ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003712	transcription coregulator activity	203/3378	495/18639	0.41010101010101	2.26283976532644	1.84599168597396e-33	2.40532716682407e-30
GO:0003714	transcription corepressor activity	94/3378	204/18639	0.46078431372549	2.54249817155992	3.00425025984911e-20	1.95726904429169e-17
GO:0031267	small GTPase binding	107/3378	283/18639	0.378091872791519	2.08622096416848	3.04011600293804e-15	1.32042371727609e-12
GO:0051020	GTPase binding	115/3378	315/18639	0.365079365079365	2.01442104372833	5.22854011856836e-15	1.60463174407281e-12
GO:0003713	transcription coactivator activity	99/3378	256/18639	0.38671875	2.13382201931616	6.15745105169917e-15	1.60463174407281e-12
GO:0008094	ATP-dependent activity, acting on DNA	85/3378	210/18639	0.404761904761905	2.23337985282923	2.44202751443933e-14	5.30326975219073e-12
GO:0140658	ATP-dependent chromatin remodeler activity	69/3378	158/18639	0.436708860759494	2.40965555230793	8.32734759843975e-14	1.55007627439528e-11
GO:0004386	helicase activity	68/3378	155/18639	0.438709677419355	2.42069558242136	9.605487430989e-14	1.56449376532233e-11
GO:0019787	ubiquitin-like protein transferase activity	152/3378	479/18639	0.317327766179541	1.75093908638853	2.30241350449514e-13	3.33338310706353e-11
GO:0061775	cohesin loader activity	66/3378	153/18639	0.431372549019608	2.38021105422631	5.77769889855669e-13	7.52834166481937e-11
GO:0016755	aminoacyltransferase activity	154/3378	496/18639	0.310483870967742	1.71317610152982	1.13434405932953e-12	1.30931670212098e-10
GO:0140297	DNA-binding transcription factor binding	152/3378	488/18639	0.311475409836066	1.71864717700842	1.20581737724112e-12	1.30931670212098e-10
GO:0140713	histone chaperone activity	68/3378	164/18639	0.414634146341463	2.28785253216653	2.4670877227143e-12	2.47278100207441e-10
GO:0000510	H3-H4 histone complex chaperone activity	64/3378	151/18639	0.423841059602649	2.33865408819828	3.35817436967167e-12	2.57394188451893e-10
GO:0140584	chromatin extrusion motor activity	64/3378	151/18639	0.423841059602649	2.33865408819828	3.35817436967167e-12	2.57394188451893e-10
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	64/3378	151/18639	0.423841059602649	2.33865408819828	3.35817436967167e-12	2.57394188451893e-10
GO:0140849	ATP-dependent H2AZ histone chaperone activity	64/3378	151/18639	0.423841059602649	2.33865408819828	3.35817436967167e-12	2.57394188451893e-10
GO:0015616	DNA translocase activity	64/3378	152/18639	0.421052631578947	2.32326820603908	4.78300469499219e-12	3.2801342724078e-10
GO:0140674	ATP-dependent histone chaperone activity	64/3378	152/18639	0.421052631578947	2.32326820603908	4.78300469499219e-12	3.2801342724078e-10
GO:0042393	histone binding	90/3378	247/18639	0.364372469635628	2.01052056291843	5.38256093151081e-12	3.50673844687929e-10
GO:0003689	DNA clamp loader activity	66/3378	160/18639	0.4125	2.27607682060391	6.81911913571852e-12	4.23110106373392e-10
GO:0004842	ubiquitin-protein transferase activity	140/3378	449/18639	0.311804008908686	1.72046030848105	8.67727272704752e-12	5.13931198333769e-10
GO:0016887	ATP hydrolysis activity	131/3378	417/18639	0.314148681055156	1.73339765132832	2.30206516309542e-11	1.30416995978841e-09
GO:0030695	GTPase regulator activity	148/3378	489/18639	0.302658486707566	1.66999749370703	2.6362075265676e-11	1.43124100296566e-09
GO:0060589	nucleoside-triphosphatase regulator activity	148/3378	490/18639	0.302040816326531	1.6665893355566	3.11372656224083e-11	1.62287428423992e-09
GO:0140597	protein carrier chaperone	72/3378	188/18639	0.382978723404255	2.11318544272703	5.06796446491782e-11	2.53982988376458e-09
GO:0140097	catalytic activity, acting on DNA	110/3378	336/18639	0.327380952380952	1.80641017508247	5.99406452724533e-11	2.80171405477377e-09
GO:0140104	molecular carrier activity	88/3378	249/18639	0.353413654618474	1.95005242996854	6.02056742391908e-11	2.80171405477377e-09
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	112/3378	349/18639	0.320916905444126	1.77074310259712	1.57052270603059e-10	7.05652098606157e-09
GO:0045296	cadherin binding	108/3378	334/18639	0.323353293413174	1.78418651152402	2.03056641399013e-10	8.81942679143047e-09
GO:0140030	modification-dependent protein binding	65/3378	173/18639	0.375722543352601	2.07314756825019	1.09301602224648e-09	4.51289620060638e-08
GO:0061659	ubiquitin-like protein ligase activity	115/3378	372/18639	0.309139784946237	1.70575975476995	1.10830912064009e-09	4.51289620060638e-08
GO:0140033	acetylation-dependent protein binding	18/3378	24/18639	0.75	4.1383214920071	1.87664775914191e-09	7.40991524291487e-08
GO:0004674	protein serine/threonine kinase activity	128/3378	433/18639	0.295612009237875	1.631116708166	2.97857194343165e-09	1.1414938947916e-07
GO:0106310	protein serine kinase activity	110/3378	361/18639	0.304709141274238	1.68131251752828	6.21049074119961e-09	2.31207698165231e-07
GO:0070577	lysine-acetylated histone binding	17/3378	23/18639	0.739130434782609	4.0783458182099	7.82734929655634e-09	2.8330655926147e-07
GO:0140857	histone H3T45 kinase activity	81/3378	246/18639	0.329268292682927	1.81682406966166	1.46272518680067e-08	5.15116464432775e-07
GO:0046332	SMAD binding	36/3378	79/18639	0.455696202531646	2.51442318501698	1.79006008339709e-08	6.03158725928337e-07
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	80/3378	243/18639	0.329218106995885	1.81654715698529	1.80531007760592e-08	6.03158725928337e-07
GO:0004679	AMP-activated protein kinase activity	81/3378	248/18639	0.326612903225806	1.80217226264826	2.19743094864037e-08	6.19869141737001e-07
GO:0004676	3-phosphoinositide-dependent protein kinase activity	80/3378	245/18639	0.326530612244898	1.80171820060173	2.71163016723017e-08	6.19869141737001e-07
GO:0004711	ribosomal protein S6 kinase activity	80/3378	245/18639	0.326530612244898	1.80171820060173	2.71163016723017e-08	6.19869141737001e-07
GO:0035175	histone H3S10 kinase activity	80/3378	245/18639	0.326530612244898	1.80171820060173	2.71163016723017e-08	6.19869141737001e-07
GO:0035979	histone H2AXS139 kinase activity	80/3378	245/18639	0.326530612244898	1.80171820060173	2.71163016723017e-08	6.19869141737001e-07
GO:0044022	histone H3S28 kinase activity	80/3378	245/18639	0.326530612244898	1.80171820060173	2.71163016723017e-08	6.19869141737001e-07
GO:0044023	histone H4S1 kinase activity	80/3378	245/18639	0.326530612244898	1.80171820060173	2.71163016723017e-08	6.19869141737001e-07
GO:0044024	histone H2AS1 kinase activity	80/3378	245/18639	0.326530612244898	1.80171820060173	2.71163016723017e-08	6.19869141737001e-07
GO:0044025	histone H2BS14 kinase activity	80/3378	245/18639	0.326530612244898	1.80171820060173	2.71163016723017e-08	6.19869141737001e-07
GO:0072354	histone H3T3 kinase activity	80/3378	245/18639	0.326530612244898	1.80171820060173	2.71163016723017e-08	6.19869141737001e-07
GO:0072371	histone H2AS121 kinase activity	80/3378	245/18639	0.326530612244898	1.80171820060173	2.71163016723017e-08	6.19869141737001e-07
GO:0072518	Rho-dependent protein serine/threonine kinase activity	80/3378	245/18639	0.326530612244898	1.80171820060173	2.71163016723017e-08	6.19869141737001e-07
GO:0140823	histone H2BS36 kinase activity	80/3378	245/18639	0.326530612244898	1.80171820060173	2.71163016723017e-08	6.19869141737001e-07
GO:0140855	histone H3S57 kinase activity	80/3378	245/18639	0.326530612244898	1.80171820060173	2.71163016723017e-08	6.19869141737001e-07
GO:0140995	histone H2A kinase activity	80/3378	245/18639	0.326530612244898	1.80171820060173	2.71163016723017e-08	6.19869141737001e-07
GO:0140997	histone H4 kinase activity	80/3378	245/18639	0.326530612244898	1.80171820060173	2.71163016723017e-08	6.19869141737001e-07
GO:0140998	histone H2B kinase activity	80/3378	245/18639	0.326530612244898	1.80171820060173	2.71163016723017e-08	6.19869141737001e-07
GO:1990244	histone H2AT120 kinase activity	80/3378	245/18639	0.326530612244898	1.80171820060173	2.71163016723017e-08	6.19869141737001e-07
GO:0004677	DNA-dependent protein kinase activity	80/3378	246/18639	0.32520325203252	1.79439414287571	3.31351208550942e-08	7.44397628865307e-07
GO:0035402	histone H3T11 kinase activity	80/3378	247/18639	0.323886639676113	1.78712938926083	4.04114188833428e-08	8.77601313416594e-07
GO:0035403	histone H3T6 kinase activity	80/3378	247/18639	0.323886639676113	1.78712938926083	4.04114188833428e-08	8.77601313416594e-07
GO:0061630	ubiquitin protein ligase activity	105/3378	353/18639	0.297450424929178	1.64126064838809	5.44283808390518e-08	1.16262590546368e-06
GO:0141003	histone H2AX kinase activity	105/3378	354/18639	0.296610169491525	1.63662431887287	6.37890627403323e-08	1.34059917339763e-06
GO:0035173	histone kinase activity	106/3378	360/18639	0.294444444444444	1.62467436352872	8.34445887587743e-08	1.72584601829655e-06
GO:0140996	histone H3 kinase activity	105/3378	357/18639	0.294117647058824	1.62287117333612	1.01962281255714e-07	2.07588831994056e-06
GO:0003724	RNA helicase activity	34/3378	77/18639	0.441558441558442	2.43641438490462	1.14967718628726e-07	2.30466057497277e-06
GO:1990841	promoter-specific chromatin binding	31/3378	68/18639	0.455882352941176	2.51545031867099	1.70561872969851e-07	3.36730485575326e-06
GO:0070063	RNA polymerase binding	28/3378	59/18639	0.474576271186441	2.61859891019659	2.36223699458419e-07	4.59402209543762e-06
GO:0008186	ATP-dependent activity, acting on RNA	34/3378	79/18639	0.430379746835443	2.37473300807159	2.44538648047968e-07	4.68579203538973e-06
GO:0016922	nuclear receptor binding	50/3378	137/18639	0.364963503649635	2.01378174793533	2.52198043022626e-07	4.76252246461569e-06
GO:0010485	histone H4 acetyltransferase activity	20/3378	35/18639	0.571428571428571	3.15300685105303	2.70980954321741e-07	5.0441169068747e-06
GO:0005096	GTPase activator activity	83/3378	271/18639	0.306273062730627	1.68994186389466	3.43735690044621e-07	6.30827611448087e-06
GO:0046966	nuclear thyroid hormone receptor binding	17/3378	28/18639	0.607142857142857	3.35006977924385	6.57487570874143e-07	1.18986986784585e-05
GO:0070064	proline-rich region binding	13/3378	18/18639	0.722222222222222	3.98505032563647	7.65370274160773e-07	1.36613351675546e-05
GO:0015923	mannosidase activity	12/3378	16/18639	0.75	4.1383214920071	1.08530463034034e-06	1.9110161261263e-05
GO:0016758	hexosyltransferase activity	63/3378	197/18639	0.319796954314721	1.76456347882536	1.74004324647852e-06	3.02303513354868e-05
GO:0043138	3'-5' DNA helicase activity	23/3378	48/18639	0.479166666666667	2.64392761989343	2.26329205144669e-06	3.88035466188821e-05
GO:0004402	histone acetyltransferase activity	21/3378	42/18639	0.5	2.7588809946714	2.61421598166798e-06	4.42379665469269e-05
GO:0140416	transcription regulator inhibitor activity	18/3378	33/18639	0.545454545454545	3.00968835782335	2.70460276565359e-06	4.51807359441875e-05
GO:0140034	methylation-dependent protein binding	31/3378	76/18639	0.407894736842105	2.25066607460036	3.27369944400188e-06	5.39953212092968e-05
GO:0008139	nuclear localization sequence binding	15/3378	25/18639	0.6	3.31065719360568	3.75443338578517e-06	6.1150333770976e-05
GO:0004559	alpha-mannosidase activity	11/3378	15/18639	0.733333333333333	4.04635879218472	4.52861158717714e-06	7.28491468900223e-05
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	26/3378	60/18639	0.433333333333333	2.39103019538188	5.32885064873596e-06	8.43918935755606e-05
GO:0003678	DNA helicase activity	30/3378	74/18639	0.405405405405405	2.23693053622006	5.44045975467927e-06	8.43918935755606e-05
GO:0035064	methylated histone binding	30/3378	74/18639	0.405405405405405	2.23693053622006	5.44045975467927e-06	8.43918935755606e-05
GO:0061733	protein-lysine-acetyltransferase activity	22/3378	47/18639	0.468085106382979	2.58278220777748	6.08211378385993e-06	9.21510960508079e-05
GO:1990518	single-stranded 3'-5' DNA helicase activity	22/3378	47/18639	0.468085106382979	2.58278220777748	6.08211378385993e-06	9.21510960508079e-05
GO:0010484	histone H3 acetyltransferase activity	16/3378	29/18639	0.551724137931034	3.04428247687879	8.02364639544115e-06	0.000120170244290343
GO:0009378	four-way junction helicase activity	22/3378	48/18639	0.458333333333333	2.52897424511545	9.31342448051729e-06	0.000136352720203528
GO:0036121	double-stranded DNA helicase activity	22/3378	48/18639	0.458333333333333	2.52897424511545	9.31342448051729e-06	0.000136352720203528
GO:0019902	phosphatase binding	59/3378	190/18639	0.310526315789474	1.71341030195382	1.01512664870627e-05	0.000146967780362697
GO:0004197	cysteine-type endopeptidase activity	33/3378	88/18639	0.375	2.06916074600355	1.36749466811196e-05	0.00019580720357691
GO:0005085	guanyl-nucleotide exchange factor activity	68/3378	230/18639	0.295652173913043	1.63133832728396	1.41714556429118e-05	0.000196147775353312
GO:0043995	histone H4K5 acetyltransferase activity	16/3378	30/18639	0.533333333333333	2.94280639431616	1.43008738745699e-05	0.000196147775353312
GO:0043996	histone H4K8 acetyltransferase activity	16/3378	30/18639	0.533333333333333	2.94280639431616	1.43008738745699e-05	0.000196147775353312
GO:0043997	histone H4K12 acetyltransferase activity	16/3378	30/18639	0.533333333333333	2.94280639431616	1.43008738745699e-05	0.000196147775353312
GO:0017124	SH3 domain binding	40/3378	115/18639	0.347826086956522	1.91922156151054	1.46706407553577e-05	0.000199123384419073
GO:0034212	protein N-acetyltransferase activity	23/3378	53/18639	0.433962264150943	2.39450048594122	1.78616534317974e-05	0.000239935406408577
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	13/3378	22/18639	0.590909090909091	3.26049572097529	2.14346859213203e-05	0.000284993834239596
GO:0061749	forked DNA-dependent helicase activity	21/3378	47/18639	0.446808510638298	2.46538301651487	2.39780114520916e-05	0.000315589383051266
GO:0036408	histone H3K14 acetyltransferase activity	15/3378	28/18639	0.535714285714286	2.95594392286222	2.47930420234438e-05	0.000323053337565472
GO:0016791	phosphatase activity	77/3378	273/18639	0.282051282051282	1.55629184314797	2.5365456482929e-05	0.000327239502943133
GO:0017116	single-stranded DNA helicase activity	24/3378	58/18639	0.413793103448276	2.28321185765909	3.09221241273579e-05	0.000395014977823013
GO:0015924	mannosyl-oligosaccharide mannosidase activity	8/3378	10/18639	0.8	4.41420959147425	3.66523840685145e-05	0.000463670450886159
GO:0016757	glycosyltransferase activity	75/3378	267/18639	0.280898876404494	1.54993314307382	3.72867533917859e-05	0.000467159996822087
GO:0044013	histone H2B acetyltransferase activity	13/3378	23/18639	0.565217391304348	3.11873503745463	4.11102818084379e-05	0.000510159020918044
GO:0042809	nuclear vitamin D receptor binding	10/3378	15/18639	0.666666666666667	3.6785079928952	4.64175448654085e-05	0.000570585480751201
GO:0008013	beta-catenin binding	36/3378	106/18639	0.339622641509434	1.87395690204095	6.81904029400971e-05	0.000830393411504174
GO:0032452	histone demethylase activity	15/3378	30/18639	0.5	2.7588809946714	7.12196293751798e-05	0.00085925163959129
GO:0043998	histone H2A acetyltransferase activity	13/3378	24/18639	0.541666666666667	2.98878774422735	7.48137812229782e-05	0.000894333549848996
GO:0042578	phosphoric ester hydrolase activity	95/3378	363/18639	0.261707988980716	1.44404239390514	7.82418118282899e-05	0.000926809825566016
GO:0140463	chromatin-protein adaptor activity	22/3378	54/18639	0.407407407407407	2.24797710676929	8.66502283769554e-05	0.00101363671450924
GO:0140938	histone H3 methyltransferase activity	20/3378	47/18639	0.425531914893617	2.34798382525226	8.71276377782305e-05	0.00101363671450924
GO:0019903	protein phosphatase binding	45/3378	144/18639	0.3125	1.72430062166963	9.18242787319911e-05	0.00105882332024588
GO:0140457	protein demethylase activity	15/3378	31/18639	0.483870967741935	2.66988483355297	0.000114937555497736	0.00130558980538061
GO:0140693	molecular condensate scaffold activity	20/3378	48/18639	0.416666666666667	2.2990674955595	0.000124087520963487	0.00130558980538061
GO:0051219	phosphoprotein binding	32/3378	93/18639	0.344086021505376	1.89858477052656	0.000127743278574777	0.00130558980538061
GO:0017056	structural constituent of nuclear pore	13/3378	25/18639	0.52	2.86923623445826	0.000130035738362032	0.00130558980538061
GO:0032931	histone H3K56 acetyltransferase activity	12/3378	22/18639	0.545454545454545	3.00968835782335	0.000130258384266676	0.00130558980538061
GO:0043992	histone H3K9 acetyltransferase activity	12/3378	22/18639	0.545454545454545	3.00968835782335	0.000130258384266676	0.00130558980538061
GO:0043993	histone H3K18 acetyltransferase activity	12/3378	22/18639	0.545454545454545	3.00968835782335	0.000130258384266676	0.00130558980538061
GO:0043994	histone H3K23 acetyltransferase activity	12/3378	22/18639	0.545454545454545	3.00968835782335	0.000130258384266676	0.00130558980538061
GO:0043999	histone H2AK5 acetyltransferase activity	12/3378	22/18639	0.545454545454545	3.00968835782335	0.000130258384266676	0.00130558980538061
GO:0044012	histone H2AK9 acetyltransferase activity	12/3378	22/18639	0.545454545454545	3.00968835782335	0.000130258384266676	0.00130558980538061
GO:0044014	histone H2BK5 acetyltransferase activity	12/3378	22/18639	0.545454545454545	3.00968835782335	0.000130258384266676	0.00130558980538061
GO:0044015	histone H2BK12 acetyltransferase activity	12/3378	22/18639	0.545454545454545	3.00968835782335	0.000130258384266676	0.00130558980538061
GO:0044016	histone H3K4 acetyltransferase activity	12/3378	22/18639	0.545454545454545	3.00968835782335	0.000130258384266676	0.00130558980538061
GO:0044017	histone H3K27 acetyltransferase activity	12/3378	22/18639	0.545454545454545	3.00968835782335	0.000130258384266676	0.00130558980538061
GO:0044018	histone H3K36 acetyltransferase activity	12/3378	22/18639	0.545454545454545	3.00968835782335	0.000130258384266676	0.00130558980538061
GO:0046972	histone H4K16 acetyltransferase activity	12/3378	22/18639	0.545454545454545	3.00968835782335	0.000130258384266676	0.00130558980538061
GO:0140908	histone H3K122 acetyltransferase activity	12/3378	22/18639	0.545454545454545	3.00968835782335	0.000130258384266676	0.00130558980538061
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	17/3378	38/18639	0.447368421052632	2.46847246891652	0.000138998219662572	0.00138255481084222
GO:0043175	RNA polymerase core enzyme binding	18/3378	42/18639	0.428571428571429	2.36475513828977	0.000174529660471692	0.0017228192999592
GO:0070717	poly-purine tract binding	15/3378	32/18639	0.46875	2.58645093250444	0.000180250619125935	0.00175273549791861
GO:0140142	nucleocytoplasmic carrier activity	15/3378	32/18639	0.46875	2.58645093250444	0.000180250619125935	0.00175273549791861
GO:0001221	transcription coregulator binding	37/3378	115/18639	0.321739130434783	1.77527994439725	0.000193765081099586	0.00187019185683526
GO:0038191	neuropilin binding	10/3378	17/18639	0.588235294117647	3.24574234667224	0.000210684981766774	0.00201854802383902
GO:0022804	active transmembrane transporter activity	113/3378	457/18639	0.2472647702407	1.36434815053772	0.000217360952748111	0.0020673089155532
GO:0000993	RNA polymerase II complex binding	16/3378	36/18639	0.444444444444444	2.45233866193014	0.00023889622661894	0.00225566509626434
GO:0004532	RNA exonuclease activity	17/3378	40/18639	0.425	2.34504884547069	0.000296810583043354	0.00278233230003949
GO:0120283	protein serine/threonine kinase binding	9/3378	15/18639	0.6	3.31065719360568	0.000362563565491062	0.00337443089882038
GO:0008234	cysteine-type peptidase activity	53/3378	187/18639	0.283422459893048	1.5638576761239	0.000379242157752608	0.00348880946043127
GO:0030215	semaphorin receptor binding	12/3378	24/18639	0.5	2.7588809946714	0.00038020793812835	0.00348880946043127
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	10/3378	18/18639	0.555555555555556	3.06542332741267	0.000397072417362009	0.00361807943931956
GO:0004713	protein tyrosine kinase activity	42/3378	140/18639	0.3	1.65532859680284	0.000410356405364746	0.00371315552909906
GO:0045322	unmethylated CpG binding	7/3378	10/18639	0.7	3.86243339253996	0.000457944527579885	0.00411518427197648
GO:0003725	double-stranded RNA binding	26/3378	75/18639	0.346666666666667	1.91282415630551	0.000463192686244291	0.00413383609709803
GO:0031625	ubiquitin protein ligase binding	78/3378	302/18639	0.258278145695364	1.42511733499582	0.000501067318990067	0.00444111612713404
GO:0042162	telomeric DNA binding	16/3378	38/18639	0.421052631578947	2.32326820603908	0.000504439897786521	0.00444111612713404
GO:0004843	cysteine-type deubiquitinase activity	34/3378	108/18639	0.314814814814815	1.73707321886718	0.000539910991713294	0.00465986406502177
GO:0019789	SUMO transferase activity	13/3378	28/18639	0.464285714285714	2.56181806648059	0.000544563656531114	0.00465986406502177
GO:0045499	chemorepellent activity	13/3378	28/18639	0.464285714285714	2.56181806648059	0.000544563656531114	0.00465986406502177
GO:0141052	histone H3 demethylase activity	13/3378	28/18639	0.464285714285714	2.56181806648059	0.000544563656531114	0.00465986406502177
GO:0035591	signaling adaptor activity	39/3378	129/18639	0.302325581395349	1.66816060142922	0.000547167461203631	0.00465986406502177
GO:0016407	acetyltransferase activity	31/3378	96/18639	0.322916666666667	1.78177730905861	0.000574754387591666	0.00486301926644117
GO:0000175	3'-5'-RNA exonuclease activity	15/3378	35/18639	0.428571428571429	2.36475513828977	0.000599244964331356	0.00500523197771639
GO:0140566	histone reader activity	15/3378	35/18639	0.428571428571429	2.36475513828977	0.000599244964331356	0.00500523197771639
GO:1990782	protein tyrosine kinase binding	36/3378	117/18639	0.307692307692308	1.69777291979779	0.000610431265574559	0.00506619069454555
GO:0004535	poly(A)-specific ribonuclease activity	8/3378	13/18639	0.615384615384615	3.39554583959557	0.00062216782854912	0.00506677925374689
GO:0070123	transforming growth factor beta receptor activity, type III	8/3378	13/18639	0.615384615384615	3.39554583959557	0.00062216782854912	0.00506677925374689
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	8/3378	13/18639	0.615384615384615	3.39554583959557	0.00062216782854912	0.00506677925374689
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	116/3378	484/18639	0.239669421487603	1.32243882389208	0.000647912075589912	0.00524366108381153
GO:0030276	clathrin binding	18/3378	46/18639	0.391304347826087	2.15912425669936	0.000666628505628464	0.0053618329804561
GO:0005024	transforming growth factor beta receptor activity	9/3378	16/18639	0.5625	3.10374111900533	0.000695507753495782	0.00555979510923315
GO:0051213	dioxygenase activity	30/3378	93/18639	0.32258064516129	1.77992322236865	0.0007129826396963	0.00560176614646887
GO:0002039	p53 binding	24/3378	69/18639	0.347826086956522	1.91922156151054	0.000713655548974546	0.00560176614646887
GO:0008080	N-acetyltransferase activity	24/3378	69/18639	0.347826086956522	1.91922156151054	0.000713655548974546	0.00560176614646887
GO:0001618	virus receptor activity	27/3378	81/18639	0.333333333333333	1.8392539964476	0.000733180719748626	0.00572056573552371
GO:0019783	ubiquitin-like protein peptidase activity	38/3378	127/18639	0.299212598425197	1.65098390232304	0.000796222202135811	0.00613892029220687
GO:0042826	histone deacetylase binding	38/3378	127/18639	0.299212598425197	1.65098390232304	0.000796222202135811	0.00613892029220687
GO:0008375	acetylglucosaminyltransferase activity	17/3378	43/18639	0.395348837209302	2.18144078648437	0.000813270169079513	0.00623347664888591
GO:0043236	laminin binding	13/3378	29/18639	0.448275862068966	2.47347951246402	0.000824358715319544	0.00627276436916843
GO:0004721	phosphoprotein phosphatase activity	49/3378	175/18639	0.28	1.54497335701599	0.000828024153105886	0.00627276436916843
GO:0140789	histone phosphatase activity	40/3378	136/18639	0.294117647058824	1.62287117333612	0.000855763189407922	0.00642822485108558
GO:0035091	phosphatidylinositol binding	73/3378	284/18639	0.257042253521127	1.41829797613389	0.000858412221096616	0.00642822485108558
GO:0101005	deubiquitinase activity	35/3378	115/18639	0.304347826086957	1.67931886632172	0.000897648666714303	0.00665820286472085
GO:0001784	phosphotyrosine residue binding	18/3378	47/18639	0.382978723404255	2.11318544272703	0.00089934282746805	0.00665820286472085
GO:0140272	exogenous protein binding	27/3378	82/18639	0.329268292682927	1.81682406966166	0.000906989723466309	0.00667687915071526
GO:0044389	ubiquitin-like protein ligase binding	81/3378	322/18639	0.251552795031056	1.3880084507353	0.000929655981350904	0.0068052906949451
GO:0031490	chromatin DNA binding	38/3378	128/18639	0.296875	1.63808559058615	0.000937678666771227	0.00682567208269782
GO:0008143	poly(A) binding	12/3378	26/18639	0.461538461538462	2.54665937969668	0.00094893802237744	0.0068313052108166
GO:0052742	phosphatidylinositol kinase activity	12/3378	26/18639	0.461538461538462	2.54665937969668	0.00094893802237744	0.0068313052108166
GO:0005048	signal sequence binding	19/3378	51/18639	0.372549019607843	2.05563681955908	0.000970566236424926	0.00694861431902021
GO:0032182	ubiquitin-like protein binding	36/3378	120/18639	0.3	1.65532859680284	0.00102226120290199	0.00725162031750736
GO:0071889	14-3-3 protein binding	14/3378	33/18639	0.424242424242424	2.34086872275149	0.00102402006018523	0.00725162031750736
GO:0045309	protein phosphorylated amino acid binding	21/3378	59/18639	0.355932203389831	1.96394918264744	0.00107064130559866	0.00754078714159486
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	29/3378	91/18639	0.318681318681319	1.75840766693342	0.00107713124628027	0.00754570975216773
GO:0015631	tubulin binding	94/3378	385/18639	0.244155844155844	1.34719383635902	0.001085327343024	0.00756246806395865
GO:0001216	DNA-binding transcription activator activity	116/3378	491/18639	0.236252545824847	1.30358531723781	0.00112541287540668	0.00780006902476012
GO:0003779	actin binding	106/3378	443/18639	0.239277652370203	1.32027713514749	0.00114514799142704	0.00789485625835679
GO:0052745	inositol phosphate phosphatase activity	10/3378	20/18639	0.5	2.7588809946714	0.0011776484752385	0.00803390556667941
GO:0061608	nuclear import signal receptor activity	10/3378	20/18639	0.5	2.7588809946714	0.0011776484752385	0.00803390556667941
GO:0031624	ubiquitin conjugating enzyme binding	13/3378	30/18639	0.433333333333333	2.39103019538188	0.00121535278702564	0.00824484161754343
GO:0061665	SUMO ligase activity	8/3378	14/18639	0.571428571428571	3.15300685105303	0.00122122366246038	0.00824484161754343
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	9/3378	17/18639	0.529411764705882	2.92116811200501	0.00124093337169091	0.00833472259439825
GO:0001727	lipid kinase activity	16/3378	41/18639	0.390243902439024	2.15327297145085	0.00135341563802624	0.00904359269922149
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	60/3378	229/18639	0.262008733624454	1.44570183126886	0.00144825988964231	0.00962797263369351
GO:0003727	single-stranded RNA binding	28/3378	89/18639	0.314606741573034	1.73592512024268	0.00161843227676512	0.0107046561249998
GO:0035035	histone acetyltransferase binding	11/3378	24/18639	0.458333333333333	2.52897424511545	0.00165693147617409	0.0108579100857999
GO:0019838	growth factor binding	39/3378	136/18639	0.286764705882353	1.58229939400272	0.00165826869307305	0.0108579100857999
GO:0035198	miRNA binding	16/3378	42/18639	0.380952380952381	2.10200456736869	0.00182292458752945	0.0118172673509993
GO:0048487	beta-tubulin binding	16/3378	42/18639	0.380952380952381	2.10200456736869	0.00182292458752945	0.0118172673509993
GO:0140312	cargo adaptor activity	10/3378	21/18639	0.476190476190476	2.62750570921086	0.00188539688060545	0.0121617432446975
GO:0000400	four-way junction DNA binding	9/3378	18/18639	0.5	2.7588809946714	0.00208479432601982	0.0132135304925387
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	9/3378	18/18639	0.5	2.7588809946714	0.00208479432601982	0.0132135304925387
GO:0030228	lipoprotein particle receptor activity	9/3378	18/18639	0.5	2.7588809946714	0.00208479432601982	0.0132135304925387
GO:0019199	transmembrane receptor protein kinase activity	25/3378	78/18639	0.320512820512821	1.76851345812269	0.00210799453887292	0.0132135304925387
GO:0005025	transforming growth factor beta receptor activity, type I	7/3378	12/18639	0.583333333333333	3.2186944937833	0.00214986067875534	0.0132135304925387
GO:0005026	transforming growth factor beta receptor activity, type II	7/3378	12/18639	0.583333333333333	3.2186944937833	0.00214986067875534	0.0132135304925387
GO:0016361	activin receptor activity, type I	7/3378	12/18639	0.583333333333333	3.2186944937833	0.00214986067875534	0.0132135304925387
GO:0016362	activin receptor activity, type II	7/3378	12/18639	0.583333333333333	3.2186944937833	0.00214986067875534	0.0132135304925387
GO:0017002	activin receptor activity	7/3378	12/18639	0.583333333333333	3.2186944937833	0.00214986067875534	0.0132135304925387
GO:1990247	N6-methyladenosine-containing RNA reader activity	7/3378	12/18639	0.583333333333333	3.2186944937833	0.00214986067875534	0.0132135304925387
GO:0061980	regulatory RNA binding	20/3378	58/18639	0.344827586206897	1.90267654804924	0.00216422301572035	0.0132393548802048
GO:0005041	low-density lipoprotein particle receptor activity	8/3378	15/18639	0.533333333333333	2.94280639431616	0.00220254948756818	0.0134108503845857
GO:0003697	single-stranded DNA binding	35/3378	121/18639	0.289256198347107	1.59604685642147	0.00237577874336611	0.0143983241981676
GO:0000030	mannosyltransferase activity	11/3378	25/18639	0.44	2.42781527531083	0.00247862782546743	0.0149520928545559
GO:0030165	PDZ domain binding	26/3378	83/18639	0.313253012048193	1.72845556292666	0.00249303534259575	0.0149697006977063
GO:0015297	antiporter activity	38/3378	135/18639	0.281481481481481	1.55314781922242	0.00270308761004543	0.0161565282380238
GO:0044390	ubiquitin-like protein conjugating enzyme binding	14/3378	36/18639	0.388888888888889	2.14579632918887	0.00276474850872772	0.0164496224058092
GO:0008093	cytoskeletal anchor activity	10/3378	22/18639	0.454545454545455	2.50807363151946	0.00289990088577414	0.017073490650144
GO:0050321	tau-protein kinase activity	10/3378	22/18639	0.454545454545455	2.50807363151946	0.00289990088577414	0.017073490650144
GO:0015291	secondary active transmembrane transporter activity	71/3378	287/18639	0.247386759581882	1.36502125868759	0.0029089139864405	0.017073490650144
GO:0030331	nuclear estrogen receptor binding	15/3378	40/18639	0.375	2.06916074600355	0.00299995736916333	0.0174506448750885
GO:0032451	demethylase activity	15/3378	40/18639	0.375	2.06916074600355	0.00299995736916333	0.0174506448750885
GO:0008194	UDP-glycosyltransferase activity	40/3378	145/18639	0.275862068965517	1.52214123843939	0.00316079919554133	0.0182994180531461
GO:0043014	alpha-tubulin binding	16/3378	44/18639	0.363636363636364	2.00645890521557	0.00317395892556486	0.0182994180531461
GO:0005518	collagen binding	23/3378	72/18639	0.319444444444444	1.76261841326229	0.00326439464171486	0.018737912855306
GO:1990380	K48-linked deubiquitinase activity	9/3378	19/18639	0.473684210526316	2.61367673179396	0.00332892842707583	0.0190245339494728
GO:0050750	low-density lipoprotein particle receptor binding	11/3378	26/18639	0.423076923076923	2.33443776472196	0.00360040034773342	0.0204861207558805
GO:0008239	dipeptidyl-peptidase activity	6/3378	10/18639	0.6	3.31065719360568	0.00379398609637254	0.0214937560155366
GO:0016410	N-acyltransferase activity	28/3378	94/18639	0.297872340425532	1.64358867767658	0.00391847655395532	0.0218957957786612
GO:0017154	semaphorin receptor activity	7/3378	13/18639	0.538461538461538	2.97110260964613	0.00393216900399594	0.0218957957786612
GO:0051011	microtubule minus-end binding	7/3378	13/18639	0.538461538461538	2.97110260964613	0.00393216900399594	0.0218957957786612
GO:0097157	pre-mRNA intronic binding	7/3378	13/18639	0.538461538461538	2.97110260964613	0.00393216900399594	0.0218957957786612
GO:0019888	protein phosphatase regulator activity	31/3378	107/18639	0.289719626168224	1.59860394083764	0.00396808140547339	0.0220017449843908
GO:0046915	transition metal ion transmembrane transporter activity	16/3378	45/18639	0.355555555555556	1.96187092954411	0.00410953206507094	0.022689492715201
GO:0038024	cargo receptor activity	21/3378	65/18639	0.323076923076923	1.78266156578768	0.00415193602939068	0.0228111912364863
GO:0008187	poly-pyrimidine tract binding	12/3378	30/18639	0.4	2.20710479573712	0.00416658750136895	0.0228111912364863
GO:0060590	ATPase regulator activity	17/3378	49/18639	0.346938775510204	1.91432558813934	0.00420608645404277	0.0229310905841746
GO:0005158	insulin receptor binding	10/3378	23/18639	0.434782608695652	2.39902695188818	0.00430615808926466	0.0232818422834517
GO:0140103	catalytic activity, acting on a glycoprotein	10/3378	23/18639	0.434782608695652	2.39902695188818	0.00430615808926466	0.0232818422834517
GO:0005516	calmodulin binding	53/3378	207/18639	0.256038647342995	1.41276031611193	0.00442093131900572	0.0238036095399358
GO:0052866	phosphatidylinositol phosphate phosphatase activity	13/3378	34/18639	0.382352941176471	2.10973252533696	0.0046014311358083	0.0246735175718445
GO:0019209	kinase activator activity	40/3378	148/18639	0.27027027027027	1.4912870241467	0.00466118513475992	0.0248914927483286
GO:0019208	phosphatase regulator activity	33/3378	117/18639	0.282051282051282	1.55629184314797	0.00478072489491631	0.0254256511758202
GO:0008266	poly(U) RNA binding	11/3378	27/18639	0.407407407407407	2.24797710676929	0.00509353062205833	0.026979147969683
GO:0002020	protease binding	37/3378	136/18639	0.272058823529412	1.50115583533591	0.00563409104760265	0.0297215410324949
GO:0043021	ribonucleoprotein complex binding	46/3378	177/18639	0.259887005649718	1.43399464129813	0.00568587820470587	0.0297930466124327
GO:0070325	lipoprotein particle receptor binding	12/3378	31/18639	0.387096774193548	2.13590786684238	0.00569337575325843	0.0297930466124327
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	8/3378	17/18639	0.470588235294118	2.59659387733779	0.00590395375492918	0.0305271894550505
GO:0019198	transmembrane receptor protein phosphatase activity	8/3378	17/18639	0.470588235294118	2.59659387733779	0.00590395375492918	0.0305271894550505
GO:0032183	SUMO binding	8/3378	17/18639	0.470588235294118	2.59659387733779	0.00590395375492918	0.0305271894550505
GO:0008017	microtubule binding	67/3378	276/18639	0.242753623188406	1.33945671480423	0.00596155922026911	0.0307032081581449
GO:0042054	histone methyltransferase activity	21/3378	67/18639	0.313432835820896	1.72944778770446	0.00614683893248727	0.0314091416824742
GO:0050840	extracellular matrix binding	21/3378	67/18639	0.313432835820896	1.72944778770446	0.00614683893248727	0.0314091416824742
GO:0070840	dynein complex binding	10/3378	24/18639	0.416666666666667	2.2990674955595	0.00619846281290077	0.0315492072078504
GO:0000217	DNA secondary structure binding	14/3378	39/18639	0.358974358974359	1.98073507309742	0.00641375377865562	0.0325179812201878
GO:0048156	tau protein binding	15/3378	43/18639	0.348837209302326	1.92480069395679	0.00658347216688318	0.0329124638487739
GO:0005545	1-phosphatidylinositol binding	7/3378	14/18639	0.5	2.7588809946714	0.0066431143455315	0.0329124638487739
GO:0030983	mismatched DNA binding	7/3378	14/18639	0.5	2.7588809946714	0.0066431143455315	0.0329124638487739
GO:0042813	Wnt receptor activity	7/3378	14/18639	0.5	2.7588809946714	0.0066431143455315	0.0329124638487739
GO:0046030	inositol trisphosphate phosphatase activity	7/3378	14/18639	0.5	2.7588809946714	0.0066431143455315	0.0329124638487739
GO:0098821	BMP receptor activity	7/3378	14/18639	0.5	2.7588809946714	0.0066431143455315	0.0329124638487739
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	26/3378	89/18639	0.292134831460674	1.61193046879677	0.00701660018644146	0.0341319175465119
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	26/3378	89/18639	0.292134831460674	1.61193046879677	0.00701660018644146	0.0341319175465119
GO:0002162	dystroglycan binding	6/3378	11/18639	0.545454545454545	3.00968835782335	0.00707261530127262	0.0341319175465119
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	6/3378	11/18639	0.545454545454545	3.00968835782335	0.00707261530127262	0.0341319175465119
GO:0032050	clathrin heavy chain binding	6/3378	11/18639	0.545454545454545	3.00968835782335	0.00707261530127262	0.0341319175465119
GO:0032404	mismatch repair complex binding	6/3378	11/18639	0.545454545454545	3.00968835782335	0.00707261530127262	0.0341319175465119
GO:0048185	activin binding	6/3378	11/18639	0.545454545454545	3.00968835782335	0.00707261530127262	0.0341319175465119
GO:0051010	microtubule plus-end binding	9/3378	21/18639	0.428571428571429	2.36475513828977	0.00749181883615028	0.0360215496070251
GO:0030971	receptor tyrosine kinase binding	24/3378	81/18639	0.296296296296296	1.63489244128676	0.00775018613567436	0.0371268107896459
GO:0001098	basal transcription machinery binding	19/3378	60/18639	0.316666666666667	1.74729129662522	0.00789675211191332	0.0374162472793565
GO:0001099	basal RNA polymerase II transcription machinery binding	19/3378	60/18639	0.316666666666667	1.74729129662522	0.00789675211191332	0.0374162472793565
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	19/3378	60/18639	0.316666666666667	1.74729129662522	0.00789675211191332	0.0374162472793565
GO:0140767	enzyme-substrate adaptor activity	37/3378	139/18639	0.266187050359712	1.4687567885301	0.00819478478536872	0.0385860920622899
GO:0140793	histone H2AXY142 phosphatase activity	26/3378	90/18639	0.288888888888889	1.59402013025459	0.00820287605621974	0.0385860920622899
GO:0004177	aminopeptidase activity	14/3378	40/18639	0.35	1.93121669626998	0.00825195184530533	0.0386773138648664
GO:0043539	protein serine/threonine kinase activator activity	22/3378	73/18639	0.301369863013699	1.66288717487043	0.00849782681845567	0.0396869833134328
GO:0015662	P-type ion transporter activity	10/3378	25/18639	0.4	2.20710479573712	0.00867835280452299	0.0402416146060265
GO:0140358	P-type transmembrane transporter activity	10/3378	25/18639	0.4	2.20710479573712	0.00867835280452299	0.0402416146060265
GO:0016279	protein-lysine N-methyltransferase activity	21/3378	69/18639	0.304347826086957	1.67931886632172	0.00886664510775838	0.0409689311184722
GO:0035615	clathrin adaptor activity	8/3378	18/18639	0.444444444444444	2.45233866193014	0.00895928129805665	0.0412506838564234
GO:0008276	protein methyltransferase activity	27/3378	95/18639	0.284210526315789	1.56820603907638	0.00901961969964424	0.0413822692557622
GO:0106222	lncRNA binding	11/3378	29/18639	0.379310344827586	2.09294420285417	0.00951089053085931	0.0434831240761743
GO:0043130	ubiquitin binding	28/3378	100/18639	0.28	1.54497335701599	0.00982598457874227	0.0447666360353188
GO:0022853	active monoatomic ion transmembrane transporter activity	32/3378	118/18639	0.271186440677966	1.49634223439805	0.0100202490519549	0.0454926289710706
GO:0051018	protein kinase A binding	17/3378	53/18639	0.320754716981132	1.7698481852609	0.0101356912204942	0.0458569640982776
GO:0048531	beta-1,3-galactosyltransferase activity	7/3378	15/18639	0.466666666666667	2.57495559502664	0.0105286085962494	0.0472484348706794
GO:0061578	K63-linked deubiquitinase activity	7/3378	15/18639	0.466666666666667	2.57495559502664	0.0105286085962494	0.0472484348706794
GO:0016278	lysine N-methyltransferase activity	21/3378	70/18639	0.3	1.65532859680284	0.0105520295835516	0.0472484348706794
GO:0140517	protein-RNA adaptor activity	9/3378	22/18639	0.409090909090909	2.25726626836751	0.0106708389556414	0.0476167916410986
GO:0034237	protein kinase A regulatory subunit binding	10/3378	26/18639	0.384615384615385	2.12221614974723	0.0118520730900165	0.0523500041908186
GO:0070006	metalloaminopeptidase activity	10/3378	26/18639	0.384615384615385	2.12221614974723	0.0118520730900165	0.0523500041908186
GO:0070412	R-SMAD binding	10/3378	26/18639	0.384615384615385	2.12221614974723	0.0118520730900165	0.0523500041908186
GO:0008408	3'-5' exonuclease activity	18/3378	58/18639	0.310344827586207	1.71240889324432	0.0119422412552398	0.0524495537271754
GO:0005095	GTPase inhibitor activity	6/3378	12/18639	0.5	2.7588809946714	0.0119953699237899	0.0524495537271754
GO:0035497	cAMP response element binding	6/3378	12/18639	0.5	2.7588809946714	0.0119953699237899	0.0524495537271754
GO:0004527	exonuclease activity	24/3378	84/18639	0.285714285714286	1.57650342552652	0.0124333247266125	0.0540020737292535
GO:0051117	ATPase binding	24/3378	84/18639	0.285714285714286	1.57650342552652	0.0124333247266125	0.0540020737292535
GO:0090482	vitamin transmembrane transporter activity	12/3378	34/18639	0.352941176470588	1.94744540800334	0.0130239392313982	0.0559522060921502
GO:0005520	insulin-like growth factor binding	8/3378	19/18639	0.421052631578947	2.32326820603908	0.0130540833860427	0.0559522060921502
GO:0042800	histone H3K4 methyltransferase activity	8/3378	19/18639	0.421052631578947	2.32326820603908	0.0130540833860427	0.0559522060921502
GO:0046527	glucosyltransferase activity	8/3378	19/18639	0.421052631578947	2.32326820603908	0.0130540833860427	0.0559522060921502
GO:0004725	protein tyrosine phosphatase activity	27/3378	98/18639	0.275510204081633	1.52019973175771	0.0137953201228865	0.0589354167872822
GO:0030295	protein kinase activator activity	36/3378	139/18639	0.258992805755396	1.42906065911037	0.0139712205591969	0.0594918313354038
GO:0036002	pre-mRNA binding	18/3378	59/18639	0.305084745762712	1.68338501369781	0.0143430883807217	0.0608763653422815
GO:0019207	kinase regulator activity	67/3378	287/18639	0.233449477351916	1.28811865256435	0.0145787664031237	0.0616757552703576
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	63/3378	268/18639	0.235074626865672	1.29708584077835	0.015073117648995	0.0635607517690632
GO:0001217	DNA-binding transcription repressor activity	65/3378	278/18639	0.233812949640288	1.2901242061413	0.0154100778784302	0.0647720370180471
GO:0030145	manganese ion binding	20/3378	68/18639	0.294117647058824	1.62287117333612	0.0154854135951193	0.0648794016541493
GO:0004707	MAP kinase activity	7/3378	16/18639	0.4375	2.41402087033748	0.0158322887765007	0.0659088571111194
GO:0034450	ubiquitin-ubiquitin ligase activity	7/3378	16/18639	0.4375	2.41402087033748	0.0158322887765007	0.0659088571111194
GO:0043495	protein-membrane adaptor activity	15/3378	47/18639	0.319148936170213	1.76098786893919	0.0159515668006877	0.0661939221060383
GO:0005543	phospholipid binding	109/3378	497/18639	0.219315895372233	1.21013291114359	0.0163840817734346	0.0677728842882074
GO:0015095	magnesium ion transmembrane transporter activity	8/3378	20/18639	0.4	2.20710479573712	0.018364094597079	0.0757228331012467
GO:0005080	protein kinase C binding	16/3378	52/18639	0.307692307692308	1.69777291979779	0.0186851558974503	0.0768036534207499
GO:0031994	insulin-like growth factor I binding	6/3378	13/18639	0.461538461538462	2.54665937969668	0.018906684997899	0.0772269923268415
GO:0046974	histone H3K9 methyltransferase activity	6/3378	13/18639	0.461538461538462	2.54665937969668	0.018906684997899	0.0772269923268415
GO:0004175	endopeptidase activity	90/3378	405/18639	0.222222222222222	1.22616933096507	0.0197327010975956	0.080349092281772
GO:0005178	integrin binding	40/3378	161/18639	0.248447204968944	1.3708725439361	0.0198204058381673	0.0804547937916885
GO:0001046	core promoter sequence-specific DNA binding	14/3378	44/18639	0.318181818181818	1.75565154206362	0.020058661426136	0.0811690553983082
GO:0015399	primary active transmembrane transporter activity	41/3378	166/18639	0.246987951807229	1.36282073230756	0.0203615237943373	0.0819438164389636
GO:1901981	phosphatidylinositol phosphate binding	45/3378	185/18639	0.243243243243243	1.34215832173203	0.0203758990991744	0.0819438164389636
GO:0097718	disordered domain specific binding	10/3378	28/18639	0.357142857142857	1.97062928190815	0.020711974497267	0.0830390854459657
GO:0016409	palmitoyltransferase activity	12/3378	36/18639	0.333333333333333	1.8392539964476	0.0209225921162086	0.0836261887344168
GO:0008378	galactosyltransferase activity	11/3378	32/18639	0.34375	1.89673068383659	0.0210025068856038	0.0836888882934
GO:0097110	scaffold protein binding	20/3378	70/18639	0.285714285714286	1.57650342552652	0.0212409206210954	0.0843808523453882
GO:0000182	rDNA binding	5/3378	10/18639	0.5	2.7588809946714	0.0219017784053211	0.0849345751849209
GO:0005522	profilin binding	5/3378	10/18639	0.5	2.7588809946714	0.0219017784053211	0.0849345751849209
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	5/3378	10/18639	0.5	2.7588809946714	0.0219017784053211	0.0849345751849209
GO:0016303	1-phosphatidylinositol-3-kinase activity	5/3378	10/18639	0.5	2.7588809946714	0.0219017784053211	0.0849345751849209
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	5/3378	10/18639	0.5	2.7588809946714	0.0219017784053211	0.0849345751849209
GO:0042975	peroxisome proliferator activated receptor binding	5/3378	10/18639	0.5	2.7588809946714	0.0219017784053211	0.0849345751849209
GO:0099122	RNA polymerase II C-terminal domain binding	5/3378	10/18639	0.5	2.7588809946714	0.0219017784053211	0.0849345751849209
GO:0140999	histone H3K4 trimethyltransferase activity	5/3378	10/18639	0.5	2.7588809946714	0.0219017784053211	0.0849345751849209
GO:0140098	catalytic activity, acting on RNA	86/3378	387/18639	0.222222222222222	1.22616933096507	0.0222288821775418	0.085947280348181
GO:0008484	sulfuric ester hydrolase activity	7/3378	17/18639	0.411764705882353	2.27201964267057	0.0227821232916008	0.0878257593164373
GO:0008238	exopeptidase activity	27/3378	102/18639	0.264705882352941	1.46058405600251	0.0231011338773373	0.0887928538117124
GO:0016798	hydrolase activity, acting on glycosyl bonds	33/3378	130/18639	0.253846153846154	1.40066265883317	0.0238932435915261	0.091567342352231
GO:0140303	intramembrane lipid transporter activity	14/3378	45/18639	0.311111111111111	1.7166370633511	0.0243909421019686	0.0932005793515106
GO:0035613	RNA stem-loop binding	8/3378	21/18639	0.380952380952381	2.10200456736869	0.0250547258345736	0.0954570402410801
GO:0140318	protein transporter activity	13/3378	41/18639	0.317073170731707	1.74953428930382	0.0252701988773107	0.0959972861140986
GO:0019706	protein-cysteine S-palmitoyltransferase activity	9/3378	25/18639	0.36	1.98639431616341	0.0262134164418562	0.0987169989125396
GO:0019707	protein-cysteine S-acyltransferase activity	9/3378	25/18639	0.36	1.98639431616341	0.0262134164418562	0.0987169989125396
GO:0042974	nuclear retinoic acid receptor binding	9/3378	25/18639	0.36	1.98639431616341	0.0262134164418562	0.0987169989125396
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	16/3378	54/18639	0.296296296296296	1.63489244128676	0.026605914241409	0.0996243915171098
GO:0016417	S-acyltransferase activity	10/3378	29/18639	0.344827586206897	1.90267654804924	0.0266072818480078	0.0996243915171098
GO:0032454	histone H3K9 demethylase activity	6/3378	14/18639	0.428571428571429	2.36475513828977	0.0281043629871747	0.104928323702833
GO:0015101	organic cation transmembrane transporter activity	22/3378	81/18639	0.271604938271605	1.49865140451286	0.028645584499456	0.106643418865118
GO:1990381	ubiquitin-specific protease binding	7/3378	18/18639	0.388888888888889	2.14579632918887	0.0315784772874925	0.117227224802287
GO:0008376	acetylgalactosaminyltransferase activity	11/3378	34/18639	0.323529411764706	1.78515829066973	0.0329127217939211	0.121833171867838
GO:0070034	telomerase RNA binding	8/3378	22/18639	0.363636363636364	2.00645890521557	0.0332740897653921	0.122821923411631
GO:0005160	transforming growth factor beta receptor binding	9/3378	26/18639	0.346153846153846	1.90999453477251	0.0338164805693009	0.12400004684985
GO:0050681	nuclear androgen receptor binding	9/3378	26/18639	0.346153846153846	1.90999453477251	0.0338164805693009	0.12400004684985
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	5/3378	11/18639	0.454545454545455	2.50807363151946	0.0342594143253616	0.12400004684985
GO:0034056	estrogen response element binding	5/3378	11/18639	0.454545454545455	2.50807363151946	0.0342594143253616	0.12400004684985
GO:0047676	arachidonate-CoA ligase activity	5/3378	11/18639	0.454545454545455	2.50807363151946	0.0342594143253616	0.12400004684985
GO:0097493	structural molecule activity conferring elasticity	5/3378	11/18639	0.454545454545455	2.50807363151946	0.0342594143253616	0.12400004684985
GO:0140031	phosphorylation-dependent protein binding	5/3378	11/18639	0.454545454545455	2.50807363151946	0.0342594143253616	0.12400004684985
GO:0019887	protein kinase regulator activity	58/3378	255/18639	0.227450980392157	1.2550203740466	0.0350432216630183	0.126485644949897
GO:0051087	protein-folding chaperone binding	33/3378	134/18639	0.246268656716418	1.35885183319636	0.0358650613766919	0.129094406005054
GO:0000149	SNARE binding	27/3378	106/18639	0.254716981132075	1.40546767653071	0.036684008037642	0.13167840901666
GO:0003684	damaged DNA binding	20/3378	74/18639	0.27027027027027	1.4912870241467	0.0375210543512686	0.13394502416357
GO:0031491	nucleosome binding	20/3378	74/18639	0.27027027027027	1.4912870241467	0.0375210543512686	0.13394502416357
GO:0030159	signaling receptor complex adaptor activity	15/3378	52/18639	0.288461538461538	1.59166211231042	0.039118507708569	0.13926616268925
GO:0000774	adenyl-nucleotide exchange factor activity	6/3378	15/18639	0.4	2.20710479573712	0.0398215325811249	0.141382716493749
GO:0019905	syntaxin binding	17/3378	61/18639	0.278688524590164	1.53773694784963	0.0400856588791263	0.14193373238995
GO:0032266	phosphatidylinositol-3-phosphate binding	14/3378	48/18639	0.291666666666667	1.60934724689165	0.0415290581092503	0.146645969421011
GO:0008381	mechanosensitive monoatomic ion channel activity	7/3378	19/18639	0.368421052631579	2.03285968028419	0.0423843737300048	0.148215748271127
GO:0140036	ubiquitin-modified protein reader activity	7/3378	19/18639	0.368421052631579	2.03285968028419	0.0423843737300048	0.148215748271127
GO:0008170	N-methyltransferase activity	25/3378	98/18639	0.255102040816327	1.4075923442201	0.042428606373853	0.148215748271127
GO:0042626	ATPase-coupled transmembrane transporter activity	25/3378	98/18639	0.255102040816327	1.4075923442201	0.042428606373853	0.148215748271127
GO:0005385	zinc ion transmembrane transporter activity	9/3378	27/18639	0.333333333333333	1.8392539964476	0.04281087770072	0.14915126642791
GO:0044325	transmembrane transporter binding	33/3378	136/18639	0.242647058823529	1.3388687180023	0.0433395466717094	0.150590478168633
GO:0001223	transcription coactivator binding	13/3378	44/18639	0.295454545454545	1.63024786048765	0.0439988573153209	0.152474763515593
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	30/3378	122/18639	0.245901639344262	1.35682671869085	0.0445498696283637	0.153974748344185
GO:1901505	carbohydrate derivative transmembrane transporter activity	15/3378	53/18639	0.283018867924528	1.56163075170079	0.0457249363947008	0.1576179685775
GO:0015179	L-amino acid transmembrane transporter activity	17/3378	62/18639	0.274193548387097	1.51293473901335	0.0462192590699769	0.158901568781477
GO:0098631	cell adhesion mediator activity	20/3378	76/18639	0.263157894736842	1.45204262877442	0.0484581125078241	0.165892083878848
GO:0001222	transcription corepressor binding	14/3378	49/18639	0.285714285714286	1.57650342552652	0.0487749607625073	0.165892083878848
GO:0000340	RNA 7-methylguanosine cap binding	5/3378	12/18639	0.416666666666667	2.2990674955595	0.0501623031836271	0.165892083878848
GO:0000995	RNA polymerase III general transcription initiation factor activity	5/3378	12/18639	0.416666666666667	2.2990674955595	0.0501623031836271	0.165892083878848
GO:0005049	nuclear export signal receptor activity	5/3378	12/18639	0.416666666666667	2.2990674955595	0.0501623031836271	0.165892083878848
GO:0005078	MAP-kinase scaffold activity	5/3378	12/18639	0.416666666666667	2.2990674955595	0.0501623031836271	0.165892083878848
GO:0005247	voltage-gated chloride channel activity	5/3378	12/18639	0.416666666666667	2.2990674955595	0.0501623031836271	0.165892083878848
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	5/3378	12/18639	0.416666666666667	2.2990674955595	0.0501623031836271	0.165892083878848
GO:0017166	vinculin binding	5/3378	12/18639	0.416666666666667	2.2990674955595	0.0501623031836271	0.165892083878848
GO:0034452	dynactin binding	5/3378	12/18639	0.416666666666667	2.2990674955595	0.0501623031836271	0.165892083878848
GO:0035197	siRNA binding	5/3378	12/18639	0.416666666666667	2.2990674955595	0.0501623031836271	0.165892083878848
GO:0035259	nuclear glucocorticoid receptor binding	5/3378	12/18639	0.416666666666667	2.2990674955595	0.0501623031836271	0.165892083878848
GO:0045295	gamma-catenin binding	5/3378	12/18639	0.416666666666667	2.2990674955595	0.0501623031836271	0.165892083878848
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	5/3378	12/18639	0.416666666666667	2.2990674955595	0.0501623031836271	0.165892083878848
GO:0070008	serine-type exopeptidase activity	5/3378	12/18639	0.416666666666667	2.2990674955595	0.0501623031836271	0.165892083878848
GO:0004715	non-membrane spanning protein tyrosine kinase activity	13/3378	45/18639	0.288888888888889	1.59402013025459	0.0519645728707452	0.171417312533116
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	15/3378	54/18639	0.277777777777778	1.53271166370634	0.0530784064536592	0.174209480123723
GO:0017069	snRNA binding	15/3378	54/18639	0.277777777777778	1.53271166370634	0.0530784064536592	0.174209480123723
GO:0005159	insulin-like growth factor receptor binding	6/3378	16/18639	0.375	2.06916074600355	0.0542150788638993	0.176165206383194
GO:0022858	alanine transmembrane transporter activity	6/3378	16/18639	0.375	2.06916074600355	0.0542150788638993	0.176165206383194
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	6/3378	16/18639	0.375	2.06916074600355	0.0542150788638993	0.176165206383194
GO:0140327	flippase activity	6/3378	16/18639	0.375	2.06916074600355	0.0542150788638993	0.176165206383194
GO:0015295	solute:proton symporter activity	8/3378	24/18639	0.333333333333333	1.8392539964476	0.0547700740841151	0.176647045870302
GO:0050431	transforming growth factor beta binding	8/3378	24/18639	0.333333333333333	1.8392539964476	0.0547700740841151	0.176647045870302
GO:0050699	WW domain binding	8/3378	24/18639	0.333333333333333	1.8392539964476	0.0547700740841151	0.176647045870302
GO:0042169	SH2 domain binding	12/3378	41/18639	0.292682926829268	1.61495472858814	0.0552696141072515	0.177100335018705
GO:0000339	RNA cap binding	7/3378	20/18639	0.35	1.93121669626998	0.0553183701861956	0.177100335018705
GO:0031418	L-ascorbic acid binding	7/3378	20/18639	0.35	1.93121669626998	0.0553183701861956	0.177100335018705
GO:0032934	sterol binding	18/3378	68/18639	0.264705882352941	1.46058405600251	0.0561175744099718	0.179218626118121
GO:0008374	O-acyltransferase activity	15/3378	55/18639	0.272727272727273	1.50484417891167	0.0612092433474217	0.194525961174855
GO:0098632	cell-cell adhesion mediator activity	15/3378	55/18639	0.272727272727273	1.50484417891167	0.0612092433474217	0.194525961174855
GO:0140311	protein sequestering activity	10/3378	33/18639	0.303030303030303	1.67204908767964	0.0620251113737463	0.196639221703142
GO:0004714	transmembrane receptor protein tyrosine kinase activity	16/3378	60/18639	0.266666666666667	1.47140319715808	0.0650890774899894	0.205852106721981
GO:0035250	UDP-galactosyltransferase activity	9/3378	29/18639	0.310344827586207	1.71240889324432	0.0652809530347069	0.205959035845576
GO:0015078	proton transmembrane transporter activity	42/3378	185/18639	0.227027027027027	1.25268110028323	0.0660514167594334	0.207886463858796
GO:0015293	symporter activity	34/3378	146/18639	0.232876712328767	1.28495827149079	0.0676851958789612	0.212515205374184
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	8/3378	25/18639	0.32	1.7656838365897	0.068208501209884	0.213643454510766
GO:0043531	ADP binding	11/3378	38/18639	0.289473684210526	1.59724689165186	0.0695428352014997	0.215713242537455
GO:0005338	nucleotide-sugar transmembrane transporter activity	5/3378	13/18639	0.384615384615385	2.12221614974723	0.0696970645497071	0.215713242537455
GO:0043560	insulin receptor substrate binding	5/3378	13/18639	0.384615384615385	2.12221614974723	0.0696970645497071	0.215713242537455
GO:0046975	histone H3K36 methyltransferase activity	5/3378	13/18639	0.384615384615385	2.12221614974723	0.0696970645497071	0.215713242537455
GO:0140852	histone ubiquitin ligase activity	5/3378	13/18639	0.384615384615385	2.12221614974723	0.0696970645497071	0.215713242537455
GO:0051787	misfolded protein binding	6/3378	17/18639	0.352941176470588	1.94744540800334	0.0713603273578805	0.219298364498392
GO:0070403	NAD+ binding	6/3378	17/18639	0.352941176470588	1.94744540800334	0.0713603273578805	0.219298364498392
GO:1990226	histone methyltransferase binding	6/3378	17/18639	0.352941176470588	1.94744540800334	0.0713603273578805	0.219298364498392
GO:0030332	cyclin binding	10/3378	34/18639	0.294117647058824	1.62287117333612	0.0741552736986735	0.227351345010286
GO:0004712	protein serine/threonine/tyrosine kinase activity	12/3378	43/18639	0.27906976744186	1.53984055516543	0.0760028503479174	0.232468812214405
GO:0008235	metalloexopeptidase activity	17/3378	66/18639	0.257575757575758	1.42124172452769	0.0773645782254943	0.236079731681075
GO:0051721	protein phosphatase 2A binding	9/3378	30/18639	0.3	1.65532859680284	0.078854886155682	0.240065225843116
GO:0015932	nucleobase-containing compound transmembrane transporter activity	15/3378	57/18639	0.263157894736842	1.45204262877442	0.0798983069214668	0.242674810999234
GO:0140296	general transcription initiation factor binding	14/3378	53/18639	0.264150943396226	1.45752203492074	0.0863526398774003	0.261668580837797
GO:0051015	actin filament binding	46/3378	209/18639	0.220095693779904	1.21443565315679	0.0866329472048001	0.261908886793166
GO:0043015	gamma-tubulin binding	10/3378	35/18639	0.285714285714286	1.57650342552652	0.0876658947870414	0.262993446973048
GO:0035401	histone H3Y41 kinase activity	27/3378	115/18639	0.234782608695652	1.29547455401962	0.0876981453359222	0.262993446973048
GO:0140801	histone H2AXY142 kinase activity	27/3378	115/18639	0.234782608695652	1.29547455401962	0.0876981453359222	0.262993446973048
GO:0140035	ubiquitin-like protein reader activity	7/3378	22/18639	0.318181818181818	1.75565154206362	0.0877990402404267	0.262993446973048
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	4/3378	10/18639	0.4	2.20710479573712	0.0901324836674531	0.265107508394337
GO:0004445	inositol-polyphosphate 5-phosphatase activity	4/3378	10/18639	0.4	2.20710479573712	0.0901324836674531	0.265107508394337
GO:0008190	eukaryotic initiation factor 4E binding	4/3378	10/18639	0.4	2.20710479573712	0.0901324836674531	0.265107508394337
GO:0015658	branched-chain amino acid transmembrane transporter activity	4/3378	10/18639	0.4	2.20710479573712	0.0901324836674531	0.265107508394337
GO:0019911	structural constituent of myelin sheath	4/3378	10/18639	0.4	2.20710479573712	0.0901324836674531	0.265107508394337
GO:0051864	histone H3K36 demethylase activity	4/3378	10/18639	0.4	2.20710479573712	0.0901324836674531	0.265107508394337
GO:0051880	G-quadruplex DNA binding	4/3378	10/18639	0.4	2.20710479573712	0.0901324836674531	0.265107508394337
GO:1905394	retromer complex binding	4/3378	10/18639	0.4	2.20710479573712	0.0901324836674531	0.265107508394337
GO:0000900	mRNA regulatory element binding translation repressor activity	6/3378	18/18639	0.333333333333333	1.8392539964476	0.0912512523930746	0.265996380018291
GO:0008308	voltage-gated monoatomic anion channel activity	6/3378	18/18639	0.333333333333333	1.8392539964476	0.0912512523930746	0.265996380018291
GO:0008409	5'-3' exonuclease activity	6/3378	18/18639	0.333333333333333	1.8392539964476	0.0912512523930746	0.265996380018291
GO:0017128	phospholipid scramblase activity	6/3378	18/18639	0.333333333333333	1.8392539964476	0.0912512523930746	0.265996380018291
GO:0004705	JUN kinase activity	5/3378	14/18639	0.357142857142857	1.97062928190815	0.0928041209733361	0.268719488062793
GO:0015926	glucosidase activity	5/3378	14/18639	0.357142857142857	1.97062928190815	0.0928041209733361	0.268719488062793
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	5/3378	14/18639	0.357142857142857	1.97062928190815	0.0928041209733361	0.268719488062793
GO:0015294	solute:monoatomic cation symporter activity	27/3378	116/18639	0.232758620689655	1.28430666993324	0.0953776809551016	0.275559020586469
GO:0004540	RNA nuclease activity	28/3378	121/18639	0.231404958677686	1.27683748513718	0.0961732443341991	0.277242781786419
GO:0005548	phospholipid transporter activity	17/3378	68/18639	0.25	1.3794404973357	0.0971624185769884	0.279476007518357
GO:0015485	cholesterol binding	14/3378	54/18639	0.259259259259259	1.43053088612591	0.0979986215757097	0.280642206402527
GO:0050661	NADP binding	14/3378	54/18639	0.259259259259259	1.43053088612591	0.0979986215757097	0.280642206402527
GO:0001671	ATPase activator activity	8/3378	27/18639	0.296296296296296	1.63489244128676	0.100623513618321	0.286271699224176
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	8/3378	27/18639	0.296296296296296	1.63489244128676	0.100623513618321	0.286271699224176
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	8/3378	27/18639	0.296296296296296	1.63489244128676	0.100623513618321	0.286271699224176
GO:0051539	4 iron, 4 sulfur cluster binding	12/3378	45/18639	0.266666666666667	1.47140319715808	0.101109720413103	0.287028247708657
GO:0004190	aspartic-type endopeptidase activity	10/3378	36/18639	0.277777777777778	1.53271166370634	0.102560693675583	0.290514312737575
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	37/3378	167/18639	0.221556886227545	1.2224981653035	0.106095379072414	0.299874791608147
GO:0008137	NADH dehydrogenase (ubiquinone) activity	11/3378	41/18639	0.268292682926829	1.48037516787246	0.109555458215652	0.307652504428867
GO:0015175	neutral L-amino acid transmembrane transporter activity	11/3378	41/18639	0.268292682926829	1.48037516787246	0.109555458215652	0.307652504428867
GO:0016877	ligase activity, forming carbon-sulfur bonds	11/3378	41/18639	0.268292682926829	1.48037516787246	0.109555458215652	0.307652504428867
GO:0022884	macromolecule transmembrane transporter activity	9/3378	32/18639	0.28125	1.55187055950266	0.110746080685945	0.310327189535024
GO:0003756	protein disulfide isomerase activity	6/3378	19/18639	0.315789473684211	1.74245115452931	0.113805196391414	0.316855066021395
GO:0008574	plus-end-directed microtubule motor activity	6/3378	19/18639	0.315789473684211	1.74245115452931	0.113805196391414	0.316855066021395
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	6/3378	19/18639	0.315789473684211	1.74245115452931	0.113805196391414	0.316855066021395
GO:0120013	lipid transfer activity	16/3378	65/18639	0.246153846153846	1.35821833583823	0.117276746345525	0.325824308077227
GO:0070001	aspartic-type peptidase activity	10/3378	37/18639	0.27027027027027	1.4912870241467	0.11882489916695	0.329283886702698
GO:0004467	long-chain fatty acid-CoA ligase activity	5/3378	15/18639	0.333333333333333	1.8392539964476	0.119295415169442	0.329283886702698
GO:0046875	ephrin receptor binding	8/3378	28/18639	0.285714285714286	1.57650342552652	0.119561407378392	0.329283886702698
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	4/3378	11/18639	0.363636363636364	2.00645890521557	0.122059951862934	0.329283886702698
GO:0004143	ATP-dependent diacylglycerol kinase activity	4/3378	11/18639	0.363636363636364	2.00645890521557	0.122059951862934	0.329283886702698
GO:0005225	volume-sensitive anion channel activity	4/3378	11/18639	0.363636363636364	2.00645890521557	0.122059951862934	0.329283886702698
GO:0008432	JUN kinase binding	4/3378	11/18639	0.363636363636364	2.00645890521557	0.122059951862934	0.329283886702698
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	4/3378	11/18639	0.363636363636364	2.00645890521557	0.122059951862934	0.329283886702698
GO:0019107	myristoyltransferase activity	4/3378	11/18639	0.363636363636364	2.00645890521557	0.122059951862934	0.329283886702698
GO:0032794	GTPase activating protein binding	4/3378	11/18639	0.363636363636364	2.00645890521557	0.122059951862934	0.329283886702698
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	4/3378	11/18639	0.363636363636364	2.00645890521557	0.122059951862934	0.329283886702698
GO:0045294	alpha-catenin binding	4/3378	11/18639	0.363636363636364	2.00645890521557	0.122059951862934	0.329283886702698
GO:0050998	nitric-oxide synthase binding	4/3378	11/18639	0.363636363636364	2.00645890521557	0.122059951862934	0.329283886702698
GO:0140537	transcription regulator activator activity	4/3378	11/18639	0.363636363636364	2.00645890521557	0.122059951862934	0.329283886702698
GO:0048027	mRNA 5'-UTR binding	7/3378	24/18639	0.291666666666667	1.60934724689165	0.128978416103156	0.346513146767861
GO:0140612	DNA damage sensor activity	7/3378	24/18639	0.291666666666667	1.60934724689165	0.128978416103156	0.346513146767861
GO:0140299	molecular sensor activity	17/3378	71/18639	0.23943661971831	1.32115427913842	0.132311397171138	0.354736112168709
GO:0042887	amide transmembrane transporter activity	10/3378	38/18639	0.263157894736842	1.45204262877442	0.136425636297468	0.365015614159346
GO:0030742	GTP-dependent protein binding	6/3378	20/18639	0.3	1.65532859680284	0.138870979050794	0.368531335444367
GO:0043024	ribosomal small subunit binding	6/3378	20/18639	0.3	1.65532859680284	0.138870979050794	0.368531335444367
GO:0140664	ATP-dependent DNA damage sensor activity	6/3378	20/18639	0.3	1.65532859680284	0.138870979050794	0.368531335444367
GO:0140939	histone H4 methyltransferase activity	6/3378	20/18639	0.3	1.65532859680284	0.138870979050794	0.368531335444367
GO:0051861	glycolipid binding	8/3378	29/18639	0.275862068965517	1.52214123843939	0.140239675699796	0.371407108611451
GO:0003688	DNA replication origin binding	5/3378	16/18639	0.3125	1.72430062166963	0.148877386217415	0.388751972427439
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	5/3378	16/18639	0.3125	1.72430062166963	0.148877386217415	0.388751972427439
GO:0005324	long-chain fatty acid transmembrane transporter activity	5/3378	16/18639	0.3125	1.72430062166963	0.148877386217415	0.388751972427439
GO:0005521	lamin binding	5/3378	16/18639	0.3125	1.72430062166963	0.148877386217415	0.388751972427439
GO:0015562	efflux transmembrane transporter activity	5/3378	16/18639	0.3125	1.72430062166963	0.148877386217415	0.388751972427439
GO:0030275	LRR domain binding	5/3378	16/18639	0.3125	1.72430062166963	0.148877386217415	0.388751972427439
GO:0070411	I-SMAD binding	5/3378	16/18639	0.3125	1.72430062166963	0.148877386217415	0.388751972427439
GO:0043022	ribosome binding	25/3378	112/18639	0.223214285714286	1.23164330119259	0.1507485443677	0.392850706622227
GO:0008483	transaminase activity	7/3378	25/18639	0.28	1.54497335701599	0.152611160783873	0.39595192872115
GO:0019211	phosphatase activator activity	7/3378	25/18639	0.28	1.54497335701599	0.152611160783873	0.39595192872115
GO:0005319	lipid transporter activity	38/3378	178/18639	0.213483146067416	1.1779491887361	0.152850207326737	0.39595192872115
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	16/3378	68/18639	0.235294117647059	1.2982969386689	0.157868988362976	0.399267330278112
GO:0005165	neurotrophin receptor binding	4/3378	12/18639	0.333333333333333	1.8392539964476	0.158008776202587	0.399267330278112
GO:0016273	arginine N-methyltransferase activity	4/3378	12/18639	0.333333333333333	1.8392539964476	0.158008776202587	0.399267330278112
GO:0016274	protein-arginine N-methyltransferase activity	4/3378	12/18639	0.333333333333333	1.8392539964476	0.158008776202587	0.399267330278112
GO:0031543	peptidyl-proline dioxygenase activity	4/3378	12/18639	0.333333333333333	1.8392539964476	0.158008776202587	0.399267330278112
GO:0035014	phosphatidylinositol 3-kinase regulator activity	4/3378	12/18639	0.333333333333333	1.8392539964476	0.158008776202587	0.399267330278112
GO:0035251	UDP-glucosyltransferase activity	4/3378	12/18639	0.333333333333333	1.8392539964476	0.158008776202587	0.399267330278112
GO:0043047	single-stranded telomeric DNA binding	4/3378	12/18639	0.333333333333333	1.8392539964476	0.158008776202587	0.399267330278112
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	4/3378	12/18639	0.333333333333333	1.8392539964476	0.158008776202587	0.399267330278112
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	4/3378	12/18639	0.333333333333333	1.8392539964476	0.158008776202587	0.399267330278112
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	4/3378	12/18639	0.333333333333333	1.8392539964476	0.158008776202587	0.399267330278112
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	4/3378	12/18639	0.333333333333333	1.8392539964476	0.158008776202587	0.399267330278112
GO:0000287	magnesium ion binding	48/3378	230/18639	0.208695652173913	1.15153293690632	0.158113539849199	0.399267330278112
GO:0003954	NADH dehydrogenase activity	11/3378	44/18639	0.25	1.3794404973357	0.160381658381624	0.404211413677478
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	19/3378	83/18639	0.228915662650602	1.26310214213871	0.161218076760477	0.405535046368535
GO:0004722	protein serine/threonine phosphatase activity	23/3378	103/18639	0.223300970873786	1.23212160927072	0.162297322372517	0.407341397711379
GO:0016769	transferase activity, transferring nitrogenous groups	8/3378	30/18639	0.266666666666667	1.47140319715808	0.1625614173522	0.407341397711379
GO:0009931	calcium-dependent protein serine/threonine kinase activity	6/3378	21/18639	0.285714285714286	1.57650342552652	0.166239293726309	0.414961302155901
GO:0072542	protein phosphatase activator activity	6/3378	21/18639	0.285714285714286	1.57650342552652	0.166239293726309	0.414961302155901
GO:0003925	G protein activity	13/3378	54/18639	0.240740740740741	1.32835010854549	0.1673801916929	0.417010305498756
GO:0004879	nuclear receptor activity	14/3378	59/18639	0.23728813559322	1.30929945509829	0.169740307653715	0.420915232031788
GO:0031593	polyubiquitin modification-dependent protein binding	14/3378	59/18639	0.23728813559322	1.30929945509829	0.169740307653715	0.420915232031788
GO:0005154	epidermal growth factor receptor binding	9/3378	35/18639	0.257142857142857	1.41885308297386	0.169916663122579	0.420915232031788
GO:0004860	protein kinase inhibitor activity	19/3378	84/18639	0.226190476190476	1.24806521187516	0.174876726641373	0.432083698723672
GO:0015036	disulfide oxidoreductase activity	10/3378	40/18639	0.25	1.3794404973357	0.175420012758881	0.432083698723672
GO:0071949	FAD binding	10/3378	40/18639	0.25	1.3794404973357	0.175420012758881	0.432083698723672
GO:0030507	spectrin binding	7/3378	26/18639	0.269230769230769	1.48555130482306	0.178075435492791	0.436972302160277
GO:0043548	phosphatidylinositol 3-kinase binding	7/3378	26/18639	0.269230769230769	1.48555130482306	0.178075435492791	0.436972302160277
GO:0008514	organic anion transmembrane transporter activity	55/3378	269/18639	0.204460966542751	1.12816694949388	0.178953138207499	0.438300637376638
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	5/3378	17/18639	0.294117647058824	1.62287117333612	0.181176160742222	0.441257079340401
GO:0005092	GDP-dissociation inhibitor activity	5/3378	17/18639	0.294117647058824	1.62287117333612	0.181176160742222	0.441257079340401
GO:0046965	nuclear retinoid X receptor binding	5/3378	17/18639	0.294117647058824	1.62287117333612	0.181176160742222	0.441257079340401
GO:0140313	molecular sequestering activity	13/3378	55/18639	0.236363636363636	1.30419828839012	0.184967131318286	0.449530292355034
GO:0016411	acylglycerol O-acyltransferase activity	8/3378	31/18639	0.258064516129032	1.42393857789492	0.186404089624453	0.449530292355034
GO:0016878	acid-thiol ligase activity	8/3378	31/18639	0.258064516129032	1.42393857789492	0.186404089624453	0.449530292355034
GO:0017147	Wnt-protein binding	8/3378	31/18639	0.258064516129032	1.42393857789492	0.186404089624453	0.449530292355034
GO:0072349	modified amino acid transmembrane transporter activity	8/3378	31/18639	0.258064516129032	1.42393857789492	0.186404089624453	0.449530292355034
GO:0098531	ligand-modulated transcription factor activity	14/3378	60/18639	0.233333333333333	1.28747779751332	0.186643045406042	0.449530292355034
GO:0019210	kinase inhibitor activity	20/3378	90/18639	0.222222222222222	1.22616933096507	0.18885697117234	0.454023308925385
GO:0004407	histone deacetylase activity	6/3378	22/18639	0.272727272727273	1.50484417891167	0.195654388783514	0.468174369492522
GO:0033558	protein lysine deacetylase activity	6/3378	22/18639	0.272727272727273	1.50484417891167	0.195654388783514	0.468174369492522
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	10/3378	41/18639	0.24390243902439	1.34579560715678	0.196666643256697	0.468174369492522
GO:0008417	fucosyltransferase activity	4/3378	13/18639	0.307692307692308	1.69777291979779	0.19725842582609	0.468174369492522
GO:0035673	oligopeptide transmembrane transporter activity	4/3378	13/18639	0.307692307692308	1.69777291979779	0.19725842582609	0.468174369492522
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	4/3378	13/18639	0.307692307692308	1.69777291979779	0.19725842582609	0.468174369492522
GO:0061459	L-arginine transmembrane transporter activity	4/3378	13/18639	0.307692307692308	1.69777291979779	0.19725842582609	0.468174369492522
GO:0004518	nuclease activity	43/3378	209/18639	0.205741626794258	1.13523332795091	0.200297915286094	0.474032342939644
GO:0005010	insulin-like growth factor receptor activity	12/3378	51/18639	0.235294117647059	1.2982969386689	0.201918237757323	0.474032342939644
GO:0005021	vascular endothelial growth factor receptor activity	12/3378	51/18639	0.235294117647059	1.2982969386689	0.201918237757323	0.474032342939644
GO:0016597	amino acid binding	12/3378	51/18639	0.235294117647059	1.2982969386689	0.201918237757323	0.474032342939644
GO:0050660	flavin adenine dinucleotide binding	19/3378	86/18639	0.22093023255814	1.21904043950597	0.203905217613177	0.474032342939644
GO:0033192	calmodulin-dependent protein phosphatase activity	18/3378	81/18639	0.222222222222222	1.22616933096507	0.204456733659238	0.474032342939644
GO:0140791	histone H2AXS140 phosphatase activity	18/3378	81/18639	0.222222222222222	1.22616933096507	0.204456733659238	0.474032342939644
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	18/3378	81/18639	0.222222222222222	1.22616933096507	0.204456733659238	0.474032342939644
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	18/3378	81/18639	0.222222222222222	1.22616933096507	0.204456733659238	0.474032342939644
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	18/3378	81/18639	0.222222222222222	1.22616933096507	0.204456733659238	0.474032342939644
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	18/3378	81/18639	0.222222222222222	1.22616933096507	0.204456733659238	0.474032342939644
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	18/3378	81/18639	0.222222222222222	1.22616933096507	0.204456733659238	0.474032342939644
GO:1990439	MAP kinase serine/threonine phosphatase activity	18/3378	81/18639	0.222222222222222	1.22616933096507	0.204456733659238	0.474032342939644
GO:0004683	calcium/calmodulin-dependent protein kinase activity	7/3378	27/18639	0.259259259259259	1.43053088612591	0.205183608148856	0.474032342939644
GO:0016405	CoA-ligase activity	7/3378	27/18639	0.259259259259259	1.43053088612591	0.205183608148856	0.474032342939644
GO:0015106	bicarbonate transmembrane transporter activity	8/3378	32/18639	0.25	1.3794404973357	0.211623425937289	0.485467119711773
GO:0042910	xenobiotic transmembrane transporter activity	8/3378	32/18639	0.25	1.3794404973357	0.211623425937289	0.485467119711773
GO:0051059	NF-kappaB binding	8/3378	32/18639	0.25	1.3794404973357	0.211623425937289	0.485467119711773
GO:0120015	sterol transfer activity	8/3378	32/18639	0.25	1.3794404973357	0.211623425937289	0.485467119711773
GO:0017075	syntaxin-1 binding	5/3378	18/18639	0.277777777777778	1.53271166370634	0.215762663953432	0.493225879177758
GO:0034185	apolipoprotein binding	5/3378	18/18639	0.277777777777778	1.53271166370634	0.215762663953432	0.493225879177758
GO:0004520	DNA endonuclease activity	10/3378	42/18639	0.238095238095238	1.31375285460543	0.218959083105322	0.499656191394456
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	18/3378	82/18639	0.219512195121951	1.2112160464411	0.220290953866561	0.500489336300214
GO:0033549	MAP kinase phosphatase activity	18/3378	82/18639	0.219512195121951	1.2112160464411	0.220290953866561	0.500489336300214
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	27/3378	128/18639	0.2109375	1.163902919627	0.220476499644146	0.500489336300214
GO:0016504	peptidase activator activity	13/3378	57/18639	0.228070175438596	1.25843694493783	0.222589227135662	0.504406544274379
GO:0008509	monoatomic anion transmembrane transporter activity	31/3378	149/18639	0.208053691275168	1.14799074946058	0.224681295148133	0.508263415934058
GO:0008171	O-methyltransferase activity	6/3378	23/18639	0.260869565217391	1.43941617113291	0.226826179055013	0.511339984963117
GO:0017134	fibroblast growth factor binding	6/3378	23/18639	0.260869565217391	1.43941617113291	0.226826179055013	0.511339984963117
GO:0015103	inorganic anion transmembrane transporter activity	34/3378	165/18639	0.206060606060606	1.13699337962215	0.229650279266366	0.516812286500993
GO:0042277	peptide binding	50/3378	249/18639	0.200803212851406	1.1079843352094	0.231959604900032	0.52110925031852
GO:0051019	mitogen-activated protein kinase binding	7/3378	28/18639	0.25	1.3794404973357	0.233724341739011	0.523269445508472
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	7/3378	28/18639	0.25	1.3794404973357	0.233724341739011	0.523269445508472
GO:0004065	arylsulfatase activity	4/3378	14/18639	0.285714285714286	1.57650342552652	0.239040147767191	0.527914089051949
GO:0008195	phosphatidate phosphatase activity	4/3378	14/18639	0.285714285714286	1.57650342552652	0.239040147767191	0.527914089051949
GO:0008474	palmitoyl-(protein) hydrolase activity	4/3378	14/18639	0.285714285714286	1.57650342552652	0.239040147767191	0.527914089051949
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	4/3378	14/18639	0.285714285714286	1.57650342552652	0.239040147767191	0.527914089051949
GO:0071933	Arp2/3 complex binding	4/3378	14/18639	0.285714285714286	1.57650342552652	0.239040147767191	0.527914089051949
GO:0098599	palmitoyl hydrolase activity	4/3378	14/18639	0.285714285714286	1.57650342552652	0.239040147767191	0.527914089051949
GO:0098847	sequence-specific single stranded DNA binding	4/3378	14/18639	0.285714285714286	1.57650342552652	0.239040147767191	0.527914089051949
GO:1901474	azole transmembrane transporter activity	4/3378	14/18639	0.285714285714286	1.57650342552652	0.239040147767191	0.527914089051949
GO:0000146	microfilament motor activity	9/3378	38/18639	0.236842105263158	1.30683836589698	0.240705603656543	0.530692726843444
GO:0031406	carboxylic acid binding	38/3378	187/18639	0.203208556149733	1.12125644703223	0.242254287229601	0.533204959898936
GO:0042562	hormone binding	20/3378	94/18639	0.212765957446809	1.17399191262613	0.249129325281123	0.546567764559146
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	5/3378	19/18639	0.263157894736842	1.45204262877442	0.252176045225581	0.546567764559146
GO:0015245	fatty acid transmembrane transporter activity	5/3378	19/18639	0.263157894736842	1.45204262877442	0.252176045225581	0.546567764559146
GO:0022821	solute:potassium antiporter activity	5/3378	19/18639	0.263157894736842	1.45204262877442	0.252176045225581	0.546567764559146
GO:0042577	lipid phosphatase activity	5/3378	19/18639	0.263157894736842	1.45204262877442	0.252176045225581	0.546567764559146
GO:0046624	sphingolipid transporter activity	5/3378	19/18639	0.263157894736842	1.45204262877442	0.252176045225581	0.546567764559146
GO:0017018	myosin phosphatase activity	18/3378	84/18639	0.214285714285714	1.18237756914489	0.253496743152778	0.546567764559146
GO:0008168	methyltransferase activity	41/3378	204/18639	0.200980392156863	1.10896196844635	0.25595340526422	0.546567764559146
GO:0004622	lysophospholipase activity	6/3378	24/18639	0.25	1.3794404973357	0.259442100038965	0.546567764559146
GO:0042625	ATPase-coupled ion transmembrane transporter activity	6/3378	24/18639	0.25	1.3794404973357	0.259442100038965	0.546567764559146
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	6/3378	24/18639	0.25	1.3794404973357	0.259442100038965	0.546567764559146
GO:0046961	proton-transporting ATPase activity, rotational mechanism	6/3378	24/18639	0.25	1.3794404973357	0.259442100038965	0.546567764559146
GO:0070300	phosphatidic acid binding	6/3378	24/18639	0.25	1.3794404973357	0.259442100038965	0.546567764559146
GO:0003785	actin monomer binding	7/3378	29/18639	0.241379310344828	1.33187358363447	0.263469462751488	0.546567764559146
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	7/3378	29/18639	0.241379310344828	1.33187358363447	0.263469462751488	0.546567764559146
GO:0097472	cyclin-dependent protein kinase activity	7/3378	29/18639	0.241379310344828	1.33187358363447	0.263469462751488	0.546567764559146
GO:0043177	organic acid binding	38/3378	189/18639	0.201058201058201	1.10939129944459	0.264869712178804	0.546567764559146
GO:0015035	protein-disulfide reductase activity	8/3378	34/18639	0.235294117647059	1.2982969386689	0.265531873807846	0.546567764559146
GO:0016763	pentosyltransferase activity	11/3378	49/18639	0.224489795918367	1.23868126291369	0.265585293693147	0.546567764559146
GO:0016790	thiolester hydrolase activity	10/3378	44/18639	0.227272727272727	1.25403681575973	0.266255091312417	0.546567764559146
GO:0051082	unfolded protein binding	25/3378	121/18639	0.206611570247934	1.14003346887248	0.266260057792679	0.546567764559146
GO:0016776	phosphotransferase activity, phosphate group as acceptor	9/3378	39/18639	0.230769230769231	1.27332968984834	0.266323459623643	0.546567764559146
GO:0004382	GDP phosphatase activity	3/3378	10/18639	0.3	1.65532859680284	0.266362648115931	0.546567764559146
GO:0005337	nucleoside transmembrane transporter activity	3/3378	10/18639	0.3	1.65532859680284	0.266362648115931	0.546567764559146
GO:0005345	purine nucleobase transmembrane transporter activity	3/3378	10/18639	0.3	1.65532859680284	0.266362648115931	0.546567764559146
GO:0005381	iron ion transmembrane transporter activity	3/3378	10/18639	0.3	1.65532859680284	0.266362648115931	0.546567764559146
GO:0008140	cAMP response element binding protein binding	3/3378	10/18639	0.3	1.65532859680284	0.266362648115931	0.546567764559146
GO:0008641	ubiquitin-like modifier activating enzyme activity	3/3378	10/18639	0.3	1.65532859680284	0.266362648115931	0.546567764559146
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	3/3378	10/18639	0.3	1.65532859680284	0.266362648115931	0.546567764559146
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	3/3378	10/18639	0.3	1.65532859680284	0.266362648115931	0.546567764559146
GO:0031957	very long-chain fatty acid-CoA ligase activity	3/3378	10/18639	0.3	1.65532859680284	0.266362648115931	0.546567764559146
GO:0032356	oxidized DNA binding	3/3378	10/18639	0.3	1.65532859680284	0.266362648115931	0.546567764559146
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	3/3378	10/18639	0.3	1.65532859680284	0.266362648115931	0.546567764559146
GO:0043121	neurotrophin binding	3/3378	10/18639	0.3	1.65532859680284	0.266362648115931	0.546567764559146
GO:0070097	delta-catenin binding	3/3378	10/18639	0.3	1.65532859680284	0.266362648115931	0.546567764559146
GO:0070513	death domain binding	3/3378	10/18639	0.3	1.65532859680284	0.266362648115931	0.546567764559146
GO:0098505	G-rich strand telomeric DNA binding	3/3378	10/18639	0.3	1.65532859680284	0.266362648115931	0.546567764559146
GO:0140135	mechanosensitive monoatomic cation channel activity	3/3378	10/18639	0.3	1.65532859680284	0.266362648115931	0.546567764559146
GO:0140940	histone H2A methyltransferase activity	3/3378	10/18639	0.3	1.65532859680284	0.266362648115931	0.546567764559146
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	3/3378	10/18639	0.3	1.65532859680284	0.266362648115931	0.546567764559146
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	3/3378	10/18639	0.3	1.65532859680284	0.266362648115931	0.546567764559146
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	3/3378	10/18639	0.3	1.65532859680284	0.266362648115931	0.546567764559146
GO:1990259	histone H2AQ104 methyltransferase activity	3/3378	10/18639	0.3	1.65532859680284	0.266362648115931	0.546567764559146
GO:0008237	metallopeptidase activity	37/3378	184/18639	0.201086956521739	1.10954996524828	0.267961266830565	0.548983538805388
GO:1902936	phosphatidylinositol bisphosphate binding	23/3378	111/18639	0.207207207207207	1.14332005184581	0.272348770220438	0.557096464045889
GO:0003774	cytoskeletal motor activity	31/3378	153/18639	0.202614379084967	1.11797791940933	0.274787986876884	0.56120493244605
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	4/3378	15/18639	0.266666666666667	1.47140319715808	0.282583686893645	0.570862858949488
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	4/3378	15/18639	0.266666666666667	1.47140319715808	0.282583686893645	0.570862858949488
GO:0005402	carbohydrate:monoatomic cation symporter activity	4/3378	15/18639	0.266666666666667	1.47140319715808	0.282583686893645	0.570862858949488
GO:0051371	muscle alpha-actinin binding	4/3378	15/18639	0.266666666666667	1.47140319715808	0.282583686893645	0.570862858949488
GO:0140776	protein-containing complex destabilizing activity	4/3378	15/18639	0.266666666666667	1.47140319715808	0.282583686893645	0.570862858949488
GO:0141050	histone H3K deacetylase activity	4/3378	15/18639	0.266666666666667	1.47140319715808	0.282583686893645	0.570862858949488
GO:0141051	histone H4K deacetylase activity	4/3378	15/18639	0.266666666666667	1.47140319715808	0.282583686893645	0.570862858949488
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	13/3378	60/18639	0.216666666666667	1.19551509769094	0.284208783410529	0.573257035269225
GO:0072341	modified amino acid binding	19/3378	91/18639	0.208791208791209	1.15206019557707	0.285163207166484	0.574293135916427
GO:0005006	epidermal growth factor receptor activity	11/3378	50/18639	0.22	1.21390763765542	0.288973875745749	0.57839164377375
GO:0005017	platelet-derived growth factor receptor activity	11/3378	50/18639	0.22	1.21390763765542	0.288973875745749	0.57839164377375
GO:0005019	platelet-derived growth factor beta-receptor activity	11/3378	50/18639	0.22	1.21390763765542	0.288973875745749	0.57839164377375
GO:0015605	organophosphate ester transmembrane transporter activity	11/3378	50/18639	0.22	1.21390763765542	0.288973875745749	0.57839164377375
GO:0003707	nuclear steroid receptor activity	6/3378	25/18639	0.24	1.32426287744227	0.29317818611952	0.582334110539229
GO:0004709	MAP kinase kinase kinase activity	6/3378	25/18639	0.24	1.32426287744227	0.29317818611952	0.582334110539229
GO:0015645	fatty acid ligase activity	6/3378	25/18639	0.24	1.32426287744227	0.29317818611952	0.582334110539229
GO:0017025	TBP-class protein binding	6/3378	25/18639	0.24	1.32426287744227	0.29317818611952	0.582334110539229
GO:0120515	fatty acid-CoA ligase activity	6/3378	25/18639	0.24	1.32426287744227	0.29317818611952	0.582334110539229
GO:0061631	ubiquitin conjugating enzyme activity	8/3378	35/18639	0.228571428571429	1.26120274042121	0.293862306603481	0.582549135145119
GO:0001968	fibronectin binding	7/3378	30/18639	0.233333333333333	1.28747779751332	0.294180607003445	0.582549135145119
GO:0015026	coreceptor activity	13/3378	61/18639	0.213114754098361	1.17591648953207	0.305846953290953	0.604732291560109
GO:0008081	phosphoric diester hydrolase activity	18/3378	87/18639	0.206896551724138	1.14160592882955	0.306571006990608	0.60524548804358
GO:0005496	steroid binding	22/3378	108/18639	0.203703703703704	1.12398855338465	0.307604660413004	0.606367431948781
GO:0005253	monoatomic anion channel activity	21/3378	103/18639	0.203883495145631	1.12498059976892	0.311749339920473	0.613609350326853
GO:0005030	neurotrophin receptor activity	11/3378	51/18639	0.215686274509804	1.19010552711315	0.312914176192566	0.614359898548808
GO:0030291	protein serine/threonine kinase inhibitor activity	10/3378	46/18639	0.217391304347826	1.19951347594409	0.316380521359021	0.614359898548808
GO:0005114	type II transforming growth factor beta receptor binding	3/3378	11/18639	0.272727272727273	1.50484417891167	0.320476159210805	0.614359898548808
GO:0008172	S-methyltransferase activity	3/3378	11/18639	0.272727272727273	1.50484417891167	0.320476159210805	0.614359898548808
GO:0008271	secondary active sulfate transmembrane transporter activity	3/3378	11/18639	0.272727272727273	1.50484417891167	0.320476159210805	0.614359898548808
GO:0015173	aromatic amino acid transmembrane transporter activity	3/3378	11/18639	0.272727272727273	1.50484417891167	0.320476159210805	0.614359898548808
GO:0015205	nucleobase transmembrane transporter activity	3/3378	11/18639	0.272727272727273	1.50484417891167	0.320476159210805	0.614359898548808
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	3/3378	11/18639	0.272727272727273	1.50484417891167	0.320476159210805	0.614359898548808
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	3/3378	11/18639	0.272727272727273	1.50484417891167	0.320476159210805	0.614359898548808
GO:0034511	U3 snoRNA binding	3/3378	11/18639	0.272727272727273	1.50484417891167	0.320476159210805	0.614359898548808
GO:0034713	type I transforming growth factor beta receptor binding	3/3378	11/18639	0.272727272727273	1.50484417891167	0.320476159210805	0.614359898548808
GO:0035252	UDP-xylosyltransferase activity	3/3378	11/18639	0.272727272727273	1.50484417891167	0.320476159210805	0.614359898548808
GO:0042285	xylosyltransferase activity	3/3378	11/18639	0.272727272727273	1.50484417891167	0.320476159210805	0.614359898548808
GO:0043522	leucine zipper domain binding	3/3378	11/18639	0.272727272727273	1.50484417891167	0.320476159210805	0.614359898548808
GO:0070990	snRNP binding	3/3378	11/18639	0.272727272727273	1.50484417891167	0.320476159210805	0.614359898548808
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	3/3378	11/18639	0.272727272727273	1.50484417891167	0.320476159210805	0.614359898548808
GO:0180030	inositol phosphate kinase activity	3/3378	11/18639	0.272727272727273	1.50484417891167	0.320476159210805	0.614359898548808
GO:0016741	transferase activity, transferring one-carbon groups	42/3378	215/18639	0.195348837209302	1.0778883886158	0.320617598628695	0.614359898548808
GO:0005452	solute:inorganic anion antiporter activity	7/3378	31/18639	0.225806451612903	1.24594625565805	0.325615424572318	0.618740935283681
GO:0008327	methyl-CpG binding	7/3378	31/18639	0.225806451612903	1.24594625565805	0.325615424572318	0.618740935283681
GO:0070273	phosphatidylinositol-4-phosphate binding	7/3378	31/18639	0.225806451612903	1.24594625565805	0.325615424572318	0.618740935283681
GO:0004708	MAP kinase kinase activity	4/3378	16/18639	0.25	1.3794404973357	0.327152453785722	0.618740935283681
GO:0031435	mitogen-activated protein kinase kinase kinase binding	4/3378	16/18639	0.25	1.3794404973357	0.327152453785722	0.618740935283681
GO:0140328	floppase activity	4/3378	16/18639	0.25	1.3794404973357	0.327152453785722	0.618740935283681
GO:0008157	protein phosphatase 1 binding	6/3378	26/18639	0.230769230769231	1.27332968984834	0.327709011307539	0.618740935283681
GO:0097602	cullin family protein binding	6/3378	26/18639	0.230769230769231	1.27332968984834	0.327709011307539	0.618740935283681
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	5/3378	21/18639	0.238095238095238	1.31375285460543	0.328602246520573	0.618740935283681
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	5/3378	21/18639	0.238095238095238	1.31375285460543	0.328602246520573	0.618740935283681
GO:0005123	death receptor binding	5/3378	21/18639	0.238095238095238	1.31375285460543	0.328602246520573	0.618740935283681
GO:0015174	basic amino acid transmembrane transporter activity	5/3378	21/18639	0.238095238095238	1.31375285460543	0.328602246520573	0.618740935283681
GO:0031072	heat shock protein binding	26/3378	131/18639	0.198473282442748	1.09512833376269	0.337219493894372	0.634050505836028
GO:0004222	metalloendopeptidase activity	22/3378	110/18639	0.2	1.10355239786856	0.34081059291385	0.639879254418943
GO:0140359	ABC-type transporter activity	10/3378	47/18639	0.212765957446809	1.17399191262613	0.342192664653622	0.641549700782259
GO:0140223	general transcription initiation factor activity	14/3378	68/18639	0.205882352941176	1.13600982133528	0.344829708116499	0.645564812752585
GO:0019894	kinesin binding	9/3378	42/18639	0.214285714285714	1.18237756914489	0.347210841932218	0.649089995749899
GO:1901682	sulfur compound transmembrane transporter activity	13/3378	63/18639	0.206349206349206	1.13858580732471	0.350302817252447	0.653932049971259
GO:0019213	deacetylase activity	8/3378	37/18639	0.216216216216216	1.19302961931736	0.352337121424158	0.656788654099682
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	12/3378	58/18639	0.206896551724138	1.14160592882955	0.356023282720256	0.662711910549276
GO:0030515	snoRNA binding	7/3378	32/18639	0.21875	1.20701043516874	0.357533184190126	0.66362640883153
GO:0043425	bHLH transcription factor binding	7/3378	32/18639	0.21875	1.20701043516874	0.357533184190126	0.66362640883153
GO:0005044	scavenger receptor activity	6/3378	27/18639	0.222222222222222	1.22616933096507	0.362716269352876	0.670381984350068
GO:0008320	protein transmembrane transporter activity	6/3378	27/18639	0.222222222222222	1.22616933096507	0.362716269352876	0.670381984350068
GO:0015252	proton channel activity	6/3378	27/18639	0.222222222222222	1.22616933096507	0.362716269352876	0.670381984350068
GO:0034062	5'-3' RNA polymerase activity	5/3378	22/18639	0.227272727272727	1.25403681575973	0.367704557619709	0.676101711179475
GO:0097747	RNA polymerase activity	5/3378	22/18639	0.227272727272727	1.25403681575973	0.367704557619709	0.676101711179475
GO:0015278	intracellularly gated calcium channel activity	4/3378	17/18639	0.235294117647059	1.2982969386689	0.372068236260646	0.676101711179475
GO:0017110	nucleoside diphosphate phosphatase activity	4/3378	17/18639	0.235294117647059	1.2982969386689	0.372068236260646	0.676101711179475
GO:0048038	quinone binding	4/3378	17/18639	0.235294117647059	1.2982969386689	0.372068236260646	0.676101711179475
GO:0004536	DNA nuclease activity	13/3378	64/18639	0.203125	1.12079540408526	0.372958572583446	0.676101711179475
GO:0004300	enoyl-CoA hydratase activity	3/3378	12/18639	0.25	1.3794404973357	0.374631953546877	0.676101711179475
GO:0008504	monoamine transmembrane transporter activity	3/3378	12/18639	0.25	1.3794404973357	0.374631953546877	0.676101711179475
GO:0015368	calcium:monoatomic cation antiporter activity	3/3378	12/18639	0.25	1.3794404973357	0.374631953546877	0.676101711179475
GO:0016423	tRNA (guanine) methyltransferase activity	3/3378	12/18639	0.25	1.3794404973357	0.374631953546877	0.676101711179475
GO:0036009	protein-glutamine N-methyltransferase activity	3/3378	12/18639	0.25	1.3794404973357	0.374631953546877	0.676101711179475
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	3/3378	12/18639	0.25	1.3794404973357	0.374631953546877	0.676101711179475
GO:0070410	co-SMAD binding	3/3378	12/18639	0.25	1.3794404973357	0.374631953546877	0.676101711179475
GO:0097371	MDM2/MDM4 family protein binding	3/3378	12/18639	0.25	1.3794404973357	0.374631953546877	0.676101711179475
GO:0140829	bicarbonate:monoatomic anion antiporter activity	3/3378	12/18639	0.25	1.3794404973357	0.374631953546877	0.676101711179475
GO:0140900	chloride:bicarbonate antiporter activity	3/3378	12/18639	0.25	1.3794404973357	0.374631953546877	0.676101711179475
GO:0141221	histone deacetylase activity, hydrolytic mechanism	3/3378	12/18639	0.25	1.3794404973357	0.374631953546877	0.676101711179475
GO:0001786	phosphatidylserine binding	12/3378	59/18639	0.203389830508475	1.12225667579854	0.37975615315703	0.684401476574841
GO:0046943	carboxylic acid transmembrane transporter activity	36/3378	188/18639	0.191489361702128	1.05659272136352	0.385904723798261	0.694521899322008
GO:0051287	NAD binding	11/3378	54/18639	0.203703703703704	1.12398855338465	0.386972825593244	0.695483574824823
GO:0005004	GPI-linked ephrin receptor activity	10/3378	49/18639	0.204081632653061	1.12607387537608	0.394680822302966	0.699685865933013
GO:0005008	hepatocyte growth factor receptor activity	10/3378	49/18639	0.204081632653061	1.12607387537608	0.394680822302966	0.699685865933013
GO:0005009	insulin receptor activity	10/3378	49/18639	0.204081632653061	1.12607387537608	0.394680822302966	0.699685865933013
GO:0005011	macrophage colony-stimulating factor receptor activity	10/3378	49/18639	0.204081632653061	1.12607387537608	0.394680822302966	0.699685865933013
GO:0005018	platelet-derived growth factor alpha-receptor activity	10/3378	49/18639	0.204081632653061	1.12607387537608	0.394680822302966	0.699685865933013
GO:0005020	stem cell factor receptor activity	10/3378	49/18639	0.204081632653061	1.12607387537608	0.394680822302966	0.699685865933013
GO:0008288	boss receptor activity	10/3378	49/18639	0.204081632653061	1.12607387537608	0.394680822302966	0.699685865933013
GO:0036332	placental growth factor receptor activity	10/3378	49/18639	0.204081632653061	1.12607387537608	0.394680822302966	0.699685865933013
GO:0038062	protein tyrosine kinase collagen receptor activity	10/3378	49/18639	0.204081632653061	1.12607387537608	0.394680822302966	0.699685865933013
GO:0060175	brain-derived neurotrophic factor receptor activity	10/3378	49/18639	0.204081632653061	1.12607387537608	0.394680822302966	0.699685865933013
GO:0160215	deacylase activity	13/3378	65/18639	0.2	1.10355239786856	0.395791183070462	0.700700966767407
GO:0051393	alpha-actinin binding	6/3378	28/18639	0.214285714285714	1.18237756914489	0.39789588597484	0.70251807510192
GO:0051959	dynein light intermediate chain binding	6/3378	28/18639	0.214285714285714	1.18237756914489	0.39789588597484	0.70251807510192
GO:0005342	organic acid transmembrane transporter activity	36/3378	189/18639	0.19047619047619	1.05100228368434	0.399275842841648	0.704000572696437
GO:0019205	nucleobase-containing compound kinase activity	9/3378	44/18639	0.204545454545455	1.12863313418376	0.402975166216984	0.709563029163148
GO:0003887	DNA-directed DNA polymerase activity	5/3378	23/18639	0.217391304347826	1.19951347594409	0.406837440554347	0.711555953076932
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	5/3378	23/18639	0.217391304347826	1.19951347594409	0.406837440554347	0.711555953076932
GO:0042171	lysophosphatidic acid acyltransferase activity	5/3378	23/18639	0.217391304347826	1.19951347594409	0.406837440554347	0.711555953076932
GO:0071617	lysophospholipid acyltransferase activity	5/3378	23/18639	0.217391304347826	1.19951347594409	0.406837440554347	0.711555953076932
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	5/3378	23/18639	0.217391304347826	1.19951347594409	0.406837440554347	0.711555953076932
GO:0004620	phospholipase activity	21/3378	109/18639	0.192660550458716	1.06305506216696	0.416385756016991	0.723993657974466
GO:0004706	JUN kinase kinase kinase activity	4/3378	18/18639	0.222222222222222	1.22616933096507	0.416726971205564	0.723993657974466
GO:0015172	acidic amino acid transmembrane transporter activity	4/3378	18/18639	0.222222222222222	1.22616933096507	0.416726971205564	0.723993657974466
GO:0050811	GABA receptor binding	4/3378	18/18639	0.222222222222222	1.22616933096507	0.416726971205564	0.723993657974466
GO:0098641	cadherin binding involved in cell-cell adhesion	4/3378	18/18639	0.222222222222222	1.22616933096507	0.416726971205564	0.723993657974466
GO:0015085	calcium ion transmembrane transporter activity	28/3378	147/18639	0.19047619047619	1.05100228368434	0.418300011347304	0.725758874547986
GO:0005007	fibroblast growth factor receptor activity	10/3378	50/18639	0.2	1.10355239786856	0.421107558942271	0.729658443220451
GO:0015020	glucuronosyltransferase activity	7/3378	34/18639	0.205882352941176	1.13600982133528	0.421891322684377	0.730045675242686
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	3/3378	13/18639	0.230769230769231	1.27332968984834	0.427844011863113	0.734757535563696
GO:0005542	folic acid binding	3/3378	13/18639	0.230769230769231	1.27332968984834	0.427844011863113	0.734757535563696
GO:0140333	glycerophospholipid flippase activity	3/3378	13/18639	0.230769230769231	1.27332968984834	0.427844011863113	0.734757535563696
GO:0140410	monoatomic cation:bicarbonate symporter activity	3/3378	13/18639	0.230769230769231	1.27332968984834	0.427844011863113	0.734757535563696
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	3/3378	13/18639	0.230769230769231	1.27332968984834	0.427844011863113	0.734757535563696
GO:0016651	oxidoreductase activity, acting on NAD(P)H	17/3378	88/18639	0.193181818181818	1.06593129339577	0.427997674207863	0.734757535563696
GO:0004629	phospholipase C activity	6/3378	29/18639	0.206896551724138	1.14160592882955	0.432963648554845	0.742304781667057
GO:0005254	chloride channel activity	16/3378	83/18639	0.192771084337349	1.06366496180102	0.436326641869138	0.746630423847017
GO:0015108	chloride transmembrane transporter activity	23/3378	121/18639	0.190082644628099	1.04883079136268	0.436632680714832	0.746630423847017
GO:0016500	protein-hormone receptor activity	13/3378	67/18639	0.194029850746269	1.07061053524562	0.44166748612681	0.750545439640983
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	8/3378	40/18639	0.2	1.10355239786856	0.441802265698107	0.750545439640983
GO:0061791	GTPase motor activity	8/3378	40/18639	0.2	1.10355239786856	0.441802265698107	0.750545439640983
GO:0140662	ATP-dependent protein folding chaperone	8/3378	40/18639	0.2	1.10355239786856	0.441802265698107	0.750545439640983
GO:1990606	membrane scission GTPase motor activity	8/3378	40/18639	0.2	1.10355239786856	0.441802265698107	0.750545439640983
GO:0009055	electron transfer activity	22/3378	116/18639	0.189655172413793	1.04647210142708	0.444183260044093	0.753607796663351
GO:0016830	carbon-carbon lyase activity	10/3378	51/18639	0.196078431372549	1.08191411555741	0.447496188881223	0.757256537808096
GO:0030544	Hsp70 protein binding	10/3378	51/18639	0.196078431372549	1.08191411555741	0.447496188881223	0.757256537808096
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	9/3378	46/18639	0.195652173913043	1.07956212834968	0.458833825092035	0.772421113549584
GO:0005346	purine ribonucleotide transmembrane transporter activity	4/3378	19/18639	0.210526315789474	1.16163410301954	0.460607218133559	0.772421113549584
GO:0030506	ankyrin binding	4/3378	19/18639	0.210526315789474	1.16163410301954	0.460607218133559	0.772421113549584
GO:0031420	alkali metal ion binding	4/3378	19/18639	0.210526315789474	1.16163410301954	0.460607218133559	0.772421113549584
GO:0050145	nucleoside monophosphate kinase activity	4/3378	19/18639	0.210526315789474	1.16163410301954	0.460607218133559	0.772421113549584
GO:0097001	ceramide binding	4/3378	19/18639	0.210526315789474	1.16163410301954	0.460607218133559	0.772421113549584
GO:0120227	acyl-CoA binding	4/3378	19/18639	0.210526315789474	1.16163410301954	0.460607218133559	0.772421113549584
GO:0019842	vitamin binding	28/3378	150/18639	0.186666666666667	1.02998223801066	0.464443969994104	0.777043657719558
GO:0003777	microtubule motor activity	13/3378	68/18639	0.191176470588235	1.05486626266848	0.464556415474701	0.777043657719558
GO:0015370	solute:sodium symporter activity	15/3378	79/18639	0.189873417721519	1.04767632709041	0.466376565365402	0.778237815903361
GO:0001965	G-protein alpha-subunit binding	6/3378	30/18639	0.2	1.10355239786856	0.467659408942695	0.778237815903361
GO:0008106	alcohol dehydrogenase (NADP+) activity	6/3378	30/18639	0.2	1.10355239786856	0.467659408942695	0.778237815903361
GO:0035925	mRNA 3'-UTR AU-rich region binding	6/3378	30/18639	0.2	1.10355239786856	0.467659408942695	0.778237815903361
GO:0017080	sodium channel regulator activity	8/3378	41/18639	0.195121951219512	1.07663648572543	0.471395948974352	0.780718468952836
GO:0061650	ubiquitin-like protein conjugating enzyme activity	8/3378	41/18639	0.195121951219512	1.07663648572543	0.471395948974352	0.780718468952836
GO:0140828	metal cation:monoatomic cation antiporter activity	8/3378	41/18639	0.195121951219512	1.07663648572543	0.471395948974352	0.780718468952836
GO:0005507	copper ion binding	12/3378	63/18639	0.19047619047619	1.05100228368434	0.475333509774326	0.780718468952836
GO:0008174	mRNA methyltransferase activity	3/3378	14/18639	0.214285714285714	1.18237756914489	0.479335974798365	0.780718468952836
GO:0008494	translation activator activity	3/3378	14/18639	0.214285714285714	1.18237756914489	0.479335974798365	0.780718468952836
GO:0008559	ABC-type xenobiotic transporter activity	3/3378	14/18639	0.214285714285714	1.18237756914489	0.479335974798365	0.780718468952836
GO:0015386	potassium:proton antiporter activity	3/3378	14/18639	0.214285714285714	1.18237756914489	0.479335974798365	0.780718468952836
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	3/3378	14/18639	0.214285714285714	1.18237756914489	0.479335974798365	0.780718468952836
GO:0019992	diacylglycerol binding	3/3378	14/18639	0.214285714285714	1.18237756914489	0.479335974798365	0.780718468952836
GO:0031404	chloride ion binding	3/3378	14/18639	0.214285714285714	1.18237756914489	0.479335974798365	0.780718468952836
GO:0034236	protein kinase A catalytic subunit binding	3/3378	14/18639	0.214285714285714	1.18237756914489	0.479335974798365	0.780718468952836
GO:0042043	neurexin family protein binding	3/3378	14/18639	0.214285714285714	1.18237756914489	0.479335974798365	0.780718468952836
GO:0044548	S100 protein binding	3/3378	14/18639	0.214285714285714	1.18237756914489	0.479335974798365	0.780718468952836
GO:0070742	C2H2 zinc finger domain binding	3/3378	14/18639	0.214285714285714	1.18237756914489	0.479335974798365	0.780718468952836
GO:1901612	cardiolipin binding	3/3378	14/18639	0.214285714285714	1.18237756914489	0.479335974798365	0.780718468952836
GO:1990825	sequence-specific mRNA binding	3/3378	14/18639	0.214285714285714	1.18237756914489	0.479335974798365	0.780718468952836
GO:0047617	fatty acyl-CoA hydrolase activity	5/3378	25/18639	0.2	1.10355239786856	0.483737563543113	0.785922749746479
GO:0120020	cholesterol transfer activity	5/3378	25/18639	0.2	1.10355239786856	0.483737563543113	0.785922749746479
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	16/3378	86/18639	0.186046511627907	1.02656037011029	0.497728802895103	0.805607638862393
GO:0044183	protein folding chaperone	14/3378	75/18639	0.186666666666667	1.02998223801066	0.498306307634752	0.805607638862393
GO:0005003	ephrin receptor activity	10/3378	53/18639	0.188679245283019	1.04108716780053	0.499713061664347	0.805607638862393
GO:0005005	transmembrane-ephrin receptor activity	10/3378	53/18639	0.188679245283019	1.04108716780053	0.499713061664347	0.805607638862393
GO:0017046	peptide hormone binding	10/3378	53/18639	0.188679245283019	1.04108716780053	0.499713061664347	0.805607638862393
GO:0038064	collagen receptor activity	10/3378	53/18639	0.188679245283019	1.04108716780053	0.499713061664347	0.805607638862393
GO:0051879	Hsp90 protein binding	8/3378	42/18639	0.19047619047619	1.05100228368434	0.500615974160737	0.805607638862393
GO:0005310	dicarboxylic acid transmembrane transporter activity	6/3378	31/18639	0.193548387096774	1.06795393342119	0.501749965191586	0.805607638862393
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	4/3378	20/18639	0.2	1.10355239786856	0.503272922512654	0.805607638862393
GO:0005326	neurotransmitter transmembrane transporter activity	4/3378	20/18639	0.2	1.10355239786856	0.503272922512654	0.805607638862393
GO:0016004	phospholipase activator activity	4/3378	20/18639	0.2	1.10355239786856	0.503272922512654	0.805607638862393
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	4/3378	20/18639	0.2	1.10355239786856	0.503272922512654	0.805607638862393
GO:0043178	alcohol binding	17/3378	92/18639	0.184782608695652	1.01958645455248	0.507280089786904	0.811025714101025
GO:0042805	actinin binding	7/3378	37/18639	0.189189189189189	1.04390091690269	0.516606437632063	0.823914551082714
GO:0043394	proteoglycan binding	7/3378	37/18639	0.189189189189189	1.04390091690269	0.516606437632063	0.823914551082714
GO:0005112	Notch binding	5/3378	26/18639	0.192307692307692	1.06110807487362	0.520887218837297	0.825688620614354
GO:0005227	calcium-activated cation channel activity	5/3378	26/18639	0.192307692307692	1.06110807487362	0.520887218837297	0.825688620614354
GO:0015145	monosaccharide transmembrane transporter activity	5/3378	26/18639	0.192307692307692	1.06110807487362	0.520887218837297	0.825688620614354
GO:0016289	acyl-CoA hydrolase activity	5/3378	26/18639	0.192307692307692	1.06110807487362	0.520887218837297	0.825688620614354
GO:0051139	metal cation:proton antiporter activity	5/3378	26/18639	0.192307692307692	1.06110807487362	0.520887218837297	0.825688620614354
GO:0004129	cytochrome-c oxidase activity	3/3378	15/18639	0.2	1.10355239786856	0.528524046774545	0.830719943241534
GO:0008242	omega peptidase activity	3/3378	15/18639	0.2	1.10355239786856	0.528524046774545	0.830719943241534
GO:0015116	sulfate transmembrane transporter activity	3/3378	15/18639	0.2	1.10355239786856	0.528524046774545	0.830719943241534
GO:0015556	C4-dicarboxylate transmembrane transporter activity	3/3378	15/18639	0.2	1.10355239786856	0.528524046774545	0.830719943241534
GO:0015929	hexosaminidase activity	3/3378	15/18639	0.2	1.10355239786856	0.528524046774545	0.830719943241534
GO:0033130	acetylcholine receptor binding	3/3378	15/18639	0.2	1.10355239786856	0.528524046774545	0.830719943241534
GO:0050780	dopamine receptor binding	3/3378	15/18639	0.2	1.10355239786856	0.528524046774545	0.830719943241534
GO:0031369	translation initiation factor binding	6/3378	32/18639	0.1875	1.03458037300178	0.535030760807307	0.839933832930026
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	4/3378	21/18639	0.19047619047619	1.05100228368434	0.544371905099026	0.85356990655118
GO:0005109	frizzled binding	7/3378	38/18639	0.184210526315789	1.0164298401421	0.546977611189776	0.856624792524373
GO:0035255	ionotropic glutamate receptor binding	5/3378	27/18639	0.185185185185185	1.02180777580422	0.556835161901939	0.865039990027136
GO:0001094	TFIID-class transcription factor complex binding	2/3378	10/18639	0.2	1.10355239786856	0.564964721038444	0.865039990027136
GO:0004090	carbonyl reductase (NADPH) activity	2/3378	10/18639	0.2	1.10355239786856	0.564964721038444	0.865039990027136
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	2/3378	10/18639	0.2	1.10355239786856	0.564964721038444	0.865039990027136
GO:0005131	growth hormone receptor binding	2/3378	10/18639	0.2	1.10355239786856	0.564964721038444	0.865039990027136
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	2/3378	10/18639	0.2	1.10355239786856	0.564964721038444	0.865039990027136
GO:0015187	glycine transmembrane transporter activity	2/3378	10/18639	0.2	1.10355239786856	0.564964721038444	0.865039990027136
GO:0015203	polyamine transmembrane transporter activity	2/3378	10/18639	0.2	1.10355239786856	0.564964721038444	0.865039990027136
GO:0015279	store-operated calcium channel activity	2/3378	10/18639	0.2	1.10355239786856	0.564964721038444	0.865039990027136
GO:0016175	superoxide-generating NAD(P)H oxidase activity	2/3378	10/18639	0.2	1.10355239786856	0.564964721038444	0.865039990027136
GO:0016427	tRNA (cytidine) methyltransferase activity	2/3378	10/18639	0.2	1.10355239786856	0.564964721038444	0.865039990027136
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	2/3378	10/18639	0.2	1.10355239786856	0.564964721038444	0.865039990027136
GO:0031419	cobalamin binding	2/3378	10/18639	0.2	1.10355239786856	0.564964721038444	0.865039990027136
GO:0031434	mitogen-activated protein kinase kinase binding	2/3378	10/18639	0.2	1.10355239786856	0.564964721038444	0.865039990027136
GO:0031996	thioesterase binding	2/3378	10/18639	0.2	1.10355239786856	0.564964721038444	0.865039990027136
GO:0043295	glutathione binding	2/3378	10/18639	0.2	1.10355239786856	0.564964721038444	0.865039990027136
GO:0043422	protein kinase B binding	2/3378	10/18639	0.2	1.10355239786856	0.564964721038444	0.865039990027136
GO:0050308	sugar-phosphatase activity	2/3378	10/18639	0.2	1.10355239786856	0.564964721038444	0.865039990027136
GO:0050815	phosphoserine residue binding	2/3378	10/18639	0.2	1.10355239786856	0.564964721038444	0.865039990027136
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	6/3378	33/18639	0.181818181818182	1.00322945260778	0.567326558443356	0.866567931087949
GO:0030296	protein tyrosine kinase activator activity	6/3378	33/18639	0.181818181818182	1.00322945260778	0.567326558443356	0.866567931087949
GO:0008173	RNA methyltransferase activity	12/3378	67/18639	0.17910447761194	0.988255878688264	0.567957799807451	0.866567931087949
GO:0000062	fatty-acyl-CoA binding	3/3378	16/18639	0.1875	1.03458037300178	0.57499441438735	0.872197580846004
GO:0016675	oxidoreductase activity, acting on a heme group of donors	3/3378	16/18639	0.1875	1.03458037300178	0.57499441438735	0.872197580846004
GO:0017070	U6 snRNA binding	3/3378	16/18639	0.1875	1.03458037300178	0.57499441438735	0.872197580846004
GO:0043023	ribosomal large subunit binding	3/3378	16/18639	0.1875	1.03458037300178	0.57499441438735	0.872197580846004
GO:0097027	ubiquitin-protein transferase activator activity	3/3378	16/18639	0.1875	1.03458037300178	0.57499441438735	0.872197580846004
GO:0008970	phospholipase A1 activity	4/3378	22/18639	0.181818181818182	1.00322945260778	0.583631315649985	0.881195369979062
GO:0015377	chloride:monoatomic cation symporter activity	4/3378	22/18639	0.181818181818182	1.00322945260778	0.583631315649985	0.881195369979062
GO:0031683	G-protein beta/gamma-subunit complex binding	4/3378	22/18639	0.181818181818182	1.00322945260778	0.583631315649985	0.881195369979062
GO:0061133	endopeptidase activator activity	4/3378	22/18639	0.181818181818182	1.00322945260778	0.583631315649985	0.881195369979062
GO:0016298	lipase activity	23/3378	130/18639	0.176923076923077	0.976219428883727	0.586790684090053	0.884940117325623
GO:0015171	amino acid transmembrane transporter activity	18/3378	102/18639	0.176470588235294	0.973722704001672	0.590237890765168	0.88811734711067
GO:0050698	proteoglycan sulfotransferase activity	5/3378	28/18639	0.178571428571429	0.985314640954073	0.591387178407829	0.88811734711067
GO:0051119	sugar transmembrane transporter activity	5/3378	28/18639	0.178571428571429	0.985314640954073	0.591387178407829	0.88811734711067
GO:0003743	translation initiation factor activity	9/3378	51/18639	0.176470588235294	0.973722704001672	0.59225712070509	0.88811734711067
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	32/3378	181/18639	0.176795580110497	0.975515931817513	0.592305429500516	0.88811734711067
GO:0048029	monosaccharide binding	13/3378	74/18639	0.175675675675676	0.969336565695358	0.596845452521859	0.893896120271243
GO:0008175	tRNA methyltransferase activity	6/3378	34/18639	0.176470588235294	0.973722704001672	0.59849125182028	0.894305161836955
GO:0016831	carboxy-lyase activity	6/3378	34/18639	0.176470588235294	0.973722704001672	0.59849125182028	0.894305161836955
GO:0048306	calcium-dependent protein binding	14/3378	80/18639	0.175	0.965608348134991	0.603177339842461	0.900274998642299
GO:0015144	carbohydrate transmembrane transporter activity	7/3378	40/18639	0.175	0.965608348134991	0.605081089564876	0.901052182517752
GO:0050997	quaternary ammonium group binding	7/3378	40/18639	0.175	0.965608348134991	0.605081089564876	0.901052182517752
GO:0004659	prenyltransferase activity	3/3378	17/18639	0.176470588235294	0.973722704001672	0.618478595414501	0.902867138072436
GO:0008429	phosphatidylethanolamine binding	3/3378	17/18639	0.176470588235294	0.973722704001672	0.618478595414501	0.902867138072436
GO:0016805	dipeptidase activity	3/3378	17/18639	0.176470588235294	0.973722704001672	0.618478595414501	0.902867138072436
GO:0032977	membrane insertase activity	3/3378	17/18639	0.176470588235294	0.973722704001672	0.618478595414501	0.902867138072436
GO:0070402	NADPH binding	3/3378	17/18639	0.176470588235294	0.973722704001672	0.618478595414501	0.902867138072436
GO:1901567	fatty acid derivative binding	3/3378	17/18639	0.176470588235294	0.973722704001672	0.618478595414501	0.902867138072436
GO:0000099	sulfur amino acid transmembrane transporter activity	2/3378	11/18639	0.181818181818182	1.00322945260778	0.619295512555698	0.902867138072436
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	2/3378	11/18639	0.181818181818182	1.00322945260778	0.619295512555698	0.902867138072436
GO:0004016	adenylate cyclase activity	2/3378	11/18639	0.181818181818182	1.00322945260778	0.619295512555698	0.902867138072436
GO:0008046	axon guidance receptor activity	2/3378	11/18639	0.181818181818182	1.00322945260778	0.619295512555698	0.902867138072436
GO:0008503	benzodiazepine receptor activity	2/3378	11/18639	0.181818181818182	1.00322945260778	0.619295512555698	0.902867138072436
GO:0016594	glycine binding	2/3378	11/18639	0.181818181818182	1.00322945260778	0.619295512555698	0.902867138072436
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	2/3378	11/18639	0.181818181818182	1.00322945260778	0.619295512555698	0.902867138072436
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	2/3378	11/18639	0.181818181818182	1.00322945260778	0.619295512555698	0.902867138072436
GO:0019203	carbohydrate phosphatase activity	2/3378	11/18639	0.181818181818182	1.00322945260778	0.619295512555698	0.902867138072436
GO:0019215	intermediate filament binding	2/3378	11/18639	0.181818181818182	1.00322945260778	0.619295512555698	0.902867138072436
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	2/3378	11/18639	0.181818181818182	1.00322945260778	0.619295512555698	0.902867138072436
GO:1900750	oligopeptide binding	2/3378	11/18639	0.181818181818182	1.00322945260778	0.619295512555698	0.902867138072436
GO:0000295	adenine nucleotide transmembrane transporter activity	4/3378	23/18639	0.173913043478261	0.959610780755271	0.620851078828014	0.902867138072436
GO:0005283	amino acid:sodium symporter activity	4/3378	23/18639	0.173913043478261	0.959610780755271	0.620851078828014	0.902867138072436
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	4/3378	23/18639	0.173913043478261	0.959610780755271	0.620851078828014	0.902867138072436
GO:0099604	ligand-gated calcium channel activity	5/3378	29/18639	0.172413793103448	0.951338274024622	0.624392080460534	0.907004326466083
GO:0005343	organic acid:sodium symporter activity	6/3378	35/18639	0.171428571428571	0.94590205531591	0.628406977706282	0.910805664017003
GO:0034061	DNA polymerase activity	6/3378	35/18639	0.171428571428571	0.94590205531591	0.628406977706282	0.910805664017003
GO:0016874	ligase activity	29/3378	167/18639	0.173652694610778	0.958174237670308	0.632159628767911	0.915226662538431
GO:0051536	iron-sulfur cluster binding	13/3378	76/18639	0.171052631578947	0.943827708703375	0.637645270286517	0.922144047928227
GO:0004864	protein phosphatase inhibitor activity	9/3378	53/18639	0.169811320754717	0.936978451020476	0.641068065011545	0.924017354767747
GO:0016251	RNA polymerase II general transcription initiation factor activity	9/3378	53/18639	0.169811320754717	0.936978451020476	0.641068065011545	0.924017354767747
GO:0016860	intramolecular oxidoreductase activity	9/3378	53/18639	0.169811320754717	0.936978451020476	0.641068065011545	0.924017354767747
GO:0015215	nucleotide transmembrane transporter activity	5/3378	30/18639	0.166666666666667	0.919626998223801	0.655738614764102	0.926056184567362
GO:0022839	monoatomic ion-gated channel activity	5/3378	30/18639	0.166666666666667	0.919626998223801	0.655738614764102	0.926056184567362
GO:0031210	phosphatidylcholine binding	5/3378	30/18639	0.166666666666667	0.919626998223801	0.655738614764102	0.926056184567362
GO:0098918	structural constituent of synapse	5/3378	30/18639	0.166666666666667	0.919626998223801	0.655738614764102	0.926056184567362
GO:0001091	RNA polymerase II general transcription initiation factor binding	4/3378	24/18639	0.166666666666667	0.919626998223801	0.655896156981938	0.926056184567362
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	4/3378	24/18639	0.166666666666667	0.919626998223801	0.655896156981938	0.926056184567362
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	4/3378	24/18639	0.166666666666667	0.919626998223801	0.655896156981938	0.926056184567362
GO:0005315	phosphate transmembrane transporter activity	4/3378	24/18639	0.166666666666667	0.919626998223801	0.655896156981938	0.926056184567362
GO:0015149	hexose transmembrane transporter activity	4/3378	24/18639	0.166666666666667	0.919626998223801	0.655896156981938	0.926056184567362
GO:0030552	cAMP binding	4/3378	24/18639	0.166666666666667	0.919626998223801	0.655896156981938	0.926056184567362
GO:0055056	D-glucose transmembrane transporter activity	4/3378	24/18639	0.166666666666667	0.919626998223801	0.655896156981938	0.926056184567362
GO:0060229	lipase activator activity	4/3378	24/18639	0.166666666666667	0.919626998223801	0.655896156981938	0.926056184567362
GO:0004033	aldo-keto reductase (NADPH) activity	6/3378	36/18639	0.166666666666667	0.919626998223801	0.656982681469533	0.926056184567362
GO:0005484	SNAP receptor activity	6/3378	36/18639	0.166666666666667	0.919626998223801	0.656982681469533	0.926056184567362
GO:0045505	dynein intermediate chain binding	6/3378	36/18639	0.166666666666667	0.919626998223801	0.656982681469533	0.926056184567362
GO:0055106	ubiquitin-protein transferase regulator activity	6/3378	36/18639	0.166666666666667	0.919626998223801	0.656982681469533	0.926056184567362
GO:0051540	metal cluster binding	13/3378	77/18639	0.168831168831169	0.931570205992941	0.657224541170153	0.926056184567362
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	3/3378	18/18639	0.166666666666667	0.919626998223801	0.658828920256289	0.926056184567362
GO:0008525	phosphatidylcholine transporter activity	3/3378	18/18639	0.166666666666667	0.919626998223801	0.658828920256289	0.926056184567362
GO:0016854	racemase and epimerase activity	3/3378	18/18639	0.166666666666667	0.919626998223801	0.658828920256289	0.926056184567362
GO:0031690	adrenergic receptor binding	3/3378	18/18639	0.166666666666667	0.919626998223801	0.658828920256289	0.926056184567362
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	3/3378	18/18639	0.166666666666667	0.919626998223801	0.658828920256289	0.926056184567362
GO:1901611	phosphatidylglycerol binding	3/3378	18/18639	0.166666666666667	0.919626998223801	0.658828920256289	0.926056184567362
GO:0001540	amyloid-beta binding	14/3378	83/18639	0.168674698795181	0.930706841575895	0.661045116784911	0.927264511541824
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	8/3378	48/18639	0.166666666666667	0.919626998223801	0.661473541281854	0.927264511541824
GO:0017171	serine hydrolase activity	34/3378	198/18639	0.171717171717172	0.947494483018462	0.665075451864802	0.927264511541824
GO:0003995	acyl-CoA dehydrogenase activity	2/3378	12/18639	0.166666666666667	0.919626998223801	0.668228224357462	0.927264511541824
GO:0004000	adenosine deaminase activity	2/3378	12/18639	0.166666666666667	0.919626998223801	0.668228224357462	0.927264511541824
GO:0004526	ribonuclease P activity	2/3378	12/18639	0.166666666666667	0.919626998223801	0.668228224357462	0.927264511541824
GO:0005436	sodium:phosphate symporter activity	2/3378	12/18639	0.166666666666667	0.919626998223801	0.668228224357462	0.927264511541824
GO:0015166	polyol transmembrane transporter activity	2/3378	12/18639	0.166666666666667	0.919626998223801	0.668228224357462	0.927264511541824
GO:0042301	phosphate ion binding	2/3378	12/18639	0.166666666666667	0.919626998223801	0.668228224357462	0.927264511541824
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	2/3378	12/18639	0.166666666666667	0.919626998223801	0.668228224357462	0.927264511541824
GO:0097677	STAT family protein binding	2/3378	12/18639	0.166666666666667	0.919626998223801	0.668228224357462	0.927264511541824
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	2/3378	12/18639	0.166666666666667	0.919626998223801	0.668228224357462	0.927264511541824
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	7/3378	43/18639	0.162790697674419	0.898240323846503	0.684217027864513	0.948441263093043
GO:0008236	serine-type peptidase activity	33/3378	194/18639	0.170103092783505	0.938588379630477	0.68553674691463	0.949260766450332
GO:0016836	hydro-lyase activity	10/3378	61/18639	0.163934426229508	0.904551145793903	0.688196951963241	0.949588164902994
GO:0005262	calcium channel activity	22/3378	131/18639	0.16793893129771	0.926647051645357	0.688656384898962	0.949588164902994
GO:0005537	D-mannose binding	4/3378	25/18639	0.16	0.882841918294849	0.688688270017905	0.949588164902994
GO:0015296	monoatomic anion:monoatomic cation symporter activity	4/3378	25/18639	0.16	0.882841918294849	0.688688270017905	0.949588164902994
GO:0030246	carbohydrate binding	48/3378	280/18639	0.171428571428571	0.94590205531591	0.689737999234626	0.950030246303084
GO:0005229	intracellularly calcium-gated chloride channel activity	3/3378	19/18639	0.157894736842105	0.871225577264654	0.695995489404301	0.955618675125189
GO:0008301	DNA binding, bending	3/3378	19/18639	0.157894736842105	0.871225577264654	0.695995489404301	0.955618675125189
GO:0141147	intracellularly calcium-gated channel activity	3/3378	19/18639	0.157894736842105	0.871225577264654	0.695995489404301	0.955618675125189
GO:0033218	amide binding	42/3378	247/18639	0.17004048582996	0.938242929361935	0.702106753884693	0.962994842433427
GO:0032813	tumor necrosis factor receptor superfamily binding	8/3378	50/18639	0.16	0.882841918294849	0.707623674454126	0.963988932630293
GO:0019212	phosphatase inhibitor activity	9/3378	56/18639	0.160714285714286	0.886783176858665	0.707774375571453	0.963988932630293
GO:0019955	cytokine binding	24/3378	144/18639	0.166666666666667	0.919626998223801	0.70822021925443	0.963988932630293
GO:0002161	aminoacyl-tRNA editing activity	2/3378	13/18639	0.153846153846154	0.848886459898893	0.711934444810979	0.963988932630293
GO:0004465	lipoprotein lipase activity	2/3378	13/18639	0.153846153846154	0.848886459898893	0.711934444810979	0.963988932630293
GO:0008035	high-density lipoprotein particle binding	2/3378	13/18639	0.153846153846154	0.848886459898893	0.711934444810979	0.963988932630293
GO:0008253	5'-nucleotidase activity	2/3378	13/18639	0.153846153846154	0.848886459898893	0.711934444810979	0.963988932630293
GO:0019104	DNA N-glycosylase activity	2/3378	13/18639	0.153846153846154	0.848886459898893	0.711934444810979	0.963988932630293
GO:0045159	myosin II binding	2/3378	13/18639	0.153846153846154	0.848886459898893	0.711934444810979	0.963988932630293
GO:0070700	BMP receptor binding	2/3378	13/18639	0.153846153846154	0.848886459898893	0.711934444810979	0.963988932630293
GO:0071837	HMG box domain binding	2/3378	13/18639	0.153846153846154	0.848886459898893	0.711934444810979	0.963988932630293
GO:0140666	annealing activity	2/3378	13/18639	0.153846153846154	0.848886459898893	0.711934444810979	0.963988932630293
GO:0071813	lipoprotein particle binding	5/3378	32/18639	0.15625	0.862150310834814	0.713189049160094	0.963988932630293
GO:0071814	protein-lipid complex binding	5/3378	32/18639	0.15625	0.862150310834814	0.713189049160094	0.963988932630293
GO:0004519	endonuclease activity	21/3378	127/18639	0.165354330708661	0.912385840757472	0.714024213604359	0.964117668732103
GO:0004112	cyclic-nucleotide phosphodiesterase activity	4/3378	26/18639	0.153846153846154	0.848886459898893	0.719197552050742	0.968093399093096
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	4/3378	26/18639	0.153846153846154	0.848886459898893	0.719197552050742	0.968093399093096
GO:0015216	purine nucleotide transmembrane transporter activity	4/3378	26/18639	0.153846153846154	0.848886459898893	0.719197552050742	0.968093399093096
GO:0001972	retinoic acid binding	3/3378	20/18639	0.15	0.827664298401421	0.730005354149885	0.979605537031205
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	3/3378	20/18639	0.15	0.827664298401421	0.730005354149885	0.979605537031205
GO:0016505	peptidase activator activity involved in apoptotic process	3/3378	20/18639	0.15	0.827664298401421	0.730005354149885	0.979605537031205
GO:0015081	sodium ion transmembrane transporter activity	27/3378	164/18639	0.164634146341463	0.908412034830828	0.740108244768578	0.992140990672281
GO:0017022	myosin binding	12/3378	76/18639	0.157894736842105	0.871225577264654	0.745622098989113	0.99850523636466
GO:1901681	sulfur compound binding	46/3378	275/18639	0.167272727272727	0.92297109639916	0.750332922877076	1
GO:0005161	platelet-derived growth factor receptor binding	2/3378	14/18639	0.142857142857143	0.788251712763258	0.750700856479749	1
GO:0005313	L-glutamate transmembrane transporter activity	2/3378	14/18639	0.142857142857143	0.788251712763258	0.750700856479749	1
GO:0016530	metallochaperone activity	2/3378	14/18639	0.142857142857143	0.788251712763258	0.750700856479749	1
GO:0043176	amine binding	2/3378	14/18639	0.142857142857143	0.788251712763258	0.750700856479749	1
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	6/3378	40/18639	0.15	0.827664298401421	0.756892455737004	1
GO:0010314	phosphatidylinositol-5-phosphate binding	3/3378	21/18639	0.142857142857143	0.788251712763258	0.760944262325029	1
GO:0019200	carbohydrate kinase activity	3/3378	21/18639	0.142857142857143	0.788251712763258	0.760944262325029	1
GO:0036122	BMP binding	3/3378	21/18639	0.142857142857143	0.788251712763258	0.760944262325029	1
GO:0061891	calcium ion sensor activity	3/3378	21/18639	0.142857142857143	0.788251712763258	0.760944262325029	1
GO:1904047	S-adenosyl-L-methionine binding	3/3378	21/18639	0.142857142857143	0.788251712763258	0.760944262325029	1
GO:0008135	translation factor activity, RNA binding	13/3378	83/18639	0.156626506024096	0.864227781463331	0.761568069683923	1
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	5/3378	34/18639	0.147058823529412	0.81143558666806	0.763502245033763	1
GO:0046625	sphingolipid binding	4/3378	28/18639	0.142857142857143	0.788251712763258	0.773442374644609	1
GO:0180051	translation factor activity	13/3378	84/18639	0.154761904761905	0.85393935549353	0.776635952747717	1
GO:0008020	G protein-coupled photoreceptor activity	2/3378	15/18639	0.133333333333333	0.735701598579041	0.784881904126703	1
GO:0008252	nucleotidase activity	2/3378	15/18639	0.133333333333333	0.735701598579041	0.784881904126703	1
GO:0010181	FMN binding	2/3378	15/18639	0.133333333333333	0.735701598579041	0.784881904126703	1
GO:0034483	heparan sulfate sulfotransferase activity	2/3378	15/18639	0.133333333333333	0.735701598579041	0.784881904126703	1
GO:0045504	dynein heavy chain binding	2/3378	15/18639	0.133333333333333	0.735701598579041	0.784881904126703	1
GO:0050700	CARD domain binding	2/3378	15/18639	0.133333333333333	0.735701598579041	0.784881904126703	1
GO:0016881	acid-amino acid ligase activity	3/3378	22/18639	0.136363636363636	0.752422089455837	0.788941043378983	1
GO:0140784	metal ion sensor activity	3/3378	22/18639	0.136363636363636	0.752422089455837	0.788941043378983	1
GO:0016835	carbon-oxygen lyase activity	12/3378	79/18639	0.151898734177215	0.838141061672325	0.792383741009958	1
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	10/3378	67/18639	0.149253731343284	0.823546565573553	0.796655606471411	1
GO:0005416	amino acid:monoatomic cation symporter activity	4/3378	29/18639	0.137931034482759	0.761070619219697	0.79729042171406	1
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	4/3378	29/18639	0.137931034482759	0.761070619219697	0.79729042171406	1
GO:0008307	structural constituent of muscle	6/3378	42/18639	0.142857142857143	0.788251712763258	0.79806508830076	1
GO:0016859	cis-trans isomerase activity	6/3378	42/18639	0.142857142857143	0.788251712763258	0.79806508830076	1
GO:0031492	nucleosomal DNA binding	6/3378	42/18639	0.142857142857143	0.788251712763258	0.79806508830076	1
GO:0035254	glutamate receptor binding	7/3378	49/18639	0.142857142857143	0.788251712763258	0.809411814122632	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	3/3378	23/18639	0.130434782608696	0.719708085566453	0.814154538061628	1
GO:0016849	phosphorus-oxygen lyase activity	3/3378	23/18639	0.130434782608696	0.719708085566453	0.814154538061628	1
GO:0043274	phospholipase binding	3/3378	23/18639	0.130434782608696	0.719708085566453	0.814154538061628	1
GO:0099186	structural constituent of postsynapse	3/3378	23/18639	0.130434782608696	0.719708085566453	0.814154538061628	1
GO:0008296	3'-5'-DNA exonuclease activity	2/3378	16/18639	0.125	0.689720248667851	0.814865831232325	1
GO:0015378	sodium:chloride symporter activity	2/3378	16/18639	0.125	0.689720248667851	0.814865831232325	1
GO:0015385	sodium:proton antiporter activity	2/3378	16/18639	0.125	0.689720248667851	0.814865831232325	1
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	2/3378	16/18639	0.125	0.689720248667851	0.814865831232325	1
GO:0016722	oxidoreductase activity, acting on metal ions	2/3378	16/18639	0.125	0.689720248667851	0.814865831232325	1
GO:0022841	potassium ion leak channel activity	2/3378	16/18639	0.125	0.689720248667851	0.814865831232325	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	2/3378	16/18639	0.125	0.689720248667851	0.814865831232325	1
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	4/3378	30/18639	0.133333333333333	0.735701598579041	0.819067622783285	1
GO:0033612	receptor serine/threonine kinase binding	4/3378	30/18639	0.133333333333333	0.735701598579041	0.819067622783285	1
GO:0019001	guanyl nucleotide binding	66/3378	400/18639	0.165	0.910430728241563	0.820069523368463	1
GO:0032561	guanyl ribonucleotide binding	66/3378	400/18639	0.165	0.910430728241563	0.820069523368463	1
GO:0019003	GDP binding	11/3378	75/18639	0.146666666666667	0.809271758436945	0.822572868804192	1
GO:0008201	heparin binding	27/3378	172/18639	0.156976744186047	0.866160312280557	0.822932193872761	1
GO:0030551	cyclic nucleotide binding	5/3378	37/18639	0.135135135135135	0.745643512073352	0.825998730561398	1
GO:0005525	GTP binding	62/3378	378/18639	0.164021164021164	0.905029744283741	0.827367267930152	1
GO:0016248	channel inhibitor activity	6/3378	44/18639	0.136363636363636	0.752422089455837	0.833629816359254	1
GO:0030020	extracellular matrix structural constituent conferring tensile strength	6/3378	44/18639	0.136363636363636	0.752422089455837	0.833629816359254	1
GO:0004806	triacylglycerol lipase activity	3/3378	24/18639	0.125	0.689720248667851	0.83676287821587	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	3/3378	24/18639	0.125	0.689720248667851	0.83676287821587	1
GO:0046873	metal ion transmembrane transporter activity	74/3378	450/18639	0.164444444444444	0.90736530491415	0.840861001162026	1
GO:0004029	aldehyde dehydrogenase (NAD+) activity	2/3378	17/18639	0.117647058823529	0.649148469334448	0.841050796008034	1
GO:0004549	tRNA-specific ribonuclease activity	2/3378	17/18639	0.117647058823529	0.649148469334448	0.841050796008034	1
GO:0004550	nucleoside diphosphate kinase activity	2/3378	17/18639	0.117647058823529	0.649148469334448	0.841050796008034	1
GO:0008569	minus-end-directed microtubule motor activity	2/3378	17/18639	0.117647058823529	0.649148469334448	0.841050796008034	1
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	2/3378	17/18639	0.117647058823529	0.649148469334448	0.841050796008034	1
GO:0009881	photoreceptor activity	2/3378	17/18639	0.117647058823529	0.649148469334448	0.841050796008034	1
GO:0016018	cyclosporin A binding	2/3378	17/18639	0.117647058823529	0.649148469334448	0.841050796008034	1
GO:0030169	low-density lipoprotein particle binding	2/3378	17/18639	0.117647058823529	0.649148469334448	0.841050796008034	1
GO:0045125	bioactive lipid receptor activity	2/3378	17/18639	0.117647058823529	0.649148469334448	0.841050796008034	1
GO:0070492	oligosaccharide binding	2/3378	17/18639	0.117647058823529	0.649148469334448	0.841050796008034	1
GO:0141110	transporter inhibitor activity	6/3378	45/18639	0.133333333333333	0.735701598579041	0.849426335329758	1
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	3/3378	25/18639	0.12	0.662131438721137	0.856954870242865	1
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	5/3378	39/18639	0.128205128205128	0.707405383249078	0.859692559770638	1
GO:0003924	GTPase activity	53/3378	331/18639	0.16012084592145	0.883508717326794	0.860144068123995	1
GO:0015280	ligand-gated sodium channel activity	2/3378	18/18639	0.111111111111111	0.613084665482534	0.863828530477003	1
GO:0015373	monoatomic anion:sodium symporter activity	2/3378	18/18639	0.111111111111111	0.613084665482534	0.863828530477003	1
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	2/3378	18/18639	0.111111111111111	0.613084665482534	0.863828530477003	1
GO:0022851	GABA-gated chloride ion channel activity	2/3378	18/18639	0.111111111111111	0.613084665482534	0.863828530477003	1
GO:0070628	proteasome binding	2/3378	18/18639	0.111111111111111	0.613084665482534	0.863828530477003	1
GO:0004180	carboxypeptidase activity	6/3378	46/18639	0.130434782608696	0.719708085566453	0.863974654047631	1
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/3378	10/18639	0.1	0.551776198934281	0.864676984933887	1
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/3378	10/18639	0.1	0.551776198934281	0.864676984933887	1
GO:0004935	adrenergic receptor activity	1/3378	10/18639	0.1	0.551776198934281	0.864676984933887	1
GO:0008401	retinoic acid 4-hydroxylase activity	1/3378	10/18639	0.1	0.551776198934281	0.864676984933887	1
GO:0008519	ammonium channel activity	1/3378	10/18639	0.1	0.551776198934281	0.864676984933887	1
GO:0015643	toxic substance binding	1/3378	10/18639	0.1	0.551776198934281	0.864676984933887	1
GO:0016783	sulfurtransferase activity	1/3378	10/18639	0.1	0.551776198934281	0.864676984933887	1
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1/3378	10/18639	0.1	0.551776198934281	0.864676984933887	1
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/3378	10/18639	0.1	0.551776198934281	0.864676984933887	1
GO:0019531	oxalate transmembrane transporter activity	1/3378	10/18639	0.1	0.551776198934281	0.864676984933887	1
GO:0030957	Tat protein binding	1/3378	10/18639	0.1	0.551776198934281	0.864676984933887	1
GO:0031956	medium-chain fatty acid-CoA ligase activity	1/3378	10/18639	0.1	0.551776198934281	0.864676984933887	1
GO:0032052	bile acid binding	1/3378	10/18639	0.1	0.551776198934281	0.864676984933887	1
GO:0033204	ribonuclease P RNA binding	1/3378	10/18639	0.1	0.551776198934281	0.864676984933887	1
GO:0035256	G protein-coupled glutamate receptor binding	1/3378	10/18639	0.1	0.551776198934281	0.864676984933887	1
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	1/3378	10/18639	0.1	0.551776198934281	0.864676984933887	1
GO:0043208	glycosphingolipid binding	1/3378	10/18639	0.1	0.551776198934281	0.864676984933887	1
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/3378	10/18639	0.1	0.551776198934281	0.864676984933887	1
GO:0047429	nucleoside triphosphate diphosphatase activity	1/3378	10/18639	0.1	0.551776198934281	0.864676984933887	1
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/3378	10/18639	0.1	0.551776198934281	0.864676984933887	1
GO:0051378	serotonin binding	1/3378	10/18639	0.1	0.551776198934281	0.864676984933887	1
GO:0097177	mitochondrial ribosome binding	1/3378	10/18639	0.1	0.551776198934281	0.864676984933887	1
GO:0141109	transporter activator activity	1/3378	10/18639	0.1	0.551776198934281	0.864676984933887	1
GO:1990757	ubiquitin ligase activator activity	1/3378	10/18639	0.1	0.551776198934281	0.864676984933887	1
GO:1990763	arrestin family protein binding	1/3378	10/18639	0.1	0.551776198934281	0.864676984933887	1
GO:0005544	calcium-dependent phospholipid binding	7/3378	53/18639	0.132075471698113	0.728761017460371	0.868934526464716	1
GO:0033293	monocarboxylic acid binding	11/3378	79/18639	0.139240506329114	0.768295973199631	0.870263711866555	1
GO:0019956	chemokine binding	4/3378	33/18639	0.121212121212121	0.668819635071855	0.873053111897486	1
GO:0052689	carboxylic ester hydrolase activity	13/3378	92/18639	0.141304347826087	0.779683759363657	0.873446728459921	1
GO:0004521	RNA endonuclease activity	10/3378	73/18639	0.136986301369863	0.755857806759288	0.874511030584148	1
GO:0046982	protein heterodimerization activity	59/3378	369/18639	0.159891598915989	0.88224378691389	0.874525724177361	1
GO:0004435	phosphatidylinositol phospholipase C activity	3/3378	26/18639	0.115384615384615	0.63666484492417	0.874923216094011	1
GO:0004529	DNA exonuclease activity	3/3378	26/18639	0.115384615384615	0.63666484492417	0.874923216094011	1
GO:0120014	phospholipid transfer activity	3/3378	26/18639	0.115384615384615	0.63666484492417	0.874923216094011	1
GO:0016779	nucleotidyltransferase activity	20/3378	136/18639	0.147058823529412	0.81143558666806	0.876856329513109	1
GO:0099095	ligand-gated monoatomic anion channel activity	6/3378	47/18639	0.127659574468085	0.704395147575677	0.877336931909111	1
GO:0000049	tRNA binding	11/3378	80/18639	0.1375	0.758692273534636	0.880427016440414	1
GO:0004890	GABA-A receptor activity	2/3378	19/18639	0.105263157894737	0.580817051509769	0.883573594132615	1
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	2/3378	19/18639	0.105263157894737	0.580817051509769	0.883573594132615	1
GO:0022840	leak channel activity	2/3378	19/18639	0.105263157894737	0.580817051509769	0.883573594132615	1
GO:0022842	narrow pore channel activity	2/3378	19/18639	0.105263157894737	0.580817051509769	0.883573594132615	1
GO:0043395	heparan sulfate proteoglycan binding	2/3378	19/18639	0.105263157894737	0.580817051509769	0.883573594132615	1
GO:0070003	threonine-type peptidase activity	2/3378	19/18639	0.105263157894737	0.580817051509769	0.883573594132615	1
GO:0005536	D-glucose binding	1/3378	11/18639	0.0909090909090909	0.501614726303891	0.889215132171706	1
GO:0010854	adenylate cyclase regulator activity	1/3378	11/18639	0.0909090909090909	0.501614726303891	0.889215132171706	1
GO:0016176	superoxide-generating NADPH oxidase activator activity	1/3378	11/18639	0.0909090909090909	0.501614726303891	0.889215132171706	1
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	1/3378	11/18639	0.0909090909090909	0.501614726303891	0.889215132171706	1
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	1/3378	11/18639	0.0909090909090909	0.501614726303891	0.889215132171706	1
GO:0019206	nucleoside kinase activity	1/3378	11/18639	0.0909090909090909	0.501614726303891	0.889215132171706	1
GO:0042608	T cell receptor binding	1/3378	11/18639	0.0909090909090909	0.501614726303891	0.889215132171706	1
GO:0048407	platelet-derived growth factor binding	1/3378	11/18639	0.0909090909090909	0.501614726303891	0.889215132171706	1
GO:0050786	RAGE receptor binding	1/3378	11/18639	0.0909090909090909	0.501614726303891	0.889215132171706	1
GO:0070697	activin receptor binding	1/3378	11/18639	0.0909090909090909	0.501614726303891	0.889215132171706	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/3378	11/18639	0.0909090909090909	0.501614726303891	0.889215132171706	1
GO:0016879	ligase activity, forming carbon-nitrogen bonds	6/3378	48/18639	0.125	0.689720248667851	0.889577951914428	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	3/3378	27/18639	0.111111111111111	0.613084665482534	0.890859306922272	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	19/3378	132/18639	0.143939393939394	0.794223316647828	0.893310981667835	1
GO:0016408	C-acyltransferase activity	2/3378	20/18639	0.1	0.551776198934281	0.900636731908473	1
GO:0042288	MHC class I protein binding	2/3378	20/18639	0.1	0.551776198934281	0.900636731908473	1
GO:0030170	pyridoxal phosphate binding	7/3378	56/18639	0.125	0.689720248667851	0.902743582146327	1
GO:0003720	telomerase activity	1/3378	12/18639	0.0833333333333333	0.459813499111901	0.90930485106391	1
GO:0008603	cAMP-dependent protein kinase regulator activity	1/3378	12/18639	0.0833333333333333	0.459813499111901	0.90930485106391	1
GO:0015132	prostaglandin transmembrane transporter activity	1/3378	12/18639	0.0833333333333333	0.459813499111901	0.90930485106391	1
GO:0015269	calcium-activated potassium channel activity	1/3378	12/18639	0.0833333333333333	0.459813499111901	0.90930485106391	1
GO:0016208	AMP binding	1/3378	12/18639	0.0833333333333333	0.459813499111901	0.90930485106391	1
GO:0070679	inositol 1,4,5 trisphosphate binding	1/3378	12/18639	0.0833333333333333	0.459813499111901	0.90930485106391	1
GO:1990459	transferrin receptor binding	1/3378	12/18639	0.0833333333333333	0.459813499111901	0.90930485106391	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	17/3378	122/18639	0.139344262295082	0.768868473924817	0.91074016706545	1
GO:0008200	ion channel inhibitor activity	5/3378	43/18639	0.116279069767442	0.641600231318931	0.910818416607241	1
GO:0070279	vitamin B6 binding	7/3378	57/18639	0.12280701754386	0.677619893428064	0.91222262721954	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	4/3378	36/18639	0.111111111111111	0.613084665482534	0.912518045213594	1
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	4/3378	36/18639	0.111111111111111	0.613084665482534	0.912518045213594	1
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	4/3378	36/18639	0.111111111111111	0.613084665482534	0.912518045213594	1
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	4/3378	36/18639	0.111111111111111	0.613084665482534	0.912518045213594	1
GO:0005248	voltage-gated sodium channel activity	2/3378	21/18639	0.0952380952380952	0.525501141842172	0.915341202390941	1
GO:0008373	sialyltransferase activity	2/3378	21/18639	0.0952380952380952	0.525501141842172	0.915341202390941	1
GO:0009975	cyclase activity	2/3378	21/18639	0.0952380952380952	0.525501141842172	0.915341202390941	1
GO:0070182	DNA polymerase binding	2/3378	21/18639	0.0952380952380952	0.525501141842172	0.915341202390941	1
GO:0004181	metallocarboxypeptidase activity	3/3378	29/18639	0.103448275862069	0.570802964414773	0.917371521535769	1
GO:0016853	isomerase activity	26/3378	180/18639	0.144444444444444	0.797010065127294	0.920196167085059	1
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/3378	13/18639	0.0769230769230769	0.424443229949447	0.925752384918321	1
GO:0003964	RNA-directed DNA polymerase activity	1/3378	13/18639	0.0769230769230769	0.424443229949447	0.925752384918321	1
GO:0009982	pseudouridine synthase activity	1/3378	13/18639	0.0769230769230769	0.424443229949447	0.925752384918321	1
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/3378	13/18639	0.0769230769230769	0.424443229949447	0.925752384918321	1
GO:0030955	potassium ion binding	1/3378	13/18639	0.0769230769230769	0.424443229949447	0.925752384918321	1
GO:0039706	co-receptor binding	1/3378	13/18639	0.0769230769230769	0.424443229949447	0.925752384918321	1
GO:0071714	icosanoid transmembrane transporter activity	1/3378	13/18639	0.0769230769230769	0.424443229949447	0.925752384918321	1
GO:0089720	caspase binding	1/3378	13/18639	0.0769230769230769	0.424443229949447	0.925752384918321	1
GO:0016829	lyase activity	29/3378	200/18639	0.145	0.800075488454707	0.926863734834712	1
GO:0005200	structural constituent of cytoskeleton	15/3378	112/18639	0.133928571428571	0.738985980715554	0.927726546490765	1
GO:0005243	gap junction channel activity	2/3378	22/18639	0.0909090909090909	0.501614726303891	0.927981218292137	1
GO:0030021	extracellular matrix structural constituent conferring compression resistance	2/3378	22/18639	0.0909090909090909	0.501614726303891	0.927981218292137	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	6/3378	52/18639	0.115384615384615	0.63666484492417	0.928654661927952	1
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	7/3378	59/18639	0.11864406779661	0.654649727549147	0.928813003329472	1
GO:0004252	serine-type endopeptidase activity	25/3378	176/18639	0.142045454545455	0.783773009849831	0.930697056004799	1
GO:0005501	retinoid binding	4/3378	38/18639	0.105263157894737	0.580817051509769	0.932347778981861	1
GO:0019840	isoprenoid binding	4/3378	38/18639	0.105263157894737	0.580817051509769	0.932347778981861	1
GO:0005246	calcium channel regulator activity	6/3378	53/18639	0.113207547169811	0.624652300680318	0.936278509008365	1
GO:0008146	sulfotransferase activity	6/3378	53/18639	0.113207547169811	0.624652300680318	0.936278509008365	1
GO:0005164	tumor necrosis factor receptor binding	3/3378	31/18639	0.0967741935483871	0.533976966710594	0.937874548928351	1
GO:0047499	calcium-independent phospholipase A2 activity	3/3378	31/18639	0.0967741935483871	0.533976966710594	0.937874548928351	1
GO:0016917	GABA receptor activity	2/3378	23/18639	0.0869565217391304	0.479805390377635	0.938821854504567	1
GO:0005347	ATP transmembrane transporter activity	1/3378	14/18639	0.0714285714285714	0.394125856381629	0.939217887105903	1
GO:0008392	arachidonate epoxygenase activity	1/3378	14/18639	0.0714285714285714	0.394125856381629	0.939217887105903	1
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	4/3378	39/18639	0.102564102564103	0.565924306599262	0.940651232606	1
GO:0047498	calcium-dependent phospholipase A2 activity	3/3378	32/18639	0.09375	0.517290186500888	0.946258173315809	1
GO:0019957	C-C chemokine binding	2/3378	24/18639	0.0833333333333333	0.459813499111901	0.948099943258084	1
GO:0005201	extracellular matrix structural constituent	23/3378	168/18639	0.136904761904762	0.755407891398122	0.949228580649184	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/3378	15/18639	0.0666666666666667	0.36785079928952	0.950241885890132	1
GO:0005523	tropomyosin binding	1/3378	15/18639	0.0666666666666667	0.36785079928952	0.950241885890132	1
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	1/3378	15/18639	0.0666666666666667	0.36785079928952	0.950241885890132	1
GO:0017081	chloride channel regulator activity	1/3378	15/18639	0.0666666666666667	0.36785079928952	0.950241885890132	1
GO:0030553	cGMP binding	1/3378	15/18639	0.0666666666666667	0.36785079928952	0.950241885890132	1
GO:0031005	filamin binding	1/3378	15/18639	0.0666666666666667	0.36785079928952	0.950241885890132	1
GO:0031386	protein tag activity	1/3378	15/18639	0.0666666666666667	0.36785079928952	0.950241885890132	1
GO:0047372	monoacylglycerol lipase activity	1/3378	15/18639	0.0666666666666667	0.36785079928952	0.950241885890132	1
GO:0055105	ubiquitin-protein transferase inhibitor activity	1/3378	15/18639	0.0666666666666667	0.36785079928952	0.950241885890132	1
GO:0140161	monocarboxylate:sodium symporter activity	1/3378	15/18639	0.0666666666666667	0.36785079928952	0.950241885890132	1
GO:0141047	molecular tag activity	1/3378	15/18639	0.0666666666666667	0.36785079928952	0.950241885890132	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	8/3378	70/18639	0.114285714285714	0.630601370210606	0.953593419900063	1
GO:0170055	lipid transmembrane transporter activity	6/3378	56/18639	0.107142857142857	0.591188784572444	0.954982340923169	1
GO:0015271	outward rectifier potassium channel activity	2/3378	25/18639	0.08	0.441420959147425	0.956025601781147	1
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	1/3378	16/18639	0.0625	0.344860124333925	0.959266956200653	1
GO:0005149	interleukin-1 receptor binding	1/3378	16/18639	0.0625	0.344860124333925	0.959266956200653	1
GO:0008142	oxysterol binding	1/3378	16/18639	0.0625	0.344860124333925	0.959266956200653	1
GO:0008391	arachidonate monooxygenase activity	1/3378	16/18639	0.0625	0.344860124333925	0.959266956200653	1
GO:0055102	lipase inhibitor activity	1/3378	16/18639	0.0625	0.344860124333925	0.959266956200653	1
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	3/3378	34/18639	0.0882352941176471	0.486861352000836	0.959957916745866	1
GO:0051427	hormone receptor binding	3/3378	34/18639	0.0882352941176471	0.486861352000836	0.959957916745866	1
GO:0070851	growth factor receptor binding	18/3378	139/18639	0.129496402877698	0.714530329555184	0.960173850874968	1
GO:0008198	ferrous iron binding	2/3378	26/18639	0.0769230769230769	0.424443229949447	0.962784133921742	1
GO:0030247	polysaccharide binding	2/3378	26/18639	0.0769230769230769	0.424443229949447	0.962784133921742	1
GO:0004623	phospholipase A2 activity	3/3378	35/18639	0.0857142857142857	0.472951027657955	0.965506318809473	1
GO:0005272	sodium channel activity	5/3378	51/18639	0.0980392156862745	0.540957057778707	0.966626502489488	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/3378	17/18639	0.0588235294117647	0.324574234667224	0.966655466212691	1
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/3378	17/18639	0.0588235294117647	0.324574234667224	0.966655466212691	1
GO:0030548	acetylcholine receptor regulator activity	1/3378	17/18639	0.0588235294117647	0.324574234667224	0.966655466212691	1
GO:0031489	myosin V binding	1/3378	17/18639	0.0588235294117647	0.324574234667224	0.966655466212691	1
GO:0036041	long-chain fatty acid binding	1/3378	17/18639	0.0588235294117647	0.324574234667224	0.966655466212691	1
GO:0045236	CXCR chemokine receptor binding	1/3378	17/18639	0.0588235294117647	0.324574234667224	0.966655466212691	1
GO:0070888	E-box binding	6/3378	59/18639	0.101694915254237	0.561128337899269	0.96856954463989	1
GO:0003746	translation elongation factor activity	1/3378	18/18639	0.0555555555555556	0.306542332741267	0.972704109491261	1
GO:0005372	water transmembrane transporter activity	1/3378	18/18639	0.0555555555555556	0.306542332741267	0.972704109491261	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/3378	18/18639	0.0555555555555556	0.306542332741267	0.972704109491261	1
GO:0032393	MHC class I receptor activity	1/3378	18/18639	0.0555555555555556	0.306542332741267	0.972704109491261	1
GO:0099602	neurotransmitter receptor regulator activity	1/3378	18/18639	0.0555555555555556	0.306542332741267	0.972704109491261	1
GO:0141108	transporter regulator activity	22/3378	170/18639	0.129411764705882	0.714063316267893	0.972806223613223	1
GO:0051537	2 iron, 2 sulfur cluster binding	2/3378	28/18639	0.0714285714285714	0.394125856381629	0.973429564796015	1
GO:0042605	peptide antigen binding	4/3378	45/18639	0.0888888888888889	0.490467732386027	0.973747231064896	1
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	1/3378	19/18639	0.0526315789473684	0.290408525754885	0.977655804788964	1
GO:0016918	retinal binding	1/3378	19/18639	0.0526315789473684	0.290408525754885	0.977655804788964	1
GO:0034987	immunoglobulin receptor binding	1/3378	19/18639	0.0526315789473684	0.290408525754885	0.977655804788964	1
GO:0042834	peptidoglycan binding	1/3378	19/18639	0.0526315789473684	0.290408525754885	0.977655804788964	1
GO:0099106	ion channel regulator activity	20/3378	160/18639	0.125	0.689720248667851	0.978901955584112	1
GO:0016782	transferase activity, transferring sulphur-containing groups	7/3378	70/18639	0.1	0.551776198934281	0.979504506493915	1
GO:0005504	fatty acid binding	4/3378	47/18639	0.0851063829787234	0.469596765050452	0.9801986576827	1
GO:0016247	channel regulator activity	21/3378	168/18639	0.125	0.689720248667851	0.981135189014538	1
GO:0001614	purinergic nucleotide receptor activity	1/3378	20/18639	0.05	0.27588809946714	0.981709440203726	1
GO:0010851	cyclase regulator activity	1/3378	20/18639	0.05	0.27588809946714	0.981709440203726	1
GO:0016502	nucleotide receptor activity	1/3378	20/18639	0.05	0.27588809946714	0.981709440203726	1
GO:0030627	pre-mRNA 5'-splice site binding	1/3378	20/18639	0.05	0.27588809946714	0.981709440203726	1
GO:0004857	enzyme inhibitor activity	60/3378	416/18639	0.144230769230769	0.795831056155212	0.981809690676952	1
GO:0016209	antioxidant activity	9/3378	86/18639	0.104651162790698	0.577440208187038	0.982304523003216	1
GO:0005539	glycosaminoglycan binding	32/3378	242/18639	0.132231404958678	0.729621420078388	0.983962426880734	1
GO:0004601	peroxidase activity	5/3378	57/18639	0.087719298245614	0.484014209591474	0.984878570184818	1
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	15/3378	130/18639	0.115384615384615	0.63666484492417	0.984961145575598	1
GO:0001846	opsonin binding	1/3378	21/18639	0.0476190476190476	0.262750570921086	0.985027852094366	1
GO:0051428	peptide hormone receptor binding	1/3378	21/18639	0.0476190476190476	0.262750570921086	0.985027852094366	1
GO:0004867	serine-type endopeptidase inhibitor activity	10/3378	95/18639	0.105263157894737	0.580817051509769	0.985397141648964	1
GO:0001530	lipopolysaccharide binding	3/3378	41/18639	0.0731707317073171	0.403738682147035	0.986247222822871	1
GO:0004812	aminoacyl-tRNA ligase activity	3/3378	41/18639	0.0731707317073171	0.403738682147035	0.986247222822871	1
GO:0016875	ligase activity, forming carbon-oxygen bonds	3/3378	41/18639	0.0731707317073171	0.403738682147035	0.986247222822871	1
GO:0042287	MHC protein binding	3/3378	41/18639	0.0731707317073171	0.403738682147035	0.986247222822871	1
GO:0140101	catalytic activity, acting on a tRNA	16/3378	139/18639	0.115107913669065	0.635138070715719	0.987654528907769	1
GO:0008649	rRNA methyltransferase activity	1/3378	22/18639	0.0454545454545455	0.250807363151946	0.9877443584659	1
GO:0033691	sialic acid binding	1/3378	22/18639	0.0454545454545455	0.250807363151946	0.9877443584659	1
GO:0015459	potassium channel regulator activity	5/3378	59/18639	0.0847457627118644	0.46760694824939	0.98848644948058	1
GO:0019239	deaminase activity	2/3378	33/18639	0.0606060606060606	0.334409817535928	0.988736288754062	1
GO:0005245	voltage-gated calcium channel activity	3/3378	43/18639	0.0697674418604651	0.384960138791359	0.989960428362946	1
GO:0004602	glutathione peroxidase activity	1/3378	23/18639	0.0434782608695652	0.239902695188818	0.989968108645961	1
GO:0005212	structural constituent of eye lens	1/3378	23/18639	0.0434782608695652	0.239902695188818	0.989968108645961	1
GO:0016493	C-C chemokine receptor activity	1/3378	23/18639	0.0434782608695652	0.239902695188818	0.989968108645961	1
GO:0031681	G-protein beta-subunit binding	1/3378	23/18639	0.0434782608695652	0.239902695188818	0.989968108645961	1
GO:0140102	catalytic activity, acting on a rRNA	1/3378	23/18639	0.0434782608695652	0.239902695188818	0.989968108645961	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	2/3378	34/18639	0.0588235294117647	0.324574234667224	0.990534937004574	1
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	5/3378	61/18639	0.0819672131147541	0.452275572896951	0.991267896844985	1
GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	1/3378	24/18639	0.0416666666666667	0.22990674955595	0.991788463662825	1
GO:0061134	peptidase regulator activity	28/3378	226/18639	0.123893805309735	0.683616529653091	0.99256129420271	1
GO:0005251	delayed rectifier potassium channel activity	1/3378	25/18639	0.04	0.220710479573712	0.993278582907895	1
GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	1/3378	25/18639	0.04	0.220710479573712	0.993278582907895	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	2/3378	36/18639	0.0555555555555556	0.306542332741267	0.993329963447844	1
GO:0003730	mRNA 3'-UTR binding	33/3378	262/18639	0.125954198473282	0.694985288734017	0.994079466851636	1
GO:0005506	iron ion binding	17/3378	154/18639	0.11038961038961	0.609103596226154	0.994282825504955	1
GO:0022829	wide pore channel activity	2/3378	37/18639	0.0540540540540541	0.298257404829341	0.994406043081403	1
GO:0023023	MHC protein complex binding	2/3378	37/18639	0.0540540540540541	0.298257404829341	0.994406043081403	1
GO:0004896	cytokine receptor activity	9/3378	96/18639	0.09375	0.517290186500888	0.994446641012468	1
GO:0001637	G protein-coupled chemoattractant receptor activity	1/3378	26/18639	0.0384615384615385	0.212221614974723	0.994498360867341	1
GO:0004950	chemokine receptor activity	1/3378	26/18639	0.0384615384615385	0.212221614974723	0.994498360867341	1
GO:0038187	pattern recognition receptor activity	3/3378	48/18639	0.0625	0.344860124333925	0.995496645363152	1
GO:0004364	glutathione transferase activity	1/3378	27/18639	0.037037037037037	0.204361555160845	0.995496831666789	1
GO:0005104	fibroblast growth factor receptor binding	1/3378	27/18639	0.037037037037037	0.204361555160845	0.995496831666789	1
GO:0023026	MHC class II protein complex binding	1/3378	27/18639	0.037037037037037	0.204361555160845	0.995496831666789	1
GO:0016866	intramolecular transferase activity	1/3378	28/18639	0.0357142857142857	0.197062928190815	0.996314137847188	1
GO:0071855	neuropeptide receptor binding	2/3378	40/18639	0.05	0.27588809946714	0.996711523058822	1
GO:0048019	receptor antagonist activity	1/3378	30/18639	0.0333333333333333	0.18392539964476	0.997530748194906	1
GO:0070566	adenylyltransferase activity	1/3378	30/18639	0.0333333333333333	0.18392539964476	0.997530748194906	1
GO:0042056	chemoattractant activity	2/3378	42/18639	0.0476190476190476	0.262750570921086	0.997698353248543	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/3378	32/18639	0.03125	0.172430062166963	0.998345864934902	1
GO:0046906	tetrapyrrole binding	15/3378	152/18639	0.0986842105263158	0.544515985790408	0.998421314616086	1
GO:0042923	neuropeptide binding	1/3378	33/18639	0.0303030303030303	0.167204908767964	0.998646164190553	1
GO:0019843	rRNA binding	4/3378	65/18639	0.0615384615384615	0.339554583959557	0.998678944462307	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	3/3378	56/18639	0.0535714285714286	0.295594392286222	0.998796576820117	1
GO:0005216	monoatomic ion channel activity	58/3378	448/18639	0.129464285714286	0.714353114691703	0.998871172961474	1
GO:0016229	steroid dehydrogenase activity	1/3378	35/18639	0.0285714285714286	0.157650342552652	0.999093139424293	1
GO:0020037	heme binding	13/3378	142/18639	0.0915492957746479	0.505147224376454	0.999108996707894	1
GO:0015079	potassium ion transmembrane transporter activity	15/3378	160/18639	0.09375	0.517290186500888	0.999354608770407	1
GO:0005126	cytokine receptor binding	31/3378	275/18639	0.112727272727273	0.622002260616825	0.999354789149864	1
GO:0030280	structural constituent of skin epidermis	1/3378	37/18639	0.027027027027027	0.14912870241467	0.999392572664872	1
GO:0001664	G protein-coupled receptor binding	34/3378	297/18639	0.114478114478114	0.631662988678975	0.999425346124993	1
GO:0061135	endopeptidase regulator activity	18/3378	184/18639	0.0978260869565217	0.53978106417484	0.999457244559727	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	4/3378	73/18639	0.0547945205479452	0.302343122703715	0.999631448892551	1
GO:0022824	transmitter-gated monoatomic ion channel activity	3/3378	63/18639	0.0476190476190476	0.262750570921086	0.999631841322745	1
GO:0022835	transmitter-gated channel activity	3/3378	63/18639	0.0476190476190476	0.262750570921086	0.999631841322745	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	2/3378	53/18639	0.0377358490566038	0.208217433560106	0.999686221493171	1
GO:0008227	G protein-coupled amine receptor activity	1/3378	41/18639	0.024390243902439	0.134579560715678	0.999727516765013	1
GO:0099094	ligand-gated monoatomic cation channel activity	11/3378	136/18639	0.0808823529411765	0.446289572667433	0.999730392069302	1
GO:0005261	monoatomic cation channel activity	39/3378	341/18639	0.114369501466276	0.631063687930702	0.999752995332362	1
GO:0004866	endopeptidase inhibitor activity	14/3378	161/18639	0.0869565217391304	0.479805390377635	0.999767324024651	1
GO:0030414	peptidase inhibitor activity	15/3378	169/18639	0.0887573964497041	0.489742188403208	0.999773522816404	1
GO:0030547	signaling receptor inhibitor activity	1/3378	44/18639	0.0227272727272727	0.125403681575973	0.999850662298058	1
GO:0098960	postsynaptic neurotransmitter receptor activity	3/3378	69/18639	0.0434782608695652	0.239902695188818	0.999868959271084	1
GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	1/3378	46/18639	0.0217391304347826	0.119951347594409	0.999899993093188	1
GO:0008188	neuropeptide receptor activity	1/3378	48/18639	0.0208333333333333	0.114953374777975	0.999933031621507	1
GO:0022834	ligand-gated channel activity	16/3378	188/18639	0.0851063829787234	0.469596765050452	0.999940975377874	1
GO:0048020	CCR chemokine receptor binding	1/3378	50/18639	0.02	0.110355239786856	0.999955157602424	1
GO:0022832	voltage-gated channel activity	14/3378	175/18639	0.08	0.441420959147425	0.99995908455327	1
GO:0015276	ligand-gated monoatomic ion channel activity	15/3378	186/18639	0.0806451612903226	0.444980805592162	0.999971779561433	1
GO:0005244	voltage-gated monoatomic ion channel activity	13/3378	173/18639	0.0751445086705202	0.414629513650037	0.99998168820955	1
GO:0042379	chemokine receptor binding	2/3378	72/18639	0.0277777777777778	0.153271166370634	0.999990772748425	1
GO:0004497	monooxygenase activity	5/3378	106/18639	0.0471698113207547	0.260271791950132	0.999991439068027	1
GO:0030594	neurotransmitter receptor activity	4/3378	97/18639	0.0412371134020619	0.227536576880116	0.999993287036174	1
GO:0140375	immune receptor activity	10/3378	156/18639	0.0641025641025641	0.353702691624539	0.999994524886223	1
GO:0022836	gated channel activity	30/3378	318/18639	0.0943396226415094	0.520543583900265	0.999995746451107	1
GO:0005267	potassium channel activity	6/3378	124/18639	0.0483870967741935	0.266988483355297	0.999997645656589	1
GO:0008083	growth factor activity	10/3378	162/18639	0.0617283950617284	0.340602591934741	0.999997711295345	1
GO:0005249	voltage-gated potassium channel activity	3/3378	98/18639	0.0306122448979592	0.168911081306412	0.99999924533997	1
GO:0005179	hormone activity	6/3378	132/18639	0.0454545454545455	0.250807363151946	0.999999361317461	1
GO:0003735	structural constituent of ribosome	10/3378	175/18639	0.0571428571428571	0.315300685105303	0.999999668169095	1
GO:0022843	voltage-gated monoatomic cation channel activity	6/3378	143/18639	0.041958041958042	0.231514489063335	0.999999896836436	1
GO:0003823	antigen binding	8/3378	174/18639	0.0459770114942529	0.253690206406566	0.999999981228578	1
GO:0008528	G protein-coupled peptide receptor activity	3/3378	122/18639	0.0245901639344262	0.135682671869085	0.999999990785162	1
GO:0001653	peptide receptor activity	3/3378	128/18639	0.0234375	0.129322546625222	0.999999996978284	1
GO:0005125	cytokine activity	8/3378	234/18639	0.0341880341880342	0.188641435533087	0.999999999999202	1
GO:0045182	translation regulator activity	17/3378	356/18639	0.047752808988764	0.26348863432255	0.999999999999992	1
GO:0030371	translation repressor activity	12/3378	329/18639	0.0364741641337386	0.201255756450194	1	1