category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	16/233	89/9376	7.23421902878912	LAMA5/COL4A2/ITGB4/LAMB1/ITGA6/FRAS1/LAMC1/ITGB1/ITGB5/DAG1/COL4A1/FREM2/ITGB8/LAMB4/COL6A1/HSPG2	9.43318986658924
NA	NA	hsa04518	Integrin signaling	20/233	154/9376	5.22601861657656	FBN1/CDH1/EGFR/LAMA5/COL4A2/ITGB4/LAMB1/MET/ITGA6/FRAS1/LAMC1/ITGB1/ITGB5/COL4A1/FERMT1/FREM2/ITGB8/LAMB4/COL6A1/IGF1R	8.44108835556347
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	22/233	233/9376	3.7995173976312	FBN2/FBN1/FBLN1/COL4A2/ITGB4/ITGA6/DSG2/ITGB1/DSP/MYH10/SYNE2/ITGB5/DAG1/COL4A1/ANK3/BGN/ITGB8/COL6A1/DMD/COL5A2/HSPG2/PKP2	6.9077404359
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	22/233	238/9376	3.71969560356331	RPL39/RPS29/RPL37A/RPS28/RPS27/RPL36/EGFR/RPL37/RPLP2/RPS17/NRP1/RPL12/RPLP1/C1QB/RPL21/RPSA/C1QA/RPL34/RPS21/RPS15A/RPL38/RPLP0	6.78425931653993
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	15/233	138/9376	4.37395036387386	MT-ND3/MT-ND6/MT-ND4L/UQCR11/UQCRQ/NDUFB1/COX6C/UQCRB/ATP6V1B1/NDUFA3/MT-CO2/MT-ND4/COX7B/COX7C/UQCR10	6.37394764968885
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	11/233	86/9376	5.14702066074458	ITGB4/ITGA6/DSG2/ITGB1/GJA1/DSP/ITGB5/DAG1/ITGB8/DMD/PKP2	6.16732459427603
Genetic Information Processing	Translation	hsa03010	Ribosome	18/233	222/9376	3.2627305417005	RPL39/RPS29/RPL37A/RPS28/RPS27/RPL36/RPL37/RPLP2/RPS17/RPL12/RPLP1/RPL21/RPSA/RPL34/RPS21/RPS15A/RPL38/RPLP0	5.44657026680602
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	18/233	227/9376	3.1908642302093	MT-ND3/MT-ND6/MT-ND4L/EGFR/MET/UQCR11/SLC26A2/UQCRQ/NDUFB1/COX6C/UQCRB/NDUFA3/MT-CO2/MGST3/MT-ND4/COX7B/COX7C/UQCR10	5.33409588704122
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	23/233	362/9376	2.5567068977782	EGFR/LAMA5/COL4A2/ITGB4/LAMB1/MET/ITGA6/LAMC1/ITGB1/ERBB3/GNG12/ITGB5/HSP90B1/COL4A1/CSF3R/ITGB8/GHR/CDK6/EFNA1/LAMB4/COL6A1/FGFR2/IGF1R	4.82193772294331
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	16/233	205/9376	3.14070972469381	MT-ND3/MT-ND6/MT-ND4L/UQCR11/UQCRQ/NDUFB1/COX6C/UQCRB/SLC2A1/NDUFA3/MT-CO2/PRKCZ/MT-ND4/COX7B/COX7C/UQCR10	4.94704208068835
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	15/233	184/9376	3.28046277290539	SEMA6D/SEMA6A/BMP7/MET/NRP1/ITGB1/PLXNB1/EPHB4/PRKCZ/SEMA3F/PARD3/FZD3/EFNA1/RASA1/SEMA7A	4.98707764090989
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	21/233	333/9376	2.5376793102115	EGFR/LAMA5/COL4A2/ITGB4/LAMB1/ITGA6/LAMC1/ITGB1/NOTCH3/ITGB5/ATP6V1B1/COL4A1/PRKCZ/DLG3/PARD3/FZD3/ITGB8/CDK6/LAMB4/COL6A1/PRKACB	4.56090326420715
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	15/233	203/9376	2.97342438529356	EGFR/LAMA5/COL4A2/ITGB4/LAMB1/MET/ITGA6/LAMC1/ITGB1/ITGB5/COL4A1/ITGB8/LAMB4/COL6A1/IGF1R	4.5376610417022
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	18/233	275/9376	2.63391338275458	MT-ND3/MT-ND6/MT-ND4L/UQCR11/LAMC1/UQCRQ/NDUFB1/COX6C/C1QB/UQCRB/C1QA/NDUFA3/MT-CO2/MT-ND4/COX7B/COX7C/UQCR10/PRKACB	4.39005598286667
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	22/233	388/9376	2.28166895270121	MT-ND3/MT-ND6/MT-ND4L/UQCR11/LRP5/UQCRQ/NDUFB1/MME/COX6C/APOE/LRP1/UQCRB/NDUFA3/MT-CO2/MT-ND4/COX7B/COX7C/FZD3/LPL/UQCR10/APP/SLC39A10	4.11603855161248
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	17/233	268/9376	2.55255909294728	MT-ND3/MT-ND6/MT-ND4L/UQCR11/UQCRQ/NDUFB1/COX6C/UQCRB/NDUFA3/MT-CO2/MT-ND4/COX7B/COX7C/UQCR10/SLC39A10/GPR37/PRKACB	4.1164539745697
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	9/233	93/9376	3.89422677557801	LAMA5/COL4A2/LAMB1/ITGA6/LAMC1/ITGB1/COL4A1/CDK6/LAMB4	4.47763918875987
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	12/233	157/9376	3.0756950329406	CDH1/BMP7/DLG5/RASSF6/FRMD6/PRKCZ/DLG3/PARD3/FZD3/TEAD1/BMPR1A/BMP4	4.18688183024725
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	14/233	204/9376	2.76159219052428	EGFR/MET/TIMP3/CTSL/ITGB1/ERBB3/ITGB5/ANK3/GPC1/GPC3/FZD3/PRKACB/HSPG2/IGF1R	4.06076330401451
NA	NA	hsa03273	Virion - Lassa virus and SFTS virus	4/233	17/9376	9.46831608179752	MYH10/TFRC/DAG1/PCDH11X	5.57861044541832
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	15/233	235/9376	2.56853255410465	MT-ND3/MT-ND6/MT-ND4L/UQCR11/UQCRQ/NDUFB1/COX6C/UQCRB/NDUFA3/MT-CO2/MT-ND4/COX7B/COX7C/UQCR10/PRKACB	3.88731605648617
NA	NA	hsa04382	Cornified envelope formation	14/233	217/9376	2.59615118371868	LAMA5/COL4A2/ITGB4/ITGA6/DSG2/CLDN4/KRT80/PRSS8/DSP/KRT7/COL4A1/CLDN3/KRT8/PKP2	3.79751152498566
NA	NA	hsa04519	Cadherin signaling	21/233	404/9376	2.09170101559512	CDH1/EGFR/MET/DSC3/DSG2/GABRE/LRP5/KRT80/GJA1/DSP/FAT1/KRT7/TMC5/MYO7A/PCDH11X/FZD3/NCKAP1/TEAD1/KRT8/IGF1R/PKP2	3.58070879724155
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	9/233	105/9376	3.44917228694053	ITGB4/ITGA6/ADRB1/ITGB1/ITGB5/DAG1/ITGB8/PRKACB/DMD	4.02874643720778
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	8/233	87/9376	3.70026145725421	UQCR11/UQCRQ/COX6C/UQCRB/MT-CO2/COX7B/COX7C/UQCR10	4.03924504756233
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	17/233	308/9376	2.22105791204504	MT-ND3/MT-ND6/MT-ND4L/UQCR11/POLR2L/UQCRQ/NDUFB1/COX6C/UQCRB/CLTC/NDUFA3/GPX8/MT-CO2/MT-ND4/COX7B/COX7C/UQCR10	3.47836460698833
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	6/233	52/9376	4.64311654011225	LRP2/APOC1/LIPA/APOE/LRP1/LPL	4.20525990466507
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	11/233	160/9376	2.76652360515021	CDH1/PTPRF/ITGA6/CLDN4/ITGB1/JAM3/ITGB8/CLDN3/CADM1/NRCAM/NRXN3	3.59772067700015
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	8/233	93/9376	3.4615349116249	CDH1/EGFR/PTPRF/MET/SORBS1/PARD3/LMO7/IGF1R	3.80822445490334
NA	NA	hsa04517	IgSF CAM signaling	16/233	299/9376	2.15332940990713	CDH1/PTPRF/NRP1/ITGB1/MYH10/JAM3/SORBS1/ANK3/PARD3/LMO7/APP/GLDN/CADM1/RASA1/NRCAM/GRIP1	3.23546742714917
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	8/233	103/9376	3.12546356098171	COL14A1/COL4A2/COL21A1/DPP4/MME/COL4A1/COL6A1/COL5A2	3.46243305408034
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	10/233	157/9376	2.56307919411716	UQCR11/UQCRQ/NDUFB1/COX6C/UQCRB/NDUFA3/MT-CO2/COX7B/COX7C/UQCR10	3.15288506896666
NA	NA	hsa03272	Virion - Hepatitis viruses	5/233	48/9376	4.19170243204578	EGFR/DPP4/CLDN4/CLDN3/HSPG2	3.5388974947535
Cellular Processes	Cellular community - eukaryotes	hsa04530	Tight junction	10/233	170/9376	2.36707902044938	CLDN4/ITGB1/MYH10/JAM3/PRKCZ/DLG3/PARD3/CLDN3/PRKACB/MARVELD2	2.87145379778578
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	7/233	99/9376	2.84527680235835	ITGB4/ITGA6/ITGB1/ITGB5/DAG1/ITGB8/DMD	2.9464194988381
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	9/233	149/9376	2.4306247659648	MT-ND3/MT-ND6/MT-ND4L/GABRE/NDUFB1/GNG12/NDUFA3/MT-ND4/PRKACB	2.81000991114864
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	7/233	103/9376	2.73478061585899	LAMA5/COL4A2/LAMB1/LAMC1/COL4A1/LAMB4/PRKACB	2.82600081045554
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	9/233	155/9376	2.33653606534681	CTSL/ITGB1/MSR1/TFRC/ITGB5/ATP6V1B1/PLA2R1/MRC1/COLEC12	2.67840815882232
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	7/233	106/9376	2.65738116446676	EGFR/SPINT1/HSP90B1/FOLR1/SLC19A1/FGFR2/IGF1R	2.73939528122065
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	16/233	368/9376	1.74958014554954	MT-ND3/MT-ND6/MT-ND4L/UQCR11/UQCRQ/NDUFB1/COX6C/UQCRB/NDUFA3/GPX8/MT-CO2/MT-ND4/COX7B/COX7C/UQCR10/PFN2	2.34178507680204
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	8/233	144/9376	2.23557463042442	ISL1/TBX3/FZD3/LIFR/BMPR1A/FGFR2/BMP4/IGF1R	2.3851822540048
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	19/233	480/9376	1.5928469241774	MT-ND3/MT-ND6/MT-ND4L/UQCR11/LRP5/UQCRQ/NDUFB1/COX6C/UQCRB/NDUFA3/GPX8/MT-CO2/MT-ND4/COX7B/COX7C/FZD3/UQCR10/APP/GPR37	2.12855580840764
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	11/233	232/9376	1.9079473138967	EGFR/ITGB4/ITGA6/ITGB1/MYH10/GNG12/ITGB5/NCKAP1/ITGB8/PFN2/FGFR2	2.23540269777006
Human Diseases	Cancer: overview	hsa05230	Central carbon metabolism in cancer	5/233	71/9376	2.83382699631264	EGFR/MET/SLC2A1/IDH1/FGFR2	2.47598828933883
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	9/233	178/9376	2.03462410184694	LGR5/LGR4/LRP5/RNF43/MMP7/NOTUM/FZD3/ZNRF3/PRKACB	2.22466759364711
Environmental Information Processing	Signal transduction	hsa04392	Hippo signaling pathway - multiple species	3/233	29/9376	4.16279413941098	RASSF6/FRMD6/TEAD1	2.72303386090146
Human Diseases	Cancer: specific types	hsa05218	Melanoma	5/233	73/9376	2.75618790052325	CDH1/EGFR/MET/CDK6/IGF1R	2.40458503043362
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	10/233	212/9376	1.89812940319054	CDH1/EGFR/MET/ITGB1/PRKCZ/PARD3/EFNA1/PFN2/FGFR2/IGF1R	2.11146333151175
NA	NA	hsa04981	Folate transport and metabolism	3/233	31/9376	3.89422677557801	SLCO2B1/FOLR1/SLC19A1	2.57657619434143
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	11/233	250/9376	1.77057510729614	EGFR/TFRC/CLTC/FOLR1/PRKCZ/PARD3/ASAP3/FGFR2/DAB2/EHD3/IGF1R	1.97135113104022
Human Diseases	Drug resistance: antineoplastic	hsa01521	EGFR tyrosine kinase inhibitor resistance	5/233	80/9376	2.51502145922747	EGFR/MET/ERBB3/FGFR2/IGF1R	2.17237581502284
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	6/233	110/9376	2.19492781896215	FBN1/BMP7/LTBP1/TFRC/BMPR1A/BMP4	2.01238515741715
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	6/233	112/9376	2.15573267933783	LAMA5/LAMB1/ITGA6/LAMC1/ITGB1/LAMB4	1.96420300204759
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	7/233	142/9376	1.98367889741885	CTSL/HSP90B1/PRKCZ/MGST3/GPC1/BMPR1A/BMP4	1.88547956831311
Organismal Systems	Endocrine system	hsa04928	Parathyroid hormone synthesis, secretion and action	6/233	115/9376	2.09949617465945	EGFR/LRP5/MMP15/GATA3/PRKACB/WNK2	1.89379488673183
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	5/233	88/9376	2.28638314475224	F5/C1QB/A2M/C1QA/CD59	1.93539588130507
Metabolism	Lipid metabolism	hsa00100	Steroid biosynthesis	2/233	20/9376	4.02403433476395	LIPA/DHCR24	2.16110489934783
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	10/233	250/9376	1.60961373390558	LIPA/CTSL/LGMN/ATP6V1B1/CTSV/CLTC/PSAP/AP1B1/TPP1/SLC38A9	1.55956598189276
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	7/233	157/9376	1.79415543588202	PBX1/LIPA/C1QB/LRP1/ITGB5/C1QA/SLC2A1	1.60188992704578
Human Diseases	Infectious disease: bacterial	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	4/233	71/9376	2.26706159705011	EGFR/MET/JAM3/ATP6V1B1	1.71075553063359
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	5/233	100/9376	2.01201716738197	ITGA6/MME/TFRC/CSF3R/CD59	1.62415228917231
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	6/233	130/9376	1.8572466160449	EGFR/COL4A2/GNG12/COL4A1/PRKCZ/PRKACB	1.57115759758356
Organismal Systems	Endocrine system	hsa04614	Renin-angiotensin system	2/233	23/9376	3.49916029109909	ENPEP/MME	1.91558664883786
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	4/233	75/9376	2.14615164520744	LRP2/HSP90B1/GPX8/PRKACB	1.59084230091225
Metabolism	Glycan biosynthesis and metabolism	hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	2/233	24/9376	3.35336194563662	EXTL2/HS6ST2	1.84272843367915
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	4/233	76/9376	2.1179128077705	SLC27A2/SORBS1/DBI/LPL	1.5620412287448
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	4/233	78/9376	2.063607351161	CDH1/MET/ITGB1/CLTC	1.50575078953249
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	7/233	170/9376	1.65695531431457	EGFR/MET/LRP5/MGST3/FZD3/CDK6/IGF1R	1.37988865606614
Organismal Systems	Digestive system	hsa04977	Vitamin digestion and absorption	2/233	26/9376	3.0954110267415	SLC19A3/SLC19A1	1.70792711078023
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	5/233	110/9376	1.82910651580179	EGFR/TFRC/SLC2A1/EPAS1/IGF1R	1.39630329116157
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	3/233	52/9376	2.32155827005612	HSD17B1/PRKACB/IGF1R	1.52547851367234
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	3/233	56/9376	2.15573267933783	TUSC3/MGAT3/GANAB	1.38472231078499
Environmental Information Processing	Signal transduction	hsa04340	Hedgehog signaling pathway	3/233	56/9376	2.15573267933783	LRP2/GLI3/PRKACB	1.38472231078499
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	6/233	148/9376	1.63136527085025	EGFR/LRP5/NOTCH3/FZD3/CDK6/IGF1R	1.23588195965722
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	6/233	150/9376	1.60961373390558	CDH1/EGFR/MET/LRP5/FZD3/FGFR2	1.2014698744761
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	2/233	30/9376	2.6826895565093	FOLR1/SLC19A1	1.4735706986306
NA	NA	hsa04081	Hormone signaling	8/233	219/9376	1.46996688027907	ADRB1/GNG12/SLC40A1/BMPR1A/GHR/PRKACB/SLC16A2/IGF1R	1.12339359226353
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	2/233	31/9376	2.59615118371868	GLDC/ACSS1	1.4209685216246
Cellular Processes	Cellular community - eukaryotes	hsa04540	Gap junction	4/233	89/9376	1.80855475719728	EGFR/ADRB1/GJA1/PRKACB	1.22344924150946
Organismal Systems	Nervous system	hsa04727	GABAergic synapse	4/233	89/9376	1.80855475719728	GABRE/GNG12/SLC38A1/PRKACB	1.22344924150946
Metabolism	Metabolism of other amino acids	hsa00480	Glutathione metabolism	3/233	59/9376	2.0461191532698	GPX8/MGST3/IDH1	1.28673273735036
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	5/233	122/9376	1.64919439949342	NOTCH3/SLC2A1/PRKACB/SLC16A2/BMP4	1.15215038995904
Organismal Systems	Digestive system	hsa04978	Mineral absorption	3/233	61/9376	1.97903327939211	SLC40A1/ATP7B/TRPV6	1.22458851311975
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	3/233	63/9376	1.91620682607807	GLI3/FZD3/BMP4	1.16476479382414
Human Diseases	Drug resistance: antineoplastic	hsa01522	Endocrine resistance	4/233	99/9376	1.62587245849048	EGFR/NOTCH3/PRKACB/IGF1R	0.999352949717505
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	8/233	238/9376	1.35261658311393	EGFR/MET/GNG12/EFNA1/PRKACB/RASA1/FGFR2/IGF1R	0.87959929634143
Human Diseases	Cancer: specific types	hsa05211	Renal cell carcinoma	3/233	70/9376	1.72458614347026	MET/SLC2A1/EPAS1	0.971352269785564
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	6/233	174/9376	1.38759804647033	TUSC3/HSP90B1/SSR1/WFS1/HSPA4L/GANAB	0.823823787819858
Human Diseases	Cancer: specific types	hsa05219	Bladder cancer	2/233	41/9376	1.96294357793363	CDH1/EGFR	0.986404050978858
Human Diseases	Cancer: specific types	hsa05223	Non-small cell lung cancer	3/233	73/9376	1.65371274031395	EGFR/MET/CDK6	0.895068158193278
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	2/233	42/9376	1.91620682607807	TFRC/SLC40A1	0.949956040964665
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	4/233	109/9376	1.4767098476198	PTPRF/SLC27A2/SLC2A1/PRKCZ	0.799129254752057
Human Diseases	Cancer: specific types	hsa05214	Glioma	3/233	76/9376	1.58843460582787	EGFR/CDK6/IGF1R	0.822210022404569
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	3/233	78/9376	1.54770551337075	ITGB1/C1QB/C1QA	0.775387654371773
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	3/233	79/9376	1.52811430434074	SLC6A4/ATP6V1B1/CLTC	0.752470190508367
Organismal Systems	Nervous system	hsa04726	Serotonergic synapse	4/233	115/9376	1.39966411643963	SLC6A4/GNG12/APP/PRKACB	0.688389716642721
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	4/233	116/9376	1.38759804647033	CLDN4/ITGB1/JAM3/CLDN3	0.670539427946444
Organismal Systems	Nervous system	hsa04724	Glutamatergic synapse	4/233	116/9376	1.38759804647033	GNG12/SLC38A1/SHANK2/PRKACB	0.670539427946444
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	9/233	300/9376	1.20721030042918	EGFR/MET/ERBB3/GNG12/EFNA1/PRKACB/RASA1/FGFR2/IGF1R	0.582296209414534
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	5/233	155/9376	1.29807559185934	EGFR/PBX1/FZD3/CDK6/PRKACB	0.597341229976222
Metabolism	Energy metabolism	hsa00910	Nitrogen metabolism	1/233	17/9376	2.36707902044938	CA8	0.900580614791169
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	2/233	50/9376	1.60961373390558	MET/LRP1	0.689939926419682
Environmental Information Processing	Signal transduction	hsa04150	mTOR signaling pathway	5/233	158/9376	1.27342858695062	LRP5/ATP6V1B1/FZD3/IGF1R/SLC38A9	0.553316152620259
Organismal Systems	Endocrine system	hsa04911	Insulin secretion	3/233	86/9376	1.4037329074758	PCLO/SLC2A1/PRKACB	0.600419456156503
Human Diseases	Infectious disease: bacterial	hsa05110	Vibrio cholerae infection	2/233	51/9376	1.57805268029959	ATP6V1B1/PRKACB	0.660765448943565
Metabolism	Metabolism of cofactors and vitamins	hsa00785	Lipoic acid metabolism	1/233	19/9376	2.1179128077705	GLDC	0.778638110358914
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	2/233	53/9376	1.51850352255243	CLTC/PRKACB	0.60427001281779
Human Diseases	Substance dependence	hsa05032	Morphine addiction	3/233	91/9376	1.32660472574636	GABRE/GNG12/PRKACB	0.499771452758714
Organismal Systems	Digestive system	hsa04970	Salivary secretion	3/233	93/9376	1.29807559185934	ADRB1/PRKACB/TRPV6	0.461150785620665
Metabolism	Glycan biosynthesis and metabolism	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	1/233	21/9376	1.91620682607807	CHPF	0.670965999616855
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	9/233	323/9376	1.12124795705497	EGFR/MET/TIMP3/NOTCH3/ERBB3/TP63/FZD3/CDK6/EFNA1	0.353996256648296
Metabolism	Amino acid metabolism	hsa00340	Histidine metabolism	1/233	22/9376	1.82910651580179	AOC1	0.621501562255328
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	2/233	59/9376	1.3640794355132	ADRB1/PRKACB	0.447819856090574
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	2/233	59/9376	1.3640794355132	CDH1/EGFR	0.447819856090574
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	4/233	138/9376	1.1663867636997	PTPRF/SORBS1/PRKCZ/PRKACB	0.314331986853929
Human Diseases	Cancer: overview	hsa05207	Chemical carcinogenesis - receptor activation	6/233	217/9376	1.11263622159372	EGFR/ADRB1/HSP90B1/MGST3/PAQR7/PRKACB	0.267980473276004
Organismal Systems	Aging	hsa04213	Longevity regulating pathway - multiple species	2/233	62/9376	1.29807559185934	PRKACB/IGF1R	0.375900914038367
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	4/233	140/9376	1.14972409564684	CDH1/NOTCH3/GNG12/PRKACB	0.284926598286521
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	3/233	101/9376	1.19525772319721	COL4A2/COL4A1/PRKCZ	0.314942439747418
Organismal Systems	Endocrine system	hsa04927	Cortisol synthesis and secretion	2/233	65/9376	1.2381644106966	PBX1/PRKACB	0.307577539534722
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	2/233	66/9376	1.21940434386786	HSD17B1/STS	0.285536471070767
Metabolism	Lipid metabolism	hsa01040	Biosynthesis of unsaturated fatty acids	1/233	27/9376	1.49038308694961	HACD3	0.4073371535125
Metabolism	Lipid metabolism	hsa00062	Fatty acid elongation	1/233	28/9376	1.43715511955855	HACD3	0.369806441306667
Metabolism	Glycan biosynthesis and metabolism	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	1/233	28/9376	1.43715511955855	B3GNT3	0.369806441306667
Organismal Systems	Excretory system	hsa04966	Collecting duct acid secretion	1/233	28/9376	1.43715511955855	ATP6V1B1	0.369806441306667
Organismal Systems	Endocrine system	hsa04924	Renin secretion	2/233	69/9376	1.1663867636997	ADRB1/PRKACB	0.221440830633117
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	2/233	70/9376	1.14972409564684	DAG1/DMD	0.200714354612993
Metabolism	Carbohydrate metabolism	hsa00020	Citrate cycle (TCA cycle)	1/233	30/9376	1.34134477825465	IDH1	0.298923625823212
Metabolism	Glycan biosynthesis and metabolism	hsa00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	1/233	30/9376	1.34134477825465	PGAP1	0.298923625823212
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	4/233	156/9376	1.0318036755805	EGFR/CLDN4/CDK6/CLDN3	0.0639430565480828
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/233	32/9376	1.25751072961373	ACSS1	0.232928774880186
NA	NA	hsa04082	Neuroactive ligand signaling	5/233	199/9376	1.01106390320702	SLC6A4/ADRB1/GABRE/GNG12/PRKACB	0.0251827862284576
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	3/233	116/9376	1.04069853485275	GLDC/ACSS1/IDH1	0.070407920078378
Human Diseases	Infectious disease: bacterial	hsa05130	Pathogenic Escherichia coli infection	5/233	200/9376	1.00600858369099	CLDN4/ITGB1/MYH10/NCKAP1/CLDN3	0.0137113320659654
Human Diseases	Drug resistance: antineoplastic	hsa01524	Platinum drug resistance	2/233	75/9376	1.07307582260372	MGST3/ATP7B	0.101428210008734
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	5/233	201/9376	1.00100356586168	MET/SPINT1/PBX1/MLLT1/IGF1R	0.0022959377592643
Metabolism	Global and overview maps	hsa01210	2-Oxocarboxylic acid metabolism	1/233	33/9376	1.21940434386786	IDH1	0.201547890062589
Human Diseases	Cancer: specific types	hsa05212	Pancreatic cancer	2/233	77/9376	1.04520372331531	EGFR/CDK6	0.0635800237155476
Genetic Information Processing	Transcription	hsa03020	RNA polymerase	1/233	34/9376	1.18353951022469	POLR2L	0.171146623040925
Metabolism	Carbohydrate metabolism	hsa00500	Starch and sucrose metabolism	1/233	36/9376	1.11778731521221	AGL	0.113030480518917
Metabolism	Glycan biosynthesis and metabolism	hsa00512	Mucin type O-glycan biosynthesis	1/233	36/9376	1.11778731521221	B3GNT3	0.113030480518917
Genetic Information Processing	Replication and repair	hsa03030	DNA replication	1/233	36/9376	1.11778731521221	MCM6	0.113030480518917
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	4/233	168/9376	0.958103413039035	EGFR/CSF3R/LIFR/GHR	-0.0874721637739345
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	1/233	37/9376	1.0875768472335	CDH1	0.0852038501108224
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	6/233	254/9376	0.950559291676523	EGFR/MET/ADRB1/ERBB3/PRKACB/FGFR2	-0.127519249282974
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	2/233	82/9376	0.981471788966817	CTSL/LGMN	-0.0269003740903501
Organismal Systems	Immune system	hsa04611	Platelet activation	3/233	126/9376	0.958103413039035	ITGB1/PRKCZ/PRKACB	-0.0755809402401342
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	2/233	83/9376	0.969646827653964	SLC27A2/IDH1	-0.0443388479065486
Metabolism	Metabolism of cofactors and vitamins	hsa00670	One carbon pool by folate	1/233	39/9376	1.0318036755805	GLDC	0.0317705825102154
Environmental Information Processing	Signal transduction	hsa04012	ErbB signaling pathway	2/233	86/9376	0.935821938317197	EGFR/ERBB3	-0.0954436861084378
Metabolism	Amino acid metabolism	hsa00260	Glycine, serine and threonine metabolism	1/233	41/9376	0.981471788966817	GLDC	-0.0189796192002671
Human Diseases	Substance dependence	hsa05033	Nicotine addiction	1/233	41/9376	0.981471788966817	GABRE	-0.0189796192002671
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/233	42/9376	0.958103413039035	AOC1	-0.0434398814181924
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	5/233	224/9376	0.898221949724096	NRP1/MMP7/SLC2A1/MSX2/PRKACB	-0.246115728644905
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	2/233	90/9376	0.894229852169766	PRKACB/IGF1R	-0.16094936412753
Organismal Systems	Digestive system	hsa04976	Bile secretion	2/233	90/9376	0.894229852169766	SLC2A1/PRKACB	-0.16094936412753
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	1/233	44/9376	0.914553257900897	TUSC3	-0.0906888136450285
Organismal Systems	Excretory system	hsa04962	Vasopressin-regulated water reabsorption	1/233	44/9376	0.914553257900897	PRKACB	-0.0906888136450285
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	3/233	139/9376	0.868496619013802	EGFR/HSP90B1/PRKACB	-0.249343519878113
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	2/233	93/9376	0.865383727906226	NOTCH3/GATA3	-0.208263948235869
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	2/233	93/9376	0.865383727906226	EGFR/PRKACB	-0.208263948235869
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	2/233	95/9376	0.8471651231082	CTSL/ATP6V1B1	-0.239004526771608
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	1/233	47/9376	0.856177518034883	ACSS1	-0.157789245830774
Human Diseases	Endocrine and metabolic disease	hsa04930	Type II diabetes mellitus	1/233	47/9376	0.856177518034883	PRKCZ	-0.157789245830774
Organismal Systems	Environmental adaptation	hsa04713	Circadian entrainment	2/233	97/9376	0.829697800982257	GNG12/PRKACB	-0.269137847313433
Human Diseases	Substance dependence	hsa05030	Cocaine addiction	1/233	49/9376	0.821231496890602	PRKACB	-0.200279866907122
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	2/233	99/9376	0.812936229245242	C1QB/C1QA	-0.29869141636289
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	2/233	99/9376	0.812936229245242	EGFR/SLC44A5	-0.29869141636289
Organismal Systems	Immune system	hsa04062	Chemokine signaling pathway	4/233	193/9376	0.833996753318953	GNG12/PRKCZ/PARD3/PRKACB	-0.37198222104843
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/233	50/9376	0.80480686695279	AOC1	-0.220912896744347
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	2/233	101/9376	0.796838482131475	FZD3/PRKACB	-0.327690925883004
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	1/233	51/9376	0.789026340149794	PLD3	-0.241161592735699
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	2/233	103/9376	0.781365890245427	C1QB/C1QA	-0.356160407668442
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	2/233	104/9376	0.773852756685375	PLD3/CDS1	-0.370203478511263
Organismal Systems	Endocrine system	hsa04922	Glucagon signaling pathway	2/233	107/9376	0.752155950423168	SLC2A1/PRKACB	-0.411597931084873
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	1/233	55/9376	0.731642606320718	PSAP	-0.318627235042906
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	6/233	298/9376	0.8102082553216	BMP7/CSF3R/LIFR/BMPR1A/GHR/BMP4	-0.531507747980308
Cellular Processes	Cell growth and death	hsa04110	Cell cycle	3/233	158/9376	0.76405715217037	CDK6/MCM6/TFDP2	-0.477459179580724
Metabolism	Global and overview maps	hsa01212	Fatty acid metabolism	1/233	57/9376	0.7059709359235	HACD3	-0.355436703441656
Organismal Systems	Endocrine system	hsa04914	Progesterone-mediated oocyte maturation	2/233	110/9376	0.731642606320718	PRKACB/IGF1R	-0.451942307605144
Organismal Systems	Nervous system	hsa04730	Long-term depression	1/233	60/9376	0.670672389127325	IGF1R	-0.408515244468864
Organismal Systems	Nervous system	hsa04725	Cholinergic synapse	2/233	115/9376	0.699832058219817	GNG12/PRKACB	-0.517015453446391
Environmental Information Processing	Signal transduction	hsa04330	Notch signaling pathway	1/233	62/9376	0.649037795929669	NOTCH3	-0.442595827722833
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	3/233	169/9376	0.71432562155573	CTSL/PRKACB/IGF1R	-0.598239122379538
Metabolism	Lipid metabolism	hsa00590	Arachidonic acid metabolism	1/233	63/9376	0.63873560869269	PTGES	-0.459271893943742
Genetic Information Processing	Replication and repair	hsa03420	Nucleotide excision repair	1/233	63/9376	0.63873560869269	POLR2L	-0.459271893943742
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	1/233	65/9376	0.6190822053483	LPL	-0.491936463979986
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	1/233	66/9376	0.609702171933932	GATA3	-0.507940100582911
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	2/233	122/9376	0.659677759797369	GHR/PRKACB	-0.603983031996516
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	1/233	67/9376	0.600602139517007	ACSS1	-0.523734109226352
Organismal Systems	Nervous system	hsa04720	Long-term potentiation	1/233	67/9376	0.600602139517007	PRKACB	-0.523734109226352
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	4/233	227/9376	0.709080940046511	EGFR/GNG12/CDK6/PRKACB	-0.708300468720309
Human Diseases	Substance dependence	hsa05031	Amphetamine addiction	1/233	69/9376	0.583193381849848	PRKACB	-0.554719628438324
Organismal Systems	Endocrine system	hsa04920	Adipocytokine signaling pathway	1/233	70/9376	0.574862047823421	SLC2A1	-0.569923560559579
Human Diseases	Cancer: overview	hsa05204	Chemical carcinogenesis - DNA adducts	1/233	70/9376	0.574862047823421	MGST3	-0.569923560559579
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	1/233	71/9376	0.566765399262528	ELF5	-0.584942745482132
Metabolism	Xenobiotics biodegradation and metabolism	hsa00982	Drug metabolism - cytochrome P450	1/233	73/9376	0.55123758010465	MGST3	-0.614448714047063
Genetic Information Processing	Information processing in viruses	hsa03250	Viral life cycle - HIV-1	1/233	73/9376	0.55123758010465	MLLT1	-0.614448714047063
Environmental Information Processing	Signal transduction	hsa04068	FoxO signaling pathway	2/233	133/9376	0.605117945077285	EGFR/IGF1R	-0.732159970323695
Organismal Systems	Nervous system	hsa04728	Dopaminergic synapse	2/233	133/9376	0.605117945077285	GNG12/PRKACB	-0.732159970323695
Metabolism	Global and overview maps	hsa01230	Biosynthesis of amino acids	1/233	75/9376	0.53653791130186	IDH1	-0.643278835443022
Cellular Processes	Cell growth and death	hsa04115	p53 signaling pathway	1/233	75/9376	0.53653791130186	CDK6	-0.643278835443022
Organismal Systems	Circulatory system	hsa04270	Vascular smooth muscle contraction	2/233	134/9376	0.600602139517007	MYH10/PRKACB	-0.743351787357891
Organismal Systems	Digestive system	hsa04971	Gastric acid secretion	1/233	76/9376	0.529478201942625	PRKACB	-0.657452390275899
Human Diseases	Cancer: specific types	hsa05220	Chronic myeloid leukemia	1/233	77/9376	0.522601861657656	CDK6	-0.671470903974926
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	2/233	137/9376	0.587450267848752	CTSL/CTSV	-0.77650337615823
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	1/233	78/9376	0.51590183779025	ISYNA1	-0.685338615949654
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	1/233	78/9376	0.51590183779025	ITGB1	-0.685338615949654
Cellular Processes	Cell growth and death	hsa04114	Oocyte meiosis	2/233	138/9376	0.583193381849848	PRKACB/IGF1R	-0.787416315479693
Metabolism	Xenobiotics biodegradation and metabolism	hsa00980	Metabolism of xenobiotics by cytochrome P450	1/233	79/9376	0.509371434780247	MGST3	-0.699059591655289
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/233	82/9376	0.490735894483408	MGST3	-0.739380338698044
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	2/233	143/9376	0.562802004862091	C1QB/C1QA	-0.840996138133596
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	1/233	83/9376	0.484823413826982	POLR2L	-0.75255185978355
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	2/233	144/9376	0.558893657606104	C1QB/C1QA	-0.85152203201638
Organismal Systems	Sensory system	hsa04742	Taste transduction	1/233	86/9376	0.467910969158599	PRKACB	-0.791306828373378
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	1/233	87/9376	0.462532682156776	EGFR	-0.803982220311518
Human Diseases	Cancer: overview	hsa05235	PD-L1 expression and PD-1 checkpoint pathway in cancer	1/233	90/9376	0.447114926084883	EGFR	-0.841319624749586
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	2/233	154/9376	0.522601861657656	ADRB1/PRKACB	-0.953559421324485
Organismal Systems	Endocrine system	hsa04921	Oxytocin signaling pathway	2/233	154/9376	0.522601861657656	EGFR/PRKACB	-0.953559421324485
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	1/233	94/9376	0.428088759017441	HSP90B1	-0.88959230240444
Environmental Information Processing	Signal transduction	hsa04070	Phosphatidylinositol signaling system	1/233	98/9376	0.410615748445301	CDS1	-0.936275415283828
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	1/233	98/9376	0.410615748445301	ASAP3	-0.936275415283828
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/233	98/9376	0.410615748445301	PRKACB	-0.936275415283828
Organismal Systems	Sensory system	hsa04750	Inflammatory mediator regulation of TRP channels	1/233	99/9376	0.406468114622621	PRKACB	-0.947713599403087
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	3/233	226/9376	0.534163849747427	ADRB1/GLI3/PRKACB	-1.13160823535146
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	1/233	109/9376	0.369177461904949	GATA3	-1.05747499714072
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	2/233	181/9376	0.444644677874469	PLA2R1/MRC1	-1.20435244227235
Genetic Information Processing	Chromosome	hsa03082	ATP-dependent chromatin remodeling	1/233	117/9376	0.343934558526833	SMARCA1	-1.1399276535843
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	3/233	248/9376	0.486778346947252	HSP90B1/NCKAP1/PFN2	-1.307561831273
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/233	120/9376	0.335336194563662	MAGED1	-1.16976929800748
Human Diseases	Substance dependence	hsa05034	Alcoholism	2/233	191/9376	0.421364851807743	GNG12/PRKACB	-1.28973698113958
Human Diseases	Infectious disease: bacterial	hsa05131	Shigellosis	3/233	253/9376	0.477158221513512	EGFR/ITGB1/PFN2	-1.34580130550298
Environmental Information Processing	Signal transduction	hsa04152	AMPK signaling pathway	1/233	122/9376	0.329838879898684	IGF1R	-1.18936083931503
Cellular Processes	Cell motility	hsa04814	Motor proteins	2/233	194/9376	0.414848900491129	MYH10/MYO7A	-1.3146782710599
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	1/233	125/9376	0.321922746781116	PRKCZ	-1.21831356739961
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	2/233	196/9376	0.410615748445301	GNG12/CDK6	-1.33114222897753
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	2/233	205/9376	0.392588715586727	CDK6/PRKACB	-1.40368829534196
Human Diseases	Infectious disease: viral	hsa05162	Measles	1/233	136/9376	0.295884877556173	CDK6	-1.32037222261324
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	1/233	138/9376	0.291596690924924	ITGB1	-1.3382904666465
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	2/233	214/9376	0.376077975211584	GNG12/AP1B1	-1.47387719282837
Genetic Information Processing	Folding, sorting and degradation	hsa04120	Ubiquitin mediated proteolysis	1/233	142/9376	0.283382699631264	RHOBTB1	-1.37358571144546
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	1/233	142/9376	0.283382699631264	TREM2	-1.37358571144546
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	1/233	149/9376	0.270069418440533	EGFR	-1.43371778360718
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	1/233	157/9376	0.256307919411716	CDK6	-1.50010035679599
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	1/233	163/9376	0.246873272071408	HSPG2	-1.54839074258811
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/233	166/9376	0.242411706913491	ADRB1	-1.57208752951905
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	1/233	173/9376	0.2326031407378	CDK6	-1.62628852180979
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	1/233	205/9376	0.196294357793363	CDK6	-1.85731189362984
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	3/233	370/9376	0.32627305417005	ADRB1/GABRE/GHR	-2.1107560703239
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	1/233	216/9376	0.186297885868701	HSP90B1	-1.93136262094384
Organismal Systems	Sensory system	hsa04740	Olfactory transduction	1/233	449/9376	0.0896221455403997	PRKACB	-3.15581347784998