ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003712	transcription coregulator activity	120/1898	495/18639	0.242424242424242	2.38068780534534	4.90981514889156e-20	6.06853152402997e-17
GO:0003714	transcription corepressor activity	59/1898	204/18639	0.28921568627451	2.84019556189177	5.33897136832569e-14	3.29948430562528e-11
GO:0045296	cadherin binding	67/1898	334/18639	0.20059880239521	1.96994788084526	4.22655815778425e-08	1.74134196100711e-05
GO:0003713	transcription coactivator activity	54/1898	256/18639	0.2109375	2.07147737750263	1.57479490193942e-07	3.92369280079563e-05
GO:0008094	ATP-dependent activity, acting on DNA	47/1898	210/18639	0.223809523809524	2.19788499172061	1.58725436925389e-07	3.92369280079563e-05
GO:0140597	protein carrier chaperone	43/1898	188/18639	0.228723404255319	2.24614095464431	2.79287434662477e-07	5.75332115404702e-05
GO:0036121	double-stranded DNA helicase activity	18/1898	48/18639	0.375	3.68262644889357	4.67360405345339e-07	8.25224944295484e-05
GO:0042393	histone binding	51/1898	247/18639	0.206477732793522	2.02768095971468	6.8439842255151e-07	0.000105739556284208
GO:0140104	molecular carrier activity	51/1898	249/18639	0.204819277108434	2.01139436566075	8.83089923584927e-07	0.000121277682838997
GO:0140658	ATP-dependent chromatin remodeler activity	37/1898	158/18639	0.234177215189873	2.29969921703059	1.00846302512044e-06	0.0001215154141354
GO:0008137	NADH dehydrogenase (ubiquinone) activity	16/1898	41/18639	0.390243902439024	3.83232671104372	1.08144786042832e-06	0.0001215154141354
GO:0061775	cohesin loader activity	36/1898	153/18639	0.235294117647059	2.31066757577636	1.24543918418381e-06	0.000124873389745611
GO:0051020	GTPase binding	60/1898	315/18639	0.19047619047619	1.87054041848562	1.31339325784219e-06	0.000124873389745611
GO:0004386	helicase activity	36/1898	155/18639	0.232258064516129	2.28085251028247	1.72760985158915e-06	0.0001270922525132
GO:0061749	forked DNA-dependent helicase activity	17/1898	47/18639	0.361702127659574	3.55203685850728	1.75246262904736e-06	0.0001270922525132
GO:1990518	single-stranded 3'-5' DNA helicase activity	17/1898	47/18639	0.361702127659574	3.55203685850728	1.75246262904736e-06	0.0001270922525132
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	21/1898	68/18639	0.308823529411765	3.03275119320647	2.18878301649582e-06	0.0001270922525132
GO:0009378	four-way junction helicase activity	17/1898	48/18639	0.354166666666667	3.47803609062171	2.45719610656137e-06	0.0001270922525132
GO:0043138	3'-5' DNA helicase activity	17/1898	48/18639	0.354166666666667	3.47803609062171	2.45719610656137e-06	0.0001270922525132
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	19/1898	58/18639	0.327586206896552	3.21700701282657	2.46820077201001e-06	0.0001270922525132
GO:0000510	H3-H4 histone complex chaperone activity	35/1898	151/18639	0.231788079470199	2.27623709865386	2.51409973821533e-06	0.0001270922525132
GO:0140584	chromatin extrusion motor activity	35/1898	151/18639	0.231788079470199	2.27623709865386	2.51409973821533e-06	0.0001270922525132
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	35/1898	151/18639	0.231788079470199	2.27623709865386	2.51409973821533e-06	0.0001270922525132
GO:0140849	ATP-dependent H2AZ histone chaperone activity	35/1898	151/18639	0.231788079470199	2.27623709865386	2.51409973821533e-06	0.0001270922525132
GO:0003678	DNA helicase activity	22/1898	74/18639	0.297297297297297	2.91955970723094	2.5706361754288e-06	0.0001270922525132
GO:0015616	DNA translocase activity	35/1898	152/18639	0.230263157894737	2.26126185458377	2.95078404406193e-06	0.000135080336239279
GO:0140674	ATP-dependent histone chaperone activity	35/1898	152/18639	0.230263157894737	2.26126185458377	2.95078404406193e-06	0.000135080336239279
GO:0003954	NADH dehydrogenase activity	16/1898	44/18639	0.363636363636364	3.57103170801801	3.24919493409624e-06	0.000143428747805106
GO:0003689	DNA clamp loader activity	36/1898	160/18639	0.225	2.20957586933614	3.78735698638205e-06	0.000161419766729938
GO:0031267	small GTPase binding	54/1898	283/18639	0.190812720848057	1.8738452602144	4.13747799549604e-06	0.000170464093414437
GO:0022853	active monoatomic ion transmembrane transporter activity	29/1898	118/18639	0.245762711864407	2.4134727009698	5.26341514223793e-06	0.000209857455348583
GO:0140097	catalytic activity, acting on DNA	61/1898	336/18639	0.181547619047619	1.78285883636911	5.44198420426798e-06	0.00021014406563835
GO:0016922	nuclear receptor binding	32/1898	137/18639	0.233576642335766	2.29380138909186	5.61064252917925e-06	0.00021014406563835
GO:0022804	active transmembrane transporter activity	77/1898	457/18639	0.168490153172867	1.65463011854007	6.33075608425615e-06	0.000230141603533547
GO:0140713	histone chaperone activity	36/1898	164/18639	0.219512195121951	2.15568377496209	6.87058040601534e-06	0.000242629639480999
GO:0046332	SMAD binding	22/1898	79/18639	0.278481012658228	2.73477744727961	8.38539414363894e-06	0.000287898532264937
GO:0009055	electron transfer activity	28/1898	116/18639	0.241379310344828	2.37042621997747	1.09580840029977e-05	0.000366059238586625
GO:0140297	DNA-binding transcription factor binding	80/1898	488/18639	0.163934426229508	1.60989134377861	1.19166639041567e-05	0.000387605173303622
GO:0017116	single-stranded DNA helicase activity	17/1898	58/18639	0.293103448275862	2.87837469568693	4.25058270460866e-05	0.00134123694263804
GO:0001618	virus receptor activity	21/1898	81/18639	0.259259259259259	2.54601334738321	4.34057262989658e-05	0.00134123694263804
GO:0140034	methylation-dependent protein binding	20/1898	76/18639	0.263157894736842	2.58429926238145	5.20374296788658e-05	0.00151812156097475
GO:0016651	oxidoreductase activity, acting on NAD(P)H	22/1898	88/18639	0.25	2.45508429926238	5.26479755223925e-05	0.00151812156097475
GO:0140272	exogenous protein binding	21/1898	82/18639	0.25609756097561	2.51496440412244	5.28149086746878e-05	0.00151812156097475
GO:0015399	primary active transmembrane transporter activity	34/1898	166/18639	0.204819277108434	2.01139436566075	5.55140425165542e-05	0.00155943992160139
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	59/1898	349/18639	0.169054441260745	1.66017161783932	6.6933889118597e-05	0.00183845082112413
GO:0043236	laminin binding	11/1898	29/18639	0.379310344827586	3.72495548853603	7.20091751264412e-05	0.00193485522731046
GO:0050840	extracellular matrix binding	18/1898	67/18639	0.26865671641791	2.63829954547599	9.0818964108112e-05	0.00238834552420482
GO:0016887	ATP hydrolysis activity	67/1898	417/18639	0.160671462829736	1.57784794293122	0.000110222387267276	0.00283822647213236
GO:0140030	modification-dependent protein binding	34/1898	173/18639	0.196531791907514	1.93000846647216	0.000130487234843185	0.00329147392379952
GO:0004197	cysteine-type endopeptidase activity	21/1898	88/18639	0.238636363636364	2.34348955838682	0.000157860871807935	0.00390232075109215
GO:0005096	GTPase activator activity	47/1898	271/18639	0.173431734317343	1.70315811166542	0.00019263156087205	0.00466848253407557
GO:0030695	GTPase regulator activity	75/1898	489/18639	0.153374233128834	1.50618668666404	0.00020042088874768	0.00476385035561793
GO:0060589	nucleoside-triphosphatase regulator activity	75/1898	490/18639	0.153061224489796	1.50311283628309	0.000213615918713988	0.00498168444397149
GO:0015078	proton transmembrane transporter activity	35/1898	185/18639	0.189189189189189	1.85790163187423	0.000227829174955936	0.00521475667121364
GO:0042162	telomeric DNA binding	12/1898	38/18639	0.315789473684211	3.10115911485775	0.000259830802177553	0.0058391067543901
GO:0046966	nuclear thyroid hormone receptor binding	10/1898	28/18639	0.357142857142857	3.50726328466054	0.000273986584172346	0.00604727532208963
GO:0019787	ubiquitin-like protein transferase activity	73/1898	479/18639	0.152400835073069	1.49662758952947	0.000293667652418043	0.00636795119980179
GO:0005041	low-density lipoprotein particle receptor activity	7/1898	15/18639	0.466666666666667	4.58282402528978	0.000345199683693586	0.00733783760121369
GO:0035064	methylated histone binding	18/1898	74/18639	0.243243243243243	2.38873066955259	0.000353161879644839	0.00733783760121369
GO:1990841	promoter-specific chromatin binding	17/1898	68/18639	0.25	2.45508429926238	0.000361186936085587	0.00733783760121369
GO:0140033	acetylation-dependent protein binding	9/1898	24/18639	0.375	3.68262644889357	0.000364129567271164	0.00733783760121369
GO:0005178	integrin binding	31/1898	161/18639	0.192546583850932	1.89087237955612	0.00036807923242334	0.00733783760121369
GO:0015923	mannosidase activity	7/1898	16/18639	0.4375	4.29639752370917	0.000559884073348828	0.010984392296177
GO:0008234	cysteine-type peptidase activity	34/1898	187/18639	0.181818181818182	1.785515854009	0.000591441303331859	0.0114222101705965
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	15/1898	60/18639	0.25	2.45508429926238	0.000786600334296626	0.0149575078952405
GO:0016791	phosphatase activity	45/1898	273/18639	0.164835164835165	1.61873690061256	0.000805086356715883	0.0149717678848207
GO:0016755	aminoacyltransferase activity	73/1898	496/18639	0.147177419354839	1.44533188585608	0.000811576414468437	0.0149717678848207
GO:0004842	ubiquitin-protein transferase activity	67/1898	449/18639	0.149220489977728	1.46539552829024	0.000904954151495302	0.0164488725183558
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	8/1898	22/18639	0.363636363636364	3.57103170801801	0.00098282452959917	0.0173538731226368
GO:0046972	histone H4K16 acetyltransferase activity	8/1898	22/18639	0.363636363636364	3.57103170801801	0.00098282452959917	0.0173538731226368
GO:0017154	semaphorin receptor activity	6/1898	13/18639	0.461538461538462	4.53246332171517	0.00100830167336505	0.0175529699757635
GO:0042578	phosphoric ester hydrolase activity	56/1898	363/18639	0.154269972451791	1.51498314885613	0.0010570006315129	0.0181451775076382
GO:0061659	ubiquitin-like protein ligase activity	57/1898	372/18639	0.153225806451613	1.50472908664469	0.00112908515627396	0.0191171130569125
GO:0140416	transcription regulator inhibitor activity	10/1898	33/18639	0.303030303030303	2.97585975668167	0.0012030857371258	0.0200947833930741
GO:0030228	lipoprotein particle receptor activity	7/1898	18/18639	0.388888888888889	3.81902002107482	0.00129701961969177	0.0210936348676188
GO:0070064	proline-rich region binding	7/1898	18/18639	0.388888888888889	3.81902002107482	0.00129701961969177	0.0210936348676188
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	19/1898	89/18639	0.213483146067416	2.096476480269	0.00136932013249401	0.0214912767253203
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	19/1898	89/18639	0.213483146067416	2.096476480269	0.00136932013249401	0.0214912767253203
GO:0070577	lysine-acetylated histone binding	8/1898	23/18639	0.347826086956522	3.41576945984331	0.00137363338292905	0.0214912767253203
GO:0004721	phosphoprotein phosphatase activity	31/1898	175/18639	0.177142857142857	1.73960258919163	0.00155791114707137	0.0240061706429737
GO:0140793	histone H2AXY142 phosphatase activity	19/1898	90/18639	0.211111111111111	2.0731822971549	0.0015732199207774	0.0240061706429737
GO:0003779	actin binding	65/1898	443/18639	0.146726862302483	1.44090726367544	0.0016436600771223	0.0247751689673556
GO:0015924	mannosyl-oligosaccharide mannosidase activity	5/1898	10/18639	0.5	4.91016859852476	0.00176885851629873	0.026027489596967
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	5/1898	10/18639	0.5	4.91016859852476	0.00176885851629873	0.026027489596967
GO:0004725	protein tyrosine phosphatase activity	20/1898	98/18639	0.204081632653061	2.00415044837745	0.00185140402382046	0.0268006798360036
GO:0043998	histone H2A acetyltransferase activity	8/1898	24/18639	0.333333333333333	3.27344573234984	0.00187838529075799	0.0268006798360036
GO:0038024	cargo receptor activity	15/1898	65/18639	0.230769230769231	2.26623166085758	0.00188645561952452	0.0268006798360036
GO:0010485	histone H4 acetyltransferase activity	10/1898	35/18639	0.285714285714286	2.80581062772844	0.00197560256270507	0.0277482359943576
GO:0051087	protein-folding chaperone binding	25/1898	134/18639	0.186567164179104	1.83215246213611	0.00205351911078141	0.0285185350665822
GO:0140938	histone H3 methyltransferase activity	12/1898	47/18639	0.25531914893617	2.5073201354169	0.00211407720273041	0.0290333269174976
GO:0043995	histone H4K5 acetyltransferase activity	9/1898	30/18639	0.3	2.94610115911486	0.00227021742557259	0.0301719219140616
GO:0043996	histone H4K8 acetyltransferase activity	9/1898	30/18639	0.3	2.94610115911486	0.00227021742557259	0.0301719219140616
GO:0043997	histone H4K12 acetyltransferase activity	9/1898	30/18639	0.3	2.94610115911486	0.00227021742557259	0.0301719219140616
GO:0051213	dioxygenase activity	19/1898	93/18639	0.204301075268817	2.00630544885958	0.00234559295690282	0.0308420520716157
GO:0000774	adenyl-nucleotide exchange factor activity	6/1898	15/18639	0.4	3.92813487881981	0.00245845659328091	0.0316526286384917
GO:0004559	alpha-mannosidase activity	6/1898	15/18639	0.4	3.92813487881981	0.00245845659328091	0.0316526286384917
GO:0042974	nuclear retinoic acid receptor binding	8/1898	25/18639	0.32	3.14250790305585	0.00251862613322386	0.0319281056357935
GO:0044325	transmembrane transporter binding	25/1898	136/18639	0.183823529411765	1.80520904357528	0.00253151646626842	0.0319281056357935
GO:0140693	molecular condensate scaffold activity	12/1898	48/18639	0.25	2.45508429926238	0.00256199038354589	0.0319860617582093
GO:0000339	RNA cap binding	7/1898	20/18639	0.35	3.43711801896733	0.00263284793789666	0.0325420005124027
GO:0004843	cysteine-type deubiquitinase activity	21/1898	108/18639	0.194444444444444	1.90951001053741	0.00269403506917222	0.0329685875791769
GO:0008432	JUN kinase binding	5/1898	11/18639	0.454545454545455	4.46378963502251	0.00297207182795845	0.035321930570737
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	5/1898	11/18639	0.454545454545455	4.46378963502251	0.00297207182795845	0.035321930570737
GO:0034056	estrogen response element binding	5/1898	11/18639	0.454545454545455	4.46378963502251	0.00297207182795845	0.035321930570737
GO:0070412	R-SMAD binding	8/1898	26/18639	0.307692307692308	3.02164221447678	0.0033175609141981	0.0390524313328462
GO:0002039	p53 binding	15/1898	69/18639	0.217391304347826	2.13485591240207	0.00350052260358634	0.0408174145097427
GO:0140312	cargo adaptor activity	7/1898	21/18639	0.333333333333333	3.27344573234984	0.00360614375311331	0.0416560156901687
GO:0098631	cell adhesion mediator activity	16/1898	76/18639	0.210526315789474	2.06743940990516	0.00366733887570511	0.0419706560219585
GO:0030165	PDZ domain binding	17/1898	83/18639	0.204819277108434	2.01139436566075	0.00377524632589001	0.0428092152183491
GO:0015932	nucleobase-containing compound transmembrane transporter activity	13/1898	57/18639	0.228070175438596	2.23972602739726	0.00411529004912043	0.0462408954610259
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	18/1898	91/18639	0.197802197802198	1.94248428073507	0.00433397530134768	0.0477625936557679
GO:0000340	RNA 7-methylguanosine cap binding	5/1898	12/18639	0.416666666666667	4.0918071654373	0.00467069389057449	0.0477625936557679
GO:0031543	peptidyl-proline dioxygenase activity	5/1898	12/18639	0.416666666666667	4.0918071654373	0.00467069389057449	0.0477625936557679
GO:0032931	histone H3K56 acetyltransferase activity	7/1898	22/18639	0.318181818181818	3.12465274451576	0.00483035939075322	0.0477625936557679
GO:0043992	histone H3K9 acetyltransferase activity	7/1898	22/18639	0.318181818181818	3.12465274451576	0.00483035939075322	0.0477625936557679
GO:0043993	histone H3K18 acetyltransferase activity	7/1898	22/18639	0.318181818181818	3.12465274451576	0.00483035939075322	0.0477625936557679
GO:0043994	histone H3K23 acetyltransferase activity	7/1898	22/18639	0.318181818181818	3.12465274451576	0.00483035939075322	0.0477625936557679
GO:0043999	histone H2AK5 acetyltransferase activity	7/1898	22/18639	0.318181818181818	3.12465274451576	0.00483035939075322	0.0477625936557679
GO:0044012	histone H2AK9 acetyltransferase activity	7/1898	22/18639	0.318181818181818	3.12465274451576	0.00483035939075322	0.0477625936557679
GO:0044014	histone H2BK5 acetyltransferase activity	7/1898	22/18639	0.318181818181818	3.12465274451576	0.00483035939075322	0.0477625936557679
GO:0044015	histone H2BK12 acetyltransferase activity	7/1898	22/18639	0.318181818181818	3.12465274451576	0.00483035939075322	0.0477625936557679
GO:0044016	histone H3K4 acetyltransferase activity	7/1898	22/18639	0.318181818181818	3.12465274451576	0.00483035939075322	0.0477625936557679
GO:0044017	histone H3K27 acetyltransferase activity	7/1898	22/18639	0.318181818181818	3.12465274451576	0.00483035939075322	0.0477625936557679
GO:0044018	histone H3K36 acetyltransferase activity	7/1898	22/18639	0.318181818181818	3.12465274451576	0.00483035939075322	0.0477625936557679
GO:0140908	histone H3K122 acetyltransferase activity	7/1898	22/18639	0.318181818181818	3.12465274451576	0.00483035939075322	0.0477625936557679
GO:0003697	single-stranded DNA binding	22/1898	121/18639	0.181818181818182	1.785515854009	0.00507888423335242	0.0498214358128857
GO:0002020	protease binding	24/1898	136/18639	0.176470588235294	1.73300068183227	0.00522144472588777	0.0500287262108317
GO:0019838	growth factor binding	24/1898	136/18639	0.176470588235294	1.73300068183227	0.00522144472588777	0.0500287262108317
GO:0140789	histone phosphatase activity	24/1898	136/18639	0.176470588235294	1.73300068183227	0.00522144472588777	0.0500287262108317
GO:0036408	histone H3K14 acetyltransferase activity	8/1898	28/18639	0.285714285714286	2.80581062772844	0.00549122705387222	0.0522088972198928
GO:0070063	RNA polymerase binding	13/1898	59/18639	0.220338983050847	2.1638031112143	0.00561857701482289	0.0527869201241568
GO:0019902	phosphatase binding	31/1898	190/18639	0.163157894736842	1.6022655426765	0.0056374380715119	0.0527869201241568
GO:0090482	vitamin transmembrane transporter activity	9/1898	34/18639	0.264705882352941	2.5995010227484	0.00573513528902989	0.0530327559270934
GO:0001221	transcription coregulator binding	21/1898	115/18639	0.182608695652174	1.79327896641774	0.00579241266193982	0.0530327559270934
GO:0101005	deubiquitinase activity	21/1898	115/18639	0.182608695652174	1.79327896641774	0.00579241266193982	0.0530327559270934
GO:0016798	hydrolase activity, acting on glycosyl bonds	23/1898	130/18639	0.176923076923077	1.73744427332415	0.00597054657936529	0.0542617321477611
GO:1901505	carbohydrate derivative transmembrane transporter activity	12/1898	53/18639	0.226415094339623	2.22347257291687	0.00609424761258318	0.0549816791908964
GO:0005158	insulin receptor binding	7/1898	23/18639	0.304347826086957	2.9887982773629	0.00634267701917631	0.0563996316237548
GO:0044013	histone H2B acetyltransferase activity	7/1898	23/18639	0.304347826086957	2.9887982773629	0.00634267701917631	0.0563996316237548
GO:0061630	ubiquitin protein ligase activity	51/1898	353/18639	0.144475920679887	1.41880225793067	0.00661962371797709	0.0584418208244263
GO:0010484	histone H3 acetyltransferase activity	8/1898	29/18639	0.275862068965517	2.70905853711711	0.00691844108203069	0.0589306519085237
GO:0031994	insulin-like growth factor I binding	5/1898	13/18639	0.384615384615385	3.77705276809597	0.00695968902633038	0.0589306519085237
GO:0051011	microtubule minus-end binding	5/1898	13/18639	0.384615384615385	3.77705276809597	0.00695968902633038	0.0589306519085237
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	5/1898	13/18639	0.384615384615385	3.77705276809597	0.00695968902633038	0.0589306519085237
GO:0034185	apolipoprotein binding	6/1898	18/18639	0.333333333333333	3.27344573234984	0.00698079024387221	0.0589306519085237
GO:0035615	clathrin adaptor activity	6/1898	18/18639	0.333333333333333	3.27344573234984	0.00698079024387221	0.0589306519085237
GO:0015101	organic cation transmembrane transporter activity	16/1898	81/18639	0.197530864197531	1.93981969324435	0.00700874258135355	0.0589306519085237
GO:0030215	semaphorin receptor binding	7/1898	24/18639	0.291666666666667	2.86426501580611	0.00818091478970149	0.0667493003167235
GO:0050699	WW domain binding	7/1898	24/18639	0.291666666666667	2.86426501580611	0.00818091478970149	0.0667493003167235
GO:0070840	dynein complex binding	7/1898	24/18639	0.291666666666667	2.86426501580611	0.00818091478970149	0.0667493003167235
GO:0004402	histone acetyltransferase activity	10/1898	42/18639	0.238095238095238	2.33817552310703	0.00820865181888509	0.0667493003167235
GO:0048487	beta-tubulin binding	10/1898	42/18639	0.238095238095238	2.33817552310703	0.00820865181888509	0.0667493003167235
GO:0019783	ubiquitin-like protein peptidase activity	22/1898	127/18639	0.173228346456693	1.70116077429204	0.00904458819197622	0.0730660850018471
GO:0120227	acyl-CoA binding	6/1898	19/18639	0.315789473684211	3.10115911485775	0.00933752888317313	0.0749427642831298
GO:0005545	1-phosphatidylinositol binding	5/1898	14/18639	0.357142857142857	3.50726328466054	0.00992998635793282	0.0791836331509998
GO:0008013	beta-catenin binding	19/1898	106/18639	0.179245283018868	1.76024912022586	0.0102347361680888	0.0810906019471651
GO:0015291	secondary active transmembrane transporter activity	42/1898	287/18639	0.146341463414634	1.43712251664139	0.0103784568355187	0.0817055582719812
GO:0016878	acid-thiol ligase activity	8/1898	31/18639	0.258064516129032	2.53428056698052	0.0105894785794203	0.0828392121782499
GO:0019199	transmembrane receptor protein kinase activity	15/1898	78/18639	0.192307692307692	1.88852638404799	0.0113319964771552	0.0880902367658105
GO:1901981	phosphatidylinositol phosphate binding	29/1898	185/18639	0.156756756756757	1.53940420926722	0.0124364325289378	0.0960714412860448
GO:0008143	poly(A) binding	7/1898	26/18639	0.269230769230769	2.64393693766718	0.012985941467457	0.0996933146197317
GO:1901681	sulfur compound binding	40/1898	275/18639	0.145454545454545	1.4284126832072	0.0133572077428336	0.100681604729068
GO:0004090	carbonyl reductase (NADPH) activity	4/1898	10/18639	0.4	3.92813487881981	0.0136034207036847	0.100681604729068
GO:0005345	purine nucleobase transmembrane transporter activity	4/1898	10/18639	0.4	3.92813487881981	0.0136034207036847	0.100681604729068
GO:0008239	dipeptidyl-peptidase activity	4/1898	10/18639	0.4	3.92813487881981	0.0136034207036847	0.100681604729068
GO:0015643	toxic substance binding	4/1898	10/18639	0.4	3.92813487881981	0.0136034207036847	0.100681604729068
GO:0051864	histone H3K36 demethylase activity	4/1898	10/18639	0.4	3.92813487881981	0.0136034207036847	0.100681604729068
GO:0035091	phosphatidylinositol binding	41/1898	284/18639	0.144366197183099	1.41772473619377	0.013937479306904	0.102540026329365
GO:0015631	tubulin binding	53/1898	385/18639	0.137662337662338	1.35189057517825	0.0143646211193041	0.105057229014555
GO:0036002	pre-mRNA binding	12/1898	59/18639	0.203389830508475	1.99735671804397	0.014491611072116	0.105362536971385
GO:0008276	protein methyltransferase activity	17/1898	95/18639	0.178947368421053	1.75732349841939	0.0148443774084677	0.1072962016191
GO:0031625	ubiquitin protein ligase binding	43/1898	302/18639	0.142384105960265	1.39825993203023	0.0150556490358449	0.108190594234328
GO:0003684	damaged DNA binding	14/1898	74/18639	0.189189189189189	1.85790163187423	0.0162179150821249	0.115511560726524
GO:0016758	hexosyltransferase activity	30/1898	197/18639	0.152284263959391	1.49548282188571	0.0163705269454481	0.115511560726524
GO:0016407	acetyltransferase activity	17/1898	96/18639	0.177083333333333	1.73901804531085	0.0163797252761377	0.115511560726524
GO:0042054	histone methyltransferase activity	13/1898	67/18639	0.194029850746269	1.90543856062155	0.0164482481293432	0.115511560726524
GO:0019842	vitamin binding	24/1898	150/18639	0.16	1.57125395152792	0.0170916409102593	0.119351797542828
GO:0033218	amide binding	36/1898	247/18639	0.145748987854251	1.43130420685742	0.0176498498123276	0.12222524820842
GO:0015297	antiporter activity	22/1898	135/18639	0.162962962962963	1.60035124692659	0.0178834153020175	0.12222524820842
GO:0003725	double-stranded RNA binding	14/1898	75/18639	0.186666666666667	1.83312961011591	0.0181287520438452	0.12222524820842
GO:0061733	protein-lysine-acetyltransferase activity	10/1898	47/18639	0.212765957446809	2.08943344618075	0.0181359185051152	0.12222524820842
GO:0000062	fatty-acyl-CoA binding	5/1898	16/18639	0.3125	3.06885537407798	0.0182421835743582	0.12222524820842
GO:0005024	transforming growth factor beta receptor activity	5/1898	16/18639	0.3125	3.06885537407798	0.0182421835743582	0.12222524820842
GO:0034450	ubiquitin-ubiquitin ligase activity	5/1898	16/18639	0.3125	3.06885537407798	0.0182421835743582	0.12222524820842
GO:0005516	calmodulin binding	31/1898	207/18639	0.14975845410628	1.47067851743254	0.0185303246437402	0.12222524820842
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	11/1898	54/18639	0.203703703703704	2.00043905865824	0.0185908953585622	0.12222524820842
GO:0050661	NADP binding	11/1898	54/18639	0.203703703703704	2.00043905865824	0.0185908953585622	0.12222524820842
GO:0140463	chromatin-protein adaptor activity	11/1898	54/18639	0.203703703703704	2.00043905865824	0.0185908953585622	0.12222524820842
GO:0045499	chemorepellent activity	7/1898	28/18639	0.25	2.45508429926238	0.0195376999666472	0.124094886858506
GO:0097718	disordered domain specific binding	7/1898	28/18639	0.25	2.45508429926238	0.0195376999666472	0.124094886858506
GO:0141052	histone H3 demethylase activity	7/1898	28/18639	0.25	2.45508429926238	0.0195376999666472	0.124094886858506
GO:0019903	protein phosphatase binding	23/1898	144/18639	0.159722222222222	1.5685260800843	0.0196300781184598	0.124094886858506
GO:0002162	dystroglycan binding	4/1898	11/18639	0.363636363636364	3.57103170801801	0.0196784772040997	0.124094886858506
GO:0015205	nucleobase transmembrane transporter activity	4/1898	11/18639	0.363636363636364	3.57103170801801	0.0196784772040997	0.124094886858506
GO:0047676	arachidonate-CoA ligase activity	4/1898	11/18639	0.363636363636364	3.57103170801801	0.0196784772040997	0.124094886858506
GO:0097493	structural molecule activity conferring elasticity	4/1898	11/18639	0.363636363636364	3.57103170801801	0.0196784772040997	0.124094886858506
GO:0016877	ligase activity, forming carbon-sulfur bonds	9/1898	41/18639	0.219512195121951	2.15568377496209	0.0200749991912762	0.125952786804149
GO:0016279	protein-lysine N-methyltransferase activity	13/1898	69/18639	0.188405797101449	1.85020845741513	0.0207344427782098	0.129433188251855
GO:0051015	actin filament binding	31/1898	209/18639	0.148325358851675	1.45660503879682	0.0209706714300036	0.1301558767493
GO:0008194	UDP-glycosyltransferase activity	23/1898	145/18639	0.158620689655172	1.55770865884234	0.0211565830161127	0.1301558767493
GO:0098632	cell-cell adhesion mediator activity	11/1898	55/18639	0.2	1.96406743940991	0.0211661255878715	0.1301558767493
GO:0016757	glycosyltransferase activity	38/1898	267/18639	0.142322097378277	1.397650986846	0.0213795626888895	0.130817522195383
GO:0008017	microtubule binding	39/1898	276/18639	0.141304347826087	1.38765634306135	0.0221418876390842	0.134814645920729
GO:0016278	lysine N-methyltransferase activity	13/1898	70/18639	0.185714285714286	1.82377690802348	0.023166856290326	0.139706033468342
GO:0017124	SH3 domain binding	19/1898	115/18639	0.165217391304348	1.62249049342557	0.0231713081399758	0.139706033468342
GO:0106222	lncRNA binding	7/1898	29/18639	0.241379310344828	2.37042621997747	0.0235529187026616	0.140299858470133
GO:0032183	SUMO binding	5/1898	17/18639	0.294117647058824	2.88833446972045	0.0237238433820857	0.140299858470133
GO:0070403	NAD+ binding	5/1898	17/18639	0.294117647058824	2.88833446972045	0.0237238433820857	0.140299858470133
GO:1901567	fatty acid derivative binding	5/1898	17/18639	0.294117647058824	2.88833446972045	0.0237238433820857	0.140299858470133
GO:0016409	palmitoyltransferase activity	8/1898	36/18639	0.222222222222222	2.18229715489989	0.0257855698647586	0.151494609200498
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	33/1898	229/18639	0.14410480349345	1.41515776202024	0.025861943803645	0.151494609200498
GO:0019209	kinase activator activity	23/1898	148/18639	0.155405405405405	1.52613348332526	0.0262926916912322	0.153291353445108
GO:0044389	ubiquitin-like protein ligase binding	44/1898	322/18639	0.136645962732919	1.34190943065273	0.0267820562221945	0.153828159347008
GO:0008375	acetylglucosaminyltransferase activity	9/1898	43/18639	0.209302325581395	2.05541941333595	0.0269029552487826	0.153828159347008
GO:0048156	tau protein binding	9/1898	43/18639	0.209302325581395	2.05541941333595	0.0269029552487826	0.153828159347008
GO:0004300	enoyl-CoA hydratase activity	4/1898	12/18639	0.333333333333333	3.27344573234984	0.0271823688608623	0.153828159347008
GO:0005078	MAP-kinase scaffold activity	4/1898	12/18639	0.333333333333333	3.27344573234984	0.0271823688608623	0.153828159347008
GO:0017166	vinculin binding	4/1898	12/18639	0.333333333333333	3.27344573234984	0.0271823688608623	0.153828159347008
GO:0015605	organophosphate ester transmembrane transporter activity	10/1898	50/18639	0.2	1.96406743940991	0.0272559602726494	0.153828159347008
GO:0008106	alcohol dehydrogenase (NADP+) activity	7/1898	30/18639	0.233333333333333	2.29141201264489	0.028101157890044	0.157163036887305
GO:0032452	histone demethylase activity	7/1898	30/18639	0.233333333333333	2.29141201264489	0.028101157890044	0.157163036887305
GO:0050431	transforming growth factor beta binding	6/1898	24/18639	0.25	2.45508429926238	0.0298459524741718	0.166169357018362
GO:0000900	mRNA regulatory element binding translation repressor activity	5/1898	18/18639	0.277777777777778	2.72787144362487	0.0301634792044755	0.166437769181838
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	5/1898	18/18639	0.277777777777778	2.72787144362487	0.0301634792044755	0.166437769181838
GO:0019205	nucleobase-containing compound kinase activity	9/1898	44/18639	0.204545454545455	2.00870533576013	0.0308673502730352	0.169079254760358
GO:0016830	carbon-carbon lyase activity	10/1898	51/18639	0.196078431372549	1.92555631314697	0.0309157860645962	0.169079254760358
GO:0043539	protein serine/threonine kinase activator activity	13/1898	73/18639	0.178082191780822	1.74882717207731	0.0317312563958722	0.172774594296467
GO:0016829	lyase activity	29/1898	200/18639	0.145	1.42394889357218	0.0325305138820112	0.176349627886692
GO:0070325	lipoprotein particle receptor binding	7/1898	31/18639	0.225806451612903	2.21749549610796	0.0332087310223092	0.178460832798149
GO:0140457	protein demethylase activity	7/1898	31/18639	0.225806451612903	2.21749549610796	0.0332087310223092	0.178460832798149
GO:0031491	nucleosome binding	13/1898	74/18639	0.175675675675676	1.72519437245465	0.0350373783151953	0.187472725530656
GO:0005338	nucleotide-sugar transmembrane transporter activity	4/1898	13/18639	0.307692307692308	3.02164221447678	0.0361702265650987	0.189189518464438
GO:0046975	histone H3K36 methyltransferase activity	4/1898	13/18639	0.307692307692308	3.02164221447678	0.0361702265650987	0.189189518464438
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	4/1898	13/18639	0.307692307692308	3.02164221447678	0.0361702265650987	0.189189518464438
GO:0070123	transforming growth factor beta receptor activity, type III	4/1898	13/18639	0.307692307692308	3.02164221447678	0.0361702265650987	0.189189518464438
GO:0097157	pre-mRNA intronic binding	4/1898	13/18639	0.307692307692308	3.02164221447678	0.0361702265650987	0.189189518464438
GO:0008514	organic anion transmembrane transporter activity	37/1898	269/18639	0.137546468401487	1.35075269996592	0.0362766309676957	0.189189518464438
GO:0004674	protein serine/threonine kinase activity	56/1898	433/18639	0.12933025404157	1.2700667044683	0.0365783377079097	0.189961451289817
GO:0051082	unfolded protein binding	19/1898	121/18639	0.15702479338843	1.54203641937141	0.0370559201086937	0.191636473867554
GO:0005520	insulin-like growth factor binding	5/1898	19/18639	0.263157894736842	2.58429926238145	0.0376013186049406	0.19204640411449
GO:0042577	lipid phosphatase activity	5/1898	19/18639	0.263157894736842	2.58429926238145	0.0376013186049406	0.19204640411449
GO:0042800	histone H3K4 methyltransferase activity	5/1898	19/18639	0.263157894736842	2.58429926238145	0.0376013186049406	0.19204640411449
GO:0008378	galactosyltransferase activity	7/1898	32/18639	0.21875	2.14819876185458	0.0388985038116781	0.196238982494833
GO:0042910	xenobiotic transmembrane transporter activity	7/1898	32/18639	0.21875	2.14819876185458	0.0388985038116781	0.196238982494833
GO:0070717	poly-purine tract binding	7/1898	32/18639	0.21875	2.14819876185458	0.0388985038116781	0.196238982494833
GO:0034212	protein N-acetyltransferase activity	10/1898	53/18639	0.188679245283019	1.85289381076406	0.0392463878228141	0.197189168085359
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	19/1898	122/18639	0.155737704918033	1.52939677658968	0.0398624926257341	0.198557347541236
GO:0030276	clathrin binding	9/1898	46/18639	0.195652173913043	1.92137032116186	0.0399770015325945	0.198557347541236
GO:0016776	phosphotransferase activity, phosphate group as acceptor	8/1898	39/18639	0.205128205128205	2.01442814298452	0.0400006306939869	0.198557347541236
GO:0030295	protein kinase activator activity	21/1898	139/18639	0.151079136690647	1.4836480657413	0.0425912940430058	0.208728499818801
GO:0005160	transforming growth factor beta receptor binding	6/1898	26/18639	0.230769230769231	2.26623166085758	0.0428940444611452	0.208728499818801
GO:0050681	nuclear androgen receptor binding	6/1898	26/18639	0.230769230769231	2.26623166085758	0.0428940444611452	0.208728499818801
GO:0050750	low-density lipoprotein particle receptor binding	6/1898	26/18639	0.230769230769231	2.26623166085758	0.0428940444611452	0.208728499818801
GO:0070006	metalloaminopeptidase activity	6/1898	26/18639	0.230769230769231	2.26623166085758	0.0428940444611452	0.208728499818801
GO:0051287	NAD binding	10/1898	54/18639	0.185185185185185	1.81858096241658	0.0439408179283259	0.212983729252592
GO:0008080	N-acetyltransferase activity	12/1898	69/18639	0.173913043478261	1.70788472992166	0.0446845588545606	0.215742635719675
GO:0004177	aminopeptidase activity	8/1898	40/18639	0.2	1.96406743940991	0.0457068607977488	0.217658772803339
GO:0030331	nuclear estrogen receptor binding	8/1898	40/18639	0.2	1.96406743940991	0.0457068607977488	0.217658772803339
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	20/1898	132/18639	0.151515151515152	1.48792987834084	0.0457740537083705	0.217658772803339
GO:0031418	L-ascorbic acid binding	5/1898	20/18639	0.25	2.45508429926238	0.0460647702819189	0.217658772803339
GO:0015926	glucosidase activity	4/1898	14/18639	0.285714285714286	2.80581062772844	0.046666322647965	0.217658772803339
GO:0030983	mismatched DNA binding	4/1898	14/18639	0.285714285714286	2.80581062772844	0.046666322647965	0.217658772803339
GO:0032454	histone H3K9 demethylase activity	4/1898	14/18639	0.285714285714286	2.80581062772844	0.046666322647965	0.217658772803339
GO:0042813	Wnt receptor activity	4/1898	14/18639	0.285714285714286	2.80581062772844	0.046666322647965	0.217658772803339
GO:0061665	SUMO ligase activity	4/1898	14/18639	0.285714285714286	2.80581062772844	0.046666322647965	0.217658772803339
GO:0016405	CoA-ligase activity	6/1898	27/18639	0.222222222222222	2.18229715489989	0.050570605239057	0.234982210810055
GO:0050660	flavin adenine dinucleotide binding	14/1898	86/18639	0.162790697674419	1.59865954370574	0.0518216346682551	0.239376350637085
GO:0008376	acetylgalactosaminyltransferase activity	7/1898	34/18639	0.205882352941176	2.02183412880431	0.0520972801952879	0.239376350637085
GO:0016831	carboxy-lyase activity	7/1898	34/18639	0.205882352941176	2.02183412880431	0.0520972801952879	0.239376350637085
GO:0008238	exopeptidase activity	16/1898	102/18639	0.156862745098039	1.54044505051757	0.0528936965957012	0.242135588860321
GO:0005543	phospholipid binding	62/1898	497/18639	0.124748490945674	1.2250722459096	0.0538051327314672	0.245399055557541
GO:0051010	microtubule plus-end binding	5/1898	21/18639	0.238095238095238	2.33817552310703	0.0555684824005302	0.252509721496527
GO:0001222	transcription corepressor binding	9/1898	49/18639	0.183673469387755	1.80373540353971	0.0567883326125798	0.25616926682171
GO:0060590	ATPase regulator activity	9/1898	49/18639	0.183673469387755	1.80373540353971	0.0567883326125798	0.25616926682171
GO:0004129	cytochrome-c oxidase activity	4/1898	15/18639	0.266666666666667	2.61875658587987	0.0586665304325855	0.257831018817962
GO:0004467	long-chain fatty acid-CoA ligase activity	4/1898	15/18639	0.266666666666667	2.61875658587987	0.0586665304325855	0.257831018817962
GO:0042809	nuclear vitamin D receptor binding	4/1898	15/18639	0.266666666666667	2.61875658587987	0.0586665304325855	0.257831018817962
GO:0048531	beta-1,3-galactosyltransferase activity	4/1898	15/18639	0.266666666666667	2.61875658587987	0.0586665304325855	0.257831018817962
GO:0061578	K63-linked deubiquitinase activity	4/1898	15/18639	0.266666666666667	2.61875658587987	0.0586665304325855	0.257831018817962
GO:0120283	protein serine/threonine kinase binding	4/1898	15/18639	0.266666666666667	2.61875658587987	0.0586665304325855	0.257831018817962
GO:0005518	collagen binding	12/1898	72/18639	0.166666666666667	1.63672286617492	0.0589270976544859	0.257831018817962
GO:0019789	SUMO transferase activity	6/1898	28/18639	0.214285714285714	2.10435797079633	0.0590341248588052	0.257831018817962
GO:0046875	ephrin receptor binding	6/1898	28/18639	0.214285714285714	2.10435797079633	0.0590341248588052	0.257831018817962
GO:0031490	chromatin DNA binding	19/1898	128/18639	0.1484375	1.45770630268704	0.0600135051704141	0.261185536586732
GO:0004175	endopeptidase activity	51/1898	405/18639	0.125925925925926	1.23663505444327	0.0651688905652744	0.282627188556769
GO:0106310	protein serine kinase activity	46/1898	361/18639	0.127423822714681	1.25134490599523	0.0656130813498866	0.283558631288321
GO:0050321	tau-protein kinase activity	5/1898	22/18639	0.227272727272727	2.23189481751126	0.0661147004465048	0.284730905058815
GO:0000993	RNA polymerase II complex binding	7/1898	36/18639	0.194444444444444	1.90951001053741	0.0678025947511729	0.289979263364878
GO:0004033	aldo-keto reductase (NADPH) activity	7/1898	36/18639	0.194444444444444	1.90951001053741	0.0678025947511729	0.289979263364878
GO:0016417	S-acyltransferase activity	6/1898	29/18639	0.206896551724138	2.03179390283783	0.068290091682147	0.290056884258192
GO:0035250	UDP-galactosyltransferase activity	6/1898	29/18639	0.206896551724138	2.03179390283783	0.068290091682147	0.290056884258192
GO:0008235	metalloexopeptidase activity	11/1898	66/18639	0.166666666666667	1.63672286617492	0.0686011647320716	0.290380272633016
GO:0048029	monosaccharide binding	12/1898	74/18639	0.162162162162162	1.59248711303506	0.0699364000325951	0.295021810376408
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	13/1898	82/18639	0.158536585365854	1.55688272636151	0.0706612672821326	0.297065735920802
GO:0016675	oxidoreductase activity, acting on a heme group of donors	4/1898	16/18639	0.25	2.45508429926238	0.0721413127186612	0.299107565136194
GO:0005337	nucleoside transmembrane transporter activity	3/1898	10/18639	0.3	2.94610115911486	0.0733249128125137	0.299107565136194
GO:0005381	iron ion transmembrane transporter activity	3/1898	10/18639	0.3	2.94610115911486	0.0733249128125137	0.299107565136194
GO:0005522	profilin binding	3/1898	10/18639	0.3	2.94610115911486	0.0733249128125137	0.299107565136194
GO:0016783	sulfurtransferase activity	3/1898	10/18639	0.3	2.94610115911486	0.0733249128125137	0.299107565136194
GO:0031957	very long-chain fatty acid-CoA ligase activity	3/1898	10/18639	0.3	2.94610115911486	0.0733249128125137	0.299107565136194
GO:0045322	unmethylated CpG binding	3/1898	10/18639	0.3	2.94610115911486	0.0733249128125137	0.299107565136194
GO:0070097	delta-catenin binding	3/1898	10/18639	0.3	2.94610115911486	0.0733249128125137	0.299107565136194
GO:0140999	histone H3K4 trimethyltransferase activity	3/1898	10/18639	0.3	2.94610115911486	0.0733249128125137	0.299107565136194
GO:0001046	core promoter sequence-specific DNA binding	8/1898	44/18639	0.181818181818182	1.785515854009	0.07369633416644	0.299633779703026
GO:0044183	protein folding chaperone	12/1898	75/18639	0.16	1.57125395152792	0.0759085266223072	0.307616193131711
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	13/1898	83/18639	0.156626506024096	1.53812510315234	0.07634378762156	0.308369024510615
GO:0017134	fibroblast growth factor binding	5/1898	23/18639	0.217391304347826	2.13485591240207	0.0776938691669077	0.312800072606834
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	32/1898	243/18639	0.131687242798354	1.29321312882957	0.0782208243433165	0.313899152234867
GO:0001098	basal transcription machinery binding	10/1898	60/18639	0.166666666666667	1.63672286617492	0.0800669765395944	0.316901114961431
GO:0001099	basal RNA polymerase II transcription machinery binding	10/1898	60/18639	0.166666666666667	1.63672286617492	0.0800669765395944	0.316901114961431
GO:0004714	transmembrane receptor protein tyrosine kinase activity	10/1898	60/18639	0.166666666666667	1.63672286617492	0.0800669765395944	0.316901114961431
GO:0046915	transition metal ion transmembrane transporter activity	8/1898	45/18639	0.177777777777778	1.74583772391992	0.0820154339062924	0.316901114961431
GO:0140303	intramembrane lipid transporter activity	8/1898	45/18639	0.177777777777778	1.74583772391992	0.0820154339062924	0.316901114961431
GO:0051117	ATPase binding	13/1898	84/18639	0.154761904761905	1.51981409001957	0.0823119142637327	0.316901114961431
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	23/1898	167/18639	0.137724550898204	1.35250153013257	0.0830246324283787	0.316901114961431
GO:0004676	3-phosphoinositide-dependent protein kinase activity	32/1898	245/18639	0.130612244897959	1.28265628696157	0.0851223059605137	0.316901114961431
GO:0004711	ribosomal protein S6 kinase activity	32/1898	245/18639	0.130612244897959	1.28265628696157	0.0851223059605137	0.316901114961431
GO:0035175	histone H3S10 kinase activity	32/1898	245/18639	0.130612244897959	1.28265628696157	0.0851223059605137	0.316901114961431
GO:0035979	histone H2AXS139 kinase activity	32/1898	245/18639	0.130612244897959	1.28265628696157	0.0851223059605137	0.316901114961431
GO:0044022	histone H3S28 kinase activity	32/1898	245/18639	0.130612244897959	1.28265628696157	0.0851223059605137	0.316901114961431
GO:0044023	histone H4S1 kinase activity	32/1898	245/18639	0.130612244897959	1.28265628696157	0.0851223059605137	0.316901114961431
GO:0044024	histone H2AS1 kinase activity	32/1898	245/18639	0.130612244897959	1.28265628696157	0.0851223059605137	0.316901114961431
GO:0044025	histone H2BS14 kinase activity	32/1898	245/18639	0.130612244897959	1.28265628696157	0.0851223059605137	0.316901114961431
GO:0072354	histone H3T3 kinase activity	32/1898	245/18639	0.130612244897959	1.28265628696157	0.0851223059605137	0.316901114961431
GO:0072371	histone H2AS121 kinase activity	32/1898	245/18639	0.130612244897959	1.28265628696157	0.0851223059605137	0.316901114961431
GO:0072518	Rho-dependent protein serine/threonine kinase activity	32/1898	245/18639	0.130612244897959	1.28265628696157	0.0851223059605137	0.316901114961431
GO:0140823	histone H2BS36 kinase activity	32/1898	245/18639	0.130612244897959	1.28265628696157	0.0851223059605137	0.316901114961431
GO:0140855	histone H3S57 kinase activity	32/1898	245/18639	0.130612244897959	1.28265628696157	0.0851223059605137	0.316901114961431
GO:0140995	histone H2A kinase activity	32/1898	245/18639	0.130612244897959	1.28265628696157	0.0851223059605137	0.316901114961431
GO:0140997	histone H4 kinase activity	32/1898	245/18639	0.130612244897959	1.28265628696157	0.0851223059605137	0.316901114961431
GO:0140998	histone H2B kinase activity	32/1898	245/18639	0.130612244897959	1.28265628696157	0.0851223059605137	0.316901114961431
GO:1990244	histone H2AT120 kinase activity	32/1898	245/18639	0.130612244897959	1.28265628696157	0.0851223059605137	0.316901114961431
GO:0051018	protein kinase A binding	9/1898	53/18639	0.169811320754717	1.66760442968766	0.0854352062140487	0.31711085549719
GO:0042887	amide transmembrane transporter activity	7/1898	38/18639	0.184210526315789	1.80900948366702	0.0860534335490637	0.318284611097742
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	4/1898	17/18639	0.235294117647059	2.31066757577636	0.0870389955914537	0.318284611097742
GO:0019198	transmembrane receptor protein phosphatase activity	4/1898	17/18639	0.235294117647059	2.31066757577636	0.0870389955914537	0.318284611097742
GO:0032977	membrane insertase activity	4/1898	17/18639	0.235294117647059	2.31066757577636	0.0870389955914537	0.318284611097742
GO:0046965	nuclear retinoid X receptor binding	4/1898	17/18639	0.235294117647059	2.31066757577636	0.0870389955914537	0.318284611097742
GO:0016836	hydro-lyase activity	10/1898	61/18639	0.163934426229508	1.60989134377861	0.0874641096430464	0.318895691795886
GO:0004677	DNA-dependent protein kinase activity	32/1898	246/18639	0.130081300813008	1.27744223701457	0.0887234616371695	0.320383372142588
GO:0140857	histone H3T45 kinase activity	32/1898	246/18639	0.130081300813008	1.27744223701457	0.0887234616371695	0.320383372142588
GO:0003724	RNA helicase activity	12/1898	77/18639	0.155844155844156	1.53044216057915	0.0888007887888367	0.320383372142588
GO:0017147	Wnt-protein binding	6/1898	31/18639	0.193548387096774	1.90071042523539	0.0891681877160601	0.320383372142588
GO:0072349	modified amino acid transmembrane transporter activity	6/1898	31/18639	0.193548387096774	1.90071042523539	0.0891681877160601	0.320383372142588
GO:0015295	solute:proton symporter activity	5/1898	24/18639	0.208333333333333	2.04590358271865	0.090285426191312	0.321712298442247
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	8/1898	46/18639	0.173913043478261	1.70788472992166	0.0908656301954921	0.321712298442247
GO:0035402	histone H3T11 kinase activity	32/1898	247/18639	0.129554655870445	1.27227040609549	0.0924258331833586	0.321712298442247
GO:0035403	histone H3T6 kinase activity	32/1898	247/18639	0.129554655870445	1.27227040609549	0.0924258331833586	0.321712298442247
GO:0042826	histone deacetylase binding	18/1898	127/18639	0.141732283464567	1.39185881532985	0.0933649373177533	0.321712298442247
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	3/1898	11/18639	0.272727272727273	2.67827378101351	0.0934423261656688	0.321712298442247
GO:0008172	S-methyltransferase activity	3/1898	11/18639	0.272727272727273	2.67827378101351	0.0934423261656688	0.321712298442247
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	3/1898	11/18639	0.272727272727273	2.67827378101351	0.0934423261656688	0.321712298442247
GO:0019107	myristoyltransferase activity	3/1898	11/18639	0.272727272727273	2.67827378101351	0.0934423261656688	0.321712298442247
GO:0032050	clathrin heavy chain binding	3/1898	11/18639	0.272727272727273	2.67827378101351	0.0934423261656688	0.321712298442247
GO:0032404	mismatch repair complex binding	3/1898	11/18639	0.272727272727273	2.67827378101351	0.0934423261656688	0.321712298442247
GO:0032794	GTPase activating protein binding	3/1898	11/18639	0.272727272727273	2.67827378101351	0.0934423261656688	0.321712298442247
GO:0034713	type I transforming growth factor beta receptor binding	3/1898	11/18639	0.272727272727273	2.67827378101351	0.0934423261656688	0.321712298442247
GO:0048185	activin binding	3/1898	11/18639	0.272727272727273	2.67827378101351	0.0934423261656688	0.321712298442247
GO:0050998	nitric-oxide synthase binding	3/1898	11/18639	0.272727272727273	2.67827378101351	0.0934423261656688	0.321712298442247
GO:0016410	N-acyltransferase activity	14/1898	94/18639	0.148936170212766	1.46260341232653	0.0941296679350328	0.323178526576946
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	13/1898	86/18639	0.151162790697674	1.48446957629818	0.0951111396658139	0.325643680407052
GO:0031406	carboxylic acid binding	25/1898	187/18639	0.133689839572193	1.31287930441839	0.0956401599222114	0.326550380286888
GO:0004679	AMP-activated protein kinase activity	32/1898	248/18639	0.129032258064516	1.26714028349026	0.0962300213636481	0.327659246296058
GO:0004722	protein serine/threonine phosphatase activity	15/1898	103/18639	0.145631067961165	1.43014619374508	0.0989978587043729	0.336157564171992
GO:0071813	lipoprotein particle binding	6/1898	32/18639	0.1875	1.84131322444679	0.100768884001687	0.339374225139196
GO:0071814	protein-lipid complex binding	6/1898	32/18639	0.1875	1.84131322444679	0.100768884001687	0.339374225139196
GO:0140142	nucleocytoplasmic carrier activity	6/1898	32/18639	0.1875	1.84131322444679	0.100768884001687	0.339374225139196
GO:0008186	ATP-dependent activity, acting on RNA	12/1898	79/18639	0.151898734177215	1.49169678942524	0.102963552258148	0.339601591356782
GO:0017128	phospholipid scramblase activity	4/1898	18/18639	0.222222222222222	2.18229715489989	0.10328914313059	0.339601591356782
GO:0005507	copper ion binding	10/1898	63/18639	0.158730158730159	1.55878368207135	0.103452195892865	0.339601591356782
GO:1901682	sulfur compound transmembrane transporter activity	10/1898	63/18639	0.158730158730159	1.55878368207135	0.103452195892865	0.339601591356782
GO:0008139	nuclear localization sequence binding	5/1898	25/18639	0.2	1.96406743940991	0.103858739104259	0.339601591356782
GO:0015645	fatty acid ligase activity	5/1898	25/18639	0.2	1.96406743940991	0.103858739104259	0.339601591356782
GO:0015662	P-type ion transporter activity	5/1898	25/18639	0.2	1.96406743940991	0.103858739104259	0.339601591356782
GO:0019706	protein-cysteine S-palmitoyltransferase activity	5/1898	25/18639	0.2	1.96406743940991	0.103858739104259	0.339601591356782
GO:0019707	protein-cysteine S-acyltransferase activity	5/1898	25/18639	0.2	1.96406743940991	0.103858739104259	0.339601591356782
GO:0120515	fatty acid-CoA ligase activity	5/1898	25/18639	0.2	1.96406743940991	0.103858739104259	0.339601591356782
GO:0140358	P-type transmembrane transporter activity	5/1898	25/18639	0.2	1.96406743940991	0.103858739104259	0.339601591356782
GO:0015293	symporter activity	20/1898	146/18639	0.136986301369863	1.3452516708287	0.104670836549618	0.340885160554989
GO:0043177	organic acid binding	25/1898	189/18639	0.132275132275132	1.29898640172613	0.104802881076777	0.340885160554989
GO:0008201	heparin binding	23/1898	172/18639	0.133720930232558	1.31318462518686	0.1061710926015	0.342054251681681
GO:0015036	disulfide oxidoreductase activity	7/1898	40/18639	0.175	1.71855900948367	0.106822767920007	0.342054251681681
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	7/1898	40/18639	0.175	1.71855900948367	0.106822767920007	0.342054251681681
GO:0032451	demethylase activity	7/1898	40/18639	0.175	1.71855900948367	0.106822767920007	0.342054251681681
GO:0071949	FAD binding	7/1898	40/18639	0.175	1.71855900948367	0.106822767920007	0.342054251681681
GO:0140662	ATP-dependent protein folding chaperone	7/1898	40/18639	0.175	1.71855900948367	0.106822767920007	0.342054251681681
GO:0032266	phosphatidylinositol-3-phosphate binding	8/1898	48/18639	0.166666666666667	1.63672286617492	0.110141763302503	0.349686388461508
GO:0071889	14-3-3 protein binding	6/1898	33/18639	0.181818181818182	1.785515854009	0.113119832030517	0.349686388461508
GO:0003995	acyl-CoA dehydrogenase activity	3/1898	12/18639	0.25	2.45508429926238	0.115528978600604	0.349686388461508
GO:0005025	transforming growth factor beta receptor activity, type I	3/1898	12/18639	0.25	2.45508429926238	0.115528978600604	0.349686388461508
GO:0005026	transforming growth factor beta receptor activity, type II	3/1898	12/18639	0.25	2.45508429926238	0.115528978600604	0.349686388461508
GO:0005095	GTPase inhibitor activity	3/1898	12/18639	0.25	2.45508429926238	0.115528978600604	0.349686388461508
GO:0005247	voltage-gated chloride channel activity	3/1898	12/18639	0.25	2.45508429926238	0.115528978600604	0.349686388461508
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	3/1898	12/18639	0.25	2.45508429926238	0.115528978600604	0.349686388461508
GO:0016361	activin receptor activity, type I	3/1898	12/18639	0.25	2.45508429926238	0.115528978600604	0.349686388461508
GO:0016362	activin receptor activity, type II	3/1898	12/18639	0.25	2.45508429926238	0.115528978600604	0.349686388461508
GO:0016423	tRNA (guanine) methyltransferase activity	3/1898	12/18639	0.25	2.45508429926238	0.115528978600604	0.349686388461508
GO:0017002	activin receptor activity	3/1898	12/18639	0.25	2.45508429926238	0.115528978600604	0.349686388461508
GO:0034452	dynactin binding	3/1898	12/18639	0.25	2.45508429926238	0.115528978600604	0.349686388461508
GO:0035259	nuclear glucocorticoid receptor binding	3/1898	12/18639	0.25	2.45508429926238	0.115528978600604	0.349686388461508
GO:0042301	phosphate ion binding	3/1898	12/18639	0.25	2.45508429926238	0.115528978600604	0.349686388461508
GO:0043047	single-stranded telomeric DNA binding	3/1898	12/18639	0.25	2.45508429926238	0.115528978600604	0.349686388461508
GO:0045295	gamma-catenin binding	3/1898	12/18639	0.25	2.45508429926238	0.115528978600604	0.349686388461508
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	3/1898	12/18639	0.25	2.45508429926238	0.115528978600604	0.349686388461508
GO:0070410	co-SMAD binding	3/1898	12/18639	0.25	2.45508429926238	0.115528978600604	0.349686388461508
GO:1990247	N6-methyladenosine-containing RNA reader activity	3/1898	12/18639	0.25	2.45508429926238	0.115528978600604	0.349686388461508
GO:0003727	single-stranded RNA binding	13/1898	89/18639	0.146067415730337	1.43443127597353	0.116470166446003	0.349686388461508
GO:0061650	ubiquitin-like protein conjugating enzyme activity	7/1898	41/18639	0.170731707317073	1.67664293608163	0.118126146079792	0.349686388461508
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	5/1898	26/18639	0.192307692307692	1.88852638404799	0.118374142590714	0.349686388461508
GO:0030507	spectrin binding	5/1898	26/18639	0.192307692307692	1.88852638404799	0.118374142590714	0.349686388461508
GO:0033192	calmodulin-dependent protein phosphatase activity	12/1898	81/18639	0.148148148148148	1.45486476993326	0.118391248761277	0.349686388461508
GO:0140791	histone H2AXS140 phosphatase activity	12/1898	81/18639	0.148148148148148	1.45486476993326	0.118391248761277	0.349686388461508
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	12/1898	81/18639	0.148148148148148	1.45486476993326	0.118391248761277	0.349686388461508
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	12/1898	81/18639	0.148148148148148	1.45486476993326	0.118391248761277	0.349686388461508
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	12/1898	81/18639	0.148148148148148	1.45486476993326	0.118391248761277	0.349686388461508
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	12/1898	81/18639	0.148148148148148	1.45486476993326	0.118391248761277	0.349686388461508
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	12/1898	81/18639	0.148148148148148	1.45486476993326	0.118391248761277	0.349686388461508
GO:1990439	MAP kinase serine/threonine phosphatase activity	12/1898	81/18639	0.148148148148148	1.45486476993326	0.118391248761277	0.349686388461508
GO:0004713	protein tyrosine kinase activity	19/1898	140/18639	0.135714285714286	1.33276004817101	0.119179928188382	0.349686388461508
GO:0003756	protein disulfide isomerase activity	4/1898	19/18639	0.210526315789474	2.06743940990516	0.12080589633743	0.349686388461508
GO:0005346	purine ribonucleotide transmembrane transporter activity	4/1898	19/18639	0.210526315789474	2.06743940990516	0.12080589633743	0.349686388461508
GO:0008301	DNA binding, bending	4/1898	19/18639	0.210526315789474	2.06743940990516	0.12080589633743	0.349686388461508
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	4/1898	19/18639	0.210526315789474	2.06743940990516	0.12080589633743	0.349686388461508
GO:0030506	ankyrin binding	4/1898	19/18639	0.210526315789474	2.06743940990516	0.12080589633743	0.349686388461508
GO:0046624	sphingolipid transporter activity	4/1898	19/18639	0.210526315789474	2.06743940990516	0.12080589633743	0.349686388461508
GO:0050145	nucleoside monophosphate kinase activity	4/1898	19/18639	0.210526315789474	2.06743940990516	0.12080589633743	0.349686388461508
GO:1990380	K48-linked deubiquitinase activity	4/1898	19/18639	0.210526315789474	2.06743940990516	0.12080589633743	0.349686388461508
GO:0016504	peptidase activator activity	9/1898	57/18639	0.157894736842105	1.55057955742887	0.121329583840753	0.350213060731873
GO:0008170	N-methyltransferase activity	14/1898	98/18639	0.142857142857143	1.40290531386422	0.121554533215189	0.350213060731873
GO:0016874	ligase activity	22/1898	167/18639	0.131736526946108	1.29369711577898	0.125700994199146	0.361317276349174
GO:0015035	protein-disulfide reductase activity	6/1898	34/18639	0.176470588235294	1.73300068183227	0.126196093138066	0.361898772897099
GO:0033549	MAP kinase phosphatase activity	12/1898	82/18639	0.146341463414634	1.43712251664139	0.126573531300559	0.362140936776599
GO:0141003	histone H2AX kinase activity	43/1898	354/18639	0.121468926553672	1.19286581772071	0.12730989815972	0.363406545324283
GO:0015294	solute:monoatomic cation symporter activity	16/1898	116/18639	0.137931034482759	1.35452926855856	0.129666411457239	0.368591423720868
GO:0035198	miRNA binding	7/1898	42/18639	0.166666666666667	1.63672286617492	0.130020922930662	0.368591423720868
GO:0043175	RNA polymerase core enzyme binding	7/1898	42/18639	0.166666666666667	1.63672286617492	0.130020922930662	0.368591423720868
GO:0072341	modified amino acid binding	13/1898	91/18639	0.142857142857143	1.40290531386422	0.132133548229818	0.37372326227015
GO:0005044	scavenger receptor activity	5/1898	27/18639	0.185185185185185	1.81858096241658	0.133784037443364	0.375811523363631
GO:0005385	zinc ion transmembrane transporter activity	5/1898	27/18639	0.185185185185185	1.81858096241658	0.133784037443364	0.375811523363631
GO:0035255	ionotropic glutamate receptor binding	5/1898	27/18639	0.185185185185185	1.81858096241658	0.133784037443364	0.375811523363631
GO:0004535	poly(A)-specific ribonuclease activity	3/1898	13/18639	0.230769230769231	2.26623166085758	0.139336604211256	0.381440477487205
GO:0008035	high-density lipoprotein particle binding	3/1898	13/18639	0.230769230769231	2.26623166085758	0.139336604211256	0.381440477487205
GO:0019104	DNA N-glycosylase activity	3/1898	13/18639	0.230769230769231	2.26623166085758	0.139336604211256	0.381440477487205
GO:0061459	L-arginine transmembrane transporter activity	3/1898	13/18639	0.230769230769231	2.26623166085758	0.139336604211256	0.381440477487205
GO:0140852	histone ubiquitin ligase activity	3/1898	13/18639	0.230769230769231	2.26623166085758	0.139336604211256	0.381440477487205
GO:0140996	histone H3 kinase activity	43/1898	357/18639	0.120448179271709	1.18284173521885	0.139357964643187	0.381440477487205
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	4/1898	20/18639	0.2	1.96406743940991	0.139491177851308	0.381440477487205
GO:0005326	neurotransmitter transmembrane transporter activity	4/1898	20/18639	0.2	1.96406743940991	0.139491177851308	0.381440477487205
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	4/1898	20/18639	0.2	1.96406743940991	0.139491177851308	0.381440477487205
GO:0030742	GTP-dependent protein binding	4/1898	20/18639	0.2	1.96406743940991	0.139491177851308	0.381440477487205
GO:0061608	nuclear import signal receptor activity	4/1898	20/18639	0.2	1.96406743940991	0.139491177851308	0.381440477487205
GO:0140939	histone H4 methyltransferase activity	4/1898	20/18639	0.2	1.96406743940991	0.139491177851308	0.381440477487205
GO:0061631	ubiquitin conjugating enzyme activity	6/1898	35/18639	0.171428571428571	1.68348637663706	0.13996784667906	0.381899025375979
GO:0005021	vascular endothelial growth factor receptor activity	8/1898	51/18639	0.156862745098039	1.54044505051757	0.142859824183114	0.388076357561162
GO:0016597	amino acid binding	8/1898	51/18639	0.156862745098039	1.54044505051757	0.142859824183114	0.388076357561162
GO:0017018	myosin phosphatase activity	12/1898	84/18639	0.142857142857143	1.40290531386422	0.143854923973448	0.389922557085924
GO:0046943	carboxylic acid transmembrane transporter activity	24/1898	188/18639	0.127659574468085	1.25366006770845	0.145926998493843	0.394673457633239
GO:0019207	kinase regulator activity	35/1898	287/18639	0.121951219512195	1.19760209720116	0.149920514237044	0.40401317383845
GO:0051393	alpha-actinin binding	5/1898	28/18639	0.178571428571429	1.75363164233027	0.150034018440007	0.40401317383845
GO:0005342	organic acid transmembrane transporter activity	24/1898	189/18639	0.126984126984127	1.24702694565708	0.151908688299962	0.407748562738413
GO:0035173	histone kinase activity	43/1898	360/18639	0.119444444444444	1.17298472075869	0.152080976878971	0.407748562738413
GO:0004190	aspartic-type endopeptidase activity	6/1898	36/18639	0.166666666666667	1.63672286617492	0.154400897064638	0.409512297273075
GO:0044390	ubiquitin-like protein conjugating enzyme binding	6/1898	36/18639	0.166666666666667	1.63672286617492	0.154400897064638	0.409512297273075
GO:0045505	dynein intermediate chain binding	6/1898	36/18639	0.166666666666667	1.63672286617492	0.154400897064638	0.409512297273075
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	17/1898	128/18639	0.1328125	1.30426353398314	0.154465486619567	0.409512297273075
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	8/1898	52/18639	0.153846153846154	1.51082110723839	0.154726733678419	0.409512297273075
GO:0030159	signaling receptor complex adaptor activity	8/1898	52/18639	0.153846153846154	1.51082110723839	0.154726733678419	0.409512297273075
GO:1902936	phosphatidylinositol bisphosphate binding	15/1898	111/18639	0.135135135135135	1.32707259419588	0.156638273627864	0.41368569701718
GO:0042562	hormone binding	13/1898	94/18639	0.138297872340426	1.35813174001749	0.157698424293053	0.415597553147577
GO:0005123	death receptor binding	4/1898	21/18639	0.19047619047619	1.87054041848562	0.159237694427962	0.418761255985023
GO:0032182	ubiquitin-like protein binding	16/1898	120/18639	0.133333333333333	1.30937829293994	0.159585783645307	0.418785623323991
GO:0035591	signaling adaptor activity	17/1898	129/18639	0.131782945736434	1.29415296395226	0.162053081479625	0.423871567214569
GO:0005347	ATP transmembrane transporter activity	3/1898	14/18639	0.214285714285714	2.10435797079633	0.164610317364881	0.423871567214569
GO:0008195	phosphatidate phosphatase activity	3/1898	14/18639	0.214285714285714	2.10435797079633	0.164610317364881	0.423871567214569
GO:0031404	chloride ion binding	3/1898	14/18639	0.214285714285714	2.10435797079633	0.164610317364881	0.423871567214569
GO:0044548	S100 protein binding	3/1898	14/18639	0.214285714285714	2.10435797079633	0.164610317364881	0.423871567214569
GO:0071933	Arp2/3 complex binding	3/1898	14/18639	0.214285714285714	2.10435797079633	0.164610317364881	0.423871567214569
GO:0098821	BMP receptor activity	3/1898	14/18639	0.214285714285714	2.10435797079633	0.164610317364881	0.423871567214569
GO:0098847	sequence-specific single stranded DNA binding	3/1898	14/18639	0.214285714285714	2.10435797079633	0.164610317364881	0.423871567214569
GO:1901474	azole transmembrane transporter activity	3/1898	14/18639	0.214285714285714	2.10435797079633	0.164610317364881	0.423871567214569
GO:0017046	peptide hormone binding	8/1898	53/18639	0.150943396226415	1.48231504861125	0.167045227449863	0.428404788240659
GO:0003785	actin monomer binding	5/1898	29/18639	0.172413793103448	1.69316158569819	0.167064003181228	0.428404788240659
GO:0051539	4 iron, 4 sulfur cluster binding	7/1898	45/18639	0.155555555555556	1.52760800842993	0.169038463944038	0.432570479161141
GO:0070001	aspartic-type peptidase activity	6/1898	37/18639	0.162162162162162	1.59248711303506	0.169457201510438	0.432746076584507
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	56/1898	484/18639	0.115702479338843	1.13623736164209	0.171352340103124	0.436683489417445
GO:0015179	L-amino acid transmembrane transporter activity	9/1898	62/18639	0.145161290322581	1.42553281892654	0.175827464671164	0.447166144719256
GO:0016835	carbon-oxygen lyase activity	11/1898	79/18639	0.139240506329114	1.36738872363981	0.177288901548427	0.449957047872395
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	8/1898	54/18639	0.148148148148148	1.45486476993326	0.179794991550501	0.452023521666397
GO:0008093	cytoskeletal anchor activity	4/1898	22/18639	0.181818181818182	1.785515854009	0.179931693090508	0.452023521666397
GO:0034062	5'-3' RNA polymerase activity	4/1898	22/18639	0.181818181818182	1.785515854009	0.179931693090508	0.452023521666397
GO:0097747	RNA polymerase activity	4/1898	22/18639	0.181818181818182	1.785515854009	0.179931693090508	0.452023521666397
GO:0140517	protein-RNA adaptor activity	4/1898	22/18639	0.181818181818182	1.785515854009	0.179931693090508	0.452023521666397
GO:0005085	guanyl-nucleotide exchange factor activity	28/1898	230/18639	0.121739130434783	1.19551931094516	0.183716118053788	0.458683419169113
GO:0001968	fibronectin binding	5/1898	30/18639	0.166666666666667	1.63672286617492	0.184809338791439	0.458683419169113
GO:0015215	nucleotide transmembrane transporter activity	5/1898	30/18639	0.166666666666667	1.63672286617492	0.184809338791439	0.458683419169113
GO:0016769	transferase activity, transferring nitrogenous groups	5/1898	30/18639	0.166666666666667	1.63672286617492	0.184809338791439	0.458683419169113
GO:0031624	ubiquitin conjugating enzyme binding	5/1898	30/18639	0.166666666666667	1.63672286617492	0.184809338791439	0.458683419169113
GO:0035925	mRNA 3'-UTR AU-rich region binding	5/1898	30/18639	0.166666666666667	1.63672286617492	0.184809338791439	0.458683419169113
GO:0008168	methyltransferase activity	25/1898	204/18639	0.122549019607843	1.20347269571685	0.19059695477012	0.471447070708727
GO:0005402	carbohydrate:monoatomic cation symporter activity	3/1898	15/18639	0.2	1.96406743940991	0.191096264097955	0.471447070708727
GO:0010181	FMN binding	3/1898	15/18639	0.2	1.96406743940991	0.191096264097955	0.471447070708727
GO:0008374	O-acyltransferase activity	8/1898	55/18639	0.145454545454545	1.4284126832072	0.192953961927719	0.474137369667318
GO:0140313	molecular sequestering activity	8/1898	55/18639	0.145454545454545	1.4284126832072	0.192953961927719	0.474137369667318
GO:0042626	ATPase-coupled transmembrane transporter activity	13/1898	98/18639	0.13265306122449	1.30269779144535	0.19541685315276	0.479236568446053
GO:0019888	protein phosphatase regulator activity	14/1898	107/18639	0.130841121495327	1.28490393232424	0.198017502248632	0.48465273817685
GO:0001216	DNA-binding transcription activator activity	56/1898	491/18639	0.114052953156823	1.12003845831929	0.200993529189198	0.487277750748353
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	6/1898	39/18639	0.153846153846154	1.51082110723839	0.201271394154029	0.487277750748353
GO:0000295	adenine nucleotide transmembrane transporter activity	4/1898	23/18639	0.173913043478261	1.70788472992166	0.201455445495476	0.487277750748353
GO:0004602	glutathione peroxidase activity	4/1898	23/18639	0.173913043478261	1.70788472992166	0.201455445495476	0.487277750748353
GO:0008171	O-methyltransferase activity	4/1898	23/18639	0.173913043478261	1.70788472992166	0.201455445495476	0.487277750748353
GO:0140103	catalytic activity, acting on a glycoprotein	4/1898	23/18639	0.173913043478261	1.70788472992166	0.201455445495476	0.487277750748353
GO:0016741	transferase activity, transferring one-carbon groups	26/1898	215/18639	0.12093023255814	1.18757566103855	0.203764281481137	0.491899710763056
GO:0019208	phosphatase regulator activity	15/1898	117/18639	0.128205128205128	1.25901758936532	0.209352232805963	0.504404210035419
GO:0016879	ligase activity, forming carbon-nitrogen bonds	7/1898	48/18639	0.145833333333333	1.43213250790306	0.212489843936711	0.510967795925633
GO:0015144	carbohydrate transmembrane transporter activity	6/1898	40/18639	0.15	1.47305057955743	0.217938798783563	0.51947037444384
GO:0003688	DNA replication origin binding	3/1898	16/18639	0.1875	1.84131322444679	0.218547406723946	0.51947037444384
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	3/1898	16/18639	0.1875	1.84131322444679	0.218547406723946	0.51947037444384
GO:0005324	long-chain fatty acid transmembrane transporter activity	3/1898	16/18639	0.1875	1.84131322444679	0.218547406723946	0.51947037444384
GO:0070411	I-SMAD binding	3/1898	16/18639	0.1875	1.84131322444679	0.218547406723946	0.51947037444384
GO:0140327	flippase activity	3/1898	16/18639	0.1875	1.84131322444679	0.218547406723946	0.51947037444384
GO:0004601	peroxidase activity	8/1898	57/18639	0.140350877192982	1.37829293993678	0.220403642790515	0.52287697214794
GO:0015149	hexose transmembrane transporter activity	4/1898	24/18639	0.166666666666667	1.63672286617492	0.223689449356309	0.527633891993126
GO:0048027	mRNA 5'-UTR binding	4/1898	24/18639	0.166666666666667	1.63672286617492	0.223689449356309	0.527633891993126
GO:0055056	D-glucose transmembrane transporter activity	4/1898	24/18639	0.166666666666667	1.63672286617492	0.223689449356309	0.527633891993126
GO:0019887	protein kinase regulator activity	30/1898	255/18639	0.117647058823529	1.15533378788818	0.226867467441838	0.534110837634499
GO:0016763	pentosyltransferase activity	7/1898	49/18639	0.142857142857143	1.40290531386422	0.227812786459	0.535316737762974
GO:0008408	3'-5' exonuclease activity	8/1898	58/18639	0.137931034482759	1.35452926855856	0.23464317947754	0.546092538551454
GO:0061980	regulatory RNA binding	8/1898	58/18639	0.137931034482759	1.35452926855856	0.23464317947754	0.546092538551454
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	6/1898	41/18639	0.146341463414634	1.43712251664139	0.235049539247066	0.546092538551454
GO:0017080	sodium channel regulator activity	6/1898	41/18639	0.146341463414634	1.43712251664139	0.235049539247066	0.546092538551454
GO:0042169	SH2 domain binding	6/1898	41/18639	0.146341463414634	1.43712251664139	0.235049539247066	0.546092538551454
GO:0140318	protein transporter activity	6/1898	41/18639	0.146341463414634	1.43712251664139	0.235049539247066	0.546092538551454
GO:0030296	protein tyrosine kinase activator activity	5/1898	33/18639	0.151515151515152	1.48792987834084	0.241644350872069	0.555474566020093
GO:0140311	protein sequestering activity	5/1898	33/18639	0.151515151515152	1.48792987834084	0.241644350872069	0.555474566020093
GO:0051536	iron-sulfur cluster binding	10/1898	76/18639	0.131578947368421	1.29214963119073	0.242814680204882	0.555474566020093
GO:0005006	epidermal growth factor receptor activity	7/1898	50/18639	0.14	1.37484720758693	0.243497654594914	0.555474566020093
GO:0032813	tumor necrosis factor receptor superfamily binding	7/1898	50/18639	0.14	1.37484720758693	0.243497654594914	0.555474566020093
GO:0000030	mannosyltransferase activity	4/1898	25/18639	0.16	1.57125395152792	0.246514346547176	0.555474566020093
GO:0004709	MAP kinase kinase kinase activity	4/1898	25/18639	0.16	1.57125395152792	0.246514346547176	0.555474566020093
GO:0005537	D-mannose binding	4/1898	25/18639	0.16	1.57125395152792	0.246514346547176	0.555474566020093
GO:0008483	transaminase activity	4/1898	25/18639	0.16	1.57125395152792	0.246514346547176	0.555474566020093
GO:0019211	phosphatase activator activity	4/1898	25/18639	0.16	1.57125395152792	0.246514346547176	0.555474566020093
GO:0004029	aldehyde dehydrogenase (NAD+) activity	3/1898	17/18639	0.176470588235294	1.73300068183227	0.246727780538051	0.555474566020093
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	3/1898	17/18639	0.176470588235294	1.73300068183227	0.246727780538051	0.555474566020093
GO:0015278	intracellularly gated calcium channel activity	3/1898	17/18639	0.176470588235294	1.73300068183227	0.246727780538051	0.555474566020093
GO:0016805	dipeptidase activity	3/1898	17/18639	0.176470588235294	1.73300068183227	0.246727780538051	0.555474566020093
GO:0017110	nucleoside diphosphate phosphatase activity	3/1898	17/18639	0.176470588235294	1.73300068183227	0.246727780538051	0.555474566020093
GO:0070402	NADPH binding	3/1898	17/18639	0.176470588235294	1.73300068183227	0.246727780538051	0.555474566020093
GO:1990226	histone methyltransferase binding	3/1898	17/18639	0.176470588235294	1.73300068183227	0.246727780538051	0.555474566020093
GO:0004879	nuclear receptor activity	8/1898	59/18639	0.135593220338983	1.33157114536265	0.249189962135455	0.55898147586102
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	8/1898	59/18639	0.135593220338983	1.33157114536265	0.249189962135455	0.55898147586102
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	31/1898	268/18639	0.115671641791045	1.13593452652439	0.252044870298071	0.563460515289808
GO:0004520	DNA endonuclease activity	6/1898	42/18639	0.142857142857143	1.40290531386422	0.252554308633134	0.563460515289808
GO:0019894	kinesin binding	6/1898	42/18639	0.142857142857143	1.40290531386422	0.252554308633134	0.563460515289808
GO:0005548	phospholipid transporter activity	9/1898	68/18639	0.132352941176471	1.2997505113742	0.253051795531763	0.563553187886954
GO:0051540	metal cluster binding	10/1898	77/18639	0.12987012987013	1.27536846714929	0.255638295756125	0.568289448839155
GO:0001217	DNA-binding transcription repressor activity	32/1898	278/18639	0.115107913669065	1.13039852627908	0.256898748858484	0.569941156111549
GO:0016209	antioxidant activity	11/1898	86/18639	0.127906976744186	1.25608964148308	0.257303531642593	0.569941156111549
GO:0005010	insulin-like growth factor receptor activity	7/1898	51/18639	0.137254901960784	1.34788941920288	0.259508218524065	0.573527254085647
GO:0008175	tRNA methyltransferase activity	5/1898	34/18639	0.147058823529412	1.44416723486022	0.261549222895173	0.573527254085647
GO:0015020	glucuronosyltransferase activity	5/1898	34/18639	0.147058823529412	1.44416723486022	0.261549222895173	0.573527254085647
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	5/1898	34/18639	0.147058823529412	1.44416723486022	0.261549222895173	0.573527254085647
GO:0098531	ligand-modulated transcription factor activity	8/1898	60/18639	0.133333333333333	1.30937829293994	0.264016038925091	0.573527254085647
GO:0008081	phosphoric diester hydrolase activity	11/1898	87/18639	0.126436781609195	1.24165182951201	0.269652705346625	0.573527254085647
GO:0005112	Notch binding	4/1898	26/18639	0.153846153846154	1.51082110723839	0.26981256544835	0.573527254085647
GO:0015145	monosaccharide transmembrane transporter activity	4/1898	26/18639	0.153846153846154	1.51082110723839	0.26981256544835	0.573527254085647
GO:0015216	purine nucleotide transmembrane transporter activity	4/1898	26/18639	0.153846153846154	1.51082110723839	0.26981256544835	0.573527254085647
GO:0034237	protein kinase A regulatory subunit binding	4/1898	26/18639	0.153846153846154	1.51082110723839	0.26981256544835	0.573527254085647
GO:0052742	phosphatidylinositol kinase activity	4/1898	26/18639	0.153846153846154	1.51082110723839	0.26981256544835	0.573527254085647
GO:0097602	cullin family protein binding	4/1898	26/18639	0.153846153846154	1.51082110723839	0.26981256544835	0.573527254085647
GO:0001094	TFIID-class transcription factor complex binding	2/1898	10/18639	0.2	1.96406743940991	0.270986987367329	0.573527254085647
GO:0004382	GDP phosphatase activity	2/1898	10/18639	0.2	1.96406743940991	0.270986987367329	0.573527254085647
GO:0015658	branched-chain amino acid transmembrane transporter activity	2/1898	10/18639	0.2	1.96406743940991	0.270986987367329	0.573527254085647
GO:0016175	superoxide-generating NAD(P)H oxidase activity	2/1898	10/18639	0.2	1.96406743940991	0.270986987367329	0.573527254085647
GO:0016303	1-phosphatidylinositol-3-kinase activity	2/1898	10/18639	0.2	1.96406743940991	0.270986987367329	0.573527254085647
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	2/1898	10/18639	0.2	1.96406743940991	0.270986987367329	0.573527254085647
GO:0019911	structural constituent of myelin sheath	2/1898	10/18639	0.2	1.96406743940991	0.270986987367329	0.573527254085647
GO:0042975	peroxisome proliferator activated receptor binding	2/1898	10/18639	0.2	1.96406743940991	0.270986987367329	0.573527254085647
GO:0043295	glutathione binding	2/1898	10/18639	0.2	1.96406743940991	0.270986987367329	0.573527254085647
GO:0043422	protein kinase B binding	2/1898	10/18639	0.2	1.96406743940991	0.270986987367329	0.573527254085647
GO:0051880	G-quadruplex DNA binding	2/1898	10/18639	0.2	1.96406743940991	0.270986987367329	0.573527254085647
GO:0098505	G-rich strand telomeric DNA binding	2/1898	10/18639	0.2	1.96406743940991	0.270986987367329	0.573527254085647
GO:0140940	histone H2A methyltransferase activity	2/1898	10/18639	0.2	1.96406743940991	0.270986987367329	0.573527254085647
GO:1990259	histone H2AQ104 methyltransferase activity	2/1898	10/18639	0.2	1.96406743940991	0.270986987367329	0.573527254085647
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	3/1898	18/18639	0.166666666666667	1.63672286617492	0.275415508019543	0.574870396147387
GO:0004706	JUN kinase kinase kinase activity	3/1898	18/18639	0.166666666666667	1.63672286617492	0.275415508019543	0.574870396147387
GO:0008308	voltage-gated monoatomic anion channel activity	3/1898	18/18639	0.166666666666667	1.63672286617492	0.275415508019543	0.574870396147387
GO:0008525	phosphatidylcholine transporter activity	3/1898	18/18639	0.166666666666667	1.63672286617492	0.275415508019543	0.574870396147387
GO:0031690	adrenergic receptor binding	3/1898	18/18639	0.166666666666667	1.63672286617492	0.275415508019543	0.574870396147387
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	3/1898	18/18639	0.166666666666667	1.63672286617492	0.275415508019543	0.574870396147387
GO:0098641	cadherin binding involved in cell-cell adhesion	3/1898	18/18639	0.166666666666667	1.63672286617492	0.275415508019543	0.574870396147387
GO:1990381	ubiquitin-specific protease binding	3/1898	18/18639	0.166666666666667	1.63672286617492	0.275415508019543	0.574870396147387
GO:0005080	protein kinase C binding	7/1898	52/18639	0.134615384615385	1.32196846883359	0.275807560611165	0.574870396147387
GO:0015026	coreceptor activity	8/1898	61/18639	0.131147540983607	1.28791307502289	0.27909285392573	0.580738665744449
GO:0097110	scaffold protein binding	9/1898	70/18639	0.128571428571429	1.2626147824778	0.280988093215919	0.583451596313154
GO:0000175	3'-5'-RNA exonuclease activity	5/1898	35/18639	0.142857142857143	1.40290531386422	0.281812785597858	0.583451596313154
GO:0140566	histone reader activity	5/1898	35/18639	0.142857142857143	1.40290531386422	0.281812785597858	0.583451596313154
GO:0001223	transcription coactivator binding	6/1898	44/18639	0.136363636363636	1.33913689050675	0.288545390124955	0.593414479524865
GO:0016248	channel inhibitor activity	6/1898	44/18639	0.136363636363636	1.33913689050675	0.288545390124955	0.593414479524865
GO:0016790	thiolester hydrolase activity	6/1898	44/18639	0.136363636363636	1.33913689050675	0.288545390124955	0.593414479524865
GO:0043014	alpha-tubulin binding	6/1898	44/18639	0.136363636363636	1.33913689050675	0.288545390124955	0.593414479524865
GO:0004864	protein phosphatase inhibitor activity	7/1898	53/18639	0.132075471698113	1.29702566753484	0.292358350440059	0.598561963913213
GO:0140296	general transcription initiation factor binding	7/1898	53/18639	0.132075471698113	1.29702566753484	0.292358350440059	0.598561963913213
GO:0004364	glutathione transferase activity	4/1898	27/18639	0.148148148148148	1.45486476993326	0.293469700753566	0.598561963913213
GO:0015252	proton channel activity	4/1898	27/18639	0.148148148148148	1.45486476993326	0.293469700753566	0.598561963913213
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	4/1898	27/18639	0.148148148148148	1.45486476993326	0.293469700753566	0.598561963913213
GO:0019955	cytokine binding	17/1898	144/18639	0.118055555555556	1.15934536354057	0.296438560201109	0.603621186834548
GO:0008381	mechanosensitive monoatomic ion channel activity	3/1898	19/18639	0.157894736842105	1.55057955742887	0.30440481020994	0.614912686959521
GO:0015245	fatty acid transmembrane transporter activity	3/1898	19/18639	0.157894736842105	1.55057955742887	0.30440481020994	0.614912686959521
GO:0031420	alkali metal ion binding	3/1898	19/18639	0.157894736842105	1.55057955742887	0.30440481020994	0.614912686959521
GO:0005496	steroid binding	13/1898	108/18639	0.12037037037037	1.18207762557078	0.304517315521753	0.614912686959521
GO:0141110	transporter inhibitor activity	6/1898	45/18639	0.133333333333333	1.30937829293994	0.306931071075865	0.614912686959521
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	2/1898	11/18639	0.181818181818182	1.785515854009	0.310441356523253	0.614912686959521
GO:0008271	secondary active sulfate transmembrane transporter activity	2/1898	11/18639	0.181818181818182	1.785515854009	0.310441356523253	0.614912686959521
GO:0008503	benzodiazepine receptor activity	2/1898	11/18639	0.181818181818182	1.785515854009	0.310441356523253	0.614912686959521
GO:0015217	ADP transmembrane transporter activity	2/1898	11/18639	0.181818181818182	1.785515854009	0.310441356523253	0.614912686959521
GO:0016594	glycine binding	2/1898	11/18639	0.181818181818182	1.785515854009	0.310441356523253	0.614912686959521
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	2/1898	11/18639	0.181818181818182	1.785515854009	0.310441356523253	0.614912686959521
GO:0034511	U3 snoRNA binding	2/1898	11/18639	0.181818181818182	1.785515854009	0.310441356523253	0.614912686959521
GO:0035252	UDP-xylosyltransferase activity	2/1898	11/18639	0.181818181818182	1.785515854009	0.310441356523253	0.614912686959521
GO:0042285	xylosyltransferase activity	2/1898	11/18639	0.181818181818182	1.785515854009	0.310441356523253	0.614912686959521
GO:0050786	RAGE receptor binding	2/1898	11/18639	0.181818181818182	1.785515854009	0.310441356523253	0.614912686959521
GO:0140537	transcription regulator activator activity	2/1898	11/18639	0.181818181818182	1.785515854009	0.310441356523253	0.614912686959521
GO:1900750	oligopeptide binding	2/1898	11/18639	0.181818181818182	1.785515854009	0.310441356523253	0.614912686959521
GO:0050698	proteoglycan sulfotransferase activity	4/1898	28/18639	0.142857142857143	1.40290531386422	0.317375647805825	0.624643790904459
GO:0051119	sugar transmembrane transporter activity	4/1898	28/18639	0.142857142857143	1.40290531386422	0.317375647805825	0.624643790904459
GO:0051537	2 iron, 2 sulfur cluster binding	4/1898	28/18639	0.142857142857143	1.40290531386422	0.317375647805825	0.624643790904459
GO:0051959	dynein light intermediate chain binding	4/1898	28/18639	0.142857142857143	1.40290531386422	0.317375647805825	0.624643790904459
GO:0043130	ubiquitin binding	12/1898	100/18639	0.12	1.17844046364594	0.318584700158214	0.626026533220274
GO:0015103	inorganic anion transmembrane transporter activity	19/1898	165/18639	0.115151515151515	1.13082670753904	0.320576292170233	0.628940154162553
GO:0042805	actinin binding	5/1898	37/18639	0.135135135135135	1.32707259419588	0.323129635307733	0.631943400696769
GO:0043394	proteoglycan binding	5/1898	37/18639	0.135135135135135	1.32707259419588	0.323129635307733	0.631943400696769
GO:0004222	metalloendopeptidase activity	13/1898	110/18639	0.118181818181818	1.16058530510585	0.328190797978663	0.640827529702414
GO:0015095	magnesium ion transmembrane transporter activity	3/1898	20/18639	0.15	1.47305057955743	0.333507215920285	0.649157352562949
GO:0016408	C-acyltransferase activity	3/1898	20/18639	0.15	1.47305057955743	0.333507215920285	0.649157352562949
GO:0001540	amyloid-beta binding	10/1898	83/18639	0.120481927710843	1.18317315627103	0.336537921947026	0.651414564834419
GO:0005539	glycosaminoglycan binding	27/1898	242/18639	0.111570247933884	1.09565745586916	0.337064644979699	0.651414564834419
GO:0019212	phosphatase inhibitor activity	7/1898	56/18639	0.125	1.22754214963119	0.343145286364558	0.651414564834419
GO:0030170	pyridoxal phosphate binding	7/1898	56/18639	0.125	1.22754214963119	0.343145286364558	0.651414564834419
GO:0000146	microfilament motor activity	5/1898	38/18639	0.131578947368421	1.29214963119073	0.344043912172057	0.651414564834419
GO:0005109	frizzled binding	5/1898	38/18639	0.131578947368421	1.29214963119073	0.344043912172057	0.651414564834419
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	5/1898	38/18639	0.131578947368421	1.29214963119073	0.344043912172057	0.651414564834419
GO:0043531	ADP binding	5/1898	38/18639	0.131578947368421	1.29214963119073	0.344043912172057	0.651414564834419
GO:0043021	ribonucleoprotein complex binding	20/1898	177/18639	0.112994350282486	1.10964262113554	0.34585025163549	0.651414564834419
GO:0051219	phosphoprotein binding	11/1898	93/18639	0.118279569892473	1.16154525986607	0.347053721937216	0.651414564834419
GO:0004526	ribonuclease P activity	2/1898	12/18639	0.166666666666667	1.63672286617492	0.349423832107783	0.651414564834419
GO:0005049	nuclear export signal receptor activity	2/1898	12/18639	0.166666666666667	1.63672286617492	0.349423832107783	0.651414564834419
GO:0005165	neurotrophin receptor binding	2/1898	12/18639	0.166666666666667	1.63672286617492	0.349423832107783	0.651414564834419
GO:0008504	monoamine transmembrane transporter activity	2/1898	12/18639	0.166666666666667	1.63672286617492	0.349423832107783	0.651414564834419
GO:0015166	polyol transmembrane transporter activity	2/1898	12/18639	0.166666666666667	1.63672286617492	0.349423832107783	0.651414564834419
GO:0016273	arginine N-methyltransferase activity	2/1898	12/18639	0.166666666666667	1.63672286617492	0.349423832107783	0.651414564834419
GO:0016274	protein-arginine N-methyltransferase activity	2/1898	12/18639	0.166666666666667	1.63672286617492	0.349423832107783	0.651414564834419
GO:0035014	phosphatidylinositol 3-kinase regulator activity	2/1898	12/18639	0.166666666666667	1.63672286617492	0.349423832107783	0.651414564834419
GO:0035197	siRNA binding	2/1898	12/18639	0.166666666666667	1.63672286617492	0.349423832107783	0.651414564834419
GO:0035497	cAMP response element binding	2/1898	12/18639	0.166666666666667	1.63672286617492	0.349423832107783	0.651414564834419
GO:0036009	protein-glutamine N-methyltransferase activity	2/1898	12/18639	0.166666666666667	1.63672286617492	0.349423832107783	0.651414564834419
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	2/1898	12/18639	0.166666666666667	1.63672286617492	0.349423832107783	0.651414564834419
GO:0070008	serine-type exopeptidase activity	2/1898	12/18639	0.166666666666667	1.63672286617492	0.349423832107783	0.651414564834419
GO:0097677	STAT family protein binding	2/1898	12/18639	0.166666666666667	1.63672286617492	0.349423832107783	0.651414564834419
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	2/1898	12/18639	0.166666666666667	1.63672286617492	0.349423832107783	0.651414564834419
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	2/1898	12/18639	0.166666666666667	1.63672286617492	0.349423832107783	0.651414564834419
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	2/1898	12/18639	0.166666666666667	1.63672286617492	0.349423832107783	0.651414564834419
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	2/1898	12/18639	0.166666666666667	1.63672286617492	0.349423832107783	0.651414564834419
GO:0005200	structural constituent of cytoskeleton	13/1898	112/18639	0.116071428571429	1.13986056751468	0.352257106605184	0.655707505668685
GO:0031072	heat shock protein binding	15/1898	131/18639	0.114503816793893	1.12446609126521	0.355746894010648	0.661207760897987
GO:0070279	vitamin B6 binding	7/1898	57/18639	0.12280701754386	1.20600632244468	0.360329116464923	0.665846122295532
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	3/1898	21/18639	0.142857142857143	1.40290531386422	0.362552136169007	0.665846122295532
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	3/1898	21/18639	0.142857142857143	1.40290531386422	0.362552136169007	0.665846122295532
GO:0010314	phosphatidylinositol-5-phosphate binding	3/1898	21/18639	0.142857142857143	1.40290531386422	0.362552136169007	0.665846122295532
GO:0015174	basic amino acid transmembrane transporter activity	3/1898	21/18639	0.142857142857143	1.40290531386422	0.362552136169007	0.665846122295532
GO:0035613	RNA stem-loop binding	3/1898	21/18639	0.142857142857143	1.40290531386422	0.362552136169007	0.665846122295532
GO:0061891	calcium ion sensor activity	3/1898	21/18639	0.142857142857143	1.40290531386422	0.362552136169007	0.665846122295532
GO:0072542	protein phosphatase activator activity	3/1898	21/18639	0.142857142857143	1.40290531386422	0.362552136169007	0.665846122295532
GO:0098918	structural constituent of synapse	4/1898	30/18639	0.133333333333333	1.30937829293994	0.365520306661811	0.670301333878336
GO:0016500	protein-hormone receptor activity	8/1898	67/18639	0.119402985074627	1.17257757576711	0.373188617782361	0.683304119535215
GO:0004867	serine-type endopeptidase inhibitor activity	11/1898	95/18639	0.115789473684211	1.13709167544784	0.373716492561331	0.683304119535215
GO:0005004	GPI-linked ephrin receptor activity	6/1898	49/18639	0.122448979591837	1.20249026902647	0.381925735003739	0.687132763412841
GO:0005008	hepatocyte growth factor receptor activity	6/1898	49/18639	0.122448979591837	1.20249026902647	0.381925735003739	0.687132763412841
GO:0005009	insulin receptor activity	6/1898	49/18639	0.122448979591837	1.20249026902647	0.381925735003739	0.687132763412841
GO:0005011	macrophage colony-stimulating factor receptor activity	6/1898	49/18639	0.122448979591837	1.20249026902647	0.381925735003739	0.687132763412841
GO:0005018	platelet-derived growth factor alpha-receptor activity	6/1898	49/18639	0.122448979591837	1.20249026902647	0.381925735003739	0.687132763412841
GO:0005020	stem cell factor receptor activity	6/1898	49/18639	0.122448979591837	1.20249026902647	0.381925735003739	0.687132763412841
GO:0008288	boss receptor activity	6/1898	49/18639	0.122448979591837	1.20249026902647	0.381925735003739	0.687132763412841
GO:0035254	glutamate receptor binding	6/1898	49/18639	0.122448979591837	1.20249026902647	0.381925735003739	0.687132763412841
GO:0036332	placental growth factor receptor activity	6/1898	49/18639	0.122448979591837	1.20249026902647	0.381925735003739	0.687132763412841
GO:0038062	protein tyrosine kinase collagen receptor activity	6/1898	49/18639	0.122448979591837	1.20249026902647	0.381925735003739	0.687132763412841
GO:0060175	brain-derived neurotrophic factor receptor activity	6/1898	49/18639	0.122448979591837	1.20249026902647	0.381925735003739	0.687132763412841
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	20/1898	181/18639	0.110497237569061	1.08512013227067	0.384468923932208	0.690346089690545
GO:0004532	RNA exonuclease activity	5/1898	40/18639	0.125	1.22754214963119	0.386054309549914	0.690346089690545
GO:0050997	quaternary ammonium group binding	5/1898	40/18639	0.125	1.22754214963119	0.386054309549914	0.690346089690545
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	2/1898	13/18639	0.153846153846154	1.51082110723839	0.387621509907151	0.690346089690545
GO:0005542	folic acid binding	2/1898	13/18639	0.153846153846154	1.51082110723839	0.387621509907151	0.690346089690545
GO:0046974	histone H3K9 methyltransferase activity	2/1898	13/18639	0.153846153846154	1.51082110723839	0.387621509907151	0.690346089690545
GO:0070700	BMP receptor binding	2/1898	13/18639	0.153846153846154	1.51082110723839	0.387621509907151	0.690346089690545
GO:0032934	sterol binding	8/1898	68/18639	0.117647058823529	1.15533378788818	0.389206860749108	0.690825550530381
GO:0005310	dicarboxylic acid transmembrane transporter activity	4/1898	31/18639	0.129032258064516	1.26714028349026	0.389567482782909	0.690825550530381
GO:0070273	phosphatidylinositol-4-phosphate binding	4/1898	31/18639	0.129032258064516	1.26714028349026	0.389567482782909	0.690825550530381
GO:0061133	endopeptidase activator activity	3/1898	22/18639	0.136363636363636	1.33913689050675	0.391386942970875	0.692066182420603
GO:0140784	metal ion sensor activity	3/1898	22/18639	0.136363636363636	1.33913689050675	0.391386942970875	0.692066182420603
GO:0001786	phosphatidylserine binding	7/1898	59/18639	0.11864406779661	1.16512475219232	0.394863418905123	0.697215979666761
GO:0005007	fibroblast growth factor receptor activity	6/1898	50/18639	0.12	1.17844046364594	0.400802291423125	0.704682264863417
GO:0005017	platelet-derived growth factor receptor activity	6/1898	50/18639	0.12	1.17844046364594	0.400802291423125	0.704682264863417
GO:0005019	platelet-derived growth factor beta-receptor activity	6/1898	50/18639	0.12	1.17844046364594	0.400802291423125	0.704682264863417
GO:0001727	lipid kinase activity	5/1898	41/18639	0.121951219512195	1.19760209720116	0.407027194314198	0.713596613010424
GO:0015175	neutral L-amino acid transmembrane transporter activity	5/1898	41/18639	0.121951219512195	1.19760209720116	0.407027194314198	0.713596613010424
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	7/1898	60/18639	0.116666666666667	1.14570600632244	0.412145148336448	0.717268431569599
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	7/1898	60/18639	0.116666666666667	1.14570600632244	0.412145148336448	0.717268431569599
GO:0030246	carbohydrate binding	30/1898	280/18639	0.107142857142857	1.05217898539816	0.412450243241772	0.717268431569599
GO:0015106	bicarbonate transmembrane transporter activity	4/1898	32/18639	0.125	1.22754214963119	0.413481274762413	0.717268431569599
GO:0030515	snoRNA binding	4/1898	32/18639	0.125	1.22754214963119	0.413481274762413	0.717268431569599
GO:1990782	protein tyrosine kinase binding	13/1898	117/18639	0.111111111111111	1.09114857744995	0.413481382326543	0.717268431569599
GO:0008237	metallopeptidase activity	20/1898	184/18639	0.108695652173913	1.06742795620104	0.413822977410558	0.717268431569599
GO:0015370	solute:sodium symporter activity	9/1898	79/18639	0.113924050632911	1.11877259206893	0.413859557075893	0.717268431569599
GO:0005030	neurotrophin receptor activity	6/1898	51/18639	0.117647058823529	1.15533378788818	0.419641501142999	0.717268431569599
GO:0005048	signal sequence binding	6/1898	51/18639	0.117647058823529	1.15533378788818	0.419641501142999	0.717268431569599
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	3/1898	23/18639	0.130434782608696	1.28091354744124	0.419876667592185	0.717268431569599
GO:0004022	alcohol dehydrogenase (NAD+) activity	3/1898	23/18639	0.130434782608696	1.28091354744124	0.419876667592185	0.717268431569599
GO:0042171	lysophosphatidic acid acyltransferase activity	3/1898	23/18639	0.130434782608696	1.28091354744124	0.419876667592185	0.717268431569599
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	3/1898	23/18639	0.130434782608696	1.28091354744124	0.419876667592185	0.717268431569599
GO:0071617	lysophospholipid acyltransferase activity	3/1898	23/18639	0.130434782608696	1.28091354744124	0.419876667592185	0.717268431569599
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	3/1898	23/18639	0.130434782608696	1.28091354744124	0.419876667592185	0.717268431569599
GO:0016782	transferase activity, transferring sulphur-containing groups	8/1898	70/18639	0.114285714285714	1.12232425109137	0.421279265324755	0.717268431569599
GO:0008474	palmitoyl-(protein) hydrolase activity	2/1898	14/18639	0.142857142857143	1.40290531386422	0.424790041997529	0.717268431569599
GO:0008559	ABC-type xenobiotic transporter activity	2/1898	14/18639	0.142857142857143	1.40290531386422	0.424790041997529	0.717268431569599
GO:0016530	metallochaperone activity	2/1898	14/18639	0.142857142857143	1.40290531386422	0.424790041997529	0.717268431569599
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	2/1898	14/18639	0.142857142857143	1.40290531386422	0.424790041997529	0.717268431569599
GO:0019992	diacylglycerol binding	2/1898	14/18639	0.142857142857143	1.40290531386422	0.424790041997529	0.717268431569599
GO:0043176	amine binding	2/1898	14/18639	0.142857142857143	1.40290531386422	0.424790041997529	0.717268431569599
GO:0046030	inositol trisphosphate phosphatase activity	2/1898	14/18639	0.142857142857143	1.40290531386422	0.424790041997529	0.717268431569599
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	2/1898	14/18639	0.142857142857143	1.40290531386422	0.424790041997529	0.717268431569599
GO:0070742	C2H2 zinc finger domain binding	2/1898	14/18639	0.142857142857143	1.40290531386422	0.424790041997529	0.717268431569599
GO:0098599	palmitoyl hydrolase activity	2/1898	14/18639	0.142857142857143	1.40290531386422	0.424790041997529	0.717268431569599
GO:0031492	nucleosomal DNA binding	5/1898	42/18639	0.119047619047619	1.16908776155351	0.427901908595423	0.720554167607551
GO:0042056	chemoattractant activity	5/1898	42/18639	0.119047619047619	1.16908776155351	0.427901908595423	0.720554167607551
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	7/1898	61/18639	0.114754098360656	1.12692394064503	0.429392667982283	0.722080731464083
GO:0140299	molecular sensor activity	8/1898	71/18639	0.112676056338028	1.10651686727319	0.437280786614998	0.734346538391491
GO:0001091	RNA polymerase II general transcription initiation factor binding	3/1898	24/18639	0.125	1.22754214963119	0.447903413054453	0.741311560693403
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	3/1898	24/18639	0.125	1.22754214963119	0.447903413054453	0.741311560693403
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	3/1898	24/18639	0.125	1.22754214963119	0.447903413054453	0.741311560693403
GO:0004622	lysophospholipase activity	3/1898	24/18639	0.125	1.22754214963119	0.447903413054453	0.741311560693403
GO:0030552	cAMP binding	3/1898	24/18639	0.125	1.22754214963119	0.447903413054453	0.741311560693403
GO:0042625	ATPase-coupled ion transmembrane transporter activity	3/1898	24/18639	0.125	1.22754214963119	0.447903413054453	0.741311560693403
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	3/1898	24/18639	0.125	1.22754214963119	0.447903413054453	0.741311560693403
GO:0046961	proton-transporting ATPase activity, rotational mechanism	3/1898	24/18639	0.125	1.22754214963119	0.447903413054453	0.741311560693403
GO:0070300	phosphatidic acid binding	3/1898	24/18639	0.125	1.22754214963119	0.447903413054453	0.741311560693403
GO:0004712	protein serine/threonine/tyrosine kinase activity	5/1898	43/18639	0.116279069767442	1.14189967407553	0.448625442879179	0.741311560693403
GO:0008200	ion channel inhibitor activity	5/1898	43/18639	0.116279069767442	1.14189967407553	0.448625442879179	0.741311560693403
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	5/1898	43/18639	0.116279069767442	1.14189967407553	0.448625442879179	0.741311560693403
GO:0008509	monoatomic anion transmembrane transporter activity	16/1898	149/18639	0.10738255033557	1.05453285337445	0.450491830064477	0.743401738263944
GO:0005003	ephrin receptor activity	6/1898	53/18639	0.113207547169811	1.11173628645844	0.457046377499676	0.745390396071693
GO:0005005	transmembrane-ephrin receptor activity	6/1898	53/18639	0.113207547169811	1.11173628645844	0.457046377499676	0.745390396071693
GO:0016860	intramolecular oxidoreductase activity	6/1898	53/18639	0.113207547169811	1.11173628645844	0.457046377499676	0.745390396071693
GO:0038064	collagen receptor activity	6/1898	53/18639	0.113207547169811	1.11173628645844	0.457046377499676	0.745390396071693
GO:0052866	phosphatidylinositol phosphate phosphatase activity	4/1898	34/18639	0.117647058823529	1.15533378788818	0.460600745642513	0.745390396071693
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	2/1898	15/18639	0.133333333333333	1.30937829293994	0.460742930905156	0.745390396071693
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	2/1898	15/18639	0.133333333333333	1.30937829293994	0.460742930905156	0.745390396071693
GO:0015116	sulfate transmembrane transporter activity	2/1898	15/18639	0.133333333333333	1.30937829293994	0.460742930905156	0.745390396071693
GO:0015556	C4-dicarboxylate transmembrane transporter activity	2/1898	15/18639	0.133333333333333	1.30937829293994	0.460742930905156	0.745390396071693
GO:0015929	hexosaminidase activity	2/1898	15/18639	0.133333333333333	1.30937829293994	0.460742930905156	0.745390396071693
GO:0016846	carbon-sulfur lyase activity	2/1898	15/18639	0.133333333333333	1.30937829293994	0.460742930905156	0.745390396071693
GO:0033130	acetylcholine receptor binding	2/1898	15/18639	0.133333333333333	1.30937829293994	0.460742930905156	0.745390396071693
GO:0045504	dynein heavy chain binding	2/1898	15/18639	0.133333333333333	1.30937829293994	0.460742930905156	0.745390396071693
GO:0047372	monoacylglycerol lipase activity	2/1898	15/18639	0.133333333333333	1.30937829293994	0.460742930905156	0.745390396071693
GO:0051371	muscle alpha-actinin binding	2/1898	15/18639	0.133333333333333	1.30937829293994	0.460742930905156	0.745390396071693
GO:0015108	chloride transmembrane transporter activity	13/1898	121/18639	0.107438016528926	1.05507755009623	0.462734519152419	0.747633811336457
GO:0052689	carboxylic ester hydrolase activity	10/1898	92/18639	0.108695652173913	1.06742795620104	0.463625909459276	0.748096115002174
GO:0005254	chloride channel activity	9/1898	83/18639	0.108433734939759	1.06485584064392	0.473686197302203	0.760366711556673
GO:0003707	nuclear steroid receptor activity	3/1898	25/18639	0.12	1.17844046364594	0.475365558487264	0.760366711556673
GO:0017025	TBP-class protein binding	3/1898	25/18639	0.12	1.17844046364594	0.475365558487264	0.760366711556673
GO:0017056	structural constituent of nuclear pore	3/1898	25/18639	0.12	1.17844046364594	0.475365558487264	0.760366711556673
GO:0047617	fatty acyl-CoA hydrolase activity	3/1898	25/18639	0.12	1.17844046364594	0.475365558487264	0.760366711556673
GO:0003925	G protein activity	6/1898	54/18639	0.111111111111111	1.09114857744995	0.475536786434715	0.760366711556673
GO:0015485	cholesterol binding	6/1898	54/18639	0.111111111111111	1.09114857744995	0.475536786434715	0.760366711556673
GO:0004536	DNA nuclease activity	7/1898	64/18639	0.109375	1.07409938092729	0.480623783412817	0.767507747155352
GO:0005154	epidermal growth factor receptor binding	4/1898	35/18639	0.114285714285714	1.12232425109137	0.483670159841823	0.771375893631604
GO:0004527	exonuclease activity	9/1898	84/18639	0.107142857142857	1.05217898539816	0.488468587722626	0.77802470931078
GO:0015562	efflux transmembrane transporter activity	2/1898	16/18639	0.125	1.22754214963119	0.495342291502472	0.782919529791631
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	2/1898	16/18639	0.125	1.22754214963119	0.495342291502472	0.782919529791631
GO:0017070	U6 snRNA binding	2/1898	16/18639	0.125	1.22754214963119	0.495342291502472	0.782919529791631
GO:0022858	alanine transmembrane transporter activity	2/1898	16/18639	0.125	1.22754214963119	0.495342291502472	0.782919529791631
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	2/1898	16/18639	0.125	1.22754214963119	0.495342291502472	0.782919529791631
GO:0140328	floppase activity	2/1898	16/18639	0.125	1.22754214963119	0.495342291502472	0.782919529791631
GO:0160215	deacylase activity	7/1898	65/18639	0.107692307692308	1.05757477506687	0.49743567045704	0.785224123480078
GO:0004112	cyclic-nucleotide phosphodiesterase activity	3/1898	26/18639	0.115384615384615	1.13311583042879	0.502176818448862	0.787678359902021
GO:0005227	calcium-activated cation channel activity	3/1898	26/18639	0.115384615384615	1.13311583042879	0.502176818448862	0.787678359902021
GO:0008198	ferrous iron binding	3/1898	26/18639	0.115384615384615	1.13311583042879	0.502176818448862	0.787678359902021
GO:0016289	acyl-CoA hydrolase activity	3/1898	26/18639	0.115384615384615	1.13311583042879	0.502176818448862	0.787678359902021
GO:0043548	phosphatidylinositol 3-kinase binding	3/1898	26/18639	0.115384615384615	1.13311583042879	0.502176818448862	0.787678359902021
GO:0035401	histone H3Y41 kinase activity	12/1898	115/18639	0.104347826086957	1.02473083795299	0.509610125544936	0.797314069839925
GO:0140801	histone H2AXY142 kinase activity	12/1898	115/18639	0.104347826086957	1.02473083795299	0.509610125544936	0.797314069839925
GO:0016779	nucleotidyltransferase activity	14/1898	136/18639	0.102941176470588	1.01091706440216	0.524661382787221	0.808334566114658
GO:0001671	ATPase activator activity	3/1898	27/18639	0.111111111111111	1.09114857744995	0.528265208160773	0.808334566114658
GO:0008266	poly(U) RNA binding	3/1898	27/18639	0.111111111111111	1.09114857744995	0.528265208160773	0.808334566114658
GO:0008320	protein transmembrane transporter activity	3/1898	27/18639	0.111111111111111	1.09114857744995	0.528265208160773	0.808334566114658
GO:0004549	tRNA-specific ribonuclease activity	2/1898	17/18639	0.117647058823529	1.15533378788818	0.528490892964395	0.808334566114658
GO:0004550	nucleoside diphosphate kinase activity	2/1898	17/18639	0.117647058823529	1.15533378788818	0.528490892964395	0.808334566114658
GO:0004659	prenyltransferase activity	2/1898	17/18639	0.117647058823529	1.15533378788818	0.528490892964395	0.808334566114658
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	2/1898	17/18639	0.117647058823529	1.15533378788818	0.528490892964395	0.808334566114658
GO:0005092	GDP-dissociation inhibitor activity	2/1898	17/18639	0.117647058823529	1.15533378788818	0.528490892964395	0.808334566114658
GO:0008569	minus-end-directed microtubule motor activity	2/1898	17/18639	0.117647058823529	1.15533378788818	0.528490892964395	0.808334566114658
GO:0016018	cyclosporin A binding	2/1898	17/18639	0.117647058823529	1.15533378788818	0.528490892964395	0.808334566114658
GO:0030169	low-density lipoprotein particle binding	2/1898	17/18639	0.117647058823529	1.15533378788818	0.528490892964395	0.808334566114658
GO:0036041	long-chain fatty acid binding	2/1898	17/18639	0.117647058823529	1.15533378788818	0.528490892964395	0.808334566114658
GO:0038191	neuropilin binding	2/1898	17/18639	0.117647058823529	1.15533378788818	0.528490892964395	0.808334566114658
GO:0048038	quinone binding	2/1898	17/18639	0.117647058823529	1.15533378788818	0.528490892964395	0.808334566114658
GO:0019213	deacetylase activity	4/1898	37/18639	0.108108108108108	1.06165807535671	0.528540077879091	0.808334566114658
GO:0030551	cyclic nucleotide binding	4/1898	37/18639	0.108108108108108	1.06165807535671	0.528540077879091	0.808334566114658
GO:0001784	phosphotyrosine residue binding	5/1898	47/18639	0.106382978723404	1.04471672309038	0.529079825232005	0.808334566114658
GO:0140359	ABC-type transporter activity	5/1898	47/18639	0.106382978723404	1.04471672309038	0.529079825232005	0.808334566114658
GO:0061134	peptidase regulator activity	23/1898	226/18639	0.101769911504425	0.999414847487341	0.53388452842707	0.814668243377603
GO:0003777	microtubule motor activity	7/1898	68/18639	0.102941176470588	1.01091706440216	0.546722800299906	0.833229816486663
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	5/1898	48/18639	0.104166666666667	1.02295179135933	0.548385065176128	0.834287246141673
GO:0016247	channel regulator activity	17/1898	168/18639	0.101190476190476	0.993724597320488	0.548766610932993	0.834287246141673
GO:0051019	mitogen-activated protein kinase binding	3/1898	28/18639	0.107142857142857	1.05217898539816	0.553571955403367	0.840558890514204
GO:0008409	5'-3' exonuclease activity	2/1898	18/18639	0.111111111111111	1.09114857744995	0.560125316082501	0.843083895979973
GO:0015172	acidic amino acid transmembrane transporter activity	2/1898	18/18639	0.111111111111111	1.09114857744995	0.560125316082501	0.843083895979973
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	2/1898	18/18639	0.111111111111111	1.09114857744995	0.560125316082501	0.843083895979973
GO:0016854	racemase and epimerase activity	2/1898	18/18639	0.111111111111111	1.09114857744995	0.560125316082501	0.843083895979973
GO:0017075	syntaxin-1 binding	2/1898	18/18639	0.111111111111111	1.09114857744995	0.560125316082501	0.843083895979973
GO:0022851	GABA-gated chloride ion channel activity	2/1898	18/18639	0.111111111111111	1.09114857744995	0.560125316082501	0.843083895979973
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	2/1898	18/18639	0.111111111111111	1.09114857744995	0.560125316082501	0.843083895979973
GO:0042277	peptide binding	25/1898	249/18639	0.100401606425703	0.985977630225856	0.561112183572544	0.843083895979973
GO:0033293	monocarboxylic acid binding	8/1898	79/18639	0.10126582278481	0.994464526283496	0.561373823941357	0.843083895979973
GO:0045309	protein phosphorylated amino acid binding	6/1898	59/18639	0.101694915254237	0.998678359021986	0.564575117020355	0.846862675530533
GO:0141108	transporter regulator activity	17/1898	170/18639	0.1	0.982033719704953	0.56917262460767	0.85196637441468
GO:0099106	ion channel regulator activity	16/1898	160/18639	0.1	0.982033719704953	0.569356169309487	0.85196637441468
GO:0000217	DNA secondary structure binding	4/1898	39/18639	0.102564102564103	1.00721407149226	0.571411867816984	0.854008547305674
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	3/1898	29/18639	0.103448275862069	1.01589695141892	0.578050391302322	0.860305020555015
GO:0051861	glycolipid binding	3/1898	29/18639	0.103448275862069	1.01589695141892	0.578050391302322	0.860305020555015
GO:0099604	ligand-gated calcium channel activity	3/1898	29/18639	0.103448275862069	1.01589695141892	0.578050391302322	0.860305020555015
GO:0008028	monocarboxylic acid transmembrane transporter activity	7/1898	70/18639	0.1	0.982033719704953	0.578408957994512	0.860305020555015
GO:0004540	RNA nuclease activity	12/1898	121/18639	0.0991735537190083	0.973917738550366	0.583037525979872	0.86614709388356
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	2/1898	19/18639	0.105263157894737	1.03371970495258	0.590210081479273	0.869004114296044
GO:0004890	GABA-A receptor activity	2/1898	19/18639	0.105263157894737	1.03371970495258	0.590210081479273	0.869004114296044
GO:0008574	plus-end-directed microtubule motor activity	2/1898	19/18639	0.105263157894737	1.03371970495258	0.590210081479273	0.869004114296044
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	2/1898	19/18639	0.105263157894737	1.03371970495258	0.590210081479273	0.869004114296044
GO:0043395	heparan sulfate proteoglycan binding	2/1898	19/18639	0.105263157894737	1.03371970495258	0.590210081479273	0.869004114296044
GO:0046527	glucosyltransferase activity	2/1898	19/18639	0.105263157894737	1.03371970495258	0.590210081479273	0.869004114296044
GO:0097001	ceramide binding	2/1898	19/18639	0.105263157894737	1.03371970495258	0.590210081479273	0.869004114296044
GO:0030971	receptor tyrosine kinase binding	8/1898	81/18639	0.0987654320987654	0.969909846622175	0.59058532039537	0.869004114296044
GO:0015171	amino acid transmembrane transporter activity	10/1898	102/18639	0.0980392156862745	0.962778156573483	0.598846576788263	0.877990258095591
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	3/1898	30/18639	0.1	0.982033719704953	0.601664845151267	0.877990258095591
GO:0008187	poly-pyrimidine tract binding	3/1898	30/18639	0.1	0.982033719704953	0.601664845151267	0.877990258095591
GO:0022839	monoatomic ion-gated channel activity	3/1898	30/18639	0.1	0.982033719704953	0.601664845151267	0.877990258095591
GO:0031210	phosphatidylcholine binding	3/1898	30/18639	0.1	0.982033719704953	0.601664845151267	0.877990258095591
GO:0033612	receptor serine/threonine kinase binding	3/1898	30/18639	0.1	0.982033719704953	0.601664845151267	0.877990258095591
GO:0051721	protein phosphatase 2A binding	3/1898	30/18639	0.1	0.982033719704953	0.601664845151267	0.877990258095591
GO:0030544	Hsp70 protein binding	5/1898	51/18639	0.0980392156862745	0.962778156573483	0.603861530537729	0.8801566647932
GO:0005253	monoatomic anion channel activity	10/1898	103/18639	0.0970873786407767	0.953430795830051	0.611498027238176	0.889927249270373
GO:0001530	lipopolysaccharide binding	4/1898	41/18639	0.0975609756097561	0.958081677760929	0.612004985339658	0.889927249270373
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	2/1898	20/18639	0.1	0.982033719704953	0.618732622096938	0.894318611190219
GO:0016004	phospholipase activator activity	2/1898	20/18639	0.1	0.982033719704953	0.618732622096938	0.894318611190219
GO:0016505	peptidase activator activity involved in apoptotic process	2/1898	20/18639	0.1	0.982033719704953	0.618732622096938	0.894318611190219
GO:0043024	ribosomal small subunit binding	2/1898	20/18639	0.1	0.982033719704953	0.618732622096938	0.894318611190219
GO:0052745	inositol phosphate phosphatase activity	2/1898	20/18639	0.1	0.982033719704953	0.618732622096938	0.894318611190219
GO:0004521	RNA endonuclease activity	7/1898	73/18639	0.0958904109589041	0.941676169580091	0.623826225226144	0.894318611190219
GO:0005164	tumor necrosis factor receptor binding	3/1898	31/18639	0.0967741935483871	0.950355212617696	0.624389562547877	0.894318611190219
GO:0005452	solute:inorganic anion antiporter activity	3/1898	31/18639	0.0967741935483871	0.950355212617696	0.624389562547877	0.894318611190219
GO:0016411	acylglycerol O-acyltransferase activity	3/1898	31/18639	0.0967741935483871	0.950355212617696	0.624389562547877	0.894318611190219
GO:0008307	structural constituent of muscle	4/1898	42/18639	0.0952380952380952	0.935270209242812	0.631384256575893	0.894318611190219
GO:0016859	cis-trans isomerase activity	4/1898	42/18639	0.0952380952380952	0.935270209242812	0.631384256575893	0.894318611190219
GO:0004860	protein kinase inhibitor activity	8/1898	84/18639	0.0952380952380952	0.935270209242812	0.632540703948805	0.894318611190219
GO:0008146	sulfotransferase activity	5/1898	53/18639	0.0943396226415094	0.926446905382031	0.638590350276566	0.894318611190219
GO:0015085	calcium ion transmembrane transporter activity	14/1898	147/18639	0.0952380952380952	0.935270209242812	0.64481075364456	0.894318611190219
GO:0009931	calcium-dependent protein serine/threonine kinase activity	2/1898	21/18639	0.0952380952380952	0.935270209242812	0.645698989036721	0.894318611190219
GO:0036122	BMP binding	2/1898	21/18639	0.0952380952380952	0.935270209242812	0.645698989036721	0.894318611190219
GO:0022884	macromolecule transmembrane transporter activity	3/1898	32/18639	0.09375	0.920656612223393	0.646207661284304	0.894318611190219
GO:0031369	translation initiation factor binding	3/1898	32/18639	0.09375	0.920656612223393	0.646207661284304	0.894318611190219
GO:0043425	bHLH transcription factor binding	3/1898	32/18639	0.09375	0.920656612223393	0.646207661284304	0.894318611190219
GO:0120015	sterol transfer activity	3/1898	32/18639	0.09375	0.920656612223393	0.646207661284304	0.894318611190219
GO:0005201	extracellular matrix structural constituent	16/1898	168/18639	0.0952380952380952	0.935270209242812	0.649302528398027	0.894318611190219
GO:0004519	endonuclease activity	12/1898	127/18639	0.094488188976378	0.927905876886569	0.651350286962199	0.894318611190219
GO:0019003	GDP binding	7/1898	75/18639	0.0933333333333333	0.916564805057956	0.652537736453657	0.894318611190219
GO:0000182	rDNA binding	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0004445	inositol-polyphosphate 5-phosphatase activity	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0004935	adrenergic receptor activity	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0004955	prostaglandin receptor activity	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0008140	cAMP response element binding protein binding	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0008190	eukaryotic initiation factor 4E binding	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0008641	ubiquitin-like modifier activating enzyme activity	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0015187	glycine transmembrane transporter activity	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0015203	polyamine transmembrane transporter activity	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0016427	tRNA (cytidine) methyltransferase activity	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0019531	oxalate transmembrane transporter activity	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0031419	cobalamin binding	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0031996	thioesterase binding	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0032052	bile acid binding	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0032356	oxidized DNA binding	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0033204	ribonuclease P RNA binding	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0035256	G protein-coupled glutamate receptor binding	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0035374	chondroitin sulfate binding	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0043121	neurotrophin binding	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0043208	glycosphingolipid binding	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0050308	sugar-phosphatase activity	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0050815	phosphoserine residue binding	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0051378	serotonin binding	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0070513	death domain binding	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0097177	mitochondrial ribosome binding	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0099122	RNA polymerase II C-terminal domain binding	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0140135	mechanosensitive monoatomic cation channel activity	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:1905394	retromer complex binding	1/1898	10/18639	0.1	0.982033719704953	0.658438459695064	0.894318611190219
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	3/1898	33/18639	0.0909090909090909	0.892757927004502	0.667110135469041	0.901461750992055
GO:0019956	chemokine binding	3/1898	33/18639	0.0909090909090909	0.892757927004502	0.667110135469041	0.901461750992055
GO:0030020	extracellular matrix structural constituent conferring tensile strength	4/1898	44/18639	0.0909090909090909	0.892757927004502	0.668226772660652	0.901461750992055
GO:0004407	histone deacetylase activity	2/1898	22/18639	0.0909090909090909	0.892757927004502	0.671130193643305	0.901461750992055
GO:0005243	gap junction channel activity	2/1898	22/18639	0.0909090909090909	0.892757927004502	0.671130193643305	0.901461750992055
GO:0015377	chloride:monoatomic cation symporter activity	2/1898	22/18639	0.0909090909090909	0.892757927004502	0.671130193643305	0.901461750992055
GO:0031683	G-protein beta/gamma-subunit complex binding	2/1898	22/18639	0.0909090909090909	0.892757927004502	0.671130193643305	0.901461750992055
GO:0033558	protein lysine deacetylase activity	2/1898	22/18639	0.0909090909090909	0.892757927004502	0.671130193643305	0.901461750992055
GO:0070034	telomerase RNA binding	2/1898	22/18639	0.0909090909090909	0.892757927004502	0.671130193643305	0.901461750992055
GO:0140035	ubiquitin-like protein reader activity	2/1898	22/18639	0.0909090909090909	0.892757927004502	0.671130193643305	0.901461750992055
GO:0004715	non-membrane spanning protein tyrosine kinase activity	4/1898	45/18639	0.0888888888888889	0.872918861959958	0.685670778920049	0.901461750992055
GO:0008173	RNA methyltransferase activity	6/1898	67/18639	0.0895522388059701	0.879433181825331	0.689674245253512	0.901461750992055
GO:0000099	sulfur amino acid transmembrane transporter activity	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0004016	adenylate cyclase activity	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0004143	ATP-dependent diacylglycerol kinase activity	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0004523	RNA-DNA hybrid ribonuclease activity	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0004954	prostanoid receptor activity	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0005114	type II transforming growth factor beta receptor binding	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0005225	volume-sensitive anion channel activity	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0005536	D-glucose binding	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0008526	phosphatidylinositol transfer activity	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0010854	adenylate cyclase regulator activity	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0015173	aromatic amino acid transmembrane transporter activity	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0019203	carbohydrate phosphatase activity	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0019206	nucleoside kinase activity	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0043522	leucine zipper domain binding	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0045294	alpha-catenin binding	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0048407	platelet-derived growth factor binding	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0070990	snRNP binding	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0140031	phosphorylation-dependent protein binding	1/1898	11/18639	0.0909090909090909	0.892757927004502	0.693238170012245	0.901461750992055
GO:0003887	DNA-directed DNA polymerase activity	2/1898	23/18639	0.0869565217391304	0.853942364960828	0.695059100886269	0.901461750992055
GO:0005283	amino acid:sodium symporter activity	2/1898	23/18639	0.0869565217391304	0.853942364960828	0.695059100886269	0.901461750992055
GO:0016917	GABA receptor activity	2/1898	23/18639	0.0869565217391304	0.853942364960828	0.695059100886269	0.901461750992055
GO:0031681	G-protein beta-subunit binding	2/1898	23/18639	0.0869565217391304	0.853942364960828	0.695059100886269	0.901461750992055
GO:0099186	structural constituent of postsynapse	2/1898	23/18639	0.0869565217391304	0.853942364960828	0.695059100886269	0.901461750992055
GO:0004180	carboxypeptidase activity	4/1898	46/18639	0.0869565217391304	0.853942364960828	0.702457006305146	0.90451980543034
GO:0005343	organic acid:sodium symporter activity	3/1898	35/18639	0.0857142857142857	0.841743188318531	0.706165985937908	0.90451980543034
GO:0034061	DNA polymerase activity	3/1898	35/18639	0.0857142857142857	0.841743188318531	0.706165985937908	0.90451980543034
GO:0043015	gamma-tubulin binding	3/1898	35/18639	0.0857142857142857	0.841743188318531	0.706165985937908	0.90451980543034
GO:0015081	sodium ion transmembrane transporter activity	15/1898	164/18639	0.0914634146341463	0.898201572900871	0.707851644337008	0.90451980543034
GO:0019210	kinase inhibitor activity	8/1898	90/18639	0.0888888888888889	0.872918861959958	0.708783529710259	0.90451980543034
GO:0005315	phosphate transmembrane transporter activity	2/1898	24/18639	0.0833333333333333	0.81836143308746	0.71752779978007	0.90451980543034
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	2/1898	24/18639	0.0833333333333333	0.81836143308746	0.71752779978007	0.90451980543034
GO:0035035	histone acetyltransferase binding	2/1898	24/18639	0.0833333333333333	0.81836143308746	0.71752779978007	0.90451980543034
GO:0060229	lipase activator activity	2/1898	24/18639	0.0833333333333333	0.81836143308746	0.71752779978007	0.90451980543034
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	2/1898	24/18639	0.0833333333333333	0.81836143308746	0.71752779978007	0.90451980543034
GO:0140612	DNA damage sensor activity	2/1898	24/18639	0.0833333333333333	0.81836143308746	0.71752779978007	0.90451980543034
GO:0000049	tRNA binding	7/1898	80/18639	0.0875	0.859279504741833	0.718306584524373	0.90451980543034
GO:0048306	calcium-dependent protein binding	7/1898	80/18639	0.0875	0.859279504741833	0.718306584524373	0.90451980543034
GO:0043495	protein-membrane adaptor activity	4/1898	47/18639	0.0851063829787234	0.8357733784723	0.718585116172415	0.90451980543034
GO:0099095	ligand-gated monoatomic anion channel activity	4/1898	47/18639	0.0851063829787234	0.8357733784723	0.718585116172415	0.90451980543034
GO:0005484	SNAP receptor activity	3/1898	36/18639	0.0833333333333333	0.81836143308746	0.724332571609804	0.90451980543034
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	3/1898	36/18639	0.0833333333333333	0.81836143308746	0.724332571609804	0.90451980543034
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	3/1898	36/18639	0.0833333333333333	0.81836143308746	0.724332571609804	0.90451980543034
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	3/1898	36/18639	0.0833333333333333	0.81836143308746	0.724332571609804	0.90451980543034
GO:0003720	telomerase activity	1/1898	12/18639	0.0833333333333333	0.81836143308746	0.724494018912651	0.90451980543034
GO:0004000	adenosine deaminase activity	1/1898	12/18639	0.0833333333333333	0.81836143308746	0.724494018912651	0.90451980543034
GO:0005436	sodium:phosphate symporter activity	1/1898	12/18639	0.0833333333333333	0.81836143308746	0.724494018912651	0.90451980543034
GO:0008179	adenylate cyclase binding	1/1898	12/18639	0.0833333333333333	0.81836143308746	0.724494018912651	0.90451980543034
GO:0008603	cAMP-dependent protein kinase regulator activity	1/1898	12/18639	0.0833333333333333	0.81836143308746	0.724494018912651	0.90451980543034
GO:0010853	cyclase activator activity	1/1898	12/18639	0.0833333333333333	0.81836143308746	0.724494018912651	0.90451980543034
GO:0015269	calcium-activated potassium channel activity	1/1898	12/18639	0.0833333333333333	0.81836143308746	0.724494018912651	0.90451980543034
GO:0016208	AMP binding	1/1898	12/18639	0.0833333333333333	0.81836143308746	0.724494018912651	0.90451980543034
GO:0016801	hydrolase activity, acting on ether bonds	1/1898	12/18639	0.0833333333333333	0.81836143308746	0.724494018912651	0.90451980543034
GO:0016803	ether hydrolase activity	1/1898	12/18639	0.0833333333333333	0.81836143308746	0.724494018912651	0.90451980543034
GO:0016840	carbon-nitrogen lyase activity	1/1898	12/18639	0.0833333333333333	0.81836143308746	0.724494018912651	0.90451980543034
GO:0035251	UDP-glucosyltransferase activity	1/1898	12/18639	0.0833333333333333	0.81836143308746	0.724494018912651	0.90451980543034
GO:0070679	inositol 1,4,5 trisphosphate binding	1/1898	12/18639	0.0833333333333333	0.81836143308746	0.724494018912651	0.90451980543034
GO:0097371	MDM2/MDM4 family protein binding	1/1898	12/18639	0.0833333333333333	0.81836143308746	0.724494018912651	0.90451980543034
GO:0140829	bicarbonate:monoatomic anion antiporter activity	1/1898	12/18639	0.0833333333333333	0.81836143308746	0.724494018912651	0.90451980543034
GO:0140900	chloride:bicarbonate antiporter activity	1/1898	12/18639	0.0833333333333333	0.81836143308746	0.724494018912651	0.90451980543034
GO:1990459	transferrin receptor binding	1/1898	12/18639	0.0833333333333333	0.81836143308746	0.724494018912651	0.90451980543034
GO:0070888	E-box binding	5/1898	59/18639	0.0847457627118644	0.832231965851655	0.730810300335902	0.911484895272629
GO:0003730	mRNA 3'-UTR binding	24/1898	262/18639	0.0916030534351145	0.89957287301217	0.738481514576641	0.912828729934842
GO:0015271	outward rectifier potassium channel activity	2/1898	25/18639	0.08	0.785626975763962	0.738585385979445	0.912828729934842
GO:0015296	monoatomic anion:monoatomic cation symporter activity	2/1898	25/18639	0.08	0.785626975763962	0.738585385979445	0.912828729934842
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	2/1898	25/18639	0.08	0.785626975763962	0.738585385979445	0.912828729934842
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	2/1898	25/18639	0.08	0.785626975763962	0.738585385979445	0.912828729934842
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	2/1898	25/18639	0.08	0.785626975763962	0.738585385979445	0.912828729934842
GO:0120020	cholesterol transfer activity	2/1898	25/18639	0.08	0.785626975763962	0.738585385979445	0.912828729934842
GO:0022829	wide pore channel activity	3/1898	37/18639	0.0810810810810811	0.796243556517529	0.741608379880161	0.912828729934842
GO:0140098	catalytic activity, acting on RNA	36/1898	387/18639	0.0930232558139535	0.913519739260421	0.742664893452646	0.912828729934842
GO:0002161	aminoacyl-tRNA editing activity	1/1898	13/18639	0.0769230769230769	0.755410553619194	0.752566727996443	0.912828729934842
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/1898	13/18639	0.0769230769230769	0.755410553619194	0.752566727996443	0.912828729934842
GO:0003964	RNA-directed DNA polymerase activity	1/1898	13/18639	0.0769230769230769	0.755410553619194	0.752566727996443	0.912828729934842
GO:0005172	vascular endothelial growth factor receptor binding	1/1898	13/18639	0.0769230769230769	0.755410553619194	0.752566727996443	0.912828729934842
GO:0008417	fucosyltransferase activity	1/1898	13/18639	0.0769230769230769	0.755410553619194	0.752566727996443	0.912828729934842
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/1898	13/18639	0.0769230769230769	0.755410553619194	0.752566727996443	0.912828729934842
GO:0019855	calcium channel inhibitor activity	1/1898	13/18639	0.0769230769230769	0.755410553619194	0.752566727996443	0.912828729934842
GO:0030955	potassium ion binding	1/1898	13/18639	0.0769230769230769	0.755410553619194	0.752566727996443	0.912828729934842
GO:0031432	titin binding	1/1898	13/18639	0.0769230769230769	0.755410553619194	0.752566727996443	0.912828729934842
GO:0035673	oligopeptide transmembrane transporter activity	1/1898	13/18639	0.0769230769230769	0.755410553619194	0.752566727996443	0.912828729934842
GO:0039706	co-receptor binding	1/1898	13/18639	0.0769230769230769	0.755410553619194	0.752566727996443	0.912828729934842
GO:0043560	insulin receptor substrate binding	1/1898	13/18639	0.0769230769230769	0.755410553619194	0.752566727996443	0.912828729934842
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/1898	13/18639	0.0769230769230769	0.755410553619194	0.752566727996443	0.912828729934842
GO:0045159	myosin II binding	1/1898	13/18639	0.0769230769230769	0.755410553619194	0.752566727996443	0.912828729934842
GO:0140333	glycerophospholipid flippase activity	1/1898	13/18639	0.0769230769230769	0.755410553619194	0.752566727996443	0.912828729934842
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/1898	13/18639	0.0769230769230769	0.755410553619194	0.752566727996443	0.912828729934842
GO:0140666	annealing activity	1/1898	13/18639	0.0769230769230769	0.755410553619194	0.752566727996443	0.912828729934842
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/1898	13/18639	0.0769230769230769	0.755410553619194	0.752566727996443	0.912828729934842
GO:1901338	catecholamine binding	1/1898	13/18639	0.0769230769230769	0.755410553619194	0.752566727996443	0.912828729934842
GO:0019905	syntaxin binding	5/1898	61/18639	0.0819672131147541	0.804945671889305	0.757443277059196	0.915275019068597
GO:0004529	DNA exonuclease activity	2/1898	26/18639	0.0769230769230769	0.755410553619194	0.758286099940326	0.915275019068597
GO:0008157	protein phosphatase 1 binding	2/1898	26/18639	0.0769230769230769	0.755410553619194	0.758286099940326	0.915275019068597
GO:0030247	polysaccharide binding	2/1898	26/18639	0.0769230769230769	0.755410553619194	0.758286099940326	0.915275019068597
GO:0120014	phospholipid transfer activity	2/1898	26/18639	0.0769230769230769	0.755410553619194	0.758286099940326	0.915275019068597
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	3/1898	39/18639	0.0769230769230769	0.755410553619194	0.773560831978082	0.927036137478044
GO:0005272	sodium channel activity	4/1898	51/18639	0.0784313725490196	0.770222525258786	0.776610490902207	0.927036137478044
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	2/1898	27/18639	0.0740740740740741	0.727432384966631	0.776687771282691	0.927036137478044
GO:0004705	JUN kinase activity	1/1898	14/18639	0.0714285714285714	0.701452656932109	0.777780319227129	0.927036137478044
GO:0005161	platelet-derived growth factor receptor binding	1/1898	14/18639	0.0714285714285714	0.701452656932109	0.777780319227129	0.927036137478044
GO:0008174	mRNA methyltransferase activity	1/1898	14/18639	0.0714285714285714	0.701452656932109	0.777780319227129	0.927036137478044
GO:0008494	translation activator activity	1/1898	14/18639	0.0714285714285714	0.701452656932109	0.777780319227129	0.927036137478044
GO:0015386	potassium:proton antiporter activity	1/1898	14/18639	0.0714285714285714	0.701452656932109	0.777780319227129	0.927036137478044
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/1898	14/18639	0.0714285714285714	0.701452656932109	0.777780319227129	0.927036137478044
GO:0034236	protein kinase A catalytic subunit binding	1/1898	14/18639	0.0714285714285714	0.701452656932109	0.777780319227129	0.927036137478044
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	1/1898	14/18639	0.0714285714285714	0.701452656932109	0.777780319227129	0.927036137478044
GO:0042043	neurexin family protein binding	1/1898	14/18639	0.0714285714285714	0.701452656932109	0.777780319227129	0.927036137478044
GO:1901612	cardiolipin binding	1/1898	14/18639	0.0714285714285714	0.701452656932109	0.777780319227129	0.927036137478044
GO:0061135	endopeptidase regulator activity	16/1898	184/18639	0.0869565217391304	0.853942364960828	0.782651147362465	0.931676565566695
GO:0016298	lipase activity	11/1898	130/18639	0.0846153846153846	0.830951608981114	0.783181190634139	0.931676565566695
GO:0004857	enzyme inhibitor activity	38/1898	416/18639	0.0913461538461538	0.897050032422793	0.785095878596686	0.933056255716831
GO:0004620	phospholipase activity	9/1898	109/18639	0.0825688073394495	0.810853530031612	0.79182379308783	0.936717665575326
GO:0003774	cytoskeletal motor activity	13/1898	153/18639	0.0849673202614379	0.834407735697019	0.792735291732556	0.936717665575326
GO:0046625	sphingolipid binding	2/1898	28/18639	0.0714285714285714	0.701452656932109	0.793850526350331	0.936717665575326
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	2/1898	28/18639	0.0714285714285714	0.701452656932109	0.793850526350331	0.936717665575326
GO:0004089	carbonate dehydratase activity	1/1898	15/18639	0.0666666666666667	0.654689146469968	0.800425846964413	0.936717665575326
GO:0004953	icosanoid receptor activity	1/1898	15/18639	0.0666666666666667	0.654689146469968	0.800425846964413	0.936717665575326
GO:0008020	G protein-coupled photoreceptor activity	1/1898	15/18639	0.0666666666666667	0.654689146469968	0.800425846964413	0.936717665575326
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/1898	15/18639	0.0666666666666667	0.654689146469968	0.800425846964413	0.936717665575326
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	1/1898	15/18639	0.0666666666666667	0.654689146469968	0.800425846964413	0.936717665575326
GO:0030553	cGMP binding	1/1898	15/18639	0.0666666666666667	0.654689146469968	0.800425846964413	0.936717665575326
GO:0031005	filamin binding	1/1898	15/18639	0.0666666666666667	0.654689146469968	0.800425846964413	0.936717665575326
GO:0034483	heparan sulfate sulfotransferase activity	1/1898	15/18639	0.0666666666666667	0.654689146469968	0.800425846964413	0.936717665575326
GO:0050780	dopamine receptor binding	1/1898	15/18639	0.0666666666666667	0.654689146469968	0.800425846964413	0.936717665575326
GO:0140161	monocarboxylate:sodium symporter activity	1/1898	15/18639	0.0666666666666667	0.654689146469968	0.800425846964413	0.936717665575326
GO:0140776	protein-containing complex destabilizing activity	1/1898	15/18639	0.0666666666666667	0.654689146469968	0.800425846964413	0.936717665575326
GO:0005246	calcium channel regulator activity	4/1898	53/18639	0.0754716981132075	0.741157524305625	0.801861773329204	0.936717665575326
GO:0005544	calcium-dependent phospholipid binding	4/1898	53/18639	0.0754716981132075	0.741157524305625	0.801861773329204	0.936717665575326
GO:0016251	RNA polymerase II general transcription initiation factor activity	4/1898	53/18639	0.0754716981132075	0.741157524305625	0.801861773329204	0.936717665575326
GO:0017171	serine hydrolase activity	17/1898	198/18639	0.0858585858585859	0.843160264393141	0.80453937292582	0.936717665575326
GO:0120013	lipid transfer activity	5/1898	65/18639	0.0769230769230769	0.755410553619194	0.804674835980415	0.936717665575326
GO:0004518	nuclease activity	18/1898	209/18639	0.0861244019138756	0.845770667688476	0.805991630646278	0.936717665575326
GO:0004181	metallocarboxypeptidase activity	2/1898	29/18639	0.0689655172413793	0.677264634279278	0.809835721539073	0.936717665575326
GO:0004629	phospholipase C activity	2/1898	29/18639	0.0689655172413793	0.677264634279278	0.809835721539073	0.936717665575326
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	2/1898	29/18639	0.0689655172413793	0.677264634279278	0.809835721539073	0.936717665575326
GO:0005416	amino acid:monoatomic cation symporter activity	2/1898	29/18639	0.0689655172413793	0.677264634279278	0.809835721539073	0.936717665575326
GO:0097472	cyclin-dependent protein kinase activity	2/1898	29/18639	0.0689655172413793	0.677264634279278	0.809835721539073	0.936717665575326
GO:0017069	snRNA binding	4/1898	54/18639	0.0740740740740741	0.727432384966631	0.813592437672666	0.936717665575326
GO:0005319	lipid transporter activity	15/1898	178/18639	0.0842696629213483	0.827556505369342	0.815319991141769	0.936717665575326
GO:0043022	ribosome binding	9/1898	112/18639	0.0803571428571429	0.789134239048623	0.817144928863166	0.936717665575326
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	1/1898	16/18639	0.0625	0.613771074815595	0.820764750661875	0.936717665575326
GO:0004707	MAP kinase activity	1/1898	16/18639	0.0625	0.613771074815595	0.820764750661875	0.936717665575326
GO:0005159	insulin-like growth factor receptor binding	1/1898	16/18639	0.0625	0.613771074815595	0.820764750661875	0.936717665575326
GO:0005521	lamin binding	1/1898	16/18639	0.0625	0.613771074815595	0.820764750661875	0.936717665575326
GO:0008142	oxysterol binding	1/1898	16/18639	0.0625	0.613771074815595	0.820764750661875	0.936717665575326
GO:0008296	3'-5'-DNA exonuclease activity	1/1898	16/18639	0.0625	0.613771074815595	0.820764750661875	0.936717665575326
GO:0015378	sodium:chloride symporter activity	1/1898	16/18639	0.0625	0.613771074815595	0.820764750661875	0.936717665575326
GO:0015385	sodium:proton antiporter activity	1/1898	16/18639	0.0625	0.613771074815595	0.820764750661875	0.936717665575326
GO:0016722	oxidoreductase activity, acting on metal ions	1/1898	16/18639	0.0625	0.613771074815595	0.820764750661875	0.936717665575326
GO:0022841	potassium ion leak channel activity	1/1898	16/18639	0.0625	0.613771074815595	0.820764750661875	0.936717665575326
GO:0030275	LRR domain binding	1/1898	16/18639	0.0625	0.613771074815595	0.820764750661875	0.936717665575326
GO:0031435	mitogen-activated protein kinase kinase kinase binding	1/1898	16/18639	0.0625	0.613771074815595	0.820764750661875	0.936717665575326
GO:0043023	ribosomal large subunit binding	1/1898	16/18639	0.0625	0.613771074815595	0.820764750661875	0.936717665575326
GO:0055102	lipase inhibitor activity	1/1898	16/18639	0.0625	0.613771074815595	0.820764750661875	0.936717665575326
GO:0001965	G-protein alpha-subunit binding	2/1898	30/18639	0.0666666666666667	0.654689146469968	0.824705069852487	0.940269166913934
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	5/1898	67/18639	0.0746268656716418	0.732860984854442	0.825398095551471	0.940269166913934
GO:0030414	peptidase inhibitor activity	14/1898	169/18639	0.0828402366863905	0.813519057743748	0.827801980864297	0.941472803409199
GO:0016853	isomerase activity	15/1898	180/18639	0.0833333333333333	0.81836143308746	0.827978104616342	0.941472803409199
GO:0030145	manganese ion binding	5/1898	68/18639	0.0735294117647059	0.722083617430112	0.835071892336868	0.944381289385965
GO:0008327	methyl-CpG binding	2/1898	31/18639	0.0645161290322581	0.633570141745131	0.838519932425219	0.944381289385965
GO:0008429	phosphatidylethanolamine binding	1/1898	17/18639	0.0588235294117647	0.57766689394409	0.839031866767968	0.944381289385965
GO:0008484	sulfuric ester hydrolase activity	1/1898	17/18639	0.0588235294117647	0.57766689394409	0.839031866767968	0.944381289385965
GO:0009881	photoreceptor activity	1/1898	17/18639	0.0588235294117647	0.57766689394409	0.839031866767968	0.944381289385965
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/1898	17/18639	0.0588235294117647	0.57766689394409	0.839031866767968	0.944381289385965
GO:0030548	acetylcholine receptor regulator activity	1/1898	17/18639	0.0588235294117647	0.57766689394409	0.839031866767968	0.944381289385965
GO:0031489	myosin V binding	1/1898	17/18639	0.0588235294117647	0.57766689394409	0.839031866767968	0.944381289385965
GO:0045125	bioactive lipid receptor activity	1/1898	17/18639	0.0588235294117647	0.57766689394409	0.839031866767968	0.944381289385965
GO:0051787	misfolded protein binding	1/1898	17/18639	0.0588235294117647	0.57766689394409	0.839031866767968	0.944381289385965
GO:0070492	oligosaccharide binding	1/1898	17/18639	0.0588235294117647	0.57766689394409	0.839031866767968	0.944381289385965
GO:0043178	alcohol binding	7/1898	92/18639	0.0760869565217391	0.747199569340725	0.839704722520368	0.944381289385965
GO:0008236	serine-type peptidase activity	16/1898	194/18639	0.0824742268041237	0.809924717282435	0.845644345621121	0.950196737443369
GO:0004866	endopeptidase inhibitor activity	13/1898	161/18639	0.0807453416149068	0.792946481749341	0.846742343264144	0.950566336307431
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	2/1898	32/18639	0.0625	0.613771074815595	0.85134075050128	0.950828717793894
GO:0051059	NF-kappaB binding	2/1898	32/18639	0.0625	0.613771074815595	0.85134075050128	0.950828717793894
GO:0000400	four-way junction DNA binding	1/1898	18/18639	0.0555555555555556	0.545574288724974	0.855438134455348	0.950828717793894
GO:0005372	water transmembrane transporter activity	1/1898	18/18639	0.0555555555555556	0.545574288724974	0.855438134455348	0.950828717793894
GO:0015280	ligand-gated sodium channel activity	1/1898	18/18639	0.0555555555555556	0.545574288724974	0.855438134455348	0.950828717793894
GO:0015373	monoatomic anion:sodium symporter activity	1/1898	18/18639	0.0555555555555556	0.545574288724974	0.855438134455348	0.950828717793894
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/1898	18/18639	0.0555555555555556	0.545574288724974	0.855438134455348	0.950828717793894
GO:0050811	GABA receptor binding	1/1898	18/18639	0.0555555555555556	0.545574288724974	0.855438134455348	0.950828717793894
GO:0070628	proteasome binding	1/1898	18/18639	0.0555555555555556	0.545574288724974	0.855438134455348	0.950828717793894
GO:0099602	neurotransmitter receptor regulator activity	1/1898	18/18639	0.0555555555555556	0.545574288724974	0.855438134455348	0.950828717793894
GO:1901611	phosphatidylglycerol binding	1/1898	18/18639	0.0555555555555556	0.545574288724974	0.855438134455348	0.950828717793894
GO:0000149	SNARE binding	8/1898	106/18639	0.0754716981132075	0.741157524305625	0.857661937385503	0.952443984374198
GO:0030291	protein serine/threonine kinase inhibitor activity	3/1898	46/18639	0.0652173913043478	0.640456773720621	0.860699722274608	0.954959476419583
GO:0015459	potassium channel regulator activity	4/1898	59/18639	0.0677966101694915	0.665785572681324	0.863956431851048	0.955418509922679
GO:0031593	polyubiquitin modification-dependent protein binding	4/1898	59/18639	0.0677966101694915	0.665785572681324	0.863956431851048	0.955418509922679
GO:0005262	calcium channel activity	10/1898	131/18639	0.0763358778625954	0.749644060843475	0.869929909623072	0.955418509922679
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	1/1898	19/18639	0.0526315789473684	0.516859852476291	0.870173026287352	0.955418509922679
GO:0005229	intracellularly calcium-gated chloride channel activity	1/1898	19/18639	0.0526315789473684	0.516859852476291	0.870173026287352	0.955418509922679
GO:0016918	retinal binding	1/1898	19/18639	0.0526315789473684	0.516859852476291	0.870173026287352	0.955418509922679
GO:0022821	solute:potassium antiporter activity	1/1898	19/18639	0.0526315789473684	0.516859852476291	0.870173026287352	0.955418509922679
GO:0022840	leak channel activity	1/1898	19/18639	0.0526315789473684	0.516859852476291	0.870173026287352	0.955418509922679
GO:0022842	narrow pore channel activity	1/1898	19/18639	0.0526315789473684	0.516859852476291	0.870173026287352	0.955418509922679
GO:0140036	ubiquitin-modified protein reader activity	1/1898	19/18639	0.0526315789473684	0.516859852476291	0.870173026287352	0.955418509922679
GO:0141147	intracellularly calcium-gated channel activity	1/1898	19/18639	0.0526315789473684	0.516859852476291	0.870173026287352	0.955418509922679
GO:0005504	fatty acid binding	3/1898	47/18639	0.0638297872340425	0.626830033854225	0.870389354508848	0.955418509922679
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	2/1898	34/18639	0.0588235294117647	0.57766689394409	0.874234826726312	0.957938161200108
GO:0030332	cyclin binding	2/1898	34/18639	0.0588235294117647	0.57766689394409	0.874234826726312	0.957938161200108
GO:0001614	purinergic nucleotide receptor activity	1/1898	20/18639	0.05	0.491016859852476	0.883406731771058	0.962866596533534
GO:0001972	retinoic acid binding	1/1898	20/18639	0.05	0.491016859852476	0.883406731771058	0.962866596533534
GO:0010851	cyclase regulator activity	1/1898	20/18639	0.05	0.491016859852476	0.883406731771058	0.962866596533534
GO:0016502	nucleotide receptor activity	1/1898	20/18639	0.05	0.491016859852476	0.883406731771058	0.962866596533534
GO:0030627	pre-mRNA 5'-splice site binding	1/1898	20/18639	0.05	0.491016859852476	0.883406731771058	0.962866596533534
GO:0140664	ATP-dependent DNA damage sensor activity	1/1898	20/18639	0.05	0.491016859852476	0.883406731771058	0.962866596533534
GO:0016229	steroid dehydrogenase activity	2/1898	35/18639	0.0571428571428571	0.561162125545687	0.884420817077124	0.963122581416146
GO:0004869	cysteine-type endopeptidase inhibitor activity	2/1898	36/18639	0.0555555555555556	0.545574288724974	0.893837772692849	0.968985165472864
GO:0001846	opsonin binding	1/1898	21/18639	0.0476190476190476	0.467635104621406	0.895292118907775	0.968985165472864
GO:0005248	voltage-gated sodium channel activity	1/1898	21/18639	0.0476190476190476	0.467635104621406	0.895292118907775	0.968985165472864
GO:0008373	sialyltransferase activity	1/1898	21/18639	0.0476190476190476	0.467635104621406	0.895292118907775	0.968985165472864
GO:0009975	cyclase activity	1/1898	21/18639	0.0476190476190476	0.467635104621406	0.895292118907775	0.968985165472864
GO:0019200	carbohydrate kinase activity	1/1898	21/18639	0.0476190476190476	0.467635104621406	0.895292118907775	0.968985165472864
GO:0070182	DNA polymerase binding	1/1898	21/18639	0.0476190476190476	0.467635104621406	0.895292118907775	0.968985165472864
GO:0017022	myosin binding	5/1898	76/18639	0.0657894736842105	0.646074815595364	0.897582769037584	0.970614437909409
GO:0030280	structural constituent of skin epidermis	2/1898	37/18639	0.0540540540540541	0.530829037678353	0.902536595139289	0.975118209433707
GO:0003743	translation initiation factor activity	3/1898	51/18639	0.0588235294117647	0.57766689394409	0.90342980243803	0.975230773636161
GO:0008970	phospholipase A1 activity	1/1898	22/18639	0.0454545454545455	0.446378963502251	0.905966496301321	0.975413405425464
GO:0016881	acid-amino acid ligase activity	1/1898	22/18639	0.0454545454545455	0.446378963502251	0.905966496301321	0.975413405425464
GO:0030021	extracellular matrix structural constituent conferring compression resistance	1/1898	22/18639	0.0454545454545455	0.446378963502251	0.905966496301321	0.975413405425464
GO:0046873	metal ion transmembrane transporter activity	38/1898	450/18639	0.0844444444444444	0.82927291886196	0.908222116328698	0.976519161810057
GO:0019843	rRNA binding	4/1898	65/18639	0.0615384615384615	0.604328442895355	0.908573653787674	0.976519161810057
GO:0005501	retinoid binding	2/1898	38/18639	0.0526315789473684	0.516859852476291	0.910565799777138	0.976961222677554
GO:0019840	isoprenoid binding	2/1898	38/18639	0.0526315789473684	0.516859852476291	0.910565799777138	0.976961222677554
GO:0005212	structural constituent of eye lens	1/1898	23/18639	0.0434782608695652	0.426971182480414	0.915553196092915	0.979760822831898
GO:0016849	phosphorus-oxygen lyase activity	1/1898	23/18639	0.0434782608695652	0.426971182480414	0.915553196092915	0.979760822831898
GO:0043274	phospholipase binding	1/1898	23/18639	0.0434782608695652	0.426971182480414	0.915553196092915	0.979760822831898
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	9/1898	130/18639	0.0692307692307692	0.679869498257275	0.922660173092898	0.986269412202698
GO:0005506	iron ion binding	11/1898	154/18639	0.0714285714285714	0.701452656932109	0.923231156892008	0.986269412202698
GO:0071855	neuropeptide receptor binding	2/1898	40/18639	0.05	0.491016859852476	0.924797267032899	0.987072908091377
GO:0140223	general transcription initiation factor activity	4/1898	68/18639	0.0588235294117647	0.57766689394409	0.925580502004778	0.987072908091377
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	3/1898	56/18639	0.0535714285714286	0.526089492699082	0.933943088457373	0.994275329313793
GO:0170055	lipid transmembrane transporter activity	3/1898	56/18639	0.0535714285714286	0.526089492699082	0.933943088457373	0.994275329313793
GO:0004896	cytokine receptor activity	6/1898	96/18639	0.0625	0.613771074815595	0.934799898937635	0.994331045685814
GO:0051879	Hsp90 protein binding	2/1898	42/18639	0.0476190476190476	0.467635104621406	0.936871757780179	0.995677981613329
GO:0019865	immunoglobulin binding	1/1898	26/18639	0.0384615384615385	0.377705276809597	0.938839768203598	0.996056612446049
GO:0051139	metal cation:proton antiporter activity	1/1898	26/18639	0.0384615384615385	0.377705276809597	0.938839768203598	0.996056612446049
GO:0000287	magnesium ion binding	17/1898	230/18639	0.0739130434782609	0.725851010216704	0.940997473505661	0.997489603132931
GO:0005245	voltage-gated calcium channel activity	2/1898	43/18639	0.0465116279069767	0.456759869630211	0.942195837197442	0.997904074358217
GO:0004683	calcium/calmodulin-dependent protein kinase activity	1/1898	27/18639	0.037037037037037	0.363716192483316	0.945076383469787	0.998388384588595
GO:0005104	fibroblast growth factor receptor binding	1/1898	27/18639	0.037037037037037	0.363716192483316	0.945076383469787	0.998388384588595
GO:0023026	MHC class II protein complex binding	1/1898	27/18639	0.037037037037037	0.363716192483316	0.945076383469787	0.998388384588595
GO:0030547	signaling receptor inhibitor activity	2/1898	44/18639	0.0454545454545455	0.446378963502251	0.947090926552983	0.999662156464122
GO:0008083	growth factor activity	11/1898	162/18639	0.0679012345679012	0.666813019552746	0.948118995271792	0.999893411395849
GO:0070851	growth factor receptor binding	9/1898	139/18639	0.0647482014388489	0.635849171031984	0.952020188444445	0.999999999761522
GO:0140101	catalytic activity, acting on a tRNA	9/1898	139/18639	0.0647482014388489	0.635849171031984	0.952020188444445	0.999999999761522
GO:0004252	serine-type endopeptidase activity	12/1898	176/18639	0.0681818181818182	0.669568445253377	0.952848749976916	0.999999999761522
GO:0046906	tetrapyrrole binding	10/1898	152/18639	0.0657894736842105	0.646074815595364	0.95366418987522	0.999999999761522
GO:0020037	heme binding	9/1898	142/18639	0.0633802816901408	0.622415737841167	0.959333278627116	0.999999999761522
GO:0048019	receptor antagonist activity	1/1898	30/18639	0.0333333333333333	0.327344573234984	0.960224720677982	0.999999999761522
GO:0070566	adenylyltransferase activity	1/1898	30/18639	0.0333333333333333	0.327344573234984	0.960224720677982	0.999999999761522
GO:0022824	transmitter-gated monoatomic ion channel activity	3/1898	63/18639	0.0476190476190476	0.467635104621406	0.961914583543761	0.999999999761522
GO:0022835	transmitter-gated channel activity	3/1898	63/18639	0.0476190476190476	0.467635104621406	0.961914583543761	0.999999999761522
GO:0008188	neuropeptide receptor activity	2/1898	48/18639	0.0416666666666667	0.40918071654373	0.962992736585372	0.999999999761522
GO:0047499	calcium-independent phospholipase A2 activity	1/1898	31/18639	0.032258064516129	0.316785070872565	0.964281546953075	0.999999999761522
GO:0047498	calcium-dependent phospholipase A2 activity	1/1898	32/18639	0.03125	0.306885537407798	0.96792479845152	0.999999999761522
GO:0019239	deaminase activity	1/1898	33/18639	0.0303030303030303	0.297585975668167	0.971196617258367	0.999999999761522
GO:0042923	neuropeptide binding	1/1898	33/18639	0.0303030303030303	0.297585975668167	0.971196617258367	0.999999999761522
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	1/1898	34/18639	0.0294117647058824	0.288833446972045	0.974134853335096	0.999999999761522
GO:0008135	translation factor activity, RNA binding	4/1898	83/18639	0.0481927710843374	0.473269262508411	0.974934178444341	0.999999999761522
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	2/1898	53/18639	0.0377358490566038	0.370578762152812	0.976494306118763	0.999999999761522
GO:0098960	postsynaptic neurotransmitter receptor activity	3/1898	69/18639	0.0434782608695652	0.426971182480414	0.976598021465654	0.999999999761522
GO:0180051	translation factor activity	4/1898	84/18639	0.0476190476190476	0.467635104621406	0.976759288954769	0.999999999761522
GO:0004623	phospholipase A2 activity	1/1898	35/18639	0.0285714285714286	0.280581062772844	0.976773501460331	0.999999999761522
GO:0005126	cytokine receptor binding	19/1898	275/18639	0.0690909090909091	0.678496024523422	0.976829455964997	0.999999999761522
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	1/1898	36/18639	0.0277777777777778	0.272787144362487	0.97914309371083	0.999999999761522
GO:0023023	MHC protein complex binding	1/1898	37/18639	0.027027027027027	0.265414518839176	0.981271052004484	0.999999999761522
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	3/1898	73/18639	0.0410958904109589	0.403575501248611	0.9831979931421	0.999999999761522
GO:0003924	GTPase activity	23/1898	331/18639	0.0694864048338369	0.68237992607897	0.984068792533631	0.999999999761522
GO:0046982	protein heterodimerization activity	26/1898	369/18639	0.0704607046070461	0.691947878382893	0.985729082403568	0.999999999761522
GO:0061791	GTPase motor activity	1/1898	40/18639	0.025	0.245508429926238	0.986439117639259	0.999999999761522
GO:1990606	membrane scission GTPase motor activity	1/1898	40/18639	0.025	0.245508429926238	0.986439117639259	0.999999999761522
GO:0022834	ligand-gated channel activity	11/1898	188/18639	0.0585106382978723	0.574594197699706	0.987275114774179	0.999999999761522
GO:0003735	structural constituent of ribosome	10/1898	175/18639	0.0571428571428571	0.561162125545687	0.987281153439306	0.999999999761522
GO:0004812	aminoacyl-tRNA ligase activity	1/1898	41/18639	0.024390243902439	0.239520419440232	0.9878229853053	0.999999999761522
GO:0008227	G protein-coupled amine receptor activity	1/1898	41/18639	0.024390243902439	0.239520419440232	0.9878229853053	0.999999999761522
GO:0016875	ligase activity, forming carbon-oxygen bonds	1/1898	41/18639	0.024390243902439	0.239520419440232	0.9878229853053	0.999999999761522
GO:0140828	metal cation:monoatomic cation antiporter activity	1/1898	41/18639	0.024390243902439	0.239520419440232	0.9878229853053	0.999999999761522
GO:0099094	ligand-gated monoatomic cation channel activity	7/1898	136/18639	0.0514705882352941	0.505458532201079	0.988241410023726	0.999999999761522
GO:0140767	enzyme-substrate adaptor activity	7/1898	139/18639	0.0503597122302158	0.494549355247098	0.990389619294428	0.999999999761522
GO:0030594	neurotransmitter receptor activity	4/1898	97/18639	0.0412371134020619	0.404962358641218	0.991546746083162	0.999999999761522
GO:0001664	G protein-coupled receptor binding	19/1898	297/18639	0.063973063973064	0.628237059743909	0.99179988132444	0.999999999761522
GO:0042605	peptide antigen binding	1/1898	45/18639	0.0222222222222222	0.218229715489989	0.992083634905306	0.999999999761522
GO:0001653	peptide receptor activity	6/1898	128/18639	0.046875	0.460328306111697	0.992294969134418	0.999999999761522
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/1898	46/18639	0.0217391304347826	0.213485591240207	0.992891705301656	0.999999999761522
GO:0015276	ligand-gated monoatomic ion channel activity	10/1898	186/18639	0.0537634408602151	0.527975118120942	0.993480620655448	0.999999999761522
GO:0019001	guanyl nucleotide binding	27/1898	400/18639	0.0675	0.662872760800843	0.993760816545206	0.999999999761522
GO:0032561	guanyl ribonucleotide binding	27/1898	400/18639	0.0675	0.662872760800843	0.993760816545206	0.999999999761522
GO:0005216	monoatomic ion channel activity	31/1898	448/18639	0.0691964285714286	0.679532261402981	0.993855330484839	0.999999999761522
GO:0005261	monoatomic cation channel activity	22/1898	341/18639	0.0645161290322581	0.633570141745131	0.994203398630954	0.999999999761522
GO:0005179	hormone activity	6/1898	132/18639	0.0454545454545455	0.446378963502251	0.994226376552471	0.999999999761522
GO:0038187	pattern recognition receptor activity	1/1898	48/18639	0.0208333333333333	0.204590358271865	0.994268917276352	0.999999999761522
GO:0004497	monooxygenase activity	4/1898	106/18639	0.0377358490566038	0.370578762152812	0.995914856688441	0.999999999761522
GO:0008528	G protein-coupled peptide receptor activity	5/1898	122/18639	0.040983606557377	0.402472835944653	0.996023116756151	0.999999999761522
GO:0022836	gated channel activity	19/1898	318/18639	0.059748427672956	0.586749706741953	0.997206281967896	0.999999999761522
GO:0005244	voltage-gated monoatomic ion channel activity	8/1898	173/18639	0.046242774566474	0.45411963916992	0.997538597011541	0.999999999761522
GO:0015079	potassium ion transmembrane transporter activity	7/1898	160/18639	0.04375	0.429639752370917	0.99780141125657	0.999999999761522
GO:0022832	voltage-gated channel activity	8/1898	175/18639	0.0457142857142857	0.44892970043655	0.99785974835413	0.999999999761522
GO:0005525	GTP binding	23/1898	378/18639	0.0608465608465608	0.597533744794019	0.99829322153221	0.999999999761522
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	4/1898	122/18639	0.0327868852459016	0.321978268755722	0.998926982068588	0.999999999761522
GO:0140375	immune receptor activity	6/1898	156/18639	0.0384615384615385	0.377705276809597	0.999053643399242	0.999999999761522
GO:0005267	potassium channel activity	4/1898	124/18639	0.032258064516129	0.316785070872565	0.999095235556662	0.999999999761522
GO:0005249	voltage-gated potassium channel activity	2/1898	98/18639	0.0204081632653061	0.200415044837745	0.999682280707954	0.999999999761522
GO:0005125	cytokine activity	10/1898	234/18639	0.0427350427350427	0.419672529788441	0.999737712130446	0.999999999761522
GO:0022843	voltage-gated monoatomic cation channel activity	4/1898	143/18639	0.027972027972028	0.274694746770616	0.999826646723814	0.999999999761522
GO:0003823	antigen binding	2/1898	174/18639	0.0114942528735632	0.112877439046546	0.999999853701146	0.999999999761522
GO:0045182	translation regulator activity	9/1898	356/18639	0.0252808988764045	0.248266951610803	0.99999999606738	0.999999999761522
GO:0030371	translation repressor activity	6/1898	329/18639	0.0182370820668693	0.179094295386921	0.999999999761522	0.999999999761522