ID Description GeneRatio BgRatio pvalue p.adjust geneID geneName Count hsa03010 Ribosome 23/127 91/5868 4.20194724651642e-19 5.12637564075003e-17 6170/6235/6234/2197/6164/6232/6158/6209/6206/6233/25873/6141/6136/6210/6176/6208/6181/6228/6134/6168/6165/6171/6229 RPL39/RPS29/RPS28/FAU/RPL34/RPS27/RPL28/RPS15/RPS12/RPS27A/RPL36/RPL18/RPL12/RPS15A/RPLP1/RPS14/RPLP2/RPS23/RPL10/RPL37A/RPL35A/RPL41/RPS24 23 hsa04512 ECM-receptor interaction 14/127 85/5868 2.48872315400281e-09 1.51812112394171e-07 2335/3915/3655/3912/1284/1605/6696/3911/3693/3685/961/3691/3688/1282 FN1/LAMC1/ITGA6/LAMB1/COL4A2/DAG1/SPP1/LAMA5/ITGB5/ITGAV/CD47/ITGB4/ITGB1/COL4A1 14 hsa04510 Focal adhesion 18/127 200/5868 2.21994132474742e-07 9.02776138730617e-06 2335/3915/3655/3912/1956/4233/2321/1284/6696/3911/3693/3480/3685/3691/3688/1282/1499/394 FN1/LAMC1/ITGA6/LAMB1/EGFR/MET/FLT1/COL4A2/SPP1/LAMA5/ITGB5/IGF1R/ITGAV/ITGB4/ITGB1/COL4A1/CTNNB1/ARHGAP5 18 hsa05222 Small cell lung cancer 10/127 85/5868 1.25144849748297e-05 0.000381691791732307 2335/3915/3655/3912/1284/3911/3685/3688/1021/1282 FN1/LAMC1/ITGA6/LAMB1/COL4A2/LAMA5/ITGAV/ITGB1/CDK6/COL4A1 10 hsa05200 Pathways in cancer 19/127 326/5868 6.34803930014038e-05 0.00154892158923425 2335/3915/3655/3912/1956/4233/1284/3911/1441/999/3480/3685/7184/3688/1021/6513/1282/1499/1857 FN1/LAMC1/ITGA6/LAMB1/EGFR/MET/COL4A2/LAMA5/CSF3R/CDH1/IGF1R/ITGAV/HSP90B1/ITGB1/CDK6/SLC2A1/COL4A1/CTNNB1/DVL3 19 hsa05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC) 8/127 74/5868 0.000175610198802865 0.0035707407089916 3655/1605/3693/3685/3691/3688/1824/1499 ITGA6/DAG1/ITGB5/ITGAV/ITGB4/ITGB1/DSC2/CTNNB1 8 hsa04145 Phagosome 11/127 153/5868 0.000435649933520897 0.00759275598422135 81035/821/3693/3685/4973/1514/7037/3688/811/8411/525 COLEC12/CANX/ITGB5/ITGAV/OLR1/CTSL/TFRC/ITGB1/CALR/EEA1/ATP6V1B1 11 hsa04141 Protein processing in endoplasmic reticulum 11/127 165/5868 0.000824766799713295 0.0125776936956278 6238/821/23193/7184/5034/6185/3998/811/201595/5589/9601 RRBP1/CANX/GANAB/HSP90B1/P4HB/RPN2/LMAN1/CALR/STT3B/PRKCSH/PDIA4 11 hsa05414 Dilated cardiomyopathy 7/127 90/5868 0.0031772140454641 0.0430689015051801 3655/1605/3693/3685/153/3691/3688 ITGA6/DAG1/ITGB5/ITGAV/ADRB1/ITGB4/ITGB1 7 hsa00510 N-Glycan biosynthesis 5/127 49/5868 0.00390466434519869 0.0446154539055534 23193/4124/6185/2683/201595 GANAB/MAN2A1/RPN2/B4GALT1/STT3B 5 hsa04142 Lysosome 8/127 121/5868 0.00449416947319217 0.0446154539055534 2720/2799/1514/5641/950/1075/5660/2760 GLB1/GNS/CTSL/LGMN/SCARB2/CTSC/PSAP/GM2A 8 hsa05144 Malaria 5/127 51/5868 0.0046476915684443 0.0446154539055534 3039/3040/4035/4233/3043 HBA1/HBA2/LRP1/MET/HBB 5 hsa04520 Adherens junction 6/127 73/5868 0.00475410574403438 0.0446154539055534 1956/4233/999/5792/3480/1499 EGFR/MET/CDH1/PTPRF/IGF1R/CTNNB1 6 hsa05410 Hypertrophic cardiomyopathy (HCM) 6/127 83/5868 0.00885019718531675 0.0771231469006174 3655/1605/3693/3685/3691/3688 ITGA6/DAG1/ITGB5/ITGAV/ITGB4/ITGB1 6 hsa05100 Bacterial invasion of epithelial cells 5/127 70/5868 0.0173085006397864 0.139582738468892 2335/4233/999/3688/1499 FN1/MET/CDH1/ITGB1/CTNNB1 5 hsa05218 Melanoma 5/127 71/5868 0.018305932913953 0.139582738468892 1956/4233/999/3480/1021 EGFR/MET/CDH1/IGF1R/CDK6 5 hsa04612 Antigen processing and presentation 5/127 76/5868 0.023862386972421 0.171247718272669 821/1514/5641/811/567 CANX/CTSL/LGMN/CALR/B2M 5 hsa05146 Amoebiasis 6/127 106/5868 0.0268220115307696 0.181793633708549 2335/3915/3912/1284/3911/1282 FN1/LAMC1/LAMB1/COL4A2/LAMA5/COL4A1 6 hsa05143 African trypanosomiasis 3/127 35/5868 0.0391765019535346 0.238706207224357 3039/3040/3043 HBA1/HBA2/HBB 3 hsa00533 Glycosaminoglycan biosynthesis - keratan sulfate 2/127 15/5868 0.0405980259196627 0.238706207224357 2683/10678 B4GALT1/B3GNT2 2 hsa00270 Cysteine and methionine metabolism 3/127 36/5868 0.0420821958396492 0.238706207224357 3939/10768/1788 LDHA/AHCYL1/DNMT3A 3 hsa05215 Prostate cancer 5/127 89/5868 0.0430453816306217 0.238706207224357 1956/3480/64764/7184/1499 EGFR/IGF1R/CREB3L2/HSP90B1/CTNNB1 5 hsa00531 Glycosaminoglycan degradation 2/127 19/5868 0.0625286091135521 0.331673491819711 2720/2799 GLB1/GNS 2 hsa04514 Cell adhesion molecules (CAMs) 6/127 133/5868 0.0677729996272223 0.337272388354099 3655/999/5792/3685/3688/1364 ITGA6/CDH1/PTPRF/ITGAV/ITGB1/CLDN4 6 hsa04144 Endocytosis 8/127 201/5868 0.0691131943348564 0.337272388354099 1956/4233/2321/3480/153/7037/8411/2348 EGFR/MET/FLT1/IGF1R/ADRB1/TFRC/EEA1/FOLR1 8 hsa04810 Regulation of actin cytoskeleton 8/127 213/5868 0.0897553481338443 0.421159710474192 2335/3655/1956/3693/3685/1730/3691/3688 FN1/ITGA6/EGFR/ITGB5/ITGAV/DIAPH2/ITGB4/ITGB1 8 hsa04974 Protein digestion and absorption 4/127 81/5868 0.0977828493940617 0.441833615780575 1284/1803/4311/1282 COL4A2/DPP4/MME/COL4A1 4 hsa05213 Endometrial cancer 3/127 52/5868 0.101951208779207 0.444215981109401 1956/999/1499 EGFR/CDH1/CTNNB1 3 hsa00601 Glycosphingolipid biosynthesis - lacto and neolacto series 2/127 26/5868 0.107891185119548 0.453887054640857 2683/10678 B4GALT1/B3GNT2 2 hsa00052 Galactose metabolism 2/127 27/5868 0.11493639054818 0.464180760689793 2720/2683 GLB1/B4GALT1 2 hsa05130 Pathogenic Escherichia coli infection 3/127 56/5868 0.120368239799283 0.464180760689793 999/3688/1499 CDH1/ITGB1/CTNNB1 3 hsa04640 Hematopoietic cell lineage 4/127 88/5868 0.122557294460945 0.464180760689793 3655/1441/4311/7037 ITGA6/CSF3R/MME/TFRC 4 hsa04970 Salivary secretion 4/127 89/5868 0.126299031535313 0.464180760689793 4069/490/493/153 LYZ/ATP2B1/ATP2B4/ADRB1 4 hsa05216 Thyroid cancer 2/127 29/5868 0.129361851339778 0.464180760689793 999/1499 CDH1/CTNNB1 2 hsa04360 Axon guidance 5/127 129/5868 0.146863705287973 0.51192491557522 80031/4233/57556/8829/3688 SEMA6D/MET/SEMA6A/NRP1/ITGB1 5 hsa00640 Propanoate metabolism 2/127 32/5868 0.151719774730023 0.514161458807302 3939/3030 LDHA/HADHA 2 hsa05145 Toxoplasmosis 5/127 132/5868 0.157141070321509 0.518140826465515 3915/3655/3912/3911/3688 LAMC1/ITGA6/LAMB1/LAMA5/ITGB1 5 hsa05214 Glioma 3/127 65/5868 0.165711170411897 0.53202007342767 1956/3480/1021 EGFR/IGF1R/CDK6 3 hsa05120 Epithelial cell signaling in Helicobacter pylori infection 3/127 68/5868 0.181822447548558 0.568777912844208 1956/4233/525 EGFR/MET/ATP6V1B1 3 hsa00290 Valine, leucine and isoleucine biosynthesis 1/127 11/5868 0.214073917163546 0.637510784281867 55699 IARS2 1 hsa00600 Sphingolipid metabolism 2/127 40/5868 0.214245427504562 0.637510784281867 2720/8613 GLB1/PLPP3 2 hsa00380 Tryptophan metabolism 2/127 42/5868 0.23027735796981 0.653345062146902 26/3030 AOC1/HADHA 2 hsa05219 Bladder cancer 2/127 42/5868 0.23027735796981 0.653345062146902 1956/999 EGFR/CDH1 2 hsa04670 Leukocyte transendothelial migration 4/127 116/5868 0.242406687570058 0.672127633716978 3688/1499/394/1364 ITGB1/CTNNB1/ARHGAP5/CLDN4 4 hsa00604 Glycosphingolipid biosynthesis - ganglio series 1/127 15/5868 0.280071396022262 0.759304673660356 2720 GLB1 1 hsa00511 Other glycan degradation 1/127 17/5868 0.310977470994316 0.797747259011773 2720 GLB1 1 hsa04614 Renin-angiotensin system 1/127 17/5868 0.310977470994316 0.797747259011773 4311 MME 1 hsa05323 Rheumatoid arthritis 3/127 91/5868 0.314848496890651 0.797747259011773 2321/1514/525 FLT1/CTSL/ATP6V1B1 3 hsa05110 Vibrio cholerae infection 2/127 54/5868 0.326945597955645 0.797747259011773 525/9601 ATP6V1B1/PDIA4 2 hsa05223 Non-small cell lung cancer 2/127 54/5868 0.326945597955645 0.797747259011773 1956/1021 EGFR/CDK6 2 hsa05217 Basal cell carcinoma 2/127 55/5868 0.334918893904458 0.801178530516546 1499/1857 CTNNB1/DVL3 2 hsa01040 Biosynthesis of unsaturated fatty acids 1/127 21/5868 0.368894965008831 0.848682812885435 3030 HADHA 1 hsa04916 Melanogenesis 3/127 101/5868 0.374431575754912 0.848682812885435 64764/1499/1857 CREB3L2/CTNNB1/DVL3 3 hsa00410 beta-Alanine metabolism 1/127 22/5868 0.382602907448352 0.848682812885435 3030 HADHA 1 hsa00532 Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate 1/127 22/5868 0.382602907448352 0.848682812885435 79586 CHPF 1 hsa04320 Dorso-ventral axis formation 1/127 24/5868 0.409138760737813 0.857915660541476 1956 EGFR 1 hsa04977 Vitamin digestion and absorption 1/127 24/5868 0.409138760737813 0.857915660541476 6573 SLC19A1 1 hsa00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 1/127 26/5868 0.434542693961337 0.857915660541476 2135 EXTL2 1 hsa04115 p53 signaling pathway 2/127 68/5868 0.435300309758825 0.857915660541476 1021/4194 CDK6/MDM4 2 hsa04610 Complement and coagulation cascades 2/127 69/5868 0.442703741915506 0.857915660541476 2153/4179 F5/CD46 2 hsa04966 Collecting duct acid secretion 1/127 27/5868 0.446835244092612 0.857915660541476 525 ATP6V1B1 1 hsa03320 PPAR signaling pathway 2/127 70/5868 0.450054117005364 0.857915660541476 4973/11001 OLR1/SLC27A2 2 hsa05211 Renal cell carcinoma 2/127 70/5868 0.450054117005364 0.857915660541476 4233/6513 MET/SLC2A1 2 hsa05212 Pancreatic cancer 2/127 70/5868 0.450054117005364 0.857915660541476 1956/1021 EGFR/CDK6 2 hsa00340 Histidine metabolism 1/127 29/5868 0.470630508376347 0.877934676478477 26 AOC1 1 hsa00512 Mucin type O-Glycan biosynthesis 1/127 30/5868 0.482144453475885 0.877934676478477 63917 GALNT11 1 hsa00650 Butanoate metabolism 1/127 30/5868 0.482144453475885 0.877934676478477 3030 HADHA 1 hsa05010 Alzheimer's disease 4/127 167/5868 0.491087251453977 0.881068304079195 4035/348/351/4311 LRP1/APOE/APP/MME 4 hsa00260 Glycine, serine and threonine metabolism 1/127 32/5868 0.504432158144918 0.886789829853697 2731 GLDC 1 hsa00564 Glycerophospholipid metabolism 2/127 80/5868 0.520415145290632 0.886789829853697 8613/10162 PLPP3/LPCAT3 2 hsa05020 Prion diseases 1/127 35/5868 0.536091395085182 0.886789829853697 3915 LAMC1 1 hsa04020 Calcium signaling pathway 4/127 177/5868 0.537189503421222 0.886789829853697 1956/490/493/153 EGFR/ATP2B1/ATP2B4/ADRB1 4 hsa00565 Ether lipid metabolism 1/127 36/5868 0.546191925313911 0.886789829853697 8613 PLPP3 1 hsa00620 Pyruvate metabolism 1/127 40/5868 0.584458117940179 0.886789829853697 3939 LDHA 1 hsa04540 Gap junction 2/127 90/5868 0.584586123201476 0.886789829853697 1956/153 EGFR/ADRB1 2 hsa00071 Fatty acid degradation 1/127 43/5868 0.611040561447507 0.886789829853697 3030 HADHA 1 hsa00280 Valine, leucine and isoleucine degradation 1/127 44/5868 0.619520878820239 0.886789829853697 3030 HADHA 1 hsa00310 Lysine degradation 1/127 44/5868 0.619520878820239 0.886789829853697 3030 HADHA 1 hsa04962 Vasopressin-regulated water reabsorption 1/127 44/5868 0.619520878820239 0.886789829853697 64764 CREB3L2 1 hsa04310 Wnt signaling pathway 3/127 150/5868 0.635782742544259 0.886789829853697 6907/1499/1857 TBL1X/CTNNB1/DVL3 3 hsa00514 Other types of O-glycan biosynthesis 1/127 46/5868 0.635935046794093 0.886789829853697 2683 B4GALT1 1 hsa04975 Fat digestion and absorption 1/127 46/5868 0.635935046794093 0.886789829853697 8613 PLPP3 1 hsa04330 Notch signaling pathway 1/127 47/5868 0.643876690397176 0.886789829853697 1857 DVL3 1 hsa04912 GnRH signaling pathway 2/127 101/5868 0.647677281275142 0.886789829853697 1956/4214 EGFR/MAP3K1 2 hsa04972 Pancreatic secretion 2/127 101/5868 0.647677281275142 0.886789829853697 490/493 ATP2B1/ATP2B4 2 hsa04630 Jak-STAT signaling pathway 3/127 155/5868 0.657879758579295 0.886789829853697 1441/3572/1442 CSF3R/IL6ST/CSH1 3 hsa00561 Glycerolipid metabolism 1/127 50/5868 0.66668489310245 0.886789829853697 8613 PLPP3 1 hsa04060 Cytokine-cytokine receptor interaction 5/127 265/5868 0.686547535373721 0.886789829853697 1956/4233/2321/1441/3572 EGFR/MET/FLT1/CSF3R/IL6ST 5 hsa00330 Arginine and proline metabolism 1/127 54/5868 0.69485625387946 0.886789829853697 26 AOC1 1 hsa00500 Starch and sucrose metabolism 1/127 54/5868 0.69485625387946 0.886789829853697 178 AGL 1 hsa04114 Oocyte meiosis 2/127 112/5868 0.70300864819447 0.886789829853697 3480/9748 IGF1R/SLK 2 hsa00140 Steroid hormone biosynthesis 1/127 56/5868 0.708042788656915 0.886789829853697 412 STS 1 hsa04340 Hedgehog signaling pathway 1/127 56/5868 0.708042788656915 0.886789829853697 4036 LRP2 1 hsa04621 NOD-like receptor signaling pathway 1/127 58/5868 0.720663772239657 0.886789829853697 7184 HSP90B1 1 hsa05131 Shigellosis 1/127 61/5868 0.738587216075688 0.886789829853697 3688 ITGB1 1 hsa05210 Colorectal cancer 1/127 62/5868 0.744304354625436 0.886789829853697 1499 CTNNB1 1 hsa00970 Aminoacyl-tRNA biosynthesis 1/127 63/5868 0.749897421618645 0.886789829853697 55699 IARS2 1 hsa04110 Cell cycle 2/127 124/5868 0.755004150477229 0.886789829853697 1021/1028 CDK6/CDKN1C 2 hsa00010 Glycolysis / Gluconeogenesis 1/127 65/5868 0.760721970467958 0.886789829853697 3939 LDHA 1 hsa04920 Adipocytokine signaling pathway 1/127 68/5868 0.776093218558461 0.886789829853697 6513 SLC2A1 1 hsa04530 Tight junction 2/127 132/5868 0.785182309449739 0.886789829853697 1499/1364 CTNNB1/CLDN4 2 hsa04730 Long-term depression 1/127 70/5868 0.785792264225685 0.886789829853697 3480 IGF1R 1 hsa05416 Viral myocarditis 1/127 70/5868 0.785792264225685 0.886789829853697 1605 DAG1 1 hsa03018 RNA degradation 1/127 71/5868 0.790484292932711 0.886789829853697 170506 DHX36 1 hsa04622 RIG-I-like receptor signaling pathway 1/127 71/5868 0.790484292932711 0.886789829853697 4214 MAP3K1 1 hsa04976 Bile secretion 1/127 71/5868 0.790484292932711 0.886789829853697 6513 SLC2A1 1 hsa05160 Hepatitis C 2/127 134/5868 0.792202686404109 0.886789829853697 1956/1364 EGFR/CLDN4 2 hsa05140 Leishmaniasis 1/127 72/5868 0.795074338611087 0.886789829853697 3688 ITGB1 1 hsa04120 Ubiquitin mediated proteolysis 2/127 135/5868 0.795637107330829 0.886789829853697 4214/57448 MAP3K1/BIRC6 2 hsa05220 Chronic myeloid leukemia 1/127 73/5868 0.799564600687759 0.886789829853697 1021 CDK6 1 hsa04146 Peroxisome 1/127 79/5868 0.824528079641478 0.906238069515859 11001 SLC27A2 1 hsa04914 Progesterone-mediated oocyte maturation 1/127 86/5868 0.849776985331609 0.921020744804796 3480 IGF1R 1 hsa04012 ErbB signaling pathway 1/127 87/5868 0.853076591499525 0.921020744804796 1956 EGFR 1 hsa04666 Fc gamma R-mediated phagocytosis 1/127 94/5868 0.874244967060932 0.935595491065208 8613 PLPP3 1 hsa04620 Toll-like receptor signaling pathway 1/127 102/5868 0.894753894328787 0.945857019357655 6696 SPP1 1 hsa05142 Chagas disease (American trypanosomiasis) 1/127 104/5868 0.89933946102859 0.945857019357655 811 CALR 1 hsa04010 MAPK signaling pathway 3/127 268/5868 0.934961394780135 0.968792645442601 1956/4214/57551 EGFR/MAP3K1/TAOK1 3 hsa04722 Neurotrophin signaling pathway 1/127 127/5868 0.939760399119893 0.968792645442601 4214 MAP3K1 1 hsa00190 Oxidative phosphorylation 1/127 132/5868 0.94613715723666 0.968792645442601 525 ATP6V1B1 1 hsa04910 Insulin signaling pathway 1/127 138/5868 0.952910798796001 0.968792645442601 5792 PTPRF 1 hsa05016 Huntington's disease 1/127 183/5868 0.982892694609432 0.983509398628724 64764 CREB3L2 1 hsa04080 Neuroactive ligand-receptor interaction 2/127 272/5868 0.983509398628724 0.983509398628724 153/1442 ADRB1/CSH1 2