category	subcategory	ID	Description	GeneRatio	BgRatio	FoldEnrichment	geneName	zScore
Organismal Systems	Immune system	hsa04612	Antigen processing and presentation	12/109	82/9376	12.5880510181249	CD74/HLA-B/HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-A/CALR/CANX/CTSS/HLA-DQB1/HLA-C	11.429975417635
Cellular Processes	Transport and catabolism	hsa04145	Phagosome	15/109	155/9376	8.32435631843741	HLA-B/HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-A/COLEC12/CALR/CANX/CTSS/HLA-DQB1/OLR1/ITGB5/MSR1/HLA-C	9.97184702765336
Human Diseases	Immune disease	hsa05320	Autoimmune thyroid disease	9/109	54/9376	14.3363914373089	HLA-B/HLA-DRA/HLA-DRB1/CGA/HLA-DPA1/HLA-DPB1/HLA-A/HLA-DQB1/HLA-C	10.6588406682721
Human Diseases	Immune disease	hsa05330	Allograft rejection	8/109	39/9376	17.6447894613032	HLA-B/HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-A/HLA-DQB1/HLA-C	11.2963004775319
Human Diseases	Endocrine and metabolic disease	hsa04940	Type I diabetes mellitus	8/109	44/9376	15.6396997497915	HLA-B/HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-A/HLA-DQB1/HLA-C	10.5560259352451
Human Diseases	Immune disease	hsa05332	Graft-versus-host disease	8/109	45/9376	15.2921508664628	HLA-B/HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-A/HLA-DQB1/HLA-C	10.4224317469091
Human Diseases	Immune disease	hsa05310	Asthma	7/109	32/9376	18.8165137614679	HLA-DRA/HLA-DRB1/FCER1G/HLA-DPA1/HLA-DPB1/PRG2/HLA-DQB1	10.9486508784955
Human Diseases	Cardiovascular disease	hsa05416	Viral myocarditis	9/109	70/9376	11.059501965924	HLA-B/HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/EIF4G2/HLA-A/HLA-DQB1/HLA-C	9.1616412430323
Human Diseases	Infectious disease: bacterial	hsa05150	Staphylococcus aureus infection	9/109	99/9376	7.81984987489575	HLA-DRA/HLA-DRB1/HLA-DPA1/C1QB/C1QA/HLA-DPB1/CFD/HLA-DQB1/C1QC	7.3980615346404
Environmental Information Processing	Signaling molecules and interaction	hsa04514	Cell adhesion molecule (CAM) interaction	10/109	160/9376	5.37614678899083	HLA-B/HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-A/PTPRF/ITGB8/HLA-DQB1/HLA-C	6.05494140934089
Human Diseases	Infectious disease: viral	hsa05168	Herpes simplex virus 1 infection	10/109	180/9376	4.77879714576962	CD74/HLA-B/HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-A/CALR/HLA-DQB1/HLA-C	5.5516190271974
Organismal Systems	Immune system	hsa04610	Complement and coagulation cascades	7/109	88/9376	6.84236864053378	SERPINE2/C1QB/C1QA/F5/CFD/C1QC/A2M	5.97170705285978
Cellular Processes	Cell motility	hsa04820	Cytoskeleton in muscle cells	11/109	233/9376	4.06095208095444	FBN2/HSPG2/FBN1/VIM/FN1/FBLN1/BGN/ITGB8/COL1A1/ITGB5/COL3A1	5.13120584250187
Human Diseases	Infectious disease: viral	hsa05169	Epstein-Barr virus infection	10/109	205/9376	4.19601700604162	HLA-B/HLA-DRA/HLA-DRB1/VIM/HLA-DPA1/HLA-DPB1/HLA-A/CALR/HLA-DQB1/HLA-C	5.01772633083721
Human Diseases	Infectious disease: bacterial	hsa05152	Tuberculosis	9/109	181/9376	4.27715545643469	CD74/HLA-DRA/HLA-DRB1/FCER1G/HLA-DPA1/HLA-DPB1/CTSD/CTSS/HLA-DQB1	4.82825022653495
Human Diseases	Immune disease	hsa05322	Systemic lupus erythematosus	8/109	143/9376	4.81221530762815	HLA-DRA/HLA-DRB1/HLA-DPA1/C1QB/C1QA/HLA-DPB1/HLA-DQB1/C1QC	4.98199546080475
Human Diseases	Infectious disease: viral	hsa05166	Human T-cell leukemia virus 1 infection	10/109	224/9376	3.84010484927916	HLA-B/HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-A/CALR/CANX/HLA-DQB1/HLA-C	4.66583828629237
Organismal Systems	Immune system	hsa04672	Intestinal immune network for IgA production	5/109	50/9376	8.60183486238532	HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-DQB1	5.84500696876735
Organismal Systems	Digestive system	hsa04979	Cholesterol metabolism	5/109	52/9376	8.27099505998589	APOE/APOC1/LRP2/LPL/LRP1	5.70195380667332
Environmental Information Processing	Signaling molecules and interaction	hsa04512	ECM-receptor interaction	6/109	89/9376	5.79898979486651	HSPG2/SPP1/FN1/ITGB8/COL1A1/ITGB5	4.93328734983903
Human Diseases	Immune disease	hsa05321	Inflammatory bowel disease	5/109	66/9376	6.51654156241312	HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-DQB1	4.87745563198738
Organismal Systems	Immune system	hsa04640	Hematopoietic cell lineage	6/109	100/9376	5.16110091743119	HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/CSF3R/HLA-DQB1	4.53687887160924
Organismal Systems	Immune system	hsa04659	Th17 cell differentiation	6/109	109/9376	4.73495497012036	HLA-DRA/HLA-DRB1/IL6ST/HLA-DPA1/HLA-DPB1/HLA-DQB1	4.25361661107714
NA	NA	hsa04518	Integrin signaling	7/109	154/9376	3.90992493744787	FBN1/CTNNB1/SPP1/FN1/ITGB8/COL1A1/ITGB5	3.94874322232837
Human Diseases	Infectious disease: parasitic	hsa05140	Leishmaniasis	5/109	78/9376	5.51399670665726	HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-DQB1	4.34153267534798
Cellular Processes	Transport and catabolism	hsa04148	Efferocytosis	7/109	157/9376	3.83521299596798	C1QB/C1QA/BSG/CALR/C1QC/ITGB5/LRP1	3.88528530314355
Organismal Systems	Immune system	hsa04658	Th1 and Th2 cell differentiation	5/109	93/9376	4.62464239913189	HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-DQB1	3.80970871150407
Human Diseases	Immune disease	hsa05323	Rheumatoid arthritis	5/109	95/9376	4.52728150651859	HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-DQB1	3.74743271063543
Human Diseases	Infectious disease: viral	hsa05171	Coronavirus disease - COVID-19	8/109	238/9376	2.89137306298666	RPL39/IL6ST/RPS28/C1QB/C1QA/RPS27/CFD/C1QC	3.20530533823221
Human Diseases	Cancer: overview	hsa05205	Proteoglycans in cancer	7/109	204/9376	2.95161000179889	HSPG2/CTNNB1/FN1/TIMP3/IGF2/COL1A1/ITGB5	3.05636629344699
Human Diseases	Infectious disease: parasitic	hsa05145	Toxoplasmosis	5/109	112/9376	3.84010484927916	HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-DQB1	3.27924161831485
Human Diseases	Cardiovascular disease	hsa05415	Diabetic cardiomyopathy	7/109	205/9376	2.93721190422913	CTSD/NDUFA3/UQCRQ/UQCR10/NDUFB1/COL1A1/COL3A1	3.04141034352658
Organismal Systems	Endocrine system	hsa04918	Thyroid hormone synthesis	4/109	75/9376	4.58764525993884	CGA/LRP2/TTR/CANX	3.38302034349549
Human Diseases	Infectious disease: viral	hsa05165	Human papillomavirus infection	9/109	333/9376	2.32482023307711	HLA-B/CTNNB1/SPP1/FN1/HLA-A/ITGB8/COL1A1/ITGB5/HLA-C	2.66963636284226
Organismal Systems	Immune system	hsa04650	Natural killer cell mediated cytotoxicity	5/109	133/9376	3.23377250465614	HLA-B/TYROBP/FCER1G/HLA-A/HLA-C	2.81376349267558
Environmental Information Processing	Signal transduction	hsa04151	PI3K-Akt signaling pathway	9/109	362/9376	2.13857772821734	SPP1/FN1/CSH1/CSF3R/ITGB8/IGF2/PRLR/COL1A1/ITGB5	2.39600377716548
Metabolism	Lipid metabolism	hsa00600	Sphingolipid metabolism	3/109	55/9376	4.69190992493745	PLPP3/PSAP/HEXB	2.97803976861096
Cellular Processes	Cellular community - eukaryotes	hsa04510	Focal adhesion	6/109	203/9376	2.54241424504	CTNNB1/SPP1/FN1/ITGB8/COL1A1/ITGB5	2.40947628069183
Human Diseases	Infectious disease: parasitic	hsa05142	Chagas disease	4/109	103/9376	3.34051839315935	C1QB/C1QA/CALR/C1QC	2.5902986937332
Human Diseases	Infectious disease: parasitic	hsa05146	Amoebiasis	4/109	103/9376	3.34051839315935	FN1/HSPB1/COL1A1/COL3A1	2.5902986937332
Organismal Systems	Digestive system	hsa04978	Mineral absorption	3/109	61/9376	4.23041058805835	FTL/SLC40A1/ATP2B1	2.74511484647624
Human Diseases	Neurodegenerative disease	hsa05020	Prion disease	7/109	275/9376	2.18955796497081	C1QB/C1QA/NDUFA3/UQCRQ/UQCR10/NDUFB1/C1QC	2.17138435637361
Environmental Information Processing	Signal transduction	hsa04630	JAK-STAT signaling pathway	5/109	168/9376	2.56006989951944	IL6ST/CSH1/CSF3R/PRLR/CSF2RB	2.21281623306038
Human Diseases	Infectious disease: viral	hsa05164	Influenza A	5/109	173/9376	2.48607943999576	HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/HLA-DQB1	2.1395856277326
Organismal Systems	Endocrine system	hsa03320	PPAR signaling pathway	3/109	76/9376	3.39546112988894	LPL/SLC27A2/OLR1	2.27396489400917
Genetic Information Processing	Transcription	hsa03020	RNA polymerase	2/109	34/9376	5.05990286022666	POLR2L/POLR3K	2.57196157053582
Human Diseases	Infectious disease: bacterial	hsa05100	Bacterial invasion of epithelial cells	3/109	78/9376	3.30839802399435	CTNNB1/FN1/CLTC	2.22020220663869
Human Diseases	Infectious disease: bacterial	hsa05133	Pertussis	3/109	78/9376	3.30839802399435	C1QB/C1QA/C1QC	2.22020220663869
Cellular Processes	Transport and catabolism	hsa04142	Lysosome biogenesis	6/109	250/9376	2.06444036697248	PSAP/CTSD/LAPTM5/HEXB/CLTC/CTSS	1.85003699827308
Metabolism	Energy metabolism	hsa00190	Oxidative phosphorylation	4/109	138/9376	2.49328546735806	NDUFA3/UQCRQ/UQCR10/NDUFB1	1.91656127363484
Human Diseases	Infectious disease: viral	hsa05167	Kaposi sarcoma-associated herpesvirus infection	5/109	196/9376	2.19434562815952	HLA-B/CTNNB1/IL6ST/HLA-A/HLA-C	1.83259300663166
Human Diseases	Cardiovascular disease	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	3/109	86/9376	3.00064006827395	CTNNB1/ITGB8/ITGB5	2.02134124037689
Human Diseases	Neurodegenerative disease	hsa05010	Alzheimer disease	8/109	388/9376	1.77357419842996	APOE/CTNNB1/NDUFA3/LPL/UQCRQ/UQCR10/NDUFB1/LRP1	1.68777913075254
Cellular Processes	Cell growth and death	hsa04216	Ferroptosis	2/109	42/9376	4.0961118392311	FTL/SLC40A1	2.18090472131335
Human Diseases	Endocrine and metabolic disease	hsa04936	Alcoholic liver disease	4/109	144/9376	2.38939857288481	CTNNB1/C1QB/C1QA/C1QC	1.8221725596752
Metabolism	Glycan biosynthesis and metabolism	hsa00513	Various types of N-glycan biosynthesis	2/109	44/9376	3.90992493744787	B4GALT1/HEXB	2.09821537560931
Human Diseases	Endocrine and metabolic disease	hsa04932	Non-alcoholic fatty liver disease	4/109	157/9376	2.19155028341027	NDUFA3/UQCRQ/UQCR10/NDUFB1	1.63286243773367
Metabolism	Glycan biosynthesis and metabolism	hsa00514	Other types of O-glycan biosynthesis	2/109	49/9376	3.51095300505523	GALNT11/B4GALT1	1.91115073520086
NA	NA	hsa04081	Hormone signaling	5/109	219/9376	1.96388923798752	CGA/CSH1/SLC40A1/IGF2/PRLR	1.56531550571439
Human Diseases	Endocrine and metabolic disease	hsa04933	AGE-RAGE signaling pathway in diabetic complications	3/109	101/9376	2.55500045417386	FN1/COL1A1/COL3A1	1.70397631408851
Organismal Systems	Endocrine system	hsa04913	Ovarian steroidogenesis	2/109	52/9376	3.30839802399435	CGA/HSD17B1	1.81025826474119
Human Diseases	Infectious disease: viral	hsa05163	Human cytomegalovirus infection	5/109	227/9376	1.89467728246373	HLA-B/CTNNB1/HLA-A/CALR/HLA-C	1.47986408508564
Human Diseases	Cancer: overview	hsa05208	Chemical carcinogenesis - reactive oxygen species	5/109	227/9376	1.89467728246373	SLC26A2/NDUFA3/UQCRQ/UQCR10/NDUFB1	1.47986408508564
Organismal Systems	Excretory system	hsa04961	Endocrine and other factor-regulated calcium reabsorption	2/109	53/9376	3.24597541976805	CLTC/ATP2B1	1.77825646926674
Environmental Information Processing	Signaling molecules and interaction	hsa04060	Cytokine-cytokine receptor interaction	6/109	298/9376	1.73191305954067	IL6ST/CSH1/CSF3R/ACVRL1/PRLR/CSF2RB	1.39252129353721
Metabolism	Glycan biosynthesis and metabolism	hsa00510	N-Glycan biosynthesis	2/109	56/9376	3.07208387942333	B4GALT1/MGAT5	1.68664116203414
Genetic Information Processing	Folding, sorting and degradation	hsa04141	Protein processing in endoplasmic reticulum	4/109	174/9376	1.97743330169777	P4HB/CALR/CANX/CKAP4	1.41139945999508
Human Diseases	Neurodegenerative disease	hsa05016	Huntington disease	6/109	308/9376	1.67568211604909	POLR2L/NDUFA3/UQCRQ/UQCR10/NDUFB1/CLTC	1.30764944060664
Metabolism	Glycan biosynthesis and metabolism	hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	1/109	14/9376	6.14416775884666	B4GALT1	2.08893116017768
Metabolism	Glycan biosynthesis and metabolism	hsa00604	Glycosphingolipid biosynthesis - ganglio series	1/109	15/9376	5.73455657492355	HEXB	1.99018350783859
Metabolism	Glycan biosynthesis and metabolism	hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	1/109	16/9376	5.37614678899083	HEXB	1.89995473230093
Metabolism	Lipid metabolism	hsa00561	Glycerolipid metabolism	2/109	65/9376	2.64671841919548	PLPP3/LPL	1.44479810697021
Organismal Systems	Endocrine system	hsa04929	GnRH secretion	2/109	65/9376	2.64671841919548	SPP1/CGA	1.44479810697021
NA	NA	hsa03273	Virion - Lassa virus and SFTS virus	1/109	17/9376	5.05990286022666	NRP2	1.81699898711516
Organismal Systems	Immune system	hsa04611	Platelet activation	3/109	126/9376	2.04805591961555	FCER1G/COL1A1/COL3A1	1.2844824272384
Metabolism	Glycan biosynthesis and metabolism	hsa00511	Other glycan degradation	1/109	18/9376	4.77879714576962	HEXB	1.74031401017258
Metabolism	Glycan biosynthesis and metabolism	hsa00531	Glycosaminoglycan degradation	1/109	19/9376	4.52728150651859	HEXB	1.66908291930711
Organismal Systems	Endocrine system	hsa04917	Prolactin signaling pathway	2/109	71/9376	2.42305207391136	CGA/PRLR	1.30533229770492
Cellular Processes	Cell growth and death	hsa04210	Apoptosis	3/109	137/9376	1.88361347351503	CTSD/CTSS/CSF2RB	1.12989850792997
Human Diseases	Cancer: overview	hsa05203	Viral carcinogenesis	4/109	205/9376	1.67840680241665	HLA-B/IL6ST/HLA-A/HLA-C	1.06509435621594
Metabolism	Glycan biosynthesis and metabolism	hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	1/109	21/9376	4.0961118392311	CHPF	1.54040066413932
Metabolism	Amino acid metabolism	hsa00340	Histidine metabolism	1/109	22/9376	3.90992493744787	AOC1	1.48191655472641
Metabolism	Glycan biosynthesis and metabolism	hsa00515	Mannose type O-glycan biosynthesis	1/109	23/9376	3.7399282010371	B4GALT1	1.42677975676345
Human Diseases	Infectious disease: viral	hsa05170	Human immunodeficiency virus 1 infection	4/109	214/9376	1.60781960044585	HLA-B/HLA-A/CALR/HLA-C	0.97547411458378
Organismal Systems	Immune system	hsa04623	Cytosolic DNA-sensing pathway	2/109	83/9376	2.07273129214104	POLR2L/POLR3K	1.06458742680865
Genetic Information Processing	Translation	hsa03010	Ribosome	4/109	222/9376	1.54988015538474	RPL39/RPS28/RPS27/MRPS14	0.899225026984283
Organismal Systems	Circulatory system	hsa04260	Cardiac muscle contraction	2/109	87/9376	1.97743330169777	UQCRQ/UQCR10	0.993325494491115
Cellular Processes	Cell growth and death	hsa04218	Cellular senescence	3/109	157/9376	1.6436627125577	HLA-B/HLA-A/HLA-C	0.882054815930382
Metabolism	Glycan biosynthesis and metabolism	hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	1/109	28/9376	3.07208387942333	B4GALT1	1.19084791728458
Metabolism	Metabolism of cofactors and vitamins	hsa00790	Folate biosynthesis	1/109	28/9376	3.07208387942333	GGH	1.19084791728458
Cellular Processes	Cell motility	hsa04810	Regulation of actin cytoskeleton	4/109	232/9376	1.48307497627333	TMSB4X/FN1/ITGB8/ITGB5	0.808015572168794
Environmental Information Processing	Signal transduction	hsa04392	Hippo signaling pathway - multiple species	1/109	29/9376	2.96614995254666	TEAD1	1.15002907523853
Organismal Systems	Environmental adaptation	hsa04714	Thermogenesis	4/109	235/9376	1.4641421042358	NDUFA3/UQCRQ/UQCR10/NDUFB1	0.781479066702161
Cellular Processes	Cellular community - eukaryotes	hsa04520	Adherens junction	2/109	93/9376	1.84985695965276	CTNNB1/PTPRF	0.893248797039099
Organismal Systems	Digestive system	hsa04970	Salivary secretion	2/109	93/9376	1.84985695965276	LYZ/ATP2B1	0.893248797039099
Human Diseases	Drug resistance: antineoplastic	hsa01523	Antifolate resistance	1/109	30/9376	2.86727828746177	GGH	1.11092845800031
Organismal Systems	Immune system	hsa04657	IL-17 signaling pathway	2/109	94/9376	1.83017763029475	S100A8/S100A9	0.877290602533101
Metabolism	Carbohydrate metabolism	hsa00630	Glyoxylate and dicarboxylate metabolism	1/109	31/9376	2.77478543947914	ACSS1	1.07341177926845
Metabolism	Carbohydrate metabolism	hsa00052	Galactose metabolism	1/109	32/9376	2.68807339449541	B4GALT1	1.03735930053717
Metabolism	Carbohydrate metabolism	hsa00640	Propanoate metabolism	1/109	32/9376	2.68807339449541	ACSS1	1.03735930053717
Organismal Systems	Immune system	hsa04666	Fc gamma R-mediated phagocytosis	2/109	98/9376	1.75547650252762	PLPP3/MARCKS	0.815335065255951
Human Diseases	Cardiovascular disease	hsa05410	Hypertrophic cardiomyopathy	2/109	99/9376	1.7377444166435	ITGB8/ITGB5	0.80029306968424
Cellular Processes	Transport and catabolism	hsa04144	Endocytosis	4/109	250/9376	1.37629357798165	HLA-B/HLA-A/CLTC/HLA-C	0.654012251957947
Organismal Systems	Digestive system	hsa04974	Protein digestion and absorption	2/109	103/9376	1.67025919657967	COL1A1/COL3A1	0.741789308914348
Environmental Information Processing	Signal transduction	hsa04310	Wnt signaling pathway	3/109	178/9376	1.44974744871663	CTNNB1/LGR5/SERPINF1	0.656993862660862
Metabolism	Glycan biosynthesis and metabolism	hsa00512	Mucin type O-glycan biosynthesis	1/109	36/9376	2.38939857288481	GALNT11	0.90580344145626
Human Diseases	Cardiovascular disease	hsa05414	Dilated cardiomyopathy	2/109	105/9376	1.63844473569244	ITGB8/ITGB5	0.713483567203712
Human Diseases	Cancer: specific types	hsa05215	Prostate cancer	2/109	106/9376	1.62298770988402	SPINT1/CTNNB1	0.699554976348628
Human Diseases	Cancer: specific types	hsa05216	Thyroid cancer	1/109	37/9376	2.32482023307711	CTNNB1	0.875662864142244
Metabolism	Carbohydrate metabolism	hsa00520	Amino sugar and nucleotide sugar metabolism	1/109	38/9376	2.2636407532593	HEXB	0.846482127510864
Human Diseases	Endocrine and metabolic disease	hsa04931	Insulin resistance	2/109	109/9376	1.57831832337345	PTPRF/SLC27A2	0.65862759965546
Environmental Information Processing	Signal transduction	hsa04350	TGF-beta signaling pathway	2/109	110/9376	1.56396997497915	FBN1/LTBP1	0.645261099220172
Human Diseases	Neurodegenerative disease	hsa05012	Parkinson disease	4/109	268/9376	1.28385594960975	NDUFA3/UQCRQ/UQCR10/NDUFB1	0.511308712685542
Metabolism	Amino acid metabolism	hsa00380	Tryptophan metabolism	1/109	42/9376	2.04805591961555	AOC1	0.73825178868784
Organismal Systems	Digestive system	hsa04975	Fat digestion and absorption	1/109	43/9376	2.00042671218263	PLPP3	0.713079875118165
Metabolism	Metabolism of cofactors and vitamins	hsa00860	Porphyrin metabolism	1/109	46/9376	1.86996410051855	FTL	0.641458746483438
Metabolism	Carbohydrate metabolism	hsa00620	Pyruvate metabolism	1/109	47/9376	1.83017763029475	ACSS1	0.618773512655146
Environmental Information Processing	Signal transduction	hsa04071	Sphingolipid signaling pathway	2/109	125/9376	1.37629357798165	FCER1G/CTSD	0.459321503968833
NA	NA	hsa03272	Virion - Hepatitis viruses	1/109	48/9376	1.79204892966361	HSPG2	0.596633544541223
Metabolism	Amino acid metabolism	hsa00330	Arginine and proline metabolism	1/109	50/9376	1.72036697247706	AOC1	0.553886009157147
Human Diseases	Infectious disease: parasitic	hsa05144	Malaria	1/109	50/9376	1.72036697247706	LRP1	0.553886009157147
Organismal Systems	Endocrine system	hsa04926	Relaxin signaling pathway	2/109	130/9376	1.32335920959774	COL1A1/COL3A1	0.402632911801404
Metabolism	Lipid metabolism	hsa00565	Ether lipid metabolism	1/109	51/9376	1.68663428674222	PLPP3	0.533231085568217
NA	NA	hsa04382	Cornified envelope formation	3/109	217/9376	1.18919375977677	S100A8/S100A9/S100A4	0.305803147381903
Environmental Information Processing	Signal transduction	hsa04340	Hedgehog signaling pathway	1/109	56/9376	1.53604193971166	LRP2	0.436329054567971
Organismal Systems	Endocrine system	hsa04923	Regulation of lipolysis in adipocytes	1/109	59/9376	1.4579381122687	CGA	0.382669680059804
Human Diseases	Cancer: specific types	hsa05213	Endometrial cancer	1/109	59/9376	1.4579381122687	CTNNB1	0.382669680059804
Cellular Processes	Cellular community - eukaryotes	hsa04550	Signaling pathways regulating pluripotency of stem cells	2/109	144/9376	1.19469928644241	CTNNB1/IL6ST	0.255344797430641
Environmental Information Processing	Signal transduction	hsa04370	VEGF signaling pathway	1/109	60/9376	1.43363914373089	HSPB1	0.365442176751592
Environmental Information Processing	Signal transduction	hsa04072	Phospholipase D signaling pathway	2/109	149/9376	1.15460870636045	PLPP3/FCER1G	0.206312777547378
Organismal Systems	Nervous system	hsa04723	Retrograde endocannabinoid signaling	2/109	149/9376	1.15460870636045	NDUFA3/NDUFB1	0.206312777547378
Metabolism	Amino acid metabolism	hsa00310	Lysine degradation	1/109	63/9376	1.36537061307703	EHMT1	0.315564683316398
Genetic Information Processing	Replication and repair	hsa03420	Nucleotide excision repair	1/109	63/9376	1.36537061307703	POLR2L	0.315564683316398
Human Diseases	Cancer: specific types	hsa05217	Basal cell carcinoma	1/109	63/9376	1.36537061307703	CTNNB1	0.315564683316398
Metabolism	Lipid metabolism	hsa00140	Steroid hormone biosynthesis	1/109	66/9376	1.30330831248262	HSD17B1	0.268170341908896
Metabolism	Carbohydrate metabolism	hsa00010	Glycolysis / Gluconeogenesis	1/109	67/9376	1.28385594960975	ACSS1	0.252879249141781
Environmental Information Processing	Signal transduction	hsa04390	Hippo signaling pathway	2/109	157/9376	1.09577514170514	CTNNB1/TEAD1	0.13124719412709
Organismal Systems	Immune system	hsa04664	Fc epsilon RI signaling pathway	1/109	69/9376	1.24664273367903	FCER1G	0.223006396107136
Human Diseases	Cancer: specific types	hsa05225	Hepatocellular carcinoma	2/109	170/9376	1.01198057204533	CTNNB1/IGF2	0.0170960522392198
Metabolism	Carbohydrate metabolism	hsa00562	Inositol phosphate metabolism	1/109	78/9376	1.10279934133145	ISYNA1	0.0988717379293902
Organismal Systems	Nervous system	hsa04721	Synaptic vesicle cycle	1/109	79/9376	1.08883985599814	CLTC	0.0859962040958149
Metabolism	Xenobiotics biodegradation and metabolism	hsa00983	Drug metabolism - other enzymes	1/109	82/9376	1.0490042515104	ITPA	0.0483357718435527
Cellular Processes	Transport and catabolism	hsa04146	Peroxisome	1/109	83/9376	1.03636564607052	SLC27A2	0.0360895686161819
Human Diseases	Neurodegenerative disease	hsa05014	Amyotrophic lateral sclerosis	4/109	368/9376	0.934982050259274	NDUFA3/UQCRQ/UQCR10/NDUFB1	-0.13799784253986
Environmental Information Processing	Signaling molecules and interaction	hsa04080	Neuroactive ligand-receptor interaction	4/109	370/9376	0.929928093230846	TAC3/CGA/CSH1/PRLR	-0.149144805423764
Metabolism	Global and overview maps	hsa01232	Nucleotide metabolism	1/109	85/9376	1.01198057204533	ITPA	0.0120333096826741
Human Diseases	Cancer: specific types	hsa05210	Colorectal cancer	1/109	87/9376	0.988716650848887	CTNNB1	-0.011466806334076
Organismal Systems	Aging	hsa04211	Longevity regulating pathway	1/109	90/9376	0.955759429153925	EHMT1	-0.0457358697978975
Human Diseases	Neurodegenerative disease	hsa05022	Pathways of neurodegeneration - multiple diseases	5/109	480/9376	0.896024464831804	CTNNB1/NDUFA3/UQCRQ/UQCR10/NDUFB1	-0.253620118780573
Organismal Systems	Endocrine system	hsa04912	GnRH signaling pathway	1/109	93/9376	0.924928479826379	CGA	-0.0789045077825599
Human Diseases	Cancer: specific types	hsa05222	Small cell lung cancer	1/109	93/9376	0.924928479826379	FN1	-0.0789045077825599
NA	NA	hsa04517	IgSF CAM signaling	3/109	299/9376	0.863060354085484	CTNNB1/PTPRF/NRP2	-0.26098943828532
Organismal Systems	Endocrine system	hsa04925	Aldosterone synthesis and secretion	1/109	98/9376	0.877738251263808	ATP2B1	-0.13194889655815
Human Diseases	Cancer: overview	hsa05231	Choline metabolism in cancer	1/109	99/9376	0.86887220832175	PLPP3	-0.142245282452355
Environmental Information Processing	Signaling molecules and interaction	hsa04061	Viral protein interaction with cytokine and cytokine receptor	1/109	100/9376	0.860183486238532	IL6ST	-0.152442971168808
Organismal Systems	Endocrine system	hsa04916	Melanogenesis	1/109	101/9376	0.851666818057953	CTNNB1	-0.162544150996352
Organismal Systems	Digestive system	hsa04972	Pancreatic secretion	1/109	102/9376	0.84331714337111	ATP2B1	-0.172550938889228
Metabolism	Lipid metabolism	hsa00564	Glycerophospholipid metabolism	1/109	104/9376	0.827099505998589	PLPP3	-0.192289468025665
Organismal Systems	Immune system	hsa04625	C-type lectin receptor signaling pathway	1/109	105/9376	0.819222367846221	FCER1G	-0.202025112979948
Organismal Systems	Immune system	hsa04620	Toll-like receptor signaling pathway	1/109	109/9376	0.789159161686727	SPP1	-0.24011965319996
Environmental Information Processing	Signal transduction	hsa04066	HIF-1 signaling pathway	1/109	110/9376	0.781984987489575	TIMP1	-0.249439886625485
Human Diseases	Cancer: overview	hsa05206	MicroRNAs in cancer	3/109	323/9376	0.798932030562104	VIM/TIMP3/MARCKS	-0.398820247522573
Environmental Information Processing	Signal transduction	hsa04024	cAMP signaling pathway	2/109	226/9376	0.761224324104896	CGA/ATP2B1	-0.394060642660651
Metabolism	Global and overview maps	hsa01200	Carbon metabolism	1/109	116/9376	0.741537488136666	ACSS1	-0.303773837548087
Organismal Systems	Immune system	hsa04670	Leukocyte transendothelial migration	1/109	116/9376	0.741537488136666	CTNNB1	-0.303773837548087
Organismal Systems	Nervous system	hsa04722	Neurotrophin signaling pathway	1/109	120/9376	0.716819571865443	MAGED1	-0.338587943593969
Organismal Systems	Endocrine system	hsa04919	Thyroid hormone signaling pathway	1/109	122/9376	0.705068431343059	CTNNB1	-0.35560326033709
Organismal Systems	Endocrine system	hsa04935	Growth hormone synthesis, secretion and action	1/109	122/9376	0.705068431343059	CSH1	-0.35560326033709
Metabolism	Nucleotide metabolism	hsa00230	Purine metabolism	1/109	128/9376	0.672018348623853	ITPA	-0.405191128552181
Human Diseases	Infectious disease: bacterial	hsa05132	Salmonella infection	2/109	248/9376	0.693696359869784	CTNNB1/PLEKHM2	-0.530175297054091
Organismal Systems	Endocrine system	hsa04910	Insulin signaling pathway	1/109	138/9376	0.623321366839516	PTPRF	-0.483449210952497
Human Diseases	Infectious disease: bacterial	hsa05135	Yersinia infection	1/109	138/9376	0.623321366839516	FN1	-0.483449210952497
Organismal Systems	Endocrine system	hsa04915	Estrogen signaling pathway	1/109	139/9376	0.618837040459376	CTSD	-0.491000488656871
Environmental Information Processing	Signal transduction	hsa04371	Apelin signaling pathway	1/109	140/9376	0.614416775884666	SPP1	-0.498504969207918
Organismal Systems	Development and regeneration	hsa04380	Osteoclast differentiation	1/109	142/9376	0.60576301847784	TYROBP	-0.513376404164336
Human Diseases	Cardiovascular disease	hsa05418	Fluid shear stress and atherosclerosis	1/109	142/9376	0.60576301847784	CTNNB1	-0.513376404164336
Human Diseases	Cancer: specific types	hsa05224	Breast cancer	1/109	148/9376	0.581205058269278	CTNNB1	-0.556939214545536
Human Diseases	Cancer: specific types	hsa05226	Gastric cancer	1/109	150/9376	0.573455657492355	CTNNB1	-0.571126610996648
Metabolism	Global and overview maps	hsa01240	Biosynthesis of cofactors	1/109	154/9376	0.558560705349696	GGH	-0.599029342780436
Organismal Systems	Circulatory system	hsa04261	Adrenergic signaling in cardiomyocytes	1/109	154/9376	0.558560705349696	ATP2B1	-0.599029342780436
Human Diseases	Endocrine and metabolic disease	hsa04934	Cushing syndrome	1/109	155/9376	0.554957087895827	CTNNB1	-0.605909877578291
Human Diseases	Infectious disease: viral	hsa05160	Hepatitis C	1/109	156/9376	0.551399670665726	CTNNB1	-0.612753403777814
Human Diseases	Infectious disease: viral	hsa05161	Hepatitis B	1/109	163/9376	0.527719930207688	HSPG2	-0.659663099509873
NA	NA	hsa04519	Cadherin signaling	3/109	404/9376	0.638750113543464	VIM/CTNNB1/TEAD1	-0.80497626460447
Environmental Information Processing	Signal transduction	hsa04022	cGMP-PKG signaling pathway	1/109	166/9376	0.51818282303526	ATP2B1	-0.6792596441839
Cellular Processes	Cell growth and death	hsa04217	Necroptosis	1/109	168/9376	0.512013979903888	FTL	-0.692163464667726
Cellular Processes	Transport and catabolism	hsa04140	Autophagy - animal	1/109	169/9376	0.508984311383747	CTSD	-0.698568430172272
Environmental Information Processing	Signal transduction	hsa04010	MAPK signaling pathway	2/109	300/9376	0.573455657492355	HSPB1/IGF2	-0.814342077220493
Organismal Systems	Development and regeneration	hsa04360	Axon guidance	1/109	184/9376	0.467491025129637	SEMA3F	-0.791152383955262
Organismal Systems	Immune system	hsa04621	NOD-like receptor signaling pathway	1/109	187/9376	0.459991169111514	TXNIP	-0.80894099553693
NA	NA	hsa04082	Neuroactive ligand signaling	1/109	199/9376	0.432253008160066	TAC3	-0.877930869564735
Human Diseases	Cancer: overview	hsa05202	Transcriptional misregulation in cancer	1/109	201/9376	0.42795198320325	SPINT1	-0.889112635522904
Environmental Information Processing	Signal transduction	hsa04015	Rap1 signaling pathway	1/109	212/9376	0.405746927471006	CTNNB1	-0.949130941934997
Human Diseases	Cardiovascular disease	hsa05417	Lipid and atherosclerosis	1/109	216/9376	0.398233095480802	OLR1	-0.97036861937274
Environmental Information Processing	Signal transduction	hsa04014	Ras signaling pathway	1/109	238/9376	0.361421632873333	IGF2	-1.08219720851822
Environmental Information Processing	Signal transduction	hsa04020	Calcium signaling pathway	1/109	254/9376	0.338654915841942	ATP2B1	-1.15885542918837