ID Description GeneRatio BgRatio pvalue p.adjust geneID Count GO:0003735 structural constituent of ribosome 30/221 182/18367 1.36052984417951e-25 5.79585713620472e-23 RPL39/RPS27/RPL34/RPS29/RPS28/RPL37A/RPL12/RPS14/RPL37/RPL36/RPLP1/RPS12/RPS15A/RPL28/RPLP2/RPL30/RPS13/UBA52/RPS15/RPL32/RPL3/MRPL3/RPS18/RPS23/RPS5/RPL35A/RPL18A/RPS24/RPL31/RPL21 30 GO:0045296 cadherin binding 18/221 332/18367 1.17606689986681e-07 2.5050224967163e-05 HSPA1A/LDHA/FLNB/RPL34/ANXA1/PRDX1/EGFR/PKM/PKP3/HNRNPK/HSP90AB1/ZC3H15/EZR/PCBP1/ALDOA/RSL1D1/CRKL/AHSA1 18 GO:0097718 disordered domain specific binding 6/221 36/18367 4.08498047988168e-06 0.000580067228143198 HSPA1A/HSP90AA1/GJA5/HSP90AB1/PPIL1/EZR 6 GO:0023026 MHC class II protein complex binding 5/221 27/18367 1.56809061616108e-05 0.00122603176580499 CD81/CD74/HSP90AA1/PKM/HSP90AB1 5 GO:0051082 unfolded protein binding 9/221 122/18367 1.68939977495913e-05 0.00122603176580499 HSPA1A/HSPA1B/NPM1/HSP90AA1/PTGES3/HSP90AB1/TUBB4B/DNAJA1/CCT3 9 GO:0019843 rRNA binding 7/221 68/18367 1.72680530395068e-05 0.00122603176580499 NPM1/RPL12/RPS14/RPL37/RPS13/RPS18/RPS5 7 GO:0023023 MHC protein complex binding 5/221 36/18367 6.70515946265938e-05 0.00408056847298985 CD81/CD74/HSP90AA1/PKM/HSP90AB1 5 GO:0044183 protein folding chaperone 5/221 40/18367 0.000112546627494187 0.00599310791406548 HSPA1A/HSPA1B/CD74/HSP90AB1/CCT3 5 GO:0042826 histone deacetylase binding 8/221 127/18367 0.000152130368713091 0.00694695359930698 HSPA1A/HSPA1B/SFPQ/HSP90AA1/HSP90AB1/KLF4/CDC20/KPNA2 8 GO:0031072 heat shock protein binding 8/221 129/18367 0.000169492265884106 0.00694695359930698 HSPA1A/HSPA1B/PTGES3/STIP1/HSP90AB1/CHORDC1/DNAJA1/AHSA1 8 GO:0030957 Tat protein binding 3/221 10/18367 0.000193755708968691 0.00694695359930698 NPM1/ACTB/DNAJA1 3 GO:0004857 enzyme inhibitor activity 6/221 70/18367 0.000195688833783295 0.00694695359930698 ANXA1/RPL37/DYNLL1/RPS15/ANXA5/ANXA4 6 GO:0005536 glucose binding 3/221 11/18367 0.000264051426240933 0.00865276212143365 SLC2A3/UGP2/PYGL 3 GO:0048027 mRNA 5'-UTR binding 4/221 27/18367 0.000288055948372944 0.008765131000491 RPS14/RPS13/GNL3/RSL1D1 4 GO:0004859 phospholipase inhibitor activity 3/221 13/18367 0.000449614018753903 0.0127690381326108 ANXA1/ANXA5/ANXA4 3 GO:0050998 nitric-oxide synthase binding 3/221 15/18367 0.00070268923061262 0.0176085654259398 ACTB/CD74/CAV1 3 GO:0098847 sequence-specific single stranded DNA binding 3/221 15/18367 0.00070268923061262 0.0176085654259398 HNRNPA1/HNRNPA2B1/PCBP1 3 GO:0140678 molecular function inhibitor activity 7/221 128/18367 0.000916943215566154 0.0217009894350656 ANXA1/RPL37/CAV1/DYNLL1/RPS15/ANXA5/ANXA4 7 GO:0055102 lipase inhibitor activity 3/221 18/18367 0.00122708849489305 0.027512615727602 ANXA1/ANXA5/ANXA4 3 GO:0005200 structural constituent of cytoskeleton 6/221 103/18367 0.001537260798245 0.0325926438743111 KRT19/DSP/ACTG1/ACTB/TUBA1C/TUBB4B 6 GO:0044389 ubiquitin-like protein ligase binding 11/221 316/18367 0.00160667962760689 0.0325926438743111 HSPA1A/ACTG1/HSPA1B/UBASH3B/EGFR/JUN/HSP90AA1/UBA52/HSP90AB1/CCNB1/DNAJA1 11 GO:0051879 Hsp90 protein binding 4/221 44/18367 0.00189938814693061 0.0352664774931659 PTGES3/STIP1/CHORDC1/AHSA1 4 GO:0003725 double-stranded RNA binding 5/221 74/18367 0.00197972998575752 0.0352664774931659 EIF4A1/TFRC/HSP90AB1/ILF3/TUBB4B 5 GO:0048156 tau protein binding 4/221 45/18367 0.00206527792130982 0.0352664774931659 ACTB/HSP90AA1/HSP90AB1/LGMN 4 GO:0001618 virus receptor activity 5/221 76/18367 0.00222701049397894 0.0352664774931659 HSPA1A/HSPA1B/CD81/EGFR/TFRC 5 GO:0055106 ubiquitin-protein transferase regulator activity 3/221 22/18367 0.00223519927773587 0.0352664774931659 RPL37/RPS15/CDC20 3 GO:0070182 DNA polymerase binding 3/221 22/18367 0.00223519927773587 0.0352664774931659 HSP90AA1/PTGES3/HSP90AB1 3 GO:0140272 exogenous protein binding 5/221 77/18367 0.00235874629863315 0.0358866401149186 HSPA1A/HSPA1B/CD81/EGFR/TFRC 5 GO:0140297 DNA-binding transcription factor binding 12/221 394/18367 0.00303488117231292 0.0434787692416872 ISL1/NPM1/ACTB/RBFOX2/ATF4/JUN/PTMA/KLF5/KLF4/TCERG1/DNAJA1/ANXA4 12 GO:0003730 mRNA 3'-UTR binding 8/221 201/18367 0.00306188515786529 0.0434787692416872 PABPC4/YBX3/HNRNPA2B1/ILF3/HNRNPR/HNRNPA0/RSL1D1/DAZAP1 8 GO:0031625 ubiquitin protein ligase binding 10/221 297/18367 0.00328945024511282 0.0452034130457439 HSPA1A/ACTG1/HSPA1B/UBASH3B/EGFR/JUN/HSP90AA1/UBA52/HSP90AB1/DNAJA1 10 GO:0003727 single-stranded RNA binding 5/221 87/18367 0.00400525336043662 0.0533199353608125 ANXA1/HNRNPA1/PABPC4/ILF3/DAZAP1 5 GO:0008330 protein tyrosine/threonine phosphatase activity 2/221 10/18367 0.00608607754443241 0.0762549715861237 DUSP5/DUSP9 2 GO:0098505 G-rich strand telomeric DNA binding 2/221 10/18367 0.00608607754443241 0.0762549715861237 HNRNPA1/HNRNPA2B1 2 GO:0097371 MDM2/MDM4 family protein binding 2/221 11/18367 0.00737986112625274 0.0873283566606574 RPL37/RPS15 2 GO:0099186 structural constituent of postsynapse 2/221 11/18367 0.00737986112625274 0.0873283566606574 ACTG1/ACTB 2 GO:0097110 scaffold protein binding 4/221 67/18367 0.00865600651401129 0.0959706316500291 KRT8/DSP/DYNLL1/HSP90AA1 4 GO:0043047 single-stranded telomeric DNA binding 2/221 12/18367 0.00878604374260829 0.0959706316500291 HNRNPA1/HNRNPA2B1 2 GO:0043422 protein kinase B binding 2/221 12/18367 0.00878604374260829 0.0959706316500291 SRSF5/SRSF1 2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 2/221 13/18367 0.0103017582378546 0.104753427647603 DUSP5/DUSP9 2 GO:0072542 protein phosphatase activator activity 2/221 13/18367 0.0103017582378546 0.104753427647603 IGFBP3/PPP1R15A 2 GO:0061629 RNA polymerase II-specific DNA-binding transcription factor binding 9/221 299/18367 0.0104682389728159 0.104753427647603 ISL1/NPM1/ACTB/ATF4/JUN/KLF4/TCERG1/DNAJA1/ANXA4 9 GO:0048029 monosaccharide binding 4/221 71/18367 0.0105737027907205 0.104753427647603 SLC2A3/UGP2/PYGL/ALDOA 4 GO:0071837 HMG box domain binding 2/221 14/18367 0.0119241896371262 0.115447836032176 JUN/DLX5 2 GO:0042287 MHC protein binding 3/221 40/18367 0.0122390792824652 0.115863283874004 CD81/CD74/TUBB4B 3 GO:1990825 sequence-specific mRNA binding 2/221 15/18367 0.0136505743150514 0.126416188221997 SRSF3/ETF1 2 GO:0005521 lamin binding 2/221 16/18367 0.0154781991767724 0.140291762751171 SUN2/SYNE1 2 GO:0003697 single-stranded DNA binding 5/221 123/18367 0.0165859668505036 0.147200455798219 ANXA1/HNRNPA1/HNRNPA2B1/PCBP1/NUCKS1 5 GO:0008135 translation factor activity, RNA binding 4/221 84/18367 0.0186233780242346 0.159148397029544 EIF4A1/EIF5A/EIF3A/ETF1 4 GO:0033549 MAP kinase phosphatase activity 2/221 18/18367 0.0194265648956251 0.159148397029544 DUSP5/DUSP9 2 GO:0098641 cadherin binding involved in cell-cell adhesion 2/221 18/18367 0.0194265648956251 0.159148397029544 ANXA1/PKP3 2 GO:0098918 structural constituent of synapse 2/221 18/18367 0.0194265648956251 0.159148397029544 ACTG1/ACTB 2 GO:0098632 cell-cell adhesion mediator activity 3/221 49/18367 0.0210988029384952 0.169586604750924 ANXA1/DSP/PKP3 3 GO:0004601 peroxidase activity 3/221 51/18367 0.0234370744252748 0.183943409680004 GPX3/PRDX1/HBG1 3 GO:0019211 phosphatase activator activity 2/221 20/18367 0.0237485622826296 0.183943409680004 IGFBP3/PPP1R15A 2 GO:0016830 carbon-carbon lyase activity 3/221 52/18367 0.0246567892555072 0.187567718265108 AMD1/ALDOA/AZIN1 3 GO:0005544 calcium-dependent phospholipid binding 3/221 54/18367 0.0271972467643075 0.200012149413057 ANXA1/ANXA5/ANXA4 3 GO:0045182 translation regulator activity 5/221 140/18367 0.0272317010937965 0.200012149413057 RPS14/EIF4A1/EIF5A/EIF3A/ETF1 5 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 3/221 55/18367 0.0285178911410286 0.205908841119969 GPX3/PRDX1/HBG1 3 GO:0043495 protein-membrane adaptor activity 2/221 24/18367 0.0334343202712528 0.23274422853 SUN2/SYNE1 2 GO:0098631 cell adhesion mediator activity 3/221 59/18367 0.034134753963146 0.23274422853 ANXA1/DSP/PKP3 3 GO:0043021 ribonucleoprotein complex binding 5/221 149/18367 0.0343001652996346 0.23274422853 NPM1/RPLP1/YBX3/EIF5A/ETF1 5 GO:0004725 protein tyrosine phosphatase activity 4/221 102/18367 0.0347777681014891 0.23274422853 UBASH3B/DUSP5/PTPRG/DUSP9 4 GO:0008238 exopeptidase activity 4/221 103/18367 0.0358542032002432 0.23274422853 DPP7/TFRC/MME/BLMH 4 GO:0008266 poly(U) RNA binding 2/221 25/18367 0.0360589649835212 0.23274422853 PABPC4/DAZAP1 2 GO:0035925 mRNA 3'-UTR AU-rich region binding 2/221 25/18367 0.0360589649835212 0.23274422853 ILF3/HNRNPA0 2 GO:0051087 chaperone binding 4/221 107/18367 0.0403512935458061 0.252777424633436 PTGES3/STIP1/DNAJA1/AHSA1 4 GO:0090079 translation regulator activity, nucleic acid binding 4/221 108/18367 0.0415234564856189 0.252777424633436 EIF4A1/EIF5A/EIF3A/ETF1 4 GO:0001671 ATPase activator activity 2/221 27/18367 0.0415361965360106 0.252777424633436 DNAJA1/AHSA1 2 GO:0043425 bHLH transcription factor binding 2/221 27/18367 0.0415361965360106 0.252777424633436 ISL1/KLF5 2 GO:0047485 protein N-terminus binding 4/221 110/18367 0.0439252626828464 0.261701418293275 HSPA1A/HSPA1B/NPM1/EIF5A 4 GO:0008187 poly-pyrimidine tract binding 2/221 28/18367 0.0443844090551583 0.261701418293275 PABPC4/DAZAP1 2 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 10/221 450/18367 0.0462561657686891 0.261701418293275 ISL1/FOSB/ATF4/JUN/ZNF395/MAFF/DLX5/KLF5/KLF4/UBP1 10 GO:0035250 UDP-galactosyltransferase activity 2/221 29/18367 0.0473028385177986 0.261701418293275 B3GNT2/COLGALT1 2 GO:0051059 NF-kappaB binding 2/221 29/18367 0.0473028385177986 0.261701418293275 NPM1/ANXA4 2 GO:0051787 misfolded protein binding 2/221 29/18367 0.0473028385177986 0.261701418293275 HSPA1A/HSPA1B 2 GO:0070717 poly-purine tract binding 2/221 29/18367 0.0473028385177986 0.261701418293275 PABPC4/DAZAP1 2 GO:0001216 DNA-binding transcription activator activity 10/221 456/18367 0.0497629921329497 0.271782495495341 ISL1/FOSB/ATF4/JUN/ZNF395/MAFF/DLX5/KLF5/KLF4/UBP1 10 GO:0008378 galactosyltransferase activity 2/221 32/18367 0.0564587742920833 0.304448580359842 B3GNT2/COLGALT1 2 GO:0016831 carboxy-lyase activity 2/221 34/18367 0.0628766319906115 0.32748350744512 AMD1/AZIN1 2 GO:0035198 miRNA binding 2/221 34/18367 0.0628766319906115 0.32748350744512 HNRNPA1/HNRNPA2B1 2 GO:0019207 kinase regulator activity 6/221 233/18367 0.0630367314800466 0.32748350744512 NPM1/RPLP1/HSP90AB1/KLF4/CCNB1/CCNL1 6 GO:0042162 telomeric DNA binding 2/221 36/18367 0.0695276755537851 0.356852888986897 HNRNPA1/HNRNPA2B1 2 GO:0046915 transition metal ion transmembrane transporter activity 2/221 37/18367 0.0729360217904435 0.369889824794392 SLC40A1/SLC25A37 2 GO:0004177 aminopeptidase activity 2/221 40/18367 0.0834710312214732 0.413472782562181 DPP7/BLMH 2 GO:0031492 nucleosomal DNA binding 2/221 40/18367 0.0834710312214732 0.413472782562181 ACTB/MBD3 2 GO:0016209 antioxidant activity 3/221 86/18367 0.0852587855712856 0.417474053486985 GPX3/PRDX1/HBG1 3 GO:0051117 ATPase binding 3/221 89/18367 0.0922321746097787 0.446487572542792 EGFR/CAV1/EZR 3 GO:0042277 peptide binding 7/221 321/18367 0.0937492521389684 0.446993697046614 SLC40A1/CD74/HSP90AB1/ITM2B/PPIL1/MME/KPNA2 7 GO:0030544 Hsp70 protein binding 2/221 43/18367 0.0944352881084397 0.446993697046614 STIP1/DNAJA1 2 GO:0019887 protein kinase regulator activity 5/221 204/18367 0.100494905970379 0.456757790705226 NPM1/RPLP1/HSP90AB1/CCNB1/CCNL1 5 GO:0061980 regulatory RNA binding 2/221 46/18367 0.105785096859695 0.456757790705226 HNRNPA1/HNRNPA2B1 2 GO:0140677 molecular function activator activity 4/221 150/18367 0.107523248812759 0.456757790705226 ARF1/DNAJA1/AHSA1/AZIN1 4 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 2/221 47/18367 0.109646861451238 0.456757790705226 DUSP5/DUSP9 2 GO:0005031 tumor necrosis factor-activated receptor activity 1/221 10/18367 0.114040555778413 0.456757790705226 TNFRSF1A 1 GO:0005522 profilin binding 1/221 10/18367 0.114040555778413 0.456757790705226 ACTG1 1 GO:0008239 dipeptidyl-peptidase activity 1/221 10/18367 0.114040555778413 0.456757790705226 DPP7 1 GO:0008641 ubiquitin-like modifier activating enzyme activity 1/221 10/18367 0.114040555778413 0.456757790705226 UBA5 1 GO:0031720 haptoglobin binding 1/221 10/18367 0.114040555778413 0.456757790705226 HBG1 1 GO:0045294 alpha-catenin binding 1/221 10/18367 0.114040555778413 0.456757790705226 PKP3 1 GO:0097027 ubiquitin-protein transferase activator activity 1/221 10/18367 0.114040555778413 0.456757790705226 CDC20 1 GO:0015485 cholesterol binding 2/221 50/18367 0.12144715094925 0.456757790705226 CD81/CAV1 2 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 2/221 50/18367 0.12144715094925 0.456757790705226 CCNB1/CCNL1 2 GO:0000774 adenyl-nucleotide exchange factor activity 1/221 11/18367 0.124706625243629 0.456757790705226 HSPH1 1 GO:0008199 ferric iron binding 1/221 11/18367 0.124706625243629 0.456757790705226 FTL 1 GO:0016832 aldehyde-lyase activity 1/221 11/18367 0.124706625243629 0.456757790705226 ALDOA 1 GO:0032052 bile acid binding 1/221 11/18367 0.124706625243629 0.456757790705226 PYGL 1 GO:0043522 leucine zipper domain binding 1/221 11/18367 0.124706625243629 0.456757790705226 ATF4 1 GO:0051400 BH domain binding 1/221 11/18367 0.124706625243629 0.456757790705226 MCL1 1 GO:0070513 death domain binding 1/221 11/18367 0.124706625243629 0.456757790705226 MCL1 1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1/221 11/18367 0.124706625243629 0.456757790705226 DSP 1 GO:0097493 structural molecule activity conferring elasticity 1/221 11/18367 0.124706625243629 0.456757790705226 FBN1 1 GO:1901474 azole transmembrane transporter activity 1/221 11/18367 0.124706625243629 0.456757790705226 SLC28A2 1 GO:1901612 cardiolipin binding 1/221 11/18367 0.124706625243629 0.456757790705226 MME 1 GO:1990226 histone methyltransferase binding 1/221 11/18367 0.124706625243629 0.456757790705226 HSP90AB1 1 GO:1990459 transferrin receptor binding 1/221 11/18367 0.124706625243629 0.456757790705226 CD81 1 GO:0003743 translation initiation factor activity 2/221 51/18367 0.125447562235942 0.456757790705226 EIF4A1/EIF3A 2 GO:1990782 protein tyrosine kinase binding 3/221 105/18367 0.133047151260128 0.480119252735667 HSP90AA1/EIF3A/CRKL 3 GO:0003964 RNA-directed DNA polymerase activity 1/221 12/18367 0.13524485992554 0.480119252735667 PTGES3 1 GO:0030955 potassium ion binding 1/221 12/18367 0.13524485992554 0.480119252735667 PKM 1 GO:0003712 transcription coregulator activity 9/221 489/18367 0.136872466623054 0.481782527669803 HSPA1A/NPM1/RBFOX2/PAGE4/MED10/TCERG1/NUCKS1/ARID3A/HDGF 9 GO:0005035 death receptor activity 1/221 13/18367 0.14565678506618 0.481782527669803 TNFRSF1A 1 GO:0031386 protein tag 1/221 13/18367 0.14565678506618 0.481782527669803 UBA52 1 GO:0031994 insulin-like growth factor I binding 1/221 13/18367 0.14565678506618 0.481782527669803 IGFBP3 1 GO:0034236 protein kinase A catalytic subunit binding 1/221 13/18367 0.14565678506618 0.481782527669803 EZR 1 GO:0052650 NADP-retinol dehydrogenase activity 1/221 13/18367 0.14565678506618 0.481782527669803 RDH13 1 GO:0060590 ATPase regulator activity 1/221 13/18367 0.14565678506618 0.481782527669803 HSPH1 1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1/221 13/18367 0.14565678506618 0.481782527669803 CCNB1 1 GO:0004869 cysteine-type endopeptidase inhibitor activity 2/221 56/18367 0.145891892181701 0.481782527669803 SERPINB9/PTTG1 2 GO:0030674 protein-macromolecule adaptor activity 6/221 296/18367 0.14784483873692 0.484476163860985 CAV1/SUN2/KLF4/ICE1/CRKL/SYNE1 6 GO:0005344 oxygen carrier activity 1/221 14/18367 0.155943907791492 0.492089664586487 HBG1 1 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity 1/221 14/18367 0.155943907791492 0.492089664586487 B3GNT2 1 GO:0043023 ribosomal large subunit binding 1/221 14/18367 0.155943907791492 0.492089664586487 NPM1 1 GO:0044548 S100 protein binding 1/221 14/18367 0.155943907791492 0.492089664586487 EZR 1 GO:0140666 annealing activity 1/221 14/18367 0.155943907791492 0.492089664586487 ANXA1 1 GO:0004721 phosphoprotein phosphatase activity 4/221 174/18367 0.158289988379697 0.492751798245019 UBASH3B/DUSP5/PTPRG/DUSP9 4 GO:0036002 pre-mRNA binding 2/221 59/18367 0.158467127604619 0.492751798245019 HNRNPA1/SRSF6 2 GO:0003779 actin binding 8/221 440/18367 0.162219918122313 0.498644235190641 FLNB/MICAL3/EGFR/EZR/ALDOA/PDLIM2/TMSB10/SYNE1 8 GO:0032934 sterol binding 2/221 60/18367 0.162703165942486 0.498644235190641 CD81/CAV1 2 GO:0051371 muscle alpha-actinin binding 1/221 15/18367 0.166107717325524 0.501857358728178 PDLIM2 1 GO:1901611 phosphatidylglycerol binding 1/221 15/18367 0.166107717325524 0.501857358728178 MME 1 GO:1990841 promoter-specific chromatin binding 2/221 62/18367 0.171234941323516 0.507025445243903 ISL1/KLF4 2 GO:0008191 metalloendopeptidase inhibitor activity 1/221 16/18367 0.176149685202107 0.507025445243903 TIMP3 1 GO:0016004 phospholipase activator activity 1/221 16/18367 0.176149685202107 0.507025445243903 ARF1 1 GO:0016208 AMP binding 1/221 16/18367 0.176149685202107 0.507025445243903 PYGL 1 GO:0017070 U6 snRNA binding 1/221 16/18367 0.176149685202107 0.507025445243903 EIF5A 1 GO:0035173 histone kinase activity 1/221 16/18367 0.176149685202107 0.507025445243903 CHEK1 1 GO:0035497 cAMP response element binding 1/221 16/18367 0.176149685202107 0.507025445243903 JUN 1 GO:0000400 four-way junction DNA binding 1/221 17/18367 0.186071265474046 0.51025961725982 HMGB3 1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 1/221 17/18367 0.186071265474046 0.51025961725982 PTPRG 1 GO:0019198 transmembrane receptor protein phosphatase activity 1/221 17/18367 0.186071265474046 0.51025961725982 PTPRG 1 GO:0030275 LRR domain binding 1/221 17/18367 0.186071265474046 0.51025961725982 ATF4 1 GO:0031420 alkali metal ion binding 1/221 17/18367 0.186071265474046 0.51025961725982 PKM 1 GO:0043024 ribosomal small subunit binding 1/221 17/18367 0.186071265474046 0.51025961725982 NPM1 1 GO:0048531 beta-1,3-galactosyltransferase activity 1/221 17/18367 0.186071265474046 0.51025961725982 B3GNT2 1 GO:0043022 ribosome binding 2/221 66/18367 0.188507461672659 0.51025961725982 EIF5A/ETF1 2 GO:0003714 transcription corepressor activity 4/221 187/18367 0.18888056257855 0.51025961725982 HSPA1A/RBFOX2/TCERG1/HDGF 4 GO:0009055 electron transfer activity 3/221 126/18367 0.194023063704759 0.51025961725982 COX4I1/ETFB/UQCR11 3 GO:0004708 MAP kinase kinase activity 1/221 18/18367 0.195873894919835 0.51025961725982 MAPKAPK5 1 GO:0008301 DNA binding, bending 1/221 18/18367 0.195873894919835 0.51025961725982 HMGB3 1 GO:0060229 lipase activator activity 1/221 18/18367 0.195873894919835 0.51025961725982 ARF1 1 GO:0000339 RNA cap binding 1/221 19/18367 0.205558993247957 0.51025961725982 EIF4A1 1 GO:0003746 translation elongation factor activity 1/221 19/18367 0.205558993247957 0.51025961725982 EIF5A 1 GO:0004129 cytochrome-c oxidase activity 1/221 19/18367 0.205558993247957 0.51025961725982 COX4I1 1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 1/221 19/18367 0.205558993247957 0.51025961725982 GALNT11 1 GO:0005326 neurotransmitter transmembrane transporter activity 1/221 19/18367 0.205558993247957 0.51025961725982 SLC28A2 1 GO:0035613 RNA stem-loop binding 1/221 19/18367 0.205558993247957 0.51025961725982 DAZAP1 1 GO:0017124 SH3 domain binding 3/221 130/18367 0.206345477484307 0.51025961725982 PTTG1/BCAR1/ERRFI1 3 GO:0033218 amide binding 7/221 400/18367 0.208129330582842 0.51025961725982 SLC40A1/CD74/HSP90AB1/ITM2B/PPIL1/MME/KPNA2 7 GO:0031491 nucleosome binding 2/221 71/18367 0.210407537122992 0.51025961725982 ACTB/MBD3 2 GO:0016758 hexosyltransferase activity 4/221 197/18367 0.213591838977163 0.51025961725982 GALNT11/PYGL/B3GNT2/COLGALT1 4 GO:0003678 DNA helicase activity 2/221 72/18367 0.214819457518911 0.51025961725982 ANXA1/CHD2 2 GO:0016018 cyclosporin A binding 1/221 20/18367 0.215127963298764 0.51025961725982 PPIL1 1 GO:0016675 oxidoreductase activity, acting on a heme group of donors 1/221 20/18367 0.215127963298764 0.51025961725982 COX4I1 1 GO:0030506 ankyrin binding 1/221 20/18367 0.215127963298764 0.51025961725982 NRCAM 1 GO:0035014 phosphatidylinositol 3-kinase regulator activity 1/221 20/18367 0.215127963298764 0.51025961725982 KLF4 1 GO:0042288 MHC class I protein binding 1/221 20/18367 0.215127963298764 0.51025961725982 TUBB4B 1 GO:0061608 nuclear import signal receptor activity 1/221 20/18367 0.215127963298764 0.51025961725982 KPNA2 1 GO:0015370 solute:sodium symporter activity 2/221 73/18367 0.219239960974806 0.51025961725982 SLC6A8/SLC28A2 2 GO:0106306 protein serine phosphatase activity 2/221 73/18367 0.219239960974806 0.51025961725982 DUSP5/DUSP9 2 GO:0106307 protein threonine phosphatase activity 2/221 73/18367 0.219239960974806 0.51025961725982 DUSP5/DUSP9 2 GO:0140104 molecular carrier activity 2/221 73/18367 0.219239960974806 0.51025961725982 HBG1/KPNA2 2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 1/221 21/18367 0.224582191243985 0.51025961725982 LPCAT1 1 GO:0005243 gap junction channel activity 1/221 21/18367 0.224582191243985 0.51025961725982 GJA5 1 GO:0019003 GDP binding 2/221 75/18367 0.228103373419621 0.51025961725982 ARF1/RHOB 2 GO:0030246 carbohydrate binding 5/221 271/18367 0.228461193950773 0.51025961725982 GALNT11/SLC2A3/UGP2/PYGL/ALDOA 5 GO:0016887 ATP hydrolysis activity 5/221 272/18367 0.230659053868848 0.51025961725982 HSPA1A/HSPA1B/EIF4A1/HSP90AA1/CHD2 5 GO:0004602 glutathione peroxidase activity 1/221 22/18367 0.233923046783889 0.51025961725982 GPX3 1 GO:0005355 glucose transmembrane transporter activity 1/221 22/18367 0.233923046783889 0.51025961725982 SLC2A3 1 GO:0008106 alcohol dehydrogenase (NADP+) activity 1/221 22/18367 0.233923046783889 0.51025961725982 RDH13 1 GO:0008320 protein transmembrane transporter activity 1/221 22/18367 0.233923046783889 0.51025961725982 MCL1 1 GO:0015149 hexose transmembrane transporter activity 1/221 22/18367 0.233923046783889 0.51025961725982 SLC2A3 1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 1/221 22/18367 0.233923046783889 0.51025961725982 SERPINB9 1 GO:0072349 modified amino acid transmembrane transporter activity 1/221 22/18367 0.233923046783889 0.51025961725982 SLC6A8 1 GO:0019955 cytokine binding 3/221 139/18367 0.234670047812189 0.51025961725982 CD74/TNFRSF1A/CSF3R 3 GO:0001221 transcription coregulator binding 2/221 78/18367 0.241442454189559 0.51025961725982 KLF4/HDGF 2 GO:0030971 receptor tyrosine kinase binding 2/221 78/18367 0.241442454189559 0.51025961725982 EIF3A/CRKL 2 GO:0008143 poly(A) binding 1/221 23/18367 0.243151883342121 0.51025961725982 PABPC4 1 GO:0009931 calcium-dependent protein serine/threonine kinase activity 1/221 23/18367 0.243151883342121 0.51025961725982 MAPKAPK5 1 GO:0042171 lysophosphatidic acid acyltransferase activity 1/221 23/18367 0.243151883342121 0.51025961725982 LPCAT1 1 GO:0050750 low-density lipoprotein particle receptor binding 1/221 23/18367 0.243151883342121 0.51025961725982 DNAJA1 1 GO:0070412 R-SMAD binding 1/221 23/18367 0.243151883342121 0.51025961725982 JUN 1 GO:0071617 lysophospholipid acyltransferase activity 1/221 23/18367 0.243151883342121 0.51025961725982 LPCAT1 1 GO:0008194 UDP-glycosyltransferase activity 3/221 143/18367 0.247476742489613 0.516668443740445 GALNT11/B3GNT2/COLGALT1 3 GO:0005178 integrin binding 3/221 144/18367 0.250695674505062 0.516668443740445 CD81/FBN1/EGFR 3 GO:0010857 calcium-dependent protein kinase activity 1/221 24/18367 0.252270038258245 0.516668443740445 MAPKAPK5 1 GO:0015145 monosaccharide transmembrane transporter activity 1/221 24/18367 0.252270038258245 0.516668443740445 SLC2A3 1 GO:0043274 phospholipase binding 1/221 24/18367 0.252270038258245 0.516668443740445 SRSF3 1 GO:0005112 Notch binding 1/221 25/18367 0.261278832978026 0.524384734435624 GALNT11 1 GO:0008327 methyl-CpG binding 1/221 25/18367 0.261278832978026 0.524384734435624 MBD3 1 GO:0034237 protein kinase A regulatory subunit binding 1/221 25/18367 0.261278832978026 0.524384734435624 EZR 1 GO:0051019 mitogen-activated protein kinase binding 1/221 25/18367 0.261278832978026 0.524384734435624 MAPKAPK5 1 GO:0051015 actin filament binding 4/221 217/18367 0.265358801960038 0.524384734435624 FLNB/EGFR/EZR/SYNE1 4 GO:0001540 amyloid-beta binding 2/221 84/18367 0.268204602205684 0.524384734435624 CD74/ITM2B 2 GO:0030165 PDZ domain binding 2/221 84/18367 0.268204602205684 0.524384734435624 CADM1/LIN7C 2 GO:0008198 ferrous iron binding 1/221 26/18367 0.270179573241457 0.524384734435624 FTL 1 GO:0051020 GTPase binding 5/221 291/18367 0.27347215010023 0.524384734435624 MICAL3/CAV1/YBX3/HSP90AA1/ERRFI1 5 GO:0042562 hormone binding 2/221 86/18367 0.277129803371067 0.524384734435624 SLC40A1/EGFR 2 GO:0004683 calmodulin-dependent protein kinase activity 1/221 27/18367 0.278973549268589 0.524384734435624 MAPKAPK5 1 GO:0004709 MAP kinase kinase kinase activity 1/221 27/18367 0.278973549268589 0.524384734435624 EGFR 1 GO:0008139 nuclear localization sequence binding 1/221 27/18367 0.278973549268589 0.524384734435624 KPNA2 1 GO:0022884 macromolecule transmembrane transporter activity 1/221 27/18367 0.278973549268589 0.524384734435624 MCL1 1 GO:0051119 sugar transmembrane transporter activity 1/221 27/18367 0.278973549268589 0.524384734435624 SLC2A3 1 GO:0051393 alpha-actinin binding 1/221 27/18367 0.278973549268589 0.524384734435624 PDLIM2 1 GO:0051959 dynein light intermediate chain binding 1/221 27/18367 0.278973549268589 0.524384734435624 DYNLL1 1 GO:0005253 anion channel activity 2/221 87/18367 0.281590332076215 0.524384734435624 LRRC8D/FXYD3 2 GO:0060090 molecular adaptor activity 6/221 369/18367 0.285271484569417 0.524384734435624 CAV1/SUN2/KLF4/ICE1/CRKL/SYNE1 6 GO:0048306 calcium-dependent protein binding 2/221 88/18367 0.286048667515951 0.524384734435624 ANXA1/ANXA4 2 GO:0051219 phosphoprotein binding 2/221 88/18367 0.286048667515951 0.524384734435624 UBASH3B/CRKL 2 GO:0001968 fibronectin binding 1/221 28/18367 0.287662035943161 0.524384734435624 IGFBP3 1 GO:0003785 actin monomer binding 1/221 28/18367 0.287662035943161 0.524384734435624 TMSB10 1 GO:0046875 ephrin receptor binding 1/221 28/18367 0.287662035943161 0.524384734435624 EFNB1 1 GO:0070325 lipoprotein particle receptor binding 1/221 28/18367 0.287662035943161 0.524384734435624 DNAJA1 1 GO:0004386 helicase activity 3/221 156/18367 0.289728264158756 0.524384734435624 ANXA1/EIF4A1/CHD2 3 GO:0019888 protein phosphatase regulator activity 2/221 89/18367 0.290504219077012 0.524384734435624 IGFBP3/PPP1R15A 2 GO:0043178 alcohol binding 2/221 89/18367 0.290504219077012 0.524384734435624 CD81/CAV1 2 GO:0004033 aldo-keto reductase (NADP) activity 1/221 29/18367 0.296246292994067 0.525837170064469 RDH13 1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 1/221 29/18367 0.296246292994067 0.525837170064469 CDK11B 1 GO:0005520 insulin-like growth factor binding 1/221 29/18367 0.296246292994067 0.525837170064469 IGFBP3 1 GO:0097472 cyclin-dependent protein kinase activity 1/221 29/18367 0.296246292994067 0.525837170064469 CDK11B 1 GO:0015631 tubulin binding 6/221 375/18367 0.297743318765166 0.526220983160239 CCSAP/CAPN6/SUN2/EZR/ALDOA/HSPH1 6 GO:0016407 acetyltransferase activity 2/221 91/18367 0.29940467986065 0.526220983160239 SAT1/LPCAT1 2 GO:0061134 peptidase regulator activity 4/221 230/18367 0.300168307295629 0.526220983160239 SERPINB9/TIMP3/CAV1/PTTG1 4 GO:0005525 GTP binding 6/221 377/18367 0.30192477743337 0.527130963879572 TUBA1C/GNL3/HSP90AB1/ARF1/RHOB/TUBB4B 6 GO:0022829 wide pore channel activity 1/221 30/18367 0.304727565174693 0.529852827609874 GJA5 1 GO:0008157 protein phosphatase 1 binding 1/221 31/18367 0.313107082440134 0.533534468477987 PPP1R15A 1 GO:0016411 acylglycerol O-acyltransferase activity 1/221 31/18367 0.313107082440134 0.533534468477987 LPCAT1 1 GO:0090482 vitamin transmembrane transporter activity 1/221 31/18367 0.313107082440134 0.533534468477987 SLC2A3 1 GO:0140142 nucleocytoplasmic carrier activity 1/221 31/18367 0.313107082440134 0.533534468477987 KPNA2 1 GO:0140318 protein transporter activity 1/221 31/18367 0.313107082440134 0.533534468477987 MCL1 1 GO:0001222 transcription corepressor binding 1/221 32/18367 0.321386060122329 0.543295482587746 HDGF 1 GO:0140658 ATP-dependent chromatin remodeler activity 1/221 32/18367 0.321386060122329 0.543295482587746 CHD2 1 GO:0004896 cytokine receptor activity 2/221 97/18367 0.325982173443527 0.548886979790286 CD74/CSF3R 2 GO:0008200 ion channel inhibitor activity 1/221 33/18367 0.329565699103128 0.54978692258054 CAV1 1 GO:0031369 translation initiation factor binding 1/221 33/18367 0.329565699103128 0.54978692258054 RPS24 1 GO:0004722 protein serine/threonine phosphatase activity 2/221 98/18367 0.330388385400512 0.54978692258054 DUSP5/DUSP9 2 GO:0008376 acetylgalactosaminyltransferase activity 1/221 34/18367 0.337647185985326 0.55535791980598 GALNT11 1 GO:0016248 channel inhibitor activity 1/221 34/18367 0.337647185985326 0.55535791980598 CAV1 1 GO:0045505 dynein intermediate chain binding 1/221 34/18367 0.337647185985326 0.55535791980598 DYNLL1 1 GO:0005496 steroid binding 2/221 100/18367 0.33917654590891 0.555727725219983 CD81/CAV1 2 GO:0030295 protein kinase activator activity 2/221 101/18367 0.343557614739444 0.56074921026438 RPLP1/CCNB1 2 GO:0019001 guanyl nucleotide binding 6/221 398/18367 0.346392006840713 0.56107602628952 TUBA1C/GNL3/HSP90AB1/ARF1/RHOB/TUBB4B 6 GO:0032561 guanyl ribonucleotide binding 6/221 398/18367 0.346392006840713 0.56107602628952 TUBA1C/GNL3/HSP90AB1/ARF1/RHOB/TUBB4B 6 GO:0031490 chromatin DNA binding 2/221 103/18367 0.352291617267784 0.564043751532914 ACTB/MBD3 2 GO:0000217 DNA secondary structure binding 1/221 36/18367 0.353520379481897 0.564043751532914 HMGB3 1 GO:0034061 DNA polymerase activity 1/221 36/18367 0.353520379481897 0.564043751532914 PTGES3 1 GO:0042805 actinin binding 1/221 36/18367 0.353520379481897 0.564043751532914 PDLIM2 1 GO:0015294 solute:cation symporter activity 2/221 104/18367 0.356643739963034 0.566903855314375 SLC6A8/SLC28A2 2 GO:0043531 ADP binding 1/221 37/18367 0.36131438941777 0.570073814414704 CHORDC1 1 GO:0071949 FAD binding 1/221 37/18367 0.36131438941777 0.570073814414704 MICAL3 1 GO:0004866 endopeptidase inhibitor activity 3/221 180/18367 0.368584400984396 0.572599701121721 SERPINB9/TIMP3/PTTG1 3 GO:0003755 peptidyl-prolyl cis-trans isomerase activity 1/221 38/18367 0.369014854226209 0.572599701121721 PPIL1 1 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1/221 38/18367 0.369014854226209 0.572599701121721 TCERG1 1 GO:0019208 phosphatase regulator activity 2/221 107/18367 0.369635957296885 0.572599701121721 IGFBP3/PPP1R15A 2 GO:0019209 kinase activator activity 2/221 107/18367 0.369635957296885 0.572599701121721 RPLP1/CCNB1 2 GO:0019825 oxygen binding 1/221 39/18367 0.376622891610464 0.57718738320317 HBG1 1 GO:0031267 small GTPase binding 4/221 259/18367 0.37914741563036 0.57718738320317 MICAL3/CAV1/YBX3/ERRFI1 4 GO:0008047 enzyme activator activity 2/221 110/18367 0.38252433215128 0.57718738320317 ARF1/AZIN1 2 GO:0015144 carbohydrate transmembrane transporter activity 1/221 40/18367 0.384139605979412 0.57718738320317 SLC2A3 1 GO:0017080 sodium channel regulator activity 1/221 40/18367 0.384139605979412 0.57718738320317 FXYD3 1 GO:0043014 alpha-tubulin binding 1/221 40/18367 0.384139605979412 0.57718738320317 HSPH1 1 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1/221 40/18367 0.384139605979412 0.57718738320317 SERPINB9 1 GO:0004222 metalloendopeptidase activity 2/221 111/18367 0.386795783102155 0.57718738320317 ADAMTS6/MME 2 GO:0008094 ATP-dependent activity, acting on DNA 2/221 111/18367 0.386795783102155 0.57718738320317 ANXA1/CHD2 2 GO:0003713 transcription coactivator activity 4/221 262/18367 0.387319782911226 0.57718738320317 NPM1/PAGE4/TCERG1/NUCKS1 4 GO:0030414 peptidase inhibitor activity 3/221 187/18367 0.391406777910984 0.57718738320317 SERPINB9/TIMP3/PTTG1 3 GO:0016859 cis-trans isomerase activity 1/221 41/18367 0.391566088604967 0.57718738320317 PPIL1 1 GO:0016877 ligase activity, forming carbon-sulfur bonds 1/221 41/18367 0.391566088604967 0.57718738320317 UBA5 1 GO:0030331 estrogen receptor binding 1/221 41/18367 0.391566088604967 0.57718738320317 ISL1 1 GO:0008022 protein C-terminus binding 3/221 189/18367 0.397891993202057 0.57997561765622 STIP1/EZR/CDC20 3 GO:0001046 core promoter sequence-specific DNA binding 1/221 42/18367 0.398903417777635 0.57997561765622 NPM1 1 GO:0008307 structural constituent of muscle 1/221 42/18367 0.398903417777635 0.57997561765622 KRT19 1 GO:0019894 kinesin binding 1/221 42/18367 0.398903417777635 0.57997561765622 ACTB 1 GO:0008237 metallopeptidase activity 3/221 190/18367 0.401127761722646 0.581225940455263 TFRC/ADAMTS6/MME 3 GO:0004180 carboxypeptidase activity 1/221 43/18367 0.406152658960234 0.582089117498649 BLMH 1 GO:0016504 peptidase activator activity 1/221 43/18367 0.406152658960234 0.582089117498649 CAV1 1 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 1/221 43/18367 0.406152658960234 0.582089117498649 MICAL3 1 GO:0016757 glycosyltransferase activity 4/221 270/18367 0.409039191666795 0.582089117498649 GALNT11/PYGL/B3GNT2/COLGALT1 4 GO:0008017 microtubule binding 4/221 271/18367 0.411744480022091 0.582089117498649 CCSAP/CAPN6/SUN2/EZR 4 GO:0001784 phosphotyrosine residue binding 1/221 44/18367 0.413314864939813 0.582089117498649 CRKL 1 GO:0004712 protein serine/threonine/tyrosine kinase activity 1/221 44/18367 0.413314864939813 0.582089117498649 MAPKAPK5 1 GO:0008375 acetylglucosaminyltransferase activity 1/221 44/18367 0.413314864939813 0.582089117498649 B3GNT2 1 GO:0061135 endopeptidase regulator activity 3/221 194/18367 0.414021132868758 0.582089117498649 SERPINB9/TIMP3/PTTG1 3 GO:0016829 lyase activity 3/221 196/18367 0.420435616597875 0.585372873428521 AMD1/ALDOA/AZIN1 3 GO:0019902 phosphatase binding 3/221 196/18367 0.420435616597875 0.585372873428521 PPP1R15A/TPRN/EGFR 3 GO:0004197 cysteine-type endopeptidase activity 2/221 119/18367 0.420479106265557 0.585372873428521 BLMH/LGMN 2 GO:0016791 phosphatase activity 4/221 275/18367 0.42253932531177 0.58632492697985 UBASH3B/DUSP5/PTPRG/DUSP9 4 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 2/221 124/18367 0.441049567603381 0.610023103243638 LDHA/RDH13 2 GO:0043539 protein serine/threonine kinase activator activity 1/221 49/18367 0.447856345801913 0.617433020425938 CCNB1 1 GO:0005048 signal sequence binding 1/221 50/18367 0.454517757941763 0.622587025347881 KPNA2 1 GO:0015932 nucleobase-containing compound transmembrane transporter activity 1/221 50/18367 0.454517757941763 0.622587025347881 SLC28A2 1 GO:0016860 intramolecular oxidoreductase activity 1/221 51/18367 0.46109916185588 0.627566271407683 PTGES3 1 GO:0051018 protein kinase A binding 1/221 51/18367 0.46109916185588 0.627566271407683 EZR 1 GO:0017046 peptide hormone binding 1/221 52/18367 0.467601514183345 0.634389315420716 SLC40A1 1 GO:0016779 nucleotidyltransferase activity 2/221 132/18367 0.473109868537263 0.637018844906021 UGP2/PTGES3 2 GO:0017069 snRNA binding 1/221 53/18367 0.474025760176546 0.637018844906021 EIF5A 1 GO:1901505 carbohydrate derivative transmembrane transporter activity 1/221 53/18367 0.474025760176546 0.637018844906021 SLC28A2 1 GO:0044325 transmembrane transporter binding 2/221 133/18367 0.477039762346295 0.639053266539377 CAV1/HSP90AB1 2 GO:0008374 O-acyltransferase activity 1/221 54/18367 0.480372833836095 0.639496335044302 LPCAT1 1 GO:0015459 potassium channel regulator activity 1/221 54/18367 0.480372833836095 0.639496335044302 CAV1 1 GO:0002020 protease binding 2/221 135/18367 0.484846050421324 0.64182723940189 SERPINB9/TIMP3 2 GO:0005080 protein kinase C binding 1/221 55/18367 0.486643658044156 0.64182723940189 DSP 1 GO:0030170 pyridoxal phosphate binding 1/221 55/18367 0.486643658044156 0.64182723940189 PYGL 1 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 2/221 136/18367 0.488722166120012 0.642047326117987 LDHA/RDH13 2 GO:0045309 protein phosphorylated amino acid binding 1/221 56/18367 0.492839144696201 0.642047326117987 CRKL 1 GO:0051287 NAD binding 1/221 56/18367 0.492839144696201 0.642047326117987 LDHA 1 GO:0070279 vitamin B6 binding 1/221 56/18367 0.492839144696201 0.642047326117987 PYGL 1 GO:0004674 protein serine/threonine kinase activity 5/221 386/18367 0.497078152564155 0.645595405464421 EGFR/CHEK1/CDK11B/MAPKAPK5/CSNK1E 5 GO:0099106 ion channel regulator activity 2/221 139/18367 0.500240851003052 0.647728275158967 CAV1/FXYD3 2 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 1/221 58/18367 0.505007698760336 0.651919029308797 SMS 1 GO:0019838 growth factor binding 2/221 141/18367 0.507827410810184 0.653578480378061 IGFBP3/EGFR 2 GO:0001786 phosphatidylserine binding 1/221 60/18367 0.51688557636781 0.658881618751758 MME 1 GO:0015293 symporter activity 2/221 144/18367 0.519066290464137 0.658881618751758 SLC6A8/SLC28A2 2 GO:0140375 immune receptor activity 2/221 144/18367 0.519066290464137 0.658881618751758 CD74/CSF3R 2 GO:0140097 catalytic activity, acting on DNA 3/221 229/18367 0.522092118991244 0.658881618751758 ANXA1/PTGES3/CHD2 3 GO:0005507 copper ion binding 1/221 61/18367 0.522717678166178 0.658881618751758 F5 1 GO:0043621 protein self-association 1/221 61/18367 0.522717678166178 0.658881618751758 TMEM43 1 GO:0016247 channel regulator activity 2/221 145/18367 0.522774617695057 0.658881618751758 CAV1/FXYD3 2 GO:0008509 anion transmembrane transporter activity 4/221 314/18367 0.524377824516103 0.658952664436165 SLC6A8/LRRC8D/SLC2A3/FXYD3 4 GO:0019903 protein phosphatase binding 2/221 150/18367 0.541027872147284 0.677876098631596 PPP1R15A/EGFR 2 GO:0015081 sodium ion transmembrane transporter activity 2/221 152/18367 0.548193322722359 0.682837296724342 SLC6A8/SLC28A2 2 GO:0015103 inorganic anion transmembrane transporter activity 2/221 152/18367 0.548193322722359 0.682837296724342 LRRC8D/FXYD3 2 GO:0002039 p53 binding 1/221 66/18367 0.550843463265783 0.68413794563039 MAPKAPK5 1 GO:0008080 N-acetyltransferase activity 1/221 68/18367 0.561626144890014 0.695502144544029 SAT1 1 GO:0042393 histone binding 3/221 244/18367 0.56501964509506 0.69767643133477 NPM1/MORC4/CHD2 3 GO:0016853 isomerase activity 2/221 158/18367 0.569218357275239 0.700829538148127 PTGES3/PPIL1 2 GO:0004860 protein kinase inhibitor activity 1/221 70/18367 0.572151115193514 0.702410302802412 NPM1 1 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 1/221 71/18367 0.577318880594521 0.702982251586309 ASAH1 1 GO:0003924 GTPase activity 4/221 337/18367 0.580291814576649 0.702982251586309 TUBA1C/ARF1/RHOB/TUBB4B 4 GO:0000049 tRNA binding 1/221 72/18367 0.582424506271643 0.702982251586309 RPL35A 1 GO:0008235 metalloexopeptidase activity 1/221 72/18367 0.582424506271643 0.702982251586309 TFRC 1 GO:0015453 oxidoreduction-driven active transmembrane transporter activity 1/221 72/18367 0.582424506271643 0.702982251586309 COX4I1 1 GO:0033293 monocarboxylic acid binding 1/221 73/18367 0.587468736067432 0.702982251586309 PYGL 1 GO:0035064 methylated histone binding 1/221 73/18367 0.587468736067432 0.702982251586309 MORC4 1 GO:0070063 RNA polymerase binding 1/221 73/18367 0.587468736067432 0.702982251586309 TCERG1 1 GO:0140034 methylation-dependent protein binding 1/221 73/18367 0.587468736067432 0.702982251586309 MORC4 1 GO:0005254 chloride channel activity 1/221 74/18367 0.592452304960462 0.704985145008818 FXYD3 1 GO:0019210 kinase inhibitor activity 1/221 74/18367 0.592452304960462 0.704985145008818 NPM1 1 GO:0008201 heparin binding 2/221 166/18367 0.596142148229349 0.707399875057668 FBN1/HDGF 2 GO:0003724 RNA helicase activity 1/221 77/18367 0.60704626524845 0.716348224365207 EIF4A1 1 GO:0038024 cargo receptor activity 1/221 77/18367 0.60704626524845 0.716348224365207 TFRC 1 GO:0008186 ATP-dependent activity, acting on RNA 1/221 79/18367 0.61648535280053 0.723478678493184 EIF4A1 1 GO:0046332 SMAD binding 1/221 79/18367 0.61648535280053 0.723478678493184 JUN 1 GO:0035591 signaling adaptor activity 1/221 81/18367 0.625698706708254 0.730729546515824 CRKL 1 GO:0022853 active ion transmembrane transporter activity 3/221 267/18367 0.626094564502995 0.730729546515824 SLC6A8/COX4I1/SLC28A2 3 GO:0106310 protein serine kinase activity 4/221 360/18367 0.632291194568046 0.735945488759529 CHEK1/CDK11B/MAPKAPK5/CSNK1E 4 GO:0008013 beta-catenin binding 1/221 85/18367 0.643469583867856 0.744819328141566 KLF4 1 GO:0050660 flavin adenine dinucleotide binding 1/221 85/18367 0.643469583867856 0.744819328141566 MICAL3 1 GO:0042578 phosphoric ester hydrolase activity 4/221 366/18367 0.64516040395361 0.744819328141566 UBASH3B/DUSP5/PTPRG/DUSP9 4 GO:0008514 organic anion transmembrane transporter activity 2/221 185/18367 0.654990624775996 0.754124340958309 SLC6A8/SLC2A3 2 GO:0005543 phospholipid binding 5/221 466/18367 0.663517561416943 0.761882698554226 ANXA1/PXDC1/ANXA5/MME/ANXA4 5 GO:0008234 cysteine-type peptidase activity 2/221 190/18367 0.669298404480816 0.766454624486096 BLMH/LGMN 2 GO:0072341 modified amino acid binding 1/221 93/18367 0.676530640183644 0.772659658762017 MME 1 GO:0016410 N-acyltransferase activity 1/221 94/18367 0.680442576733902 0.775049566012412 SAT1 1 GO:0001664 G protein-coupled receptor binding 3/221 295/18367 0.69218527639337 0.786322473982868 HSPA1A/HSPA1B/DNAJA1 3 GO:0004867 serine-type endopeptidase inhibitor activity 1/221 98/18367 0.695624951975567 0.788128270057424 SERPINB9 1 GO:0005516 calmodulin binding 2/221 201/18367 0.699091182419716 0.789954492601589 EGFR/MAPKAPK5 2 GO:0004497 monooxygenase activity 1/221 102/18367 0.710089111902273 0.800259157858117 MICAL3 1 GO:0000287 magnesium ion binding 2/221 221/18367 0.747562849245299 0.840268532397091 PKM/ARF1 2 GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups 2/221 222/18367 0.74980166177359 0.840567126093551 SAT1/LPCAT1 2 GO:0046982 protein heterodimerization activity 3/221 328/18367 0.75837250079774 0.847944056010072 ATF4/CAV1/MCL1 3 GO:0004175 endopeptidase activity 4/221 430/18367 0.763619979356638 0.849352770772658 ADAMTS6/MME/BLMH/LGMN 4 GO:0046873 metal ion transmembrane transporter activity 4/221 430/18367 0.763619979356638 0.849352770772658 SLC6A8/SLC40A1/SLC25A37/SLC28A2 4 GO:0005539 glycosaminoglycan binding 2/221 230/18367 0.767106723763039 0.851009021674622 FBN1/HDGF 2 GO:0005179 hormone activity 1/221 122/18367 0.772766691371697 0.855061326037254 FBN1 1 GO:0004714 transmembrane receptor protein tyrosine kinase activity 1/221 124/18367 0.778238412330018 0.858884879928984 EGFR 1 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1/221 125/18367 0.780924884449465 0.859622741021892 ASAH1 1 GO:0015291 secondary active transmembrane transporter activity 2/221 240/18367 0.787273102257707 0.864377168973668 SLC6A8/SLC28A2 2 GO:0015078 proton transmembrane transporter activity 1/221 130/18367 0.793878969180856 0.869389308151785 COX4I1 1 GO:0016746 acyltransferase activity 2/221 250/18367 0.805893254486038 0.878224962680248 SAT1/LPCAT1 2 GO:0043177 organic acid binding 1/221 135/18367 0.80607032959619 0.878224962680248 HBG1 1 GO:0004713 protein tyrosine kinase activity 1/221 136/18367 0.808421056733051 0.878539209612958 EGFR 1 GO:0020037 heme binding 1/221 139/18367 0.815304394788576 0.883765069160136 HBG1 1 GO:0019199 transmembrane receptor protein kinase activity 1/221 143/18367 0.824100669866105 0.891032703966906 EGFR 1 GO:0016922 nuclear receptor binding 1/221 144/18367 0.826233777414371 0.891077440958283 ISL1 1 GO:1901681 sulfur compound binding 2/221 265/18367 0.831118178131331 0.894081676474614 FBN1/HDGF 2 GO:0019842 vitamin binding 1/221 148/18367 0.834511761433631 0.895369760412516 PYGL 1 GO:0046906 tetrapyrrole binding 1/221 149/18367 0.836519165831412 0.895369760412516 HBG1 1 GO:0005506 iron ion binding 1/221 151/18367 0.840461541991403 0.897334879419392 FTL 1 GO:0140030 modification-dependent protein binding 1/221 160/18367 0.857063104106745 0.912772205873684 MORC4 1 GO:0008083 growth factor activity 1/221 162/18367 0.860512128554426 0.914160016868293 HDGF 1 GO:0016874 ligase activity 1/221 165/18367 0.865530930580983 0.917204418973878 UBA5 1 GO:0022804 active transmembrane transporter activity 3/221 406/18367 0.869785475675958 0.91942583781131 SLC6A8/COX4I1/SLC28A2 3 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 1/221 170/18367 0.873499243879836 0.921066034388144 MICAL3 1 GO:0005201 extracellular matrix structural constituent 1/221 172/18367 0.876553336432595 0.922004250173545 FBN1 1 GO:0031406 carboxylic acid binding 1/221 176/18367 0.882443051246449 0.924709080943747 PYGL 1 GO:0061630 ubiquitin protein ligase activity 2/221 304/18367 0.883466187662219 0.924709080943747 MED10/RBBP6 2 GO:0015399 primary active transmembrane transporter activity 1/221 181/18367 0.889413303479312 0.928652125691635 COX4I1 1 GO:0061659 ubiquitin-like protein ligase activity 2/221 316/18367 0.896283562260615 0.933537402256778 MED10/RBBP6 2 GO:0008236 serine-type peptidase activity 1/221 191/18367 0.902143425664768 0.937349022763881 DPP7 1 GO:0017171 serine hydrolase activity 1/221 195/18367 0.906817013533203 0.939912524976021 DPP7 1 GO:0015267 channel activity 3/221 480/18367 0.930947445290993 0.960877730865288 LRRC8D/GJA5/FXYD3 3 GO:0022803 passive transmembrane transporter activity 3/221 481/18367 0.931555171003202 0.960877730865288 LRRC8D/GJA5/FXYD3 3 GO:0048018 receptor ligand activity 3/221 487/18367 0.935099794463317 0.962204136331819 FBN1/FAM3B/HDGF 3 GO:0030546 signaling receptor activator activity 3/221 495/18367 0.939563982524189 0.964468088085071 FBN1/FAM3B/HDGF 3 GO:0005125 cytokine activity 1/221 235/18367 0.942912169004576 0.96557832691334 FAM3B 1 GO:0035091 phosphatidylinositol binding 1/221 271/18367 0.963303422999291 0.984094144358988 PXDC1 1 GO:0005216 ion channel activity 2/221 432/18367 0.967859411857249 0.98436700472773 LRRC8D/FXYD3 2 GO:0004842 ubiquitin-protein transferase activity 2/221 433/18367 0.968191960049105 0.98436700472773 MED10/RBBP6 2 GO:0019787 ubiquitin-like protein transferase activity 2/221 458/18367 0.975509309391927 0.984475339758577 MED10/RBBP6 2 GO:0005096 GTPase activator activity 2/221 462/18367 0.976518314328359 0.984475339758577 JUN/ERRFI1 2 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 1/221 310/18367 0.977286690216067 0.984475339758577 JUN 1 GO:0001217 DNA-binding transcription repressor activity 1/221 313/18367 0.978110536013205 0.984475339758577 JUN 1 GO:0030695 GTPase regulator activity 2/221 488/18367 0.982164364782617 0.984475339758577 JUN/ERRFI1 2 GO:0060589 nucleoside-triphosphatase regulator activity 2/221 488/18367 0.982164364782617 0.984475339758577 JUN/ERRFI1 2 GO:0140098 catalytic activity, acting on RNA 1/221 386/18367 0.99110859302933 0.99110859302933 EIF4A1 1