ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003712	transcription coregulator activity	198/3668	495/18639	0.4	2.03260632497274	4.15582027571285e-26	5.48983858421668e-23
GO:0003714	transcription corepressor activity	90/3668	204/18639	0.441176470588235	2.24184521136699	1.34707258613748e-15	8.89741443143804e-13
GO:0003713	transcription coactivator activity	97/3668	256/18639	0.37890625	1.92541810080425	8.35701614847656e-12	3.67987277737918e-09
GO:0140658	ATP-dependent chromatin remodeler activity	66/3668	158/18639	0.417721518987342	2.12265850392723	1.48396073038763e-10	4.90078031210514e-08
GO:0061775	cohesin loader activity	64/3668	153/18639	0.418300653594771	2.12560138559241	2.61490315964947e-10	6.9085741477939e-08
GO:0000510	H3-H4 histone complex chaperone activity	62/3668	151/18639	0.410596026490066	2.08645020113096	1.2105284173395e-09	1.77678671033943e-07
GO:0140584	chromatin extrusion motor activity	62/3668	151/18639	0.410596026490066	2.08645020113096	1.2105284173395e-09	1.77678671033943e-07
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	62/3668	151/18639	0.410596026490066	2.08645020113096	1.2105284173395e-09	1.77678671033943e-07
GO:0140849	ATP-dependent H2AZ histone chaperone activity	62/3668	151/18639	0.410596026490066	2.08645020113096	1.2105284173395e-09	1.77678671033943e-07
GO:0004386	helicase activity	63/3668	155/18639	0.406451612903226	2.06539029795617	1.45321960611215e-09	1.82198163354741e-07
GO:0015616	DNA translocase activity	62/3668	152/18639	0.407894736842105	2.07272355507088	1.65509308119371e-09	1.82198163354741e-07
GO:0140674	ATP-dependent histone chaperone activity	62/3668	152/18639	0.407894736842105	2.07272355507088	1.65509308119371e-09	1.82198163354741e-07
GO:0019787	ubiquitin-like protein transferase activity	148/3668	479/18639	0.308977035490605	1.57007169152383	2.19280750237954e-09	2.19801590388997e-07
GO:0003689	DNA clamp loader activity	64/3668	160/18639	0.4	2.03260632497274	2.32946424333532e-09	2.19801590388997e-07
GO:0030695	GTPase regulator activity	149/3668	489/18639	0.304703476482618	1.54835553384938	5.48292726756197e-09	4.82863128029958e-07
GO:0140597	protein carrier chaperone	71/3668	188/18639	0.377659574468085	1.91908309937586	5.92056984120578e-09	4.88817047514552e-07
GO:0060589	nucleoside-triphosphatase regulator activity	149/3668	490/18639	0.304081632653061	1.54519562459662	6.37312620669695e-09	4.9522939523804e-07
GO:0140097	catalytic activity, acting on DNA	110/3668	336/18639	0.327380952380952	1.66359148621281	8.23212503353439e-09	5.90190932900459e-07
GO:0016755	aminoacyltransferase activity	150/3668	496/18639	0.30241935483871	1.53674873359834	8.48874165413226e-09	5.90190932900459e-07
GO:0031267	small GTPase binding	96/3668	283/18639	0.339222614840989	1.72376508124896	1.00131725115423e-08	6.38494918013522e-07
GO:0140104	molecular carrier activity	87/3668	249/18639	0.349397590361446	1.77546938024727	1.01501841622134e-08	6.38494918013522e-07
GO:0008094	ATP-dependent activity, acting on DNA	76/3668	210/18639	0.361904761904762	1.83902477021343	1.54338978178045e-08	9.2673540987817e-07
GO:0140713	histone chaperone activity	63/3668	164/18639	0.384146341463415	1.95204570843418	1.96671574004952e-08	1.12871472747962e-06
GO:0004842	ubiquitin-protein transferase activity	137/3668	449/18639	0.305122494432071	1.55048478018522	2.05065506885017e-08	1.12871472747962e-06
GO:0016758	hexosyltransferase activity	72/3668	197/18639	0.365482233502538	1.85720374870605	2.29172817684962e-08	1.21094916864734e-06
GO:0140297	DNA-binding transcription factor binding	146/3668	488/18639	0.299180327868852	1.52028956683412	2.86319461766511e-08	1.45472311151369e-06
GO:0016887	ATP hydrolysis activity	128/3668	417/18639	0.306954436450839	1.55979382252105	4.05143368412905e-08	1.98220144323499e-06
GO:0045296	cadherin binding	107/3668	334/18639	0.320359281437126	1.62791075428206	4.7115279980095e-08	2.22283160191806e-06
GO:0140033	acetylation-dependent protein binding	17/3668	24/18639	0.708333333333333	3.59940703380589	8.00301875247472e-08	3.64551302483417e-06
GO:0051020	GTPase binding	101/3668	315/18639	0.320634920634921	1.62931141922418	1.05951263430455e-07	4.6183190541875e-06
GO:0016780	phosphotransferase activity, for other substituted phosphate groups	16/3668	22/18639	0.727272727272727	3.6956478635868	1.08378418379873e-07	4.6183190541875e-06
GO:0061659	ubiquitin-like protein ligase activity	115/3668	372/18639	0.309139784946237	1.57089870545608	1.29221156293263e-07	5.33441085823128e-06
GO:0070577	lysine-acetylated histone binding	16/3668	23/18639	0.695652173913043	3.53496752169172	2.90684546922591e-07	1.1335593195746e-05
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	108/3668	349/18639	0.30945558739255	1.57250346058063	2.91756372941229e-07	1.1335593195746e-05
GO:0016922	nuclear receptor binding	51/3668	137/18639	0.372262773722628	1.89165917105127	1.29455566306566e-06	4.88602294545638e-05
GO:0061630	ubiquitin protein ligase activity	106/3668	353/18639	0.30028328611898	1.52589426662259	1.82097955821974e-06	6.68198332335633e-05
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	28/3668	60/18639	0.466666666666667	2.37137404580153	2.07542990090544e-06	7.40984567323267e-05
GO:0043138	3'-5' DNA helicase activity	24/3668	48/18639	0.5	2.54075790621592	2.39284931669963e-06	8.31829986147423e-05
GO:0015923	mannosidase activity	12/3668	16/18639	0.75	3.81113685932388	2.72504625622252e-06	8.95636558548056e-05
GO:0042393	histone binding	79/3668	247/18639	0.319838056680162	1.62526214243772	2.75986873295171e-06	8.95636558548056e-05
GO:0016757	glycosyltransferase activity	84/3668	267/18639	0.314606741573034	1.59867913200103	2.84162840050583e-06	8.95636558548056e-05
GO:0005096	GTPase activator activity	85/3668	271/18639	0.313653136531365	1.59383337290298	2.84759541703394e-06	8.95636558548056e-05
GO:1990518	single-stranded 3'-5' DNA helicase activity	23/3668	47/18639	0.48936170212766	2.48669922736026	6.17647187334896e-06	0.000189746961504511
GO:0051787	misfolded protein binding	12/3668	17/18639	0.705882352941177	3.58695233818718	7.59540871714067e-06	0.00022803488443961
GO:0140857	histone H3T45 kinase activity	77/3668	246/18639	0.313008130081301	1.59055576242785	8.87997475974857e-06	0.00026067659239173
GO:0009378	four-way junction helicase activity	23/3668	48/18639	0.479166666666667	2.43489299345692	9.65740462546636e-06	0.000271434712983852
GO:0036121	double-stranded DNA helicase activity	23/3668	48/18639	0.479166666666667	2.43489299345692	9.65740462546636e-06	0.000271434712983852
GO:0004559	alpha-mannosidase activity	11/3668	15/18639	0.733333333333333	3.72644492911668	1.04756581059011e-05	0.000288298840789487
GO:0004679	AMP-activated protein kinase activity	77/3668	248/18639	0.310483870967742	1.57772869982763	1.22699718654654e-05	0.000288766072093036
GO:0004676	3-phosphoinositide-dependent protein kinase activity	76/3668	245/18639	0.310204081632653	1.57630694589722	1.44273737760336e-05	0.000288766072093036
GO:0004711	ribosomal protein S6 kinase activity	76/3668	245/18639	0.310204081632653	1.57630694589722	1.44273737760336e-05	0.000288766072093036
GO:0035175	histone H3S10 kinase activity	76/3668	245/18639	0.310204081632653	1.57630694589722	1.44273737760336e-05	0.000288766072093036
GO:0035979	histone H2AXS139 kinase activity	76/3668	245/18639	0.310204081632653	1.57630694589722	1.44273737760336e-05	0.000288766072093036
GO:0044022	histone H3S28 kinase activity	76/3668	245/18639	0.310204081632653	1.57630694589722	1.44273737760336e-05	0.000288766072093036
GO:0044023	histone H4S1 kinase activity	76/3668	245/18639	0.310204081632653	1.57630694589722	1.44273737760336e-05	0.000288766072093036
GO:0044024	histone H2AS1 kinase activity	76/3668	245/18639	0.310204081632653	1.57630694589722	1.44273737760336e-05	0.000288766072093036
GO:0044025	histone H2BS14 kinase activity	76/3668	245/18639	0.310204081632653	1.57630694589722	1.44273737760336e-05	0.000288766072093036
GO:0072354	histone H3T3 kinase activity	76/3668	245/18639	0.310204081632653	1.57630694589722	1.44273737760336e-05	0.000288766072093036
GO:0072371	histone H2AS121 kinase activity	76/3668	245/18639	0.310204081632653	1.57630694589722	1.44273737760336e-05	0.000288766072093036
GO:0072518	Rho-dependent protein serine/threonine kinase activity	76/3668	245/18639	0.310204081632653	1.57630694589722	1.44273737760336e-05	0.000288766072093036
GO:0140823	histone H2BS36 kinase activity	76/3668	245/18639	0.310204081632653	1.57630694589722	1.44273737760336e-05	0.000288766072093036
GO:0140855	histone H3S57 kinase activity	76/3668	245/18639	0.310204081632653	1.57630694589722	1.44273737760336e-05	0.000288766072093036
GO:0140995	histone H2A kinase activity	76/3668	245/18639	0.310204081632653	1.57630694589722	1.44273737760336e-05	0.000288766072093036
GO:0140997	histone H4 kinase activity	76/3668	245/18639	0.310204081632653	1.57630694589722	1.44273737760336e-05	0.000288766072093036
GO:0140998	histone H2B kinase activity	76/3668	245/18639	0.310204081632653	1.57630694589722	1.44273737760336e-05	0.000288766072093036
GO:1990244	histone H2AT120 kinase activity	76/3668	245/18639	0.310204081632653	1.57630694589722	1.44273737760336e-05	0.000288766072093036
GO:0140457	protein demethylase activity	17/3668	31/18639	0.548387096774194	2.78663770359166	1.47950006591832e-05	0.000291704415981805
GO:0004677	DNA-dependent protein kinase activity	76/3668	246/18639	0.308943089430894	1.56989919408463	1.69073874539023e-05	0.000325131631045657
GO:0004674	protein serine/threonine kinase activity	121/3668	433/18639	0.279445727482679	1.42000788291975	1.71552731132906e-05	0.000325131631045657
GO:0070063	RNA polymerase binding	26/3668	59/18639	0.440677966101695	2.23931205293607	1.72287768154398e-05	0.000325131631045657
GO:0070064	proline-rich region binding	12/3668	18/18639	0.666666666666667	3.3876772082879	1.86855830452805e-05	0.000347657115532613
GO:0035402	histone H3T11 kinase activity	76/3668	247/18639	0.307692307692308	1.56354332690211	1.97783766656476e-05	0.000354738479991064
GO:0035403	histone H3T6 kinase activity	76/3668	247/18639	0.307692307692308	1.56354332690211	1.97783766656476e-05	0.000354738479991064
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	75/3668	243/18639	0.308641975308642	1.56836907791106	1.98717997875388e-05	0.000354738479991064
GO:0052742	phosphatidylinositol kinase activity	15/3668	26/18639	0.576923076923077	2.93164373794145	2.09971667992382e-05	0.000369830097890583
GO:0061749	forked DNA-dependent helicase activity	22/3668	47/18639	0.468085106382979	2.37858186964895	2.39267466202953e-05	0.000415884635334344
GO:0003724	RNA helicase activity	31/3668	77/18639	0.402597402597403	2.04580506734269	2.552971444371e-05	0.000437983802339493
GO:0106310	protein serine kinase activity	103/3668	361/18639	0.285318559556787	1.44985077196809	2.82708161418288e-05	0.000478791642607126
GO:0032452	histone demethylase activity	16/3668	30/18639	0.533333333333333	2.71014176663032	4.18799557604135e-05	0.000700296475436788
GO:0140416	transcription regulator inhibitor activity	17/3668	33/18639	0.515151515151515	2.61775057004065	4.34410746860341e-05	0.000717320745753138
GO:0008186	ATP-dependent activity, acting on RNA	31/3668	79/18639	0.392405063291139	1.99401253399224	4.6096123312917e-05	0.000751765171560041
GO:0017056	structural constituent of nuclear pore	14/3668	25/18639	0.56	2.84564885496183	6.24913613676204e-05	0.00100672058983691
GO:0046966	nuclear thyroid hormone receptor binding	15/3668	28/18639	0.535714285714286	2.72224061380277	6.81085875913447e-05	0.00107838031329789
GO:0015924	mannosyl-oligosaccharide mannosidase activity	8/3668	10/18639	0.8	4.06521264994547	6.85722530787455e-05	0.00107838031329789
GO:0003678	DNA helicase activity	29/3668	74/18639	0.391891891891892	1.99140484541248	8.2321911277455e-05	0.00127937935055904
GO:0008194	UDP-glycosyltransferase activity	48/3668	145/18639	0.331034482758621	1.68215695859813	9.1023232119287e-05	0.00139815918173928
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	69/3668	229/18639	0.301310043668122	1.53111175134409	9.57395758565121e-05	0.00145370091616612
GO:0042809	nuclear vitamin D receptor binding	10/3668	15/18639	0.666666666666667	3.3876772082879	9.72892910185614e-05	0.00146044492540363
GO:0001727	lipid kinase activity	19/3668	41/18639	0.463414634146341	2.35484879112695	0.000100938407476146	0.00148287016989636
GO:0140030	modification-dependent protein binding	55/3668	173/18639	0.317919075144509	1.61551080742053	0.000101028247759782	0.00148287016989636
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	18/3668	38/18639	0.473684210526316	2.40703380588877	0.000107625091208569	0.00154535592920131
GO:0042162	telomeric DNA binding	18/3668	38/18639	0.473684210526316	2.40703380588877	0.000107625091208569	0.00154535592920131
GO:0010485	histone H4 acetyltransferase activity	17/3668	35/18639	0.485714285714286	2.46816482318118	0.000112830046217385	0.00160267194680824
GO:0010484	histone H3 acetyltransferase activity	15/3668	29/18639	0.517241379310345	2.62837024780957	0.000115466805579381	0.00162267712947194
GO:0017116	single-stranded DNA helicase activity	24/3668	58/18639	0.413793103448276	2.10269619824766	0.000122139696261421	0.00169448898031887
GO:0046332	SMAD binding	30/3668	79/18639	0.379746835443038	1.92968954902475	0.000123142272604551	0.00169448898031887
GO:0022804	active transmembrane transporter activity	122/3668	457/18639	0.266958424507659	1.35655345539756	0.000140670773160676	0.00191573290046652
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	9/3668	13/18639	0.692307692307692	3.51797248552974	0.000144627288720347	0.00194951682040387
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	33/3668	91/18639	0.362637362637363	1.84274749242034	0.000163261822316251	0.00217847340686634
GO:0043995	histone H4K5 acetyltransferase activity	15/3668	30/18639	0.5	2.54075790621592	0.00018905365539835	0.00244843018412961
GO:0043996	histone H4K8 acetyltransferase activity	15/3668	30/18639	0.5	2.54075790621592	0.00018905365539835	0.00244843018412961
GO:0043997	histone H4K12 acetyltransferase activity	15/3668	30/18639	0.5	2.54075790621592	0.00018905365539835	0.00244843018412961
GO:0035091	phosphatidylinositol binding	81/3668	284/18639	0.285211267605634	1.44930556622176	0.000194563741206596	0.00249532720518362
GO:0030276	clathrin binding	20/3668	46/18639	0.434782608695652	2.20935470105732	0.000198148397919858	0.00251686570819358
GO:0001618	virus receptor activity	30/3668	81/18639	0.37037037037037	1.88204289349328	0.000207180838328903	0.00258551511830365
GO:0140098	catalytic activity, acting on RNA	105/3668	387/18639	0.271317829457364	1.37870584058228	0.000207467526525501	0.00258551511830365
GO:0008375	acetylglucosaminyltransferase activity	19/3668	43/18639	0.441860465116279	2.24532094037686	0.000220235807195778	0.0027189859935105
GO:0001221	transcription coregulator binding	39/3668	115/18639	0.339130434782609	1.72329666682471	0.000226973800366078	0.00276247976054281
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	24/3668	60/18639	0.4	2.03260632497274	0.000227941176305198	0.00276247976054281
GO:0004532	RNA exonuclease activity	18/3668	40/18639	0.45	2.28668211559433	0.000242628655897446	0.00289422581510662
GO:0141003	histone H2AX kinase activity	97/3668	354/18639	0.274011299435028	1.39239275086409	0.00024319384214749	0.00289422581510662
GO:0003756	protein disulfide isomerase activity	11/3668	19/18639	0.578947368421053	2.94193020719738	0.000264331125520353	0.00306204713389291
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	11/3668	19/18639	0.578947368421053	2.94193020719738	0.000264331125520353	0.00306204713389291
GO:0140272	exogenous protein binding	30/3668	82/18639	0.365853658536585	1.8590911508897	0.000265880250146619	0.00306204713389291
GO:0008234	cysteine-type peptidase activity	57/3668	187/18639	0.304812834224599	1.54891123694447	0.000266567312942986	0.00306204713389291
GO:1990841	promoter-specific chromatin binding	26/3668	68/18639	0.382352941176471	1.94293251651806	0.000299637320709916	0.00341224914360172
GO:0036408	histone H3K14 acetyltransferase activity	14/3668	28/18639	0.5	2.54075790621592	0.000309319259451048	0.00346280289605792
GO:0141052	histone H3 demethylase activity	14/3668	28/18639	0.5	2.54075790621592	0.000309319259451048	0.00346280289605792
GO:0140996	histone H3 kinase activity	97/3668	357/18639	0.271708683473389	1.38069197144507	0.000335341903886887	0.00372257693306368
GO:0000175	3'-5'-RNA exonuclease activity	16/3668	35/18639	0.457142857142857	2.3229786571117	0.000428361938340143	0.00471555100456107
GO:0016798	hydrolase activity, acting on glycosyl bonds	42/3668	130/18639	0.323076923076923	1.64172049324721	0.000433902169067755	0.00473706417635128
GO:0051087	protein-folding chaperone binding	43/3668	134/18639	0.32089552238806	1.6306356711535	0.000438974673802151	0.00475316019748067
GO:0004197	cysteine-type endopeptidase activity	31/3668	88/18639	0.352272727272727	1.79007943392485	0.000456790162691226	0.00488112778678088
GO:0035173	histone kinase activity	97/3668	360/18639	0.269444444444444	1.36918620501636	0.00045818307763878	0.00488112778678088
GO:0004843	cysteine-type deubiquitinase activity	36/3668	108/18639	0.333333333333333	1.69383860414395	0.000561625407225686	0.00593432508418559
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	31/3668	89/18639	0.348314606741573	1.76996618185828	0.000570521790833891	0.00593432508418559
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	31/3668	89/18639	0.348314606741573	1.76996618185828	0.000570521790833891	0.00593432508418559
GO:0005085	guanyl-nucleotide exchange factor activity	66/3668	230/18639	0.28695652173913	1.45817410269783	0.000604232236819594	0.00623586550655222
GO:0019838	growth factor binding	43/3668	136/18639	0.316176470588235	1.60665573481301	0.000621654306879298	0.0063659328634694
GO:0140793	histone H2AXY142 phosphatase activity	31/3668	90/18639	0.344444444444444	1.75029989094875	0.000708445953265936	0.00719890080203309
GO:0045322	unmethylated CpG binding	7/3668	10/18639	0.7	3.55706106870229	0.000776822368781132	0.00783345304702195
GO:0008238	exopeptidase activity	34/3668	102/18639	0.333333333333333	1.69383860414395	0.000787886957507415	0.00788483841566133
GO:0032451	demethylase activity	17/3668	40/18639	0.425	2.15964422028353	0.000807516712141466	0.00802052313337501
GO:0043998	histone H2A acetyltransferase activity	12/3668	24/18639	0.5	2.54075790621592	0.000833579966379054	0.00821760548945321
GO:0008408	3'-5' exonuclease activity	22/3668	58/18639	0.379310344827586	1.92747151506035	0.000963975857661967	0.00943268228127006
GO:0002039	p53 binding	25/3668	69/18639	0.36231884057971	1.84112891754777	0.000983779104784544	0.00955567792220869
GO:0004527	exonuclease activity	29/3668	84/18639	0.345238095238095	1.75433284000623	0.00099396250021543	0.00958412016631083
GO:0101005	deubiquitinase activity	37/3668	115/18639	0.321739130434783	1.63492247878242	0.00100521645961968	0.00962239813882318
GO:0004518	nuclease activity	60/3668	209/18639	0.287081339712919	1.45880836720531	0.001028288683124	0.00977244136983313
GO:0016407	acetyltransferase activity	32/3668	96/18639	0.333333333333333	1.69383860414395	0.00110663140200504	0.0102393182237749
GO:0004535	poly(A)-specific ribonuclease activity	8/3668	13/18639	0.615384615384615	3.12708665380421	0.00110841976230114	0.0102393182237749
GO:0017154	semaphorin receptor activity	8/3668	13/18639	0.615384615384615	3.12708665380421	0.00110841976230114	0.0102393182237749
GO:0070123	transforming growth factor beta receptor activity, type III	8/3668	13/18639	0.615384615384615	3.12708665380421	0.00110841976230114	0.0102393182237749
GO:0019789	SUMO transferase activity	13/3668	28/18639	0.464285714285714	2.35927519862907	0.00123059663776528	0.0109647076835683
GO:0005024	transforming growth factor beta receptor activity	9/3668	16/18639	0.5625	2.85835264449291	0.00130050012241245	0.0109647076835683
GO:0034450	ubiquitin-ubiquitin ligase activity	9/3668	16/18639	0.5625	2.85835264449291	0.00130050012241245	0.0109647076835683
GO:0051213	dioxygenase activity	31/3668	93/18639	0.333333333333333	1.69383860414395	0.00131217312683314	0.0109647076835683
GO:0000030	mannosyltransferase activity	12/3668	25/18639	0.48	2.43912758996728	0.0013177791684849	0.0109647076835683
GO:0008139	nuclear localization sequence binding	12/3668	25/18639	0.48	2.43912758996728	0.0013177791684849	0.0109647076835683
GO:0046915	transition metal ion transmembrane transporter activity	18/3668	45/18639	0.4	2.03260632497274	0.00134254912556011	0.0109647076835683
GO:0140303	intramembrane lipid transporter activity	18/3668	45/18639	0.4	2.03260632497274	0.00134254912556011	0.0109647076835683
GO:0032931	histone H3K56 acetyltransferase activity	11/3668	22/18639	0.5	2.54075790621592	0.00137403023657447	0.0109647076835683
GO:0043992	histone H3K9 acetyltransferase activity	11/3668	22/18639	0.5	2.54075790621592	0.00137403023657447	0.0109647076835683
GO:0043993	histone H3K18 acetyltransferase activity	11/3668	22/18639	0.5	2.54075790621592	0.00137403023657447	0.0109647076835683
GO:0043994	histone H3K23 acetyltransferase activity	11/3668	22/18639	0.5	2.54075790621592	0.00137403023657447	0.0109647076835683
GO:0043999	histone H2AK5 acetyltransferase activity	11/3668	22/18639	0.5	2.54075790621592	0.00137403023657447	0.0109647076835683
GO:0044012	histone H2AK9 acetyltransferase activity	11/3668	22/18639	0.5	2.54075790621592	0.00137403023657447	0.0109647076835683
GO:0044014	histone H2BK5 acetyltransferase activity	11/3668	22/18639	0.5	2.54075790621592	0.00137403023657447	0.0109647076835683
GO:0044015	histone H2BK12 acetyltransferase activity	11/3668	22/18639	0.5	2.54075790621592	0.00137403023657447	0.0109647076835683
GO:0044016	histone H3K4 acetyltransferase activity	11/3668	22/18639	0.5	2.54075790621592	0.00137403023657447	0.0109647076835683
GO:0044017	histone H3K27 acetyltransferase activity	11/3668	22/18639	0.5	2.54075790621592	0.00137403023657447	0.0109647076835683
GO:0044018	histone H3K36 acetyltransferase activity	11/3668	22/18639	0.5	2.54075790621592	0.00137403023657447	0.0109647076835683
GO:0046972	histone H4K16 acetyltransferase activity	11/3668	22/18639	0.5	2.54075790621592	0.00137403023657447	0.0109647076835683
GO:0050321	tau-protein kinase activity	11/3668	22/18639	0.5	2.54075790621592	0.00137403023657447	0.0109647076835683
GO:0140908	histone H3K122 acetyltransferase activity	11/3668	22/18639	0.5	2.54075790621592	0.00137403023657447	0.0109647076835683
GO:0046527	glucosyltransferase activity	10/3668	19/18639	0.526315789473684	2.67448200654308	0.00137785123048625	0.0109647076835683
GO:0015399	primary active transmembrane transporter activity	49/3668	166/18639	0.295180722891566	1.49996551089856	0.00149415857821269	0.011819062765383
GO:0004402	histone acetyltransferase activity	17/3668	42/18639	0.404761904761905	2.05680401931765	0.00155296277630993	0.0122110942113418
GO:0004725	protein tyrosine phosphatase activity	32/3668	98/18639	0.326530612244898	1.6592704693655	0.00162563913862386	0.0127066772022716
GO:0008378	galactosyltransferase activity	14/3668	32/18639	0.4375	2.22316316793893	0.00164484617834098	0.0127066772022716
GO:0140142	nucleocytoplasmic carrier activity	14/3668	32/18639	0.4375	2.22316316793893	0.00164484617834098	0.0127066772022716
GO:0016791	phosphatase activity	74/3668	273/18639	0.271062271062271	1.37740721655662	0.00170334195109415	0.0130820623104382
GO:0034212	protein N-acetyltransferase activity	20/3668	53/18639	0.377358490566038	1.91755313676673	0.00173586103926046	0.0131785772003625
GO:0051018	protein kinase A binding	20/3668	53/18639	0.377358490566038	1.91755313676673	0.00173586103926046	0.0131785772003625
GO:0002162	dystroglycan binding	7/3668	11/18639	0.636363636363636	3.23369188063845	0.00177268384984337	0.0133812306608177
GO:0043236	laminin binding	13/3668	29/18639	0.448275862068966	2.27792088143496	0.00183212973012626	0.013751382803959
GO:0044389	ubiquitin-like protein ligase binding	85/3668	322/18639	0.263975155279503	1.34139392564195	0.00190016848556699	0.0141814834431299
GO:0005518	collagen binding	25/3668	72/18639	0.347222222222222	1.76441521264995	0.00196420220006319	0.0145770286869858
GO:0034237	protein kinase A regulatory subunit binding	12/3668	26/18639	0.461538461538462	2.34531499035316	0.00201259525018793	0.0147702129194347
GO:0050750	low-density lipoprotein particle receptor binding	12/3668	26/18639	0.461538461538462	2.34531499035316	0.00201259525018793	0.0147702129194347
GO:0140034	methylation-dependent protein binding	26/3668	76/18639	0.342105263157895	1.738413304253	0.00205279138910855	0.0149131155803586
GO:0016409	palmitoyltransferase activity	15/3668	36/18639	0.416666666666667	2.11729825517993	0.00205464574990557	0.0149131155803586
GO:0048156	tau protein binding	17/3668	43/18639	0.395348837209302	2.00897136770561	0.00210324215110748	0.0151824201181037
GO:0044013	histone H2B acetyltransferase activity	11/3668	23/18639	0.478260869565217	2.43029017116306	0.00216861991161654	0.0154851183959214
GO:0140103	catalytic activity, acting on a glycoprotein	11/3668	23/18639	0.478260869565217	2.43029017116306	0.00216861991161654	0.0154851183959214
GO:0140463	chromatin-protein adaptor activity	20/3668	54/18639	0.37037037037037	1.88204289349328	0.00225407677915671	0.0158732320360208
GO:0002020	protease binding	41/3668	136/18639	0.301470588235294	1.53192756110078	0.00226489786617203	0.0158732320360208
GO:0140789	histone phosphatase activity	41/3668	136/18639	0.301470588235294	1.53192756110078	0.00226489786617203	0.0158732320360208
GO:0008484	sulfuric ester hydrolase activity	9/3668	17/18639	0.529411764705882	2.69021425364039	0.00228305381290231	0.0158732320360208
GO:0038191	neuropilin binding	9/3668	17/18639	0.529411764705882	2.69021425364039	0.00228305381290231	0.0158732320360208
GO:0008080	N-acetyltransferase activity	24/3668	69/18639	0.347826086956522	1.76748376084586	0.00233104495673672	0.0161220439154409
GO:0005178	integrin binding	47/3668	161/18639	0.291925465838509	1.48342387070992	0.00235520220037034	0.016204281805673
GO:0061733	protein-lysine-acetyltransferase activity	18/3668	47/18639	0.382978723404255	1.94611243880368	0.00239421763537116	0.0163028943109552
GO:0140938	histone H3 methyltransferase activity	18/3668	47/18639	0.382978723404255	1.94611243880368	0.00239421763537116	0.0163028943109552
GO:0004540	RNA nuclease activity	37/3668	121/18639	0.305785123966942	1.55385194264445	0.00275603850710171	0.0186703941942634
GO:0004721	phosphoprotein phosphatase activity	50/3668	175/18639	0.285714285714286	1.45186166069481	0.00285494758598897	0.0192417640872012
GO:0035064	methylated histone binding	25/3668	74/18639	0.337837837837838	1.71672831501076	0.00300455892424235	0.0201473215173815
GO:0019199	transmembrane receptor protein kinase activity	26/3668	78/18639	0.333333333333333	1.69383860414395	0.003094412560783	0.0206450454181532
GO:0030215	semaphorin receptor binding	11/3668	24/18639	0.458333333333333	2.32902808069793	0.00329826909604828	0.0217698525245646
GO:0042626	ATPase-coupled transmembrane transporter activity	31/3668	98/18639	0.316326530612245	1.60741826719783	0.00331060713645395	0.0217698525245646
GO:0008013	beta-catenin binding	33/3668	106/18639	0.311320754716981	1.58198133783255	0.00331244538791633	0.0217698525245646
GO:0050840	extracellular matrix binding	23/3668	67/18639	0.343283582089552	1.7444009505363	0.00344242974560045	0.022118910756103
GO:0031625	ubiquitin protein ligase binding	79/3668	302/18639	0.26158940397351	1.32927069265601	0.00347005746277031	0.022118910756103
GO:0003995	acyl-CoA dehydrogenase activity	7/3668	12/18639	0.583333333333333	2.96421755725191	0.00353299785733363	0.022118910756103
GO:0005025	transforming growth factor beta receptor activity, type I	7/3668	12/18639	0.583333333333333	2.96421755725191	0.00353299785733363	0.022118910756103
GO:0005026	transforming growth factor beta receptor activity, type II	7/3668	12/18639	0.583333333333333	2.96421755725191	0.00353299785733363	0.022118910756103
GO:0005049	nuclear export signal receptor activity	7/3668	12/18639	0.583333333333333	2.96421755725191	0.00353299785733363	0.022118910756103
GO:0016361	activin receptor activity, type I	7/3668	12/18639	0.583333333333333	2.96421755725191	0.00353299785733363	0.022118910756103
GO:0016362	activin receptor activity, type II	7/3668	12/18639	0.583333333333333	2.96421755725191	0.00353299785733363	0.022118910756103
GO:0017002	activin receptor activity	7/3668	12/18639	0.583333333333333	2.96421755725191	0.00353299785733363	0.022118910756103
GO:0052890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	7/3668	12/18639	0.583333333333333	2.96421755725191	0.00353299785733363	0.022118910756103
GO:0140312	cargo adaptor activity	10/3668	21/18639	0.476190476190476	2.41976943449135	0.00357983708287773	0.0223064376720825
GO:0019783	ubiquitin-like protein peptidase activity	38/3668	127/18639	0.299212598425197	1.52045355017646	0.00369425386807536	0.0228709917558415
GO:0070325	lipoprotein particle receptor binding	13/3668	31/18639	0.419354838709677	2.13095824392303	0.00376115339349844	0.0228709917558415
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	9/3668	18/18639	0.5	2.54075790621592	0.00377431960845833	0.0228709917558415
GO:0030228	lipoprotein particle receptor activity	9/3668	18/18639	0.5	2.54075790621592	0.00377431960845833	0.0228709917558415
GO:0035615	clathrin adaptor activity	9/3668	18/18639	0.5	2.54075790621592	0.00377431960845833	0.0228709917558415
GO:0052744	phosphatidylinositol monophosphate phosphatase activity	9/3668	18/18639	0.5	2.54075790621592	0.00377431960845833	0.0228709917558415
GO:0043175	RNA polymerase core enzyme binding	16/3668	42/18639	0.380952380952381	1.93581554759308	0.00435513844255037	0.0262700359936486
GO:0032182	ubiquitin-like protein binding	36/3668	120/18639	0.3	1.52445474372955	0.00441580755662331	0.02651491719227
GO:0051117	ATPase binding	27/3668	84/18639	0.321428571428571	1.63334436828166	0.00460460763300317	0.0275234691547384
GO:0043130	ubiquitin binding	31/3668	100/18639	0.31	1.57526990185387	0.00464021273515281	0.027611355960076
GO:0038024	cargo receptor activity	22/3668	65/18639	0.338461538461538	1.71989765959232	0.00505936246073305	0.0299704834557326
GO:0003697	single-stranded DNA binding	36/3668	121/18639	0.297520661157025	1.5118559441946	0.00511876856583245	0.0301870235511815
GO:0008239	dipeptidyl-peptidase activity	6/3668	10/18639	0.6	3.04890948745911	0.00584288013249176	0.0341524099779717
GO:0016303	1-phosphatidylinositol-3-kinase activity	6/3668	10/18639	0.6	3.04890948745911	0.00584288013249176	0.0341524099779717
GO:1990380	K48-linked deubiquitinase activity	9/3668	19/18639	0.473684210526316	2.40703380588877	0.00593114114863319	0.0345155835125306
GO:0000993	RNA polymerase II complex binding	14/3668	36/18639	0.388888888888889	1.97614503816794	0.00602538354301839	0.0347821700941117
GO:0035250	UDP-galactosyltransferase activity	12/3668	29/18639	0.413793103448276	2.10269619824766	0.00602961162115941	0.0347821700941117
GO:0051011	microtubule minus-end binding	7/3668	13/18639	0.538461538461538	2.73620082207868	0.00636167230153818	0.0365381265666606
GO:0016410	N-acyltransferase activity	29/3668	94/18639	0.308510638297872	1.56770168681408	0.00650714747423127	0.0372118693223355
GO:0042578	phosphoric ester hydrolase activity	91/3668	363/18639	0.25068870523416	1.27387861964545	0.0065790112315283	0.0374606630898659
GO:0004177	aminopeptidase activity	15/3668	40/18639	0.375	1.90556842966194	0.00673409398066002	0.0380159749933841
GO:0030331	nuclear estrogen receptor binding	15/3668	40/18639	0.375	1.90556842966194	0.00673409398066002	0.0380159749933841
GO:0050681	nuclear androgen receptor binding	11/3668	26/18639	0.423076923076923	2.14987207449039	0.00693833524626551	0.038837037543715
GO:0070006	metalloaminopeptidase activity	11/3668	26/18639	0.423076923076923	2.14987207449039	0.00693833524626551	0.038837037543715
GO:0071889	14-3-3 protein binding	13/3668	33/18639	0.393939393939394	2.00180925944285	0.00707086026269357	0.0394118413798236
GO:0031490	chromatin DNA binding	37/3668	128/18639	0.2890625	1.46887566453108	0.00763158005792536	0.0423584758677286
GO:0030165	PDZ domain binding	26/3668	83/18639	0.313253012048193	1.59180013401479	0.00777940252226366	0.0429982875812146
GO:0005158	insulin receptor binding	10/3668	23/18639	0.434782608695652	2.20935470105732	0.00791753987262832	0.043579459048925
GO:0140318	protein transporter activity	15/3668	41/18639	0.365853658536585	1.8590911508897	0.00872243111335853	0.0478105041524756
GO:0030145	manganese ion binding	22/3668	68/18639	0.323529411764706	1.64401982166913	0.00913707085985829	0.0496710724521514
GO:0032934	sterol binding	22/3668	68/18639	0.323529411764706	1.64401982166913	0.00913707085985829	0.0496710724521514
GO:0090482	vitamin transmembrane transporter activity	13/3668	34/18639	0.382352941176471	1.94293251651806	0.00942170121343515	0.0510084725530649
GO:0005385	zinc ion transmembrane transporter activity	11/3668	27/18639	0.407407407407407	2.0702471828426	0.00965942749763115	0.0518703403429705
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	11/3668	27/18639	0.407407407407407	2.0702471828426	0.00965942749763115	0.0518703403429705
GO:0004438	phosphatidylinositol-3-phosphate phosphatase activity	8/3668	17/18639	0.470588235294118	2.39130155879146	0.00987058158471764	0.0526969226692726
GO:0043021	ribonucleoprotein complex binding	48/3668	177/18639	0.271186440677966	1.37803818642219	0.00989313915365602	0.0526969226692726
GO:1901505	carbohydrate derivative transmembrane transporter activity	18/3668	53/18639	0.339622641509434	1.72579782309006	0.0102391616422717	0.0543210141744613
GO:0015932	nucleobase-containing compound transmembrane transporter activity	19/3668	57/18639	0.333333333333333	1.69383860414395	0.0105374571646052	0.0550367149093245
GO:0005545	1-phosphatidylinositol binding	7/3668	14/18639	0.5	2.54075790621592	0.0105823812164787	0.0550367149093245
GO:0042813	Wnt receptor activity	7/3668	14/18639	0.5	2.54075790621592	0.0105823812164787	0.0550367149093245
GO:0061665	SUMO ligase activity	7/3668	14/18639	0.5	2.54075790621592	0.0105823812164787	0.0550367149093245
GO:0098821	BMP receptor activity	7/3668	14/18639	0.5	2.54075790621592	0.0105823812164787	0.0550367149093245
GO:0032050	clathrin heavy chain binding	6/3668	11/18639	0.545454545454545	2.7717358976901	0.0107271156716699	0.0551382093473769
GO:0048185	activin binding	6/3668	11/18639	0.545454545454545	2.7717358976901	0.0107271156716699	0.0551382093473769
GO:0097493	structural molecule activity conferring elasticity	6/3668	11/18639	0.545454545454545	2.7717358976901	0.0107271156716699	0.0551382093473769
GO:0005319	lipid transporter activity	48/3668	178/18639	0.269662921348315	1.37029639885803	0.011018243204982	0.0564151134642682
GO:0035035	histone acetyltransferase binding	10/3668	24/18639	0.416666666666667	2.11729825517993	0.0112170189987569	0.0572111277890266
GO:0004713	protein tyrosine kinase activity	39/3668	140/18639	0.278571428571429	1.41556511917744	0.0119802640750609	0.0608689570890593
GO:0140566	histone reader activity	13/3668	35/18639	0.371428571428571	1.88742015890326	0.0123410837236644	0.0624619601492746
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	18/3668	54/18639	0.333333333333333	1.69383860414395	0.0125952800853829	0.063263745219737
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	18/3668	54/18639	0.333333333333333	1.69383860414395	0.0125952800853829	0.063263745219737
GO:0051010	microtubule plus-end binding	9/3668	21/18639	0.428571428571429	2.17779249104222	0.0129329645003128	0.0647138110034593
GO:0045499	chemorepellent activity	11/3668	28/18639	0.392857142857143	1.99630978345537	0.013132001278992	0.0654617875077297
GO:0005543	phospholipid binding	118/3668	497/18639	0.237424547283702	1.2064765912816	0.0134854011359414	0.0669707327089421
GO:0015291	secondary active transmembrane transporter activity	72/3668	287/18639	0.250871080139373	1.27480536061008	0.0140682430565902	0.0696035545983358
GO:0019842	vitamin binding	41/3668	150/18639	0.273333333333333	1.38894765539804	0.0141376534050934	0.0696859707019715
GO:1901981	phosphatidylinositol phosphate binding	49/3668	185/18639	0.264864864864865	1.34591499896843	0.0144809124988235	0.0711125851708023
GO:0043495	protein-membrane adaptor activity	16/3668	47/18639	0.340425531914894	1.72987772338105	0.0146509512118401	0.0715787207816087
GO:0070717	poly-purine tract binding	12/3668	32/18639	0.375	1.90556842966194	0.0146842038847963	0.0715787207816087
GO:1990381	ubiquitin-specific protease binding	8/3668	18/18639	0.444444444444444	2.25845147219193	0.0147475911657251	0.0716234115070693
GO:0005048	signal sequence binding	17/3668	51/18639	0.333333333333333	1.69383860414395	0.0150716611082534	0.0729291733479953
GO:0003725	double-stranded RNA binding	23/3668	75/18639	0.306666666666667	1.55833151581243	0.0154118979990563	0.0739893349909915
GO:0019706	protein-cysteine S-palmitoyltransferase activity	10/3668	25/18639	0.4	2.03260632497274	0.0154587861146962	0.0739893349909915
GO:0019707	protein-cysteine S-acyltransferase activity	10/3668	25/18639	0.4	2.03260632497274	0.0154587861146962	0.0739893349909915
GO:0005041	low-density lipoprotein particle receptor activity	7/3668	15/18639	0.466666666666667	2.37137404580153	0.0165167546046961	0.0779236886885839
GO:0015929	hexosaminidase activity	7/3668	15/18639	0.466666666666667	2.37137404580153	0.0165167546046961	0.0779236886885839
GO:0048531	beta-1,3-galactosyltransferase activity	7/3668	15/18639	0.466666666666667	2.37137404580153	0.0165167546046961	0.0779236886885839
GO:0061578	K63-linked deubiquitinase activity	7/3668	15/18639	0.466666666666667	2.37137404580153	0.0165167546046961	0.0779236886885839
GO:0016417	S-acyltransferase activity	11/3668	29/18639	0.379310344827586	1.92747151506035	0.0174723505143341	0.0818474291823946
GO:0051861	glycolipid binding	11/3668	29/18639	0.379310344827586	1.92747151506035	0.0174723505143341	0.0818474291823946
GO:0000995	RNA polymerase III general transcription initiation factor activity	6/3668	12/18639	0.5	2.54075790621592	0.0179212334860061	0.0822012133160209
GO:0005165	neurotrophin receptor binding	6/3668	12/18639	0.5	2.54075790621592	0.0179212334860061	0.0822012133160209
GO:0017166	vinculin binding	6/3668	12/18639	0.5	2.54075790621592	0.0179212334860061	0.0822012133160209
GO:0045295	gamma-catenin binding	6/3668	12/18639	0.5	2.54075790621592	0.0179212334860061	0.0822012133160209
GO:0070008	serine-type exopeptidase activity	6/3668	12/18639	0.5	2.54075790621592	0.0179212334860061	0.0822012133160209
GO:1990247	N6-methyladenosine-containing RNA reader activity	6/3668	12/18639	0.5	2.54075790621592	0.0179212334860061	0.0822012133160209
GO:0032266	phosphatidylinositol-3-phosphate binding	16/3668	48/18639	0.333333333333333	1.69383860414395	0.0180572638615458	0.0825385659553702
GO:0008093	cytoskeletal anchor activity	9/3668	22/18639	0.409090909090909	2.07880192326757	0.0181356256856699	0.0826109018302411
GO:0022853	active monoatomic ion transmembrane transporter activity	33/3668	118/18639	0.279661016949153	1.42110187974789	0.0185123492379216	0.0840371592553073
GO:0008143	poly(A) binding	10/3668	26/18639	0.384615384615385	1.95442915862763	0.0207840679074653	0.0937056440469681
GO:0070412	R-SMAD binding	10/3668	26/18639	0.384615384615385	1.95442915862763	0.0207840679074653	0.0937056440469681
GO:0005520	insulin-like growth factor binding	8/3668	19/18639	0.421052631578947	2.13958560523446	0.0211595548145192	0.0947517691863723
GO:0042800	histone H3K4 methyltransferase activity	8/3668	19/18639	0.421052631578947	2.13958560523446	0.0211595548145192	0.0947517691863723
GO:0043539	protein serine/threonine kinase activator activity	22/3668	73/18639	0.301369863013699	1.53141572429453	0.0214774502331901	0.0958503775609599
GO:0031624	ubiquitin conjugating enzyme binding	11/3668	30/18639	0.366666666666667	1.86322246455834	0.0227952839156351	0.101389124756074
GO:0019902	phosphatase binding	49/3668	190/18639	0.257894736842105	1.31049618320611	0.0233902658418008	0.103686379788654
GO:0052866	phosphatidylinositol phosphate phosphatase activity	12/3668	34/18639	0.352941176470588	1.79347616909359	0.0242781321770063	0.107005963087788
GO:0005324	long-chain fatty acid transmembrane transporter activity	7/3668	16/18639	0.4375	2.22316316793893	0.0244631346347555	0.107005963087788
GO:0005521	lamin binding	7/3668	16/18639	0.4375	2.22316316793893	0.0244631346347555	0.107005963087788
GO:0140327	flippase activity	7/3668	16/18639	0.4375	2.22316316793893	0.0244631346347555	0.107005963087788
GO:0042887	amide transmembrane transporter activity	13/3668	38/18639	0.342105263157895	1.738413304253	0.0253300373101833	0.110094348393551
GO:0008276	protein methyltransferase activity	27/3668	95/18639	0.284210526315789	1.44422028353326	0.0253358682147157	0.110094348393551
GO:0048487	beta-tubulin binding	14/3668	42/18639	0.333333333333333	1.69383860414395	0.02603303743945	0.112752926090208
GO:0015605	organophosphate ester transmembrane transporter activity	16/3668	50/18639	0.32	1.62608505997819	0.026649251616902	0.115044645052051
GO:0016405	CoA-ligase activity	10/3668	27/18639	0.37037037037037	1.88204289349328	0.0273279740308971	0.117590402914707
GO:0005338	nucleotide-sugar transmembrane transporter activity	6/3668	13/18639	0.461538461538462	2.34531499035316	0.0278294287869785	0.118207959574272
GO:0031994	insulin-like growth factor I binding	6/3668	13/18639	0.461538461538462	2.34531499035316	0.0278294287869785	0.118207959574272
GO:0052650	all-trans-retinol dehydrogenase (NADP+) activity	6/3668	13/18639	0.461538461538462	2.34531499035316	0.0278294287869785	0.118207959574272
GO:0097157	pre-mRNA intronic binding	6/3668	13/18639	0.461538461538462	2.34531499035316	0.0278294287869785	0.118207959574272
GO:0016878	acid-thiol ligase activity	11/3668	31/18639	0.354838709677419	1.80311851408872	0.0292106071637613	0.123676961741438
GO:0015297	antiporter activity	36/3668	135/18639	0.266666666666667	1.35507088331516	0.0293588917622526	0.123907655009379
GO:0000182	rDNA binding	5/3668	10/18639	0.5	2.54075790621592	0.0306827446859585	0.12745882305079
GO:0034596	phosphatidylinositol phosphate 4-phosphatase activity	5/3668	10/18639	0.5	2.54075790621592	0.0306827446859585	0.12745882305079
GO:0042975	peroxisome proliferator activated receptor binding	5/3668	10/18639	0.5	2.54075790621592	0.0306827446859585	0.12745882305079
GO:0140999	histone H3K4 trimethyltransferase activity	5/3668	10/18639	0.5	2.54075790621592	0.0306827446859585	0.12745882305079
GO:1905394	retromer complex binding	5/3668	10/18639	0.5	2.54075790621592	0.0306827446859585	0.12745882305079
GO:0008374	O-acyltransferase activity	17/3668	55/18639	0.309090909090909	1.57065034202439	0.0317182998965446	0.130529203001045
GO:0098632	cell-cell adhesion mediator activity	17/3668	55/18639	0.309090909090909	1.57065034202439	0.0317182998965446	0.130529203001045
GO:0140313	molecular sequestering activity	17/3668	55/18639	0.309090909090909	1.57065034202439	0.0317182998965446	0.130529203001045
GO:0042625	ATPase-coupled ion transmembrane transporter activity	9/3668	24/18639	0.375	1.90556842966194	0.0327968208198033	0.132897546941596
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	9/3668	24/18639	0.375	1.90556842966194	0.0327968208198033	0.132897546941596
GO:0046961	proton-transporting ATPase activity, rotational mechanism	9/3668	24/18639	0.375	1.90556842966194	0.0327968208198033	0.132897546941596
GO:0050431	transforming growth factor beta binding	9/3668	24/18639	0.375	1.90556842966194	0.0327968208198033	0.132897546941596
GO:0070840	dynein complex binding	9/3668	24/18639	0.375	1.90556842966194	0.0327968208198033	0.132897546941596
GO:0098631	cell adhesion mediator activity	22/3668	76/18639	0.289473684210526	1.47096510359869	0.0334953674664871	0.135313089979295
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	7/3668	17/18639	0.411764705882353	2.09238886394252	0.034677921769782	0.139238707166815
GO:0019198	transmembrane receptor protein phosphatase activity	7/3668	17/18639	0.411764705882353	2.09238886394252	0.034677921769782	0.139238707166815
GO:0017124	SH3 domain binding	31/3668	115/18639	0.269565217391304	1.36979991465554	0.0356436932723682	0.142682784281207
GO:0042910	xenobiotic transmembrane transporter activity	11/3668	32/18639	0.34375	1.74677106052345	0.036819675547981	0.146944989120492
GO:0015101	organic cation transmembrane transporter activity	23/3668	81/18639	0.283950617283951	1.44289955167818	0.0372794037255744	0.148331603377963
GO:0044390	ubiquitin-like protein conjugating enzyme binding	12/3668	36/18639	0.333333333333333	1.69383860414395	0.0378038225335011	0.14996651521548
GO:0015036	disulfide oxidoreductase activity	13/3668	40/18639	0.325	1.65149263904035	0.0383125414958855	0.151529542862469
GO:0001223	transcription coactivator binding	14/3668	44/18639	0.318181818181818	1.61684594031922	0.0384562649653621	0.151643958266398
GO:0005123	death receptor binding	8/3668	21/18639	0.380952380952381	1.93581554759308	0.0393983049235307	0.154896311916619
GO:0004065	arylsulfatase activity	6/3668	14/18639	0.428571428571429	2.17779249104222	0.0407647144648534	0.158850111528234
GO:0005161	platelet-derived growth factor receptor binding	6/3668	14/18639	0.428571428571429	2.17779249104222	0.0407647144648534	0.158850111528234
GO:0032454	histone H3K9 demethylase activity	6/3668	14/18639	0.428571428571429	2.17779249104222	0.0407647144648534	0.158850111528234
GO:0050660	flavin adenine dinucleotide binding	24/3668	86/18639	0.27906976744186	1.41809743602749	0.0410382341553043	0.159445609762226
GO:0003707	nuclear steroid receptor activity	9/3668	25/18639	0.36	1.82934569247546	0.0425494653414261	0.161780385635379
GO:0015645	fatty acid ligase activity	9/3668	25/18639	0.36	1.82934569247546	0.0425494653414261	0.161780385635379
GO:0015662	P-type ion transporter activity	9/3668	25/18639	0.36	1.82934569247546	0.0425494653414261	0.161780385635379
GO:0042974	nuclear retinoic acid receptor binding	9/3668	25/18639	0.36	1.82934569247546	0.0425494653414261	0.161780385635379
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	9/3668	25/18639	0.36	1.82934569247546	0.0425494653414261	0.161780385635379
GO:0120515	fatty acid-CoA ligase activity	9/3668	25/18639	0.36	1.82934569247546	0.0425494653414261	0.161780385635379
GO:0140358	P-type transmembrane transporter activity	9/3668	25/18639	0.36	1.82934569247546	0.0425494653414261	0.161780385635379
GO:0004175	endopeptidase activity	94/3668	405/18639	0.232098765432099	1.17941354658912	0.0426189055269582	0.161780385635379
GO:0019905	syntaxin binding	18/3668	61/18639	0.295081967213115	1.49946368235694	0.0429138140640597	0.162420822539834
GO:0005496	steroid binding	29/3668	108/18639	0.268518518518519	1.36448109778262	0.043033526032507	0.162420822539834
GO:0019209	kinase activator activity	38/3668	148/18639	0.256756756756757	1.30471351940818	0.0443189003736122	0.166795633599834
GO:0003684	damaged DNA binding	21/3668	74/18639	0.283783783783784	1.44205178460904	0.045381482893489	0.169091068386343
GO:0060590	ATPase regulator activity	15/3668	49/18639	0.306122448979592	1.55556606503016	0.0455019933603695	0.169091068386343
GO:0051539	4 iron, 4 sulfur cluster binding	14/3668	45/18639	0.311111111111111	1.58091603053435	0.0460396860359488	0.169091068386343
GO:0019903	protein phosphatase binding	37/3668	144/18639	0.256944444444444	1.30566725736096	0.0462384150299176	0.169091068386343
GO:0016877	ligase activity, forming carbon-sulfur bonds	13/3668	41/18639	0.317073170731707	1.61121233077107	0.0463172674751963	0.169091068386343
GO:0000014	single-stranded DNA endodeoxyribonuclease activity	5/3668	11/18639	0.454545454545455	2.30977991474175	0.0473124355311989	0.169091068386343
GO:0001163	RNA polymerase I transcription regulatory region sequence-specific DNA binding	5/3668	11/18639	0.454545454545455	2.30977991474175	0.0473124355311989	0.169091068386343
GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity	5/3668	11/18639	0.454545454545455	2.30977991474175	0.0473124355311989	0.169091068386343
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	5/3668	11/18639	0.454545454545455	2.30977991474175	0.0473124355311989	0.169091068386343
GO:0032404	mismatch repair complex binding	5/3668	11/18639	0.454545454545455	2.30977991474175	0.0473124355311989	0.169091068386343
GO:0034056	estrogen response element binding	5/3668	11/18639	0.454545454545455	2.30977991474175	0.0473124355311989	0.169091068386343
GO:0035252	UDP-xylosyltransferase activity	5/3668	11/18639	0.454545454545455	2.30977991474175	0.0473124355311989	0.169091068386343
GO:0042285	xylosyltransferase activity	5/3668	11/18639	0.454545454545455	2.30977991474175	0.0473124355311989	0.169091068386343
GO:0045294	alpha-catenin binding	5/3668	11/18639	0.454545454545455	2.30977991474175	0.0473124355311989	0.169091068386343
GO:0047676	arachidonate-CoA ligase activity	5/3668	11/18639	0.454545454545455	2.30977991474175	0.0473124355311989	0.169091068386343
GO:0000400	four-way junction DNA binding	7/3668	18/18639	0.388888888888889	1.97614503816794	0.0473608594269091	0.169091068386343
GO:0008409	5'-3' exonuclease activity	7/3668	18/18639	0.388888888888889	1.97614503816794	0.0473608594269091	0.169091068386343
GO:0017128	phospholipid scramblase activity	7/3668	18/18639	0.388888888888889	1.97614503816794	0.0473608594269091	0.169091068386343
GO:0034185	apolipoprotein binding	7/3668	18/18639	0.388888888888889	1.97614503816794	0.0473608594269091	0.169091068386343
GO:0031072	heat shock protein binding	34/3668	131/18639	0.259541984732824	1.31886669940979	0.0477483880389761	0.170015149863847
GO:0004519	endonuclease activity	33/3668	127/18639	0.259842519685039	1.32039387252166	0.0498098923291056	0.176878676792335
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	110/3668	484/18639	0.227272727272727	1.15488995737087	0.0511820277900153	0.181263964371609
GO:0070034	telomerase RNA binding	8/3668	22/18639	0.363636363636364	1.8478239317934	0.0515484073451655	0.18158785627457
GO:0140517	protein-RNA adaptor activity	8/3668	22/18639	0.363636363636364	1.8478239317934	0.0515484073451655	0.18158785627457
GO:0004222	metalloendopeptidase activity	29/3668	110/18639	0.263636363636364	1.33967235055021	0.0533000587447344	0.187258982983495
GO:0008138	protein tyrosine/serine/threonine phosphatase activity	9/3668	26/18639	0.346153846153846	1.75898624276487	0.054072322806464	0.189468271690554
GO:0042054	histone methyltransferase activity	19/3668	67/18639	0.283582089552239	1.44102687218216	0.0554085980797004	0.193131587854715
GO:0035198	miRNA binding	13/3668	42/18639	0.30952380952381	1.57285013241938	0.0554101981808758	0.193131587854715
GO:0008175	tRNA methyltransferase activity	11/3668	34/18639	0.323529411764706	1.64401982166913	0.0559632320770558	0.19352730254919
GO:0008376	acetylgalactosaminyltransferase activity	11/3668	34/18639	0.323529411764706	1.64401982166913	0.0559632320770558	0.19352730254919
GO:0015035	protein-disulfide reductase activity	11/3668	34/18639	0.323529411764706	1.64401982166913	0.0559632320770558	0.19352730254919
GO:0051219	phosphoprotein binding	25/3668	93/18639	0.268817204301075	1.36599887430964	0.0564362160343586	0.19465337175297
GO:0004467	long-chain fatty acid-CoA ligase activity	6/3668	15/18639	0.4	2.03260632497274	0.0569300210382916	0.194830460599956
GO:0120283	protein serine/threonine kinase binding	6/3668	15/18639	0.4	2.03260632497274	0.0569300210382916	0.194830460599956
GO:0140776	protein-containing complex destabilizing activity	6/3668	15/18639	0.4	2.03260632497274	0.0569300210382916	0.194830460599956
GO:0003727	single-stranded RNA binding	24/3668	89/18639	0.269662921348315	1.37029639885803	0.0587679398857354	0.200600642348983
GO:0004879	nuclear receptor activity	17/3668	59/18639	0.288135593220339	1.46416557307358	0.059085589237824	0.201165111812282
GO:0016830	carbon-carbon lyase activity	15/3668	51/18639	0.294117647058824	1.49456347424466	0.0625983545722721	0.211647017771981
GO:0008381	mechanosensitive monoatomic ion channel activity	7/3668	19/18639	0.368421052631579	1.87213740458015	0.0626449537841366	0.211647017771981
GO:0015245	fatty acid transmembrane transporter activity	7/3668	19/18639	0.368421052631579	1.87213740458015	0.0626449537841366	0.211647017771981
GO:0005548	phospholipid transporter activity	19/3668	68/18639	0.279411764705882	1.41983530053243	0.063223485657271	0.213056695288916
GO:0008237	metallopeptidase activity	45/3668	184/18639	0.244565217391304	1.24276201934474	0.0639407390979959	0.214720652468961
GO:0000287	magnesium ion binding	55/3668	230/18639	0.239130434782609	1.21514508558153	0.064057206210499	0.214720652468961
GO:0140359	ABC-type transporter activity	14/3668	47/18639	0.297872340425532	1.51364300795842	0.064204888512672	0.214720652468961
GO:0004536	DNA nuclease activity	18/3668	64/18639	0.28125	1.42917632224646	0.0655463634587651	0.21848044997077
GO:0051082	unfolded protein binding	31/3668	121/18639	0.256198347107438	1.30187595194535	0.0657757258454144	0.21848044997077
GO:0008171	O-methyltransferase activity	8/3668	23/18639	0.347826086956522	1.76748376084586	0.0658652138562346	0.21848044997077
GO:0030295	protein kinase activator activity	35/3668	139/18639	0.251798561151079	1.27951837003679	0.0660708279716345	0.21848044997077
GO:0008266	poly(U) RNA binding	9/3668	27/18639	0.333333333333333	1.69383860414395	0.0674444971942476	0.21848044997077
GO:0001098	basal transcription machinery binding	17/3668	60/18639	0.283333333333333	1.43976281352236	0.0678945165505124	0.21848044997077
GO:0001099	basal RNA polymerase II transcription machinery binding	17/3668	60/18639	0.283333333333333	1.43976281352236	0.0678945165505124	0.21848044997077
GO:0004714	transmembrane receptor protein tyrosine kinase activity	17/3668	60/18639	0.283333333333333	1.43976281352236	0.0678945165505124	0.21848044997077
GO:0098531	ligand-modulated transcription factor activity	17/3668	60/18639	0.283333333333333	1.43976281352236	0.0678945165505124	0.21848044997077
GO:0016411	acylglycerol O-acyltransferase activity	10/3668	31/18639	0.32258064516129	1.63919864917156	0.0679174263254783	0.21848044997077
GO:0005078	MAP-kinase scaffold activity	5/3668	12/18639	0.416666666666667	2.11729825517993	0.0683061512777653	0.21848044997077
GO:0005095	GTPase inhibitor activity	5/3668	12/18639	0.416666666666667	2.11729825517993	0.0683061512777653	0.21848044997077
GO:0005247	voltage-gated chloride channel activity	5/3668	12/18639	0.416666666666667	2.11729825517993	0.0683061512777653	0.21848044997077
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	5/3668	12/18639	0.416666666666667	2.11729825517993	0.0683061512777653	0.21848044997077
GO:0035014	phosphatidylinositol 3-kinase regulator activity	5/3668	12/18639	0.416666666666667	2.11729825517993	0.0683061512777653	0.21848044997077
GO:0035251	UDP-glucosyltransferase activity	5/3668	12/18639	0.416666666666667	2.11729825517993	0.0683061512777653	0.21848044997077
GO:0035497	cAMP response element binding	5/3668	12/18639	0.416666666666667	2.11729825517993	0.0683061512777653	0.21848044997077
GO:0043047	single-stranded telomeric DNA binding	5/3668	12/18639	0.416666666666667	2.11729825517993	0.0683061512777653	0.21848044997077
GO:0003779	actin binding	100/3668	443/18639	0.225733634311512	1.14706903215166	0.069808304219904	0.222745820952882
GO:0008757	S-adenosylmethionine-dependent methyltransferase activity	41/3668	167/18639	0.245508982035928	1.24755777430961	0.0704855372053039	0.22436480638122
GO:0001216	DNA-binding transcription activator activity	110/3668	491/18639	0.224032586558045	1.13842513109471	0.0709123354469834	0.225180757513137
GO:0016279	protein-lysine N-methyltransferase activity	19/3668	69/18639	0.27536231884058	1.3992579773363	0.0717633975256793	0.227336806070557
GO:0008168	methyltransferase activity	49/3668	204/18639	0.240196078431373	1.22056017063314	0.072000014925922	0.227540717026658
GO:0005080	protein kinase C binding	15/3668	52/18639	0.288461538461538	1.46582186897072	0.0725841928727318	0.228839424307586
GO:0120013	lipid transfer activity	18/3668	65/18639	0.276923076923077	1.40718899421189	0.0746185588148913	0.234693133796361
GO:0140693	molecular condensate scaffold activity	14/3668	48/18639	0.291666666666667	1.48210877862595	0.0748636492206839	0.234904704561813
GO:0044325	transmembrane transporter binding	34/3668	136/18639	0.25	1.27037895310796	0.0752958913434204	0.235701119584498
GO:0003688	DNA replication origin binding	6/3668	16/18639	0.375	1.90556842966194	0.0764101528804132	0.237500734011825
GO:0005159	insulin-like growth factor receptor binding	6/3668	16/18639	0.375	1.90556842966194	0.0764101528804132	0.237500734011825
GO:0140328	floppase activity	6/3668	16/18639	0.375	1.90556842966194	0.0764101528804132	0.237500734011825
GO:0001046	core promoter sequence-specific DNA binding	13/3668	44/18639	0.295454545454545	1.50135694458214	0.0770373086883605	0.238887992435033
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	7/3668	20/18639	0.35	1.77853053435114	0.0805911678728153	0.247009124733153
GO:0015095	magnesium ion transmembrane transporter activity	7/3668	20/18639	0.35	1.77853053435114	0.0805911678728153	0.247009124733153
GO:0031418	L-ascorbic acid binding	7/3668	20/18639	0.35	1.77853053435114	0.0805911678728153	0.247009124733153
GO:0052745	inositol phosphate phosphatase activity	7/3668	20/18639	0.35	1.77853053435114	0.0805911678728153	0.247009124733153
GO:0061608	nuclear import signal receptor activity	7/3668	20/18639	0.35	1.77853053435114	0.0805911678728153	0.247009124733153
GO:0016278	lysine N-methyltransferase activity	19/3668	70/18639	0.271428571428571	1.37926857766007	0.081047038359206	0.247259795732838
GO:0016741	transferase activity, transferring one-carbon groups	51/3668	215/18639	0.237209302325581	1.20538282062337	0.081047306247024	0.247259795732838
GO:0051019	mitogen-activated protein kinase binding	9/3668	28/18639	0.321428571428571	1.63334436828166	0.082711278494807	0.251754836155853
GO:0008235	metalloexopeptidase activity	18/3668	66/18639	0.272727272727273	1.38586794884505	0.0844896306392648	0.256576556493032
GO:0042277	peptide binding	58/3668	249/18639	0.232931726907631	1.18364625349818	0.0882229475555164	0.267299343396415
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	62/3668	268/18639	0.23134328358209	1.17557455362229	0.0894223172863433	0.27031322914247
GO:0035591	signaling adaptor activity	32/3668	129/18639	0.248062015503876	1.26053105424666	0.0896748707007191	0.270457772136187
GO:0061980	regulatory RNA binding	16/3668	58/18639	0.275862068965517	1.40179746549844	0.0917484644081473	0.276081370121099
GO:0001217	DNA-binding transcription repressor activity	64/3668	278/18639	0.23021582733813	1.16984536689078	0.0924444700786026	0.277543511304168
GO:0008417	fucosyltransferase activity	5/3668	13/18639	0.384615384615385	1.95442915862763	0.0936041028345071	0.278493287937802
GO:0043560	insulin receptor substrate binding	5/3668	13/18639	0.384615384615385	1.95442915862763	0.0936041028345071	0.278493287937802
GO:0046974	histone H3K9 methyltransferase activity	5/3668	13/18639	0.384615384615385	1.95442915862763	0.0936041028345071	0.278493287937802
GO:0046975	histone H3K36 methyltransferase activity	5/3668	13/18639	0.384615384615385	1.95442915862763	0.0936041028345071	0.278493287937802
GO:0019888	protein phosphatase regulator activity	27/3668	107/18639	0.252336448598131	1.2822516536043	0.0947702360682298	0.281329172687936
GO:0008173	RNA methyltransferase activity	18/3668	67/18639	0.26865671641791	1.36518335259363	0.0951724589264516	0.281797086955216
GO:0019213	deacetylase activity	11/3668	37/18639	0.297297297297297	1.51072091720947	0.0953545025503267	0.281797086955216
GO:0140311	protein sequestering activity	10/3668	33/18639	0.303030303030303	1.5398532764945	0.0978530272589728	0.288535377252462
GO:0032183	SUMO binding	6/3668	17/18639	0.352941176470588	1.79347616909359	0.0991731880316668	0.291128403088515
GO:0070403	NAD+ binding	6/3668	17/18639	0.352941176470588	1.79347616909359	0.0991731880316668	0.291128403088515
GO:1901682	sulfur compound transmembrane transporter activity	17/3668	63/18639	0.26984126984127	1.3712026795451	0.0994422710473626	0.291271042247375
GO:0106222	lncRNA binding	9/3668	29/18639	0.310344827586207	1.57702214868574	0.0998826545416798	0.291913687277785
GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity	7/3668	21/18639	0.333333333333333	1.69383860414395	0.101187599347457	0.295074655050753
GO:0019208	phosphatase regulator activity	29/3668	117/18639	0.247863247863248	1.25952101333781	0.102937484884013	0.299516338175729
GO:0045309	protein phosphorylated amino acid binding	16/3668	59/18639	0.271186440677966	1.37803818642219	0.1039020923785	0.301658602268129
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	18/3668	68/18639	0.264705882352941	1.34510712682019	0.106674089303357	0.309027350810821
GO:0004520	DNA endonuclease activity	12/3668	42/18639	0.285714285714286	1.45186166069481	0.107437878390385	0.310558943881179
GO:0043531	ADP binding	11/3668	38/18639	0.289473684210526	1.47096510359869	0.111428025042175	0.321389565678414
GO:0016597	amino acid binding	14/3668	51/18639	0.274509803921569	1.39492590929502	0.113396592757534	0.323192461514529
GO:0001164	RNA polymerase I core promoter sequence-specific DNA binding	4/3668	10/18639	0.4	2.03260632497274	0.115233648276566	0.323192461514529
GO:0004090	carbonyl reductase (NADPH) activity	4/3668	10/18639	0.4	2.03260632497274	0.115233648276566	0.323192461514529
GO:0005337	nucleoside transmembrane transporter activity	4/3668	10/18639	0.4	2.03260632497274	0.115233648276566	0.323192461514529
GO:0005345	purine nucleobase transmembrane transporter activity	4/3668	10/18639	0.4	2.03260632497274	0.115233648276566	0.323192461514529
GO:0008297	single-stranded DNA exodeoxyribonuclease activity	4/3668	10/18639	0.4	2.03260632497274	0.115233648276566	0.323192461514529
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	4/3668	10/18639	0.4	2.03260632497274	0.115233648276566	0.323192461514529
GO:0015643	toxic substance binding	4/3668	10/18639	0.4	2.03260632497274	0.115233648276566	0.323192461514529
GO:0031957	very long-chain fatty acid-CoA ligase activity	4/3668	10/18639	0.4	2.03260632497274	0.115233648276566	0.323192461514529
GO:0051864	histone H3K36 demethylase activity	4/3668	10/18639	0.4	2.03260632497274	0.115233648276566	0.323192461514529
GO:0051880	G-quadruplex DNA binding	4/3668	10/18639	0.4	2.03260632497274	0.115233648276566	0.323192461514529
GO:0070097	delta-catenin binding	4/3668	10/18639	0.4	2.03260632497274	0.115233648276566	0.323192461514529
GO:0098505	G-rich strand telomeric DNA binding	4/3668	10/18639	0.4	2.03260632497274	0.115233648276566	0.323192461514529
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	16/3668	60/18639	0.266666666666667	1.35507088331516	0.11699575631595	0.327439394265615
GO:0005516	calmodulin binding	48/3668	207/18639	0.231884057971014	1.17832250723057	0.118405520604879	0.330035774388511
GO:0001784	phosphotyrosine residue binding	13/3668	47/18639	0.276595744680851	1.40552565024711	0.118423131763932	0.330035774388511
GO:0008187	poly-pyrimidine tract binding	9/3668	30/18639	0.3	1.52445474372955	0.118933211218907	0.330064647101209
GO:0016769	transferase activity, transferring nitrogenous groups	9/3668	30/18639	0.3	1.52445474372955	0.118933211218907	0.330064647101209
GO:0008174	mRNA methyltransferase activity	5/3668	14/18639	0.357142857142857	1.81482707586852	0.122959318595426	0.334216584083451
GO:0008474	palmitoyl-(protein) hydrolase activity	5/3668	14/18639	0.357142857142857	1.81482707586852	0.122959318595426	0.334216584083451
GO:0015926	glucosidase activity	5/3668	14/18639	0.357142857142857	1.81482707586852	0.122959318595426	0.334216584083451
GO:0030983	mismatched DNA binding	5/3668	14/18639	0.357142857142857	1.81482707586852	0.122959318595426	0.334216584083451
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity	5/3668	14/18639	0.357142857142857	1.81482707586852	0.122959318595426	0.334216584083451
GO:0042043	neurexin family protein binding	5/3668	14/18639	0.357142857142857	1.81482707586852	0.122959318595426	0.334216584083451
GO:0046030	inositol trisphosphate phosphatase activity	5/3668	14/18639	0.357142857142857	1.81482707586852	0.122959318595426	0.334216584083451
GO:0070742	C2H2 zinc finger domain binding	5/3668	14/18639	0.357142857142857	1.81482707586852	0.122959318595426	0.334216584083451
GO:0098599	palmitoyl hydrolase activity	5/3668	14/18639	0.357142857142857	1.81482707586852	0.122959318595426	0.334216584083451
GO:0098847	sequence-specific single stranded DNA binding	5/3668	14/18639	0.357142857142857	1.81482707586852	0.122959318595426	0.334216584083451
GO:0004407	histone deacetylase activity	7/3668	22/18639	0.318181818181818	1.61684594031922	0.124352555615194	0.335244338709532
GO:0033558	protein lysine deacetylase activity	7/3668	22/18639	0.318181818181818	1.61684594031922	0.124352555615194	0.335244338709532
GO:0034062	5'-3' RNA polymerase activity	7/3668	22/18639	0.318181818181818	1.61684594031922	0.124352555615194	0.335244338709532
GO:0097747	RNA polymerase activity	7/3668	22/18639	0.318181818181818	1.61684594031922	0.124352555615194	0.335244338709532
GO:0160215	deacylase activity	17/3668	65/18639	0.261538461538462	1.32901182786679	0.12483638627748	0.335863271430858
GO:0030159	signaling receptor complex adaptor activity	14/3668	52/18639	0.269230769230769	1.36810041103934	0.128432740083513	0.34483668628114
GO:0000217	DNA secondary structure binding	11/3668	39/18639	0.282051282051282	1.43324804966026	0.128953394961786	0.345532321996997
GO:0016504	peptidase activator activity	15/3668	57/18639	0.263157894736842	1.33724100327154	0.137580148034437	0.367199879147037
GO:0015294	solute:monoatomic cation symporter activity	28/3668	116/18639	0.241379310344828	1.22657278231113	0.137595715501728	0.367199879147037
GO:0016790	thiolester hydrolase activity	12/3668	44/18639	0.272727272727273	1.38586794884505	0.141086220681323	0.375755841774249
GO:0043022	ribosome binding	27/3668	112/18639	0.241071428571429	1.22500827621125	0.144319942374429	0.383407468004159
GO:0016860	intramolecular oxidoreductase activity	14/3668	53/18639	0.264150943396226	1.34228719573671	0.14453968135206	0.383407468004159
GO:0019207	kinase regulator activity	64/3668	287/18639	0.222996515679443	1.13316032054229	0.146995211204881	0.38913962725781
GO:0071949	FAD binding	11/3668	40/18639	0.275	1.39741684841876	0.147888104835055	0.390720372974215
GO:1990782	protein tyrosine kinase binding	28/3668	117/18639	0.239316239316239	1.21608925425719	0.148499428505055	0.391552385339676
GO:0003887	DNA-directed DNA polymerase activity	7/3668	23/18639	0.304347826086957	1.54654829074013	0.149940767634738	0.392999511995019
GO:0042171	lysophosphatidic acid acyltransferase activity	7/3668	23/18639	0.304347826086957	1.54654829074013	0.149940767634738	0.392999511995019
GO:0071617	lysophospholipid acyltransferase activity	7/3668	23/18639	0.304347826086957	1.54654829074013	0.149940767634738	0.392999511995019
GO:0001222	transcription corepressor binding	13/3668	49/18639	0.26530612244898	1.34815725635947	0.151933555232702	0.395903622501368
GO:0042577	lipid phosphatase activity	6/3668	19/18639	0.315789473684211	1.60468920392585	0.153895228587849	0.395903622501368
GO:0046624	sphingolipid transporter activity	6/3668	19/18639	0.315789473684211	1.60468920392585	0.153895228587849	0.395903622501368
GO:0120227	acyl-CoA binding	6/3668	19/18639	0.315789473684211	1.60468920392585	0.153895228587849	0.395903622501368
GO:0004143	ATP-dependent diacylglycerol kinase activity	4/3668	11/18639	0.363636363636364	1.8478239317934	0.154045769845347	0.395903622501368
GO:0008172	S-methyltransferase activity	4/3668	11/18639	0.363636363636364	1.8478239317934	0.154045769845347	0.395903622501368
GO:0008432	JUN kinase binding	4/3668	11/18639	0.363636363636364	1.8478239317934	0.154045769845347	0.395903622501368
GO:0015205	nucleobase transmembrane transporter activity	4/3668	11/18639	0.363636363636364	1.8478239317934	0.154045769845347	0.395903622501368
GO:0032794	GTPase activating protein binding	4/3668	11/18639	0.363636363636364	1.8478239317934	0.154045769845347	0.395903622501368
GO:0140537	transcription regulator activator activity	4/3668	11/18639	0.363636363636364	1.8478239317934	0.154045769845347	0.395903622501368
GO:0008514	organic anion transmembrane transporter activity	60/3668	269/18639	0.223048327137546	1.13342360128591	0.155341502556414	0.398458494906841
GO:0000774	adenyl-nucleotide exchange factor activity	5/3668	15/18639	0.333333333333333	1.69383860414395	0.155973967373993	0.399305447482644
GO:0042826	histone deacetylase binding	30/3668	127/18639	0.236220472440945	1.20035806592878	0.156285407317559	0.399328864732099
GO:0015293	symporter activity	34/3668	146/18639	0.232876712328767	1.18336669604577	0.15930745668527	0.406264768882705
GO:0015485	cholesterol binding	14/3668	54/18639	0.259259259259259	1.31743002544529	0.161685609593966	0.410743635141595
GO:0050661	NADP binding	14/3668	54/18639	0.259259259259259	1.31743002544529	0.161685609593966	0.410743635141595
GO:0051059	NF-kappaB binding	9/3668	32/18639	0.28125	1.42917632224646	0.162401341432803	0.410981172476499
GO:0120015	sterol transfer activity	9/3668	32/18639	0.28125	1.42917632224646	0.162401341432803	0.410981172476499
GO:0097718	disordered domain specific binding	8/3668	28/18639	0.285714285714286	1.45186166069481	0.170027256529875	0.42945699020261
GO:0033218	amide binding	55/3668	247/18639	0.222672064777328	1.13151161815284	0.170752212117425	0.430465023296026
GO:0004521	RNA endonuclease activity	18/3668	73/18639	0.246575342465753	1.25297650169552	0.176282013580379	0.443559123694629
GO:0015295	solute:proton symporter activity	7/3668	24/18639	0.291666666666667	1.48210877862595	0.177751914741916	0.445560302417592
GO:0050699	WW domain binding	7/3668	24/18639	0.291666666666667	1.48210877862595	0.177751914741916	0.445560302417592
GO:0016004	phospholipase activator activity	6/3668	20/18639	0.3	1.52445474372955	0.185311254608578	0.463629104806689
GO:0001540	amyloid-beta binding	20/3668	83/18639	0.240963855421687	1.22446164154984	0.188597879372189	0.470029749939661
GO:0005010	insulin-like growth factor receptor activity	13/3668	51/18639	0.254901960784314	1.29528834434537	0.18986496662766	0.470029749939661
GO:0005021	vascular endothelial growth factor receptor activity	13/3668	51/18639	0.254901960784314	1.29528834434537	0.18986496662766	0.470029749939661
GO:0030544	Hsp70 protein binding	13/3668	51/18639	0.254901960784314	1.29528834434537	0.18986496662766	0.470029749939661
GO:0031406	carboxylic acid binding	42/3668	187/18639	0.224598930481283	1.14130301669592	0.191185212950166	0.470029749939661
GO:0000062	fatty-acyl-CoA binding	5/3668	16/18639	0.3125	1.58797369138495	0.192139337598347	0.470029749939661
GO:0004697	diacylglycerol-dependent serine/threonine kinase activity	5/3668	16/18639	0.3125	1.58797369138495	0.192139337598347	0.470029749939661
GO:0008142	oxysterol binding	5/3668	16/18639	0.3125	1.58797369138495	0.192139337598347	0.470029749939661
GO:0015562	efflux transmembrane transporter activity	5/3668	16/18639	0.3125	1.58797369138495	0.192139337598347	0.470029749939661
GO:0016722	oxidoreductase activity, acting on metal ions	5/3668	16/18639	0.3125	1.58797369138495	0.192139337598347	0.470029749939661
GO:0031435	mitogen-activated protein kinase kinase kinase binding	5/3668	16/18639	0.3125	1.58797369138495	0.192139337598347	0.470029749939661
GO:0106018	phosphatidylinositol-3,5-bisphosphate phosphatase activity	5/3668	16/18639	0.3125	1.58797369138495	0.192139337598347	0.470029749939661
GO:0004300	enoyl-CoA hydratase activity	4/3668	12/18639	0.333333333333333	1.69383860414395	0.196915579129138	0.474681532900714
GO:0016423	tRNA (guanine) methyltransferase activity	4/3668	12/18639	0.333333333333333	1.69383860414395	0.196915579129138	0.474681532900714
GO:0031543	peptidyl-proline dioxygenase activity	4/3668	12/18639	0.333333333333333	1.69383860414395	0.196915579129138	0.474681532900714
GO:0034452	dynactin binding	4/3668	12/18639	0.333333333333333	1.69383860414395	0.196915579129138	0.474681532900714
GO:0035197	siRNA binding	4/3668	12/18639	0.333333333333333	1.69383860414395	0.196915579129138	0.474681532900714
GO:0052629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	4/3668	12/18639	0.333333333333333	1.69383860414395	0.196915579129138	0.474681532900714
GO:0070410	co-SMAD binding	4/3668	12/18639	0.333333333333333	1.69383860414395	0.196915579129138	0.474681532900714
GO:0097371	MDM2/MDM4 family protein binding	4/3668	12/18639	0.333333333333333	1.69383860414395	0.196915579129138	0.474681532900714
GO:0030170	pyridoxal phosphate binding	14/3668	56/18639	0.25	1.27037895310796	0.19891483137668	0.478627490434597
GO:0005537	D-mannose binding	7/3668	25/18639	0.28	1.42282442748092	0.207540643819952	0.496668823344487
GO:0008483	transaminase activity	7/3668	25/18639	0.28	1.42282442748092	0.207540643819952	0.496668823344487
GO:0016895	DNA exonuclease activity, producing 5'-phosphomonoesters	7/3668	25/18639	0.28	1.42282442748092	0.207540643819952	0.496668823344487
GO:0043177	organic acid binding	42/3668	189/18639	0.222222222222222	1.12922573609596	0.21221288894711	0.506931693126823
GO:0070279	vitamin B6 binding	14/3668	57/18639	0.245614035087719	1.24809160305344	0.218884263162526	0.521165958158393
GO:0009931	calcium-dependent protein serine/threonine kinase activity	6/3668	21/18639	0.285714285714286	1.45186166069481	0.218960716713027	0.521165958158393
GO:0008106	alcohol dehydrogenase (NADP+) activity	8/3668	30/18639	0.266666666666667	1.35507088331516	0.225045663649809	0.53416681899714
GO:0016776	phosphotransferase activity, phosphate group as acceptor	10/3668	39/18639	0.256410256410256	1.30295277241842	0.225231580758067	0.53416681899714
GO:0004549	tRNA-specific ribonuclease activity	5/3668	17/18639	0.294117647058824	1.49456347424466	0.230875233251131	0.539798554203086
GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity	5/3668	17/18639	0.294117647058824	1.49456347424466	0.230875233251131	0.539798554203086
GO:0005092	GDP-dissociation inhibitor activity	5/3668	17/18639	0.294117647058824	1.49456347424466	0.230875233251131	0.539798554203086
GO:0015278	intracellularly gated calcium channel activity	5/3668	17/18639	0.294117647058824	1.49456347424466	0.230875233251131	0.539798554203086
GO:0032977	membrane insertase activity	5/3668	17/18639	0.294117647058824	1.49456347424466	0.230875233251131	0.539798554203086
GO:0046965	nuclear retinoid X receptor binding	5/3668	17/18639	0.294117647058824	1.49456347424466	0.230875233251131	0.539798554203086
GO:1901567	fatty acid derivative binding	5/3668	17/18639	0.294117647058824	1.49456347424466	0.230875233251131	0.539798554203086
GO:1990226	histone methyltransferase binding	5/3668	17/18639	0.294117647058824	1.49456347424466	0.230875233251131	0.539798554203086
GO:0140296	general transcription initiation factor binding	13/3668	53/18639	0.245283018867925	1.24640953889838	0.231728251065894	0.540835723777467
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	16/3668	67/18639	0.238805970149254	1.21349631341656	0.233359765184317	0.543682980261874
GO:0016874	ligase activity	37/3668	167/18639	0.221556886227545	1.12584482071843	0.235635978059753	0.548019589818544
GO:0043014	alpha-tubulin binding	11/3668	44/18639	0.25	1.27037895310796	0.236228955288713	0.548433128183462
GO:0004529	DNA exonuclease activity	7/3668	26/18639	0.269230769230769	1.36810041103934	0.239027333656116	0.552986178213187
GO:0005160	transforming growth factor beta receptor binding	7/3668	26/18639	0.269230769230769	1.36810041103934	0.239027333656116	0.552986178213187
GO:0019104	DNA N-glycosylase activity	4/3668	13/18639	0.307692307692308	1.56354332690211	0.24283179081564	0.557879644639062
GO:0035673	oligopeptide transmembrane transporter activity	4/3668	13/18639	0.307692307692308	1.56354332690211	0.24283179081564	0.557879644639062
GO:0061459	L-arginine transmembrane transporter activity	4/3668	13/18639	0.307692307692308	1.56354332690211	0.24283179081564	0.557879644639062
GO:0140333	glycerophospholipid flippase activity	4/3668	13/18639	0.307692307692308	1.56354332690211	0.24283179081564	0.557879644639062
GO:0019887	protein kinase regulator activity	55/3668	255/18639	0.215686274509804	1.09601321444608	0.244129335523958	0.559886896227689
GO:0140662	ATP-dependent protein folding chaperone	10/3668	40/18639	0.25	1.27037895310796	0.251012739399071	0.57467561307829
GO:0051287	NAD binding	13/3668	54/18639	0.240740740740741	1.22332788077063	0.253936893483823	0.57809679101089
GO:0140035	ubiquitin-like protein reader activity	6/3668	22/18639	0.272727272727273	1.38586794884505	0.254438777124714	0.57809679101089
GO:0017147	Wnt-protein binding	8/3668	31/18639	0.258064516129032	1.31135891933725	0.254695179688371	0.57809679101089
GO:0070273	phosphatidylinositol-4-phosphate binding	8/3668	31/18639	0.258064516129032	1.31135891933725	0.254695179688371	0.57809679101089
GO:0072349	modified amino acid transmembrane transporter activity	8/3668	31/18639	0.258064516129032	1.31135891933725	0.254695179688371	0.57809679101089
GO:0004190	aspartic-type endopeptidase activity	9/3668	36/18639	0.25	1.27037895310796	0.267318655216128	0.604699889086667
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	19/3668	83/18639	0.228915662650602	1.16323855947235	0.268634394532161	0.604699889086667
GO:0005006	epidermal growth factor receptor activity	12/3668	50/18639	0.24	1.21956379498364	0.269480151717084	0.604699889086667
GO:0005017	platelet-derived growth factor receptor activity	12/3668	50/18639	0.24	1.21956379498364	0.269480151717084	0.604699889086667
GO:0005019	platelet-derived growth factor beta-receptor activity	12/3668	50/18639	0.24	1.21956379498364	0.269480151717084	0.604699889086667
GO:0000900	mRNA regulatory element binding translation repressor activity	5/3668	18/18639	0.277777777777778	1.41153217011996	0.271565956680779	0.604699889086667
GO:0008308	voltage-gated monoatomic anion channel activity	5/3668	18/18639	0.277777777777778	1.41153217011996	0.271565956680779	0.604699889086667
GO:0017075	syntaxin-1 binding	5/3668	18/18639	0.277777777777778	1.41153217011996	0.271565956680779	0.604699889086667
GO:0001671	ATPase activator activity	7/3668	27/18639	0.259259259259259	1.31743002544529	0.271908958453808	0.604699889086667
GO:0005044	scavenger receptor activity	7/3668	27/18639	0.259259259259259	1.31743002544529	0.271908958453808	0.604699889086667
GO:0008320	protein transmembrane transporter activity	7/3668	27/18639	0.259259259259259	1.31743002544529	0.271908958453808	0.604699889086667
GO:0034593	phosphatidylinositol bisphosphate phosphatase activity	7/3668	27/18639	0.259259259259259	1.31743002544529	0.271908958453808	0.604699889086667
GO:0031491	nucleosome binding	17/3668	74/18639	0.22972972972973	1.16737525420732	0.278519901638868	0.61836099170579
GO:0008170	N-methyltransferase activity	22/3668	98/18639	0.224489795918367	1.14074844768878	0.280533886477861	0.621787355767206
GO:0022884	macromolecule transmembrane transporter activity	8/3668	32/18639	0.25	1.27037895310796	0.285459792440227	0.630589273935686
GO:0043425	bHLH transcription factor binding	8/3668	32/18639	0.25	1.27037895310796	0.285459792440227	0.630589273935686
GO:0008195	phosphatidate phosphatase activity	4/3668	14/18639	0.285714285714286	1.45186166069481	0.290780779703726	0.635962599318911
GO:0008559	ABC-type xenobiotic transporter activity	4/3668	14/18639	0.285714285714286	1.45186166069481	0.290780779703726	0.635962599318911
GO:0052816	long-chain fatty acyl-CoA hydrolase activity	4/3668	14/18639	0.285714285714286	1.45186166069481	0.290780779703726	0.635962599318911
GO:0071933	Arp2/3 complex binding	4/3668	14/18639	0.285714285714286	1.45186166069481	0.290780779703726	0.635962599318911
GO:1901474	azole transmembrane transporter activity	4/3668	14/18639	0.285714285714286	1.45186166069481	0.290780779703726	0.635962599318911
GO:1901612	cardiolipin binding	4/3668	14/18639	0.285714285714286	1.45186166069481	0.290780779703726	0.635962599318911
GO:0016849	phosphorus-oxygen lyase activity	6/3668	23/18639	0.260869565217391	1.32561282063439	0.291320427532941	0.636089726894239
GO:0005030	neurotrophin receptor activity	12/3668	51/18639	0.235294117647059	1.19565077939573	0.293977131744599	0.640831338340949
GO:0042562	hormone binding	21/3668	94/18639	0.223404255319149	1.13523225596882	0.294845634802194	0.641665706052221
GO:0070001	aspartic-type peptidase activity	9/3668	37/18639	0.243243243243243	1.23604438680775	0.296319737438295	0.643813113743401
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	28/3668	128/18639	0.21875	1.11158158396947	0.297504217622348	0.645255447475314
GO:0044183	protein folding chaperone	17/3668	75/18639	0.226666666666667	1.15181025081788	0.298774036873371	0.645255447475314
GO:0019894	kinesin binding	10/3668	42/18639	0.238095238095238	1.20988471724568	0.305240917543651	0.645255447475314
GO:0051879	Hsp90 protein binding	10/3668	42/18639	0.238095238095238	1.20988471724568	0.305240917543651	0.645255447475314
GO:0046875	ephrin receptor binding	7/3668	28/18639	0.25	1.27037895310796	0.305869525761785	0.645255447475314
GO:0050698	proteoglycan sulfotransferase activity	7/3668	28/18639	0.25	1.27037895310796	0.305869525761785	0.645255447475314
GO:0080025	phosphatidylinositol-3,5-bisphosphate binding	7/3668	28/18639	0.25	1.27037895310796	0.305869525761785	0.645255447475314
GO:0015026	coreceptor activity	14/3668	61/18639	0.229508196721311	1.16624953072206	0.306095634260332	0.645255447475314
GO:0004382	GDP phosphatase activity	3/3668	10/18639	0.3	1.52445474372955	0.312513597172834	0.645255447475314
GO:0004445	inositol-polyphosphate 5-phosphatase activity	3/3668	10/18639	0.3	1.52445474372955	0.312513597172834	0.645255447475314
GO:0005381	iron ion transmembrane transporter activity	3/3668	10/18639	0.3	1.52445474372955	0.312513597172834	0.645255447475314
GO:0005522	profilin binding	3/3668	10/18639	0.3	1.52445474372955	0.312513597172834	0.645255447475314
GO:0015658	branched-chain amino acid transmembrane transporter activity	3/3668	10/18639	0.3	1.52445474372955	0.312513597172834	0.645255447475314
GO:0016427	tRNA (cytidine) methyltransferase activity	3/3668	10/18639	0.3	1.52445474372955	0.312513597172834	0.645255447475314
GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	3/3668	10/18639	0.3	1.52445474372955	0.312513597172834	0.645255447475314
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	3/3668	10/18639	0.3	1.52445474372955	0.312513597172834	0.645255447475314
GO:0031078	histone H3K14 deacetylase activity, hydrolytic mechanism	3/3668	10/18639	0.3	1.52445474372955	0.312513597172834	0.645255447475314
GO:0031419	cobalamin binding	3/3668	10/18639	0.3	1.52445474372955	0.312513597172834	0.645255447475314
GO:0031434	mitogen-activated protein kinase kinase binding	3/3668	10/18639	0.3	1.52445474372955	0.312513597172834	0.645255447475314
GO:0031956	medium-chain fatty acid-CoA ligase activity	3/3668	10/18639	0.3	1.52445474372955	0.312513597172834	0.645255447475314
GO:0034739	histone H4K16 deacetylase activity, hydrolytic mechanism	3/3668	10/18639	0.3	1.52445474372955	0.312513597172834	0.645255447475314
GO:0043121	neurotrophin binding	3/3668	10/18639	0.3	1.52445474372955	0.312513597172834	0.645255447475314
GO:0043295	glutathione binding	3/3668	10/18639	0.3	1.52445474372955	0.312513597172834	0.645255447475314
GO:0070513	death domain binding	3/3668	10/18639	0.3	1.52445474372955	0.312513597172834	0.645255447475314
GO:0097177	mitochondrial ribosome binding	3/3668	10/18639	0.3	1.52445474372955	0.312513597172834	0.645255447475314
GO:0099122	RNA polymerase II C-terminal domain binding	3/3668	10/18639	0.3	1.52445474372955	0.312513597172834	0.645255447475314
GO:0140135	mechanosensitive monoatomic cation channel activity	3/3668	10/18639	0.3	1.52445474372955	0.312513597172834	0.645255447475314
GO:0180032	histone H4K5 deacetylase activity, hydrolytic mechanism	3/3668	10/18639	0.3	1.52445474372955	0.312513597172834	0.645255447475314
GO:0180033	histone H4K8 deacetylase activity, hydrolytic mechanism	3/3668	10/18639	0.3	1.52445474372955	0.312513597172834	0.645255447475314
GO:1990162	histone H3K4 deacetylase activity, hydrolytic mechanism	3/3668	10/18639	0.3	1.52445474372955	0.312513597172834	0.645255447475314
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	5/3668	19/18639	0.263157894736842	1.33724100327154	0.313591216713968	0.645255447475314
GO:0005346	purine ribonucleotide transmembrane transporter activity	5/3668	19/18639	0.263157894736842	1.33724100327154	0.313591216713968	0.645255447475314
GO:0050145	nucleoside monophosphate kinase activity	5/3668	19/18639	0.263157894736842	1.33724100327154	0.313591216713968	0.645255447475314
GO:0140036	ubiquitin-modified protein reader activity	5/3668	19/18639	0.263157894736842	1.33724100327154	0.313591216713968	0.645255447475314
GO:0140767	enzyme-substrate adaptor activity	30/3668	139/18639	0.215827338129496	1.09673003146011	0.316985313792623	0.651224882612839
GO:0033192	calmodulin-dependent protein phosphatase activity	18/3668	81/18639	0.222222222222222	1.12922573609596	0.323014505764284	0.65545647022215
GO:0140791	histone H2AXS140 phosphatase activity	18/3668	81/18639	0.222222222222222	1.12922573609596	0.323014505764284	0.65545647022215
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	18/3668	81/18639	0.222222222222222	1.12922573609596	0.323014505764284	0.65545647022215
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	18/3668	81/18639	0.222222222222222	1.12922573609596	0.323014505764284	0.65545647022215
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	18/3668	81/18639	0.222222222222222	1.12922573609596	0.323014505764284	0.65545647022215
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	18/3668	81/18639	0.222222222222222	1.12922573609596	0.323014505764284	0.65545647022215
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	18/3668	81/18639	0.222222222222222	1.12922573609596	0.323014505764284	0.65545647022215
GO:1990439	MAP kinase serine/threonine phosphatase activity	18/3668	81/18639	0.222222222222222	1.12922573609596	0.323014505764284	0.65545647022215
GO:0005109	frizzled binding	9/3668	38/18639	0.236842105263158	1.20351690294438	0.326042973261836	0.660587066992155
GO:0072341	modified amino acid binding	20/3668	91/18639	0.21978021978022	1.11681666207293	0.329148597069048	0.662125550935404
GO:0005315	phosphate transmembrane transporter activity	6/3668	24/18639	0.25	1.27037895310796	0.329176598463282	0.662125550935404
GO:0060229	lipase activator activity	6/3668	24/18639	0.25	1.27037895310796	0.329176598463282	0.662125550935404
GO:0070300	phosphatidic acid binding	6/3668	24/18639	0.25	1.27037895310796	0.329176598463282	0.662125550935404
GO:0015179	L-amino acid transmembrane transporter activity	14/3668	62/18639	0.225806451612903	1.14743905442009	0.329308468557578	0.662125550935404
GO:0004712	protein serine/threonine/tyrosine kinase activity	10/3668	43/18639	0.232558139534884	1.18174786335624	0.333361416303283	0.668478555943253
GO:0016500	protein-hormone receptor activity	15/3668	67/18639	0.223880597014925	1.13765279382802	0.333495236323641	0.668478555943253
GO:0051015	actin filament binding	44/3668	209/18639	0.210526315789474	1.06979280261723	0.333986258079142	0.668478555943253
GO:0000149	SNARE binding	23/3668	106/18639	0.216981132075472	1.10259305364087	0.33647632863304	0.669966717262571
GO:1902936	phosphatidylinositol bisphosphate binding	24/3668	111/18639	0.216216216216216	1.09870612160688	0.338531778743692	0.669966717262571
GO:0015103	inorganic anion transmembrane transporter activity	35/3668	165/18639	0.212121212121212	1.07789729354615	0.338929956960643	0.669966717262571
GO:0004129	cytochrome-c oxidase activity	4/3668	15/18639	0.266666666666667	1.35507088331516	0.33980143873272	0.669966717262571
GO:0004698	calcium,diacylglycerol-dependent serine/threonine kinase activity	4/3668	15/18639	0.266666666666667	1.35507088331516	0.33980143873272	0.669966717262571
GO:0004699	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	4/3668	15/18639	0.266666666666667	1.35507088331516	0.33980143873272	0.669966717262571
GO:0005402	carbohydrate:monoatomic cation symporter activity	4/3668	15/18639	0.266666666666667	1.35507088331516	0.33980143873272	0.669966717262571
GO:0047372	monoacylglycerol lipase activity	4/3668	15/18639	0.266666666666667	1.35507088331516	0.33980143873272	0.669966717262571
GO:0141050	histone H3K deacetylase activity	4/3668	15/18639	0.266666666666667	1.35507088331516	0.33980143873272	0.669966717262571
GO:0141051	histone H4K deacetylase activity	4/3668	15/18639	0.266666666666667	1.35507088331516	0.33980143873272	0.669966717262571
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	18/3668	82/18639	0.219512195121951	1.11545469053382	0.343461865396344	0.675168339566325
GO:0033549	MAP kinase phosphatase activity	18/3668	82/18639	0.219512195121951	1.11545469053382	0.343461865396344	0.675168339566325
GO:0016831	carboxy-lyase activity	8/3668	34/18639	0.235294117647059	1.19565077939573	0.349344327854049	0.681458338179842
GO:0016891	RNA endonuclease activity, producing 5'-phosphomonoesters	8/3668	34/18639	0.235294117647059	1.19565077939573	0.349344327854049	0.681458338179842
GO:0030332	cyclin binding	8/3668	34/18639	0.235294117647059	1.19565077939573	0.349344327854049	0.681458338179842
GO:0005507	copper ion binding	14/3668	63/18639	0.222222222222222	1.12922573609596	0.352902618692213	0.681458338179842
GO:1901681	sulfur compound binding	57/3668	275/18639	0.207272727272727	1.05325964112224	0.353115851889402	0.681458338179842
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	9/3668	39/18639	0.230769230769231	1.17265749517658	0.356286391012967	0.681458338179842
GO:0000339	RNA cap binding	5/3668	20/18639	0.25	1.27037895310796	0.356351204082431	0.681458338179842
GO:0005326	neurotransmitter transmembrane transporter activity	5/3668	20/18639	0.25	1.27037895310796	0.356351204082431	0.681458338179842
GO:0016408	C-acyltransferase activity	5/3668	20/18639	0.25	1.27037895310796	0.356351204082431	0.681458338179842
GO:0016505	peptidase activator activity involved in apoptotic process	5/3668	20/18639	0.25	1.27037895310796	0.356351204082431	0.681458338179842
GO:0042288	MHC class I protein binding	5/3668	20/18639	0.25	1.27037895310796	0.356351204082431	0.681458338179842
GO:0043024	ribosomal small subunit binding	5/3668	20/18639	0.25	1.27037895310796	0.356351204082431	0.681458338179842
GO:0140939	histone H4 methyltransferase activity	5/3668	20/18639	0.25	1.27037895310796	0.356351204082431	0.681458338179842
GO:0005004	GPI-linked ephrin receptor activity	11/3668	49/18639	0.224489795918367	1.14074844768878	0.366606758813216	0.681458338179842
GO:0005008	hepatocyte growth factor receptor activity	11/3668	49/18639	0.224489795918367	1.14074844768878	0.366606758813216	0.681458338179842
GO:0005009	insulin receptor activity	11/3668	49/18639	0.224489795918367	1.14074844768878	0.366606758813216	0.681458338179842
GO:0005011	macrophage colony-stimulating factor receptor activity	11/3668	49/18639	0.224489795918367	1.14074844768878	0.366606758813216	0.681458338179842
GO:0005018	platelet-derived growth factor alpha-receptor activity	11/3668	49/18639	0.224489795918367	1.14074844768878	0.366606758813216	0.681458338179842
GO:0005020	stem cell factor receptor activity	11/3668	49/18639	0.224489795918367	1.14074844768878	0.366606758813216	0.681458338179842
GO:0008288	boss receptor activity	11/3668	49/18639	0.224489795918367	1.14074844768878	0.366606758813216	0.681458338179842
GO:0036332	placental growth factor receptor activity	11/3668	49/18639	0.224489795918367	1.14074844768878	0.366606758813216	0.681458338179842
GO:0038062	protein tyrosine kinase collagen receptor activity	11/3668	49/18639	0.224489795918367	1.14074844768878	0.366606758813216	0.681458338179842
GO:0060175	brain-derived neurotrophic factor receptor activity	11/3668	49/18639	0.224489795918367	1.14074844768878	0.366606758813216	0.681458338179842
GO:0004709	MAP kinase kinase kinase activity	6/3668	25/18639	0.24	1.21956379498364	0.367587952561176	0.681458338179842
GO:0017025	TBP-class protein binding	6/3668	25/18639	0.24	1.21956379498364	0.367587952561176	0.681458338179842
GO:0047617	fatty acyl-CoA hydrolase activity	6/3668	25/18639	0.24	1.21956379498364	0.367587952561176	0.681458338179842
GO:0120020	cholesterol transfer activity	6/3668	25/18639	0.24	1.21956379498364	0.367587952561176	0.681458338179842
GO:0003925	G protein activity	12/3668	54/18639	0.222222222222222	1.12922573609596	0.370542679733317	0.681458338179842
GO:0004722	protein serine/threonine phosphatase activity	22/3668	103/18639	0.213592233009709	1.08537230945146	0.371413329723653	0.681458338179842
GO:0001161	intronic transcription regulatory region sequence-specific DNA binding	3/3668	11/18639	0.272727272727273	1.38586794884505	0.371939032420641	0.681458338179842
GO:0004016	adenylate cyclase activity	3/3668	11/18639	0.272727272727273	1.38586794884505	0.371939032420641	0.681458338179842
GO:0005114	type II transforming growth factor beta receptor binding	3/3668	11/18639	0.272727272727273	1.38586794884505	0.371939032420641	0.681458338179842
GO:0005225	volume-sensitive anion channel activity	3/3668	11/18639	0.272727272727273	1.38586794884505	0.371939032420641	0.681458338179842
GO:0008046	axon guidance receptor activity	3/3668	11/18639	0.272727272727273	1.38586794884505	0.371939032420641	0.681458338179842
GO:0008271	secondary active sulfate transmembrane transporter activity	3/3668	11/18639	0.272727272727273	1.38586794884505	0.371939032420641	0.681458338179842
GO:0015173	aromatic amino acid transmembrane transporter activity	3/3668	11/18639	0.272727272727273	1.38586794884505	0.371939032420641	0.681458338179842
GO:0016653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	3/3668	11/18639	0.272727272727273	1.38586794884505	0.371939032420641	0.681458338179842
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	3/3668	11/18639	0.272727272727273	1.38586794884505	0.371939032420641	0.681458338179842
GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives	3/3668	11/18639	0.272727272727273	1.38586794884505	0.371939032420641	0.681458338179842
GO:0019107	myristoyltransferase activity	3/3668	11/18639	0.272727272727273	1.38586794884505	0.371939032420641	0.681458338179842
GO:0032129	histone H3K9 deacetylase activity, hydrolytic mechanism	3/3668	11/18639	0.272727272727273	1.38586794884505	0.371939032420641	0.681458338179842
GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding	3/3668	11/18639	0.272727272727273	1.38586794884505	0.371939032420641	0.681458338179842
GO:0042608	T cell receptor binding	3/3668	11/18639	0.272727272727273	1.38586794884505	0.371939032420641	0.681458338179842
GO:0048407	platelet-derived growth factor binding	3/3668	11/18639	0.272727272727273	1.38586794884505	0.371939032420641	0.681458338179842
GO:0050998	nitric-oxide synthase binding	3/3668	11/18639	0.272727272727273	1.38586794884505	0.371939032420641	0.681458338179842
GO:0070990	snRNP binding	3/3668	11/18639	0.272727272727273	1.38586794884505	0.371939032420641	0.681458338179842
GO:0140937	histone H4K12 deacetylase activity, hydrolytic mechanism	3/3668	11/18639	0.272727272727273	1.38586794884505	0.371939032420641	0.681458338179842
GO:0180030	inositol phosphate kinase activity	3/3668	11/18639	0.272727272727273	1.38586794884505	0.371939032420641	0.681458338179842
GO:1900750	oligopeptide binding	3/3668	11/18639	0.272727272727273	1.38586794884505	0.371939032420641	0.681458338179842
GO:0031593	polyubiquitin modification-dependent protein binding	13/3668	59/18639	0.220338983050847	1.11965602646803	0.373896405098903	0.683149586632989
GO:0036002	pre-mRNA binding	13/3668	59/18639	0.220338983050847	1.11965602646803	0.373896405098903	0.683149586632989
GO:0001965	G-protein alpha-subunit binding	7/3668	30/18639	0.233333333333333	1.18568702290076	0.375755263202279	0.684652003710635
GO:0001968	fibronectin binding	7/3668	30/18639	0.233333333333333	1.18568702290076	0.375755263202279	0.684652003710635
GO:0048029	monosaccharide binding	16/3668	74/18639	0.216216216216216	1.09870612160688	0.381482119773739	0.694057425705106
GO:0034061	DNA polymerase activity	8/3668	35/18639	0.228571428571429	1.16148932855585	0.381968015509169	0.694057425705106
GO:0046943	carboxylic acid transmembrane transporter activity	39/3668	188/18639	0.207446808510638	1.05414423768533	0.384422866506974	0.696339086403014
GO:0017018	myosin phosphatase activity	18/3668	84/18639	0.214285714285714	1.08889624552111	0.385116302064115	0.696339086403014
GO:0015144	carbohydrate transmembrane transporter activity	9/3668	40/18639	0.225	1.14334105779716	0.386849709223452	0.696339086403014
GO:0050997	quaternary ammonium group binding	9/3668	40/18639	0.225	1.14334105779716	0.386849709223452	0.696339086403014
GO:0004708	MAP kinase kinase activity	4/3668	16/18639	0.25	1.27037895310796	0.389022139110843	0.696339086403014
GO:0008296	3'-5'-DNA exonuclease activity	4/3668	16/18639	0.25	1.27037895310796	0.389022139110843	0.696339086403014
GO:0016675	oxidoreductase activity, acting on a heme group of donors	4/3668	16/18639	0.25	1.27037895310796	0.389022139110843	0.696339086403014
GO:0017070	U6 snRNA binding	4/3668	16/18639	0.25	1.27037895310796	0.389022139110843	0.696339086403014
GO:0030275	LRR domain binding	4/3668	16/18639	0.25	1.27037895310796	0.389022139110843	0.696339086403014
GO:0070411	I-SMAD binding	4/3668	16/18639	0.25	1.27037895310796	0.389022139110843	0.696339086403014
GO:0097027	ubiquitin-protein transferase activator activity	4/3668	16/18639	0.25	1.27037895310796	0.389022139110843	0.696339086403014
GO:0005007	fibroblast growth factor receptor activity	11/3668	50/18639	0.22	1.11793347873501	0.394001442865971	0.703345818953983
GO:0032813	tumor necrosis factor receptor superfamily binding	11/3668	50/18639	0.22	1.11793347873501	0.394001442865971	0.703345818953983
GO:0140101	catalytic activity, acting on a tRNA	29/3668	139/18639	0.20863309352518	1.06017236374477	0.395386178265472	0.704865238176368
GO:0005342	organic acid transmembrane transporter activity	39/3668	189/18639	0.206349206349206	1.04856675494625	0.398477013430571	0.707046181179722
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	5/3668	21/18639	0.238095238095238	1.20988471724568	0.399285731385369	0.707046181179722
GO:0010314	phosphatidylinositol-5-phosphate binding	5/3668	21/18639	0.238095238095238	1.20988471724568	0.399285731385369	0.707046181179722
GO:0015174	basic amino acid transmembrane transporter activity	5/3668	21/18639	0.238095238095238	1.20988471724568	0.399285731385369	0.707046181179722
GO:0035613	RNA stem-loop binding	5/3668	21/18639	0.238095238095238	1.20988471724568	0.399285731385369	0.707046181179722
GO:0015145	monosaccharide transmembrane transporter activity	6/3668	26/18639	0.230769230769231	1.17265749517658	0.406156138232693	0.714977994248542
GO:0016289	acyl-CoA hydrolase activity	6/3668	26/18639	0.230769230769231	1.17265749517658	0.406156138232693	0.714977994248542
GO:0030507	spectrin binding	6/3668	26/18639	0.230769230769231	1.17265749517658	0.406156138232693	0.714977994248542
GO:0043548	phosphatidylinositol 3-kinase binding	6/3668	26/18639	0.230769230769231	1.17265749517658	0.406156138232693	0.714977994248542
GO:0015631	tubulin binding	78/3668	385/18639	0.202597402597403	1.02950190485632	0.406471213989898	0.714977994248542
GO:0016829	lyase activity	41/3668	200/18639	0.205	1.04171074154853	0.412537675148013	0.723868984661519
GO:0015078	proton transmembrane transporter activity	38/3668	185/18639	0.205405405405405	1.04377081552654	0.412621760371025	0.723868984661519
GO:0004033	aldo-keto reductase (NADPH) activity	8/3668	36/18639	0.222222222222222	1.12922573609596	0.414724975592894	0.726593756973757
GO:0042169	SH2 domain binding	9/3668	41/18639	0.219512195121951	1.11545469053382	0.417537916523888	0.730553096328551
GO:0008017	microtubule binding	56/3668	276/18639	0.202898550724638	1.03103219382675	0.422599109583072	0.734367083239051
GO:0140299	molecular sensor activity	15/3668	71/18639	0.211267605633803	1.07355967868278	0.425800348935716	0.734367083239051
GO:0030971	receptor tyrosine kinase binding	17/3668	81/18639	0.209876543209877	1.06649097297952	0.42694824995814	0.734367083239051
GO:0016779	nucleotidyltransferase activity	28/3668	136/18639	0.205882352941176	1.04619443197126	0.428437050965929	0.734367083239051
GO:0000340	RNA 7-methylguanosine cap binding	3/3668	12/18639	0.25	1.27037895310796	0.430280183517809	0.734367083239051
GO:0004526	ribonuclease P activity	3/3668	12/18639	0.25	1.27037895310796	0.430280183517809	0.734367083239051
GO:0005436	sodium:phosphate symporter activity	3/3668	12/18639	0.25	1.27037895310796	0.430280183517809	0.734367083239051
GO:0008504	monoamine transmembrane transporter activity	3/3668	12/18639	0.25	1.27037895310796	0.430280183517809	0.734367083239051
GO:0016208	AMP binding	3/3668	12/18639	0.25	1.27037895310796	0.430280183517809	0.734367083239051
GO:0016273	arginine N-methyltransferase activity	3/3668	12/18639	0.25	1.27037895310796	0.430280183517809	0.734367083239051
GO:0016274	protein-arginine N-methyltransferase activity	3/3668	12/18639	0.25	1.27037895310796	0.430280183517809	0.734367083239051
GO:0035259	nuclear glucocorticoid receptor binding	3/3668	12/18639	0.25	1.27037895310796	0.430280183517809	0.734367083239051
GO:0042301	phosphate ion binding	3/3668	12/18639	0.25	1.27037895310796	0.430280183517809	0.734367083239051
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	3/3668	12/18639	0.25	1.27037895310796	0.430280183517809	0.734367083239051
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	3/3668	12/18639	0.25	1.27037895310796	0.430280183517809	0.734367083239051
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	3/3668	12/18639	0.25	1.27037895310796	0.430280183517809	0.734367083239051
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	3/3668	12/18639	0.25	1.27037895310796	0.430280183517809	0.734367083239051
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	3/3668	12/18639	0.25	1.27037895310796	0.430280183517809	0.734367083239051
GO:0141221	histone deacetylase activity, hydrolytic mechanism	3/3668	12/18639	0.25	1.27037895310796	0.430280183517809	0.734367083239051
GO:0004659	prenyltransferase activity	4/3668	17/18639	0.235294117647059	1.19565077939573	0.437682725529217	0.742206521725412
GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process	4/3668	17/18639	0.235294117647059	1.19565077939573	0.437682725529217	0.742206521725412
GO:0016805	dipeptidase activity	4/3668	17/18639	0.235294117647059	1.19565077939573	0.437682725529217	0.742206521725412
GO:0017110	nucleoside diphosphate phosphatase activity	4/3668	17/18639	0.235294117647059	1.19565077939573	0.437682725529217	0.742206521725412
GO:0048038	quinone binding	4/3668	17/18639	0.235294117647059	1.19565077939573	0.437682725529217	0.742206521725412
GO:0008970	phospholipase A1 activity	5/3668	22/18639	0.227272727272727	1.15488995737087	0.441887776756151	0.747418377842349
GO:0015377	chloride:monoatomic cation symporter activity	5/3668	22/18639	0.227272727272727	1.15488995737087	0.441887776756151	0.747418377842349
GO:1990756	ubiquitin-like ligase-substrate adaptor activity	25/3668	122/18639	0.204918032786885	1.04129422385898	0.44639486473261	0.754076235692811
GO:0140223	general transcription initiation factor activity	14/3668	68/18639	0.205882352941176	1.04619443197126	0.473303072923956	0.796700571900082
GO:0005003	ephrin receptor activity	11/3668	53/18639	0.207547169811321	1.0546542252217	0.47632506255583	0.796700571900082
GO:0005005	transmembrane-ephrin receptor activity	11/3668	53/18639	0.207547169811321	1.0546542252217	0.47632506255583	0.796700571900082
GO:0038064	collagen receptor activity	11/3668	53/18639	0.207547169811321	1.0546542252217	0.47632506255583	0.796700571900082
GO:0019955	cytokine binding	29/3668	144/18639	0.201388888888889	1.02336082333697	0.478040700927728	0.796700571900082
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	9/3668	43/18639	0.209302325581395	1.06357307702062	0.478553388155681	0.796700571900082
GO:0000146	microfilament motor activity	8/3668	38/18639	0.210526315789474	1.06979280261723	0.479747293914508	0.796700571900082
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	7/3668	33/18639	0.212121212121212	1.07789729354615	0.481002506575986	0.796700571900082
GO:0051119	sugar transmembrane transporter activity	6/3668	28/18639	0.214285714285714	1.08889624552111	0.482324188826172	0.796700571900082
GO:0000295	adenine nucleotide transmembrane transporter activity	5/3668	23/18639	0.217391304347826	1.10467735052866	0.483712040429265	0.796700571900082
GO:0004602	glutathione peroxidase activity	5/3668	23/18639	0.217391304347826	1.10467735052866	0.483712040429265	0.796700571900082
GO:0017134	fibroblast growth factor binding	5/3668	23/18639	0.217391304347826	1.10467735052866	0.483712040429265	0.796700571900082
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	4/3668	18/18639	0.222222222222222	1.12922573609596	0.485144659485913	0.796700571900082
GO:0004706	JUN kinase kinase kinase activity	4/3668	18/18639	0.222222222222222	1.12922573609596	0.485144659485913	0.796700571900082
GO:0016854	racemase and epimerase activity	4/3668	18/18639	0.222222222222222	1.12922573609596	0.485144659485913	0.796700571900082
GO:0098641	cadherin binding involved in cell-cell adhesion	4/3668	18/18639	0.222222222222222	1.12922573609596	0.485144659485913	0.796700571900082
GO:1901611	phosphatidylglycerol binding	4/3668	18/18639	0.222222222222222	1.12922573609596	0.485144659485913	0.796700571900082
GO:0002161	aminoacyl-tRNA editing activity	3/3668	13/18639	0.230769230769231	1.17265749517658	0.486514701328459	0.796700571900082
GO:0005542	folic acid binding	3/3668	13/18639	0.230769230769231	1.17265749517658	0.486514701328459	0.796700571900082
GO:0008035	high-density lipoprotein particle binding	3/3668	13/18639	0.230769230769231	1.17265749517658	0.486514701328459	0.796700571900082
GO:0009982	pseudouridine synthase activity	3/3668	13/18639	0.230769230769231	1.17265749517658	0.486514701328459	0.796700571900082
GO:0070700	BMP receptor binding	3/3668	13/18639	0.230769230769231	1.17265749517658	0.486514701328459	0.796700571900082
GO:0140410	monoatomic cation:bicarbonate symporter activity	3/3668	13/18639	0.230769230769231	1.17265749517658	0.486514701328459	0.796700571900082
GO:0140852	histone ubiquitin ligase activity	3/3668	13/18639	0.230769230769231	1.17265749517658	0.486514701328459	0.796700571900082
GO:0016853	isomerase activity	36/3668	180/18639	0.2	1.01630316248637	0.486705042788317	0.796700571900082
GO:0015370	solute:sodium symporter activity	16/3668	79/18639	0.20253164556962	1.02916775947987	0.493816747182673	0.807341488896424
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	36/3668	181/18639	0.198895027624309	1.010688227887	0.501479490061631	0.818855879321897
GO:0035401	histone H3Y41 kinase activity	23/3668	115/18639	0.2	1.01630316248637	0.502864149734114	0.818931616827609
GO:0140801	histone H2AXY142 kinase activity	23/3668	115/18639	0.2	1.01630316248637	0.502864149734114	0.818931616827609
GO:0017069	snRNA binding	11/3668	54/18639	0.203703703703704	1.0351235914213	0.503385672115078	0.818931616827609
GO:0003954	NADH dehydrogenase activity	9/3668	44/18639	0.204545454545455	1.03940096163379	0.508542314118305	0.825287956941377
GO:0019205	nucleobase-containing compound kinase activity	9/3668	44/18639	0.204545454545455	1.03940096163379	0.508542314118305	0.825287956941377
GO:0015020	glucuronosyltransferase activity	7/3668	34/18639	0.205882352941176	1.04619443197126	0.51513610846686	0.834962943907634
GO:0003785	actin monomer binding	6/3668	29/18639	0.206896551724138	1.05134809912383	0.519298405918208	0.837598527738648
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	6/3668	29/18639	0.206896551724138	1.05134809912383	0.519298405918208	0.837598527738648
GO:0097472	cyclin-dependent protein kinase activity	6/3668	29/18639	0.206896551724138	1.05134809912383	0.519298405918208	0.837598527738648
GO:0099604	ligand-gated calcium channel activity	6/3668	29/18639	0.206896551724138	1.05134809912383	0.519298405918208	0.837598527738648
GO:0097110	scaffold protein binding	14/3668	70/18639	0.2	1.01630316248637	0.520917626842627	0.8391855915355
GO:0004622	lysophospholipase activity	5/3668	24/18639	0.208333333333333	1.05864912758997	0.52437926199926	0.839642430425482
GO:0015149	hexose transmembrane transporter activity	5/3668	24/18639	0.208333333333333	1.05864912758997	0.52437926199926	0.839642430425482
GO:0030552	cAMP binding	5/3668	24/18639	0.208333333333333	1.05864912758997	0.52437926199926	0.839642430425482
GO:0048027	mRNA 5'-UTR binding	5/3668	24/18639	0.208333333333333	1.05864912758997	0.52437926199926	0.839642430425482
GO:0055056	D-glucose transmembrane transporter activity	5/3668	24/18639	0.208333333333333	1.05864912758997	0.52437926199926	0.839642430425482
GO:0017171	serine hydrolase activity	39/3668	198/18639	0.196969696969697	1.00090462972142	0.526207162600349	0.841549227354796
GO:0030246	carbohydrate binding	55/3668	280/18639	0.196428571428571	0.998154891727683	0.530416275531962	0.84495018629079
GO:0030506	ankyrin binding	4/3668	19/18639	0.210526315789474	1.06979280261723	0.530892244225099	0.84495018629079
GO:0031420	alkali metal ion binding	4/3668	19/18639	0.210526315789474	1.06979280261723	0.530892244225099	0.84495018629079
GO:0097001	ceramide binding	4/3668	19/18639	0.210526315789474	1.06979280261723	0.530892244225099	0.84495018629079
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	17/3668	86/18639	0.197674418604651	1.00448568385281	0.535060563339568	0.850063783335428
GO:0004715	non-membrane spanning protein tyrosine kinase activity	9/3668	45/18639	0.2	1.01630316248637	0.537983087205188	0.850063783335428
GO:0008494	translation activator activity	3/3668	14/18639	0.214285714285714	1.08889624552111	0.539896679953387	0.850063783335428
GO:0015386	potassium:proton antiporter activity	3/3668	14/18639	0.214285714285714	1.08889624552111	0.539896679953387	0.850063783335428
GO:0016530	metallochaperone activity	3/3668	14/18639	0.214285714285714	1.08889624552111	0.539896679953387	0.850063783335428
GO:0019992	diacylglycerol binding	3/3668	14/18639	0.214285714285714	1.08889624552111	0.539896679953387	0.850063783335428
GO:0031404	chloride ion binding	3/3668	14/18639	0.214285714285714	1.08889624552111	0.539896679953387	0.850063783335428
GO:0034236	protein kinase A catalytic subunit binding	3/3668	14/18639	0.214285714285714	1.08889624552111	0.539896679953387	0.850063783335428
GO:0044548	S100 protein binding	3/3668	14/18639	0.214285714285714	1.08889624552111	0.539896679953387	0.850063783335428
GO:0051536	iron-sulfur cluster binding	15/3668	76/18639	0.197368421052632	1.00293075245365	0.54096569524794	0.850576367355192
GO:0008236	serine-type peptidase activity	38/3668	194/18639	0.195876288659794	0.995348458105206	0.541871451429245	0.850576367355192
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	8/3668	40/18639	0.2	1.01630316248637	0.542797787797447	0.850576367355192
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	8/3668	40/18639	0.2	1.01630316248637	0.542797787797447	0.850576367355192
GO:0005154	epidermal growth factor receptor binding	7/3668	35/18639	0.2	1.01630316248637	0.548428131706283	0.857365162111242
GO:0061631	ubiquitin conjugating enzyme activity	7/3668	35/18639	0.2	1.01630316248637	0.548428131706283	0.857365162111242
GO:0043178	alcohol binding	18/3668	92/18639	0.195652173913043	0.994209615475795	0.552861933840753	0.861436678320976
GO:0052689	carboxylic ester hydrolase activity	18/3668	92/18639	0.195652173913043	0.994209615475795	0.552861933840753	0.861436678320976
GO:0015215	nucleotide transmembrane transporter activity	6/3668	30/18639	0.2	1.01630316248637	0.55518419159719	0.861436678320976
GO:0035925	mRNA 3'-UTR AU-rich region binding	6/3668	30/18639	0.2	1.01630316248637	0.55518419159719	0.861436678320976
GO:0051721	protein phosphatase 2A binding	6/3668	30/18639	0.2	1.01630316248637	0.55518419159719	0.861436678320976
GO:0098918	structural constituent of synapse	6/3668	30/18639	0.2	1.01630316248637	0.55518419159719	0.861436678320976
GO:0008081	phosphoric diester hydrolase activity	17/3668	87/18639	0.195402298850575	0.992939871394728	0.556068067459479	0.861436678320976
GO:0170055	lipid transmembrane transporter activity	11/3668	56/18639	0.196428571428571	0.998154891727683	0.556249422110365	0.861436678320976
GO:0008509	monoatomic anion transmembrane transporter activity	29/3668	149/18639	0.194630872483221	0.989019856110896	0.559541259958568	0.865519911481579
GO:0051540	metal cluster binding	15/3668	77/18639	0.194805194805195	0.989905677746463	0.563222364772143	0.868711009385006
GO:0015296	monoatomic anion:monoatomic cation symporter activity	5/3668	25/18639	0.2	1.01630316248637	0.563577089358782	0.868711009385006
GO:0019211	phosphatase activator activity	5/3668	25/18639	0.2	1.01630316248637	0.563577089358782	0.868711009385006
GO:0004180	carboxypeptidase activity	9/3668	46/18639	0.195652173913043	0.994209615475795	0.566743320195729	0.871557538973875
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	9/3668	46/18639	0.195652173913043	0.994209615475795	0.566743320195729	0.871557538973875
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	8/3668	41/18639	0.195121951219512	0.991515280474506	0.573163817197096	0.87633032698769
GO:0008137	NADH dehydrogenase (ubiquinone) activity	8/3668	41/18639	0.195121951219512	0.991515280474506	0.573163817197096	0.87633032698769
GO:0015175	neutral L-amino acid transmembrane transporter activity	8/3668	41/18639	0.195121951219512	0.991515280474506	0.573163817197096	0.87633032698769
GO:0017080	sodium channel regulator activity	8/3668	41/18639	0.195121951219512	0.991515280474506	0.573163817197096	0.87633032698769
GO:0061650	ubiquitin-like protein conjugating enzyme activity	8/3668	41/18639	0.195121951219512	0.991515280474506	0.573163817197096	0.87633032698769
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	4/3668	20/18639	0.2	1.01630316248637	0.574527504260766	0.876386643335417
GO:0030742	GTP-dependent protein binding	4/3668	20/18639	0.2	1.01630316248637	0.574527504260766	0.876386643335417
GO:0016651	oxidoreductase activity, acting on NAD(P)H	17/3668	88/18639	0.193181818181818	0.981656463765242	0.576743758811613	0.878752601372711
GO:0005310	dicarboxylic acid transmembrane transporter activity	6/3668	31/18639	0.193548387096774	0.983519189502937	0.589772928565996	0.888580350777137
GO:0005452	solute:inorganic anion antiporter activity	6/3668	31/18639	0.193548387096774	0.983519189502937	0.589772928565996	0.888580350777137
GO:0008242	omega peptidase activity	3/3668	15/18639	0.2	1.01630316248637	0.589920490258554	0.888580350777137
GO:0010181	FMN binding	3/3668	15/18639	0.2	1.01630316248637	0.589920490258554	0.888580350777137
GO:0015116	sulfate transmembrane transporter activity	3/3668	15/18639	0.2	1.01630316248637	0.589920490258554	0.888580350777137
GO:0015556	C4-dicarboxylate transmembrane transporter activity	3/3668	15/18639	0.2	1.01630316248637	0.589920490258554	0.888580350777137
GO:0033130	acetylcholine receptor binding	3/3668	15/18639	0.2	1.01630316248637	0.589920490258554	0.888580350777137
GO:0034483	heparan sulfate sulfotransferase activity	3/3668	15/18639	0.2	1.01630316248637	0.589920490258554	0.888580350777137
GO:0050780	dopamine receptor binding	3/3668	15/18639	0.2	1.01630316248637	0.589920490258554	0.888580350777137
GO:0051371	muscle alpha-actinin binding	3/3668	15/18639	0.2	1.01630316248637	0.589920490258554	0.888580350777137
GO:0005112	Notch binding	5/3668	26/18639	0.192307692307692	0.977214579313816	0.601058268198327	0.89682480647627
GO:0005227	calcium-activated cation channel activity	5/3668	26/18639	0.192307692307692	0.977214579313816	0.601058268198327	0.89682480647627
GO:0008157	protein phosphatase 1 binding	5/3668	26/18639	0.192307692307692	0.977214579313816	0.601058268198327	0.89682480647627
GO:0015216	purine nucleotide transmembrane transporter activity	5/3668	26/18639	0.192307692307692	0.977214579313816	0.601058268198327	0.89682480647627
GO:0016859	cis-trans isomerase activity	8/3668	42/18639	0.19047619047619	0.967907773796541	0.602575451645537	0.89682480647627
GO:0015085	calcium ion transmembrane transporter activity	28/3668	147/18639	0.19047619047619	0.967907773796541	0.609588339455695	0.89682480647627
GO:0043394	proteoglycan binding	7/3668	37/18639	0.189189189189189	0.961367856406024	0.611807631462292	0.89682480647627
GO:0017046	peptide hormone binding	10/3668	53/18639	0.188679245283019	0.958776568383367	0.613817815226191	0.89682480647627
GO:0001094	TFIID-class transcription factor complex binding	2/3668	10/18639	0.2	1.01630316248637	0.614487528768962	0.89682480647627
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	2/3668	10/18639	0.2	1.01630316248637	0.614487528768962	0.89682480647627
GO:0008190	eukaryotic initiation factor 4E binding	2/3668	10/18639	0.2	1.01630316248637	0.614487528768962	0.89682480647627
GO:0008641	ubiquitin-like modifier activating enzyme activity	2/3668	10/18639	0.2	1.01630316248637	0.614487528768962	0.89682480647627
GO:0015203	polyamine transmembrane transporter activity	2/3668	10/18639	0.2	1.01630316248637	0.614487528768962	0.89682480647627
GO:0015279	store-operated calcium channel activity	2/3668	10/18639	0.2	1.01630316248637	0.614487528768962	0.89682480647627
GO:0016175	superoxide-generating NAD(P)H oxidase activity	2/3668	10/18639	0.2	1.01630316248637	0.614487528768962	0.89682480647627
GO:0016783	sulfurtransferase activity	2/3668	10/18639	0.2	1.01630316248637	0.614487528768962	0.89682480647627
GO:0019911	structural constituent of myelin sheath	2/3668	10/18639	0.2	1.01630316248637	0.614487528768962	0.89682480647627
GO:0032356	oxidized DNA binding	2/3668	10/18639	0.2	1.01630316248637	0.614487528768962	0.89682480647627
GO:0033204	ribonuclease P RNA binding	2/3668	10/18639	0.2	1.01630316248637	0.614487528768962	0.89682480647627
GO:0035256	G protein-coupled glutamate receptor binding	2/3668	10/18639	0.2	1.01630316248637	0.614487528768962	0.89682480647627
GO:0035374	chondroitin sulfate binding	2/3668	10/18639	0.2	1.01630316248637	0.614487528768962	0.89682480647627
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	2/3668	10/18639	0.2	1.01630316248637	0.614487528768962	0.89682480647627
GO:0043422	protein kinase B binding	2/3668	10/18639	0.2	1.01630316248637	0.614487528768962	0.89682480647627
GO:0050815	phosphoserine residue binding	2/3668	10/18639	0.2	1.01630316248637	0.614487528768962	0.89682480647627
GO:0140940	histone H2A methyltransferase activity	2/3668	10/18639	0.2	1.01630316248637	0.614487528768962	0.89682480647627
GO:1990259	histone H2AQ104 methyltransferase activity	2/3668	10/18639	0.2	1.01630316248637	0.614487528768962	0.89682480647627
GO:1990757	ubiquitin ligase activator activity	2/3668	10/18639	0.2	1.01630316248637	0.614487528768962	0.89682480647627
GO:1990763	arrestin family protein binding	2/3668	10/18639	0.2	1.01630316248637	0.614487528768962	0.89682480647627
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	4/3668	21/18639	0.19047619047619	0.967907773796541	0.615760862584389	0.89682480647627
GO:0072542	protein phosphatase activator activity	4/3668	21/18639	0.19047619047619	0.967907773796541	0.615760862584389	0.89682480647627
GO:0016879	ligase activity, forming carbon-nitrogen bonds	9/3668	48/18639	0.1875	0.952784214830971	0.621774396002572	0.903235348236374
GO:0015106	bicarbonate transmembrane transporter activity	6/3668	32/18639	0.1875	0.952784214830971	0.622897352190262	0.903235348236374
GO:0071813	lipoprotein particle binding	6/3668	32/18639	0.1875	0.952784214830971	0.622897352190262	0.903235348236374
GO:0071814	protein-lipid complex binding	6/3668	32/18639	0.1875	0.952784214830971	0.622897352190262	0.903235348236374
GO:0000049	tRNA binding	15/3668	80/18639	0.1875	0.952784214830971	0.627337508858477	0.908676369739088
GO:0001786	phosphatidylserine binding	11/3668	59/18639	0.186440677966102	0.947401253165259	0.631008079214174	0.912991974416127
GO:0004707	MAP kinase activity	3/3668	16/18639	0.1875	0.952784214830971	0.636281648215718	0.915122185794415
GO:0015385	sodium:proton antiporter activity	3/3668	16/18639	0.1875	0.952784214830971	0.636281648215718	0.915122185794415
GO:0022858	alanine transmembrane transporter activity	3/3668	16/18639	0.1875	0.952784214830971	0.636281648215718	0.915122185794415
GO:0043023	ribosomal large subunit binding	3/3668	16/18639	0.1875	0.952784214830971	0.636281648215718	0.915122185794415
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	3/3668	16/18639	0.1875	0.952784214830971	0.636281648215718	0.915122185794415
GO:0004683	calcium/calmodulin-dependent protein kinase activity	5/3668	27/18639	0.185185185185185	0.941021446746638	0.636636857490589	0.915122185794415
GO:0017022	myosin binding	14/3668	76/18639	0.184210526315789	0.936068702290076	0.654033718339834	0.936578017096906
GO:0016881	acid-amino acid ligase activity	4/3668	22/18639	0.181818181818182	0.923911965896699	0.654399326101774	0.936578017096906
GO:0031683	G-protein beta/gamma-subunit complex binding	4/3668	22/18639	0.181818181818182	0.923911965896699	0.654399326101774	0.936578017096906
GO:0061133	endopeptidase activator activity	4/3668	22/18639	0.181818181818182	0.923911965896699	0.654399326101774	0.936578017096906
GO:0005253	monoatomic anion channel activity	19/3668	103/18639	0.184466019417476	0.937366994526262	0.662427796052079	0.943311414635143
GO:0000099	sulfur amino acid transmembrane transporter activity	2/3668	11/18639	0.181818181818182	0.923911965896699	0.668387194624144	0.943311414635143
GO:0008199	ferric iron binding	2/3668	11/18639	0.181818181818182	0.923911965896699	0.668387194624144	0.943311414635143
GO:0016176	superoxide-generating NADPH oxidase activator activity	2/3668	11/18639	0.181818181818182	0.923911965896699	0.668387194624144	0.943311414635143
GO:0016594	glycine binding	2/3668	11/18639	0.181818181818182	0.923911965896699	0.668387194624144	0.943311414635143
GO:0019215	intermediate filament binding	2/3668	11/18639	0.181818181818182	0.923911965896699	0.668387194624144	0.943311414635143
GO:0034511	U3 snoRNA binding	2/3668	11/18639	0.181818181818182	0.923911965896699	0.668387194624144	0.943311414635143
GO:0034594	phosphatidylinositol trisphosphate phosphatase activity	2/3668	11/18639	0.181818181818182	0.923911965896699	0.668387194624144	0.943311414635143
GO:0034713	type I transforming growth factor beta receptor binding	2/3668	11/18639	0.181818181818182	0.923911965896699	0.668387194624144	0.943311414635143
GO:0043522	leucine zipper domain binding	2/3668	11/18639	0.181818181818182	0.923911965896699	0.668387194624144	0.943311414635143
GO:0050786	RAGE receptor binding	2/3668	11/18639	0.181818181818182	0.923911965896699	0.668387194624144	0.943311414635143
GO:0099528	G protein-coupled neurotransmitter receptor activity	2/3668	11/18639	0.181818181818182	0.923911965896699	0.668387194624144	0.943311414635143
GO:0140031	phosphorylation-dependent protein binding	2/3668	11/18639	0.181818181818182	0.923911965896699	0.668387194624144	0.943311414635143
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	7/3668	39/18639	0.179487179487179	0.912066940692895	0.670069481095283	0.943829276799158
GO:0051393	alpha-actinin binding	5/3668	28/18639	0.178571428571429	0.907413537934258	0.67018308980894	0.943829276799158
GO:0016298	lipase activity	24/3668	130/18639	0.184615384615385	0.938125996141263	0.671207926099598	0.944265889645973
GO:0004029	aldehyde dehydrogenase (NAD+) activity	3/3668	17/18639	0.176470588235294	0.896738084546796	0.678838560219968	0.949942519121375
GO:0008429	phosphatidylethanolamine binding	3/3668	17/18639	0.176470588235294	0.896738084546796	0.678838560219968	0.949942519121375
GO:0016018	cyclosporin A binding	3/3668	17/18639	0.176470588235294	0.896738084546796	0.678838560219968	0.949942519121375
GO:0030169	low-density lipoprotein particle binding	3/3668	17/18639	0.176470588235294	0.896738084546796	0.678838560219968	0.949942519121375
GO:0070402	NADPH binding	3/3668	17/18639	0.176470588235294	0.896738084546796	0.678838560219968	0.949942519121375
GO:0005254	chloride channel activity	15/3668	83/18639	0.180722891566265	0.918346231162381	0.686513287802163	0.959665664747786
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	4/3668	23/18639	0.173913043478261	0.883741880422929	0.690333491506513	0.962967837676984
GO:0099186	structural constituent of postsynapse	4/3668	23/18639	0.173913043478261	0.883741880422929	0.690333491506513	0.962967837676984
GO:0015108	chloride transmembrane transporter activity	22/3668	121/18639	0.181818181818182	0.923911965896699	0.696156400533131	0.970066039139521
GO:0009055	electron transfer activity	21/3668	116/18639	0.181034482758621	0.919929586733351	0.701379680168794	0.976314602215992
GO:0005343	organic acid:sodium symporter activity	6/3668	35/18639	0.171428571428571	0.871116996416887	0.712385029334622	0.980268528050171
GO:0043015	gamma-tubulin binding	6/3668	35/18639	0.171428571428571	0.871116996416887	0.712385029334622	0.980268528050171
GO:0015166	polyol transmembrane transporter activity	2/3668	12/18639	0.166666666666667	0.846919302071974	0.716008596845411	0.980268528050171
GO:0016801	hydrolase activity, acting on ether bonds	2/3668	12/18639	0.166666666666667	0.846919302071974	0.716008596845411	0.980268528050171
GO:0016803	ether hydrolase activity	2/3668	12/18639	0.166666666666667	0.846919302071974	0.716008596845411	0.980268528050171
GO:0036009	protein-glutamine N-methyltransferase activity	2/3668	12/18639	0.166666666666667	0.846919302071974	0.716008596845411	0.980268528050171
GO:0097677	STAT family protein binding	2/3668	12/18639	0.166666666666667	0.846919302071974	0.716008596845411	0.980268528050171
GO:0106019	phosphatidylinositol-4,5-bisphosphate phosphatase activity	2/3668	12/18639	0.166666666666667	0.846919302071974	0.716008596845411	0.980268528050171
GO:0140829	bicarbonate:monoatomic anion antiporter activity	2/3668	12/18639	0.166666666666667	0.846919302071974	0.716008596845411	0.980268528050171
GO:0140900	chloride:bicarbonate antiporter activity	2/3668	12/18639	0.166666666666667	0.846919302071974	0.716008596845411	0.980268528050171
GO:1990459	transferrin receptor binding	2/3668	12/18639	0.166666666666667	0.846919302071974	0.716008596845411	0.980268528050171
GO:0003746	translation elongation factor activity	3/3668	18/18639	0.166666666666667	0.846919302071974	0.717577340366779	0.980268528050171
GO:0008525	phosphatidylcholine transporter activity	3/3668	18/18639	0.166666666666667	0.846919302071974	0.717577340366779	0.980268528050171
GO:0015172	acidic amino acid transmembrane transporter activity	3/3668	18/18639	0.166666666666667	0.846919302071974	0.717577340366779	0.980268528050171
GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	3/3668	18/18639	0.166666666666667	0.846919302071974	0.717577340366779	0.980268528050171
GO:0031690	adrenergic receptor binding	3/3668	18/18639	0.166666666666667	0.846919302071974	0.717577340366779	0.980268528050171
GO:0050811	GABA receptor binding	3/3668	18/18639	0.166666666666667	0.846919302071974	0.717577340366779	0.980268528050171
GO:0070628	proteasome binding	3/3668	18/18639	0.166666666666667	0.846919302071974	0.717577340366779	0.980268528050171
GO:0004812	aminoacyl-tRNA ligase activity	7/3668	41/18639	0.170731707317073	0.867575870415193	0.722575884247654	0.983308281600741
GO:0016875	ligase activity, forming carbon-oxygen bonds	7/3668	41/18639	0.170731707317073	0.867575870415193	0.722575884247654	0.983308281600741
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	4/3668	24/18639	0.166666666666667	0.846919302071974	0.723524337407964	0.983308281600741
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	4/3668	24/18639	0.166666666666667	0.846919302071974	0.723524337407964	0.983308281600741
GO:0140612	DNA damage sensor activity	4/3668	24/18639	0.166666666666667	0.846919302071974	0.723524337407964	0.983308281600741
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	10/3668	58/18639	0.172413793103448	0.876123415936525	0.729766302877911	0.989266636680397
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	5/3668	30/18639	0.166666666666667	0.846919302071974	0.730904040423973	0.989266636680397
GO:0022839	monoatomic ion-gated channel activity	5/3668	30/18639	0.166666666666667	0.846919302071974	0.730904040423973	0.989266636680397
GO:0031210	phosphatidylcholine binding	5/3668	30/18639	0.166666666666667	0.846919302071974	0.730904040423973	0.989266636680397
GO:0045505	dynein intermediate chain binding	6/3668	36/18639	0.166666666666667	0.846919302071974	0.738721773737574	0.994751746286785
GO:0055106	ubiquitin-protein transferase regulator activity	6/3668	36/18639	0.166666666666667	0.846919302071974	0.738721773737574	0.994751746286785
GO:0140838	RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity	6/3668	36/18639	0.166666666666667	0.846919302071974	0.738721773737574	0.994751746286785
GO:0140839	RNA polymerase II CTD heptapeptide repeat P3 isomerase activity	6/3668	36/18639	0.166666666666667	0.846919302071974	0.738721773737574	0.994751746286785
GO:0140840	RNA polymerase II CTD heptapeptide repeat P6 isomerase activity	6/3668	36/18639	0.166666666666667	0.846919302071974	0.738721773737574	0.994751746286785
GO:0004864	protein phosphatase inhibitor activity	9/3668	53/18639	0.169811320754717	0.86289891154503	0.741304946078083	0.996199220517953
GO:0008146	sulfotransferase activity	9/3668	53/18639	0.169811320754717	0.86289891154503	0.741304946078083	0.996199220517953
GO:0008307	structural constituent of muscle	7/3668	42/18639	0.166666666666667	0.846919302071974	0.746575970768078	0.997644911868006
GO:0008028	monocarboxylic acid transmembrane transporter activity	12/3668	70/18639	0.171428571428571	0.871116996416887	0.748129329458459	0.997644911868006
GO:0016782	transferase activity, transferring sulphur-containing groups	12/3668	70/18639	0.171428571428571	0.871116996416887	0.748129329458459	0.997644911868006
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	10/3668	59/18639	0.169491525423729	0.861273866513872	0.749921042401123	0.997644911868006
GO:0005229	intracellularly calcium-gated chloride channel activity	3/3668	19/18639	0.157894736842105	0.802344601962923	0.752580795893344	0.997644911868006
GO:0008301	DNA binding, bending	3/3668	19/18639	0.157894736842105	0.802344601962923	0.752580795893344	0.997644911868006
GO:0008574	plus-end-directed microtubule motor activity	3/3668	19/18639	0.157894736842105	0.802344601962923	0.752580795893344	0.997644911868006
GO:0015355	secondary active monocarboxylate transmembrane transporter activity	3/3668	19/18639	0.157894736842105	0.802344601962923	0.752580795893344	0.997644911868006
GO:0022821	solute:potassium antiporter activity	3/3668	19/18639	0.157894736842105	0.802344601962923	0.752580795893344	0.997644911868006
GO:0043395	heparan sulfate proteoglycan binding	3/3668	19/18639	0.157894736842105	0.802344601962923	0.752580795893344	0.997644911868006
GO:0141147	intracellularly calcium-gated channel activity	3/3668	19/18639	0.157894736842105	0.802344601962923	0.752580795893344	0.997644911868006
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	8/3668	48/18639	0.166666666666667	0.846919302071974	0.754289584896539	0.997644911868006
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	2/3668	13/18639	0.153846153846154	0.781771663451053	0.757734759666675	0.997644911868006
GO:0004465	lipoprotein lipase activity	2/3668	13/18639	0.153846153846154	0.781771663451053	0.757734759666675	0.997644911868006
GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	2/3668	13/18639	0.153846153846154	0.781771663451053	0.757734759666675	0.997644911868006
GO:0008253	5'-nucleotidase activity	2/3668	13/18639	0.153846153846154	0.781771663451053	0.757734759666675	0.997644911868006
GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	2/3668	13/18639	0.153846153846154	0.781771663451053	0.757734759666675	0.997644911868006
GO:0045159	myosin II binding	2/3668	13/18639	0.153846153846154	0.781771663451053	0.757734759666675	0.997644911868006
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	2/3668	13/18639	0.153846153846154	0.781771663451053	0.757734759666675	0.997644911868006
GO:0008327	methyl-CpG binding	5/3668	31/18639	0.161290322580645	0.819599324585781	0.758044638858199	0.997644911868006
GO:0004620	phospholipase activity	19/3668	109/18639	0.174311926605505	0.88576881134133	0.758240341798242	0.997644911868006
GO:0005262	calcium channel activity	23/3668	131/18639	0.175572519083969	0.892174531953682	0.761941998830668	1
GO:0023023	MHC protein complex binding	6/3668	37/18639	0.162162162162162	0.824029591205164	0.763285801274726	1
GO:0030551	cyclic nucleotide binding	6/3668	37/18639	0.162162162162162	0.824029591205164	0.763285801274726	1
GO:0042805	actinin binding	6/3668	37/18639	0.162162162162162	0.824029591205164	0.763285801274726	1
GO:0016763	pentosyltransferase activity	8/3668	49/18639	0.163265306122449	0.82963523468275	0.775055828047246	1
GO:0004112	cyclic-nucleotide phosphodiesterase activity	4/3668	26/18639	0.153846153846154	0.781771663451053	0.781796336565376	1
GO:0051139	metal cation:proton antiporter activity	4/3668	26/18639	0.153846153846154	0.781771663451053	0.781796336565376	1
GO:0097602	cullin family protein binding	4/3668	26/18639	0.153846153846154	0.781771663451053	0.781796336565376	1
GO:0030515	snoRNA binding	5/3668	32/18639	0.15625	0.793986845692475	0.783071914167076	1
GO:0001972	retinoic acid binding	3/3668	20/18639	0.15	0.762227371864776	0.784001965004976	1
GO:0004745	all-trans-retinol dehydrogenase (NAD+) activity	3/3668	20/18639	0.15	0.762227371864776	0.784001965004976	1
GO:0140664	ATP-dependent DNA damage sensor activity	3/3668	20/18639	0.15	0.762227371864776	0.784001965004976	1
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	21/3668	122/18639	0.172131147540984	0.874687148041547	0.786221138827628	1
GO:0016836	hydro-lyase activity	10/3668	61/18639	0.163934426229508	0.833035379087187	0.787068031935416	1
GO:0004705	JUN kinase activity	2/3668	14/18639	0.142857142857143	0.725930830347406	0.794041106285557	1
GO:0005347	ATP transmembrane transporter activity	2/3668	14/18639	0.142857142857143	0.725930830347406	0.794041106285557	1
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	2/3668	14/18639	0.142857142857143	0.725930830347406	0.794041106285557	1
GO:0043176	amine binding	2/3668	14/18639	0.142857142857143	0.725930830347406	0.794041106285557	1
GO:0004860	protein kinase inhibitor activity	14/3668	84/18639	0.166666666666667	0.846919302071974	0.795350973215946	1
GO:0008201	heparin binding	30/3668	172/18639	0.174418604651163	0.886310897517182	0.797333165886888	1
GO:0019212	phosphatase inhibitor activity	9/3668	56/18639	0.160714285714286	0.816672184140832	0.799233339257412	1
GO:0019210	kinase inhibitor activity	15/3668	90/18639	0.166666666666667	0.846919302071974	0.801312724638279	1
GO:0016835	carbon-oxygen lyase activity	13/3668	79/18639	0.164556962025316	0.836198804577392	0.804247521779511	1
GO:0033293	monocarboxylic acid binding	13/3668	79/18639	0.164556962025316	0.836198804577392	0.804247521779511	1
GO:0030296	protein tyrosine kinase activator activity	5/3668	33/18639	0.151515151515152	0.769926638247249	0.806043766678243	1
GO:0004364	glutathione transferase activity	4/3668	27/18639	0.148148148148148	0.75281715739731	0.807041463360991	1
GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors	4/3668	27/18639	0.148148148148148	0.75281715739731	0.807041463360991	1
GO:0023026	MHC class II protein complex binding	4/3668	27/18639	0.148148148148148	0.75281715739731	0.807041463360991	1
GO:0035255	ionotropic glutamate receptor binding	4/3668	27/18639	0.148148148148148	0.75281715739731	0.807041463360991	1
GO:0042605	peptide antigen binding	7/3668	45/18639	0.155555555555556	0.790458015267176	0.809572316013258	1
GO:0008373	sialyltransferase activity	3/3668	21/18639	0.142857142857143	0.725930830347406	0.81204214874174	1
GO:0009975	cyclase activity	3/3668	21/18639	0.142857142857143	0.725930830347406	0.81204214874174	1
GO:0036122	BMP binding	3/3668	21/18639	0.142857142857143	0.725930830347406	0.81204214874174	1
GO:0061891	calcium ion sensor activity	3/3668	21/18639	0.142857142857143	0.725930830347406	0.81204214874174	1
GO:1904047	S-adenosyl-L-methionine binding	3/3668	21/18639	0.142857142857143	0.725930830347406	0.81204214874174	1
GO:0004601	peroxidase activity	9/3668	57/18639	0.157894736842105	0.802344601962923	0.816233613236681	1
GO:0016209	antioxidant activity	14/3668	86/18639	0.162790697674419	0.82722350434937	0.823228749945883	1
GO:0005523	tropomyosin binding	2/3668	15/18639	0.133333333333333	0.677535441657579	0.825444277982019	1
GO:0008020	G protein-coupled photoreceptor activity	2/3668	15/18639	0.133333333333333	0.677535441657579	0.825444277982019	1
GO:0008252	nucleotidase activity	2/3668	15/18639	0.133333333333333	0.677535441657579	0.825444277982019	1
GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	2/3668	15/18639	0.133333333333333	0.677535441657579	0.825444277982019	1
GO:0016846	carbon-sulfur lyase activity	2/3668	15/18639	0.133333333333333	0.677535441657579	0.825444277982019	1
GO:0031386	protein tag activity	2/3668	15/18639	0.133333333333333	0.677535441657579	0.825444277982019	1
GO:0045504	dynein heavy chain binding	2/3668	15/18639	0.133333333333333	0.677535441657579	0.825444277982019	1
GO:0140161	monocarboxylate:sodium symporter activity	2/3668	15/18639	0.133333333333333	0.677535441657579	0.825444277982019	1
GO:0141047	molecular tag activity	2/3668	15/18639	0.133333333333333	0.677535441657579	0.825444277982019	1
GO:0018455	alcohol dehydrogenase [NAD(P)+] activity	8/3668	52/18639	0.153846153846154	0.781771663451053	0.829597572225294	1
GO:0016866	intramolecular transferase activity	4/3668	28/18639	0.142857142857143	0.725930830347406	0.829851192286333	1
GO:0046625	sphingolipid binding	4/3668	28/18639	0.142857142857143	0.725930830347406	0.829851192286333	1
GO:0051959	dynein light intermediate chain binding	4/3668	28/18639	0.142857142857143	0.725930830347406	0.829851192286333	1
GO:0008649	rRNA methyltransferase activity	3/3668	22/18639	0.136363636363636	0.692933974422524	0.836933120737524	1
GO:0030021	extracellular matrix structural constituent conferring compression resistance	3/3668	22/18639	0.136363636363636	0.692933974422524	0.836933120737524	1
GO:0140784	metal ion sensor activity	3/3668	22/18639	0.136363636363636	0.692933974422524	0.836933120737524	1
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	22/3668	132/18639	0.166666666666667	0.846919302071974	0.837291251721893	1
GO:0042287	MHC protein binding	6/3668	41/18639	0.146341463414634	0.743636460355879	0.844463816827348	1
GO:0016251	RNA polymerase II general transcription initiation factor activity	8/3668	53/18639	0.150943396226415	0.767021254706693	0.845294039095909	1
GO:0004629	phospholipase C activity	4/3668	29/18639	0.137931034482759	0.70089873274922	0.850368599219692	1
GO:0004198	calcium-dependent cysteine-type endopeptidase activity	2/3668	16/18639	0.125	0.63518947655398	0.852467510805776	1
GO:0015378	sodium:chloride symporter activity	2/3668	16/18639	0.125	0.63518947655398	0.852467510805776	1
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	2/3668	16/18639	0.125	0.63518947655398	0.852467510805776	1
GO:0022841	potassium ion leak channel activity	2/3668	16/18639	0.125	0.63518947655398	0.852467510805776	1
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	3/3668	23/18639	0.130434782608696	0.662806410317197	0.858923065122176	1
GO:0004022	alcohol dehydrogenase (NAD+) activity	3/3668	23/18639	0.130434782608696	0.662806410317197	0.858923065122176	1
GO:0005283	amino acid:sodium symporter activity	3/3668	23/18639	0.130434782608696	0.662806410317197	0.858923065122176	1
GO:0031681	G-protein beta-subunit binding	3/3668	23/18639	0.130434782608696	0.662806410317197	0.858923065122176	1
GO:0140102	catalytic activity, acting on a rRNA	3/3668	23/18639	0.130434782608696	0.662806410317197	0.858923065122176	1
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	3/3668	23/18639	0.130434782608696	0.662806410317197	0.858923065122176	1
GO:0031492	nucleosomal DNA binding	6/3668	42/18639	0.142857142857143	0.725930830347406	0.860778457837226	1
GO:0004867	serine-type endopeptidase inhibitor activity	15/3668	95/18639	0.157894736842105	0.802344601962923	0.862495084999171	1
GO:0005484	SNAP receptor activity	5/3668	36/18639	0.138888888888889	0.705766085059978	0.863473235455737	1
GO:0033612	receptor serine/threonine kinase binding	4/3668	30/18639	0.133333333333333	0.677535441657579	0.868747762111341	1
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	9/3668	61/18639	0.147540983606557	0.749731841178469	0.873391742122855	1
GO:0035254	glutamate receptor binding	7/3668	49/18639	0.142857142857143	0.725930830347406	0.873857615886652	1
GO:0015081	sodium ion transmembrane transporter activity	27/3668	164/18639	0.164634146341463	0.836591017900364	0.874118842007405	1
GO:0015171	amino acid transmembrane transporter activity	16/3668	102/18639	0.156862745098039	0.797100519597152	0.87524509991642	1
GO:0009881	photoreceptor activity	2/3668	17/18639	0.117647058823529	0.597825389697864	0.87561803755055	1
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	2/3668	17/18639	0.117647058823529	0.597825389697864	0.87561803755055	1
GO:0031489	myosin V binding	2/3668	17/18639	0.117647058823529	0.597825389697864	0.87561803755055	1
GO:0036041	long-chain fatty acid binding	2/3668	17/18639	0.117647058823529	0.597825389697864	0.87561803755055	1
GO:0045125	bioactive lipid receptor activity	2/3668	17/18639	0.117647058823529	0.597825389697864	0.87561803755055	1
GO:0070492	oligosaccharide binding	2/3668	17/18639	0.117647058823529	0.597825389697864	0.87561803755055	1
GO:0001091	RNA polymerase II general transcription initiation factor binding	3/3668	24/18639	0.125	0.63518947655398	0.878265740509921	1
GO:0004806	triacylglycerol lipase activity	3/3668	24/18639	0.125	0.63518947655398	0.878265740509921	1
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	3/3668	24/18639	0.125	0.63518947655398	0.878265740509921	1
GO:0047499	calcium-independent phospholipase A2 activity	4/3668	31/18639	0.129032258064516	0.655679459668625	0.88514822481551	1
GO:0003680	minor groove of adenine-thymine-rich DNA binding	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0004862	cAMP-dependent protein kinase inhibitor activity	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0004935	adrenergic receptor activity	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0005031	tumor necrosis factor receptor activity	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0005528	FK506 binding	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0008140	cAMP response element binding protein binding	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0008519	ammonium channel activity	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0015187	glycine transmembrane transporter activity	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0016868	intramolecular phosphotransferase activity	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0016889	DNA endonuclease activity, producing 3'-phosphomonoesters	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0019531	oxalate transmembrane transporter activity	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0030957	Tat protein binding	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0031996	thioesterase binding	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0032052	bile acid binding	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0032395	MHC class II receptor activity	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0036435	K48-linked polyubiquitin modification-dependent protein binding	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0042166	acetylcholine binding	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0043208	glycosphingolipid binding	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0047429	nucleoside triphosphate diphosphatase activity	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0050308	sugar-phosphatase activity	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0051378	serotonin binding	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0070739	protein-glutamic acid ligase activity	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0070740	tubulin-glutamic acid ligase activity	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0141109	transporter activator activity	1/3668	10/18639	0.1	0.508151581243184	0.888307238399775	1
GO:0016248	channel inhibitor activity	6/3668	44/18639	0.136363636363636	0.692933974422524	0.889166475524027	1
GO:0030020	extracellular matrix structural constituent conferring tensile strength	6/3668	44/18639	0.136363636363636	0.692933974422524	0.889166475524027	1
GO:0015280	ligand-gated sodium channel activity	2/3668	18/18639	0.111111111111111	0.564612868047982	0.895373124698522	1
GO:0015373	monoatomic anion:sodium symporter activity	2/3668	18/18639	0.111111111111111	0.564612868047982	0.895373124698522	1
GO:0032393	MHC class I receptor activity	2/3668	18/18639	0.111111111111111	0.564612868047982	0.895373124698522	1
GO:0047498	calcium-dependent phospholipase A2 activity	4/3668	32/18639	0.125	0.63518947655398	0.899730554908143	1
GO:0141110	transporter inhibitor activity	6/3668	45/18639	0.133333333333333	0.677535441657579	0.901411730833376	1
GO:0046873	metal ion transmembrane transporter activity	78/3668	450/18639	0.173333333333333	0.880796074154853	0.909337160777959	1
GO:0008198	ferrous iron binding	3/3668	26/18639	0.115384615384615	0.58632874758829	0.910005762226164	1
GO:0030247	polysaccharide binding	3/3668	26/18639	0.115384615384615	0.58632874758829	0.910005762226164	1
GO:0120014	phospholipid transfer activity	3/3668	26/18639	0.115384615384615	0.58632874758829	0.910005762226164	1
GO:0003953	NAD+ nucleosidase activity	1/3668	11/18639	0.0909090909090909	0.461955982948349	0.910299242777339	1
GO:0005536	D-glucose binding	1/3668	11/18639	0.0909090909090909	0.461955982948349	0.910299242777339	1
GO:0008503	benzodiazepine receptor activity	1/3668	11/18639	0.0909090909090909	0.461955982948349	0.910299242777339	1
GO:0010854	adenylate cyclase regulator activity	1/3668	11/18639	0.0909090909090909	0.461955982948349	0.910299242777339	1
GO:0015217	ADP transmembrane transporter activity	1/3668	11/18639	0.0909090909090909	0.461955982948349	0.910299242777339	1
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	1/3668	11/18639	0.0909090909090909	0.461955982948349	0.910299242777339	1
GO:0016725	oxidoreductase activity, acting on CH or CH2 groups	1/3668	11/18639	0.0909090909090909	0.461955982948349	0.910299242777339	1
GO:0019203	carbohydrate phosphatase activity	1/3668	11/18639	0.0909090909090909	0.461955982948349	0.910299242777339	1
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	2/3668	19/18639	0.105263157894737	0.534896401308615	0.912172222205013	1
GO:0022840	leak channel activity	2/3668	19/18639	0.105263157894737	0.534896401308615	0.912172222205013	1
GO:0022842	narrow pore channel activity	2/3668	19/18639	0.105263157894737	0.534896401308615	0.912172222205013	1
GO:0019956	chemokine binding	4/3668	33/18639	0.121212121212121	0.615941310597799	0.912652870526061	1
GO:0061134	peptidase regulator activity	37/3668	226/18639	0.163716814159292	0.831929579911408	0.912708745293158	1
GO:0008135	translation factor activity, RNA binding	12/3668	83/18639	0.144578313253012	0.734676984929905	0.913821966538861	1
GO:0004252	serine-type endopeptidase activity	28/3668	176/18639	0.159090909090909	0.808422970159611	0.915867733652307	1
GO:0005544	calcium-dependent phospholipid binding	7/3668	53/18639	0.132075471698113	0.671143597868357	0.919027336122574	1
GO:0180051	translation factor activity	12/3668	84/18639	0.142857142857143	0.725930830347406	0.921458963383484	1
GO:0004896	cytokine receptor activity	14/3668	96/18639	0.145833333333333	0.741054389312977	0.921749094590996	1
GO:0015252	proton channel activity	3/3668	27/18639	0.111111111111111	0.564612868047982	0.92287629958431	1
GO:0001614	purinergic nucleotide receptor activity	2/3668	20/18639	0.1	0.508151581243184	0.926413361893906	1
GO:0016502	nucleotide receptor activity	2/3668	20/18639	0.1	0.508151581243184	0.926413361893906	1
GO:0140828	metal cation:monoatomic cation antiporter activity	5/3668	41/18639	0.121951219512195	0.619697050296566	0.927297475986975	1
GO:0003720	telomerase activity	1/3668	12/18639	0.0833333333333333	0.423459651035987	0.92796202877115	1
GO:0004000	adenosine deaminase activity	1/3668	12/18639	0.0833333333333333	0.423459651035987	0.92796202877115	1
GO:0005527	macrolide binding	1/3668	12/18639	0.0833333333333333	0.423459651035987	0.92796202877115	1
GO:0008179	adenylate cyclase binding	1/3668	12/18639	0.0833333333333333	0.423459651035987	0.92796202877115	1
GO:0008603	cAMP-dependent protein kinase regulator activity	1/3668	12/18639	0.0833333333333333	0.423459651035987	0.92796202877115	1
GO:0015132	prostaglandin transmembrane transporter activity	1/3668	12/18639	0.0833333333333333	0.423459651035987	0.92796202877115	1
GO:0015269	calcium-activated potassium channel activity	1/3668	12/18639	0.0833333333333333	0.423459651035987	0.92796202877115	1
GO:0016840	carbon-nitrogen lyase activity	1/3668	12/18639	0.0833333333333333	0.423459651035987	0.92796202877115	1
GO:0070679	inositol 1,4,5 trisphosphate binding	1/3668	12/18639	0.0833333333333333	0.423459651035987	0.92796202877115	1
GO:0070851	growth factor receptor binding	21/3668	139/18639	0.151079136690647	0.767711022022077	0.932782588621337	1
GO:0005201	extracellular matrix structural constituent	26/3668	168/18639	0.154761904761905	0.78642506620969	0.933234884113662	1
GO:0004623	phospholipase A2 activity	4/3668	35/18639	0.114285714285714	0.580744664277925	0.934122603104533	1
GO:0048306	calcium-dependent protein binding	11/3668	80/18639	0.1375	0.698708424209379	0.935690174754884	1
GO:0001846	opsonin binding	2/3668	21/18639	0.0952380952380952	0.483953886898271	0.938452436962555	1
GO:0005248	voltage-gated sodium channel activity	2/3668	21/18639	0.0952380952380952	0.483953886898271	0.938452436962555	1
GO:0070182	DNA polymerase binding	2/3668	21/18639	0.0952380952380952	0.483953886898271	0.938452436962555	1
GO:0003964	RNA-directed DNA polymerase activity	1/3668	13/18639	0.0769230769230769	0.390885831725526	0.942147634529857	1
GO:0005035	death receptor activity	1/3668	13/18639	0.0769230769230769	0.390885831725526	0.942147634529857	1
GO:0015651	quaternary ammonium group transmembrane transporter activity	1/3668	13/18639	0.0769230769230769	0.390885831725526	0.942147634529857	1
GO:0030955	potassium ion binding	1/3668	13/18639	0.0769230769230769	0.390885831725526	0.942147634529857	1
GO:0035325	Toll-like receptor binding	1/3668	13/18639	0.0769230769230769	0.390885831725526	0.942147634529857	1
GO:0039706	co-receptor binding	1/3668	13/18639	0.0769230769230769	0.390885831725526	0.942147634529857	1
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/3668	13/18639	0.0769230769230769	0.390885831725526	0.942147634529857	1
GO:0071714	icosanoid transmembrane transporter activity	1/3668	13/18639	0.0769230769230769	0.390885831725526	0.942147634529857	1
GO:0071837	HMG box domain binding	1/3668	13/18639	0.0769230769230769	0.390885831725526	0.942147634529857	1
GO:0089720	caspase binding	1/3668	13/18639	0.0769230769230769	0.390885831725526	0.942147634529857	1
GO:1901338	catecholamine binding	1/3668	13/18639	0.0769230769230769	0.390885831725526	0.942147634529857	1
GO:0004869	cysteine-type endopeptidase inhibitor activity	4/3668	36/18639	0.111111111111111	0.564612868047982	0.942953774060632	1
GO:0004181	metallocarboxypeptidase activity	3/3668	29/18639	0.103448275862069	0.525674049561915	0.943693625526265	1
GO:0005416	amino acid:monoatomic cation symporter activity	3/3668	29/18639	0.103448275862069	0.525674049561915	0.943693625526265	1
GO:0008200	ion channel inhibitor activity	5/3668	43/18639	0.116279069767442	0.590873931678121	0.944264882050077	1
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	19/3668	130/18639	0.146153846153846	0.7426830802785	0.94591401402203	1
GO:0005243	gap junction channel activity	2/3668	22/18639	0.0909090909090909	0.461955982948349	0.948604368585058	1
GO:0070566	adenylyltransferase activity	3/3668	30/18639	0.1	0.508151581243184	0.952020943683478	1
GO:0003743	translation initiation factor activity	6/3668	51/18639	0.117647058823529	0.597825389697864	0.953014122461908	1
GO:0005539	glycosaminoglycan binding	38/3668	242/18639	0.15702479338843	0.797923970547149	0.953414937906624	1
GO:0005313	L-glutamate transmembrane transporter activity	1/3668	14/18639	0.0714285714285714	0.362965415173703	0.953540444394803	1
GO:0008191	metalloendopeptidase inhibitor activity	1/3668	14/18639	0.0714285714285714	0.362965415173703	0.953540444394803	1
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/3668	14/18639	0.0714285714285714	0.362965415173703	0.953540444394803	1
GO:1990825	sequence-specific mRNA binding	1/3668	14/18639	0.0714285714285714	0.362965415173703	0.953540444394803	1
GO:0043274	phospholipase binding	2/3668	23/18639	0.0869565217391304	0.441870940211465	0.957145445105333	1
GO:0005501	retinoid binding	4/3668	38/18639	0.105263157894737	0.534896401308615	0.957451135029921	1
GO:0019840	isoprenoid binding	4/3668	38/18639	0.105263157894737	0.534896401308615	0.957451135029921	1
GO:0019843	rRNA binding	8/3668	65/18639	0.123076923076923	0.625417330760842	0.957739224244091	1
GO:0005164	tumor necrosis factor receptor binding	3/3668	31/18639	0.0967741935483871	0.491759594751469	0.959185877847904	1
GO:0004089	carbonate dehydratase activity	1/3668	15/18639	0.0666666666666667	0.33876772082879	0.962690170567144	1
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/3668	15/18639	0.0666666666666667	0.33876772082879	0.962690170567144	1
GO:0017081	chloride channel regulator activity	1/3668	15/18639	0.0666666666666667	0.33876772082879	0.962690170567144	1
GO:0030553	cGMP binding	1/3668	15/18639	0.0666666666666667	0.33876772082879	0.962690170567144	1
GO:0031005	filamin binding	1/3668	15/18639	0.0666666666666667	0.33876772082879	0.962690170567144	1
GO:0050700	CARD domain binding	1/3668	15/18639	0.0666666666666667	0.33876772082879	0.962690170567144	1
GO:0030291	protein serine/threonine kinase inhibitor activity	5/3668	46/18639	0.108695652173913	0.552338675264331	0.963067663819182	1
GO:0005246	calcium channel regulator activity	6/3668	53/18639	0.113207547169811	0.57526594103002	0.963784219390994	1
GO:0005540	hyaluronic acid binding	2/3668	24/18639	0.0833333333333333	0.423459651035987	0.96431632734128	1
GO:0019957	C-C chemokine binding	2/3668	24/18639	0.0833333333333333	0.423459651035987	0.96431632734128	1
GO:0031369	translation initiation factor binding	3/3668	32/18639	0.09375	0.476392107415485	0.965336428496844	1
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	3/3668	32/18639	0.09375	0.476392107415485	0.965336428496844	1
GO:0099095	ligand-gated monoatomic anion channel activity	5/3668	47/18639	0.106382978723404	0.540586788556579	0.967904067306567	1
GO:0061791	GTPase motor activity	4/3668	40/18639	0.1	0.508151581243184	0.968473343343358	1
GO:1990606	membrane scission GTPase motor activity	4/3668	40/18639	0.1	0.508151581243184	0.968473343343358	1
GO:0005149	interleukin-1 receptor binding	1/3668	16/18639	0.0625	0.31759473827699	0.970038347884569	1
GO:0022848	acetylcholine-gated monoatomic cation-selective channel activity	1/3668	16/18639	0.0625	0.31759473827699	0.970038347884569	1
GO:0055102	lipase inhibitor activity	1/3668	16/18639	0.0625	0.31759473827699	0.970038347884569	1
GO:0061809	NAD+ nucleosidase activity, cyclic ADP-ribose generating	1/3668	16/18639	0.0625	0.31759473827699	0.970038347884569	1
GO:0001848	complement binding	2/3668	25/18639	0.08	0.406521264994547	0.970325367374642	1
GO:0015271	outward rectifier potassium channel activity	2/3668	25/18639	0.08	0.406521264994547	0.970325367374642	1
GO:0003777	microtubule motor activity	8/3668	68/18639	0.117647058823529	0.597825389697864	0.970487656686952	1
GO:0019003	GDP binding	9/3668	75/18639	0.12	0.609781897491821	0.971944584017282	1
GO:0004550	nucleoside diphosphate kinase activity	1/3668	17/18639	0.0588235294117647	0.298912694848932	0.975939617280445	1
GO:0008569	minus-end-directed microtubule motor activity	1/3668	17/18639	0.0588235294117647	0.298912694848932	0.975939617280445	1
GO:0015347	sodium-independent organic anion transmembrane transporter activity	1/3668	17/18639	0.0588235294117647	0.298912694848932	0.975939617280445	1
GO:0030548	acetylcholine receptor regulator activity	1/3668	17/18639	0.0588235294117647	0.298912694848932	0.975939617280445	1
GO:0045236	CXCR chemokine receptor binding	1/3668	17/18639	0.0588235294117647	0.298912694848932	0.975939617280445	1
GO:0016229	steroid dehydrogenase activity	3/3668	35/18639	0.0857142857142857	0.435558498208444	0.978950735292056	1
GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	1/3668	18/18639	0.0555555555555556	0.282306434023991	0.98067882272644	1
GO:0022851	GABA-gated chloride ion channel activity	1/3668	18/18639	0.0555555555555556	0.282306434023991	0.98067882272644	1
GO:0046933	proton-transporting ATP synthase activity, rotational mechanism	1/3668	18/18639	0.0555555555555556	0.282306434023991	0.98067882272644	1
GO:0099602	neurotransmitter receptor regulator activity	1/3668	18/18639	0.0555555555555556	0.282306434023991	0.98067882272644	1
GO:0003924	GTPase activity	51/3668	331/18639	0.154078549848943	0.78295258741397	0.981734732180452	1
GO:0005272	sodium channel activity	5/3668	51/18639	0.0980392156862745	0.49818782474822	0.98195558241527	1
GO:0005231	excitatory extracellular ligand-gated monoatomic ion channel activity	3/3668	36/18639	0.0833333333333333	0.423459651035987	0.982223186313095	1
GO:0051537	2 iron, 2 sulfur cluster binding	2/3668	28/18639	0.0714285714285714	0.362965415173703	0.983050883784398	1
GO:0015459	potassium channel regulator activity	6/3668	59/18639	0.101694915254237	0.516764319908323	0.983976832856038	1
GO:0070888	E-box binding	6/3668	59/18639	0.101694915254237	0.516764319908323	0.983976832856038	1
GO:0004890	GABA-A receptor activity	1/3668	19/18639	0.0526315789473684	0.267448200654308	0.984484744977631	1
GO:0016918	retinal binding	1/3668	19/18639	0.0526315789473684	0.267448200654308	0.984484744977631	1
GO:0034987	immunoglobulin receptor binding	1/3668	19/18639	0.0526315789473684	0.267448200654308	0.984484744977631	1
GO:0042834	peptidoglycan binding	1/3668	19/18639	0.0526315789473684	0.267448200654308	0.984484744977631	1
GO:0070003	threonine-type peptidase activity	1/3668	19/18639	0.0526315789473684	0.267448200654308	0.984484744977631	1
GO:0022829	wide pore channel activity	3/3668	37/18639	0.0810810810810811	0.412014795602582	0.985005500741637	1
GO:0043325	phosphatidylinositol-3,4-bisphosphate binding	2/3668	29/18639	0.0689655172413793	0.35044936637461	0.985966236247964	1
GO:0141108	transporter regulator activity	23/3668	170/18639	0.135294117647059	0.687499198152543	0.986264805055539	1
GO:0019001	guanyl nucleotide binding	62/3668	400/18639	0.155	0.787634950926936	0.987505555601706	1
GO:0032561	guanyl ribonucleotide binding	62/3668	400/18639	0.155	0.787634950926936	0.987505555601706	1
GO:0010851	cyclase regulator activity	1/3668	20/18639	0.05	0.254075790621592	0.987541133560985	1
GO:0015464	acetylcholine receptor activity	1/3668	20/18639	0.05	0.254075790621592	0.987541133560985	1
GO:0030627	pre-mRNA 5'-splice site binding	1/3668	20/18639	0.05	0.254075790621592	0.987541133560985	1
GO:0003774	cytoskeletal motor activity	20/3668	153/18639	0.130718954248366	0.664250432997627	0.988045726294985	1
GO:0005525	GTP binding	58/3668	378/18639	0.153439153439153	0.779703484447214	0.988182090007765	1
GO:0061135	endopeptidase regulator activity	25/3668	184/18639	0.135869565217391	0.690423344080413	0.988274536626307	1
GO:0099106	ion channel regulator activity	21/3668	160/18639	0.13125	0.666948950381679	0.988904800635004	1
GO:0005506	iron ion binding	20/3668	154/18639	0.12987012987013	0.659937118497642	0.989138120532215	1
GO:0005504	fatty acid binding	4/3668	47/18639	0.0851063829787234	0.432469430845263	0.989443148880708	1
GO:0004866	endopeptidase inhibitor activity	21/3668	161/18639	0.130434782608696	0.662806410317197	0.989907647562814	1
GO:0015125	bile acid transmembrane transporter activity	1/3668	21/18639	0.0476190476190476	0.241976943449135	0.989995568390906	1
GO:0019200	carbohydrate kinase activity	1/3668	21/18639	0.0476190476190476	0.241976943449135	0.989995568390906	1
GO:0051428	peptide hormone receptor binding	1/3668	21/18639	0.0476190476190476	0.241976943449135	0.989995568390906	1
GO:0016247	channel regulator activity	22/3668	168/18639	0.130952380952381	0.665436594485122	0.990627943982077	1
GO:0038187	pattern recognition receptor activity	4/3668	48/18639	0.0833333333333333	0.423459651035987	0.991015356916122	1
GO:0030414	peptidase inhibitor activity	22/3668	169/18639	0.130177514792899	0.661499099843199	0.991472626604635	1
GO:0005200	structural constituent of cytoskeleton	13/3668	112/18639	0.116071428571429	0.589818799657268	0.991881064423825	1
GO:0033691	sialic acid binding	1/3668	22/18639	0.0454545454545455	0.230977991474175	0.99196657790547	1
GO:0001530	lipopolysaccharide binding	3/3668	41/18639	0.0731707317073171	0.37181823017794	0.992495357415834	1
GO:0005212	structural constituent of eye lens	1/3668	23/18639	0.0434782608695652	0.220935470105732	0.993549356669113	1
GO:0016493	C-C chemokine receptor activity	1/3668	23/18639	0.0434782608695652	0.220935470105732	0.993549356669113	1
GO:0016917	GABA receptor activity	1/3668	23/18639	0.0434782608695652	0.220935470105732	0.993549356669113	1
GO:0042056	chemoattractant activity	3/3668	42/18639	0.0714285714285714	0.362965415173703	0.993704119756587	1
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	2/3668	34/18639	0.0588235294117647	0.298912694848932	0.994608613869316	1
GO:0005245	voltage-gated calcium channel activity	3/3668	43/18639	0.0697674418604651	0.354524359006873	0.994723192791793	1
GO:0008083	growth factor activity	20/3668	162/18639	0.123456790123457	0.627347631164425	0.995089288933285	1
GO:0005251	delayed rectifier potassium channel activity	1/3668	25/18639	0.04	0.203260632497274	0.995840982551303	1
GO:0046906	tetrapyrrole binding	18/3668	152/18639	0.118421052631579	0.601758451472192	0.996373443048028	1
GO:0001637	G protein-coupled chemoattractant receptor activity	1/3668	26/18639	0.0384615384615385	0.195442915862763	0.996660541807874	1
GO:0004435	phosphatidylinositol phospholipase C activity	1/3668	26/18639	0.0384615384615385	0.195442915862763	0.996660541807874	1
GO:0004950	chemokine receptor activity	1/3668	26/18639	0.0384615384615385	0.195442915862763	0.996660541807874	1
GO:0004857	enzyme inhibitor activity	61/3668	416/18639	0.146634615384615	0.745126116726785	0.997016562582751	1
GO:0005104	fibroblast growth factor receptor binding	1/3668	27/18639	0.037037037037037	0.188204289349328	0.99731863736736	1
GO:0071855	neuropeptide receptor binding	2/3668	40/18639	0.05	0.254075790621592	0.998328404124012	1
GO:0048019	receptor antagonist activity	1/3668	30/18639	0.0333333333333333	0.169383860414395	0.998612094764353	1
GO:0020037	heme binding	15/3668	142/18639	0.105633802816901	0.536779839341392	0.998852465289325	1
GO:0140375	immune receptor activity	17/3668	156/18639	0.108974358974359	0.553754928277829	0.998906004860697	1
GO:0099094	ligand-gated monoatomic cation channel activity	14/3668	136/18639	0.102941176470588	0.523097215985631	0.998972247741755	1
GO:0046982	protein heterodimerization activity	50/3668	369/18639	0.13550135501355	0.688552278107296	0.999276741568904	1
GO:0019239	deaminase activity	1/3668	33/18639	0.0303030303030303	0.15398532764945	0.999281689005747	1
GO:0042923	neuropeptide binding	1/3668	33/18639	0.0303030303030303	0.15398532764945	0.999281689005747	1
GO:0015079	potassium ion transmembrane transporter activity	17/3668	160/18639	0.10625	0.539911055070883	0.999319492059651	1
GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	1/3668	34/18639	0.0294117647058824	0.149456347424466	0.999423297343214	1
GO:0051427	hormone receptor binding	1/3668	34/18639	0.0294117647058824	0.149456347424466	0.999423297343214	1
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	3/3668	56/18639	0.0535714285714286	0.272224061380277	0.999505173030037	1
GO:0003730	mRNA 3'-UTR binding	32/3668	262/18639	0.122137404580153	0.620643152663431	0.999532432801964	1
GO:0008188	neuropeptide receptor activity	2/3668	48/18639	0.0416666666666667	0.211729825517993	0.999659260271682	1
GO:0030280	structural constituent of skin epidermis	1/3668	37/18639	0.027027027027027	0.137338265200861	0.99970157453877	1
GO:0001664	G protein-coupled receptor binding	36/3668	297/18639	0.121212121212121	0.615941310597799	0.999816984376771	1
GO:0022824	transmitter-gated monoatomic ion channel activity	3/3668	63/18639	0.0476190476190476	0.241976943449135	0.999867481305985	1
GO:0022835	transmitter-gated channel activity	3/3668	63/18639	0.0476190476190476	0.241976943449135	0.999867481305985	1
GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	2/3668	53/18639	0.0377358490566038	0.191755313676673	0.999875523124076	1
GO:0008227	G protein-coupled amine receptor activity	1/3668	41/18639	0.024390243902439	0.123939410059313	0.999876044017751	1
GO:0005230	extracellular ligand-gated monoatomic ion channel activity	4/3668	73/18639	0.0547945205479452	0.278439222599005	0.999879523842435	1
GO:0030547	signaling receptor inhibitor activity	1/3668	44/18639	0.0227272727272727	0.115488995737087	0.999935874469447	1
GO:0022834	ligand-gated channel activity	18/3668	188/18639	0.0957446808510638	0.486528109700921	0.99995074009051	1
GO:0098960	postsynaptic neurotransmitter receptor activity	3/3668	69/18639	0.0434782608695652	0.220935470105732	0.999957930281985	1
GO:0005267	potassium channel activity	9/3668	124/18639	0.0725806451612903	0.368819696063602	0.999970600074326	1
GO:0005126	cytokine receptor binding	30/3668	275/18639	0.109090909090909	0.554347179538019	0.999970742741043	1
GO:0005261	monoatomic cation channel activity	40/3668	341/18639	0.117302052785924	0.596072236062386	0.99997114633469	1
GO:0015276	ligand-gated monoatomic ion channel activity	17/3668	186/18639	0.0913978494623656	0.464439617265276	0.999975159380332	1
GO:0005216	monoatomic ion channel activity	56/3668	448/18639	0.125	0.63518947655398	0.999982223288652	1
GO:0030594	neurotransmitter receptor activity	5/3668	97/18639	0.0515463917525773	0.261933804764528	0.999991559432662	1
GO:0005179	hormone activity	9/3668	132/18639	0.0681818181818182	0.346466987211262	0.999991740964011	1
GO:0022832	voltage-gated channel activity	14/3668	175/18639	0.08	0.406521264994547	0.999994985832477	1
GO:0005244	voltage-gated monoatomic ion channel activity	13/3668	173/18639	0.0751445086705202	0.38184800902667	0.9999978836392	1
GO:0005249	voltage-gated potassium channel activity	4/3668	98/18639	0.0408163265306122	0.207408808670687	0.999998852668845	1
GO:0022836	gated channel activity	32/3668	318/18639	0.10062893081761	0.511347503137796	0.999999065386238	1
GO:0004497	monooxygenase activity	4/3668	106/18639	0.0377358490566038	0.191755313676673	0.999999752710347	1
GO:0003823	antigen binding	11/3668	174/18639	0.0632183908045977	0.321245252510059	0.999999862509378	1
GO:0042379	chemokine receptor binding	1/3668	72/18639	0.0138888888888889	0.0705766085059978	0.999999864169598	1
GO:0022843	voltage-gated monoatomic cation channel activity	7/3668	143/18639	0.048951048951049	0.24874552927988	0.99999993700178	1
GO:0008528	G protein-coupled peptide receptor activity	3/3668	122/18639	0.0245901639344262	0.124955306863078	0.999999998930663	1
GO:0001653	peptide receptor activity	3/3668	128/18639	0.0234375	0.119098026853871	0.999999999687661	1
GO:0003735	structural constituent of ribosome	7/3668	175/18639	0.04	0.203260632497274	0.999999999822625	1
GO:0005125	cytokine activity	10/3668	234/18639	0.0427350427350427	0.21715879540307	0.999999999999204	1
GO:0030371	translation repressor activity	8/3668	329/18639	0.0243161094224924	0.123562694527218	1	1
GO:0045182	translation regulator activity	13/3668	356/18639	0.0365168539325843	0.185560970678691	1	1