ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 30/844 175/18639 0.171428571428571 3.78584969532837 2.87934049762832e-10 1.97351782169803e-07 GO:0019838 growth factor binding 26/844 136/18639 0.191176470588235 4.2219647337608 3.85076648136201e-10 1.97351782169803e-07 GO:0005178 integrin binding 28/844 161/18639 0.173913043478261 3.84071708221718 8.02853126560695e-10 2.74308151574904e-07 GO:0045296 cadherin binding 42/844 334/18639 0.125748502994012 2.77704543519596 2.10344700592018e-09 5.39008295267046e-07 GO:0019199 transmembrane receptor protein kinase activity 18/844 78/18639 0.230769230769231 5.09633612832665 8.75738442940744e-09 1.79526380802853e-06 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 18/844 91/18639 0.197802197802198 4.36828810999427 1.11757211473735e-07 1.90918569600965e-05 GO:0003779 actin binding 46/844 443/18639 0.103837471783296 2.29315952200101 1.440817789071e-07 2.10976890542539e-05 GO:0050840 extracellular matrix binding 15/844 67/18639 0.223880597014925 4.94420669166018 2.32514590357515e-07 2.97909318895566e-05 GO:0001618 virus receptor activity 16/844 81/18639 0.197530864197531 4.36229594523433 5.74864359941936e-07 6.54706632156094e-05 GO:0140272 exogenous protein binding 16/844 82/18639 0.195121951219512 4.30909721419489 6.84583285103865e-07 7.01697867231461e-05 GO:0015291 secondary active transmembrane transporter activity 33/844 287/18639 0.114982578397213 2.53928942979342 8.96263662601605e-07 8.35154776515132e-05 GO:0016798 hydrolase activity, acting on glycosyl bonds 20/844 130/18639 0.153846153846154 3.39755741888443 1.5783225685576e-06 0.000134815052730961 GO:0005201 extracellular matrix structural constituent 23/844 168/18639 0.136904761904762 3.02342163168585 2.15621991419984e-06 0.000170009647081142 GO:0008375 acetylglucosaminyltransferase activity 11/844 43/18639 0.255813953488372 5.64942687093574 2.33662237845047e-06 0.000171065478324544 GO:0005516 calmodulin binding 26/844 207/18639 0.1256038647343 2.77385122604575 2.50339724377381e-06 0.000171065478324544 GO:1901681 sulfur compound binding 31/844 275/18639 0.112727272727273 2.4894829814735 2.90010008574794e-06 0.000174965022560224 GO:0015101 organic cation transmembrane transporter activity 15/844 81/18639 0.185185185185185 4.08965244865719 3.03103301272253e-06 0.000174965022560224 GO:0016758 hexosyltransferase activity 25/844 197/18639 0.126903553299492 2.80255370847066 3.22476498553704e-06 0.000174965022560224 GO:0008201 heparin binding 23/844 172/18639 0.133720930232558 2.95310950071641 3.2432540767261e-06 0.000174965022560224 GO:0016757 glycosyltransferase activity 30/844 267/18639 0.112359550561798 2.48136215985942 4.46250754570744e-06 0.000228703511717506 GO:0022804 active transmembrane transporter activity 43/844 457/18639 0.0940919037199125 2.07793719601356 4.9599583992717e-06 0.0002420932075835 GO:0005539 glycosaminoglycan binding 28/844 242/18639 0.115702479338843 2.55518781089656 5.26418352183144e-06 0.00024526309590351 GO:0038024 cargo receptor activity 13/844 65/18639 0.2 4.41682464454976 5.66390978353484e-06 0.000252413370787966 GO:0017154 semaphorin receptor activity 6/844 13/18639 0.461538461538462 10.1926722566533 1.10517872150661e-05 0.000472003412310114 GO:0004714 transmembrane receptor protein tyrosine kinase activity 12/844 60/18639 0.2 4.41682464454976 1.29273079388748e-05 0.000530019625493869 GO:0005518 collagen binding 13/844 72/18639 0.180555555555556 3.98741113744076 1.82504977960662e-05 0.000719490778498765 GO:0008194 UDP-glycosyltransferase activity 19/844 145/18639 0.131034482758621 2.89378166367053 3.0355325097869e-05 0.00114935755184347 GO:0043236 laminin binding 8/844 29/18639 0.275862068965517 6.09217192351691 3.13970843430411e-05 0.00114935755184347 GO:0015924 mannosyl-oligosaccharide mannosidase activity 5/844 10/18639 0.5 11.0420616113744 3.91937236167228e-05 0.00138529540369451 GO:0005024 transforming growth factor beta receptor activity 6/844 16/18639 0.375 8.28154620853081 4.58732694991887e-05 0.00151677745924737 GO:0015923 mannosidase activity 6/844 16/18639 0.375 8.28154620853081 4.58732694991887e-05 0.00151677745924737 GO:0070325 lipoprotein particle receptor binding 8/844 31/18639 0.258064516129032 5.6991285736126 5.32430225932388e-05 0.00170544056743968 GO:0008514 organic anion transmembrane transporter activity 27/844 269/18639 0.100371747211896 2.2166220335101 9.61160973630131e-05 0.00296555496659219 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 6/844 18/18639 0.333333333333333 7.36137440758294 9.83696281601313e-05 0.00296555496659219 GO:0050750 low-density lipoprotein particle receptor binding 7/844 26/18639 0.269230769230769 5.94572548304776 0.00011754527838408 0.00344239743839093 GO:0005520 insulin-like growth factor binding 6/844 19/18639 0.315789473684211 6.9739336492891 0.000138283582712176 0.00393724089666613 GO:0031994 insulin-like growth factor I binding 5/844 13/18639 0.384615384615385 8.49389354721108 0.000178607930202125 0.00469418278095327 GO:0070123 transforming growth factor beta receptor activity, type III 5/844 13/18639 0.384615384615385 8.49389354721108 0.000178607930202125 0.00469418278095327 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 5/844 13/18639 0.384615384615385 8.49389354721108 0.000178607930202125 0.00469418278095327 GO:0015294 solute:monoatomic cation symporter activity 15/844 116/18639 0.129310344827586 2.85570558914855 0.00023519583472527 0.00602689326483506 GO:0005545 1-phosphatidylinositol binding 5/844 14/18639 0.357142857142857 7.88718686526743 0.000267501624658822 0.00668754061647056 GO:0019955 cytokine binding 17/844 144/18639 0.118055555555556 2.60715343601896 0.000283017010312998 0.00690696275168625 GO:0015293 symporter activity 17/844 146/18639 0.116438356164384 2.57143900538856 0.000333551126408773 0.00795092801323238 GO:0030165 PDZ domain binding 12/844 83/18639 0.144578313253012 3.1928852852167 0.000344776407374267 0.00798656369523843 GO:0046943 carboxylic acid transmembrane transporter activity 20/844 188/18639 0.106382978723404 2.34937481093073 0.000350629625644614 0.00798656369523843 GO:0005342 organic acid transmembrane transporter activity 20/844 189/18639 0.105820105820106 2.33694425637554 0.000375855816713411 0.0082501107007138 GO:0004559 alpha-mannosidase activity 5/844 15/18639 0.333333333333333 7.36137440758294 0.000386346647448061 0.0082501107007138 GO:0015929 hexosaminidase activity 5/844 15/18639 0.333333333333333 7.36137440758294 0.000386346647448061 0.0082501107007138 GO:0005021 vascular endothelial growth factor receptor activity 9/844 51/18639 0.176470588235294 3.8971982157792 0.000420945521005028 0.0088054930414317 GO:0005158 insulin receptor binding 6/844 23/18639 0.260869565217391 5.76107562332578 0.000440485779938858 0.00885290047916332 GO:0017134 fibroblast growth factor binding 6/844 23/18639 0.260869565217391 5.76107562332578 0.000440485779938858 0.00885290047916332 GO:0140327 flippase activity 5/844 16/18639 0.3125 6.901288507109 0.000541107273788457 0.0106660568390994 GO:0048027 mRNA 5'-UTR binding 6/844 24/18639 0.25 5.5210308056872 0.000564997753104442 0.0107244943876306 GO:0050431 transforming growth factor beta binding 6/844 24/18639 0.25 5.5210308056872 0.000564997753104442 0.0107244943876306 GO:0090482 vitamin transmembrane transporter activity 7/844 34/18639 0.205882352941176 4.5467312517424 0.000700865763744917 0.013061589233428 GO:0140303 intramembrane lipid transporter activity 8/844 45/18639 0.177777777777778 3.9260663507109 0.000830335141861385 0.0151980985787128 GO:0002162 dystroglycan binding 4/844 11/18639 0.363636363636364 8.03059026281775 0.00106687030360147 0.018854173468819 GO:0097493 structural molecule activity conferring elasticity 4/844 11/18639 0.363636363636364 8.03059026281775 0.00106687030360147 0.018854173468819 GO:0005044 scavenger receptor activity 6/844 27/18639 0.222222222222222 4.90758293838863 0.00110648112932343 0.0189023859592753 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 6/844 27/18639 0.222222222222222 4.90758293838863 0.00110648112932343 0.0189023859592753 GO:0031267 small GTPase binding 25/844 283/18639 0.088339222614841 1.95089427762799 0.00114817860247044 0.0192931650415115 GO:0051020 GTPase binding 27/844 315/18639 0.0857142857142857 1.89292484766418 0.00116756925928561 0.0193025563027056 GO:0015297 antiporter activity 15/844 135/18639 0.111111111111111 2.45379146919431 0.00118805629357635 0.0193294873161231 GO:0051015 actin filament binding 20/844 209/18639 0.0956937799043062 2.1133132270573 0.00133671873118799 0.0214083859291827 GO:0046873 metal ion transmembrane transporter activity 35/844 450/18639 0.0777777777777778 1.71765402843602 0.00135829227767674 0.0214192243787486 GO:0005025 transforming growth factor beta receptor activity, type I 4/844 12/18639 0.333333333333333 7.36137440758294 0.00154322382549096 0.0222789355088483 GO:0005026 transforming growth factor beta receptor activity, type II 4/844 12/18639 0.333333333333333 7.36137440758294 0.00154322382549096 0.0222789355088483 GO:0016361 activin receptor activity, type I 4/844 12/18639 0.333333333333333 7.36137440758294 0.00154322382549096 0.0222789355088483 GO:0016362 activin receptor activity, type II 4/844 12/18639 0.333333333333333 7.36137440758294 0.00154322382549096 0.0222789355088483 GO:0017002 activin receptor activity 4/844 12/18639 0.333333333333333 7.36137440758294 0.00154322382549096 0.0222789355088483 GO:0045295 gamma-catenin binding 4/844 12/18639 0.333333333333333 7.36137440758294 0.00154322382549096 0.0222789355088483 GO:0005006 epidermal growth factor receptor activity 8/844 50/18639 0.16 3.53345971563981 0.00169475569053328 0.0240825109752898 GO:0004713 protein tyrosine kinase activity 15/844 140/18639 0.107142857142857 2.36615605958023 0.00171514468409381 0.0240825109752898 GO:0015179 L-amino acid transmembrane transporter activity 9/844 62/18639 0.145161290322581 3.20575982265709 0.00180197080138599 0.0249597306948735 GO:0005010 insulin-like growth factor receptor activity 8/844 51/18639 0.156862745098039 3.46417619180374 0.00193174362905016 0.0260531213128476 GO:0005030 neurotrophin receptor activity 8/844 51/18639 0.156862745098039 3.46417619180374 0.00193174362905016 0.0260531213128476 GO:0030246 carbohydrate binding 24/844 280/18639 0.0857142857142857 1.89292484766418 0.00213456135910273 0.0284146154945493 GO:0098631 cell adhesion mediator activity 10/844 76/18639 0.131578947368421 2.90580568720379 0.00218721826066544 0.0287422912459241 GO:0005003 ephrin receptor activity 8/844 53/18639 0.150943396226415 3.33345256192435 0.002483589352429 0.0318209885779965 GO:0005005 transmembrane-ephrin receptor activity 8/844 53/18639 0.150943396226415 3.33345256192435 0.002483589352429 0.0318209885779965 GO:0015926 glucosidase activity 4/844 14/18639 0.285714285714286 6.30974949221395 0.00290260704067019 0.0361092969922286 GO:0098821 BMP receptor activity 4/844 14/18639 0.285714285714286 6.30974949221395 0.00290260704067019 0.0361092969922286 GO:0015370 solute:sodium symporter activity 10/844 79/18639 0.126582278481013 2.79545863579099 0.00292397234180973 0.0361092969922286 GO:0005319 lipid transporter activity 17/844 178/18639 0.0955056179775281 2.1091578358805 0.00303018154944982 0.0366818683085119 GO:0008013 beta-catenin binding 12/844 106/18639 0.113207547169811 2.50008942144326 0.00304191103046196 0.0366818683085119 GO:0016500 protein-hormone receptor activity 9/844 67/18639 0.134328358208955 2.96652401499611 0.00310781275112935 0.0370407915105533 GO:0140103 catalytic activity, acting on a glycoprotein 5/844 23/18639 0.217391304347826 4.80089635277148 0.00320319721313374 0.0377388177409435 GO:0015103 inorganic anion transmembrane transporter activity 16/844 165/18639 0.096969696969697 2.1414907367514 0.00340578319057056 0.0396696337538049 GO:0005041 low-density lipoprotein particle receptor activity 4/844 15/18639 0.266666666666667 5.88909952606635 0.00381761082002369 0.0432628210108481 GO:0048531 beta-1,3-galactosyltransferase activity 4/844 15/18639 0.266666666666667 5.88909952606635 0.00381761082002369 0.0432628210108481 GO:0046915 transition metal ion transmembrane transporter activity 7/844 45/18639 0.155555555555556 3.43530805687204 0.00384089435315822 0.0432628210108481 GO:0030215 semaphorin receptor binding 5/844 24/18639 0.208333333333333 4.60085900473934 0.00389746022893093 0.0434227905940674 GO:0033218 amide binding 21/844 247/18639 0.0850202429149798 1.87759752096245 0.00430165238133485 0.0474106848480454 GO:0070006 metalloaminopeptidase activity 5/844 26/18639 0.192307692307692 4.24694677360554 0.00559743954261075 0.0595954160205441 GO:0043394 proteoglycan binding 6/844 37/18639 0.162162162162162 3.58120917125656 0.0059178275866823 0.0595954160205441 GO:0015026 coreceptor activity 8/844 61/18639 0.131147540983607 2.89627845544247 0.0060130054709254 0.0595954160205441 GO:0048029 monosaccharide binding 9/844 74/18639 0.121621621621622 2.68590687844242 0.00607291859173206 0.0595954160205441 GO:0005004 GPI-linked ephrin receptor activity 7/844 49/18639 0.142857142857143 3.15487474610697 0.00622118001385192 0.0595954160205441 GO:0005008 hepatocyte growth factor receptor activity 7/844 49/18639 0.142857142857143 3.15487474610697 0.00622118001385192 0.0595954160205441 GO:0005009 insulin receptor activity 7/844 49/18639 0.142857142857143 3.15487474610697 0.00622118001385192 0.0595954160205441 GO:0005011 macrophage colony-stimulating factor receptor activity 7/844 49/18639 0.142857142857143 3.15487474610697 0.00622118001385192 0.0595954160205441 GO:0005018 platelet-derived growth factor alpha-receptor activity 7/844 49/18639 0.142857142857143 3.15487474610697 0.00622118001385192 0.0595954160205441 GO:0005020 stem cell factor receptor activity 7/844 49/18639 0.142857142857143 3.15487474610697 0.00622118001385192 0.0595954160205441 GO:0008288 boss receptor activity 7/844 49/18639 0.142857142857143 3.15487474610697 0.00622118001385192 0.0595954160205441 GO:0036332 placental growth factor receptor activity 7/844 49/18639 0.142857142857143 3.15487474610697 0.00622118001385192 0.0595954160205441 GO:0038062 protein tyrosine kinase collagen receptor activity 7/844 49/18639 0.142857142857143 3.15487474610697 0.00622118001385192 0.0595954160205441 GO:0060175 brain-derived neurotrophic factor receptor activity 7/844 49/18639 0.142857142857143 3.15487474610697 0.00622118001385192 0.0595954160205441 GO:0005543 phospholipid binding 35/844 497/18639 0.0704225352112676 1.555219945264 0.00668168748236857 0.0634141636058128 GO:0005007 fibroblast growth factor receptor activity 7/844 50/18639 0.14 3.09177725118483 0.00695803978741542 0.0642521692081153 GO:0005017 platelet-derived growth factor receptor activity 7/844 50/18639 0.14 3.09177725118483 0.00695803978741542 0.0642521692081153 GO:0005019 platelet-derived growth factor beta-receptor activity 7/844 50/18639 0.14 3.09177725118483 0.00695803978741542 0.0642521692081153 GO:0030228 lipoprotein particle receptor activity 4/844 18/18639 0.222222222222222 4.90758293838863 0.00768167499476221 0.0693999528290857 GO:0034185 apolipoprotein binding 4/844 18/18639 0.222222222222222 4.90758293838863 0.00768167499476221 0.0693999528290857 GO:0045499 chemorepellent activity 5/844 28/18639 0.178571428571429 3.94359343263372 0.00776228039631058 0.0693999528290857 GO:0008509 monoatomic anion transmembrane transporter activity 14/844 149/18639 0.0939597315436242 2.07501828938579 0.00778633617106815 0.0693999528290857 GO:0019842 vitamin binding 14/844 150/18639 0.0933333333333333 2.06118483412322 0.00824182146197502 0.0728264396424517 GO:0004177 aminopeptidase activity 6/844 40/18639 0.15 3.31261848341232 0.0087137147296868 0.0759232327932422 GO:0015658 branched-chain amino acid transmembrane transporter activity 3/844 10/18639 0.3 6.62523696682464 0.0087404307020513 0.0759232327932422 GO:0030695 GTPase regulator activity 34/844 489/18639 0.0695296523517382 1.53550141017067 0.00894461457345231 0.0769741676418775 GO:0060589 nucleoside-triphosphatase regulator activity 34/844 490/18639 0.0693877551020408 1.53236773382339 0.00920962468356334 0.0769741676418775 GO:0046332 SMAD binding 9/844 79/18639 0.113924050632911 2.51591277221189 0.0092672169200709 0.0769741676418775 GO:0003756 protein disulfide isomerase activity 4/844 19/18639 0.210526315789474 4.64928909952607 0.00938709361486311 0.0769741676418775 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 4/844 19/18639 0.210526315789474 4.64928909952607 0.00938709361486311 0.0769741676418775 GO:0030506 ankyrin binding 4/844 19/18639 0.210526315789474 4.64928909952607 0.00938709361486311 0.0769741676418775 GO:0042577 lipid phosphatase activity 4/844 19/18639 0.210526315789474 4.64928909952607 0.00938709361486311 0.0769741676418775 GO:0038064 collagen receptor activity 7/844 53/18639 0.132075471698113 2.91677099168381 0.00955740374710426 0.077136526305369 GO:1901505 carbohydrate derivative transmembrane transporter activity 7/844 53/18639 0.132075471698113 2.91677099168381 0.00955740374710426 0.077136526305369 GO:0015175 neutral L-amino acid transmembrane transporter activity 6/844 41/18639 0.146341463414634 3.23182291064617 0.00982606818412285 0.0786853116306713 GO:0001968 fibronectin binding 5/844 30/18639 0.166666666666667 3.68068720379147 0.0104489413296178 0.0830245338206069 GO:0015485 cholesterol binding 7/844 54/18639 0.12962962962963 2.86275671406003 0.0105635052531997 0.083289176034844 GO:0005326 neurotransmitter transmembrane transporter activity 4/844 20/18639 0.2 4.41682464454976 0.0113209165144418 0.0879086320250219 GO:0031418 L-ascorbic acid binding 4/844 20/18639 0.2 4.41682464454976 0.0113209165144418 0.0879086320250219 GO:0032934 sterol binding 8/844 68/18639 0.117647058823529 2.5981321438528 0.0114597451965467 0.0882108610944944 GO:0048185 activin binding 3/844 11/18639 0.272727272727273 6.02294269711331 0.01161801585147 0.0882108610944944 GO:0050998 nitric-oxide synthase binding 3/844 11/18639 0.272727272727273 6.02294269711331 0.01161801585147 0.0882108610944944 GO:0072349 modified amino acid transmembrane transporter activity 5/844 31/18639 0.161290322580645 3.56195535850787 0.0120046889625226 0.0904765160778355 GO:0008378 galactosyltransferase activity 5/844 32/18639 0.15625 3.4506442535545 0.0137103800041327 0.101498918497498 GO:0042910 xenobiotic transmembrane transporter activity 5/844 32/18639 0.15625 3.4506442535545 0.0137103800041327 0.101498918497498 GO:0043014 alpha-tubulin binding 6/844 44/18639 0.136363636363636 3.01147134855666 0.0137642435816119 0.101498918497498 GO:0004300 enoyl-CoA hydratase activity 3/844 12/18639 0.25 5.5210308056872 0.0149762798601297 0.105866805907813 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 3/844 12/18639 0.25 5.5210308056872 0.0149762798601297 0.105866805907813 GO:0008504 monoamine transmembrane transporter activity 3/844 12/18639 0.25 5.5210308056872 0.0149762798601297 0.105866805907813 GO:0017166 vinculin binding 3/844 12/18639 0.25 5.5210308056872 0.0149762798601297 0.105866805907813 GO:0031543 peptidyl-proline dioxygenase activity 3/844 12/18639 0.25 5.5210308056872 0.0149762798601297 0.105866805907813 GO:0097371 MDM2/MDM4 family protein binding 3/844 12/18639 0.25 5.5210308056872 0.0149762798601297 0.105866805907813 GO:0015377 chloride:monoatomic cation symporter activity 4/844 22/18639 0.181818181818182 4.01529513140888 0.0159135287731507 0.111721691729311 GO:0030276 clathrin binding 6/844 46/18639 0.130434782608696 2.88053781166289 0.0169310105127711 0.117287829153534 GO:0019209 kinase activator activity 13/844 148/18639 0.0878378378378378 1.93982163443064 0.0170367866829125 0.117287829153534 GO:0008238 exopeptidase activity 10/844 102/18639 0.0980392156862745 2.16511011987733 0.0171640725590538 0.117287829153534 GO:0015171 amino acid transmembrane transporter activity 10/844 102/18639 0.0980392156862745 2.16511011987733 0.0171640725590538 0.117287829153534 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 7/844 60/18639 0.116666666666667 2.57648104265403 0.0182710859834041 0.12402558366218 GO:0035091 phosphatidylinositol binding 21/844 284/18639 0.073943661971831 1.6329809425272 0.0191886936395755 0.129397440661611 GO:0015108 chloride transmembrane transporter activity 11/844 121/18639 0.0909090909090909 2.00764756570444 0.0214168095876163 0.143478626322266 GO:0004190 aspartic-type endopeptidase activity 5/844 36/18639 0.138888888888889 3.06723933649289 0.0221435739613499 0.147384177340154 GO:0031406 carboxylic acid binding 15/844 187/18639 0.0802139037433155 1.77145373444509 0.0231180206034693 0.14980591209419 GO:0042813 Wnt receptor activity 3/844 14/18639 0.214285714285714 4.73231211916046 0.0231665135691589 0.14980591209419 GO:0044548 S100 protein binding 3/844 14/18639 0.214285714285714 4.73231211916046 0.0231665135691589 0.14980591209419 GO:1901474 azole transmembrane transporter activity 3/844 14/18639 0.214285714285714 4.73231211916046 0.0231665135691589 0.14980591209419 GO:0005507 copper ion binding 7/844 63/18639 0.111111111111111 2.45379146919431 0.0233223762111864 0.14980591209419 GO:0043178 alcohol binding 9/844 92/18639 0.0978260869565217 2.16040335874717 0.0233843374976297 0.14980591209419 GO:0005496 steroid binding 10/844 108/18639 0.0925925925925926 2.04482622432859 0.0245710330053111 0.15272742134797 GO:0070001 aspartic-type peptidase activity 5/844 37/18639 0.135135135135135 2.98434097604714 0.0246788468323918 0.15272742134797 GO:0000030 mannosyltransferase activity 4/844 25/18639 0.16 3.53345971563981 0.0247343921402565 0.15272742134797 GO:0015296 monoatomic anion:monoatomic cation symporter activity 4/844 25/18639 0.16 3.53345971563981 0.0247343921402565 0.15272742134797 GO:0015662 P-type ion transporter activity 4/844 25/18639 0.16 3.53345971563981 0.0247343921402565 0.15272742134797 GO:0140358 P-type transmembrane transporter activity 4/844 25/18639 0.16 3.53345971563981 0.0247343921402565 0.15272742134797 GO:0043177 organic acid binding 15/844 189/18639 0.0793650793650794 1.75270819228165 0.0251421058052714 0.154315320062295 GO:0042562 hormone binding 9/844 94/18639 0.0957446808510638 2.11443732983765 0.026463131914498 0.161456608406907 GO:0016597 amino acid binding 6/844 51/18639 0.117647058823529 2.5981321438528 0.0269545249048025 0.16348158596108 GO:0042887 amide transmembrane transporter activity 5/844 38/18639 0.131578947368421 2.90580568720379 0.0273932175978482 0.165164988457614 GO:0004867 serine-type endopeptidase inhibitor activity 9/844 95/18639 0.0947368421052632 2.09218009478673 0.0281052172674067 0.168134790806853 GO:0030507 spectrin binding 4/844 26/18639 0.153846153846154 3.39755741888443 0.0282138380671012 0.168134790806853 GO:0061134 peptidase regulator activity 17/844 226/18639 0.0752212389380531 1.6611951096758 0.0284098841607611 0.16832445817792 GO:0008235 metalloexopeptidase activity 7/844 66/18639 0.106060606060606 2.34225549332184 0.0292611963974745 0.172371990272479 GO:0005324 long-chain fatty acid transmembrane transporter activity 3/844 16/18639 0.1875 4.1407731042654 0.0333331147766752 0.193030749412949 GO:0022858 alanine transmembrane transporter activity 3/844 16/18639 0.1875 4.1407731042654 0.0333331147766752 0.193030749412949 GO:0140328 floppase activity 3/844 16/18639 0.1875 4.1407731042654 0.0333331147766752 0.193030749412949 GO:0005548 phospholipid transporter activity 7/844 68/18639 0.102941176470588 2.2733656258712 0.0337418338421133 0.194299885888574 GO:0015085 calcium ion transmembrane transporter activity 12/844 147/18639 0.0816326530612245 1.80278556920398 0.0350952833482963 0.200964611351976 GO:0015081 sodium ion transmembrane transporter activity 13/844 164/18639 0.0792682926829268 1.75057074326667 0.0357090047943849 0.203342943968025 GO:0097718 disordered domain specific binding 4/844 28/18639 0.142857142857143 3.15487474610697 0.0360041725515037 0.203891032404924 GO:0140318 protein transporter activity 5/844 41/18639 0.121951219512195 2.69318575887181 0.0366427577412064 0.206367179586465 GO:0098632 cell-cell adhesion mediator activity 6/844 55/18639 0.109090909090909 2.40917707884533 0.0373382167577247 0.209134820637529 GO:0004674 protein serine/threonine kinase activity 28/844 433/18639 0.0646651270207852 1.42807263334173 0.0376527083888488 0.209750141840054 GO:0097110 scaffold protein binding 7/844 70/18639 0.1 2.20841232227488 0.0386567066377645 0.212314800097586 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 3/844 17/18639 0.176470588235294 3.8971982157792 0.0391487777740915 0.212314800097586 GO:0008484 sulfuric ester hydrolase activity 3/844 17/18639 0.176470588235294 3.8971982157792 0.0391487777740915 0.212314800097586 GO:0019198 transmembrane receptor protein phosphatase activity 3/844 17/18639 0.176470588235294 3.8971982157792 0.0391487777740915 0.212314800097586 GO:0070403 NAD+ binding 3/844 17/18639 0.176470588235294 3.8971982157792 0.0391487777740915 0.212314800097586 GO:0005096 GTPase activator activity 19/844 271/18639 0.0701107011070111 1.54833336248054 0.0398606395976114 0.215037660987114 GO:0048487 beta-tubulin binding 5/844 42/18639 0.119047619047619 2.62906228842248 0.040103153001989 0.215213255638946 GO:0035250 UDP-galactosyltransferase activity 4/844 29/18639 0.137931034482759 3.04608596175846 0.0403189254652853 0.215244263551653 GO:0051087 protein-folding chaperone binding 11/844 134/18639 0.082089552238806 1.81287578694207 0.04101068337991 0.21780285214719 GO:1901981 phosphatidylinositol phosphate binding 14/844 185/18639 0.0756756756756757 1.6712309465864 0.041991003587379 0.221859683902389 GO:0015932 nucleobase-containing compound transmembrane transporter activity 6/844 57/18639 0.105263157894737 2.32464454976303 0.0433695332845463 0.227968059572615 GO:0008525 phosphatidylcholine transporter activity 3/844 18/18639 0.166666666666667 3.68068720379147 0.0454421983299573 0.236437833950286 GO:0070064 proline-rich region binding 3/844 18/18639 0.166666666666667 3.68068720379147 0.0454421983299573 0.236437833950286 GO:0030020 extracellular matrix structural constituent conferring tensile strength 5/844 44/18639 0.113636363636364 2.50955945713055 0.047600253282372 0.246415452598138 GO:0051082 unfolded protein binding 10/844 121/18639 0.0826446280991736 1.8251341506404 0.0479946810908808 0.247208784513331 GO:0017147 Wnt-protein binding 4/844 31/18639 0.129032258064516 2.8495642868063 0.049789806703334 0.255172759354587 GO:0030295 protein kinase activator activity 11/844 139/18639 0.079136690647482 1.74766442769955 0.0510919568139234 0.260543560867022 GO:0008381 mechanosensitive monoatomic ion channel activity 3/844 19/18639 0.157894736842105 3.48696682464455 0.0522025304640375 0.261012652320188 GO:0015245 fatty acid transmembrane transporter activity 3/844 19/18639 0.157894736842105 3.48696682464455 0.0522025304640375 0.261012652320188 GO:0043395 heparan sulfate proteoglycan binding 3/844 19/18639 0.157894736842105 3.48696682464455 0.0522025304640375 0.261012652320188 GO:0046624 sphingolipid transporter activity 3/844 19/18639 0.157894736842105 3.48696682464455 0.0522025304640375 0.261012652320188 GO:0072341 modified amino acid binding 8/844 91/18639 0.0879120879120879 1.94146138221968 0.0538827057638494 0.268105696155076 GO:0071813 lipoprotein particle binding 4/844 32/18639 0.125 2.7605154028436 0.0549440105175056 0.269462252538006 GO:0071814 protein-lipid complex binding 4/844 32/18639 0.125 2.7605154028436 0.0549440105175056 0.269462252538006 GO:0120015 sterol transfer activity 4/844 32/18639 0.125 2.7605154028436 0.0549440105175056 0.269462252538006 GO:0015095 magnesium ion transmembrane transporter activity 3/844 20/18639 0.15 3.31261848341232 0.0594169329257309 0.290011220232734 GO:0030296 protein tyrosine kinase activator activity 4/844 33/18639 0.121212121212121 2.67686342093925 0.0603746542561882 0.29328919721608 GO:1901682 sulfur compound transmembrane transporter activity 6/844 63/18639 0.0952380952380952 2.10324983073798 0.0649522925717685 0.31403820700973 GO:0008376 acetylgalactosaminyltransferase activity 4/844 34/18639 0.117647058823529 2.5981321438528 0.0660786690002267 0.31649829778146 GO:0015020 glucuronosyltransferase activity 4/844 34/18639 0.117647058823529 2.5981321438528 0.0660786690002267 0.31649829778146 GO:0015174 basic amino acid transmembrane transporter activity 3/844 21/18639 0.142857142857143 3.15487474610697 0.0670708615269796 0.316809368963844 GO:0036122 BMP binding 3/844 21/18639 0.142857142857143 3.15487474610697 0.0670708615269796 0.316809368963844 GO:0051010 microtubule plus-end binding 3/844 21/18639 0.142857142857143 3.15487474610697 0.0670708615269796 0.316809368963844 GO:0005200 structural constituent of cytoskeleton 9/844 112/18639 0.0803571428571429 1.77461704468517 0.0676610898132095 0.318131270910733 GO:0019787 ubiquitin-like protein transferase activity 29/844 479/18639 0.0605427974947808 1.33703460012467 0.0692514085430165 0.324121889299506 GO:0005343 organic acid:sodium symporter activity 4/844 35/18639 0.114285714285714 2.52389979688558 0.0720522313370018 0.32551009402029 GO:0005337 nucleoside transmembrane transporter activity 2/844 10/18639 0.2 4.41682464454976 0.0724061477430498 0.32551009402029 GO:0005345 purine nucleobase transmembrane transporter activity 2/844 10/18639 0.2 4.41682464454976 0.0724061477430498 0.32551009402029 GO:0005381 iron ion transmembrane transporter activity 2/844 10/18639 0.2 4.41682464454976 0.0724061477430498 0.32551009402029 GO:0008239 dipeptidyl-peptidase activity 2/844 10/18639 0.2 4.41682464454976 0.0724061477430498 0.32551009402029 GO:0015187 glycine transmembrane transporter activity 2/844 10/18639 0.2 4.41682464454976 0.0724061477430498 0.32551009402029 GO:0015643 toxic substance binding 2/844 10/18639 0.2 4.41682464454976 0.0724061477430498 0.32551009402029 GO:0031419 cobalamin binding 2/844 10/18639 0.2 4.41682464454976 0.0724061477430498 0.32551009402029 GO:0031957 very long-chain fatty acid-CoA ligase activity 2/844 10/18639 0.2 4.41682464454976 0.0724061477430498 0.32551009402029 GO:0004175 endopeptidase activity 25/844 405/18639 0.0617283950617284 1.36321748288573 0.0730277045481338 0.326870729964355 GO:0030021 extracellular matrix structural constituent conferring compression resistance 3/844 22/18639 0.136363636363636 3.01147134855666 0.0751483351196894 0.334900189120355 GO:0042626 ATPase-coupled transmembrane transporter activity 8/844 98/18639 0.0816326530612245 1.80278556920398 0.0762771547890529 0.338459236618092 GO:0001540 amyloid-beta binding 7/844 83/18639 0.0843373493975904 1.86251641637641 0.0818301258982767 0.348324963176318 GO:0004842 ubiquitin-protein transferase activity 27/844 449/18639 0.0601336302895323 1.32799850114525 0.0823167804716759 0.348324963176318 GO:0030414 peptidase inhibitor activity 12/844 169/18639 0.0710059171597633 1.56810342410051 0.0826812387047045 0.348324963176318 GO:0008234 cysteine-type peptidase activity 13/844 187/18639 0.0695187165775401 1.53525990318575 0.0830488683450999 0.348324963176318 GO:0005283 amino acid:sodium symporter activity 3/844 23/18639 0.130434782608696 2.88053781166289 0.0836321771803012 0.348324963176318 GO:1990782 protein tyrosine kinase binding 9/844 117/18639 0.0769230769230769 1.69877870944222 0.0838068771717776 0.348324963176318 GO:0005080 protein kinase C binding 5/844 52/18639 0.0961538461538462 2.12347338680277 0.0853092784799629 0.348324963176318 GO:0008046 axon guidance receptor activity 2/844 11/18639 0.181818181818182 4.01529513140888 0.0859146214967342 0.348324963176318 GO:0008172 S-methyltransferase activity 2/844 11/18639 0.181818181818182 4.01529513140888 0.0859146214967342 0.348324963176318 GO:0008271 secondary active sulfate transmembrane transporter activity 2/844 11/18639 0.181818181818182 4.01529513140888 0.0859146214967342 0.348324963176318 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 2/844 11/18639 0.181818181818182 4.01529513140888 0.0859146214967342 0.348324963176318 GO:0015173 aromatic amino acid transmembrane transporter activity 2/844 11/18639 0.181818181818182 4.01529513140888 0.0859146214967342 0.348324963176318 GO:0015205 nucleobase transmembrane transporter activity 2/844 11/18639 0.181818181818182 4.01529513140888 0.0859146214967342 0.348324963176318 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 2/844 11/18639 0.181818181818182 4.01529513140888 0.0859146214967342 0.348324963176318 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 2/844 11/18639 0.181818181818182 4.01529513140888 0.0859146214967342 0.348324963176318 GO:0032050 clathrin heavy chain binding 2/844 11/18639 0.181818181818182 4.01529513140888 0.0859146214967342 0.348324963176318 GO:0032794 GTPase activating protein binding 2/844 11/18639 0.181818181818182 4.01529513140888 0.0859146214967342 0.348324963176318 GO:0035252 UDP-xylosyltransferase activity 2/844 11/18639 0.181818181818182 4.01529513140888 0.0859146214967342 0.348324963176318 GO:0042285 xylosyltransferase activity 2/844 11/18639 0.181818181818182 4.01529513140888 0.0859146214967342 0.348324963176318 GO:0047676 arachidonate-CoA ligase activity 2/844 11/18639 0.181818181818182 4.01529513140888 0.0859146214967342 0.348324963176318 GO:1990948 ubiquitin ligase inhibitor activity 2/844 11/18639 0.181818181818182 4.01529513140888 0.0859146214967342 0.348324963176318 GO:0051117 ATPase binding 7/844 84/18639 0.0833333333333333 1.84034360189573 0.0859767957888862 0.348324963176318 GO:0002020 protease binding 10/844 136/18639 0.0735294117647059 1.623832589908 0.089580116458429 0.36007693870545 GO:0044325 transmembrane transporter binding 10/844 136/18639 0.0735294117647059 1.623832589908 0.089580116458429 0.36007693870545 GO:0016860 intramolecular oxidoreductase activity 5/844 53/18639 0.0943396226415094 2.08340785120272 0.0908756901289592 0.361037141016214 GO:0017046 peptide hormone binding 5/844 53/18639 0.0943396226415094 2.08340785120272 0.0908756901289592 0.361037141016214 GO:0051018 protein kinase A binding 5/844 53/18639 0.0943396226415094 2.08340785120272 0.0908756901289592 0.361037141016214 GO:0005109 frizzled binding 4/844 38/18639 0.105263157894737 2.32464454976303 0.0915417061962172 0.362278953093138 GO:0015149 hexose transmembrane transporter activity 3/844 24/18639 0.125 2.7605154028436 0.0925042348327805 0.36328291457318 GO:0055056 D-glucose transmembrane transporter activity 3/844 24/18639 0.125 2.7605154028436 0.0925042348327805 0.36328291457318 GO:0016755 aminoacyltransferase activity 29/844 496/18639 0.0584677419354839 1.2912088174591 0.0963222726453631 0.3751527728994 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 5/844 54/18639 0.0925925925925926 2.04482622432859 0.0966247141906746 0.3751527728994 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 5/844 54/18639 0.0925925925925926 2.04482622432859 0.0966247141906746 0.3751527728994 GO:0000340 RNA 7-methylguanosine cap binding 2/844 12/18639 0.166666666666667 3.68068720379147 0.100102289824055 0.377859479868035 GO:0005049 nuclear export signal receptor activity 2/844 12/18639 0.166666666666667 3.68068720379147 0.100102289824055 0.377859479868035 GO:0005078 MAP-kinase scaffold activity 2/844 12/18639 0.166666666666667 3.68068720379147 0.100102289824055 0.377859479868035 GO:0005095 GTPase inhibitor activity 2/844 12/18639 0.166666666666667 3.68068720379147 0.100102289824055 0.377859479868035 GO:0005247 voltage-gated chloride channel activity 2/844 12/18639 0.166666666666667 3.68068720379147 0.100102289824055 0.377859479868035 GO:1990247 N6-methyladenosine-containing RNA reader activity 2/844 12/18639 0.166666666666667 3.68068720379147 0.100102289824055 0.377859479868035 GO:0042277 peptide binding 16/844 249/18639 0.0642570281124498 1.41906012676298 0.101475920317293 0.377859479868035 GO:0004709 MAP kinase kinase kinase activity 3/844 25/18639 0.12 2.65009478672986 0.101745577018125 0.377859479868035 GO:0005537 D-mannose binding 3/844 25/18639 0.12 2.65009478672986 0.101745577018125 0.377859479868035 GO:0015645 fatty acid ligase activity 3/844 25/18639 0.12 2.65009478672986 0.101745577018125 0.377859479868035 GO:0120020 cholesterol transfer activity 3/844 25/18639 0.12 2.65009478672986 0.101745577018125 0.377859479868035 GO:0120515 fatty acid-CoA ligase activity 3/844 25/18639 0.12 2.65009478672986 0.101745577018125 0.377859479868035 GO:0004197 cysteine-type endopeptidase activity 7/844 88/18639 0.0795454545454545 1.75669161999138 0.103731692563522 0.383844710749494 GO:0015036 disulfide oxidoreductase activity 4/844 40/18639 0.1 2.20841232227488 0.105782942097224 0.387241127320194 GO:0015144 carbohydrate transmembrane transporter activity 4/844 40/18639 0.1 2.20841232227488 0.105782942097224 0.387241127320194 GO:0140662 ATP-dependent protein folding chaperone 4/844 40/18639 0.1 2.20841232227488 0.105782942097224 0.387241127320194 GO:0005112 Notch binding 3/844 26/18639 0.115384615384615 2.54816806416332 0.111336673403041 0.399354341552103 GO:0005227 calcium-activated cation channel activity 3/844 26/18639 0.115384615384615 2.54816806416332 0.111336673403041 0.399354341552103 GO:0015145 monosaccharide transmembrane transporter activity 3/844 26/18639 0.115384615384615 2.54816806416332 0.111336673403041 0.399354341552103 GO:0043539 protein serine/threonine kinase activator activity 6/844 73/18639 0.0821917808219178 1.8151334155684 0.112598585141664 0.399354341552103 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 4/844 41/18639 0.0975609756097561 2.15454860709745 0.113257556622199 0.399354341552103 GO:0017080 sodium channel regulator activity 4/844 41/18639 0.0975609756097561 2.15454860709745 0.113257556622199 0.399354341552103 GO:0004866 endopeptidase inhibitor activity 11/844 161/18639 0.0683229813664596 1.50885313944247 0.114426983894886 0.399354341552103 GO:0005338 nucleotide-sugar transmembrane transporter activity 2/844 13/18639 0.153846153846154 3.39755741888443 0.11488011563125 0.399354341552103 GO:0005542 folic acid binding 2/844 13/18639 0.153846153846154 3.39755741888443 0.11488011563125 0.399354341552103 GO:0035673 oligopeptide transmembrane transporter activity 2/844 13/18639 0.153846153846154 3.39755741888443 0.11488011563125 0.399354341552103 GO:0043560 insulin receptor substrate binding 2/844 13/18639 0.153846153846154 3.39755741888443 0.11488011563125 0.399354341552103 GO:0051011 microtubule minus-end binding 2/844 13/18639 0.153846153846154 3.39755741888443 0.11488011563125 0.399354341552103 GO:0061459 L-arginine transmembrane transporter activity 2/844 13/18639 0.153846153846154 3.39755741888443 0.11488011563125 0.399354341552103 GO:0140333 glycerophospholipid flippase activity 2/844 13/18639 0.153846153846154 3.39755741888443 0.11488011563125 0.399354341552103 GO:0016504 peptidase activator activity 5/844 57/18639 0.087719298245614 1.93720379146919 0.114936127568654 0.399354341552103 GO:0019903 protein phosphatase binding 10/844 144/18639 0.0694444444444444 1.53361966824645 0.11854416192587 0.410499209371679 GO:0008307 structural constituent of muscle 4/844 42/18639 0.0952380952380952 2.10324983073798 0.120958020161168 0.413346920026676 GO:0035198 miRNA binding 4/844 42/18639 0.0952380952380952 2.10324983073798 0.120958020161168 0.413346920026676 GO:0005385 zinc ion transmembrane transporter activity 3/844 27/18639 0.111111111111111 2.45379146919431 0.121257555512254 0.413346920026676 GO:0016405 CoA-ligase activity 3/844 27/18639 0.111111111111111 2.45379146919431 0.121257555512254 0.413346920026676 GO:0061980 regulatory RNA binding 5/844 58/18639 0.0862068965517241 1.90380372609904 0.121382851637102 0.413346920026676 GO:0044183 protein folding chaperone 6/844 75/18639 0.08 1.76672985781991 0.123807474427268 0.420207487708444 GO:0141003 histone H2AX kinase activity 21/844 354/18639 0.0593220338983051 1.31007510643425 0.126137005119351 0.426701089925196 GO:0051213 dioxygenase activity 7/844 93/18639 0.0752688172043011 1.66224583397034 0.128480949995191 0.42785765239439 GO:0048156 tau protein binding 4/844 43/18639 0.0930232558139535 2.05433704397663 0.12887625277462 0.42785765239439 GO:0004065 arylsulfatase activity 2/844 14/18639 0.142857142857143 3.15487474610697 0.130165715974932 0.42785765239439 GO:0008195 phosphatidate phosphatase activity 2/844 14/18639 0.142857142857143 3.15487474610697 0.130165715974932 0.42785765239439 GO:0031404 chloride ion binding 2/844 14/18639 0.142857142857143 3.15487474610697 0.130165715974932 0.42785765239439 GO:1901612 cardiolipin binding 2/844 14/18639 0.142857142857143 3.15487474610697 0.130165715974932 0.42785765239439 GO:0008237 metallopeptidase activity 12/844 184/18639 0.0652173913043478 1.44026890583144 0.131220842682029 0.42785765239439 GO:0061135 endopeptidase regulator activity 12/844 184/18639 0.0652173913043478 1.44026890583144 0.131220842682029 0.42785765239439 GO:0046875 ephrin receptor binding 3/844 28/18639 0.107142857142857 2.36615605958023 0.131487961467544 0.42785765239439 GO:0046966 nuclear thyroid hormone receptor binding 3/844 28/18639 0.107142857142857 2.36615605958023 0.131487961467544 0.42785765239439 GO:0050698 proteoglycan sulfotransferase activity 3/844 28/18639 0.107142857142857 2.36615605958023 0.131487961467544 0.42785765239439 GO:0051119 sugar transmembrane transporter activity 3/844 28/18639 0.107142857142857 2.36615605958023 0.131487961467544 0.42785765239439 GO:0140996 histone H3 kinase activity 21/844 357/18639 0.0588235294117647 1.2990660719264 0.133902491637939 0.434108175530651 GO:0004857 enzyme inhibitor activity 24/844 416/18639 0.0576923076923077 1.27408403208166 0.134255894286065 0.434108175530651 GO:0005262 calcium channel activity 9/844 131/18639 0.0687022900763359 1.51722983973083 0.140176318821971 0.443709248490954 GO:0019905 syntaxin binding 5/844 61/18639 0.0819672131147541 1.81017403465154 0.141694877127473 0.443709248490954 GO:0035173 histone kinase activity 21/844 360/18639 0.0583333333333333 1.28824052132701 0.141942744916768 0.443709248490954 GO:0003785 actin monomer binding 3/844 29/18639 0.103448275862069 2.28456447131884 0.142007465621651 0.443709248490954 GO:0004629 phospholipase C activity 3/844 29/18639 0.103448275862069 2.28456447131884 0.142007465621651 0.443709248490954 GO:0005416 amino acid:monoatomic cation symporter activity 3/844 29/18639 0.103448275862069 2.28456447131884 0.142007465621651 0.443709248490954 GO:0099604 ligand-gated calcium channel activity 3/844 29/18639 0.103448275862069 2.28456447131884 0.142007465621651 0.443709248490954 GO:0031625 ubiquitin protein ligase binding 18/844 302/18639 0.0596026490066225 1.3162722450645 0.143503856280689 0.443709248490954 GO:0044389 ubiquitin-like protein ligase binding 19/844 322/18639 0.0590062111801242 1.3031004386094 0.145103983783199 0.443709248490954 GO:0000774 adenyl-nucleotide exchange factor activity 2/844 15/18639 0.133333333333333 2.94454976303318 0.145882943162392 0.443709248490954 GO:0004467 long-chain fatty acid-CoA ligase activity 2/844 15/18639 0.133333333333333 2.94454976303318 0.145882943162392 0.443709248490954 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 2/844 15/18639 0.133333333333333 2.94454976303318 0.145882943162392 0.443709248490954 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 2/844 15/18639 0.133333333333333 2.94454976303318 0.145882943162392 0.443709248490954 GO:0005402 carbohydrate:monoatomic cation symporter activity 2/844 15/18639 0.133333333333333 2.94454976303318 0.145882943162392 0.443709248490954 GO:0015116 sulfate transmembrane transporter activity 2/844 15/18639 0.133333333333333 2.94454976303318 0.145882943162392 0.443709248490954 GO:0031386 protein tag activity 2/844 15/18639 0.133333333333333 2.94454976303318 0.145882943162392 0.443709248490954 GO:0042809 nuclear vitamin D receptor binding 2/844 15/18639 0.133333333333333 2.94454976303318 0.145882943162392 0.443709248490954 GO:0055105 ubiquitin-protein transferase inhibitor activity 2/844 15/18639 0.133333333333333 2.94454976303318 0.145882943162392 0.443709248490954 GO:0140776 protein-containing complex destabilizing activity 2/844 15/18639 0.133333333333333 2.94454976303318 0.145882943162392 0.443709248490954 GO:0141047 molecular tag activity 2/844 15/18639 0.133333333333333 2.94454976303318 0.145882943162392 0.443709248490954 GO:0042578 phosphoric ester hydrolase activity 21/844 363/18639 0.0578512396694215 1.27759390544828 0.150254956603458 0.453791165275635 GO:0035401 histone H3Y41 kinase activity 8/844 115/18639 0.0695652173913043 1.53628683288687 0.150525849945089 0.453791165275635 GO:0140801 histone H2AXY142 kinase activity 8/844 115/18639 0.0695652173913043 1.53628683288687 0.150525849945089 0.453791165275635 GO:0022839 monoatomic ion-gated channel activity 3/844 30/18639 0.1 2.20841232227488 0.152795594286279 0.456604910039171 GO:0031210 phosphatidylcholine binding 3/844 30/18639 0.1 2.20841232227488 0.152795594286279 0.456604910039171 GO:0035925 mRNA 3'-UTR AU-rich region binding 3/844 30/18639 0.1 2.20841232227488 0.152795594286279 0.456604910039171 GO:0048306 calcium-dependent protein binding 6/844 80/18639 0.075 1.65630924170616 0.154070980534561 0.459077776302108 GO:0019207 kinase regulator activity 17/844 287/18639 0.0592334494773519 1.30811879716631 0.157461399898802 0.467820101148615 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 2/844 16/18639 0.125 2.7605154028436 0.161961490074637 0.474697324225798 GO:0005159 insulin-like growth factor receptor binding 2/844 16/18639 0.125 2.7605154028436 0.161961490074637 0.474697324225798 GO:0015378 sodium:chloride symporter activity 2/844 16/18639 0.125 2.7605154028436 0.161961490074637 0.474697324225798 GO:0015562 efflux transmembrane transporter activity 2/844 16/18639 0.125 2.7605154028436 0.161961490074637 0.474697324225798 GO:0043495 protein-membrane adaptor activity 4/844 47/18639 0.0851063829787234 1.87949984874458 0.162554888588541 0.474697324225798 GO:0140359 ABC-type transporter activity 4/844 47/18639 0.0851063829787234 1.87949984874458 0.162554888588541 0.474697324225798 GO:0005452 solute:inorganic anion antiporter activity 3/844 31/18639 0.0967741935483871 2.13717321510472 0.163831928670165 0.475715940189574 GO:0016878 acid-thiol ligase activity 3/844 31/18639 0.0967741935483871 2.13717321510472 0.163831928670165 0.475715940189574 GO:0015106 bicarbonate transmembrane transporter activity 3/844 32/18639 0.09375 2.0703865521327 0.175096196065268 0.504139328558708 GO:0022884 macromolecule transmembrane transporter activity 3/844 32/18639 0.09375 2.0703865521327 0.175096196065268 0.504139328558708 GO:0140142 nucleocytoplasmic carrier activity 3/844 32/18639 0.09375 2.0703865521327 0.175096196065268 0.504139328558708 GO:0061659 ubiquitin-like protein ligase activity 21/844 372/18639 0.0564516129032258 1.24668437547776 0.176784639205513 0.506357150528839 GO:0004029 aldehyde dehydrogenase (NAD+) activity 2/844 17/18639 0.117647058823529 2.5981321438528 0.178336518381376 0.506357150528839 GO:0015278 intracellularly gated calcium channel activity 2/844 17/18639 0.117647058823529 2.5981321438528 0.178336518381376 0.506357150528839 GO:0032977 membrane insertase activity 2/844 17/18639 0.117647058823529 2.5981321438528 0.178336518381376 0.506357150528839 GO:0038191 neuropilin binding 2/844 17/18639 0.117647058823529 2.5981321438528 0.178336518381376 0.506357150528839 GO:0016763 pentosyltransferase activity 4/844 49/18639 0.0816326530612245 1.80278556920398 0.180470962449474 0.511002034559975 GO:0003712 transcription coregulator activity 27/844 495/18639 0.0545454545454545 1.20458853942266 0.183444479147955 0.517990609164334 GO:0003713 transcription coactivator activity 15/844 256/18639 0.05859375 1.29399159508294 0.186220864778642 0.523924819184467 GO:0019956 chemokine binding 3/844 33/18639 0.0909090909090909 2.00764756570444 0.186568350246176 0.523924819184467 GO:0015605 organophosphate ester transmembrane transporter activity 4/844 50/18639 0.08 1.76672985781991 0.189665423502102 0.528629672215606 GO:0016853 isomerase activity 11/844 180/18639 0.0611111111111111 1.34958530805687 0.193924199141715 0.528629672215606 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 6/844 86/18639 0.0697674418604651 1.54075278298248 0.194188413955902 0.528629672215606 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 2/844 18/18639 0.111111111111111 2.45379146919431 0.194948308387804 0.528629672215606 GO:0004706 JUN kinase kinase kinase activity 2/844 18/18639 0.111111111111111 2.45379146919431 0.194948308387804 0.528629672215606 GO:0008308 voltage-gated monoatomic anion channel activity 2/844 18/18639 0.111111111111111 2.45379146919431 0.194948308387804 0.528629672215606 GO:0008409 5'-3' exonuclease activity 2/844 18/18639 0.111111111111111 2.45379146919431 0.194948308387804 0.528629672215606 GO:0015172 acidic amino acid transmembrane transporter activity 2/844 18/18639 0.111111111111111 2.45379146919431 0.194948308387804 0.528629672215606 GO:0015373 monoatomic anion:sodium symporter activity 2/844 18/18639 0.111111111111111 2.45379146919431 0.194948308387804 0.528629672215606 GO:0016854 racemase and epimerase activity 2/844 18/18639 0.111111111111111 2.45379146919431 0.194948308387804 0.528629672215606 GO:0017075 syntaxin-1 binding 2/844 18/18639 0.111111111111111 2.45379146919431 0.194948308387804 0.528629672215606 GO:0017128 phospholipid scramblase activity 2/844 18/18639 0.111111111111111 2.45379146919431 0.194948308387804 0.528629672215606 GO:1901611 phosphatidylglycerol binding 2/844 18/18639 0.111111111111111 2.45379146919431 0.194948308387804 0.528629672215606 GO:0015035 protein-disulfide reductase activity 3/844 34/18639 0.0882352941176471 1.9485991078896 0.198228641979655 0.534695679024069 GO:0016831 carboxy-lyase activity 3/844 34/18639 0.0882352941176471 1.9485991078896 0.198228641979655 0.534695679024069 GO:0008081 phosphoric diester hydrolase activity 6/844 87/18639 0.0689655172413793 1.52304298087923 0.201230571123817 0.541368334388222 GO:0106310 protein serine kinase activity 20/844 361/18639 0.0554016620498615 1.22349713145423 0.206144988643634 0.553137731308181 GO:0008028 monocarboxylic acid transmembrane transporter activity 5/844 70/18639 0.0714285714285714 1.57743737305349 0.210242643059085 0.562659814975358 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 2/844 19/18639 0.105263157894737 2.32464454976303 0.211741929320011 0.563728513124706 GO:0042800 histone H3K4 methyltransferase activity 2/844 19/18639 0.105263157894737 2.32464454976303 0.211741929320011 0.563728513124706 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 6/844 89/18639 0.0674157303370786 1.48881729591565 0.215586783599151 0.570998587052014 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 6/844 89/18639 0.0674157303370786 1.48881729591565 0.215586783599151 0.570998587052014 GO:0008146 sulfotransferase activity 4/844 53/18639 0.0754716981132075 1.66672628096217 0.218079691570676 0.576112587267894 GO:0140793 histone H2AXY142 phosphatase activity 6/844 90/18639 0.0666666666666667 1.47227488151659 0.222893139200908 0.587314826943266 GO:0051287 NAD binding 4/844 54/18639 0.0740740740740741 1.63586097946288 0.227796089761076 0.594882238940001 GO:0000339 RNA cap binding 2/844 20/18639 0.1 2.20841232227488 0.228666928919376 0.594882238940001 GO:0001614 purinergic nucleotide receptor activity 2/844 20/18639 0.1 2.20841232227488 0.228666928919376 0.594882238940001 GO:0016502 nucleotide receptor activity 2/844 20/18639 0.1 2.20841232227488 0.228666928919376 0.594882238940001 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/844 20/18639 0.1 2.20841232227488 0.228666928919376 0.594882238940001 GO:0004222 metalloendopeptidase activity 7/844 110/18639 0.0636363636363636 1.40535329599311 0.231065955443954 0.599601529949501 GO:0008374 O-acyltransferase activity 4/844 55/18639 0.0727272727272727 1.60611805256355 0.237619048649477 0.614036215882736 GO:1902936 phosphatidylinositol bisphosphate binding 7/844 111/18639 0.0630630630630631 1.39269245548866 0.237826709956533 0.614036215882736 GO:0019902 phosphatase binding 11/844 190/18639 0.0578947368421053 1.27855450236967 0.243624094725076 0.623528530494258 GO:0005085 guanyl-nucleotide exchange factor activity 13/844 230/18639 0.0565217391304348 1.24823305172059 0.244435636745462 0.623528530494258 GO:0001846 opsonin binding 2/844 21/18639 0.0952380952380952 2.10324983073798 0.245677041276471 0.623528530494258 GO:0009931 calcium-dependent protein serine/threonine kinase activity 2/844 21/18639 0.0952380952380952 2.10324983073798 0.245677041276471 0.623528530494258 GO:0061891 calcium ion sensor activity 2/844 21/18639 0.0952380952380952 2.10324983073798 0.245677041276471 0.623528530494258 GO:0072542 protein phosphatase activator activity 2/844 21/18639 0.0952380952380952 2.10324983073798 0.245677041276471 0.623528530494258 GO:0000146 microfilament motor activity 3/844 38/18639 0.0789473684210526 1.74348341232227 0.246369809609926 0.623528530494258 GO:0043531 ADP binding 3/844 38/18639 0.0789473684210526 1.74348341232227 0.246369809609926 0.623528530494258 GO:0170055 lipid transmembrane transporter activity 4/844 56/18639 0.0714285714285714 1.57743737305349 0.247539101919419 0.624944777013312 GO:0061630 ubiquitin protein ligase activity 19/844 353/18639 0.0538243626062323 1.18866385618195 0.250766768615358 0.631537930788065 GO:0003725 double-stranded RNA binding 5/844 75/18639 0.0666666666666667 1.47227488151659 0.252180974095722 0.633542888353223 GO:0016791 phosphatase activity 15/844 273/18639 0.0549450549450549 1.2134133638873 0.256763321614407 0.643477761992095 GO:0005243 gap junction channel activity 2/844 22/18639 0.0909090909090909 2.00764756570444 0.262729911892149 0.647351345407337 GO:0008093 cytoskeletal anchor activity 2/844 22/18639 0.0909090909090909 2.00764756570444 0.262729911892149 0.647351345407337 GO:0031683 G-protein beta/gamma-subunit complex binding 2/844 22/18639 0.0909090909090909 2.00764756570444 0.262729911892149 0.647351345407337 GO:0050321 tau-protein kinase activity 2/844 22/18639 0.0909090909090909 2.00764756570444 0.262729911892149 0.647351345407337 GO:0070034 telomerase RNA binding 2/844 22/18639 0.0909090909090909 2.00764756570444 0.262729911892149 0.647351345407337 GO:0140517 protein-RNA adaptor activity 2/844 22/18639 0.0909090909090909 2.00764756570444 0.262729911892149 0.647351345407337 GO:0140784 metal ion sensor activity 2/844 22/18639 0.0909090909090909 2.00764756570444 0.262729911892149 0.647351345407337 GO:0019887 protein kinase regulator activity 14/844 255/18639 0.0549019607843137 1.21246166713131 0.267148626667549 0.656287839933405 GO:0004896 cytokine receptor activity 6/844 96/18639 0.0625 1.3802577014218 0.268277663348387 0.656287839933405 GO:0016407 acetyltransferase activity 6/844 96/18639 0.0625 1.3802577014218 0.268277663348387 0.656287839933405 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 3/844 40/18639 0.075 1.65630924170616 0.271086575331477 0.660008882932931 GO:0050997 quaternary ammonium group binding 3/844 40/18639 0.075 1.65630924170616 0.271086575331477 0.660008882932931 GO:0001786 phosphatidylserine binding 4/844 59/18639 0.0677966101694915 1.49722869306772 0.277788635028415 0.670050256969044 GO:0004879 nuclear receptor activity 4/844 59/18639 0.0677966101694915 1.49722869306772 0.277788635028415 0.670050256969044 GO:0015459 potassium channel regulator activity 4/844 59/18639 0.0677966101694915 1.49722869306772 0.277788635028415 0.670050256969044 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 2/844 23/18639 0.0869565217391304 1.92035854110859 0.279786839007562 0.670050256969044 GO:0004602 glutathione peroxidase activity 2/844 23/18639 0.0869565217391304 1.92035854110859 0.279786839007562 0.670050256969044 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 2/844 23/18639 0.0869565217391304 1.92035854110859 0.279786839007562 0.670050256969044 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/844 23/18639 0.0869565217391304 1.92035854110859 0.279786839007562 0.670050256969044 GO:0016922 nuclear receptor binding 8/844 137/18639 0.0583941605839416 1.28958383782475 0.281362448590305 0.672252936608537 GO:0016877 ligase activity, forming carbon-sulfur bonds 3/844 41/18639 0.0731707317073171 1.61591145532308 0.283546761019052 0.673601530961244 GO:0042169 SH2 domain binding 3/844 41/18639 0.0731707317073171 1.61591145532308 0.283546761019052 0.673601530961244 GO:0004725 protein tyrosine phosphatase activity 6/844 98/18639 0.0612244897959184 1.35208917690299 0.283898401341714 0.673601530961244 GO:0098531 ligand-modulated transcription factor activity 4/844 60/18639 0.0666666666666667 1.47227488151659 0.288004492131037 0.68176583010234 GO:0016859 cis-trans isomerase activity 3/844 42/18639 0.0714285714285714 1.57743737305349 0.296053587238889 0.694595533227359 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 2/844 24/18639 0.0833333333333333 1.84034360189573 0.296812530296179 0.694595533227359 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 2/844 24/18639 0.0833333333333333 1.84034360189573 0.296812530296179 0.694595533227359 GO:0015295 solute:proton symporter activity 2/844 24/18639 0.0833333333333333 1.84034360189573 0.296812530296179 0.694595533227359 GO:0050699 WW domain binding 2/844 24/18639 0.0833333333333333 1.84034360189573 0.296812530296179 0.694595533227359 GO:0016836 hydro-lyase activity 4/844 61/18639 0.0655737704918033 1.44813922772123 0.298271833534796 0.696420568048214 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 13/844 243/18639 0.0534979423868313 1.1814551518343 0.308330114856906 0.709815146801822 GO:0003707 nuclear steroid receptor activity 2/844 25/18639 0.08 1.76672985781991 0.313774874059488 0.709815146801822 GO:0008139 nuclear localization sequence binding 2/844 25/18639 0.08 1.76672985781991 0.313774874059488 0.709815146801822 GO:0019211 phosphatase activator activity 2/844 25/18639 0.08 1.76672985781991 0.313774874059488 0.709815146801822 GO:0004676 3-phosphoinositide-dependent protein kinase activity 13/844 245/18639 0.0530612244897959 1.17181061998259 0.318551187833013 0.709815146801822 GO:0004711 ribosomal protein S6 kinase activity 13/844 245/18639 0.0530612244897959 1.17181061998259 0.318551187833013 0.709815146801822 GO:0035175 histone H3S10 kinase activity 13/844 245/18639 0.0530612244897959 1.17181061998259 0.318551187833013 0.709815146801822 GO:0035979 histone H2AXS139 kinase activity 13/844 245/18639 0.0530612244897959 1.17181061998259 0.318551187833013 0.709815146801822 GO:0044022 histone H3S28 kinase activity 13/844 245/18639 0.0530612244897959 1.17181061998259 0.318551187833013 0.709815146801822 GO:0044023 histone H4S1 kinase activity 13/844 245/18639 0.0530612244897959 1.17181061998259 0.318551187833013 0.709815146801822 GO:0044024 histone H2AS1 kinase activity 13/844 245/18639 0.0530612244897959 1.17181061998259 0.318551187833013 0.709815146801822 GO:0044025 histone H2BS14 kinase activity 13/844 245/18639 0.0530612244897959 1.17181061998259 0.318551187833013 0.709815146801822 GO:0072354 histone H3T3 kinase activity 13/844 245/18639 0.0530612244897959 1.17181061998259 0.318551187833013 0.709815146801822 GO:0072371 histone H2AS121 kinase activity 13/844 245/18639 0.0530612244897959 1.17181061998259 0.318551187833013 0.709815146801822 GO:0072518 Rho-dependent protein serine/threonine kinase activity 13/844 245/18639 0.0530612244897959 1.17181061998259 0.318551187833013 0.709815146801822 GO:0140823 histone H2BS36 kinase activity 13/844 245/18639 0.0530612244897959 1.17181061998259 0.318551187833013 0.709815146801822 GO:0140855 histone H3S57 kinase activity 13/844 245/18639 0.0530612244897959 1.17181061998259 0.318551187833013 0.709815146801822 GO:0140995 histone H2A kinase activity 13/844 245/18639 0.0530612244897959 1.17181061998259 0.318551187833013 0.709815146801822 GO:0140997 histone H4 kinase activity 13/844 245/18639 0.0530612244897959 1.17181061998259 0.318551187833013 0.709815146801822 GO:0140998 histone H2B kinase activity 13/844 245/18639 0.0530612244897959 1.17181061998259 0.318551187833013 0.709815146801822 GO:1990244 histone H2AT120 kinase activity 13/844 245/18639 0.0530612244897959 1.17181061998259 0.318551187833013 0.709815146801822 GO:0003714 transcription corepressor activity 11/844 204/18639 0.053921568627451 1.19081056593253 0.31976074237563 0.710964774262519 GO:0005254 chloride channel activity 5/844 83/18639 0.0602409638554217 1.33036886884029 0.32280956584768 0.713579793523691 GO:0004677 DNA-dependent protein kinase activity 13/844 246/18639 0.0528455284552846 1.16704716217778 0.323692937820026 0.713579793523691 GO:0140857 histone H3T45 kinase activity 13/844 246/18639 0.0528455284552846 1.16704716217778 0.323692937820026 0.713579793523691 GO:0005253 monoatomic anion channel activity 6/844 103/18639 0.058252427184466 1.28645377996595 0.323721564866845 0.713579793523691 GO:0035402 histone H3T11 kinase activity 13/844 247/18639 0.0526315789473684 1.16232227488152 0.328854148737988 0.721086898334142 GO:0035403 histone H3T6 kinase activity 13/844 247/18639 0.0526315789473684 1.16232227488152 0.328854148737988 0.721086898334142 GO:0004112 cyclic-nucleotide phosphodiesterase activity 2/844 26/18639 0.0769230769230769 1.69877870944222 0.330644724114192 0.721086898334142 GO:0005160 transforming growth factor beta receptor binding 2/844 26/18639 0.0769230769230769 1.69877870944222 0.330644724114192 0.721086898334142 GO:0034237 protein kinase A regulatory subunit binding 2/844 26/18639 0.0769230769230769 1.69877870944222 0.330644724114192 0.721086898334142 GO:0004679 AMP-activated protein kinase activity 13/844 248/18639 0.0524193548387097 1.15763549151506 0.33403380551702 0.726931317738739 GO:0015399 primary active transmembrane transporter activity 9/844 166/18639 0.0542168674698795 1.19733198195626 0.338412272773521 0.734552250520916 GO:0019843 rRNA binding 4/844 65/18639 0.0615384615384615 1.35902296755377 0.33968562609455 0.734552250520916 GO:0120013 lipid transfer activity 4/844 65/18639 0.0615384615384615 1.35902296755377 0.33968562609455 0.734552250520916 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 3/844 46/18639 0.0652173913043478 1.44026890583144 0.346253214400574 0.746500188768146 GO:0004683 calcium/calmodulin-dependent protein kinase activity 2/844 27/18639 0.0740740740740741 1.63586097946288 0.347395697602347 0.746500188768146 GO:0008320 protein transmembrane transporter activity 2/844 27/18639 0.0740740740740741 1.63586097946288 0.347395697602347 0.746500188768146 GO:0016209 antioxidant activity 5/844 86/18639 0.0581395348837209 1.2839606524854 0.349913255357971 0.750337001552134 GO:0019888 protein phosphatase regulator activity 6/844 107/18639 0.0560747663551402 1.23836204987377 0.356111594308382 0.756559857001454 GO:0004843 cysteine-type deubiquitinase activity 6/844 108/18639 0.0555555555555556 1.22689573459716 0.364250722193947 0.756559857001454 GO:0030145 manganese ion binding 4/844 68/18639 0.0588235294117647 1.2990660719264 0.370881675410509 0.756559857001454 GO:0003796 lysozyme activity 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.756559857001454 GO:0004382 GDP phosphatase activity 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.756559857001454 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.756559857001454 GO:0004935 adrenergic receptor activity 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.756559857001454 GO:0005131 growth hormone receptor binding 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.756559857001454 GO:0005522 profilin binding 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.756559857001454 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.756559857001454 GO:0015203 polyamine transmembrane transporter activity 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.756559857001454 GO:0016303 1-phosphatidylinositol-3-kinase activity 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.756559857001454 GO:0019531 oxalate transmembrane transporter activity 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.756559857001454 GO:0019911 structural constituent of myelin sheath 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.756559857001454 GO:0043121 neurotrophin binding 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.756559857001454 GO:0043208 glycosphingolipid binding 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.756559857001454 GO:0043295 glutathione binding 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.756559857001454 GO:0045322 unmethylated CpG binding 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.756559857001454 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.756559857001454 GO:0051378 serotonin binding 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.756559857001454 GO:0051880 G-quadruplex DNA binding 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.756559857001454 GO:0140135 mechanosensitive monoatomic cation channel activity 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.756559857001454 GO:0140999 histone H3K4 trimethyltransferase activity 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.756559857001454 GO:1905394 retromer complex binding 1/844 10/18639 0.1 2.20841232227488 0.370922586126663 0.756559857001454 GO:0140693 molecular condensate scaffold activity 3/844 48/18639 0.0625 1.3802577014218 0.371267910313884 0.756559857001454 GO:0004620 phospholipase activity 6/844 109/18639 0.055045871559633 1.21563981042654 0.37239902246296 0.757359123064552 GO:0005261 monoatomic cation channel activity 17/844 341/18639 0.0498533724340176 1.10096801990243 0.376883297681746 0.759571367633391 GO:0005216 monoatomic ion channel activity 22/844 448/18639 0.0491071428571429 1.08448819397427 0.378395569978233 0.759571367633391 GO:0004181 metallocarboxypeptidase activity 2/844 29/18639 0.0689655172413793 1.52304298087923 0.380448171617752 0.759571367633391 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 2/844 29/18639 0.0689655172413793 1.52304298087923 0.380448171617752 0.759571367633391 GO:0016417 S-acyltransferase activity 2/844 29/18639 0.0689655172413793 1.52304298087923 0.380448171617752 0.759571367633391 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 2/844 29/18639 0.0689655172413793 1.52304298087923 0.380448171617752 0.759571367633391 GO:0097472 cyclin-dependent protein kinase activity 2/844 29/18639 0.0689655172413793 1.52304298087923 0.380448171617752 0.759571367633391 GO:0106222 lncRNA binding 2/844 29/18639 0.0689655172413793 1.52304298087923 0.380448171617752 0.759571367633391 GO:0001222 transcription corepressor binding 3/844 49/18639 0.0612244897959184 1.35208917690299 0.383711189522433 0.759571367633391 GO:0060590 ATPase regulator activity 3/844 49/18639 0.0612244897959184 1.35208917690299 0.383711189522433 0.759571367633391 GO:0016782 transferase activity, transferring sulphur-containing groups 4/844 70/18639 0.0571428571428571 1.26194989844279 0.391630815446132 0.759571367633391 GO:0004721 phosphoprotein phosphatase activity 9/844 175/18639 0.0514285714285714 1.13575490859851 0.39652387063121 0.759571367633391 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 2/844 30/18639 0.0666666666666667 1.47227488151659 0.396709069998572 0.759571367633391 GO:0015215 nucleotide transmembrane transporter activity 2/844 30/18639 0.0666666666666667 1.47227488151659 0.396709069998572 0.759571367633391 GO:0000099 sulfur amino acid transmembrane transporter activity 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.759571367633391 GO:0004016 adenylate cyclase activity 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.759571367633391 GO:0005114 type II transforming growth factor beta receptor binding 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.759571367633391 GO:0005536 D-glucose binding 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.759571367633391 GO:0008432 JUN kinase binding 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.759571367633391 GO:0008503 benzodiazepine receptor activity 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.759571367633391 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.759571367633391 GO:0016594 glycine binding 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.759571367633391 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.759571367633391 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.759571367633391 GO:0034056 estrogen response element binding 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.759571367633391 GO:0034511 U3 snoRNA binding 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.759571367633391 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.759571367633391 GO:0034713 type I transforming growth factor beta receptor binding 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.759571367633391 GO:0045294 alpha-catenin binding 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.759571367633391 GO:0048407 platelet-derived growth factor binding 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.759571367633391 GO:0050786 RAGE receptor binding 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.759571367633391 GO:0070990 snRNP binding 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.759571367633391 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.759571367633391 GO:0180030 inositol phosphate kinase activity 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.759571367633391 GO:1900750 oligopeptide binding 1/844 11/18639 0.0909090909090909 2.00764756570444 0.399423382589656 0.759571367633391 GO:0140299 molecular sensor activity 4/844 71/18639 0.0563380281690141 1.2441759562112 0.40197008546445 0.762998773335299 GO:0052689 carboxylic ester hydrolase activity 5/844 92/18639 0.0543478260869565 1.20022408819287 0.404318594511744 0.765849826267014 GO:0016830 carbon-carbon lyase activity 3/844 51/18639 0.0588235294117647 1.2990660719264 0.408415359720959 0.765849826267014 GO:0030544 Hsp70 protein binding 3/844 51/18639 0.0588235294117647 1.2990660719264 0.408415359720959 0.765849826267014 GO:0005310 dicarboxylic acid transmembrane transporter activity 2/844 31/18639 0.0645161290322581 1.42478214340315 0.41276956250398 0.765849826267014 GO:0016411 acylglycerol O-acyltransferase activity 2/844 31/18639 0.0645161290322581 1.42478214340315 0.41276956250398 0.765849826267014 GO:0099094 ligand-gated monoatomic cation channel activity 7/844 136/18639 0.0514705882352941 1.1366828129356 0.419735663573414 0.765849826267014 GO:0140789 histone phosphatase activity 7/844 136/18639 0.0514705882352941 1.1366828129356 0.419735663573414 0.765849826267014 GO:0016829 lyase activity 10/844 200/18639 0.05 1.10420616113744 0.420163699923701 0.765849826267014 GO:0101005 deubiquitinase activity 6/844 115/18639 0.0521739130434783 1.15221512466516 0.421281872240877 0.765849826267014 GO:0000995 RNA polymerase III general transcription initiation factor activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.765849826267014 GO:0005436 sodium:phosphate symporter activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.765849826267014 GO:0015132 prostaglandin transmembrane transporter activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.765849826267014 GO:0015166 polyol transmembrane transporter activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.765849826267014 GO:0015269 calcium-activated potassium channel activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.765849826267014 GO:0016208 AMP binding 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.765849826267014 GO:0016801 hydrolase activity, acting on ether bonds 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.765849826267014 GO:0016803 ether hydrolase activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.765849826267014 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.765849826267014 GO:0035197 siRNA binding 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.765849826267014 GO:0035497 cAMP response element binding 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.765849826267014 GO:0042301 phosphate ion binding 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.765849826267014 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.765849826267014 GO:0070008 serine-type exopeptidase activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.765849826267014 GO:0070410 co-SMAD binding 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.765849826267014 GO:0070679 inositol 1,4,5 trisphosphate binding 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.765849826267014 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.765849826267014 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.765849826267014 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.765849826267014 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.765849826267014 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.765849826267014 GO:0140900 chloride:bicarbonate antiporter activity 1/844 12/18639 0.0833333333333333 1.84034360189573 0.426634391022893 0.765849826267014 GO:0016887 ATP hydrolysis activity 20/844 417/18639 0.0479616306954436 1.05919056224215 0.428228636311136 0.767367748634465 GO:0005544 calcium-dependent phospholipid binding 3/844 53/18639 0.0566037735849057 1.25004471072163 0.432810936239851 0.774225496764131 GO:0019208 phosphatase regulator activity 6/844 117/18639 0.0512820512820513 1.13251913962814 0.437491947335167 0.780485482493753 GO:0099106 ion channel regulator activity 8/844 160/18639 0.05 1.10420616113744 0.438700813527982 0.780485482493753 GO:0042393 histone binding 12/844 247/18639 0.048582995951417 1.0729128691214 0.443354446189866 0.780485482493753 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 2/844 33/18639 0.0606060606060606 1.33843171046963 0.444230331235618 0.780485482493753 GO:0003925 G protein activity 3/844 54/18639 0.0555555555555556 1.22689573459716 0.444870633091544 0.780485482493753 GO:0140463 chromatin-protein adaptor activity 3/844 54/18639 0.0555555555555556 1.22689573459716 0.444870633091544 0.780485482493753 GO:0022853 active monoatomic ion transmembrane transporter activity 6/844 118/18639 0.0508474576271186 1.12292151980079 0.44556670688828 0.780485482493753 GO:0002161 aminoacyl-tRNA editing activity 1/844 13/18639 0.0769230769230769 1.69877870944222 0.452613913972197 0.780485482493753 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 1/844 13/18639 0.0769230769230769 1.69877870944222 0.452613913972197 0.780485482493753 GO:0008035 high-density lipoprotein particle binding 1/844 13/18639 0.0769230769230769 1.69877870944222 0.452613913972197 0.780485482493753 GO:0008417 fucosyltransferase activity 1/844 13/18639 0.0769230769230769 1.69877870944222 0.452613913972197 0.780485482493753 GO:0009982 pseudouridine synthase activity 1/844 13/18639 0.0769230769230769 1.69877870944222 0.452613913972197 0.780485482493753 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/844 13/18639 0.0769230769230769 1.69877870944222 0.452613913972197 0.780485482493753 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/844 13/18639 0.0769230769230769 1.69877870944222 0.452613913972197 0.780485482493753 GO:0046974 histone H3K9 methyltransferase activity 1/844 13/18639 0.0769230769230769 1.69877870944222 0.452613913972197 0.780485482493753 GO:0046975 histone H3K36 methyltransferase activity 1/844 13/18639 0.0769230769230769 1.69877870944222 0.452613913972197 0.780485482493753 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 1/844 13/18639 0.0769230769230769 1.69877870944222 0.452613913972197 0.780485482493753 GO:0070700 BMP receptor binding 1/844 13/18639 0.0769230769230769 1.69877870944222 0.452613913972197 0.780485482493753 GO:0071714 icosanoid transmembrane transporter activity 1/844 13/18639 0.0769230769230769 1.69877870944222 0.452613913972197 0.780485482493753 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/844 13/18639 0.0769230769230769 1.69877870944222 0.452613913972197 0.780485482493753 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 1/844 13/18639 0.0769230769230769 1.69877870944222 0.452613913972197 0.780485482493753 GO:0017022 myosin binding 4/844 76/18639 0.0526315789473684 1.16232227488152 0.453062304471983 0.780485482493753 GO:0140313 molecular sequestering activity 3/844 55/18639 0.0545454545454545 1.20458853942266 0.456827455270894 0.785651244383668 GO:0052866 phosphatidylinositol phosphate phosphatase activity 2/844 34/18639 0.0588235294117647 1.2990660719264 0.459605436814115 0.789104811950533 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 11/844 229/18639 0.0480349344978166 1.06080941244645 0.464386716670131 0.793116794243451 GO:0022836 gated channel activity 15/844 318/18639 0.0471698113207547 1.04170392560136 0.473121447944138 0.793116794243451 GO:0010485 histone H4 acetyltransferase activity 2/844 35/18639 0.0571428571428571 1.26194989844279 0.474729543258764 0.793116794243451 GO:0061631 ubiquitin conjugating enzyme activity 2/844 35/18639 0.0571428571428571 1.26194989844279 0.474729543258764 0.793116794243451 GO:0043130 ubiquitin binding 5/844 100/18639 0.05 1.10420616113744 0.475790485409009 0.793116794243451 GO:0005161 platelet-derived growth factor receptor binding 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.793116794243451 GO:0005313 L-glutamate transmembrane transporter activity 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.793116794243451 GO:0008174 mRNA methyltransferase activity 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.793116794243451 GO:0008191 metalloendopeptidase inhibitor activity 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.793116794243451 GO:0008559 ABC-type xenobiotic transporter activity 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.793116794243451 GO:0015386 potassium:proton antiporter activity 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.793116794243451 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.793116794243451 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.793116794243451 GO:0042043 neurexin family protein binding 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.793116794243451 GO:0043176 amine binding 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.793116794243451 GO:0046030 inositol trisphosphate phosphatase activity 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.793116794243451 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.793116794243451 GO:0061665 SUMO ligase activity 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.793116794243451 GO:0061783 peptidoglycan muralytic activity 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.793116794243451 GO:0071933 Arp2/3 complex binding 1/844 14/18639 0.0714285714285714 1.57743737305349 0.477417621510448 0.793116794243451 GO:0004601 peroxidase activity 3/844 57/18639 0.0526315789473684 1.16232227488152 0.480403248741816 0.796785323560455 GO:0016835 carbon-oxygen lyase activity 4/844 79/18639 0.0506329113924051 1.1181834543164 0.483032588915174 0.799852025263414 GO:0055106 ubiquitin-protein transferase regulator activity 2/844 36/18639 0.0555555555555556 1.22689573459716 0.489593840711313 0.805511535680731 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 2/844 36/18639 0.0555555555555556 1.22689573459716 0.489593840711313 0.805511535680731 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 2/844 36/18639 0.0555555555555556 1.22689573459716 0.489593840711313 0.805511535680731 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 2/844 36/18639 0.0555555555555556 1.22689573459716 0.489593840711313 0.805511535680731 GO:0016247 channel regulator activity 8/844 168/18639 0.0476190476190476 1.05162491536899 0.493437509098227 0.810534369912954 GO:0005523 tropomyosin binding 1/844 15/18639 0.0666666666666667 1.47227488151659 0.50109866996388 0.811296075599307 GO:0017081 chloride channel regulator activity 1/844 15/18639 0.0666666666666667 1.47227488151659 0.50109866996388 0.811296075599307 GO:0030553 cGMP binding 1/844 15/18639 0.0666666666666667 1.47227488151659 0.50109866996388 0.811296075599307 GO:0033130 acetylcholine receptor binding 1/844 15/18639 0.0666666666666667 1.47227488151659 0.50109866996388 0.811296075599307 GO:0034483 heparan sulfate sulfotransferase activity 1/844 15/18639 0.0666666666666667 1.47227488151659 0.50109866996388 0.811296075599307 GO:0050700 CARD domain binding 1/844 15/18639 0.0666666666666667 1.47227488151659 0.50109866996388 0.811296075599307 GO:0050780 dopamine receptor binding 1/844 15/18639 0.0666666666666667 1.47227488151659 0.50109866996388 0.811296075599307 GO:0120283 protein serine/threonine kinase binding 1/844 15/18639 0.0666666666666667 1.47227488151659 0.50109866996388 0.811296075599307 GO:0140161 monocarboxylate:sodium symporter activity 1/844 15/18639 0.0666666666666667 1.47227488151659 0.50109866996388 0.811296075599307 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 3/844 59/18639 0.0508474576271186 1.12292151980079 0.503484978627368 0.811296075599307 GO:0022829 wide pore channel activity 2/844 37/18639 0.0540540540540541 1.19373639041885 0.504190829421228 0.811296075599307 GO:0023023 MHC protein complex binding 2/844 37/18639 0.0540540540540541 1.19373639041885 0.504190829421228 0.811296075599307 GO:0030551 cyclic nucleotide binding 2/844 37/18639 0.0540540540540541 1.19373639041885 0.504190829421228 0.811296075599307 GO:0141108 transporter regulator activity 8/844 170/18639 0.0470588235294118 1.03925285754112 0.506902885427642 0.814381594926854 GO:0019783 ubiquitin-like protein peptidase activity 6/844 127/18639 0.047244094488189 1.04334440422435 0.516814832507147 0.824578357407182 GO:0008236 serine-type peptidase activity 9/844 194/18639 0.0463917525773196 1.0245211804368 0.518630635665057 0.824578357407182 GO:0000062 fatty-acyl-CoA binding 1/844 16/18639 0.0625 1.3802577014218 0.52370781528983 0.824578357407182 GO:0005149 interleukin-1 receptor binding 1/844 16/18639 0.0625 1.3802577014218 0.52370781528983 0.824578357407182 GO:0005521 lamin binding 1/844 16/18639 0.0625 1.3802577014218 0.52370781528983 0.824578357407182 GO:0015385 sodium:proton antiporter activity 1/844 16/18639 0.0625 1.3802577014218 0.52370781528983 0.824578357407182 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/844 16/18639 0.0625 1.3802577014218 0.52370781528983 0.824578357407182 GO:0022841 potassium ion leak channel activity 1/844 16/18639 0.0625 1.3802577014218 0.52370781528983 0.824578357407182 GO:0030275 LRR domain binding 1/844 16/18639 0.0625 1.3802577014218 0.52370781528983 0.824578357407182 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/844 16/18639 0.0625 1.3802577014218 0.52370781528983 0.824578357407182 GO:0034450 ubiquitin-ubiquitin ligase activity 1/844 16/18639 0.0625 1.3802577014218 0.52370781528983 0.824578357407182 GO:0055102 lipase inhibitor activity 1/844 16/18639 0.0625 1.3802577014218 0.52370781528983 0.824578357407182 GO:0070411 I-SMAD binding 1/844 16/18639 0.0625 1.3802577014218 0.52370781528983 0.824578357407182 GO:0000149 SNARE binding 5/844 106/18639 0.0471698113207547 1.04170392560136 0.527489407609476 0.828370632902625 GO:0035591 signaling adaptor activity 6/844 129/18639 0.0465116279069767 1.02716852198832 0.53218595984978 0.828370632902625 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 2/844 39/18639 0.0512820512820513 1.13251913962814 0.532558836522737 0.828370632902625 GO:0016776 phosphotransferase activity, phosphate group as acceptor 2/844 39/18639 0.0512820512820513 1.13251913962814 0.532558836522737 0.828370632902625 GO:0016298 lipase activity 6/844 130/18639 0.0461538461538462 1.01926722566533 0.539794711013039 0.828370632902625 GO:0017171 serine hydrolase activity 9/844 198/18639 0.0454545454545455 1.00382378285222 0.543455368915455 0.828370632902625 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.828370632902625 GO:0005092 GDP-dissociation inhibitor activity 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.828370632902625 GO:0008429 phosphatidylethanolamine binding 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.828370632902625 GO:0008569 minus-end-directed microtubule motor activity 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.828370632902625 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.828370632902625 GO:0016018 cyclosporin A binding 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.828370632902625 GO:0017110 nucleoside diphosphate phosphatase activity 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.828370632902625 GO:0030169 low-density lipoprotein particle binding 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.828370632902625 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.828370632902625 GO:0030548 acetylcholine receptor regulator activity 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.828370632902625 GO:0032183 SUMO binding 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.828370632902625 GO:0048038 quinone binding 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.828370632902625 GO:0051787 misfolded protein binding 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.828370632902625 GO:0070402 NADPH binding 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.828370632902625 GO:1901567 fatty acid derivative binding 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.828370632902625 GO:1990226 histone methyltransferase binding 1/844 17/18639 0.0588235294117647 1.2990660719264 0.545293521346608 0.828370632902625 GO:0030331 nuclear estrogen receptor binding 2/844 40/18639 0.05 1.10420616113744 0.54632053448017 0.828370632902625 GO:0071855 neuropeptide receptor binding 2/844 40/18639 0.05 1.10420616113744 0.54632053448017 0.828370632902625 GO:0071949 FAD binding 2/844 40/18639 0.05 1.10420616113744 0.54632053448017 0.828370632902625 GO:0031072 heat shock protein binding 6/844 131/18639 0.0458015267175573 1.01148655982056 0.547349544417229 0.828704997086646 GO:0043021 ribonucleoprotein complex binding 8/844 177/18639 0.0451977401129944 0.998152462045144 0.553049993067696 0.834603762399274 GO:0005179 hormone activity 6/844 132/18639 0.0454545454545455 1.00382378285222 0.55484853315098 0.834603762399274 GO:0004386 helicase activity 7/844 155/18639 0.0451612903225806 0.997347500382205 0.557194876574099 0.834603762399274 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 12/844 268/18639 0.0447761194029851 0.988841338332036 0.55769747365334 0.834603762399274 GO:0004536 DNA nuclease activity 3/844 64/18639 0.046875 1.03519327606635 0.558746993312308 0.834603762399274 GO:0061650 ubiquitin-like protein conjugating enzyme activity 2/844 41/18639 0.0487804878048781 1.07727430354872 0.559796112606382 0.834603762399274 GO:0000900 mRNA regulatory element binding translation repressor activity 1/844 18/18639 0.0555555555555556 1.22689573459716 0.565902063285361 0.834603762399274 GO:0003746 translation elongation factor activity 1/844 18/18639 0.0555555555555556 1.22689573459716 0.565902063285361 0.834603762399274 GO:0015280 ligand-gated sodium channel activity 1/844 18/18639 0.0555555555555556 1.22689573459716 0.565902063285361 0.834603762399274 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/844 18/18639 0.0555555555555556 1.22689573459716 0.565902063285361 0.834603762399274 GO:0022851 GABA-gated chloride ion channel activity 1/844 18/18639 0.0555555555555556 1.22689573459716 0.565902063285361 0.834603762399274 GO:0031690 adrenergic receptor binding 1/844 18/18639 0.0555555555555556 1.22689573459716 0.565902063285361 0.834603762399274 GO:0050811 GABA receptor binding 1/844 18/18639 0.0555555555555556 1.22689573459716 0.565902063285361 0.834603762399274 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/844 18/18639 0.0555555555555556 1.22689573459716 0.565902063285361 0.834603762399274 GO:0070628 proteasome binding 1/844 18/18639 0.0555555555555556 1.22689573459716 0.565902063285361 0.834603762399274 GO:0098641 cadherin binding involved in cell-cell adhesion 1/844 18/18639 0.0555555555555556 1.22689573459716 0.565902063285361 0.834603762399274 GO:0099602 neurotransmitter receptor regulator activity 1/844 18/18639 0.0555555555555556 1.22689573459716 0.565902063285361 0.834603762399274 GO:1990381 ubiquitin-specific protease binding 1/844 18/18639 0.0555555555555556 1.22689573459716 0.565902063285361 0.834603762399274 GO:0004402 histone acetyltransferase activity 2/844 42/18639 0.0476190476190476 1.05162491536899 0.572983238874757 0.84141521467998 GO:0004520 DNA endonuclease activity 2/844 42/18639 0.0476190476190476 1.05162491536899 0.572983238874757 0.84141521467998 GO:0019894 kinesin binding 2/844 42/18639 0.0476190476190476 1.05162491536899 0.572983238874757 0.84141521467998 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 8/844 181/18639 0.0441988950276243 0.976093844099395 0.57859891732296 0.843437341887891 GO:0004890 GABA-A receptor activity 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.843437341887891 GO:0005229 intracellularly calcium-gated chloride channel activity 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.843437341887891 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.843437341887891 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.843437341887891 GO:0022821 solute:potassium antiporter activity 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.843437341887891 GO:0022840 leak channel activity 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.843437341887891 GO:0022842 narrow pore channel activity 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.843437341887891 GO:0031420 alkali metal ion binding 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.843437341887891 GO:0050145 nucleoside monophosphate kinase activity 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.843437341887891 GO:0097001 ceramide binding 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.843437341887891 GO:0120227 acyl-CoA binding 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.843437341887891 GO:0141147 intracellularly calcium-gated channel activity 1/844 19/18639 0.0526315789473684 1.16232227488152 0.585577626283437 0.843437341887891 GO:0008200 ion channel inhibitor activity 2/844 43/18639 0.0465116279069767 1.02716852198832 0.585880377974808 0.843437341887891 GO:0016248 channel inhibitor activity 2/844 44/18639 0.0454545454545455 1.00382378285222 0.59848672409896 0.853266473587654 GO:0016790 thiolester hydrolase activity 2/844 44/18639 0.0454545454545455 1.00382378285222 0.59848672409896 0.853266473587654 GO:0019205 nucleobase-containing compound kinase activity 2/844 44/18639 0.0454545454545455 1.00382378285222 0.59848672409896 0.853266473587654 GO:1990841 promoter-specific chromatin binding 3/844 68/18639 0.0441176470588235 0.974299553944801 0.600183876438361 0.853266473587654 GO:0017124 SH3 domain binding 5/844 115/18639 0.0434782608695652 0.960179270554296 0.600430380879598 0.853266473587654 GO:0008083 growth factor activity 7/844 162/18639 0.0432098765432099 0.95425223802001 0.604197501116901 0.853266473587654 GO:0001972 retinoic acid binding 1/844 20/18639 0.05 1.10420616113744 0.604362399828914 0.853266473587654 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/844 20/18639 0.05 1.10420616113744 0.604362399828914 0.853266473587654 GO:0016004 phospholipase activator activity 1/844 20/18639 0.05 1.10420616113744 0.604362399828914 0.853266473587654 GO:0016408 C-acyltransferase activity 1/844 20/18639 0.05 1.10420616113744 0.604362399828914 0.853266473587654 GO:0016505 peptidase activator activity involved in apoptotic process 1/844 20/18639 0.05 1.10420616113744 0.604362399828914 0.853266473587654 GO:0030742 GTP-dependent protein binding 1/844 20/18639 0.05 1.10420616113744 0.604362399828914 0.853266473587654 GO:0052745 inositol phosphate phosphatase activity 1/844 20/18639 0.05 1.10420616113744 0.604362399828914 0.853266473587654 GO:0061608 nuclear import signal receptor activity 1/844 20/18639 0.05 1.10420616113744 0.604362399828914 0.853266473587654 GO:0070851 growth factor receptor binding 6/844 139/18639 0.0431654676258993 0.953271506017935 0.605633336527855 0.853884690427856 GO:0009055 electron transfer activity 5/844 116/18639 0.0431034482758621 0.951901863049518 0.608134633495818 0.854123044508998 GO:0001217 DNA-binding transcription repressor activity 12/844 278/18639 0.0431654676258993 0.953271506017935 0.609026757517617 0.854123044508998 GO:0015276 ligand-gated monoatomic ion channel activity 8/844 186/18639 0.043010752688172 0.949854762268766 0.609548629717128 0.854123044508998 GO:0008080 N-acetyltransferase activity 3/844 69/18639 0.0434782608695652 0.960179270554296 0.610134699139013 0.854123044508998 GO:0042605 peptide antigen binding 2/844 45/18639 0.0444444444444444 0.981516587677725 0.610802138170825 0.854123044508998 GO:0141110 transporter inhibitor activity 2/844 45/18639 0.0444444444444444 0.981516587677725 0.610802138170825 0.854123044508998 GO:0051219 phosphoprotein binding 4/844 93/18639 0.043010752688172 0.949854762268766 0.612401173037079 0.855192373791562 GO:0022834 ligand-gated channel activity 8/844 188/18639 0.0425531914893617 0.93974992437229 0.621595161177416 0.85673773409402 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/844 21/18639 0.0476190476190476 1.05162491536899 0.622296667756536 0.85673773409402 GO:0009975 cyclase activity 1/844 21/18639 0.0476190476190476 1.05162491536899 0.622296667756536 0.85673773409402 GO:0010314 phosphatidylinositol-5-phosphate binding 1/844 21/18639 0.0476190476190476 1.05162491536899 0.622296667756536 0.85673773409402 GO:0035613 RNA stem-loop binding 1/844 21/18639 0.0476190476190476 1.05162491536899 0.622296667756536 0.85673773409402 GO:0140312 cargo adaptor activity 1/844 21/18639 0.0476190476190476 1.05162491536899 0.622296667756536 0.85673773409402 GO:0004180 carboxypeptidase activity 2/844 46/18639 0.0434782608695652 0.960179270554296 0.622827089251291 0.85673773409402 GO:0030291 protein serine/threonine kinase inhibitor activity 2/844 46/18639 0.0434782608695652 0.960179270554296 0.622827089251291 0.85673773409402 GO:0001784 phosphotyrosine residue binding 2/844 47/18639 0.0425531914893617 0.93974992437229 0.634562599873509 0.85673773409402 GO:0061733 protein-lysine-acetyltransferase activity 2/844 47/18639 0.0425531914893617 0.93974992437229 0.634562599873509 0.85673773409402 GO:0061749 forked DNA-dependent helicase activity 2/844 47/18639 0.0425531914893617 0.93974992437229 0.634562599873509 0.85673773409402 GO:0099095 ligand-gated monoatomic anion channel activity 2/844 47/18639 0.0425531914893617 0.93974992437229 0.634562599873509 0.85673773409402 GO:0140938 histone H3 methyltransferase activity 2/844 47/18639 0.0425531914893617 0.93974992437229 0.634562599873509 0.85673773409402 GO:1990518 single-stranded 3'-5' DNA helicase activity 2/844 47/18639 0.0425531914893617 0.93974992437229 0.634562599873509 0.85673773409402 GO:0032182 ubiquitin-like protein binding 5/844 120/18639 0.0416666666666667 0.920171800947867 0.6380759097119 0.85673773409402 GO:0008970 phospholipase A1 activity 1/844 22/18639 0.0454545454545455 1.00382378285222 0.639418894226268 0.85673773409402 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/844 22/18639 0.0454545454545455 1.00382378285222 0.639418894226268 0.85673773409402 GO:0032931 histone H3K56 acetyltransferase activity 1/844 22/18639 0.0454545454545455 1.00382378285222 0.639418894226268 0.85673773409402 GO:0043992 histone H3K9 acetyltransferase activity 1/844 22/18639 0.0454545454545455 1.00382378285222 0.639418894226268 0.85673773409402 GO:0043993 histone H3K18 acetyltransferase activity 1/844 22/18639 0.0454545454545455 1.00382378285222 0.639418894226268 0.85673773409402 GO:0043994 histone H3K23 acetyltransferase activity 1/844 22/18639 0.0454545454545455 1.00382378285222 0.639418894226268 0.85673773409402 GO:0043999 histone H2AK5 acetyltransferase activity 1/844 22/18639 0.0454545454545455 1.00382378285222 0.639418894226268 0.85673773409402 GO:0044012 histone H2AK9 acetyltransferase activity 1/844 22/18639 0.0454545454545455 1.00382378285222 0.639418894226268 0.85673773409402 GO:0044014 histone H2BK5 acetyltransferase activity 1/844 22/18639 0.0454545454545455 1.00382378285222 0.639418894226268 0.85673773409402 GO:0044015 histone H2BK12 acetyltransferase activity 1/844 22/18639 0.0454545454545455 1.00382378285222 0.639418894226268 0.85673773409402 GO:0044016 histone H3K4 acetyltransferase activity 1/844 22/18639 0.0454545454545455 1.00382378285222 0.639418894226268 0.85673773409402 GO:0044017 histone H3K27 acetyltransferase activity 1/844 22/18639 0.0454545454545455 1.00382378285222 0.639418894226268 0.85673773409402 GO:0044018 histone H3K36 acetyltransferase activity 1/844 22/18639 0.0454545454545455 1.00382378285222 0.639418894226268 0.85673773409402 GO:0046972 histone H4K16 acetyltransferase activity 1/844 22/18639 0.0454545454545455 1.00382378285222 0.639418894226268 0.85673773409402 GO:0061133 endopeptidase activator activity 1/844 22/18639 0.0454545454545455 1.00382378285222 0.639418894226268 0.85673773409402 GO:0140908 histone H3K122 acetyltransferase activity 1/844 22/18639 0.0454545454545455 1.00382378285222 0.639418894226268 0.85673773409402 GO:0009378 four-way junction helicase activity 2/844 48/18639 0.0416666666666667 0.920171800947867 0.646010195071753 0.858441827551464 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/844 48/18639 0.0416666666666667 0.920171800947867 0.646010195071753 0.858441827551464 GO:0032266 phosphatidylinositol-3-phosphate binding 2/844 48/18639 0.0416666666666667 0.920171800947867 0.646010195071753 0.858441827551464 GO:0036121 double-stranded DNA helicase activity 2/844 48/18639 0.0416666666666667 0.920171800947867 0.646010195071753 0.858441827551464 GO:0038187 pattern recognition receptor activity 2/844 48/18639 0.0416666666666667 0.920171800947867 0.646010195071753 0.858441827551464 GO:0043138 3'-5' DNA helicase activity 2/844 48/18639 0.0416666666666667 0.920171800947867 0.646010195071753 0.858441827551464 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 5/844 122/18639 0.040983606557377 0.905087017325771 0.652504788554994 0.858441827551464 GO:0000295 adenine nucleotide transmembrane transporter activity 1/844 23/18639 0.0434782608695652 0.960179270554296 0.655765805827119 0.858441827551464 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/844 23/18639 0.0434782608695652 0.960179270554296 0.655765805827119 0.858441827551464 GO:0005212 structural constituent of eye lens 1/844 23/18639 0.0434782608695652 0.960179270554296 0.655765805827119 0.858441827551464 GO:0016493 C-C chemokine receptor activity 1/844 23/18639 0.0434782608695652 0.960179270554296 0.655765805827119 0.858441827551464 GO:0016849 phosphorus-oxygen lyase activity 1/844 23/18639 0.0434782608695652 0.960179270554296 0.655765805827119 0.858441827551464 GO:0016917 GABA receptor activity 1/844 23/18639 0.0434782608695652 0.960179270554296 0.655765805827119 0.858441827551464 GO:0031681 G-protein beta-subunit binding 1/844 23/18639 0.0434782608695652 0.960179270554296 0.655765805827119 0.858441827551464 GO:0042171 lysophosphatidic acid acyltransferase activity 1/844 23/18639 0.0434782608695652 0.960179270554296 0.655765805827119 0.858441827551464 GO:0044013 histone H2B acetyltransferase activity 1/844 23/18639 0.0434782608695652 0.960179270554296 0.655765805827119 0.858441827551464 GO:0070577 lysine-acetylated histone binding 1/844 23/18639 0.0434782608695652 0.960179270554296 0.655765805827119 0.858441827551464 GO:0071617 lysophospholipid acyltransferase activity 1/844 23/18639 0.0434782608695652 0.960179270554296 0.655765805827119 0.858441827551464 GO:0035064 methylated histone binding 3/844 74/18639 0.0405405405405405 0.895302292814141 0.657360539464365 0.859431827743589 GO:0004622 lysophospholipase activity 1/844 24/18639 0.0416666666666667 0.920171800947867 0.671372469980638 0.863433854115626 GO:0005315 phosphate transmembrane transporter activity 1/844 24/18639 0.0416666666666667 0.920171800947867 0.671372469980638 0.863433854115626 GO:0005540 hyaluronic acid binding 1/844 24/18639 0.0416666666666667 0.920171800947867 0.671372469980638 0.863433854115626 GO:0019957 C-C chemokine binding 1/844 24/18639 0.0416666666666667 0.920171800947867 0.671372469980638 0.863433854115626 GO:0030552 cAMP binding 1/844 24/18639 0.0416666666666667 0.920171800947867 0.671372469980638 0.863433854115626 GO:0035035 histone acetyltransferase binding 1/844 24/18639 0.0416666666666667 0.920171800947867 0.671372469980638 0.863433854115626 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/844 24/18639 0.0416666666666667 0.920171800947867 0.671372469980638 0.863433854115626 GO:0043998 histone H2A acetyltransferase activity 1/844 24/18639 0.0416666666666667 0.920171800947867 0.671372469980638 0.863433854115626 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/844 24/18639 0.0416666666666667 0.920171800947867 0.671372469980638 0.863433854115626 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/844 24/18639 0.0416666666666667 0.920171800947867 0.671372469980638 0.863433854115626 GO:0060229 lipase activator activity 1/844 24/18639 0.0416666666666667 0.920171800947867 0.671372469980638 0.863433854115626 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/844 24/18639 0.0416666666666667 0.920171800947867 0.671372469980638 0.863433854115626 GO:0140033 acetylation-dependent protein binding 1/844 24/18639 0.0416666666666667 0.920171800947867 0.671372469980638 0.863433854115626 GO:0015631 tubulin binding 16/844 385/18639 0.0415584415584416 0.917781744322029 0.673804244435152 0.865475376624099 GO:0140034 methylation-dependent protein binding 3/844 76/18639 0.0394736842105263 0.871741706161137 0.675057535396117 0.865999967185257 GO:0005048 signal sequence binding 2/844 51/18639 0.0392156862745098 0.866044047950934 0.678647301143593 0.866115696658033 GO:0005272 sodium channel activity 2/844 51/18639 0.0392156862745098 0.866044047950934 0.678647301143593 0.866115696658033 GO:0001848 complement binding 1/844 25/18639 0.04 0.883364928909953 0.686272369810686 0.866115696658033 GO:0015271 outward rectifier potassium channel activity 1/844 25/18639 0.04 0.883364928909953 0.686272369810686 0.866115696658033 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/844 25/18639 0.04 0.883364928909953 0.686272369810686 0.866115696658033 GO:0017056 structural constituent of nuclear pore 1/844 25/18639 0.04 0.883364928909953 0.686272369810686 0.866115696658033 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/844 25/18639 0.04 0.883364928909953 0.686272369810686 0.866115696658033 GO:0019707 protein-cysteine S-acyltransferase activity 1/844 25/18639 0.04 0.883364928909953 0.686272369810686 0.866115696658033 GO:0047617 fatty acyl-CoA hydrolase activity 1/844 25/18639 0.04 0.883364928909953 0.686272369810686 0.866115696658033 GO:0030159 signaling receptor complex adaptor activity 2/844 52/18639 0.0384615384615385 0.849389354721108 0.688966939689938 0.866115696658033 GO:0004252 serine-type endopeptidase activity 7/844 176/18639 0.0397727272727273 0.878345809995691 0.689660378802459 0.866115696658033 GO:0140104 molecular carrier activity 10/844 249/18639 0.0401606425702811 0.88691257922686 0.695593360806262 0.866115696658033 GO:0001664 G protein-coupled receptor binding 12/844 297/18639 0.0404040404040404 0.89228780697975 0.697935194610036 0.866115696658033 GO:0004864 protein phosphatase inhibitor activity 2/844 53/18639 0.0377358490566038 0.833363140481087 0.699012273158569 0.866115696658033 GO:0034212 protein N-acetyltransferase activity 2/844 53/18639 0.0377358490566038 0.833363140481087 0.699012273158569 0.866115696658033 GO:0033293 monocarboxylic acid binding 3/844 79/18639 0.0379746835443038 0.838637590737297 0.700322649018456 0.866115696658033 GO:0001637 G protein-coupled chemoattractant receptor activity 1/844 26/18639 0.0384615384615385 0.849389354721108 0.700497475638545 0.866115696658033 GO:0004529 DNA exonuclease activity 1/844 26/18639 0.0384615384615385 0.849389354721108 0.700497475638545 0.866115696658033 GO:0004950 chemokine receptor activity 1/844 26/18639 0.0384615384615385 0.849389354721108 0.700497475638545 0.866115696658033 GO:0008143 poly(A) binding 1/844 26/18639 0.0384615384615385 0.849389354721108 0.700497475638545 0.866115696658033 GO:0008198 ferrous iron binding 1/844 26/18639 0.0384615384615385 0.849389354721108 0.700497475638545 0.866115696658033 GO:0015216 purine nucleotide transmembrane transporter activity 1/844 26/18639 0.0384615384615385 0.849389354721108 0.700497475638545 0.866115696658033 GO:0016289 acyl-CoA hydrolase activity 1/844 26/18639 0.0384615384615385 0.849389354721108 0.700497475638545 0.866115696658033 GO:0030247 polysaccharide binding 1/844 26/18639 0.0384615384615385 0.849389354721108 0.700497475638545 0.866115696658033 GO:0043548 phosphatidylinositol 3-kinase binding 1/844 26/18639 0.0384615384615385 0.849389354721108 0.700497475638545 0.866115696658033 GO:0050681 nuclear androgen receptor binding 1/844 26/18639 0.0384615384615385 0.849389354721108 0.700497475638545 0.866115696658033 GO:0051139 metal cation:proton antiporter activity 1/844 26/18639 0.0384615384615385 0.849389354721108 0.700497475638545 0.866115696658033 GO:0052742 phosphatidylinositol kinase activity 1/844 26/18639 0.0384615384615385 0.849389354721108 0.700497475638545 0.866115696658033 GO:0070412 R-SMAD binding 1/844 26/18639 0.0384615384615385 0.849389354721108 0.700497475638545 0.866115696658033 GO:0097602 cullin family protein binding 1/844 26/18639 0.0384615384615385 0.849389354721108 0.700497475638545 0.866115696658033 GO:0005506 iron ion binding 6/844 154/18639 0.038961038961039 0.860420385301902 0.702810695142355 0.867928870507125 GO:0000049 tRNA binding 3/844 80/18639 0.0375 0.828154620853081 0.708404886846567 0.873784607722901 GO:0001671 ATPase activator activity 1/844 27/18639 0.037037037037037 0.817930489731438 0.714078313255322 0.875981305538913 GO:0004364 glutathione transferase activity 1/844 27/18639 0.037037037037037 0.817930489731438 0.714078313255322 0.875981305538913 GO:0008266 poly(U) RNA binding 1/844 27/18639 0.037037037037037 0.817930489731438 0.714078313255322 0.875981305538913 GO:0023026 MHC class II protein complex binding 1/844 27/18639 0.037037037037037 0.817930489731438 0.714078313255322 0.875981305538913 GO:0140375 immune receptor activity 6/844 156/18639 0.0384615384615385 0.849389354721108 0.714458898956616 0.875981305538913 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 5/844 132/18639 0.0378787878787879 0.836519819043516 0.71899174278035 0.880485706511181 GO:0016866 intramolecular transferase activity 1/844 28/18639 0.0357142857142857 0.788718686526743 0.727044029116729 0.881475859604627 GO:0019789 SUMO transferase activity 1/844 28/18639 0.0357142857142857 0.788718686526743 0.727044029116729 0.881475859604627 GO:0036408 histone H3K14 acetyltransferase activity 1/844 28/18639 0.0357142857142857 0.788718686526743 0.727044029116729 0.881475859604627 GO:0046625 sphingolipid binding 1/844 28/18639 0.0357142857142857 0.788718686526743 0.727044029116729 0.881475859604627 GO:0051393 alpha-actinin binding 1/844 28/18639 0.0357142857142857 0.788718686526743 0.727044029116729 0.881475859604627 GO:0051959 dynein light intermediate chain binding 1/844 28/18639 0.0357142857142857 0.788718686526743 0.727044029116729 0.881475859604627 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 1/844 28/18639 0.0357142857142857 0.788718686526743 0.727044029116729 0.881475859604627 GO:0019212 phosphatase inhibitor activity 2/844 56/18639 0.0357142857142857 0.788718686526743 0.727540075341966 0.881475859604627 GO:0030170 pyridoxal phosphate binding 2/844 56/18639 0.0357142857142857 0.788718686526743 0.727540075341966 0.881475859604627 GO:0070279 vitamin B6 binding 2/844 57/18639 0.0350877192982456 0.774881516587678 0.736526869036517 0.890591900463018 GO:0015079 potassium ion transmembrane transporter activity 6/844 160/18639 0.0375 0.828154620853081 0.736801884480624 0.890591900463018 GO:0004860 protein kinase inhibitor activity 3/844 84/18639 0.0357142857142857 0.788718686526743 0.739060908445282 0.890608712002123 GO:0010484 histone H3 acetyltransferase activity 1/844 29/18639 0.0344827586206897 0.761521490439614 0.739422452598836 0.890608712002123 GO:0051861 glycolipid binding 1/844 29/18639 0.0344827586206897 0.761521490439614 0.739422452598836 0.890608712002123 GO:0017116 single-stranded DNA helicase activity 2/844 58/18639 0.0344827586206897 0.761521490439614 0.74525965388212 0.891103287446834 GO:0001965 G-protein alpha-subunit binding 1/844 30/18639 0.0333333333333333 0.736137440758294 0.751240155447121 0.891103287446834 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/844 30/18639 0.0333333333333333 0.736137440758294 0.751240155447121 0.891103287446834 GO:0008187 poly-pyrimidine tract binding 1/844 30/18639 0.0333333333333333 0.736137440758294 0.751240155447121 0.891103287446834 GO:0031624 ubiquitin conjugating enzyme binding 1/844 30/18639 0.0333333333333333 0.736137440758294 0.751240155447121 0.891103287446834 GO:0033612 receptor serine/threonine kinase binding 1/844 30/18639 0.0333333333333333 0.736137440758294 0.751240155447121 0.891103287446834 GO:0043995 histone H4K5 acetyltransferase activity 1/844 30/18639 0.0333333333333333 0.736137440758294 0.751240155447121 0.891103287446834 GO:0043996 histone H4K8 acetyltransferase activity 1/844 30/18639 0.0333333333333333 0.736137440758294 0.751240155447121 0.891103287446834 GO:0043997 histone H4K12 acetyltransferase activity 1/844 30/18639 0.0333333333333333 0.736137440758294 0.751240155447121 0.891103287446834 GO:0048019 receptor antagonist activity 1/844 30/18639 0.0333333333333333 0.736137440758294 0.751240155447121 0.891103287446834 GO:0051721 protein phosphatase 2A binding 1/844 30/18639 0.0333333333333333 0.736137440758294 0.751240155447121 0.891103287446834 GO:0098918 structural constituent of synapse 1/844 30/18639 0.0333333333333333 0.736137440758294 0.751240155447121 0.891103287446834 GO:0140597 protein carrier chaperone 7/844 188/18639 0.0372340425531915 0.822281183825754 0.752718893869689 0.891103287446834 GO:0036002 pre-mRNA binding 2/844 59/18639 0.0338983050847458 0.748614346533858 0.753742975820883 0.891103287446834 GO:0045309 protein phosphorylated amino acid binding 2/844 59/18639 0.0338983050847458 0.748614346533858 0.753742975820883 0.891103287446834 GO:0070063 RNA polymerase binding 2/844 59/18639 0.0338983050847458 0.748614346533858 0.753742975820883 0.891103287446834 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 2/844 60/18639 0.0333333333333333 0.736137440758294 0.761981490267671 0.89734279134197 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2/844 60/18639 0.0333333333333333 0.736137440758294 0.761981490267671 0.89734279134197 GO:0047499 calcium-independent phospholipase A2 activity 1/844 31/18639 0.032258064516129 0.712391071701575 0.762522508545225 0.89734279134197 GO:0070273 phosphatidylinositol-4-phosphate binding 1/844 31/18639 0.032258064516129 0.712391071701575 0.762522508545225 0.89734279134197 GO:0001221 transcription coregulator binding 4/844 115/18639 0.0347826086956522 0.768143416443437 0.770327494525875 0.903792565025325 GO:0016874 ligase activity 6/844 167/18639 0.0359281437125748 0.793441552913131 0.772846536825064 0.903792565025325 GO:0030515 snoRNA binding 1/844 32/18639 0.03125 0.6901288507109 0.773293736124107 0.903792565025325 GO:0031369 translation initiation factor binding 1/844 32/18639 0.03125 0.6901288507109 0.773293736124107 0.903792565025325 GO:0047498 calcium-dependent phospholipase A2 activity 1/844 32/18639 0.03125 0.6901288507109 0.773293736124107 0.903792565025325 GO:0070717 poly-purine tract binding 1/844 32/18639 0.03125 0.6901288507109 0.773293736124107 0.903792565025325 GO:0019210 kinase inhibitor activity 3/844 90/18639 0.0333333333333333 0.736137440758294 0.780179005154151 0.910801230390666 GO:0140297 DNA-binding transcription factor binding 19/844 488/18639 0.0389344262295082 0.859832666459483 0.782937351936489 0.911653112048858 GO:0071889 14-3-3 protein binding 1/844 33/18639 0.0303030303030303 0.669215855234813 0.783576967526872 0.911653112048858 GO:0140311 protein sequestering activity 1/844 33/18639 0.0303030303030303 0.669215855234813 0.783576967526872 0.911653112048858 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 1/844 34/18639 0.0294117647058824 0.6495330359632 0.79339428663938 0.919942470368059 GO:0030332 cyclin binding 1/844 34/18639 0.0294117647058824 0.6495330359632 0.79339428663938 0.919942470368059 GO:0051427 hormone receptor binding 1/844 34/18639 0.0294117647058824 0.6495330359632 0.79339428663938 0.919942470368059 GO:0005244 voltage-gated monoatomic ion channel activity 6/844 173/18639 0.0346820809248555 0.765923348765855 0.800695655833393 0.925481025321993 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 13/844 349/18639 0.0372492836676218 0.822617770474884 0.802129993174428 0.925481025321993 GO:0004623 phospholipase A2 activity 1/844 35/18639 0.0285714285714286 0.630974949221395 0.802766779091751 0.925481025321993 GO:0005154 epidermal growth factor receptor binding 1/844 35/18639 0.0285714285714286 0.630974949221395 0.802766779091751 0.925481025321993 GO:0043015 gamma-tubulin binding 1/844 35/18639 0.0285714285714286 0.630974949221395 0.802766779091751 0.925481025321993 GO:0016410 N-acyltransferase activity 3/844 94/18639 0.0319148936170213 0.704812443279217 0.804512636509569 0.925481025321993 GO:0022832 voltage-gated channel activity 6/844 175/18639 0.0342857142857143 0.757169939065674 0.809369527090772 0.925481025321993 GO:0008276 protein methyltransferase activity 3/844 95/18639 0.0315789473684211 0.69739336492891 0.810230133283383 0.925481025321993 GO:0000993 RNA polymerase II complex binding 1/844 36/18639 0.0277777777777778 0.613447867298578 0.811714577331192 0.925481025321993 GO:0004033 aldo-keto reductase (NADPH) activity 1/844 36/18639 0.0277777777777778 0.613447867298578 0.811714577331192 0.925481025321993 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/844 36/18639 0.0277777777777778 0.613447867298578 0.811714577331192 0.925481025321993 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 1/844 36/18639 0.0277777777777778 0.613447867298578 0.811714577331192 0.925481025321993 GO:0016409 palmitoyltransferase activity 1/844 36/18639 0.0277777777777778 0.613447867298578 0.811714577331192 0.925481025321993 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/844 36/18639 0.0277777777777778 0.613447867298578 0.811714577331192 0.925481025321993 GO:0045505 dynein intermediate chain binding 1/844 36/18639 0.0277777777777778 0.613447867298578 0.811714577331192 0.925481025321993 GO:0042054 histone methyltransferase activity 2/844 67/18639 0.0298507462686567 0.659227558888024 0.813202321189503 0.926147088021379 GO:0030280 structural constituent of skin epidermis 1/844 37/18639 0.027027027027027 0.596868195209427 0.820256903662024 0.932077293225141 GO:0042805 actinin binding 1/844 37/18639 0.027027027027027 0.596868195209427 0.820256903662024 0.932077293225141 GO:0000287 magnesium ion binding 8/844 230/18639 0.0347826086956522 0.768143416443437 0.822728794740752 0.932077293225141 GO:0003924 GTPase activity 12/844 331/18639 0.0362537764350453 0.800632866081528 0.822941404381757 0.932077293225141 GO:0016279 protein-lysine N-methyltransferase activity 2/844 69/18639 0.0289855072463768 0.640119513702864 0.825911835320286 0.932077293225141 GO:0008170 N-methyltransferase activity 3/844 98/18639 0.0306122448979592 0.676044588451494 0.826540315297578 0.932077293225141 GO:0003774 cytoskeletal motor activity 5/844 153/18639 0.0326797385620915 0.721703373292445 0.827806828738358 0.932077293225141 GO:0005501 retinoid binding 1/844 38/18639 0.0263157894736842 0.581161137440758 0.828412111344491 0.932077293225141 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 1/844 38/18639 0.0263157894736842 0.581161137440758 0.828412111344491 0.932077293225141 GO:0019840 isoprenoid binding 1/844 38/18639 0.0263157894736842 0.581161137440758 0.828412111344491 0.932077293225141 GO:0042162 telomeric DNA binding 1/844 38/18639 0.0263157894736842 0.581161137440758 0.828412111344491 0.932077293225141 GO:0016278 lysine N-methyltransferase activity 2/844 70/18639 0.0285714285714286 0.630974949221395 0.831970464149552 0.934561014093073 GO:0042826 histone deacetylase binding 4/844 127/18639 0.031496062992126 0.695562936149569 0.832443127675098 0.934561014093073 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 1/844 39/18639 0.0256410256410256 0.566259569814072 0.836197723839801 0.937749088551199 GO:0004532 RNA exonuclease activity 1/844 40/18639 0.025 0.55210308056872 0.843630472284919 0.942696745468979 GO:0061791 GTPase motor activity 1/844 40/18639 0.025 0.55210308056872 0.843630472284919 0.942696745468979 GO:1990606 membrane scission GTPase motor activity 1/844 40/18639 0.025 0.55210308056872 0.843630472284919 0.942696745468979 GO:0140658 ATP-dependent chromatin remodeler activity 5/844 158/18639 0.0316455696202532 0.698864658947747 0.847953011673507 0.942696745468979 GO:0004521 RNA endonuclease activity 2/844 73/18639 0.0273972602739726 0.605044471856132 0.849020266326581 0.942696745468979 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 2/844 73/18639 0.0273972602739726 0.605044471856132 0.849020266326581 0.942696745468979 GO:0001727 lipid kinase activity 1/844 41/18639 0.024390243902439 0.538637151774361 0.850726331276883 0.942696745468979 GO:0004812 aminoacyl-tRNA ligase activity 1/844 41/18639 0.024390243902439 0.538637151774361 0.850726331276883 0.942696745468979 GO:0008227 G protein-coupled amine receptor activity 1/844 41/18639 0.024390243902439 0.538637151774361 0.850726331276883 0.942696745468979 GO:0016875 ligase activity, forming carbon-oxygen bonds 1/844 41/18639 0.024390243902439 0.538637151774361 0.850726331276883 0.942696745468979 GO:0140828 metal cation:monoatomic cation antiporter activity 1/844 41/18639 0.024390243902439 0.538637151774361 0.850726331276883 0.942696745468979 GO:0003678 DNA helicase activity 2/844 74/18639 0.027027027027027 0.596868195209427 0.854344147628309 0.944663162156437 GO:0031491 nucleosome binding 2/844 74/18639 0.027027027027027 0.596868195209427 0.854344147628309 0.944663162156437 GO:0042056 chemoattractant activity 1/844 42/18639 0.0238095238095238 0.525812457684496 0.857500553042788 0.944802010274044 GO:0043175 RNA polymerase core enzyme binding 1/844 42/18639 0.0238095238095238 0.525812457684496 0.857500553042788 0.944802010274044 GO:0051879 Hsp90 protein binding 1/844 42/18639 0.0238095238095238 0.525812457684496 0.857500553042788 0.944802010274044 GO:0046982 protein heterodimerization activity 13/844 369/18639 0.035230352303523 0.778031441451855 0.858156752746473 0.944802010274044 GO:0019003 GDP binding 2/844 75/18639 0.0266666666666667 0.588909952606635 0.859496190967321 0.945261368821357 GO:0005245 voltage-gated calcium channel activity 1/844 43/18639 0.0232558139534884 0.513584260994159 0.863967700068217 0.948144424593064 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/844 43/18639 0.0232558139534884 0.513584260994159 0.863967700068217 0.948144424593064 GO:0003724 RNA helicase activity 2/844 77/18639 0.025974025974026 0.573613590201268 0.869303190570257 0.951862559402227 GO:0001223 transcription coactivator binding 1/844 44/18639 0.0227272727272727 0.501911891426109 0.870141676253548 0.951862559402227 GO:0030547 signaling receptor inhibitor activity 1/844 44/18639 0.0227272727272727 0.501911891426109 0.870141676253548 0.951862559402227 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1/844 45/18639 0.0222222222222222 0.490758293838863 0.876035756664519 0.957288540065173 GO:0008186 ATP-dependent activity, acting on RNA 2/844 79/18639 0.0253164556962025 0.559091727158198 0.87847744009891 0.958934372844923 GO:0008017 microtubule binding 9/844 276/18639 0.0326086956521739 0.720134452915722 0.882457840452066 0.962254560067413 GO:0030971 receptor tyrosine kinase binding 2/844 81/18639 0.0246913580246914 0.545286993154292 0.887053959615836 0.965847531907059 GO:0043022 ribosome binding 3/844 112/18639 0.0267857142857143 0.591539014895058 0.887637439079463 0.965847531907059 GO:0016879 ligase activity, forming carbon-nitrogen bonds 1/844 48/18639 0.0208333333333333 0.460085900473934 0.892162529044516 0.969741879396213 GO:0140030 modification-dependent protein binding 5/844 173/18639 0.0289017341040462 0.638269457304879 0.896974707184006 0.973939697948735 GO:0004527 exonuclease activity 2/844 84/18639 0.0238095238095238 0.525812457684496 0.89887155045652 0.974966496526913 GO:0050660 flavin adenine dinucleotide binding 2/844 86/18639 0.0232558139534884 0.513584260994159 0.906098726331547 0.981606631025557 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 1/844 52/18639 0.0192307692307692 0.424694677360554 0.910452839074803 0.981606631025557 GO:0003730 mRNA 3'-UTR binding 8/844 262/18639 0.0305343511450382 0.674324373213704 0.911052445201794 0.981606631025557 GO:0005246 calcium channel regulator activity 1/844 53/18639 0.0188679245283019 0.416681570240544 0.914519003803961 0.981606631025557 GO:0000510 H3-H4 histone complex chaperone activity 4/844 151/18639 0.0264900662251656 0.585009886695333 0.915224225155065 0.981606631025557 GO:0140584 chromatin extrusion motor activity 4/844 151/18639 0.0264900662251656 0.585009886695333 0.915224225155065 0.981606631025557 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 4/844 151/18639 0.0264900662251656 0.585009886695333 0.915224225155065 0.981606631025557 GO:0140849 ATP-dependent H2AZ histone chaperone activity 4/844 151/18639 0.0264900662251656 0.585009886695333 0.915224225155065 0.981606631025557 GO:0004540 RNA nuclease activity 3/844 121/18639 0.0247933884297521 0.547540245192119 0.91597091860279 0.981606631025557 GO:0003727 single-stranded RNA binding 2/844 89/18639 0.0224719101123595 0.496272431971883 0.916038904249377 0.981606631025557 GO:0015616 DNA translocase activity 4/844 152/18639 0.0263157894736842 0.581161137440758 0.91770250745201 0.981606631025557 GO:0140674 ATP-dependent histone chaperone activity 4/844 152/18639 0.0263157894736842 0.581161137440758 0.91770250745201 0.981606631025557 GO:0008094 ATP-dependent activity, acting on DNA 6/844 210/18639 0.0285714285714286 0.630974949221395 0.918041080874697 0.981606631025557 GO:0050661 NADP binding 1/844 54/18639 0.0185185185185185 0.408965244865719 0.91840074063757 0.981606631025557 GO:0061775 cohesin loader activity 4/844 153/18639 0.0261437908496732 0.577362698633956 0.920115814263115 0.982415322520513 GO:0005267 potassium channel activity 3/844 124/18639 0.0241935483870968 0.534293303776181 0.92386256641809 0.985314547672236 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/844 56/18639 0.0178571428571429 0.394359343263372 0.925643974779498 0.985314547672236 GO:0015078 proton transmembrane transporter activity 5/844 185/18639 0.027027027027027 0.596868195209427 0.925715033569135 0.985314547672236 GO:0004519 endonuclease activity 3/844 127/18639 0.0236220472440945 0.521672202112177 0.931070189501589 0.989986456679594 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 3/844 128/18639 0.0234375 0.517596638033175 0.933329703947832 0.991360566369459 GO:0003689 DNA clamp loader activity 4/844 160/18639 0.025 0.55210308056872 0.935304210498956 0.991422580033505 GO:0031593 polyubiquitin modification-dependent protein binding 1/844 59/18639 0.0169491525423729 0.374307173266929 0.935322570626731 0.991422580033505 GO:0030594 neurotransmitter receptor activity 2/844 97/18639 0.0206185567010309 0.4553427468608 0.937925205842015 0.991460895789264 GO:0001098 basal transcription machinery binding 1/844 60/18639 0.0166666666666667 0.368068720379147 0.938260555039596 0.991460895789264 GO:0001099 basal RNA polymerase II transcription machinery binding 1/844 60/18639 0.0166666666666667 0.368068720379147 0.938260555039596 0.991460895789264 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/844 61/18639 0.0163934426229508 0.362034806930308 0.941065231908458 0.993142795141984 GO:0140097 catalytic activity, acting on DNA 10/844 336/18639 0.0297619047619048 0.657265572105619 0.942608969593362 0.993142795141984 GO:0140713 histone chaperone activity 4/844 164/18639 0.024390243902439 0.538637151774361 0.942758965534781 0.993142795141984 GO:0022824 transmitter-gated monoatomic ion channel activity 1/844 63/18639 0.0158730158730159 0.35054163845633 0.946298556779008 0.99433653292182 GO:0022835 transmitter-gated channel activity 1/844 63/18639 0.0158730158730159 0.35054163845633 0.946298556779008 0.99433653292182 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 4/844 167/18639 0.0239520958083832 0.528961035275421 0.94782644865866 0.99433653292182 GO:0016779 nucleotidyltransferase activity 3/844 136/18639 0.0220588235294118 0.4871497769724 0.949089987549707 0.99433653292182 GO:0004722 protein serine/threonine phosphatase activity 2/844 103/18639 0.0194174757281553 0.428817926655317 0.950663138943557 0.99433653292182 GO:0160215 deacylase activity 1/844 65/18639 0.0153846153846154 0.339755741888443 0.951067671225228 0.99433653292182 GO:0140767 enzyme-substrate adaptor activity 3/844 139/18639 0.0215827338129496 0.476635753008967 0.954048702063471 0.99433653292182 GO:0008173 RNA methyltransferase activity 1/844 67/18639 0.0149253731343284 0.329613779444012 0.955413707505267 0.99433653292182 GO:0005125 cytokine activity 6/844 234/18639 0.0256410256410256 0.566259569814072 0.956813367181235 0.99433653292182 GO:0008168 methyltransferase activity 5/844 204/18639 0.0245098039215686 0.541277529969334 0.956839120230311 0.99433653292182 GO:0003777 microtubule motor activity 1/844 68/18639 0.0147058823529412 0.3247665179816 0.957439920668392 0.99433653292182 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 1/844 68/18639 0.0147058823529412 0.3247665179816 0.957439920668392 0.99433653292182 GO:0140223 general transcription initiation factor activity 1/844 68/18639 0.0147058823529412 0.3247665179816 0.957439920668392 0.99433653292182 GO:0002039 p53 binding 1/844 69/18639 0.0144927536231884 0.320059756851432 0.959374157217629 0.99433653292182 GO:0098960 postsynaptic neurotransmitter receptor activity 1/844 69/18639 0.0144927536231884 0.320059756851432 0.959374157217629 0.99433653292182 GO:0022843 voltage-gated monoatomic cation channel activity 3/844 143/18639 0.020979020979021 0.463303284393332 0.95996024564058 0.99433653292182 GO:0004518 nuclease activity 5/844 209/18639 0.0239234449760766 0.528328306764326 0.962759478281614 0.99433653292182 GO:0003684 damaged DNA binding 1/844 74/18639 0.0135135135135135 0.298434097604714 0.967805220687332 0.99433653292182 GO:0016741 transferase activity, transferring one-carbon groups 5/844 215/18639 0.0232558139534884 0.513584260994159 0.968875775272916 0.99433653292182 GO:0019001 guanyl nucleotide binding 11/844 400/18639 0.0275 0.607313388625592 0.975035605883733 0.99433653292182 GO:0032561 guanyl ribonucleotide binding 11/844 400/18639 0.0275 0.607313388625592 0.975035605883733 0.99433653292182 GO:0003697 single-stranded DNA binding 2/844 121/18639 0.0165289256198347 0.36502683012808 0.975568139010914 0.99433653292182 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 2/844 122/18639 0.0163934426229508 0.362034806930308 0.976516261979498 0.99433653292182 GO:0033192 calmodulin-dependent protein phosphatase activity 1/844 81/18639 0.0123456790123457 0.272643496577146 0.976755781254365 0.99433653292182 GO:0140791 histone H2AXS140 phosphatase activity 1/844 81/18639 0.0123456790123457 0.272643496577146 0.976755781254365 0.99433653292182 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/844 81/18639 0.0123456790123457 0.272643496577146 0.976755781254365 0.99433653292182 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/844 81/18639 0.0123456790123457 0.272643496577146 0.976755781254365 0.99433653292182 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/844 81/18639 0.0123456790123457 0.272643496577146 0.976755781254365 0.99433653292182 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/844 81/18639 0.0123456790123457 0.272643496577146 0.976755781254365 0.99433653292182 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/844 81/18639 0.0123456790123457 0.272643496577146 0.976755781254365 0.99433653292182 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/844 81/18639 0.0123456790123457 0.272643496577146 0.976755781254365 0.99433653292182 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/844 82/18639 0.0121951219512195 0.269318575887181 0.977812905978006 0.99433653292182 GO:0033549 MAP kinase phosphatase activity 1/844 82/18639 0.0121951219512195 0.269318575887181 0.977812905978006 0.99433653292182 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/844 83/18639 0.0120481927710843 0.266073773768058 0.978822008061024 0.99433653292182 GO:0008135 translation factor activity, RNA binding 1/844 83/18639 0.0120481927710843 0.266073773768058 0.978822008061024 0.99433653292182 GO:0017018 myosin phosphatase activity 1/844 84/18639 0.0119047619047619 0.262906228842248 0.979785266586379 0.99433653292182 GO:0180051 translation factor activity 1/844 84/18639 0.0119047619047619 0.262906228842248 0.979785266586379 0.99433653292182 GO:0005126 cytokine receptor binding 6/844 275/18639 0.0218181818181818 0.481835415769065 0.986826887802831 0.999996480661486 GO:0005249 voltage-gated potassium channel activity 1/844 98/18639 0.0102040816326531 0.225348196150498 0.989467870036283 0.999996480661486 GO:0005525 GTP binding 9/844 378/18639 0.0238095238095238 0.525812457684496 0.990135242699094 0.999996480661486 GO:0046906 tetrapyrrole binding 2/844 152/18639 0.0131578947368421 0.290580568720379 0.992987727260103 0.999996480661486 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 12/844 484/18639 0.0247933884297521 0.547540245192119 0.993578375999524 0.999996480661486 GO:0001216 DNA-binding transcription activator activity 12/844 491/18639 0.0244399185336049 0.539734172450073 0.994636822803387 0.999996480661486 GO:0008528 G protein-coupled peptide receptor activity 1/844 122/18639 0.00819672131147541 0.181017403465154 0.996559642696786 0.999996480661486 GO:0003823 antigen binding 2/844 174/18639 0.0114942528735632 0.253840496813205 0.997171019368737 0.999996480661486 GO:0001653 peptide receptor activity 1/844 128/18639 0.0078125 0.172532212677725 0.997399692850786 0.999996480661486 GO:0031490 chromatin DNA binding 1/844 128/18639 0.0078125 0.172532212677725 0.997399692850786 0.999996480661486 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/844 130/18639 0.00769230769230769 0.169877870944222 0.997631412758552 0.999996480661486 GO:0140101 catalytic activity, acting on a tRNA 1/844 139/18639 0.00719424460431655 0.158878584336322 0.998443944110108 0.999996480661486 GO:0140098 catalytic activity, acting on RNA 7/844 387/18639 0.0180878552971576 0.399454425217679 0.998896624688566 0.999996480661486 GO:0045182 translation regulator activity 5/844 356/18639 0.0140449438202247 0.310170269982427 0.999732856580739 0.999996480661486 GO:0030371 translation repressor activity 2/844 329/18639 0.0060790273556231 0.134249989196041 0.999996480661486 0.999996480661486