category subcategory ID Description GeneRatio BgRatio FoldEnrichment geneName zScore Organismal Systems Digestive system hsa04974 Protein digestion and absorption 5/14 103/9376 32.5104022191401 COL15A1/COL4A2/COL4A1/COL3A1/PRCP 12.4344839737914 Human Diseases Endocrine and metabolic disease hsa04933 AGE-RAGE signaling pathway in diabetic complications 4/14 101/9376 26.5233380480905 COL4A2/COL4A1/COL3A1/FN1 9.97255724593064 Human Diseases Infectious disease: parasitic hsa05146 Amoebiasis 4/14 103/9376 26.0083217753121 COL4A2/COL4A1/COL3A1/FN1 9.86866413712897 Environmental Information Processing Signaling molecules and interaction hsa04512 ECM-receptor interaction 3/14 89/9376 22.5746388443018 COL4A2/COL4A1/FN1 7.90799074962492 Cellular Processes Cell motility hsa04820 Cytoskeleton in muscle cells 4/14 233/9376 11.4972409564684 COL4A2/COL4A1/COL3A1/FN1 6.27442748610498 Human Diseases Cancer: specific types hsa05222 Small cell lung cancer 3/14 93/9376 21.6036866359447 COL4A2/COL4A1/FN1 7.72160484467647 Organismal Systems Endocrine system hsa04926 Relaxin signaling pathway 3/14 130/9376 15.4549450549451 COL4A2/COL4A1/COL3A1 6.41765718471201 NA NA hsa04518 Integrin signaling 3/14 154/9376 13.0463821892393 COL4A2/COL4A1/FN1 5.82867414851888 Cellular Processes Cellular community - eukaryotes hsa04510 Focal adhesion 3/14 203/9376 9.8972554539057 COL4A2/COL4A1/FN1 4.95579941249136 Human Diseases Infectious disease: viral hsa05165 Human papillomavirus infection 3/14 333/9376 6.03346203346203 COL4A2/COL4A1/FN1 3.61657924922403 Organismal Systems Immune system hsa04670 Leukocyte transendothelial migration 2/14 116/9376 11.5467980295567 PECAM1/JAM2 4.41986972015826 Environmental Information Processing Signal transduction hsa04151 PI3K-Akt signaling pathway 3/14 362/9376 5.55011838989739 COL4A2/COL4A1/FN1 3.41415742861251 Environmental Information Processing Signaling molecules and interaction hsa04514 Cell adhesion molecule (CAM) interaction 2/14 160/9376 8.37142857142857 PECAM1/JAM2 3.63668560538985 Organismal Systems Endocrine system hsa04614 Renin-angiotensin system 1/14 23/9376 29.1180124223602 PRCP 5.2208162348275 NA NA hsa04382 Cornified envelope formation 2/14 217/9376 6.1724818959842 COL4A2/COL4A1 2.98105613648415 Environmental Information Processing Signaling molecules and interaction hsa04060 Cytokine-cytokine receptor interaction 2/14 298/9376 4.49472674976031 TNFSF10/LIFR 2.37078190980258 Human Diseases Infectious disease: parasitic hsa05144 Malaria 1/14 50/9376 13.3942857142857 PECAM1 3.39800597022494 Human Diseases Cancer: specific types hsa05211 Renal cell carcinoma 1/14 70/9376 9.56734693877551 EPAS1 2.78214132889472 Human Diseases Infectious disease: bacterial hsa05120 Epithelial cell signaling in Helicobacter pylori infection 1/14 71/9376 9.43259557344065 JAM2 2.75802116976318 Genetic Information Processing Folding, sorting and degradation hsa03018 RNA degradation 1/14 78/9376 8.58608058608059 PABPC1 2.60156882613943 Human Diseases Infectious disease: bacterial hsa05100 Bacterial invasion of epithelial cells 1/14 78/9376 8.58608058608059 FN1 2.60156882613943 Organismal Systems Immune system hsa04610 Complement and coagulation cascades 1/14 88/9376 7.61038961038961 A2M 2.40919874084779 Environmental Information Processing Signaling molecules and interaction hsa04061 Viral protein interaction with cytokine and cytokine receptor 1/14 100/9376 6.69714285714286 TNFSF10 2.21483856703558 Genetic Information Processing Translation hsa03015 mRNA surveillance pathway 1/14 103/9376 6.50208044382802 PABPC1 2.17120462714163 Environmental Information Processing Signal transduction hsa04066 HIF-1 signaling pathway 1/14 110/9376 6.08831168831169 EPAS1 2.07581783392319 Organismal Systems Immune system hsa04611 Platelet activation 1/14 126/9376 5.31519274376417 COL3A1 1.88573187730759 Environmental Information Processing Signal transduction hsa04068 FoxO signaling pathway 1/14 133/9376 5.03544575725027 TNFSF10 1.8124924062311 Organismal Systems Immune system hsa04650 Natural killer cell mediated cytotoxicity 1/14 133/9376 5.03544575725027 TNFSF10 1.8124924062311 Cellular Processes Cell growth and death hsa04210 Apoptosis 1/14 137/9376 4.88842544316997 TNFSF10 1.77291091533355 Human Diseases Infectious disease: bacterial hsa05135 Yersinia infection 1/14 138/9376 4.85300207039337 FN1 1.76325508215894 Environmental Information Processing Signal transduction hsa04371 Apelin signaling pathway 1/14 140/9376 4.78367346938776 APLNR 1.74421912102771 Human Diseases Cardiovascular disease hsa05418 Fluid shear stress and atherosclerosis 1/14 142/9376 4.71629778672032 PECAM1 1.72554019963292 Cellular Processes Cellular community - eukaryotes hsa04550 Signaling pathways regulating pluripotency of stem cells 1/14 144/9376 4.65079365079365 LIFR 1.70720617269544 Cellular Processes Transport and catabolism hsa04148 Efferocytosis 1/14 157/9376 4.26569608735214 PECAM1 1.59569183303925 Cellular Processes Cell growth and death hsa04217 Necroptosis 1/14 168/9376 3.98639455782313 TNFSF10 1.5103740269092 Environmental Information Processing Signal transduction hsa04630 JAK-STAT signaling pathway 1/14 168/9376 3.98639455782313 LIFR 1.5103740269092 Cellular Processes Cellular community - eukaryotes hsa04530 Tight junction 1/14 170/9376 3.93949579831933 JAM2 1.49564029348086 Human Diseases Infectious disease: viral hsa05164 Influenza A 1/14 173/9376 3.87118084227911 TNFSF10 1.47395500361466 Human Diseases Infectious disease: bacterial hsa05130 Pathogenic Escherichia coli infection 1/14 200/9376 3.34857142857143 TNFSF10 1.29824723472625 Human Diseases Cancer: overview hsa05205 Proteoglycans in cancer 1/14 204/9376 3.28291316526611 FN1 1.27478748424117 Human Diseases Cardiovascular disease hsa05415 Diabetic cardiomyopathy 1/14 205/9376 3.26689895470383 COL3A1 1.26901303667406 Human Diseases Cardiovascular disease hsa05417 Lipid and atherosclerosis 1/14 216/9376 3.1005291005291 TNFSF10 1.20773924561396 Cellular Processes Cell motility hsa04810 Regulation of actin cytoskeleton 1/14 232/9376 2.88669950738916 FN1 1.12523687891964 Human Diseases Infectious disease: bacterial hsa05132 Salmonella infection 1/14 248/9376 2.70046082949309 TNFSF10 1.04946991843418 NA NA hsa04517 IgSF CAM signaling 1/14 299/9376 2.23984710941233 JAM2 0.842554297200082 Environmental Information Processing Signaling molecules and interaction hsa04080 Neuroactive ligand-receptor interaction 1/14 370/9376 1.81003861003861 APLNR 0.614760490081327