ID Description GeneRatio BgRatio pvalue p.adjust geneID Count GO:0048002 antigen processing and presentation of peptide antigen 12/445 62/18722 2.06649453692591e-08 8.53668893204093e-05 CD74/HLA-B/HLA-DRA/HLA-DRB1/FCER1G/HLA-DPA1/HLA-C/HLA-A/HLA-DPB1/CTSD/CALR/CTSS 12 GO:0002478 antigen processing and presentation of exogenous peptide antigen 9/445 38/18722 1.97476623283034e-07 0.000292250642525416 CD74/HLA-DRA/HLA-DRB1/FCER1G/HLA-DPA1/HLA-A/HLA-DPB1/CTSD/CTSS 9 GO:0007015 actin filament organization 30/445 441/18722 2.70126669254323e-07 0.000292250642525416 TPM1/TMSB4X/MYADM/LIMA1/ARHGEF5/SFRP1/CDC42EP3/PAWR/HAX1/TPM3/DSTN/RHOB/TMOD3/KANK4/GSN/FERMT2/SHTN1/MICAL3/PAK2/MPRIP/AIF1/CAPZA2/GRB2/TJP1/CALD1/PIK3CA/RDX/CTNNA1/RGCC/RHOA 30 GO:0022411 cellular component disassembly 30/445 443/18722 2.97525623260202e-07 0.000292250642525416 LIMA1/DFFB/CCSAP/ATG12/HAX1/GABARAP/DSTN/BNIP3/HSPA2/SMARCB1/TMOD3/RPL23/KIF2A/GOLGA2/GSN/BNIP3L/MICAL3/CHMP5/RB1CC1/C1QB/DENR/CDC37/C1QA/CAPZA2/CST3/PIK3CA/CTSS/RDX/VAMP8/UFC1 30 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 8/445 30/18722 3.53728688604957e-07 0.000292250642525416 CD74/HLA-DRA/HLA-DRB1/FCER1G/HLA-DPA1/HLA-DPB1/CTSD/CTSS 8 GO:0061458 reproductive system development 29/445 427/18722 4.43559285941111e-07 0.000305390568370455 KRT19/STK3/WNT7A/CGA/CEBPB/KRT8/SFRP1/CTNNB1/ING2/SPINT1/SPP1/ANXA1/PHLDA2/INHA/ADAMTS1/FNDC3A/PLEKHA5/TMF1/BASP1/LRP2/HSP90AB1/CBL/SERPINF1/GRB2/PPARG/CTNNA1/NRIP1/GATA3/PSAP 29 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 8/445 34/18722 1.0094430908786e-06 0.000573362521451205 CD74/HLA-DRA/HLA-DRB1/FCER1G/HLA-DPA1/HLA-DPB1/CTSD/CTSS 8 GO:0048608 reproductive structure development 28/445 424/18722 1.22422538390563e-06 0.000573362521451205 KRT19/STK3/WNT7A/CGA/CEBPB/KRT8/SFRP1/CTNNB1/ING2/SPINT1/SPP1/ANXA1/PHLDA2/INHA/ADAMTS1/FNDC3A/TMF1/BASP1/LRP2/HSP90AB1/CBL/SERPINF1/GRB2/PPARG/CTNNA1/NRIP1/GATA3/PSAP 28 GO:0019884 antigen processing and presentation of exogenous antigen 9/445 47/18722 1.36566942917725e-06 0.000573362521451205 CD74/HLA-DRA/HLA-DRB1/FCER1G/HLA-DPA1/HLA-A/HLA-DPB1/CTSD/CTSS 9 GO:0019882 antigen processing and presentation 13/445 106/18722 1.38795091128348e-06 0.000573362521451205 CD74/HLA-B/HLA-DRA/HLA-DRB1/FCER1G/HLA-DPA1/HLA-C/HLA-A/HLA-DPB1/CTSD/CALR/RAB8B/CTSS 13 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 8/445 36/18722 1.61370316314376e-06 0.000606018887904262 CD74/HLA-DRA/HLA-DRB1/FCER1G/HLA-DPA1/HLA-DPB1/CTSD/CTSS 8 GO:0060333 interferon-gamma-mediated signaling pathway 7/445 27/18722 2.40524812293526e-06 0.000828006666320463 SP100/IRF1/HSP90AB1/PARP14/CDC37/JAK1/PPARG 7 GO:0010594 regulation of endothelial cell migration 19/445 232/18722 3.07991954918762e-06 0.000865807233400411 APOE/KLF4/TMSB4X/WNT7A/ANXA1/HMOX1/RHOB/SP100/SASH1/PLK2/PLPP3/SERPINF1/CALR/PPARG/RGCC/RHOA/SPARC/GATA3/PDCD6 19 GO:0110053 regulation of actin filament organization 21/445 277/18722 3.21750871368634e-06 0.000865807233400411 TPM1/TMSB4X/MYADM/LIMA1/ARHGEF5/SFRP1/CDC42EP3/HAX1/DSTN/TMOD3/KANK4/GSN/FERMT2/PAK2/CAPZA2/GRB2/TJP1/PIK3CA/RDX/RGCC/RHOA 21 GO:0006979 response to oxidative stress 28/445 446/18722 3.26351859386295e-06 0.000865807233400411 FOS/TPM1/APOE/KLF4/PAGE4/HBA2/CTNNB1/SLC25A24/ANXA1/LDHA/PAWR/ERO1A/HBA1/MAPKAP1/BNIP3/HMOX1/GSTP1/RHOB/JUN/HNRNPM/NET1/HSPA1B/TXNIP/AIF1/PON2/MCL1/ATF4/HBB 28 GO:0000375 RNA splicing, via transesterification reactions 23/445 324/18722 3.35340492239327e-06 0.000865807233400411 MPHOSPH10/SFSWAP/RBM17/NCL/SRSF4/HNRNPH3/SRSF5/SCAF11/PRPF40A/HNRNPF/HNRNPM/SMNDC1/RBM39/EIF4A3/YTHDC1/SRSF9/HNRNPA1/SF3B2/KHDRBS1/SRRM2/RBM3/HNRNPR/SRSF2 23 GO:0032535 regulation of cellular component size 25/445 382/18722 5.35996536783634e-06 0.00130247158438423 APOE/TMSB4X/MYADM/LIMA1/WNT7A/CDC42EP3/PPP1R15A/SPP1/VAV2/HAX1/SEMA4C/DSTN/TMOD3/KANK4/GSN/SHTN1/GOLGA4/RB1CC1/HSP90AB1/CAPZA2/GRB2/MACF1/PIK3CA/RDX/RHOA 25 GO:0008380 RNA splicing 27/445 434/18722 5.78380079941163e-06 0.00132738228346497 MPHOSPH10/SFSWAP/RBM17/IWS1/NCL/CLK4/SRSF4/HNRNPH3/SRSF5/SCAF11/PRPF40A/HNRNPF/HNRNPM/SMNDC1/RBM39/YBX1/EIF4A3/YTHDC1/SRSF9/HNRNPA1/SF3B2/KHDRBS1/SRRM2/RBM3/HNRNPR/SRSF2/CIR1 27 GO:0001838 embryonic epithelial tube formation 13/445 121/18722 6.19948827825887e-06 0.00134789926723618 MTHFD1L/STK3/LUZP1/SFRP1/CTNNB1/SPINT1/SEMA4C/BRD2/SOX4/LRP2/IRX2/LMO4/GATA3 13 GO:0032970 regulation of actin filament-based process 25/445 396/18722 9.9892420479955e-06 0.00206327794501347 TPM1/TMSB4X/MYADM/LIMA1/ARHGEF5/SFRP1/CDC42EP3/SRI/HAX1/DSTN/RHOB/TMOD3/KANK4/GSN/FERMT2/PKP2/PAK2/CAPZA2/GRB2/TJP1/PIK3CA/RDX/DSP/RGCC/RHOA 25 GO:0035148 tube formation 14/445 148/18722 1.21447637554519e-05 0.00226859403584953 MTHFD1L/STK3/LUZP1/SFRP1/CTNNB1/SPINT1/SEMA4C/BRD2/YWHAZ/SOX4/LRP2/IRX2/LMO4/GATA3 14 GO:0043484 regulation of RNA splicing 14/445 148/18722 1.21447637554519e-05 0.00226859403584953 SFSWAP/NCL/CLK4/SRSF4/HNRNPH3/SRSF5/HNRNPF/RBM39/YTHDC1/SRSF9/HNRNPA1/KHDRBS1/RBM3/SRSF2 14 GO:0043542 endothelial cell migration 20/445 279/18722 1.26307583695326e-05 0.00226859403584953 APOE/KLF4/TMSB4X/WNT7A/ANXA1/HMOX1/RHOB/SP100/SASH1/PLK2/PLPP3/SERPINF1/PIK3CA/CALR/PPARG/RGCC/RHOA/SPARC/GATA3/PDCD6 20 GO:0072175 epithelial tube formation 13/445 132/18722 1.60705980316395e-05 0.00276615168619595 MTHFD1L/STK3/LUZP1/SFRP1/CTNNB1/SPINT1/SEMA4C/BRD2/SOX4/LRP2/IRX2/LMO4/GATA3 13 GO:0000302 response to reactive oxygen species 17/445 222/18722 2.43174749285784e-05 0.00388066631115388 FOS/TPM1/APOE/KLF4/HBA2/ANXA1/LDHA/PAWR/HBA1/BNIP3/HMOX1/GSTP1/RHOB/JUN/NET1/TXNIP/HBB 17 GO:0010632 regulation of epithelial cell migration 20/445 292/18722 2.44244309101914e-05 0.00388066631115388 APOE/KLF4/TMSB4X/WNT7A/ANXA1/HMOX1/RHOB/SP100/SASH1/PLK2/PLPP3/SERPINF1/MACF1/CALR/PPARG/RGCC/RHOA/SPARC/GATA3/PDCD6 20 GO:0019883 antigen processing and presentation of endogenous antigen 6/445 26/18722 2.67984579067254e-05 0.00399542181597492 CD74/HLA-B/HLA-DRA/HLA-DRB1/HLA-C/HLA-A 6 GO:0022407 regulation of cell-cell adhesion 26/445 448/18722 2.86907334826591e-05 0.00399542181597492 KLF4/CD74/MYADM/HLA-DRA/CEBPB/HLA-DRB1/ANXA1/PAWR/SLC7A1/SOX4/HLA-DPA1/WNK1/IRF1/HLA-A/HLA-DPB1/AIF1/PLPP3/TJP1/JAK1/PIK3CA/RDX/RGCC/RHOA/LAPTM5/GATA3/NFKBIZ 26 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 21/445 320/18722 2.90154089758527e-05 0.00399542181597492 SFSWAP/RBM17/NCL/SRSF4/HNRNPH3/SRSF5/SCAF11/PRPF40A/HNRNPF/HNRNPM/RBM39/EIF4A3/YTHDC1/SRSF9/HNRNPA1/SF3B2/KHDRBS1/SRRM2/RBM3/HNRNPR/SRSF2 21 GO:0000398 mRNA splicing, via spliceosome 21/445 320/18722 2.90154089758527e-05 0.00399542181597492 SFSWAP/RBM17/NCL/SRSF4/HNRNPH3/SRSF5/SCAF11/PRPF40A/HNRNPF/HNRNPM/RBM39/EIF4A3/YTHDC1/SRSF9/HNRNPA1/SF3B2/KHDRBS1/SRRM2/RBM3/HNRNPR/SRSF2 21 GO:0007159 leukocyte cell-cell adhesion 23/445 371/18722 3.00262610434573e-05 0.00400124143130716 KLF4/CD74/HLA-DRA/CEBPB/HLA-DRB1/S100A9/ANXA1/PAWR/S100A8/SLC7A1/SOX4/HLA-DPA1/WNK1/IRF1/HLA-A/HLA-DPB1/AIF1/PIK3CA/RHOA/LAPTM5/GOLPH3/GATA3/NFKBIZ 23 GO:0061572 actin filament bundle organization 14/445 161/18722 3.14538672195969e-05 0.00406049767137984 TPM1/LIMA1/ARHGEF5/SFRP1/PAWR/FERMT2/SHTN1/PAK2/AIF1/TJP1/CALD1/RDX/RGCC/RHOA 14 GO:0051235 maintenance of location 21/445 326/18722 3.80832767642964e-05 0.00476733382767601 FTL/APOE/TMSB4X/PLIN2/FBN2/S100A9/SRI/MORC3/GOPC/ERO1A/S100A8/ARHGAP21/TAF3/SP100/GSN/SRGN/HILPDA/CALR/PPARG/NRIP1/GOLPH3 21 GO:0019646 aerobic electron transport chain 10/445 87/18722 4.06210633410247e-05 0.0049354591959345 UQCR10/UQCRQ/COX6C/COX7C/NDUFB2/NDUFA3/COX6A1/NDUFB1/NDUFA4/COX4I1 10 GO:1902105 regulation of leukocyte differentiation 19/445 279/18722 4.20029542191284e-05 0.00495754868226342 FOS/CA2/CD74/HLA-B/HLA-DRA/CEBPB/SFRP1/CTNNB1/HLA-DRB1/TYROBP/ANXA1/HAX1/INHA/JUN/SOX4/IRF1/RHOA/GATA3/NFKBIZ 19 GO:0042542 response to hydrogen peroxide 13/445 146/18722 4.68803770078388e-05 0.00518934210733213 KLF4/HBA2/ANXA1/LDHA/PAWR/HBA1/BNIP3/HMOX1/RHOB/JUN/NET1/TXNIP/HBB 13 GO:1902903 regulation of supramolecular fiber organization 23/445 382/18722 4.71999757026744e-05 0.00518934210733213 TPM1/APOE/TMSB4X/MYADM/LIMA1/ARHGEF5/SFRP1/CDC42EP3/HAX1/DSTN/TMOD3/KANK4/GSN/FERMT2/PAK2/HSPA1B/CAPZA2/GRB2/TJP1/PIK3CA/RDX/RGCC/RHOA 23 GO:0032956 regulation of actin cytoskeleton organization 22/445 357/18722 4.87433080886387e-05 0.00518934210733213 TPM1/TMSB4X/MYADM/LIMA1/ARHGEF5/SFRP1/CDC42EP3/HAX1/DSTN/RHOB/TMOD3/KANK4/GSN/FERMT2/PAK2/CAPZA2/GRB2/TJP1/PIK3CA/RDX/RGCC/RHOA 22 GO:0002501 peptide antigen assembly with MHC protein complex 5/445 18/18722 4.9206183709309e-05 0.00518934210733213 HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/CALR 5 GO:0016331 morphogenesis of embryonic epithelium 13/445 147/18722 5.03384776623388e-05 0.00518934210733213 MTHFD1L/STK3/LUZP1/SFRP1/CTNNB1/SPINT1/SEMA4C/BRD2/SOX4/LRP2/IRX2/LMO4/GATA3 13 GO:0045785 positive regulation of cell adhesion 25/445 437/18722 5.15178016773021e-05 0.00518934210733213 TPM1/PLEKHA2/CD74/MYADM/HLA-DRA/SFRP1/HLA-DRB1/ANXA1/FERMT2/SLC7A1/SOX4/HLA-DPA1/LIMS1/HLA-A/HLA-DPB1/AIF1/PLPP3/CCDC80/TJP1/JAK1/PIK3CA/CALR/RHOA/GATA3/NFKBIZ 25 GO:1902895 positive regulation of pri-miRNA transcription by RNA polymerase II 7/445 42/18722 5.3711723130399e-05 0.00518934210733213 FOS/KLF4/GNL3/JUN/KLF5/PPARG/GATA3 7 GO:0002181 cytoplasmic translation 13/445 148/18722 5.40163908533724e-05 0.00518934210733213 RPL39/RPS15/RPL23/RPS12/EIF4H/RPS19/DENR/RPL28/RPS28/RPS11/RPLP1/TMA7/RPL29 13 GO:0002934 desmosome organization 4/445 10/18722 5.90243226813111e-05 0.00535080614292311 PKP3/GRHL1/PKP2/DSP 4 GO:0045936 negative regulation of phosphate metabolic process 25/445 441/18722 5.96656671617429e-05 0.00535080614292311 IGFBP3/APOE/APOC1/LPCAT1/ANKLE2/MYADM/SFRP1/PPP1R15A/TAF7/AIDA/INHA/SH3BP5/GSTP1/PMEPA1/PAK2/WNK1/PARP14/CBL/PLPP3/PPARG/WWTR1/DNAJC3/MLLT1/CDA/DNAJA1 25 GO:0010563 negative regulation of phosphorus metabolic process 25/445 442/18722 6.18754689359862e-05 0.00535080614292311 IGFBP3/APOE/APOC1/LPCAT1/ANKLE2/MYADM/SFRP1/PPP1R15A/TAF7/AIDA/INHA/SH3BP5/GSTP1/PMEPA1/PAK2/WNK1/PARP14/CBL/PLPP3/PPARG/WWTR1/DNAJC3/MLLT1/CDA/DNAJA1 25 GO:0051098 regulation of binding 22/445 363/18722 6.23982666583393e-05 0.00535080614292311 APOE/KLF4/TMSB4X/STK3/CTNNB1/SRI/PHLDA2/HMOX1/JUN/CPNE1/SP100/GOLGA2/CTBP2/EIF4A3/HSP90AB1/MBD2/PLK2/PLCL2/PPARG/RSF1/TCF7L2/GATA3 22 GO:1903311 regulation of mRNA metabolic process 19/445 288/18722 6.44191828575257e-05 0.00535080614292311 SFSWAP/VIM/IWS1/NCL/SRSF4/PKP3/MEX3D/SAFB/HNRNPM/RBM39/YBX1/YTHDC1/SRSF9/HNRNPA1/KHDRBS1/SERBP1/RBM3/HNRNPR/SRSF2 19 GO:0002396 MHC protein complex assembly 5/445 19/18722 6.54807836218146e-05 0.00535080614292311 HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1/CALR 5 GO:0002483 antigen processing and presentation of endogenous peptide antigen 5/445 19/18722 6.54807836218146e-05 0.00535080614292311 HLA-B/HLA-DRA/HLA-DRB1/HLA-C/HLA-A 5 GO:0008154 actin polymerization or depolymerization 16/445 217/18722 6.60729782124607e-05 0.00535080614292311 TMSB4X/MYADM/LIMA1/CDC42EP3/HAX1/DSTN/TMOD3/KANK4/GSN/MICAL3/AIF1/CAPZA2/GRB2/PIK3CA/RDX/RHOA 16 GO:0030522 intracellular receptor signaling pathway 18/445 265/18722 6.87904714631444e-05 0.00535080614292311 SFRP1/TAF7/PIM1/TRIM24/RIOK3/PMEPA1/SAFB/RXRA/TMF1/THRB/CTBP2/HSPA1B/LSM14A/CALR/PPARG/LBH/RHOA/DNAJA1 18 GO:0043627 response to estrogen 9/445 75/18722 6.99451783388642e-05 0.00535080614292311 KRT19/CA2/WNT7A/SFRP1/LDHA/HMOX1/TRIM24/CTNNA1/GATA3 9 GO:0048662 negative regulation of smooth muscle cell proliferation 9/445 75/18722 6.99451783388642e-05 0.00535080614292311 IGFBP3/TPM1/APOE/KLF4/HMOX1/GSTP1/AIF1/PPARG/RHOA 9 GO:0045185 maintenance of protein location 10/445 93/18722 7.22817908478276e-05 0.00540893158865795 TMSB4X/FBN2/SRI/MORC3/GOPC/TAF3/SP100/GSN/SRGN/GOLPH3 10 GO:0030042 actin filament depolymerization 8/445 59/18722 7.33236913495147e-05 0.00540893158865795 LIMA1/DSTN/TMOD3/GSN/MICAL3/CAPZA2/PIK3CA/RDX 8 GO:0010595 positive regulation of endothelial cell migration 12/445 133/18722 8.02509290301287e-05 0.00581608048813091 TMSB4X/WNT7A/ANXA1/HMOX1/RHOB/SASH1/PLK2/PLPP3/CALR/SPARC/GATA3/PDCD6 12 GO:0015669 gas transport 5/445 20/18722 8.56103077474974e-05 0.0059673245146688 CA2/HBA2/HBA1/HBG2/HBB 5 GO:0042773 ATP synthesis coupled electron transport 10/445 95/18722 8.66713800242382e-05 0.0059673245146688 UQCR10/UQCRQ/COX6C/COX7C/NDUFB2/NDUFA3/COX6A1/NDUFB1/NDUFA4/COX4I1 10 GO:0042775 mitochondrial ATP synthesis coupled electron transport 10/445 95/18722 8.66713800242382e-05 0.0059673245146688 UQCR10/UQCRQ/COX6C/COX7C/NDUFB2/NDUFA3/COX6A1/NDUFB1/NDUFA4/COX4I1 10 GO:0010038 response to metal ion 22/445 373/18722 9.2864367253191e-05 0.00628889673972019 FOS/JUND/CA2/SLC25A24/BNIP3/HMOX1/S100A8/HSD17B1/JUN/FOSB/CPNE1/NDRG1/MT2A/WNK1/TXNIP/C1QA/SERPINF1/PLSCR1/CALR/GGH/SPARC/PDCD6 22 GO:0051017 actin filament bundle assembly 13/445 157/18722 9.90905328303266e-05 0.00639598423628249 TPM1/LIMA1/ARHGEF5/SFRP1/PAWR/FERMT2/PAK2/AIF1/TJP1/CALD1/RDX/RGCC/RHOA 13 GO:1902107 positive regulation of leukocyte differentiation 13/445 157/18722 9.90905328303266e-05 0.00639598423628249 FOS/CA2/CD74/HLA-DRA/HLA-DRB1/TYROBP/ANXA1/HAX1/JUN/SOX4/RHOA/GATA3/NFKBIZ 13 GO:1903708 positive regulation of hemopoiesis 13/445 157/18722 9.90905328303266e-05 0.00639598423628249 FOS/CA2/CD74/HLA-DRA/HLA-DRB1/TYROBP/ANXA1/HAX1/JUN/SOX4/RHOA/GATA3/NFKBIZ 13 GO:0048660 regulation of smooth muscle cell proliferation 14/445 180/18722 0.000106162432674727 0.0066841647630008 IGFBP3/TPM1/APOE/KLF4/CTNNB1/HMOX1/GSTP1/JUN/ADAMTS1/AIF1/HPGD/PPARG/RHOA/TCF7L2 14 GO:0050684 regulation of mRNA processing 12/445 137/18722 0.000106791303403063 0.0066841647630008 SFSWAP/IWS1/NCL/SRSF4/SAFB/RBM39/YTHDC1/SRSF9/HNRNPA1/KHDRBS1/RBM3/SRSF2 12 GO:0051101 regulation of DNA binding 11/445 118/18722 0.000117993076597994 0.00716807940332816 KLF4/TMSB4X/CTNNB1/SRI/HMOX1/JUN/CPNE1/SP100/PPARG/RSF1/GATA3 11 GO:0071346 cellular response to interferon-gamma 11/445 118/18722 0.000117993076597994 0.00716807940332816 VIM/SP100/HLA-DPA1/IRF1/HSP90AB1/PARP14/CDC37/AIF1/JAK1/PPARG/GBP1 11 GO:0097305 response to alcohol 17/445 253/18722 0.000124058190957967 0.00742730995430956 FOS/KLF4/SFRP1/CTNNB1/S100A8/GSTP1/FOSB/FDX1/GNB1/CBL/HPGD/CTNNA1/GGH/RHOA/SPARC/GOLPH3/GATA3 17 GO:0048659 smooth muscle cell proliferation 14/445 184/18722 0.000134073096856107 0.00791222804446541 IGFBP3/TPM1/APOE/KLF4/CTNNB1/HMOX1/GSTP1/JUN/ADAMTS1/AIF1/HPGD/PPARG/RHOA/TCF7L2 14 GO:0002761 regulation of myeloid leukocyte differentiation 11/445 120/18722 0.000137193332915285 0.00794360507766654 FOS/CA2/CD74/CEBPB/SFRP1/CTNNB1/HLA-DRB1/TYROBP/HAX1/INHA/JUN 11 GO:0010631 epithelial cell migration 21/445 357/18722 0.000138450633161944 0.00794360507766654 APOE/KLF4/TMSB4X/WNT7A/ANXA1/HMOX1/RHOB/SP100/SASH1/PLK2/PLPP3/SERPINF1/MACF1/PIK3CA/CALR/PPARG/RGCC/RHOA/SPARC/GATA3/PDCD6 21 GO:0034341 response to interferon-gamma 12/445 141/18722 0.000140542765179118 0.00795318031445119 CD74/VIM/SP100/HLA-DPA1/IRF1/HSP90AB1/PARP14/CDC37/AIF1/JAK1/PPARG/GBP1 12 GO:0048024 regulation of mRNA splicing, via spliceosome 10/445 101/18722 0.00014522799009839 0.0081072544202223 SFSWAP/NCL/SRSF4/RBM39/YTHDC1/SRSF9/HNRNPA1/KHDRBS1/RBM3/SRSF2 10 GO:2000146 negative regulation of cell motility 21/445 359/18722 0.000149562242787238 0.00817499735191189 IGFBP3/TPM1/APOE/KLF4/CD74/SFRP1/SRGAP2B/HMOX1/GSTP1/RHOB/ZMYND8/SP100/AIF1/SERPINF1/CALR/PPARG/CLDN19/CTNNA1/RGCC/RHOA/GATA3 21 GO:0051090 regulation of DNA-binding transcription factor activity 24/445 440/18722 0.000150399370308715 0.00817499735191189 KLF4/TMSB4X/STK3/ARHGEF5/CTNNB1/NLRP2/S100A9/UBE2V1/SRI/PIM1/HMOX1/S100A8/SMARCB1/ANXA4/EIF2AK2/TAF3/SP100/EIF2AK4/ZNF431/HSPA1B/PLPP3/PPARG/RGCC/TCF7L2 24 GO:0090132 epithelium migration 21/445 360/18722 0.00015540804128457 0.00831325310644223 APOE/KLF4/TMSB4X/WNT7A/ANXA1/HMOX1/RHOB/SP100/SASH1/PLK2/PLPP3/SERPINF1/MACF1/PIK3CA/CALR/PPARG/RGCC/RHOA/SPARC/GATA3/PDCD6 21 GO:0001841 neural tube formation 10/445 102/18722 0.000157660480232513 0.00831325310644223 MTHFD1L/STK3/LUZP1/SFRP1/SPINT1/SEMA4C/BRD2/SOX4/LRP2/LMO4 10 GO:0008064 regulation of actin polymerization or depolymerization 14/445 187/18722 0.000158980148973357 0.00831325310644223 TMSB4X/MYADM/LIMA1/CDC42EP3/HAX1/DSTN/TMOD3/KANK4/GSN/CAPZA2/GRB2/PIK3CA/RDX/RHOA 14 GO:0030832 regulation of actin filament length 14/445 188/18722 0.000168126215707664 0.00861192810599591 TMSB4X/MYADM/LIMA1/CDC42EP3/HAX1/DSTN/TMOD3/KANK4/GSN/CAPZA2/GRB2/PIK3CA/RDX/RHOA 14 GO:1903037 regulation of leukocyte cell-cell adhesion 20/445 336/18722 0.000169770903459131 0.00861192810599591 KLF4/CD74/HLA-DRA/CEBPB/HLA-DRB1/ANXA1/PAWR/SLC7A1/SOX4/HLA-DPA1/WNK1/IRF1/HLA-A/HLA-DPB1/AIF1/PIK3CA/RHOA/LAPTM5/GATA3/NFKBIZ 20 GO:0050852 T cell receptor signaling pathway 11/445 123/18722 0.000170946043256273 0.00861192810599591 HLA-DRB1/PAWR/WNK1/HLA-A/HLA-DPB1/KHDRBS1/PIK3CA/GBP1/LAPTM5/GATA3/NFKBIZ 11 GO:0062197 cellular response to chemical stress 20/445 337/18722 0.000176602256780968 0.00878968581641182 FOS/TPM1/KLF4/PAGE4/CTNNB1/SLC25A24/ANXA1/PAWR/MAPKAP1/BNIP3/HMOX1/RHOB/JUN/NET1/HSPA1B/AIF1/MCL1/PIK3CA/ATF4/DNAJA1 20 GO:0040013 negative regulation of locomotion 22/445 391/18722 0.000182251294589455 0.00895820994612962 IGFBP3/TPM1/APOE/KLF4/CD74/SFRP1/SRGAP2B/SEMA4C/HMOX1/GSTP1/RHOB/ZMYND8/SP100/AIF1/SERPINF1/CALR/PPARG/CLDN19/CTNNA1/RGCC/RHOA/GATA3 22 GO:0051651 maintenance of location in cell 15/445 213/18722 0.000184325307533531 0.00895820994612962 FTL/APOE/TMSB4X/S100A9/SRI/MORC3/ERO1A/S100A8/ARHGAP21/TAF3/SP100/GSN/SRGN/CALR/GOLPH3 15 GO:0090130 tissue migration 21/445 365/18722 0.000187770879296307 0.00901955235317494 APOE/KLF4/TMSB4X/WNT7A/ANXA1/HMOX1/RHOB/SP100/SASH1/PLK2/PLPP3/SERPINF1/MACF1/PIK3CA/CALR/PPARG/RGCC/RHOA/SPARC/GATA3/PDCD6 21 GO:0048545 response to steroid hormone 20/445 339/18722 0.000190994576002176 0.00906894935017229 FOS/CA2/SFRP1/TAF7/SPP1/ANXA1/GSTP1/FOSB/PMEPA1/SAFB/RXRA/TMF1/TXNIP/AIF1/SERPINF1/CALR/LBH/RHOA/SPARC/DNAJA1 20 GO:0034599 cellular response to oxidative stress 18/445 288/18722 0.000196147217531226 0.00920777449569882 FOS/TPM1/KLF4/PAGE4/CTNNB1/SLC25A24/ANXA1/PAWR/MAPKAP1/BNIP3/HMOX1/RHOB/JUN/NET1/HSPA1B/AIF1/MCL1/ATF4 18 GO:0051271 negative regulation of cellular component movement 21/445 367/18722 0.000202294138201407 0.00938963016752824 IGFBP3/TPM1/APOE/KLF4/CD74/SFRP1/SRGAP2B/HMOX1/GSTP1/RHOB/ZMYND8/SP100/AIF1/SERPINF1/CALR/PPARG/CLDN19/CTNNA1/RGCC/RHOA/GATA3 21 GO:0045765 regulation of angiogenesis 20/445 342/18722 0.000214517435058281 0.00984635026917511 KLF4/SFRP1/CTNNB1/EPN2/HMOX1/RHOB/HTATIP2/ADAMTS1/SP100/HSPG2/SASH1/ANGPTL4/PLK2/SERPINF1/TJP1/JAK1/PPARG/RGCC/SPARC/PDCD6 20 GO:0043392 negative regulation of DNA binding 7/445 52/18722 0.000217126874888326 0.00985660571608434 TMSB4X/SRI/HMOX1/JUN/CPNE1/SP100/RSF1 7 GO:0043558 regulation of translational initiation in response to stress 4/445 14/18722 0.000260845171777438 0.0117125152675282 PPP1R15A/EIF2AK2/EIF2AK4/DNAJC3 4 GO:2001236 regulation of extrinsic apoptotic signaling pathway 12/445 151/18722 0.00026713209769061 0.0118352157354045 SKIL/STK3/SFRP1/HMOX1/GSTP1/SP100/PAK2/RB1CC1/HSPA1B/MCL1/CTNNA1/TCF7L2 12 GO:1901342 regulation of vasculature development 20/445 348/18722 0.000269307741255875 0.0118352157354045 KLF4/SFRP1/CTNNB1/EPN2/HMOX1/RHOB/HTATIP2/ADAMTS1/SP100/HSPG2/SASH1/ANGPTL4/PLK2/SERPINF1/TJP1/JAK1/PPARG/RGCC/SPARC/PDCD6 20 GO:0030834 regulation of actin filament depolymerization 7/445 54/18722 0.000275940465145849 0.0118740631408073 LIMA1/DSTN/TMOD3/GSN/CAPZA2/PIK3CA/RDX 7 GO:1902893 regulation of pri-miRNA transcription by RNA polymerase II 7/445 54/18722 0.000275940465145849 0.0118740631408073 FOS/KLF4/GNL3/JUN/KLF5/PPARG/GATA3 7 GO:0061614 pri-miRNA transcription by RNA polymerase II 7/445 55/18722 0.000309802924227371 0.0131937719585904 FOS/KLF4/GNL3/JUN/KLF5/PPARG/GATA3 7 GO:0032984 protein-containing complex disassembly 15/445 224/18722 0.00031761667748195 0.0132979867776772 LIMA1/CCSAP/DSTN/BNIP3/SMARCB1/TMOD3/RPL23/KIF2A/GSN/MICAL3/CHMP5/CAPZA2/PIK3CA/RDX/VAMP8 15 GO:0045216 cell-cell junction organization 14/445 200/18722 0.000318688136284203 0.0132979867776772 CTNNB1/PKP3/FERMT2/GRHL1/PKP2/CLDN7/PAK2/LIMS1/TJP1/CLDN19/RDX/DSP/CTNNA1/RHOA 14 GO:0015671 oxygen transport 4/445 15/18722 0.000349045447510569 0.0139990945987006 HBA2/HBA1/HBG2/HBB 4 GO:0032486 Rap protein signal transduction 4/445 15/18722 0.000349045447510569 0.0139990945987006 RAP1B/CBL/PLK2/RDX 4 GO:0043508 negative regulation of JUN kinase activity 4/445 15/18722 0.000349045447510569 0.0139990945987006 SFRP1/AIDA/GSTP1/DNAJA1 4 GO:0048569 post-embryonic animal organ development 4/445 15/18722 0.000349045447510569 0.0139990945987006 KLF4/LDHA/HMGN1/EFEMP1 4 GO:0050863 regulation of T cell activation 19/445 329/18722 0.000358389134987233 0.0142356299676179 CD74/HLA-DRA/CEBPB/CTNNB1/HLA-DRB1/ANXA1/PAWR/SLC7A1/SOX4/HLA-DPA1/IRF1/HLA-A/HLA-DPB1/AIF1/PIK3CA/RHOA/LAPTM5/GATA3/NFKBIZ 19 GO:0042326 negative regulation of phosphorylation 21/445 385/18722 0.000384362293660789 0.0149729152827859 IGFBP3/APOE/ANKLE2/MYADM/SFRP1/TAF7/AIDA/INHA/SH3BP5/GSTP1/PMEPA1/PAK2/WNK1/PARP14/CBL/PLPP3/PPARG/WWTR1/DNAJC3/MLLT1/DNAJA1 21 GO:0022904 respiratory electron transport chain 10/445 114/18722 0.000391448765563029 0.0149729152827859 UQCR10/UQCRQ/COX6C/COX7C/NDUFB2/NDUFA3/COX6A1/NDUFB1/NDUFA4/COX4I1 10 GO:0051261 protein depolymerization 10/445 114/18722 0.000391448765563029 0.0149729152827859 LIMA1/CCSAP/DSTN/TMOD3/KIF2A/GSN/MICAL3/CAPZA2/PIK3CA/RDX 10 GO:1903008 organelle disassembly 10/445 114/18722 0.000391448765563029 0.0149729152827859 ATG12/HAX1/GABARAP/BNIP3/GOLGA2/BNIP3L/RB1CC1/DENR/CDC37/UFC1 10 GO:0045444 fat cell differentiation 15/445 229/18722 0.000401523332421045 0.0152173659287279 KLF4/STK3/CEBPB/SFRP1/ERO1A/PIM1/BNIP3/FERMT2/CTBP2/ADIRF/KLF5/PPARG/WWTR1/TCF7L2/GATA3 15 GO:0070997 neuron death 20/445 361/18722 0.000431623564226956 0.0159273089387913 FOS/APOE/CEBPB/CTNNB1/TYROBP/BNIP3/HMOX1/JUN/RRAS2/THRB/UBE2V2/HSP90AB1/CBL/C1QA/SERPINF1/MCL1/PIK3CA/ATF4/RHOA/GATA3 20 GO:0002763 positive regulation of myeloid leukocyte differentiation 7/445 58/18722 0.000431822464571443 0.0159273089387913 FOS/CA2/CD74/HLA-DRB1/TYROBP/HAX1/JUN 7 GO:0034340 response to type I interferon 7/445 58/18722 0.000431822464571443 0.0159273089387913 IFNAR1/SP100/MX1/HSP90AB1/CDC37/LSM14A/JAK1 7 GO:0002399 MHC class II protein complex assembly 4/445 16/18722 0.000456696743585658 0.0161249081004475 HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1 4 GO:0002503 peptide antigen assembly with MHC class II protein complex 4/445 16/18722 0.000456696743585658 0.0161249081004475 HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1 4 GO:0051238 sequestering of metal ion 4/445 16/18722 0.000456696743585658 0.0161249081004475 FTL/S100A9/SRI/S100A8 4 GO:0060330 regulation of response to interferon-gamma 4/445 16/18722 0.000456696743585658 0.0161249081004475 HSP90AB1/PARP14/CDC37/PPARG 4 GO:0060334 regulation of interferon-gamma-mediated signaling pathway 4/445 16/18722 0.000456696743585658 0.0161249081004475 HSP90AB1/PARP14/CDC37/PPARG 4 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 5/445 28/18722 0.000463993334020311 0.0162436988376094 HLA-B/FCER1G/HLA-C/HLA-A/CALR 5 GO:0000380 alternative mRNA splicing, via spliceosome 8/445 77/18722 0.000479671196765605 0.0165792963748699 SFSWAP/RBM17/HNRNPM/YTHDC1/SRSF9/HNRNPA1/KHDRBS1/SRSF2 8 GO:0022409 positive regulation of cell-cell adhesion 17/445 284/18722 0.000481606285399271 0.0165792963748699 CD74/HLA-DRA/HLA-DRB1/ANXA1/SLC7A1/SOX4/HLA-DPA1/HLA-A/HLA-DPB1/AIF1/PLPP3/TJP1/JAK1/PIK3CA/RHOA/GATA3/NFKBIZ 17 GO:0001709 cell fate determination 6/445 43/18722 0.000504426222398881 0.0172213613614031 KLF4/IFRD1/WNT7A/CTNNB1/MCL1/GATA3 6 GO:0031333 negative regulation of protein-containing complex assembly 11/445 140/18722 0.000524999557717572 0.0177768292863221 TMSB4X/MYADM/AIDA/TMOD3/RIOK3/PMEPA1/KANK4/GSN/CAPZA2/LMO4/RDX 11 GO:1903706 regulation of hemopoiesis 20/445 367/18722 0.000531642568417884 0.0178554101636933 FOS/CA2/CD74/HLA-B/HLA-DRA/CEBPB/SFRP1/CTNNB1/HLA-DRB1/TYROBP/ANXA1/HAX1/INHA/JUN/SOX4/IRF1/HSPA1B/RHOA/GATA3/NFKBIZ 20 GO:0006119 oxidative phosphorylation 11/445 141/18722 0.00055753051708621 0.0185738594038962 UQCR10/UQCRQ/COX6C/COX7C/NDUFB2/RHOA/NDUFA3/COX6A1/NDUFB1/NDUFA4/COX4I1 11 GO:0006446 regulation of translational initiation 8/445 79/18722 0.000570707327055137 0.0188607357445182 PPP1R15A/EIF2AK2/EIF1B/EIF4H/EIF2AK4/KHDRBS1/DNAJC3/ATF4 8 GO:0007052 mitotic spindle organization 10/445 120/18722 0.000588627272092524 0.0192985655636049 CCSAP/KIF2A/GOLGA2/SBDS/CHMP5/HSPA1B/PLK2/MAP4/LSM14A/RHOA 10 GO:0030336 negative regulation of cell migration 19/445 344/18722 0.000618497787793089 0.0201182233178996 IGFBP3/TPM1/APOE/KLF4/CD74/SFRP1/SRGAP2B/HMOX1/GSTP1/RHOB/ZMYND8/SP100/AIF1/SERPINF1/CALR/PPARG/CLDN19/RGCC/RHOA 19 GO:1902904 negative regulation of supramolecular fiber organization 12/445 166/18722 0.000630970384904619 0.0201463143962488 APOE/TMSB4X/MYADM/LIMA1/TMOD3/KANK4/GSN/PAK2/CAPZA2/TJP1/PIK3CA/RDX 12 GO:0002429 immune response-activating cell surface receptor signaling pathway 17/445 291/18722 0.00063399198051618 0.0201463143962488 HLA-DRB1/TYROBP/PAWR/VAV2/FCER1G/PAK2/WNK1/HLA-A/HLA-DPB1/KHDRBS1/PLSCR1/PIK3CA/PLCL2/GBP1/LAPTM5/GATA3/NFKBIZ 17 GO:0002757 immune response-activating signal transduction 17/445 291/18722 0.00063399198051618 0.0201463143962488 HLA-DRB1/TYROBP/PAWR/VAV2/FCER1G/PAK2/WNK1/HLA-A/HLA-DPB1/KHDRBS1/PLSCR1/PIK3CA/PLCL2/GBP1/LAPTM5/GATA3/NFKBIZ 17 GO:0017145 stem cell division 5/445 30/18722 0.000647024463356741 0.0202642904614538 GNL3/WNT7A/ING2/WWTR1/LBH 5 GO:0030835 negative regulation of actin filament depolymerization 6/445 45/18722 0.000647515454106003 0.0202642904614538 LIMA1/TMOD3/GSN/CAPZA2/PIK3CA/RDX 6 GO:1901214 regulation of neuron death 18/445 319/18722 0.000666520602408372 0.0207022301394661 FOS/APOE/CEBPB/CTNNB1/TYROBP/HMOX1/JUN/RRAS2/UBE2V2/HSP90AB1/CBL/C1QA/SERPINF1/MCL1/PIK3CA/ATF4/RHOA/GATA3 18 GO:0050870 positive regulation of T cell activation 14/445 216/18722 0.0006884947783199 0.0212251636510411 CD74/HLA-DRA/HLA-DRB1/ANXA1/SLC7A1/SOX4/HLA-DPA1/HLA-A/HLA-DPB1/AIF1/PIK3CA/RHOA/GATA3/NFKBIZ 14 GO:0002253 activation of immune response 20/445 375/18722 0.000695893303133683 0.0212943350758907 HLA-DRB1/TYROBP/PAWR/VAV2/FCER1G/PAK2/WNK1/HLA-A/C1QB/HLA-DPB1/C1QA/KHDRBS1/PLSCR1/PIK3CA/PLCL2/GBP1/RGCC/LAPTM5/GATA3/NFKBIZ 20 GO:1903320 regulation of protein modification by small protein conjugation or removal 15/445 242/18722 0.000713504498216586 0.0216726991333288 GNL3/CTNNB1/UBXN2A/GABARAP/RPS15/UBE2D1/RPL23/SOX4/SASH1/HSP90AB1/HSPA1B/BIRC7/LAPTM5/PDCD6/DNAJA1 15 GO:0045088 regulation of innate immune response 14/445 218/18722 0.000753569810106619 0.0227226050040178 APOE/HLA-B/TYROBP/RIOK3/PAK2/IRF1/HLA-A/HSP90AB1/PARP14/RPS19/CDC37/PLSCR1/LSM14A/PPARG 14 GO:0097191 extrinsic apoptotic signaling pathway 14/445 219/18722 0.000788010336012107 0.0233021797028339 SKIL/STK3/KRT8/SFRP1/GABARAP/HMOX1/GSTP1/SP100/PAK2/RB1CC1/HSPA1B/MCL1/CTNNA1/TCF7L2 14 GO:0030837 negative regulation of actin filament polymerization 7/445 64/18722 0.000789713182860505 0.0233021797028339 TMSB4X/MYADM/TMOD3/KANK4/GSN/CAPZA2/RDX 7 GO:0032507 maintenance of protein location in cell 7/445 64/18722 0.000789713182860505 0.0233021797028339 TMSB4X/MORC3/TAF3/SP100/GSN/SRGN/GOLPH3 7 GO:0051402 neuron apoptotic process 15/445 246/18722 0.00084359810307613 0.0247156295305496 APOE/CEBPB/CTNNB1/TYROBP/BNIP3/HMOX1/JUN/THRB/UBE2V2/HSP90AB1/MCL1/PIK3CA/ATF4/RHOA/GATA3 15 GO:0001819 positive regulation of cytokine production 23/445 467/18722 0.000851954788392005 0.0247846847242773 CD74/CEBPB/NLRP2/TYROBP/ANXA1/HMOX1/EIF2AK2/RIOK3/FCER1G/TMF1/HLA-DPA1/IRF1/HLA-A/HSPA1B/HLA-DPB1/AIF1/AKAP12/HILPDA/SLC7A5/ATF4/RGCC/LAPTM5/GATA3 23 GO:0008406 gonad development 14/445 221/18722 0.000860893016329377 0.0248695737794172 CGA/CEBPB/SFRP1/ING2/INHA/ADAMTS1/FNDC3A/TMF1/BASP1/LRP2/CBL/CTNNA1/NRIP1/GATA3 14 GO:0090307 mitotic spindle assembly 7/445 65/18722 0.000867232971536618 0.0248787458709567 CCSAP/KIF2A/GOLGA2/CHMP5/HSPA1B/LSM14A/RHOA 7 GO:0032231 regulation of actin filament bundle assembly 9/445 105/18722 0.000895436893452581 0.0253752837809456 TPM1/ARHGEF5/SFRP1/FERMT2/PAK2/TJP1/RDX/RGCC/RHOA 9 GO:0071248 cellular response to metal ion 13/445 197/18722 0.000896826780929086 0.0253752837809456 FOS/JUND/SLC25A24/BNIP3/HMOX1/HSD17B1/JUN/FOSB/CPNE1/MT2A/WNK1/SERPINF1/CALR 13 GO:0051099 positive regulation of binding 12/445 173/18722 0.000908128930129055 0.0254841826493136 APOE/KLF4/STK3/CTNNB1/CTBP2/HSP90AB1/MBD2/PLK2/PLCL2/PPARG/TCF7L2/GATA3 12 GO:0033002 muscle cell proliferation 15/445 248/18722 0.000915846114481571 0.0254841826493136 IGFBP3/TPM1/APOE/KLF4/CTNNB1/PIM1/HMOX1/GSTP1/JUN/ADAMTS1/AIF1/HPGD/PPARG/RHOA/TCF7L2 15 GO:2000269 regulation of fibroblast apoptotic process 4/445 19/18722 0.000919182574376113 0.0254841826493136 SFRP1/CFDP1/IER3IP1/PIK3CA 4 GO:0045600 positive regulation of fat cell differentiation 7/445 66/18722 0.000950631166191473 0.0261803823169132 STK3/CEBPB/SFRP1/PIM1/ADIRF/KLF5/PPARG 7 GO:0007548 sex differentiation 16/445 276/18722 0.000983294554363969 0.0269005947289904 WNT7A/CGA/CEBPB/SFRP1/CTNNB1/ING2/INHA/ADAMTS1/FNDC3A/TMF1/BASP1/LRP2/CBL/CTNNA1/NRIP1/GATA3 16 GO:0032633 interleukin-4 production 5/445 33/18722 0.00101636744358128 0.0273542232844231 CEBPB/HLA-DRB1/FCER1G/SLC7A5/GATA3 5 GO:0032673 regulation of interleukin-4 production 5/445 33/18722 0.00101636744358128 0.0273542232844231 CEBPB/HLA-DRB1/FCER1G/SLC7A5/GATA3 5 GO:0034332 adherens junction organization 6/445 49/18722 0.00102636277150462 0.0273542232844231 CTNNB1/FERMT2/PAK2/TJP1/RDX/DSP 6 GO:0060986 endocrine hormone secretion 6/445 49/18722 0.00102636277150462 0.0273542232844231 CGA/INHA/TMF1/RAB8B/GATA3/RAB11FIP1 6 GO:0031667 response to nutrient levels 23/445 474/18722 0.00103867281417575 0.0273816471317299 APOE/PAGE4/SFRP1/SPP1/LDHA/GABARAP/PIM1/BNIP3/HMOX1/GSTP1/EIF2AK2/JUN/TRIM24/EIF2AK4/MBD2/CBL/HNRNPA1/PPARG/ATF4/CSH1/SRSF2/SPARC/COX4I1 23 GO:0021915 neural tube development 11/445 152/18722 0.00104064841435042 0.0273816471317299 MTHFD1L/STK3/LUZP1/SFRP1/SPINT1/SEMA4C/BRD2/SOX4/LRP2/TMEM107/LMO4 11 GO:0010634 positive regulation of epithelial cell migration 12/445 176/18722 0.00105464863014358 0.0274125030806002 TMSB4X/WNT7A/ANXA1/HMOX1/RHOB/SASH1/PLK2/PLPP3/CALR/SPARC/GATA3/PDCD6 12 GO:0001667 ameboidal-type cell migration 23/445 475/18722 0.0010680388549933 0.0274125030806002 APOE/KLF4/TMSB4X/WNT7A/ANXA1/SEMA4C/HMOX1/RHOB/SP100/SASH1/PLK2/PLPP3/SERPINF1/AKAP12/MACF1/PIK3CA/CALR/PPARG/RGCC/RHOA/SPARC/GATA3/PDCD6 23 GO:0051495 positive regulation of cytoskeleton organization 14/445 226/18722 0.00106836431759299 0.0274125030806002 TPM1/ARHGEF5/SFRP1/CDC42EP3/HAX1/DSTN/CENPJ/GSN/FERMT2/KATNBL1/HSPA1B/GRB2/RGCC/RHOA 14 GO:0071241 cellular response to inorganic substance 14/445 226/18722 0.00106836431759299 0.0274125030806002 FOS/JUND/SLC25A24/BNIP3/HMOX1/HSD17B1/JUN/FOSB/CPNE1/MT2A/WNK1/EIF4A3/SERPINF1/CALR 14 GO:0045137 development of primary sexual characteristics 14/445 227/18722 0.0011145341321666 0.0284206203702484 CGA/CEBPB/SFRP1/ING2/INHA/ADAMTS1/FNDC3A/TMF1/BASP1/LRP2/CBL/CTNNA1/NRIP1/GATA3 14 GO:0043555 regulation of translation in response to stress 4/445 20/18722 0.00112757564103327 0.0285767789761253 PPP1R15A/EIF2AK2/EIF2AK4/DNAJC3 4 GO:0001961 positive regulation of cytokine-mediated signaling pathway 6/445 50/18722 0.00114329480177321 0.0286239444007582 CD74/CPNE1/PARP14/HSPA1B/LSM14A/LAPTM5 6 GO:0060337 type I interferon signaling pathway 6/445 50/18722 0.00114329480177321 0.0286239444007582 IFNAR1/SP100/HSP90AB1/CDC37/LSM14A/JAK1 6 GO:0050869 negative regulation of B cell activation 5/445 34/18722 0.00116862484951819 0.029081862972046 SFRP1/TYROBP/PAWR/INHA/LAPTM5 5 GO:0001649 osteoblast differentiation 14/445 229/18722 0.00121191070547721 0.0299784618223136 JUND/CEBPB/SFRP1/FBN2/CTNNB1/SPP1/MRC2/RPS15/RRAS2/FERMT2/PPARG/FHL2/WWTR1/ATF4 14 GO:0071383 cellular response to steroid hormone stimulus 13/445 204/18722 0.00123405863526393 0.0302874822991817 SFRP1/TAF7/ANXA1/GSTP1/PMEPA1/SAFB/RXRA/TMF1/SERPINF1/CALR/LBH/RHOA/DNAJA1 13 GO:0042060 wound healing 21/445 422/18722 0.00124227993727133 0.0302874822991817 TPM1/APOE/WNT7A/ANXA1/VAV2/CSRP1/HMOX1/S100A8/FERMT2/FCER1G/PLPP3/PLSCR1/MACF1/MYOF/PIK3CA/CLDN19/DSP/HBB/RHOA/SPARC/F5 21 GO:0007265 Ras protein signal transduction 18/445 337/18722 0.001246398448526 0.0302874822991817 APOE/CDC42EP3/RAP1B/GABARAP/MAPKAP1/ARHGAP29/RHOB/JUN/RRAS2/SHTN1/NET1/GNB1/CBL/PLK2/AIF1/GRB2/RDX/RHOA 18 GO:0045333 cellular respiration 14/445 230/18722 0.00126321165675056 0.0305165342341319 BNIP3/IFNAR1/UQCR10/UQCRQ/COX6C/PIK3CA/COX7C/NDUFB2/RHOA/NDUFA3/COX6A1/NDUFB1/NDUFA4/COX4I1 14 GO:0001701 in utero embryonic development 19/445 367/18722 0.00132830995735824 0.0317181990395773 KRT19/KLF4/SKIL/STK3/CEBPB/KRT8/CTNNB1/SPINT1/TANC2/PHLDA2/SMARCB1/SBDS/YBX1/YTHDC1/GRB2/RTF1/GATA3/CMIP/CIR1 19 GO:0140694 non-membrane-bounded organelle assembly 19/445 367/18722 0.00132830995735824 0.0317181990395773 KRT19/TPM1/KRT8/CCSAP/CSRP1/TMOD3/RPS15/KIF2A/CENPJ/GOLGA2/GSN/SBDS/CHMP5/RPS19/HSPA1B/PLK2/RPS28/LSM14A/RHOA 19 GO:1904705 regulation of vascular associated smooth muscle cell proliferation 8/445 90/18722 0.00135244248795024 0.0320847915413682 TPM1/HMOX1/GSTP1/JUN/ADAMTS1/HPGD/PPARG/RHOA 8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen 4/445 21/18722 0.00136696279624323 0.0320847915413682 COX6C/COX7C/COX6A1/COX4I1 4 GO:0150105 protein localization to cell-cell junction 4/445 21/18722 0.00136696279624323 0.0320847915413682 PAK2/TJP1/JAK1/DSP 4 GO:1903131 mononuclear cell differentiation 21/445 426/18722 0.00139534656719695 0.0323157659978873 CD74/HLA-B/HLA-DRA/CEBPB/SFRP1/CTNNB1/HLA-DRB1/ANXA1/INHA/JUN/FCER1G/SOX4/KLF6/TPD52/NFIL3/IRF1/PLCL2/PPARG/RHOA/GATA3/NFKBIZ 21 GO:0051496 positive regulation of stress fiber assembly 6/445 52/18722 0.00140751735500388 0.0323157659978873 TPM1/ARHGEF5/SFRP1/FERMT2/RGCC/RHOA 6 GO:0071357 cellular response to type I interferon 6/445 52/18722 0.00140751735500388 0.0323157659978873 IFNAR1/SP100/HSP90AB1/CDC37/LSM14A/JAK1 6 GO:0010998 regulation of translational initiation by eIF2 alpha phosphorylation 3/445 10/18722 0.00141323087975697 0.0323157659978873 EIF2AK2/EIF2AK4/DNAJC3 3 GO:1901222 regulation of NIK/NF-kappaB signaling 9/445 112/18722 0.00141591712554287 0.0323157659978873 TMSB4X/LITAF/EIF2AK2/CPNE1/LIMS1/SASH1/CALR/RHOA/LAPTM5 9 GO:0045582 positive regulation of T cell differentiation 8/445 91/18722 0.00145267648341423 0.032614166048827 CD74/HLA-DRA/HLA-DRB1/ANXA1/SOX4/RHOA/GATA3/NFKBIZ 8 GO:0051492 regulation of stress fiber assembly 8/445 91/18722 0.00145267648341423 0.032614166048827 TPM1/ARHGEF5/SFRP1/FERMT2/PAK2/TJP1/RGCC/RHOA 8 GO:1990874 vascular associated smooth muscle cell proliferation 8/445 91/18722 0.00145267648341423 0.032614166048827 TPM1/HMOX1/GSTP1/JUN/ADAMTS1/HPGD/PPARG/RHOA 8 GO:0001933 negative regulation of protein phosphorylation 18/445 342/18722 0.00146868951543863 0.0326526733415675 IGFBP3/APOE/MYADM/SFRP1/TAF7/AIDA/SH3BP5/GSTP1/PMEPA1/PAK2/PARP14/CBL/PLPP3/PPARG/WWTR1/DNAJC3/MLLT1/DNAJA1 18 GO:0002573 myeloid leukocyte differentiation 13/445 208/18722 0.00147020025212577 0.0326526733415675 FOS/CA2/CD74/CEBPB/SFRP1/CTNNB1/HLA-DRB1/TYROBP/HAX1/INHA/JUN/PPARG/GATA3 13 GO:0002768 immune response-regulating cell surface receptor signaling pathway 17/445 315/18722 0.00150902951883006 0.0333358339159731 HLA-DRB1/TYROBP/PAWR/VAV2/FCER1G/PAK2/WNK1/HLA-A/HLA-DPB1/KHDRBS1/PLSCR1/PIK3CA/PLCL2/GBP1/LAPTM5/GATA3/NFKBIZ 17 GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 13/445 209/18722 0.00153475982487319 0.0334763399290035 KLF4/NLRP2/S100A9/S100A8/TNFAIP8/GSN/PAK2/BIRC7/CTSD/PPARG/RHOA/LAPTM5/PDCD6 13 GO:0043401 steroid hormone mediated signaling pathway 10/445 136/18722 0.00154227874171492 0.0334763399290035 SFRP1/TAF7/PMEPA1/SAFB/RXRA/TMF1/CALR/LBH/RHOA/DNAJA1 10 GO:0043624 cellular protein complex disassembly 10/445 136/18722 0.00154227874171492 0.0334763399290035 LIMA1/CCSAP/DSTN/TMOD3/KIF2A/GSN/MICAL3/CAPZA2/PIK3CA/RDX 10 GO:0002699 positive regulation of immune effector process 14/445 235/18722 0.00154780462997813 0.0334763399290035 CD74/HLA-B/HLA-DRA/HLA-DRB1/TYROBP/ANXA1/HMOX1/HLA-A/RPS19/SLC7A5/LAPTM5/GATA3/VAMP8/NFKBIZ 14 GO:0031396 regulation of protein ubiquitination 13/445 210/18722 0.00160165369960761 0.034382959191482 UBXN2A/GABARAP/RPS15/UBE2D1/RPL23/SOX4/SASH1/HSP90AB1/HSPA1B/BIRC7/LAPTM5/PDCD6/DNAJA1 13 GO:0043433 negative regulation of DNA-binding transcription factor activity 12/445 185/18722 0.0016165826097691 0.034382959191482 KLF4/TMSB4X/NLRP2/SRI/PIM1/HMOX1/ANXA4/TAF3/SP100/EIF2AK4/ZNF431/TCF7L2 12 GO:0006986 response to unfolded protein 10/445 137/18722 0.00162932700308161 0.034382959191482 PPP1R15A/ERO1A/HSPA2/EIF2AK2/HSP90AB1/HSPA1B/ERP44/DNAJC3/ATF4/DNAJA1 10 GO:0044346 fibroblast apoptotic process 4/445 22/18722 0.0016396618157158 0.034382959191482 SFRP1/CFDP1/IER3IP1/PIK3CA 4 GO:0060343 trabecula formation 4/445 22/18722 0.0016396618157158 0.034382959191482 SFRP1/FBN2/ADAMTS1/FHL2 4 GO:2000114 regulation of establishment of cell polarity 4/445 22/18722 0.0016396618157158 0.034382959191482 RAP1B/GSN/SHTN1/GATA3 4 GO:0051494 negative regulation of cytoskeleton organization 11/445 162/18722 0.00173969707509481 0.0359732552504473 TMSB4X/MYADM/LIMA1/TMOD3/KANK4/GSN/PAK2/CAPZA2/TJP1/PIK3CA/RDX 11 GO:0060759 regulation of response to cytokine stimulus 11/445 162/18722 0.00173969707509481 0.0359732552504473 KLF4/CD74/GSTP1/CPNE1/HSP90AB1/PARP14/HSPA1B/CDC37/LSM14A/PPARG/LAPTM5 11 GO:0043523 regulation of neuron apoptotic process 13/445 212/18722 0.00174270229179754 0.0359732552504473 APOE/CEBPB/CTNNB1/TYROBP/HMOX1/JUN/UBE2V2/HSP90AB1/MCL1/PIK3CA/ATF4/RHOA/GATA3 13 GO:0002683 negative regulation of immune system process 21/445 434/18722 0.0017503326810312 0.0359732552504473 CD74/HLA-B/CEBPB/SFRP1/CTNNB1/HLA-DRB1/TYROBP/ANXA1/PAWR/INHA/HMOX1/RIOK3/IRF1/HLA-A/PARP14/RPS19/PLK2/PLCL2/PPARG/GBP1/LAPTM5 21 GO:0014020 primary neural tube formation 8/445 94/18722 0.00178915671165718 0.0365819780570068 MTHFD1L/LUZP1/SFRP1/SPINT1/SEMA4C/BRD2/LRP2/LMO4 8 GO:0030518 intracellular steroid hormone receptor signaling pathway 9/445 116/18722 0.0018083082665063 0.0365819780570068 SFRP1/TAF7/PMEPA1/SAFB/TMF1/CALR/LBH/RHOA/DNAJA1 9 GO:1903039 positive regulation of leukocyte cell-cell adhesion 14/445 239/18722 0.00181228372543332 0.0365819780570068 CD74/HLA-DRA/HLA-DRB1/ANXA1/SLC7A1/SOX4/HLA-DPA1/HLA-A/HLA-DPB1/AIF1/PIK3CA/RHOA/GATA3/NFKBIZ 14 GO:0045598 regulation of fat cell differentiation 10/445 139/18722 0.00181537291253604 0.0365819780570068 STK3/CEBPB/SFRP1/PIM1/FERMT2/ADIRF/KLF5/PPARG/WWTR1/GATA3 10 GO:0034115 negative regulation of heterotypic cell-cell adhesion 3/445 11/18722 0.00190906284182221 0.0373760123202253 KLF4/MYADM/WNK1 3 GO:0034975 protein folding in endoplasmic reticulum 3/445 11/18722 0.00190906284182221 0.0373760123202253 ERO1A/CALR/DNAJC3 3 GO:0036490 regulation of translation in response to endoplasmic reticulum stress 3/445 11/18722 0.00190906284182221 0.0373760123202253 PPP1R15A/EIF2AK4/DNAJC3 3 GO:0045657 positive regulation of monocyte differentiation 3/445 11/18722 0.00190906284182221 0.0373760123202253 CD74/HLA-DRB1/JUN 3 GO:0070587 regulation of cell-cell adhesion involved in gastrulation 3/445 11/18722 0.00190906284182221 0.0373760123202253 KLF4/MYADM/WNK1 3 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway 3/445 11/18722 0.00190906284182221 0.0373760123202253 CPNE1/HSPA1B/LAPTM5 3 GO:0009060 aerobic respiration 12/445 189/18722 0.00193547240229942 0.0377143230844288 BNIP3/UQCR10/UQCRQ/COX6C/COX7C/NDUFB2/RHOA/NDUFA3/COX6A1/NDUFB1/NDUFA4/COX4I1 12 GO:0035994 response to muscle stretch 4/445 23/18722 0.00194797211890771 0.0377796846159989 FOS/CTNNB1/GSN/PIK3CA 4 GO:0002764 immune response-regulating signaling pathway 22/445 468/18722 0.00197143800742892 0.0379321645563526 HLA-DRB1/TYROBP/PAWR/VAV2/RIOK3/FCER1G/PAK2/WNK1/IRF1/HLA-A/HSPA1B/HLA-DPB1/KHDRBS1/PLSCR1/LSM14A/PIK3CA/PLCL2/CTSS/GBP1/LAPTM5/GATA3/NFKBIZ 22 GO:0051348 negative regulation of transferase activity 15/445 268/18722 0.0019741988331193 0.0379321645563526 APOE/SFRP1/TAF7/AIDA/SH3BP5/GSTP1/RPS15/RPL23/PAK2/WNK1/CBL/PPARG/WWTR1/MLLT1/DNAJA1 15 GO:0032355 response to estradiol 10/445 141/18722 0.00201822796505389 0.0381555536414321 WNT7A/SFRP1/CTNNB1/ANXA1/GSTP1/MBD2/TXNIP/HPGD/CALR/NRIP1 10 GO:0051258 protein polymerization 16/445 296/18722 0.0020211067239732 0.0381555536414321 TMSB4X/MYADM/CDC42EP3/HAX1/TMOD3/CENPJ/GOLGA2/KANK4/GSN/HSPA1B/AIF1/CAPZA2/GRB2/RDX/MAP7D3/RHOA 16 GO:0009755 hormone-mediated signaling pathway 12/445 190/18722 0.00202277081759226 0.0381555536414321 SFRP1/TAF7/PMEPA1/SAFB/RXRA/TMF1/THRB/CALR/PPARG/LBH/RHOA/DNAJA1 12 GO:0030041 actin filament polymerization 12/445 190/18722 0.00202277081759226 0.0381555536414321 TMSB4X/MYADM/CDC42EP3/HAX1/TMOD3/KANK4/GSN/AIF1/CAPZA2/GRB2/RDX/RHOA 12 GO:0006413 translational initiation 9/445 118/18722 0.00203473881299193 0.0382068456203166 PPP1R15A/EIF2AK2/EIF1B/EIF4H/EIF2AK4/DENR/KHDRBS1/DNAJC3/ATF4 9 GO:0050821 protein stabilization 12/445 191/18722 0.00211326886701579 0.0395018718988336 STK3/TYROBP/MORC3/PIM1/RPL23/SOX4/HSP90AB1/HSPA1B/CDC37/PLPP3/CALR/CCT6A 12 GO:2000045 regulation of G1/S transition of mitotic cell cycle 10/445 142/18722 0.00212629622593141 0.0395663500419939 KLF4/ANXA1/ADAMTS1/SOX4/PLK2/AIF1/BRD7/RDX/RGCC/WEE1 10 GO:1901216 positive regulation of neuron death 8/445 97/18722 0.00218437123634376 0.0404643179755757 FOS/CTNNB1/TYROBP/JUN/C1QA/MCL1/ATF4/RHOA 8 GO:0002347 response to tumor cell 5/445 39/18722 0.00219414360361388 0.0404643179755757 KLF4/HLA-DRB1/HLA-A/TXNIP/LAPTM5 5 GO:0002831 regulation of response to biotic stimulus 17/445 327/18722 0.00223759181846464 0.0409257080922914 APOE/HLA-B/HLA-DRB1/TYROBP/RIOK3/PAK2/EIF2AK4/SASH1/IRF1/HLA-A/HSP90AB1/PARP14/RPS19/CDC37/PLSCR1/LSM14A/PPARG 17 GO:0030010 establishment of cell polarity 10/445 143/18722 0.00223897604184407 0.0409257080922914 WNT7A/RAP1B/GSN/SHTN1/HSP90AB1/MAP4/RHOA/WEE1/GOLPH3/GATA3 10 GO:0060760 positive regulation of response to cytokine stimulus 6/445 57/18722 0.00227131455961105 0.0410087999696377 CD74/CPNE1/PARP14/HSPA1B/LSM14A/LAPTM5 6 GO:2001233 regulation of apoptotic signaling pathway 18/445 356/18722 0.00227725430625592 0.0410087999696377 CD74/SKIL/STK3/SFRP1/CTNNB1/ING2/S100A9/HMOX1/S100A8/GSTP1/SP100/PAK2/RB1CC1/HSPA1B/MCL1/CTNNA1/TCF7L2/DNAJA1 18 GO:0070663 regulation of leukocyte proliferation 14/445 245/18722 0.0022786149088108 0.0410087999696377 CD74/CEBPB/CTNNB1/HLA-DRB1/TYROBP/ANXA1/PAWR/GSTP1/SLC7A1/HLA-DPA1/IRF1/HLA-A/HLA-DPB1/AIF1 14 GO:0051897 positive regulation of protein kinase B signaling 9/445 120/18722 0.00228323020891229 0.0410087999696377 STK3/HAX1/CPNE1/FERMT2/LRP2/HSP90AB1/PIK3CA/TCF7L2/GATA3 9 GO:0001890 placenta development 10/445 144/18722 0.0023564084779714 0.0421150241830385 KRT19/STK3/CEBPB/KRT8/SPINT1/SPP1/PHLDA2/HSP90AB1/GRB2/PPARG 10 GO:0031668 cellular response to extracellular stimulus 14/445 246/18722 0.00236521075053617 0.0421150241830385 FOS/SFRP1/GABARAP/PIM1/HMOX1/GSTP1/EIF2AK2/JUN/TRIM24/EIF2AK4/CBL/HNRNPA1/AIF1/ATF4 14 GO:1901654 response to ketone 12/445 194/18722 0.002404837241477 0.0426368353842983 FOS/KLF4/SFRP1/SPP1/FOSB/FDX1/GNB1/CBL/TXNIP/SERPINF1/CALR/GOLPH3 12 GO:0043506 regulation of JUN kinase activity 6/445 58/18722 0.00248356364750023 0.0434061192295079 ARHGEF5/SFRP1/AIDA/GSTP1/SASH1/DNAJA1 6 GO:0043525 positive regulation of neuron apoptotic process 6/445 58/18722 0.00248356364750023 0.0434061192295079 CTNNB1/TYROBP/JUN/MCL1/ATF4/RHOA 6 GO:0060996 dendritic spine development 8/445 99/18722 0.00248382309902832 0.0434061192295079 APOE/WNT7A/TANC2/ZMYND8/UBA6/PAK2/MAPK6/PLK2 8 GO:0070586 cell-cell adhesion involved in gastrulation 3/445 12/18722 0.00250076407083584 0.0434061192295079 KLF4/MYADM/WNK1 3 GO:0072182 regulation of nephron tubule epithelial cell differentiation 3/445 12/18722 0.00250076407083584 0.0434061192295079 CTNNB1/WWTR1/GATA3 3 GO:0022408 negative regulation of cell-cell adhesion 12/445 196/18722 0.00261684427456691 0.0450125647896817 KLF4/CD74/MYADM/CEBPB/HLA-DRB1/ANXA1/PAWR/WNK1/IRF1/RDX/RGCC/LAPTM5 12 GO:0031032 actomyosin structure organization 12/445 196/18722 0.00261684427456691 0.0450125647896817 KRT19/TPM1/ARHGEF5/KRT8/SFRP1/CSRP1/TMOD3/FERMT2/PAK2/TJP1/RGCC/RHOA 12 GO:0110020 regulation of actomyosin structure organization 8/445 100/18722 0.00264512171543384 0.0450125647896817 TPM1/ARHGEF5/SFRP1/FERMT2/PAK2/TJP1/RGCC/RHOA 8 GO:0030833 regulation of actin filament polymerization 11/445 171/18722 0.00265944446256132 0.0450125647896817 TMSB4X/MYADM/CDC42EP3/HAX1/TMOD3/KANK4/GSN/CAPZA2/GRB2/RDX/RHOA 11 GO:0042129 regulation of T cell proliferation 11/445 171/18722 0.00265944446256132 0.0450125647896817 CEBPB/CTNNB1/HLA-DRB1/ANXA1/PAWR/SLC7A1/HLA-DPA1/IRF1/HLA-A/HLA-DPB1/AIF1 11 GO:0010560 positive regulation of glycoprotein biosynthetic process 4/445 25/18722 0.00268048679212338 0.0450125647896817 CTNNB1/PAWR/GOLGA2/TCF7L2 4 GO:0032753 positive regulation of interleukin-4 production 4/445 25/18722 0.00268048679212338 0.0450125647896817 CEBPB/FCER1G/SLC7A5/GATA3 4 GO:0032878 regulation of establishment or maintenance of cell polarity 4/445 25/18722 0.00268048679212338 0.0450125647896817 RAP1B/GSN/SHTN1/GATA3 4 GO:0043407 negative regulation of MAP kinase activity 6/445 59/18722 0.00271037290025729 0.0452628355092258 APOE/SFRP1/AIDA/GSTP1/PPARG/DNAJA1 6 GO:0032272 negative regulation of protein polymerization 7/445 79/18722 0.00271961756508382 0.0452628355092258 TMSB4X/MYADM/TMOD3/KANK4/GSN/CAPZA2/RDX 7 GO:1902850 microtubule cytoskeleton organization involved in mitosis 10/445 147/18722 0.00273866462435879 0.0452628355092258 CCSAP/KIF2A/GOLGA2/SBDS/CHMP5/HSPA1B/PLK2/MAP4/LSM14A/RHOA 10 GO:0071560 cellular response to transforming growth factor beta stimulus 14/445 250/18722 0.00273921783522306 0.0452628355092258 FOS/SKIL/WNT7A/SFRP1/FBN2/ING2/JUN/PMEPA1/FERMT2/LIMS1/HSP90AB1/HPGD/PEG10/PPARG 14 GO:0009914 hormone transport 16/445 306/18722 0.00281416877356589 0.0463160605721142 CGA/SFRP1/HLA-DRB1/SPP1/SRI/ANXA1/INHA/SOX4/TMF1/SLC7A5/RAB8B/TCF7L2/GATA3/VAMP8/FAM3B/RAB11FIP1 16 GO:0031099 regeneration 12/445 198/18722 0.00284381781759257 0.0466182992241068 KLF4/WNT7A/CEBPB/SPP1/ANXA1/HMOX1/GSTP1/SRSF5/RPS15/RTN4RL2/KLF5/CTNNA1 12 GO:0050670 regulation of lymphocyte proliferation 13/445 225/18722 0.00293140940163614 0.0478642380954897 CD74/CEBPB/CTNNB1/HLA-DRB1/TYROBP/ANXA1/PAWR/SLC7A1/HLA-DPA1/IRF1/HLA-A/HLA-DPB1/AIF1 13 GO:0016525 negative regulation of angiogenesis 10/445 149/18722 0.00301994780655066 0.0490768078671129 KLF4/CTNNB1/EPN2/ADAMTS1/HSPG2/PLK2/SERPINF1/PPARG/RGCC/SPARC 10 GO:0007584 response to nutrient 11/445 174/18722 0.00304131271217161 0.0490768078671129 SFRP1/SPP1/LDHA/PIM1/HMOX1/GSTP1/TRIM24/PPARG/SRSF2/SPARC/COX4I1 11 GO:0045619 regulation of lymphocyte differentiation 11/445 174/18722 0.00304131271217161 0.0490768078671129 CD74/HLA-DRA/SFRP1/HLA-DRB1/ANXA1/INHA/SOX4/IRF1/RHOA/GATA3/NFKBIZ 11 GO:0014912 negative regulation of smooth muscle cell migration 5/445 42/18722 0.00305862527839168 0.0491641285020857 IGFBP3/TPM1/GSTP1/AIF1/RHOA 5 GO:0022604 regulation of cell morphogenesis 16/445 309/18722 0.00309708447915598 0.0494583421169519 TPM1/MYADM/CDC42EP3/ANXA1/RHOB/CFDP1/FERMT2/PRPF40A/LIMS1/MACF1/CALR/RDX/GBP1/RHOA/SPARC/FMNL2 16 GO:0000422 autophagy of mitochondrion 7/445 81/18722 0.00313325896710297 0.0494583421169519 ATG12/HAX1/GABARAP/BNIP3/BNIP3L/RB1CC1/CDC37 7 GO:0061726 mitochondrion disassembly 7/445 81/18722 0.00313325896710297 0.0494583421169519 ATG12/HAX1/GABARAP/BNIP3/BNIP3L/RB1CC1/CDC37 7 GO:0032944 regulation of mononuclear cell proliferation 13/445 227/18722 0.00316239473936095 0.0494583421169519 CD74/CEBPB/CTNNB1/HLA-DRB1/TYROBP/ANXA1/PAWR/SLC7A1/HLA-DPA1/IRF1/HLA-A/HLA-DPB1/AIF1 13 GO:0001959 regulation of cytokine-mediated signaling pathway 10/445 150/18722 0.0031689779144465 0.0494583421169519 CD74/GSTP1/CPNE1/HSP90AB1/PARP14/HSPA1B/CDC37/LSM14A/PPARG/LAPTM5 10 GO:0022900 electron transport chain 11/445 175/18722 0.00317797701385203 0.0494583421169519 UQCR10/UQCRQ/FDX1/COX6C/COX7C/NDUFB2/NDUFA3/COX6A1/NDUFB1/NDUFA4/COX4I1 11 GO:0045639 positive regulation of myeloid cell differentiation 8/445 103/18722 0.003178529674564 0.0494583421169519 FOS/CA2/CD74/HLA-DRB1/TYROBP/HAX1/JUN/HSPA1B 8 GO:0042541 hemoglobin biosynthetic process 3/445 13/18722 0.00319403171711832 0.0494583421169519 KLF4/INHA/SLC25A37 3 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors 3/445 13/18722 0.00319403171711832 0.0494583421169519 SKIL/STK3/SFRP1 3 GO:0042110 T cell activation 22/445 487/18722 0.00319665392041301 0.0494583421169519 CD74/HLA-DRA/CEBPB/CTNNB1/HLA-DRB1/ANXA1/PAWR/GSN/SLC7A1/FCER1G/SOX4/HLA-DPA1/EIF2AK4/IRF1/HLA-A/HLA-DPB1/AIF1/PIK3CA/RHOA/LAPTM5/GATA3/NFKBIZ 22 GO:0006403 RNA localization 12/445 201/18722 0.00321401646017099 0.0495414253618148 ZNHIT6/NUTF2/IWS1/NUP58/MEX3D/SMG1/YBX1/EIF4A3/YTHDC1/HNRNPA1/KHDRBS1/CCT6A 12 GO:0043254 regulation of protein-containing complex assembly 20/445 427/18722 0.00323129090350088 0.0495712641473569 APOE/TMSB4X/MYADM/CDC42EP3/RAP1B/AIDA/HAX1/TMOD3/EIF2AK2/RIOK3/PMEPA1/KANK4/GSN/FERMT2/HSPA1B/CAPZA2/GRB2/LMO4/RDX/RHOA 20 GO:0007568 aging 17/445 339/18722 0.00323995190505601 0.0495712641473569 FOS/JUND/ING2/MORC3/PAWR/ERO1A/LITAF/JUN/YBX1/LIMS1/MBD2/PLK2/C1QA/SERPINF1/GRB2/CALR/CTNNA1 17 GO:2000181 negative regulation of blood vessel morphogenesis 10/445 151/18722 0.00332380713957302 0.0506264355360915 KLF4/CTNNB1/EPN2/ADAMTS1/HSPG2/PLK2/SERPINF1/PPARG/RGCC/SPARC 10 GO:0001892 embryonic placenta development 7/445 82/18722 0.00335728497874327 0.0506264355360915 KRT19/STK3/CEBPB/KRT8/SPINT1/PHLDA2/GRB2 7 GO:0045621 positive regulation of lymphocyte differentiation 8/445 104/18722 0.00337375148731222 0.0506264355360915 CD74/HLA-DRA/HLA-DRB1/ANXA1/SOX4/RHOA/GATA3/NFKBIZ 8 GO:0046634 regulation of alpha-beta T cell activation 8/445 104/18722 0.00337375148731222 0.0506264355360915 HLA-DRA/HLA-DRB1/ANXA1/IRF1/HLA-A/RHOA/GATA3/NFKBIZ 8 GO:0071559 response to transforming growth factor beta 14/445 256/18722 0.0033903084867661 0.0506264355360915 FOS/SKIL/WNT7A/SFRP1/FBN2/ING2/JUN/PMEPA1/FERMT2/LIMS1/HSP90AB1/HPGD/PEG10/PPARG 14 GO:0061383 trabecula morphogenesis 5/445 43/18722 0.00339470410154862 0.0506264355360915 SFRP1/FBN2/ADAMTS1/FHL2/RHOA 5 GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation 5/445 43/18722 0.00339470410154862 0.0506264355360915 TPM1/HMOX1/GSTP1/PPARG/RHOA 5 GO:1901343 negative regulation of vasculature development 10/445 152/18722 0.00348459296529292 0.0517800487036872 KLF4/CTNNB1/EPN2/ADAMTS1/HSPG2/PLK2/SERPINF1/PPARG/RGCC/SPARC 10 GO:0048678 response to axon injury 7/445 83/18722 0.00359331753467695 0.0530142669133946 KLF4/SPP1/TYROBP/BNIP3/RTN4RL2/AIF1/CTNNA1 7 GO:0050886 endocrine process 7/445 83/18722 0.00359331753467695 0.0530142669133946 CGA/INHA/TMF1/RAB8B/RHOA/GATA3/RAB11FIP1 7 GO:0009266 response to temperature stimulus 11/445 178/18722 0.00361781444696257 0.0531857348057024 FOS/ERO1A/HMOX1/HSPA2/IER5/EIF2AK4/HSP90AB1/HSPA1B/DNAJC3/PDCD6/DNAJA1 11 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 9/445 129/18722 0.00371539849964769 0.0544266354682433 NLRP2/S100A9/S100A8/GSN/CTSD/PPARG/RHOA/LAPTM5/PDCD6 9 GO:0030521 androgen receptor signaling pathway 5/445 44/18722 0.00375652395846879 0.0545810877756291 SFRP1/PMEPA1/TMF1/RHOA/DNAJA1 5 GO:0032233 positive regulation of actin filament bundle assembly 6/445 63/18722 0.00377551630760782 0.0545810877756291 TPM1/ARHGEF5/SFRP1/FERMT2/RGCC/RHOA 6 GO:2000756 regulation of peptidyl-lysine acetylation 6/445 63/18722 0.00377551630760782 0.0545810877756291 TAF7/IWS1/SMARCB1/SOX4/BRD7/GATA3 6 GO:0030038 contractile actin filament bundle assembly 8/445 106/18722 0.00379200488782511 0.0545810877756291 TPM1/ARHGEF5/SFRP1/FERMT2/PAK2/TJP1/RGCC/RHOA 8 GO:0043149 stress fiber assembly 8/445 106/18722 0.00379200488782511 0.0545810877756291 TPM1/ARHGEF5/SFRP1/FERMT2/PAK2/TJP1/RGCC/RHOA 8 GO:0008360 regulation of cell shape 10/445 154/18722 0.00382467365434215 0.0546703351767732 TPM1/CDC42EP3/ANXA1/RHOB/CFDP1/FERMT2/PRPF40A/RDX/RHOA/FMNL2 10 GO:0051168 nuclear export 10/445 154/18722 0.00382467365434215 0.0546703351767732 NUTF2/IWS1/RPS15/SP100/SMG1/YTHDC1/HNRNPA1/KHDRBS1/CALR/TCF7L2 10 GO:0002088 lens development in camera-type eye 7/445 84/18722 0.00384176348252932 0.0547252584356159 SKIL/WNT7A/CTNNB1/VIM/BIRC7/ATF4/GATA3 7 GO:0070307 lens fiber cell development 3/445 14/18722 0.00399399168402948 0.0563111933335351 WNT7A/VIM/ATF4 3 GO:0072160 nephron tubule epithelial cell differentiation 3/445 14/18722 0.00399399168402948 0.0563111933335351 CTNNB1/WWTR1/GATA3 3 GO:0090239 regulation of histone H4 acetylation 3/445 14/18722 0.00399399168402948 0.0563111933335351 TAF7/IWS1/SMARCB1 3 GO:0045670 regulation of osteoclast differentiation 6/445 64/18722 0.0040843924929265 0.0570978863069019 FOS/CA2/CEBPB/SFRP1/CTNNB1/TYROBP 6 GO:0015980 energy derivation by oxidation of organic compounds 16/445 318/18722 0.00409019756190911 0.0570978863069019 PHLDA2/BNIP3/IFNAR1/UQCR10/UQCRQ/RB1CC1/COX6C/PIK3CA/COX7C/NDUFB2/RHOA/NDUFA3/COX6A1/NDUFB1/NDUFA4/COX4I1 16 GO:1903020 positive regulation of glycoprotein metabolic process 4/445 28/18722 0.00410196843899224 0.0570978863069019 CTNNB1/PAWR/GOLGA2/TCF7L2 4 GO:0008361 regulation of cell size 11/445 181/18722 0.00410507679330667 0.0570978863069019 APOE/SPP1/VAV2/SEMA4C/SHTN1/GOLGA4/RB1CC1/HSP90AB1/MACF1/RDX/RHOA 11 GO:0030850 prostate gland development 5/445 45/18722 0.00414515002151414 0.0574617944257547 SFRP1/CTNNB1/ANXA1/SERPINF1/PSAP 5 GO:0006417 regulation of translation 21/445 468/18722 0.0042373035172689 0.0583745367258927 PPP1R15A/VIM/PUM3/NCL/EIF2AK2/EIF1B/MEX3D/SOX4/EIF4H/EIF2AK4/YBX1/DNAJC1/EIF4A3/KHDRBS1/LSM14A/CALR/RBM3/HNRNPR/DNAJC3/ATF4/RHOA 21 GO:2000116 regulation of cysteine-type endopeptidase activity 13/445 235/18722 0.00423925466418974 0.0583745367258927 KLF4/NLRP2/S100A9/S100A8/TNFAIP8/GSN/PAK2/BIRC7/CTSD/PPARG/RHOA/LAPTM5/PDCD6 13 GO:0001503 ossification 19/445 408/18722 0.00430470567534315 0.0590788675908391 OSR2/JUND/CEBPB/SFRP1/FBN2/CTNNB1/SPP1/MRC2/RPS15/RRAS2/SBDS/FERMT2/SRGN/PPARG/FHL2/WWTR1/ATF4/RHOA/SPARC 19 GO:0045667 regulation of osteoblast differentiation 9/445 132/18722 0.00432388605540409 0.0591456069366699 JUND/CEBPB/SFRP1/FBN2/CTNNB1/FERMT2/PPARG/WWTR1/ATF4 9 GO:0071496 cellular response to external stimulus 16/445 320/18722 0.00434303809760806 0.0592115194099633 FOS/SFRP1/GABARAP/PIM1/BNIP3/HMOX1/GSTP1/EIF2AK2/JUN/TRIM24/EIF2AK4/IRF1/CBL/HNRNPA1/AIF1/ATF4 16 GO:0051250 negative regulation of lymphocyte activation 10/445 157/18722 0.00438351125702021 0.0595246025498651 CD74/CEBPB/SFRP1/HLA-DRB1/TYROBP/ANXA1/PAWR/INHA/IRF1/LAPTM5 10 GO:1902905 positive regulation of supramolecular fiber organization 12/445 209/18722 0.00439482057073562 0.0595246025498651 TPM1/APOE/ARHGEF5/SFRP1/CDC42EP3/DSTN/GSN/FERMT2/HSPA1B/GRB2/RGCC/RHOA 12 GO:0046887 positive regulation of hormone secretion 9/445 133/18722 0.00454310685627338 0.0608203586855966 HLA-DRB1/SPP1/SRI/INHA/SOX4/TMF1/RAB8B/TCF7L2/VAMP8 9 GO:0033673 negative regulation of kinase activity 13/445 237/18722 0.00455015938033568 0.0608203586855966 APOE/SFRP1/TAF7/AIDA/SH3BP5/GSTP1/PAK2/WNK1/CBL/PPARG/WWTR1/MLLT1/DNAJA1 13 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle 5/445 46/18722 0.00456164220902155 0.0608203586855966 ANXA1/ADAMTS1/AIF1/RDX/RGCC 5 GO:0045637 regulation of myeloid cell differentiation 12/445 210/18722 0.00456410341141005 0.0608203586855966 FOS/CA2/CD74/CEBPB/SFRP1/CTNNB1/HLA-DRB1/TYROBP/HAX1/INHA/JUN/HSPA1B 12 GO:0050866 negative regulation of cell activation 12/445 210/18722 0.00456410341141005 0.0608203586855966 APOE/CD74/CEBPB/SFRP1/HLA-DRB1/TYROBP/ANXA1/PAWR/INHA/HMOX1/IRF1/LAPTM5 12 GO:0043010 camera-type eye development 16/445 322/18722 0.00460853378286541 0.0612149615981254 OSR2/LPCAT1/KLF4/SKIL/WNT7A/FBN2/CTNNB1/VIM/THRB/HMGN1/GNB1/EFEMP1/BIRC7/SERPINF1/ATF4/GATA3 16 GO:0007051 spindle organization 11/445 184/18722 0.00464327734809958 0.0612478192753796 CCSAP/KIF2A/CENPJ/GOLGA2/SBDS/CHMP5/HSPA1B/PLK2/MAP4/LSM14A/RHOA 11 GO:0019221 cytokine-mediated signaling pathway 21/445 472/18722 0.00466503796152124 0.0612478192753796 CD74/TMSB4X/KRT8/GSTP1/IFNAR1/CPNE1/SP100/FCER1G/LIMS1/WNK1/IRF1/MX1/HSP90AB1/PARP14/CBL/HSPA1B/CDC37/LSM14A/JAK1/PPARG/LAPTM5 21 GO:1901879 regulation of protein depolymerization 7/445 87/18722 0.00466569760216339 0.0612478192753796 LIMA1/DSTN/TMOD3/GSN/CAPZA2/PIK3CA/RDX 7 GO:0001916 positive regulation of T cell mediated cytotoxicity 4/445 29/18722 0.00467031301664114 0.0612478192753796 HLA-B/HLA-DRA/HLA-DRB1/HLA-A 4 GO:0014812 muscle cell migration 8/445 110/18722 0.0047477975049884 0.0618046219398651 IGFBP3/TPM1/ANXA1/GSTP1/ADAMTS1/NET1/AIF1/RHOA 8 GO:1905954 positive regulation of lipid localization 8/445 110/18722 0.0047477975049884 0.0618046219398651 APOE/PLIN2/SPP1/RXRA/TMF1/HILPDA/PPARG/DBI 8 GO:2000573 positive regulation of DNA biosynthetic process 6/445 66/18722 0.00475765426697582 0.0618046219398651 KLF4/CTNNB1/HSP90AB1/HNRNPA1/CCT6A/RGCC 6 GO:0035966 response to topologically incorrect protein 10/445 159/18722 0.00479048776552459 0.0620360657033921 PPP1R15A/ERO1A/HSPA2/EIF2AK2/HSP90AB1/HSPA1B/ERP44/DNAJC3/ATF4/DNAJA1 10 GO:0051896 regulation of protein kinase B signaling 11/445 185/18722 0.00483462011891359 0.0624119240976001 KLF4/STK3/HAX1/CPNE1/FERMT2/LRP2/HSP90AB1/PIK3CA/TCF7L2/GATA3/PDCD6 11 GO:0046879 hormone secretion 15/445 295/18722 0.00485909186869508 0.0625324252634872 CGA/SFRP1/HLA-DRB1/SPP1/SRI/ANXA1/INHA/SOX4/TMF1/RAB8B/TCF7L2/GATA3/VAMP8/FAM3B/RAB11FIP1 15 GO:0002468 dendritic cell antigen processing and presentation 3/445 15/18722 0.0049052282431592 0.0627085408767883 CD74/HLA-DRA/HLA-DRB1 3 GO:0006457 protein folding 12/445 212/18722 0.00491831693151281 0.0627085408767883 CD74/ERO1A/HSPA2/DNAJC1/HSP90AB1/HSPA1B/CDC37/ERP44/CALR/DNAJC3/CCT6A/DNAJA1 12 GO:0006469 negative regulation of protein kinase activity 12/445 212/18722 0.00491831693151281 0.0627085408767883 APOE/SFRP1/TAF7/AIDA/SH3BP5/GSTP1/PAK2/CBL/PPARG/WWTR1/MLLT1/DNAJA1 12 GO:0001843 neural tube closure 7/445 88/18722 0.00496792657202792 0.063031935601965 MTHFD1L/SFRP1/SPINT1/SEMA4C/BRD2/LRP2/LMO4 7 GO:0016055 Wnt signaling pathway 20/445 444/18722 0.00497419777444701 0.063031935601965 APOE/KLF4/STK3/WNT7A/SFRP1/CTNNB1/RNF213/RPS12/FERMT2/SOX4/WNK1/MBD2/PLPP3/MACF1/RTF1/WWTR1/BRD7/RHOA/TCF7L2/GATA3 20 GO:0090288 negative regulation of cellular response to growth factor stimulus 8/445 111/18722 0.00501330280513669 0.063333192318103 SKIL/SFRP1/EPN2/UBE2D1/LRP2/PPARG/GATA3/PDCD6 8 GO:0046635 positive regulation of alpha-beta T cell activation 6/445 67/18722 0.00512330399330826 0.0640853148627697 HLA-DRA/HLA-DRB1/ANXA1/HLA-A/RHOA/NFKBIZ 6 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 17/445 355/18722 0.00512991560165637 0.0640853148627697 FOS/SKIL/SFRP1/FBN2/ING2/VIM/INHA/JUN/UBE2D1/PMEPA1/FERMT2/LRP2/HSP90AB1/HPGD/PEG10/PPARG/WWTR1 17 GO:0016032 viral process 19/445 415/18722 0.00515244772289469 0.0640853148627697 APOE/CD74/HLA-DRB1/SMARCB1/EIF2AK2/JUN/GALNT1/GSN/RXRA/CTBP2/EIF2AK4/CHMP5/MX1/HSP90AB1/DENR/HSPA1B/PLSCR1/RSF1/VAMP8 19 GO:0198738 cell-cell signaling by wnt 20/445 446/18722 0.00522256017394813 0.0640853148627697 APOE/KLF4/STK3/WNT7A/SFRP1/CTNNB1/RNF213/RPS12/FERMT2/SOX4/WNK1/MBD2/PLPP3/MACF1/RTF1/WWTR1/BRD7/RHOA/TCF7L2/GATA3 20 GO:0003205 cardiac chamber development 10/445 161/18722 0.00522658441311334 0.0640853148627697 TPM1/LUZP1/ADAMTS1/SOX4/PKP2/LRP2/FHL2/LMO4/DSP/GATA3 10 GO:0036294 cellular response to decreased oxygen levels 10/445 161/18722 0.00522658441311334 0.0640853148627697 SFRP1/ERO1A/BNIP3/HMOX1/BNIP3L/NDRG1/GNB1/CBL/HILPDA/RGCC 10 GO:0002695 negative regulation of leukocyte activation 11/445 187/18722 0.00523603766175872 0.0640853148627697 CD74/CEBPB/SFRP1/HLA-DRB1/TYROBP/ANXA1/PAWR/INHA/HMOX1/IRF1/LAPTM5 11 GO:0045727 positive regulation of translation 9/445 136/18722 0.00525301036043319 0.0640853148627697 PPP1R15A/VIM/SOX4/EIF2AK4/EIF4A3/KHDRBS1/RBM3/DNAJC3/RHOA 9 GO:0060606 tube closure 7/445 89/18722 0.00528464603156404 0.0640853148627697 MTHFD1L/SFRP1/SPINT1/SEMA4C/BRD2/LRP2/LMO4 7 GO:0045948 positive regulation of translational initiation 4/445 30/18722 0.0052892804863772 0.0640853148627697 PPP1R15A/EIF2AK4/KHDRBS1/DNAJC3 4 GO:0048147 negative regulation of fibroblast proliferation 4/445 30/18722 0.0052892804863772 0.0640853148627697 SFRP1/MORC3/PAWR/GSTP1 4 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway 4/445 30/18722 0.0052892804863772 0.0640853148627697 PAWR/PLCL2/GBP1/LAPTM5 4 GO:0032609 interferon-gamma production 8/445 112/18722 0.00529002478049006 0.0640853148627697 HLA-DRB1/INHA/HLA-DPA1/HLA-A/HLA-DPB1/SLC7A5/LAPTM5/GATA3 8 GO:0032649 regulation of interferon-gamma production 8/445 112/18722 0.00529002478049006 0.0640853148627697 HLA-DRB1/INHA/HLA-DPA1/HLA-A/HLA-DPB1/SLC7A5/LAPTM5/GATA3 8 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 5/445 48/18722 0.00548242767192353 0.0662219553003394 SKIL/STK3/SFRP1/PAK2/CTNNA1 5 GO:0046637 regulation of alpha-beta T cell differentiation 6/445 68/18722 0.00550914299936596 0.066350640613355 HLA-DRA/HLA-DRB1/ANXA1/RHOA/GATA3/NFKBIZ 6 GO:0034109 homotypic cell-cell adhesion 7/445 90/18722 0.00561627765572423 0.067444311034293 CSRP1/PKP2/PLPP3/JAK1/RDX/DSP/HBB 7 GO:0009612 response to mechanical stimulus 12/445 216/18722 0.00569248151664997 0.068161278681974 FOS/JUND/CTNNB1/BNIP3/JUN/FOSB/GSN/IRF1/MBD2/TXNIP/PIK3CA/RHOA 12 GO:0071900 regulation of protein serine/threonine kinase activity 17/445 359/18722 0.00572179348443456 0.0683142453300553 APOE/STK3/ARHGEF5/SFRP1/CCNL1/AIDA/GSTP1/CCNG2/FERMT2/SASH1/HSP90AB1/CDC37/PPARG/RGCC/RHOA/CCNI/DNAJA1 17 GO:0006913 nucleocytoplasmic transport 15/445 301/18722 0.00582659567759137 0.0691657090348562 NUTF2/IWS1/NUP58/HTATIP2/RPS15/RPL23/SP100/SMG1/HSP90AB1/YTHDC1/HNRNPA1/TXNIP/KHDRBS1/CALR/TCF7L2 15 GO:0051169 nuclear transport 15/445 301/18722 0.00582659567759137 0.0691657090348562 NUTF2/IWS1/NUP58/HTATIP2/RPS15/RPL23/SP100/SMG1/HSP90AB1/YTHDC1/HNRNPA1/TXNIP/KHDRBS1/CALR/TCF7L2 15 GO:0002286 T cell activation involved in immune response 8/445 114/18722 0.00587832148680848 0.0691686777658862 CD74/HLA-DRA/HLA-DRB1/ANXA1/FCER1G/EIF2AK4/GATA3/NFKBIZ 8 GO:0045669 positive regulation of osteoblast differentiation 6/445 69/18722 0.00591580322431723 0.0691686777658862 JUND/CEBPB/FBN2/CTNNB1/FERMT2/WWTR1 6 GO:1901224 positive regulation of NIK/NF-kappaB signaling 6/445 69/18722 0.00591580322431723 0.0691686777658862 EIF2AK2/LIMS1/SASH1/CALR/RHOA/LAPTM5 6 GO:0032274 gonadotropin secretion 3/445 16/18722 0.00593181243536848 0.0691686777658862 CGA/INHA/TMF1 3 GO:0097284 hepatocyte apoptotic process 3/445 16/18722 0.00593181243536848 0.0691686777658862 STK3/KRT8/GSN 3 GO:2001044 regulation of integrin-mediated signaling pathway 3/445 16/18722 0.00593181243536848 0.0691686777658862 LIMS1/CD63/CTNNA1 3 GO:0048384 retinoic acid receptor signaling pathway 4/445 31/18722 0.00596079624416739 0.0691686777658862 RXRA/CTBP2/CALR/PPARG 4 GO:0060795 cell fate commitment involved in formation of primary germ layer 4/445 31/18722 0.00596079624416739 0.0691686777658862 KLF4/CTNNB1/ETS2/RTF1 4 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors 5/445 49/18722 0.00598879868333475 0.0692989561928736 SKIL/STK3/SFRP1/HMOX1/SP100 5 GO:0007163 establishment or maintenance of cell polarity 12/445 218/18722 0.00611426506846363 0.0705531536252047 WNT7A/RAP1B/RHOB/GSN/SHTN1/HSP90AB1/MAP4/CTNNA1/RHOA/WEE1/GOLPH3/GATA3 12 GO:0046661 male sex differentiation 10/445 165/18722 0.00619170138871256 0.0712476836678875 SFRP1/CTNNB1/ING2/INHA/FNDC3A/TMF1/LRP2/CBL/CTNNA1/GATA3 10 GO:0032872 regulation of stress-activated MAPK cascade 11/445 192/18722 0.00635536463384176 0.072842579749274 PAGE4/STK3/WNT7A/SFRP1/AIDA/SEMA4C/GSTP1/EIF2AK2/SASH1/RB1CC1/DNAJA1 11 GO:0090287 regulation of cellular response to growth factor stimulus 15/445 304/18722 0.0063655703920329 0.072842579749274 SKIL/SFRP1/FBN2/CTNNB1/ING2/EPN2/UBE2D1/PMEPA1/LRP2/HSP90AB1/CD63/PEG10/PPARG/GATA3/PDCD6 15 GO:0031098 stress-activated protein kinase signaling cascade 13/445 247/18722 0.00639141387083597 0.0729362726531033 PAGE4/STK3/WNT7A/SFRP1/AIDA/SEMA4C/GSTP1/EIF2AK2/SH2D3A/SASH1/RB1CC1/RHOA/DNAJA1 13 GO:1990748 cellular detoxification 8/445 116/18722 0.00651510841138748 0.073860955169144 APOE/HBA2/S100A9/HBA1/PIM1/HBG2/GSTP1/HBB 8 GO:0046638 positive regulation of alpha-beta T cell differentiation 5/445 50/18722 0.00652718800350826 0.073860955169144 HLA-DRA/HLA-DRB1/ANXA1/RHOA/NFKBIZ 5 GO:2000677 regulation of transcription regulatory region DNA binding 5/445 50/18722 0.00652718800350826 0.073860955169144 KLF4/TMSB4X/CTNNB1/SRI/GATA3 5 GO:0022618 ribonucleoprotein complex assembly 12/445 220/18722 0.00656042860254191 0.073860955169144 SFSWAP/ZNHIT6/SRSF5/RPS15/SCAF11/EIF4H/HSP90AB1/RPS19/DENR/YTHDC1/SRSF9/RPS28 12 GO:0008584 male gonad development 9/445 141/18722 0.0066237700645155 0.073860955169144 SFRP1/ING2/INHA/FNDC3A/TMF1/LRP2/CBL/CTNNA1/GATA3 9 GO:1903038 negative regulation of leukocyte cell-cell adhesion 9/445 141/18722 0.0066237700645155 0.073860955169144 KLF4/CD74/CEBPB/HLA-DRB1/ANXA1/PAWR/WNK1/IRF1/LAPTM5 9 GO:0033687 osteoblast proliferation 4/445 32/18722 0.0066867186513798 0.073860955169144 OSR2/SFRP1/EIF2AK2/RHOA 4 GO:0042744 hydrogen peroxide catabolic process 4/445 32/18722 0.0066867186513798 0.073860955169144 HBA2/HBA1/HBG2/HBB 4 GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation 4/445 32/18722 0.0066867186513798 0.073860955169144 HLA-DRA/HLA-DRB1/ANXA1/NFKBIZ 4 GO:0033273 response to vitamin 7/445 93/18722 0.00670487973576107 0.073860955169144 SFRP1/SPP1/PIM1/GSTP1/TRIM24/SRSF2/SPARC 7 GO:0051591 response to cAMP 7/445 93/18722 0.00670487973576107 0.073860955169144 FOS/RAP1B/LDHA/JUN/FOSB/FDX1/SPARC 7 GO:0097306 cellular response to alcohol 7/445 93/18722 0.00670487973576107 0.073860955169144 KLF4/SFRP1/CTNNB1/FDX1/GNB1/CTNNA1/GOLPH3 7 GO:1901992 positive regulation of mitotic cell cycle phase transition 7/445 93/18722 0.00670487973576107 0.073860955169144 ANXA1/HSPA2/TMOD3/ADAMTS1/AIF1/RDX/RGCC 7 GO:0046034 ATP metabolic process 14/445 277/18722 0.00673141980226678 0.0739561042637343 TMSB4X/LDHA/UQCR10/UQCRQ/HSPA1B/COX6C/COX7C/NDUFB2/RHOA/NDUFA3/COX6A1/NDUFB1/NDUFA4/COX4I1 14 GO:0003208 cardiac ventricle morphogenesis 6/445 71/18722 0.00679410774016489 0.0744468410467405 TPM1/SOX4/PKP2/LRP2/DSP/GATA3 6 GO:0046546 development of primary male sexual characteristics 9/445 142/18722 0.00692811039945727 0.0757143493654973 SFRP1/ING2/INHA/FNDC3A/TMF1/LRP2/CBL/CTNNA1/GATA3 9 GO:1902806 regulation of cell cycle G1/S phase transition 10/445 168/18722 0.0070024337803512 0.0761137189357386 KLF4/ANXA1/ADAMTS1/SOX4/PLK2/AIF1/BRD7/RDX/RGCC/WEE1 10 GO:0016045 detection of bacterium 3/445 17/18722 0.00707732930155415 0.0761137189357386 HLA-B/HLA-DRB1/HLA-A 3 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 3/445 17/18722 0.00707732930155415 0.0761137189357386 HLA-B/HLA-C/HLA-A 3 GO:0020027 hemoglobin metabolic process 3/445 17/18722 0.00707732930155415 0.0761137189357386 KLF4/INHA/SLC25A37 3 GO:0097067 cellular response to thyroid hormone stimulus 3/445 17/18722 0.00707732930155415 0.0761137189357386 THRB/CTSS/RDX 3 GO:2000696 regulation of epithelial cell differentiation involved in kidney development 3/445 17/18722 0.00707732930155415 0.0761137189357386 CTNNB1/WWTR1/GATA3 3 GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation 5/445 51/18722 0.00709860359005283 0.0761137189357386 HLA-DRA/HLA-DRB1/ANXA1/GATA3/NFKBIZ 5 GO:0070302 regulation of stress-activated protein kinase signaling cascade 11/445 195/18722 0.00711205410534861 0.0761137189357386 PAGE4/STK3/WNT7A/SFRP1/AIDA/SEMA4C/GSTP1/EIF2AK2/SASH1/RB1CC1/DNAJA1 11 GO:0038061 NIK/NF-kappaB signaling 9/445 143/18722 0.00724305225929694 0.07713929879287 TMSB4X/LITAF/EIF2AK2/CPNE1/LIMS1/SASH1/CALR/RHOA/LAPTM5 9 GO:0001655 urogenital system development 16/445 338/18722 0.00724523067819742 0.07713929879287 OSR2/CA2/SFRP1/CTNNB1/ANXA1/ADAMTS1/SOX4/BASP1/LRP2/IRX2/SERPINF1/HPGD/WWTR1/RHOA/GATA3/PSAP 16 GO:1901880 negative regulation of protein depolymerization 6/445 72/18722 0.00726700647510097 0.0771722461404682 LIMA1/TMOD3/GSN/CAPZA2/PIK3CA/RDX 6 GO:0046685 response to arsenic-containing substance 4/445 33/18722 0.00746883605935201 0.0789098766270669 HMOX1/HNRNPA1/SERPINF1/ATF4 4 GO:0071353 cellular response to interleukin-4 4/445 33/18722 0.00746883605935201 0.0789098766270669 NFIL3/HSP90AB1/PARP14/GATA3 4 GO:0010718 positive regulation of epithelial to mesenchymal transition 5/445 52/18722 0.00770403829590911 0.0809806162860064 CTNNB1/FERMT2/WWTR1/RGCC/TCF7L2 5 GO:0030514 negative regulation of BMP signaling pathway 5/445 52/18722 0.00770403829590911 0.0809806162860064 SKIL/SFRP1/UBE2D1/LRP2/PPARG 5 GO:0009743 response to carbohydrate 13/445 253/18722 0.00775342858996605 0.0812929276780451 HLA-DRB1/RAP1B/SRI/LDHA/GSTP1/SMARCB1/SOX4/TXNIP/SERPINF1/PIK3CA/RHOA/SPARC/TCF7L2 13 GO:0034284 response to monosaccharide 12/445 225/18722 0.00778877187931778 0.0814567509707892 HLA-DRB1/SRI/LDHA/GSTP1/SMARCB1/SOX4/TXNIP/SERPINF1/PIK3CA/RHOA/SPARC/TCF7L2 12 GO:0051048 negative regulation of secretion 10/445 171/18722 0.00789306597971287 0.0823390291974593 APOE/CD74/SFRP1/RAP1B/ANXA1/INHA/HMOX1/WNK1/VAMP8/RAB11FIP1 10 GO:0007179 transforming growth factor beta receptor signaling pathway 11/445 198/18722 0.00793736641171956 0.0824431109561635 FOS/SKIL/FBN2/ING2/JUN/PMEPA1/FERMT2/HSP90AB1/HPGD/PEG10/PPARG 11 GO:1901655 cellular response to ketone 7/445 96/18722 0.00794295767624136 0.0824431109561635 KLF4/SFRP1/SPP1/FDX1/GNB1/SERPINF1/GOLPH3 7 GO:0042098 T cell proliferation 11/445 199/18722 0.00822841070237678 0.0833235384223368 CEBPB/CTNNB1/HLA-DRB1/ANXA1/PAWR/SLC7A1/HLA-DPA1/IRF1/HLA-A/HLA-DPB1/AIF1 11 GO:0007043 cell-cell junction assembly 9/445 146/18722 0.00825381952117603 0.0833235384223368 CTNNB1/PKP3/PKP2/CLDN7/PAK2/TJP1/CLDN19/CTNNA1/RHOA 9 GO:0045580 regulation of T cell differentiation 9/445 146/18722 0.00825381952117603 0.0833235384223368 CD74/HLA-DRA/HLA-DRB1/ANXA1/SOX4/IRF1/RHOA/GATA3/NFKBIZ 9 GO:0032496 response to lipopolysaccharide 16/445 343/18722 0.00828132614549633 0.0833235384223368 FOS/JUND/CEBPB/VIM/S100A9/S100A8/LITAF/GSTP1/JUN/IFNAR1/SASH1/CHMP5/AKAP12/HPGD/RHOA/SPARC 16 GO:0006356 regulation of transcription by RNA polymerase I 4/445 34/18722 0.0083088642206632 0.0833235384223368 POLR2L/NCL/SMARCB1/ATF4 4 GO:0051085 chaperone cofactor-dependent protein refolding 4/445 34/18722 0.0083088642206632 0.0833235384223368 CD74/ERO1A/HSPA2/HSPA1B 4 GO:2000758 positive regulation of peptidyl-lysine acetylation 4/445 34/18722 0.0083088642206632 0.0833235384223368 SMARCB1/SOX4/BRD7/GATA3 4 GO:0071826 ribonucleoprotein complex subunit organization 12/445 227/18722 0.00832783412838046 0.0833235384223368 SFSWAP/ZNHIT6/SRSF5/RPS15/SCAF11/EIF4H/HSP90AB1/RPS19/DENR/YTHDC1/SRSF9/RPS28 12 GO:0003206 cardiac chamber morphogenesis 8/445 121/18722 0.0083352755373239 0.0833235384223368 TPM1/ADAMTS1/SOX4/PKP2/LRP2/FHL2/DSP/GATA3 8 GO:0043244 regulation of protein-containing complex disassembly 8/445 121/18722 0.0083352755373239 0.0833235384223368 LIMA1/DSTN/BNIP3/TMOD3/GSN/CAPZA2/PIK3CA/RDX 8 GO:1904019 epithelial cell apoptotic process 8/445 121/18722 0.0083352755373239 0.0833235384223368 STK3/KRT8/HMOX1/GSN/ANGPTL4/RGCC/TCF7L2/GATA3 8 GO:0030728 ovulation 3/445 18/18722 0.00834490398554782 0.0833235384223368 ADAMTS1/HPGD/NRIP1 3 GO:0060192 negative regulation of lipase activity 3/445 18/18722 0.00834490398554782 0.0833235384223368 APOC1/ANXA1/ANGPTL4 3 GO:0072079 nephron tubule formation 3/445 18/18722 0.00834490398554782 0.0833235384223368 CTNNB1/IRX2/GATA3 3 GO:1901673 regulation of mitotic spindle assembly 3/445 18/18722 0.00834490398554782 0.0833235384223368 CCSAP/CHMP5/HSPA1B 3 GO:0010596 negative regulation of endothelial cell migration 7/445 97/18722 0.00839084773267783 0.0833235384223368 APOE/KLF4/SP100/SERPINF1/PPARG/RGCC/RHOA 7 GO:0070252 actin-mediated cell contraction 7/445 97/18722 0.00839084773267783 0.0833235384223368 TPM1/SRI/GSN/SHTN1/PKP2/PIK3CA/DSP 7 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 7/445 97/18722 0.00839084773267783 0.0833235384223368 HMOX1/GSTP1/RB1CC1/HSPA1B/MCL1/CTNNA1/TCF7L2 7 GO:0030098 lymphocyte differentiation 17/445 374/18722 0.00845569402135761 0.0837661199094204 CD74/HLA-DRA/SFRP1/CTNNB1/HLA-DRB1/ANXA1/INHA/FCER1G/SOX4/KLF6/TPD52/NFIL3/IRF1/PLCL2/RHOA/GATA3/NFKBIZ 17 GO:0034976 response to endoplasmic reticulum stress 13/445 256/18722 0.00851538630537241 0.0841556479126637 CEBPB/PPP1R15A/ERO1A/EIF2AK2/JUN/EIF2AK4/MAN1A1/ERP44/CALR/DNAJC3/ATF4/UBE2J1/UFC1 13 GO:0150063 visual system development 17/445 375/18722 0.0086698847803843 0.0854780287058892 OSR2/LPCAT1/KLF4/SKIL/WNT7A/FBN2/CTNNB1/VIM/THRB/HMGN1/GNB1/EFEMP1/BIRC7/C1QA/SERPINF1/ATF4/GATA3 17 GO:0002292 T cell differentiation involved in immune response 6/445 75/18722 0.00882814397249037 0.086831101786566 HLA-DRA/HLA-DRB1/ANXA1/FCER1G/GATA3/NFKBIZ 6 GO:2001056 positive regulation of cysteine-type endopeptidase activity 9/445 148/18722 0.00898496023116911 0.0881635883965786 NLRP2/S100A9/S100A8/GSN/CTSD/PPARG/RHOA/LAPTM5/PDCD6 9 GO:0035065 regulation of histone acetylation 5/445 54/18722 0.00902085248204771 0.0882245397935655 TAF7/IWS1/SMARCB1/BRD7/GATA3 5 GO:0031348 negative regulation of defense response 13/445 258/18722 0.00905524204126647 0.0882245397935655 APOE/KLF4/HLA-B/HLA-DRB1/GSTP1/RIOK3/HLA-A/PARP14/RPS19/PLK2/SERPINF1/PPARG/GATA3 13 GO:0045165 cell fate commitment 13/445 258/18722 0.00905524204126647 0.0882245397935655 KLF4/IFRD1/WNT7A/SFRP1/CTNNB1/ETS2/MCL1/RTF1/PPARG/LMO4/RHOA/TCF7L2/GATA3 13 GO:0003231 cardiac ventricle development 8/445 123/18722 0.0091610840315145 0.0888786972582561 TPM1/LUZP1/SOX4/PKP2/LRP2/LMO4/DSP/GATA3 8 GO:0010639 negative regulation of organelle organization 16/445 347/18722 0.00919277248991916 0.0888786972582561 TMSB4X/MYADM/LIMA1/BNIP3/TMOD3/KANK4/GSN/PAK2/ODF2L/HNRNPA1/MAP4/CAPZA2/TJP1/PIK3CA/PPARG/RDX 16 GO:0033280 response to vitamin D 4/445 35/18722 0.00920844406355208 0.0888786972582561 SFRP1/SPP1/PIM1/TRIM24 4 GO:0097421 liver regeneration 4/445 35/18722 0.00920844406355208 0.0888786972582561 CEBPB/HMOX1/SRSF5/RPS15 4 GO:0046651 lymphocyte proliferation 14/445 288/18722 0.00931882653545158 0.0895397641993202 CD74/CEBPB/CTNNB1/HLA-DRB1/TYROBP/ANXA1/PAWR/SLC7A1/HLA-DPA1/IRF1/HLA-A/HLA-DPB1/AIF1/PLCL2 14 GO:0010717 regulation of epithelial to mesenchymal transition 7/445 99/18722 0.00934196038971363 0.0895397641993202 SFRP1/CTNNB1/FERMT2/WWTR1/RGCC/TCF7L2/GATA3 7 GO:0033209 tumor necrosis factor-mediated signaling pathway 7/445 99/18722 0.00934196038971363 0.0895397641993202 TMSB4X/KRT8/GSTP1/CPNE1/LIMS1/HSPA1B/LAPTM5 7 GO:0051592 response to calcium ion 9/445 149/18722 0.00936842531560888 0.0895855670805099 FOS/JUND/SLC25A24/FOSB/CPNE1/WNK1/TXNIP/SPARC/PDCD6 9 GO:0070661 leukocyte proliferation 15/445 318/18722 0.00943450068117426 0.0900090584617341 CD74/CEBPB/CTNNB1/HLA-DRB1/TYROBP/ANXA1/PAWR/GSTP1/SLC7A1/HLA-DPA1/IRF1/HLA-A/HLA-DPB1/AIF1/PLCL2 15 GO:0097237 cellular response to toxic substance 8/445 124/18722 0.00959616608303174 0.0913404656428666 APOE/HBA2/S100A9/HBA1/PIM1/HBG2/GSTP1/HBB 8 GO:0045620 negative regulation of lymphocyte differentiation 5/445 55/18722 0.00973412966523506 0.0922579901487127 CD74/SFRP1/ANXA1/INHA/IRF1 5 GO:0000028 ribosomal small subunit assembly 3/445 19/18722 0.00973722675014252 0.0922579901487127 RPS15/RPS19/RPS28 3 GO:0032271 regulation of protein polymerization 12/445 232/18722 0.00980346086178036 0.0926729904348161 TMSB4X/MYADM/CDC42EP3/HAX1/TMOD3/KANK4/GSN/HSPA1B/CAPZA2/GRB2/RDX/RHOA 12 GO:0071453 cellular response to oxygen levels 10/445 177/18722 0.00993390316316475 0.093691675723821 SFRP1/ERO1A/BNIP3/HMOX1/BNIP3L/NDRG1/GNB1/CBL/HILPDA/RGCC 10 GO:1901983 regulation of protein acetylation 6/445 77/18722 0.00999372445366339 0.0940411747564544 TAF7/IWS1/SMARCB1/SOX4/BRD7/GATA3 6 GO:0048880 sensory system development 17/445 381/18722 0.0100480258515659 0.0942194450948983 OSR2/LPCAT1/KLF4/SKIL/WNT7A/FBN2/CTNNB1/VIM/THRB/HMGN1/GNB1/EFEMP1/BIRC7/C1QA/SERPINF1/ATF4/GATA3 17 GO:0032943 mononuclear cell proliferation 14/445 291/18722 0.0101455057241145 0.0942194450948983 CD74/CEBPB/CTNNB1/HLA-DRB1/TYROBP/ANXA1/PAWR/SLC7A1/HLA-DPA1/IRF1/HLA-A/HLA-DPB1/AIF1/PLCL2 14 GO:0030224 monocyte differentiation 4/445 36/18722 0.010169139807029 0.0942194450948983 CD74/HLA-DRB1/JUN/PPARG 4 GO:0070306 lens fiber cell differentiation 4/445 36/18722 0.010169139807029 0.0942194450948983 SKIL/WNT7A/VIM/ATF4 4 GO:0070670 response to interleukin-4 4/445 36/18722 0.010169139807029 0.0942194450948983 NFIL3/HSP90AB1/PARP14/GATA3 4 GO:0043535 regulation of blood vessel endothelial cell migration 9/445 151/18722 0.0101723245006838 0.0942194450948983 APOE/KLF4/TMSB4X/ANXA1/HMOX1/PLK2/PPARG/RGCC/RHOA 9 GO:0071456 cellular response to hypoxia 9/445 151/18722 0.0101723245006838 0.0942194450948983 SFRP1/ERO1A/BNIP3/HMOX1/BNIP3L/NDRG1/GNB1/HILPDA/RGCC 9 GO:0098869 cellular oxidant detoxification 7/445 101/18722 0.0103696482768595 0.095618341588631 APOE/HBA2/S100A9/HBA1/HBG2/GSTP1/HBB 7 GO:0150115 cell-substrate junction organization 7/445 101/18722 0.0103696482768595 0.095618341588631 SFRP1/FERMT2/LIMS1/COL17A1/MACF1/RAB8B/RHOA 7 GO:0010975 regulation of neuron projection development 19/445 445/18722 0.0104785321859925 0.0960408848984542 APOE/KLF4/SKIL/WNT7A/SFRP1/VIM/SPP1/S100A9/SEMA4C/TANC2/SHTN1/GOLGA4/RTN4RL2/PAK2/UBE2V2/SERPINF1/MACF1/RHOA/GATA3 19 GO:0001912 positive regulation of leukocyte mediated cytotoxicity 5/445 56/18722 0.0104852188548058 0.0960408848984542 HLA-B/HLA-DRA/HLA-DRB1/TYROBP/HLA-A 5 GO:0002711 positive regulation of T cell mediated immunity 5/445 56/18722 0.0104852188548058 0.0960408848984542 HLA-B/HLA-DRA/HLA-DRB1/HLA-A/GATA3 5 GO:2001235 positive regulation of apoptotic signaling pathway 8/445 126/18722 0.0105122245265238 0.0960752201749333 SKIL/STK3/SFRP1/S100A9/S100A8/PAK2/MCL1/CTNNA1 8 GO:0098754 detoxification 9/445 152/18722 0.0105932306812328 0.0965941312270611 APOE/HBA2/S100A9/HBA1/PIM1/HBG2/GSTP1/MT2A/HBB 9 GO:0043297 apical junction assembly 6/445 78/18722 0.0106157675083722 0.0965941312270611 CLDN7/PAK2/TJP1/CLDN19/CTNNA1/RHOA 6 GO:0001822 kidney development 14/445 293/18722 0.0107278617689619 0.0973995537749044 OSR2/CA2/SFRP1/CTNNB1/ADAMTS1/SOX4/BASP1/LRP2/IRX2/SERPINF1/HPGD/WWTR1/RHOA/GATA3 14 GO:1901215 negative regulation of neuron death 11/445 208/18722 0.0112358099145752 0.100598480887847 APOE/CEBPB/CTNNB1/HMOX1/UBE2V2/HSP90AB1/CBL/SERPINF1/PIK3CA/ATF4/RHOA 11 GO:0003159 morphogenesis of an endothelium 3/445 20/18722 0.0112565769458677 0.100598480887847 CTNNB1/RHOB/RHOA 3 GO:0048025 negative regulation of mRNA splicing, via spliceosome 3/445 20/18722 0.0112565769458677 0.100598480887847 SFSWAP/SRSF4/SRSF9 3 GO:0060231 mesenchymal to epithelial transition 3/445 20/18722 0.0112565769458677 0.100598480887847 CTNNB1/BASP1/GATA3 3 GO:0061154 endothelial tube morphogenesis 3/445 20/18722 0.0112565769458677 0.100598480887847 CTNNB1/RHOB/RHOA 3 GO:0071243 cellular response to arsenic-containing substance 3/445 20/18722 0.0112565769458677 0.100598480887847 HMOX1/HNRNPA1/ATF4 3 GO:0098543 detection of other organism 3/445 20/18722 0.0112565769458677 0.100598480887847 HLA-B/HLA-DRB1/HLA-A 3 GO:1900024 regulation of substrate adhesion-dependent cell spreading 5/445 57/18722 0.0112750173447284 0.100598480887847 MYADM/FERMT2/LIMS1/CALR/GBP1 5 GO:0060562 epithelial tube morphogenesis 15/445 325/18722 0.0113561486005802 0.101103986786631 MTHFD1L/STK3/LUZP1/SFRP1/CTNNB1/SPINT1/SEMA4C/BRD2/RHOB/SOX4/LRP2/IRX2/LMO4/RHOA/GATA3 15 GO:0001818 negative regulation of cytokine production 16/445 357/18722 0.011823043143003 0.105034389728484 KLF4/TMSB4X/HLA-DRB1/NUTF2/TYROBP/ANXA1/INHA/HMOX1/GSTP1/ANXA4/HSP90AB1/SRGN/GBP1/RGCC/LAPTM5/GATA3 16 GO:0034614 cellular response to reactive oxygen species 9/445 155/18722 0.0119346054327211 0.105630651781091 FOS/TPM1/KLF4/ANXA1/PAWR/BNIP3/RHOB/JUN/NET1 9 GO:0048145 regulation of fibroblast proliferation 6/445 80/18722 0.0119413009880826 0.105630651781091 CD74/SFRP1/CTNNB1/MORC3/PAWR/GSTP1 6 GO:1902808 positive regulation of cell cycle G1/S phase transition 5/445 58/18722 0.0121043997689952 0.106844605653246 ANXA1/ADAMTS1/AIF1/RDX/RGCC 5 GO:0051403 stress-activated MAPK cascade 12/445 239/18722 0.0122011703420964 0.107410232869223 PAGE4/STK3/WNT7A/SFRP1/AIDA/SEMA4C/GSTP1/EIF2AK2/SH2D3A/SASH1/RB1CC1/DNAJA1 12 GO:0032717 negative regulation of interleukin-8 production 4/445 38/18722 0.0122797432310649 0.107410232869223 KLF4/TMSB4X/ANXA1/ANXA4 4 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway 4/445 38/18722 0.0122797432310649 0.107410232869223 SFRP1/CALR/LBH/RHOA 4 GO:0046329 negative regulation of JNK cascade 4/445 38/18722 0.0122797432310649 0.107410232869223 SFRP1/AIDA/GSTP1/DNAJA1 4 GO:0031647 regulation of protein stability 14/445 298/18722 0.0122984846640383 0.107410232869223 STK3/TYROBP/MORC3/PIM1/TRIM24/RPL23/GSN/SOX4/HSP90AB1/HSPA1B/CDC37/PLPP3/CALR/CCT6A 14 GO:0043491 protein kinase B signaling 11/445 211/18722 0.0124053509949159 0.10796165723183 KLF4/STK3/HAX1/CPNE1/FERMT2/LRP2/HSP90AB1/PIK3CA/TCF7L2/GATA3/PDCD6 11 GO:1901653 cellular response to peptide 16/445 359/18722 0.0124138918385667 0.10796165723183 KLF4/CA2/AP3S1/VIM/RAP1B/GSTP1/SRSF5/RPL23/CHMP5/GRB2/KLF5/PIK3CA/PPARG/RAB8B/CSH1/ZNF106 16 GO:0050851 antigen receptor-mediated signaling pathway 12/445 240/18722 0.01257751047159 0.109154823021299 HLA-DRB1/PAWR/WNK1/HLA-A/HLA-DPB1/KHDRBS1/PIK3CA/PLCL2/GBP1/LAPTM5/GATA3/NFKBIZ 12 GO:0048144 fibroblast proliferation 6/445 81/18722 0.012645944349761 0.109518650123402 CD74/SFRP1/CTNNB1/MORC3/PAWR/GSTP1 6 GO:0001837 epithelial to mesenchymal transition 9/445 157/18722 0.0128967535942827 0.11083143181995 SFRP1/CTNNB1/FERMT2/HNRNPAB/WWTR1/RGCC/TCF7L2/GATA3/PDCD6 9 GO:0035455 response to interferon-alpha 3/445 21/18722 0.0129048459708051 0.11083143181995 EIF2AK2/IFNAR1/GATA3 3 GO:0045655 regulation of monocyte differentiation 3/445 21/18722 0.0129048459708051 0.11083143181995 CD74/HLA-DRB1/JUN 3 GO:0048485 sympathetic nervous system development 3/445 21/18722 0.0129048459708051 0.11083143181995 CTNNB1/SOX4/GATA3 3 GO:0019827 stem cell population maintenance 8/445 131/18722 0.0130843572663438 0.111676611296005 KLF4/GNL3/WNT7A/SFRP1/CTNNB1/SOX4/RTF1/LBH 8 GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 8/445 131/18722 0.0130843572663438 0.111676611296005 SKIL/SFRP1/FBN2/UBE2D1/PMEPA1/LRP2/PEG10/PPARG 8 GO:1904950 negative regulation of establishment of protein localization 8/445 131/18722 0.0130843572663438 0.111676611296005 APOE/SFRP1/ANXA1/GOPC/SP100/UBE2J1/RAB11FIP1/DNAJA1 8 GO:0046822 regulation of nucleocytoplasmic transport 7/445 106/18722 0.0132956156425238 0.112782875917975 NUTF2/IWS1/NUP58/SP100/HSP90AB1/KHDRBS1/TCF7L2 7 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors 6/445 82/18722 0.0133792595632624 0.112782875917975 SKIL/STK3/SFRP1/GABARAP/HMOX1/SP100 6 GO:0043242 negative regulation of protein-containing complex disassembly 6/445 82/18722 0.0133792595632624 0.112782875917975 LIMA1/TMOD3/GSN/CAPZA2/PIK3CA/RDX 6 GO:0060395 SMAD protein signal transduction 6/445 82/18722 0.0133792595632624 0.112782875917975 FOS/VIM/INHA/JUN/PPARG/WWTR1 6 GO:0001914 regulation of T cell mediated cytotoxicity 4/445 39/18722 0.0134323831884879 0.112782875917975 HLA-B/HLA-DRA/HLA-DRB1/HLA-A 4 GO:0045622 regulation of T-helper cell differentiation 4/445 39/18722 0.0134323831884879 0.112782875917975 HLA-DRA/HLA-DRB1/ANXA1/NFKBIZ 4 GO:0051084 'de novo' posttranslational protein folding 4/445 39/18722 0.0134323831884879 0.112782875917975 CD74/ERO1A/HSPA2/HSPA1B 4 GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation 4/445 39/18722 0.0134323831884879 0.112782875917975 HLA-DRA/HLA-DRB1/ANXA1/NFKBIZ 4 GO:0002237 response to molecule of bacterial origin 16/445 363/18722 0.013664971719038 0.114158865297109 FOS/JUND/CEBPB/VIM/S100A9/S100A8/LITAF/GSTP1/JUN/IFNAR1/SASH1/CHMP5/AKAP12/HPGD/RHOA/SPARC 16 GO:0000082 G1/S transition of mitotic cell cycle 11/445 214/18722 0.0136653232525834 0.114158865297109 KLF4/ANXA1/ADAMTS1/SOX4/PLK2/AIF1/KHDRBS1/BRD7/RDX/RGCC/WEE1 11 GO:0072001 renal system development 14/445 302/18722 0.0136791668656667 0.114158865297109 OSR2/CA2/SFRP1/CTNNB1/ADAMTS1/SOX4/BASP1/LRP2/IRX2/SERPINF1/HPGD/WWTR1/RHOA/GATA3 14 GO:1902115 regulation of organelle assembly 10/445 186/18722 0.0137196529768351 0.114265900095375 CCSAP/CENPJ/GSN/ODF2L/CHMP5/HSPA1B/PLK2/MAP4/RDX/RHOA 10 GO:0031532 actin cytoskeleton reorganization 7/445 107/18722 0.01394521623024 0.115910841543504 ANXA1/HAX1/GSN/GRB2/TJP1/CLDN19/RHOA 7 GO:0007162 negative regulation of cell adhesion 14/445 303/18722 0.014042369291218 0.116483991048236 KLF4/CD74/MYADM/CEBPB/HLA-DRB1/ANXA1/PAWR/WNK1/IRF1/RDX/GBP1/RGCC/RHOA/LAPTM5 14 GO:0031669 cellular response to nutrient levels 11/445 215/18722 0.0141061258564316 0.116778368562964 SFRP1/GABARAP/PIM1/HMOX1/EIF2AK2/JUN/TRIM24/EIF2AK4/CBL/HNRNPA1/ATF4 11 GO:0043001 Golgi to plasma membrane protein transport 4/445 40/18722 0.0146516018870509 0.119877042088261 GOPC/GOLGA4/MACF1/GOLPH3 4 GO:0045429 positive regulation of nitric oxide biosynthetic process 4/445 40/18722 0.0146516018870509 0.119877042088261 KLF4/HSP90AB1/AIF1/HBB 4 GO:0045777 positive regulation of blood pressure 4/445 40/18722 0.0146516018870509 0.119877042088261 TPM1/TAC3/WNK1/RHOA 4 GO:0071276 cellular response to cadmium ion 4/445 40/18722 0.0146516018870509 0.119877042088261 FOS/HMOX1/JUN/MT2A 4 GO:0050860 negative regulation of T cell receptor signaling pathway 3/445 22/18722 0.0146835592584508 0.119877042088261 PAWR/GBP1/LAPTM5 3 GO:0051220 cytoplasmic sequestering of protein 3/445 22/18722 0.0146835592584508 0.119877042088261 TMSB4X/SRI/GOPC 3 GO:0140467 integrated stress response signaling 3/445 22/18722 0.0146835592584508 0.119877042088261 PPP1R15A/EIF2AK4/ATF4 3 GO:0002366 leukocyte activation involved in immune response 13/445 275/18722 0.0148003618905572 0.119956122800477 CD74/HLA-DRA/HLA-DRB1/TYROBP/ANXA1/HMOX1/FCER1G/EIF2AK4/CBL/PLCL2/GATA3/VAMP8/NFKBIZ 13 GO:0098727 maintenance of cell number 8/445 134/18722 0.0148330897789143 0.119956122800477 KLF4/GNL3/WNT7A/SFRP1/CTNNB1/SOX4/RTF1/LBH 8 GO:0034113 heterotypic cell-cell adhesion 5/445 61/18722 0.0148384359116542 0.119956122800477 KLF4/MYADM/PKP2/WNK1/DSP 5 GO:0043954 cellular component maintenance 5/445 61/18722 0.0148384359116542 0.119956122800477 APOE/ZMYND8/FERMT2/CTBP2/TJP1 5 GO:0060998 regulation of dendritic spine development 5/445 61/18722 0.0148384359116542 0.119956122800477 APOE/TANC2/ZMYND8/MAPK6/PLK2 5 GO:0032370 positive regulation of lipid transport 6/445 84/18722 0.0149341110404029 0.120493774820126 APOE/SPP1/RXRA/TMF1/PPARG/DBI 6 GO:0034250 positive regulation of cellular amide metabolic process 9/445 162/18722 0.0155533820224128 0.125001986643166 PPP1R15A/VIM/SOX4/EIF2AK4/EIF4A3/KHDRBS1/RBM3/DNAJC3/RHOA 9 GO:0051100 negative regulation of binding 9/445 162/18722 0.0155533820224128 0.125001986643166 TMSB4X/SRI/HMOX1/JUN/CPNE1/SP100/GOLGA2/EIF4A3/RSF1 9 GO:0001656 metanephros development 6/445 85/18722 0.0157567245652653 0.12590141040447 OSR2/CTNNB1/BASP1/IRX2/WWTR1/GATA3 6 GO:0032092 positive regulation of protein binding 6/445 85/18722 0.0157567245652653 0.12590141040447 APOE/STK3/HSP90AB1/PLK2/PLCL2/TCF7L2 6 GO:0071277 cellular response to calcium ion 6/445 85/18722 0.0157567245652653 0.12590141040447 FOS/JUND/SLC25A24/FOSB/CPNE1/WNK1 6 GO:0045576 mast cell activation 5/445 62/18722 0.0158344125207377 0.126134483688893 HMOX1/NDRG1/CBL/PLSCR1/VAMP8 5 GO:0051693 actin filament capping 4/445 41/18722 0.015938562209054 0.126134483688893 TMOD3/GSN/CAPZA2/RDX 4 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading 4/445 41/18722 0.015938562209054 0.126134483688893 MYADM/FERMT2/LIMS1/CALR 4 GO:1904407 positive regulation of nitric oxide metabolic process 4/445 41/18722 0.015938562209054 0.126134483688893 KLF4/HSP90AB1/AIF1/HBB 4 GO:2000008 regulation of protein localization to cell surface 4/445 41/18722 0.015938562209054 0.126134483688893 CTNNB1/TYROBP/GOPC/HSP90AB1 4 GO:0009408 response to heat 7/445 110/18722 0.016029954231838 0.126435464862295 HMOX1/HSPA2/IER5/HSP90AB1/HSPA1B/PDCD6/DNAJA1 7 GO:0003158 endothelium development 8/445 136/18722 0.0160894664873931 0.126435464862295 MYADM/CTNNB1/RAP1B/RHOB/VEZF1/TJP1/RDX/RHOA 8 GO:0050657 nucleic acid transport 9/445 163/18722 0.016129627204655 0.126435464862295 NUTF2/IWS1/NUP58/SMG1/YBX1/EIF4A3/YTHDC1/HNRNPA1/KHDRBS1 9 GO:0050658 RNA transport 9/445 163/18722 0.016129627204655 0.126435464862295 NUTF2/IWS1/NUP58/SMG1/YBX1/EIF4A3/YTHDC1/HNRNPA1/KHDRBS1 9 GO:0072331 signal transduction by p53 class mediator 9/445 163/18722 0.016129627204655 0.126435464862295 CD74/ING2/TRIM24/RPS15/RPL23/SP100/NDRG1/SOX4/PLK2 9 GO:0046883 regulation of hormone secretion 12/445 249/18722 0.0163776443078398 0.128136455749406 SFRP1/HLA-DRB1/SPP1/SRI/ANXA1/INHA/SOX4/TMF1/RAB8B/TCF7L2/VAMP8/RAB11FIP1 12 GO:0001654 eye development 16/445 371/18722 0.0164609467309785 0.128369643946962 OSR2/LPCAT1/KLF4/SKIL/WNT7A/FBN2/CTNNB1/VIM/THRB/HMGN1/GNB1/EFEMP1/BIRC7/SERPINF1/ATF4/GATA3 16 GO:0002263 cell activation involved in immune response 13/445 279/18722 0.0164878253091706 0.128369643946962 CD74/HLA-DRA/HLA-DRB1/TYROBP/ANXA1/HMOX1/FCER1G/EIF2AK4/CBL/PLCL2/GATA3/VAMP8/NFKBIZ 13 GO:0035162 embryonic hemopoiesis 3/445 23/18722 0.0165938973293822 0.128369643946962 STK3/ATF4/GATA3 3 GO:0045943 positive regulation of transcription by RNA polymerase I 3/445 23/18722 0.0165938973293822 0.128369643946962 NCL/SMARCB1/ATF4 3 GO:0051457 maintenance of protein location in nucleus 3/445 23/18722 0.0165938973293822 0.128369643946962 MORC3/TAF3/SP100 3 GO:0071305 cellular response to vitamin D 3/445 23/18722 0.0165938973293822 0.128369643946962 SFRP1/PIM1/TRIM24 3 GO:0045471 response to ethanol 8/445 137/18722 0.0167456938294642 0.129301796653302 S100A8/GSTP1/CBL/HPGD/GGH/RHOA/SPARC/GATA3 8 GO:0030239 myofibril assembly 5/445 63/18722 0.016873972539111 0.129807040147239 KRT19/TPM1/KRT8/CSRP1/TMOD3 5 GO:0031343 positive regulation of cell killing 5/445 63/18722 0.016873972539111 0.129807040147239 HLA-B/HLA-DRA/HLA-DRB1/TYROBP/HLA-A 5 GO:0032689 negative regulation of interferon-gamma production 4/445 42/18722 0.0172943450438605 0.132301739585533 HLA-DRB1/INHA/LAPTM5/GATA3 4 GO:0035019 somatic stem cell population maintenance 4/445 42/18722 0.0172943450438605 0.132301739585533 WNT7A/SFRP1/SOX4/LBH 4 GO:0045214 sarcomere organization 4/445 42/18722 0.0172943450438605 0.132301739585533 KRT19/TPM1/KRT8/CSRP1 4 GO:0055076 transition metal ion homeostasis 8/445 138/18722 0.0174209953717067 0.133024273346618 FTL/S100A9/SRI/SLC25A37/HMOX1/S100A8/MT2A/SLC40A1 8 GO:0002821 positive regulation of adaptive immune response 7/445 112/18722 0.0175368886053834 0.13317074784713 HLA-B/HLA-DRA/HLA-DRB1/EIF2AK4/HLA-A/GATA3/NFKBIZ 7 GO:0010633 negative regulation of epithelial cell migration 7/445 112/18722 0.0175368886053834 0.13317074784713 APOE/KLF4/SP100/SERPINF1/PPARG/RGCC/RHOA 7 GO:0046632 alpha-beta T cell differentiation 7/445 112/18722 0.0175368886053834 0.13317074784713 HLA-DRA/HLA-DRB1/ANXA1/IRF1/RHOA/GATA3/NFKBIZ 7 GO:0050777 negative regulation of immune response 10/445 194/18722 0.0179120573813146 0.135125350524495 HLA-B/HLA-DRB1/ANXA1/HMOX1/RIOK3/HLA-A/PARP14/RPS19/PLK2/PPARG 10 GO:0051236 establishment of RNA localization 9/445 166/18722 0.0179522948074653 0.135125350524495 NUTF2/IWS1/NUP58/SMG1/YBX1/EIF4A3/YTHDC1/HNRNPA1/KHDRBS1 9 GO:0001885 endothelial cell development 5/445 64/18722 0.0179578352548893 0.135125350524495 MYADM/RAP1B/VEZF1/TJP1/RDX 5 GO:0055002 striated muscle cell development 5/445 64/18722 0.0179578352548893 0.135125350524495 KRT19/TPM1/KRT8/CSRP1/TMOD3 5 GO:1903018 regulation of glycoprotein metabolic process 5/445 64/18722 0.0179578352548893 0.135125350524495 CTNNB1/PAWR/GOLGA2/CST3/TCF7L2 5 GO:0002274 myeloid leukocyte activation 11/445 223/18722 0.0180291461695629 0.135415277866298 JUND/CD74/TYROBP/HMOX1/NDRG1/FCER1G/CBL/C1QA/AIF1/PLSCR1/VAMP8 11 GO:2001234 negative regulation of apoptotic signaling pathway 11/445 224/18722 0.0185713704411415 0.139234721038758 CD74/CTNNB1/ING2/HMOX1/GSTP1/RB1CC1/HSPA1B/MCL1/CTNNA1/TCF7L2/DNAJA1 11 GO:2000679 positive regulation of transcription regulatory region DNA binding 3/445 24/18722 0.0186367159412838 0.139471510060586 KLF4/CTNNB1/GATA3 3 GO:0006458 'de novo' protein folding 4/445 43/18722 0.018719949243072 0.139588646792655 CD74/ERO1A/HSPA2/HSPA1B 4 GO:0014002 astrocyte development 4/445 43/18722 0.018719949243072 0.139588646792655 VIM/S100A9/S100A8/C1QA 4 GO:0002696 positive regulation of leukocyte activation 17/445 409/18722 0.0189368390838504 0.140951499559254 JUND/CD74/HLA-DRA/HLA-DRB1/TYROBP/ANXA1/SLC7A1/SOX4/HLA-DPA1/HLA-A/HLA-DPB1/AIF1/PIK3CA/RHOA/GATA3/VAMP8/NFKBIZ 17 GO:0002720 positive regulation of cytokine production involved in immune response 5/445 65/18722 0.0190866914213123 0.141705019861286 CD74/HLA-A/SLC7A5/LAPTM5/GATA3 5 GO:0010001 glial cell differentiation 11/445 225/18722 0.0191256161616091 0.141705019861286 CTNNB1/VIM/SPINT1/S100A9/BNIP3/S100A8/GSTP1/NDRG1/SOX4/C1QA/RHOA 11 GO:0046660 female sex differentiation 7/445 114/18722 0.0191409830749449 0.141705019861286 CEBPB/SFRP1/INHA/ADAMTS1/LRP2/CTNNA1/NRIP1 7 GO:1903362 regulation of cellular protein catabolic process 12/445 255/18722 0.0193548556142431 0.142563550326677 APOE/GABARAP/RYBP/RPL23/TMF1/LRP2/UBE2V2/HSP90AB1/HSPA1B/PLK2/RDX/LAPTM5 12 GO:0014910 regulation of smooth muscle cell migration 6/445 89/18722 0.0193604821431289 0.142563550326677 IGFBP3/TPM1/GSTP1/ADAMTS1/AIF1/RHOA 6 GO:1900407 regulation of cellular response to oxidative stress 6/445 89/18722 0.0193604821431289 0.142563550326677 PAGE4/CTNNB1/PAWR/MAPKAP1/MCL1/ATF4 6 GO:0019058 viral life cycle 14/445 317/18722 0.0199474044444357 0.14634555411878 APOE/CD74/HLA-DRB1/SMARCB1/EIF2AK2/GSN/CTBP2/EIF2AK4/CHMP5/MX1/HSP90AB1/HSPA1B/PLSCR1/VAMP8 14 GO:0046916 cellular transition metal ion homeostasis 7/445 115/18722 0.0199803661396737 0.14634555411878 FTL/S100A9/SRI/HMOX1/S100A8/MT2A/SLC40A1 7 GO:1901989 positive regulation of cell cycle phase transition 7/445 115/18722 0.0199803661396737 0.14634555411878 ANXA1/HSPA2/TMOD3/ADAMTS1/AIF1/RDX/RGCC 7 GO:0042093 T-helper cell differentiation 5/445 66/18722 0.020261202663471 0.147617333691003 HLA-DRA/HLA-DRB1/ANXA1/GATA3/NFKBIZ 5 GO:0051893 regulation of focal adhesion assembly 5/445 66/18722 0.020261202663471 0.147617333691003 SFRP1/FERMT2/LIMS1/MACF1/RHOA 5 GO:0090109 regulation of cell-substrate junction assembly 5/445 66/18722 0.020261202663471 0.147617333691003 SFRP1/FERMT2/LIMS1/MACF1/RHOA 5 GO:0030901 midbrain development 6/445 90/18722 0.0203422110350864 0.147946608778067 SFRP1/CTNNB1/MAPKAP1/BASP1/UQCRQ/RHOA 6 GO:0030099 myeloid cell differentiation 16/445 381/18722 0.0205551044747908 0.149232225984817 FOS/CA2/CD74/CEBPB/SFRP1/CTNNB1/HLA-DRB1/TYROBP/HAX1/INHA/TMOD3/JUN/RPS19/HSPA1B/PPARG/GATA3 16 GO:0015012 heparan sulfate proteoglycan biosynthetic process 3/445 25/18722 0.0208125653707148 0.149239408880718 CTNNB1/HS6ST1/TCF7L2 3 GO:0033119 negative regulation of RNA splicing 3/445 25/18722 0.0208125653707148 0.149239408880718 SFSWAP/SRSF4/SRSF9 3 GO:0045109 intermediate filament organization 3/445 25/18722 0.0208125653707148 0.149239408880718 VIM/PKP2/DSP 3 GO:0060706 cell differentiation involved in embryonic placenta development 3/445 25/18722 0.0208125653707148 0.149239408880718 KRT19/STK3/KRT8 3 GO:0090169 regulation of spindle assembly 3/445 25/18722 0.0208125653707148 0.149239408880718 CCSAP/CHMP5/HSPA1B 3 GO:0098581 detection of external biotic stimulus 3/445 25/18722 0.0208125653707148 0.149239408880718 HLA-B/HLA-DRB1/HLA-A 3 GO:0097193 intrinsic apoptotic signaling pathway 13/445 288/18722 0.0208159688113004 0.149239408880718 CD74/SKIL/CEBPB/PPP1R15A/ING2/S100A9/ERO1A/BNIP3/HMOX1/S100A8/MCL1/ATF4/DNAJA1 13 GO:0021782 glial cell development 7/445 116/18722 0.0208451074616738 0.149239408880718 VIM/S100A9/S100A8/GSTP1/NDRG1/SOX4/C1QA 7 GO:0071356 cellular response to tumor necrosis factor 11/445 229/18722 0.0214657642288476 0.153267954916868 TMSB4X/KRT8/SFRP1/GSTP1/CPNE1/LIMS1/HSPA1B/AKAP12/GBP1/LAPTM5/GATA3 11 GO:2000514 regulation of CD4-positive, alpha-beta T cell activation 5/445 67/18722 0.0214820009433228 0.153267954916868 HLA-DRA/HLA-DRB1/ANXA1/GATA3/NFKBIZ 5 GO:0051225 spindle assembly 7/445 117/18722 0.0217355494301586 0.153415285573852 CCSAP/KIF2A/GOLGA2/CHMP5/HSPA1B/LSM14A/RHOA 7 GO:0031670 cellular response to nutrient 4/445 45/18722 0.0217842080398268 0.153415285573852 SFRP1/PIM1/HMOX1/TRIM24 4 GO:0035307 positive regulation of protein dephosphorylation 4/445 45/18722 0.0217842080398268 0.153415285573852 ANKLE2/PPP1R15A/HSP90AB1/CAMTA1 4 GO:1901985 positive regulation of protein acetylation 4/445 45/18722 0.0217842080398268 0.153415285573852 SMARCB1/SOX4/BRD7/GATA3 4 GO:0034504 protein localization to nucleus 13/445 290/18722 0.0218836304977129 0.153415285573852 NUTF2/MORC3/NUP58/RPL23/TAF3/SP100/FERMT2/HSP90AB1/TXNIP/CALR/WWTR1/CTNNA1/CCT6A 13 GO:0044403 biological process involved in symbiotic interaction 13/445 290/18722 0.0218836304977129 0.153415285573852 APOE/CD74/HLA-DRB1/SMARCB1/JUN/GSN/RXRA/EIF2AK4/HSP90AB1/CBL/HSPA1B/PLSCR1/VAMP8 13 GO:1990138 neuron projection extension 9/445 172/18722 0.0220402349456238 0.153415285573852 APOE/CTNNB1/SEMA4C/CPNE1/SHTN1/GOLGA4/EIF2AK4/HSP90AB1/MACF1 9 GO:0030595 leukocyte chemotaxis 11/445 230/18722 0.0220823226352129 0.153415285573852 CD74/S100A9/ANXA1/S100A8/SBDS/FCER1G/MTUS1/WNK1/RPS19/AIF1/CALR 11 GO:0051091 positive regulation of DNA-binding transcription factor activity 12/445 260/18722 0.0221302691365756 0.153415285573852 STK3/ARHGEF5/CTNNB1/S100A9/UBE2V1/S100A8/SMARCB1/EIF2AK2/HSPA1B/PLPP3/PPARG/RGCC 12 GO:0003330 regulation of extracellular matrix constituent secretion 2/445 10/18722 0.0223568147943498 0.153415285573852 IER3IP1/RGCC 2 GO:0009950 dorsal/ventral axis specification 2/445 10/18722 0.0223568147943498 0.153415285573852 SFRP1/CTNNB1 2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline 2/445 10/18722 0.0223568147943498 0.153415285573852 P4HA1/ERO1A 2 GO:0032025 response to cobalt ion 2/445 10/18722 0.0223568147943498 0.153415285573852 BNIP3/SERPINF1 2 GO:0032275 luteinizing hormone secretion 2/445 10/18722 0.0223568147943498 0.153415285573852 CGA/TMF1 2 GO:0042989 sequestering of actin monomers 2/445 10/18722 0.0223568147943498 0.153415285573852 TMSB4X/GSN 2 GO:0045792 negative regulation of cell size 2/445 10/18722 0.0223568147943498 0.153415285573852 RDX/RHOA 2 GO:0048194 Golgi vesicle budding 2/445 10/18722 0.0223568147943498 0.153415285573852 ARFGAP3/GOLPH3 2 GO:0048262 determination of dorsal/ventral asymmetry 2/445 10/18722 0.0223568147943498 0.153415285573852 CTNNB1/AIDA 2 GO:0060272 embryonic skeletal joint morphogenesis 2/445 10/18722 0.0223568147943498 0.153415285573852 OSR2/CTNNB1 2 GO:0060768 regulation of epithelial cell proliferation involved in prostate gland development 2/445 10/18722 0.0223568147943498 0.153415285573852 CTNNB1/SERPINF1 2 GO:0070561 vitamin D receptor signaling pathway 2/445 10/18722 0.0223568147943498 0.153415285573852 PIM1/TRIM24 2 GO:0150172 regulation of phosphatidylcholine metabolic process 2/445 10/18722 0.0223568147943498 0.153415285573852 APOC1/LPCAT1 2 GO:1901838 positive regulation of transcription of nucleolar large rRNA by RNA polymerase I 2/445 10/18722 0.0223568147943498 0.153415285573852 NCL/SMARCB1 2 GO:0031058 positive regulation of histone modification 6/445 92/18722 0.0224058871453729 0.153497047757107 CTNNB1/ING2/SMARCB1/RTF1/BRD7/GATA3 6 GO:0036293 response to decreased oxygen levels 14/445 322/18722 0.02245720843916 0.153593920632732 SFRP1/LDHA/ERO1A/BNIP3/HMOX1/BNIP3L/NDRG1/GNB1/CBL/ANGPTL4/HILPDA/PLOD2/RGCC/RHOA 14 GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response 5/445 68/18722 0.0227496880817321 0.155080794497748 HLA-DRA/HLA-DRB1/ANXA1/GATA3/NFKBIZ 5 GO:0046686 response to cadmium ion 5/445 68/18722 0.0227496880817321 0.155080794497748 FOS/HMOX1/JUN/MT2A/SPARC 5 GO:0050727 regulation of inflammatory response 16/445 386/18722 0.0228728637901352 0.155663591955599 APOE/KLF4/TMSB4X/CEBPB/HLA-DRB1/S100A9/ANXA1/S100A8/GSTP1/RPS19/PLK2/SERPINF1/PPARG/GATA3/VAMP8/NFKBIZ 16 GO:0010875 positive regulation of cholesterol efflux 3/445 26/18722 0.0231217088588739 0.156071534797399 APOE/RXRA/PPARG 3 GO:0034114 regulation of heterotypic cell-cell adhesion 3/445 26/18722 0.0231217088588739 0.156071534797399 KLF4/MYADM/WNK1 3 GO:0045672 positive regulation of osteoclast differentiation 3/445 26/18722 0.0231217088588739 0.156071534797399 FOS/CA2/TYROBP 3 GO:0051016 barbed-end actin filament capping 3/445 26/18722 0.0231217088588739 0.156071534797399 GSN/CAPZA2/RDX 3 GO:0097066 response to thyroid hormone 3/445 26/18722 0.0231217088588739 0.156071534797399 THRB/CTSS/RDX 3 GO:0009636 response to toxic substance 12/445 262/18722 0.0233191352962875 0.156891446105804 FOS/APOE/HBA2/S100A9/HBA1/PIM1/HBG2/GSTP1/MT2A/SRSF9/PON2/HBB 12 GO:0031330 negative regulation of cellular catabolic process 12/445 262/18722 0.0233191352962875 0.156891446105804 APOC1/RYBP/HMOX1/PKP3/RPL23/GOLGA2/SMG1/YBX1/HSP90AB1/MCL1/CST3/PIK3CA 12 GO:0055010 ventricular cardiac muscle tissue morphogenesis 4/445 46/18722 0.0234244524046654 0.157088332603365 TPM1/PKP2/LRP2/DSP 4 GO:0061028 establishment of endothelial barrier 4/445 46/18722 0.0234244524046654 0.157088332603365 MYADM/RAP1B/TJP1/RDX 4 GO:0060993 kidney morphogenesis 6/445 93/18722 0.0234887152425874 0.157263991356773 CTNNB1/SOX4/BASP1/IRX2/WWTR1/GATA3 6 GO:0032102 negative regulation of response to external stimulus 17/445 420/18722 0.0237442430590325 0.15820559367236 APOE/KLF4/HLA-B/HLA-DRB1/SPP1/SEMA4C/GSTP1/RIOK3/HLA-A/PARP14/RPS19/PLK2/AIF1/SERPINF1/PPARG/CLDN19/GATA3 17 GO:0034329 cell junction assembly 17/445 420/18722 0.0237442430590325 0.15820559367236 WNT7A/SFRP1/CTNNB1/RAP1B/PKP3/FERMT2/PKP2/CLDN7/PAK2/UBE2V2/LIMS1/COL17A1/TJP1/MACF1/CLDN19/CTNNA1/RHOA 17 GO:0050867 positive regulation of cell activation 17/445 420/18722 0.0237442430590325 0.15820559367236 JUND/CD74/HLA-DRA/HLA-DRB1/TYROBP/ANXA1/SLC7A1/SOX4/HLA-DPA1/HLA-A/HLA-DPB1/AIF1/PIK3CA/RHOA/GATA3/VAMP8/NFKBIZ 17 GO:0002287 alpha-beta T cell activation involved in immune response 5/445 69/18722 0.0240648353362176 0.15931383777871 HLA-DRA/HLA-DRB1/ANXA1/GATA3/NFKBIZ 5 GO:0002293 alpha-beta T cell differentiation involved in immune response 5/445 69/18722 0.0240648353362176 0.15931383777871 HLA-DRA/HLA-DRB1/ANXA1/GATA3/NFKBIZ 5 GO:0031060 regulation of histone methylation 5/445 69/18722 0.0240648353362176 0.15931383777871 CTNNB1/IWS1/SMARCB1/RTF1/GATA3 5 GO:0034605 cellular response to heat 5/445 69/18722 0.0240648353362176 0.15931383777871 HMOX1/IER5/HSP90AB1/HSPA1B/PDCD6 5 GO:1901888 regulation of cell junction assembly 10/445 204/18722 0.0243954733929059 0.161033362520255 WNT7A/SFRP1/RAP1B/FERMT2/UBE2V2/LIMS1/TJP1/MACF1/CLDN19/RHOA 10 GO:1903531 negative regulation of secretion by cell 8/445 147/18722 0.0244025381112757 0.161033362520255 APOE/SFRP1/RAP1B/ANXA1/INHA/HMOX1/VAMP8/RAB11FIP1 8 GO:0019080 viral gene expression 6/445 94/18722 0.0246061005309301 0.161602227811243 SMARCB1/JUN/GALNT1/EIF2AK4/DENR/RSF1 6 GO:0030316 osteoclast differentiation 6/445 94/18722 0.0246061005309301 0.161602227811243 FOS/CA2/CEBPB/SFRP1/CTNNB1/TYROBP 6 GO:1902414 protein localization to cell junction 6/445 94/18722 0.0246061005309301 0.161602227811243 WNT7A/FERMT2/PAK2/TJP1/JAK1/DSP 6 GO:0060560 developmental growth involved in morphogenesis 11/445 234/18722 0.0246789483495022 0.161823389891736 APOE/SFRP1/CTNNB1/SPP1/SEMA4C/CPNE1/SHTN1/GOLGA4/EIF2AK4/HSP90AB1/MACF1 11 GO:0043534 blood vessel endothelial cell migration 9/445 176/18722 0.0251119295512289 0.162846672845797 APOE/KLF4/TMSB4X/ANXA1/HMOX1/PLK2/PPARG/RGCC/RHOA 9 GO:0050728 negative regulation of inflammatory response 9/445 176/18722 0.0251119295512289 0.162846672845797 APOE/KLF4/HLA-DRB1/GSTP1/RPS19/PLK2/SERPINF1/PPARG/GATA3 9 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 4/445 47/18722 0.0251376988242342 0.162846672845797 GSTP1/CPNE1/HSPA1B/LAPTM5 4 GO:0035850 epithelial cell differentiation involved in kidney development 4/445 47/18722 0.0251376988242342 0.162846672845797 CTNNB1/BASP1/WWTR1/GATA3 4 GO:0043114 regulation of vascular permeability 4/445 47/18722 0.0251376988242342 0.162846672845797 APOE/FERMT2/AKAP12/TJP1 4 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 4/445 47/18722 0.0251376988242342 0.162846672845797 CEBPB/HMOX1/JUN/ATF4 4 GO:0048483 autonomic nervous system development 4/445 47/18722 0.0251376988242342 0.162846672845797 CTNNB1/SOX4/NAV2/GATA3 4 GO:0051607 defense response to virus 12/445 265/18722 0.0251897903530536 0.162846672845797 BNIP3/EIF2AK2/RIOK3/BNIP3L/EIF2AK4/IRF1/MX1/PLSCR1/LSM14A/DNAJC3/GBP1/VAMP8 12 GO:0140546 defense response to symbiont 12/445 265/18722 0.0251897903530536 0.162846672845797 BNIP3/EIF2AK2/RIOK3/BNIP3L/EIF2AK4/IRF1/MX1/PLSCR1/LSM14A/DNAJC3/GBP1/VAMP8 12 GO:0051384 response to glucocorticoid 8/445 148/18722 0.0252835425615674 0.162971394109811 FOS/ANXA1/GSTP1/FOSB/AIF1/SERPINF1/RHOA/SPARC 8 GO:0048193 Golgi vesicle transport 13/445 296/18722 0.0253319905015773 0.162971394109811 AP3S1/GOPC/GOLGA2/SNX2/GOLGA4/ARFGAP3/PLPP3/MACF1/IER3IP1/RAB8B/LAPTM5/GOLPH3/PDCD6 13 GO:0045931 positive regulation of mitotic cell cycle 7/445 121/18722 0.0255609216901762 0.162971394109811 ANXA1/HSPA2/TMOD3/ADAMTS1/AIF1/RDX/RGCC 7 GO:0018126 protein hydroxylation 3/445 27/18722 0.0255641402525193 0.162971394109811 P4HA1/ERO1A/PLOD2 3 GO:0032703 negative regulation of interleukin-2 production 3/445 27/18722 0.0255641402525193 0.162971394109811 GBP1/LAPTM5/GATA3 3 GO:0033688 regulation of osteoblast proliferation 3/445 27/18722 0.0255641402525193 0.162971394109811 SFRP1/EIF2AK2/RHOA 3 GO:0035116 embryonic hindlimb morphogenesis 3/445 27/18722 0.0255641402525193 0.162971394109811 OSR2/WNT7A/CTNNB1 3 GO:1902914 regulation of protein polyubiquitination 3/445 27/18722 0.0255641402525193 0.162971394109811 GABARAP/UBE2D1/SASH1 3 GO:1903203 regulation of oxidative stress-induced neuron death 3/445 27/18722 0.0255641402525193 0.162971394109811 CTNNB1/MCL1/ATF4 3 GO:0007044 cell-substrate junction assembly 6/445 95/18722 0.0257584478339561 0.162978819899718 SFRP1/FERMT2/LIMS1/COL17A1/MACF1/RHOA 6 GO:0008585 female gonad development 6/445 95/18722 0.0257584478339561 0.162978819899718 CEBPB/SFRP1/INHA/ADAMTS1/CTNNA1/NRIP1 6 GO:1903321 negative regulation of protein modification by small protein conjugation or removal 6/445 95/18722 0.0257584478339561 0.162978819899718 CTNNB1/RPS15/RPL23/SOX4/HSPA1B/DNAJA1 6 GO:0010720 positive regulation of cell development 13/445 298/18722 0.0265659992256226 0.162978819899718 MYADM/SKIL/CTNNB1/SPINT1/TYROBP/FERMT2/SHTN1/GOLGA4/LRP2/LIMS1/SERPINF1/MACF1/CALR 13 GO:0050868 negative regulation of T cell activation 7/445 122/18722 0.026584749711353 0.162978819899718 CD74/CEBPB/HLA-DRB1/ANXA1/PAWR/IRF1/LAPTM5 7 GO:0003281 ventricular septum development 5/445 71/18722 0.0268396402521941 0.162978819899718 LUZP1/SOX4/LRP2/LMO4/GATA3 5 GO:0045824 negative regulation of innate immune response 5/445 71/18722 0.0268396402521941 0.162978819899718 HLA-B/HLA-A/PARP14/RPS19/PPARG 5 GO:0150116 regulation of cell-substrate junction organization 5/445 71/18722 0.0268396402521941 0.162978819899718 SFRP1/FERMT2/LIMS1/MACF1/RHOA 5 GO:0001731 formation of translation preinitiation complex 2/445 11/18722 0.0269007596726893 0.162978819899718 EIF4H/DENR 2 GO:0002357 defense response to tumor cell 2/445 11/18722 0.0269007596726893 0.162978819899718 KLF4/LAPTM5 2 GO:0003263 cardioblast proliferation 2/445 11/18722 0.0269007596726893 0.162978819899718 CTNNB1/PIM1 2 GO:0003264 regulation of cardioblast proliferation 2/445 11/18722 0.0269007596726893 0.162978819899718 CTNNB1/PIM1 2 GO:0006020 inositol metabolic process 2/445 11/18722 0.0269007596726893 0.162978819899718 IMPA2/ISYNA1 2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c 2/445 11/18722 0.0269007596726893 0.162978819899718 UQCR10/UQCRQ 2 GO:0033625 positive regulation of integrin activation 2/445 11/18722 0.0269007596726893 0.162978819899718 RAP1B/FERMT2 2 GO:0035457 cellular response to interferon-alpha 2/445 11/18722 0.0269007596726893 0.162978819899718 IFNAR1/GATA3 2 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress 2/445 11/18722 0.0269007596726893 0.162978819899718 HMOX1/ATF4 2 GO:0045793 positive regulation of cell size 2/445 11/18722 0.0269007596726893 0.162978819899718 RB1CC1/HSP90AB1 2 GO:0046598 positive regulation of viral entry into host cell 2/445 11/18722 0.0269007596726893 0.162978819899718 CD74/HLA-DRB1 2 GO:0048102 autophagic cell death 2/445 11/18722 0.0269007596726893 0.162978819899718 BNIP3/LAPTM5 2 GO:0048103 somatic stem cell division 2/445 11/18722 0.0269007596726893 0.162978819899718 WNT7A/LBH 2 GO:0060742 epithelial cell differentiation involved in prostate gland development 2/445 11/18722 0.0269007596726893 0.162978819899718 CTNNB1/PSAP 2 GO:0060767 epithelial cell proliferation involved in prostate gland development 2/445 11/18722 0.0269007596726893 0.162978819899718 CTNNB1/SERPINF1 2 GO:0070417 cellular response to cold 2/445 11/18722 0.0269007596726893 0.162978819899718 EIF2AK4/DNAJC3 2 GO:0075294 positive regulation by symbiont of entry into host 2/445 11/18722 0.0269007596726893 0.162978819899718 CD74/HLA-DRB1 2 GO:0090084 negative regulation of inclusion body assembly 2/445 11/18722 0.0269007596726893 0.162978819899718 HSPA2/HSPA1B 2 GO:0090649 response to oxygen-glucose deprivation 2/445 11/18722 0.0269007596726893 0.162978819899718 BNIP3/CBL 2 GO:0098883 synapse pruning 2/445 11/18722 0.0269007596726893 0.162978819899718 C1QB/C1QA 2 GO:1902033 regulation of hematopoietic stem cell proliferation 2/445 11/18722 0.0269007596726893 0.162978819899718 PIM1/EIF2AK2 2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 2/445 11/18722 0.0269007596726893 0.162978819899718 CEBPB/ATF4 2 GO:2000615 regulation of histone H3-K9 acetylation 2/445 11/18722 0.0269007596726893 0.162978819899718 SMARCB1/GATA3 2 GO:2000644 regulation of receptor catabolic process 2/445 11/18722 0.0269007596726893 0.162978819899718 APOE/LAPTM5 2 GO:0002718 regulation of cytokine production involved in immune response 6/445 96/18722 0.0269461471778037 0.162978819899718 CD74/HMOX1/HLA-A/SLC7A5/LAPTM5/GATA3 6 GO:0034620 cellular response to unfolded protein 6/445 96/18722 0.0269461471778037 0.162978819899718 PPP1R15A/ERO1A/HSPA2/EIF2AK2/HSPA1B/ATF4 6 GO:1904035 regulation of epithelial cell apoptotic process 6/445 96/18722 0.0269461471778037 0.162978819899718 HMOX1/GSN/ANGPTL4/RGCC/TCF7L2/GATA3 6 GO:0051251 positive regulation of lymphocyte activation 15/445 362/18722 0.0270759365529933 0.163524406287157 CD74/HLA-DRA/HLA-DRB1/TYROBP/ANXA1/SLC7A1/SOX4/HLA-DPA1/HLA-A/HLA-DPB1/AIF1/PIK3CA/RHOA/GATA3/NFKBIZ 15 GO:0032103 positive regulation of response to external stimulus 17/445 427/18722 0.027252601252398 0.164351088720666 CD74/TMSB4X/CEBPB/TYROBP/S100A9/S100A8/RIOK3/PAK2/WNK1/SASH1/RPS19/AIF1/PLSCR1/LSM14A/CALR/VAMP8/NFKBIZ 17 GO:0010950 positive regulation of endopeptidase activity 9/445 179/18722 0.0276068543030272 0.165937573465635 NLRP2/S100A9/S100A8/GSN/CTSD/PPARG/RHOA/LAPTM5/PDCD6 9 GO:0010811 positive regulation of cell-substrate adhesion 7/445 123/18722 0.0276361778127226 0.165937573465635 PLEKHA2/MYADM/SFRP1/FERMT2/LIMS1/CCDC80/CALR 7 GO:0030168 platelet activation 7/445 123/18722 0.0276361778127226 0.165937573465635 APOE/VAV2/CSRP1/FCER1G/PLSCR1/PIK3CA/HBB 7 GO:0007141 male meiosis I 3/445 28/18722 0.0281396008701426 0.167436702431402 ING2/HSPA2/FOXJ3 3 GO:0031342 negative regulation of cell killing 3/445 28/18722 0.0281396008701426 0.167436702431402 HLA-B/HLA-A/HSP90AB1 3 GO:0045589 regulation of regulatory T cell differentiation 3/445 28/18722 0.0281396008701426 0.167436702431402 HLA-DRA/HLA-DRB1/IRF1 3 GO:0051894 positive regulation of focal adhesion assembly 3/445 28/18722 0.0281396008701426 0.167436702431402 SFRP1/FERMT2/LIMS1 3 GO:0061082 myeloid leukocyte cytokine production 3/445 28/18722 0.0281396008701426 0.167436702431402 CD74/HMOX1/LAPTM5 3 GO:1903672 positive regulation of sprouting angiogenesis 3/445 28/18722 0.0281396008701426 0.167436702431402 KLF4/TJP1/JAK1 3 GO:0014909 smooth muscle cell migration 6/445 97/18722 0.028169573514845 0.167436702431402 IGFBP3/TPM1/GSTP1/ADAMTS1/AIF1/RHOA 6 GO:0072593 reactive oxygen species metabolic process 11/445 239/18722 0.0282285772854818 0.167490652626852 PAGE4/RFK/HBA2/TYROBP/HBA1/HBG2/BNIP3/GSTP1/GRB2/HBB/RHOA 11 GO:0030330 DNA damage response, signal transduction by p53 class mediator 5/445 72/18722 0.0283002845639174 0.167490652626852 CD74/SP100/NDRG1/SOX4/PLK2 5 GO:0071479 cellular response to ionizing radiation 5/445 72/18722 0.0283002845639174 0.167490652626852 SFRP1/RHOB/NET1/GRB2/GATA3 5 GO:0043409 negative regulation of MAPK cascade 9/445 180/18722 0.0284759433889754 0.167945335063051 APOE/KLF4/SFRP1/AIDA/GSTP1/DUSP4/PPARG/GBP1/DNAJA1 9 GO:0042063 gliogenesis 13/445 301/18722 0.0284990752551921 0.167945335063051 CTNNB1/VIM/SPINT1/S100A9/ANXA1/BNIP3/S100A8/GSTP1/NDRG1/SOX4/LRP2/C1QA/RHOA 13 GO:0042886 amide transport 13/445 301/18722 0.0284990752551921 0.167945335063051 CA2/CD74/SFRP1/HLA-DRB1/SRI/ANXA1/S100A8/SOX4/LRP2/RAB8B/TCF7L2/PSAP/FAM3B 13 GO:0001913 T cell mediated cytotoxicity 4/445 49/18722 0.0287854965871893 0.168193615843959 HLA-B/HLA-DRA/HLA-DRB1/HLA-A 4 GO:0006376 mRNA splice site selection 4/445 49/18722 0.0287854965871893 0.168193615843959 SFSWAP/SRSF5/YTHDC1/SRSF9 4 GO:0006692 prostanoid metabolic process 4/445 49/18722 0.0287854965871893 0.168193615843959 CD74/ANXA1/GSTP1/HPGD 4 GO:0006693 prostaglandin metabolic process 4/445 49/18722 0.0287854965871893 0.168193615843959 CD74/ANXA1/GSTP1/HPGD 4 GO:0009409 response to cold 4/445 49/18722 0.0287854965871893 0.168193615843959 FOS/HSPA2/EIF2AK4/DNAJC3 4 GO:0043457 regulation of cellular respiration 4/445 49/18722 0.0287854965871893 0.168193615843959 BNIP3/IFNAR1/PIK3CA/RHOA 4 GO:0023061 signal release 18/445 463/18722 0.0289023260512217 0.168637724459882 WNT7A/CGA/SFRP1/HLA-DRB1/RAP1B/SPP1/SRI/ANXA1/INHA/SOX4/TMF1/CTBP2/RAB8B/TCF7L2/GATA3/VAMP8/FAM3B/RAB11FIP1 18 GO:0031056 regulation of histone modification 8/445 152/18722 0.0290297347345587 0.169142220294022 CTNNB1/ING2/TAF7/IWS1/SMARCB1/RTF1/BRD7/GATA3 8 GO:1905952 regulation of lipid localization 9/445 181/18722 0.0293640687944758 0.170030148521113 APOE/APOC1/PLIN2/SPP1/RXRA/TMF1/HILPDA/PPARG/DBI 9 GO:0002367 cytokine production involved in immune response 6/445 98/18722 0.0294290864663751 0.170030148521113 CD74/HMOX1/HLA-A/SLC7A5/LAPTM5/GATA3 6 GO:0032642 regulation of chemokine production 6/445 98/18722 0.0294290864663751 0.170030148521113 KLF4/CD74/HMOX1/GSTP1/EIF2AK2/AIF1 6 GO:0070301 cellular response to hydrogen peroxide 6/445 98/18722 0.0294290864663751 0.170030148521113 KLF4/ANXA1/PAWR/BNIP3/RHOB/NET1 6 GO:1902882 regulation of response to oxidative stress 6/445 98/18722 0.0294290864663751 0.170030148521113 PAGE4/CTNNB1/PAWR/MAPKAP1/MCL1/ATF4 6 GO:1904029 regulation of cyclin-dependent protein kinase activity 6/445 98/18722 0.0294290864663751 0.170030148521113 CCNL1/CCNG2/HSP90AB1/CDC37/RGCC/CCNI 6 GO:0044843 cell cycle G1/S phase transition 11/445 241/18722 0.0297464385782856 0.171623656099019 KLF4/ANXA1/ADAMTS1/SOX4/PLK2/AIF1/KHDRBS1/BRD7/RDX/RGCC/WEE1 11 GO:0086003 cardiac muscle cell contraction 5/445 73/18722 0.0298103618151291 0.171704944833102 SRI/GSN/PKP2/PIK3CA/DSP 5 GO:0060070 canonical Wnt signaling pathway 13/445 303/18722 0.0298436578044462 0.171704944833102 APOE/KLF4/STK3/WNT7A/SFRP1/CTNNB1/RPS12/SOX4/WNK1/PLPP3/WWTR1/TCF7L2/GATA3 13 GO:0052548 regulation of endopeptidase activity 17/445 432/18722 0.02998704562962 0.172289965919277 KLF4/SPINT1/NLRP2/S100A9/S100A8/TNFAIP8/GSN/PAK2/CST6/BIRC7/SERPINF1/CST3/CTSD/PPARG/RHOA/LAPTM5/PDCD6 17 GO:0071692 protein localization to extracellular region 15/445 368/18722 0.0306824162465682 0.175043155929151 APOE/SFRP1/FBN2/HLA-DRB1/SRI/ANXA1/SOX4/DNAJC1/ARFGAP3/IER3IP1/RAB8B/GOLPH3/TCF7L2/FAM3B/RAB11FIP1 15 GO:0009749 response to glucose 10/445 212/18722 0.0306842436818849 0.175043155929151 HLA-DRB1/SRI/LDHA/SMARCB1/SOX4/TXNIP/SERPINF1/PIK3CA/RHOA/TCF7L2 10 GO:0050873 brown fat cell differentiation 4/445 50/18722 0.0307210016814225 0.175043155929151 CEBPB/ERO1A/PIM1/BNIP3 4 GO:1904036 negative regulation of epithelial cell apoptotic process 4/445 50/18722 0.0307210016814225 0.175043155929151 HMOX1/ANGPTL4/TCF7L2/GATA3 4 GO:0031341 regulation of cell killing 6/445 99/18722 0.0307250300842243 0.175043155929151 HLA-B/HLA-DRA/HLA-DRB1/TYROBP/HLA-A/HSP90AB1 6 GO:0032602 chemokine production 6/445 99/18722 0.0307250300842243 0.175043155929151 KLF4/CD74/HMOX1/GSTP1/EIF2AK2/AIF1 6 GO:0035066 positive regulation of histone acetylation 3/445 29/18722 0.0308475956224696 0.175043155929151 SMARCB1/BRD7/GATA3 3 GO:0050686 negative regulation of mRNA processing 3/445 29/18722 0.0308475956224696 0.175043155929151 SFSWAP/SRSF4/SRSF9 3 GO:2000406 positive regulation of T cell migration 3/445 29/18722 0.0308475956224696 0.175043155929151 WNK1/AIF1/RHOA 3 GO:0050770 regulation of axonogenesis 8/445 154/18722 0.0310393594041571 0.175889703290223 SKIL/WNT7A/SPP1/SEMA4C/SHTN1/GOLGA4/PAK2/MACF1 8 GO:0002819 regulation of adaptive immune response 9/445 183/18722 0.0311981556714606 0.175987016855403 HLA-B/HLA-DRA/HLA-DRB1/ANXA1/EIF2AK4/IRF1/HLA-A/GATA3/NFKBIZ 9 GO:0050900 leukocyte migration 15/445 369/18722 0.0313162573836267 0.175987016855403 CD74/S100A9/ANXA1/HMOX1/S100A8/SBDS/FCER1G/MTUS1/WNK1/RPS19/AIF1/CALR/RHOA/GOLPH3/GATA3 15 GO:1903201 regulation of oxidative stress-induced cell death 5/445 74/18722 0.031370285964393 0.175987016855403 PAGE4/CTNNB1/PAWR/MCL1/ATF4 5 GO:0002424 T cell mediated immune response to tumor cell 2/445 12/18722 0.03178075879306 0.175987016855403 HLA-DRB1/HLA-A 2 GO:0009886 post-embryonic animal morphogenesis 2/445 12/18722 0.03178075879306 0.175987016855403 HMGN1/EFEMP1 2 GO:0034333 adherens junction assembly 2/445 12/18722 0.03178075879306 0.175987016855403 CTNNB1/PAK2 2 GO:0043380 regulation of memory T cell differentiation 2/445 12/18722 0.03178075879306 0.175987016855403 HLA-DRA/HLA-DRB1 2 GO:0046831 regulation of RNA export from nucleus 2/445 12/18722 0.03178075879306 0.175987016855403 IWS1/KHDRBS1 2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation 2/445 12/18722 0.03178075879306 0.175987016855403 PMEPA1/PPARG 2 GO:0060907 positive regulation of macrophage cytokine production 2/445 12/18722 0.03178075879306 0.175987016855403 CD74/LAPTM5 2 GO:0061430 bone trabecula morphogenesis 2/445 12/18722 0.03178075879306 0.175987016855403 SFRP1/FBN2 2 GO:0071635 negative regulation of transforming growth factor beta production 2/445 12/18722 0.03178075879306 0.175987016855403 TYROBP/HSP90AB1 2 GO:0072537 fibroblast activation 2/445 12/18722 0.03178075879306 0.175987016855403 AKAP12/RGCC 2 GO:0098911 regulation of ventricular cardiac muscle cell action potential 2/445 12/18722 0.03178075879306 0.175987016855403 PKP2/DSP 2 GO:1902950 regulation of dendritic spine maintenance 2/445 12/18722 0.03178075879306 0.175987016855403 APOE/ZMYND8 2 GO:1904667 negative regulation of ubiquitin protein ligase activity 2/445 12/18722 0.03178075879306 0.175987016855403 RPS15/RPL23 2 GO:1904816 positive regulation of protein localization to chromosome, telomeric region 2/445 12/18722 0.03178075879306 0.175987016855403 GNL3/CCT6A 2 GO:0046545 development of primary female sexual characteristics 6/445 100/18722 0.0320577326311492 0.176936447853131 CEBPB/SFRP1/INHA/ADAMTS1/CTNNA1/NRIP1 6 GO:1903364 positive regulation of cellular protein catabolic process 8/445 155/18722 0.0320790739060039 0.176936447853131 APOE/GABARAP/LRP2/UBE2V2/HSPA1B/PLK2/RDX/LAPTM5 8 GO:0030048 actin filament-based movement 7/445 127/18722 0.032123538099697 0.176936447853131 TPM1/SRI/GSN/SHTN1/PKP2/PIK3CA/DSP 7 GO:0051224 negative regulation of protein transport 7/445 127/18722 0.032123538099697 0.176936447853131 APOE/SFRP1/ANXA1/GOPC/SP100/UBE2J1/RAB11FIP1 7 GO:0001666 response to hypoxia 13/445 307/18722 0.0326703848247034 0.179090193646916 SFRP1/LDHA/ERO1A/BNIP3/HMOX1/BNIP3L/NDRG1/GNB1/ANGPTL4/HILPDA/PLOD2/RGCC/RHOA 13 GO:0006120 mitochondrial electron transport, NADH to ubiquinone 4/445 51/18722 0.0327314185402625 0.179090193646916 NDUFB2/NDUFA3/NDUFB1/NDUFA4 4 GO:0032873 negative regulation of stress-activated MAPK cascade 4/445 51/18722 0.0327314185402625 0.179090193646916 SFRP1/AIDA/GSTP1/DNAJA1 4 GO:0045104 intermediate filament cytoskeleton organization 4/445 51/18722 0.0327314185402625 0.179090193646916 VIM/PKP2/MACF1/DSP 4 GO:0070303 negative regulation of stress-activated protein kinase signaling cascade 4/445 51/18722 0.0327314185402625 0.179090193646916 SFRP1/AIDA/GSTP1/DNAJA1 4 GO:0002697 regulation of immune effector process 14/445 339/18722 0.0327746759615271 0.179090193646916 CD74/HLA-B/HLA-DRA/HLA-DRB1/TYROBP/ANXA1/HMOX1/HLA-A/RPS19/SLC7A5/LAPTM5/GATA3/VAMP8/NFKBIZ 14 GO:0002040 sprouting angiogenesis 9/445 185/18722 0.0331105345838511 0.180621356454606 KLF4/EPN2/ANXA1/RNF213/HMOX1/PLK2/TJP1/JAK1/RHOA 9 GO:0046631 alpha-beta T cell activation 8/445 156/18722 0.0331423355586035 0.180621356454606 HLA-DRA/HLA-DRB1/ANXA1/IRF1/HLA-A/RHOA/GATA3/NFKBIZ 8 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 7/445 128/18722 0.0333171259695959 0.18133471328116 SKIL/FBN2/ING2/PMEPA1/HSP90AB1/PEG10/PPARG 7 GO:0042102 positive regulation of T cell proliferation 6/445 101/18722 0.0334275063798411 0.181696090598847 ANXA1/SLC7A1/HLA-DPA1/HLA-A/HLA-DPB1/AIF1 6 GO:0045940 positive regulation of steroid metabolic process 3/445 30/18722 0.0336874084153688 0.18286817892758 APOE/APOC1/CGA 3 GO:0031100 animal organ regeneration 5/445 76/18722 0.0346411706863477 0.187553626446688 CEBPB/HMOX1/GSTP1/SRSF5/RPS15 5 GO:0031103 axon regeneration 4/445 52/18722 0.0348170335606252 0.187553626446688 KLF4/SPP1/RTN4RL2/CTNNA1 4 GO:0032206 positive regulation of telomere maintenance 4/445 52/18722 0.0348170335606252 0.187553626446688 GNL3/CTNNB1/HNRNPA1/CCT6A 4 GO:0045103 intermediate filament-based process 4/445 52/18722 0.0348170335606252 0.187553626446688 VIM/PKP2/MACF1/DSP 4 GO:0032677 regulation of interleukin-8 production 6/445 102/18722 0.0348346474303635 0.187553626446688 KLF4/CD74/TMSB4X/ANXA1/ANXA4/HSPA1B 6 GO:1902106 negative regulation of leukocyte differentiation 6/445 102/18722 0.0348346474303635 0.187553626446688 CD74/SFRP1/CTNNB1/ANXA1/INHA/IRF1 6 GO:0051047 positive regulation of secretion 13/445 310/18722 0.0349137590746801 0.187553626446688 HLA-DRB1/SPP1/SRI/INHA/S100A8/SOX4/TMF1/IER3IP1/RAB8B/RGCC/GOLPH3/TCF7L2/VAMP8 13 GO:0060326 cell chemotaxis 13/445 310/18722 0.0349137590746801 0.187553626446688 CD74/TMSB4X/S100A9/ANXA1/S100A8/GSTP1/SBDS/FCER1G/MTUS1/WNK1/RPS19/AIF1/CALR 13 GO:0051028 mRNA transport 7/445 130/18722 0.0357921435652848 0.191202044267873 NUTF2/IWS1/NUP58/SMG1/EIF4A3/YTHDC1/HNRNPA1 7 GO:0032637 interleukin-8 production 6/445 103/18722 0.0362794355458106 0.191202044267873 KLF4/CD74/TMSB4X/ANXA1/ANXA4/HSPA1B 6 GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 11/445 249/18722 0.036403603987382 0.191202044267873 CD74/CTNNB1/HLA-DRB1/UBE2V1/HMOX1/LITAF/GSTP1/RIOK3/CPNE1/PLK2/RHOA 11 GO:0002828 regulation of type 2 immune response 3/445 31/18722 0.0366581168622832 0.191202044267873 CD74/ANXA1/GATA3 3 GO:0030201 heparan sulfate proteoglycan metabolic process 3/445 31/18722 0.0366581168622832 0.191202044267873 CTNNB1/HS6ST1/TCF7L2 3 GO:0035115 embryonic forelimb morphogenesis 3/445 31/18722 0.0366581168622832 0.191202044267873 OSR2/WNT7A/CTNNB1 3 GO:0036475 neuron death in response to oxidative stress 3/445 31/18722 0.0366581168622832 0.191202044267873 CTNNB1/MCL1/ATF4 3 GO:0045066 regulatory T cell differentiation 3/445 31/18722 0.0366581168622832 0.191202044267873 HLA-DRA/HLA-DRB1/IRF1 3 GO:0051569 regulation of histone H3-K4 methylation 3/445 31/18722 0.0366581168622832 0.191202044267873 CTNNB1/RTF1/GATA3 3 GO:0043620 regulation of DNA-templated transcription in response to stress 4/445 53/18722 0.0369780592842264 0.191202044267873 CEBPB/HMOX1/JUN/ATF4 4 GO:2000772 regulation of cellular senescence 4/445 53/18722 0.0369780592842264 0.191202044267873 ING2/PAWR/YBX1/PLK2 4 GO:0010917 negative regulation of mitochondrial membrane potential 2/445 13/18722 0.0369783455341403 0.191202044267873 BNIP3/BNIP3L 2 GO:0014029 neural crest formation 2/445 13/18722 0.0369783455341403 0.191202044267873 SFRP1/PDCD6 2 GO:0015801 aromatic amino acid transport 2/445 13/18722 0.0369783455341403 0.191202044267873 SLC7A1/SLC7A5 2 GO:0031392 regulation of prostaglandin biosynthetic process 2/445 13/18722 0.0369783455341403 0.191202044267873 CD74/ANXA1 2 GO:0033689 negative regulation of osteoblast proliferation 2/445 13/18722 0.0369783455341403 0.191202044267873 SFRP1/EIF2AK2 2 GO:0033700 phospholipid efflux 2/445 13/18722 0.0369783455341403 0.191202044267873 APOE/APOC1 2 GO:0042769 DNA damage response, detection of DNA damage 2/445 13/18722 0.0369783455341403 0.191202044267873 SOX4/DNAJA1 2 GO:0043379 memory T cell differentiation 2/445 13/18722 0.0369783455341403 0.191202044267873 HLA-DRA/HLA-DRB1 2 GO:0043970 histone H3-K9 acetylation 2/445 13/18722 0.0369783455341403 0.191202044267873 SMARCB1/GATA3 2 GO:0051451 myoblast migration 2/445 13/18722 0.0369783455341403 0.191202044267873 ANXA1/NET1 2 GO:0060347 heart trabecula formation 2/445 13/18722 0.0369783455341403 0.191202044267873 ADAMTS1/FHL2 2 GO:0060670 branching involved in labyrinthine layer morphogenesis 2/445 13/18722 0.0369783455341403 0.191202044267873 SPINT1/GRB2 2 GO:0070486 leukocyte aggregation 2/445 13/18722 0.0369783455341403 0.191202044267873 S100A9/S100A8 2 GO:0071801 regulation of podosome assembly 2/445 13/18722 0.0369783455341403 0.191202044267873 GSN/RHOA 2 GO:0090161 Golgi ribbon formation 2/445 13/18722 0.0369783455341403 0.191202044267873 GOLGA2/GOLPH3 2 GO:1900272 negative regulation of long-term synaptic potentiation 2/445 13/18722 0.0369783455341403 0.191202044267873 APOE/TYROBP 2 GO:2001198 regulation of dendritic cell differentiation 2/445 13/18722 0.0369783455341403 0.191202044267873 HLA-B/CEBPB 2 GO:0009746 response to hexose 10/445 219/18722 0.0370595834817708 0.191202044267873 HLA-DRB1/SRI/LDHA/SMARCB1/SOX4/TXNIP/SERPINF1/PIK3CA/RHOA/TCF7L2 10 GO:0000723 telomere maintenance 7/445 131/18722 0.0370740347273218 0.191202044267873 GNL3/CTNNB1/SP100/SMG1/HSP90AB1/HNRNPA1/CCT6A 7 GO:0046683 response to organophosphorus 7/445 131/18722 0.0370740347273218 0.191202044267873 FOS/RAP1B/LDHA/JUN/FOSB/FDX1/SPARC 7 GO:1903844 regulation of cellular response to transforming growth factor beta stimulus 7/445 131/18722 0.0370740347273218 0.191202044267873 SKIL/FBN2/ING2/PMEPA1/HSP90AB1/PEG10/PPARG 7 GO:0006892 post-Golgi vesicle-mediated transport 6/445 104/18722 0.0377621340059634 0.194265723011998 AP3S1/GOPC/GOLGA4/MACF1/LAPTM5/GOLPH3 6 GO:1901890 positive regulation of cell junction assembly 6/445 104/18722 0.0377621340059634 0.194265723011998 WNT7A/SFRP1/FERMT2/UBE2V2/LIMS1/CLDN19 6 GO:1903532 positive regulation of secretion by cell 12/445 282/18722 0.0379136765676279 0.194802733707551 HLA-DRB1/SPP1/SRI/INHA/SOX4/TMF1/IER3IP1/RAB8B/RGCC/GOLPH3/TCF7L2/VAMP8 12 GO:0002064 epithelial cell development 10/445 220/18722 0.0380398917573911 0.194870769650961 MYADM/WNT7A/VIM/RAP1B/FNDC3A/VEZF1/TJP1/KLF5/ATF4/RDX 10 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process 5/445 78/18722 0.0381156092660315 0.194870769650961 S100A9/S100A8/PPARG/LAPTM5/PDCD6 5 GO:0043537 negative regulation of blood vessel endothelial cell migration 5/445 78/18722 0.0381156092660315 0.194870769650961 APOE/KLF4/PPARG/RGCC/RHOA 5 GO:0090049 regulation of cell migration involved in sprouting angiogenesis 5/445 78/18722 0.0381156092660315 0.194870769650961 KLF4/ANXA1/HMOX1/PLK2/RHOA 5 GO:0007569 cell aging 7/445 132/18722 0.038385805930439 0.196009597402526 ING2/MORC3/PAWR/YBX1/LIMS1/PLK2/CALR 7 GO:0070482 response to oxygen levels 14/445 347/18722 0.0386706347473879 0.197220237211678 SFRP1/LDHA/ERO1A/BNIP3/HMOX1/BNIP3L/NDRG1/GNB1/CBL/ANGPTL4/HILPDA/PLOD2/RGCC/RHOA 14 GO:0010810 regulation of cell-substrate adhesion 10/445 221/18722 0.0390379830398089 0.198603334898338 PLEKHA2/MYADM/SFRP1/FERMT2/LIMS1/CCDC80/MACF1/CALR/GBP1/RHOA 10 GO:1903050 regulation of proteolysis involved in cellular protein catabolic process 10/445 221/18722 0.0390379830398089 0.198603334898338 APOE/GABARAP/RYBP/RPL23/TMF1/UBE2V2/HSP90AB1/HSPA1B/PLK2/LAPTM5 10 GO:0043434 response to peptide hormone 16/445 414/18722 0.0396564122419476 0.201501400948937 JUND/CA2/AP3S1/RAP1B/ANXA1/GSTP1/SRSF4/SRSF5/GRB2/PIK3CA/PPARG/RAB8B/CSH1/GGH/ZNF106/SPARC 16 GO:0046328 regulation of JNK cascade 7/445 133/18722 0.0397276639681387 0.201524911360795 STK3/WNT7A/SFRP1/AIDA/GSTP1/RB1CC1/DNAJA1 7 GO:0060914 heart formation 3/445 32/18722 0.0397586063323767 0.201524911360795 CTNNB1/PIM1/LRP2 3 GO:0000245 spliceosomal complex assembly 5/445 79/18722 0.0399298554236115 0.202144893082033 SFSWAP/SRSF5/SCAF11/YTHDC1/SRSF9 5 GO:0015931 nucleobase-containing compound transport 10/445 222/18722 0.0400539825015677 0.202495049601151 SLC25A24/NUTF2/IWS1/NUP58/SMG1/YBX1/EIF4A3/YTHDC1/HNRNPA1/KHDRBS1 10 GO:0034612 response to tumor necrosis factor 11/445 253/18722 0.0400970589624163 0.202495049601151 TMSB4X/KRT8/SFRP1/GSTP1/CPNE1/LIMS1/HSPA1B/AKAP12/GBP1/LAPTM5/GATA3 11 GO:0016049 cell growth 18/445 482/18722 0.0403469245005707 0.203508113689692 APOE/TSPYL2/SFRP1/CTNNB1/SPP1/S100A9/SEMA4C/S100A8/CPNE1/SHTN1/GOLGA4/EIF2AK4/NET1/HSP90AB1/HSPA1B/MACF1/RHOA/CDA 18 GO:0002793 positive regulation of peptide secretion 6/445 106/18722 0.0408422319088652 0.205005176203551 HLA-DRB1/SRI/S100A8/SOX4/RAB8B/TCF7L2 6 GO:0035821 modulation of process of other organism 6/445 106/18722 0.0408422319088652 0.205005176203551 APOE/S100A9/SMARCB1/JUN/RXRA/EIF2AK4 6 GO:1903707 negative regulation of hemopoiesis 6/445 106/18722 0.0408422319088652 0.205005176203551 CD74/SFRP1/CTNNB1/ANXA1/INHA/IRF1 6 GO:2000278 regulation of DNA biosynthetic process 6/445 106/18722 0.0408422319088652 0.205005176203551 KLF4/CTNNB1/HSP90AB1/HNRNPA1/CCT6A/RGCC 6 GO:0003229 ventricular cardiac muscle tissue development 4/445 55/18722 0.0415268323902176 0.206227212806268 TPM1/PKP2/LRP2/DSP 4 GO:0006360 transcription by RNA polymerase I 4/445 55/18722 0.0415268323902176 0.206227212806268 POLR2L/NCL/SMARCB1/ATF4 4 GO:0009791 post-embryonic development 5/445 80/18722 0.0417957590526468 0.206227212806268 KLF4/MORC3/HMGN1/EFEMP1/GATA3 5 GO:0032204 regulation of telomere maintenance 5/445 80/18722 0.0417957590526468 0.206227212806268 GNL3/CTNNB1/SMG1/HNRNPA1/CCT6A 5 GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 6/445 107/18722 0.0424400744244271 0.206227212806268 HLA-B/HLA-DRA/HLA-DRB1/HLA-A/GATA3/NFKBIZ 6 GO:0007229 integrin-mediated signaling pathway 6/445 107/18722 0.0424400744244271 0.206227212806268 ADAMTS1/FERMT2/LIMS1/CD63/PLPP3/CTNNA1 6 GO:0010927 cellular component assembly involved in morphogenesis 6/445 107/18722 0.0424400744244271 0.206227212806268 KRT19/TPM1/KRT8/CSRP1/TMOD3/TMF1 6 GO:0001711 endodermal cell fate commitment 2/445 14/18722 0.042475737842492 0.206227212806268 CTNNB1/RTF1 2 GO:0006596 polyamine biosynthetic process 2/445 14/18722 0.042475737842492 0.206227212806268 SAT1/AMD1 2 GO:0010872 regulation of cholesterol esterification 2/445 14/18722 0.042475737842492 0.206227212806268 APOE/APOC1 2 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway 2/445 14/18722 0.042475737842492 0.206227212806268 EPN2/PDCD6 2 GO:0031468 nuclear membrane reassembly 2/445 14/18722 0.042475737842492 0.206227212806268 ANKLE2/UBXN2A 2 GO:0035563 positive regulation of chromatin binding 2/445 14/18722 0.042475737842492 0.206227212806268 CTBP2/MBD2 2 GO:0036151 phosphatidylcholine acyl-chain remodeling 2/445 14/18722 0.042475737842492 0.206227212806268 LPCAT1/DBI 2 GO:0044154 histone H3-K14 acetylation 2/445 14/18722 0.042475737842492 0.206227212806268 PHF14/GATA3 2 GO:0045837 negative regulation of membrane potential 2/445 14/18722 0.042475737842492 0.206227212806268 BNIP3/BNIP3L 2 GO:0050872 white fat cell differentiation 2/445 14/18722 0.042475737842492 0.206227212806268 CTBP2/PPARG 2 GO:0051645 Golgi localization 2/445 14/18722 0.042475737842492 0.206227212806268 ARHGAP21/YWHAZ 2 GO:0061709 reticulophagy 2/445 14/18722 0.042475737842492 0.206227212806268 RB1CC1/UFC1 2 GO:0070278 extracellular matrix constituent secretion 2/445 14/18722 0.042475737842492 0.206227212806268 IER3IP1/RGCC 2 GO:0071481 cellular response to X-ray 2/445 14/18722 0.042475737842492 0.206227212806268 SFRP1/GATA3 2 GO:0072498 embryonic skeletal joint development 2/445 14/18722 0.042475737842492 0.206227212806268 OSR2/CTNNB1 2 GO:0090715 immunological memory formation process 2/445 14/18722 0.042475737842492 0.206227212806268 HLA-DRA/HLA-DRB1 2 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 2/445 14/18722 0.042475737842492 0.206227212806268 CD74/ING2 2 GO:1902916 positive regulation of protein polyubiquitination 2/445 14/18722 0.042475737842492 0.206227212806268 GABARAP/UBE2D1 2 GO:1904814 regulation of protein localization to chromosome, telomeric region 2/445 14/18722 0.042475737842492 0.206227212806268 GNL3/CCT6A 2 GO:2001140 positive regulation of phospholipid transport 2/445 14/18722 0.042475737842492 0.206227212806268 APOE/DBI 2 GO:2000058 regulation of ubiquitin-dependent protein catabolic process 8/445 164/18722 0.0425191778176877 0.206227212806268 GABARAP/RYBP/RPL23/UBE2V2/HSP90AB1/HSPA1B/PLK2/LAPTM5 8 GO:0002285 lymphocyte activation involved in immune response 9/445 194/18722 0.0427201978099159 0.206227212806268 CD74/HLA-DRA/HLA-DRB1/ANXA1/FCER1G/EIF2AK4/PLCL2/GATA3/NFKBIZ 9 GO:0002431 Fc receptor mediated stimulatory signaling pathway 3/445 33/18722 0.0429875833596791 0.206227212806268 VAV2/FCER1G/PLSCR1 3 GO:0010165 response to X-ray 3/445 33/18722 0.0429875833596791 0.206227212806268 SFRP1/ANXA1/GATA3 3 GO:0042558 pteridine-containing compound metabolic process 3/445 33/18722 0.0429875833596791 0.206227212806268 MTHFD1L/PTS/GGH 3 GO:0045920 negative regulation of exocytosis 3/445 33/18722 0.0429875833596791 0.206227212806268 RAP1B/ANXA1/HMOX1 3 GO:0071295 cellular response to vitamin 3/445 33/18722 0.0429875833596791 0.206227212806268 SFRP1/PIM1/TRIM24 3 GO:0150117 positive regulation of cell-substrate junction organization 3/445 33/18722 0.0429875833596791 0.206227212806268 SFRP1/FERMT2/LIMS1 3 GO:1901099 negative regulation of signal transduction in absence of ligand 3/445 33/18722 0.0429875833596791 0.206227212806268 HSPA1B/MCL1/CTNNA1 3 GO:1903146 regulation of autophagy of mitochondrion 3/445 33/18722 0.0429875833596791 0.206227212806268 HAX1/BNIP3/BNIP3L 3 GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 3/445 33/18722 0.0429875833596791 0.206227212806268 HSPA1B/MCL1/CTNNA1 3 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 11/445 256/18722 0.0430326452285169 0.206227212806268 SKIL/SFRP1/FBN2/ING2/INHA/UBE2D1/PMEPA1/LRP2/HSP90AB1/PEG10/PPARG 11 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 5/445 81/18722 0.0437135100199419 0.209005219782847 SKIL/FBN2/PMEPA1/PEG10/PPARG 5 GO:0051817 modulation of process of other organism involved in symbiotic interaction 5/445 81/18722 0.0437135100199419 0.209005219782847 APOE/SMARCB1/JUN/RXRA/EIF2AK4 5 GO:0031529 ruffle organization 4/445 56/18722 0.0439146488160184 0.209048108467041 TPM1/LIMA1/AIF1/RDX 4 GO:0042733 embryonic digit morphogenesis 4/445 56/18722 0.0439146488160184 0.209048108467041 OSR2/WNT7A/CTNNB1/TMEM107 4 GO:0043388 positive regulation of DNA binding 4/445 56/18722 0.0439146488160184 0.209048108467041 KLF4/CTNNB1/PPARG/GATA3 4 GO:1900180 regulation of protein localization to nucleus 7/445 136/18722 0.0439356796831306 0.209048108467041 NUTF2/NUP58/FERMT2/HSP90AB1/WWTR1/CTNNA1/CCT6A 7 GO:0030217 T cell differentiation 11/445 257/18722 0.0440432473821488 0.209048108467041 CD74/HLA-DRA/CTNNB1/HLA-DRB1/ANXA1/FCER1G/SOX4/IRF1/RHOA/GATA3/NFKBIZ 11 GO:0002832 negative regulation of response to biotic stimulus 6/445 108/18722 0.0440767132594512 0.209048108467041 HLA-B/RIOK3/HLA-A/PARP14/RPS19/PPARG 6 GO:0034446 substrate adhesion-dependent cell spreading 6/445 108/18722 0.0440767132594512 0.209048108467041 MYADM/FERMT2/LIMS1/CALR/GBP1/RHOA 6 GO:0007266 Rho protein signal transduction 7/445 137/18722 0.0453997558444819 0.214583971846172 APOE/CDC42EP3/ARHGAP29/RHOB/SHTN1/NET1/RHOA 7 GO:0050671 positive regulation of lymphocyte proliferation 7/445 137/18722 0.0453997558444819 0.214583971846172 CD74/ANXA1/SLC7A1/HLA-DPA1/HLA-A/HLA-DPB1/AIF1 7 GO:0060048 cardiac muscle contraction 7/445 137/18722 0.0453997558444819 0.214583971846172 TPM1/TNNI2/SRI/GSN/PKP2/PIK3CA/DSP 7 GO:0001910 regulation of leukocyte mediated cytotoxicity 5/445 82/18722 0.0456832665431029 0.215099001549306 HLA-B/HLA-DRA/HLA-DRB1/TYROBP/HLA-A 5 GO:0006091 generation of precursor metabolites and energy 18/445 490/18722 0.0460399350583208 0.215099001549306 LDHA/PHLDA2/BNIP3/IFNAR1/UQCR10/UQCRQ/FDX1/RB1CC1/COX6C/PIK3CA/COX7C/NDUFB2/RHOA/NDUFA3/COX6A1/NDUFB1/NDUFA4/COX4I1 18 GO:0016236 macroautophagy 12/445 291/18722 0.0462308690094051 0.215099001549306 ATG12/UBXN2A/GABARAP/BNIP3/HMOX1/BNIP3L/SMG1/RB1CC1/CDC37/PIK3CA/VAMP8/UFC1 12 GO:0010952 positive regulation of peptidase activity 9/445 197/18722 0.0463009023799626 0.215099001549306 NLRP2/S100A9/S100A8/GSN/CTSD/PPARG/RHOA/LAPTM5/PDCD6 9 GO:0042594 response to starvation 9/445 197/18722 0.0463009023799626 0.215099001549306 PAGE4/SFRP1/GABARAP/EIF2AK2/JUN/EIF2AK4/CBL/HNRNPA1/ATF4 9 GO:0016242 negative regulation of macroautophagy 3/445 34/18722 0.0463435884376485 0.215099001549306 HMOX1/SMG1/PIK3CA 3 GO:0032212 positive regulation of telomere maintenance via telomerase 3/445 34/18722 0.0463435884376485 0.215099001549306 CTNNB1/HNRNPA1/CCT6A 3 GO:0035137 hindlimb morphogenesis 3/445 34/18722 0.0463435884376485 0.215099001549306 OSR2/WNT7A/CTNNB1 3 GO:0044319 wound healing, spreading of cells 3/445 34/18722 0.0463435884376485 0.215099001549306 WNT7A/FERMT2/RHOA 3 GO:0051973 positive regulation of telomerase activity 3/445 34/18722 0.0463435884376485 0.215099001549306 KLF4/CTNNB1/HSP90AB1 3 GO:0055094 response to lipoprotein particle 3/445 34/18722 0.0463435884376485 0.215099001549306 APOE/FCER1G/PPARG 3 GO:0086004 regulation of cardiac muscle cell contraction 3/445 34/18722 0.0463435884376485 0.215099001549306 SRI/PKP2/DSP 3 GO:0090075 relaxation of muscle 3/445 34/18722 0.0463435884376485 0.215099001549306 SRI/GSN/PIK3CA 3 GO:0090505 epiboly involved in wound healing 3/445 34/18722 0.0463435884376485 0.215099001549306 WNT7A/FERMT2/RHOA 3 GO:0006611 protein export from nucleus 4/445 57/18722 0.046378017228946 0.215099001549306 NUTF2/SP100/CALR/TCF7L2 4 GO:0061005 cell differentiation involved in kidney development 4/445 57/18722 0.046378017228946 0.215099001549306 CTNNB1/BASP1/WWTR1/GATA3 4 GO:0007254 JNK cascade 8/445 167/18722 0.0464459717700269 0.215099001549306 STK3/WNT7A/SFRP1/AIDA/GSTP1/SH2D3A/RB1CC1/DNAJA1 8 GO:0031960 response to corticosteroid 8/445 167/18722 0.0464459717700269 0.215099001549306 FOS/ANXA1/GSTP1/FOSB/AIF1/SERPINF1/RHOA/SPARC 8 GO:0032946 positive regulation of mononuclear cell proliferation 7/445 138/18722 0.0468948041140194 0.216679105323164 CD74/ANXA1/SLC7A1/HLA-DPA1/HLA-A/HLA-DPB1/AIF1 7 GO:0044772 mitotic cell cycle phase transition 16/445 424/18722 0.0473948059744394 0.216679105323164 KLF4/ANXA1/PPP2R2D/HSPA2/TMOD3/ADAMTS1/CCNG2/SOX4/PLK2/AIF1/KHDRBS1/BRD7/RDX/RGCC/WEE1/CCNI 16 GO:0061387 regulation of extent of cell growth 6/445 110/18722 0.047467080008874 0.216679105323164 APOE/SPP1/SEMA4C/SHTN1/GOLGA4/MACF1 6 GO:0031397 negative regulation of protein ubiquitination 5/445 83/18722 0.0477051553919841 0.216679105323164 RPS15/RPL23/SOX4/HSPA1B/DNAJA1 5 GO:0043367 CD4-positive, alpha-beta T cell differentiation 5/445 83/18722 0.0477051553919841 0.216679105323164 HLA-DRA/HLA-DRB1/ANXA1/GATA3/NFKBIZ 5 GO:0042176 regulation of protein catabolic process 15/445 391/18722 0.0478041838981097 0.216679105323164 APOE/LPCAT1/UBXN2A/GABARAP/RYBP/RPL23/TMF1/LRP2/UBE2V2/HSP90AB1/HSPA1B/PLK2/CST3/RDX/LAPTM5 15 GO:0002833 positive regulation of response to biotic stimulus 8/445 168/18722 0.0478058746344948 0.216679105323164 HLA-DRB1/TYROBP/RIOK3/PAK2/SASH1/RPS19/PLSCR1/LSM14A 8 GO:0010889 regulation of sequestering of triglyceride 2/445 15/18722 0.0482558162423894 0.216679105323164 PLIN2/PPARG 2 GO:0019511 peptidyl-proline hydroxylation 2/445 15/18722 0.0482558162423894 0.216679105323164 P4HA1/ERO1A 2 GO:0032239 regulation of nucleobase-containing compound transport 2/445 15/18722 0.0482558162423894 0.216679105323164 IWS1/KHDRBS1 2 GO:0032488 Cdc42 protein signal transduction 2/445 15/18722 0.0482558162423894 0.216679105323164 APOE/SHTN1 2 GO:0034638 phosphatidylcholine catabolic process 2/445 15/18722 0.0482558162423894 0.216679105323164 APOC1/GDPD3 2 GO:0042159 lipoprotein catabolic process 2/445 15/18722 0.0482558162423894 0.216679105323164 APOE/CTSD 2 GO:0042559 pteridine-containing compound biosynthetic process 2/445 15/18722 0.0482558162423894 0.216679105323164 MTHFD1L/PTS 2 GO:0042994 cytoplasmic sequestering of transcription factor 2/445 15/18722 0.0482558162423894 0.216679105323164 TMSB4X/SRI 2 GO:0045064 T-helper 2 cell differentiation 2/445 15/18722 0.0482558162423894 0.216679105323164 ANXA1/GATA3 2 GO:0045176 apical protein localization 2/445 15/18722 0.0482558162423894 0.216679105323164 GOPC/RDX 2 GO:0045217 cell-cell junction maintenance 2/445 15/18722 0.0482558162423894 0.216679105323164 FERMT2/TJP1 2 GO:0048308 organelle inheritance 2/445 15/18722 0.0482558162423894 0.216679105323164 GOLGA2/YWHAZ 2 GO:0048313 Golgi inheritance 2/445 15/18722 0.0482558162423894 0.216679105323164 GOLGA2/YWHAZ 2 GO:0071380 cellular response to prostaglandin E stimulus 2/445 15/18722 0.0482558162423894 0.216679105323164 SFRP1/GNB1 2 GO:0086069 bundle of His cell to Purkinje myocyte communication 2/445 15/18722 0.0482558162423894 0.216679105323164 PKP2/DSP 2 GO:0098760 response to interleukin-7 2/445 15/18722 0.0482558162423894 0.216679105323164 HDGF/YBX1 2 GO:0098761 cellular response to interleukin-7 2/445 15/18722 0.0482558162423894 0.216679105323164 HDGF/YBX1 2 GO:1901836 regulation of transcription of nucleolar large rRNA by RNA polymerase I 2/445 15/18722 0.0482558162423894 0.216679105323164 NCL/SMARCB1 2 GO:1902018 negative regulation of cilium assembly 2/445 15/18722 0.0482558162423894 0.216679105323164 ODF2L/MAP4 2 GO:2001138 regulation of phospholipid transport 2/445 15/18722 0.0482558162423894 0.216679105323164 APOE/DBI 2 GO:2001279 regulation of unsaturated fatty acid biosynthetic process 2/445 15/18722 0.0482558162423894 0.216679105323164 CD74/ANXA1 2 GO:0009306 protein secretion 14/445 359/18722 0.0488800723747722 0.218223883494083 APOE/SFRP1/HLA-DRB1/SRI/ANXA1/SOX4/DNAJC1/ARFGAP3/IER3IP1/RAB8B/GOLPH3/TCF7L2/FAM3B/RAB11FIP1 14 GO:0001954 positive regulation of cell-matrix adhesion 4/445 58/18722 0.048916803707461 0.218223883494083 PLEKHA2/SFRP1/FERMT2/LIMS1 4 GO:0010043 response to zinc ion 4/445 58/18722 0.048916803707461 0.218223883494083 CA2/S100A8/MT2A/GGH 4 GO:0010559 regulation of glycoprotein biosynthetic process 4/445 58/18722 0.048916803707461 0.218223883494083 CTNNB1/PAWR/GOLGA2/TCF7L2 4 GO:0042743 hydrogen peroxide metabolic process 4/445 58/18722 0.048916803707461 0.218223883494083 HBA2/HBA1/HBG2/HBB 4 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway 4/445 58/18722 0.048916803707461 0.218223883494083 SKIL/S100A9/S100A8/MCL1 4 GO:0018394 peptidyl-lysine acetylation 8/445 169/18722 0.0491914814992832 0.219212524351175 TAF7/IWS1/SMARCB1/SOX4/PHF14/MORF4L2/BRD7/GATA3 8 GO:0006405 RNA export from nucleus 5/445 84/18722 0.0497792721230969 0.219900757444505 IWS1/SMG1/YTHDC1/HNRNPA1/KHDRBS1 5 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 5/445 84/18722 0.0497792721230969 0.219900757444505 KLF4/SOX4/PLK2/BRD7/WEE1 5 GO:0035592 establishment of protein localization to extracellular region 14/445 360/18722 0.0498080071279037 0.219900757444505 APOE/SFRP1/HLA-DRB1/SRI/ANXA1/SOX4/DNAJC1/ARFGAP3/IER3IP1/RAB8B/GOLPH3/TCF7L2/FAM3B/RAB11FIP1 14 GO:0007020 microtubule nucleation 3/445 35/18722 0.04982500822272 0.219900757444505 CENPJ/GOLGA2/HSPA1B 3 GO:0034331 cell junction maintenance 3/445 35/18722 0.04982500822272 0.219900757444505 FERMT2/CTBP2/TJP1 3 GO:0060236 regulation of mitotic spindle organization 3/445 35/18722 0.04982500822272 0.219900757444505 CCSAP/CHMP5/HSPA1B 3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 3/445 35/18722 0.04982500822272 0.219900757444505 ANXA1/HMOX1/PLK2 3 GO:0090504 epiboly 3/445 35/18722 0.04982500822272 0.219900757444505 WNT7A/FERMT2/RHOA 3 GO:2000403 positive regulation of lymphocyte migration 3/445 35/18722 0.04982500822272 0.219900757444505 WNK1/AIF1/RHOA 3 GO:0048568 embryonic organ development 16/445 427/18722 0.0499112866623673 0.220046451656605 KRT19/MTHFD1L/OSR2/STK3/CEBPB/KRT8/FBN2/CTNNB1/SPINT1/PHLDA2/EFEMP1/EIF4A3/MBD2/GRB2/ATF4/GATA3 16 GO:0052547 regulation of peptidase activity 17/445 461/18722 0.0500018262903189 0.220210601711415 KLF4/SPINT1/NLRP2/S100A9/S100A8/TNFAIP8/GSN/PAK2/CST6/BIRC7/SERPINF1/CST3/CTSD/PPARG/RHOA/LAPTM5/PDCD6 17 GO:0009410 response to xenobiotic stimulus 17/445 462/18722 0.050827978738062 0.223610628505787 FOS/PLIN2/SFRP1/RAP1B/ANXA1/LDHA/HMOX1/GSTP1/JUN/FOSB/ADIRF/HSP90AB1/TXNIP/CALR/GGH/RHOA/GATA3 17 GO:0006402 mRNA catabolic process 10/445 232/18722 0.0512242980577747 0.225114441783689 VIM/PKP3/MEX3D/SMG1/HNRNPM/YBX1/EIF4A3/HSPA1B/SERBP1/HNRNPR 10 GO:0035306 positive regulation of dephosphorylation 4/445 59/18722 0.0515308100082467 0.225461682610421 ANKLE2/PPP1R15A/HSP90AB1/CAMTA1 4 GO:0048010 vascular endothelial growth factor receptor signaling pathway 4/445 59/18722 0.0515308100082467 0.225461682610421 EPN2/VAV2/PAK2/PDCD6 4 GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 4/445 59/18722 0.0515308100082467 0.225461682610421 SFRP1/SH3BP5/PARP14/CBL 4 GO:0051568 histone H3-K4 methylation 4/445 59/18722 0.0515308100082467 0.225461682610421 CTNNB1/KMT2C/RTF1/GATA3 4 GO:0015833 peptide transport 11/445 264/18722 0.0515762019043446 0.225461682610421 CA2/CD74/SFRP1/HLA-DRB1/SRI/ANXA1/S100A8/SOX4/RAB8B/TCF7L2/FAM3B 11 GO:0022613 ribonucleoprotein complex biogenesis 17/445 463/18722 0.0516637098942868 0.22560548157854 MPHOSPH10/SFSWAP/ZNHIT6/SRSF5/RIOK3/RPS15/SBDS/SCAF11/RBFA/EIF4H/EIF4A3/HSP90AB1/RPS19/DENR/YTHDC1/SRSF9/RPS28 17 GO:0002709 regulation of T cell mediated immunity 5/445 85/18722 0.0519056813454614 0.225945594982193 HLA-B/HLA-DRA/HLA-DRB1/HLA-A/GATA3 5 GO:0010507 negative regulation of autophagy 5/445 85/18722 0.0519056813454614 0.225945594982193 HMOX1/GOLGA2/SMG1/MCL1/PIK3CA 5 GO:0055072 iron ion homeostasis 5/445 85/18722 0.0519056813454614 0.225945594982193 FTL/SRI/SLC25A37/HMOX1/SLC40A1 5 GO:0090087 regulation of peptide transport 9/445 202/18722 0.0527026130751058 0.229133795127386 CA2/CD74/SFRP1/HLA-DRB1/SRI/S100A8/SOX4/RAB8B/TCF7L2 9 GO:0042092 type 2 immune response 3/445 36/18722 0.053430087169601 0.229133795127386 CD74/ANXA1/GATA3 3 GO:0060338 regulation of type I interferon-mediated signaling pathway 3/445 36/18722 0.053430087169601 0.229133795127386 HSP90AB1/CDC37/LSM14A 3 GO:0071402 cellular response to lipoprotein particle stimulus 3/445 36/18722 0.053430087169601 0.229133795127386 APOE/FCER1G/PPARG 3 GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage 3/445 36/18722 0.053430087169601 0.229133795127386 CD74/SKIL/ING2 3 GO:0048588 developmental cell growth 10/445 234/18722 0.0536842136466512 0.229133795127386 APOE/CTNNB1/SPP1/SEMA4C/CPNE1/SHTN1/GOLGA4/EIF2AK4/HSP90AB1/MACF1 10 GO:0009798 axis specification 5/445 86/18722 0.0540844170164028 0.229133795127386 WNT7A/SFRP1/CTNNB1/BASP1/ETS2 5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome 4/445 60/18722 0.0542197753272911 0.229133795127386 YTHDC1/HNRNPA1/KHDRBS1/SRSF2 4 GO:0006893 Golgi to plasma membrane transport 4/445 60/18722 0.0542197753272911 0.229133795127386 GOPC/GOLGA4/MACF1/GOLPH3 4 GO:0031102 neuron projection regeneration 4/445 60/18722 0.0542197753272911 0.229133795127386 KLF4/SPP1/RTN4RL2/CTNNA1 4 GO:0051851 modulation by host of symbiont process 4/445 60/18722 0.0542197753272911 0.229133795127386 APOE/SMARCB1/JUN/EIF2AK4 4 GO:0055008 cardiac muscle tissue morphogenesis 4/445 60/18722 0.0542197753272911 0.229133795127386 TPM1/PKP2/LRP2/DSP 4 GO:0061951 establishment of protein localization to plasma membrane 4/445 60/18722 0.0542197753272911 0.229133795127386 GOPC/GOLGA4/MACF1/GOLPH3 4 GO:1903670 regulation of sprouting angiogenesis 4/445 60/18722 0.0542197753272911 0.229133795127386 KLF4/EPN2/TJP1/JAK1 4 GO:0002830 positive regulation of type 2 immune response 2/445 16/18722 0.0543021025005353 0.229133795127386 CD74/GATA3 2 GO:0003084 positive regulation of systemic arterial blood pressure 2/445 16/18722 0.0543021025005353 0.229133795127386 WNK1/RHOA 2 GO:0009048 dosage compensation by inactivation of X chromosome 2/445 16/18722 0.0543021025005353 0.229133795127386 CDYL/YTHDC1 2 GO:0009415 response to water 2/445 16/18722 0.0543021025005353 0.229133795127386 KRT8/PIK3CA 2 GO:0017014 protein nitrosylation 2/445 16/18722 0.0543021025005353 0.229133795127386 S100A9/S100A8 2 GO:0018119 peptidyl-cysteine S-nitrosylation 2/445 16/18722 0.0543021025005353 0.229133795127386 S100A9/S100A8 2 GO:0019081 viral translation 2/445 16/18722 0.0543021025005353 0.229133795127386 EIF2AK4/DENR 2 GO:0033631 cell-cell adhesion mediated by integrin 2/445 16/18722 0.0543021025005353 0.229133795127386 WNK1/PLPP3 2 GO:0034375 high-density lipoprotein particle remodeling 2/445 16/18722 0.0543021025005353 0.229133795127386 APOE/APOC1 2 GO:0043923 positive regulation by host of viral transcription 2/445 16/18722 0.0543021025005353 0.229133795127386 SMARCB1/JUN 2 GO:0044804 autophagy of nucleus 2/445 16/18722 0.0543021025005353 0.229133795127386 ATG12/RB1CC1 2 GO:0048385 regulation of retinoic acid receptor signaling pathway 2/445 16/18722 0.0543021025005353 0.229133795127386 CTBP2/CALR 2 GO:0051014 actin filament severing 2/445 16/18722 0.0543021025005353 0.229133795127386 DSTN/GSN 2 GO:0071391 cellular response to estrogen stimulus 2/445 16/18722 0.0543021025005353 0.229133795127386 SFRP1/TRIM24 2 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 2/445 16/18722 0.0543021025005353 0.229133795127386 CD74/ING2 2 GO:1904948 midbrain dopaminergic neuron differentiation 2/445 16/18722 0.0543021025005353 0.229133795127386 SFRP1/CTNNB1 2 GO:1901990 regulation of mitotic cell cycle phase transition 12/445 299/18722 0.0546136603636226 0.230213296900128 KLF4/ANXA1/HSPA2/TMOD3/ADAMTS1/SOX4/PLK2/AIF1/BRD7/RDX/RGCC/WEE1 12 GO:0048762 mesenchymal cell differentiation 10/445 236/18722 0.0562211263889277 0.235464837353803 SFRP1/CTNNB1/SEMA4C/FERMT2/HNRNPAB/WWTR1/RGCC/TCF7L2/GATA3/PDCD6 10 GO:0090068 positive regulation of cell cycle process 10/445 236/18722 0.0562211263889277 0.235464837353803 ANXA1/HSPA2/TMOD3/ADAMTS1/CENPJ/AIF1/PLSCR1/RDX/RGCC/RHOA 10 GO:0050708 regulation of protein secretion 11/445 268/18722 0.0562487046659277 0.235464837353803 APOE/SFRP1/HLA-DRB1/SRI/ANXA1/SOX4/DNAJC1/IER3IP1/GOLPH3/TCF7L2/RAB11FIP1 11 GO:0019915 lipid storage 5/445 87/18722 0.0563154827658091 0.235464837353803 APOE/PLIN2/HILPDA/PPARG/NRIP1 5 GO:0048041 focal adhesion assembly 5/445 87/18722 0.0563154827658091 0.235464837353803 SFRP1/FERMT2/LIMS1/MACF1/RHOA 5 GO:0150104 transport across blood-brain barrier 5/445 87/18722 0.0563154827658091 0.235464837353803 APOE/SLC2A3/SLC7A1/LRP2/SLC7A5 5 GO:1900182 positive regulation of protein localization to nucleus 5/445 87/18722 0.0563154827658091 0.235464837353803 NUTF2/FERMT2/HSP90AB1/WWTR1/CCT6A 5 GO:2000177 regulation of neural precursor cell proliferation 5/445 87/18722 0.0563154827658091 0.235464837353803 CTNNB1/SPINT1/LRP2/CTNNA1/RHOA 5 GO:0034968 histone lysine methylation 6/445 115/18722 0.0566323975256752 0.236351665105463 CTNNB1/IWS1/SMARCB1/KMT2C/RTF1/GATA3 6 GO:0009615 response to virus 14/445 367/18722 0.056647475772371 0.236351665105463 BNIP3/EIF2AK2/RIOK3/IFNAR1/BNIP3L/EIF2AK4/IRF1/MX1/PLSCR1/LSM14A/DNAJC3/GBP1/GATA3/VAMP8 14 GO:0006900 vesicle budding from membrane 4/445 61/18722 0.0569833780933007 0.236351665105463 CHMP5/ARFGAP3/GOLPH3/PDCD6 4 GO:0030865 cortical cytoskeleton organization 4/445 61/18722 0.0569833780933007 0.236351665105463 RHOB/CALR/RHOA/FMNL2 4 GO:0042255 ribosome assembly 4/445 61/18722 0.0569833780933007 0.236351665105463 RPS15/SBDS/RPS19/RPS28 4 GO:0090342 regulation of cell aging 4/445 61/18722 0.0569833780933007 0.236351665105463 ING2/PAWR/YBX1/PLK2 4 GO:0032570 response to progesterone 3/445 37/18722 0.0571569386202754 0.236351665105463 FOS/FOSB/TXNIP 3 GO:0033120 positive regulation of RNA splicing 3/445 37/18722 0.0571569386202754 0.236351665105463 NCL/SRSF5/RBM3 3 GO:0042401 cellular biogenic amine biosynthetic process 3/445 37/18722 0.0571569386202754 0.236351665105463 SAT1/AMD1/GATA3 3 GO:0043403 skeletal muscle tissue regeneration 3/445 37/18722 0.0571569386202754 0.236351665105463 WNT7A/ANXA1/KLF5 3 GO:1904358 positive regulation of telomere maintenance via telomere lengthening 3/445 37/18722 0.0571569386202754 0.236351665105463 CTNNB1/HNRNPA1/CCT6A 3 GO:0051051 negative regulation of transport 17/445 470/18722 0.0577856729942947 0.238712615139432 APOE/APOC1/CD74/SFRP1/RAP1B/SRI/ANXA1/GOPC/INHA/HMOX1/SP100/SESTD1/WNK1/PLSCR1/UBE2J1/VAMP8/RAB11FIP1 17 GO:0043524 negative regulation of neuron apoptotic process 7/445 145/18722 0.0582383805734861 0.24034240774133 APOE/CEBPB/HMOX1/UBE2V2/HSP90AB1/PIK3CA/RHOA 7 GO:0035967 cellular response to topologically incorrect protein 6/445 116/18722 0.0585844315291662 0.241347815188403 PPP1R15A/ERO1A/HSPA2/EIF2AK2/HSPA1B/ATF4 6 GO:0010232 vascular transport 5/445 88/18722 0.0585988522473901 0.241347815188403 APOE/SLC2A3/SLC7A1/LRP2/SLC7A5 5 GO:0032623 interleukin-2 production 4/445 62/18722 0.0598212377879602 0.244903486127198 ANXA1/GBP1/LAPTM5/GATA3 4 GO:0032663 regulation of interleukin-2 production 4/445 62/18722 0.0598212377879602 0.244903486127198 ANXA1/GBP1/LAPTM5/GATA3 4 GO:0045428 regulation of nitric oxide biosynthetic process 4/445 62/18722 0.0598212377879602 0.244903486127198 KLF4/HSP90AB1/AIF1/HBB 4 GO:0046824 positive regulation of nucleocytoplasmic transport 4/445 62/18722 0.0598212377879602 0.244903486127198 NUTF2/HSP90AB1/KHDRBS1/TCF7L2 4 GO:1903828 negative regulation of cellular protein localization 6/445 117/18722 0.0605762629939773 0.244903486127198 GOPC/SP100/CTNNA1/UBE2J1/GBP1/DNAJA1 6 GO:0006901 vesicle coating 2/445 17/18722 0.0605987389270661 0.244903486127198 ARFGAP3/PDCD6 2 GO:0010934 macrophage cytokine production 2/445 17/18722 0.0605987389270661 0.244903486127198 CD74/LAPTM5 2 GO:0010935 regulation of macrophage cytokine production 2/445 17/18722 0.0605987389270661 0.244903486127198 CD74/LAPTM5 2 GO:0033623 regulation of integrin activation 2/445 17/18722 0.0605987389270661 0.244903486127198 RAP1B/FERMT2 2 GO:0043117 positive regulation of vascular permeability 2/445 17/18722 0.0605987389270661 0.244903486127198 APOE/TJP1 2 GO:0045591 positive regulation of regulatory T cell differentiation 2/445 17/18722 0.0605987389270661 0.244903486127198 HLA-DRA/HLA-DRB1 2 GO:0055119 relaxation of cardiac muscle 2/445 17/18722 0.0605987389270661 0.244903486127198 GSN/PIK3CA 2 GO:0060644 mammary gland epithelial cell differentiation 2/445 17/18722 0.0605987389270661 0.244903486127198 CEBPB/LBH 2 GO:0070293 renal absorption 2/445 17/18722 0.0605987389270661 0.244903486127198 GSN/HBB 2 GO:0090036 regulation of protein kinase C signaling 2/445 17/18722 0.0605987389270661 0.244903486127198 MYADM/AKAP12 2 GO:0090083 regulation of inclusion body assembly 2/445 17/18722 0.0605987389270661 0.244903486127198 HSPA2/HSPA1B 2 GO:0090136 epithelial cell-cell adhesion 2/445 17/18722 0.0605987389270661 0.244903486127198 DSP/CTNNA1 2 GO:0090713 immunological memory process 2/445 17/18722 0.0605987389270661 0.244903486127198 HLA-DRA/HLA-DRB1 2 GO:2000811 negative regulation of anoikis 2/445 17/18722 0.0605987389270661 0.244903486127198 MCL1/PIK3CA 2 GO:0000578 embryonic axis specification 3/445 38/18722 0.0610035553679221 0.244903486127198 WNT7A/CTNNB1/BASP1 3 GO:0006882 cellular zinc ion homeostasis 3/445 38/18722 0.0610035553679221 0.244903486127198 S100A9/S100A8/MT2A 3 GO:0009309 amine biosynthetic process 3/445 38/18722 0.0610035553679221 0.244903486127198 SAT1/AMD1/GATA3 3 GO:0009595 detection of biotic stimulus 3/445 38/18722 0.0610035553679221 0.244903486127198 HLA-B/HLA-DRB1/HLA-A 3 GO:0032373 positive regulation of sterol transport 3/445 38/18722 0.0610035553679221 0.244903486127198 APOE/RXRA/PPARG 3 GO:0032376 positive regulation of cholesterol transport 3/445 38/18722 0.0610035553679221 0.244903486127198 APOE/RXRA/PPARG 3 GO:0035136 forelimb morphogenesis 3/445 38/18722 0.0610035553679221 0.244903486127198 OSR2/WNT7A/CTNNB1 3 GO:0043405 regulation of MAP kinase activity 8/445 177/18722 0.0612147509751932 0.245512753668469 APOE/ARHGEF5/SFRP1/AIDA/GSTP1/SASH1/PPARG/DNAJA1 8 GO:0018209 peptidyl-serine modification 13/445 338/18722 0.0613718258457556 0.245903988912528 PNCK/MORC3/HAX1/MAPKAP1/GALNT1/SH2D3A/SMG1/PAK2/WNK1/HSP90AB1/PLK2/PIK3CA/PLCL2 13 GO:0001889 liver development 7/445 147/18722 0.0617647702212534 0.247238629635657 CEBPB/ANXA1/HMOX1/SRSF5/RPS15/RB1CC1/PIK3CA 7 GO:0045862 positive regulation of proteolysis 14/445 372/18722 0.0619083627058876 0.247573520172335 APOE/NLRP2/S100A9/GABARAP/S100A8/GSN/UBE2V2/HSPA1B/PLK2/CTSD/PPARG/RHOA/LAPTM5/PDCD6 14 GO:0034249 negative regulation of cellular amide metabolic process 11/445 273/18722 0.0624745949090228 0.24959627811332 APOE/NCL/EIF2AK2/MEX3D/EIF2AK4/YBX1/EIF4A3/LSM14A/CALR/HNRNPR/ATF4 11 GO:0045446 endothelial cell differentiation 6/445 118/18722 0.0626079184704248 0.249662504095127 MYADM/CTNNB1/RAP1B/VEZF1/TJP1/RDX 6 GO:0050854 regulation of antigen receptor-mediated signaling pathway 4/445 63/18722 0.0627329167878823 0.249662504095127 PAWR/PLCL2/GBP1/LAPTM5 4 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 4/445 63/18722 0.0627329167878823 0.249662504095127 CEBPB/PPP1R15A/ERO1A/ATF4 4 GO:1904589 regulation of protein import 4/445 63/18722 0.0627329167878823 0.249662504095127 ARHGEF5/NUTF2/NUP58/HSP90AB1 4 GO:0070664 negative regulation of leukocyte proliferation 5/445 90/18722 0.0633222494261136 0.251523281133918 CEBPB/HLA-DRB1/TYROBP/PAWR/GSTP1 5 GO:0099175 regulation of postsynapse organization 5/445 90/18722 0.0633222494261136 0.251523281133918 APOE/WNT7A/TANC2/ZMYND8/SRGN 5 GO:0010212 response to ionizing radiation 7/445 148/18722 0.0635758949986846 0.252046086602271 SFRP1/ANXA1/RHOB/NET1/CBL/GRB2/GATA3 7 GO:0014074 response to purine-containing compound 7/445 148/18722 0.0635758949986846 0.252046086602271 FOS/RAP1B/LDHA/JUN/FOSB/FDX1/SPARC 7 GO:0002790 peptide secretion 10/445 242/18722 0.0642997967006675 0.254671582138502 CD74/SFRP1/HLA-DRB1/SRI/ANXA1/S100A8/SOX4/RAB8B/TCF7L2/FAM3B 10 GO:0045923 positive regulation of fatty acid metabolic process 3/445 39/18722 0.0649678197162082 0.256579410370608 CD74/ANXA1/PPARG 3 GO:0090224 regulation of spindle organization 3/445 39/18722 0.0649678197162082 0.256579410370608 CCSAP/CHMP5/HSPA1B 3 GO:1903115 regulation of actin filament-based movement 3/445 39/18722 0.0649678197162082 0.256579410370608 SRI/PKP2/DSP 3 GO:0032368 regulation of lipid transport 7/445 149/18722 0.0654190328115734 0.257868344031116 APOE/APOC1/SPP1/RXRA/TMF1/PPARG/DBI 7 GO:0045834 positive regulation of lipid metabolic process 7/445 149/18722 0.0654190328115734 0.257868344031116 APOE/APOC1/CD74/CGA/ANXA1/VAV2/PPARG 7 GO:0050807 regulation of synapse organization 9/445 211/18722 0.0656272252972274 0.258208533077874 APOE/WNT7A/TANC2/ZMYND8/YWHAZ/UBE2V2/SRGN/RHOA/SPARC 9 GO:0080164 regulation of nitric oxide metabolic process 4/445 64/18722 0.0657179222234151 0.258208533077874 KLF4/HSP90AB1/AIF1/HBB 4 GO:0002275 myeloid cell activation involved in immune response 5/445 91/18722 0.0657620780605509 0.258208533077874 TYROBP/HMOX1/FCER1G/CBL/VAMP8 5 GO:0032411 positive regulation of transporter activity 6/445 120/18722 0.0667907241623572 0.258208533077874 TMSB4X/HSPA2/RXRA/WNK1/CTSS/NDUFA4 6 GO:0048675 axon extension 6/445 120/18722 0.0667907241623572 0.258208533077874 APOE/SEMA4C/SHTN1/GOLGA4/HSP90AB1/MACF1 6 GO:0071901 negative regulation of protein serine/threonine kinase activity 6/445 120/18722 0.0667907241623572 0.258208533077874 APOE/SFRP1/AIDA/GSTP1/PPARG/DNAJA1 6 GO:0002223 stimulatory C-type lectin receptor signaling pathway 2/445 18/18722 0.0671304682947559 0.258208533077874 TYROBP/PAK2 2 GO:0002283 neutrophil activation involved in immune response 2/445 18/18722 0.0671304682947559 0.258208533077874 TYROBP/FCER1G 2 GO:0002544 chronic inflammatory response 2/445 18/18722 0.0671304682947559 0.258208533077874 S100A9/S100A8 2 GO:0006595 polyamine metabolic process 2/445 18/18722 0.0671304682947559 0.258208533077874 SAT1/AMD1 2 GO:0007549 dosage compensation 2/445 18/18722 0.0671304682947559 0.258208533077874 CDYL/YTHDC1 2 GO:0030730 sequestering of triglyceride 2/445 18/18722 0.0671304682947559 0.258208533077874 PLIN2/PPARG 2 GO:0030889 negative regulation of B cell proliferation 2/445 18/18722 0.0671304682947559 0.258208533077874 TYROBP/PAWR 2 GO:0034433 steroid esterification 2/445 18/18722 0.0671304682947559 0.258208533077874 APOE/APOC1 2 GO:0034434 sterol esterification 2/445 18/18722 0.0671304682947559 0.258208533077874 APOE/APOC1 2 GO:0034435 cholesterol esterification 2/445 18/18722 0.0671304682947559 0.258208533077874 APOE/APOC1 2 GO:0036499 PERK-mediated unfolded protein response 2/445 18/18722 0.0671304682947559 0.258208533077874 PPP1R15A/ATF4 2 GO:0042790 nucleolar large rRNA transcription by RNA polymerase I 2/445 18/18722 0.0671304682947559 0.258208533077874 NCL/SMARCB1 2 GO:0043116 negative regulation of vascular permeability 2/445 18/18722 0.0671304682947559 0.258208533077874 FERMT2/AKAP12 2 GO:0045953 negative regulation of natural killer cell mediated cytotoxicity 2/445 18/18722 0.0671304682947559 0.258208533077874 HLA-B/HLA-A 2 GO:0048268 clathrin coat assembly 2/445 18/18722 0.0671304682947559 0.258208533077874 CLTB/CLINT1 2 GO:0071800 podosome assembly 2/445 18/18722 0.0671304682947559 0.258208533077874 GSN/RHOA 2 GO:1903209 positive regulation of oxidative stress-induced cell death 2/445 18/18722 0.0671304682947559 0.258208533077874 PAWR/MCL1 2 GO:1990840 response to lectin 2/445 18/18722 0.0671304682947559 0.258208533077874 TYROBP/PAK2 2 GO:1990858 cellular response to lectin 2/445 18/18722 0.0671304682947559 0.258208533077874 TYROBP/PAK2 2 GO:2000136 regulation of cell proliferation involved in heart morphogenesis 2/445 18/18722 0.0671304682947559 0.258208533077874 CTNNB1/PIM1 2 GO:0061008 hepaticobiliary system development 7/445 150/18722 0.0672942153105971 0.258357252275164 CEBPB/ANXA1/HMOX1/SRSF5/RPS15/RB1CC1/PIK3CA 7 GO:0070665 positive regulation of leukocyte proliferation 7/445 150/18722 0.0672942153105971 0.258357252275164 CD74/ANXA1/SLC7A1/HLA-DPA1/HLA-A/HLA-DPB1/AIF1 7 GO:0045766 positive regulation of angiogenesis 8/445 181/18722 0.0678608002458058 0.260049133409484 KLF4/HMOX1/RHOB/SASH1/ANGPTL4/TJP1/JAK1/PDCD6 8 GO:1904018 positive regulation of vasculature development 8/445 181/18722 0.0678608002458058 0.260049133409484 KLF4/HMOX1/RHOB/SASH1/ANGPTL4/TJP1/JAK1/PDCD6 8 GO:1903312 negative regulation of mRNA metabolic process 5/445 92/18722 0.0682538131706186 0.261312791666196 SFSWAP/SRSF4/PKP3/YBX1/SRSF9 5 GO:0017148 negative regulation of translation 10/445 245/18722 0.0686054405397507 0.262415810064546 NCL/EIF2AK2/MEX3D/EIF2AK4/YBX1/EIF4A3/LSM14A/CALR/HNRNPR/ATF4 10 GO:0015909 long-chain fatty acid transport 4/445 65/18722 0.0687757078497825 0.26258082174441 APOE/PLIN2/ANXA1/PPARG 4 GO:0071677 positive regulation of mononuclear cell migration 4/445 65/18722 0.0687757078497825 0.26258082174441 WNK1/AIF1/CALR/RHOA 4 GO:0055069 zinc ion homeostasis 3/445 40/18722 0.0690475130537075 0.263132173823677 S100A9/S100A8/MT2A 3 GO:1901223 negative regulation of NIK/NF-kappaB signaling 3/445 40/18722 0.0690475130537075 0.263132173823677 TMSB4X/LITAF/CPNE1 3 GO:0031349 positive regulation of defense response 11/445 278/18722 0.0691355943115627 0.263225013918033 CEBPB/TYROBP/S100A9/S100A8/RIOK3/PAK2/RPS19/PLSCR1/LSM14A/VAMP8/NFKBIZ 11 GO:0044409 entry into host 7/445 151/18722 0.0692014636457529 0.263233191823762 CD74/HLA-DRB1/GSN/CBL/HSPA1B/PLSCR1/VAMP8 7 GO:0051346 negative regulation of hydrolase activity 14/445 379/18722 0.0698120211639435 0.265311370219182 APOC1/KLF4/PPP1R15A/SPINT1/ANXA1/TNFAIP8/PAK2/WNK1/CST6/ANGPTL4/BIRC7/SERPINF1/CST3/RDX 14 GO:0003007 heart morphogenesis 10/445 246/18722 0.0700804512731533 0.266086713427754 TPM1/CTNNB1/PIM1/ADAMTS1/SOX4/PKP2/LRP2/FHL2/DSP/GATA3 10 GO:0090398 cellular senescence 5/445 93/18722 0.0707972846438021 0.268069278518374 ING2/PAWR/YBX1/PLK2/CALR 5 GO:1901796 regulation of signal transduction by p53 class mediator 5/445 93/18722 0.0707972846438021 0.268069278518374 CD74/ING2/TRIM24/RPS15/RPL23 5 GO:1902807 negative regulation of cell cycle G1/S phase transition 5/445 93/18722 0.0707972846438021 0.268069278518374 KLF4/SOX4/PLK2/BRD7/WEE1 5 GO:0031109 microtubule polymerization or depolymerization 6/445 122/18722 0.0711327284937538 0.268877033166626 CCSAP/KIF2A/CENPJ/GOLGA2/HSPA1B/MAP7D3 6 GO:0016573 histone acetylation 7/445 152/18722 0.0711407884897415 0.268877033166626 TAF7/IWS1/SMARCB1/PHF14/MORF4L2/BRD7/GATA3 7 GO:0050678 regulation of epithelial cell proliferation 14/445 381/18722 0.0721872671103567 0.272582815752179 APOE/OSR2/WNT7A/SFRP1/CTNNB1/HMOX1/HMGN1/SERPINF1/PPARG/RGCC/SPARC/TCF7L2/GATA3/PDCD6 14 GO:0050856 regulation of T cell receptor signaling pathway 3/445 41/18722 0.0732403249624958 0.273975834754326 PAWR/GBP1/LAPTM5 3 GO:0007249 I-kappaB kinase/NF-kappaB signaling 11/445 281/18722 0.0733435619030706 0.273975834754326 CD74/CTNNB1/HLA-DRB1/UBE2V1/HMOX1/LITAF/GSTP1/RIOK3/CPNE1/PLK2/RHOA 11 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity 5/445 94/18722 0.0733922949872219 0.273975834754326 CCNL1/CCNG2/CDC37/RGCC/CCNI 5 GO:0002042 cell migration involved in sprouting angiogenesis 5/445 94/18722 0.0733922949872219 0.273975834754326 KLF4/ANXA1/HMOX1/PLK2/RHOA 5 GO:1990830 cellular response to leukemia inhibitory factor 5/445 94/18722 0.0733922949872219 0.273975834754326 KLF4/UBXN2A/NCL/CTBP2/KLF5 5 GO:0002523 leukocyte migration involved in inflammatory response 2/445 19/18722 0.0738826143588281 0.273975834754326 S100A9/S100A8 2 GO:0002716 negative regulation of natural killer cell mediated immunity 2/445 19/18722 0.0738826143588281 0.273975834754326 HLA-B/HLA-A 2 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 2/445 19/18722 0.0738826143588281 0.273975834754326 SOX4/PLK2 2 GO:0008356 asymmetric cell division 2/445 19/18722 0.0738826143588281 0.273975834754326 ING2/GOLGA2 2 GO:0035313 wound healing, spreading of epidermal cells 2/445 19/18722 0.0738826143588281 0.273975834754326 WNT7A/FERMT2 2 GO:0045603 positive regulation of endothelial cell differentiation 2/445 19/18722 0.0738826143588281 0.273975834754326 CTNNB1/VEZF1 2 GO:0045780 positive regulation of bone resorption 2/445 19/18722 0.0738826143588281 0.273975834754326 CA2/SPP1 2 GO:0045947 negative regulation of translational initiation 2/445 19/18722 0.0738826143588281 0.273975834754326 EIF2AK4/ATF4 2 GO:0051444 negative regulation of ubiquitin-protein transferase activity 2/445 19/18722 0.0738826143588281 0.273975834754326 RPS15/RPL23 2 GO:0051571 positive regulation of histone H3-K4 methylation 2/445 19/18722 0.0738826143588281 0.273975834754326 CTNNB1/RTF1 2 GO:0060065 uterus development 2/445 19/18722 0.0738826143588281 0.273975834754326 WNT7A/GATA3 2 GO:0061323 cell proliferation involved in heart morphogenesis 2/445 19/18722 0.0738826143588281 0.273975834754326 CTNNB1/PIM1 2 GO:0070262 peptidyl-serine dephosphorylation 2/445 19/18722 0.0738826143588281 0.273975834754326 PPP1R15A/PPP2R2D 2 GO:1903204 negative regulation of oxidative stress-induced neuron death 2/445 19/18722 0.0738826143588281 0.273975834754326 CTNNB1/ATF4 2 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation 2/445 19/18722 0.0738826143588281 0.273975834754326 IRF1/HLA-A 2 GO:0018105 peptidyl-serine phosphorylation 12/445 315/18722 0.0743198441124197 0.275350023343862 PNCK/MORC3/HAX1/MAPKAP1/SH2D3A/SMG1/PAK2/WNK1/HSP90AB1/PLK2/PIK3CA/PLCL2 12 GO:0007369 gastrulation 8/445 185/18722 0.0749344618633673 0.277272347507997 KLF4/MYADM/SFRP1/CTNNB1/WNK1/ETS2/DUSP4/RTF1 8 GO:0006879 cellular iron ion homeostasis 4/445 67/18722 0.0751071790998422 0.277272347507997 FTL/SRI/HMOX1/SLC40A1 4 GO:0043967 histone H4 acetylation 4/445 67/18722 0.0751071790998422 0.277272347507997 TAF7/IWS1/SMARCB1/MORF4L2 4 GO:0061077 chaperone-mediated protein folding 4/445 67/18722 0.0751071790998422 0.277272347507997 CD74/ERO1A/HSPA2/HSPA1B 4 GO:0030516 regulation of axon extension 5/445 95/18722 0.07603861982907 0.279960373007031 APOE/SEMA4C/SHTN1/GOLGA4/MACF1 5 GO:0036473 cell death in response to oxidative stress 5/445 95/18722 0.07603861982907 0.279960373007031 PAGE4/CTNNB1/PAWR/MCL1/ATF4 5 GO:1990823 response to leukemia inhibitory factor 5/445 95/18722 0.07603861982907 0.279960373007031 KLF4/UBXN2A/NCL/CTBP2/KLF5 5 GO:0051146 striated muscle cell differentiation 11/445 283/18722 0.0762375690558187 0.280442918761876 KRT19/TPM1/KRT8/CSRP1/TMOD3/YBX1/MORF4L2/KLF5/MYOF/CALR/FHL2 11 GO:0008217 regulation of blood pressure 8/445 186/18722 0.0767698753576886 0.281398717926009 TPM1/TAC3/HMOX1/WNK1/NAV2/PPARG/HBB/RHOA 8 GO:0031345 negative regulation of cell projection organization 8/445 186/18722 0.0767698753576886 0.281398717926009 APOE/VIM/SPP1/SEMA4C/RTN4RL2/ODF2L/MAP4/RHOA 8 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 8/445 186/18722 0.0767698753576886 0.281398717926009 CD74/CTNNB1/HLA-DRB1/UBE2V1/HMOX1/LITAF/PLK2/RHOA 8 GO:0071478 cellular response to radiation 8/445 186/18722 0.0767698753576886 0.281398717926009 SFRP1/RHOB/EIF2AK4/NET1/ADIRF/GRB2/ATF4/GATA3 8 GO:0050803 regulation of synapse structure or activity 9/445 218/18722 0.0769522905845171 0.281735878120885 APOE/WNT7A/TANC2/ZMYND8/YWHAZ/UBE2V2/SRGN/RHOA/SPARC 9 GO:0030574 collagen catabolic process 3/445 42/18722 0.077543861879314 0.281735878120885 MRC2/CST3/CTSS 3 GO:0033003 regulation of mast cell activation 3/445 42/18722 0.077543861879314 0.281735878120885 HMOX1/PLSCR1/VAMP8 3 GO:0033574 response to testosterone 3/445 42/18722 0.077543861879314 0.281735878120885 SPP1/CBL/CALR 3 GO:0045292 mRNA cis splicing, via spliceosome 3/445 42/18722 0.077543861879314 0.281735878120885 SFSWAP/RBM17/PRPF40A 3 GO:0045773 positive regulation of axon extension 3/445 42/18722 0.077543861879314 0.281735878120885 SHTN1/GOLGA4/MACF1 3 GO:0046596 regulation of viral entry into host cell 3/445 42/18722 0.077543861879314 0.281735878120885 CD74/HLA-DRB1/GSN 3 GO:0060999 positive regulation of dendritic spine development 3/445 42/18722 0.077543861879314 0.281735878120885 APOE/ZMYND8/MAPK6 3 GO:0072595 maintenance of protein localization in organelle 3/445 42/18722 0.077543861879314 0.281735878120885 MORC3/TAF3/SP100 3 GO:2000404 regulation of T cell migration 3/445 42/18722 0.077543861879314 0.281735878120885 WNK1/AIF1/RHOA 3 GO:0072659 protein localization to plasma membrane 11/445 284/18722 0.0777112695336227 0.282096005662034 MYADM/GOPC/PKP3/GOLGA4/PKP2/MACF1/RAB8B/RDX/GBP1/GOLPH3/VAMP8 11 GO:0034394 protein localization to cell surface 4/445 68/18722 0.0783795222884742 0.284022637345339 CTNNB1/TYROBP/GOPC/HSP90AB1 4 GO:1904888 cranial skeletal system development 4/445 68/18722 0.0783795222884742 0.284022637345339 MTHFD1L/CTNNB1/EIF4A3/TMEM107 4 GO:0061136 regulation of proteasomal protein catabolic process 8/445 187/18722 0.078632101387746 0.284316827666331 APOE/GABARAP/RYBP/TMF1/UBE2V2/HSP90AB1/HSPA1B/PLK2 8 GO:0001823 mesonephros development 5/445 96/18722 0.0787360084362825 0.284316827666331 OSR2/SFRP1/CTNNB1/BASP1/GATA3 5 GO:0010769 regulation of cell morphogenesis involved in differentiation 5/445 96/18722 0.0787360084362825 0.284316827666331 MYADM/FERMT2/LIMS1/CALR/GBP1 5 GO:0030510 regulation of BMP signaling pathway 5/445 96/18722 0.0787360084362825 0.284316827666331 SKIL/SFRP1/UBE2D1/LRP2/PPARG 5 GO:0009267 cellular response to starvation 7/445 156/18722 0.079218701560207 0.285810005367 SFRP1/GABARAP/EIF2AK2/JUN/EIF2AK4/HNRNPA1/ATF4 7 GO:0031929 TOR signaling 6/445 126/18722 0.0802925467509463 0.287149123894125 MAPKAP1/SMG1/PIK3CA/GOLPH3/GATA3/PDCD6 6 GO:0032874 positive regulation of stress-activated MAPK cascade 6/445 126/18722 0.0802925467509463 0.287149123894125 STK3/WNT7A/SEMA4C/EIF2AK2/SASH1/RB1CC1 6 GO:0048705 skeletal system morphogenesis 9/445 220/18722 0.0803946736548559 0.287149123894125 MTHFD1L/OSR2/WNT7A/SFRP1/FBN2/CTNNB1/ANKRD11/EIF4A3/TMEM107 9 GO:0001906 cell killing 8/445 188/18722 0.0805211341400162 0.287149123894125 HLA-B/LYZ/HLA-DRA/HLA-DRB1/TYROBP/HLA-A/HSP90AB1/RPS19 8 GO:0001832 blastocyst growth 2/445 20/18722 0.0808410629602682 0.287149123894125 SBDS/RTF1 2 GO:0003215 cardiac right ventricle morphogenesis 2/445 20/18722 0.0808410629602682 0.287149123894125 SOX4/GATA3 2 GO:0006590 thyroid hormone generation 2/445 20/18722 0.0808410629602682 0.287149123894125 CGA/GATA3 2 GO:0006896 Golgi to vacuole transport 2/445 20/18722 0.0808410629602682 0.287149123894125 AP3S1/LAPTM5 2 GO:0032495 response to muramyl dipeptide 2/445 20/18722 0.0808410629602682 0.287149123894125 VIM/CHMP5 2 GO:0032930 positive regulation of superoxide anion generation 2/445 20/18722 0.0808410629602682 0.287149123894125 TYROBP/GSTP1 2 GO:0032986 protein-DNA complex disassembly 2/445 20/18722 0.0808410629602682 0.287149123894125 SMARCB1/RPL23 2 GO:0034104 negative regulation of tissue remodeling 2/445 20/18722 0.0808410629602682 0.287149123894125 SFRP1/CST3 2 GO:0051004 regulation of lipoprotein lipase activity 2/445 20/18722 0.0808410629602682 0.287149123894125 APOC1/ANGPTL4 2 GO:0071379 cellular response to prostaglandin stimulus 2/445 20/18722 0.0808410629602682 0.287149123894125 SFRP1/GNB1 2 GO:0072567 chemokine (C-X-C motif) ligand 2 production 2/445 20/18722 0.0808410629602682 0.287149123894125 KLF4/CD74 2 GO:2000010 positive regulation of protein localization to cell surface 2/445 20/18722 0.0808410629602682 0.287149123894125 TYROBP/HSP90AB1 2 GO:2000341 regulation of chemokine (C-X-C motif) ligand 2 production 2/445 20/18722 0.0808410629602682 0.287149123894125 KLF4/CD74 2 GO:2000678 negative regulation of transcription regulatory region DNA binding 2/445 20/18722 0.0808410629602682 0.287149123894125 TMSB4X/SRI 2 GO:0009895 negative regulation of catabolic process 12/445 320/18722 0.0813070431596138 0.288348072086522 APOC1/RYBP/HMOX1/PKP3/RPL23/GOLGA2/SMG1/YBX1/HSP90AB1/MCL1/CST3/PIK3CA 12 GO:0002262 myeloid cell homeostasis 7/445 157/18722 0.0813182047883802 0.288348072086522 ANXA1/INHA/HMOX1/TMOD3/RPS19/HSPA1B/GATA3 7 GO:0007004 telomere maintenance via telomerase 4/445 69/18722 0.0817219645624591 0.28911939552175 CTNNB1/HSP90AB1/HNRNPA1/CCT6A 4 GO:0033344 cholesterol efflux 4/445 69/18722 0.0817219645624591 0.28911939552175 APOE/APOC1/RXRA/PPARG 4 GO:0009268 response to pH 3/445 43/18722 0.0819556553270321 0.28911939552175 CA2/SERPINF1/CTSS 3 GO:0098815 modulation of excitatory postsynaptic potential 3/445 43/18722 0.0819556553270321 0.28911939552175 WNT7A/ZMYND8/EIF4A3 3 GO:1904591 positive regulation of protein import 3/445 43/18722 0.0819556553270321 0.28911939552175 ARHGEF5/NUTF2/HSP90AB1 3 GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand 3/445 43/18722 0.0819556553270321 0.28911939552175 HSPA1B/MCL1/CTNNA1 3 GO:0018393 internal peptidyl-lysine acetylation 7/445 158/18722 0.0834496306601371 0.294138587250023 TAF7/IWS1/SMARCB1/PHF14/MORF4L2/BRD7/GATA3 7 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 13/445 356/18722 0.0840826256336394 0.296117072883686 CD74/HLA-B/HLA-DRA/HLA-DRB1/ANXA1/FCER1G/HLA-DPA1/HLA-A/C1QB/HLA-DPB1/C1QA/GATA3/NFKBIZ 13 GO:0001952 regulation of cell-matrix adhesion 6/445 128/18722 0.0851088286999652 0.298482455011428 PLEKHA2/SFRP1/FERMT2/LIMS1/MACF1/RHOA 6 GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 6/445 128/18722 0.0851088286999652 0.298482455011428 STK3/WNT7A/SEMA4C/EIF2AK2/SASH1/RB1CC1 6 GO:0002381 immunoglobulin production involved in immunoglobulin-mediated immune response 4/445 70/18722 0.0851337210187877 0.298482455011428 HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1 4 GO:0060415 muscle tissue morphogenesis 4/445 70/18722 0.0851337210187877 0.298482455011428 TPM1/PKP2/LRP2/DSP 4 GO:0070830 bicellular tight junction assembly 4/445 70/18722 0.0851337210187877 0.298482455011428 CLDN7/PAK2/TJP1/CLDN19 4 GO:0050808 synapse organization 15/445 426/18722 0.0851878030642638 0.298482455011428 APOE/WNT7A/CTNNB1/TANC2/ZMYND8/NDRG1/YWHAZ/PPFIBP1/CTBP2/UBE2V2/C1QB/C1QA/SRGN/RHOA/SPARC 15 GO:0032200 telomere organization 7/445 159/18722 0.0856129176975592 0.299463982225755 GNL3/CTNNB1/SP100/SMG1/HSP90AB1/HNRNPA1/CCT6A 7 GO:0051170 import into nucleus 7/445 159/18722 0.0856129176975592 0.299463982225755 NUTF2/NUP58/HTATIP2/RPL23/HSP90AB1/HNRNPA1/TXNIP 7 GO:0021762 substantia nigra development 3/445 44/18722 0.0864731697335321 0.301961677235183 MAPKAP1/BASP1/RHOA 3 GO:0089718 amino acid import across plasma membrane 3/445 44/18722 0.0864731697335321 0.301961677235183 SLC7A1/SLC1A6/SLC7A5 3 GO:0071375 cellular response to peptide hormone stimulus 11/445 290/18722 0.0869285177782824 0.302661081355687 CA2/AP3S1/RAP1B/GSTP1/SRSF5/GRB2/PIK3CA/PPARG/RAB8B/CSH1/ZNF106 11 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage 5/445 99/18722 0.0871316653828193 0.302661081355687 CD74/SKIL/ING2/HMOX1/MCL1 5 GO:0034101 erythrocyte homeostasis 6/445 129/18722 0.087575604930089 0.302661081355687 INHA/HMOX1/TMOD3/RPS19/HSPA1B/GATA3 6 GO:0006475 internal protein amino acid acetylation 7/445 160/18722 0.0878079943578816 0.302661081355687 TAF7/IWS1/SMARCB1/PHF14/MORF4L2/BRD7/GATA3 7 GO:0032516 positive regulation of phosphoprotein phosphatase activity 2/445 21/18722 0.087992243696001 0.302661081355687 PPP1R15A/HSP90AB1 2 GO:0045056 transcytosis 2/445 21/18722 0.087992243696001 0.302661081355687 LRP2/FCGRT 2 GO:0046599 regulation of centriole replication 2/445 21/18722 0.087992243696001 0.302661081355687 CENPJ/PLK2 2 GO:0048199 vesicle targeting, to, from or within Golgi 2/445 21/18722 0.087992243696001 0.302661081355687 ARFGAP3/PDCD6 2 GO:0051767 nitric-oxide synthase biosynthetic process 2/445 21/18722 0.087992243696001 0.302661081355687 GSTP1/AKAP12 2 GO:0051769 regulation of nitric-oxide synthase biosynthetic process 2/445 21/18722 0.087992243696001 0.302661081355687 GSTP1/AKAP12 2 GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response 2/445 21/18722 0.087992243696001 0.302661081355687 CD74/LAPTM5 2 GO:0071498 cellular response to fluid shear stress 2/445 21/18722 0.087992243696001 0.302661081355687 KLF4/CA2 2 GO:0097062 dendritic spine maintenance 2/445 21/18722 0.087992243696001 0.302661081355687 APOE/ZMYND8 2 GO:0150146 cell junction disassembly 2/445 21/18722 0.087992243696001 0.302661081355687 C1QB/C1QA 2 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 2/445 21/18722 0.087992243696001 0.302661081355687 CD74/ING2 2 GO:1903427 negative regulation of reactive oxygen species biosynthetic process 2/445 21/18722 0.087992243696001 0.302661081355687 PAGE4/RHOA 2 GO:2000047 regulation of cell-cell adhesion mediated by cadherin 2/445 21/18722 0.087992243696001 0.302661081355687 TJP1/RGCC 2 GO:2000178 negative regulation of neural precursor cell proliferation 2/445 21/18722 0.087992243696001 0.302661081355687 SPINT1/CTNNA1 2 GO:0051052 regulation of DNA metabolic process 13/445 359/18722 0.0883237433742035 0.303548572278565 KLF4/GNL3/CTNNB1/UBE2V1/SMG1/UBE2V2/HSP90AB1/MBD2/HNRNPA1/PIK3CA/CCT6A/RGCC/GATA3 13 GO:0060485 mesenchyme development 11/445 291/18722 0.0885273539799169 0.303995427507096 SFRP1/CTNNB1/SEMA4C/FERMT2/BASP1/HNRNPAB/WWTR1/RGCC/TCF7L2/GATA3/PDCD6 11 GO:0032722 positive regulation of chemokine production 4/445 71/18722 0.088613964646644 0.304040106275155 CD74/HMOX1/EIF2AK2/AIF1 4 GO:0006364 rRNA processing 9/445 225/18722 0.08940326084652 0.306493668512012 MPHOSPH10/ZNHIT6/RIOK3/RPS15/SBDS/RBFA/EIF4A3/RPS19/RPS28 9 GO:0060840 artery development 5/445 100/18722 0.090030293422381 0.307796252869584 APOE/LUZP1/SOX4/LRP2/HPGD 5 GO:0015918 sterol transport 6/445 130/18722 0.0900812562864505 0.307796252869584 APOE/APOC1/LIMA1/RXRA/OSBPL1A/PPARG 6 GO:0042476 odontogenesis 6/445 130/18722 0.0900812562864505 0.307796252869584 OSR2/CA2/CTNNB1/ANKRD11/CTNNA1/RHOA 6 GO:0043467 regulation of generation of precursor metabolites and energy 6/445 130/18722 0.0900812562864505 0.307796252869584 PHLDA2/BNIP3/IFNAR1/PIK3CA/RHOA/NDUFA4 6 GO:0007565 female pregnancy 8/445 193/18722 0.0903676993988693 0.308519806790685 FOS/TAC3/SPP1/FOSB/PSG11/HPGD/CALR/RPL29 8 GO:0045927 positive regulation of growth 10/445 259/18722 0.0910815694118471 0.3099740762018 SFRP1/S100A9/PIM1/S100A8/SHTN1/GOLGA4/BASP1/MACF1/CSH1/RHOA 10 GO:0010824 regulation of centrosome duplication 3/445 45/18722 0.0910938098545111 0.3099740762018 CENPJ/CHMP5/PLK2 3 GO:0048538 thymus development 3/445 45/18722 0.0910938098545111 0.3099740762018 CTNNB1/LMO4/GATA3 3 GO:0071364 cellular response to epidermal growth factor stimulus 3/445 45/18722 0.0910938098545111 0.3099740762018 NCL/GSTP1/CBL 3 GO:0032729 positive regulation of interferon-gamma production 4/445 72/18722 0.0921618281809221 0.312835260653565 HLA-DPA1/HLA-A/HLA-DPB1/SLC7A5 4 GO:0035567 non-canonical Wnt signaling pathway 4/445 72/18722 0.0921618281809221 0.312835260653565 WNT7A/SFRP1/RNF213/RHOA 4 GO:0050709 negative regulation of protein secretion 4/445 72/18722 0.0921618281809221 0.312835260653565 APOE/SFRP1/ANXA1/RAB11FIP1 4 GO:0018022 peptidyl-lysine methylation 6/445 131/18722 0.0926256029212887 0.313636365301511 CTNNB1/IWS1/SMARCB1/KMT2C/RTF1/GATA3 6 GO:0019079 viral genome replication 6/445 131/18722 0.0926256029212887 0.313636365301511 SMARCB1/EIF2AK2/CTBP2/EIF2AK4/MX1/PLSCR1 6 GO:0045089 positive regulation of innate immune response 6/445 131/18722 0.0926256029212887 0.313636365301511 TYROBP/RIOK3/PAK2/RPS19/PLSCR1/LSM14A 6 GO:0046777 protein autophosphorylation 9/445 227/18722 0.093167523283649 0.315212971895785 PIM1/CLK4/EIF2AK2/HTATIP2/TRIM24/SMG1/PAK2/EIF2AK4/WNK1 9 GO:0030111 regulation of Wnt signaling pathway 12/445 328/18722 0.0933217975187083 0.315476551186403 APOE/STK3/SFRP1/RNF213/RPS12/SOX4/WNK1/MBD2/PLPP3/MACF1/WWTR1/TCF7L2 12 GO:0031589 cell-substrate adhesion 13/445 363/18722 0.0941834051616282 0.317564335684945 PLEKHA2/MYADM/SFRP1/CTNNB1/FERMT2/LIMS1/CD63/COL17A1/CCDC80/MACF1/CALR/GBP1/RHOA 13 GO:0002089 lens morphogenesis in camera-type eye 2/445 22/18722 0.0953231121397561 0.317564335684945 CTNNB1/ATF4 2 GO:0002220 innate immune response activating cell surface receptor signaling pathway 2/445 22/18722 0.0953231121397561 0.317564335684945 TYROBP/PAK2 2 GO:0002320 lymphoid progenitor cell differentiation 2/445 22/18722 0.0953231121397561 0.317564335684945 SOX4/GATA3 2 GO:0007398 ectoderm development 2/445 22/18722 0.0953231121397561 0.317564335684945 CTNNB1/ETS2 2 GO:0034755 iron ion transmembrane transport 2/445 22/18722 0.0953231121397561 0.317564335684945 SLC25A37/SLC40A1 2 GO:0035357 peroxisome proliferator activated receptor signaling pathway 2/445 22/18722 0.0953231121397561 0.317564335684945 RXRA/PPARG 2 GO:0035561 regulation of chromatin binding 2/445 22/18722 0.0953231121397561 0.317564335684945 CTBP2/MBD2 2 GO:0036120 cellular response to platelet-derived growth factor stimulus 2/445 22/18722 0.0953231121397561 0.317564335684945 CBL/RDX 2 GO:0045061 thymic T cell selection 2/445 22/18722 0.0953231121397561 0.317564335684945 CD74/GATA3 2 GO:0045624 positive regulation of T-helper cell differentiation 2/445 22/18722 0.0953231121397561 0.317564335684945 ANXA1/NFKBIZ 2 GO:0048026 positive regulation of mRNA splicing, via spliceosome 2/445 22/18722 0.0953231121397561 0.317564335684945 NCL/RBM3 2 GO:0051412 response to corticosterone 2/445 22/18722 0.0953231121397561 0.317564335684945 FOS/FOSB 2 GO:0060563 neuroepithelial cell differentiation 2/445 22/18722 0.0953231121397561 0.317564335684945 CEBPB/SOX4 2 GO:0060713 labyrinthine layer morphogenesis 2/445 22/18722 0.0953231121397561 0.317564335684945 SPINT1/GRB2 2 GO:0071404 cellular response to low-density lipoprotein particle stimulus 2/445 22/18722 0.0953231121397561 0.317564335684945 FCER1G/PPARG 2 GO:1900120 regulation of receptor binding 2/445 22/18722 0.0953231121397561 0.317564335684945 PHLDA2/PLCL2 2 GO:2000773 negative regulation of cellular senescence 2/445 22/18722 0.0953231121397561 0.317564335684945 YBX1/PLK2 2 GO:0042274 ribosomal small subunit biogenesis 4/445 73/18722 0.0957764059412578 0.318176420264008 RIOK3/RPS15/RPS19/RPS28 4 GO:0034198 cellular response to amino acid starvation 3/445 46/18722 0.0958149278161283 0.318176420264008 EIF2AK2/EIF2AK4/ATF4 3 GO:0042398 cellular modified amino acid biosynthetic process 3/445 46/18722 0.0958149278161283 0.318176420264008 MTHFD1L/PLSCR1/PLOD2 3 GO:1900271 regulation of long-term synaptic potentiation 3/445 46/18722 0.0958149278161283 0.318176420264008 APOE/TYROBP/EIF2AK4 3 GO:0035710 CD4-positive, alpha-beta T cell activation 5/445 102/18722 0.0959754535886034 0.318453492991583 HLA-DRA/HLA-DRB1/ANXA1/GATA3/NFKBIZ 5 GO:0043393 regulation of protein binding 8/445 196/18722 0.0965954078026814 0.3202533143121 APOE/STK3/PHLDA2/GOLGA2/HSP90AB1/PLK2/PLCL2/TCF7L2 8 GO:0050680 negative regulation of epithelial cell proliferation 7/445 164/18722 0.0969044185946559 0.320506127473598 APOE/SFRP1/SERPINF1/PPARG/RGCC/SPARC/GATA3 7 GO:0050792 regulation of viral process 7/445 164/18722 0.0969044185946559 0.320506127473598 CD74/HLA-DRB1/EIF2AK2/GSN/MX1/PLSCR1/RSF1 7 GO:2001242 regulation of intrinsic apoptotic signaling pathway 7/445 164/18722 0.0969044185946559 0.320506127473598 CD74/SKIL/ING2/S100A9/S100A8/MCL1/DNAJA1 7 GO:0006997 nucleus organization 6/445 133/18722 0.0978295899133696 0.323307228745704 ANKLE2/UBXN2A/TMF1/CHMP5/RPS19/SERBP1 6 GO:0048732 gland development 15/445 436/18722 0.098587166131116 0.325550426289081 CGA/CEBPB/SFRP1/CTNNB1/ANXA1/HMOX1/SRSF5/RPS15/RB1CC1/SERPINF1/PIK3CA/LMO4/LBH/GATA3/PSAP 15 GO:0003279 cardiac septum development 5/445 103/18722 0.0990211687948684 0.326076077466341 LUZP1/SOX4/LRP2/LMO4/GATA3 5 GO:0090277 positive regulation of peptide hormone secretion 5/445 103/18722 0.0990211687948684 0.326076077466341 HLA-DRB1/SRI/SOX4/RAB8B/TCF7L2 5 GO:0071772 response to BMP 7/445 165/18722 0.0992570236809167 0.326076077466341 SKIL/SFRP1/SPINT1/UBE2D1/LRP2/PPARG/GATA3 7 GO:0071773 cellular response to BMP stimulus 7/445 165/18722 0.0992570236809167 0.326076077466341 SKIL/SFRP1/SPINT1/UBE2D1/LRP2/PPARG/GATA3 7 GO:0030968 endoplasmic reticulum unfolded protein response 4/445 74/18722 0.0994567556542216 0.326076077466341 PPP1R15A/ERO1A/EIF2AK2/ATF4 4 GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway 4/445 74/18722 0.0994567556542216 0.326076077466341 SFRP1/CALR/LBH/RHOA 4 GO:0046470 phosphatidylcholine metabolic process 4/445 74/18722 0.0994567556542216 0.326076077466341 APOC1/LPCAT1/GDPD3/DBI 4 GO:0048844 artery morphogenesis 4/445 74/18722 0.0994567556542216 0.326076077466341 APOE/SOX4/LRP2/HPGD 4 GO:0120192 tight junction assembly 4/445 74/18722 0.0994567556542216 0.326076077466341 CLDN7/PAK2/TJP1/CLDN19 4 GO:0050673 epithelial cell proliferation 15/445 437/18722 0.099995189441701 0.327547867722147 APOE/OSR2/WNT7A/CEBPB/SFRP1/CTNNB1/HMOX1/HMGN1/SERPINF1/PPARG/RGCC/SPARC/TCF7L2/GATA3/PDCD6 15 GO:0032868 response to insulin 10/445 264/18722 0.10006424813976 0.327547867722147 AP3S1/GSTP1/SRSF4/SRSF5/GRB2/PIK3CA/PPARG/RAB8B/GGH/ZNF106 10 GO:0002705 positive regulation of leukocyte mediated immunity 6/445 134/18722 0.100488798541219 0.327595233155442 HLA-B/HLA-DRA/HLA-DRB1/TYROBP/HLA-A/GATA3 6 GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 6/445 134/18722 0.100488798541219 0.327595233155442 GABARAP/RYBP/UBE2V2/HSP90AB1/HSPA1B/PLK2 6 GO:0001774 microglial cell activation 3/445 47/18722 0.100633829792848 0.327595233155442 TYROBP/C1QA/AIF1 3 GO:0010712 regulation of collagen metabolic process 3/445 47/18722 0.100633829792848 0.327595233155442 VIM/CST3/RGCC 3 GO:0045581 negative regulation of T cell differentiation 3/445 47/18722 0.100633829792848 0.327595233155442 CD74/ANXA1/IRF1 3 GO:0046677 response to antibiotic 3/445 47/18722 0.100633829792848 0.327595233155442 RPL23/CBL/JAK1 3 GO:0051972 regulation of telomerase activity 3/445 47/18722 0.100633829792848 0.327595233155442 KLF4/CTNNB1/HSP90AB1 3 GO:0045732 positive regulation of protein catabolic process 9/445 231/18722 0.100970550153158 0.328432553293461 APOE/LPCAT1/GABARAP/LRP2/UBE2V2/HSPA1B/PLK2/RDX/LAPTM5 9 GO:0030307 positive regulation of cell growth 7/445 166/18722 0.101640782477818 0.330092824226311 SFRP1/S100A9/S100A8/SHTN1/GOLGA4/MACF1/RHOA 7 GO:0061013 regulation of mRNA catabolic process 7/445 166/18722 0.101640782477818 0.330092824226311 VIM/PKP3/MEX3D/HNRNPM/YBX1/SERBP1/HNRNPR 7 GO:0032963 collagen metabolic process 5/445 104/18722 0.102115059440773 0.330805372867501 VIM/MRC2/CST3/CTSS/RGCC 5 GO:0048661 positive regulation of smooth muscle cell proliferation 5/445 104/18722 0.102115059440773 0.330805372867501 HMOX1/JUN/ADAMTS1/AIF1/HPGD 5 GO:0002758 innate immune response-activating signal transduction 2/445 23/18722 0.102821132597887 0.330805372867501 TYROBP/PAK2 2 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules 2/445 23/18722 0.102821132597887 0.330805372867501 CLDN7/CLDN19 2 GO:0034695 response to prostaglandin E 2/445 23/18722 0.102821132597887 0.330805372867501 SFRP1/GNB1 2 GO:0035640 exploration behavior 2/445 23/18722 0.102821132597887 0.330805372867501 APOE/EIF4A3 2 GO:0036119 response to platelet-derived growth factor 2/445 23/18722 0.102821132597887 0.330805372867501 CBL/RDX 2 GO:0042026 protein refolding 2/445 23/18722 0.102821132597887 0.330805372867501 HSPA2/HSPA1B 2 GO:0045723 positive regulation of fatty acid biosynthetic process 2/445 23/18722 0.102821132597887 0.330805372867501 CD74/ANXA1 2 GO:1902410 mitotic cytokinetic process 2/445 23/18722 0.102821132597887 0.330805372867501 CHMP5/RHOA 2 GO:1903306 negative regulation of regulated secretory pathway 2/445 23/18722 0.102821132597887 0.330805372867501 RAP1B/HMOX1 2 GO:1904666 regulation of ubiquitin protein ligase activity 2/445 23/18722 0.102821132597887 0.330805372867501 RPS15/RPL23 2 GO:0006278 RNA-dependent DNA biosynthetic process 4/445 75/18722 0.103201900256498 0.331772023314859 CTNNB1/HSP90AB1/HNRNPA1/CCT6A 4 GO:1903034 regulation of response to wounding 7/445 167/18722 0.104055555446284 0.334256220488803 APOE/KLF4/SPP1/ANXA1/FERMT2/PLPP3/CLDN19 7 GO:0002443 leukocyte mediated immunity 15/445 440/18722 0.104293614701141 0.334760623411354 CD74/HLA-B/HLA-DRA/HLA-DRB1/TYROBP/HMOX1/FCER1G/HLA-DPA1/HLA-A/C1QB/CBL/HLA-DPB1/C1QA/GATA3/VAMP8 15 GO:0007160 cell-matrix adhesion 9/445 233/18722 0.105008613239829 0.33679392957588 PLEKHA2/SFRP1/CTNNB1/FERMT2/LIMS1/CD63/COL17A1/MACF1/RHOA 9 GO:0002791 regulation of peptide secretion 8/445 200/18722 0.105268717699274 0.337214144491162 CD74/SFRP1/HLA-DRB1/SRI/S100A8/SOX4/RAB8B/TCF7L2 8 GO:0043303 mast cell degranulation 3/445 48/18722 0.105547782335287 0.337214144491162 HMOX1/CBL/VAMP8 3 GO:1903053 regulation of extracellular matrix organization 3/445 48/18722 0.105547782335287 0.337214144491162 CST3/IER3IP1/RGCC 3 GO:1905710 positive regulation of membrane permeability 3/445 48/18722 0.105547782335287 0.337214144491162 BNIP3/BNIP3L/LAPTM5 3 GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process 3/445 48/18722 0.105547782335287 0.337214144491162 RYBP/RPL23/HSP90AB1 3 GO:0072073 kidney epithelium development 6/445 136/18722 0.105920462222709 0.338143299414226 SFRP1/CTNNB1/BASP1/IRX2/WWTR1/GATA3 6 GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 7/445 168/18722 0.106501193742449 0.33973469602321 HLA-B/HLA-DRA/HLA-DRB1/ANXA1/HLA-A/GATA3/NFKBIZ 7 GO:0001937 negative regulation of endothelial cell proliferation 4/445 76/18722 0.107010829677062 0.340309266663544 APOE/PPARG/RGCC/SPARC 4 GO:0006809 nitric oxide biosynthetic process 4/445 76/18722 0.107010829677062 0.340309266663544 KLF4/HSP90AB1/AIF1/HBB 4 GO:0043536 positive regulation of blood vessel endothelial cell migration 4/445 76/18722 0.107010829677062 0.340309266663544 TMSB4X/ANXA1/HMOX1/PLK2 4 GO:0071426 ribonucleoprotein complex export from nucleus 4/445 76/18722 0.107010829677062 0.340309266663544 IWS1/RPS15/SMG1/YTHDC1 4 GO:0051056 regulation of small GTPase mediated signal transduction 11/445 302/18722 0.107294945787906 0.340950323884492 APOE/ARHGEF5/VAV2/GABARAP/MAPKAP1/ARHGAP29/ARHGAP21/CHN2/NET1/CBL/RDX 11 GO:0006473 protein acetylation 8/445 201/18722 0.107502514369251 0.34108516655866 TAF7/IWS1/SMARCB1/SOX4/PHF14/MORF4L2/BRD7/GATA3 8 GO:0051054 positive regulation of DNA metabolic process 8/445 201/18722 0.107502514369251 0.34108516655866 KLF4/GNL3/CTNNB1/UBE2V2/HSP90AB1/HNRNPA1/CCT6A/RGCC 8 GO:0001824 blastocyst development 5/445 106/18722 0.108445496158184 0.34312445518769 KLF4/SKIL/SMARCB1/SBDS/RTF1 5 GO:0042116 macrophage activation 5/445 106/18722 0.108445496158184 0.34312445518769 JUND/CD74/TYROBP/C1QA/AIF1 5 GO:0010977 negative regulation of neuron projection development 6/445 137/18722 0.108692402972856 0.34312445518769 APOE/VIM/SPP1/SEMA4C/RTN4RL2/RHOA 6 GO:0050714 positive regulation of protein secretion 6/445 137/18722 0.108692402972856 0.34312445518769 HLA-DRB1/SRI/SOX4/IER3IP1/GOLPH3/TCF7L2 6 GO:0031214 biomineral tissue development 7/445 169/18722 0.108977539333203 0.34312445518769 OSR2/CEBPB/FBN2/SPP1/SBDS/SRGN/ATF4 7 GO:0001702 gastrulation with mouth forming second 2/445 24/18722 0.110474261384851 0.34312445518769 CTNNB1/ETS2 2 GO:0001911 negative regulation of leukocyte mediated cytotoxicity 2/445 24/18722 0.110474261384851 0.34312445518769 HLA-B/HLA-A 2 GO:0002726 positive regulation of T cell cytokine production 2/445 24/18722 0.110474261384851 0.34312445518769 HLA-A/GATA3 2 GO:0010155 regulation of proton transport 2/445 24/18722 0.110474261384851 0.34312445518769 TMSB4X/NDUFA4 2 GO:0010288 response to lead ion 2/445 24/18722 0.110474261384851 0.34312445518769 PLSCR1/SPARC 2 GO:0032928 regulation of superoxide anion generation 2/445 24/18722 0.110474261384851 0.34312445518769 TYROBP/GSTP1 2 GO:0036003 positive regulation of transcription from RNA polymerase II promoter in response to stress 2/445 24/18722 0.110474261384851 0.34312445518769 CEBPB/ATF4 2 GO:0038095 Fc-epsilon receptor signaling pathway 2/445 24/18722 0.110474261384851 0.34312445518769 VAV2/FCER1G 2 GO:0060479 lung cell differentiation 2/445 24/18722 0.110474261384851 0.34312445518769 CTNNB1/THRB 2 GO:0060571 morphogenesis of an epithelial fold 2/445 24/18722 0.110474261384851 0.34312445518769 LUZP1/CTNNB1 2 GO:0070841 inclusion body assembly 2/445 24/18722 0.110474261384851 0.34312445518769 HSPA2/HSPA1B 2 GO:1903077 negative regulation of protein localization to plasma membrane 2/445 24/18722 0.110474261384851 0.34312445518769 GOPC/GBP1 2 GO:2000209 regulation of anoikis 2/445 24/18722 0.110474261384851 0.34312445518769 MCL1/PIK3CA 2 GO:0002279 mast cell activation involved in immune response 3/445 49/18722 0.110554018362337 0.34312445518769 HMOX1/CBL/VAMP8 3 GO:0002762 negative regulation of myeloid leukocyte differentiation 3/445 49/18722 0.110554018362337 0.34312445518769 SFRP1/CTNNB1/INHA 3 GO:0042304 regulation of fatty acid biosynthetic process 3/445 49/18722 0.110554018362337 0.34312445518769 APOC1/CD74/ANXA1 3 GO:0046605 regulation of centrosome cycle 3/445 49/18722 0.110554018362337 0.34312445518769 CENPJ/CHMP5/PLK2 3 GO:0052372 modulation by symbiont of entry into host 3/445 49/18722 0.110554018362337 0.34312445518769 CD74/HLA-DRB1/GSN 3 GO:0070169 positive regulation of biomineral tissue development 3/445 49/18722 0.110554018362337 0.34312445518769 OSR2/CEBPB/FBN2 3 GO:0070849 response to epidermal growth factor 3/445 49/18722 0.110554018362337 0.34312445518769 NCL/GSTP1/CBL 3 GO:0072091 regulation of stem cell proliferation 3/445 49/18722 0.110554018362337 0.34312445518769 PIM1/EIF2AK2/FERMT2 3 GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation 3/445 49/18722 0.110554018362337 0.34312445518769 JUN/ADAMTS1/HPGD 3 GO:1904752 regulation of vascular associated smooth muscle cell migration 3/445 49/18722 0.110554018362337 0.34312445518769 TPM1/ADAMTS1/RHOA 3 GO:1990928 response to amino acid starvation 3/445 49/18722 0.110554018362337 0.34312445518769 EIF2AK2/EIF2AK4/ATF4 3 GO:0031016 pancreas development 4/445 77/18722 0.11088250259652 0.343370028655341 CTNNB1/ANXA1/SOX4/TCF7L2 4 GO:0048644 muscle organ morphogenesis 4/445 77/18722 0.11088250259652 0.343370028655341 TPM1/PKP2/LRP2/DSP 4 GO:0071166 ribonucleoprotein complex localization 4/445 77/18722 0.11088250259652 0.343370028655341 IWS1/RPS15/SMG1/YTHDC1 4 GO:0016072 rRNA metabolic process 9/445 236/18722 0.111235098524506 0.344203889142124 MPHOSPH10/ZNHIT6/RIOK3/RPS15/SBDS/RBFA/EIF4A3/RPS19/RPS28 9 GO:0035107 appendage morphogenesis 6/445 138/18722 0.111501384739167 0.344254275304559 OSR2/WNT7A/FBN2/CTNNB1/SOX4/TMEM107 6 GO:0035108 limb morphogenesis 6/445 138/18722 0.111501384739167 0.344254275304559 OSR2/WNT7A/FBN2/CTNNB1/SOX4/TMEM107 6 GO:1903322 positive regulation of protein modification by small protein conjugation or removal 6/445 138/18722 0.111501384739167 0.344254275304559 GNL3/GABARAP/UBE2D1/BIRC7/LAPTM5/PDCD6 6 GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process 5/445 107/18722 0.111681056047094 0.344551488073595 GABARAP/UBE2V2/HSPA1B/PLK2/LAPTM5 5 GO:0032869 cellular response to insulin stimulus 8/445 203/18722 0.112047978130163 0.345167932629159 AP3S1/GSTP1/SRSF5/GRB2/PIK3CA/PPARG/RAB8B/ZNF106 8 GO:0051701 biological process involved in interaction with host 8/445 203/18722 0.112047978130163 0.345167932629159 CD74/HLA-DRB1/GSN/RXRA/CBL/HSPA1B/PLSCR1/VAMP8 8 GO:0018108 peptidyl-tyrosine phosphorylation 13/445 375/18722 0.113167259961494 0.348356148212318 CD74/SFRP1/HAX1/SH3BP5/CLK4/EIF2AK2/PAK2/EFEMP1/PARP14/CBL/JAK1/CSH1/WEE1 13 GO:0110148 biomineralization 7/445 171/18722 0.114021675041217 0.350724899177414 OSR2/CEBPB/FBN2/SPP1/SBDS/SRGN/ATF4 7 GO:0032024 positive regulation of insulin secretion 4/445 78/18722 0.114815848181952 0.350770255239524 HLA-DRB1/SRI/SOX4/TCF7L2 4 GO:0032371 regulation of sterol transport 4/445 78/18722 0.114815848181952 0.350770255239524 APOE/APOC1/RXRA/PPARG 4 GO:0032374 regulation of cholesterol transport 4/445 78/18722 0.114815848181952 0.350770255239524 APOE/APOC1/RXRA/PPARG 4 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 4/445 78/18722 0.114815848181952 0.350770255239524 KLF4/TNFAIP8/PAK2/BIRC7 4 GO:0070373 negative regulation of ERK1 and ERK2 cascade 4/445 78/18722 0.114815848181952 0.350770255239524 KLF4/GSTP1/DUSP4/GBP1 4 GO:0018205 peptidyl-lysine modification 13/445 376/18722 0.114844016144376 0.350770255239524 GNL3/CTNNB1/TAF7/IWS1/SMARCB1/SOX4/PHF14/KMT2C/MORF4L2/PLOD2/RTF1/BRD7/GATA3 13 GO:0007173 epidermal growth factor receptor signaling pathway 5/445 108/18722 0.114962820260086 0.350770255239524 FAM83B/EFEMP1/CBL/GRB2/PIK3CA 5 GO:0033138 positive regulation of peptidyl-serine phosphorylation 5/445 108/18722 0.114962820260086 0.350770255239524 HAX1/MAPKAP1/SH2D3A/HSP90AB1/PIK3CA 5 GO:0048872 homeostasis of number of cells 10/445 272/18722 0.115474625905089 0.350770255239524 CD74/SKIL/ANXA1/INHA/HMOX1/TMOD3/SOX4/RPS19/HSPA1B/GATA3 10 GO:0051962 positive regulation of nervous system development 10/445 272/18722 0.115474625905089 0.350770255239524 SKIL/WNT7A/CTNNB1/SPINT1/SHTN1/GOLGA4/LRP2/UBE2V2/SERPINF1/MACF1 10 GO:0002448 mast cell mediated immunity 3/445 50/18722 0.115649742831332 0.350770255239524 HMOX1/CBL/VAMP8 3 GO:0007140 male meiotic nuclear division 3/445 50/18722 0.115649742831332 0.350770255239524 ING2/HSPA2/FOXJ3 3 GO:0018023 peptidyl-lysine trimethylation 3/445 50/18722 0.115649742831332 0.350770255239524 IWS1/SMARCB1/RTF1 3 GO:0019083 viral transcription 3/445 50/18722 0.115649742831332 0.350770255239524 SMARCB1/JUN/RSF1 3 GO:0030490 maturation of SSU-rRNA 3/445 50/18722 0.115649742831332 0.350770255239524 RIOK3/RPS19/RPS28 3 GO:0045058 T cell selection 3/445 50/18722 0.115649742831332 0.350770255239524 CD74/RHOA/GATA3 3 GO:0110151 positive regulation of biomineralization 3/445 50/18722 0.115649742831332 0.350770255239524 OSR2/CEBPB/FBN2 3 GO:1903747 regulation of establishment of protein localization to mitochondrion 3/445 50/18722 0.115649742831332 0.350770255239524 HAX1/BNIP3L/DNAJA1 3 GO:1904738 vascular associated smooth muscle cell migration 3/445 50/18722 0.115649742831332 0.350770255239524 TPM1/ADAMTS1/RHOA 3 GO:0010876 lipid localization 15/445 448/18722 0.116300479060523 0.352485164342642 APOE/APOC1/LIMA1/PLIN2/SPP1/ANXA1/RXRA/TMF1/OSBPL1A/PLSCR1/HILPDA/PPARG/DBI/NRIP1/PSAP 15 GO:0042770 signal transduction in response to DNA damage 7/445 172/18722 0.116589104241574 0.352583886985315 CD74/SP100/NDRG1/SOX4/EIF2AK4/PLK2/GRB2 7 GO:0048736 appendage development 7/445 172/18722 0.116589104241574 0.352583886985315 OSR2/WNT7A/FBN2/CTNNB1/FERMT2/SOX4/TMEM107 7 GO:0060173 limb development 7/445 172/18722 0.116589104241574 0.352583886985315 OSR2/WNT7A/FBN2/CTNNB1/FERMT2/SOX4/TMEM107 7 GO:0030177 positive regulation of Wnt signaling pathway 6/445 140/18722 0.117229299362364 0.353842877342064 SFRP1/RPS12/SOX4/WNK1/MBD2/MACF1 6 GO:0018212 peptidyl-tyrosine modification 13/445 378/18722 0.118240980894121 0.353842877342064 CD74/SFRP1/HAX1/SH3BP5/CLK4/EIF2AK2/PAK2/EFEMP1/PARP14/CBL/JAK1/CSH1/WEE1 13 GO:0010447 response to acidic pH 2/445 25/18722 0.118270930603471 0.353842877342064 SERPINF1/CTSS 2 GO:0031579 membrane raft organization 2/445 25/18722 0.118270930603471 0.353842877342064 MYADM/GSN 2 GO:0032331 negative regulation of chondrocyte differentiation 2/445 25/18722 0.118270930603471 0.353842877342064 CTNNB1/EFEMP1 2 GO:0033233 regulation of protein sumoylation 2/445 25/18722 0.118270930603471 0.353842877342064 GNL3/CTNNB1 2 GO:0033622 integrin activation 2/445 25/18722 0.118270930603471 0.353842877342064 RAP1B/FERMT2 2 GO:0072202 cell differentiation involved in metanephros development 2/445 25/18722 0.118270930603471 0.353842877342064 CTNNB1/WWTR1 2 GO:0086064 cell communication by electrical coupling involved in cardiac conduction 2/445 25/18722 0.118270930603471 0.353842877342064 SRI/PKP2 2 GO:1901798 positive regulation of signal transduction by p53 class mediator 2/445 25/18722 0.118270930603471 0.353842877342064 RPS15/RPL23 2 GO:1903055 positive regulation of extracellular matrix organization 2/445 25/18722 0.118270930603471 0.353842877342064 IER3IP1/RGCC 2 GO:1904753 negative regulation of vascular associated smooth muscle cell migration 2/445 25/18722 0.118270930603471 0.353842877342064 TPM1/RHOA 2 GO:0002456 T cell mediated immunity 5/445 109/18722 0.118290247787313 0.353842877342064 HLA-B/HLA-DRA/HLA-DRB1/HLA-A/GATA3 5 GO:0032414 positive regulation of ion transmembrane transporter activity 5/445 109/18722 0.118290247787313 0.353842877342064 TMSB4X/HSPA2/WNK1/CTSS/NDUFA4 5 GO:0072009 nephron epithelium development 5/445 109/18722 0.118290247787313 0.353842877342064 CTNNB1/BASP1/IRX2/WWTR1/GATA3 5 GO:0010770 positive regulation of cell morphogenesis involved in differentiation 4/445 79/18722 0.11880976779573 0.354882972352973 MYADM/FERMT2/LIMS1/CALR 4 GO:0050772 positive regulation of axonogenesis 4/445 79/18722 0.11880976779573 0.354882972352973 SKIL/SHTN1/GOLGA4/MACF1 4 GO:0017038 protein import 8/445 206/18722 0.119059121103648 0.355137827587763 APOE/ARHGEF5/NUTF2/NUP58/RPL23/HSP90AB1/TXNIP/RAB8B 8 GO:0001558 regulation of cell growth 14/445 414/18722 0.119067027646829 0.355137827587763 APOE/TSPYL2/SFRP1/SPP1/S100A9/SEMA4C/S100A8/SHTN1/GOLGA4/NET1/HSPA1B/MACF1/RHOA/CDA 14 GO:0016571 histone methylation 6/445 141/18722 0.120147615021652 0.358102307109988 CTNNB1/IWS1/SMARCB1/KMT2C/RTF1/GATA3 6 GO:0070372 regulation of ERK1 and ERK2 cascade 11/445 309/18722 0.120356520913464 0.358466321480549 APOE/KLF4/CD74/HLA-DRB1/RAP1B/GSTP1/FERMT2/YWHAZ/AKAP12/DUSP4/GBP1 11 GO:0009948 anterior/posterior axis specification 3/445 51/18722 0.120832138099524 0.358847996038197 CTNNB1/BASP1/ETS2 3 GO:0010874 regulation of cholesterol efflux 3/445 51/18722 0.120832138099524 0.358847996038197 APOE/RXRA/PPARG 3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling 3/445 51/18722 0.120832138099524 0.358847996038197 GSTP1/RIOK3/RHOA 3 GO:0046850 regulation of bone remodeling 3/445 51/18722 0.120832138099524 0.358847996038197 CA2/SFRP1/SPP1 3 GO:0016064 immunoglobulin mediated immune response 8/445 207/18722 0.121447115733289 0.360415255096419 CD74/HLA-DRA/HLA-DRB1/FCER1G/HLA-DPA1/C1QB/HLA-DPB1/C1QA 8 GO:0002698 negative regulation of immune effector process 5/445 110/18722 0.121662779586286 0.360796082175843 HLA-B/ANXA1/HMOX1/HLA-A/RPS19 5 GO:0048285 organelle fission 16/445 488/18722 0.122459141057377 0.362897210694422 ANKLE2/ING2/CCSAP/PPP2R2D/BNIP3/HSPA2/KIF2A/GOLGA2/FOXJ3/CHMP5/HSPA1B/LSM14A/CALR/PPARG/RGCC/RHOA 16 GO:0003012 muscle system process 15/445 452/18722 0.122599574668799 0.363052934019218 TPM1/KLF4/TNNI2/SRI/TPM3/HMOX1/TMOD3/GSN/PKP2/AIF1/CALD1/MYOF/PIK3CA/DSP/RHOA 15 GO:0120193 tight junction organization 4/445 80/18722 0.122863136676945 0.363572791986003 CLDN7/PAK2/TJP1/CLDN19 4 GO:0050729 positive regulation of inflammatory response 6/445 142/18722 0.123101737852454 0.364018095253035 CEBPB/S100A9/S100A8/RPS19/VAMP8/NFKBIZ 6 GO:0052126 movement in host environment 7/445 175/18722 0.124470489297833 0.367802282753468 CD74/HLA-DRB1/GSN/CBL/HSPA1B/PLSCR1/VAMP8 7 GO:0006936 muscle contraction 12/445 347/18722 0.125974834353294 0.369477203337008 TPM1/TNNI2/SRI/TPM3/TMOD3/GSN/PKP2/CALD1/MYOF/PIK3CA/DSP/RHOA 12 GO:0043090 amino acid import 3/445 52/18722 0.12609836898966 0.369477203337008 SLC7A1/SLC1A6/SLC7A5 3 GO:0060071 Wnt signaling pathway, planar cell polarity pathway 3/445 52/18722 0.12609836898966 0.369477203337008 WNT7A/SFRP1/RHOA 3 GO:2000378 negative regulation of reactive oxygen species metabolic process 3/445 52/18722 0.12609836898966 0.369477203337008 PAGE4/BNIP3/RHOA 3 GO:0002418 immune response to tumor cell 2/445 26/18722 0.126200032415521 0.369477203337008 HLA-DRB1/HLA-A 2 GO:0006706 steroid catabolic process 2/445 26/18722 0.126200032415521 0.369477203337008 APOE/SPP1 2 GO:0006760 folic acid-containing compound metabolic process 2/445 26/18722 0.126200032415521 0.369477203337008 MTHFD1L/GGH 2 GO:0032682 negative regulation of chemokine production 2/445 26/18722 0.126200032415521 0.369477203337008 KLF4/GSTP1 2 GO:0033598 mammary gland epithelial cell proliferation 2/445 26/18722 0.126200032415521 0.369477203337008 CEBPB/GATA3 2 GO:0060669 embryonic placenta morphogenesis 2/445 26/18722 0.126200032415521 0.369477203337008 SPINT1/GRB2 2 GO:0071425 hematopoietic stem cell proliferation 2/445 26/18722 0.126200032415521 0.369477203337008 PIM1/EIF2AK2 2 GO:1904376 negative regulation of protein localization to cell periphery 2/445 26/18722 0.126200032415521 0.369477203337008 GOPC/GBP1 2 GO:2000050 regulation of non-canonical Wnt signaling pathway 2/445 26/18722 0.126200032415521 0.369477203337008 SFRP1/RNF213 2 GO:0016358 dendrite development 9/445 243/18722 0.126543237704641 0.369957618512293 APOE/WNT7A/TANC2/ZMYND8/UBA6/PAK2/MAPK6/PLK2/RHOA 9 GO:0043543 protein acylation 9/445 243/18722 0.126543237704641 0.369957618512293 TAF7/IWS1/SMARCB1/SOX4/CDYL/PHF14/MORF4L2/BRD7/GATA3 9 GO:0010833 telomere maintenance via telomere lengthening 4/445 81/18722 0.126974805594192 0.370432854455937 CTNNB1/HSP90AB1/HNRNPA1/CCT6A 4 GO:0046209 nitric oxide metabolic process 4/445 81/18722 0.126974805594192 0.370432854455937 KLF4/HSP90AB1/AIF1/HBB 4 GO:0048708 astrocyte differentiation 4/445 81/18722 0.126974805594192 0.370432854455937 VIM/S100A9/S100A8/C1QA 4 GO:0006401 RNA catabolic process 10/445 278/18722 0.12785793864807 0.372746044146208 VIM/PKP3/MEX3D/SMG1/HNRNPM/YBX1/EIF4A3/HSPA1B/SERBP1/HNRNPR 10 GO:0045787 positive regulation of cell cycle 11/445 313/18722 0.128204786133961 0.373493632947386 ANXA1/HSPA2/TMOD3/ADAMTS1/CENPJ/AIF1/PLSCR1/CALR/RDX/RGCC/RHOA 11 GO:0002526 acute inflammatory response 5/445 112/18722 0.128540833464981 0.373961049986674 CEBPB/S100A8/GSTP1/PLSCR1/GATA3 5 GO:0002685 regulation of leukocyte migration 8/445 210/18722 0.128761974222303 0.373961049986674 CD74/ANXA1/HMOX1/MTUS1/WNK1/AIF1/CALR/RHOA 8 GO:0019724 B cell mediated immunity 8/445 210/18722 0.128761974222303 0.373961049986674 CD74/HLA-DRA/HLA-DRB1/FCER1G/HLA-DPA1/C1QB/HLA-DPB1/C1QA 8 GO:0042692 muscle cell differentiation 13/445 384/18722 0.128777362031 0.373961049986674 KRT19/TPM1/KRT8/CTNNB1/SEMA4C/CSRP1/TMOD3/YBX1/MORF4L2/KLF5/MYOF/CALR/FHL2 13 GO:0006898 receptor-mediated endocytosis 9/445 244/18722 0.128817858661592 0.373961049986674 APOE/APOC1/CLTB/FCER1G/LRP2/HSPG2/CBL/CD63/GRB2 9 GO:0033135 regulation of peptidyl-serine phosphorylation 6/445 144/18722 0.129116039261296 0.374300602237482 HAX1/MAPKAP1/SH2D3A/HSP90AB1/PIK3CA/PLCL2 6 GO:0046718 viral entry into host cell 6/445 144/18722 0.129116039261296 0.374300602237482 CD74/HLA-DRB1/GSN/HSPA1B/PLSCR1/VAMP8 6 GO:0045786 negative regulation of cell cycle 13/445 385/18722 0.130583446123648 0.378289071484426 KLF4/TSPYL2/CTNNB1/INHA/RHOB/SOX4/EIF2AK4/PLK2/HPGD/BRD7/RGCC/WEE1/GATA3 13 GO:0046889 positive regulation of lipid biosynthetic process 4/445 82/18722 0.131143602468607 0.378662288884153 APOE/CD74/CGA/ANXA1 4 GO:2001057 reactive nitrogen species metabolic process 4/445 82/18722 0.131143602468607 0.378662288884153 KLF4/HSP90AB1/AIF1/HBB 4 GO:2001252 positive regulation of chromosome organization 4/445 82/18722 0.131143602468607 0.378662288884153 GNL3/CTNNB1/HNRNPA1/CCT6A 4 GO:0001541 ovarian follicle development 3/445 53/18722 0.131445587571986 0.378662288884153 CEBPB/INHA/CTNNA1 3 GO:0007566 embryo implantation 3/445 53/18722 0.131445587571986 0.378662288884153 SPP1/CALR/RPL29 3 GO:0032210 regulation of telomere maintenance via telomerase 3/445 53/18722 0.131445587571986 0.378662288884153 CTNNB1/HNRNPA1/CCT6A 3 GO:0034381 plasma lipoprotein particle clearance 3/445 53/18722 0.131445587571986 0.378662288884153 APOE/APOC1/HMOX1 3 GO:1903202 negative regulation of oxidative stress-induced cell death 3/445 53/18722 0.131445587571986 0.378662288884153 PAGE4/CTNNB1/ATF4 3 GO:0002708 positive regulation of lymphocyte mediated immunity 5/445 113/18722 0.13204515299585 0.380124409077252 HLA-B/HLA-DRA/HLA-DRB1/HLA-A/GATA3 5 GO:0061351 neural precursor cell proliferation 6/445 145/18722 0.132175506542784 0.380234691872033 WNT7A/CTNNB1/SPINT1/LRP2/CTNNA1/RHOA 6 GO:0045861 negative regulation of proteolysis 12/445 351/18722 0.133576907285526 0.383998750171542 KLF4/SPINT1/RYBP/RPL23/TNFAIP8/PAK2/DNAJC1/HSP90AB1/CST6/BIRC7/SERPINF1/CST3 12 GO:0032786 positive regulation of DNA-templated transcription, elongation 2/445 27/18722 0.134250903788561 0.384065431821708 CTNNB1/HMGN1 2 GO:0032967 positive regulation of collagen biosynthetic process 2/445 27/18722 0.134250903788561 0.384065431821708 VIM/RGCC 2 GO:0034377 plasma lipoprotein particle assembly 2/445 27/18722 0.134250903788561 0.384065431821708 APOE/APOC1 2 GO:0036037 CD8-positive, alpha-beta T cell activation 2/445 27/18722 0.134250903788561 0.384065431821708 IRF1/HLA-A 2 GO:0042403 thyroid hormone metabolic process 2/445 27/18722 0.134250903788561 0.384065431821708 CGA/GATA3 2 GO:0098901 regulation of cardiac muscle cell action potential 2/445 27/18722 0.134250903788561 0.384065431821708 PKP2/DSP 2 GO:1903319 positive regulation of protein maturation 2/445 27/18722 0.134250903788561 0.384065431821708 GSN/SOX4 2 GO:0046785 microtubule polymerization 4/445 83/18722 0.135368333966157 0.386517741254257 CENPJ/GOLGA2/HSPA1B/MAP7D3 4 GO:0050672 negative regulation of lymphocyte proliferation 4/445 83/18722 0.135368333966157 0.386517741254257 CEBPB/HLA-DRB1/TYROBP/PAWR 4 GO:0006941 striated muscle contraction 7/445 179/18722 0.135388809391167 0.386517741254257 TPM1/TNNI2/SRI/GSN/PKP2/PIK3CA/DSP 7 GO:0002244 hematopoietic progenitor cell differentiation 5/445 114/18722 0.135592172966886 0.38683098517003 SFRP1/EIF2AK2/SBDS/SOX4/GATA3 5 GO:0001706 endoderm formation 3/445 54/18722 0.13687093767455 0.389940581747287 CTNNB1/DUSP4/RTF1 3 GO:0030520 intracellular estrogen receptor signaling pathway 3/445 54/18722 0.13687093767455 0.389940581747287 TAF7/SAFB/LBH 3 GO:0031346 positive regulation of cell projection organization 12/445 353/18722 0.137470740822523 0.391379483347927 APOE/SKIL/CDC42EP3/S100A9/ZMYND8/SHTN1/GOLGA4/UBE2V2/SERPINF1/MACF1/PIK3CA/RAB8B 12 GO:0007033 vacuole organization 7/445 180/18722 0.13819000392853 0.393156271507408 ATG12/UBXN2A/GABARAP/CHMP5/RB1CC1/TMEM165/LAPTM5 7 GO:0009953 dorsal/ventral pattern formation 4/445 84/18722 0.13964778705831 0.396444881478666 WNT7A/SFRP1/CTNNB1/AIDA 4 GO:0032945 negative regulation of mononuclear cell proliferation 4/445 84/18722 0.13964778705831 0.396444881478666 CEBPB/HLA-DRB1/TYROBP/PAWR 4 GO:0097061 dendritic spine organization 4/445 84/18722 0.13964778705831 0.396444881478666 APOE/WNT7A/TANC2/ZMYND8 4 GO:0051656 establishment of organelle localization 13/445 390/18722 0.139825754614964 0.396444881478666 AP3S1/CTNNB1/TANC2/HMOX1/ARHGAP21/RPS15/YWHAZ/CHMP5/ARFGAP3/CBL/MAP4/VAMP8/PDCD6 13 GO:1901987 regulation of cell cycle phase transition 13/445 390/18722 0.139825754614964 0.396444881478666 KLF4/ANXA1/HSPA2/TMOD3/ADAMTS1/SOX4/EIF2AK4/PLK2/AIF1/BRD7/RDX/RGCC/WEE1 13 GO:1904951 positive regulation of establishment of protein localization 11/445 319/18722 0.14049156937076 0.397846616702225 ARHGEF5/HLA-DRB1/NUTF2/SRI/CENPJ/SOX4/HSP90AB1/IER3IP1/CCT6A/GOLPH3/TCF7L2 11 GO:0045926 negative regulation of growth 9/445 249/18722 0.140512760534628 0.397846616702225 TSPYL2/STK3/CGA/SFRP1/SPP1/SEMA4C/MT2A/HSPA1B/CDA 9 GO:1903900 regulation of viral life cycle 6/445 148/18722 0.141558677997768 0.40048290718506 CD74/HLA-DRB1/EIF2AK2/GSN/MX1/PLSCR1 6 GO:0006516 glycoprotein catabolic process 2/445 28/18722 0.142413311705363 0.40048290718506 MAN1A1/CST3 2 GO:0010714 positive regulation of collagen metabolic process 2/445 28/18722 0.142413311705363 0.40048290718506 VIM/RGCC 2 GO:0010884 positive regulation of lipid storage 2/445 28/18722 0.142413311705363 0.40048290718506 PLIN2/HILPDA 2 GO:0019098 reproductive behavior 2/445 28/18722 0.142413311705363 0.40048290718506 THRB/MBD2 2 GO:0032801 receptor catabolic process 2/445 28/18722 0.142413311705363 0.40048290718506 APOE/LAPTM5 2 GO:0038094 Fc-gamma receptor signaling pathway 2/445 28/18722 0.142413311705363 0.40048290718506 VAV2/FCER1G 2 GO:0044331 cell-cell adhesion mediated by cadherin 2/445 28/18722 0.142413311705363 0.40048290718506 TJP1/RGCC 2 GO:0045671 negative regulation of osteoclast differentiation 2/445 28/18722 0.142413311705363 0.40048290718506 SFRP1/CTNNB1 2 GO:0090344 negative regulation of cell aging 2/445 28/18722 0.142413311705363 0.40048290718506 YBX1/PLK2 2 GO:0030326 embryonic limb morphogenesis 5/445 116/18722 0.142811741152524 0.401057309789992 OSR2/WNT7A/FBN2/CTNNB1/TMEM107 5 GO:0035113 embryonic appendage morphogenesis 5/445 116/18722 0.142811741152524 0.401057309789992 OSR2/WNT7A/FBN2/CTNNB1/TMEM107 5 GO:0003015 heart process 9/445 251/18722 0.145338499615529 0.40787591162483 TPM1/TNNI2/SRI/GSN/THRB/PKP2/PIK3CA/WWTR1/DSP 9 GO:0002702 positive regulation of production of molecular mediator of immune response 5/445 117/18722 0.146482967856031 0.410529945870599 CD74/HLA-A/SLC7A5/LAPTM5/GATA3 5 GO:0030301 cholesterol transport 5/445 117/18722 0.146482967856031 0.410529945870599 APOE/APOC1/LIMA1/RXRA/PPARG 5 GO:0007596 blood coagulation 8/445 217/18722 0.146689362258178 0.410829664737989 APOE/VAV2/CSRP1/FCER1G/PLSCR1/PIK3CA/HBB/F5 8 GO:0140014 mitotic nuclear division 10/445 287/18722 0.14772106371595 0.411568126293209 ANKLE2/CCSAP/PPP2R2D/KIF2A/GOLGA2/CHMP5/HSPA1B/LSM14A/RGCC/RHOA 10 GO:0002886 regulation of myeloid leukocyte mediated immunity 3/445 56/18722 0.147944591792728 0.411568126293209 TYROBP/HMOX1/VAMP8 3 GO:0030166 proteoglycan biosynthetic process 3/445 56/18722 0.147944591792728 0.411568126293209 CTNNB1/HS6ST1/TCF7L2 3 GO:0045071 negative regulation of viral genome replication 3/445 56/18722 0.147944591792728 0.411568126293209 EIF2AK2/MX1/PLSCR1 3 GO:0045599 negative regulation of fat cell differentiation 3/445 56/18722 0.147944591792728 0.411568126293209 FERMT2/WWTR1/GATA3 3 GO:0070534 protein K63-linked ubiquitination 3/445 56/18722 0.147944591792728 0.411568126293209 UBE2V1/UBE2V2/SASH1 3 GO:0071385 cellular response to glucocorticoid stimulus 3/445 56/18722 0.147944591792728 0.411568126293209 ANXA1/GSTP1/SERPINF1 3 GO:0090175 regulation of establishment of planar polarity 3/445 56/18722 0.147944591792728 0.411568126293209 WNT7A/SFRP1/RHOA 3 GO:0098781 ncRNA transcription 3/445 56/18722 0.147944591792728 0.411568126293209 POLR2L/NCL/SMARCB1 3 GO:0033674 positive regulation of kinase activity 15/445 467/18722 0.147949326445271 0.411568126293209 CD74/STK3/ARHGEF5/HLA-DRB1/VAV2/FERMT2/PAK2/WNK1/SASH1/HSP90AB1/PIK3CA/LMO4/RPLP1/RGCC/RHOA 15 GO:0015908 fatty acid transport 4/445 86/18722 0.148365916576347 0.411618268218192 APOE/PLIN2/ANXA1/PPARG 4 GO:0034103 regulation of tissue remodeling 4/445 86/18722 0.148365916576347 0.411618268218192 CA2/SFRP1/SPP1/CST3 4 GO:0060761 negative regulation of response to cytokine stimulus 4/445 86/18722 0.148365916576347 0.411618268218192 KLF4/GSTP1/PARP14/PPARG 4 GO:2000117 negative regulation of cysteine-type endopeptidase activity 4/445 86/18722 0.148365916576347 0.411618268218192 KLF4/TNFAIP8/PAK2/BIRC7 4 GO:0055001 muscle cell development 7/445 184/18722 0.149673505058158 0.41496566651748 KRT19/TPM1/KRT8/CSRP1/TMOD3/MYOF/FHL2 7 GO:0007613 memory 5/445 118/18722 0.150194253227075 0.41496566651748 APOE/CEBPB/EIF2AK4/PLK2/SERPINF1 5 GO:0002862 negative regulation of inflammatory response to antigenic stimulus 2/445 29/18722 0.150677438822614 0.41496566651748 HLA-DRB1/PLK2 2 GO:0010458 exit from mitosis 2/445 29/18722 0.150677438822614 0.41496566651748 PPP2R2D/RGCC 2 GO:0021522 spinal cord motor neuron differentiation 2/445 29/18722 0.150677438822614 0.41496566651748 SOX4/LMO4 2 GO:0034311 diol metabolic process 2/445 29/18722 0.150677438822614 0.41496566651748 PTS/PLPP3 2 GO:0048679 regulation of axon regeneration 2/445 29/18722 0.150677438822614 0.41496566651748 KLF4/SPP1 2 GO:0070198 protein localization to chromosome, telomeric region 2/445 29/18722 0.150677438822614 0.41496566651748 GNL3/CCT6A 2 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage 2/445 29/18722 0.150677438822614 0.41496566651748 CD74/ING2 2 GO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator 2/445 29/18722 0.150677438822614 0.41496566651748 CD74/ING2 2 GO:1903902 positive regulation of viral life cycle 2/445 29/18722 0.150677438822614 0.41496566651748 CD74/HLA-DRB1 2 GO:0048592 eye morphogenesis 6/445 151/18722 0.151240647421867 0.415962126830713 FBN2/CTNNB1/THRB/HMGN1/EFEMP1/ATF4 6 GO:0071333 cellular response to glucose stimulus 6/445 151/18722 0.151240647421867 0.415962126830713 HLA-DRB1/SRI/SMARCB1/SOX4/SERPINF1/PIK3CA 6 GO:0002011 morphogenesis of an epithelial sheet 3/445 57/18722 0.153587179268494 0.421014358034604 WNT7A/FERMT2/RHOA 3 GO:0010257 NADH dehydrogenase complex assembly 3/445 57/18722 0.153587179268494 0.421014358034604 NDUFB2/NDUFA3/NDUFB1 3 GO:0010883 regulation of lipid storage 3/445 57/18722 0.153587179268494 0.421014358034604 PLIN2/HILPDA/PPARG 3 GO:0032981 mitochondrial respiratory chain complex I assembly 3/445 57/18722 0.153587179268494 0.421014358034604 NDUFB2/NDUFA3/NDUFB1 3 GO:0061756 leukocyte adhesion to vascular endothelial cell 3/445 57/18722 0.153587179268494 0.421014358034604 KLF4/RHOA/GOLPH3 3 GO:0030282 bone mineralization 5/445 119/18722 0.153944904342757 0.421435652644087 OSR2/FBN2/SBDS/SRGN/ATF4 5 GO:0031398 positive regulation of protein ubiquitination 5/445 119/18722 0.153944904342757 0.421435652644087 GABARAP/UBE2D1/BIRC7/LAPTM5/PDCD6 5 GO:0044706 multi-multicellular organism process 8/445 220/18722 0.154729044017064 0.423021628613164 FOS/TAC3/SPP1/FOSB/PSG11/HPGD/CALR/RPL29 8 GO:0097529 myeloid leukocyte migration 8/445 220/18722 0.154729044017064 0.423021628613164 CD74/S100A9/ANXA1/S100A8/FCER1G/MTUS1/RPS19/AIF1 8 GO:0007611 learning or memory 9/445 255/18722 0.155237104113524 0.42411855724981 FOS/APOE/CEBPB/JUN/UBA6/EIF2AK4/EIF4A3/PLK2/SERPINF1 9 GO:0006869 lipid transport 13/445 398/18722 0.155335603272564 0.42411855724981 APOE/APOC1/LIMA1/PLIN2/SPP1/ANXA1/RXRA/TMF1/OSBPL1A/PLSCR1/PPARG/DBI/PSAP 13 GO:0120032 regulation of plasma membrane bounded cell projection assembly 7/445 186/18722 0.155578600684497 0.424501452726326 CDC42EP3/ZMYND8/ODF2L/MAP4/KLF5/PIK3CA/RDX 7 GO:0030218 erythrocyte differentiation 5/445 120/18722 0.157734216524513 0.42939144782817 INHA/TMOD3/RPS19/HSPA1B/GATA3 5 GO:0007517 muscle organ development 11/445 327/18722 0.157808513435558 0.42939144782817 FOS/TPM1/IGSF8/CTNNB1/SRI/BASP1/PKP2/LRP2/KLF5/DSP/RHOA 11 GO:0071331 cellular response to hexose stimulus 6/445 153/18722 0.157855697237435 0.42939144782817 HLA-DRB1/SRI/SMARCB1/SOX4/SERPINF1/PIK3CA 6 GO:0031571 mitotic G1 DNA damage checkpoint signaling 2/445 30/18722 0.159033869565989 0.42939144782817 SOX4/PLK2 2 GO:0034368 protein-lipid complex remodeling 2/445 30/18722 0.159033869565989 0.42939144782817 APOE/APOC1 2 GO:0034369 plasma lipoprotein particle remodeling 2/445 30/18722 0.159033869565989 0.42939144782817 APOE/APOC1 2 GO:0034694 response to prostaglandin 2/445 30/18722 0.159033869565989 0.42939144782817 SFRP1/GNB1 2 GO:0043304 regulation of mast cell degranulation 2/445 30/18722 0.159033869565989 0.42939144782817 HMOX1/VAMP8 2 GO:0044030 regulation of DNA methylation 2/445 30/18722 0.159033869565989 0.42939144782817 MBD2/PIK3CA 2 GO:0044788 modulation by host of viral process 2/445 30/18722 0.159033869565989 0.42939144782817 APOE/EIF2AK4 2 GO:0045577 regulation of B cell differentiation 2/445 30/18722 0.159033869565989 0.42939144782817 SFRP1/INHA 2 GO:0046825 regulation of protein export from nucleus 2/445 30/18722 0.159033869565989 0.42939144782817 SP100/TCF7L2 2 GO:0048799 animal organ maturation 2/445 30/18722 0.159033869565989 0.42939144782817 RHOA/GATA3 2 GO:0060218 hematopoietic stem cell differentiation 2/445 30/18722 0.159033869565989 0.42939144782817 SFRP1/EIF2AK2 2 GO:0061384 heart trabecula morphogenesis 2/445 30/18722 0.159033869565989 0.42939144782817 ADAMTS1/FHL2 2 GO:0140058 neuron projection arborization 2/445 30/18722 0.159033869565989 0.42939144782817 LRP2/MACF1 2 GO:0006826 iron ion transport 3/445 58/18722 0.159296472480914 0.429538986826799 FTL/SLC25A37/SLC40A1 3 GO:0086065 cell communication involved in cardiac conduction 3/445 58/18722 0.159296472480914 0.429538986826799 SRI/PKP2/DSP 3 GO:0050767 regulation of neurogenesis 12/445 364/18722 0.159966907319836 0.431065423443081 SKIL/WNT7A/CTNNB1/SPINT1/SPP1/SEMA4C/SHTN1/GOLGA4/LRP2/SERPINF1/MACF1/CTNNA1 12 GO:0007599 hemostasis 8/445 222/18722 0.160203634914319 0.431140857218925 APOE/VAV2/CSRP1/FCER1G/PLSCR1/PIK3CA/HBB/F5 8 GO:0050817 coagulation 8/445 222/18722 0.160203634914319 0.431140857218925 APOE/VAV2/CSRP1/FCER1G/PLSCR1/PIK3CA/HBB/F5 8 GO:0030856 regulation of epithelial cell differentiation 6/445 154/18722 0.16121002314457 0.433177212965439 CEBPB/CTNNB1/GRHL1/VEZF1/WWTR1/GATA3 6 GO:0071326 cellular response to monosaccharide stimulus 6/445 154/18722 0.16121002314457 0.433177212965439 HLA-DRB1/SRI/SMARCB1/SOX4/SERPINF1/PIK3CA 6 GO:0001704 formation of primary germ layer 5/445 121/18722 0.161561473948357 0.433177212965439 KLF4/CTNNB1/ETS2/DUSP4/RTF1 5 GO:0038127 ERBB signaling pathway 5/445 121/18722 0.161561473948357 0.433177212965439 FAM83B/EFEMP1/CBL/GRB2/PIK3CA 5 GO:0006575 cellular modified amino acid metabolic process 7/445 188/18722 0.161589466274447 0.433177212965439 MTHFD1L/CGA/GSTP1/PLSCR1/PLOD2/GGH/GATA3 7 GO:0060491 regulation of cell projection assembly 7/445 188/18722 0.161589466274447 0.433177212965439 CDC42EP3/ZMYND8/ODF2L/MAP4/KLF5/PIK3CA/RDX 7 GO:0010657 muscle cell apoptotic process 4/445 89/18722 0.161822231589072 0.433519869451659 BNIP3/HMOX1/GNB1/PPARG 4 GO:0042593 glucose homeostasis 9/445 258/18722 0.162872394727024 0.436041808086228 HLA-DRB1/SRI/SMARCB1/SOX4/SERPINF1/PIK3CA/PPARG/TCF7L2/FAM3B 9 GO:0050920 regulation of chemotaxis 8/445 223/18722 0.162974715973163 0.436041808086228 CD74/TMSB4X/SEMA4C/GSTP1/MTUS1/WNK1/AIF1/CALR 8 GO:0000280 nuclear division 14/445 439/18722 0.16415369842706 0.438702184614477 ANKLE2/ING2/CCSAP/PPP2R2D/HSPA2/KIF2A/GOLGA2/FOXJ3/CHMP5/HSPA1B/LSM14A/CALR/RGCC/RHOA 14 GO:0048638 regulation of developmental growth 11/445 330/18722 0.1645692646173 0.438702184614477 APOE/STK3/CGA/SPP1/SEMA4C/PIM1/SHTN1/GOLGA4/BASP1/MACF1/PIK3CA 11 GO:0070371 ERK1 and ERK2 cascade 11/445 330/18722 0.1645692646173 0.438702184614477 APOE/KLF4/CD74/HLA-DRB1/RAP1B/GSTP1/FERMT2/YWHAZ/AKAP12/DUSP4/GBP1 11 GO:0006406 mRNA export from nucleus 3/445 59/18722 0.165069632970521 0.438702184614477 IWS1/SMG1/YTHDC1 3 GO:0051055 negative regulation of lipid biosynthetic process 3/445 59/18722 0.165069632970521 0.438702184614477 APOE/APOC1/LPCAT1 3 GO:0051353 positive regulation of oxidoreductase activity 3/445 59/18722 0.165069632970521 0.438702184614477 APOE/RFK/NDUFA4 3 GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus 3/445 59/18722 0.165069632970521 0.438702184614477 IWS1/SMG1/YTHDC1 3 GO:0090303 positive regulation of wound healing 3/445 59/18722 0.165069632970521 0.438702184614477 ANXA1/FERMT2/PLPP3 3 GO:2000351 regulation of endothelial cell apoptotic process 3/445 59/18722 0.165069632970521 0.438702184614477 ANGPTL4/RGCC/GATA3 3 GO:0002688 regulation of leukocyte chemotaxis 5/445 122/18722 0.165425950249835 0.438702184614477 CD74/MTUS1/WNK1/AIF1/CALR 5 GO:0019730 antimicrobial humoral response 5/445 122/18722 0.165425950249835 0.438702184614477 LYZ/RPL39/S100A9/HLA-A/RPS19 5 GO:0033500 carbohydrate homeostasis 9/445 259/18722 0.16545686443837 0.438702184614477 HLA-DRB1/SRI/SMARCB1/SOX4/SERPINF1/PIK3CA/PPARG/TCF7L2/FAM3B 9 GO:0060537 muscle tissue development 13/445 403/18722 0.165468913481526 0.438702184614477 FOS/TPM1/IGSF8/CTNNB1/PIM1/CSRP1/PKP2/LRP2/KLF5/CALR/FHL2/DSP/RHOA 13 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 4/445 90/18722 0.16640362610828 0.438702184614477 GABARAP/UBE2V2/HSPA1B/PLK2 4 GO:0035304 regulation of protein dephosphorylation 4/445 90/18722 0.16640362610828 0.438702184614477 ANKLE2/PPP1R15A/HSP90AB1/CAMTA1 4 GO:0042475 odontogenesis of dentin-containing tooth 4/445 90/18722 0.16640362610828 0.438702184614477 CA2/CTNNB1/ANKRD11/CTNNA1 4 GO:0046849 bone remodeling 4/445 90/18722 0.16640362610828 0.438702184614477 CA2/SFRP1/CTNNB1/SPP1 4 GO:0097581 lamellipodium organization 4/445 90/18722 0.16640362610828 0.438702184614477 VAV2/SNX2/PIK3CA/GOLPH3 4 GO:0071214 cellular response to abiotic stimulus 11/445 331/18722 0.166854380991333 0.438702184614477 SFRP1/BNIP3/RHOB/EIF2AK4/NET1/IRF1/ADIRF/GRB2/PIK3CA/ATF4/GATA3 11 GO:0104004 cellular response to environmental stimulus 11/445 331/18722 0.166854380991333 0.438702184614477 SFRP1/BNIP3/RHOB/EIF2AK4/NET1/IRF1/ADIRF/GRB2/PIK3CA/ATF4/GATA3 11 GO:0001516 prostaglandin biosynthetic process 2/445 31/18722 0.167473576649003 0.438702184614477 CD74/ANXA1 2 GO:0006301 postreplication repair 2/445 31/18722 0.167473576649003 0.438702184614477 UBE2V1/UBE2V2 2 GO:0033006 regulation of mast cell activation involved in immune response 2/445 31/18722 0.167473576649003 0.438702184614477 HMOX1/VAMP8 2 GO:0044819 mitotic G1/S transition checkpoint signaling 2/445 31/18722 0.167473576649003 0.438702184614477 SOX4/PLK2 2 GO:0046457 prostanoid biosynthetic process 2/445 31/18722 0.167473576649003 0.438702184614477 CD74/ANXA1 2 GO:0060390 regulation of SMAD protein signal transduction 2/445 31/18722 0.167473576649003 0.438702184614477 PPARG/WWTR1 2 GO:0061099 negative regulation of protein tyrosine kinase activity 2/445 31/18722 0.167473576649003 0.438702184614477 SH3BP5/CBL 2 GO:0065005 protein-lipid complex assembly 2/445 31/18722 0.167473576649003 0.438702184614477 APOE/APOC1 2 GO:0070528 protein kinase C signaling 2/445 31/18722 0.167473576649003 0.438702184614477 MYADM/AKAP12 2 GO:0090162 establishment of epithelial cell polarity 2/445 31/18722 0.167473576649003 0.438702184614477 RHOA/GOLPH3 2 GO:0090183 regulation of kidney development 2/445 31/18722 0.167473576649003 0.438702184614477 BASP1/GATA3 2 GO:1901797 negative regulation of signal transduction by p53 class mediator 2/445 31/18722 0.167473576649003 0.438702184614477 CD74/ING2 2 GO:2000144 positive regulation of DNA-templated transcription, initiation 2/445 31/18722 0.167473576649003 0.438702184614477 MED4/JUN 2 GO:0050769 positive regulation of neurogenesis 8/445 225/18722 0.168583308791539 0.441329308376329 SKIL/CTNNB1/SPINT1/SHTN1/GOLGA4/LRP2/SERPINF1/MACF1 8 GO:0050890 cognition 10/445 296/18722 0.169063441738716 0.4423059390897 FOS/APOE/HLA-DRA/CEBPB/JUN/UBA6/EIF2AK4/EIF4A3/PLK2/SERPINF1 10 GO:0002753 cytoplasmic pattern recognition receptor signaling pathway 3/445 60/18722 0.170903836004375 0.446040614132547 RIOK3/HSPA1B/LSM14A 3 GO:0042306 regulation of protein import into nucleus 3/445 60/18722 0.170903836004375 0.446040614132547 NUTF2/NUP58/HSP90AB1 3 GO:0001657 ureteric bud development 4/445 91/18722 0.17103082371967 0.446040614132547 SFRP1/CTNNB1/BASP1/GATA3 4 GO:0060191 regulation of lipase activity 4/445 91/18722 0.17103082371967 0.446040614132547 APOC1/ANXA1/ANGPTL4/RHOA 4 GO:0072080 nephron tubule development 4/445 91/18722 0.17103082371967 0.446040614132547 CTNNB1/IRX2/WWTR1/GATA3 4 GO:0002703 regulation of leukocyte mediated immunity 8/445 226/18722 0.171420350386455 0.446343867691953 HLA-B/HLA-DRA/HLA-DRB1/TYROBP/HMOX1/HLA-A/GATA3/VAMP8 8 GO:2000377 regulation of reactive oxygen species metabolic process 6/445 157/18722 0.171454699797868 0.446343867691953 PAGE4/TYROBP/BNIP3/GSTP1/GRB2/RHOA 6 GO:1990778 protein localization to cell periphery 11/445 333/18722 0.171471246193931 0.446343867691953 MYADM/GOPC/PKP3/GOLGA4/PKP2/MACF1/RAB8B/RDX/GBP1/GOLPH3/VAMP8 11 GO:0043410 positive regulation of MAPK cascade 15/445 480/18722 0.172057715405158 0.447588427165433 APOE/CD74/STK3/WNT7A/ARHGEF5/CTNNB1/HLA-DRB1/RAP1B/SEMA4C/EIF2AK2/FERMT2/SASH1/RB1CC1/AKAP12/LAPTM5 15 GO:0001909 leukocyte mediated cytotoxicity 5/445 124/18722 0.173263604914969 0.450441757019345 HLA-B/HLA-DRA/HLA-DRB1/TYROBP/HLA-A 5 GO:0048511 rhythmic process 10/445 298/18722 0.173997982074834 0.451556551529335 JUND/CBX3/JUN/ADAMTS1/NFIL3/SERPINF1/PPARG/HNRNPR/ATF4/NRIP1 10 GO:0043488 regulation of mRNA stability 6/445 158/18722 0.174928584105936 0.451556551529335 VIM/MEX3D/HNRNPM/YBX1/SERBP1/HNRNPR 6 GO:0048525 negative regulation of viral process 4/445 92/18722 0.175702506017354 0.451556551529335 EIF2AK2/GSN/MX1/PLSCR1 4 GO:0072163 mesonephric epithelium development 4/445 92/18722 0.175702506017354 0.451556551529335 SFRP1/CTNNB1/BASP1/GATA3 4 GO:0072164 mesonephric tubule development 4/445 92/18722 0.175702506017354 0.451556551529335 SFRP1/CTNNB1/BASP1/GATA3 4 GO:0003018 vascular process in circulatory system 9/445 263/18722 0.175986896987836 0.451556551529335 APOE/SLC2A3/FERMT2/SLC7A1/LRP2/AKAP12/TJP1/SLC7A5/RHOA 9 GO:0003338 metanephros morphogenesis 2/445 32/18722 0.175987908003445 0.451556551529335 CTNNB1/BASP1 2 GO:0009954 proximal/distal pattern formation 2/445 32/18722 0.175987908003445 0.451556551529335 CTNNB1/IRX2 2 GO:0010039 response to iron ion 2/445 32/18722 0.175987908003445 0.451556551529335 HMOX1/C1QA 2 GO:0010644 cell communication by electrical coupling 2/445 32/18722 0.175987908003445 0.451556551529335 SRI/PKP2 2 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway 2/445 32/18722 0.175987908003445 0.451556551529335 ING2/HSP90AB1 2 GO:0034367 protein-containing complex remodeling 2/445 32/18722 0.175987908003445 0.451556551529335 APOE/APOC1 2 GO:0035456 response to interferon-beta 2/445 32/18722 0.175987908003445 0.451556551529335 IRF1/PLSCR1 2 GO:0046475 glycerophospholipid catabolic process 2/445 32/18722 0.175987908003445 0.451556551529335 APOC1/GDPD3 2 GO:0050685 positive regulation of mRNA processing 2/445 32/18722 0.175987908003445 0.451556551529335 NCL/RBM3 2 GO:0051497 negative regulation of stress fiber assembly 2/445 32/18722 0.175987908003445 0.451556551529335 PAK2/TJP1 2 GO:0061037 negative regulation of cartilage development 2/445 32/18722 0.175987908003445 0.451556551529335 CTNNB1/EFEMP1 2 GO:0090140 regulation of mitochondrial fission 2/445 32/18722 0.175987908003445 0.451556551529335 BNIP3/PPARG 2 GO:0097345 mitochondrial outer membrane permeabilization 2/445 32/18722 0.175987908003445 0.451556551529335 BNIP3/BNIP3L 2 GO:1903846 positive regulation of cellular response to transforming growth factor beta stimulus 2/445 32/18722 0.175987908003445 0.451556551529335 ING2/HSP90AB1 2 GO:1905476 negative regulation of protein localization to membrane 2/445 32/18722 0.175987908003445 0.451556551529335 GOPC/GBP1 2 GO:0043966 histone H3 acetylation 3/445 61/18722 0.176796273482534 0.452506447184851 SMARCB1/PHF14/GATA3 3 GO:0071384 cellular response to corticosteroid stimulus 3/445 61/18722 0.176796273482534 0.452506447184851 ANXA1/GSTP1/SERPINF1 3 GO:1904356 regulation of telomere maintenance via telomere lengthening 3/445 61/18722 0.176796273482534 0.452506447184851 CTNNB1/HNRNPA1/CCT6A 3 GO:2000401 regulation of lymphocyte migration 3/445 61/18722 0.176796273482534 0.452506447184851 WNK1/AIF1/RHOA 3 GO:0071621 granulocyte chemotaxis 5/445 125/18722 0.177235283209672 0.453068660234626 CD74/S100A9/ANXA1/S100A8/FCER1G 5 GO:2000027 regulation of animal organ morphogenesis 5/445 125/18722 0.177235283209672 0.453068660234626 WNT7A/SFRP1/CTNNB1/RHOA/GATA3 5 GO:0016050 vesicle organization 10/445 300/18722 0.178999821422485 0.45729638979362 ANXA1/SAMD9/TMF1/CHMP5/ARFGAP3/SRGN/RAB8B/GOLPH3/VAMP8/PDCD6 10 GO:0033157 regulation of intracellular protein transport 8/445 229/18722 0.180059541126095 0.459719384667428 NUTF2/NUP58/HAX1/SP100/BNIP3L/HSP90AB1/UBE2J1/TCF7L2 8 GO:0019217 regulation of fatty acid metabolic process 4/445 93/18722 0.180417347427401 0.459780420865264 APOC1/CD74/ANXA1/PPARG 4 GO:0032088 negative regulation of NF-kappaB transcription factor activity 4/445 93/18722 0.180417347427401 0.459780420865264 KLF4/TMSB4X/NLRP2/ANXA4 4 GO:0106027 neuron projection organization 4/445 93/18722 0.180417347427401 0.459780420865264 APOE/WNT7A/TANC2/ZMYND8 4 GO:0032386 regulation of intracellular transport 11/445 337/18722 0.180888228113673 0.460696220923295 NUTF2/IWS1/NUP58/HAX1/SP100/BNIP3L/HSP90AB1/KHDRBS1/RDX/UBE2J1/TCF7L2 11 GO:0030198 extracellular matrix organization 10/445 301/18722 0.181525600785983 0.462034662259331 P4HA1/SPINT1/ERO1A/ADAMTS1/COL17A1/CCDC80/CST3/IER3IP1/CTSS/RGCC 10 GO:0032615 interleukin-12 production 3/445 62/18722 0.182744156653445 0.463992692769134 HLA-B/IRF1/LAPTM5 3 GO:0032655 regulation of interleukin-12 production 3/445 62/18722 0.182744156653445 0.463992692769134 HLA-B/IRF1/LAPTM5 3 GO:0046173 polyol biosynthetic process 3/445 62/18722 0.182744156653445 0.463992692769134 IMPA2/ISYNA1/PTS 3 GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation 3/445 62/18722 0.182744156653445 0.463992692769134 INHA/PMEPA1/PPARG 3 GO:0030073 insulin secretion 7/445 195/18722 0.183423849463411 0.464343958371693 SFRP1/HLA-DRB1/SRI/ANXA1/SOX4/TCF7L2/FAM3B 7 GO:0043062 extracellular structure organization 10/445 302/18722 0.184067746505095 0.464343958371693 P4HA1/SPINT1/ERO1A/ADAMTS1/COL17A1/CCDC80/CST3/IER3IP1/CTSS/RGCC 10 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 13/445 412/18722 0.184527803095835 0.464343958371693 CTNNB1/UBXN2A/GABARAP/RYBP/PCNP/UBE2V2/MAN1A1/HSP90AB1/HSPA1B/PLK2/CALR/WWTR1/UBE2J1 13 GO:0010737 protein kinase A signaling 2/445 33/18722 0.184568574109494 0.464343958371693 AKAP12/RDX 2 GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway 2/445 33/18722 0.184568574109494 0.464343958371693 EPN2/PDCD6 2 GO:0034110 regulation of homotypic cell-cell adhesion 2/445 33/18722 0.184568574109494 0.464343958371693 JAK1/RDX 2 GO:0048048 embryonic eye morphogenesis 2/445 33/18722 0.184568574109494 0.464343958371693 FBN2/EFEMP1 2 GO:0048730 epidermis morphogenesis 2/445 33/18722 0.184568574109494 0.464343958371693 KLF4/CTNNB1 2 GO:0070570 regulation of neuron projection regeneration 2/445 33/18722 0.184568574109494 0.464343958371693 KLF4/SPP1 2 GO:0071763 nuclear membrane organization 2/445 33/18722 0.184568574109494 0.464343958371693 ANKLE2/UBXN2A 2 GO:0110110 positive regulation of animal organ morphogenesis 2/445 33/18722 0.184568574109494 0.464343958371693 CTNNB1/GATA3 2 GO:0120033 negative regulation of plasma membrane bounded cell projection assembly 2/445 33/18722 0.184568574109494 0.464343958371693 ODF2L/MAP4 2 GO:1902692 regulation of neuroblast proliferation 2/445 33/18722 0.184568574109494 0.464343958371693 CTNNB1/CTNNA1 2 GO:1903715 regulation of aerobic respiration 2/445 33/18722 0.184568574109494 0.464343958371693 BNIP3/RHOA 2 GO:1904031 positive regulation of cyclin-dependent protein kinase activity 2/445 33/18722 0.184568574109494 0.464343958371693 HSP90AB1/RGCC 2 GO:0002690 positive regulation of leukocyte chemotaxis 4/445 94/18722 0.185174016424742 0.464735031500978 CD74/WNK1/AIF1/CALR 4 GO:0048704 embryonic skeletal system morphogenesis 4/445 94/18722 0.185174016424742 0.464735031500978 MTHFD1L/OSR2/CTNNB1/EIF4A3 4 GO:0051702 biological process involved in interaction with symbiont 4/445 94/18722 0.185174016424742 0.464735031500978 APOE/SMARCB1/JUN/EIF2AK4 4 GO:0061326 renal tubule development 4/445 94/18722 0.185174016424742 0.464735031500978 CTNNB1/IRX2/WWTR1/GATA3 4 GO:0071674 mononuclear cell migration 7/445 196/18722 0.186639717673068 0.468129127934088 ANXA1/WNK1/RPS19/AIF1/CALR/RHOA/GATA3 7 GO:0002704 negative regulation of leukocyte mediated immunity 3/445 63/18722 0.188744718646723 0.472834707537667 HLA-B/HMOX1/HLA-A 3 GO:0016239 positive regulation of macroautophagy 3/445 63/18722 0.188744718646723 0.472834707537667 BNIP3/HMOX1/BNIP3L 3 GO:0045229 external encapsulating structure organization 10/445 304/18722 0.189200500743885 0.473689253680598 P4HA1/SPINT1/ERO1A/ADAMTS1/COL17A1/CCDC80/CST3/IER3IP1/CTSS/RGCC 10 GO:0010498 proteasomal protein catabolic process 15/445 490/18722 0.191881903690807 0.479076076311206 APOE/CTNNB1/UBXN2A/GABARAP/RYBP/PCNP/TMF1/UBE2V2/MAN1A1/HSP90AB1/HSPA1B/PLK2/CALR/WWTR1/UBE2J1 15 GO:0061025 membrane fusion 6/445 163/18722 0.192718407429461 0.479076076311206 ANXA1/UBXN2A/SAMD9/MYOF/RAB8B/VAMP8 6 GO:0071322 cellular response to carbohydrate stimulus 6/445 163/18722 0.192718407429461 0.479076076311206 HLA-DRB1/SRI/SMARCB1/SOX4/SERPINF1/PIK3CA 6 GO:0002183 cytoplasmic translational initiation 2/445 34/18722 0.193207635713984 0.479076076311206 EIF4H/DENR 2 GO:0007616 long-term memory 2/445 34/18722 0.193207635713984 0.479076076311206 APOE/EIF2AK4 2 GO:0009303 rRNA transcription 2/445 34/18722 0.193207635713984 0.479076076311206 NCL/SMARCB1 2 GO:0010661 positive regulation of muscle cell apoptotic process 2/445 34/18722 0.193207635713984 0.479076076311206 BNIP3/PPARG 2 GO:0010922 positive regulation of phosphatase activity 2/445 34/18722 0.193207635713984 0.479076076311206 PPP1R15A/HSP90AB1 2 GO:0014072 response to isoquinoline alkaloid 2/445 34/18722 0.193207635713984 0.479076076311206 FOSB/AIF1 2 GO:0039528 cytoplasmic pattern recognition receptor signaling pathway in response to virus 2/445 34/18722 0.193207635713984 0.479076076311206 RIOK3/LSM14A 2 GO:0043276 anoikis 2/445 34/18722 0.193207635713984 0.479076076311206 MCL1/PIK3CA 2 GO:0043278 response to morphine 2/445 34/18722 0.193207635713984 0.479076076311206 FOSB/AIF1 2 GO:0070884 regulation of calcineurin-NFAT signaling cascade 2/445 34/18722 0.193207635713984 0.479076076311206 FHL2/CAMTA1 2 GO:1904893 negative regulation of receptor signaling pathway via STAT 2/445 34/18722 0.193207635713984 0.479076076311206 PARP14/PPARG 2 GO:1990000 amyloid fibril formation 2/445 34/18722 0.193207635713984 0.479076076311206 APOE/GSN 2 GO:2000352 negative regulation of endothelial cell apoptotic process 2/445 34/18722 0.193207635713984 0.479076076311206 ANGPTL4/GATA3 2 GO:0030888 regulation of B cell proliferation 3/445 64/18722 0.194795216831476 0.480734608418995 CD74/TYROBP/PAWR 3 GO:0045995 regulation of embryonic development 3/445 64/18722 0.194795216831476 0.480734608418995 CTNNB1/CCSAP/PHLDA2 3 GO:0046854 phosphatidylinositol phosphate biosynthetic process 3/445 64/18722 0.194795216831476 0.480734608418995 IMPA2/SMG1/PIK3CA 3 GO:0046888 negative regulation of hormone secretion 3/445 64/18722 0.194795216831476 0.480734608418995 SFRP1/INHA/RAB11FIP1 3 GO:0048857 neural nucleus development 3/445 64/18722 0.194795216831476 0.480734608418995 MAPKAP1/BASP1/RHOA 3 GO:1903051 negative regulation of proteolysis involved in cellular protein catabolic process 3/445 64/18722 0.194795216831476 0.480734608418995 RYBP/RPL23/HSP90AB1 3 GO:0003073 regulation of systemic arterial blood pressure 4/445 96/18722 0.194807488378939 0.480734608418995 TPM1/WNK1/NAV2/RHOA 4 GO:0015914 phospholipid transport 4/445 96/18722 0.194807488378939 0.480734608418995 APOE/APOC1/PLSCR1/DBI 4 GO:0002700 regulation of production of molecular mediator of immune response 6/445 164/18722 0.19635691333458 0.484268900886657 CD74/HMOX1/HLA-A/SLC7A5/LAPTM5/GATA3 6 GO:0006352 DNA-templated transcription, initiation 5/445 130/18722 0.19759146682034 0.48673246835708 MED4/TAF7/SMARCB1/JUN/RSF1 5 GO:0007098 centrosome cycle 5/445 130/18722 0.19759146682034 0.48673246835708 CTNNB1/CENPJ/GOLGA2/CHMP5/PLK2 5 GO:0009314 response to radiation 14/445 456/18722 0.199194572597056 0.487552572383103 FOS/JUND/SFRP1/ANXA1/RHOB/JUN/HMGN1/EIF2AK4/NET1/ADIRF/CBL/GRB2/ATF4/GATA3 14 GO:0002440 production of molecular mediator of immune response 10/445 308/18722 0.199655263089609 0.487552572383103 CD74/HLA-DRA/HLA-DRB1/HMOX1/HLA-DPA1/HLA-A/HLA-DPB1/SLC7A5/LAPTM5/GATA3 10 GO:0070167 regulation of biomineral tissue development 4/445 97/18722 0.199681608986754 0.487552572383103 OSR2/CEBPB/FBN2/SRGN 4 GO:0071902 positive regulation of protein serine/threonine kinase activity 7/445 200/18722 0.199730776880336 0.487552572383103 STK3/ARHGEF5/FERMT2/SASH1/HSP90AB1/RGCC/RHOA 7 GO:0007286 spermatid development 6/445 165/18722 0.200021060113964 0.487552572383103 ING2/HSPA2/FNDC3A/TMF1/CDYL/UBE2J1 6 GO:0038034 signal transduction in absence of ligand 3/445 65/18722 0.200892935008009 0.487552572383103 HSPA1B/MCL1/CTNNA1 3 GO:0045453 bone resorption 3/445 65/18722 0.200892935008009 0.487552572383103 CA2/CTNNB1/SPP1 3 GO:0048524 positive regulation of viral process 3/445 65/18722 0.200892935008009 0.487552572383103 CD74/HLA-DRB1/RSF1 3 GO:0048645 animal organ formation 3/445 65/18722 0.200892935008009 0.487552572383103 CTNNB1/PIM1/LRP2 3 GO:0060389 pathway-restricted SMAD protein phosphorylation 3/445 65/18722 0.200892935008009 0.487552572383103 INHA/PMEPA1/PPARG 3 GO:0072577 endothelial cell apoptotic process 3/445 65/18722 0.200892935008009 0.487552572383103 ANGPTL4/RGCC/GATA3 3 GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand 3/445 65/18722 0.200892935008009 0.487552572383103 HSPA1B/MCL1/CTNNA1 3 GO:1902475 L-alpha-amino acid transmembrane transport 3/445 65/18722 0.200892935008009 0.487552572383103 SLC7A1/SLC1A6/SLC7A5 3 GO:1905330 regulation of morphogenesis of an epithelium 3/445 65/18722 0.200892935008009 0.487552572383103 SFRP1/CTNNB1/GATA3 3 GO:0000209 protein polyubiquitination 8/445 236/18722 0.200931792223819 0.487552572383103 CTNNB1/UBE2V1/GABARAP/UBE2D1/UBE2V2/SASH1/CBL/UBE2J1 8 GO:0030072 peptide hormone secretion 8/445 236/18722 0.200931792223819 0.487552572383103 SFRP1/HLA-DRB1/SRI/ANXA1/SOX4/RAB8B/TCF7L2/FAM3B 8 GO:0006471 protein ADP-ribosylation 2/445 35/18722 0.201897491925576 0.487552572383103 PUM3/PARP14 2 GO:0009119 ribonucleoside metabolic process 2/445 35/18722 0.201897491925576 0.487552572383103 AMD1/CDA 2 GO:0010765 positive regulation of sodium ion transport 2/445 35/18722 0.201897491925576 0.487552572383103 PKP2/WNK1 2 GO:0018149 peptide cross-linking 2/445 35/18722 0.201897491925576 0.487552572383103 ANXA1/DSP 2 GO:0019068 virion assembly 2/445 35/18722 0.201897491925576 0.487552572383103 APOE/CHMP5 2 GO:0032232 negative regulation of actin filament bundle assembly 2/445 35/18722 0.201897491925576 0.487552572383103 PAK2/TJP1 2 GO:0032350 regulation of hormone metabolic process 2/445 35/18722 0.201897491925576 0.487552572383103 TCF7L2/GATA3 2 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 2/445 35/18722 0.201897491925576 0.487552572383103 RYBP/HSP90AB1 2 GO:0034405 response to fluid shear stress 2/445 35/18722 0.201897491925576 0.487552572383103 KLF4/CA2 2 GO:0043243 positive regulation of protein-containing complex disassembly 2/445 35/18722 0.201897491925576 0.487552572383103 DSTN/BNIP3 2 GO:0045454 cell redox homeostasis 2/445 35/18722 0.201897491925576 0.487552572383103 ERO1A/ERP44 2 GO:0045880 positive regulation of smoothened signaling pathway 2/445 35/18722 0.201897491925576 0.487552572383103 SFRP1/CTNNA1 2 GO:0046640 regulation of alpha-beta T cell proliferation 2/445 35/18722 0.201897491925576 0.487552572383103 IRF1/HLA-A 2 GO:0086005 ventricular cardiac muscle cell action potential 2/445 35/18722 0.201897491925576 0.487552572383103 PKP2/DSP 2 GO:0106056 regulation of calcineurin-mediated signaling 2/445 35/18722 0.201897491925576 0.487552572383103 FHL2/CAMTA1 2 GO:1901361 organic cyclic compound catabolic process 15/445 495/18722 0.202189050907479 0.487552572383103 APOE/DFFB/VIM/SPP1/HMOX1/PKP3/MEX3D/SMG1/HNRNPM/YBX1/EIF4A3/HSPA1B/SERBP1/HNRNPR/CDA 15 GO:0043112 receptor metabolic process 6/445 166/18722 0.203710320525319 0.487552572383103 APOE/FCER1G/CHMP5/CD63/GRB2/LAPTM5 6 GO:0060538 skeletal muscle organ development 6/445 166/18722 0.203710320525319 0.487552572383103 FOS/IGSF8/CTNNB1/BASP1/KLF5/RHOA 6 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 4/445 98/18722 0.204592194670521 0.487552572383103 CD74/ING2/MCL1/DNAJA1 4 GO:0032409 regulation of transporter activity 10/445 310/18722 0.204974555479432 0.487552572383103 TMSB4X/SRI/GOPC/PIM1/HSPA2/RXRA/WNK1/PPARG/CTSS/NDUFA4 10 GO:0014706 striated muscle tissue development 12/445 384/18722 0.205266900347373 0.487552572383103 FOS/TPM1/IGSF8/CTNNB1/PIM1/PKP2/LRP2/KLF5/CALR/FHL2/DSP/RHOA 12 GO:0050922 negative regulation of chemotaxis 3/445 66/18722 0.207035185440471 0.487552572383103 SEMA4C/GSTP1/AIF1 3 GO:0072678 T cell migration 3/445 66/18722 0.207035185440471 0.487552572383103 WNK1/AIF1/RHOA 3 GO:0034767 positive regulation of ion transmembrane transport 6/445 167/18722 0.207424162702178 0.487552572383103 TMSB4X/SRI/HSPA2/WNK1/CTSS/NDUFA4 6 GO:0043270 positive regulation of ion transport 9/445 275/18722 0.209316205526435 0.487552572383103 TMSB4X/CEBPB/SRI/HSPA2/PKP2/WNK1/CTSS/VAMP8/NDUFA4 9 GO:0000045 autophagosome assembly 4/445 99/18722 0.209537901166845 0.487552572383103 ATG12/UBXN2A/GABARAP/RB1CC1 4 GO:0002444 myeloid leukocyte mediated immunity 4/445 99/18722 0.209537901166845 0.487552572383103 TYROBP/HMOX1/CBL/VAMP8 4 GO:0021549 cerebellum development 4/445 99/18722 0.209537901166845 0.487552572383103 WNT7A/SEMA4C/UQCRQ/AIF1 4 GO:0030838 positive regulation of actin filament polymerization 4/445 99/18722 0.209537901166845 0.487552572383103 CDC42EP3/GSN/GRB2/RHOA 4 GO:0042100 B cell proliferation 4/445 99/18722 0.209537901166845 0.487552572383103 CD74/TYROBP/PAWR/PLCL2 4 GO:0060291 long-term synaptic potentiation 4/445 99/18722 0.209537901166845 0.487552572383103 APOE/TYROBP/EIF2AK4/PLK2 4 GO:0110149 regulation of biomineralization 4/445 99/18722 0.209537901166845 0.487552572383103 OSR2/CEBPB/FBN2/SRGN 4 GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process 5/445 133/18722 0.210175110784031 0.487552572383103 GABARAP/UBE2V2/HSPA1B/PLK2/LAPTM5 5 GO:0010092 specification of animal organ identity 2/445 36/18722 0.210630868675928 0.487552572383103 CTNNB1/LRP2 2 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus 2/445 36/18722 0.210630868675928 0.487552572383103 HLA-DRB1/SRI 2 GO:0042119 neutrophil activation 2/445 36/18722 0.210630868675928 0.487552572383103 TYROBP/FCER1G 2 GO:0044060 regulation of endocrine process 2/445 36/18722 0.210630868675928 0.487552572383103 INHA/RAB8B 2 GO:0051385 response to mineralocorticoid 2/445 36/18722 0.210630868675928 0.487552572383103 FOS/FOSB 2 GO:0070897 transcription preinitiation complex assembly 2/445 36/18722 0.210630868675928 0.487552572383103 TAF7/SMARCB1 2 GO:0090322 regulation of superoxide metabolic process 2/445 36/18722 0.210630868675928 0.487552572383103 TYROBP/GSTP1 2 GO:0099173 postsynapse organization 6/445 168/18722 0.211162050441427 0.487552572383103 APOE/WNT7A/TANC2/ZMYND8/NDRG1/SRGN 6 GO:2000241 regulation of reproductive process 6/445 168/18722 0.211162050441427 0.487552572383103 STK3/SFRP1/CTNNB1/PHLDA2/SERPINF1/CALR 6 GO:0009100 glycoprotein metabolic process 12/445 387/18722 0.21251161777275 0.487552572383103 CTNNB1/PAWR/GOLGA2/GALNT1/MAN1A1/HS6ST1/TMEM165/ERP44/CST3/UBE2J1/GOLPH3/TCF7L2 12 GO:0002449 lymphocyte mediated immunity 11/445 350/18722 0.213091053785917 0.487552572383103 CD74/HLA-B/HLA-DRA/HLA-DRB1/FCER1G/HLA-DPA1/HLA-A/C1QB/HLA-DPB1/C1QA/GATA3 11 GO:0006513 protein monoubiquitination 3/445 67/18722 0.213219310737688 0.487552572383103 RYBP/CBL/PDCD6 3 GO:0009880 embryonic pattern specification 3/445 67/18722 0.213219310737688 0.487552572383103 WNT7A/CTNNB1/BASP1 3 GO:0042130 negative regulation of T cell proliferation 3/445 67/18722 0.213219310737688 0.487552572383103 CEBPB/HLA-DRB1/PAWR 3 GO:0061180 mammary gland epithelium development 3/445 67/18722 0.213219310737688 0.487552572383103 CEBPB/LBH/GATA3 3 GO:0032886 regulation of microtubule-based process 8/445 240/18722 0.213279885056315 0.487552572383103 CCSAP/CENPJ/RASSF7/CHMP5/HSPA1B/PLK2/MACF1/RHOA 8 GO:0000492 box C/D snoRNP assembly 1/445 10/18722 0.213857482730134 0.487552572383103 ZNHIT6 1 GO:0001672 regulation of chromatin assembly or disassembly 1/445 10/18722 0.213857482730134 0.487552572383103 SPTY2D1 1 GO:0002524 hypersensitivity 1/445 10/18722 0.213857482730134 0.487552572383103 GATA3 1 GO:0002887 negative regulation of myeloid leukocyte mediated immunity 1/445 10/18722 0.213857482730134 0.487552572383103 HMOX1 1 GO:0003056 regulation of vascular associated smooth muscle contraction 1/445 10/18722 0.213857482730134 0.487552572383103 RHOA 1 GO:0003183 mitral valve morphogenesis 1/445 10/18722 0.213857482730134 0.487552572383103 SOX4 1 GO:0006283 transcription-coupled nucleotide-excision repair 1/445 10/18722 0.213857482730134 0.487552572383103 HMGN1 1 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway 1/445 10/18722 0.213857482730134 0.487552572383103 GNB1 1 GO:0009396 folic acid-containing compound biosynthetic process 1/445 10/18722 0.213857482730134 0.487552572383103 MTHFD1L 1 GO:0010968 regulation of microtubule nucleation 1/445 10/18722 0.213857482730134 0.487552572383103 HSPA1B 1 GO:0016081 synaptic vesicle docking 1/445 10/18722 0.213857482730134 0.487552572383103 CTBP2 1 GO:0018242 protein O-linked glycosylation via serine 1/445 10/18722 0.213857482730134 0.487552572383103 GALNT1 1 GO:0019062 virion attachment to host cell 1/445 10/18722 0.213857482730134 0.487552572383103 HSP90AB1 1 GO:0021548 pons development 1/445 10/18722 0.213857482730134 0.487552572383103 UQCRQ 1 GO:0030953 astral microtubule organization 1/445 10/18722 0.213857482730134 0.487552572383103 CENPJ 1 GO:0031340 positive regulation of vesicle fusion 1/445 10/18722 0.213857482730134 0.487552572383103 ANXA1 1 GO:0032253 dense core granule localization 1/445 10/18722 0.213857482730134 0.487552572383103 TANC2 1 GO:0035646 endosome to melanosome transport 1/445 10/18722 0.213857482730134 0.487552572383103 CD63 1 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway 1/445 10/18722 0.213857482730134 0.487552572383103 GATA3 1 GO:0035999 tetrahydrofolate interconversion 1/445 10/18722 0.213857482730134 0.487552572383103 MTHFD1L 1 GO:0036363 transforming growth factor beta activation 1/445 10/18722 0.213857482730134 0.487552572383103 HSP90AB1 1 GO:0038007 netrin-activated signaling pathway 1/445 10/18722 0.213857482730134 0.487552572383103 SHTN1 1 GO:0042711 maternal behavior 1/445 10/18722 0.213857482730134 0.487552572383103 MBD2 1 GO:0042996 regulation of Golgi to plasma membrane protein transport 1/445 10/18722 0.213857482730134 0.487552572383103 GOPC 1 GO:0043485 endosome to pigment granule transport 1/445 10/18722 0.213857482730134 0.487552572383103 CD63 1 GO:0044848 biological phase 1/445 10/18722 0.213857482730134 0.487552572383103 CTNNB1 1 GO:0045625 regulation of T-helper 1 cell differentiation 1/445 10/18722 0.213857482730134 0.487552572383103 ANXA1 1 GO:0048671 negative regulation of collateral sprouting 1/445 10/18722 0.213857482730134 0.487552572383103 SPP1 1 GO:0048703 embryonic viscerocranium morphogenesis 1/445 10/18722 0.213857482730134 0.487552572383103 MTHFD1L 1 GO:0048757 pigment granule maturation 1/445 10/18722 0.213857482730134 0.487552572383103 CD63 1 GO:0051351 positive regulation of ligase activity 1/445 10/18722 0.213857482730134 0.487552572383103 TMSB4X 1 GO:0051409 response to nitrosative stress 1/445 10/18722 0.213857482730134 0.487552572383103 DNAJA1 1 GO:0060068 vagina development 1/445 10/18722 0.213857482730134 0.487552572383103 LRP2 1 GO:0060368 regulation of Fc receptor mediated stimulatory signaling pathway 1/445 10/18722 0.213857482730134 0.487552572383103 PLSCR1 1 GO:0060439 trachea morphogenesis 1/445 10/18722 0.213857482730134 0.487552572383103 CTNNB1 1 GO:0060525 prostate glandular acinus development 1/445 10/18722 0.213857482730134 0.487552572383103 SFRP1 1 GO:0060736 prostate gland growth 1/445 10/18722 0.213857482730134 0.487552572383103 PSAP 1 GO:0061085 regulation of histone H3-K27 methylation 1/445 10/18722 0.213857482730134 0.487552572383103 GATA3 1 GO:0070862 negative regulation of protein exit from endoplasmic reticulum 1/445 10/18722 0.213857482730134 0.487552572383103 UBE2J1 1 GO:0071421 manganese ion transmembrane transport 1/445 10/18722 0.213857482730134 0.487552572383103 TMEM165 1 GO:0071803 positive regulation of podosome assembly 1/445 10/18722 0.213857482730134 0.487552572383103 RHOA 1 GO:0072070 loop of Henle development 1/445 10/18722 0.213857482730134 0.487552572383103 IRX2 1 GO:0072178 nephric duct morphogenesis 1/445 10/18722 0.213857482730134 0.487552572383103 GATA3 1 GO:0090043 regulation of tubulin deacetylation 1/445 10/18722 0.213857482730134 0.487552572383103 BEX4 1 GO:0090179 planar cell polarity pathway involved in neural tube closure 1/445 10/18722 0.213857482730134 0.487552572383103 SFRP1 1 GO:0090209 negative regulation of triglyceride metabolic process 1/445 10/18722 0.213857482730134 0.487552572383103 APOE 1 GO:0090527 actin filament reorganization 1/445 10/18722 0.213857482730134 0.487552572383103 GSN 1 GO:0097250 mitochondrial respirasome assembly 1/445 10/18722 0.213857482730134 0.487552572383103 HIGD1A 1 GO:0097278 complement-dependent cytotoxicity 1/445 10/18722 0.213857482730134 0.487552572383103 HSP90AB1 1 GO:0098885 modification of postsynaptic actin cytoskeleton 1/445 10/18722 0.213857482730134 0.487552572383103 RHOA 1 GO:0099519 dense core granule cytoskeletal transport 1/445 10/18722 0.213857482730134 0.487552572383103 TANC2 1 GO:1901203 positive regulation of extracellular matrix assembly 1/445 10/18722 0.213857482730134 0.487552572383103 RGCC 1 GO:1901950 dense core granule transport 1/445 10/18722 0.213857482730134 0.487552572383103 TANC2 1 GO:1902023 L-arginine transport 1/445 10/18722 0.213857482730134 0.487552572383103 SLC7A1 1 GO:1902855 regulation of non-motile cilium assembly 1/445 10/18722 0.213857482730134 0.487552572383103 MAP4 1 GO:1902946 protein localization to early endosome 1/445 10/18722 0.213857482730134 0.487552572383103 RDX 1 GO:1903826 arginine transmembrane transport 1/445 10/18722 0.213857482730134 0.487552572383103 SLC7A1 1 GO:1904338 regulation of dopaminergic neuron differentiation 1/445 10/18722 0.213857482730134 0.487552572383103 SFRP1 1 GO:1904350 regulation of protein catabolic process in the vacuole 1/445 10/18722 0.213857482730134 0.487552572383103 LRP2 1 GO:1904851 positive regulation of establishment of protein localization to telomere 1/445 10/18722 0.213857482730134 0.487552572383103 CCT6A 1 GO:1904896 ESCRT complex disassembly 1/445 10/18722 0.213857482730134 0.487552572383103 CHMP5 1 GO:1904903 ESCRT III complex disassembly 1/445 10/18722 0.213857482730134 0.487552572383103 CHMP5 1 GO:1905383 protein localization to presynapse 1/445 10/18722 0.213857482730134 0.487552572383103 WNT7A 1 GO:1990253 cellular response to leucine starvation 1/445 10/18722 0.213857482730134 0.487552572383103 EIF2AK4 1 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus 1/445 10/18722 0.213857482730134 0.487552572383103 EIF4A3 1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin 1/445 10/18722 0.213857482730134 0.487552572383103 RGCC 1 GO:2000510 positive regulation of dendritic cell chemotaxis 1/445 10/18722 0.213857482730134 0.487552572383103 CALR 1 GO:2000674 regulation of type B pancreatic cell apoptotic process 1/445 10/18722 0.213857482730134 0.487552572383103 TCF7L2 1 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 1/445 10/18722 0.213857482730134 0.487552572383103 CTNNA1 1 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 1/445 10/18722 0.213857482730134 0.487552572383103 GSN 1 GO:0061041 regulation of wound healing 5/445 134/18722 0.214426518235303 0.488517815161661 APOE/ANXA1/FERMT2/PLPP3/CLDN19 5 GO:0044728 DNA methylation or demethylation 4/445 100/18722 0.214517384822865 0.488517815161661 FOS/MBD2/PIK3CA/GATA3 4 GO:0006937 regulation of muscle contraction 6/445 169/18722 0.214923443488356 0.48917286228672 TPM1/TNNI2/SRI/PKP2/DSP/RHOA 6 GO:0060047 heart contraction 8/445 241/18722 0.216411922572841 0.492289456028857 TPM1/TNNI2/SRI/GSN/THRB/PKP2/PIK3CA/DSP 8 GO:0007281 germ cell development 9/445 278/18722 0.218026307663124 0.49394093302854 CTNNB1/ING2/HSPA2/FNDC3A/TMF1/CDYL/YTHDC1/GMCL1/UBE2J1 9 GO:0006887 exocytosis 11/445 352/18722 0.218248971324435 0.49394093302854 WNT7A/TNFAIP2/RAP1B/ANXA1/HMOX1/MICAL3/CTBP2/CBL/RAB8B/VAMP8/RAB11FIP1 11 GO:0031331 positive regulation of cellular catabolic process 13/445 427/18722 0.218480010453451 0.49394093302854 APOE/GABARAP/BNIP3/HMOX1/BNIP3L/MEX3D/LRP2/UBE2V2/HSPA1B/PLK2/HNRNPR/RDX/LAPTM5 13 GO:0001101 response to acid chemical 5/445 135/18722 0.218705005880368 0.49394093302854 CEBPB/KRT8/GSTP1/PIK3CA/RHOA 5 GO:0002687 positive regulation of leukocyte migration 5/445 135/18722 0.218705005880368 0.49394093302854 CD74/WNK1/AIF1/CALR/RHOA 5 GO:0042157 lipoprotein metabolic process 5/445 135/18722 0.218705005880368 0.49394093302854 APOE/APOC1/ATG12/CTSD/DBI 5 GO:0030178 negative regulation of Wnt signaling pathway 6/445 170/18722 0.218707797819059 0.49394093302854 APOE/STK3/SFRP1/RNF213/WWTR1/TCF7L2 6 GO:0043487 regulation of RNA stability 6/445 170/18722 0.218707797819059 0.49394093302854 VIM/MEX3D/HNRNPM/YBX1/SERBP1/HNRNPR 6 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 2/445 37/18722 0.219400807536251 0.49394093302854 SMG1/EIF4A3 2 GO:0002369 T cell cytokine production 2/445 37/18722 0.219400807536251 0.49394093302854 HLA-A/GATA3 2 GO:0002724 regulation of T cell cytokine production 2/445 37/18722 0.219400807536251 0.49394093302854 HLA-A/GATA3 2 GO:0006904 vesicle docking involved in exocytosis 2/445 37/18722 0.219400807536251 0.49394093302854 CTBP2/RAB8B 2 GO:0033363 secretory granule organization 2/445 37/18722 0.219400807536251 0.49394093302854 TMF1/SRGN 2 GO:0034260 negative regulation of GTPase activity 2/445 37/18722 0.219400807536251 0.49394093302854 WNK1/RDX 2 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway 2/445 37/18722 0.219400807536251 0.49394093302854 CTNNB1/GATA3 2 GO:0071542 dopaminergic neuron differentiation 2/445 37/18722 0.219400807536251 0.49394093302854 SFRP1/CTNNB1 2 GO:1905332 positive regulation of morphogenesis of an epithelium 2/445 37/18722 0.219400807536251 0.49394093302854 CTNNB1/GATA3 2 GO:0042698 ovulation cycle 3/445 68/18722 0.21944268558919 0.49394093302854 ADAMTS1/SERPINF1/NRIP1 3 GO:0061912 selective autophagy 3/445 68/18722 0.21944268558919 0.49394093302854 RB1CC1/CDC37/UFC1 3 GO:0006576 cellular biogenic amine metabolic process 4/445 101/18722 0.21952930356824 0.49394093302854 GDPD3/SAT1/AMD1/GATA3 4 GO:0048863 stem cell differentiation 7/445 206/18722 0.220009140652556 0.494751094194725 WNT7A/SFRP1/CTNNB1/SEMA4C/EIF2AK2/LBH/PDCD6 7 GO:0046890 regulation of lipid biosynthetic process 6/445 171/18722 0.222514565920072 0.495961323414152 APOE/APOC1/LPCAT1/CD74/CGA/ANXA1 6 GO:0050679 positive regulation of epithelial cell proliferation 7/445 207/18722 0.22345881152473 0.495961323414152 OSR2/WNT7A/SFRP1/CTNNB1/HMOX1/TCF7L2/PDCD6 7 GO:0019439 aromatic compound catabolic process 14/445 467/18722 0.223567310092219 0.495961323414152 DFFB/VIM/HMOX1/PKP3/MEX3D/SMG1/HNRNPM/YBX1/EIF4A3/HSPA1B/PON2/SERBP1/HNRNPR/CDA 14 GO:0061564 axon development 14/445 467/18722 0.223567310092219 0.495961323414152 APOE/KLF4/SKIL/WNT7A/SPP1/SEMA4C/SHTN1/GOLGA4/RTN4RL2/PAK2/HSP90AB1/MACF1/CTNNA1/GATA3 14 GO:0006959 humoral immune response 10/445 317/18722 0.224050266483743 0.495961323414152 LYZ/RPL39/HLA-DRB1/S100A9/HLA-A/C1QB/RPS19/C1QA/RGCC/GATA3 10 GO:0009101 glycoprotein biosynthetic process 10/445 317/18722 0.224050266483743 0.495961323414152 CTNNB1/PAWR/GOLGA2/GALNT1/MAN1A1/HS6ST1/TMEM165/UBE2J1/GOLPH3/TCF7L2 10 GO:0010506 regulation of autophagy 10/445 317/18722 0.224050266483743 0.495961323414152 HAX1/BNIP3/HMOX1/GOLGA2/BNIP3L/SMG1/PLK2/MCL1/PIK3CA/PSAP 10 GO:0062014 negative regulation of small molecule metabolic process 4/445 102/18722 0.224572317853123 0.495961323414152 APOE/APOC1/FAM3C/CDA 4 GO:0015807 L-amino acid transport 3/445 69/18722 0.225702718363132 0.495961323414152 SLC7A1/SLC1A6/SLC7A5 3 GO:0045665 negative regulation of neuron differentiation 3/445 69/18722 0.225702718363132 0.495961323414152 EIF2AK4/CALR/RHOA 3 GO:0050805 negative regulation of synaptic transmission 3/445 69/18722 0.225702718363132 0.495961323414152 RAP1B/EIF4A3/PLK2 3 GO:0001678 cellular glucose homeostasis 6/445 172/18722 0.226343197065078 0.495961323414152 HLA-DRB1/SRI/SMARCB1/SOX4/SERPINF1/PIK3CA 6 GO:0048515 spermatid differentiation 6/445 172/18722 0.226343197065078 0.495961323414152 ING2/HSPA2/FNDC3A/TMF1/CDYL/UBE2J1 6 GO:0008203 cholesterol metabolic process 5/445 137/18722 0.227339962352142 0.495961323414152 APOE/LIMA1/RXRA/FDX1/OSBPL1A 5 GO:0090090 negative regulation of canonical Wnt signaling pathway 5/445 137/18722 0.227339962352142 0.495961323414152 APOE/STK3/SFRP1/WWTR1/TCF7L2 5 GO:0010719 negative regulation of epithelial to mesenchymal transition 2/445 38/18722 0.228200654878936 0.495961323414152 SFRP1/GATA3 2 GO:0030279 negative regulation of ossification 2/445 38/18722 0.228200654878936 0.495961323414152 SFRP1/SRGN 2 GO:0032941 secretion by tissue 2/445 38/18722 0.228200654878936 0.495961323414152 WNK1/VAMP8 2 GO:0046633 alpha-beta T cell proliferation 2/445 38/18722 0.228200654878936 0.495961323414152 IRF1/HLA-A 2 GO:0071392 cellular response to estradiol stimulus 2/445 38/18722 0.228200654878936 0.495961323414152 SFRP1/NRIP1 2 GO:0097242 amyloid-beta clearance 2/445 38/18722 0.228200654878936 0.495961323414152 APOE/LRP2 2 GO:1902110 positive regulation of mitochondrial membrane permeability involved in apoptotic process 2/445 38/18722 0.228200654878936 0.495961323414152 BNIP3/BNIP3L 2 GO:1903725 regulation of phospholipid metabolic process 2/445 38/18722 0.228200654878936 0.495961323414152 APOC1/LPCAT1 2 GO:0008202 steroid metabolic process 10/445 319/18722 0.22962523149553 0.495961323414152 APOE/APOC1/LIMA1/CGA/SPP1/HSD17B1/RXRA/LRP2/FDX1/OSBPL1A 10 GO:0002027 regulation of heart rate 4/445 103/18722 0.229645091552447 0.495961323414152 TPM1/SRI/PKP2/DSP 4 GO:0030593 neutrophil chemotaxis 4/445 103/18722 0.229645091552447 0.495961323414152 CD74/S100A9/S100A8/FCER1G 4 GO:1905037 autophagosome organization 4/445 103/18722 0.229645091552447 0.495961323414152 ATG12/UBXN2A/GABARAP/RB1CC1 4 GO:0071222 cellular response to lipopolysaccharide 7/445 209/18722 0.230414548442873 0.495961323414152 CEBPB/VIM/LITAF/GSTP1/SASH1/CHMP5/RHOA 7 GO:0032273 positive regulation of protein polymerization 5/445 138/18722 0.23169479609699 0.495961323414152 CDC42EP3/GSN/HSPA1B/GRB2/RHOA 5 GO:0002548 monocyte chemotaxis 3/445 70/18722 0.231996852572581 0.495961323414152 ANXA1/RPS19/AIF1 3 GO:0071216 cellular response to biotic stimulus 8/445 246/18722 0.232327368564421 0.495961323414152 CEBPB/VIM/LITAF/GSTP1/SASH1/CHMP5/TXNIP/RHOA 8 GO:0002604 regulation of dendritic cell antigen processing and presentation 1/445 11/18722 0.232553155035878 0.495961323414152 CD74 1 GO:0003139 secondary heart field specification 1/445 11/18722 0.232553155035878 0.495961323414152 LRP2 1 GO:0003157 endocardium development 1/445 11/18722 0.232553155035878 0.495961323414152 STK3 1 GO:0003174 mitral valve development 1/445 11/18722 0.232553155035878 0.495961323414152 SOX4 1 GO:0006707 cholesterol catabolic process 1/445 11/18722 0.232553155035878 0.495961323414152 APOE 1 GO:0010739 positive regulation of protein kinase A signaling 1/445 11/18722 0.232553155035878 0.495961323414152 AKAP12 1 GO:0010887 negative regulation of cholesterol storage 1/445 11/18722 0.232553155035878 0.495961323414152 PPARG 1 GO:0015810 aspartate transmembrane transport 1/445 11/18722 0.232553155035878 0.495961323414152 SLC1A6 1 GO:0016127 sterol catabolic process 1/445 11/18722 0.232553155035878 0.495961323414152 APOE 1 GO:0018342 protein prenylation 1/445 11/18722 0.232553155035878 0.495961323414152 CHML 1 GO:0019048 modulation by virus of host process 1/445 11/18722 0.232553155035878 0.495961323414152 RXRA 1 GO:0019372 lipoxygenase pathway 1/445 11/18722 0.232553155035878 0.495961323414152 HPGD 1 GO:0021860 pyramidal neuron development 1/445 11/18722 0.232553155035878 0.495961323414152 UQCRQ 1 GO:0032276 regulation of gonadotropin secretion 1/445 11/18722 0.232553155035878 0.495961323414152 INHA 1 GO:0033197 response to vitamin E 1/445 11/18722 0.232553155035878 0.495961323414152 SRSF2 1 GO:0033234 negative regulation of protein sumoylation 1/445 11/18722 0.232553155035878 0.495961323414152 CTNNB1 1 GO:0033327 Leydig cell differentiation 1/445 11/18722 0.232553155035878 0.495961323414152 TMF1 1 GO:0033483 gas homeostasis 1/445 11/18722 0.232553155035878 0.495961323414152 GSTP1 1 GO:0033632 regulation of cell-cell adhesion mediated by integrin 1/445 11/18722 0.232553155035878 0.495961323414152 WNK1 1 GO:0033860 regulation of NAD(P)H oxidase activity 1/445 11/18722 0.232553155035878 0.495961323414152 RFK 1 GO:0034350 regulation of glial cell apoptotic process 1/445 11/18722 0.232553155035878 0.495961323414152 AKAP12 1 GO:0034379 very-low-density lipoprotein particle assembly 1/445 11/18722 0.232553155035878 0.495961323414152 APOC1 1 GO:0035581 sequestering of extracellular ligand from receptor 1/445 11/18722 0.232553155035878 0.495961323414152 FBN2 1 GO:0039530 MDA-5 signaling pathway 1/445 11/18722 0.232553155035878 0.495961323414152 RIOK3 1 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway 1/445 11/18722 0.232553155035878 0.495961323414152 RIOK3 1 GO:0042167 heme catabolic process 1/445 11/18722 0.232553155035878 0.495961323414152 HMOX1 1 GO:0042447 hormone catabolic process 1/445 11/18722 0.232553155035878 0.495961323414152 SPP1 1 GO:0042451 purine nucleoside biosynthetic process 1/445 11/18722 0.232553155035878 0.495961323414152 AMD1 1 GO:0042455 ribonucleoside biosynthetic process 1/445 11/18722 0.232553155035878 0.495961323414152 AMD1 1 GO:0042670 retinal cone cell differentiation 1/445 11/18722 0.232553155035878 0.495961323414152 THRB 1 GO:0042789 mRNA transcription by RNA polymerase II 1/445 11/18722 0.232553155035878 0.495961323414152 ATF4 1 GO:0045060 negative thymic T cell selection 1/445 11/18722 0.232553155035878 0.495961323414152 CD74 1 GO:0045628 regulation of T-helper 2 cell differentiation 1/445 11/18722 0.232553155035878 0.495961323414152 ANXA1 1 GO:0046129 purine ribonucleoside biosynthetic process 1/445 11/18722 0.232553155035878 0.495961323414152 AMD1 1 GO:0046149 pigment catabolic process 1/445 11/18722 0.232553155035878 0.495961323414152 HMOX1 1 GO:0046549 retinal cone cell development 1/445 11/18722 0.232553155035878 0.495961323414152 THRB 1 GO:0046643 regulation of gamma-delta T cell activation 1/445 11/18722 0.232553155035878 0.495961323414152 SOX4 1 GO:0046929 negative regulation of neurotransmitter secretion 1/445 11/18722 0.232553155035878 0.495961323414152 RAP1B 1 GO:0048715 negative regulation of oligodendrocyte differentiation 1/445 11/18722 0.232553155035878 0.495961323414152 CTNNB1 1 GO:0051561 positive regulation of mitochondrial calcium ion concentration 1/445 11/18722 0.232553155035878 0.495961323414152 BNIP3 1 GO:0051573 negative regulation of histone H3-K9 methylation 1/445 11/18722 0.232553155035878 0.495961323414152 SMARCB1 1 GO:0051657 maintenance of organelle location 1/445 11/18722 0.232553155035878 0.495961323414152 ARHGAP21 1 GO:0055015 ventricular cardiac muscle cell development 1/445 11/18722 0.232553155035878 0.495961323414152 FHL2 1 GO:0060174 limb bud formation 1/445 11/18722 0.232553155035878 0.495961323414152 SOX4 1 GO:0060312 regulation of blood vessel remodeling 1/445 11/18722 0.232553155035878 0.495961323414152 CST3 1 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity 1/445 11/18722 0.232553155035878 0.495961323414152 SRI 1 GO:0060746 parental behavior 1/445 11/18722 0.232553155035878 0.495961323414152 MBD2 1 GO:0061029 eyelid development in camera-type eye 1/445 11/18722 0.232553155035878 0.495961323414152 OSR2 1 GO:0070203 regulation of establishment of protein localization to telomere 1/445 11/18722 0.232553155035878 0.495961323414152 CCT6A 1 GO:0070327 thyroid hormone transport 1/445 11/18722 0.232553155035878 0.495961323414152 SLC7A5 1 GO:0070601 centromeric sister chromatid cohesion 1/445 11/18722 0.232553155035878 0.495961323414152 CTNNB1 1 GO:0070778 L-aspartate transmembrane transport 1/445 11/18722 0.232553155035878 0.495961323414152 SLC1A6 1 GO:0072497 mesenchymal stem cell differentiation 1/445 11/18722 0.232553155035878 0.495961323414152 CTNNB1 1 GO:0075522 IRES-dependent viral translational initiation 1/445 11/18722 0.232553155035878 0.495961323414152 DENR 1 GO:0090160 Golgi to lysosome transport 1/445 11/18722 0.232553155035878 0.495961323414152 LAPTM5 1 GO:0090178 regulation of establishment of planar polarity involved in neural tube closure 1/445 11/18722 0.232553155035878 0.495961323414152 SFRP1 1 GO:0090394 negative regulation of excitatory postsynaptic potential 1/445 11/18722 0.232553155035878 0.495961323414152 EIF4A3 1 GO:0097050 type B pancreatic cell apoptotic process 1/445 11/18722 0.232553155035878 0.495961323414152 TCF7L2 1 GO:0097354 prenylation 1/445 11/18722 0.232553155035878 0.495961323414152 CHML 1 GO:1900112 regulation of histone H3-K9 trimethylation 1/445 11/18722 0.232553155035878 0.495961323414152 SMARCB1 1 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction 1/445 11/18722 0.232553155035878 0.495961323414152 SRI 1 GO:1903897 regulation of PERK-mediated unfolded protein response 1/445 11/18722 0.232553155035878 0.495961323414152 PPP1R15A 1 GO:1904321 response to forskolin 1/445 11/18722 0.232553155035878 0.495961323414152 FDX1 1 GO:1904322 cellular response to forskolin 1/445 11/18722 0.232553155035878 0.495961323414152 FDX1 1 GO:1904869 regulation of protein localization to Cajal body 1/445 11/18722 0.232553155035878 0.495961323414152 CCT6A 1 GO:1904871 positive regulation of protein localization to Cajal body 1/445 11/18722 0.232553155035878 0.495961323414152 CCT6A 1 GO:1905668 positive regulation of protein localization to endosome 1/445 11/18722 0.232553155035878 0.495961323414152 RDX 1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin 1/445 11/18722 0.232553155035878 0.495961323414152 TJP1 1 GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 1/445 11/18722 0.232553155035878 0.495961323414152 CD74 1 GO:0007623 circadian rhythm 7/445 210/18722 0.233919809622893 0.498618541564587 JUND/JUN/NFIL3/PPARG/HNRNPR/ATF4/NRIP1 7 GO:0015850 organic hydroxy compound transport 9/445 284/18722 0.235857000627145 0.502488535116419 APOE/APOC1/LIMA1/SLC16A3/SPP1/RXRA/TMF1/OSBPL1A/PPARG 9 GO:0001941 postsynaptic membrane organization 2/445 39/18722 0.237024051374218 0.503417149731052 APOE/ZMYND8 2 GO:0032506 cytokinetic process 2/445 39/18722 0.237024051374218 0.503417149731052 CHMP5/RHOA 2 GO:0032728 positive regulation of interferon-beta production 2/445 39/18722 0.237024051374218 0.503417149731052 RIOK3/IRF1 2 GO:0046621 negative regulation of organ growth 2/445 39/18722 0.237024051374218 0.503417149731052 STK3/CGA 2 GO:0086091 regulation of heart rate by cardiac conduction 2/445 39/18722 0.237024051374218 0.503417149731052 PKP2/DSP 2 GO:2000249 regulation of actin cytoskeleton reorganization 2/445 39/18722 0.237024051374218 0.503417149731052 HAX1/TJP1 2 GO:0000281 mitotic cytokinesis 3/445 71/18722 0.238322568216372 0.505174926247 RHOB/CHMP5/RHOA 3 GO:0072078 nephron tubule morphogenesis 3/445 71/18722 0.238322568216372 0.505174926247 CTNNB1/IRX2/GATA3 3 GO:0000041 transition metal ion transport 4/445 105/18722 0.239874595011093 0.505174926247 FTL/SLC25A37/TMEM165/SLC40A1 4 GO:0007292 female gamete generation 5/445 140/18722 0.240475075682571 0.505174926247 CTNNB1/ADAMTS1/YTHDC1/HPGD/NRIP1 5 GO:0015748 organophosphate ester transport 5/445 140/18722 0.240475075682571 0.505174926247 APOE/APOC1/SLC25A24/PLSCR1/DBI 5 GO:0050768 negative regulation of neurogenesis 5/445 140/18722 0.240475075682571 0.505174926247 WNT7A/CTNNB1/SPP1/SEMA4C/CTNNA1 5 GO:0008544 epidermis development 10/445 324/18722 0.243789394301864 0.505174926247 KLF4/CTNNB1/HLA-DRB1/ANXA1/GRHL1/YBX1/CST6/TXNIP/COL17A1/DSP 10 GO:0001736 establishment of planar polarity 3/445 72/18722 0.244677383000522 0.505174926247 WNT7A/SFRP1/RHOA 3 GO:0007164 establishment of tissue polarity 3/445 72/18722 0.244677383000522 0.505174926247 WNT7A/SFRP1/RHOA 3 GO:0030032 lamellipodium assembly 3/445 72/18722 0.244677383000522 0.505174926247 VAV2/PIK3CA/GOLPH3 3 GO:0042246 tissue regeneration 3/445 72/18722 0.244677383000522 0.505174926247 WNT7A/ANXA1/KLF5 3 GO:0043903 regulation of biological process involved in symbiotic interaction 3/445 72/18722 0.244677383000522 0.505174926247 CD74/HLA-DRB1/GSN 3 GO:1903036 positive regulation of response to wounding 3/445 72/18722 0.244677383000522 0.505174926247 ANXA1/FERMT2/PLPP3 3 GO:0016241 regulation of macroautophagy 5/445 141/18722 0.24489887938334 0.505174926247 BNIP3/HMOX1/BNIP3L/SMG1/PIK3CA 5 GO:0030183 B cell differentiation 5/445 141/18722 0.24489887938334 0.505174926247 SFRP1/INHA/KLF6/TPD52/PLCL2 5 GO:0048284 organelle fusion 5/445 141/18722 0.24489887938334 0.505174926247 ANXA1/BNIP3/SAMD9/RAB8B/VAMP8 5 GO:0050921 positive regulation of chemotaxis 5/445 141/18722 0.24489887938334 0.505174926247 CD74/TMSB4X/WNK1/AIF1/CALR 5 GO:0002062 chondrocyte differentiation 4/445 106/18722 0.24502867731905 0.505174926247 OSR2/WNT7A/CTNNB1/EFEMP1 4 GO:0006906 vesicle fusion 4/445 106/18722 0.24502867731905 0.505174926247 ANXA1/SAMD9/RAB8B/VAMP8 4 GO:0046620 regulation of organ growth 4/445 106/18722 0.24502867731905 0.505174926247 STK3/CGA/PIM1/BASP1 4 GO:0090263 positive regulation of canonical Wnt signaling pathway 4/445 106/18722 0.24502867731905 0.505174926247 SFRP1/RPS12/SOX4/WNK1 4 GO:0051302 regulation of cell division 6/445 177/18722 0.245794832342762 0.505174926247 PRPF40A/YBX1/PLK2/TXNIP/LBH/RHOA 6 GO:0098739 import across plasma membrane 6/445 177/18722 0.245794832342762 0.505174926247 SLC2A3/SLC7A1/LRP2/WNK1/SLC1A6/SLC7A5 6 GO:0006730 one-carbon metabolic process 2/445 40/18722 0.24586492181214 0.505174926247 MTHFD1L/CA2 2 GO:0010543 regulation of platelet activation 2/445 40/18722 0.24586492181214 0.505174926247 APOE/FCER1G 2 GO:0030501 positive regulation of bone mineralization 2/445 40/18722 0.24586492181214 0.505174926247 OSR2/FBN2 2 GO:0030866 cortical actin cytoskeleton organization 2/445 40/18722 0.24586492181214 0.505174926247 CALR/FMNL2 2 GO:0035329 hippo signaling 2/445 40/18722 0.24586492181214 0.505174926247 STK3/WWTR1 2 GO:0072210 metanephric nephron development 2/445 40/18722 0.24586492181214 0.505174926247 CTNNB1/IRX2 2 GO:1901998 toxin transport 2/445 40/18722 0.24586492181214 0.505174926247 BNIP3/DNAJA1 2 GO:1902686 mitochondrial outer membrane permeabilization involved in programmed cell death 2/445 40/18722 0.24586492181214 0.505174926247 BNIP3/BNIP3L 2 GO:1904994 regulation of leukocyte adhesion to vascular endothelial cell 2/445 40/18722 0.24586492181214 0.505174926247 KLF4/RHOA 2 GO:2000142 regulation of DNA-templated transcription, initiation 2/445 40/18722 0.24586492181214 0.505174926247 MED4/JUN 2 GO:0007009 plasma membrane organization 5/445 142/18722 0.249344030534102 0.505174926247 S100A9/GSN/NDRG1/PLSCR1/MYOF 5 GO:0072006 nephron development 5/445 142/18722 0.249344030534102 0.505174926247 CTNNB1/BASP1/IRX2/WWTR1/GATA3 5 GO:0035265 organ growth 6/445 178/18722 0.249742930654496 0.505174926247 STK3/CGA/PIM1/BASP1/IER3IP1/PSAP 6 GO:0048015 phosphatidylinositol-mediated signaling 6/445 178/18722 0.249742930654496 0.505174926247 KLF4/HAX1/CBL/PIK3CA/PLCL2/GATA3 6 GO:0000491 small nucleolar ribonucleoprotein complex assembly 1/445 12/18722 0.250805191057953 0.505174926247 ZNHIT6 1 GO:0001821 histamine secretion 1/445 12/18722 0.250805191057953 0.505174926247 VAMP8 1 GO:0001976 nervous system process involved in regulation of systemic arterial blood pressure 1/445 12/18722 0.250805191057953 0.505174926247 NAV2 1 GO:0002328 pro-B cell differentiation 1/445 12/18722 0.250805191057953 0.505174926247 SOX4 1 GO:0002664 regulation of T cell tolerance induction 1/445 12/18722 0.250805191057953 0.505174926247 HLA-B 1 GO:0002674 negative regulation of acute inflammatory response 1/445 12/18722 0.250805191057953 0.505174926247 GSTP1 1 GO:0002903 negative regulation of B cell apoptotic process 1/445 12/18722 0.250805191057953 0.505174926247 CD74 1 GO:0003207 cardiac chamber formation 1/445 12/18722 0.250805191057953 0.505174926247 SOX4 1 GO:0003306 Wnt signaling pathway involved in heart development 1/445 12/18722 0.250805191057953 0.505174926247 CTNNB1 1 GO:0006216 cytidine catabolic process 1/445 12/18722 0.250805191057953 0.505174926247 CDA 1 GO:0006703 estrogen biosynthetic process 1/445 12/18722 0.250805191057953 0.505174926247 HSD17B1 1 GO:0006787 porphyrin-containing compound catabolic process 1/445 12/18722 0.250805191057953 0.505174926247 HMOX1 1 GO:0007614 short-term memory 1/445 12/18722 0.250805191057953 0.505174926247 SERPINF1 1 GO:0009972 cytidine deamination 1/445 12/18722 0.250805191057953 0.505174926247 CDA 1 GO:0010459 negative regulation of heart rate 1/445 12/18722 0.250805191057953 0.505174926247 SRI 1 GO:0014889 muscle atrophy 1/445 12/18722 0.250805191057953 0.505174926247 GSN 1 GO:0021527 spinal cord association neuron differentiation 1/445 12/18722 0.250805191057953 0.505174926247 LMO4 1 GO:0021781 glial cell fate commitment 1/445 12/18722 0.250805191057953 0.505174926247 CTNNB1 1 GO:0030157 pancreatic juice secretion 1/445 12/18722 0.250805191057953 0.505174926247 WNK1 1 GO:0032536 regulation of cell projection size 1/445 12/18722 0.250805191057953 0.505174926247 WNT7A 1 GO:0032736 positive regulation of interleukin-13 production 1/445 12/18722 0.250805191057953 0.505174926247 GATA3 1 GO:0032908 regulation of transforming growth factor beta1 production 1/445 12/18722 0.250805191057953 0.505174926247 TYROBP 1 GO:0033004 negative regulation of mast cell activation 1/445 12/18722 0.250805191057953 0.505174926247 HMOX1 1 GO:0033015 tetrapyrrole catabolic process 1/445 12/18722 0.250805191057953 0.505174926247 HMOX1 1 GO:0033235 positive regulation of protein sumoylation 1/445 12/18722 0.250805191057953 0.505174926247 GNL3 1 GO:0033629 negative regulation of cell adhesion mediated by integrin 1/445 12/18722 0.250805191057953 0.505174926247 WNK1 1 GO:0034370 triglyceride-rich lipoprotein particle remodeling 1/445 12/18722 0.250805191057953 0.505174926247 APOE 1 GO:0034372 very-low-density lipoprotein particle remodeling 1/445 12/18722 0.250805191057953 0.505174926247 APOE 1 GO:0035112 genitalia morphogenesis 1/445 12/18722 0.250805191057953 0.505174926247 CTNNB1 1 GO:0038203 TORC2 signaling 1/445 12/18722 0.250805191057953 0.505174926247 MAPKAP1 1 GO:0043129 surfactant homeostasis 1/445 12/18722 0.250805191057953 0.505174926247 LPCAT1 1 GO:0043301 negative regulation of leukocyte degranulation 1/445 12/18722 0.250805191057953 0.505174926247 HMOX1 1 GO:0043383 negative T cell selection 1/445 12/18722 0.250805191057953 0.505174926247 CD74 1 GO:0043476 pigment accumulation 1/445 12/18722 0.250805191057953 0.505174926247 CD63 1 GO:0043482 cellular pigment accumulation 1/445 12/18722 0.250805191057953 0.505174926247 CD63 1 GO:0044650 adhesion of symbiont to host cell 1/445 12/18722 0.250805191057953 0.505174926247 HSP90AB1 1 GO:0045117 azole transmembrane transport 1/445 12/18722 0.250805191057953 0.505174926247 SLC7A1 1 GO:0046087 cytidine metabolic process 1/445 12/18722 0.250805191057953 0.505174926247 CDA 1 GO:0051340 regulation of ligase activity 1/445 12/18722 0.250805191057953 0.505174926247 TMSB4X 1 GO:0060009 Sertoli cell development 1/445 12/18722 0.250805191057953 0.505174926247 FNDC3A 1 GO:0060019 radial glial cell differentiation 1/445 12/18722 0.250805191057953 0.505174926247 RHOA 1 GO:0060442 branching involved in prostate gland morphogenesis 1/445 12/18722 0.250805191057953 0.505174926247 SFRP1 1 GO:0060788 ectodermal placode formation 1/445 12/18722 0.250805191057953 0.505174926247 CTNNB1 1 GO:0070202 regulation of establishment of protein localization to chromosome 1/445 12/18722 0.250805191057953 0.505174926247 CCT6A 1 GO:0070493 thrombin-activated receptor signaling pathway 1/445 12/18722 0.250805191057953 0.505174926247 HPGD 1 GO:0071697 ectodermal placode morphogenesis 1/445 12/18722 0.250805191057953 0.505174926247 CTNNB1 1 GO:0072520 seminiferous tubule development 1/445 12/18722 0.250805191057953 0.505174926247 ING2 1 GO:0090177 establishment of planar polarity involved in neural tube closure 1/445 12/18722 0.250805191057953 0.505174926247 SFRP1 1 GO:0090557 establishment of endothelial intestinal barrier 1/445 12/18722 0.250805191057953 0.505174926247 TJP1 1 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress 1/445 12/18722 0.250805191057953 0.505174926247 JUN 1 GO:0140289 protein mono-ADP-ribosylation 1/445 12/18722 0.250805191057953 0.505174926247 PARP14 1 GO:1901298 regulation of hydrogen peroxide-mediated programmed cell death 1/445 12/18722 0.250805191057953 0.505174926247 PAWR 1 GO:1901894 regulation of ATPase-coupled calcium transmembrane transporter activity 1/445 12/18722 0.250805191057953 0.505174926247 HSPA2 1 GO:1903405 protein localization to nuclear body 1/445 12/18722 0.250805191057953 0.505174926247 CCT6A 1 GO:1903599 positive regulation of autophagy of mitochondrion 1/445 12/18722 0.250805191057953 0.505174926247 BNIP3 1 GO:1903909 regulation of receptor clustering 1/445 12/18722 0.250805191057953 0.505174926247 GSN 1 GO:1904867 protein localization to Cajal body 1/445 12/18722 0.250805191057953 0.505174926247 CCT6A 1 GO:1904953 Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation 1/445 12/18722 0.250805191057953 0.505174926247 CTNNB1 1 GO:1905214 regulation of RNA binding 1/445 12/18722 0.250805191057953 0.505174926247 EIF4A3 1 GO:1905666 regulation of protein localization to endosome 1/445 12/18722 0.250805191057953 0.505174926247 RDX 1 GO:1905709 negative regulation of membrane permeability 1/445 12/18722 0.250805191057953 0.505174926247 BNIP3 1 GO:2000009 negative regulation of protein localization to cell surface 1/445 12/18722 0.250805191057953 0.505174926247 GOPC 1 GO:2000035 regulation of stem cell division 1/445 12/18722 0.250805191057953 0.505174926247 LBH 1 GO:2000508 regulation of dendritic cell chemotaxis 1/445 12/18722 0.250805191057953 0.505174926247 CALR 1 GO:2001204 regulation of osteoclast development 1/445 12/18722 0.250805191057953 0.505174926247 TYROBP 1 GO:0035924 cellular response to vascular endothelial growth factor stimulus 3/445 73/18722 0.251058853445919 0.505174926247 ANXA1/CD63/PIK3CA 3 GO:0043299 leukocyte degranulation 3/445 73/18722 0.251058853445919 0.505174926247 HMOX1/CBL/VAMP8 3 GO:0050848 regulation of calcium-mediated signaling 3/445 73/18722 0.251058853445919 0.505174926247 FHL2/GBP1/CAMTA1 3 GO:0051298 centrosome duplication 3/445 73/18722 0.251058853445919 0.505174926247 CENPJ/CHMP5/PLK2 3 GO:0072088 nephron epithelium morphogenesis 3/445 73/18722 0.251058853445919 0.505174926247 CTNNB1/IRX2/GATA3 3 GO:0072089 stem cell proliferation 3/445 73/18722 0.251058853445919 0.505174926247 PIM1/EIF2AK2/FERMT2 3 GO:0010951 negative regulation of endopeptidase activity 8/445 252/18722 0.251946998936143 0.506468638737326 KLF4/SPINT1/TNFAIP8/PAK2/CST6/BIRC7/SERPINF1/CST3 8 GO:0090257 regulation of muscle system process 8/445 252/18722 0.251946998936143 0.506468638737326 TPM1/KLF4/TNNI2/SRI/PKP2/AIF1/DSP/RHOA 8 GO:0001936 regulation of endothelial cell proliferation 6/445 179/18722 0.253708969542241 0.509221905889172 APOE/HMOX1/PPARG/RGCC/SPARC/PDCD6 6 GO:1901991 negative regulation of mitotic cell cycle phase transition 6/445 179/18722 0.253708969542241 0.509221905889172 KLF4/SOX4/PLK2/BRD7/RGCC/WEE1 6 GO:0031023 microtubule organizing center organization 5/445 143/18722 0.253809708115663 0.509221905889172 CTNNB1/CENPJ/GOLGA2/CHMP5/PLK2 5 GO:0070555 response to interleukin-1 5/445 143/18722 0.253809708115663 0.509221905889172 CEBPB/SFRP1/ANXA1/AKAP12/GBP1 5 GO:0007099 centriole replication 2/445 41/18722 0.254717465240327 0.509558280342755 CENPJ/PLK2 2 GO:0031062 positive regulation of histone methylation 2/445 41/18722 0.254717465240327 0.509558280342755 CTNNB1/RTF1 2 GO:0032735 positive regulation of interleukin-12 production 2/445 41/18722 0.254717465240327 0.509558280342755 IRF1/LAPTM5 2 GO:0042307 positive regulation of protein import into nucleus 2/445 41/18722 0.254717465240327 0.509558280342755 NUTF2/HSP90AB1 2 GO:0071634 regulation of transforming growth factor beta production 2/445 41/18722 0.254717465240327 0.509558280342755 TYROBP/HSP90AB1 2 GO:1902116 negative regulation of organelle assembly 2/445 41/18722 0.254717465240327 0.509558280342755 ODF2L/MAP4 2 GO:0060828 regulation of canonical Wnt signaling pathway 8/445 253/18722 0.255267814723882 0.510412072906272 APOE/STK3/SFRP1/RPS12/SOX4/WNK1/WWTR1/TCF7L2 8 GO:0022037 metencephalon development 4/445 108/18722 0.255408933620187 0.510447172126267 WNT7A/SEMA4C/UQCRQ/AIF1 4 GO:0051960 regulation of nervous system development 13/445 443/18722 0.257364979328168 0.512004169791563 SKIL/WNT7A/CTNNB1/SPINT1/SPP1/SEMA4C/SHTN1/GOLGA4/LRP2/UBE2V2/SERPINF1/MACF1/CTNNA1 13 GO:0002437 inflammatory response to antigenic stimulus 3/445 74/18722 0.257464575887822 0.512004169791563 HLA-DRB1/PLK2/GATA3 3 GO:0007040 lysosome organization 3/445 74/18722 0.257464575887822 0.512004169791563 CHMP5/TMEM165/LAPTM5 3 GO:0080171 lytic vacuole organization 3/445 74/18722 0.257464575887822 0.512004169791563 CHMP5/TMEM165/LAPTM5 3 GO:0010721 negative regulation of cell development 6/445 180/18722 0.257692382149611 0.512004169791563 WNT7A/CTNNB1/SPP1/SEMA4C/CTNNA1/GBP1 6 GO:0071897 DNA biosynthetic process 6/445 180/18722 0.257692382149611 0.512004169791563 KLF4/CTNNB1/HSP90AB1/HNRNPA1/CCT6A/RGCC 6 GO:0007612 learning 5/445 144/18722 0.258295091887403 0.512004169791563 FOS/JUN/UBA6/EIF2AK4/EIF4A3 5 GO:0010821 regulation of mitochondrion organization 5/445 144/18722 0.258295091887403 0.512004169791563 HAX1/BNIP3/BNIP3L/PPARG/GOLPH3 5 GO:0014065 phosphatidylinositol 3-kinase signaling 5/445 144/18722 0.258295091887403 0.512004169791563 KLF4/HAX1/CBL/PIK3CA/GATA3 5 GO:0006479 protein methylation 6/445 181/18722 0.26169260074758 0.512004169791563 CTNNB1/IWS1/SMARCB1/KMT2C/RTF1/GATA3 6 GO:0008213 protein alkylation 6/445 181/18722 0.26169260074758 0.512004169791563 CTNNB1/IWS1/SMARCB1/KMT2C/RTF1/GATA3 6 GO:0097696 receptor signaling pathway via STAT 6/445 181/18722 0.26169260074758 0.512004169791563 IFNAR1/CENPJ/PARP14/JAK1/PPARG/CSH1 6 GO:0006338 chromatin remodeling 8/445 255/18722 0.261950175755151 0.512004169791563 TSPYL2/CBX3/BRD2/SMARCB1/SPTY2D1/MBD2/RSF1/GATA3 8 GO:0046700 heterocycle catabolic process 13/445 445/18722 0.262396062507832 0.512004169791563 DFFB/VIM/HMOX1/PKP3/MEX3D/SMG1/HNRNPM/YBX1/EIF4A3/HSPA1B/SERBP1/HNRNPR/CDA 13 GO:0051961 negative regulation of nervous system development 5/445 145/18722 0.262799362792568 0.512004169791563 WNT7A/CTNNB1/SPP1/SEMA4C/CTNNA1 5 GO:0034655 nucleobase-containing compound catabolic process 12/445 407/18722 0.263396112117782 0.512004169791563 DFFB/VIM/PKP3/MEX3D/SMG1/HNRNPM/YBX1/EIF4A3/HSPA1B/SERBP1/HNRNPR/CDA 12 GO:0000266 mitochondrial fission 2/445 42/18722 0.263576145408377 0.512004169791563 BNIP3/PPARG 2 GO:0016601 Rac protein signal transduction 2/445 42/18722 0.263576145408377 0.512004169791563 GABARAP/AIF1 2 GO:0021795 cerebral cortex cell migration 2/445 42/18722 0.263576145408377 0.512004169791563 CTNNB1/RHOA 2 GO:0032965 regulation of collagen biosynthetic process 2/445 42/18722 0.263576145408377 0.512004169791563 VIM/RGCC 2 GO:0043507 positive regulation of JUN kinase activity 2/445 42/18722 0.263576145408377 0.512004169791563 ARHGEF5/SASH1 2 GO:0048489 synaptic vesicle transport 2/445 42/18722 0.263576145408377 0.512004169791563 AP3S1/CTNNB1 2 GO:0051602 response to electrical stimulus 2/445 42/18722 0.263576145408377 0.512004169791563 AIF1/AKAP12 2 GO:0055090 acylglycerol homeostasis 2/445 42/18722 0.263576145408377 0.512004169791563 APOE/ANGPTL4 2 GO:0070328 triglyceride homeostasis 2/445 42/18722 0.263576145408377 0.512004169791563 APOE/ANGPTL4 2 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis 2/445 42/18722 0.263576145408377 0.512004169791563 KLF4/RHOA 2 GO:0090317 negative regulation of intracellular protein transport 2/445 42/18722 0.263576145408377 0.512004169791563 SP100/UBE2J1 2 GO:1904037 positive regulation of epithelial cell apoptotic process 2/445 42/18722 0.263576145408377 0.512004169791563 GSN/RGCC 2 GO:0033077 T cell differentiation in thymus 3/445 75/18722 0.26389218737246 0.512004169791563 CD74/CTNNB1/GATA3 3 GO:0061333 renal tubule morphogenesis 3/445 75/18722 0.26389218737246 0.512004169791563 CTNNB1/IRX2/GATA3 3 GO:1903363 negative regulation of cellular protein catabolic process 3/445 75/18722 0.26389218737246 0.512004169791563 RYBP/RPL23/HSP90AB1 3 GO:0003002 regionalization 10/445 331/18722 0.264123685214029 0.512004169791563 WNT7A/SFRP1/CTNNB1/AIDA/BASP1/LRP2/IRX2/TMEM107/C1QA/ETS2 10 GO:0090596 sensory organ morphogenesis 8/445 256/18722 0.265311073540911 0.512004169791563 OSR2/FBN2/CTNNB1/THRB/HMGN1/EFEMP1/ATF4/GATA3 8 GO:0048017 inositol lipid-mediated signaling 6/445 182/18722 0.265709056976017 0.512004169791563 KLF4/HAX1/CBL/PIK3CA/PLCL2/GATA3 6 GO:0090174 organelle membrane fusion 4/445 110/18722 0.265876643095543 0.512004169791563 ANXA1/SAMD9/RAB8B/VAMP8 4 GO:0034764 positive regulation of transmembrane transport 7/445 219/18722 0.266215171089981 0.512004169791563 CA2/TMSB4X/SRI/HSPA2/WNK1/CTSS/NDUFA4 7 GO:2001020 regulation of response to DNA damage stimulus 7/445 219/18722 0.266215171089981 0.512004169791563 CD74/SKIL/ING2/UBE2V1/SMG1/UBE2V2/MCL1 7 GO:0001768 establishment of T cell polarity 1/445 13/18722 0.268624094851604 0.512004169791563 GSN 1 GO:0001778 plasma membrane repair 1/445 13/18722 0.268624094851604 0.512004169791563 MYOF 1 GO:0001833 inner cell mass cell proliferation 1/445 13/18722 0.268624094851604 0.512004169791563 SBDS 1 GO:0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis 1/445 13/18722 0.268624094851604 0.512004169791563 CTNNB1 1 GO:0006361 transcription initiation from RNA polymerase I promoter 1/445 13/18722 0.268624094851604 0.512004169791563 SMARCB1 1 GO:0006995 cellular response to nitrogen starvation 1/445 13/18722 0.268624094851604 0.512004169791563 GABARAP 1 GO:0007183 SMAD protein complex assembly 1/445 13/18722 0.268624094851604 0.512004169791563 PMEPA1 1 GO:0007567 parturition 1/445 13/18722 0.268624094851604 0.512004169791563 HPGD 1 GO:0008298 intracellular mRNA localization 1/445 13/18722 0.268624094851604 0.512004169791563 MEX3D 1 GO:0010635 regulation of mitochondrial fusion 1/445 13/18722 0.268624094851604 0.512004169791563 BNIP3 1 GO:0010745 negative regulation of macrophage derived foam cell differentiation 1/445 13/18722 0.268624094851604 0.512004169791563 PPARG 1 GO:0014745 negative regulation of muscle adaptation 1/445 13/18722 0.268624094851604 0.512004169791563 KLF4 1 GO:0015809 arginine transport 1/445 13/18722 0.268624094851604 0.512004169791563 SLC7A1 1 GO:0016322 neuron remodeling 1/445 13/18722 0.268624094851604 0.512004169791563 C1QA 1 GO:0019755 one-carbon compound transport 1/445 13/18722 0.268624094851604 0.512004169791563 CA2 1 GO:0021514 ventral spinal cord interneuron differentiation 1/445 13/18722 0.268624094851604 0.512004169791563 LMO4 1 GO:0021554 optic nerve development 1/445 13/18722 0.268624094851604 0.512004169791563 NAV2 1 GO:0021681 cerebellar granular layer development 1/445 13/18722 0.268624094851604 0.512004169791563 WNT7A 1 GO:0021794 thalamus development 1/445 13/18722 0.268624094851604 0.512004169791563 UQCRQ 1 GO:0021819 layer formation in cerebral cortex 1/445 13/18722 0.268624094851604 0.512004169791563 CTNNB1 1 GO:0021859 pyramidal neuron differentiation 1/445 13/18722 0.268624094851604 0.512004169791563 UQCRQ 1 GO:0030836 positive regulation of actin filament depolymerization 1/445 13/18722 0.268624094851604 0.512004169791563 DSTN 1 GO:0031272 regulation of pseudopodium assembly 1/445 13/18722 0.268624094851604 0.512004169791563 CDC42EP3 1 GO:0031274 positive regulation of pseudopodium assembly 1/445 13/18722 0.268624094851604 0.512004169791563 CDC42EP3 1 GO:0032252 secretory granule localization 1/445 13/18722 0.268624094851604 0.512004169791563 TANC2 1 GO:0032352 positive regulation of hormone metabolic process 1/445 13/18722 0.268624094851604 0.512004169791563 GATA3 1 GO:0032429 regulation of phospholipase A2 activity 1/445 13/18722 0.268624094851604 0.512004169791563 ANXA1 1 GO:0032530 regulation of microvillus organization 1/445 13/18722 0.268624094851604 0.512004169791563 KLF5 1 GO:0032905 transforming growth factor beta1 production 1/445 13/18722 0.268624094851604 0.512004169791563 TYROBP 1 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter 1/445 13/18722 0.268624094851604 0.512004169791563 CTNNB1 1 GO:0034112 positive regulation of homotypic cell-cell adhesion 1/445 13/18722 0.268624094851604 0.512004169791563 JAK1 1 GO:0035745 T-helper 2 cell cytokine production 1/445 13/18722 0.268624094851604 0.512004169791563 GATA3 1 GO:0042492 gamma-delta T cell differentiation 1/445 13/18722 0.268624094851604 0.512004169791563 SOX4 1 GO:0042659 regulation of cell fate specification 1/445 13/18722 0.268624094851604 0.512004169791563 LMO4 1 GO:0043562 cellular response to nitrogen levels 1/445 13/18722 0.268624094851604 0.512004169791563 GABARAP 1 GO:0044794 positive regulation by host of viral process 1/445 13/18722 0.268624094851604 0.512004169791563 APOE 1 GO:0048207 vesicle targeting, rough ER to cis-Golgi 1/445 13/18722 0.268624094851604 0.512004169791563 PDCD6 1 GO:0048208 COPII vesicle coating 1/445 13/18722 0.268624094851604 0.512004169791563 PDCD6 1 GO:0048820 hair follicle maturation 1/445 13/18722 0.268624094851604 0.512004169791563 CTNNB1 1 GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 1/445 13/18722 0.268624094851604 0.512004169791563 SRI 1 GO:0060340 positive regulation of type I interferon-mediated signaling pathway 1/445 13/18722 0.268624094851604 0.512004169791563 LSM14A 1 GO:0061000 negative regulation of dendritic spine development 1/445 13/18722 0.268624094851604 0.512004169791563 PLK2 1 GO:0061469 regulation of type B pancreatic cell proliferation 1/445 13/18722 0.268624094851604 0.512004169791563 SFRP1 1 GO:0070254 mucus secretion 1/445 13/18722 0.268624094851604 0.512004169791563 VAMP8 1 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway 1/445 13/18722 0.268624094851604 0.512004169791563 HSPA1B 1 GO:0071696 ectodermal placode development 1/445 13/18722 0.268624094851604 0.512004169791563 CTNNB1 1 GO:0072578 neurotransmitter-gated ion channel clustering 1/445 13/18722 0.268624094851604 0.512004169791563 APOE 1 GO:0090042 tubulin deacetylation 1/445 13/18722 0.268624094851604 0.512004169791563 BEX4 1 GO:1900044 regulation of protein K63-linked ubiquitination 1/445 13/18722 0.268624094851604 0.512004169791563 SASH1 1 GO:1900115 extracellular regulation of signal transduction 1/445 13/18722 0.268624094851604 0.512004169791563 FBN2 1 GO:1900116 extracellular negative regulation of signal transduction 1/445 13/18722 0.268624094851604 0.512004169791563 FBN2 1 GO:1902947 regulation of tau-protein kinase activity 1/445 13/18722 0.268624094851604 0.512004169791563 HSP90AB1 1 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding 1/445 13/18722 0.268624094851604 0.512004169791563 TMSB4X 1 GO:1903054 negative regulation of extracellular matrix organization 1/445 13/18722 0.268624094851604 0.512004169791563 CST3 1 GO:1903651 positive regulation of cytoplasmic transport 1/445 13/18722 0.268624094851604 0.512004169791563 RDX 1 GO:1904925 positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization 1/445 13/18722 0.268624094851604 0.512004169791563 CDC37 1 GO:1904995 negative regulation of leukocyte adhesion to vascular endothelial cell 1/445 13/18722 0.268624094851604 0.512004169791563 KLF4 1 GO:1905244 regulation of modification of synaptic structure 1/445 13/18722 0.268624094851604 0.512004169791563 RHOA 1 GO:1905907 negative regulation of amyloid fibril formation 1/445 13/18722 0.268624094851604 0.512004169791563 APOE 1 GO:1990403 embryonic brain development 1/445 13/18722 0.268624094851604 0.512004169791563 CTNNB1 1 GO:2000318 positive regulation of T-helper 17 type immune response 1/445 13/18722 0.268624094851604 0.512004169791563 NFKBIZ 1 GO:2000551 regulation of T-helper 2 cell cytokine production 1/445 13/18722 0.268624094851604 0.512004169791563 GATA3 1 GO:2001023 regulation of response to drug 1/445 13/18722 0.268624094851604 0.512004169791563 ADIRF 1 GO:0006325 chromatin organization 12/445 409/18722 0.268706134134134 0.512004169791563 TSPYL2/ING2/CBX3/BRD2/SMARCB1/SPTY2D1/SAFB/ARID4B/HMGN1/MBD2/RSF1/GATA3 12 GO:0006305 DNA alkylation 3/445 76/18722 0.270339366455833 0.513930935494268 FOS/MBD2/PIK3CA 3 GO:0006306 DNA methylation 3/445 76/18722 0.270339366455833 0.513930935494268 FOS/MBD2/PIK3CA 3 GO:0072028 nephron morphogenesis 3/445 76/18722 0.270339366455833 0.513930935494268 CTNNB1/IRX2/GATA3 3 GO:0140029 exocytic process 3/445 76/18722 0.270339366455833 0.513930935494268 CTBP2/RAB8B/VAMP8 3 GO:2000379 positive regulation of reactive oxygen species metabolic process 3/445 76/18722 0.270339366455833 0.513930935494268 TYROBP/GSTP1/GRB2 3 GO:1902652 secondary alcohol metabolic process 5/445 147/18722 0.271861298055052 0.51577992681825 APOE/LIMA1/RXRA/FDX1/OSBPL1A 5 GO:0002861 regulation of inflammatory response to antigenic stimulus 2/445 43/18722 0.272435681509906 0.51577992681825 HLA-DRB1/PLK2 2 GO:0033173 calcineurin-NFAT signaling cascade 2/445 43/18722 0.272435681509906 0.51577992681825 FHL2/CAMTA1 2 GO:0035794 positive regulation of mitochondrial membrane permeability 2/445 43/18722 0.272435681509906 0.51577992681825 BNIP3/BNIP3L 2 GO:0036230 granulocyte activation 2/445 43/18722 0.272435681509906 0.51577992681825 TYROBP/FCER1G 2 GO:0042088 T-helper 1 type immune response 2/445 43/18722 0.272435681509906 0.51577992681825 HLA-DRB1/ANXA1 2 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 2/445 43/18722 0.272435681509906 0.51577992681825 CD74/ING2 2 GO:0071604 transforming growth factor beta production 2/445 43/18722 0.272435681509906 0.51577992681825 TYROBP/HSP90AB1 2 GO:0140353 lipid export from cell 2/445 43/18722 0.272435681509906 0.51577992681825 SPP1/TMF1 2 GO:0071219 cellular response to molecule of bacterial origin 7/445 221/18722 0.27355645600479 0.517664553255056 CEBPB/VIM/LITAF/GSTP1/SASH1/CHMP5/RHOA 7 GO:0070507 regulation of microtubule cytoskeleton organization 5/445 148/18722 0.276417333721391 0.522135451086991 CCSAP/RASSF7/CHMP5/HSPA1B/RHOA 5 GO:0097530 granulocyte migration 5/445 148/18722 0.276417333721391 0.522135451086991 CD74/S100A9/ANXA1/S100A8/FCER1G 5 GO:0048640 negative regulation of developmental growth 4/445 112/18722 0.276421528407105 0.522135451086991 STK3/CGA/SPP1/SEMA4C 4 GO:0007492 endoderm development 3/445 77/18722 0.276803833909589 0.522135451086991 CTNNB1/DUSP4/RTF1 3 GO:0032418 lysosome localization 3/445 77/18722 0.276803833909589 0.522135451086991 HMOX1/CBL/VAMP8 3 GO:0055117 regulation of cardiac muscle contraction 3/445 77/18722 0.276803833909589 0.522135451086991 SRI/PKP2/DSP 3 GO:0140056 organelle localization by membrane tethering 3/445 77/18722 0.276803833909589 0.522135451086991 CTBP2/RAB8B/VAMP8 3 GO:0044270 cellular nitrogen compound catabolic process 13/445 451/18722 0.277692049091775 0.5235042646338 DFFB/VIM/HMOX1/PKP3/MEX3D/SMG1/HNRNPM/YBX1/EIF4A3/HSPA1B/SERBP1/HNRNPR/CDA 13 GO:1905039 carboxylic acid transmembrane transport 5/445 149/18722 0.28098899987751 0.5235042646338 SLC16A3/SLC7A1/LRP2/SLC1A6/SLC7A5 5 GO:0002792 negative regulation of peptide secretion 2/445 44/18722 0.281291039213543 0.5235042646338 CD74/SFRP1 2 GO:0021517 ventral spinal cord development 2/445 44/18722 0.281291039213543 0.5235042646338 SOX4/LMO4 2 GO:0042269 regulation of natural killer cell mediated cytotoxicity 2/445 44/18722 0.281291039213543 0.5235042646338 HLA-B/HLA-A 2 GO:0042554 superoxide anion generation 2/445 44/18722 0.281291039213543 0.5235042646338 TYROBP/GSTP1 2 GO:0045124 regulation of bone resorption 2/445 44/18722 0.281291039213543 0.5235042646338 CA2/SPP1 2 GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT 2/445 44/18722 0.281291039213543 0.5235042646338 CENPJ/CSH1 2 GO:0048806 genitalia development 2/445 44/18722 0.281291039213543 0.5235042646338 CTNNB1/LRP2 2 GO:0060711 labyrinthine layer development 2/445 44/18722 0.281291039213543 0.5235042646338 SPINT1/GRB2 2 GO:0097178 ruffle assembly 2/445 44/18722 0.281291039213543 0.5235042646338 AIF1/RDX 2 GO:1903214 regulation of protein targeting to mitochondrion 2/445 44/18722 0.281291039213543 0.5235042646338 HAX1/BNIP3L 2 GO:0044106 cellular amine metabolic process 4/445 113/18722 0.281719744018527 0.5235042646338 GDPD3/SAT1/AMD1/GATA3 4 GO:0071347 cellular response to interleukin-1 4/445 113/18722 0.281719744018527 0.5235042646338 CEBPB/SFRP1/AKAP12/GBP1 4 GO:0042254 ribosome biogenesis 9/445 299/18722 0.282518193466828 0.5235042646338 MPHOSPH10/ZNHIT6/RIOK3/RPS15/SBDS/RBFA/EIF4A3/RPS19/RPS28 9 GO:0009896 positive regulation of catabolic process 14/445 492/18722 0.283169397387998 0.5235042646338 APOE/LPCAT1/GABARAP/BNIP3/HMOX1/BNIP3L/MEX3D/LRP2/UBE2V2/HSPA1B/PLK2/HNRNPR/RDX/LAPTM5 14 GO:0030500 regulation of bone mineralization 3/445 78/18722 0.283283353338694 0.5235042646338 OSR2/FBN2/SRGN 3 GO:0090559 regulation of membrane permeability 3/445 78/18722 0.283283353338694 0.5235042646338 BNIP3/BNIP3L/LAPTM5 3 GO:1903825 organic acid transmembrane transport 5/445 150/18722 0.28557548910415 0.5235042646338 SLC16A3/SLC7A1/LRP2/SLC1A6/SLC7A5 5 GO:0010466 negative regulation of peptidase activity 8/445 262/18722 0.285731922923221 0.5235042646338 KLF4/SPINT1/TNFAIP8/PAK2/CST6/BIRC7/SERPINF1/CST3 8 GO:0000054 ribosomal subunit export from nucleus 1/445 14/18722 0.286020122313843 0.5235042646338 RPS15 1 GO:0000212 meiotic spindle organization 1/445 14/18722 0.286020122313843 0.5235042646338 GOLGA2 1 GO:0001767 establishment of lymphocyte polarity 1/445 14/18722 0.286020122313843 0.5235042646338 GSN 1 GO:0002517 T cell tolerance induction 1/445 14/18722 0.286020122313843 0.5235042646338 HLA-B 1 GO:0002829 negative regulation of type 2 immune response 1/445 14/18722 0.286020122313843 0.5235042646338 ANXA1 1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity 1/445 14/18722 0.286020122313843 0.5235042646338 CBL 1 GO:0010421 hydrogen peroxide-mediated programmed cell death 1/445 14/18722 0.286020122313843 0.5235042646338 PAWR 1 GO:0010457 centriole-centriole cohesion 1/445 14/18722 0.286020122313843 0.5235042646338 CTNNB1 1 GO:0010771 negative regulation of cell morphogenesis involved in differentiation 1/445 14/18722 0.286020122313843 0.5235042646338 GBP1 1 GO:0015074 DNA integration 1/445 14/18722 0.286020122313843 0.5235042646338 SMARCB1 1 GO:0030049 muscle filament sliding 1/445 14/18722 0.286020122313843 0.5235042646338 TPM1 1 GO:0033008 positive regulation of mast cell activation involved in immune response 1/445 14/18722 0.286020122313843 0.5235042646338 VAMP8 1 GO:0033750 ribosome localization 1/445 14/18722 0.286020122313843 0.5235042646338 RPS15 1 GO:0034111 negative regulation of homotypic cell-cell adhesion 1/445 14/18722 0.286020122313843 0.5235042646338 RDX 1 GO:0034616 response to laminar fluid shear stress 1/445 14/18722 0.286020122313843 0.5235042646338 KLF4 1 GO:0035641 locomotory exploration behavior 1/445 14/18722 0.286020122313843 0.5235042646338 APOE 1 GO:0035672 oligopeptide transmembrane transport 1/445 14/18722 0.286020122313843 0.5235042646338 CA2 1 GO:0038166 angiotensin-activated signaling pathway 1/445 14/18722 0.286020122313843 0.5235042646338 CA2 1 GO:0042415 norepinephrine metabolic process 1/445 14/18722 0.286020122313843 0.5235042646338 GATA3 1 GO:0042921 glucocorticoid receptor signaling pathway 1/445 14/18722 0.286020122313843 0.5235042646338 CALR 1 GO:0043306 positive regulation of mast cell degranulation 1/445 14/18722 0.286020122313843 0.5235042646338 VAMP8 1 GO:0043374 CD8-positive, alpha-beta T cell differentiation 1/445 14/18722 0.286020122313843 0.5235042646338 IRF1 1 GO:0043650 dicarboxylic acid biosynthetic process 1/445 14/18722 0.286020122313843 0.5235042646338 MTHFD1L 1 GO:0043922 negative regulation by host of viral transcription 1/445 14/18722 0.286020122313843 0.5235042646338 JUN 1 GO:0045059 positive thymic T cell selection 1/445 14/18722 0.286020122313843 0.5235042646338 CD74 1 GO:0045472 response to ether 1/445 14/18722 0.286020122313843 0.5235042646338 GOLPH3 1 GO:0046131 pyrimidine ribonucleoside metabolic process 1/445 14/18722 0.286020122313843 0.5235042646338 CDA 1 GO:0046133 pyrimidine ribonucleoside catabolic process 1/445 14/18722 0.286020122313843 0.5235042646338 CDA 1 GO:0048681 negative regulation of axon regeneration 1/445 14/18722 0.286020122313843 0.5235042646338 SPP1 1 GO:0048875 chemical homeostasis within a tissue 1/445 14/18722 0.286020122313843 0.5235042646338 LPCAT1 1 GO:0051589 negative regulation of neurotransmitter transport 1/445 14/18722 0.286020122313843 0.5235042646338 RAP1B 1 GO:0051764 actin crosslink formation 1/445 14/18722 0.286020122313843 0.5235042646338 AIF1 1 GO:0060576 intestinal epithelial cell development 1/445 14/18722 0.286020122313843 0.5235042646338 KLF5 1 GO:0071236 cellular response to antibiotic 1/445 14/18722 0.286020122313843 0.5235042646338 RPL23 1 GO:0071285 cellular response to lithium ion 1/445 14/18722 0.286020122313843 0.5235042646338 CALR 1 GO:0072176 nephric duct development 1/445 14/18722 0.286020122313843 0.5235042646338 GATA3 1 GO:0090128 regulation of synapse maturation 1/445 14/18722 0.286020122313843 0.5235042646338 YWHAZ 1 GO:0097091 synaptic vesicle clustering 1/445 14/18722 0.286020122313843 0.5235042646338 CTNNB1 1 GO:1900025 negative regulation of substrate adhesion-dependent cell spreading 1/445 14/18722 0.286020122313843 0.5235042646338 GBP1 1 GO:1901077 regulation of relaxation of muscle 1/445 14/18722 0.286020122313843 0.5235042646338 SRI 1 GO:1901722 regulation of cell proliferation involved in kidney development 1/445 14/18722 0.286020122313843 0.5235042646338 GATA3 1 GO:1901857 positive regulation of cellular respiration 1/445 14/18722 0.286020122313843 0.5235042646338 IFNAR1 1 GO:1902036 regulation of hematopoietic stem cell differentiation 1/445 14/18722 0.286020122313843 0.5235042646338 EIF2AK2 1 GO:1904152 regulation of retrograde protein transport, ER to cytosol 1/445 14/18722 0.286020122313843 0.5235042646338 UBE2J1 1 GO:1904923 regulation of autophagy of mitochondrion in response to mitochondrial depolarization 1/445 14/18722 0.286020122313843 0.5235042646338 CDC37 1 GO:1990173 protein localization to nucleoplasm 1/445 14/18722 0.286020122313843 0.5235042646338 CCT6A 1 GO:2001171 positive regulation of ATP biosynthetic process 1/445 14/18722 0.286020122313843 0.5235042646338 TMSB4X 1 GO:0007041 lysosomal transport 4/445 114/18722 0.28703347387495 0.524197736771626 RHOB/CHMP5/LAPTM5/PSAP 4 GO:0019751 polyol metabolic process 4/445 114/18722 0.28703347387495 0.524197736771626 IMPA2/ISYNA1/PTS/PLPP3 4 GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 4/445 114/18722 0.28703347387495 0.524197736771626 ING2/INHA/HSP90AB1/PPARG 4 GO:1901800 positive regulation of proteasomal protein catabolic process 4/445 114/18722 0.28703347387495 0.524197736771626 GABARAP/UBE2V2/HSPA1B/PLK2 4 GO:1904892 regulation of receptor signaling pathway via STAT 4/445 114/18722 0.28703347387495 0.524197736771626 CENPJ/PARP14/PPARG/CSH1 4 GO:0006029 proteoglycan metabolic process 3/445 79/18722 0.28977573171539 0.526908591288205 CTNNB1/HS6ST1/TCF7L2 3 GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide 3/445 79/18722 0.28977573171539 0.526908591288205 RPL39/S100A9/RPS19 3 GO:0030308 negative regulation of cell growth 6/445 188/18722 0.290116935899878 0.526908591288205 TSPYL2/SFRP1/SPP1/SEMA4C/HSPA1B/CDA 6 GO:0006903 vesicle targeting 2/445 45/18722 0.290137421974428 0.526908591288205 ARFGAP3/PDCD6 2 GO:0022602 ovulation cycle process 2/445 45/18722 0.290137421974428 0.526908591288205 ADAMTS1/NRIP1 2 GO:0035987 endodermal cell differentiation 2/445 45/18722 0.290137421974428 0.526908591288205 CTNNB1/RTF1 2 GO:0048546 digestive tract morphogenesis 2/445 45/18722 0.290137421974428 0.526908591288205 SFRP1/CTNNB1 2 GO:0051180 vitamin transport 2/445 45/18722 0.290137421974428 0.526908591288205 SLC2A3/LRP2 2 GO:0060421 positive regulation of heart growth 2/445 45/18722 0.290137421974428 0.526908591288205 PIM1/BASP1 2 GO:0098534 centriole assembly 2/445 45/18722 0.290137421974428 0.526908591288205 CENPJ/PLK2 2 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process 2/445 45/18722 0.290137421974428 0.526908591288205 BNIP3/BNIP3L 2 GO:0030902 hindbrain development 5/445 151/18722 0.290175997380941 0.526908591288205 WNT7A/CTNNB1/SEMA4C/UQCRQ/AIF1 5 GO:1904064 positive regulation of cation transmembrane transport 5/445 151/18722 0.290175997380941 0.526908591288205 TMSB4X/SRI/HSPA2/WNK1/CTSS 5 GO:0050878 regulation of body fluid levels 11/445 379/18722 0.292322455899608 0.528237156610108 APOE/VAV2/CSRP1/FCER1G/GRHL1/WNK1/PLSCR1/PIK3CA/HBB/F5/VAMP8 11 GO:0030278 regulation of ossification 4/445 115/18722 0.292361481810308 0.528237156610108 OSR2/SFRP1/FBN2/SRGN 4 GO:0043279 response to alkaloid 4/445 115/18722 0.292361481810308 0.528237156610108 FOSB/HSP90AB1/SRSF9/AIF1 4 GO:0071675 regulation of mononuclear cell migration 4/445 115/18722 0.292361481810308 0.528237156610108 WNK1/AIF1/CALR/RHOA 4 GO:0050730 regulation of peptidyl-tyrosine phosphorylation 8/445 264/18722 0.292628291136557 0.528237156610108 CD74/SFRP1/HAX1/SH3BP5/PAK2/PARP14/CBL/CSH1 8 GO:0007346 regulation of mitotic cell cycle 13/445 457/18722 0.293269607531446 0.528237156610108 KLF4/CTNNB1/ANXA1/HSPA2/TMOD3/ADAMTS1/SOX4/PLK2/AIF1/BRD7/RDX/RGCC/WEE1 13 GO:0046578 regulation of Ras protein signal transduction 6/445 189/18722 0.294231137292926 0.528237156610108 APOE/GABARAP/MAPKAP1/NET1/CBL/RDX 6 GO:0016125 sterol metabolic process 5/445 152/18722 0.294789724419528 0.528237156610108 APOE/LIMA1/RXRA/FDX1/OSBPL1A 5 GO:0030509 BMP signaling pathway 5/445 152/18722 0.294789724419528 0.528237156610108 SKIL/SFRP1/UBE2D1/LRP2/PPARG 5 GO:0051092 positive regulation of NF-kappaB transcription factor activity 5/445 152/18722 0.294789724419528 0.528237156610108 S100A9/UBE2V1/S100A8/EIF2AK2/HSPA1B 5 GO:0015849 organic acid transport 9/445 303/18722 0.2953827154057 0.528237156610108 APOE/PLIN2/SLC16A3/ANXA1/SLC7A1/LRP2/SLC1A6/SLC7A5/PPARG 9 GO:0051222 positive regulation of protein transport 9/445 303/18722 0.2953827154057 0.528237156610108 ARHGEF5/HLA-DRB1/NUTF2/SRI/SOX4/HSP90AB1/IER3IP1/GOLPH3/TCF7L2 9 GO:0008286 insulin receptor signaling pathway 4/445 116/18722 0.297702543976658 0.528237156610108 AP3S1/GRB2/PIK3CA/ZNF106 4 GO:0033559 unsaturated fatty acid metabolic process 4/445 116/18722 0.297702543976658 0.528237156610108 CD74/ANXA1/GSTP1/HPGD 4 GO:0006984 ER-nucleus signaling pathway 2/445 46/18722 0.298970262617988 0.528237156610108 PPP1R15A/ATF4 2 GO:0007019 microtubule depolymerization 2/445 46/18722 0.298970262617988 0.528237156610108 CCSAP/KIF2A 2 GO:0031018 endocrine pancreas development 2/445 46/18722 0.298970262617988 0.528237156610108 ANXA1/SOX4 2 GO:0031057 negative regulation of histone modification 2/445 46/18722 0.298970262617988 0.528237156610108 TAF7/SMARCB1 2 GO:0043300 regulation of leukocyte degranulation 2/445 46/18722 0.298970262617988 0.528237156610108 HMOX1/VAMP8 2 GO:0048701 embryonic cranial skeleton morphogenesis 2/445 46/18722 0.298970262617988 0.528237156610108 MTHFD1L/EIF4A3 2 GO:0050919 negative chemotaxis 2/445 46/18722 0.298970262617988 0.528237156610108 SEMA4C/RHOA 2 GO:0071827 plasma lipoprotein particle organization 2/445 46/18722 0.298970262617988 0.528237156610108 APOE/APOC1 2 GO:0001960 negative regulation of cytokine-mediated signaling pathway 3/445 81/18722 0.302790512689139 0.528237156610108 GSTP1/PARP14/PPARG 3 GO:2000106 regulation of leukocyte apoptotic process 3/445 81/18722 0.302790512689139 0.528237156610108 CD74/ANXA1/BIRC7 3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1/445 15/18722 0.303003287033232 0.528237156610108 ZNHIT6 1 GO:0002679 respiratory burst involved in defense response 1/445 15/18722 0.303003287033232 0.528237156610108 RPS19 1 GO:0002836 positive regulation of response to tumor cell 1/445 15/18722 0.303003287033232 0.528237156610108 HLA-DRB1 1 GO:0002839 positive regulation of immune response to tumor cell 1/445 15/18722 0.303003287033232 0.528237156610108 HLA-DRB1 1 GO:0003356 regulation of cilium beat frequency 1/445 15/18722 0.303003287033232 0.528237156610108 CCSAP 1 GO:0006089 lactate metabolic process 1/445 15/18722 0.303003287033232 0.528237156610108 LDHA 1 GO:0006878 cellular copper ion homeostasis 1/445 15/18722 0.303003287033232 0.528237156610108 MT2A 1 GO:0007000 nucleolus organization 1/445 15/18722 0.303003287033232 0.528237156610108 RPS19 1 GO:0009163 nucleoside biosynthetic process 1/445 15/18722 0.303003287033232 0.528237156610108 AMD1 1 GO:0010273 detoxification of copper ion 1/445 15/18722 0.303003287033232 0.528237156610108 MT2A 1 GO:0010452 histone H3-K36 methylation 1/445 15/18722 0.303003287033232 0.528237156610108 IWS1 1 GO:0010713 negative regulation of collagen metabolic process 1/445 15/18722 0.303003287033232 0.528237156610108 CST3 1 GO:0010763 positive regulation of fibroblast migration 1/445 15/18722 0.303003287033232 0.528237156610108 AKAP12 1 GO:0010820 positive regulation of T cell chemotaxis 1/445 15/18722 0.303003287033232 0.528237156610108 WNK1 1 GO:0010940 positive regulation of necrotic cell death 1/445 15/18722 0.303003287033232 0.528237156610108 BNIP3 1 GO:0014744 positive regulation of muscle adaptation 1/445 15/18722 0.303003287033232 0.528237156610108 AIF1 1 GO:0018410 C-terminal protein amino acid modification 1/445 15/18722 0.303003287033232 0.528237156610108 ATG12 1 GO:0030852 regulation of granulocyte differentiation 1/445 15/18722 0.303003287033232 0.528237156610108 HAX1 1 GO:0031269 pseudopodium assembly 1/445 15/18722 0.303003287033232 0.528237156610108 CDC42EP3 1 GO:0031958 corticosteroid receptor signaling pathway 1/445 15/18722 0.303003287033232 0.528237156610108 CALR 1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway 1/445 15/18722 0.303003287033232 0.528237156610108 LBH 1 GO:0033275 actin-myosin filament sliding 1/445 15/18722 0.303003287033232 0.528237156610108 TPM1 1 GO:0033599 regulation of mammary gland epithelial cell proliferation 1/445 15/18722 0.303003287033232 0.528237156610108 GATA3 1 GO:0034380 high-density lipoprotein particle assembly 1/445 15/18722 0.303003287033232 0.528237156610108 APOE 1 GO:0034384 high-density lipoprotein particle clearance 1/445 15/18722 0.303003287033232 0.528237156610108 APOE 1 GO:0034404 nucleobase-containing small molecule biosynthetic process 1/445 15/18722 0.303003287033232 0.528237156610108 AMD1 1 GO:0035493 SNARE complex assembly 1/445 15/18722 0.303003287033232 0.528237156610108 VAMP8 1 GO:0035627 ceramide transport 1/445 15/18722 0.303003287033232 0.528237156610108 PSAP 1 GO:0036124 histone H3-K9 trimethylation 1/445 15/18722 0.303003287033232 0.528237156610108 SMARCB1 1 GO:0042249 establishment of planar polarity of embryonic epithelium 1/445 15/18722 0.303003287033232 0.528237156610108 SFRP1 1 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator 1/445 15/18722 0.303003287033232 0.528237156610108 CD74 1 GO:0044406 adhesion of symbiont to host 1/445 15/18722 0.303003287033232 0.528237156610108 HSP90AB1 1 GO:0044793 negative regulation by host of viral process 1/445 15/18722 0.303003287033232 0.528237156610108 EIF2AK4 1 GO:0045346 regulation of MHC class II biosynthetic process 1/445 15/18722 0.303003287033232 0.528237156610108 TAF7 1 GO:0050746 regulation of lipoprotein metabolic process 1/445 15/18722 0.303003287033232 0.528237156610108 DBI 1 GO:0051127 positive regulation of actin nucleation 1/445 15/18722 0.303003287033232 0.528237156610108 GSN 1 GO:0051284 positive regulation of sequestering of calcium ion 1/445 15/18722 0.303003287033232 0.528237156610108 SRI 1 GO:0051608 histamine transport 1/445 15/18722 0.303003287033232 0.528237156610108 VAMP8 1 GO:0051938 L-glutamate import 1/445 15/18722 0.303003287033232 0.528237156610108 SLC1A6 1 GO:0055012 ventricular cardiac muscle cell differentiation 1/445 15/18722 0.303003287033232 0.528237156610108 FHL2 1 GO:0060026 convergent extension 1/445 15/18722 0.303003287033232 0.528237156610108 SFRP1 1 GO:0060049 regulation of protein glycosylation 1/445 15/18722 0.303003287033232 0.528237156610108 GOLGA2 1 GO:0060413 atrial septum morphogenesis 1/445 15/18722 0.303003287033232 0.528237156610108 SOX4 1 GO:0060766 negative regulation of androgen receptor signaling pathway 1/445 15/18722 0.303003287033232 0.528237156610108 SFRP1 1 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade 1/445 15/18722 0.303003287033232 0.528237156610108 FHL2 1 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade 1/445 15/18722 0.303003287033232 0.528237156610108 CAMTA1 1 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus 1/445 15/18722 0.303003287033232 0.528237156610108 RPS15 1 GO:0071599 otic vesicle development 1/445 15/18722 0.303003287033232 0.528237156610108 GATA3 1 GO:0072075 metanephric mesenchyme development 1/445 15/18722 0.303003287033232 0.528237156610108 BASP1 1 GO:0090594 inflammatory response to wounding 1/445 15/18722 0.303003287033232 0.528237156610108 HMOX1 1 GO:0097468 programmed cell death in response to reactive oxygen species 1/445 15/18722 0.303003287033232 0.528237156610108 PAWR 1 GO:0098712 L-glutamate import across plasma membrane 1/445 15/18722 0.303003287033232 0.528237156610108 SLC1A6 1 GO:0099170 postsynaptic modulation of chemical synaptic transmission 1/445 15/18722 0.303003287033232 0.528237156610108 EIF4A3 1 GO:0106057 negative regulation of calcineurin-mediated signaling 1/445 15/18722 0.303003287033232 0.528237156610108 FHL2 1 GO:0106058 positive regulation of calcineurin-mediated signaling 1/445 15/18722 0.303003287033232 0.528237156610108 CAMTA1 1 GO:0140374 antiviral innate immune response 1/445 15/18722 0.303003287033232 0.528237156610108 MX1 1 GO:0150011 regulation of neuron projection arborization 1/445 15/18722 0.303003287033232 0.528237156610108 MACF1 1 GO:1900102 negative regulation of endoplasmic reticulum unfolded protein response 1/445 15/18722 0.303003287033232 0.528237156610108 PPP1R15A 1 GO:1901841 regulation of high voltage-gated calcium channel activity 1/445 15/18722 0.303003287033232 0.528237156610108 SRI 1 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel 1/445 15/18722 0.303003287033232 0.528237156610108 SESTD1 1 GO:1903729 regulation of plasma membrane organization 1/445 15/18722 0.303003287033232 0.528237156610108 GSN 1 GO:1904874 positive regulation of telomerase RNA localization to Cajal body 1/445 15/18722 0.303003287033232 0.528237156610108 CCT6A 1 GO:1904889 regulation of excitatory synapse assembly 1/445 15/18722 0.303003287033232 0.528237156610108 WNT7A 1 GO:1905146 lysosomal protein catabolic process 1/445 15/18722 0.303003287033232 0.528237156610108 LRP2 1 GO:1905288 vascular associated smooth muscle cell apoptotic process 1/445 15/18722 0.303003287033232 0.528237156610108 PPARG 1 GO:1905459 regulation of vascular associated smooth muscle cell apoptotic process 1/445 15/18722 0.303003287033232 0.528237156610108 PPARG 1 GO:1990169 stress response to copper ion 1/445 15/18722 0.303003287033232 0.528237156610108 MT2A 1 GO:1990822 basic amino acid transmembrane transport 1/445 15/18722 0.303003287033232 0.528237156610108 SLC7A1 1 GO:2000052 positive regulation of non-canonical Wnt signaling pathway 1/445 15/18722 0.303003287033232 0.528237156610108 SFRP1 1 GO:2001028 positive regulation of endothelial cell chemotaxis 1/445 15/18722 0.303003287033232 0.528237156610108 TMSB4X 1 GO:0072676 lymphocyte migration 4/445 117/18722 0.303055449326061 0.528237156610108 WNK1/AIF1/RHOA/GATA3 4 GO:0072594 establishment of protein localization to organelle 12/445 422/18722 0.304031497947098 0.529714938009052 NUTF2/NUP58/HAX1/RPL23/BNIP3L/MAN1A1/HSP90AB1/TXNIP/RAB8B/CCT6A/LAPTM5/DNAJA1 12 GO:0022412 cellular process involved in reproduction in multicellular organism 11/445 384/18722 0.306788639655362 0.534002823998993 SFRP1/CTNNB1/ING2/HSPA2/FNDC3A/TMF1/CDYL/FOXJ3/YTHDC1/GMCL1/UBE2J1 11 GO:0045055 regulated exocytosis 7/445 230/18722 0.307193468813452 0.534002823998993 WNT7A/RAP1B/HMOX1/CTBP2/CBL/VAMP8/RAB11FIP1 7 GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal 2/445 47/18722 0.307785215187994 0.534002823998993 TPM1/RHOA 2 GO:0006998 nuclear envelope organization 2/445 47/18722 0.307785215187994 0.534002823998993 ANKLE2/UBXN2A 2 GO:0014911 positive regulation of smooth muscle cell migration 2/445 47/18722 0.307785215187994 0.534002823998993 ADAMTS1/AIF1 2 GO:0032008 positive regulation of TOR signaling 2/445 47/18722 0.307785215187994 0.534002823998993 PIK3CA/GOLPH3 2 GO:0045601 regulation of endothelial cell differentiation 2/445 47/18722 0.307785215187994 0.534002823998993 CTNNB1/VEZF1 2 GO:0097028 dendritic cell differentiation 2/445 47/18722 0.307785215187994 0.534002823998993 HLA-B/CEBPB 2 GO:0120163 negative regulation of cold-induced thermogenesis 2/445 47/18722 0.307785215187994 0.534002823998993 PLCL2/ATF4 2 GO:1903170 negative regulation of calcium ion transmembrane transport 2/445 47/18722 0.307785215187994 0.534002823998993 SRI/SESTD1 2 GO:0009308 amine metabolic process 4/445 118/18722 0.308419000066376 0.534653331629962 GDPD3/SAT1/AMD1/GATA3 4 GO:1903313 positive regulation of mRNA metabolic process 4/445 118/18722 0.308419000066376 0.534653331629962 NCL/MEX3D/RBM3/HNRNPR 4 GO:0006606 protein import into nucleus 5/445 155/18722 0.308702277912884 0.53469564363024 NUTF2/NUP58/RPL23/HSP90AB1/TXNIP 5 GO:0007519 skeletal muscle tissue development 5/445 155/18722 0.308702277912884 0.53469564363024 FOS/IGSF8/CTNNB1/KLF5/RHOA 5 GO:0001935 endothelial cell proliferation 6/445 193/18722 0.310799269018002 0.538102171128821 APOE/HMOX1/PPARG/RGCC/SPARC/PDCD6 6 GO:0006909 phagocytosis 9/445 308/18722 0.311665253457465 0.539375434450267 TYROBP/ANXA1/VAV2/GSN/FCER1G/AIF1/PLSCR1/PIK3CA/CALR 9 GO:0045860 positive regulation of protein kinase activity 11/445 386/18722 0.312626074240502 0.539958644153206 STK3/ARHGEF5/FERMT2/PAK2/WNK1/SASH1/HSP90AB1/PIK3CA/RPLP1/RGCC/RHOA 11 GO:0043087 regulation of GTPase activity 10/445 348/18722 0.315538163858313 0.539958644153206 ARHGEF5/SFRP1/VAV2/ARHGAP29/FERMT2/CHN2/LIMS1/WNK1/NET1/RDX 10 GO:0002715 regulation of natural killer cell mediated immunity 2/445 48/18722 0.316578147051155 0.539958644153206 HLA-B/HLA-A 2 GO:0042149 cellular response to glucose starvation 2/445 48/18722 0.316578147051155 0.539958644153206 HNRNPA1/ATF4 2 GO:0061647 histone H3-K9 modification 2/445 48/18722 0.316578147051155 0.539958644153206 SMARCB1/GATA3 2 GO:0090311 regulation of protein deacetylation 2/445 48/18722 0.316578147051155 0.539958644153206 ING2/BEX4 2 GO:0097720 calcineurin-mediated signaling 2/445 48/18722 0.316578147051155 0.539958644153206 FHL2/CAMTA1 2 GO:0007030 Golgi organization 5/445 157/18722 0.318028932023524 0.539958644153206 UBXN2A/ARHGAP21/GOLGA2/YWHAZ/GOLPH3 5 GO:0007034 vacuolar transport 5/445 157/18722 0.318028932023524 0.539958644153206 AP3S1/RHOB/CHMP5/LAPTM5/PSAP 5 GO:1902600 proton transmembrane transport 5/445 157/18722 0.318028932023524 0.539958644153206 TMSB4X/UQCR10/COX6A1/NDUFA4/COX4I1 5 GO:0006304 DNA modification 4/445 120/18722 0.31917331538696 0.539958644153206 FOS/MBD2/PIK3CA/GATA3 4 GO:0048593 camera-type eye morphogenesis 4/445 120/18722 0.31917331538696 0.539958644153206 CTNNB1/THRB/HMGN1/ATF4 4 GO:0071774 response to fibroblast growth factor 4/445 120/18722 0.31917331538696 0.539958644153206 SFRP1/CTNNB1/IER2/GATA3 4 GO:0005980 glycogen catabolic process 1/445 16/18722 0.319583366002079 0.539958644153206 RB1CC1 1 GO:0006206 pyrimidine nucleobase metabolic process 1/445 16/18722 0.319583366002079 0.539958644153206 CDA 1 GO:0006828 manganese ion transport 1/445 16/18722 0.319583366002079 0.539958644153206 TMEM165 1 GO:0006857 oligopeptide transport 1/445 16/18722 0.319583366002079 0.539958644153206 CA2 1 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 1/445 16/18722 0.319583366002079 0.539958644153206 SP100 1 GO:0009299 mRNA transcription 1/445 16/18722 0.319583366002079 0.539958644153206 ATF4 1 GO:0010225 response to UV-C 1/445 16/18722 0.319583366002079 0.539958644153206 HMGN1 1 GO:0010649 regulation of cell communication by electrical coupling 1/445 16/18722 0.319583366002079 0.539958644153206 SRI 1 GO:0010819 regulation of T cell chemotaxis 1/445 16/18722 0.319583366002079 0.539958644153206 WNK1 1 GO:0016584 nucleosome positioning 1/445 16/18722 0.319583366002079 0.539958644153206 RSF1 1 GO:0021535 cell migration in hindbrain 1/445 16/18722 0.319583366002079 0.539958644153206 SEMA4C 1 GO:0021783 preganglionic parasympathetic fiber development 1/445 16/18722 0.319583366002079 0.539958644153206 NAV2 1 GO:0030033 microvillus assembly 1/445 16/18722 0.319583366002079 0.539958644153206 KLF5 1 GO:0030540 female genitalia development 1/445 16/18722 0.319583366002079 0.539958644153206 LRP2 1 GO:0030575 nuclear body organization 1/445 16/18722 0.319583366002079 0.539958644153206 SERBP1 1 GO:0031268 pseudopodium organization 1/445 16/18722 0.319583366002079 0.539958644153206 CDC42EP3 1 GO:0034374 low-density lipoprotein particle remodeling 1/445 16/18722 0.319583366002079 0.539958644153206 APOE 1 GO:0034393 positive regulation of smooth muscle cell apoptotic process 1/445 16/18722 0.319583366002079 0.539958644153206 PPARG 1 GO:0035067 negative regulation of histone acetylation 1/445 16/18722 0.319583366002079 0.539958644153206 TAF7 1 GO:0035751 regulation of lysosomal lumen pH 1/445 16/18722 0.319583366002079 0.539958644153206 TMEM165 1 GO:0035970 peptidyl-threonine dephosphorylation 1/445 16/18722 0.319583366002079 0.539958644153206 PPM1G 1 GO:0045342 MHC class II biosynthetic process 1/445 16/18722 0.319583366002079 0.539958644153206 TAF7 1 GO:0045721 negative regulation of gluconeogenesis 1/445 16/18722 0.319583366002079 0.539958644153206 FAM3C 1 GO:0046135 pyrimidine nucleoside catabolic process 1/445 16/18722 0.319583366002079 0.539958644153206 CDA 1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis 1/445 16/18722 0.319583366002079 0.539958644153206 APOE 1 GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process 1/445 16/18722 0.319583366002079 0.539958644153206 AKAP12 1 GO:0055089 fatty acid homeostasis 1/445 16/18722 0.319583366002079 0.539958644153206 APOE 1 GO:0060572 morphogenesis of an epithelial bud 1/445 16/18722 0.319583366002079 0.539958644153206 CTNNB1 1 GO:0061548 ganglion development 1/445 16/18722 0.319583366002079 0.539958644153206 CTNNB1 1 GO:0070200 establishment of protein localization to telomere 1/445 16/18722 0.319583366002079 0.539958644153206 CCT6A 1 GO:0070365 hepatocyte differentiation 1/445 16/18722 0.319583366002079 0.539958644153206 ANXA1 1 GO:0070431 nucleotide-binding oligomerization domain containing 2 signaling pathway 1/445 16/18722 0.319583366002079 0.539958644153206 HSPA1B 1 GO:0070571 negative regulation of neuron projection regeneration 1/445 16/18722 0.319583366002079 0.539958644153206 SPP1 1 GO:0072283 metanephric renal vesicle morphogenesis 1/445 16/18722 0.319583366002079 0.539958644153206 CTNNB1 1 GO:0090336 positive regulation of brown fat cell differentiation 1/445 16/18722 0.319583366002079 0.539958644153206 PIM1 1 GO:0099010 modification of postsynaptic structure 1/445 16/18722 0.319583366002079 0.539958644153206 RHOA 1 GO:1901163 regulation of trophoblast cell migration 1/445 16/18722 0.319583366002079 0.539958644153206 CALR 1 GO:1901201 regulation of extracellular matrix assembly 1/445 16/18722 0.319583366002079 0.539958644153206 RGCC 1 GO:1902931 negative regulation of alcohol biosynthetic process 1/445 16/18722 0.319583366002079 0.539958644153206 APOE 1 GO:1905874 regulation of postsynaptic density organization 1/445 16/18722 0.319583366002079 0.539958644153206 ZMYND8 1 GO:1905906 regulation of amyloid fibril formation 1/445 16/18722 0.319583366002079 0.539958644153206 APOE 1 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway 1/445 16/18722 0.319583366002079 0.539958644153206 SFRP1 1 GO:2000651 positive regulation of sodium ion transmembrane transporter activity 1/445 16/18722 0.319583366002079 0.539958644153206 WNK1 1 GO:2001224 positive regulation of neuron migration 1/445 16/18722 0.319583366002079 0.539958644153206 SHTN1 1 GO:2001267 regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 1/445 16/18722 0.319583366002079 0.539958644153206 GSN 1 GO:0010660 regulation of muscle cell apoptotic process 3/445 84/18722 0.322356838650521 0.544199468927381 BNIP3/HMOX1/PPARG 3 GO:0045445 myoblast differentiation 3/445 84/18722 0.322356838650521 0.544199468927381 IGFBP3/IFRD1/TCF7L2 3 GO:0090276 regulation of peptide hormone secretion 6/445 196/18722 0.323326569831667 0.54523356478562 SFRP1/HLA-DRB1/SRI/SOX4/RAB8B/TCF7L2 6 GO:0042177 negative regulation of protein catabolic process 4/445 121/18722 0.324561754410502 0.54523356478562 RYBP/RPL23/HSP90AB1/CST3 4 GO:0043500 muscle adaptation 4/445 121/18722 0.324561754410502 0.54523356478562 KLF4/HMOX1/GSN/AIF1 4 GO:0048706 embryonic skeletal system development 4/445 121/18722 0.324561754410502 0.54523356478562 MTHFD1L/OSR2/CTNNB1/EIF4A3 4 GO:0006953 acute-phase response 2/445 49/18722 0.325345131250679 0.54523356478562 CEBPB/PLSCR1 2 GO:0009066 aspartate family amino acid metabolic process 2/445 49/18722 0.325345131250679 0.54523356478562 PLOD2/ATF4 2 GO:0009395 phospholipid catabolic process 2/445 49/18722 0.325345131250679 0.54523356478562 APOC1/GDPD3 2 GO:0010823 negative regulation of mitochondrion organization 2/445 49/18722 0.325345131250679 0.54523356478562 BNIP3/PPARG 2 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation 2/445 49/18722 0.325345131250679 0.54523356478562 INHA/PPARG 2 GO:0018198 peptidyl-cysteine modification 2/445 49/18722 0.325345131250679 0.54523356478562 S100A9/S100A8 2 GO:0021515 cell differentiation in spinal cord 2/445 49/18722 0.325345131250679 0.54523356478562 SOX4/LMO4 2 GO:0021695 cerebellar cortex development 2/445 49/18722 0.325345131250679 0.54523356478562 WNT7A/UQCRQ 2 GO:0030225 macrophage differentiation 2/445 49/18722 0.325345131250679 0.54523356478562 HLA-DRB1/INHA 2 GO:0038084 vascular endothelial growth factor signaling pathway 2/445 49/18722 0.325345131250679 0.54523356478562 CD63/PIK3CA 2 GO:0045778 positive regulation of ossification 2/445 49/18722 0.325345131250679 0.54523356478562 OSR2/FBN2 2 GO:0050832 defense response to fungus 2/445 49/18722 0.325345131250679 0.54523356478562 S100A9/S100A8 2 GO:1901799 negative regulation of proteasomal protein catabolic process 2/445 49/18722 0.325345131250679 0.54523356478562 RYBP/HSP90AB1 2 GO:1904894 positive regulation of receptor signaling pathway via STAT 2/445 49/18722 0.325345131250679 0.54523356478562 CENPJ/CSH1 2 GO:0045930 negative regulation of mitotic cell cycle 7/445 235/18722 0.326226709380301 0.546489268633424 KLF4/CTNNB1/SOX4/PLK2/BRD7/RGCC/WEE1 7 GO:0030433 ubiquitin-dependent ERAD pathway 3/445 85/18722 0.328882793824918 0.549823885589129 MAN1A1/CALR/UBE2J1 3 GO:0045069 regulation of viral genome replication 3/445 85/18722 0.328882793824918 0.549823885589129 EIF2AK2/MX1/PLSCR1 3 GO:0060021 roof of mouth development 3/445 85/18722 0.328882793824918 0.549823885589129 OSR2/WNT7A/TMEM107 3 GO:0097006 regulation of plasma lipoprotein particle levels 3/445 85/18722 0.328882793824918 0.549823885589129 APOE/APOC1/HMOX1 3 GO:0097194 execution phase of apoptosis 3/445 85/18722 0.328882793824918 0.549823885589129 DFFB/PAK2/PLSCR1 3 GO:1990266 neutrophil migration 4/445 122/18722 0.329956188449847 0.549986311799175 CD74/S100A9/S100A8/FCER1G 4 GO:0048738 cardiac muscle tissue development 7/445 236/18722 0.330056685013906 0.549986311799175 TPM1/PIM1/PKP2/LRP2/CALR/FHL2/DSP 7 GO:0006066 alcohol metabolic process 10/445 353/18722 0.33109076177906 0.549986311799175 APOE/IMPA2/LIMA1/ISYNA1/PTS/RXRA/GDPD3/FDX1/OSBPL1A/PLPP3 10 GO:0050864 regulation of B cell activation 6/445 198/18722 0.331717967734492 0.549986311799175 CD74/SFRP1/TYROBP/PAWR/INHA/LAPTM5 6 GO:0031334 positive regulation of protein-containing complex assembly 7/445 237/18722 0.333893459836575 0.549986311799175 CDC42EP3/RAP1B/GSN/FERMT2/HSPA1B/GRB2/RHOA 7 GO:1901617 organic hydroxy compound biosynthetic process 7/445 237/18722 0.333893459836575 0.549986311799175 APOE/IMPA2/ISYNA1/PTS/HSD17B1/OSBPL1A/GATA3 7 GO:0038093 Fc receptor signaling pathway 2/445 50/18722 0.334082439101485 0.549986311799175 VAV2/FCER1G 2 GO:0060688 regulation of morphogenesis of a branching structure 2/445 50/18722 0.334082439101485 0.549986311799175 SFRP1/CTNNB1 2 GO:0071709 membrane assembly 2/445 50/18722 0.334082439101485 0.549986311799175 ANKLE2/UBXN2A 2 GO:0071825 protein-lipid complex subunit organization 2/445 50/18722 0.334082439101485 0.549986311799175 APOE/APOC1 2 GO:1903829 positive regulation of cellular protein localization 8/445 276/18722 0.334759655860915 0.549986311799175 GNL3/NUTF2/TYROBP/FERMT2/HSP90AB1/WWTR1/RDX/CCT6A 8 GO:0006690 icosanoid metabolic process 4/445 123/18722 0.335355491956622 0.549986311799175 CD74/ANXA1/GSTP1/HPGD 4 GO:0022406 membrane docking 3/445 86/18722 0.335407500231494 0.549986311799175 CTBP2/RAB8B/VAMP8 3 GO:0048864 stem cell development 3/445 86/18722 0.335407500231494 0.549986311799175 WNT7A/SEMA4C/PDCD6 3 GO:0001675 acrosome assembly 1/445 17/18722 0.335769905194268 0.549986311799175 TMF1 1 GO:0001710 mesodermal cell fate commitment 1/445 17/18722 0.335769905194268 0.549986311799175 KLF4 1 GO:0001780 neutrophil homeostasis 1/445 17/18722 0.335769905194268 0.549986311799175 ANXA1 1 GO:0006474 N-terminal protein amino acid acetylation 1/445 17/18722 0.335769905194268 0.549986311799175 SOX4 1 GO:0007096 regulation of exit from mitosis 1/445 17/18722 0.335769905194268 0.549986311799175 RGCC 1 GO:0007351 tripartite regional subdivision 1/445 17/18722 0.335769905194268 0.549986311799175 BASP1 1 GO:0007379 segment specification 1/445 17/18722 0.335769905194268 0.549986311799175 IRX2 1 GO:0008595 anterior/posterior axis specification, embryo 1/445 17/18722 0.335769905194268 0.549986311799175 BASP1 1 GO:0009251 glucan catabolic process 1/445 17/18722 0.335769905194268 0.549986311799175 RB1CC1 1 GO:0010224 response to UV-B 1/445 17/18722 0.335769905194268 0.549986311799175 HMGN1 1 GO:0010715 regulation of extracellular matrix disassembly 1/445 17/18722 0.335769905194268 0.549986311799175 CST3 1 GO:0015867 ATP transport 1/445 17/18722 0.335769905194268 0.549986311799175 SLC25A24 1 GO:0016264 gap junction assembly 1/445 17/18722 0.335769905194268 0.549986311799175 CTNNA1 1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway 1/445 17/18722 0.335769905194268 0.549986311799175 CHMP5 1 GO:0034349 glial cell apoptotic process 1/445 17/18722 0.335769905194268 0.549986311799175 AKAP12 1 GO:0035518 histone H2A monoubiquitination 1/445 17/18722 0.335769905194268 0.549986311799175 RYBP 1 GO:0036035 osteoclast development 1/445 17/18722 0.335769905194268 0.549986311799175 TYROBP 1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process 1/445 17/18722 0.335769905194268 0.549986311799175 PIK3CA 1 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein 1/445 17/18722 0.335769905194268 0.549986311799175 PARP14 1 GO:0042772 DNA damage response, signal transduction resulting in transcription 1/445 17/18722 0.335769905194268 0.549986311799175 SP100 1 GO:0042953 lipoprotein transport 1/445 17/18722 0.335769905194268 0.549986311799175 PPARG 1 GO:0043968 histone H2A acetylation 1/445 17/18722 0.335769905194268 0.549986311799175 MORF4L2 1 GO:0045198 establishment of epithelial cell apical/basal polarity 1/445 17/18722 0.335769905194268 0.549986311799175 RHOA 1 GO:0046827 positive regulation of protein export from nucleus 1/445 17/18722 0.335769905194268 0.549986311799175 TCF7L2 1 GO:0046855 inositol phosphate dephosphorylation 1/445 17/18722 0.335769905194268 0.549986311799175 IMPA2 1 GO:0060263 regulation of respiratory burst 1/445 17/18722 0.335769905194268 0.549986311799175 RPS19 1 GO:0060977 coronary vasculature morphogenesis 1/445 17/18722 0.335769905194268 0.549986311799175 LRP2 1 GO:0061450 trophoblast cell migration 1/445 17/18722 0.335769905194268 0.549986311799175 CALR 1 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel 1/445 17/18722 0.335769905194268 0.549986311799175 SESTD1 1 GO:0061952 midbody abscission 1/445 17/18722 0.335769905194268 0.549986311799175 CHMP5 1 GO:0070206 protein trimerization 1/445 17/18722 0.335769905194268 0.549986311799175 CD74 1 GO:0072673 lamellipodium morphogenesis 1/445 17/18722 0.335769905194268 0.549986311799175 SNX2 1 GO:1900034 regulation of cellular response to heat 1/445 17/18722 0.335769905194268 0.549986311799175 IER5 1 GO:1900363 regulation of mRNA polyadenylation 1/445 17/18722 0.335769905194268 0.549986311799175 YTHDC1 1 GO:1901569 fatty acid derivative catabolic process 1/445 17/18722 0.335769905194268 0.549986311799175 HPGD 1 GO:1902358 sulfate transmembrane transport 1/445 17/18722 0.335769905194268 0.549986311799175 SLC13A4 1 GO:1902894 negative regulation of pri-miRNA transcription by RNA polymerase II 1/445 17/18722 0.335769905194268 0.549986311799175 PPARG 1 GO:0051650 establishment of vesicle localization 5/445 161/18722 0.33677831006888 0.55141942088567 AP3S1/CTNNB1/TANC2/ARFGAP3/PDCD6 5 GO:0043414 macromolecule methylation 9/445 316/18722 0.338104531264573 0.553371560480963 FOS/CTNNB1/IWS1/SMARCB1/MBD2/KMT2C/PIK3CA/RTF1/GATA3 9 GO:0010508 positive regulation of autophagy 4/445 124/18722 0.34075855485801 0.557494491136016 BNIP3/HMOX1/BNIP3L/PLK2 4 GO:0021953 central nervous system neuron differentiation 5/445 162/18722 0.341481247818626 0.558304033303754 WNT7A/SOX4/UQCRQ/HSP90AB1/LMO4 5 GO:0022898 regulation of transmembrane transporter activity 8/445 278/18722 0.341882294636663 0.558304033303754 TMSB4X/SRI/GOPC/PIM1/HSPA2/WNK1/CTSS/NDUFA4 8 GO:0001776 leukocyte homeostasis 3/445 87/18722 0.341929122309004 0.558304033303754 CD74/SKIL/ANXA1 3 GO:0044070 regulation of anion transport 3/445 87/18722 0.341929122309004 0.558304033303754 CA2/CEBPB/GOPC 3 GO:0051262 protein tetramerization 3/445 87/18722 0.341929122309004 0.558304033303754 STK3/HLA-DRB1/GOLGA2 3 GO:0006636 unsaturated fatty acid biosynthetic process 2/445 51/18722 0.342786533019932 0.558820508249937 CD74/ANXA1 2 GO:0021872 forebrain generation of neurons 2/445 51/18722 0.342786533019932 0.558820508249937 UQCRQ/RHOA 2 GO:0032964 collagen biosynthetic process 2/445 51/18722 0.342786533019932 0.558820508249937 VIM/RGCC 2 GO:0045668 negative regulation of osteoblast differentiation 2/445 51/18722 0.342786533019932 0.558820508249937 SFRP1/PPARG 2 GO:0065004 protein-DNA complex assembly 6/445 201/18722 0.34435391034252 0.560750911785367 TSPYL2/TAF7/BRD2/SMARCB1/SPTY2D1/RSF1 6 GO:0060294 cilium movement involved in cell motility 4/445 125/18722 0.346164282846385 0.560750911785367 ING2/CCSAP/TMF1/DNAJA1 4 GO:0009913 epidermal cell differentiation 6/445 202/18722 0.34857675355868 0.560750911785367 KLF4/CTNNB1/ANXA1/GRHL1/TXNIP/DSP 6 GO:0017157 regulation of exocytosis 6/445 202/18722 0.34857675355868 0.560750911785367 WNT7A/RAP1B/ANXA1/HMOX1/RAB8B/VAMP8 6 GO:0071824 protein-DNA complex subunit organization 7/445 241/18722 0.349300254076868 0.560750911785367 TSPYL2/TAF7/BRD2/SMARCB1/SPTY2D1/RPL23/RSF1 7 GO:0002218 activation of innate immune response 2/445 52/18722 0.351454059581143 0.560750911785367 TYROBP/PAK2 2 GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum 2/445 52/18722 0.351454059581143 0.560750911785367 PLPP3/GOLPH3 2 GO:0021545 cranial nerve development 2/445 52/18722 0.351454059581143 0.560750911785367 CTNNB1/NAV2 2 GO:0043277 apoptotic cell clearance 2/445 52/18722 0.351454059581143 0.560750911785367 TYROBP/ANXA1 2 GO:0048260 positive regulation of receptor-mediated endocytosis 2/445 52/18722 0.351454059581143 0.560750911785367 CBL/CD63 2 GO:1903426 regulation of reactive oxygen species biosynthetic process 2/445 52/18722 0.351454059581143 0.560750911785367 PAGE4/RHOA 2 GO:0002076 osteoblast development 1/445 18/18722 0.351572225011886 0.560750911785367 JUND 1 GO:0002643 regulation of tolerance induction 1/445 18/18722 0.351572225011886 0.560750911785367 HLA-B 1 GO:0003128 heart field specification 1/445 18/18722 0.351572225011886 0.560750911785367 LRP2 1 GO:0006337 nucleosome disassembly 1/445 18/18722 0.351572225011886 0.560750911785367 SMARCB1 1 GO:0006625 protein targeting to peroxisome 1/445 18/18722 0.351572225011886 0.560750911785367 RAB8B 1 GO:0008272 sulfate transport 1/445 18/18722 0.351572225011886 0.560750911785367 SLC13A4 1 GO:0010663 positive regulation of striated muscle cell apoptotic process 1/445 18/18722 0.351572225011886 0.560750911785367 BNIP3 1 GO:0010666 positive regulation of cardiac muscle cell apoptotic process 1/445 18/18722 0.351572225011886 0.560750911785367 BNIP3 1 GO:0010985 negative regulation of lipoprotein particle clearance 1/445 18/18722 0.351572225011886 0.560750911785367 APOC1 1 GO:0030299 intestinal cholesterol absorption 1/445 18/18722 0.351572225011886 0.560750911785367 LIMA1 1 GO:0032634 interleukin-5 production 1/445 18/18722 0.351572225011886 0.560750911785367 GATA3 1 GO:0032674 regulation of interleukin-5 production 1/445 18/18722 0.351572225011886 0.560750911785367 GATA3 1 GO:0035743 CD4-positive, alpha-beta T cell cytokine production 1/445 18/18722 0.351572225011886 0.560750911785367 GATA3 1 GO:0036507 protein demannosylation 1/445 18/18722 0.351572225011886 0.560750911785367 MAN1A1 1 GO:0036508 protein alpha-1,2-demannosylation 1/445 18/18722 0.351572225011886 0.560750911785367 MAN1A1 1 GO:0043217 myelin maintenance 1/445 18/18722 0.351572225011886 0.560750911785367 NDRG1 1 GO:0044247 cellular polysaccharide catabolic process 1/445 18/18722 0.351572225011886 0.560750911785367 RB1CC1 1 GO:0044872 lipoprotein localization 1/445 18/18722 0.351572225011886 0.560750911785367 PPARG 1 GO:0045623 negative regulation of T-helper cell differentiation 1/445 18/18722 0.351572225011886 0.560750911785367 ANXA1 1 GO:0046838 phosphorylated carbohydrate dephosphorylation 1/445 18/18722 0.351572225011886 0.560750911785367 IMPA2 1 GO:0046851 negative regulation of bone remodeling 1/445 18/18722 0.351572225011886 0.560750911785367 SFRP1 1 GO:0048486 parasympathetic nervous system development 1/445 18/18722 0.351572225011886 0.560750911785367 NAV2 1 GO:0048643 positive regulation of skeletal muscle tissue development 1/445 18/18722 0.351572225011886 0.560750911785367 CTNNB1 1 GO:0051782 negative regulation of cell division 1/445 18/18722 0.351572225011886 0.560750911785367 TXNIP 1 GO:0055070 copper ion homeostasis 1/445 18/18722 0.351572225011886 0.560750911785367 MT2A 1 GO:0060008 Sertoli cell differentiation 1/445 18/18722 0.351572225011886 0.560750911785367 FNDC3A 1 GO:0060391 positive regulation of SMAD protein signal transduction 1/445 18/18722 0.351572225011886 0.560750911785367 PPARG 1 GO:0060438 trachea development 1/445 18/18722 0.351572225011886 0.560750911785367 CTNNB1 1 GO:0060457 negative regulation of digestive system process 1/445 18/18722 0.351572225011886 0.560750911785367 WNK1 1 GO:0061484 hematopoietic stem cell homeostasis 1/445 18/18722 0.351572225011886 0.560750911785367 SOX4 1 GO:0061687 detoxification of inorganic compound 1/445 18/18722 0.351572225011886 0.560750911785367 MT2A 1 GO:0071071 regulation of phospholipid biosynthetic process 1/445 18/18722 0.351572225011886 0.560750911785367 LPCAT1 1 GO:0072189 ureter development 1/445 18/18722 0.351572225011886 0.560750911785367 GATA3 1 GO:0072234 metanephric nephron tubule development 1/445 18/18722 0.351572225011886 0.560750911785367 WWTR1 1 GO:0072662 protein localization to peroxisome 1/445 18/18722 0.351572225011886 0.560750911785367 RAB8B 1 GO:0072663 establishment of protein localization to peroxisome 1/445 18/18722 0.351572225011886 0.560750911785367 RAB8B 1 GO:0080182 histone H3-K4 trimethylation 1/445 18/18722 0.351572225011886 0.560750911785367 RTF1 1 GO:0097094 craniofacial suture morphogenesis 1/445 18/18722 0.351572225011886 0.560750911785367 TMEM107 1 GO:0099558 maintenance of synapse structure 1/445 18/18722 0.351572225011886 0.560750911785367 CTBP2 1 GO:1900225 regulation of NLRP3 inflammasome complex assembly 1/445 18/18722 0.351572225011886 0.560750911785367 EIF2AK2 1 GO:1902074 response to salt 1/445 18/18722 0.351572225011886 0.560750911785367 HNRNPA1 1 GO:1902683 regulation of receptor localization to synapse 1/445 18/18722 0.351572225011886 0.560750911785367 TYROBP 1 GO:1904872 regulation of telomerase RNA localization to Cajal body 1/445 18/18722 0.351572225011886 0.560750911785367 CCT6A 1 GO:1905820 positive regulation of chromosome separation 1/445 18/18722 0.351572225011886 0.560750911785367 PLSCR1 1 GO:2000641 regulation of early endosome to late endosome transport 1/445 18/18722 0.351572225011886 0.560750911785367 RDX 1 GO:0050804 modulation of chemical synaptic transmission 12/445 439/18722 0.351908841461842 0.561071178725924 APOE/WNT7A/RAP1B/TYROBP/ZMYND8/EIF2AK4/EIF4A3/PLK2/SRGN/AKAP12/PLCL2/ATF4 12 GO:0099177 regulation of trans-synaptic signaling 12/445 440/18722 0.354769314364987 0.565274950427302 APOE/WNT7A/RAP1B/TYROBP/ZMYND8/EIF2AK4/EIF4A3/PLK2/SRGN/AKAP12/PLCL2/ATF4 12 GO:0046330 positive regulation of JNK cascade 3/445 89/18722 0.354955996467785 0.565274950427302 STK3/WNT7A/RB1CC1 3 GO:0051781 positive regulation of cell division 3/445 89/18722 0.354955996467785 0.565274950427302 YBX1/LBH/RHOA 3 GO:0032635 interleukin-6 production 5/445 165/18722 0.35561561796288 0.565671204391473 CD74/HLA-B/CEBPB/TYROBP/AIF1 5 GO:0032675 regulation of interleukin-6 production 5/445 165/18722 0.35561561796288 0.565671204391473 CD74/HLA-B/CEBPB/TYROBP/AIF1 5 GO:0050796 regulation of insulin secretion 5/445 165/18722 0.35561561796288 0.565671204391473 SFRP1/HLA-DRB1/SRI/SOX4/TCF7L2 5 GO:0035270 endocrine system development 4/445 127/18722 0.356979437268261 0.567622038242951 CGA/ANXA1/SOX4/GATA3 4 GO:0002707 negative regulation of lymphocyte mediated immunity 2/445 53/18722 0.360081842797189 0.569952867356758 HLA-B/HLA-A 2 GO:0016925 protein sumoylation 2/445 53/18722 0.360081842797189 0.569952867356758 GNL3/CTNNB1 2 GO:0032784 regulation of DNA-templated transcription, elongation 2/445 53/18722 0.360081842797189 0.569952867356758 CTNNB1/HMGN1 2 GO:0043113 receptor clustering 2/445 53/18722 0.360081842797189 0.569952867356758 APOE/GSN 2 GO:0051438 regulation of ubiquitin-protein transferase activity 2/445 53/18722 0.360081842797189 0.569952867356758 RPS15/RPL23 2 GO:0071320 cellular response to cAMP 2/445 53/18722 0.360081842797189 0.569952867356758 RAP1B/FDX1 2 GO:0097479 synaptic vesicle localization 2/445 53/18722 0.360081842797189 0.569952867356758 AP3S1/CTNNB1 2 GO:1990090 cellular response to nerve growth factor stimulus 2/445 53/18722 0.360081842797189 0.569952867356758 EIF4A3/CBL 2 GO:0060348 bone development 6/445 205/18722 0.361270404931877 0.569952867356758 OSR2/TYROBP/HSD17B1/SBDS/TMEM107/RHOA 6 GO:0002028 regulation of sodium ion transport 3/445 90/18722 0.361457802342251 0.569952867356758 NKAIN4/PKP2/WNK1 3 GO:0032392 DNA geometric change 3/445 90/18722 0.361457802342251 0.569952867356758 HMGB3/ANXA1/NAV2 3 GO:0045638 negative regulation of myeloid cell differentiation 3/445 90/18722 0.361457802342251 0.569952867356758 SFRP1/CTNNB1/INHA 3 GO:0061097 regulation of protein tyrosine kinase activity 3/445 90/18722 0.361457802342251 0.569952867356758 SH3BP5/PAK2/CBL 3 GO:0032612 interleukin-1 production 4/445 128/18722 0.36238675622333 0.569952867356758 NLRP2/TYROBP/ANXA1/GSTP1 4 GO:0032652 regulation of interleukin-1 production 4/445 128/18722 0.36238675622333 0.569952867356758 NLRP2/TYROBP/ANXA1/GSTP1 4 GO:0035303 regulation of dephosphorylation 4/445 128/18722 0.36238675622333 0.569952867356758 ANKLE2/PPP1R15A/HSP90AB1/CAMTA1 4 GO:0098656 anion transmembrane transport 7/445 245/18722 0.36478285000134 0.569952867356758 SLC16A3/GOPC/SLC7A1/LRP2/SLC1A6/SLC7A5/SLC13A4 7 GO:0034728 nucleosome organization 5/445 167/18722 0.365052587706199 0.569952867356758 TSPYL2/BRD2/SMARCB1/SPTY2D1/RSF1 5 GO:0000729 DNA double-strand break processing 1/445 19/18722 0.366999425603722 0.569952867356758 UBE2V2 1 GO:0002281 macrophage activation involved in immune response 1/445 19/18722 0.366999425603722 0.569952867356758 TYROBP 1 GO:0002888 positive regulation of myeloid leukocyte mediated immunity 1/445 19/18722 0.366999425603722 0.569952867356758 TYROBP 1 GO:0002902 regulation of B cell apoptotic process 1/445 19/18722 0.366999425603722 0.569952867356758 CD74 1 GO:0006309 apoptotic DNA fragmentation 1/445 19/18722 0.366999425603722 0.569952867356758 DFFB 1 GO:0006491 N-glycan processing 1/445 19/18722 0.366999425603722 0.569952867356758 MAN1A1 1 GO:0006670 sphingosine metabolic process 1/445 19/18722 0.366999425603722 0.569952867356758 PLPP3 1 GO:0007039 protein catabolic process in the vacuole 1/445 19/18722 0.366999425603722 0.569952867356758 LRP2 1 GO:0007213 G protein-coupled acetylcholine receptor signaling pathway 1/445 19/18722 0.366999425603722 0.569952867356758 GNB1 1 GO:0010544 negative regulation of platelet activation 1/445 19/18722 0.366999425603722 0.569952867356758 APOE 1 GO:0010738 regulation of protein kinase A signaling 1/445 19/18722 0.366999425603722 0.569952867356758 AKAP12 1 GO:0010885 regulation of cholesterol storage 1/445 19/18722 0.366999425603722 0.569952867356758 PPARG 1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling 1/445 19/18722 0.366999425603722 0.569952867356758 KLF4 1 GO:0015802 basic amino acid transport 1/445 19/18722 0.366999425603722 0.569952867356758 SLC7A1 1 GO:0031065 positive regulation of histone deacetylation 1/445 19/18722 0.366999425603722 0.569952867356758 ING2 1 GO:0032616 interleukin-13 production 1/445 19/18722 0.366999425603722 0.569952867356758 GATA3 1 GO:0032656 regulation of interleukin-13 production 1/445 19/18722 0.366999425603722 0.569952867356758 GATA3 1 GO:0033194 response to hydroperoxide 1/445 19/18722 0.366999425603722 0.569952867356758 AIF1 1 GO:0035461 vitamin transmembrane transport 1/445 19/18722 0.366999425603722 0.569952867356758 LRP2 1 GO:0042474 middle ear morphogenesis 1/445 19/18722 0.366999425603722 0.569952867356758 OSR2 1 GO:0044003 modulation by symbiont of host process 1/445 19/18722 0.366999425603722 0.569952867356758 RXRA 1 GO:0044546 NLRP3 inflammasome complex assembly 1/445 19/18722 0.366999425603722 0.569952867356758 EIF2AK2 1 GO:0044827 modulation by host of viral genome replication 1/445 19/18722 0.366999425603722 0.569952867356758 EIF2AK4 1 GO:0046653 tetrahydrofolate metabolic process 1/445 19/18722 0.366999425603722 0.569952867356758 MTHFD1L 1 GO:0046782 regulation of viral transcription 1/445 19/18722 0.366999425603722 0.569952867356758 RSF1 1 GO:0048490 anterograde synaptic vesicle transport 1/445 19/18722 0.366999425603722 0.569952867356758 AP3S1 1 GO:0070734 histone H3-K27 methylation 1/445 19/18722 0.366999425603722 0.569952867356758 GATA3 1 GO:0071545 inositol phosphate catabolic process 1/445 19/18722 0.366999425603722 0.569952867356758 IMPA2 1 GO:0072074 kidney mesenchyme development 1/445 19/18722 0.366999425603722 0.569952867356758 BASP1 1 GO:0072077 renal vesicle morphogenesis 1/445 19/18722 0.366999425603722 0.569952867356758 CTNNB1 1 GO:0090670 RNA localization to Cajal body 1/445 19/18722 0.366999425603722 0.569952867356758 CCT6A 1 GO:0090671 telomerase RNA localization to Cajal body 1/445 19/18722 0.366999425603722 0.569952867356758 CCT6A 1 GO:0090672 telomerase RNA localization 1/445 19/18722 0.366999425603722 0.569952867356758 CCT6A 1 GO:0090685 RNA localization to nucleus 1/445 19/18722 0.366999425603722 0.569952867356758 CCT6A 1 GO:0097501 stress response to metal ion 1/445 19/18722 0.366999425603722 0.569952867356758 MT2A 1 GO:0098780 response to mitochondrial depolarisation 1/445 19/18722 0.366999425603722 0.569952867356758 CDC37 1 GO:0099514 synaptic vesicle cytoskeletal transport 1/445 19/18722 0.366999425603722 0.569952867356758 AP3S1 1 GO:0099517 synaptic vesicle transport along microtubule 1/445 19/18722 0.366999425603722 0.569952867356758 AP3S1 1 GO:0140131 positive regulation of lymphocyte chemotaxis 1/445 19/18722 0.366999425603722 0.569952867356758 WNK1 1 GO:1900221 regulation of amyloid-beta clearance 1/445 19/18722 0.366999425603722 0.569952867356758 APOE 1 GO:1901659 glycosyl compound biosynthetic process 1/445 19/18722 0.366999425603722 0.569952867356758 AMD1 1 GO:1901881 positive regulation of protein depolymerization 1/445 19/18722 0.366999425603722 0.569952867356758 DSTN 1 GO:2000251 positive regulation of actin cytoskeleton reorganization 1/445 19/18722 0.366999425603722 0.569952867356758 HAX1 1 GO:2000319 regulation of T-helper 17 cell differentiation 1/445 19/18722 0.366999425603722 0.569952867356758 NFKBIZ 1 GO:0006334 nucleosome assembly 4/445 129/18722 0.367792525743344 0.570184526920722 TSPYL2/BRD2/SPTY2D1/RSF1 4 GO:0002065 columnar/cuboidal epithelial cell differentiation 3/445 91/18722 0.36794963115893 0.570184526920722 CEBPB/SOX4/KLF5 3 GO:0006354 DNA-templated transcription, elongation 3/445 91/18722 0.36794963115893 0.570184526920722 CTNNB1/HMGN1/RTF1 3 GO:0014033 neural crest cell differentiation 3/445 91/18722 0.36794963115893 0.570184526920722 SFRP1/SEMA4C/PDCD6 3 GO:0006968 cellular defense response 2/445 54/18722 0.368666877609598 0.570184526920722 TYROBP/VEZF1 2 GO:0010659 cardiac muscle cell apoptotic process 2/445 54/18722 0.368666877609598 0.570184526920722 BNIP3/GNB1 2 GO:0032330 regulation of chondrocyte differentiation 2/445 54/18722 0.368666877609598 0.570184526920722 CTNNB1/EFEMP1 2 GO:0070228 regulation of lymphocyte apoptotic process 2/445 54/18722 0.368666877609598 0.570184526920722 CD74/BIRC7 2 GO:0086002 cardiac muscle cell action potential involved in contraction 2/445 54/18722 0.368666877609598 0.570184526920722 PKP2/DSP 2 GO:2000179 positive regulation of neural precursor cell proliferation 2/445 54/18722 0.368666877609598 0.570184526920722 CTNNB1/LRP2 2 GO:2000300 regulation of synaptic vesicle exocytosis 2/445 54/18722 0.368666877609598 0.570184526920722 WNT7A/RAP1B 2 GO:0002706 regulation of lymphocyte mediated immunity 5/445 168/18722 0.369773156333952 0.571681477850133 HLA-B/HLA-DRA/HLA-DRB1/HLA-A/GATA3 5 GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 4/445 130/18722 0.373195733963122 0.576757043397552 GOPC/GOLGA2/IER3IP1/PDCD6 4 GO:0032465 regulation of cytokinesis 3/445 92/18722 0.374429871332241 0.578331018610843 PRPF40A/PLK2/RHOA 3 GO:0021543 pallium development 5/445 169/18722 0.37449418416461 0.578331018610843 CTNNB1/BNIP3/UBA6/UQCRQ/RHOA 5 GO:0000768 syncytium formation by plasma membrane fusion 2/445 55/18722 0.377206323589837 0.580040970082413 TYROBP/MYOF 2 GO:0003179 heart valve morphogenesis 2/445 55/18722 0.377206323589837 0.580040970082413 SOX4/GATA3 2 GO:0006414 translational elongation 2/445 55/18722 0.377206323589837 0.580040970082413 EIF4A3/RPLP1 2 GO:0008333 endosome to lysosome transport 2/445 55/18722 0.377206323589837 0.580040970082413 RHOB/CHMP5 2 GO:0044091 membrane biogenesis 2/445 55/18722 0.377206323589837 0.580040970082413 ANKLE2/UBXN2A 2 GO:0046164 alcohol catabolic process 2/445 55/18722 0.377206323589837 0.580040970082413 APOE/IMPA2 2 GO:0048016 inositol phosphate-mediated signaling 2/445 55/18722 0.377206323589837 0.580040970082413 FHL2/CAMTA1 2 GO:0051898 negative regulation of protein kinase B signaling 2/445 55/18722 0.377206323589837 0.580040970082413 KLF4/PDCD6 2 GO:0098900 regulation of action potential 2/445 55/18722 0.377206323589837 0.580040970082413 PKP2/DSP 2 GO:0140253 cell-cell fusion 2/445 55/18722 0.377206323589837 0.580040970082413 TYROBP/MYOF 2 GO:0007259 receptor signaling pathway via JAK-STAT 5/445 170/18722 0.379214983750839 0.580040970082413 IFNAR1/CENPJ/PARP14/JAK1/CSH1 5 GO:1901988 negative regulation of cell cycle phase transition 7/445 249/18722 0.380315378870188 0.580040970082413 KLF4/SOX4/EIF2AK4/PLK2/BRD7/RGCC/WEE1 7 GO:0032755 positive regulation of interleukin-6 production 3/445 93/18722 0.380896955462403 0.580040970082413 CD74/TYROBP/AIF1 3 GO:0033108 mitochondrial respiratory chain complex assembly 3/445 93/18722 0.380896955462403 0.580040970082413 NDUFB2/NDUFA3/NDUFB1 3 GO:0000272 polysaccharide catabolic process 1/445 20/18722 0.382060392058641 0.580040970082413 RB1CC1 1 GO:0002577 regulation of antigen processing and presentation 1/445 20/18722 0.382060392058641 0.580040970082413 CD74 1 GO:0002834 regulation of response to tumor cell 1/445 20/18722 0.382060392058641 0.580040970082413 HLA-DRB1 1 GO:0002837 regulation of immune response to tumor cell 1/445 20/18722 0.382060392058641 0.580040970082413 HLA-DRB1 1 GO:0006346 DNA methylation-dependent heterochromatin assembly 1/445 20/18722 0.382060392058641 0.580040970082413 MBD2 1 GO:0006448 regulation of translational elongation 1/445 20/18722 0.382060392058641 0.580040970082413 EIF4A3 1 GO:0009110 vitamin biosynthetic process 1/445 20/18722 0.382060392058641 0.580040970082413 RFK 1 GO:0009713 catechol-containing compound biosynthetic process 1/445 20/18722 0.382060392058641 0.580040970082413 GATA3 1 GO:0010523 negative regulation of calcium ion transport into cytosol 1/445 20/18722 0.382060392058641 0.580040970082413 SRI 1 GO:0010893 positive regulation of steroid biosynthetic process 1/445 20/18722 0.382060392058641 0.580040970082413 CGA 1 GO:0015919 peroxisomal membrane transport 1/445 20/18722 0.382060392058641 0.580040970082413 RAB8B 1 GO:0017121 plasma membrane phospholipid scrambling 1/445 20/18722 0.382060392058641 0.580040970082413 PLSCR1 1 GO:0021516 dorsal spinal cord development 1/445 20/18722 0.382060392058641 0.580040970082413 LMO4 1 GO:0031498 chromatin disassembly 1/445 20/18722 0.382060392058641 0.580040970082413 SMARCB1 1 GO:0032211 negative regulation of telomere maintenance via telomerase 1/445 20/18722 0.382060392058641 0.580040970082413 HNRNPA1 1 GO:0033005 positive regulation of mast cell activation 1/445 20/18722 0.382060392058641 0.580040970082413 VAMP8 1 GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate 1/445 20/18722 0.382060392058641 0.580040970082413 SMARCB1 1 GO:0042359 vitamin D metabolic process 1/445 20/18722 0.382060392058641 0.580040970082413 LRP2 1 GO:0042423 catecholamine biosynthetic process 1/445 20/18722 0.382060392058641 0.580040970082413 GATA3 1 GO:0043586 tongue development 1/445 20/18722 0.382060392058641 0.580040970082413 CTNNB1 1 GO:0043651 linoleic acid metabolic process 1/445 20/18722 0.382060392058641 0.580040970082413 GSTP1 1 GO:0043691 reverse cholesterol transport 1/445 20/18722 0.382060392058641 0.580040970082413 APOE 1 GO:0045063 T-helper 1 cell differentiation 1/445 20/18722 0.382060392058641 0.580040970082413 ANXA1 1 GO:0045844 positive regulation of striated muscle tissue development 1/445 20/18722 0.382060392058641 0.580040970082413 CTNNB1 1 GO:0046629 gamma-delta T cell activation 1/445 20/18722 0.382060392058641 0.580040970082413 SOX4 1 GO:0048636 positive regulation of muscle organ development 1/445 20/18722 0.382060392058641 0.580040970082413 CTNNB1 1 GO:0048670 regulation of collateral sprouting 1/445 20/18722 0.382060392058641 0.580040970082413 SPP1 1 GO:0061318 renal filtration cell differentiation 1/445 20/18722 0.382060392058641 0.580040970082413 BASP1 1 GO:0072087 renal vesicle development 1/445 20/18722 0.382060392058641 0.580040970082413 CTNNB1 1 GO:0072112 glomerular visceral epithelial cell differentiation 1/445 20/18722 0.382060392058641 0.580040970082413 BASP1 1 GO:0140632 inflammasome complex assembly 1/445 20/18722 0.382060392058641 0.580040970082413 EIF2AK2 1 GO:2000757 negative regulation of peptidyl-lysine acetylation 1/445 20/18722 0.382060392058641 0.580040970082413 TAF7 1 GO:0071103 DNA conformation change 8/445 290/18722 0.384983805030594 0.583205112633446 TSPYL2/DFFB/HMGB3/ANXA1/BRD2/SPTY2D1/NAV2/RSF1 8 GO:0010332 response to gamma radiation 2/445 56/18722 0.385697498841582 0.583205112633446 CBL/GATA3 2 GO:0010658 striated muscle cell apoptotic process 2/445 56/18722 0.385697498841582 0.583205112633446 BNIP3/GNB1 2 GO:0022029 telencephalon cell migration 2/445 56/18722 0.385697498841582 0.583205112633446 CTNNB1/RHOA 2 GO:0031122 cytoplasmic microtubule organization 2/445 56/18722 0.385697498841582 0.583205112633446 CENPJ/RHOA 2 GO:0032608 interferon-beta production 2/445 56/18722 0.385697498841582 0.583205112633446 RIOK3/IRF1 2 GO:0032648 regulation of interferon-beta production 2/445 56/18722 0.385697498841582 0.583205112633446 RIOK3/IRF1 2 GO:0046456 icosanoid biosynthetic process 2/445 56/18722 0.385697498841582 0.583205112633446 CD74/ANXA1 2 GO:0046622 positive regulation of organ growth 2/445 56/18722 0.385697498841582 0.583205112633446 PIM1/BASP1 2 GO:0048008 platelet-derived growth factor receptor signaling pathway 2/445 56/18722 0.385697498841582 0.583205112633446 CBL/TXNIP 2 GO:1990089 response to nerve growth factor 2/445 56/18722 0.385697498841582 0.583205112633446 EIF4A3/CBL 2 GO:0001738 morphogenesis of a polarized epithelium 3/445 94/18722 0.387349360046062 0.585274398811369 WNT7A/SFRP1/RHOA 3 GO:1903035 negative regulation of response to wounding 3/445 94/18722 0.387349360046062 0.585274398811369 APOE/SPP1/CLDN19 3 GO:0019216 regulation of lipid metabolic process 9/445 331/18722 0.388530177508657 0.586815177703891 APOE/APOC1/LPCAT1/CD74/CGA/ANXA1/VAV2/PPARG/PSAP 9 GO:0002221 pattern recognition receptor signaling pathway 5/445 172/18722 0.388653189590376 0.586815177703891 RIOK3/IRF1/HSPA1B/LSM14A/CTSS 5 GO:0010565 regulation of cellular ketone metabolic process 4/445 133/18722 0.389380129177888 0.587697958945508 APOC1/CD74/ANXA1/PPARG 4 GO:0000910 cytokinesis 5/445 173/18722 0.39336926256662 0.588732491249479 RHOB/PRPF40A/CHMP5/PLK2/RHOA 5 GO:0006694 steroid biosynthetic process 5/445 173/18722 0.39336926256662 0.588732491249479 APOE/CGA/HSD17B1/FDX1/OSBPL1A 5 GO:0006942 regulation of striated muscle contraction 3/445 95/18722 0.393785605154694 0.588732491249479 SRI/PKP2/DSP 3 GO:0048709 oligodendrocyte differentiation 3/445 95/18722 0.393785605154694 0.588732491249479 CTNNB1/BNIP3/GSTP1 3 GO:0050764 regulation of phagocytosis 3/445 95/18722 0.393785605154694 0.588732491249479 FCER1G/PLSCR1/CALR 3 GO:0006949 syncytium formation 2/445 57/18722 0.394137874098785 0.588732491249479 TYROBP/MYOF 2 GO:1902017 regulation of cilium assembly 2/445 57/18722 0.394137874098785 0.588732491249479 ODF2L/MAP4 2 GO:0001508 action potential 4/445 134/18722 0.394763317206891 0.588732491249479 SRI/PKP2/CLDN19/DSP 4 GO:0032147 activation of protein kinase activity 4/445 134/18722 0.394763317206891 0.588732491249479 WNK1/PIK3CA/RPLP1/RGCC 4 GO:0001502 cartilage condensation 1/445 21/18722 0.396763799476773 0.588732491249479 WNT7A 1 GO:0006925 inflammatory cell apoptotic process 1/445 21/18722 0.396763799476773 0.588732491249479 ANXA1 1 GO:0007063 regulation of sister chromatid cohesion 1/445 21/18722 0.396763799476773 0.588732491249479 CTNNB1 1 GO:0007289 spermatid nucleus differentiation 1/445 21/18722 0.396763799476773 0.588732491249479 TMF1 1 GO:0007350 blastoderm segmentation 1/445 21/18722 0.396763799476773 0.588732491249479 BASP1 1 GO:0007617 mating behavior 1/445 21/18722 0.396763799476773 0.588732491249479 THRB 1 GO:0009067 aspartate family amino acid biosynthetic process 1/445 21/18722 0.396763799476773 0.588732491249479 PLOD2 1 GO:0010766 negative regulation of sodium ion transport 1/445 21/18722 0.396763799476773 0.588732491249479 WNK1 1 GO:0010878 cholesterol storage 1/445 21/18722 0.396763799476773 0.588732491249479 PPARG 1 GO:0021533 cell differentiation in hindbrain 1/445 21/18722 0.396763799476773 0.588732491249479 WNT7A 1 GO:0030502 negative regulation of bone mineralization 1/445 21/18722 0.396763799476773 0.588732491249479 SRGN 1 GO:0033962 P-body assembly 1/445 21/18722 0.396763799476773 0.588732491249479 LSM14A 1 GO:0034312 diol biosynthetic process 1/445 21/18722 0.396763799476773 0.588732491249479 PTS 1 GO:0035020 regulation of Rac protein signal transduction 1/445 21/18722 0.396763799476773 0.588732491249479 GABARAP 1 GO:0042454 ribonucleoside catabolic process 1/445 21/18722 0.396763799476773 0.588732491249479 CDA 1 GO:0044241 lipid digestion 1/445 21/18722 0.396763799476773 0.588732491249479 LIMA1 1 GO:0044342 type B pancreatic cell proliferation 1/445 21/18722 0.396763799476773 0.588732491249479 SFRP1 1 GO:0045717 negative regulation of fatty acid biosynthetic process 1/445 21/18722 0.396763799476773 0.588732491249479 APOC1 1 GO:0046128 purine ribonucleoside metabolic process 1/445 21/18722 0.396763799476773 0.588732491249479 AMD1 1 GO:0046519 sphingoid metabolic process 1/445 21/18722 0.396763799476773 0.588732491249479 PLPP3 1 GO:0046597 negative regulation of viral entry into host cell 1/445 21/18722 0.396763799476773 0.588732491249479 GSN 1 GO:0046641 positive regulation of alpha-beta T cell proliferation 1/445 21/18722 0.396763799476773 0.588732491249479 HLA-A 1 GO:0046823 negative regulation of nucleocytoplasmic transport 1/445 21/18722 0.396763799476773 0.588732491249479 SP100 1 GO:0050849 negative regulation of calcium-mediated signaling 1/445 21/18722 0.396763799476773 0.588732491249479 FHL2 1 GO:0071605 monocyte chemotactic protein-1 production 1/445 21/18722 0.396763799476773 0.588732491249479 GSTP1 1 GO:0071637 regulation of monocyte chemotactic protein-1 production 1/445 21/18722 0.396763799476773 0.588732491249479 GSTP1 1 GO:0072111 cell proliferation involved in kidney development 1/445 21/18722 0.396763799476773 0.588732491249479 GATA3 1 GO:0072170 metanephric tubule development 1/445 21/18722 0.396763799476773 0.588732491249479 WWTR1 1 GO:0072243 metanephric nephron epithelium development 1/445 21/18722 0.396763799476773 0.588732491249479 WWTR1 1 GO:0072311 glomerular epithelial cell differentiation 1/445 21/18722 0.396763799476773 0.588732491249479 BASP1 1 GO:0090026 positive regulation of monocyte chemotaxis 1/445 21/18722 0.396763799476773 0.588732491249479 AIF1 1 GO:0090141 positive regulation of mitochondrial fission 1/445 21/18722 0.396763799476773 0.588732491249479 BNIP3 1 GO:0098856 intestinal lipid absorption 1/445 21/18722 0.396763799476773 0.588732491249479 LIMA1 1 GO:1900118 negative regulation of execution phase of apoptosis 1/445 21/18722 0.396763799476773 0.588732491249479 PAK2 1 GO:1901863 positive regulation of muscle tissue development 1/445 21/18722 0.396763799476773 0.588732491249479 CTNNB1 1 GO:1902307 positive regulation of sodium ion transmembrane transport 1/445 21/18722 0.396763799476773 0.588732491249479 WNK1 1 GO:1902473 regulation of protein localization to synapse 1/445 21/18722 0.396763799476773 0.588732491249479 WNT7A 1 GO:2000774 positive regulation of cellular senescence 1/445 21/18722 0.396763799476773 0.588732491249479 PAWR 1 GO:0048639 positive regulation of developmental growth 5/445 174/18722 0.398082441010707 0.590477042662561 PIM1/SHTN1/GOLGA4/BASP1/MACF1 5 GO:0042113 B cell activation 9/445 334/18722 0.398686722836114 0.590948996066016 CD74/SFRP1/TYROBP/PAWR/INHA/KLF6/TPD52/PLCL2/LAPTM5 9 GO:0062012 regulation of small molecule metabolic process 9/445 334/18722 0.398686722836114 0.590948996066016 APOE/APOC1/CD74/TMSB4X/ANXA1/PHLDA2/FAM3C/PPARG/CDA 9 GO:0035282 segmentation 3/445 96/18722 0.400204254082945 0.592772955760719 SFRP1/BASP1/IRX2 3 GO:0042158 lipoprotein biosynthetic process 3/445 96/18722 0.400204254082945 0.592772955760719 APOE/ATG12/DBI 3 GO:0007405 neuroblast proliferation 2/445 58/18722 0.402525067013709 0.594474484471423 CTNNB1/CTNNA1 2 GO:0010574 regulation of vascular endothelial growth factor production 2/445 58/18722 0.402525067013709 0.594474484471423 NUTF2/ATF4 2 GO:0018208 peptidyl-proline modification 2/445 58/18722 0.402525067013709 0.594474484471423 P4HA1/ERO1A 2 GO:0032387 negative regulation of intracellular transport 2/445 58/18722 0.402525067013709 0.594474484471423 SP100/UBE2J1 2 GO:0032481 positive regulation of type I interferon production 2/445 58/18722 0.402525067013709 0.594474484471423 RIOK3/IRF1 2 GO:0035904 aorta development 2/445 58/18722 0.402525067013709 0.594474484471423 SOX4/LRP2 2 GO:0043666 regulation of phosphoprotein phosphatase activity 2/445 58/18722 0.402525067013709 0.594474484471423 PPP1R15A/HSP90AB1 2 GO:2000736 regulation of stem cell differentiation 2/445 58/18722 0.402525067013709 0.594474484471423 EIF2AK2/LBH 2 GO:0048771 tissue remodeling 5/445 175/18722 0.402792079892402 0.594474484471423 CA2/SFRP1/CTNNB1/SPP1/CST3 5 GO:1905475 regulation of protein localization to membrane 5/445 175/18722 0.402792079892402 0.594474484471423 GOPC/ZMYND8/GSN/GBP1/VAMP8 5 GO:0043547 positive regulation of GTPase activity 7/445 255/18722 0.403652685822799 0.595531873262136 ARHGEF5/SFRP1/ARHGAP29/FERMT2/CHN2/LIMS1/NET1 7 GO:0098876 vesicle-mediated transport to the plasma membrane 4/445 136/18722 0.405506700599418 0.59784017850685 GOPC/GOLGA4/MACF1/GOLPH3 4 GO:1903305 regulation of regulated secretory pathway 4/445 136/18722 0.405506700599418 0.59784017850685 WNT7A/RAP1B/HMOX1/VAMP8 4 GO:0007409 axonogenesis 11/445 418/18722 0.408638872006328 0.600328365193805 APOE/SKIL/WNT7A/SPP1/SEMA4C/SHTN1/GOLGA4/PAK2/HSP90AB1/MACF1/GATA3 11 GO:0001836 release of cytochrome c from mitochondria 2/445 59/18722 0.410856836629259 0.600328365193805 BNIP3/JUN 2 GO:0006767 water-soluble vitamin metabolic process 2/445 59/18722 0.410856836629259 0.600328365193805 RFK/SLC2A3 2 GO:0021885 forebrain cell migration 2/445 59/18722 0.410856836629259 0.600328365193805 CTNNB1/RHOA 2 GO:0043551 regulation of phosphatidylinositol 3-kinase activity 2/445 59/18722 0.410856836629259 0.600328365193805 KLF4/VAV2 2 GO:0048278 vesicle docking 2/445 59/18722 0.410856836629259 0.600328365193805 CTBP2/RAB8B 2 GO:0002053 positive regulation of mesenchymal cell proliferation 1/445 22/18722 0.411118117921393 0.600328365193805 CTNNB1 1 GO:0021854 hypothalamus development 1/445 22/18722 0.411118117921393 0.600328365193805 UQCRQ 1 GO:0031061 negative regulation of histone methylation 1/445 22/18722 0.411118117921393 0.600328365193805 SMARCB1 1 GO:0032693 negative regulation of interleukin-10 production 1/445 22/18722 0.411118117921393 0.600328365193805 TYROBP 1 GO:0032816 positive regulation of natural killer cell activation 1/445 22/18722 0.411118117921393 0.600328365193805 TYROBP 1 GO:0034629 cellular protein-containing complex localization 1/445 22/18722 0.411118117921393 0.600328365193805 TNFAIP2 1 GO:0035089 establishment of apical/basal cell polarity 1/445 22/18722 0.411118117921393 0.600328365193805 RHOA 1 GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation 1/445 22/18722 0.411118117921393 0.600328365193805 ANXA1 1 GO:0043486 histone exchange 1/445 22/18722 0.411118117921393 0.600328365193805 SPTY2D1 1 GO:0043574 peroxisomal transport 1/445 22/18722 0.411118117921393 0.600328365193805 RAB8B 1 GO:0045540 regulation of cholesterol biosynthetic process 1/445 22/18722 0.411118117921393 0.600328365193805 APOE 1 GO:0045663 positive regulation of myoblast differentiation 1/445 22/18722 0.411118117921393 0.600328365193805 IGFBP3 1 GO:0055093 response to hyperoxia 1/445 22/18722 0.411118117921393 0.600328365193805 BNIP3 1 GO:0060965 negative regulation of gene silencing by miRNA 1/445 22/18722 0.411118117921393 0.600328365193805 PPARG 1 GO:0071359 cellular response to dsRNA 1/445 22/18722 0.411118117921393 0.600328365193805 RIOK3 1 GO:0072574 hepatocyte proliferation 1/445 22/18722 0.411118117921393 0.600328365193805 CEBPB 1 GO:0072575 epithelial cell proliferation involved in liver morphogenesis 1/445 22/18722 0.411118117921393 0.600328365193805 CEBPB 1 GO:0099563 modification of synaptic structure 1/445 22/18722 0.411118117921393 0.600328365193805 RHOA 1 GO:0106118 regulation of sterol biosynthetic process 1/445 22/18722 0.411118117921393 0.600328365193805 APOE 1 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus 1/445 22/18722 0.411118117921393 0.600328365193805 ATF4 1 GO:1903589 positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis 1/445 22/18722 0.411118117921393 0.600328365193805 HMOX1 1 GO:0070374 positive regulation of ERK1 and ERK2 cascade 6/445 217/18722 0.412174868115565 0.601267929925835 APOE/CD74/HLA-DRB1/RAP1B/FERMT2/AKAP12 6 GO:0006333 chromatin assembly or disassembly 5/445 177/18722 0.412198203231655 0.601267929925835 TSPYL2/BRD2/SMARCB1/SPTY2D1/RSF1 5 GO:0051648 vesicle localization 5/445 177/18722 0.412198203231655 0.601267929925835 AP3S1/CTNNB1/TANC2/ARFGAP3/PDCD6 5 GO:0003333 amino acid transmembrane transport 3/445 98/18722 0.412983230388945 0.601987905693977 SLC7A1/SLC1A6/SLC7A5 3 GO:0061337 cardiac conduction 3/445 98/18722 0.412983230388945 0.601987905693977 SRI/PKP2/DSP 3 GO:0001539 cilium or flagellum-dependent cell motility 4/445 138/18722 0.416213465985333 0.606268627639426 ING2/CCSAP/TMF1/DNAJA1 4 GO:0060285 cilium-dependent cell motility 4/445 138/18722 0.416213465985333 0.606268627639426 ING2/CCSAP/TMF1/DNAJA1 4 GO:0042445 hormone metabolic process 6/445 218/18722 0.416409101511042 0.60633979497431 CGA/SPP1/HSD17B1/FDX1/TCF7L2/GATA3 6 GO:0009620 response to fungus 2/445 60/18722 0.419131078030117 0.609658620895216 S100A9/S100A8 2 GO:0019731 antibacterial humoral response 2/445 60/18722 0.419131078030117 0.609658620895216 RPL39/HLA-A 2 GO:0051965 positive regulation of synapse assembly 2/445 60/18722 0.419131078030117 0.609658620895216 WNT7A/UBE2V2 2 GO:0016570 histone modification 12/445 463/18722 0.421293027807167 0.610366570064411 CTNNB1/ING2/TAF7/IWS1/RYBP/SMARCB1/PHF14/KMT2C/MORF4L2/RTF1/BRD7/GATA3 12 GO:0030216 keratinocyte differentiation 4/445 139/18722 0.421550948212632 0.610366570064411 ANXA1/GRHL1/TXNIP/DSP 4 GO:0031503 protein-containing complex localization 6/445 220/18722 0.424866857070186 0.610366570064411 TNFAIP2/TYROBP/IWS1/RPS15/SMG1/YTHDC1 6 GO:0001759 organ induction 1/445 23/18722 0.42513161725428 0.610366570064411 CTNNB1 1 GO:0001919 regulation of receptor recycling 1/445 23/18722 0.42513161725428 0.610366570064411 CHMP5 1 GO:0002052 positive regulation of neuroblast proliferation 1/445 23/18722 0.42513161725428 0.610366570064411 CTNNB1 1 GO:0002082 regulation of oxidative phosphorylation 1/445 23/18722 0.42513161725428 0.610366570064411 RHOA 1 GO:0002363 alpha-beta T cell lineage commitment 1/445 23/18722 0.42513161725428 0.610366570064411 RHOA 1 GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin 1/445 23/18722 0.42513161725428 0.610366570064411 RHOA 1 GO:0003283 atrial septum development 1/445 23/18722 0.42513161725428 0.610366570064411 SOX4 1 GO:0006622 protein targeting to lysosome 1/445 23/18722 0.42513161725428 0.610366570064411 LAPTM5 1 GO:0006929 substrate-dependent cell migration 1/445 23/18722 0.42513161725428 0.610366570064411 SHTN1 1 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway 1/445 23/18722 0.42513161725428 0.610366570064411 CBL 1 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway 1/445 23/18722 0.42513161725428 0.610366570064411 GSTP1 1 GO:0010888 negative regulation of lipid storage 1/445 23/18722 0.42513161725428 0.610366570064411 PPARG 1 GO:0016973 poly(A)+ mRNA export from nucleus 1/445 23/18722 0.42513161725428 0.610366570064411 IWS1 1 GO:0018279 protein N-linked glycosylation via asparagine 1/445 23/18722 0.42513161725428 0.610366570064411 UBE2J1 1 GO:0021884 forebrain neuron development 1/445 23/18722 0.42513161725428 0.610366570064411 UQCRQ 1 GO:0030539 male genitalia development 1/445 23/18722 0.42513161725428 0.610366570064411 CTNNB1 1 GO:0031338 regulation of vesicle fusion 1/445 23/18722 0.42513161725428 0.610366570064411 ANXA1 1 GO:0032740 positive regulation of interleukin-17 production 1/445 23/18722 0.42513161725428 0.610366570064411 SLC7A5 1 GO:0043931 ossification involved in bone maturation 1/445 23/18722 0.42513161725428 0.610366570064411 RHOA 1 GO:0045932 negative regulation of muscle contraction 1/445 23/18722 0.42513161725428 0.610366570064411 SRI 1 GO:0045980 negative regulation of nucleotide metabolic process 1/445 23/18722 0.42513161725428 0.610366570064411 CDA 1 GO:0050765 negative regulation of phagocytosis 1/445 23/18722 0.42513161725428 0.610366570064411 PLSCR1 1 GO:0051131 chaperone-mediated protein complex assembly 1/445 23/18722 0.42513161725428 0.610366570064411 HSP90AB1 1 GO:0060143 positive regulation of syncytium formation by plasma membrane fusion 1/445 23/18722 0.42513161725428 0.610366570064411 TYROBP 1 GO:0060396 growth hormone receptor signaling pathway 1/445 23/18722 0.42513161725428 0.610366570064411 CSH1 1 GO:0060487 lung epithelial cell differentiation 1/445 23/18722 0.42513161725428 0.610366570064411 THRB 1 GO:0060575 intestinal epithelial cell differentiation 1/445 23/18722 0.42513161725428 0.610366570064411 KLF5 1 GO:0071514 genetic imprinting 1/445 23/18722 0.42513161725428 0.610366570064411 PIK3CA 1 GO:0072576 liver morphogenesis 1/445 23/18722 0.42513161725428 0.610366570064411 CEBPB 1 GO:0090335 regulation of brown fat cell differentiation 1/445 23/18722 0.42513161725428 0.610366570064411 PIM1 1 GO:1900273 positive regulation of long-term synaptic potentiation 1/445 23/18722 0.42513161725428 0.610366570064411 EIF2AK4 1 GO:2000737 negative regulation of stem cell differentiation 1/445 23/18722 0.42513161725428 0.610366570064411 LBH 1 GO:2000810 regulation of bicellular tight junction assembly 1/445 23/18722 0.42513161725428 0.610366570064411 TJP1 1 GO:2001169 regulation of ATP biosynthetic process 1/445 23/18722 0.42513161725428 0.610366570064411 TMSB4X 1 GO:0019218 regulation of steroid metabolic process 3/445 100/18722 0.425675644724175 0.610366570064411 APOE/APOC1/CGA 3 GO:0045807 positive regulation of endocytosis 3/445 100/18722 0.425675644724175 0.610366570064411 APOE/CBL/CD63 3 GO:0060079 excitatory postsynaptic potential 3/445 100/18722 0.425675644724175 0.610366570064411 WNT7A/ZMYND8/EIF4A3 3 GO:0061640 cytoskeleton-dependent cytokinesis 3/445 100/18722 0.425675644724175 0.610366570064411 RHOB/CHMP5/RHOA 3 GO:0006644 phospholipid metabolic process 10/445 383/18722 0.426485104132569 0.611315046902027 APOC1/LPCAT1/IMPA2/ISYNA1/SMG1/GDPD3/PLPP3/PLSCR1/PIK3CA/DBI 10 GO:0046165 alcohol biosynthetic process 4/445 140/18722 0.426876709169398 0.611664129579877 APOE/IMPA2/ISYNA1/PTS 4 GO:0043030 regulation of macrophage activation 2/445 61/18722 0.427345817167323 0.611699781953643 JUND/CD74 2 GO:0060997 dendritic spine morphogenesis 2/445 61/18722 0.427345817167323 0.611699781953643 WNT7A/TANC2 2 GO:1905515 non-motile cilium assembly 2/445 61/18722 0.427345817167323 0.611699781953643 TMEM107/MAP4 2 GO:0006476 protein deacetylation 3/445 101/18722 0.431986247004459 0.615111607785035 ING2/BEX4/MORF4L2 3 GO:0050830 defense response to Gram-positive bacterium 3/445 101/18722 0.431986247004459 0.615111607785035 LYZ/RPL39/HLA-A 3 GO:0002260 lymphocyte homeostasis 2/445 62/18722 0.43549920585112 0.615111607785035 CD74/SKIL 2 GO:0009116 nucleoside metabolic process 2/445 62/18722 0.43549920585112 0.615111607785035 AMD1/CDA 2 GO:0010573 vascular endothelial growth factor production 2/445 62/18722 0.43549920585112 0.615111607785035 NUTF2/ATF4 2 GO:0032613 interleukin-10 production 2/445 62/18722 0.43549920585112 0.615111607785035 HLA-DRB1/TYROBP 2 GO:0032653 regulation of interleukin-10 production 2/445 62/18722 0.43549920585112 0.615111607785035 HLA-DRB1/TYROBP 2 GO:0032731 positive regulation of interleukin-1 beta production 2/445 62/18722 0.43549920585112 0.615111607785035 NLRP2/TYROBP 2 GO:0032757 positive regulation of interleukin-8 production 2/445 62/18722 0.43549920585112 0.615111607785035 CD74/HSPA1B 2 GO:0032835 glomerulus development 2/445 62/18722 0.43549920585112 0.615111607785035 BASP1/WWTR1 2 GO:0060675 ureteric bud morphogenesis 2/445 62/18722 0.43549920585112 0.615111607785035 CTNNB1/GATA3 2 GO:0045833 negative regulation of lipid metabolic process 3/445 102/18722 0.438271517584802 0.615111607785035 APOE/APOC1/LPCAT1 3 GO:0000395 mRNA 5'-splice site recognition 1/445 24/18722 0.438812371857298 0.615111607785035 SFSWAP 1 GO:0001779 natural killer cell differentiation 1/445 24/18722 0.438812371857298 0.615111607785035 NFIL3 1 GO:0001783 B cell apoptotic process 1/445 24/18722 0.438812371857298 0.615111607785035 CD74 1 GO:0002021 response to dietary excess 1/445 24/18722 0.438812371857298 0.615111607785035 APOE 1 GO:0002438 acute inflammatory response to antigenic stimulus 1/445 24/18722 0.438812371857298 0.615111607785035 GATA3 1 GO:0002755 MyD88-dependent toll-like receptor signaling pathway 1/445 24/18722 0.438812371857298 0.615111607785035 IRF1 1 GO:0003148 outflow tract septum morphogenesis 1/445 24/18722 0.438812371857298 0.615111607785035 LRP2 1 GO:0003181 atrioventricular valve morphogenesis 1/445 24/18722 0.438812371857298 0.615111607785035 SOX4 1 GO:0006213 pyrimidine nucleoside metabolic process 1/445 24/18722 0.438812371857298 0.615111607785035 CDA 1 GO:0006817 phosphate ion transport 1/445 24/18722 0.438812371857298 0.615111607785035 CEBPB 1 GO:0010226 response to lithium ion 1/445 24/18722 0.438812371857298 0.615111607785035 CALR 1 GO:0018196 peptidyl-asparagine modification 1/445 24/18722 0.438812371857298 0.615111607785035 UBE2J1 1 GO:0021697 cerebellar cortex formation 1/445 24/18722 0.438812371857298 0.615111607785035 WNT7A 1 GO:0021801 cerebral cortex radial glia-guided migration 1/445 24/18722 0.438812371857298 0.615111607785035 CTNNB1 1 GO:0022030 telencephalon glial cell migration 1/445 24/18722 0.438812371857298 0.615111607785035 CTNNB1 1 GO:0030810 positive regulation of nucleotide biosynthetic process 1/445 24/18722 0.438812371857298 0.615111607785035 TMSB4X 1 GO:0030859 polarized epithelial cell differentiation 1/445 24/18722 0.438812371857298 0.615111607785035 RHOA 1 GO:0030878 thyroid gland development 1/445 24/18722 0.438812371857298 0.615111607785035 CGA 1 GO:0032528 microvillus organization 1/445 24/18722 0.438812371857298 0.615111607785035 KLF5 1 GO:0033032 regulation of myeloid cell apoptotic process 1/445 24/18722 0.438812371857298 0.615111607785035 ANXA1 1 GO:0035458 cellular response to interferon-beta 1/445 24/18722 0.438812371857298 0.615111607785035 IRF1 1 GO:0036010 protein localization to endosome 1/445 24/18722 0.438812371857298 0.615111607785035 RDX 1 GO:0039531 regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway 1/445 24/18722 0.438812371857298 0.615111607785035 RIOK3 1 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway 1/445 24/18722 0.438812371857298 0.615111607785035 GATA3 1 GO:0043302 positive regulation of leukocyte degranulation 1/445 24/18722 0.438812371857298 0.615111607785035 VAMP8 1 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway 1/445 24/18722 0.438812371857298 0.615111607785035 IGFBP3 1 GO:0044321 response to leptin 1/445 24/18722 0.438812371857298 0.615111607785035 LRP2 1 GO:0045649 regulation of macrophage differentiation 1/445 24/18722 0.438812371857298 0.615111607785035 INHA 1 GO:0048641 regulation of skeletal muscle tissue development 1/445 24/18722 0.438812371857298 0.615111607785035 CTNNB1 1 GO:0050687 negative regulation of defense response to virus 1/445 24/18722 0.438812371857298 0.615111607785035 RIOK3 1 GO:0050855 regulation of B cell receptor signaling pathway 1/445 24/18722 0.438812371857298 0.615111607785035 PLCL2 1 GO:0051000 positive regulation of nitric-oxide synthase activity 1/445 24/18722 0.438812371857298 0.615111607785035 APOE 1 GO:0051043 regulation of membrane protein ectodomain proteolysis 1/445 24/18722 0.438812371857298 0.615111607785035 APOE 1 GO:0051123 RNA polymerase II preinitiation complex assembly 1/445 24/18722 0.438812371857298 0.615111607785035 TAF7 1 GO:0051570 regulation of histone H3-K9 methylation 1/445 24/18722 0.438812371857298 0.615111607785035 SMARCB1 1 GO:0060149 negative regulation of posttranscriptional gene silencing 1/445 24/18722 0.438812371857298 0.615111607785035 PPARG 1 GO:0060967 negative regulation of gene silencing by RNA 1/445 24/18722 0.438812371857298 0.615111607785035 PPARG 1 GO:0061162 establishment of monopolar cell polarity 1/445 24/18722 0.438812371857298 0.615111607785035 RHOA 1 GO:0071294 cellular response to zinc ion 1/445 24/18722 0.438812371857298 0.615111607785035 MT2A 1 GO:0071378 cellular response to growth hormone stimulus 1/445 24/18722 0.438812371857298 0.615111607785035 CSH1 1 GO:0072010 glomerular epithelium development 1/445 24/18722 0.438812371857298 0.615111607785035 BASP1 1 GO:0090023 positive regulation of neutrophil chemotaxis 1/445 24/18722 0.438812371857298 0.615111607785035 CD74 1 GO:0090343 positive regulation of cell aging 1/445 24/18722 0.438812371857298 0.615111607785035 PAWR 1 GO:0098743 cell aggregation 1/445 24/18722 0.438812371857298 0.615111607785035 WNT7A 1 GO:0120255 olefinic compound biosynthetic process 1/445 24/18722 0.438812371857298 0.615111607785035 HSD17B1 1 GO:1900373 positive regulation of purine nucleotide biosynthetic process 1/445 24/18722 0.438812371857298 0.615111607785035 TMSB4X 1 GO:1901984 negative regulation of protein acetylation 1/445 24/18722 0.438812371857298 0.615111607785035 TAF7 1 GO:2000353 positive regulation of endothelial cell apoptotic process 1/445 24/18722 0.438812371857298 0.615111607785035 RGCC 1 GO:2001026 regulation of endothelial cell chemotaxis 1/445 24/18722 0.438812371857298 0.615111607785035 TMSB4X 1 GO:0006650 glycerophospholipid metabolic process 8/445 306/18722 0.442721812718741 0.620246144357065 APOC1/LPCAT1/IMPA2/SMG1/GDPD3/PLSCR1/PIK3CA/DBI 8 GO:0062013 positive regulation of small molecule metabolic process 4/445 143/18722 0.442775570009437 0.620246144357065 CD74/TMSB4X/ANXA1/PPARG 4 GO:0022617 extracellular matrix disassembly 2/445 63/18722 0.443589516907002 0.620334561388904 CST3/CTSS 2 GO:0046902 regulation of mitochondrial membrane permeability 2/445 63/18722 0.443589516907002 0.620334561388904 BNIP3/BNIP3L 2 GO:0072171 mesonephric tubule morphogenesis 2/445 63/18722 0.443589516907002 0.620334561388904 CTNNB1/GATA3 2 GO:1902373 negative regulation of mRNA catabolic process 2/445 63/18722 0.443589516907002 0.620334561388904 PKP3/YBX1 2 GO:2000242 negative regulation of reproductive process 2/445 63/18722 0.443589516907002 0.620334561388904 SERPINF1/CALR 2 GO:0014013 regulation of gliogenesis 3/445 103/18722 0.444530310365773 0.621229604912384 CTNNB1/SPINT1/LRP2 3 GO:0046425 regulation of receptor signaling pathway via JAK-STAT 3/445 103/18722 0.444530310365773 0.621229604912384 CENPJ/PARP14/CSH1 3 GO:0140013 meiotic nuclear division 5/445 185/18722 0.44955834188701 0.623466990560185 ING2/HSPA2/GOLGA2/FOXJ3/CALR 5 GO:0032412 regulation of ion transmembrane transporter activity 7/445 267/18722 0.45016885008537 0.623466990560185 TMSB4X/SRI/GOPC/HSPA2/WNK1/CTSS/NDUFA4 7 GO:0032006 regulation of TOR signaling 3/445 104/18722 0.450761518807224 0.623466990560185 PIK3CA/GOLPH3/PDCD6 3 GO:1903076 regulation of protein localization to plasma membrane 3/445 104/18722 0.450761518807224 0.623466990560185 GOPC/GBP1/VAMP8 3 GO:0030858 positive regulation of epithelial cell differentiation 2/445 64/18722 0.451615139490083 0.623466990560185 CTNNB1/VEZF1 2 GO:0050771 negative regulation of axonogenesis 2/445 64/18722 0.451615139490083 0.623466990560185 SPP1/SEMA4C 2 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus 2/445 64/18722 0.451615139490083 0.623466990560185 HLA-DRB1/SRI 2 GO:1903409 reactive oxygen species biosynthetic process 2/445 64/18722 0.451615139490083 0.623466990560185 PAGE4/RHOA 2 GO:0003071 renal system process involved in regulation of systemic arterial blood pressure 1/445 25/18722 0.452168265242874 0.623466990560185 RHOA 1 GO:0006658 phosphatidylserine metabolic process 1/445 25/18722 0.452168265242874 0.623466990560185 PLSCR1 1 GO:0010954 positive regulation of protein processing 1/445 25/18722 0.452168265242874 0.623466990560185 GSN 1 GO:0021846 cell proliferation in forebrain 1/445 25/18722 0.452168265242874 0.623466990560185 WNT7A 1 GO:0031664 regulation of lipopolysaccharide-mediated signaling pathway 1/445 25/18722 0.452168265242874 0.623466990560185 SASH1 1 GO:0032104 regulation of response to extracellular stimulus 1/445 25/18722 0.452168265242874 0.623466990560185 TRIM24 1 GO:0032107 regulation of response to nutrient levels 1/445 25/18722 0.452168265242874 0.623466990560185 TRIM24 1 GO:0035902 response to immobilization stress 1/445 25/18722 0.452168265242874 0.623466990560185 FOS 1 GO:0045324 late endosome to vacuole transport 1/445 25/18722 0.452168265242874 0.623466990560185 CHMP5 1 GO:0045822 negative regulation of heart contraction 1/445 25/18722 0.452168265242874 0.623466990560185 SRI 1 GO:0046039 GTP metabolic process 1/445 25/18722 0.452168265242874 0.623466990560185 RHOA 1 GO:0048143 astrocyte activation 1/445 25/18722 0.452168265242874 0.623466990560185 C1QA 1 GO:0050995 negative regulation of lipid catabolic process 1/445 25/18722 0.452168265242874 0.623466990560185 APOC1 1 GO:0060074 synapse maturation 1/445 25/18722 0.452168265242874 0.623466990560185 YWHAZ 1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter 1/445 25/18722 0.452168265242874 0.623466990560185 MED4 1 GO:0060740 prostate gland epithelium morphogenesis 1/445 25/18722 0.452168265242874 0.623466990560185 SFRP1 1 GO:0061339 establishment or maintenance of monopolar cell polarity 1/445 25/18722 0.452168265242874 0.623466990560185 RHOA 1 GO:0061436 establishment of skin barrier 1/445 25/18722 0.452168265242874 0.623466990560185 GRHL1 1 GO:0062009 secondary palate development 1/445 25/18722 0.452168265242874 0.623466990560185 WNT7A 1 GO:0070199 establishment of protein localization to chromosome 1/445 25/18722 0.452168265242874 0.623466990560185 CCT6A 1 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway 1/445 25/18722 0.452168265242874 0.623466990560185 HSPA1B 1 GO:0072207 metanephric epithelium development 1/445 25/18722 0.452168265242874 0.623466990560185 WWTR1 1 GO:0090312 positive regulation of protein deacetylation 1/445 25/18722 0.452168265242874 0.623466990560185 ING2 1 GO:1901623 regulation of lymphocyte chemotaxis 1/445 25/18722 0.452168265242874 0.623466990560185 WNK1 1 GO:1903792 negative regulation of anion transport 1/445 25/18722 0.452168265242874 0.623466990560185 GOPC 1 GO:1903901 negative regulation of viral life cycle 1/445 25/18722 0.452168265242874 0.623466990560185 GSN 1 GO:1903959 regulation of anion transmembrane transport 1/445 25/18722 0.452168265242874 0.623466990560185 GOPC 1 GO:1904385 cellular response to angiotensin 1/445 25/18722 0.452168265242874 0.623466990560185 CA2 1 GO:1904754 positive regulation of vascular associated smooth muscle cell migration 1/445 25/18722 0.452168265242874 0.623466990560185 ADAMTS1 1 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell 1/445 25/18722 0.452168265242874 0.623466990560185 RHOA 1 GO:1905563 negative regulation of vascular endothelial cell proliferation 1/445 25/18722 0.452168265242874 0.623466990560185 PPARG 1 GO:2000316 regulation of T-helper 17 type immune response 1/445 25/18722 0.452168265242874 0.623466990560185 NFKBIZ 1 GO:0042742 defense response to bacterium 9/445 350/18722 0.452819310841276 0.624156347375812 LYZ/CEBPB/RPL39/S100A9/S100A8/FCER1G/TMF1/HLA-A/RPS19 9 GO:0001894 tissue homeostasis 7/445 268/18722 0.454020984787342 0.625603965362412 LPCAT1/CA2/LYZ/CTNNB1/SPP1/TJP1/WWTR1 7 GO:0098657 import into cell 6/445 227/18722 0.454309822396639 0.625793223181232 SLC2A3/SLC7A1/LRP2/WNK1/SLC1A6/SLC7A5 6 GO:0016079 synaptic vesicle exocytosis 3/445 105/18722 0.456964075389463 0.6286109208904 WNT7A/RAP1B/CTBP2 3 GO:0040029 regulation of gene expression, epigenetic 3/445 105/18722 0.456964075389463 0.6286109208904 CDYL/MBD2/YTHDC1 3 GO:0062207 regulation of pattern recognition receptor signaling pathway 3/445 105/18722 0.456964075389463 0.6286109208904 RIOK3/IRF1/HSPA1B 3 GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 3/445 105/18722 0.456964075389463 0.6286109208904 CDC42EP3/ZMYND8/PIK3CA 3 GO:0033044 regulation of chromosome organization 5/445 187/18722 0.458809239783255 0.630939071086759 GNL3/CTNNB1/SMG1/HNRNPA1/CCT6A 5 GO:0003170 heart valve development 2/445 65/18722 0.459574574553006 0.631123183747358 SOX4/GATA3 2 GO:0006487 protein N-linked glycosylation 2/445 65/18722 0.459574574553006 0.631123183747358 TMEM165/UBE2J1 2 GO:0046503 glycerolipid catabolic process 2/445 65/18722 0.459574574553006 0.631123183747358 APOC1/GDPD3 2 GO:0070936 protein K48-linked ubiquitination 2/445 65/18722 0.459574574553006 0.631123183747358 GABARAP/UBE2D1 2 GO:0006766 vitamin metabolic process 3/445 106/18722 0.463136951061417 0.631123183747358 RFK/SLC2A3/LRP2 3 GO:0071887 leukocyte apoptotic process 3/445 106/18722 0.463136951061417 0.631123183747358 CD74/ANXA1/BIRC7 3 GO:0099565 chemical synaptic transmission, postsynaptic 3/445 106/18722 0.463136951061417 0.631123183747358 WNT7A/ZMYND8/EIF4A3 3 GO:0060041 retina development in camera-type eye 4/445 147/18722 0.463762346812964 0.631123183747358 LPCAT1/THRB/GNB1/SERPINF1 4 GO:0002092 positive regulation of receptor internalization 1/445 26/18722 0.465206994555968 0.631123183747358 CD63 1 GO:0002407 dendritic cell chemotaxis 1/445 26/18722 0.465206994555968 0.631123183747358 CALR 1 GO:0006517 protein deglycosylation 1/445 26/18722 0.465206994555968 0.631123183747358 MAN1A1 1 GO:0007214 gamma-aminobutyric acid signaling pathway 1/445 26/18722 0.465206994555968 0.631123183747358 PLCL2 1 GO:0009164 nucleoside catabolic process 1/445 26/18722 0.465206994555968 0.631123183747358 CDA 1 GO:0014829 vascular associated smooth muscle contraction 1/445 26/18722 0.465206994555968 0.631123183747358 RHOA 1 GO:0018027 peptidyl-lysine dimethylation 1/445 26/18722 0.465206994555968 0.631123183747358 SMARCB1 1 GO:0021680 cerebellar Purkinje cell layer development 1/445 26/18722 0.465206994555968 0.631123183747358 UQCRQ 1 GO:0032515 negative regulation of phosphoprotein phosphatase activity 1/445 26/18722 0.465206994555968 0.631123183747358 PPP1R15A 1 GO:0033522 histone H2A ubiquitination 1/445 26/18722 0.465206994555968 0.631123183747358 RYBP 1 GO:0034063 stress granule assembly 1/445 26/18722 0.465206994555968 0.631123183747358 LSM14A 1 GO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway 1/445 26/18722 0.465206994555968 0.631123183747358 HSPA1B 1 GO:0042278 purine nucleoside metabolic process 1/445 26/18722 0.465206994555968 0.631123183747358 AMD1 1 GO:0043094 cellular metabolic compound salvage 1/445 26/18722 0.465206994555968 0.631123183747358 CDA 1 GO:0046639 negative regulation of alpha-beta T cell differentiation 1/445 26/18722 0.465206994555968 0.631123183747358 ANXA1 1 GO:0046697 decidualization 1/445 26/18722 0.465206994555968 0.631123183747358 SPP1 1 GO:0046755 viral budding 1/445 26/18722 0.465206994555968 0.631123183747358 CHMP5 1 GO:0048668 collateral sprouting 1/445 26/18722 0.465206994555968 0.631123183747358 SPP1 1 GO:0048843 negative regulation of axon extension involved in axon guidance 1/445 26/18722 0.465206994555968 0.631123183747358 SEMA4C 1 GO:0051560 mitochondrial calcium ion homeostasis 1/445 26/18722 0.465206994555968 0.631123183747358 BNIP3 1 GO:0060037 pharyngeal system development 1/445 26/18722 0.465206994555968 0.631123183747358 GATA3 1 GO:0060219 camera-type eye photoreceptor cell differentiation 1/445 26/18722 0.465206994555968 0.631123183747358 THRB 1 GO:0060295 regulation of cilium movement involved in cell motility 1/445 26/18722 0.465206994555968 0.631123183747358 CCSAP 1 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity 1/445 26/18722 0.465206994555968 0.631123183747358 SRI 1 GO:0060352 cell adhesion molecule production 1/445 26/18722 0.465206994555968 0.631123183747358 GOLPH3 1 GO:0070102 interleukin-6-mediated signaling pathway 1/445 26/18722 0.465206994555968 0.631123183747358 JAK1 1 GO:0070193 synaptonemal complex organization 1/445 26/18722 0.465206994555968 0.631123183747358 HSPA2 1 GO:0070977 bone maturation 1/445 26/18722 0.465206994555968 0.631123183747358 RHOA 1 GO:0072273 metanephric nephron morphogenesis 1/445 26/18722 0.465206994555968 0.631123183747358 CTNNB1 1 GO:1902019 regulation of cilium-dependent cell motility 1/445 26/18722 0.465206994555968 0.631123183747358 CCSAP 1 GO:1903523 negative regulation of blood circulation 1/445 26/18722 0.465206994555968 0.631123183747358 SRI 1 GO:1904861 excitatory synapse assembly 1/445 26/18722 0.465206994555968 0.631123183747358 WNT7A 1 GO:2000108 positive regulation of leukocyte apoptotic process 1/445 26/18722 0.465206994555968 0.631123183747358 ANXA1 1 GO:0015711 organic anion transport 9/445 354/18722 0.466269338973286 0.632356743039607 SLC25A24/SLC16A3/ANXA1/SLC2A3/SLC7A1/LRP2/SLC1A6/SLC7A5/PSAP 9 GO:0014015 positive regulation of gliogenesis 2/445 66/18722 0.467466430462773 0.632733887366223 SPINT1/LRP2 2 GO:0042446 hormone biosynthetic process 2/445 66/18722 0.467466430462773 0.632733887366223 HSD17B1/FDX1 2 GO:0050766 positive regulation of phagocytosis 2/445 66/18722 0.467466430462773 0.632733887366223 FCER1G/CALR 2 GO:0071300 cellular response to retinoic acid 2/445 66/18722 0.467466430462773 0.632733887366223 KLF4/SERPINF1 2 GO:1905953 negative regulation of lipid localization 2/445 66/18722 0.467466430462773 0.632733887366223 APOC1/PPARG 2 GO:2000272 negative regulation of signaling receptor activity 2/445 66/18722 0.467466430462773 0.632733887366223 CBL/PPARG 2 GO:0008637 apoptotic mitochondrial changes 3/445 107/18722 0.469279154677094 0.634356082451268 BNIP3/JUN/BNIP3L 3 GO:0032526 response to retinoic acid 3/445 107/18722 0.469279154677094 0.634356082451268 KLF4/RXRA/SERPINF1 3 GO:0036503 ERAD pathway 3/445 107/18722 0.469279154677094 0.634356082451268 MAN1A1/CALR/UBE2J1 3 GO:0051341 regulation of oxidoreductase activity 3/445 107/18722 0.469279154677094 0.634356082451268 APOE/RFK/NDUFA4 3 GO:0006605 protein targeting 8/445 314/18722 0.471363809923434 0.63696561949418 HAX1/GABARAP/BNIP3L/YWHAZ/MAN1A1/CDC37/RAB8B/LAPTM5 8 GO:0046942 carboxylic acid transport 7/445 273/18722 0.473195628588126 0.638123440756781 SLC16A3/ANXA1/SLC7A1/LRP2/SLC1A6/SLC7A5/PSAP 7 GO:0035914 skeletal muscle cell differentiation 2/445 67/18722 0.475289418762006 0.638123440756781 FOS/KLF5 2 GO:0070527 platelet aggregation 2/445 67/18722 0.475289418762006 0.638123440756781 CSRP1/HBB 2 GO:0072665 protein localization to vacuole 2/445 67/18722 0.475289418762006 0.638123440756781 GBP1/LAPTM5 2 GO:1902117 positive regulation of organelle assembly 2/445 67/18722 0.475289418762006 0.638123440756781 CENPJ/RHOA 2 GO:1903317 regulation of protein maturation 2/445 67/18722 0.475289418762006 0.638123440756781 GSN/SOX4 2 GO:0000737 DNA catabolic process, endonucleolytic 1/445 27/18722 0.477936074970099 0.638123440756781 DFFB 1 GO:0001835 blastocyst hatching 1/445 27/18722 0.477936074970099 0.638123440756781 SMARCB1 1 GO:0002227 innate immune response in mucosa 1/445 27/18722 0.477936074970099 0.638123440756781 RPL39 1 GO:0002433 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis 1/445 27/18722 0.477936074970099 0.638123440756781 VAV2 1 GO:0002719 negative regulation of cytokine production involved in immune response 1/445 27/18722 0.477936074970099 0.638123440756781 HMOX1 1 GO:0002825 regulation of T-helper 1 type immune response 1/445 27/18722 0.477936074970099 0.638123440756781 ANXA1 1 GO:0003171 atrioventricular valve development 1/445 27/18722 0.477936074970099 0.638123440756781 SOX4 1 GO:0003401 axis elongation 1/445 27/18722 0.477936074970099 0.638123440756781 SFRP1 1 GO:0007263 nitric oxide mediated signal transduction 1/445 27/18722 0.477936074970099 0.638123440756781 APOE 1 GO:0008053 mitochondrial fusion 1/445 27/18722 0.477936074970099 0.638123440756781 BNIP3 1 GO:0009651 response to salt stress 1/445 27/18722 0.477936074970099 0.638123440756781 HSP90AB1 1 GO:0010758 regulation of macrophage chemotaxis 1/445 27/18722 0.477936074970099 0.638123440756781 MTUS1 1 GO:0010894 negative regulation of steroid biosynthetic process 1/445 27/18722 0.477936074970099 0.638123440756781 APOE 1 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle 1/445 27/18722 0.477936074970099 0.638123440756781 HSPA2 1 GO:0015813 L-glutamate transmembrane transport 1/445 27/18722 0.477936074970099 0.638123440756781 SLC1A6 1 GO:0032781 positive regulation of ATPase activity 1/445 27/18722 0.477936074970099 0.638123440756781 TPM1 1 GO:0033561 regulation of water loss via skin 1/445 27/18722 0.477936074970099 0.638123440756781 GRHL1 1 GO:0035188 hatching 1/445 27/18722 0.477936074970099 0.638123440756781 SMARCB1 1 GO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis 1/445 27/18722 0.477936074970099 0.638123440756781 VAV2 1 GO:0039529 RIG-I signaling pathway 1/445 27/18722 0.477936074970099 0.638123440756781 LSM14A 1 GO:0042402 cellular biogenic amine catabolic process 1/445 27/18722 0.477936074970099 0.638123440756781 SAT1 1 GO:0046174 polyol catabolic process 1/445 27/18722 0.477936074970099 0.638123440756781 IMPA2 1 GO:0060142 regulation of syncytium formation by plasma membrane fusion 1/445 27/18722 0.477936074970099 0.638123440756781 TYROBP 1 GO:0060512 prostate gland morphogenesis 1/445 27/18722 0.477936074970099 0.638123440756781 SFRP1 1 GO:0070861 regulation of protein exit from endoplasmic reticulum 1/445 27/18722 0.477936074970099 0.638123440756781 UBE2J1 1 GO:0071624 positive regulation of granulocyte chemotaxis 1/445 27/18722 0.477936074970099 0.638123440756781 CD74 1 GO:0071684 organism emergence from protective structure 1/445 27/18722 0.477936074970099 0.638123440756781 SMARCB1 1 GO:1900746 regulation of vascular endothelial growth factor signaling pathway 1/445 27/18722 0.477936074970099 0.638123440756781 CD63 1 GO:1903205 regulation of hydrogen peroxide-induced cell death 1/445 27/18722 0.477936074970099 0.638123440756781 PAWR 1 GO:1904357 negative regulation of telomere maintenance via telomere lengthening 1/445 27/18722 0.477936074970099 0.638123440756781 HNRNPA1 1 GO:2000463 positive regulation of excitatory postsynaptic potential 1/445 27/18722 0.477936074970099 0.638123440756781 WNT7A 1 GO:0034766 negative regulation of ion transmembrane transport 3/445 109/18722 0.481467767227726 0.642631129698784 SRI/GOPC/SESTD1 3 GO:0010812 negative regulation of cell-substrate adhesion 2/445 68/18722 0.483042350070273 0.643277868517182 GBP1/RHOA 2 GO:0031640 killing of cells of other organism 2/445 68/18722 0.483042350070273 0.643277868517182 LYZ/RPS19 2 GO:0032922 circadian regulation of gene expression 2/445 68/18722 0.483042350070273 0.643277868517182 ATF4/NRIP1 2 GO:0042267 natural killer cell mediated cytotoxicity 2/445 68/18722 0.483042350070273 0.643277868517182 HLA-B/HLA-A 2 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 2/445 68/18722 0.483042350070273 0.643277868517182 PARP14/CSH1 2 GO:0051926 negative regulation of calcium ion transport 2/445 68/18722 0.483042350070273 0.643277868517182 SRI/SESTD1 2 GO:0060411 cardiac septum morphogenesis 2/445 68/18722 0.483042350070273 0.643277868517182 SOX4/LRP2 2 GO:0031497 chromatin assembly 4/445 151/18722 0.484465169339228 0.644964748482227 TSPYL2/BRD2/SPTY2D1/RSF1 4 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 5/445 193/18722 0.486279753654299 0.645188218182944 CD74/HAX1/PAK2/PARP14/CSH1 5 GO:0003014 renal system process 3/445 110/18722 0.487512378184703 0.645188218182944 GSN/HBB/RHOA 3 GO:0030317 flagellated sperm motility 3/445 110/18722 0.487512378184703 0.645188218182944 ING2/TMF1/DNAJA1 3 GO:0032611 interleukin-1 beta production 3/445 110/18722 0.487512378184703 0.645188218182944 NLRP2/TYROBP/GSTP1 3 GO:0032651 regulation of interleukin-1 beta production 3/445 110/18722 0.487512378184703 0.645188218182944 NLRP2/TYROBP/GSTP1 3 GO:0048259 regulation of receptor-mediated endocytosis 3/445 110/18722 0.487512378184703 0.645188218182944 APOC1/CBL/CD63 3 GO:0097722 sperm motility 3/445 110/18722 0.487512378184703 0.645188218182944 ING2/TMF1/DNAJA1 3 GO:0000423 mitophagy 1/445 28/18722 0.490362843979904 0.645188218182944 CDC37 1 GO:0000470 maturation of LSU-rRNA 1/445 28/18722 0.490362843979904 0.645188218182944 ZNHIT6 1 GO:0002507 tolerance induction 1/445 28/18722 0.490362843979904 0.645188218182944 HLA-B 1 GO:0003156 regulation of animal organ formation 1/445 28/18722 0.490362843979904 0.645188218182944 CTNNB1 1 GO:0007271 synaptic transmission, cholinergic 1/445 28/18722 0.490362843979904 0.645188218182944 APOE 1 GO:0010460 positive regulation of heart rate 1/445 28/18722 0.490362843979904 0.645188218182944 TPM1 1 GO:0010464 regulation of mesenchymal cell proliferation 1/445 28/18722 0.490362843979904 0.645188218182944 CTNNB1 1 GO:0010575 positive regulation of vascular endothelial growth factor production 1/445 28/18722 0.490362843979904 0.645188218182944 ATF4 1 GO:0010818 T cell chemotaxis 1/445 28/18722 0.490362843979904 0.645188218182944 WNK1 1 GO:0015740 C4-dicarboxylate transport 1/445 28/18722 0.490362843979904 0.645188218182944 SLC1A6 1 GO:0030262 apoptotic nuclear changes 1/445 28/18722 0.490362843979904 0.645188218182944 DFFB 1 GO:0031440 regulation of mRNA 3'-end processing 1/445 28/18722 0.490362843979904 0.645188218182944 YTHDC1 1 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway 1/445 28/18722 0.490362843979904 0.645188218182944 CBL 1 GO:0042983 amyloid precursor protein biosynthetic process 1/445 28/18722 0.490362843979904 0.645188218182944 PAWR 1 GO:0042984 regulation of amyloid precursor protein biosynthetic process 1/445 28/18722 0.490362843979904 0.645188218182944 PAWR 1 GO:0045686 negative regulation of glial cell differentiation 1/445 28/18722 0.490362843979904 0.645188218182944 CTNNB1 1 GO:0046426 negative regulation of receptor signaling pathway via JAK-STAT 1/445 28/18722 0.490362843979904 0.645188218182944 PARP14 1 GO:0051503 adenine nucleotide transport 1/445 28/18722 0.490362843979904 0.645188218182944 SLC25A24 1 GO:0060259 regulation of feeding behavior 1/445 28/18722 0.490362843979904 0.645188218182944 EIF2AK4 1 GO:0060325 face morphogenesis 1/445 28/18722 0.490362843979904 0.645188218182944 ANKRD11 1 GO:0060765 regulation of androgen receptor signaling pathway 1/445 28/18722 0.490362843979904 0.645188218182944 SFRP1 1 GO:0071280 cellular response to copper ion 1/445 28/18722 0.490362843979904 0.645188218182944 MT2A 1 GO:0080111 DNA demethylation 1/445 28/18722 0.490362843979904 0.645188218182944 GATA3 1 GO:0090200 positive regulation of release of cytochrome c from mitochondria 1/445 28/18722 0.490362843979904 0.645188218182944 BNIP3 1 GO:1902624 positive regulation of neutrophil migration 1/445 28/18722 0.490362843979904 0.645188218182944 CD74 1 GO:1903649 regulation of cytoplasmic transport 1/445 28/18722 0.490362843979904 0.645188218182944 RDX 1 GO:1903671 negative regulation of sprouting angiogenesis 1/445 28/18722 0.490362843979904 0.645188218182944 EPN2 1 GO:1904046 negative regulation of vascular endothelial growth factor production 1/445 28/18722 0.490362843979904 0.645188218182944 NUTF2 1 GO:1990776 response to angiotensin 1/445 28/18722 0.490362843979904 0.645188218182944 CA2 1 GO:0006368 transcription elongation from RNA polymerase II promoter 2/445 69/18722 0.490724130121233 0.645188218182944 CTNNB1/RTF1 2 GO:0050688 regulation of defense response to virus 2/445 69/18722 0.490724130121233 0.645188218182944 RIOK3/EIF2AK4 2 GO:0050810 regulation of steroid biosynthetic process 2/445 69/18722 0.490724130121233 0.645188218182944 APOE/CGA 2 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling 3/445 111/18722 0.493522719939381 0.648661265055546 KLF4/HAX1/CBL 3 GO:0035601 protein deacylation 3/445 112/18722 0.499497982091645 0.653179558641693 ING2/BEX4/MORF4L2 3 GO:0032259 methylation 9/445 364/18722 0.499591018713385 0.653179558641693 FOS/CTNNB1/IWS1/SMARCB1/MBD2/KMT2C/PIK3CA/RTF1/GATA3 9 GO:0021700 developmental maturation 7/445 280/18722 0.49974266440435 0.653179558641693 CTNNB1/YWHAZ/CD63/C1QA/PPARG/RHOA/GATA3 7 GO:0051259 protein complex oligomerization 6/445 238/18722 0.499803264459228 0.653179558641693 CD74/STK3/ZNHIT6/HLA-DRB1/RNF213/GOLGA2 6 GO:0045664 regulation of neuron differentiation 5/445 196/18722 0.499832169188588 0.653179558641693 SFRP1/CPNE1/EIF2AK4/CALR/RHOA 5 GO:0002360 T cell lineage commitment 1/445 29/18722 0.502494465592665 0.653179558641693 RHOA 1 GO:0003209 cardiac atrium morphogenesis 1/445 29/18722 0.502494465592665 0.653179558641693 SOX4 1 GO:0006656 phosphatidylcholine biosynthetic process 1/445 29/18722 0.502494465592665 0.653179558641693 LPCAT1 1 GO:0009310 amine catabolic process 1/445 29/18722 0.502494465592665 0.653179558641693 SAT1 1 GO:0010390 histone monoubiquitination 1/445 29/18722 0.502494465592665 0.653179558641693 RYBP 1 GO:0010592 positive regulation of lamellipodium assembly 1/445 29/18722 0.502494465592665 0.653179558641693 PIK3CA 1 GO:0015868 purine ribonucleotide transport 1/445 29/18722 0.502494465592665 0.653179558641693 SLC25A24 1 GO:0019082 viral protein processing 1/445 29/18722 0.502494465592665 0.653179558641693 GALNT1 1 GO:0022011 myelination in peripheral nervous system 1/445 29/18722 0.502494465592665 0.653179558641693 NDRG1 1 GO:0030970 retrograde protein transport, ER to cytosol 1/445 29/18722 0.502494465592665 0.653179558641693 UBE2J1 1 GO:0031069 hair follicle morphogenesis 1/445 29/18722 0.502494465592665 0.653179558641693 CTNNB1 1 GO:0032292 peripheral nervous system axon ensheathment 1/445 29/18722 0.502494465592665 0.653179558641693 NDRG1 1 GO:0032372 negative regulation of sterol transport 1/445 29/18722 0.502494465592665 0.653179558641693 APOC1 1 GO:0032375 negative regulation of cholesterol transport 1/445 29/18722 0.502494465592665 0.653179558641693 APOC1 1 GO:0033028 myeloid cell apoptotic process 1/445 29/18722 0.502494465592665 0.653179558641693 ANXA1 1 GO:0034067 protein localization to Golgi apparatus 1/445 29/18722 0.502494465592665 0.653179558641693 GOLPH3 1 GO:0042759 long-chain fatty acid biosynthetic process 1/445 29/18722 0.502494465592665 0.653179558641693 GSTP1 1 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity 1/445 29/18722 0.502494465592665 0.653179558641693 RGCC 1 GO:0060441 epithelial tube branching involved in lung morphogenesis 1/445 29/18722 0.502494465592665 0.653179558641693 CTNNB1 1 GO:0060969 negative regulation of gene silencing 1/445 29/18722 0.502494465592665 0.653179558641693 PPARG 1 GO:0071549 cellular response to dexamethasone stimulus 1/445 29/18722 0.502494465592665 0.653179558641693 SERPINF1 1 GO:0072539 T-helper 17 cell differentiation 1/445 29/18722 0.502494465592665 0.653179558641693 NFKBIZ 1 GO:0090025 regulation of monocyte chemotaxis 1/445 29/18722 0.502494465592665 0.653179558641693 AIF1 1 GO:0090114 COPII-coated vesicle budding 1/445 29/18722 0.502494465592665 0.653179558641693 PDCD6 1 GO:0095500 acetylcholine receptor signaling pathway 1/445 29/18722 0.502494465592665 0.653179558641693 GNB1 1 GO:1900117 regulation of execution phase of apoptosis 1/445 29/18722 0.502494465592665 0.653179558641693 PAK2 1 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 1/445 29/18722 0.502494465592665 0.653179558641693 MCL1 1 GO:1902430 negative regulation of amyloid-beta formation 1/445 29/18722 0.502494465592665 0.653179558641693 APOE 1 GO:1902547 regulation of cellular response to vascular endothelial growth factor stimulus 1/445 29/18722 0.502494465592665 0.653179558641693 CD63 1 GO:1903513 endoplasmic reticulum to cytosol transport 1/445 29/18722 0.502494465592665 0.653179558641693 UBE2J1 1 GO:0031623 receptor internalization 3/445 113/18722 0.505437388584548 0.656328599017995 FCER1G/CD63/GRB2 3 GO:0044344 cellular response to fibroblast growth factor stimulus 3/445 113/18722 0.505437388584548 0.656328599017995 SFRP1/CTNNB1/GATA3 3 GO:0002228 natural killer cell mediated immunity 2/445 71/18722 0.505870312097142 0.656328599017995 HLA-B/HLA-A 2 GO:0043550 regulation of lipid kinase activity 2/445 71/18722 0.505870312097142 0.656328599017995 KLF4/VAV2 2 GO:0050795 regulation of behavior 2/445 71/18722 0.505870312097142 0.656328599017995 APOE/EIF2AK4 2 GO:0061515 myeloid cell development 2/445 71/18722 0.505870312097142 0.656328599017995 TYROBP/TMOD3 2 GO:0048167 regulation of synaptic plasticity 5/445 198/18722 0.508791042734385 0.659910768457062 APOE/TYROBP/EIF2AK4/PLK2/ATF4 5 GO:0021987 cerebral cortex development 3/445 114/18722 0.511340197090213 0.660469383616368 CTNNB1/BNIP3/RHOA 3 GO:0006323 DNA packaging 5/445 199/18722 0.513246379428128 0.660469383616368 TSPYL2/DFFB/BRD2/SPTY2D1/RSF1 5 GO:0005977 glycogen metabolic process 2/445 72/18722 0.513332967214189 0.660469383616368 PHLDA2/RB1CC1 2 GO:0033627 cell adhesion mediated by integrin 2/445 72/18722 0.513332967214189 0.660469383616368 WNK1/PLPP3 2 GO:0070227 lymphocyte apoptotic process 2/445 72/18722 0.513332967214189 0.660469383616368 CD74/BIRC7 2 GO:0006921 cellular component disassembly involved in execution phase of apoptosis 1/445 30/18722 0.514337934421171 0.660469383616368 DFFB 1 GO:0007176 regulation of epidermal growth factor-activated receptor activity 1/445 30/18722 0.514337934421171 0.660469383616368 CBL 1 GO:0008209 androgen metabolic process 1/445 30/18722 0.514337934421171 0.660469383616368 SPP1 1 GO:0010453 regulation of cell fate commitment 1/445 30/18722 0.514337934421171 0.660469383616368 LMO4 1 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 1/445 30/18722 0.514337934421171 0.660469383616368 SRI 1 GO:0015865 purine nucleotide transport 1/445 30/18722 0.514337934421171 0.660469383616368 SLC25A24 1 GO:0019674 NAD metabolic process 1/445 30/18722 0.514337934421171 0.660469383616368 LDHA 1 GO:0031365 N-terminal protein amino acid modification 1/445 30/18722 0.514337934421171 0.660469383616368 SOX4 1 GO:0034390 smooth muscle cell apoptotic process 1/445 30/18722 0.514337934421171 0.660469383616368 PPARG 1 GO:0034391 regulation of smooth muscle cell apoptotic process 1/445 30/18722 0.514337934421171 0.660469383616368 PPARG 1 GO:0036258 multivesicular body assembly 1/445 30/18722 0.514337934421171 0.660469383616368 CHMP5 1 GO:0036296 response to increased oxygen levels 1/445 30/18722 0.514337934421171 0.660469383616368 BNIP3 1 GO:0043032 positive regulation of macrophage activation 1/445 30/18722 0.514337934421171 0.660469383616368 JUND 1 GO:0045939 negative regulation of steroid metabolic process 1/445 30/18722 0.514337934421171 0.660469383616368 APOE 1 GO:0051125 regulation of actin nucleation 1/445 30/18722 0.514337934421171 0.660469383616368 GSN 1 GO:0051491 positive regulation of filopodium assembly 1/445 30/18722 0.514337934421171 0.660469383616368 ZMYND8 1 GO:0060292 long-term synaptic depression 1/445 30/18722 0.514337934421171 0.660469383616368 PLK2 1 GO:0060674 placenta blood vessel development 1/445 30/18722 0.514337934421171 0.660469383616368 SPINT1 1 GO:0061311 cell surface receptor signaling pathway involved in heart development 1/445 30/18722 0.514337934421171 0.660469383616368 CTNNB1 1 GO:0070168 negative regulation of biomineral tissue development 1/445 30/18722 0.514337934421171 0.660469383616368 SRGN 1 GO:0070229 negative regulation of lymphocyte apoptotic process 1/445 30/18722 0.514337934421171 0.660469383616368 CD74 1 GO:0099068 postsynapse assembly 1/445 30/18722 0.514337934421171 0.660469383616368 WNT7A 1 GO:1900101 regulation of endoplasmic reticulum unfolded protein response 1/445 30/18722 0.514337934421171 0.660469383616368 PPP1R15A 1 GO:1902751 positive regulation of cell cycle G2/M phase transition 1/445 30/18722 0.514337934421171 0.660469383616368 HSPA2 1 GO:1903019 negative regulation of glycoprotein metabolic process 1/445 30/18722 0.514337934421171 0.660469383616368 CST3 1 GO:1903579 negative regulation of ATP metabolic process 1/445 30/18722 0.514337934421171 0.660469383616368 RHOA 1 GO:2000648 positive regulation of stem cell proliferation 1/445 30/18722 0.514337934421171 0.660469383616368 FERMT2 1 GO:0000077 DNA damage checkpoint signaling 3/445 115/18722 0.517205698392354 0.663945537619271 SOX4/EIF2AK4/PLK2 3 GO:0048562 embryonic organ morphogenesis 7/445 285/18722 0.518442622999451 0.665326646663787 MTHFD1L/OSR2/FBN2/CTNNB1/EFEMP1/EIF4A3/GATA3 7 GO:0006073 cellular glucan metabolic process 2/445 73/18722 0.520720970418929 0.666593842206568 PHLDA2/RB1CC1 2 GO:0032732 positive regulation of interleukin-1 production 2/445 73/18722 0.520720970418929 0.666593842206568 NLRP2/TYROBP 2 GO:0035773 insulin secretion involved in cellular response to glucose stimulus 2/445 73/18722 0.520720970418929 0.666593842206568 HLA-DRB1/SRI 2 GO:0044042 glucan metabolic process 2/445 73/18722 0.520720970418929 0.666593842206568 PHLDA2/RB1CC1 2 GO:0051865 protein autoubiquitination 2/445 73/18722 0.520720970418929 0.666593842206568 RNF213/SASH1 2 GO:0061035 regulation of cartilage development 2/445 73/18722 0.520720970418929 0.666593842206568 CTNNB1/EFEMP1 2 GO:0099518 vesicle cytoskeletal trafficking 2/445 73/18722 0.520720970418929 0.666593842206568 AP3S1/TANC2 2 GO:1904427 positive regulation of calcium ion transmembrane transport 2/445 73/18722 0.520720970418929 0.666593842206568 SRI/HSPA2 2 GO:0043200 response to amino acid 3/445 116/18722 0.523033215766221 0.668459455125872 CEBPB/GSTP1/RHOA 3 GO:0098732 macromolecule deacylation 3/445 116/18722 0.523033215766221 0.668459455125872 ING2/BEX4/MORF4L2 3 GO:0001782 B cell homeostasis 1/445 31/18722 0.525900079680243 0.668459455125872 CD74 1 GO:0002230 positive regulation of defense response to virus by host 1/445 31/18722 0.525900079680243 0.668459455125872 EIF2AK4 1 GO:0030212 hyaluronan metabolic process 1/445 31/18722 0.525900079680243 0.668459455125872 PIM1 1 GO:0031063 regulation of histone deacetylation 1/445 31/18722 0.525900079680243 0.668459455125872 ING2 1 GO:0032509 endosome transport via multivesicular body sorting pathway 1/445 31/18722 0.525900079680243 0.668459455125872 CHMP5 1 GO:0034656 nucleobase-containing small molecule catabolic process 1/445 31/18722 0.525900079680243 0.668459455125872 CDA 1 GO:0035510 DNA dealkylation 1/445 31/18722 0.525900079680243 0.668459455125872 GATA3 1 GO:0036257 multivesicular body organization 1/445 31/18722 0.525900079680243 0.668459455125872 CHMP5 1 GO:0036474 cell death in response to hydrogen peroxide 1/445 31/18722 0.525900079680243 0.668459455125872 PAWR 1 GO:0045987 positive regulation of smooth muscle contraction 1/445 31/18722 0.525900079680243 0.668459455125872 RHOA 1 GO:0050482 arachidonic acid secretion 1/445 31/18722 0.525900079680243 0.668459455125872 ANXA1 1 GO:0060045 positive regulation of cardiac muscle cell proliferation 1/445 31/18722 0.525900079680243 0.668459455125872 PIM1 1 GO:0070633 transepithelial transport 1/445 31/18722 0.525900079680243 0.668459455125872 CLDN19 1 GO:0071711 basement membrane organization 1/445 31/18722 0.525900079680243 0.668459455125872 CTSS 1 GO:0097106 postsynaptic density organization 1/445 31/18722 0.525900079680243 0.668459455125872 ZMYND8 1 GO:0110150 negative regulation of biomineralization 1/445 31/18722 0.525900079680243 0.668459455125872 SRGN 1 GO:1900027 regulation of ruffle assembly 1/445 31/18722 0.525900079680243 0.668459455125872 RDX 1 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 1/445 31/18722 0.525900079680243 0.668459455125872 HMOX1 1 GO:1903963 arachidonate transport 1/445 31/18722 0.525900079680243 0.668459455125872 ANXA1 1 GO:1905144 response to acetylcholine 1/445 31/18722 0.525900079680243 0.668459455125872 GNB1 1 GO:1905145 cellular response to acetylcholine 1/445 31/18722 0.525900079680243 0.668459455125872 GNB1 1 GO:0032388 positive regulation of intracellular transport 5/445 202/18722 0.526511133977006 0.668824567791824 NUTF2/HSP90AB1/KHDRBS1/RDX/TCF7L2 5 GO:1903046 meiotic cell cycle process 5/445 202/18722 0.526511133977006 0.668824567791824 ING2/HSPA2/GOLGA2/FOXJ3/CALR 5 GO:0003151 outflow tract morphogenesis 2/445 74/18722 0.528033648044793 0.669934582332015 CTNNB1/LRP2 2 GO:0006801 superoxide metabolic process 2/445 74/18722 0.528033648044793 0.669934582332015 TYROBP/GSTP1 2 GO:0051881 regulation of mitochondrial membrane potential 2/445 74/18722 0.528033648044793 0.669934582332015 BNIP3/BNIP3L 2 GO:0070972 protein localization to endoplasmic reticulum 2/445 74/18722 0.528033648044793 0.669934582332015 PPP1R15A/MAN1A1 2 GO:0035637 multicellular organismal signaling 4/445 160/18722 0.52979985524383 0.671762799880989 SRI/PKP2/CLDN19/DSP 4 GO:0043271 negative regulation of ion transport 4/445 160/18722 0.52979985524383 0.671762799880989 SRI/GOPC/SESTD1/WNK1 4 GO:0060541 respiratory system development 5/445 203/18722 0.530897674323728 0.672948233394084 CTNNB1/YWHAZ/BASP1/THRB/SPARC 5 GO:0006094 gluconeogenesis 2/445 75/18722 0.53527040039198 0.675943298174648 FAM3C/ATF4 2 GO:0051453 regulation of intracellular pH 2/445 75/18722 0.53527040039198 0.675943298174648 CA2/TMEM165 2 GO:1902369 negative regulation of RNA catabolic process 2/445 75/18722 0.53527040039198 0.675943298174648 PKP3/YBX1 2 GO:2001259 positive regulation of cation channel activity 2/445 75/18722 0.53527040039198 0.675943298174648 TMSB4X/CTSS 2 GO:0003180 aortic valve morphogenesis 1/445 32/18722 0.537187569089172 0.675943298174648 GATA3 1 GO:0006308 DNA catabolic process 1/445 32/18722 0.537187569089172 0.675943298174648 DFFB 1 GO:0008156 negative regulation of DNA replication 1/445 32/18722 0.537187569089172 0.675943298174648 TSPYL2 1 GO:0010743 regulation of macrophage derived foam cell differentiation 1/445 32/18722 0.537187569089172 0.675943298174648 PPARG 1 GO:0014044 Schwann cell development 1/445 32/18722 0.537187569089172 0.675943298174648 NDRG1 1 GO:0019835 cytolysis 1/445 32/18722 0.537187569089172 0.675943298174648 LYZ 1 GO:0019934 cGMP-mediated signaling 1/445 32/18722 0.537187569089172 0.675943298174648 APOE 1 GO:0021799 cerebral cortex radially oriented cell migration 1/445 32/18722 0.537187569089172 0.675943298174648 CTNNB1 1 GO:0030431 sleep 1/445 32/18722 0.537187569089172 0.675943298174648 FOS 1 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter 1/445 32/18722 0.537187569089172 0.675943298174648 CTNNB1 1 GO:0035767 endothelial cell chemotaxis 1/445 32/18722 0.537187569089172 0.675943298174648 TMSB4X 1 GO:0048841 regulation of axon extension involved in axon guidance 1/445 32/18722 0.537187569089172 0.675943298174648 SEMA4C 1 GO:0050850 positive regulation of calcium-mediated signaling 1/445 32/18722 0.537187569089172 0.675943298174648 CAMTA1 1 GO:0060323 head morphogenesis 1/445 32/18722 0.537187569089172 0.675943298174648 ANKRD11 1 GO:0072337 modified amino acid transport 1/445 32/18722 0.537187569089172 0.675943298174648 LRP2 1 GO:0090022 regulation of neutrophil chemotaxis 1/445 32/18722 0.537187569089172 0.675943298174648 CD74 1 GO:1900745 positive regulation of p38MAPK cascade 1/445 32/18722 0.537187569089172 0.675943298174648 SASH1 1 GO:1901185 negative regulation of ERBB signaling pathway 1/445 32/18722 0.537187569089172 0.675943298174648 CBL 1 GO:1901532 regulation of hematopoietic progenitor cell differentiation 1/445 32/18722 0.537187569089172 0.675943298174648 EIF2AK2 1 GO:2000515 negative regulation of CD4-positive, alpha-beta T cell activation 1/445 32/18722 0.537187569089172 0.675943298174648 ANXA1 1 GO:0045685 regulation of glial cell differentiation 2/445 76/18722 0.542430698606471 0.681917594626698 CTNNB1/SPINT1 2 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator 2/445 76/18722 0.542430698606471 0.681917594626698 CD74/ING2 2 GO:0086001 cardiac muscle cell action potential 2/445 76/18722 0.542430698606471 0.681917594626698 PKP2/DSP 2 GO:0008016 regulation of heart contraction 5/445 206/18722 0.543946999346594 0.683562558493972 TPM1/SRI/THRB/PKP2/DSP 5 GO:0006633 fatty acid biosynthetic process 4/445 163/18722 0.544475591485967 0.683562558493972 APOC1/CD74/ANXA1/GSTP1 4 GO:0010976 positive regulation of neuron projection development 4/445 163/18722 0.544475591485967 0.683562558493972 APOE/S100A9/UBE2V2/SERPINF1 4 GO:0072655 establishment of protein localization to mitochondrion 3/445 120/18722 0.545951013839287 0.683562558493972 HAX1/BNIP3L/DNAJA1 3 GO:0001881 receptor recycling 1/445 33/18722 0.548206912682287 0.683562558493972 CHMP5 1 GO:0002335 mature B cell differentiation 1/445 33/18722 0.548206912682287 0.683562558493972 PLCL2 1 GO:0006654 phosphatidic acid biosynthetic process 1/445 33/18722 0.548206912682287 0.683562558493972 LPCAT1 1 GO:0009156 ribonucleoside monophosphate biosynthetic process 1/445 33/18722 0.548206912682287 0.683562558493972 RFK 1 GO:0010984 regulation of lipoprotein particle clearance 1/445 33/18722 0.548206912682287 0.683562558493972 APOC1 1 GO:0021696 cerebellar cortex morphogenesis 1/445 33/18722 0.548206912682287 0.683562558493972 WNT7A 1 GO:0031116 positive regulation of microtubule polymerization 1/445 33/18722 0.548206912682287 0.683562558493972 HSPA1B 1 GO:0032228 regulation of synaptic transmission, GABAergic 1/445 33/18722 0.548206912682287 0.683562558493972 PLCL2 1 GO:0035025 positive regulation of Rho protein signal transduction 1/445 33/18722 0.548206912682287 0.683562558493972 NET1 1 GO:0036336 dendritic cell migration 1/445 33/18722 0.548206912682287 0.683562558493972 CALR 1 GO:0040020 regulation of meiotic nuclear division 1/445 33/18722 0.548206912682287 0.683562558493972 CALR 1 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 1/445 33/18722 0.548206912682287 0.683562558493972 VAV2 1 GO:0045648 positive regulation of erythrocyte differentiation 1/445 33/18722 0.548206912682287 0.683562558493972 HSPA1B 1 GO:0048333 mesodermal cell differentiation 1/445 33/18722 0.548206912682287 0.683562558493972 KLF4 1 GO:0050901 leukocyte tethering or rolling 1/445 33/18722 0.548206912682287 0.683562558493972 GOLPH3 1 GO:0060260 regulation of transcription initiation from RNA polymerase II promoter 1/445 33/18722 0.548206912682287 0.683562558493972 MED4 1 GO:0099084 postsynaptic specialization organization 1/445 33/18722 0.548206912682287 0.683562558493972 ZMYND8 1 GO:0099174 regulation of presynapse organization 1/445 33/18722 0.548206912682287 0.683562558493972 WNT7A 1 GO:1900181 negative regulation of protein localization to nucleus 1/445 33/18722 0.548206912682287 0.683562558493972 CTNNA1 1 GO:1902275 regulation of chromatin organization 1/445 33/18722 0.548206912682287 0.683562558493972 SPTY2D1 1 GO:1902992 negative regulation of amyloid precursor protein catabolic process 1/445 33/18722 0.548206912682287 0.683562558493972 APOE 1 GO:1905606 regulation of presynapse assembly 1/445 33/18722 0.548206912682287 0.683562558493972 WNT7A 1 GO:2000036 regulation of stem cell population maintenance 1/445 33/18722 0.548206912682287 0.683562558493972 LBH 1 GO:0050806 positive regulation of synaptic transmission 4/445 164/18722 0.549314965489082 0.684572578817352 APOE/TYROBP/EIF2AK4/PLK2 4 GO:0006367 transcription initiation from RNA polymerase II promoter 2/445 77/18722 0.549514081665054 0.684572578817352 MED4/TAF7 2 GO:0021675 nerve development 2/445 77/18722 0.549514081665054 0.684572578817352 CTNNB1/NAV2 2 GO:0010948 negative regulation of cell cycle process 7/445 294/18722 0.551434915424808 0.686758406879675 KLF4/SOX4/EIF2AK4/PLK2/BRD7/RGCC/WEE1 7 GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway 2/445 78/18722 0.556520153463116 0.691549030019362 AKAP12/PSAP 2 GO:0008306 associative learning 2/445 78/18722 0.556520153463116 0.691549030019362 FOS/EIF4A3 2 GO:0019319 hexose biosynthetic process 2/445 78/18722 0.556520153463116 0.691549030019362 FAM3C/ATF4 2 GO:0034637 cellular carbohydrate biosynthetic process 2/445 78/18722 0.556520153463116 0.691549030019362 IMPA2/ISYNA1 2 GO:0061045 negative regulation of wound healing 2/445 78/18722 0.556520153463116 0.691549030019362 APOE/CLDN19 2 GO:1901616 organic hydroxy compound catabolic process 2/445 78/18722 0.556520153463116 0.691549030019362 APOE/IMPA2 2 GO:0051208 sequestering of calcium ion 3/445 122/18722 0.557166698010971 0.691549030019362 SRI/ERO1A/CALR 3 GO:0001662 behavioral fear response 1/445 34/18722 0.558964466529811 0.691549030019362 APOE 1 GO:0009112 nucleobase metabolic process 1/445 34/18722 0.558964466529811 0.691549030019362 CDA 1 GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 1/445 34/18722 0.558964466529811 0.691549030019362 SRI 1 GO:0030851 granulocyte differentiation 1/445 34/18722 0.558964466529811 0.691549030019362 HAX1 1 GO:0031128 developmental induction 1/445 34/18722 0.558964466529811 0.691549030019362 CTNNB1 1 GO:0032743 positive regulation of interleukin-2 production 1/445 34/18722 0.558964466529811 0.691549030019362 ANXA1 1 GO:0032770 positive regulation of monooxygenase activity 1/445 34/18722 0.558964466529811 0.691549030019362 APOE 1 GO:0034383 low-density lipoprotein particle clearance 1/445 34/18722 0.558964466529811 0.691549030019362 HMOX1 1 GO:0035308 negative regulation of protein dephosphorylation 1/445 34/18722 0.558964466529811 0.691549030019362 PPP1R15A 1 GO:0035909 aorta morphogenesis 1/445 34/18722 0.558964466529811 0.691549030019362 SOX4 1 GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 1/445 34/18722 0.558964466529811 0.691549030019362 CD74 1 GO:0048261 negative regulation of receptor-mediated endocytosis 1/445 34/18722 0.558964466529811 0.691549030019362 APOC1 1 GO:0050931 pigment cell differentiation 1/445 34/18722 0.558964466529811 0.691549030019362 CD63 1 GO:0086019 cell-cell signaling involved in cardiac conduction 1/445 34/18722 0.558964466529811 0.691549030019362 PKP2 1 GO:0098751 bone cell development 1/445 34/18722 0.558964466529811 0.691549030019362 TYROBP 1 GO:0008654 phospholipid biosynthetic process 6/445 253/18722 0.559537771225047 0.692051057763673 LPCAT1/IMPA2/ISYNA1/SMG1/PLSCR1/PIK3CA 6 GO:0031570 DNA integrity checkpoint signaling 3/445 123/18722 0.56271197816233 0.695768686557493 SOX4/EIF2AK4/PLK2 3 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling 2/445 79/18722 0.563448580002018 0.696262663472431 HAX1/CBL 2 GO:0060420 regulation of heart growth 2/445 79/18722 0.563448580002018 0.696262663472431 PIM1/BASP1 2 GO:0055088 lipid homeostasis 4/445 167/18722 0.563669709901142 0.696327623086609 APOE/LIMA1/ANGPTL4/PPARG 4 GO:0042180 cellular ketone metabolic process 5/445 211/18722 0.565307787687951 0.697933792868776 APOC1/CD74/ANXA1/HSD17B1/PPARG 5 GO:0046474 glycerophospholipid biosynthetic process 5/445 211/18722 0.565307787687951 0.697933792868776 LPCAT1/IMPA2/SMG1/PLSCR1/PIK3CA 5 GO:0016482 cytosolic transport 4/445 168/18722 0.568398894134488 0.699306138123979 TANC2/SNX2/RDX/LAPTM5 4 GO:0001569 branching involved in blood vessel morphogenesis 1/445 35/18722 0.569466436371112 0.699306138123979 CTNNB1 1 GO:0001893 maternal placenta development 1/445 35/18722 0.569466436371112 0.699306138123979 SPP1 1 GO:0002209 behavioral defense response 1/445 35/18722 0.569466436371112 0.699306138123979 APOE 1 GO:0021955 central nervous system neuron axonogenesis 1/445 35/18722 0.569466436371112 0.699306138123979 HSP90AB1 1 GO:0032205 negative regulation of telomere maintenance 1/445 35/18722 0.569466436371112 0.699306138123979 HNRNPA1 1 GO:0032814 regulation of natural killer cell activation 1/445 35/18722 0.569466436371112 0.699306138123979 TYROBP 1 GO:0033146 regulation of intracellular estrogen receptor signaling pathway 1/445 35/18722 0.569466436371112 0.699306138123979 LBH 1 GO:0035633 maintenance of blood-brain barrier 1/445 35/18722 0.569466436371112 0.699306138123979 TJP1 1 GO:0039694 viral RNA genome replication 1/445 35/18722 0.569466436371112 0.699306138123979 SMARCB1 1 GO:0042462 eye photoreceptor cell development 1/445 35/18722 0.569466436371112 0.699306138123979 THRB 1 GO:0045907 positive regulation of vasoconstriction 1/445 35/18722 0.569466436371112 0.699306138123979 RHOA 1 GO:0045922 negative regulation of fatty acid metabolic process 1/445 35/18722 0.569466436371112 0.699306138123979 APOC1 1 GO:0046471 phosphatidylglycerol metabolic process 1/445 35/18722 0.569466436371112 0.699306138123979 LPCAT1 1 GO:0048821 erythrocyte development 1/445 35/18722 0.569466436371112 0.699306138123979 TMOD3 1 GO:0070536 protein K63-linked deubiquitination 1/445 35/18722 0.569466436371112 0.699306138123979 OTUD1 1 GO:0090181 regulation of cholesterol metabolic process 1/445 35/18722 0.569466436371112 0.699306138123979 APOE 1 GO:1903514 release of sequestered calcium ion into cytosol by endoplasmic reticulum 1/445 35/18722 0.569466436371112 0.699306138123979 SRI 1 GO:0001570 vasculogenesis 2/445 80/18722 0.570299086672999 0.699496890453135 WNT7A/CTNNB1 2 GO:0021766 hippocampus development 2/445 80/18722 0.570299086672999 0.699496890453135 UBA6/UQCRQ 2 GO:0071229 cellular response to acid chemical 2/445 80/18722 0.570299086672999 0.699496890453135 CEBPB/PIK3CA 2 GO:1901264 carbohydrate derivative transport 2/445 80/18722 0.570299086672999 0.699496890453135 SLC25A24/PSAP 2 GO:1903522 regulation of blood circulation 6/445 256/18722 0.571085768244073 0.700253876110498 TPM1/SRI/THRB/PKP2/DSP/RHOA 6 GO:0070585 protein localization to mitochondrion 3/445 125/18722 0.573675218044379 0.703011665897755 HAX1/BNIP3L/DNAJA1 3 GO:1904375 regulation of protein localization to cell periphery 3/445 125/18722 0.573675218044379 0.703011665897755 GOPC/GBP1/VAMP8 3 GO:0008589 regulation of smoothened signaling pathway 2/445 81/18722 0.577071455634616 0.70549931436123 SFRP1/CTNNA1 2 GO:0014032 neural crest cell development 2/445 81/18722 0.577071455634616 0.70549931436123 SEMA4C/PDCD6 2 GO:0021954 central nervous system neuron development 2/445 81/18722 0.577071455634616 0.70549931436123 UQCRQ/HSP90AB1 2 GO:0030641 regulation of cellular pH 2/445 81/18722 0.577071455634616 0.70549931436123 CA2/TMEM165 2 GO:0044773 mitotic DNA damage checkpoint signaling 2/445 81/18722 0.577071455634616 0.70549931436123 SOX4/PLK2 2 GO:0071260 cellular response to mechanical stimulus 2/445 81/18722 0.577071455634616 0.70549931436123 BNIP3/IRF1 2 GO:1903533 regulation of protein targeting 2/445 81/18722 0.577071455634616 0.70549931436123 HAX1/BNIP3L 2 GO:2001021 negative regulation of response to DNA damage stimulus 2/445 81/18722 0.577071455634616 0.70549931436123 CD74/ING2 2 GO:0072330 monocarboxylic acid biosynthetic process 5/445 214/18722 0.577877642443217 0.706275899684299 APOC1/CD74/ANXA1/GSTP1/OSBPL1A 5 GO:0003230 cardiac atrium development 1/445 36/18722 0.579718881162403 0.706436194124451 SOX4 1 GO:0003352 regulation of cilium movement 1/445 36/18722 0.579718881162403 0.706436194124451 CCSAP 1 GO:0006699 bile acid biosynthetic process 1/445 36/18722 0.579718881162403 0.706436194124451 OSBPL1A 1 GO:0007031 peroxisome organization 1/445 36/18722 0.579718881162403 0.706436194124451 RAB8B 1 GO:0010762 regulation of fibroblast migration 1/445 36/18722 0.579718881162403 0.706436194124451 AKAP12 1 GO:0010923 negative regulation of phosphatase activity 1/445 36/18722 0.579718881162403 0.706436194124451 PPP1R15A 1 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway 1/445 36/18722 0.579718881162403 0.706436194124451 CBL 1 GO:0070873 regulation of glycogen metabolic process 1/445 36/18722 0.579718881162403 0.706436194124451 PHLDA2 1 GO:0097009 energy homeostasis 1/445 36/18722 0.579718881162403 0.706436194124451 PIK3CA 1 GO:1901658 glycosyl compound catabolic process 1/445 36/18722 0.579718881162403 0.706436194124451 CDA 1 GO:0048469 cell maturation 4/445 171/18722 0.58241432737403 0.709511526506081 CTNNB1/C1QA/PPARG/GATA3 4 GO:0008543 fibroblast growth factor receptor signaling pathway 2/445 82/18722 0.583765523280828 0.710319698578233 CTNNB1/GATA3 2 GO:0009205 purine ribonucleoside triphosphate metabolic process 2/445 82/18722 0.583765523280828 0.710319698578233 TMSB4X/RHOA 2 GO:0016575 histone deacetylation 2/445 82/18722 0.583765523280828 0.710319698578233 ING2/MORF4L2 2 GO:0046364 monosaccharide biosynthetic process 2/445 82/18722 0.583765523280828 0.710319698578233 FAM3C/ATF4 2 GO:0048565 digestive tract development 3/445 127/18722 0.584466079733179 0.710962713597692 SFRP1/CTNNB1/KLF5 3 GO:0042391 regulation of membrane potential 10/445 434/18722 0.584657999765943 0.710986811019462 WNT7A/SRI/BNIP3/JUN/ZMYND8/BNIP3L/PKP2/EIF4A3/CLDN19/DSP 10 GO:0007219 Notch signaling pathway 4/445 172/18722 0.587027687797451 0.711496844927129 KRT19/EPN2/MAML2/ANXA4 4 GO:0046486 glycerolipid metabolic process 9/445 392/18722 0.589134289913938 0.711496844927129 APOE/APOC1/LPCAT1/IMPA2/SMG1/GDPD3/PLSCR1/PIK3CA/DBI 9 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1/445 37/18722 0.589727716540908 0.711496844927129 RPS19 1 GO:0001990 regulation of systemic arterial blood pressure by hormone 1/445 37/18722 0.589727716540908 0.711496844927129 RHOA 1 GO:0003016 respiratory system process 1/445 37/18722 0.589727716540908 0.711496844927129 YWHAZ 1 GO:0003176 aortic valve development 1/445 37/18722 0.589727716540908 0.711496844927129 GATA3 1 GO:0006623 protein targeting to vacuole 1/445 37/18722 0.589727716540908 0.711496844927129 LAPTM5 1 GO:0006862 nucleotide transport 1/445 37/18722 0.589727716540908 0.711496844927129 SLC25A24 1 GO:0016202 regulation of striated muscle tissue development 1/445 37/18722 0.589727716540908 0.711496844927129 CTNNB1 1 GO:0021532 neural tube patterning 1/445 37/18722 0.589727716540908 0.711496844927129 TMEM107 1 GO:0031112 positive regulation of microtubule polymerization or depolymerization 1/445 37/18722 0.589727716540908 0.711496844927129 HSPA1B 1 GO:0043368 positive T cell selection 1/445 37/18722 0.589727716540908 0.711496844927129 CD74 1 GO:0043687 post-translational protein modification 1/445 37/18722 0.589727716540908 0.711496844927129 ATG12 1 GO:0045616 regulation of keratinocyte differentiation 1/445 37/18722 0.589727716540908 0.711496844927129 GRHL1 1 GO:0045730 respiratory burst 1/445 37/18722 0.589727716540908 0.711496844927129 RPS19 1 GO:0046473 phosphatidic acid metabolic process 1/445 37/18722 0.589727716540908 0.711496844927129 LPCAT1 1 GO:0048009 insulin-like growth factor receptor signaling pathway 1/445 37/18722 0.589727716540908 0.711496844927129 IGFBP3 1 GO:0048846 axon extension involved in axon guidance 1/445 37/18722 0.589727716540908 0.711496844927129 SEMA4C 1 GO:0051294 establishment of spindle orientation 1/445 37/18722 0.589727716540908 0.711496844927129 MAP4 1 GO:0051567 histone H3-K9 methylation 1/445 37/18722 0.589727716540908 0.711496844927129 SMARCB1 1 GO:0060416 response to growth hormone 1/445 37/18722 0.589727716540908 0.711496844927129 CSH1 1 GO:0060428 lung epithelium development 1/445 37/18722 0.589727716540908 0.711496844927129 THRB 1 GO:0071985 multivesicular body sorting pathway 1/445 37/18722 0.589727716540908 0.711496844927129 CHMP5 1 GO:0072529 pyrimidine-containing compound catabolic process 1/445 37/18722 0.589727716540908 0.711496844927129 CDA 1 GO:0090218 positive regulation of lipid kinase activity 1/445 37/18722 0.589727716540908 0.711496844927129 VAV2 1 GO:1902284 neuron projection extension involved in neuron projection guidance 1/445 37/18722 0.589727716540908 0.711496844927129 SEMA4C 1 GO:1902745 positive regulation of lamellipodium organization 1/445 37/18722 0.589727716540908 0.711496844927129 PIK3CA 1 GO:0007389 pattern specification process 10/445 436/18722 0.590500069147064 0.71222066734205 WNT7A/SFRP1/CTNNB1/AIDA/BASP1/LRP2/IRX2/TMEM107/C1QA/ETS2 10 GO:0010469 regulation of signaling receptor activity 4/445 173/18722 0.591611319163861 0.713352702704585 CGA/PHLDA2/CBL/PPARG 4 GO:0007127 meiosis I 3/445 129/18722 0.595081780110608 0.717327935114363 ING2/HSPA2/FOXJ3 3 GO:0006112 energy reserve metabolic process 2/445 84/18722 0.596918356800484 0.718042680462443 PHLDA2/RB1CC1 2 GO:0006835 dicarboxylic acid transport 2/445 84/18722 0.596918356800484 0.718042680462443 LRP2/SLC1A6 2 GO:0010921 regulation of phosphatase activity 2/445 84/18722 0.596918356800484 0.718042680462443 PPP1R15A/HSP90AB1 2 GO:0032508 DNA duplex unwinding 2/445 84/18722 0.596918356800484 0.718042680462443 ANXA1/NAV2 2 GO:0061157 mRNA destabilization 2/445 84/18722 0.596918356800484 0.718042680462443 MEX3D/HNRNPR 2 GO:0098586 cellular response to virus 2/445 84/18722 0.596918356800484 0.718042680462443 RIOK3/LSM14A 2 GO:0034470 ncRNA processing 9/445 395/18722 0.598292573043975 0.718042680462443 MPHOSPH10/ZNHIT6/RIOK3/RPS15/SBDS/RBFA/EIF4A3/RPS19/RPS28 9 GO:0001825 blastocyst formation 1/445 38/18722 0.599498718207448 0.718042680462443 SKIL 1 GO:0002385 mucosal immune response 1/445 38/18722 0.599498718207448 0.718042680462443 RPL39 1 GO:0008210 estrogen metabolic process 1/445 38/18722 0.599498718207448 0.718042680462443 HSD17B1 1 GO:0010742 macrophage derived foam cell differentiation 1/445 38/18722 0.599498718207448 0.718042680462443 PPARG 1 GO:0042596 fear response 1/445 38/18722 0.599498718207448 0.718042680462443 APOE 1 GO:0046676 negative regulation of insulin secretion 1/445 38/18722 0.599498718207448 0.718042680462443 SFRP1 1 GO:0048246 macrophage chemotaxis 1/445 38/18722 0.599498718207448 0.718042680462443 MTUS1 1 GO:0048713 regulation of oligodendrocyte differentiation 1/445 38/18722 0.599498718207448 0.718042680462443 CTNNB1 1 GO:0072538 T-helper 17 type immune response 1/445 38/18722 0.599498718207448 0.718042680462443 NFKBIZ 1 GO:0090077 foam cell differentiation 1/445 38/18722 0.599498718207448 0.718042680462443 PPARG 1 GO:0098926 postsynaptic signal transduction 1/445 38/18722 0.599498718207448 0.718042680462443 GNB1 1 GO:1901031 regulation of response to reactive oxygen species 1/445 38/18722 0.599498718207448 0.718042680462443 PAWR 1 GO:1901186 positive regulation of ERBB signaling pathway 1/445 38/18722 0.599498718207448 0.718042680462443 CBL 1 GO:1903580 positive regulation of ATP metabolic process 1/445 38/18722 0.599498718207448 0.718042680462443 TMSB4X 1 GO:2000279 negative regulation of DNA biosynthetic process 1/445 38/18722 0.599498718207448 0.718042680462443 HNRNPA1 1 GO:0006956 complement activation 3/445 130/18722 0.600323182775509 0.718821758853805 C1QB/C1QA/RGCC 3 GO:0003341 cilium movement 4/445 175/18722 0.600688281579127 0.719050504550384 ING2/CCSAP/TMF1/DNAJA1 4 GO:0042509 regulation of tyrosine phosphorylation of STAT protein 2/445 85/18722 0.603377045064955 0.721641740927426 PARP14/CSH1 2 GO:0044774 mitotic DNA integrity checkpoint signaling 2/445 85/18722 0.603377045064955 0.721641740927426 SOX4/PLK2 2 GO:0072384 organelle transport along microtubule 2/445 85/18722 0.603377045064955 0.721641740927426 AP3S1/ARHGAP21 2 GO:0006661 phosphatidylinositol biosynthetic process 3/445 131/18722 0.605519928010285 0.72399502825195 IMPA2/SMG1/PIK3CA 3 GO:0002701 negative regulation of production of molecular mediator of immune response 1/445 39/18722 0.609037525229374 0.725282836730746 HMOX1 1 GO:0007618 mating 1/445 39/18722 0.609037525229374 0.725282836730746 THRB 1 GO:0010463 mesenchymal cell proliferation 1/445 39/18722 0.609037525229374 0.725282836730746 CTNNB1 1 GO:0017158 regulation of calcium ion-dependent exocytosis 1/445 39/18722 0.609037525229374 0.725282836730746 RAP1B 1 GO:0021587 cerebellum morphogenesis 1/445 39/18722 0.609037525229374 0.725282836730746 WNT7A 1 GO:0031507 heterochromatin assembly 1/445 39/18722 0.609037525229374 0.725282836730746 MBD2 1 GO:0045823 positive regulation of heart contraction 1/445 39/18722 0.609037525229374 0.725282836730746 TPM1 1 GO:0051154 negative regulation of striated muscle cell differentiation 1/445 39/18722 0.609037525229374 0.725282836730746 YBX1 1 GO:0071548 response to dexamethasone 1/445 39/18722 0.609037525229374 0.725282836730746 SERPINF1 1 GO:0090207 regulation of triglyceride metabolic process 1/445 39/18722 0.609037525229374 0.725282836730746 APOE 1 GO:1901021 positive regulation of calcium ion transmembrane transporter activity 1/445 39/18722 0.609037525229374 0.725282836730746 HSPA2 1 GO:1901861 regulation of muscle tissue development 1/445 39/18722 0.609037525229374 0.725282836730746 CTNNB1 1 GO:0030324 lung development 4/445 177/18722 0.609643121503541 0.725282836730746 CTNNB1/YWHAZ/THRB/SPARC 4 GO:0006140 regulation of nucleotide metabolic process 2/445 86/18722 0.609757272322895 0.725282836730746 TMSB4X/CDA 2 GO:0014031 mesenchymal cell development 2/445 86/18722 0.609757272322895 0.725282836730746 SEMA4C/PDCD6 2 GO:0032413 negative regulation of ion transmembrane transporter activity 2/445 86/18722 0.609757272322895 0.725282836730746 SRI/GOPC 2 GO:0035023 regulation of Rho protein signal transduction 2/445 86/18722 0.609757272322895 0.725282836730746 APOE/NET1 2 GO:0046928 regulation of neurotransmitter secretion 2/445 86/18722 0.609757272322895 0.725282836730746 WNT7A/RAP1B 2 GO:0009855 determination of bilateral symmetry 3/445 133/18722 0.615778505356915 0.732146199121758 CTNNB1/AIDA/TMEM107 3 GO:0061014 positive regulation of mRNA catabolic process 2/445 87/18722 0.616059111146751 0.732146199121758 MEX3D/HNRNPR 2 GO:1903578 regulation of ATP metabolic process 2/445 87/18722 0.616059111146751 0.732146199121758 TMSB4X/RHOA 2 GO:1904062 regulation of cation transmembrane transport 8/445 357/18722 0.616691604699052 0.732687092036752 TMSB4X/SRI/HSPA2/SESTD1/WNK1/CD63/CTSS/NDUFA4 8 GO:0014037 Schwann cell differentiation 1/445 40/18722 0.618349643265714 0.732760291546375 NDRG1 1 GO:0044275 cellular carbohydrate catabolic process 1/445 40/18722 0.618349643265714 0.732760291546375 RB1CC1 1 GO:0045022 early endosome to late endosome transport 1/445 40/18722 0.618349643265714 0.732760291546375 RDX 1 GO:0045740 positive regulation of DNA replication 1/445 40/18722 0.618349643265714 0.732760291546375 JUN 1 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol 1/445 40/18722 0.618349643265714 0.732760291546375 SRI 1 GO:0060412 ventricular septum morphogenesis 1/445 40/18722 0.618349643265714 0.732760291546375 SOX4 1 GO:0071526 semaphorin-plexin signaling pathway 1/445 40/18722 0.618349643265714 0.732760291546375 SEMA4C 1 GO:0097352 autophagosome maturation 1/445 40/18722 0.618349643265714 0.732760291546375 VAMP8 1 GO:1901020 negative regulation of calcium ion transmembrane transporter activity 1/445 40/18722 0.618349643265714 0.732760291546375 SRI 1 GO:0009799 specification of symmetry 3/445 134/18722 0.620839921879435 0.735209193490995 CTNNB1/AIDA/TMEM107 3 GO:0046394 carboxylic acid biosynthetic process 7/445 314/18722 0.620950103144537 0.735209193490995 MTHFD1L/APOC1/CD74/ANXA1/GSTP1/OSBPL1A/PLOD2 7 GO:0060249 anatomical structure homeostasis 7/445 314/18722 0.620950103144537 0.735209193490995 LPCAT1/CA2/LYZ/CTNNB1/SPP1/TJP1/WWTR1 7 GO:0007260 tyrosine phosphorylation of STAT protein 2/445 88/18722 0.622282674904542 0.735522097290604 PARP14/CSH1 2 GO:0009144 purine nucleoside triphosphate metabolic process 2/445 88/18722 0.622282674904542 0.735522097290604 TMSB4X/RHOA 2 GO:0030101 natural killer cell activation 2/445 88/18722 0.622282674904542 0.735522097290604 TYROBP/NFIL3 2 GO:0050779 RNA destabilization 2/445 88/18722 0.622282674904542 0.735522097290604 MEX3D/HNRNPR 2 GO:0050829 defense response to Gram-negative bacterium 2/445 88/18722 0.622282674904542 0.735522097290604 LYZ/RPS19 2 GO:1901657 glycosyl compound metabolic process 2/445 88/18722 0.622282674904542 0.735522097290604 AMD1/CDA 2 GO:0061982 meiosis I cell cycle process 3/445 135/18722 0.625855848660628 0.737343121933957 ING2/HSPA2/FOXJ3 3 GO:0006486 protein glycosylation 5/445 226/18722 0.626150402538018 0.737343121933957 GOLGA2/GALNT1/MAN1A1/TMEM165/UBE2J1 5 GO:0043413 macromolecule glycosylation 5/445 226/18722 0.626150402538018 0.737343121933957 GOLGA2/GALNT1/MAN1A1/TMEM165/UBE2J1 5 GO:0030323 respiratory tube development 4/445 181/18722 0.627179096952456 0.737343121933957 CTNNB1/YWHAZ/THRB/SPARC 4 GO:0032640 tumor necrosis factor production 4/445 181/18722 0.627179096952456 0.737343121933957 TYROBP/GSTP1/AKAP12/UBE2J1 4 GO:0032680 regulation of tumor necrosis factor production 4/445 181/18722 0.627179096952456 0.737343121933957 TYROBP/GSTP1/AKAP12/UBE2J1 4 GO:0099504 synaptic vesicle cycle 4/445 181/18722 0.627179096952456 0.737343121933957 WNT7A/CTNNB1/RAP1B/CTBP2 4 GO:0002251 organ or tissue specific immune response 1/445 41/18722 0.627440447716349 0.737343121933957 RPL39 1 GO:0048634 regulation of muscle organ development 1/445 41/18722 0.627440447716349 0.737343121933957 CTNNB1 1 GO:0050691 regulation of defense response to virus by host 1/445 41/18722 0.627440447716349 0.737343121933957 EIF2AK4 1 GO:0050892 intestinal absorption 1/445 41/18722 0.627440447716349 0.737343121933957 LIMA1 1 GO:0055023 positive regulation of cardiac muscle tissue growth 1/445 41/18722 0.627440447716349 0.737343121933957 PIM1 1 GO:0060612 adipose tissue development 1/445 41/18722 0.627440447716349 0.737343121933957 PIK3CA 1 GO:0070296 sarcoplasmic reticulum calcium ion transport 1/445 41/18722 0.627440447716349 0.737343121933957 SRI 1 GO:1900371 regulation of purine nucleotide biosynthetic process 1/445 41/18722 0.627440447716349 0.737343121933957 TMSB4X 1 GO:1901385 regulation of voltage-gated calcium channel activity 1/445 41/18722 0.627440447716349 0.737343121933957 SRI 1 GO:1902622 regulation of neutrophil migration 1/445 41/18722 0.627440447716349 0.737343121933957 CD74 1 GO:1903524 positive regulation of blood circulation 1/445 41/18722 0.627440447716349 0.737343121933957 TPM1 1 GO:1905314 semi-lunar valve development 1/445 41/18722 0.627440447716349 0.737343121933957 GATA3 1 GO:1905521 regulation of macrophage migration 1/445 41/18722 0.627440447716349 0.737343121933957 MTUS1 1 GO:0016053 organic acid biosynthetic process 7/445 316/18722 0.627571633192882 0.737343121933957 MTHFD1L/APOC1/CD74/ANXA1/GSTP1/OSBPL1A/PLOD2 7 GO:0009199 ribonucleoside triphosphate metabolic process 2/445 89/18722 0.628428115788145 0.738139478624063 TMSB4X/RHOA 2 GO:0099024 plasma membrane invagination 3/445 136/18722 0.630826130195843 0.740743319775544 GSN/AIF1/RHOA 3 GO:0010959 regulation of metal ion transport 9/445 406/18722 0.631003568697686 0.740743319775544 NKAIN4/CTNNB1/SRI/HSPA2/SESTD1/PKP2/WNK1/CD63/RHOA 9 GO:0061138 morphogenesis of a branching epithelium 4/445 182/18722 0.631484062128097 0.741096778594083 SFRP1/CTNNB1/SPINT1/GRB2 4 GO:0034644 cellular response to UV 2/445 90/18722 0.634495622911916 0.741291042486896 EIF2AK4/ATF4 2 GO:0048477 oogenesis 2/445 90/18722 0.634495622911916 0.741291042486896 CTNNB1/YTHDC1 2 GO:0000086 G2/M transition of mitotic cell cycle 3/445 137/18722 0.635750630900029 0.741291042486896 HSPA2/KHDRBS1/WEE1 3 GO:0030879 mammary gland development 3/445 137/18722 0.635750630900029 0.741291042486896 CEBPB/LBH/GATA3 3 GO:0055123 digestive system development 3/445 137/18722 0.635750630900029 0.741291042486896 SFRP1/CTNNB1/KLF5 3 GO:0060078 regulation of postsynaptic membrane potential 3/445 137/18722 0.635750630900029 0.741291042486896 WNT7A/ZMYND8/EIF4A3 3 GO:0007212 dopamine receptor signaling pathway 1/445 42/18722 0.636315186797031 0.741291042486896 GNB1 1 GO:0007520 myoblast fusion 1/445 42/18722 0.636315186797031 0.741291042486896 MYOF 1 GO:0009124 nucleoside monophosphate biosynthetic process 1/445 42/18722 0.636315186797031 0.741291042486896 RFK 1 GO:0010591 regulation of lamellipodium assembly 1/445 42/18722 0.636315186797031 0.741291042486896 PIK3CA 1 GO:0010677 negative regulation of cellular carbohydrate metabolic process 1/445 42/18722 0.636315186797031 0.741291042486896 FAM3C 1 GO:0010939 regulation of necrotic cell death 1/445 42/18722 0.636315186797031 0.741291042486896 BNIP3 1 GO:0014003 oligodendrocyte development 1/445 42/18722 0.636315186797031 0.741291042486896 GSTP1 1 GO:0021575 hindbrain morphogenesis 1/445 42/18722 0.636315186797031 0.741291042486896 WNT7A 1 GO:0021879 forebrain neuron differentiation 1/445 42/18722 0.636315186797031 0.741291042486896 UQCRQ 1 GO:0030808 regulation of nucleotide biosynthetic process 1/445 42/18722 0.636315186797031 0.741291042486896 TMSB4X 1 GO:0030890 positive regulation of B cell proliferation 1/445 42/18722 0.636315186797031 0.741291042486896 CD74 1 GO:0032467 positive regulation of cytokinesis 1/445 42/18722 0.636315186797031 0.741291042486896 RHOA 1 GO:0032691 negative regulation of interleukin-1 beta production 1/445 42/18722 0.636315186797031 0.741291042486896 GSTP1 1 GO:0042168 heme metabolic process 1/445 42/18722 0.636315186797031 0.741291042486896 HMOX1 1 GO:0045047 protein targeting to ER 1/445 42/18722 0.636315186797031 0.741291042486896 MAN1A1 1 GO:0045687 positive regulation of glial cell differentiation 1/445 42/18722 0.636315186797031 0.741291042486896 SPINT1 1 GO:0046688 response to copper ion 1/445 42/18722 0.636315186797031 0.741291042486896 MT2A 1 GO:0051452 intracellular pH reduction 1/445 42/18722 0.636315186797031 0.741291042486896 CA2 1 GO:0071312 cellular response to alkaloid 1/445 42/18722 0.636315186797031 0.741291042486896 AIF1 1 GO:2001222 regulation of neuron migration 1/445 42/18722 0.636315186797031 0.741291042486896 SHTN1 1 GO:0071695 anatomical structure maturation 5/445 229/18722 0.637688186554059 0.742681110418612 CTNNB1/C1QA/PPARG/RHOA/GATA3 5 GO:0006885 regulation of pH 2/445 91/18722 0.640485420479398 0.745728656144418 CA2/TMEM165 2 GO:0001504 neurotransmitter uptake 1/445 43/18722 0.644978984541963 0.747589277537275 SLC1A6 1 GO:0006509 membrane protein ectodomain proteolysis 1/445 43/18722 0.644978984541963 0.747589277537275 APOE 1 GO:0010171 body morphogenesis 1/445 43/18722 0.644978984541963 0.747589277537275 ANKRD11 1 GO:0014014 negative regulation of gliogenesis 1/445 43/18722 0.644978984541963 0.747589277537275 CTNNB1 1 GO:0016266 O-glycan processing 1/445 43/18722 0.644978984541963 0.747589277537275 GALNT1 1 GO:0030517 negative regulation of axon extension 1/445 43/18722 0.644978984541963 0.747589277537275 SEMA4C 1 GO:0042181 ketone biosynthetic process 1/445 43/18722 0.644978984541963 0.747589277537275 HSD17B1 1 GO:0045840 positive regulation of mitotic nuclear division 1/445 43/18722 0.644978984541963 0.747589277537275 RGCC 1 GO:0045981 positive regulation of nucleotide metabolic process 1/445 43/18722 0.644978984541963 0.747589277537275 TMSB4X 1 GO:0046636 negative regulation of alpha-beta T cell activation 1/445 43/18722 0.644978984541963 0.747589277537275 ANXA1 1 GO:0090278 negative regulation of peptide hormone secretion 1/445 43/18722 0.644978984541963 0.747589277537275 SFRP1 1 GO:0098927 vesicle-mediated transport between endosomal compartments 1/445 43/18722 0.644978984541963 0.747589277537275 RDX 1 GO:0120178 steroid hormone biosynthetic process 1/445 43/18722 0.644978984541963 0.747589277537275 HSD17B1 1 GO:1900544 positive regulation of purine nucleotide metabolic process 1/445 43/18722 0.644978984541963 0.747589277537275 TMSB4X 1 GO:1901381 positive regulation of potassium ion transmembrane transport 1/445 43/18722 0.644978984541963 0.747589277537275 WNK1 1 GO:1903793 positive regulation of anion transport 1/445 43/18722 0.644978984541963 0.747589277537275 CEBPB 1 GO:0001708 cell fate specification 2/445 92/18722 0.646397766016002 0.748393826068415 CTNNB1/LMO4 2 GO:0006497 protein lipidation 2/445 92/18722 0.646397766016002 0.748393826068415 ATG12/DBI 2 GO:0034502 protein localization to chromosome 2/445 92/18722 0.646397766016002 0.748393826068415 GNL3/CCT6A 2 GO:1903351 cellular response to dopamine 2/445 92/18722 0.646397766016002 0.748393826068415 GNB1/ATF4 2 GO:0071706 tumor necrosis factor superfamily cytokine production 4/445 186/18722 0.648382757219223 0.750271476210815 TYROBP/GSTP1/AKAP12/UBE2J1 4 GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 4/445 186/18722 0.648382757219223 0.750271476210815 TYROBP/GSTP1/AKAP12/UBE2J1 4 GO:0007589 body fluid secretion 2/445 93/18722 0.652232948665532 0.751907409880768 WNK1/VAMP8 2 GO:0060349 bone morphogenesis 2/445 93/18722 0.652232948665532 0.751907409880768 OSR2/TMEM107 2 GO:1901019 regulation of calcium ion transmembrane transporter activity 2/445 93/18722 0.652232948665532 0.751907409880768 SRI/HSPA2 2 GO:1903350 response to dopamine 2/445 93/18722 0.652232948665532 0.751907409880768 GNB1/ATF4 2 GO:0002066 columnar/cuboidal epithelial cell development 1/445 44/18722 0.653436843735647 0.751907409880768 KLF5 1 GO:0006378 mRNA polyadenylation 1/445 44/18722 0.653436843735647 0.751907409880768 YTHDC1 1 GO:0006775 fat-soluble vitamin metabolic process 1/445 44/18722 0.653436843735647 0.751907409880768 LRP2 1 GO:0007528 neuromuscular junction development 1/445 44/18722 0.653436843735647 0.751907409880768 PPFIBP1 1 GO:0031295 T cell costimulation 1/445 44/18722 0.653436843735647 0.751907409880768 PIK3CA 1 GO:0032007 negative regulation of TOR signaling 1/445 44/18722 0.653436843735647 0.751907409880768 PDCD6 1 GO:0032620 interleukin-17 production 1/445 44/18722 0.653436843735647 0.751907409880768 SLC7A5 1 GO:0032660 regulation of interleukin-17 production 1/445 44/18722 0.653436843735647 0.751907409880768 SLC7A5 1 GO:0032881 regulation of polysaccharide metabolic process 1/445 44/18722 0.653436843735647 0.751907409880768 PHLDA2 1 GO:0044058 regulation of digestive system process 1/445 44/18722 0.653436843735647 0.751907409880768 WNK1 1 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity 1/445 44/18722 0.653436843735647 0.751907409880768 RHOA 1 GO:0048066 developmental pigmentation 1/445 44/18722 0.653436843735647 0.751907409880768 CD63 1 GO:0050999 regulation of nitric-oxide synthase activity 1/445 44/18722 0.653436843735647 0.751907409880768 APOE 1 GO:0060324 face development 1/445 44/18722 0.653436843735647 0.751907409880768 ANKRD11 1 GO:0062208 positive regulation of pattern recognition receptor signaling pathway 1/445 44/18722 0.653436843735647 0.751907409880768 HSPA1B 1 GO:1903573 negative regulation of response to endoplasmic reticulum stress 1/445 44/18722 0.653436843735647 0.751907409880768 PPP1R15A 1 GO:0006470 protein dephosphorylation 6/445 281/18722 0.661016575645077 0.758871866488704 ANKLE2/PPP1R15A/PPP2R2D/HSP90AB1/PPM1G/CAMTA1 6 GO:0003009 skeletal muscle contraction 1/445 45/18722 0.661693648775674 0.758871866488704 TNNI2 1 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress 1/445 45/18722 0.661693648775674 0.758871866488704 MCL1 1 GO:0032309 icosanoid secretion 1/445 45/18722 0.661693648775674 0.758871866488704 ANXA1 1 GO:0035305 negative regulation of dephosphorylation 1/445 45/18722 0.661693648775674 0.758871866488704 PPP1R15A 1 GO:0042551 neuron maturation 1/445 45/18722 0.661693648775674 0.758871866488704 C1QA 1 GO:0043631 RNA polyadenylation 1/445 45/18722 0.661693648775674 0.758871866488704 YTHDC1 1 GO:0045933 positive regulation of muscle contraction 1/445 45/18722 0.661693648775674 0.758871866488704 RHOA 1 GO:0046189 phenol-containing compound biosynthetic process 1/445 45/18722 0.661693648775674 0.758871866488704 GATA3 1 GO:0048599 oocyte development 1/445 45/18722 0.661693648775674 0.758871866488704 CTNNB1 1 GO:0071354 cellular response to interleukin-6 1/445 45/18722 0.661693648775674 0.758871866488704 JAK1 1 GO:0085029 extracellular matrix assembly 1/445 45/18722 0.661693648775674 0.758871866488704 RGCC 1 GO:0016311 dephosphorylation 9/445 417/18722 0.662242340316416 0.759290343560121 IMPA2/ANKLE2/PPP1R15A/PPP2R2D/HSP90AB1/PLPP3/DUSP4/PPM1G/CAMTA1 9 GO:0002532 production of molecular mediator involved in inflammatory response 2/445 95/18722 0.66367313018069 0.759665752501089 RPS19/VAMP8 2 GO:0032479 regulation of type I interferon production 2/445 95/18722 0.66367313018069 0.759665752501089 RIOK3/IRF1 2 GO:0032606 type I interferon production 2/445 95/18722 0.66367313018069 0.759665752501089 RIOK3/IRF1 2 GO:0042982 amyloid precursor protein metabolic process 2/445 95/18722 0.66367313018069 0.759665752501089 APOE/PAWR 2 GO:0045666 positive regulation of neuron differentiation 2/445 95/18722 0.66367313018069 0.759665752501089 CPNE1/RHOA 2 GO:1901379 regulation of potassium ion transmembrane transport 2/445 95/18722 0.66367313018069 0.759665752501089 WNK1/CD63 2 GO:0006865 amino acid transport 3/445 143/18722 0.66433101946188 0.759997629852403 SLC7A1/SLC1A6/SLC7A5 3 GO:0034763 negative regulation of transmembrane transport 3/445 143/18722 0.66433101946188 0.759997629852403 SRI/GOPC/SESTD1 3 GO:0051216 cartilage development 4/445 190/18722 0.664761269390015 0.760279292317317 OSR2/WNT7A/CTNNB1/EFEMP1 4 GO:0010324 membrane invagination 3/445 144/18722 0.668932819007602 0.761981401801594 GSN/AIF1/RHOA 3 GO:0031644 regulation of nervous system process 3/445 144/18722 0.668932819007602 0.761981401801594 WNT7A/ZMYND8/EIF4A3 3 GO:0106106 cold-induced thermogenesis 3/445 144/18722 0.668932819007602 0.761981401801594 CEBPB/PLCL2/ATF4 3 GO:0120161 regulation of cold-induced thermogenesis 3/445 144/18722 0.668932819007602 0.761981401801594 CEBPB/PLCL2/ATF4 3 GO:0042632 cholesterol homeostasis 2/445 96/18722 0.669278850948727 0.761981401801594 APOE/LIMA1 2 GO:0044264 cellular polysaccharide metabolic process 2/445 96/18722 0.669278850948727 0.761981401801594 PHLDA2/RB1CC1 2 GO:0001974 blood vessel remodeling 1/445 46/18722 0.669754168468067 0.761981401801594 CST3 1 GO:0006383 transcription by RNA polymerase III 1/445 46/18722 0.669754168468067 0.761981401801594 POLR2L 1 GO:0031294 lymphocyte costimulation 1/445 46/18722 0.669754168468067 0.761981401801594 PIK3CA 1 GO:0031648 protein destabilization 1/445 46/18722 0.669754168468067 0.761981401801594 GSN 1 GO:0035094 response to nicotine 1/445 46/18722 0.669754168468067 0.761981401801594 HMOX1 1 GO:0043462 regulation of ATPase activity 1/445 46/18722 0.669754168468067 0.761981401801594 TPM1 1 GO:0045851 pH reduction 1/445 46/18722 0.669754168468067 0.761981401801594 CA2 1 GO:0046839 phospholipid dephosphorylation 1/445 46/18722 0.669754168468067 0.761981401801594 PLPP3 1 GO:0060976 coronary vasculature development 1/445 46/18722 0.669754168468067 0.761981401801594 LRP2 1 GO:0061462 protein localization to lysosome 1/445 46/18722 0.669754168468067 0.761981401801594 LAPTM5 1 GO:0070828 heterochromatin organization 1/445 46/18722 0.669754168468067 0.761981401801594 MBD2 1 GO:0072599 establishment of protein localization to endoplasmic reticulum 1/445 46/18722 0.669754168468067 0.761981401801594 MAN1A1 1 GO:2000107 negative regulation of leukocyte apoptotic process 1/445 46/18722 0.669754168468067 0.761981401801594 CD74 1 GO:0007269 neurotransmitter secretion 3/445 145/18722 0.673488406513351 0.765808039445817 WNT7A/RAP1B/CTBP2 3 GO:0099643 signal release from synapse 3/445 145/18722 0.673488406513351 0.765808039445817 WNT7A/RAP1B/CTBP2 3 GO:0055092 sterol homeostasis 2/445 97/18722 0.674808849643037 0.765871643152994 APOE/LIMA1 2 GO:1990868 response to chemokine 2/445 97/18722 0.674808849643037 0.765871643152994 WNK1/RHOA 2 GO:1990869 cellular response to chemokine 2/445 97/18722 0.674808849643037 0.765871643152994 WNK1/RHOA 2 GO:0001754 eye photoreceptor cell differentiation 1/445 47/18722 0.677623058756765 0.765871643152994 THRB 1 GO:0010761 fibroblast migration 1/445 47/18722 0.677623058756765 0.765871643152994 AKAP12 1 GO:0016574 histone ubiquitination 1/445 47/18722 0.677623058756765 0.765871643152994 RYBP 1 GO:0031641 regulation of myelination 1/445 47/18722 0.677623058756765 0.765871643152994 CTNNB1 1 GO:0032369 negative regulation of lipid transport 1/445 47/18722 0.677623058756765 0.765871643152994 APOC1 1 GO:0035315 hair cell differentiation 1/445 47/18722 0.677623058756765 0.765871643152994 CTNNB1 1 GO:0042311 vasodilation 1/445 47/18722 0.677623058756765 0.765871643152994 APOE 1 GO:0045332 phospholipid translocation 1/445 47/18722 0.677623058756765 0.765871643152994 PLSCR1 1 GO:0045646 regulation of erythrocyte differentiation 1/445 47/18722 0.677623058756765 0.765871643152994 HSPA1B 1 GO:0045747 positive regulation of Notch signaling pathway 1/445 47/18722 0.677623058756765 0.765871643152994 EPN2 1 GO:0047496 vesicle transport along microtubule 1/445 47/18722 0.677623058756765 0.765871643152994 AP3S1 1 GO:0051489 regulation of filopodium assembly 1/445 47/18722 0.677623058756765 0.765871643152994 ZMYND8 1 GO:0061001 regulation of dendritic spine morphogenesis 1/445 47/18722 0.677623058756765 0.765871643152994 TANC2 1 GO:0072583 clathrin-dependent endocytosis 1/445 47/18722 0.677623058756765 0.765871643152994 CLTB 1 GO:0090279 regulation of calcium ion import 1/445 47/18722 0.677623058756765 0.765871643152994 CTNNB1 1 GO:0101023 vascular endothelial cell proliferation 1/445 47/18722 0.677623058756765 0.765871643152994 PPARG 1 GO:1900744 regulation of p38MAPK cascade 1/445 47/18722 0.677623058756765 0.765871643152994 SASH1 1 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis 1/445 47/18722 0.677623058756765 0.765871643152994 HMOX1 1 GO:1905562 regulation of vascular endothelial cell proliferation 1/445 47/18722 0.677623058756765 0.765871643152994 PPARG 1 GO:0070085 glycosylation 5/445 240/18722 0.678074275917271 0.766172000496238 GOLGA2/GALNT1/MAN1A1/TMEM165/UBE2J1 5 GO:0043502 regulation of muscle adaptation 2/445 98/18722 0.680263550044164 0.768435527818552 KLF4/AIF1 2 GO:0030900 forebrain development 8/445 379/18722 0.682309055594206 0.770535458900947 WNT7A/CTNNB1/TYROBP/BNIP3/UBA6/LRP2/UQCRQ/RHOA 8 GO:0002673 regulation of acute inflammatory response 1/445 48/18722 0.685304865388799 0.770928927452311 GSTP1 1 GO:0002686 negative regulation of leukocyte migration 1/445 48/18722 0.685304865388799 0.770928927452311 HMOX1 1 GO:0006111 regulation of gluconeogenesis 1/445 48/18722 0.685304865388799 0.770928927452311 FAM3C 1 GO:0015804 neutral amino acid transport 1/445 48/18722 0.685304865388799 0.770928927452311 SLC7A5 1 GO:0030261 chromosome condensation 1/445 48/18722 0.685304865388799 0.770928927452311 DFFB 1 GO:0032527 protein exit from endoplasmic reticulum 1/445 48/18722 0.685304865388799 0.770928927452311 UBE2J1 1 GO:0033628 regulation of cell adhesion mediated by integrin 1/445 48/18722 0.685304865388799 0.770928927452311 WNK1 1 GO:0042908 xenobiotic transport 1/445 48/18722 0.685304865388799 0.770928927452311 SLC7A5 1 GO:0045912 negative regulation of carbohydrate metabolic process 1/445 48/18722 0.685304865388799 0.770928927452311 FAM3C 1 GO:0048146 positive regulation of fibroblast proliferation 1/445 48/18722 0.685304865388799 0.770928927452311 CD74 1 GO:0090199 regulation of release of cytochrome c from mitochondria 1/445 48/18722 0.685304865388799 0.770928927452311 BNIP3 1 GO:0120009 intermembrane lipid transfer 1/445 48/18722 0.685304865388799 0.770928927452311 APOE 1 GO:1902003 regulation of amyloid-beta formation 1/445 48/18722 0.685304865388799 0.770928927452311 APOE 1 GO:0007631 feeding behavior 2/445 99/18722 0.685643398562041 0.770928927452311 FOS/EIF2AK4 2 GO:0021510 spinal cord development 2/445 99/18722 0.685643398562041 0.770928927452311 SOX4/LMO4 2 GO:0051153 regulation of striated muscle cell differentiation 2/445 99/18722 0.685643398562041 0.770928927452311 YBX1/MORF4L2 2 GO:0044839 cell cycle G2/M phase transition 3/445 148/18722 0.686878171782489 0.77210713677101 HSPA2/KHDRBS1/WEE1 3 GO:0001763 morphogenesis of a branching structure 4/445 196/18722 0.688340783014248 0.773297334109806 SFRP1/CTNNB1/SPINT1/GRB2 4 GO:0006006 glucose metabolic process 4/445 196/18722 0.688340783014248 0.773297334109806 PHLDA2/PIK3CA/FAM3C/ATF4 4 GO:0007018 microtubule-based movement 8/445 382/18722 0.690696411808919 0.773297334109806 AP3S1/ING2/CCSAP/ARHGAP21/KIF2A/TMF1/MAP4/DNAJA1 8 GO:0006626 protein targeting to mitochondrion 2/445 100/18722 0.690948862926079 0.773297334109806 HAX1/BNIP3L 2 GO:0006641 triglyceride metabolic process 2/445 100/18722 0.690948862926079 0.773297334109806 APOE/APOC1 2 GO:0051588 regulation of neurotransmitter transport 2/445 100/18722 0.690948862926079 0.773297334109806 WNT7A/RAP1B 2 GO:0009411 response to UV 3/445 149/18722 0.691249258372914 0.773297334109806 HMGN1/EIF2AK4/ATF4 3 GO:0006778 porphyrin-containing compound metabolic process 1/445 49/18722 0.692804026516676 0.773297334109806 HMOX1 1 GO:0008038 neuron recognition 1/445 49/18722 0.692804026516676 0.773297334109806 YWHAZ 1 GO:0008206 bile acid metabolic process 1/445 49/18722 0.692804026516676 0.773297334109806 OSBPL1A 1 GO:0009994 oocyte differentiation 1/445 49/18722 0.692804026516676 0.773297334109806 CTNNB1 1 GO:0030195 negative regulation of blood coagulation 1/445 49/18722 0.692804026516676 0.773297334109806 APOE 1 GO:0030857 negative regulation of epithelial cell differentiation 1/445 49/18722 0.692804026516676 0.773297334109806 CTNNB1 1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 1/445 49/18722 0.692804026516676 0.773297334109806 WWTR1 1 GO:0032692 negative regulation of interleukin-1 production 1/445 49/18722 0.692804026516676 0.773297334109806 GSTP1 1 GO:0035088 establishment or maintenance of apical/basal cell polarity 1/445 49/18722 0.692804026516676 0.773297334109806 RHOA 1 GO:0042461 photoreceptor cell development 1/445 49/18722 0.692804026516676 0.773297334109806 THRB 1 GO:0046580 negative regulation of Ras protein signal transduction 1/445 49/18722 0.692804026516676 0.773297334109806 MAPKAP1 1 GO:0048168 regulation of neuronal synaptic plasticity 1/445 49/18722 0.692804026516676 0.773297334109806 APOE 1 GO:0051445 regulation of meiotic cell cycle 1/445 49/18722 0.692804026516676 0.773297334109806 CALR 1 GO:0051932 synaptic transmission, GABAergic 1/445 49/18722 0.692804026516676 0.773297334109806 PLCL2 1 GO:0060964 regulation of gene silencing by miRNA 1/445 49/18722 0.692804026516676 0.773297334109806 PPARG 1 GO:0061245 establishment or maintenance of bipolar cell polarity 1/445 49/18722 0.692804026516676 0.773297334109806 RHOA 1 GO:0070741 response to interleukin-6 1/445 49/18722 0.692804026516676 0.773297334109806 JAK1 1 GO:0072666 establishment of protein localization to vacuole 1/445 49/18722 0.692804026516676 0.773297334109806 LAPTM5 1 GO:1990573 potassium ion import across plasma membrane 1/445 49/18722 0.692804026516676 0.773297334109806 WNK1 1 GO:0051963 regulation of synapse assembly 2/445 101/18722 0.696180430924496 0.77685612105594 WNT7A/UBE2V2 2 GO:0007080 mitotic metaphase plate congression 1/445 50/18722 0.700124875239435 0.778943134827392 CHMP5 1 GO:0008089 anterograde axonal transport 1/445 50/18722 0.700124875239435 0.778943134827392 AP3S1 1 GO:0010665 regulation of cardiac muscle cell apoptotic process 1/445 50/18722 0.700124875239435 0.778943134827392 BNIP3 1 GO:0038202 TORC1 signaling 1/445 50/18722 0.700124875239435 0.778943134827392 SMG1 1 GO:0043268 positive regulation of potassium ion transport 1/445 50/18722 0.700124875239435 0.778943134827392 WNK1 1 GO:0045814 negative regulation of gene expression, epigenetic 1/445 50/18722 0.700124875239435 0.778943134827392 MBD2 1 GO:0060425 lung morphogenesis 1/445 50/18722 0.700124875239435 0.778943134827392 CTNNB1 1 GO:0090102 cochlea development 1/445 50/18722 0.700124875239435 0.778943134827392 GATA3 1 GO:0099054 presynapse assembly 1/445 50/18722 0.700124875239435 0.778943134827392 WNT7A 1 GO:1900047 negative regulation of hemostasis 1/445 50/18722 0.700124875239435 0.778943134827392 APOE 1 GO:1902930 regulation of alcohol biosynthetic process 1/445 50/18722 0.700124875239435 0.778943134827392 APOE 1 GO:1904063 negative regulation of cation transmembrane transport 2/445 102/18722 0.70133860919129 0.780083412646531 SRI/SESTD1 2 GO:0051604 protein maturation 6/445 294/18722 0.702837454562263 0.781540114346355 ERO1A/GSN/SOX4/SRGN/CALR/CTSS 6 GO:0099003 vesicle-mediated transport in synapse 4/445 200/18722 0.703397096206819 0.781951938759518 WNT7A/CTNNB1/RAP1B/CTBP2 4 GO:0021537 telencephalon development 5/445 248/18722 0.705498879287947 0.783518142517641 CTNNB1/BNIP3/UBA6/UQCRQ/RHOA 5 GO:0030004 cellular monovalent inorganic cation homeostasis 2/445 103/18722 0.70642392203932 0.783518142517641 CA2/TMEM165 2 GO:0032760 positive regulation of tumor necrosis factor production 2/445 103/18722 0.70642392203932 0.783518142517641 TYROBP/AKAP12 2 GO:0009952 anterior/posterior pattern specification 4/445 201/18722 0.707078117091627 0.783518142517641 SFRP1/CTNNB1/BASP1/ETS2 4 GO:0010656 negative regulation of muscle cell apoptotic process 1/445 51/18722 0.707271642083825 0.783518142517641 HMOX1 1 GO:0014009 glial cell proliferation 1/445 51/18722 0.707271642083825 0.783518142517641 SOX4 1 GO:0045661 regulation of myoblast differentiation 1/445 51/18722 0.707271642083825 0.783518142517641 IGFBP3 1 GO:0050982 detection of mechanical stimulus 1/445 51/18722 0.707271642083825 0.783518142517641 CTNNB1 1 GO:0051293 establishment of spindle localization 1/445 51/18722 0.707271642083825 0.783518142517641 MAP4 1 GO:0060043 regulation of cardiac muscle cell proliferation 1/445 51/18722 0.707271642083825 0.783518142517641 PIM1 1 GO:0060632 regulation of microtubule-based movement 1/445 51/18722 0.707271642083825 0.783518142517641 CCSAP 1 GO:0071622 regulation of granulocyte chemotaxis 1/445 51/18722 0.707271642083825 0.783518142517641 CD74 1 GO:1903307 positive regulation of regulated secretory pathway 1/445 51/18722 0.707271642083825 0.783518142517641 VAMP8 1 GO:0016051 carbohydrate biosynthetic process 4/445 202/18722 0.710725934932326 0.787133736516203 IMPA2/ISYNA1/FAM3C/ATF4 4 GO:0022600 digestive system process 2/445 104/18722 0.711436910337988 0.787498895124927 LIMA1/WNK1 2 GO:0060419 heart growth 2/445 104/18722 0.711436910337988 0.787498895124927 PIM1/BASP1 2 GO:0007605 sensory perception of sound 3/445 154/18722 0.712417153757491 0.788372692786551 THRB/LRP2/NAV2 3 GO:0010662 regulation of striated muscle cell apoptotic process 1/445 52/18722 0.714248457427015 0.789553218525823 BNIP3 1 GO:0034204 lipid translocation 1/445 52/18722 0.714248457427015 0.789553218525823 PLSCR1 1 GO:0045010 actin nucleation 1/445 52/18722 0.714248457427015 0.789553218525823 GSN 1 GO:0060147 regulation of posttranscriptional gene silencing 1/445 52/18722 0.714248457427015 0.789553218525823 PPARG 1 GO:2001022 positive regulation of response to DNA damage stimulus 2/445 105/18722 0.716378130434076 0.791633974593258 SKIL/UBE2V2 2 GO:0046434 organophosphate catabolic process 3/445 155/18722 0.716514023482012 0.791633974593258 APOC1/IMPA2/GDPD3 3 GO:0045017 glycerolipid biosynthetic process 5/445 252/18722 0.718586479642556 0.793499264208339 LPCAT1/IMPA2/SMG1/PLSCR1/PIK3CA 5 GO:0061448 connective tissue development 5/445 252/18722 0.718586479642556 0.793499264208339 OSR2/WNT7A/CTNNB1/EFEMP1/PIK3CA 5 GO:0001764 neuron migration 3/445 156/18722 0.720565643417137 0.794526965470734 CTNNB1/SHTN1/GATA3 3 GO:0008347 glial cell migration 1/445 53/18722 0.721059353862204 0.794526965470734 CTNNB1 1 GO:0033059 cellular pigmentation 1/445 53/18722 0.721059353862204 0.794526965470734 CD63 1 GO:0045806 negative regulation of endocytosis 1/445 53/18722 0.721059353862204 0.794526965470734 APOC1 1 GO:0050819 negative regulation of coagulation 1/445 53/18722 0.721059353862204 0.794526965470734 APOE 1 GO:0060966 regulation of gene silencing by RNA 1/445 53/18722 0.721059353862204 0.794526965470734 PPARG 1 GO:0071715 icosanoid transport 1/445 53/18722 0.721059353862204 0.794526965470734 ANXA1 1 GO:0099172 presynapse organization 1/445 53/18722 0.721059353862204 0.794526965470734 WNT7A 1 GO:0007218 neuropeptide signaling pathway 2/445 106/18722 0.721248153114319 0.794526965470734 KISS1R/TAC3 2 GO:0072503 cellular divalent inorganic cation homeostasis 10/445 486/18722 0.722488954821734 0.79568165085806 APOE/S100A9/SRI/ERO1A/BNIP3/S100A8/MT2A/GNB1/TMEM165/CALR 10 GO:1990845 adaptive thermogenesis 3/445 157/18722 0.724572172358414 0.797763231346643 CEBPB/PLCL2/ATF4 3 GO:0006839 mitochondrial transport 5/445 254/18722 0.724973625150088 0.797813921764472 SLC25A24/HAX1/SLC25A37/BNIP3/BNIP3L 5 GO:0005976 polysaccharide metabolic process 2/445 107/18722 0.726047562608362 0.797813921764472 PHLDA2/RB1CC1 2 GO:0006275 regulation of DNA replication 2/445 107/18722 0.726047562608362 0.797813921764472 TSPYL2/JUN 2 GO:0021761 limbic system development 2/445 107/18722 0.726047562608362 0.797813921764472 UBA6/UQCRQ 2 GO:0071868 cellular response to monoamine stimulus 2/445 107/18722 0.726047562608362 0.797813921764472 GNB1/ATF4 2 GO:0071870 cellular response to catecholamine stimulus 2/445 107/18722 0.726047562608362 0.797813921764472 GNB1/ATF4 2 GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 2/445 107/18722 0.726047562608362 0.797813921764472 TYROBP/AKAP12 2 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis 1/445 54/18722 0.72770826850848 0.797813921764472 HMOX1 1 GO:0006584 catecholamine metabolic process 1/445 54/18722 0.72770826850848 0.797813921764472 GATA3 1 GO:0009712 catechol-containing compound metabolic process 1/445 54/18722 0.72770826850848 0.797813921764472 GATA3 1 GO:0010524 positive regulation of calcium ion transport into cytosol 1/445 54/18722 0.72770826850848 0.797813921764472 SRI 1 GO:0014888 striated muscle adaptation 1/445 54/18722 0.72770826850848 0.797813921764472 GSN 1 GO:0043647 inositol phosphate metabolic process 1/445 54/18722 0.72770826850848 0.797813921764472 IMPA2 1 GO:0070839 metal ion export 1/445 54/18722 0.72770826850848 0.797813921764472 SLC40A1 1 GO:0072348 sulfur compound transport 1/445 54/18722 0.72770826850848 0.797813921764472 SLC13A4 1 GO:1902743 regulation of lamellipodium organization 1/445 54/18722 0.72770826850848 0.797813921764472 PIK3CA 1 GO:0051924 regulation of calcium ion transport 5/445 255/18722 0.728128043519829 0.798062336901144 CTNNB1/SRI/HSPA2/SESTD1/RHOA 5 GO:0006958 complement activation, classical pathway 2/445 108/18722 0.730776955630754 0.800753210533327 C1QB/C1QA 2 GO:0006836 neurotransmitter transport 4/445 208/18722 0.73191741406641 0.801790198225495 WNT7A/RAP1B/CTBP2/SLC1A6 4 GO:0046488 phosphatidylinositol metabolic process 3/445 159/18722 0.732450642661106 0.801949007376896 IMPA2/SMG1/PIK3CA 3 GO:1903169 regulation of calcium ion transmembrane transport 3/445 159/18722 0.732450642661106 0.801949007376896 SRI/HSPA2/SESTD1 3 GO:0001755 neural crest cell migration 1/445 55/18722 0.734199045266232 0.802124680753708 SEMA4C 1 GO:0031113 regulation of microtubule polymerization 1/445 55/18722 0.734199045266232 0.802124680753708 HSPA1B 1 GO:0038066 p38MAPK cascade 1/445 55/18722 0.734199045266232 0.802124680753708 SASH1 1 GO:0042220 response to cocaine 1/445 55/18722 0.734199045266232 0.802124680753708 HSP90AB1 1 GO:0043331 response to dsRNA 1/445 55/18722 0.734199045266232 0.802124680753708 RIOK3 1 GO:0061098 positive regulation of protein tyrosine kinase activity 1/445 55/18722 0.734199045266232 0.802124680753708 PAK2 1 GO:1902991 regulation of amyloid precursor protein catabolic process 1/445 55/18722 0.734199045266232 0.802124680753708 APOE 1 GO:1905517 macrophage migration 1/445 55/18722 0.734199045266232 0.802124680753708 MTUS1 1 GO:0005996 monosaccharide metabolic process 5/445 257/18722 0.734358640186523 0.802124680753708 PHLDA2/SLC2A3/PIK3CA/FAM3C/ATF4 5 GO:0032410 negative regulation of transporter activity 2/445 109/18722 0.735436940460717 0.802877907252437 SRI/GOPC 2 GO:0043266 regulation of potassium ion transport 2/445 109/18722 0.735436940460717 0.802877907252437 WNK1/CD63 2 GO:0090316 positive regulation of intracellular protein transport 3/445 160/18722 0.736322950700927 0.803632789787458 NUTF2/HSP90AB1/TCF7L2 3 GO:0018958 phenol-containing compound metabolic process 2/445 110/18722 0.740028136058421 0.806738367702314 CGA/GATA3 2 GO:0001658 branching involved in ureteric bud morphogenesis 1/445 56/18722 0.740535437019408 0.806738367702314 CTNNB1 1 GO:0002090 regulation of receptor internalization 1/445 56/18722 0.740535437019408 0.806738367702314 CD63 1 GO:0015800 acidic amino acid transport 1/445 56/18722 0.740535437019408 0.806738367702314 SLC1A6 1 GO:0048255 mRNA stabilization 1/445 56/18722 0.740535437019408 0.806738367702314 YBX1 1 GO:0051058 negative regulation of small GTPase mediated signal transduction 1/445 56/18722 0.740535437019408 0.806738367702314 MAPKAP1 1 GO:0051653 spindle localization 1/445 56/18722 0.740535437019408 0.806738367702314 MAP4 1 GO:0030100 regulation of endocytosis 4/445 211/18722 0.742068440225637 0.80819528778595 APOE/APOC1/CBL/CD63 4 GO:0090150 establishment of protein localization to membrane 5/445 260/18722 0.743509281718979 0.809209049387024 GOPC/GOLGA4/MACF1/RAB8B/GOLPH3 5 GO:0001938 positive regulation of endothelial cell proliferation 2/445 111/18722 0.744551171216568 0.809209049387024 HMOX1/PDCD6 2 GO:0015718 monocarboxylic acid transport 2/445 111/18722 0.744551171216568 0.809209049387024 SLC16A3/ANXA1 2 GO:0071867 response to monoamine 2/445 111/18722 0.744551171216568 0.809209049387024 GNB1/ATF4 2 GO:0071869 response to catecholamine 2/445 111/18722 0.744551171216568 0.809209049387024 GNB1/ATF4 2 GO:0051321 meiotic cell cycle 5/445 261/18722 0.746507551999089 0.809209049387024 ING2/HSPA2/GOLGA2/FOXJ3/CALR 5 GO:0006695 cholesterol biosynthetic process 1/445 57/18722 0.746721107785848 0.809209049387024 APOE 1 GO:0006754 ATP biosynthetic process 1/445 57/18722 0.746721107785848 0.809209049387024 TMSB4X 1 GO:0033619 membrane protein proteolysis 1/445 57/18722 0.746721107785848 0.809209049387024 APOE 1 GO:0034205 amyloid-beta formation 1/445 57/18722 0.746721107785848 0.809209049387024 APOE 1 GO:0050879 multicellular organismal movement 1/445 57/18722 0.746721107785848 0.809209049387024 TNNI2 1 GO:0050881 musculoskeletal movement 1/445 57/18722 0.746721107785848 0.809209049387024 TNNI2 1 GO:0050891 multicellular organismal water homeostasis 1/445 57/18722 0.746721107785848 0.809209049387024 GRHL1 1 GO:0051155 positive regulation of striated muscle cell differentiation 1/445 57/18722 0.746721107785848 0.809209049387024 MORF4L2 1 GO:0051289 protein homotetramerization 1/445 57/18722 0.746721107785848 0.809209049387024 GOLGA2 1 GO:0051785 positive regulation of nuclear division 1/445 57/18722 0.746721107785848 0.809209049387024 RGCC 1 GO:0060042 retina morphogenesis in camera-type eye 1/445 57/18722 0.746721107785848 0.809209049387024 THRB 1 GO:0097120 receptor localization to synapse 1/445 57/18722 0.746721107785848 0.809209049387024 TYROBP 1 GO:1902653 secondary alcohol biosynthetic process 1/445 57/18722 0.746721107785848 0.809209049387024 APOE 1 GO:0001505 regulation of neurotransmitter levels 4/445 213/18722 0.748672400255674 0.810835065659117 WNT7A/RAP1B/CTBP2/SLC1A6 4 GO:0000956 nuclear-transcribed mRNA catabolic process 2/445 112/18722 0.749006683746113 0.810835065659117 SMG1/EIF4A3 2 GO:0009141 nucleoside triphosphate metabolic process 2/445 112/18722 0.749006683746113 0.810835065659117 TMSB4X/RHOA 2 GO:0043406 positive regulation of MAP kinase activity 2/445 112/18722 0.749006683746113 0.810835065659117 ARHGEF5/SASH1 2 GO:0043588 skin development 5/445 263/18722 0.75242641526851 0.813831471193083 CTNNB1/ANXA1/GRHL1/TXNIP/DSP 5 GO:0009161 ribonucleoside monophosphate metabolic process 1/445 58/18722 0.752759634816938 0.813831471193083 RFK 1 GO:0045604 regulation of epidermal cell differentiation 1/445 58/18722 0.752759634816938 0.813831471193083 GRHL1 1 GO:0097035 regulation of membrane lipid distribution 1/445 58/18722 0.752759634816938 0.813831471193083 PLSCR1 1 GO:2000649 regulation of sodium ion transmembrane transporter activity 1/445 58/18722 0.752759634816938 0.813831471193083 WNK1 1 GO:0002377 immunoglobulin production 4/445 216/18722 0.758335115127531 0.819132719154703 HLA-DRA/HLA-DRB1/HLA-DPA1/HLA-DPB1 4 GO:0032768 regulation of monooxygenase activity 1/445 59/18722 0.75865451064776 0.819132719154703 APOE 1 GO:0033013 tetrapyrrole metabolic process 1/445 59/18722 0.75865451064776 0.819132719154703 HMOX1 1 GO:0071806 protein transmembrane transport 1/445 59/18722 0.75865451064776 0.819132719154703 MCL1 1 GO:2001258 negative regulation of cation channel activity 1/445 59/18722 0.75865451064776 0.819132719154703 SRI 1 GO:0042471 ear morphogenesis 2/445 115/18722 0.761974582761569 0.822072865340309 OSR2/GATA3 2 GO:0051209 release of sequestered calcium ion into cytosol 2/445 115/18722 0.761974582761569 0.822072865340309 SRI/ERO1A 2 GO:0090630 activation of GTPase activity 2/445 115/18722 0.761974582761569 0.822072865340309 ARHGEF5/ARHGAP29 2 GO:0006289 nucleotide-excision repair 1/445 60/18722 0.764409145098906 0.824053804385068 HMGN1 1 GO:0031663 lipopolysaccharide-mediated signaling pathway 1/445 60/18722 0.764409145098906 0.824053804385068 SASH1 1 GO:0060038 cardiac muscle cell proliferation 1/445 60/18722 0.764409145098906 0.824053804385068 PIM1 1 GO:0007006 mitochondrial membrane organization 2/445 116/18722 0.766166536568505 0.825517465457614 BNIP3/BNIP3L 2 GO:0051283 negative regulation of sequestering of calcium ion 2/445 116/18722 0.766166536568505 0.825517465457614 SRI/ERO1A 2 GO:0000075 cell cycle checkpoint signaling 3/445 169/18722 0.769203934933997 0.828574043080141 SOX4/EIF2AK4/PLK2 3 GO:0030199 collagen fibril organization 1/445 61/18722 0.7700268672311 0.82881213875239 P4HA1 1 GO:0040014 regulation of multicellular organism growth 1/445 61/18722 0.7700268672311 0.82881213875239 PIK3CA 1 GO:0050994 regulation of lipid catabolic process 1/445 61/18722 0.7700268672311 0.82881213875239 APOC1 1 GO:0014902 myotube differentiation 2/445 117/18722 0.770294265824361 0.828883983360364 KLF5/MYOF 2 GO:0022612 gland morphogenesis 2/445 118/18722 0.774358447122098 0.832545644616717 CEBPB/SFRP1 2 GO:0030203 glycosaminoglycan metabolic process 2/445 118/18722 0.774358447122098 0.832545644616717 PIM1/HS6ST1 2 GO:0051282 regulation of sequestering of calcium ion 2/445 118/18722 0.774358447122098 0.832545644616717 SRI/ERO1A 2 GO:0007062 sister chromatid cohesion 1/445 62/18722 0.775510927253722 0.832545644616717 CTNNB1 1 GO:0007588 excretion 1/445 62/18722 0.775510927253722 0.832545644616717 HMOX1 1 GO:0031124 mRNA 3'-end processing 1/445 62/18722 0.775510927253722 0.832545644616717 YTHDC1 1 GO:0046847 filopodium assembly 1/445 62/18722 0.775510927253722 0.832545644616717 ZMYND8 1 GO:0060135 maternal process involved in female pregnancy 1/445 62/18722 0.775510927253722 0.832545644616717 SPP1 1 GO:0070265 necrotic cell death 1/445 62/18722 0.775510927253722 0.832545644616717 BNIP3 1 GO:0010906 regulation of glucose metabolic process 2/445 119/18722 0.778359761237382 0.835386898849474 PHLDA2/FAM3C 2 GO:1901136 carbohydrate derivative catabolic process 3/445 172/18722 0.779395022292721 0.836280736906813 MAN1A1/CST3/CDA 3 GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 5/445 273/18722 0.780481652894155 0.837229215296223 KLF4/MYADM/CLDN7/WNK1/CLDN19 5 GO:0001756 somitogenesis 1/445 63/18722 0.780864498388347 0.837422441028624 SFRP1 1 GO:0001659 temperature homeostasis 3/445 174/18722 0.785981552567614 0.840500838295571 CEBPB/PLCL2/ATF4 3 GO:0006749 glutathione metabolic process 1/445 64/18722 0.786090678688319 0.840500838295571 GSTP1 1 GO:0006940 regulation of smooth muscle contraction 1/445 64/18722 0.786090678688319 0.840500838295571 RHOA 1 GO:0016126 sterol biosynthetic process 1/445 64/18722 0.786090678688319 0.840500838295571 APOE 1 GO:0017156 calcium-ion regulated exocytosis 1/445 64/18722 0.786090678688319 0.840500838295571 RAP1B 1 GO:0030104 water homeostasis 1/445 64/18722 0.786090678688319 0.840500838295571 GRHL1 1 GO:0046530 photoreceptor cell differentiation 1/445 64/18722 0.786090678688319 0.840500838295571 THRB 1 GO:0046579 positive regulation of Ras protein signal transduction 1/445 64/18722 0.786090678688319 0.840500838295571 NET1 1 GO:0048247 lymphocyte chemotaxis 1/445 64/18722 0.786090678688319 0.840500838295571 WNK1 1 GO:0098930 axonal transport 1/445 64/18722 0.786090678688319 0.840500838295571 AP3S1 1 GO:0002224 toll-like receptor signaling pathway 2/445 121/18722 0.786176528485617 0.840500838295571 IRF1/CTSS 2 GO:0002455 humoral immune response mediated by circulating immunoglobulin 2/445 121/18722 0.786176528485617 0.840500838295571 C1QB/C1QA 2 GO:0050954 sensory perception of mechanical stimulus 3/445 175/18722 0.78921341194532 0.843529263841169 THRB/LRP2/NAV2 3 GO:0051928 positive regulation of calcium ion transport 2/445 122/18722 0.789993358993528 0.844115750986713 SRI/HSPA2 2 GO:0035418 protein localization to synapse 1/445 65/18722 0.791192492815433 0.844115750986713 WNT7A 1 GO:0043489 RNA stabilization 1/445 65/18722 0.791192492815433 0.844115750986713 YBX1 1 GO:0045682 regulation of epidermis development 1/445 65/18722 0.791192492815433 0.844115750986713 GRHL1 1 GO:0051310 metaphase plate congression 1/445 65/18722 0.791192492815433 0.844115750986713 CHMP5 1 GO:0061512 protein localization to cilium 1/445 65/18722 0.791192492815433 0.844115750986713 TMEM107 1 GO:0070613 regulation of protein processing 1/445 65/18722 0.791192492815433 0.844115750986713 GSN 1 GO:0071482 cellular response to light stimulus 2/445 123/18722 0.79375007603206 0.846625758866109 EIF2AK4/ATF4 2 GO:0019229 regulation of vasoconstriction 1/445 66/18722 0.796172893774705 0.848552689417778 RHOA 1 GO:0030193 regulation of blood coagulation 1/445 66/18722 0.796172893774705 0.848552689417778 APOE 1 GO:0050909 sensory perception of taste 1/445 66/18722 0.796172893774705 0.848552689417778 GNB1 1 GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger 1/445 67/18722 0.801034764608231 0.852469355388438 ANXA1 1 GO:0010517 regulation of phospholipase activity 1/445 67/18722 0.801034764608231 0.852469355388438 ANXA1 1 GO:0050435 amyloid-beta metabolic process 1/445 67/18722 0.801034764608231 0.852469355388438 APOE 1 GO:0018210 peptidyl-threonine modification 2/445 125/18722 0.801085944715061 0.852469355388438 GALNT1/WNK1 2 GO:0051053 negative regulation of DNA metabolic process 2/445 125/18722 0.801085944715061 0.852469355388438 HNRNPA1/GATA3 2 GO:0055007 cardiac muscle cell differentiation 2/445 125/18722 0.801085944715061 0.852469355388438 CALR/FHL2 2 GO:0007626 locomotory behavior 3/445 179/18722 0.801738370452584 0.852943911496169 APOE/UBA6/NAV2 3 GO:0007585 respiratory gaseous exchange by respiratory system 1/445 68/18722 0.805780920049096 0.855482133313497 YWHAZ 1 GO:0009206 purine ribonucleoside triphosphate biosynthetic process 1/445 68/18722 0.805780920049096 0.855482133313497 TMSB4X 1 GO:0009247 glycolipid biosynthetic process 1/445 68/18722 0.805780920049096 0.855482133313497 SCCPDH 1 GO:0042987 amyloid precursor protein catabolic process 1/445 68/18722 0.805780920049096 0.855482133313497 APOE 1 GO:0051148 negative regulation of muscle cell differentiation 1/445 68/18722 0.805780920049096 0.855482133313497 YBX1 1 GO:1900046 regulation of hemostasis 1/445 68/18722 0.805780920049096 0.855482133313497 APOE 1 GO:1901607 alpha-amino acid biosynthetic process 1/445 68/18722 0.805780920049096 0.855482133313497 PLOD2 1 GO:1902305 regulation of sodium ion transmembrane transport 1/445 68/18722 0.805780920049096 0.855482133313497 WNK1 1 GO:0044262 cellular carbohydrate metabolic process 5/445 283/18722 0.806027390060033 0.855523933283143 IMPA2/ISYNA1/PHLDA2/RB1CC1/FAM3C 5 GO:0006911 phagocytosis, engulfment 2/445 127/18722 0.808189692590912 0.857598669430531 GSN/AIF1 2 GO:0009145 purine nucleoside triphosphate biosynthetic process 1/445 69/18722 0.81041410813627 0.859296889299521 TMSB4X 1 GO:0019226 transmission of nerve impulse 1/445 69/18722 0.81041410813627 0.859296889299521 CLDN19 1 GO:0060193 positive regulation of lipase activity 1/445 69/18722 0.81041410813627 0.859296889299521 RHOA 1 GO:0006639 acylglycerol metabolic process 2/445 128/18722 0.81165625940192 0.860393124862543 APOE/APOC1 2 GO:0003407 neural retina development 1/445 70/18722 0.814937011791412 0.86268031922093 THRB 1 GO:0045123 cellular extravasation 1/445 70/18722 0.814937011791412 0.86268031922093 GOLPH3 1 GO:0006022 aminoglycan metabolic process 2/445 129/18722 0.815066881123043 0.86268031922093 PIM1/HS6ST1 2 GO:0006638 neutral lipid metabolic process 2/445 129/18722 0.815066881123043 0.86268031922093 APOE/APOC1 2 GO:0007093 mitotic cell cycle checkpoint signaling 2/445 129/18722 0.815066881123043 0.86268031922093 SOX4/PLK2 2 GO:0007498 mesoderm development 2/445 129/18722 0.815066881123043 0.86268031922093 KLF4/ETS2 2 GO:0060271 cilium assembly 6/445 337/18722 0.8154605675969 0.862875923346003 CENPJ/GSN/ODF2L/TMEM107/MAP4/WWTR1 6 GO:2001257 regulation of cation channel activity 3/445 184/18722 0.816511988847835 0.863767228151193 TMSB4X/SRI/CTSS 3 GO:0019318 hexose metabolic process 4/445 237/18722 0.81808264360492 0.865123418775221 PHLDA2/PIK3CA/FAM3C/ATF4 4 GO:0034660 ncRNA metabolic process 9/445 485/18722 0.818277076255342 0.865123418775221 MPHOSPH10/ZNHIT6/RIOK3/RPS15/SBDS/RBFA/EIF4A3/RPS19/RPS28 9 GO:0006282 regulation of DNA repair 2/445 130/18722 0.818422251409723 0.865123418775221 UBE2V1/UBE2V2 2 GO:0033555 multicellular organismal response to stress 1/445 71/18722 0.819352250358473 0.865442123812542 APOE 1 GO:0050818 regulation of coagulation 1/445 71/18722 0.819352250358473 0.865442123812542 APOE 1 GO:0071230 cellular response to amino acid stimulus 1/445 71/18722 0.819352250358473 0.865442123812542 CEBPB 1 GO:0001707 mesoderm formation 1/445 72/18722 0.823662381106984 0.868883885687679 KLF4 1 GO:0042273 ribosomal large subunit biogenesis 1/445 72/18722 0.823662381106984 0.868883885687679 ZNHIT6 1 GO:0051057 positive regulation of small GTPase mediated signal transduction 1/445 72/18722 0.823662381106984 0.868883885687679 NET1 1 GO:0055021 regulation of cardiac muscle tissue growth 1/445 72/18722 0.823662381106984 0.868883885687679 PIM1 1 GO:1905818 regulation of chromosome separation 1/445 72/18722 0.823662381106984 0.868883885687679 PLSCR1 1 GO:0035264 multicellular organism growth 2/445 132/18722 0.824970005510727 0.870041126567478 PIK3CA/WWTR1 2 GO:0042058 regulation of epidermal growth factor receptor signaling pathway 1/445 73/18722 0.827869900699874 0.872208763017388 CBL 1 GO:0045739 positive regulation of DNA repair 1/445 73/18722 0.827869900699874 0.872208763017388 UBE2V2 1 GO:0051145 smooth muscle cell differentiation 1/445 73/18722 0.827869900699874 0.872208763017388 CTNNB1 1 GO:0070988 demethylation 1/445 73/18722 0.827869900699874 0.872208763017388 GATA3 1 GO:0034765 regulation of ion transmembrane transport 9/445 491/18722 0.828916540428698 0.873088788503557 TMSB4X/SRI/GOPC/HSPA2/SESTD1/WNK1/CD63/CTSS/NDUFA4 9 GO:0042552 myelination 2/445 134/18722 0.831305039280829 0.874974034066882 CTNNB1/NDRG1 2 GO:0009201 ribonucleoside triphosphate biosynthetic process 1/445 74/18722 0.831977246626656 0.874974034066882 TMSB4X 1 GO:0010822 positive regulation of mitochondrion organization 1/445 74/18722 0.831977246626656 0.874974034066882 BNIP3 1 GO:0046323 glucose import 1/445 74/18722 0.831977246626656 0.874974034066882 SLC2A3 1 GO:0048332 mesoderm morphogenesis 1/445 74/18722 0.831977246626656 0.874974034066882 KLF4 1 GO:1901568 fatty acid derivative metabolic process 1/445 74/18722 0.831977246626656 0.874974034066882 HPGD 1 GO:0006024 glycosaminoglycan biosynthetic process 1/445 75/18722 0.8359867986028 0.878296405144498 HS6ST1 1 GO:0008088 axo-dendritic transport 1/445 75/18722 0.8359867986028 0.878296405144498 AP3S1 1 GO:0034121 regulation of toll-like receptor signaling pathway 1/445 75/18722 0.8359867986028 0.878296405144498 IRF1 1 GO:0036465 synaptic vesicle recycling 1/445 75/18722 0.8359867986028 0.878296405144498 WNT7A 1 GO:0006814 sodium ion transport 4/445 245/18722 0.837410357837381 0.879144864060301 NKAIN4/PKP2/WNK1/SLC13A4 4 GO:0007272 ensheathment of neurons 2/445 136/18722 0.837432834683439 0.879144864060301 CTNNB1/NDRG1 2 GO:0008366 axon ensheathment 2/445 136/18722 0.837432834683439 0.879144864060301 CTNNB1/NDRG1 2 GO:0008652 cellular amino acid biosynthetic process 1/445 76/18722 0.839900879936084 0.880170100206992 PLOD2 1 GO:0009123 nucleoside monophosphate metabolic process 1/445 76/18722 0.839900879936084 0.880170100206992 RFK 1 GO:0014823 response to activity 1/445 76/18722 0.839900879936084 0.880170100206992 CBL 1 GO:0014855 striated muscle cell proliferation 1/445 76/18722 0.839900879936084 0.880170100206992 PIM1 1 GO:0021536 diencephalon development 1/445 76/18722 0.839900879936084 0.880170100206992 UQCRQ 1 GO:0032720 negative regulation of tumor necrosis factor production 1/445 76/18722 0.839900879936084 0.880170100206992 GSTP1 1 GO:0140115 export across plasma membrane 1/445 76/18722 0.839900879936084 0.880170100206992 SLC40A1 1 GO:0007586 digestion 2/445 137/18722 0.840420719183934 0.880268253283172 LIMA1/WNK1 2 GO:0034754 cellular hormone metabolic process 2/445 137/18722 0.840420719183934 0.880268253283172 SPP1/HSD17B1 2 GO:0007224 smoothened signaling pathway 2/445 138/18722 0.843358829251862 0.883121755041684 SFRP1/CTNNA1 2 GO:0030705 cytoskeleton-dependent intracellular transport 3/445 195/18722 0.845750436769768 0.885401686339562 AP3S1/TANC2/ARHGAP21 3 GO:0016579 protein deubiquitination 2/445 139/18722 0.846247836338421 0.885473609907299 USP48/OTUD1 2 GO:0051783 regulation of nuclear division 2/445 139/18722 0.846247836338421 0.885473609907299 CALR/RGCC 2 GO:0035050 embryonic heart tube development 1/445 78/18722 0.847451649839893 0.886284244427493 CTNNB1 1 GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production 1/445 78/18722 0.847451649839893 0.886284244427493 GSTP1 1 GO:0001895 retina homeostasis 1/445 79/18722 0.851092714837814 0.889191705866214 LYZ 1 GO:0006023 aminoglycan biosynthetic process 1/445 79/18722 0.851092714837814 0.889191705866214 HS6ST1 1 GO:0051279 regulation of release of sequestered calcium ion into cytosol 1/445 79/18722 0.851092714837814 0.889191705866214 SRI 1 GO:1901184 regulation of ERBB signaling pathway 1/445 79/18722 0.851092714837814 0.889191705866214 CBL 1 GO:0035296 regulation of tube diameter 2/445 141/18722 0.851881208570472 0.889565539081047 APOE/RHOA 2 GO:0097746 blood vessel diameter maintenance 2/445 141/18722 0.851881208570472 0.889565539081047 APOE/RHOA 2 GO:0035150 regulation of tube size 2/445 142/18722 0.854626897220911 0.89132719608766 APOE/RHOA 2 GO:0046467 membrane lipid biosynthetic process 2/445 142/18722 0.854626897220911 0.89132719608766 PLPP3/SCCPDH 2 GO:0097553 calcium ion transmembrane import into cytosol 2/445 142/18722 0.854626897220911 0.89132719608766 SRI/ERO1A 2 GO:0007422 peripheral nervous system development 1/445 80/18722 0.854647064561419 0.89132719608766 NDRG1 1 GO:0051303 establishment of chromosome localization 1/445 80/18722 0.854647064561419 0.89132719608766 CHMP5 1 GO:0001523 retinoid metabolic process 1/445 81/18722 0.858116759673004 0.893592219362032 LRP2 1 GO:0001942 hair follicle development 1/445 81/18722 0.858116759673004 0.893592219362032 CTNNB1 1 GO:0006096 glycolytic process 1/445 81/18722 0.858116759673004 0.893592219362032 LDHA 1 GO:0051149 positive regulation of muscle cell differentiation 1/445 81/18722 0.858116759673004 0.893592219362032 MORF4L2 1 GO:0060968 regulation of gene silencing 1/445 81/18722 0.858116759673004 0.893592219362032 PPARG 1 GO:2000243 positive regulation of reproductive process 1/445 81/18722 0.858116759673004 0.893592219362032 CTNNB1 1 GO:0055074 calcium ion homeostasis 8/445 460/18722 0.858790976157744 0.894068932083579 APOE/SRI/ERO1A/BNIP3/TRIM24/GNB1/TMEM165/CALR 8 GO:0002312 B cell activation involved in immune response 1/445 82/18722 0.861503811974142 0.895313772896901 PLCL2 1 GO:0006757 ATP generation from ADP 1/445 82/18722 0.861503811974142 0.895313772896901 LDHA 1 GO:0007032 endosome organization 1/445 82/18722 0.861503811974142 0.895313772896901 CHMP5 1 GO:0050000 chromosome localization 1/445 82/18722 0.861503811974142 0.895313772896901 CHMP5 1 GO:0072527 pyrimidine-containing compound metabolic process 1/445 82/18722 0.861503811974142 0.895313772896901 CDA 1 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic 1/445 82/18722 0.861503811974142 0.895313772896901 RNASE1 1 GO:1905897 regulation of response to endoplasmic reticulum stress 1/445 82/18722 0.861503811974142 0.895313772896901 PPP1R15A 1 GO:0019722 calcium-mediated signaling 3/445 202/18722 0.862180919650998 0.89579209735369 FHL2/GBP1/CAMTA1 3 GO:0006643 membrane lipid metabolic process 3/445 203/18722 0.864398524845715 0.897749599240943 PLPP3/SCCPDH/PSAP 3 GO:0051899 membrane depolarization 1/445 83/18722 0.864810185561669 0.897749599240943 JUN 1 GO:0061053 somite development 1/445 83/18722 0.864810185561669 0.897749599240943 SFRP1 1 GO:0010675 regulation of cellular carbohydrate metabolic process 2/445 146/18722 0.865151574577147 0.897749599240943 PHLDA2/FAM3C 2 GO:0048813 dendrite morphogenesis 2/445 146/18722 0.865151574577147 0.897749599240943 WNT7A/TANC2 2 GO:0070588 calcium ion transmembrane transport 5/445 312/18722 0.866931926135392 0.89916352641871 SRI/ERO1A/HSPA2/SESTD1/TMEM165 5 GO:0006970 response to osmotic stress 1/445 84/18722 0.868037797956383 0.89916352641871 HSP90AB1 1 GO:0022404 molting cycle process 1/445 84/18722 0.868037797956383 0.89916352641871 CTNNB1 1 GO:0022405 hair cycle process 1/445 84/18722 0.868037797956383 0.89916352641871 CTNNB1 1 GO:0042310 vasoconstriction 1/445 84/18722 0.868037797956383 0.89916352641871 RHOA 1 GO:0042440 pigment metabolic process 1/445 84/18722 0.868037797956383 0.89916352641871 HMOX1 1 GO:1900542 regulation of purine nucleotide metabolic process 1/445 84/18722 0.868037797956383 0.89916352641871 TMSB4X 1 GO:0044272 sulfur compound biosynthetic process 2/445 148/18722 0.870148064176516 0.901123502911303 GSTP1/AMD1 2 GO:0009142 nucleoside triphosphate biosynthetic process 1/445 85/18722 0.87118852120509 0.901522991257071 TMSB4X 1 GO:0055013 cardiac muscle cell development 1/445 85/18722 0.87118852120509 0.901522991257071 FHL2 1 GO:0098773 skin epidermis development 1/445 85/18722 0.87118852120509 0.901522991257071 CTNNB1 1 GO:0044782 cilium organization 6/445 368/18722 0.873585420837577 0.903574015460071 CENPJ/GSN/ODF2L/TMEM107/MAP4/WWTR1 6 GO:0006493 protein O-linked glycosylation 1/445 86/18722 0.874264182956645 0.903574015460071 GALNT1 1 GO:0045921 positive regulation of exocytosis 1/445 86/18722 0.874264182956645 0.903574015460071 VAMP8 1 GO:1903510 mucopolysaccharide metabolic process 1/445 86/18722 0.874264182956645 0.903574015460071 PIM1 1 GO:2001251 negative regulation of chromosome organization 1/445 86/18722 0.874264182956645 0.903574015460071 HNRNPA1 1 GO:0007029 endoplasmic reticulum organization 1/445 87/18722 0.877266567512574 0.906057050043888 SHTN1 1 GO:0016101 diterpenoid metabolic process 1/445 87/18722 0.877266567512574 0.906057050043888 LRP2 1 GO:0055067 monovalent inorganic cation homeostasis 2/445 151/18722 0.877324667193307 0.906057050043888 CA2/TMEM165 2 GO:0006816 calcium ion transport 7/445 422/18722 0.877593784440627 0.906108453767616 CTNNB1/SRI/ERO1A/HSPA2/SESTD1/TMEM165/RHOA 7 GO:0031110 regulation of microtubule polymerization or depolymerization 1/445 88/18722 0.880197416852897 0.908342625285864 HSPA1B 1 GO:0070098 chemokine-mediated signaling pathway 1/445 88/18722 0.880197416852897 0.908342625285864 WNK1 1 GO:0009416 response to light stimulus 5/445 320/18722 0.880597792588449 0.908528841454267 FOS/JUND/HMGN1/EIF2AK4/ATF4 5 GO:0120254 olefinic compound metabolic process 2/445 153/18722 0.881904165437393 0.909649465024187 HSD17B1/GSTP1 2 GO:0030258 lipid modification 3/445 212/18722 0.882984646016547 0.910536588291152 APOE/APOC1/PLPP3 3 GO:0016052 carbohydrate catabolic process 2/445 154/18722 0.884134257696339 0.911494539192307 LDHA/RB1CC1 2 GO:0043583 ear development 3/445 213/18722 0.884903392384559 0.912059858767618 OSR2/SPARC/GATA3 3 GO:0046031 ADP metabolic process 1/445 90/18722 0.885851272185204 0.912614683746548 LDHA 1 GO:0006665 sphingolipid metabolic process 2/445 155/18722 0.886325371869075 0.912614683746548 PLPP3/PSAP 2 GO:0010970 transport along microtubule 2/445 155/18722 0.886325371869075 0.912614683746548 AP3S1/ARHGAP21 2 GO:0051147 regulation of muscle cell differentiation 2/445 155/18722 0.886325371869075 0.912614683746548 YBX1/MORF4L2 2 GO:0035051 cardiocyte differentiation 2/445 156/18722 0.888478095615204 0.913567421102632 CALR/FHL2 2 GO:0019935 cyclic-nucleotide-mediated signaling 1/445 91/18722 0.88857755942638 0.913567421102632 APOE 1 GO:0042147 retrograde transport, endosome to Golgi 1/445 91/18722 0.88857755942638 0.913567421102632 SNX2 1 GO:0051983 regulation of chromosome segregation 1/445 91/18722 0.88857755942638 0.913567421102632 PLSCR1 1 GO:0055006 cardiac cell development 1/445 91/18722 0.88857755942638 0.913567421102632 FHL2 1 GO:0098661 inorganic anion transmembrane transport 1/445 91/18722 0.88857755942638 0.913567421102632 SLC13A4 1 GO:0070646 protein modification by small protein removal 2/445 157/18722 0.890593010754001 0.915411726156949 USP48/OTUD1 2 GO:0070509 calcium ion import 1/445 92/18722 0.891238875837483 0.915847710468817 CTNNB1 1 GO:0010389 regulation of G2/M transition of mitotic cell cycle 1/445 94/18722 0.896372739240562 0.920665287370155 HSPA2 1 GO:0032091 negative regulation of protein binding 1/445 94/18722 0.896372739240562 0.920665287370155 GOLGA2 1 GO:0060402 calcium ion transport into cytosol 2/445 160/18722 0.896716634003035 0.920789563774928 SRI/ERO1A 2 GO:0008593 regulation of Notch signaling pathway 1/445 95/18722 0.898848266996518 0.922749053420133 EPN2 1 GO:0042472 inner ear morphogenesis 1/445 96/18722 0.901264787165442 0.924311031723049 GATA3 1 GO:0043648 dicarboxylic acid metabolic process 1/445 96/18722 0.901264787165442 0.924311031723049 MTHFD1L 1 GO:0051304 chromosome separation 1/445 96/18722 0.901264787165442 0.924311031723049 PLSCR1 1 GO:0055017 cardiac muscle tissue growth 1/445 96/18722 0.901264787165442 0.924311031723049 PIM1 1 GO:0006721 terpenoid metabolic process 1/445 97/18722 0.9036237031813 0.92604056508111 LRP2 1 GO:0043255 regulation of carbohydrate biosynthetic process 1/445 97/18722 0.9036237031813 0.92604056508111 FAM3C 1 GO:0120162 positive regulation of cold-induced thermogenesis 1/445 97/18722 0.9036237031813 0.92604056508111 CEBPB 1 GO:0006631 fatty acid metabolic process 6/445 390/18722 0.90485234325007 0.927069699892371 APOC1/CD74/ANXA1/GSTP1/HPGD/PPARG 6 GO:0016485 protein processing 3/445 225/18722 0.905831058895175 0.927709939798514 GSN/SRGN/CTSS 3 GO:0043473 pigmentation 1/445 98/18722 0.905926385172405 0.927709939798514 CD63 1 GO:0006165 nucleoside diphosphate phosphorylation 1/445 99/18722 0.908174170750062 0.929781288567163 LDHA 1 GO:0006664 glycolipid metabolic process 1/445 100/18722 0.910368365778587 0.931796758927488 SCCPDH 1 GO:0006874 cellular calcium ion homeostasis 7/445 448/18722 0.911055165024935 0.932268735872679 APOE/SRI/ERO1A/BNIP3/GNB1/TMEM165/CALR 7 GO:0046939 nucleotide phosphorylation 1/445 101/18722 0.912510245127128 0.933295326224354 LDHA 1 GO:1903509 liposaccharide metabolic process 1/445 101/18722 0.912510245127128 0.933295326224354 SCCPDH 1 GO:0006672 ceramide metabolic process 1/445 102/18722 0.91460105340372 0.93427718882561 PLPP3 1 GO:0010522 regulation of calcium ion transport into cytosol 1/445 102/18722 0.91460105340372 0.93427718882561 SRI 1 GO:0034308 primary alcohol metabolic process 1/445 102/18722 0.91460105340372 0.93427718882561 GDPD3 1 GO:1902749 regulation of cell cycle G2/M phase transition 1/445 102/18722 0.91460105340372 0.93427718882561 HSPA2 1 GO:1990542 mitochondrial transmembrane transport 1/445 102/18722 0.91460105340372 0.93427718882561 SLC25A37 1 GO:0009135 purine nucleoside diphosphate metabolic process 1/445 103/18722 0.916642005671999 0.935436789879206 LDHA 1 GO:0009179 purine ribonucleoside diphosphate metabolic process 1/445 103/18722 0.916642005671999 0.935436789879206 LDHA 1 GO:0030148 sphingolipid biosynthetic process 1/445 103/18722 0.916642005671999 0.935436789879206 PLPP3 1 GO:0050773 regulation of dendrite development 1/445 103/18722 0.916642005671999 0.935436789879206 RHOA 1 GO:0007059 chromosome segregation 5/445 346/18722 0.917041717702218 0.935613567752003 CTNNB1/RIOK3/CHMP5/BEX4/PLSCR1 5 GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 3/445 233/18722 0.917807008671116 0.936163148844539 GNB1/AKAP12/PSAP 3 GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway 1/445 104/18722 0.91863428815097 0.936775671279105 GNB1 1 GO:0006090 pyruvate metabolic process 1/445 106/18722 0.922477448477142 0.940230530387139 LDHA 1 GO:0009185 ribonucleoside diphosphate metabolic process 1/445 106/18722 0.922477448477142 0.940230530387139 LDHA 1 GO:0042303 molting cycle 1/445 107/18722 0.924330560607979 0.941654635233431 CTNNB1 1 GO:0042633 hair cycle 1/445 107/18722 0.924330560607979 0.941654635233431 CTNNB1 1 GO:0071466 cellular response to xenobiotic stimulus 2/445 177/18722 0.925794172287863 0.942799941388231 RAP1B/GSTP1 2 GO:0098659 inorganic cation import across plasma membrane 1/445 108/18722 0.926139472804028 0.942799941388231 WNK1 1 GO:0099587 inorganic ion import across plasma membrane 1/445 108/18722 0.926139472804028 0.942799941388231 WNK1 1 GO:0006109 regulation of carbohydrate metabolic process 2/445 178/18722 0.927238800384428 0.943686495291469 PHLDA2/FAM3C 2 GO:0007416 synapse assembly 2/445 179/18722 0.92865688433846 0.944896943153246 WNT7A/UBE2V2 2 GO:0006939 smooth muscle contraction 1/445 110/18722 0.929628880120227 0.945187522465335 RHOA 1 GO:0007088 regulation of mitotic nuclear division 1/445 110/18722 0.929628880120227 0.945187522465335 RGCC 1 GO:1904659 glucose transmembrane transport 1/445 110/18722 0.929628880120227 0.945187522465335 SLC2A3 1 GO:0015698 inorganic anion transport 2/445 180/18722 0.930048866110154 0.945381856766989 CEBPB/SLC13A4 2 GO:0006805 xenobiotic metabolic process 1/445 111/18722 0.931311404746624 0.946432327923322 GSTP1 1 GO:0009260 ribonucleotide biosynthetic process 2/445 182/18722 0.932756261210175 0.947169354859252 TMSB4X/RFK 2 GO:0051260 protein homooligomerization 2/445 182/18722 0.932756261210175 0.947169354859252 RNF213/GOLGA2 2 GO:0060401 cytosolic calcium ion transport 2/445 182/18722 0.932756261210175 0.947169354859252 SRI/ERO1A 2 GO:0001676 long-chain fatty acid metabolic process 1/445 112/18722 0.932953789620502 0.947169354859252 GSTP1 1 GO:0008645 hexose transmembrane transport 1/445 114/18722 0.936121939427547 0.950152268249434 SLC2A3 1 GO:0006720 isoprenoid metabolic process 1/445 116/18722 0.939140704438927 0.952280375561415 LRP2 1 GO:0015749 monosaccharide transmembrane transport 1/445 116/18722 0.939140704438927 0.952280375561415 SLC2A3 1 GO:0018107 peptidyl-threonine phosphorylation 1/445 116/18722 0.939140704438927 0.952280375561415 WNK1 1 GO:0031123 RNA 3'-end processing 1/445 116/18722 0.939140704438927 0.952280375561415 YTHDC1 1 GO:0048839 inner ear development 2/445 188/18722 0.940296128023502 0.953217988923947 SPARC/GATA3 2 GO:0019932 second-messenger-mediated signaling 4/445 312/18722 0.941124881374856 0.953824064023438 APOE/FHL2/GBP1/CAMTA1 4 GO:0034219 carbohydrate transmembrane transport 1/445 118/18722 0.942017113339993 0.954408908950432 SLC2A3 1 GO:0009566 fertilization 2/445 190/18722 0.942626082914007 0.954408908950432 IGSF8/FNDC3A 2 GO:0046390 ribose phosphate biosynthetic process 2/445 190/18722 0.942626082914007 0.954408908950432 TMSB4X/RFK 2 GO:0099111 microtubule-based transport 2/445 190/18722 0.942626082914007 0.954408908950432 AP3S1/ARHGAP21 2 GO:0042752 regulation of circadian rhythm 1/445 121/18722 0.946079375957798 0.957670644959976 PPARG 1 GO:1901605 alpha-amino acid metabolic process 2/445 195/18722 0.948078954827121 0.959400417210779 PLOD2/ATF4 2 GO:0016042 lipid catabolic process 4/445 320/18722 0.948252699944713 0.959400417210779 APOE/APOC1/SPP1/GDPD3 4 GO:0006260 DNA replication 3/445 260/18722 0.948680290565365 0.95959801183289 TSPYL2/JUN/PTMS 3 GO:0090305 nucleic acid phosphodiester bond hydrolysis 3/445 261/18722 0.949584298018701 0.960083650416986 DFFB/RNASE1/PLSCR1 3 GO:0007368 determination of left/right symmetry 1/445 124/18722 0.949857632353963 0.960083650416986 TMEM107 1 GO:0009132 nucleoside diphosphate metabolic process 1/445 124/18722 0.949857632353963 0.960083650416986 LDHA 1 GO:0072522 purine-containing compound biosynthetic process 2/445 200/18722 0.953036197341167 0.963060795307329 TMSB4X/AMD1 2 GO:0000819 sister chromatid segregation 2/445 202/18722 0.954889832080258 0.964697944808889 CTNNB1/CHMP5 2 GO:0006612 protein targeting to membrane 1/445 131/18722 0.957677826554248 0.967041579441603 RAB8B 1 GO:0050853 B cell receptor signaling pathway 1/445 131/18722 0.957677826554248 0.967041579441603 PLCL2 1 GO:0009581 detection of external stimulus 1/445 135/18722 0.961587095398808 0.970751781791906 CTNNB1 1 GO:0009582 detection of abiotic stimulus 1/445 138/18722 0.964280693433423 0.973233213919733 CTNNB1 1 GO:0044242 cellular lipid catabolic process 2/445 214/18722 0.96462532046299 0.973343233715831 APOC1/GDPD3 2 GO:0007601 visual perception 2/445 215/18722 0.965338637944281 0.97382513146467 EFEMP1/CLDN19 2 GO:0006520 cellular amino acid metabolic process 3/445 284/18722 0.966695397817591 0.974955734468864 PTS/PLOD2/ATF4 3 GO:0050953 sensory perception of light stimulus 2/445 219/18722 0.968056196414204 0.975851670909487 EFEMP1/CLDN19 2 GO:0071805 potassium ion transmembrane transport 2/445 219/18722 0.968056196414204 0.975851670909487 WNK1/CD63 2 GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway 1/445 146/18722 0.97057746324075 0.978154550048192 GNB1 1 GO:0008037 cell recognition 2/445 225/18722 0.971751897716364 0.979080530484717 YWHAZ/CNTNAP3 2 GO:0050905 neuromuscular process 1/445 148/18722 0.971970286980834 0.979080530484717 TNNI2 1 GO:0007411 axon guidance 2/445 227/18722 0.972889595422001 0.979767654482761 SEMA4C/GATA3 2 GO:0097485 neuron projection guidance 2/445 228/18722 0.973441752619365 0.980018062410114 SEMA4C/GATA3 2 GO:0048754 branching morphogenesis of an epithelial tube 1/445 151/18722 0.973937135114192 0.980018062410114 CTNNB1 1 GO:0016197 endosomal transport 2/445 230/18722 0.9745137131756 0.980018062410114 SNX2/CHMP5 2 GO:0008643 carbohydrate transport 1/445 152/18722 0.974561655865589 0.980018062410114 SLC2A3 1 GO:0050871 positive regulation of B cell activation 1/445 152/18722 0.974561655865589 0.980018062410114 CD74 1 GO:0090501 RNA phosphodiester bond hydrolysis 1/445 152/18722 0.974561655865589 0.980018062410114 RNASE1 1 GO:0007338 single fertilization 1/445 153/18722 0.975171244618406 0.980392409714927 IGSF8 1 GO:0006813 potassium ion transport 2/445 241/18722 0.979702555855038 0.984708335337509 WNK1/CD63 2 GO:0007204 positive regulation of cytosolic calcium ion concentration 3/445 319/18722 0.982617795844766 0.987047341096539 SRI/ERO1A/GNB1 3 GO:0009259 ribonucleotide metabolic process 4/445 385/18722 0.982731849310704 0.987047341096539 TMSB4X/RFK/LDHA/RHOA 4 GO:0000070 mitotic sister chromatid segregation 1/445 168/18722 0.98274648122248 0.987047341096539 CHMP5 1 GO:0009152 purine ribonucleotide biosynthetic process 1/445 169/18722 0.983160290420281 0.987222936248464 TMSB4X 1 GO:0009165 nucleotide biosynthetic process 2/445 254/18722 0.984523857698588 0.988351896999481 TMSB4X/RFK 2 GO:1901293 nucleoside phosphate biosynthetic process 2/445 256/18722 0.985159192130811 0.988749422422833 TMSB4X/RFK 2 GO:0019693 ribose phosphate metabolic process 4/445 396/18722 0.985768058399195 0.989120196562321 TMSB4X/RFK/LDHA/RHOA 4 GO:0035725 sodium ion transmembrane transport 1/445 178/18722 0.986466162644725 0.989580310316988 WNK1 1 GO:0072521 purine-containing compound metabolic process 4/445 416/18722 0.99003641783442 0.992775283457674 TMSB4X/LDHA/AMD1/RHOA 4 GO:0006164 purine nucleotide biosynthetic process 1/445 191/18722 0.990131727873546 0.992775283457674 TMSB4X 1 GO:0051480 regulation of cytosolic calcium ion concentration 3/445 353/18722 0.990932632233223 0.993297163119917 SRI/ERO1A/GNB1 3 GO:0098813 nuclear chromosome segregation 2/445 281/18722 0.991247786045415 0.993297163119917 CTNNB1/CHMP5 2 GO:0009117 nucleotide metabolic process 5/445 489/18722 0.991373566580348 0.993297163119917 TMSB4X/RFK/LDHA/RHOA/CDA 5 GO:0006753 nucleoside phosphate metabolic process 5/445 497/18722 0.992478662605542 0.994163277212292 TMSB4X/RFK/LDHA/RHOA/CDA 5 GO:0009150 purine ribonucleotide metabolic process 3/445 368/18722 0.993231056978026 0.994675756697267 TMSB4X/LDHA/RHOA 3 GO:0044282 small molecule catabolic process 3/445 376/18722 0.994215234890886 0.995420052189591 APOE/IMPA2/CDA 3 GO:0006163 purine nucleotide metabolic process 3/445 396/18722 0.996107767994212 0.997073222579135 TMSB4X/LDHA/RHOA 3 GO:0006790 sulfur compound metabolic process 2/445 339/18722 0.997492987178527 0.998193253751303 GSTP1/AMD1 2 GO:0006302 double-strand break repair 1/445 251/18722 0.997709984202162 0.998193253751303 UBE2V2 1 GO:0006310 DNA recombination 1/445 305/18722 0.999387522694069 0.999629505145085 HMGB3 1 GO:0007608 sensory perception of smell 1/445 456/18722 0.999984987722804 0.999984987722804 NAV2 1