category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore NA NA hsa04518 Integrin signaling 4/22 154/9376 11.0696576151122 FN1/FBN1/EGFR/MET 6.11027562992124 Organismal Systems Immune system hsa04610 Complement and coagulation cascades 3/22 88/9376 14.5289256198347 F13A1/SERPINE2/F5 6.18360639471227 Human Diseases Infectious disease: viral hsa05171 Coronavirus disease - COVID-19 4/22 238/9376 7.16271963330787 F13A1/EGFR/CYBB/NRP1 4.67017987353865 Environmental Information Processing Signal transduction hsa04010 MAPK signaling pathway 4/22 300/9376 5.68242424242424 EGFR/MET/CSF1R/MEF2C 3.99744446687353 Cellular Processes Transport and catabolism hsa04145 Phagosome 3/22 155/9376 8.24868035190616 CD36/CYBB/MRC1 4.41300157866413 Human Diseases Infectious disease: parasitic hsa05144 Malaria 2/22 50/9376 17.0472727272727 CD36/MET 5.51742992510359 Organismal Systems Digestive system hsa04979 Cholesterol metabolism 2/22 52/9376 16.3916083916084 CD36/LRP2 5.39737807200421 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 4/22 362/9376 4.70919136112506 FN1/EGFR/MET/CSF1R 3.49038267131402 Human Diseases Cancer: overview hsa05202 Transcriptional misregulation in cancer 3/22 201/9376 6.36092265943012 MET/CSF1R/MEF2C 3.72591402937807 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 3/22 203/9376 6.29825347066726 FN1/EGFR/MET 3.7010363393022 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 3/22 204/9376 6.26737967914438 FN1/EGFR/MET 3.68872246333043 Human Diseases Infectious disease: bacterial hsa05120 Epithelial cell signaling in Helicobacter pylori infection 2/22 71/9376 12.0051216389245 EGFR/MET 4.51402675239033 Human Diseases Cancer: overview hsa05230 Central carbon metabolism in cancer 2/22 71/9376 12.0051216389245 EGFR/MET 4.51402675239033 Human Diseases Cancer: specific types hsa05218 Melanoma 2/22 73/9376 11.6762141967621 EGFR/MET 4.44084375978617 Human Diseases Cancer: specific types hsa05223 Non-small cell lung cancer 2/22 73/9376 11.6762141967621 EGFR/MET 4.44084375978617 Environmental Information Processing Signal transduction hsa04015 Rap1 signaling pathway 3/22 212/9376 6.03087478559177 EGFR/MET/CSF1R 3.5930825429387 Human Diseases Infectious disease: bacterial hsa05100 Bacterial invasion of epithelial cells 2/22 78/9376 10.9277389277389 FN1/MET 4.26973748389997 Human Diseases Drug resistance: antineoplastic hsa01521 EGFR tyrosine kinase inhibitor resistance 2/22 80/9376 10.6545454545455 EGFR/MET 4.20559127857459 Cellular Processes Cell motility hsa04820 Cytoskeleton in muscle cells 3/22 233/9376 5.48731954740538 FN1/FBN2/FBN1 3.36371269058754 Environmental Information Processing Signal transduction hsa04014 Ras signaling pathway 3/22 238/9376 5.3720397249809 EGFR/MET/CSF1R 3.31318202755197 Environmental Information Processing Signaling molecules and interaction hsa04512 ECM-receptor interaction 2/22 89/9376 9.57711950970378 FN1/CD36 3.94273000321574 Cellular Processes Cellular community - eukaryotes hsa04520 Adherens junction 2/22 93/9376 9.16520039100684 EGFR/MET 3.83762418628455 Organismal Systems Immune system hsa04640 Hematopoietic cell lineage 2/22 100/9376 8.52363636363636 CD36/CSF1R 3.6681384785882 Human Diseases Endocrine and metabolic disease hsa04933 AGE-RAGE signaling pathway in diabetic complications 2/22 101/9376 8.43924392439244 FN1/CYBB 3.64527941013998 Environmental Information Processing Signal transduction hsa04066 HIF-1 signaling pathway 2/22 110/9376 7.74876033057851 EGFR/CYBB 3.45280852867001 Organismal Systems Endocrine system hsa04928 Parathyroid hormone synthesis, secretion and action 2/22 115/9376 7.41185770750988 EGFR/MEF2C 3.35507435781352 Human Diseases Cancer: specific types hsa05226 Gastric cancer 2/22 150/9376 5.68242424242424 EGFR/MET 2.80354776558429 Organismal Systems Endocrine system hsa04921 Oxytocin signaling pathway 2/22 154/9376 5.53482880755608 EGFR/MEF2C 2.75173744806278 Cellular Processes Transport and catabolism hsa04148 Efferocytosis 2/22 157/9376 5.42906774753909 CD36/STAB1 2.71405433480466 Human Diseases Cancer: specific types hsa05225 Hepatocellular carcinoma 2/22 170/9376 5.01390374331551 EGFR/MET 2.56126328925285 Organismal Systems Development and regeneration hsa04360 Axon guidance 2/22 184/9376 4.63241106719368 NRP1/MET 2.41322152110875 Organismal Systems Immune system hsa04621 NOD-like receptor signaling pathway 2/22 187/9376 4.55809431210501 CYBB/NAMPT 2.3834301499769 Human Diseases Immune disease hsa05310 Asthma 1/22 32/9376 13.3181818181818 PRG2 3.38495952572438 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 2/22 205/9376 4.15787139689579 CD36/CYBB 2.21697767194379 Metabolism Metabolism of cofactors and vitamins hsa00760 Nicotinate and nicotinamide metabolism 1/22 38/9376 11.2153110047847 NAMPT 3.0599529766893 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 2/22 216/9376 3.94612794612795 CD36/CYBB 2.12436451421755 Human Diseases Cancer: specific types hsa05219 Bladder cancer 1/22 41/9376 10.3946784922395 EGFR 2.92358001965837 Cellular Processes Cell growth and death hsa04216 Ferroptosis 1/22 42/9376 10.1471861471861 CYBB 2.88122092307246 Organismal Systems Digestive system hsa04975 Fat digestion and absorption 1/22 43/9376 9.91120507399577 CD36 2.84026151296422 Human Diseases Cancer: overview hsa05208 Chemical carcinogenesis - reactive oxygen species 2/22 227/9376 3.75490588706448 EGFR/MET 2.03765745485342 Cellular Processes Cell motility hsa04810 Regulation of actin cytoskeleton 2/22 232/9376 3.67398119122257 FN1/EGFR 2.00001166043053 NA NA hsa03272 Virion - Hepatitis viruses 1/22 48/9376 8.87878787878788 EGFR 2.65389694121851 Metabolism Lipid metabolism hsa00565 Ether lipid metabolism 1/22 51/9376 8.35650623885918 ENPP2 2.55464507801365 Cellular Processes Transport and catabolism hsa04144 Endocytosis 2/22 250/9376 3.40945454545455 DAB2/EGFR 1.87260770355437 Environmental Information Processing Signal transduction hsa04020 Calcium signaling pathway 2/22 254/9376 3.35576234788833 EGFR/MET 1.84587206082217 Environmental Information Processing Signal transduction hsa04340 Hedgehog signaling pathway 1/22 56/9376 7.61038961038961 LRP2 2.40608746360585 Human Diseases Cancer: specific types hsa05213 Endometrial cancer 1/22 59/9376 7.22342064714946 EGFR 2.32549500101872 Human Diseases Cancer: specific types hsa05221 Acute myeloid leukemia 1/22 68/9376 6.26737967914438 CSF1R 2.11406915049791 Organismal Systems Endocrine system hsa04920 Adipocytokine signaling pathway 1/22 70/9376 6.08831168831169 CD36 2.0722373550555 Human Diseases Cancer: specific types hsa05211 Renal cell carcinoma 1/22 70/9376 6.08831168831169 MET 2.0722373550555 Organismal Systems Endocrine system hsa04918 Thyroid hormone synthesis 1/22 75/9376 5.68242424242424 LRP2 1.97439873876383 Organismal Systems Endocrine system hsa03320 PPAR signaling pathway 1/22 76/9376 5.60765550239234 CD36 1.9558863631216 Human Diseases Cancer: specific types hsa05214 Glioma 1/22 76/9376 5.60765550239234 EGFR 1.9558863631216 Human Diseases Cancer: specific types hsa05212 Pancreatic cancer 1/22 77/9376 5.53482880755608 EGFR 1.93769951870007 Human Diseases Infectious disease: parasitic hsa05140 Leishmaniasis 1/22 78/9376 5.46386946386946 CYBB 1.91982796000668 Human Diseases Cancer: overview hsa05206 MicroRNAs in cancer 2/22 323/9376 2.63889670700816 EGFR/MET 1.45363335402749 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 2/22 333/9376 2.55965055965056 FN1/EGFR 1.40537250466529 Environmental Information Processing Signal transduction hsa04012 ErbB signaling pathway 1/22 86/9376 4.95560253699789 EGFR 1.78711422294197 Organismal Systems Sensory system hsa04742 Taste transduction 1/22 86/9376 4.95560253699789 SCN9A 1.78711422294197 Human Diseases Cancer: specific types hsa05210 Colorectal cancer 1/22 87/9376 4.89864158829676 EGFR 1.77168599429387 Cellular Processes Cellular community - eukaryotes hsa04540 Gap junction 1/22 89/9376 4.78855975485189 EGFR 1.74152501868848 Human Diseases Cancer: overview hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer 1/22 90/9376 4.73535353535354 EGFR 1.72677965487591 Organismal Systems Endocrine system hsa04912 GnRH signaling pathway 1/22 93/9376 4.58260019550342 EGFR 1.68381331769818 Human Diseases Cancer: specific types hsa05222 Small cell lung cancer 1/22 93/9376 4.58260019550342 FN1 1.68381331769818 Human Diseases Drug resistance: antineoplastic hsa01522 Endocrine resistance 1/22 99/9376 4.3048668503214 EGFR 1.60312018256095 Human Diseases Cancer: overview hsa05231 Choline metabolism in cancer 1/22 99/9376 4.3048668503214 EGFR 1.60312018256095 Environmental Information Processing Signaling molecules and interaction hsa04061 Viral protein interaction with cytokine and cytokine receptor 1/22 100/9376 4.26181818181818 CSF1R 1.59029493247637 Human Diseases Infectious disease: parasitic hsa05146 Amoebiasis 1/22 103/9376 4.13768755516328 FN1 1.55280340064648 Human Diseases Cancer: specific types hsa05215 Prostate cancer 1/22 106/9376 4.02058319039451 EGFR 1.51670864643124 Human Diseases Endocrine and metabolic disease hsa04931 Insulin resistance 1/22 109/9376 3.90992493744787 CD36 1.48191655472641 Environmental Information Processing Signal transduction hsa04350 TGF-beta signaling pathway 1/22 110/9376 3.87438016528926 FBN1 1.47059368879675 Organismal Systems Immune system hsa04670 Leukocyte transendothelial migration 1/22 116/9376 3.67398119122257 CYBB 1.4053359146864 NA NA hsa04519 Cadherin signaling 2/22 404/9376 2.10981098109811 EGFR/MET 1.10584272088598 Environmental Information Processing Signal transduction hsa04152 AMPK signaling pathway 1/22 122/9376 3.49329359165425 CD36 1.34427116927615 Organismal Systems Endocrine system hsa04926 Relaxin signaling pathway 1/22 130/9376 3.27832167832168 EGFR 1.26855140289414 Environmental Information Processing Signal transduction hsa04068 FoxO signaling pathway 1/22 133/9376 3.20437457279563 EGFR 1.24166097795949 Human Diseases Infectious disease: bacterial hsa05135 Yersinia infection 1/22 138/9376 3.08827404479578 FN1 1.19849534271274 Organismal Systems Endocrine system hsa04915 Estrogen signaling pathway 1/22 139/9376 3.06605624591236 EGFR 1.19009701153335 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 1/22 140/9376 3.04415584415584 MEF2C 1.18177379177577 Organismal Systems Development and regeneration hsa04380 Osteoclast differentiation 1/22 142/9376 3.00128040973111 CSF1R 1.16534757575067 Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 1/22 142/9376 3.00128040973111 MEF2C 1.16534757575067 Human Diseases Cancer: specific types hsa05224 Breast cancer 1/22 148/9376 2.87960687960688 EGFR 1.11774410102597 Environmental Information Processing Signal transduction hsa04072 Phospholipase D signaling pathway 1/22 149/9376 2.86028065893838 EGFR 1.11004258603259 Human Diseases Endocrine and metabolic disease hsa04934 Cushing syndrome 1/22 155/9376 2.74956011730205 EGFR 1.06513340150134 Human Diseases Infectious disease: viral hsa05160 Hepatitis C 1/22 156/9376 2.73193473193473 EGFR 1.05785624942342 Environmental Information Processing Signal transduction hsa04022 cGMP-PKG signaling pathway 1/22 166/9376 2.56736035049288 MEF2C 0.988078344298461 Cellular Processes Cell growth and death hsa04217 Necroptosis 1/22 168/9376 2.53679653679654 CYBB 0.974735210746449 Environmental Information Processing Signal transduction hsa04630 JAK-STAT signaling pathway 1/22 168/9376 2.53679653679654 EGFR 0.974735210746449 Cellular Processes Transport and catabolism hsa04140 Autophagy - animal 1/22 169/9376 2.52178590640129 VMP1 0.968135475328224 Human Diseases Infectious disease: bacterial hsa05152 Tuberculosis 1/22 181/9376 2.35459568056253 MRC1 0.892424332125081 Organismal Systems Immune system hsa04613 Neutrophil extracellular trap formation 1/22 195/9376 2.18554778554779 CYBB 0.811315310029925 Human Diseases Cancer: overview hsa05207 Chemical carcinogenesis - receptor activation 1/22 217/9376 1.96397151235861 EGFR 0.696736131566795 Human Diseases Infectious disease: viral hsa05166 Human T-cell leukemia virus 1 infection 1/22 224/9376 1.9025974025974 NRP1 0.663068472597502 Human Diseases Infectious disease: viral hsa05163 Human cytomegalovirus infection 1/22 227/9376 1.87745294353224 EGFR 0.649005303617364 Human Diseases Infectious disease: bacterial hsa05131 Shigellosis 1/22 253/9376 1.68451311534315 EGFR 0.535268261271876 Human Diseases Neurodegenerative disease hsa05020 Prion disease 1/22 275/9376 1.5497520661157 CYBB 0.448731911883802 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 1/22 298/9376 1.43014032946919 CSF1R 0.365949789836214 NA NA hsa04517 IgSF CAM signaling 1/22 299/9376 1.42535725144421 NRP1 0.362507138620174 Human Diseases Neurodegenerative disease hsa05010 Alzheimer disease 1/22 388/9376 1.09840674789128 CYBB 0.0960080184933835 Human Diseases Neurodegenerative disease hsa05022 Pathways of neurodegeneration - multiple diseases 1/22 480/9376 0.887878787878788 CYBB -0.12229517183