ID Description GeneRatio BgRatio RichFactor FoldEnrichment pvalue p.adjust GO:0042277 peptide binding 16/161 249/18639 0.0642570281124498 7.43904811793759 5.11846449159537e-10 2.05762272562134e-07 GO:0005178 integrin binding 13/161 161/18639 0.0807453416149068 9.34790324447359 1.44884255621815e-09 2.91217353799848e-07 GO:0042605 peptide antigen binding 8/161 45/18639 0.177777777777778 20.5813664596273 4.27632942363543e-09 5.73028142767148e-07 GO:0005201 extracellular matrix structural constituent 12/161 168/18639 0.0714285714285714 8.26929902395741 2.52609016393001e-08 2.53872061474966e-06 GO:0023026 MHC class II protein complex binding 6/161 27/18639 0.222222222222222 25.7267080745342 9.63720479886887e-08 7.74831265829057e-06 GO:0023023 MHC protein complex binding 6/161 37/18639 0.162162162162162 18.7735437300655 7.04748715340676e-07 4.0472711938136e-05 GO:0043394 proteoglycan binding 6/161 37/18639 0.162162162162162 18.7735437300655 7.04748715340676e-07 4.0472711938136e-05 GO:0140375 immune receptor activity 10/161 156/18639 0.0641025641025641 7.42116579073101 1.03853120201067e-06 4.83103853061929e-05 GO:0032395 MHC class II receptor activity 4/161 10/18639 0.4 46.3080745341615 1.08157579043715e-06 4.83103853061929e-05 GO:0050840 extracellular matrix binding 7/161 67/18639 0.104477611940299 12.0953926022064 1.77211368750236e-06 7.12389702375949e-05 GO:0008201 heparin binding 10/161 172/18639 0.0581395348837209 6.73082478694208 2.51965025319092e-06 9.20817637984317e-05 GO:0019838 growth factor binding 9/161 136/18639 0.0661764705882353 7.66126233101936 2.80888750164421e-06 9.4097731305081e-05 GO:0019955 cytokine binding 9/161 144/18639 0.0625 7.23563664596273 4.49891391039433e-06 0.000139120260921425 GO:0005539 glycosaminoglycan binding 11/161 242/18639 0.0454545454545455 5.26228119706381 8.47328535936999e-06 0.000243304336747624 GO:0038024 cargo receptor activity 6/161 65/18639 0.0923076923076923 10.6864787386527 2.05130404191484e-05 0.000549749483233177 GO:1901681 sulfur compound binding 11/161 275/18639 0.04 4.63080745341615 2.78627317104569e-05 0.00070005113422523 GO:0030246 carbohydrate binding 11/161 280/18639 0.0392857142857143 4.54811446317657 3.28590777942897e-05 0.000777020545488498 GO:0033218 amide binding 10/161 247/18639 0.0404858299595142 4.68705207835643 5.87156448337867e-05 0.00131131606795457 GO:0005044 scavenger receptor activity 4/161 27/18639 0.148148148148148 17.1511387163561 8.06035682931346e-05 0.00165801717040049 GO:0001540 amyloid-beta binding 6/161 83/18639 0.072289156626506 8.36892913267979 8.24884164378353e-05 0.00165801717040049 GO:0042608 T cell receptor binding 3/161 11/18639 0.272727272727273 31.5736871823828 9.91964640417126e-05 0.00181258993385311 GO:0050786 RAGE receptor binding 3/161 11/18639 0.272727272727273 31.5736871823828 9.91964640417126e-05 0.00181258993385311 GO:0003823 antigen binding 8/161 174/18639 0.0459770114942529 5.32276718783465 0.000137138148081385 0.00229281696216315 GO:0070325 lipoprotein particle receptor binding 4/161 31/18639 0.129032258064516 14.9380885594069 0.000140678275813906 0.00229281696216315 GO:0005179 hormone activity 7/161 132/18639 0.053030303030303 6.13932806324111 0.000150323140840147 0.00229281696216315 GO:0061134 peptidase regulator activity 9/161 226/18639 0.0398230088495575 4.61031715494971 0.00015656930249553 0.00229281696216315 GO:0071813 lipoprotein particle binding 4/161 32/18639 0.125 14.4712732919255 0.00015969869388201 0.00229281696216315 GO:0071814 protein-lipid complex binding 4/161 32/18639 0.125 14.4712732919255 0.00015969869388201 0.00229281696216315 GO:0002020 protease binding 7/161 136/18639 0.0514705882352941 5.95875959079284 0.000180883420388384 0.00250741844814243 GO:0005041 low-density lipoprotein particle receptor activity 3/161 15/18639 0.2 23.1540372670807 0.000266675487138938 0.00357345152766177 GO:0030228 lipoprotein particle receptor activity 3/161 18/18639 0.166666666666667 19.2950310559006 0.00046923766407301 0.00608495293410807 GO:0004866 endopeptidase inhibitor activity 7/161 161/18639 0.0434782608695652 5.03348636240886 0.000504928765335445 0.00634316761452653 GO:0043395 heparan sulfate proteoglycan binding 3/161 19/18639 0.157894736842105 18.2795031055901 0.000553697210258694 0.00674503874315136 GO:0019199 transmembrane receptor protein kinase activity 5/161 78/18639 0.0641025641025641 7.42116579073101 0.000573958472398891 0.00678621487953983 GO:0030414 peptidase inhibitor activity 7/161 169/18639 0.0414201183431953 4.79521481862619 0.000673782737243302 0.00773887601062306 GO:0030021 extracellular matrix structural constituent conferring compression resistance 3/161 22/18639 0.136363636363636 15.7868435911914 0.0008634027325952 0.00964133051397973 GO:0004857 enzyme inhibitor activity 11/161 416/18639 0.0264423076923077 3.06123088867654 0.0010022978526064 0.0108898307229127 GO:0061135 endopeptidase regulator activity 7/161 184/18639 0.0380434782608696 4.40430056710775 0.00110900510306354 0.0117321066166196 GO:0140313 molecular sequestering activity 4/161 55/18639 0.0727272727272727 8.41964991530209 0.00129839821380509 0.0133834892807601 GO:0004867 serine-type endopeptidase inhibitor activity 5/161 95/18639 0.0526315789473684 6.09316770186335 0.00140078514998165 0.0139352850309116 GO:0050750 low-density lipoprotein particle receptor binding 3/161 26/18639 0.115384615384615 13.3580984233158 0.00142126041360043 0.0139352850309116 GO:0004896 cytokine receptor activity 5/161 96/18639 0.0520833333333333 6.02969720496894 0.00146759948200371 0.0140470236134641 GO:0043236 laminin binding 3/161 29/18639 0.103448275862069 11.976226172628 0.00195991033785933 0.0183228826934756 GO:0005518 collagen binding 4/161 72/18639 0.0555555555555556 6.43167701863354 0.00349724088279059 0.0317894355243786 GO:0008271 secondary active sulfate transmembrane transporter activity 2/161 11/18639 0.181818181818182 21.0491247882552 0.00387483169327003 0.0317894355243786 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 2/161 11/18639 0.181818181818182 21.0491247882552 0.00387483169327003 0.0317894355243786 GO:0019864 IgG binding 2/161 11/18639 0.181818181818182 21.0491247882552 0.00387483169327003 0.0317894355243786 GO:0048407 platelet-derived growth factor binding 2/161 11/18639 0.181818181818182 21.0491247882552 0.00387483169327003 0.0317894355243786 GO:0097493 structural molecule activity conferring elasticity 2/161 11/18639 0.181818181818182 21.0491247882552 0.00387483169327003 0.0317894355243786 GO:0033293 monocarboxylic acid binding 4/161 79/18639 0.0506329113924051 5.86178158660272 0.00487559567725619 0.0391997892451398 GO:0048306 calcium-dependent protein binding 4/161 80/18639 0.05 5.78850931677019 0.00509827901784911 0.0401864346112812 GO:0035325 Toll-like receptor binding 2/161 13/18639 0.153846153846154 17.8107978977544 0.00543328520013192 0.0420034740471737 GO:0008191 metalloendopeptidase inhibitor activity 2/161 14/18639 0.142857142857143 16.5385980479148 0.00630304943727225 0.0478080353544046 GO:0015116 sulfate transmembrane transporter activity 2/161 15/18639 0.133333333333333 15.4360248447205 0.00723172235267737 0.0538361552921537 GO:0005504 fatty acid binding 3/161 47/18639 0.0638297872340425 7.38958636183428 0.00776606916047096 0.0567629055001696 GO:0005024 transforming growth factor beta receptor activity 2/161 16/18639 0.125 14.4712732919255 0.00821823430631758 0.057960178791924 GO:0005159 insulin-like growth factor receptor binding 2/161 16/18639 0.125 14.4712732919255 0.00821823430631758 0.057960178791924 GO:0008194 UDP-glycosyltransferase activity 5/161 145/18639 0.0344827586206897 3.99207539087599 0.0085468904121445 0.0592387921669325 GO:0042562 hormone binding 4/161 94/18639 0.0425531914893617 4.92639090788952 0.00896025230013647 0.0610349979601332 GO:0030169 low-density lipoprotein particle binding 2/161 17/18639 0.117647058823529 13.6200219218122 0.00926152954121424 0.0610349979601332 GO:0036041 long-chain fatty acid binding 2/161 17/18639 0.117647058823529 13.6200219218122 0.00926152954121424 0.0610349979601332 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 2/161 18/18639 0.111111111111111 12.8633540372671 0.0103605660258569 0.0661102784507059 GO:0034185 apolipoprotein binding 2/161 18/18639 0.111111111111111 12.8633540372671 0.0103605660258569 0.0661102784507059 GO:0003756 protein disulfide isomerase activity 2/161 19/18639 0.105263157894737 12.1863354037267 0.0115143152982802 0.0712116115370561 GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 2/161 19/18639 0.105263157894737 12.1863354037267 0.0115143152982802 0.0712116115370561 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 2/161 20/18639 0.1 11.5770186335404 0.012721762311784 0.0774870977172299 GO:0008083 growth factor activity 5/161 162/18639 0.0308641975308642 3.57315389924086 0.0133489186022561 0.0800935116135365 GO:0004714 transmembrane receptor protein tyrosine kinase activity 3/161 60/18639 0.05 5.78850931677019 0.0151103329125081 0.0878298532281977 GO:0034062 5'-3' RNA polymerase activity 2/161 22/18639 0.0909090909090909 10.5245623941276 0.0152937555372484 0.0878298532281977 GO:0097747 RNA polymerase activity 2/161 22/18639 0.0909090909090909 10.5245623941276 0.0152937555372484 0.0878298532281977 GO:1901682 sulfur compound transmembrane transporter activity 3/161 63/18639 0.0476190476190476 5.51286601597161 0.0172103217632577 0.097444357025769 GO:0050431 transforming growth factor beta binding 2/161 24/18639 0.0833333333333333 9.64751552795031 0.0180686878732542 0.100883507292336 GO:0004252 serine-type endopeptidase activity 5/161 176/18639 0.0284090909090909 3.28892574816488 0.0184637066907381 0.101676850543517 GO:0022853 active monoatomic ion transmembrane transporter activity 4/161 118/18639 0.0338983050847458 3.92441309611538 0.0192530968976289 0.103302663758324 GO:0015645 fatty acid ligase activity 2/161 25/18639 0.08 9.2616149068323 0.0195298568299319 0.103302663758324 GO:0120515 fatty acid-CoA ligase activity 2/161 25/18639 0.08 9.2616149068323 0.0195298568299319 0.103302663758324 GO:0019865 immunoglobulin binding 2/161 26/18639 0.0769230769230769 8.90539894887721 0.0210389065312928 0.107139777230415 GO:0030247 polysaccharide binding 2/161 26/18639 0.0769230769230769 8.90539894887721 0.0210389065312928 0.107139777230415 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 3/161 68/18639 0.0441176470588235 5.10750822067958 0.021054831843788 0.107139777230415 GO:0016405 CoA-ligase activity 2/161 27/18639 0.0740740740740741 8.57556935817805 0.0225949116522551 0.112727119459688 GO:0097110 scaffold protein binding 3/161 70/18639 0.0428571428571429 4.96157941437445 0.0227136733239669 0.112727119459688 GO:0097718 disordered domain specific binding 2/161 28/18639 0.0714285714285714 8.26929902395741 0.0241969591059702 0.118624116592683 GO:0004175 endopeptidase activity 8/161 405/18639 0.0197530864197531 2.28681849551415 0.0246454159525567 0.119366954372624 GO:0008236 serine-type peptidase activity 5/161 194/18639 0.0257731958762887 2.9837676890568 0.026742355296829 0.127981271777682 GO:0044183 protein folding chaperone 3/161 75/18639 0.04 4.63080745341615 0.0271635250860192 0.128467495112702 GO:0001968 fibronectin binding 2/161 30/18639 0.0666666666666667 7.71801242236025 0.0275355890156278 0.128712869584679 GO:0098631 cell adhesion mediator activity 3/161 76/18639 0.0394736842105263 4.56987577639752 0.0281053020485162 0.129304427519523 GO:0016758 hexosyltransferase activity 5/161 197/18639 0.0253807106598985 2.93832960242141 0.0283187685720399 0.129304427519523 GO:0017171 serine hydrolase activity 5/161 198/18639 0.0252525252525253 2.92348955392434 0.0288570733675224 0.129304427519523 GO:0051087 protein-folding chaperone binding 4/161 134/18639 0.0298507462686567 3.45582645777325 0.0290147825069065 0.129304427519523 GO:0016878 acid-thiol ligase activity 2/161 31/18639 0.0645161290322581 7.46904427970347 0.0292704052345189 0.129304427519523 GO:0046332 SMAD binding 3/161 79/18639 0.0379746835443038 4.39633618995204 0.0310338412557674 0.135604393313244 GO:0030296 protein tyrosine kinase activator activity 2/161 33/18639 0.0606060606060606 7.01637492941841 0.0328667124596426 0.140557642646556 GO:0140311 protein sequestering activity 2/161 33/18639 0.0606060606060606 7.01637492941841 0.0328667124596426 0.140557642646556 GO:0008376 acetylgalactosaminyltransferase activity 2/161 34/18639 0.0588235294117647 6.8100109609061 0.0347265069459631 0.14541724783622 GO:0015035 protein-disulfide reductase activity 2/161 34/18639 0.0588235294117647 6.8100109609061 0.0347265069459631 0.14541724783622 GO:0016209 antioxidant activity 3/161 86/18639 0.0348837209302326 4.03849487216525 0.0384644007909107 0.159409166164393 GO:0015036 disulfide oxidoreductase activity 2/161 40/18639 0.05 5.78850931677019 0.046696571348121 0.191551241652496 GO:0008137 NADH dehydrogenase (ubiquinone) activity 2/161 41/18639 0.0487804878048781 5.64732616270262 0.0488193977995052 0.196253979154011 GO:0016877 ligase activity, forming carbon-sulfur bonds 2/161 41/18639 0.0487804878048781 5.64732616270262 0.0488193977995052 0.196253979154011 GO:0008375 acetylglucosaminyltransferase activity 2/161 43/18639 0.0465116279069767 5.38465982955366 0.0531677099190104 0.211618013737051 GO:0003954 NADH dehydrogenase activity 2/161 44/18639 0.0454545454545455 5.26228119706381 0.0553917146841831 0.216189022359627 GO:0030020 extracellular matrix structural constituent conferring tensile strength 2/161 44/18639 0.0454545454545455 5.26228119706381 0.0553917146841831 0.216189022359627 GO:0015399 primary active transmembrane transporter activity 4/161 166/18639 0.0240963855421687 2.7896430442266 0.0560033833622508 0.216474616457931 GO:0030276 clathrin binding 2/161 46/18639 0.0434782608695652 5.03348636240886 0.0599357948971627 0.229468471891994 GO:0003735 structural constituent of ribosome 4/161 175/18639 0.0228571428571429 2.64617568766637 0.0653955123595979 0.248009395929796 GO:0001222 transcription corepressor binding 2/161 49/18639 0.0408163265306122 4.72531372797566 0.0669815075647842 0.251650149916292 GO:0016853 isomerase activity 4/161 180/18639 0.0222222222222222 2.57267080745342 0.0709472728569778 0.259012576579947 GO:0005080 protein kinase C binding 2/161 52/18639 0.0384615384615385 4.45269947443861 0.0742863150187868 0.259012576579947 GO:0016860 intramolecular oxidoreductase activity 2/161 53/18639 0.0377358490566038 4.36868627680769 0.0767757340119543 0.259012576579947 GO:0017046 peptide hormone binding 2/161 53/18639 0.0377358490566038 4.36868627680769 0.0767757340119543 0.259012576579947 GO:0031406 carboxylic acid binding 4/161 187/18639 0.0213903743315508 2.47636762214767 0.0791124206804279 0.259012576579947 GO:0009055 electron transfer activity 3/161 116/18639 0.0258620689655172 2.99405654315699 0.0792881054515251 0.259012576579947 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 2/161 54/18639 0.037037037037037 4.28778467908903 0.0792913203514613 0.259012576579947 GO:0050661 NADP binding 2/161 54/18639 0.037037037037037 4.28778467908903 0.0792913203514613 0.259012576579947 GO:0140463 chromatin-protein adaptor activity 2/161 54/18639 0.037037037037037 4.28778467908903 0.0792913203514613 0.259012576579947 GO:0043177 organic acid binding 4/161 189/18639 0.0211640211640212 2.45016267376516 0.0815281215344835 0.259012576579947 GO:0016757 glycosyltransferase activity 5/161 267/18639 0.0187265917602996 2.16798101751692 0.0821845983151873 0.259012576579947 GO:0003796 lysozyme activity 1/161 10/18639 0.1 11.5770186335404 0.0831159760666995 0.259012576579947 GO:0005131 growth hormone receptor binding 1/161 10/18639 0.1 11.5770186335404 0.0831159760666995 0.259012576579947 GO:0005381 iron ion transmembrane transporter activity 1/161 10/18639 0.1 11.5770186335404 0.0831159760666995 0.259012576579947 GO:0005528 FK506 binding 1/161 10/18639 0.1 11.5770186335404 0.0831159760666995 0.259012576579947 GO:0015658 branched-chain amino acid transmembrane transporter activity 1/161 10/18639 0.1 11.5770186335404 0.0831159760666995 0.259012576579947 GO:0019531 oxalate transmembrane transporter activity 1/161 10/18639 0.1 11.5770186335404 0.0831159760666995 0.259012576579947 GO:0031957 very long-chain fatty acid-CoA ligase activity 1/161 10/18639 0.1 11.5770186335404 0.0831159760666995 0.259012576579947 GO:0043121 neurotrophin binding 1/161 10/18639 0.1 11.5770186335404 0.0831159760666995 0.259012576579947 GO:0043208 glycosphingolipid binding 1/161 10/18639 0.1 11.5770186335404 0.0831159760666995 0.259012576579947 GO:0047429 nucleoside triphosphate diphosphatase activity 1/161 10/18639 0.1 11.5770186335404 0.0831159760666995 0.259012576579947 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 1/161 10/18639 0.1 11.5770186335404 0.0831159760666995 0.259012576579947 GO:0016504 peptidase activator activity 2/161 57/18639 0.0350877192982456 4.06211180124224 0.0869888166592906 0.259561109096631 GO:0051082 unfolded protein binding 3/161 121/18639 0.0247933884297521 2.87033519839844 0.0873948873887201 0.259561109096631 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 2/161 58/18639 0.0344827586206897 3.99207539087599 0.0896028493188336 0.259561109096631 GO:0000099 sulfur amino acid transmembrane transporter activity 1/161 11/18639 0.0909090909090909 10.5245623941276 0.0910400905040422 0.259561109096631 GO:0008199 ferric iron binding 1/161 11/18639 0.0909090909090909 10.5245623941276 0.0910400905040422 0.259561109096631 GO:0015173 aromatic amino acid transmembrane transporter activity 1/161 11/18639 0.0909090909090909 10.5245623941276 0.0910400905040422 0.259561109096631 GO:0019215 intermediate filament binding 1/161 11/18639 0.0909090909090909 10.5245623941276 0.0910400905040422 0.259561109096631 GO:0032050 clathrin heavy chain binding 1/161 11/18639 0.0909090909090909 10.5245623941276 0.0910400905040422 0.259561109096631 GO:0045294 alpha-catenin binding 1/161 11/18639 0.0909090909090909 10.5245623941276 0.0910400905040422 0.259561109096631 GO:0047676 arachidonate-CoA ligase activity 1/161 11/18639 0.0909090909090909 10.5245623941276 0.0910400905040422 0.259561109096631 GO:0048185 activin binding 1/161 11/18639 0.0909090909090909 10.5245623941276 0.0910400905040422 0.259561109096631 GO:0050998 nitric-oxide synthase binding 1/161 11/18639 0.0909090909090909 10.5245623941276 0.0910400905040422 0.259561109096631 GO:0015026 coreceptor activity 2/161 61/18639 0.0327868852459016 3.79574381427553 0.097581198795073 0.261554272868071 GO:0004859 phospholipase inhibitor activity 1/161 12/18639 0.0833333333333333 9.64751552795031 0.0988961429749919 0.261554272868071 GO:0005025 transforming growth factor beta receptor activity, type I 1/161 12/18639 0.0833333333333333 9.64751552795031 0.0988961429749919 0.261554272868071 GO:0005026 transforming growth factor beta receptor activity, type II 1/161 12/18639 0.0833333333333333 9.64751552795031 0.0988961429749919 0.261554272868071 GO:0005049 nuclear export signal receptor activity 1/161 12/18639 0.0833333333333333 9.64751552795031 0.0988961429749919 0.261554272868071 GO:0005527 macrolide binding 1/161 12/18639 0.0833333333333333 9.64751552795031 0.0988961429749919 0.261554272868071 GO:0016208 AMP binding 1/161 12/18639 0.0833333333333333 9.64751552795031 0.0988961429749919 0.261554272868071 GO:0016361 activin receptor activity, type I 1/161 12/18639 0.0833333333333333 9.64751552795031 0.0988961429749919 0.261554272868071 GO:0016362 activin receptor activity, type II 1/161 12/18639 0.0833333333333333 9.64751552795031 0.0988961429749919 0.261554272868071 GO:0017002 activin receptor activity 1/161 12/18639 0.0833333333333333 9.64751552795031 0.0988961429749919 0.261554272868071 GO:0031543 peptidyl-proline dioxygenase activity 1/161 12/18639 0.0833333333333333 9.64751552795031 0.0988961429749919 0.261554272868071 GO:0005507 copper ion binding 2/161 63/18639 0.0317460317460317 3.67524401064774 0.103007865046146 0.269731164851602 GO:0004465 lipoprotein lipase activity 1/161 13/18639 0.0769230769230769 8.90539894887721 0.106684714456231 0.269731164851602 GO:0017154 semaphorin receptor activity 1/161 13/18639 0.0769230769230769 8.90539894887721 0.106684714456231 0.269731164851602 GO:0019855 calcium channel inhibitor activity 1/161 13/18639 0.0769230769230769 8.90539894887721 0.106684714456231 0.269731164851602 GO:0031994 insulin-like growth factor I binding 1/161 13/18639 0.0769230769230769 8.90539894887721 0.106684714456231 0.269731164851602 GO:0046974 histone H3K9 methyltransferase activity 1/161 13/18639 0.0769230769230769 8.90539894887721 0.106684714456231 0.269731164851602 GO:0070123 transforming growth factor beta receptor activity, type III 1/161 13/18639 0.0769230769230769 8.90539894887721 0.106684714456231 0.269731164851602 GO:0008195 phosphatidate phosphatase activity 1/161 14/18639 0.0714285714285714 8.26929902395741 0.11440638099615 0.278735546426984 GO:0019763 immunoglobulin receptor activity 1/161 14/18639 0.0714285714285714 8.26929902395741 0.11440638099615 0.278735546426984 GO:0030283 testosterone dehydrogenase [NAD(P)+] activity 1/161 14/18639 0.0714285714285714 8.26929902395741 0.11440638099615 0.278735546426984 GO:0061783 peptidoglycan muralytic activity 1/161 14/18639 0.0714285714285714 8.26929902395741 0.11440638099615 0.278735546426984 GO:0070742 C2H2 zinc finger domain binding 1/161 14/18639 0.0714285714285714 8.26929902395741 0.11440638099615 0.278735546426984 GO:0098821 BMP receptor activity 1/161 14/18639 0.0714285714285714 8.26929902395741 0.11440638099615 0.278735546426984 GO:0030145 manganese ion binding 2/161 68/18639 0.0294117647058824 3.40500548045305 0.116919315788756 0.28314195751253 GO:0004713 protein tyrosine kinase activity 3/161 140/18639 0.0214285714285714 2.48078970718722 0.121122991687738 0.288640052529835 GO:0004467 long-chain fatty acid-CoA ligase activity 1/161 15/18639 0.0666666666666667 7.71801242236025 0.122061713756398 0.288640052529835 GO:0008242 omega peptidase activity 1/161 15/18639 0.0666666666666667 7.71801242236025 0.122061713756398 0.288640052529835 GO:0015929 hexosaminidase activity 1/161 15/18639 0.0666666666666667 7.71801242236025 0.122061713756398 0.288640052529835 GO:0005324 long-chain fatty acid transmembrane transporter activity 1/161 16/18639 0.0625 7.23563664596273 0.12965127905307 0.297827509596195 GO:0005521 lamin binding 1/161 16/18639 0.0625 7.23563664596273 0.12965127905307 0.297827509596195 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 1/161 16/18639 0.0625 7.23563664596273 0.12965127905307 0.297827509596195 GO:0055102 lipase inhibitor activity 1/161 16/18639 0.0625 7.23563664596273 0.12965127905307 0.297827509596195 GO:0070411 I-SMAD binding 1/161 16/18639 0.0625 7.23563664596273 0.12965127905307 0.297827509596195 GO:0048029 monosaccharide binding 2/161 74/18639 0.027027027027027 3.12892395501091 0.134188243729287 0.299698949107714 GO:0003725 double-stranded RNA binding 2/161 75/18639 0.0266666666666667 3.0872049689441 0.137120427801705 0.299698949107714 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/161 17/18639 0.0588235294117647 6.8100109609061 0.137175638397561 0.299698949107714 GO:0019198 transmembrane receptor protein phosphatase activity 1/161 17/18639 0.0588235294117647 6.8100109609061 0.137175638397561 0.299698949107714 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 1/161 17/18639 0.0588235294117647 6.8100109609061 0.137175638397561 0.299698949107714 GO:0038191 neuropilin binding 1/161 17/18639 0.0588235294117647 6.8100109609061 0.137175638397561 0.299698949107714 GO:0048038 quinone binding 1/161 17/18639 0.0588235294117647 6.8100109609061 0.137175638397561 0.299698949107714 GO:0070492 oligosaccharide binding 1/161 17/18639 0.0588235294117647 6.8100109609061 0.137175638397561 0.299698949107714 GO:1990226 histone methyltransferase binding 1/161 17/18639 0.0588235294117647 6.8100109609061 0.137175638397561 0.299698949107714 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1/161 18/18639 0.0555555555555556 6.43167701863354 0.144635348537073 0.31130293334438 GO:1990381 ubiquitin-specific protease binding 1/161 18/18639 0.0555555555555556 6.43167701863354 0.144635348537073 0.31130293334438 GO:0005125 cytokine activity 4/161 234/18639 0.0170940170940171 1.97897754419494 0.14481007098358 0.31130293334438 GO:0004303 estradiol 17-beta-dehydrogenase [NAD(P)+] activity 1/161 19/18639 0.0526315789473684 6.09316770186335 0.152030961494784 0.316665526015042 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/161 19/18639 0.0526315789473684 6.09316770186335 0.152030961494784 0.316665526015042 GO:0005520 insulin-like growth factor binding 1/161 19/18639 0.0526315789473684 6.09316770186335 0.152030961494784 0.316665526015042 GO:0015245 fatty acid transmembrane transporter activity 1/161 19/18639 0.0526315789473684 6.09316770186335 0.152030961494784 0.316665526015042 GO:0042577 lipid phosphatase activity 1/161 19/18639 0.0526315789473684 6.09316770186335 0.152030961494784 0.316665526015042 GO:0097001 ceramide binding 1/161 19/18639 0.0526315789473684 6.09316770186335 0.152030961494784 0.316665526015042 GO:0001618 virus receptor activity 2/161 81/18639 0.0246913580246914 2.85852311939268 0.154995279475977 0.32117578530589 GO:0140272 exogenous protein binding 2/161 82/18639 0.024390243902439 2.82366308135131 0.158017249266602 0.325758636949611 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 1/161 20/18639 0.05 5.78850931677019 0.159363024609679 0.326856815781075 GO:0001846 opsonin binding 1/161 21/18639 0.0476190476190476 5.51286601597161 0.166632080576049 0.340030946150109 GO:0008970 phospholipase A1 activity 1/161 22/18639 0.0454545454545455 5.26228119706381 0.173838667482658 0.352945173373881 GO:0004197 cysteine-type endopeptidase activity 2/161 88/18639 0.0227272727272727 2.6311405985319 0.176367826344973 0.354499330953395 GO:0016651 oxidoreductase activity, acting on NAD(P)H 2/161 88/18639 0.0227272727272727 2.6311405985319 0.176367826344973 0.354499330953395 GO:0005158 insulin receptor binding 1/161 23/18639 0.0434782608695652 5.03348636240886 0.180983318851584 0.358400463932693 GO:0005212 structural constituent of eye lens 1/161 23/18639 0.0434782608695652 5.03348636240886 0.180983318851584 0.358400463932693 GO:0140103 catalytic activity, acting on a glycoprotein 1/161 23/18639 0.0434782608695652 5.03348636240886 0.180983318851584 0.358400463932693 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 2/161 91/18639 0.021978021978022 2.5443996996792 0.185665967301612 0.365871170859059 GO:0004806 triacylglycerol lipase activity 1/161 24/18639 0.0416666666666667 4.82375776397516 0.188066563676729 0.367003682514781 GO:0030215 semaphorin receptor binding 1/161 24/18639 0.0416666666666667 4.82375776397516 0.188066563676729 0.367003682514781 GO:0001848 complement binding 1/161 25/18639 0.04 4.63080745341615 0.195088926462012 0.371686011553217 GO:0005537 D-mannose binding 1/161 25/18639 0.04 4.63080745341615 0.195088926462012 0.371686011553217 GO:0015662 P-type ion transporter activity 1/161 25/18639 0.04 4.63080745341615 0.195088926462012 0.371686011553217 GO:0120020 cholesterol transfer activity 1/161 25/18639 0.04 4.63080745341615 0.195088926462012 0.371686011553217 GO:0140358 P-type transmembrane transporter activity 1/161 25/18639 0.04 4.63080745341615 0.195088926462012 0.371686011553217 GO:0005112 Notch binding 1/161 26/18639 0.0384615384615385 4.45269947443861 0.202050927259241 0.377788245387045 GO:0008198 ferrous iron binding 1/161 26/18639 0.0384615384615385 4.45269947443861 0.202050927259241 0.377788245387045 GO:0050681 nuclear androgen receptor binding 1/161 26/18639 0.0384615384615385 4.45269947443861 0.202050927259241 0.377788245387045 GO:0070006 metalloaminopeptidase activity 1/161 26/18639 0.0384615384615385 4.45269947443861 0.202050927259241 0.377788245387045 GO:0022804 active transmembrane transporter activity 6/161 457/18639 0.0131291028446389 1.51995868274053 0.203954093261153 0.379581229124923 GO:0008266 poly(U) RNA binding 1/161 27/18639 0.037037037037037 4.28778467908903 0.208953081705663 0.387092805740446 GO:0008237 metallopeptidase activity 3/161 184/18639 0.016304347826087 1.88755738590332 0.212890910308078 0.392533720482377 GO:0015078 proton transmembrane transporter activity 3/161 185/18639 0.0162162162162162 1.87735437300655 0.215135266622991 0.392533720482377 GO:0045499 chemorepellent activity 1/161 28/18639 0.0357142857142857 4.1346495119787 0.215795901061207 0.392533720482377 GO:0046625 sphingolipid binding 1/161 28/18639 0.0357142857142857 4.1346495119787 0.215795901061207 0.392533720482377 GO:0008234 cysteine-type peptidase activity 3/161 187/18639 0.0160427807486631 1.85727571661076 0.21963916537202 0.394172320187902 GO:0008238 exopeptidase activity 2/161 102/18639 0.0196078431372549 2.27000365363537 0.220272714785681 0.394172320187902 GO:0046943 carboxylic acid transmembrane transporter activity 3/161 188/18639 0.0159574468085106 1.84739659045857 0.221898464533076 0.394172320187902 GO:0003785 actin monomer binding 1/161 29/18639 0.0344827586206897 3.99207539087599 0.222579892245407 0.394172320187902 GO:0035250 UDP-galactosyltransferase activity 1/161 29/18639 0.0344827586206897 3.99207539087599 0.222579892245407 0.394172320187902 GO:0051861 glycolipid binding 1/161 29/18639 0.0344827586206897 3.99207539087599 0.222579892245407 0.394172320187902 GO:0005342 organic acid transmembrane transporter activity 3/161 189/18639 0.0158730158730159 1.83762200532387 0.224162502323376 0.395233885675426 GO:0008187 poly-pyrimidine tract binding 1/161 30/18639 0.0333333333333333 3.85900621118012 0.229305557874021 0.400786235936332 GO:0031210 phosphatidylcholine binding 1/161 30/18639 0.0333333333333333 3.85900621118012 0.229305557874021 0.400786235936332 GO:0005310 dicarboxylic acid transmembrane transporter activity 1/161 31/18639 0.032258064516129 3.73452213985173 0.235973396295337 0.407130065711268 GO:0005452 solute:inorganic anion antiporter activity 1/161 31/18639 0.032258064516129 3.73452213985173 0.235973396295337 0.407130065711268 GO:0017147 Wnt-protein binding 1/161 31/18639 0.032258064516129 3.73452213985173 0.235973396295337 0.407130065711268 GO:0008378 galactosyltransferase activity 1/161 32/18639 0.03125 3.61781832298137 0.242583901626187 0.409742556528265 GO:0015106 bicarbonate transmembrane transporter activity 1/161 32/18639 0.03125 3.61781832298137 0.242583901626187 0.409742556528265 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/161 32/18639 0.03125 3.61781832298137 0.242583901626187 0.409742556528265 GO:0120015 sterol transfer activity 1/161 32/18639 0.03125 3.61781832298137 0.242583901626187 0.409742556528265 GO:0140142 nucleocytoplasmic carrier activity 1/161 32/18639 0.03125 3.61781832298137 0.242583901626187 0.409742556528265 GO:0004222 metalloendopeptidase activity 2/161 110/18639 0.0181818181818182 2.10491247882552 0.245766063041033 0.413380574654793 GO:0019956 chemokine binding 1/161 33/18639 0.0303030303030303 3.5081874647092 0.249137563787641 0.417305419344299 GO:0005200 structural constituent of cytoskeleton 2/161 112/18639 0.0178571428571429 2.06732475598935 0.252161375665978 0.420617730363996 GO:0015020 glucuronosyltransferase activity 1/161 34/18639 0.0294117647058824 3.40500548045305 0.25563486854042 0.422902128202669 GO:0051427 hormone receptor binding 1/161 34/18639 0.0294117647058824 3.40500548045305 0.25563486854042 0.422902128202669 GO:0001221 transcription coregulator binding 2/161 115/18639 0.0173913043478261 2.01339454496354 0.261762101406575 0.426537131996104 GO:0017124 SH3 domain binding 2/161 115/18639 0.0173913043478261 2.01339454496354 0.261762101406575 0.426537131996104 GO:0005154 epidermal growth factor receptor binding 1/161 35/18639 0.0285714285714286 3.30771960958296 0.262076297519995 0.426537131996104 GO:0016229 steroid dehydrogenase activity 1/161 35/18639 0.0285714285714286 3.30771960958296 0.262076297519995 0.426537131996104 GO:0031625 ubiquitin protein ligase binding 4/161 302/18639 0.0132450331125828 1.5333799514623 0.264779435808488 0.428261333194863 GO:0004190 aspartic-type endopeptidase activity 1/161 36/18639 0.0277777777777778 3.21583850931677 0.268462328271407 0.428261333194863 GO:0140838 RNA polymerase II CTD heptapeptide repeat peptidyl-prolyl isomerase activity 1/161 36/18639 0.0277777777777778 3.21583850931677 0.268462328271407 0.428261333194863 GO:0140839 RNA polymerase II CTD heptapeptide repeat P3 isomerase activity 1/161 36/18639 0.0277777777777778 3.21583850931677 0.268462328271407 0.428261333194863 GO:0140840 RNA polymerase II CTD heptapeptide repeat P6 isomerase activity 1/161 36/18639 0.0277777777777778 3.21583850931677 0.268462328271407 0.428261333194863 GO:0070001 aspartic-type peptidase activity 1/161 37/18639 0.027027027027027 3.12892395501091 0.274793434283787 0.436628302695978 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/161 39/18639 0.0256410256410256 2.9684663162924 0.287292745973514 0.454691668824223 GO:0004177 aminopeptidase activity 1/161 40/18639 0.025 2.89425465838509 0.293461878656216 0.455489093512737 GO:0030331 nuclear estrogen receptor binding 1/161 40/18639 0.025 2.89425465838509 0.293461878656216 0.455489093512737 GO:0050997 quaternary ammonium group binding 1/161 40/18639 0.025 2.89425465838509 0.293461878656216 0.455489093512737 GO:0071855 neuropeptide receptor binding 1/161 40/18639 0.025 2.89425465838509 0.293461878656216 0.455489093512737 GO:0071949 FAD binding 1/161 40/18639 0.025 2.89425465838509 0.293461878656216 0.455489093512737 GO:0015175 neutral L-amino acid transmembrane transporter activity 1/161 41/18639 0.024390243902439 2.82366308135131 0.299577940677634 0.458462078632665 GO:0042287 MHC protein binding 1/161 41/18639 0.024390243902439 2.82366308135131 0.299577940677634 0.458462078632665 GO:0140318 protein transporter activity 1/161 41/18639 0.024390243902439 2.82366308135131 0.299577940677634 0.458462078632665 GO:0044389 ubiquitin-like protein ligase binding 4/161 322/18639 0.0124223602484472 1.43813896068825 0.30325881290349 0.458462078632665 GO:0016859 cis-trans isomerase activity 1/161 42/18639 0.0238095238095238 2.7564330079858 0.30564138575511 0.458462078632665 GO:0019894 kinesin binding 1/161 42/18639 0.0238095238095238 2.7564330079858 0.30564138575511 0.458462078632665 GO:0035198 miRNA binding 1/161 42/18639 0.0238095238095238 2.7564330079858 0.30564138575511 0.458462078632665 GO:0042056 chemoattractant activity 1/161 42/18639 0.0238095238095238 2.7564330079858 0.30564138575511 0.458462078632665 GO:0048487 beta-tubulin binding 1/161 42/18639 0.0238095238095238 2.7564330079858 0.30564138575511 0.458462078632665 GO:0016798 hydrolase activity, acting on glycosyl bonds 2/161 130/18639 0.0153846153846154 1.78107978977544 0.309690516201707 0.46230395139478 GO:0008200 ion channel inhibitor activity 1/161 43/18639 0.0232558139534884 2.69232991477683 0.311652663751208 0.46230395139478 GO:0048156 tau protein binding 1/161 43/18639 0.0232558139534884 2.69232991477683 0.311652663751208 0.46230395139478 GO:0016248 channel inhibitor activity 1/161 44/18639 0.0227272727272727 2.6311405985319 0.317612220706255 0.467692720600419 GO:0043014 alpha-tubulin binding 1/161 44/18639 0.0227272727272727 2.6311405985319 0.317612220706255 0.467692720600419 GO:0046915 transition metal ion transmembrane transporter activity 1/161 45/18639 0.0222222222222222 2.57267080745342 0.323520498870616 0.472928147439955 GO:0141110 transporter inhibitor activity 1/161 45/18639 0.0222222222222222 2.57267080745342 0.323520498870616 0.472928147439955 GO:0016779 nucleotidyltransferase activity 2/161 136/18639 0.0147058823529412 1.70250274022653 0.328719241946528 0.478014189776716 GO:0030291 protein serine/threonine kinase inhibitor activity 1/161 46/18639 0.0217391304347826 2.51674318120443 0.329377936736693 0.478014189776716 GO:0016922 nuclear receptor binding 2/161 137/18639 0.0145985401459854 1.6900757129256 0.331877878358054 0.47990973776956 GO:0043495 protein-membrane adaptor activity 1/161 47/18639 0.0212765957446809 2.46319545394476 0.335184969070657 0.480386635504098 GO:0140938 histone H3 methyltransferase activity 1/161 47/18639 0.0212765957446809 2.46319545394476 0.335184969070657 0.480386635504098 GO:0003779 actin binding 5/161 443/18639 0.0112866817155756 1.30666124532058 0.336731124420067 0.480386635504098 GO:0030295 protein kinase activator activity 2/161 139/18639 0.0143884892086331 1.6657580767684 0.33818263146184 0.480386635504098 GO:0070851 growth factor receptor binding 2/161 139/18639 0.0143884892086331 1.6657580767684 0.33818263146184 0.480386635504098 GO:0038187 pattern recognition receptor activity 1/161 48/18639 0.0208333333333333 2.41187888198758 0.340942026943915 0.482601038138922 GO:0005006 epidermal growth factor receptor activity 1/161 50/18639 0.02 2.31540372670807 0.352307925307076 0.496939599906823 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 4/161 349/18639 0.0114613180515759 1.32687892648027 0.356056514092457 0.497864633625205 GO:0003743 translation initiation factor activity 1/161 51/18639 0.0196078431372549 2.27000365363537 0.357917609745483 0.497864633625205 GO:0005010 insulin-like growth factor receptor activity 1/161 51/18639 0.0196078431372549 2.27000365363537 0.357917609745483 0.497864633625205 GO:0005021 vascular endothelial growth factor receptor activity 1/161 51/18639 0.0196078431372549 2.27000365363537 0.357917609745483 0.497864633625205 GO:0019209 kinase activator activity 2/161 148/18639 0.0135135135135135 1.56446197750546 0.366316485584913 0.507790438638397 GO:0004864 protein phosphatase inhibitor activity 1/161 53/18639 0.0188679245283019 2.18434313840384 0.368992532174942 0.507996568268243 GO:0005246 calcium channel regulator activity 1/161 53/18639 0.0188679245283019 2.18434313840384 0.368992532174942 0.507996568268243 GO:0019829 ATPase-coupled monoatomic cation transmembrane transporter activity 1/161 54/18639 0.0185185185185185 2.14389233954451 0.374458592775385 0.512014810529609 GO:0051287 NAD binding 1/161 54/18639 0.0185185185185185 2.14389233954451 0.374458592775385 0.512014810529609 GO:0019887 protein kinase regulator activity 3/161 255/18639 0.0117647058823529 1.36200219218122 0.378585825865584 0.515599014347609 GO:0098632 cell-cell adhesion mediator activity 1/161 55/18639 0.0181818181818182 2.10491247882552 0.379877595549836 0.515599014347609 GO:0003713 transcription coactivator activity 3/161 256/18639 0.01171875 1.35668187111801 0.380927630003085 0.515599014347609 GO:0005506 iron ion binding 2/161 154/18639 0.012987012987013 1.5035089134468 0.384819918259036 0.51623492377161 GO:0019212 phosphatase inhibitor activity 1/161 56/18639 0.0178571428571429 2.06732475598935 0.385249943113142 0.51623492377161 GO:0170055 lipid transmembrane transporter activity 1/161 56/18639 0.0178571428571429 2.06732475598935 0.385249943113142 0.51623492377161 GO:0004601 peroxidase activity 1/161 57/18639 0.0175438596491228 2.03105590062112 0.39057603465696 0.521633109408964 GO:0061980 regulatory RNA binding 1/161 58/18639 0.0172413793103448 1.996037695438 0.395856265978682 0.526934499746458 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1/161 59/18639 0.0169491525423729 1.96220654805769 0.401091029510108 0.53214057380549 GO:0016706 2-oxoglutarate-dependent dioxygenase activity 1/161 60/18639 0.0166666666666667 1.92950310559006 0.406280714345893 0.537252786733713 GO:0008514 organic anion transmembrane transporter activity 3/161 269/18639 0.0111524163568773 1.29111731972569 0.411177824120398 0.540500437651109 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/161 61/18639 0.0163934426229508 1.89787190713777 0.411425706271739 0.540500437651109 GO:0015179 L-amino acid transmembrane transporter activity 1/161 62/18639 0.0161290322580645 1.86726106992587 0.416526387792369 0.545418918216717 GO:0015103 inorganic anion transmembrane transporter activity 2/161 165/18639 0.0121212121212121 1.40327498588368 0.418117518568243 0.545724813196214 GO:0016874 ligase activity 2/161 167/18639 0.0119760479041916 1.38646929742998 0.424075872531483 0.551710358439017 GO:0005543 phospholipid binding 5/161 497/18639 0.0100603621730382 1.16469000337428 0.42919182370497 0.556564881062574 GO:0120013 lipid transfer activity 1/161 65/18639 0.0153846153846154 1.78107978977544 0.431566346336042 0.557844602016363 GO:0008235 metalloexopeptidase activity 1/161 66/18639 0.0151515151515152 1.7540937323546 0.436493546628919 0.562405146618031 GO:0016500 protein-hormone receptor activity 1/161 67/18639 0.0149253731343284 1.72791322888662 0.441378300787792 0.565076678078638 GO:0042054 histone methyltransferase activity 1/161 67/18639 0.0149253731343284 1.72791322888662 0.441378300787792 0.565076678078638 GO:0002039 p53 binding 1/161 69/18639 0.0144927536231884 1.67782878746962 0.451021921183927 0.573187385749043 GO:0016279 protein-lysine N-methyltransferase activity 1/161 69/18639 0.0144927536231884 1.67782878746962 0.451021921183927 0.573187385749043 GO:0019207 kinase regulator activity 3/161 287/18639 0.0104529616724739 1.21014132057913 0.452280040695259 0.573187385749043 GO:0008028 monocarboxylic acid transmembrane transporter activity 1/161 70/18639 0.0142857142857143 1.65385980479148 0.455781504958262 0.573187385749043 GO:0016278 lysine N-methyltransferase activity 1/161 70/18639 0.0142857142857143 1.65385980479148 0.455781504958262 0.573187385749043 GO:0005319 lipid transporter activity 2/161 178/18639 0.0112359550561798 1.30078861051015 0.456268565770382 0.573187385749043 GO:0004521 RNA endonuclease activity 1/161 73/18639 0.0136986301369863 1.58589296349868 0.469815591974601 0.586539962651521 GO:0043539 protein serine/threonine kinase activator activity 1/161 73/18639 0.0136986301369863 1.58589296349868 0.469815591974601 0.586539962651521 GO:0031491 nucleosome binding 1/161 74/18639 0.0135135135135135 1.56446197750546 0.474413226882072 0.588623818538867 GO:0035064 methylated histone binding 1/161 74/18639 0.0135135135135135 1.56446197750546 0.474413226882072 0.588623818538867 GO:0140034 methylation-dependent protein binding 1/161 76/18639 0.0131578947368421 1.52329192546584 0.483489963748837 0.598039893621638 GO:0015370 solute:sodium symporter activity 1/161 79/18639 0.0126582278481013 1.46544539665068 0.496813784181565 0.612635402579721 GO:0015101 organic cation transmembrane transporter activity 1/161 81/18639 0.0123456790123457 1.42926155969634 0.505506000566145 0.62144774381526 GO:0008135 translation factor activity, RNA binding 1/161 83/18639 0.0120481927710843 1.3948215221133 0.514048981129549 0.628108481501759 GO:0030165 PDZ domain binding 1/161 83/18639 0.0120481927710843 1.3948215221133 0.514048981129549 0.628108481501759 GO:0004860 protein kinase inhibitor activity 1/161 84/18639 0.0119047619047619 1.3782165039929 0.51826530544719 0.629433996343717 GO:0180051 translation factor activity 1/161 84/18639 0.0119047619047619 1.3782165039929 0.51826530544719 0.629433996343717 GO:0050660 flavin adenine dinucleotide binding 1/161 86/18639 0.0116279069767442 1.34616495738842 0.526589193396326 0.637617035377479 GO:0005516 calmodulin binding 2/161 207/18639 0.00966183574879227 1.11855252497975 0.535921274123752 0.643686856450957 GO:0003727 single-stranded RNA binding 1/161 89/18639 0.0112359550561798 1.30078861051015 0.538807757456264 0.643686856450957 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 1/161 89/18639 0.0112359550561798 1.30078861051015 0.538807757456264 0.643686856450957 GO:0030946 protein tyrosine phosphatase activity, metal-dependent 1/161 89/18639 0.0112359550561798 1.30078861051015 0.538807757456264 0.643686856450957 GO:0051015 actin filament binding 2/161 209/18639 0.00956937799043062 1.10784867306606 0.541115131314747 0.643686856450957 GO:0019210 kinase inhibitor activity 1/161 90/18639 0.0111111111111111 1.28633540372671 0.542810558051927 0.643686856450957 GO:0140793 histone H2AXY142 phosphatase activity 1/161 90/18639 0.0111111111111111 1.28633540372671 0.542810558051927 0.643686856450957 GO:0045296 cadherin binding 3/161 334/18639 0.00898203592814371 1.03985197307249 0.553307690769814 0.653825269132122 GO:0051213 dioxygenase activity 1/161 93/18639 0.010752688172043 1.24484071328391 0.554612977049885 0.653825269132122 GO:0008276 protein methyltransferase activity 1/161 95/18639 0.0105263157894737 1.21863354037267 0.562312532475237 0.660963853962121 GO:0004725 protein tyrosine phosphatase activity 1/161 98/18639 0.0102040816326531 1.18132843199392 0.573614525031236 0.668385620471179 GO:0008170 N-methyltransferase activity 1/161 98/18639 0.0102040816326531 1.18132843199392 0.573614525031236 0.668385620471179 GO:0042626 ATPase-coupled transmembrane transporter activity 1/161 98/18639 0.0102040816326531 1.18132843199392 0.573614525031236 0.668385620471179 GO:0043130 ubiquitin binding 1/161 100/18639 0.01 1.15770186335404 0.580987573459584 0.675020244308534 GO:0015171 amino acid transmembrane transporter activity 1/161 102/18639 0.00980392156862745 1.13500182681768 0.588233905560978 0.68146982719168 GO:0019888 protein phosphatase regulator activity 1/161 107/18639 0.00934579439252336 1.0819643582748 0.605809465636439 0.699814382717955 GO:0005496 steroid binding 1/161 108/18639 0.00925925925925926 1.07194616977226 0.609234065033834 0.701643579829957 GO:0140297 DNA-binding transcription factor binding 4/161 488/18639 0.00819672131147541 0.948935953568883 0.611352084131797 0.701643579829957 GO:0004620 phospholipase activity 1/161 109/18639 0.00917431192660551 1.06211180124224 0.612629095821679 0.701643579829957 GO:0015294 solute:monoatomic cation symporter activity 1/161 116/18639 0.00862068965517241 0.998018847718998 0.635587432341857 0.725869738072234 GO:0019208 phosphatase regulator activity 1/161 117/18639 0.00854700854700855 0.989488772097468 0.638754868685482 0.727420558672985 GO:0032182 ubiquitin-like protein binding 1/161 120/18639 0.00833333333333333 0.964751552795031 0.648093946253783 0.730508030247052 GO:0015631 tubulin binding 3/161 385/18639 0.00779220779220779 0.902105348068081 0.649565957768441 0.730508030247052 GO:0004540 RNA nuclease activity 1/161 121/18639 0.00826446280991736 0.956778399466147 0.651153337940868 0.730508030247052 GO:0015108 chloride transmembrane transporter activity 1/161 121/18639 0.00826446280991736 0.956778399466147 0.651153337940868 0.730508030247052 GO:0140098 catalytic activity, acting on RNA 3/161 387/18639 0.00775193798449612 0.89744330492561 0.653026653884946 0.730508030247052 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1/161 122/18639 0.00819672131147541 0.948935953568883 0.654186295743629 0.730508030247052 GO:1990756 ubiquitin-like ligase-substrate adaptor activity 1/161 122/18639 0.00819672131147541 0.948935953568883 0.654186295743629 0.730508030247052 GO:0004519 endonuclease activity 1/161 127/18639 0.0078740157480315 0.91157627035751 0.668962453344527 0.744938798461218 GO:0140994 RNA polymerase II CTD heptapeptide repeat modifying activity 1/161 128/18639 0.0078125 0.904454580745342 0.671841507202108 0.746078137832175 GO:0016298 lipase activity 1/161 130/18639 0.00769230769230769 0.890539894887721 0.677525173293239 0.750317134060281 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 1/161 132/18639 0.00757575757575758 0.877046866177301 0.683110999857668 0.754017059966707 GO:0016791 phosphatase activity 2/161 273/18639 0.00732600732600733 0.848133233226401 0.685869565037113 0.754017059966707 GO:0005126 cytokine receptor binding 2/161 275/18639 0.00727272727272727 0.841964991530209 0.689730007262828 0.754017059966707 GO:0015297 antiporter activity 1/161 135/18639 0.00740740740740741 0.857556935817805 0.691309944406634 0.754017059966707 GO:0008017 microtubule binding 2/161 276/18639 0.0072463768115942 0.83891439373481 0.691645660836217 0.754017059966707 GO:0044325 transmembrane transporter binding 1/161 136/18639 0.00735294117647059 0.851251370113263 0.693995801461894 0.754017059966707 GO:0140789 histone phosphatase activity 1/161 136/18639 0.00735294117647059 0.851251370113263 0.693995801461894 0.754017059966707 GO:0140767 enzyme-substrate adaptor activity 1/161 139/18639 0.00719424460431655 0.8328790383842 0.701914817677501 0.760565381957831 GO:0015291 secondary active transmembrane transporter activity 2/161 287/18639 0.00696864111498258 0.806760880386089 0.712084120933085 0.769510259718011 GO:0019903 protein phosphatase binding 1/161 144/18639 0.00694444444444444 0.803959627329193 0.714663100884437 0.770226719988052 GO:0015293 symporter activity 1/161 146/18639 0.00684931506849315 0.792946481749341 0.719609358806191 0.773483856256922 GO:0015085 calcium ion transmembrane transporter activity 1/161 147/18639 0.00680272108843537 0.787552287995944 0.722050438849029 0.774038070446159 GO:0008509 monoatomic anion transmembrane transporter activity 1/161 149/18639 0.00671140939597315 0.776981116344991 0.726869417019726 0.777131663941303 GO:0046873 metal ion transmembrane transporter activity 3/161 450/18639 0.00666666666666667 0.771801242236025 0.749695166473413 0.799409700059183 GO:0099106 ion channel regulator activity 1/161 160/18639 0.00625 0.723563664596273 0.75192703318651 0.799668432118987 GO:0015081 sodium ion transmembrane transporter activity 1/161 164/18639 0.00609756097560976 0.705915770337828 0.760460820329069 0.806610157710517 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 1/161 167/18639 0.00598802395209581 0.693234648714992 0.766669116082137 0.811055222802682 GO:0016247 channel regulator activity 1/161 168/18639 0.00595238095238095 0.689108251996451 0.768702803409485 0.811072249266701 GO:0141108 transporter regulator activity 1/161 170/18639 0.00588235294117647 0.68100109609061 0.772717480929222 0.813173893543317 GO:0140030 modification-dependent protein binding 1/161 173/18639 0.00578034682080925 0.669191828528345 0.778610009735462 0.817235571576125 GO:0004721 phosphoprotein phosphatase activity 1/161 175/18639 0.00571428571428571 0.661543921916593 0.782453761600642 0.819131281675672 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1/161 181/18639 0.00552486187845304 0.639614289145877 0.793591582791656 0.828633289044794 GO:1901981 phosphatidylinositol phosphate binding 1/161 185/18639 0.00540540540540541 0.625784791002182 0.80070006965701 0.833889709850046 GO:0003712 transcription coregulator activity 3/161 495/18639 0.00606060606060606 0.701637492941841 0.804700437022976 0.835890376442472 GO:0019902 phosphatase binding 1/161 190/18639 0.00526315789473684 0.609316770186335 0.809244457339223 0.838443999614349 GO:0042578 phosphoric ester hydrolase activity 2/161 363/18639 0.00550964187327824 0.637852266310764 0.824303348565766 0.850648746959466 GO:0016829 lyase activity 1/161 200/18639 0.005 0.578850931677019 0.825256247050228 0.850648746959466 GO:0008168 methyltransferase activity 1/161 204/18639 0.00490196078431373 0.567500913408842 0.8312803567212 0.854666760618728 GO:0004518 nuclease activity 1/161 209/18639 0.00478468899521531 0.553924336533032 0.838521031782593 0.859911874430108 GO:0016741 transferase activity, transferring one-carbon groups 1/161 215/18639 0.00465116279069767 0.538465982955366 0.84680327061417 0.866195711925945 GO:0042393 histone binding 1/161 247/18639 0.00404858299595142 0.468705207835643 0.884343906884429 0.902067605708117 GO:0140104 molecular carrier activity 1/161 249/18639 0.00401606425702811 0.464940507371099 0.886359960832602 0.902067605708117 GO:0004674 protein serine/threonine kinase activity 2/161 433/18639 0.0046189376443418 0.534735271757061 0.891299350392194 0.904803886004197 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 1/161 268/18639 0.00373134328358209 0.431978307221656 0.903852746617914 0.915236282469525 GO:0001217 DNA-binding transcription repressor activity 1/161 278/18639 0.00359712230215827 0.4164395191921 0.91195616324265 0.921121551817953 GO:0035091 phosphatidylinositol binding 1/161 284/18639 0.00352112676056338 0.407641501180999 0.916488522962271 0.923379414112364 GO:0001664 G protein-coupled receptor binding 1/161 297/18639 0.00336700336700337 0.389798607189912 0.925528646673016 0.930156289906381 GO:0046982 protein heterodimerization activity 1/161 369/18639 0.002710027100271 0.313740342372368 0.960575199021223 0.962970648395341 GO:0016887 ATP hydrolysis activity 1/161 417/18639 0.00239808153477218 0.277626346128066 0.97423590268306 0.97423590268306