ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0005201 extracellular matrix structural constituent 32/425 168/18639 0.19047619047619 8.35361344537815 1.38239424806677e-20 1.01605977232907e-17 GO:0038024 cargo receptor activity 15/425 65/18639 0.230769230769231 10.1207239819005 1.34185293574494e-11 4.93130953886266e-09 GO:0030020 extracellular matrix structural constituent conferring tensile strength 11/425 44/18639 0.25 10.9641176470588 2.96816584130025e-09 7.27200631118561e-07 GO:0005044 scavenger receptor activity 9/425 27/18639 0.333333333333333 14.6188235294118 4.98768624212553e-09 9.16487346990566e-07 GO:0031720 haptoglobin binding 6/425 10/18639 0.6 26.3138823529412 2.63742771929967e-08 3.87701874737052e-06 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 12/425 68/18639 0.176470588235294 7.73937716262976 3.88632243045599e-08 4.76074497730859e-06 GO:0048407 platelet-derived growth factor binding 6/425 11/18639 0.545454545454545 23.9217112299465 5.69066670953167e-08 5.66796814885073e-06 GO:0009055 electron transfer activity 15/425 116/18639 0.129310344827586 5.6710953346856 6.1692170327627e-08 5.66796814885073e-06 GO:0005539 glycosaminoglycan binding 21/425 242/18639 0.0867768595041322 3.8057267865824 1.81472684521905e-07 1.48202692359556e-05 GO:0005344 oxygen carrier activity 6/425 14/18639 0.428571428571429 18.7956302521008 3.48959615300903e-07 2.56485317246164e-05 GO:0008201 heparin binding 16/425 172/18639 0.0930232558139535 4.07967168262654 2.13761517677281e-06 0.00014283155953891 GO:0019838 growth factor binding 14/425 136/18639 0.102941176470588 4.51463667820069 2.81238611196581e-06 0.000172258649357906 GO:0005178 integrin binding 15/425 161/18639 0.093167701863354 4.08600657654366 4.35487742285702e-06 0.000246218069676916 GO:0005518 collagen binding 10/425 72/18639 0.138888888888889 6.09117647058823 5.18912698682102e-06 0.000256018495067189 GO:1901681 sulfur compound binding 20/425 275/18639 0.0727272727272727 3.1895614973262 5.53643053338052e-06 0.000256018495067189 GO:0003954 NADH dehydrogenase activity 8/425 44/18639 0.181818181818182 7.97390374331551 5.90411186579992e-06 0.000256018495067189 GO:0071813 lipoprotein particle binding 7/425 32/18639 0.21875 9.59360294117647 6.26984069552298e-06 0.000256018495067189 GO:0071814 protein-lipid complex binding 7/425 32/18639 0.21875 9.59360294117647 6.26984069552298e-06 0.000256018495067189 GO:0022853 active monoatomic ion transmembrane transporter activity 12/425 118/18639 0.101694915254237 4.45998005982054 1.63149615424011e-05 0.00063113140703499 GO:0050840 extracellular matrix binding 9/425 67/18639 0.134328358208955 5.89116769095698 2.03083050416432e-05 0.000746330210280386 GO:0030169 low-density lipoprotein particle binding 5/425 17/18639 0.294117647058824 12.8989619377163 2.9704377613866e-05 0.00103965321648531 GO:0016651 oxidoreductase activity, acting on NAD(P)H 10/425 88/18639 0.113636363636364 4.98368983957219 3.15898171869465e-05 0.00105538707420026 GO:0008137 NADH dehydrogenase (ubiquinone) activity 7/425 41/18639 0.170731707317073 7.48769010043042 3.50877925943728e-05 0.00112128380682017 GO:0098631 cell adhesion mediator activity 9/425 76/18639 0.118421052631579 5.19352941176471 5.64833808616582e-05 0.00172980353888828 GO:0019864 IgG binding 4/425 11/18639 0.363636363636364 15.947807486631 7.74543636749032e-05 0.00227715829204215 GO:0015078 proton transmembrane transporter activity 14/425 185/18639 0.0756756756756757 3.3188680445151 9.18225839283124e-05 0.00259575381489652 GO:0038187 pattern recognition receptor activity 7/425 48/18639 0.145833333333333 6.39573529411765 0.000100174968210628 0.00272698524573375 GO:0019825 oxygen binding 6/425 34/18639 0.176470588235294 7.73937716262976 0.000106166559133497 0.00273119606426059 GO:0001540 amyloid-beta binding 9/425 83/18639 0.108433734939759 4.75552090715804 0.000113262057011008 0.00273119606426059 GO:0030021 extracellular matrix structural constituent conferring compression resistance 5/425 22/18639 0.227272727272727 9.96737967914438 0.000115056923465776 0.00273119606426059 GO:0015399 primary active transmembrane transporter activity 13/425 166/18639 0.0783132530120482 3.43454287739192 0.000115193303390583 0.00273119606426059 GO:0016209 antioxidant activity 9/425 86/18639 0.104651162790698 4.58963064295486 0.000149223789005473 0.00342748390371945 GO:0070700 BMP receptor binding 4/425 13/18639 0.307692307692308 13.4942986425339 0.000161839230661014 0.00360460104654077 GO:0043394 proteoglycan binding 6/425 37/18639 0.162162162162162 7.11186009538951 0.00017322384387074 0.0037446919189704 GO:0098632 cell-cell adhesion mediator activity 7/425 55/18639 0.127272727272727 5.58173262032085 0.000240755056437874 0.00505585618519536 GO:0004129 cytochrome-c oxidase activity 4/425 15/18639 0.266666666666667 11.6950588235294 0.000297975216559301 0.00583456520947206 GO:0005041 low-density lipoprotein particle receptor activity 4/425 15/18639 0.266666666666667 11.6950588235294 0.000297975216559301 0.00583456520947206 GO:0004601 peroxidase activity 7/425 57/18639 0.12280701754386 5.38588235294118 0.000301650990421685 0.00583456520947206 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 7/425 58/18639 0.120689655172414 5.29302231237323 0.000336421061414503 0.00634024308050409 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 7/425 59/18639 0.11864406779661 5.20331006979063 0.000374330619945827 0.00687832514150457 GO:0016675 oxidoreductase activity, acting on a heme group of donors 4/425 16/18639 0.25 10.9641176470588 0.000390178000238932 0.00699465439452719 GO:0020037 heme binding 11/425 142/18639 0.0774647887323944 3.39733222866611 0.000418494099853581 0.00732364674743766 GO:0015026 coreceptor activity 7/425 61/18639 0.114754098360656 5.03270973963356 0.000460386511693741 0.00786939735104418 GO:0005543 phospholipid binding 24/425 497/18639 0.0482897384305835 2.11781749319446 0.00048587173217243 0.00811626643515309 GO:0033218 amide binding 15/425 247/18639 0.0607287449392713 2.66334841628959 0.000575700965500448 0.00940311576984066 GO:0070325 lipoprotein particle receptor binding 5/425 31/18639 0.161290322580645 7.07362428842505 0.000627085654143509 0.00989482892704281 GO:0030228 lipoprotein particle receptor activity 4/425 18/18639 0.222222222222222 9.74588235294118 0.000632730557239472 0.00989482892704281 GO:0061134 peptidase regulator activity 14/425 226/18639 0.0619469026548673 2.71677251431546 0.000716453970579494 0.0109707014244985 GO:0046906 tetrapyrrole binding 11/425 152/18639 0.0723684210526316 3.17382352941176 0.000742368081914236 0.0111355212287135 GO:0008083 growth factor activity 11/425 162/18639 0.0679012345679012 2.97790849673203 0.00125174439260782 0.0184006425713349 GO:0005540 hyaluronic acid binding 4/425 24/18639 0.166666666666667 7.30941176470588 0.00197211673769955 0.0278751115809456 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 4/425 24/18639 0.166666666666667 7.30941176470588 0.00197211673769955 0.0278751115809456 GO:0030246 carbohydrate binding 15/425 280/18639 0.0535714285714286 2.3494537815126 0.00202146550297663 0.0280335310318457 GO:0120020 cholesterol transfer activity 4/425 25/18639 0.16 7.01703529411765 0.0023059648474286 0.0313867437566671 GO:0019865 immunoglobulin binding 4/425 26/18639 0.153846153846154 6.74714932126697 0.00267675727763147 0.0345160806852479 GO:0030247 polysaccharide binding 4/425 26/18639 0.153846153846154 6.74714932126697 0.00267675727763147 0.0345160806852479 GO:0050750 low-density lipoprotein particle receptor binding 4/425 26/18639 0.153846153846154 6.74714932126697 0.00267675727763147 0.0345160806852479 GO:0008035 high-density lipoprotein particle binding 3/425 13/18639 0.230769230769231 10.1207239819005 0.00283955986695314 0.0353741780035687 GO:0035325 Toll-like receptor binding 3/425 13/18639 0.230769230769231 10.1207239819005 0.00283955986695314 0.0353741780035687 GO:0140375 immune receptor activity 10/425 156/18639 0.0641025641025641 2.81131221719457 0.00312721703301513 0.0383084086544353 GO:0019763 immunoglobulin receptor activity 3/425 14/18639 0.214285714285714 9.39781512605042 0.00355330155447296 0.0428143711891414 GO:0002020 protease binding 9/425 136/18639 0.0661764705882353 2.90226643598616 0.00401781390010095 0.0476305357511968 GO:0005523 tropomyosin binding 3/425 15/18639 0.2 8.77129411764706 0.00436713313895137 0.0509498866210993 GO:0033612 receptor serine/threonine kinase binding 4/425 30/18639 0.133333333333333 5.84752941176471 0.00456755341959256 0.0524554963031333 GO:0097110 scaffold protein binding 6/425 70/18639 0.0857142857142857 3.75912605042017 0.00520330099791687 0.0588373266687523 GO:0043425 bHLH transcription factor binding 4/425 32/18639 0.125 5.48205882352941 0.00578302374747742 0.0632548253361606 GO:0120015 sterol transfer activity 4/425 32/18639 0.125 5.48205882352941 0.00578302374747742 0.0632548253361606 GO:0035091 phosphatidylinositol binding 14/425 284/18639 0.0492957746478873 2.16193869096935 0.00585214710593051 0.0632548253361606 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 3/425 17/18639 0.176470588235294 7.73937716262976 0.00630999181484487 0.0653217462522673 GO:0015278 intracellularly gated calcium channel activity 3/425 17/18639 0.176470588235294 7.73937716262976 0.00630999181484487 0.0653217462522673 GO:0019198 transmembrane receptor protein phosphatase activity 3/425 17/18639 0.176470588235294 7.73937716262976 0.00630999181484487 0.0653217462522673 GO:0003779 actin binding 19/425 443/18639 0.0428893905191874 1.88097729385208 0.00659060114364853 0.067279053341412 GO:0004857 enzyme inhibitor activity 18/425 416/18639 0.0432692307692308 1.89763574660633 0.00739398373334942 0.0729653518503863 GO:0035615 clathrin adaptor activity 3/425 18/18639 0.166666666666667 7.30941176470588 0.00744544406636595 0.0729653518503863 GO:0098641 cadherin binding involved in cell-cell adhesion 3/425 18/18639 0.166666666666667 7.30941176470588 0.00744544406636595 0.0729653518503863 GO:0016504 peptidase activator activity 5/425 57/18639 0.087719298245614 3.84705882352941 0.00953796908340081 0.092242201003942 GO:1901981 phosphatidylinositol phosphate binding 10/425 185/18639 0.0540540540540541 2.3706200317965 0.0101308788573963 0.0967038436387825 GO:0005179 hormone activity 8/425 132/18639 0.0606060606060606 2.6579679144385 0.0108408913375547 0.102154552988496 GO:0070888 E-box binding 5/425 59/18639 0.0847457627118644 3.71665004985045 0.0109922429458782 0.102269602091399 GO:0001846 opsonin binding 3/425 21/18639 0.142857142857143 6.26521008403361 0.011538430850051 0.104700576231944 GO:0140312 cargo adaptor activity 3/425 21/18639 0.142857142857143 6.26521008403361 0.011538430850051 0.104700576231944 GO:0001530 lipopolysaccharide binding 4/425 41/18639 0.0975609756097561 4.27868005738881 0.0138773498764717 0.124388440965936 GO:0008081 phosphoric diester hydrolase activity 6/425 87/18639 0.0689655172413793 3.02458417849899 0.0145423563831528 0.128778698091775 GO:0005158 insulin receptor binding 3/425 23/18639 0.130434782608696 5.72040920716112 0.0148578033307812 0.130005779144336 GO:0030414 peptidase inhibitor activity 9/425 169/18639 0.0532544378698225 2.33555168813087 0.0156528906817369 0.135351466483254 GO:0048156 tau protein binding 4/425 43/18639 0.0930232558139535 4.07967168262654 0.0163231046634169 0.139505603809435 GO:0019955 cytokine binding 8/425 144/18639 0.0555555555555556 2.43647058823529 0.0175524598352059 0.148288022745705 GO:0022804 active transmembrane transporter activity 18/425 457/18639 0.0393873085339169 1.72738833826747 0.0179236911210503 0.149703556522408 GO:0001848 complement binding 3/425 25/18639 0.12 5.26277647058823 0.0186612499085569 0.1540081658039 GO:0005125 cytokine activity 11/425 234/18639 0.047008547008547 2.06162895927602 0.018858142751498 0.1540081658039 GO:0001664 G protein-coupled receptor binding 13/425 297/18639 0.0437710437710438 1.91964349376114 0.0192606760452074 0.155566998826675 GO:0030276 clathrin binding 4/425 46/18639 0.0869565217391304 3.81360613810742 0.0204702701933048 0.158837969182674 GO:0016175 superoxide-generating NAD(P)H oxidase activity 2/425 10/18639 0.2 8.77129411764706 0.0206788337914455 0.158837969182674 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 2/425 10/18639 0.2 8.77129411764706 0.0206788337914455 0.158837969182674 GO:0008198 ferrous iron binding 3/425 26/18639 0.115384615384615 5.06036199095023 0.020746183729982 0.158837969182674 GO:0030507 spectrin binding 3/425 26/18639 0.115384615384615 5.06036199095023 0.020746183729982 0.158837969182674 GO:0051015 actin filament binding 10/425 209/18639 0.0478468899521531 2.09839572192513 0.0219856652645387 0.16659241205604 GO:0001851 complement component C3b binding 2/425 11/18639 0.181818181818182 7.97390374331551 0.0248975209949907 0.181184930013051 GO:0008046 axon guidance receptor activity 2/425 11/18639 0.181818181818182 7.97390374331551 0.0248975209949907 0.181184930013051 GO:0008199 ferric iron binding 2/425 11/18639 0.181818181818182 7.97390374331551 0.0248975209949907 0.181184930013051 GO:0032050 clathrin heavy chain binding 2/425 11/18639 0.181818181818182 7.97390374331551 0.0248975209949907 0.181184930013051 GO:0061135 endopeptidase regulator activity 9/425 184/18639 0.0489130434782609 2.14515345268542 0.0255625273253942 0.184200564550634 GO:0042826 histone deacetylase binding 7/425 127/18639 0.0551181102362205 2.41728578045391 0.0264578621556321 0.188801249363005 GO:0048029 monosaccharide binding 5/425 74/18639 0.0675675675675676 2.96327503974563 0.0268814072053024 0.189979175922089 GO:0003785 actin monomer binding 3/425 29/18639 0.103448275862069 4.53687626774848 0.0277360098642185 0.19232044575661 GO:0099604 ligand-gated calcium channel activity 3/425 29/18639 0.103448275862069 4.53687626774848 0.0277360098642185 0.19232044575661 GO:0042277 peptide binding 11/425 249/18639 0.0441767068273092 1.93743444365698 0.0281565874781421 0.193412072863873 GO:0005021 vascular endothelial growth factor receptor activity 4/425 51/18639 0.0784313725490196 3.439723183391 0.0287077194728157 0.194892204867236 GO:0004875 complement receptor activity 2/425 12/18639 0.166666666666667 7.30941176470588 0.0294327003268887 0.194892204867236 GO:0016208 AMP binding 2/425 12/18639 0.166666666666667 7.30941176470588 0.0294327003268887 0.194892204867236 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 2/425 12/18639 0.166666666666667 7.30941176470588 0.0294327003268887 0.194892204867236 GO:0001968 fibronectin binding 3/425 30/18639 0.1 4.38564705882353 0.0303102828025104 0.197150954511904 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 3/425 30/18639 0.1 4.38564705882353 0.0303102828025104 0.197150954511904 GO:0004866 endopeptidase inhibitor activity 8/425 161/18639 0.0496894409937888 2.17920350748995 0.0315472787353984 0.203396928688753 GO:0016860 intramolecular oxidoreductase activity 4/425 53/18639 0.0754716981132075 3.30992230854606 0.0324791768485432 0.207584304205906 GO:0017147 Wnt-protein binding 3/425 31/18639 0.0967741935483871 4.24417457305503 0.0330058852718635 0.209132117886376 GO:0046332 SMAD binding 5/425 79/18639 0.0632911392405063 2.77572598659717 0.0343435694905791 0.214564758582808 GO:0008013 beta-catenin binding 6/425 106/18639 0.0566037735849057 2.48244173140955 0.034447131309893 0.214564758582808 GO:0048306 calcium-dependent protein binding 5/425 80/18639 0.0625 2.74102941176471 0.0359750133361563 0.222198611782142 GO:0044325 transmembrane transporter binding 7/425 136/18639 0.0514705882352941 2.25731833910035 0.0364382143709006 0.223184063021766 GO:0001618 virus receptor activity 5/425 81/18639 0.0617283950617284 2.70718954248366 0.0376534590279855 0.228721424674127 GO:0140272 exogenous protein binding 5/425 82/18639 0.0609756097560976 2.67417503586801 0.039379137234906 0.229756932090559 GO:0005161 platelet-derived growth factor receptor binding 2/425 14/18639 0.142857142857143 6.26521008403361 0.0393869026440958 0.229756932090559 GO:0005545 1-phosphatidylinositol binding 2/425 14/18639 0.142857142857143 6.26521008403361 0.0393869026440958 0.229756932090559 GO:0034236 protein kinase A catalytic subunit binding 2/425 14/18639 0.142857142857143 6.26521008403361 0.0393869026440958 0.229756932090559 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 2/425 14/18639 0.142857142857143 6.26521008403361 0.0393869026440958 0.229756932090559 GO:0070851 growth factor receptor binding 7/425 139/18639 0.0503597122302158 2.20859923825645 0.0402501673477047 0.232943881894197 GO:0001786 phosphatidylserine binding 4/425 59/18639 0.0677966101694915 2.97332003988036 0.045456072928064 0.261017293766618 GO:0004714 transmembrane receptor protein tyrosine kinase activity 4/425 60/18639 0.0666666666666667 2.92376470588235 0.047861995919939 0.271017526858969 GO:0017124 SH3 domain binding 6/425 115/18639 0.0521739130434783 2.28816368286445 0.0480881757025358 0.271017526858969 GO:0005516 calmodulin binding 9/425 207/18639 0.0434782608695652 1.90680306905371 0.0483038041068367 0.271017526858969 GO:0005159 insulin-like growth factor receptor binding 2/425 16/18639 0.125 5.48205882352941 0.0504159405587447 0.276535196348338 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/425 16/18639 0.125 5.48205882352941 0.0504159405587447 0.276535196348338 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 2/425 16/18639 0.125 5.48205882352941 0.0504159405587447 0.276535196348338 GO:0005126 cytokine receptor binding 11/425 275/18639 0.04 1.75425882352941 0.0513895746500601 0.279262799280834 GO:0042805 actinin binding 3/425 37/18639 0.0810810810810811 3.55593004769475 0.0516731166016237 0.279262799280834 GO:0005109 frizzled binding 3/425 38/18639 0.0789473684210526 3.46235294117647 0.0551878457859404 0.296080778486614 GO:0008429 phosphatidylethanolamine binding 2/425 17/18639 0.117647058823529 5.15958477508651 0.056296733724598 0.299567580071398 GO:0030695 GTPase regulator activity 17/425 489/18639 0.0347648261758691 1.52466257668712 0.0569531349971638 0.299567580071398 GO:0072341 modified amino acid binding 5/425 91/18639 0.0549450549450549 2.40969618616677 0.0570604914421711 0.299567580071398 GO:0060589 nucleoside-triphosphatase regulator activity 17/425 490/18639 0.0346938775510204 1.52155102040816 0.0578207563880132 0.30140607053326 GO:0043178 alcohol binding 5/425 92/18639 0.0543478260869565 2.38350383631714 0.0592653064253392 0.306760564948058 GO:0120013 lipid transfer activity 4/425 65/18639 0.0615384615384615 2.69885972850679 0.0609253243253784 0.312743866435683 GO:0008525 phosphatidylcholine transporter activity 2/425 18/18639 0.111111111111111 4.87294117647059 0.062403144931877 0.312743866435683 GO:0034185 apolipoprotein binding 2/425 18/18639 0.111111111111111 4.87294117647059 0.062403144931877 0.312743866435683 GO:0070064 proline-rich region binding 2/425 18/18639 0.111111111111111 4.87294117647059 0.062403144931877 0.312743866435683 GO:0071855 neuropeptide receptor binding 3/425 40/18639 0.075 3.28923529411765 0.0625487732871365 0.312743866435683 GO:0005506 iron ion binding 7/425 154/18639 0.0454545454545455 1.99347593582888 0.0631497588472221 0.313615356437218 GO:0004867 serine-type endopeptidase inhibitor activity 5/425 95/18639 0.0526315789473684 2.30823529411765 0.0661675269944153 0.325317145005305 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 3/425 41/18639 0.0731707317073171 3.20901004304161 0.0663912540827153 0.325317145005305 GO:0030506 ankyrin binding 2/425 19/18639 0.105263157894737 4.61647058823529 0.0687218820967514 0.330134531641257 GO:0043395 heparan sulfate proteoglycan binding 2/425 19/18639 0.105263157894737 4.61647058823529 0.0687218820967514 0.330134531641257 GO:0046624 sphingolipid transporter activity 2/425 19/18639 0.105263157894737 4.61647058823529 0.0687218820967514 0.330134531641257 GO:0042056 chemoattractant activity 3/425 42/18639 0.0714285714285714 3.13260504201681 0.070339125743244 0.333543596266351 GO:0048487 beta-tubulin binding 3/425 42/18639 0.0714285714285714 3.13260504201681 0.070339125743244 0.333543596266351 GO:0016004 phospholipase activator activity 2/425 20/18639 0.1 4.38564705882353 0.0752401394770927 0.354496810997841 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/425 21/18639 0.0952380952380952 4.17680672268908 0.0819455824904655 0.381202551458811 GO:0072542 protein phosphatase activator activity 2/425 21/18639 0.0952380952380952 4.17680672268908 0.0819455824904655 0.381202551458811 GO:0008009 chemokine activity 3/425 45/18639 0.0666666666666667 2.92376470588235 0.0827941425028263 0.382727639871555 GO:0043539 protein serine/threonine kinase activator activity 4/425 73/18639 0.0547945205479452 2.40309427880741 0.0853158289149929 0.391919589078249 GO:0016829 lyase activity 8/425 200/18639 0.04 1.75425882352941 0.0881200095767643 0.40228700024175 GO:0008093 cytoskeletal anchor activity 2/425 22/18639 0.0909090909090909 3.98695187165775 0.0888263329690203 0.403008362544629 GO:0005096 GTPase activator activity 10/425 271/18639 0.03690036900369 1.61831994790536 0.0928245719745429 0.418564787737969 GO:0140297 DNA-binding transcription factor binding 16/425 488/18639 0.0327868852459016 1.43791706846673 0.0941953800828046 0.418974414019118 GO:0031681 G-protein beta-subunit binding 2/425 23/18639 0.0869565217391304 3.81360613810742 0.0958709548393288 0.418974414019118 GO:0005004 GPI-linked ephrin receptor activity 3/425 49/18639 0.0612244897959184 2.68509003601441 0.100744272456518 0.418974414019118 GO:0005008 hepatocyte growth factor receptor activity 3/425 49/18639 0.0612244897959184 2.68509003601441 0.100744272456518 0.418974414019118 GO:0005009 insulin receptor activity 3/425 49/18639 0.0612244897959184 2.68509003601441 0.100744272456518 0.418974414019118 GO:0005011 macrophage colony-stimulating factor receptor activity 3/425 49/18639 0.0612244897959184 2.68509003601441 0.100744272456518 0.418974414019118 GO:0005018 platelet-derived growth factor alpha-receptor activity 3/425 49/18639 0.0612244897959184 2.68509003601441 0.100744272456518 0.418974414019118 GO:0005020 stem cell factor receptor activity 3/425 49/18639 0.0612244897959184 2.68509003601441 0.100744272456518 0.418974414019118 GO:0008288 boss receptor activity 3/425 49/18639 0.0612244897959184 2.68509003601441 0.100744272456518 0.418974414019118 GO:0036332 placental growth factor receptor activity 3/425 49/18639 0.0612244897959184 2.68509003601441 0.100744272456518 0.418974414019118 GO:0038062 protein tyrosine kinase collagen receptor activity 3/425 49/18639 0.0612244897959184 2.68509003601441 0.100744272456518 0.418974414019118 GO:0060175 brain-derived neurotrophic factor receptor activity 3/425 49/18639 0.0612244897959184 2.68509003601441 0.100744272456518 0.418974414019118 GO:0004713 protein tyrosine kinase activity 6/425 140/18639 0.0428571428571429 1.87956302521008 0.101370180625154 0.418974414019118 GO:0019199 transmembrane receptor protein kinase activity 4/425 78/18639 0.0512820512820513 2.24904977375566 0.102624931920102 0.418974414019118 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 2/425 24/18639 0.0833333333333333 3.65470588235294 0.10306844021552 0.418974414019118 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 2/425 24/18639 0.0833333333333333 3.65470588235294 0.10306844021552 0.418974414019118 GO:0060229 lipase activator activity 2/425 24/18639 0.0833333333333333 3.65470588235294 0.10306844021552 0.418974414019118 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 12/425 349/18639 0.0343839541547278 1.50795887409405 0.104357383293718 0.418974414019118 GO:0005006 epidermal growth factor receptor activity 3/425 50/18639 0.06 2.63138823529412 0.10545614502522 0.418974414019118 GO:0005007 fibroblast growth factor receptor activity 3/425 50/18639 0.06 2.63138823529412 0.10545614502522 0.418974414019118 GO:0005017 platelet-derived growth factor receptor activity 3/425 50/18639 0.06 2.63138823529412 0.10545614502522 0.418974414019118 GO:0005019 platelet-derived growth factor beta-receptor activity 3/425 50/18639 0.06 2.63138823529412 0.10545614502522 0.418974414019118 GO:0003735 structural constituent of ribosome 7/425 175/18639 0.04 1.75425882352941 0.106263264629573 0.419911287649117 GO:1902936 phosphatidylinositol bisphosphate binding 5/425 111/18639 0.045045045045045 1.97551669316375 0.110076625923508 0.422656374908199 GO:0005010 insulin-like growth factor receptor activity 3/425 51/18639 0.0588235294117647 2.57979238754325 0.110252921622245 0.422656374908199 GO:0005030 neurotrophin receptor activity 3/425 51/18639 0.0588235294117647 2.57979238754325 0.110252921622245 0.422656374908199 GO:0016830 carbon-carbon lyase activity 3/425 51/18639 0.0588235294117647 2.57979238754325 0.110252921622245 0.422656374908199 GO:0005537 D-mannose binding 2/425 25/18639 0.08 3.50851764705882 0.110408195894387 0.422656374908199 GO:0019211 phosphatase activator activity 2/425 25/18639 0.08 3.50851764705882 0.110408195894387 0.422656374908199 GO:0005200 structural constituent of cytoskeleton 5/425 112/18639 0.0446428571428571 1.9578781512605 0.113200716290592 0.431101173438264 GO:0004112 cyclic-nucleotide phosphodiesterase activity 2/425 26/18639 0.0769230769230769 3.37357466063348 0.11788003024142 0.44133559192396 GO:0008143 poly(A) binding 2/425 26/18639 0.0769230769230769 3.37357466063348 0.11788003024142 0.44133559192396 GO:0034237 protein kinase A regulatory subunit binding 2/425 26/18639 0.0769230769230769 3.37357466063348 0.11788003024142 0.44133559192396 GO:0005003 ephrin receptor activity 3/425 53/18639 0.0566037735849057 2.48244173140955 0.120091317530329 0.44133559192396 GO:0005005 transmembrane-ephrin receptor activity 3/425 53/18639 0.0566037735849057 2.48244173140955 0.120091317530329 0.44133559192396 GO:0017046 peptide hormone binding 3/425 53/18639 0.0566037735849057 2.48244173140955 0.120091317530329 0.44133559192396 GO:0038064 collagen receptor activity 3/425 53/18639 0.0566037735849057 2.48244173140955 0.120091317530329 0.44133559192396 GO:0015485 cholesterol binding 3/425 54/18639 0.0555555555555556 2.43647058823529 0.125127957769801 0.452075947234947 GO:0004364 glutathione transferase activity 2/425 27/18639 0.0740740740740741 3.24862745098039 0.125474140457046 0.452075947234947 GO:0005104 fibroblast growth factor receptor binding 2/425 27/18639 0.0740740740740741 3.24862745098039 0.125474140457046 0.452075947234947 GO:0008266 poly(U) RNA binding 2/425 27/18639 0.0740740740740741 3.24862745098039 0.125474140457046 0.452075947234947 GO:0042578 phosphoric ester hydrolase activity 12/425 363/18639 0.0330578512396694 1.44980068060282 0.128295187416397 0.459985184151471 GO:1990782 protein tyrosine kinase binding 5/425 117/18639 0.0427350427350427 1.87420814479638 0.12944520093201 0.461855449927318 GO:0140313 molecular sequestering activity 3/425 55/18639 0.0545454545454545 2.39217112299465 0.130239551921572 0.462444785808479 GO:0051393 alpha-actinin binding 2/425 28/18639 0.0714285714285714 3.13260504201681 0.13318110021259 0.468870061355159 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 4/425 86/18639 0.0465116279069767 2.03983584131327 0.133324956222079 0.468870061355159 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 2/425 29/18639 0.0689655172413793 3.02458417849899 0.140991847645802 0.493004646093083 GO:0004197 cysteine-type endopeptidase activity 4/425 88/18639 0.0454545454545455 1.99347593582888 0.141529224932844 0.493004646093083 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 4/425 89/18639 0.0449438202247191 1.97107732980833 0.14570494718037 0.50278467689001 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 4/425 89/18639 0.0449438202247191 1.97107732980833 0.14570494718037 0.50278467689001 GO:0008187 poly-pyrimidine tract binding 2/425 30/18639 0.0666666666666667 2.92376470588235 0.148897673706038 0.505492064123027 GO:0031210 phosphatidylcholine binding 2/425 30/18639 0.0666666666666667 2.92376470588235 0.148897673706038 0.505492064123027 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/425 30/18639 0.0666666666666667 2.92376470588235 0.148897673706038 0.505492064123027 GO:0019210 kinase inhibitor activity 4/425 90/18639 0.0444444444444444 1.94917647058824 0.149928258474585 0.505492064123027 GO:0140793 histone H2AXY142 phosphatase activity 4/425 90/18639 0.0444444444444444 1.94917647058824 0.149928258474585 0.505492064123027 GO:0001216 DNA-binding transcription activator activity 15/425 491/18639 0.0305498981670061 1.33981071043489 0.155174053059062 0.52078963012973 GO:0005085 guanyl-nucleotide exchange factor activity 8/425 230/18639 0.0347826086956522 1.52544245524297 0.156517777004192 0.521784185370952 GO:0005184 neuropeptide hormone activity 2/425 31/18639 0.0645161290322581 2.82944971537002 0.156890210839429 0.521784185370952 GO:0070717 poly-purine tract binding 2/425 32/18639 0.0625 2.74102941176471 0.164961422004685 0.543706929028893 GO:0160041 neuropeptide activity 2/425 32/18639 0.0625 2.74102941176471 0.164961422004685 0.543706929028893 GO:0042562 hormone binding 4/425 94/18639 0.0425531914893617 1.86623279098874 0.167274873101901 0.548870677365612 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2/425 33/18639 0.0606060606060606 2.6579679144385 0.173103590010358 0.558031309901811 GO:0019956 chemokine binding 2/425 33/18639 0.0606060606060606 2.6579679144385 0.173103590010358 0.558031309901811 GO:0030296 protein tyrosine kinase activator activity 2/425 33/18639 0.0606060606060606 2.6579679144385 0.173103590010358 0.558031309901811 GO:0140311 protein sequestering activity 2/425 33/18639 0.0606060606060606 2.6579679144385 0.173103590010358 0.558031309901811 GO:0016798 hydrolase activity, acting on glycosyl bonds 5/425 130/18639 0.0384615384615385 1.68678733031674 0.176140057600852 0.563087224870096 GO:0004896 cytokine receptor activity 4/425 96/18639 0.0416666666666667 1.82735294117647 0.176204165605608 0.563087224870096 GO:0008376 acetylgalactosaminyltransferase activity 2/425 34/18639 0.0588235294117647 2.57979238754325 0.181309307164697 0.574406641232983 GO:0015020 glucuronosyltransferase activity 2/425 34/18639 0.0588235294117647 2.57979238754325 0.181309307164697 0.574406641232983 GO:0004725 protein tyrosine phosphatase activity 4/425 98/18639 0.0408163265306122 1.7900600240096 0.185291714811211 0.582006027291623 GO:0008170 N-methyltransferase activity 4/425 98/18639 0.0408163265306122 1.7900600240096 0.185291714811211 0.582006027291623 GO:0016500 protein-hormone receptor activity 3/425 67/18639 0.0447761194029851 1.96372256365233 0.196511024494412 0.5885135353981 GO:0032934 sterol binding 3/425 68/18639 0.0441176470588235 1.93484429065744 0.202369454829024 0.5885135353981 GO:1990841 promoter-specific chromatin binding 3/425 68/18639 0.0441176470588235 1.93484429065744 0.202369454829024 0.5885135353981 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.5885135353981 GO:0003796 lysozyme activity 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.5885135353981 GO:0004955 prostaglandin receptor activity 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.5885135353981 GO:0005131 growth hormone receptor binding 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.5885135353981 GO:0005381 iron ion transmembrane transporter activity 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.5885135353981 GO:0008239 dipeptidyl-peptidase activity 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.5885135353981 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.5885135353981 GO:0030957 Tat protein binding 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.5885135353981 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.5885135353981 GO:0032052 bile acid binding 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.5885135353981 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.5885135353981 GO:0043121 neurotrophin binding 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.5885135353981 GO:0047429 nucleoside triphosphate diphosphatase activity 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.5885135353981 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.5885135353981 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.5885135353981 GO:1905394 retromer complex binding 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.5885135353981 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/425 10/18639 0.1 4.38564705882353 0.206032427930228 0.5885135353981 GO:0022829 wide pore channel activity 2/425 37/18639 0.0540540540540541 2.3706200317965 0.206238110187106 0.5885135353981 GO:0019207 kinase regulator activity 9/425 287/18639 0.0313588850174216 1.3752900184464 0.210269116005876 0.5885135353981 GO:0030295 protein kinase activator activity 5/425 139/18639 0.0359712230215827 1.5775708844689 0.211683578914666 0.5885135353981 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 14/425 484/18639 0.0289256198347107 1.26857559552747 0.217462555083312 0.5885135353981 GO:0005319 lipid transporter activity 6/425 178/18639 0.0337078651685393 1.47830799735625 0.22163025410802 0.5885135353981 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 2/425 39/18639 0.0512820512820513 2.24904977375566 0.223052284637306 0.5885135353981 GO:0003953 NAD+ nucleosidase activity 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.5885135353981 GO:0004954 prostanoid receptor activity 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.5885135353981 GO:0005536 D-glucose binding 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.5885135353981 GO:0008172 S-methyltransferase activity 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.5885135353981 GO:0008526 phosphatidylinositol transfer activity 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.5885135353981 GO:0015173 aromatic amino acid transmembrane transporter activity 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.5885135353981 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.5885135353981 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.5885135353981 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.5885135353981 GO:0034713 type I transforming growth factor beta receptor binding 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.5885135353981 GO:0035252 UDP-xylosyltransferase activity 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.5885135353981 GO:0042285 xylosyltransferase activity 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.5885135353981 GO:0050786 RAGE receptor binding 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.5885135353981 GO:0050998 nitric-oxide synthase binding 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.5885135353981 GO:0097493 structural molecule activity conferring elasticity 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.5885135353981 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.5885135353981 GO:0140031 phosphorylation-dependent protein binding 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.5885135353981 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.5885135353981 GO:1990948 ubiquitin ligase inhibitor activity 1/425 11/18639 0.0909090909090909 3.98695187165775 0.224145918623752 0.5885135353981 GO:0042379 chemokine receptor binding 3/425 72/18639 0.0416666666666667 1.82735294117647 0.226183643426726 0.5885135353981 GO:0019887 protein kinase regulator activity 8/425 255/18639 0.0313725490196078 1.3758892733564 0.227935281607485 0.5885135353981 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 2/425 40/18639 0.05 2.19282352941176 0.231499837866262 0.5885135353981 GO:0050997 quaternary ammonium group binding 2/425 40/18639 0.05 2.19282352941176 0.231499837866262 0.5885135353981 GO:0005496 steroid binding 4/425 108/18639 0.037037037037037 1.6243137254902 0.232772925582522 0.5885135353981 GO:0008227 G protein-coupled amine receptor activity 2/425 41/18639 0.0487804878048781 2.1393400286944 0.239966944726957 0.5885135353981 GO:0017080 sodium channel regulator activity 2/425 41/18639 0.0487804878048781 2.1393400286944 0.239966944726957 0.5885135353981 GO:0042287 MHC protein binding 2/425 41/18639 0.0487804878048781 2.1393400286944 0.239966944726957 0.5885135353981 GO:0140828 metal cation:monoatomic cation antiporter activity 2/425 41/18639 0.0487804878048781 2.1393400286944 0.239966944726957 0.5885135353981 GO:0000340 RNA 7-methylguanosine cap binding 1/425 12/18639 0.0833333333333333 3.65470588235294 0.241847120287103 0.5885135353981 GO:0004859 phospholipase inhibitor activity 1/425 12/18639 0.0833333333333333 3.65470588235294 0.241847120287103 0.5885135353981 GO:0005095 GTPase inhibitor activity 1/425 12/18639 0.0833333333333333 3.65470588235294 0.241847120287103 0.5885135353981 GO:0005247 voltage-gated chloride channel activity 1/425 12/18639 0.0833333333333333 3.65470588235294 0.241847120287103 0.5885135353981 GO:0015132 prostaglandin transmembrane transporter activity 1/425 12/18639 0.0833333333333333 3.65470588235294 0.241847120287103 0.5885135353981 GO:0015368 calcium:monoatomic cation antiporter activity 1/425 12/18639 0.0833333333333333 3.65470588235294 0.241847120287103 0.5885135353981 GO:0034452 dynactin binding 1/425 12/18639 0.0833333333333333 3.65470588235294 0.241847120287103 0.5885135353981 GO:0035497 cAMP response element binding 1/425 12/18639 0.0833333333333333 3.65470588235294 0.241847120287103 0.5885135353981 GO:0045295 gamma-catenin binding 1/425 12/18639 0.0833333333333333 3.65470588235294 0.241847120287103 0.5885135353981 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/425 12/18639 0.0833333333333333 3.65470588235294 0.241847120287103 0.5885135353981 GO:0070008 serine-type exopeptidase activity 1/425 12/18639 0.0833333333333333 3.65470588235294 0.241847120287103 0.5885135353981 GO:0070679 inositol 1,4,5 trisphosphate binding 1/425 12/18639 0.0833333333333333 3.65470588235294 0.241847120287103 0.5885135353981 GO:0097677 STAT family protein binding 1/425 12/18639 0.0833333333333333 3.65470588235294 0.241847120287103 0.5885135353981 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/425 12/18639 0.0833333333333333 3.65470588235294 0.241847120287103 0.5885135353981 GO:0004222 metalloendopeptidase activity 4/425 110/18639 0.0363636363636364 1.5947807486631 0.242611702347788 0.5885135353981 GO:0008307 structural constituent of muscle 2/425 42/18639 0.0476190476190476 2.08840336134454 0.248448335676142 0.598719759744146 GO:0019894 kinesin binding 2/425 42/18639 0.0476190476190476 2.08840336134454 0.248448335676142 0.598719759744146 GO:0019209 kinase activator activity 5/425 148/18639 0.0337837837837838 1.48163751987281 0.249282566845592 0.598766949776177 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/425 13/18639 0.0769230769230769 3.37357466063348 0.259145395579849 0.598968131293048 GO:0005172 vascular endothelial growth factor receptor binding 1/425 13/18639 0.0769230769230769 3.37357466063348 0.259145395579849 0.598968131293048 GO:0005542 folic acid binding 1/425 13/18639 0.0769230769230769 3.37357466063348 0.259145395579849 0.598968131293048 GO:0017154 semaphorin receptor activity 1/425 13/18639 0.0769230769230769 3.37357466063348 0.259145395579849 0.598968131293048 GO:0031994 insulin-like growth factor I binding 1/425 13/18639 0.0769230769230769 3.37357466063348 0.259145395579849 0.598968131293048 GO:0032396 inhibitory MHC class I receptor activity 1/425 13/18639 0.0769230769230769 3.37357466063348 0.259145395579849 0.598968131293048 GO:0035673 oligopeptide transmembrane transporter activity 1/425 13/18639 0.0769230769230769 3.37357466063348 0.259145395579849 0.598968131293048 GO:0039706 co-receptor binding 1/425 13/18639 0.0769230769230769 3.37357466063348 0.259145395579849 0.598968131293048 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/425 13/18639 0.0769230769230769 3.37357466063348 0.259145395579849 0.598968131293048 GO:0071714 icosanoid transmembrane transporter activity 1/425 13/18639 0.0769230769230769 3.37357466063348 0.259145395579849 0.598968131293048 GO:0071837 HMG box domain binding 1/425 13/18639 0.0769230769230769 3.37357466063348 0.259145395579849 0.598968131293048 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/425 13/18639 0.0769230769230769 3.37357466063348 0.259145395579849 0.598968131293048 GO:0043177 organic acid binding 6/425 189/18639 0.0317460317460317 1.39226890756303 0.262965113512894 0.602067278491951 GO:0030547 signaling receptor inhibitor activity 2/425 44/18639 0.0454545454545455 1.99347593582888 0.26543402929924 0.602067278491951 GO:0043014 alpha-tubulin binding 2/425 44/18639 0.0454545454545455 1.99347593582888 0.26543402929924 0.602067278491951 GO:0019902 phosphatase binding 6/425 190/18639 0.0315789473684211 1.38494117647059 0.266821485602964 0.602067278491951 GO:0035401 histone H3Y41 kinase activity 4/425 115/18639 0.0347826086956522 1.52544245524297 0.267592365515758 0.602067278491951 GO:0140801 histone H2AXY142 kinase activity 4/425 115/18639 0.0347826086956522 1.52544245524297 0.267592365515758 0.602067278491951 GO:0033293 monocarboxylic acid binding 3/425 79/18639 0.0379746835443038 1.6654355919583 0.268976997890766 0.602067278491951 GO:0004715 non-membrane spanning protein tyrosine kinase activity 2/425 45/18639 0.0444444444444444 1.94917647058824 0.273928907754887 0.602067278491951 GO:0008191 metalloendopeptidase inhibitor activity 1/425 14/18639 0.0714285714285714 3.13260504201681 0.276049895036446 0.602067278491951 GO:0008195 phosphatidate phosphatase activity 1/425 14/18639 0.0714285714285714 3.13260504201681 0.276049895036446 0.602067278491951 GO:0015386 potassium:proton antiporter activity 1/425 14/18639 0.0714285714285714 3.13260504201681 0.276049895036446 0.602067278491951 GO:0015926 glucosidase activity 1/425 14/18639 0.0714285714285714 3.13260504201681 0.276049895036446 0.602067278491951 GO:0019992 diacylglycerol binding 1/425 14/18639 0.0714285714285714 3.13260504201681 0.276049895036446 0.602067278491951 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/425 14/18639 0.0714285714285714 3.13260504201681 0.276049895036446 0.602067278491951 GO:0031404 chloride ion binding 1/425 14/18639 0.0714285714285714 3.13260504201681 0.276049895036446 0.602067278491951 GO:0042043 neurexin family protein binding 1/425 14/18639 0.0714285714285714 3.13260504201681 0.276049895036446 0.602067278491951 GO:0042813 Wnt receptor activity 1/425 14/18639 0.0714285714285714 3.13260504201681 0.276049895036446 0.602067278491951 GO:0044548 S100 protein binding 1/425 14/18639 0.0714285714285714 3.13260504201681 0.276049895036446 0.602067278491951 GO:0061783 peptidoglycan muralytic activity 1/425 14/18639 0.0714285714285714 3.13260504201681 0.276049895036446 0.602067278491951 GO:0019208 phosphatase regulator activity 4/425 117/18639 0.0341880341880342 1.4993665158371 0.277714160473856 0.603905053101432 GO:0004180 carboxypeptidase activity 2/425 46/18639 0.0434782608695652 1.90680306905371 0.282419207214623 0.605742613994144 GO:0030291 protein serine/threonine kinase inhibitor activity 2/425 46/18639 0.0434782608695652 1.90680306905371 0.282419207214623 0.605742613994144 GO:0005504 fatty acid binding 2/425 47/18639 0.0425531914893617 1.86623279098874 0.290900729047136 0.605742613994144 GO:0004089 carbonate dehydratase activity 1/425 15/18639 0.0666666666666667 2.92376470588235 0.292569561861117 0.605742613994144 GO:0004559 alpha-mannosidase activity 1/425 15/18639 0.0666666666666667 2.92376470588235 0.292569561861117 0.605742613994144 GO:0004953 icosanoid receptor activity 1/425 15/18639 0.0666666666666667 2.92376470588235 0.292569561861117 0.605742613994144 GO:0016846 carbon-sulfur lyase activity 1/425 15/18639 0.0666666666666667 2.92376470588235 0.292569561861117 0.605742613994144 GO:0030553 cGMP binding 1/425 15/18639 0.0666666666666667 2.92376470588235 0.292569561861117 0.605742613994144 GO:0031005 filamin binding 1/425 15/18639 0.0666666666666667 2.92376470588235 0.292569561861117 0.605742613994144 GO:0031386 protein tag activity 1/425 15/18639 0.0666666666666667 2.92376470588235 0.292569561861117 0.605742613994144 GO:0045504 dynein heavy chain binding 1/425 15/18639 0.0666666666666667 2.92376470588235 0.292569561861117 0.605742613994144 GO:0051371 muscle alpha-actinin binding 1/425 15/18639 0.0666666666666667 2.92376470588235 0.292569561861117 0.605742613994144 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/425 15/18639 0.0666666666666667 2.92376470588235 0.292569561861117 0.605742613994144 GO:0120283 protein serine/threonine kinase binding 1/425 15/18639 0.0666666666666667 2.92376470588235 0.292569561861117 0.605742613994144 GO:0141047 molecular tag activity 1/425 15/18639 0.0666666666666667 2.92376470588235 0.292569561861117 0.605742613994144 GO:0141050 histone H3K deacetylase activity 1/425 15/18639 0.0666666666666667 2.92376470588235 0.292569561861117 0.605742613994144 GO:0141051 histone H4K deacetylase activity 1/425 15/18639 0.0666666666666667 2.92376470588235 0.292569561861117 0.605742613994144 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/425 48/18639 0.0416666666666667 1.82735294117647 0.299369467586178 0.614916410329911 GO:0032266 phosphatidylinositol-3-phosphate binding 2/425 48/18639 0.0416666666666667 1.82735294117647 0.299369467586178 0.614916410329911 GO:0004860 protein kinase inhibitor activity 3/425 84/18639 0.0357142857142857 1.5663025210084 0.300077589402646 0.614916410329911 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/425 122/18639 0.0327868852459016 1.43791706846673 0.303264659480935 0.614916410329911 GO:0016763 pentosyltransferase activity 2/425 49/18639 0.0408163265306122 1.7900600240096 0.307821603549142 0.614916410329911 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/425 16/18639 0.0625 2.74102941176471 0.308713136614608 0.614916410329911 GO:0015385 sodium:proton antiporter activity 1/425 16/18639 0.0625 2.74102941176471 0.308713136614608 0.614916410329911 GO:0015562 efflux transmembrane transporter activity 1/425 16/18639 0.0625 2.74102941176471 0.308713136614608 0.614916410329911 GO:0015923 mannosidase activity 1/425 16/18639 0.0625 2.74102941176471 0.308713136614608 0.614916410329911 GO:0016722 oxidoreductase activity, acting on metal ions 1/425 16/18639 0.0625 2.74102941176471 0.308713136614608 0.614916410329911 GO:0030275 LRR domain binding 1/425 16/18639 0.0625 2.74102941176471 0.308713136614608 0.614916410329911 GO:0055102 lipase inhibitor activity 1/425 16/18639 0.0625 2.74102941176471 0.308713136614608 0.614916410329911 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/425 16/18639 0.0625 2.74102941176471 0.308713136614608 0.614916410329911 GO:0140328 floppase activity 1/425 16/18639 0.0625 2.74102941176471 0.308713136614608 0.614916410329911 GO:0048020 CCR chemokine receptor binding 2/425 50/18639 0.04 1.75425882352941 0.316253497654305 0.628233299394363 GO:0004175 endopeptidase activity 11/425 405/18639 0.0271604938271605 1.19116339869281 0.320019347971299 0.629286369180731 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/425 17/18639 0.0588235294117647 2.57979238754325 0.324489161795234 0.629286369180731 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/425 17/18639 0.0588235294117647 2.57979238754325 0.324489161795234 0.629286369180731 GO:0030548 acetylcholine receptor regulator activity 1/425 17/18639 0.0588235294117647 2.57979238754325 0.324489161795234 0.629286369180731 GO:0036041 long-chain fatty acid binding 1/425 17/18639 0.0588235294117647 2.57979238754325 0.324489161795234 0.629286369180731 GO:0045125 bioactive lipid receptor activity 1/425 17/18639 0.0588235294117647 2.57979238754325 0.324489161795234 0.629286369180731 GO:0046965 nuclear retinoid X receptor binding 1/425 17/18639 0.0588235294117647 2.57979238754325 0.324489161795234 0.629286369180731 GO:0048038 quinone binding 1/425 17/18639 0.0588235294117647 2.57979238754325 0.324489161795234 0.629286369180731 GO:0070403 NAD+ binding 1/425 17/18639 0.0588235294117647 2.57979238754325 0.324489161795234 0.629286369180731 GO:0005080 protein kinase C binding 2/425 52/18639 0.0384615384615385 1.68678733031674 0.333042866218134 0.635251954170156 GO:0046982 protein heterodimerization activity 10/425 369/18639 0.02710027100271 1.18852223816356 0.334176009070266 0.635251954170156 GO:0004970 glutamate-gated receptor activity 1/425 18/18639 0.0555555555555556 2.43647058823529 0.339905986316608 0.635251954170156 GO:0008308 voltage-gated monoatomic anion channel activity 1/425 18/18639 0.0555555555555556 2.43647058823529 0.339905986316608 0.635251954170156 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/425 18/18639 0.0555555555555556 2.43647058823529 0.339905986316608 0.635251954170156 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/425 18/18639 0.0555555555555556 2.43647058823529 0.339905986316608 0.635251954170156 GO:0017075 syntaxin-1 binding 1/425 18/18639 0.0555555555555556 2.43647058823529 0.339905986316608 0.635251954170156 GO:0032393 MHC class I receptor activity 1/425 18/18639 0.0555555555555556 2.43647058823529 0.339905986316608 0.635251954170156 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 1/425 18/18639 0.0555555555555556 2.43647058823529 0.339905986316608 0.635251954170156 GO:0050811 GABA receptor binding 1/425 18/18639 0.0555555555555556 2.43647058823529 0.339905986316608 0.635251954170156 GO:0099602 neurotransmitter receptor regulator activity 1/425 18/18639 0.0555555555555556 2.43647058823529 0.339905986316608 0.635251954170156 GO:1901611 phosphatidylglycerol binding 1/425 18/18639 0.0555555555555556 2.43647058823529 0.339905986316608 0.635251954170156 GO:1990381 ubiquitin-specific protease binding 1/425 18/18639 0.0555555555555556 2.43647058823529 0.339905986316608 0.635251954170156 GO:0140104 molecular carrier activity 7/425 249/18639 0.0281124497991968 1.23291282778172 0.341087481898706 0.635251954170156 GO:0005544 calcium-dependent phospholipid binding 2/425 53/18639 0.0377358490566038 1.65496115427303 0.341393907343145 0.635251954170156 GO:0051018 protein kinase A binding 2/425 53/18639 0.0377358490566038 1.65496115427303 0.341393907343145 0.635251954170156 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 3/425 91/18639 0.032967032967033 1.44581771170006 0.343859001489639 0.637908120027102 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/425 54/18639 0.037037037037037 1.6243137254902 0.349711828480582 0.637908120027102 GO:0051287 NAD binding 2/425 54/18639 0.037037037037037 1.6243137254902 0.349711828480582 0.637908120027102 GO:0003756 protein disulfide isomerase activity 1/425 19/18639 0.0526315789473684 2.30823529411765 0.354971769884378 0.637908120027102 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/425 19/18639 0.0526315789473684 2.30823529411765 0.354971769884378 0.637908120027102 GO:0005520 insulin-like growth factor binding 1/425 19/18639 0.0526315789473684 2.30823529411765 0.354971769884378 0.637908120027102 GO:0015245 fatty acid transmembrane transporter activity 1/425 19/18639 0.0526315789473684 2.30823529411765 0.354971769884378 0.637908120027102 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/425 19/18639 0.0526315789473684 2.30823529411765 0.354971769884378 0.637908120027102 GO:0022821 solute:potassium antiporter activity 1/425 19/18639 0.0526315789473684 2.30823529411765 0.354971769884378 0.637908120027102 GO:0042577 lipid phosphatase activity 1/425 19/18639 0.0526315789473684 2.30823529411765 0.354971769884378 0.637908120027102 GO:0042800 histone H3K4 methyltransferase activity 1/425 19/18639 0.0526315789473684 2.30823529411765 0.354971769884378 0.637908120027102 GO:0050145 nucleoside monophosphate kinase activity 1/425 19/18639 0.0526315789473684 2.30823529411765 0.354971769884378 0.637908120027102 GO:0097001 ceramide binding 1/425 19/18639 0.0526315789473684 2.30823529411765 0.354971769884378 0.637908120027102 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 4/425 132/18639 0.0303030303030303 1.32898395721925 0.354972001484469 0.637908120027102 GO:0051219 phosphoprotein binding 3/425 93/18639 0.032258064516129 1.41472485768501 0.356347751347673 0.638818529854974 GO:0051087 protein-folding chaperone binding 4/425 134/18639 0.0298507462686567 1.30914837576822 0.365342721861708 0.648509422784159 GO:0030170 pyridoxal phosphate binding 2/425 56/18639 0.0357142857142857 1.5663025210084 0.366237142567377 0.648509422784159 GO:0170055 lipid transmembrane transporter activity 2/425 56/18639 0.0357142857142857 1.5663025210084 0.366237142567377 0.648509422784159 GO:0004721 phosphoprotein phosphatase activity 5/425 175/18639 0.0285714285714286 1.25304201680672 0.369203432408425 0.648509422784159 GO:0000339 RNA cap binding 1/425 20/18639 0.05 2.19282352941176 0.369694487274235 0.648509422784159 GO:0001614 purinergic nucleotide receptor activity 1/425 20/18639 0.05 2.19282352941176 0.369694487274235 0.648509422784159 GO:0016502 nucleotide receptor activity 1/425 20/18639 0.05 2.19282352941176 0.369694487274235 0.648509422784159 GO:0016505 peptidase activator activity involved in apoptotic process 1/425 20/18639 0.05 2.19282352941176 0.369694487274235 0.648509422784159 GO:0140939 histone H4 methyltransferase activity 1/425 20/18639 0.05 2.19282352941176 0.369694487274235 0.648509422784159 GO:0070279 vitamin B6 binding 2/425 57/18639 0.0350877192982456 1.53882352941176 0.374439310195043 0.654369046340294 GO:0099094 ligand-gated monoatomic cation channel activity 4/425 136/18639 0.0294117647058824 1.28989619377163 0.375705765381774 0.654369046340294 GO:0140789 histone phosphatase activity 4/425 136/18639 0.0294117647058824 1.28989619377163 0.375705765381774 0.654369046340294 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/425 21/18639 0.0476190476190476 2.08840336134454 0.384081932513423 0.656512140458991 GO:0005123 death receptor binding 1/425 21/18639 0.0476190476190476 2.08840336134454 0.384081932513423 0.656512140458991 GO:0005248 voltage-gated sodium channel activity 1/425 21/18639 0.0476190476190476 2.08840336134454 0.384081932513423 0.656512140458991 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/425 21/18639 0.0476190476190476 2.08840336134454 0.384081932513423 0.656512140458991 GO:0009975 cyclase activity 1/425 21/18639 0.0476190476190476 2.08840336134454 0.384081932513423 0.656512140458991 GO:0010314 phosphatidylinositol-5-phosphate binding 1/425 21/18639 0.0476190476190476 2.08840336134454 0.384081932513423 0.656512140458991 GO:0015125 bile acid transmembrane transporter activity 1/425 21/18639 0.0476190476190476 2.08840336134454 0.384081932513423 0.656512140458991 GO:0061891 calcium ion sensor activity 1/425 21/18639 0.0476190476190476 2.08840336134454 0.384081932513423 0.656512140458991 GO:0004879 nuclear receptor activity 2/425 59/18639 0.0338983050847458 1.48666001994018 0.390710626809141 0.666293064280089 GO:0004407 histone deacetylase activity 1/425 22/18639 0.0454545454545455 1.99347593582888 0.398141722967919 0.667653488612082 GO:0005243 gap junction channel activity 1/425 22/18639 0.0454545454545455 1.99347593582888 0.398141722967919 0.667653488612082 GO:0033558 protein lysine deacetylase activity 1/425 22/18639 0.0454545454545455 1.99347593582888 0.398141722967919 0.667653488612082 GO:0061133 endopeptidase activator activity 1/425 22/18639 0.0454545454545455 1.99347593582888 0.398141722967919 0.667653488612082 GO:0140517 protein-RNA adaptor activity 1/425 22/18639 0.0454545454545455 1.99347593582888 0.398141722967919 0.667653488612082 GO:0140784 metal ion sensor activity 1/425 22/18639 0.0454545454545455 1.99347593582888 0.398141722967919 0.667653488612082 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 2/425 60/18639 0.0333333333333333 1.46188235294118 0.39877534898055 0.667653488612082 GO:0098531 ligand-modulated transcription factor activity 2/425 60/18639 0.0333333333333333 1.46188235294118 0.39877534898055 0.667653488612082 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 2/425 61/18639 0.0327868852459016 1.43791706846673 0.406790034546489 0.672921933111953 GO:0016836 hydro-lyase activity 2/425 61/18639 0.0327868852459016 1.43791706846673 0.406790034546489 0.672921933111953 GO:0019905 syntaxin binding 2/425 61/18639 0.0327868852459016 1.43791706846673 0.406790034546489 0.672921933111953 GO:0004602 glutathione peroxidase activity 1/425 23/18639 0.0434782608695652 1.90680306905371 0.4118813033374 0.672921933111953 GO:0016849 phosphorus-oxygen lyase activity 1/425 23/18639 0.0434782608695652 1.90680306905371 0.4118813033374 0.672921933111953 GO:0017134 fibroblast growth factor binding 1/425 23/18639 0.0434782608695652 1.90680306905371 0.4118813033374 0.672921933111953 GO:0042171 lysophosphatidic acid acyltransferase activity 1/425 23/18639 0.0434782608695652 1.90680306905371 0.4118813033374 0.672921933111953 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 1/425 23/18639 0.0434782608695652 1.90680306905371 0.4118813033374 0.672921933111953 GO:0071617 lysophospholipid acyltransferase activity 1/425 23/18639 0.0434782608695652 1.90680306905371 0.4118813033374 0.672921933111953 GO:0099186 structural constituent of postsynapse 1/425 23/18639 0.0434782608695652 1.90680306905371 0.4118813033374 0.672921933111953 GO:0008238 exopeptidase activity 3/425 102/18639 0.0294117647058824 1.28989619377163 0.411993020272625 0.672921933111953 GO:0019903 protein phosphatase binding 4/425 144/18639 0.0277777777777778 1.21823529411765 0.416944332872492 0.678094019363702 GO:0015276 ligand-gated monoatomic ion channel activity 5/425 186/18639 0.0268817204301075 1.17893738140417 0.418905263669663 0.678094019363702 GO:0005507 copper ion binding 2/425 63/18639 0.0317460317460317 1.39226890756303 0.422661760496702 0.678094019363702 GO:0031406 carboxylic acid binding 5/425 187/18639 0.0267379679144385 1.17263290342875 0.423399990588961 0.678094019363702 GO:0001091 RNA polymerase II general transcription initiation factor binding 1/425 24/18639 0.0416666666666667 1.82735294117647 0.425307949560091 0.678094019363702 GO:0004622 lysophospholipase activity 1/425 24/18639 0.0416666666666667 1.82735294117647 0.425307949560091 0.678094019363702 GO:0030215 semaphorin receptor binding 1/425 24/18639 0.0416666666666667 1.82735294117647 0.425307949560091 0.678094019363702 GO:0035035 histone acetyltransferase binding 1/425 24/18639 0.0416666666666667 1.82735294117647 0.425307949560091 0.678094019363702 GO:0050431 transforming growth factor beta binding 1/425 24/18639 0.0416666666666667 1.82735294117647 0.425307949560091 0.678094019363702 GO:0070300 phosphatidic acid binding 1/425 24/18639 0.0416666666666667 1.82735294117647 0.425307949560091 0.678094019363702 GO:0070840 dynein complex binding 1/425 24/18639 0.0416666666666667 1.82735294117647 0.425307949560091 0.678094019363702 GO:0022834 ligand-gated channel activity 5/425 188/18639 0.0265957446808511 1.16639549436796 0.427888418770734 0.680731575317077 GO:0051020 GTPase binding 8/425 315/18639 0.0253968253968254 1.11381512605042 0.428971443733553 0.680980585624538 GO:0016791 phosphatase activity 7/425 273/18639 0.0256410256410256 1.12452488687783 0.43041357351866 0.681797363224601 GO:0015085 calcium ion transmembrane transporter activity 4/425 147/18639 0.0272108843537415 1.19337334933974 0.432263507520716 0.683255221565003 GO:0000149 SNARE binding 3/425 106/18639 0.0283018867924528 1.24122086570477 0.436265910839839 0.684172288498257 GO:0019843 rRNA binding 2/425 65/18639 0.0307692307692308 1.34942986425339 0.438311836784725 0.684172288498257 GO:0003707 nuclear steroid receptor activity 1/425 25/18639 0.04 1.75425882352941 0.438428772629495 0.684172288498257 GO:0005251 delayed rectifier potassium channel activity 1/425 25/18639 0.04 1.75425882352941 0.438428772629495 0.684172288498257 GO:0015271 outward rectifier potassium channel activity 1/425 25/18639 0.04 1.75425882352941 0.438428772629495 0.684172288498257 GO:0042974 nuclear retinoic acid receptor binding 1/425 25/18639 0.04 1.75425882352941 0.438428772629495 0.684172288498257 GO:0019888 protein phosphatase regulator activity 3/425 107/18639 0.0280373831775701 1.22962067069819 0.442276723872197 0.688714813656917 GO:0019842 vitamin binding 4/425 150/18639 0.0266666666666667 1.16950588235294 0.447472372006571 0.689541124550703 GO:0001217 DNA-binding transcription repressor activity 7/425 278/18639 0.0251798561151079 1.10429961912823 0.448957353290719 0.689541124550703 GO:0005112 Notch binding 1/425 26/18639 0.0384615384615385 1.68678733031674 0.451250722325018 0.689541124550703 GO:0005160 transforming growth factor beta receptor binding 1/425 26/18639 0.0384615384615385 1.68678733031674 0.451250722325018 0.689541124550703 GO:0008066 glutamate receptor activity 1/425 26/18639 0.0384615384615385 1.68678733031674 0.451250722325018 0.689541124550703 GO:0008157 protein phosphatase 1 binding 1/425 26/18639 0.0384615384615385 1.68678733031674 0.451250722325018 0.689541124550703 GO:0050681 nuclear androgen receptor binding 1/425 26/18639 0.0384615384615385 1.68678733031674 0.451250722325018 0.689541124550703 GO:0051139 metal cation:proton antiporter activity 1/425 26/18639 0.0384615384615385 1.68678733031674 0.451250722325018 0.689541124550703 GO:0120014 phospholipid transfer activity 1/425 26/18639 0.0384615384615385 1.68678733031674 0.451250722325018 0.689541124550703 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 2/425 67/18639 0.0298507462686567 1.30914837576822 0.453727970533226 0.690441797133193 GO:0042054 histone methyltransferase activity 2/425 67/18639 0.0298507462686567 1.30914837576822 0.453727970533226 0.690441797133193 GO:0008236 serine-type peptidase activity 5/425 194/18639 0.0257731958762887 1.13032140691328 0.454658271853694 0.690441797133193 GO:0005548 phospholipid transporter activity 2/425 68/18639 0.0294117647058824 1.28989619377163 0.461344895251535 0.691437594890315 GO:0030145 manganese ion binding 2/425 68/18639 0.0294117647058824 1.28989619377163 0.461344895251535 0.691437594890315 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/425 27/18639 0.037037037037037 1.6243137254902 0.463780590858402 0.691437594890315 GO:0008320 protein transmembrane transporter activity 1/425 27/18639 0.037037037037037 1.6243137254902 0.463780590858402 0.691437594890315 GO:0015252 proton channel activity 1/425 27/18639 0.037037037037037 1.6243137254902 0.463780590858402 0.691437594890315 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/425 27/18639 0.037037037037037 1.6243137254902 0.463780590858402 0.691437594890315 GO:0023026 MHC class II protein complex binding 1/425 27/18639 0.037037037037037 1.6243137254902 0.463780590858402 0.691437594890315 GO:0035255 ionotropic glutamate receptor binding 1/425 27/18639 0.037037037037037 1.6243137254902 0.463780590858402 0.691437594890315 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/425 27/18639 0.037037037037037 1.6243137254902 0.463780590858402 0.691437594890315 GO:0031267 small GTPase binding 7/425 283/18639 0.0247349823321555 1.0847890251507 0.467389430543476 0.69473604619169 GO:0016279 protein-lysine N-methyltransferase activity 2/425 69/18639 0.0289855072463768 1.27120204603581 0.468899421836939 0.69473604619169 GO:0017171 serine hydrolase activity 5/425 198/18639 0.0252525252525253 1.10748663101604 0.472316305429362 0.69473604619169 GO:0005242 inward rectifier potassium channel activity 1/425 28/18639 0.0357142857142857 1.5663025210084 0.476025016437876 0.69473604619169 GO:0045499 chemorepellent activity 1/425 28/18639 0.0357142857142857 1.5663025210084 0.476025016437876 0.69473604619169 GO:0046625 sphingolipid binding 1/425 28/18639 0.0357142857142857 1.5663025210084 0.476025016437876 0.69473604619169 GO:0051019 mitogen-activated protein kinase binding 1/425 28/18639 0.0357142857142857 1.5663025210084 0.476025016437876 0.69473604619169 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/425 28/18639 0.0357142857142857 1.5663025210084 0.476025016437876 0.69473604619169 GO:0097718 disordered domain specific binding 1/425 28/18639 0.0357142857142857 1.5663025210084 0.476025016437876 0.69473604619169 GO:0008028 monocarboxylic acid transmembrane transporter activity 2/425 70/18639 0.0285714285714286 1.25304201680672 0.476390431674302 0.69473604619169 GO:0016278 lysine N-methyltransferase activity 2/425 70/18639 0.0285714285714286 1.25304201680672 0.476390431674302 0.69473604619169 GO:0004629 phospholipase C activity 1/425 29/18639 0.0344827586206897 1.51229208924949 0.487990486751879 0.708839936289784 GO:0043236 laminin binding 1/425 29/18639 0.0344827586206897 1.51229208924949 0.487990486751879 0.708839936289784 GO:0045296 cadherin binding 8/425 334/18639 0.0239520958083832 1.05045438534695 0.494066031096365 0.713140304165048 GO:0015079 potassium ion transmembrane transporter activity 4/425 160/18639 0.025 1.09641176470588 0.497146827409078 0.713140304165048 GO:0099106 ion channel regulator activity 4/425 160/18639 0.025 1.09641176470588 0.497146827409078 0.713140304165048 GO:0003714 transcription corepressor activity 5/425 204/18639 0.0245098039215686 1.07491349480969 0.498448714101799 0.713140304165048 GO:0001965 G-protein alpha-subunit binding 1/425 30/18639 0.0333333333333333 1.46188235294118 0.499683342374149 0.713140304165048 GO:0016769 transferase activity, transferring nitrogenous groups 1/425 30/18639 0.0333333333333333 1.46188235294118 0.499683342374149 0.713140304165048 GO:0048019 receptor antagonist activity 1/425 30/18639 0.0333333333333333 1.46188235294118 0.499683342374149 0.713140304165048 GO:0070566 adenylyltransferase activity 1/425 30/18639 0.0333333333333333 1.46188235294118 0.499683342374149 0.713140304165048 GO:0098918 structural constituent of synapse 1/425 30/18639 0.0333333333333333 1.46188235294118 0.499683342374149 0.713140304165048 GO:0005164 tumor necrosis factor receptor binding 1/425 31/18639 0.032258064516129 1.41472485768501 0.511109780091973 0.723825989147592 GO:0016411 acylglycerol O-acyltransferase activity 1/425 31/18639 0.032258064516129 1.41472485768501 0.511109780091973 0.723825989147592 GO:0070273 phosphatidylinositol-4-phosphate binding 1/425 31/18639 0.032258064516129 1.41472485768501 0.511109780091973 0.723825989147592 GO:0072349 modified amino acid transmembrane transporter activity 1/425 31/18639 0.032258064516129 1.41472485768501 0.511109780091973 0.723825989147592 GO:0003725 double-stranded RNA binding 2/425 75/18639 0.0266666666666667 1.16950588235294 0.512859222227012 0.72490678526318 GO:0015631 tubulin binding 9/425 385/18639 0.0233766233766234 1.02521619556914 0.517130437199571 0.728743326866346 GO:0005261 monoatomic cation channel activity 8/425 341/18639 0.0234604105571848 1.0288908055891 0.517556485203038 0.728743326866346 GO:0022884 macromolecule transmembrane transporter activity 1/425 32/18639 0.03125 1.37051470588235 0.522275856159305 0.732581592131849 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/425 32/18639 0.03125 1.37051470588235 0.522275856159305 0.732581592131849 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 4/425 167/18639 0.0239520958083832 1.05045438534695 0.530759843348467 0.743063780687854 GO:0071889 14-3-3 protein binding 1/425 33/18639 0.0303030303030303 1.32898395721925 0.533187489476459 0.743629610560147 GO:0140416 transcription regulator inhibitor activity 1/425 33/18639 0.0303030303030303 1.32898395721925 0.533187489476459 0.743629610560147 GO:0016247 channel regulator activity 4/425 168/18639 0.0238095238095238 1.04420168067227 0.535472054064883 0.745401438897138 GO:0005267 potassium channel activity 3/425 124/18639 0.0241935483870968 1.06104364326376 0.539954071846569 0.748731826033591 GO:0016835 carbon-oxygen lyase activity 2/425 79/18639 0.0253164556962025 1.11029039463887 0.540805414010882 0.748731826033591 GO:0015035 protein-disulfide reductase activity 1/425 34/18639 0.0294117647058824 1.28989619377163 0.543850464698028 0.748731826033591 GO:0016831 carboxy-lyase activity 1/425 34/18639 0.0294117647058824 1.28989619377163 0.543850464698028 0.748731826033591 GO:0051427 hormone receptor binding 1/425 34/18639 0.0294117647058824 1.28989619377163 0.543850464698028 0.748731826033591 GO:0141108 transporter regulator activity 4/425 170/18639 0.0235294117647059 1.0319169550173 0.544825049118349 0.748731826033591 GO:0016741 transferase activity, transferring one-carbon groups 5/425 215/18639 0.0232558139534884 1.01991792065663 0.544995274731934 0.748731826033591 GO:0016229 steroid dehydrogenase activity 1/425 35/18639 0.0285714285714286 1.25304201680672 0.554270435270634 0.755940873196841 GO:0043015 gamma-tubulin binding 1/425 35/18639 0.0285714285714286 1.25304201680672 0.554270435270634 0.755940873196841 GO:0061631 ubiquitin conjugating enzyme activity 1/425 35/18639 0.0285714285714286 1.25304201680672 0.554270435270634 0.755940873196841 GO:0030971 receptor tyrosine kinase binding 2/425 81/18639 0.0246913580246914 1.08287581699346 0.55435664034435 0.755940873196841 GO:0005244 voltage-gated monoatomic ion channel activity 4/425 173/18639 0.023121387283237 1.01402244134648 0.558670341173884 0.760412408820009 GO:0141003 histone H2AX kinase activity 8/425 354/18639 0.0225988700564972 0.99110667996012 0.560134715356586 0.760996332323643 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/425 36/18639 0.0277777777777778 1.21823529411765 0.56445292640211 0.762069410475224 GO:0045505 dynein intermediate chain binding 1/425 36/18639 0.0277777777777778 1.21823529411765 0.56445292640211 0.762069410475224 GO:0055106 ubiquitin-protein transferase regulator activity 1/425 36/18639 0.0277777777777778 1.21823529411765 0.56445292640211 0.762069410475224 GO:0022832 voltage-gated channel activity 4/425 175/18639 0.0228571428571429 1.00243361344538 0.567773654352811 0.762069410475224 GO:0140996 histone H3 kinase activity 8/425 357/18639 0.0224089635854342 0.98277805239743 0.569734705175311 0.762069410475224 GO:0005216 monoatomic ion channel activity 10/425 448/18639 0.0223214285714286 0.978939075630252 0.57219278325572 0.762069410475224 GO:0004252 serine-type endopeptidase activity 4/425 176/18639 0.0227272727272727 0.996737967914438 0.572286272892147 0.762069410475224 GO:0004527 exonuclease activity 2/425 84/18639 0.0238095238095238 1.04420168067227 0.57414821202476 0.762069410475224 GO:0051117 ATPase binding 2/425 84/18639 0.0238095238095238 1.04420168067227 0.57414821202476 0.762069410475224 GO:0019213 deacetylase activity 1/425 37/18639 0.027027027027027 1.18531001589825 0.574403337963638 0.762069410475224 GO:0023023 MHC protein complex binding 1/425 37/18639 0.027027027027027 1.18531001589825 0.574403337963638 0.762069410475224 GO:0030280 structural constituent of skin epidermis 1/425 37/18639 0.027027027027027 1.18531001589825 0.574403337963638 0.762069410475224 GO:0030551 cyclic nucleotide binding 1/425 37/18639 0.027027027027027 1.18531001589825 0.574403337963638 0.762069410475224 GO:0005262 calcium channel activity 3/425 131/18639 0.0229007633587786 1.00434665469241 0.577231923696105 0.763912917320758 GO:0046873 metal ion transmembrane transporter activity 10/425 450/18639 0.0222222222222222 0.974588235294118 0.577871540177335 0.763912917320758 GO:0035173 histone kinase activity 8/425 360/18639 0.0222222222222222 0.974588235294118 0.579240964852874 0.763938267410816 GO:0000146 microfilament motor activity 1/425 38/18639 0.0263157894736842 1.15411764705882 0.584126947326365 0.763938267410816 GO:0005501 retinoid binding 1/425 38/18639 0.0263157894736842 1.15411764705882 0.584126947326365 0.763938267410816 GO:0019840 isoprenoid binding 1/425 38/18639 0.0263157894736842 1.15411764705882 0.584126947326365 0.763938267410816 GO:0042887 amide transmembrane transporter activity 1/425 38/18639 0.0263157894736842 1.15411764705882 0.584126947326365 0.763938267410816 GO:0043531 ADP binding 1/425 38/18639 0.0263157894736842 1.15411764705882 0.584126947326365 0.763938267410816 GO:0016853 isomerase activity 4/425 180/18639 0.0222222222222222 0.974588235294118 0.590069636744554 0.769627230100682 GO:0022836 gated channel activity 7/425 318/18639 0.0220125786163522 0.965394006659267 0.590571099016034 0.769627230100682 GO:0000217 DNA secondary structure binding 1/425 39/18639 0.0256410256410256 1.12452488687783 0.593628912133972 0.77087853430825 GO:0016776 phosphotransferase activity, phosphate group as acceptor 1/425 39/18639 0.0256410256410256 1.12452488687783 0.593628912133972 0.77087853430825 GO:0015297 antiporter activity 3/425 135/18639 0.0222222222222222 0.974588235294118 0.597665232893496 0.774751227824902 GO:0015036 disulfide oxidoreductase activity 1/425 40/18639 0.025 1.09641176470588 0.602914273012632 0.780179561028669 GO:0003727 single-stranded RNA binding 2/425 89/18639 0.0224719101123595 0.985538664904164 0.605694893024159 0.782400257245619 GO:0008237 metallopeptidase activity 4/425 184/18639 0.0217391304347826 0.953401534526854 0.607413079428397 0.783243181368196 GO:0042169 SH2 domain binding 1/425 41/18639 0.024390243902439 1.0696700143472 0.611987956219773 0.785010729182432 GO:0061650 ubiquitin-like protein conjugating enzyme activity 1/425 41/18639 0.024390243902439 1.0696700143472 0.611987956219773 0.785010729182432 GO:0140318 protein transporter activity 1/425 41/18639 0.024390243902439 1.0696700143472 0.611987956219773 0.785010729182432 GO:0008234 cysteine-type peptidase activity 4/425 187/18639 0.0213903743315508 0.938106322743001 0.620123213415729 0.79223656342236 GO:0031492 nucleosomal DNA binding 1/425 42/18639 0.0238095238095238 1.04420168067227 0.620854776233033 0.79223656342236 GO:0035198 miRNA binding 1/425 42/18639 0.0238095238095238 1.04420168067227 0.620854776233033 0.79223656342236 GO:0046943 carboxylic acid transmembrane transporter activity 4/425 188/18639 0.0212765957446809 0.933116395494368 0.62430223069062 0.795255007898796 GO:0005342 organic acid transmembrane transporter activity 4/425 189/18639 0.0211640211640212 0.928179271708684 0.628452116103895 0.797753081269541 GO:0005245 voltage-gated calcium channel activity 1/425 43/18639 0.0232558139534884 1.01991792065663 0.629519438280726 0.797753081269541 GO:0008200 ion channel inhibitor activity 1/425 43/18639 0.0232558139534884 1.01991792065663 0.629519438280726 0.797753081269541 GO:0022843 voltage-gated monoatomic cation channel activity 3/425 143/18639 0.020979020979021 0.920065816536405 0.636555286029637 0.802945389553351 GO:0001223 transcription coactivator binding 1/425 44/18639 0.0227272727272727 0.996737967914438 0.637986540815179 0.802945389553351 GO:0016248 channel inhibitor activity 1/425 44/18639 0.0227272727272727 0.996737967914438 0.637986540815179 0.802945389553351 GO:0019205 nucleobase-containing compound kinase activity 1/425 44/18639 0.0227272727272727 0.996737967914438 0.637986540815179 0.802945389553351 GO:0008276 protein methyltransferase activity 2/425 95/18639 0.0210526315789474 0.923294117647059 0.641174376495379 0.805087330133368 GO:0008194 UDP-glycosyltransferase activity 3/425 145/18639 0.0206896551724138 0.907375253549696 0.645858128256715 0.805087330133368 GO:0042605 peptide antigen binding 1/425 45/18639 0.0222222222222222 0.974588235294118 0.646260577930186 0.805087330133368 GO:0046915 transition metal ion transmembrane transporter activity 1/425 45/18639 0.0222222222222222 0.974588235294118 0.646260577930186 0.805087330133368 GO:0140303 intramembrane lipid transporter activity 1/425 45/18639 0.0222222222222222 0.974588235294118 0.646260577930186 0.805087330133368 GO:0141110 transporter inhibitor activity 1/425 45/18639 0.0222222222222222 0.974588235294118 0.646260577930186 0.805087330133368 GO:0030594 neurotransmitter receptor activity 2/425 97/18639 0.0206185567010309 0.904257125530625 0.652429265289908 0.811396802010292 GO:0005249 voltage-gated potassium channel activity 2/425 98/18639 0.0204081632653061 0.895030012004802 0.657950594571725 0.816881228057801 GO:0001784 phosphotyrosine residue binding 1/425 47/18639 0.0212765957446809 0.933116395494368 0.662246924608142 0.818069730398293 GO:0140359 ABC-type transporter activity 1/425 47/18639 0.0212765957446809 0.933116395494368 0.662246924608142 0.818069730398293 GO:0140938 histone H3 methyltransferase activity 1/425 47/18639 0.0212765957446809 0.933116395494368 0.662246924608142 0.818069730398293 GO:0140693 molecular condensate scaffold activity 1/425 48/18639 0.0208333333333333 0.913676470588235 0.669967721566056 0.826218582803777 GO:0035254 glutamate receptor binding 1/425 49/18639 0.0204081632653061 0.895030012004802 0.677512432358075 0.834123346370495 GO:0015171 amino acid transmembrane transporter activity 2/425 102/18639 0.0196078431372549 0.859930795847751 0.679335879239319 0.83496968434933 GO:0032813 tumor necrosis factor receptor superfamily binding 1/425 50/18639 0.02 0.877129411764706 0.68488506367856 0.840384844413592 GO:0008168 methyltransferase activity 4/425 204/18639 0.0196078431372549 0.859930795847751 0.687121222757014 0.841723497877342 GO:0005272 sodium channel activity 1/425 51/18639 0.0196078431372549 0.859930795847751 0.692089531263509 0.84499303235661 GO:0030544 Hsp70 protein binding 1/425 51/18639 0.0196078431372549 0.859930795847751 0.692089531263509 0.84499303235661 GO:0030159 signaling receptor complex adaptor activity 1/425 52/18639 0.0192307692307692 0.843393665158371 0.699129661950673 0.851357676511401 GO:0004497 monooxygenase activity 2/425 106/18639 0.0188679245283019 0.827480577136515 0.699619097432498 0.851357676511401 GO:0004864 protein phosphatase inhibitor activity 1/425 53/18639 0.0188679245283019 0.827480577136515 0.706009195693126 0.852080063767566 GO:0005246 calcium channel regulator activity 1/425 53/18639 0.0188679245283019 0.827480577136515 0.706009195693126 0.852080063767566 GO:0008146 sulfotransferase activity 1/425 53/18639 0.0188679245283019 0.827480577136515 0.706009195693126 0.852080063767566 GO:0140296 general transcription initiation factor binding 1/425 53/18639 0.0188679245283019 0.827480577136515 0.706009195693126 0.852080063767566 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 1/425 53/18639 0.0188679245283019 0.827480577136515 0.706009195693126 0.852080063767566 GO:0003925 G protein activity 1/425 54/18639 0.0185185185185185 0.812156862745098 0.712731787527325 0.855976901687228 GO:0050661 NADP binding 1/425 54/18639 0.0185185185185185 0.812156862745098 0.712731787527325 0.855976901687228 GO:0140463 chromatin-protein adaptor activity 1/425 54/18639 0.0185185185185185 0.812156862745098 0.712731787527325 0.855976901687228 GO:0004620 phospholipase activity 2/425 109/18639 0.018348623853211 0.804705882352941 0.714124769757323 0.856250743510004 GO:0008374 O-acyltransferase activity 1/425 55/18639 0.0181818181818182 0.797390374331551 0.719301009496703 0.861052511368203 GO:0019212 phosphatase inhibitor activity 1/425 56/18639 0.0178571428571429 0.783151260504202 0.725720352531781 0.864591181620156 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/425 56/18639 0.0178571428571429 0.783151260504202 0.725720352531781 0.864591181620156 GO:0015081 sodium ion transmembrane transporter activity 3/425 164/18639 0.0182926829268293 0.802252510760402 0.725786066747805 0.864591181620156 GO:0016757 glycosyltransferase activity 5/425 267/18639 0.0187265917602996 0.82128222075347 0.731632589656435 0.870145555659352 GO:0008514 organic anion transmembrane transporter activity 5/425 269/18639 0.0185873605947955 0.815176033238574 0.737555355513402 0.87503287684108 GO:0061980 regulatory RNA binding 1/425 58/18639 0.0172413793103448 0.756146044624746 0.738122970940775 0.87503287684108 GO:0001221 transcription coregulator binding 2/425 115/18639 0.0173913043478261 0.762721227621483 0.74137605995973 0.877474080628666 GO:0015459 potassium channel regulator activity 1/425 59/18639 0.0169491525423729 0.74333000997009 0.744112838943045 0.877885933584491 GO:0045309 protein phosphorylated amino acid binding 1/425 59/18639 0.0169491525423729 0.74333000997009 0.744112838943045 0.877885933584491 GO:0001098 basal transcription machinery binding 1/425 60/18639 0.0166666666666667 0.730941176470588 0.749966016739019 0.881960035685087 GO:0001099 basal RNA polymerase II transcription machinery binding 1/425 60/18639 0.0166666666666667 0.730941176470588 0.749966016739019 0.881960035685087 GO:0008017 microtubule binding 5/425 276/18639 0.0181159420289855 0.794501278772379 0.757532933924095 0.889435633281485 GO:0015179 L-amino acid transmembrane transporter activity 1/425 62/18639 0.0161290322580645 0.707362428842505 0.761274679474419 0.892403332398243 GO:0022824 transmitter-gated monoatomic ion channel activity 1/425 63/18639 0.0158730158730159 0.696134453781513 0.766736178167609 0.894525541195543 GO:0022835 transmitter-gated channel activity 1/425 63/18639 0.0158730158730159 0.696134453781513 0.766736178167609 0.894525541195543 GO:1901682 sulfur compound transmembrane transporter activity 1/425 63/18639 0.0158730158730159 0.696134453781513 0.766736178167609 0.894525541195543 GO:0000287 magnesium ion binding 4/425 230/18639 0.0173913043478261 0.762721227621483 0.772654098310396 0.900001208016071 GO:0160215 deacylase activity 1/425 65/18639 0.0153846153846154 0.674714932126697 0.77728803577592 0.903966307429275 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 3/425 181/18639 0.0165745856353591 0.726902827429314 0.784711840646618 0.904542560222383 GO:0015291 secondary active transmembrane transporter activity 5/425 287/18639 0.0174216027874564 0.764050010248002 0.786593087921866 0.904542560222383 GO:0031490 chromatin DNA binding 2/425 128/18639 0.015625 0.685257352941177 0.792870144145512 0.904542560222383 GO:0098960 postsynaptic neurotransmitter receptor activity 1/425 69/18639 0.0144927536231884 0.635601023017903 0.796984451742182 0.904542560222383 GO:0016298 lipase activity 2/425 130/18639 0.0153846153846154 0.674714932126697 0.799937063661075 0.904542560222383 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 2/425 130/18639 0.0153846153846154 0.674714932126697 0.799937063661075 0.904542560222383 GO:0016782 transferase activity, transferring sulphur-containing groups 1/425 70/18639 0.0142857142857143 0.626521008403361 0.801630741888093 0.904542560222383 GO:0140299 molecular sensor activity 1/425 71/18639 0.0140845070422535 0.617696768848384 0.806170939782302 0.904542560222383 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 4/425 243/18639 0.0164609053497942 0.721917211328976 0.807973440726541 0.904542560222383 GO:0004676 3-phosphoinositide-dependent protein kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.904542560222383 GO:0004711 ribosomal protein S6 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.904542560222383 GO:0035175 histone H3S10 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.904542560222383 GO:0035979 histone H2AXS139 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.904542560222383 GO:0044022 histone H3S28 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.904542560222383 GO:0044023 histone H4S1 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.904542560222383 GO:0044024 histone H2AS1 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.904542560222383 GO:0044025 histone H2BS14 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.904542560222383 GO:0072354 histone H3T3 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.904542560222383 GO:0072371 histone H2AS121 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.904542560222383 GO:0072518 Rho-dependent protein serine/threonine kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.904542560222383 GO:0140823 histone H2BS36 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.904542560222383 GO:0140855 histone H3S57 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.904542560222383 GO:0140995 histone H2A kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.904542560222383 GO:0140997 histone H4 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.904542560222383 GO:0140998 histone H2B kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.904542560222383 GO:1990244 histone H2AT120 kinase activity 4/425 245/18639 0.0163265306122449 0.716024009603842 0.812990848835718 0.904542560222383 GO:0004521 RNA endonuclease activity 1/425 73/18639 0.0136986301369863 0.600773569701853 0.814942671488091 0.904542560222383 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/425 73/18639 0.0136986301369863 0.600773569701853 0.814942671488091 0.904542560222383 GO:0004677 DNA-dependent protein kinase activity 4/425 246/18639 0.016260162601626 0.713113342898135 0.815459144024228 0.904542560222383 GO:0140857 histone H3T45 kinase activity 4/425 246/18639 0.016260162601626 0.713113342898135 0.815459144024228 0.904542560222383 GO:0035402 histone H3T11 kinase activity 4/425 247/18639 0.0161943319838057 0.710226244343891 0.817900717336463 0.904542560222383 GO:0035403 histone H3T6 kinase activity 4/425 247/18639 0.0161943319838057 0.710226244343891 0.817900717336463 0.904542560222383 GO:0031491 nucleosome binding 1/425 74/18639 0.0135135135135135 0.592655007949126 0.819178875550225 0.904542560222383 GO:0004679 AMP-activated protein kinase activity 4/425 248/18639 0.0161290322580645 0.707362428842505 0.820315734279985 0.904542560222383 GO:0031625 ubiquitin protein ligase binding 5/425 302/18639 0.0165562913907285 0.726100506427737 0.821779123039533 0.904542560222383 GO:0016922 nuclear receptor binding 2/425 137/18639 0.0145985401459854 0.640240446543581 0.823015878498629 0.904542560222383 GO:0019003 GDP binding 1/425 75/18639 0.0133333333333333 0.584752941176471 0.823318330324862 0.904542560222383 GO:0017022 myosin binding 1/425 76/18639 0.0131578947368421 0.577058823529412 0.827363240344898 0.907629823363433 GO:0140767 enzyme-substrate adaptor activity 2/425 139/18639 0.0143884892086331 0.631028353787558 0.829157030710448 0.908061841843587 GO:0016758 hexosyltransferase activity 3/425 197/18639 0.0152284263959391 0.667865034338609 0.830227969685566 0.908061841843587 GO:0003713 transcription coactivator activity 4/425 256/18639 0.015625 0.685257352941177 0.838700279860012 0.915965387365689 GO:0015101 organic cation transmembrane transporter activity 1/425 81/18639 0.0123456790123457 0.541437908496732 0.846243332559684 0.922832120818053 GO:0003730 mRNA 3'-UTR binding 4/425 262/18639 0.0152671755725191 0.669564436461608 0.851434168296816 0.926301169350142 GO:0005254 chloride channel activity 1/425 83/18639 0.0120481927710843 0.528391211906449 0.853205294761967 0.926301169350142 GO:0030165 PDZ domain binding 1/425 83/18639 0.0120481927710843 0.528391211906449 0.853205294761967 0.926301169350142 GO:0004518 nuclease activity 3/425 209/18639 0.0143540669856459 0.62951871657754 0.858721600035032 0.930915008887535 GO:0044389 ubiquitin-like protein ligase binding 5/425 322/18639 0.015527950310559 0.68100109609061 0.861263174820707 0.931764017415899 GO:0050660 flavin adenine dinucleotide binding 1/425 86/18639 0.0116279069767442 0.509958960328317 0.863062962719482 0.931764017415899 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 4/425 268/18639 0.0149253731343284 0.654574187884109 0.863307885524119 0.931764017415899 GO:0003924 GTPase activity 5/425 331/18639 0.0151057401812689 0.662484449973343 0.876491670814329 0.944606126170868 GO:0003712 transcription coregulator activity 8/425 495/18639 0.0161616161616162 0.708791443850267 0.880540743974223 0.946517643460302 GO:0052689 carboxylic ester hydrolase activity 1/425 92/18639 0.0108695652173913 0.476700767263427 0.880840909016118 0.946517643460302 GO:0016410 N-acyltransferase activity 1/425 94/18639 0.0106382978723404 0.466558197747184 0.886239487342624 0.950928501017268 GO:0016407 acetyltransferase activity 1/425 96/18639 0.0104166666666667 0.456838235294118 0.891394029056009 0.955065031131439 GO:0042626 ATPase-coupled transmembrane transporter activity 1/425 98/18639 0.0102040816326531 0.447515006002401 0.896315540714039 0.955467506451973 GO:0019001 guanyl nucleotide binding 6/425 400/18639 0.015 0.657847058823529 0.896688608771568 0.955467506451973 GO:0032561 guanyl ribonucleotide binding 6/425 400/18639 0.015 0.657847058823529 0.896688608771568 0.955467506451973 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 3/425 229/18639 0.0131004366812227 0.574538916003082 0.896969495852873 0.955467506451973 GO:0005253 monoatomic anion channel activity 1/425 103/18639 0.00970873786407767 0.425790976584809 0.907667634585553 0.964263045827303 GO:0061630 ubiquitin protein ligase activity 5/425 353/18639 0.0141643059490085 0.621196467255457 0.907850377840128 0.964263045827303 GO:0003823 antigen binding 2/425 174/18639 0.0114942528735632 0.504097363083164 0.909584270537386 0.964710589963895 GO:0106310 protein serine kinase activity 5/425 361/18639 0.0138504155124654 0.607430340557276 0.917399783594536 0.971597753518709 GO:0061659 ubiquitin-like protein ligase activity 5/425 372/18639 0.0134408602150538 0.589468690702087 0.929104879791985 0.982578541938286 GO:0004674 protein serine/threonine kinase activity 6/425 433/18639 0.0138568129330254 0.607710908843907 0.932452070523159 0.983404605185851 GO:0016755 aminoacyltransferase activity 7/425 496/18639 0.0141129032258065 0.618942125237192 0.937884367528641 0.983404605185851 GO:0003697 single-stranded DNA binding 1/425 121/18639 0.00826446280991736 0.362450170150705 0.93919417812343 0.983404605185851 GO:0004540 RNA nuclease activity 1/425 121/18639 0.00826446280991736 0.362450170150705 0.93919417812343 0.983404605185851 GO:0015108 chloride transmembrane transporter activity 1/425 121/18639 0.00826446280991736 0.362450170150705 0.93919417812343 0.983404605185851 GO:0051082 unfolded protein binding 1/425 121/18639 0.00826446280991736 0.362450170150705 0.93919417812343 0.983404605185851 GO:0008528 G protein-coupled peptide receptor activity 1/425 122/18639 0.00819672131147541 0.359479267116683 0.940589710810413 0.983404605185851 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 1/425 122/18639 0.00819672131147541 0.359479267116683 0.940589710810413 0.983404605185851 GO:0004842 ubiquitin-protein transferase activity 6/425 449/18639 0.0133630289532294 0.586055286257042 0.945480194973851 0.987107540545791 GO:0004519 endonuclease activity 1/425 127/18639 0.0078740157480315 0.345326540064845 0.947102406064835 0.987107540545791 GO:0001653 peptide receptor activity 1/425 128/18639 0.0078125 0.342628676470588 0.948316833324043 0.987107540545791 GO:0035591 signaling adaptor activity 1/425 129/18639 0.00775193798449612 0.339972640218878 0.949503443763094 0.987107540545791 GO:0031072 heat shock protein binding 1/425 131/18639 0.00763358778625954 0.334782218230804 0.951795742424191 0.98809303768613 GO:0016779 nucleotidyltransferase activity 1/425 136/18639 0.00735294117647059 0.322474048442907 0.957082458092868 0.989903948196354 GO:0016887 ATP hydrolysis activity 5/425 417/18639 0.0119904076738609 0.525856961489632 0.963049080694435 0.989903948196354 GO:0019787 ubiquitin-like protein transferase activity 6/425 479/18639 0.0125260960334029 0.549350362274346 0.964001558013298 0.989903948196354 GO:0008509 monoatomic anion transmembrane transporter activity 1/425 149/18639 0.00671140939597315 0.294338728780103 0.968275205911213 0.989903948196354 GO:0000510 H3-H4 histone complex chaperone activity 1/425 151/18639 0.00662251655629139 0.290440202571095 0.969716897338123 0.989903948196354 GO:0140584 chromatin extrusion motor activity 1/425 151/18639 0.00662251655629139 0.290440202571095 0.969716897338123 0.989903948196354 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 1/425 151/18639 0.00662251655629139 0.290440202571095 0.969716897338123 0.989903948196354 GO:0140849 ATP-dependent H2AZ histone chaperone activity 1/425 151/18639 0.00662251655629139 0.290440202571095 0.969716897338123 0.989903948196354 GO:0015616 DNA translocase activity 1/425 152/18639 0.00657894736842105 0.288529411764706 0.970413041790271 0.989903948196354 GO:0140674 ATP-dependent histone chaperone activity 1/425 152/18639 0.00657894736842105 0.288529411764706 0.970413041790271 0.989903948196354 GO:0003774 cytoskeletal motor activity 1/425 153/18639 0.0065359477124183 0.286643598615917 0.971093220144743 0.989903948196354 GO:0061775 cohesin loader activity 1/425 153/18639 0.0065359477124183 0.286643598615917 0.971093220144743 0.989903948196354 GO:0140658 ATP-dependent chromatin remodeler activity 1/425 158/18639 0.00632911392405063 0.277572598659717 0.974267119365443 0.989903948196354 GO:0005525 GTP binding 4/425 378/18639 0.0105820105820106 0.464089635854342 0.974567820481927 0.989903948196354 GO:0003689 DNA clamp loader activity 1/425 160/18639 0.00625 0.274102941176471 0.975437079059385 0.989903948196354 GO:0140713 histone chaperone activity 1/425 164/18639 0.00609756097560976 0.267417503586801 0.977620180416838 0.989903948196354 GO:0042393 histone binding 2/425 247/18639 0.00809716599190283 0.355113122171946 0.977906199244493 0.989903948196354 GO:0015103 inorganic anion transmembrane transporter activity 1/425 165/18639 0.00606060606060606 0.26579679144385 0.978135007119022 0.989903948196354 GO:0016874 ligase activity 1/425 167/18639 0.00598802395209581 0.262613596336738 0.97912948345408 0.989903948196354 GO:0140030 modification-dependent protein binding 1/425 173/18639 0.00578034682080925 0.25350561033662 0.981850215126951 0.991291082580095 GO:0043021 ribonucleoprotein complex binding 1/425 177/18639 0.00564971751412429 0.24777666999003 0.98346442664452 0.991558784065462 GO:0140597 protein carrier chaperone 1/425 188/18639 0.00531914893617021 0.233279098873592 0.98720235949879 0.993964019495357 GO:0008094 ATP-dependent activity, acting on DNA 1/425 210/18639 0.00476190476190476 0.208840336134454 0.992337867018416 0.997767896386506 GO:0030371 translation repressor activity 1/425 329/18639 0.00303951367781155 0.133302342213481 0.999527254055639 0.999879182746287 GO:0140097 catalytic activity, acting on DNA 1/425 336/18639 0.00297619047619048 0.130525210084034 0.999598930003764 0.999879182746287 GO:0045182 translation regulator activity 1/425 356/18639 0.00280898876404494 0.12319233311302 0.999749362535562 0.999879182746287 GO:0140098 catalytic activity, acting on RNA 1/425 387/18639 0.00258397932816537 0.113324213406293 0.999879182746287 0.999879182746287