ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0003735 structural constituent of ribosome 81/1416 175/18639 0.462857142857143 6.09265133171913 4.27191260340639e-44 4.84434889226285e-41 GO:0045296 cadherin binding 72/1416 334/18639 0.215568862275449 2.83756216380798 3.40737958553566e-16 1.93198422499872e-13 GO:0009055 electron transfer activity 34/1416 116/18639 0.293103448275862 3.85816043249562 3.16140353963665e-12 1.19501053798265e-09 GO:0003697 single-stranded DNA binding 34/1416 121/18639 0.28099173553719 3.69873231545034 1.17054908973453e-11 3.31850666939738e-09 GO:0140097 catalytic activity, acting on DNA 62/1416 336/18639 0.18452380952381 2.42891192493947 4.89555947598379e-11 1.11031288915312e-08 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 24/1416 68/18639 0.352941176470588 4.64581256231306 6.50093105090481e-11 1.22867596862101e-08 GO:0051082 unfolded protein binding 32/1416 121/18639 0.264462809917355 3.48115982630621 2.62789316468187e-10 4.25718692678462e-08 GO:0008094 ATP-dependent activity, acting on DNA 43/1416 210/18639 0.204761904761905 2.69530871670702 1.74708877254533e-09 2.47649833508301e-07 GO:0003684 damaged DNA binding 23/1416 74/18639 0.310810810810811 4.09124484654146 2.851390531198e-09 3.59275206930948e-07 GO:0044183 protein folding chaperone 23/1416 75/18639 0.306666666666667 4.03669491525424 3.81925958986327e-09 4.33104037490495e-07 GO:0140662 ATP-dependent protein folding chaperone 16/1416 40/18639 0.4 5.26525423728814 1.23499051947775e-08 1.27316295371615e-06 GO:0016887 ATP hydrolysis activity 65/1416 417/18639 0.155875299760192 2.05180770637727 2.11748388098183e-08 2.00102226752783e-06 GO:0042393 histone binding 45/1416 247/18639 0.182186234817814 2.39814211212516 3.24872189639702e-08 2.83388510039556e-06 GO:0019843 rRNA binding 20/1416 65/18639 0.307692307692308 4.05019556714472 3.69767986637162e-08 2.99512069176101e-06 GO:0008137 NADH dehydrogenase (ubiquinone) activity 15/1416 41/18639 0.365853658536585 4.81578131459281 1.44249194089438e-07 1.03426347243588e-05 GO:1990948 ubiquitin ligase inhibitor activity 8/1416 11/18639 0.727272727272727 9.57318952234207 1.45927826798714e-07 1.03426347243588e-05 GO:0022853 active monoatomic ion transmembrane transporter activity 27/1416 118/18639 0.228813559322034 3.0119039069233 1.72697016134466e-07 1.15199068409697e-05 GO:0055105 ubiquitin-protein transferase inhibitor activity 9/1416 15/18639 0.6 7.8978813559322 2.70304890072933e-07 1.70292080745948e-05 GO:0003678 DNA helicase activity 20/1416 74/18639 0.27027027027027 3.55760421438388 3.96612759430108e-07 2.36715194312496e-05 GO:0003954 NADH dehydrogenase activity 15/1416 44/18639 0.340909090909091 4.48743258859784 4.20561940114836e-07 2.38458620045112e-05 GO:0003712 transcription coregulator activity 69/1416 495/18639 0.139393939393939 1.83486132511556 6.40177666928544e-07 3.45695940141414e-05 GO:0004386 helicase activity 30/1416 155/18639 0.193548387096774 2.54770366320394 1.69262201205192e-06 8.72469709848581e-05 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 16/1416 58/18639 0.275862068965517 3.6312098188194 4.2405773239385e-06 0.000200367278556094 GO:0017116 single-stranded DNA helicase activity 16/1416 58/18639 0.275862068965517 3.6312098188194 4.2405773239385e-06 0.000200367278556094 GO:0031491 nucleosome binding 18/1416 74/18639 0.243243243243243 3.20184379294549 7.67014124945278e-06 0.000347917607075178 GO:0003688 DNA replication origin binding 8/1416 16/18639 0.5 6.58156779661017 8.05222416871935e-06 0.00035120085412799 GO:0031625 ubiquitin protein ligase binding 45/1416 302/18639 0.149006622516556 1.96139437647323 1.02708863163792e-05 0.000422561045218329 GO:0070182 DNA polymerase binding 9/1416 21/18639 0.428571428571429 5.64134382566586 1.04336060547736e-05 0.000422561045218329 GO:0003714 transcription corepressor activity 34/1416 204/18639 0.166666666666667 2.19385593220339 1.14549962128653e-05 0.000434141681071052 GO:0044389 ubiquitin-like protein ligase binding 47/1416 322/18639 0.145962732919255 1.92132724497315 1.14852296579644e-05 0.000434141681071052 GO:0042162 telomeric DNA binding 12/1416 38/18639 0.315789473684211 4.15677966101695 1.48505000562362e-05 0.0005432408730249 GO:0000217 DNA secondary structure binding 12/1416 39/18639 0.307692307692308 4.05019556714472 1.99758254342982e-05 0.000707893313827943 GO:0000400 four-way junction DNA binding 8/1416 18/18639 0.444444444444444 5.85028248587571 2.38489200283879e-05 0.000819535615520965 GO:0015078 proton transmembrane transporter activity 31/1416 185/18639 0.167567567567568 2.205714612918 2.46064265519636e-05 0.000820696697350787 GO:0048027 mRNA 5'-UTR binding 9/1416 24/18639 0.375 4.93617584745763 3.76560372964361e-05 0.00122005560840453 GO:0098631 cell adhesion mediator activity 17/1416 76/18639 0.223684210526316 2.94438559322034 4.38006539608607e-05 0.00137972059976711 GO:0140104 molecular carrier activity 37/1416 249/18639 0.14859437751004 1.95596793955483 6.46352577106146e-05 0.00198098330388749 GO:0003689 DNA clamp loader activity 27/1416 160/18639 0.16875 2.22127913135593 7.07937376373479e-05 0.00211263417054612 GO:0005178 integrin binding 27/1416 161/18639 0.167701863354037 2.2074823665649 7.90152016303105e-05 0.00229751893971211 GO:0001618 virus receptor activity 17/1416 81/18639 0.209876543209877 2.76263339610797 0.000102469769171896 0.00290501795602324 GO:0140272 exogenous protein binding 17/1416 82/18639 0.207317073170732 2.72894274493592 0.000120246836672927 0.00332585153139267 GO:0016860 intramolecular oxidoreductase activity 13/1416 53/18639 0.245283018867925 3.22869363607291 0.00012626702077083 0.00340920956081241 GO:0015399 primary active transmembrane transporter activity 27/1416 166/18639 0.162650602409639 2.14099193383704 0.000134406526618761 0.00354458142292267 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 12/1416 48/18639 0.25 3.29078389830508 0.000187769084340693 0.00483932140096241 GO:0031994 insulin-like growth factor I binding 6/1416 13/18639 0.461538461538462 6.07529335071708 0.000204709923432459 0.00515869007049796 GO:0016853 isomerase activity 28/1416 180/18639 0.155555555555556 2.0475988700565 0.000221694302993567 0.00546524651292838 GO:0003713 transcription coactivator activity 36/1416 256/18639 0.140625 1.85106594279661 0.000247269518142985 0.00596603475689671 GO:0055106 ubiquitin-protein transferase regulator activity 10/1416 36/18639 0.277777777777778 3.65642655367232 0.00025270186515246 0.00597008156422686 GO:0016651 oxidoreductase activity, acting on NAD(P)H 17/1416 88/18639 0.193181818181818 2.54287846687211 0.000294932861030064 0.0068255890695529 GO:0008301 DNA binding, bending 7/1416 19/18639 0.368421052631579 4.84957627118644 0.000320884870030659 0.00727766885229534 GO:0140658 ATP-dependent chromatin remodeler activity 25/1416 158/18639 0.158227848101266 2.08277461918043 0.000361191520495611 0.00803119969102005 GO:0030515 snoRNA binding 9/1416 32/18639 0.28125 3.70213188559322 0.000463796300074273 0.0101143270054659 GO:0017069 snRNA binding 12/1416 54/18639 0.222222222222222 2.92514124293785 0.000604808219669955 0.0129406136057685 GO:0140030 modification-dependent protein binding 26/1416 173/18639 0.15028901734104 1.97827471343196 0.000626811833701657 0.0131630485077348 GO:0140713 histone chaperone activity 25/1416 164/18639 0.152439024390244 2.006575547747 0.000638523347544996 0.0131651904748368 GO:0098632 cell-cell adhesion mediator activity 12/1416 55/18639 0.218181818181818 2.87195685670262 0.000720888404327593 0.0145979901876338 GO:0017070 U6 snRNA binding 6/1416 16/18639 0.375 4.93617584745763 0.000783127664675321 0.0155688174497654 GO:0022804 active transmembrane transporter activity 54/1416 457/18639 0.118161925601751 1.55538144865186 0.000796288723180241 0.0155688174497654 GO:0097718 disordered domain specific binding 8/1416 28/18639 0.285714285714286 3.76089588377724 0.000853335536946687 0.016401398286399 GO:0031492 nucleosomal DNA binding 10/1416 42/18639 0.238095238095238 3.1340799031477 0.000962958496947156 0.0181999155923012 GO:0043236 laminin binding 8/1416 29/18639 0.275862068965517 3.6312098188194 0.00110077327906025 0.0204635557123659 GO:1990226 histone methyltransferase binding 6/1416 17/18639 0.352941176470588 4.64581256231306 0.00113295254837823 0.0207220675784018 GO:0051087 protein-folding chaperone binding 21/1416 134/18639 0.156716417910448 2.06287945863901 0.00116857725208492 0.0210343905375285 GO:0043047 single-stranded telomeric DNA binding 5/1416 12/18639 0.416666666666667 5.48463983050847 0.0012650845533039 0.0220512106847679 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 5/1416 12/18639 0.416666666666667 5.48463983050847 0.0012650845533039 0.0220512106847679 GO:0140297 DNA-binding transcription factor binding 56/1416 488/18639 0.114754098360656 1.51052375659906 0.00128340379646797 0.0220512106847679 GO:0050840 extracellular matrix binding 13/1416 67/18639 0.194029850746269 2.55404123450544 0.00140893830314689 0.0238468065040085 GO:0140612 DNA damage sensor activity 7/1416 24/18639 0.291666666666667 3.83924788135593 0.0015743212304534 0.0261479630429334 GO:0070628 proteasome binding 6/1416 18/18639 0.333333333333333 4.38771186440678 0.00159101362430547 0.0261479630429334 GO:0051540 metal cluster binding 14/1416 77/18639 0.181818181818182 2.39329738058552 0.00180738087961425 0.0292795702497508 GO:0140597 protein carrier chaperone 26/1416 188/18639 0.138297872340426 1.8204336458709 0.0021447044309511 0.0333645310744252 GO:0003756 protein disulfide isomerase activity 6/1416 19/18639 0.315789473684211 4.15677966101695 0.00217722689550923 0.0333645310744252 GO:0005520 insulin-like growth factor binding 6/1416 19/18639 0.315789473684211 4.15677966101695 0.00217722689550923 0.0333645310744252 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 6/1416 19/18639 0.315789473684211 4.15677966101695 0.00217722689550923 0.0333645310744252 GO:0000510 H3-H4 histone complex chaperone activity 22/1416 151/18639 0.145695364238411 1.91780783477382 0.00236257155320387 0.0343481556581177 GO:0140584 chromatin extrusion motor activity 22/1416 151/18639 0.145695364238411 1.91780783477382 0.00236257155320387 0.0343481556581177 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 22/1416 151/18639 0.145695364238411 1.91780783477382 0.00236257155320387 0.0343481556581177 GO:0140849 ATP-dependent H2AZ histone chaperone activity 22/1416 151/18639 0.145695364238411 1.91780783477382 0.00236257155320387 0.0343481556581177 GO:1990518 single-stranded 3'-5' DNA helicase activity 10/1416 47/18639 0.212765957446809 2.80066714749369 0.00239556834488347 0.0343870190265551 GO:0015616 DNA translocase activity 22/1416 152/18639 0.144736842105263 1.9051906779661 0.00256914591614769 0.0359680428260677 GO:0140674 ATP-dependent histone chaperone activity 22/1416 152/18639 0.144736842105263 1.9051906779661 0.00256914591614769 0.0359680428260677 GO:0061775 cohesin loader activity 22/1416 153/18639 0.143790849673203 1.89273845131273 0.00279076163746597 0.0381202322362262 GO:0098847 sequence-specific single stranded DNA binding 5/1416 14/18639 0.357142857142857 4.70111985472155 0.00281258305075948 0.0381202322362262 GO:0043138 3'-5' DNA helicase activity 10/1416 48/18639 0.208333333333333 2.74231991525424 0.00282372090638713 0.0381202322362262 GO:0004536 DNA nuclease activity 12/1416 64/18639 0.1875 2.46808792372881 0.00286573738462584 0.0382323081666553 GO:0019838 growth factor binding 20/1416 136/18639 0.147058823529412 1.93575523429711 0.0032620580522701 0.0430136492008639 GO:0015035 protein-disulfide reductase activity 8/1416 34/18639 0.235294117647059 3.09720837487537 0.00331560683766202 0.0431335695212776 GO:0004601 peroxidase activity 11/1416 57/18639 0.192982456140351 2.54025423728814 0.00334722585350303 0.0431335695212776 GO:0004129 cytochrome-c oxidase activity 5/1416 15/18639 0.333333333333333 4.38771186440678 0.00395741349481314 0.0504236730687427 GO:0043021 ribonucleoprotein complex binding 24/1416 177/18639 0.135593220338983 1.78483194484344 0.0040167161108287 0.0506106229964416 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 11/1416 59/18639 0.186440677966102 2.45414392415972 0.00441797162695903 0.0550547233513356 GO:0051536 iron-sulfur cluster binding 13/1416 76/18639 0.171052631578947 2.25158898305085 0.00449601265940721 0.0554182429974758 GO:0032356 oxidized DNA binding 4/1416 10/18639 0.4 5.26525423728814 0.00480029524001475 0.0567034875226742 GO:0047429 nucleoside triphosphate diphosphatase activity 4/1416 10/18639 0.4 5.26525423728814 0.00480029524001475 0.0567034875226742 GO:0097177 mitochondrial ribosome binding 4/1416 10/18639 0.4 5.26525423728814 0.00480029524001475 0.0567034875226742 GO:0098505 G-rich strand telomeric DNA binding 4/1416 10/18639 0.4 5.26525423728814 0.00480029524001475 0.0567034875226742 GO:0000287 magnesium ion binding 29/1416 230/18639 0.126086956521739 1.65969970523213 0.00490398603845545 0.057331135748541 GO:0019205 nucleobase-containing compound kinase activity 9/1416 44/18639 0.204545454545455 2.69245955315871 0.00514029031958956 0.0591557424293922 GO:0016209 antioxidant activity 14/1416 86/18639 0.162790697674419 2.14283602680331 0.00516439021208979 0.0591557424293922 GO:0016675 oxidoreductase activity, acting on a heme group of donors 5/1416 16/18639 0.3125 4.11347987288136 0.00540027069033033 0.0608669985760447 GO:0002039 p53 binding 12/1416 69/18639 0.173913043478261 2.28924097273397 0.00542113479380997 0.0608669985760447 GO:0017134 fibroblast growth factor binding 6/1416 23/18639 0.260869565217391 3.43386145910096 0.00623293237377574 0.0692902350813015 GO:0016835 carbon-oxygen lyase activity 13/1416 79/18639 0.164556962025316 2.16608560394765 0.00629355750738453 0.0692902350813015 GO:0051287 NAD binding 10/1416 54/18639 0.185185185185185 2.43761770244821 0.00683082163034325 0.0737992415689399 GO:0004523 RNA-DNA hybrid ribonuclease activity 4/1416 11/18639 0.363636363636364 4.78659476117103 0.0070935778933108 0.0737992415689399 GO:0015217 ADP transmembrane transporter activity 4/1416 11/18639 0.363636363636364 4.78659476117103 0.0070935778933108 0.0737992415689399 GO:0034511 U3 snoRNA binding 4/1416 11/18639 0.363636363636364 4.78659476117103 0.0070935778933108 0.0737992415689399 GO:0050786 RAGE receptor binding 4/1416 11/18639 0.363636363636364 4.78659476117103 0.0070935778933108 0.0737992415689399 GO:0070990 snRNP binding 4/1416 11/18639 0.363636363636364 4.78659476117103 0.0070935778933108 0.0737992415689399 GO:0061749 forked DNA-dependent helicase activity 9/1416 47/18639 0.191489361702128 2.52060043274432 0.00805314647102145 0.0830206190739847 GO:0043539 protein serine/threonine kinase activator activity 12/1416 73/18639 0.164383561643836 2.1638031112143 0.00855472314220267 0.0873969012906111 GO:0140142 nucleocytoplasmic carrier activity 7/1416 32/18639 0.21875 2.87943591101695 0.00898052009590945 0.0908094056111927 GO:0009378 four-way junction helicase activity 9/1416 48/18639 0.1875 2.46808792372881 0.00925993698593704 0.0908094056111927 GO:0036121 double-stranded DNA helicase activity 9/1416 48/18639 0.1875 2.46808792372881 0.00925993698593704 0.0908094056111927 GO:0035615 clathrin adaptor activity 5/1416 18/18639 0.277777777777778 3.65642655367232 0.00932728387454301 0.0908094056111927 GO:0098641 cadherin binding involved in cell-cell adhesion 5/1416 18/18639 0.277777777777778 3.65642655367232 0.00932728387454301 0.0908094056111927 GO:0015036 disulfide oxidoreductase activity 8/1416 40/18639 0.2 2.63262711864407 0.00936922438845639 0.0908094056111927 GO:0035064 methylated histone binding 12/1416 74/18639 0.162162162162162 2.13456252863033 0.00952406640343286 0.0914704140009422 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 6/1416 25/18639 0.24 3.15915254237288 0.00959874714824702 0.0914704140009422 GO:0005049 nuclear export signal receptor activity 4/1416 12/18639 0.333333333333333 4.38771186440678 0.0100078245633142 0.0937923392958541 GO:0097371 MDM2/MDM4 family protein binding 4/1416 12/18639 0.333333333333333 4.38771186440678 0.0100078245633142 0.0937923392958541 GO:0015631 tubulin binding 42/1416 385/18639 0.109090909090909 1.43597842835131 0.0113508238330541 0.105506837923634 GO:0004529 DNA exonuclease activity 6/1416 26/18639 0.230769230769231 3.03764667535854 0.0116932657460384 0.107150689001544 GO:0140034 methylation-dependent protein binding 12/1416 76/18639 0.157894736842105 2.07838983050847 0.011716653823802 0.107150689001544 GO:0005346 purine ribonucleotide transmembrane transporter activity 5/1416 19/18639 0.263157894736842 3.46398305084746 0.0118808756527694 0.107783303921924 GO:0004520 DNA endonuclease activity 8/1416 42/18639 0.19047619047619 2.50726392251816 0.0125734199068123 0.113160779161311 GO:1990841 promoter-specific chromatin binding 11/1416 68/18639 0.161764705882353 2.12933075772682 0.012980675892893 0.11590619261843 GO:0005542 folic acid binding 4/1416 13/18639 0.307692307692308 4.05019556714472 0.0135989382816879 0.117719053522398 GO:0017154 semaphorin receptor activity 4/1416 13/18639 0.307692307692308 4.05019556714472 0.0135989382816879 0.117719053522398 GO:0019855 calcium channel inhibitor activity 4/1416 13/18639 0.307692307692308 4.05019556714472 0.0135989382816879 0.117719053522398 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 4/1416 13/18639 0.307692307692308 4.05019556714472 0.0135989382816879 0.117719053522398 GO:0004714 transmembrane receptor protein tyrosine kinase activity 10/1416 60/18639 0.166666666666667 2.19385593220339 0.0142637195600667 0.121736367777188 GO:0019199 transmembrane receptor protein kinase activity 12/1416 78/18639 0.153846153846154 2.02509778357236 0.0142777221467072 0.121736367777188 GO:0044325 transmembrane transporter binding 18/1416 136/18639 0.132352941176471 1.7421797108674 0.0147428395889324 0.124764030551114 GO:0140664 ATP-dependent DNA damage sensor activity 5/1416 20/18639 0.25 3.29078389830508 0.0148703151705583 0.12491064743269 GO:0097110 scaffold protein binding 11/1416 70/18639 0.157142857142857 2.06849273607748 0.0159642299634888 0.133113505724973 GO:0019789 SUMO transferase activity 6/1416 28/18639 0.214285714285714 2.82067191283293 0.0168086827885198 0.138123523783924 GO:0051537 2 iron, 2 sulfur cluster binding 6/1416 28/18639 0.214285714285714 2.82067191283293 0.0168086827885198 0.138123523783924 GO:0016829 lyase activity 24/1416 200/18639 0.12 1.57957627118644 0.0173558053319256 0.141593404650386 GO:0140299 molecular sensor activity 11/1416 71/18639 0.154929577464789 2.03935903556935 0.0176355741169492 0.142848150347288 GO:0005347 ATP transmembrane transporter activity 4/1416 14/18639 0.285714285714286 3.76089588377724 0.0179134803740593 0.144070118753072 GO:0140312 cargo adaptor activity 5/1416 21/18639 0.238095238095238 3.1340799031477 0.0183239294370409 0.14633335198313 GO:0003779 actin binding 46/1416 443/18639 0.103837471783296 1.36682672074071 0.0190300525301085 0.150909647336665 GO:0005518 collagen binding 11/1416 72/18639 0.152777777777778 2.01103460451977 0.0194337098653145 0.151905144686065 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 9/1416 54/18639 0.166666666666667 2.19385593220339 0.0195574524904458 0.151905144686065 GO:0140463 chromatin-protein adaptor activity 9/1416 54/18639 0.166666666666667 2.19385593220339 0.0195574524904458 0.151905144686065 GO:0005507 copper ion binding 10/1416 63/18639 0.158730158730159 2.08938660209847 0.0197039935565299 0.152002236007516 GO:0031072 heat shock protein binding 17/1416 131/18639 0.129770992366412 1.70819316858585 0.0208196977013155 0.159523899954674 GO:0043022 ribosome binding 15/1416 112/18639 0.133928571428571 1.76291994552058 0.0222751574971951 0.168964270313497 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 16/1416 122/18639 0.131147540983607 1.72631286468463 0.0223497712054891 0.168964270313497 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 4/1416 15/18639 0.266666666666667 3.51016949152542 0.0229884137846942 0.171505665998969 GO:0061578 K63-linked deubiquitinase activity 4/1416 15/18639 0.266666666666667 3.51016949152542 0.0229884137846942 0.171505665998969 GO:0015215 nucleotide transmembrane transporter activity 6/1416 30/18639 0.2 2.63262711864407 0.0232837399815403 0.172573602216122 GO:0038024 cargo receptor activity 10/1416 65/18639 0.153846153846154 2.02509778357236 0.0240875250937706 0.177371775690492 GO:0000295 adenine nucleotide transmembrane transporter activity 5/1416 23/18639 0.217391304347826 2.86155121591747 0.0267206963813563 0.19159340068567 GO:0003887 DNA-directed DNA polymerase activity 5/1416 23/18639 0.217391304347826 2.86155121591747 0.0267206963813563 0.19159340068567 GO:0004602 glutathione peroxidase activity 5/1416 23/18639 0.217391304347826 2.86155121591747 0.0267206963813563 0.19159340068567 GO:0008171 O-methyltransferase activity 5/1416 23/18639 0.217391304347826 2.86155121591747 0.0267206963813563 0.19159340068567 GO:0031406 carboxylic acid binding 22/1416 187/18639 0.117647058823529 1.54860418743769 0.0269021110604276 0.19159340068567 GO:0016504 peptidase activator activity 9/1416 57/18639 0.157894736842105 2.07838983050847 0.0270325785799887 0.19159340068567 GO:0000062 fatty-acyl-CoA binding 4/1416 16/18639 0.25 3.29078389830508 0.0288511281494821 0.201957897046375 GO:0043023 ribosomal large subunit binding 4/1416 16/18639 0.25 3.29078389830508 0.0288511281494821 0.201957897046375 GO:0043177 organic acid binding 22/1416 189/18639 0.116402116402116 1.53221684153888 0.0298863367732815 0.207015731640815 GO:0008017 microtubule binding 30/1416 276/18639 0.108695652173913 1.43077560795873 0.0300796976196472 0.207015731640815 GO:0016763 pentosyltransferase activity 8/1416 49/18639 0.163265306122449 2.14908336215842 0.0301213366144044 0.207015731640815 GO:0019887 protein kinase regulator activity 28/1416 255/18639 0.109803921568627 1.44536390827517 0.0314202204415306 0.212732784520338 GO:0019902 phosphatase binding 22/1416 190/18639 0.115789473684211 1.52415254237288 0.0314690808388201 0.212732784520338 GO:0050699 WW domain binding 5/1416 24/18639 0.208333333333333 2.74231991525424 0.0317035631251651 0.212732784520338 GO:0070840 dynein complex binding 5/1416 24/18639 0.208333333333333 2.74231991525424 0.0317035631251651 0.212732784520338 GO:0031490 chromatin DNA binding 16/1416 128/18639 0.125 1.64539194915254 0.0332372391767883 0.221711936626341 GO:0030295 protein kinase activator activity 17/1416 139/18639 0.122302158273381 1.60987989269601 0.0346200654981048 0.228331204517956 GO:0001094 TFIID-class transcription factor complex binding 3/1416 10/18639 0.3 3.9489406779661 0.0350349467249774 0.228331204517956 GO:0005345 purine nucleobase transmembrane transporter activity 3/1416 10/18639 0.3 3.9489406779661 0.0350349467249774 0.228331204517956 GO:0008239 dipeptidyl-peptidase activity 3/1416 10/18639 0.3 3.9489406779661 0.0350349467249774 0.228331204517956 GO:0070402 NADPH binding 4/1416 17/18639 0.235294117647059 3.09720837487537 0.035519684528971 0.22885978554462 GO:1901567 fatty acid derivative binding 4/1416 17/18639 0.235294117647059 3.09720837487537 0.035519684528971 0.22885978554462 GO:0033218 amide binding 27/1416 247/18639 0.109311740890688 1.4388852672751 0.0358019698159163 0.229375332040955 GO:0004713 protein tyrosine kinase activity 17/1416 140/18639 0.121428571428571 1.59838075060533 0.0367285494561428 0.233989747658798 GO:0005021 vascular endothelial growth factor receptor activity 8/1416 51/18639 0.156862745098039 2.06480558325025 0.0372521161638814 0.234977273611172 GO:0048487 beta-tubulin binding 7/1416 42/18639 0.166666666666667 2.19385593220339 0.0372979799382813 0.234977273611172 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 9/1416 61/18639 0.147540983606557 1.94210197277021 0.0398504746347257 0.249670929479442 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 6/1416 34/18639 0.176470588235294 2.32290628115653 0.0408023077705445 0.252840530119112 GO:0030332 cyclin binding 6/1416 34/18639 0.176470588235294 2.32290628115653 0.0408023077705445 0.252840530119112 GO:0008200 ion channel inhibitor activity 7/1416 43/18639 0.162790697674419 2.14283602680331 0.0417412894397334 0.257253381655748 GO:0072341 modified amino acid binding 12/1416 91/18639 0.131868131868132 1.73579810020488 0.0423341820713151 0.25841077273845 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 16/1416 132/18639 0.121212121212121 1.59553158705701 0.042384835740169 0.25841077273845 GO:0070064 proline-rich region binding 4/1416 18/18639 0.222222222222222 2.92514124293785 0.0430032275730932 0.260778930844319 GO:0015216 purine nucleotide transmembrane transporter activity 5/1416 26/18639 0.192307692307692 2.53137222946545 0.0433098864940033 0.261241549384041 GO:0002162 dystroglycan binding 3/1416 11/18639 0.272727272727273 3.58994607087827 0.0455129600368523 0.26332498307036 GO:0010854 adenylate cyclase regulator activity 3/1416 11/18639 0.272727272727273 3.58994607087827 0.0455129600368523 0.26332498307036 GO:0015205 nucleobase transmembrane transporter activity 3/1416 11/18639 0.272727272727273 3.58994607087827 0.0455129600368523 0.26332498307036 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 3/1416 11/18639 0.272727272727273 3.58994607087827 0.0455129600368523 0.26332498307036 GO:0032404 mismatch repair complex binding 3/1416 11/18639 0.272727272727273 3.58994607087827 0.0455129600368523 0.26332498307036 GO:0032794 GTPase activating protein binding 3/1416 11/18639 0.272727272727273 3.58994607087827 0.0455129600368523 0.26332498307036 GO:0034056 estrogen response element binding 3/1416 11/18639 0.272727272727273 3.58994607087827 0.0455129600368523 0.26332498307036 GO:0097493 structural molecule activity conferring elasticity 3/1416 11/18639 0.272727272727273 3.58994607087827 0.0455129600368523 0.26332498307036 GO:0140566 histone reader activity 6/1416 35/18639 0.171428571428571 2.25653753026634 0.0462000281373651 0.265488989410834 GO:0016248 channel inhibitor activity 7/1416 44/18639 0.159090909090909 2.09413520801233 0.0465138762460543 0.265488989410834 GO:0051015 actin filament binding 23/1416 209/18639 0.110047846889952 1.44857473035439 0.0465893376479329 0.265488989410834 GO:0120227 acyl-CoA binding 4/1416 19/18639 0.210526315789474 2.77118644067797 0.0513025214185129 0.290885296442968 GO:0141110 transporter inhibitor activity 7/1416 45/18639 0.155555555555556 2.0475988700565 0.0516212958715209 0.291236564767685 GO:0004857 enzyme inhibitor activity 41/1416 416/18639 0.0985576923076923 1.29732826760104 0.0519406364187743 0.291587533162822 GO:0004527 exonuclease activity 11/1416 84/18639 0.130952380952381 1.72374394673123 0.0526581208507036 0.292717201199499 GO:0051117 ATPase binding 11/1416 84/18639 0.130952380952381 1.72374394673123 0.0526581208507036 0.292717201199499 GO:0016922 nuclear receptor binding 16/1416 137/18639 0.116788321167883 1.53730050723741 0.0561824602206643 0.303890831265364 GO:0051020 GTPase binding 32/1416 315/18639 0.101587301587302 1.33720742534302 0.0567151902132268 0.303890831265364 GO:0003725 double-stranded RNA binding 10/1416 75/18639 0.133333333333333 1.75508474576271 0.0567522590785788 0.303890831265364 GO:0019209 kinase activator activity 17/1416 148/18639 0.114864864864865 1.51198179111315 0.0570613865386705 0.303890831265364 GO:0003995 acyl-CoA dehydrogenase activity 3/1416 12/18639 0.25 3.29078389830508 0.0573480051946984 0.303890831265364 GO:0004859 phospholipase inhibitor activity 3/1416 12/18639 0.25 3.29078389830508 0.0573480051946984 0.303890831265364 GO:0005095 GTPase inhibitor activity 3/1416 12/18639 0.25 3.29078389830508 0.0573480051946984 0.303890831265364 GO:0042301 phosphate ion binding 3/1416 12/18639 0.25 3.29078389830508 0.0573480051946984 0.303890831265364 GO:0045295 gamma-catenin binding 3/1416 12/18639 0.25 3.29078389830508 0.0573480051946984 0.303890831265364 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 3/1416 12/18639 0.25 3.29078389830508 0.0573480051946984 0.303890831265364 GO:0042826 histone deacetylase binding 15/1416 127/18639 0.118110236220472 1.55470105431736 0.0581676778356085 0.306800682165489 GO:0061134 peptidase regulator activity 24/1416 226/18639 0.106194690265487 1.39785510724464 0.0600261089129619 0.31513707179305 GO:0008201 heparin binding 19/1416 172/18639 0.11046511627907 1.45406730390225 0.0637831365176314 0.332651378144949 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 5/1416 29/18639 0.172413793103448 2.26950613676213 0.0649238879133554 0.332651378144949 GO:0097472 cyclin-dependent protein kinase activity 5/1416 29/18639 0.172413793103448 2.26950613676213 0.0649238879133554 0.332651378144949 GO:0042887 amide transmembrane transporter activity 6/1416 38/18639 0.157894736842105 2.07838983050847 0.0649416683413871 0.332651378144949 GO:0043531 ADP binding 6/1416 38/18639 0.157894736842105 2.07838983050847 0.0649416683413871 0.332651378144949 GO:0015932 nucleobase-containing compound transmembrane transporter activity 8/1416 57/18639 0.140350877192982 1.84745762711864 0.0651222274675297 0.332651378144949 GO:1901681 sulfur compound binding 28/1416 275/18639 0.101818181818182 1.34024653312789 0.0692760751767378 0.351324737779634 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 3/1416 13/18639 0.230769230769231 3.03764667535854 0.0704727252686016 0.351324737779634 GO:0019104 DNA N-glycosylase activity 3/1416 13/18639 0.230769230769231 3.03764667535854 0.0704727252686016 0.351324737779634 GO:0043560 insulin receptor substrate binding 3/1416 13/18639 0.230769230769231 3.03764667535854 0.0704727252686016 0.351324737779634 GO:0140852 histone ubiquitin ligase activity 3/1416 13/18639 0.230769230769231 3.03764667535854 0.0704727252686016 0.351324737779634 GO:0019207 kinase regulator activity 29/1416 287/18639 0.101045296167247 1.33007293450658 0.0706367197652175 0.351324737779634 GO:0003777 microtubule motor activity 9/1416 68/18639 0.132352941176471 1.7421797108674 0.0710744825792482 0.351958354781081 GO:0016776 phosphotransferase activity, phosphate group as acceptor 6/1416 39/18639 0.153846153846154 2.02509778357236 0.0720454607144993 0.355215445435836 GO:0001968 fibronectin binding 5/1416 30/18639 0.166666666666667 2.19385593220339 0.0732519174997184 0.358050320882244 GO:0035925 mRNA 3'-UTR AU-rich region binding 5/1416 30/18639 0.166666666666667 2.19385593220339 0.0732519174997184 0.358050320882244 GO:0036002 pre-mRNA binding 8/1416 59/18639 0.135593220338983 1.78483194484344 0.0766750502037401 0.371579089448894 GO:0070063 RNA polymerase binding 8/1416 59/18639 0.135593220338983 1.78483194484344 0.0766750502037401 0.371579089448894 GO:0019903 protein phosphatase binding 16/1416 144/18639 0.111111111111111 1.46257062146893 0.0802786267101648 0.381631791533827 GO:0061133 endopeptidase activator activity 4/1416 22/18639 0.181818181818182 2.39329738058552 0.0809903077482771 0.381631791533827 GO:0140517 protein-RNA adaptor activity 4/1416 22/18639 0.181818181818182 2.39329738058552 0.0809903077482771 0.381631791533827 GO:0005310 dicarboxylic acid transmembrane transporter activity 5/1416 31/18639 0.161290322580645 2.12308638600328 0.0821325740571083 0.381631791533827 GO:0072349 modified amino acid transmembrane transporter activity 5/1416 31/18639 0.161290322580645 2.12308638600328 0.0821325740571083 0.381631791533827 GO:0005006 epidermal growth factor receptor activity 7/1416 50/18639 0.14 1.84283898305085 0.0822906612718401 0.381631791533827 GO:0015605 organophosphate ester transmembrane transporter activity 7/1416 50/18639 0.14 1.84283898305085 0.0822906612718401 0.381631791533827 GO:0005200 structural constituent of cytoskeleton 13/1416 112/18639 0.116071428571429 1.5278639527845 0.0824598859327885 0.381631791533827 GO:0001098 basal transcription machinery binding 8/1416 60/18639 0.133333333333333 1.75508474576271 0.082883235873857 0.381631791533827 GO:0001099 basal RNA polymerase II transcription machinery binding 8/1416 60/18639 0.133333333333333 1.75508474576271 0.082883235873857 0.381631791533827 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 8/1416 60/18639 0.133333333333333 1.75508474576271 0.082883235873857 0.381631791533827 GO:0016530 metallochaperone activity 3/1416 14/18639 0.214285714285714 2.82067191283293 0.0848070647852949 0.381631791533827 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 3/1416 14/18639 0.214285714285714 2.82067191283293 0.0848070647852949 0.381631791533827 GO:0030983 mismatched DNA binding 3/1416 14/18639 0.214285714285714 2.82067191283293 0.0848070647852949 0.381631791533827 GO:0044548 S100 protein binding 3/1416 14/18639 0.214285714285714 2.82067191283293 0.0848070647852949 0.381631791533827 GO:0061665 SUMO ligase activity 3/1416 14/18639 0.214285714285714 2.82067191283293 0.0848070647852949 0.381631791533827 GO:1901612 cardiolipin binding 3/1416 14/18639 0.214285714285714 2.82067191283293 0.0848070647852949 0.381631791533827 GO:1990825 sequence-specific mRNA binding 3/1416 14/18639 0.214285714285714 2.82067191283293 0.0848070647852949 0.381631791533827 GO:0016877 ligase activity, forming carbon-sulfur bonds 6/1416 41/18639 0.146341463414634 1.92631252583712 0.0875303366546981 0.390785046324518 GO:0061650 ubiquitin-like protein conjugating enzyme activity 6/1416 41/18639 0.146341463414634 1.92631252583712 0.0875303366546981 0.390785046324518 GO:0003743 translation initiation factor activity 7/1416 51/18639 0.137254901960784 1.80670488534397 0.0894558843571971 0.396261612738522 GO:0005010 insulin-like growth factor receptor activity 7/1416 51/18639 0.137254901960784 1.80670488534397 0.0894558843571971 0.396261612738522 GO:0043425 bHLH transcription factor binding 5/1416 32/18639 0.15625 2.05673993644068 0.0915557217580979 0.4039851691583 GO:0070577 lysine-acetylated histone binding 4/1416 23/18639 0.173913043478261 2.28924097273397 0.0924154890886816 0.406198312506065 GO:0016859 cis-trans isomerase activity 6/1416 42/18639 0.142857142857143 1.88044794188862 0.0959023961074345 0.41989697755147 GO:0035401 histone H3Y41 kinase activity 13/1416 115/18639 0.11304347826087 1.48800663227708 0.0966647308341152 0.419991589141328 GO:0140801 histone H2AXY142 kinase activity 13/1416 115/18639 0.11304347826087 1.48800663227708 0.0966647308341152 0.419991589141328 GO:0008135 translation factor activity, RNA binding 10/1416 83/18639 0.120481927710843 1.5859199509904 0.097586009280786 0.422376085971035 GO:0015556 C4-dicarboxylate transmembrane transporter activity 3/1416 15/18639 0.2 2.63262711864407 0.100261727535445 0.429044524623376 GO:0031386 protein tag activity 3/1416 15/18639 0.2 2.63262711864407 0.100261727535445 0.429044524623376 GO:0141047 molecular tag activity 3/1416 15/18639 0.2 2.63262711864407 0.100261727535445 0.429044524623376 GO:0140416 transcription regulator inhibitor activity 5/1416 33/18639 0.151515151515152 1.99441448382126 0.101508378461257 0.431022905607491 GO:0015294 solute:monoatomic cation symporter activity 13/1416 116/18639 0.112068965517241 1.47517898889538 0.101712099922819 0.431022905607491 GO:0004519 endonuclease activity 14/1416 127/18639 0.110236220472441 1.45105431736287 0.101864319843746 0.431022905607491 GO:0180051 translation factor activity 10/1416 84/18639 0.119047619047619 1.56703995157385 0.103657345555122 0.432164248519101 GO:0030215 semaphorin receptor binding 4/1416 24/18639 0.166666666666667 2.19385593220339 0.104557874281385 0.432164248519101 GO:0050431 transforming growth factor beta binding 4/1416 24/18639 0.166666666666667 2.19385593220339 0.104557874281385 0.432164248519101 GO:0140033 acetylation-dependent protein binding 4/1416 24/18639 0.166666666666667 2.19385593220339 0.104557874281385 0.432164248519101 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 6/1416 43/18639 0.13953488372093 1.83671659440284 0.104685278269764 0.432164248519101 GO:0004864 protein phosphatase inhibitor activity 7/1416 53/18639 0.132075471698113 1.7385273425008 0.104801735751986 0.432164248519101 GO:1901505 carbohydrate derivative transmembrane transporter activity 7/1416 53/18639 0.132075471698113 1.7385273425008 0.104801735751986 0.432164248519101 GO:0016407 acetyltransferase activity 11/1416 96/18639 0.114583333333333 1.50827595338983 0.111455284009886 0.457935840823227 GO:0090482 vitamin transmembrane transporter activity 5/1416 34/18639 0.147058823529412 1.93575523429711 0.111974942373449 0.458410052893468 GO:0004518 nuclease activity 21/1416 209/18639 0.100478468899522 1.32261171032357 0.114973799648155 0.46899384460794 GO:0008296 3'-5'-DNA exonuclease activity 3/1416 16/18639 0.1875 2.46808792372881 0.116741096624513 0.472801441329279 GO:0055102 lipase inhibitor activity 3/1416 16/18639 0.1875 2.46808792372881 0.116741096624513 0.472801441329279 GO:0042974 nuclear retinoic acid receptor binding 4/1416 25/18639 0.16 2.10610169491525 0.117382275645573 0.47370640776541 GO:0003774 cytoskeletal motor activity 16/1416 153/18639 0.104575163398693 1.37653705550017 0.119927831355689 0.482262981409047 GO:0010485 histone H4 acetyltransferase activity 5/1416 35/18639 0.142857142857143 1.88044794188862 0.122937428079462 0.489161555937229 GO:0034061 DNA polymerase activity 5/1416 35/18639 0.142857142857143 1.88044794188862 0.122937428079462 0.489161555937229 GO:0061631 ubiquitin conjugating enzyme activity 5/1416 35/18639 0.142857142857143 1.88044794188862 0.122937428079462 0.489161555937229 GO:0004725 protein tyrosine phosphatase activity 11/1416 98/18639 0.112244897959184 1.47749481148392 0.123912078383322 0.491315723380026 GO:0004197 cysteine-type endopeptidase activity 10/1416 88/18639 0.113636363636364 1.49581086286595 0.130056472193302 0.502911065825111 GO:0019212 phosphatase inhibitor activity 7/1416 56/18639 0.125 1.64539194915254 0.130282451092061 0.502911065825111 GO:0050750 low-density lipoprotein particle receptor binding 4/1416 26/18639 0.153846153846154 2.02509778357236 0.130849982764041 0.502911065825111 GO:0030276 clathrin binding 6/1416 46/18639 0.130434782608696 1.71693072955048 0.13340386041293 0.502911065825111 GO:0004550 nucleoside diphosphate kinase activity 3/1416 17/18639 0.176470588235294 2.32290628115653 0.134145684930701 0.502911065825111 GO:0005092 GDP-dissociation inhibitor activity 3/1416 17/18639 0.176470588235294 2.32290628115653 0.134145684930701 0.502911065825111 GO:0016018 cyclosporin A binding 3/1416 17/18639 0.176470588235294 2.32290628115653 0.134145684930701 0.502911065825111 GO:0017110 nucleoside diphosphate phosphatase activity 3/1416 17/18639 0.176470588235294 2.32290628115653 0.134145684930701 0.502911065825111 GO:0030169 low-density lipoprotein particle binding 3/1416 17/18639 0.176470588235294 2.32290628115653 0.134145684930701 0.502911065825111 GO:0032183 SUMO binding 3/1416 17/18639 0.176470588235294 2.32290628115653 0.134145684930701 0.502911065825111 GO:0051787 misfolded protein binding 3/1416 17/18639 0.176470588235294 2.32290628115653 0.134145684930701 0.502911065825111 GO:0070403 NAD+ binding 3/1416 17/18639 0.176470588235294 2.32290628115653 0.134145684930701 0.502911065825111 GO:0016500 protein-hormone receptor activity 8/1416 67/18639 0.119402985074627 1.57171768277258 0.134251226636944 0.502911065825111 GO:0000993 RNA polymerase II complex binding 5/1416 36/18639 0.138888888888889 1.82821327683616 0.134375708064381 0.502911065825111 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 5/1416 36/18639 0.138888888888889 1.82821327683616 0.134375708064381 0.502911065825111 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 5/1416 36/18639 0.138888888888889 1.82821327683616 0.134375708064381 0.502911065825111 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 5/1416 36/18639 0.138888888888889 1.82821327683616 0.134375708064381 0.502911065825111 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 10/1416 89/18639 0.112359550561798 1.47900399923824 0.137172958469314 0.510013557062958 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 10/1416 89/18639 0.112359550561798 1.47900399923824 0.137172958469314 0.510013557062958 GO:0061733 protein-lysine-acetyltransferase activity 6/1416 47/18639 0.127659574468085 1.68040028849621 0.143727814482276 0.526563922653121 GO:0015370 solute:sodium symporter activity 9/1416 79/18639 0.113924050632911 1.49959772580991 0.144177515340796 0.526563922653121 GO:0140793 histone H2AXY142 phosphatase activity 10/1416 90/18639 0.111111111111111 1.46257062146893 0.1444899723667 0.526563922653121 GO:0004364 glutathione transferase activity 4/1416 27/18639 0.148148148148148 1.95009416195857 0.144919412460825 0.526563922653121 GO:0023026 MHC class II protein complex binding 4/1416 27/18639 0.148148148148148 1.95009416195857 0.144919412460825 0.526563922653121 GO:0035255 ionotropic glutamate receptor binding 4/1416 27/18639 0.148148148148148 1.95009416195857 0.144919412460825 0.526563922653121 GO:0015297 antiporter activity 14/1416 135/18639 0.103703703703704 1.365065913371 0.145492227621782 0.526563922653121 GO:0015291 secondary active transmembrane transporter activity 27/1416 287/18639 0.0940766550522648 1.23834376660958 0.14621444335769 0.526563922653121 GO:0022829 wide pore channel activity 5/1416 37/18639 0.135135135135135 1.77880210719194 0.146267756292534 0.526563922653121 GO:0042805 actinin binding 5/1416 37/18639 0.135135135135135 1.77880210719194 0.146267756292534 0.526563922653121 GO:0008408 3'-5' exonuclease activity 7/1416 58/18639 0.120689655172414 1.58865429573349 0.148827444220894 0.534083296666121 GO:0016779 nucleotidyltransferase activity 14/1416 136/18639 0.102941176470588 1.35502866400798 0.151567327091507 0.534960730774367 GO:0000900 mRNA regulatory element binding translation repressor activity 3/1416 18/18639 0.166666666666667 2.19385593220339 0.152374176402223 0.534960730774367 GO:0008409 5'-3' exonuclease activity 3/1416 18/18639 0.166666666666667 2.19385593220339 0.152374176402223 0.534960730774367 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 3/1416 18/18639 0.166666666666667 2.19385593220339 0.152374176402223 0.534960730774367 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 3/1416 18/18639 0.166666666666667 2.19385593220339 0.152374176402223 0.534960730774367 GO:0031690 adrenergic receptor binding 3/1416 18/18639 0.166666666666667 2.19385593220339 0.152374176402223 0.534960730774367 GO:1901611 phosphatidylglycerol binding 3/1416 18/18639 0.166666666666667 2.19385593220339 0.152374176402223 0.534960730774367 GO:0016879 ligase activity, forming carbon-nitrogen bonds 6/1416 48/18639 0.125 1.64539194915254 0.154404642207101 0.539117227089255 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 32/1416 349/18639 0.0916905444126074 1.20693506871934 0.154508905470906 0.539117227089255 GO:0005539 glycosaminoglycan binding 23/1416 242/18639 0.0950413223140496 1.25104181257879 0.157121360557265 0.540694441184273 GO:0031593 polyubiquitin modification-dependent protein binding 7/1416 59/18639 0.11864406779661 1.56172795173801 0.158540266492435 0.540694441184273 GO:0045499 chemorepellent activity 4/1416 28/18639 0.142857142857143 1.88044794188862 0.159546720898004 0.540694441184273 GO:0051393 alpha-actinin binding 4/1416 28/18639 0.142857142857143 1.88044794188862 0.159546720898004 0.540694441184273 GO:0015101 organic cation transmembrane transporter activity 9/1416 81/18639 0.111111111111111 1.46257062146893 0.160496358923913 0.540694441184273 GO:0001221 transcription coregulator binding 12/1416 115/18639 0.104347826086957 1.37354458364038 0.1632583668734 0.540694441184273 GO:0005004 GPI-linked ephrin receptor activity 6/1416 49/18639 0.122448979591837 1.61181252161882 0.165419038648903 0.540694441184273 GO:0005008 hepatocyte growth factor receptor activity 6/1416 49/18639 0.122448979591837 1.61181252161882 0.165419038648903 0.540694441184273 GO:0005009 insulin receptor activity 6/1416 49/18639 0.122448979591837 1.61181252161882 0.165419038648903 0.540694441184273 GO:0005011 macrophage colony-stimulating factor receptor activity 6/1416 49/18639 0.122448979591837 1.61181252161882 0.165419038648903 0.540694441184273 GO:0005018 platelet-derived growth factor alpha-receptor activity 6/1416 49/18639 0.122448979591837 1.61181252161882 0.165419038648903 0.540694441184273 GO:0005020 stem cell factor receptor activity 6/1416 49/18639 0.122448979591837 1.61181252161882 0.165419038648903 0.540694441184273 GO:0008288 boss receptor activity 6/1416 49/18639 0.122448979591837 1.61181252161882 0.165419038648903 0.540694441184273 GO:0036332 placental growth factor receptor activity 6/1416 49/18639 0.122448979591837 1.61181252161882 0.165419038648903 0.540694441184273 GO:0038062 protein tyrosine kinase collagen receptor activity 6/1416 49/18639 0.122448979591837 1.61181252161882 0.165419038648903 0.540694441184273 GO:0060175 brain-derived neurotrophic factor receptor activity 6/1416 49/18639 0.122448979591837 1.61181252161882 0.165419038648903 0.540694441184273 GO:0019842 vitamin binding 15/1416 150/18639 0.1 1.31631355932203 0.166975690002766 0.540694441184273 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 5/1416 39/18639 0.128205128205128 1.6875814863103 0.171317012906481 0.540694441184273 GO:0008574 plus-end-directed microtubule motor activity 3/1416 19/18639 0.157894736842105 2.07838983050847 0.171325111711668 0.540694441184273 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 3/1416 19/18639 0.157894736842105 2.07838983050847 0.171325111711668 0.540694441184273 GO:0031420 alkali metal ion binding 3/1416 19/18639 0.157894736842105 2.07838983050847 0.171325111711668 0.540694441184273 GO:0070003 threonine-type peptidase activity 3/1416 19/18639 0.157894736842105 2.07838983050847 0.171325111711668 0.540694441184273 GO:0140036 ubiquitin-modified protein reader activity 3/1416 19/18639 0.157894736842105 2.07838983050847 0.171325111711668 0.540694441184273 GO:0008514 organic anion transmembrane transporter activity 25/1416 269/18639 0.0929368029739777 1.22333973914687 0.171871216953042 0.540694441184273 GO:0003680 minor groove of adenine-thymine-rich DNA binding 2/1416 10/18639 0.2 2.63262711864407 0.17307943752195 0.540694441184273 GO:0004955 prostaglandin receptor activity 2/1416 10/18639 0.2 2.63262711864407 0.17307943752195 0.540694441184273 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 2/1416 10/18639 0.2 2.63262711864407 0.17307943752195 0.540694441184273 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 2/1416 10/18639 0.2 2.63262711864407 0.17307943752195 0.540694441184273 GO:0008641 ubiquitin-like modifier activating enzyme activity 2/1416 10/18639 0.2 2.63262711864407 0.17307943752195 0.540694441184273 GO:0016783 sulfurtransferase activity 2/1416 10/18639 0.2 2.63262711864407 0.17307943752195 0.540694441184273 GO:0016868 intramolecular phosphotransferase activity 2/1416 10/18639 0.2 2.63262711864407 0.17307943752195 0.540694441184273 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/1416 10/18639 0.2 2.63262711864407 0.17307943752195 0.540694441184273 GO:0019911 structural constituent of myelin sheath 2/1416 10/18639 0.2 2.63262711864407 0.17307943752195 0.540694441184273 GO:0030957 Tat protein binding 2/1416 10/18639 0.2 2.63262711864407 0.17307943752195 0.540694441184273 GO:0031419 cobalamin binding 2/1416 10/18639 0.2 2.63262711864407 0.17307943752195 0.540694441184273 GO:0035374 chondroitin sulfate binding 2/1416 10/18639 0.2 2.63262711864407 0.17307943752195 0.540694441184273 GO:0042975 peroxisome proliferator activated receptor binding 2/1416 10/18639 0.2 2.63262711864407 0.17307943752195 0.540694441184273 GO:0051880 G-quadruplex DNA binding 2/1416 10/18639 0.2 2.63262711864407 0.17307943752195 0.540694441184273 GO:0106222 lncRNA binding 4/1416 29/18639 0.137931034482759 1.8156049094097 0.174686374175548 0.544215242623822 GO:0005007 fibroblast growth factor receptor activity 6/1416 50/18639 0.12 1.57957627118644 0.176754726473047 0.546157656186473 GO:0005017 platelet-derived growth factor receptor activity 6/1416 50/18639 0.12 1.57957627118644 0.176754726473047 0.546157656186473 GO:0005019 platelet-derived growth factor beta-receptor activity 6/1416 50/18639 0.12 1.57957627118644 0.176754726473047 0.546157656186473 GO:0016836 hydro-lyase activity 7/1416 61/18639 0.114754098360656 1.51052375659906 0.178793402692377 0.55095575720966 GO:0004867 serine-type endopeptidase inhibitor activity 10/1416 95/18639 0.105263157894737 1.38559322033898 0.183937919257278 0.565231083137228 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 5/1416 40/18639 0.125 1.64539194915254 0.18442284017705 0.565231083137228 GO:0005030 neurotrophin receptor activity 6/1416 51/18639 0.117647058823529 1.54860418743769 0.188394572088494 0.566697992661067 GO:0016597 amino acid binding 6/1416 51/18639 0.117647058823529 1.54860418743769 0.188394572088494 0.566697992661067 GO:0004521 RNA endonuclease activity 8/1416 73/18639 0.10958904109589 1.4425354074762 0.18846098128758 0.566697992661067 GO:0019888 protein phosphatase regulator activity 11/1416 107/18639 0.102803738317757 1.35321954696658 0.188786931165422 0.566697992661067 GO:0008106 alcohol dehydrogenase (NADP+) activity 4/1416 30/18639 0.133333333333333 1.75508474576271 0.190291675202599 0.566697992661067 GO:0016769 transferase activity, transferring nitrogenous groups 4/1416 30/18639 0.133333333333333 1.75508474576271 0.190291675202599 0.566697992661067 GO:0000339 RNA cap binding 3/1416 20/18639 0.15 1.97447033898305 0.190898265605404 0.566697992661067 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 3/1416 20/18639 0.15 1.97447033898305 0.190898265605404 0.566697992661067 GO:0010851 cyclase regulator activity 3/1416 20/18639 0.15 1.97447033898305 0.190898265605404 0.566697992661067 GO:0042288 MHC class I protein binding 3/1416 20/18639 0.15 1.97447033898305 0.190898265605404 0.566697992661067 GO:0043024 ribosomal small subunit binding 3/1416 20/18639 0.15 1.97447033898305 0.190898265605404 0.566697992661067 GO:0061608 nuclear import signal receptor activity 3/1416 20/18639 0.15 1.97447033898305 0.190898265605404 0.566697992661067 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 5/1416 41/18639 0.121951219512195 1.6052604381976 0.197880132332932 0.573916669538029 GO:1901682 sulfur compound transmembrane transporter activity 7/1416 63/18639 0.111111111111111 1.46257062146893 0.200070994434122 0.573916669538029 GO:0032182 ubiquitin-like protein binding 12/1416 120/18639 0.1 1.31631355932203 0.200222578055417 0.573916669538029 GO:0005080 protein kinase C binding 6/1416 52/18639 0.115384615384615 1.51882333767927 0.200320700992473 0.573916669538029 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 2/1416 11/18639 0.181818181818182 2.39329738058552 0.201427543629749 0.573916669538029 GO:0004954 prostanoid receptor activity 2/1416 11/18639 0.181818181818182 2.39329738058552 0.201427543629749 0.573916669538029 GO:0008271 secondary active sulfate transmembrane transporter activity 2/1416 11/18639 0.181818181818182 2.39329738058552 0.201427543629749 0.573916669538029 GO:0008432 JUN kinase binding 2/1416 11/18639 0.181818181818182 2.39329738058552 0.201427543629749 0.573916669538029 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 2/1416 11/18639 0.181818181818182 2.39329738058552 0.201427543629749 0.573916669538029 GO:0019206 nucleoside kinase activity 2/1416 11/18639 0.181818181818182 2.39329738058552 0.201427543629749 0.573916669538029 GO:0032050 clathrin heavy chain binding 2/1416 11/18639 0.181818181818182 2.39329738058552 0.201427543629749 0.573916669538029 GO:0043522 leucine zipper domain binding 2/1416 11/18639 0.181818181818182 2.39329738058552 0.201427543629749 0.573916669538029 GO:0045294 alpha-catenin binding 2/1416 11/18639 0.181818181818182 2.39329738058552 0.201427543629749 0.573916669538029 GO:0047676 arachidonate-CoA ligase activity 2/1416 11/18639 0.181818181818182 2.39329738058552 0.201427543629749 0.573916669538029 GO:0048407 platelet-derived growth factor binding 2/1416 11/18639 0.181818181818182 2.39329738058552 0.201427543629749 0.573916669538029 GO:0050998 nitric-oxide synthase binding 2/1416 11/18639 0.181818181818182 2.39329738058552 0.201427543629749 0.573916669538029 GO:0008327 methyl-CpG binding 4/1416 31/18639 0.129032258064516 1.69846910880262 0.206315245742671 0.583445108908203 GO:0016878 acid-thiol ligase activity 4/1416 31/18639 0.129032258064516 1.69846910880262 0.206315245742671 0.583445108908203 GO:0070325 lipoprotein particle receptor binding 4/1416 31/18639 0.129032258064516 1.69846910880262 0.206315245742671 0.583445108908203 GO:0001846 opsonin binding 3/1416 21/18639 0.142857142857143 1.88044794188862 0.210995757766673 0.58493099364765 GO:0010314 phosphatidylinositol-5-phosphate binding 3/1416 21/18639 0.142857142857143 1.88044794188862 0.210995757766673 0.58493099364765 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 3/1416 21/18639 0.142857142857143 1.88044794188862 0.210995757766673 0.58493099364765 GO:0072542 protein phosphatase activator activity 3/1416 21/18639 0.142857142857143 1.88044794188862 0.210995757766673 0.58493099364765 GO:0004402 histone acetyltransferase activity 5/1416 42/18639 0.119047619047619 1.56703995157385 0.211660907498539 0.58493099364765 GO:0008307 structural constituent of muscle 5/1416 42/18639 0.119047619047619 1.56703995157385 0.211660907498539 0.58493099364765 GO:0043175 RNA polymerase core enzyme binding 5/1416 42/18639 0.119047619047619 1.56703995157385 0.211660907498539 0.58493099364765 GO:0005003 ephrin receptor activity 6/1416 53/18639 0.113207547169811 1.49016629357211 0.212514611448705 0.58493099364765 GO:0005005 transmembrane-ephrin receptor activity 6/1416 53/18639 0.113207547169811 1.49016629357211 0.212514611448705 0.58493099364765 GO:0034212 protein N-acetyltransferase activity 6/1416 53/18639 0.113207547169811 1.49016629357211 0.212514611448705 0.58493099364765 GO:0038064 collagen receptor activity 6/1416 53/18639 0.113207547169811 1.49016629357211 0.212514611448705 0.58493099364765 GO:0015293 symporter activity 14/1416 146/18639 0.0958904109589041 1.26221848154168 0.219254692368706 0.598056964129399 GO:0051059 NF-kappaB binding 4/1416 32/18639 0.125 1.64539194915254 0.222709463454753 0.598056964129399 GO:0071813 lipoprotein particle binding 4/1416 32/18639 0.125 1.64539194915254 0.222709463454753 0.598056964129399 GO:0071814 protein-lipid complex binding 4/1416 32/18639 0.125 1.64539194915254 0.222709463454753 0.598056964129399 GO:0003925 G protein activity 6/1416 54/18639 0.111111111111111 1.46257062146893 0.224957285726164 0.598056964129399 GO:0050661 NADP binding 6/1416 54/18639 0.111111111111111 1.46257062146893 0.224957285726164 0.598056964129399 GO:0000340 RNA 7-methylguanosine cap binding 2/1416 12/18639 0.166666666666667 2.19385593220339 0.230243451316759 0.598056964129399 GO:0004032 aldose reductase (NADPH) activity 2/1416 12/18639 0.166666666666667 2.19385593220339 0.230243451316759 0.598056964129399 GO:0004300 enoyl-CoA hydratase activity 2/1416 12/18639 0.166666666666667 2.19385593220339 0.230243451316759 0.598056964129399 GO:0005436 sodium:phosphate symporter activity 2/1416 12/18639 0.166666666666667 2.19385593220339 0.230243451316759 0.598056964129399 GO:0010853 cyclase activator activity 2/1416 12/18639 0.166666666666667 2.19385593220339 0.230243451316759 0.598056964129399 GO:0016801 hydrolase activity, acting on ether bonds 2/1416 12/18639 0.166666666666667 2.19385593220339 0.230243451316759 0.598056964129399 GO:0016803 ether hydrolase activity 2/1416 12/18639 0.166666666666667 2.19385593220339 0.230243451316759 0.598056964129399 GO:0017166 vinculin binding 2/1416 12/18639 0.166666666666667 2.19385593220339 0.230243451316759 0.598056964129399 GO:0031543 peptidyl-proline dioxygenase activity 2/1416 12/18639 0.166666666666667 2.19385593220339 0.230243451316759 0.598056964129399 GO:0035197 siRNA binding 2/1416 12/18639 0.166666666666667 2.19385593220339 0.230243451316759 0.598056964129399 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 2/1416 12/18639 0.166666666666667 2.19385593220339 0.230243451316759 0.598056964129399 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 2/1416 12/18639 0.166666666666667 2.19385593220339 0.230243451316759 0.598056964129399 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 2/1416 12/18639 0.166666666666667 2.19385593220339 0.230243451316759 0.598056964129399 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 2/1416 12/18639 0.166666666666667 2.19385593220339 0.230243451316759 0.598056964129399 GO:1990247 N6-methyladenosine-containing RNA reader activity 2/1416 12/18639 0.166666666666667 2.19385593220339 0.230243451316759 0.598056964129399 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 3/1416 22/18639 0.136363636363636 1.79497303543914 0.231522934085367 0.598056964129399 GO:0031683 G-protein beta/gamma-subunit complex binding 3/1416 22/18639 0.136363636363636 1.79497303543914 0.231522934085367 0.598056964129399 GO:0034062 5'-3' RNA polymerase activity 3/1416 22/18639 0.136363636363636 1.79497303543914 0.231522934085367 0.598056964129399 GO:0070034 telomerase RNA binding 3/1416 22/18639 0.136363636363636 1.79497303543914 0.231522934085367 0.598056964129399 GO:0097747 RNA polymerase activity 3/1416 22/18639 0.136363636363636 1.79497303543914 0.231522934085367 0.598056964129399 GO:0140035 ubiquitin-like protein reader activity 3/1416 22/18639 0.136363636363636 1.79497303543914 0.231522934085367 0.598056964129399 GO:0061135 endopeptidase regulator activity 17/1416 184/18639 0.0923913043478261 1.21615926676492 0.234253262490768 0.603734544692117 GO:0005158 insulin receptor binding 3/1416 23/18639 0.130434782608696 1.71693072955048 0.25238905083487 0.647532089698513 GO:0140103 catalytic activity, acting on a glycoprotein 3/1416 23/18639 0.130434782608696 1.71693072955048 0.25238905083487 0.647532089698513 GO:0004715 non-membrane spanning protein tyrosine kinase activity 5/1416 45/18639 0.111111111111111 1.46257062146893 0.254657433248508 0.647660556348114 GO:0051539 4 iron, 4 sulfur cluster binding 5/1416 45/18639 0.111111111111111 1.46257062146893 0.254657433248508 0.647660556348114 GO:0004721 phosphoprotein phosphatase activity 16/1416 175/18639 0.0914285714285714 1.20348668280872 0.255867459405328 0.647660556348114 GO:0008376 acetylgalactosaminyltransferase activity 4/1416 34/18639 0.117647058823529 1.54860418743769 0.256420442770324 0.647660556348114 GO:0016831 carboxy-lyase activity 4/1416 34/18639 0.117647058823529 1.54860418743769 0.256420442770324 0.647660556348114 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 2/1416 13/18639 0.153846153846154 2.02509778357236 0.259292674234606 0.647660556348114 GO:0035673 oligopeptide transmembrane transporter activity 2/1416 13/18639 0.153846153846154 2.02509778357236 0.259292674234606 0.647660556348114 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 2/1416 13/18639 0.153846153846154 2.02509778357236 0.259292674234606 0.647660556348114 GO:0061459 L-arginine transmembrane transporter activity 2/1416 13/18639 0.153846153846154 2.02509778357236 0.259292674234606 0.647660556348114 GO:0097157 pre-mRNA intronic binding 2/1416 13/18639 0.153846153846154 2.02509778357236 0.259292674234606 0.647660556348114 GO:0140666 annealing activity 2/1416 13/18639 0.153846153846154 2.02509778357236 0.259292674234606 0.647660556348114 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 2/1416 13/18639 0.153846153846154 2.02509778357236 0.259292674234606 0.647660556348114 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 12/1416 128/18639 0.09375 1.23404396186441 0.266076143140476 0.663143618288571 GO:0008080 N-acetyltransferase activity 7/1416 69/18639 0.101449275362319 1.33539056742815 0.268990961212537 0.668599586883377 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 5/1416 46/18639 0.108695652173913 1.43077560795873 0.269444454326017 0.668599586883377 GO:0001091 RNA polymerase II general transcription initiation factor binding 3/1416 24/18639 0.125 1.64539194915254 0.273507790342511 0.67167177766972 GO:0005315 phosphate transmembrane transporter activity 3/1416 24/18639 0.125 1.64539194915254 0.273507790342511 0.67167177766972 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 3/1416 24/18639 0.125 1.64539194915254 0.273507790342511 0.67167177766972 GO:0035035 histone acetyltransferase binding 3/1416 24/18639 0.125 1.64539194915254 0.273507790342511 0.67167177766972 GO:0005343 organic acid:sodium symporter activity 4/1416 35/18639 0.114285714285714 1.5043583535109 0.273644057569145 0.67167177766972 GO:0019208 phosphatase regulator activity 11/1416 117/18639 0.094017094017094 1.23755975662755 0.275119059583477 0.673833722608343 GO:0005504 fatty acid binding 5/1416 47/18639 0.106382978723404 1.40033357374684 0.284410720974082 0.69034921611743 GO:0016410 N-acyltransferase activity 9/1416 94/18639 0.0957446808510638 1.26030021637216 0.284496628569935 0.69034921611743 GO:0008013 beta-catenin binding 10/1416 106/18639 0.0943396226415094 1.24180524464343 0.284739098495216 0.69034921611743 GO:0005525 GTP binding 32/1416 378/18639 0.0846560846560847 1.11433952111918 0.286209644758845 0.69034921611743 GO:0004705 JUN kinase activity 2/1416 14/18639 0.142857142857143 1.88044794188862 0.288373609142825 0.69034921611743 GO:0015926 glucosidase activity 2/1416 14/18639 0.142857142857143 1.88044794188862 0.288373609142825 0.69034921611743 GO:0019992 diacylglycerol binding 2/1416 14/18639 0.142857142857143 1.88044794188862 0.288373609142825 0.69034921611743 GO:0071933 Arp2/3 complex binding 2/1416 14/18639 0.142857142857143 1.88044794188862 0.288373609142825 0.69034921611743 GO:0001786 phosphatidylserine binding 6/1416 59/18639 0.101694915254237 1.33862395863258 0.290213669439741 0.69034921611743 GO:0004879 nuclear receptor activity 6/1416 59/18639 0.101694915254237 1.33862395863258 0.290213669439741 0.69034921611743 GO:0004033 aldo-keto reductase (NADPH) activity 4/1416 36/18639 0.111111111111111 1.46257062146893 0.291052601257241 0.69034921611743 GO:0044390 ubiquitin-like protein conjugating enzyme binding 4/1416 36/18639 0.111111111111111 1.46257062146893 0.291052601257241 0.69034921611743 GO:0001848 complement binding 3/1416 25/18639 0.12 1.57957627118644 0.29479763325573 0.69034921611743 GO:0003707 nuclear steroid receptor activity 3/1416 25/18639 0.12 1.57957627118644 0.29479763325573 0.69034921611743 GO:0008483 transaminase activity 3/1416 25/18639 0.12 1.57957627118644 0.29479763325573 0.69034921611743 GO:0015645 fatty acid ligase activity 3/1416 25/18639 0.12 1.57957627118644 0.29479763325573 0.69034921611743 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 3/1416 25/18639 0.12 1.57957627118644 0.29479763325573 0.69034921611743 GO:0017056 structural constituent of nuclear pore 3/1416 25/18639 0.12 1.57957627118644 0.29479763325573 0.69034921611743 GO:0019211 phosphatase activator activity 3/1416 25/18639 0.12 1.57957627118644 0.29479763325573 0.69034921611743 GO:0120515 fatty acid-CoA ligase activity 3/1416 25/18639 0.12 1.57957627118644 0.29479763325573 0.69034921611743 GO:0016757 glycosyltransferase activity 23/1416 267/18639 0.0861423220973783 1.13390306608265 0.294974974213622 0.69034921611743 GO:0005201 extracellular matrix structural constituent 15/1416 168/18639 0.0892857142857143 1.17527996368039 0.295255176205426 0.69034921611743 GO:0032266 phosphatidylinositol-3-phosphate binding 5/1416 48/18639 0.104166666666667 1.37115995762712 0.299527706877218 0.69889798271351 GO:0030414 peptidase inhibitor activity 15/1416 169/18639 0.0887573964497041 1.16832564436867 0.303178320759267 0.705807587555824 GO:0098531 ligand-modulated transcription factor activity 6/1416 60/18639 0.1 1.31631355932203 0.303733776655416 0.705807587555824 GO:0023023 MHC protein complex binding 4/1416 37/18639 0.108108108108108 1.42304168575355 0.308602279434781 0.707053757972596 GO:0004540 RNA nuclease activity 11/1416 121/18639 0.0909090909090909 1.19664869029276 0.312687926303315 0.707053757972596 GO:0035254 glutamate receptor binding 5/1416 49/18639 0.102040816326531 1.34317710134901 0.3147673282668 0.707053757972596 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 3/1416 26/18639 0.115384615384615 1.51882333767927 0.31618210940682 0.707053757972596 GO:0034237 protein kinase A regulatory subunit binding 3/1416 26/18639 0.115384615384615 1.51882333767927 0.31618210940682 0.707053757972596 GO:0043548 phosphatidylinositol 3-kinase binding 3/1416 26/18639 0.115384615384615 1.51882333767927 0.31618210940682 0.707053757972596 GO:0050681 nuclear androgen receptor binding 3/1416 26/18639 0.115384615384615 1.51882333767927 0.31618210940682 0.707053757972596 GO:0031267 small GTPase binding 24/1416 283/18639 0.0848056537102474 1.11630831885968 0.31676010568236 0.707053757972596 GO:0000774 adenyl-nucleotide exchange factor activity 2/1416 15/18639 0.133333333333333 1.75508474576271 0.317313898620883 0.707053757972596 GO:0004467 long-chain fatty acid-CoA ligase activity 2/1416 15/18639 0.133333333333333 1.75508474576271 0.317313898620883 0.707053757972596 GO:0004953 icosanoid receptor activity 2/1416 15/18639 0.133333333333333 1.75508474576271 0.317313898620883 0.707053757972596 GO:0005041 low-density lipoprotein particle receptor activity 2/1416 15/18639 0.133333333333333 1.75508474576271 0.317313898620883 0.707053757972596 GO:0015116 sulfate transmembrane transporter activity 2/1416 15/18639 0.133333333333333 1.75508474576271 0.317313898620883 0.707053757972596 GO:0033130 acetylcholine receptor binding 2/1416 15/18639 0.133333333333333 1.75508474576271 0.317313898620883 0.707053757972596 GO:0048531 beta-1,3-galactosyltransferase activity 2/1416 15/18639 0.133333333333333 1.75508474576271 0.317313898620883 0.707053757972596 GO:0050780 dopamine receptor binding 2/1416 15/18639 0.133333333333333 1.75508474576271 0.317313898620883 0.707053757972596 GO:0051371 muscle alpha-actinin binding 2/1416 15/18639 0.133333333333333 1.75508474576271 0.317313898620883 0.707053757972596 GO:0120283 protein serine/threonine kinase binding 2/1416 15/18639 0.133333333333333 1.75508474576271 0.317313898620883 0.707053757972596 GO:0140161 monocarboxylate:sodium symporter activity 2/1416 15/18639 0.133333333333333 1.75508474576271 0.317313898620883 0.707053757972596 GO:0140776 protein-containing complex destabilizing activity 2/1416 15/18639 0.133333333333333 1.75508474576271 0.317313898620883 0.707053757972596 GO:0015026 coreceptor activity 6/1416 61/18639 0.0983606557377049 1.29473464851348 0.317363635633202 0.707053757972596 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 8/1416 86/18639 0.0930232558139535 1.22447772960189 0.329103599918043 0.731771533935414 GO:0048029 monosaccharide binding 7/1416 74/18639 0.0945945945945946 1.24516147503436 0.330536855712292 0.733520145553305 GO:0019001 guanyl nucleotide binding 33/1416 400/18639 0.0825 1.08595868644068 0.335632364410344 0.737456306314838 GO:0032561 guanyl ribonucleotide binding 33/1416 400/18639 0.0825 1.08595868644068 0.335632364410344 0.737456306314838 GO:0005044 scavenger receptor activity 3/1416 27/18639 0.111111111111111 1.46257062146893 0.337589946525069 0.737456306314838 GO:0005385 zinc ion transmembrane transporter activity 3/1416 27/18639 0.111111111111111 1.46257062146893 0.337589946525069 0.737456306314838 GO:0016405 CoA-ligase activity 3/1416 27/18639 0.111111111111111 1.46257062146893 0.337589946525069 0.737456306314838 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 3/1416 27/18639 0.111111111111111 1.46257062146893 0.337589946525069 0.737456306314838 GO:0002020 protease binding 12/1416 136/18639 0.0882352941176471 1.16145314057827 0.33798689478963 0.737456306314838 GO:0140789 histone phosphatase activity 12/1416 136/18639 0.0882352941176471 1.16145314057827 0.33798689478963 0.737456306314838 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 4/1416 39/18639 0.102564102564103 1.35006518904824 0.343957513779406 0.737456306314838 GO:0016830 carbon-carbon lyase activity 5/1416 51/18639 0.0980392156862745 1.29050348953141 0.345505049811498 0.737456306314838 GO:0030544 Hsp70 protein binding 5/1416 51/18639 0.0980392156862745 1.29050348953141 0.345505049811498 0.737456306314838 GO:0004707 MAP kinase activity 2/1416 16/18639 0.125 1.64539194915254 0.345967156048936 0.737456306314838 GO:0004708 MAP kinase kinase activity 2/1416 16/18639 0.125 1.64539194915254 0.345967156048936 0.737456306314838 GO:0005024 transforming growth factor beta receptor activity 2/1416 16/18639 0.125 1.64539194915254 0.345967156048936 0.737456306314838 GO:0005159 insulin-like growth factor receptor binding 2/1416 16/18639 0.125 1.64539194915254 0.345967156048936 0.737456306314838 GO:0005324 long-chain fatty acid transmembrane transporter activity 2/1416 16/18639 0.125 1.64539194915254 0.345967156048936 0.737456306314838 GO:0008142 oxysterol binding 2/1416 16/18639 0.125 1.64539194915254 0.345967156048936 0.737456306314838 GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity 2/1416 16/18639 0.125 1.64539194915254 0.345967156048936 0.737456306314838 GO:0022858 alanine transmembrane transporter activity 2/1416 16/18639 0.125 1.64539194915254 0.345967156048936 0.737456306314838 GO:0030275 LRR domain binding 2/1416 16/18639 0.125 1.64539194915254 0.345967156048936 0.737456306314838 GO:0034450 ubiquitin-ubiquitin ligase activity 2/1416 16/18639 0.125 1.64539194915254 0.345967156048936 0.737456306314838 GO:0043130 ubiquitin binding 9/1416 100/18639 0.09 1.18468220338983 0.348886405827366 0.742283647670231 GO:0046943 carboxylic acid transmembrane transporter activity 16/1416 188/18639 0.0851063829787234 1.12026685899748 0.355436465778214 0.754803281259354 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 3/1416 28/18639 0.107142857142857 1.41033595641646 0.358955133600317 0.75813158872411 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 5/1416 52/18639 0.0961538461538462 1.26568611473272 0.360950193302885 0.75813158872411 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 4/1416 40/18639 0.1 1.31631355932203 0.361683588624112 0.75813158872411 GO:0030331 nuclear estrogen receptor binding 4/1416 40/18639 0.1 1.31631355932203 0.361683588624112 0.75813158872411 GO:0061791 GTPase motor activity 4/1416 40/18639 0.1 1.31631355932203 0.361683588624112 0.75813158872411 GO:0071949 FAD binding 4/1416 40/18639 0.1 1.31631355932203 0.361683588624112 0.75813158872411 GO:1990606 membrane scission GTPase motor activity 4/1416 40/18639 0.1 1.31631355932203 0.361683588624112 0.75813158872411 GO:0005342 organic acid transmembrane transporter activity 16/1416 189/18639 0.0846560846560847 1.11433952111918 0.363430725862559 0.760388271454136 GO:0003727 single-stranded RNA binding 8/1416 89/18639 0.0898876404494382 1.18320319939059 0.364145513143459 0.760480684907335 GO:0004029 aldehyde dehydrogenase (NAD+) activity 2/1416 17/18639 0.117647058823529 1.54860418743769 0.374210018864701 0.76719925257561 GO:0004549 tRNA-specific ribonuclease activity 2/1416 17/18639 0.117647058823529 1.54860418743769 0.374210018864701 0.76719925257561 GO:0004659 prenyltransferase activity 2/1416 17/18639 0.117647058823529 1.54860418743769 0.374210018864701 0.76719925257561 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 2/1416 17/18639 0.117647058823529 1.54860418743769 0.374210018864701 0.76719925257561 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/1416 17/18639 0.117647058823529 1.54860418743769 0.374210018864701 0.76719925257561 GO:0019198 transmembrane receptor protein phosphatase activity 2/1416 17/18639 0.117647058823529 1.54860418743769 0.374210018864701 0.76719925257561 GO:0046965 nuclear retinoid X receptor binding 2/1416 17/18639 0.117647058823529 1.54860418743769 0.374210018864701 0.76719925257561 GO:0048038 quinone binding 2/1416 17/18639 0.117647058823529 1.54860418743769 0.374210018864701 0.76719925257561 GO:0005246 calcium channel regulator activity 5/1416 53/18639 0.0943396226415094 1.24180524464343 0.376412233079362 0.76719925257561 GO:0017046 peptide hormone binding 5/1416 53/18639 0.0943396226415094 1.24180524464343 0.376412233079362 0.76719925257561 GO:0051018 protein kinase A binding 5/1416 53/18639 0.0943396226415094 1.24180524464343 0.376412233079362 0.76719925257561 GO:0140296 general transcription initiation factor binding 5/1416 53/18639 0.0943396226415094 1.24180524464343 0.376412233079362 0.76719925257561 GO:0015175 neutral L-amino acid transmembrane transporter activity 4/1416 41/18639 0.0975609756097561 1.28420835055808 0.379392070385321 0.76719925257561 GO:0017080 sodium channel regulator activity 4/1416 41/18639 0.0975609756097561 1.28420835055808 0.379392070385321 0.76719925257561 GO:0140318 protein transporter activity 4/1416 41/18639 0.0975609756097561 1.28420835055808 0.379392070385321 0.76719925257561 GO:0003785 actin monomer binding 3/1416 29/18639 0.103448275862069 1.36170368205728 0.380216913533944 0.76719925257561 GO:0010484 histone H3 acetyltransferase activity 3/1416 29/18639 0.103448275862069 1.36170368205728 0.380216913533944 0.76719925257561 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 3/1416 29/18639 0.103448275862069 1.36170368205728 0.380216913533944 0.76719925257561 GO:0051861 glycolipid binding 3/1416 29/18639 0.103448275862069 1.36170368205728 0.380216913533944 0.76719925257561 GO:0016874 ligase activity 14/1416 167/18639 0.0838323353293413 1.10349639703644 0.390941840113766 0.787438804065738 GO:0035198 miRNA binding 4/1416 42/18639 0.0952380952380952 1.25363196125908 0.39704798226814 0.79131838899588 GO:0035173 histone kinase activity 29/1416 360/18639 0.0805555555555556 1.06036370056497 0.398614377417195 0.79131838899588 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 6/1416 67/18639 0.0895522388059701 1.17878826207943 0.400372845423993 0.79131838899588 GO:0043995 histone H4K5 acetyltransferase activity 3/1416 30/18639 0.1 1.31631355932203 0.401319717792983 0.79131838899588 GO:0043996 histone H4K8 acetyltransferase activity 3/1416 30/18639 0.1 1.31631355932203 0.401319717792983 0.79131838899588 GO:0043997 histone H4K12 acetyltransferase activity 3/1416 30/18639 0.1 1.31631355932203 0.401319717792983 0.79131838899588 GO:0003746 translation elongation factor activity 2/1416 18/18639 0.111111111111111 1.46257062146893 0.40193949917251 0.79131838899588 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 2/1416 18/18639 0.111111111111111 1.46257062146893 0.40193949917251 0.79131838899588 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/1416 18/18639 0.111111111111111 1.46257062146893 0.40193949917251 0.79131838899588 GO:0008308 voltage-gated monoatomic anion channel activity 2/1416 18/18639 0.111111111111111 1.46257062146893 0.40193949917251 0.79131838899588 GO:0030228 lipoprotein particle receptor activity 2/1416 18/18639 0.111111111111111 1.46257062146893 0.40193949917251 0.79131838899588 GO:0034185 apolipoprotein binding 2/1416 18/18639 0.111111111111111 1.46257062146893 0.40193949917251 0.79131838899588 GO:1990381 ubiquitin-specific protease binding 2/1416 18/18639 0.111111111111111 1.46257062146893 0.40193949917251 0.79131838899588 GO:0005516 calmodulin binding 17/1416 207/18639 0.0821256038647343 1.0810304593466 0.405498269896226 0.796941140489291 GO:0048306 calcium-dependent protein binding 7/1416 80/18639 0.0875 1.15177436440678 0.406575945749336 0.797676682490913 GO:0004712 protein serine/threonine/tyrosine kinase activity 4/1416 43/18639 0.0930232558139535 1.22447772960189 0.414618375507279 0.812050497107521 GO:0005164 tumor necrosis factor receptor binding 3/1416 31/18639 0.0967741935483871 1.27385183160197 0.422213054084088 0.824399512895958 GO:0030170 pyridoxal phosphate binding 5/1416 56/18639 0.0892857142857143 1.17527996368039 0.422661125774286 0.824399512895958 GO:0042562 hormone binding 8/1416 94/18639 0.0851063829787234 1.12026685899748 0.423104511909566 0.824399512895958 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 2/1416 19/18639 0.105263157894737 1.38559322033898 0.429070603579668 0.82890300589326 GO:0008381 mechanosensitive monoatomic ion channel activity 2/1416 19/18639 0.105263157894737 1.38559322033898 0.429070603579668 0.82890300589326 GO:0015245 fatty acid transmembrane transporter activity 2/1416 19/18639 0.105263157894737 1.38559322033898 0.429070603579668 0.82890300589326 GO:0030506 ankyrin binding 2/1416 19/18639 0.105263157894737 1.38559322033898 0.429070603579668 0.82890300589326 GO:0050145 nucleoside monophosphate kinase activity 2/1416 19/18639 0.105263157894737 1.38559322033898 0.429070603579668 0.82890300589326 GO:0001046 core promoter sequence-specific DNA binding 4/1416 44/18639 0.0909090909090909 1.19664869029276 0.432072363473936 0.830457729117701 GO:0001223 transcription coactivator binding 4/1416 44/18639 0.0909090909090909 1.19664869029276 0.432072363473936 0.830457729117701 GO:0030020 extracellular matrix structural constituent conferring tensile strength 4/1416 44/18639 0.0909090909090909 1.19664869029276 0.432072363473936 0.830457729117701 GO:0008276 protein methyltransferase activity 8/1416 95/18639 0.0842105263157895 1.10847457627119 0.43488237834463 0.834444360478529 GO:0070279 vitamin B6 binding 5/1416 57/18639 0.087719298245614 1.15466101694915 0.437957174559966 0.838924722890206 GO:0008028 monocarboxylic acid transmembrane transporter activity 6/1416 70/18639 0.0857142857142857 1.12826876513317 0.441857365168794 0.842606440171853 GO:0099106 ion channel regulator activity 13/1416 160/18639 0.08125 1.06950476694915 0.442469678569979 0.842606440171853 GO:0031369 translation initiation factor binding 3/1416 32/18639 0.09375 1.23404396186441 0.442851356562984 0.842606440171853 GO:0042910 xenobiotic transmembrane transporter activity 3/1416 32/18639 0.09375 1.23404396186441 0.442851356562984 0.842606440171853 GO:0046915 transition metal ion transmembrane transporter activity 4/1416 45/18639 0.0888888888888889 1.17005649717514 0.449381137154465 0.853598340926572 GO:0004866 endopeptidase inhibitor activity 13/1416 161/18639 0.0807453416149068 1.06286188019792 0.451532891297679 0.853844262882813 GO:0061980 regulatory RNA binding 5/1416 58/18639 0.0862068965517241 1.13475306838106 0.453158497265079 0.853844262882813 GO:0005326 neurotransmitter transmembrane transporter activity 2/1416 20/18639 0.1 1.31631355932203 0.45553419668792 0.853844262882813 GO:0015095 magnesium ion transmembrane transporter activity 2/1416 20/18639 0.1 1.31631355932203 0.45553419668792 0.853844262882813 GO:0015464 acetylcholine receptor activity 2/1416 20/18639 0.1 1.31631355932203 0.45553419668792 0.853844262882813 GO:0016004 phospholipase activator activity 2/1416 20/18639 0.1 1.31631355932203 0.45553419668792 0.853844262882813 GO:0016505 peptidase activator activity involved in apoptotic process 2/1416 20/18639 0.1 1.31631355932203 0.45553419668792 0.853844262882813 GO:0031418 L-ascorbic acid binding 2/1416 20/18639 0.1 1.31631355932203 0.45553419668792 0.853844262882813 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 3/1416 33/18639 0.0909090909090909 1.19664869029276 0.463193806770449 0.863917396180409 GO:0019956 chemokine binding 3/1416 33/18639 0.0909090909090909 1.19664869029276 0.463193806770449 0.863917396180409 GO:0030296 protein tyrosine kinase activator activity 3/1416 33/18639 0.0909090909090909 1.19664869029276 0.463193806770449 0.863917396180409 GO:0030291 protein serine/threonine kinase inhibitor activity 4/1416 46/18639 0.0869565217391304 1.14462048636699 0.466517964090509 0.868688622789223 GO:0015459 potassium channel regulator activity 5/1416 59/18639 0.0847457627118644 1.11551996552715 0.46824598132298 0.870476955443048 GO:1902936 phosphatidylinositol bisphosphate binding 9/1416 111/18639 0.0810810810810811 1.06728126431516 0.470104297973977 0.872501266616186 GO:0015174 basic amino acid transmembrane transporter activity 2/1416 21/18639 0.0952380952380952 1.25363196125908 0.48127508499542 0.885223725443576 GO:0035613 RNA stem-loop binding 2/1416 21/18639 0.0952380952380952 1.25363196125908 0.48127508499542 0.885223725443576 GO:0051010 microtubule plus-end binding 2/1416 21/18639 0.0952380952380952 1.25363196125908 0.48127508499542 0.885223725443576 GO:0051428 peptide hormone receptor binding 2/1416 21/18639 0.0952380952380952 1.25363196125908 0.48127508499542 0.885223725443576 GO:0061891 calcium ion sensor activity 2/1416 21/18639 0.0952380952380952 1.25363196125908 0.48127508499542 0.885223725443576 GO:0050660 flavin adenine dinucleotide binding 7/1416 86/18639 0.0813953488372093 1.07141801340166 0.482198473364883 0.885223725443576 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 5/1416 60/18639 0.0833333333333333 1.09692796610169 0.483201636292759 0.885223725443576 GO:0015020 glucuronosyltransferase activity 3/1416 34/18639 0.0882352941176471 1.16145314057827 0.483204132318848 0.885223725443576 GO:0000175 3'-5'-RNA exonuclease activity 3/1416 35/18639 0.0857142857142857 1.12826876513317 0.502850389326632 0.908418925095263 GO:0005154 epidermal growth factor receptor binding 3/1416 35/18639 0.0857142857142857 1.12826876513317 0.502850389326632 0.908418925095263 GO:0005243 gap junction channel activity 2/1416 22/18639 0.0909090909090909 1.19664869029276 0.506250300086425 0.908418925095263 GO:0008093 cytoskeletal anchor activity 2/1416 22/18639 0.0909090909090909 1.19664869029276 0.506250300086425 0.908418925095263 GO:0015377 chloride:monoatomic cation symporter activity 2/1416 22/18639 0.0909090909090909 1.19664869029276 0.506250300086425 0.908418925095263 GO:0016881 acid-amino acid ligase activity 2/1416 22/18639 0.0909090909090909 1.19664869029276 0.506250300086425 0.908418925095263 GO:0046972 histone H4K16 acetyltransferase activity 2/1416 22/18639 0.0909090909090909 1.19664869029276 0.506250300086425 0.908418925095263 GO:0140784 metal ion sensor activity 2/1416 22/18639 0.0909090909090909 1.19664869029276 0.506250300086425 0.908418925095263 GO:0019003 GDP binding 6/1416 75/18639 0.08 1.05305084745763 0.509483589774357 0.908418925095263 GO:0015179 L-amino acid transmembrane transporter activity 5/1416 62/18639 0.0806451612903226 1.06154319300164 0.512651141967261 0.908418925095263 GO:0016247 channel regulator activity 13/1416 168/18639 0.0773809523809524 1.018575968523 0.514346781890007 0.908418925095263 GO:0060590 ATPase regulator activity 4/1416 49/18639 0.0816326530612245 1.07454168107921 0.516660172722723 0.908418925095263 GO:0141003 histone H2AX kinase activity 27/1416 354/18639 0.076271186440678 1.00396796897443 0.520765531452052 0.908418925095263 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 2/1416 23/18639 0.0869565217391304 1.14462048636699 0.530427561919906 0.908418925095263 GO:0031681 G-protein beta-subunit binding 2/1416 23/18639 0.0869565217391304 1.14462048636699 0.530427561919906 0.908418925095263 GO:0099186 structural constituent of postsynapse 2/1416 23/18639 0.0869565217391304 1.14462048636699 0.530427561919906 0.908418925095263 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 2/1416 23/18639 0.0869565217391304 1.14462048636699 0.530427561919906 0.908418925095263 GO:0141108 transporter regulator activity 13/1416 170/18639 0.0764705882352941 1.0065927218345 0.531965240879947 0.908418925095263 GO:0032813 tumor necrosis factor receptor superfamily binding 4/1416 50/18639 0.08 1.05305084745763 0.532882617150835 0.908418925095263 GO:0016758 hexosyltransferase activity 15/1416 197/18639 0.0761421319796954 1.00226920760561 0.535308936645285 0.908418925095263 GO:0019955 cytokine binding 11/1416 144/18639 0.0763888888888889 1.00551730225989 0.537782398918925 0.908418925095263 GO:0140996 histone H3 kinase activity 27/1416 357/18639 0.0756302521008403 0.995531263352799 0.539053799910262 0.908418925095263 GO:0043394 proteoglycan binding 3/1416 37/18639 0.0810810810810811 1.06728126431516 0.540943185543206 0.908418925095263 GO:1901981 phosphatidylinositol phosphate binding 14/1416 185/18639 0.0756756756756757 0.996129180027485 0.546268708753999 0.908418925095263 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0004090 carbonyl reductase (NADPH) activity 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0004862 cAMP-dependent protein kinase inhibitor activity 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0004935 adrenergic receptor activity 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0005337 nucleoside transmembrane transporter activity 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0005381 iron ion transmembrane transporter activity 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0005528 FK506 binding 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0008190 eukaryotic initiation factor 4E binding 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0015187 glycine transmembrane transporter activity 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0015643 toxic substance binding 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0019531 oxalate transmembrane transporter activity 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0031956 medium-chain fatty acid-CoA ligase activity 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0031996 thioesterase binding 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0033204 ribonuclease P RNA binding 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0035256 G protein-coupled glutamate receptor binding 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0042166 acetylcholine binding 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0043295 glutathione binding 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0050815 phosphoserine residue binding 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0051378 serotonin binding 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0099122 RNA polymerase II C-terminal domain binding 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0140135 mechanosensitive monoatomic cation channel activity 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0140940 histone H2A methyltransferase activity 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0140999 histone H3K4 trimethyltransferase activity 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:1990259 histone H2AQ104 methyltransferase activity 1/1416 10/18639 0.1 1.31631355932203 0.546292772279685 0.908418925095263 GO:0005540 hyaluronic acid binding 2/1416 24/18639 0.0833333333333333 1.09692796610169 0.553783904790579 0.908418925095263 GO:0015295 solute:proton symporter activity 2/1416 24/18639 0.0833333333333333 1.09692796610169 0.553783904790579 0.908418925095263 GO:0042625 ATPase-coupled ion transmembrane transporter activity 2/1416 24/18639 0.0833333333333333 1.09692796610169 0.553783904790579 0.908418925095263 GO:0043998 histone H2A acetyltransferase activity 2/1416 24/18639 0.0833333333333333 1.09692796610169 0.553783904790579 0.908418925095263 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 2/1416 24/18639 0.0833333333333333 1.09692796610169 0.553783904790579 0.908418925095263 GO:0046961 proton-transporting ATPase activity, rotational mechanism 2/1416 24/18639 0.0833333333333333 1.09692796610169 0.553783904790579 0.908418925095263 GO:0060229 lipase activator activity 2/1416 24/18639 0.0833333333333333 1.09692796610169 0.553783904790579 0.908418925095263 GO:0000146 microfilament motor activity 3/1416 38/18639 0.0789473684210526 1.03919491525424 0.559345390383381 0.908418925095263 GO:0005109 frizzled binding 3/1416 38/18639 0.0789473684210526 1.03919491525424 0.559345390383381 0.908418925095263 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 3/1416 38/18639 0.0789473684210526 1.03919491525424 0.559345390383381 0.908418925095263 GO:0033293 monocarboxylic acid binding 6/1416 79/18639 0.0759493670886076 0.999731817206608 0.561290300065834 0.908418925095263 GO:0008234 cysteine-type peptidase activity 14/1416 187/18639 0.0748663101604278 0.985475392005801 0.562877299944189 0.908418925095263 GO:0051213 dioxygenase activity 7/1416 93/18639 0.0752688172043011 0.990773646801531 0.566578730642709 0.908418925095263 GO:0016741 transferase activity, transferring one-carbon groups 16/1416 215/18639 0.0744186046511628 0.979582183681514 0.57184557964338 0.908418925095263 GO:0000049 tRNA binding 6/1416 80/18639 0.075 0.987235169491525 0.573834707172578 0.908418925095263 GO:0000030 mannosyltransferase activity 2/1416 25/18639 0.08 1.05305084745763 0.576304450141435 0.908418925095263 GO:0005537 D-mannose binding 2/1416 25/18639 0.08 1.05305084745763 0.576304450141435 0.908418925095263 GO:0008139 nuclear localization sequence binding 2/1416 25/18639 0.08 1.05305084745763 0.576304450141435 0.908418925095263 GO:0015296 monoatomic anion:monoatomic cation symporter activity 2/1416 25/18639 0.08 1.05305084745763 0.576304450141435 0.908418925095263 GO:0005544 calcium-dependent phospholipid binding 4/1416 53/18639 0.0754716981132075 0.993444195714743 0.579839247265819 0.908418925095263 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0004143 ATP-dependent diacylglycerol kinase activity 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0005114 type II transforming growth factor beta receptor binding 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0005536 D-glucose binding 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0008199 ferric iron binding 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0008503 benzodiazepine receptor activity 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0008526 phosphatidylinositol transfer activity 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0016594 glycine binding 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0019107 myristoyltransferase activity 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0019215 intermediate filament binding 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0034713 type I transforming growth factor beta receptor binding 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0035252 UDP-xylosyltransferase activity 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0042285 xylosyltransferase activity 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0042608 T cell receptor binding 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0048185 activin binding 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0099528 G protein-coupled neurotransmitter receptor activity 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0140031 phosphorylation-dependent protein binding 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0140537 transcription regulator activator activity 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:1900750 oligopeptide binding 1/1416 11/18639 0.0909090909090909 1.19664869029276 0.580779295144679 0.908418925095263 GO:0042054 histone methyltransferase activity 5/1416 67/18639 0.0746268656716418 0.982323551732861 0.582924762465374 0.910518843850873 GO:0008509 monoatomic anion transmembrane transporter activity 11/1416 149/18639 0.0738255033557047 0.971775110908884 0.584313925373494 0.910538374185105 GO:0004177 aminopeptidase activity 3/1416 40/18639 0.075 0.987235169491525 0.594776336166023 0.910538374185105 GO:0004532 RNA exonuclease activity 3/1416 40/18639 0.075 0.987235169491525 0.594776336166023 0.910538374185105 GO:0050997 quaternary ammonium group binding 3/1416 40/18639 0.075 0.987235169491525 0.594776336166023 0.910538374185105 GO:0005112 Notch binding 2/1416 26/18639 0.0769230769230769 1.01254889178618 0.59798131186932 0.910538374185105 GO:0005160 transforming growth factor beta receptor binding 2/1416 26/18639 0.0769230769230769 1.01254889178618 0.59798131186932 0.910538374185105 GO:0008143 poly(A) binding 2/1416 26/18639 0.0769230769230769 1.01254889178618 0.59798131186932 0.910538374185105 GO:0030507 spectrin binding 2/1416 26/18639 0.0769230769230769 1.01254889178618 0.59798131186932 0.910538374185105 GO:0070006 metalloaminopeptidase activity 2/1416 26/18639 0.0769230769230769 1.01254889178618 0.59798131186932 0.910538374185105 GO:0070412 R-SMAD binding 2/1416 26/18639 0.0769230769230769 1.01254889178618 0.59798131186932 0.910538374185105 GO:0097602 cullin family protein binding 2/1416 26/18639 0.0769230769230769 1.01254889178618 0.59798131186932 0.910538374185105 GO:0120014 phospholipid transfer activity 2/1416 26/18639 0.0769230769230769 1.01254889178618 0.59798131186932 0.910538374185105 GO:0016791 phosphatase activity 20/1416 273/18639 0.0732600732600733 0.9643322778916 0.600930038687291 0.910538374185105 GO:0004222 metalloendopeptidase activity 8/1416 110/18639 0.0727272727272727 0.957318952234206 0.603296678074034 0.910538374185105 GO:0015103 inorganic anion transmembrane transporter activity 12/1416 165/18639 0.0727272727272727 0.957318952234206 0.605379321555134 0.910538374185105 GO:0140313 molecular sequestering activity 4/1416 55/18639 0.0727272727272727 0.957318952234206 0.609589705782178 0.910538374185105 GO:0046982 protein heterodimerization activity 27/1416 369/18639 0.0731707317073171 0.963156262918561 0.610021281074029 0.910538374185105 GO:0001540 amyloid-beta binding 6/1416 83/18639 0.072289156626506 0.951551970594241 0.610356917474675 0.910538374185105 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 6/1416 83/18639 0.072289156626506 0.951551970594241 0.610356917474675 0.910538374185105 GO:0030165 PDZ domain binding 6/1416 83/18639 0.072289156626506 0.951551970594241 0.610356917474675 0.910538374185105 GO:0001530 lipopolysaccharide binding 3/1416 41/18639 0.0731707317073171 0.963156262918561 0.61178035714871 0.910538374185105 GO:0042169 SH2 domain binding 3/1416 41/18639 0.0731707317073171 0.963156262918561 0.61178035714871 0.910538374185105 GO:0042287 MHC protein binding 3/1416 41/18639 0.0731707317073171 0.963156262918561 0.61178035714871 0.910538374185105 GO:0004526 ribonuclease P activity 1/1416 12/18639 0.0833333333333333 1.09692796610169 0.612646190038126 0.910538374185105 GO:0005527 macrolide binding 1/1416 12/18639 0.0833333333333333 1.09692796610169 0.612646190038126 0.910538374185105 GO:0008179 adenylate cyclase binding 1/1416 12/18639 0.0833333333333333 1.09692796610169 0.612646190038126 0.910538374185105 GO:0008504 monoamine transmembrane transporter activity 1/1416 12/18639 0.0833333333333333 1.09692796610169 0.612646190038126 0.910538374185105 GO:0008603 cAMP-dependent protein kinase regulator activity 1/1416 12/18639 0.0833333333333333 1.09692796610169 0.612646190038126 0.910538374185105 GO:0015132 prostaglandin transmembrane transporter activity 1/1416 12/18639 0.0833333333333333 1.09692796610169 0.612646190038126 0.910538374185105 GO:0015269 calcium-activated potassium channel activity 1/1416 12/18639 0.0833333333333333 1.09692796610169 0.612646190038126 0.910538374185105 GO:0016208 AMP binding 1/1416 12/18639 0.0833333333333333 1.09692796610169 0.612646190038126 0.910538374185105 GO:0016840 carbon-nitrogen lyase activity 1/1416 12/18639 0.0833333333333333 1.09692796610169 0.612646190038126 0.910538374185105 GO:0036009 protein-glutamine N-methyltransferase activity 1/1416 12/18639 0.0833333333333333 1.09692796610169 0.612646190038126 0.910538374185105 GO:0070008 serine-type exopeptidase activity 1/1416 12/18639 0.0833333333333333 1.09692796610169 0.612646190038126 0.910538374185105 GO:0097677 STAT family protein binding 1/1416 12/18639 0.0833333333333333 1.09692796610169 0.612646190038126 0.910538374185105 GO:0141221 histone deacetylase activity, hydrolytic mechanism 1/1416 12/18639 0.0833333333333333 1.09692796610169 0.612646190038126 0.910538374185105 GO:1990459 transferrin receptor binding 1/1416 12/18639 0.0833333333333333 1.09692796610169 0.612646190038126 0.910538374185105 GO:0003730 mRNA 3'-UTR binding 19/1416 262/18639 0.0725190839694656 0.954578535386208 0.618056747050353 0.916101191023288 GO:0001671 ATPase activator activity 2/1416 27/18639 0.0740740740740741 0.975047080979284 0.618812621096859 0.916101191023288 GO:0008320 protein transmembrane transporter activity 2/1416 27/18639 0.0740740740740741 0.975047080979284 0.618812621096859 0.916101191023288 GO:0016782 transferase activity, transferring sulphur-containing groups 5/1416 70/18639 0.0714285714285714 0.94022397094431 0.622347945653672 0.917043686078926 GO:0170055 lipid transmembrane transporter activity 4/1416 56/18639 0.0714285714285714 0.94022397094431 0.623968827321246 0.917043686078926 GO:0042056 chemoattractant activity 3/1416 42/18639 0.0714285714285714 0.94022397094431 0.628298232139523 0.917043686078926 GO:0019783 ubiquitin-like protein peptidase activity 9/1416 127/18639 0.0708661417322835 0.932820632590418 0.63475230065538 0.917043686078926 GO:0016866 intramolecular transferase activity 2/1416 28/18639 0.0714285714285714 0.94022397094431 0.638801658596594 0.917043686078926 GO:0036408 histone H3K14 acetyltransferase activity 2/1416 28/18639 0.0714285714285714 0.94022397094431 0.638801658596594 0.917043686078926 GO:0046625 sphingolipid binding 2/1416 28/18639 0.0714285714285714 0.94022397094431 0.638801658596594 0.917043686078926 GO:0046875 ephrin receptor binding 2/1416 28/18639 0.0714285714285714 0.94022397094431 0.638801658596594 0.917043686078926 GO:0046966 nuclear thyroid hormone receptor binding 2/1416 28/18639 0.0714285714285714 0.94022397094431 0.638801658596594 0.917043686078926 GO:0050698 proteoglycan sulfotransferase activity 2/1416 28/18639 0.0714285714285714 0.94022397094431 0.638801658596594 0.917043686078926 GO:0051019 mitogen-activated protein kinase binding 2/1416 28/18639 0.0714285714285714 0.94022397094431 0.638801658596594 0.917043686078926 GO:0106310 protein serine kinase activity 26/1416 361/18639 0.07202216066482 0.948037466547725 0.641534841039787 0.917043686078926 GO:0002161 aminoacyl-tRNA editing activity 1/1416 13/18639 0.0769230769230769 1.01254889178618 0.642092316355086 0.917043686078926 GO:0003964 RNA-directed DNA polymerase activity 1/1416 13/18639 0.0769230769230769 1.01254889178618 0.642092316355086 0.917043686078926 GO:0004535 poly(A)-specific ribonuclease activity 1/1416 13/18639 0.0769230769230769 1.01254889178618 0.642092316355086 0.917043686078926 GO:0005338 nucleotide-sugar transmembrane transporter activity 1/1416 13/18639 0.0769230769230769 1.01254889178618 0.642092316355086 0.917043686078926 GO:0008035 high-density lipoprotein particle binding 1/1416 13/18639 0.0769230769230769 1.01254889178618 0.642092316355086 0.917043686078926 GO:0008417 fucosyltransferase activity 1/1416 13/18639 0.0769230769230769 1.01254889178618 0.642092316355086 0.917043686078926 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/1416 13/18639 0.0769230769230769 1.01254889178618 0.642092316355086 0.917043686078926 GO:0030955 potassium ion binding 1/1416 13/18639 0.0769230769230769 1.01254889178618 0.642092316355086 0.917043686078926 GO:0031432 titin binding 1/1416 13/18639 0.0769230769230769 1.01254889178618 0.642092316355086 0.917043686078926 GO:0045159 myosin II binding 1/1416 13/18639 0.0769230769230769 1.01254889178618 0.642092316355086 0.917043686078926 GO:0046975 histone H3K36 methyltransferase activity 1/1416 13/18639 0.0769230769230769 1.01254889178618 0.642092316355086 0.917043686078926 GO:0070123 transforming growth factor beta receptor activity, type III 1/1416 13/18639 0.0769230769230769 1.01254889178618 0.642092316355086 0.917043686078926 GO:0070700 BMP receptor binding 1/1416 13/18639 0.0769230769230769 1.01254889178618 0.642092316355086 0.917043686078926 GO:0071714 icosanoid transmembrane transporter activity 1/1416 13/18639 0.0769230769230769 1.01254889178618 0.642092316355086 0.917043686078926 GO:0071837 HMG box domain binding 1/1416 13/18639 0.0769230769230769 1.01254889178618 0.642092316355086 0.917043686078926 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/1416 13/18639 0.0769230769230769 1.01254889178618 0.642092316355086 0.917043686078926 GO:0008375 acetylglucosaminyltransferase activity 3/1416 43/18639 0.0697674418604651 0.918358297201419 0.644324221386941 0.917919179714561 GO:0048156 tau protein binding 3/1416 43/18639 0.0697674418604651 0.918358297201419 0.644324221386941 0.917919179714561 GO:0101005 deubiquitinase activity 8/1416 115/18639 0.0695652173913043 0.915696389093589 0.653554768644944 0.929901013354287 GO:0004629 phospholipase C activity 2/1416 29/18639 0.0689655172413793 0.907802454704851 0.65795608415679 0.93127342535964 GO:0016417 S-acyltransferase activity 2/1416 29/18639 0.0689655172413793 0.907802454704851 0.65795608415679 0.93127342535964 GO:0043014 alpha-tubulin binding 3/1416 44/18639 0.0681818181818182 0.897486517719569 0.659854845136673 0.93127342535964 GO:0004674 protein serine/threonine kinase activity 31/1416 433/18639 0.0715935334872979 0.942395388891064 0.662478246931579 0.93127342535964 GO:0008238 exopeptidase activity 7/1416 102/18639 0.0686274509803922 0.903352442671984 0.664622264116604 0.93127342535964 GO:0045309 protein phosphorylated amino acid binding 4/1416 59/18639 0.0677966101694915 0.892415972421718 0.66504206442389 0.93127342535964 GO:0004065 arylsulfatase activity 1/1416 14/18639 0.0714285714285714 0.94022397094431 0.669301447679106 0.93127342535964 GO:0005161 platelet-derived growth factor receptor binding 1/1416 14/18639 0.0714285714285714 0.94022397094431 0.669301447679106 0.93127342535964 GO:0005545 1-phosphatidylinositol binding 1/1416 14/18639 0.0714285714285714 0.94022397094431 0.669301447679106 0.93127342535964 GO:0008191 metalloendopeptidase inhibitor activity 1/1416 14/18639 0.0714285714285714 0.94022397094431 0.669301447679106 0.93127342535964 GO:0008195 phosphatidate phosphatase activity 1/1416 14/18639 0.0714285714285714 0.94022397094431 0.669301447679106 0.93127342535964 GO:0008494 translation activator activity 1/1416 14/18639 0.0714285714285714 0.94022397094431 0.669301447679106 0.93127342535964 GO:0015386 potassium:proton antiporter activity 1/1416 14/18639 0.0714285714285714 0.94022397094431 0.669301447679106 0.93127342535964 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/1416 14/18639 0.0714285714285714 0.94022397094431 0.669301447679106 0.93127342535964 GO:0034236 protein kinase A catalytic subunit binding 1/1416 14/18639 0.0714285714285714 0.94022397094431 0.669301447679106 0.93127342535964 GO:0042813 Wnt receptor activity 1/1416 14/18639 0.0714285714285714 0.94022397094431 0.669301447679106 0.93127342535964 GO:0043176 amine binding 1/1416 14/18639 0.0714285714285714 0.94022397094431 0.669301447679106 0.93127342535964 GO:1901474 azole transmembrane transporter activity 1/1416 14/18639 0.0714285714285714 0.94022397094431 0.669301447679106 0.93127342535964 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 16/1416 229/18639 0.0698689956331878 0.91969506328177 0.673150626307108 0.934116620108731 GO:0001965 G-protein alpha-subunit binding 2/1416 30/18639 0.0666666666666667 0.877542372881356 0.676287253182776 0.934116620108731 GO:0031210 phosphatidylcholine binding 2/1416 30/18639 0.0666666666666667 0.877542372881356 0.676287253182776 0.934116620108731 GO:0031624 ubiquitin conjugating enzyme binding 2/1416 30/18639 0.0666666666666667 0.877542372881356 0.676287253182776 0.934116620108731 GO:0051721 protein phosphatase 2A binding 2/1416 30/18639 0.0666666666666667 0.877542372881356 0.676287253182776 0.934116620108731 GO:0098918 structural constituent of synapse 2/1416 30/18639 0.0666666666666667 0.877542372881356 0.676287253182776 0.934116620108731 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 4/1416 60/18639 0.0666666666666667 0.877542372881356 0.678030666433256 0.935385371940769 GO:0005452 solute:inorganic anion antiporter activity 2/1416 31/18639 0.0645161290322581 0.849234554401312 0.693809611741306 0.941984250169644 GO:0017147 Wnt-protein binding 2/1416 31/18639 0.0645161290322581 0.849234554401312 0.693809611741306 0.941984250169644 GO:0070273 phosphatidylinositol-4-phosphate binding 2/1416 31/18639 0.0645161290322581 0.849234554401312 0.693809611741306 0.941984250169644 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1/1416 15/18639 0.0666666666666667 0.877542372881356 0.694443415468979 0.941984250169644 GO:0005523 tropomyosin binding 1/1416 15/18639 0.0666666666666667 0.877542372881356 0.694443415468979 0.941984250169644 GO:0008242 omega peptidase activity 1/1416 15/18639 0.0666666666666667 0.877542372881356 0.694443415468979 0.941984250169644 GO:0010181 FMN binding 1/1416 15/18639 0.0666666666666667 0.877542372881356 0.694443415468979 0.941984250169644 GO:0015929 hexosaminidase activity 1/1416 15/18639 0.0666666666666667 0.877542372881356 0.694443415468979 0.941984250169644 GO:0016846 carbon-sulfur lyase activity 1/1416 15/18639 0.0666666666666667 0.877542372881356 0.694443415468979 0.941984250169644 GO:0034483 heparan sulfate sulfotransferase activity 1/1416 15/18639 0.0666666666666667 0.877542372881356 0.694443415468979 0.941984250169644 GO:0045504 dynein heavy chain binding 1/1416 15/18639 0.0666666666666667 0.877542372881356 0.694443415468979 0.941984250169644 GO:0047372 monoacylglycerol lipase activity 1/1416 15/18639 0.0666666666666667 0.877542372881356 0.694443415468979 0.941984250169644 GO:0141050 histone H3K deacetylase activity 1/1416 15/18639 0.0666666666666667 0.877542372881356 0.694443415468979 0.941984250169644 GO:0141051 histone H4K deacetylase activity 1/1416 15/18639 0.0666666666666667 0.877542372881356 0.694443415468979 0.941984250169644 GO:0003924 GTPase activity 23/1416 331/18639 0.0694864048338369 0.914658968713196 0.703222622299125 0.950625309753412 GO:0001784 phosphotyrosine residue binding 3/1416 47/18639 0.0638297872340425 0.840200144248107 0.703469446094408 0.950625309753412 GO:0043495 protein-membrane adaptor activity 3/1416 47/18639 0.0638297872340425 0.840200144248107 0.703469446094408 0.950625309753412 GO:0003724 RNA helicase activity 5/1416 77/18639 0.0649350649350649 0.854749064494827 0.705130315826991 0.950625309753412 GO:0052689 carboxylic ester hydrolase activity 6/1416 92/18639 0.0652173913043478 0.858465364775239 0.708621817841475 0.950625309753412 GO:0015081 sodium ion transmembrane transporter activity 11/1416 164/18639 0.0670731707317073 0.882893241008681 0.7094448107886 0.950625309753412 GO:0008378 galactosyltransferase activity 2/1416 32/18639 0.0625 0.822695974576271 0.710540162086528 0.950625309753412 GO:0015106 bicarbonate transmembrane transporter activity 2/1416 32/18639 0.0625 0.822695974576271 0.710540162086528 0.950625309753412 GO:0022884 macromolecule transmembrane transporter activity 2/1416 32/18639 0.0625 0.822695974576271 0.710540162086528 0.950625309753412 GO:0070717 poly-purine tract binding 2/1416 32/18639 0.0625 0.822695974576271 0.710540162086528 0.950625309753412 GO:0140693 molecular condensate scaffold activity 3/1416 48/18639 0.0625 0.822695974576271 0.717022134220987 0.950625309753412 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 1/1416 16/18639 0.0625 0.822695974576271 0.717675166096982 0.950625309753412 GO:0005149 interleukin-1 receptor binding 1/1416 16/18639 0.0625 0.822695974576271 0.717675166096982 0.950625309753412 GO:0005521 lamin binding 1/1416 16/18639 0.0625 0.822695974576271 0.717675166096982 0.950625309753412 GO:0015378 sodium:chloride symporter activity 1/1416 16/18639 0.0625 0.822695974576271 0.717675166096982 0.950625309753412 GO:0015385 sodium:proton antiporter activity 1/1416 16/18639 0.0625 0.822695974576271 0.717675166096982 0.950625309753412 GO:0015562 efflux transmembrane transporter activity 1/1416 16/18639 0.0625 0.822695974576271 0.717675166096982 0.950625309753412 GO:0031435 mitogen-activated protein kinase kinase kinase binding 1/1416 16/18639 0.0625 0.822695974576271 0.717675166096982 0.950625309753412 GO:0097027 ubiquitin-protein transferase activator activity 1/1416 16/18639 0.0625 0.822695974576271 0.717675166096982 0.950625309753412 GO:0140327 flippase activity 1/1416 16/18639 0.0625 0.822695974576271 0.717675166096982 0.950625309753412 GO:0051219 phosphoprotein binding 6/1416 93/18639 0.0645161290322581 0.849234554401312 0.7184178928207 0.950625309753412 GO:0004843 cysteine-type deubiquitinase activity 7/1416 108/18639 0.0648148148148148 0.853166195856874 0.721827577549671 0.952913239745432 GO:0005496 steroid binding 7/1416 108/18639 0.0648148148148148 0.853166195856874 0.721827577549671 0.952913239745432 GO:0008186 ATP-dependent activity, acting on RNA 5/1416 79/18639 0.0632911392405063 0.833109847672173 0.726296817359351 0.956586052131828 GO:0046332 SMAD binding 5/1416 79/18639 0.0632911392405063 0.833109847672173 0.726296817359351 0.956586052131828 GO:0001222 transcription corepressor binding 3/1416 49/18639 0.0612244897959184 0.805906260809409 0.730089218666527 0.959588517556949 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 11/1416 167/18639 0.0658682634730539 0.867032883385771 0.73137706039984 0.959588517556949 GO:0008429 phosphatidylethanolamine binding 1/1416 17/18639 0.0588235294117647 0.774302093718844 0.739141737799 0.959588517556949 GO:0008484 sulfuric ester hydrolase activity 1/1416 17/18639 0.0588235294117647 0.774302093718844 0.739141737799 0.959588517556949 GO:0015278 intracellularly gated calcium channel activity 1/1416 17/18639 0.0588235294117647 0.774302093718844 0.739141737799 0.959588517556949 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/1416 17/18639 0.0588235294117647 0.774302093718844 0.739141737799 0.959588517556949 GO:0016805 dipeptidase activity 1/1416 17/18639 0.0588235294117647 0.774302093718844 0.739141737799 0.959588517556949 GO:0030548 acetylcholine receptor regulator activity 1/1416 17/18639 0.0588235294117647 0.774302093718844 0.739141737799 0.959588517556949 GO:0031489 myosin V binding 1/1416 17/18639 0.0588235294117647 0.774302093718844 0.739141737799 0.959588517556949 GO:0036041 long-chain fatty acid binding 1/1416 17/18639 0.0588235294117647 0.774302093718844 0.739141737799 0.959588517556949 GO:0038191 neuropilin binding 1/1416 17/18639 0.0588235294117647 0.774302093718844 0.739141737799 0.959588517556949 GO:0070492 oligosaccharide binding 1/1416 17/18639 0.0588235294117647 0.774302093718844 0.739141737799 0.959588517556949 GO:0051427 hormone receptor binding 2/1416 34/18639 0.0588235294117647 0.774302093718844 0.741703857658191 0.959588517556949 GO:0033192 calmodulin-dependent protein phosphatase activity 5/1416 81/18639 0.0617283950617284 0.812539234149404 0.746346624766516 0.959588517556949 GO:0140791 histone H2AXS140 phosphatase activity 5/1416 81/18639 0.0617283950617284 0.812539234149404 0.746346624766516 0.959588517556949 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 5/1416 81/18639 0.0617283950617284 0.812539234149404 0.746346624766516 0.959588517556949 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 5/1416 81/18639 0.0617283950617284 0.812539234149404 0.746346624766516 0.959588517556949 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 5/1416 81/18639 0.0617283950617284 0.812539234149404 0.746346624766516 0.959588517556949 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 5/1416 81/18639 0.0617283950617284 0.812539234149404 0.746346624766516 0.959588517556949 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 5/1416 81/18639 0.0617283950617284 0.812539234149404 0.746346624766516 0.959588517556949 GO:1990439 MAP kinase serine/threonine phosphatase activity 5/1416 81/18639 0.0617283950617284 0.812539234149404 0.746346624766516 0.959588517556949 GO:0008237 metallopeptidase activity 12/1416 184/18639 0.0652173913043478 0.858465364775239 0.749377352384297 0.962394017671339 GO:0035091 phosphatidylinositol binding 19/1416 284/18639 0.0669014084507042 0.880632310814037 0.751074333890977 0.962729422285271 GO:0005048 signal sequence binding 3/1416 51/18639 0.0588235294117647 0.774302093718844 0.754792325952671 0.962729422285271 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 5/1416 82/18639 0.0609756097560976 0.802630219098801 0.755955161091558 0.962729422285271 GO:0033549 MAP kinase phosphatase activity 5/1416 82/18639 0.0609756097560976 0.802630219098801 0.755955161091558 0.962729422285271 GO:0008525 phosphatidylcholine transporter activity 1/1416 18/18639 0.0555555555555556 0.731285310734463 0.758977163600558 0.962729422285271 GO:0015172 acidic amino acid transmembrane transporter activity 1/1416 18/18639 0.0555555555555556 0.731285310734463 0.758977163600558 0.962729422285271 GO:0015373 monoatomic anion:sodium symporter activity 1/1416 18/18639 0.0555555555555556 0.731285310734463 0.758977163600558 0.962729422285271 GO:0016854 racemase and epimerase activity 1/1416 18/18639 0.0555555555555556 0.731285310734463 0.758977163600558 0.962729422285271 GO:0017075 syntaxin-1 binding 1/1416 18/18639 0.0555555555555556 0.731285310734463 0.758977163600558 0.962729422285271 GO:0022851 GABA-gated chloride ion channel activity 1/1416 18/18639 0.0555555555555556 0.731285310734463 0.758977163600558 0.962729422285271 GO:0099602 neurotransmitter receptor regulator activity 1/1416 18/18639 0.0555555555555556 0.731285310734463 0.758977163600558 0.962729422285271 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 2/1416 36/18639 0.0555555555555556 0.731285310734463 0.769948948479348 0.970847882662324 GO:0016409 palmitoyltransferase activity 2/1416 36/18639 0.0555555555555556 0.731285310734463 0.769948948479348 0.970847882662324 GO:0004860 protein kinase inhibitor activity 5/1416 84/18639 0.0595238095238095 0.783519975786925 0.774348537603101 0.970847882662324 GO:0017018 myosin phosphatase activity 5/1416 84/18639 0.0595238095238095 0.783519975786925 0.774348537603101 0.970847882662324 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/1416 19/18639 0.0526315789473684 0.692796610169492 0.77730530582394 0.970847882662324 GO:0004890 GABA-A receptor activity 1/1416 19/18639 0.0526315789473684 0.692796610169492 0.77730530582394 0.970847882662324 GO:0022821 solute:potassium antiporter activity 1/1416 19/18639 0.0526315789473684 0.692796610169492 0.77730530582394 0.970847882662324 GO:0042577 lipid phosphatase activity 1/1416 19/18639 0.0526315789473684 0.692796610169492 0.77730530582394 0.970847882662324 GO:0042800 histone H3K4 methyltransferase activity 1/1416 19/18639 0.0526315789473684 0.692796610169492 0.77730530582394 0.970847882662324 GO:0043395 heparan sulfate proteoglycan binding 1/1416 19/18639 0.0526315789473684 0.692796610169492 0.77730530582394 0.970847882662324 GO:0046624 sphingolipid transporter activity 1/1416 19/18639 0.0526315789473684 0.692796610169492 0.77730530582394 0.970847882662324 GO:0097001 ceramide binding 1/1416 19/18639 0.0526315789473684 0.692796610169492 0.77730530582394 0.970847882662324 GO:1990380 K48-linked deubiquitinase activity 1/1416 19/18639 0.0526315789473684 0.692796610169492 0.77730530582394 0.970847882662324 GO:0008146 sulfotransferase activity 3/1416 53/18639 0.0566037735849057 0.745083146786057 0.777639985645901 0.970847882662324 GO:0017124 SH3 domain binding 7/1416 115/18639 0.0608695652173913 0.80123434045689 0.779679086842221 0.970847882662324 GO:0016798 hydrolase activity, acting on glycosyl bonds 8/1416 130/18639 0.0615384615384615 0.810039113428944 0.779931588276346 0.970847882662324 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 8/1416 130/18639 0.0615384615384615 0.810039113428944 0.779931588276346 0.970847882662324 GO:0008194 UDP-glycosyltransferase activity 9/1416 145/18639 0.0620689655172414 0.817022209234366 0.780944238814225 0.97104250747295 GO:0030280 structural constituent of skin epidermis 2/1416 37/18639 0.0540540540540541 0.711520842876775 0.783034992075699 0.971824666136107 GO:0008168 methyltransferase activity 13/1416 204/18639 0.0637254901960784 0.838827268195414 0.783287252952735 0.971824666136107 GO:0015485 cholesterol binding 3/1416 54/18639 0.0555555555555556 0.731285310734463 0.788390747067215 0.973493467834091 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 3/1416 54/18639 0.0555555555555556 0.731285310734463 0.788390747067215 0.973493467834091 GO:0042578 phosphoric ester hydrolase activity 24/1416 363/18639 0.0661157024793388 0.870289956576551 0.790097372934092 0.973493467834091 GO:0042277 peptide binding 16/1416 249/18639 0.0642570281124498 0.845823973861548 0.791694023966202 0.973493467834091 GO:0001972 retinoic acid binding 1/1416 20/18639 0.05 0.658156779661017 0.794240627357415 0.973493467834091 GO:0016408 C-acyltransferase activity 1/1416 20/18639 0.05 0.658156779661017 0.794240627357415 0.973493467834091 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/1416 20/18639 0.05 0.658156779661017 0.794240627357415 0.973493467834091 GO:0030742 GTP-dependent protein binding 1/1416 20/18639 0.05 0.658156779661017 0.794240627357415 0.973493467834091 GO:0052745 inositol phosphate phosphatase activity 1/1416 20/18639 0.05 0.658156779661017 0.794240627357415 0.973493467834091 GO:0140939 histone H4 methyltransferase activity 1/1416 20/18639 0.05 0.658156779661017 0.794240627357415 0.973493467834091 GO:0008374 O-acyltransferase activity 3/1416 55/18639 0.0545454545454545 0.717989214175655 0.798706191756736 0.973493467834091 GO:0004722 protein serine/threonine phosphatase activity 6/1416 103/18639 0.058252427184466 0.766784597663321 0.803781257361228 0.973493467834091 GO:0005253 monoatomic anion channel activity 6/1416 103/18639 0.058252427184466 0.766784597663321 0.803781257361228 0.973493467834091 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 3/1416 56/18639 0.0535714285714286 0.705167978208232 0.808596985970066 0.973493467834091 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1/1416 21/18639 0.0476190476190476 0.62681598062954 0.809888904475515 0.973493467834091 GO:0005123 death receptor binding 1/1416 21/18639 0.0476190476190476 0.62681598062954 0.809888904475515 0.973493467834091 GO:0015125 bile acid transmembrane transporter activity 1/1416 21/18639 0.0476190476190476 0.62681598062954 0.809888904475515 0.973493467834091 GO:0036122 BMP binding 1/1416 21/18639 0.0476190476190476 0.62681598062954 0.809888904475515 0.973493467834091 GO:0005543 phospholipid binding 33/1416 497/18639 0.0663983903420523 0.874011015244007 0.81547518528002 0.973493467834091 GO:0019210 kinase inhibitor activity 5/1416 90/18639 0.0555555555555556 0.731285310734463 0.823147604007396 0.973493467834091 GO:0004407 histone deacetylase activity 1/1416 22/18639 0.0454545454545455 0.598324345146379 0.8243478856369 0.973493467834091 GO:0008649 rRNA methyltransferase activity 1/1416 22/18639 0.0454545454545455 0.598324345146379 0.8243478856369 0.973493467834091 GO:0032931 histone H3K56 acetyltransferase activity 1/1416 22/18639 0.0454545454545455 0.598324345146379 0.8243478856369 0.973493467834091 GO:0033558 protein lysine deacetylase activity 1/1416 22/18639 0.0454545454545455 0.598324345146379 0.8243478856369 0.973493467834091 GO:0033691 sialic acid binding 1/1416 22/18639 0.0454545454545455 0.598324345146379 0.8243478856369 0.973493467834091 GO:0043992 histone H3K9 acetyltransferase activity 1/1416 22/18639 0.0454545454545455 0.598324345146379 0.8243478856369 0.973493467834091 GO:0043993 histone H3K18 acetyltransferase activity 1/1416 22/18639 0.0454545454545455 0.598324345146379 0.8243478856369 0.973493467834091 GO:0043994 histone H3K23 acetyltransferase activity 1/1416 22/18639 0.0454545454545455 0.598324345146379 0.8243478856369 0.973493467834091 GO:0043999 histone H2AK5 acetyltransferase activity 1/1416 22/18639 0.0454545454545455 0.598324345146379 0.8243478856369 0.973493467834091 GO:0044012 histone H2AK9 acetyltransferase activity 1/1416 22/18639 0.0454545454545455 0.598324345146379 0.8243478856369 0.973493467834091 GO:0044014 histone H2BK5 acetyltransferase activity 1/1416 22/18639 0.0454545454545455 0.598324345146379 0.8243478856369 0.973493467834091 GO:0044015 histone H2BK12 acetyltransferase activity 1/1416 22/18639 0.0454545454545455 0.598324345146379 0.8243478856369 0.973493467834091 GO:0044016 histone H3K4 acetyltransferase activity 1/1416 22/18639 0.0454545454545455 0.598324345146379 0.8243478856369 0.973493467834091 GO:0044017 histone H3K27 acetyltransferase activity 1/1416 22/18639 0.0454545454545455 0.598324345146379 0.8243478856369 0.973493467834091 GO:0044018 histone H3K36 acetyltransferase activity 1/1416 22/18639 0.0454545454545455 0.598324345146379 0.8243478856369 0.973493467834091 GO:0140908 histone H3K122 acetyltransferase activity 1/1416 22/18639 0.0454545454545455 0.598324345146379 0.8243478856369 0.973493467834091 GO:0046906 tetrapyrrole binding 9/1416 152/18639 0.0592105263157895 0.779396186440678 0.824654525860101 0.973493467834091 GO:0005096 GTPase activator activity 17/1416 271/18639 0.0627306273062731 0.825731753080243 0.82683122854774 0.973493467834091 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 15/1416 243/18639 0.0617283950617284 0.812539234149404 0.832560357955439 0.973493467834091 GO:0004022 alcohol dehydrogenase (NAD+) activity 1/1416 23/18639 0.0434782608695652 0.572310243183493 0.837707900351309 0.973493467834091 GO:0005283 amino acid:sodium symporter activity 1/1416 23/18639 0.0434782608695652 0.572310243183493 0.837707900351309 0.973493467834091 GO:0016917 GABA receptor activity 1/1416 23/18639 0.0434782608695652 0.572310243183493 0.837707900351309 0.973493467834091 GO:0043274 phospholipase binding 1/1416 23/18639 0.0434782608695652 0.572310243183493 0.837707900351309 0.973493467834091 GO:0044013 histone H2B acetyltransferase activity 1/1416 23/18639 0.0434782608695652 0.572310243183493 0.837707900351309 0.973493467834091 GO:0140102 catalytic activity, acting on a rRNA 1/1416 23/18639 0.0434782608695652 0.572310243183493 0.837707900351309 0.973493467834091 GO:0017022 myosin binding 4/1416 76/18639 0.0526315789473684 0.692796610169492 0.838771581786544 0.973493467834091 GO:0019894 kinesin binding 2/1416 42/18639 0.0476190476190476 0.62681598062954 0.839072858754967 0.973493467834091 GO:0051879 Hsp90 protein binding 2/1416 42/18639 0.0476190476190476 0.62681598062954 0.839072858754967 0.973493467834091 GO:0004175 endopeptidase activity 26/1416 405/18639 0.0641975308641975 0.84504080351538 0.841289868869561 0.973493467834091 GO:0004676 3-phosphoinositide-dependent protein kinase activity 15/1416 245/18639 0.0612244897959184 0.805906260809409 0.841290651214647 0.973493467834091 GO:0004711 ribosomal protein S6 kinase activity 15/1416 245/18639 0.0612244897959184 0.805906260809409 0.841290651214647 0.973493467834091 GO:0035175 histone H3S10 kinase activity 15/1416 245/18639 0.0612244897959184 0.805906260809409 0.841290651214647 0.973493467834091 GO:0035979 histone H2AXS139 kinase activity 15/1416 245/18639 0.0612244897959184 0.805906260809409 0.841290651214647 0.973493467834091 GO:0044022 histone H3S28 kinase activity 15/1416 245/18639 0.0612244897959184 0.805906260809409 0.841290651214647 0.973493467834091 GO:0044023 histone H4S1 kinase activity 15/1416 245/18639 0.0612244897959184 0.805906260809409 0.841290651214647 0.973493467834091 GO:0044024 histone H2AS1 kinase activity 15/1416 245/18639 0.0612244897959184 0.805906260809409 0.841290651214647 0.973493467834091 GO:0044025 histone H2BS14 kinase activity 15/1416 245/18639 0.0612244897959184 0.805906260809409 0.841290651214647 0.973493467834091 GO:0072354 histone H3T3 kinase activity 15/1416 245/18639 0.0612244897959184 0.805906260809409 0.841290651214647 0.973493467834091 GO:0072371 histone H2AS121 kinase activity 15/1416 245/18639 0.0612244897959184 0.805906260809409 0.841290651214647 0.973493467834091 GO:0072518 Rho-dependent protein serine/threonine kinase activity 15/1416 245/18639 0.0612244897959184 0.805906260809409 0.841290651214647 0.973493467834091 GO:0140823 histone H2BS36 kinase activity 15/1416 245/18639 0.0612244897959184 0.805906260809409 0.841290651214647 0.973493467834091 GO:0140855 histone H3S57 kinase activity 15/1416 245/18639 0.0612244897959184 0.805906260809409 0.841290651214647 0.973493467834091 GO:0140995 histone H2A kinase activity 15/1416 245/18639 0.0612244897959184 0.805906260809409 0.841290651214647 0.973493467834091 GO:0140997 histone H4 kinase activity 15/1416 245/18639 0.0612244897959184 0.805906260809409 0.841290651214647 0.973493467834091 GO:0140998 histone H2B kinase activity 15/1416 245/18639 0.0612244897959184 0.805906260809409 0.841290651214647 0.973493467834091 GO:1990244 histone H2AT120 kinase activity 15/1416 245/18639 0.0612244897959184 0.805906260809409 0.841290651214647 0.973493467834091 GO:0004677 DNA-dependent protein kinase activity 15/1416 246/18639 0.0609756097560976 0.802630219098801 0.845524679214278 0.974680936735777 GO:0140857 histone H3T45 kinase activity 15/1416 246/18639 0.0609756097560976 0.802630219098801 0.845524679214278 0.974680936735777 GO:0035402 histone H3T11 kinase activity 15/1416 247/18639 0.0607287449392713 0.799380704041721 0.849672240160289 0.974680936735777 GO:0035403 histone H3T6 kinase activity 15/1416 247/18639 0.0607287449392713 0.799380704041721 0.849672240160289 0.974680936735777 GO:0004622 lysophospholipase activity 1/1416 24/18639 0.0416666666666667 0.548463983050847 0.850052421897428 0.974680936735777 GO:0015149 hexose transmembrane transporter activity 1/1416 24/18639 0.0416666666666667 0.548463983050847 0.850052421897428 0.974680936735777 GO:0055056 D-glucose transmembrane transporter activity 1/1416 24/18639 0.0416666666666667 0.548463983050847 0.850052421897428 0.974680936735777 GO:0070300 phosphatidic acid binding 1/1416 24/18639 0.0416666666666667 0.548463983050847 0.850052421897428 0.974680936735777 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 1/1416 24/18639 0.0416666666666667 0.548463983050847 0.850052421897428 0.974680936735777 GO:0019905 syntaxin binding 3/1416 61/18639 0.0491803278688525 0.647367324256738 0.852077223187026 0.976015728377867 GO:0004679 AMP-activated protein kinase activity 15/1416 248/18639 0.0604838709677419 0.79615739475123 0.853734089309181 0.976926798462777 GO:0016790 thiolester hydrolase activity 2/1416 44/18639 0.0454545454545455 0.598324345146379 0.857559361196945 0.977871910007161 GO:0004709 MAP kinase kinase kinase activity 1/1416 25/18639 0.04 0.526525423728814 0.861458587387261 0.977871910007161 GO:0015662 P-type ion transporter activity 1/1416 25/18639 0.04 0.526525423728814 0.861458587387261 0.977871910007161 GO:0017025 TBP-class protein binding 1/1416 25/18639 0.04 0.526525423728814 0.861458587387261 0.977871910007161 GO:0019706 protein-cysteine S-palmitoyltransferase activity 1/1416 25/18639 0.04 0.526525423728814 0.861458587387261 0.977871910007161 GO:0019707 protein-cysteine S-acyltransferase activity 1/1416 25/18639 0.04 0.526525423728814 0.861458587387261 0.977871910007161 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 1/1416 25/18639 0.04 0.526525423728814 0.861458587387261 0.977871910007161 GO:0140358 P-type transmembrane transporter activity 1/1416 25/18639 0.04 0.526525423728814 0.861458587387261 0.977871910007161 GO:0030246 carbohydrate binding 17/1416 280/18639 0.0607142857142857 0.799190375302663 0.862609928586287 0.978199659016849 GO:0022824 transmitter-gated monoatomic ion channel activity 3/1416 63/18639 0.0476190476190476 0.62681598062954 0.866900420853893 0.980997388208976 GO:0022835 transmitter-gated channel activity 3/1416 63/18639 0.0476190476190476 0.62681598062954 0.866900420853893 0.980997388208976 GO:0005227 calcium-activated cation channel activity 1/1416 26/18639 0.0384615384615385 0.50627444589309 0.871997678407979 0.980997388208976 GO:0008157 protein phosphatase 1 binding 1/1416 26/18639 0.0384615384615385 0.50627444589309 0.871997678407979 0.980997388208976 GO:0008198 ferrous iron binding 1/1416 26/18639 0.0384615384615385 0.50627444589309 0.871997678407979 0.980997388208976 GO:0015145 monosaccharide transmembrane transporter activity 1/1416 26/18639 0.0384615384615385 0.50627444589309 0.871997678407979 0.980997388208976 GO:0030247 polysaccharide binding 1/1416 26/18639 0.0384615384615385 0.50627444589309 0.871997678407979 0.980997388208976 GO:0051139 metal cation:proton antiporter activity 1/1416 26/18639 0.0384615384615385 0.50627444589309 0.871997678407979 0.980997388208976 GO:0140938 histone H3 methyltransferase activity 2/1416 47/18639 0.0425531914893617 0.560133429498738 0.88166716720429 0.988031749968518 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/1416 27/18639 0.037037037037037 0.487523540489642 0.881735565227637 0.988031749968518 GO:0008266 poly(U) RNA binding 1/1416 27/18639 0.037037037037037 0.487523540489642 0.881735565227637 0.988031749968518 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 1/1416 27/18639 0.037037037037037 0.487523540489642 0.881735565227637 0.988031749968518 GO:0008235 metalloexopeptidase activity 3/1416 66/18639 0.0454545454545455 0.598324345146379 0.886678913098649 0.992156515876334 GO:1990782 protein tyrosine kinase binding 6/1416 117/18639 0.0512820512820513 0.67503259452412 0.887734108836816 0.992156515876334 GO:0019787 ubiquitin-like protein transferase activity 30/1416 479/18639 0.0626304801670146 0.824413502706911 0.888041325938694 0.992156515876334 GO:0051119 sugar transmembrane transporter activity 1/1416 28/18639 0.0357142857142857 0.470111985472155 0.890733117325083 0.993206838787261 GO:0051959 dynein light intermediate chain binding 1/1416 28/18639 0.0357142857142857 0.470111985472155 0.890733117325083 0.993206838787261 GO:0016755 aminoacyltransferase activity 31/1416 496/18639 0.0625 0.822695974576271 0.893911345783125 0.99441922902653 GO:0015171 amino acid transmembrane transporter activity 5/1416 102/18639 0.0490196078431373 0.645251744765703 0.895092589045797 0.99441922902653 GO:0005548 phospholipid transporter activity 3/1416 68/18639 0.0441176470588235 0.580726570289133 0.89836265937587 0.99441922902653 GO:0030145 manganese ion binding 3/1416 68/18639 0.0441176470588235 0.580726570289133 0.89836265937587 0.99441922902653 GO:0032934 sterol binding 3/1416 68/18639 0.0441176470588235 0.580726570289133 0.89836265937587 0.99441922902653 GO:0004181 metallocarboxypeptidase activity 1/1416 29/18639 0.0344827586206897 0.453901227352425 0.899046582795379 0.99441922902653 GO:0005416 amino acid:monoatomic cation symporter activity 1/1416 29/18639 0.0344827586206897 0.453901227352425 0.899046582795379 0.99441922902653 GO:0099604 ligand-gated calcium channel activity 1/1416 29/18639 0.0344827586206897 0.453901227352425 0.899046582795379 0.99441922902653 GO:0016279 protein-lysine N-methyltransferase activity 3/1416 69/18639 0.0434782608695652 0.572310243183493 0.903787867887563 0.99441922902653 GO:0098960 postsynaptic neurotransmitter receptor activity 3/1416 69/18639 0.0434782608695652 0.572310243183493 0.903787867887563 0.99441922902653 GO:0008081 phosphoric diester hydrolase activity 4/1416 87/18639 0.0459770114942529 0.605201636469901 0.905002291040964 0.99441922902653 GO:0015108 chloride transmembrane transporter activity 6/1416 121/18639 0.0495867768595041 0.652717467432414 0.905241035680519 0.99441922902653 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 1/1416 30/18639 0.0333333333333333 0.438771186440678 0.906727938988917 0.99441922902653 GO:0008187 poly-pyrimidine tract binding 1/1416 30/18639 0.0333333333333333 0.438771186440678 0.906727938988917 0.99441922902653 GO:0022839 monoatomic ion-gated channel activity 1/1416 30/18639 0.0333333333333333 0.438771186440678 0.906727938988917 0.99441922902653 GO:0033612 receptor serine/threonine kinase binding 1/1416 30/18639 0.0333333333333333 0.438771186440678 0.906727938988917 0.99441922902653 GO:0048019 receptor antagonist activity 1/1416 30/18639 0.0333333333333333 0.438771186440678 0.906727938988917 0.99441922902653 GO:0016278 lysine N-methyltransferase activity 3/1416 70/18639 0.0428571428571429 0.564134382566586 0.908949893677854 0.99589292698617 GO:0070851 growth factor receptor binding 7/1416 139/18639 0.0503597122302158 0.662891720521888 0.910992415387178 0.997167373599479 GO:0047499 calcium-independent phospholipase A2 activity 1/1416 31/18639 0.032258064516129 0.424617277200656 0.913825216563838 0.999303563725547 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 2/1416 53/18639 0.0377358490566038 0.496722097857371 0.918950913352081 0.99999998440798 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/1416 32/18639 0.03125 0.411347987288136 0.920382798966332 0.99999998440798 GO:0047498 calcium-dependent phospholipase A2 activity 1/1416 32/18639 0.03125 0.411347987288136 0.920382798966332 0.99999998440798 GO:0020037 heme binding 7/1416 142/18639 0.0492957746478873 0.648886965862974 0.921338979095474 0.99999998440798 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 4/1416 91/18639 0.043956043956044 0.57859936673496 0.922316030388658 0.99999998440798 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 3/1416 73/18639 0.0410958904109589 0.540950777803576 0.922962122038224 0.99999998440798 GO:0140311 protein sequestering activity 1/1416 33/18639 0.0303030303030303 0.398882896764253 0.92644169920085 0.99999998440798 GO:0008083 growth factor activity 8/1416 162/18639 0.0493827160493827 0.650031387319523 0.931719204259992 0.99999998440798 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/1416 34/18639 0.0294117647058824 0.387151046859422 0.932039815611233 0.99999998440798 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 1/1416 34/18639 0.0294117647058824 0.387151046859422 0.932039815611233 0.99999998440798 GO:0035591 signaling adaptor activity 6/1416 129/18639 0.0465116279069767 0.612238864800946 0.933292918431733 0.99999998440798 GO:0004623 phospholipase A2 activity 1/1416 35/18639 0.0285714285714286 0.376089588377724 0.93721216826345 0.99999998440798 GO:0016229 steroid dehydrogenase activity 1/1416 35/18639 0.0285714285714286 0.376089588377724 0.93721216826345 0.99999998440798 GO:0043015 gamma-tubulin binding 1/1416 35/18639 0.0285714285714286 0.376089588377724 0.93721216826345 0.99999998440798 GO:0004190 aspartic-type endopeptidase activity 1/1416 36/18639 0.0277777777777778 0.365642655367232 0.941991117400139 0.99999998440798 GO:0004869 cysteine-type endopeptidase inhibitor activity 1/1416 36/18639 0.0277777777777778 0.365642655367232 0.941991117400139 0.99999998440798 GO:0045505 dynein intermediate chain binding 1/1416 36/18639 0.0277777777777778 0.365642655367232 0.941991117400139 0.99999998440798 GO:0061659 ubiquitin-like protein ligase activity 21/1416 372/18639 0.0564516129032258 0.743080235101148 0.942636352221608 0.99999998440798 GO:0030594 neurotransmitter receptor activity 4/1416 97/18639 0.0412371134020619 0.542809715184344 0.943001492035114 0.99999998440798 GO:0070888 E-box binding 2/1416 59/18639 0.0338983050847458 0.446207986210859 0.944966764923887 0.99999998440798 GO:0008170 N-methyltransferase activity 4/1416 98/18639 0.0408163265306122 0.537270840539606 0.945914618556854 0.99999998440798 GO:0019213 deacetylase activity 1/1416 37/18639 0.027027027027027 0.355760421438388 0.946406565325817 0.99999998440798 GO:0030551 cyclic nucleotide binding 1/1416 37/18639 0.027027027027027 0.355760421438388 0.946406565325817 0.99999998440798 GO:0070001 aspartic-type peptidase activity 1/1416 37/18639 0.027027027027027 0.355760421438388 0.946406565325817 0.99999998440798 GO:0005501 retinoid binding 1/1416 38/18639 0.0263157894736842 0.346398305084746 0.950486142978685 0.99999998440798 GO:0019840 isoprenoid binding 1/1416 38/18639 0.0263157894736842 0.346398305084746 0.950486142978685 0.99999998440798 GO:0005254 chloride channel activity 3/1416 83/18639 0.036144578313253 0.475775985297121 0.956584998482199 0.99999998440798 GO:0015144 carbohydrate transmembrane transporter activity 1/1416 40/18639 0.025 0.329078389830508 0.957737875822528 0.99999998440798 GO:0071855 neuropeptide receptor binding 1/1416 40/18639 0.025 0.329078389830508 0.957737875822528 0.99999998440798 GO:0001727 lipid kinase activity 1/1416 41/18639 0.024390243902439 0.32105208763952 0.96095542342376 0.99999998440798 GO:0004812 aminoacyl-tRNA ligase activity 1/1416 41/18639 0.024390243902439 0.32105208763952 0.96095542342376 0.99999998440798 GO:0008227 G protein-coupled amine receptor activity 1/1416 41/18639 0.024390243902439 0.32105208763952 0.96095542342376 0.99999998440798 GO:0016875 ligase activity, forming carbon-oxygen bonds 1/1416 41/18639 0.024390243902439 0.32105208763952 0.96095542342376 0.99999998440798 GO:0140828 metal cation:monoatomic cation antiporter activity 1/1416 41/18639 0.024390243902439 0.32105208763952 0.96095542342376 0.99999998440798 GO:0120013 lipid transfer activity 2/1416 65/18639 0.0307692307692308 0.405019556714472 0.962903315152606 0.99999998440798 GO:0140098 catalytic activity, acting on RNA 21/1416 387/18639 0.0542635658914729 0.714278675601104 0.963093799942265 0.99999998440798 GO:0004842 ubiquitin-protein transferase activity 25/1416 449/18639 0.0556792873051225 0.732914008531199 0.963284173016646 0.99999998440798 GO:0005245 voltage-gated calcium channel activity 1/1416 43/18639 0.0232558139534884 0.306119432400473 0.966674725489638 0.99999998440798 GO:0030547 signaling receptor inhibitor activity 1/1416 44/18639 0.0227272727272727 0.29916217257319 0.969212292101096 0.99999998440798 GO:0004620 phospholipase activity 4/1416 109/18639 0.036697247706422 0.483050847457627 0.970071407386056 0.99999998440798 GO:0042605 peptide antigen binding 1/1416 45/18639 0.0222222222222222 0.292514124293785 0.971556760742389 0.99999998440798 GO:0140303 intramembrane lipid transporter activity 1/1416 45/18639 0.0222222222222222 0.292514124293785 0.971556760742389 0.99999998440798 GO:0030695 GTPase regulator activity 27/1416 489/18639 0.0552147239263804 0.726798897785172 0.971754569247444 0.99999998440798 GO:0060589 nucleoside-triphosphatase regulator activity 27/1416 490/18639 0.0551020408163265 0.725315634728468 0.972547353036095 0.99999998440798 GO:0016298 lipase activity 5/1416 130/18639 0.0384615384615385 0.50627444589309 0.973171024616966 0.99999998440798 GO:0004180 carboxypeptidase activity 1/1416 46/18639 0.0217391304347826 0.286155121591746 0.973722815748777 0.99999998440798 GO:0043178 alcohol binding 3/1416 92/18639 0.0326086956521739 0.42923268238762 0.974568348384357 0.99999998440798 GO:0099095 ligand-gated monoatomic anion channel activity 1/1416 47/18639 0.0212765957446809 0.280066714749369 0.975724025499744 0.99999998440798 GO:0061630 ubiquitin protein ligase activity 18/1416 353/18639 0.0509915014164306 0.671208047246363 0.975945255129981 0.99999998440798 GO:0038187 pattern recognition receptor activity 1/1416 48/18639 0.0208333333333333 0.274231991525424 0.977572927172096 0.99999998440798 GO:0005506 iron ion binding 6/1416 154/18639 0.038961038961039 0.512849438696896 0.979624765676926 0.99999998440798 GO:0005272 sodium channel activity 1/1416 51/18639 0.0196078431372549 0.258100697906281 0.982317291016434 0.99999998440798 GO:0042626 ATPase-coupled transmembrane transporter activity 3/1416 98/18639 0.0306122448979592 0.402953130404704 0.982343988920082 0.99999998440798 GO:0001216 DNA-binding transcription activator activity 26/1416 491/18639 0.0529531568228106 0.697029583347717 0.98316322598657 0.99999998440798 GO:0030159 signaling receptor complex adaptor activity 1/1416 52/18639 0.0192307692307692 0.253137222946545 0.983664327594911 0.99999998440798 GO:0005319 lipid transporter activity 7/1416 178/18639 0.0393258426966292 0.517651399733384 0.984527784589201 0.99999998440798 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 4/1416 122/18639 0.0327868852459016 0.431578216171159 0.98557620261662 0.99999998440798 GO:0046873 metal ion transmembrane transporter activity 23/1416 450/18639 0.0511111111111111 0.672782485875706 0.986286248748771 0.99999998440798 GO:0030971 receptor tyrosine kinase binding 2/1416 81/18639 0.0246913580246914 0.325015693659761 0.987401659139116 0.99999998440798 GO:0000149 SNARE binding 3/1416 106/18639 0.0283018867924528 0.372541573393028 0.989244586281226 0.99999998440798 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 24/1416 484/18639 0.0495867768595041 0.652717467432414 0.992436071750255 0.99999998440798 GO:0008236 serine-type peptidase activity 7/1416 194/18639 0.0360824742268041 0.474958500786301 0.993004472054074 0.99999998440798 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 11/1416 268/18639 0.041044776119403 0.540277953453074 0.993223889004181 0.99999998440798 GO:0099094 ligand-gated monoatomic cation channel activity 4/1416 136/18639 0.0294117647058824 0.387151046859422 0.993628373626878 0.99999998440798 GO:0160215 deacylase activity 1/1416 65/18639 0.0153846153846154 0.202509778357236 0.994170807284898 0.99999998440798 GO:0017171 serine hydrolase activity 7/1416 198/18639 0.0353535353535354 0.465363379558295 0.994296376694929 0.99999998440798 GO:0140767 enzyme-substrate adaptor activity 4/1416 139/18639 0.0287769784172662 0.37879526886965 0.994671182380894 0.99999998440798 GO:0015079 potassium ion transmembrane transporter activity 5/1416 160/18639 0.03125 0.411347987288136 0.99472751275534 0.99999998440798 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 6/1416 181/18639 0.0331491712707182 0.436347036239348 0.994989546552433 0.99999998440798 GO:0008173 RNA methyltransferase activity 1/1416 67/18639 0.0149253731343284 0.196464710346572 0.995025734884886 0.99999998440798 GO:0004896 cytokine receptor activity 2/1416 96/18639 0.0208333333333333 0.274231991525424 0.995550877092737 0.99999998440798 GO:0001217 DNA-binding transcription repressor activity 11/1416 278/18639 0.039568345323741 0.520843494695769 0.995676872093896 0.99999998440798 GO:0001664 G protein-coupled receptor binding 12/1416 297/18639 0.0404040404040404 0.531843862352337 0.995870232802923 0.99999998440798 GO:0022836 gated channel activity 13/1416 318/18639 0.0408805031446541 0.538115606012152 0.996408585322025 0.99999998440798 GO:0022834 ligand-gated channel activity 6/1416 188/18639 0.0319148936170213 0.420100072124053 0.99657539159987 0.99999998440798 GO:0005267 potassium channel activity 3/1416 124/18639 0.0241935483870968 0.318462957900492 0.996585561233305 0.99999998440798 GO:0015085 calcium ion transmembrane transporter activity 4/1416 147/18639 0.0272108843537415 0.358180560359737 0.996710094401132 0.99999998440798 GO:0005085 guanyl-nucleotide exchange factor activity 8/1416 230/18639 0.0347826086956522 0.457848194546794 0.997035574139001 0.99999998440798 GO:0005244 voltage-gated monoatomic ion channel activity 5/1416 173/18639 0.0289017341040462 0.380437444890761 0.997497260540956 0.99999998440798 GO:0022832 voltage-gated channel activity 5/1416 175/18639 0.0285714285714286 0.376089588377724 0.997772395332434 0.99999998440798 GO:0005262 calcium channel activity 3/1416 131/18639 0.0229007633587786 0.301445853279855 0.99783677872319 0.99999998440798 GO:0005179 hormone activity 3/1416 132/18639 0.0227272727272727 0.29916217257319 0.997974161447932 0.99999998440798 GO:0140101 catalytic activity, acting on a tRNA 3/1416 139/18639 0.0215827338129496 0.284096451652238 0.998723688269183 0.99999998440798 GO:0015276 ligand-gated monoatomic ion channel activity 5/1416 186/18639 0.0268817204301075 0.353847731000547 0.998835356331464 0.99999998440798 GO:0022843 voltage-gated monoatomic cation channel activity 3/1416 143/18639 0.020979020979021 0.276149697759867 0.999021811566049 0.99999998440798 GO:0005126 cytokine receptor binding 9/1416 275/18639 0.0327272727272727 0.430793528505393 0.999205297214546 0.99999998440798 GO:0004252 serine-type endopeptidase activity 4/1416 176/18639 0.0227272727272727 0.29916217257319 0.99946038304249 0.99999998440798 GO:0005249 voltage-gated potassium channel activity 1/1416 98/18639 0.0102040816326531 0.134317710134901 0.999575274181978 0.99999998440798 GO:0030527 structural constituent of chromatin 1/1416 98/18639 0.0102040816326531 0.134317710134901 0.999575274181978 0.99999998440798 GO:0004497 monooxygenase activity 1/1416 106/18639 0.00943396226415094 0.124180524464343 0.999775077021457 0.99999998440798 GO:0005216 monoatomic ion channel activity 16/1416 448/18639 0.0357142857142857 0.470111985472155 0.999884691196109 0.99999998440798 GO:0005261 monoatomic cation channel activity 10/1416 341/18639 0.0293255131964809 0.386015706546051 0.999931420685961 0.99999998440798 GO:0005125 cytokine activity 5/1416 234/18639 0.0213675213675214 0.281263581051717 0.99993978670637 0.99999998440798 GO:0140375 immune receptor activity 2/1416 156/18639 0.0128205128205128 0.16875814863103 0.999941375442481 0.99999998440798 GO:0003823 antigen binding 2/1416 174/18639 0.0114942528735632 0.151300409117475 0.999984535888303 0.99999998440798 GO:0045182 translation regulator activity 7/1416 356/18639 0.0196629213483146 0.258825699866692 0.999999464800506 0.99999998440798 GO:0030371 translation repressor activity 4/1416 329/18639 0.0121580547112462 0.160038122713925 0.99999998440798 0.99999998440798