ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	73/1183	175/18639	0.417142857142857	6.5723801473252	2.41169069232783e-41	2.64080130809898e-38
GO:0015078	proton transmembrane transporter activity	56/1183	185/18639	0.302702702702703	4.76929473852551	1.0538209042981e-23	5.76966945103208e-21
GO:0022853	active monoatomic ion transmembrane transporter activity	43/1183	118/18639	0.364406779661017	5.7414860237546	4.75308991201985e-22	1.73487781788724e-19
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	33/1183	68/18639	0.485294117647059	7.64615135995227	6.3458341985093e-22	1.73717211184192e-19
GO:0009055	electron transfer activity	41/1183	116/18639	0.353448275862069	5.56882706153263	1.64721288313025e-20	3.60739621405525e-18
GO:0015399	primary active transmembrane transporter activity	44/1183	166/18639	0.265060240963855	4.17621118455224	1.74848967535381e-16	3.1909936575207e-14
GO:0003954	NADH dehydrogenase activity	22/1183	44/18639	0.5	7.87785291631445	2.05267779819458e-15	3.21097455574724e-13
GO:0008137	NADH dehydrogenase (ubiquinone) activity	21/1183	41/18639	0.51219512195122	8.06999567037091	4.7646781269167e-15	6.52165318621724e-13
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	22/1183	58/18639	0.379310344827586	5.97630221237648	2.32289050019435e-12	2.82618344190313e-10
GO:0016651	oxidoreductase activity, acting on NAD(P)H	25/1183	88/18639	0.284090909090909	4.47605279336049	1.13691849569584e-10	1.24492575278695e-08
GO:0005178	integrin binding	33/1183	161/18639	0.204968944099379	3.22943038805437	1.6618358861129e-09	1.65428208663057e-07
GO:0030695	GTPase regulator activity	67/1183	489/18639	0.137014314928425	2.15875724087145	1.94537413081717e-09	1.77515389437067e-07
GO:0060589	nucleoside-triphosphatase regulator activity	67/1183	490/18639	0.136734693877551	2.15435161384926	2.11834191577866e-09	1.78429569059818e-07
GO:0005201	extracellular matrix structural constituent	33/1183	168/18639	0.196428571428571	3.09487078855211	5.14654286513336e-09	4.0253317409436e-07
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	10/1183	18/18639	0.555555555555556	8.75316990701606	2.79710228278546e-08	2.04188466643339e-06
GO:0004129	cytochrome-c oxidase activity	9/1183	15/18639	0.6	9.45342349957735	5.72972583071317e-08	3.92128111539432e-06
GO:0022804	active transmembrane transporter activity	60/1183	457/18639	0.131291028446389	2.06858282266463	6.56643707191842e-08	4.22955799632392e-06
GO:0016675	oxidoreductase activity, acting on a heme group of donors	9/1183	16/18639	0.5625	8.86258453085376	1.23563006243941e-07	7.51674954650644e-06
GO:0019838	growth factor binding	26/1183	136/18639	0.191176470588235	3.01212023270847	3.72220117888245e-07	2.14516331098752e-05
GO:0038187	pattern recognition receptor activity	14/1183	48/18639	0.291666666666667	4.59541420118343	1.00047522530062e-06	5.27325083091286e-05
GO:1990948	ubiquitin ligase inhibitor activity	7/1183	11/18639	0.636363636363636	10.0263582571275	1.07314563983229e-06	5.27325083091286e-05
GO:0031386	protein tag activity	8/1183	15/18639	0.533333333333333	8.40304311073542	1.10762346220087e-06	5.27325083091286e-05
GO:0141047	molecular tag activity	8/1183	15/18639	0.533333333333333	8.40304311073542	1.10762346220087e-06	5.27325083091286e-05
GO:0019843	rRNA binding	16/1183	65/18639	0.246153846153846	3.87832758957019	2.10695127235145e-06	9.61296518010348e-05
GO:0001664	G protein-coupled receptor binding	41/1183	297/18639	0.138047138047138	2.17503009810702	2.21244762895952e-06	9.69052061484271e-05
GO:0015252	proton channel activity	10/1183	27/18639	0.37037037037037	5.83544660467737	3.18258182046551e-06	0.000134035657438836
GO:0035325	Toll-like receptor binding	7/1183	13/18639	0.538461538461538	8.4838416021848	4.9833509714895e-06	0.000202102567177074
GO:0016504	peptidase activator activity	14/1183	57/18639	0.245614035087719	3.8698224852071	9.32364299544943e-06	0.0003524299448712
GO:0005085	guanyl-nucleotide exchange factor activity	33/1183	230/18639	0.143478260869565	2.26060127163806	9.33376109704547e-06	0.0003524299448712
GO:0055105	ubiquitin-protein transferase inhibitor activity	7/1183	15/18639	0.466666666666667	7.35266272189349	1.6691927825927e-05	0.000609255365646335
GO:0005096	GTPase activator activity	36/1183	271/18639	0.132841328413284	2.09300889289535	2.12591049925954e-05	0.000750926450544902
GO:0019864	IgG binding	6/1183	11/18639	0.545454545454545	8.59402136325213	2.26080582806581e-05	0.000773619494291269
GO:0005126	cytokine receptor binding	36/1183	275/18639	0.130909090909091	2.06256512718051	2.92326529404182e-05	0.000969992574841149
GO:0038024	cargo receptor activity	14/1183	65/18639	0.215384615384615	3.39353664087392	4.58923962325554e-05	0.00147800511396024
GO:0001540	amyloid-beta binding	16/1183	83/18639	0.192771084337349	3.03724449785618	5.70699127287021e-05	0.00178547298394082
GO:0016209	antioxidant activity	16/1183	86/18639	0.186046511627907	2.93129410839608	8.91640989500912e-05	0.00271207467639861
GO:0031625	ubiquitin protein ligase binding	37/1183	302/18639	0.122516556291391	1.93033482055387	9.47712319481102e-05	0.00280471618873461
GO:0061134	peptidase regulator activity	30/1183	226/18639	0.132743362831858	2.09146537601269	0.000101671471760033	0.00292974372571674
GO:0019955	cytokine binding	22/1183	144/18639	0.152777777777778	2.40712172442942	0.000108871164228239	0.00305676730333134
GO:0019763	immunoglobulin receptor activity	6/1183	14/18639	0.428571428571429	6.75244535684096	0.000124503006713951	0.0034082698087944
GO:0005539	glycosaminoglycan binding	31/1183	242/18639	0.128099173553719	2.01829289591527	0.000152202551933469	0.0040649218138329
GO:0031720	haptoglobin binding	5/1183	10/18639	0.5	7.87785291631445	0.000196619060207676	0.00512613978398585
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	12/1183	59/18639	0.203389830508475	3.20455033883978	0.000280079504665143	0.00713225715368212
GO:0017124	SH3 domain binding	18/1183	115/18639	0.156521739130435	2.46611047815061	0.000328739533894642	0.00804904873602904
GO:0004857	enzyme inhibitor activity	45/1183	416/18639	0.108173076923077	1.70434317901034	0.000330782824768317	0.00804904873602904
GO:0044389	ubiquitin-like protein ligase binding	37/1183	322/18639	0.114906832298137	1.81043824784866	0.000345350803381221	0.00822085064570516
GO:0046332	SMAD binding	14/1183	79/18639	0.177215189873418	2.79215040071905	0.000408049980728385	0.00950669635952302
GO:0005125	cytokine activity	29/1183	234/18639	0.123931623931624	1.95263021002666	0.000428060409727711	0.00972082209898356
GO:0015278	intracellularly gated calcium channel activity	6/1183	17/18639	0.352941176470588	5.56083735269256	0.000434995692100634	0.00972082209898356
GO:0005518	collagen binding	13/1183	72/18639	0.180555555555556	2.84478021978022	0.000539274206840333	0.0107827568869013
GO:0042625	ATPase-coupled ion transmembrane transporter activity	7/1183	24/18639	0.291666666666667	4.59541420118343	0.00054159966098591	0.0107827568869013
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	7/1183	24/18639	0.291666666666667	4.59541420118343	0.00054159966098591	0.0107827568869013
GO:0046961	proton-transporting ATPase activity, rotational mechanism	7/1183	24/18639	0.291666666666667	4.59541420118343	0.00054159966098591	0.0107827568869013
GO:0048027	mRNA 5'-UTR binding	7/1183	24/18639	0.291666666666667	4.59541420118343	0.00054159966098591	0.0107827568869013
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	7/1183	24/18639	0.291666666666667	4.59541420118343	0.00054159966098591	0.0107827568869013
GO:0004601	peroxidase activity	11/1183	57/18639	0.192982456140351	3.04057480980558	0.000795230300715292	0.0155495924872008
GO:0005035	death receptor activity	5/1183	13/18639	0.384615384615385	6.05988685870343	0.000855032236991457	0.0158988622935279
GO:0070700	BMP receptor binding	5/1183	13/18639	0.384615384615385	6.05988685870343	0.000855032236991457	0.0158988622935279
GO:0140311	protein sequestering activity	8/1183	33/18639	0.242424242424242	3.81956505033428	0.000856651027687805	0.0158988622935279
GO:0050840	extracellular matrix binding	12/1183	67/18639	0.17910447761194	2.8219174625604	0.000939313726747023	0.0171424755131332
GO:0044325	transmembrane transporter binding	19/1183	136/18639	0.139705882352941	2.2011647854408	0.000968615423288837	0.0173874407951029
GO:0033218	amide binding	29/1183	247/18639	0.117408906882591	1.84986019897262	0.00102727807909203	0.0181430563968673
GO:0016505	peptidase activator activity involved in apoptotic process	6/1183	20/18639	0.3	4.72671174978867	0.00115572554909997	0.0200876107343565
GO:0005044	scavenger receptor activity	7/1183	27/18639	0.259259259259259	4.08481262327416	0.00117544988922545	0.0201112129484667
GO:0005344	oxygen carrier activity	5/1183	14/18639	0.357142857142857	5.62703779736747	0.00126088180936785	0.0212410089424276
GO:0005080	protein kinase C binding	10/1183	52/18639	0.192307692307692	3.02994342935171	0.00139943199023009	0.0232178489288173
GO:0015026	coreceptor activity	11/1183	61/18639	0.180327868852459	2.84119285506423	0.00142871415588426	0.0233498806073621
GO:0030020	extracellular matrix structural constituent conferring tensile strength	9/1183	44/18639	0.204545454545455	3.22275801121955	0.0015256784439914	0.0245679102378026
GO:0008009	chemokine activity	9/1183	45/18639	0.2	3.15114116652578	0.00180145199383164	0.0285882599021107
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	10/1183	54/18639	0.185185185185185	2.91772330233869	0.00188693714158922	0.0295170881434313
GO:0061133	endopeptidase activator activity	6/1183	22/18639	0.272727272727273	4.29701068162607	0.00199446586878363	0.0307597200889869
GO:0033612	receptor serine/threonine kinase binding	7/1183	30/18639	0.233333333333333	3.67633136094675	0.00228066879067786	0.0346851711915592
GO:0002020	protease binding	18/1183	136/18639	0.132352941176471	2.08531400725971	0.00240718471341841	0.0361077707012762
GO:0005031	tumor necrosis factor receptor activity	4/1183	10/18639	0.4	6.30228233305156	0.00248786231359927	0.0368136382890702
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	5/1183	17/18639	0.294117647058824	4.6340311272438	0.00332220368449082	0.0478659609804927
GO:0030169	low-density lipoprotein particle binding	5/1183	17/18639	0.294117647058824	4.6340311272438	0.00332220368449082	0.0478659609804927
GO:0003779	actin binding	43/1183	443/18639	0.0970654627539503	1.52933487765924	0.00368486851797702	0.0507823617459547
GO:0001851	complement component C3b binding	4/1183	11/18639	0.363636363636364	5.72934757550142	0.00371428179081016	0.0507823617459547
GO:0034713	type I transforming growth factor beta receptor binding	4/1183	11/18639	0.363636363636364	5.72934757550142	0.00371428179081016	0.0507823617459547
GO:0048407	platelet-derived growth factor binding	4/1183	11/18639	0.363636363636364	5.72934757550142	0.00371428179081016	0.0507823617459547
GO:0042169	SH2 domain binding	8/1183	41/18639	0.195121951219512	3.0742840649032	0.00375650347161856	0.0507823617459547
GO:0035615	clathrin adaptor activity	5/1183	18/18639	0.277777777777778	4.37658495350803	0.00436242195855983	0.0582542932271099
GO:0140297	DNA-binding transcription factor binding	46/1183	488/18639	0.0942622950819672	1.48516899241994	0.00473707020514147	0.0624950828268663
GO:0019865	immunoglobulin binding	6/1183	26/18639	0.230769230769231	3.63593211522206	0.00495064741110288	0.0645352251804482
GO:0004875	complement receptor activity	4/1183	12/18639	0.333333333333333	5.25190194420964	0.00529387788295896	0.0674046079283728
GO:0035497	cAMP response element binding	4/1183	12/18639	0.333333333333333	5.25190194420964	0.00529387788295896	0.0674046079283728
GO:0004364	glutathione transferase activity	6/1183	27/18639	0.222222222222222	3.50126796280642	0.00602927527449643	0.0758857060410757
GO:0051117	ATPase binding	12/1183	84/18639	0.142857142857143	2.25081511894699	0.00658808396477418	0.0819767266071333
GO:0055106	ubiquitin-protein transferase regulator activity	7/1183	36/18639	0.194444444444444	3.06360946745562	0.00671063220726087	0.0824162615068676
GO:0004715	non-membrane spanning protein tyrosine kinase activity	8/1183	45/18639	0.177777777777778	2.80101437024514	0.00677393930193432	0.0824162615068676
GO:0035673	oligopeptide transmembrane transporter activity	4/1183	13/18639	0.307692307692308	4.84790948696274	0.00726669817005564	0.0853899478964694
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	4/1183	13/18639	0.307692307692308	4.84790948696274	0.00726669817005564	0.0853899478964694
GO:0046875	ephrin receptor binding	6/1183	28/18639	0.214285714285714	3.37622267842048	0.00726933221125569	0.0853899478964694
GO:0140313	molecular sequestering activity	9/1183	55/18639	0.163636363636364	2.57820640897564	0.00733027863220833	0.0853899478964694
GO:0004713	protein tyrosine kinase activity	17/1183	140/18639	0.121428571428571	1.91319285110494	0.00752218191485236	0.0867030441764562
GO:0045296	cadherin binding	33/1183	334/18639	0.0988023952095808	1.5567014744813	0.00781991212235887	0.0878134242620325
GO:0043394	proteoglycan binding	7/1183	37/18639	0.189189189189189	2.98080921157844	0.00783295366055278	0.0878134242620325
GO:0035091	phosphatidylinositol binding	29/1183	284/18639	0.102112676056338	1.60885728572619	0.0078591009841819	0.0878134242620325
GO:0099604	ligand-gated calcium channel activity	6/1183	29/18639	0.206896551724138	3.25980120675081	0.00868349418136898	0.0949247982262803
GO:0008081	phosphoric diester hydrolase activity	12/1183	87/18639	0.137931034482759	2.17320080450054	0.00869575293221936	0.0949247982262803
GO:0001846	opsonin binding	5/1183	21/18639	0.238095238095238	3.75135853157831	0.00884230997176309	0.0949247982262803
GO:0140312	cargo adaptor activity	5/1183	21/18639	0.238095238095238	3.75135853157831	0.00884230997176309	0.0949247982262803
GO:0051020	GTPase binding	31/1183	315/18639	0.0984126984126984	1.5505615263857	0.0102539192264566	0.108280765185584
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	6/1183	30/18639	0.2	3.15114116652578	0.0102842005290418	0.108280765185584
GO:0030021	extracellular matrix structural constituent conferring compression resistance	5/1183	22/18639	0.227272727272727	3.58084223468839	0.0108563817667571	0.112148472024519
GO:0031683	G-protein beta/gamma-subunit complex binding	5/1183	22/18639	0.227272727272727	3.58084223468839	0.0108563817667571	0.112148472024519
GO:0019210	kinase inhibitor activity	12/1183	90/18639	0.133333333333333	2.10076077768385	0.0112953483167962	0.115592583241979
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	7/1183	40/18639	0.175	2.75724852071006	0.0120291859510918	0.121389856798287
GO:0070325	lipoprotein particle receptor binding	6/1183	31/18639	0.193548387096774	3.04949145147656	0.0120835565214733	0.121389856798287
GO:0005041	low-density lipoprotein particle receptor activity	4/1183	15/18639	0.266666666666667	4.20152155536771	0.0125329849070333	0.122532307796441
GO:0005523	tropomyosin binding	4/1183	15/18639	0.266666666666667	4.20152155536771	0.0125329849070333	0.122532307796441
GO:0016846	carbon-sulfur lyase activity	4/1183	15/18639	0.266666666666667	4.20152155536771	0.0125329849070333	0.122532307796441
GO:0008201	heparin binding	19/1183	172/18639	0.11046511627907	1.74045587686017	0.0130973571348794	0.123185285279419
GO:0001618	virus receptor activity	11/1183	81/18639	0.135802469135802	2.13966375504837	0.0131010480597475	0.123185285279419
GO:0061135	endopeptidase regulator activity	20/1183	184/18639	0.108695652173913	1.71257672093793	0.0131221352515801	0.123185285279419
GO:0004602	glutathione peroxidase activity	5/1183	23/18639	0.217391304347826	3.42515344187585	0.0131622633586229	0.123185285279419
GO:0031681	G-protein beta-subunit binding	5/1183	23/18639	0.217391304347826	3.42515344187585	0.0131622633586229	0.123185285279419
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	7/1183	41/18639	0.170731707317073	2.6899985567903	0.013732385285101	0.126510228657157
GO:0071813	lipoprotein particle binding	6/1183	32/18639	0.1875	2.95419484361792	0.0140932417755954	0.126510228657157
GO:0071814	protein-lipid complex binding	6/1183	32/18639	0.1875	2.95419484361792	0.0140932417755954	0.126510228657157
GO:0035401	histone H3Y41 kinase activity	14/1183	115/18639	0.121739130434783	1.91808592745048	0.0141294274271034	0.126510228657157
GO:0140801	histone H2AXY142 kinase activity	14/1183	115/18639	0.121739130434783	1.91808592745048	0.0141294274271034	0.126510228657157
GO:0140272	exogenous protein binding	11/1183	82/18639	0.134146341463415	2.11357029462095	0.0142905747212301	0.126510228657157
GO:0005021	vascular endothelial growth factor receptor activity	8/1183	51/18639	0.156862745098039	2.47148326786336	0.0143262724689384	0.126510228657157
GO:0008083	growth factor activity	18/1183	162/18639	0.111111111111111	1.75063398140321	0.0146205507615187	0.127867586798095
GO:0042826	histone deacetylase binding	15/1183	127/18639	0.118110236220472	1.86091013771208	0.0147135305356712	0.127867586798095
GO:0042379	chemokine receptor binding	10/1183	72/18639	0.138888888888889	2.18829247675402	0.015138908491525	0.130528384237952
GO:0042277	peptide binding	25/1183	249/18639	0.100401606425703	1.58189817596676	0.0156811371048724	0.131784120372733
GO:0005540	hyaluronic acid binding	5/1183	24/18639	0.208333333333333	3.28243871513102	0.0157769613930698	0.131784120372733
GO:0005324	long-chain fatty acid transmembrane transporter activity	4/1183	16/18639	0.25	3.93892645815723	0.0158863049216445	0.131784120372733
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	4/1183	16/18639	0.25	3.93892645815723	0.0158863049216445	0.131784120372733
GO:0070411	I-SMAD binding	4/1183	16/18639	0.25	3.93892645815723	0.0158863049216445	0.131784120372733
GO:1901681	sulfur compound binding	27/1183	275/18639	0.0981818181818182	1.54692384538538	0.0162344728997029	0.13365975808402
GO:0004860	protein kinase inhibitor activity	11/1183	84/18639	0.130952380952381	2.06324719236807	0.0169116477724125	0.138195927692475
GO:0016798	hydrolase activity, acting on glycosyl bonds	15/1183	130/18639	0.115384615384615	1.81796605761103	0.0178986119891467	0.145177630578634
GO:0001848	complement binding	5/1183	25/18639	0.2	3.15114116652578	0.0187160421103397	0.150164363804975
GO:0051427	hormone receptor binding	6/1183	34/18639	0.176470588235294	2.78041867634628	0.0187876875262846	0.150164363804975
GO:0008429	phosphatidylethanolamine binding	4/1183	17/18639	0.235294117647059	3.70722490179504	0.0197521822253841	0.156729272005765
GO:0030246	carbohydrate binding	27/1183	280/18639	0.0964285714285714	1.51930020528922	0.0200439264295011	0.157899995973408
GO:0140375	immune receptor activity	17/1183	156/18639	0.108974358974359	1.7169679432993	0.0205688673973088	0.160877927143237
GO:0005131	growth hormone receptor binding	3/1183	10/18639	0.3	4.72671174978867	0.0218496999754314	0.167242369148672
GO:0005381	iron ion transmembrane transporter activity	3/1183	10/18639	0.3	4.72671174978867	0.0218496999754314	0.167242369148672
GO:0005160	transforming growth factor beta receptor binding	5/1183	26/18639	0.192307692307692	3.02994342935171	0.0219935170387295	0.167242369148672
GO:0050750	low-density lipoprotein particle receptor binding	5/1183	26/18639	0.192307692307692	3.02994342935171	0.0219935170387295	0.167242369148672
GO:0003746	translation elongation factor activity	4/1183	18/18639	0.222222222222222	3.50126796280642	0.0241492565873339	0.180417956641985
GO:0030228	lipoprotein particle receptor activity	4/1183	18/18639	0.222222222222222	3.50126796280642	0.0241492565873339	0.180417956641985
GO:0005543	phospholipid binding	43/1183	497/18639	0.0865191146881288	1.36316971992564	0.024220492809472	0.180417956641985
GO:0030276	clathrin binding	7/1183	46/18639	0.152173913043478	2.3976074093131	0.02488688635827	0.183847626451081
GO:0051015	actin filament binding	21/1183	209/18639	0.100478468899522	1.58310919849381	0.0250167089874074	0.183847626451081
GO:0019199	transmembrane receptor protein kinase activity	10/1183	78/18639	0.128205128205128	2.01996228623448	0.0253140475565144	0.184792547162555
GO:0023026	MHC class II protein complex binding	5/1183	27/18639	0.185185185185185	2.91772330233869	0.0256217538033279	0.185800135196318
GO:1901981	phosphatidylinositol phosphate binding	19/1183	185/18639	0.102702702702703	1.61815357199973	0.0261672168236556	0.188507252775677
GO:0005504	fatty acid binding	7/1183	47/18639	0.148936170212766	2.34659448571069	0.0276954003159779	0.197309921793443
GO:0008046	axon guidance receptor activity	3/1183	11/18639	0.272727272727273	4.29701068162607	0.0286504817946643	0.197309921793443
GO:0010854	adenylate cyclase regulator activity	3/1183	11/18639	0.272727272727273	4.29701068162607	0.0286504817946643	0.197309921793443
GO:0042608	T cell receptor binding	3/1183	11/18639	0.272727272727273	4.29701068162607	0.0286504817946643	0.197309921793443
GO:0050786	RAGE receptor binding	3/1183	11/18639	0.272727272727273	4.29701068162607	0.0286504817946643	0.197309921793443
GO:0097493	structural molecule activity conferring elasticity	3/1183	11/18639	0.272727272727273	4.29701068162607	0.0286504817946643	0.197309921793443
GO:0140031	phosphorylation-dependent protein binding	3/1183	11/18639	0.272727272727273	4.29701068162607	0.0286504817946643	0.197309921793443
GO:0015245	fatty acid transmembrane transporter activity	4/1183	19/18639	0.210526315789474	3.31699070160609	0.0290916616797217	0.199096059620596
GO:0005109	frizzled binding	6/1183	38/18639	0.157894736842105	2.48774302620456	0.0311488196094066	0.211850667529815
GO:0003785	actin monomer binding	5/1183	29/18639	0.172413793103448	2.71650100562567	0.0339713932732115	0.229546122401839
GO:0019208	phosphatase regulator activity	13/1183	117/18639	0.111111111111111	1.75063398140321	0.0344276217817205	0.229546122401839
GO:0001614	purinergic nucleotide receptor activity	4/1183	20/18639	0.2	3.15114116652578	0.034589141731784	0.229546122401839
GO:0016502	nucleotide receptor activity	4/1183	20/18639	0.2	3.15114116652578	0.034589141731784	0.229546122401839
GO:0004714	transmembrane receptor protein tyrosine kinase activity	8/1183	60/18639	0.133333333333333	2.10076077768385	0.0350213955041894	0.231014626970406
GO:0020037	heme binding	15/1183	142/18639	0.105633802816901	1.66433512316503	0.0360892850897402	0.233318350835847
GO:0010853	cyclase activator activity	3/1183	12/18639	0.25	3.93892645815723	0.0364360164318994	0.233318350835847
GO:0015132	prostaglandin transmembrane transporter activity	3/1183	12/18639	0.25	3.93892645815723	0.0364360164318994	0.233318350835847
GO:0016208	AMP binding	3/1183	12/18639	0.25	3.93892645815723	0.0364360164318994	0.233318350835847
GO:0097371	MDM2/MDM4 family protein binding	3/1183	12/18639	0.25	3.93892645815723	0.0364360164318994	0.233318350835847
GO:0008135	translation factor activity, RNA binding	10/1183	83/18639	0.120481927710843	1.89827781116011	0.0369457443740236	0.235206919125325
GO:0031267	small GTPase binding	26/1183	283/18639	0.0918727915194346	1.44752067720266	0.0373029870170404	0.236108501639649
GO:0031072	heat shock protein binding	14/1183	131/18639	0.106870229007634	1.68381589050996	0.0385166307305584	0.242389141666445
GO:0180051	translation factor activity	10/1183	84/18639	0.119047619047619	1.87567926578916	0.0396530547255926	0.248114828140137
GO:0009931	calcium-dependent protein serine/threonine kinase activity	4/1183	21/18639	0.19047619047619	3.00108682526265	0.0406472197929654	0.25146161397343
GO:0072542	protein phosphatase activator activity	4/1183	21/18639	0.19047619047619	3.00108682526265	0.0406472197929654	0.25146161397343
GO:0019207	kinase regulator activity	26/1183	287/18639	0.0905923344947735	1.42734617299077	0.0430682874467375	0.264666172297959
GO:0001530	lipopolysaccharide binding	6/1183	41/18639	0.146341463414634	2.3057130486774	0.0432650637820408	0.264666172297959
GO:0005164	tumor necrosis factor receptor binding	5/1183	31/18639	0.161290322580645	2.54124287623047	0.0438290770721554	0.265153808806686
GO:0017147	Wnt-protein binding	5/1183	31/18639	0.161290322580645	2.54124287623047	0.0438290770721554	0.265153808806686
GO:0017154	semaphorin receptor activity	3/1183	13/18639	0.230769230769231	3.63593211522206	0.0451868119104525	0.270380104054347
GO:0071714	icosanoid transmembrane transporter activity	3/1183	13/18639	0.230769230769231	3.63593211522206	0.0451868119104525	0.270380104054347
GO:0042626	ATPase-coupled transmembrane transporter activity	11/1183	98/18639	0.112244897959184	1.76849759345835	0.0461302699557206	0.274525247834316
GO:0008093	cytoskeletal anchor activity	4/1183	22/18639	0.181818181818182	2.86467378775071	0.0472674060210117	0.275662944487901
GO:0033691	sialic acid binding	4/1183	22/18639	0.181818181818182	2.86467378775071	0.0472674060210117	0.275662944487901
GO:0140517	protein-RNA adaptor activity	4/1183	22/18639	0.181818181818182	2.86467378775071	0.0472674060210117	0.275662944487901
GO:0003725	double-stranded RNA binding	9/1183	75/18639	0.12	1.89068469991547	0.0473284324782881	0.275662944487901
GO:0043425	bHLH transcription factor binding	5/1183	32/18639	0.15625	2.46182903634827	0.0493357132381851	0.285833894157739
GO:0005200	structural constituent of cytoskeleton	12/1183	112/18639	0.107142857142857	1.68811133921024	0.0518172426626016	0.297179153888822
GO:0004197	cysteine-type endopeptidase activity	10/1183	88/18639	0.113636363636364	1.79042111734419	0.0518367291258128	0.297179153888822
GO:0005158	insulin receptor binding	4/1183	23/18639	0.173913043478261	2.74012275350068	0.0544474360551989	0.305441877611543
GO:0016849	phosphorus-oxygen lyase activity	4/1183	23/18639	0.173913043478261	2.74012275350068	0.0544474360551989	0.305441877611543
GO:0005161	platelet-derived growth factor receptor binding	3/1183	14/18639	0.214285714285714	3.37622267842048	0.0548734811457585	0.305441877611543
GO:0032036	myosin heavy chain binding	3/1183	14/18639	0.214285714285714	3.37622267842048	0.0548734811457585	0.305441877611543
GO:0034236	protein kinase A catalytic subunit binding	3/1183	14/18639	0.214285714285714	3.37622267842048	0.0548734811457585	0.305441877611543
GO:0019956	chemokine binding	5/1183	33/18639	0.151515151515152	2.38722815645893	0.0552305860886626	0.305441877611543
GO:0140416	transcription regulator inhibitor activity	5/1183	33/18639	0.151515151515152	2.38722815645893	0.0552305860886626	0.305441877611543
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	30/1183	349/18639	0.0859598853868195	1.35435866756122	0.0563942455022796	0.310196545807217
GO:0019887	protein kinase regulator activity	23/1183	255/18639	0.0901960784313725	1.42110287902143	0.0566569033437839	0.310196545807217
GO:0046906	tetrapyrrole binding	15/1183	152/18639	0.0986842105263158	1.55483939137785	0.0592774915434164	0.322929618109656
GO:0019825	oxygen binding	5/1183	34/18639	0.147058823529412	2.3170155636219	0.0615138444614864	0.33036286720368
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	4/1183	24/18639	0.166666666666667	2.62595097210482	0.0621815309876247	0.33036286720368
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	4/1183	24/18639	0.166666666666667	2.62595097210482	0.0621815309876247	0.33036286720368
GO:0035035	histone acetyltransferase binding	4/1183	24/18639	0.166666666666667	2.62595097210482	0.0621815309876247	0.33036286720368
GO:0050431	transforming growth factor beta binding	4/1183	24/18639	0.166666666666667	2.62595097210482	0.0621815309876247	0.33036286720368
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	10/1183	91/18639	0.10989010989011	1.73139624534384	0.062452158457682	0.33036286720368
GO:0170055	lipid transmembrane transporter activity	7/1183	56/18639	0.125	1.96946322907861	0.0628482924460965	0.33086000109844
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	3/1183	15/18639	0.2	3.15114116652578	0.0654586052054398	0.339702240284154
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	3/1183	15/18639	0.2	3.15114116652578	0.0654586052054398	0.339702240284154
GO:0050700	CARD domain binding	3/1183	15/18639	0.2	3.15114116652578	0.0654586052054398	0.339702240284154
GO:0043178	alcohol binding	10/1183	92/18639	0.108695652173913	1.71257672093793	0.066280409977668	0.342344570403521
GO:1990782	protein tyrosine kinase binding	12/1183	117/18639	0.102564102564103	1.61596982898758	0.0677744913680011	0.348418159849583
GO:0016247	channel regulator activity	16/1183	168/18639	0.0952380952380952	1.50054341263132	0.0682049956000525	0.348992851318026
GO:0004180	carboxypeptidase activity	6/1183	46/18639	0.130434782608696	2.05509206512551	0.0692528167029277	0.352706205998632
GO:0051219	phosphoprotein binding	10/1183	93/18639	0.10752688172043	1.69416191748698	0.0702554027544418	0.35391942908321
GO:0019211	phosphatase activator activity	4/1183	25/18639	0.16	2.52091293322063	0.0704606717261551	0.35391942908321
GO:0120020	cholesterol transfer activity	4/1183	25/18639	0.16	2.52091293322063	0.0704606717261551	0.35391942908321
GO:0030414	peptidase inhibitor activity	16/1183	169/18639	0.0946745562130177	1.491664457527	0.0711210950853481	0.355605475426741
GO:0141108	transporter regulator activity	16/1183	170/18639	0.0941176470588235	1.48288996071802	0.0741190343647685	0.368910648315552
GO:0097110	scaffold protein binding	8/1183	70/18639	0.114285714285714	1.80065209515759	0.0748794655458818	0.370941461040902
GO:0001784	phosphotyrosine residue binding	6/1183	47/18639	0.127659574468085	2.01136670203773	0.0753343898327251	0.370941461040902
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	3/1183	16/18639	0.1875	2.95419484361792	0.0768983668093925	0.370941461040902
GO:0005159	insulin-like growth factor receptor binding	3/1183	16/18639	0.1875	2.95419484361792	0.0768983668093925	0.370941461040902
GO:0005521	lamin binding	3/1183	16/18639	0.1875	2.95419484361792	0.0768983668093925	0.370941461040902
GO:0015923	mannosidase activity	3/1183	16/18639	0.1875	2.95419484361792	0.0768983668093925	0.370941461040902
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	3/1183	16/18639	0.1875	2.95419484361792	0.0768983668093925	0.370941461040902
GO:0045309	protein phosphorylated amino acid binding	7/1183	59/18639	0.11864406779661	1.86932103098987	0.0787530603112834	0.374154333740988
GO:0004112	cyclic-nucleotide phosphodiesterase activity	4/1183	26/18639	0.153846153846154	2.42395474348137	0.0792728816693234	0.374154333740988
GO:0004435	phosphatidylinositol phospholipase C activity	4/1183	26/18639	0.153846153846154	2.42395474348137	0.0792728816693234	0.374154333740988
GO:0030507	spectrin binding	4/1183	26/18639	0.153846153846154	2.42395474348137	0.0792728816693234	0.374154333740988
GO:0070412	R-SMAD binding	4/1183	26/18639	0.153846153846154	2.42395474348137	0.0792728816693234	0.374154333740988
GO:0023023	MHC protein complex binding	5/1183	37/18639	0.135135135135135	2.12914943684174	0.0826711540560125	0.38851894288126
GO:0005004	GPI-linked ephrin receptor activity	6/1183	49/18639	0.122448979591837	1.92927010195456	0.0883745857310783	0.395192937983359
GO:0005008	hepatocyte growth factor receptor activity	6/1183	49/18639	0.122448979591837	1.92927010195456	0.0883745857310783	0.395192937983359
GO:0005009	insulin receptor activity	6/1183	49/18639	0.122448979591837	1.92927010195456	0.0883745857310783	0.395192937983359
GO:0005011	macrophage colony-stimulating factor receptor activity	6/1183	49/18639	0.122448979591837	1.92927010195456	0.0883745857310783	0.395192937983359
GO:0005018	platelet-derived growth factor alpha-receptor activity	6/1183	49/18639	0.122448979591837	1.92927010195456	0.0883745857310783	0.395192937983359
GO:0005020	stem cell factor receptor activity	6/1183	49/18639	0.122448979591837	1.92927010195456	0.0883745857310783	0.395192937983359
GO:0008288	boss receptor activity	6/1183	49/18639	0.122448979591837	1.92927010195456	0.0883745857310783	0.395192937983359
GO:0036332	placental growth factor receptor activity	6/1183	49/18639	0.122448979591837	1.92927010195456	0.0883745857310783	0.395192937983359
GO:0038062	protein tyrosine kinase collagen receptor activity	6/1183	49/18639	0.122448979591837	1.92927010195456	0.0883745857310783	0.395192937983359
GO:0060175	brain-derived neurotrophic factor receptor activity	6/1183	49/18639	0.122448979591837	1.92927010195456	0.0883745857310783	0.395192937983359
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	3/1183	17/18639	0.176470588235294	2.78041867634628	0.08914397779168	0.395192937983359
GO:0005092	GDP-dissociation inhibitor activity	3/1183	17/18639	0.176470588235294	2.78041867634628	0.08914397779168	0.395192937983359
GO:0019198	transmembrane receptor protein phosphatase activity	3/1183	17/18639	0.176470588235294	2.78041867634628	0.08914397779168	0.395192937983359
GO:0036041	long-chain fatty acid binding	3/1183	17/18639	0.176470588235294	2.78041867634628	0.08914397779168	0.395192937983359
GO:0000146	microfilament motor activity	5/1183	38/18639	0.131578947368421	2.0731191885038	0.0904775683661043	0.397063240790742
GO:0043531	ADP binding	5/1183	38/18639	0.131578947368421	2.0731191885038	0.0904775683661043	0.397063240790742
GO:0043539	protein serine/threonine kinase activator activity	8/1183	73/18639	0.10958904109589	1.72665269398673	0.0906537079430919	0.397063240790742
GO:0005006	epidermal growth factor receptor activity	6/1183	50/18639	0.12	1.89068469991547	0.0953275188821414	0.409347581082136
GO:0005007	fibroblast growth factor receptor activity	6/1183	50/18639	0.12	1.89068469991547	0.0953275188821414	0.409347581082136
GO:0005017	platelet-derived growth factor receptor activity	6/1183	50/18639	0.12	1.89068469991547	0.0953275188821414	0.409347581082136
GO:0005019	platelet-derived growth factor beta-receptor activity	6/1183	50/18639	0.12	1.89068469991547	0.0953275188821414	0.409347581082136
GO:0048020	CCR chemokine receptor binding	6/1183	50/18639	0.12	1.89068469991547	0.0953275188821414	0.409347581082136
GO:0051019	mitogen-activated protein kinase binding	4/1183	28/18639	0.142857142857143	2.25081511894699	0.0984355295911019	0.417071727464995
GO:0051959	dynein light intermediate chain binding	4/1183	28/18639	0.142857142857143	2.25081511894699	0.0984355295911019	0.417071727464995
GO:0097718	disordered domain specific binding	4/1183	28/18639	0.142857142857143	2.25081511894699	0.0984355295911019	0.417071727464995
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	5/1183	39/18639	0.128205128205128	2.01996228623448	0.0986498423866974	0.417071727464995
GO:0004706	JUN kinase kinase kinase activity	3/1183	18/18639	0.166666666666667	2.62595097210482	0.102142922032549	0.423801551280509
GO:0015172	acidic amino acid transmembrane transporter activity	3/1183	18/18639	0.166666666666667	2.62595097210482	0.102142922032549	0.423801551280509
GO:1990381	ubiquitin-specific protease binding	3/1183	18/18639	0.166666666666667	2.62595097210482	0.102142922032549	0.423801551280509
GO:0003743	translation initiation factor activity	6/1183	51/18639	0.117647058823529	1.85361245089752	0.102563845743685	0.423801551280509
GO:0005010	insulin-like growth factor receptor activity	6/1183	51/18639	0.117647058823529	1.85361245089752	0.102563845743685	0.423801551280509
GO:0005030	neurotrophin receptor activity	6/1183	51/18639	0.117647058823529	1.85361245089752	0.102563845743685	0.423801551280509
GO:0005507	copper ion binding	7/1183	63/18639	0.111111111111111	1.75063398140321	0.103262144035671	0.425082886161879
GO:0071855	neuropeptide receptor binding	5/1183	40/18639	0.125	1.96946322907861	0.107179361528762	0.439555808516833
GO:0098631	cell adhesion mediator activity	8/1183	76/18639	0.105263157894737	1.65849535080304	0.10819636804728	0.441040820685744
GO:0004629	phospholipase C activity	4/1183	29/18639	0.137931034482759	2.17320080450054	0.108749791401964	0.441040820685744
GO:0043236	laminin binding	4/1183	29/18639	0.137931034482759	2.17320080450054	0.108749791401964	0.441040820685744
GO:0043395	heparan sulfate proteoglycan binding	3/1183	19/18639	0.157894736842105	2.48774302620456	0.115840033348704	0.468062127368381
GO:0005003	ephrin receptor activity	6/1183	53/18639	0.113207547169811	1.78366481124101	0.11786654866282	0.469323166493773
GO:0005005	transmembrane-ephrin receptor activity	6/1183	53/18639	0.113207547169811	1.78366481124101	0.11786654866282	0.469323166493773
GO:0005246	calcium channel regulator activity	6/1183	53/18639	0.113207547169811	1.78366481124101	0.11786654866282	0.469323166493773
GO:0038064	collagen receptor activity	6/1183	53/18639	0.113207547169811	1.78366481124101	0.11786654866282	0.469323166493773
GO:0001968	fibronectin binding	4/1183	30/18639	0.133333333333333	2.10076077768385	0.119525323645029	0.474203729678647
GO:0042056	chemoattractant activity	5/1183	42/18639	0.119047619047619	1.87567926578916	0.125269951807433	0.476740389484107
GO:0048487	beta-tubulin binding	5/1183	42/18639	0.119047619047619	1.87567926578916	0.125269951807433	0.476740389484107
GO:0051879	Hsp90 protein binding	5/1183	42/18639	0.119047619047619	1.87567926578916	0.125269951807433	0.476740389484107
GO:0033293	monocarboxylic acid binding	8/1183	79/18639	0.10126582278481	1.5955145146966	0.127462257057651	0.476740389484107
GO:0004955	prostaglandin receptor activity	2/1183	10/18639	0.2	3.15114116652578	0.129124691093543	0.476740389484107
GO:0005522	profilin binding	2/1183	10/18639	0.2	3.15114116652578	0.129124691093543	0.476740389484107
GO:0008239	dipeptidyl-peptidase activity	2/1183	10/18639	0.2	3.15114116652578	0.129124691093543	0.476740389484107
GO:0016175	superoxide-generating NAD(P)H oxidase activity	2/1183	10/18639	0.2	3.15114116652578	0.129124691093543	0.476740389484107
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	2/1183	10/18639	0.2	3.15114116652578	0.129124691093543	0.476740389484107
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	2/1183	10/18639	0.2	3.15114116652578	0.129124691093543	0.476740389484107
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	2/1183	10/18639	0.2	3.15114116652578	0.129124691093543	0.476740389484107
GO:0043422	protein kinase B binding	2/1183	10/18639	0.2	3.15114116652578	0.129124691093543	0.476740389484107
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	2/1183	10/18639	0.2	3.15114116652578	0.129124691093543	0.476740389484107
GO:0070097	delta-catenin binding	2/1183	10/18639	0.2	3.15114116652578	0.129124691093543	0.476740389484107
GO:0070513	death domain binding	2/1183	10/18639	0.2	3.15114116652578	0.129124691093543	0.476740389484107
GO:0071723	lipopeptide binding	2/1183	10/18639	0.2	3.15114116652578	0.129124691093543	0.476740389484107
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	2/1183	10/18639	0.2	3.15114116652578	0.129124691093543	0.476740389484107
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	2/1183	10/18639	0.2	3.15114116652578	0.129124691093543	0.476740389484107
GO:1905394	retromer complex binding	2/1183	10/18639	0.2	3.15114116652578	0.129124691093543	0.476740389484107
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	2/1183	10/18639	0.2	3.15114116652578	0.129124691093543	0.476740389484107
GO:0010851	cyclase regulator activity	3/1183	20/18639	0.15	2.36335587489434	0.130178425986984	0.476740389484107
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	3/1183	20/18639	0.15	2.36335587489434	0.130178425986984	0.476740389484107
GO:0030742	GTP-dependent protein binding	3/1183	20/18639	0.15	2.36335587489434	0.130178425986984	0.476740389484107
GO:0016500	protein-hormone receptor activity	7/1183	67/18639	0.104477611940299	1.6461185198269	0.131418263990531	0.479676663565439
GO:0005179	hormone activity	12/1183	132/18639	0.0909090909090909	1.43233689387536	0.133197095017967	0.484554216095264
GO:0048306	calcium-dependent protein binding	8/1183	80/18639	0.1	1.57557058326289	0.134255163547804	0.485576140048068
GO:0016829	lyase activity	17/1183	200/18639	0.085	1.33923499577346	0.134798459480745	0.485576140048068
GO:0008200	ion channel inhibitor activity	5/1183	43/18639	0.116279069767442	1.83205881774755	0.134808353036176	0.485576140048068
GO:0099106	ion channel regulator activity	14/1183	160/18639	0.0875	1.37862426035503	0.138967413587218	0.498915796321322
GO:0030971	receptor tyrosine kinase binding	8/1183	81/18639	0.0987654320987654	1.55611909458063	0.141228135280299	0.503769655763315
GO:0019888	protein phosphatase regulator activity	10/1183	107/18639	0.0934579439252336	1.47249587220831	0.141378064252166	0.503769655763315
GO:0046943	carboxylic acid transmembrane transporter activity	16/1183	188/18639	0.0851063829787234	1.34091113469182	0.142367936609436	0.503769655763315
GO:0120015	sterol transfer activity	4/1183	32/18639	0.125	1.96946322907861	0.142368706562048	0.503769655763315
GO:0019212	phosphatase inhibitor activity	6/1183	56/18639	0.107142857142857	1.68811133921024	0.142801748440395	0.503769655763315
GO:0004866	endopeptidase inhibitor activity	14/1183	161/18639	0.0869565217391304	1.37006137675034	0.143878204123067	0.503769655763315
GO:0051087	protein-folding chaperone binding	12/1183	134/18639	0.0895522388059701	1.4109587312802	0.143897454900914	0.503769655763315
GO:0016248	channel inhibitor activity	5/1183	44/18639	0.113636363636364	1.79042111734419	0.144658850967764	0.503769655763315
GO:0009975	cyclase activity	3/1183	21/18639	0.142857142857143	2.25081511894699	0.145100293685988	0.503769655763315
GO:0005342	organic acid transmembrane transporter activity	16/1183	189/18639	0.0846560846560847	1.3338163667834	0.146948003602844	0.503769655763315
GO:0043177	organic acid binding	16/1183	189/18639	0.0846560846560847	1.3338163667834	0.146948003602844	0.503769655763315
GO:0004954	prostanoid receptor activity	2/1183	11/18639	0.181818181818182	2.86467378775071	0.151452293159961	0.503769655763315
GO:0005114	type II transforming growth factor beta receptor binding	2/1183	11/18639	0.181818181818182	2.86467378775071	0.151452293159961	0.503769655763315
GO:0005225	volume-sensitive anion channel activity	2/1183	11/18639	0.181818181818182	2.86467378775071	0.151452293159961	0.503769655763315
GO:0008271	secondary active sulfate transmembrane transporter activity	2/1183	11/18639	0.181818181818182	2.86467378775071	0.151452293159961	0.503769655763315
GO:0008503	benzodiazepine receptor activity	2/1183	11/18639	0.181818181818182	2.86467378775071	0.151452293159961	0.503769655763315
GO:0015217	ADP transmembrane transporter activity	2/1183	11/18639	0.181818181818182	2.86467378775071	0.151452293159961	0.503769655763315
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	2/1183	11/18639	0.181818181818182	2.86467378775071	0.151452293159961	0.503769655763315
GO:0032050	clathrin heavy chain binding	2/1183	11/18639	0.181818181818182	2.86467378775071	0.151452293159961	0.503769655763315
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	2/1183	11/18639	0.181818181818182	2.86467378775071	0.151452293159961	0.503769655763315
GO:0050998	nitric-oxide synthase binding	2/1183	11/18639	0.181818181818182	2.86467378775071	0.151452293159961	0.503769655763315
GO:0070697	activin receptor binding	2/1183	11/18639	0.181818181818182	2.86467378775071	0.151452293159961	0.503769655763315
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	2/1183	11/18639	0.181818181818182	2.86467378775071	0.151452293159961	0.503769655763315
GO:0019902	phosphatase binding	16/1183	190/18639	0.0842105263157895	1.32679628064243	0.151608231398718	0.503769655763315
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	11/1183	122/18639	0.0901639344262295	1.42059642753212	0.151820992147848	0.503769655763315
GO:0042605	peptide antigen binding	5/1183	45/18639	0.111111111111111	1.75063398140321	0.154807962810836	0.510586503848993
GO:0141110	transporter inhibitor activity	5/1183	45/18639	0.111111111111111	1.75063398140321	0.154807962810836	0.510586503848993
GO:0005216	monoatomic ion channel activity	34/1183	448/18639	0.0758928571428571	1.19574553194059	0.159844527015651	0.525614886132546
GO:0005319	lipid transporter activity	15/1183	178/18639	0.0842696629213483	1.32772801960356	0.160378529226863	0.525791884740764
GO:0070888	E-box binding	6/1183	59/18639	0.101694915254237	1.60227516941989	0.169930507367449	0.553657775141701
GO:0070851	growth factor receptor binding	12/1183	139/18639	0.0863309352517986	1.36020482008307	0.172559130172281	0.553657775141701
GO:0005095	GTPase inhibitor activity	2/1183	12/18639	0.166666666666667	2.62595097210482	0.174455548505573	0.553657775141701
GO:0008179	adenylate cyclase binding	2/1183	12/18639	0.166666666666667	2.62595097210482	0.174455548505573	0.553657775141701
GO:0034452	dynactin binding	2/1183	12/18639	0.166666666666667	2.62595097210482	0.174455548505573	0.553657775141701
GO:0035259	nuclear glucocorticoid receptor binding	2/1183	12/18639	0.166666666666667	2.62595097210482	0.174455548505573	0.553657775141701
GO:0045295	gamma-catenin binding	2/1183	12/18639	0.166666666666667	2.62595097210482	0.174455548505573	0.553657775141701
GO:0070679	inositol 1,4,5 trisphosphate binding	2/1183	12/18639	0.166666666666667	2.62595097210482	0.174455548505573	0.553657775141701
GO:0141221	histone deacetylase activity, hydrolytic mechanism	2/1183	12/18639	0.166666666666667	2.62595097210482	0.174455548505573	0.553657775141701
GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	2/1183	12/18639	0.166666666666667	2.62595097210482	0.174455548505573	0.553657775141701
GO:1990459	transferrin receptor binding	2/1183	12/18639	0.166666666666667	2.62595097210482	0.174455548505573	0.553657775141701
GO:0016874	ligase activity	14/1183	167/18639	0.0838323353293413	1.32083761471141	0.175265909469672	0.553657775141701
GO:0017134	fibroblast growth factor binding	3/1183	23/18639	0.130434782608696	2.05509206512551	0.176462615090825	0.553657775141701
GO:0043274	phospholipase binding	3/1183	23/18639	0.130434782608696	2.05509206512551	0.176462615090825	0.553657775141701
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	3/1183	23/18639	0.130434782608696	2.05509206512551	0.176462615090825	0.553657775141701
GO:0043015	gamma-tubulin binding	4/1183	35/18639	0.114285714285714	1.80065209515759	0.179491843197036	0.56155305228787
GO:0140693	molecular condensate scaffold activity	5/1183	48/18639	0.104166666666667	1.64121935756551	0.186902377565102	0.583071519754378
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	6/1183	61/18639	0.0983606557377049	1.54974155730776	0.189115483557154	0.588299586633759
GO:0005261	monoatomic cation channel activity	26/1183	341/18639	0.0762463343108504	1.20131481421804	0.191240710917622	0.592987051269735
GO:0015295	solute:proton symporter activity	3/1183	24/18639	0.125	1.96946322907861	0.192788484248425	0.592987051269735
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	3/1183	24/18639	0.125	1.96946322907861	0.192788484248425	0.592987051269735
GO:0030552	cAMP binding	3/1183	24/18639	0.125	1.96946322907861	0.192788484248425	0.592987051269735
GO:0035591	signaling adaptor activity	11/1183	129/18639	0.0852713178294574	1.34350979968153	0.196189708970343	0.593770394923554
GO:0005172	vascular endothelial growth factor receptor binding	2/1183	13/18639	0.153846153846154	2.42395474348137	0.197958955159232	0.593770394923554
GO:0008035	high-density lipoprotein particle binding	2/1183	13/18639	0.153846153846154	2.42395474348137	0.197958955159232	0.593770394923554
GO:0031432	titin binding	2/1183	13/18639	0.153846153846154	2.42395474348137	0.197958955159232	0.593770394923554
GO:0031994	insulin-like growth factor I binding	2/1183	13/18639	0.153846153846154	2.42395474348137	0.197958955159232	0.593770394923554
GO:0039706	co-receptor binding	2/1183	13/18639	0.153846153846154	2.42395474348137	0.197958955159232	0.593770394923554
GO:0071837	HMG box domain binding	2/1183	13/18639	0.153846153846154	2.42395474348137	0.197958955159232	0.593770394923554
GO:0016763	pentosyltransferase activity	5/1183	49/18639	0.102040816326531	1.60772508496213	0.198098717546241	0.593770394923554
GO:0035254	glutamate receptor binding	5/1183	49/18639	0.102040816326531	1.60772508496213	0.198098717546241	0.593770394923554
GO:0015171	amino acid transmembrane transporter activity	9/1183	102/18639	0.0882352941176471	1.39020933817314	0.198775783912587	0.593770394923554
GO:0015179	L-amino acid transmembrane transporter activity	6/1183	62/18639	0.0967741935483871	1.52474572573828	0.199007977111365	0.593770394923554
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	8/1183	89/18639	0.0898876404494382	1.41624322091046	0.202989696913358	0.602367799783542
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	8/1183	89/18639	0.0898876404494382	1.41624322091046	0.202989696913358	0.602367799783542
GO:0030551	cyclic nucleotide binding	4/1183	37/18639	0.108108108108108	1.7033195494734	0.205839024281905	0.60917224753699
GO:0017022	myosin binding	7/1183	76/18639	0.0921052631578947	1.45118343195266	0.206592501236532	0.609754147854454
GO:0031406	carboxylic acid binding	15/1183	187/18639	0.0802139037433155	1.26382667106649	0.208946918614039	0.610164693840246
GO:0004709	MAP kinase kinase kinase activity	3/1183	25/18639	0.12	1.89068469991547	0.209469549592371	0.610164693840246
GO:0005537	D-mannose binding	3/1183	25/18639	0.12	1.89068469991547	0.209469549592371	0.610164693840246
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	3/1183	25/18639	0.12	1.89068469991547	0.209469549592371	0.610164693840246
GO:0032813	tumor necrosis factor receptor superfamily binding	5/1183	50/18639	0.1	1.57557058326289	0.20951773962003	0.610164693840246
GO:0140793	histone H2AXY142 phosphatase activity	8/1183	90/18639	0.0888888888888889	1.40050718512257	0.21138353684791	0.613965445221384
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	11/1183	132/18639	0.0833333333333333	1.31297548605241	0.216796156602077	0.618010572281979
GO:0005501	retinoid binding	4/1183	38/18639	0.105263157894737	1.65849535080304	0.219410960272	0.618010572281979
GO:0019840	isoprenoid binding	4/1183	38/18639	0.105263157894737	1.65849535080304	0.219410960272	0.618010572281979
GO:0042887	amide transmembrane transporter activity	4/1183	38/18639	0.105263157894737	1.65849535080304	0.219410960272	0.618010572281979
GO:0016830	carbon-carbon lyase activity	5/1183	51/18639	0.0980392156862745	1.5446770424146	0.221143162867459	0.618010572281979
GO:0030544	Hsp70 protein binding	5/1183	51/18639	0.0980392156862745	1.5446770424146	0.221143162867459	0.618010572281979
GO:0004705	JUN kinase activity	2/1183	14/18639	0.142857142857143	2.25081511894699	0.221806534161478	0.618010572281979
GO:0005313	L-glutamate transmembrane transporter activity	2/1183	14/18639	0.142857142857143	2.25081511894699	0.221806534161478	0.618010572281979
GO:0005347	ATP transmembrane transporter activity	2/1183	14/18639	0.142857142857143	2.25081511894699	0.221806534161478	0.618010572281979
GO:0016530	metallochaperone activity	2/1183	14/18639	0.142857142857143	2.25081511894699	0.221806534161478	0.618010572281979
GO:0019992	diacylglycerol binding	2/1183	14/18639	0.142857142857143	2.25081511894699	0.221806534161478	0.618010572281979
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	2/1183	14/18639	0.142857142857143	2.25081511894699	0.221806534161478	0.618010572281979
GO:0031404	chloride ion binding	2/1183	14/18639	0.142857142857143	2.25081511894699	0.221806534161478	0.618010572281979
GO:0042043	neurexin family protein binding	2/1183	14/18639	0.142857142857143	2.25081511894699	0.221806534161478	0.618010572281979
GO:0061665	SUMO ligase activity	2/1183	14/18639	0.142857142857143	2.25081511894699	0.221806534161478	0.618010572281979
GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	2/1183	14/18639	0.142857142857143	2.25081511894699	0.221806534161478	0.618010572281979
GO:0001637	G protein-coupled chemoattractant receptor activity	3/1183	26/18639	0.115384615384615	1.81796605761103	0.226451723669291	0.621465256686399
GO:0004950	chemokine receptor activity	3/1183	26/18639	0.115384615384615	1.81796605761103	0.226451723669291	0.621465256686399
GO:0015216	purine nucleotide transmembrane transporter activity	3/1183	26/18639	0.115384615384615	1.81796605761103	0.226451723669291	0.621465256686399
GO:0030247	polysaccharide binding	3/1183	26/18639	0.115384615384615	1.81796605761103	0.226451723669291	0.621465256686399
GO:0043548	phosphatidylinositol 3-kinase binding	3/1183	26/18639	0.115384615384615	1.81796605761103	0.226451723669291	0.621465256686399
GO:0070006	metalloaminopeptidase activity	3/1183	26/18639	0.115384615384615	1.81796605761103	0.226451723669291	0.621465256686399
GO:0030159	signaling receptor complex adaptor activity	5/1183	52/18639	0.0961538461538462	1.51497171467586	0.232958529399543	0.636826416014393
GO:0016776	phosphotransferase activity, phosphate group as acceptor	4/1183	39/18639	0.102564102564103	1.61596982898758	0.233212230887463	0.636826416014393
GO:0005516	calmodulin binding	16/1183	207/18639	0.0772946859903382	1.21783233488919	0.242126037017277	0.645603759122368
GO:0008266	poly(U) RNA binding	3/1183	27/18639	0.111111111111111	1.75063398140321	0.243682750052634	0.645603759122368
GO:0035255	ionotropic glutamate receptor binding	3/1183	27/18639	0.111111111111111	1.75063398140321	0.243682750052634	0.645603759122368
GO:0004864	protein phosphatase inhibitor activity	5/1183	53/18639	0.0943396226415094	1.48638734270084	0.244947277392952	0.645603759122368
GO:0016860	intramolecular oxidoreductase activity	5/1183	53/18639	0.0943396226415094	1.48638734270084	0.244947277392952	0.645603759122368
GO:0051018	protein kinase A binding	5/1183	53/18639	0.0943396226415094	1.48638734270084	0.244947277392952	0.645603759122368
GO:0004559	alpha-mannosidase activity	2/1183	15/18639	0.133333333333333	2.10076077768385	0.245860061693176	0.645603759122368
GO:0004953	icosanoid receptor activity	2/1183	15/18639	0.133333333333333	2.10076077768385	0.245860061693176	0.645603759122368
GO:0015116	sulfate transmembrane transporter activity	2/1183	15/18639	0.133333333333333	2.10076077768385	0.245860061693176	0.645603759122368
GO:0017081	chloride channel regulator activity	2/1183	15/18639	0.133333333333333	2.10076077768385	0.245860061693176	0.645603759122368
GO:0034483	heparan sulfate sulfotransferase activity	2/1183	15/18639	0.133333333333333	2.10076077768385	0.245860061693176	0.645603759122368
GO:0050780	dopamine receptor binding	2/1183	15/18639	0.133333333333333	2.10076077768385	0.245860061693176	0.645603759122368
GO:0120283	protein serine/threonine kinase binding	2/1183	15/18639	0.133333333333333	2.10076077768385	0.245860061693176	0.645603759122368
GO:0140776	protein-containing complex destabilizing activity	2/1183	15/18639	0.133333333333333	2.10076077768385	0.245860061693176	0.645603759122368
GO:0141050	histone H3K deacetylase activity	2/1183	15/18639	0.133333333333333	2.10076077768385	0.245860061693176	0.645603759122368
GO:0141051	histone H4K deacetylase activity	2/1183	15/18639	0.133333333333333	2.10076077768385	0.245860061693176	0.645603759122368
GO:0005496	steroid binding	9/1183	108/18639	0.0833333333333333	1.31297548605241	0.2467994204711	0.646520012956589
GO:0004620	phospholipase activity	9/1183	109/18639	0.0825688073394495	1.30092983939138	0.255167447805761	0.66684571681935
GO:0015485	cholesterol binding	5/1183	54/18639	0.0925925925925926	1.45886165116934	0.257092810050483	0.668685574834392
GO:0051287	NAD binding	5/1183	54/18639	0.0925925925925926	1.45886165116934	0.257092810050483	0.668685574834392
GO:0019789	SUMO transferase activity	3/1183	28/18639	0.107142857142857	1.68811133921024	0.261112416508018	0.67315316090691
GO:0045499	chemorepellent activity	3/1183	28/18639	0.107142857142857	1.68811133921024	0.261112416508018	0.67315316090691
GO:0017080	sodium channel regulator activity	4/1183	41/18639	0.0975609756097561	1.5371420324516	0.261395292304539	0.67315316090691
GO:0042287	MHC protein binding	4/1183	41/18639	0.0975609756097561	1.5371420324516	0.261395292304539	0.67315316090691
GO:0032934	sterol binding	6/1183	68/18639	0.0882352941176471	1.39020933817314	0.261884243421319	0.67315316090691
GO:0008514	organic anion transmembrane transporter activity	20/1183	269/18639	0.0743494423791822	1.17142794294639	0.263153875540499	0.674832537978564
GO:0030295	protein kinase activator activity	11/1183	139/18639	0.079136690647482	1.24685441840948	0.268002445835608	0.67964874508241
GO:0004707	MAP kinase activity	2/1183	16/18639	0.125	1.96946322907861	0.269997446676574	0.67964874508241
GO:0004708	MAP kinase kinase activity	2/1183	16/18639	0.125	1.96946322907861	0.269997446676574	0.67964874508241
GO:0005024	transforming growth factor beta receptor activity	2/1183	16/18639	0.125	1.96946322907861	0.269997446676574	0.67964874508241
GO:0008142	oxysterol binding	2/1183	16/18639	0.125	1.96946322907861	0.269997446676574	0.67964874508241
GO:0015562	efflux transmembrane transporter activity	2/1183	16/18639	0.125	1.96946322907861	0.269997446676574	0.67964874508241
GO:0019841	retinol binding	2/1183	16/18639	0.125	1.96946322907861	0.269997446676574	0.67964874508241
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	2/1183	16/18639	0.125	1.96946322907861	0.269997446676574	0.67964874508241
GO:0019894	kinesin binding	4/1183	42/18639	0.0952380952380952	1.50054341263132	0.275724275514761	0.692472664423539
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	3/1183	29/18639	0.103448275862069	1.6299006033754	0.278692719404871	0.698326150453852
GO:0004725	protein tyrosine phosphatase activity	8/1183	98/18639	0.0816326530612245	1.28618006796971	0.282744207963537	0.706860519908843
GO:0008028	monocarboxylic acid transmembrane transporter activity	6/1183	70/18639	0.0857142857142857	1.35048907136819	0.283914739132146	0.708170021297721
GO:0048156	tau protein binding	4/1183	43/18639	0.0930232558139535	1.46564705419804	0.290177190640769	0.71886564858938
GO:0004550	nucleoside diphosphate kinase activity	2/1183	17/18639	0.117647058823529	1.85361245089752	0.294111242527892	0.71886564858938
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	2/1183	17/18639	0.117647058823529	1.85361245089752	0.294111242527892	0.71886564858938
GO:0015347	sodium-independent organic anion transmembrane transporter activity	2/1183	17/18639	0.117647058823529	1.85361245089752	0.294111242527892	0.71886564858938
GO:0016018	cyclosporin A binding	2/1183	17/18639	0.117647058823529	1.85361245089752	0.294111242527892	0.71886564858938
GO:0016805	dipeptidase activity	2/1183	17/18639	0.117647058823529	1.85361245089752	0.294111242527892	0.71886564858938
GO:0038191	neuropilin binding	2/1183	17/18639	0.117647058823529	1.85361245089752	0.294111242527892	0.71886564858938
GO:0046965	nuclear retinoid X receptor binding	2/1183	17/18639	0.117647058823529	1.85361245089752	0.294111242527892	0.71886564858938
GO:0070492	oligosaccharide binding	2/1183	17/18639	0.117647058823529	1.85361245089752	0.294111242527892	0.71886564858938
GO:0001965	G-protein alpha-subunit binding	3/1183	30/18639	0.1	1.57557058326289	0.296377985600409	0.719587348630704
GO:0008187	poly-pyrimidine tract binding	3/1183	30/18639	0.1	1.57557058326289	0.296377985600409	0.719587348630704
GO:0015215	nucleotide transmembrane transporter activity	3/1183	30/18639	0.1	1.57557058326289	0.296377985600409	0.719587348630704
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	7/1183	86/18639	0.0813953488372093	1.28244117242328	0.30431958622294	0.73335886141942
GO:0001223	transcription coactivator binding	4/1183	44/18639	0.0909090909090909	1.43233689387536	0.30472902460807	0.73335886141942
GO:0019205	nucleobase-containing compound kinase activity	4/1183	44/18639	0.0909090909090909	1.43233689387536	0.30472902460807	0.73335886141942
GO:0030547	signaling receptor inhibitor activity	4/1183	44/18639	0.0909090909090909	1.43233689387536	0.30472902460807	0.73335886141942
GO:0001221	transcription coregulator binding	9/1183	115/18639	0.0782608695652174	1.23305523907531	0.307095301560805	0.737432796511142
GO:0005184	neuropeptide hormone activity	3/1183	31/18639	0.0967741935483871	1.52474572573828	0.314124957372249	0.748134913220788
GO:0070273	phosphatidylinositol-4-phosphate binding	3/1183	31/18639	0.0967741935483871	1.52474572573828	0.314124957372249	0.748134913220788
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	2/1183	18/18639	0.111111111111111	1.75063398140321	0.318107282589811	0.748134913220788
GO:0004970	glutamate-gated receptor activity	2/1183	18/18639	0.111111111111111	1.75063398140321	0.318107282589811	0.748134913220788
GO:0017075	syntaxin-1 binding	2/1183	18/18639	0.111111111111111	1.75063398140321	0.318107282589811	0.748134913220788
GO:0031690	adrenergic receptor binding	2/1183	18/18639	0.111111111111111	1.75063398140321	0.318107282589811	0.748134913220788
GO:0050811	GABA receptor binding	2/1183	18/18639	0.111111111111111	1.75063398140321	0.318107282589811	0.748134913220788
GO:0070064	proline-rich region binding	2/1183	18/18639	0.111111111111111	1.75063398140321	0.318107282589811	0.748134913220788
GO:0046982	protein heterodimerization activity	26/1183	369/18639	0.0704607046070461	1.11015813454838	0.318285252990857	0.748134913220788
GO:0046915	transition metal ion transmembrane transporter activity	4/1183	45/18639	0.0888888888888889	1.40050718512257	0.319355469661459	0.748134913220788
GO:0070063	RNA polymerase binding	5/1183	59/18639	0.0847457627118644	1.33522930784991	0.31959671290588	0.748134913220788
GO:0005262	calcium channel activity	10/1183	131/18639	0.0763358778625954	1.20272563607854	0.319750812225871	0.748134913220788
GO:0008238	exopeptidase activity	8/1183	102/18639	0.0784313725490196	1.23574163393168	0.320562701193082	0.74843530449131
GO:0048029	monosaccharide binding	6/1183	74/18639	0.0810810810810811	1.27748966210505	0.329035649708076	0.76510034883973
GO:0015085	calcium ion transmembrane transporter activity	11/1183	147/18639	0.0748299319727891	1.1789983956389	0.330633821674453	0.76510034883973
GO:0022884	macromolecule transmembrane transporter activity	3/1183	32/18639	0.09375	1.47709742180896	0.331892845387098	0.76510034883973
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	3/1183	32/18639	0.09375	1.47709742180896	0.331892845387098	0.76510034883973
GO:0070717	poly-purine tract binding	3/1183	32/18639	0.09375	1.47709742180896	0.331892845387098	0.76510034883973
GO:0160041	neuropeptide activity	3/1183	32/18639	0.09375	1.47709742180896	0.331892845387098	0.76510034883973
GO:0140996	histone H3 kinase activity	25/1183	357/18639	0.0700280112044818	1.10334074458186	0.333900676606027	0.768111850595796
GO:0019209	kinase activator activity	11/1183	148/18639	0.0743243243243243	1.17103219026296	0.338682334955955	0.771926299726785
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	2/1183	19/18639	0.105263157894737	1.65849535080304	0.341903429559352	0.771926299726785
GO:0005346	purine ribonucleotide transmembrane transporter activity	2/1183	19/18639	0.105263157894737	1.65849535080304	0.341903429559352	0.771926299726785
GO:0005520	insulin-like growth factor binding	2/1183	19/18639	0.105263157894737	1.65849535080304	0.341903429559352	0.771926299726785
GO:0008301	DNA binding, bending	2/1183	19/18639	0.105263157894737	1.65849535080304	0.341903429559352	0.771926299726785
GO:0016918	retinal binding	2/1183	19/18639	0.105263157894737	1.65849535080304	0.341903429559352	0.771926299726785
GO:0042834	peptidoglycan binding	2/1183	19/18639	0.105263157894737	1.65849535080304	0.341903429559352	0.771926299726785
GO:0050145	nucleoside monophosphate kinase activity	2/1183	19/18639	0.105263157894737	1.65849535080304	0.341903429559352	0.771926299726785
GO:0070003	threonine-type peptidase activity	2/1183	19/18639	0.105263157894737	1.65849535080304	0.341903429559352	0.771926299726785
GO:0008509	monoatomic anion transmembrane transporter activity	11/1183	149/18639	0.0738255033557047	1.16317291381824	0.346766975358888	0.781295962999964
GO:0035173	histone kinase activity	25/1183	360/18639	0.0694444444444444	1.09414623837701	0.34943373764453	0.785687767393758
GO:0008013	beta-catenin binding	8/1183	106/18639	0.0754716981132075	1.18910987416067	0.359241653160339	0.806085266824942
GO:0042578	phosphoric ester hydrolase activity	25/1183	363/18639	0.068870523415978	1.08510370748133	0.365132924942732	0.813301078866115
GO:0000339	RNA cap binding	2/1183	20/18639	0.1	1.57557058326289	0.365428429956282	0.813301078866115
GO:0016004	phospholipase activator activity	2/1183	20/18639	0.1	1.57557058326289	0.365428429956282	0.813301078866115
GO:0140939	histone H4 methyltransferase activity	2/1183	20/18639	0.1	1.57557058326289	0.365428429956282	0.813301078866115
GO:0016831	carboxy-lyase activity	3/1183	34/18639	0.0882352941176471	1.39020933817314	0.367340683972955	0.814247062652603
GO:0030332	cyclin binding	3/1183	34/18639	0.0882352941176471	1.39020933817314	0.367340683972955	0.814247062652603
GO:1901682	sulfur compound transmembrane transporter activity	5/1183	63/18639	0.0793650793650794	1.25045284385944	0.370778224337669	0.820206375049995
GO:0060590	ATPase regulator activity	4/1183	49/18639	0.0816326530612245	1.28618006796971	0.378149286122775	0.834825540936369
GO:0005154	epidermal growth factor receptor binding	3/1183	35/18639	0.0857142857142857	1.35048907136819	0.384951512795698	0.846003673084899
GO:0016229	steroid dehydrogenase activity	3/1183	35/18639	0.0857142857142857	1.35048907136819	0.384951512795698	0.846003673084899
GO:0008373	sialyltransferase activity	2/1183	21/18639	0.0952380952380952	1.50054341263132	0.388620865353155	0.846003673084899
GO:0010314	phosphatidylinositol-5-phosphate binding	2/1183	21/18639	0.0952380952380952	1.50054341263132	0.388620865353155	0.846003673084899
GO:0015125	bile acid transmembrane transporter activity	2/1183	21/18639	0.0952380952380952	1.50054341263132	0.388620865353155	0.846003673084899
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	2/1183	21/18639	0.0952380952380952	1.50054341263132	0.388620865353155	0.846003673084899
GO:0051428	peptide hormone receptor binding	2/1183	21/18639	0.0952380952380952	1.50054341263132	0.388620865353155	0.846003673084899
GO:0001216	DNA-binding transcription activator activity	33/1183	491/18639	0.0672097759674134	1.05893745921946	0.391698677249733	0.851012007119955
GO:0120013	lipid transfer activity	5/1183	65/18639	0.0769230769230769	1.21197737174069	0.396433112600887	0.859592590689052
GO:0004867	serine-type endopeptidase inhibitor activity	7/1183	95/18639	0.0736842105263158	1.16094674556213	0.398531660677173	0.860345293482206
GO:0004869	cysteine-type endopeptidase inhibitor activity	3/1183	36/18639	0.0833333333333333	1.31297548605241	0.402444961336027	0.860345293482206
GO:0044390	ubiquitin-like protein conjugating enzyme binding	3/1183	36/18639	0.0833333333333333	1.31297548605241	0.402444961336027	0.860345293482206
GO:0045505	dynein intermediate chain binding	3/1183	36/18639	0.0833333333333333	1.31297548605241	0.402444961336027	0.860345293482206
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	3/1183	36/18639	0.0833333333333333	1.31297548605241	0.402444961336027	0.860345293482206
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	3/1183	36/18639	0.0833333333333333	1.31297548605241	0.402444961336027	0.860345293482206
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	3/1183	36/18639	0.0833333333333333	1.31297548605241	0.402444961336027	0.860345293482206
GO:0001217	DNA-binding transcription repressor activity	19/1183	278/18639	0.0683453237410072	1.0768288158991	0.403065877220431	0.860345293482206
GO:1902936	phosphatidylinositol bisphosphate binding	8/1183	111/18639	0.0720720720720721	1.1355463663156	0.408162783862088	0.868042140698509
GO:0004896	cytokine receptor activity	7/1183	96/18639	0.0729166666666667	1.14885355029586	0.409089931581951	0.868042140698509
GO:0008235	metalloexopeptidase activity	5/1183	66/18639	0.0757575757575758	1.19361407822946	0.409228536888617	0.868042140698509
GO:0004407	histone deacetylase activity	2/1183	22/18639	0.0909090909090909	1.43233689387536	0.411428192714636	0.868042140698509
GO:0008970	phospholipase A1 activity	2/1183	22/18639	0.0909090909090909	1.43233689387536	0.411428192714636	0.868042140698509
GO:0033558	protein lysine deacetylase activity	2/1183	22/18639	0.0909090909090909	1.43233689387536	0.411428192714636	0.868042140698509
GO:0042805	actinin binding	3/1183	37/18639	0.0810810810810811	1.27748966210505	0.419792544017273	0.88398622249791
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	5/1183	67/18639	0.0746268656716418	1.1757989427335	0.42198555910263	0.886307432946946
GO:0004175	endopeptidase activity	27/1183	405/18639	0.0666666666666667	1.05038038884193	0.423985228726118	0.886307432946946
GO:0008170	N-methyltransferase activity	7/1183	98/18639	0.0714285714285714	1.12540755947349	0.430168118868267	0.886307432946946
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	32/1183	484/18639	0.0661157024793388	1.04169955918208	0.431324590381742	0.886307432946946
GO:0030165	PDZ domain binding	6/1183	83/18639	0.072289156626506	1.13896668669607	0.432521729896644	0.886307432946946
GO:0000295	adenine nucleotide transmembrane transporter activity	2/1183	23/18639	0.0869565217391304	1.37006137675034	0.433805866774045	0.886307432946946
GO:0005283	amino acid:sodium symporter activity	2/1183	23/18639	0.0869565217391304	1.37006137675034	0.433805866774045	0.886307432946946
GO:0016493	C-C chemokine receptor activity	2/1183	23/18639	0.0869565217391304	1.37006137675034	0.433805866774045	0.886307432946946
GO:0030145	manganese ion binding	5/1183	68/18639	0.0735294117647059	1.15850778181095	0.434692012728131	0.886307432946946
GO:0008146	sulfotransferase activity	4/1183	53/18639	0.0754716981132075	1.18910987416067	0.436411967785549	0.886307432946946
GO:0140296	general transcription initiation factor binding	4/1183	53/18639	0.0754716981132075	1.18910987416067	0.436411967785549	0.886307432946946
GO:0016298	lipase activity	9/1183	130/18639	0.0692307692307692	1.09077963456662	0.443649323629775	0.886307432946946
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	4/1183	54/18639	0.0740740740740741	1.16708932093547	0.450757500404354	0.886307432946946
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	3/1183	39/18639	0.0769230769230769	1.21197737174069	0.453947764792532	0.886307432946946
GO:0001091	RNA polymerase II general transcription initiation factor binding	2/1183	24/18639	0.0833333333333333	1.31297548605241	0.455716537912738	0.886307432946946
GO:0005315	phosphate transmembrane transporter activity	2/1183	24/18639	0.0833333333333333	1.31297548605241	0.455716537912738	0.886307432946946
GO:0019957	C-C chemokine binding	2/1183	24/18639	0.0833333333333333	1.31297548605241	0.455716537912738	0.886307432946946
GO:0030215	semaphorin receptor binding	2/1183	24/18639	0.0833333333333333	1.31297548605241	0.455716537912738	0.886307432946946
GO:0060229	lipase activator activity	2/1183	24/18639	0.0833333333333333	1.31297548605241	0.455716537912738	0.886307432946946
GO:0070300	phosphatidic acid binding	2/1183	24/18639	0.0833333333333333	1.31297548605241	0.455716537912738	0.886307432946946
GO:0098632	cell-cell adhesion mediator activity	4/1183	55/18639	0.0727272727272727	1.14586951510028	0.464983299621726	0.886307432946946
GO:0004177	aminopeptidase activity	3/1183	40/18639	0.075	1.18167793744717	0.470709809259081	0.886307432946946
GO:0015645	fatty acid ligase activity	2/1183	25/18639	0.08	1.26045646661031	0.477129319505814	0.886307432946946
GO:0015662	P-type ion transporter activity	2/1183	25/18639	0.08	1.26045646661031	0.477129319505814	0.886307432946946
GO:0042974	nuclear retinoic acid receptor binding	2/1183	25/18639	0.08	1.26045646661031	0.477129319505814	0.886307432946946
GO:0120515	fatty acid-CoA ligase activity	2/1183	25/18639	0.08	1.26045646661031	0.477129319505814	0.886307432946946
GO:0140358	P-type transmembrane transporter activity	2/1183	25/18639	0.08	1.26045646661031	0.477129319505814	0.886307432946946
GO:0015103	inorganic anion transmembrane transporter activity	11/1183	165/18639	0.0666666666666667	1.05038038884193	0.477985403681297	0.886307432946946
GO:0019001	guanyl nucleotide binding	26/1183	400/18639	0.065	1.02412087912088	0.479156445341312	0.886307432946946
GO:0032561	guanyl ribonucleotide binding	26/1183	400/18639	0.065	1.02412087912088	0.479156445341312	0.886307432946946
GO:0001094	TFIID-class transcription factor complex binding	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0003796	lysozyme activity	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0004090	carbonyl reductase (NADPH) activity	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0005345	purine nucleobase transmembrane transporter activity	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0005528	FK506 binding	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0008140	cAMP response element binding protein binding	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0008190	eukaryotic initiation factor 4E binding	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0008519	ammonium channel activity	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0008641	ubiquitin-like modifier activating enzyme activity	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0015279	store-operated calcium channel activity	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0015658	branched-chain amino acid transmembrane transporter activity	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0015924	mannosyl-oligosaccharide mannosidase activity	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0016303	1-phosphatidylinositol-3-kinase activity	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0019531	oxalate transmembrane transporter activity	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0019911	structural constituent of myelin sheath	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0030957	Tat protein binding	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0032052	bile acid binding	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0032356	oxidized DNA binding	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0033204	ribonuclease P RNA binding	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0035256	G protein-coupled glutamate receptor binding	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0043121	neurotrophin binding	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0043208	glycosphingolipid binding	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0043295	glutathione binding	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0047429	nucleoside triphosphate diphosphatase activity	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0050815	phosphoserine residue binding	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0051880	G-quadruplex DNA binding	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0140999	histone H3K4 trimethyltransferase activity	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0141109	transporter activator activity	1/1183	10/18639	0.1	1.57557058326289	0.481020544642861	0.886307432946946
GO:0005253	monoatomic anion channel activity	7/1183	103/18639	0.0679611650485437	1.0707761245476	0.482314429936734	0.886307432946946
GO:0015631	tubulin binding	25/1183	385/18639	0.0649350649350649	1.02309778133954	0.482770061829282	0.886307432946946
GO:0141003	histone H2AX kinase activity	23/1183	354/18639	0.0649717514124294	1.02367580268493	0.484842058974205	0.886307432946946
GO:0015175	neutral L-amino acid transmembrane transporter activity	3/1183	41/18639	0.0731707317073171	1.1528565243387	0.487234639544966	0.886307432946946
GO:0016877	ligase activity, forming carbon-sulfur bonds	3/1183	41/18639	0.0731707317073171	1.1528565243387	0.487234639544966	0.886307432946946
GO:0140318	protein transporter activity	3/1183	41/18639	0.0731707317073171	1.1528565243387	0.487234639544966	0.886307432946946
GO:0008066	glutamate receptor activity	2/1183	26/18639	0.0769230769230769	1.21197737174069	0.498019119158857	0.886307432946946
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	2/1183	26/18639	0.0769230769230769	1.21197737174069	0.498019119158857	0.886307432946946
GO:0008143	poly(A) binding	2/1183	26/18639	0.0769230769230769	1.21197737174069	0.498019119158857	0.886307432946946
GO:0008198	ferrous iron binding	2/1183	26/18639	0.0769230769230769	1.21197737174069	0.498019119158857	0.886307432946946
GO:0034237	protein kinase A regulatory subunit binding	2/1183	26/18639	0.0769230769230769	1.21197737174069	0.498019119158857	0.886307432946946
GO:0050681	nuclear androgen receptor binding	2/1183	26/18639	0.0769230769230769	1.21197737174069	0.498019119158857	0.886307432946946
GO:0097602	cullin family protein binding	2/1183	26/18639	0.0769230769230769	1.21197737174069	0.498019119158857	0.886307432946946
GO:0120014	phospholipid transfer activity	2/1183	26/18639	0.0769230769230769	1.21197737174069	0.498019119158857	0.886307432946946
GO:0140789	histone phosphatase activity	9/1183	136/18639	0.0661764705882353	1.04265700362985	0.498057148027762	0.886307432946946
GO:0016859	cis-trans isomerase activity	3/1183	42/18639	0.0714285714285714	1.12540755947349	0.503504667547289	0.886307432946946
GO:0035198	miRNA binding	3/1183	42/18639	0.0714285714285714	1.12540755947349	0.503504667547289	0.886307432946946
GO:0008237	metallopeptidase activity	12/1183	184/18639	0.0652173913043478	1.02754603256275	0.504136233001386	0.886307432946946
GO:0015108	chloride transmembrane transporter activity	8/1183	121/18639	0.0661157024793388	1.04169955918208	0.505039314633428	0.886307432946946
GO:0051082	unfolded protein binding	8/1183	121/18639	0.0661157024793388	1.04169955918208	0.505039314633428	0.886307432946946
GO:0061980	regulatory RNA binding	4/1183	58/18639	0.0689655172413793	1.08660040225027	0.506805875279895	0.886307432946946
GO:0016922	nuclear receptor binding	9/1183	137/18639	0.0656934306569343	1.03504636856686	0.506994606351782	0.886307432946946
GO:0000099	sulfur amino acid transmembrane transporter activity	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:0003953	NAD+ nucleosidase activity	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:0004016	adenylate cyclase activity	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:0004117	calmodulin-activated dual specificity 3',5'-cyclic-GMP, 3',5'-cyclic-AMP phosphodiesterase activity	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:0005536	D-glucose binding	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:0008172	S-methyltransferase activity	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:0008199	ferric iron binding	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:0008526	phosphatidylinositol transfer activity	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:0015173	aromatic amino acid transmembrane transporter activity	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:0015205	nucleobase transmembrane transporter activity	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:0019215	intermediate filament binding	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:0035252	UDP-xylosyltransferase activity	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:0042285	xylosyltransferase activity	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:0047676	arachidonate-CoA ligase activity	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:0048101	calmodulin-activated 3',5'-cyclic-GMP phosphodiesterase activity	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:0048185	activin binding	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:0070990	snRNP binding	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:0098973	structural constituent of postsynaptic actin cytoskeleton	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:0140537	transcription regulator activator activity	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:1900750	oligopeptide binding	1/1183	11/18639	0.0909090909090909	1.43233689387536	0.513977369791151	0.886307432946946
GO:0001671	ATPase activator activity	2/1183	27/18639	0.0740740740740741	1.16708932093547	0.518366028687355	0.886891877207271
GO:0005104	fibroblast growth factor receptor binding	2/1183	27/18639	0.0740740740740741	1.16708932093547	0.518366028687355	0.886891877207271
GO:0008320	protein transmembrane transporter activity	2/1183	27/18639	0.0740740740740741	1.16708932093547	0.518366028687355	0.886891877207271
GO:0016405	CoA-ligase activity	2/1183	27/18639	0.0740740740740741	1.16708932093547	0.518366028687355	0.886891877207271
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	2/1183	27/18639	0.0740740740740741	1.16708932093547	0.518366028687355	0.886891877207271
GO:0005245	voltage-gated calcium channel activity	3/1183	43/18639	0.0697674418604651	1.09923529064853	0.519504228315278	0.887452620912995
GO:0015459	potassium channel regulator activity	4/1183	59/18639	0.0677966101694915	1.06818344627993	0.520421087088914	0.887634097137634
GO:0008234	cysteine-type peptidase activity	12/1183	187/18639	0.0641711229946524	1.01106133685319	0.527096545800437	0.891783369131964
GO:0003714	transcription corepressor activity	13/1183	204/18639	0.0637254901960784	1.00404007756949	0.535132608949995	0.891783369131964
GO:0046625	sphingolipid binding	2/1183	28/18639	0.0714285714285714	1.12540755947349	0.538154768085766	0.891783369131964
GO:0050698	proteoglycan sulfotransferase activity	2/1183	28/18639	0.0714285714285714	1.12540755947349	0.538154768085766	0.891783369131964
GO:0004032	aldose reductase (NADPH) activity	1/1183	12/18639	0.0833333333333333	1.31297548605241	0.544842989908022	0.891783369131964
GO:0004126	cytidine deaminase activity	1/1183	12/18639	0.0833333333333333	1.31297548605241	0.544842989908022	0.891783369131964
GO:0004300	enoyl-CoA hydratase activity	1/1183	12/18639	0.0833333333333333	1.31297548605241	0.544842989908022	0.891783369131964
GO:0004526	ribonuclease P activity	1/1183	12/18639	0.0833333333333333	1.31297548605241	0.544842989908022	0.891783369131964
GO:0005025	transforming growth factor beta receptor activity, type I	1/1183	12/18639	0.0833333333333333	1.31297548605241	0.544842989908022	0.891783369131964
GO:0005026	transforming growth factor beta receptor activity, type II	1/1183	12/18639	0.0833333333333333	1.31297548605241	0.544842989908022	0.891783369131964
GO:0005247	voltage-gated chloride channel activity	1/1183	12/18639	0.0833333333333333	1.31297548605241	0.544842989908022	0.891783369131964
GO:0005527	macrolide binding	1/1183	12/18639	0.0833333333333333	1.31297548605241	0.544842989908022	0.891783369131964
GO:0008603	cAMP-dependent protein kinase regulator activity	1/1183	12/18639	0.0833333333333333	1.31297548605241	0.544842989908022	0.891783369131964
GO:0015166	polyol transmembrane transporter activity	1/1183	12/18639	0.0833333333333333	1.31297548605241	0.544842989908022	0.891783369131964
GO:0016361	activin receptor activity, type I	1/1183	12/18639	0.0833333333333333	1.31297548605241	0.544842989908022	0.891783369131964
GO:0016362	activin receptor activity, type II	1/1183	12/18639	0.0833333333333333	1.31297548605241	0.544842989908022	0.891783369131964
GO:0016423	tRNA (guanine) methyltransferase activity	1/1183	12/18639	0.0833333333333333	1.31297548605241	0.544842989908022	0.891783369131964
GO:0017002	activin receptor activity	1/1183	12/18639	0.0833333333333333	1.31297548605241	0.544842989908022	0.891783369131964
GO:0017166	vinculin binding	1/1183	12/18639	0.0833333333333333	1.31297548605241	0.544842989908022	0.891783369131964
GO:0035014	phosphatidylinositol 3-kinase regulator activity	1/1183	12/18639	0.0833333333333333	1.31297548605241	0.544842989908022	0.891783369131964
GO:0035197	siRNA binding	1/1183	12/18639	0.0833333333333333	1.31297548605241	0.544842989908022	0.891783369131964
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/1183	12/18639	0.0833333333333333	1.31297548605241	0.544842989908022	0.891783369131964
GO:0070008	serine-type exopeptidase activity	1/1183	12/18639	0.0833333333333333	1.31297548605241	0.544842989908022	0.891783369131964
GO:0070410	co-SMAD binding	1/1183	12/18639	0.0833333333333333	1.31297548605241	0.544842989908022	0.891783369131964
GO:0097677	STAT family protein binding	1/1183	12/18639	0.0833333333333333	1.31297548605241	0.544842989908022	0.891783369131964
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	1/1183	12/18639	0.0833333333333333	1.31297548605241	0.544842989908022	0.891783369131964
GO:1990247	N6-methyladenosine-containing RNA reader activity	1/1183	12/18639	0.0833333333333333	1.31297548605241	0.544842989908022	0.891783369131964
GO:0019905	syntaxin binding	4/1183	61/18639	0.0655737704918033	1.03316103820517	0.547099475168997	0.894140187029927
GO:0140303	intramembrane lipid transporter activity	3/1183	45/18639	0.0666666666666667	1.05038038884193	0.550638345513242	0.898582694988077
GO:0004222	metalloendopeptidase activity	7/1183	110/18639	0.0636363636363636	1.00263582571275	0.552789764772372	0.900751179204982
GO:0004181	metallocarboxypeptidase activity	2/1183	29/18639	0.0689655172413793	1.08660040225027	0.557374179099165	0.904184779427535
GO:0005416	amino acid:monoatomic cation symporter activity	2/1183	29/18639	0.0689655172413793	1.08660040225027	0.557374179099165	0.904184779427535
GO:0051861	glycolipid binding	2/1183	29/18639	0.0689655172413793	1.08660040225027	0.557374179099165	0.904184779427535
GO:0030291	protein serine/threonine kinase inhibitor activity	3/1183	46/18639	0.0652173913043478	1.02754603256275	0.565750347134481	0.906574663953985
GO:0019903	protein phosphatase binding	9/1183	144/18639	0.0625	0.984731614539307	0.568011648413298	0.906574663953985
GO:0043022	ribosome binding	7/1183	112/18639	0.0625	0.984731614539307	0.572161868674641	0.906574663953985
GO:0043021	ribonucleoprotein complex binding	11/1183	177/18639	0.0621468926553672	0.979168159089932	0.573151202479923	0.906574663953985
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/1183	13/18639	0.0769230769230769	1.21197737174069	0.573749992803755	0.906574663953985
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	1/1183	13/18639	0.0769230769230769	1.21197737174069	0.573749992803755	0.906574663953985
GO:0005542	folic acid binding	1/1183	13/18639	0.0769230769230769	1.21197737174069	0.573749992803755	0.906574663953985
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	1/1183	13/18639	0.0769230769230769	1.21197737174069	0.573749992803755	0.906574663953985
GO:0019855	calcium channel inhibitor activity	1/1183	13/18639	0.0769230769230769	1.21197737174069	0.573749992803755	0.906574663953985
GO:0032396	inhibitory MHC class I receptor activity	1/1183	13/18639	0.0769230769230769	1.21197737174069	0.573749992803755	0.906574663953985
GO:0046974	histone H3K9 methyltransferase activity	1/1183	13/18639	0.0769230769230769	1.21197737174069	0.573749992803755	0.906574663953985
GO:0046975	histone H3K36 methyltransferase activity	1/1183	13/18639	0.0769230769230769	1.21197737174069	0.573749992803755	0.906574663953985
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	1/1183	13/18639	0.0769230769230769	1.21197737174069	0.573749992803755	0.906574663953985
GO:0061459	L-arginine transmembrane transporter activity	1/1183	13/18639	0.0769230769230769	1.21197737174069	0.573749992803755	0.906574663953985
GO:0070123	transforming growth factor beta receptor activity, type III	1/1183	13/18639	0.0769230769230769	1.21197737174069	0.573749992803755	0.906574663953985
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	1/1183	13/18639	0.0769230769230769	1.21197737174069	0.573749992803755	0.906574663953985
GO:0089720	caspase binding	1/1183	13/18639	0.0769230769230769	1.21197737174069	0.573749992803755	0.906574663953985
GO:0140333	glycerophospholipid flippase activity	1/1183	13/18639	0.0769230769230769	1.21197737174069	0.573749992803755	0.906574663953985
GO:0008106	alcohol dehydrogenase (NADP+) activity	2/1183	30/18639	0.0666666666666667	1.05038038884193	0.576016764349077	0.907537204262215
GO:0031624	ubiquitin conjugating enzyme binding	2/1183	30/18639	0.0666666666666667	1.05038038884193	0.576016764349077	0.907537204262215
GO:0043495	protein-membrane adaptor activity	3/1183	47/18639	0.0638297872340425	1.00568335101887	0.580546584079237	0.912483648220927
GO:0015101	organic cation transmembrane transporter activity	5/1183	81/18639	0.0617283950617284	0.972574434112896	0.590695932474939	0.912483648220927
GO:0005310	dicarboxylic acid transmembrane transporter activity	2/1183	31/18639	0.0645161290322581	1.01649715049219	0.594078268278513	0.912483648220927
GO:0005452	solute:inorganic anion antiporter activity	2/1183	31/18639	0.0645161290322581	1.01649715049219	0.594078268278513	0.912483648220927
GO:0016878	acid-thiol ligase activity	2/1183	31/18639	0.0645161290322581	1.01649715049219	0.594078268278513	0.912483648220927
GO:0072349	modified amino acid transmembrane transporter activity	2/1183	31/18639	0.0645161290322581	1.01649715049219	0.594078268278513	0.912483648220927
GO:0032266	phosphatidylinositol-3-phosphate binding	3/1183	48/18639	0.0625	0.984731614539307	0.595019604316207	0.912483648220927
GO:0004065	arylsulfatase activity	1/1183	14/18639	0.0714285714285714	1.12540755947349	0.600822566545469	0.912483648220927
GO:0005545	1-phosphatidylinositol binding	1/1183	14/18639	0.0714285714285714	1.12540755947349	0.600822566545469	0.912483648220927
GO:0008191	metalloendopeptidase inhibitor activity	1/1183	14/18639	0.0714285714285714	1.12540755947349	0.600822566545469	0.912483648220927
GO:0008195	phosphatidate phosphatase activity	1/1183	14/18639	0.0714285714285714	1.12540755947349	0.600822566545469	0.912483648220927
GO:0008331	high voltage-gated calcium channel activity	1/1183	14/18639	0.0714285714285714	1.12540755947349	0.600822566545469	0.912483648220927
GO:0008474	palmitoyl-(protein) hydrolase activity	1/1183	14/18639	0.0714285714285714	1.12540755947349	0.600822566545469	0.912483648220927
GO:0008494	translation activator activity	1/1183	14/18639	0.0714285714285714	1.12540755947349	0.600822566545469	0.912483648220927
GO:0008559	ABC-type xenobiotic transporter activity	1/1183	14/18639	0.0714285714285714	1.12540755947349	0.600822566545469	0.912483648220927
GO:0015386	potassium:proton antiporter activity	1/1183	14/18639	0.0714285714285714	1.12540755947349	0.600822566545469	0.912483648220927
GO:0015926	glucosidase activity	1/1183	14/18639	0.0714285714285714	1.12540755947349	0.600822566545469	0.912483648220927
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	1/1183	14/18639	0.0714285714285714	1.12540755947349	0.600822566545469	0.912483648220927
GO:0042813	Wnt receptor activity	1/1183	14/18639	0.0714285714285714	1.12540755947349	0.600822566545469	0.912483648220927
GO:0044548	S100 protein binding	1/1183	14/18639	0.0714285714285714	1.12540755947349	0.600822566545469	0.912483648220927
GO:0046030	inositol trisphosphate phosphatase activity	1/1183	14/18639	0.0714285714285714	1.12540755947349	0.600822566545469	0.912483648220927
GO:0061783	peptidoglycan muralytic activity	1/1183	14/18639	0.0714285714285714	1.12540755947349	0.600822566545469	0.912483648220927
GO:0070742	C2H2 zinc finger domain binding	1/1183	14/18639	0.0714285714285714	1.12540755947349	0.600822566545469	0.912483648220927
GO:0071933	Arp2/3 complex binding	1/1183	14/18639	0.0714285714285714	1.12540755947349	0.600822566545469	0.912483648220927
GO:0098599	palmitoyl hydrolase activity	1/1183	14/18639	0.0714285714285714	1.12540755947349	0.600822566545469	0.912483648220927
GO:0098821	BMP receptor activity	1/1183	14/18639	0.0714285714285714	1.12540755947349	0.600822566545469	0.912483648220927
GO:0001222	transcription corepressor binding	3/1183	49/18639	0.0612244897959184	0.96463505097728	0.609163320720126	0.923869579208502
GO:0031369	translation initiation factor binding	2/1183	32/18639	0.0625	0.984731614539307	0.611557296471274	0.924938176292879
GO:0051059	NF-kappaB binding	2/1183	32/18639	0.0625	0.984731614539307	0.611557296471274	0.924938176292879
GO:0005254	chloride channel activity	5/1183	83/18639	0.0602409638554217	0.949138905580055	0.612557181689977	0.92517257096624
GO:0015605	organophosphate ester transmembrane transporter activity	3/1183	50/18639	0.06	0.945342349957734	0.622972922115317	0.931608490678891
GO:0003924	GTPase activity	20/1183	331/18639	0.0604229607250755	0.95200639472078	0.623379413889359	0.931608490678891
GO:0000774	adenyl-nucleotide exchange factor activity	1/1183	15/18639	0.0666666666666667	1.05038038884193	0.626177031177775	0.931608490678891
GO:0004467	long-chain fatty acid-CoA ligase activity	1/1183	15/18639	0.0666666666666667	1.05038038884193	0.626177031177775	0.931608490678891
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/1183	15/18639	0.0666666666666667	1.05038038884193	0.626177031177775	0.931608490678891
GO:0015556	C4-dicarboxylate transmembrane transporter activity	1/1183	15/18639	0.0666666666666667	1.05038038884193	0.626177031177775	0.931608490678891
GO:0015929	hexosaminidase activity	1/1183	15/18639	0.0666666666666667	1.05038038884193	0.626177031177775	0.931608490678891
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/1183	15/18639	0.0666666666666667	1.05038038884193	0.626177031177775	0.931608490678891
GO:0030553	cGMP binding	1/1183	15/18639	0.0666666666666667	1.05038038884193	0.626177031177775	0.931608490678891
GO:0031005	filamin binding	1/1183	15/18639	0.0666666666666667	1.05038038884193	0.626177031177775	0.931608490678891
GO:0047372	monoacylglycerol lipase activity	1/1183	15/18639	0.0666666666666667	1.05038038884193	0.626177031177775	0.931608490678891
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	2/1183	33/18639	0.0606060606060606	0.95489126258357	0.6284549701688	0.933728890549302
GO:0005548	phospholipid transporter activity	4/1183	68/18639	0.0588235294117647	0.926806225448759	0.633857455605662	0.940479558114092
GO:0005272	sodium channel activity	3/1183	51/18639	0.0588235294117647	0.926806225448759	0.636444786675051	0.942214273548065
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	16/1183	268/18639	0.0597014925373134	0.940639154186801	0.636747545594126	0.942214273548065
GO:0015276	ligand-gated monoatomic ion channel activity	11/1183	186/18639	0.0591397849462366	0.931789054617839	0.63943969767025	0.944921010727292
GO:0008376	acetylgalactosaminyltransferase activity	2/1183	34/18639	0.0588235294117647	0.926806225448759	0.64477461305604	0.94510618699635
GO:0015035	protein-disulfide reductase activity	2/1183	34/18639	0.0588235294117647	0.926806225448759	0.64477461305604	0.94510618699635
GO:0016279	protein-lysine N-methyltransferase activity	4/1183	69/18639	0.0579710144927536	0.913374251166893	0.645335683885572	0.94510618699635
GO:0000062	fatty-acyl-CoA binding	1/1183	16/18639	0.0625	0.984731614539307	0.649922336811188	0.94510618699635
GO:0015385	sodium:proton antiporter activity	1/1183	16/18639	0.0625	0.984731614539307	0.649922336811188	0.94510618699635
GO:0017070	U6 snRNA binding	1/1183	16/18639	0.0625	0.984731614539307	0.649922336811188	0.94510618699635
GO:0030275	LRR domain binding	1/1183	16/18639	0.0625	0.984731614539307	0.649922336811188	0.94510618699635
GO:0031435	mitogen-activated protein kinase kinase kinase binding	1/1183	16/18639	0.0625	0.984731614539307	0.649922336811188	0.94510618699635
GO:0034450	ubiquitin-ubiquitin ligase activity	1/1183	16/18639	0.0625	0.984731614539307	0.649922336811188	0.94510618699635
GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	1/1183	16/18639	0.0625	0.984731614539307	0.649922336811188	0.94510618699635
GO:0140327	flippase activity	1/1183	16/18639	0.0625	0.984731614539307	0.649922336811188	0.94510618699635
GO:0140328	floppase activity	1/1183	16/18639	0.0625	0.984731614539307	0.649922336811188	0.94510618699635
GO:0022834	ligand-gated channel activity	11/1183	188/18639	0.0585106382978723	0.921876405100628	0.653408111950465	0.948914963641591
GO:0016278	lysine N-methyltransferase activity	4/1183	70/18639	0.0571428571428571	0.900326047578795	0.656573777987414	0.950924781102409
GO:0016782	transferase activity, transferring sulphur-containing groups	4/1183	70/18639	0.0571428571428571	0.900326047578795	0.656573777987414	0.950924781102409
GO:0005343	organic acid:sodium symporter activity	2/1183	35/18639	0.0571428571428571	0.900326047578795	0.660521467617273	0.950924781102409
GO:0017046	peptide hormone binding	3/1183	53/18639	0.0566037735849057	0.891832405620504	0.662366263762765	0.950924781102409
GO:1901505	carbohydrate derivative transmembrane transporter activity	3/1183	53/18639	0.0566037735849057	0.891832405620504	0.662366263762765	0.950924781102409
GO:0140299	molecular sensor activity	4/1183	71/18639	0.0563380281690141	0.887645399021347	0.667569581416955	0.950924781102409
GO:0004549	tRNA-specific ribonuclease activity	1/1183	17/18639	0.0588235294117647	0.926806225448759	0.672160530203894	0.950924781102409
GO:0008484	sulfuric ester hydrolase activity	1/1183	17/18639	0.0588235294117647	0.926806225448759	0.672160530203894	0.950924781102409
GO:0008569	minus-end-directed microtubule motor activity	1/1183	17/18639	0.0588235294117647	0.926806225448759	0.672160530203894	0.950924781102409
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/1183	17/18639	0.0588235294117647	0.926806225448759	0.672160530203894	0.950924781102409
GO:0030548	acetylcholine receptor regulator activity	1/1183	17/18639	0.0588235294117647	0.926806225448759	0.672160530203894	0.950924781102409
GO:0031489	myosin V binding	1/1183	17/18639	0.0588235294117647	0.926806225448759	0.672160530203894	0.950924781102409
GO:0032183	SUMO binding	1/1183	17/18639	0.0588235294117647	0.926806225448759	0.672160530203894	0.950924781102409
GO:0045125	bioactive lipid receptor activity	1/1183	17/18639	0.0588235294117647	0.926806225448759	0.672160530203894	0.950924781102409
GO:0045236	CXCR chemokine receptor binding	1/1183	17/18639	0.0588235294117647	0.926806225448759	0.672160530203894	0.950924781102409
GO:0048038	quinone binding	1/1183	17/18639	0.0588235294117647	0.926806225448759	0.672160530203894	0.950924781102409
GO:0051787	misfolded protein binding	1/1183	17/18639	0.0588235294117647	0.926806225448759	0.672160530203894	0.950924781102409
GO:0070403	NAD+ binding	1/1183	17/18639	0.0588235294117647	0.926806225448759	0.672160530203894	0.950924781102409
GO:1901567	fatty acid derivative binding	1/1183	17/18639	0.0588235294117647	0.926806225448759	0.672160530203894	0.950924781102409
GO:1990226	histone methyltransferase binding	1/1183	17/18639	0.0588235294117647	0.926806225448759	0.672160530203894	0.950924781102409
GO:0003925	G protein activity	3/1183	54/18639	0.0555555555555556	0.875316990701606	0.674813838077965	0.95344664863919
GO:0004033	aldo-keto reductase (NADPH) activity	2/1183	36/18639	0.0555555555555556	0.875316990701606	0.675702438574993	0.953471868865486
GO:0004721	phosphoprotein phosphatase activity	10/1183	175/18639	0.0571428571428571	0.900326047578795	0.67943313168591	0.954491792518159
GO:0008017	microtubule binding	16/1183	276/18639	0.0579710144927536	0.913374251166893	0.682562423181508	0.954491792518159
GO:0004521	RNA endonuclease activity	4/1183	73/18639	0.0547945205479452	0.863326346993365	0.688828460454043	0.954491792518159
GO:0019213	deacetylase activity	2/1183	37/18639	0.0540540540540541	0.851659774736698	0.690325861121148	0.954491792518159
GO:0022829	wide pore channel activity	2/1183	37/18639	0.0540540540540541	0.851659774736698	0.690325861121148	0.954491792518159
GO:0072341	modified amino acid binding	5/1183	91/18639	0.0549450549450549	0.865698122671918	0.692800882735453	0.954491792518159
GO:0008308	voltage-gated monoatomic anion channel activity	1/1183	18/18639	0.0555555555555556	0.875316990701606	0.692987191828252	0.954491792518159
GO:0008409	5'-3' exonuclease activity	1/1183	18/18639	0.0555555555555556	0.875316990701606	0.692987191828252	0.954491792518159
GO:0008525	phosphatidylcholine transporter activity	1/1183	18/18639	0.0555555555555556	0.875316990701606	0.692987191828252	0.954491792518159
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	1/1183	18/18639	0.0555555555555556	0.875316990701606	0.692987191828252	0.954491792518159
GO:0016854	racemase and epimerase activity	1/1183	18/18639	0.0555555555555556	0.875316990701606	0.692987191828252	0.954491792518159
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/1183	18/18639	0.0555555555555556	0.875316990701606	0.692987191828252	0.954491792518159
GO:0017128	phospholipid scramblase activity	1/1183	18/18639	0.0555555555555556	0.875316990701606	0.692987191828252	0.954491792518159
GO:0022851	GABA-gated chloride ion channel activity	1/1183	18/18639	0.0555555555555556	0.875316990701606	0.692987191828252	0.954491792518159
GO:0032393	MHC class I receptor activity	1/1183	18/18639	0.0555555555555556	0.875316990701606	0.692987191828252	0.954491792518159
GO:0034185	apolipoprotein binding	1/1183	18/18639	0.0555555555555556	0.875316990701606	0.692987191828252	0.954491792518159
GO:0098641	cadherin binding involved in cell-cell adhesion	1/1183	18/18639	0.0555555555555556	0.875316990701606	0.692987191828252	0.954491792518159
GO:0099602	neurotransmitter receptor regulator activity	1/1183	18/18639	0.0555555555555556	0.875316990701606	0.692987191828252	0.954491792518159
GO:1901611	phosphatidylglycerol binding	1/1183	18/18639	0.0555555555555556	0.875316990701606	0.692987191828252	0.954491792518159
GO:0005525	GTP binding	22/1183	378/18639	0.0582010582010582	0.916998752163587	0.694693650079522	0.955640134217434
GO:0003712	transcription coregulator activity	29/1183	495/18639	0.0585858585858586	0.923061553830785	0.700796427994951	0.957758995985784
GO:0044183	protein folding chaperone	4/1183	75/18639	0.0533333333333333	0.840304311073542	0.709105718019218	0.957758995985784
GO:0015932	nucleobase-containing compound transmembrane transporter activity	3/1183	57/18639	0.0526315789473684	0.829247675401522	0.710109992525458	0.957758995985784
GO:0003756	protein disulfide isomerase activity	1/1183	19/18639	0.0526315789473684	0.829247675401522	0.712491845287636	0.957758995985784
GO:0004890	GABA-A receptor activity	1/1183	19/18639	0.0526315789473684	0.829247675401522	0.712491845287636	0.957758995985784
GO:0005229	intracellularly calcium-gated chloride channel activity	1/1183	19/18639	0.0526315789473684	0.829247675401522	0.712491845287636	0.957758995985784
GO:0008381	mechanosensitive monoatomic ion channel activity	1/1183	19/18639	0.0526315789473684	0.829247675401522	0.712491845287636	0.957758995985784
GO:0008574	plus-end-directed microtubule motor activity	1/1183	19/18639	0.0526315789473684	0.829247675401522	0.712491845287636	0.957758995985784
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	1/1183	19/18639	0.0526315789473684	0.829247675401522	0.712491845287636	0.957758995985784
GO:0022821	solute:potassium antiporter activity	1/1183	19/18639	0.0526315789473684	0.829247675401522	0.712491845287636	0.957758995985784
GO:0030506	ankyrin binding	1/1183	19/18639	0.0526315789473684	0.829247675401522	0.712491845287636	0.957758995985784
GO:0034987	immunoglobulin receptor binding	1/1183	19/18639	0.0526315789473684	0.829247675401522	0.712491845287636	0.957758995985784
GO:0042577	lipid phosphatase activity	1/1183	19/18639	0.0526315789473684	0.829247675401522	0.712491845287636	0.957758995985784
GO:0042800	histone H3K4 methyltransferase activity	1/1183	19/18639	0.0526315789473684	0.829247675401522	0.712491845287636	0.957758995985784
GO:0046624	sphingolipid transporter activity	1/1183	19/18639	0.0526315789473684	0.829247675401522	0.712491845287636	0.957758995985784
GO:0097001	ceramide binding	1/1183	19/18639	0.0526315789473684	0.829247675401522	0.712491845287636	0.957758995985784
GO:0120227	acyl-CoA binding	1/1183	19/18639	0.0526315789473684	0.829247675401522	0.712491845287636	0.957758995985784
GO:0141147	intracellularly calcium-gated channel activity	1/1183	19/18639	0.0526315789473684	0.829247675401522	0.712491845287636	0.957758995985784
GO:0016853	isomerase activity	10/1183	180/18639	0.0555555555555556	0.875316990701606	0.712852586053346	0.957758995985784
GO:0042562	hormone binding	5/1183	94/18639	0.0531914893617021	0.838069459182389	0.719771754087648	0.965870184713204
GO:0008276	protein methyltransferase activity	5/1183	95/18639	0.0526315789473684	0.829247675401522	0.7283768241474	0.969154819981883
GO:0001972	retinoic acid binding	1/1183	20/18639	0.05	0.787785291631446	0.730758340831391	0.969154819981883
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	1/1183	20/18639	0.05	0.787785291631446	0.730758340831391	0.969154819981883
GO:0005326	neurotransmitter transmembrane transporter activity	1/1183	20/18639	0.05	0.787785291631446	0.730758340831391	0.969154819981883
GO:0042288	MHC class I protein binding	1/1183	20/18639	0.05	0.787785291631446	0.730758340831391	0.969154819981883
GO:0043024	ribosomal small subunit binding	1/1183	20/18639	0.05	0.787785291631446	0.730758340831391	0.969154819981883
GO:0052745	inositol phosphate phosphatase activity	1/1183	20/18639	0.05	0.787785291631446	0.730758340831391	0.969154819981883
GO:0015036	disulfide oxidoreductase activity	2/1183	40/18639	0.05	0.787785291631446	0.730951399849405	0.969154819981883
GO:0140662	ATP-dependent protein folding chaperone	2/1183	40/18639	0.05	0.787785291631446	0.730951399849405	0.969154819981883
GO:0001786	phosphatidylserine binding	3/1183	59/18639	0.0508474576271186	0.801137584709945	0.731955284132436	0.969154819981883
GO:0004879	nuclear receptor activity	3/1183	59/18639	0.0508474576271186	0.801137584709945	0.731955284132436	0.969154819981883
GO:0015291	secondary active transmembrane transporter activity	16/1183	287/18639	0.0557491289198606	0.878366875686629	0.739881764888077	0.973736516043765
GO:0001098	basal transcription machinery binding	3/1183	60/18639	0.05	0.787785291631446	0.742381591504702	0.973736516043765
GO:0001099	basal RNA polymerase II transcription machinery binding	3/1183	60/18639	0.05	0.787785291631446	0.742381591504702	0.973736516043765
GO:0098531	ligand-modulated transcription factor activity	3/1183	60/18639	0.05	0.787785291631446	0.742381591504702	0.973736516043765
GO:0008227	G protein-coupled amine receptor activity	2/1183	41/18639	0.0487804878048781	0.7685710162258	0.743449695249633	0.973736516043765
GO:0030594	neurotransmitter receptor activity	5/1183	97/18639	0.0515463917525773	0.812149785187057	0.745010223019419	0.973736516043765
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	1/1183	21/18639	0.0476190476190476	0.750271706315662	0.747865214605303	0.973736516043765
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	1/1183	21/18639	0.0476190476190476	0.750271706315662	0.747865214605303	0.973736516043765
GO:0005123	death receptor binding	1/1183	21/18639	0.0476190476190476	0.750271706315662	0.747865214605303	0.973736516043765
GO:0005248	voltage-gated sodium channel activity	1/1183	21/18639	0.0476190476190476	0.750271706315662	0.747865214605303	0.973736516043765
GO:0015174	basic amino acid transmembrane transporter activity	1/1183	21/18639	0.0476190476190476	0.750271706315662	0.747865214605303	0.973736516043765
GO:0036122	BMP binding	1/1183	21/18639	0.0476190476190476	0.750271706315662	0.747865214605303	0.973736516043765
GO:0051010	microtubule plus-end binding	1/1183	21/18639	0.0476190476190476	0.750271706315662	0.747865214605303	0.973736516043765
GO:0061891	calcium ion sensor activity	1/1183	21/18639	0.0476190476190476	0.750271706315662	0.747865214605303	0.973736516043765
GO:0015294	solute:monoatomic cation symporter activity	6/1183	116/18639	0.0517241379310345	0.814950301687702	0.752856746984765	0.97907142274147
GO:0003713	transcription coactivator activity	14/1183	256/18639	0.0546875	0.861640162721893	0.755222652394148	0.980111856119729
GO:0031492	nucleosomal DNA binding	2/1183	42/18639	0.0476190476190476	0.750271706315662	0.75544694663475	0.980111856119729
GO:0015297	antiporter activity	7/1183	135/18639	0.0518518518518519	0.816962524654832	0.760783541304396	0.980603983074819
GO:0003774	cytoskeletal motor activity	8/1183	153/18639	0.0522875816993464	0.823827755954453	0.762376028842193	0.980603983074819
GO:0005243	gap junction channel activity	1/1183	22/18639	0.0454545454545455	0.716168446937678	0.763886025171525	0.980603983074819
GO:0015377	chloride:monoatomic cation symporter activity	1/1183	22/18639	0.0454545454545455	0.716168446937678	0.763886025171525	0.980603983074819
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	1/1183	22/18639	0.0454545454545455	0.716168446937678	0.763886025171525	0.980603983074819
GO:0034062	5'-3' RNA polymerase activity	1/1183	22/18639	0.0454545454545455	0.716168446937678	0.763886025171525	0.980603983074819
GO:0070034	telomerase RNA binding	1/1183	22/18639	0.0454545454545455	0.716168446937678	0.763886025171525	0.980603983074819
GO:0097747	RNA polymerase activity	1/1183	22/18639	0.0454545454545455	0.716168446937678	0.763886025171525	0.980603983074819
GO:0140784	metal ion sensor activity	1/1183	22/18639	0.0454545454545455	0.716168446937678	0.763886025171525	0.980603983074819
GO:0004712	protein serine/threonine/tyrosine kinase activity	2/1183	43/18639	0.0465116279069767	0.732823527099019	0.766956347528383	0.981666149846935
GO:0106310	protein serine kinase activity	20/1183	361/18639	0.0554016620498615	0.872892289896338	0.767385036623421	0.981666149846935
GO:0099094	ligand-gated monoatomic cation channel activity	7/1183	136/18639	0.0514705882352941	0.810955447267664	0.767402944537878	0.981666149846935
GO:0022824	transmitter-gated monoatomic ion channel activity	3/1183	63/18639	0.0476190476190476	0.750271706315662	0.77172624509102	0.984895382721057
GO:0022835	transmitter-gated channel activity	3/1183	63/18639	0.0476190476190476	0.750271706315662	0.77172624509102	0.984895382721057
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	1/1183	23/18639	0.0434782608695652	0.68503068837517	0.778889668735047	0.985993280075002
GO:0005212	structural constituent of eye lens	1/1183	23/18639	0.0434782608695652	0.68503068837517	0.778889668735047	0.985993280075002
GO:0016917	GABA receptor activity	1/1183	23/18639	0.0434782608695652	0.68503068837517	0.778889668735047	0.985993280075002
GO:0042171	lysophosphatidic acid acyltransferase activity	1/1183	23/18639	0.0434782608695652	0.68503068837517	0.778889668735047	0.985993280075002
GO:0071617	lysophospholipid acyltransferase activity	1/1183	23/18639	0.0434782608695652	0.68503068837517	0.778889668735047	0.985993280075002
GO:0099186	structural constituent of postsynapse	1/1183	23/18639	0.0434782608695652	0.68503068837517	0.778889668735047	0.985993280075002
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	1/1183	23/18639	0.0434782608695652	0.68503068837517	0.778889668735047	0.985993280075002
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	4/1183	83/18639	0.0481927710843374	0.759311124464044	0.78050985995543	0.986903344862813
GO:0003823	antigen binding	9/1183	174/18639	0.0517241379310345	0.814950301687702	0.78184844785978	0.987455652141244
GO:0004674	protein serine/threonine kinase activity	24/1183	433/18639	0.0554272517321016	0.873295473402064	0.783523970274409	0.988431736694099
GO:0004252	serine-type endopeptidase activity	9/1183	176/18639	0.0511363636363636	0.805689502804887	0.792849750531321	0.995722521207748
GO:0004622	lysophospholipase activity	1/1183	24/18639	0.0416666666666667	0.656487743026205	0.792940674422973	0.995722521207748
GO:0050699	WW domain binding	1/1183	24/18639	0.0416666666666667	0.656487743026205	0.792940674422973	0.995722521207748
GO:0070840	dynein complex binding	1/1183	24/18639	0.0416666666666667	0.656487743026205	0.792940674422973	0.995722521207748
GO:0008236	serine-type peptidase activity	10/1183	194/18639	0.0515463917525773	0.812149785187057	0.793998002861666	0.995908147919272
GO:0022836	gated channel activity	17/1183	318/18639	0.0534591194968553	0.84228616086381	0.801281328422538	0.999999999649628
GO:0000030	mannosyltransferase activity	1/1183	25/18639	0.04	0.630228233305156	0.806099480877855	0.999999999649628
GO:0003707	nuclear steroid receptor activity	1/1183	25/18639	0.04	0.630228233305156	0.806099480877855	0.999999999649628
GO:0005251	delayed rectifier potassium channel activity	1/1183	25/18639	0.04	0.630228233305156	0.806099480877855	0.999999999649628
GO:0015271	outward rectifier potassium channel activity	1/1183	25/18639	0.04	0.630228233305156	0.806099480877855	0.999999999649628
GO:0015296	monoatomic anion:monoatomic cation symporter activity	1/1183	25/18639	0.04	0.630228233305156	0.806099480877855	0.999999999649628
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	1/1183	25/18639	0.04	0.630228233305156	0.806099480877855	0.999999999649628
GO:0017025	TBP-class protein binding	1/1183	25/18639	0.04	0.630228233305156	0.806099480877855	0.999999999649628
GO:0042054	histone methyltransferase activity	3/1183	67/18639	0.0447761194029851	0.7054793656401	0.806533696010748	0.999999999649628
GO:0099095	ligand-gated monoatomic anion channel activity	2/1183	47/18639	0.0425531914893617	0.670455567345911	0.808389422559966	0.999999999649628
GO:0140938	histone H3 methyltransferase activity	2/1183	47/18639	0.0425531914893617	0.670455567345911	0.808389422559966	0.999999999649628
GO:0000149	SNARE binding	5/1183	106/18639	0.0471698113207547	0.74319367135042	0.810553087563871	0.999999999649628
GO:0017171	serine hydrolase activity	10/1183	198/18639	0.0505050505050505	0.795742718819642	0.813797331227071	0.999999999649628
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	2/1183	48/18639	0.0416666666666667	0.656487743026205	0.81766637117926	0.999999999649628
GO:0004529	DNA exonuclease activity	1/1183	26/18639	0.0384615384615385	0.605988685870343	0.818422695346615	0.999999999649628
GO:0005112	Notch binding	1/1183	26/18639	0.0384615384615385	0.605988685870343	0.818422695346615	0.999999999649628
GO:0008157	protein phosphatase 1 binding	1/1183	26/18639	0.0384615384615385	0.605988685870343	0.818422695346615	0.999999999649628
GO:0051139	metal cation:proton antiporter activity	1/1183	26/18639	0.0384615384615385	0.605988685870343	0.818422695346615	0.999999999649628
GO:0052742	phosphatidylinositol kinase activity	1/1183	26/18639	0.0384615384615385	0.605988685870343	0.818422695346615	0.999999999649628
GO:0004519	endonuclease activity	6/1183	127/18639	0.047244094488189	0.74436405508483	0.824091849968606	0.999999999649628
GO:0003727	single-stranded RNA binding	4/1183	89/18639	0.0449438202247191	0.708121610455232	0.824358545493915	0.999999999649628
GO:0001653	peptide receptor activity	6/1183	128/18639	0.046875	0.73854871090448	0.829670673398948	0.999999999649628
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	6/1183	128/18639	0.046875	0.73854871090448	0.829670673398948	0.999999999649628
GO:0004683	calcium/calmodulin-dependent protein kinase activity	1/1183	27/18639	0.037037037037037	0.583544660467737	0.829963336371971	0.999999999649628
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	1/1183	27/18639	0.037037037037037	0.583544660467737	0.829963336371971	0.999999999649628
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	1/1183	27/18639	0.037037037037037	0.583544660467737	0.829963336371971	0.999999999649628
GO:0016791	phosphatase activity	14/1183	273/18639	0.0512820512820513	0.80798491449379	0.830346766615519	0.999999999649628
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	6/1183	130/18639	0.0461538461538462	0.727186423044411	0.840403181527106	0.999999999649628
GO:0005242	inward rectifier potassium channel activity	1/1183	28/18639	0.0357142857142857	0.562703779736747	0.840771061123312	0.999999999649628
GO:0051393	alpha-actinin binding	1/1183	28/18639	0.0357142857142857	0.562703779736747	0.840771061123312	0.999999999649628
GO:0051537	2 iron, 2 sulfur cluster binding	1/1183	28/18639	0.0357142857142857	0.562703779736747	0.840771061123312	0.999999999649628
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	1/1183	28/18639	0.0357142857142857	0.562703779736747	0.840771061123312	0.999999999649628
GO:0005048	signal sequence binding	2/1183	51/18639	0.0392156862745098	0.61787081696584	0.843125896268248	0.999999999649628
GO:0051213	dioxygenase activity	4/1183	93/18639	0.043010752688172	0.677664766994792	0.849364919799935	0.999999999649628
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	3/1183	73/18639	0.0410958904109589	0.647494760245024	0.850280914347496	0.999999999649628
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	2/1183	52/18639	0.0384615384615385	0.605988685870343	0.850867876200869	0.999999999649628
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	1/1183	29/18639	0.0344827586206897	0.543300201125135	0.85089237833846	0.999999999649628
GO:0097472	cyclin-dependent protein kinase activity	1/1183	29/18639	0.0344827586206897	0.543300201125135	0.85089237833846	0.999999999649628
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	2/1183	53/18639	0.0377358490566038	0.594554937080336	0.858260096296481	0.999999999649628
GO:0016769	transferase activity, transferring nitrogenous groups	1/1183	30/18639	0.0333333333333333	0.525190194420964	0.86037084778637	0.999999999649628
GO:0031210	phosphatidylcholine binding	1/1183	30/18639	0.0333333333333333	0.525190194420964	0.86037084778637	0.999999999649628
GO:0048019	receptor antagonist activity	1/1183	30/18639	0.0333333333333333	0.525190194420964	0.86037084778637	0.999999999649628
GO:0098918	structural constituent of synapse	1/1183	30/18639	0.0333333333333333	0.525190194420964	0.86037084778637	0.999999999649628
GO:0019003	GDP binding	3/1183	75/18639	0.04	0.630228233305156	0.862817748255405	0.999999999649628
GO:0050661	NADP binding	2/1183	54/18639	0.037037037037037	0.583544660467737	0.865315721612578	0.999999999649628
GO:0051536	iron-sulfur cluster binding	3/1183	76/18639	0.0394736842105263	0.621935756551141	0.868733152204776	0.999999999649628
GO:0016411	acylglycerol O-acyltransferase activity	1/1183	31/18639	0.032258064516129	0.508248575246094	0.869247267103299	0.999999999649628
GO:0047499	calcium-independent phospholipase A2 activity	1/1183	31/18639	0.032258064516129	0.508248575246094	0.869247267103299	0.999999999649628
GO:0022832	voltage-gated channel activity	8/1183	175/18639	0.0457142857142857	0.720260838063036	0.873021639900628	0.999999999649628
GO:0051540	metal cluster binding	3/1183	77/18639	0.038961038961039	0.613858668803724	0.874422242738508	0.999999999649628
GO:0015106	bicarbonate transmembrane transporter activity	1/1183	32/18639	0.03125	0.492365807269653	0.877559846801106	0.999999999649628
GO:0030515	snoRNA binding	1/1183	32/18639	0.03125	0.492365807269653	0.877559846801106	0.999999999649628
GO:0042910	xenobiotic transmembrane transporter activity	1/1183	32/18639	0.03125	0.492365807269653	0.877559846801106	0.999999999649628
GO:0047498	calcium-dependent phospholipase A2 activity	1/1183	32/18639	0.03125	0.492365807269653	0.877559846801106	0.999999999649628
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	2/1183	56/18639	0.0357142857142857	0.562703779736747	0.878468524842274	0.999999999649628
GO:0016835	carbon-oxygen lyase activity	3/1183	79/18639	0.0379746835443038	0.598317943011224	0.885148299117096	0.999999999649628
GO:0019239	deaminase activity	1/1183	33/18639	0.0303030303030303	0.477445631291785	0.885344374195866	0.999999999649628
GO:0030296	protein tyrosine kinase activator activity	1/1183	33/18639	0.0303030303030303	0.477445631291785	0.885344374195866	0.999999999649628
GO:0071889	14-3-3 protein binding	1/1183	33/18639	0.0303030303030303	0.477445631291785	0.885344374195866	0.999999999649628
GO:0015079	potassium ion transmembrane transporter activity	7/1183	160/18639	0.04375	0.689312130177515	0.88830967681752	0.999999999649628
GO:0004540	RNA nuclease activity	5/1183	121/18639	0.0413223140495868	0.651062224488798	0.889228677512999	0.999999999649628
GO:0000049	tRNA binding	3/1183	80/18639	0.0375	0.590838968723584	0.890198513909253	0.999999999649628
GO:0008175	tRNA methyltransferase activity	1/1183	34/18639	0.0294117647058824	0.46340311272438	0.892634366957679	0.999999999649628
GO:0015020	glucuronosyltransferase activity	1/1183	34/18639	0.0294117647058824	0.46340311272438	0.892634366957679	0.999999999649628
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	1/1183	34/18639	0.0294117647058824	0.46340311272438	0.892634366957679	0.999999999649628
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	1/1183	34/18639	0.0294117647058824	0.46340311272438	0.892634366957679	0.999999999649628
GO:0052866	phosphatidylinositol phosphate phosphatase activity	1/1183	34/18639	0.0294117647058824	0.46340311272438	0.892634366957679	0.999999999649628
GO:0008528	G protein-coupled peptide receptor activity	5/1183	122/18639	0.040983606557377	0.645725648878234	0.893298299003136	0.999999999649628
GO:0033192	calmodulin-dependent protein phosphatase activity	3/1183	81/18639	0.037037037037037	0.583544660467737	0.895048890345477	0.999999999649628
GO:0140791	histone H2AXS140 phosphatase activity	3/1183	81/18639	0.037037037037037	0.583544660467737	0.895048890345477	0.999999999649628
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	3/1183	81/18639	0.037037037037037	0.583544660467737	0.895048890345477	0.999999999649628
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	3/1183	81/18639	0.037037037037037	0.583544660467737	0.895048890345477	0.999999999649628
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	3/1183	81/18639	0.037037037037037	0.583544660467737	0.895048890345477	0.999999999649628
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	3/1183	81/18639	0.037037037037037	0.583544660467737	0.895048890345477	0.999999999649628
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	3/1183	81/18639	0.037037037037037	0.583544660467737	0.895048890345477	0.999999999649628
GO:1990439	MAP kinase serine/threonine phosphatase activity	3/1183	81/18639	0.037037037037037	0.583544660467737	0.895048890345477	0.999999999649628
GO:0004722	protein serine/threonine phosphatase activity	4/1183	103/18639	0.0388349514563107	0.611872071170055	0.89900061091699	0.999999999649628
GO:0004623	phospholipase A2 activity	1/1183	35/18639	0.0285714285714286	0.450163023789397	0.899461216938279	0.999999999649628
GO:0061631	ubiquitin conjugating enzyme activity	1/1183	35/18639	0.0285714285714286	0.450163023789397	0.899461216938279	0.999999999649628
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	3/1183	82/18639	0.0365853658536585	0.57642826216935	0.899705844853073	0.999999999649628
GO:0033549	MAP kinase phosphatase activity	3/1183	82/18639	0.0365853658536585	0.57642826216935	0.899705844853073	0.999999999649628
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	2/1183	60/18639	0.0333333333333333	0.525190194420964	0.901283155319751	0.999999999649628
GO:0015081	sodium ion transmembrane transporter activity	7/1183	164/18639	0.0426829268292683	0.672499639197575	0.902173845566938	0.999999999649628
GO:0000993	RNA polymerase II complex binding	1/1183	36/18639	0.0277777777777778	0.437658495350803	0.905854324891515	0.999999999649628
GO:0004190	aspartic-type endopeptidase activity	1/1183	36/18639	0.0277777777777778	0.437658495350803	0.905854324891515	0.999999999649628
GO:0005484	SNAP receptor activity	1/1183	36/18639	0.0277777777777778	0.437658495350803	0.905854324891515	0.999999999649628
GO:0016836	hydro-lyase activity	2/1183	61/18639	0.0327868852459016	0.516580519102587	0.906327249038199	0.999999999649628
GO:0015293	symporter activity	6/1183	146/18639	0.0410958904109589	0.647494760245024	0.907811310930068	0.999999999649628
GO:0004527	exonuclease activity	3/1183	84/18639	0.0357142857142857	0.562703779736747	0.908464648518052	0.999999999649628
GO:0017018	myosin phosphatase activity	3/1183	84/18639	0.0357142857142857	0.562703779736747	0.908464648518052	0.999999999649628
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	7/1183	167/18639	0.0419161676646707	0.660418807355703	0.911585536564736	0.999999999649628
GO:0030280	structural constituent of skin epidermis	1/1183	37/18639	0.027027027027027	0.425829887368349	0.911841226662915	0.999999999649628
GO:0070001	aspartic-type peptidase activity	1/1183	37/18639	0.027027027027027	0.425829887368349	0.911841226662915	0.999999999649628
GO:0035403	histone H3T6 kinase activity	11/1183	247/18639	0.0445344129554656	0.701671109955133	0.919296707699855	0.999999999649628
GO:0004518	nuclease activity	9/1183	209/18639	0.0430622009569378	0.678475370783063	0.919898394487234	0.999999999649628
GO:0004536	DNA nuclease activity	2/1183	64/18639	0.03125	0.492365807269653	0.920049055392778	0.999999999649628
GO:0000217	DNA secondary structure binding	1/1183	39/18639	0.0256410256410256	0.403992457246895	0.922697932205678	0.999999999649628
GO:0140104	molecular carrier activity	11/1183	249/18639	0.0441767068273092	0.696035197425374	0.923860319240549	0.999999999649628
GO:0000287	magnesium ion binding	10/1183	230/18639	0.0434782608695652	0.68503068837517	0.924095469473626	0.999999999649628
GO:0160215	deacylase activity	2/1183	65/18639	0.0307692307692308	0.484790948696274	0.924186231115204	0.999999999649628
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	1/1183	40/18639	0.025	0.393892645815723	0.927614509958402	0.999999999649628
GO:0030331	nuclear estrogen receptor binding	1/1183	40/18639	0.025	0.393892645815723	0.927614509958402	0.999999999649628
GO:0050997	quaternary ammonium group binding	1/1183	40/18639	0.025	0.393892645815723	0.927614509958402	0.999999999649628
GO:0061791	GTPase motor activity	1/1183	40/18639	0.025	0.393892645815723	0.927614509958402	0.999999999649628
GO:0071949	FAD binding	1/1183	40/18639	0.025	0.393892645815723	0.927614509958402	0.999999999649628
GO:1990606	membrane scission GTPase motor activity	1/1183	40/18639	0.025	0.393892645815723	0.927614509958402	0.999999999649628
GO:0005244	voltage-gated monoatomic ion channel activity	7/1183	173/18639	0.0404624277456647	0.637514108834696	0.928092231905727	0.999999999649628
GO:0001727	lipid kinase activity	1/1183	41/18639	0.024390243902439	0.3842855081129	0.932218630326122	0.999999999649628
GO:0061650	ubiquitin-like protein conjugating enzyme activity	1/1183	41/18639	0.024390243902439	0.3842855081129	0.932218630326122	0.999999999649628
GO:0140828	metal cation:monoatomic cation antiporter activity	1/1183	41/18639	0.024390243902439	0.3842855081129	0.932218630326122	0.999999999649628
GO:0016741	transferase activity, transferring one-carbon groups	9/1183	215/18639	0.0418604651162791	0.659541174389117	0.933792167887668	0.999999999649628
GO:0003777	microtubule motor activity	2/1183	68/18639	0.0294117647058824	0.46340311272438	0.93541835108129	0.999999999649628
GO:1990841	promoter-specific chromatin binding	2/1183	68/18639	0.0294117647058824	0.46340311272438	0.93541835108129	0.999999999649628
GO:0004520	DNA endonuclease activity	1/1183	42/18639	0.0238095238095238	0.375135853157831	0.936530134806399	0.999999999649628
GO:0008307	structural constituent of muscle	1/1183	42/18639	0.0238095238095238	0.375135853157831	0.936530134806399	0.999999999649628
GO:0043175	RNA polymerase core enzyme binding	1/1183	42/18639	0.0238095238095238	0.375135853157831	0.936530134806399	0.999999999649628
GO:0052689	carboxylic ester hydrolase activity	3/1183	92/18639	0.0326086956521739	0.513773016281377	0.936969616402818	0.999999999649628
GO:0002039	p53 binding	2/1183	69/18639	0.0289855072463768	0.456687125583447	0.938798218013235	0.999999999649628
GO:0008080	N-acetyltransferase activity	2/1183	69/18639	0.0289855072463768	0.456687125583447	0.938798218013235	0.999999999649628
GO:0098960	postsynaptic neurotransmitter receptor activity	2/1183	69/18639	0.0289855072463768	0.456687125583447	0.938798218013235	0.999999999649628
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/1183	43/18639	0.0232558139534884	0.36641176354951	0.940567605932066	0.999999999649628
GO:0001046	core promoter sequence-specific DNA binding	1/1183	44/18639	0.0227272727272727	0.358084223468839	0.944348447090507	0.999999999649628
GO:0016790	thiolester hydrolase activity	1/1183	44/18639	0.0227272727272727	0.358084223468839	0.944348447090507	0.999999999649628
GO:0043014	alpha-tubulin binding	1/1183	44/18639	0.0227272727272727	0.358084223468839	0.944348447090507	0.999999999649628
GO:0051539	4 iron, 4 sulfur cluster binding	1/1183	45/18639	0.0222222222222222	0.350126796280642	0.947888957286362	0.999999999649628
GO:0016407	acetyltransferase activity	3/1183	96/18639	0.03125	0.492365807269653	0.94791500391302	0.999999999649628
GO:0046873	metal ion transmembrane transporter activity	21/1183	450/18639	0.0466666666666667	0.735266272189349	0.948018005115246	0.999999999649628
GO:0008168	methyltransferase activity	8/1183	204/18639	0.0392156862745098	0.61787081696584	0.95081248621231	0.999999999649628
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/1183	46/18639	0.0217391304347826	0.342515344187585	0.951204401167734	0.999999999649628
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	1/1183	46/18639	0.0217391304347826	0.342515344187585	0.951204401167734	0.999999999649628
GO:0016887	ATP hydrolysis activity	19/1183	417/18639	0.0455635491606715	0.717885877266065	0.952874623757432	0.999999999649628
GO:0003697	single-stranded DNA binding	4/1183	121/18639	0.0330578512396694	0.520849779591038	0.953148313436969	0.999999999649628
GO:0031491	nucleosome binding	2/1183	74/18639	0.027027027027027	0.425829887368349	0.953321725685578	0.999999999649628
GO:0022843	voltage-gated monoatomic cation channel activity	5/1183	143/18639	0.034965034965035	0.550898805336675	0.95334294540176	0.999999999649628
GO:0061733	protein-lysine-acetyltransferase activity	1/1183	47/18639	0.0212765957446809	0.335227783672956	0.954309074615729	0.999999999649628
GO:0140359	ABC-type transporter activity	1/1183	47/18639	0.0212765957446809	0.335227783672956	0.954309074615729	0.999999999649628
GO:0016757	glycosyltransferase activity	11/1183	267/18639	0.0411985018726592	0.649111476250629	0.955904280421491	0.999999999649628
GO:0016879	ligase activity, forming carbon-nitrogen bonds	1/1183	48/18639	0.0208333333333333	0.328243871513102	0.957216366178207	0.999999999649628
GO:0005267	potassium channel activity	4/1183	124/18639	0.032258064516129	0.508248575246094	0.958993761316537	0.999999999649628
GO:0003724	RNA helicase activity	2/1183	77/18639	0.025974025974026	0.409239112535816	0.960387339183478	0.999999999649628
GO:0008186	ATP-dependent activity, acting on RNA	2/1183	79/18639	0.0253164556962025	0.39887862867415	0.964514926164031	0.999999999649628
GO:0015370	solute:sodium symporter activity	2/1183	79/18639	0.0253164556962025	0.39887862867415	0.964514926164031	0.999999999649628
GO:0016597	amino acid binding	1/1183	51/18639	0.0196078431372549	0.30893540848292	0.964875408102048	0.999999999649628
GO:0019842	vitamin binding	5/1183	150/18639	0.0333333333333333	0.525190194420964	0.965135971937624	0.999999999649628
GO:0061659	ubiquitin-like protein ligase activity	16/1183	372/18639	0.043010752688172	0.677664766994792	0.96541239421463	0.999999999649628
GO:0005544	calcium-dependent phospholipid binding	1/1183	53/18639	0.0188679245283019	0.297277468540168	0.969204133627254	0.999999999649628
GO:0034212	protein N-acetyltransferase activity	1/1183	53/18639	0.0188679245283019	0.297277468540168	0.969204133627254	0.999999999649628
GO:0005506	iron ion binding	5/1183	154/18639	0.0324675324675325	0.51154889066977	0.970574908424863	0.999999999649628
GO:0017069	snRNA binding	1/1183	54/18639	0.0185185185185185	0.291772330233869	0.971164292344512	0.999999999649628
GO:0008374	O-acyltransferase activity	1/1183	55/18639	0.0181818181818182	0.286467378775071	0.972999785600172	0.999999999649628
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	9/1183	243/18639	0.037037037037037	0.583544660467737	0.974416637485125	0.999999999649628
GO:0030170	pyridoxal phosphate binding	1/1183	56/18639	0.0178571428571429	0.281351889868373	0.974718535795771	0.999999999649628
GO:0050660	flavin adenine dinucleotide binding	2/1183	86/18639	0.0232558139534884	0.36641176354951	0.975943486680297	0.999999999649628
GO:0004676	3-phosphoinositide-dependent protein kinase activity	9/1183	245/18639	0.036734693877551	0.578781030586368	0.976182381036612	0.999999999649628
GO:0004711	ribosomal protein S6 kinase activity	9/1183	245/18639	0.036734693877551	0.578781030586368	0.976182381036612	0.999999999649628
GO:0035175	histone H3S10 kinase activity	9/1183	245/18639	0.036734693877551	0.578781030586368	0.976182381036612	0.999999999649628
GO:0035979	histone H2AXS139 kinase activity	9/1183	245/18639	0.036734693877551	0.578781030586368	0.976182381036612	0.999999999649628
GO:0044022	histone H3S28 kinase activity	9/1183	245/18639	0.036734693877551	0.578781030586368	0.976182381036612	0.999999999649628
GO:0044023	histone H4S1 kinase activity	9/1183	245/18639	0.036734693877551	0.578781030586368	0.976182381036612	0.999999999649628
GO:0044024	histone H2AS1 kinase activity	9/1183	245/18639	0.036734693877551	0.578781030586368	0.976182381036612	0.999999999649628
GO:0044025	histone H2BS14 kinase activity	9/1183	245/18639	0.036734693877551	0.578781030586368	0.976182381036612	0.999999999649628
GO:0072354	histone H3T3 kinase activity	9/1183	245/18639	0.036734693877551	0.578781030586368	0.976182381036612	0.999999999649628
GO:0072371	histone H2AS121 kinase activity	9/1183	245/18639	0.036734693877551	0.578781030586368	0.976182381036612	0.999999999649628
GO:0072518	Rho-dependent protein serine/threonine kinase activity	9/1183	245/18639	0.036734693877551	0.578781030586368	0.976182381036612	0.999999999649628
GO:0140823	histone H2BS36 kinase activity	9/1183	245/18639	0.036734693877551	0.578781030586368	0.976182381036612	0.999999999649628
GO:0140855	histone H3S57 kinase activity	9/1183	245/18639	0.036734693877551	0.578781030586368	0.976182381036612	0.999999999649628
GO:0140995	histone H2A kinase activity	9/1183	245/18639	0.036734693877551	0.578781030586368	0.976182381036612	0.999999999649628
GO:0140997	histone H4 kinase activity	9/1183	245/18639	0.036734693877551	0.578781030586368	0.976182381036612	0.999999999649628
GO:0140998	histone H2B kinase activity	9/1183	245/18639	0.036734693877551	0.578781030586368	0.976182381036612	0.999999999649628
GO:1990244	histone H2AT120 kinase activity	9/1183	245/18639	0.036734693877551	0.578781030586368	0.976182381036612	0.999999999649628
GO:0070279	vitamin B6 binding	1/1183	57/18639	0.0175438596491228	0.276415891800507	0.976327962269085	0.999999999649628
GO:0004677	DNA-dependent protein kinase activity	9/1183	246/18639	0.0365853658536585	0.57642826216935	0.977022871516378	0.999999999649628
GO:0140857	histone H3T45 kinase activity	9/1183	246/18639	0.0365853658536585	0.57642826216935	0.977022871516378	0.999999999649628
GO:0035402	histone H3T11 kinase activity	9/1183	247/18639	0.0364372469635627	0.574094544508746	0.977836163148263	0.999999999649628
GO:0004679	AMP-activated protein kinase activity	9/1183	248/18639	0.0362903225806452	0.571779647151856	0.978623026106574	0.999999999649628
GO:0031593	polyubiquitin modification-dependent protein binding	1/1183	59/18639	0.0169491525423729	0.267045861569982	0.979246195569446	0.999999999649628
GO:0036002	pre-mRNA binding	1/1183	59/18639	0.0169491525423729	0.267045861569982	0.979246195569446	0.999999999649628
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	1/1183	60/18639	0.0166666666666667	0.262595097210482	0.980567603031306	0.999999999649628
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/1183	60/18639	0.0166666666666667	0.262595097210482	0.980567603031306	0.999999999649628
GO:0061630	ubiquitin protein ligase activity	14/1183	353/18639	0.0396600566572238	0.624872185996614	0.980936219545095	0.999999999649628
GO:0016410	N-acyltransferase activity	2/1183	94/18639	0.0212765957446809	0.335227783672956	0.98466613439263	0.999999999649628
GO:0008173	RNA methyltransferase activity	1/1183	67/18639	0.0149253731343284	0.2351597885467	0.987740226879291	0.999999999649628
GO:0005249	voltage-gated potassium channel activity	2/1183	98/18639	0.0204081632653061	0.321545016992427	0.987784299260977	0.999999999649628
GO:0019783	ubiquitin-like protein peptidase activity	3/1183	127/18639	0.0236220472440945	0.372182027542415	0.988985435113738	0.999999999649628
GO:0016755	aminoacyltransferase activity	20/1183	496/18639	0.0403225806451613	0.635310719057617	0.990950155171021	0.999999999649628
GO:0019787	ubiquitin-like protein transferase activity	19/1183	479/18639	0.0396659707724426	0.624965367056262	0.991656610907422	0.999999999649628
GO:0003684	damaged DNA binding	1/1183	74/18639	0.0135135135135135	0.212914943684174	0.992266776817655	0.999999999649628
GO:0004497	monooxygenase activity	2/1183	106/18639	0.0188679245283019	0.297277468540168	0.992277252420984	0.999999999649628
GO:0140101	catalytic activity, acting on a tRNA	3/1183	139/18639	0.0215827338129496	0.340051205020768	0.994133687615018	0.999999999649628
GO:0140767	enzyme-substrate adaptor activity	3/1183	139/18639	0.0215827338129496	0.340051205020768	0.994133687615018	0.999999999649628
GO:0008194	UDP-glycosyltransferase activity	3/1183	145/18639	0.0206896551724138	0.325980120675081	0.995739250041936	0.999999999649628
GO:0016758	hexosyltransferase activity	5/1183	197/18639	0.0253807106598985	0.399891010980429	0.995784010652328	0.999999999649628
GO:0140030	modification-dependent protein binding	4/1183	173/18639	0.023121387283237	0.364293776476969	0.996034758039	0.999999999649628
GO:0032182	ubiquitin-like protein binding	2/1183	120/18639	0.0166666666666667	0.262595097210482	0.996575761569987	0.999999999649628
GO:0000510	H3-H4 histone complex chaperone activity	3/1183	151/18639	0.0198675496688742	0.313027268197925	0.99691433184785	0.999999999649628
GO:0140584	chromatin extrusion motor activity	3/1183	151/18639	0.0198675496688742	0.313027268197925	0.99691433184785	0.999999999649628
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	3/1183	151/18639	0.0198675496688742	0.313027268197925	0.99691433184785	0.999999999649628
GO:0140849	ATP-dependent H2AZ histone chaperone activity	3/1183	151/18639	0.0198675496688742	0.313027268197925	0.99691433184785	0.999999999649628
GO:0004842	ubiquitin-protein transferase activity	16/1183	449/18639	0.0356347438752784	0.561450541919961	0.996918529516423	0.999999999649628
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	2/1183	122/18639	0.0163934426229508	0.258290259551294	0.996954399766718	0.999999999649628
GO:0015616	DNA translocase activity	3/1183	152/18639	0.0197368421052632	0.310967878275571	0.997076677114568	0.999999999649628
GO:0140674	ATP-dependent histone chaperone activity	3/1183	152/18639	0.0197368421052632	0.310967878275571	0.997076677114568	0.999999999649628
GO:0061775	cohesin loader activity	3/1183	153/18639	0.0196078431372549	0.30893540848292	0.997230686544158	0.999999999649628
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	4/1183	181/18639	0.0220994475138122	0.348192394091247	0.997353317464811	0.999999999649628
GO:0031490	chromatin DNA binding	2/1183	128/18639	0.015625	0.246182903634827	0.997859996607884	0.999999999649628
GO:0140658	ATP-dependent chromatin remodeler activity	3/1183	158/18639	0.0189873417721519	0.299158971505612	0.997889538546841	0.999999999649628
GO:0003730	mRNA 3'-UTR binding	7/1183	262/18639	0.0267175572519084	0.42095397262749	0.998020460415751	0.999999999649628
GO:0003689	DNA clamp loader activity	3/1183	160/18639	0.01875	0.295419484361792	0.998107805070669	0.999999999649628
GO:0140597	protein carrier chaperone	4/1183	188/18639	0.0212765957446809	0.335227783672956	0.998149637779763	0.999999999649628
GO:0140713	histone chaperone activity	3/1183	164/18639	0.0182926829268293	0.288214131084675	0.998480185586146	0.999999999649628
GO:0043130	ubiquitin binding	1/1183	100/18639	0.01	0.157557058326289	0.998605664742792	0.999999999649628
GO:0016779	nucleotidyltransferase activity	2/1183	136/18639	0.0147058823529412	0.23170155636219	0.99866710254301	0.999999999649628
GO:0004843	cysteine-type deubiquitinase activity	1/1183	108/18639	0.00925925925925926	0.145886165116934	0.999177323325047	0.999999999649628
GO:0101005	deubiquitinase activity	1/1183	115/18639	0.00869565217391304	0.137006137675034	0.999481618473179	0.999999999649628
GO:0004386	helicase activity	2/1183	155/18639	0.0129032258064516	0.203299430098438	0.999572088039489	0.999999999649628
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	4/1183	229/18639	0.0174672489082969	0.275208835504435	0.999787321602536	0.999999999649628
GO:0140098	catalytic activity, acting on RNA	10/1183	387/18639	0.0258397932816537	0.407124181721677	0.99981244161114	0.999999999649628
GO:0008094	ATP-dependent activity, acting on DNA	3/1183	210/18639	0.0142857142857143	0.225081511894699	0.999885539944837	0.999999999649628
GO:0042393	histone binding	3/1183	247/18639	0.0121457489878543	0.191364848169582	0.999986650787227	0.999999999649628
GO:0045182	translation regulator activity	6/1183	356/18639	0.0168539325842697	0.265545603920712	0.999994782770015	0.999999999649628
GO:0140097	catalytic activity, acting on DNA	5/1183	336/18639	0.0148809523809524	0.234459908223644	0.999996887441771	0.999999999649628
GO:0030371	translation repressor activity	1/1183	329/18639	0.00303951367781155	0.0478896833818508	0.999999999649628	0.999999999649628