ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0140097 catalytic activity, acting on DNA 98/2651 336/18639 0.291666666666667 2.05068841946435 7.45397531604549e-13 9.81688549123192e-10 GO:0003678 DNA helicase activity 36/2651 74/18639 0.486486486486487 3.42045327107568 1.68094286050124e-12 1.10690087364007e-09 GO:0008094 ATP-dependent activity, acting on DNA 66/2651 210/18639 0.314285714285714 2.20972139893302 1.28917780312622e-10 5.6594905557241e-08 GO:0003684 damaged DNA binding 33/2651 74/18639 0.445945945945946 3.13541549848604 2.63986584837843e-10 8.69175830578599e-08 GO:0003735 structural constituent of ribosome 57/2651 175/18639 0.325714285714286 2.29007490434876 5.1064810017733e-10 1.20074616317637e-07 GO:0017116 single-stranded DNA helicase activity 28/2651 58/18639 0.482758620689655 3.39424290118238 6.20200482205176e-10 1.20074616317637e-07 GO:0045296 cadherin binding 90/2651 334/18639 0.269461077844311 1.89456244056587 6.38209805788505e-10 1.20074616317637e-07 GO:0016887 ATP hydrolysis activity 103/2651 417/18639 0.247002398081535 1.73665699654535 6.90950689489612e-09 1.03314642135299e-06 GO:0000217 DNA secondary structure binding 21/2651 39/18639 0.538461538461538 3.78588631285727 7.06022611402953e-09 1.03314642135299e-06 GO:0000400 four-way junction DNA binding 13/2651 18/18639 0.722222222222222 5.07789513391173 4.02748425440381e-08 5.30419676304982e-06 GO:0003697 single-stranded DNA binding 40/2651 121/18639 0.330578512396694 2.32427495004224 1.19037693806296e-07 1.4252058431172e-05 GO:0004386 helicase activity 46/2651 155/18639 0.296774193548387 2.0865990922476 5.08737182061862e-07 5.58339057312894e-05 GO:0009378 four-way junction helicase activity 21/2651 48/18639 0.4375 3.07603262919653 6.928821346364e-07 6.5180412236867e-05 GO:0036121 double-stranded DNA helicase activity 21/2651 48/18639 0.4375 3.07603262919653 6.928821346364e-07 6.5180412236867e-05 GO:0061749 forked DNA-dependent helicase activity 20/2651 47/18639 0.425531914893617 2.99188583994799 2.16700526591649e-06 0.000190263062347468 GO:0098631 cell adhesion mediator activity 27/2651 76/18639 0.355263157894737 2.49783100716711 2.76066817459716e-06 0.000227237499121529 GO:0043138 3'-5' DNA helicase activity 20/2651 48/18639 0.416666666666667 2.92955488494908 3.219950359688e-06 0.000248473583428911 GO:0003689 DNA clamp loader activity 45/2651 160/18639 0.28125 1.97744954734063 3.39599430654549e-06 0.000248473583428911 GO:0019838 growth factor binding 39/2651 136/18639 0.286764705882353 2.01622306787672 9.00912545490109e-06 0.000602360064372834 GO:0098632 cell-cell adhesion mediator activity 21/2651 55/18639 0.381818181818182 2.68453756729879 9.58902611085598e-06 0.000602360064372834 GO:1990518 single-stranded 3'-5' DNA helicase activity 19/2651 47/18639 0.404255319148936 2.84229154795059 9.6048301836215e-06 0.000602360064372834 GO:0008017 microtubule binding 65/2651 276/18639 0.235507246376812 1.65583536975383 2.08584543580699e-05 0.00124866292679901 GO:0003779 actin binding 94/2651 443/18639 0.212189616252822 1.49189070438942 3.38711332735017e-05 0.00193949054440007 GO:0070064 proline-rich region binding 10/2651 18/18639 0.555555555555556 3.9060731799321 4.8690329393882e-05 0.00256500655246971 GO:0098641 cadherin binding involved in cell-cell adhesion 10/2651 18/18639 0.555555555555556 3.9060731799321 4.8690329393882e-05 0.00256500655246971 GO:0030695 GTPase regulator activity 101/2651 489/18639 0.206543967280164 1.45219653192568 5.45975965264101e-05 0.00276557825481854 GO:0060589 nucleoside-triphosphatase regulator activity 101/2651 490/18639 0.206122448979592 1.44923286553399 5.93467241505495e-05 0.00288216631906653 GO:0003714 transcription corepressor activity 50/2651 204/18639 0.245098039215686 1.72326757938181 6.12761252345199e-05 0.00288216631906653 GO:0140658 ATP-dependent chromatin remodeler activity 41/2651 158/18639 0.259493670886076 1.82448228277841 7.06287352177264e-05 0.00320751876833606 GO:0051020 GTPase binding 70/2651 315/18639 0.222222222222222 1.56242927197284 7.52989542860981e-05 0.00330562409315971 GO:0003712 transcription coregulator activity 101/2651 495/18639 0.204040404040404 1.43459414972052 8.93566169248958e-05 0.00379621498355122 GO:0032356 oxidized DNA binding 7/2651 10/18639 0.7 4.92165220671445 9.43647664753886e-05 0.00388369992025271 GO:0003688 DNA replication origin binding 9/2651 16/18639 0.5625 3.95489909468125 0.000104020670016274 0.00415137037610401 GO:0017154 semaphorin receptor activity 8/2651 13/18639 0.615384615384615 4.32672721469402 0.000109138049653504 0.00417541667611727 GO:0005178 integrin binding 41/2651 161/18639 0.254658385093168 1.79048571850304 0.000110963996707748 0.00417541667611727 GO:0042393 histone binding 57/2651 247/18639 0.230769230769231 1.62252270551026 0.000117469686242432 0.00429743268836897 GO:0004536 DNA nuclease activity 21/2651 64/18639 0.328125 2.3070244718974 0.000129672378998086 0.00461563576055348 GO:0015616 DNA translocase activity 39/2651 152/18639 0.256578947368421 1.8039890607318 0.000135774328868925 0.00470565239790458 GO:0061775 cohesin loader activity 39/2651 153/18639 0.254901960784314 1.79219828255708 0.000157597587456972 0.00532194929950852 GO:0038024 cargo receptor activity 21/2651 65/18639 0.323076923076923 2.27153178771436 0.00016615435566545 0.00547063216028494 GO:0031625 ubiquitin protein ligase binding 66/2651 302/18639 0.218543046357616 1.53656123766865 0.000197936796232289 0.00635811611312013 GO:0019205 nucleobase-containing compound kinase activity 16/2651 44/18639 0.363636363636364 2.55670244504647 0.000212375229901471 0.00662619705975425 GO:0035173 histone kinase activity 76/2651 360/18639 0.211111111111111 1.4843078083742 0.000216345082436927 0.00662619705975425 GO:1990948 ubiquitin ligase inhibitor activity 7/2651 11/18639 0.636363636363636 4.47422927883132 0.000227499361908193 0.00676169708827281 GO:0106310 protein serine kinase activity 76/2651 361/18639 0.210526315789474 1.48019615239532 0.000236605519847361 0.00676169708827281 GO:0000510 H3-H4 histone complex chaperone activity 38/2651 151/18639 0.251655629139073 1.76937354640633 0.000251574151348039 0.00676169708827281 GO:0140584 chromatin extrusion motor activity 38/2651 151/18639 0.251655629139073 1.76937354640633 0.000251574151348039 0.00676169708827281 GO:0140665 ATP-dependent H3-H4 histone complex chaperone activity 38/2651 151/18639 0.251655629139073 1.76937354640633 0.000251574151348039 0.00676169708827281 GO:0140849 ATP-dependent H2AZ histone chaperone activity 38/2651 151/18639 0.251655629139073 1.76937354640633 0.000251574151348039 0.00676169708827281 GO:0044389 ubiquitin-like protein ligase binding 69/2651 322/18639 0.214285714285714 1.50662822654524 0.00026351430444738 0.006940966779144 GO:0031267 small GTPase binding 62/2651 283/18639 0.219081272084806 1.54034546600856 0.000283209072066426 0.00731345780218594 GO:0140674 ATP-dependent histone chaperone activity 38/2651 152/18639 0.25 1.75773293096945 0.000290174092174411 0.0073492169114173 GO:0140713 histone chaperone activity 40/2651 164/18639 0.24390243902439 1.71486139606775 0.000353544756869734 0.0087852536754234 GO:0019199 transmembrane receptor protein kinase activity 23/2651 78/18639 0.294871794871795 2.07322345704088 0.000378632000755869 0.00923441379621258 GO:0004725 protein tyrosine phosphatase activity 27/2651 98/18639 0.275510204081633 1.93709343412959 0.000416007766981681 0.00996149507481589 GO:0140996 histone H3 kinase activity 74/2651 357/18639 0.207282913165266 1.45739200999147 0.00045824023451221 0.0107768283723675 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 25/2651 89/18639 0.280898876404494 1.97498082131398 0.000487879919610518 0.0110782388642595 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 25/2651 89/18639 0.280898876404494 1.97498082131398 0.000487879919610518 0.0110782388642595 GO:0008381 mechanosensitive monoatomic ion channel activity 9/2651 19/18639 0.473684210526316 3.33044134288948 0.000560685003265004 0.0125156296491527 GO:0141003 histone H2AX kinase activity 73/2651 354/18639 0.206214689265537 1.44988140068666 0.000581819482004709 0.0126436506693343 GO:0140793 histone H2AXY142 phosphatase activity 25/2651 90/18639 0.277777777777778 1.95303658996605 0.000585620873826418 0.0126436506693343 GO:0015631 tubulin binding 78/2651 385/18639 0.202597402597403 1.42444850509732 0.000668527894274403 0.0140966351180653 GO:0001618 virus receptor activity 23/2651 81/18639 0.283950617283951 1.99643740307641 0.000683022428407064 0.0140966351180653 GO:0016853 isomerase activity 42/2651 180/18639 0.233333333333333 1.64055073557148 0.000685030104446606 0.0140966351180653 GO:0005159 insulin-like growth factor receptor binding 8/2651 16/18639 0.5 3.51546586193889 0.000731923567617936 0.0148298975161973 GO:0140272 exogenous protein binding 23/2651 82/18639 0.280487804878049 1.97209060547791 0.000823446330137224 0.0164314972241019 GO:0140664 ATP-dependent DNA damage sensor activity 9/2651 20/18639 0.45 3.163919275745 0.00089137391232698 0.0172970137918133 GO:0005542 folic acid binding 7/2651 13/18639 0.538461538461538 3.78588631285727 0.000910121491247029 0.0172970137918133 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 7/2651 13/18639 0.538461538461538 3.78588631285727 0.000910121491247029 0.0172970137918133 GO:0140597 protein carrier chaperone 43/2651 188/18639 0.228723404255319 1.60813863897205 0.000919355326823791 0.0172970137918133 GO:0140612 DNA damage sensor activity 10/2651 24/18639 0.416666666666667 2.92955488494908 0.000965407962839974 0.017907637845919 GO:0004674 protein serine/threonine kinase activity 85/2651 433/18639 0.196304849884527 1.38020599660418 0.00108474515878485 0.0198417968627729 GO:0004714 transmembrane receptor protein tyrosine kinase activity 18/2651 60/18639 0.3 2.10927951716333 0.00126639684221058 0.0228471868656347 GO:0016895 DNA exonuclease activity, producing 5'-phosphomonoesters 10/2651 25/18639 0.4 2.81237268955111 0.00140560431125324 0.0250159578097367 GO:0051015 actin filament binding 46/2651 209/18639 0.220095693779904 1.54747779568602 0.0014616663130334 0.0256668604568665 GO:0140104 molecular carrier activity 53/2651 249/18639 0.21285140562249 1.49654370026314 0.0014942173218697 0.0258932133276631 GO:0008013 beta-catenin binding 27/2651 106/18639 0.254716981132075 1.79089770325189 0.00153123155606003 0.0261900254458579 GO:0042813 Wnt receptor activity 7/2651 14/18639 0.5 3.51546586193889 0.00159740364326828 0.0269715461305682 GO:0090482 vitamin transmembrane transporter activity 12/2651 34/18639 0.352941176470588 2.48150531430981 0.00174221965592927 0.0290443454032766 GO:0035615 clathrin adaptor activity 8/2651 18/18639 0.444444444444444 3.12485854394568 0.00190946534366913 0.0311298349513489 GO:0140857 histone H3T45 kinase activity 52/2651 246/18639 0.211382113821138 1.48621320992538 0.00192499909337796 0.0311298349513489 GO:1901681 sulfur compound binding 57/2651 275/18639 0.207272727272727 1.45732039367649 0.00193822814427533 0.0311298349513489 GO:0004529 DNA exonuclease activity 10/2651 26/18639 0.384615384615385 2.70420450918376 0.00199582338973626 0.0313179448501786 GO:0032404 mismatch repair complex binding 6/2651 11/18639 0.545454545454545 3.8350536675697 0.00199749989932802 0.0313179448501786 GO:0004713 protein tyrosine kinase activity 33/2651 140/18639 0.235714285714286 1.65729104919976 0.00203686204068909 0.0315593800892651 GO:0033218 amide binding 52/2651 247/18639 0.210526315789474 1.48019615239532 0.00210835435682104 0.0319161228498081 GO:0035403 histone H3T6 kinase activity 52/2651 247/18639 0.210526315789474 1.48019615239532 0.00210835435682104 0.0319161228498081 GO:0000287 magnesium ion binding 49/2651 230/18639 0.21304347826087 1.49789414986961 0.00215626210222331 0.0322704225980466 GO:0004679 AMP-activated protein kinase activity 52/2651 248/18639 0.209677419354839 1.47422761952276 0.00230676727311297 0.0341349718953907 GO:0003777 microtubule motor activity 19/2651 68/18639 0.279411764705882 1.96452504049526 0.00236687950995963 0.0342547287320531 GO:1990841 promoter-specific chromatin binding 19/2651 68/18639 0.279411764705882 1.96452504049526 0.00236687950995963 0.0342547287320531 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 51/2651 243/18639 0.209876543209877 1.47562764575213 0.00247311292409788 0.0344189919042744 GO:0017147 Wnt-protein binding 11/2651 31/18639 0.354838709677419 2.49484674073083 0.00255871325460007 0.0344189919042744 GO:0055105 ubiquitin-protein transferase inhibitor activity 7/2651 15/18639 0.466666666666667 3.28110147114297 0.00262940622716305 0.0344189919042744 GO:0120227 acyl-CoA binding 8/2651 19/18639 0.421052631578947 2.96039230479064 0.00289039650032668 0.0344189919042744 GO:0051539 4 iron, 4 sulfur cluster binding 14/2651 45/18639 0.311111111111111 2.18740098076198 0.00292776644343114 0.0344189919042744 GO:0004676 3-phosphoinositide-dependent protein kinase activity 51/2651 245/18639 0.208163265306122 1.4635817057868 0.00295318609353303 0.0344189919042744 GO:0004711 ribosomal protein S6 kinase activity 51/2651 245/18639 0.208163265306122 1.4635817057868 0.00295318609353303 0.0344189919042744 GO:0035175 histone H3S10 kinase activity 51/2651 245/18639 0.208163265306122 1.4635817057868 0.00295318609353303 0.0344189919042744 GO:0035979 histone H2AXS139 kinase activity 51/2651 245/18639 0.208163265306122 1.4635817057868 0.00295318609353303 0.0344189919042744 GO:0044022 histone H3S28 kinase activity 51/2651 245/18639 0.208163265306122 1.4635817057868 0.00295318609353303 0.0344189919042744 GO:0044023 histone H4S1 kinase activity 51/2651 245/18639 0.208163265306122 1.4635817057868 0.00295318609353303 0.0344189919042744 GO:0044024 histone H2AS1 kinase activity 51/2651 245/18639 0.208163265306122 1.4635817057868 0.00295318609353303 0.0344189919042744 GO:0044025 histone H2BS14 kinase activity 51/2651 245/18639 0.208163265306122 1.4635817057868 0.00295318609353303 0.0344189919042744 GO:0072354 histone H3T3 kinase activity 51/2651 245/18639 0.208163265306122 1.4635817057868 0.00295318609353303 0.0344189919042744 GO:0072371 histone H2AS121 kinase activity 51/2651 245/18639 0.208163265306122 1.4635817057868 0.00295318609353303 0.0344189919042744 GO:0072518 Rho-dependent protein serine/threonine kinase activity 51/2651 245/18639 0.208163265306122 1.4635817057868 0.00295318609353303 0.0344189919042744 GO:0140823 histone H2BS36 kinase activity 51/2651 245/18639 0.208163265306122 1.4635817057868 0.00295318609353303 0.0344189919042744 GO:0140855 histone H3S57 kinase activity 51/2651 245/18639 0.208163265306122 1.4635817057868 0.00295318609353303 0.0344189919042744 GO:0140995 histone H2A kinase activity 51/2651 245/18639 0.208163265306122 1.4635817057868 0.00295318609353303 0.0344189919042744 GO:0140997 histone H4 kinase activity 51/2651 245/18639 0.208163265306122 1.4635817057868 0.00295318609353303 0.0344189919042744 GO:0140998 histone H2B kinase activity 51/2651 245/18639 0.208163265306122 1.4635817057868 0.00295318609353303 0.0344189919042744 GO:1990244 histone H2AT120 kinase activity 51/2651 245/18639 0.208163265306122 1.4635817057868 0.00295318609353303 0.0344189919042744 GO:0004677 DNA-dependent protein kinase activity 51/2651 246/18639 0.207317073170732 1.45763218665759 0.00322209653972742 0.037223694235272 GO:0019842 vitamin binding 34/2651 150/18639 0.226666666666667 1.5936778574123 0.00347330752062417 0.0397769217796698 GO:0035402 histone H3T11 kinase activity 51/2651 247/18639 0.206477732793522 1.45173084177234 0.00351189680160613 0.0398721386872007 GO:0005096 GTPase activator activity 55/2651 271/18639 0.202952029520295 1.42694186277962 0.00368644047335603 0.0414960863539307 GO:0045499 chemorepellent activity 10/2651 28/18639 0.357142857142857 2.51104704424207 0.00376746510502361 0.0416953911203033 GO:0097718 disordered domain specific binding 10/2651 28/18639 0.357142857142857 2.51104704424207 0.00376746510502361 0.0416953911203033 GO:0005021 vascular endothelial growth factor receptor activity 15/2651 51/18639 0.294117647058824 2.06792109525817 0.00385738489781781 0.0423347992535504 GO:0140299 molecular sensor activity 19/2651 71/18639 0.267605633802817 1.88151694019265 0.00401931301273901 0.0437473986593164 GO:0030215 semaphorin receptor binding 9/2651 24/18639 0.375 2.63659939645417 0.00406694279467682 0.043902980824503 GO:0000062 fatty-acyl-CoA binding 7/2651 16/18639 0.4375 3.07603262919653 0.00410522607347592 0.0439559572257543 GO:0003713 transcription coactivator activity 52/2651 256/18639 0.203125 1.42815800641267 0.00456772038296375 0.0485136108416391 GO:0005518 collagen binding 19/2651 72/18639 0.263888888888889 1.85538476046775 0.00474696645361932 0.0500140385553331 GO:0050840 extracellular matrix binding 18/2651 67/18639 0.26865671641791 1.88890703029552 0.00481346193088704 0.0500680941791626 GO:0003774 cytoskeletal motor activity 34/2651 153/18639 0.222222222222222 1.56242927197284 0.00482813057004833 0.0500680941791626 GO:0042887 amide transmembrane transporter activity 12/2651 38/18639 0.315789473684211 2.22029422859298 0.00498498848899994 0.051290858125101 GO:0043236 laminin binding 10/2651 29/18639 0.344827586206897 2.42445921513027 0.00502827775275273 0.0513352077548477 GO:0019207 kinase regulator activity 57/2651 287/18639 0.198606271777003 1.39638713679803 0.00510911750978354 0.0517592904644994 GO:1901505 carbohydrate derivative transmembrane transporter activity 15/2651 53/18639 0.283018867924528 1.98988633694654 0.00573657258300603 0.0569373660852487 GO:0031994 insulin-like growth factor I binding 6/2651 13/18639 0.461538461538462 3.24504541102051 0.00574993901999854 0.0569373660852487 GO:0140666 annealing activity 6/2651 13/18639 0.461538461538462 3.24504541102051 0.00574993901999854 0.0569373660852487 GO:0070182 DNA polymerase binding 8/2651 21/18639 0.380952380952381 2.67845018052487 0.00598231698870352 0.058360825734241 GO:0140312 cargo adaptor activity 8/2651 21/18639 0.380952380952381 2.67845018052487 0.00598231698870352 0.058360825734241 GO:1901567 fatty acid derivative binding 7/2651 17/18639 0.411764705882353 2.89508953336144 0.00613129064517614 0.059374336615419 GO:0016776 phosphotransferase activity, phosphate group as acceptor 12/2651 39/18639 0.307692307692308 2.16336360734701 0.00628566240193652 0.0604249444040175 GO:0140030 modification-dependent protein binding 37/2651 173/18639 0.213872832369942 1.50372528198542 0.00655186980646798 0.0625276270660749 GO:0019887 protein kinase regulator activity 51/2651 255/18639 0.2 1.40618634477556 0.00674959975905024 0.0639512437602098 GO:0140463 chromatin-protein adaptor activity 15/2651 54/18639 0.277777777777778 1.95303658996605 0.00692022624823832 0.0650995569209276 GO:0022804 active transmembrane transporter activity 84/2651 457/18639 0.183807439824945 1.29233755974996 0.00740209869978835 0.0691235019607754 GO:0050750 low-density lipoprotein particle receptor binding 9/2651 26/18639 0.346153846153846 2.43378405826539 0.00745295161612005 0.0691235019607754 GO:0005345 purine nucleobase transmembrane transporter activity 5/2651 10/18639 0.5 3.51546586193889 0.00782927037749357 0.0712980297046259 GO:0008353 RNA polymerase II CTD heptapeptide repeat kinase activity 5/2651 10/18639 0.5 3.51546586193889 0.00782927037749357 0.0712980297046259 GO:0097110 scaffold protein binding 18/2651 70/18639 0.257142857142857 1.80795387185429 0.00784982103809473 0.0712980297046259 GO:0019843 rRNA binding 17/2651 65/18639 0.261538461538462 1.83885906624496 0.0080569382492903 0.072677997769283 GO:0005006 epidermal growth factor receptor activity 14/2651 50/18639 0.28 1.96866088268578 0.00827710074932204 0.0731606824621284 GO:0005017 platelet-derived growth factor receptor activity 14/2651 50/18639 0.28 1.96866088268578 0.00827710074932204 0.0731606824621284 GO:0005019 platelet-derived growth factor beta-receptor activity 14/2651 50/18639 0.28 1.96866088268578 0.00827710074932204 0.0731606824621284 GO:0000900 mRNA regulatory element binding translation repressor activity 7/2651 18/18639 0.388888888888889 2.73425122595247 0.00881790674613516 0.0768048454454169 GO:0030983 mismatched DNA binding 6/2651 14/18639 0.428571428571429 3.01325645309048 0.00886434055254621 0.0768048454454169 GO:0061665 SUMO ligase activity 6/2651 14/18639 0.428571428571429 3.01325645309048 0.00886434055254621 0.0768048454454169 GO:0055106 ubiquitin-protein transferase regulator activity 11/2651 36/18639 0.305555555555556 2.14834024896266 0.00924046044742961 0.0795404340474823 GO:0015026 coreceptor activity 16/2651 61/18639 0.262295081967213 1.8441788128204 0.00969442267243931 0.0823888879614012 GO:0005085 guanyl-nucleotide exchange factor activity 46/2651 230/18639 0.2 1.40618634477556 0.00969649023084068 0.0823888879614012 GO:0005010 insulin-like growth factor receptor activity 14/2651 51/18639 0.274509803921569 1.93005968890763 0.00994942566610745 0.0839961128350225 GO:0051540 metal cluster binding 19/2651 77/18639 0.246753246753247 1.73490523056724 0.010184545263495 0.0854334147262606 GO:0030165 PDZ domain binding 20/2651 83/18639 0.240963855421687 1.69420041539224 0.0111525013109343 0.0929610394082307 GO:0004520 DNA endonuclease activity 12/2651 42/18639 0.285714285714286 2.00883763539365 0.0118382065548431 0.0980560882561534 GO:0043539 protein serine/threonine kinase activator activity 18/2651 73/18639 0.246575342465753 1.73365439766849 0.0122678151842505 0.0997962526605083 GO:0005346 purine ribonucleotide transmembrane transporter activity 7/2651 19/18639 0.368421052631579 2.59034326669181 0.0122756210561901 0.0997962526605083 GO:0008574 plus-end-directed microtubule motor activity 7/2651 19/18639 0.368421052631579 2.59034326669181 0.0122756210561901 0.0997962526605083 GO:0019789 SUMO transferase activity 9/2651 28/18639 0.321428571428571 2.25994233981786 0.0126489882643297 0.100671790282806 GO:0015205 nucleobase transmembrane transporter activity 5/2651 11/18639 0.454545454545455 3.19587805630808 0.0126890791092982 0.100671790282806 GO:0019215 intermediate filament binding 5/2651 11/18639 0.454545454545455 3.19587805630808 0.0126890791092982 0.100671790282806 GO:0048407 platelet-derived growth factor binding 5/2651 11/18639 0.454545454545455 3.19587805630808 0.0126890791092982 0.100671790282806 GO:0004721 phosphoprotein phosphatase activity 36/2651 175/18639 0.205714285714286 1.44636309748343 0.013346259878545 0.105251642275711 GO:0031491 nucleosome binding 18/2651 74/18639 0.243243243243243 1.71022663553784 0.0141127093897776 0.110496524647208 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 13/2651 48/18639 0.270833333333333 1.9042106752169 0.0143012879842364 0.110496524647208 GO:0016879 ligase activity, forming carbon-nitrogen bonds 13/2651 48/18639 0.270833333333333 1.9042106752169 0.0143012879842364 0.110496524647208 GO:0048156 tau protein binding 12/2651 43/18639 0.27906976744186 1.96212048108217 0.0143469291683163 0.110496524647208 GO:0048027 mRNA 5'-UTR binding 8/2651 24/18639 0.333333333333333 2.34364390795926 0.0146105330051472 0.111225849524733 GO:0050699 WW domain binding 8/2651 24/18639 0.333333333333333 2.34364390795926 0.0146105330051472 0.111225849524733 GO:0002039 p53 binding 17/2651 69/18639 0.246376811594203 1.73225854066554 0.0147937231067082 0.111973180066291 GO:0051861 glycolipid binding 9/2651 29/18639 0.310344827586207 2.18201329361724 0.0160783079945394 0.119709276544358 GO:0019209 kinase activator activity 31/2651 148/18639 0.209459459459459 1.47269515837981 0.016085290086144 0.119709276544358 GO:0051287 NAD binding 14/2651 54/18639 0.259259259259259 1.82283415063498 0.0165847786237278 0.119709276544358 GO:0005004 GPI-linked ephrin receptor activity 13/2651 49/18639 0.26530612244898 1.86534923286553 0.0169974447333295 0.119709276544358 GO:0005008 hepatocyte growth factor receptor activity 13/2651 49/18639 0.26530612244898 1.86534923286553 0.0169974447333295 0.119709276544358 GO:0005009 insulin receptor activity 13/2651 49/18639 0.26530612244898 1.86534923286553 0.0169974447333295 0.119709276544358 GO:0005011 macrophage colony-stimulating factor receptor activity 13/2651 49/18639 0.26530612244898 1.86534923286553 0.0169974447333295 0.119709276544358 GO:0005018 platelet-derived growth factor alpha-receptor activity 13/2651 49/18639 0.26530612244898 1.86534923286553 0.0169974447333295 0.119709276544358 GO:0005020 stem cell factor receptor activity 13/2651 49/18639 0.26530612244898 1.86534923286553 0.0169974447333295 0.119709276544358 GO:0008288 boss receptor activity 13/2651 49/18639 0.26530612244898 1.86534923286553 0.0169974447333295 0.119709276544358 GO:0036332 placental growth factor receptor activity 13/2651 49/18639 0.26530612244898 1.86534923286553 0.0169974447333295 0.119709276544358 GO:0038062 protein tyrosine kinase collagen receptor activity 13/2651 49/18639 0.26530612244898 1.86534923286553 0.0169974447333295 0.119709276544358 GO:0060175 brain-derived neurotrophic factor receptor activity 13/2651 49/18639 0.26530612244898 1.86534923286553 0.0169974447333295 0.119709276544358 GO:0051536 iron-sulfur cluster binding 18/2651 76/18639 0.236842105263158 1.66522067144474 0.0184490554837306 0.129241521659964 GO:0008483 transaminase activity 8/2651 25/18639 0.32 2.24989815164089 0.0188677505644623 0.130621634865613 GO:0051082 unfolded protein binding 26/2651 121/18639 0.214876033057851 1.51077871752746 0.0190715029364916 0.130621634865613 GO:0003995 acyl-CoA dehydrogenase activity 5/2651 12/18639 0.416666666666667 2.92955488494908 0.01924115198476 0.130621634865613 GO:0031543 peptidyl-proline dioxygenase activity 5/2651 12/18639 0.416666666666667 2.92955488494908 0.01924115198476 0.130621634865613 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 5/2651 12/18639 0.416666666666667 2.92955488494908 0.01924115198476 0.130621634865613 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 5/2651 12/18639 0.416666666666667 2.92955488494908 0.01924115198476 0.130621634865613 GO:0005007 fibroblast growth factor receptor activity 13/2651 50/18639 0.26 1.82804224820822 0.0200613493763591 0.135340025019704 GO:0016769 transferase activity, transferring nitrogenous groups 9/2651 30/18639 0.3 2.10927951716333 0.0201417197447699 0.135340025019704 GO:0030295 protein kinase activator activity 29/2651 139/18639 0.20863309352518 1.46688503591695 0.0204186933270425 0.1365046655417 GO:0010314 phosphatidylinositol-5-phosphate binding 7/2651 21/18639 0.333333333333333 2.34364390795926 0.0219262499915156 0.145842784034475 GO:0005030 neurotrophin receptor activity 13/2651 51/18639 0.254901960784314 1.79219828255708 0.0235206916982872 0.155041223798481 GO:0016500 protein-hormone receptor activity 16/2651 67/18639 0.238805970149254 1.6790284713738 0.0235446049807868 0.155041223798481 GO:0030276 clathrin binding 12/2651 46/18639 0.260869565217391 1.83415610188116 0.0243077865505866 0.157611906588486 GO:0070325 lipoprotein particle receptor binding 9/2651 31/18639 0.290322580645161 2.04123824241613 0.0248960538218245 0.157611906588486 GO:0072349 modified amino acid transmembrane transporter activity 9/2651 31/18639 0.290322580645161 2.04123824241613 0.0248960538218245 0.157611906588486 GO:0022853 active monoatomic ion transmembrane transporter activity 25/2651 118/18639 0.211864406779661 1.48960417878767 0.0249674112893651 0.157611906588486 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 6/2651 17/18639 0.352941176470588 2.48150531430981 0.0250462868765783 0.157611906588486 GO:0019198 transmembrane receptor protein phosphatase activity 6/2651 17/18639 0.352941176470588 2.48150531430981 0.0250462868765783 0.157611906588486 GO:0051117 ATPase binding 19/2651 84/18639 0.226190476190476 1.59032979468664 0.0250784480013753 0.157611906588486 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 10/2651 36/18639 0.277777777777778 1.95303658996605 0.0251317390915582 0.157611906588486 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 10/2651 36/18639 0.277777777777778 1.95303658996605 0.0251317390915582 0.157611906588486 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 10/2651 36/18639 0.277777777777778 1.95303658996605 0.0251317390915582 0.157611906588486 GO:0140789 histone phosphatase activity 28/2651 136/18639 0.205882352941176 1.44754476668072 0.0263449505450184 0.164437440131703 GO:0005080 protein kinase C binding 13/2651 52/18639 0.25 1.75773293096945 0.0274024378645104 0.17009525214366 GO:0008201 heparin binding 34/2651 172/18639 0.197674418604651 1.38983534076654 0.0275097104833709 0.17009525214366 GO:0019104 DNA N-glycosylase activity 5/2651 13/18639 0.384615384615385 2.70420450918376 0.027673160087736 0.170306316988543 GO:0008093 cytoskeletal anchor activity 7/2651 22/18639 0.318181818181818 2.23711463941566 0.0283101032536219 0.173415841790791 GO:0072341 modified amino acid binding 20/2651 91/18639 0.21978021978022 1.54525971953358 0.0292918214625646 0.178598744750915 GO:0016859 cis-trans isomerase activity 11/2651 42/18639 0.261904761904762 1.84143449911085 0.0295104468740705 0.179102573885488 GO:0016874 ligase activity 33/2651 167/18639 0.197604790419162 1.3893457897483 0.0296660198201245 0.179220862858275 GO:0043425 bHLH transcription factor binding 9/2651 32/18639 0.28125 1.97744954734063 0.0303942468246046 0.18278184049317 GO:0005003 ephrin receptor activity 13/2651 53/18639 0.245283018867925 1.724568158687 0.0317325051419958 0.188250942666705 GO:0005005 transmembrane-ephrin receptor activity 13/2651 53/18639 0.245283018867925 1.724568158687 0.0317325051419958 0.188250942666705 GO:0038064 collagen receptor activity 13/2651 53/18639 0.245283018867925 1.724568158687 0.0317325051419958 0.188250942666705 GO:0005201 extracellular matrix structural constituent 33/2651 168/18639 0.196428571428571 1.38107587433314 0.0320399409107931 0.189222431298272 GO:0031690 adrenergic receptor binding 6/2651 18/18639 0.333333333333333 2.34364390795926 0.0331604769417998 0.194099325032668 GO:0070628 proteasome binding 6/2651 18/18639 0.333333333333333 2.34364390795926 0.0331604769417998 0.194099325032668 GO:0005539 glycosaminoglycan binding 45/2651 242/18639 0.18595041322314 1.30740465939876 0.0342973350875481 0.199865443850889 GO:0016757 glycosyltransferase activity 49/2651 267/18639 0.183520599250936 1.29032080325847 0.0348547211430323 0.202218800640412 GO:0000295 adenine nucleotide transmembrane transporter activity 7/2651 23/18639 0.304347826086957 2.13984878552802 0.035841272143023 0.206126442848739 GO:0003887 DNA-directed DNA polymerase activity 7/2651 23/18639 0.304347826086957 2.13984878552802 0.035841272143023 0.206126442848739 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 26/2651 128/18639 0.203125 1.42815800641267 0.0365264632093891 0.209153704551154 GO:0015291 secondary active transmembrane transporter activity 52/2651 287/18639 0.181184668989547 1.2738970370789 0.0376062917685996 0.214404702420977 GO:1901612 cardiolipin binding 5/2651 14/18639 0.357142857142857 2.51104704424207 0.0381225042739525 0.216410940210325 GO:0016763 pentosyltransferase activity 12/2651 49/18639 0.244897959183673 1.72186083033742 0.0385806153714199 0.218071546970644 GO:0035591 signaling adaptor activity 26/2651 129/18639 0.201550387596899 1.4170870141149 0.0397704909197296 0.223836480945657 GO:0001223 transcription coactivator binding 11/2651 44/18639 0.25 1.75773293096945 0.0405506663150314 0.227256287391048 GO:0008239 dipeptidyl-peptidase activity 4/2651 10/18639 0.4 2.81237268955111 0.0420315283543688 0.228206993749188 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 4/2651 10/18639 0.4 2.81237268955111 0.0420315283543688 0.228206993749188 GO:0015643 toxic substance binding 4/2651 10/18639 0.4 2.81237268955111 0.0420315283543688 0.228206993749188 GO:0016868 intramolecular phosphotransferase activity 4/2651 10/18639 0.4 2.81237268955111 0.0420315283543688 0.228206993749188 GO:0016889 DNA endonuclease activity, producing 3'-phosphomonoesters 4/2651 10/18639 0.4 2.81237268955111 0.0420315283543688 0.228206993749188 GO:0051880 G-quadruplex DNA binding 4/2651 10/18639 0.4 2.81237268955111 0.0420315283543688 0.228206993749188 GO:0097177 mitochondrial ribosome binding 4/2651 10/18639 0.4 2.81237268955111 0.0420315283543688 0.228206993749188 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 10/2651 39/18639 0.256410256410256 1.80280300612251 0.0423453555959484 0.228206993749188 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 10/2651 39/18639 0.256410256410256 1.80280300612251 0.0423453555959484 0.228206993749188 GO:0005520 insulin-like growth factor binding 6/2651 19/18639 0.315789473684211 2.22029422859298 0.0427996411966966 0.228206993749188 GO:0008301 DNA binding, bending 6/2651 19/18639 0.315789473684211 2.22029422859298 0.0427996411966966 0.228206993749188 GO:0046527 glucosyltransferase activity 6/2651 19/18639 0.315789473684211 2.22029422859298 0.0427996411966966 0.228206993749188 GO:0015399 primary active transmembrane transporter activity 32/2651 166/18639 0.192771084337349 1.35536033231379 0.0432011363047324 0.22941893755376 GO:0015605 organophosphate ester transmembrane transporter activity 12/2651 50/18639 0.24 1.68742361373067 0.0444288046330181 0.233001033175122 GO:0005315 phosphate transmembrane transporter activity 7/2651 24/18639 0.291666666666667 2.05068841946435 0.0445833411997956 0.233001033175122 GO:0050431 transforming growth factor beta binding 7/2651 24/18639 0.291666666666667 2.05068841946435 0.0445833411997956 0.233001033175122 GO:0140033 acetylation-dependent protein binding 7/2651 24/18639 0.291666666666667 2.05068841946435 0.0445833411997956 0.233001033175122 GO:0140662 ATP-dependent protein folding chaperone 10/2651 40/18639 0.25 1.75773293096945 0.0495259736245239 0.257809119618569 GO:0015556 C4-dicarboxylate transmembrane transporter activity 5/2651 15/18639 0.333333333333333 2.34364390795926 0.0506732746928612 0.260643371164939 GO:0050780 dopamine receptor binding 5/2651 15/18639 0.333333333333333 2.34364390795926 0.0506732746928612 0.260643371164939 GO:0019955 cytokine binding 28/2651 144/18639 0.194444444444444 1.36712561297624 0.0506956168428665 0.260643371164939 GO:0016597 amino acid binding 12/2651 51/18639 0.235294117647059 1.65433687620654 0.0508620701513966 0.260643371164939 GO:0140566 histone reader activity 9/2651 35/18639 0.257142857142857 1.80795387185429 0.0518009911015653 0.264346108625413 GO:0031406 carboxylic acid binding 35/2651 187/18639 0.18716577540107 1.31594978789156 0.0519860608458481 0.264346108625413 GO:0015215 nucleotide transmembrane transporter activity 8/2651 30/18639 0.266666666666667 1.87491512636741 0.0536163330023968 0.271558789862988 GO:0015932 nucleobase-containing compound transmembrane transporter activity 13/2651 57/18639 0.228070175438596 1.6035458317616 0.0540001160438489 0.271558789862988 GO:0043024 ribosomal small subunit binding 6/2651 20/18639 0.3 2.10927951716333 0.0540230849993189 0.271558789862988 GO:0017124 SH3 domain binding 23/2651 115/18639 0.2 1.40618634477556 0.0546800094664958 0.271749330065566 GO:0035401 histone H3Y41 kinase activity 23/2651 115/18639 0.2 1.40618634477556 0.0546800094664958 0.271749330065566 GO:0140801 histone H2AXY142 kinase activity 23/2651 115/18639 0.2 1.40618634477556 0.0546800094664958 0.271749330065566 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 10/2651 41/18639 0.24390243902439 1.71486139606775 0.0574756415740673 0.283347064161112 GO:0140297 DNA-binding transcription factor binding 82/2651 488/18639 0.168032786885246 1.18142705196307 0.0584829635312149 0.283347064161112 GO:0019206 nucleoside kinase activity 4/2651 11/18639 0.363636363636364 2.55670244504647 0.0587986422086948 0.283347064161112 GO:0034056 estrogen response element binding 4/2651 11/18639 0.363636363636364 2.55670244504647 0.0587986422086948 0.283347064161112 GO:0045294 alpha-catenin binding 4/2651 11/18639 0.363636363636364 2.55670244504647 0.0587986422086948 0.283347064161112 GO:0050998 nitric-oxide synthase binding 4/2651 11/18639 0.363636363636364 2.55670244504647 0.0587986422086948 0.283347064161112 GO:0097493 structural molecule activity conferring elasticity 4/2651 11/18639 0.363636363636364 2.55670244504647 0.0587986422086948 0.283347064161112 GO:0140031 phosphorylation-dependent protein binding 4/2651 11/18639 0.363636363636364 2.55670244504647 0.0587986422086948 0.283347064161112 GO:0043177 organic acid binding 35/2651 189/18639 0.185185185185185 1.3020243933107 0.0590947412125167 0.283347064161112 GO:0051087 protein-folding chaperone binding 26/2651 134/18639 0.194029850746269 1.36421063299121 0.0592571095507101 0.283347064161112 GO:0009055 electron transfer activity 23/2651 116/18639 0.198275862068966 1.39406404869991 0.0593802503481147 0.283347064161112 GO:0003725 double-stranded RNA binding 16/2651 75/18639 0.213333333333333 1.49993210109393 0.0602460997149745 0.286440842327153 GO:0019902 phosphatase binding 35/2651 190/18639 0.184210526315789 1.29517163334591 0.0629008672698836 0.297987202138262 GO:0005310 dicarboxylic acid transmembrane transporter activity 8/2651 31/18639 0.258064516129032 1.81443399325878 0.0636059953260742 0.300247655356415 GO:0005024 transforming growth factor beta receptor activity 5/2651 16/18639 0.3125 2.19716616371181 0.0653563968924662 0.306314500738 GO:0008296 3'-5'-DNA exonuclease activity 5/2651 16/18639 0.3125 2.19716616371181 0.0653563968924662 0.306314500738 GO:0015216 purine nucleotide transmembrane transporter activity 7/2651 26/18639 0.269230769230769 1.89294315642863 0.0658733212424141 0.307642425802338 GO:0008307 structural constituent of muscle 10/2651 42/18639 0.238095238095238 1.67403136282804 0.0662147649178162 0.308144330023901 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 13/2651 59/18639 0.220338983050847 1.54918834593917 0.0683694757956229 0.315938946045036 GO:0045309 protein phosphorylated amino acid binding 13/2651 59/18639 0.220338983050847 1.54918834593917 0.0683694757956229 0.315938946045036 GO:0042805 actinin binding 9/2651 37/18639 0.243243243243243 1.71022663553784 0.0704971769394375 0.323591491639278 GO:0140693 molecular condensate scaffold activity 11/2651 48/18639 0.229166666666667 1.61125518672199 0.0705169006078002 0.323591491639278 GO:0003925 G protein activity 12/2651 54/18639 0.222222222222222 1.56242927197284 0.0738510939930854 0.336546334909666 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 12/2651 54/18639 0.222222222222222 1.56242927197284 0.0738510939930854 0.336546334909666 GO:0030515 snoRNA binding 8/2651 32/18639 0.25 1.75773293096945 0.0746765781598975 0.339134667022707 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 13/2651 60/18639 0.216666666666667 1.52336854017352 0.076412293752166 0.34483099972397 GO:0008514 organic anion transmembrane transporter activity 47/2651 269/18639 0.174721189591078 1.22845275472958 0.0764545572660586 0.34483099972397 GO:0035255 ionotropic glutamate receptor binding 7/2651 27/18639 0.259259259259259 1.82283415063498 0.0784648467235506 0.347608064066842 GO:0005049 nuclear export signal receptor activity 4/2651 12/18639 0.333333333333333 2.34364390795926 0.0785773873206622 0.347608064066842 GO:0008179 adenylate cyclase binding 4/2651 12/18639 0.333333333333333 2.34364390795926 0.0785773873206622 0.347608064066842 GO:0045295 gamma-catenin binding 4/2651 12/18639 0.333333333333333 2.34364390795926 0.0785773873206622 0.347608064066842 GO:0097371 MDM2/MDM4 family protein binding 4/2651 12/18639 0.333333333333333 2.34364390795926 0.0785773873206622 0.347608064066842 GO:0016829 lyase activity 36/2651 200/18639 0.18 1.265567710298 0.0786539127501282 0.347608064066842 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 25/2651 132/18639 0.189393939393939 1.33161585679503 0.0798169938552536 0.351280998631807 GO:0000146 microfilament motor activity 9/2651 38/18639 0.236842105263158 1.66522067144474 0.0812318330115144 0.351280998631807 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 6/2651 22/18639 0.272727272727273 1.91752683378485 0.081318712408247 0.351280998631807 GO:0031683 G-protein beta/gamma-subunit complex binding 6/2651 22/18639 0.272727272727273 1.91752683378485 0.081318712408247 0.351280998631807 GO:0004527 exonuclease activity 17/2651 84/18639 0.202380952380952 1.42292665840384 0.0814808981097633 0.351280998631807 GO:0004550 nucleoside diphosphate kinase activity 5/2651 17/18639 0.294117647058824 2.06792109525817 0.0821522760657528 0.351280998631807 GO:0005092 GDP-dissociation inhibitor activity 5/2651 17/18639 0.294117647058824 2.06792109525817 0.0821522760657528 0.351280998631807 GO:0017110 nucleoside diphosphate phosphatase activity 5/2651 17/18639 0.294117647058824 2.06792109525817 0.0821522760657528 0.351280998631807 GO:0038191 neuropilin binding 5/2651 17/18639 0.294117647058824 2.06792109525817 0.0821522760657528 0.351280998631807 GO:0070403 NAD+ binding 5/2651 17/18639 0.294117647058824 2.06792109525817 0.0821522760657528 0.351280998631807 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 13/2651 61/18639 0.213114754098361 1.49839528541658 0.0850383339753519 0.362444938011451 GO:0004518 nuclease activity 37/2651 209/18639 0.177033492822967 1.24471040087788 0.0912932396128257 0.387849021193843 GO:0016866 intramolecular transferase activity 7/2651 28/18639 0.25 1.75773293096945 0.0923541447950337 0.389841053509806 GO:0051393 alpha-actinin binding 7/2651 28/18639 0.25 1.75773293096945 0.0923541447950337 0.389841053509806 GO:0015294 solute:monoatomic cation symporter activity 22/2651 116/18639 0.189655172413793 1.33345256832165 0.0944489931851548 0.39740998091006 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 14/2651 68/18639 0.205882352941176 1.44754476668072 0.0955371440417761 0.397857791368113 GO:0032934 sterol binding 14/2651 68/18639 0.205882352941176 1.44754476668072 0.0955371440417761 0.397857791368113 GO:0048306 calcium-dependent protein binding 16/2651 80/18639 0.2 1.40618634477556 0.0967699542170511 0.397857791368113 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 17/2651 86/18639 0.197674418604651 1.38983534076654 0.0968837651159691 0.397857791368113 GO:0050660 flavin adenine dinucleotide binding 17/2651 86/18639 0.197674418604651 1.38983534076654 0.0968837651159691 0.397857791368113 GO:0005158 insulin receptor binding 6/2651 23/18639 0.260869565217391 1.83415610188116 0.0973695736783259 0.397857791368113 GO:0017134 fibroblast growth factor binding 6/2651 23/18639 0.260869565217391 1.83415610188116 0.0973695736783259 0.397857791368113 GO:0070577 lysine-acetylated histone binding 6/2651 23/18639 0.260869565217391 1.83415610188116 0.0973695736783259 0.397857791368113 GO:0015297 antiporter activity 25/2651 135/18639 0.185185185185185 1.3020243933107 0.0979341546213049 0.397857791368113 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 5/2651 18/18639 0.277777777777778 1.95303658996605 0.100995275728812 0.397857791368113 GO:0008409 5'-3' exonuclease activity 5/2651 18/18639 0.277777777777778 1.95303658996605 0.100995275728812 0.397857791368113 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 5/2651 18/18639 0.277777777777778 1.95303658996605 0.100995275728812 0.397857791368113 GO:0030228 lipoprotein particle receptor activity 5/2651 18/18639 0.277777777777778 1.95303658996605 0.100995275728812 0.397857791368113 GO:0034185 apolipoprotein binding 5/2651 18/18639 0.277777777777778 1.95303658996605 0.100995275728812 0.397857791368113 GO:1901611 phosphatidylglycerol binding 5/2651 18/18639 0.277777777777778 1.95303658996605 0.100995275728812 0.397857791368113 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 4/2651 13/18639 0.307692307692308 2.16336360734701 0.101201488313074 0.397857791368113 GO:0019855 calcium channel inhibitor activity 4/2651 13/18639 0.307692307692308 2.16336360734701 0.101201488313074 0.397857791368113 GO:0035673 oligopeptide transmembrane transporter activity 4/2651 13/18639 0.307692307692308 2.16336360734701 0.101201488313074 0.397857791368113 GO:0052650 all-trans-retinol dehydrogenase (NADP+) activity 4/2651 13/18639 0.307692307692308 2.16336360734701 0.101201488313074 0.397857791368113 GO:0061459 L-arginine transmembrane transporter activity 4/2651 13/18639 0.307692307692308 2.16336360734701 0.101201488313074 0.397857791368113 GO:0070123 transforming growth factor beta receptor activity, type III 4/2651 13/18639 0.307692307692308 2.16336360734701 0.101201488313074 0.397857791368113 GO:0140852 histone ubiquitin ligase activity 4/2651 13/18639 0.307692307692308 2.16336360734701 0.101201488313074 0.397857791368113 GO:0004601 peroxidase activity 12/2651 57/18639 0.210526315789474 1.48019615239532 0.102600413896378 0.400963635316111 GO:0016504 peptidase activator activity 12/2651 57/18639 0.210526315789474 1.48019615239532 0.102600413896378 0.400963635316111 GO:0005507 copper ion binding 13/2651 63/18639 0.206349206349206 1.45082718111764 0.104054656076875 0.40348912269096 GO:1901682 sulfur compound transmembrane transporter activity 13/2651 63/18639 0.206349206349206 1.45082718111764 0.104054656076875 0.40348912269096 GO:0044325 transmembrane transporter binding 25/2651 136/18639 0.183823529411765 1.29245068453636 0.10452134323732 0.40348912269096 GO:0051213 dioxygenase activity 18/2651 93/18639 0.193548387096774 1.36082549494409 0.104778496553006 0.40348912269096 GO:0051219 phosphoprotein binding 18/2651 93/18639 0.193548387096774 1.36082549494409 0.104778496553006 0.40348912269096 GO:0044183 protein folding chaperone 15/2651 75/18639 0.2 1.40618634477556 0.105370154360921 0.403687117342666 GO:0015101 organic cation transmembrane transporter activity 16/2651 81/18639 0.197530864197531 1.38882601953141 0.10544295244182 0.403687117342666 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 7/2651 29/18639 0.241379310344828 1.69712145059119 0.107520082399399 0.408080543285326 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 7/2651 29/18639 0.241379310344828 1.69712145059119 0.107520082399399 0.408080543285326 GO:0097472 cyclin-dependent protein kinase activity 7/2651 29/18639 0.241379310344828 1.69712145059119 0.107520082399399 0.408080543285326 GO:0034061 DNA polymerase activity 8/2651 35/18639 0.228571428571429 1.60707010831492 0.114375687077624 0.43013887668304 GO:0140034 methylation-dependent protein binding 15/2651 76/18639 0.197368421052632 1.38768389287061 0.114890642751999 0.43013887668304 GO:0042625 ATPase-coupled ion transmembrane transporter activity 6/2651 24/18639 0.25 1.75773293096945 0.114964984504503 0.43013887668304 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 6/2651 24/18639 0.25 1.75773293096945 0.114964984504503 0.43013887668304 GO:0046961 proton-transporting ATPase activity, rotational mechanism 6/2651 24/18639 0.25 1.75773293096945 0.114964984504503 0.43013887668304 GO:0008137 NADH dehydrogenase (ubiquinone) activity 9/2651 41/18639 0.219512195121951 1.54337525646098 0.118993512863637 0.44395030153374 GO:0003756 protein disulfide isomerase activity 5/2651 19/18639 0.263157894736842 1.85024519049415 0.121779430918853 0.450200879735938 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 5/2651 19/18639 0.263157894736842 1.85024519049415 0.121779430918853 0.450200879735938 GO:0050145 nucleoside monophosphate kinase activity 5/2651 19/18639 0.263157894736842 1.85024519049415 0.121779430918853 0.450200879735938 GO:0001784 phosphotyrosine residue binding 10/2651 47/18639 0.212765957446809 1.495942919974 0.122036229358944 0.450200879735938 GO:0001968 fibronectin binding 7/2651 30/18639 0.233333333333333 1.64055073557148 0.123925571346312 0.453407419014747 GO:0008106 alcohol dehydrogenase (NADP+) activity 7/2651 30/18639 0.233333333333333 1.64055073557148 0.123925571346312 0.453407419014747 GO:0016860 intramolecular oxidoreductase activity 11/2651 53/18639 0.207547169811321 1.45924998042746 0.123938246655512 0.453407419014747 GO:0070063 RNA polymerase binding 12/2651 59/18639 0.203389830508475 1.43002001163616 0.124995302863669 0.45600779465776 GO:0005347 ATP transmembrane transporter activity 4/2651 14/18639 0.285714285714286 2.00883763539365 0.126433081928722 0.457451562912438 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 4/2651 14/18639 0.285714285714286 2.00883763539365 0.126433081928722 0.457451562912438 GO:0042043 neurexin family protein binding 4/2651 14/18639 0.285714285714286 2.00883763539365 0.126433081928722 0.457451562912438 GO:0042826 histone deacetylase binding 23/2651 127/18639 0.181102362204724 1.2733183436944 0.130302897885215 0.47016141510912 GO:0015293 symporter activity 26/2651 146/18639 0.178082191780822 1.25208373164947 0.131207289241874 0.472131147353955 GO:0015662 P-type ion transporter activity 6/2651 25/18639 0.24 1.68742361373067 0.134032711610422 0.478376913796548 GO:0017056 structural constituent of nuclear pore 6/2651 25/18639 0.24 1.68742361373067 0.134032711610422 0.478376913796548 GO:0140358 P-type transmembrane transporter activity 6/2651 25/18639 0.24 1.68742361373067 0.134032711610422 0.478376913796548 GO:0001221 transcription coregulator binding 21/2651 115/18639 0.182608695652174 1.28390927131681 0.134643096929557 0.47925664501683 GO:0015485 cholesterol binding 11/2651 54/18639 0.203703703703704 1.43222683264177 0.136751239197063 0.484221902470277 GO:1901981 phosphatidylinositol phosphate binding 32/2651 185/18639 0.172972972972973 1.21616116304913 0.13703144669562 0.484221902470277 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 12/2651 60/18639 0.2 1.40618634477556 0.137141055141544 0.484221902470277 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 22/2651 122/18639 0.180327868852459 1.26787293381403 0.141038103359418 0.496650219583832 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 5/2651 20/18639 0.25 1.75773293096945 0.144364879558697 0.504319751667916 GO:0015095 magnesium ion transmembrane transporter activity 5/2651 20/18639 0.25 1.75773293096945 0.144364879558697 0.504319751667916 GO:0031418 L-ascorbic acid binding 5/2651 20/18639 0.25 1.75773293096945 0.144364879558697 0.504319751667916 GO:0016835 carbon-oxygen lyase activity 15/2651 79/18639 0.189873417721519 1.33498703617933 0.146383674406147 0.508673612646163 GO:0046332 SMAD binding 15/2651 79/18639 0.189873417721519 1.33498703617933 0.146383674406147 0.508673612646163 GO:0035091 phosphatidylinositol binding 47/2651 284/18639 0.165492957746479 1.16356968669808 0.148152650381861 0.513465896191872 GO:0140313 molecular sequestering activity 11/2651 55/18639 0.2 1.40618634477556 0.150242533456914 0.517686657316351 GO:0042626 ATPase-coupled transmembrane transporter activity 18/2651 98/18639 0.183673469387755 1.29139562275306 0.150926631001801 0.517686657316351 GO:0019208 phosphatase regulator activity 21/2651 117/18639 0.179487179487179 1.26196210428576 0.152739800124224 0.517686657316351 GO:1990782 protein tyrosine kinase binding 21/2651 117/18639 0.179487179487179 1.26196210428576 0.152739800124224 0.517686657316351 GO:0000774 adenyl-nucleotide exchange factor activity 4/2651 15/18639 0.266666666666667 1.87491512636741 0.153982102741763 0.517686657316351 GO:0004467 long-chain fatty acid-CoA ligase activity 4/2651 15/18639 0.266666666666667 1.87491512636741 0.153982102741763 0.517686657316351 GO:0004698 calcium,diacylglycerol-dependent serine/threonine kinase activity 4/2651 15/18639 0.266666666666667 1.87491512636741 0.153982102741763 0.517686657316351 GO:0004699 diacylglycerol-dependent, calcium-independent serine/threonine kinase activity 4/2651 15/18639 0.266666666666667 1.87491512636741 0.153982102741763 0.517686657316351 GO:0005041 low-density lipoprotein particle receptor activity 4/2651 15/18639 0.266666666666667 1.87491512636741 0.153982102741763 0.517686657316351 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 4/2651 15/18639 0.266666666666667 1.87491512636741 0.153982102741763 0.517686657316351 GO:0051371 muscle alpha-actinin binding 4/2651 15/18639 0.266666666666667 1.87491512636741 0.153982102741763 0.517686657316351 GO:0005160 transforming growth factor beta receptor binding 6/2651 26/18639 0.230769230769231 1.62252270551026 0.154480528720825 0.517686657316351 GO:0043548 phosphatidylinositol 3-kinase binding 6/2651 26/18639 0.230769230769231 1.62252270551026 0.154480528720825 0.517686657316351 GO:0035064 methylated histone binding 14/2651 74/18639 0.189189189189189 1.33017627208499 0.159881792009814 0.518498686309941 GO:0048029 monosaccharide binding 14/2651 74/18639 0.189189189189189 1.33017627208499 0.159881792009814 0.518498686309941 GO:0001094 TFIID-class transcription factor complex binding 3/2651 10/18639 0.3 2.10927951716333 0.159990200556876 0.518498686309941 GO:0005131 growth hormone receptor binding 3/2651 10/18639 0.3 2.10927951716333 0.159990200556876 0.518498686309941 GO:0005337 nucleoside transmembrane transporter activity 3/2651 10/18639 0.3 2.10927951716333 0.159990200556876 0.518498686309941 GO:0005522 profilin binding 3/2651 10/18639 0.3 2.10927951716333 0.159990200556876 0.518498686309941 GO:0008641 ubiquitin-like modifier activating enzyme activity 3/2651 10/18639 0.3 2.10927951716333 0.159990200556876 0.518498686309941 GO:0031419 cobalamin binding 3/2651 10/18639 0.3 2.10927951716333 0.159990200556876 0.518498686309941 GO:0031957 very long-chain fatty acid-CoA ligase activity 3/2651 10/18639 0.3 2.10927951716333 0.159990200556876 0.518498686309941 GO:0047429 nucleoside triphosphate diphosphatase activity 3/2651 10/18639 0.3 2.10927951716333 0.159990200556876 0.518498686309941 GO:0070097 delta-catenin binding 3/2651 10/18639 0.3 2.10927951716333 0.159990200556876 0.518498686309941 GO:0140135 mechanosensitive monoatomic cation channel activity 3/2651 10/18639 0.3 2.10927951716333 0.159990200556876 0.518498686309941 GO:0042910 xenobiotic transmembrane transporter activity 7/2651 32/18639 0.21875 1.53801631459826 0.160234597819397 0.518498686309941 GO:0051059 NF-kappaB binding 7/2651 32/18639 0.21875 1.53801631459826 0.160234597819397 0.518498686309941 GO:0005109 frizzled binding 8/2651 38/18639 0.210526315789474 1.48019615239532 0.163334825793233 0.524006408213628 GO:0042162 telomeric DNA binding 8/2651 38/18639 0.210526315789474 1.48019615239532 0.163334825793233 0.524006408213628 GO:0043531 ADP binding 8/2651 38/18639 0.210526315789474 1.48019615239532 0.163334825793233 0.524006408213628 GO:0030170 pyridoxal phosphate binding 11/2651 56/18639 0.196428571428571 1.38107587433314 0.164389452864708 0.524006408213628 GO:0003954 NADH dehydrogenase activity 9/2651 44/18639 0.204545454545455 1.43814512533864 0.164721832194717 0.524006408213628 GO:0016790 thiolester hydrolase activity 9/2651 44/18639 0.204545454545455 1.43814512533864 0.164721832194717 0.524006408213628 GO:0030020 extracellular matrix structural constituent conferring tensile strength 9/2651 44/18639 0.204545454545455 1.43814512533864 0.164721832194717 0.524006408213628 GO:0019903 protein phosphatase binding 25/2651 144/18639 0.173611111111111 1.22064786872878 0.167109918592761 0.529894748780404 GO:0015174 basic amino acid transmembrane transporter activity 5/2651 21/18639 0.238095238095238 1.67403136282804 0.168584585982528 0.529894748780404 GO:0061891 calcium ion sensor activity 5/2651 21/18639 0.238095238095238 1.67403136282804 0.168584585982528 0.529894748780404 GO:0072542 protein phosphatase activator activity 5/2651 21/18639 0.238095238095238 1.67403136282804 0.168584585982528 0.529894748780404 GO:1904047 S-adenosyl-L-methionine binding 5/2651 21/18639 0.238095238095238 1.67403136282804 0.168584585982528 0.529894748780404 GO:0005044 scavenger receptor activity 6/2651 27/18639 0.222222222222222 1.56242927197284 0.17619929500576 0.552510646482347 GO:0016758 hexosyltransferase activity 33/2651 197/18639 0.16751269035533 1.17777028877141 0.177958160945309 0.555164122876296 GO:0004197 cysteine-type endopeptidase activity 16/2651 88/18639 0.181818181818182 1.27835122252323 0.178763322976707 0.555164122876296 GO:0070279 vitamin B6 binding 11/2651 57/18639 0.192982456140351 1.35684647302905 0.179165092618005 0.555164122876296 GO:0019888 protein phosphatase regulator activity 19/2651 107/18639 0.177570093457944 1.2484832033054 0.179455710146475 0.555164122876296 GO:0019956 chemokine binding 7/2651 33/18639 0.212121212121212 1.49140975961044 0.17999626459239 0.555164122876296 GO:0140311 protein sequestering activity 7/2651 33/18639 0.212121212121212 1.49140975961044 0.17999626459239 0.555164122876296 GO:0140416 transcription regulator inhibitor activity 7/2651 33/18639 0.212121212121212 1.49140975961044 0.17999626459239 0.555164122876296 GO:0140303 intramembrane lipid transporter activity 9/2651 45/18639 0.2 1.40618634477556 0.181581878513164 0.556915009628438 GO:0004697 diacylglycerol-dependent serine/threonine kinase activity 4/2651 16/18639 0.25 1.75773293096945 0.183524004691528 0.556915009628438 GO:0005149 interleukin-1 receptor binding 4/2651 16/18639 0.25 1.75773293096945 0.183524004691528 0.556915009628438 GO:0005324 long-chain fatty acid transmembrane transporter activity 4/2651 16/18639 0.25 1.75773293096945 0.183524004691528 0.556915009628438 GO:0015562 efflux transmembrane transporter activity 4/2651 16/18639 0.25 1.75773293096945 0.183524004691528 0.556915009628438 GO:0034450 ubiquitin-ubiquitin ligase activity 4/2651 16/18639 0.25 1.75773293096945 0.183524004691528 0.556915009628438 GO:0140327 flippase activity 4/2651 16/18639 0.25 1.75773293096945 0.183524004691528 0.556915009628438 GO:0005543 phospholipid binding 78/2651 497/18639 0.156941649899396 1.10344602507539 0.186714473534243 0.565294164700226 GO:0004519 endonuclease activity 22/2651 127/18639 0.173228346456693 1.21795667657725 0.188404835016786 0.567936982598287 GO:0001216 DNA-binding transcription activator activity 77/2651 491/18639 0.156822810590631 1.10261047400935 0.190381166066658 0.567936982598287 GO:0005496 steroid binding 19/2651 108/18639 0.175925925925926 1.23692317364517 0.190463533234083 0.567936982598287 GO:0015377 chloride:monoatomic cation symporter activity 5/2651 22/18639 0.227272727272727 1.59793902815404 0.194251019386728 0.567936982598287 GO:0034062 5'-3' RNA polymerase activity 5/2651 22/18639 0.227272727272727 1.59793902815404 0.194251019386728 0.567936982598287 GO:0061133 endopeptidase activator activity 5/2651 22/18639 0.227272727272727 1.59793902815404 0.194251019386728 0.567936982598287 GO:0097747 RNA polymerase activity 5/2651 22/18639 0.227272727272727 1.59793902815404 0.194251019386728 0.567936982598287 GO:0140784 metal ion sensor activity 5/2651 22/18639 0.227272727272727 1.59793902815404 0.194251019386728 0.567936982598287 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 11/2651 58/18639 0.189655172413793 1.33345256832165 0.194538624072583 0.567936982598287 GO:0001540 amyloid-beta binding 15/2651 83/18639 0.180722891566265 1.27065031154418 0.194867320559185 0.567936982598287 GO:0030159 signaling receptor complex adaptor activity 10/2651 52/18639 0.192307692307692 1.35210225459188 0.197096055755998 0.567936982598287 GO:0004016 adenylate cyclase activity 3/2651 11/18639 0.272727272727273 1.91752683378485 0.197937034937444 0.567936982598287 GO:0004143 ATP-dependent diacylglycerol kinase activity 3/2651 11/18639 0.272727272727273 1.91752683378485 0.197937034937444 0.567936982598287 GO:0004523 RNA-DNA hybrid ribonuclease activity 3/2651 11/18639 0.272727272727273 1.91752683378485 0.197937034937444 0.567936982598287 GO:0005536 D-glucose binding 3/2651 11/18639 0.272727272727273 1.91752683378485 0.197937034937444 0.567936982598287 GO:0010854 adenylate cyclase regulator activity 3/2651 11/18639 0.272727272727273 1.91752683378485 0.197937034937444 0.567936982598287 GO:0015217 ADP transmembrane transporter activity 3/2651 11/18639 0.272727272727273 1.91752683378485 0.197937034937444 0.567936982598287 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 3/2651 11/18639 0.272727272727273 1.91752683378485 0.197937034937444 0.567936982598287 GO:0032794 GTPase activating protein binding 3/2651 11/18639 0.272727272727273 1.91752683378485 0.197937034937444 0.567936982598287 GO:0035252 UDP-xylosyltransferase activity 3/2651 11/18639 0.272727272727273 1.91752683378485 0.197937034937444 0.567936982598287 GO:0042285 xylosyltransferase activity 3/2651 11/18639 0.272727272727273 1.91752683378485 0.197937034937444 0.567936982598287 GO:0047676 arachidonate-CoA ligase activity 3/2651 11/18639 0.272727272727273 1.91752683378485 0.197937034937444 0.567936982598287 GO:0048185 activin binding 3/2651 11/18639 0.272727272727273 1.91752683378485 0.197937034937444 0.567936982598287 GO:0050786 RAGE receptor binding 3/2651 11/18639 0.272727272727273 1.91752683378485 0.197937034937444 0.567936982598287 GO:0016407 acetyltransferase activity 17/2651 96/18639 0.177083333333333 1.24506082610336 0.199059132002832 0.568482730076478 GO:0030291 protein serine/threonine kinase inhibitor activity 9/2651 46/18639 0.195652173913043 1.37561707641087 0.199173742859457 0.568482730076478 GO:0008376 acetylgalactosaminyltransferase activity 7/2651 34/18639 0.205882352941176 1.44754476668072 0.200717137042948 0.568482730076478 GO:0015035 protein-disulfide reductase activity 7/2651 34/18639 0.205882352941176 1.44754476668072 0.200717137042948 0.568482730076478 GO:0016831 carboxy-lyase activity 7/2651 34/18639 0.205882352941176 1.44754476668072 0.200717137042948 0.568482730076478 GO:0030332 cyclin binding 7/2651 34/18639 0.205882352941176 1.44754476668072 0.200717137042948 0.568482730076478 GO:0016791 phosphatase activity 44/2651 273/18639 0.161172161172161 1.13319046099129 0.205420636733481 0.580555748021447 GO:0034212 protein N-acetyltransferase activity 10/2651 53/18639 0.188679245283019 1.32659089129769 0.214109499732856 0.599599011258879 GO:0004029 aldehyde dehydrogenase (NAD+) activity 4/2651 17/18639 0.235294117647059 1.65433687620654 0.214715305807151 0.599599011258879 GO:0004659 prenyltransferase activity 4/2651 17/18639 0.235294117647059 1.65433687620654 0.214715305807151 0.599599011258879 GO:0015278 intracellularly gated calcium channel activity 4/2651 17/18639 0.235294117647059 1.65433687620654 0.214715305807151 0.599599011258879 GO:0016018 cyclosporin A binding 4/2651 17/18639 0.235294117647059 1.65433687620654 0.214715305807151 0.599599011258879 GO:0016779 nucleotidyltransferase activity 23/2651 136/18639 0.169117647058824 1.18905462977345 0.214890458097336 0.599599011258879 GO:0061733 protein-lysine-acetyltransferase activity 9/2651 47/18639 0.191489361702128 1.3463486279766 0.217443153951684 0.605438971996549 GO:0016877 ligase activity, forming carbon-sulfur bonds 8/2651 41/18639 0.195121951219512 1.3718891168542 0.220281218394168 0.610631142041882 GO:0042169 SH2 domain binding 8/2651 41/18639 0.195121951219512 1.3718891168542 0.220281218394168 0.610631142041882 GO:0004602 glutathione peroxidase activity 5/2651 23/18639 0.217391304347826 1.5284634182343 0.221162532083506 0.610631142041882 GO:0140103 catalytic activity, acting on a glycoprotein 5/2651 23/18639 0.217391304347826 1.5284634182343 0.221162532083506 0.610631142041882 GO:0010485 histone H4 acetyltransferase activity 7/2651 35/18639 0.2 1.40618634477556 0.222302499534279 0.612494543695911 GO:0016417 S-acyltransferase activity 6/2651 29/18639 0.206896551724138 1.45467552907816 0.222947738090159 0.612989918715531 GO:1902936 phosphatidylinositol bisphosphate binding 19/2651 111/18639 0.171171171171171 1.2034928176007 0.225390953026111 0.618416427365393 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 11/2651 60/18639 0.183333333333333 1.28900414937759 0.226938500090217 0.62136799297051 GO:0016209 antioxidant activity 15/2651 86/18639 0.174418604651163 1.22632530067636 0.235573148505553 0.624914092447866 GO:0004300 enoyl-CoA hydratase activity 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.624914092447866 GO:0005025 transforming growth factor beta receptor activity, type I 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.624914092447866 GO:0005026 transforming growth factor beta receptor activity, type II 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.624914092447866 GO:0005095 GTPase inhibitor activity 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.624914092447866 GO:0005165 neurotrophin receptor binding 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.624914092447866 GO:0016361 activin receptor activity, type I 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.624914092447866 GO:0016362 activin receptor activity, type II 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.624914092447866 GO:0016423 tRNA (guanine) methyltransferase activity 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.624914092447866 GO:0016801 hydrolase activity, acting on ether bonds 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.624914092447866 GO:0016803 ether hydrolase activity 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.624914092447866 GO:0017002 activin receptor activity 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.624914092447866 GO:0017166 vinculin binding 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.624914092447866 GO:0042301 phosphate ion binding 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.624914092447866 GO:0043047 single-stranded telomeric DNA binding 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.624914092447866 GO:0070008 serine-type exopeptidase activity 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.624914092447866 GO:0140807 NAD+-protein-glutamate ADP-ribosyltransferase activity 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.624914092447866 GO:0140822 NAD+-histone H2BE35 glutamate ADP-ribosyltransferase activity 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.624914092447866 GO:0140844 NAD+-histone H2BE2 glutamate ADP-ribosyltransferase activity 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.624914092447866 GO:0140867 NAD+-histone H2BE18 glutamate ADP-ribosyltransferase activity 3/2651 12/18639 0.25 1.75773293096945 0.237723584143038 0.624914092447866 GO:0004402 histone acetyltransferase activity 8/2651 42/18639 0.19047619047619 1.33922509026243 0.240726748169534 0.631548062428838 GO:0015103 inorganic anion transmembrane transporter activity 27/2651 165/18639 0.163636363636364 1.15051610027091 0.244155279604037 0.636770512662836 GO:0004033 aldo-keto reductase (NADPH) activity 7/2651 36/18639 0.194444444444444 1.36712561297624 0.244651389071674 0.636770512662836 GO:0016409 palmitoyltransferase activity 7/2651 36/18639 0.194444444444444 1.36712561297624 0.244651389071674 0.636770512662836 GO:0044390 ubiquitin-like protein conjugating enzyme binding 7/2651 36/18639 0.194444444444444 1.36712561297624 0.244651389071674 0.636770512662836 GO:0015078 proton transmembrane transporter activity 30/2651 185/18639 0.162162162162162 1.14015109035856 0.245785742262564 0.638375059793411 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 4/2651 18/18639 0.222222222222222 1.56242927197284 0.247206742972391 0.638375059793411 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 4/2651 18/18639 0.222222222222222 1.56242927197284 0.247206742972391 0.638375059793411 GO:0017128 phospholipid scramblase activity 4/2651 18/18639 0.222222222222222 1.56242927197284 0.247206742972391 0.638375059793411 GO:0005540 hyaluronic acid binding 5/2651 24/18639 0.208333333333333 1.46477744247454 0.249109255130613 0.639526099428883 GO:0015295 solute:proton symporter activity 5/2651 24/18639 0.208333333333333 1.46477744247454 0.249109255130613 0.639526099428883 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 5/2651 24/18639 0.208333333333333 1.46477744247454 0.249109255130613 0.639526099428883 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 8/2651 43/18639 0.186046511627907 1.30808032072145 0.261774528910699 0.670733569212821 GO:0005516 calmodulin binding 33/2651 207/18639 0.159420289855072 1.12087317337182 0.265471781600845 0.677854672602791 GO:0008234 cysteine-type peptidase activity 30/2651 187/18639 0.160427807486631 1.12795696104991 0.265583151908155 0.677854672602791 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 74/2651 484/18639 0.152892561983471 1.07497716439454 0.2663576006812 0.678516363824256 GO:0008080 N-acetyltransferase activity 12/2651 69/18639 0.173913043478261 1.22277073458744 0.27122402853699 0.682196729328624 GO:0008276 protein methyltransferase activity 16/2651 95/18639 0.168421052631579 1.18415692191626 0.271521496353869 0.682196729328624 GO:0008327 methyl-CpG binding 6/2651 31/18639 0.193548387096774 1.36082549494409 0.273187559477858 0.682196729328624 GO:0070273 phosphatidylinositol-4-phosphate binding 6/2651 31/18639 0.193548387096774 1.36082549494409 0.273187559477858 0.682196729328624 GO:0046943 carboxylic acid transmembrane transporter activity 30/2651 188/18639 0.159574468085106 1.1219571899805 0.275716533710087 0.682196729328624 GO:0015296 monoatomic anion:monoatomic cation symporter activity 5/2651 25/18639 0.2 1.40618634477556 0.27787839101066 0.682196729328624 GO:0015645 fatty acid ligase activity 5/2651 25/18639 0.2 1.40618634477556 0.27787839101066 0.682196729328624 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 5/2651 25/18639 0.2 1.40618634477556 0.27787839101066 0.682196729328624 GO:0019211 phosphatase activator activity 5/2651 25/18639 0.2 1.40618634477556 0.27787839101066 0.682196729328624 GO:0019706 protein-cysteine S-palmitoyltransferase activity 5/2651 25/18639 0.2 1.40618634477556 0.27787839101066 0.682196729328624 GO:0019707 protein-cysteine S-acyltransferase activity 5/2651 25/18639 0.2 1.40618634477556 0.27787839101066 0.682196729328624 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 5/2651 25/18639 0.2 1.40618634477556 0.27787839101066 0.682196729328624 GO:0120515 fatty acid-CoA ligase activity 5/2651 25/18639 0.2 1.40618634477556 0.27787839101066 0.682196729328624 GO:0016741 transferase activity, transferring one-carbon groups 34/2651 215/18639 0.158139534883721 1.11186827261323 0.277976609024088 0.682196729328624 GO:0035325 Toll-like receptor binding 3/2651 13/18639 0.230769230769231 1.62252270551026 0.278680212892027 0.682196729328624 GO:0043560 insulin receptor substrate binding 3/2651 13/18639 0.230769230769231 1.62252270551026 0.278680212892027 0.682196729328624 GO:0051011 microtubule minus-end binding 3/2651 13/18639 0.230769230769231 1.62252270551026 0.278680212892027 0.682196729328624 GO:0070700 BMP receptor binding 3/2651 13/18639 0.230769230769231 1.62252270551026 0.278680212892027 0.682196729328624 GO:0071837 HMG box domain binding 3/2651 13/18639 0.230769230769231 1.62252270551026 0.278680212892027 0.682196729328624 GO:0097157 pre-mRNA intronic binding 3/2651 13/18639 0.230769230769231 1.62252270551026 0.278680212892027 0.682196729328624 GO:0140806 NAD+-protein-aspartate ADP-ribosyltransferase activity 3/2651 13/18639 0.230769230769231 1.62252270551026 0.278680212892027 0.682196729328624 GO:0015245 fatty acid transmembrane transporter activity 4/2651 19/18639 0.210526315789474 1.48019615239532 0.280654026186668 0.683218766151279 GO:0046624 sphingolipid transporter activity 4/2651 19/18639 0.210526315789474 1.48019615239532 0.280654026186668 0.683218766151279 GO:0140036 ubiquitin-modified protein reader activity 4/2651 19/18639 0.210526315789474 1.48019615239532 0.280654026186668 0.683218766151279 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 36/2651 229/18639 0.157205240174672 1.10529931030393 0.283377185596972 0.688575190832494 GO:0005525 GTP binding 58/2651 378/18639 0.153439153439153 1.07882021160029 0.285111243622488 0.691512905802609 GO:0005342 organic acid transmembrane transporter activity 30/2651 189/18639 0.158730158730159 1.11602090855203 0.285996131849446 0.692384017731103 GO:0019210 kinase inhibitor activity 15/2651 90/18639 0.166666666666667 1.17182195397963 0.294548894863381 0.71178145786252 GO:0016830 carbon-carbon lyase activity 9/2651 51/18639 0.176470588235294 1.2407526571549 0.296072952465275 0.71415398973767 GO:0140142 nucleocytoplasmic carrier activity 6/2651 32/18639 0.1875 1.31829969822708 0.299253627552888 0.720506448788214 GO:0043021 ribonucleoprotein complex binding 28/2651 177/18639 0.15819209039548 1.11223778682812 0.300986506470938 0.723356257339826 GO:0004860 protein kinase inhibitor activity 14/2651 84/18639 0.166666666666667 1.17182195397963 0.303578289250238 0.728256114649477 GO:0004715 non-membrane spanning protein tyrosine kinase activity 8/2651 45/18639 0.177777777777778 1.24994341757827 0.30534393891989 0.729116909769232 GO:0046915 transition metal ion transmembrane transporter activity 8/2651 45/18639 0.177777777777778 1.24994341757827 0.30534393891989 0.729116909769232 GO:0008408 3'-5' exonuclease activity 10/2651 58/18639 0.172413793103448 1.21222960756513 0.306664941165314 0.729116909769232 GO:0005112 Notch binding 5/2651 26/18639 0.192307692307692 1.35210225459188 0.307258834413002 0.729116909769232 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 5/2651 26/18639 0.192307692307692 1.35210225459188 0.307258834413002 0.729116909769232 GO:0070006 metalloaminopeptidase activity 5/2651 26/18639 0.192307692307692 1.35210225459188 0.307258834413002 0.729116909769232 GO:0000339 RNA cap binding 4/2651 20/18639 0.2 1.40618634477556 0.31472631284366 0.74374998534597 GO:0005326 neurotransmitter transmembrane transporter activity 4/2651 20/18639 0.2 1.40618634477556 0.31472631284366 0.74374998534597 GO:0004705 JUN kinase activity 3/2651 14/18639 0.214285714285714 1.50662822654524 0.320202157700201 0.74374998534597 GO:0005161 platelet-derived growth factor receptor binding 3/2651 14/18639 0.214285714285714 1.50662822654524 0.320202157700201 0.74374998534597 GO:0005545 1-phosphatidylinositol binding 3/2651 14/18639 0.214285714285714 1.50662822654524 0.320202157700201 0.74374998534597 GO:0008474 palmitoyl-(protein) hydrolase activity 3/2651 14/18639 0.214285714285714 1.50662822654524 0.320202157700201 0.74374998534597 GO:0016530 metallochaperone activity 3/2651 14/18639 0.214285714285714 1.50662822654524 0.320202157700201 0.74374998534597 GO:0098599 palmitoyl hydrolase activity 3/2651 14/18639 0.214285714285714 1.50662822654524 0.320202157700201 0.74374998534597 GO:0098821 BMP receptor activity 3/2651 14/18639 0.214285714285714 1.50662822654524 0.320202157700201 0.74374998534597 GO:0098847 sequence-specific single stranded DNA binding 3/2651 14/18639 0.214285714285714 1.50662822654524 0.320202157700201 0.74374998534597 GO:1901474 azole transmembrane transporter activity 3/2651 14/18639 0.214285714285714 1.50662822654524 0.320202157700201 0.74374998534597 GO:1990825 sequence-specific mRNA binding 3/2651 14/18639 0.214285714285714 1.50662822654524 0.320202157700201 0.74374998534597 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 6/2651 33/18639 0.181818181818182 1.27835122252323 0.325755263766332 0.753988896977607 GO:0030296 protein tyrosine kinase activator activity 6/2651 33/18639 0.181818181818182 1.27835122252323 0.325755263766332 0.753988896977607 GO:0042578 phosphoric ester hydrolase activity 55/2651 363/18639 0.151515151515152 1.06529268543603 0.32647572610959 0.754330756642684 GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 8/2651 46/18639 0.173913043478261 1.22277073458744 0.327695559143139 0.755823207340656 GO:0004364 glutathione transferase activity 5/2651 27/18639 0.185185185185185 1.3020243933107 0.337045093369193 0.77332471771294 GO:0016405 CoA-ligase activity 5/2651 27/18639 0.185185185185185 1.3020243933107 0.337045093369193 0.77332471771294 GO:0140326 ATPase-coupled intramembrane lipid transporter activity 5/2651 27/18639 0.185185185185185 1.3020243933107 0.337045093369193 0.77332471771294 GO:0004177 aminopeptidase activity 7/2651 40/18639 0.175 1.23041305167861 0.339542156495317 0.773662664540367 GO:0015036 disulfide oxidoreductase activity 7/2651 40/18639 0.175 1.23041305167861 0.339542156495317 0.773662664540367 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 7/2651 40/18639 0.175 1.23041305167861 0.339542156495317 0.773662664540367 GO:0071949 FAD binding 7/2651 40/18639 0.175 1.23041305167861 0.339542156495317 0.773662664540367 GO:0001098 basal transcription machinery binding 10/2651 60/18639 0.166666666666667 1.17182195397963 0.346166794110706 0.784609720473918 GO:0001099 basal RNA polymerase II transcription machinery binding 10/2651 60/18639 0.166666666666667 1.17182195397963 0.346166794110706 0.784609720473918 GO:0019001 guanyl nucleotide binding 60/2651 400/18639 0.15 1.05463975858167 0.347695491081607 0.784609720473918 GO:0032561 guanyl ribonucleotide binding 60/2651 400/18639 0.15 1.05463975858167 0.347695491081607 0.784609720473918 GO:0001846 opsonin binding 4/2651 21/18639 0.19047619047619 1.33922509026243 0.349112601516869 0.784609720473918 GO:0005123 death receptor binding 4/2651 21/18639 0.19047619047619 1.33922509026243 0.349112601516869 0.784609720473918 GO:0009931 calcium-dependent protein serine/threonine kinase activity 4/2651 21/18639 0.19047619047619 1.33922509026243 0.349112601516869 0.784609720473918 GO:0051010 microtubule plus-end binding 4/2651 21/18639 0.19047619047619 1.33922509026243 0.349112601516869 0.784609720473918 GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters 6/2651 34/18639 0.176470588235294 1.2407526571549 0.3525491480642 0.790983352641484 GO:0042562 hormone binding 15/2651 94/18639 0.159574468085106 1.1219571899805 0.357376752932458 0.800450992537495 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 9/2651 54/18639 0.166666666666667 1.17182195397963 0.359011833666754 0.800729739136524 GO:0004129 cytochrome-c oxidase activity 3/2651 15/18639 0.2 1.40618634477556 0.361757171439812 0.800729739136524 GO:0004953 icosanoid receptor activity 3/2651 15/18639 0.2 1.40618634477556 0.361757171439812 0.800729739136524 GO:0005523 tropomyosin binding 3/2651 15/18639 0.2 1.40618634477556 0.361757171439812 0.800729739136524 GO:0015116 sulfate transmembrane transporter activity 3/2651 15/18639 0.2 1.40618634477556 0.361757171439812 0.800729739136524 GO:0033130 acetylcholine receptor binding 3/2651 15/18639 0.2 1.40618634477556 0.361757171439812 0.800729739136524 GO:0061578 K63-linked deubiquitinase activity 3/2651 15/18639 0.2 1.40618634477556 0.361757171439812 0.800729739136524 GO:0017080 sodium channel regulator activity 7/2651 41/18639 0.170731707317073 1.20040297724743 0.364095879045554 0.804430713045835 GO:0030971 receptor tyrosine kinase binding 13/2651 81/18639 0.160493827160494 1.12842114086927 0.364650824364741 0.804430713045835 GO:0051959 dynein light intermediate chain binding 5/2651 28/18639 0.178571428571429 1.25552352212103 0.367040514937683 0.808348425038343 GO:0016651 oxidoreductase activity, acting on NAD(P)H 14/2651 88/18639 0.159090909090909 1.11855731970783 0.369322706245846 0.812016701378596 GO:0008238 exopeptidase activity 16/2651 102/18639 0.156862745098039 1.10289125080436 0.377193848776272 0.827940498063917 GO:0043015 gamma-tubulin binding 6/2651 35/18639 0.171428571428571 1.20530258123619 0.379496730518666 0.83022789716459 GO:0061631 ubiquitin conjugating enzyme activity 6/2651 35/18639 0.171428571428571 1.20530258123619 0.379496730518666 0.83022789716459 GO:0008374 O-acyltransferase activity 9/2651 55/18639 0.163636363636364 1.15051610027091 0.380381212395313 0.830782846972848 GO:0016881 acid-amino acid ligase activity 4/2651 22/18639 0.181818181818182 1.27835122252323 0.383526286434678 0.832131992149046 GO:0030021 extracellular matrix structural constituent conferring compression resistance 4/2651 22/18639 0.181818181818182 1.27835122252323 0.383526286434678 0.832131992149046 GO:0050321 tau-protein kinase activity 4/2651 22/18639 0.181818181818182 1.27835122252323 0.383526286434678 0.832131992149046 GO:0140035 ubiquitin-like protein reader activity 4/2651 22/18639 0.181818181818182 1.27835122252323 0.383526286434678 0.832131992149046 GO:0019894 kinesin binding 7/2651 42/18639 0.166666666666667 1.17182195397963 0.388769705220757 0.839360166845471 GO:0043175 RNA polymerase core enzyme binding 7/2651 42/18639 0.166666666666667 1.17182195397963 0.388769705220757 0.839360166845471 GO:0048487 beta-tubulin binding 7/2651 42/18639 0.166666666666667 1.17182195397963 0.388769705220757 0.839360166845471 GO:0016922 nuclear receptor binding 21/2651 137/18639 0.153284671532847 1.07773405986448 0.391259433012911 0.84246864712284 GO:0016279 protein-lysine N-methyltransferase activity 11/2651 69/18639 0.159420289855072 1.12087317337182 0.391488847410158 0.84246864712284 GO:0035254 glutamate receptor binding 8/2651 49/18639 0.163265306122449 1.14790722022494 0.396001324466165 0.848066866804725 GO:0003785 actin monomer binding 5/2651 29/18639 0.172413793103448 1.21222960756513 0.397059843447585 0.848066866804725 GO:0004629 phospholipase C activity 5/2651 29/18639 0.172413793103448 1.21222960756513 0.397059843447585 0.848066866804725 GO:0010484 histone H3 acetyltransferase activity 5/2651 29/18639 0.172413793103448 1.21222960756513 0.397059843447585 0.848066866804725 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 13/2651 83/18639 0.156626506024096 1.10123027000495 0.39964597058503 0.848066866804725 GO:0004707 MAP kinase activity 3/2651 16/18639 0.1875 1.31829969822708 0.402887902227877 0.848066866804725 GO:0008142 oxysterol binding 3/2651 16/18639 0.1875 1.31829969822708 0.402887902227877 0.848066866804725 GO:0016675 oxidoreductase activity, acting on a heme group of donors 3/2651 16/18639 0.1875 1.31829969822708 0.402887902227877 0.848066866804725 GO:0022841 potassium ion leak channel activity 3/2651 16/18639 0.1875 1.31829969822708 0.402887902227877 0.848066866804725 GO:0022858 alanine transmembrane transporter activity 3/2651 16/18639 0.1875 1.31829969822708 0.402887902227877 0.848066866804725 GO:0061809 NAD+ nucleosidase activity, cyclic ADP-ribose generating 3/2651 16/18639 0.1875 1.31829969822708 0.402887902227877 0.848066866804725 GO:0000993 RNA polymerase II complex binding 6/2651 36/18639 0.166666666666667 1.17182195397963 0.406465798808065 0.848066866804725 GO:0008194 UDP-glycosyltransferase activity 22/2651 145/18639 0.151724137931034 1.06676205465732 0.406715859412708 0.848066866804725 GO:0016278 lysine N-methyltransferase activity 11/2651 70/18639 0.157142857142857 1.10486069946651 0.410723446874526 0.848066866804725 GO:0016782 transferase activity, transferring sulphur-containing groups 11/2651 70/18639 0.157142857142857 1.10486069946651 0.410723446874526 0.848066866804725 GO:0004712 protein serine/threonine/tyrosine kinase activity 7/2651 43/18639 0.162790697674419 1.14457028063127 0.413463211725491 0.848066866804725 GO:0008200 ion channel inhibitor activity 7/2651 43/18639 0.162790697674419 1.14457028063127 0.413463211725491 0.848066866804725 GO:0008375 acetylglucosaminyltransferase activity 7/2651 43/18639 0.162790697674419 1.14457028063127 0.413463211725491 0.848066866804725 GO:0008171 O-methyltransferase activity 4/2651 23/18639 0.173913043478261 1.22277073458744 0.417708129455978 0.848066866804725 GO:0016849 phosphorus-oxygen lyase activity 4/2651 23/18639 0.173913043478261 1.22277073458744 0.417708129455978 0.848066866804725 GO:0032813 tumor necrosis factor receptor superfamily binding 8/2651 50/18639 0.16 1.12494907582045 0.418913478340422 0.848066866804725 GO:0005200 structural constituent of cytoskeleton 17/2651 112/18639 0.151785714285714 1.06719499380288 0.426232730807254 0.848066866804725 GO:0003680 minor groove of adenine-thymine-rich DNA binding 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0004090 carbonyl reductase (NADPH) activity 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0004382 GDP phosphatase activity 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0004862 cAMP-dependent protein kinase inhibitor activity 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0004935 adrenergic receptor activity 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0004955 prostaglandin receptor activity 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0005381 iron ion transmembrane transporter activity 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0005528 FK506 binding 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0015203 polyamine transmembrane transporter activity 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0016175 superoxide-generating NAD(P)H oxidase activity 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0016303 1-phosphatidylinositol-3-kinase activity 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0016783 sulfurtransferase activity 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0019911 structural constituent of myelin sheath 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0031434 mitogen-activated protein kinase kinase binding 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0033204 ribonuclease P RNA binding 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0035374 chondroitin sulfate binding 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0042166 acetylcholine binding 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0043121 neurotrophin binding 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0043295 glutathione binding 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0045322 unmethylated CpG binding 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0050815 phosphoserine residue binding 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0071723 lipopeptide binding 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0098505 G-rich strand telomeric DNA binding 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:1990757 ubiquitin ligase activator activity 2/2651 10/18639 0.2 1.40618634477556 0.426849988278885 0.848066866804725 GO:0031624 ubiquitin conjugating enzyme binding 5/2651 30/18639 0.166666666666667 1.17182195397963 0.426931156181878 0.848066866804725 GO:0016248 channel inhibitor activity 7/2651 44/18639 0.159090909090909 1.11855731970783 0.438080777080771 0.868904191890626 GO:0032182 ubiquitin-like protein binding 18/2651 120/18639 0.15 1.05463975858167 0.442774238183624 0.869908140274204 GO:0008484 sulfuric ester hydrolase activity 3/2651 17/18639 0.176470588235294 1.2407526571549 0.443210601460889 0.869908140274204 GO:0016805 dipeptidase activity 3/2651 17/18639 0.176470588235294 1.2407526571549 0.443210601460889 0.869908140274204 GO:0030169 low-density lipoprotein particle binding 3/2651 17/18639 0.176470588235294 1.2407526571549 0.443210601460889 0.869908140274204 GO:0031489 myosin V binding 3/2651 17/18639 0.176470588235294 1.2407526571549 0.443210601460889 0.869908140274204 GO:0032183 SUMO binding 3/2651 17/18639 0.176470588235294 1.2407526571549 0.443210601460889 0.869908140274204 GO:1990226 histone methyltransferase binding 3/2651 17/18639 0.176470588235294 1.2407526571549 0.443210601460889 0.869908140274204 GO:0019783 ubiquitin-like protein peptidase activity 19/2651 127/18639 0.149606299212598 1.05187167522581 0.44391485834096 0.869993851837863 GO:0008186 ATP-dependent activity, acting on RNA 12/2651 79/18639 0.151898734177215 1.06798962894346 0.450927915134585 0.874309632339446 GO:0015370 solute:sodium symporter activity 12/2651 79/18639 0.151898734177215 1.06798962894346 0.450927915134585 0.874309632339446 GO:0001091 RNA polymerase II general transcription initiation factor binding 4/2651 24/18639 0.166666666666667 1.17182195397963 0.45142790432105 0.874309632339446 GO:0004622 lysophospholipase activity 4/2651 24/18639 0.166666666666667 1.17182195397963 0.45142790432105 0.874309632339446 GO:0015149 hexose transmembrane transporter activity 4/2651 24/18639 0.166666666666667 1.17182195397963 0.45142790432105 0.874309632339446 GO:0043998 histone H2A acetyltransferase activity 4/2651 24/18639 0.166666666666667 1.17182195397963 0.45142790432105 0.874309632339446 GO:0055056 D-glucose transmembrane transporter activity 4/2651 24/18639 0.166666666666667 1.17182195397963 0.45142790432105 0.874309632339446 GO:0070840 dynein complex binding 4/2651 24/18639 0.166666666666667 1.17182195397963 0.45142790432105 0.874309632339446 GO:0005452 solute:inorganic anion antiporter activity 5/2651 31/18639 0.161290322580645 1.13402124578674 0.456497232471112 0.874366594852647 GO:0016878 acid-thiol ligase activity 5/2651 31/18639 0.161290322580645 1.13402124578674 0.456497232471112 0.874366594852647 GO:0031490 chromatin DNA binding 19/2651 128/18639 0.1484375 1.04365392776311 0.458330252979084 0.874366594852647 GO:0008509 monoatomic anion transmembrane transporter activity 22/2651 149/18639 0.147651006711409 1.03812414714974 0.460140415302915 0.874366594852647 GO:0141110 transporter inhibitor activity 7/2651 45/18639 0.155555555555556 1.09370049038099 0.462532299899881 0.874366594852647 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 8/2651 52/18639 0.153846153846154 1.0816818036735 0.464490890127971 0.874366594852647 GO:0001786 phosphatidylserine binding 9/2651 59/18639 0.152542372881356 1.07251500872712 0.466041923438146 0.874366594852647 GO:0004879 nuclear receptor activity 9/2651 59/18639 0.152542372881356 1.07251500872712 0.466041923438146 0.874366594852647 GO:0015459 potassium channel regulator activity 9/2651 59/18639 0.152542372881356 1.07251500872712 0.466041923438146 0.874366594852647 GO:0031593 polyubiquitin modification-dependent protein binding 9/2651 59/18639 0.152542372881356 1.07251500872712 0.466041923438146 0.874366594852647 GO:0004843 cysteine-type deubiquitinase activity 16/2651 108/18639 0.148148148148148 1.04161951464856 0.471612008880297 0.874366594852647 GO:0101005 deubiquitinase activity 17/2651 115/18639 0.147826086956522 1.03935512439932 0.472029245770846 0.874366594852647 GO:0002020 protease binding 20/2651 136/18639 0.147058823529412 1.03396054762909 0.473005800733088 0.874366594852647 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.874366594852647 GO:0002162 dystroglycan binding 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.874366594852647 GO:0004954 prostanoid receptor activity 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.874366594852647 GO:0005114 type II transforming growth factor beta receptor binding 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.874366594852647 GO:0005225 volume-sensitive anion channel activity 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.874366594852647 GO:0008046 axon guidance receptor activity 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.874366594852647 GO:0008172 S-methyltransferase activity 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.874366594852647 GO:0008271 secondary active sulfate transmembrane transporter activity 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.874366594852647 GO:0008432 JUN kinase binding 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.874366594852647 GO:0008503 benzodiazepine receptor activity 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.874366594852647 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.874366594852647 GO:0016594 glycine binding 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.874366594852647 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.874366594852647 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.874366594852647 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.874366594852647 GO:0032050 clathrin heavy chain binding 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.874366594852647 GO:0034511 U3 snoRNA binding 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.874366594852647 GO:0034713 type I transforming growth factor beta receptor binding 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.874366594852647 GO:0042608 T cell receptor binding 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.874366594852647 GO:0043522 leucine zipper domain binding 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.874366594852647 GO:0070990 snRNP binding 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.874366594852647 GO:0099528 G protein-coupled neurotransmitter receptor activity 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.874366594852647 GO:0140937 histone H4K12 deacetylase activity, hydrolytic mechanism 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.874366594852647 GO:1900750 oligopeptide binding 2/2651 11/18639 0.181818181818182 1.27835122252323 0.477719533465872 0.874366594852647 GO:0004706 JUN kinase kinase kinase activity 3/2651 18/18639 0.166666666666667 1.17182195397963 0.482411373158589 0.874366594852647 GO:0016854 racemase and epimerase activity 3/2651 18/18639 0.166666666666667 1.17182195397963 0.482411373158589 0.874366594852647 GO:0000030 mannosyltransferase activity 4/2651 25/18639 0.16 1.12494907582045 0.48448495447541 0.874366594852647 GO:0001848 complement binding 4/2651 25/18639 0.16 1.12494907582045 0.48448495447541 0.874366594852647 GO:0003707 nuclear steroid receptor activity 4/2651 25/18639 0.16 1.12494907582045 0.48448495447541 0.874366594852647 GO:0004709 MAP kinase kinase kinase activity 4/2651 25/18639 0.16 1.12494907582045 0.48448495447541 0.874366594852647 GO:0017025 TBP-class protein binding 4/2651 25/18639 0.16 1.12494907582045 0.48448495447541 0.874366594852647 GO:0047617 fatty acyl-CoA hydrolase activity 4/2651 25/18639 0.16 1.12494907582045 0.48448495447541 0.874366594852647 GO:0071813 lipoprotein particle binding 5/2651 32/18639 0.15625 1.0985830818559 0.485616418567079 0.874366594852647 GO:0071814 protein-lipid complex binding 5/2651 32/18639 0.15625 1.0985830818559 0.485616418567079 0.874366594852647 GO:0005246 calcium channel regulator activity 8/2651 53/18639 0.150943396226415 1.06127271303816 0.487015193827293 0.874366594852647 GO:0005544 calcium-dependent phospholipid binding 8/2651 53/18639 0.150943396226415 1.06127271303816 0.487015193827293 0.874366594852647 GO:0008146 sulfotransferase activity 8/2651 53/18639 0.150943396226415 1.06127271303816 0.487015193827293 0.874366594852647 GO:0017046 peptide hormone binding 8/2651 53/18639 0.150943396226415 1.06127271303816 0.487015193827293 0.874366594852647 GO:0051018 protein kinase A binding 8/2651 53/18639 0.150943396226415 1.06127271303816 0.487015193827293 0.874366594852647 GO:0098531 ligand-modulated transcription factor activity 9/2651 60/18639 0.15 1.05463975858167 0.487196358025342 0.874366594852647 GO:0042054 histone methyltransferase activity 10/2651 67/18639 0.149253731343284 1.04939279460862 0.487308337602007 0.874366594852647 GO:0001217 DNA-binding transcription repressor activity 40/2651 278/18639 0.143884892086331 1.01164485235652 0.494716564388303 0.886451313332511 GO:0031072 heat shock protein binding 19/2651 131/18639 0.145038167938931 1.01975345613495 0.501346717586844 0.887655844392549 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 50/2651 349/18639 0.143266475644699 1.00729680857848 0.501399159478881 0.887655844392549 GO:0004722 protein serine/threonine phosphatase activity 15/2651 103/18639 0.145631067961165 1.02392209571036 0.503435695962221 0.887655844392549 GO:0005548 phospholipid transporter activity 10/2651 68/18639 0.147058823529412 1.03396054762909 0.507134569063382 0.887655844392549 GO:0030145 manganese ion binding 10/2651 68/18639 0.147058823529412 1.03396054762909 0.507134569063382 0.887655844392549 GO:0016836 hydro-lyase activity 9/2651 61/18639 0.147540983606557 1.03735058221148 0.508134279500961 0.887655844392549 GO:0050661 NADP binding 8/2651 54/18639 0.148148148148148 1.04161951464856 0.509276647768257 0.887655844392549 GO:0140938 histone H3 methyltransferase activity 7/2651 47/18639 0.148936170212766 1.0471600439818 0.510607673774776 0.887655844392549 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 24/2651 167/18639 0.143712574850299 1.01043330163513 0.511936111130005 0.887655844392549 GO:0015144 carbohydrate transmembrane transporter activity 6/2651 40/18639 0.15 1.05463975858167 0.5121979923032 0.887655844392549 GO:0061791 GTPase motor activity 6/2651 40/18639 0.15 1.05463975858167 0.5121979923032 0.887655844392549 GO:1990606 membrane scission GTPase motor activity 6/2651 40/18639 0.15 1.05463975858167 0.5121979923032 0.887655844392549 GO:0099106 ion channel regulator activity 23/2651 160/18639 0.14375 1.01069643530743 0.512580966634466 0.887655844392549 GO:0015145 monosaccharide transmembrane transporter activity 4/2651 26/18639 0.153846153846154 1.0816818036735 0.516707885395848 0.887655844392549 GO:0016289 acyl-CoA hydrolase activity 4/2651 26/18639 0.153846153846154 1.0816818036735 0.516707885395848 0.887655844392549 GO:0050681 nuclear androgen receptor binding 4/2651 26/18639 0.153846153846154 1.0816818036735 0.516707885395848 0.887655844392549 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 3/2651 19/18639 0.157894736842105 1.11014711429649 0.520240875715824 0.887655844392549 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 3/2651 19/18639 0.157894736842105 1.11014711429649 0.520240875715824 0.887655844392549 GO:0022840 leak channel activity 3/2651 19/18639 0.157894736842105 1.11014711429649 0.520240875715824 0.887655844392549 GO:0022842 narrow pore channel activity 3/2651 19/18639 0.157894736842105 1.11014711429649 0.520240875715824 0.887655844392549 GO:0030506 ankyrin binding 3/2651 19/18639 0.157894736842105 1.11014711429649 0.520240875715824 0.887655844392549 GO:0031420 alkali metal ion binding 3/2651 19/18639 0.157894736842105 1.11014711429649 0.520240875715824 0.887655844392549 GO:0042577 lipid phosphatase activity 3/2651 19/18639 0.157894736842105 1.11014711429649 0.520240875715824 0.887655844392549 GO:0042800 histone H3K4 methyltransferase activity 3/2651 19/18639 0.157894736842105 1.11014711429649 0.520240875715824 0.887655844392549 GO:0070003 threonine-type peptidase activity 3/2651 19/18639 0.157894736842105 1.11014711429649 0.520240875715824 0.887655844392549 GO:0097001 ceramide binding 3/2651 19/18639 0.157894736842105 1.11014711429649 0.520240875715824 0.887655844392549 GO:1990380 K48-linked deubiquitinase activity 3/2651 19/18639 0.157894736842105 1.11014711429649 0.520240875715824 0.887655844392549 GO:0017022 myosin binding 11/2651 76/18639 0.144736842105263 1.01763485477178 0.524928054533535 0.887655844392549 GO:0000340 RNA 7-methylguanosine cap binding 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.887655844392549 GO:0004032 aldose reductase (NADPH) activity 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.887655844392549 GO:0004526 ribonuclease P activity 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.887655844392549 GO:0004875 complement receptor activity 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.887655844392549 GO:0005247 voltage-gated chloride channel activity 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.887655844392549 GO:0005436 sodium:phosphate symporter activity 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.887655844392549 GO:0005527 macrolide binding 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.887655844392549 GO:0008504 monoamine transmembrane transporter activity 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.887655844392549 GO:0008603 cAMP-dependent protein kinase regulator activity 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.887655844392549 GO:0010853 cyclase activator activity 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.887655844392549 GO:0015166 polyol transmembrane transporter activity 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.887655844392549 GO:0016208 AMP binding 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.887655844392549 GO:0035197 siRNA binding 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.887655844392549 GO:0035251 UDP-glucosyltransferase activity 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.887655844392549 GO:0097677 STAT family protein binding 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.887655844392549 GO:0141221 histone deacetylase activity, hydrolytic mechanism 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.887655844392549 GO:1990459 transferrin receptor binding 2/2651 12/18639 0.166666666666667 1.17182195397963 0.525718723330439 0.887655844392549 GO:0008168 methyltransferase activity 29/2651 204/18639 0.142156862745098 0.999495196041449 0.531985023267977 0.89708614038915 GO:0043022 ribosome binding 16/2651 112/18639 0.142857142857143 1.00441881769683 0.533691619457914 0.898324057990364 GO:0032266 phosphatidylinositol-3-phosphate binding 7/2651 48/18639 0.145833333333333 1.02534420973218 0.534083323771037 0.898324057990364 GO:0001727 lipid kinase activity 6/2651 41/18639 0.146341463414634 1.02891683764065 0.537586926004511 0.900765879831986 GO:0015175 neutral L-amino acid transmembrane transporter activity 6/2651 41/18639 0.146341463414634 1.02891683764065 0.537586926004511 0.900765879831986 GO:0061650 ubiquitin-like protein conjugating enzyme activity 6/2651 41/18639 0.146341463414634 1.02891683764065 0.537586926004511 0.900765879831986 GO:0061134 peptidase regulator activity 32/2651 226/18639 0.141592920353982 0.995530155593314 0.540294055175201 0.904151551036519 GO:0003724 RNA helicase activity 11/2651 77/18639 0.142857142857143 1.00441881769683 0.543381158468701 0.90816368744071 GO:0008028 monocarboxylic acid transmembrane transporter activity 10/2651 70/18639 0.142857142857143 1.00441881769683 0.546070887495214 0.911180398820929 GO:0008266 poly(U) RNA binding 4/2651 27/18639 0.148148148148148 1.04161951464856 0.547953588357005 0.911180398820929 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 4/2651 27/18639 0.148148148148148 1.04161951464856 0.547953588357005 0.911180398820929 GO:0023026 MHC class II protein complex binding 4/2651 27/18639 0.148148148148148 1.04161951464856 0.547953588357005 0.911180398820929 GO:0010851 cyclase regulator activity 3/2651 20/18639 0.15 1.05463975858167 0.556508151516794 0.918268756262672 GO:0015464 acetylcholine receptor activity 3/2651 20/18639 0.15 1.05463975858167 0.556508151516794 0.918268756262672 GO:0016408 C-acyltransferase activity 3/2651 20/18639 0.15 1.05463975858167 0.556508151516794 0.918268756262672 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 3/2651 20/18639 0.15 1.05463975858167 0.556508151516794 0.918268756262672 GO:0030742 GTP-dependent protein binding 3/2651 20/18639 0.15 1.05463975858167 0.556508151516794 0.918268756262672 GO:0140939 histone H4 methyltransferase activity 3/2651 20/18639 0.15 1.05463975858167 0.556508151516794 0.918268756262672 GO:0060590 ATPase regulator activity 7/2651 49/18639 0.142857142857143 1.00441881769683 0.557096990321849 0.918268756262672 GO:0005319 lipid transporter activity 25/2651 178/18639 0.140449438202247 0.987490410656992 0.560142459592484 0.920987809868855 GO:0015108 chloride transmembrane transporter activity 17/2651 121/18639 0.140495867768595 0.987816853767953 0.561622996067821 0.920987809868855 GO:0031492 nucleosomal DNA binding 6/2651 42/18639 0.142857142857143 1.00441881769683 0.562389796135137 0.920987809868855 GO:0005343 organic acid:sodium symporter activity 5/2651 35/18639 0.142857142857143 1.00441881769683 0.569115984659244 0.920987809868855 GO:0043130 ubiquitin binding 14/2651 100/18639 0.14 0.984330441342889 0.569214669254391 0.920987809868855 GO:0003964 RNA-directed DNA polymerase activity 2/2651 13/18639 0.153846153846154 1.0816818036735 0.570634816137423 0.920987809868855 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 2/2651 13/18639 0.153846153846154 1.0816818036735 0.570634816137423 0.920987809868855 GO:0005338 nucleotide-sugar transmembrane transporter activity 2/2651 13/18639 0.153846153846154 1.0816818036735 0.570634816137423 0.920987809868855 GO:0008417 fucosyltransferase activity 2/2651 13/18639 0.153846153846154 1.0816818036735 0.570634816137423 0.920987809868855 GO:0009982 pseudouridine synthase activity 2/2651 13/18639 0.153846153846154 1.0816818036735 0.570634816137423 0.920987809868855 GO:0039706 co-receptor binding 2/2651 13/18639 0.153846153846154 1.0816818036735 0.570634816137423 0.920987809868855 GO:0045028 G protein-coupled purinergic nucleotide receptor activity 2/2651 13/18639 0.153846153846154 1.0816818036735 0.570634816137423 0.920987809868855 GO:0045159 myosin II binding 2/2651 13/18639 0.153846153846154 1.0816818036735 0.570634816137423 0.920987809868855 GO:0046974 histone H3K9 methyltransferase activity 2/2651 13/18639 0.153846153846154 1.0816818036735 0.570634816137423 0.920987809868855 GO:0046975 histone H3K36 methyltransferase activity 2/2651 13/18639 0.153846153846154 1.0816818036735 0.570634816137423 0.920987809868855 GO:0140333 glycerophospholipid flippase activity 2/2651 13/18639 0.153846153846154 1.0816818036735 0.570634816137423 0.920987809868855 GO:1901338 catecholamine binding 2/2651 13/18639 0.153846153846154 1.0816818036735 0.570634816137423 0.920987809868855 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 17/2651 122/18639 0.139344262295082 0.979719994310838 0.576069280744024 0.925109715044613 GO:0036408 histone H3K14 acetyltransferase activity 4/2651 28/18639 0.142857142857143 1.00441881769683 0.578105767260225 0.925109715044613 GO:0046625 sphingolipid binding 4/2651 28/18639 0.142857142857143 1.00441881769683 0.578105767260225 0.925109715044613 GO:0046875 ephrin receptor binding 4/2651 28/18639 0.142857142857143 1.00441881769683 0.578105767260225 0.925109715044613 GO:0046966 nuclear thyroid hormone receptor binding 4/2651 28/18639 0.142857142857143 1.00441881769683 0.578105767260225 0.925109715044613 GO:0050698 proteoglycan sulfotransferase activity 4/2651 28/18639 0.142857142857143 1.00441881769683 0.578105767260225 0.925109715044613 GO:0051119 sugar transmembrane transporter activity 4/2651 28/18639 0.142857142857143 1.00441881769683 0.578105767260225 0.925109715044613 GO:0016798 hydrolase activity, acting on glycosyl bonds 18/2651 130/18639 0.138461538461538 0.973513623306154 0.587464779820419 0.936756388414683 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 18/2651 130/18639 0.138461538461538 0.973513623306154 0.587464779820419 0.936756388414683 GO:0004857 enzyme inhibitor activity 58/2651 416/18639 0.139423076923077 0.980274134579114 0.587555492384289 0.936756388414683 GO:0016410 N-acyltransferase activity 13/2651 94/18639 0.138297872340426 0.972362897983097 0.588583152277331 0.936756388414683 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 3/2651 21/18639 0.142857142857143 1.00441881769683 0.591074076516781 0.936756388414683 GO:0008373 sialyltransferase activity 3/2651 21/18639 0.142857142857143 1.00441881769683 0.591074076516781 0.936756388414683 GO:0009975 cyclase activity 3/2651 21/18639 0.142857142857143 1.00441881769683 0.591074076516781 0.936756388414683 GO:0035613 RNA stem-loop binding 3/2651 21/18639 0.142857142857143 1.00441881769683 0.591074076516781 0.936756388414683 GO:0045505 dynein intermediate chain binding 5/2651 36/18639 0.138888888888889 0.976518294983025 0.595349885602982 0.938975514904891 GO:0030544 Hsp70 protein binding 7/2651 51/18639 0.137254901960784 0.965029844453813 0.601518597845512 0.938975514904891 GO:0004521 RNA endonuclease activity 10/2651 73/18639 0.136986301369863 0.963141332038052 0.602125135824706 0.938975514904891 GO:0004867 serine-type endopeptidase inhibitor activity 13/2651 95/18639 0.136842105263158 0.96212749905696 0.604628887506145 0.938975514904891 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 37/2651 268/18639 0.138059701492537 0.970688335012977 0.604837288484976 0.938975514904891 GO:0099604 ligand-gated calcium channel activity 4/2651 29/18639 0.137931034482759 0.969783686052108 0.607073115070248 0.938975514904891 GO:0106222 lncRNA binding 4/2651 29/18639 0.137931034482759 0.969783686052108 0.607073115070248 0.938975514904891 GO:0043014 alpha-tubulin binding 6/2651 44/18639 0.136363636363636 0.958763416892425 0.609980991379955 0.938975514904891 GO:0016247 channel regulator activity 23/2651 168/18639 0.136904761904762 0.962568033626125 0.612346279311238 0.938975514904891 GO:0004065 arylsulfatase activity 2/2651 14/18639 0.142857142857143 1.00441881769683 0.612373592543626 0.938975514904891 GO:0008174 mRNA methyltransferase activity 2/2651 14/18639 0.142857142857143 1.00441881769683 0.612373592543626 0.938975514904891 GO:0008195 phosphatidate phosphatase activity 2/2651 14/18639 0.142857142857143 1.00441881769683 0.612373592543626 0.938975514904891 GO:0008559 ABC-type xenobiotic transporter activity 2/2651 14/18639 0.142857142857143 1.00441881769683 0.612373592543626 0.938975514904891 GO:0015926 glucosidase activity 2/2651 14/18639 0.142857142857143 1.00441881769683 0.612373592543626 0.938975514904891 GO:0019992 diacylglycerol binding 2/2651 14/18639 0.142857142857143 1.00441881769683 0.612373592543626 0.938975514904891 GO:0044548 S100 protein binding 2/2651 14/18639 0.142857142857143 1.00441881769683 0.612373592543626 0.938975514904891 GO:0052816 long-chain fatty acyl-CoA hydrolase activity 2/2651 14/18639 0.142857142857143 1.00441881769683 0.612373592543626 0.938975514904891 GO:0071933 Arp2/3 complex binding 2/2651 14/18639 0.142857142857143 1.00441881769683 0.612373592543626 0.938975514904891 GO:0033192 calmodulin-dependent protein phosphatase activity 11/2651 81/18639 0.135802469135802 0.954817888427847 0.614278970233293 0.938975514904891 GO:0140791 histone H2AXS140 phosphatase activity 11/2651 81/18639 0.135802469135802 0.954817888427847 0.614278970233293 0.938975514904891 GO:0180004 RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity 11/2651 81/18639 0.135802469135802 0.954817888427847 0.614278970233293 0.938975514904891 GO:0180005 RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity 11/2651 81/18639 0.135802469135802 0.954817888427847 0.614278970233293 0.938975514904891 GO:0180006 RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity 11/2651 81/18639 0.135802469135802 0.954817888427847 0.614278970233293 0.938975514904891 GO:0180007 RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity 11/2651 81/18639 0.135802469135802 0.954817888427847 0.614278970233293 0.938975514904891 GO:0180008 RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity 11/2651 81/18639 0.135802469135802 0.954817888427847 0.614278970233293 0.938975514904891 GO:1990439 MAP kinase serine/threonine phosphatase activity 11/2651 81/18639 0.135802469135802 0.954817888427847 0.614278970233293 0.938975514904891 GO:0004896 cytokine receptor activity 13/2651 96/18639 0.135416666666667 0.95210533760845 0.620381866505102 0.938975514904891 GO:0022829 wide pore channel activity 5/2651 37/18639 0.135135135135135 0.950125908632133 0.620665219260411 0.938975514904891 GO:0043394 proteoglycan binding 5/2651 37/18639 0.135135135135135 0.950125908632133 0.620665219260411 0.938975514904891 GO:0005243 gap junction channel activity 3/2651 22/18639 0.136363636363636 0.958763416892425 0.623844780213956 0.938975514904891 GO:0032931 histone H3K56 acetyltransferase activity 3/2651 22/18639 0.136363636363636 0.958763416892425 0.623844780213956 0.938975514904891 GO:0043992 histone H3K9 acetyltransferase activity 3/2651 22/18639 0.136363636363636 0.958763416892425 0.623844780213956 0.938975514904891 GO:0043993 histone H3K18 acetyltransferase activity 3/2651 22/18639 0.136363636363636 0.958763416892425 0.623844780213956 0.938975514904891 GO:0043994 histone H3K23 acetyltransferase activity 3/2651 22/18639 0.136363636363636 0.958763416892425 0.623844780213956 0.938975514904891 GO:0043999 histone H2AK5 acetyltransferase activity 3/2651 22/18639 0.136363636363636 0.958763416892425 0.623844780213956 0.938975514904891 GO:0044012 histone H2AK9 acetyltransferase activity 3/2651 22/18639 0.136363636363636 0.958763416892425 0.623844780213956 0.938975514904891 GO:0044014 histone H2BK5 acetyltransferase activity 3/2651 22/18639 0.136363636363636 0.958763416892425 0.623844780213956 0.938975514904891 GO:0044015 histone H2BK12 acetyltransferase activity 3/2651 22/18639 0.136363636363636 0.958763416892425 0.623844780213956 0.938975514904891 GO:0044016 histone H3K4 acetyltransferase activity 3/2651 22/18639 0.136363636363636 0.958763416892425 0.623844780213956 0.938975514904891 GO:0044017 histone H3K27 acetyltransferase activity 3/2651 22/18639 0.136363636363636 0.958763416892425 0.623844780213956 0.938975514904891 GO:0044018 histone H3K36 acetyltransferase activity 3/2651 22/18639 0.136363636363636 0.958763416892425 0.623844780213956 0.938975514904891 GO:0046972 histone H4K16 acetyltransferase activity 3/2651 22/18639 0.136363636363636 0.958763416892425 0.623844780213956 0.938975514904891 GO:0140517 protein-RNA adaptor activity 3/2651 22/18639 0.136363636363636 0.958763416892425 0.623844780213956 0.938975514904891 GO:0140908 histone H3K122 acetyltransferase activity 3/2651 22/18639 0.136363636363636 0.958763416892425 0.623844780213956 0.938975514904891 GO:0003727 single-stranded RNA binding 12/2651 89/18639 0.134831460674157 0.947990794230712 0.625457842584611 0.940328742789878 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 9/2651 67/18639 0.134328358208955 0.944453515147762 0.626677289419064 0.941087788101376 GO:0008420 RNA polymerase II CTD heptapeptide repeat phosphatase activity 11/2651 82/18639 0.134146341463415 0.943173767837263 0.631140350127513 0.944649519585369 GO:0033549 MAP kinase phosphatase activity 11/2651 82/18639 0.134146341463415 0.943173767837263 0.631140350127513 0.944649519585369 GO:0005217 intracellularly ligand-gated monoatomic ion channel activity 4/2651 30/18639 0.133333333333333 0.937457563183704 0.634787262591535 0.944649519585369 GO:0008187 poly-pyrimidine tract binding 4/2651 30/18639 0.133333333333333 0.937457563183704 0.634787262591535 0.944649519585369 GO:0043995 histone H4K5 acetyltransferase activity 4/2651 30/18639 0.133333333333333 0.937457563183704 0.634787262591535 0.944649519585369 GO:0043996 histone H4K8 acetyltransferase activity 4/2651 30/18639 0.133333333333333 0.937457563183704 0.634787262591535 0.944649519585369 GO:0043997 histone H4K12 acetyltransferase activity 4/2651 30/18639 0.133333333333333 0.937457563183704 0.634787262591535 0.944649519585369 GO:0098918 structural constituent of synapse 4/2651 30/18639 0.133333333333333 0.937457563183704 0.634787262591535 0.944649519585369 GO:0141108 transporter regulator activity 23/2651 170/18639 0.135294117647059 0.951243703818759 0.635917923565516 0.945264001507657 GO:0019003 GDP binding 10/2651 75/18639 0.133333333333333 0.937457563183704 0.63756465505866 0.945532753178748 GO:0004864 protein phosphatase inhibitor activity 7/2651 53/18639 0.132075471698113 0.928613623908386 0.64350210114452 0.945532753178748 GO:0015081 sodium ion transmembrane transporter activity 22/2651 164/18639 0.134146341463415 0.943173767837263 0.650811727433099 0.945532753178748 GO:0004865 protein serine/threonine phosphatase inhibitor activity 2/2651 15/18639 0.133333333333333 0.937457563183704 0.650929965021136 0.945532753178748 GO:0005402 carbohydrate:monoatomic cation symporter activity 2/2651 15/18639 0.133333333333333 0.937457563183704 0.650929965021136 0.945532753178748 GO:0008020 G protein-coupled photoreceptor activity 2/2651 15/18639 0.133333333333333 0.937457563183704 0.650929965021136 0.945532753178748 GO:0008242 omega peptidase activity 2/2651 15/18639 0.133333333333333 0.937457563183704 0.650929965021136 0.945532753178748 GO:0015929 hexosaminidase activity 2/2651 15/18639 0.133333333333333 0.937457563183704 0.650929965021136 0.945532753178748 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 2/2651 15/18639 0.133333333333333 0.937457563183704 0.650929965021136 0.945532753178748 GO:0016846 carbon-sulfur lyase activity 2/2651 15/18639 0.133333333333333 0.937457563183704 0.650929965021136 0.945532753178748 GO:0045504 dynein heavy chain binding 2/2651 15/18639 0.133333333333333 0.937457563183704 0.650929965021136 0.945532753178748 GO:0047372 monoacylglycerol lipase activity 2/2651 15/18639 0.133333333333333 0.937457563183704 0.650929965021136 0.945532753178748 GO:0048531 beta-1,3-galactosyltransferase activity 2/2651 15/18639 0.133333333333333 0.937457563183704 0.650929965021136 0.945532753178748 GO:0120283 protein serine/threonine kinase binding 2/2651 15/18639 0.133333333333333 0.937457563183704 0.650929965021136 0.945532753178748 GO:0140161 monocarboxylate:sodium symporter activity 2/2651 15/18639 0.133333333333333 0.937457563183704 0.650929965021136 0.945532753178748 GO:0140776 protein-containing complex destabilizing activity 2/2651 15/18639 0.133333333333333 0.937457563183704 0.650929965021136 0.945532753178748 GO:0141050 histone H3K deacetylase activity 2/2651 15/18639 0.133333333333333 0.937457563183704 0.650929965021136 0.945532753178748 GO:0141051 histone H4K deacetylase activity 2/2651 15/18639 0.133333333333333 0.937457563183704 0.650929965021136 0.945532753178748 GO:0008170 N-methyltransferase activity 13/2651 98/18639 0.13265306122449 0.932674616432767 0.650939132219819 0.945532753178748 GO:0003950 NAD+ poly-ADP-ribosyltransferase activity 3/2651 23/18639 0.130434782608696 0.91707805094058 0.654765277827653 0.945532753178748 GO:0031681 G-protein beta-subunit binding 3/2651 23/18639 0.130434782608696 0.91707805094058 0.654765277827653 0.945532753178748 GO:0042171 lysophosphatidic acid acyltransferase activity 3/2651 23/18639 0.130434782608696 0.91707805094058 0.654765277827653 0.945532753178748 GO:0044013 histone H2B acetyltransferase activity 3/2651 23/18639 0.130434782608696 0.91707805094058 0.654765277827653 0.945532753178748 GO:0071617 lysophospholipid acyltransferase activity 3/2651 23/18639 0.130434782608696 0.91707805094058 0.654765277827653 0.945532753178748 GO:0099186 structural constituent of postsynapse 3/2651 23/18639 0.130434782608696 0.91707805094058 0.654765277827653 0.945532753178748 GO:1990404 NAD+-protein mono-ADP-ribosyltransferase activity 3/2651 23/18639 0.130434782608696 0.91707805094058 0.654765277827653 0.945532753178748 GO:0005164 tumor necrosis factor receptor binding 4/2651 31/18639 0.129032258064516 0.907216996629391 0.661200600387154 0.953780055542038 GO:0017018 myosin phosphatase activity 11/2651 84/18639 0.130952380952381 0.920717249555424 0.663674875706472 0.956301762916219 GO:0046982 protein heterodimerization activity 50/2651 369/18639 0.13550135501355 0.952700775593195 0.66821724251801 0.961794653984939 GO:0015179 L-amino acid transmembrane transporter activity 8/2651 62/18639 0.129032258064516 0.907216996629391 0.671899355512956 0.965343445391928 GO:0043178 alcohol binding 12/2651 92/18639 0.130434782608696 0.91707805094058 0.672148777087622 0.965343445391928 GO:0043495 protein-membrane adaptor activity 6/2651 47/18639 0.127659574468085 0.897565751984398 0.675620635865697 0.96821803855835 GO:0140359 ABC-type transporter activity 6/2651 47/18639 0.127659574468085 0.897565751984398 0.675620635865697 0.96821803855835 GO:0004806 triacylglycerol lipase activity 3/2651 24/18639 0.125 0.878866465484723 0.683813474042881 0.968855419419473 GO:0070696 transmembrane receptor protein serine/threonine kinase binding 3/2651 24/18639 0.125 0.878866465484723 0.683813474042881 0.968855419419473 GO:0008378 galactosyltransferase activity 4/2651 32/18639 0.125 0.878866465484723 0.686284054932878 0.968855419419473 GO:0005521 lamin binding 2/2651 16/18639 0.125 0.878866465484723 0.686364545420173 0.968855419419473 GO:0016722 oxidoreductase activity, acting on metal ions 2/2651 16/18639 0.125 0.878866465484723 0.686364545420173 0.968855419419473 GO:0017070 U6 snRNA binding 2/2651 16/18639 0.125 0.878866465484723 0.686364545420173 0.968855419419473 GO:0022848 acetylcholine-gated monoatomic cation-selective channel activity 2/2651 16/18639 0.125 0.878866465484723 0.686364545420173 0.968855419419473 GO:0030275 LRR domain binding 2/2651 16/18639 0.125 0.878866465484723 0.686364545420173 0.968855419419473 GO:0031435 mitogen-activated protein kinase kinase kinase binding 2/2651 16/18639 0.125 0.878866465484723 0.686364545420173 0.968855419419473 GO:0043023 ribosomal large subunit binding 2/2651 16/18639 0.125 0.878866465484723 0.686364545420173 0.968855419419473 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 2/2651 16/18639 0.125 0.878866465484723 0.686364545420173 0.968855419419473 GO:0070411 I-SMAD binding 2/2651 16/18639 0.125 0.878866465484723 0.686364545420173 0.968855419419473 GO:0097027 ubiquitin-protein transferase activator activity 2/2651 16/18639 0.125 0.878866465484723 0.686364545420173 0.968855419419473 GO:0140328 floppase activity 2/2651 16/18639 0.125 0.878866465484723 0.686364545420173 0.968855419419473 GO:0038187 pattern recognition receptor activity 6/2651 48/18639 0.125 0.878866465484723 0.69584025187922 0.981179455808279 GO:0016755 aminoacyltransferase activity 67/2651 496/18639 0.13508064516129 0.949742793346394 0.697194558381416 0.982037682768262 GO:0019212 phosphatase inhibitor activity 7/2651 56/18639 0.125 0.878866465484723 0.701355395996017 0.985789814863132 GO:0170055 lipid transmembrane transporter activity 7/2651 56/18639 0.125 0.878866465484723 0.701355395996017 0.985789814863132 GO:0140767 enzyme-substrate adaptor activity 18/2651 139/18639 0.129496402877698 0.910480367120864 0.70291530536486 0.986929058811855 GO:0061135 endopeptidase regulator activity 24/2651 184/18639 0.130434782608696 0.91707805094058 0.708536122112343 0.990209141085375 GO:0008081 phosphoric diester hydrolase activity 11/2651 87/18639 0.126436781609195 0.888968378881099 0.70927265775465 0.990209141085375 GO:0003924 GTPase activity 44/2651 331/18639 0.132930513595166 0.934625365107621 0.710723511165294 0.990209141085375 GO:0005251 delayed rectifier potassium channel activity 3/2651 25/18639 0.12 0.843711806865334 0.710994635802082 0.990209141085375 GO:0005537 D-mannose binding 3/2651 25/18639 0.12 0.843711806865334 0.710994635802082 0.990209141085375 GO:0015271 outward rectifier potassium channel activity 3/2651 25/18639 0.12 0.843711806865334 0.710994635802082 0.990209141085375 GO:0008227 G protein-coupled amine receptor activity 5/2651 41/18639 0.121951219512195 0.857430698033876 0.711919419840253 0.990209141085375 GO:0001222 transcription corepressor binding 6/2651 49/18639 0.122448979591837 0.860930415168708 0.715199776747691 0.990209141085375 GO:0004549 tRNA-specific ribonuclease activity 2/2651 17/18639 0.117647058823529 0.827168438103269 0.718785071281411 0.990209141085375 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 2/2651 17/18639 0.117647058823529 0.827168438103269 0.718785071281411 0.990209141085375 GO:0008429 phosphatidylethanolamine binding 2/2651 17/18639 0.117647058823529 0.827168438103269 0.718785071281411 0.990209141085375 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 2/2651 17/18639 0.117647058823529 0.827168438103269 0.718785071281411 0.990209141085375 GO:0009881 photoreceptor activity 2/2651 17/18639 0.117647058823529 0.827168438103269 0.718785071281411 0.990209141085375 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 2/2651 17/18639 0.117647058823529 0.827168438103269 0.718785071281411 0.990209141085375 GO:0032977 membrane insertase activity 2/2651 17/18639 0.117647058823529 0.827168438103269 0.718785071281411 0.990209141085375 GO:0045125 bioactive lipid receptor activity 2/2651 17/18639 0.117647058823529 0.827168438103269 0.718785071281411 0.990209141085375 GO:0046965 nuclear retinoid X receptor binding 2/2651 17/18639 0.117647058823529 0.827168438103269 0.718785071281411 0.990209141085375 GO:0070402 NADPH binding 2/2651 17/18639 0.117647058823529 0.827168438103269 0.718785071281411 0.990209141085375 GO:0005253 monoatomic anion channel activity 13/2651 103/18639 0.12621359223301 0.887399149615642 0.721162062914981 0.992445597553845 GO:0160215 deacylase activity 8/2651 65/18639 0.123076923076923 0.865345442938804 0.723568028344879 0.994717216419839 GO:0019787 ubiquitin-like protein transferase activity 64/2651 479/18639 0.133611691022964 0.939414677094317 0.727014747870741 0.998413371163469 GO:0042056 chemoattractant activity 5/2651 42/18639 0.119047619047619 0.837015681414021 0.73212612574635 0.999999999999821 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 4/2651 34/18639 0.117647058823529 0.827168438103269 0.732424531131008 0.999999999999821 GO:0051427 hormone receptor binding 4/2651 34/18639 0.117647058823529 0.827168438103269 0.732424531131008 0.999999999999821 GO:0001637 G protein-coupled chemoattractant receptor activity 3/2651 26/18639 0.115384615384615 0.811261352755129 0.736336385855069 0.999999999999821 GO:0004950 chemokine receptor activity 3/2651 26/18639 0.115384615384615 0.811261352755129 0.736336385855069 0.999999999999821 GO:0030507 spectrin binding 3/2651 26/18639 0.115384615384615 0.811261352755129 0.736336385855069 0.999999999999821 GO:0034237 protein kinase A regulatory subunit binding 3/2651 26/18639 0.115384615384615 0.811261352755129 0.736336385855069 0.999999999999821 GO:0052742 phosphatidylinositol kinase activity 3/2651 26/18639 0.115384615384615 0.811261352755129 0.736336385855069 0.999999999999821 GO:0097602 cullin family protein binding 3/2651 26/18639 0.115384615384615 0.811261352755129 0.736336385855069 0.999999999999821 GO:0008235 metalloexopeptidase activity 8/2651 66/18639 0.121212121212121 0.852234148348822 0.739514503021942 0.999999999999821 GO:0008308 voltage-gated monoatomic anion channel activity 2/2651 18/18639 0.111111111111111 0.78121463598642 0.748331783546764 0.999999999999821 GO:0008525 phosphatidylcholine transporter activity 2/2651 18/18639 0.111111111111111 0.78121463598642 0.748331783546764 0.999999999999821 GO:0015172 acidic amino acid transmembrane transporter activity 2/2651 18/18639 0.111111111111111 0.78121463598642 0.748331783546764 0.999999999999821 GO:0017075 syntaxin-1 binding 2/2651 18/18639 0.111111111111111 0.78121463598642 0.748331783546764 0.999999999999821 GO:0022851 GABA-gated chloride ion channel activity 2/2651 18/18639 0.111111111111111 0.78121463598642 0.748331783546764 0.999999999999821 GO:0005272 sodium channel activity 6/2651 51/18639 0.117647058823529 0.827168438103269 0.75131483575667 0.999999999999821 GO:0001671 ATPase activator activity 3/2651 27/18639 0.111111111111111 0.78121463598642 0.759884235542327 0.999999999999821 GO:0005104 fibroblast growth factor receptor binding 3/2651 27/18639 0.111111111111111 0.78121463598642 0.759884235542327 0.999999999999821 GO:0005385 zinc ion transmembrane transporter activity 3/2651 27/18639 0.111111111111111 0.78121463598642 0.759884235542327 0.999999999999821 GO:0005254 chloride channel activity 10/2651 83/18639 0.120481927710843 0.847100207696118 0.760473895251151 0.999999999999821 GO:0001046 core promoter sequence-specific DNA binding 5/2651 44/18639 0.113636363636364 0.798969514077021 0.769397725961733 0.999999999999821 GO:0016298 lipase activity 16/2651 130/18639 0.123076923076923 0.865345442938804 0.770462947899095 0.999999999999821 GO:0004190 aspartic-type endopeptidase activity 4/2651 36/18639 0.111111111111111 0.78121463598642 0.773264941148558 0.999999999999821 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 2/2651 19/18639 0.105263157894737 0.740098076197661 0.775166007997463 0.999999999999821 GO:0004890 GABA-A receptor activity 2/2651 19/18639 0.105263157894737 0.740098076197661 0.775166007997463 0.999999999999821 GO:0022821 solute:potassium antiporter activity 2/2651 19/18639 0.105263157894737 0.740098076197661 0.775166007997463 0.999999999999821 GO:0043395 heparan sulfate proteoglycan binding 2/2651 19/18639 0.105263157894737 0.740098076197661 0.775166007997463 0.999999999999821 GO:0052689 carboxylic ester hydrolase activity 11/2651 92/18639 0.119565217391304 0.840654880028865 0.77610801443182 0.999999999999821 GO:0051019 mitogen-activated protein kinase binding 3/2651 28/18639 0.107142857142857 0.753314113272619 0.78169765173618 0.999999999999821 GO:0051537 2 iron, 2 sulfur cluster binding 3/2651 28/18639 0.107142857142857 0.753314113272619 0.78169765173618 0.999999999999821 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 3/2651 28/18639 0.107142857142857 0.753314113272619 0.78169765173618 0.999999999999821 GO:0141052 histone H3 demethylase activity 3/2651 28/18639 0.107142857142857 0.753314113272619 0.78169765173618 0.999999999999821 GO:0140296 general transcription initiation factor binding 6/2651 53/18639 0.113207547169811 0.795954534778617 0.783975897027226 0.999999999999821 GO:0000182 rDNA binding 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0001164 RNA polymerase I core promoter sequence-specific DNA binding 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0004445 inositol-polyphosphate 5-phosphatase activity 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0015187 glycine transmembrane transporter activity 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0015924 mannosyl-oligosaccharide mannosidase activity 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0019531 oxalate transmembrane transporter activity 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0031078 histone H3K14 deacetylase activity, hydrolytic mechanism 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0031956 medium-chain fatty acid-CoA ligase activity 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0031996 thioesterase binding 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0032052 bile acid binding 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0034739 histone H4K16 deacetylase activity, hydrolytic mechanism 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0035256 G protein-coupled glutamate receptor binding 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0042975 peroxisome proliferator activated receptor binding 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0043208 glycosphingolipid binding 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0051378 serotonin binding 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0051864 histone H3K36 demethylase activity 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0070739 protein-glutamic acid ligase activity 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0070740 tubulin-glutamic acid ligase activity 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0099122 RNA polymerase II C-terminal domain binding 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0140999 histone H3K4 trimethyltransferase activity 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0180032 histone H4K5 deacetylase activity, hydrolytic mechanism 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0180033 histone H4K8 deacetylase activity, hydrolytic mechanism 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:1990162 histone H3K4 deacetylase activity, hydrolytic mechanism 1/2651 10/18639 0.1 0.703093172387778 0.784453292916009 0.999999999999821 GO:0008083 growth factor activity 20/2651 162/18639 0.123456790123457 0.868016262207133 0.785383213978563 0.999999999999821 GO:0019213 deacetylase activity 4/2651 37/18639 0.108108108108108 0.760100726905706 0.791761877135 0.999999999999821 GO:0023023 MHC protein complex binding 4/2651 37/18639 0.108108108108108 0.760100726905706 0.791761877135 0.999999999999821 GO:0070001 aspartic-type peptidase activity 4/2651 37/18639 0.108108108108108 0.760100726905706 0.791761877135 0.999999999999821 GO:0017069 snRNA binding 6/2651 54/18639 0.111111111111111 0.78121463598642 0.799036243391197 0.999999999999821 GO:0001614 purinergic nucleotide receptor activity 2/2651 20/18639 0.1 0.703093172387778 0.799461325384203 0.999999999999821 GO:0016004 phospholipase activator activity 2/2651 20/18639 0.1 0.703093172387778 0.799461325384203 0.999999999999821 GO:0016502 nucleotide receptor activity 2/2651 20/18639 0.1 0.703093172387778 0.799461325384203 0.999999999999821 GO:0016505 peptidase activator activity involved in apoptotic process 2/2651 20/18639 0.1 0.703093172387778 0.799461325384203 0.999999999999821 GO:0042288 MHC class I protein binding 2/2651 20/18639 0.1 0.703093172387778 0.799461325384203 0.999999999999821 GO:0061608 nuclear import signal receptor activity 2/2651 20/18639 0.1 0.703093172387778 0.799461325384203 0.999999999999821 GO:0035250 UDP-galactosyltransferase activity 3/2651 29/18639 0.103448275862069 0.727337764539081 0.801846636736095 0.999999999999821 GO:0004842 ubiquitin-protein transferase activity 58/2651 449/18639 0.129175946547884 0.90822726054546 0.80683671517764 0.999999999999821 GO:0000099 sulfur amino acid transmembrane transporter activity 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 0.999999999999821 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 0.999999999999821 GO:0001163 RNA polymerase I transcription regulatory region sequence-specific DNA binding 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 0.999999999999821 GO:0003953 NAD+ nucleosidase activity 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 0.999999999999821 GO:0008199 ferric iron binding 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 0.999999999999821 GO:0016176 superoxide-generating NADPH oxidase activator activity 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 0.999999999999821 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 0.999999999999821 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 0.999999999999821 GO:0032129 histone H3K9 deacetylase activity, hydrolytic mechanism 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 0.999999999999821 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 0.999999999999821 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 0.999999999999821 GO:0140537 transcription regulator activator activity 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 0.999999999999821 GO:0180030 inositol phosphate kinase activity 1/2651 11/18639 0.0909090909090909 0.639175611261617 0.815126668861023 0.999999999999821 GO:0030246 carbohydrate binding 35/2651 280/18639 0.125 0.878866465484723 0.819909770510799 0.999999999999821 GO:0032452 histone demethylase activity 3/2651 30/18639 0.1 0.703093172387778 0.820408789418824 0.999999999999821 GO:0033612 receptor serine/threonine kinase binding 3/2651 30/18639 0.1 0.703093172387778 0.820408789418824 0.999999999999821 GO:0035925 mRNA 3'-UTR AU-rich region binding 3/2651 30/18639 0.1 0.703093172387778 0.820408789418824 0.999999999999821 GO:0051721 protein phosphatase 2A binding 3/2651 30/18639 0.1 0.703093172387778 0.820408789418824 0.999999999999821 GO:0000049 tRNA binding 9/2651 80/18639 0.1125 0.790979818936251 0.820886954445711 0.999999999999821 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2/2651 21/18639 0.0952380952380952 0.669612545131217 0.821396825264985 0.999999999999821 GO:0005248 voltage-gated sodium channel activity 2/2651 21/18639 0.0952380952380952 0.669612545131217 0.821396825264985 0.999999999999821 GO:0036122 BMP binding 2/2651 21/18639 0.0952380952380952 0.669612545131217 0.821396825264985 0.999999999999821 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2/2651 21/18639 0.0952380952380952 0.669612545131217 0.821396825264985 0.999999999999821 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 6/2651 56/18639 0.107142857142857 0.753314113272619 0.826701178852402 0.999999999999821 GO:0016411 acylglycerol O-acyltransferase activity 3/2651 31/18639 0.0967741935483871 0.680412747472043 0.837466809672217 0.999999999999821 GO:0047499 calcium-independent phospholipase A2 activity 3/2651 31/18639 0.0967741935483871 0.680412747472043 0.837466809672217 0.999999999999821 GO:0140457 protein demethylase activity 3/2651 31/18639 0.0967741935483871 0.680412747472043 0.837466809672217 0.999999999999821 GO:0030331 nuclear estrogen receptor binding 4/2651 40/18639 0.1 0.703093172387778 0.840042004158798 0.999999999999821 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 4/2651 40/18639 0.1 0.703093172387778 0.840042004158798 0.999999999999821 GO:0004866 endopeptidase inhibitor activity 19/2651 161/18639 0.118012422360248 0.829737284184334 0.840781849927647 0.999999999999821 GO:0004407 histone deacetylase activity 2/2651 22/18639 0.0909090909090909 0.639175611261617 0.841152029770087 0.999999999999821 GO:0033558 protein lysine deacetylase activity 2/2651 22/18639 0.0909090909090909 0.639175611261617 0.841152029770087 0.999999999999821 GO:0070034 telomerase RNA binding 2/2651 22/18639 0.0909090909090909 0.639175611261617 0.841152029770087 0.999999999999821 GO:0003720 telomerase activity 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 0.999999999999821 GO:0004000 adenosine deaminase activity 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 0.999999999999821 GO:0004126 cytidine deaminase activity 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 0.999999999999821 GO:0004859 phospholipase inhibitor activity 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 0.999999999999821 GO:0005078 MAP-kinase scaffold activity 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 0.999999999999821 GO:0008499 N-acetyl-beta-D-glucosaminide beta-(1,3)-galactosyltransferase activity 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 0.999999999999821 GO:0015132 prostaglandin transmembrane transporter activity 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 0.999999999999821 GO:0015269 calcium-activated potassium channel activity 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 0.999999999999821 GO:0015368 calcium:monoatomic cation antiporter activity 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 0.999999999999821 GO:0016273 arginine N-methyltransferase activity 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 0.999999999999821 GO:0016274 protein-arginine N-methyltransferase activity 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 0.999999999999821 GO:0016840 carbon-nitrogen lyase activity 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 0.999999999999821 GO:0034452 dynactin binding 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 0.999999999999821 GO:0035259 nuclear glucocorticoid receptor binding 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 0.999999999999821 GO:0035497 cAMP response element binding 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 0.999999999999821 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 0.999999999999821 GO:0070410 co-SMAD binding 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 0.999999999999821 GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 0.999999999999821 GO:0140829 bicarbonate:monoatomic anion antiporter activity 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 0.999999999999821 GO:0140900 chloride:bicarbonate antiporter activity 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 0.999999999999821 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 0.999999999999821 GO:1990247 N6-methyladenosine-containing RNA reader activity 1/2651 12/18639 0.0833333333333333 0.585910976989815 0.841436482091076 0.999999999999821 GO:0030414 peptidase inhibitor activity 20/2651 169/18639 0.118343195266272 0.832062925902696 0.84251609444355 0.999999999999821 GO:0070851 growth factor receptor binding 16/2651 139/18639 0.115107913669065 0.809315881885212 0.851904011748123 0.999999999999821 GO:0015106 bicarbonate transmembrane transporter activity 3/2651 32/18639 0.09375 0.659149849113542 0.85310640499008 0.999999999999821 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 3/2651 32/18639 0.09375 0.659149849113542 0.85310640499008 0.999999999999821 GO:0047498 calcium-dependent phospholipase A2 activity 3/2651 32/18639 0.09375 0.659149849113542 0.85310640499008 0.999999999999821 GO:0070717 poly-purine tract binding 3/2651 32/18639 0.09375 0.659149849113542 0.85310640499008 0.999999999999821 GO:0001530 lipopolysaccharide binding 4/2651 41/18639 0.0975609756097561 0.685944558427101 0.853893094355398 0.999999999999821 GO:0140318 protein transporter activity 4/2651 41/18639 0.0975609756097561 0.685944558427101 0.853893094355398 0.999999999999821 GO:0004022 alcohol dehydrogenase (NAD+) activity 2/2651 23/18639 0.0869565217391304 0.61138536729372 0.8589031490027 0.999999999999821 GO:0005283 amino acid:sodium symporter activity 2/2651 23/18639 0.0869565217391304 0.61138536729372 0.8589031490027 0.999999999999821 GO:0016493 C-C chemokine receptor activity 2/2651 23/18639 0.0869565217391304 0.61138536729372 0.8589031490027 0.999999999999821 GO:0016917 GABA receptor activity 2/2651 23/18639 0.0869565217391304 0.61138536729372 0.8589031490027 0.999999999999821 GO:0043274 phospholipase binding 2/2651 23/18639 0.0869565217391304 0.61138536729372 0.8589031490027 0.999999999999821 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 2/2651 23/18639 0.0869565217391304 0.61138536729372 0.8589031490027 0.999999999999821 GO:0036002 pre-mRNA binding 6/2651 59/18639 0.101694915254237 0.71501000581808 0.862398952356686 0.999999999999821 GO:0002161 aminoacyl-tRNA editing activity 1/2651 13/18639 0.0769230769230769 0.540840901836752 0.864003287587214 0.999999999999821 GO:0004465 lipoprotein lipase activity 1/2651 13/18639 0.0769230769230769 0.540840901836752 0.864003287587214 0.999999999999821 GO:0004535 poly(A)-specific ribonuclease activity 1/2651 13/18639 0.0769230769230769 0.540840901836752 0.864003287587214 0.999999999999821 GO:0008035 high-density lipoprotein particle binding 1/2651 13/18639 0.0769230769230769 0.540840901836752 0.864003287587214 0.999999999999821 GO:0008253 5'-nucleotidase activity 1/2651 13/18639 0.0769230769230769 0.540840901836752 0.864003287587214 0.999999999999821 GO:0015651 quaternary ammonium group transmembrane transporter activity 1/2651 13/18639 0.0769230769230769 0.540840901836752 0.864003287587214 0.999999999999821 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 1/2651 13/18639 0.0769230769230769 0.540840901836752 0.864003287587214 0.999999999999821 GO:0030955 potassium ion binding 1/2651 13/18639 0.0769230769230769 0.540840901836752 0.864003287587214 0.999999999999821 GO:0031432 titin binding 1/2651 13/18639 0.0769230769230769 0.540840901836752 0.864003287587214 0.999999999999821 GO:0071714 icosanoid transmembrane transporter activity 1/2651 13/18639 0.0769230769230769 0.540840901836752 0.864003287587214 0.999999999999821 GO:0140410 monoatomic cation:bicarbonate symporter activity 1/2651 13/18639 0.0769230769230769 0.540840901836752 0.864003287587214 0.999999999999821 GO:0004620 phospholipase activity 12/2651 109/18639 0.110091743119266 0.774047529234251 0.866595923905665 0.999999999999821 GO:0071889 14-3-3 protein binding 3/2651 33/18639 0.0909090909090909 0.639175611261617 0.867414557215386 0.999999999999821 GO:0061659 ubiquitin-like protein ligase activity 46/2651 372/18639 0.123655913978495 0.8694162884365 0.867730182216611 0.999999999999821 GO:0004222 metalloendopeptidase activity 12/2651 110/18639 0.109090909090909 0.76701073351394 0.874358668798433 0.999999999999821 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 2/2651 24/18639 0.0833333333333333 0.585910976989815 0.874820392180866 0.999999999999821 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 2/2651 24/18639 0.0833333333333333 0.585910976989815 0.874820392180866 0.999999999999821 GO:0019957 C-C chemokine binding 2/2651 24/18639 0.0833333333333333 0.585910976989815 0.874820392180866 0.999999999999821 GO:0030552 cAMP binding 2/2651 24/18639 0.0833333333333333 0.585910976989815 0.874820392180866 0.999999999999821 GO:0035035 histone acetyltransferase binding 2/2651 24/18639 0.0833333333333333 0.585910976989815 0.874820392180866 0.999999999999821 GO:0060229 lipase activator activity 2/2651 24/18639 0.0833333333333333 0.585910976989815 0.874820392180866 0.999999999999821 GO:0070300 phosphatidic acid binding 2/2651 24/18639 0.0833333333333333 0.585910976989815 0.874820392180866 0.999999999999821 GO:0015171 amino acid transmembrane transporter activity 11/2651 102/18639 0.107843137254902 0.758237734927996 0.875436427683312 0.999999999999821 GO:0098960 postsynaptic neurotransmitter receptor activity 7/2651 69/18639 0.101449275362319 0.71328292850934 0.877402840887372 0.999999999999821 GO:0004175 endopeptidase activity 50/2651 405/18639 0.123456790123457 0.868016262207133 0.87944012960768 0.999999999999821 GO:0008175 tRNA methyltransferase activity 3/2651 34/18639 0.0882352941176471 0.620376328577451 0.880478108126778 0.999999999999821 GO:0015020 glucuronosyltransferase activity 3/2651 34/18639 0.0882352941176471 0.620376328577451 0.880478108126778 0.999999999999821 GO:0005313 L-glutamate transmembrane transporter activity 1/2651 14/18639 0.0714285714285714 0.502209408848413 0.883359417975182 0.999999999999821 GO:0005344 oxygen carrier activity 1/2651 14/18639 0.0714285714285714 0.502209408848413 0.883359417975182 0.999999999999821 GO:0008191 metalloendopeptidase inhibitor activity 1/2651 14/18639 0.0714285714285714 0.502209408848413 0.883359417975182 0.999999999999821 GO:0008392 arachidonate epoxygenase activity 1/2651 14/18639 0.0714285714285714 0.502209408848413 0.883359417975182 0.999999999999821 GO:0015386 potassium:proton antiporter activity 1/2651 14/18639 0.0714285714285714 0.502209408848413 0.883359417975182 0.999999999999821 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/2651 14/18639 0.0714285714285714 0.502209408848413 0.883359417975182 0.999999999999821 GO:0031404 chloride ion binding 1/2651 14/18639 0.0714285714285714 0.502209408848413 0.883359417975182 0.999999999999821 GO:0032454 histone H3K9 demethylase activity 1/2651 14/18639 0.0714285714285714 0.502209408848413 0.883359417975182 0.999999999999821 GO:0034236 protein kinase A catalytic subunit binding 1/2651 14/18639 0.0714285714285714 0.502209408848413 0.883359417975182 0.999999999999821 GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 1/2651 14/18639 0.0714285714285714 0.502209408848413 0.883359417975182 0.999999999999821 GO:0043176 amine binding 1/2651 14/18639 0.0714285714285714 0.502209408848413 0.883359417975182 0.999999999999821 GO:0046030 inositol trisphosphate phosphatase activity 1/2651 14/18639 0.0714285714285714 0.502209408848413 0.883359417975182 0.999999999999821 GO:0070742 C2H2 zinc finger domain binding 1/2651 14/18639 0.0714285714285714 0.502209408848413 0.883359417975182 0.999999999999821 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 1/2651 14/18639 0.0714285714285714 0.502209408848413 0.883359417975182 0.999999999999821 GO:0015079 potassium ion transmembrane transporter activity 18/2651 160/18639 0.1125 0.790979818936251 0.886662641284073 0.999999999999821 GO:0008139 nuclear localization sequence binding 2/2651 25/18639 0.08 0.562474537910223 0.889066110126847 0.999999999999821 GO:0042974 nuclear retinoic acid receptor binding 2/2651 25/18639 0.08 0.562474537910223 0.889066110126847 0.999999999999821 GO:1904315 transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential 5/2651 53/18639 0.0943396226415094 0.663295445648847 0.889762592991238 0.999999999999821 GO:0033293 monocarboxylic acid binding 8/2651 79/18639 0.10126582278481 0.711993085962307 0.89050297556913 0.999999999999821 GO:0000175 3'-5'-RNA exonuclease activity 3/2651 35/18639 0.0857142857142857 0.602651290618096 0.892382624359586 0.999999999999821 GO:0004623 phospholipase A2 activity 3/2651 35/18639 0.0857142857142857 0.602651290618096 0.892382624359586 0.999999999999821 GO:0005154 epidermal growth factor receptor binding 3/2651 35/18639 0.0857142857142857 0.602651290618096 0.892382624359586 0.999999999999821 GO:0016229 steroid dehydrogenase activity 3/2651 35/18639 0.0857142857142857 0.602651290618096 0.892382624359586 0.999999999999821 GO:0004540 RNA nuclease activity 13/2651 121/18639 0.107438016528926 0.755389358763729 0.89428227142288 0.999999999999821 GO:0004089 carbonate dehydratase activity 1/2651 15/18639 0.0666666666666667 0.468728781591852 0.899961521757614 0.999999999999821 GO:0004559 alpha-mannosidase activity 1/2651 15/18639 0.0666666666666667 0.468728781591852 0.899961521757614 0.999999999999821 GO:0008252 nucleotidase activity 1/2651 15/18639 0.0666666666666667 0.468728781591852 0.899961521757614 0.999999999999821 GO:0010181 FMN binding 1/2651 15/18639 0.0666666666666667 0.468728781591852 0.899961521757614 0.999999999999821 GO:0015250 water channel activity 1/2651 15/18639 0.0666666666666667 0.468728781591852 0.899961521757614 0.999999999999821 GO:0030553 cGMP binding 1/2651 15/18639 0.0666666666666667 0.468728781591852 0.899961521757614 0.999999999999821 GO:0031005 filamin binding 1/2651 15/18639 0.0666666666666667 0.468728781591852 0.899961521757614 0.999999999999821 GO:0031386 protein tag activity 1/2651 15/18639 0.0666666666666667 0.468728781591852 0.899961521757614 0.999999999999821 GO:0034483 heparan sulfate sulfotransferase activity 1/2651 15/18639 0.0666666666666667 0.468728781591852 0.899961521757614 0.999999999999821 GO:0042809 nuclear vitamin D receptor binding 1/2651 15/18639 0.0666666666666667 0.468728781591852 0.899961521757614 0.999999999999821 GO:0050700 CARD domain binding 1/2651 15/18639 0.0666666666666667 0.468728781591852 0.899961521757614 0.999999999999821 GO:0141047 molecular tag activity 1/2651 15/18639 0.0666666666666667 0.468728781591852 0.899961521757614 0.999999999999821 GO:0022824 transmitter-gated monoatomic ion channel activity 6/2651 63/18639 0.0952380952380952 0.669612545131217 0.900306720304212 0.999999999999821 GO:0022835 transmitter-gated channel activity 6/2651 63/18639 0.0952380952380952 0.669612545131217 0.900306720304212 0.999999999999821 GO:0004112 cyclic-nucleotide phosphodiesterase activity 2/2651 26/18639 0.0769230769230769 0.540840901836752 0.901793587149495 0.999999999999821 GO:0004435 phosphatidylinositol phospholipase C activity 2/2651 26/18639 0.0769230769230769 0.540840901836752 0.901793587149495 0.999999999999821 GO:0005227 calcium-activated cation channel activity 2/2651 26/18639 0.0769230769230769 0.540840901836752 0.901793587149495 0.999999999999821 GO:0008143 poly(A) binding 2/2651 26/18639 0.0769230769230769 0.540840901836752 0.901793587149495 0.999999999999821 GO:0008157 protein phosphatase 1 binding 2/2651 26/18639 0.0769230769230769 0.540840901836752 0.901793587149495 0.999999999999821 GO:0008198 ferrous iron binding 2/2651 26/18639 0.0769230769230769 0.540840901836752 0.901793587149495 0.999999999999821 GO:0030247 polysaccharide binding 2/2651 26/18639 0.0769230769230769 0.540840901836752 0.901793587149495 0.999999999999821 GO:0070412 R-SMAD binding 2/2651 26/18639 0.0769230769230769 0.540840901836752 0.901793587149495 0.999999999999821 GO:0120014 phospholipid transfer activity 2/2651 26/18639 0.0769230769230769 0.540840901836752 0.901793587149495 0.999999999999821 GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity 3/2651 36/18639 0.0833333333333333 0.585910976989815 0.903211504651497 0.999999999999821 GO:0004180 carboxypeptidase activity 4/2651 46/18639 0.0869565217391304 0.61138536729372 0.90874268847816 0.999999999999821 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 20/2651 181/18639 0.110497237569061 0.776898533025169 0.912844202611103 0.999999999999821 GO:0030280 structural constituent of skin epidermis 3/2651 37/18639 0.0810810810810811 0.57007554517928 0.913045295314718 0.999999999999821 GO:0030551 cyclic nucleotide binding 3/2651 37/18639 0.0810810810810811 0.57007554517928 0.913045295314718 0.999999999999821 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 2/2651 27/18639 0.0740740740740741 0.52080975732428 0.913146335278068 0.999999999999821 GO:0004708 MAP kinase kinase activity 1/2651 16/18639 0.0625 0.439433232742361 0.91420132018011 0.999999999999821 GO:0008391 arachidonate monooxygenase activity 1/2651 16/18639 0.0625 0.439433232742361 0.91420132018011 0.999999999999821 GO:0015378 sodium:chloride symporter activity 1/2651 16/18639 0.0625 0.439433232742361 0.91420132018011 0.999999999999821 GO:0015385 sodium:proton antiporter activity 1/2651 16/18639 0.0625 0.439433232742361 0.91420132018011 0.999999999999821 GO:0015923 mannosidase activity 1/2651 16/18639 0.0625 0.439433232742361 0.91420132018011 0.999999999999821 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/2651 16/18639 0.0625 0.439433232742361 0.91420132018011 0.999999999999821 GO:0055102 lipase inhibitor activity 1/2651 16/18639 0.0625 0.439433232742361 0.91420132018011 0.999999999999821 GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 1/2651 16/18639 0.0625 0.439433232742361 0.91420132018011 0.999999999999821 GO:0120013 lipid transfer activity 6/2651 65/18639 0.0923076923076923 0.649009082204103 0.915638362955002 0.999999999999821 GO:0005504 fatty acid binding 4/2651 47/18639 0.0851063829787234 0.598377167989599 0.917212440109905 0.999999999999821 GO:0099095 ligand-gated monoatomic anion channel activity 4/2651 47/18639 0.0851063829787234 0.598377167989599 0.917212440109905 0.999999999999821 GO:0016896 RNA exonuclease activity, producing 5'-phosphomonoesters 3/2651 38/18639 0.0789473684210526 0.555073557148246 0.921961182947257 0.999999999999821 GO:0005242 inward rectifier potassium channel activity 2/2651 28/18639 0.0714285714285714 0.502209408848413 0.923257772473598 0.999999999999821 GO:0004438 phosphatidylinositol-3-phosphate phosphatase activity 1/2651 17/18639 0.0588235294117647 0.413584219051634 0.926414835736278 0.999999999999821 GO:0008569 minus-end-directed microtubule motor activity 1/2651 17/18639 0.0588235294117647 0.413584219051634 0.926414835736278 0.999999999999821 GO:0015347 sodium-independent organic anion transmembrane transporter activity 1/2651 17/18639 0.0588235294117647 0.413584219051634 0.926414835736278 0.999999999999821 GO:0030548 acetylcholine receptor regulator activity 1/2651 17/18639 0.0588235294117647 0.413584219051634 0.926414835736278 0.999999999999821 GO:0036041 long-chain fatty acid binding 1/2651 17/18639 0.0588235294117647 0.413584219051634 0.926414835736278 0.999999999999821 GO:0048038 quinone binding 1/2651 17/18639 0.0588235294117647 0.413584219051634 0.926414835736278 0.999999999999821 GO:0051787 misfolded protein binding 1/2651 17/18639 0.0588235294117647 0.413584219051634 0.926414835736278 0.999999999999821 GO:0070492 oligosaccharide binding 1/2651 17/18639 0.0588235294117647 0.413584219051634 0.926414835736278 0.999999999999821 GO:0004181 metallocarboxypeptidase activity 2/2651 29/18639 0.0689655172413793 0.484891843026054 0.932251189935636 0.999999999999821 GO:0005416 amino acid:monoatomic cation symporter activity 2/2651 29/18639 0.0689655172413793 0.484891843026054 0.932251189935636 0.999999999999821 GO:0061630 ubiquitin protein ligase activity 41/2651 353/18639 0.11614730878187 0.816623797957476 0.935481352342855 0.999999999999821 GO:0070888 E-box binding 5/2651 59/18639 0.0847457627118644 0.595841671515066 0.935829584579177 0.999999999999821 GO:0003746 translation elongation factor activity 1/2651 18/18639 0.0555555555555556 0.39060731799321 0.936890309394485 0.999999999999821 GO:0004970 glutamate-gated receptor activity 1/2651 18/18639 0.0555555555555556 0.39060731799321 0.936890309394485 0.999999999999821 GO:0005372 water transmembrane transporter activity 1/2651 18/18639 0.0555555555555556 0.39060731799321 0.936890309394485 0.999999999999821 GO:0015280 ligand-gated sodium channel activity 1/2651 18/18639 0.0555555555555556 0.39060731799321 0.936890309394485 0.999999999999821 GO:0015373 monoatomic anion:sodium symporter activity 1/2651 18/18639 0.0555555555555556 0.39060731799321 0.936890309394485 0.999999999999821 GO:0032393 MHC class I receptor activity 1/2651 18/18639 0.0555555555555556 0.39060731799321 0.936890309394485 0.999999999999821 GO:0052744 phosphatidylinositol monophosphate phosphatase activity 1/2651 18/18639 0.0555555555555556 0.39060731799321 0.936890309394485 0.999999999999821 GO:0099602 neurotransmitter receptor regulator activity 1/2651 18/18639 0.0555555555555556 0.39060731799321 0.936890309394485 0.999999999999821 GO:1990381 ubiquitin-specific protease binding 1/2651 18/18639 0.0555555555555556 0.39060731799321 0.936890309394485 0.999999999999821 GO:0004532 RNA exonuclease activity 3/2651 40/18639 0.075 0.527319879290834 0.937329174312331 0.999999999999821 GO:0032451 demethylase activity 3/2651 40/18639 0.075 0.527319879290834 0.937329174312331 0.999999999999821 GO:0050997 quaternary ammonium group binding 3/2651 40/18639 0.075 0.527319879290834 0.937329174312331 0.999999999999821 GO:0071855 neuropeptide receptor binding 3/2651 40/18639 0.075 0.527319879290834 0.937329174312331 0.999999999999821 GO:0001965 G-protein alpha-subunit binding 2/2651 30/18639 0.0666666666666667 0.468728781591852 0.940239932829694 0.999999999999821 GO:0022839 monoatomic ion-gated channel activity 2/2651 30/18639 0.0666666666666667 0.468728781591852 0.940239932829694 0.999999999999821 GO:0048019 receptor antagonist activity 2/2651 30/18639 0.0666666666666667 0.468728781591852 0.940239932829694 0.999999999999821 GO:0070566 adenylyltransferase activity 2/2651 30/18639 0.0666666666666667 0.468728781591852 0.940239932829694 0.999999999999821 GO:0004812 aminoacyl-tRNA ligase activity 3/2651 41/18639 0.0731707317073171 0.514458418820326 0.943916233256299 0.999999999999821 GO:0016875 ligase activity, forming carbon-oxygen bonds 3/2651 41/18639 0.0731707317073171 0.514458418820326 0.943916233256299 0.999999999999821 GO:0042287 MHC protein binding 3/2651 41/18639 0.0731707317073171 0.514458418820326 0.943916233256299 0.999999999999821 GO:0140828 metal cation:monoatomic cation antiporter activity 3/2651 41/18639 0.0731707317073171 0.514458418820326 0.943916233256299 0.999999999999821 GO:0003743 translation initiation factor activity 4/2651 51/18639 0.0784313725490196 0.551445625402179 0.944469928841444 0.999999999999821 GO:0046873 metal ion transmembrane transporter activity 53/2651 450/18639 0.117777777777778 0.828087514145605 0.944866707300526 0.999999999999821 GO:0005229 intracellularly calcium-gated chloride channel activity 1/2651 19/18639 0.0526315789473684 0.370049038098831 0.945874992805431 0.999999999999821 GO:0016918 retinal binding 1/2651 19/18639 0.0526315789473684 0.370049038098831 0.945874992805431 0.999999999999821 GO:0141147 intracellularly calcium-gated channel activity 1/2651 19/18639 0.0526315789473684 0.370049038098831 0.945874992805431 0.999999999999821 GO:0035198 miRNA binding 3/2651 42/18639 0.0714285714285714 0.502209408848413 0.949855122737672 0.999999999999821 GO:0001664 G protein-coupled receptor binding 33/2651 297/18639 0.111111111111111 0.78121463598642 0.952382626939218 0.999999999999821 GO:0001972 retinoic acid binding 1/2651 20/18639 0.05 0.351546586193889 0.953580975301285 0.999999999999821 GO:0004745 all-trans-retinol dehydrogenase (NAD+) activity 1/2651 20/18639 0.05 0.351546586193889 0.953580975301285 0.999999999999821 GO:0052745 inositol phosphate phosphatase activity 1/2651 20/18639 0.05 0.351546586193889 0.953580975301285 0.999999999999821 GO:0022884 macromolecule transmembrane transporter activity 2/2651 32/18639 0.0625 0.439433232742361 0.953609156389207 0.999999999999821 GO:0120015 sterol transfer activity 2/2651 32/18639 0.0625 0.439433232742361 0.953609156389207 0.999999999999821 GO:0005245 voltage-gated calcium channel activity 3/2651 43/18639 0.0697674418604651 0.490530120270543 0.955203045292672 0.999999999999821 GO:0005126 cytokine receptor binding 30/2651 275/18639 0.109090909090909 0.76701073351394 0.95672641280572 0.999999999999821 GO:0008236 serine-type peptidase activity 20/2651 194/18639 0.103092783505155 0.724838322049256 0.957641063529105 0.999999999999821 GO:0005230 extracellular ligand-gated monoatomic ion channel activity 6/2651 73/18639 0.0821917808219178 0.577884799222831 0.95822799961857 0.999999999999821 GO:0019239 deaminase activity 2/2651 33/18639 0.0606060606060606 0.426117074174411 0.959170098271388 0.999999999999821 GO:0042923 neuropeptide binding 2/2651 33/18639 0.0606060606060606 0.426117074174411 0.959170098271388 0.999999999999821 GO:0015125 bile acid transmembrane transporter activity 1/2651 21/18639 0.0476190476190476 0.334806272565609 0.9601901828031 0.999999999999821 GO:0019200 carbohydrate kinase activity 1/2651 21/18639 0.0476190476190476 0.334806272565609 0.9601901828031 0.999999999999821 GO:0051428 peptide hormone receptor binding 1/2651 21/18639 0.0476190476190476 0.334806272565609 0.9601901828031 0.999999999999821 GO:0008135 translation factor activity, RNA binding 7/2651 83/18639 0.0843373493975904 0.592970145387283 0.960785450098562 0.999999999999821 GO:0180051 translation factor activity 7/2651 84/18639 0.0833333333333333 0.585910976989815 0.964063903036188 0.999999999999821 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 2/2651 34/18639 0.0588235294117647 0.413584219051634 0.964088347655427 0.999999999999821 GO:0052866 phosphatidylinositol phosphate phosphatase activity 2/2651 34/18639 0.0588235294117647 0.413584219051634 0.964088347655427 0.999999999999821 GO:0008649 rRNA methyltransferase activity 1/2651 22/18639 0.0454545454545455 0.319587805630808 0.965858666280862 0.999999999999821 GO:0008970 phospholipase A1 activity 1/2651 22/18639 0.0454545454545455 0.319587805630808 0.965858666280862 0.999999999999821 GO:0033691 sialic acid binding 1/2651 22/18639 0.0454545454545455 0.319587805630808 0.965858666280862 0.999999999999821 GO:0017171 serine hydrolase activity 20/2651 198/18639 0.101010101010101 0.710195123624018 0.96660219065573 0.999999999999821 GO:0140375 immune receptor activity 15/2651 156/18639 0.0961538461538462 0.676051127295941 0.967156967366153 0.999999999999821 GO:0042277 peptide binding 26/2651 249/18639 0.104417670682731 0.734153513336636 0.969119090865872 0.999999999999821 GO:0008173 RNA methyltransferase activity 5/2651 67/18639 0.0746268656716418 0.524696397304312 0.970306089373649 0.999999999999821 GO:0140102 catalytic activity, acting on a rRNA 1/2651 23/18639 0.0434782608695652 0.30569268364686 0.970720280702597 0.999999999999821 GO:0008237 metallopeptidase activity 18/2651 184/18639 0.0978260869565217 0.687808538205435 0.971991726564085 0.999999999999821 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/2651 36/18639 0.0555555555555556 0.39060731799321 0.972270775209402 0.999999999999821 GO:0005484 SNAP receptor activity 2/2651 36/18639 0.0555555555555556 0.39060731799321 0.972270775209402 0.999999999999821 GO:0061980 regulatory RNA binding 4/2651 58/18639 0.0689655172413793 0.484891843026054 0.973289443000068 0.999999999999821 GO:0005267 potassium channel activity 11/2651 124/18639 0.0887096774193548 0.623711685182706 0.973424308726525 0.999999999999821 GO:0030594 neurotransmitter receptor activity 8/2651 97/18639 0.0824742268041237 0.579870657639405 0.97400281875345 0.999999999999821 GO:0022836 gated channel activity 34/2651 318/18639 0.106918238993711 0.751734838402027 0.974749760909808 0.999999999999821 GO:0008188 neuropeptide receptor activity 3/2651 48/18639 0.0625 0.439433232742361 0.97480519643106 0.999999999999821 GO:0005249 voltage-gated potassium channel activity 8/2651 98/18639 0.0816326530612245 0.573953610112472 0.976157906388633 0.999999999999821 GO:0046906 tetrapyrrole binding 14/2651 152/18639 0.0921052631578947 0.647585816672954 0.976231120070931 0.999999999999821 GO:0022834 ligand-gated channel activity 18/2651 188/18639 0.0957446808510638 0.673174313988298 0.978400555045584 0.999999999999821 GO:0120020 cholesterol transfer activity 1/2651 25/18639 0.04 0.281237268955111 0.978465829862535 0.999999999999821 GO:0005501 retinoid binding 2/2651 38/18639 0.0526315789473684 0.370049038098831 0.978638083090628 0.999999999999821 GO:0019840 isoprenoid binding 2/2651 38/18639 0.0526315789473684 0.370049038098831 0.978638083090628 0.999999999999821 GO:0099094 ligand-gated monoatomic cation channel activity 12/2651 136/18639 0.0882352941176471 0.620376328577451 0.978999334075979 0.999999999999821 GO:0005506 iron ion binding 14/2651 154/18639 0.0909090909090909 0.639175611261617 0.979418962108566 0.999999999999821 GO:0019905 syntaxin binding 4/2651 61/18639 0.0655737704918033 0.4610447032051 0.980696972868342 0.999999999999821 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 7/2651 91/18639 0.0769230769230769 0.540840901836752 0.980863037688098 0.999999999999821 GO:0008066 glutamate receptor activity 1/2651 26/18639 0.0384615384615385 0.270420450918376 0.981532719571056 0.999999999999821 GO:0051139 metal cation:proton antiporter activity 1/2651 26/18639 0.0384615384615385 0.270420450918376 0.981532719571056 0.999999999999821 GO:0015085 calcium ion transmembrane transporter activity 13/2651 147/18639 0.0884353741496599 0.621783077621845 0.982057050161551 0.999999999999821 GO:0004683 calcium/calmodulin-dependent protein kinase activity 1/2651 27/18639 0.037037037037037 0.26040487866214 0.984162965120786 0.999999999999821 GO:0008320 protein transmembrane transporter activity 1/2651 27/18639 0.037037037037037 0.26040487866214 0.984162965120786 0.999999999999821 GO:0015252 proton channel activity 1/2651 27/18639 0.037037037037037 0.26040487866214 0.984162965120786 0.999999999999821 GO:0005262 calcium channel activity 11/2651 131/18639 0.083969465648855 0.5903835798676 0.984716166585898 0.999999999999821 GO:0004252 serine-type endopeptidase activity 16/2651 176/18639 0.0909090909090909 0.639175611261617 0.985016144687686 0.999999999999821 GO:0015276 ligand-gated monoatomic ion channel activity 17/2651 186/18639 0.0913978494623656 0.642612039279152 0.98626528616213 0.999999999999821 GO:0051879 Hsp90 protein binding 2/2651 42/18639 0.0476190476190476 0.334806272565609 0.987399598296499 0.999999999999821 GO:0031210 phosphatidylcholine binding 1/2651 30/18639 0.0333333333333333 0.234364390795926 0.990012347893779 0.999999999999821 GO:0030547 signaling receptor inhibitor activity 2/2651 44/18639 0.0454545454545455 0.319587805630808 0.990349066199255 0.999999999999821 GO:0031369 translation initiation factor binding 1/2651 32/18639 0.03125 0.219716616371181 0.992655362276663 0.999999999999821 GO:0005179 hormone activity 10/2651 132/18639 0.0757575757575758 0.532646342718014 0.993651731068707 0.999999999999821 GO:0020037 heme binding 11/2651 142/18639 0.0774647887323944 0.544649640582082 0.993907778336265 0.999999999999821 GO:0140098 catalytic activity, acting on RNA 39/2651 387/18639 0.10077519379845 0.708543507057451 0.99430139838397 0.999999999999821 GO:0005244 voltage-gated monoatomic ion channel activity 14/2651 173/18639 0.0809248554913295 0.568977133724214 0.995222808347543 0.999999999999821 GO:0022832 voltage-gated channel activity 14/2651 175/18639 0.08 0.562474537910223 0.995940276954717 0.999999999999821 GO:0005048 signal sequence binding 2/2651 51/18639 0.0392156862745098 0.275722812701089 0.996250656434376 0.999999999999821 GO:0140101 catalytic activity, acting on a tRNA 10/2651 139/18639 0.0719424460431655 0.505822426178258 0.996623996551566 0.999999999999821 GO:0005216 monoatomic ion channel activity 45/2651 448/18639 0.100446428571429 0.706231981193081 0.99692501953887 0.999999999999821 GO:0016251 RNA polymerase II general transcription initiation factor activity 2/2651 53/18639 0.0377358490566038 0.265318178259539 0.997146866077846 0.999999999999821 GO:0022843 voltage-gated monoatomic cation channel activity 10/2651 143/18639 0.0699300699300699 0.49167354712432 0.997668941610124 0.999999999999821 GO:0000149 SNARE binding 6/2651 106/18639 0.0566037735849057 0.397977267389308 0.998518561026738 0.999999999999821 GO:0001653 peptide receptor activity 8/2651 128/18639 0.0625 0.439433232742361 0.99861401427555 0.999999999999821 GO:0042605 peptide antigen binding 1/2651 45/18639 0.0222222222222222 0.156242927197284 0.999004852472997 0.999999999999821 GO:0008528 G protein-coupled peptide receptor activity 7/2651 122/18639 0.0573770491803279 0.403414115304463 0.999146296923353 0.999999999999821 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 1/2651 46/18639 0.0217391304347826 0.15284634182343 0.999146733514951 0.999999999999821 GO:0005261 monoatomic cation channel activity 30/2651 341/18639 0.0879765395894428 0.618557043156403 0.999177719818283 0.999999999999821 GO:0004497 monooxygenase activity 5/2651 106/18639 0.0471698113207547 0.331647722824424 0.999595154893076 0.999999999999821 GO:0140223 general transcription initiation factor activity 2/2651 68/18639 0.0294117647058824 0.206792109525817 0.999644250433733 0.999999999999821 GO:0005125 cytokine activity 14/2651 234/18639 0.0598290598290598 0.420654034761919 0.999981731450126 0.999999999999821 GO:0042379 chemokine receptor binding 1/2651 72/18639 0.0138888888888889 0.0976518294983025 0.999984409939755 0.999999999999821 GO:0003730 mRNA 3'-UTR binding 16/2651 262/18639 0.0610687022900763 0.429369876267345 0.999990927565341 0.999999999999821 GO:0030527 structural constituent of chromatin 2/2651 98/18639 0.0204081632653061 0.143488402528118 0.999995088144659 0.999999999999821 GO:0003823 antigen binding 2/2651 174/18639 0.0114942528735632 0.080815307171009 0.999999999932759 0.999999999999821 GO:0045182 translation regulator activity 11/2651 356/18639 0.0308988764044944 0.217247890344538 0.999999999999802 0.999999999999821 GO:0030371 translation repressor activity 9/2651 329/18639 0.027355623100304 0.192335518282371 0.999999999999821 0.999999999999821