ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	133/3469	175/18639	0.76	4.08349380224849	1.27200447827074e-61	1.70575800536106e-58
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	58/3469	68/18639	0.852941176470588	4.58286843131603	1.19413936264453e-32	8.00670442653157e-30
GO:0009055	electron transfer activity	78/3469	116/18639	0.672413793103448	3.61289152195306	1.61631496162244e-30	7.22492787845229e-28
GO:0022853	active monoatomic ion transmembrane transporter activity	72/3469	118/18639	0.610169491525424	3.27845175916471	2.13033624623062e-24	7.14195226548817e-22
GO:0015078	proton transmembrane transporter activity	95/3469	185/18639	0.513513513513513	2.75911743395168	6.75316030859239e-24	1.81119759476448e-21
GO:0008137	NADH dehydrogenase (ubiquinone) activity	36/3469	41/18639	0.878048780487805	4.71777204367604	1.23810669389963e-21	2.76716846086568e-19
GO:0003954	NADH dehydrogenase activity	37/3469	44/18639	0.840909090909091	4.51821981708116	7.86035174412676e-21	1.50581881269628e-18
GO:0015399	primary active transmembrane transporter activity	80/3469	166/18639	0.481927710843373	2.58940634257989	3.46926271669091e-18	5.81535162885313e-16
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	40/3469	58/18639	0.689655172413793	3.7055297661057	6.54297088695968e-17	9.74902662156993e-15
GO:0019843	rRNA binding	40/3469	65/18639	0.615384615384615	3.30647271437124	2.37202273894602e-14	3.18088249292662e-12
GO:0016651	oxidoreductase activity, acting on NAD(P)H	47/3469	88/18639	0.534090909090909	2.86968015409209	2.32315651007447e-13	2.83213898182715e-11
GO:0004129	cytochrome-c oxidase activity	14/3469	15/18639	0.933333333333333	5.01481695012972	7.26410730272015e-10	8.11763991078977e-08
GO:0016675	oxidoreductase activity, acting on a heme group of donors	14/3469	16/18639	0.875	4.70139089074661	4.80603098113495e-09	4.79028990150197e-07
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	15/3469	18/18639	0.833333333333333	4.47751513404439	5.00104836845844e-09	4.79028990150197e-07
GO:0055105	ubiquitin-protein transferase inhibitor activity	12/3469	15/18639	0.8	4.29841452868262	4.40704990816207e-07	3.93990261789689e-05
GO:0043021	ribonucleoprotein complex binding	59/3469	177/18639	0.333333333333333	1.79100605361776	1.97478385790176e-06	0.000165511572090391
GO:0015252	proton channel activity	16/3469	27/18639	0.592592592592593	3.18401076198712	3.21364481400329e-06	0.000253499864445789
GO:0032977	membrane insertase activity	12/3469	17/18639	0.705882352941177	3.79271870177878	4.12319452421701e-06	0.000307177992054167
GO:0031625	ubiquitin protein ligase binding	88/3469	302/18639	0.291390728476821	1.56564767601022	5.02256002439513e-06	0.00035448699961652
GO:0016504	peptidase activator activity	25/3469	57/18639	0.43859649122807	2.35658691265494	1.00803374310182e-05	0.000647503375696735
GO:1990948	ubiquitin ligase inhibitor activity	9/3469	11/18639	0.818181818181818	4.39610576797086	1.01398738923426e-05	0.000647503375696735
GO:0030695	GTPase regulator activity	129/3469	489/18639	0.263803680981595	1.41742196881405	1.14974952125987e-05	0.000700824594549765
GO:0060589	nucleoside-triphosphatase regulator activity	129/3469	490/18639	0.263265306122449	1.41452927091851	1.27901705654632e-05	0.000722349435064332
GO:0003743	translation initiation factor activity	23/3469	51/18639	0.450980392156863	2.42312583724755	1.29437569332177e-05	0.000722349435064332
GO:0044389	ubiquitin-like protein ligase binding	91/3469	322/18639	0.282608695652174	1.51846165415419	1.34666188490741e-05	0.000722349435064332
GO:0061133	endopeptidase activator activity	13/3469	22/18639	0.590909090909091	3.17496527686784	2.8861985850518e-05	0.00148861242405941
GO:0051537	2 iron, 2 sulfur cluster binding	15/3469	28/18639	0.535714285714286	2.8784025861714	3.44380509140399e-05	0.00171042319539731
GO:0022804	active transmembrane transporter activity	119/3469	457/18639	0.260393873085339	1.39910100906245	4.59197035759325e-05	0.00213188444862779
GO:0008135	translation factor activity, RNA binding	31/3469	83/18639	0.373493975903614	2.00678991549941	4.61033922522043e-05	0.00213188444862779
GO:0051536	iron-sulfur cluster binding	29/3469	76/18639	0.381578947368421	2.0502306140098	5.08077000885647e-05	0.00227110419395884
GO:0031386	protein tag activity	10/3469	15/18639	0.666666666666667	3.58201210723551	5.89936464718055e-05	0.00244491315179634
GO:0141047	molecular tag activity	10/3469	15/18639	0.666666666666667	3.58201210723551	5.89936464718055e-05	0.00244491315179634
GO:0180051	translation factor activity	31/3469	84/18639	0.369047619047619	1.98289955936252	6.01656480307824e-05	0.00244491315179634
GO:0051540	metal cluster binding	29/3469	77/18639	0.376623376623377	2.02360424239928	6.71398278858736e-05	0.00264807379985166
GO:0070990	snRNP binding	8/3469	11/18639	0.727272727272727	3.90764957152965	0.00013752371151602	0.00526912277551378
GO:0019205	nucleobase-containing compound kinase activity	19/3469	44/18639	0.431818181818182	2.32016693309573	0.000148275484462343	0.00552326179622229
GO:0016530	metallochaperone activity	9/3469	14/18639	0.642857142857143	3.45408310340567	0.000214012380518653	0.00758148764274581
GO:0019207	kinase regulator activity	78/3469	287/18639	0.271777003484321	1.46026277542354	0.000214837084581909	0.00758148764274581
GO:0016776	phosphotransferase activity, phosphate group as acceptor	17/3469	39/18639	0.435897435897436	2.3420848393463	0.000285965122511601	0.00983280075097583
GO:0055106	ubiquitin-protein transferase regulator activity	16/3469	36/18639	0.444444444444444	2.38800807149034	0.000328106274716263	0.0109997628598627
GO:0033218	amide binding	68/3469	247/18639	0.275303643724696	1.47921147748187	0.000355865802470989	0.011639415636917
GO:0043022	ribosome binding	36/3469	112/18639	0.321428571428571	1.72704155170284	0.00040812136661027	0.0130307322053422
GO:0072542	protein phosphatase activator activity	11/3469	21/18639	0.523809523809524	2.81443808425648	0.000507344342560362	0.0158220642644987
GO:0140297	DNA-binding transcription factor binding	120/3469	488/18639	0.245901639344262	1.32123397398031	0.000529946608413689	0.0161513273155172
GO:0047429	nucleoside triphosphate diphosphatase activity	7/3469	10/18639	0.7	3.76111271259729	0.000543391190164895	0.0161930574669139
GO:0001540	amyloid-beta binding	28/3469	83/18639	0.337349397590361	1.81258443980592	0.000736294091237161	0.021407339689023
GO:0035325	Toll-like receptor binding	8/3469	13/18639	0.615384615384615	3.30647271437124	0.000750294530487755	0.021407339689023
GO:0004860	protein kinase inhibitor activity	28/3469	84/18639	0.333333333333333	1.79100605361776	0.000911046494689981	0.0254523614454013
GO:0051082	unfolded protein binding	37/3469	121/18639	0.305785123966942	1.64298902439315	0.000985520440702293	0.0269710798159546
GO:0051287	NAD binding	20/3469	54/18639	0.37037037037037	1.99000672624195	0.0011113478394169	0.0295665384974333
GO:0005085	guanyl-nucleotide exchange factor activity	62/3469	230/18639	0.269565217391304	1.44837880857784	0.00112445448424243	0.0295665384974333
GO:0005096	GTPase activator activity	71/3469	271/18639	0.261992619926199	1.407691104873	0.00120464715350912	0.0310659967856871
GO:0050786	RAGE receptor binding	7/3469	11/18639	0.636363636363636	3.41919337508845	0.00125365927780043	0.0314891516207922
GO:0016829	lyase activity	55/3469	200/18639	0.275	1.47757999423465	0.00126801952835405	0.0314891516207922
GO:0005178	integrin binding	46/3469	161/18639	0.285714285714286	1.53514804595808	0.00130947384427996	0.0319273531850804
GO:0019210	kinase inhibitor activity	29/3469	90/18639	0.322222222222222	1.7313058518305	0.00136407453152871	0.0326647133353571
GO:0019838	growth factor binding	40/3469	136/18639	0.294117647058824	1.58029945907449	0.00144723338600866	0.0339822971261404
GO:0019887	protein kinase regulator activity	67/3469	255/18639	0.262745098039216	1.41173418343988	0.00150221330729892	0.0339822971261404
GO:0004550	nucleoside diphosphate kinase activity	9/3469	17/18639	0.529411764705882	2.84453902633408	0.00151290001848999	0.0339822971261404
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	21/3469	59/18639	0.355932203389831	1.91243019284608	0.00152046072152754	0.0339822971261404
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	23/3469	67/18639	0.343283582089552	1.84446892088993	0.00162373826336357	0.0356956231339433
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	87/3469	349/18639	0.249283667621777	1.33940567333592	0.0018910051649299	0.0409006117124353
GO:0004857	enzyme inhibitor activity	101/3469	416/18639	0.242788461538462	1.30450681309178	0.00215154742655764	0.0457972237938698
GO:0004601	peroxidase activity	20/3469	57/18639	0.350877192982456	1.88526953012396	0.00237124389405335	0.0492911901888688
GO:0016859	cis-trans isomerase activity	16/3469	42/18639	0.380952380952381	2.04686406127744	0.00242596461779667	0.0492911901888688
GO:0048487	beta-tubulin binding	16/3469	42/18639	0.380952380952381	2.04686406127744	0.00242596461779667	0.0492911901888688
GO:0038024	cargo receptor activity	22/3469	65/18639	0.338461538461538	1.81855999290418	0.00248798660932794	0.0497968663150563
GO:0004725	protein tyrosine phosphatase activity	30/3469	98/18639	0.306122448979592	1.64480147781223	0.00277596786278451	0.0547437191763827
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	19/3469	54/18639	0.351851851851852	1.89050638992986	0.00290785341077557	0.0564023946216994
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	15/3469	39/18639	0.384615384615385	2.06654544648203	0.00294419658726246	0.0564023946216994
GO:0019211	phosphatase activator activity	11/3469	25/18639	0.44	2.36412799077544	0.00308672321713175	0.0582999413263899
GO:0030515	snoRNA binding	13/3469	32/18639	0.40625	2.18278862784664	0.00314687433682709	0.0586105345234045
GO:0140517	protein-RNA adaptor activity	10/3469	22/18639	0.454545454545455	2.44228098220603	0.00355551874345101	0.0653143922598329
GO:0005507	copper ion binding	21/3469	63/18639	0.333333333333333	1.79100605361776	0.00379180525249929	0.0687136600486696
GO:0031720	haptoglobin binding	6/3469	10/18639	0.6	3.22381089651196	0.00436423560384157	0.0759653471452593
GO:0033204	ribonuclease P RNA binding	6/3469	10/18639	0.6	3.22381089651196	0.00436423560384157	0.0759653471452593
GO:0038187	pattern recognition receptor activity	17/3469	48/18639	0.354166666666667	1.90294393196887	0.00438176880066211	0.0759653471452593
GO:0048306	calcium-dependent protein binding	25/3469	80/18639	0.3125	1.67906817526665	0.0044510927566685	0.0759653471452593
GO:0004721	phosphoprotein phosphatase activity	47/3469	175/18639	0.268571428571429	1.44303916320059	0.00449253469450472	0.0759653471452593
GO:0031072	heat shock protein binding	37/3469	131/18639	0.282442748091603	1.51757001489749	0.00453186261865827	0.0759653471452593
GO:0035673	oligopeptide transmembrane transporter activity	7/3469	13/18639	0.538461538461538	2.89316362507484	0.004597316030709	0.076111120952849
GO:0016853	isomerase activity	48/3469	180/18639	0.266666666666667	1.43280484289421	0.00477638594580091	0.0781113847965734
GO:0002020	protease binding	38/3469	136/18639	0.279411764705882	1.50128448612077	0.00494286399155102	0.0793889792981976
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	27/3469	89/18639	0.303370786516854	1.6300167454274	0.00503211278176495	0.0793889792981976
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	27/3469	89/18639	0.303370786516854	1.6300167454274	0.00503211278176495	0.0793889792981976
GO:0016860	intramolecular oxidoreductase activity	18/3469	53/18639	0.339622641509434	1.82479862066715	0.00568006181321267	0.0885693359478859
GO:0140793	histone H2AXY142 phosphatase activity	27/3469	90/18639	0.3	1.61190544825598	0.00593958689846578	0.0915515635729035
GO:0016505	peptidase activator activity involved in apoptotic process	9/3469	20/18639	0.45	2.41785817238397	0.00611205149226293	0.092495569808835
GO:0016209	antioxidant activity	26/3469	86/18639	0.302325581395349	1.62440083932773	0.00613878129230896	0.092495569808835
GO:0005044	scavenger receptor activity	11/3469	27/18639	0.407407407407407	2.18900739886615	0.00627951659117438	0.0925366126237895
GO:0023026	MHC class II protein complex binding	11/3469	27/18639	0.407407407407407	2.18900739886615	0.00627951659117438	0.0925366126237895
GO:0042625	ATPase-coupled ion transmembrane transporter activity	10/3469	24/18639	0.416666666666667	2.2387575670222	0.00752427219010155	0.107340946882193
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	10/3469	24/18639	0.416666666666667	2.2387575670222	0.00752427219010155	0.107340946882193
GO:0046961	proton-transporting ATPase activity, rotational mechanism	10/3469	24/18639	0.416666666666667	2.2387575670222	0.00752427219010155	0.107340946882193
GO:0005344	oxygen carrier activity	7/3469	14/18639	0.5	2.68650908042664	0.00772929466430478	0.109105096261397
GO:0019864	IgG binding	6/3469	11/18639	0.545454545454545	2.93073717864724	0.00809692719509095	0.112727708504275
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	14/3469	39/18639	0.358974358974359	1.92877575004989	0.00815405497756499	0.112727708504275
GO:0044325	transmembrane transporter binding	37/3469	136/18639	0.272058823529412	1.4617769996439	0.0086912984954256	0.117727588710765
GO:0140789	histone phosphatase activity	37/3469	136/18639	0.272058823529412	1.4617769996439	0.0086912984954256	0.117727588710765
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	35/3469	128/18639	0.2734375	1.46918465335832	0.0096730584308225	0.12971571355733
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	13/3469	36/18639	0.361111111111111	1.9402565580859	0.0100484741849811	0.130825280408346
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	13/3469	36/18639	0.361111111111111	1.9402565580859	0.0100484741849811	0.130825280408346
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	13/3469	36/18639	0.361111111111111	1.9402565580859	0.0100484741849811	0.130825280408346
GO:0015036	disulfide oxidoreductase activity	14/3469	40/18639	0.35	1.88055635629865	0.0104382697718079	0.132099484874103
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	14/3469	40/18639	0.35	1.88055635629865	0.0104382697718079	0.132099484874103
GO:0004706	JUN kinase kinase kinase activity	8/3469	18/18639	0.444444444444444	2.38800807149034	0.0105403764962931	0.132099484874103
GO:0070064	proline-rich region binding	8/3469	18/18639	0.444444444444444	2.38800807149034	0.0105403764962931	0.132099484874103
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	7/3469	15/18639	0.466666666666667	2.50740847506486	0.0121914603575731	0.149988516876197
GO:0050700	CARD domain binding	7/3469	15/18639	0.466666666666667	2.50740847506486	0.0121914603575731	0.149988516876197
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	19/3469	61/18639	0.311475409836066	1.6735630337084	0.0126441061208334	0.153160490780699
GO:0008093	cytoskeletal anchor activity	9/3469	22/18639	0.409090909090909	2.19805288398543	0.0126907023482362	0.153160490780699
GO:0019208	phosphatase regulator activity	32/3469	117/18639	0.273504273504274	1.46954342860944	0.0128871675562355	0.153160490780699
GO:0023023	MHC protein complex binding	13/3469	37/18639	0.351351351351351	1.88781719165115	0.0129061412812968	0.153160490780699
GO:0140296	general transcription initiation factor binding	17/3469	53/18639	0.320754716981132	1.72342091951897	0.0131430202963668	0.154603422959893
GO:0004300	enoyl-CoA hydratase activity	6/3469	12/18639	0.5	2.68650908042664	0.0136680114749766	0.156656439213194
GO:0004526	ribonuclease P activity	6/3469	12/18639	0.5	2.68650908042664	0.0136680114749766	0.156656439213194
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	6/3469	12/18639	0.5	2.68650908042664	0.0136680114749766	0.156656439213194
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	33/3469	122/18639	0.270491803278689	1.45335737137834	0.0138204756121347	0.157061506744683
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	10/3469	26/18639	0.384615384615385	2.06654544648203	0.0142461055602792	0.160538046691886
GO:1901681	sulfur compound binding	66/3469	275/18639	0.24	1.28952435860479	0.0146408797837974	0.163025547635546
GO:0019001	guanyl nucleotide binding	92/3469	400/18639	0.23	1.23579417699625	0.0150267488342232	0.163025547635546
GO:0032561	guanyl ribonucleotide binding	92/3469	400/18639	0.23	1.23579417699625	0.0150267488342232	0.163025547635546
GO:0005201	extracellular matrix structural constituent	43/3469	168/18639	0.255952380952381	1.37523679117078	0.0150927985696802	0.163025547635546
GO:0008301	DNA binding, bending	8/3469	19/18639	0.421052631578947	2.26232343614875	0.0152839299915242	0.163025547635546
GO:0050145	nucleoside monophosphate kinase activity	8/3469	19/18639	0.421052631578947	2.26232343614875	0.0152839299915242	0.163025547635546
GO:0046332	SMAD binding	23/3469	79/18639	0.291139240506329	1.56429642657753	0.0153178366905882	0.163025547635546
GO:0015035	protein-disulfide reductase activity	12/3469	34/18639	0.352941176470588	1.89635935088939	0.0159832177075821	0.168767676739115
GO:0004197	cysteine-type endopeptidase activity	25/3469	88/18639	0.284090909090909	1.52642561387877	0.0161866170693332	0.169580105390436
GO:0016922	nuclear receptor binding	36/3469	137/18639	0.262773722627737	1.41188798387385	0.0165474849702186	0.1720168786439
GO:0042578	phosphoric ester hydrolase activity	84/3469	363/18639	0.231404958677686	1.24334304548671	0.0167680385752957	0.172968767149781
GO:0005525	GTP binding	87/3469	378/18639	0.23015873015873	1.23664703702178	0.0173265962603656	0.177366149504964
GO:0140102	catalytic activity, acting on a rRNA	9/3469	23/18639	0.391304347826087	2.10248536729041	0.0174718846818926	0.1774984648365
GO:0051087	protein-folding chaperone binding	35/3469	134/18639	0.261194029850746	1.40340026589451	0.019601258260108	0.197633739299285
GO:0032934	sterol binding	20/3469	68/18639	0.294117647058824	1.58029945907449	0.0203641914116455	0.203793885694154
GO:0016004	phospholipase activator activity	8/3469	20/18639	0.4	2.14920726434131	0.0213985156576984	0.207972452001769
GO:0043024	ribosomal small subunit binding	8/3469	20/18639	0.4	2.14920726434131	0.0213985156576984	0.207972452001769
GO:0005035	death receptor activity	6/3469	13/18639	0.461538461538462	2.47985453577843	0.0214428932843489	0.207972452001769
GO:0070700	BMP receptor binding	6/3469	13/18639	0.461538461538462	2.47985453577843	0.0214428932843489	0.207972452001769
GO:0019955	cytokine binding	37/3469	144/18639	0.256944444444444	1.38056716633035	0.0215571743685652	0.207972452001769
GO:0043539	protein serine/threonine kinase activator activity	21/3469	73/18639	0.287671232876712	1.54566275860163	0.0227092286020651	0.217518045918494
GO:0045296	cadherin binding	77/3469	334/18639	0.230538922155689	1.23868981552605	0.023075053308123	0.217518045918494
GO:0048027	mRNA 5'-UTR binding	9/3469	24/18639	0.375	2.01488181031998	0.0234404521769673	0.217518045918494
GO:0060229	lipase activator activity	9/3469	24/18639	0.375	2.01488181031998	0.0234404521769673	0.217518045918494
GO:0005080	protein kinase C binding	16/3469	52/18639	0.307692307692308	1.65323635718562	0.0236346083200645	0.217518045918494
GO:0001094	TFIID-class transcription factor complex binding	5/3469	10/18639	0.5	2.68650908042664	0.0244382285753729	0.217518045918494
GO:0005031	tumor necrosis factor receptor activity	5/3469	10/18639	0.5	2.68650908042664	0.0244382285753729	0.217518045918494
GO:0005528	FK506 binding	5/3469	10/18639	0.5	2.68650908042664	0.0244382285753729	0.217518045918494
GO:0043422	protein kinase B binding	5/3469	10/18639	0.5	2.68650908042664	0.0244382285753729	0.217518045918494
GO:0070513	death domain binding	5/3469	10/18639	0.5	2.68650908042664	0.0244382285753729	0.217518045918494
GO:0097177	mitochondrial ribosome binding	5/3469	10/18639	0.5	2.68650908042664	0.0244382285753729	0.217518045918494
GO:0046625	sphingolipid binding	10/3469	28/18639	0.357142857142857	1.9189350574476	0.0246552893211119	0.217518045918494
GO:0046875	ephrin receptor binding	10/3469	28/18639	0.357142857142857	1.9189350574476	0.0246552893211119	0.217518045918494
GO:0120015	sterol transfer activity	11/3469	32/18639	0.34375	1.84697499279331	0.0252627073355863	0.217661025338976
GO:0016791	phosphatase activity	64/3469	273/18639	0.234432234432234	1.25960865309381	0.0257896460516603	0.217661025338976
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	34/3469	132/18639	0.257575757575758	1.38395922325009	0.0258117377701266	0.217661025338976
GO:0004549	tRNA-specific ribonuclease activity	7/3469	17/18639	0.411764705882353	2.21241924270429	0.0261323080384602	0.217661025338976
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	7/3469	17/18639	0.411764705882353	2.21241924270429	0.0261323080384602	0.217661025338976
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	7/3469	17/18639	0.411764705882353	2.21241924270429	0.0261323080384602	0.217661025338976
GO:0015278	intracellularly gated calcium channel activity	7/3469	17/18639	0.411764705882353	2.21241924270429	0.0261323080384602	0.217661025338976
GO:0019198	transmembrane receptor protein phosphatase activity	7/3469	17/18639	0.411764705882353	2.21241924270429	0.0261323080384602	0.217661025338976
GO:0070403	NAD+ binding	7/3469	17/18639	0.411764705882353	2.21241924270429	0.0261323080384602	0.217661025338976
GO:0061134	peptidase regulator activity	54/3469	226/18639	0.238938053097345	1.28381849861096	0.0272456341338677	0.225533304774794
GO:0043178	alcohol binding	25/3469	92/18639	0.271739130434783	1.46005928284056	0.0277446376701628	0.228254963899929
GO:0051539	4 iron, 4 sulfur cluster binding	14/3469	45/18639	0.311111111111111	1.67160565004324	0.0300982249653869	0.246108046820633
GO:0044183	protein folding chaperone	21/3469	75/18639	0.28	1.50444508503892	0.0303157862240639	0.246384662584665
GO:0004709	MAP kinase kinase kinase activity	9/3469	25/18639	0.36	1.93428653790718	0.0307292225547155	0.246753817041159
GO:0017025	TBP-class protein binding	9/3469	25/18639	0.36	1.93428653790718	0.0307292225547155	0.246753817041159
GO:0140416	transcription regulator inhibitor activity	11/3469	33/18639	0.333333333333333	1.79100605361776	0.0316959059352824	0.250278657096595
GO:0019763	immunoglobulin receptor activity	6/3469	14/18639	0.428571428571429	2.30272206893712	0.031728092249382	0.250278657096595
GO:0034236	protein kinase A catalytic subunit binding	6/3469	14/18639	0.428571428571429	2.30272206893712	0.031728092249382	0.250278657096595
GO:0019209	kinase activator activity	37/3469	148/18639	0.25	1.34325454021332	0.0321185827559322	0.251877306875468
GO:0051020	GTPase binding	72/3469	315/18639	0.228571428571429	1.22811843676646	0.0324261705197131	0.252811015505437
GO:0015485	cholesterol binding	16/3469	54/18639	0.296296296296296	1.59200538099356	0.0333236892573459	0.255354670252005
GO:0017069	snRNA binding	16/3469	54/18639	0.296296296296296	1.59200538099356	0.0333236892573459	0.255354670252005
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	16/3469	54/18639	0.296296296296296	1.59200538099356	0.0333236892573459	0.255354670252005
GO:0003697	single-stranded DNA binding	31/3469	121/18639	0.256198347107438	1.37655837178885	0.0344191231107114	0.262250250519681
GO:0032813	tumor necrosis factor receptor superfamily binding	15/3469	50/18639	0.3	1.61190544825598	0.034730959161546	0.263131165173069
GO:0004722	protein serine/threonine phosphatase activity	27/3469	103/18639	0.262135922330097	1.40846107129163	0.0353443972706498	0.264390218878534
GO:0003746	translation elongation factor activity	7/3469	18/18639	0.388888888888889	2.08950706255405	0.0360544462925666	0.264390218878534
GO:0030228	lipoprotein particle receptor activity	7/3469	18/18639	0.388888888888889	2.08950706255405	0.0360544462925666	0.264390218878534
GO:0032393	MHC class I receptor activity	7/3469	18/18639	0.388888888888889	2.08950706255405	0.0360544462925666	0.264390218878534
GO:1990381	ubiquitin-specific protease binding	7/3469	18/18639	0.388888888888889	2.08950706255405	0.0360544462925666	0.264390218878534
GO:0030291	protein serine/threonine kinase inhibitor activity	14/3469	46/18639	0.304347826086957	1.63526639678143	0.0360800969834241	0.264390218878534
GO:0140104	molecular carrier activity	58/3469	249/18639	0.232931726907631	1.25154639891361	0.0363715264563512	0.265077266184603
GO:0042056	chemoattractant activity	13/3469	42/18639	0.30952380952381	1.66307704978792	0.0373245200809107	0.269667870585562
GO:0019206	nucleoside kinase activity	5/3469	11/18639	0.454545454545455	2.44228098220603	0.0380559797256079	0.269667870585562
GO:0042608	T cell receptor binding	5/3469	11/18639	0.454545454545455	2.44228098220603	0.0380559797256079	0.269667870585562
GO:0048407	platelet-derived growth factor binding	5/3469	11/18639	0.454545454545455	2.44228098220603	0.0380559797256079	0.269667870585562
GO:0140537	transcription regulator activator activity	5/3469	11/18639	0.454545454545455	2.44228098220603	0.0380559797256079	0.269667870585562
GO:0008649	rRNA methyltransferase activity	8/3469	22/18639	0.363636363636364	1.95382478576483	0.0384090703071158	0.269667870585562
GO:0033691	sialic acid binding	8/3469	22/18639	0.363636363636364	1.95382478576483	0.0384090703071158	0.269667870585562
GO:0004112	cyclic-nucleotide phosphodiesterase activity	9/3469	26/18639	0.346153846153846	1.85989090183382	0.0394555786105936	0.275572556858364
GO:0008200	ion channel inhibitor activity	13/3469	43/18639	0.302325581395349	1.62440083932773	0.0446789708405905	0.306189390906625
GO:0005041	low-density lipoprotein particle receptor activity	6/3469	15/18639	0.4	2.14920726434131	0.044752513510588	0.306189390906625
GO:0016846	carbon-sulfur lyase activity	6/3469	15/18639	0.4	2.14920726434131	0.044752513510588	0.306189390906625
GO:0050780	dopamine receptor binding	6/3469	15/18639	0.4	2.14920726434131	0.044752513510588	0.306189390906625
GO:0019212	phosphatase inhibitor activity	16/3469	56/18639	0.285714285714286	1.53514804595808	0.0456346207932157	0.310639728343666
GO:0003684	damaged DNA binding	20/3469	74/18639	0.27027027027027	1.45216707050088	0.0478972129297693	0.324394760297074
GO:0008171	O-methyltransferase activity	8/3469	23/18639	0.347826086956522	1.86887588203592	0.0495755693072348	0.333353830915254
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	9/3469	27/18639	0.333333333333333	1.79100605361776	0.0497172007330729	0.333353830915254
GO:0016248	channel inhibitor activity	13/3469	44/18639	0.295454545454545	1.58748263843392	0.0529844242047665	0.352574684363415
GO:0019888	protein phosphatase regulator activity	27/3469	107/18639	0.252336448598131	1.35580832096297	0.0543424831142975	0.352574684363415
GO:0005095	GTPase inhibitor activity	5/3469	12/18639	0.416666666666667	2.2387575670222	0.0554759570474874	0.352574684363415
GO:0005527	macrolide binding	5/3469	12/18639	0.416666666666667	2.2387575670222	0.0554759570474874	0.352574684363415
GO:0016208	AMP binding	5/3469	12/18639	0.416666666666667	2.2387575670222	0.0554759570474874	0.352574684363415
GO:0016801	hydrolase activity, acting on ether bonds	5/3469	12/18639	0.416666666666667	2.2387575670222	0.0554759570474874	0.352574684363415
GO:0016803	ether hydrolase activity	5/3469	12/18639	0.416666666666667	2.2387575670222	0.0554759570474874	0.352574684363415
GO:0035497	cAMP response element binding	5/3469	12/18639	0.416666666666667	2.2387575670222	0.0554759570474874	0.352574684363415
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	5/3469	12/18639	0.416666666666667	2.2387575670222	0.0554759570474874	0.352574684363415
GO:0097371	MDM2/MDM4 family protein binding	5/3469	12/18639	0.416666666666667	2.2387575670222	0.0554759570474874	0.352574684363415
GO:0141221	histone deacetylase activity, hydrolytic mechanism	5/3469	12/18639	0.416666666666667	2.2387575670222	0.0554759570474874	0.352574684363415
GO:0005126	cytokine receptor binding	62/3469	275/18639	0.225454545454545	1.21137136717419	0.0561325948813049	0.355065140263348
GO:0031369	translation initiation factor binding	10/3469	32/18639	0.3125	1.67906817526665	0.0598688149807283	0.368440502091432
GO:0005496	steroid binding	27/3469	108/18639	0.25	1.34325454021332	0.0600633547392083	0.368440502091432
GO:0005539	glycosaminoglycan binding	55/3469	242/18639	0.227272727272727	1.22114049110302	0.0604979591020885	0.368440502091432
GO:0017070	U6 snRNA binding	6/3469	16/18639	0.375	2.01488181031998	0.0606564480097136	0.368440502091432
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	6/3469	16/18639	0.375	2.01488181031998	0.0606564480097136	0.368440502091432
GO:0019789	SUMO transferase activity	9/3469	28/18639	0.321428571428571	1.72704155170284	0.0615886324545281	0.368440502091432
GO:0097718	disordered domain specific binding	9/3469	28/18639	0.321428571428571	1.72704155170284	0.0615886324545281	0.368440502091432
GO:0141110	transporter inhibitor activity	13/3469	45/18639	0.288888888888889	1.55220524646872	0.0622819426457645	0.368440502091432
GO:0000339	RNA cap binding	7/3469	20/18639	0.35	1.88055635629865	0.0625863081866362	0.368440502091432
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	7/3469	20/18639	0.35	1.88055635629865	0.0625863081866362	0.368440502091432
GO:0016408	C-acyltransferase activity	7/3469	20/18639	0.35	1.88055635629865	0.0625863081866362	0.368440502091432
GO:0042288	MHC class I protein binding	7/3469	20/18639	0.35	1.88055635629865	0.0625863081866362	0.368440502091432
GO:0001091	RNA polymerase II general transcription initiation factor binding	8/3469	24/18639	0.333333333333333	1.79100605361776	0.0626431278723687	0.368440502091432
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	8/3469	24/18639	0.333333333333333	1.79100605361776	0.0626431278723687	0.368440502091432
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	8/3469	24/18639	0.333333333333333	1.79100605361776	0.0626431278723687	0.368440502091432
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	8/3469	24/18639	0.333333333333333	1.79100605361776	0.0626431278723687	0.368440502091432
GO:0042169	SH2 domain binding	12/3469	41/18639	0.292682926829268	1.57259068122535	0.0655841012160329	0.382383824916088
GO:0061650	ubiquitin-like protein conjugating enzyme activity	12/3469	41/18639	0.292682926829268	1.57259068122535	0.0655841012160329	0.382383824916088
GO:0140311	protein sequestering activity	10/3469	33/18639	0.303030303030303	1.62818732147069	0.0721179058700524	0.418658492518356
GO:0030295	protein kinase activator activity	33/3469	139/18639	0.237410071942446	1.27560862811624	0.0764923595766941	0.43424987327916
GO:0005172	vascular endothelial growth factor receptor binding	5/3469	13/18639	0.384615384615385	2.06654544648203	0.0767466218994489	0.43424987327916
GO:0005542	folic acid binding	5/3469	13/18639	0.384615384615385	2.06654544648203	0.0767466218994489	0.43424987327916
GO:0019104	DNA N-glycosylase activity	5/3469	13/18639	0.384615384615385	2.06654544648203	0.0767466218994489	0.43424987327916
GO:0019855	calcium channel inhibitor activity	5/3469	13/18639	0.384615384615385	2.06654544648203	0.0767466218994489	0.43424987327916
GO:0032396	inhibitory MHC class I receptor activity	5/3469	13/18639	0.384615384615385	2.06654544648203	0.0767466218994489	0.43424987327916
GO:0016247	channel regulator activity	39/3469	168/18639	0.232142857142857	1.24730778734094	0.0776255726059974	0.435074024044522
GO:0120020	cholesterol transfer activity	8/3469	25/18639	0.32	1.71936581147305	0.0776614362571466	0.435074024044522
GO:0016830	carbon-carbon lyase activity	14/3469	51/18639	0.274509803921569	1.47494616180286	0.0788959180972024	0.435074024044522
GO:0030544	Hsp70 protein binding	14/3469	51/18639	0.274509803921569	1.47494616180286	0.0788959180972024	0.435074024044522
GO:0005123	death receptor binding	7/3469	21/18639	0.333333333333333	1.79100605361776	0.0793509940280108	0.435074024044522
GO:0016805	dipeptidase activity	6/3469	17/18639	0.352941176470588	1.89635935088939	0.0794877970849426	0.435074024044522
GO:0030169	low-density lipoprotein particle binding	6/3469	17/18639	0.352941176470588	1.89635935088939	0.0794877970849426	0.435074024044522
GO:0051787	misfolded protein binding	6/3469	17/18639	0.352941176470588	1.89635935088939	0.0794877970849426	0.435074024044522
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	21/3469	83/18639	0.253012048192771	1.35943832985444	0.0802707904865393	0.437573699359549
GO:0042887	amide transmembrane transporter activity	11/3469	38/18639	0.289473684210526	1.55534736235226	0.0813154407985892	0.439693573027855
GO:0043531	ADP binding	11/3469	38/18639	0.289473684210526	1.55534736235226	0.0813154407985892	0.439693573027855
GO:0016831	carboxy-lyase activity	10/3469	34/18639	0.294117647058824	1.58029945907449	0.0858292542032955	0.460388119546477
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	10/3469	34/18639	0.294117647058824	1.58029945907449	0.0858292542032955	0.460388119546477
GO:0051015	actin filament binding	47/3469	209/18639	0.22488038277512	1.20828638067035	0.0892849330821174	0.476716952805743
GO:0141108	transporter regulator activity	39/3469	170/18639	0.229411764705882	1.2326335780781	0.0895843938158444	0.476716952805743
GO:0008198	ferrous iron binding	8/3469	26/18639	0.307692307692308	1.65323635718562	0.0946418174333924	0.485409178130726
GO:0050681	nuclear androgen receptor binding	8/3469	26/18639	0.307692307692308	1.65323635718562	0.0946418174333924	0.485409178130726
GO:0070412	R-SMAD binding	8/3469	26/18639	0.307692307692308	1.65323635718562	0.0946418174333924	0.485409178130726
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	13/3469	48/18639	0.270833333333333	1.45519241856443	0.0964023616879062	0.485409178130726
GO:0140693	molecular condensate scaffold activity	13/3469	48/18639	0.270833333333333	1.45519241856443	0.0964023616879062	0.485409178130726
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	4/3469	10/18639	0.4	2.14920726434131	0.0976518176598541	0.485409178130726
GO:0008239	dipeptidyl-peptidase activity	4/3469	10/18639	0.4	2.14920726434131	0.0976518176598541	0.485409178130726
GO:0016175	superoxide-generating NAD(P)H oxidase activity	4/3469	10/18639	0.4	2.14920726434131	0.0976518176598541	0.485409178130726
GO:0016303	1-phosphatidylinositol-3-kinase activity	4/3469	10/18639	0.4	2.14920726434131	0.0976518176598541	0.485409178130726
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	4/3469	10/18639	0.4	2.14920726434131	0.0976518176598541	0.485409178130726
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	4/3469	10/18639	0.4	2.14920726434131	0.0976518176598541	0.485409178130726
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	4/3469	10/18639	0.4	2.14920726434131	0.0976518176598541	0.485409178130726
GO:0098505	G-rich strand telomeric DNA binding	4/3469	10/18639	0.4	2.14920726434131	0.0976518176598541	0.485409178130726
GO:0008970	phospholipase A1 activity	7/3469	22/18639	0.318181818181818	1.70959668754422	0.0984572250977618	0.485409178130726
GO:0034062	5'-3' RNA polymerase activity	7/3469	22/18639	0.318181818181818	1.70959668754422	0.0984572250977618	0.485409178130726
GO:0070034	telomerase RNA binding	7/3469	22/18639	0.318181818181818	1.70959668754422	0.0984572250977618	0.485409178130726
GO:0097747	RNA polymerase activity	7/3469	22/18639	0.318181818181818	1.70959668754422	0.0984572250977618	0.485409178130726
GO:0061631	ubiquitin conjugating enzyme activity	10/3469	35/18639	0.285714285714286	1.53514804595808	0.101009798751707	0.485409178130726
GO:0008083	growth factor activity	37/3469	162/18639	0.228395061728395	1.22717081451587	0.101038824851447	0.485409178130726
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	6/3469	18/18639	0.333333333333333	1.79100605361776	0.101204472481131	0.485409178130726
GO:0008308	voltage-gated monoatomic anion channel activity	6/3469	18/18639	0.333333333333333	1.79100605361776	0.101204472481131	0.485409178130726
GO:0016854	racemase and epimerase activity	6/3469	18/18639	0.333333333333333	1.79100605361776	0.101204472481131	0.485409178130726
GO:0005347	ATP transmembrane transporter activity	5/3469	14/18639	0.357142857142857	1.9189350574476	0.101756916149486	0.485409178130726
GO:0008474	palmitoyl-(protein) hydrolase activity	5/3469	14/18639	0.357142857142857	1.9189350574476	0.101756916149486	0.485409178130726
GO:0032036	myosin heavy chain binding	5/3469	14/18639	0.357142857142857	1.9189350574476	0.101756916149486	0.485409178130726
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	5/3469	14/18639	0.357142857142857	1.9189350574476	0.101756916149486	0.485409178130726
GO:0061665	SUMO ligase activity	5/3469	14/18639	0.357142857142857	1.9189350574476	0.101756916149486	0.485409178130726
GO:0071933	Arp2/3 complex binding	5/3469	14/18639	0.357142857142857	1.9189350574476	0.101756916149486	0.485409178130726
GO:0098599	palmitoyl hydrolase activity	5/3469	14/18639	0.357142857142857	1.9189350574476	0.101756916149486	0.485409178130726
GO:0004864	protein phosphatase inhibitor activity	14/3469	53/18639	0.264150943396226	1.41928781607445	0.102596765280972	0.485409178130726
GO:0003924	GTPase activity	71/3469	331/18639	0.214501510574018	1.15252051184466	0.103863976412694	0.485409178130726
GO:0033192	calmodulin-dependent protein phosphatase activity	20/3469	81/18639	0.246913580246914	1.32667115082797	0.10533487758094	0.485409178130726
GO:0140791	histone H2AXS140 phosphatase activity	20/3469	81/18639	0.246913580246914	1.32667115082797	0.10533487758094	0.485409178130726
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	20/3469	81/18639	0.246913580246914	1.32667115082797	0.10533487758094	0.485409178130726
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	20/3469	81/18639	0.246913580246914	1.32667115082797	0.10533487758094	0.485409178130726
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	20/3469	81/18639	0.246913580246914	1.32667115082797	0.10533487758094	0.485409178130726
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	20/3469	81/18639	0.246913580246914	1.32667115082797	0.10533487758094	0.485409178130726
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	20/3469	81/18639	0.246913580246914	1.32667115082797	0.10533487758094	0.485409178130726
GO:1990439	MAP kinase serine/threonine phosphatase activity	20/3469	81/18639	0.246913580246914	1.32667115082797	0.10533487758094	0.485409178130726
GO:0005164	tumor necrosis factor receptor binding	9/3469	31/18639	0.290322580645161	1.55990849831224	0.107214671068934	0.492379705148767
GO:0016763	pentosyltransferase activity	13/3469	49/18639	0.26530612244898	1.42549461410393	0.109893971912389	0.502961830493222
GO:0004364	glutathione transferase activity	8/3469	27/18639	0.296296296296296	1.59200538099356	0.113557445517737	0.51796100149417
GO:0031267	small GTPase binding	61/3469	283/18639	0.215547703180212	1.15814172371749	0.115297983007886	0.524007280414701
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	20/3469	82/18639	0.24390243902439	1.31049223435446	0.116055303716008	0.524007280414701
GO:0033549	MAP kinase phosphatase activity	20/3469	82/18639	0.24390243902439	1.31049223435446	0.116055303716008	0.524007280414701
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	30/3469	130/18639	0.230769230769231	1.23992726788922	0.116766491892786	0.524090583744107
GO:0005484	SNAP receptor activity	10/3469	36/18639	0.277777777777778	1.49250504468146	0.11764564867542	0.524090583744107
GO:0004715	non-membrane spanning protein tyrosine kinase activity	12/3469	45/18639	0.266666666666667	1.43280484289421	0.117800061676911	0.524090583744107
GO:0008009	chemokine activity	12/3469	45/18639	0.266666666666667	1.43280484289421	0.117800061676911	0.524090583744107
GO:0017134	fibroblast growth factor binding	7/3469	23/18639	0.304347826086957	1.63526639678143	0.119842949506117	0.524090583744107
GO:0031681	G-protein beta-subunit binding	7/3469	23/18639	0.304347826086957	1.63526639678143	0.119842949506117	0.524090583744107
GO:0043274	phospholipase binding	7/3469	23/18639	0.304347826086957	1.63526639678143	0.119842949506117	0.524090583744107
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	7/3469	23/18639	0.304347826086957	1.63526639678143	0.119842949506117	0.524090583744107
GO:0004521	RNA endonuclease activity	18/3469	73/18639	0.246575342465753	1.32485379308711	0.120988830309966	0.524090583744107
GO:0045309	protein phosphorylated amino acid binding	15/3469	59/18639	0.254237288135593	1.36602156631863	0.121160277052883	0.524090583744107
GO:0042277	peptide binding	54/3469	249/18639	0.216867469879518	1.16523285416095	0.121426026796855	0.524090583744107
GO:0099106	ion channel regulator activity	36/3469	160/18639	0.225	1.20892908619199	0.122822659699125	0.524090583744107
GO:0003756	protein disulfide isomerase activity	6/3469	19/18639	0.315789473684211	1.69674257711156	0.125681653256341	0.524090583744107
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	6/3469	19/18639	0.315789473684211	1.69674257711156	0.125681653256341	0.524090583744107
GO:0070003	threonine-type peptidase activity	6/3469	19/18639	0.315789473684211	1.69674257711156	0.125681653256341	0.524090583744107
GO:0097001	ceramide binding	6/3469	19/18639	0.315789473684211	1.69674257711156	0.125681653256341	0.524090583744107
GO:0022884	macromolecule transmembrane transporter activity	9/3469	32/18639	0.28125	1.51116135773998	0.125741310407797	0.524090583744107
GO:0051059	NF-kappaB binding	9/3469	32/18639	0.28125	1.51116135773998	0.125741310407797	0.524090583744107
GO:0019902	phosphatase binding	42/3469	190/18639	0.221052631578947	1.18771980397809	0.126120551939522	0.524090583744107
GO:0001530	lipopolysaccharide binding	11/3469	41/18639	0.268292682926829	1.4415414577899	0.126378975704292	0.524090583744107
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	11/3469	41/18639	0.268292682926829	1.4415414577899	0.126378975704292	0.524090583744107
GO:0017080	sodium channel regulator activity	11/3469	41/18639	0.268292682926829	1.4415414577899	0.126378975704292	0.524090583744107
GO:0042287	MHC protein binding	11/3469	41/18639	0.268292682926829	1.4415414577899	0.126378975704292	0.524090583744107
GO:0140318	protein transporter activity	11/3469	41/18639	0.268292682926829	1.4415414577899	0.126378975704292	0.524090583744107
GO:0000287	magnesium ion binding	50/3469	230/18639	0.217391304347826	1.16804742627245	0.127835111519018	0.524090583744107
GO:0140313	molecular sequestering activity	14/3469	55/18639	0.254545454545455	1.36767735003538	0.130171809523945	0.524090583744107
GO:0141050	histone H3K deacetylase activity	5/3469	15/18639	0.333333333333333	1.79100605361776	0.130259117468935	0.524090583744107
GO:0141051	histone H4K deacetylase activity	5/3469	15/18639	0.333333333333333	1.79100605361776	0.130259117468935	0.524090583744107
GO:0001851	complement component C3b binding	4/3469	11/18639	0.363636363636364	1.95382478576483	0.131706582193709	0.524090583744107
GO:0005225	volume-sensitive anion channel activity	4/3469	11/18639	0.363636363636364	1.95382478576483	0.131706582193709	0.524090583744107
GO:0008046	axon guidance receptor activity	4/3469	11/18639	0.363636363636364	1.95382478576483	0.131706582193709	0.524090583744107
GO:0010854	adenylate cyclase regulator activity	4/3469	11/18639	0.363636363636364	1.95382478576483	0.131706582193709	0.524090583744107
GO:0015217	ADP transmembrane transporter activity	4/3469	11/18639	0.363636363636364	1.95382478576483	0.131706582193709	0.524090583744107
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	4/3469	11/18639	0.363636363636364	1.95382478576483	0.131706582193709	0.524090583744107
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	4/3469	11/18639	0.363636363636364	1.95382478576483	0.131706582193709	0.524090583744107
GO:0032794	GTPase activating protein binding	4/3469	11/18639	0.363636363636364	1.95382478576483	0.131706582193709	0.524090583744107
GO:0034713	type I transforming growth factor beta receptor binding	4/3469	11/18639	0.363636363636364	1.95382478576483	0.131706582193709	0.524090583744107
GO:0097493	structural molecule activity conferring elasticity	4/3469	11/18639	0.363636363636364	1.95382478576483	0.131706582193709	0.524090583744107
GO:0140031	phosphorylation-dependent protein binding	4/3469	11/18639	0.363636363636364	1.95382478576483	0.131706582193709	0.524090583744107
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	4/3469	11/18639	0.363636363636364	1.95382478576483	0.131706582193709	0.524090583744107
GO:0051219	phosphoprotein binding	22/3469	93/18639	0.236559139784946	1.27103655418034	0.132548182841235	0.525879033106795
GO:0051019	mitogen-activated protein kinase binding	8/3469	28/18639	0.285714285714286	1.53514804595808	0.134344970743021	0.529905678356818
GO:0003713	transcription coactivator activity	55/3469	256/18639	0.21484375	1.15435937049582	0.134515013537114	0.529905678356818
GO:0001098	basal transcription machinery binding	15/3469	60/18639	0.25	1.34325454021332	0.135143730050732	0.529905678356818
GO:0001099	basal RNA polymerase II transcription machinery binding	15/3469	60/18639	0.25	1.34325454021332	0.135143730050732	0.529905678356818
GO:0043394	proteoglycan binding	10/3469	37/18639	0.27027027027027	1.45216707050088	0.135702471857681	0.530545232539797
GO:0020037	heme binding	32/3469	142/18639	0.225352112676056	1.2108209939951	0.136905544477775	0.533692834722952
GO:0017018	myosin phosphatase activity	20/3469	84/18639	0.238095238095238	1.2792900382984	0.139409811850058	0.53900143994863
GO:0051117	ATPase binding	20/3469	84/18639	0.238095238095238	1.2792900382984	0.139409811850058	0.53900143994863
GO:0120013	lipid transfer activity	16/3469	65/18639	0.246153846153846	1.3225890857485	0.139473154110496	0.53900143994863
GO:0005021	vascular endothelial growth factor receptor activity	13/3469	51/18639	0.254901960784314	1.36959286453123	0.140020333400053	0.539561112326067
GO:0008201	heparin binding	38/3469	172/18639	0.22093023255814	1.18706215181642	0.140576206973679	0.540150984388836
GO:0005540	hyaluronic acid binding	7/3469	24/18639	0.291666666666667	1.56713029691554	0.143395817237661	0.546289178737793
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	7/3469	24/18639	0.291666666666667	1.56713029691554	0.143395817237661	0.546289178737793
GO:0050431	transforming growth factor beta binding	7/3469	24/18639	0.291666666666667	1.56713029691554	0.143395817237661	0.546289178737793
GO:0051879	Hsp90 protein binding	11/3469	42/18639	0.261904761904762	1.40721904212824	0.143940313200303	0.546810084990385
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	9/3469	33/18639	0.272727272727273	1.46536858932362	0.145850087109451	0.552499906253597
GO:0016836	hydro-lyase activity	15/3469	61/18639	0.245901639344262	1.32123397398031	0.149992172302675	0.566590149458839
GO:0001784	phosphotyrosine residue binding	12/3469	47/18639	0.25531914893617	1.37183442404764	0.15081858797154	0.568111591207402
GO:0030742	GTP-dependent protein binding	6/3469	20/18639	0.3	1.61190544825598	0.152722515429072	0.573671969720967
GO:0003785	actin monomer binding	8/3469	29/18639	0.275862068965517	1.48221190644228	0.156907326852351	0.586107869941511
GO:0051861	glycolipid binding	8/3469	29/18639	0.275862068965517	1.48221190644228	0.156907326852351	0.586107869941511
GO:0061135	endopeptidase regulator activity	40/3469	184/18639	0.217391304347826	1.16804742627245	0.158446276219657	0.586520590956626
GO:0098631	cell adhesion mediator activity	18/3469	76/18639	0.236842105263158	1.27255693283367	0.160404164447781	0.586520590956626
GO:0000062	fatty-acyl-CoA binding	5/3469	16/18639	0.3125	1.67906817526665	0.161896694495854	0.586520590956626
GO:0004708	MAP kinase kinase activity	5/3469	16/18639	0.3125	1.67906817526665	0.161896694495854	0.586520590956626
GO:0008142	oxysterol binding	5/3469	16/18639	0.3125	1.67906817526665	0.161896694495854	0.586520590956626
GO:0015923	mannosidase activity	5/3469	16/18639	0.3125	1.67906817526665	0.161896694495854	0.586520590956626
GO:0043023	ribosomal large subunit binding	5/3469	16/18639	0.3125	1.67906817526665	0.161896694495854	0.586520590956626
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	5/3469	16/18639	0.3125	1.67906817526665	0.161896694495854	0.586520590956626
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	5/3469	16/18639	0.3125	1.67906817526665	0.161896694495854	0.586520590956626
GO:0035401	histone H3Y41 kinase activity	26/3469	115/18639	0.226086956521739	1.21476932332335	0.162012776310036	0.586520590956626
GO:0140801	histone H2AXY142 kinase activity	26/3469	115/18639	0.226086956521739	1.21476932332335	0.162012776310036	0.586520590956626
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	11/3469	43/18639	0.255813953488372	1.3744930178927	0.162703698609892	0.586520590956626
GO:0048156	tau protein binding	11/3469	43/18639	0.255813953488372	1.3744930178927	0.162703698609892	0.586520590956626
GO:0016798	hydrolase activity, acting on glycosyl bonds	29/3469	130/18639	0.223076923076923	1.19859635895958	0.16466514591683	0.588452612098982
GO:0004713	protein tyrosine kinase activity	31/3469	140/18639	0.221428571428571	1.18973973561751	0.165856886631091	0.588452612098982
GO:0052866	phosphatidylinositol phosphate phosphatase activity	9/3469	34/18639	0.264705882352941	1.42226951316704	0.167457586955667	0.588452612098982
GO:0016407	acetyltransferase activity	22/3469	96/18639	0.229166666666667	1.23131666186221	0.168928617501093	0.588452612098982
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	7/3469	25/18639	0.28	1.50444508503892	0.168959187618972	0.588452612098982
GO:0008173	RNA methyltransferase activity	16/3469	67/18639	0.238805970149254	1.28310881453212	0.169244252323367	0.588452612098982
GO:0050840	extracellular matrix binding	16/3469	67/18639	0.238805970149254	1.28310881453212	0.169244252323367	0.588452612098982
GO:0004875	complement receptor activity	4/3469	12/18639	0.333333333333333	1.79100605361776	0.16982189476682	0.588452612098982
GO:0010853	cyclase activator activity	4/3469	12/18639	0.333333333333333	1.79100605361776	0.16982189476682	0.588452612098982
GO:0016273	arginine N-methyltransferase activity	4/3469	12/18639	0.333333333333333	1.79100605361776	0.16982189476682	0.588452612098982
GO:0016274	protein-arginine N-methyltransferase activity	4/3469	12/18639	0.333333333333333	1.79100605361776	0.16982189476682	0.588452612098982
GO:0035259	nuclear glucocorticoid receptor binding	4/3469	12/18639	0.333333333333333	1.79100605361776	0.16982189476682	0.588452612098982
GO:0043047	single-stranded telomeric DNA binding	4/3469	12/18639	0.333333333333333	1.79100605361776	0.16982189476682	0.588452612098982
GO:0070679	inositol 1,4,5 trisphosphate binding	4/3469	12/18639	0.333333333333333	1.79100605361776	0.16982189476682	0.588452612098982
GO:1990247	N6-methyladenosine-containing RNA reader activity	4/3469	12/18639	0.333333333333333	1.79100605361776	0.16982189476682	0.588452612098982
GO:0005518	collagen binding	17/3469	72/18639	0.236111111111111	1.26862928797924	0.172296177063839	0.595487560419093
GO:0001664	G protein-coupled receptor binding	62/3469	297/18639	0.208754208754209	1.12164015479092	0.174242570744053	0.600666548503279
GO:0008081	phosphoric diester hydrolase activity	20/3469	87/18639	0.229885057471264	1.2351765887019	0.179085692820858	0.615005988085426
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	8/3469	30/18639	0.266666666666667	1.43280484289421	0.181117470099644	0.615005988085426
GO:0015215	nucleotide transmembrane transporter activity	8/3469	30/18639	0.266666666666667	1.43280484289421	0.181117470099644	0.615005988085426
GO:0016769	transferase activity, transferring nitrogenous groups	8/3469	30/18639	0.266666666666667	1.43280484289421	0.181117470099644	0.615005988085426
GO:0033612	receptor serine/threonine kinase binding	8/3469	30/18639	0.266666666666667	1.43280484289421	0.181117470099644	0.615005988085426
GO:0001846	opsonin binding	6/3469	21/18639	0.285714285714286	1.53514804595808	0.182071123989496	0.615005988085426
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	6/3469	21/18639	0.285714285714286	1.53514804595808	0.182071123989496	0.615005988085426
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	6/3469	21/18639	0.285714285714286	1.53514804595808	0.182071123989496	0.615005988085426
GO:0030020	extracellular matrix structural constituent conferring tensile strength	11/3469	44/18639	0.25	1.34325454021332	0.182606521501432	0.615264686767387
GO:0030145	manganese ion binding	16/3469	68/18639	0.235294117647059	1.26423956725959	0.185264709249957	0.622656579208504
GO:1990782	protein tyrosine kinase binding	26/3469	117/18639	0.222222222222222	1.19400403574517	0.18587834259534	0.623157143550876
GO:0042826	histone deacetylase binding	28/3469	127/18639	0.220472440944882	1.1846024291645	0.186890072892586	0.62498650311461
GO:0019199	transmembrane receptor protein kinase activity	18/3469	78/18639	0.230769230769231	1.23992726788922	0.190072545373067	0.634047968520603
GO:0003712	transcription coregulator activity	100/3469	495/18639	0.202020202020202	1.08545821431379	0.193234199867717	0.63443605520302
GO:0042626	ATPase-coupled transmembrane transporter activity	22/3469	98/18639	0.224489795918367	1.20618775039563	0.195867656327956	0.63443605520302
GO:0004029	aldehyde dehydrogenase (NAD+) activity	5/3469	17/18639	0.294117647058824	1.58029945907449	0.196233735083734	0.63443605520302
GO:0005092	GDP-dissociation inhibitor activity	5/3469	17/18639	0.294117647058824	1.58029945907449	0.196233735083734	0.63443605520302
GO:0008429	phosphatidylethanolamine binding	5/3469	17/18639	0.294117647058824	1.58029945907449	0.196233735083734	0.63443605520302
GO:0016018	cyclosporin A binding	5/3469	17/18639	0.294117647058824	1.58029945907449	0.196233735083734	0.63443605520302
GO:0017110	nucleoside diphosphate phosphatase activity	5/3469	17/18639	0.294117647058824	1.58029945907449	0.196233735083734	0.63443605520302
GO:0048038	quinone binding	5/3469	17/18639	0.294117647058824	1.58029945907449	0.196233735083734	0.63443605520302
GO:0070402	NADPH binding	5/3469	17/18639	0.294117647058824	1.58029945907449	0.196233735083734	0.63443605520302
GO:1901567	fatty acid derivative binding	5/3469	17/18639	0.294117647058824	1.58029945907449	0.196233735083734	0.63443605520302
GO:0008157	protein phosphatase 1 binding	7/3469	26/18639	0.269230769230769	1.44658181253742	0.196339271371554	0.63443605520302
GO:0015216	purine nucleotide transmembrane transporter activity	7/3469	26/18639	0.269230769230769	1.44658181253742	0.196339271371554	0.63443605520302
GO:0050750	low-density lipoprotein particle receptor binding	7/3469	26/18639	0.269230769230769	1.44658181253742	0.196339271371554	0.63443605520302
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	10/3469	40/18639	0.25	1.34325454021332	0.197771232011802	0.635998134599104
GO:0140662	ATP-dependent protein folding chaperone	10/3469	40/18639	0.25	1.34325454021332	0.197771232011802	0.635998134599104
GO:0048029	monosaccharide binding	17/3469	74/18639	0.22972972972973	1.23434200992575	0.204110256878459	0.654813048980893
GO:0016835	carbon-oxygen lyase activity	18/3469	79/18639	0.227848101265823	1.2242319860172	0.205851988981703	0.657085901418234
GO:0016411	acylglycerol O-acyltransferase activity	8/3469	31/18639	0.258064516129032	1.3865853318331	0.20682279150163	0.657085901418234
GO:0017147	Wnt-protein binding	8/3469	31/18639	0.258064516129032	1.3865853318331	0.20682279150163	0.657085901418234
GO:0070325	lipoprotein particle receptor binding	8/3469	31/18639	0.258064516129032	1.3865853318331	0.20682279150163	0.657085901418234
GO:0005006	epidermal growth factor receptor activity	12/3469	50/18639	0.24	1.28952435860479	0.208220407592886	0.657085901418234
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	4/3469	13/18639	0.307692307692308	1.65323635718562	0.211188682707874	0.657085901418234
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	4/3469	13/18639	0.307692307692308	1.65323635718562	0.211188682707874	0.657085901418234
GO:0008253	5'-nucleotidase activity	4/3469	13/18639	0.307692307692308	1.65323635718562	0.211188682707874	0.657085901418234
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	4/3469	13/18639	0.307692307692308	1.65323635718562	0.211188682707874	0.657085901418234
GO:0017154	semaphorin receptor activity	4/3469	13/18639	0.307692307692308	1.65323635718562	0.211188682707874	0.657085901418234
GO:0031432	titin binding	4/3469	13/18639	0.307692307692308	1.65323635718562	0.211188682707874	0.657085901418234
GO:0039706	co-receptor binding	4/3469	13/18639	0.307692307692308	1.65323635718562	0.211188682707874	0.657085901418234
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	4/3469	13/18639	0.307692307692308	1.65323635718562	0.211188682707874	0.657085901418234
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	6/3469	22/18639	0.272727272727273	1.46536858932362	0.213426336073897	0.660980869919389
GO:0031683	G-protein beta/gamma-subunit complex binding	6/3469	22/18639	0.272727272727273	1.46536858932362	0.213426336073897	0.660980869919389
GO:0004714	transmembrane receptor protein tyrosine kinase activity	14/3469	60/18639	0.233333333333333	1.25370423753243	0.214990100122762	0.664289687245676
GO:0160215	deacylase activity	15/3469	65/18639	0.230769230769231	1.23992726788922	0.217434380741563	0.670297711665371
GO:0017124	SH3 domain binding	25/3469	115/18639	0.217391304347826	1.16804742627245	0.225004777869143	0.6920445117489
GO:0000900	mRNA regulatory element binding translation repressor activity	5/3469	18/18639	0.277777777777778	1.49250504468146	0.232783451469351	0.707851719774148
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	5/3469	18/18639	0.277777777777778	1.49250504468146	0.232783451469351	0.707851719774148
GO:0031690	adrenergic receptor binding	5/3469	18/18639	0.277777777777778	1.49250504468146	0.232783451469351	0.707851719774148
GO:0035615	clathrin adaptor activity	5/3469	18/18639	0.277777777777778	1.49250504468146	0.232783451469351	0.707851719774148
GO:0070628	proteasome binding	5/3469	18/18639	0.277777777777778	1.49250504468146	0.232783451469351	0.707851719774148
GO:0071813	lipoprotein particle binding	8/3469	32/18639	0.25	1.34325454021332	0.233849951866241	0.707884391540924
GO:0071814	protein-lipid complex binding	8/3469	32/18639	0.25	1.34325454021332	0.233849951866241	0.707884391540924
GO:0030971	receptor tyrosine kinase binding	18/3469	81/18639	0.222222222222222	1.19400403574517	0.239139049759047	0.72170925312991
GO:0008234	cysteine-type peptidase activity	39/3469	187/18639	0.20855614973262	1.120575980071	0.239493376318277	0.72170925312991
GO:0019213	deacetylase activity	9/3469	37/18639	0.243243243243243	1.3069503634508	0.240131409900748	0.722009463401127
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	35/3469	167/18639	0.209580838323353	1.12608165047823	0.243936274574284	0.729574355512397
GO:0030246	carbohydrate binding	57/3469	280/18639	0.203571428571429	1.09379298274513	0.245954693811594	0.729574355512397
GO:0004602	glutathione peroxidase activity	6/3469	23/18639	0.260869565217391	1.40165691152694	0.24645576662723	0.729574355512397
GO:0005158	insulin receptor binding	6/3469	23/18639	0.260869565217391	1.40165691152694	0.24645576662723	0.729574355512397
GO:0016849	phosphorus-oxygen lyase activity	6/3469	23/18639	0.260869565217391	1.40165691152694	0.24645576662723	0.729574355512397
GO:0042171	lysophosphatidic acid acyltransferase activity	6/3469	23/18639	0.260869565217391	1.40165691152694	0.24645576662723	0.729574355512397
GO:0071617	lysophospholipid acyltransferase activity	6/3469	23/18639	0.260869565217391	1.40165691152694	0.24645576662723	0.729574355512397
GO:0046906	tetrapyrrole binding	32/3469	152/18639	0.210526315789474	1.13116171807437	0.247123993683654	0.729941135528151
GO:0043495	protein-membrane adaptor activity	11/3469	47/18639	0.234042553191489	1.25751488871034	0.248341865305772	0.731926244780309
GO:0005161	platelet-derived growth factor receptor binding	4/3469	14/18639	0.285714285714286	1.53514804595808	0.254961389331229	0.743267876289518
GO:0008494	translation activator activity	4/3469	14/18639	0.285714285714286	1.53514804595808	0.254961389331229	0.743267876289518
GO:0031404	chloride ion binding	4/3469	14/18639	0.285714285714286	1.53514804595808	0.254961389331229	0.743267876289518
GO:0042043	neurexin family protein binding	4/3469	14/18639	0.285714285714286	1.53514804595808	0.254961389331229	0.743267876289518
GO:0098847	sequence-specific single stranded DNA binding	4/3469	14/18639	0.285714285714286	1.53514804595808	0.254961389331229	0.743267876289518
GO:0046966	nuclear thyroid hormone receptor binding	7/3469	28/18639	0.25	1.34325454021332	0.255635556979513	0.743616663578148
GO:0019956	chemokine binding	8/3469	33/18639	0.242424242424242	1.30254985717655	0.262009908588414	0.753129960848507
GO:0043177	organic acid binding	39/3469	189/18639	0.206349206349206	1.10871803319194	0.262356451798266	0.753129960848507
GO:0016741	transferase activity, transferring one-carbon groups	44/3469	215/18639	0.204651162790698	1.09959441431416	0.265858466970157	0.753129960848507
GO:0005109	frizzled binding	9/3469	38/18639	0.236842105263158	1.27255693283367	0.266512271466677	0.753129960848507
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	5/3469	19/18639	0.263157894736842	1.41395214759297	0.271034093688283	0.753129960848507
GO:0005346	purine ribonucleotide transmembrane transporter activity	5/3469	19/18639	0.263157894736842	1.41395214759297	0.271034093688283	0.753129960848507
GO:0120227	acyl-CoA binding	5/3469	19/18639	0.263157894736842	1.41395214759297	0.271034093688283	0.753129960848507
GO:0016879	ligase activity, forming carbon-nitrogen bonds	11/3469	48/18639	0.229166666666667	1.23131666186221	0.271942673079734	0.753129960848507
GO:0005246	calcium channel regulator activity	12/3469	53/18639	0.226415094339623	1.2165324137781	0.273469630472341	0.753129960848507
GO:0034212	protein N-acetyltransferase activity	12/3469	53/18639	0.226415094339623	1.2165324137781	0.273469630472341	0.753129960848507
GO:1901505	carbohydrate derivative transmembrane transporter activity	12/3469	53/18639	0.226415094339623	1.2165324137781	0.273469630472341	0.753129960848507
GO:0019903	protein phosphatase binding	30/3469	144/18639	0.208333333333333	1.1193787835111	0.276003622849763	0.753129960848507
GO:0070851	growth factor receptor binding	29/3469	139/18639	0.20863309352518	1.12098940046579	0.277521278086434	0.753129960848507
GO:0005345	purine nucleobase transmembrane transporter activity	3/3469	10/18639	0.3	1.61190544825598	0.280688807994876	0.753129960848507
GO:0005381	iron ion transmembrane transporter activity	3/3469	10/18639	0.3	1.61190544825598	0.280688807994876	0.753129960848507
GO:0008190	eukaryotic initiation factor 4E binding	3/3469	10/18639	0.3	1.61190544825598	0.280688807994876	0.753129960848507
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	3/3469	10/18639	0.3	1.61190544825598	0.280688807994876	0.753129960848507
GO:0015279	store-operated calcium channel activity	3/3469	10/18639	0.3	1.61190544825598	0.280688807994876	0.753129960848507
GO:0015924	mannosyl-oligosaccharide mannosidase activity	3/3469	10/18639	0.3	1.61190544825598	0.280688807994876	0.753129960848507
GO:0016783	sulfurtransferase activity	3/3469	10/18639	0.3	1.61190544825598	0.280688807994876	0.753129960848507
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	3/3469	10/18639	0.3	1.61190544825598	0.280688807994876	0.753129960848507
GO:0032395	MHC class II receptor activity	3/3469	10/18639	0.3	1.61190544825598	0.280688807994876	0.753129960848507
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	3/3469	10/18639	0.3	1.61190544825598	0.280688807994876	0.753129960848507
GO:0043208	glycosphingolipid binding	3/3469	10/18639	0.3	1.61190544825598	0.280688807994876	0.753129960848507
GO:0043295	glutathione binding	3/3469	10/18639	0.3	1.61190544825598	0.280688807994876	0.753129960848507
GO:0050308	sugar-phosphatase activity	3/3469	10/18639	0.3	1.61190544825598	0.280688807994876	0.753129960848507
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	3/3469	10/18639	0.3	1.61190544825598	0.280688807994876	0.753129960848507
GO:0050815	phosphoserine residue binding	3/3469	10/18639	0.3	1.61190544825598	0.280688807994876	0.753129960848507
GO:0051880	G-quadruplex DNA binding	3/3469	10/18639	0.3	1.61190544825598	0.280688807994876	0.753129960848507
GO:0071723	lipopeptide binding	3/3469	10/18639	0.3	1.61190544825598	0.280688807994876	0.753129960848507
GO:0140940	histone H2A methyltransferase activity	3/3469	10/18639	0.3	1.61190544825598	0.280688807994876	0.753129960848507
GO:0141109	transporter activator activity	3/3469	10/18639	0.3	1.61190544825598	0.280688807994876	0.753129960848507
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	3/3469	10/18639	0.3	1.61190544825598	0.280688807994876	0.753129960848507
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	3/3469	10/18639	0.3	1.61190544825598	0.280688807994876	0.753129960848507
GO:1905394	retromer complex binding	3/3469	10/18639	0.3	1.61190544825598	0.280688807994876	0.753129960848507
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	3/3469	10/18639	0.3	1.61190544825598	0.280688807994876	0.753129960848507
GO:1990259	histone H2AQ104 methyltransferase activity	3/3469	10/18639	0.3	1.61190544825598	0.280688807994876	0.753129960848507
GO:0004622	lysophospholipase activity	6/3469	24/18639	0.25	1.34325454021332	0.28080908309042	0.753129960848507
GO:0015295	solute:proton symporter activity	6/3469	24/18639	0.25	1.34325454021332	0.28080908309042	0.753129960848507
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	7/3469	29/18639	0.241379310344828	1.296935418137	0.287049084747245	0.764277041955657
GO:0097472	cyclin-dependent protein kinase activity	7/3469	29/18639	0.241379310344828	1.296935418137	0.287049084747245	0.764277041955657
GO:0099604	ligand-gated calcium channel activity	7/3469	29/18639	0.241379310344828	1.296935418137	0.287049084747245	0.764277041955657
GO:0030332	cyclin binding	8/3469	34/18639	0.235294117647059	1.26423956725959	0.29110293062926	0.764277041955657
GO:0016790	thiolester hydrolase activity	10/3469	44/18639	0.227272727272727	1.22114049110302	0.295320475932383	0.764277041955657
GO:0030547	signaling receptor inhibitor activity	10/3469	44/18639	0.227272727272727	1.22114049110302	0.295320475932383	0.764277041955657
GO:0001222	transcription corepressor binding	11/3469	49/18639	0.224489795918367	1.20618775039563	0.29620915339998	0.764277041955657
GO:0005004	GPI-linked ephrin receptor activity	11/3469	49/18639	0.224489795918367	1.20618775039563	0.29620915339998	0.764277041955657
GO:0005008	hepatocyte growth factor receptor activity	11/3469	49/18639	0.224489795918367	1.20618775039563	0.29620915339998	0.764277041955657
GO:0005009	insulin receptor activity	11/3469	49/18639	0.224489795918367	1.20618775039563	0.29620915339998	0.764277041955657
GO:0005011	macrophage colony-stimulating factor receptor activity	11/3469	49/18639	0.224489795918367	1.20618775039563	0.29620915339998	0.764277041955657
GO:0005018	platelet-derived growth factor alpha-receptor activity	11/3469	49/18639	0.224489795918367	1.20618775039563	0.29620915339998	0.764277041955657
GO:0005020	stem cell factor receptor activity	11/3469	49/18639	0.224489795918367	1.20618775039563	0.29620915339998	0.764277041955657
GO:0008288	boss receptor activity	11/3469	49/18639	0.224489795918367	1.20618775039563	0.29620915339998	0.764277041955657
GO:0036332	placental growth factor receptor activity	11/3469	49/18639	0.224489795918367	1.20618775039563	0.29620915339998	0.764277041955657
GO:0038062	protein tyrosine kinase collagen receptor activity	11/3469	49/18639	0.224489795918367	1.20618775039563	0.29620915339998	0.764277041955657
GO:0060175	brain-derived neurotrophic factor receptor activity	11/3469	49/18639	0.224489795918367	1.20618775039563	0.29620915339998	0.764277041955657
GO:0070063	RNA polymerase binding	13/3469	59/18639	0.220338983050847	1.18388535747614	0.296521499686665	0.764277041955657
GO:0050661	NADP binding	12/3469	54/18639	0.222222222222222	1.19400403574517	0.296566154453139	0.764277041955657
GO:0140375	immune receptor activity	32/3469	156/18639	0.205128205128205	1.10215757145708	0.299795902262642	0.764277041955657
GO:0004559	alpha-mannosidase activity	4/3469	15/18639	0.266666666666667	1.43280484289421	0.300307670008427	0.764277041955657
GO:0004953	icosanoid receptor activity	4/3469	15/18639	0.266666666666667	1.43280484289421	0.300307670008427	0.764277041955657
GO:0005523	tropomyosin binding	4/3469	15/18639	0.266666666666667	1.43280484289421	0.300307670008427	0.764277041955657
GO:0008252	nucleotidase activity	4/3469	15/18639	0.266666666666667	1.43280484289421	0.300307670008427	0.764277041955657
GO:0061578	K63-linked deubiquitinase activity	4/3469	15/18639	0.266666666666667	1.43280484289421	0.300307670008427	0.764277041955657
GO:0120283	protein serine/threonine kinase binding	4/3469	15/18639	0.266666666666667	1.43280484289421	0.300307670008427	0.764277041955657
GO:0031406	carboxylic acid binding	38/3469	187/18639	0.203208556149733	1.09184326263329	0.300353468389732	0.764277041955657
GO:0008276	protein methyltransferase activity	20/3469	95/18639	0.210526315789474	1.13116171807437	0.308002245732595	0.781102399252596
GO:0016779	nucleotidyltransferase activity	28/3469	136/18639	0.205882352941176	1.10620962135214	0.308130625805088	0.781102399252596
GO:0016874	ligase activity	34/3469	167/18639	0.203592814371257	1.093907889036	0.309019720169504	0.781878197636425
GO:0010851	cyclase regulator activity	5/3469	20/18639	0.25	1.34325454021332	0.310471286441353	0.782597735183937
GO:0061608	nuclear import signal receptor activity	5/3469	20/18639	0.25	1.34325454021332	0.310471286441353	0.782597735183937
GO:0019003	GDP binding	16/3469	75/18639	0.213333333333333	1.14624387431536	0.314806543034938	0.782613870683995
GO:0001848	complement binding	6/3469	25/18639	0.24	1.28952435860479	0.316130102712983	0.782613870683995
GO:0003707	nuclear steroid receptor activity	6/3469	25/18639	0.24	1.28952435860479	0.316130102712983	0.782613870683995
GO:0008483	transaminase activity	6/3469	25/18639	0.24	1.28952435860479	0.316130102712983	0.782613870683995
GO:0003714	transcription corepressor activity	41/3469	204/18639	0.200980392156863	1.07987129703424	0.31826233443469	0.782613870683995
GO:0008168	methyltransferase activity	41/3469	204/18639	0.200980392156863	1.07987129703424	0.31826233443469	0.782613870683995
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	13/3469	60/18639	0.216666666666667	1.16415393485154	0.319072737863915	0.782613870683995
GO:0098531	ligand-modulated transcription factor activity	13/3469	60/18639	0.216666666666667	1.16415393485154	0.319072737863915	0.782613870683995
GO:0001968	fibronectin binding	7/3469	30/18639	0.233333333333333	1.25370423753243	0.319289141379124	0.782613870683995
GO:0008106	alcohol dehydrogenase (NADP+) activity	7/3469	30/18639	0.233333333333333	1.25370423753243	0.319289141379124	0.782613870683995
GO:0008374	O-acyltransferase activity	12/3469	55/18639	0.218181818181818	1.1722948714589	0.320175876720034	0.782613870683995
GO:0098632	cell-cell adhesion mediator activity	12/3469	55/18639	0.218181818181818	1.1722948714589	0.320175876720034	0.782613870683995
GO:0043015	gamma-tubulin binding	8/3469	35/18639	0.228571428571429	1.22811843676646	0.32092343024952	0.782613870683995
GO:0005007	fibroblast growth factor receptor activity	11/3469	50/18639	0.22	1.18206399538772	0.321026491960956	0.782613870683995
GO:0005017	platelet-derived growth factor receptor activity	11/3469	50/18639	0.22	1.18206399538772	0.321026491960956	0.782613870683995
GO:0005019	platelet-derived growth factor beta-receptor activity	11/3469	50/18639	0.22	1.18206399538772	0.321026491960956	0.782613870683995
GO:0015605	organophosphate ester transmembrane transporter activity	11/3469	50/18639	0.22	1.18206399538772	0.321026491960956	0.782613870683995
GO:0004177	aminopeptidase activity	9/3469	40/18639	0.225	1.20892908619199	0.321566176545027	0.782613870683995
GO:0030331	nuclear estrogen receptor binding	9/3469	40/18639	0.225	1.20892908619199	0.321566176545027	0.782613870683995
GO:0004519	endonuclease activity	26/3469	127/18639	0.204724409448819	1.09998796993847	0.328018963344373	0.792206610210135
GO:0001618	virus receptor activity	17/3469	81/18639	0.209876543209877	1.12767047820377	0.332851904058829	0.792206610210135
GO:0005200	structural constituent of cytoskeleton	23/3469	112/18639	0.205357142857143	1.10338765803237	0.335824815778999	0.792206610210135
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	3/3469	11/18639	0.272727272727273	1.46536858932362	0.336557142670314	0.792206610210135
GO:0008271	secondary active sulfate transmembrane transporter activity	3/3469	11/18639	0.272727272727273	1.46536858932362	0.336557142670314	0.792206610210135
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	3/3469	11/18639	0.272727272727273	1.46536858932362	0.336557142670314	0.792206610210135
GO:0015205	nucleobase transmembrane transporter activity	3/3469	11/18639	0.272727272727273	1.46536858932362	0.336557142670314	0.792206610210135
GO:0016176	superoxide-generating NADPH oxidase activator activity	3/3469	11/18639	0.272727272727273	1.46536858932362	0.336557142670314	0.792206610210135
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	3/3469	11/18639	0.272727272727273	1.46536858932362	0.336557142670314	0.792206610210135
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	3/3469	11/18639	0.272727272727273	1.46536858932362	0.336557142670314	0.792206610210135
GO:0019107	myristoyltransferase activity	3/3469	11/18639	0.272727272727273	1.46536858932362	0.336557142670314	0.792206610210135
GO:0019203	carbohydrate phosphatase activity	3/3469	11/18639	0.272727272727273	1.46536858932362	0.336557142670314	0.792206610210135
GO:0035252	UDP-xylosyltransferase activity	3/3469	11/18639	0.272727272727273	1.46536858932362	0.336557142670314	0.792206610210135
GO:0042285	xylosyltransferase activity	3/3469	11/18639	0.272727272727273	1.46536858932362	0.336557142670314	0.792206610210135
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	3/3469	11/18639	0.272727272727273	1.46536858932362	0.336557142670314	0.792206610210135
GO:0048185	activin binding	3/3469	11/18639	0.272727272727273	1.46536858932362	0.336557142670314	0.792206610210135
GO:1900750	oligopeptide binding	3/3469	11/18639	0.272727272727273	1.46536858932362	0.336557142670314	0.792206610210135
GO:0035091	phosphatidylinositol binding	56/3469	284/18639	0.197183098591549	1.05946836974572	0.337603310284501	0.792206610210135
GO:0008238	exopeptidase activity	21/3469	102/18639	0.205882352941176	1.10620962135214	0.341269672078233	0.792206610210135
GO:0015026	coreceptor activity	13/3469	61/18639	0.213114754098361	1.14506944411627	0.342018158429779	0.792206610210135
GO:0005010	insulin-like growth factor receptor activity	11/3469	51/18639	0.215686274509804	1.15888626998796	0.346277389653551	0.792206610210135
GO:0005030	neurotrophin receptor activity	11/3469	51/18639	0.215686274509804	1.15888626998796	0.346277389653551	0.792206610210135
GO:0005024	transforming growth factor beta receptor activity	4/3469	16/18639	0.25	1.34325454021332	0.346444661845951	0.792206610210135
GO:0005149	interleukin-1 receptor binding	4/3469	16/18639	0.25	1.34325454021332	0.346444661845951	0.792206610210135
GO:0005159	insulin-like growth factor receptor binding	4/3469	16/18639	0.25	1.34325454021332	0.346444661845951	0.792206610210135
GO:0005521	lamin binding	4/3469	16/18639	0.25	1.34325454021332	0.346444661845951	0.792206610210135
GO:0015562	efflux transmembrane transporter activity	4/3469	16/18639	0.25	1.34325454021332	0.346444661845951	0.792206610210135
GO:0004180	carboxypeptidase activity	10/3469	46/18639	0.217391304347826	1.16804742627245	0.348205250190956	0.792206610210135
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	10/3469	46/18639	0.217391304347826	1.16804742627245	0.348205250190956	0.792206610210135
GO:0003779	actin binding	86/3469	443/18639	0.194130925507901	1.0430689883372	0.349214562372957	0.792206610210135
GO:0009931	calcium-dependent protein serine/threonine kinase activity	5/3469	21/18639	0.238095238095238	1.2792900382984	0.350596337207558	0.792206610210135
GO:0009975	cyclase activity	5/3469	21/18639	0.238095238095238	1.2792900382984	0.350596337207558	0.792206610210135
GO:0070182	DNA polymerase binding	5/3469	21/18639	0.238095238095238	1.2792900382984	0.350596337207558	0.792206610210135
GO:0140312	cargo adaptor activity	5/3469	21/18639	0.238095238095238	1.2792900382984	0.350596337207558	0.792206610210135
GO:0044390	ubiquitin-like protein conjugating enzyme binding	8/3469	36/18639	0.222222222222222	1.19400403574517	0.351264474228609	0.792206610210135
GO:0005112	Notch binding	6/3469	26/18639	0.230769230769231	1.23992726788922	0.352067352115412	0.792206610210135
GO:0005160	transforming growth factor beta receptor binding	6/3469	26/18639	0.230769230769231	1.23992726788922	0.352067352115412	0.792206610210135
GO:0019865	immunoglobulin binding	6/3469	26/18639	0.230769230769231	1.23992726788922	0.352067352115412	0.792206610210135
GO:0030507	spectrin binding	6/3469	26/18639	0.230769230769231	1.23992726788922	0.352067352115412	0.792206610210135
GO:0034237	protein kinase A regulatory subunit binding	6/3469	26/18639	0.230769230769231	1.23992726788922	0.352067352115412	0.792206610210135
GO:0052742	phosphatidylinositol kinase activity	6/3469	26/18639	0.230769230769231	1.23992726788922	0.352067352115412	0.792206610210135
GO:0070006	metalloaminopeptidase activity	6/3469	26/18639	0.230769230769231	1.23992726788922	0.352067352115412	0.792206610210135
GO:0097602	cullin family protein binding	6/3469	26/18639	0.230769230769231	1.23992726788922	0.352067352115412	0.792206610210135
GO:0120014	phospholipid transfer activity	6/3469	26/18639	0.230769230769231	1.23992726788922	0.352067352115412	0.792206610210135
GO:0047499	calcium-independent phospholipase A2 activity	7/3469	31/18639	0.225806451612903	1.21326216535396	0.35209182676006	0.792206610210135
GO:0140272	exogenous protein binding	17/3469	82/18639	0.207317073170732	1.11391839920129	0.35280236988314	0.792475675064139
GO:0005543	phospholipid binding	96/3469	497/18639	0.193158953722334	1.03784656628152	0.359186618821944	0.805466983010413
GO:0016500	protein-hormone receptor activity	14/3469	67/18639	0.208955223880597	1.12272021271561	0.362063038422548	0.808748894097588
GO:0019842	vitamin binding	30/3469	150/18639	0.2	1.07460363217065	0.362237521911427	0.808748894097588
GO:0008170	N-methyltransferase activity	20/3469	98/18639	0.204081632653061	1.09653431854148	0.362459422336056	0.808748894097588
GO:0015932	nucleobase-containing compound transmembrane transporter activity	12/3469	57/18639	0.210526315789474	1.13116171807437	0.368531319248956	0.818913889354348
GO:0005504	fatty acid binding	10/3469	47/18639	0.212765957446809	1.14319535337304	0.375195354213978	0.818913889354348
GO:0061733	protein-lysine-acetyltransferase activity	10/3469	47/18639	0.212765957446809	1.14319535337304	0.375195354213978	0.818913889354348
GO:0043425	bHLH transcription factor binding	7/3469	32/18639	0.21875	1.17534772268665	0.385199551730329	0.818913889354348
GO:0047498	calcium-dependent phospholipase A2 activity	7/3469	32/18639	0.21875	1.17534772268665	0.385199551730329	0.818913889354348
GO:0140142	nucleocytoplasmic carrier activity	7/3469	32/18639	0.21875	1.17534772268665	0.385199551730329	0.818913889354348
GO:0001221	transcription coregulator binding	23/3469	115/18639	0.2	1.07460363217065	0.387229395570224	0.818913889354348
GO:0008320	protein transmembrane transporter activity	6/3469	27/18639	0.222222222222222	1.19400403574517	0.388282906885418	0.818913889354348
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	6/3469	27/18639	0.222222222222222	1.19400403574517	0.388282906885418	0.818913889354348
GO:0035255	ionotropic glutamate receptor binding	6/3469	27/18639	0.222222222222222	1.19400403574517	0.388282906885418	0.818913889354348
GO:0004407	histone deacetylase activity	5/3469	22/18639	0.227272727272727	1.22114049110302	0.390940455188047	0.818913889354348
GO:0016881	acid-amino acid ligase activity	5/3469	22/18639	0.227272727272727	1.22114049110302	0.390940455188047	0.818913889354348
GO:0030021	extracellular matrix structural constituent conferring compression resistance	5/3469	22/18639	0.227272727272727	1.22114049110302	0.390940455188047	0.818913889354348
GO:0033558	protein lysine deacetylase activity	5/3469	22/18639	0.227272727272727	1.22114049110302	0.390940455188047	0.818913889354348
GO:0000340	RNA 7-methylguanosine cap binding	3/3469	12/18639	0.25	1.34325454021332	0.392135558638144	0.818913889354348
GO:0000995	RNA polymerase III general transcription initiation factor activity	3/3469	12/18639	0.25	1.34325454021332	0.392135558638144	0.818913889354348
GO:0004032	aldose reductase (NADPH) activity	3/3469	12/18639	0.25	1.34325454021332	0.392135558638144	0.818913889354348
GO:0004859	phospholipase inhibitor activity	3/3469	12/18639	0.25	1.34325454021332	0.392135558638144	0.818913889354348
GO:0005025	transforming growth factor beta receptor activity, type I	3/3469	12/18639	0.25	1.34325454021332	0.392135558638144	0.818913889354348
GO:0005026	transforming growth factor beta receptor activity, type II	3/3469	12/18639	0.25	1.34325454021332	0.392135558638144	0.818913889354348
GO:0005165	neurotrophin receptor binding	3/3469	12/18639	0.25	1.34325454021332	0.392135558638144	0.818913889354348
GO:0005247	voltage-gated chloride channel activity	3/3469	12/18639	0.25	1.34325454021332	0.392135558638144	0.818913889354348
GO:0008179	adenylate cyclase binding	3/3469	12/18639	0.25	1.34325454021332	0.392135558638144	0.818913889354348
GO:0008603	cAMP-dependent protein kinase regulator activity	3/3469	12/18639	0.25	1.34325454021332	0.392135558638144	0.818913889354348
GO:0015368	calcium:monoatomic cation antiporter activity	3/3469	12/18639	0.25	1.34325454021332	0.392135558638144	0.818913889354348
GO:0016361	activin receptor activity, type I	3/3469	12/18639	0.25	1.34325454021332	0.392135558638144	0.818913889354348
GO:0016362	activin receptor activity, type II	3/3469	12/18639	0.25	1.34325454021332	0.392135558638144	0.818913889354348
GO:0016423	tRNA (guanine) methyltransferase activity	3/3469	12/18639	0.25	1.34325454021332	0.392135558638144	0.818913889354348
GO:0016840	carbon-nitrogen lyase activity	3/3469	12/18639	0.25	1.34325454021332	0.392135558638144	0.818913889354348
GO:0017002	activin receptor activity	3/3469	12/18639	0.25	1.34325454021332	0.392135558638144	0.818913889354348
GO:0017166	vinculin binding	3/3469	12/18639	0.25	1.34325454021332	0.392135558638144	0.818913889354348
GO:0031543	peptidyl-proline dioxygenase activity	3/3469	12/18639	0.25	1.34325454021332	0.392135558638144	0.818913889354348
GO:0034452	dynactin binding	3/3469	12/18639	0.25	1.34325454021332	0.392135558638144	0.818913889354348
GO:0036009	protein-glutamine N-methyltransferase activity	3/3469	12/18639	0.25	1.34325454021332	0.392135558638144	0.818913889354348
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	3/3469	12/18639	0.25	1.34325454021332	0.392135558638144	0.818913889354348
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	3/3469	12/18639	0.25	1.34325454021332	0.392135558638144	0.818913889354348
GO:1990817	poly(A) RNA polymerase activity	3/3469	12/18639	0.25	1.34325454021332	0.392135558638144	0.818913889354348
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	4/3469	17/18639	0.235294117647059	1.26423956725959	0.392663408542018	0.818913889354348
GO:0004659	prenyltransferase activity	4/3469	17/18639	0.235294117647059	1.26423956725959	0.392663408542018	0.818913889354348
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	4/3469	17/18639	0.235294117647059	1.26423956725959	0.392663408542018	0.818913889354348
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	4/3469	17/18639	0.235294117647059	1.26423956725959	0.392663408542018	0.818913889354348
GO:1990226	histone methyltransferase binding	4/3469	17/18639	0.235294117647059	1.26423956725959	0.392663408542018	0.818913889354348
GO:0005003	ephrin receptor activity	11/3469	53/18639	0.207547169811321	1.11515471262992	0.397608437501577	0.822828572051875
GO:0005005	transmembrane-ephrin receptor activity	11/3469	53/18639	0.207547169811321	1.11515471262992	0.397608437501577	0.822828572051875
GO:0016251	RNA polymerase II general transcription initiation factor activity	11/3469	53/18639	0.207547169811321	1.11515471262992	0.397608437501577	0.822828572051875
GO:0038064	collagen receptor activity	11/3469	53/18639	0.207547169811321	1.11515471262992	0.397608437501577	0.822828572051875
GO:0051018	protein kinase A binding	11/3469	53/18639	0.207547169811321	1.11515471262992	0.397608437501577	0.822828572051875
GO:0004540	RNA nuclease activity	24/3469	121/18639	0.198347107438017	1.06572261041718	0.400337580941058	0.827199839818117
GO:0008080	N-acetyltransferase activity	14/3469	69/18639	0.202898550724638	1.09017759785429	0.407229930737503	0.840146672490757
GO:0004879	nuclear receptor activity	12/3469	59/18639	0.203389830508475	1.0928172530549	0.417725435276282	0.860475896629023
GO:0003925	G protein activity	11/3469	54/18639	0.203703703703704	1.09450369943307	0.42345646339769	0.869007834578524
GO:0003725	double-stranded RNA binding	15/3469	75/18639	0.2	1.07460363217065	0.424273540248569	0.869007834578524
GO:0045499	chemorepellent activity	6/3469	28/18639	0.214285714285714	1.15136103446856	0.424459456859756	0.869007834578524
GO:0051959	dynein light intermediate chain binding	6/3469	28/18639	0.214285714285714	1.15136103446856	0.424459456859756	0.869007834578524
GO:0072341	modified amino acid binding	18/3469	91/18639	0.197802197802198	1.0627948010479	0.428790443705544	0.875699469361089
GO:0035254	glutamate receptor binding	10/3469	49/18639	0.204081632653061	1.09653431854148	0.429587101896232	0.875699469361089
GO:0005125	cytokine activity	45/3469	234/18639	0.192307692307692	1.03327272324101	0.429686987948991	0.875699469361089
GO:0000295	adenine nucleotide transmembrane transporter activity	5/3469	23/18639	0.217391304347826	1.16804742627245	0.431075090899385	0.875866207418295
GO:0003887	DNA-directed DNA polymerase activity	5/3469	23/18639	0.217391304347826	1.16804742627245	0.431075090899385	0.875866207418295
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	4/3469	18/18639	0.222222222222222	1.19400403574517	0.438343396277066	0.882610351963281
GO:0008409	5'-3' exonuclease activity	4/3469	18/18639	0.222222222222222	1.19400403574517	0.438343396277066	0.882610351963281
GO:0017075	syntaxin-1 binding	4/3469	18/18639	0.222222222222222	1.19400403574517	0.438343396277066	0.882610351963281
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	4/3469	18/18639	0.222222222222222	1.19400403574517	0.438343396277066	0.882610351963281
GO:0098641	cadherin binding involved in cell-cell adhesion	4/3469	18/18639	0.222222222222222	1.19400403574517	0.438343396277066	0.882610351963281
GO:1901611	phosphatidylglycerol binding	4/3469	18/18639	0.222222222222222	1.19400403574517	0.438343396277066	0.882610351963281
GO:0005338	nucleotide-sugar transmembrane transporter activity	3/3469	13/18639	0.230769230769231	1.23992726788922	0.446419621417226	0.890846298095982
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	3/3469	13/18639	0.230769230769231	1.23992726788922	0.446419621417226	0.890846298095982
GO:0070123	transforming growth factor beta receptor activity, type III	3/3469	13/18639	0.230769230769231	1.23992726788922	0.446419621417226	0.890846298095982
GO:0071837	HMG box domain binding	3/3469	13/18639	0.230769230769231	1.23992726788922	0.446419621417226	0.890846298095982
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	3/3469	13/18639	0.230769230769231	1.23992726788922	0.446419621417226	0.890846298095982
GO:0089720	caspase binding	3/3469	13/18639	0.230769230769231	1.23992726788922	0.446419621417226	0.890846298095982
GO:0052689	carboxylic ester hydrolase activity	18/3469	92/18639	0.195652173913043	1.05124268364521	0.44870387503698	0.894074140303996
GO:0004518	nuclease activity	40/3469	209/18639	0.191387559808612	1.02832883461307	0.450007281049808	0.895340895975953
GO:0008235	metalloexopeptidase activity	13/3469	66/18639	0.196969696969697	1.05832175895595	0.459566050319283	0.913004553300976
GO:0042605	peptide antigen binding	9/3469	45/18639	0.2	1.07460363217065	0.464865209676394	0.922166044639118
GO:0035035	histone acetyltransferase binding	5/3469	24/18639	0.208333333333333	1.1193787835111	0.470618777164902	0.932200561562974
GO:0008237	metallopeptidase activity	35/3469	184/18639	0.190217391304348	1.02204149798839	0.472883478959726	0.935304934048661
GO:0050997	quaternary ammonium group binding	8/3469	40/18639	0.2	1.07460363217065	0.473863064976807	0.93586210623549
GO:0030170	pyridoxal phosphate binding	11/3469	56/18639	0.196428571428571	1.05541428159618	0.474962450477833	0.936653891309963
GO:0030506	ankyrin binding	4/3469	19/18639	0.210526315789474	1.13116171807437	0.482959210300741	0.944691155725342
GO:0043395	heparan sulfate proteoglycan binding	4/3469	19/18639	0.210526315789474	1.13116171807437	0.482959210300741	0.944691155725342
GO:0046624	sphingolipid transporter activity	4/3469	19/18639	0.210526315789474	1.13116171807437	0.482959210300741	0.944691155725342
GO:1990380	K48-linked deubiquitinase activity	4/3469	19/18639	0.210526315789474	1.13116171807437	0.482959210300741	0.944691155725342
GO:0042054	histone methyltransferase activity	13/3469	67/18639	0.194029850746269	1.04252591180735	0.483038997627756	0.944691155725342
GO:0004623	phospholipase A2 activity	7/3469	35/18639	0.2	1.07460363217065	0.483969294543856	0.944691155725342
GO:0034061	DNA polymerase activity	7/3469	35/18639	0.2	1.07460363217065	0.483969294543856	0.944691155725342
GO:0030276	clathrin binding	9/3469	46/18639	0.195652173913043	1.05124268364521	0.493241956578256	0.952521665787031
GO:0031210	phosphatidylcholine binding	6/3469	30/18639	0.2	1.07460363217065	0.495559765766602	0.952521665787031
GO:0031624	ubiquitin conjugating enzyme binding	6/3469	30/18639	0.2	1.07460363217065	0.495559765766602	0.952521665787031
GO:0048019	receptor antagonist activity	6/3469	30/18639	0.2	1.07460363217065	0.495559765766602	0.952521665787031
GO:0051721	protein phosphatase 2A binding	6/3469	30/18639	0.2	1.07460363217065	0.495559765766602	0.952521665787031
GO:0003727	single-stranded RNA binding	17/3469	89/18639	0.191011235955056	1.02630683971355	0.495606239847971	0.952521665787031
GO:0005545	1-phosphatidylinositol binding	3/3469	14/18639	0.214285714285714	1.15136103446856	0.498635502895225	0.952521665787031
GO:0008559	ABC-type xenobiotic transporter activity	3/3469	14/18639	0.214285714285714	1.15136103446856	0.498635502895225	0.952521665787031
GO:0019992	diacylglycerol binding	3/3469	14/18639	0.214285714285714	1.15136103446856	0.498635502895225	0.952521665787031
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	3/3469	14/18639	0.214285714285714	1.15136103446856	0.498635502895225	0.952521665787031
GO:0042813	Wnt receptor activity	3/3469	14/18639	0.214285714285714	1.15136103446856	0.498635502895225	0.952521665787031
GO:0070742	C2H2 zinc finger domain binding	3/3469	14/18639	0.214285714285714	1.15136103446856	0.498635502895225	0.952521665787031
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	3/3469	14/18639	0.214285714285714	1.15136103446856	0.498635502895225	0.952521665787031
GO:0098821	BMP receptor activity	3/3469	14/18639	0.214285714285714	1.15136103446856	0.498635502895225	0.952521665787031
GO:1901612	cardiolipin binding	3/3469	14/18639	0.214285714285714	1.15136103446856	0.498635502895225	0.952521665787031
GO:0070279	vitamin B6 binding	11/3469	57/18639	0.192982456140351	1.03689824156818	0.500413373163	0.95381147117236
GO:0043130	ubiquitin binding	19/3469	100/18639	0.19	1.02087345056212	0.500733240645296	0.95381147117236
GO:0140223	general transcription initiation factor activity	13/3469	68/18639	0.191176470588235	1.02719464839842	0.506312296427021	0.963070623416504
GO:0015662	P-type ion transporter activity	5/3469	25/18639	0.2	1.07460363217065	0.509240945777881	0.963176457388066
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	5/3469	25/18639	0.2	1.07460363217065	0.509240945777881	0.963176457388066
GO:0047617	fatty acyl-CoA hydrolase activity	5/3469	25/18639	0.2	1.07460363217065	0.509240945777881	0.963176457388066
GO:0140358	P-type transmembrane transporter activity	5/3469	25/18639	0.2	1.07460363217065	0.509240945777881	0.963176457388066
GO:0004033	aldo-keto reductase (NADPH) activity	7/3469	36/18639	0.194444444444444	1.04475353127703	0.516001492550984	0.971851125717513
GO:0004869	cysteine-type endopeptidase inhibitor activity	7/3469	36/18639	0.194444444444444	1.04475353127703	0.516001492550984	0.971851125717513
GO:0045505	dynein intermediate chain binding	7/3469	36/18639	0.194444444444444	1.04475353127703	0.516001492550984	0.971851125717513
GO:0001614	purinergic nucleotide receptor activity	4/3469	20/18639	0.2	1.07460363217065	0.526081191265588	0.985300108222281
GO:0016502	nucleotide receptor activity	4/3469	20/18639	0.2	1.07460363217065	0.526081191265588	0.985300108222281
GO:0031418	L-ascorbic acid binding	4/3469	20/18639	0.2	1.07460363217065	0.526081191265588	0.985300108222281
GO:0140939	histone H4 methyltransferase activity	4/3469	20/18639	0.2	1.07460363217065	0.526081191265588	0.985300108222281
GO:0000049	tRNA binding	15/3469	80/18639	0.1875	1.00744090515999	0.532698283024901	0.994851429173246
GO:0004402	histone acetyltransferase activity	8/3469	42/18639	0.19047619047619	1.02343203063872	0.53340654554479	0.994851429173246
GO:0043175	RNA polymerase core enzyme binding	8/3469	42/18639	0.19047619047619	1.02343203063872	0.53340654554479	0.994851429173246
GO:0035591	signaling adaptor activity	24/3469	129/18639	0.186046511627907	0.999631285740144	0.536700817987612	0.998858173040483
GO:0004435	phosphatidylinositol phospholipase C activity	5/3469	26/18639	0.192307692307692	1.03327272324101	0.546663229983231	0.998858173040483
GO:0004529	DNA exonuclease activity	5/3469	26/18639	0.192307692307692	1.03327272324101	0.546663229983231	0.998858173040483
GO:0016289	acyl-CoA hydrolase activity	5/3469	26/18639	0.192307692307692	1.03327272324101	0.546663229983231	0.998858173040483
GO:0030247	polysaccharide binding	5/3469	26/18639	0.192307692307692	1.03327272324101	0.546663229983231	0.998858173040483
GO:0043548	phosphatidylinositol 3-kinase binding	5/3469	26/18639	0.192307692307692	1.03327272324101	0.546663229983231	0.998858173040483
GO:0030551	cyclic nucleotide binding	7/3469	37/18639	0.189189189189189	1.01651694935062	0.547286737513147	0.998858173040483
GO:0000774	adenyl-nucleotide exchange factor activity	3/3469	15/18639	0.2	1.07460363217065	0.548217461116924	0.998858173040483
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	3/3469	15/18639	0.2	1.07460363217065	0.548217461116924	0.998858173040483
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	3/3469	15/18639	0.2	1.07460363217065	0.548217461116924	0.998858173040483
GO:0015116	sulfate transmembrane transporter activity	3/3469	15/18639	0.2	1.07460363217065	0.548217461116924	0.998858173040483
GO:0015556	C4-dicarboxylate transmembrane transporter activity	3/3469	15/18639	0.2	1.07460363217065	0.548217461116924	0.998858173040483
GO:0015929	hexosaminidase activity	3/3469	15/18639	0.2	1.07460363217065	0.548217461116924	0.998858173040483
GO:0017081	chloride channel regulator activity	3/3469	15/18639	0.2	1.07460363217065	0.548217461116924	0.998858173040483
GO:0033130	acetylcholine receptor binding	3/3469	15/18639	0.2	1.07460363217065	0.548217461116924	0.998858173040483
GO:0034483	heparan sulfate sulfotransferase activity	3/3469	15/18639	0.2	1.07460363217065	0.548217461116924	0.998858173040483
GO:0140776	protein-containing complex destabilizing activity	3/3469	15/18639	0.2	1.07460363217065	0.548217461116924	0.998858173040483
GO:0031593	polyubiquitin modification-dependent protein binding	11/3469	59/18639	0.186440677966102	1.00174914863366	0.550241855021928	1
GO:0016782	transferase activity, transferring sulphur-containing groups	13/3469	70/18639	0.185714285714286	0.997846229872751	0.551975309763847	1
GO:0097110	scaffold protein binding	13/3469	70/18639	0.185714285714286	0.997846229872751	0.551975309763847	1
GO:0004712	protein serine/threonine/tyrosine kinase activity	8/3469	43/18639	0.186046511627907	0.999631285740144	0.562211949185844	1
GO:1901981	phosphatidylinositol phosphate binding	34/3469	185/18639	0.183783783783784	0.987473607940601	0.56266188130354	1
GO:0008373	sialyltransferase activity	4/3469	21/18639	0.19047619047619	1.02343203063872	0.567371745161595	1
GO:0019200	carbohydrate kinase activity	4/3469	21/18639	0.19047619047619	1.02343203063872	0.567371745161595	1
GO:1904047	S-adenosyl-L-methionine binding	4/3469	21/18639	0.19047619047619	1.02343203063872	0.567371745161595	1
GO:0032182	ubiquitin-like protein binding	22/3469	120/18639	0.183333333333333	0.985053329489766	0.568452712873359	1
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	42/3469	229/18639	0.183406113537118	0.985444378846452	0.56923488130119	1
GO:0140299	molecular sensor activity	13/3469	71/18639	0.183098591549296	0.983792057621022	0.574235335101167	1
GO:0060590	ATPase regulator activity	9/3469	49/18639	0.183673469387755	0.986880886687336	0.575406591686462	1
GO:0000182	rDNA binding	2/3469	10/18639	0.2	1.07460363217065	0.580882406687903	1
GO:0003680	minor groove of adenine-thymine-rich DNA binding	2/3469	10/18639	0.2	1.07460363217065	0.580882406687903	1
GO:0004090	carbonyl reductase (NADPH) activity	2/3469	10/18639	0.2	1.07460363217065	0.580882406687903	1
GO:0004445	inositol-polyphosphate 5-phosphatase activity	2/3469	10/18639	0.2	1.07460363217065	0.580882406687903	1
GO:0004862	cAMP-dependent protein kinase inhibitor activity	2/3469	10/18639	0.2	1.07460363217065	0.580882406687903	1
GO:0004935	adrenergic receptor activity	2/3469	10/18639	0.2	1.07460363217065	0.580882406687903	1
GO:0004955	prostaglandin receptor activity	2/3469	10/18639	0.2	1.07460363217065	0.580882406687903	1
GO:0005131	growth hormone receptor binding	2/3469	10/18639	0.2	1.07460363217065	0.580882406687903	1
GO:0005522	profilin binding	2/3469	10/18639	0.2	1.07460363217065	0.580882406687903	1
GO:0008140	cAMP response element binding protein binding	2/3469	10/18639	0.2	1.07460363217065	0.580882406687903	1
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	2/3469	10/18639	0.2	1.07460363217065	0.580882406687903	1
GO:0008519	ammonium channel activity	2/3469	10/18639	0.2	1.07460363217065	0.580882406687903	1
GO:0008641	ubiquitin-like modifier activating enzyme activity	2/3469	10/18639	0.2	1.07460363217065	0.580882406687903	1
GO:0015203	polyamine transmembrane transporter activity	2/3469	10/18639	0.2	1.07460363217065	0.580882406687903	1
GO:0019911	structural constituent of myelin sheath	2/3469	10/18639	0.2	1.07460363217065	0.580882406687903	1
GO:0030957	Tat protein binding	2/3469	10/18639	0.2	1.07460363217065	0.580882406687903	1
GO:0031434	mitogen-activated protein kinase kinase binding	2/3469	10/18639	0.2	1.07460363217065	0.580882406687903	1
GO:0032356	oxidized DNA binding	2/3469	10/18639	0.2	1.07460363217065	0.580882406687903	1
GO:0035256	G protein-coupled glutamate receptor binding	2/3469	10/18639	0.2	1.07460363217065	0.580882406687903	1
GO:0035374	chondroitin sulfate binding	2/3469	10/18639	0.2	1.07460363217065	0.580882406687903	1
GO:0042975	peroxisome proliferator activated receptor binding	2/3469	10/18639	0.2	1.07460363217065	0.580882406687903	1
GO:0043121	neurotrophin binding	2/3469	10/18639	0.2	1.07460363217065	0.580882406687903	1
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	2/3469	10/18639	0.2	1.07460363217065	0.580882406687903	1
GO:0070097	delta-catenin binding	2/3469	10/18639	0.2	1.07460363217065	0.580882406687903	1
GO:1990757	ubiquitin ligase activator activity	2/3469	10/18639	0.2	1.07460363217065	0.580882406687903	1
GO:0001671	ATPase activator activity	5/3469	27/18639	0.185185185185185	0.995003363120976	0.582658757960007	1
GO:0005104	fibroblast growth factor receptor binding	5/3469	27/18639	0.185185185185185	0.995003363120976	0.582658757960007	1
GO:0001046	core promoter sequence-specific DNA binding	8/3469	44/18639	0.181818181818182	0.976912392882413	0.590214836181578	1
GO:0016410	N-acyltransferase activity	17/3469	94/18639	0.180851063829787	0.971716050367081	0.59409023771373	1
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	3/3469	16/18639	0.1875	1.00744090515999	0.594780414794841	1
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	3/3469	16/18639	0.1875	1.00744090515999	0.594780414794841	1
GO:0005324	long-chain fatty acid transmembrane transporter activity	3/3469	16/18639	0.1875	1.00744090515999	0.594780414794841	1
GO:0008296	3'-5'-DNA exonuclease activity	3/3469	16/18639	0.1875	1.00744090515999	0.594780414794841	1
GO:0019841	retinol binding	3/3469	16/18639	0.1875	1.00744090515999	0.594780414794841	1
GO:0030275	LRR domain binding	3/3469	16/18639	0.1875	1.00744090515999	0.594780414794841	1
GO:0034450	ubiquitin-ubiquitin ligase activity	3/3469	16/18639	0.1875	1.00744090515999	0.594780414794841	1
GO:0055102	lipase inhibitor activity	3/3469	16/18639	0.1875	1.00744090515999	0.594780414794841	1
GO:0070411	I-SMAD binding	3/3469	16/18639	0.1875	1.00744090515999	0.594780414794841	1
GO:0097027	ubiquitin-protein transferase activator activity	3/3469	16/18639	0.1875	1.00744090515999	0.594780414794841	1
GO:0140328	floppase activity	3/3469	16/18639	0.1875	1.00744090515999	0.594780414794841	1
GO:0030165	PDZ domain binding	15/3469	83/18639	0.180722891566265	0.971027378467459	0.594790132005999	1
GO:0030296	protein tyrosine kinase activator activity	6/3469	33/18639	0.181818181818182	0.976912392882413	0.595636781747653	1
GO:0042379	chemokine receptor binding	13/3469	72/18639	0.180555555555556	0.970128279042952	0.596036957270278	1
GO:0140035	ubiquitin-like protein reader activity	4/3469	22/18639	0.181818181818182	0.976912392882413	0.60657869848905	1
GO:0000217	DNA secondary structure binding	7/3469	39/18639	0.179487179487179	0.964387875024946	0.607050257182485	1
GO:0050698	proteoglycan sulfotransferase activity	5/3469	28/18639	0.178571428571429	0.959467528723799	0.617049910373105	1
GO:0046915	transition metal ion transmembrane transporter activity	8/3469	45/18639	0.177777777777778	0.955203228596137	0.617317458128645	1
GO:0008376	acetylgalactosaminyltransferase activity	6/3469	34/18639	0.176470588235294	0.948179675444695	0.626553208903939	1
GO:0019825	oxygen binding	6/3469	34/18639	0.176470588235294	0.948179675444695	0.626553208903939	1
GO:0005048	signal sequence binding	9/3469	51/18639	0.176470588235294	0.948179675444695	0.626699276625093	1
GO:1990841	promoter-specific chromatin binding	12/3469	68/18639	0.176470588235294	0.948179675444695	0.629875057139553	1
GO:0003953	NAD+ nucleosidase activity	2/3469	11/18639	0.181818181818182	0.976912392882413	0.635176909802923	1
GO:0004016	adenylate cyclase activity	2/3469	11/18639	0.181818181818182	0.976912392882413	0.635176909802923	1
GO:0004523	RNA-DNA hybrid ribonuclease activity	2/3469	11/18639	0.181818181818182	0.976912392882413	0.635176909802923	1
GO:0004954	prostanoid receptor activity	2/3469	11/18639	0.181818181818182	0.976912392882413	0.635176909802923	1
GO:0005114	type II transforming growth factor beta receptor binding	2/3469	11/18639	0.181818181818182	0.976912392882413	0.635176909802923	1
GO:0005536	D-glucose binding	2/3469	11/18639	0.181818181818182	0.976912392882413	0.635176909802923	1
GO:0008172	S-methyltransferase activity	2/3469	11/18639	0.181818181818182	0.976912392882413	0.635176909802923	1
GO:0008503	benzodiazepine receptor activity	2/3469	11/18639	0.181818181818182	0.976912392882413	0.635176909802923	1
GO:0008526	phosphatidylinositol transfer activity	2/3469	11/18639	0.181818181818182	0.976912392882413	0.635176909802923	1
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	2/3469	11/18639	0.181818181818182	0.976912392882413	0.635176909802923	1
GO:0019215	intermediate filament binding	2/3469	11/18639	0.181818181818182	0.976912392882413	0.635176909802923	1
GO:0032050	clathrin heavy chain binding	2/3469	11/18639	0.181818181818182	0.976912392882413	0.635176909802923	1
GO:0032404	mismatch repair complex binding	2/3469	11/18639	0.181818181818182	0.976912392882413	0.635176909802923	1
GO:0034056	estrogen response element binding	2/3469	11/18639	0.181818181818182	0.976912392882413	0.635176909802923	1
GO:0034511	U3 snoRNA binding	2/3469	11/18639	0.181818181818182	0.976912392882413	0.635176909802923	1
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	2/3469	11/18639	0.181818181818182	0.976912392882413	0.635176909802923	1
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	2/3469	11/18639	0.181818181818182	0.976912392882413	0.635176909802923	1
GO:0050998	nitric-oxide synthase binding	2/3469	11/18639	0.181818181818182	0.976912392882413	0.635176909802923	1
GO:0070697	activin receptor binding	2/3469	11/18639	0.181818181818182	0.976912392882413	0.635176909802923	1
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	2/3469	11/18639	0.181818181818182	0.976912392882413	0.635176909802923	1
GO:0180030	inositol phosphate kinase activity	2/3469	11/18639	0.181818181818182	0.976912392882413	0.635176909802923	1
GO:0061791	GTPase motor activity	7/3469	40/18639	0.175	0.940278178149323	0.635302085832173	1
GO:1990606	membrane scission GTPase motor activity	7/3469	40/18639	0.175	0.940278178149323	0.635302085832173	1
GO:0005516	calmodulin binding	37/3469	207/18639	0.178743961352657	0.960394550490681	0.63592204877683	1
GO:0036041	long-chain fatty acid binding	3/3469	17/18639	0.176470588235294	0.948179675444695	0.638091201849017	1
GO:0038191	neuropilin binding	3/3469	17/18639	0.176470588235294	0.948179675444695	0.638091201849017	1
GO:0045125	bioactive lipid receptor activity	3/3469	17/18639	0.176470588235294	0.948179675444695	0.638091201849017	1
GO:0046965	nuclear retinoid X receptor binding	3/3469	17/18639	0.176470588235294	0.948179675444695	0.638091201849017	1
GO:0070492	oligosaccharide binding	3/3469	17/18639	0.176470588235294	0.948179675444695	0.638091201849017	1
GO:0004175	endopeptidase activity	73/3469	405/18639	0.180246913580247	0.968469940104417	0.640596218160148	1
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	16/3469	91/18639	0.175824175824176	0.944706489820356	0.641816812262788	1
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	4/3469	23/18639	0.173913043478261	0.93443794101796	0.643526826402664	1
GO:0070577	lysine-acetylated histone binding	4/3469	23/18639	0.173913043478261	0.93443794101796	0.643526826402664	1
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	4/3469	23/18639	0.173913043478261	0.93443794101796	0.643526826402664	1
GO:0004181	metallocarboxypeptidase activity	5/3469	29/18639	0.172413793103448	0.926382441526426	0.649704966515605	1
GO:0004629	phospholipase C activity	5/3469	29/18639	0.172413793103448	0.926382441526426	0.649704966515605	1
GO:0043236	laminin binding	5/3469	29/18639	0.172413793103448	0.926382441526426	0.649704966515605	1
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	5/3469	29/18639	0.172413793103448	0.926382441526426	0.649704966515605	1
GO:0002039	p53 binding	12/3469	69/18639	0.173913043478261	0.93443794101796	0.651045898665635	1
GO:0030159	signaling receptor complex adaptor activity	9/3469	52/18639	0.173076923076923	0.929945450916912	0.651063874460234	1
GO:0005154	epidermal growth factor receptor binding	6/3469	35/18639	0.171428571428571	0.921088827574847	0.656053329116369	1
GO:0010485	histone H4 acetyltransferase activity	6/3469	35/18639	0.171428571428571	0.921088827574847	0.656053329116369	1
GO:0140566	histone reader activity	6/3469	35/18639	0.171428571428571	0.921088827574847	0.656053329116369	1
GO:0004620	phospholipase activity	19/3469	109/18639	0.174311926605505	0.936581147304699	0.662673493309361	1
GO:0005506	iron ion binding	27/3469	154/18639	0.175324675324675	0.942022664565184	0.667109288643724	1
GO:0008146	sulfotransferase activity	9/3469	53/18639	0.169811320754717	0.912399310333574	0.674498252001126	1
GO:0140597	protein carrier chaperone	33/3469	188/18639	0.175531914893617	0.943136166532755	0.674909624638442	1
GO:0140098	catalytic activity, acting on RNA	69/3469	387/18639	0.178294573643411	0.957979982167638	0.675424257379124	1
GO:0051213	dioxygenase activity	16/3469	93/18639	0.172043010752688	0.924390221222068	0.677647431614065	1
GO:0017022	myosin binding	13/3469	76/18639	0.171052631578947	0.919068895935428	0.677727017241552	1
GO:0000400	four-way junction DNA binding	3/3469	18/18639	0.166666666666667	0.895503026808879	0.678040762963408	1
GO:0015172	acidic amino acid transmembrane transporter activity	3/3469	18/18639	0.166666666666667	0.895503026808879	0.678040762963408	1
GO:0017128	phospholipid scramblase activity	3/3469	18/18639	0.166666666666667	0.895503026808879	0.678040762963408	1
GO:0034185	apolipoprotein binding	3/3469	18/18639	0.166666666666667	0.895503026808879	0.678040762963408	1
GO:0050811	GABA receptor binding	3/3469	18/18639	0.166666666666667	0.895503026808879	0.678040762963408	1
GO:0005315	phosphate transmembrane transporter activity	4/3469	24/18639	0.166666666666667	0.895503026808879	0.678108436250217	1
GO:0030215	semaphorin receptor binding	4/3469	24/18639	0.166666666666667	0.895503026808879	0.678108436250217	1
GO:0030552	cAMP binding	4/3469	24/18639	0.166666666666667	0.895503026808879	0.678108436250217	1
GO:0050699	WW domain binding	4/3469	24/18639	0.166666666666667	0.895503026808879	0.678108436250217	1
GO:0070300	phosphatidic acid binding	4/3469	24/18639	0.166666666666667	0.895503026808879	0.678108436250217	1
GO:0070840	dynein complex binding	4/3469	24/18639	0.166666666666667	0.895503026808879	0.678108436250217	1
GO:0140033	acetylation-dependent protein binding	4/3469	24/18639	0.166666666666667	0.895503026808879	0.678108436250217	1
GO:0004222	metalloendopeptidase activity	19/3469	110/18639	0.172727272727273	0.928066773238292	0.678904122882191	1
GO:0015459	potassium channel regulator activity	10/3469	59/18639	0.169491525423729	0.910681044212419	0.680296231321143	1
GO:0036002	pre-mRNA binding	10/3469	59/18639	0.169491525423729	0.910681044212419	0.680296231321143	1
GO:0043995	histone H4K5 acetyltransferase activity	5/3469	30/18639	0.166666666666667	0.895503026808879	0.680534006665405	1
GO:0043996	histone H4K8 acetyltransferase activity	5/3469	30/18639	0.166666666666667	0.895503026808879	0.680534006665405	1
GO:0043997	histone H4K12 acetyltransferase activity	5/3469	30/18639	0.166666666666667	0.895503026808879	0.680534006665405	1
GO:0003720	telomerase activity	2/3469	12/18639	0.166666666666667	0.895503026808879	0.683785180035878	1
GO:0003995	acyl-CoA dehydrogenase activity	2/3469	12/18639	0.166666666666667	0.895503026808879	0.683785180035878	1
GO:0004000	adenosine deaminase activity	2/3469	12/18639	0.166666666666667	0.895503026808879	0.683785180035878	1
GO:0005049	nuclear export signal receptor activity	2/3469	12/18639	0.166666666666667	0.895503026808879	0.683785180035878	1
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	2/3469	12/18639	0.166666666666667	0.895503026808879	0.683785180035878	1
GO:0015132	prostaglandin transmembrane transporter activity	2/3469	12/18639	0.166666666666667	0.895503026808879	0.683785180035878	1
GO:0035014	phosphatidylinositol 3-kinase regulator activity	2/3469	12/18639	0.166666666666667	0.895503026808879	0.683785180035878	1
GO:0042301	phosphate ion binding	2/3469	12/18639	0.166666666666667	0.895503026808879	0.683785180035878	1
GO:0045295	gamma-catenin binding	2/3469	12/18639	0.166666666666667	0.895503026808879	0.683785180035878	1
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	2/3469	12/18639	0.166666666666667	0.895503026808879	0.683785180035878	1
GO:0070410	co-SMAD binding	2/3469	12/18639	0.166666666666667	0.895503026808879	0.683785180035878	1
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	2/3469	12/18639	0.166666666666667	0.895503026808879	0.683785180035878	1
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	2/3469	12/18639	0.166666666666667	0.895503026808879	0.683785180035878	1
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	2/3469	12/18639	0.166666666666667	0.895503026808879	0.683785180035878	1
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	2/3469	12/18639	0.166666666666667	0.895503026808879	0.683785180035878	1
GO:1990459	transferrin receptor binding	2/3469	12/18639	0.166666666666667	0.895503026808879	0.683785180035878	1
GO:0000993	RNA polymerase II complex binding	6/3469	36/18639	0.166666666666667	0.895503026808879	0.684063696429446	1
GO:0019894	kinesin binding	7/3469	42/18639	0.166666666666667	0.895503026808879	0.688141985034299	1
GO:0016887	ATP hydrolysis activity	74/3469	417/18639	0.177458033573141	0.953485237177799	0.696250636813259	1
GO:0015631	tubulin binding	68/3469	385/18639	0.176623376623377	0.94900061022863	0.705506895509058	1
GO:0005310	dicarboxylic acid transmembrane transporter activity	5/3469	31/18639	0.161290322580645	0.866615832395689	0.709484378884105	1
GO:0072349	modified amino acid transmembrane transporter activity	5/3469	31/18639	0.161290322580645	0.866615832395689	0.709484378884105	1
GO:0005537	D-mannose binding	4/3469	25/18639	0.16	0.859682905736524	0.710273672530662	1
GO:0008139	nuclear localization sequence binding	4/3469	25/18639	0.16	0.859682905736524	0.710273672530662	1
GO:0042974	nuclear retinoic acid receptor binding	4/3469	25/18639	0.16	0.859682905736524	0.710273672530662	1
GO:0022829	wide pore channel activity	6/3469	37/18639	0.162162162162162	0.871300242300531	0.710536656219698	1
GO:0008375	acetylglucosaminyltransferase activity	7/3469	43/18639	0.162790697674419	0.874677375022626	0.71262838089372	1
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	3/3469	19/18639	0.157894736842105	0.84837128855578	0.714618554087658	1
GO:0008381	mechanosensitive monoatomic ion channel activity	3/3469	19/18639	0.157894736842105	0.84837128855578	0.714618554087658	1
GO:0008574	plus-end-directed microtubule motor activity	3/3469	19/18639	0.157894736842105	0.84837128855578	0.714618554087658	1
GO:0015245	fatty acid transmembrane transporter activity	3/3469	19/18639	0.157894736842105	0.84837128855578	0.714618554087658	1
GO:0016918	retinal binding	3/3469	19/18639	0.157894736842105	0.84837128855578	0.714618554087658	1
GO:0042834	peptidoglycan binding	3/3469	19/18639	0.157894736842105	0.84837128855578	0.714618554087658	1
GO:0140036	ubiquitin-modified protein reader activity	3/3469	19/18639	0.157894736842105	0.84837128855578	0.714618554087658	1
GO:0004527	exonuclease activity	14/3469	84/18639	0.166666666666667	0.895503026808879	0.719071419714644	1
GO:0019905	syntaxin binding	10/3469	61/18639	0.163934426229508	0.880822649320208	0.721732221530538	1
GO:0003964	RNA-directed DNA polymerase activity	2/3469	13/18639	0.153846153846154	0.826618178592811	0.726942554330179	1
GO:0004535	poly(A)-specific ribonuclease activity	2/3469	13/18639	0.153846153846154	0.826618178592811	0.726942554330179	1
GO:0008035	high-density lipoprotein particle binding	2/3469	13/18639	0.153846153846154	0.826618178592811	0.726942554330179	1
GO:0009982	pseudouridine synthase activity	2/3469	13/18639	0.153846153846154	0.826618178592811	0.726942554330179	1
GO:0045159	myosin II binding	2/3469	13/18639	0.153846153846154	0.826618178592811	0.726942554330179	1
GO:0071714	icosanoid transmembrane transporter activity	2/3469	13/18639	0.153846153846154	0.826618178592811	0.726942554330179	1
GO:0140333	glycerophospholipid flippase activity	2/3469	13/18639	0.153846153846154	0.826618178592811	0.726942554330179	1
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	2/3469	13/18639	0.153846153846154	0.826618178592811	0.726942554330179	1
GO:0033293	monocarboxylic acid binding	13/3469	79/18639	0.164556962025316	0.884167545456867	0.732258504419447	1
GO:0005501	retinoid binding	6/3469	38/18639	0.157894736842105	0.84837128855578	0.735447692525926	1
GO:0019840	isoprenoid binding	6/3469	38/18639	0.157894736842105	0.84837128855578	0.735447692525926	1
GO:0001223	transcription coactivator binding	7/3469	44/18639	0.159090909090909	0.854798343772111	0.735787700163585	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	5/3469	32/18639	0.15625	0.839534087633324	0.736535980631021	1
GO:0042910	xenobiotic transmembrane transporter activity	5/3469	32/18639	0.15625	0.839534087633324	0.736535980631021	1
GO:0005548	phospholipid transporter activity	11/3469	68/18639	0.161764705882353	0.86916470249097	0.743571904444609	1
GO:0015095	magnesium ion transmembrane transporter activity	3/3469	20/18639	0.15	0.805952724127991	0.747889853409199	1
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	3/3469	20/18639	0.15	0.805952724127991	0.747889853409199	1
GO:0005319	lipid transporter activity	30/3469	178/18639	0.168539325842697	0.905564858570776	0.755493596865599	1
GO:0140303	intramembrane lipid transporter activity	7/3469	45/18639	0.155555555555556	0.83580282502162	0.757611165801601	1
GO:1901682	sulfur compound transmembrane transporter activity	10/3469	63/18639	0.158730158730159	0.852860025532265	0.759500706046661	1
GO:0071889	14-3-3 protein binding	5/3469	33/18639	0.151515151515152	0.814093660735344	0.761696551860195	1
GO:0004705	JUN kinase activity	2/3469	14/18639	0.142857142857143	0.767574022979039	0.764993729569338	1
GO:0005313	L-glutamate transmembrane transporter activity	2/3469	14/18639	0.142857142857143	0.767574022979039	0.764993729569338	1
GO:0008174	mRNA methyltransferase activity	2/3469	14/18639	0.142857142857143	0.767574022979039	0.764993729569338	1
GO:0008191	metalloendopeptidase inhibitor activity	2/3469	14/18639	0.142857142857143	0.767574022979039	0.764993729569338	1
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	2/3469	14/18639	0.142857142857143	0.767574022979039	0.764993729569338	1
GO:0030983	mismatched DNA binding	2/3469	14/18639	0.142857142857143	0.767574022979039	0.764993729569338	1
GO:0044548	S100 protein binding	2/3469	14/18639	0.142857142857143	0.767574022979039	0.764993729569338	1
GO:0046030	inositol trisphosphate phosphatase activity	2/3469	14/18639	0.142857142857143	0.767574022979039	0.764993729569338	1
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	2/3469	14/18639	0.142857142857143	0.767574022979039	0.764993729569338	1
GO:1901474	azole transmembrane transporter activity	2/3469	14/18639	0.142857142857143	0.767574022979039	0.764993729569338	1
GO:1990825	sequence-specific mRNA binding	2/3469	14/18639	0.142857142857143	0.767574022979039	0.764993729569338	1
GO:0008266	poly(U) RNA binding	4/3469	27/18639	0.148148148148148	0.796002690496781	0.767388376636077	1
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	4/3469	27/18639	0.148148148148148	0.796002690496781	0.767388376636077	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	8/3469	52/18639	0.153846153846154	0.826618178592811	0.776916164362738	1
GO:0004536	DNA nuclease activity	10/3469	64/18639	0.15625	0.839534087633324	0.776988928977136	1
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	3/3469	21/18639	0.142857142857143	0.767574022979039	0.7779762047838	1
GO:0051010	microtubule plus-end binding	3/3469	21/18639	0.142857142857143	0.767574022979039	0.7779762047838	1
GO:0061891	calcium ion sensor activity	3/3469	21/18639	0.142857142857143	0.767574022979039	0.7779762047838	1
GO:0030414	peptidase inhibitor activity	28/3469	169/18639	0.165680473372781	0.89020419233072	0.781435350892613	1
GO:0008175	tRNA methyltransferase activity	5/3469	34/18639	0.147058823529412	0.790149729537246	0.784997128231963	1
GO:0090482	vitamin transmembrane transporter activity	5/3469	34/18639	0.147058823529412	0.790149729537246	0.784997128231963	1
GO:0000149	SNARE binding	17/3469	106/18639	0.160377358490566	0.861710459759487	0.787818029133035	1
GO:0036408	histone H3K14 acetyltransferase activity	4/3469	28/18639	0.142857142857143	0.767574022979039	0.792444787679906	1
GO:0001786	phosphatidylserine binding	9/3469	59/18639	0.152542372881356	0.819612939791177	0.793969770281862	1
GO:0070888	E-box binding	9/3469	59/18639	0.152542372881356	0.819612939791177	0.793969770281862	1
GO:0005544	calcium-dependent phospholipid binding	8/3469	53/18639	0.150943396226415	0.8110216091854	0.795123793227024	1
GO:0140359	ABC-type transporter activity	7/3469	47/18639	0.148936170212766	0.800236747361125	0.797282019999604	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	2/3469	15/18639	0.133333333333333	0.716402421447103	0.798343924715863	1
GO:0010181	FMN binding	2/3469	15/18639	0.133333333333333	0.716402421447103	0.798343924715863	1
GO:0030553	cGMP binding	2/3469	15/18639	0.133333333333333	0.716402421447103	0.798343924715863	1
GO:0042809	nuclear vitamin D receptor binding	2/3469	15/18639	0.133333333333333	0.716402421447103	0.798343924715863	1
GO:0047372	monoacylglycerol lipase activity	2/3469	15/18639	0.133333333333333	0.716402421447103	0.798343924715863	1
GO:0048531	beta-1,3-galactosyltransferase activity	2/3469	15/18639	0.133333333333333	0.716402421447103	0.798343924715863	1
GO:0001727	lipid kinase activity	6/3469	41/18639	0.146341463414634	0.786295340612674	0.800853549028606	1
GO:0016877	ligase activity, forming carbon-sulfur bonds	6/3469	41/18639	0.146341463414634	0.786295340612674	0.800853549028606	1
GO:0015377	chloride:monoatomic cation symporter activity	3/3469	22/18639	0.136363636363636	0.73268429466181	0.805038968935602	1
GO:0140784	metal ion sensor activity	3/3469	22/18639	0.136363636363636	0.73268429466181	0.805038968935602	1
GO:0016229	steroid dehydrogenase activity	5/3469	35/18639	0.142857142857143	0.767574022979039	0.806487761417895	1
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	9/3469	60/18639	0.15	0.805952724127991	0.810294191630745	1
GO:0140463	chromatin-protein adaptor activity	8/3469	54/18639	0.148148148148148	0.796002690496781	0.812195654806256	1
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	83/3469	484/18639	0.171487603305785	0.921406006923185	0.814538093755868	1
GO:0005416	amino acid:monoatomic cation symporter activity	4/3469	29/18639	0.137931034482759	0.741105953221141	0.815283159066193	1
GO:0010484	histone H3 acetyltransferase activity	4/3469	29/18639	0.137931034482759	0.741105953221141	0.815283159066193	1
GO:0106222	lncRNA binding	4/3469	29/18639	0.137931034482759	0.741105953221141	0.815283159066193	1
GO:0004866	endopeptidase inhibitor activity	26/3469	161/18639	0.161490683229814	0.867692373802392	0.8171545598723	1
GO:0019787	ubiquitin-like protein transferase activity	82/3469	479/18639	0.171189979123173	0.919806866784902	0.818013495790638	1
GO:0016755	aminoacyltransferase activity	85/3469	496/18639	0.171370967741935	0.920779321920419	0.819064384727687	1
GO:0031492	nucleosomal DNA binding	6/3469	42/18639	0.142857142857143	0.767574022979039	0.819638809694324	1
GO:0035198	miRNA binding	6/3469	42/18639	0.142857142857143	0.767574022979039	0.819638809694324	1
GO:0140030	modification-dependent protein binding	28/3469	173/18639	0.161849710982659	0.86962143643868	0.821026625829586	1
GO:0001216	DNA-binding transcription activator activity	84/3469	491/18639	0.171079429735234	0.919212882915835	0.822452656096504	1
GO:0003688	DNA replication origin binding	2/3469	16/18639	0.125	0.671627270106659	0.827424426133152	1
GO:0004707	MAP kinase activity	2/3469	16/18639	0.125	0.671627270106659	0.827424426133152	1
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	2/3469	16/18639	0.125	0.671627270106659	0.827424426133152	1
GO:0016722	oxidoreductase activity, acting on metal ions	2/3469	16/18639	0.125	0.671627270106659	0.827424426133152	1
GO:0022858	alanine transmembrane transporter activity	2/3469	16/18639	0.125	0.671627270106659	0.827424426133152	1
GO:0031435	mitogen-activated protein kinase kinase kinase binding	2/3469	16/18639	0.125	0.671627270106659	0.827424426133152	1
GO:0140327	flippase activity	2/3469	16/18639	0.125	0.671627270106659	0.827424426133152	1
GO:0019783	ubiquitin-like protein peptidase activity	20/3469	127/18639	0.15748031496063	0.846144592260358	0.827517422431826	1
GO:0005283	amino acid:sodium symporter activity	3/3469	23/18639	0.130434782608696	0.70082845576347	0.829265790315543	1
GO:0099186	structural constituent of postsynapse	3/3469	23/18639	0.130434782608696	0.70082845576347	0.829265790315543	1
GO:0140101	catalytic activity, acting on a tRNA	22/3469	139/18639	0.158273381294964	0.850405752077496	0.830084178028583	1
GO:0046982	protein heterodimerization activity	62/3469	369/18639	0.168021680216802	0.902783539221959	0.833714323087456	1
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	13/3469	86/18639	0.151162790697674	0.812200419663867	0.834730057487634	1
GO:0050660	flavin adenine dinucleotide binding	13/3469	86/18639	0.151162790697674	0.812200419663867	0.834730057487634	1
GO:0001965	G-protein alpha-subunit binding	4/3469	30/18639	0.133333333333333	0.716402421447103	0.836013797897084	1
GO:0008187	poly-pyrimidine tract binding	4/3469	30/18639	0.133333333333333	0.716402421447103	0.836013797897084	1
GO:0070566	adenylyltransferase activity	4/3469	30/18639	0.133333333333333	0.716402421447103	0.836013797897084	1
GO:0005245	voltage-gated calcium channel activity	6/3469	43/18639	0.13953488372093	0.749723464305108	0.83699185220253	1
GO:0048020	CCR chemokine receptor binding	7/3469	50/18639	0.14	0.752222542519458	0.8472425888459	1
GO:0016279	protein-lysine N-methyltransferase activity	10/3469	69/18639	0.144927536231884	0.778698284181634	0.850779575378854	1
GO:0004806	triacylglycerol lipase activity	3/3469	24/18639	0.125	0.671627270106659	0.850859698039161	1
GO:0043998	histone H2A acetyltransferase activity	3/3469	24/18639	0.125	0.671627270106659	0.850859698039161	1
GO:0061659	ubiquitin-like protein ligase activity	62/3469	372/18639	0.166666666666667	0.895503026808879	0.851366227276767	1
GO:0008569	minus-end-directed microtubule motor activity	2/3469	17/18639	0.117647058823529	0.632119783629797	0.852668856037704	1
GO:0031489	myosin V binding	2/3469	17/18639	0.117647058823529	0.632119783629797	0.852668856037704	1
GO:0032183	SUMO binding	2/3469	17/18639	0.117647058823529	0.632119783629797	0.852668856037704	1
GO:0045236	CXCR chemokine receptor binding	2/3469	17/18639	0.117647058823529	0.632119783629797	0.852668856037704	1
GO:0043014	alpha-tubulin binding	6/3469	44/18639	0.136363636363636	0.73268429466181	0.852971455156047	1
GO:0008327	methyl-CpG binding	4/3469	31/18639	0.129032258064516	0.693292665916551	0.854758897010118	1
GO:0016878	acid-thiol ligase activity	4/3469	31/18639	0.129032258064516	0.693292665916551	0.854758897010118	1
GO:0070273	phosphatidylinositol-4-phosphate binding	4/3469	31/18639	0.129032258064516	0.693292665916551	0.854758897010118	1
GO:0016298	lipase activity	20/3469	130/18639	0.153846153846154	0.826618178592811	0.856748180510001	1
GO:0000146	microfilament motor activity	5/3469	38/18639	0.131578947368421	0.706976073796483	0.860805696663201	1
GO:0042162	telomeric DNA binding	5/3469	38/18639	0.131578947368421	0.706976073796483	0.860805696663201	1
GO:0016278	lysine N-methyltransferase activity	10/3469	70/18639	0.142857142857143	0.767574022979039	0.862939391837807	1
GO:0008408	3'-5' exonuclease activity	8/3469	58/18639	0.137931034482759	0.741105953221141	0.869722811098784	1
GO:0061980	regulatory RNA binding	8/3469	58/18639	0.137931034482759	0.741105953221141	0.869722811098784	1
GO:0005251	delayed rectifier potassium channel activity	3/3469	25/18639	0.12	0.644762179302393	0.870030519699411	1
GO:0015296	monoatomic anion:monoatomic cation symporter activity	3/3469	25/18639	0.12	0.644762179302393	0.870030519699411	1
GO:0015645	fatty acid ligase activity	3/3469	25/18639	0.12	0.644762179302393	0.870030519699411	1
GO:0017056	structural constituent of nuclear pore	3/3469	25/18639	0.12	0.644762179302393	0.870030519699411	1
GO:0120515	fatty acid-CoA ligase activity	3/3469	25/18639	0.12	0.644762179302393	0.870030519699411	1
GO:0070717	poly-purine tract binding	4/3469	32/18639	0.125	0.671627270106659	0.871647885064275	1
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	1/3469	10/18639	0.1	0.537301816085327	0.87253531860535	1
GO:0003796	lysozyme activity	1/3469	10/18639	0.1	0.537301816085327	0.87253531860535	1
GO:0004382	GDP phosphatase activity	1/3469	10/18639	0.1	0.537301816085327	0.87253531860535	1
GO:0005337	nucleoside transmembrane transporter activity	1/3469	10/18639	0.1	0.537301816085327	0.87253531860535	1
GO:0015187	glycine transmembrane transporter activity	1/3469	10/18639	0.1	0.537301816085327	0.87253531860535	1
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/3469	10/18639	0.1	0.537301816085327	0.87253531860535	1
GO:0016427	tRNA (cytidine) methyltransferase activity	1/3469	10/18639	0.1	0.537301816085327	0.87253531860535	1
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	1/3469	10/18639	0.1	0.537301816085327	0.87253531860535	1
GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	1/3469	10/18639	0.1	0.537301816085327	0.87253531860535	1
GO:0016868	intramolecular phosphotransferase activity	1/3469	10/18639	0.1	0.537301816085327	0.87253531860535	1
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1/3469	10/18639	0.1	0.537301816085327	0.87253531860535	1
GO:0019531	oxalate transmembrane transporter activity	1/3469	10/18639	0.1	0.537301816085327	0.87253531860535	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/3469	10/18639	0.1	0.537301816085327	0.87253531860535	1
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/3469	10/18639	0.1	0.537301816085327	0.87253531860535	1
GO:0032052	bile acid binding	1/3469	10/18639	0.1	0.537301816085327	0.87253531860535	1
GO:0045322	unmethylated CpG binding	1/3469	10/18639	0.1	0.537301816085327	0.87253531860535	1
GO:0051864	histone H3K36 demethylase activity	1/3469	10/18639	0.1	0.537301816085327	0.87253531860535	1
GO:0070739	protein-glutamic acid ligase activity	1/3469	10/18639	0.1	0.537301816085327	0.87253531860535	1
GO:0070740	tubulin-glutamic acid ligase activity	1/3469	10/18639	0.1	0.537301816085327	0.87253531860535	1
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/3469	10/18639	0.1	0.537301816085327	0.87253531860535	1
GO:0099122	RNA polymerase II C-terminal domain binding	1/3469	10/18639	0.1	0.537301816085327	0.87253531860535	1
GO:0140135	mechanosensitive monoatomic cation channel activity	1/3469	10/18639	0.1	0.537301816085327	0.87253531860535	1
GO:1990763	arrestin family protein binding	1/3469	10/18639	0.1	0.537301816085327	0.87253531860535	1
GO:0004970	glutamate-gated receptor activity	2/3469	18/18639	0.111111111111111	0.597002017872586	0.874497367671991	1
GO:0005372	water transmembrane transporter activity	2/3469	18/18639	0.111111111111111	0.597002017872586	0.874497367671991	1
GO:0008525	phosphatidylcholine transporter activity	2/3469	18/18639	0.111111111111111	0.597002017872586	0.874497367671991	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	2/3469	18/18639	0.111111111111111	0.597002017872586	0.874497367671991	1
GO:0101005	deubiquitinase activity	17/3469	115/18639	0.147826086956522	0.794272249865266	0.883049312752708	1
GO:0005253	monoatomic anion channel activity	15/3469	103/18639	0.145631067961165	0.782478372939797	0.884702498568932	1
GO:0019239	deaminase activity	4/3469	33/18639	0.121212121212121	0.651274928588275	0.886813586195872	1
GO:0001637	G protein-coupled chemoattractant receptor activity	3/3469	26/18639	0.115384615384615	0.619963633944608	0.886988279783538	1
GO:0004950	chemokine receptor activity	3/3469	26/18639	0.115384615384615	0.619963633944608	0.886988279783538	1
GO:0008143	poly(A) binding	3/3469	26/18639	0.115384615384615	0.619963633944608	0.886988279783538	1
GO:0015144	carbohydrate transmembrane transporter activity	5/3469	40/18639	0.125	0.671627270106659	0.889410821060071	1
GO:0071855	neuropeptide receptor binding	5/3469	40/18639	0.125	0.671627270106659	0.889410821060071	1
GO:0042393	histone binding	39/3469	247/18639	0.157894736842105	0.84837128855578	0.892383733017774	1
GO:0005229	intracellularly calcium-gated chloride channel activity	2/3469	19/18639	0.105263157894737	0.565580859037186	0.893306639858383	1
GO:0022821	solute:potassium antiporter activity	2/3469	19/18639	0.105263157894737	0.565580859037186	0.893306639858383	1
GO:0022840	leak channel activity	2/3469	19/18639	0.105263157894737	0.565580859037186	0.893306639858383	1
GO:0022842	narrow pore channel activity	2/3469	19/18639	0.105263157894737	0.565580859037186	0.893306639858383	1
GO:0034987	immunoglobulin receptor binding	2/3469	19/18639	0.105263157894737	0.565580859037186	0.893306639858383	1
GO:0141147	intracellularly calcium-gated channel activity	2/3469	19/18639	0.105263157894737	0.565580859037186	0.893306639858383	1
GO:0003774	cytoskeletal motor activity	23/3469	153/18639	0.150326797385621	0.807708612415851	0.896251541624872	1
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	1/3469	11/18639	0.0909090909090909	0.488456196441207	0.896271159485593	1
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	1/3469	11/18639	0.0909090909090909	0.488456196441207	0.896271159485593	1
GO:0005221	intracellularly cyclic nucleotide-activated monoatomic cation channel activity	1/3469	11/18639	0.0909090909090909	0.488456196441207	0.896271159485593	1
GO:0008199	ferric iron binding	1/3469	11/18639	0.0909090909090909	0.488456196441207	0.896271159485593	1
GO:0015173	aromatic amino acid transmembrane transporter activity	1/3469	11/18639	0.0909090909090909	0.488456196441207	0.896271159485593	1
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/3469	11/18639	0.0909090909090909	0.488456196441207	0.896271159485593	1
GO:0043522	leucine zipper domain binding	1/3469	11/18639	0.0909090909090909	0.488456196441207	0.896271159485593	1
GO:0043855	cyclic nucleotide-activated monoatomic ion channel activity	1/3469	11/18639	0.0909090909090909	0.488456196441207	0.896271159485593	1
GO:0047676	arachidonate-CoA ligase activity	1/3469	11/18639	0.0909090909090909	0.488456196441207	0.896271159485593	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/3469	11/18639	0.0909090909090909	0.488456196441207	0.896271159485593	1
GO:0015297	antiporter activity	20/3469	135/18639	0.148148148148148	0.796002690496781	0.896862103092081	1
GO:1902936	phosphatidylinositol bisphosphate binding	16/3469	111/18639	0.144144144144144	0.774489104267138	0.899748044310709	1
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	4/3469	34/18639	0.117647058823529	0.632119783629797	0.900389113924393	1
GO:0015175	neutral L-amino acid transmembrane transporter activity	5/3469	41/18639	0.121951219512195	0.655246117177228	0.901710442175552	1
GO:0140828	metal cation:monoatomic cation antiporter activity	5/3469	41/18639	0.121951219512195	0.655246117177228	0.901710442175552	1
GO:0004683	calcium/calmodulin-dependent protein kinase activity	3/3469	27/18639	0.111111111111111	0.597002017872586	0.901938267676971	1
GO:0016405	CoA-ligase activity	3/3469	27/18639	0.111111111111111	0.597002017872586	0.901938267676971	1
GO:0031491	nucleosome binding	10/3469	74/18639	0.135135135135135	0.726083535250442	0.903845912870228	1
GO:0035064	methylated histone binding	10/3469	74/18639	0.135135135135135	0.726083535250442	0.903845912870228	1
GO:0003777	microtubule motor activity	9/3469	68/18639	0.132352941176471	0.711134756583521	0.907529460184776	1
GO:0008013	beta-catenin binding	15/3469	106/18639	0.141509433962264	0.760332758611312	0.908401172721276	1
GO:0001972	retinoic acid binding	2/3469	20/18639	0.1	0.537301816085327	0.909464060574959	1
GO:0052745	inositol phosphate phosphatase activity	2/3469	20/18639	0.1	0.537301816085327	0.909464060574959	1
GO:0005262	calcium channel activity	19/3469	131/18639	0.145038167938931	0.779292710352765	0.910827190164473	1
GO:0015179	L-amino acid transmembrane transporter activity	8/3469	62/18639	0.129032258064516	0.693292665916551	0.911972537845463	1
GO:0004520	DNA endonuclease activity	5/3469	42/18639	0.119047619047619	0.639645019149199	0.912801203321664	1
GO:0004842	ubiquitin-protein transferase activity	73/3469	449/18639	0.162583518930958	0.873564199871467	0.914591217416023	1
GO:0016866	intramolecular transferase activity	3/3469	28/18639	0.107142857142857	0.575680517234279	0.915077485276618	1
GO:0004126	cytidine deaminase activity	1/3469	12/18639	0.0833333333333333	0.447751513404439	0.915588066708294	1
GO:0005078	MAP-kinase scaffold activity	1/3469	12/18639	0.0833333333333333	0.447751513404439	0.915588066708294	1
GO:0008504	monoamine transmembrane transporter activity	1/3469	12/18639	0.0833333333333333	0.447751513404439	0.915588066708294	1
GO:0015166	polyol transmembrane transporter activity	1/3469	12/18639	0.0833333333333333	0.447751513404439	0.915588066708294	1
GO:0035197	siRNA binding	1/3469	12/18639	0.0833333333333333	0.447751513404439	0.915588066708294	1
GO:0035251	UDP-glucosyltransferase activity	1/3469	12/18639	0.0833333333333333	0.447751513404439	0.915588066708294	1
GO:0070008	serine-type exopeptidase activity	1/3469	12/18639	0.0833333333333333	0.447751513404439	0.915588066708294	1
GO:0097677	STAT family protein binding	1/3469	12/18639	0.0833333333333333	0.447751513404439	0.915588066708294	1
GO:0140829	bicarbonate:monoatomic anion antiporter activity	1/3469	12/18639	0.0833333333333333	0.447751513404439	0.915588066708294	1
GO:0140900	chloride:bicarbonate antiporter activity	1/3469	12/18639	0.0833333333333333	0.447751513404439	0.915588066708294	1
GO:0140034	methylation-dependent protein binding	10/3469	76/18639	0.131578947368421	0.706976073796483	0.920127165287906	1
GO:0004843	cysteine-type deubiquitinase activity	15/3469	108/18639	0.138888888888889	0.746252522340732	0.921850743542476	1
GO:0061630	ubiquitin protein ligase activity	56/3469	353/18639	0.158640226628895	0.852376818718933	0.922672603256155	1
GO:0005248	voltage-gated sodium channel activity	2/3469	21/18639	0.0952380952380952	0.511716015319359	0.923304887500344	1
GO:0010314	phosphatidylinositol-5-phosphate binding	2/3469	21/18639	0.0952380952380952	0.511716015319359	0.923304887500344	1
GO:0015125	bile acid transmembrane transporter activity	2/3469	21/18639	0.0952380952380952	0.511716015319359	0.923304887500344	1
GO:0036122	BMP binding	2/3469	21/18639	0.0952380952380952	0.511716015319359	0.923304887500344	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	9/3469	70/18639	0.128571428571429	0.690816620681135	0.923876745522233	1
GO:0004896	cytokine receptor activity	13/3469	96/18639	0.135416666666667	0.727596209282214	0.925676035525394	1
GO:0035250	UDP-galactosyltransferase activity	3/3469	29/18639	0.103448275862069	0.555829464915856	0.926592215223975	1
GO:0035173	histone kinase activity	57/3469	360/18639	0.158333333333333	0.850727875468435	0.92678229572167	1
GO:0002161	aminoacyl-tRNA editing activity	1/3469	13/18639	0.0769230769230769	0.413309089296406	0.931308526073137	1
GO:0004465	lipoprotein lipase activity	1/3469	13/18639	0.0769230769230769	0.413309089296406	0.931308526073137	1
GO:0008417	fucosyltransferase activity	1/3469	13/18639	0.0769230769230769	0.413309089296406	0.931308526073137	1
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/3469	13/18639	0.0769230769230769	0.413309089296406	0.931308526073137	1
GO:0030955	potassium ion binding	1/3469	13/18639	0.0769230769230769	0.413309089296406	0.931308526073137	1
GO:0031994	insulin-like growth factor I binding	1/3469	13/18639	0.0769230769230769	0.413309089296406	0.931308526073137	1
GO:0046974	histone H3K9 methyltransferase activity	1/3469	13/18639	0.0769230769230769	0.413309089296406	0.931308526073137	1
GO:0051011	microtubule minus-end binding	1/3469	13/18639	0.0769230769230769	0.413309089296406	0.931308526073137	1
GO:0061459	L-arginine transmembrane transporter activity	1/3469	13/18639	0.0769230769230769	0.413309089296406	0.931308526073137	1
GO:0097157	pre-mRNA intronic binding	1/3469	13/18639	0.0769230769230769	0.413309089296406	0.931308526073137	1
GO:0140666	annealing activity	1/3469	13/18639	0.0769230769230769	0.413309089296406	0.931308526073137	1
GO:1901338	catecholamine binding	1/3469	13/18639	0.0769230769230769	0.413309089296406	0.931308526073137	1
GO:0015085	calcium ion transmembrane transporter activity	21/3469	147/18639	0.142857142857143	0.767574022979039	0.931699872073418	1
GO:0032931	histone H3K56 acetyltransferase activity	2/3469	22/18639	0.0909090909090909	0.488456196441207	0.935131479356818	1
GO:0043992	histone H3K9 acetyltransferase activity	2/3469	22/18639	0.0909090909090909	0.488456196441207	0.935131479356818	1
GO:0043993	histone H3K18 acetyltransferase activity	2/3469	22/18639	0.0909090909090909	0.488456196441207	0.935131479356818	1
GO:0043994	histone H3K23 acetyltransferase activity	2/3469	22/18639	0.0909090909090909	0.488456196441207	0.935131479356818	1
GO:0043999	histone H2AK5 acetyltransferase activity	2/3469	22/18639	0.0909090909090909	0.488456196441207	0.935131479356818	1
GO:0044012	histone H2AK9 acetyltransferase activity	2/3469	22/18639	0.0909090909090909	0.488456196441207	0.935131479356818	1
GO:0044014	histone H2BK5 acetyltransferase activity	2/3469	22/18639	0.0909090909090909	0.488456196441207	0.935131479356818	1
GO:0044015	histone H2BK12 acetyltransferase activity	2/3469	22/18639	0.0909090909090909	0.488456196441207	0.935131479356818	1
GO:0044016	histone H3K4 acetyltransferase activity	2/3469	22/18639	0.0909090909090909	0.488456196441207	0.935131479356818	1
GO:0044017	histone H3K27 acetyltransferase activity	2/3469	22/18639	0.0909090909090909	0.488456196441207	0.935131479356818	1
GO:0044018	histone H3K36 acetyltransferase activity	2/3469	22/18639	0.0909090909090909	0.488456196441207	0.935131479356818	1
GO:0046972	histone H4K16 acetyltransferase activity	2/3469	22/18639	0.0909090909090909	0.488456196441207	0.935131479356818	1
GO:0140908	histone H3K122 acetyltransferase activity	2/3469	22/18639	0.0909090909090909	0.488456196441207	0.935131479356818	1
GO:0140996	histone H3 kinase activity	56/3469	357/18639	0.156862745098039	0.842826378173062	0.93598047416116	1
GO:0098918	structural constituent of synapse	3/3469	30/18639	0.1	0.537301816085327	0.936656483815852	1
GO:0008509	monoatomic anion transmembrane transporter activity	21/3469	149/18639	0.140939597315436	0.757271015959186	0.940930517487146	1
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	4/3469	38/18639	0.105263157894737	0.565580859037186	0.941339781572204	1
GO:0004065	arylsulfatase activity	1/3469	14/18639	0.0714285714285714	0.383787011489519	0.944101971958044	1
GO:0008195	phosphatidate phosphatase activity	1/3469	14/18639	0.0714285714285714	0.383787011489519	0.944101971958044	1
GO:0008331	high voltage-gated calcium channel activity	1/3469	14/18639	0.0714285714285714	0.383787011489519	0.944101971958044	1
GO:0015386	potassium:proton antiporter activity	1/3469	14/18639	0.0714285714285714	0.383787011489519	0.944101971958044	1
GO:0015926	glucosidase activity	1/3469	14/18639	0.0714285714285714	0.383787011489519	0.944101971958044	1
GO:0032454	histone H3K9 demethylase activity	1/3469	14/18639	0.0714285714285714	0.383787011489519	0.944101971958044	1
GO:0061783	peptidoglycan muralytic activity	1/3469	14/18639	0.0714285714285714	0.383787011489519	0.944101971958044	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	2/3469	23/18639	0.0869565217391304	0.46721897050898	0.945213925932178	1
GO:0005212	structural constituent of eye lens	2/3469	23/18639	0.0869565217391304	0.46721897050898	0.945213925932178	1
GO:0016493	C-C chemokine receptor activity	2/3469	23/18639	0.0869565217391304	0.46721897050898	0.945213925932178	1
GO:0044013	histone H2B acetyltransferase activity	2/3469	23/18639	0.0869565217391304	0.46721897050898	0.945213925932178	1
GO:0140103	catalytic activity, acting on a glycoprotein	2/3469	23/18639	0.0869565217391304	0.46721897050898	0.945213925932178	1
GO:0005184	neuropeptide hormone activity	3/3469	31/18639	0.0967741935483871	0.519969499437413	0.945431225259324	1
GO:0005452	solute:inorganic anion antiporter activity	3/3469	31/18639	0.0967741935483871	0.519969499437413	0.945431225259324	1
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	7/3469	60/18639	0.116666666666667	0.626852118766215	0.946812747275363	1
GO:0004252	serine-type endopeptidase activity	25/3469	176/18639	0.142045454545455	0.763212806939385	0.94987413719962	1
GO:0008378	galactosyltransferase activity	3/3469	32/18639	0.09375	0.503720452579994	0.953063984589846	1
GO:0160041	neuropeptide activity	3/3469	32/18639	0.09375	0.503720452579994	0.953063984589846	1
GO:0140938	histone H3 methyltransferase activity	5/3469	47/18639	0.106382978723404	0.571597676686518	0.953265381086406	1
GO:0019957	C-C chemokine binding	2/3469	24/18639	0.0833333333333333	0.447751513404439	0.953791583013361	1
GO:0140612	DNA damage sensor activity	2/3469	24/18639	0.0833333333333333	0.447751513404439	0.953791583013361	1
GO:0004089	carbonate dehydratase activity	1/3469	15/18639	0.0666666666666667	0.358201210723551	0.954513261046771	1
GO:0004467	long-chain fatty acid-CoA ligase activity	1/3469	15/18639	0.0666666666666667	0.358201210723551	0.954513261046771	1
GO:0005402	carbohydrate:monoatomic cation symporter activity	1/3469	15/18639	0.0666666666666667	0.358201210723551	0.954513261046771	1
GO:0008242	omega peptidase activity	1/3469	15/18639	0.0666666666666667	0.358201210723551	0.954513261046771	1
GO:0015250	water channel activity	1/3469	15/18639	0.0666666666666667	0.358201210723551	0.954513261046771	1
GO:0031005	filamin binding	1/3469	15/18639	0.0666666666666667	0.358201210723551	0.954513261046771	1
GO:0015103	inorganic anion transmembrane transporter activity	23/3469	165/18639	0.139393939393939	0.748966167876517	0.954608416493479	1
GO:0015108	chloride transmembrane transporter activity	16/3469	121/18639	0.132231404958678	0.710481740278119	0.954994004350722	1
GO:0004532	RNA exonuclease activity	4/3469	40/18639	0.1	0.537301816085327	0.955431211572866	1
GO:0071949	FAD binding	4/3469	40/18639	0.1	0.537301816085327	0.955431211572866	1
GO:0008017	microtubule binding	41/3469	276/18639	0.148550724637681	0.798165741286174	0.957911968190971	1
GO:0005254	chloride channel activity	10/3469	83/18639	0.120481927710843	0.647351585644972	0.959904666198108	1
GO:0000030	mannosyltransferase activity	2/3469	25/18639	0.08	0.429841452868262	0.961075153736313	1
GO:0015271	outward rectifier potassium channel activity	2/3469	25/18639	0.08	0.429841452868262	0.961075153736313	1
GO:0019706	protein-cysteine S-palmitoyltransferase activity	2/3469	25/18639	0.08	0.429841452868262	0.961075153736313	1
GO:0019707	protein-cysteine S-acyltransferase activity	2/3469	25/18639	0.08	0.429841452868262	0.961075153736313	1
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	2/3469	25/18639	0.08	0.429841452868262	0.961075153736313	1
GO:0106310	protein serine kinase activity	55/3469	361/18639	0.152354570637119	0.818603874922244	0.961080661213654	1
GO:0008227	G protein-coupled amine receptor activity	4/3469	41/18639	0.0975609756097561	0.524196893741783	0.961238862318521	1
GO:0001217	DNA-binding transcription repressor activity	41/3469	278/18639	0.147482014388489	0.792423541708576	0.962614654462554	1
GO:0170055	lipid transmembrane transporter activity	6/3469	56/18639	0.107142857142857	0.575680517234279	0.962756796413649	1
GO:0015385	sodium:proton antiporter activity	1/3469	16/18639	0.0625	0.33581363505333	0.962985850041013	1
GO:0022841	potassium ion leak channel activity	1/3469	16/18639	0.0625	0.33581363505333	0.962985850041013	1
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/3469	16/18639	0.0625	0.33581363505333	0.962985850041013	1
GO:0003724	RNA helicase activity	9/3469	77/18639	0.116883116883117	0.628015109710123	0.963029218105061	1
GO:0051427	hormone receptor binding	3/3469	34/18639	0.0882352941176471	0.474089837722348	0.965427725445842	1
GO:0008307	structural constituent of muscle	4/3469	42/18639	0.0952380952380952	0.511716015319359	0.966337563265559	1
GO:0008236	serine-type peptidase activity	27/3469	194/18639	0.139175257731959	0.747791187335249	0.966362897302445	1
GO:0005227	calcium-activated cation channel activity	2/3469	26/18639	0.0769230769230769	0.413309089296406	0.967249059899045	1
GO:0008066	glutamate receptor activity	2/3469	26/18639	0.0769230769230769	0.413309089296406	0.967249059899045	1
GO:0051139	metal cation:proton antiporter activity	2/3469	26/18639	0.0769230769230769	0.413309089296406	0.967249059899045	1
GO:0008484	sulfuric ester hydrolase activity	1/3469	17/18639	0.0588235294117647	0.316059891814898	0.96988066216622	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/3469	17/18639	0.0588235294117647	0.316059891814898	0.96988066216622	1
GO:0030548	acetylcholine receptor regulator activity	1/3469	17/18639	0.0588235294117647	0.316059891814898	0.96988066216622	1
GO:0141003	histone H2AX kinase activity	53/3469	354/18639	0.149717514124294	0.804434922387637	0.97015117660316	1
GO:0008186	ATP-dependent activity, acting on RNA	9/3469	79/18639	0.113924050632911	0.612115993008601	0.970248848532218	1
GO:0000175	3'-5'-RNA exonuclease activity	3/3469	35/18639	0.0857142857142857	0.460544413787423	0.970389191818237	1
GO:0005343	organic acid:sodium symporter activity	3/3469	35/18639	0.0857142857142857	0.460544413787423	0.970389191818237	1
GO:0017116	single-stranded DNA helicase activity	6/3469	58/18639	0.103448275862069	0.555829464915856	0.970981871376033	1
GO:0008395	steroid hydroxylase activity	2/3469	27/18639	0.0740740740740741	0.39800134524839	0.972473923276811	1
GO:0004674	protein serine/threonine kinase activity	66/3469	433/18639	0.152424942263279	0.818981982947612	0.972600182894817	1
GO:0042562	hormone binding	11/3469	94/18639	0.117021276595745	0.62875744435517	0.974108611752526	1
GO:0016409	palmitoyltransferase activity	3/3469	36/18639	0.0833333333333333	0.447751513404439	0.974670991314088	1
GO:0017171	serine hydrolase activity	27/3469	198/18639	0.136363636363636	0.73268429466181	0.974890454276438	1
GO:0022851	GABA-gated chloride ion channel activity	1/3469	18/18639	0.0555555555555556	0.298501008936293	0.975491444195292	1
GO:0099602	neurotransmitter receptor regulator activity	1/3469	18/18639	0.0555555555555556	0.298501008936293	0.975491444195292	1
GO:0004867	serine-type endopeptidase inhibitor activity	11/3469	95/18639	0.115789473684211	0.622138944940905	0.976669874219028	1
GO:0051119	sugar transmembrane transporter activity	2/3469	28/18639	0.0714285714285714	0.383787011489519	0.97688903389221	1
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	2/3469	28/18639	0.0714285714285714	0.383787011489519	0.97688903389221	1
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	15/3469	122/18639	0.122950819672131	0.660616986990156	0.976991013899918	1
GO:0042805	actinin binding	3/3469	37/18639	0.0810810810810811	0.435650121150265	0.978359975005638	1
GO:0015294	solute:monoatomic cation symporter activity	14/3469	116/18639	0.120689655172414	0.648467709068498	0.978367736885286	1
GO:0004890	GABA-A receptor activity	1/3469	19/18639	0.0526315789473684	0.282790429518593	0.980057266658453	1
GO:0005520	insulin-like growth factor binding	1/3469	19/18639	0.0526315789473684	0.282790429518593	0.980057266658453	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	1/3469	19/18639	0.0526315789473684	0.282790429518593	0.980057266658453	1
GO:0031420	alkali metal ion binding	1/3469	19/18639	0.0526315789473684	0.282790429518593	0.980057266658453	1
GO:0042577	lipid phosphatase activity	1/3469	19/18639	0.0526315789473684	0.282790429518593	0.980057266658453	1
GO:0042800	histone H3K4 methyltransferase activity	1/3469	19/18639	0.0526315789473684	0.282790429518593	0.980057266658453	1
GO:0046527	glucosyltransferase activity	1/3469	19/18639	0.0526315789473684	0.282790429518593	0.980057266658453	1
GO:0016417	S-acyltransferase activity	2/3469	29/18639	0.0689655172413793	0.37055297661057	0.980614724163931	1
GO:0008194	UDP-glycosyltransferase activity	18/3469	145/18639	0.124137931034483	0.666995357899027	0.982881191797835	1
GO:0005216	monoatomic ion channel activity	67/3469	448/18639	0.149553571428571	0.803554055306181	0.982971621032235	1
GO:0061749	forked DNA-dependent helicase activity	4/3469	47/18639	0.0851063829787234	0.457278141349215	0.98369003852408	1
GO:1990518	single-stranded 3'-5' DNA helicase activity	4/3469	47/18639	0.0851063829787234	0.457278141349215	0.98369003852408	1
GO:0022839	monoatomic ion-gated channel activity	2/3469	30/18639	0.0666666666666667	0.358201210723551	0.983754598474508	1
GO:0035925	mRNA 3'-UTR AU-rich region binding	2/3469	30/18639	0.0666666666666667	0.358201210723551	0.983754598474508	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	1/3469	20/18639	0.05	0.268650908042664	0.983772698557585	1
GO:0005326	neurotransmitter transmembrane transporter activity	1/3469	20/18639	0.05	0.268650908042664	0.983772698557585	1
GO:0030627	pre-mRNA 5'-splice site binding	1/3469	20/18639	0.05	0.268650908042664	0.983772698557585	1
GO:0140664	ATP-dependent DNA damage sensor activity	1/3469	20/18639	0.05	0.268650908042664	0.983772698557585	1
GO:0140767	enzyme-substrate adaptor activity	17/3469	139/18639	0.122302158273381	0.657131717514429	0.983792232947131	1
GO:0016757	glycosyltransferase activity	37/3469	267/18639	0.138576779026217	0.744575550380416	0.984323829455628	1
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	37/3469	268/18639	0.138059701492537	0.741797283401385	0.985375756923077	1
GO:0009378	four-way junction helicase activity	4/3469	48/18639	0.0833333333333333	0.447751513404439	0.985940438466674	1
GO:0036121	double-stranded DNA helicase activity	4/3469	48/18639	0.0833333333333333	0.447751513404439	0.985940438466674	1
GO:0043138	3'-5' DNA helicase activity	4/3469	48/18639	0.0833333333333333	0.447751513404439	0.985940438466674	1
GO:0015174	basic amino acid transmembrane transporter activity	1/3469	21/18639	0.0476190476190476	0.25585800765968	0.986796089110447	1
GO:0051428	peptide hormone receptor binding	1/3469	21/18639	0.0476190476190476	0.25585800765968	0.986796089110447	1
GO:0046943	carboxylic acid transmembrane transporter activity	24/3469	188/18639	0.127659574468085	0.685917212023822	0.987777791584087	1
GO:0015106	bicarbonate transmembrane transporter activity	2/3469	32/18639	0.0625	0.33581363505333	0.988619830073453	1
GO:0005342	organic acid transmembrane transporter activity	24/3469	189/18639	0.126984126984127	0.682288020425812	0.988762916689421	1
GO:0015171	amino acid transmembrane transporter activity	11/3469	102/18639	0.107843137254902	0.57944313499398	0.989046189777152	1
GO:0005243	gap junction channel activity	1/3469	22/18639	0.0454545454545455	0.244228098220603	0.989256308622524	1
GO:0050321	tau-protein kinase activity	1/3469	22/18639	0.0454545454545455	0.244228098220603	0.989256308622524	1
GO:0005261	monoatomic cation channel activity	48/3469	341/18639	0.140762463343109	0.756319271908965	0.989490613990107	1
GO:0015291	secondary active transmembrane transporter activity	39/3469	287/18639	0.13588850174216	0.730131387711769	0.99076083883374	1
GO:0005272	sodium channel activity	4/3469	51/18639	0.0784313725490196	0.421413189086531	0.991051141053625	1
GO:0016597	amino acid binding	4/3469	51/18639	0.0784313725490196	0.421413189086531	0.991051141053625	1
GO:0016917	GABA receptor activity	1/3469	23/18639	0.0434782608695652	0.23360948525449	0.991258235108449	1
GO:0008514	organic anion transmembrane transporter activity	36/3469	269/18639	0.133828996282528	0.719065627474787	0.991327955681379	1
GO:0015020	glucuronosyltransferase activity	2/3469	34/18639	0.0588235294117647	0.316059891814898	0.992052496677	1
GO:0003689	DNA clamp loader activity	19/3469	160/18639	0.11875	0.638045906601326	0.992095951418196	1
GO:0015149	hexose transmembrane transporter activity	1/3469	24/18639	0.0416666666666667	0.22387575670222	0.992887219982149	1
GO:0055056	D-glucose transmembrane transporter activity	1/3469	24/18639	0.0416666666666667	0.22387575670222	0.992887219982149	1
GO:0022832	voltage-gated channel activity	21/3469	175/18639	0.12	0.644762179302393	0.993215391266719	1
GO:0017046	peptide hormone binding	4/3469	53/18639	0.0754716981132075	0.4055108045927	0.993410993665641	1
GO:0031490	chromatin DNA binding	14/3469	128/18639	0.109375	0.587673861343327	0.993622441174915	1
GO:0004190	aspartic-type endopeptidase activity	2/3469	36/18639	0.0555555555555556	0.298501008936293	0.994465096769498	1
GO:0140713	histone chaperone activity	19/3469	164/18639	0.115853658536585	0.622483811318367	0.994612399342209	1
GO:0000510	H3-H4 histone complex chaperone activity	17/3469	151/18639	0.112582781456954	0.604909329367587	0.994945296852049	1
GO:0140584	chromatin extrusion motor activity	17/3469	151/18639	0.112582781456954	0.604909329367587	0.994945296852049	1
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	17/3469	151/18639	0.112582781456954	0.604909329367587	0.994945296852049	1
GO:0140849	ATP-dependent H2AZ histone chaperone activity	17/3469	151/18639	0.112582781456954	0.604909329367587	0.994945296852049	1
GO:0015145	monosaccharide transmembrane transporter activity	1/3469	26/18639	0.0384615384615385	0.206654544648203	0.995291269256126	1
GO:0030280	structural constituent of skin epidermis	2/3469	37/18639	0.0540540540540541	0.290433414100177	0.995385389441719	1
GO:0070001	aspartic-type peptidase activity	2/3469	37/18639	0.0540540540540541	0.290433414100177	0.995385389441719	1
GO:0015616	DNA translocase activity	17/3469	152/18639	0.111842105263158	0.600929662727011	0.995434024755736	1
GO:0140674	ATP-dependent histone chaperone activity	17/3469	152/18639	0.111842105263158	0.600929662727011	0.995434024755736	1
GO:0005244	voltage-gated monoatomic ion channel activity	20/3469	173/18639	0.115606936416185	0.621158168884771	0.995657394245902	1
GO:0099095	ligand-gated monoatomic anion channel activity	3/3469	47/18639	0.0638297872340425	0.342958606011911	0.99576142794494	1
GO:0015293	symporter activity	16/3469	146/18639	0.10958904109589	0.588823908038715	0.995849626095819	1
GO:0061775	cohesin loader activity	17/3469	153/18639	0.111111111111111	0.597002017872586	0.995878255698963	1
GO:0035403	histone H3T6 kinase activity	31/3469	247/18639	0.125506072874494	0.67434640885203	0.996062201568189	1
GO:0005385	zinc ion transmembrane transporter activity	1/3469	27/18639	0.037037037037037	0.199000672624195	0.996168859486099	1
GO:0015101	organic cation transmembrane transporter activity	7/3469	81/18639	0.0864197530864197	0.464334902789789	0.99617366639952	1
GO:0032266	phosphatidylinositol-3-phosphate binding	3/3469	48/18639	0.0625	0.33581363505333	0.996416160576824	1
GO:0003678	DNA helicase activity	6/3469	74/18639	0.0810810810810811	0.435650121150265	0.996638968981187	1
GO:0005242	inward rectifier potassium channel activity	1/3469	28/18639	0.0357142857142857	0.19189350574476	0.996882927100688	1
GO:0051393	alpha-actinin binding	1/3469	28/18639	0.0357142857142857	0.19189350574476	0.996882927100688	1
GO:0141052	histone H3 demethylase activity	1/3469	28/18639	0.0357142857142857	0.19189350574476	0.996882927100688	1
GO:0140097	catalytic activity, acting on DNA	44/3469	336/18639	0.130952380952381	0.703609521064119	0.997429718189064	1
GO:0140658	ATP-dependent chromatin remodeler activity	17/3469	158/18639	0.107594936708861	0.578109548952567	0.997553327797252	1
GO:0035402	histone H3T11 kinase activity	30/3469	247/18639	0.121457489878543	0.652593298889061	0.997752122713563	1
GO:0032452	histone demethylase activity	1/3469	30/18639	0.0333333333333333	0.179100605361776	0.99793667006822	1
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	29/3469	243/18639	0.119341563786008	0.641224389566851	0.998220521852722	1
GO:0140457	protein demethylase activity	1/3469	31/18639	0.032258064516129	0.173323166479138	0.998321306079469	1
GO:0004386	helicase activity	16/3469	155/18639	0.103225806451613	0.554634132733241	0.998425419571377	1
GO:0016758	hexosyltransferase activity	22/3469	197/18639	0.111675126903553	0.600032484968386	0.998428634566547	1
GO:0004676	3-phosphoinositide-dependent protein kinase activity	29/3469	245/18639	0.118367346938776	0.635989904754061	0.998514945229381	1
GO:0004711	ribosomal protein S6 kinase activity	29/3469	245/18639	0.118367346938776	0.635989904754061	0.998514945229381	1
GO:0035175	histone H3S10 kinase activity	29/3469	245/18639	0.118367346938776	0.635989904754061	0.998514945229381	1
GO:0035979	histone H2AXS139 kinase activity	29/3469	245/18639	0.118367346938776	0.635989904754061	0.998514945229381	1
GO:0044022	histone H3S28 kinase activity	29/3469	245/18639	0.118367346938776	0.635989904754061	0.998514945229381	1
GO:0044023	histone H4S1 kinase activity	29/3469	245/18639	0.118367346938776	0.635989904754061	0.998514945229381	1
GO:0044024	histone H2AS1 kinase activity	29/3469	245/18639	0.118367346938776	0.635989904754061	0.998514945229381	1
GO:0044025	histone H2BS14 kinase activity	29/3469	245/18639	0.118367346938776	0.635989904754061	0.998514945229381	1
GO:0072354	histone H3T3 kinase activity	29/3469	245/18639	0.118367346938776	0.635989904754061	0.998514945229381	1
GO:0072371	histone H2AS121 kinase activity	29/3469	245/18639	0.118367346938776	0.635989904754061	0.998514945229381	1
GO:0072518	Rho-dependent protein serine/threonine kinase activity	29/3469	245/18639	0.118367346938776	0.635989904754061	0.998514945229381	1
GO:0140823	histone H2BS36 kinase activity	29/3469	245/18639	0.118367346938776	0.635989904754061	0.998514945229381	1
GO:0140855	histone H3S57 kinase activity	29/3469	245/18639	0.118367346938776	0.635989904754061	0.998514945229381	1
GO:0140995	histone H2A kinase activity	29/3469	245/18639	0.118367346938776	0.635989904754061	0.998514945229381	1
GO:0140997	histone H4 kinase activity	29/3469	245/18639	0.118367346938776	0.635989904754061	0.998514945229381	1
GO:0140998	histone H2B kinase activity	29/3469	245/18639	0.118367346938776	0.635989904754061	0.998514945229381	1
GO:1990244	histone H2AT120 kinase activity	29/3469	245/18639	0.118367346938776	0.635989904754061	0.998514945229381	1
GO:0004677	DNA-dependent protein kinase activity	29/3469	246/18639	0.117886178861789	0.633404579937987	0.998644319454223	1
GO:0140857	histone H3T45 kinase activity	29/3469	246/18639	0.117886178861789	0.633404579937987	0.998644319454223	1
GO:0004679	AMP-activated protein kinase activity	29/3469	248/18639	0.116935483870968	0.628296478486875	0.998871830331995	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	3/3469	56/18639	0.0535714285714286	0.28784025861714	0.99908640017572	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/3469	34/18639	0.0294117647058824	0.158029945907449	0.999096042636548	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	2/3469	46/18639	0.0434782608695652	0.23360948525449	0.99912306569135	1
GO:0015370	solute:sodium symporter activity	5/3469	79/18639	0.0632911392405063	0.340064440560334	0.999558992324369	1
GO:0008094	ATP-dependent activity, acting on DNA	22/3469	210/18639	0.104761904761905	0.562887616851295	0.999588147436675	1
GO:0015079	potassium ion transmembrane transporter activity	15/3469	160/18639	0.09375	0.503720452579994	0.999618151124843	1
GO:0004497	monooxygenase activity	8/3469	106/18639	0.0754716981132075	0.4055108045927	0.999639969325997	1
GO:0005179	hormone activity	11/3469	132/18639	0.0833333333333333	0.447751513404439	0.999722769380332	1
GO:0022824	transmitter-gated monoatomic ion channel activity	3/3469	63/18639	0.0476190476190476	0.25585800765968	0.99973185366222	1
GO:0022835	transmitter-gated channel activity	3/3469	63/18639	0.0476190476190476	0.25585800765968	0.99973185366222	1
GO:0032451	demethylase activity	1/3469	40/18639	0.025	0.134325454021332	0.999737966783173	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	2/3469	53/18639	0.0377358490566038	0.20275540229635	0.999764612143291	1
GO:0022843	voltage-gated monoatomic cation channel activity	12/3469	143/18639	0.0839160839160839	0.450882642868806	0.999817055640477	1
GO:0003823	antigen binding	16/3469	174/18639	0.0919540229885057	0.494070635480761	0.999826010386739	1
GO:0099094	ligand-gated monoatomic cation channel activity	11/3469	136/18639	0.0808823529411765	0.434582351245485	0.999837388124437	1
GO:0022836	gated channel activity	36/3469	318/18639	0.113207547169811	0.60826620688905	0.999864635746009	1
GO:0030594	neurotransmitter receptor activity	6/3469	97/18639	0.0618556701030928	0.332351638815666	0.999893897570193	1
GO:0015276	ligand-gated monoatomic ion channel activity	17/3469	186/18639	0.0913978494623656	0.491082305024224	0.999898984074851	1
GO:0098960	postsynaptic neurotransmitter receptor activity	3/3469	69/18639	0.0434782608695652	0.23360948525449	0.999907898364461	1
GO:0015081	sodium ion transmembrane transporter activity	14/3469	164/18639	0.0853658536585366	0.45867228202406	0.999909431125301	1
GO:0005267	potassium channel activity	9/3469	124/18639	0.0725806451612903	0.38997712457806	0.999910297982645	1
GO:0022834	ligand-gated channel activity	17/3469	188/18639	0.0904255319148936	0.485858025183541	0.999920772574274	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	16/3469	181/18639	0.0883977900552486	0.474962931346146	0.999926274136217	1
GO:0001653	peptide receptor activity	9/3469	128/18639	0.0703125	0.377790339434996	0.999949712428092	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	3/3469	73/18639	0.0410958904109589	0.220808965514518	0.999955181050912	1
GO:0008528	G protein-coupled peptide receptor activity	8/3469	122/18639	0.0655737704918033	0.352329059728083	0.999965667245653	1
GO:0005249	voltage-gated potassium channel activity	5/3469	98/18639	0.0510204081632653	0.274133579635371	0.999980160197339	1
GO:0046873	metal ion transmembrane transporter activity	49/3469	450/18639	0.108888888888889	0.585061977515134	0.999997846301811	1
GO:0003730	mRNA 3'-UTR binding	20/3469	262/18639	0.0763358778625954	0.410154058080402	0.999999882473679	1
GO:0030527	structural constituent of chromatin	1/3469	98/18639	0.0102040816326531	0.0548267159270742	0.999999998379132	1
GO:0045182	translation regulator activity	19/3469	356/18639	0.0533707865168539	0.286762205214079	0.999999999999969	1
GO:0030371	translation repressor activity	10/3469	329/18639	0.0303951367781155	0.163313621910434	1	1