ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0009055 electron transfer activity 43/1952 116/18639 0.370689655172414 3.53959246042962 2.69289319447214e-14 3.42266725017409e-11 GO:0003735 structural constituent of ribosome 51/1952 175/18639 0.291428571428571 2.78275468384075 5.69960421391968e-12 3.06380958775267e-09 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 29/1952 68/18639 0.426470588235294 4.07222607280617 7.23165126928246e-12 3.06380958775267e-09 GO:0022853 active monoatomic ion transmembrane transporter activity 39/1952 118/18639 0.330508474576271 3.1559157057516 2.6413361870146e-11 8.3928457342389e-09 GO:0015399 primary active transmembrane transporter activity 44/1952 166/18639 0.265060240963855 2.53097224965436 4.28376793125007e-09 1.08893380812377e-06 GO:0015078 proton transmembrane transporter activity 46/1952 185/18639 0.248648648648649 2.37426340274701 1.6956712845045e-08 3.59199700434204e-06 GO:0003954 NADH dehydrogenase activity 19/1952 44/18639 0.431818181818182 4.12328846870343 2.35466050643668e-08 4.27539071954432e-06 GO:0008137 NADH dehydrogenase (ubiquinone) activity 18/1952 41/18639 0.439024390243902 4.19209816073571 4.02460237881946e-08 6.39408702934942e-06 GO:0016651 oxidoreductase activity, acting on NAD(P)H 26/1952 88/18639 0.295454545454545 2.8211973733234 6.40495919125853e-07 9.04522570232178e-05 GO:0016675 oxidoreductase activity, acting on a heme group of donors 9/1952 16/18639 0.5625 5.37112576844262 8.57192611069515e-06 0.00108949180866935 GO:0035325 Toll-like receptor binding 8/1952 13/18639 0.615384615384615 5.87610340479193 1.131473983667e-05 0.00130546124950475 GO:0031720 haptoglobin binding 7/1952 10/18639 0.7 6.68406762295082 1.23253619150723e-05 0.00130546124950475 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 18/1952 58/18639 0.310344827586207 2.96337973431317 1.56762050024703e-05 0.00153265050447229 GO:0005344 oxygen carrier activity 8/1952 14/18639 0.571428571428571 5.45638173302108 2.39679770532325e-05 0.00217594991676132 GO:0048407 platelet-derived growth factor binding 7/1952 11/18639 0.636363636363636 6.07642511177347 3.08133874116551e-05 0.00261092102668091 GO:0004129 cytochrome-c oxidase activity 8/1952 15/18639 0.533333333333333 5.09262295081967 4.66330669871361e-05 0.00370441425879062 GO:0140104 molecular carrier activity 44/1952 249/18639 0.176706827309237 1.6873148331029 0.000365790311431564 0.0267974412242727 GO:0019864 IgG binding 6/1952 11/18639 0.545454545454545 5.20836438152012 0.000379507428825262 0.0267974412242727 GO:0016004 phospholipase activator activity 8/1952 20/18639 0.4 3.81946721311475 0.00056452780561464 0.0360423566357577 GO:0004601 peroxidase activity 15/1952 57/18639 0.263157894736842 2.51280737704918 0.000589150784667366 0.0360423566357577 GO:0005201 extracellular matrix structural constituent 32/1952 168/18639 0.19047619047619 1.81879391100703 0.000595507072660041 0.0360423566357577 GO:0022804 active transmembrane transporter activity 70/1952 457/18639 0.153172866520788 1.46259685403738 0.000730534031559469 0.0422049433687312 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 15/1952 59/18639 0.254237288135593 2.42762746596277 0.000871875358203112 0.0481805904467894 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 14/1952 54/18639 0.259259259259259 2.4755806010929 0.00104202827704492 0.0551840808385036 GO:0022884 macromolecule transmembrane transporter activity 10/1952 32/18639 0.3125 2.9839587602459 0.00114697213345321 0.0578614050498438 GO:0140517 protein-RNA adaptor activity 8/1952 22/18639 0.363636363636364 3.47224292101341 0.00118363220400939 0.0578614050498438 GO:0016504 peptidase activator activity 14/1952 57/18639 0.245614035087719 2.3452868852459 0.00183221372260074 0.0841145945663557 GO:0019763 immunoglobulin receptor activity 6/1952 14/18639 0.428571428571429 4.09228629976581 0.00186878394114635 0.0841145945663557 GO:0015035 protein-disulfide reductase activity 10/1952 34/18639 0.294117647058824 2.80843177434908 0.00191921576901992 0.0841145945663557 GO:0060229 lipase activator activity 8/1952 24/18639 0.333333333333333 3.18288934426229 0.00224997010420767 0.0953237334149317 GO:0140318 protein transporter activity 11/1952 41/18639 0.268292682926829 2.56183776489404 0.00261326907945216 0.107144032257539 GO:0016209 antioxidant activity 18/1952 86/18639 0.209302325581395 1.99855842546702 0.00310039585927307 0.118904864856232 GO:0140375 immune receptor activity 28/1952 156/18639 0.179487179487179 1.71386349306431 0.00314053123486643 0.118904864856232 GO:0051287 NAD binding 13/1952 54/18639 0.240740740740741 2.29875341530055 0.00318077529906522 0.118904864856232 GO:0043425 bHLH transcription factor binding 9/1952 32/18639 0.28125 2.68556288422131 0.0044610600601097 0.162000209611412 GO:0030020 extracellular matrix structural constituent conferring tensile strength 11/1952 44/18639 0.25 2.38716700819672 0.00473413201596416 0.167141160896957 GO:0005021 vascular endothelial growth factor receptor activity 12/1952 51/18639 0.235294117647059 2.24674541947927 0.00549860490501368 0.188884509034389 GO:0032977 membrane insertase activity 6/1952 17/18639 0.352941176470588 3.3701181292189 0.00584631533108135 0.195543862784326 GO:0015036 disulfide oxidoreductase activity 10/1952 40/18639 0.25 2.38716700819672 0.0069424115583039 0.226251412579596 GO:0043274 phospholipase binding 7/1952 23/18639 0.304347826086957 2.9061163578047 0.00739403442782959 0.234945443944285 GO:0016860 intramolecular oxidoreductase activity 12/1952 53/18639 0.226415094339623 2.16196257346118 0.00759868841543742 0.23555934087856 GO:0008035 high-density lipoprotein particle binding 5/1952 13/18639 0.384615384615385 3.67256462799496 0.00784495001405278 0.236565870858079 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 6/1952 18/18639 0.333333333333333 3.18288934426229 0.0080034086915007 0.236565870858079 GO:0140297 DNA-binding transcription factor binding 68/1952 488/18639 0.139344262295082 1.33055210292932 0.00879553313917219 0.240521503962468 GO:0042625 ATPase-coupled ion transmembrane transporter activity 7/1952 24/18639 0.291666666666667 2.78502817622951 0.00951217856108567 0.240521503962468 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 7/1952 24/18639 0.291666666666667 2.78502817622951 0.00951217856108567 0.240521503962468 GO:0046961 proton-transporting ATPase activity, rotational mechanism 7/1952 24/18639 0.291666666666667 2.78502817622951 0.00951217856108567 0.240521503962468 GO:0030145 manganese ion binding 14/1952 68/18639 0.205882352941176 1.96590224204436 0.0098702899197022 0.240521503962468 GO:0005004 GPI-linked ephrin receptor activity 11/1952 49/18639 0.224489795918367 2.14357853797257 0.0110694656429249 0.240521503962468 GO:0005008 hepatocyte growth factor receptor activity 11/1952 49/18639 0.224489795918367 2.14357853797257 0.0110694656429249 0.240521503962468 GO:0005009 insulin receptor activity 11/1952 49/18639 0.224489795918367 2.14357853797257 0.0110694656429249 0.240521503962468 GO:0005011 macrophage colony-stimulating factor receptor activity 11/1952 49/18639 0.224489795918367 2.14357853797257 0.0110694656429249 0.240521503962468 GO:0005018 platelet-derived growth factor alpha-receptor activity 11/1952 49/18639 0.224489795918367 2.14357853797257 0.0110694656429249 0.240521503962468 GO:0005020 stem cell factor receptor activity 11/1952 49/18639 0.224489795918367 2.14357853797257 0.0110694656429249 0.240521503962468 GO:0008288 boss receptor activity 11/1952 49/18639 0.224489795918367 2.14357853797257 0.0110694656429249 0.240521503962468 GO:0036332 placental growth factor receptor activity 11/1952 49/18639 0.224489795918367 2.14357853797257 0.0110694656429249 0.240521503962468 GO:0038062 protein tyrosine kinase collagen receptor activity 11/1952 49/18639 0.224489795918367 2.14357853797257 0.0110694656429249 0.240521503962468 GO:0060175 brain-derived neurotrophic factor receptor activity 11/1952 49/18639 0.224489795918367 2.14357853797257 0.0110694656429249 0.240521503962468 GO:0005161 platelet-derived growth factor receptor binding 5/1952 14/18639 0.357142857142857 3.41023858313817 0.0111650422767786 0.240521503962468 GO:0042826 histone deacetylase binding 22/1952 127/18639 0.173228346456693 1.65409997418355 0.012325845804546 0.251923651207538 GO:0017147 Wnt-protein binding 8/1952 31/18639 0.258064516129032 2.46417239555791 0.0124509271332873 0.251923651207538 GO:0005006 epidermal growth factor receptor activity 11/1952 50/18639 0.22 2.10070696721311 0.0128835856243037 0.251923651207538 GO:0005007 fibroblast growth factor receptor activity 11/1952 50/18639 0.22 2.10070696721311 0.0128835856243037 0.251923651207538 GO:0005017 platelet-derived growth factor receptor activity 11/1952 50/18639 0.22 2.10070696721311 0.0128835856243037 0.251923651207538 GO:0005019 platelet-derived growth factor beta-receptor activity 11/1952 50/18639 0.22 2.10070696721311 0.0128835856243037 0.251923651207538 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 50/1952 349/18639 0.143266475644699 1.36800401615858 0.0137413610587469 0.259632901580372 GO:0002020 protease binding 23/1952 136/18639 0.169117647058824 1.61484827025072 0.0140789765292158 0.259632901580372 GO:0140789 histone phosphatase activity 23/1952 136/18639 0.169117647058824 1.61484827025072 0.0140789765292158 0.259632901580372 GO:0005010 insulin-like growth factor receptor activity 11/1952 51/18639 0.215686274509804 2.05951663452266 0.0149144553221084 0.259632901580372 GO:0005030 neurotrophin receptor activity 11/1952 51/18639 0.215686274509804 2.05951663452266 0.0149144553221084 0.259632901580372 GO:0008239 dipeptidyl-peptidase activity 4/1952 10/18639 0.4 3.81946721311475 0.0149959965571118 0.259632901580372 GO:0141109 transporter activator activity 4/1952 10/18639 0.4 3.81946721311475 0.0149959965571118 0.259632901580372 GO:0140142 nucleocytoplasmic carrier activity 8/1952 32/18639 0.25 2.38716700819672 0.0151142161576798 0.259632901580372 GO:0004721 phosphoprotein phosphatase activity 28/1952 175/18639 0.16 1.5277868852459 0.0151163137033419 0.259632901580372 GO:0008408 3'-5' exonuclease activity 12/1952 58/18639 0.206896551724138 1.97558648954211 0.0156072368480053 0.264490640450863 GO:0038024 cargo receptor activity 13/1952 65/18639 0.2 1.90973360655738 0.015996487803991 0.267520210511481 GO:0005178 integrin binding 26/1952 161/18639 0.161490683229814 1.54202092454943 0.0167516503081134 0.276511007033924 GO:0042578 phosphoric ester hydrolase activity 51/1952 363/18639 0.140495867768595 1.34154840130064 0.0182311836355785 0.293768822577188 GO:0001671 ATPase activator activity 7/1952 27/18639 0.259259259259259 2.4755806010929 0.018490563183458 0.293768822577188 GO:0008320 protein transmembrane transporter activity 7/1952 27/18639 0.259259259259259 2.4755806010929 0.018490563183458 0.293768822577188 GO:0005003 ephrin receptor activity 11/1952 53/18639 0.207547169811321 1.98179902567275 0.0196854379820664 0.298168960632497 GO:0005005 transmembrane-ephrin receptor activity 11/1952 53/18639 0.207547169811321 1.98179902567275 0.0196854379820664 0.298168960632497 GO:0038064 collagen receptor activity 11/1952 53/18639 0.207547169811321 1.98179902567275 0.0196854379820664 0.298168960632497 GO:0004714 transmembrane receptor protein tyrosine kinase activity 12/1952 60/18639 0.2 1.90973360655738 0.0201715557155004 0.298168960632497 GO:0016500 protein-hormone receptor activity 13/1952 67/18639 0.194029850746269 1.85272663322731 0.020334730345858 0.298168960632497 GO:0050840 extracellular matrix binding 13/1952 67/18639 0.194029850746269 1.85272663322731 0.020334730345858 0.298168960632497 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 5/1952 16/18639 0.3125 2.9839587602459 0.0204096770849939 0.298168960632497 GO:0004896 cytokine receptor activity 17/1952 96/18639 0.177083333333333 1.69090996413934 0.0210236410805489 0.300028501689653 GO:0019825 oxygen binding 8/1952 34/18639 0.235294117647059 2.24674541947927 0.0216369864127604 0.300028501689653 GO:0001851 complement component C3b binding 4/1952 11/18639 0.363636363636364 3.47224292101341 0.0216410593889886 0.300028501689653 GO:0050786 RAGE receptor binding 4/1952 11/18639 0.363636363636364 3.47224292101341 0.0216410593889886 0.300028501689653 GO:0051087 protein-folding chaperone binding 22/1952 134/18639 0.164179104477612 1.56769176657695 0.0220650318641724 0.300028501689653 GO:0030021 extracellular matrix structural constituent conferring compression resistance 6/1952 22/18639 0.272727272727273 2.60418219076006 0.0223708723146838 0.300028501689653 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 11/1952 54/18639 0.203703703703704 1.94509904371585 0.0224544932248246 0.300028501689653 GO:0051537 2 iron, 2 sulfur cluster binding 7/1952 28/18639 0.25 2.38716700819672 0.0224848787930754 0.300028501689653 GO:0020037 heme binding 23/1952 142/18639 0.161971830985915 1.54661524474717 0.0226614761307684 0.300028501689653 GO:0032182 ubiquitin-like protein binding 20/1952 120/18639 0.166666666666667 1.59144467213115 0.0242711150725189 0.318026672754346 GO:0001540 amyloid-beta binding 15/1952 83/18639 0.180722891566265 1.72566289749161 0.0245357282719268 0.318213373812438 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 21/1952 128/18639 0.1640625 1.5665783491291 0.0250599303753208 0.321729005121542 GO:0030695 GTPase regulator activity 65/1952 489/18639 0.132924335378323 1.26925035200644 0.0261904506463068 0.329933463109837 GO:0004540 RNA nuclease activity 20/1952 121/18639 0.165289256198347 1.57829223682428 0.0263131170918974 0.329933463109837 GO:0051787 misfolded protein binding 5/1952 17/18639 0.294117647058824 2.80843177434908 0.0264777444824574 0.329933463109837 GO:0004527 exonuclease activity 15/1952 84/18639 0.178571428571429 1.70511929156909 0.027076551945924 0.332497807132192 GO:0060589 nucleoside-triphosphatase regulator activity 65/1952 490/18639 0.13265306122449 1.26666004516561 0.0272067442499984 0.332497807132192 GO:0016763 pentosyltransferase activity 10/1952 49/18639 0.204081632653061 1.94870776179324 0.0284353206654951 0.333693971348572 GO:0005507 copper ion binding 12/1952 63/18639 0.19047619047619 1.81879391100703 0.0287799721364784 0.333693971348572 GO:0016798 hydrolase activity, acting on glycosyl bonds 21/1952 130/18639 0.161538461538462 1.54247714375788 0.0292232897215935 0.333693971348572 GO:0005049 nuclear export signal receptor activity 4/1952 12/18639 0.333333333333333 3.18288934426229 0.0298225343755192 0.333693971348572 GO:0097677 STAT family protein binding 4/1952 12/18639 0.333333333333333 3.18288934426229 0.0298225343755192 0.333693971348572 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 4/1952 12/18639 0.333333333333333 3.18288934426229 0.0298225343755192 0.333693971348572 GO:1990247 N6-methyladenosine-containing RNA reader activity 4/1952 12/18639 0.333333333333333 3.18288934426229 0.0298225343755192 0.333693971348572 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 8/1952 36/18639 0.222222222222222 2.1219262295082 0.0299300650934203 0.333693971348572 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 8/1952 36/18639 0.222222222222222 2.1219262295082 0.0299300650934203 0.333693971348572 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 8/1952 36/18639 0.222222222222222 2.1219262295082 0.0299300650934203 0.333693971348572 GO:0043130 ubiquitin binding 17/1952 100/18639 0.17 1.62327356557377 0.0301959853559756 0.333731281629956 GO:0005539 glycosaminoglycan binding 35/1952 242/18639 0.144628099173554 1.38100570722124 0.0306040632561016 0.334126626438259 GO:0019199 transmembrane receptor protein kinase activity 14/1952 78/18639 0.179487179487179 1.71386349306431 0.0307575258011615 0.334126626438259 GO:0035925 mRNA 3'-UTR AU-rich region binding 7/1952 30/18639 0.233333333333333 2.22802254098361 0.0321773318431556 0.346588040446193 GO:0045296 cadherin binding 46/1952 334/18639 0.137724550898204 1.31508601649161 0.0324699435145258 0.346800825268591 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 5/1952 18/18639 0.277777777777778 2.65240778688525 0.0335832582482101 0.355702676945625 GO:0043394 proteoglycan binding 8/1952 37/18639 0.216216216216216 2.06457687195392 0.0347992411551102 0.363646606232101 GO:0005518 collagen binding 13/1952 72/18639 0.180555555555556 1.72406506147541 0.0349630282819886 0.363646606232101 GO:0008201 heparin binding 26/1952 172/18639 0.151162790697674 1.44340330728174 0.0354343160623108 0.363646606232101 GO:0016853 isomerase activity 27/1952 180/18639 0.15 1.43230020491803 0.0354777176811806 0.363646606232101 GO:0004722 protein serine/threonine phosphatase activity 17/1952 103/18639 0.16504854368932 1.57599375298424 0.038812425688595 0.393391087082276 GO:0051011 microtubule minus-end binding 4/1952 13/18639 0.307692307692308 2.93805170239597 0.039590349647282 0.393391087082276 GO:0005109 frizzled binding 8/1952 38/18639 0.210526315789474 2.01024590163934 0.0401769732787498 0.393391087082276 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 8/1952 38/18639 0.210526315789474 2.01024590163934 0.0401769732787498 0.393391087082276 GO:0017025 TBP-class protein binding 6/1952 25/18639 0.24 2.29168032786885 0.0405462096048609 0.393391087082276 GO:0017056 structural constituent of nuclear pore 6/1952 25/18639 0.24 2.29168032786885 0.0405462096048609 0.393391087082276 GO:0120020 cholesterol transfer activity 6/1952 25/18639 0.24 2.29168032786885 0.0405462096048609 0.393391087082276 GO:0008009 chemokine activity 9/1952 45/18639 0.2 1.90973360655738 0.0411166806177448 0.395903795948134 GO:0003756 protein disulfide isomerase activity 5/1952 19/18639 0.263157894736842 2.51280737704918 0.0417636999060267 0.396001049551614 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 5/1952 19/18639 0.263157894736842 2.51280737704918 0.0417636999060267 0.396001049551614 GO:0016791 phosphatase activity 38/1952 273/18639 0.139194139194139 1.32911862727436 0.0420614804795184 0.396001049551614 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 15/1952 89/18639 0.168539325842697 1.60932607294161 0.0427704602981475 0.396797482036098 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 15/1952 89/18639 0.168539325842697 1.60932607294161 0.0427704602981475 0.396797482036098 GO:0120015 sterol transfer activity 7/1952 32/18639 0.21875 2.08877113217213 0.0443195286601064 0.408155783575233 GO:0044325 transmembrane transporter binding 21/1952 136/18639 0.154411764705882 1.47442668153327 0.0448467096801658 0.408155783575233 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 11/1952 60/18639 0.183333333333333 1.75058913934426 0.045276617214854 0.408155783575233 GO:0046906 tetrapyrrole binding 23/1952 152/18639 0.151315789473684 1.44486424180328 0.0452792804753013 0.408155783575233 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 8/1952 39/18639 0.205128205128205 1.95870113493064 0.0460800925896638 0.412449279446921 GO:0140793 histone H2AXY142 phosphatase activity 15/1952 90/18639 0.166666666666667 1.59144467213115 0.0465542260123922 0.413779169662591 GO:0004112 cyclic-nucleotide phosphodiesterase activity 6/1952 26/18639 0.230769230769231 2.20353877679697 0.0482036735456484 0.4225301315622 GO:0019865 immunoglobulin binding 6/1952 26/18639 0.230769230769231 2.20353877679697 0.0482036735456484 0.4225301315622 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 11/1952 61/18639 0.180327868852459 1.72189095673206 0.050222715654478 0.426805993651172 GO:0016530 metallochaperone activity 4/1952 14/18639 0.285714285714286 2.72819086651054 0.0509604725954834 0.426805993651172 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 4/1952 14/18639 0.285714285714286 2.72819086651054 0.0509604725954834 0.426805993651172 GO:0034236 protein kinase A catalytic subunit binding 4/1952 14/18639 0.285714285714286 2.72819086651054 0.0509604725954834 0.426805993651172 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 4/1952 14/18639 0.285714285714286 2.72819086651054 0.0509604725954834 0.426805993651172 GO:0042813 Wnt receptor activity 4/1952 14/18639 0.285714285714286 2.72819086651054 0.0509604725954834 0.426805993651172 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 5/1952 20/18639 0.25 2.38716700819672 0.051042101522406 0.426805993651172 GO:0005504 fatty acid binding 9/1952 47/18639 0.191489361702128 1.82846834670387 0.052443286456339 0.433481859279281 GO:0004532 RNA exonuclease activity 8/1952 40/18639 0.2 1.90973360655738 0.0525225856247122 0.433481859279281 GO:0051540 metal cluster binding 13/1952 77/18639 0.168831168831169 1.61211278475623 0.055908413410332 0.458448989964722 GO:0005044 scavenger receptor activity 6/1952 27/18639 0.222222222222222 2.1219262295082 0.0566931336491312 0.458961610624495 GO:0015252 proton channel activity 6/1952 27/18639 0.222222222222222 2.1219262295082 0.0566931336491312 0.458961610624495 GO:0000287 magnesium ion binding 32/1952 230/18639 0.139130434782609 1.32851033499644 0.0583305213539203 0.466939110212194 GO:0052866 phosphatidylinositol phosphate phosphatase activity 7/1952 34/18639 0.205882352941176 1.96590224204436 0.0590666930012239 0.466939110212194 GO:0033218 amide binding 34/1952 247/18639 0.137651821862348 1.31439155107188 0.0592374171641297 0.466939110212194 GO:0001530 lipopolysaccharide binding 8/1952 41/18639 0.195121951219512 1.86315473810476 0.0595154491379823 0.466939110212194 GO:0061650 ubiquitin-like protein conjugating enzyme activity 8/1952 41/18639 0.195121951219512 1.86315473810476 0.0595154491379823 0.466939110212194 GO:0001846 opsonin binding 5/1952 21/18639 0.238095238095238 2.27349238875878 0.0614272935136702 0.473176303368938 GO:0005123 death receptor binding 5/1952 21/18639 0.238095238095238 2.27349238875878 0.0614272935136702 0.473176303368938 GO:0008373 sialyltransferase activity 5/1952 21/18639 0.238095238095238 2.27349238875878 0.0614272935136702 0.473176303368938 GO:0015929 hexosaminidase activity 4/1952 15/18639 0.266666666666667 2.54631147540984 0.0639180006769974 0.489396258195564 GO:0051019 mitogen-activated protein kinase binding 6/1952 28/18639 0.214285714285714 2.0461431498829 0.0660226577007829 0.496455563408037 GO:0097718 disordered domain specific binding 6/1952 28/18639 0.214285714285714 2.0461431498829 0.0660226577007829 0.496455563408037 GO:1901681 sulfur compound binding 37/1952 275/18639 0.134545454545455 1.28472988077496 0.0669780389498026 0.496455563408037 GO:0016859 cis-trans isomerase activity 8/1952 42/18639 0.19047619047619 1.81879391100703 0.0670665854191603 0.496455563408037 GO:0000175 3'-5'-RNA exonuclease activity 7/1952 35/18639 0.2 1.90973360655738 0.0674458775183402 0.496455563408037 GO:0008081 phosphoric diester hydrolase activity 14/1952 87/18639 0.160919540229885 1.53656726964387 0.0678686535734505 0.496455563408037 GO:0004518 nuclease activity 29/1952 209/18639 0.138755980861244 1.32493479880775 0.0706127038552623 0.496455563408037 GO:0061134 peptidase regulator activity 31/1952 226/18639 0.13716814159292 1.3097730487451 0.0715976996523695 0.496455563408037 GO:0034062 5'-3' RNA polymerase activity 5/1952 22/18639 0.227272727272727 2.17015182563338 0.0729144762192544 0.496455563408037 GO:0061133 endopeptidase activator activity 5/1952 22/18639 0.227272727272727 2.17015182563338 0.0729144762192544 0.496455563408037 GO:0097747 RNA polymerase activity 5/1952 22/18639 0.227272727272727 2.17015182563338 0.0729144762192544 0.496455563408037 GO:0032813 tumor necrosis factor receptor superfamily binding 9/1952 50/18639 0.18 1.71876024590164 0.0729458981296949 0.496455563408037 GO:0019838 growth factor binding 20/1952 136/18639 0.147058823529412 1.40421588717454 0.0745396905553643 0.496455563408037 GO:0043539 protein serine/threonine kinase activator activity 12/1952 73/18639 0.164383561643836 1.56964406018415 0.0760568881916474 0.496455563408037 GO:0051861 glycolipid binding 6/1952 29/18639 0.206896551724138 1.97558648954211 0.0761927593306784 0.496455563408037 GO:0033192 calmodulin-dependent protein phosphatase activity 13/1952 81/18639 0.160493827160494 1.53250227686703 0.0778062536863447 0.496455563408037 GO:0140791 histone H2AXS140 phosphatase activity 13/1952 81/18639 0.160493827160494 1.53250227686703 0.0778062536863447 0.496455563408037 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 13/1952 81/18639 0.160493827160494 1.53250227686703 0.0778062536863447 0.496455563408037 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 13/1952 81/18639 0.160493827160494 1.53250227686703 0.0778062536863447 0.496455563408037 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 13/1952 81/18639 0.160493827160494 1.53250227686703 0.0778062536863447 0.496455563408037 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 13/1952 81/18639 0.160493827160494 1.53250227686703 0.0778062536863447 0.496455563408037 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 13/1952 81/18639 0.160493827160494 1.53250227686703 0.0778062536863447 0.496455563408037 GO:1990439 MAP kinase serine/threonine phosphatase activity 13/1952 81/18639 0.160493827160494 1.53250227686703 0.0778062536863447 0.496455563408037 GO:0017070 U6 snRNA binding 4/1952 16/18639 0.25 2.38716700819672 0.0784207752076652 0.496455563408037 GO:0034450 ubiquitin-ubiquitin ligase activity 4/1952 16/18639 0.25 2.38716700819672 0.0784207752076652 0.496455563408037 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 3/1952 10/18639 0.3 2.86460040983607 0.0785110686428131 0.496455563408037 GO:0008641 ubiquitin-like modifier activating enzyme activity 3/1952 10/18639 0.3 2.86460040983607 0.0785110686428131 0.496455563408037 GO:0015203 polyamine transmembrane transporter activity 3/1952 10/18639 0.3 2.86460040983607 0.0785110686428131 0.496455563408037 GO:0015279 store-operated calcium channel activity 3/1952 10/18639 0.3 2.86460040983607 0.0785110686428131 0.496455563408037 GO:0016175 superoxide-generating NAD(P)H oxidase activity 3/1952 10/18639 0.3 2.86460040983607 0.0785110686428131 0.496455563408037 GO:0033204 ribonuclease P RNA binding 3/1952 10/18639 0.3 2.86460040983607 0.0785110686428131 0.496455563408037 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 3/1952 10/18639 0.3 2.86460040983607 0.0785110686428131 0.496455563408037 GO:0043422 protein kinase B binding 3/1952 10/18639 0.3 2.86460040983607 0.0785110686428131 0.496455563408037 GO:0047429 nucleoside triphosphate diphosphatase activity 3/1952 10/18639 0.3 2.86460040983607 0.0785110686428131 0.496455563408037 GO:0097177 mitochondrial ribosome binding 3/1952 10/18639 0.3 2.86460040983607 0.0785110686428131 0.496455563408037 GO:0016922 nuclear receptor binding 20/1952 137/18639 0.145985401459854 1.39396613617327 0.0790854296023743 0.497611787250583 GO:0016830 carbon-carbon lyase activity 9/1952 51/18639 0.176470588235294 1.68505906460945 0.0807408828029866 0.505525428781261 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 13/1952 82/18639 0.158536585365854 1.51381322471012 0.0840323311574621 0.521000453176265 GO:0033549 MAP kinase phosphatase activity 13/1952 82/18639 0.158536585365854 1.51381322471012 0.0840323311574621 0.521000453176265 GO:0004725 protein tyrosine phosphatase activity 15/1952 98/18639 0.153061224489796 1.46153082134493 0.0854518378553265 0.524352216552148 GO:0042626 ATPase-coupled transmembrane transporter activity 15/1952 98/18639 0.153061224489796 1.46153082134493 0.0854518378553265 0.524352216552148 GO:0030295 protein kinase activator activity 20/1952 139/18639 0.143884892086331 1.37390906946574 0.088720862258573 0.524352216552148 GO:0070851 growth factor receptor binding 20/1952 139/18639 0.143884892086331 1.37390906946574 0.088720862258573 0.524352216552148 GO:0031072 heat shock protein binding 19/1952 131/18639 0.145038167938931 1.38492131773245 0.0896179253612423 0.524352216552148 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 13/1952 83/18639 0.156626506024096 1.49557451115939 0.090563656528737 0.524352216552148 GO:0035401 histone H3Y41 kinase activity 17/1952 115/18639 0.147826086956522 1.41154223093371 0.0909647650592921 0.524352216552148 GO:0140801 histone H2AXY142 kinase activity 17/1952 115/18639 0.147826086956522 1.41154223093371 0.0909647650592921 0.524352216552148 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 14/1952 91/18639 0.153846153846154 1.46902585119798 0.0912158462767098 0.524352216552148 GO:0019209 kinase activator activity 21/1952 148/18639 0.141891891891892 1.35487857221976 0.0926148411346502 0.524352216552148 GO:0004549 tRNA-specific ribonuclease activity 4/1952 17/18639 0.235294117647059 2.24674541947927 0.0944032462000369 0.524352216552148 GO:0004659 prenyltransferase activity 4/1952 17/18639 0.235294117647059 2.24674541947927 0.0944032462000369 0.524352216552148 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 4/1952 17/18639 0.235294117647059 2.24674541947927 0.0944032462000369 0.524352216552148 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 4/1952 17/18639 0.235294117647059 2.24674541947927 0.0944032462000369 0.524352216552148 GO:0008429 phosphatidylethanolamine binding 4/1952 17/18639 0.235294117647059 2.24674541947927 0.0944032462000369 0.524352216552148 GO:0015278 intracellularly gated calcium channel activity 4/1952 17/18639 0.235294117647059 2.24674541947927 0.0944032462000369 0.524352216552148 GO:0017110 nucleoside diphosphate phosphatase activity 4/1952 17/18639 0.235294117647059 2.24674541947927 0.0944032462000369 0.524352216552148 GO:0019198 transmembrane receptor protein phosphatase activity 4/1952 17/18639 0.235294117647059 2.24674541947927 0.0944032462000369 0.524352216552148 GO:0048038 quinone binding 4/1952 17/18639 0.235294117647059 2.24674541947927 0.0944032462000369 0.524352216552148 GO:0070403 NAD+ binding 4/1952 17/18639 0.235294117647059 2.24674541947927 0.0944032462000369 0.524352216552148 GO:0005126 cytokine receptor binding 36/1952 275/18639 0.130909090909091 1.25000745156483 0.0946198429640975 0.524352216552148 GO:0051536 iron-sulfur cluster binding 12/1952 76/18639 0.157894736842105 1.50768442622951 0.0965367444146065 0.524352216552148 GO:0098631 cell adhesion mediator activity 12/1952 76/18639 0.157894736842105 1.50768442622951 0.0965367444146065 0.524352216552148 GO:0017018 myosin phosphatase activity 13/1952 84/18639 0.154761904761905 1.47777005269321 0.097401030262028 0.524352216552148 GO:0051117 ATPase binding 13/1952 84/18639 0.154761904761905 1.47777005269321 0.097401030262028 0.524352216552148 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 5/1952 24/18639 0.208333333333333 1.98930584016393 0.0991126333516784 0.524352216552148 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 5/1952 24/18639 0.208333333333333 1.98930584016393 0.0991126333516784 0.524352216552148 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 5/1952 24/18639 0.208333333333333 1.98930584016393 0.0991126333516784 0.524352216552148 GO:0008503 benzodiazepine receptor activity 3/1952 11/18639 0.272727272727273 2.60418219076006 0.0998373221129976 0.524352216552148 GO:0010854 adenylate cyclase regulator activity 3/1952 11/18639 0.272727272727273 2.60418219076006 0.0998373221129976 0.524352216552148 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 3/1952 11/18639 0.272727272727273 2.60418219076006 0.0998373221129976 0.524352216552148 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 3/1952 11/18639 0.272727272727273 2.60418219076006 0.0998373221129976 0.524352216552148 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 3/1952 11/18639 0.272727272727273 2.60418219076006 0.0998373221129976 0.524352216552148 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 3/1952 11/18639 0.272727272727273 2.60418219076006 0.0998373221129976 0.524352216552148 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 3/1952 11/18639 0.272727272727273 2.60418219076006 0.0998373221129976 0.524352216552148 GO:0045294 alpha-catenin binding 3/1952 11/18639 0.272727272727273 2.60418219076006 0.0998373221129976 0.524352216552148 GO:0140031 phosphorylation-dependent protein binding 3/1952 11/18639 0.272727272727273 2.60418219076006 0.0998373221129976 0.524352216552148 GO:0015026 coreceptor activity 10/1952 61/18639 0.163934426229508 1.56535541521096 0.100904069263467 0.527773958987103 GO:0017069 snRNA binding 9/1952 54/18639 0.166666666666667 1.59144467213115 0.107021060092942 0.557474456467744 GO:0071813 lipoprotein particle binding 6/1952 32/18639 0.1875 1.79037525614754 0.111643673225052 0.570573775568142 GO:0071814 protein-lipid complex binding 6/1952 32/18639 0.1875 1.79037525614754 0.111643673225052 0.570573775568142 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 4/1952 18/18639 0.222222222222222 2.1219262295082 0.111780385614844 0.570573775568142 GO:0030228 lipoprotein particle receptor activity 4/1952 18/18639 0.222222222222222 2.1219262295082 0.111780385614844 0.570573775568142 GO:0070628 proteasome binding 4/1952 18/18639 0.222222222222222 2.1219262295082 0.111780385614844 0.570573775568142 GO:0000030 mannosyltransferase activity 5/1952 25/18639 0.2 1.90973360655738 0.113754239288383 0.573736659267994 GO:0001848 complement binding 5/1952 25/18639 0.2 1.90973360655738 0.113754239288383 0.573736659267994 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 5/1952 25/18639 0.2 1.90973360655738 0.113754239288383 0.573736659267994 GO:0051020 GTPase binding 40/1952 315/18639 0.126984126984127 1.21252927400468 0.115207654839431 0.578770471545123 GO:0098632 cell-cell adhesion mediator activity 9/1952 55/18639 0.163636363636364 1.56250931445604 0.116734098672207 0.584130076426674 GO:0004526 ribonuclease P activity 3/1952 12/18639 0.25 2.38716700819672 0.123175584692157 0.590777992995212 GO:0004875 complement receptor activity 3/1952 12/18639 0.25 2.38716700819672 0.123175584692157 0.590777992995212 GO:0005095 GTPase inhibitor activity 3/1952 12/18639 0.25 2.38716700819672 0.123175584692157 0.590777992995212 GO:0045295 gamma-catenin binding 3/1952 12/18639 0.25 2.38716700819672 0.123175584692157 0.590777992995212 GO:0070008 serine-type exopeptidase activity 3/1952 12/18639 0.25 2.38716700819672 0.123175584692157 0.590777992995212 GO:0097371 MDM2/MDM4 family protein binding 3/1952 12/18639 0.25 2.38716700819672 0.123175584692157 0.590777992995212 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 3/1952 12/18639 0.25 2.38716700819672 0.123175584692157 0.590777992995212 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 3/1952 12/18639 0.25 2.38716700819672 0.123175584692157 0.590777992995212 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 3/1952 12/18639 0.25 2.38716700819672 0.123175584692157 0.590777992995212 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 3/1952 12/18639 0.25 2.38716700819672 0.123175584692157 0.590777992995212 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 3/1952 12/18639 0.25 2.38716700819672 0.123175584692157 0.590777992995212 GO:0038187 pattern recognition receptor activity 8/1952 48/18639 0.166666666666667 1.59144467213115 0.12414132945248 0.59317154035377 GO:0140311 protein sequestering activity 6/1952 33/18639 0.181818181818182 1.73612146050671 0.125039916844199 0.595227469322012 GO:0048306 calcium-dependent protein binding 12/1952 80/18639 0.15 1.43230020491803 0.128541296666622 0.606710287496275 GO:0034237 protein kinase A regulatory subunit binding 5/1952 26/18639 0.192307692307692 1.83628231399748 0.129361516846177 0.606710287496275 GO:0043548 phosphatidylinositol 3-kinase binding 5/1952 26/18639 0.192307692307692 1.83628231399748 0.129361516846177 0.606710287496275 GO:0050681 nuclear androgen receptor binding 5/1952 26/18639 0.192307692307692 1.83628231399748 0.129361516846177 0.606710287496275 GO:0042277 peptide binding 32/1952 249/18639 0.1285140562249 1.22713806043848 0.130439596104926 0.607340142097836 GO:0043395 heparan sulfate proteoglycan binding 4/1952 19/18639 0.210526315789474 2.01024590163934 0.130451501803862 0.607340142097836 GO:0035091 phosphatidylinositol binding 36/1952 284/18639 0.126760563380282 1.21039453936735 0.131506067620211 0.608781568809823 GO:0042169 SH2 domain binding 7/1952 41/18639 0.170731707317073 1.63026039584166 0.131719064848703 0.608781568809823 GO:0060590 ATPase regulator activity 8/1952 49/18639 0.163265306122449 1.55896620943459 0.135557428416283 0.623209935247368 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 17/1952 122/18639 0.139344262295082 1.33055210292932 0.13582152011292 0.623209935247368 GO:0140030 modification-dependent protein binding 23/1952 173/18639 0.132947976878613 1.2694760968445 0.138051181639221 0.629928446036642 GO:0120013 lipid transfer activity 10/1952 65/18639 0.153846153846154 1.46902585119798 0.138276975959263 0.629928446036642 GO:0004713 protein tyrosine kinase activity 19/1952 140/18639 0.135714285714286 1.29589066159251 0.144310270702642 0.649749028504628 GO:0004364 glutathione transferase activity 5/1952 27/18639 0.185185185185185 1.7682718579235 0.145877058481869 0.649749028504628 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 5/1952 27/18639 0.185185185185185 1.7682718579235 0.145877058481869 0.649749028504628 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 5/1952 27/18639 0.185185185185185 1.7682718579235 0.145877058481869 0.649749028504628 GO:0017124 SH3 domain binding 16/1952 115/18639 0.139130434782609 1.32851033499644 0.14589594272928 0.649749028504628 GO:0005172 vascular endothelial growth factor receptor binding 3/1952 13/18639 0.230769230769231 2.20353877679697 0.148251155205619 0.649749028504628 GO:0005338 nucleotide-sugar transmembrane transporter activity 3/1952 13/18639 0.230769230769231 2.20353877679697 0.148251155205619 0.649749028504628 GO:0005542 folic acid binding 3/1952 13/18639 0.230769230769231 2.20353877679697 0.148251155205619 0.649749028504628 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 3/1952 13/18639 0.230769230769231 2.20353877679697 0.148251155205619 0.649749028504628 GO:0070700 BMP receptor binding 3/1952 13/18639 0.230769230769231 2.20353877679697 0.148251155205619 0.649749028504628 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 3/1952 13/18639 0.230769230769231 2.20353877679697 0.148251155205619 0.649749028504628 GO:0001614 purinergic nucleotide receptor activity 4/1952 20/18639 0.2 1.90973360655738 0.150303851874227 0.652000668027789 GO:0016502 nucleotide receptor activity 4/1952 20/18639 0.2 1.90973360655738 0.150303851874227 0.652000668027789 GO:0061608 nuclear import signal receptor activity 4/1952 20/18639 0.2 1.90973360655738 0.150303851874227 0.652000668027789 GO:0005096 GTPase activator activity 34/1952 271/18639 0.125461254612546 1.19798787127216 0.153179351335095 0.662214134513283 GO:0061631 ubiquitin conjugating enzyme activity 6/1952 35/18639 0.171428571428571 1.63691451990632 0.154017965629629 0.663582489204266 GO:0005496 steroid binding 15/1952 108/18639 0.138888888888889 1.32620389344262 0.156893108333485 0.673686286121147 GO:0008375 acetylglucosaminyltransferase activity 7/1952 43/18639 0.162790697674419 1.5544343309188 0.158157387466925 0.676828415725461 GO:0003743 translation initiation factor activity 8/1952 51/18639 0.156862745098039 1.49783027965284 0.159900653046956 0.677445766742271 GO:0005048 signal sequence binding 8/1952 51/18639 0.156862745098039 1.49783027965284 0.159900653046956 0.677445766742271 GO:0030544 Hsp70 protein binding 8/1952 51/18639 0.156862745098039 1.49783027965284 0.159900653046956 0.677445766742271 GO:0055106 ubiquitin-protein transferase regulator activity 6/1952 36/18639 0.166666666666667 1.59144467213115 0.169521275065856 0.71202470096801 GO:0031267 small GTPase binding 35/1952 283/18639 0.123674911660777 1.18093067543301 0.169963780088358 0.71202470096801 GO:0072542 protein phosphatase activator activity 4/1952 21/18639 0.19047619047619 1.81879391100703 0.171215983253181 0.71202470096801 GO:0098531 ligand-modulated transcription factor activity 9/1952 60/18639 0.15 1.43230020491803 0.172040894912424 0.71202470096801 GO:0016790 thiolester hydrolase activity 7/1952 44/18639 0.159090909090909 1.51910627794337 0.172213751499803 0.71202470096801 GO:0005545 1-phosphatidylinositol binding 3/1952 14/18639 0.214285714285714 2.0461431498829 0.174784977735656 0.71202470096801 GO:0008474 palmitoyl-(protein) hydrolase activity 3/1952 14/18639 0.214285714285714 2.0461431498829 0.174784977735656 0.71202470096801 GO:0031404 chloride ion binding 3/1952 14/18639 0.214285714285714 2.0461431498829 0.174784977735656 0.71202470096801 GO:0042043 neurexin family protein binding 3/1952 14/18639 0.214285714285714 2.0461431498829 0.174784977735656 0.71202470096801 GO:0044548 S100 protein binding 3/1952 14/18639 0.214285714285714 2.0461431498829 0.174784977735656 0.71202470096801 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 3/1952 14/18639 0.214285714285714 2.0461431498829 0.174784977735656 0.71202470096801 GO:0098599 palmitoyl hydrolase activity 3/1952 14/18639 0.214285714285714 2.0461431498829 0.174784977735656 0.71202470096801 GO:0016779 nucleotidyltransferase activity 18/1952 136/18639 0.132352941176471 1.26379429845709 0.178080066812657 0.723019570520912 GO:0140597 protein carrier chaperone 24/1952 188/18639 0.127659574468085 1.21897889780258 0.179172403886064 0.723019570520912 GO:0016757 glycosyltransferase activity 33/1952 267/18639 0.123595505617978 1.18017245349051 0.17919053085294 0.723019570520912 GO:0019905 syntaxin binding 9/1952 61/18639 0.147540983606557 1.40881987368987 0.184353037813205 0.741495921077795 GO:0017046 peptide hormone binding 8/1952 53/18639 0.150943396226415 1.44130838230745 0.186122700580285 0.7462522158913 GO:0008093 cytoskeletal anchor activity 4/1952 22/18639 0.181818181818182 1.73612146050671 0.193060762594054 0.766813216428258 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 4/1952 22/18639 0.181818181818182 1.73612146050671 0.193060762594054 0.766813216428258 GO:0140035 ubiquitin-like protein reader activity 4/1952 22/18639 0.181818181818182 1.73612146050671 0.193060762594054 0.766813216428258 GO:0051082 unfolded protein binding 16/1952 121/18639 0.132231404958678 1.26263378945942 0.196388266164415 0.777582140974042 GO:0001664 G protein-coupled receptor binding 36/1952 297/18639 0.121212121212121 1.15741430700447 0.19840153571214 0.777582140974042 GO:0015485 cholesterol binding 8/1952 54/18639 0.148148148148148 1.4146174863388 0.199879507621562 0.777582140974042 GO:0140463 chromatin-protein adaptor activity 8/1952 54/18639 0.148148148148148 1.4146174863388 0.199879507621562 0.777582140974042 GO:0008187 poly-pyrimidine tract binding 5/1952 30/18639 0.166666666666667 1.59144467213115 0.200205717623914 0.777582140974042 GO:0070566 adenylyltransferase activity 5/1952 30/18639 0.166666666666667 1.59144467213115 0.200205717623914 0.777582140974042 GO:0004559 alpha-mannosidase activity 3/1952 15/18639 0.2 1.90973360655738 0.202501722000321 0.777582140974042 GO:0005041 low-density lipoprotein particle receptor activity 3/1952 15/18639 0.2 1.90973360655738 0.202501722000321 0.777582140974042 GO:0005523 tropomyosin binding 3/1952 15/18639 0.2 1.90973360655738 0.202501722000321 0.777582140974042 GO:0050780 dopamine receptor binding 3/1952 15/18639 0.2 1.90973360655738 0.202501722000321 0.777582140974042 GO:0055105 ubiquitin-protein transferase inhibitor activity 3/1952 15/18639 0.2 1.90973360655738 0.202501722000321 0.777582140974042 GO:0005543 phospholipid binding 58/1952 497/18639 0.116700201207243 1.1143314806874 0.207274638300462 0.793512244818938 GO:0004602 glutathione peroxidase activity 4/1952 23/18639 0.173913043478261 1.66063791874555 0.215708070771148 0.811138928846535 GO:0005158 insulin receptor binding 4/1952 23/18639 0.173913043478261 1.66063791874555 0.215708070771148 0.811138928846535 GO:0017134 fibroblast growth factor binding 4/1952 23/18639 0.173913043478261 1.66063791874555 0.215708070771148 0.811138928846535 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 4/1952 23/18639 0.173913043478261 1.66063791874555 0.215708070771148 0.811138928846535 GO:0140103 catalytic activity, acting on a glycoprotein 4/1952 23/18639 0.173913043478261 1.66063791874555 0.215708070771148 0.811138928846535 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 4/1952 23/18639 0.173913043478261 1.66063791874555 0.215708070771148 0.811138928846535 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 17/1952 132/18639 0.128787878787879 1.22975270119225 0.217890970202995 0.813975203270104 GO:0042379 chemokine receptor binding 10/1952 72/18639 0.138888888888889 1.32620389344262 0.218209995570526 0.813975203270104 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 6/1952 39/18639 0.153846153846154 1.46902585119798 0.219538818765186 0.813975203270104 GO:0005164 tumor necrosis factor receptor binding 5/1952 31/18639 0.161290322580645 1.54010774722369 0.219664433297912 0.813975203270104 GO:0070325 lipoprotein particle receptor binding 5/1952 31/18639 0.161290322580645 1.54010774722369 0.219664433297912 0.813975203270104 GO:1901981 phosphatidylinositol phosphate binding 23/1952 185/18639 0.124324324324324 1.1871317013735 0.221256627727644 0.81749178442394 GO:0005085 guanyl-nucleotide exchange factor activity 28/1952 230/18639 0.121739130434783 1.16244654312188 0.225930308808451 0.83221978704112 GO:0043021 ribonucleoprotein complex binding 22/1952 177/18639 0.124293785310734 1.18684009447069 0.227833922987709 0.83221978704112 GO:0004521 RNA endonuclease activity 10/1952 73/18639 0.136986301369863 1.30803671682012 0.230920616876568 0.83221978704112 GO:0004708 MAP kinase kinase activity 3/1952 16/18639 0.1875 1.79037525614754 0.23113578664478 0.83221978704112 GO:0015923 mannosidase activity 3/1952 16/18639 0.1875 1.79037525614754 0.23113578664478 0.83221978704112 GO:0016722 oxidoreductase activity, acting on metal ions 3/1952 16/18639 0.1875 1.79037525614754 0.23113578664478 0.83221978704112 GO:0031435 mitogen-activated protein kinase kinase kinase binding 3/1952 16/18639 0.1875 1.79037525614754 0.23113578664478 0.83221978704112 GO:0043023 ribosomal large subunit binding 3/1952 16/18639 0.1875 1.79037525614754 0.23113578664478 0.83221978704112 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 3/1952 16/18639 0.1875 1.79037525614754 0.23113578664478 0.83221978704112 GO:0019843 rRNA binding 9/1952 65/18639 0.138461538461538 1.32212326607818 0.237156233885256 0.846249354156427 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 6/1952 40/18639 0.15 1.43230020491803 0.237211854147758 0.846249354156427 GO:0030331 nuclear estrogen receptor binding 6/1952 40/18639 0.15 1.43230020491803 0.237211854147758 0.846249354156427 GO:0001091 RNA polymerase II general transcription initiation factor binding 4/1952 24/18639 0.166666666666667 1.59144467213115 0.239027158255041 0.846249354156427 GO:0030215 semaphorin receptor binding 4/1952 24/18639 0.166666666666667 1.59144467213115 0.239027158255041 0.846249354156427 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 4/1952 24/18639 0.166666666666667 1.59144467213115 0.239027158255041 0.846249354156427 GO:0072341 modified amino acid binding 12/1952 91/18639 0.131868131868132 1.25916501531256 0.241765000542554 0.853564765804406 GO:0015932 nucleobase-containing compound transmembrane transporter activity 8/1952 57/18639 0.140350877192982 1.34016393442623 0.243410203192003 0.856992709853286 GO:0043177 organic acid binding 23/1952 189/18639 0.121693121693122 1.16200722092116 0.253271435148077 0.881613444027115 GO:0043178 alcohol binding 12/1952 92/18639 0.130434782608696 1.24547843905916 0.253591113672979 0.881613444027115 GO:0004519 endonuclease activity 16/1952 127/18639 0.125984251968504 1.20298179940622 0.25397467124305 0.881613444027115 GO:0030296 protein tyrosine kinase activator activity 5/1952 33/18639 0.151515151515152 1.44676788375559 0.260137627918643 0.881613444027115 GO:0004029 aldehyde dehydrogenase (NAD+) activity 3/1952 17/18639 0.176470588235294 1.68505906460945 0.260435616740082 0.881613444027115 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 3/1952 17/18639 0.176470588235294 1.68505906460945 0.260435616740082 0.881613444027115 GO:0016805 dipeptidase activity 3/1952 17/18639 0.176470588235294 1.68505906460945 0.260435616740082 0.881613444027115 GO:0030169 low-density lipoprotein particle binding 3/1952 17/18639 0.176470588235294 1.68505906460945 0.260435616740082 0.881613444027115 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 3/1952 17/18639 0.176470588235294 1.68505906460945 0.260435616740082 0.881613444027115 GO:0036041 long-chain fatty acid binding 3/1952 17/18639 0.176470588235294 1.68505906460945 0.260435616740082 0.881613444027115 GO:0038191 neuropilin binding 3/1952 17/18639 0.176470588235294 1.68505906460945 0.260435616740082 0.881613444027115 GO:0070402 NADPH binding 3/1952 17/18639 0.176470588235294 1.68505906460945 0.260435616740082 0.881613444027115 GO:0019902 phosphatase binding 23/1952 190/18639 0.121052631578947 1.15589139344262 0.261559772150974 0.881613444027115 GO:0003707 nuclear steroid receptor activity 4/1952 25/18639 0.16 1.5277868852459 0.262888666629643 0.881613444027115 GO:0015662 P-type ion transporter activity 4/1952 25/18639 0.16 1.5277868852459 0.262888666629643 0.881613444027115 GO:0019211 phosphatase activator activity 4/1952 25/18639 0.16 1.5277868852459 0.262888666629643 0.881613444027115 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 4/1952 25/18639 0.16 1.5277868852459 0.262888666629643 0.881613444027115 GO:0140358 P-type transmembrane transporter activity 4/1952 25/18639 0.16 1.5277868852459 0.262888666629643 0.881613444027115 GO:0042056 chemoattractant activity 6/1952 42/18639 0.142857142857143 1.36409543325527 0.27373746090976 0.88585040091213 GO:0048487 beta-tubulin binding 6/1952 42/18639 0.142857142857143 1.36409543325527 0.27373746090976 0.88585040091213 GO:0001786 phosphatidylserine binding 8/1952 59/18639 0.135593220338983 1.29473464851348 0.274020145200385 0.88585040091213 GO:0004879 nuclear receptor activity 8/1952 59/18639 0.135593220338983 1.29473464851348 0.274020145200385 0.88585040091213 GO:0032934 sterol binding 9/1952 68/18639 0.132352941176471 1.26379429845709 0.279861341242559 0.88585040091213 GO:0140223 general transcription initiation factor activity 9/1952 68/18639 0.132352941176471 1.26379429845709 0.279861341242559 0.88585040091213 GO:1990841 promoter-specific chromatin binding 9/1952 68/18639 0.132352941176471 1.26379429845709 0.279861341242559 0.88585040091213 GO:0016831 carboxy-lyase activity 5/1952 34/18639 0.147058823529412 1.40421588717454 0.280992902346147 0.88585040091213 GO:0001094 TFIID-class transcription factor complex binding 2/1952 10/18639 0.2 1.90973360655738 0.28224787679464 0.88585040091213 GO:0004382 GDP phosphatase activity 2/1952 10/18639 0.2 1.90973360655738 0.28224787679464 0.88585040091213 GO:0004445 inositol-polyphosphate 5-phosphatase activity 2/1952 10/18639 0.2 1.90973360655738 0.28224787679464 0.88585040091213 GO:0004862 cAMP-dependent protein kinase inhibitor activity 2/1952 10/18639 0.2 1.90973360655738 0.28224787679464 0.88585040091213 GO:0004983 neuropeptide Y receptor activity 2/1952 10/18639 0.2 1.90973360655738 0.28224787679464 0.88585040091213 GO:0005031 tumor necrosis factor receptor activity 2/1952 10/18639 0.2 1.90973360655738 0.28224787679464 0.88585040091213 GO:0005131 growth hormone receptor binding 2/1952 10/18639 0.2 1.90973360655738 0.28224787679464 0.88585040091213 GO:0005528 FK506 binding 2/1952 10/18639 0.2 1.90973360655738 0.28224787679464 0.88585040091213 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 2/1952 10/18639 0.2 1.90973360655738 0.28224787679464 0.88585040091213 GO:0015924 mannosyl-oligosaccharide mannosidase activity 2/1952 10/18639 0.2 1.90973360655738 0.28224787679464 0.88585040091213 GO:0016303 1-phosphatidylinositol-3-kinase activity 2/1952 10/18639 0.2 1.90973360655738 0.28224787679464 0.88585040091213 GO:0016783 sulfurtransferase activity 2/1952 10/18639 0.2 1.90973360655738 0.28224787679464 0.88585040091213 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 2/1952 10/18639 0.2 1.90973360655738 0.28224787679464 0.88585040091213 GO:0030957 Tat protein binding 2/1952 10/18639 0.2 1.90973360655738 0.28224787679464 0.88585040091213 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 2/1952 10/18639 0.2 1.90973360655738 0.28224787679464 0.88585040091213 GO:0070097 delta-catenin binding 2/1952 10/18639 0.2 1.90973360655738 0.28224787679464 0.88585040091213 GO:0071723 lipopeptide binding 2/1952 10/18639 0.2 1.90973360655738 0.28224787679464 0.88585040091213 GO:0005200 structural constituent of cytoskeleton 14/1952 112/18639 0.125 1.19358350409836 0.282273337820151 0.88585040091213 GO:0005160 transforming growth factor beta receptor binding 4/1952 26/18639 0.153846153846154 1.46902585119798 0.287166330226637 0.886542857280481 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 4/1952 26/18639 0.153846153846154 1.46902585119798 0.287166330226637 0.886542857280481 GO:0050750 low-density lipoprotein particle receptor binding 4/1952 26/18639 0.153846153846154 1.46902585119798 0.287166330226637 0.886542857280481 GO:0097602 cullin family protein binding 4/1952 26/18639 0.153846153846154 1.46902585119798 0.287166330226637 0.886542857280481 GO:0120014 phospholipid transfer activity 4/1952 26/18639 0.153846153846154 1.46902585119798 0.287166330226637 0.886542857280481 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 8/1952 60/18639 0.133333333333333 1.27315573770492 0.289709260629302 0.886542857280481 GO:0000400 four-way junction DNA binding 3/1952 18/18639 0.166666666666667 1.59144467213115 0.29016666296513 0.886542857280481 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 3/1952 18/18639 0.166666666666667 1.59144467213115 0.29016666296513 0.886542857280481 GO:0034185 apolipoprotein binding 3/1952 18/18639 0.166666666666667 1.59144467213115 0.29016666296513 0.886542857280481 GO:0035615 clathrin adaptor activity 3/1952 18/18639 0.166666666666667 1.59144467213115 0.29016666296513 0.886542857280481 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 3/1952 18/18639 0.166666666666667 1.59144467213115 0.29016666296513 0.886542857280481 GO:0004712 protein serine/threonine/tyrosine kinase activity 6/1952 43/18639 0.13953488372093 1.33237228364468 0.292480175522112 0.88933565332202 GO:0048156 tau protein binding 6/1952 43/18639 0.13953488372093 1.33237228364468 0.292480175522112 0.88933565332202 GO:0005080 protein kinase C binding 7/1952 52/18639 0.134615384615385 1.28539761979823 0.300217522530928 0.897719691868373 GO:0030159 signaling receptor complex adaptor activity 7/1952 52/18639 0.134615384615385 1.28539761979823 0.300217522530928 0.897719691868373 GO:0005154 epidermal growth factor receptor binding 5/1952 35/18639 0.142857142857143 1.36409543325527 0.3021553917989 0.897719691868373 GO:0043015 gamma-tubulin binding 5/1952 35/18639 0.142857142857143 1.36409543325527 0.3021553917989 0.897719691868373 GO:0140566 histone reader activity 5/1952 35/18639 0.142857142857143 1.36409543325527 0.3021553917989 0.897719691868373 GO:0016782 transferase activity, transferring sulphur-containing groups 9/1952 70/18639 0.128571428571429 1.22768588992974 0.309441734170422 0.897719691868373 GO:0004683 calcium/calmodulin-dependent protein kinase activity 4/1952 27/18639 0.148148148148148 1.4146174863388 0.311738377486597 0.897719691868373 GO:0005104 fibroblast growth factor receptor binding 4/1952 27/18639 0.148148148148148 1.4146174863388 0.311738377486597 0.897719691868373 GO:0008266 poly(U) RNA binding 4/1952 27/18639 0.148148148148148 1.4146174863388 0.311738377486597 0.897719691868373 GO:0046332 SMAD binding 10/1952 79/18639 0.126582278481013 1.20869215604897 0.312173852132739 0.897719691868373 GO:0031406 carboxylic acid binding 22/1952 187/18639 0.117647058823529 1.12337270973963 0.314131848175395 0.897719691868373 GO:0016251 RNA polymerase II general transcription initiation factor activity 7/1952 53/18639 0.132075471698113 1.26114483451902 0.317579778045155 0.897719691868373 GO:0051018 protein kinase A binding 7/1952 53/18639 0.132075471698113 1.26114483451902 0.317579778045155 0.897719691868373 GO:0140296 general transcription initiation factor binding 7/1952 53/18639 0.132075471698113 1.26114483451902 0.317579778045155 0.897719691868373 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 3/1952 19/18639 0.157894736842105 1.50768442622951 0.320113255682867 0.897719691868373 GO:0030506 ankyrin binding 3/1952 19/18639 0.157894736842105 1.50768442622951 0.320113255682867 0.897719691868373 GO:0070003 threonine-type peptidase activity 3/1952 19/18639 0.157894736842105 1.50768442622951 0.320113255682867 0.897719691868373 GO:0140036 ubiquitin-modified protein reader activity 3/1952 19/18639 0.157894736842105 1.50768442622951 0.320113255682867 0.897719691868373 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 2/1952 11/18639 0.181818181818182 1.73612146050671 0.322783555612782 0.897719691868373 GO:0004117 calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity 2/1952 11/18639 0.181818181818182 1.73612146050671 0.322783555612782 0.897719691868373 GO:0004143 ATP-dependent diacylglycerol kinase activity 2/1952 11/18639 0.181818181818182 1.73612146050671 0.322783555612782 0.897719691868373 GO:0005114 type II transforming growth factor beta receptor binding 2/1952 11/18639 0.181818181818182 1.73612146050671 0.322783555612782 0.897719691868373 GO:0008199 ferric iron binding 2/1952 11/18639 0.181818181818182 1.73612146050671 0.322783555612782 0.897719691868373 GO:0008432 JUN kinase binding 2/1952 11/18639 0.181818181818182 1.73612146050671 0.322783555612782 0.897719691868373 GO:0008526 phosphatidylinositol transfer activity 2/1952 11/18639 0.181818181818182 1.73612146050671 0.322783555612782 0.897719691868373 GO:0015217 ADP transmembrane transporter activity 2/1952 11/18639 0.181818181818182 1.73612146050671 0.322783555612782 0.897719691868373 GO:0016176 superoxide-generating NADPH oxidase activator activity 2/1952 11/18639 0.181818181818182 1.73612146050671 0.322783555612782 0.897719691868373 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 2/1952 11/18639 0.181818181818182 1.73612146050671 0.322783555612782 0.897719691868373 GO:0019107 myristoyltransferase activity 2/1952 11/18639 0.181818181818182 1.73612146050671 0.322783555612782 0.897719691868373 GO:0019215 intermediate filament binding 2/1952 11/18639 0.181818181818182 1.73612146050671 0.322783555612782 0.897719691868373 GO:0032794 GTPase activating protein binding 2/1952 11/18639 0.181818181818182 1.73612146050671 0.322783555612782 0.897719691868373 GO:0034713 type I transforming growth factor beta receptor binding 2/1952 11/18639 0.181818181818182 1.73612146050671 0.322783555612782 0.897719691868373 GO:0035252 UDP-xylosyltransferase activity 2/1952 11/18639 0.181818181818182 1.73612146050671 0.322783555612782 0.897719691868373 GO:0042285 xylosyltransferase activity 2/1952 11/18639 0.181818181818182 1.73612146050671 0.322783555612782 0.897719691868373 GO:0048101 calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity 2/1952 11/18639 0.181818181818182 1.73612146050671 0.322783555612782 0.897719691868373 GO:0048185 activin binding 2/1952 11/18639 0.181818181818182 1.73612146050671 0.322783555612782 0.897719691868373 GO:0070990 snRNP binding 2/1952 11/18639 0.181818181818182 1.73612146050671 0.322783555612782 0.897719691868373 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 2/1952 11/18639 0.181818181818182 1.73612146050671 0.322783555612782 0.897719691868373 GO:1990948 ubiquitin ligase inhibitor activity 2/1952 11/18639 0.181818181818182 1.73612146050671 0.322783555612782 0.897719691868373 GO:0030246 carbohydrate binding 32/1952 280/18639 0.114285714285714 1.09127634660422 0.326931832669063 0.907271526904759 GO:0051539 4 iron, 4 sulfur cluster binding 6/1952 45/18639 0.133333333333333 1.27315573770492 0.330651531617615 0.915594981886687 GO:0050661 NADP binding 7/1952 54/18639 0.12962962962963 1.23779030054645 0.335109605555052 0.920083864268545 GO:0008083 growth factor activity 19/1952 162/18639 0.117283950617284 1.11990551001821 0.336022789997497 0.920083864268545 GO:0046966 nuclear thyroid hormone receptor binding 4/1952 28/18639 0.142857142857143 1.36409543325527 0.336488655263433 0.920083864268545 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 4/1952 28/18639 0.142857142857143 1.36409543325527 0.336488655263433 0.920083864268545 GO:0019955 cytokine binding 17/1952 144/18639 0.118055555555556 1.12727330942623 0.338091002180685 0.920083864268545 GO:0019208 phosphatase regulator activity 14/1952 117/18639 0.11965811965812 1.14257566204288 0.340449173902078 0.920083864268545 GO:0030971 receptor tyrosine kinase binding 10/1952 81/18639 0.123456790123457 1.17884790528233 0.340661229702129 0.920083864268545 GO:0005506 iron ion binding 18/1952 154/18639 0.116883116883117 1.11607808175431 0.347480674566617 0.920083864268545 GO:0004180 carboxypeptidase activity 6/1952 46/18639 0.130434782608696 1.24547843905916 0.349972720884667 0.920083864268545 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 6/1952 46/18639 0.130434782608696 1.24547843905916 0.349972720884667 0.920083864268545 GO:0030291 protein serine/threonine kinase inhibitor activity 6/1952 46/18639 0.130434782608696 1.24547843905916 0.349972720884667 0.920083864268545 GO:0010851 cyclase regulator activity 3/1952 20/18639 0.15 1.43230020491803 0.350079621060863 0.920083864268545 GO:0016408 C-acyltransferase activity 3/1952 20/18639 0.15 1.43230020491803 0.350079621060863 0.920083864268545 GO:0016505 peptidase activator activity involved in apoptotic process 3/1952 20/18639 0.15 1.43230020491803 0.350079621060863 0.920083864268545 GO:0043024 ribosomal small subunit binding 3/1952 20/18639 0.15 1.43230020491803 0.350079621060863 0.920083864268545 GO:0140313 molecular sequestering activity 7/1952 55/18639 0.127272727272727 1.21528502235469 0.352766768373738 0.920083864268545 GO:0003785 actin monomer binding 4/1952 29/18639 0.137931034482759 1.31705765969474 0.361307501323658 0.920083864268545 GO:0004629 phospholipase C activity 4/1952 29/18639 0.137931034482759 1.31705765969474 0.361307501323658 0.920083864268545 GO:0016417 S-acyltransferase activity 4/1952 29/18639 0.137931034482759 1.31705765969474 0.361307501323658 0.920083864268545 GO:0043236 laminin binding 4/1952 29/18639 0.137931034482759 1.31705765969474 0.361307501323658 0.920083864268545 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 4/1952 29/18639 0.137931034482759 1.31705765969474 0.361307501323658 0.920083864268545 GO:0099604 ligand-gated calcium channel activity 4/1952 29/18639 0.137931034482759 1.31705765969474 0.361307501323658 0.920083864268545 GO:0000340 RNA 7-methylguanosine cap binding 2/1952 12/18639 0.166666666666667 1.59144467213115 0.362705149796908 0.920083864268545 GO:0000995 RNA polymerase III general transcription initiation factor activity 2/1952 12/18639 0.166666666666667 1.59144467213115 0.362705149796908 0.920083864268545 GO:0003995 acyl-CoA dehydrogenase activity 2/1952 12/18639 0.166666666666667 1.59144467213115 0.362705149796908 0.920083864268545 GO:0004032 aldose reductase (NADPH) activity 2/1952 12/18639 0.166666666666667 1.59144467213115 0.362705149796908 0.920083864268545 GO:0004859 phospholipase inhibitor activity 2/1952 12/18639 0.166666666666667 1.59144467213115 0.362705149796908 0.920083864268545 GO:0005165 neurotrophin receptor binding 2/1952 12/18639 0.166666666666667 1.59144467213115 0.362705149796908 0.920083864268545 GO:0005527 macrolide binding 2/1952 12/18639 0.166666666666667 1.59144467213115 0.362705149796908 0.920083864268545 GO:0008504 monoamine transmembrane transporter activity 2/1952 12/18639 0.166666666666667 1.59144467213115 0.362705149796908 0.920083864268545 GO:0008603 cAMP-dependent protein kinase regulator activity 2/1952 12/18639 0.166666666666667 1.59144467213115 0.362705149796908 0.920083864268545 GO:0015368 calcium:monoatomic cation antiporter activity 2/1952 12/18639 0.166666666666667 1.59144467213115 0.362705149796908 0.920083864268545 GO:0016208 AMP binding 2/1952 12/18639 0.166666666666667 1.59144467213115 0.362705149796908 0.920083864268545 GO:0016423 tRNA (guanine) methyltransferase activity 2/1952 12/18639 0.166666666666667 1.59144467213115 0.362705149796908 0.920083864268545 GO:0034452 dynactin binding 2/1952 12/18639 0.166666666666667 1.59144467213115 0.362705149796908 0.920083864268545 GO:0035497 cAMP response element binding 2/1952 12/18639 0.166666666666667 1.59144467213115 0.362705149796908 0.920083864268545 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 2/1952 12/18639 0.166666666666667 1.59144467213115 0.362705149796908 0.920083864268545 GO:0070410 co-SMAD binding 2/1952 12/18639 0.166666666666667 1.59144467213115 0.362705149796908 0.920083864268545 GO:0070679 inositol 1,4,5 trisphosphate binding 2/1952 12/18639 0.166666666666667 1.59144467213115 0.362705149796908 0.920083864268545 GO:0141221 histone deacetylase activity, hydrolytic mechanism 2/1952 12/18639 0.166666666666667 1.59144467213115 0.362705149796908 0.920083864268545 GO:1990459 transferrin receptor binding 2/1952 12/18639 0.166666666666667 1.59144467213115 0.362705149796908 0.920083864268545 GO:1990817 poly(A) RNA polymerase activity 2/1952 12/18639 0.166666666666667 1.59144467213115 0.362705149796908 0.920083864268545 GO:0140098 catalytic activity, acting on RNA 43/1952 387/18639 0.111111111111111 1.0609631147541 0.363400550639504 0.920083864268545 GO:0043531 ADP binding 5/1952 38/18639 0.131578947368421 1.25640368852459 0.366726834199035 0.92665965460631 GO:0001784 phosphotyrosine residue binding 6/1952 47/18639 0.127659574468085 1.21897889780258 0.369381326713922 0.928410093796993 GO:0005254 chloride channel activity 10/1952 83/18639 0.120481927710843 1.15044193166107 0.369564999491738 0.928410093796993 GO:0004857 enzyme inhibitor activity 46/1952 416/18639 0.110576923076923 1.05586233054855 0.370161076922932 0.928410093796993 GO:0003684 damaged DNA binding 9/1952 74/18639 0.121621621621622 1.16132449047408 0.370341398548447 0.928410093796993 GO:0061135 endopeptidase regulator activity 21/1952 184/18639 0.114130434782609 1.08979363417676 0.372209335086481 0.931256033257712 GO:0035591 signaling adaptor activity 15/1952 129/18639 0.116279069767442 1.11031023637057 0.374482268127235 0.935102087995513 GO:0009931 calcium-dependent protein serine/threonine kinase activity 3/1952 21/18639 0.142857142857143 1.36409543325527 0.379890227362143 0.943658029861719 GO:0140312 cargo adaptor activity 3/1952 21/18639 0.142857142857143 1.36409543325527 0.379890227362143 0.943658029861719 GO:0008238 exopeptidase activity 12/1952 102/18639 0.117647058823529 1.12337270973963 0.380425182641978 0.943658029861719 GO:0019207 kinase regulator activity 32/1952 287/18639 0.111498257839721 1.06465985034558 0.380878496710513 0.943658029861719 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 4/1952 30/18639 0.133333333333333 1.27315573770492 0.386092391123619 0.950383322503793 GO:0015215 nucleotide transmembrane transporter activity 4/1952 30/18639 0.133333333333333 1.27315573770492 0.386092391123619 0.950383322503793 GO:0033612 receptor serine/threonine kinase binding 4/1952 30/18639 0.133333333333333 1.27315573770492 0.386092391123619 0.950383322503793 GO:0016874 ligase activity 19/1952 167/18639 0.11377245508982 1.08637540492785 0.387008596302283 0.950383322503793 GO:0015108 chloride transmembrane transporter activity 14/1952 121/18639 0.115702479338843 1.104804565777 0.388616532024457 0.950383322503793 GO:0032266 phosphatidylinositol-3-phosphate binding 6/1952 48/18639 0.125 1.19358350409836 0.388827165776532 0.950383322503793 GO:0140693 molecular condensate scaffold activity 6/1952 48/18639 0.125 1.19358350409836 0.388827165776532 0.950383322503793 GO:0043022 ribosome binding 13/1952 112/18639 0.116071428571429 1.10832753951991 0.391106394658356 0.952530996194306 GO:0042562 hormone binding 11/1952 94/18639 0.117021276595745 1.1173973229857 0.396165866296178 0.952530996194306 GO:0004535 poly(A)-specific ribonuclease activity 2/1952 13/18639 0.153846153846154 1.46902585119798 0.401696785177142 0.952530996194306 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 2/1952 13/18639 0.153846153846154 1.46902585119798 0.401696785177142 0.952530996194306 GO:0004993 G protein-coupled serotonin receptor activity 2/1952 13/18639 0.153846153846154 1.46902585119798 0.401696785177142 0.952530996194306 GO:0005035 death receptor activity 2/1952 13/18639 0.153846153846154 1.46902585119798 0.401696785177142 0.952530996194306 GO:0015651 quaternary ammonium group transmembrane transporter activity 2/1952 13/18639 0.153846153846154 1.46902585119798 0.401696785177142 0.952530996194306 GO:0017154 semaphorin receptor activity 2/1952 13/18639 0.153846153846154 1.46902585119798 0.401696785177142 0.952530996194306 GO:0031432 titin binding 2/1952 13/18639 0.153846153846154 1.46902585119798 0.401696785177142 0.952530996194306 GO:0032396 inhibitory MHC class I receptor activity 2/1952 13/18639 0.153846153846154 1.46902585119798 0.401696785177142 0.952530996194306 GO:0035673 oligopeptide transmembrane transporter activity 2/1952 13/18639 0.153846153846154 1.46902585119798 0.401696785177142 0.952530996194306 GO:0046974 histone H3K9 methyltransferase activity 2/1952 13/18639 0.153846153846154 1.46902585119798 0.401696785177142 0.952530996194306 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 2/1952 13/18639 0.153846153846154 1.46902585119798 0.401696785177142 0.952530996194306 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 2/1952 13/18639 0.153846153846154 1.46902585119798 0.401696785177142 0.952530996194306 GO:0089720 caspase binding 2/1952 13/18639 0.153846153846154 1.46902585119798 0.401696785177142 0.952530996194306 GO:0140666 annealing activity 2/1952 13/18639 0.153846153846154 1.46902585119798 0.401696785177142 0.952530996194306 GO:0004407 histone deacetylase activity 3/1952 22/18639 0.136363636363636 1.30209109538003 0.409389616536052 0.96143866883399 GO:0016881 acid-amino acid ligase activity 3/1952 22/18639 0.136363636363636 1.30209109538003 0.409389616536052 0.96143866883399 GO:0033558 protein lysine deacetylase activity 3/1952 22/18639 0.136363636363636 1.30209109538003 0.409389616536052 0.96143866883399 GO:0033691 sialic acid binding 3/1952 22/18639 0.136363636363636 1.30209109538003 0.409389616536052 0.96143866883399 GO:0071949 FAD binding 5/1952 40/18639 0.125 1.19358350409836 0.409966455791882 0.96143866883399 GO:0008327 methyl-CpG binding 4/1952 31/18639 0.129032258064516 1.23208619777895 0.410748384875575 0.96143866883399 GO:0072349 modified amino acid transmembrane transporter activity 4/1952 31/18639 0.129032258064516 1.23208619777895 0.410748384875575 0.96143866883399 GO:0019887 protein kinase regulator activity 28/1952 255/18639 0.109803921568627 1.04848119575699 0.424929192473133 0.992803315502485 GO:0015605 organophosphate ester transmembrane transporter activity 6/1952 50/18639 0.12 1.14584016393443 0.427639686013192 0.995764881467325 GO:0001727 lipid kinase activity 5/1952 41/18639 0.121951219512195 1.16447171131547 0.431448417386128 0.995764881467325 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 5/1952 41/18639 0.121951219512195 1.16447171131547 0.431448417386128 0.995764881467325 GO:0008227 G protein-coupled amine receptor activity 5/1952 41/18639 0.121951219512195 1.16447171131547 0.431448417386128 0.995764881467325 GO:0016877 ligase activity, forming carbon-sulfur bonds 5/1952 41/18639 0.121951219512195 1.16447171131547 0.431448417386128 0.995764881467325 GO:0000149 SNARE binding 12/1952 106/18639 0.113207547169811 1.08098128673059 0.433354852276196 0.995764881467325 GO:0008013 beta-catenin binding 12/1952 106/18639 0.113207547169811 1.08098128673059 0.433354852276196 0.995764881467325 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4/1952 32/18639 0.125 1.19358350409836 0.435188400178394 0.995764881467325 GO:0051059 NF-kappaB binding 4/1952 32/18639 0.125 1.19358350409836 0.435188400178394 0.995764881467325 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 3/1952 23/18639 0.130434782608696 1.24547843905916 0.438441848400788 0.995764881467325 GO:0031681 G-protein beta-subunit binding 3/1952 23/18639 0.130434782608696 1.24547843905916 0.438441848400788 0.995764881467325 GO:0070577 lysine-acetylated histone binding 3/1952 23/18639 0.130434782608696 1.24547843905916 0.438441848400788 0.995764881467325 GO:0004705 JUN kinase activity 2/1952 14/18639 0.142857142857143 1.36409543325527 0.439515419750724 0.995764881467325 GO:0005347 ATP transmembrane transporter activity 2/1952 14/18639 0.142857142857143 1.36409543325527 0.439515419750724 0.995764881467325 GO:0015926 glucosidase activity 2/1952 14/18639 0.142857142857143 1.36409543325527 0.439515419750724 0.995764881467325 GO:0046030 inositol trisphosphate phosphatase activity 2/1952 14/18639 0.142857142857143 1.36409543325527 0.439515419750724 0.995764881467325 GO:0071933 Arp2/3 complex binding 2/1952 14/18639 0.142857142857143 1.36409543325527 0.439515419750724 0.995764881467325 GO:0001098 basal transcription machinery binding 7/1952 60/18639 0.116666666666667 1.1140112704918 0.441615998851179 0.996969688347865 GO:0001099 basal RNA polymerase II transcription machinery binding 7/1952 60/18639 0.116666666666667 1.1140112704918 0.441615998851179 0.996969688347865 GO:0019888 protein phosphatase regulator activity 12/1952 107/18639 0.11214953271028 1.07087865788264 0.446590933104032 1 GO:0033293 monocarboxylic acid binding 9/1952 79/18639 0.113924050632911 1.08782294044408 0.447633075962975 1 GO:0097110 scaffold protein binding 8/1952 70/18639 0.114285714285714 1.09127634660422 0.453163868962479 1 GO:0140713 histone chaperone activity 18/1952 164/18639 0.109756097560976 1.04802454018393 0.453730600241505 1 GO:1990782 protein tyrosine kinase binding 13/1952 117/18639 0.111111111111111 1.0609631147541 0.454529544817849 1 GO:0003727 single-stranded RNA binding 10/1952 89/18639 0.112359550561798 1.07288404862774 0.457093837167091 1 GO:0000049 tRNA binding 9/1952 80/18639 0.1125 1.07422515368852 0.463006386202687 1 GO:0004622 lysophospholipase activity 3/1952 24/18639 0.125 1.19358350409836 0.466929661278751 1 GO:0005540 hyaluronic acid binding 3/1952 24/18639 0.125 1.19358350409836 0.466929661278751 1 GO:0015295 solute:proton symporter activity 3/1952 24/18639 0.125 1.19358350409836 0.466929661278751 1 GO:0035035 histone acetyltransferase binding 3/1952 24/18639 0.125 1.19358350409836 0.466929661278751 1 GO:0048027 mRNA 5'-UTR binding 3/1952 24/18639 0.125 1.19358350409836 0.466929661278751 1 GO:0140033 acetylation-dependent protein binding 3/1952 24/18639 0.125 1.19358350409836 0.466929661278751 1 GO:0003714 transcription corepressor activity 22/1952 204/18639 0.107843137254902 1.02975831726133 0.475698195867806 1 GO:0004865 protein serine/threonine phosphatase inhibitor activity 2/1952 15/18639 0.133333333333333 1.27315573770492 0.475979065558478 1 GO:0010181 FMN binding 2/1952 15/18639 0.133333333333333 1.27315573770492 0.475979065558478 1 GO:0016846 carbon-sulfur lyase activity 2/1952 15/18639 0.133333333333333 1.27315573770492 0.475979065558478 1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 2/1952 15/18639 0.133333333333333 1.27315573770492 0.475979065558478 1 GO:0017081 chloride channel regulator activity 2/1952 15/18639 0.133333333333333 1.27315573770492 0.475979065558478 1 GO:0031386 protein tag activity 2/1952 15/18639 0.133333333333333 1.27315573770492 0.475979065558478 1 GO:0042809 nuclear vitamin D receptor binding 2/1952 15/18639 0.133333333333333 1.27315573770492 0.475979065558478 1 GO:0120283 protein serine/threonine kinase binding 2/1952 15/18639 0.133333333333333 1.27315573770492 0.475979065558478 1 GO:0140776 protein-containing complex destabilizing activity 2/1952 15/18639 0.133333333333333 1.27315573770492 0.475979065558478 1 GO:0141047 molecular tag activity 2/1952 15/18639 0.133333333333333 1.27315573770492 0.475979065558478 1 GO:0141050 histone H3K deacetylase activity 2/1952 15/18639 0.133333333333333 1.27315573770492 0.475979065558478 1 GO:0141051 histone H4K deacetylase activity 2/1952 15/18639 0.133333333333333 1.27315573770492 0.475979065558478 1 GO:0001618 virus receptor activity 9/1952 81/18639 0.111111111111111 1.0609631147541 0.478299530765257 1 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 4/1952 34/18639 0.117647058823529 1.12337270973963 0.483112058541459 1 GO:0090482 vitamin transmembrane transporter activity 4/1952 34/18639 0.117647058823529 1.12337270973963 0.483112058541459 1 GO:0005125 cytokine activity 25/1952 234/18639 0.106837606837607 1.02015684110971 0.489449896143953 1 GO:0140101 catalytic activity, acting on a tRNA 15/1952 139/18639 0.107913669064748 1.0304318020993 0.491789863679241 1 GO:0140272 exogenous protein binding 9/1952 82/18639 0.109756097560976 1.04802454018393 0.493491991683397 1 GO:0001223 transcription coactivator binding 5/1952 44/18639 0.113636363636364 1.08507591281669 0.494668283649373 1 GO:0005251 delayed rectifier potassium channel activity 3/1952 25/18639 0.12 1.14584016393443 0.494753433276356 1 GO:0008139 nuclear localization sequence binding 3/1952 25/18639 0.12 1.14584016393443 0.494753433276356 1 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 3/1952 25/18639 0.12 1.14584016393443 0.494753433276356 1 GO:0019706 protein-cysteine S-palmitoyltransferase activity 3/1952 25/18639 0.12 1.14584016393443 0.494753433276356 1 GO:0019707 protein-cysteine S-acyltransferase activity 3/1952 25/18639 0.12 1.14584016393443 0.494753433276356 1 GO:0016229 steroid dehydrogenase activity 4/1952 35/18639 0.114285714285714 1.09127634660422 0.50646130586308 1 GO:0008135 translation factor activity, RNA binding 9/1952 83/18639 0.108433734939759 1.03539773849496 0.508564193436436 1 GO:0030165 PDZ domain binding 9/1952 83/18639 0.108433734939759 1.03539773849496 0.508564193436436 1 GO:0000062 fatty-acyl-CoA binding 2/1952 16/18639 0.125 1.19358350409836 0.510956676831863 1 GO:0004707 MAP kinase activity 2/1952 16/18639 0.125 1.19358350409836 0.510956676831863 1 GO:0005024 transforming growth factor beta receptor activity 2/1952 16/18639 0.125 1.19358350409836 0.510956676831863 1 GO:0005159 insulin-like growth factor receptor binding 2/1952 16/18639 0.125 1.19358350409836 0.510956676831863 1 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/1952 16/18639 0.125 1.19358350409836 0.510956676831863 1 GO:0005521 lamin binding 2/1952 16/18639 0.125 1.19358350409836 0.510956676831863 1 GO:0008296 3'-5'-DNA exonuclease activity 2/1952 16/18639 0.125 1.19358350409836 0.510956676831863 1 GO:0055102 lipase inhibitor activity 2/1952 16/18639 0.125 1.19358350409836 0.510956676831863 1 GO:0097027 ubiquitin-protein transferase activator activity 2/1952 16/18639 0.125 1.19358350409836 0.510956676831863 1 GO:0099507 ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 2/1952 16/18639 0.125 1.19358350409836 0.510956676831863 1 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 2/1952 16/18639 0.125 1.19358350409836 0.510956676831863 1 GO:0140328 floppase activity 2/1952 16/18639 0.125 1.19358350409836 0.510956676831863 1 GO:0004536 DNA nuclease activity 7/1952 64/18639 0.109375 1.04438556608607 0.511276267082723 1 GO:0051213 dioxygenase activity 10/1952 93/18639 0.10752688172043 1.02673849814913 0.514562038623295 1 GO:0003713 transcription coactivator activity 27/1952 256/18639 0.10546875 1.00708608158299 0.514874488229113 1 GO:0004715 non-membrane spanning protein tyrosine kinase activity 5/1952 45/18639 0.111111111111111 1.0609631147541 0.515170377653342 1 GO:0046915 transition metal ion transmembrane transporter activity 5/1952 45/18639 0.111111111111111 1.0609631147541 0.515170377653342 1 GO:0035064 methylated histone binding 8/1952 74/18639 0.108108108108108 1.03228843597696 0.517765133116891 1 GO:0042393 histone binding 26/1952 247/18639 0.105263157894737 1.00512295081967 0.519930924492911 1 GO:0004529 DNA exonuclease activity 3/1952 26/18639 0.115384615384615 1.10176938839849 0.521830011935016 1 GO:0005112 Notch binding 3/1952 26/18639 0.115384615384615 1.10176938839849 0.521830011935016 1 GO:0008066 glutamate receptor activity 3/1952 26/18639 0.115384615384615 1.10176938839849 0.521830011935016 1 GO:0008198 ferrous iron binding 3/1952 26/18639 0.115384615384615 1.10176938839849 0.521830011935016 1 GO:0015216 purine nucleotide transmembrane transporter activity 3/1952 26/18639 0.115384615384615 1.10176938839849 0.521830011935016 1 GO:0030247 polysaccharide binding 3/1952 26/18639 0.115384615384615 1.10176938839849 0.521830011935016 1 GO:0030507 spectrin binding 3/1952 26/18639 0.115384615384615 1.10176938839849 0.521830011935016 1 GO:0052742 phosphatidylinositol kinase activity 3/1952 26/18639 0.115384615384615 1.10176938839849 0.521830011935016 1 GO:0070412 R-SMAD binding 3/1952 26/18639 0.115384615384615 1.10176938839849 0.521830011935016 1 GO:0180051 translation factor activity 9/1952 84/18639 0.107142857142857 1.02307157494145 0.523497542923416 1 GO:0004869 cysteine-type endopeptidase inhibitor activity 4/1952 36/18639 0.111111111111111 1.0609631147541 0.529325470186968 1 GO:0005484 SNAP receptor activity 4/1952 36/18639 0.111111111111111 1.0609631147541 0.529325470186968 1 GO:0016409 palmitoyltransferase activity 4/1952 36/18639 0.111111111111111 1.0609631147541 0.529325470186968 1 GO:0044183 protein folding chaperone 8/1952 75/18639 0.106666666666667 1.01852459016393 0.533524718549354 1 GO:0005092 GDP-dissociation inhibitor activity 2/1952 17/18639 0.117647058823529 1.12337270973963 0.544359484844101 1 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/1952 17/18639 0.117647058823529 1.12337270973963 0.544359484844101 1 GO:0015347 sodium-independent organic anion transmembrane transporter activity 2/1952 17/18639 0.117647058823529 1.12337270973963 0.544359484844101 1 GO:0032183 SUMO binding 2/1952 17/18639 0.117647058823529 1.12337270973963 0.544359484844101 1 GO:0045125 bioactive lipid receptor activity 2/1952 17/18639 0.117647058823529 1.12337270973963 0.544359484844101 1 GO:0045236 CXCR chemokine receptor binding 2/1952 17/18639 0.117647058823529 1.12337270973963 0.544359484844101 1 GO:0070492 oligosaccharide binding 2/1952 17/18639 0.117647058823529 1.12337270973963 0.544359484844101 1 GO:1901567 fatty acid derivative binding 2/1952 17/18639 0.117647058823529 1.12337270973963 0.544359484844101 1 GO:0023026 MHC class II protein complex binding 3/1952 27/18639 0.111111111111111 1.0609631147541 0.548091466241068 1 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 3/1952 27/18639 0.111111111111111 1.0609631147541 0.548091466241068 1 GO:0140034 methylation-dependent protein binding 8/1952 76/18639 0.105263157894737 1.00512295081967 0.549086402803481 1 GO:0019903 protein phosphatase binding 15/1952 144/18639 0.104166666666667 0.994652920081967 0.549137646983701 1 GO:0001221 transcription coregulator binding 12/1952 115/18639 0.104347826086957 0.996382751247327 0.550359850155314 1 GO:0022829 wide pore channel activity 4/1952 37/18639 0.108108108108108 1.03228843597696 0.55165633510989 1 GO:0030551 cyclic nucleotide binding 4/1952 37/18639 0.108108108108108 1.03228843597696 0.55165633510989 1 GO:0050660 flavin adenine dinucleotide binding 9/1952 86/18639 0.104651162790698 0.999279212733511 0.552878410898646 1 GO:0043495 protein-membrane adaptor activity 5/1952 47/18639 0.106382978723404 1.01581574816882 0.555070612719091 1 GO:0140359 ABC-type transporter activity 5/1952 47/18639 0.106382978723404 1.01581574816882 0.555070612719091 1 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 7/1952 67/18639 0.104477611940299 0.997622033276242 0.561448610348606 1 GO:0030594 neurotransmitter receptor activity 10/1952 97/18639 0.103092783505155 0.984398766266689 0.570046439769613 1 GO:0003712 transcription coregulator activity 51/1952 495/18639 0.103030303030303 0.9838021609538 0.571950859018036 1 GO:0045499 chemorepellent activity 3/1952 28/18639 0.107142857142857 1.02307157494145 0.573483803558385 1 GO:0000900 mRNA regulatory element binding translation repressor activity 2/1952 18/18639 0.111111111111111 1.0609631147541 0.576133587578972 1 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/1952 18/18639 0.111111111111111 1.0609631147541 0.576133587578972 1 GO:0004970 glutamate-gated receptor activity 2/1952 18/18639 0.111111111111111 1.0609631147541 0.576133587578972 1 GO:0008409 5'-3' exonuclease activity 2/1952 18/18639 0.111111111111111 1.0609631147541 0.576133587578972 1 GO:0008525 phosphatidylcholine transporter activity 2/1952 18/18639 0.111111111111111 1.0609631147541 0.576133587578972 1 GO:0016854 racemase and epimerase activity 2/1952 18/18639 0.111111111111111 1.0609631147541 0.576133587578972 1 GO:0017075 syntaxin-1 binding 2/1952 18/18639 0.111111111111111 1.0609631147541 0.576133587578972 1 GO:0022851 GABA-gated chloride ion channel activity 2/1952 18/18639 0.111111111111111 1.0609631147541 0.576133587578972 1 GO:0032393 MHC class I receptor activity 2/1952 18/18639 0.111111111111111 1.0609631147541 0.576133587578972 1 GO:0050811 GABA receptor binding 2/1952 18/18639 0.111111111111111 1.0609631147541 0.576133587578972 1 GO:0070064 proline-rich region binding 2/1952 18/18639 0.111111111111111 1.0609631147541 0.576133587578972 1 GO:0098641 cadherin binding involved in cell-cell adhesion 2/1952 18/18639 0.111111111111111 1.0609631147541 0.576133587578972 1 GO:0015459 potassium channel regulator activity 6/1952 59/18639 0.101694915254237 0.971050986385107 0.593103809617527 1 GO:0031593 polyubiquitin modification-dependent protein binding 6/1952 59/18639 0.101694915254237 0.971050986385107 0.593103809617527 1 GO:0036002 pre-mRNA binding 6/1952 59/18639 0.101694915254237 0.971050986385107 0.593103809617527 1 GO:0045309 protein phosphorylated amino acid binding 6/1952 59/18639 0.101694915254237 0.971050986385107 0.593103809617527 1 GO:0070063 RNA polymerase binding 6/1952 59/18639 0.101694915254237 0.971050986385107 0.593103809617527 1 GO:0001222 transcription corepressor binding 5/1952 49/18639 0.102040816326531 0.974353880896621 0.593280707509179 1 GO:0016758 hexosyltransferase activity 20/1952 197/18639 0.101522842639594 0.969407922110344 0.593292347881767 1 GO:0004181 metallocarboxypeptidase activity 3/1952 29/18639 0.103448275862069 0.987793244771057 0.597965684585468 1 GO:0004890 GABA-A receptor activity 2/1952 19/18639 0.105263157894737 1.00512295081967 0.606253626625572 1 GO:0005229 intracellularly calcium-gated chloride channel activity 2/1952 19/18639 0.105263157894737 1.00512295081967 0.606253626625572 1 GO:0005346 purine ribonucleotide transmembrane transporter activity 2/1952 19/18639 0.105263157894737 1.00512295081967 0.606253626625572 1 GO:0015245 fatty acid transmembrane transporter activity 2/1952 19/18639 0.105263157894737 1.00512295081967 0.606253626625572 1 GO:0022821 solute:potassium antiporter activity 2/1952 19/18639 0.105263157894737 1.00512295081967 0.606253626625572 1 GO:0031420 alkali metal ion binding 2/1952 19/18639 0.105263157894737 1.00512295081967 0.606253626625572 1 GO:0042577 lipid phosphatase activity 2/1952 19/18639 0.105263157894737 1.00512295081967 0.606253626625572 1 GO:0042834 peptidoglycan binding 2/1952 19/18639 0.105263157894737 1.00512295081967 0.606253626625572 1 GO:0046624 sphingolipid transporter activity 2/1952 19/18639 0.105263157894737 1.00512295081967 0.606253626625572 1 GO:0050145 nucleoside monophosphate kinase activity 2/1952 19/18639 0.105263157894737 1.00512295081967 0.606253626625572 1 GO:0120227 acyl-CoA binding 2/1952 19/18639 0.105263157894737 1.00512295081967 0.606253626625572 1 GO:0141147 intracellularly calcium-gated channel activity 2/1952 19/18639 0.105263157894737 1.00512295081967 0.606253626625572 1 GO:1990380 K48-linked deubiquitinase activity 2/1952 19/18639 0.105263157894737 1.00512295081967 0.606253626625572 1 GO:0030414 peptidase inhibitor activity 17/1952 169/18639 0.100591715976331 0.960516902706373 0.607270858248989 1 GO:0019210 kinase inhibitor activity 9/1952 90/18639 0.1 0.954866803278689 0.609270929300659 1 GO:0048020 CCR chemokine receptor binding 5/1952 50/18639 0.1 0.954866803278689 0.611685265453178 1 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 4/1952 40/18639 0.1 0.954866803278689 0.615070667132426 1 GO:0050997 quaternary ammonium group binding 4/1952 40/18639 0.1 0.954866803278689 0.615070667132426 1 GO:0071855 neuropeptide receptor binding 4/1952 40/18639 0.1 0.954866803278689 0.615070667132426 1 GO:0140662 ATP-dependent protein folding chaperone 4/1952 40/18639 0.1 0.954866803278689 0.615070667132426 1 GO:0141108 transporter regulator activity 17/1952 170/18639 0.1 0.954866803278689 0.617255329158198 1 GO:0016829 lyase activity 20/1952 200/18639 0.1 0.954866803278689 0.621130160117146 1 GO:0140996 histone H3 kinase activity 36/1952 357/18639 0.100840336134454 0.962890894062543 0.621494441245311 1 GO:0001968 fibronectin binding 3/1952 30/18639 0.1 0.954866803278689 0.621507161636785 1 GO:0008106 alcohol dehydrogenase (NADP+) activity 3/1952 30/18639 0.1 0.954866803278689 0.621507161636785 1 GO:0031210 phosphatidylcholine binding 3/1952 30/18639 0.1 0.954866803278689 0.621507161636785 1 GO:1902936 phosphatidylinositol bisphosphate binding 11/1952 111/18639 0.0990990990990991 0.946264399645547 0.6228464918906 1 GO:0004866 endopeptidase inhibitor activity 16/1952 161/18639 0.0993788819875776 0.948935953568883 0.626179691690597 1 GO:0000339 RNA cap binding 2/1952 20/18639 0.1 0.954866803278689 0.634717405021651 1 GO:0005326 neurotransmitter transmembrane transporter activity 2/1952 20/18639 0.1 0.954866803278689 0.634717405021651 1 GO:0031418 L-ascorbic acid binding 2/1952 20/18639 0.1 0.954866803278689 0.634717405021651 1 GO:0042288 MHC class I protein binding 2/1952 20/18639 0.1 0.954866803278689 0.634717405021651 1 GO:0052745 inositol phosphate phosphatase activity 2/1952 20/18639 0.1 0.954866803278689 0.634717405021651 1 GO:0140664 ATP-dependent DNA damage sensor activity 2/1952 20/18639 0.1 0.954866803278689 0.634717405021651 1 GO:0140939 histone H4 methyltransferase activity 2/1952 20/18639 0.1 0.954866803278689 0.634717405021651 1 GO:0042287 MHC protein binding 4/1952 41/18639 0.0975609756097561 0.931577369052379 0.634921721159053 1 GO:0140674 ATP-dependent histone chaperone activity 15/1952 152/18639 0.0986842105263158 0.942302766393443 0.635669883564524 1 GO:0016755 aminoacyltransferase activity 50/1952 496/18639 0.100806451612903 0.962567342014807 0.63571430828935 1 GO:0035173 histone kinase activity 36/1952 360/18639 0.1 0.954866803278689 0.641914701621148 1 GO:0005184 neuropeptide hormone activity 3/1952 31/18639 0.0967741935483871 0.924064648334215 0.644088459146915 1 GO:0005310 dicarboxylic acid transmembrane transporter activity 3/1952 31/18639 0.0967741935483871 0.924064648334215 0.644088459146915 1 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 5/1952 52/18639 0.0961538461538462 0.918141156998739 0.646993186085059 1 GO:0005253 monoatomic anion channel activity 10/1952 103/18639 0.0970873786407767 0.927055148814261 0.647702295817335 1 GO:0031625 ubiquitin protein ligase binding 30/1952 302/18639 0.0993377483443709 0.948543182064922 0.648954337247169 1 GO:0044389 ubiquitin-like protein ligase binding 32/1952 322/18639 0.0993788819875776 0.948935953568883 0.651042714016132 1 GO:0004520 DNA endonuclease activity 4/1952 42/18639 0.0952380952380952 0.909396955503513 0.654096564565074 1 GO:0019894 kinesin binding 4/1952 42/18639 0.0952380952380952 0.909396955503513 0.654096564565074 1 GO:0031492 nucleosomal DNA binding 4/1952 42/18639 0.0952380952380952 0.909396955503513 0.654096564565074 1 GO:0043175 RNA polymerase core enzyme binding 4/1952 42/18639 0.0952380952380952 0.909396955503513 0.654096564565074 1 GO:0051879 Hsp90 protein binding 4/1952 42/18639 0.0952380952380952 0.909396955503513 0.654096564565074 1 GO:0008237 metallopeptidase activity 18/1952 184/18639 0.0978260869565217 0.934108829294369 0.656168488081489 1 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 2/1952 21/18639 0.0952380952380952 0.909396955503513 0.661541318459494 1 GO:0005248 voltage-gated sodium channel activity 2/1952 21/18639 0.0952380952380952 0.909396955503513 0.661541318459494 1 GO:0010314 phosphatidylinositol-5-phosphate binding 2/1952 21/18639 0.0952380952380952 0.909396955503513 0.661541318459494 1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/1952 21/18639 0.0952380952380952 0.909396955503513 0.661541318459494 1 GO:1904047 S-adenosyl-L-methionine binding 2/1952 21/18639 0.0952380952380952 0.909396955503513 0.661541318459494 1 GO:0016410 N-acyltransferase activity 9/1952 94/18639 0.0957446808510638 0.914234173351936 0.661849719936026 1 GO:0004864 protein phosphatase inhibitor activity 5/1952 53/18639 0.0943396226415094 0.900817738942159 0.663866961240651 1 GO:0008146 sulfotransferase activity 5/1952 53/18639 0.0943396226415094 0.900817738942159 0.663866961240651 1 GO:0034212 protein N-acetyltransferase activity 5/1952 53/18639 0.0943396226415094 0.900817738942159 0.663866961240651 1 GO:1901505 carbohydrate derivative transmembrane transporter activity 5/1952 53/18639 0.0943396226415094 0.900817738942159 0.663866961240651 1 GO:0004860 protein kinase inhibitor activity 8/1952 84/18639 0.0952380952380952 0.909396955503513 0.664539584163177 1 GO:0015103 inorganic anion transmembrane transporter activity 16/1952 165/18639 0.096969696969697 0.925931445603577 0.665525863649431 1 GO:0015106 bicarbonate transmembrane transporter activity 3/1952 32/18639 0.09375 0.895187628073771 0.665698810074693 1 GO:0042910 xenobiotic transmembrane transporter activity 3/1952 32/18639 0.09375 0.895187628073771 0.665698810074693 1 GO:0070717 poly-purine tract binding 3/1952 32/18639 0.09375 0.895187628073771 0.665698810074693 1 GO:0160041 neuropeptide activity 3/1952 32/18639 0.09375 0.895187628073771 0.665698810074693 1 GO:0141003 histone H2AX kinase activity 35/1952 354/18639 0.0988700564971751 0.94407734787441 0.667481064706933 1 GO:0048029 monosaccharide binding 7/1952 74/18639 0.0945945945945946 0.903252381479841 0.66819017350439 1 GO:0000182 rDNA binding 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0003796 lysozyme activity 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0004935 adrenergic receptor activity 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0004955 prostaglandin receptor activity 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0005345 purine nucleobase transmembrane transporter activity 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0005381 iron ion transmembrane transporter activity 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0005522 profilin binding 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0008519 ammonium channel activity 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0015643 toxic substance binding 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0016427 tRNA (cytidine) methyltransferase activity 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0019531 oxalate transmembrane transporter activity 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0019911 structural constituent of myelin sheath 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0031434 mitogen-activated protein kinase kinase binding 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0031996 thioesterase binding 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0032356 oxidized DNA binding 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0035256 G protein-coupled glutamate receptor binding 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0035374 chondroitin sulfate binding 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0043208 glycosphingolipid binding 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0043225 ATPase-coupled inorganic anion transmembrane transporter activity 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0045322 unmethylated CpG binding 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0050308 sugar-phosphatase activity 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0051378 serotonin binding 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0070513 death domain binding 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0070739 protein-glutamic acid ligase activity 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0070740 tubulin-glutamic acid ligase activity 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0140940 histone H2A methyltransferase activity 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:1905394 retromer complex binding 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:1990259 histone H2AQ104 methyltransferase activity 1/1952 10/18639 0.1 0.954866803278689 0.669300240045887 1 GO:0003779 actin binding 44/1952 443/18639 0.0993227990970655 0.948400436665063 0.669524768791701 1 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 4/1952 43/18639 0.0930232558139535 0.888248189096454 0.672583365786676 1 GO:0003925 G protein activity 5/1952 54/18639 0.0925925925925926 0.884135928961749 0.680206257084501 1 GO:0003725 double-stranded RNA binding 7/1952 75/18639 0.0933333333333333 0.891209016393443 0.682052793867408 1 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 16/1952 167/18639 0.0958083832335329 0.914842446255031 0.68433277535292 1 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 3/1952 33/18639 0.0909090909090909 0.868060730253353 0.686335357653843 1 GO:0019239 deaminase activity 3/1952 33/18639 0.0909090909090909 0.868060730253353 0.686335357653843 1 GO:0042923 neuropeptide binding 3/1952 33/18639 0.0909090909090909 0.868060730253353 0.686335357653843 1 GO:0071889 14-3-3 protein binding 3/1952 33/18639 0.0909090909090909 0.868060730253353 0.686335357653843 1 GO:0005243 gap junction channel activity 2/1952 22/18639 0.0909090909090909 0.868060730253353 0.686756488651838 1 GO:0008649 rRNA methyltransferase activity 2/1952 22/18639 0.0909090909090909 0.868060730253353 0.686756488651838 1 GO:0015377 chloride:monoatomic cation symporter activity 2/1952 22/18639 0.0909090909090909 0.868060730253353 0.686756488651838 1 GO:0050321 tau-protein kinase activity 2/1952 22/18639 0.0909090909090909 0.868060730253353 0.686756488651838 1 GO:0070034 telomerase RNA binding 2/1952 22/18639 0.0909090909090909 0.868060730253353 0.686756488651838 1 GO:0019783 ubiquitin-like protein peptidase activity 12/1952 127/18639 0.094488188976378 0.902236349554666 0.689739934084926 1 GO:0001046 core promoter sequence-specific DNA binding 4/1952 44/18639 0.0909090909090909 0.868060730253353 0.690374874000407 1 GO:0019205 nucleobase-containing compound kinase activity 4/1952 44/18639 0.0909090909090909 0.868060730253353 0.690374874000407 1 GO:0001217 DNA-binding transcription repressor activity 27/1952 278/18639 0.0971223021582734 0.927388621889374 0.690402983172935 1 GO:0016247 channel regulator activity 16/1952 168/18639 0.0952380952380952 0.909396955503513 0.693507398504758 1 GO:0140658 ATP-dependent chromatin remodeler activity 15/1952 158/18639 0.0949367088607595 0.90651911703673 0.694692161204982 1 GO:0051015 actin filament binding 20/1952 209/18639 0.0956937799043062 0.913748137108793 0.698932183177042 1 GO:0046982 protein heterodimerization activity 36/1952 369/18639 0.0975609756097561 0.931577369052379 0.699953869889901 1 GO:0001653 peptide receptor activity 12/1952 128/18639 0.09375 0.895187628073771 0.700111630144039 1 GO:0008235 metalloexopeptidase activity 6/1952 66/18639 0.0909090909090909 0.868060730253353 0.702234138931717 1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0000099 sulfur amino acid transmembrane transporter activity 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0002162 dystroglycan binding 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0003953 NAD+ nucleosidase activity 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0004954 prostanoid receptor activity 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0005225 volume-sensitive anion channel activity 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0005536 D-glucose binding 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0008046 axon guidance receptor activity 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0008271 secondary active sulfate transmembrane transporter activity 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0015173 aromatic amino acid transmembrane transporter activity 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0015205 nucleobase transmembrane transporter activity 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0019203 carbohydrate phosphatase activity 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0019206 nucleoside kinase activity 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0032050 clathrin heavy chain binding 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0032404 mismatch repair complex binding 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0034056 estrogen response element binding 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0042608 T cell receptor binding 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0050998 nitric-oxide synthase binding 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0070697 activin receptor binding 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0099508 voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0140537 transcription regulator activator activity 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0180030 inositol phosphate kinase activity 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:1900750 oligopeptide binding 1/1952 11/18639 0.0909090909090909 0.868060730253353 0.703951908489197 1 GO:0019787 ubiquitin-like protein transferase activity 47/1952 479/18639 0.0981210855949896 0.936925673363223 0.70562170744435 1 GO:0008509 monoatomic anion transmembrane transporter activity 14/1952 149/18639 0.0939597315436242 0.897190284959842 0.705690328754386 1 GO:0008175 tRNA methyltransferase activity 3/1952 34/18639 0.0882352941176471 0.842529532304725 0.706002128535687 1 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 3/1952 34/18639 0.0882352941176471 0.842529532304725 0.706002128535687 1 GO:0008170 N-methyltransferase activity 9/1952 98/18639 0.0918367346938776 0.876918492806959 0.710061954068574 1 GO:0000295 adenine nucleotide transmembrane transporter activity 2/1952 23/18639 0.0869565217391304 0.830318959372773 0.710405502009081 1 GO:0003887 DNA-directed DNA polymerase activity 2/1952 23/18639 0.0869565217391304 0.830318959372773 0.710405502009081 1 GO:0004022 alcohol dehydrogenase (NAD+) activity 2/1952 23/18639 0.0869565217391304 0.830318959372773 0.710405502009081 1 GO:0008171 O-methyltransferase activity 2/1952 23/18639 0.0869565217391304 0.830318959372773 0.710405502009081 1 GO:0016493 C-C chemokine receptor activity 2/1952 23/18639 0.0869565217391304 0.830318959372773 0.710405502009081 1 GO:0016917 GABA receptor activity 2/1952 23/18639 0.0869565217391304 0.830318959372773 0.710405502009081 1 GO:0042171 lysophosphatidic acid acyltransferase activity 2/1952 23/18639 0.0869565217391304 0.830318959372773 0.710405502009081 1 GO:0071617 lysophospholipid acyltransferase activity 2/1952 23/18639 0.0869565217391304 0.830318959372773 0.710405502009081 1 GO:0140102 catalytic activity, acting on a rRNA 2/1952 23/18639 0.0869565217391304 0.830318959372773 0.710405502009081 1 GO:0019212 phosphatase inhibitor activity 5/1952 56/18639 0.0892857142857143 0.852559645784543 0.711255923048037 1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 5/1952 56/18639 0.0892857142857143 0.852559645784543 0.711255923048037 1 GO:0008173 RNA methyltransferase activity 6/1952 67/18639 0.0895522388059701 0.855104599951064 0.716081895841531 1 GO:0004620 phospholipase activity 10/1952 109/18639 0.0917431192660551 0.876024590163934 0.716936529603886 1 GO:0016298 lipase activity 12/1952 130/18639 0.0923076923076923 0.881415510718789 0.720209957736685 1 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 12/1952 130/18639 0.0923076923076923 0.881415510718789 0.720209957736685 1 GO:0030276 clathrin binding 4/1952 46/18639 0.0869565217391304 0.830318959372773 0.72386338247509 1 GO:0000510 H3-H4 histone complex chaperone activity 14/1952 151/18639 0.0927152317880795 0.885306969927261 0.724218681590378 1 GO:0140584 chromatin extrusion motor activity 14/1952 151/18639 0.0927152317880795 0.885306969927261 0.724218681590378 1 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 14/1952 151/18639 0.0927152317880795 0.885306969927261 0.724218681590378 1 GO:0140849 ATP-dependent H2AZ histone chaperone activity 14/1952 151/18639 0.0927152317880795 0.885306969927261 0.724218681590378 1 GO:0015149 hexose transmembrane transporter activity 2/1952 24/18639 0.0833333333333333 0.795722336065574 0.732539669348202 1 GO:0019957 C-C chemokine binding 2/1952 24/18639 0.0833333333333333 0.795722336065574 0.732539669348202 1 GO:0030552 cAMP binding 2/1952 24/18639 0.0833333333333333 0.795722336065574 0.732539669348202 1 GO:0050431 transforming growth factor beta binding 2/1952 24/18639 0.0833333333333333 0.795722336065574 0.732539669348202 1 GO:0050699 WW domain binding 2/1952 24/18639 0.0833333333333333 0.795722336065574 0.732539669348202 1 GO:0055056 D-glucose transmembrane transporter activity 2/1952 24/18639 0.0833333333333333 0.795722336065574 0.732539669348202 1 GO:0070300 phosphatidic acid binding 2/1952 24/18639 0.0833333333333333 0.795722336065574 0.732539669348202 1 GO:0070840 dynein complex binding 2/1952 24/18639 0.0833333333333333 0.795722336065574 0.732539669348202 1 GO:0140612 DNA damage sensor activity 2/1952 24/18639 0.0833333333333333 0.795722336065574 0.732539669348202 1 GO:0015616 DNA translocase activity 14/1952 152/18639 0.0921052631578947 0.879482581967213 0.733201892984305 1 GO:0004000 adenosine deaminase activity 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0004126 cytidine deaminase activity 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0004300 enoyl-CoA hydratase activity 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0005025 transforming growth factor beta receptor activity, type I 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0005026 transforming growth factor beta receptor activity, type II 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0005078 MAP-kinase scaffold activity 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0005247 voltage-gated chloride channel activity 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0008179 adenylate cyclase binding 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0010853 cyclase activator activity 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0015132 prostaglandin transmembrane transporter activity 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0015269 calcium-activated potassium channel activity 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0016273 arginine N-methyltransferase activity 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0016274 protein-arginine N-methyltransferase activity 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0016361 activin receptor activity, type I 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0016362 activin receptor activity, type II 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0017002 activin receptor activity 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0031543 peptidyl-proline dioxygenase activity 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0035197 siRNA binding 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0035251 UDP-glucosyltransferase activity 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0035259 nuclear glucocorticoid receptor binding 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0036009 protein-glutamine N-methyltransferase activity 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0042301 phosphate ion binding 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0140900 chloride:bicarbonate antiporter activity 1/1952 12/18639 0.0833333333333333 0.795722336065574 0.734974341097587 1 GO:0061733 protein-lysine-acetyltransferase activity 4/1952 47/18639 0.0851063829787234 0.812652598535054 0.739565035475648 1 GO:0099095 ligand-gated monoatomic anion channel activity 4/1952 47/18639 0.0851063829787234 0.812652598535054 0.739565035475648 1 GO:0140938 histone H3 methyltransferase activity 4/1952 47/18639 0.0851063829787234 0.812652598535054 0.739565035475648 1 GO:0061775 cohesin loader activity 14/1952 153/18639 0.0915032679738562 0.873734329797493 0.741995473047928 1 GO:0002039 p53 binding 6/1952 69/18639 0.0869565217391304 0.830318959372773 0.742422937579475 1 GO:0098960 postsynaptic neurotransmitter receptor activity 6/1952 69/18639 0.0869565217391304 0.830318959372773 0.742422937579475 1 GO:0004033 aldo-keto reductase (NADPH) activity 3/1952 36/18639 0.0833333333333333 0.795722336065574 0.742471227067996 1 GO:0045505 dynein intermediate chain binding 3/1952 36/18639 0.0833333333333333 0.795722336065574 0.742471227067996 1 GO:0008528 G protein-coupled peptide receptor activity 11/1952 122/18639 0.0901639344262295 0.860945478366031 0.743376808450103 1 GO:0004709 MAP kinase kinase kinase activity 2/1952 25/18639 0.08 0.763893442622951 0.753216733354449 1 GO:0005537 D-mannose binding 2/1952 25/18639 0.08 0.763893442622951 0.753216733354449 1 GO:0015271 outward rectifier potassium channel activity 2/1952 25/18639 0.08 0.763893442622951 0.753216733354449 1 GO:0015296 monoatomic anion:monoatomic cation symporter activity 2/1952 25/18639 0.08 0.763893442622951 0.753216733354449 1 GO:0047617 fatty acyl-CoA hydrolase activity 2/1952 25/18639 0.08 0.763893442622951 0.753216733354449 1 GO:0070888 E-box binding 5/1952 59/18639 0.0847457627118644 0.809209155320922 0.753729474403166 1 GO:0016879 ligase activity, forming carbon-nitrogen bonds 4/1952 48/18639 0.0833333333333333 0.795722336065574 0.754579925420298 1 GO:0004842 ubiquitin-protein transferase activity 43/1952 449/18639 0.0957683741648107 0.914460412939501 0.756675683176813 1 GO:0019213 deacetylase activity 3/1952 37/18639 0.0810810810810811 0.77421632698272 0.759307835181947 1 GO:0023023 MHC protein complex binding 3/1952 37/18639 0.0810810810810811 0.77421632698272 0.759307835181947 1 GO:0042805 actinin binding 3/1952 37/18639 0.0810810810810811 0.77421632698272 0.759307835181947 1 GO:0005516 calmodulin binding 19/1952 207/18639 0.0917874396135266 0.876447790449038 0.761595734112771 1 GO:0002161 aminoacyl-tRNA editing activity 1/1952 13/18639 0.0769230769230769 0.734512925598991 0.762747470757624 1 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 1/1952 13/18639 0.0769230769230769 0.734512925598991 0.762747470757624 1 GO:0008417 fucosyltransferase activity 1/1952 13/18639 0.0769230769230769 0.734512925598991 0.762747470757624 1 GO:0009982 pseudouridine synthase activity 1/1952 13/18639 0.0769230769230769 0.734512925598991 0.762747470757624 1 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/1952 13/18639 0.0769230769230769 0.734512925598991 0.762747470757624 1 GO:0019104 DNA N-glycosylase activity 1/1952 13/18639 0.0769230769230769 0.734512925598991 0.762747470757624 1 GO:0030955 potassium ion binding 1/1952 13/18639 0.0769230769230769 0.734512925598991 0.762747470757624 1 GO:0031994 insulin-like growth factor I binding 1/1952 13/18639 0.0769230769230769 0.734512925598991 0.762747470757624 1 GO:0043560 insulin receptor substrate binding 1/1952 13/18639 0.0769230769230769 0.734512925598991 0.762747470757624 1 GO:0070123 transforming growth factor beta receptor activity, type III 1/1952 13/18639 0.0769230769230769 0.734512925598991 0.762747470757624 1 GO:0071714 icosanoid transmembrane transporter activity 1/1952 13/18639 0.0769230769230769 0.734512925598991 0.762747470757624 1 GO:1901338 catecholamine binding 1/1952 13/18639 0.0769230769230769 0.734512925598991 0.762747470757624 1 GO:0015297 antiporter activity 12/1952 135/18639 0.0888888888888889 0.848770491803279 0.766591504346373 1 GO:0140299 molecular sensor activity 6/1952 71/18639 0.0845070422535211 0.806929692911568 0.766960680220856 1 GO:0035254 glutamate receptor binding 4/1952 49/18639 0.0816326530612245 0.779483104717297 0.768917633679064 1 GO:0051219 phosphoprotein binding 8/1952 93/18639 0.0860215053763441 0.821390798519302 0.770757743351061 1 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 21/1952 229/18639 0.091703056768559 0.87564204667478 0.771631054075264 1 GO:0001637 G protein-coupled chemoattractant receptor activity 2/1952 26/18639 0.0769230769230769 0.734512925598991 0.772498960139402 1 GO:0004435 phosphatidylinositol phospholipase C activity 2/1952 26/18639 0.0769230769230769 0.734512925598991 0.772498960139402 1 GO:0004950 chemokine receptor activity 2/1952 26/18639 0.0769230769230769 0.734512925598991 0.772498960139402 1 GO:0008143 poly(A) binding 2/1952 26/18639 0.0769230769230769 0.734512925598991 0.772498960139402 1 GO:0015145 monosaccharide transmembrane transporter activity 2/1952 26/18639 0.0769230769230769 0.734512925598991 0.772498960139402 1 GO:0016289 acyl-CoA hydrolase activity 2/1952 26/18639 0.0769230769230769 0.734512925598991 0.772498960139402 1 GO:0042887 amide transmembrane transporter activity 3/1952 38/18639 0.0789473684210526 0.753842213114754 0.77524169988482 1 GO:0101005 deubiquitinase activity 10/1952 115/18639 0.0869565217391304 0.830318959372773 0.776731765761804 1 GO:0004674 protein serine/threonine kinase activity 41/1952 433/18639 0.0946882217090069 0.904146395714232 0.776834137154126 1 GO:0016836 hydro-lyase activity 5/1952 61/18639 0.0819672131147541 0.782677707605482 0.779339749786695 1 GO:0008094 ATP-dependent activity, acting on DNA 19/1952 210/18639 0.0904761904761905 0.863927107728337 0.782530971395541 1 GO:0004065 arylsulfatase activity 1/1952 14/18639 0.0714285714285714 0.682047716627635 0.787611474681232 1 GO:0008174 mRNA methyltransferase activity 1/1952 14/18639 0.0714285714285714 0.682047716627635 0.787611474681232 1 GO:0008191 metalloendopeptidase inhibitor activity 1/1952 14/18639 0.0714285714285714 0.682047716627635 0.787611474681232 1 GO:0008195 phosphatidate phosphatase activity 1/1952 14/18639 0.0714285714285714 0.682047716627635 0.787611474681232 1 GO:0008559 ABC-type xenobiotic transporter activity 1/1952 14/18639 0.0714285714285714 0.682047716627635 0.787611474681232 1 GO:0015386 potassium:proton antiporter activity 1/1952 14/18639 0.0714285714285714 0.682047716627635 0.787611474681232 1 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 1/1952 14/18639 0.0714285714285714 0.682047716627635 0.787611474681232 1 GO:0019992 diacylglycerol binding 1/1952 14/18639 0.0714285714285714 0.682047716627635 0.787611474681232 1 GO:0030983 mismatched DNA binding 1/1952 14/18639 0.0714285714285714 0.682047716627635 0.787611474681232 1 GO:0032036 myosin heavy chain binding 1/1952 14/18639 0.0714285714285714 0.682047716627635 0.787611474681232 1 GO:0043176 amine binding 1/1952 14/18639 0.0714285714285714 0.682047716627635 0.787611474681232 1 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/1952 14/18639 0.0714285714285714 0.682047716627635 0.787611474681232 1 GO:0061665 SUMO ligase activity 1/1952 14/18639 0.0714285714285714 0.682047716627635 0.787611474681232 1 GO:0061783 peptidoglycan muralytic activity 1/1952 14/18639 0.0714285714285714 0.682047716627635 0.787611474681232 1 GO:0070742 C2H2 zinc finger domain binding 1/1952 14/18639 0.0714285714285714 0.682047716627635 0.787611474681232 1 GO:0098821 BMP receptor activity 1/1952 14/18639 0.0714285714285714 0.682047716627635 0.787611474681232 1 GO:1901474 azole transmembrane transporter activity 1/1952 14/18639 0.0714285714285714 0.682047716627635 0.787611474681232 1 GO:1990825 sequence-specific mRNA binding 1/1952 14/18639 0.0714285714285714 0.682047716627635 0.787611474681232 1 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 6/1952 73/18639 0.0821917808219178 0.784822030092073 0.789717694952972 1 GO:0000217 DNA secondary structure binding 3/1952 39/18639 0.0769230769230769 0.734512925598991 0.790298487708691 1 GO:0016776 phosphotransferase activity, phosphate group as acceptor 3/1952 39/18639 0.0769230769230769 0.734512925598991 0.790298487708691 1 GO:0035255 ionotropic glutamate receptor binding 2/1952 27/18639 0.0740740740740741 0.707308743169399 0.790451559651269 1 GO:0004867 serine-type endopeptidase inhibitor activity 8/1952 95/18639 0.0842105263157895 0.804098360655738 0.790687398883202 1 GO:0031490 chromatin DNA binding 11/1952 128/18639 0.0859375 0.820588659067623 0.796983363591116 1 GO:0003689 DNA clamp loader activity 14/1952 160/18639 0.0875 0.835508452868852 0.798171074125165 1 GO:0005216 monoatomic ion channel activity 42/1952 448/18639 0.09375 0.895187628073771 0.799751929337688 1 GO:0016407 acetyltransferase activity 8/1952 96/18639 0.0833333333333333 0.795722336065574 0.800156593166622 1 GO:0031491 nucleosome binding 6/1952 74/18639 0.0810810810810811 0.77421632698272 0.800440711551376 1 GO:0019842 vitamin binding 13/1952 150/18639 0.0866666666666667 0.827551229508197 0.802497792112384 1 GO:0022824 transmitter-gated monoatomic ion channel activity 5/1952 63/18639 0.0793650793650794 0.757830796252927 0.802845941078687 1 GO:0022835 transmitter-gated channel activity 5/1952 63/18639 0.0793650793650794 0.757830796252927 0.802845941078687 1 GO:1901682 sulfur compound transmembrane transporter activity 5/1952 63/18639 0.0793650793650794 0.757830796252927 0.802845941078687 1 GO:0004177 aminopeptidase activity 3/1952 40/18639 0.075 0.716150102459016 0.804506148836496 1 GO:0005242 inward rectifier potassium channel activity 2/1952 28/18639 0.0714285714285714 0.682047716627635 0.807141387043029 1 GO:0036408 histone H3K14 acetyltransferase activity 2/1952 28/18639 0.0714285714285714 0.682047716627635 0.807141387043029 1 GO:0046625 sphingolipid binding 2/1952 28/18639 0.0714285714285714 0.682047716627635 0.807141387043029 1 GO:0046875 ephrin receptor binding 2/1952 28/18639 0.0714285714285714 0.682047716627635 0.807141387043029 1 GO:0051119 sugar transmembrane transporter activity 2/1952 28/18639 0.0714285714285714 0.682047716627635 0.807141387043029 1 GO:0051393 alpha-actinin binding 2/1952 28/18639 0.0714285714285714 0.682047716627635 0.807141387043029 1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 7/1952 86/18639 0.0813953488372093 0.777217165459398 0.809425085256041 1 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/1952 15/18639 0.0666666666666667 0.636577868852459 0.809870932475714 1 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/1952 15/18639 0.0666666666666667 0.636577868852459 0.809870932475714 1 GO:0004953 icosanoid receptor activity 1/1952 15/18639 0.0666666666666667 0.636577868852459 0.809870932475714 1 GO:0008242 omega peptidase activity 1/1952 15/18639 0.0666666666666667 0.636577868852459 0.809870932475714 1 GO:0015116 sulfate transmembrane transporter activity 1/1952 15/18639 0.0666666666666667 0.636577868852459 0.809870932475714 1 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/1952 15/18639 0.0666666666666667 0.636577868852459 0.809870932475714 1 GO:0030553 cGMP binding 1/1952 15/18639 0.0666666666666667 0.636577868852459 0.809870932475714 1 GO:0031005 filamin binding 1/1952 15/18639 0.0666666666666667 0.636577868852459 0.809870932475714 1 GO:0033130 acetylcholine receptor binding 1/1952 15/18639 0.0666666666666667 0.636577868852459 0.809870932475714 1 GO:0034483 heparan sulfate sulfotransferase activity 1/1952 15/18639 0.0666666666666667 0.636577868852459 0.809870932475714 1 GO:0045504 dynein heavy chain binding 1/1952 15/18639 0.0666666666666667 0.636577868852459 0.809870932475714 1 GO:0047372 monoacylglycerol lipase activity 1/1952 15/18639 0.0666666666666667 0.636577868852459 0.809870932475714 1 GO:0050700 CARD domain binding 1/1952 15/18639 0.0666666666666667 0.636577868852459 0.809870932475714 1 GO:0051371 muscle alpha-actinin binding 1/1952 15/18639 0.0666666666666667 0.636577868852459 0.809870932475714 1 GO:0061578 K63-linked deubiquitinase activity 1/1952 15/18639 0.0666666666666667 0.636577868852459 0.809870932475714 1 GO:0140161 monocarboxylate:sodium symporter activity 1/1952 15/18639 0.0666666666666667 0.636577868852459 0.809870932475714 1 GO:0016741 transferase activity, transferring one-carbon groups 19/1952 215/18639 0.0883720930232558 0.843835779641632 0.814560366764326 1 GO:0004812 aminoacyl-tRNA ligase activity 3/1952 41/18639 0.0731707317073171 0.698683026789284 0.817894393126821 1 GO:0016875 ligase activity, forming carbon-oxygen bonds 3/1952 41/18639 0.0731707317073171 0.698683026789284 0.817894393126821 1 GO:0017080 sodium channel regulator activity 3/1952 41/18639 0.0731707317073171 0.698683026789284 0.817894393126821 1 GO:0140828 metal cation:monoatomic cation antiporter activity 3/1952 41/18639 0.0731707317073171 0.698683026789284 0.817894393126821 1 GO:0005544 calcium-dependent phospholipid binding 4/1952 53/18639 0.0754716981132075 0.720654191153727 0.819761290067039 1 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 4/1952 53/18639 0.0754716981132075 0.720654191153727 0.819761290067039 1 GO:0005262 calcium channel activity 11/1952 131/18639 0.083969465648855 0.801796552371418 0.820517252218681 1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 2/1952 29/18639 0.0689655172413793 0.658528829847371 0.822635883521367 1 GO:0010484 histone H3 acetyltransferase activity 2/1952 29/18639 0.0689655172413793 0.658528829847371 0.822635883521367 1 GO:0097472 cyclin-dependent protein kinase activity 2/1952 29/18639 0.0689655172413793 0.658528829847371 0.822635883521367 1 GO:0106222 lncRNA binding 2/1952 29/18639 0.0689655172413793 0.658528829847371 0.822635883521367 1 GO:0005261 monoatomic cation channel activity 31/1952 341/18639 0.0909090909090909 0.868060730253353 0.823221383009453 1 GO:0160215 deacylase activity 5/1952 65/18639 0.0769230769230769 0.734512925598991 0.824324516779881 1 GO:0008514 organic anion transmembrane transporter activity 24/1952 269/18639 0.0892193308550186 0.851925772441953 0.824973421790026 1 GO:0004222 metalloendopeptidase activity 9/1952 110/18639 0.0818181818181818 0.781254657228018 0.82645173859861 1 GO:0004197 cysteine-type endopeptidase activity 7/1952 88/18639 0.0795454545454545 0.759553138971684 0.827703002502944 1 GO:0005179 hormone activity 11/1952 132/18639 0.0833333333333333 0.795722336065574 0.827888695838681 1 GO:0003688 DNA replication origin binding 1/1952 16/18639 0.0625 0.59679175204918 0.829798549518638 1 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/1952 16/18639 0.0625 0.59679175204918 0.829798549518638 1 GO:0005149 interleukin-1 receptor binding 1/1952 16/18639 0.0625 0.59679175204918 0.829798549518638 1 GO:0015385 sodium:proton antiporter activity 1/1952 16/18639 0.0625 0.59679175204918 0.829798549518638 1 GO:0015562 efflux transmembrane transporter activity 1/1952 16/18639 0.0625 0.59679175204918 0.829798549518638 1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/1952 16/18639 0.0625 0.59679175204918 0.829798549518638 1 GO:0019841 retinol binding 1/1952 16/18639 0.0625 0.59679175204918 0.829798549518638 1 GO:0022841 potassium ion leak channel activity 1/1952 16/18639 0.0625 0.59679175204918 0.829798549518638 1 GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity 1/1952 16/18639 0.0625 0.59679175204918 0.829798549518638 1 GO:0030275 LRR domain binding 1/1952 16/18639 0.0625 0.59679175204918 0.829798549518638 1 GO:0070411 I-SMAD binding 1/1952 16/18639 0.0625 0.59679175204918 0.829798549518638 1 GO:0004402 histone acetyltransferase activity 3/1952 42/18639 0.0714285714285714 0.682047716627635 0.830494226093109 1 GO:0008307 structural constituent of muscle 3/1952 42/18639 0.0714285714285714 0.682047716627635 0.830494226093109 1 GO:0001965 G-protein alpha-subunit binding 2/1952 30/18639 0.0666666666666667 0.636577868852459 0.837002220798837 1 GO:0016769 transferase activity, transferring nitrogenous groups 2/1952 30/18639 0.0666666666666667 0.636577868852459 0.837002220798837 1 GO:0031624 ubiquitin conjugating enzyme binding 2/1952 30/18639 0.0666666666666667 0.636577868852459 0.837002220798837 1 GO:0043995 histone H4K5 acetyltransferase activity 2/1952 30/18639 0.0666666666666667 0.636577868852459 0.837002220798837 1 GO:0043996 histone H4K8 acetyltransferase activity 2/1952 30/18639 0.0666666666666667 0.636577868852459 0.837002220798837 1 GO:0043997 histone H4K12 acetyltransferase activity 2/1952 30/18639 0.0666666666666667 0.636577868852459 0.837002220798837 1 GO:0048019 receptor antagonist activity 2/1952 30/18639 0.0666666666666667 0.636577868852459 0.837002220798837 1 GO:0016887 ATP hydrolysis activity 38/1952 417/18639 0.0911270983213429 0.870142410661635 0.841025450994469 1 GO:0042054 histone methyltransferase activity 5/1952 67/18639 0.0746268656716418 0.712587166625887 0.843868217458181 1 GO:0005319 lipid transporter activity 15/1952 178/18639 0.0842696629213483 0.804663036470805 0.846480325642851 1 GO:0004550 nucleoside diphosphate kinase activity 1/1952 17/18639 0.0588235294117647 0.561686354869817 0.847638491060796 1 GO:0008484 sulfuric ester hydrolase activity 1/1952 17/18639 0.0588235294117647 0.561686354869817 0.847638491060796 1 GO:0008569 minus-end-directed microtubule motor activity 1/1952 17/18639 0.0588235294117647 0.561686354869817 0.847638491060796 1 GO:0030548 acetylcholine receptor regulator activity 1/1952 17/18639 0.0588235294117647 0.561686354869817 0.847638491060796 1 GO:0046965 nuclear retinoid X receptor binding 1/1952 17/18639 0.0588235294117647 0.561686354869817 0.847638491060796 1 GO:0005452 solute:inorganic anion antiporter activity 2/1952 31/18639 0.0645161290322581 0.616043098889477 0.850306618154142 1 GO:0016411 acylglycerol O-acyltransferase activity 2/1952 31/18639 0.0645161290322581 0.616043098889477 0.850306618154142 1 GO:0016878 acid-thiol ligase activity 2/1952 31/18639 0.0645161290322581 0.616043098889477 0.850306618154142 1 GO:0047499 calcium-independent phospholipase A2 activity 2/1952 31/18639 0.0645161290322581 0.616043098889477 0.850306618154142 1 GO:0070273 phosphatidylinositol-4-phosphate binding 2/1952 31/18639 0.0645161290322581 0.616043098889477 0.850306618154142 1 GO:0030170 pyridoxal phosphate binding 4/1952 56/18639 0.0714285714285714 0.682047716627635 0.851527158487169 1 GO:0005548 phospholipid transporter activity 5/1952 68/18639 0.0735294117647059 0.702107943587271 0.852946774002068 1 GO:0030547 signaling receptor inhibitor activity 3/1952 44/18639 0.0681818181818182 0.651045547690015 0.853456760124556 1 GO:0015085 calcium ion transmembrane transporter activity 12/1952 147/18639 0.0816326530612245 0.779483104717297 0.855319894525784 1 GO:0052689 carboxylic ester hydrolase activity 7/1952 92/18639 0.0760869565217391 0.726529089451176 0.860087790718404 1 GO:0070279 vitamin B6 binding 4/1952 57/18639 0.0701754385964912 0.670081967213115 0.861003914993288 1 GO:0015291 secondary active transmembrane transporter activity 25/1952 287/18639 0.0871080139372822 0.831765508082481 0.861035624308416 1 GO:0008080 N-acetyltransferase activity 5/1952 69/18639 0.072463768115942 0.691932466143977 0.861581448722583 1 GO:0016279 protein-lysine N-methyltransferase activity 5/1952 69/18639 0.072463768115942 0.691932466143977 0.861581448722583 1 GO:0047498 calcium-dependent phospholipase A2 activity 2/1952 32/18639 0.0625 0.59679175204918 0.862613805359439 1 GO:0004706 JUN kinase kinase kinase activity 1/1952 18/18639 0.0555555555555556 0.530481557377049 0.863609367736198 1 GO:0008308 voltage-gated monoatomic anion channel activity 1/1952 18/18639 0.0555555555555556 0.530481557377049 0.863609367736198 1 GO:0031690 adrenergic receptor binding 1/1952 18/18639 0.0555555555555556 0.530481557377049 0.863609367736198 1 GO:0099602 neurotransmitter receptor regulator activity 1/1952 18/18639 0.0555555555555556 0.530481557377049 0.863609367736198 1 GO:1901611 phosphatidylglycerol binding 1/1952 18/18639 0.0555555555555556 0.530481557377049 0.863609367736198 1 GO:1990381 ubiquitin-specific protease binding 1/1952 18/18639 0.0555555555555556 0.530481557377049 0.863609367736198 1 GO:0140303 intramembrane lipid transporter activity 3/1952 45/18639 0.0666666666666667 0.636577868852459 0.863884529019507 1 GO:0061659 ubiquitin-like protein ligase activity 33/1952 372/18639 0.0887096774193548 0.84705926097303 0.866621852318312 1 GO:0099106 ion channel regulator activity 13/1952 160/18639 0.08125 0.775829277663935 0.867319119069734 1 GO:0008028 monocarboxylic acid transmembrane transporter activity 5/1952 70/18639 0.0714285714285714 0.682047716627635 0.869786460655527 1 GO:0016278 lysine N-methyltransferase activity 5/1952 70/18639 0.0714285714285714 0.682047716627635 0.869786460655527 1 GO:0061980 regulatory RNA binding 4/1952 58/18639 0.0689655172413793 0.658528829847371 0.869958491664657 1 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 23/1952 268/18639 0.0858208955223881 0.81947524161977 0.870088168252827 1 GO:0008168 methyltransferase activity 17/1952 204/18639 0.0833333333333333 0.795722336065574 0.870367947151571 1 GO:0019956 chemokine binding 2/1952 33/18639 0.0606060606060606 0.578707153502236 0.873986608437219 1 GO:0140416 transcription regulator inhibitor activity 2/1952 33/18639 0.0606060606060606 0.578707153502236 0.873986608437219 1 GO:0005520 insulin-like growth factor binding 1/1952 19/18639 0.0526315789473684 0.502561475409836 0.87790690890901 1 GO:0008301 DNA binding, bending 1/1952 19/18639 0.0526315789473684 0.502561475409836 0.87790690890901 1 GO:0008574 plus-end-directed microtubule motor activity 1/1952 19/18639 0.0526315789473684 0.502561475409836 0.87790690890901 1 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/1952 19/18639 0.0526315789473684 0.502561475409836 0.87790690890901 1 GO:0016918 retinal binding 1/1952 19/18639 0.0526315789473684 0.502561475409836 0.87790690890901 1 GO:0022840 leak channel activity 1/1952 19/18639 0.0526315789473684 0.502561475409836 0.87790690890901 1 GO:0022842 narrow pore channel activity 1/1952 19/18639 0.0526315789473684 0.502561475409836 0.87790690890901 1 GO:0042800 histone H3K4 methyltransferase activity 1/1952 19/18639 0.0526315789473684 0.502561475409836 0.87790690890901 1 GO:0046527 glucosyltransferase activity 1/1952 19/18639 0.0526315789473684 0.502561475409836 0.87790690890901 1 GO:0097001 ceramide binding 1/1952 19/18639 0.0526315789473684 0.502561475409836 0.87790690890901 1 GO:0099589 serotonin receptor activity 1/1952 19/18639 0.0526315789473684 0.502561475409836 0.87790690890901 1 GO:0008276 protein methyltransferase activity 7/1952 95/18639 0.0736842105263158 0.70358606557377 0.880968498519064 1 GO:0008376 acetylgalactosaminyltransferase activity 2/1952 34/18639 0.0588235294117647 0.561686354869817 0.884485638431065 1 GO:0030332 cyclin binding 2/1952 34/18639 0.0588235294117647 0.561686354869817 0.884485638431065 1 GO:0051427 hormone receptor binding 2/1952 34/18639 0.0588235294117647 0.561686354869817 0.884485638431065 1 GO:0015276 ligand-gated monoatomic ion channel activity 15/1952 186/18639 0.0806451612903226 0.770053873611846 0.887898548607214 1 GO:0004843 cysteine-type deubiquitinase activity 8/1952 108/18639 0.0740740740740741 0.707308743169399 0.889816561908155 1 GO:0001972 retinoic acid binding 1/1952 20/18639 0.05 0.477433401639344 0.890706356482029 1 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/1952 20/18639 0.05 0.477433401639344 0.890706356482029 1 GO:0015464 acetylcholine receptor activity 1/1952 20/18639 0.05 0.477433401639344 0.890706356482029 1 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/1952 20/18639 0.05 0.477433401639344 0.890706356482029 1 GO:0030627 pre-mRNA 5'-splice site binding 1/1952 20/18639 0.05 0.477433401639344 0.890706356482029 1 GO:0008188 neuropeptide receptor activity 3/1952 48/18639 0.0625 0.59679175204918 0.891343565358071 1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 3/1952 48/18639 0.0625 0.59679175204918 0.891343565358071 1 GO:0004623 phospholipase A2 activity 2/1952 35/18639 0.0571428571428571 0.545638173302108 0.89416906617469 1 GO:0005343 organic acid:sodium symporter activity 2/1952 35/18639 0.0571428571428571 0.545638173302108 0.89416906617469 1 GO:0010485 histone H4 acetyltransferase activity 2/1952 35/18639 0.0571428571428571 0.545638173302108 0.89416906617469 1 GO:0034061 DNA polymerase activity 2/1952 35/18639 0.0571428571428571 0.545638173302108 0.89416906617469 1 GO:0022834 ligand-gated channel activity 15/1952 188/18639 0.0797872340425532 0.761861811126613 0.89671300860267 1 GO:0003697 single-stranded DNA binding 9/1952 121/18639 0.0743801652892562 0.710231506570925 0.898031558254865 1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/1952 21/18639 0.0476190476190476 0.454698477751756 0.902164608383156 1 GO:0009975 cyclase activity 1/1952 21/18639 0.0476190476190476 0.454698477751756 0.902164608383156 1 GO:0015125 bile acid transmembrane transporter activity 1/1952 21/18639 0.0476190476190476 0.454698477751756 0.902164608383156 1 GO:0019200 carbohydrate kinase activity 1/1952 21/18639 0.0476190476190476 0.454698477751756 0.902164608383156 1 GO:0061891 calcium ion sensor activity 1/1952 21/18639 0.0476190476190476 0.454698477751756 0.902164608383156 1 GO:0000993 RNA polymerase II complex binding 2/1952 36/18639 0.0555555555555556 0.530481557377049 0.903092468475084 1 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 2/1952 36/18639 0.0555555555555556 0.530481557377049 0.903092468475084 1 GO:0044390 ubiquitin-like protein conjugating enzyme binding 2/1952 36/18639 0.0555555555555556 0.530481557377049 0.903092468475084 1 GO:0008194 UDP-glycosyltransferase activity 11/1952 145/18639 0.0758620689655172 0.724381712832109 0.903885604081377 1 GO:0019003 GDP binding 5/1952 75/18639 0.0666666666666667 0.636577868852459 0.904877778615253 1 GO:0061630 ubiquitin protein ligase activity 30/1952 353/18639 0.084985835694051 0.811501532531463 0.908116833158602 1 GO:0030280 structural constituent of skin epidermis 2/1952 37/18639 0.0540540540540541 0.51614421798848 0.911308733234692 1 GO:0008970 phospholipase A1 activity 1/1952 22/18639 0.0454545454545455 0.434030365126677 0.912422137894171 1 GO:0031683 G-protein beta/gamma-subunit complex binding 1/1952 22/18639 0.0454545454545455 0.434030365126677 0.912422137894171 1 GO:0032931 histone H3K56 acetyltransferase activity 1/1952 22/18639 0.0454545454545455 0.434030365126677 0.912422137894171 1 GO:0043992 histone H3K9 acetyltransferase activity 1/1952 22/18639 0.0454545454545455 0.434030365126677 0.912422137894171 1 GO:0043993 histone H3K18 acetyltransferase activity 1/1952 22/18639 0.0454545454545455 0.434030365126677 0.912422137894171 1 GO:0043994 histone H3K23 acetyltransferase activity 1/1952 22/18639 0.0454545454545455 0.434030365126677 0.912422137894171 1 GO:0043999 histone H2AK5 acetyltransferase activity 1/1952 22/18639 0.0454545454545455 0.434030365126677 0.912422137894171 1 GO:0044012 histone H2AK9 acetyltransferase activity 1/1952 22/18639 0.0454545454545455 0.434030365126677 0.912422137894171 1 GO:0044014 histone H2BK5 acetyltransferase activity 1/1952 22/18639 0.0454545454545455 0.434030365126677 0.912422137894171 1 GO:0044015 histone H2BK12 acetyltransferase activity 1/1952 22/18639 0.0454545454545455 0.434030365126677 0.912422137894171 1 GO:0044016 histone H3K4 acetyltransferase activity 1/1952 22/18639 0.0454545454545455 0.434030365126677 0.912422137894171 1 GO:0044017 histone H3K27 acetyltransferase activity 1/1952 22/18639 0.0454545454545455 0.434030365126677 0.912422137894171 1 GO:0044018 histone H3K36 acetyltransferase activity 1/1952 22/18639 0.0454545454545455 0.434030365126677 0.912422137894171 1 GO:0046972 histone H4K16 acetyltransferase activity 1/1952 22/18639 0.0454545454545455 0.434030365126677 0.912422137894171 1 GO:0140784 metal ion sensor activity 1/1952 22/18639 0.0454545454545455 0.434030365126677 0.912422137894171 1 GO:0140908 histone H3K122 acetyltransferase activity 1/1952 22/18639 0.0454545454545455 0.434030365126677 0.912422137894171 1 GO:0035402 histone H3T11 kinase activity 20/1952 247/18639 0.0809716599190283 0.773171500630517 0.912596138174385 1 GO:0005272 sodium channel activity 3/1952 51/18639 0.0588235294117647 0.561686354869817 0.91372723901262 1 GO:0005501 retinoid binding 2/1952 38/18639 0.0526315789473684 0.502561475409836 0.91886801286524 1 GO:0019840 isoprenoid binding 2/1952 38/18639 0.0526315789473684 0.502561475409836 0.91886801286524 1 GO:0008236 serine-type peptidase activity 15/1952 194/18639 0.077319587628866 0.738299074700017 0.919823016413873 1 GO:0005212 structural constituent of eye lens 1/1952 23/18639 0.0434782608695652 0.415159479686386 0.921604712252584 1 GO:0005283 amino acid:sodium symporter activity 1/1952 23/18639 0.0434782608695652 0.415159479686386 0.921604712252584 1 GO:0016849 phosphorus-oxygen lyase activity 1/1952 23/18639 0.0434782608695652 0.415159479686386 0.921604712252584 1 GO:0044013 histone H2B acetyltransferase activity 1/1952 23/18639 0.0434782608695652 0.415159479686386 0.921604712252584 1 GO:0099186 structural constituent of postsynapse 1/1952 23/18639 0.0434782608695652 0.415159479686386 0.921604712252584 1 GO:0140767 enzyme-substrate adaptor activity 10/1952 139/18639 0.0719424460431655 0.686954534732869 0.926614320961654 1 GO:0016835 carbon-oxygen lyase activity 5/1952 79/18639 0.0632911392405063 0.604346078024486 0.926708042492115 1 GO:0106310 protein serine kinase activity 30/1952 361/18639 0.0831024930747922 0.793518119068162 0.929111117691819 1 GO:0005315 phosphate transmembrane transporter activity 1/1952 24/18639 0.0416666666666667 0.397861168032787 0.929824931509296 1 GO:0043998 histone H2A acetyltransferase activity 1/1952 24/18639 0.0416666666666667 0.397861168032787 0.929824931509296 1 GO:0015144 carbohydrate transmembrane transporter activity 2/1952 40/18639 0.05 0.477433401639344 0.932202536300981 1 GO:0061791 GTPase motor activity 2/1952 40/18639 0.05 0.477433401639344 0.932202536300981 1 GO:1990606 membrane scission GTPase motor activity 2/1952 40/18639 0.05 0.477433401639344 0.932202536300981 1 GO:0017171 serine hydrolase activity 15/1952 198/18639 0.0757575757575758 0.723383941877794 0.93269503836302 1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 19/1952 243/18639 0.0781893004115226 0.746603673345477 0.933518167482864 1 GO:0001216 DNA-binding transcription activator activity 42/1952 491/18639 0.0855397148676171 0.81679034089012 0.934101094326042 1 GO:0015631 tubulin binding 32/1952 385/18639 0.0831168831168831 0.793655524803066 0.934827793698599 1 GO:0003777 microtubule motor activity 4/1952 68/18639 0.0588235294117647 0.561686354869817 0.935264301843282 1 GO:0015101 organic cation transmembrane transporter activity 5/1952 81/18639 0.0617283950617284 0.589423952641166 0.935854376207764 1 GO:0046943 carboxylic acid transmembrane transporter activity 14/1952 188/18639 0.074468085106383 0.711071023718172 0.93661813723273 1 GO:0008374 O-acyltransferase activity 3/1952 55/18639 0.0545454545454545 0.520836438152012 0.937043980356625 1 GO:0008483 transaminase activity 1/1952 25/18639 0.04 0.381946721311475 0.937183606432415 1 GO:0042974 nuclear retinoic acid receptor binding 1/1952 25/18639 0.04 0.381946721311475 0.937183606432415 1 GO:0004676 3-phosphoinositide-dependent protein kinase activity 19/1952 245/18639 0.0775510204081633 0.740508949481432 0.938716462040876 1 GO:0004711 ribosomal protein S6 kinase activity 19/1952 245/18639 0.0775510204081633 0.740508949481432 0.938716462040876 1 GO:0035175 histone H3S10 kinase activity 19/1952 245/18639 0.0775510204081633 0.740508949481432 0.938716462040876 1 GO:0035979 histone H2AXS139 kinase activity 19/1952 245/18639 0.0775510204081633 0.740508949481432 0.938716462040876 1 GO:0044022 histone H3S28 kinase activity 19/1952 245/18639 0.0775510204081633 0.740508949481432 0.938716462040876 1 GO:0044023 histone H4S1 kinase activity 19/1952 245/18639 0.0775510204081633 0.740508949481432 0.938716462040876 1 GO:0044024 histone H2AS1 kinase activity 19/1952 245/18639 0.0775510204081633 0.740508949481432 0.938716462040876 1 GO:0044025 histone H2BS14 kinase activity 19/1952 245/18639 0.0775510204081633 0.740508949481432 0.938716462040876 1 GO:0072354 histone H3T3 kinase activity 19/1952 245/18639 0.0775510204081633 0.740508949481432 0.938716462040876 1 GO:0072371 histone H2AS121 kinase activity 19/1952 245/18639 0.0775510204081633 0.740508949481432 0.938716462040876 1 GO:0072518 Rho-dependent protein serine/threonine kinase activity 19/1952 245/18639 0.0775510204081633 0.740508949481432 0.938716462040876 1 GO:0140823 histone H2BS36 kinase activity 19/1952 245/18639 0.0775510204081633 0.740508949481432 0.938716462040876 1 GO:0140855 histone H3S57 kinase activity 19/1952 245/18639 0.0775510204081633 0.740508949481432 0.938716462040876 1 GO:0140995 histone H2A kinase activity 19/1952 245/18639 0.0775510204081633 0.740508949481432 0.938716462040876 1 GO:0140997 histone H4 kinase activity 19/1952 245/18639 0.0775510204081633 0.740508949481432 0.938716462040876 1 GO:0140998 histone H2B kinase activity 19/1952 245/18639 0.0775510204081633 0.740508949481432 0.938716462040876 1 GO:1990244 histone H2AT120 kinase activity 19/1952 245/18639 0.0775510204081633 0.740508949481432 0.938716462040876 1 GO:0005342 organic acid transmembrane transporter activity 14/1952 189/18639 0.0740740740740741 0.707308743169399 0.939475232844103 1 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 41/1952 484/18639 0.0847107438016529 0.808874771372443 0.940746529083661 1 GO:0004677 DNA-dependent protein kinase activity 19/1952 246/18639 0.0772357723577236 0.7374987504998 0.941183745467001 1 GO:0140857 histone H3T45 kinase activity 19/1952 246/18639 0.0772357723577236 0.7374987504998 0.941183745467001 1 GO:0170055 lipid transmembrane transporter activity 3/1952 56/18639 0.0535714285714286 0.511535787470726 0.941884555179424 1 GO:0035403 histone H3T6 kinase activity 19/1952 247/18639 0.0769230769230769 0.734512925598991 0.943566046074719 1 GO:0005227 calcium-activated cation channel activity 1/1952 26/18639 0.0384615384615385 0.367256462799496 0.943770992284136 1 GO:0008157 protein phosphatase 1 binding 1/1952 26/18639 0.0384615384615385 0.367256462799496 0.943770992284136 1 GO:0051139 metal cation:proton antiporter activity 1/1952 26/18639 0.0384615384615385 0.367256462799496 0.943770992284136 1 GO:0140097 catalytic activity, acting on DNA 27/1952 336/18639 0.0803571428571429 0.767303681206089 0.94524755684042 1 GO:0004679 AMP-activated protein kinase activity 19/1952 248/18639 0.0766129032258065 0.731551179931253 0.945865541338585 1 GO:0008200 ion channel inhibitor activity 2/1952 43/18639 0.0465116279069767 0.444124094548227 0.948374979579892 1 GO:0015293 symporter activity 10/1952 146/18639 0.0684931506849315 0.654018358410061 0.949193713756512 1 GO:0008395 steroid hydroxylase activity 1/1952 27/18639 0.037037037037037 0.353654371584699 0.949667893539246 1 GO:0017116 single-stranded DNA helicase activity 3/1952 58/18639 0.0517241379310345 0.493896622385529 0.950546256755781 1 GO:0016248 channel inhibitor activity 2/1952 44/18639 0.0454545454545455 0.434030365126677 0.95289489479205 1 GO:0043014 alpha-tubulin binding 2/1952 44/18639 0.0454545454545455 0.434030365126677 0.95289489479205 1 GO:0099094 ligand-gated monoatomic cation channel activity 9/1952 136/18639 0.0661764705882353 0.631897149228544 0.954480274408144 1 GO:0015079 potassium ion transmembrane transporter activity 11/1952 160/18639 0.06875 0.656470927254098 0.954639533395813 1 GO:0016866 intramolecular transferase activity 1/1952 28/18639 0.0357142857142857 0.341023858313817 0.954946653039106 1 GO:0019789 SUMO transferase activity 1/1952 28/18639 0.0357142857142857 0.341023858313817 0.954946653039106 1 GO:0050698 proteoglycan sulfotransferase activity 1/1952 28/18639 0.0357142857142857 0.341023858313817 0.954946653039106 1 GO:0051959 dynein light intermediate chain binding 1/1952 28/18639 0.0357142857142857 0.341023858313817 0.954946653039106 1 GO:0003924 GTPase activity 26/1952 331/18639 0.0785498489425982 0.750046431578426 0.956112568802491 1 GO:0141110 transporter inhibitor activity 2/1952 45/18639 0.0444444444444444 0.424385245901639 0.957034911804727 1 GO:0008017 microtubule binding 21/1952 276/18639 0.0760869565217391 0.726529089451176 0.957101920912147 1 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 3/1952 60/18639 0.05 0.477433401639344 0.957990985103603 1 GO:0005416 amino acid:monoatomic cation symporter activity 1/1952 29/18639 0.0344827586206897 0.329264414923686 0.959672037664739 1 GO:0035250 UDP-galactosyltransferase activity 1/1952 29/18639 0.0344827586206897 0.329264414923686 0.959672037664739 1 GO:0008234 cysteine-type peptidase activity 13/1952 187/18639 0.0695187165775401 0.663811146664329 0.961925510651125 1 GO:0015171 amino acid transmembrane transporter activity 6/1952 102/18639 0.0588235294117647 0.561686354869817 0.962922011068847 1 GO:0004252 serine-type endopeptidase activity 12/1952 176/18639 0.0681818181818182 0.651045547690015 0.963485718571984 1 GO:0022839 monoatomic ion-gated channel activity 1/1952 30/18639 0.0333333333333333 0.318288934426229 0.96390203134977 1 GO:0051721 protein phosphatase 2A binding 1/1952 30/18639 0.0333333333333333 0.318288934426229 0.96390203134977 1 GO:0098918 structural constituent of synapse 1/1952 30/18639 0.0333333333333333 0.318288934426229 0.96390203134977 1 GO:0061749 forked DNA-dependent helicase activity 2/1952 47/18639 0.0425531914893617 0.406326299267527 0.964292940224879 1 GO:1990518 single-stranded 3'-5' DNA helicase activity 2/1952 47/18639 0.0425531914893617 0.406326299267527 0.964292940224879 1 GO:0015294 solute:monoatomic cation symporter activity 7/1952 116/18639 0.0603448275862069 0.57621272611645 0.965752736902791 1 GO:0003724 RNA helicase activity 4/1952 77/18639 0.051948051948052 0.496034703001916 0.966864155005608 1 GO:0009378 four-way junction helicase activity 2/1952 48/18639 0.0416666666666667 0.397861168032787 0.96746465217561 1 GO:0036121 double-stranded DNA helicase activity 2/1952 48/18639 0.0416666666666667 0.397861168032787 0.96746465217561 1 GO:0043138 3'-5' DNA helicase activity 2/1952 48/18639 0.0416666666666667 0.397861168032787 0.96746465217561 1 GO:0008378 galactosyltransferase activity 1/1952 32/18639 0.03125 0.29839587602459 0.971078052857265 1 GO:0030515 snoRNA binding 1/1952 32/18639 0.03125 0.29839587602459 0.971078052857265 1 GO:0031369 translation initiation factor binding 1/1952 32/18639 0.03125 0.29839587602459 0.971078052857265 1 GO:0008186 ATP-dependent activity, acting on RNA 4/1952 79/18639 0.0506329113924051 0.483476862419589 0.971576568183526 1 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 12/1952 181/18639 0.0662983425414365 0.633060864052169 0.971984205320776 1 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 7/1952 122/18639 0.0573770491803279 0.547874395323838 0.976759985861636 1 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/1952 34/18639 0.0294117647058824 0.280843177434908 0.976828115709462 1 GO:0004175 endopeptidase activity 31/1952 405/18639 0.0765432098765432 0.730885701275045 0.978469388201835 1 GO:0005246 calcium channel regulator activity 2/1952 53/18639 0.0377358490566038 0.360327095576864 0.979658913769009 1 GO:0005249 voltage-gated potassium channel activity 5/1952 98/18639 0.0510204081632653 0.487176940448311 0.980708527681623 1 GO:0004190 aspartic-type endopeptidase activity 1/1952 36/18639 0.0277777777777778 0.265240778688525 0.981435458389479 1 GO:0070001 aspartic-type peptidase activity 1/1952 37/18639 0.027027027027027 0.25807210899424 0.983383422977112 1 GO:0000146 microfilament motor activity 1/1952 38/18639 0.0263157894736842 0.251280737704918 0.985127082709866 1 GO:0042162 telomeric DNA binding 1/1952 38/18639 0.0263157894736842 0.251280737704918 0.985127082709866 1 GO:0003678 DNA helicase activity 3/1952 74/18639 0.0405405405405405 0.38710816349136 0.987145735090356 1 GO:0017022 myosin binding 3/1952 76/18639 0.0394736842105263 0.376921106557377 0.989202376338436 1 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/1952 41/18639 0.024390243902439 0.232894342263095 0.989335425525055 1 GO:0035198 miRNA binding 1/1952 42/18639 0.0238095238095238 0.227349238875878 0.990454752838481 1 GO:0022832 voltage-gated channel activity 10/1952 175/18639 0.0571428571428571 0.545638173302108 0.990642866961147 1 GO:0015179 L-amino acid transmembrane transporter activity 2/1952 62/18639 0.032258064516129 0.308021549444738 0.991408419643506 1 GO:0005245 voltage-gated calcium channel activity 1/1952 43/18639 0.0232558139534884 0.222062047274114 0.991456652201781 1 GO:0015081 sodium ion transmembrane transporter activity 9/1952 164/18639 0.0548780487804878 0.524012270091963 0.991768179070023 1 GO:0005267 potassium channel activity 6/1952 124/18639 0.0483870967741935 0.462032324167107 0.992096856171698 1 GO:0042605 peptide antigen binding 1/1952 45/18639 0.0222222222222222 0.21219262295082 0.993156131018119 1 GO:0004386 helicase activity 8/1952 155/18639 0.0516129032258065 0.492834479111581 0.99383671405862 1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/1952 46/18639 0.0217391304347826 0.207579739843193 0.993874601075805 1 GO:0005244 voltage-gated monoatomic ion channel activity 9/1952 173/18639 0.0520231213872832 0.496751516156543 0.995466224119574 1 GO:0016597 amino acid binding 1/1952 51/18639 0.0196078431372549 0.187228784956606 0.996482316750652 1 GO:0022836 gated channel activity 20/1952 318/18639 0.0628930817610063 0.600545159294773 0.996661538735748 1 GO:0004497 monooxygenase activity 4/1952 106/18639 0.0377358490566038 0.360327095576864 0.996843376641488 1 GO:0003774 cytoskeletal motor activity 7/1952 153/18639 0.0457516339869281 0.436867164898746 0.997365071488837 1 GO:0003730 mRNA 3'-UTR binding 15/1952 262/18639 0.0572519083969466 0.546679467525967 0.99767350378629 1 GO:0019001 guanyl nucleotide binding 26/1952 400/18639 0.065 0.620663422131148 0.997937887775196 1 GO:0032561 guanyl ribonucleotide binding 26/1952 400/18639 0.065 0.620663422131148 0.997937887775196 1 GO:0022843 voltage-gated monoatomic cation channel activity 6/1952 143/18639 0.041958041958042 0.400643413963086 0.998139076837466 1 GO:0005525 GTP binding 24/1952 378/18639 0.0634920634920635 0.606264637002342 0.998151859878641 1 GO:0046873 metal ion transmembrane transporter activity 30/1952 450/18639 0.0666666666666667 0.636577868852459 0.99815585326303 1 GO:0015370 solute:sodium symporter activity 2/1952 79/18639 0.0253164556962025 0.241738431209795 0.998384667541166 1 GO:0005549 odorant binding 1/1952 111/18639 0.00900900900900901 0.0860240363314134 0.999995529375208 1 GO:0003823 antigen binding 3/1952 174/18639 0.0172413793103448 0.164632207461843 0.999999079579011 1 GO:0045182 translation regulator activity 7/1952 356/18639 0.0196629213483146 0.187754708509854 0.999999999952048 1 GO:0030371 translation repressor activity 4/1952 329/18639 0.0121580547112462 0.116093228362151 0.999999999998805 1 GO:0004984 olfactory receptor activity 1/1952 419/18639 0.00238663484486874 0.0227891838491334 1 1