ID	Description	GeneRatio	BgRatio	RichFactor	FoldEnrichment	pvalue	p.adjust
GO:0003735	structural constituent of ribosome	35/254	175/18639	0.2	14.6763779527559	7.19564224819631e-31	4.38934177139975e-28
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	11/254	68/18639	0.161764705882353	11.870599814729	1.87292718483659e-09	5.71242791375159e-07
GO:0022853	active monoatomic ion transmembrane transporter activity	13/254	118/18639	0.110169491525424	8.08444548245029	8.03921114391712e-09	1.63463959926315e-06
GO:0008137	NADH dehydrogenase (ubiquinone) activity	8/254	41/18639	0.195121951219512	14.3184175148838	6.90065993667731e-08	1.05235064034329e-05
GO:0003954	NADH dehydrogenase activity	8/254	44/18639	0.181818181818182	13.3421617752326	1.23562047816568e-07	1.50745698336213e-05
GO:0015399	primary active transmembrane transporter activity	13/254	166/18639	0.0783132530120482	5.7467744995731	4.66876947997463e-07	4.70676064444715e-05
GO:0009055	electron transfer activity	11/254	116/18639	0.0948275862068965	6.95862747759978	5.40120073952952e-07	4.70676064444715e-05
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	8/254	58/18639	0.137931034482759	10.1216399674179	1.1336090699182e-06	8.64376915812625e-05
GO:0015078	proton transmembrane transporter activity	13/254	185/18639	0.0702702702702703	5.15656522664397	1.5982648696029e-06	0.000108326841161974
GO:0022804	active transmembrane transporter activity	19/254	457/18639	0.0415754923413567	3.0508881958683	1.75751186702539e-05	0.00107208223888549
GO:0016651	oxidoreductase activity, acting on NAD(P)H	8/254	88/18639	0.0909090909090909	6.67108088761632	2.67441605519586e-05	0.00148308526697225
GO:0005178	integrin binding	9/254	161/18639	0.0559006211180124	4.10209321660879	0.000371726029434503	0.0178579840321852
GO:1990948	ubiquitin ligase inhibitor activity	3/254	11/18639	0.272727272727273	20.013242662849	0.000380579987571161	0.0178579840321852
GO:1901681	sulfur compound binding	12/254	275/18639	0.0436363636363636	3.20211882605583	0.000411219313475053	0.0179174129442702
GO:0005539	glycosaminoglycan binding	11/254	242/18639	0.0454545454545455	3.33554044380816	0.000506957794011745	0.0206162836231443
GO:0008201	heparin binding	9/254	172/18639	0.0523255813953488	3.83975004577916	0.000601087674327762	0.0229164675837459
GO:0001968	fibronectin binding	4/254	30/18639	0.133333333333333	9.78425196850394	0.000698398199298303	0.0247739991950953
GO:0046332	SMAD binding	6/254	79/18639	0.0759493670886076	5.57330808332503	0.000731036041822485	0.0247739991950953
GO:0031386	protein tag activity	3/254	15/18639	0.2	14.6763779527559	0.00100796346168481	0.0292789386489397
GO:0055105	ubiquitin-protein transferase inhibitor activity	3/254	15/18639	0.2	14.6763779527559	0.00100796346168481	0.0292789386489397
GO:0141047	molecular tag activity	3/254	15/18639	0.2	14.6763779527559	0.00100796346168481	0.0292789386489397
GO:0005507	copper ion binding	5/254	63/18639	0.0793650793650794	5.82395950506187	0.00166823843179476	0.0462557019724912
GO:0019843	rRNA binding	5/254	65/18639	0.0769230769230769	5.64476075105996	0.00191775511710165	0.0508622009318263
GO:0098631	cell adhesion mediator activity	5/254	76/18639	0.0657894736842105	4.82775590551181	0.003801559159561	0.0966229619721755
GO:0070412	R-SMAD binding	3/254	26/18639	0.115384615384615	8.46714112658995	0.00515756040173597	0.125844473802358
GO:0051287	NAD binding	4/254	54/18639	0.0740740740740741	5.43569553805774	0.0062467824881864	0.143912681397091
GO:0045499	chemorepellent activity	3/254	28/18639	0.107142857142857	7.86234533183352	0.00636990557003516	0.143912681397091
GO:0005345	purine nucleobase transmembrane transporter activity	2/254	10/18639	0.2	14.6763779527559	0.00774471928014089	0.162906164168481
GO:0016783	sulfurtransferase activity	2/254	10/18639	0.2	14.6763779527559	0.00774471928014089	0.162906164168481
GO:0008271	secondary active sulfate transmembrane transporter activity	2/254	11/18639	0.181818181818182	13.3421617752326	0.00938119467848971	0.17882902355871
GO:0015205	nucleobase transmembrane transporter activity	2/254	11/18639	0.181818181818182	13.3421617752326	0.00938119467848971	0.17882902355871
GO:0097493	structural molecule activity conferring elasticity	2/254	11/18639	0.181818181818182	13.3421617752326	0.00938119467848971	0.17882902355871
GO:0004300	enoyl-CoA hydratase activity	2/254	12/18639	0.166666666666667	12.2303149606299	0.0111569655133654	0.200169087151556
GO:0097371	MDM2/MDM4 family protein binding	2/254	12/18639	0.166666666666667	12.2303149606299	0.0111569655133654	0.200169087151556
GO:0055106	ubiquitin-protein transferase regulator activity	3/254	36/18639	0.0833333333333333	6.11515748031496	0.0128197799516389	0.215444780686524
GO:0017154	semaphorin receptor activity	2/254	13/18639	0.153846153846154	11.2895215021199	0.0130679621072154	0.215444780686524
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	2/254	13/18639	0.153846153846154	11.2895215021199	0.0130679621072154	0.215444780686524
GO:0019955	cytokine binding	6/254	144/18639	0.0416666666666667	3.05757874015748	0.0141521580748822	0.227179379623109
GO:0031404	chloride ion binding	2/254	14/18639	0.142857142857143	10.4831271091114	0.0151101990716745	0.236339011121063
GO:0005518	collagen binding	4/254	72/18639	0.0555555555555556	4.07677165354331	0.0168185899776751	0.245131674566309
GO:0004129	cytochrome-c oxidase activity	2/254	15/18639	0.133333333333333	9.78425196850394	0.0172797737809037	0.245131674566309
GO:0015116	sulfate transmembrane transporter activity	2/254	15/18639	0.133333333333333	9.78425196850394	0.0172797737809037	0.245131674566309
GO:0048531	beta-1,3-galactosyltransferase activity	2/254	15/18639	0.133333333333333	9.78425196850394	0.0172797737809037	0.245131674566309
GO:0000062	fatty-acyl-CoA binding	2/254	16/18639	0.125	9.17273622047244	0.0195728648706243	0.265321057135129
GO:0016675	oxidoreductase activity, acting on a heme group of donors	2/254	16/18639	0.125	9.17273622047244	0.0195728648706243	0.265321057135129
GO:0019199	transmembrane receptor protein kinase activity	4/254	78/18639	0.0512820512820513	3.76317383403998	0.0219022337107735	0.280183521403871
GO:1901567	fatty acid derivative binding	2/254	17/18639	0.117647058823529	8.63316350162112	0.0219857307624359	0.280183521403871
GO:0003714	transcription corepressor activity	7/254	204/18639	0.0343137254901961	2.51800602130616	0.0220472279137473	0.280183521403871
GO:0035615	clathrin adaptor activity	2/254	18/18639	0.111111111111111	8.15354330708661	0.0245147082130113	0.302067844765997
GO:0001618	virus receptor activity	4/254	81/18639	0.0493827160493827	3.62379702537183	0.0247596594070489	0.302067844765997
GO:0140272	exogenous protein binding	4/254	82/18639	0.0487804878048781	3.57960437872095	0.0257597627608937	0.306764604472941
GO:0008381	mechanosensitive monoatomic ion channel activity	2/254	19/18639	0.105263157894737	7.7244094488189	0.0271562108877685	0.306764604472941
GO:0030506	ankyrin binding	2/254	19/18639	0.105263157894737	7.7244094488189	0.0271562108877685	0.306764604472941
GO:0120227	acyl-CoA binding	2/254	19/18639	0.105263157894737	7.7244094488189	0.0271562108877685	0.306764604472941
GO:0005021	vascular endothelial growth factor receptor activity	3/254	51/18639	0.0588235294117647	4.31658175081056	0.0322411995009173	0.356880747545174
GO:0140312	cargo adaptor activity	2/254	21/18639	0.0952380952380952	6.98875140607424	0.0327628227254586	0.356880747545174
GO:0051087	protein-folding chaperone binding	5/254	134/18639	0.0373134328358209	2.7381302150664	0.0366336245403514	0.392044052098497
GO:0019838	growth factor binding	5/254	136/18639	0.0367647058823529	2.6978635942566	0.0386572703290525	0.39350902754256
GO:0098632	cell-cell adhesion mediator activity	3/254	55/18639	0.0545454545454545	4.00264853256979	0.0390539731908584	0.39350902754256
GO:0042562	hormone binding	4/254	94/18639	0.0425531914893617	3.12263360696934	0.0396539873482838	0.39350902754256
GO:0016922	nuclear receptor binding	5/254	137/18639	0.0364963503649635	2.67817115926203	0.0396942252793577	0.39350902754256
GO:0045296	cadherin binding	9/254	334/18639	0.0269461077844311	1.97735631100005	0.0400800900259682	0.39350902754256
GO:0003779	actin binding	11/254	443/18639	0.0248306997742664	1.82212367359272	0.0410395964284287	0.39350902754256
GO:0030295	protein kinase activator activity	5/254	139/18639	0.0359712230215827	2.63963632243811	0.0418186083036603	0.39350902754256
GO:0030215	semaphorin receptor binding	2/254	24/18639	0.0833333333333333	6.11515748031496	0.0419312898201088	0.39350902754256
GO:0016504	peptidase activator activity	3/254	57/18639	0.0526315789473684	3.86220472440945	0.042712664434556	0.394768565228472
GO:0004709	MAP kinase kinase kinase activity	2/254	25/18639	0.08	5.87055118110236	0.0451767639745796	0.411310836186471
GO:0004714	transmembrane receptor protein tyrosine kinase activity	3/254	60/18639	0.05	3.66909448818898	0.0485102813080074	0.422744793420663
GO:0005112	Notch binding	2/254	26/18639	0.0769230769230769	5.64476075105996	0.0485116976056499	0.422744793420663
GO:0050750	low-density lipoprotein particle receptor binding	2/254	26/18639	0.0769230769230769	5.64476075105996	0.0485116976056499	0.422744793420663
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	9/254	349/18639	0.0257879656160458	1.89236965006881	0.0503894732958799	0.432923643809673
GO:0019209	kinase activator activity	5/254	148/18639	0.0337837837837838	2.47911789742498	0.0522170994084854	0.442394869988556
GO:1901682	sulfur compound transmembrane transporter activity	3/254	63/18639	0.0476190476190476	3.49437570303712	0.0546720342675501	0.451536179650494
GO:0051393	alpha-actinin binding	2/254	28/18639	0.0714285714285714	5.24156355455568	0.0554379299988246	0.451536179650494
GO:0031625	ubiquitin protein ligase binding	8/254	302/18639	0.0264900662251656	1.94389111957032	0.0555167433996509	0.451536179650494
GO:0038024	cargo receptor activity	3/254	65/18639	0.0461538461538462	3.38685645063598	0.0589775999482175	0.467587844777812
GO:0043236	laminin binding	2/254	29/18639	0.0689655172413793	5.06081998370893	0.0590233836850681	0.467587844777812
GO:0016500	protein-hormone receptor activity	3/254	67/18639	0.0447761194029851	3.28575625807968	0.063437853565387	0.489836590821343
GO:0050840	extracellular matrix binding	3/254	67/18639	0.0447761194029851	3.28575625807968	0.063437853565387	0.489836590821343
GO:0070325	lipoprotein particle receptor binding	2/254	31/18639	0.0645161290322581	4.73431546863094	0.066424825587363	0.506489295103643
GO:0008378	galactosyltransferase activity	2/254	32/18639	0.0625	4.58636811023622	0.0702353416405471	0.517480089494537
GO:0015106	bicarbonate transmembrane transporter activity	2/254	32/18639	0.0625	4.58636811023622	0.0702353416405471	0.517480089494537
GO:0097110	scaffold protein binding	3/254	70/18639	0.0428571428571429	3.14493813273341	0.0704112252918796	0.517480089494537
GO:0140297	DNA-binding transcription factor binding	11/254	488/18639	0.0225409836065574	1.65409997418356	0.0715046025137298	0.519259613492562
GO:0030296	protein tyrosine kinase activator activity	2/254	33/18639	0.0606060606060606	4.44738725841088	0.0741155059023463	0.527564654104503
GO:0044389	ubiquitin-like protein ligase binding	8/254	322/18639	0.0248447204968944	1.82315254071502	0.0745132370714563	0.527564654104503
GO:0008514	organic anion transmembrane transporter activity	7/254	269/18639	0.0260223048327138	1.90956590463367	0.0759819392073593	0.527564654104503
GO:1990782	protein tyrosine kinase binding	4/254	117/18639	0.0341880341880342	2.50878255602665	0.0761076878052397	0.527564654104503
GO:0008376	acetylgalactosaminyltransferase activity	2/254	34/18639	0.0588235294117647	4.31658175081056	0.0780627300007808	0.535036688769396
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	4/254	122/18639	0.0327868852459016	2.40596359881244	0.0856868446207102	0.555439675723849
GO:0061134	peptidase regulator activity	6/254	226/18639	0.0265486725663717	1.94819176364016	0.0895262977537623	0.555439675723849
GO:0042805	actinin binding	2/254	37/18639	0.0540540540540541	3.96658863587997	0.0902817279173762	0.555439675723849
GO:0019207	kinase regulator activity	7/254	287/18639	0.024390243902439	1.78980218936048	0.0985651262866276	0.555439675723849
GO:0071949	FAD binding	2/254	40/18639	0.05	3.66909448818898	0.103016445829748	0.555439675723849
GO:0001540	amyloid-beta binding	3/254	83/18639	0.036144578313253	2.65235746134143	0.104274437713865	0.555439675723849
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	4/254	132/18639	0.0303030303030303	2.22369362920544	0.106495715085839	0.555439675723849
GO:0140318	protein transporter activity	2/254	41/18639	0.0487804878048781	3.57960437872095	0.107365279869189	0.555439675723849
GO:0048487	beta-tubulin binding	2/254	42/18639	0.0476190476190476	3.49437570303712	0.111762435585921	0.555439675723849
GO:0016209	antioxidant activity	3/254	86/18639	0.0348837209302326	2.55983336385277	0.112856982177024	0.555439675723849
GO:0050660	flavin adenine dinucleotide binding	3/254	86/18639	0.0348837209302326	2.55983336385277	0.112856982177024	0.555439675723849
GO:0044325	transmembrane transporter binding	4/254	136/18639	0.0294117647058824	2.15829087540528	0.115404380111038	0.555439675723849
GO:0008375	acetylglucosaminyltransferase activity	2/254	43/18639	0.0465116279069767	3.4131111518037	0.116205801757208	0.555439675723849
GO:0004197	cysteine-type endopeptidase activity	3/254	88/18639	0.0340909090909091	2.50165533285612	0.118723459032175	0.555439675723849
GO:0033218	amide binding	6/254	247/18639	0.0242914979757085	1.78255602665051	0.1224239888559	0.555439675723849
GO:0004713	protein tyrosine kinase activity	4/254	140/18639	0.0285714285714286	2.09662542182227	0.124628656884375	0.555439675723849
GO:0046915	transition metal ion transmembrane transporter activity	2/254	45/18639	0.0444444444444444	3.26141732283465	0.125222960433663	0.555439675723849
GO:0004935	adrenergic receptor activity	1/254	10/18639	0.1	7.33818897637795	0.128242348512711	0.555439675723849
GO:0005337	nucleoside transmembrane transporter activity	1/254	10/18639	0.1	7.33818897637795	0.128242348512711	0.555439675723849
GO:0005381	iron ion transmembrane transporter activity	1/254	10/18639	0.1	7.33818897637795	0.128242348512711	0.555439675723849
GO:0005522	profilin binding	1/254	10/18639	0.1	7.33818897637795	0.128242348512711	0.555439675723849
GO:0008239	dipeptidyl-peptidase activity	1/254	10/18639	0.1	7.33818897637795	0.128242348512711	0.555439675723849
GO:0016303	1-phosphatidylinositol-3-kinase activity	1/254	10/18639	0.1	7.33818897637795	0.128242348512711	0.555439675723849
GO:0019531	oxalate transmembrane transporter activity	1/254	10/18639	0.1	7.33818897637795	0.128242348512711	0.555439675723849
GO:0019911	structural constituent of myelin sheath	1/254	10/18639	0.1	7.33818897637795	0.128242348512711	0.555439675723849
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/254	10/18639	0.1	7.33818897637795	0.128242348512711	0.555439675723849
GO:0072582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	1/254	10/18639	0.1	7.33818897637795	0.128242348512711	0.555439675723849
GO:0140135	mechanosensitive monoatomic cation channel activity	1/254	10/18639	0.1	7.33818897637795	0.128242348512711	0.555439675723849
GO:0016758	hexosyltransferase activity	5/254	197/18639	0.0253807106598985	1.86248451177105	0.132422836596974	0.555439675723849
GO:0016829	lyase activity	5/254	200/18639	0.025	1.83454724409449	0.138532602354302	0.555439675723849
GO:0004867	serine-type endopeptidase inhibitor activity	3/254	95/18639	0.0315789473684211	2.31732283464567	0.140102171071947	0.555439675723849
GO:0002162	dystroglycan binding	1/254	11/18639	0.0909090909090909	6.67108088761632	0.140128463896133	0.555439675723849
GO:0004016	adenylate cyclase activity	1/254	11/18639	0.0909090909090909	6.67108088761632	0.140128463896133	0.555439675723849
GO:0005114	type II transforming growth factor beta receptor binding	1/254	11/18639	0.0909090909090909	6.67108088761632	0.140128463896133	0.555439675723849
GO:0008199	ferric iron binding	1/254	11/18639	0.0909090909090909	6.67108088761632	0.140128463896133	0.555439675723849
GO:0015217	ADP transmembrane transporter activity	1/254	11/18639	0.0909090909090909	6.67108088761632	0.140128463896133	0.555439675723849
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	1/254	11/18639	0.0909090909090909	6.67108088761632	0.140128463896133	0.555439675723849
GO:0032794	GTPase activating protein binding	1/254	11/18639	0.0909090909090909	6.67108088761632	0.140128463896133	0.555439675723849
GO:0034056	estrogen response element binding	1/254	11/18639	0.0909090909090909	6.67108088761632	0.140128463896133	0.555439675723849
GO:0047676	arachidonate-CoA ligase activity	1/254	11/18639	0.0909090909090909	6.67108088761632	0.140128463896133	0.555439675723849
GO:0048185	activin binding	1/254	11/18639	0.0909090909090909	6.67108088761632	0.140128463896133	0.555439675723849
GO:0050998	nitric-oxide synthase binding	1/254	11/18639	0.0909090909090909	6.67108088761632	0.140128463896133	0.555439675723849
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/254	11/18639	0.0909090909090909	6.67108088761632	0.140128463896133	0.555439675723849
GO:0140537	transcription regulator activator activity	1/254	11/18639	0.0909090909090909	6.67108088761632	0.140128463896133	0.555439675723849
GO:0003712	transcription coregulator activity	10/254	495/18639	0.0202020202020202	1.48246241947029	0.140339198697156	0.555439675723849
GO:0004896	cytokine receptor activity	3/254	96/18639	0.03125	2.29318405511811	0.143256662915408	0.555439675723849
GO:0005004	GPI-linked ephrin receptor activity	2/254	49/18639	0.0408163265306122	2.99517917403182	0.143724143771947	0.555439675723849
GO:0005008	hepatocyte growth factor receptor activity	2/254	49/18639	0.0408163265306122	2.99517917403182	0.143724143771947	0.555439675723849
GO:0005009	insulin receptor activity	2/254	49/18639	0.0408163265306122	2.99517917403182	0.143724143771947	0.555439675723849
GO:0005011	macrophage colony-stimulating factor receptor activity	2/254	49/18639	0.0408163265306122	2.99517917403182	0.143724143771947	0.555439675723849
GO:0005018	platelet-derived growth factor alpha-receptor activity	2/254	49/18639	0.0408163265306122	2.99517917403182	0.143724143771947	0.555439675723849
GO:0005020	stem cell factor receptor activity	2/254	49/18639	0.0408163265306122	2.99517917403182	0.143724143771947	0.555439675723849
GO:0008288	boss receptor activity	2/254	49/18639	0.0408163265306122	2.99517917403182	0.143724143771947	0.555439675723849
GO:0036332	placental growth factor receptor activity	2/254	49/18639	0.0408163265306122	2.99517917403182	0.143724143771947	0.555439675723849
GO:0038062	protein tyrosine kinase collagen receptor activity	2/254	49/18639	0.0408163265306122	2.99517917403182	0.143724143771947	0.555439675723849
GO:0060175	brain-derived neurotrophic factor receptor activity	2/254	49/18639	0.0408163265306122	2.99517917403182	0.143724143771947	0.555439675723849
GO:0060590	ATPase regulator activity	2/254	49/18639	0.0408163265306122	2.99517917403182	0.143724143771947	0.555439675723849
GO:0005006	epidermal growth factor receptor activity	2/254	50/18639	0.04	2.93527559055118	0.148435800960204	0.555439675723849
GO:0005007	fibroblast growth factor receptor activity	2/254	50/18639	0.04	2.93527559055118	0.148435800960204	0.555439675723849
GO:0005017	platelet-derived growth factor receptor activity	2/254	50/18639	0.04	2.93527559055118	0.148435800960204	0.555439675723849
GO:0005019	platelet-derived growth factor beta-receptor activity	2/254	50/18639	0.04	2.93527559055118	0.148435800960204	0.555439675723849
GO:0005165	neurotrophin receptor binding	1/254	12/18639	0.0833333333333333	6.11515748031496	0.151853145567294	0.555439675723849
GO:0008499	N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity	1/254	12/18639	0.0833333333333333	6.11515748031496	0.151853145567294	0.555439675723849
GO:0016840	carbon-nitrogen lyase activity	1/254	12/18639	0.0833333333333333	6.11515748031496	0.151853145567294	0.555439675723849
GO:0017166	vinculin binding	1/254	12/18639	0.0833333333333333	6.11515748031496	0.151853145567294	0.555439675723849
GO:0031543	peptidyl-proline dioxygenase activity	1/254	12/18639	0.0833333333333333	6.11515748031496	0.151853145567294	0.555439675723849
GO:0035014	phosphatidylinositol 3-kinase regulator activity	1/254	12/18639	0.0833333333333333	6.11515748031496	0.151853145567294	0.555439675723849
GO:0035497	cAMP response element binding	1/254	12/18639	0.0833333333333333	6.11515748031496	0.151853145567294	0.555439675723849
GO:0045295	gamma-catenin binding	1/254	12/18639	0.0833333333333333	6.11515748031496	0.151853145567294	0.555439675723849
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	1/254	12/18639	0.0833333333333333	6.11515748031496	0.151853145567294	0.555439675723849
GO:0070679	inositol 1,4,5 trisphosphate binding	1/254	12/18639	0.0833333333333333	6.11515748031496	0.151853145567294	0.555439675723849
GO:0140807	NAD+-protein-glutamate ADP-ribosyltransferase activity	1/254	12/18639	0.0833333333333333	6.11515748031496	0.151853145567294	0.555439675723849
GO:0140822	NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity	1/254	12/18639	0.0833333333333333	6.11515748031496	0.151853145567294	0.555439675723849
GO:0140844	NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity	1/254	12/18639	0.0833333333333333	6.11515748031496	0.151853145567294	0.555439675723849
GO:0140867	NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity	1/254	12/18639	0.0833333333333333	6.11515748031496	0.151853145567294	0.555439675723849
GO:0005010	insulin-like growth factor receptor activity	2/254	51/18639	0.0392156862745098	2.87772116720704	0.15317843775446	0.555439675723849
GO:0005030	neurotrophin receptor activity	2/254	51/18639	0.0392156862745098	2.87772116720704	0.15317843775446	0.555439675723849
GO:0016757	glycosyltransferase activity	6/254	267/18639	0.0224719101123595	1.64903123064673	0.15851743362942	0.555439675723849
GO:0005003	ephrin receptor activity	2/254	53/18639	0.0377358490566038	2.76912791561432	0.16274985320748	0.555439675723849
GO:0005005	transmembrane-ephrin receptor activity	2/254	53/18639	0.0377358490566038	2.76912791561432	0.16274985320748	0.555439675723849
GO:0038064	collagen receptor activity	2/254	53/18639	0.0377358490566038	2.76912791561432	0.16274985320748	0.555439675723849
GO:0140296	general transcription initiation factor binding	2/254	53/18639	0.0377358490566038	2.76912791561432	0.16274985320748	0.555439675723849
GO:1901505	carbohydrate derivative transmembrane transporter activity	2/254	53/18639	0.0377358490566038	2.76912791561432	0.16274985320748	0.555439675723849
GO:0002161	aminoacyl-tRNA editing activity	1/254	13/18639	0.0769230769230769	5.64476075105996	0.163418577522301	0.555439675723849
GO:0031994	insulin-like growth factor I binding	1/254	13/18639	0.0769230769230769	5.64476075105996	0.163418577522301	0.555439675723849
GO:0035673	oligopeptide transmembrane transporter activity	1/254	13/18639	0.0769230769230769	5.64476075105996	0.163418577522301	0.555439675723849
GO:0070123	transforming growth factor beta receptor activity, type III	1/254	13/18639	0.0769230769230769	5.64476075105996	0.163418577522301	0.555439675723849
GO:0070700	BMP receptor binding	1/254	13/18639	0.0769230769230769	5.64476075105996	0.163418577522301	0.555439675723849
GO:0140410	monoatomic cation:bicarbonate symporter activity	1/254	13/18639	0.0769230769230769	5.64476075105996	0.163418577522301	0.555439675723849
GO:0140806	NAD+-protein-aspartate ADP-ribosyltransferase activity	1/254	13/18639	0.0769230769230769	5.64476075105996	0.163418577522301	0.555439675723849
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	2/254	54/18639	0.037037037037037	2.71784776902887	0.167575333848171	0.555439675723849
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	2/254	54/18639	0.037037037037037	2.71784776902887	0.167575333848171	0.555439675723849
GO:0050661	NADP binding	2/254	54/18639	0.037037037037037	2.71784776902887	0.167575333848171	0.555439675723849
GO:0005161	platelet-derived growth factor receptor binding	1/254	14/18639	0.0714285714285714	5.24156355455568	0.174826914326195	0.555439675723849
GO:0005347	ATP transmembrane transporter activity	1/254	14/18639	0.0714285714285714	5.24156355455568	0.174826914326195	0.555439675723849
GO:0005545	1-phosphatidylinositol binding	1/254	14/18639	0.0714285714285714	5.24156355455568	0.174826914326195	0.555439675723849
GO:0008195	phosphatidate phosphatase activity	1/254	14/18639	0.0714285714285714	5.24156355455568	0.174826914326195	0.555439675723849
GO:0015926	glucosidase activity	1/254	14/18639	0.0714285714285714	5.24156355455568	0.174826914326195	0.555439675723849
GO:0016530	metallochaperone activity	1/254	14/18639	0.0714285714285714	5.24156355455568	0.174826914326195	0.555439675723849
GO:0030283	testosterone dehydrogenase [NAD(P)+] activity	1/254	14/18639	0.0714285714285714	5.24156355455568	0.174826914326195	0.555439675723849
GO:0042043	neurexin family protein binding	1/254	14/18639	0.0714285714285714	5.24156355455568	0.174826914326195	0.555439675723849
GO:0071933	Arp2/3 complex binding	1/254	14/18639	0.0714285714285714	5.24156355455568	0.174826914326195	0.555439675723849
GO:1901474	azole transmembrane transporter activity	1/254	14/18639	0.0714285714285714	5.24156355455568	0.174826914326195	0.555439675723849
GO:0008013	beta-catenin binding	3/254	106/18639	0.0283018867924528	2.07684593671074	0.176007523512044	0.556293209027704
GO:0015932	nucleobase-containing compound transmembrane transporter activity	2/254	57/18639	0.0350877192982456	2.5748031496063	0.182191897378541	0.572871429901599
GO:0000774	adenyl-nucleotide exchange factor activity	1/254	15/18639	0.0666666666666667	4.89212598425197	0.186080281508002	0.573277634948894
GO:0004467	long-chain fatty acid-CoA ligase activity	1/254	15/18639	0.0666666666666667	4.89212598425197	0.186080281508002	0.573277634948894
GO:0005041	low-density lipoprotein particle receptor activity	1/254	15/18639	0.0666666666666667	4.89212598425197	0.186080281508002	0.573277634948894
GO:0017081	chloride channel regulator activity	1/254	15/18639	0.0666666666666667	4.89212598425197	0.186080281508002	0.573277634948894
GO:0031593	polyubiquitin modification-dependent protein binding	2/254	59/18639	0.0338983050847458	2.48752168690778	0.192037984965607	0.585067209343758
GO:0036002	pre-mRNA binding	2/254	59/18639	0.0338983050847458	2.48752168690778	0.192037984965607	0.585067209343758
GO:0005201	extracellular matrix structural constituent	4/254	168/18639	0.0238095238095238	1.74718785151856	0.196835303465087	0.585067209343758
GO:0005024	transforming growth factor beta receptor activity	1/254	16/18639	0.0625	4.58636811023622	0.197180775950493	0.585067209343758
GO:0005324	long-chain fatty acid transmembrane transporter activity	1/254	16/18639	0.0625	4.58636811023622	0.197180775950493	0.585067209343758
GO:0015562	efflux transmembrane transporter activity	1/254	16/18639	0.0625	4.58636811023622	0.197180775950493	0.585067209343758
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1/254	16/18639	0.0625	4.58636811023622	0.197180775950493	0.585067209343758
GO:0015291	secondary active transmembrane transporter activity	6/254	287/18639	0.0209059233449477	1.53411616230898	0.198661820854373	0.585067209343758
GO:0015026	coreceptor activity	2/254	61/18639	0.0327868852459016	2.40596359881244	0.201952064874552	0.585067209343758
GO:0016836	hydro-lyase activity	2/254	61/18639	0.0327868852459016	2.40596359881244	0.201952064874552	0.585067209343758
GO:0017124	SH3 domain binding	3/254	115/18639	0.0260869565217391	1.91431016775077	0.20706114215762	0.585067209343758
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	1/254	17/18639	0.0588235294117647	4.31658175081056	0.208130466274747	0.585067209343758
GO:0008484	sulfuric ester hydrolase activity	1/254	17/18639	0.0588235294117647	4.31658175081056	0.208130466274747	0.585067209343758
GO:0015278	intracellularly gated calcium channel activity	1/254	17/18639	0.0588235294117647	4.31658175081056	0.208130466274747	0.585067209343758
GO:0017110	nucleoside diphosphate phosphatase activity	1/254	17/18639	0.0588235294117647	4.31658175081056	0.208130466274747	0.585067209343758
GO:0019198	transmembrane receptor protein phosphatase activity	1/254	17/18639	0.0588235294117647	4.31658175081056	0.208130466274747	0.585067209343758
GO:0030169	low-density lipoprotein particle binding	1/254	17/18639	0.0588235294117647	4.31658175081056	0.208130466274747	0.585067209343758
GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	1/254	17/18639	0.0588235294117647	4.31658175081056	0.208130466274747	0.585067209343758
GO:0070403	NAD+ binding	1/254	17/18639	0.0588235294117647	4.31658175081056	0.208130466274747	0.585067209343758
GO:0015294	solute:monoatomic cation symporter activity	3/254	116/18639	0.0258620689655172	1.89780749389085	0.210586826480072	0.589256716297448
GO:0000900	mRNA regulatory element binding translation repressor activity	1/254	18/18639	0.0555555555555556	4.07677165354331	0.218931393219555	0.596197097606824
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/254	18/18639	0.0555555555555556	4.07677165354331	0.218931393219555	0.596197097606824
GO:0004706	JUN kinase kinase kinase activity	1/254	18/18639	0.0555555555555556	4.07677165354331	0.218931393219555	0.596197097606824
GO:0030228	lipoprotein particle receptor activity	1/254	18/18639	0.0555555555555556	4.07677165354331	0.218931393219555	0.596197097606824
GO:0031690	adrenergic receptor binding	1/254	18/18639	0.0555555555555556	4.07677165354331	0.218931393219555	0.596197097606824
GO:0070064	proline-rich region binding	1/254	18/18639	0.0555555555555556	4.07677165354331	0.218931393219555	0.596197097606824
GO:0004303	estradiol 17-beta-dehydrogenase [NAD(P)+] activity	1/254	19/18639	0.0526315789473684	3.86220472440945	0.229585570015765	0.60890085960703
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/254	19/18639	0.0526315789473684	3.86220472440945	0.229585570015765	0.60890085960703
GO:0005346	purine ribonucleotide transmembrane transporter activity	1/254	19/18639	0.0526315789473684	3.86220472440945	0.229585570015765	0.60890085960703
GO:0005520	insulin-like growth factor binding	1/254	19/18639	0.0526315789473684	3.86220472440945	0.229585570015765	0.60890085960703
GO:0015245	fatty acid transmembrane transporter activity	1/254	19/18639	0.0526315789473684	3.86220472440945	0.229585570015765	0.60890085960703
GO:0042577	lipid phosphatase activity	1/254	19/18639	0.0526315789473684	3.86220472440945	0.229585570015765	0.60890085960703
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	2/254	67/18639	0.0298507462686567	2.19050417205312	0.231996499569209	0.610241414503854
GO:0004674	protein serine/threonine kinase activity	8/254	433/18639	0.0184757505773672	1.35578549217145	0.239638585328771	0.610241414503854
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	1/254	20/18639	0.05	3.66909448818898	0.240094982755615	0.610241414503854
GO:0005326	neurotransmitter transmembrane transporter activity	1/254	20/18639	0.05	3.66909448818898	0.240094982755615	0.610241414503854
GO:0015095	magnesium ion transmembrane transporter activity	1/254	20/18639	0.05	3.66909448818898	0.240094982755615	0.610241414503854
GO:0016408	C-acyltransferase activity	1/254	20/18639	0.05	3.66909448818898	0.240094982755615	0.610241414503854
GO:0016505	peptidase activator activity involved in apoptotic process	1/254	20/18639	0.05	3.66909448818898	0.240094982755615	0.610241414503854
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/254	20/18639	0.05	3.66909448818898	0.240094982755615	0.610241414503854
GO:0030627	pre-mRNA 5'-splice site binding	1/254	20/18639	0.05	3.66909448818898	0.240094982755615	0.610241414503854
GO:0031418	L-ascorbic acid binding	1/254	20/18639	0.05	3.66909448818898	0.240094982755615	0.610241414503854
GO:0061135	endopeptidase regulator activity	4/254	184/18639	0.0217391304347826	1.59525847312564	0.242740106532616	0.612487548424814
GO:0008028	monocarboxylic acid transmembrane transporter activity	2/254	70/18639	0.0285714285714286	2.09662542182227	0.247128434543304	0.612487548424814
GO:0016782	transferase activity, transferring sulphur-containing groups	2/254	70/18639	0.0285714285714286	2.09662542182227	0.247128434543304	0.612487548424814
GO:0042826	histone deacetylase binding	3/254	127/18639	0.0236220472440945	1.73343046686093	0.250138231397955	0.612487548424814
GO:0009975	cyclase activity	1/254	21/18639	0.0476190476190476	3.49437570303712	0.250461590757123	0.612487548424814
GO:0036122	BMP binding	1/254	21/18639	0.0476190476190476	3.49437570303712	0.250461590757123	0.612487548424814
GO:0051010	microtubule plus-end binding	1/254	21/18639	0.0476190476190476	3.49437570303712	0.250461590757123	0.612487548424814
GO:0008234	cysteine-type peptidase activity	4/254	187/18639	0.0213903743315508	1.56966609120384	0.251612762136501	0.612487548424814
GO:0019902	phosphatase binding	4/254	190/18639	0.0210526315789474	1.54488188976378	0.26055307239411	0.612487548424814
GO:0005243	gap junction channel activity	1/254	22/18639	0.0454545454545455	3.33554044380816	0.260687326923611	0.612487548424814
GO:0034062	5'-3' RNA polymerase activity	1/254	22/18639	0.0454545454545455	3.33554044380816	0.260687326923611	0.612487548424814
GO:0061133	endopeptidase activator activity	1/254	22/18639	0.0454545454545455	3.33554044380816	0.260687326923611	0.612487548424814
GO:0097747	RNA polymerase activity	1/254	22/18639	0.0454545454545455	3.33554044380816	0.260687326923611	0.612487548424814
GO:0043539	protein serine/threonine kinase activator activity	2/254	73/18639	0.0273972602739726	2.01046273325423	0.262293484589818	0.612487548424814
GO:0031491	nucleosome binding	2/254	74/18639	0.027027027027027	1.98329431793999	0.267351101789443	0.612487548424814
GO:0048029	monosaccharide binding	2/254	74/18639	0.027027027027027	1.98329431793999	0.267351101789443	0.612487548424814
GO:0019887	protein kinase regulator activity	5/254	255/18639	0.0196078431372549	1.43886058360352	0.268447461614021	0.612487548424814
GO:0005179	hormone activity	3/254	132/18639	0.0227272727272727	1.66777022190408	0.268477262554194	0.612487548424814
GO:0000295	adenine nucleotide transmembrane transporter activity	1/254	23/18639	0.0434782608695652	3.19051694625128	0.27077409809842	0.612487548424814
GO:0003950	NAD+ poly-ADP-ribosyltransferase activity	1/254	23/18639	0.0434782608695652	3.19051694625128	0.27077409809842	0.612487548424814
GO:0004602	glutathione peroxidase activity	1/254	23/18639	0.0434782608695652	3.19051694625128	0.27077409809842	0.612487548424814
GO:0005158	insulin receptor binding	1/254	23/18639	0.0434782608695652	3.19051694625128	0.27077409809842	0.612487548424814
GO:0016849	phosphorus-oxygen lyase activity	1/254	23/18639	0.0434782608695652	3.19051694625128	0.27077409809842	0.612487548424814
GO:0017134	fibroblast growth factor binding	1/254	23/18639	0.0434782608695652	3.19051694625128	0.27077409809842	0.612487548424814
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity	1/254	23/18639	0.0434782608695652	3.19051694625128	0.27077409809842	0.612487548424814
GO:0140103	catalytic activity, acting on a glycoprotein	1/254	23/18639	0.0434782608695652	3.19051694625128	0.27077409809842	0.612487548424814
GO:1990404	NAD+-protein mono-ADP-ribosyltransferase activity	1/254	23/18639	0.0434782608695652	3.19051694625128	0.27077409809842	0.612487548424814
GO:0046873	metal ion transmembrane transporter activity	8/254	450/18639	0.0177777777777778	1.30456692913386	0.272048474561786	0.612487548424814
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity	1/254	24/18639	0.0416666666666667	3.05757874015748	0.280723785414868	0.612487548424814
GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity	1/254	24/18639	0.0416666666666667	3.05757874015748	0.280723785414868	0.612487548424814
GO:0015149	hexose transmembrane transporter activity	1/254	24/18639	0.0416666666666667	3.05757874015748	0.280723785414868	0.612487548424814
GO:0030552	cAMP binding	1/254	24/18639	0.0416666666666667	3.05757874015748	0.280723785414868	0.612487548424814
GO:0042625	ATPase-coupled ion transmembrane transporter activity	1/254	24/18639	0.0416666666666667	3.05757874015748	0.280723785414868	0.612487548424814
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	1/254	24/18639	0.0416666666666667	3.05757874015748	0.280723785414868	0.612487548424814
GO:0046961	proton-transporting ATPase activity, rotational mechanism	1/254	24/18639	0.0416666666666667	3.05757874015748	0.280723785414868	0.612487548424814
GO:0048027	mRNA 5'-UTR binding	1/254	24/18639	0.0416666666666667	3.05757874015748	0.280723785414868	0.612487548424814
GO:0050431	transforming growth factor beta binding	1/254	24/18639	0.0416666666666667	3.05757874015748	0.280723785414868	0.612487548424814
GO:0055056	D-glucose transmembrane transporter activity	1/254	24/18639	0.0416666666666667	3.05757874015748	0.280723785414868	0.612487548424814
GO:0070696	transmembrane receptor protein serine/threonine kinase binding	1/254	24/18639	0.0416666666666667	3.05757874015748	0.280723785414868	0.612487548424814
GO:0140789	histone phosphatase activity	3/254	136/18639	0.0220588235294118	1.61871815655396	0.283258077484023	0.612487548424814
GO:0003707	nuclear steroid receptor activity	1/254	25/18639	0.04	2.93527559055118	0.290538244641547	0.612487548424814
GO:0015645	fatty acid ligase activity	1/254	25/18639	0.04	2.93527559055118	0.290538244641547	0.612487548424814
GO:0015662	P-type ion transporter activity	1/254	25/18639	0.04	2.93527559055118	0.290538244641547	0.612487548424814
GO:0017025	TBP-class protein binding	1/254	25/18639	0.04	2.93527559055118	0.290538244641547	0.612487548424814
GO:0070530	K63-linked polyubiquitin modification-dependent protein binding	1/254	25/18639	0.04	2.93527559055118	0.290538244641547	0.612487548424814
GO:0120515	fatty acid-CoA ligase activity	1/254	25/18639	0.04	2.93527559055118	0.290538244641547	0.612487548424814
GO:0140358	P-type transmembrane transporter activity	1/254	25/18639	0.04	2.93527559055118	0.290538244641547	0.612487548424814
GO:0015370	solute:sodium symporter activity	2/254	79/18639	0.0253164556962025	1.85776936110834	0.292616371269697	0.612487548424814
GO:0016835	carbon-oxygen lyase activity	2/254	79/18639	0.0253164556962025	1.85776936110834	0.292616371269697	0.612487548424814
GO:0000049	tRNA binding	2/254	80/18639	0.025	1.83454724409449	0.297658716862581	0.612487548424814
GO:0004112	cyclic-nucleotide phosphodiesterase activity	1/254	26/18639	0.0384615384615385	2.82238037552998	0.300219306522983	0.612487548424814
GO:0005160	transforming growth factor beta receptor binding	1/254	26/18639	0.0384615384615385	2.82238037552998	0.300219306522983	0.612487548424814
GO:0008198	ferrous iron binding	1/254	26/18639	0.0384615384615385	2.82238037552998	0.300219306522983	0.612487548424814
GO:0015145	monosaccharide transmembrane transporter activity	1/254	26/18639	0.0384615384615385	2.82238037552998	0.300219306522983	0.612487548424814
GO:0015216	purine nucleotide transmembrane transporter activity	1/254	26/18639	0.0384615384615385	2.82238037552998	0.300219306522983	0.612487548424814
GO:0030247	polysaccharide binding	1/254	26/18639	0.0384615384615385	2.82238037552998	0.300219306522983	0.612487548424814
GO:0034237	protein kinase A regulatory subunit binding	1/254	26/18639	0.0384615384615385	2.82238037552998	0.300219306522983	0.612487548424814
GO:0050681	nuclear androgen receptor binding	1/254	26/18639	0.0384615384615385	2.82238037552998	0.300219306522983	0.612487548424814
GO:0052742	phosphatidylinositol kinase activity	1/254	26/18639	0.0384615384615385	2.82238037552998	0.300219306522983	0.612487548424814
GO:0001671	ATPase activator activity	1/254	27/18639	0.037037037037037	2.71784776902887	0.309768777115749	0.615068436736888
GO:0004683	calcium/calmodulin-dependent protein kinase activity	1/254	27/18639	0.037037037037037	2.71784776902887	0.309768777115749	0.615068436736888
GO:0005044	scavenger receptor activity	1/254	27/18639	0.037037037037037	2.71784776902887	0.309768777115749	0.615068436736888
GO:0005385	zinc ion transmembrane transporter activity	1/254	27/18639	0.037037037037037	2.71784776902887	0.309768777115749	0.615068436736888
GO:0008320	protein transmembrane transporter activity	1/254	27/18639	0.037037037037037	2.71784776902887	0.309768777115749	0.615068436736888
GO:0016405	CoA-ligase activity	1/254	27/18639	0.037037037037037	2.71784776902887	0.309768777115749	0.615068436736888
GO:0023026	MHC class II protein complex binding	1/254	27/18639	0.037037037037037	2.71784776902887	0.309768777115749	0.615068436736888
GO:0035255	ionotropic glutamate receptor binding	1/254	27/18639	0.037037037037037	2.71784776902887	0.309768777115749	0.615068436736888
GO:0005096	GTPase activator activity	5/254	271/18639	0.018450184501845	1.35390940523578	0.310559145106494	0.615068436736888
GO:0030165	PDZ domain binding	2/254	83/18639	0.0240963855421687	1.76823830756095	0.31274960393297	0.615904062708257
GO:0019903	protein phosphatase binding	3/254	144/18639	0.0208333333333333	1.52878937007874	0.313000425310754	0.615904062708257
GO:0008194	UDP-glycosyltransferase activity	3/254	145/18639	0.0206896551724138	1.51824599511268	0.316727571256194	0.616154896371039
GO:0051117	ATPase binding	2/254	84/18639	0.0238095238095238	1.74718785151856	0.317765310433102	0.616154896371039
GO:0046875	ephrin receptor binding	1/254	28/18639	0.0357142857142857	2.62078177727784	0.319188438120079	0.616154896371039
GO:0046966	nuclear thyroid hormone receptor binding	1/254	28/18639	0.0357142857142857	2.62078177727784	0.319188438120079	0.616154896371039
GO:0051119	sugar transmembrane transporter activity	1/254	28/18639	0.0357142857142857	2.62078177727784	0.319188438120079	0.616154896371039
GO:0097718	disordered domain specific binding	1/254	28/18639	0.0357142857142857	2.62078177727784	0.319188438120079	0.616154896371039
GO:0015293	symporter activity	3/254	146/18639	0.0205479452054795	1.50784704994068	0.320455552928189	0.616649486707241
GO:0015085	calcium ion transmembrane transporter activity	3/254	147/18639	0.0204081632653061	1.49758958701591	0.324184010573739	0.618434656778694
GO:0003785	actin monomer binding	1/254	29/18639	0.0344827586206897	2.53040999185447	0.328480047207044	0.618434656778694
GO:0004181	metallocarboxypeptidase activity	1/254	29/18639	0.0344827586206897	2.53040999185447	0.328480047207044	0.618434656778694
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	1/254	29/18639	0.0344827586206897	2.53040999185447	0.328480047207044	0.618434656778694
GO:0035250	UDP-galactosyltransferase activity	1/254	29/18639	0.0344827586206897	2.53040999185447	0.328480047207044	0.618434656778694
GO:0097472	cyclin-dependent protein kinase activity	1/254	29/18639	0.0344827586206897	2.53040999185447	0.328480047207044	0.618434656778694
GO:0099604	ligand-gated calcium channel activity	1/254	29/18639	0.0344827586206897	2.53040999185447	0.328480047207044	0.618434656778694
GO:0030246	carbohydrate binding	5/254	280/18639	0.0178571428571429	1.31039088863892	0.334652072275622	0.624132292085523
GO:0005217	intracellularly ligand-gated monoatomic ion channel activity	1/254	30/18639	0.0333333333333333	2.44606299212598	0.337645338341349	0.624132292085523
GO:0015215	nucleotide transmembrane transporter activity	1/254	30/18639	0.0333333333333333	2.44606299212598	0.337645338341349	0.624132292085523
GO:0033612	receptor serine/threonine kinase binding	1/254	30/18639	0.0333333333333333	2.44606299212598	0.337645338341349	0.624132292085523
GO:0048019	receptor antagonist activity	1/254	30/18639	0.0333333333333333	2.44606299212598	0.337645338341349	0.624132292085523
GO:0098918	structural constituent of synapse	1/254	30/18639	0.0333333333333333	2.44606299212598	0.337645338341349	0.624132292085523
GO:0004857	enzyme inhibitor activity	7/254	416/18639	0.0168269230769231	1.23479141429437	0.339694181638429	0.625577718026402
GO:0004726	non-membrane spanning protein tyrosine phosphatase activity	2/254	89/18639	0.0224719101123595	1.64903123064673	0.342702542118234	0.625577718026402
GO:0030946	protein tyrosine phosphatase activity, metal-dependent	2/254	89/18639	0.0224719101123595	1.64903123064673	0.342702542118234	0.625577718026402
GO:0005310	dicarboxylic acid transmembrane transporter activity	1/254	31/18639	0.032258064516129	2.36715773431547	0.346686022099815	0.625577718026402
GO:0005452	solute:inorganic anion antiporter activity	1/254	31/18639	0.032258064516129	2.36715773431547	0.346686022099815	0.625577718026402
GO:0016878	acid-thiol ligase activity	1/254	31/18639	0.032258064516129	2.36715773431547	0.346686022099815	0.625577718026402
GO:0017147	Wnt-protein binding	1/254	31/18639	0.032258064516129	2.36715773431547	0.346686022099815	0.625577718026402
GO:0072349	modified amino acid transmembrane transporter activity	1/254	31/18639	0.032258064516129	2.36715773431547	0.346686022099815	0.625577718026402
GO:0140793	histone H2AXY142 phosphatase activity	2/254	90/18639	0.0222222222222222	1.63070866141732	0.347657125263853	0.625577718026402
GO:0022884	macromolecule transmembrane transporter activity	1/254	32/18639	0.03125	2.29318405511811	0.355603785985598	0.628748723046999
GO:0031369	translation initiation factor binding	1/254	32/18639	0.03125	2.29318405511811	0.355603785985598	0.628748723046999
GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	1/254	32/18639	0.03125	2.29318405511811	0.355603785985598	0.628748723046999
GO:0043425	bHLH transcription factor binding	1/254	32/18639	0.03125	2.29318405511811	0.355603785985598	0.628748723046999
GO:0071813	lipoprotein particle binding	1/254	32/18639	0.03125	2.29318405511811	0.355603785985598	0.628748723046999
GO:0071814	protein-lipid complex binding	1/254	32/18639	0.03125	2.29318405511811	0.355603785985598	0.628748723046999
GO:0140375	immune receptor activity	3/254	156/18639	0.0192307692307692	1.41119018776499	0.357704543351026	0.630635177584179
GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	1/254	33/18639	0.0303030303030303	2.22369362920544	0.364400294738199	0.635097656543719
GO:0019956	chemokine binding	1/254	33/18639	0.0303030303030303	2.22369362920544	0.364400294738199	0.635097656543719
GO:0140311	protein sequestering activity	1/254	33/18639	0.0303030303030303	2.22369362920544	0.364400294738199	0.635097656543719
GO:0140416	transcription regulator inhibitor activity	1/254	33/18639	0.0303030303030303	2.22369362920544	0.364400294738199	0.635097656543719
GO:0099106	ion channel regulator activity	3/254	160/18639	0.01875	1.37591043307087	0.37254223911778	0.646525813323845
GO:0090482	vitamin transmembrane transporter activity	1/254	34/18639	0.0294117647058824	2.15829087540528	0.373077190639333	0.646525813323845
GO:0004866	endopeptidase inhibitor activity	3/254	161/18639	0.0186335403726708	1.36736440553626	0.376242247095814	0.650163656454524
GO:0016229	steroid dehydrogenase activity	1/254	35/18639	0.0285714285714286	2.09662542182227	0.381636093814695	0.655769062611167
GO:0043015	gamma-tubulin binding	1/254	35/18639	0.0285714285714286	2.09662542182227	0.381636093814695	0.655769062611167
GO:0004725	protein tyrosine phosphatase activity	2/254	98/18639	0.0204081632653061	1.49758958701591	0.386800859035018	0.660685675334753
GO:0042626	ATPase-coupled transmembrane transporter activity	2/254	98/18639	0.0204081632653061	1.49758958701591	0.386800859035018	0.660685675334753
GO:0005484	SNAP receptor activity	1/254	36/18639	0.0277777777777778	2.03838582677165	0.390078602531695	0.660685675334753
GO:0016409	palmitoyltransferase activity	1/254	36/18639	0.0277777777777778	2.03838582677165	0.390078602531695	0.660685675334753
GO:0045505	dynein intermediate chain binding	1/254	36/18639	0.0277777777777778	2.03838582677165	0.390078602531695	0.660685675334753
GO:0015103	inorganic anion transmembrane transporter activity	3/254	165/18639	0.0181818181818182	1.33421617752326	0.390995948845649	0.660685675334753
GO:0022829	wide pore channel activity	1/254	37/18639	0.027027027027027	1.98329431793999	0.398406293493204	0.665829695974944
GO:0023023	MHC protein complex binding	1/254	37/18639	0.027027027027027	1.98329431793999	0.398406293493204	0.665829695974944
GO:0030551	cyclic nucleotide binding	1/254	37/18639	0.027027027027027	1.98329431793999	0.398406293493204	0.665829695974944
GO:0043394	proteoglycan binding	1/254	37/18639	0.027027027027027	1.98329431793999	0.398406293493204	0.665829695974944
GO:0016247	channel regulator activity	3/254	168/18639	0.0178571428571429	1.31039088863892	0.402004877554353	0.670008129257254
GO:0030414	peptidase inhibitor activity	3/254	169/18639	0.0177514792899408	1.30263709639845	0.405662375475131	0.672191437663129
GO:0008238	exopeptidase activity	2/254	102/18639	0.0196078431372549	1.43886058360352	0.40599124128654	0.672191437663129
GO:0042887	amide transmembrane transporter activity	1/254	38/18639	0.0263157894736842	1.93110236220472	0.406620722127368	0.672191437663129
GO:0141108	transporter regulator activity	3/254	170/18639	0.0176470588235294	1.29497452524317	0.409313376558147	0.674813945136405
GO:0140030	modification-dependent protein binding	3/254	173/18639	0.0173410404624277	1.27251831960311	0.420224941847965	0.685665327894095
GO:0015144	carbohydrate transmembrane transporter activity	1/254	40/18639	0.025	1.83454724409449	0.422715909464413	0.685665327894095
GO:0030331	nuclear estrogen receptor binding	1/254	40/18639	0.025	1.83454724409449	0.422715909464413	0.685665327894095
GO:0004721	phosphoprotein phosphatase activity	3/254	175/18639	0.0171428571428571	1.25797525309336	0.42746240722124	0.685665327894095
GO:0015631	tubulin binding	6/254	385/18639	0.0155844155844156	1.14361386644851	0.427927912271007	0.685665327894095
GO:0001727	lipid kinase activity	1/254	41/18639	0.024390243902439	1.78980218936048	0.430599675204293	0.685665327894095
GO:0004812	aminoacyl-tRNA ligase activity	1/254	41/18639	0.024390243902439	1.78980218936048	0.430599675204293	0.685665327894095
GO:0008227	G protein-coupled amine receptor activity	1/254	41/18639	0.024390243902439	1.78980218936048	0.430599675204293	0.685665327894095
GO:0016875	ligase activity, forming carbon-oxygen bonds	1/254	41/18639	0.024390243902439	1.78980218936048	0.430599675204293	0.685665327894095
GO:0016877	ligase activity, forming carbon-sulfur bonds	1/254	41/18639	0.024390243902439	1.78980218936048	0.430599675204293	0.685665327894095
GO:0017080	sodium channel regulator activity	1/254	41/18639	0.024390243902439	1.78980218936048	0.430599675204293	0.685665327894095
GO:0042169	SH2 domain binding	1/254	41/18639	0.024390243902439	1.78980218936048	0.430599675204293	0.685665327894095
GO:0042287	MHC protein binding	1/254	41/18639	0.024390243902439	1.78980218936048	0.430599675204293	0.685665327894095
GO:0005496	steroid binding	2/254	108/18639	0.0185185185185185	1.35892388451444	0.434221909653904	0.685665327894095
GO:0043021	ribonucleoprotein complex binding	3/254	177/18639	0.0169491525423729	1.24376084345389	0.434668203488391	0.685665327894095
GO:0004520	DNA endonuclease activity	1/254	42/18639	0.0238095238095238	1.74718785151856	0.438376193243766	0.685665327894095
GO:0008307	structural constituent of muscle	1/254	42/18639	0.0238095238095238	1.74718785151856	0.438376193243766	0.685665327894095
GO:0031492	nucleosomal DNA binding	1/254	42/18639	0.0238095238095238	1.74718785151856	0.438376193243766	0.685665327894095
GO:0035198	miRNA binding	1/254	42/18639	0.0238095238095238	1.74718785151856	0.438376193243766	0.685665327894095
GO:0051879	Hsp90 protein binding	1/254	42/18639	0.0238095238095238	1.74718785151856	0.438376193243766	0.685665327894095
GO:0042277	peptide binding	4/254	249/18639	0.0160642570281124	1.17882553837397	0.441307955394915	0.68848555700997
GO:0008200	ion channel inhibitor activity	1/254	43/18639	0.0232558139534884	1.70655557590185	0.446046916850588	0.691760251507425
GO:0048156	tau protein binding	1/254	43/18639	0.0232558139534884	1.70655557590185	0.446046916850588	0.691760251507425
GO:0001046	core promoter sequence-specific DNA binding	1/254	44/18639	0.0227272727272727	1.66777022190408	0.453613279677	0.691760251507425
GO:0001223	transcription coactivator binding	1/254	44/18639	0.0227272727272727	1.66777022190408	0.453613279677	0.691760251507425
GO:0016248	channel inhibitor activity	1/254	44/18639	0.0227272727272727	1.66777022190408	0.453613279677	0.691760251507425
GO:0019205	nucleobase-containing compound kinase activity	1/254	44/18639	0.0227272727272727	1.66777022190408	0.453613279677	0.691760251507425
GO:0030020	extracellular matrix structural constituent conferring tensile strength	1/254	44/18639	0.0227272727272727	1.66777022190408	0.453613279677	0.691760251507425
GO:0030547	signaling receptor inhibitor activity	1/254	44/18639	0.0227272727272727	1.66777022190408	0.453613279677	0.691760251507425
GO:0043014	alpha-tubulin binding	1/254	44/18639	0.0227272727272727	1.66777022190408	0.453613279677	0.691760251507425
GO:0042605	peptide antigen binding	1/254	45/18639	0.0222222222222222	1.63070866141732	0.46107669602344	0.699643742722135
GO:0141110	transporter inhibitor activity	1/254	45/18639	0.0222222222222222	1.63070866141732	0.46107669602344	0.699643742722135
GO:0003713	transcription coactivator activity	4/254	256/18639	0.015625	1.14659202755906	0.462343381246136	0.699824969131869
GO:0035401	histone H3Y41 kinase activity	2/254	115/18639	0.0173913043478261	1.27620677850051	0.466226921479447	0.70221832617892
GO:0140801	histone H2AXY142 kinase activity	2/254	115/18639	0.0173913043478261	1.27620677850051	0.466226921479447	0.70221832617892
GO:0004180	carboxypeptidase activity	1/254	46/18639	0.0217391304347826	1.59525847312564	0.468438561098735	0.70381163120746
GO:0046943	carboxylic acid transmembrane transporter activity	3/254	188/18639	0.0159574468085106	1.1709876026135	0.473658852986624	0.709906388997151
GO:0001784	phosphotyrosine residue binding	1/254	47/18639	0.0212765957446809	1.56131680348467	0.475700251276809	0.711218512938366
GO:0005342	organic acid transmembrane transporter activity	3/254	189/18639	0.0158730158730159	1.16479190101237	0.477144223930472	0.711633194615129
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	1/254	48/18639	0.0208333333333333	1.52878937007874	0.482863124349942	0.714918703527826
GO:0038187	pattern recognition receptor activity	1/254	48/18639	0.0208333333333333	1.52878937007874	0.482863124349942	0.714918703527826
GO:0140693	molecular condensate scaffold activity	1/254	48/18639	0.0208333333333333	1.52878937007874	0.482863124349942	0.714918703527826
GO:0016763	pentosyltransferase activity	1/254	49/18639	0.0204081632653061	1.49758958701591	0.48992851977865	0.721875355229412
GO:0035254	glutamate receptor binding	1/254	49/18639	0.0204081632653061	1.49758958701591	0.48992851977865	0.721875355229412
GO:0015108	chloride transmembrane transporter activity	2/254	121/18639	0.0165289256198347	1.21292379774842	0.492793948324419	0.722606510764172
GO:0051082	unfolded protein binding	2/254	121/18639	0.0165289256198347	1.21292379774842	0.492793948324419	0.722606510764172
GO:0015605	organophosphate ester transmembrane transporter activity	1/254	50/18639	0.02	1.46763779527559	0.49689775893821	0.726876817631435
GO:0016830	carbon-carbon lyase activity	1/254	51/18639	0.0196078431372549	1.43886058360352	0.503772145361885	0.735169877202751
GO:0005080	protein kinase C binding	1/254	52/18639	0.0192307692307692	1.41119018776499	0.510552964980891	0.740650954648594
GO:0030159	signaling receptor complex adaptor activity	1/254	52/18639	0.0192307692307692	1.41119018776499	0.510552964980891	0.740650954648594
GO:0016791	phosphatase activity	4/254	273/18639	0.0146520146520147	1.07519252401142	0.512187639168715	0.740650954648594
GO:0004864	protein phosphatase inhibitor activity	1/254	53/18639	0.0188679245283019	1.38456395780716	0.517241486361149	0.740650954648594
GO:0005246	calcium channel regulator activity	1/254	53/18639	0.0188679245283019	1.38456395780716	0.517241486361149	0.740650954648594
GO:0005544	calcium-dependent phospholipid binding	1/254	53/18639	0.0188679245283019	1.38456395780716	0.517241486361149	0.740650954648594
GO:0017046	peptide hormone binding	1/254	53/18639	0.0188679245283019	1.38456395780716	0.517241486361149	0.740650954648594
GO:0051018	protein kinase A binding	1/254	53/18639	0.0188679245283019	1.38456395780716	0.517241486361149	0.740650954648594
GO:0001217	DNA-binding transcription repressor activity	4/254	278/18639	0.0143884892086331	1.05585452897525	0.526451768068999	0.752073954384284
GO:0008374	O-acyltransferase activity	1/254	55/18639	0.0181818181818182	1.33421617752326	0.530346623240984	0.75334466748588
GO:0140313	molecular sequestering activity	1/254	55/18639	0.0181818181818182	1.33421617752326	0.530346623240984	0.75334466748588
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	2/254	130/18639	0.0153846153846154	1.12895215021199	0.531046241014637	0.75334466748588
GO:0005262	calcium channel activity	2/254	131/18639	0.0152671755725191	1.12033419486686	0.535174153840474	0.754317118945927
GO:0019212	phosphatase inhibitor activity	1/254	56/18639	0.0178571428571429	1.31039088863892	0.536765691132546	0.754317118945927
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	1/254	56/18639	0.0178571428571429	1.31039088863892	0.536765691132546	0.754317118945927
GO:0170055	lipid transmembrane transporter activity	1/254	56/18639	0.0178571428571429	1.31039088863892	0.536765691132546	0.754317118945927
GO:0005516	calmodulin binding	3/254	207/18639	0.0144927536231884	1.06350564875043	0.537914666789309	0.754317118945927
GO:0031267	small GTPase binding	4/254	283/18639	0.0141342756183746	1.03719985531844	0.540513473439007	0.75469262698688
GO:0004601	peroxidase activity	1/254	57/18639	0.0175438596491228	1.28740157480315	0.54309736602101	0.75469262698688
GO:0051015	actin filament binding	3/254	209/18639	0.0143540669856459	1.05332856120258	0.544418283417543	0.75469262698688
GO:0106310	protein serine kinase activity	5/254	361/18639	0.0138504155124654	1.01636966431828	0.547980540597062	0.75469262698688
GO:0061980	regulatory RNA binding	1/254	58/18639	0.0172413793103448	1.26520499592723	0.549342833087562	0.75469262698688
GO:0015297	antiporter activity	2/254	135/18639	0.0148148148148148	1.08713910761155	0.551436096080986	0.75469262698688
GO:0042578	phosphoric ester hydrolase activity	5/254	363/18639	0.0137741046831956	1.01076983145702	0.552901522067052	0.75469262698688
GO:0002020	protease binding	2/254	136/18639	0.0147058823529412	1.07914543770264	0.555438753074971	0.75469262698688
GO:0016779	nucleotidyltransferase activity	2/254	136/18639	0.0147058823529412	1.07914543770264	0.555438753074971	0.75469262698688
GO:0001786	phosphatidylserine binding	1/254	59/18639	0.0169491525423729	1.24376084345389	0.555503261503458	0.75469262698688
GO:0004879	nuclear receptor activity	1/254	59/18639	0.0169491525423729	1.24376084345389	0.555503261503458	0.75469262698688
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	1/254	59/18639	0.0169491525423729	1.24376084345389	0.555503261503458	0.75469262698688
GO:0045309	protein phosphorylated amino acid binding	1/254	59/18639	0.0169491525423729	1.24376084345389	0.555503261503458	0.75469262698688
GO:0070888	E-box binding	1/254	59/18639	0.0169491525423729	1.24376084345389	0.555503261503458	0.75469262698688
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	1/254	60/18639	0.0166666666666667	1.22303149606299	0.561579804645445	0.757884249632127
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	1/254	60/18639	0.0166666666666667	1.22303149606299	0.561579804645445	0.757884249632127
GO:0098531	ligand-modulated transcription factor activity	1/254	60/18639	0.0166666666666667	1.22303149606299	0.561579804645445	0.757884249632127
GO:0019905	syntaxin binding	1/254	61/18639	0.0163934426229508	1.20298179940622	0.567573600308293	0.764282331540968
GO:0004536	DNA nuclease activity	1/254	64/18639	0.015625	1.14659202755906	0.585069651023746	0.786106799833667
GO:0008235	metalloexopeptidase activity	1/254	66/18639	0.0151515151515152	1.11184681460272	0.596340124699293	0.799488958388063
GO:0008509	monoatomic anion transmembrane transporter activity	2/254	149/18639	0.0134228187919463	0.984991808909792	0.605159004111636	0.808856854990699
GO:0030145	manganese ion binding	1/254	68/18639	0.0147058823529412	1.07914543770264	0.607305638665148	0.808856854990699
GO:1990841	promoter-specific chromatin binding	1/254	68/18639	0.0147058823529412	1.07914543770264	0.607305638665148	0.808856854990699
GO:0000287	magnesium ion binding	3/254	230/18639	0.0130434782608696	0.957155083875385	0.609375907215457	0.809845976909431
GO:0098960	postsynaptic neurotransmitter receptor activity	1/254	69/18639	0.0144927536231884	1.06350564875043	0.612676613183432	0.812462465308464
GO:0005125	cytokine activity	3/254	234/18639	0.0128205128205128	0.940793458509994	0.621029309107146	0.821752448059347
GO:0005506	iron ion binding	2/254	154/18639	0.012987012987013	0.95301155537376	0.623132701950397	0.822750970107668
GO:0051020	GTPase binding	4/254	315/18639	0.0126984126984127	0.931833520809899	0.625092900530331	0.823556521217067
GO:0022836	gated channel activity	4/254	318/18639	0.0125786163522013	0.923042638538107	0.632501551706136	0.831521436510222
GO:0003684	damaged DNA binding	1/254	74/18639	0.0135135135135135	0.991647158969994	0.638453524198779	0.835743883607844
GO:0035064	methylated histone binding	1/254	74/18639	0.0135135135135135	0.991647158969994	0.638453524198779	0.835743883607844
GO:0019003	GDP binding	1/254	75/18639	0.0133333333333333	0.978425196850394	0.643400079806293	0.837902131430701
GO:0044183	protein folding chaperone	1/254	75/18639	0.0133333333333333	0.978425196850394	0.643400079806293	0.837902131430701
GO:0140034	methylation-dependent protein binding	1/254	76/18639	0.0131578947368421	0.965551181102362	0.648279221140553	0.837902131430701
GO:0004175	endopeptidase activity	5/254	405/18639	0.0123456790123457	0.905949256342957	0.649643339282444	0.837902131430701
GO:0008083	growth factor activity	2/254	162/18639	0.0123456790123457	0.905949256342957	0.650568877663018	0.837902131430701
GO:0003724	RNA helicase activity	1/254	77/18639	0.012987012987013	0.95301155537376	0.653091863376738	0.837902131430701
GO:0015081	sodium ion transmembrane transporter activity	2/254	164/18639	0.0121951219512195	0.894901094680238	0.657175887959274	0.837902131430701
GO:0140713	histone chaperone activity	2/254	164/18639	0.0121951219512195	0.894901094680238	0.657175887959274	0.837902131430701
GO:0042393	histone binding	3/254	247/18639	0.0121457489878543	0.891278013325257	0.657254493318034	0.837902131430701
GO:0030695	GTPase regulator activity	6/254	489/18639	0.0122699386503067	0.900391285445148	0.658993716882145	0.837902131430701
GO:0060589	nucleoside-triphosphatase regulator activity	6/254	490/18639	0.0122448979591837	0.898553752209545	0.66092375231866	0.837902131430701
GO:0008186	ATP-dependent activity, acting on RNA	1/254	79/18639	0.0126582278481013	0.928884680554171	0.662521249546148	0.837902131430701
GO:0140104	molecular carrier activity	3/254	249/18639	0.0120481927710843	0.884119153780476	0.66260197183152	0.837902131430701
GO:0016874	ligase activity	2/254	167/18639	0.0119760479041916	0.878825027111132	0.666899268137291	0.837902131430701
GO:0048306	calcium-dependent protein binding	1/254	80/18639	0.0125	0.917273622047244	0.667139762618092	0.837902131430701
GO:0033192	calmodulin-dependent protein phosphatase activity	1/254	81/18639	0.0123456790123457	0.905949256342957	0.671695315196086	0.837902131430701
GO:0140791	histone H2AXS140 phosphatase activity	1/254	81/18639	0.0123456790123457	0.905949256342957	0.671695315196086	0.837902131430701
GO:0180004	RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity	1/254	81/18639	0.0123456790123457	0.905949256342957	0.671695315196086	0.837902131430701
GO:0180005	RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity	1/254	81/18639	0.0123456790123457	0.905949256342957	0.671695315196086	0.837902131430701
GO:0180006	RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity	1/254	81/18639	0.0123456790123457	0.905949256342957	0.671695315196086	0.837902131430701
GO:0180007	RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity	1/254	81/18639	0.0123456790123457	0.905949256342957	0.671695315196086	0.837902131430701
GO:0180008	RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity	1/254	81/18639	0.0123456790123457	0.905949256342957	0.671695315196086	0.837902131430701
GO:1990439	MAP kinase serine/threonine phosphatase activity	1/254	81/18639	0.0123456790123457	0.905949256342957	0.671695315196086	0.837902131430701
GO:0008420	RNA polymerase II CTD heptapeptide repeat phosphatase activity	1/254	82/18639	0.0121951219512195	0.894901094680238	0.676188762223794	0.84007157832284
GO:0033549	MAP kinase phosphatase activity	1/254	82/18639	0.0121951219512195	0.894901094680238	0.676188762223794	0.84007157832284
GO:0004723	calcium-dependent protein serine/threonine phosphatase activity	1/254	83/18639	0.0120481927710843	0.884119153780476	0.680620947080999	0.840442869877347
GO:0005254	chloride channel activity	1/254	83/18639	0.0120481927710843	0.884119153780476	0.680620947080999	0.840442869877347
GO:0008135	translation factor activity, RNA binding	1/254	83/18639	0.0120481927710843	0.884119153780476	0.680620947080999	0.840442869877347
GO:0017018	myosin phosphatase activity	1/254	84/18639	0.0119047619047619	0.87359392575928	0.684992701739408	0.842430540445642
GO:0180051	translation factor activity	1/254	84/18639	0.0119047619047619	0.87359392575928	0.684992701739408	0.842430540445642
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	1/254	86/18639	0.0116279069767442	0.853277787950925	0.693558192226432	0.851248485428821
GO:0003730	mRNA 3'-UTR binding	3/254	262/18639	0.0114503816793893	0.840250646150147	0.695889673516864	0.852394981617042
GO:0008081	phosphoric diester hydrolase activity	1/254	87/18639	0.0114942528735632	0.843469997284822	0.697753536331132	0.852965244813608
GO:0003727	single-stranded RNA binding	1/254	89/18639	0.0112359550561798	0.824515615323365	0.705973361688319	0.86128750125975
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	3/254	268/18639	0.0111940298507463	0.82143906451992	0.710396946921095	0.861581377692281
GO:0141003	histone H2AX kinase activity	4/254	354/18639	0.0112994350282486	0.829173895635927	0.713907982823183	0.861581377692281
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	1/254	91/18639	0.010989010989011	0.806394393008566	0.71397049877682	0.861581377692281
GO:0072341	modified amino acid binding	1/254	91/18639	0.010989010989011	0.806394393008566	0.71397049877682	0.861581377692281
GO:0008237	metallopeptidase activity	2/254	184/18639	0.0108695652173913	0.797629236562821	0.717854692880507	0.861581377692281
GO:0043178	alcohol binding	1/254	92/18639	0.0108695652173913	0.797629236562821	0.717887443639376	0.861581377692281
GO:0052689	carboxylic ester hydrolase activity	1/254	92/18639	0.0108695652173913	0.797629236562821	0.717887443639376	0.861581377692281
GO:0140996	histone H3 kinase activity	4/254	357/18639	0.0112044817927171	0.82220604777344	0.720058016369329	0.861581377692281
GO:1901981	phosphatidylinositol phosphate binding	2/254	185/18639	0.0108108108108108	0.793317727175995	0.720638453799738	0.861581377692281
GO:0051213	dioxygenase activity	1/254	93/18639	0.010752688172043	0.789052578105156	0.721750957378288	0.861581377692281
GO:0051219	phosphoprotein binding	1/254	93/18639	0.010752688172043	0.789052578105156	0.721750957378288	0.861581377692281
GO:0035173	histone kinase activity	4/254	360/18639	0.0111111111111111	0.815354330708661	0.726110493520247	0.864043050934005
GO:0005126	cytokine receptor binding	3/254	275/18639	0.0109090909090909	0.800529706513958	0.726646041195319	0.864043050934005
GO:0140597	protein carrier chaperone	2/254	188/18639	0.0106382978723404	0.780658401742335	0.72885162792681	0.864979558434542
GO:0016407	acetyltransferase activity	1/254	96/18639	0.0104166666666667	0.76439468503937	0.733028122987235	0.867621756059901
GO:0005216	monoatomic ion channel activity	5/254	448/18639	0.0111607142857143	0.818994305399325	0.733922665781817	0.867621756059901
GO:0030594	neurotransmitter receptor activity	1/254	97/18639	0.0103092783505155	0.756514327461645	0.736685074762096	0.869202892852763
GO:0046982	protein heterodimerization activity	4/254	369/18639	0.010840108401084	0.795467639715767	0.743685328560189	0.875768437107558
GO:0035091	phosphatidylinositol binding	3/254	284/18639	0.0105633802816901	0.775160807363868	0.746483526206399	0.876709884300465
GO:0043130	ubiquitin binding	1/254	100/18639	0.01	0.733818897637795	0.747359245633183	0.876709884300465
GO:0015171	amino acid transmembrane transporter activity	1/254	102/18639	0.00980392156862745	0.71943029180176	0.754234790362127	0.883077201767557
GO:0004722	protein serine/threonine phosphatase activity	1/254	103/18639	0.00970873786407767	0.71244553168718	0.757602345157834	0.883627974275867
GO:0005253	monoatomic anion channel activity	1/254	103/18639	0.00970873786407767	0.71244553168718	0.757602345157834	0.883627974275867
GO:0000149	SNARE binding	1/254	106/18639	0.00943396226415094	0.69228197890358	0.767431715916534	0.893384249444821
GO:0019888	protein phosphatase regulator activity	1/254	107/18639	0.00934579439252336	0.685812053867098	0.770619129943254	0.895386036695972
GO:0004222	metalloendopeptidase activity	1/254	110/18639	0.00909090909090909	0.667108088761632	0.77992264237842	0.904473026332388
GO:1902936	phosphatidylinositol bisphosphate binding	1/254	111/18639	0.00900900900900901	0.661098105979996	0.782939515865164	0.906248775479602
GO:0005200	structural constituent of cytoskeleton	1/254	112/18639	0.00892857142857143	0.65519544431946	0.785915193918394	0.906253815293422
GO:0043022	ribosome binding	1/254	112/18639	0.00892857142857143	0.65519544431946	0.785915193918394	0.906253815293422
GO:0001221	transcription coregulator binding	1/254	115/18639	0.00869565217391304	0.638103389250257	0.794600620929445	0.914540337296153
GO:0019208	phosphatase regulator activity	1/254	117/18639	0.00854700854700855	0.627195639006663	0.800195000694672	0.916015712255543
GO:0032182	ubiquitin-like protein binding	1/254	120/18639	0.00833333333333333	0.611515748031496	0.80830325371987	0.916015712255543
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	2/254	229/18639	0.00873362445414847	0.640889866932572	0.821953791438386	0.916015712255543
GO:0005085	guanyl-nucleotide exchange factor activity	2/254	230/18639	0.00869565217391304	0.638103389250257	0.823818509721043	0.916015712255543
GO:0004519	endonuclease activity	1/254	127/18639	0.0078740157480315	0.577810155620311	0.825970486793323	0.916015712255543
GO:0019783	ubiquitin-like protein peptidase activity	1/254	127/18639	0.0078740157480315	0.577810155620311	0.825970486793323	0.916015712255543
GO:0031490	chromatin DNA binding	1/254	128/18639	0.0078125	0.573296013779528	0.828358316112386	0.916015712255543
GO:0140994	RNA polymerase II CTD heptapeptide repeat modifying activity	1/254	128/18639	0.0078125	0.573296013779528	0.828358316112386	0.916015712255543
GO:0035591	signaling adaptor activity	1/254	129/18639	0.00775193798449612	0.56885185863395	0.830713509657168	0.916015712255543
GO:0003924	GTPase activity	3/254	331/18639	0.00906344410876133	0.665092656469301	0.832033649956134	0.916015712255543
GO:0016798	hydrolase activity, acting on glycosyl bonds	1/254	130/18639	0.00769230769230769	0.564476075105996	0.833036511739668	0.916015712255543
GO:0031072	heat shock protein binding	1/254	131/18639	0.00763358778625954	0.560167097433432	0.835327760646585	0.916015712255543
GO:0099094	ligand-gated monoatomic cation channel activity	1/254	136/18639	0.00735294117647059	0.53957271885132	0.84632263597413	0.916015712255543
GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity	2/254	243/18639	0.00823045267489712	0.603966170895305	0.846514222921832	0.916015712255543
GO:0005261	monoatomic cation channel activity	3/254	341/18639	0.00879765395894428	0.645588472995128	0.846670032136182	0.916015712255543
GO:0004676	3-phosphoinositide-dependent protein kinase activity	2/254	245/18639	0.00816326530612245	0.599035834806363	0.849761207848359	0.916015712255543
GO:0004711	ribosomal protein S6 kinase activity	2/254	245/18639	0.00816326530612245	0.599035834806363	0.849761207848359	0.916015712255543
GO:0035175	histone H3S10 kinase activity	2/254	245/18639	0.00816326530612245	0.599035834806363	0.849761207848359	0.916015712255543
GO:0035979	histone H2AXS139 kinase activity	2/254	245/18639	0.00816326530612245	0.599035834806363	0.849761207848359	0.916015712255543
GO:0044022	histone H3S28 kinase activity	2/254	245/18639	0.00816326530612245	0.599035834806363	0.849761207848359	0.916015712255543
GO:0044023	histone H4S1 kinase activity	2/254	245/18639	0.00816326530612245	0.599035834806363	0.849761207848359	0.916015712255543
GO:0044024	histone H2AS1 kinase activity	2/254	245/18639	0.00816326530612245	0.599035834806363	0.849761207848359	0.916015712255543
GO:0044025	histone H2BS14 kinase activity	2/254	245/18639	0.00816326530612245	0.599035834806363	0.849761207848359	0.916015712255543
GO:0072354	histone H3T3 kinase activity	2/254	245/18639	0.00816326530612245	0.599035834806363	0.849761207848359	0.916015712255543
GO:0072371	histone H2AS121 kinase activity	2/254	245/18639	0.00816326530612245	0.599035834806363	0.849761207848359	0.916015712255543
GO:0072518	Rho-dependent protein serine/threonine kinase activity	2/254	245/18639	0.00816326530612245	0.599035834806363	0.849761207848359	0.916015712255543
GO:0140823	histone H2BS36 kinase activity	2/254	245/18639	0.00816326530612245	0.599035834806363	0.849761207848359	0.916015712255543
GO:0140855	histone H3S57 kinase activity	2/254	245/18639	0.00816326530612245	0.599035834806363	0.849761207848359	0.916015712255543
GO:0140995	histone H2A kinase activity	2/254	245/18639	0.00816326530612245	0.599035834806363	0.849761207848359	0.916015712255543
GO:0140997	histone H4 kinase activity	2/254	245/18639	0.00816326530612245	0.599035834806363	0.849761207848359	0.916015712255543
GO:0140998	histone H2B kinase activity	2/254	245/18639	0.00816326530612245	0.599035834806363	0.849761207848359	0.916015712255543
GO:1990244	histone H2AT120 kinase activity	2/254	245/18639	0.00816326530612245	0.599035834806363	0.849761207848359	0.916015712255543
GO:0004677	DNA-dependent protein kinase activity	2/254	246/18639	0.00813008130081301	0.596600729786826	0.851361233154107	0.916015712255543
GO:0140857	histone H3T45 kinase activity	2/254	246/18639	0.00813008130081301	0.596600729786826	0.851361233154107	0.916015712255543
GO:0070851	growth factor receptor binding	1/254	139/18639	0.00719424460431655	0.527927264487623	0.852565307093944	0.916015712255543
GO:0140101	catalytic activity, acting on a tRNA	1/254	139/18639	0.00719424460431655	0.527927264487623	0.852565307093944	0.916015712255543
GO:0035402	histone H3T11 kinase activity	2/254	247/18639	0.00809716599190283	0.594185342216838	0.852945777969096	0.916015712255543
GO:0035403	histone H3T6 kinase activity	2/254	247/18639	0.00809716599190283	0.594185342216838	0.852945777969096	0.916015712255543
GO:0004679	AMP-activated protein kinase activity	2/254	248/18639	0.00806451612903226	0.591789433578867	0.854514964953703	0.916088099511
GO:0020037	heme binding	1/254	142/18639	0.00704225352112676	0.516773871575912	0.85855534672284	0.918804844738478
GO:0019842	vitamin binding	1/254	150/18639	0.00666666666666667	0.489212598425197	0.873369864325225	0.925369284537501
GO:0000510	H3-H4 histone complex chaperone activity	1/254	151/18639	0.00662251655629139	0.48597277989258	0.875109496239411	0.925369284537501
GO:0140584	chromatin extrusion motor activity	1/254	151/18639	0.00662251655629139	0.48597277989258	0.875109496239411	0.925369284537501
GO:0140665	ATP-dependent H3-H4 histone complex chaperone activity	1/254	151/18639	0.00662251655629139	0.48597277989258	0.875109496239411	0.925369284537501
GO:0140849	ATP-dependent H2AZ histone chaperone activity	1/254	151/18639	0.00662251655629139	0.48597277989258	0.875109496239411	0.925369284537501
GO:0015616	DNA translocase activity	1/254	152/18639	0.00657894736842105	0.482775590551181	0.87682532206996	0.925369284537501
GO:0046906	tetrapyrrole binding	1/254	152/18639	0.00657894736842105	0.482775590551181	0.87682532206996	0.925369284537501
GO:0140674	ATP-dependent histone chaperone activity	1/254	152/18639	0.00657894736842105	0.482775590551181	0.87682532206996	0.925369284537501
GO:0061775	cohesin loader activity	1/254	153/18639	0.0065359477124183	0.479620194534507	0.878517666322366	0.925554018059833
GO:0004386	helicase activity	1/254	155/18639	0.00645161290322581	0.473431546863094	0.881833186143894	0.927445247496165
GO:0140658	ATP-dependent chromatin remodeler activity	1/254	158/18639	0.00632911392405063	0.464442340277086	0.886638216493289	0.93089382454545
GO:0003689	DNA clamp loader activity	1/254	160/18639	0.00625	0.458636811023622	0.889732939934375	0.932442591292066
GO:0005525	GTP binding	3/254	378/18639	0.00793650793650794	0.582395950506187	0.891617351558581	0.932442591292066
GO:0008017	microtubule binding	2/254	276/18639	0.0072463768115942	0.531752824375214	0.892699136581257	0.932442591292066
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	4/254	484/18639	0.00826446280991736	0.606461898874211	0.899213871815057	0.935970739841935
GO:0140098	catalytic activity, acting on RNA	3/254	387/18639	0.00775193798449612	0.56885185863395	0.90059927975716	0.935970739841935
GO:0001216	DNA-binding transcription activator activity	4/254	491/18639	0.00814663951120163	0.597815802556249	0.905206843242404	0.935970739841935
GO:0005244	voltage-gated monoatomic ion channel activity	1/254	173/18639	0.00578034682080925	0.424172773201038	0.90789606922412	0.935970739841935
GO:0003823	antigen binding	1/254	174/18639	0.00574712643678161	0.421734998642411	0.909162959639861	0.935970739841935
GO:0005543	phospholipid binding	4/254	497/18639	0.00804828973843058	0.590598710372471	0.910091549661573	0.935970739841935
GO:0022832	voltage-gated channel activity	1/254	175/18639	0.00571428571428571	0.419325084364454	0.910412491632901	0.935970739841935
GO:0004252	serine-type endopeptidase activity	1/254	176/18639	0.00568181818181818	0.41694255547602	0.911644902114121	0.935970739841935
GO:0019001	guanyl nucleotide binding	3/254	400/18639	0.0075	0.550364173228346	0.912394610179337	0.935970739841935
GO:0032561	guanyl ribonucleotide binding	3/254	400/18639	0.0075	0.550364173228346	0.912394610179337	0.935970739841935
GO:0005319	lipid transporter activity	1/254	178/18639	0.00561797752808989	0.412257807661683	0.914059290124512	0.935970739841935
GO:0001664	G protein-coupled receptor binding	2/254	297/18639	0.00673400673400673	0.494154139823431	0.915002841578885	0.935970739841935
GO:0016853	isomerase activity	1/254	180/18639	0.00555555555555556	0.407677165354331	0.916407955324099	0.935970739841935
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	1/254	181/18639	0.00552486187845304	0.405424805324749	0.917558200697504	0.935970739841935
GO:0015276	ligand-gated monoatomic ion channel activity	1/254	186/18639	0.00537634408602151	0.394526289052578	0.923077196471061	0.936962326061292
GO:0031406	carboxylic acid binding	1/254	187/18639	0.0053475935828877	0.39241652280096	0.924136015746861	0.936962326061292
GO:0022834	ligand-gated channel activity	1/254	188/18639	0.00531914893617021	0.390329200871168	0.925180317286006	0.936962326061292
GO:0016887	ATP hydrolysis activity	3/254	417/18639	0.00719424460431655	0.527927264487623	0.925905199077454	0.936962326061292
GO:0043177	organic acid binding	1/254	189/18639	0.00529100529100529	0.388263967004124	0.926210299368785	0.936962326061292
GO:0008236	serine-type peptidase activity	1/254	194/18639	0.00515463917525773	0.378257163730822	0.931152170957549	0.940402026960439
GO:0017171	serine hydrolase activity	1/254	198/18639	0.00505050505050505	0.370615604867573	0.934867172076136	0.942593347051971
GO:0004518	nuclease activity	1/254	209/18639	0.00478468899521531	0.351109520400859	0.944085502476778	0.948475640584611
GO:0008094	ATP-dependent activity, acting on DNA	1/254	210/18639	0.00476190476190476	0.349437570303712	0.944856109225064	0.948475640584611
GO:0140097	catalytic activity, acting on DNA	2/254	336/18639	0.00595238095238095	0.43679696287964	0.945365884385973	0.948475640584611
GO:0045182	translation regulator activity	2/254	356/18639	0.00561797752808989	0.412257807661683	0.95662400518906	0.958194816363426
GO:0030371	translation repressor activity	1/254	329/18639	0.00303951367781155	0.223045257640667	0.989482309602162	0.989482309602162