ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 78/789 175/18639 0.445714285714286 10.5293644758284 4.21773972733974e-60 3.83814315187917e-57 GO:0015078 proton transmembrane transporter activity 54/789 185/18639 0.291891891891892 6.8955297502826 1.353942945283e-30 6.16044040103766e-28 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 34/789 68/18639 0.5 11.8117870722433 7.34755815441023e-29 2.22875930683777e-26 GO:0009055 electron transfer activity 39/789 116/18639 0.336206896551724 7.94240854857742 5.73656813297512e-25 1.30506925025184e-22 GO:0022853 active monoatomic ion transmembrane transporter activity 39/789 118/18639 0.330508474576271 7.80779145453374 1.18602211921565e-24 2.15856025697249e-22 GO:0003954 NADH dehydrogenase activity 23/789 44/18639 0.522727272727273 12.348686484618 1.64160175529257e-20 2.48976266219373e-18 GO:0008137 NADH dehydrogenase (ubiquinone) activity 22/789 41/18639 0.536585365853659 12.6760641750904 5.25236853733791e-20 6.82807909853928e-18 GO:0015399 primary active transmembrane transporter activity 40/789 166/18639 0.240963855421687 5.69242750469559 1.31333780912084e-19 1.49392175787495e-17 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 22/789 58/18639 0.379310344827586 8.9606660548053 6.0963173959224e-16 6.16405425587709e-14 GO:0016651 oxidoreductase activity, acting on NAD(P)H 25/789 88/18639 0.284090909090909 6.71124265468372 1.53347690748063e-14 1.39546398580737e-12 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 10/789 18/18639 0.555555555555556 13.1242078580482 5.61388203571664e-10 4.64421150227467e-08 GO:0022804 active transmembrane transporter activity 50/789 457/18639 0.109409190371991 2.58463612084099 7.97492042548271e-10 6.04764798932439e-08 GO:0004129 cytochrome-c oxidase activity 9/789 15/18639 0.6 14.174144486692 1.66053699307304e-09 1.16237589515113e-07 GO:0016675 oxidoreductase activity, acting on a heme group of donors 9/789 16/18639 0.5625 13.2882604562738 3.65279666759504e-09 2.37431783393678e-07 GO:0019843 rRNA binding 16/789 65/18639 0.246153846153846 5.81503363556596 8.4811226157553e-09 5.14521438689155e-07 GO:0031386 protein tag activity 8/789 15/18639 0.533333333333333 12.5992395437262 4.91686601407016e-08 2.48574892933547e-06 GO:0055105 ubiquitin-protein transferase inhibitor activity 8/789 15/18639 0.533333333333333 12.5992395437262 4.91686601407016e-08 2.48574892933547e-06 GO:0141047 molecular tag activity 8/789 15/18639 0.533333333333333 12.5992395437262 4.91686601407016e-08 2.48574892933547e-06 GO:1990948 ubiquitin ligase inhibitor activity 7/789 11/18639 0.636363636363636 15.0331835464915 6.74606999348888e-08 3.23101247056573e-06 GO:0015252 proton channel activity 10/789 27/18639 0.37037037037037 8.74947190536544 7.64560433508555e-08 3.47874997246392e-06 GO:0016209 antioxidant activity 17/789 86/18639 0.197674418604651 4.66977628437528 9.71901534103588e-08 4.21157331444888e-06 GO:0031720 haptoglobin binding 6/789 10/18639 0.6 14.174144486692 1.02462470650587e-06 4.23822037691063e-05 GO:0004601 peroxidase activity 12/789 57/18639 0.210526315789474 4.97338403041825 3.72108315381681e-06 0.000147225463911883 GO:0031625 ubiquitin protein ligase binding 31/789 302/18639 0.102649006622517 2.42493641880493 5.1524199245624e-06 0.000195362588806324 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 12/789 59/18639 0.203389830508475 4.80479474125153 5.44921309997414e-06 0.000198351356839059 GO:0005201 extracellular matrix structural constituent 21/789 168/18639 0.125 2.95294676806084 8.90972662697601e-06 0.00031184043194416 GO:0005344 oxygen carrier activity 6/789 14/18639 0.428571428571429 10.1243889190657 1.26602013023111e-05 0.000426695673522338 GO:0044389 ubiquitin-like protein ligase binding 31/789 322/18639 0.0962732919254658 2.27431924993505 1.86625218387902e-05 0.000606531959760683 GO:0045296 cadherin binding 31/789 334/18639 0.092814371257485 2.19260718107511 3.78848841713874e-05 0.00118880153779181 GO:0048027 mRNA 5'-UTR binding 7/789 24/18639 0.291666666666667 6.89020912547528 4.36262198148046e-05 0.00132332866771574 GO:0019864 IgG binding 5/789 11/18639 0.454545454545455 10.737988247494 5.01034533179241e-05 0.00147077879094551 GO:0038024 cargo receptor activity 11/789 65/18639 0.169230769230769 3.99783562445159 8.06879422548773e-05 0.00229456335787307 GO:0055106 ubiquitin-protein transferase regulator activity 8/789 36/18639 0.222222222222222 5.24968314321926 0.000104827948737679 0.00289071010155417 GO:0016504 peptidase activator activity 10/789 57/18639 0.175438596491228 4.14448669201521 0.000123796613153119 0.00331337994027466 GO:0005178 integrin binding 18/789 161/18639 0.111801242236025 2.64114493540845 0.000164874881850605 0.00428674692811574 GO:0019763 immunoglobulin receptor activity 5/789 14/18639 0.357142857142857 8.4369907658881 0.000195220572277232 0.00493474224367447 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 8/789 40/18639 0.2 4.72471482889734 0.000229375116278152 0.00564138799494914 GO:0030020 extracellular matrix structural constituent conferring tensile strength 8/789 44/18639 0.181818181818182 4.29519529899758 0.000455274244258149 0.0109026200598662 GO:0008009 chemokine activity 8/789 45/18639 0.177777777777778 4.19974651457541 0.00053344677193517 0.012447091345154 GO:0005044 scavenger receptor activity 6/789 27/18639 0.222222222222222 5.24968314321926 0.000778682353842426 0.0177150235499152 GO:0048407 platelet-derived growth factor binding 4/789 11/18639 0.363636363636364 8.59039059799516 0.000828326434484662 0.0180946594803749 GO:0038187 pattern recognition receptor activity 8/789 48/18639 0.166666666666667 3.93726235741445 0.000835138129863458 0.0180946594803749 GO:0003785 actin monomer binding 6/789 29/18639 0.206896551724138 4.8876360298938 0.00116266492132884 0.0246052343816103 GO:0016505 peptidase activator activity involved in apoptotic process 5/789 20/18639 0.25 5.90589353612167 0.00122357323369661 0.0253057191514527 GO:0005080 protein kinase C binding 8/789 52/18639 0.153846153846154 3.63439602222872 0.00143543450268138 0.0290276754986679 GO:0061134 peptidase regulator activity 20/789 226/18639 0.0884955752212389 2.09058178269794 0.00154467717260922 0.0305577440668346 GO:0035325 Toll-like receptor binding 4/789 13/18639 0.307692307692308 7.26879204445744 0.00167704931593672 0.031794059947967 GO:0070700 BMP receptor binding 4/789 13/18639 0.307692307692308 7.26879204445744 0.00167704931593672 0.031794059947967 GO:0004857 enzyme inhibitor activity 31/789 416/18639 0.0745192307692308 1.76041057326704 0.00171779322673745 0.0319018742108384 GO:0031681 G-protein beta-subunit binding 5/789 23/18639 0.217391304347826 5.13555959662754 0.00239030984428395 0.0435036391659678 GO:0001540 amyloid-beta binding 10/789 83/18639 0.120481927710843 2.84621375234779 0.0025997547415863 0.0454957079777602 GO:0008135 translation factor activity, RNA binding 10/789 83/18639 0.120481927710843 2.84621375234779 0.0025997547415863 0.0454957079777602 GO:0019825 oxygen binding 6/789 34/18639 0.176470588235294 4.16886602549765 0.0027504407870598 0.0472245493627249 GO:0180051 translation factor activity 10/789 84/18639 0.119047619047619 2.81233025529603 0.00284183585304148 0.0478901967827361 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 5/789 24/18639 0.208333333333333 4.92157794676806 0.0029154968760458 0.0482382210400305 GO:0042379 chemokine receptor binding 9/789 72/18639 0.125 2.95294676806084 0.00326017525299976 0.0516892733977652 GO:0030695 GTPase regulator activity 34/789 489/18639 0.0695296523517382 1.64253889757167 0.00327282673830274 0.0516892733977652 GO:0005126 cytokine receptor binding 22/789 275/18639 0.08 1.88988593155894 0.0032944811616158 0.0516892733977652 GO:0060589 nucleoside-triphosphatase regulator activity 34/789 490/18639 0.0693877551020408 1.63918677737255 0.0033791495711107 0.0521190866052668 GO:0019865 immunoglobulin binding 5/789 26/18639 0.192307692307692 4.5429950277859 0.00420757744609292 0.063814924599076 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 4/789 17/18639 0.235294117647059 5.55848803399687 0.00487747216087967 0.0715887042967823 GO:0030169 low-density lipoprotein particle binding 4/789 17/18639 0.235294117647059 5.55848803399687 0.00487747216087967 0.0715887042967823 GO:0023026 MHC class II protein complex binding 5/789 27/18639 0.185185185185185 4.37473595268272 0.00498687178524076 0.0720325924534777 GO:0002020 protease binding 13/789 136/18639 0.0955882352941176 2.25813576381123 0.00511913844155762 0.0727877497158974 GO:0051537 2 iron, 2 sulfur cluster binding 5/789 28/18639 0.178571428571429 4.21849538294405 0.00586316012169233 0.0820842417036927 GO:0003746 translation elongation factor activity 4/789 18/18639 0.222222222222222 5.24968314321926 0.00606375706283359 0.0823584914504264 GO:0035615 clathrin adaptor activity 4/789 18/18639 0.222222222222222 5.24968314321926 0.00606375706283359 0.0823584914504264 GO:0033612 receptor serine/threonine kinase binding 5/789 30/18639 0.166666666666667 3.93726235741445 0.00793052766055041 0.104803095892107 GO:0001664 G protein-coupled receptor binding 22/789 297/18639 0.0740740740740741 1.74989438107309 0.00804946326637112 0.104803095892107 GO:0048487 beta-tubulin binding 6/789 42/18639 0.142857142857143 3.37479630635524 0.00806177660708516 0.104803095892107 GO:0019955 cytokine binding 13/789 144/18639 0.0902777777777778 2.13268377693283 0.00819932001861514 0.105089876294926 GO:0008200 ion channel inhibitor activity 6/789 43/18639 0.13953488372093 3.29631267132372 0.00904178437556662 0.113159684290171 GO:0070325 lipoprotein particle receptor binding 5/789 31/18639 0.161290322580645 3.81025389427205 0.00913313071860102 0.113159684290171 GO:0005085 guanyl-nucleotide exchange factor activity 18/789 230/18639 0.0782608695652174 1.84880145478592 0.00920199630491499 0.113159684290171 GO:0001851 complement component C3b binding 3/789 11/18639 0.272727272727273 6.44279294849637 0.00966155331295675 0.115623754182263 GO:0050786 RAGE receptor binding 3/789 11/18639 0.272727272727273 6.44279294849637 0.00966155331295675 0.115623754182263 GO:0140297 DNA-binding transcription factor binding 32/789 488/18639 0.0655737704918033 1.54908682914667 0.00978354843080691 0.115623754182263 GO:0016248 channel inhibitor activity 6/789 44/18639 0.136363636363636 3.22139647424819 0.0101040470160019 0.117465520618544 GO:0043425 bHLH transcription factor binding 5/789 32/18639 0.15625 3.69118346007605 0.0104557221649473 0.117465520618544 GO:0071813 lipoprotein particle binding 5/789 32/18639 0.15625 3.69118346007605 0.0104557221649473 0.117465520618544 GO:0071814 protein-lipid complex binding 5/789 32/18639 0.15625 3.69118346007605 0.0104557221649473 0.117465520618544 GO:0001846 opsonin binding 4/789 21/18639 0.19047619047619 4.49972840847366 0.0107259090057328 0.117597315605022 GO:0140312 cargo adaptor activity 4/789 21/18639 0.19047619047619 4.49972840847366 0.0107259090057328 0.117597315605022 GO:0005125 cytokine activity 18/789 234/18639 0.0769230769230769 1.81719801111436 0.0108736537617866 0.117797915752688 GO:0141110 transporter inhibitor activity 6/789 45/18639 0.133333333333333 3.14980988593156 0.0112520327230268 0.120462938564169 GO:0019956 chemokine binding 5/789 33/18639 0.151515151515152 3.57932941583132 0.0119035672830352 0.12595635148328 GO:0004032 aldose reductase (NADPH) activity 3/789 12/18639 0.25 5.90589353612167 0.0124817242736199 0.126789143240566 GO:0097371 MDM2/MDM4 family protein binding 3/789 12/18639 0.25 5.90589353612167 0.0124817242736199 0.126789143240566 GO:0030276 clathrin binding 6/789 46/18639 0.130434782608696 3.08133575797652 0.012489131792958 0.126789143240566 GO:0030021 extracellular matrix structural constituent conferring compression resistance 4/789 22/18639 0.181818181818182 4.29519529899758 0.0126789143240566 0.126789143240566 GO:0061133 endopeptidase activator activity 4/789 22/18639 0.181818181818182 4.29519529899758 0.0126789143240566 0.126789143240566 GO:0044325 transmembrane transporter binding 12/789 136/18639 0.0882352941176471 2.08443301274883 0.0128404682638033 0.12700897956588 GO:0005158 insulin receptor binding 4/789 23/18639 0.173913043478261 4.10844767730203 0.0148449363197982 0.145256903774369 GO:0035673 oligopeptide transmembrane transporter activity 3/789 13/18639 0.230769230769231 5.45159403334308 0.0157231267609248 0.15221324843023 GO:0005540 hyaluronic acid binding 4/789 24/18639 0.166666666666667 3.93726235741445 0.0172308242085486 0.165053158208203 GO:0048020 CCR chemokine receptor binding 6/789 50/18639 0.12 2.8348288973384 0.0183931490624136 0.174351725487462 GO:0023023 MHC protein complex binding 5/789 37/18639 0.135135135135135 3.19237488439009 0.0190440513372124 0.178251729397244 GO:0005161 platelet-derived growth factor receptor binding 3/789 14/18639 0.214285714285714 5.06219445953286 0.0193922211102497 0.178251729397244 GO:0032036 myosin heavy chain binding 3/789 14/18639 0.214285714285714 5.06219445953286 0.0193922211102497 0.178251729397244 GO:0001848 complement binding 4/789 25/18639 0.16 3.77977186311787 0.0198425662633537 0.178779557422295 GO:0120020 cholesterol transfer activity 4/789 25/18639 0.16 3.77977186311787 0.0198425662633537 0.178779557422295 GO:0001618 virus receptor activity 8/789 81/18639 0.0987654320987654 2.33319250809745 0.02112460806179 0.188464640551264 GO:0140272 exogenous protein binding 8/789 82/18639 0.0975609756097561 2.30473894092553 0.0225722059848619 0.196605859691416 GO:0008198 ferrous iron binding 4/789 26/18639 0.153846153846154 3.63439602222872 0.0226852915028556 0.196605859691416 GO:0050750 low-density lipoprotein particle receptor binding 4/789 26/18639 0.153846153846154 3.63439602222872 0.0226852915028556 0.196605859691416 GO:0005041 low-density lipoprotein particle receptor activity 3/789 15/18639 0.2 4.72471482889734 0.0234921836935448 0.199793337954447 GO:0005523 tropomyosin binding 3/789 15/18639 0.2 4.72471482889734 0.0234921836935448 0.199793337954447 GO:0016860 intramolecular oxidoreductase activity 6/789 53/18639 0.113207547169811 2.67436688428151 0.0239076773002094 0.200084834648489 GO:0019887 protein kinase regulator activity 18/789 255/18639 0.0705882352941176 1.66754641019906 0.023966205468885 0.200084834648489 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 23/789 349/18639 0.0659025787965616 1.55685445651345 0.0244241216785373 0.202054097522445 GO:0004860 protein kinase inhibitor activity 8/789 84/18639 0.0952380952380952 2.24986420423683 0.0256743512283962 0.210483419980545 GO:0017070 U6 snRNA binding 3/789 16/18639 0.1875 4.42942015209125 0.0280232560419303 0.227688955340684 GO:0001530 lipopolysaccharide binding 5/789 41/18639 0.121951219512195 2.88092367615691 0.0285407782290069 0.229841665384038 GO:0019838 growth factor binding 11/789 136/18639 0.0808823529411765 1.91073026168642 0.0297291007486312 0.237311242818021 GO:0042056 chemoattractant activity 5/789 42/18639 0.119047619047619 2.81233025529603 0.0313082108806179 0.247743233924889 GO:0008429 phosphatidylethanolamine binding 3/789 17/18639 0.176470588235294 4.16886602549765 0.032983066873584 0.258746472887598 GO:0140375 immune receptor activity 12/789 156/18639 0.0769230769230769 1.81719801111436 0.0334895077852729 0.260473949441012 GO:0048156 tau protein binding 5/789 43/18639 0.116279069767442 2.7469272261031 0.0342380038418088 0.264038843186831 GO:0043539 protein serine/threonine kinase activator activity 7/789 73/18639 0.0958904109589041 2.26527423303297 0.034535893564229 0.26409800960881 GO:0019210 kinase inhibitor activity 8/789 90/18639 0.0888888888888889 2.09987325728771 0.0367347431805483 0.276440538765643 GO:0019207 kinase regulator activity 19/789 287/18639 0.0662020905923345 1.56392999562804 0.0367574782314756 0.276440538765643 GO:0030228 lipoprotein particle receptor activity 3/789 18/18639 0.166666666666667 3.93726235741445 0.0383669288357341 0.281563751939661 GO:0070064 proline-rich region binding 3/789 18/18639 0.166666666666667 3.93726235741445 0.0383669288357341 0.281563751939661 GO:1990381 ubiquitin-specific protease binding 3/789 18/18639 0.166666666666667 3.93726235741445 0.0383669288357341 0.281563751939661 GO:0020037 heme binding 11/789 142/18639 0.0774647887323944 1.82999518020672 0.0389246540519045 0.283371481497865 GO:0051536 iron-sulfur cluster binding 7/789 76/18639 0.0921052631578947 2.17585551330798 0.0416456551036778 0.300774175748784 GO:0051219 phosphoprotein binding 8/789 93/18639 0.0860215053763441 2.03213541027843 0.04331099954004 0.310338658121547 GO:0015026 coreceptor activity 6/789 61/18639 0.0983606557377049 2.32363024372 0.0436962828104657 0.310653260605655 GO:0051540 metal cluster binding 7/789 77/18639 0.0909090909090909 2.14759764949879 0.0442113595719344 0.311878583026824 GO:0120015 sterol transfer activity 4/789 32/18639 0.125 2.95294676806084 0.0447742624353454 0.313419837047418 GO:0005200 structural constituent of cytoskeleton 9/789 112/18639 0.0803571428571429 1.89832292232482 0.0481005938621753 0.3341338962945 GO:0016874 ligase activity 12/789 167/18639 0.0718562874251497 1.69750233373557 0.0517732141974593 0.356921400906727 GO:0048306 calcium-dependent protein binding 7/789 80/18639 0.0875 2.06706273764259 0.052509386675841 0.357096786949444 GO:0005539 glycosaminoglycan binding 16/789 242/18639 0.0661157024793388 1.56188919963548 0.0525834829134346 0.357096786949444 GO:0016247 channel regulator activity 12/789 168/18639 0.0714285714285714 1.68739815317762 0.0537159357683298 0.362085196660593 GO:0005123 death receptor binding 3/789 21/18639 0.142857142857143 3.37479630635524 0.0569867907061817 0.375782460453807 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 3/789 21/18639 0.142857142857143 3.37479630635524 0.0569867907061817 0.375782460453807 GO:0072542 protein phosphatase activator activity 3/789 21/18639 0.142857142857143 3.37479630635524 0.0569867907061817 0.375782460453807 GO:0141108 transporter regulator activity 12/789 170/18639 0.0705882352941176 1.66754641019906 0.0577477454441197 0.378060779526251 GO:0046906 tetrapyrrole binding 11/789 152/18639 0.0723684210526316 1.70960076045627 0.058344331915045 0.379238157447792 GO:0033218 amide binding 16/789 247/18639 0.0647773279352227 1.53027200935946 0.0609520555310517 0.391546517365856 GO:0003743 translation initiation factor activity 5/789 51/18639 0.0980392156862745 2.31603668083203 0.0636845257893377 0.391546517365856 GO:0050840 extracellular matrix binding 6/789 67/18639 0.0895522388059701 2.11554395323761 0.0637608125441202 0.391546517365856 GO:0005381 iron ion transmembrane transporter activity 2/789 10/18639 0.2 4.72471482889734 0.0642771594001805 0.391546517365856 GO:0008239 dipeptidyl-peptidase activity 2/789 10/18639 0.2 4.72471482889734 0.0642771594001805 0.391546517365856 GO:0016175 superoxide-generating NAD(P)H oxidase activity 2/789 10/18639 0.2 4.72471482889734 0.0642771594001805 0.391546517365856 GO:0043422 protein kinase B binding 2/789 10/18639 0.2 4.72471482889734 0.0642771594001805 0.391546517365856 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 2/789 10/18639 0.2 4.72471482889734 0.0642771594001805 0.391546517365856 GO:1905394 retromer complex binding 2/789 10/18639 0.2 4.72471482889734 0.0642771594001805 0.391546517365856 GO:0042277 peptide binding 16/789 249/18639 0.0642570281124498 1.51798066791882 0.0645406347306356 0.391546517365856 GO:0005096 GTPase activator activity 17/789 271/18639 0.0627306273062731 1.4819216252999 0.0692974434412167 0.417620354513293 GO:0030295 protein kinase activator activity 10/789 139/18639 0.0719424460431655 1.69953770823645 0.071059983745741 0.425424902688318 GO:0008199 ferric iron binding 2/789 11/18639 0.181818181818182 4.29519529899758 0.076413960752897 0.440105723323647 GO:0010854 adenylate cyclase regulator activity 2/789 11/18639 0.181818181818182 4.29519529899758 0.076413960752897 0.440105723323647 GO:0015217 ADP transmembrane transporter activity 2/789 11/18639 0.181818181818182 4.29519529899758 0.076413960752897 0.440105723323647 GO:0032050 clathrin heavy chain binding 2/789 11/18639 0.181818181818182 4.29519529899758 0.076413960752897 0.440105723323647 GO:0034713 type I transforming growth factor beta receptor binding 2/789 11/18639 0.181818181818182 4.29519529899758 0.076413960752897 0.440105723323647 GO:0140031 phosphorylation-dependent protein binding 2/789 11/18639 0.181818181818182 4.29519529899758 0.076413960752897 0.440105723323647 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 5/789 54/18639 0.0925925925925926 2.18736797634136 0.0775006659610949 0.441518878081802 GO:0001091 RNA polymerase II general transcription initiation factor binding 3/789 24/18639 0.125 2.95294676806084 0.0790852495904766 0.441518878081802 GO:0042625 ATPase-coupled ion transmembrane transporter activity 3/789 24/18639 0.125 2.95294676806084 0.0790852495904766 0.441518878081802 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 3/789 24/18639 0.125 2.95294676806084 0.0790852495904766 0.441518878081802 GO:0046961 proton-transporting ATPase activity, rotational mechanism 3/789 24/18639 0.125 2.95294676806084 0.0790852495904766 0.441518878081802 GO:0016776 phosphotransferase activity, phosphate group as acceptor 4/789 39/18639 0.102564102564103 2.42293068148581 0.0815318101140903 0.452402117096477 GO:0019211 phosphatase activator activity 3/789 25/18639 0.12 2.8348288973384 0.0871637973169026 0.458600967934264 GO:0004875 complement receptor activity 2/789 12/18639 0.166666666666667 3.93726235741445 0.0892004080487524 0.458600967934264 GO:0005095 GTPase inhibitor activity 2/789 12/18639 0.166666666666667 3.93726235741445 0.0892004080487524 0.458600967934264 GO:0008179 adenylate cyclase binding 2/789 12/18639 0.166666666666667 3.93726235741445 0.0892004080487524 0.458600967934264 GO:0010853 cyclase activator activity 2/789 12/18639 0.166666666666667 3.93726235741445 0.0892004080487524 0.458600967934264 GO:0016208 AMP binding 2/789 12/18639 0.166666666666667 3.93726235741445 0.0892004080487524 0.458600967934264 GO:0016801 hydrolase activity, acting on ether bonds 2/789 12/18639 0.166666666666667 3.93726235741445 0.0892004080487524 0.458600967934264 GO:0016803 ether hydrolase activity 2/789 12/18639 0.166666666666667 3.93726235741445 0.0892004080487524 0.458600967934264 GO:0035259 nuclear glucocorticoid receptor binding 2/789 12/18639 0.166666666666667 3.93726235741445 0.0892004080487524 0.458600967934264 GO:0035497 cAMP response element binding 2/789 12/18639 0.166666666666667 3.93726235741445 0.0892004080487524 0.458600967934264 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 2/789 12/18639 0.166666666666667 3.93726235741445 0.0892004080487524 0.458600967934264 GO:0070008 serine-type exopeptidase activity 2/789 12/18639 0.166666666666667 3.93726235741445 0.0892004080487524 0.458600967934264 GO:1990459 transferrin receptor binding 2/789 12/18639 0.166666666666667 3.93726235741445 0.0892004080487524 0.458600967934264 GO:0061135 endopeptidase regulator activity 12/789 184/18639 0.0652173913043478 1.54066787898826 0.0916145158920408 0.46836634529077 GO:0042169 SH2 domain binding 4/789 41/18639 0.0975609756097561 2.30473894092553 0.0941060170247548 0.470120939768536 GO:0042287 MHC protein binding 4/789 41/18639 0.0975609756097561 2.30473894092553 0.0941060170247548 0.470120939768536 GO:0140318 protein transporter activity 4/789 41/18639 0.0975609756097561 2.30473894092553 0.0941060170247548 0.470120939768536 GO:0005160 transforming growth factor beta receptor binding 3/789 26/18639 0.115384615384615 2.72579701667154 0.0955740372056913 0.470120939768536 GO:0030247 polysaccharide binding 3/789 26/18639 0.115384615384615 2.72579701667154 0.0955740372056913 0.470120939768536 GO:0043548 phosphatidylinositol 3-kinase binding 3/789 26/18639 0.115384615384615 2.72579701667154 0.0955740372056913 0.470120939768536 GO:0050681 nuclear androgen receptor binding 3/789 26/18639 0.115384615384615 2.72579701667154 0.0955740372056913 0.470120939768536 GO:0019209 kinase activator activity 10/789 148/18639 0.0675675675675676 1.59618744219505 0.0978935881437661 0.478941748445307 GO:0019894 kinesin binding 4/789 42/18639 0.0952380952380952 2.24986420423683 0.100716312408348 0.490116814393566 GO:0008035 high-density lipoprotein particle binding 2/789 13/18639 0.153846153846154 3.63439602222872 0.102559913737448 0.49120800790041 GO:0019855 calcium channel inhibitor activity 2/789 13/18639 0.153846153846154 3.63439602222872 0.102559913737448 0.49120800790041 GO:0031432 titin binding 2/789 13/18639 0.153846153846154 3.63439602222872 0.102559913737448 0.49120800790041 GO:0008320 protein transmembrane transporter activity 3/789 27/18639 0.111111111111111 2.62484157160963 0.104300382163815 0.49692852235116 GO:0003924 GTPase activity 19/789 331/18639 0.0574018126888218 1.35603597808232 0.111196360122409 0.527024415163503 GO:0019789 SUMO transferase activity 3/789 28/18639 0.107142857142857 2.53109722976643 0.113326832370208 0.527081035901508 GO:0046875 ephrin receptor binding 3/789 28/18639 0.107142857142857 2.53109722976643 0.113326832370208 0.527081035901508 GO:0097718 disordered domain specific binding 3/789 28/18639 0.107142857142857 2.53109722976643 0.113326832370208 0.527081035901508 GO:0019205 nucleobase-containing compound kinase activity 4/789 44/18639 0.0909090909090909 2.14759764949879 0.114554850426024 0.527081035901508 GO:0051087 protein-folding chaperone binding 9/789 134/18639 0.0671641791044776 1.58665796492821 0.115428060310406 0.527081035901508 GO:0005347 ATP transmembrane transporter activity 2/789 14/18639 0.142857142857143 3.37479630635524 0.116421195841981 0.527081035901508 GO:0016530 metallochaperone activity 2/789 14/18639 0.142857142857143 3.37479630635524 0.116421195841981 0.527081035901508 GO:0034236 protein kinase A catalytic subunit binding 2/789 14/18639 0.142857142857143 3.37479630635524 0.116421195841981 0.527081035901508 GO:0061665 SUMO ligase activity 2/789 14/18639 0.142857142857143 3.37479630635524 0.116421195841981 0.527081035901508 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 3/789 29/18639 0.103448275862069 2.4438180149469 0.122637085814224 0.552474000450217 GO:0005507 copper ion binding 5/789 63/18639 0.0793650793650794 1.87488683686402 0.127577510229496 0.571891105370116 GO:0003779 actin binding 24/789 443/18639 0.054176072234763 1.27983245929499 0.129913580765829 0.571891105370116 GO:0016846 carbon-sulfur lyase activity 2/789 15/18639 0.133333333333333 3.14980988593156 0.130717966941741 0.571891105370116 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 2/789 15/18639 0.133333333333333 3.14980988593156 0.130717966941741 0.571891105370116 GO:0050700 CARD domain binding 2/789 15/18639 0.133333333333333 3.14980988593156 0.130717966941741 0.571891105370116 GO:0050780 dopamine receptor binding 2/789 15/18639 0.133333333333333 3.14980988593156 0.130717966941741 0.571891105370116 GO:0001965 G-protein alpha-subunit binding 3/789 30/18639 0.1 2.36235741444867 0.132214638233668 0.57293009901256 GO:0008106 alcohol dehydrogenase (NADP+) activity 3/789 30/18639 0.1 2.36235741444867 0.132214638233668 0.57293009901256 GO:0043495 protein-membrane adaptor activity 4/789 47/18639 0.0851063829787234 2.01051694846695 0.136762695746581 0.589829635684307 GO:0003697 single-stranded DNA binding 8/789 121/18639 0.0661157024793388 1.56188919963548 0.141248538256062 0.600539752783448 GO:0051082 unfolded protein binding 8/789 121/18639 0.0661157024793388 1.56188919963548 0.141248538256062 0.600539752783448 GO:0099106 ion channel regulator activity 10/789 160/18639 0.0625 1.47647338403042 0.141723657219874 0.600539752783448 GO:0017147 Wnt-protein binding 3/789 31/18639 0.0967741935483871 2.28615233656323 0.142042873233538 0.600539752783448 GO:0016853 isomerase activity 11/789 180/18639 0.0611111111111111 1.4436628643853 0.142545699561786 0.600539752783448 GO:0034450 ubiquitin-ubiquitin ligase activity 2/789 16/18639 0.125 2.95294676806084 0.145388639927428 0.606897533642016 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/789 16/18639 0.125 2.95294676806084 0.145388639927428 0.606897533642016 GO:0022884 macromolecule transmembrane transporter activity 3/789 32/18639 0.09375 2.21471007604563 0.15210514331611 0.630609055895908 GO:0060590 ATPase regulator activity 4/789 49/18639 0.0816326530612245 1.928455032203 0.152454936590219 0.630609055895908 GO:0003714 transcription corepressor activity 12/789 204/18639 0.0588235294117647 1.38962200849922 0.157369385730966 0.647991588303976 GO:0004550 nucleoside diphosphate kinase activity 2/789 17/18639 0.117647058823529 2.77924401699843 0.160376049667941 0.648632023101449 GO:0015278 intracellularly gated calcium channel activity 2/789 17/18639 0.117647058823529 2.77924401699843 0.160376049667941 0.648632023101449 GO:0032977 membrane insertase activity 2/789 17/18639 0.117647058823529 2.77924401699843 0.160376049667941 0.648632023101449 GO:0046965 nuclear retinoid X receptor binding 2/789 17/18639 0.117647058823529 2.77924401699843 0.160376049667941 0.648632023101449 GO:0140311 protein sequestering activity 3/789 33/18639 0.0909090909090909 2.14759764949879 0.162384842505534 0.653032694342605 GO:0008081 phosphoric diester hydrolase activity 6/789 87/18639 0.0689655172413793 1.6292120099646 0.162899364412936 0.653032694342605 GO:0042826 histone deacetylase binding 8/789 127/18639 0.062992125984252 1.48809915870782 0.17055217680355 0.680712635487853 GO:0097110 scaffold protein binding 5/789 70/18639 0.0714285714285714 1.68739815317762 0.174456654511439 0.688882511605558 GO:0000400 four-way junction DNA binding 2/789 18/18639 0.111111111111111 2.62484157160963 0.175627189771966 0.688882511605558 GO:0000900 mRNA regulatory element binding translation repressor activity 2/789 18/18639 0.111111111111111 2.62484157160963 0.175627189771966 0.688882511605558 GO:0050811 GABA receptor binding 2/789 18/18639 0.111111111111111 2.62484157160963 0.175627189771966 0.688882511605558 GO:0051015 actin filament binding 12/789 209/18639 0.0574162679425837 1.35637746284134 0.176843322369397 0.690675636721678 GO:0030414 peptidase inhibitor activity 10/789 169/18639 0.0591715976331361 1.39784462393412 0.180257785003803 0.696696646401999 GO:0005154 epidermal growth factor receptor binding 3/789 35/18639 0.0857142857142857 2.02487778381315 0.183530693886478 0.696696646401999 GO:0140296 general transcription initiation factor binding 4/789 53/18639 0.0754716981132075 1.78291125618767 0.185704189369832 0.696696646401999 GO:0005518 collagen binding 5/789 72/18639 0.0694444444444444 1.64052598225602 0.188920878709816 0.696696646401999 GO:1901681 sulfur compound binding 15/789 275/18639 0.0545454545454545 1.28855858969927 0.190611199256097 0.696696646401999 GO:0005346 purine ribonucleotide transmembrane transporter activity 2/789 19/18639 0.105263157894737 2.48669201520913 0.191092963667579 0.696696646401999 GO:0008301 DNA binding, bending 2/789 19/18639 0.105263157894737 2.48669201520913 0.191092963667579 0.696696646401999 GO:0043395 heparan sulfate proteoglycan binding 2/789 19/18639 0.105263157894737 2.48669201520913 0.191092963667579 0.696696646401999 GO:0050145 nucleoside monophosphate kinase activity 2/789 19/18639 0.105263157894737 2.48669201520913 0.191092963667579 0.696696646401999 GO:0070003 threonine-type peptidase activity 2/789 19/18639 0.105263157894737 2.48669201520913 0.191092963667579 0.696696646401999 GO:0008201 heparin binding 10/789 172/18639 0.0581395348837209 1.37346361305155 0.194080930620422 0.696696646401999 GO:0003925 G protein activity 4/789 54/18639 0.0740740740740741 1.74989438107309 0.194360471242532 0.696696646401999 GO:0015485 cholesterol binding 4/789 54/18639 0.0740740740740741 1.74989438107309 0.194360471242532 0.696696646401999 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 4/789 54/18639 0.0740740740740741 1.74989438107309 0.194360471242532 0.696696646401999 GO:0017069 snRNA binding 4/789 54/18639 0.0740740740740741 1.74989438107309 0.194360471242532 0.696696646401999 GO:0004033 aldo-keto reductase (NADPH) activity 3/789 36/18639 0.0833333333333333 1.96863117870722 0.194364390159917 0.696696646401999 GO:0004869 cysteine-type endopeptidase inhibitor activity 3/789 36/18639 0.0833333333333333 1.96863117870722 0.194364390159917 0.696696646401999 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 3/789 36/18639 0.0833333333333333 1.96863117870722 0.194364390159917 0.696696646401999 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 3/789 36/18639 0.0833333333333333 1.96863117870722 0.194364390159917 0.696696646401999 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 3/789 36/18639 0.0833333333333333 1.96863117870722 0.194364390159917 0.696696646401999 GO:0043178 alcohol binding 6/789 92/18639 0.0652173913043478 1.54066787898826 0.194462580424294 0.696696646401999 GO:0140313 molecular sequestering activity 4/789 55/18639 0.0727272727272727 1.71807811959903 0.203138811497996 0.723547822415986 GO:0043394 proteoglycan binding 3/789 37/18639 0.0810810810810811 1.91542493063406 0.205350699759157 0.723547822415986 GO:0000339 RNA cap binding 2/789 20/18639 0.1 2.36235741444867 0.20672794926171 0.723547822415986 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 2/789 20/18639 0.1 2.36235741444867 0.20672794926171 0.723547822415986 GO:0010851 cyclase regulator activity 2/789 20/18639 0.1 2.36235741444867 0.20672794926171 0.723547822415986 GO:0016004 phospholipase activator activity 2/789 20/18639 0.1 2.36235741444867 0.20672794926171 0.723547822415986 GO:0044183 protein folding chaperone 5/789 75/18639 0.0666666666666667 1.57490494296578 0.211376824261444 0.736984329800438 GO:0005109 frizzled binding 3/789 38/18639 0.0789473684210526 1.86501901140684 0.216474061912755 0.74901671612398 GO:0042887 amide transmembrane transporter activity 3/789 38/18639 0.0789473684210526 1.86501901140684 0.216474061912755 0.74901671612398 GO:0017022 myosin binding 5/789 76/18639 0.0657894736842105 1.5541825095057 0.219046165132263 0.752196265171168 GO:0098631 cell adhesion mediator activity 5/789 76/18639 0.0657894736842105 1.5541825095057 0.219046165132263 0.752196265171168 GO:0009931 calcium-dependent protein serine/threonine kinase activity 2/789 21/18639 0.0952380952380952 2.24986420423683 0.222490176478081 0.761150603740805 GO:0016922 nuclear receptor binding 8/789 137/18639 0.0583941605839416 1.37947878215981 0.224764303589288 0.766050622720046 GO:0019208 phosphatase regulator activity 7/789 117/18639 0.0598290598290598 1.41337623086673 0.227089146795167 0.767498211488909 GO:0000217 DNA secondary structure binding 3/789 39/18639 0.0769230769230769 1.81719801111436 0.227719249562643 0.767498211488909 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 3/789 39/18639 0.0769230769230769 1.81719801111436 0.227719249562643 0.767498211488909 GO:0061980 regulatory RNA binding 4/789 58/18639 0.0689655172413793 1.6292120099646 0.230128119263306 0.772754939223649 GO:0042626 ATPase-coupled transmembrane transporter activity 6/789 98/18639 0.0612244897959184 1.44634127415225 0.2350487421878 0.775011467543647 GO:0008093 cytoskeletal anchor activity 2/789 22/18639 0.0909090909090909 2.14759764949879 0.238340917007133 0.775011467543647 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 2/789 22/18639 0.0909090909090909 2.14759764949879 0.238340917007133 0.775011467543647 GO:0031683 G-protein beta/gamma-subunit complex binding 2/789 22/18639 0.0909090909090909 2.14759764949879 0.238340917007133 0.775011467543647 GO:0034062 5'-3' RNA polymerase activity 2/789 22/18639 0.0909090909090909 2.14759764949879 0.238340917007133 0.775011467543647 GO:0097747 RNA polymerase activity 2/789 22/18639 0.0909090909090909 2.14759764949879 0.238340917007133 0.775011467543647 GO:0140517 protein-RNA adaptor activity 2/789 22/18639 0.0909090909090909 2.14759764949879 0.238340917007133 0.775011467543647 GO:0004177 aminopeptidase activity 3/789 40/18639 0.075 1.7717680608365 0.239071398849202 0.775011467543647 GO:0045309 protein phosphorylated amino acid binding 4/789 59/18639 0.0677966101694915 1.60159824708384 0.239316727889851 0.775011467543647 GO:0070888 E-box binding 4/789 59/18639 0.0677966101694915 1.60159824708384 0.239316727889851 0.775011467543647 GO:0046332 SMAD binding 5/789 79/18639 0.0632911392405063 1.49516292053713 0.24254019782173 0.782665177367993 GO:0008083 growth factor activity 9/789 162/18639 0.0555555555555556 1.31242078580482 0.248660684907277 0.799580294224813 GO:0000295 adenine nucleotide transmembrane transporter activity 2/789 23/18639 0.0869565217391304 2.05422383865102 0.254244485634694 0.803341951137402 GO:0004602 glutathione peroxidase activity 2/789 23/18639 0.0869565217391304 2.05422383865102 0.254244485634694 0.803341951137402 GO:0016493 C-C chemokine receptor activity 2/789 23/18639 0.0869565217391304 2.05422383865102 0.254244485634694 0.803341951137402 GO:0016849 phosphorus-oxygen lyase activity 2/789 23/18639 0.0869565217391304 2.05422383865102 0.254244485634694 0.803341951137402 GO:0017134 fibroblast growth factor binding 2/789 23/18639 0.0869565217391304 2.05422383865102 0.254244485634694 0.803341951137402 GO:0140104 molecular carrier activity 13/789 249/18639 0.0522088353413655 1.23335929268404 0.257816337037933 0.811809227351277 GO:0016859 cis-trans isomerase activity 3/789 42/18639 0.0714285714285714 1.68739815317762 0.262039089783168 0.819434954304751 GO:0035198 miRNA binding 3/789 42/18639 0.0714285714285714 1.68739815317762 0.262039089783168 0.819434954304751 GO:0008238 exopeptidase activity 6/789 102/18639 0.0588235294117647 1.38962200849922 0.263434745056079 0.820978143839152 GO:0005315 phosphate transmembrane transporter activity 2/789 24/18639 0.0833333333333333 1.96863117870722 0.270168052547805 0.830584215603049 GO:0015295 solute:proton symporter activity 2/789 24/18639 0.0833333333333333 1.96863117870722 0.270168052547805 0.830584215603049 GO:0019957 C-C chemokine binding 2/789 24/18639 0.0833333333333333 1.96863117870722 0.270168052547805 0.830584215603049 GO:0060229 lipase activator activity 2/789 24/18639 0.0833333333333333 1.96863117870722 0.270168052547805 0.830584215603049 GO:0005543 phospholipid binding 24/789 497/18639 0.0482897384305835 1.14077621623276 0.281508652323191 0.862033556629112 GO:0051117 ATPase binding 5/789 84/18639 0.0595238095238095 1.40616512764802 0.283031538396926 0.862033556629112 GO:0005537 D-mannose binding 2/789 25/18639 0.08 1.88988593155894 0.286081466046145 0.862033556629112 GO:0015662 P-type ion transporter activity 2/789 25/18639 0.08 1.88988593155894 0.286081466046145 0.862033556629112 GO:0042974 nuclear retinoic acid receptor binding 2/789 25/18639 0.08 1.88988593155894 0.286081466046145 0.862033556629112 GO:0140358 P-type transmembrane transporter activity 2/789 25/18639 0.08 1.88988593155894 0.286081466046145 0.862033556629112 GO:0120013 lipid transfer activity 4/789 65/18639 0.0615384615384615 1.45375840889149 0.295933005719081 0.875344864386379 GO:0004715 non-membrane spanning protein tyrosine kinase activity 3/789 45/18639 0.0666666666666667 1.57490494296578 0.296944605186904 0.875344864386379 GO:0001637 G protein-coupled chemoattractant receptor activity 2/789 26/18639 0.0769230769230769 1.81719801111436 0.301957085116183 0.875344864386379 GO:0004950 chemokine receptor activity 2/789 26/18639 0.0769230769230769 1.81719801111436 0.301957085116183 0.875344864386379 GO:0015216 purine nucleotide transmembrane transporter activity 2/789 26/18639 0.0769230769230769 1.81719801111436 0.301957085116183 0.875344864386379 GO:0070006 metalloaminopeptidase activity 2/789 26/18639 0.0769230769230769 1.81719801111436 0.301957085116183 0.875344864386379 GO:0097602 cullin family protein binding 2/789 26/18639 0.0769230769230769 1.81719801111436 0.301957085116183 0.875344864386379 GO:0004180 carboxypeptidase activity 3/789 46/18639 0.0652173913043478 1.54066787898826 0.308649417737319 0.875344864386379 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 4/789 67/18639 0.0597014925373134 1.41036263549174 0.315194585387576 0.875344864386379 GO:0004197 cysteine-type endopeptidase activity 5/789 88/18639 0.0568181818181818 1.34224853093674 0.316286272793573 0.875344864386379 GO:0035091 phosphatidylinositol binding 14/789 284/18639 0.0492957746478873 1.16454238740427 0.317650563858019 0.875344864386379 GO:0001671 ATPase activator activity 2/789 27/18639 0.0740740740740741 1.74989438107309 0.317769621352372 0.875344864386379 GO:0004364 glutathione transferase activity 2/789 27/18639 0.0740740740740741 1.74989438107309 0.317769621352372 0.875344864386379 GO:0001784 phosphotyrosine residue binding 3/789 47/18639 0.0638297872340425 1.50788771135021 0.320368966963961 0.875344864386379 GO:0005504 fatty acid binding 3/789 47/18639 0.0638297872340425 1.50788771135021 0.320368966963961 0.875344864386379 GO:0032934 sterol binding 4/789 68/18639 0.0588235294117647 1.38962200849922 0.324866765710263 0.875344864386379 GO:0005506 iron ion binding 8/789 154/18639 0.051948051948052 1.22719865685645 0.328119589745242 0.875344864386379 GO:0046625 sphingolipid binding 2/789 28/18639 0.0714285714285714 1.68739815317762 0.333495989735615 0.875344864386379 GO:0051959 dynein light intermediate chain binding 2/789 28/18639 0.0714285714285714 1.68739815317762 0.333495989735615 0.875344864386379 GO:0043021 ribonucleoprotein complex binding 9/789 177/18639 0.0508474576271186 1.20119868531288 0.335090860029546 0.875344864386379 GO:0043022 ribosome binding 6/789 112/18639 0.0535714285714286 1.26554861488322 0.337524635989595 0.875344864386379 GO:0016829 lyase activity 10/789 200/18639 0.05 1.18117870722433 0.340683804717546 0.875344864386379 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 2/789 29/18639 0.0689655172413793 1.6292120099646 0.349115167803866 0.875344864386379 GO:0043236 laminin binding 2/789 29/18639 0.0689655172413793 1.6292120099646 0.349115167803866 0.875344864386379 GO:0051861 glycolipid binding 2/789 29/18639 0.0689655172413793 1.6292120099646 0.349115167803866 0.875344864386379 GO:0097472 cyclin-dependent protein kinase activity 2/789 29/18639 0.0689655172413793 1.6292120099646 0.349115167803866 0.875344864386379 GO:0099604 ligand-gated calcium channel activity 2/789 29/18639 0.0689655172413793 1.6292120099646 0.349115167803866 0.875344864386379 GO:0001094 TFIID-class transcription factor complex binding 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0003680 minor groove of adenine-thymine-rich DNA binding 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0004935 adrenergic receptor activity 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0005031 tumor necrosis factor receptor activity 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0005345 purine nucleobase transmembrane transporter activity 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0005528 FK506 binding 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0008140 cAMP response element binding protein binding 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0016868 intramolecular phosphotransferase activity 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0019911 structural constituent of myelin sheath 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0030957 Tat protein binding 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0033204 ribonuclease P RNA binding 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0043121 neurotrophin binding 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0043208 glycosphingolipid binding 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0047429 nucleoside triphosphate diphosphatase activity 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0050815 phosphoserine residue binding 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0051880 G-quadruplex DNA binding 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0070097 delta-catenin binding 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0070513 death domain binding 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0098505 G-rich strand telomeric DNA binding 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0141109 transporter activator activity 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/789 10/18639 0.1 2.36235741444867 0.351201616760274 0.875344864386379 GO:0140299 molecular sensor activity 4/789 71/18639 0.0563380281690141 1.33090558560488 0.35396972347785 0.875344864386379 GO:0032813 tumor necrosis factor receptor superfamily binding 3/789 50/18639 0.06 1.4174144486692 0.355504928153624 0.875344864386379 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 2/789 30/18639 0.0666666666666667 1.57490494296578 0.364608062773166 0.875344864386379 GO:0015215 nucleotide transmembrane transporter activity 2/789 30/18639 0.0666666666666667 1.57490494296578 0.364608062773166 0.875344864386379 GO:0015631 tubulin binding 18/789 385/18639 0.0467532467532468 1.10447879117081 0.366416887944401 0.875344864386379 GO:0005021 vascular endothelial growth factor receptor activity 3/789 51/18639 0.0588235294117647 1.38962200849922 0.367174676539245 0.875344864386379 GO:0005048 signal sequence binding 3/789 51/18639 0.0588235294117647 1.38962200849922 0.367174676539245 0.875344864386379 GO:0005261 monoatomic cation channel activity 16/789 341/18639 0.0469208211143695 1.1084374965155 0.372361875813514 0.875344864386379 GO:0004866 endopeptidase inhibitor activity 8/789 161/18639 0.0496894409937888 1.17384219351487 0.373002036823542 0.875344864386379 GO:0004521 RNA endonuclease activity 4/789 73/18639 0.0547945205479452 1.29444241887598 0.373381027985813 0.875344864386379 GO:0070851 growth factor receptor binding 7/789 139/18639 0.0503597122302158 1.18967639576552 0.374533820904917 0.875344864386379 GO:0005114 type II transforming growth factor beta receptor binding 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.875344864386379 GO:0005225 volume-sensitive anion channel activity 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.875344864386379 GO:0008172 S-methyltransferase activity 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.875344864386379 GO:0008271 secondary active sulfate transmembrane transporter activity 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.875344864386379 GO:0008503 benzodiazepine receptor activity 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.875344864386379 GO:0008526 phosphatidylinositol transfer activity 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.875344864386379 GO:0015173 aromatic amino acid transmembrane transporter activity 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.875344864386379 GO:0015205 nucleobase transmembrane transporter activity 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.875344864386379 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.875344864386379 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.875344864386379 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.875344864386379 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.875344864386379 GO:0032794 GTPase activating protein binding 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.875344864386379 GO:0035252 UDP-xylosyltransferase activity 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.875344864386379 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.875344864386379 GO:0042285 xylosyltransferase activity 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.875344864386379 GO:0042608 T cell receptor binding 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.875344864386379 GO:0050998 nitric-oxide synthase binding 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.875344864386379 GO:0070697 activin receptor binding 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.875344864386379 GO:0070990 snRNP binding 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.875344864386379 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.875344864386379 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.875344864386379 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/789 11/18639 0.0909090909090909 2.14759764949879 0.378680382361012 0.875344864386379 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 3/789 52/18639 0.0576923076923077 1.36289850833577 0.378807140646879 0.875344864386379 GO:0005184 neuropeptide hormone activity 2/789 31/18639 0.0645161290322581 1.52410155770882 0.379957386189692 0.875344864386379 GO:0070273 phosphatidylinositol-4-phosphate binding 2/789 31/18639 0.0645161290322581 1.52410155770882 0.379957386189692 0.875344864386379 GO:0072349 modified amino acid transmembrane transporter activity 2/789 31/18639 0.0645161290322581 1.52410155770882 0.379957386189692 0.875344864386379 GO:0005246 calcium channel regulator activity 3/789 53/18639 0.0566037735849057 1.33718344214076 0.390393317723501 0.885930376760902 GO:0019003 GDP binding 4/789 75/18639 0.0533333333333333 1.25992395437262 0.39274452353008 0.885930376760902 GO:0160041 neuropeptide activity 2/789 32/18639 0.0625 1.47647338403042 0.395147535714598 0.885930376760902 GO:0000340 RNA 7-methylguanosine cap binding 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.885930376760902 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.885930376760902 GO:0004526 ribonuclease P activity 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.885930376760902 GO:0005165 neurotrophin receptor binding 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.885930376760902 GO:0005527 macrolide binding 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.885930376760902 GO:0008603 cAMP-dependent protein kinase regulator activity 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.885930376760902 GO:0015132 prostaglandin transmembrane transporter activity 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.885930376760902 GO:0017166 vinculin binding 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.885930376760902 GO:0034452 dynactin binding 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.885930376760902 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.885930376760902 GO:0035197 siRNA binding 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.885930376760902 GO:0043047 single-stranded telomeric DNA binding 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.885930376760902 GO:0045295 gamma-catenin binding 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.885930376760902 GO:0070679 inositol 1,4,5 trisphosphate binding 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.885930376760902 GO:0097677 STAT family protein binding 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.885930376760902 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.885930376760902 GO:0140900 chloride:bicarbonate antiporter activity 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.885930376760902 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/789 12/18639 0.0833333333333333 1.96863117870722 0.404996743662127 0.885930376760902 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2/789 33/18639 0.0606060606060606 1.43173176633253 0.41016448366357 0.895083165788605 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 6/789 122/18639 0.0491803278688525 1.16181512186 0.413522322471386 0.900251946050146 GO:0015035 protein-disulfide reductase activity 2/789 34/18639 0.0588235294117647 1.38962200849922 0.424995671942199 0.902031865595599 GO:0030332 cyclin binding 2/789 34/18639 0.0588235294117647 1.38962200849922 0.424995671942199 0.902031865595599 GO:0019001 guanyl nucleotide binding 18/789 400/18639 0.045 1.0630608365019 0.429173689915526 0.902031865595599 GO:0032561 guanyl ribonucleotide binding 18/789 400/18639 0.045 1.0630608365019 0.429173689915526 0.902031865595599 GO:0005035 death receptor activity 1/789 13/18639 0.0769230769230769 1.81719801111436 0.430199812822517 0.902031865595599 GO:0005172 vascular endothelial growth factor receptor binding 1/789 13/18639 0.0769230769230769 1.81719801111436 0.430199812822517 0.902031865595599 GO:0005542 folic acid binding 1/789 13/18639 0.0769230769230769 1.81719801111436 0.430199812822517 0.902031865595599 GO:0017154 semaphorin receptor activity 1/789 13/18639 0.0769230769230769 1.81719801111436 0.430199812822517 0.902031865595599 GO:0032396 inhibitory MHC class I receptor activity 1/789 13/18639 0.0769230769230769 1.81719801111436 0.430199812822517 0.902031865595599 GO:0039706 co-receptor binding 1/789 13/18639 0.0769230769230769 1.81719801111436 0.430199812822517 0.902031865595599 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/789 13/18639 0.0769230769230769 1.81719801111436 0.430199812822517 0.902031865595599 GO:0045159 myosin II binding 1/789 13/18639 0.0769230769230769 1.81719801111436 0.430199812822517 0.902031865595599 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/789 13/18639 0.0769230769230769 1.81719801111436 0.430199812822517 0.902031865595599 GO:0071714 icosanoid transmembrane transporter activity 1/789 13/18639 0.0769230769230769 1.81719801111436 0.430199812822517 0.902031865595599 GO:0071837 HMG box domain binding 1/789 13/18639 0.0769230769230769 1.81719801111436 0.430199812822517 0.902031865595599 GO:0089720 caspase binding 1/789 13/18639 0.0769230769230769 1.81719801111436 0.430199812822517 0.902031865595599 GO:0003712 transcription coregulator activity 22/789 495/18639 0.0444444444444444 1.04993662864385 0.438081865785194 0.915476477947831 GO:0043015 gamma-tubulin binding 2/789 35/18639 0.0571428571428571 1.3499185225421 0.439629913036486 0.915476477947831 GO:0061631 ubiquitin conjugating enzyme activity 2/789 35/18639 0.0571428571428571 1.3499185225421 0.439629913036486 0.915476477947831 GO:0045505 dynein intermediate chain binding 2/789 36/18639 0.0555555555555556 1.31242078580482 0.454057296735107 0.924428821115491 GO:0008195 phosphatidate phosphatase activity 1/789 14/18639 0.0714285714285714 1.68739815317762 0.454336629513327 0.924428821115491 GO:0015386 potassium:proton antiporter activity 1/789 14/18639 0.0714285714285714 1.68739815317762 0.454336629513327 0.924428821115491 GO:0019992 diacylglycerol binding 1/789 14/18639 0.0714285714285714 1.68739815317762 0.454336629513327 0.924428821115491 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/789 14/18639 0.0714285714285714 1.68739815317762 0.454336629513327 0.924428821115491 GO:0031404 chloride ion binding 1/789 14/18639 0.0714285714285714 1.68739815317762 0.454336629513327 0.924428821115491 GO:0042813 Wnt receptor activity 1/789 14/18639 0.0714285714285714 1.68739815317762 0.454336629513327 0.924428821115491 GO:0044548 S100 protein binding 1/789 14/18639 0.0714285714285714 1.68739815317762 0.454336629513327 0.924428821115491 GO:0071933 Arp2/3 complex binding 1/789 14/18639 0.0714285714285714 1.68739815317762 0.454336629513327 0.924428821115491 GO:0098847 sequence-specific single stranded DNA binding 1/789 14/18639 0.0714285714285714 1.68739815317762 0.454336629513327 0.924428821115491 GO:0001786 phosphatidylserine binding 3/789 59/18639 0.0508474576271186 1.20119868531288 0.45849080413605 0.924428821115491 GO:0004879 nuclear receptor activity 3/789 59/18639 0.0508474576271186 1.20119868531288 0.45849080413605 0.924428821115491 GO:0036002 pre-mRNA binding 3/789 59/18639 0.0508474576271186 1.20119868531288 0.45849080413605 0.924428821115491 GO:0000149 SNARE binding 5/789 106/18639 0.0471698113207547 1.1143195351173 0.467677458817306 0.924428821115491 GO:0008013 beta-catenin binding 5/789 106/18639 0.0471698113207547 1.1143195351173 0.467677458817306 0.924428821115491 GO:0019213 deacetylase activity 2/789 37/18639 0.0540540540540541 1.27694995375604 0.46826910227659 0.924428821115491 GO:0022829 wide pore channel activity 2/789 37/18639 0.0540540540540541 1.27694995375604 0.46826910227659 0.924428821115491 GO:0001098 basal transcription machinery binding 3/789 60/18639 0.05 1.18117870722433 0.469538290150227 0.924428821115491 GO:0001099 basal RNA polymerase II transcription machinery binding 3/789 60/18639 0.05 1.18117870722433 0.469538290150227 0.924428821115491 GO:0004714 transmembrane receptor protein tyrosine kinase activity 3/789 60/18639 0.05 1.18117870722433 0.469538290150227 0.924428821115491 GO:0098531 ligand-modulated transcription factor activity 3/789 60/18639 0.05 1.18117870722433 0.469538290150227 0.924428821115491 GO:0016798 hydrolase activity, acting on glycosyl bonds 6/789 130/18639 0.0461538461538462 1.09031880666862 0.473732441751386 0.924428821115491 GO:0000774 adenyl-nucleotide exchange factor activity 1/789 15/18639 0.0666666666666667 1.57490494296578 0.47745224826844 0.924428821115491 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/789 15/18639 0.0666666666666667 1.57490494296578 0.47745224826844 0.924428821115491 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/789 15/18639 0.0666666666666667 1.57490494296578 0.47745224826844 0.924428821115491 GO:0004953 icosanoid receptor activity 1/789 15/18639 0.0666666666666667 1.57490494296578 0.47745224826844 0.924428821115491 GO:0005402 carbohydrate:monoatomic cation symporter activity 1/789 15/18639 0.0666666666666667 1.57490494296578 0.47745224826844 0.924428821115491 GO:0015116 sulfate transmembrane transporter activity 1/789 15/18639 0.0666666666666667 1.57490494296578 0.47745224826844 0.924428821115491 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/789 15/18639 0.0666666666666667 1.57490494296578 0.47745224826844 0.924428821115491 GO:0017081 chloride channel regulator activity 1/789 15/18639 0.0666666666666667 1.57490494296578 0.47745224826844 0.924428821115491 GO:0140776 protein-containing complex destabilizing activity 1/789 15/18639 0.0666666666666667 1.57490494296578 0.47745224826844 0.924428821115491 GO:0141050 histone H3K deacetylase activity 1/789 15/18639 0.0666666666666667 1.57490494296578 0.47745224826844 0.924428821115491 GO:0141051 histone H4K deacetylase activity 1/789 15/18639 0.0666666666666667 1.57490494296578 0.47745224826844 0.924428821115491 GO:0019905 syntaxin binding 3/789 61/18639 0.0491803278688525 1.16181512186 0.480483234589737 0.92516128688815 GO:0043531 ADP binding 2/789 38/18639 0.0526315789473684 1.24334600760456 0.482257715630137 0.92516128688815 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 6/789 132/18639 0.0454545454545455 1.0737988247494 0.488533765024741 0.92516128688815 GO:0015179 L-amino acid transmembrane transporter activity 3/789 62/18639 0.0483870967741935 1.14307616828161 0.491320437276651 0.92516128688815 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 2/789 39/18639 0.0512820512820513 1.21146534074291 0.496016551633785 0.92516128688815 GO:0046982 protein heterodimerization activity 16/789 369/18639 0.043360433604336 1.02432841818913 0.497107508114145 0.92516128688815 GO:0000062 fatty-acyl-CoA binding 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.92516128688815 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.92516128688815 GO:0005159 insulin-like growth factor receptor binding 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.92516128688815 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.92516128688815 GO:0015385 sodium:proton antiporter activity 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.92516128688815 GO:0015562 efflux transmembrane transporter activity 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.92516128688815 GO:0015923 mannosidase activity 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.92516128688815 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.92516128688815 GO:0016722 oxidoreductase activity, acting on metal ions 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.92516128688815 GO:0030275 LRR domain binding 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.92516128688815 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.92516128688815 GO:0070411 I-SMAD binding 1/789 16/18639 0.0625 1.47647338403042 0.499589822157841 0.92516128688815 GO:1901682 sulfur compound transmembrane transporter activity 3/789 63/18639 0.0476190476190476 1.12493210211841 0.502045069641206 0.92516128688815 GO:0015036 disulfide oxidoreductase activity 2/789 40/18639 0.05 1.18117870722433 0.50953998072771 0.92516128688815 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 2/789 40/18639 0.05 1.18117870722433 0.50953998072771 0.92516128688815 GO:0071855 neuropeptide receptor binding 2/789 40/18639 0.05 1.18117870722433 0.50953998072771 0.92516128688815 GO:0004029 aldehyde dehydrogenase (NAD+) activity 1/789 17/18639 0.0588235294117647 1.38962200849922 0.52079068293846 0.92516128688815 GO:0004549 tRNA-specific ribonuclease activity 1/789 17/18639 0.0588235294117647 1.38962200849922 0.52079068293846 0.92516128688815 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/789 17/18639 0.0588235294117647 1.38962200849922 0.52079068293846 0.92516128688815 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 1/789 17/18639 0.0588235294117647 1.38962200849922 0.52079068293846 0.92516128688815 GO:0005092 GDP-dissociation inhibitor activity 1/789 17/18639 0.0588235294117647 1.38962200849922 0.52079068293846 0.92516128688815 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/789 17/18639 0.0588235294117647 1.38962200849922 0.52079068293846 0.92516128688815 GO:0019198 transmembrane receptor protein phosphatase activity 1/789 17/18639 0.0588235294117647 1.38962200849922 0.52079068293846 0.92516128688815 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/789 17/18639 0.0588235294117647 1.38962200849922 0.52079068293846 0.92516128688815 GO:0031489 myosin V binding 1/789 17/18639 0.0588235294117647 1.38962200849922 0.52079068293846 0.92516128688815 GO:0036041 long-chain fatty acid binding 1/789 17/18639 0.0588235294117647 1.38962200849922 0.52079068293846 0.92516128688815 GO:0045125 bioactive lipid receptor activity 1/789 17/18639 0.0588235294117647 1.38962200849922 0.52079068293846 0.92516128688815 GO:0048038 quinone binding 1/789 17/18639 0.0588235294117647 1.38962200849922 0.52079068293846 0.92516128688815 GO:0070492 oligosaccharide binding 1/789 17/18639 0.0588235294117647 1.38962200849922 0.52079068293846 0.92516128688815 GO:1901567 fatty acid derivative binding 1/789 17/18639 0.0588235294117647 1.38962200849922 0.52079068293846 0.92516128688815 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 2/789 41/18639 0.0487804878048781 1.15236947046277 0.522823260033932 0.92516128688815 GO:0008227 G protein-coupled amine receptor activity 2/789 41/18639 0.0487804878048781 1.15236947046277 0.522823260033932 0.92516128688815 GO:0017080 sodium channel regulator activity 2/789 41/18639 0.0487804878048781 1.15236947046277 0.522823260033932 0.92516128688815 GO:0061650 ubiquitin-like protein conjugating enzyme activity 2/789 41/18639 0.0487804878048781 1.15236947046277 0.522823260033932 0.92516128688815 GO:0030246 carbohydrate binding 12/789 280/18639 0.0428571428571429 1.01243889190657 0.524304954142545 0.92516128688815 GO:1901981 phosphatidylinositol phosphate binding 8/789 185/18639 0.0432432432432432 1.02155996300483 0.526369420886172 0.92516128688815 GO:0031492 nucleosomal DNA binding 2/789 42/18639 0.0476190476190476 1.12493210211841 0.53586246854647 0.92516128688815 GO:0001221 transcription coregulator binding 5/789 115/18639 0.0434782608695652 1.02711191932551 0.539904182455626 0.92516128688815 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 1/789 18/18639 0.0555555555555556 1.31242078580482 0.541094417830606 0.92516128688815 GO:0004706 JUN kinase kinase kinase activity 1/789 18/18639 0.0555555555555556 1.31242078580482 0.541094417830606 0.92516128688815 GO:0008525 phosphatidylcholine transporter activity 1/789 18/18639 0.0555555555555556 1.31242078580482 0.541094417830606 0.92516128688815 GO:0015172 acidic amino acid transmembrane transporter activity 1/789 18/18639 0.0555555555555556 1.31242078580482 0.541094417830606 0.92516128688815 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 1/789 18/18639 0.0555555555555556 1.31242078580482 0.541094417830606 0.92516128688815 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/789 18/18639 0.0555555555555556 1.31242078580482 0.541094417830606 0.92516128688815 GO:0017075 syntaxin-1 binding 1/789 18/18639 0.0555555555555556 1.31242078580482 0.541094417830606 0.92516128688815 GO:0031690 adrenergic receptor binding 1/789 18/18639 0.0555555555555556 1.31242078580482 0.541094417830606 0.92516128688815 GO:0032393 MHC class I receptor activity 1/789 18/18639 0.0555555555555556 1.31242078580482 0.541094417830606 0.92516128688815 GO:0034185 apolipoprotein binding 1/789 18/18639 0.0555555555555556 1.31242078580482 0.541094417830606 0.92516128688815 GO:0070628 proteasome binding 1/789 18/18639 0.0555555555555556 1.31242078580482 0.541094417830606 0.92516128688815 GO:0098641 cadherin binding involved in cell-cell adhesion 1/789 18/18639 0.0555555555555556 1.31242078580482 0.541094417830606 0.92516128688815 GO:1901611 phosphatidylglycerol binding 1/789 18/18639 0.0555555555555556 1.31242078580482 0.541094417830606 0.92516128688815 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 4/789 91/18639 0.043956043956044 1.03839886349392 0.541255059576226 0.92516128688815 GO:0072341 modified amino acid binding 4/789 91/18639 0.043956043956044 1.03839886349392 0.541255059576226 0.92516128688815 GO:0016500 protein-hormone receptor activity 3/789 67/18639 0.0447761194029851 1.05777197661881 0.543733685836618 0.92516128688815 GO:0004713 protein tyrosine kinase activity 6/789 140/18639 0.0428571428571429 1.01243889190657 0.546225368506695 0.92516128688815 GO:0030145 manganese ion binding 3/789 68/18639 0.0441176470588235 1.04221650637441 0.553835235996295 0.92516128688815 GO:1990782 protein tyrosine kinase binding 5/789 117/18639 0.0427350427350427 1.00955445061909 0.555340087013737 0.92516128688815 GO:0019902 phosphatase binding 8/789 190/18639 0.0421052631578947 0.99467680608365 0.556866786806088 0.92516128688815 GO:0003756 protein disulfide isomerase activity 1/789 19/18639 0.0526315789473684 1.24334600760456 0.560538943061886 0.92516128688815 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/789 19/18639 0.0526315789473684 1.24334600760456 0.560538943061886 0.92516128688815 GO:0005229 intracellularly calcium-gated chloride channel activity 1/789 19/18639 0.0526315789473684 1.24334600760456 0.560538943061886 0.92516128688815 GO:0008574 plus-end-directed microtubule motor activity 1/789 19/18639 0.0526315789473684 1.24334600760456 0.560538943061886 0.92516128688815 GO:0015245 fatty acid transmembrane transporter activity 1/789 19/18639 0.0526315789473684 1.24334600760456 0.560538943061886 0.92516128688815 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 1/789 19/18639 0.0526315789473684 1.24334600760456 0.560538943061886 0.92516128688815 GO:0022821 solute:potassium antiporter activity 1/789 19/18639 0.0526315789473684 1.24334600760456 0.560538943061886 0.92516128688815 GO:0030506 ankyrin binding 1/789 19/18639 0.0526315789473684 1.24334600760456 0.560538943061886 0.92516128688815 GO:0042577 lipid phosphatase activity 1/789 19/18639 0.0526315789473684 1.24334600760456 0.560538943061886 0.92516128688815 GO:0042834 peptidoglycan binding 1/789 19/18639 0.0526315789473684 1.24334600760456 0.560538943061886 0.92516128688815 GO:0046624 sphingolipid transporter activity 1/789 19/18639 0.0526315789473684 1.24334600760456 0.560538943061886 0.92516128688815 GO:0097001 ceramide binding 1/789 19/18639 0.0526315789473684 1.24334600760456 0.560538943061886 0.92516128688815 GO:0120227 acyl-CoA binding 1/789 19/18639 0.0526315789473684 1.24334600760456 0.560538943061886 0.92516128688815 GO:0141147 intracellularly calcium-gated channel activity 1/789 19/18639 0.0526315789473684 1.24334600760456 0.560538943061886 0.92516128688815 GO:0001223 transcription coactivator binding 2/789 44/18639 0.0454545454545455 1.0737988247494 0.561196736661823 0.92516128688815 GO:0016790 thiolester hydrolase activity 2/789 44/18639 0.0454545454545455 1.0737988247494 0.561196736661823 0.92516128688815 GO:0030547 signaling receptor inhibitor activity 2/789 44/18639 0.0454545454545455 1.0737988247494 0.561196736661823 0.92516128688815 GO:0043014 alpha-tubulin binding 2/789 44/18639 0.0454545454545455 1.0737988247494 0.561196736661823 0.92516128688815 GO:0042562 hormone binding 4/789 94/18639 0.0425531914893617 1.00525847423348 0.567072476343112 0.932807296683574 GO:0042605 peptide antigen binding 2/789 45/18639 0.0444444444444444 1.04993662864385 0.57348753347461 0.932807296683574 GO:0046915 transition metal ion transmembrane transporter activity 2/789 45/18639 0.0444444444444444 1.04993662864385 0.57348753347461 0.932807296683574 GO:0051539 4 iron, 4 sulfur cluster binding 2/789 45/18639 0.0444444444444444 1.04993662864385 0.57348753347461 0.932807296683574 GO:0008028 monocarboxylic acid transmembrane transporter activity 3/789 70/18639 0.0428571428571429 1.01243889190657 0.573632623499556 0.932807296683574 GO:0001614 purinergic nucleotide receptor activity 1/789 20/18639 0.05 1.18117870722433 0.579160574314527 0.932807296683574 GO:0016502 nucleotide receptor activity 1/789 20/18639 0.05 1.18117870722433 0.579160574314527 0.932807296683574 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/789 20/18639 0.05 1.18117870722433 0.579160574314527 0.932807296683574 GO:0030627 pre-mRNA 5'-splice site binding 1/789 20/18639 0.05 1.18117870722433 0.579160574314527 0.932807296683574 GO:0030742 GTP-dependent protein binding 1/789 20/18639 0.05 1.18117870722433 0.579160574314527 0.932807296683574 GO:0042288 MHC class I protein binding 1/789 20/18639 0.05 1.18117870722433 0.579160574314527 0.932807296683574 GO:0043024 ribosomal small subunit binding 1/789 20/18639 0.05 1.18117870722433 0.579160574314527 0.932807296683574 GO:0140939 histone H4 methyltransferase activity 1/789 20/18639 0.05 1.18117870722433 0.579160574314527 0.932807296683574 GO:0004896 cytokine receptor activity 4/789 96/18639 0.0416666666666667 0.984315589353612 0.583829675313249 0.933601211181576 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 2/789 46/18639 0.0434782608695652 1.02711191932551 0.585525629644487 0.933601211181576 GO:0030291 protein serine/threonine kinase inhibitor activity 2/789 46/18639 0.0434782608695652 1.02711191932551 0.585525629644487 0.933601211181576 GO:0008514 organic anion transmembrane transporter activity 11/789 269/18639 0.0408921933085502 0.966019760555218 0.590002754859927 0.933601211181576 GO:0005248 voltage-gated sodium channel activity 1/789 21/18639 0.0476190476190476 1.12493210211841 0.596994094206349 0.933601211181576 GO:0008373 sialyltransferase activity 1/789 21/18639 0.0476190476190476 1.12493210211841 0.596994094206349 0.933601211181576 GO:0009975 cyclase activity 1/789 21/18639 0.0476190476190476 1.12493210211841 0.596994094206349 0.933601211181576 GO:0010314 phosphatidylinositol-5-phosphate binding 1/789 21/18639 0.0476190476190476 1.12493210211841 0.596994094206349 0.933601211181576 GO:0015125 bile acid transmembrane transporter activity 1/789 21/18639 0.0476190476190476 1.12493210211841 0.596994094206349 0.933601211181576 GO:0019200 carbohydrate kinase activity 1/789 21/18639 0.0476190476190476 1.12493210211841 0.596994094206349 0.933601211181576 GO:0051010 microtubule plus-end binding 1/789 21/18639 0.0476190476190476 1.12493210211841 0.596994094206349 0.933601211181576 GO:0061891 calcium ion sensor activity 1/789 21/18639 0.0476190476190476 1.12493210211841 0.596994094206349 0.933601211181576 GO:0070182 DNA polymerase binding 1/789 21/18639 0.0476190476190476 1.12493210211841 0.596994094206349 0.933601211181576 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/789 48/18639 0.0416666666666667 0.984315589353612 0.608841607778131 0.933601211181576 GO:0032266 phosphatidylinositol-3-phosphate binding 2/789 48/18639 0.0416666666666667 0.984315589353612 0.608841607778131 0.933601211181576 GO:0140693 molecular condensate scaffold activity 2/789 48/18639 0.0416666666666667 0.984315589353612 0.608841607778131 0.933601211181576 GO:0003684 damaged DNA binding 3/789 74/18639 0.0405405405405405 0.957712465317028 0.611542577833531 0.933601211181576 GO:0048029 monosaccharide binding 3/789 74/18639 0.0405405405405405 0.957712465317028 0.611542577833531 0.933601211181576 GO:0004407 histone deacetylase activity 1/789 22/18639 0.0454545454545455 1.0737988247494 0.614072816930121 0.933601211181576 GO:0005243 gap junction channel activity 1/789 22/18639 0.0454545454545455 1.0737988247494 0.614072816930121 0.933601211181576 GO:0008649 rRNA methyltransferase activity 1/789 22/18639 0.0454545454545455 1.0737988247494 0.614072816930121 0.933601211181576 GO:0016881 acid-amino acid ligase activity 1/789 22/18639 0.0454545454545455 1.0737988247494 0.614072816930121 0.933601211181576 GO:0033558 protein lysine deacetylase activity 1/789 22/18639 0.0454545454545455 1.0737988247494 0.614072816930121 0.933601211181576 GO:0070034 telomerase RNA binding 1/789 22/18639 0.0454545454545455 1.0737988247494 0.614072816930121 0.933601211181576 GO:0140784 metal ion sensor activity 1/789 22/18639 0.0454545454545455 1.0737988247494 0.614072816930121 0.933601211181576 GO:0001222 transcription corepressor binding 2/789 49/18639 0.0408163265306122 0.964227516101498 0.620119660848283 0.933601211181576 GO:0005004 GPI-linked ephrin receptor activity 2/789 49/18639 0.0408163265306122 0.964227516101498 0.620119660848283 0.933601211181576 GO:0005008 hepatocyte growth factor receptor activity 2/789 49/18639 0.0408163265306122 0.964227516101498 0.620119660848283 0.933601211181576 GO:0005009 insulin receptor activity 2/789 49/18639 0.0408163265306122 0.964227516101498 0.620119660848283 0.933601211181576 GO:0005011 macrophage colony-stimulating factor receptor activity 2/789 49/18639 0.0408163265306122 0.964227516101498 0.620119660848283 0.933601211181576 GO:0005018 platelet-derived growth factor alpha-receptor activity 2/789 49/18639 0.0408163265306122 0.964227516101498 0.620119660848283 0.933601211181576 GO:0005020 stem cell factor receptor activity 2/789 49/18639 0.0408163265306122 0.964227516101498 0.620119660848283 0.933601211181576 GO:0008288 boss receptor activity 2/789 49/18639 0.0408163265306122 0.964227516101498 0.620119660848283 0.933601211181576 GO:0016763 pentosyltransferase activity 2/789 49/18639 0.0408163265306122 0.964227516101498 0.620119660848283 0.933601211181576 GO:0036332 placental growth factor receptor activity 2/789 49/18639 0.0408163265306122 0.964227516101498 0.620119660848283 0.933601211181576 GO:0038062 protein tyrosine kinase collagen receptor activity 2/789 49/18639 0.0408163265306122 0.964227516101498 0.620119660848283 0.933601211181576 GO:0060175 brain-derived neurotrophic factor receptor activity 2/789 49/18639 0.0408163265306122 0.964227516101498 0.620119660848283 0.933601211181576 GO:0003725 double-stranded RNA binding 3/789 75/18639 0.04 0.944942965779468 0.620659163429507 0.933601211181576 GO:0008017 microtubule binding 11/789 276/18639 0.0398550724637681 0.941519259381716 0.624112821071908 0.933601211181576 GO:0005216 monoatomic ion channel activity 18/789 448/18639 0.0401785714285714 0.949161461162412 0.624304919278256 0.933601211181576 GO:0005212 structural constituent of eye lens 1/789 23/18639 0.0434782608695652 1.02711191932551 0.630428650170822 0.933601211181576 GO:0043274 phospholipase binding 1/789 23/18639 0.0434782608695652 1.02711191932551 0.630428650170822 0.933601211181576 GO:0099186 structural constituent of postsynapse 1/789 23/18639 0.0434782608695652 1.02711191932551 0.630428650170822 0.933601211181576 GO:0140102 catalytic activity, acting on a rRNA 1/789 23/18639 0.0434782608695652 1.02711191932551 0.630428650170822 0.933601211181576 GO:0005006 epidermal growth factor receptor activity 2/789 50/18639 0.04 0.944942965779468 0.63114527471056 0.933601211181576 GO:0005007 fibroblast growth factor receptor activity 2/789 50/18639 0.04 0.944942965779468 0.63114527471056 0.933601211181576 GO:0005017 platelet-derived growth factor receptor activity 2/789 50/18639 0.04 0.944942965779468 0.63114527471056 0.933601211181576 GO:0005019 platelet-derived growth factor beta-receptor activity 2/789 50/18639 0.04 0.944942965779468 0.63114527471056 0.933601211181576 GO:0015605 organophosphate ester transmembrane transporter activity 2/789 50/18639 0.04 0.944942965779468 0.63114527471056 0.933601211181576 GO:0005319 lipid transporter activity 7/789 178/18639 0.0393258426966292 0.929016960738241 0.632104146616635 0.933601211181576 GO:0001217 DNA-binding transcription repressor activity 11/789 278/18639 0.039568345323741 0.934745739530049 0.633591816227018 0.933601211181576 GO:0005525 GTP binding 15/789 378/18639 0.0396825396825397 0.937443418432012 0.638511198720828 0.933601211181576 GO:0005010 insulin-like growth factor receptor activity 2/789 51/18639 0.0392156862745098 0.926414672332811 0.641919584840002 0.933601211181576 GO:0005030 neurotrophin receptor activity 2/789 51/18639 0.0392156862745098 0.926414672332811 0.641919584840002 0.933601211181576 GO:0016830 carbon-carbon lyase activity 2/789 51/18639 0.0392156862745098 0.926414672332811 0.641919584840002 0.933601211181576 GO:0035591 signaling adaptor activity 5/789 129/18639 0.0387596899224806 0.915642408701035 0.642092606053687 0.933601211181576 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 1/789 24/18639 0.0416666666666667 0.984315589353612 0.646092154415301 0.933601211181576 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 1/789 24/18639 0.0416666666666667 0.984315589353612 0.646092154415301 0.933601211181576 GO:0004622 lysophospholipase activity 1/789 24/18639 0.0416666666666667 0.984315589353612 0.646092154415301 0.933601211181576 GO:0030552 cAMP binding 1/789 24/18639 0.0416666666666667 0.984315589353612 0.646092154415301 0.933601211181576 GO:0035035 histone acetyltransferase binding 1/789 24/18639 0.0416666666666667 0.984315589353612 0.646092154415301 0.933601211181576 GO:0050431 transforming growth factor beta binding 1/789 24/18639 0.0416666666666667 0.984315589353612 0.646092154415301 0.933601211181576 GO:0070300 phosphatidic acid binding 1/789 24/18639 0.0416666666666667 0.984315589353612 0.646092154415301 0.933601211181576 GO:0070840 dynein complex binding 1/789 24/18639 0.0416666666666667 0.984315589353612 0.646092154415301 0.933601211181576 GO:0019199 transmembrane receptor protein kinase activity 3/789 78/18639 0.0384615384615385 0.908599005557181 0.647124960161926 0.933601211181576 GO:0003713 transcription coactivator activity 10/789 256/18639 0.0390625 0.922795865019011 0.647365235445686 0.933601211181576 GO:0030159 signaling receptor complex adaptor activity 2/789 52/18639 0.0384615384615385 0.908599005557181 0.652444082607727 0.939179206553615 GO:0005516 calmodulin binding 8/789 207/18639 0.0386473429951691 0.912988372733785 0.653470393459767 0.939179206553615 GO:0033293 monocarboxylic acid binding 3/789 79/18639 0.0379746835443038 0.897097752322279 0.655650112018692 0.939179206553615 GO:0003707 nuclear steroid receptor activity 1/789 25/18639 0.04 0.944942965779468 0.661092599764016 0.939179206553615 GO:0004709 MAP kinase kinase kinase activity 1/789 25/18639 0.04 0.944942965779468 0.661092599764016 0.939179206553615 GO:0017025 TBP-class protein binding 1/789 25/18639 0.04 0.944942965779468 0.661092599764016 0.939179206553615 GO:0005003 ephrin receptor activity 2/789 53/18639 0.0377358490566038 0.891455628093837 0.662720583191422 0.939179206553615 GO:0005005 transmembrane-ephrin receptor activity 2/789 53/18639 0.0377358490566038 0.891455628093837 0.662720583191422 0.939179206553615 GO:0038064 collagen receptor activity 2/789 53/18639 0.0377358490566038 0.891455628093837 0.662720583191422 0.939179206553615 GO:0051018 protein kinase A binding 2/789 53/18639 0.0377358490566038 0.891455628093837 0.662720583191422 0.939179206553615 GO:1901505 carbohydrate derivative transmembrane transporter activity 2/789 53/18639 0.0377358490566038 0.891455628093837 0.662720583191422 0.939179206553615 GO:0019888 protein phosphatase regulator activity 4/789 107/18639 0.0373831775700935 0.883124267083615 0.668894002075934 0.939179206553615 GO:0030971 receptor tyrosine kinase binding 3/789 81/18639 0.037037037037037 0.874947190536544 0.672253395006703 0.939179206553615 GO:0004112 cyclic-nucleotide phosphodiesterase activity 1/789 26/18639 0.0384615384615385 0.908599005557181 0.67545802034993 0.939179206553615 GO:0004435 phosphatidylinositol phospholipase C activity 1/789 26/18639 0.0384615384615385 0.908599005557181 0.67545802034993 0.939179206553615 GO:0005112 Notch binding 1/789 26/18639 0.0384615384615385 0.908599005557181 0.67545802034993 0.939179206553615 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 1/789 26/18639 0.0384615384615385 0.908599005557181 0.67545802034993 0.939179206553615 GO:0030507 spectrin binding 1/789 26/18639 0.0384615384615385 0.908599005557181 0.67545802034993 0.939179206553615 GO:0034237 protein kinase A regulatory subunit binding 1/789 26/18639 0.0384615384615385 0.908599005557181 0.67545802034993 0.939179206553615 GO:0051139 metal cation:proton antiporter activity 1/789 26/18639 0.0384615384615385 0.908599005557181 0.67545802034993 0.939179206553615 GO:0052742 phosphatidylinositol kinase activity 1/789 26/18639 0.0384615384615385 0.908599005557181 0.67545802034993 0.939179206553615 GO:0070412 R-SMAD binding 1/789 26/18639 0.0384615384615385 0.908599005557181 0.67545802034993 0.939179206553615 GO:0120014 phospholipid transfer activity 1/789 26/18639 0.0384615384615385 0.908599005557181 0.67545802034993 0.939179206553615 GO:0005496 steroid binding 4/789 108/18639 0.037037037037037 0.874947190536544 0.676002615706174 0.939179206553615 GO:0015297 antiporter activity 5/789 135/18639 0.037037037037037 0.874947190536544 0.681279399321061 0.944037572024541 GO:0098632 cell-cell adhesion mediator activity 2/789 55/18639 0.0363636363636364 0.859039059799516 0.682538294407837 0.944037572024541 GO:0008234 cysteine-type peptidase activity 7/789 187/18639 0.0374331550802139 0.884304914499502 0.682611782848515 0.944037572024541 GO:0051020 GTPase binding 12/789 315/18639 0.0380952380952381 0.899945681694731 0.686622488121903 0.945981738285596 GO:0030165 PDZ domain binding 3/789 83/18639 0.036144578313253 0.853864125704338 0.688260877685376 0.945981738285596 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/789 27/18639 0.037037037037037 0.874947190536544 0.68921526646522 0.945981738285596 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 1/789 27/18639 0.037037037037037 0.874947190536544 0.68921526646522 0.945981738285596 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/789 27/18639 0.037037037037037 0.874947190536544 0.68921526646522 0.945981738285596 GO:0019212 phosphatase inhibitor activity 2/789 56/18639 0.0357142857142857 0.84369907658881 0.692084493947955 0.947062991718254 GO:0170055 lipid transmembrane transporter activity 2/789 56/18639 0.0357142857142857 0.84369907658881 0.692084493947955 0.947062991718254 GO:1902936 phosphatidylinositol bisphosphate binding 4/789 111/18639 0.036036036036036 0.851299969170692 0.696687861579132 0.951930861917432 GO:0015932 nucleobase-containing compound transmembrane transporter activity 2/789 57/18639 0.0350877192982456 0.828897338403042 0.70139262342396 0.953992462071553 GO:0016866 intramolecular transferase activity 1/789 28/18639 0.0357142857142857 0.84369907658881 0.702390054492243 0.953992462071553 GO:0051019 mitogen-activated protein kinase binding 1/789 28/18639 0.0357142857142857 0.84369907658881 0.702390054492243 0.953992462071553 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/789 28/18639 0.0357142857142857 0.84369907658881 0.702390054492243 0.953992462071553 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 3/789 86/18639 0.0348837209302326 0.824078167830931 0.711160870343867 0.964465561867241 GO:0004629 phospholipase C activity 1/789 29/18639 0.0344827586206897 0.8146060049823 0.715007014731113 0.966799975342219 GO:0035250 UDP-galactosyltransferase activity 1/789 29/18639 0.0344827586206897 0.8146060049823 0.715007014731113 0.966799975342219 GO:0015459 potassium channel regulator activity 2/789 59/18639 0.0338983050847458 0.800799123541922 0.719306928841785 0.968297788825479 GO:0031593 polyubiquitin modification-dependent protein binding 2/789 59/18639 0.0338983050847458 0.800799123541922 0.719306928841785 0.968297788825479 GO:0070063 RNA polymerase binding 2/789 59/18639 0.0338983050847458 0.800799123541922 0.719306928841785 0.968297788825479 GO:0017124 SH3 domain binding 4/789 115/18639 0.0347826086956522 0.821689535460407 0.722770915563931 0.968431100692883 GO:0035401 histone H3Y41 kinase activity 4/789 115/18639 0.0347826086956522 0.821689535460407 0.722770915563931 0.968431100692883 GO:0140801 histone H2AXY142 kinase activity 4/789 115/18639 0.0347826086956522 0.821689535460407 0.722770915563931 0.968431100692883 GO:0016769 transferase activity, transferring nitrogenous groups 1/789 30/18639 0.0333333333333333 0.78745247148289 0.727089737212422 0.968431100692883 GO:0031210 phosphatidylcholine binding 1/789 30/18639 0.0333333333333333 0.78745247148289 0.727089737212422 0.968431100692883 GO:0048019 receptor antagonist activity 1/789 30/18639 0.0333333333333333 0.78745247148289 0.727089737212422 0.968431100692883 GO:0098918 structural constituent of synapse 1/789 30/18639 0.0333333333333333 0.78745247148289 0.727089737212422 0.968431100692883 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 2/789 60/18639 0.0333333333333333 0.78745247148289 0.727919640520804 0.968431100692883 GO:0003727 single-stranded RNA binding 3/789 89/18639 0.0337078651685393 0.796300252061349 0.732743440674448 0.969857027371601 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 3/789 89/18639 0.0337078651685393 0.796300252061349 0.732743440674448 0.969857027371601 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 3/789 89/18639 0.0337078651685393 0.796300252061349 0.732743440674448 0.969857027371601 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 2/789 61/18639 0.0327868852459016 0.774543414573334 0.736307315298128 0.969857027371601 GO:0016836 hydro-lyase activity 2/789 61/18639 0.0327868852459016 0.774543414573334 0.736307315298128 0.969857027371601 GO:0005164 tumor necrosis factor receptor binding 1/789 31/18639 0.032258064516129 0.762050778854409 0.738660815579846 0.969857027371601 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/789 31/18639 0.032258064516129 0.762050778854409 0.738660815579846 0.969857027371601 GO:0005452 solute:inorganic anion antiporter activity 1/789 31/18639 0.032258064516129 0.762050778854409 0.738660815579846 0.969857027371601 GO:0008327 methyl-CpG binding 1/789 31/18639 0.032258064516129 0.762050778854409 0.738660815579846 0.969857027371601 GO:0140793 histone H2AXY142 phosphatase activity 3/789 90/18639 0.0333333333333333 0.78745247148289 0.73964920548999 0.969857027371601 GO:0008378 galactosyltransferase activity 1/789 32/18639 0.03125 0.738236692015209 0.749741889123887 0.973274064340566 GO:0015106 bicarbonate transmembrane transporter activity 1/789 32/18639 0.03125 0.738236692015209 0.749741889123887 0.973274064340566 GO:0030515 snoRNA binding 1/789 32/18639 0.03125 0.738236692015209 0.749741889123887 0.973274064340566 GO:0031369 translation initiation factor binding 1/789 32/18639 0.03125 0.738236692015209 0.749741889123887 0.973274064340566 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/789 32/18639 0.03125 0.738236692015209 0.749741889123887 0.973274064340566 GO:0042910 xenobiotic transmembrane transporter activity 1/789 32/18639 0.03125 0.738236692015209 0.749741889123887 0.973274064340566 GO:0051059 NF-kappaB binding 1/789 32/18639 0.03125 0.738236692015209 0.749741889123887 0.973274064340566 GO:0052689 carboxylic ester hydrolase activity 3/789 92/18639 0.0326086956521739 0.770333939494131 0.75303501469498 0.97615650053053 GO:0004540 RNA nuclease activity 4/789 121/18639 0.0330578512396694 0.780944599817742 0.758714537094762 0.980059279844921 GO:0015108 chloride transmembrane transporter activity 4/789 121/18639 0.0330578512396694 0.780944599817742 0.758714537094762 0.980059279844921 GO:0030296 protein tyrosine kinase activator activity 1/789 33/18639 0.0303030303030303 0.715865883166263 0.760353683044521 0.980059279844921 GO:0140416 transcription regulator inhibitor activity 1/789 33/18639 0.0303030303030303 0.715865883166263 0.760353683044521 0.980059279844921 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 4/789 122/18639 0.0327868852459016 0.774543414573334 0.76433986515064 0.983803786827556 GO:0160215 deacylase activity 2/789 65/18639 0.0307692307692308 0.726879204445744 0.767680876922978 0.986708471751286 GO:0016831 carboxy-lyase activity 1/789 34/18639 0.0294117647058824 0.694811004249609 0.770516047017319 0.987562820825014 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/789 34/18639 0.0294117647058824 0.694811004249609 0.770516047017319 0.987562820825014 GO:0004867 serine-type endopeptidase inhibitor activity 3/789 95/18639 0.0315789473684211 0.746007604562738 0.772069539895561 0.988162139669425 GO:0008235 metalloexopeptidase activity 2/789 66/18639 0.0303030303030303 0.715865883166263 0.774999010833488 0.990518398677632 GO:0015291 secondary active transmembrane transporter activity 10/789 287/18639 0.0348432055749129 0.823121050330547 0.778142630528064 0.993141365751106 GO:0016229 steroid dehydrogenase activity 1/789 35/18639 0.0285714285714286 0.674959261271048 0.780247992134402 0.994433715465414 GO:0003777 microtubule motor activity 2/789 68/18639 0.0294117647058824 0.694811004249609 0.789032431562721 0.996893736106989 GO:0140223 general transcription initiation factor activity 2/789 68/18639 0.0294117647058824 0.694811004249609 0.789032431562721 0.996893736106989 GO:1990841 promoter-specific chromatin binding 2/789 68/18639 0.0294117647058824 0.694811004249609 0.789032431562721 0.996893736106989 GO:0005484 SNAP receptor activity 1/789 36/18639 0.0277777777777778 0.656210392902408 0.789567726288668 0.996893736106989 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/789 36/18639 0.0277777777777778 0.656210392902408 0.789567726288668 0.996893736106989 GO:0004725 protein tyrosine phosphatase activity 3/789 98/18639 0.0306122448979592 0.723170637076123 0.789886946064527 0.996893736106989 GO:0008170 N-methyltransferase activity 3/789 98/18639 0.0306122448979592 0.723170637076123 0.789886946064527 0.996893736106989 GO:0004519 endonuclease activity 4/789 127/18639 0.031496062992126 0.744049579353912 0.790942063153018 0.996893736106989 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 4/789 128/18639 0.03125 0.738236692015209 0.795963471665478 0.999993120569301 GO:0030551 cyclic nucleotide binding 1/789 37/18639 0.027027027027027 0.638474976878019 0.798492688066781 0.999993120569301 GO:0042805 actinin binding 1/789 37/18639 0.027027027027027 0.638474976878019 0.798492688066781 0.999993120569301 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 9/789 268/18639 0.0335820895522388 0.793328982464105 0.804927974002493 0.999993120569301 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 4/789 130/18639 0.0307692307692308 0.726879204445744 0.805714651325032 0.999993120569301 GO:0000146 microfilament motor activity 1/789 38/18639 0.0263157894736842 0.621673003802281 0.807039579213717 0.999993120569301 GO:0005501 retinoid binding 1/789 38/18639 0.0263157894736842 0.621673003802281 0.807039579213717 0.999993120569301 GO:0019840 isoprenoid binding 1/789 38/18639 0.0263157894736842 0.621673003802281 0.807039579213717 0.999993120569301 GO:0042162 telomeric DNA binding 1/789 38/18639 0.0263157894736842 0.621673003802281 0.807039579213717 0.999993120569301 GO:0031072 heat shock protein binding 4/789 131/18639 0.0305343511450382 0.721330508228601 0.810446423028869 0.999993120569301 GO:0015171 amino acid transmembrane transporter activity 3/789 102/18639 0.0294117647058824 0.694811004249609 0.811827711263013 0.999993120569301 GO:0046943 carboxylic acid transmembrane transporter activity 6/789 188/18639 0.0319148936170213 0.753943855675107 0.812210378874705 0.999993120569301 GO:0005179 hormone activity 4/789 132/18639 0.0303030303030303 0.715865883166263 0.815083698074555 0.999993120569301 GO:0005342 organic acid transmembrane transporter activity 6/789 189/18639 0.0317460317460317 0.749954734745609 0.816111819692035 0.999993120569301 GO:0015144 carbohydrate transmembrane transporter activity 1/789 40/18639 0.025 0.590589353612167 0.823062457652088 0.999993120569301 GO:0050997 quaternary ammonium group binding 1/789 40/18639 0.025 0.590589353612167 0.823062457652088 0.999993120569301 GO:0140662 ATP-dependent protein folding chaperone 1/789 40/18639 0.025 0.590589353612167 0.823062457652088 0.999993120569301 GO:0031491 nucleosome binding 2/789 74/18639 0.027027027027027 0.638474976878019 0.826599009332023 0.999993120569301 GO:0001727 lipid kinase activity 1/789 41/18639 0.024390243902439 0.576184735231383 0.830568437592542 0.999993120569301 GO:0140828 metal cation:monoatomic cation antiporter activity 1/789 41/18639 0.024390243902439 0.576184735231383 0.830568437592542 0.999993120569301 GO:0015103 inorganic anion transmembrane transporter activity 5/789 165/18639 0.0303030303030303 0.715865883166263 0.832689054142809 0.999993120569301 GO:0008236 serine-type peptidase activity 6/789 194/18639 0.0309278350515464 0.730626004468661 0.834668482610411 0.999993120569301 GO:0008307 structural constituent of muscle 1/789 42/18639 0.0238095238095238 0.562466051059207 0.83775638805708 0.999993120569301 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/789 43/18639 0.0232558139534884 0.549385445220621 0.844639767624912 0.999993120569301 GO:0140767 enzyme-substrate adaptor activity 4/789 139/18639 0.0287769784172662 0.679815083294581 0.844991293104781 0.999993120569301 GO:0004620 phospholipase activity 3/789 109/18639 0.0275229357798165 0.650190114068441 0.845557630894173 0.999993120569301 GO:0017171 serine hydrolase activity 6/789 198/18639 0.0303030303030303 0.715865883166263 0.84840571891954 0.999993120569301 GO:0001046 core promoter sequence-specific DNA binding 1/789 44/18639 0.0227272727272727 0.536899412374698 0.851231466019402 0.999993120569301 GO:0016835 carbon-oxygen lyase activity 2/789 79/18639 0.0253164556962025 0.598065168214853 0.853187330109257 0.999993120569301 GO:0140303 intramembrane lipid transporter activity 1/789 45/18639 0.0222222222222222 0.524968314321926 0.857543828122693 0.999993120569301 GO:0015101 organic cation transmembrane transporter activity 2/789 81/18639 0.0246913580246914 0.583298127024363 0.86274101122062 0.999993120569301 GO:0019903 protein phosphatase binding 4/789 144/18639 0.0277777777777778 0.656210392902408 0.863769413147167 0.999993120569301 GO:0061733 protein-lysine-acetyltransferase activity 1/789 47/18639 0.0212765957446809 0.502629237116738 0.869377335820584 0.999993120569301 GO:0099095 ligand-gated monoatomic anion channel activity 1/789 47/18639 0.0212765957446809 0.502629237116738 0.869377335820584 0.999993120569301 GO:0005254 chloride channel activity 2/789 83/18639 0.0240963855421687 0.569242750469559 0.871721998521594 0.999993120569301 GO:0015085 calcium ion transmembrane transporter activity 4/789 147/18639 0.0272108843537415 0.642818344067665 0.874075120346693 0.999993120569301 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/789 48/18639 0.0208333333333333 0.492157794676806 0.874920649183189 0.999993120569301 GO:0004527 exonuclease activity 2/789 84/18639 0.0238095238095238 0.562466051059207 0.876006879956484 0.999993120569301 GO:0035254 glutamate receptor binding 1/789 49/18639 0.0204081632653061 0.482113758050749 0.880229003106833 0.999993120569301 GO:0008509 monoatomic anion transmembrane transporter activity 4/789 149/18639 0.0268456375838926 0.634189909919106 0.880565716025306 0.999993120569301 GO:0004518 nuclease activity 6/789 209/18639 0.0287081339712919 0.678188731420671 0.881435026022715 0.999993120569301 GO:0001216 DNA-binding transcription activator activity 16/789 491/18639 0.0325865580448065 0.769810970085106 0.88852116591995 0.999993120569301 GO:0005272 sodium channel activity 1/789 51/18639 0.0196078431372549 0.463207336166406 0.890180199695929 0.999993120569301 GO:0030544 Hsp70 protein binding 1/789 51/18639 0.0196078431372549 0.463207336166406 0.890180199695929 0.999993120569301 GO:0004864 protein phosphatase inhibitor activity 1/789 53/18639 0.0188679245283019 0.445727814046919 0.899305559668555 0.999993120569301 GO:0005544 calcium-dependent phospholipid binding 1/789 53/18639 0.0188679245283019 0.445727814046919 0.899305559668555 0.999993120569301 GO:0008146 sulfotransferase activity 1/789 53/18639 0.0188679245283019 0.445727814046919 0.899305559668555 0.999993120569301 GO:0016251 RNA polymerase II general transcription initiation factor activity 1/789 53/18639 0.0188679245283019 0.445727814046919 0.899305559668555 0.999993120569301 GO:0017046 peptide hormone binding 1/789 53/18639 0.0188679245283019 0.445727814046919 0.899305559668555 0.999993120569301 GO:0034212 protein N-acetyltransferase activity 1/789 53/18639 0.0188679245283019 0.445727814046919 0.899305559668555 0.999993120569301 GO:0051287 NAD binding 1/789 54/18639 0.0185185185185185 0.437473595268272 0.903580170312132 0.999993120569301 GO:0140597 protein carrier chaperone 5/789 188/18639 0.0265957446808511 0.628286546395923 0.904028598926419 0.999993120569301 GO:0042578 phosphoric ester hydrolase activity 11/789 363/18639 0.0303030303030303 0.715865883166263 0.905396462219748 0.999993120569301 GO:0043177 organic acid binding 5/789 189/18639 0.0264550264550265 0.624962278954674 0.906417641840397 0.999993120569301 GO:0030170 pyridoxal phosphate binding 1/789 56/18639 0.0178571428571429 0.421849538294405 0.911593339192369 0.999993120569301 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/789 56/18639 0.0178571428571429 0.421849538294405 0.911593339192369 0.999993120569301 GO:0001653 peptide receptor activity 3/789 128/18639 0.0234375 0.553677519011407 0.911924941114429 0.999993120569301 GO:0016410 N-acyltransferase activity 2/789 94/18639 0.0212765957446809 0.502629237116738 0.912137220580952 0.999993120569301 GO:0008276 protein methyltransferase activity 2/789 95/18639 0.0210526315789474 0.497338403041825 0.915149428767734 0.999993120569301 GO:0070279 vitamin B6 binding 1/789 57/18639 0.0175438596491228 0.414448669201521 0.91534692340252 0.999993120569301 GO:0016298 lipase activity 3/789 130/18639 0.0230769230769231 0.545159403334308 0.917140048864876 0.999993120569301 GO:0005262 calcium channel activity 3/789 131/18639 0.0229007633587786 0.540997881171451 0.919640680720407 0.999993120569301 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 15/789 484/18639 0.0309917355371901 0.732135562329133 0.92006604079212 0.999993120569301 GO:0061659 ubiquitin-like protein ligase activity 11/789 372/18639 0.0295698924731183 0.698546547283209 0.92024970884406 0.999993120569301 GO:0030594 neurotransmitter receptor activity 2/789 97/18639 0.0206185567010309 0.487084002979107 0.920885202888335 0.999993120569301 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 4/789 167/18639 0.0239520958083832 0.56583411124519 0.926993347240192 0.999993120569301 GO:0000287 magnesium ion binding 6/789 230/18639 0.0260869565217391 0.616267151595305 0.927812055751424 0.999993120569301 GO:0140789 histone phosphatase activity 3/789 136/18639 0.0220588235294118 0.521108253187206 0.931139844333832 0.999993120569301 GO:0016755 aminoacyltransferase activity 15/789 496/18639 0.030241935483871 0.714422605176009 0.935080476805544 0.999993120569301 GO:0005253 monoatomic anion channel activity 2/789 103/18639 0.0194174757281553 0.458710177562848 0.935978015962094 0.999993120569301 GO:0008168 methyltransferase activity 5/789 204/18639 0.0245098039215686 0.579009170208007 0.936482833459921 0.999993120569301 GO:0140030 modification-dependent protein binding 4/789 173/18639 0.023121387283237 0.546209806808941 0.938403550388262 0.999993120569301 GO:0004721 phosphoprotein phosphatase activity 4/789 175/18639 0.0228571428571429 0.539967409016839 0.941830947318468 0.999993120569301 GO:0004252 serine-type endopeptidase activity 4/789 176/18639 0.0227272727272727 0.536899412374698 0.943478662395013 0.999993120569301 GO:0008173 RNA methyltransferase activity 1/789 67/18639 0.0149253731343284 0.352590658872936 0.945151680814487 0.999993120569301 GO:0042054 histone methyltransferase activity 1/789 67/18639 0.0149253731343284 0.352590658872936 0.945151680814487 0.999993120569301 GO:0019787 ubiquitin-like protein transferase activity 14/789 479/18639 0.0292275574112735 0.690459369567461 0.947029815884829 0.999993120569301 GO:0005548 phospholipid transporter activity 1/789 68/18639 0.0147058823529412 0.347405502124804 0.947481818863021 0.999993120569301 GO:0002039 p53 binding 1/789 69/18639 0.0144927536231884 0.342370639775169 0.949713085080083 0.999993120569301 GO:0008080 N-acetyltransferase activity 1/789 69/18639 0.0144927536231884 0.342370639775169 0.949713085080083 0.999993120569301 GO:0016279 protein-lysine N-methyltransferase activity 1/789 69/18639 0.0144927536231884 0.342370639775169 0.949713085080083 0.999993120569301 GO:0098960 postsynaptic neurotransmitter receptor activity 1/789 69/18639 0.0144927536231884 0.342370639775169 0.949713085080083 0.999993120569301 GO:0016278 lysine N-methyltransferase activity 1/789 70/18639 0.0142857142857143 0.337479630635524 0.951849669671996 0.999993120569301 GO:0016782 transferase activity, transferring sulphur-containing groups 1/789 70/18639 0.0142857142857143 0.337479630635524 0.951849669671996 0.999993120569301 GO:0016741 transferase activity, transferring one-carbon groups 5/789 215/18639 0.0232558139534884 0.549385445220621 0.952693531496317 0.999993120569301 GO:0031267 small GTPase binding 7/789 283/18639 0.0247349823321555 0.584328689086243 0.958025315415407 0.999993120569301 GO:0004175 endopeptidase activity 11/789 405/18639 0.0271604938271605 0.641627939726799 0.958970420321611 0.999993120569301 GO:0031406 carboxylic acid binding 4/789 187/18639 0.0213903743315508 0.505317093999715 0.958987011097906 0.999993120569301 GO:0003774 cytoskeletal motor activity 3/789 153/18639 0.0196078431372549 0.463207336166406 0.959828599394992 0.999993120569301 GO:0015294 solute:monoatomic cation symporter activity 2/789 116/18639 0.0172413793103448 0.40730300249115 0.959845116476836 0.999993120569301 GO:0003724 RNA helicase activity 1/789 77/18639 0.012987012987013 0.306799664214113 0.964471231567952 0.999993120569301 GO:0061630 ubiquitin protein ligase activity 9/789 353/18639 0.0254957507082153 0.602300757224873 0.965595967258714 0.999993120569301 GO:0008186 ATP-dependent activity, acting on RNA 1/789 79/18639 0.0126582278481013 0.299032584107427 0.967427502474336 0.999993120569301 GO:0008528 G protein-coupled peptide receptor activity 2/789 122/18639 0.0163934426229508 0.387271707286667 0.967726947845072 0.999993120569301 GO:0015079 potassium ion transmembrane transporter activity 3/789 160/18639 0.01875 0.442942015209125 0.968002990447059 0.999993120569301 GO:0003730 mRNA 3'-UTR binding 6/789 262/18639 0.0229007633587786 0.540997881171451 0.968063060463369 0.999993120569301 GO:0000049 tRNA binding 1/789 80/18639 0.0125 0.295294676806084 0.968812184615917 0.999993120569301 GO:0033192 calmodulin-dependent protein phosphatase activity 1/789 81/18639 0.0123456790123457 0.291649063512181 0.970138074283358 0.999993120569301 GO:0140791 histone H2AXS140 phosphatase activity 1/789 81/18639 0.0123456790123457 0.291649063512181 0.970138074283358 0.999993120569301 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/789 81/18639 0.0123456790123457 0.291649063512181 0.970138074283358 0.999993120569301 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/789 81/18639 0.0123456790123457 0.291649063512181 0.970138074283358 0.999993120569301 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/789 81/18639 0.0123456790123457 0.291649063512181 0.970138074283358 0.999993120569301 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/789 81/18639 0.0123456790123457 0.291649063512181 0.970138074283358 0.999993120569301 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/789 81/18639 0.0123456790123457 0.291649063512181 0.970138074283358 0.999993120569301 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/789 81/18639 0.0123456790123457 0.291649063512181 0.970138074283358 0.999993120569301 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/789 82/18639 0.0121951219512195 0.288092367615691 0.971407664723623 0.999993120569301 GO:0033549 MAP kinase phosphatase activity 1/789 82/18639 0.0121951219512195 0.288092367615691 0.971407664723623 0.999993120569301 GO:0015081 sodium ion transmembrane transporter activity 3/789 164/18639 0.0182926829268293 0.432138551423537 0.971941127813029 0.999993120569301 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/789 83/18639 0.0120481927710843 0.284621375234779 0.972623343579745 0.999993120569301 GO:0019783 ubiquitin-like protein peptidase activity 2/789 127/18639 0.015748031496063 0.372024789676956 0.97313693223923 0.999993120569301 GO:0017018 myosin phosphatase activity 1/789 84/18639 0.0119047619047619 0.281233025529603 0.973787397358339 0.999993120569301 GO:0031490 chromatin DNA binding 2/789 128/18639 0.015625 0.369118346007605 0.974108551145973 0.999993120569301 GO:0050660 flavin adenine dinucleotide binding 1/789 86/18639 0.0116279069767442 0.27469272261031 0.975969295518953 0.999993120569301 GO:0016791 phosphatase activity 6/789 273/18639 0.021978021978022 0.51919943174696 0.976217636515706 0.999993120569301 GO:0016779 nucleotidyltransferase activity 2/789 136/18639 0.0147058823529412 0.347405502124804 0.980748861659092 0.999993120569301 GO:0099094 ligand-gated monoatomic cation channel activity 2/789 136/18639 0.0147058823529412 0.347405502124804 0.980748861659092 0.999993120569301 GO:0051213 dioxygenase activity 1/789 93/18639 0.010752688172043 0.254016926284803 0.982273173122008 0.999993120569301 GO:0016887 ATP hydrolysis activity 10/789 417/18639 0.0239808153477218 0.566512569412151 0.984126027192615 0.999993120569301 GO:0016407 acetyltransferase activity 1/789 96/18639 0.0104166666666667 0.246078897338403 0.984440848867377 0.999993120569301 GO:0004842 ubiquitin-protein transferase activity 11/789 449/18639 0.0244988864142539 0.578751259664485 0.984457793603978 0.999993120569301 GO:0140098 catalytic activity, acting on RNA 9/789 387/18639 0.0232558139534884 0.549385445220621 0.984699722326743 0.999993120569301 GO:0140996 histone H3 kinase activity 8/789 357/18639 0.0224089635854342 0.529379812761607 0.985477093910504 0.999993120569301 GO:0008237 metallopeptidase activity 3/789 184/18639 0.016304347826087 0.385166969747066 0.985639457432547 0.999993120569301 GO:0008194 UDP-glycosyltransferase activity 2/789 145/18639 0.0137931034482759 0.32584240199292 0.986250945084794 0.999993120569301 GO:0035173 histone kinase activity 8/789 360/18639 0.0222222222222222 0.524968314321926 0.986557036226229 0.999993120569301 GO:0015276 ligand-gated monoatomic ion channel activity 3/789 186/18639 0.0161290322580645 0.381025389427205 0.986584747457141 0.999993120569301 GO:0015293 symporter activity 2/789 146/18639 0.0136986301369863 0.323610604718996 0.986758256034685 0.999993120569301 GO:0043130 ubiquitin binding 1/789 100/18639 0.01 0.236235741444867 0.986924914954266 0.999993120569301 GO:0022834 ligand-gated channel activity 3/789 188/18639 0.0159574468085106 0.376971927837554 0.987470163815275 0.999993120569301 GO:0004722 protein serine/threonine phosphatase activity 1/789 103/18639 0.00970873786407767 0.229355088781424 0.988524343052015 0.999993120569301 GO:0019842 vitamin binding 2/789 150/18639 0.0133333333333333 0.314980988593156 0.988611325379861 0.999993120569301 GO:0000510 H3-H4 histone complex chaperone activity 2/789 151/18639 0.0132450331125828 0.312895021781281 0.989033558701849 0.999993120569301 GO:0140584 chromatin extrusion motor activity 2/789 151/18639 0.0132450331125828 0.312895021781281 0.989033558701849 0.999993120569301 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 2/789 151/18639 0.0132450331125828 0.312895021781281 0.989033558701849 0.999993120569301 GO:0140849 ATP-dependent H2AZ histone chaperone activity 2/789 151/18639 0.0132450331125828 0.312895021781281 0.989033558701849 0.999993120569301 GO:0016757 glycosyltransferase activity 5/789 267/18639 0.0187265917602996 0.442389028922972 0.989370254759294 0.999993120569301 GO:0015616 DNA translocase activity 2/789 152/18639 0.0131578947368421 0.310836501901141 0.989440513395672 0.999993120569301 GO:0140674 ATP-dependent histone chaperone activity 2/789 152/18639 0.0131578947368421 0.310836501901141 0.989440513395672 0.999993120569301 GO:0061775 cohesin loader activity 2/789 153/18639 0.0130718954248366 0.308804890777604 0.989832724177138 0.999993120569301 GO:0004497 monooxygenase activity 1/789 106/18639 0.00943396226415094 0.222863907023459 0.989928336267227 0.999993120569301 GO:0004843 cysteine-type deubiquitinase activity 1/789 108/18639 0.00925925925925926 0.218736797634136 0.99076766017991 0.999993120569301 GO:0004222 metalloendopeptidase activity 1/789 110/18639 0.00909090909090909 0.214759764949879 0.991537120115917 0.999993120569301 GO:0140658 ATP-dependent chromatin remodeler activity 2/789 158/18639 0.0126582278481013 0.299032584107427 0.991590117608977 0.999993120569301 GO:0003689 DNA clamp loader activity 2/789 160/18639 0.0125 0.295294676806084 0.992206679915455 0.999993120569301 GO:0046873 metal ion transmembrane transporter activity 10/789 450/18639 0.0222222222222222 0.524968314321926 0.992920146514043 0.999993120569301 GO:0101005 deubiquitinase activity 1/789 115/18639 0.00869565217391304 0.205422383865102 0.993192056833917 0.999993120569301 GO:0140713 histone chaperone activity 2/789 164/18639 0.0121951219512195 0.288092367615691 0.993310093673235 0.999993120569301 GO:0141003 histone H2AX kinase activity 7/789 354/18639 0.019774011299435 0.467132822066121 0.993574333550454 0.999993120569301 GO:0035403 histone H3T6 kinase activity 4/789 247/18639 0.0161943319838057 0.382568002339865 0.993701230011811 0.999993120569301 GO:0045182 translation regulator activity 7/789 356/18639 0.0196629213483146 0.46450848036912 0.993926136126067 0.999993120569301 GO:0032182 ubiquitin-like protein binding 1/789 120/18639 0.00833333333333333 0.196863117870722 0.994523695453715 0.999993120569301 GO:0106310 protein serine kinase activity 7/789 361/18639 0.0193905817174515 0.458074844906944 0.994727496243597 0.999993120569301 GO:0005267 potassium channel activity 1/789 124/18639 0.00806451612903226 0.190512694713602 0.995399064497704 0.999993120569301 GO:0003823 antigen binding 2/789 174/18639 0.0114942528735632 0.2715353349941 0.995442405155118 0.999993120569301 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 2/789 181/18639 0.0110497237569061 0.261033968447367 0.99652208762627 0.999993120569301 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 3/789 229/18639 0.0131004366812227 0.309479137264018 0.997020404096238 0.999993120569301 GO:0140101 catalytic activity, acting on a tRNA 1/789 139/18639 0.00719424460431655 0.169953770823645 0.99760645339142 0.999993120569301 GO:0016758 hexosyltransferase activity 2/789 197/18639 0.0101522842639594 0.23983324004555 0.998134181402777 0.999993120569301 GO:0004674 protein serine/threonine kinase activity 8/789 433/18639 0.0184757505773672 0.436463263639477 0.998175547182378 0.999993120569301 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 3/789 243/18639 0.0123456790123457 0.291649063512181 0.998200443851876 0.999993120569301 GO:0004676 3-phosphoinositide-dependent protein kinase activity 3/789 245/18639 0.0122448979591837 0.289268254830449 0.998326349255546 0.999993120569301 GO:0004711 ribosomal protein S6 kinase activity 3/789 245/18639 0.0122448979591837 0.289268254830449 0.998326349255546 0.999993120569301 GO:0035175 histone H3S10 kinase activity 3/789 245/18639 0.0122448979591837 0.289268254830449 0.998326349255546 0.999993120569301 GO:0035979 histone H2AXS139 kinase activity 3/789 245/18639 0.0122448979591837 0.289268254830449 0.998326349255546 0.999993120569301 GO:0044022 histone H3S28 kinase activity 3/789 245/18639 0.0122448979591837 0.289268254830449 0.998326349255546 0.999993120569301 GO:0044023 histone H4S1 kinase activity 3/789 245/18639 0.0122448979591837 0.289268254830449 0.998326349255546 0.999993120569301 GO:0044024 histone H2AS1 kinase activity 3/789 245/18639 0.0122448979591837 0.289268254830449 0.998326349255546 0.999993120569301 GO:0044025 histone H2BS14 kinase activity 3/789 245/18639 0.0122448979591837 0.289268254830449 0.998326349255546 0.999993120569301 GO:0072354 histone H3T3 kinase activity 3/789 245/18639 0.0122448979591837 0.289268254830449 0.998326349255546 0.999993120569301 GO:0072371 histone H2AS121 kinase activity 3/789 245/18639 0.0122448979591837 0.289268254830449 0.998326349255546 0.999993120569301 GO:0072518 Rho-dependent protein serine/threonine kinase activity 3/789 245/18639 0.0122448979591837 0.289268254830449 0.998326349255546 0.999993120569301 GO:0140823 histone H2BS36 kinase activity 3/789 245/18639 0.0122448979591837 0.289268254830449 0.998326349255546 0.999993120569301 GO:0140855 histone H3S57 kinase activity 3/789 245/18639 0.0122448979591837 0.289268254830449 0.998326349255546 0.999993120569301 GO:0140995 histone H2A kinase activity 3/789 245/18639 0.0122448979591837 0.289268254830449 0.998326349255546 0.999993120569301 GO:0140997 histone H4 kinase activity 3/789 245/18639 0.0122448979591837 0.289268254830449 0.998326349255546 0.999993120569301 GO:0140998 histone H2B kinase activity 3/789 245/18639 0.0122448979591837 0.289268254830449 0.998326349255546 0.999993120569301 GO:1990244 histone H2AT120 kinase activity 3/789 245/18639 0.0122448979591837 0.289268254830449 0.998326349255546 0.999993120569301 GO:0004677 DNA-dependent protein kinase activity 3/789 246/18639 0.0121951219512195 0.288092367615691 0.998386031416491 0.999993120569301 GO:0140857 histone H3T45 kinase activity 3/789 246/18639 0.0121951219512195 0.288092367615691 0.998386031416491 0.999993120569301 GO:0035402 histone H3T11 kinase activity 3/789 247/18639 0.0121457489878543 0.286926001754899 0.998443631433761 0.999993120569301 GO:0042393 histone binding 3/789 247/18639 0.0121457489878543 0.286926001754899 0.998443631433761 0.999993120569301 GO:0004679 AMP-activated protein kinase activity 3/789 248/18639 0.0120967741935484 0.285769042070404 0.998499219967885 0.999993120569301 GO:0004386 helicase activity 1/789 155/18639 0.00645161290322581 0.152410155770882 0.998808598901803 0.999993120569301 GO:0008094 ATP-dependent activity, acting on DNA 2/789 210/18639 0.00952380952380952 0.224986420423683 0.998880007261386 0.999993120569301 GO:0022836 gated channel activity 4/789 318/18639 0.0125786163522013 0.297151876031279 0.999435614814703 0.999993120569301 GO:0022832 voltage-gated channel activity 1/789 175/18639 0.00571428571428571 0.13499185225421 0.999502319135715 0.999993120569301 GO:0030371 translation repressor activity 3/789 329/18639 0.00911854103343465 0.215412530192888 0.999927414497416 0.999993120569301 GO:0140097 catalytic activity, acting on DNA 2/789 336/18639 0.00595238095238095 0.140616512764802 0.999993120569301 0.999993120569301