460066216	0.720884431448292	1
GO:0036408	histone H3K14 acetyltransferase activity	5/3891	28/18639	0.178571428571429	0.855408084590814	0.724354293795411	1
GO:0051959	dynein light intermediate chain binding	5/3891	28/18639	0.178571428571429	0.855408084590814	0.724354293795411	1
GO:0016790	thiolester hydrolase activity	8/3891	44/18639	0.181818181818182	0.870960958856101	0.72659354059687	1
GO:0008013	beta-catenin binding	20/3891	106/18639	0.188679245283019	0.90382741013369	0.73089309135158	1
GO:0000217	DNA secondary structure binding	7/3891	39/18639	0.179487179487179	0.859794792716921	0.733552442024857	1
GO:0046906	tetrapyrrole binding	29/3891	152/18639	0.190789473684211	0.91393600616808	0.737622627660297	1
GO:0005283	amino acid:sodium symporter activity	4/3891	23/18639	0.173913043478261	0.833093091079749	0.738005537873755	1
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	4/3891	23/18639	0.173913043478261	0.833093091079749	0.738005537873755	1
GO:0004857	enzyme inhibitor activity	82/3891	416/18639	0.197115384615385	0.944238924144475	0.740603525660989	1
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	6/3891	34/18639	0.176470588235294	0.845344460066216	0.74236803207081	1
GO:0017022	myosin binding	14/3891	76/18639	0.184210526315789	0.882420971472629	0.743215322439147	1
GO:0005095	GTPase inhibitor activity	2/3891	12/18639	0.166666666666667	0.798380878951426	0.749224737680235	1
GO:0008179	adenylate cyclase binding	2/3891	12/18639	0.166666666666667	0.798380878951426	0.749224737680235	1
GO:0008504	monoamine transmembrane transporter activity	2/3891	12/18639	0.166666666666667	0.798380878951426	0.749224737680235	1
GO:0016840	carbon-nitrogen lyase activity	2/3891	12/18639	0.166666666666667	0.798380878951426	0.749224737680235	1
GO:0035014	phosphatidylinositol 3-kinase regulator activity	2/3891	12/18639	0.166666666666667	0.798380878951426	0.749224737680235	1
GO:0035197	siRNA binding	2/3891	12/18639	0.166666666666667	0.798380878951426	0.749224737680235	1
GO:0045295	gamma-catenin binding	2/3891	12/18639	0.166666666666667	0.798380878951426	0.749224737680235	1
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	2/3891	12/18639	0.166666666666667	0.798380878951426	0.749224737680235	1
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	2/3891	12/18639	0.166666666666667	0.798380878951426	0.749224737680235	1
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	2/3891	12/18639	0.166666666666667	0.798380878951426	0.749224737680235	1
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	2/3891	12/18639	0.166666666666667	0.798380878951426	0.749224737680235	1
GO:0042605	peptide antigen binding	8/3891	45/18639	0.177777777777778	0.851606270881521	0.750491469999898	1
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	5/3891	29/18639	0.172413793103448	0.825911254087683	0.753804328079702	1
GO:0010484	histone H3 acetyltransferase activity	5/3891	29/18639	0.172413793103448	0.825911254087683	0.753804328079702	1
GO:0035250	UDP-galactosyltransferase activity	5/3891	29/18639	0.172413793103448	0.825911254087683	0.753804328079702	1
GO:0097472	cyclin-dependent protein kinase activity	5/3891	29/18639	0.172413793103448	0.825911254087683	0.753804328079702	1
GO:0015026	coreceptor activity	11/3891	61/18639	0.180327868852459	0.863821934603183	0.754561167112538	1
GO:0019905	syntaxin binding	11/3891	61/18639	0.180327868852459	0.863821934603183	0.754561167112538	1
GO:0000900	mRNA regulatory element binding translation repressor activity	3/3891	18/18639	0.166666666666667	0.798380878951426	0.757803497870504	1
GO:0008525	phosphatidylcholine transporter activity	3/3891	18/18639	0.166666666666667	0.798380878951426	0.757803497870504	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	3/3891	18/18639	0.166666666666667	0.798380878951426	0.757803497870504	1
GO:0017075	syntaxin-1 binding	3/3891	18/18639	0.166666666666667	0.798380878951426	0.757803497870504	1
GO:0017128	phospholipid scramblase activity	3/3891	18/18639	0.166666666666667	0.798380878951426	0.757803497870504	1
GO:0032393	MHC class I receptor activity	3/3891	18/18639	0.166666666666667	0.798380878951426	0.757803497870504	1
GO:0098641	cadherin binding involved in cell-cell adhesion	3/3891	18/18639	0.166666666666667	0.798380878951426	0.757803497870504	1
GO:0061791	GTPase motor activity	7/3891	40/18639	0.175	0.838299922898998	0.758416183876468	1
GO:1990606	membrane scission GTPase motor activity	7/3891	40/18639	0.175	0.838299922898998	0.758416183876468	1
GO:0005048	signal sequence binding	9/3891	51/18639	0.176470588235294	0.845344460066216	0.765694268104924	1
GO:0010485	histone H4 acetyltransferase activity	6/3891	35/18639	0.171428571428571	0.821191761207181	0.768280879037421	1
GO:0016229	steroid dehydrogenase activity	6/3891	35/18639	0.171428571428571	0.821191761207181	0.768280879037421	1
GO:0015149	hexose transmembrane transporter activity	4/3891	24/18639	0.166666666666667	0.798380878951426	0.769133424311184	1
GO:0055056	D-glucose transmembrane transporter activity	4/3891	24/18639	0.166666666666667	0.798380878951426	0.769133424311184	1
GO:0070840	dynein complex binding	4/3891	24/18639	0.166666666666667	0.798380878951426	0.769133424311184	1
GO:0015179	L-amino acid transmembrane transporter activity	11/3891	62/18639	0.17741935483871	0.849889322754744	0.773851260817135	1
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	15/3891	83/18639	0.180722891566265	0.865714206091908	0.774580771266216	1
GO:0004620	phospholipase activity	20/3891	109/18639	0.18348623853211	0.878951426368543	0.77630101923614	1
GO:0008194	UDP-glycosyltransferase activity	27/3891	145/18639	0.186206896551724	0.891984154414697	0.777941333688319	1
GO:0019199	transmembrane receptor protein kinase activity	14/3891	78/18639	0.179487179487179	0.859794792716921	0.778158510482797	1
GO:0001965	G-protein alpha-subunit binding	5/3891	30/18639	0.166666666666667	0.798380878951426	0.780832908067355	1
GO:0001968	fibronectin binding	5/3891	30/18639	0.166666666666667	0.798380878951426	0.780832908067355	1
GO:0008187	poly-pyrimidine tract binding	5/3891	30/18639	0.166666666666667	0.798380878951426	0.780832908067355	1
GO:0043995	histone H4K5 acetyltransferase activity	5/3891	30/18639	0.166666666666667	0.798380878951426	0.780832908067355	1
GO:0043996	histone H4K8 acetyltransferase activity	5/3891	30/18639	0.166666666666667	0.798380878951426	0.780832908067355	1
GO:0043997	histone H4K12 acetyltransferase activity	5/3891	30/18639	0.166666666666667	0.798380878951426	0.780832908067355	1
GO:0015175	neutral L-amino acid transmembrane transporter activity	7/3891	41/18639	0.170731707317073	0.817853583316095	0.781559108154273	1
GO:0016410	N-acyltransferase activity	17/3891	94/18639	0.180851063829787	0.866328187798356	0.783887337522825	1
GO:0016757	glycosyltransferase activity	51/3891	267/18639	0.191011235955056	0.914998310708376	0.784977389703208	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	9/3891	52/18639	0.173076923076923	0.829087835834173	0.78603490906068	1
GO:0039706	co-receptor binding	2/3891	13/18639	0.153846153846154	0.736966965185932	0.789031825916557	1
GO:0045159	myosin II binding	2/3891	13/18639	0.153846153846154	0.736966965185932	0.789031825916557	1
GO:0046975	histone H3K36 methyltransferase activity	2/3891	13/18639	0.153846153846154	0.736966965185932	0.789031825916557	1
GO:0071714	icosanoid transmembrane transporter activity	2/3891	13/18639	0.153846153846154	0.736966965185932	0.789031825916557	1
GO:0071837	HMG box domain binding	2/3891	13/18639	0.153846153846154	0.736966965185932	0.789031825916557	1
GO:0089720	caspase binding	2/3891	13/18639	0.153846153846154	0.736966965185932	0.789031825916557	1
GO:0097157	pre-mRNA intronic binding	2/3891	13/18639	0.153846153846154	0.736966965185932	0.789031825916557	1
GO:0008381	mechanosensitive monoatomic ion channel activity	3/3891	19/18639	0.157894736842105	0.756360832690825	0.790665303428651	1
GO:0030506	ankyrin binding	3/3891	19/18639	0.157894736842105	0.756360832690825	0.790665303428651	1
GO:0042800	histone H3K4 methyltransferase activity	3/3891	19/18639	0.157894736842105	0.756360832690825	0.790665303428651	1
GO:0045505	dynein intermediate chain binding	6/3891	36/18639	0.166666666666667	0.798380878951426	0.7921993765067	1
GO:0061733	protein-lysine-acetyltransferase activity	8/3891	47/18639	0.170212765957447	0.815367706163159	0.793775382618314	1
GO:0003707	nuclear steroid receptor activity	4/3891	25/18639	0.16	0.766445643793369	0.797279789313321	1
GO:0005537	D-mannose binding	4/3891	25/18639	0.16	0.766445643793369	0.797279789313321	1
GO:0015662	P-type ion transporter activity	4/3891	25/18639	0.16	0.766445643793369	0.797279789313321	1
GO:0140358	P-type transmembrane transporter activity	4/3891	25/18639	0.16	0.766445643793369	0.797279789313321	1
GO:0061980	regulatory RNA binding	10/3891	58/18639	0.172413793103448	0.825911254087683	0.798076012295151	1
GO:0004402	histone acetyltransferase activity	7/3891	42/18639	0.166666666666667	0.798380878951426	0.803007688647979	1
GO:0008307	structural constituent of muscle	7/3891	42/18639	0.166666666666667	0.798380878951426	0.803007688647979	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	5/3891	31/18639	0.161290322580645	0.772626657049767	0.805507183737825	1
GO:0017147	Wnt-protein binding	5/3891	31/18639	0.161290322580645	0.772626657049767	0.805507183737825	1
GO:0043394	proteoglycan binding	6/3891	37/18639	0.162162162162162	0.776803017358145	0.814174964986364	1
GO:0001614	purinergic nucleotide receptor activity	3/3891	20/18639	0.15	0.718542791056284	0.819724134129889	1
GO:0001972	retinoic acid binding	3/3891	20/18639	0.15	0.718542791056284	0.819724134129889	1
GO:0015095	magnesium ion transmembrane transporter activity	3/3891	20/18639	0.15	0.718542791056284	0.819724134129889	1
GO:0016502	nucleotide receptor activity	3/3891	20/18639	0.15	0.718542791056284	0.819724134129889	1
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	3/3891	20/18639	0.15	0.718542791056284	0.819724134129889	1
GO:0061608	nuclear import signal receptor activity	3/3891	20/18639	0.15	0.718542791056284	0.819724134129889	1
GO:0005506	iron ion binding	28/3891	154/18639	0.181818181818182	0.870960958856101	0.821999226921151	1
GO:0004435	phosphatidylinositol phospholipase C activity	4/3891	26/18639	0.153846153846154	0.736966965185932	0.822585248387777	1
GO:0030247	polysaccharide binding	4/3891	26/18639	0.153846153846154	0.736966965185932	0.822585248387777	1
GO:0043548	phosphatidylinositol 3-kinase binding	4/3891	26/18639	0.153846153846154	0.736966965185932	0.822585248387777	1
GO:0005545	1-phosphatidylinositol binding	2/3891	14/18639	0.142857142857143	0.684326467672651	0.823152060048965	1
GO:0008191	metalloendopeptidase inhibitor activity	2/3891	14/18639	0.142857142857143	0.684326467672651	0.823152060048965	1
GO:0008195	phosphatidate phosphatase activity	2/3891	14/18639	0.142857142857143	0.684326467672651	0.823152060048965	1
GO:0008494	translation activator activity	2/3891	14/18639	0.142857142857143	0.684326467672651	0.823152060048965	1
GO:0015926	glucosidase activity	2/3891	14/18639	0.142857142857143	0.684326467672651	0.823152060048965	1
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	2/3891	14/18639	0.142857142857143	0.684326467672651	0.823152060048965	1
GO:0042043	neurexin family protein binding	2/3891	14/18639	0.142857142857143	0.684326467672651	0.823152060048965	1
GO:0061665	SUMO ligase activity	2/3891	14/18639	0.142857142857143	0.684326467672651	0.823152060048965	1
GO:0033192	calmodulin-dependent protein phosphatase activity	14/3891	81/18639	0.172839506172839	0.827950541134812	0.82412459858234	1
GO:0140791	histone H2AXS140 phosphatase activity	14/3891	81/18639	0.172839506172839	0.827950541134812	0.82412459858234	1
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	14/3891	81/18639	0.172839506172839	0.827950541134812	0.82412459858234	1
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	14/3891	81/18639	0.172839506172839	0.827950541134812	0.82412459858234	1
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	14/3891	81/18639	0.172839506172839	0.827950541134812	0.82412459858234	1
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	14/3891	81/18639	0.172839506172839	0.827950541134812	0.82412459858234	1
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	14/3891	81/18639	0.172839506172839	0.827950541134812	0.82412459858234	1
GO:1990439	MAP kinase serine/threonine phosphatase activity	14/3891	81/18639	0.172839506172839	0.827950541134812	0.82412459858234	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	5/3891	32/18639	0.15625	0.748482074016962	0.827920672319081	1
GO:0005539	glycosaminoglycan binding	45/3891	242/18639	0.18595041322314	0.890755526102831	0.830776699530786	1
GO:0005004	GPI-linked ephrin receptor activity	8/3891	49/18639	0.163265306122449	0.782087391625887	0.831187556222981	1
GO:0005008	hepatocyte growth factor receptor activity	8/3891	49/18639	0.163265306122449	0.782087391625887	0.831187556222981	1
GO:0005009	insulin receptor activity	8/3891	49/18639	0.163265306122449	0.782087391625887	0.831187556222981	1
GO:0005011	macrophage colony-stimulating factor receptor activity	8/3891	49/18639	0.163265306122449	0.782087391625887	0.831187556222981	1
GO:0005018	platelet-derived growth factor alpha-receptor activity	8/3891	49/18639	0.163265306122449	0.782087391625887	0.831187556222981	1
GO:0005020	stem cell factor receptor activity	8/3891	49/18639	0.163265306122449	0.782087391625887	0.831187556222981	1
GO:0008288	boss receptor activity	8/3891	49/18639	0.163265306122449	0.782087391625887	0.831187556222981	1
GO:0036332	placental growth factor receptor activity	8/3891	49/18639	0.163265306122449	0.782087391625887	0.831187556222981	1
GO:0038062	protein tyrosine kinase collagen receptor activity	8/3891	49/18639	0.163265306122449	0.782087391625887	0.831187556222981	1
GO:0060175	brain-derived neurotrophic factor receptor activity	8/3891	49/18639	0.163265306122449	0.782087391625887	0.831187556222981	1
GO:0004714	transmembrane receptor protein tyrosine kinase activity	10/3891	60/18639	0.166666666666667	0.798380878951426	0.831763423599773	1
GO:0000146	microfilament motor activity	6/3891	38/18639	0.157894736842105	0.756360832690825	0.834277550090188	1
GO:0042887	amide transmembrane transporter activity	6/3891	38/18639	0.157894736842105	0.756360832690825	0.834277550090188	1
GO:0005253	monoatomic anion channel activity	18/3891	103/18639	0.174757281553398	0.837137232298583	0.834538508016541	1
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	14/3891	82/18639	0.170731707317073	0.817853583316095	0.837760091588494	1
GO:0033549	MAP kinase phosphatase activity	14/3891	82/18639	0.170731707317073	0.817853583316095	0.837760091588494	1
GO:0098632	cell-cell adhesion mediator activity	9/3891	55/18639	0.163636363636364	0.783864862970491	0.83923148291323	1
GO:0001223	transcription coactivator binding	7/3891	44/18639	0.159090909090909	0.762090838999089	0.841007031134796	1
GO:0043014	alpha-tubulin binding	7/3891	44/18639	0.159090909090909	0.762090838999089	0.841007031134796	1
GO:0008234	cysteine-type peptidase activity	34/3891	187/18639	0.181818181818182	0.870960958856101	0.841790741449111	1
GO:0005104	fibroblast growth factor receptor binding	4/3891	27/18639	0.148148148148148	0.709671892401268	0.845217520242163	1
GO:0005385	zinc ion transmembrane transporter activity	4/3891	27/18639	0.148148148148148	0.709671892401268	0.845217520242163	1
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	3/3891	21/18639	0.142857142857143	0.684326467672651	0.845269463277529	1
GO:0061891	calcium ion sensor activity	3/3891	21/18639	0.142857142857143	0.684326467672651	0.845269463277529	1
GO:0005006	epidermal growth factor receptor activity	8/3891	50/18639	0.16	0.766445643793369	0.847791438100232	1
GO:0005007	fibroblast growth factor receptor activity	8/3891	50/18639	0.16	0.766445643793369	0.847791438100232	1
GO:0005017	platelet-derived growth factor receptor activity	8/3891	50/18639	0.16	0.766445643793369	0.847791438100232	1
GO:0005019	platelet-derived growth factor beta-receptor activity	8/3891	50/18639	0.16	0.766445643793369	0.847791438100232	1
GO:0042379	chemokine receptor binding	12/3891	72/18639	0.166666666666667	0.798380878951426	0.848131603002558	1
GO:0071889	14-3-3 protein binding	5/3891	33/18639	0.151515151515152	0.725800799046751	0.848186407359177	1
GO:0004467	long-chain fatty acid-CoA ligase activity	2/3891	15/18639	0.133333333333333	0.638704703161141	0.852224401948614	1
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	2/3891	15/18639	0.133333333333333	0.638704703161141	0.852224401948614	1
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	2/3891	15/18639	0.133333333333333	0.638704703161141	0.852224401948614	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/3891	15/18639	0.133333333333333	0.638704703161141	0.852224401948614	1
GO:0010181	FMN binding	2/3891	15/18639	0.133333333333333	0.638704703161141	0.852224401948614	1
GO:0030553	cGMP binding	2/3891	15/18639	0.133333333333333	0.638704703161141	0.852224401948614	1
GO:0034483	heparan sulfate sulfotransferase activity	2/3891	15/18639	0.133333333333333	0.638704703161141	0.852224401948614	1
GO:0048531	beta-1,3-galactosyltransferase activity	2/3891	15/18639	0.133333333333333	0.638704703161141	0.852224401948614	1
GO:0051371	muscle alpha-actinin binding	2/3891	15/18639	0.133333333333333	0.638704703161141	0.852224401948614	1
GO:0120283	protein serine/threonine kinase binding	2/3891	15/18639	0.133333333333333	0.638704703161141	0.852224401948614	1
GO:0140776	protein-containing complex destabilizing activity	2/3891	15/18639	0.133333333333333	0.638704703161141	0.852224401948614	1
GO:0016500	protein-hormone receptor activity	11/3891	67/18639	0.164179104477612	0.786464746429763	0.854188776721855	1
GO:0017018	myosin phosphatase activity	14/3891	84/18639	0.166666666666667	0.798380878951426	0.862603003435891	1
GO:0005010	insulin-like growth factor receptor activity	8/3891	51/18639	0.156862745098039	0.751417297836636	0.863065330192382	1
GO:0005030	neurotrophin receptor activity	8/3891	51/18639	0.156862745098039	0.751417297836636	0.863065330192382	1
GO:1902936	phosphatidylinositol bisphosphate binding	19/3891	111/18639	0.171171171171171	0.819958740544708	0.864348979646913	1
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	4/3891	28/18639	0.142857142857143	0.684326467672651	0.865361391316622	1
GO:0008376	acetylgalactosaminyltransferase activity	5/3891	34/18639	0.147058823529412	0.704453716721847	0.866430954822688	1
GO:0015020	glucuronosyltransferase activity	5/3891	34/18639	0.147058823529412	0.704453716721847	0.866430954822688	1
GO:0015377	chloride:monoatomic cation symporter activity	3/3891	22/18639	0.136363636363636	0.653220719142076	0.867607598599995	1
GO:0032931	histone H3K56 acetyltransferase activity	3/3891	22/18639	0.136363636363636	0.653220719142076	0.867607598599995	1
GO:0043992	histone H3K9 acetyltransferase activity	3/3891	22/18639	0.136363636363636	0.653220719142076	0.867607598599995	1
GO:0043993	histone H3K18 acetyltransferase activity	3/3891	22/18639	0.136363636363636	0.653220719142076	0.867607598599995	1
GO:0043994	histone H3K23 acetyltransferase activity	3/3891	22/18639	0.136363636363636	0.653220719142076	0.867607598599995	1
GO:0043999	histone H2AK5 acetyltransferase activity	3/3891	22/18639	0.136363636363636	0.653220719142076	0.867607598599995	1
GO:0044012	histone H2AK9 acetyltransferase activity	3/3891	22/18639	0.136363636363636	0.653220719142076	0.867607598599995	1
GO:0044014	histone H2BK5 acetyltransferase activity	3/3891	22/18639	0.136363636363636	0.653220719142076	0.867607598599995	1
GO:0044015	histone H2BK12 acetyltransferase activity	3/3891	22/18639	0.136363636363636	0.653220719142076	0.867607598599995	1
GO:0044016	histone H3K4 acetyltransferase activity	3/3891	22/18639	0.136363636363636	0.653220719142076	0.867607598599995	1
GO:0044017	histone H3K27 acetyltransferase activity	3/3891	22/18639	0.136363636363636	0.653220719142076	0.867607598599995	1
GO:0044018	histone H3K36 acetyltransferase activity	3/3891	22/18639	0.136363636363636	0.653220719142076	0.867607598599995	1
GO:0046972	histone H4K16 acetyltransferase activity	3/3891	22/18639	0.136363636363636	0.653220719142076	0.867607598599995	1
GO:0050321	tau-protein kinase activity	3/3891	22/18639	0.136363636363636	0.653220719142076	0.867607598599995	1
GO:0140908	histone H3K122 acetyltransferase activity	3/3891	22/18639	0.136363636363636	0.653220719142076	0.867607598599995	1
GO:0003678	DNA helicase activity	12/3891	74/18639	0.162162162162162	0.776803017358145	0.873180775963445	1
GO:1901682	sulfur compound transmembrane transporter activity	10/3891	63/18639	0.158730158730159	0.760362741858501	0.873949532425919	1
GO:0003688	DNA replication origin binding	2/3891	16/18639	0.125	0.59878565921357	0.876868925023178	1
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	2/3891	16/18639	0.125	0.59878565921357	0.876868925023178	1
GO:0015562	efflux transmembrane transporter activity	2/3891	16/18639	0.125	0.59878565921357	0.876868925023178	1
GO:0005343	organic acid:sodium symporter activity	5/3891	35/18639	0.142857142857143	0.684326467672651	0.882789300786899	1
GO:0005416	amino acid:monoatomic cation symporter activity	4/3891	29/18639	0.137931034482759	0.660729003270146	0.883210521434529	1
GO:0043236	laminin binding	4/3891	29/18639	0.137931034482759	0.660729003270146	0.883210521434529	1
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	4/3891	29/18639	0.137931034482759	0.660729003270146	0.883210521434529	1
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	14/3891	86/18639	0.162790697674419	0.77981388176651	0.884365066754367	1
GO:0003725	double-stranded RNA binding	12/3891	75/18639	0.16	0.766445643793369	0.884405150593754	1
GO:0003887	DNA-directed DNA polymerase activity	3/3891	23/18639	0.130434782608696	0.624819818309812	0.887047907708931	1
GO:0044013	histone H2B acetyltransferase activity	3/3891	23/18639	0.130434782608696	0.624819818309812	0.887047907708931	1
GO:0099186	structural constituent of postsynapse	3/3891	23/18639	0.130434782608696	0.624819818309812	0.887047907708931	1
GO:0005003	ephrin receptor activity	8/3891	53/18639	0.150943396226415	0.723061928106952	0.889874004644775	1
GO:0005005	transmembrane-ephrin receptor activity	8/3891	53/18639	0.150943396226415	0.723061928106952	0.889874004644775	1
GO:0008146	sulfotransferase activity	8/3891	53/18639	0.150943396226415	0.723061928106952	0.889874004644775	1
GO:0038064	collagen receptor activity	8/3891	53/18639	0.150943396226415	0.723061928106952	0.889874004644775	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	11/3891	70/18639	0.157142857142857	0.752759114439916	0.890413814029836	1
GO:0097110	scaffold protein binding	11/3891	70/18639	0.157142857142857	0.752759114439916	0.890413814029836	1
GO:0008083	growth factor activity	28/3891	162/18639	0.172839506172839	0.827950541134812	0.892093237030607	1
GO:0015459	potassium channel regulator activity	9/3891	59/18639	0.152542372881356	0.730721482430119	0.893344254927109	1
GO:0070888	E-box binding	9/3891	59/18639	0.152542372881356	0.730721482430119	0.893344254927109	1
GO:0044390	ubiquitin-like protein conjugating enzyme binding	5/3891	36/18639	0.138888888888889	0.665317399126189	0.897400578896609	1
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/3891	17/18639	0.117647058823529	0.563562973377478	0.89766685749983	1
GO:0045236	CXCR chemokine receptor binding	2/3891	17/18639	0.117647058823529	0.563562973377478	0.89766685749983	1
GO:0070492	oligosaccharide binding	2/3891	17/18639	0.117647058823529	0.563562973377478	0.89766685749983	1
GO:1990226	histone methyltransferase binding	2/3891	17/18639	0.117647058823529	0.563562973377478	0.89766685749983	1
GO:0019894	kinesin binding	6/3891	42/18639	0.142857142857143	0.684326467672651	0.897774344745245	1
GO:0035925	mRNA 3'-UTR AU-rich region binding	4/3891	30/18639	0.133333333333333	0.638704703161141	0.898960923491018	1
GO:0048019	receptor antagonist activity	4/3891	30/18639	0.133333333333333	0.638704703161141	0.898960923491018	1
GO:0000182	rDNA binding	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0004382	GDP phosphatase activity	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0005337	nucleoside transmembrane transporter activity	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0005522	profilin binding	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0008140	cAMP response element binding protein binding	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0008190	eukaryotic initiation factor 4E binding	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0008519	ammonium channel activity	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0015203	polyamine transmembrane transporter activity	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0015279	store-operated calcium channel activity	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0016427	tRNA (cytidine) methyltransferase activity	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0016713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0031419	cobalamin binding	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0032052	bile acid binding	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0035256	G protein-coupled glutamate receptor binding	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0042975	peroxisome proliferator activated receptor binding	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0043121	neurotrophin binding	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0051378	serotonin binding	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0051880	G-quadruplex DNA binding	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0070739	protein-glutamic acid ligase activity	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0070740	tubulin-glutamic acid ligase activity	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0071723	lipopeptide binding	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0140135	mechanosensitive monoatomic cation channel activity	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:1990763	arrestin family protein binding	1/3891	10/18639	0.1	0.479028527370856	0.903876745257504	1
GO:0019957	C-C chemokine binding	3/3891	24/18639	0.125	0.59878565921357	0.90389283390861	1
GO:0043998	histone H2A acetyltransferase activity	3/3891	24/18639	0.125	0.59878565921357	0.90389283390861	1
GO:0070300	phosphatidic acid binding	3/3891	24/18639	0.125	0.59878565921357	0.90389283390861	1
GO:0042805	actinin binding	5/3891	37/18639	0.135135135135135	0.647335847798454	0.910404581070085	1
GO:0008327	methyl-CpG binding	4/3891	31/18639	0.129032258064516	0.618101325639814	0.912805921972972	1
GO:0047499	calcium-independent phospholipase A2 activity	4/3891	31/18639	0.129032258064516	0.618101325639814	0.912805921972972	1
GO:0072349	modified amino acid transmembrane transporter activity	4/3891	31/18639	0.129032258064516	0.618101325639814	0.912805921972972	1
GO:0004970	glutamate-gated receptor activity	2/3891	18/18639	0.111111111111111	0.532253919300951	0.915149777453495	1
GO:0034185	apolipoprotein binding	2/3891	18/18639	0.111111111111111	0.532253919300951	0.915149777453495	1
GO:0050811	GABA receptor binding	2/3891	18/18639	0.111111111111111	0.532253919300951	0.915149777453495	1
GO:0001664	G protein-coupled receptor binding	53/3891	297/18639	0.178451178451178	0.854832052210618	0.916278040196751	1
GO:0000030	mannosyltransferase activity	3/3891	25/18639	0.12	0.574834232845027	0.918430976353422	1
GO:0015271	outward rectifier potassium channel activity	3/3891	25/18639	0.12	0.574834232845027	0.918430976353422	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	3/3891	25/18639	0.12	0.574834232845027	0.918430976353422	1
GO:0015645	fatty acid ligase activity	3/3891	25/18639	0.12	0.574834232845027	0.918430976353422	1
GO:0017056	structural constituent of nuclear pore	3/3891	25/18639	0.12	0.574834232845027	0.918430976353422	1
GO:0042974	nuclear retinoic acid receptor binding	3/3891	25/18639	0.12	0.574834232845027	0.918430976353422	1
GO:0120515	fatty acid-CoA ligase activity	3/3891	25/18639	0.12	0.574834232845027	0.918430976353422	1
GO:0030547	signaling receptor inhibitor activity	6/3891	44/18639	0.136363636363636	0.653220719142076	0.920814373918269	1
GO:0002162	dystroglycan binding	1/3891	11/18639	0.0909090909090909	0.435480479428051	0.923953807053792	1
GO:0004016	adenylate cyclase activity	1/3891	11/18639	0.0909090909090909	0.435480479428051	0.923953807053792	1
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/3891	11/18639	0.0909090909090909	0.435480479428051	0.923953807053792	1
GO:0008271	secondary active sulfate transmembrane transporter activity	1/3891	11/18639	0.0909090909090909	0.435480479428051	0.923953807053792	1
GO:0015173	aromatic amino acid transmembrane transporter activity	1/3891	11/18639	0.0909090909090909	0.435480479428051	0.923953807053792	1
GO:0016594	glycine binding	1/3891	11/18639	0.0909090909090909	0.435480479428051	0.923953807053792	1
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	1/3891	11/18639	0.0909090909090909	0.435480479428051	0.923953807053792	1
GO:0034056	estrogen response element binding	1/3891	11/18639	0.0909090909090909	0.435480479428051	0.923953807053792	1
GO:0043522	leucine zipper domain binding	1/3891	11/18639	0.0909090909090909	0.435480479428051	0.923953807053792	1
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/3891	11/18639	0.0909090909090909	0.435480479428051	0.923953807053792	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/3891	11/18639	0.0909090909090909	0.435480479428051	0.923953807053792	1
GO:0047498	calcium-dependent phospholipase A2 activity	4/3891	32/18639	0.125	0.59878565921357	0.924932386209242	1
GO:0016298	lipase activity	21/3891	130/18639	0.161538461538462	0.773815313445229	0.928362792149573	1
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	2/3891	19/18639	0.105263157894737	0.504240555127217	0.929795009691712	1
GO:0005229	intracellularly calcium-gated chloride channel activity	2/3891	19/18639	0.105263157894737	0.504240555127217	0.929795009691712	1
GO:0042577	lipid phosphatase activity	2/3891	19/18639	0.105263157894737	0.504240555127217	0.929795009691712	1
GO:0046624	sphingolipid transporter activity	2/3891	19/18639	0.105263157894737	0.504240555127217	0.929795009691712	1
GO:0141147	intracellularly calcium-gated channel activity	2/3891	19/18639	0.105263157894737	0.504240555127217	0.929795009691712	1
GO:1990380	K48-linked deubiquitinase activity	2/3891	19/18639	0.105263157894737	0.504240555127217	0.929795009691712	1
GO:0001637	G protein-coupled chemoattractant receptor activity	3/3891	26/18639	0.115384615384615	0.552725223889449	0.930932593044593	1
GO:0004950	chemokine receptor activity	3/3891	26/18639	0.115384615384615	0.552725223889449	0.930932593044593	1
GO:0004126	cytidine deaminase activity	1/3891	12/18639	0.0833333333333333	0.399190439475713	0.939838267905934	1
GO:0004859	phospholipase inhibitor activity	1/3891	12/18639	0.0833333333333333	0.399190439475713	0.939838267905934	1
GO:0005078	MAP-kinase scaffold activity	1/3891	12/18639	0.0833333333333333	0.399190439475713	0.939838267905934	1
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	1/3891	12/18639	0.0833333333333333	0.399190439475713	0.939838267905934	1
GO:0008603	cAMP-dependent protein kinase regulator activity	1/3891	12/18639	0.0833333333333333	0.399190439475713	0.939838267905934	1
GO:0015132	prostaglandin transmembrane transporter activity	1/3891	12/18639	0.0833333333333333	0.399190439475713	0.939838267905934	1
GO:0070410	co-SMAD binding	1/3891	12/18639	0.0833333333333333	0.399190439475713	0.939838267905934	1
GO:0004683	calcium/calmodulin-dependent protein kinase activity	3/3891	27/18639	0.111111111111111	0.532253919300951	0.941646977144897	1
GO:0016405	CoA-ligase activity	3/3891	27/18639	0.111111111111111	0.532253919300951	0.941646977144897	1
GO:0019783	ubiquitin-like protein peptidase activity	20/3891	127/18639	0.15748031496063	0.754375633654891	0.941809299148947	1
GO:0005326	neurotransmitter transmembrane transporter activity	2/3891	20/18639	0.1	0.479028527370856	0.94202510697636	1
GO:0051427	hormone receptor binding	4/3891	34/18639	0.117647058823529	0.563562973377478	0.944729649616655	1
GO:0004879	nuclear receptor activity	8/3891	59/18639	0.135593220338983	0.64953020660455	0.945343399587631	1
GO:0051018	protein kinase A binding	7/3891	53/18639	0.132075471698113	0.632679187093583	0.945716058298934	1
GO:0140359	ABC-type transporter activity	6/3891	47/18639	0.127659574468085	0.611525779622369	0.946842708041422	1
GO:0005254	chloride channel activity	12/3891	83/18639	0.144578313253012	0.692571364873526	0.947974424294008	1
GO:0140375	immune receptor activity	25/3891	156/18639	0.16025641025641	0.767673922068679	0.948436206079001	1
GO:0004812	aminoacyl-tRNA ligase activity	5/3891	41/18639	0.121951219512195	0.584181130940068	0.949028188010557	1
GO:0008227	G protein-coupled amine receptor activity	5/3891	41/18639	0.121951219512195	0.584181130940068	0.949028188010557	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	5/3891	41/18639	0.121951219512195	0.584181130940068	0.949028188010557	1
GO:0005319	lipid transporter activity	29/3891	178/18639	0.162921348314607	0.780439735604203	0.949157042899436	1
GO:0005242	inward rectifier potassium channel activity	3/3891	28/18639	0.107142857142857	0.513244850754488	0.95080124744429	1
GO:0050698	proteoglycan sulfotransferase activity	3/3891	28/18639	0.107142857142857	0.513244850754488	0.95080124744429	1
GO:0051393	alpha-actinin binding	3/3891	28/18639	0.107142857142857	0.513244850754488	0.95080124744429	1
GO:0061135	endopeptidase regulator activity	30/3891	184/18639	0.16304347826087	0.781024772887265	0.951275064891597	1
GO:0098531	ligand-modulated transcription factor activity	8/3891	60/18639	0.133333333333333	0.638704703161141	0.95167139022335	1
GO:0005248	voltage-gated sodium channel activity	2/3891	21/18639	0.0952380952380952	0.456217645115101	0.952209911576236	1
GO:0015125	bile acid transmembrane transporter activity	2/3891	21/18639	0.0952380952380952	0.456217645115101	0.952209911576236	1
GO:0035613	RNA stem-loop binding	2/3891	21/18639	0.0952380952380952	0.456217645115101	0.952209911576236	1
GO:0036122	BMP binding	2/3891	21/18639	0.0952380952380952	0.456217645115101	0.952209911576236	1
GO:0051428	peptide hormone receptor binding	2/3891	21/18639	0.0952380952380952	0.456217645115101	0.952209911576236	1
GO:0004535	poly(A)-specific ribonuclease activity	1/3891	13/18639	0.0769230769230769	0.368483482592966	0.952405471405049	1
GO:0004993	G protein-coupled serotonin receptor activity	1/3891	13/18639	0.0769230769230769	0.368483482592966	0.952405471405049	1
GO:0031994	insulin-like growth factor I binding	1/3891	13/18639	0.0769230769230769	0.368483482592966	0.952405471405049	1
GO:0043560	insulin receptor substrate binding	1/3891	13/18639	0.0769230769230769	0.368483482592966	0.952405471405049	1
GO:0061459	L-arginine transmembrane transporter activity	1/3891	13/18639	0.0769230769230769	0.368483482592966	0.952405471405049	1
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/3891	13/18639	0.0769230769230769	0.368483482592966	0.952405471405049	1
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/3891	13/18639	0.0769230769230769	0.368483482592966	0.952405471405049	1
GO:1901338	catecholamine binding	1/3891	13/18639	0.0769230769230769	0.368483482592966	0.952405471405049	1
GO:0004623	phospholipase A2 activity	4/3891	35/18639	0.114285714285714	0.547461174138121	0.952721952691462	1
GO:0042277	peptide binding	42/3891	249/18639	0.168674698795181	0.807999925685781	0.952923800398843	1
GO:0035173	histone kinase activity	63/3891	360/18639	0.175	0.838299922898998	0.953566132974766	1
GO:0106310	protein serine kinase activity	63/3891	361/18639	0.174515235457064	0.835977762447754	0.956054069955678	1
GO:0015171	amino acid transmembrane transporter activity	15/3891	102/18639	0.147058823529412	0.704453716721847	0.956367072023488	1
GO:0003774	cytoskeletal motor activity	24/3891	153/18639	0.156862745098039	0.751417297836636	0.957934285692126	1
GO:0106222	lncRNA binding	3/3891	29/18639	0.103448275862069	0.495546752452609	0.958600177368492	1
GO:0140996	histone H3 kinase activity	62/3891	357/18639	0.173669467787115	0.831926294033419	0.958995899340213	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	4/3891	36/18639	0.111111111111111	0.532253919300951	0.959637124415819	1
GO:0008970	phospholipase A1 activity	2/3891	22/18639	0.0909090909090909	0.435480479428051	0.960670142873861	1
GO:0003777	microtubule motor activity	9/3891	68/18639	0.132352941176471	0.634008345049662	0.961927133535056	1
GO:0005548	phospholipid transporter activity	9/3891	68/18639	0.132352941176471	0.634008345049662	0.961927133535056	1
GO:0008331	high voltage-gated calcium channel activity	1/3891	14/18639	0.0714285714285714	0.342163233836326	0.962348041509363	1
GO:0015386	potassium:proton antiporter activity	1/3891	14/18639	0.0714285714285714	0.342163233836326	0.962348041509363	1
GO:0019992	diacylglycerol binding	1/3891	14/18639	0.0714285714285714	0.342163233836326	0.962348041509363	1
GO:0032454	histone H3K9 demethylase activity	1/3891	14/18639	0.0714285714285714	0.342163233836326	0.962348041509363	1
GO:0042813	Wnt receptor activity	1/3891	14/18639	0.0714285714285714	0.342163233836326	0.962348041509363	1
GO:0043176	amine binding	1/3891	14/18639	0.0714285714285714	0.342163233836326	0.962348041509363	1
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	1/3891	14/18639	0.0714285714285714	0.342163233836326	0.962348041509363	1
GO:0070742	C2H2 zinc finger domain binding	1/3891	14/18639	0.0714285714285714	0.342163233836326	0.962348041509363	1
GO:0101005	deubiquitinase activity	17/3891	115/18639	0.147826086956522	0.708129127417787	0.96255093748705	1
GO:0008509	monoatomic anion transmembrane transporter activity	23/3891	149/18639	0.154362416107383	0.739440008693267	0.963119152842469	1
GO:0170055	lipid transmembrane transporter activity	7/3891	56/18639	0.125	0.59878565921357	0.963347395443827	1
GO:0046943	carboxylic acid transmembrane transporter activity	30/3891	188/18639	0.159574468085106	0.764407224527962	0.964037372038592	1
GO:0004674	protein serine/threonine kinase activity	76/3891	433/18639	0.175519630484988	0.840789101159008	0.964711667573219	1
GO:0048020	CCR chemokine receptor binding	6/3891	50/18639	0.12	0.574834232845027	0.964912557666876	1
GO:0031624	ubiquitin conjugating enzyme binding	3/3891	30/18639	0.1	0.479028527370856	0.965226761132656	1
GO:0098918	structural constituent of synapse	3/3891	30/18639	0.1	0.479028527370856	0.965226761132656	1
GO:0030551	cyclic nucleotide binding	4/3891	37/18639	0.108108108108108	0.517868678238763	0.965604705427423	1
GO:0015101	organic cation transmembrane transporter activity	11/3891	81/18639	0.135802469135802	0.650532568034496	0.966077234217878	1
GO:0005342	organic acid transmembrane transporter activity	30/3891	189/18639	0.158730158730159	0.760362741858501	0.966733784095641	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	2/3891	23/18639	0.0869565217391304	0.416546545539875	0.96768178431814	1
GO:0016493	C-C chemokine receptor activity	2/3891	23/18639	0.0869565217391304	0.416546545539875	0.96768178431814	1
GO:0031490	chromatin DNA binding	19/3891	128/18639	0.1484375	0.711057970316114	0.967851751836748	1
GO:0016597	amino acid binding	6/3891	51/18639	0.117647058823529	0.563562973377478	0.969555187915692	1
GO:0005125	cytokine activity	38/3891	234/18639	0.162393162393162	0.777909574362928	0.969867168863085	1
GO:0004089	carbonate dehydratase activity	1/3891	15/18639	0.0666666666666667	0.319352351580571	0.970214015763702	1
GO:0008242	omega peptidase activity	1/3891	15/18639	0.0666666666666667	0.319352351580571	0.970214015763702	1
GO:0015116	sulfate transmembrane transporter activity	1/3891	15/18639	0.0666666666666667	0.319352351580571	0.970214015763702	1
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/3891	15/18639	0.0666666666666667	0.319352351580571	0.970214015763702	1
GO:0047372	monoacylglycerol lipase activity	1/3891	15/18639	0.0666666666666667	0.319352351580571	0.970214015763702	1
GO:0000149	SNARE binding	15/3891	106/18639	0.141509433962264	0.677870557600268	0.970955245301375	1
GO:0001217	DNA-binding transcription repressor activity	46/3891	278/18639	0.165467625899281	0.79263713162084	0.971480634616784	1
GO:0005200	structural constituent of cytoskeleton	16/3891	112/18639	0.142857142857143	0.684326467672651	0.97149985168062	1
GO:0140303	intramembrane lipid transporter activity	5/3891	45/18639	0.111111111111111	0.532253919300951	0.971887049137445	1
GO:0016758	hexosyltransferase activity	31/3891	197/18639	0.157360406091371	0.753801235964291	0.972668677206685	1
GO:0004806	triacylglycerol lipase activity	2/3891	24/18639	0.0833333333333333	0.399190439475713	0.973480779809915	1
GO:0005315	phosphate transmembrane transporter activity	2/3891	24/18639	0.0833333333333333	0.399190439475713	0.973480779809915	1
GO:0141003	histone H2AX kinase activity	60/3891	354/18639	0.169491525423729	0.811912758255688	0.97365136253579	1
GO:0035402	histone H3T11 kinase activity	40/3891	247/18639	0.161943319838057	0.775754700195718	0.974167224378564	1
GO:0035403	histone H3T6 kinase activity	40/3891	247/18639	0.161943319838057	0.775754700195718	0.974167224378564	1
GO:0015385	sodium:proton antiporter activity	1/3891	16/18639	0.0625	0.299392829606785	0.97643702181307	1
GO:0022858	alanine transmembrane transporter activity	1/3891	16/18639	0.0625	0.299392829606785	0.97643702181307	1
GO:0055102	lipase inhibitor activity	1/3891	16/18639	0.0625	0.299392829606785	0.97643702181307	1
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/3891	16/18639	0.0625	0.299392829606785	0.97643702181307	1
GO:0140328	floppase activity	1/3891	16/18639	0.0625	0.299392829606785	0.97643702181307	1
GO:0005251	delayed rectifier potassium channel activity	2/3891	25/18639	0.08	0.383222821896685	0.978267719240914	1
GO:0047617	fatty acyl-CoA hydrolase activity	2/3891	25/18639	0.08	0.383222821896685	0.978267719240914	1
GO:0015108	chloride transmembrane transporter activity	17/3891	121/18639	0.140495867768595	0.673015286388806	0.97941784803771	1
GO:0004676	3-phosphoinositide-dependent protein kinase activity	39/3891	245/18639	0.159183673469388	0.76253520683524	0.979960942366766	1
GO:0004711	ribosomal protein S6 kinase activity	39/3891	245/18639	0.159183673469388	0.76253520683524	0.979960942366766	1
GO:0035175	histone H3S10 kinase activity	39/3891	245/18639	0.159183673469388	0.76253520683524	0.979960942366766	1
GO:0035979	histone H2AXS139 kinase activity	39/3891	245/18639	0.159183673469388	0.76253520683524	0.979960942366766	1
GO:0044022	histone H3S28 kinase activity	39/3891	245/18639	0.159183673469388	0.76253520683524	0.979960942366766	1
GO:0044023	histone H4S1 kinase activity	39/3891	245/18639	0.159183673469388	0.76253520683524	0.979960942366766	1
GO:0044024	histone H2AS1 kinase activity	39/3891	245/18639	0.159183673469388	0.76253520683524	0.979960942366766	1
GO:0044025	histone H2BS14 kinase activity	39/3891	245/18639	0.159183673469388	0.76253520683524	0.979960942366766	1
GO:0072354	histone H3T3 kinase activity	39/3891	245/18639	0.159183673469388	0.76253520683524	0.979960942366766	1
GO:0072371	histone H2AS121 kinase activity	39/3891	245/18639	0.159183673469388	0.76253520683524	0.979960942366766	1
GO:0072518	Rho-dependent protein serine/threonine kinase activity	39/3891	245/18639	0.159183673469388	0.76253520683524	0.979960942366766	1
GO:0140823	histone H2BS36 kinase activity	39/3891	245/18639	0.159183673469388	0.76253520683524	0.979960942366766	1
GO:0140855	histone H3S57 kinase activity	39/3891	245/18639	0.159183673469388	0.76253520683524	0.979960942366766	1
GO:0140995	histone H2A kinase activity	39/3891	245/18639	0.159183673469388	0.76253520683524	0.979960942366766	1
GO:0140997	histone H4 kinase activity	39/3891	245/18639	0.159183673469388	0.76253520683524	0.979960942366766	1
GO:0140998	histone H2B kinase activity	39/3891	245/18639	0.159183673469388	0.76253520683524	0.979960942366766	1
GO:1990244	histone H2AT120 kinase activity	39/3891	245/18639	0.159183673469388	0.76253520683524	0.979960942366766	1
GO:0004222	metalloendopeptidase activity	15/3891	110/18639	0.136363636363636	0.653220719142076	0.981020522946663	1
GO:0008569	minus-end-directed microtubule motor activity	1/3891	17/18639	0.0588235294117647	0.281781486688739	0.981360157082648	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/3891	17/18639	0.0588235294117647	0.281781486688739	0.981360157082648	1
GO:0045125	bioactive lipid receptor activity	1/3891	17/18639	0.0588235294117647	0.281781486688739	0.981360157082648	1
GO:0004677	DNA-dependent protein kinase activity	39/3891	246/18639	0.158536585365854	0.759435470222088	0.981414208303973	1
GO:0140857	histone H3T45 kinase activity	39/3891	246/18639	0.158536585365854	0.759435470222088	0.981414208303973	1
GO:0005112	Notch binding	2/3891	26/18639	0.0769230769230769	0.368483482592966	0.982212313090608	1
GO:0005227	calcium-activated cation channel activity	2/3891	26/18639	0.0769230769230769	0.368483482592966	0.982212313090608	1
GO:0008066	glutamate receptor activity	2/3891	26/18639	0.0769230769230769	0.368483482592966	0.982212313090608	1
GO:0016289	acyl-CoA hydrolase activity	2/3891	26/18639	0.0769230769230769	0.368483482592966	0.982212313090608	1
GO:0051139	metal cation:proton antiporter activity	2/3891	26/18639	0.0769230769230769	0.368483482592966	0.982212313090608	1
GO:0019825	oxygen binding	3/3891	34/18639	0.0882352941176471	0.422672230033108	0.982974711012434	1
GO:0015297	antiporter activity	19/3891	135/18639	0.140740740740741	0.674188297781205	0.983772284051606	1
GO:0004679	AMP-activated protein kinase activity	39/3891	248/18639	0.157258064516129	0.753310990623523	0.984042552810384	1
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	38/3891	243/18639	0.156378600823045	0.749098108645783	0.984667910843367	1
GO:0022851	GABA-gated chloride ion channel activity	1/3891	18/18639	0.0555555555555556	0.266126959650475	0.985254885296128	1
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	2/3891	27/18639	0.0740740740740741	0.354835946200634	0.985457539966265	1
GO:0034061	DNA polymerase activity	3/3891	35/18639	0.0857142857142857	0.410595880603591	0.985810907105025	1
GO:0005245	voltage-gated calcium channel activity	4/3891	43/18639	0.0930232558139535	0.445607932438005	0.987277484714789	1
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	42/3891	268/18639	0.156716417910448	0.750716348864774	0.987769574928091	1
GO:0004843	cysteine-type deubiquitinase activity	14/3891	108/18639	0.12962962962963	0.620962905851109	0.987875575554471	1
GO:0141052	histone H3 demethylase activity	2/3891	28/18639	0.0714285714285714	0.342163233836326	0.988123408621801	1
GO:0004896	cytokine receptor activity	12/3891	96/18639	0.125	0.59878565921357	0.988224728114477	1
GO:0004890	GABA-A receptor activity	1/3891	19/18639	0.0526315789473684	0.252120277563608	0.988335989496373	1
GO:0005520	insulin-like growth factor binding	1/3891	19/18639	0.0526315789473684	0.252120277563608	0.988335989496373	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/3891	19/18639	0.0526315789473684	0.252120277563608	0.988335989496373	1
GO:0022821	solute:potassium antiporter activity	1/3891	19/18639	0.0526315789473684	0.252120277563608	0.988335989496373	1
GO:0031420	alkali metal ion binding	1/3891	19/18639	0.0526315789473684	0.252120277563608	0.988335989496373	1
GO:0034987	immunoglobulin receptor binding	1/3891	19/18639	0.0526315789473684	0.252120277563608	0.988335989496373	1
GO:0042834	peptidoglycan binding	1/3891	19/18639	0.0526315789473684	0.252120277563608	0.988335989496373	1
GO:0099589	serotonin receptor activity	1/3891	19/18639	0.0526315789473684	0.252120277563608	0.988335989496373	1
GO:0008514	organic anion transmembrane transporter activity	42/3891	269/18639	0.156133828996283	0.747925581768622	0.988676005351163	1
GO:0140767	enzyme-substrate adaptor activity	19/3891	139/18639	0.136690647482014	0.654787195686781	0.989250080760788	1
GO:0046982	protein heterodimerization activity	60/3891	369/18639	0.16260162601626	0.778908174586757	0.989963669577091	1
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	16/3891	122/18639	0.131147540983607	0.62823413425686	0.990240031609659	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/3891	20/18639	0.05	0.239514263685428	0.990773404365847	1
GO:0030627	pre-mRNA 5'-splice site binding	1/3891	20/18639	0.05	0.239514263685428	0.990773404365847	1
GO:0022839	monoatomic ion-gated channel activity	2/3891	30/18639	0.0666666666666667	0.319352351580571	0.992101997033987	1
GO:0032452	histone demethylase activity	2/3891	30/18639	0.0666666666666667	0.319352351580571	0.992101997033987	1
GO:0015174	basic amino acid transmembrane transporter activity	1/3891	21/18639	0.0476190476190476	0.22810882255755	0.992701579005328	1
GO:0005516	calmodulin binding	30/3891	207/18639	0.144927536231884	0.694244242566458	0.992813530178649	1
GO:0005184	neuropeptide hormone activity	2/3891	31/18639	0.0645161290322581	0.309050662819907	0.993568115476741	1
GO:0140457	protein demethylase activity	2/3891	31/18639	0.0645161290322581	0.309050662819907	0.993568115476741	1
GO:0099095	ligand-gated monoatomic anion channel activity	4/3891	47/18639	0.0851063829787234	0.407683853081579	0.993626733261519	1
GO:0005243	gap junction channel activity	1/3891	22/18639	0.0454545454545455	0.217740239714025	0.994226885487779	1
GO:0032451	demethylase activity	3/3891	40/18639	0.075	0.359271395528142	0.994400879131504	1
GO:0071855	neuropeptide receptor binding	3/3891	40/18639	0.075	0.359271395528142	0.994400879131504	1
GO:0015106	bicarbonate transmembrane transporter activity	2/3891	32/18639	0.0625	0.299392829606785	0.994766477683186	1
GO:0160041	neuropeptide activity	2/3891	32/18639	0.0625	0.299392829606785	0.994766477683186	1
GO:0015294	solute:monoatomic cation symporter activity	14/3891	116/18639	0.120689655172414	0.578137877861378	0.995344705641	1
GO:0005212	structural constituent of eye lens	1/3891	23/18639	0.0434782608695652	0.208273272769937	0.995433480995489	1
GO:0016917	GABA receptor activity	1/3891	23/18639	0.0434782608695652	0.208273272769937	0.995433480995489	1
GO:0015103	inorganic anion transmembrane transporter activity	22/3891	165/18639	0.133333333333333	0.638704703161141	0.995471201782999	1
GO:0030296	protein tyrosine kinase activator activity	2/3891	33/18639	0.0606060606060606	0.290320319618701	0.995744950645222	1
GO:0030552	cAMP binding	1/3891	24/18639	0.0416666666666667	0.199595219737857	0.996387946264428	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	2/3891	34/18639	0.0588235294117647	0.281781486688739	0.996543090622271	1
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	78/3891	484/18639	0.161157024793388	0.771988122622454	0.996927845234484	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	24/3891	181/18639	0.132596685082873	0.635175947895057	0.997057150164088	1
GO:0008139	nuclear localization sequence binding	1/3891	25/18639	0.04	0.191611410948342	0.997142955723741	1
GO:0001216	DNA-binding transcription activator activity	79/3891	491/18639	0.160896130346232	0.770738363794249	0.997239093295714	1
GO:0015293	symporter activity	18/3891	146/18639	0.123287671232877	0.590583115936671	0.997488497533432	1
GO:0004867	serine-type endopeptidase inhibitor activity	10/3891	95/18639	0.105263157894737	0.504240555127217	0.997535985733703	1
GO:0005544	calcium-dependent phospholipid binding	4/3891	53/18639	0.0754716981132075	0.361530964053476	0.997816574722827	1
GO:0030280	structural constituent of skin epidermis	2/3891	37/18639	0.0540540540540541	0.258934339119382	0.998153978358599	1
GO:0008395	steroid hydroxylase activity	1/3891	27/18639	0.037037037037037	0.177417973100317	0.998212590716097	1
GO:0030414	peptidase inhibitor activity	21/3891	169/18639	0.124260355029586	0.595242548804022	0.998513244588138	1
GO:0042562	hormone binding	9/3891	94/18639	0.0957446808510638	0.458644334716777	0.998950519897905	1
GO:0004175	endopeptidase activity	61/3891	405/18639	0.150617283950617	0.721499757274622	0.998957791982837	1
GO:0015291	secondary active transmembrane transporter activity	40/3891	287/18639	0.139372822299652	0.667635578217221	0.999097385766772	1
GO:0004866	endopeptidase inhibitor activity	19/3891	161/18639	0.118012422360248	0.565313168946973	0.999123297112672	1
GO:0140828	metal cation:monoatomic cation antiporter activity	2/3891	41/18639	0.0487804878048781	0.233672452376027	0.999206998581704	1
GO:0022832	voltage-gated channel activity	21/3891	175/18639	0.12	0.574834232845027	0.999264863298489	1
GO:0005272	sodium channel activity	3/3891	51/18639	0.0588235294117647	0.281781486688739	0.999335811530625	1
GO:0005262	calcium channel activity	14/3891	131/18639	0.106870229007634	0.511938884213128	0.999337907331864	1
GO:0005249	voltage-gated potassium channel activity	9/3891	98/18639	0.0918367346938776	0.439924157789562	0.999431585855475	1
GO:0017046	peptide hormone binding	3/3891	53/18639	0.0566037735849057	0.271148223040107	0.999553692610258	1
GO:0005244	voltage-gated monoatomic ion channel activity	20/3891	173/18639	0.115606936416185	0.553790205053012	0.999564384027765	1
GO:0005216	monoatomic ion channel activity	66/3891	448/18639	0.147321428571429	0.705711669787422	0.999691921773147	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	2/3891	46/18639	0.0434782608695652	0.208273272769937	0.999727348012417	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	3/3891	56/18639	0.0535714285714286	0.256622425377244	0.999755318019402	1
GO:0004190	aspartic-type endopeptidase activity	1/3891	36/18639	0.0277777777777778	0.133063479825238	0.999783578541616	1
GO:0015085	calcium ion transmembrane transporter activity	15/3891	147/18639	0.102040816326531	0.488804619766179	0.999817556650983	1
GO:0070001	aspartic-type peptidase activity	1/3891	37/18639	0.027027027027027	0.129467169559691	0.999828845213366	1
GO:0005267	potassium channel activity	11/3891	124/18639	0.0887096774193548	0.424944661377372	0.999908329902759	1
GO:0015370	solute:sodium symporter activity	5/3891	79/18639	0.0632911392405063	0.303182612260035	0.999919052531106	1
GO:0005261	monoatomic cation channel activity	45/3891	341/18639	0.131964809384164	0.632149083040719	0.999919636811276	1
GO:0015079	potassium ion transmembrane transporter activity	16/3891	160/18639	0.1	0.479028527370856	0.999924231752061	1
GO:0008236	serine-type peptidase activity	21/3891	194/18639	0.108247422680412	0.518536034782885	0.999932049703121	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	2/3891	53/18639	0.0377358490566038	0.180765482026738	0.999939882296242	1
GO:0022824	transmitter-gated monoatomic ion channel activity	3/3891	63/18639	0.0476190476190476	0.22810882255755	0.999940962041423	1
GO:0022835	transmitter-gated channel activity	3/3891	63/18639	0.0476190476190476	0.22810882255755	0.999940962041423	1
GO:0030594	neurotransmitter receptor activity	7/3891	97/18639	0.0721649484536082	0.345690689855257	0.999942369269909	1
GO:0004497	monooxygenase activity	8/3891	106/18639	0.0754716981132075	0.361530964053476	0.999953528059033	1
GO:0022843	voltage-gated monoatomic cation channel activity	13/3891	143/18639	0.0909090909090909	0.435480479428051	0.999956035018703	1
GO:0099094	ligand-gated monoatomic cation channel activity	12/3891	136/18639	0.0882352941176471	0.422672230033108	0.999956750254017	1
GO:0017171	serine hydrolase activity	21/3891	198/18639	0.106060606060606	0.508060559332726	0.999959919152031	1
GO:0004252	serine-type endopeptidase activity	17/3891	176/18639	0.0965909090909091	0.462698009392304	0.999979536172459	1
GO:0098960	postsynaptic neurotransmitter receptor activity	3/3891	69/18639	0.0434782608695652	0.208273272769937	0.99998286430387	1
GO:0001653	peptide receptor activity	10/3891	128/18639	0.078125	0.374241037008481	0.999985156619605	1
GO:0015276	ligand-gated monoatomic ion channel activity	18/3891	186/18639	0.0967741935483871	0.46357599422986	0.999986970167601	1
GO:0022834	ligand-gated channel activity	18/3891	188/18639	0.0957446808510638	0.458644334716777	0.999990226382939	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	3/3891	73/18639	0.0410958904109589	0.196861038645557	0.999992548122351	1
GO:0008528	G protein-coupled peptide receptor activity	8/3891	122/18639	0.0655737704918033	0.31411706712843	0.999997165021593	1
GO:0022836	gated channel activity	36/3891	318/18639	0.113207547169811	0.542296446080214	0.999997870826713	1
GO:0005179	hormone activity	9/3891	132/18639	0.0681818181818182	0.326610359571038	0.999998000525061	1
GO:0003823	antigen binding	13/3891	174/18639	0.0747126436781609	0.357894876771329	0.999999687921441	1
GO:0015081	sodium ion transmembrane transporter activity	10/3891	164/18639	0.0609756097560976	0.292090565470034	0.999999971824694	1
GO:0003730	mRNA 3'-UTR binding	21/3891	262/18639	0.0801526717557252	0.383954163159846	0.999999996747371	1
GO:0046873	metal ion transmembrane transporter activity	48/3891	450/18639	0.106666666666667	0.510963762528913	0.999999997835525	1
GO:0030527	structural constituent of chromatin	1/3891	98/18639	0.0102040816326531	0.0488804619766179	0.99999999989882	1
GO:0004984	olfactory receptor activity	1/3891	419/18639	0.00238663484486874	0.0114326617510944	1	1
GO:0030371	translation repressor activity	6/3891	329/18639	0.0182370820668693	0.0873608256603384	1	1
GO:0045182	translation regulator activity	12/3891	356/18639	0.0337078651685393	0.161470290125008	1	1