ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0005201 extracellular matrix structural constituent 19/376 168/18639 0.113095238095238 5.60633548632219 1.38266798051579e-09 5.14095511402006e-07 GO:0008201 heparin binding 19/376 172/18639 0.11046511627907 5.47595559129144 2.06088356547372e-09 5.14095511402006e-07 GO:0019838 growth factor binding 17/376 136/18639 0.125 6.19647606382979 2.19698936496584e-09 5.14095511402006e-07 GO:0005539 glycosaminoglycan binding 22/376 242/18639 0.0909090909090909 4.50652804642166 4.44494361013392e-09 7.80087603578503e-07 GO:0050840 extracellular matrix binding 12/376 67/18639 0.17910447761194 8.87853286757701 8.42547920048627e-09 1.18293727974827e-06 GO:0003735 structural constituent of ribosome 18/376 175/18639 0.102857142857143 5.09881458966565 1.70760528457319e-08 1.99789818295063e-06 GO:0005178 integrin binding 17/376 161/18639 0.105590062111801 5.23429033963262 2.89417391690874e-08 2.90244298524277e-06 GO:0098631 cell adhesion mediator activity 12/376 76/18639 0.157894736842105 7.82712765957447 3.70231419020388e-08 3.2487807019039e-06 GO:1901681 sulfur compound binding 22/376 275/18639 0.08 3.96574468085106 4.55352862084778e-08 3.55175232426126e-06 GO:0019199 transmembrane receptor protein kinase activity 11/376 78/18639 0.141025641025641 6.99089607201309 4.51445707195387e-07 3.16914886451162e-05 GO:0038024 cargo receptor activity 10/376 65/18639 0.153846153846154 7.62643207855974 6.60660867484975e-07 4.21621753613139e-05 GO:0043236 laminin binding 7/376 29/18639 0.241379310344828 11.9656089508437 1.36833161331938e-06 8.00473993791836e-05 GO:0070325 lipoprotein particle receptor binding 7/376 31/18639 0.225806451612903 11.1936341798216 2.22656297675147e-06 0.000120234400744579 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 5/376 13/18639 0.384615384615385 19.0660801963993 3.66439897847417e-06 0.000183743434492062 GO:0001618 virus receptor activity 10/376 81/18639 0.123456790123457 6.11997635933806 5.20673739899097e-06 0.000243675310272777 GO:0140272 exogenous protein binding 10/376 82/18639 0.121951219512195 6.04534250129735 5.82487198852221e-06 0.000255566258496412 GO:0030215 semaphorin receptor binding 6/376 24/18639 0.25 12.3929521276596 6.40813470621076e-06 0.000264618268456468 GO:0043394 proteoglycan binding 7/376 37/18639 0.189189189189189 9.37845025876941 7.85492204961102e-06 0.00030634195993483 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 9/376 68/18639 0.132352941176471 6.56097465581977 8.67098937701298e-06 0.000320370239087532 GO:0050750 low-density lipoprotein particle receptor binding 6/376 26/18639 0.230769230769231 11.4396481178396 1.05935307018638e-05 0.000371832927635421 GO:0005518 collagen binding 9/376 72/18639 0.125 6.19647606382979 1.39509319839328e-05 0.00046635972632004 GO:0009055 electron transfer activity 11/376 116/18639 0.0948275862068965 4.70077494497432 2.30395092419456e-05 0.000735169794902083 GO:0004714 transmembrane receptor protein tyrosine kinase activity 8/376 60/18639 0.133333333333333 6.60957446808511 2.60688944853516e-05 0.000791404723402073 GO:0022853 active monoatomic ion transmembrane transporter activity 11/376 118/18639 0.0932203389830508 4.62110079336459 2.70565717402418e-05 0.000791404723402073 GO:0033218 amide binding 16/376 247/18639 0.0647773279352227 3.21112929623568 4.45518628616271e-05 0.00125101630915449 GO:0008013 beta-catenin binding 10/376 106/18639 0.0943396226415094 4.67658570855078 5.65264379031982e-05 0.00152621382338635 GO:0022804 active transmembrane transporter activity 23/376 457/18639 0.050328227571116 2.49486125983519 5.9424871000021e-05 0.00154504664600055 GO:0017154 semaphorin receptor activity 4/376 13/18639 0.307692307692308 15.2528641571195 0.000100876956572135 0.00244191805219445 GO:0031994 insulin-like growth factor I binding 4/376 13/18639 0.307692307692308 15.2528641571195 0.000100876956572135 0.00244191805219445 GO:0098632 cell-cell adhesion mediator activity 7/376 55/18639 0.127272727272727 6.30913926499033 0.00011337374000829 0.00265294551619399 GO:0008137 NADH dehydrogenase (ubiquinone) activity 6/376 41/18639 0.146341463414634 7.25441100155682 0.000160294024944402 0.00362988404874098 GO:0005044 scavenger receptor activity 5/376 27/18639 0.185185185185185 9.17996453900709 0.00018213869777486 0.00399566768243599 GO:0045499 chemorepellent activity 5/376 28/18639 0.178571428571429 8.85210866261398 0.000218091963841331 0.00463941086717013 GO:0003954 NADH dehydrogenase activity 6/376 44/18639 0.136363636363636 6.75979206963249 0.000239169902183486 0.00479706489522306 GO:0030020 extracellular matrix structural constituent conferring tensile strength 6/376 44/18639 0.136363636363636 6.75979206963249 0.000239169902183486 0.00479706489522306 GO:0005507 copper ion binding 7/376 63/18639 0.111111111111111 5.50797872340426 0.00026926730570618 0.00525071246127052 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 4/376 17/18639 0.235294117647059 11.6639549436796 0.00031498283062384 0.00581889334468252 GO:0019198 transmembrane receptor protein phosphatase activity 4/376 17/18639 0.235294117647059 11.6639549436796 0.00031498283062384 0.00581889334468252 GO:0016500 protein-hormone receptor activity 7/376 67/18639 0.104477611940299 5.17914417275325 0.000395074999294947 0.00699091433411033 GO:0034185 apolipoprotein binding 4/376 18/18639 0.222222222222222 11.0159574468085 0.000398564824190713 0.00699091433411033 GO:0071813 lipoprotein particle binding 5/376 32/18639 0.15625 7.74559507978723 0.000418259831955319 0.00699091433411033 GO:0071814 protein-lipid complex binding 5/376 32/18639 0.15625 7.74559507978723 0.000418259831955319 0.00699091433411033 GO:0005006 epidermal growth factor receptor activity 6/376 50/18639 0.12 5.9486170212766 0.000486396262733757 0.00775100836962832 GO:0005520 insulin-like growth factor binding 4/376 19/18639 0.210526315789474 10.436170212766 0.00049685951087361 0.00775100836962832 GO:0043395 heparan sulfate proteoglycan binding 4/376 19/18639 0.210526315789474 10.436170212766 0.00049685951087361 0.00775100836962832 GO:0005010 insulin-like growth factor receptor activity 6/376 51/18639 0.117647058823529 5.8319774718398 0.000542007671316776 0.00809551883541227 GO:0005021 vascular endothelial growth factor receptor activity 6/376 51/18639 0.117647058823529 5.8319774718398 0.000542007671316776 0.00809551883541227 GO:0015399 primary active transmembrane transporter activity 11/376 166/18639 0.0662650602409639 3.28487887721097 0.000564642660197057 0.00825789890538197 GO:0019955 cytokine binding 10/376 144/18639 0.0694444444444444 3.44248670212766 0.000693716516082795 0.00993855090388005 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 6/376 58/18639 0.103448275862069 5.12811812179017 0.00108237366865496 0.0151965263079156 GO:0008514 organic anion transmembrane transporter activity 14/376 269/18639 0.0520446096654275 2.57994542434549 0.0011884744970747 0.0160820835480778 GO:0097493 structural molecule activity conferring elasticity 3/376 11/18639 0.272727272727273 13.519584139265 0.00119126544800576 0.0160820835480778 GO:0030165 PDZ domain binding 7/376 83/18639 0.0843373493975904 4.18075493463215 0.00143320191000869 0.0189831649212472 GO:0045295 gamma-catenin binding 3/376 12/18639 0.25 12.3929521276596 0.00156469879721119 0.0203410843637455 GO:0003779 actin binding 19/376 443/18639 0.0428893905191874 2.12610465395514 0.00175078541790112 0.0223463884248471 GO:0030276 clathrin binding 5/376 46/18639 0.108695652173913 5.38824005550416 0.00226085795835798 0.028341469406559 GO:0097110 scaffold protein binding 6/376 70/18639 0.0857142857142857 4.24901215805471 0.00286548345079696 0.0309104123603422 GO:0001968 fibronectin binding 4/376 30/18639 0.133333333333333 6.60957446808511 0.00294977689136188 0.0309104123603422 GO:0005004 GPI-linked ephrin receptor activity 5/376 49/18639 0.102040816326531 5.05834780720799 0.00299417099786791 0.0309104123603422 GO:0005008 hepatocyte growth factor receptor activity 5/376 49/18639 0.102040816326531 5.05834780720799 0.00299417099786791 0.0309104123603422 GO:0005009 insulin receptor activity 5/376 49/18639 0.102040816326531 5.05834780720799 0.00299417099786791 0.0309104123603422 GO:0005011 macrophage colony-stimulating factor receptor activity 5/376 49/18639 0.102040816326531 5.05834780720799 0.00299417099786791 0.0309104123603422 GO:0005018 platelet-derived growth factor alpha-receptor activity 5/376 49/18639 0.102040816326531 5.05834780720799 0.00299417099786791 0.0309104123603422 GO:0005020 stem cell factor receptor activity 5/376 49/18639 0.102040816326531 5.05834780720799 0.00299417099786791 0.0309104123603422 GO:0008288 boss receptor activity 5/376 49/18639 0.102040816326531 5.05834780720799 0.00299417099786791 0.0309104123603422 GO:0036332 placental growth factor receptor activity 5/376 49/18639 0.102040816326531 5.05834780720799 0.00299417099786791 0.0309104123603422 GO:0038062 protein tyrosine kinase collagen receptor activity 5/376 49/18639 0.102040816326531 5.05834780720799 0.00299417099786791 0.0309104123603422 GO:0060175 brain-derived neurotrophic factor receptor activity 5/376 49/18639 0.102040816326531 5.05834780720799 0.00299417099786791 0.0309104123603422 GO:0005007 fibroblast growth factor receptor activity 5/376 50/18639 0.1 4.95718085106383 0.00327281263510504 0.0323593587301934 GO:0005017 platelet-derived growth factor receptor activity 5/376 50/18639 0.1 4.95718085106383 0.00327281263510504 0.0323593587301934 GO:0005019 platelet-derived growth factor beta-receptor activity 5/376 50/18639 0.1 4.95718085106383 0.00327281263510504 0.0323593587301934 GO:0072349 modified amino acid transmembrane transporter activity 4/376 31/18639 0.129032258064516 6.39636238846946 0.00333362700211258 0.0325028632705977 GO:0005030 neurotrophin receptor activity 5/376 51/18639 0.0980392156862745 4.85998122653317 0.00356963926160376 0.0343272159129567 GO:0005024 transforming growth factor beta receptor activity 3/376 16/18639 0.1875 9.29471409574468 0.00375142729976629 0.0355878643842694 GO:0005003 ephrin receptor activity 5/376 53/18639 0.0943396226415094 4.67658570855078 0.00422043830158138 0.0384772426975342 GO:0005005 transmembrane-ephrin receptor activity 5/376 53/18639 0.0943396226415094 4.67658570855078 0.00422043830158138 0.0384772426975342 GO:0038064 collagen receptor activity 5/376 53/18639 0.0943396226415094 4.67658570855078 0.00422043830158138 0.0384772426975342 GO:0015078 proton transmembrane transporter activity 10/376 185/18639 0.0540540540540541 2.67955721679126 0.00443290157237922 0.0398790050218056 GO:0030169 low-density lipoprotein particle binding 3/376 17/18639 0.176470588235294 8.7479662077597 0.00448780825743967 0.0398790050218056 GO:0008238 exopeptidase activity 7/376 102/18639 0.0686274509803922 3.40198685857322 0.00460896600380533 0.0404436766833918 GO:0090482 vitamin transmembrane transporter activity 4/376 34/18639 0.117647058823529 5.8319774718398 0.00468599550168644 0.0406119610146158 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 3/376 18/18639 0.166666666666667 8.26196808510638 0.00530565694408945 0.0454215996920829 GO:1990380 K48-linked deubiquitinase activity 3/376 19/18639 0.157894736842105 7.82712765957447 0.00620730646281743 0.0525003510469619 GO:0061134 peptidase regulator activity 11/376 226/18639 0.0486725663716814 2.41278713989832 0.00635884786208437 0.0531417999902765 GO:0001540 amyloid-beta binding 6/376 83/18639 0.072289156626506 3.5835042296847 0.00663651231115199 0.0548097840285729 GO:0042887 amide transmembrane transporter activity 4/376 38/18639 0.105263157894737 5.21808510638298 0.00700296607526726 0.0571637463353212 GO:0004713 protein tyrosine kinase activity 8/376 140/18639 0.0571428571428571 2.83267477203647 0.00758239339975117 0.0611820708807508 GO:0016651 oxidoreductase activity, acting on NAD(P)H 6/376 88/18639 0.0681818181818182 3.37989603481625 0.00876674579914507 0.0692711327937916 GO:1901682 sulfur compound transmembrane transporter activity 5/376 63/18639 0.0793650793650794 3.93427051671733 0.00878223763340093 0.0692711327937916 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 6/376 89/18639 0.0674157303370786 3.34191967487449 0.00924532158513889 0.0713210522282143 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 6/376 89/18639 0.0674157303370786 3.34191967487449 0.00924532158513889 0.0713210522282143 GO:0140793 histone H2AXY142 phosphatase activity 6/376 90/18639 0.0666666666666667 3.30478723404255 0.00974227011116491 0.0743377567178018 GO:0004602 glutathione peroxidase activity 3/376 23/18639 0.130434782608696 6.46588806660499 0.0106902494213858 0.0789953167769773 GO:0005158 insulin receptor binding 3/376 23/18639 0.130434782608696 6.46588806660499 0.0106902494213858 0.0789953167769773 GO:0017134 fibroblast growth factor binding 3/376 23/18639 0.130434782608696 6.46588806660499 0.0106902494213858 0.0789953167769773 GO:0042562 hormone binding 6/376 94/18639 0.0638297872340425 3.16415799004074 0.0119210107702756 0.0871723912576401 GO:0004867 serine-type endopeptidase inhibitor activity 6/376 95/18639 0.0631578947368421 3.13085106382979 0.0125152034617034 0.0893971899390071 GO:0008237 metallopeptidase activity 9/376 184/18639 0.0489130434782609 2.42470802497687 0.0125815452966906 0.0893971899390071 GO:0042277 peptide binding 11/376 249/18639 0.0441767068273092 2.18991925147398 0.0126072960170395 0.0893971899390071 GO:0015291 secondary active transmembrane transporter activity 12/376 287/18639 0.0418118466898955 2.07268885758766 0.0140554879010359 0.098669525065272 GO:0046943 carboxylic acid transmembrane transporter activity 9/376 188/18639 0.0478723404255319 2.37311849253056 0.0143099119521237 0.0992580446314613 GO:0004725 protein tyrosine phosphatase activity 6/376 98/18639 0.0612244897959184 3.03500868432479 0.0144221090490157 0.0992580446314613 GO:0005342 organic acid transmembrane transporter activity 9/376 189/18639 0.0476190476190476 2.36056231003039 0.0147681400531879 0.100652760362504 GO:0008239 dipeptidyl-peptidase activity 2/376 10/18639 0.2 9.91436170212766 0.0164092644419262 0.110762534983002 GO:0035255 ionotropic glutamate receptor binding 3/376 27/18639 0.111111111111111 5.50797872340426 0.016641611064689 0.111261056832492 GO:0004175 endopeptidase activity 15/376 405/18639 0.037037037037037 1.83599290780142 0.0180346829856562 0.119437240150289 GO:0002162 dystroglycan binding 2/376 11/18639 0.181818181818182 9.01305609284333 0.0197910419961308 0.125164968299854 GO:0008271 secondary active sulfate transmembrane transporter activity 2/376 11/18639 0.181818181818182 9.01305609284333 0.0197910419961308 0.125164968299854 GO:0032794 GTPase activating protein binding 2/376 11/18639 0.181818181818182 9.01305609284333 0.0197910419961308 0.125164968299854 GO:0048407 platelet-derived growth factor binding 2/376 11/18639 0.181818181818182 9.01305609284333 0.0197910419961308 0.125164968299854 GO:0050998 nitric-oxide synthase binding 2/376 11/18639 0.181818181818182 9.01305609284333 0.0197910419961308 0.125164968299854 GO:0003785 actin monomer binding 3/376 29/18639 0.103448275862069 5.12811812179017 0.020185058499576 0.125397443068163 GO:0051861 glycolipid binding 3/376 29/18639 0.103448275862069 5.12811812179017 0.020185058499576 0.125397443068163 GO:0140789 histone phosphatase activity 7/376 136/18639 0.0514705882352941 2.55149014392991 0.0204966933294934 0.125936028222715 GO:0030159 signaling receptor complex adaptor activity 4/376 52/18639 0.0769230769230769 3.81321603927987 0.0206305459339206 0.125936028222715 GO:0030414 peptidase inhibitor activity 8/376 169/18639 0.0473372781065089 2.34659448571069 0.0215718883333994 0.130415222663327 GO:0046332 SMAD binding 5/376 79/18639 0.0632911392405063 3.13745623485053 0.0217358704438879 0.130415222663327 GO:0017046 peptide hormone binding 4/376 53/18639 0.0754716981132075 3.74126856684063 0.0219701465569687 0.130703753245695 GO:0015132 prostaglandin transmembrane transporter activity 2/376 12/18639 0.166666666666667 8.26196808510638 0.0234363106359147 0.135969339391835 GO:0017166 vinculin binding 2/376 12/18639 0.166666666666667 8.26196808510638 0.0234363106359147 0.135969339391835 GO:0097371 MDM2/MDM4 family protein binding 2/376 12/18639 0.166666666666667 8.26196808510638 0.0234363106359147 0.135969339391835 GO:0004222 metalloendopeptidase activity 6/376 110/18639 0.0545454545454545 2.703916827853 0.0240671587985611 0.136498138113475 GO:0005310 dicarboxylic acid transmembrane transporter activity 3/376 31/18639 0.0967741935483871 4.79727179135209 0.0241107822308703 0.136498138113475 GO:0017147 Wnt-protein binding 3/376 31/18639 0.0967741935483871 4.79727179135209 0.0241107822308703 0.136498138113475 GO:0004721 phosphoprotein phosphatase activity 8/376 175/18639 0.0457142857142857 2.26613981762918 0.025901667420463 0.145362515146553 GO:0170055 lipid transmembrane transporter activity 4/376 56/18639 0.0714285714285714 3.54084346504559 0.0263022744712758 0.145362515146553 GO:0005542 folic acid binding 2/376 13/18639 0.153846153846154 7.62643207855974 0.0273331225061895 0.145362515146553 GO:0035673 oligopeptide transmembrane transporter activity 2/376 13/18639 0.153846153846154 7.62643207855974 0.0273331225061895 0.145362515146553 GO:0043560 insulin receptor substrate binding 2/376 13/18639 0.153846153846154 7.62643207855974 0.0273331225061895 0.145362515146553 GO:0070123 transforming growth factor beta receptor activity, type III 2/376 13/18639 0.153846153846154 7.62643207855974 0.0273331225061895 0.145362515146553 GO:0070700 BMP receptor binding 2/376 13/18639 0.153846153846154 7.62643207855974 0.0273331225061895 0.145362515146553 GO:0071714 icosanoid transmembrane transporter activity 2/376 13/18639 0.153846153846154 7.62643207855974 0.0273331225061895 0.145362515146553 GO:0016209 antioxidant activity 5/376 86/18639 0.0581395348837209 2.88208189015339 0.0300135415969134 0.158417339857393 GO:0004879 nuclear receptor activity 4/376 59/18639 0.0677966101694915 3.36080057699243 0.0311117004172166 0.162440231175778 GO:0015926 glucosidase activity 2/376 14/18639 0.142857142857143 7.08168693009119 0.0314699023360481 0.162440231175778 GO:0042813 Wnt receptor activity 2/376 14/18639 0.142857142857143 7.08168693009119 0.0314699023360481 0.162440231175778 GO:0004197 cysteine-type endopeptidase activity 5/376 88/18639 0.0568181818181818 2.81658002901354 0.0326968250605237 0.166964893512031 GO:0098531 ligand-modulated transcription factor activity 4/376 60/18639 0.0666666666666667 3.30478723404255 0.032822158553647 0.166964893512031 GO:0061135 endopeptidase regulator activity 8/376 184/18639 0.0434782608695652 2.15529602220166 0.0334784230664148 0.16907807908362 GO:0015026 coreceptor activity 4/376 61/18639 0.0655737704918033 3.25061039414022 0.034586590455539 0.17342704642706 GO:0004129 cytochrome-c oxidase activity 2/376 15/18639 0.133333333333333 6.60957446808511 0.0358354373342782 0.174697757004606 GO:0005041 low-density lipoprotein particle receptor activity 2/376 15/18639 0.133333333333333 6.60957446808511 0.0358354373342782 0.174697757004606 GO:0015116 sulfate transmembrane transporter activity 2/376 15/18639 0.133333333333333 6.60957446808511 0.0358354373342782 0.174697757004606 GO:0061578 K63-linked deubiquitinase activity 2/376 15/18639 0.133333333333333 6.60957446808511 0.0358354373342782 0.174697757004606 GO:0031406 carboxylic acid binding 8/376 187/18639 0.0427807486631016 2.12071908066902 0.0363071657202272 0.175776760935169 GO:0072341 modified amino acid binding 5/376 91/18639 0.0549450549450549 2.72372574234276 0.0369941506672027 0.177875984714906 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 16/376 484/18639 0.0330578512396694 1.63873747142606 0.0373320225838712 0.178279454788283 GO:0043177 organic acid binding 8/376 189/18639 0.0423280423280423 2.09827760891591 0.038280033880384 0.181571512054254 GO:0045296 cadherin binding 12/376 334/18639 0.0359281437125748 1.78102306026245 0.0392604892786041 0.184972238077718 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/376 16/18639 0.125 6.19647606382979 0.0404188673392085 0.187907581934598 GO:0016675 oxidoreductase activity, acting on a heme group of donors 2/376 16/18639 0.125 6.19647606382979 0.0404188673392085 0.187907581934598 GO:0005109 frizzled binding 3/376 38/18639 0.0789473684210526 3.91356382978723 0.0408425818619413 0.188628239915018 GO:0001216 DNA-binding transcription activator activity 16/376 491/18639 0.0325865580448065 1.61537461541795 0.0416186856867903 0.19095632256292 GO:0008236 serine-type peptidase activity 8/376 194/18639 0.0412371134020619 2.04419828909849 0.043523076692664 0.198397401547079 GO:0008235 metalloexopeptidase activity 4/376 66/18639 0.0606060606060606 3.00435203094778 0.044221685743008 0.200281441236075 GO:0004866 endopeptidase inhibitor activity 7/376 161/18639 0.0434782608695652 2.15529602220166 0.0450724906346206 0.200868303811253 GO:0015347 sodium-independent organic anion transmembrane transporter activity 2/376 17/18639 0.117647058823529 5.8319774718398 0.0452096752167777 0.200868303811253 GO:0048038 quinone binding 2/376 17/18639 0.117647058823529 5.8319774718398 0.0452096752167777 0.200868303811253 GO:0004177 aminopeptidase activity 3/376 40/18639 0.075 3.71788563829787 0.0464603835379978 0.205126976375311 GO:0017171 serine hydrolase activity 8/376 198/18639 0.0404040404040404 2.00290135396518 0.0480435736411194 0.210791179350412 GO:0017080 sodium channel regulator activity 3/376 41/18639 0.0731707317073171 3.62720550077841 0.0494047387516173 0.215059356540052 GO:0030228 lipoprotein particle receptor activity 2/376 18/18639 0.111111111111111 5.50797872340426 0.0501976775008637 0.215059356540052 GO:0070064 proline-rich region binding 2/376 18/18639 0.111111111111111 5.50797872340426 0.0501976775008637 0.215059356540052 GO:0015103 inorganic anion transmembrane transporter activity 7/376 165/18639 0.0424242424242424 2.10304642166344 0.0502417869979609 0.215059356540052 GO:0042056 chemoattractant activity 3/376 42/18639 0.0714285714285714 3.54084346504559 0.0524380064926989 0.223099882168937 GO:0008381 mechanosensitive monoatomic ion channel activity 2/376 19/18639 0.105263157894737 5.21808510638298 0.0553730152700456 0.230783777150528 GO:0015245 fatty acid transmembrane transporter activity 2/376 19/18639 0.105263157894737 5.21808510638298 0.0553730152700456 0.230783777150528 GO:0030506 ankyrin binding 2/376 19/18639 0.105263157894737 5.21808510638298 0.0553730152700456 0.230783777150528 GO:0008375 acetylglucosaminyltransferase activity 3/376 43/18639 0.0697674418604651 3.45849826818407 0.0555590574621641 0.230783777150528 GO:0002020 protease binding 6/376 136/18639 0.0441176470588235 2.18699155193993 0.0576936687554304 0.238240914507719 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 2/376 20/18639 0.1 4.95718085106383 0.0607261452551076 0.249296806836757 GO:0046915 transition metal ion transmembrane transporter activity 3/376 45/18639 0.0666666666666667 3.30478723404255 0.0620596783932447 0.253290082744522 GO:0036122 BMP binding 2/376 21/18639 0.0952380952380952 4.72112462006079 0.0662478311717267 0.268820679089897 GO:0005243 gap junction channel activity 2/376 22/18639 0.0909090909090909 4.50652804642166 0.0719291352729159 0.286899164554471 GO:0008093 cytoskeletal anchor activity 2/376 22/18639 0.0909090909090909 4.50652804642166 0.0719291352729159 0.286899164554471 GO:0030021 extracellular matrix structural constituent conferring compression resistance 2/376 22/18639 0.0909090909090909 4.50652804642166 0.0719291352729159 0.286899164554471 GO:0015370 solute:sodium symporter activity 4/376 79/18639 0.0506329113924051 2.50996498788042 0.0755562772147142 0.299663879122765 GO:0035254 glutamate receptor binding 3/376 49/18639 0.0612244897959184 3.03500868432479 0.0760581045751273 0.299959491077188 GO:0043274 phospholipase binding 2/376 23/18639 0.0869565217391304 4.31059204440333 0.0777614101159187 0.303269499452083 GO:0140103 catalytic activity, acting on a glycoprotein 2/376 23/18639 0.0869565217391304 4.31059204440333 0.0777614101159187 0.303269499452083 GO:0019209 kinase activator activity 6/376 148/18639 0.0405405405405405 2.00966791259344 0.0796146850492455 0.308781817152322 GO:0015101 organic cation transmembrane transporter activity 4/376 81/18639 0.0493827160493827 2.44799054373522 0.0811583759566229 0.311020507713978 GO:0008509 monoatomic anion transmembrane transporter activity 6/376 149/18639 0.0402684563758389 1.99618020848208 0.0816264036294893 0.311020507713978 GO:0035401 histone H3Y41 kinase activity 5/376 115/18639 0.0434782608695652 2.15529602220166 0.0834338755705101 0.311020507713978 GO:0140801 histone H2AXY142 kinase activity 5/376 115/18639 0.0434782608695652 2.15529602220166 0.0834338755705101 0.311020507713978 GO:0015149 hexose transmembrane transporter activity 2/376 24/18639 0.0833333333333333 4.13098404255319 0.0837362905383788 0.311020507713978 GO:0050431 transforming growth factor beta binding 2/376 24/18639 0.0833333333333333 4.13098404255319 0.0837362905383788 0.311020507713978 GO:0055056 D-glucose transmembrane transporter activity 2/376 24/18639 0.0833333333333333 4.13098404255319 0.0837362905383788 0.311020507713978 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 2/376 24/18639 0.0833333333333333 4.13098404255319 0.0837362905383788 0.311020507713978 GO:0008234 cysteine-type peptidase activity 7/376 187/18639 0.0374331550802139 1.85562919558539 0.0851952508185766 0.314774031971794 GO:0015294 solute:monoatomic cation symporter activity 5/376 116/18639 0.0431034482758621 2.13671588407924 0.0858314794906628 0.315464390588719 GO:0005080 protein kinase C binding 3/376 52/18639 0.0576923076923077 2.8599120294599 0.0873843174636656 0.319498910726527 GO:1990782 protein tyrosine kinase binding 5/376 117/18639 0.0427350427350427 2.11845335515548 0.0882649750760736 0.320476373780153 GO:0003707 nuclear steroid receptor activity 2/376 25/18639 0.08 3.96574468085106 0.0898456858387238 0.320476373780153 GO:0015645 fatty acid ligase activity 2/376 25/18639 0.08 3.96574468085106 0.0898456858387238 0.320476373780153 GO:0120515 fatty acid-CoA ligase activity 2/376 25/18639 0.08 3.96574468085106 0.0898456858387238 0.320476373780153 GO:0051117 ATPase binding 4/376 84/18639 0.0476190476190476 2.36056231003039 0.0899342530408691 0.320476373780153 GO:0015145 monosaccharide transmembrane transporter activity 2/376 26/18639 0.0769230769230769 3.81321603927987 0.0960817721558268 0.335569174394977 GO:0030507 spectrin binding 2/376 26/18639 0.0769230769230769 3.81321603927987 0.0960817721558268 0.335569174394977 GO:0043548 phosphatidylinositol 3-kinase binding 2/376 26/18639 0.0769230769230769 3.81321603927987 0.0960817721558268 0.335569174394977 GO:0070006 metalloaminopeptidase activity 2/376 26/18639 0.0769230769230769 3.81321603927987 0.0960817721558268 0.335569174394977 GO:0015108 chloride transmembrane transporter activity 5/376 121/18639 0.0413223140495868 2.04842183928257 0.0983533120570917 0.341802104277616 GO:0004364 glutathione transferase activity 2/376 27/18639 0.0740740740740741 3.67198581560284 0.102436985043118 0.352503742648376 GO:0016405 CoA-ligase activity 2/376 27/18639 0.0740740740740741 3.67198581560284 0.102436985043118 0.352503742648376 GO:0004601 peroxidase activity 3/376 57/18639 0.0526315789473684 2.60904255319149 0.107712709434443 0.365792423862057 GO:0016504 peptidase activator activity 3/376 57/18639 0.0526315789473684 2.60904255319149 0.107712709434443 0.365792423862057 GO:0046875 ephrin receptor binding 2/376 28/18639 0.0714285714285714 3.54084346504559 0.108904012232436 0.365792423862057 GO:0051119 sugar transmembrane transporter activity 2/376 28/18639 0.0714285714285714 3.54084346504559 0.108904012232436 0.365792423862057 GO:0097718 disordered domain specific binding 2/376 28/18639 0.0714285714285714 3.54084346504559 0.108904012232436 0.365792423862057 GO:0001217 DNA-binding transcription repressor activity 9/376 278/18639 0.0323741007194245 1.60484272156743 0.111252418435456 0.371900941627097 GO:0004181 metallocarboxypeptidase activity 2/376 29/18639 0.0689655172413793 3.41874541452678 0.115475786583018 0.384189583797529 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 3/376 59/18639 0.0508474576271186 2.52060043274432 0.116313609733243 0.385151669965738 GO:0033612 receptor serine/threonine kinase binding 2/376 30/18639 0.0666666666666667 3.30478723404255 0.122145479211135 0.40068283367391 GO:0098918 structural constituent of synapse 2/376 30/18639 0.0666666666666667 3.30478723404255 0.122145479211135 0.40068283367391 GO:0005516 calmodulin binding 7/376 207/18639 0.0338164251207729 1.67634135060129 0.12650249385987 0.413045352044786 GO:0005452 solute:inorganic anion antiporter activity 2/376 31/18639 0.0645161290322581 3.19818119423473 0.128906492795981 0.417015474390685 GO:0016878 acid-thiol ligase activity 2/376 31/18639 0.0645161290322581 3.19818119423473 0.128906492795981 0.417015474390685 GO:0015106 bicarbonate transmembrane transporter activity 2/376 32/18639 0.0625 3.09823803191489 0.135752455057532 0.435151705252912 GO:0042910 xenobiotic transmembrane transporter activity 2/376 32/18639 0.0625 3.09823803191489 0.135752455057532 0.435151705252912 GO:0004857 enzyme inhibitor activity 12/376 416/18639 0.0288461538461538 1.42995601472995 0.137607787029767 0.438039441806274 GO:0015297 antiporter activity 5/376 135/18639 0.037037037037037 1.83599290780142 0.137901305753827 0.438039441806274 GO:0019956 chemokine binding 2/376 33/18639 0.0606060606060606 3.00435203094778 0.142677212402194 0.449145305409597 GO:0030296 protein tyrosine kinase activator activity 2/376 33/18639 0.0606060606060606 3.00435203094778 0.142677212402194 0.449145305409597 GO:0019843 rRNA binding 3/376 65/18639 0.0461538461538462 2.28792962356792 0.143548627922581 0.449871146435945 GO:0004252 serine-type endopeptidase activity 6/376 176/18639 0.0340909090909091 1.68994801740812 0.146170344057 0.456051473457841 GO:0008376 acetylgalactosaminyltransferase activity 2/376 34/18639 0.0588235294117647 2.9159887359199 0.149674823732141 0.464873240805447 GO:0030295 protein kinase activator activity 5/376 139/18639 0.0359712230215827 1.78315857951936 0.150322258778969 0.464873240805447 GO:0005154 epidermal growth factor receptor binding 2/376 35/18639 0.0571428571428571 2.83267477203647 0.156739554414367 0.480485446283344 GO:0005343 organic acid:sodium symporter activity 2/376 35/18639 0.0571428571428571 2.83267477203647 0.156739554414367 0.480485446283344 GO:0004674 protein serine/threonine kinase activity 12/376 433/18639 0.0277136258660508 1.37381455456734 0.167475118676915 0.496513097551657 GO:0008028 monocarboxylic acid transmembrane transporter activity 3/376 70/18639 0.0428571428571429 2.12450607902736 0.167679112887165 0.496513097551657 GO:0022829 wide pore channel activity 2/376 37/18639 0.0540540540540541 2.67955721679126 0.171048432528877 0.496513097551657 GO:0030280 structural constituent of skin epidermis 2/376 37/18639 0.0540540540540541 2.67955721679126 0.171048432528877 0.496513097551657 GO:0015293 symporter activity 5/376 146/18639 0.0342465753424658 1.69766467502186 0.173130670159677 0.496513097551657 GO:0004843 cysteine-type deubiquitinase activity 4/376 108/18639 0.037037037037037 1.83599290780142 0.174338700296749 0.496513097551657 GO:0005496 steroid binding 4/376 108/18639 0.037037037037037 1.83599290780142 0.174338700296749 0.496513097551657 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 8/376 268/18639 0.0298507462686567 1.4797554779295 0.175720284579661 0.496513097551657 GO:0000146 microfilament motor activity 2/376 38/18639 0.0526315789473684 2.60904255319149 0.178282090899262 0.496513097551657 GO:0043531 ADP binding 2/376 38/18639 0.0526315789473684 2.60904255319149 0.178282090899262 0.496513097551657 GO:0141003 histone H2AX kinase activity 10/376 354/18639 0.0282485875706215 1.40033357374684 0.180182248662031 0.496513097551657 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/376 10/18639 0.1 4.95718085106383 0.18440695526133 0.496513097551657 GO:0004935 adrenergic receptor activity 1/376 10/18639 0.1 4.95718085106383 0.18440695526133 0.496513097551657 GO:0005381 iron ion transmembrane transporter activity 1/376 10/18639 0.1 4.95718085106383 0.18440695526133 0.496513097551657 GO:0005522 profilin binding 1/376 10/18639 0.1 4.95718085106383 0.18440695526133 0.496513097551657 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 1/376 10/18639 0.1 4.95718085106383 0.18440695526133 0.496513097551657 GO:0015187 glycine transmembrane transporter activity 1/376 10/18639 0.1 4.95718085106383 0.18440695526133 0.496513097551657 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/376 10/18639 0.1 4.95718085106383 0.18440695526133 0.496513097551657 GO:0019531 oxalate transmembrane transporter activity 1/376 10/18639 0.1 4.95718085106383 0.18440695526133 0.496513097551657 GO:0019911 structural constituent of myelin sheath 1/376 10/18639 0.1 4.95718085106383 0.18440695526133 0.496513097551657 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/376 10/18639 0.1 4.95718085106383 0.18440695526133 0.496513097551657 GO:0043121 neurotrophin binding 1/376 10/18639 0.1 4.95718085106383 0.18440695526133 0.496513097551657 GO:0043208 glycosphingolipid binding 1/376 10/18639 0.1 4.95718085106383 0.18440695526133 0.496513097551657 GO:0043295 glutathione binding 1/376 10/18639 0.1 4.95718085106383 0.18440695526133 0.496513097551657 GO:0051378 serotonin binding 1/376 10/18639 0.1 4.95718085106383 0.18440695526133 0.496513097551657 GO:0070097 delta-catenin binding 1/376 10/18639 0.1 4.95718085106383 0.18440695526133 0.496513097551657 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/376 10/18639 0.1 4.95718085106383 0.18440695526133 0.496513097551657 GO:0140135 mechanosensitive monoatomic cation channel activity 1/376 10/18639 0.1 4.95718085106383 0.18440695526133 0.496513097551657 GO:0140996 histone H3 kinase activity 10/376 357/18639 0.0280112044817927 1.38856606472376 0.186660001265819 0.496513097551657 GO:0016791 phosphatase activity 8/376 273/18639 0.0293040293040293 1.45265372924947 0.18811507952544 0.496513097551657 GO:0015144 carbohydrate transmembrane transporter activity 2/376 40/18639 0.05 2.47859042553192 0.192883010859141 0.496513097551657 GO:0140662 ATP-dependent protein folding chaperone 2/376 40/18639 0.05 2.47859042553192 0.192883010859141 0.496513097551657 GO:0035173 histone kinase activity 10/376 360/18639 0.0277777777777778 1.37699468085106 0.193241780925375 0.496513097551657 GO:0042578 phosphoric ester hydrolase activity 10/376 363/18639 0.0275482093663912 1.36561455952172 0.199924869225783 0.496513097551657 GO:0015175 neutral L-amino acid transmembrane transporter activity 2/376 41/18639 0.0487804878048781 2.41813700051894 0.200240870967219 0.496513097551657 GO:0016877 ligase activity, forming carbon-sulfur bonds 2/376 41/18639 0.0487804878048781 2.41813700051894 0.200240870967219 0.496513097551657 GO:0042169 SH2 domain binding 2/376 41/18639 0.0487804878048781 2.41813700051894 0.200240870967219 0.496513097551657 GO:0140318 protein transporter activity 2/376 41/18639 0.0487804878048781 2.41813700051894 0.200240870967219 0.496513097551657 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/376 11/18639 0.0909090909090909 4.50652804642166 0.20086854658785 0.496513097551657 GO:0005114 type II transforming growth factor beta receptor binding 1/376 11/18639 0.0909090909090909 4.50652804642166 0.20086854658785 0.496513097551657 GO:0008503 benzodiazepine receptor activity 1/376 11/18639 0.0909090909090909 4.50652804642166 0.20086854658785 0.496513097551657 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 1/376 11/18639 0.0909090909090909 4.50652804642166 0.20086854658785 0.496513097551657 GO:0016594 glycine binding 1/376 11/18639 0.0909090909090909 4.50652804642166 0.20086854658785 0.496513097551657 GO:0019215 intermediate filament binding 1/376 11/18639 0.0909090909090909 4.50652804642166 0.20086854658785 0.496513097551657 GO:0032050 clathrin heavy chain binding 1/376 11/18639 0.0909090909090909 4.50652804642166 0.20086854658785 0.496513097551657 GO:0034056 estrogen response element binding 1/376 11/18639 0.0909090909090909 4.50652804642166 0.20086854658785 0.496513097551657 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/376 11/18639 0.0909090909090909 4.50652804642166 0.20086854658785 0.496513097551657 GO:0043522 leucine zipper domain binding 1/376 11/18639 0.0909090909090909 4.50652804642166 0.20086854658785 0.496513097551657 GO:0045294 alpha-catenin binding 1/376 11/18639 0.0909090909090909 4.50652804642166 0.20086854658785 0.496513097551657 GO:0047676 arachidonate-CoA ligase activity 1/376 11/18639 0.0909090909090909 4.50652804642166 0.20086854658785 0.496513097551657 GO:0048185 activin binding 1/376 11/18639 0.0909090909090909 4.50652804642166 0.20086854658785 0.496513097551657 GO:0050786 RAGE receptor binding 1/376 11/18639 0.0909090909090909 4.50652804642166 0.20086854658785 0.496513097551657 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/376 11/18639 0.0909090909090909 4.50652804642166 0.20086854658785 0.496513097551657 GO:1900750 oligopeptide binding 1/376 11/18639 0.0909090909090909 4.50652804642166 0.20086854658785 0.496513097551657 GO:1990948 ubiquitin ligase inhibitor activity 1/376 11/18639 0.0909090909090909 4.50652804642166 0.20086854658785 0.496513097551657 GO:0101005 deubiquitinase activity 4/376 115/18639 0.0347826086956522 1.72423681776133 0.202824238519193 0.499588124352539 GO:0008307 structural constituent of muscle 2/376 42/18639 0.0476190476190476 2.36056231003039 0.207631014190946 0.504414312579661 GO:0033293 monocarboxylic acid binding 3/376 79/18639 0.0379746835443038 1.88247374091032 0.213680385913429 0.504414312579661 GO:0048156 tau protein binding 2/376 43/18639 0.0465116279069767 2.30566551212271 0.215049158421618 0.504414312579661 GO:0004300 enoyl-CoA hydratase activity 1/376 12/18639 0.0833333333333333 4.13098404255319 0.216998749856208 0.504414312579661 GO:0004859 phospholipase inhibitor activity 1/376 12/18639 0.0833333333333333 4.13098404255319 0.216998749856208 0.504414312579661 GO:0005025 transforming growth factor beta receptor activity, type I 1/376 12/18639 0.0833333333333333 4.13098404255319 0.216998749856208 0.504414312579661 GO:0005026 transforming growth factor beta receptor activity, type II 1/376 12/18639 0.0833333333333333 4.13098404255319 0.216998749856208 0.504414312579661 GO:0008179 adenylate cyclase binding 1/376 12/18639 0.0833333333333333 4.13098404255319 0.216998749856208 0.504414312579661 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/376 12/18639 0.0833333333333333 4.13098404255319 0.216998749856208 0.504414312579661 GO:0008504 monoamine transmembrane transporter activity 1/376 12/18639 0.0833333333333333 4.13098404255319 0.216998749856208 0.504414312579661 GO:0008603 cAMP-dependent protein kinase regulator activity 1/376 12/18639 0.0833333333333333 4.13098404255319 0.216998749856208 0.504414312579661 GO:0016208 AMP binding 1/376 12/18639 0.0833333333333333 4.13098404255319 0.216998749856208 0.504414312579661 GO:0016361 activin receptor activity, type I 1/376 12/18639 0.0833333333333333 4.13098404255319 0.216998749856208 0.504414312579661 GO:0016362 activin receptor activity, type II 1/376 12/18639 0.0833333333333333 4.13098404255319 0.216998749856208 0.504414312579661 GO:0017002 activin receptor activity 1/376 12/18639 0.0833333333333333 4.13098404255319 0.216998749856208 0.504414312579661 GO:0070008 serine-type exopeptidase activity 1/376 12/18639 0.0833333333333333 4.13098404255319 0.216998749856208 0.504414312579661 GO:0070410 co-SMAD binding 1/376 12/18639 0.0833333333333333 4.13098404255319 0.216998749856208 0.504414312579661 GO:0099106 ion channel regulator activity 5/376 160/18639 0.03125 1.54911901595745 0.222283115070529 0.513778975583801 GO:0001223 transcription coactivator binding 2/376 44/18639 0.0454545454545455 2.25326402321083 0.222491180309794 0.513778975583801 GO:0004465 lipoprotein lipase activity 1/376 13/18639 0.0769230769230769 3.81321603927987 0.232804218802043 0.522135979549629 GO:0005338 nucleotide-sugar transmembrane transporter activity 1/376 13/18639 0.0769230769230769 3.81321603927987 0.232804218802043 0.522135979549629 GO:0008035 high-density lipoprotein particle binding 1/376 13/18639 0.0769230769230769 3.81321603927987 0.232804218802043 0.522135979549629 GO:0039706 co-receptor binding 1/376 13/18639 0.0769230769230769 3.81321603927987 0.232804218802043 0.522135979549629 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 1/376 13/18639 0.0769230769230769 3.81321603927987 0.232804218802043 0.522135979549629 GO:0061459 L-arginine transmembrane transporter activity 1/376 13/18639 0.0769230769230769 3.81321603927987 0.232804218802043 0.522135979549629 GO:0071837 HMG box domain binding 1/376 13/18639 0.0769230769230769 3.81321603927987 0.232804218802043 0.522135979549629 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/376 13/18639 0.0769230769230769 3.81321603927987 0.232804218802043 0.522135979549629 GO:0140666 annealing activity 1/376 13/18639 0.0769230769230769 3.81321603927987 0.232804218802043 0.522135979549629 GO:0005254 chloride channel activity 3/376 83/18639 0.036144578313253 1.79175211484235 0.234926475831053 0.525217789915284 GO:0004180 carboxypeptidase activity 2/376 46/18639 0.0434782608695652 2.15529602220166 0.237431129775942 0.529132232072099 GO:0001784 phosphotyrosine residue binding 2/376 47/18639 0.0425531914893617 2.10943866002716 0.244921563351856 0.536309583655992 GO:0043495 protein-membrane adaptor activity 2/376 47/18639 0.0425531914893617 2.10943866002716 0.244921563351856 0.536309583655992 GO:0051015 actin filament binding 6/376 209/18639 0.0287081339712919 1.42311411992263 0.247418630586337 0.536309583655992 GO:0004065 arylsulfatase activity 1/376 14/18639 0.0714285714285714 3.54084346504559 0.248291473914811 0.536309583655992 GO:0008191 metalloendopeptidase inhibitor activity 1/376 14/18639 0.0714285714285714 3.54084346504559 0.248291473914811 0.536309583655992 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/376 14/18639 0.0714285714285714 3.54084346504559 0.248291473914811 0.536309583655992 GO:0043176 amine binding 1/376 14/18639 0.0714285714285714 3.54084346504559 0.248291473914811 0.536309583655992 GO:0098821 BMP receptor activity 1/376 14/18639 0.0714285714285714 3.54084346504559 0.248291473914811 0.536309583655992 GO:1901474 azole transmembrane transporter activity 1/376 14/18639 0.0714285714285714 3.54084346504559 0.248291473914811 0.536309583655992 GO:1901612 cardiolipin binding 1/376 14/18639 0.0714285714285714 3.54084346504559 0.248291473914811 0.536309583655992 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 3/376 86/18639 0.0348837209302326 1.72924913409203 0.251096421436427 0.539223811602312 GO:0016247 channel regulator activity 5/376 168/18639 0.0297619047619048 1.475351443769 0.252076454858938 0.539223811602312 GO:0019783 ubiquitin-like protein peptidase activity 4/376 127/18639 0.031496062992126 1.56131680348467 0.254421027294153 0.539223811602312 GO:0141108 transporter regulator activity 5/376 170/18639 0.0294117647058824 1.45799436795995 0.259678976764012 0.539223811602312 GO:0035591 signaling adaptor activity 4/376 129/18639 0.0310077519379845 1.53711034141514 0.263280654859956 0.539223811602312 GO:0000774 adenyl-nucleotide exchange factor activity 1/376 15/18639 0.0666666666666667 3.30478723404255 0.263466905099135 0.539223811602312 GO:0004089 carbonate dehydratase activity 1/376 15/18639 0.0666666666666667 3.30478723404255 0.263466905099135 0.539223811602312 GO:0004467 long-chain fatty acid-CoA ligase activity 1/376 15/18639 0.0666666666666667 3.30478723404255 0.263466905099135 0.539223811602312 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 1/376 15/18639 0.0666666666666667 3.30478723404255 0.263466905099135 0.539223811602312 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 1/376 15/18639 0.0666666666666667 3.30478723404255 0.263466905099135 0.539223811602312 GO:0015556 C4-dicarboxylate transmembrane transporter activity 1/376 15/18639 0.0666666666666667 3.30478723404255 0.263466905099135 0.539223811602312 GO:0016846 carbon-sulfur lyase activity 1/376 15/18639 0.0666666666666667 3.30478723404255 0.263466905099135 0.539223811602312 GO:0033130 acetylcholine receptor binding 1/376 15/18639 0.0666666666666667 3.30478723404255 0.263466905099135 0.539223811602312 GO:0034483 heparan sulfate sulfotransferase activity 1/376 15/18639 0.0666666666666667 3.30478723404255 0.263466905099135 0.539223811602312 GO:0048531 beta-1,3-galactosyltransferase activity 1/376 15/18639 0.0666666666666667 3.30478723404255 0.263466905099135 0.539223811602312 GO:0055105 ubiquitin-protein transferase inhibitor activity 1/376 15/18639 0.0666666666666667 3.30478723404255 0.263466905099135 0.539223811602312 GO:0120283 protein serine/threonine kinase binding 1/376 15/18639 0.0666666666666667 3.30478723404255 0.263466905099135 0.539223811602312 GO:0140776 protein-containing complex destabilizing activity 1/376 15/18639 0.0666666666666667 3.30478723404255 0.263466905099135 0.539223811602312 GO:0015605 organophosphate ester transmembrane transporter activity 2/376 50/18639 0.04 1.98287234042553 0.267432695994626 0.544777197843803 GO:0016298 lipase activity 4/376 130/18639 0.0307692307692308 1.52528641571195 0.267732383555715 0.544777197843803 GO:0016597 amino acid binding 2/376 51/18639 0.0392156862745098 1.94399249061327 0.274938800388816 0.550401170554246 GO:0030544 Hsp70 protein binding 2/376 51/18639 0.0392156862745098 1.94399249061327 0.274938800388816 0.550401170554246 GO:0000062 fatty-acyl-CoA binding 1/376 16/18639 0.0625 3.09823803191489 0.27833677428313 0.550401170554246 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 1/376 16/18639 0.0625 3.09823803191489 0.27833677428313 0.550401170554246 GO:0015378 sodium:chloride symporter activity 1/376 16/18639 0.0625 3.09823803191489 0.27833677428313 0.550401170554246 GO:0015562 efflux transmembrane transporter activity 1/376 16/18639 0.0625 3.09823803191489 0.27833677428313 0.550401170554246 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/376 16/18639 0.0625 3.09823803191489 0.27833677428313 0.550401170554246 GO:0022858 alanine transmembrane transporter activity 1/376 16/18639 0.0625 3.09823803191489 0.27833677428313 0.550401170554246 GO:0030275 LRR domain binding 1/376 16/18639 0.0625 3.09823803191489 0.27833677428313 0.550401170554246 GO:0055102 lipase inhibitor activity 1/376 16/18639 0.0625 3.09823803191489 0.27833677428313 0.550401170554246 GO:0051087 protein-folding chaperone binding 4/376 134/18639 0.0298507462686567 1.4797554779295 0.285667346675604 0.560274842011699 GO:0005544 calcium-dependent phospholipid binding 2/376 53/18639 0.0377358490566038 1.87063428342031 0.289936344881813 0.560274842011699 GO:1901505 carbohydrate derivative transmembrane transporter activity 2/376 53/18639 0.0377358490566038 1.87063428342031 0.289936344881813 0.560274842011699 GO:0005319 lipid transporter activity 5/376 178/18639 0.0280898876404494 1.3924665311977 0.290586335698091 0.560274842011699 GO:0008429 phosphatidylethanolamine binding 1/376 17/18639 0.0588235294117647 2.9159887359199 0.292907217974777 0.560274842011699 GO:0008484 sulfuric ester hydrolase activity 1/376 17/18639 0.0588235294117647 2.9159887359199 0.292907217974777 0.560274842011699 GO:0016018 cyclosporin A binding 1/376 17/18639 0.0588235294117647 2.9159887359199 0.292907217974777 0.560274842011699 GO:0016805 dipeptidase activity 1/376 17/18639 0.0588235294117647 2.9159887359199 0.292907217974777 0.560274842011699 GO:0030548 acetylcholine receptor regulator activity 1/376 17/18639 0.0588235294117647 2.9159887359199 0.292907217974777 0.560274842011699 GO:0038191 neuropilin binding 1/376 17/18639 0.0588235294117647 2.9159887359199 0.292907217974777 0.560274842011699 GO:1901567 fatty acid derivative binding 1/376 17/18639 0.0588235294117647 2.9159887359199 0.292907217974777 0.560274842011699 GO:1990226 histone methyltransferase binding 1/376 17/18639 0.0588235294117647 2.9159887359199 0.292907217974777 0.560274842011699 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 2/376 54/18639 0.037037037037037 1.83599290780142 0.297422124398459 0.563161295329828 GO:0050661 NADP binding 2/376 54/18639 0.037037037037037 1.83599290780142 0.297422124398459 0.563161295329828 GO:0005543 phospholipid binding 12/376 497/18639 0.0241448692152917 1.19690483325485 0.303465405549262 0.563161295329828 GO:0004896 cytokine receptor activity 3/376 96/18639 0.03125 1.54911901595745 0.305919843584076 0.563161295329828 GO:0008409 5'-3' exonuclease activity 1/376 18/18639 0.0555555555555556 2.75398936170213 0.30718424976736 0.563161295329828 GO:0015373 monoatomic anion:sodium symporter activity 1/376 18/18639 0.0555555555555556 2.75398936170213 0.30718424976736 0.563161295329828 GO:0017075 syntaxin-1 binding 1/376 18/18639 0.0555555555555556 2.75398936170213 0.30718424976736 0.563161295329828 GO:0022851 GABA-gated chloride ion channel activity 1/376 18/18639 0.0555555555555556 2.75398936170213 0.30718424976736 0.563161295329828 GO:0031690 adrenergic receptor binding 1/376 18/18639 0.0555555555555556 2.75398936170213 0.30718424976736 0.563161295329828 GO:0035615 clathrin adaptor activity 1/376 18/18639 0.0555555555555556 2.75398936170213 0.30718424976736 0.563161295329828 GO:0070628 proteasome binding 1/376 18/18639 0.0555555555555556 2.75398936170213 0.30718424976736 0.563161295329828 GO:0098641 cadherin binding involved in cell-cell adhesion 1/376 18/18639 0.0555555555555556 2.75398936170213 0.30718424976736 0.563161295329828 GO:0099602 neurotransmitter receptor regulator activity 1/376 18/18639 0.0555555555555556 2.75398936170213 0.30718424976736 0.563161295329828 GO:1901611 phosphatidylglycerol binding 1/376 18/18639 0.0555555555555556 2.75398936170213 0.30718424976736 0.563161295329828 GO:1990381 ubiquitin-specific protease binding 1/376 18/18639 0.0555555555555556 2.75398936170213 0.30718424976736 0.563161295329828 GO:0005096 GTPase activator activity 7/376 271/18639 0.025830258302583 1.28045261835597 0.307251817822399 0.563161295329828 GO:0015932 nucleobase-containing compound transmembrane transporter activity 2/376 57/18639 0.0350877192982456 1.73936170212766 0.319795923204688 0.576634223739341 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/376 19/18639 0.0526315789473684 2.60904255319149 0.321173762794989 0.576634223739341 GO:0004890 GABA-A receptor activity 1/376 19/18639 0.0526315789473684 2.60904255319149 0.321173762794989 0.576634223739341 GO:0005346 purine ribonucleotide transmembrane transporter activity 1/376 19/18639 0.0526315789473684 2.60904255319149 0.321173762794989 0.576634223739341 GO:0031420 alkali metal ion binding 1/376 19/18639 0.0526315789473684 2.60904255319149 0.321173762794989 0.576634223739341 GO:0042834 peptidoglycan binding 1/376 19/18639 0.0526315789473684 2.60904255319149 0.321173762794989 0.576634223739341 GO:0097001 ceramide binding 1/376 19/18639 0.0526315789473684 2.60904255319149 0.321173762794989 0.576634223739341 GO:0120227 acyl-CoA binding 1/376 19/18639 0.0526315789473684 2.60904255319149 0.321173762794989 0.576634223739341 GO:0019903 protein phosphatase binding 4/376 144/18639 0.0277777777777778 1.37699468085106 0.331139180825134 0.584793123287845 GO:0001786 phosphatidylserine binding 2/376 59/18639 0.0338983050847458 1.68040028849621 0.334618023315693 0.584793123287845 GO:0015459 potassium channel regulator activity 2/376 59/18639 0.0338983050847458 1.68040028849621 0.334618023315693 0.584793123287845 GO:0031593 polyubiquitin modification-dependent protein binding 2/376 59/18639 0.0338983050847458 1.68040028849621 0.334618023315693 0.584793123287845 GO:0045309 protein phosphorylated amino acid binding 2/376 59/18639 0.0338983050847458 1.68040028849621 0.334618023315693 0.584793123287845 GO:0001614 purinergic nucleotide receptor activity 1/376 20/18639 0.05 2.47859042553192 0.334881532139193 0.584793123287845 GO:0001972 retinoic acid binding 1/376 20/18639 0.05 2.47859042553192 0.334881532139193 0.584793123287845 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1/376 20/18639 0.05 2.47859042553192 0.334881532139193 0.584793123287845 GO:0005326 neurotransmitter transmembrane transporter activity 1/376 20/18639 0.05 2.47859042553192 0.334881532139193 0.584793123287845 GO:0015095 magnesium ion transmembrane transporter activity 1/376 20/18639 0.05 2.47859042553192 0.334881532139193 0.584793123287845 GO:0016502 nucleotide receptor activity 1/376 20/18639 0.05 2.47859042553192 0.334881532139193 0.584793123287845 GO:0008194 UDP-glycosyltransferase activity 4/376 145/18639 0.0275862068965517 1.36749816581071 0.335716372157048 0.584796261176794 GO:0019902 phosphatase binding 5/376 190/18639 0.0263157894736842 1.30452127659574 0.338009960196651 0.587334138757547 GO:0015171 amino acid transmembrane transporter activity 3/376 102/18639 0.0294117647058824 1.45799436795995 0.339093646278802 0.587762320216591 GO:0005253 monoatomic anion channel activity 3/376 103/18639 0.029126213592233 1.44383908283413 0.344619019024708 0.590939311320261 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/376 21/18639 0.0476190476190476 2.36056231003039 0.348313217187566 0.590939311320261 GO:0015125 bile acid transmembrane transporter activity 1/376 21/18639 0.0476190476190476 2.36056231003039 0.348313217187566 0.590939311320261 GO:0015174 basic amino acid transmembrane transporter activity 1/376 21/18639 0.0476190476190476 2.36056231003039 0.348313217187566 0.590939311320261 GO:0035613 RNA stem-loop binding 1/376 21/18639 0.0476190476190476 2.36056231003039 0.348313217187566 0.590939311320261 GO:0061891 calcium ion sensor activity 1/376 21/18639 0.0476190476190476 2.36056231003039 0.348313217187566 0.590939311320261 GO:0140312 cargo adaptor activity 1/376 21/18639 0.0476190476190476 2.36056231003039 0.348313217187566 0.590939311320261 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 2/376 61/18639 0.0327868852459016 1.62530519707011 0.349344464669385 0.590939311320261 GO:0016836 hydro-lyase activity 2/376 61/18639 0.0327868852459016 1.62530519707011 0.349344464669385 0.590939311320261 GO:0019905 syntaxin binding 2/376 61/18639 0.0327868852459016 1.62530519707011 0.349344464669385 0.590939311320261 GO:0015179 L-amino acid transmembrane transporter activity 2/376 62/18639 0.032258064516129 1.59909059711736 0.356666762459662 0.598478781815273 GO:0019207 kinase regulator activity 7/376 287/18639 0.024390243902439 1.20906850025947 0.359297292659627 0.598478781815273 GO:0008970 phospholipase A1 activity 1/376 22/18639 0.0454545454545455 2.25326402321083 0.361474363945407 0.598478781815273 GO:0015377 chloride:monoatomic cation symporter activity 1/376 22/18639 0.0454545454545455 2.25326402321083 0.361474363945407 0.598478781815273 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 1/376 22/18639 0.0454545454545455 2.25326402321083 0.361474363945407 0.598478781815273 GO:0034062 5'-3' RNA polymerase activity 1/376 22/18639 0.0454545454545455 2.25326402321083 0.361474363945407 0.598478781815273 GO:0061133 endopeptidase activator activity 1/376 22/18639 0.0454545454545455 2.25326402321083 0.361474363945407 0.598478781815273 GO:0097747 RNA polymerase activity 1/376 22/18639 0.0454545454545455 2.25326402321083 0.361474363945407 0.598478781815273 GO:0140784 metal ion sensor activity 1/376 22/18639 0.0454545454545455 2.25326402321083 0.361474363945407 0.598478781815273 GO:0016758 hexosyltransferase activity 5/376 197/18639 0.0253807106598985 1.2581677286964 0.365981053968583 0.60451458796693 GO:0000295 adenine nucleotide transmembrane transporter activity 1/376 23/18639 0.0434782608695652 2.15529602220166 0.374370407301293 0.609763401219275 GO:0005283 amino acid:sodium symporter activity 1/376 23/18639 0.0434782608695652 2.15529602220166 0.374370407301293 0.609763401219275 GO:0016917 GABA receptor activity 1/376 23/18639 0.0434782608695652 2.15529602220166 0.374370407301293 0.609763401219275 GO:0031681 G-protein beta-subunit binding 1/376 23/18639 0.0434782608695652 2.15529602220166 0.374370407301293 0.609763401219275 GO:0070577 lysine-acetylated histone binding 1/376 23/18639 0.0434782608695652 2.15529602220166 0.374370407301293 0.609763401219275 GO:0099186 structural constituent of postsynapse 1/376 23/18639 0.0434782608695652 2.15529602220166 0.374370407301293 0.609763401219275 GO:0004620 phospholipase activity 3/376 109/18639 0.0275229357798165 1.36436170212766 0.377651699714555 0.613684012036151 GO:0004806 triacylglycerol lipase activity 1/376 24/18639 0.0416666666666667 2.0654920212766 0.387006673247507 0.617451555953977 GO:0035035 histone acetyltransferase binding 1/376 24/18639 0.0416666666666667 2.0654920212766 0.387006673247507 0.617451555953977 GO:0042625 ATPase-coupled ion transmembrane transporter activity 1/376 24/18639 0.0416666666666667 2.0654920212766 0.387006673247507 0.617451555953977 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 1/376 24/18639 0.0416666666666667 2.0654920212766 0.387006673247507 0.617451555953977 GO:0046961 proton-transporting ATPase activity, rotational mechanism 1/376 24/18639 0.0416666666666667 2.0654920212766 0.387006673247507 0.617451555953977 GO:0048027 mRNA 5'-UTR binding 1/376 24/18639 0.0416666666666667 2.0654920212766 0.387006673247507 0.617451555953977 GO:0050699 WW domain binding 1/376 24/18639 0.0416666666666667 2.0654920212766 0.387006673247507 0.617451555953977 GO:0140033 acetylation-dependent protein binding 1/376 24/18639 0.0416666666666667 2.0654920212766 0.387006673247507 0.617451555953977 GO:1902936 phosphatidylinositol bisphosphate binding 3/376 111/18639 0.027027027027027 1.33977860839563 0.388593275899032 0.618577051431112 GO:0005200 structural constituent of cytoskeleton 3/376 112/18639 0.0267857142857143 1.3278162993921 0.394046865236966 0.621107794963557 GO:0001848 complement binding 1/376 25/18639 0.04 1.98287234042553 0.399388381056206 0.621107794963557 GO:0004709 MAP kinase kinase kinase activity 1/376 25/18639 0.04 1.98287234042553 0.399388381056206 0.621107794963557 GO:0005537 D-mannose binding 1/376 25/18639 0.04 1.98287234042553 0.399388381056206 0.621107794963557 GO:0015296 monoatomic anion:monoatomic cation symporter activity 1/376 25/18639 0.04 1.98287234042553 0.399388381056206 0.621107794963557 GO:0015662 P-type ion transporter activity 1/376 25/18639 0.04 1.98287234042553 0.399388381056206 0.621107794963557 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 1/376 25/18639 0.04 1.98287234042553 0.399388381056206 0.621107794963557 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/376 25/18639 0.04 1.98287234042553 0.399388381056206 0.621107794963557 GO:0120020 cholesterol transfer activity 1/376 25/18639 0.04 1.98287234042553 0.399388381056206 0.621107794963557 GO:0140358 P-type transmembrane transporter activity 1/376 25/18639 0.04 1.98287234042553 0.399388381056206 0.621107794963557 GO:1990841 promoter-specific chromatin binding 2/376 68/18639 0.0294117647058824 1.45799436795995 0.399915560289925 0.621107794963557 GO:0002039 p53 binding 2/376 69/18639 0.0289855072463768 1.43686401480111 0.406994824016746 0.626653998002992 GO:0019887 protein kinase regulator activity 6/376 255/18639 0.0235294117647059 1.16639549436796 0.409700005307778 0.626653998002992 GO:0001221 transcription coregulator binding 3/376 115/18639 0.0260869565217391 1.293177613321 0.410328438849 0.626653998002992 GO:0017124 SH3 domain binding 3/376 115/18639 0.0260869565217391 1.293177613321 0.410328438849 0.626653998002992 GO:0004529 DNA exonuclease activity 1/376 26/18639 0.0384615384615385 1.90660801963993 0.411520645412221 0.626653998002992 GO:0005112 Notch binding 1/376 26/18639 0.0384615384615385 1.90660801963993 0.411520645412221 0.626653998002992 GO:0005160 transforming growth factor beta receptor binding 1/376 26/18639 0.0384615384615385 1.90660801963993 0.411520645412221 0.626653998002992 GO:0015216 purine nucleotide transmembrane transporter activity 1/376 26/18639 0.0384615384615385 1.90660801963993 0.411520645412221 0.626653998002992 GO:0030247 polysaccharide binding 1/376 26/18639 0.0384615384615385 1.90660801963993 0.411520645412221 0.626653998002992 GO:0140299 molecular sensor activity 2/376 71/18639 0.028169014084507 1.39638897213066 0.421030407225461 0.639210219159882 GO:0015081 sodium ion transmembrane transporter activity 4/376 164/18639 0.024390243902439 1.20906850025947 0.422475130763581 0.639210219159882 GO:0046873 metal ion transmembrane transporter activity 10/376 450/18639 0.0222222222222222 1.10159574468085 0.423021551488515 0.639210219159882 GO:0005385 zinc ion transmembrane transporter activity 1/376 27/18639 0.037037037037037 1.83599290780142 0.423408478503341 0.639210219159882 GO:0043539 protein serine/threonine kinase activator activity 2/376 73/18639 0.0273972602739726 1.35813174001749 0.434894093336973 0.649808229856146 GO:0046625 sphingolipid binding 1/376 28/18639 0.0357142857142857 1.7704217325228 0.43505679206893 0.649808229856146 GO:0050698 proteoglycan sulfotransferase activity 1/376 28/18639 0.0357142857142857 1.7704217325228 0.43505679206893 0.649808229856146 GO:0051393 alpha-actinin binding 1/376 28/18639 0.0357142857142857 1.7704217325228 0.43505679206893 0.649808229856146 GO:0051959 dynein light intermediate chain binding 1/376 28/18639 0.0357142857142857 1.7704217325228 0.43505679206893 0.649808229856146 GO:0048029 monosaccharide binding 2/376 74/18639 0.027027027027027 1.33977860839563 0.441758726805184 0.65706964441135 GO:0106310 protein serine kinase activity 8/376 361/18639 0.0221606648199446 1.09854423292273 0.444086051310381 0.65706964441135 GO:0004629 phospholipase C activity 1/376 29/18639 0.0344827586206897 1.70937270726339 0.446470399407712 0.65706964441135 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/376 29/18639 0.0344827586206897 1.70937270726339 0.446470399407712 0.65706964441135 GO:0005416 amino acid:monoatomic cation symporter activity 1/376 29/18639 0.0344827586206897 1.70937270726339 0.446470399407712 0.65706964441135 GO:0035250 UDP-galactosyltransferase activity 1/376 29/18639 0.0344827586206897 1.70937270726339 0.446470399407712 0.65706964441135 GO:0097472 cyclin-dependent protein kinase activity 1/376 29/18639 0.0344827586206897 1.70937270726339 0.446470399407712 0.65706964441135 GO:0003725 double-stranded RNA binding 2/376 75/18639 0.0266666666666667 1.32191489361702 0.448577210923625 0.657413783023768 GO:0044183 protein folding chaperone 2/376 75/18639 0.0266666666666667 1.32191489361702 0.448577210923625 0.657413783023768 GO:0001965 G-protein alpha-subunit binding 1/376 30/18639 0.0333333333333333 1.65239361702128 0.457654017345525 0.666541743104893 GO:0015215 nucleotide transmembrane transporter activity 1/376 30/18639 0.0333333333333333 1.65239361702128 0.457654017345525 0.666541743104893 GO:0031210 phosphatidylcholine binding 1/376 30/18639 0.0333333333333333 1.65239361702128 0.457654017345525 0.666541743104893 GO:0140030 modification-dependent protein binding 4/376 173/18639 0.023121387283237 1.14616898290493 0.46273874572341 0.672551965834025 GO:0042826 histone deacetylase binding 3/376 127/18639 0.0236220472440945 1.1709876026135 0.473897331377123 0.687346955840372 GO:0016835 carbon-oxygen lyase activity 2/376 79/18639 0.0253164556962025 1.25498249394021 0.475371805272778 0.688063932580392 GO:0008378 galactosyltransferase activity 1/376 32/18639 0.03125 1.54911901595745 0.479349681489853 0.688146168519176 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/376 32/18639 0.03125 1.54911901595745 0.479349681489853 0.688146168519176 GO:0043425 bHLH transcription factor binding 1/376 32/18639 0.03125 1.54911901595745 0.479349681489853 0.688146168519176 GO:0120015 sterol transfer activity 1/376 32/18639 0.03125 1.54911901595745 0.479349681489853 0.688146168519176 GO:0048306 calcium-dependent protein binding 2/376 80/18639 0.025 1.23929521276596 0.481946628648758 0.690462312880465 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 1/376 33/18639 0.0303030303030303 1.50217601547389 0.489870696148843 0.696132041895724 GO:0042923 neuropeptide binding 1/376 33/18639 0.0303030303030303 1.50217601547389 0.489870696148843 0.696132041895724 GO:0071889 14-3-3 protein binding 1/376 33/18639 0.0303030303030303 1.50217601547389 0.489870696148843 0.696132041895724 GO:0140416 transcription regulator inhibitor activity 1/376 33/18639 0.0303030303030303 1.50217601547389 0.489870696148843 0.696132041895724 GO:0000287 magnesium ion binding 5/376 230/18639 0.0217391304347826 1.07764801110083 0.496138424910935 0.703614493510054 GO:0030246 carbohydrate binding 6/376 280/18639 0.0214285714285714 1.06225303951368 0.498252668132081 0.705072535561678 GO:0015020 glucuronosyltransferase activity 1/376 34/18639 0.0294117647058824 1.45799436795995 0.500179661979652 0.705072535561678 GO:0030332 cyclin binding 1/376 34/18639 0.0294117647058824 1.45799436795995 0.500179661979652 0.705072535561678 GO:0016229 steroid dehydrogenase activity 1/376 35/18639 0.0285714285714286 1.41633738601824 0.510280841613925 0.71787004170937 GO:1901981 phosphatidylinositol phosphate binding 4/376 185/18639 0.0216216216216216 1.0718228867165 0.514789164335412 0.722763986726918 GO:0055106 ubiquitin-protein transferase regulator activity 1/376 36/18639 0.0277777777777778 1.37699468085106 0.520178412219879 0.724534217020545 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/376 36/18639 0.0277777777777778 1.37699468085106 0.520178412219879 0.724534217020545 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/376 36/18639 0.0277777777777778 1.37699468085106 0.520178412219879 0.724534217020545 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/376 36/18639 0.0277777777777778 1.37699468085106 0.520178412219879 0.724534217020545 GO:0008081 phosphoric diester hydrolase activity 2/376 87/18639 0.0229885057471264 1.13958180484226 0.526512052266126 0.729882077815351 GO:0030551 cyclic nucleotide binding 1/376 37/18639 0.027027027027027 1.33977860839563 0.529876467211296 0.729882077815351 GO:0042805 actinin binding 1/376 37/18639 0.027027027027027 1.33977860839563 0.529876467211296 0.729882077815351 GO:0070851 growth factor receptor binding 3/376 139/18639 0.0215827338129496 1.06989514771162 0.534160071589692 0.729882077815351 GO:0005501 retinoid binding 1/376 38/18639 0.0263157894736842 1.30452127659574 0.539379017922431 0.729882077815351 GO:0019840 isoprenoid binding 1/376 38/18639 0.0263157894736842 1.30452127659574 0.539379017922431 0.729882077815351 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 5/376 243/18639 0.0205761316872428 1.01999605988968 0.544832875693931 0.729882077815351 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/376 39/18639 0.0256410256410256 1.27107201309329 0.54868999524952 0.729882077815351 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/376 91/18639 0.021978021978022 1.08949029693711 0.550791351484659 0.729882077815351 GO:0004676 3-phosphoinositide-dependent protein kinase activity 5/376 245/18639 0.0204081632653061 1.0116695614416 0.552129043912121 0.729882077815351 GO:0004711 ribosomal protein S6 kinase activity 5/376 245/18639 0.0204081632653061 1.0116695614416 0.552129043912121 0.729882077815351 GO:0035175 histone H3S10 kinase activity 5/376 245/18639 0.0204081632653061 1.0116695614416 0.552129043912121 0.729882077815351 GO:0035979 histone H2AXS139 kinase activity 5/376 245/18639 0.0204081632653061 1.0116695614416 0.552129043912121 0.729882077815351 GO:0044022 histone H3S28 kinase activity 5/376 245/18639 0.0204081632653061 1.0116695614416 0.552129043912121 0.729882077815351 GO:0044023 histone H4S1 kinase activity 5/376 245/18639 0.0204081632653061 1.0116695614416 0.552129043912121 0.729882077815351 GO:0044024 histone H2AS1 kinase activity 5/376 245/18639 0.0204081632653061 1.0116695614416 0.552129043912121 0.729882077815351 GO:0044025 histone H2BS14 kinase activity 5/376 245/18639 0.0204081632653061 1.0116695614416 0.552129043912121 0.729882077815351 GO:0072354 histone H3T3 kinase activity 5/376 245/18639 0.0204081632653061 1.0116695614416 0.552129043912121 0.729882077815351 GO:0072371 histone H2AS121 kinase activity 5/376 245/18639 0.0204081632653061 1.0116695614416 0.552129043912121 0.729882077815351 GO:0072518 Rho-dependent protein serine/threonine kinase activity 5/376 245/18639 0.0204081632653061 1.0116695614416 0.552129043912121 0.729882077815351 GO:0140823 histone H2BS36 kinase activity 5/376 245/18639 0.0204081632653061 1.0116695614416 0.552129043912121 0.729882077815351 GO:0140855 histone H3S57 kinase activity 5/376 245/18639 0.0204081632653061 1.0116695614416 0.552129043912121 0.729882077815351 GO:0140995 histone H2A kinase activity 5/376 245/18639 0.0204081632653061 1.0116695614416 0.552129043912121 0.729882077815351 GO:0140997 histone H4 kinase activity 5/376 245/18639 0.0204081632653061 1.0116695614416 0.552129043912121 0.729882077815351 GO:0140998 histone H2B kinase activity 5/376 245/18639 0.0204081632653061 1.0116695614416 0.552129043912121 0.729882077815351 GO:1990244 histone H2AT120 kinase activity 5/376 245/18639 0.0204081632653061 1.0116695614416 0.552129043912121 0.729882077815351 GO:0004677 DNA-dependent protein kinase activity 5/376 246/18639 0.0203252032520325 1.00755708354956 0.555755888681085 0.729882077815351 GO:0140857 histone H3T45 kinase activity 5/376 246/18639 0.0203252032520325 1.00755708354956 0.555755888681085 0.729882077815351 GO:0052689 carboxylic ester hydrolase activity 2/376 92/18639 0.0217391304347826 1.07764801110083 0.556722945496527 0.729882077815351 GO:0030331 nuclear estrogen receptor binding 1/376 40/18639 0.025 1.23929521276596 0.557813251259529 0.729882077815351 GO:0050997 quaternary ammonium group binding 1/376 40/18639 0.025 1.23929521276596 0.557813251259529 0.729882077815351 GO:0071949 FAD binding 1/376 40/18639 0.025 1.23929521276596 0.557813251259529 0.729882077815351 GO:0035402 histone H3T11 kinase activity 5/376 247/18639 0.0202429149797571 1.00347790507365 0.559368316046522 0.729882077815351 GO:0035403 histone H3T6 kinase activity 5/376 247/18639 0.0202429149797571 1.00347790507365 0.559368316046522 0.729882077815351 GO:0051219 phosphoprotein binding 2/376 93/18639 0.021505376344086 1.06606039807824 0.56259879694725 0.731855980090822 GO:0004679 AMP-activated protein kinase activity 5/376 248/18639 0.0201612903225806 0.999431623198353 0.562966138531402 0.731855980090822 GO:0001530 lipopolysaccharide binding 1/376 41/18639 0.024390243902439 1.20906850025947 0.566752560766837 0.732707730494143 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 1/376 41/18639 0.024390243902439 1.20906850025947 0.566752560766837 0.732707730494143 GO:0008227 G protein-coupled amine receptor activity 1/376 41/18639 0.024390243902439 1.20906850025947 0.566752560766837 0.732707730494143 GO:0031625 ubiquitin protein ligase binding 6/376 302/18639 0.0198675496688742 0.984870367761026 0.572170335062636 0.738336150512741 GO:0016859 cis-trans isomerase activity 1/376 42/18639 0.0238095238095238 1.1802811550152 0.575511622878444 0.738336150512741 GO:0035198 miRNA binding 1/376 42/18639 0.0238095238095238 1.1802811550152 0.575511622878444 0.738336150512741 GO:0048487 beta-tubulin binding 1/376 42/18639 0.0238095238095238 1.1802811550152 0.575511622878444 0.738336150512741 GO:0016829 lyase activity 4/376 200/18639 0.02 0.991436170212766 0.576364972195131 0.738336150512741 GO:0008200 ion channel inhibitor activity 1/376 43/18639 0.0232558139534884 1.15283275606136 0.584094062508369 0.746369082580311 GO:0030594 neurotransmitter receptor activity 2/376 97/18639 0.0206185567010309 1.02209914454924 0.585541806264404 0.746369082580311 GO:0019842 vitamin binding 3/376 150/18639 0.02 0.991436170212766 0.585825305558051 0.746369082580311 GO:0042626 ATPase-coupled transmembrane transporter activity 2/376 98/18639 0.0204081632653061 1.0116695614416 0.591136963013047 0.750789547232853 GO:0016248 channel inhibitor activity 1/376 44/18639 0.0227272727272727 1.12663201160542 0.592503431861824 0.750789547232853 GO:0043014 alpha-tubulin binding 1/376 44/18639 0.0227272727272727 1.12663201160542 0.592503431861824 0.750789547232853 GO:0042605 peptide antigen binding 1/376 45/18639 0.0222222222222222 1.10159574468085 0.600743211889786 0.758492328680989 GO:0141110 transporter inhibitor activity 1/376 45/18639 0.0222222222222222 1.10159574468085 0.600743211889786 0.758492328680989 GO:0004386 helicase activity 3/376 155/18639 0.0193548387096774 0.959454358270419 0.608068761508712 0.765930830157 GO:0030291 protein serine/threonine kinase inhibitor activity 1/376 46/18639 0.0217391304347826 1.07764801110083 0.608816813714538 0.765930830157 GO:0140375 immune receptor activity 3/376 156/18639 0.0192307692307692 0.953304009819967 0.612421082753285 0.767748000159842 GO:0005504 fatty acid binding 1/376 47/18639 0.0212765957446809 1.05471933001358 0.61672758002677 0.767748000159842 GO:0061749 forked DNA-dependent helicase activity 1/376 47/18639 0.0212765957446809 1.05471933001358 0.61672758002677 0.767748000159842 GO:0099095 ligand-gated monoatomic anion channel activity 1/376 47/18639 0.0212765957446809 1.05471933001358 0.61672758002677 0.767748000159842 GO:1990518 single-stranded 3'-5' DNA helicase activity 1/376 47/18639 0.0212765957446809 1.05471933001358 0.61672758002677 0.767748000159842 GO:0046982 protein heterodimerization activity 7/376 369/18639 0.018970189701897 0.940386611312922 0.618136985008603 0.767748000159842 GO:0004722 protein serine/threonine phosphatase activity 2/376 103/18639 0.0194174757281553 0.962559388556083 0.618267733853429 0.767748000159842 GO:0008188 neuropeptide receptor activity 1/376 48/18639 0.0208333333333333 1.0327460106383 0.6244787864548 0.767748000159842 GO:0009378 four-way junction helicase activity 1/376 48/18639 0.0208333333333333 1.0327460106383 0.6244787864548 0.767748000159842 GO:0032266 phosphatidylinositol-3-phosphate binding 1/376 48/18639 0.0208333333333333 1.0327460106383 0.6244787864548 0.767748000159842 GO:0036121 double-stranded DNA helicase activity 1/376 48/18639 0.0208333333333333 1.0327460106383 0.6244787864548 0.767748000159842 GO:0038187 pattern recognition receptor activity 1/376 48/18639 0.0208333333333333 1.0327460106383 0.6244787864548 0.767748000159842 GO:0043138 3'-5' DNA helicase activity 1/376 48/18639 0.0208333333333333 1.0327460106383 0.6244787864548 0.767748000159842 GO:0016757 glycosyltransferase activity 5/376 267/18639 0.0187265917602996 0.92831102079847 0.628333956207701 0.771137128073087 GO:0001222 transcription corepressor binding 1/376 49/18639 0.0204081632653061 1.0116695614416 0.63207364290647 0.773023862927425 GO:0060590 ATPase regulator activity 1/376 49/18639 0.0204081632653061 1.0116695614416 0.63207364290647 0.773023862927425 GO:0000149 SNARE binding 2/376 106/18639 0.0188679245283019 0.935317141710157 0.63387183181044 0.77321563961999 GO:0044389 ubiquitin-like protein ligase binding 6/376 322/18639 0.0186335403726708 0.923698295229285 0.634433345329223 0.77321563961999 GO:0008083 growth factor activity 3/376 162/18639 0.0185185185185185 0.917996453900709 0.637849822491952 0.776032193049134 GO:0140297 DNA-binding transcription factor binding 9/376 488/18639 0.0184426229508197 0.914234173351936 0.654401308386913 0.794499967368963 GO:0030695 GTPase regulator activity 9/376 489/18639 0.0184049079754601 0.912364573815429 0.65677957350579 0.794499967368963 GO:0060589 nucleoside-triphosphatase regulator activity 9/376 490/18639 0.0183673469387755 0.910502605297438 0.659148504707407 0.794499967368963 GO:0004864 protein phosphatase inhibitor activity 1/376 53/18639 0.0188679245283019 0.935317141710157 0.660951539805519 0.794499967368963 GO:0008146 sulfotransferase activity 1/376 53/18639 0.0188679245283019 0.935317141710157 0.660951539805519 0.794499967368963 GO:0016860 intramolecular oxidoreductase activity 1/376 53/18639 0.0188679245283019 0.935317141710157 0.660951539805519 0.794499967368963 GO:0051018 protein kinase A binding 1/376 53/18639 0.0188679245283019 0.935317141710157 0.660951539805519 0.794499967368963 GO:0015485 cholesterol binding 1/376 54/18639 0.0185185185185185 0.917996453900709 0.667810585379237 0.798642301424573 GO:0051287 NAD binding 1/376 54/18639 0.0185185185185185 0.917996453900709 0.667810585379237 0.798642301424573 GO:0140463 chromatin-protein adaptor activity 1/376 54/18639 0.0185185185185185 0.917996453900709 0.667810585379237 0.798642301424573 GO:0140313 molecular sequestering activity 1/376 55/18639 0.0181818181818182 0.901305609284333 0.674531232131855 0.805307695504358 GO:0019212 phosphatase inhibitor activity 1/376 56/18639 0.0178571428571429 0.885210866261398 0.681116265317307 0.80818396452661 GO:0030170 pyridoxal phosphate binding 1/376 56/18639 0.0178571428571429 0.885210866261398 0.681116265317307 0.80818396452661 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 1/376 56/18639 0.0178571428571429 0.885210866261398 0.681116265317307 0.80818396452661 GO:0035091 phosphatidylinositol binding 5/376 284/18639 0.0176056338028169 0.87274310758166 0.6815454515666 0.80818396452661 GO:0005216 monoatomic ion channel activity 8/376 448/18639 0.0178571428571429 0.885210866261398 0.685753961321733 0.811803171750179 GO:0070279 vitamin B6 binding 1/376 57/18639 0.0175438596491228 0.86968085106383 0.687568414283603 0.812580853244258 GO:0017116 single-stranded DNA helicase activity 1/376 58/18639 0.0172413793103448 0.854686353631695 0.69389035359204 0.817300382922167 GO:0061980 regulatory RNA binding 1/376 58/18639 0.0172413793103448 0.854686353631695 0.69389035359204 0.817300382922167 GO:0005125 cytokine activity 4/376 234/18639 0.0170940170940171 0.847381342062193 0.697948235061382 0.82070294977067 GO:0070888 E-box binding 1/376 59/18639 0.0169491525423729 0.840200144248107 0.700084704114046 0.821838565699097 GO:0003697 single-stranded DNA binding 2/376 121/18639 0.0165289256198347 0.81936873571303 0.704466220804698 0.823069832384418 GO:0051082 unfolded protein binding 2/376 121/18639 0.0165289256198347 0.81936873571303 0.704466220804698 0.823069832384418 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 1/376 60/18639 0.0166666666666667 0.826196808510638 0.70615403410614 0.823069832384418 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 1/376 60/18639 0.0166666666666667 0.826196808510638 0.70615403410614 0.823069832384418 GO:0016853 isomerase activity 3/376 180/18639 0.0166666666666667 0.826196808510638 0.706995881663538 0.823069832384418 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/376 122/18639 0.0163934426229508 0.812652598535054 0.708744746888411 0.823210409030194 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 6/376 349/18639 0.0171919770773639 0.852237395598366 0.709461962198387 0.823210409030194 GO:0001664 G protein-coupled receptor binding 5/376 297/18639 0.0168350168350168 0.834542230818827 0.718641950149641 0.832486219480277 GO:0022824 transmitter-gated monoatomic ion channel activity 1/376 63/18639 0.0158730158730159 0.786854103343465 0.723636816220878 0.835514876623448 GO:0022835 transmitter-gated channel activity 1/376 63/18639 0.0158730158730159 0.786854103343465 0.723636816220878 0.835514876623448 GO:0004536 DNA nuclease activity 1/376 64/18639 0.015625 0.774559507978723 0.729230730793496 0.840591088697922 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 2/376 128/18639 0.015625 0.774559507978723 0.733340909974382 0.843943145577076 GO:0120013 lipid transfer activity 1/376 65/18639 0.0153846153846154 0.762643207855974 0.734711713039614 0.844136861790195 GO:0016798 hydrolase activity, acting on glycosyl bonds 2/376 130/18639 0.0153846153846154 0.762643207855974 0.74113874451408 0.850129736354386 GO:0005262 calcium channel activity 2/376 131/18639 0.0152671755725191 0.756821503979211 0.744964181226146 0.85173429189048 GO:0031072 heat shock protein binding 2/376 131/18639 0.0152671755725191 0.756821503979211 0.744964181226146 0.85173429189048 GO:0005179 hormone activity 2/376 132/18639 0.0151515151515152 0.751088007736944 0.748741147312785 0.852509229468018 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/376 132/18639 0.0151515151515152 0.751088007736944 0.748741147312785 0.852509229468018 GO:0030145 manganese ion binding 1/376 68/18639 0.0147058823529412 0.728997183979975 0.750499578078683 0.852509229468018 GO:0032934 sterol binding 1/376 68/18639 0.0147058823529412 0.728997183979975 0.750499578078683 0.852509229468018 GO:0098960 postsynaptic neurotransmitter receptor activity 1/376 69/18639 0.0144927536231884 0.718432007400555 0.755551118579594 0.856860880844709 GO:0016782 transferase activity, transferring sulphur-containing groups 1/376 70/18639 0.0142857142857143 0.708168693009118 0.760500648973459 0.861082992869948 GO:0016779 nucleotidyltransferase activity 2/376 136/18639 0.0147058823529412 0.728997183979975 0.763372216122008 0.861555137809727 GO:0044325 transmembrane transporter binding 2/376 136/18639 0.0147058823529412 0.728997183979975 0.763372216122008 0.861555137809727 GO:0016922 nuclear receptor binding 2/376 137/18639 0.0145985401459854 0.723676036651654 0.766912793091968 0.864161766854834 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 1/376 73/18639 0.0136986301369863 0.679065870008744 0.774757519925784 0.871149747379972 GO:0003678 DNA helicase activity 1/376 74/18639 0.0135135135135135 0.669889304197815 0.779319147228806 0.871149747379972 GO:0003684 damaged DNA binding 1/376 74/18639 0.0135135135135135 0.669889304197815 0.779319147228806 0.871149747379972 GO:0031491 nucleosome binding 1/376 74/18639 0.0135135135135135 0.669889304197815 0.779319147228806 0.871149747379972 GO:0035064 methylated histone binding 1/376 74/18639 0.0135135135135135 0.669889304197815 0.779319147228806 0.871149747379972 GO:0017022 myosin binding 1/376 76/18639 0.0131578947368421 0.652260638297872 0.788167833137179 0.878244156924285 GO:0140034 methylation-dependent protein binding 1/376 76/18639 0.0131578947368421 0.652260638297872 0.788167833137179 0.878244156924285 GO:0015085 calcium ion transmembrane transporter activity 2/376 147/18639 0.0136054421768707 0.674446374294399 0.799853682568788 0.887121739782977 GO:0030971 receptor tyrosine kinase binding 1/376 81/18639 0.0123456790123457 0.611997635933806 0.808771956497301 0.887121739782977 GO:0033192 calmodulin-dependent protein phosphatase activity 1/376 81/18639 0.0123456790123457 0.611997635933806 0.808771956497301 0.887121739782977 GO:0140791 histone H2AXS140 phosphatase activity 1/376 81/18639 0.0123456790123457 0.611997635933806 0.808771956497301 0.887121739782977 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 1/376 81/18639 0.0123456790123457 0.611997635933806 0.808771956497301 0.887121739782977 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 1/376 81/18639 0.0123456790123457 0.611997635933806 0.808771956497301 0.887121739782977 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 1/376 81/18639 0.0123456790123457 0.611997635933806 0.808771956497301 0.887121739782977 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 1/376 81/18639 0.0123456790123457 0.611997635933806 0.808771956497301 0.887121739782977 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 1/376 81/18639 0.0123456790123457 0.611997635933806 0.808771956497301 0.887121739782977 GO:1990439 MAP kinase serine/threonine phosphatase activity 1/376 81/18639 0.0123456790123457 0.611997635933806 0.808771956497301 0.887121739782977 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 1/376 82/18639 0.0121951219512195 0.604534250129735 0.812646390399501 0.888594651184501 GO:0033549 MAP kinase phosphatase activity 1/376 82/18639 0.0121951219512195 0.604534250129735 0.812646390399501 0.888594651184501 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 1/376 83/18639 0.0120481927710843 0.597250704947449 0.816442529711339 0.889882056628184 GO:0003774 cytoskeletal motor activity 2/376 153/18639 0.0130718954248366 0.647997496871089 0.817581232825504 0.889882056628184 GO:0004527 exonuclease activity 1/376 84/18639 0.0119047619047619 0.590140577507599 0.820161952476404 0.889882056628184 GO:0004860 protein kinase inhibitor activity 1/376 84/18639 0.0119047619047619 0.590140577507599 0.820161952476404 0.889882056628184 GO:0017018 myosin phosphatase activity 1/376 84/18639 0.0119047619047619 0.590140577507599 0.820161952476404 0.889882056628184 GO:0050660 flavin adenine dinucleotide binding 1/376 86/18639 0.0116279069767442 0.576416378030678 0.827376802564276 0.896324869444632 GO:0140658 ATP-dependent chromatin remodeler activity 2/376 158/18639 0.0126582278481013 0.627491246970105 0.83126839773006 0.899153182136367 GO:0003727 single-stranded RNA binding 1/376 89/18639 0.0112359550561798 0.556986612479082 0.837661364316553 0.904674273461878 GO:0019210 kinase inhibitor activity 1/376 90/18639 0.0111111111111111 0.550797872340426 0.840951894074881 0.906832918034664 GO:0043178 alcohol binding 1/376 92/18639 0.0108695652173913 0.538824005550416 0.847334723780663 0.912314380512309 GO:0016887 ATP hydrolysis activity 6/376 417/18639 0.0143884892086331 0.713263431807745 0.849348973110553 0.913082663282708 GO:0016874 ligase activity 2/376 167/18639 0.0119760479041916 0.593674353420818 0.85359306038985 0.916242092345068 GO:0043021 ribonucleoprotein complex binding 2/376 177/18639 0.0112994350282486 0.560133429498738 0.875219289681911 0.938021284514048 GO:0042393 histone binding 3/376 247/18639 0.0121457489878543 0.60208674304419 0.878125330424457 0.939701192009099 GO:0022836 gated channel activity 4/376 318/18639 0.0125786163522013 0.623544761140104 0.886740735341324 0.947091060111586 GO:0019888 protein phosphatase regulator activity 1/376 107/18639 0.00934579439252336 0.463287930005965 0.887729227284079 0.947091060111586 GO:0004842 ubiquitin-protein transferase activity 6/376 449/18639 0.0133630289532294 0.662429512391603 0.893077785037844 0.951351449311937 GO:0043022 ribosome binding 1/376 112/18639 0.00892857142857143 0.442605433130699 0.898666913636731 0.955854808140886 GO:0019208 phosphatase regulator activity 1/376 117/18639 0.00854700854700855 0.423690671031097 0.908541580904332 0.964895899840909 GO:0005261 monoatomic cation channel activity 4/376 341/18639 0.0117302052785924 0.58148748986086 0.915853353345816 0.970768077679067 GO:0008528 G protein-coupled peptide receptor activity 1/376 122/18639 0.00819672131147541 0.406326299267527 0.917456293905232 0.970768077679067 GO:0005126 cytokine receptor binding 3/376 275/18639 0.0109090909090909 0.5407833655706 0.918219378317522 0.970768077679067 GO:0019787 ubiquitin-like protein transferase activity 6/376 479/18639 0.0125260960334029 0.620941233953716 0.923786057232931 0.974014502880904 GO:0001653 peptide receptor activity 1/376 128/18639 0.0078125 0.387279753989362 0.92701724531111 0.974014502880904 GO:0031490 chromatin DNA binding 1/376 128/18639 0.0078125 0.387279753989362 0.92701724531111 0.974014502880904 GO:0008094 ATP-dependent activity, acting on DNA 2/376 210/18639 0.00952380952380952 0.472112462006079 0.927380934798777 0.974014502880904 GO:0061630 ubiquitin protein ligase activity 4/376 353/18639 0.0113314447592068 0.561720209752275 0.928227496335221 0.974014502880904 GO:0016755 aminoacyltransferase activity 6/376 496/18639 0.0120967741935484 0.599658973919012 0.937516389327357 0.982293291504186 GO:0061659 ubiquitin-like protein ligase activity 4/376 372/18639 0.010752688172043 0.533030199039122 0.944498727076446 0.985811750703532 GO:0005085 guanyl-nucleotide exchange factor activity 2/376 230/18639 0.00869565217391304 0.431059204440333 0.948152119770512 0.985811750703532 GO:0015631 tubulin binding 4/376 385/18639 0.0103896103896104 0.515031776733904 0.95361365258855 0.985811750703532 GO:0000510 H3-H4 histone complex chaperone activity 1/376 151/18639 0.00662251655629139 0.328290122587009 0.954489280450861 0.985811750703532 GO:0140584 chromatin extrusion motor activity 1/376 151/18639 0.00662251655629139 0.328290122587009 0.954489280450861 0.985811750703532 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 1/376 151/18639 0.00662251655629139 0.328290122587009 0.954489280450861 0.985811750703532 GO:0140849 ATP-dependent H2AZ histone chaperone activity 1/376 151/18639 0.00662251655629139 0.328290122587009 0.954489280450861 0.985811750703532 GO:0051020 GTPase binding 3/376 315/18639 0.00952380952380952 0.472112462006079 0.954907256780743 0.985811750703532 GO:0015616 DNA translocase activity 1/376 152/18639 0.00657894736842105 0.326130319148936 0.955414855448183 0.985811750703532 GO:0140674 ATP-dependent histone chaperone activity 1/376 152/18639 0.00657894736842105 0.326130319148936 0.955414855448183 0.985811750703532 GO:0061775 cohesin loader activity 1/376 153/18639 0.0065359477124183 0.323998748435544 0.956321655597016 0.985811750703532 GO:0003689 DNA clamp loader activity 1/376 160/18639 0.00625 0.309823803191489 0.962174521191935 0.990390782810466 GO:0140713 histone chaperone activity 1/376 164/18639 0.00609756097560976 0.302267125064868 0.965160665640836 0.992009937452221 GO:0140097 catalytic activity, acting on DNA 3/376 336/18639 0.00892857142857143 0.442605433130699 0.967347553138419 0.992804067694694 GO:0005244 voltage-gated monoatomic ion channel activity 1/376 173/18639 0.00578034682080925 0.286542245726233 0.971047674057559 0.993442137590451 GO:0003823 antigen binding 1/376 174/18639 0.00574712643678161 0.284895451210565 0.971637193961943 0.993442137590451 GO:0022832 voltage-gated channel activity 1/376 175/18639 0.00571428571428571 0.283267477203647 0.972214741488091 0.993442137590451 GO:0008017 microtubule binding 2/376 276/18639 0.0072463768115942 0.359216003700278 0.976589387602311 0.993453191616693 GO:0015276 ligand-gated monoatomic ion channel activity 1/376 186/18639 0.00537634408602151 0.266515099519561 0.977843565350735 0.993453191616693 GO:0022834 ligand-gated channel activity 1/376 188/18639 0.00531914893617021 0.263679832503395 0.978737313338119 0.993453191616693 GO:0140597 protein carrier chaperone 1/376 188/18639 0.00531914893617021 0.263679832503395 0.978737313338119 0.993453191616693 GO:0031267 small GTPase binding 2/376 283/18639 0.00706713780918728 0.350330802195324 0.979301436750359 0.993453191616693 GO:0003714 transcription corepressor activity 1/376 204/18639 0.00490196078431373 0.242999061326658 0.984706964263521 0.996742190213052 GO:0004518 nuclease activity 1/376 209/18639 0.00478468899521531 0.237185686653772 0.986204368733806 0.996742190213052 GO:0019001 guanyl nucleotide binding 3/376 400/18639 0.0075 0.371788563829787 0.988223026194137 0.996742190213052 GO:0032561 guanyl ribonucleotide binding 3/376 400/18639 0.0075 0.371788563829787 0.988223026194137 0.996742190213052 GO:0003924 GTPase activity 2/376 331/18639 0.00604229607250755 0.299527543870926 0.991213920630082 0.998324493948806 GO:0140104 molecular carrier activity 1/376 249/18639 0.00401606425702811 0.199083568315816 0.993956586032084 0.999028136060986 GO:0003713 transcription coactivator activity 1/376 256/18639 0.00390625 0.193639876994681 0.994770369626595 0.999028136060986 GO:0005525 GTP binding 2/376 378/18639 0.00529100529100529 0.262284701114488 0.996271744892158 0.999028136060986 GO:0003712 transcription coregulator activity 3/376 495/18639 0.00606060606060606 0.300435203094778 0.99760501905805 0.999028136060986 GO:0140098 catalytic activity, acting on RNA 1/376 387/18639 0.00258397932816537 0.128092528451262 0.999654440884965 0.999654440884965