ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	geneID	Count
GO:0032496	response to lipopolysaccharide	34/319	343/18722	1.17523011071007e-16	4.83137098512909e-13	NFKBIA/FOS/TNFAIP3/CXCL8/JUND/CCL3/JUN/TRIB1/IL1B/NR4A1/ICAM1/SOD2/CXCL2/TNF/NLRP3/LITAF/PDE4B/CHMP5/HNRNPA0/ZFP36/PRDX3/AKIRIN2/HMGB2/SNCA/RIPK2/PTGS2/PPBP/CEBPB/PTGER4/IL1A/C5AR1/PF4/S100A8/HMGB1	34
GO:0002237	response to molecule of bacterial origin	34/319	363/18722	6.56940318026015e-16	1.35034082370247e-12	NFKBIA/FOS/TNFAIP3/CXCL8/JUND/CCL3/JUN/TRIB1/IL1B/NR4A1/ICAM1/SOD2/CXCL2/TNF/NLRP3/LITAF/PDE4B/CHMP5/HNRNPA0/ZFP36/PRDX3/AKIRIN2/HMGB2/SNCA/RIPK2/PTGS2/PPBP/CEBPB/PTGER4/IL1A/C5AR1/PF4/S100A8/HMGB1	34
GO:0002181	cytoplasmic translation	22/319	148/18722	8.28212643681249e-15	1.13492739272454e-11	RPL39/ETF1/RPL17/YBX3/RPS10/RPS29/RPL34/RPS3A/RPL36A/RPL3/RPL23/RPS15/RPL7/RPS15A/RPL18A/RPS28/RPS20/RPL9/RPL5/UBA52/RPS6/RPL36	22
GO:0001819	positive regulation of cytokine production	32/319	467/18722	2.44474421594885e-11	2.01170782813778e-08	CD83/CCL3/IL1B/HIF1A/TNF/NLRP3/PDE4B/OSM/AKIRIN2/HMGB2/RIPK2/PTGS2/FFAR2/HMOX1/CEBPB/CD81/PTGER4/EGR1/EREG/RGCC/IL1A/FCN1/HLA-DPB1/MNDA/C5AR1/ISG15/PF4/NR4A3/C3/HLA-A/HMGB1/THBS1	32
GO:0060326	cell chemotaxis	26/319	310/18722	2.44673781091922e-11	2.01170782813778e-08	CXCL8/CCL3/DUSP1/TMSB4X/CCL4/CXCR4/NR4A1/CCL3L3/VEGFA/CXCL2/PDE4B/TREM1/HBEGF/SBDS/GPR183/CCRL2/HMGB2/FFAR2/PPBP/CCL20/C5AR1/PF4/S100A8/HMGB1/THBS1/NCKAP1L	26
GO:0032103	positive regulation of response to external stimulus	30/319	427/18722	5.77170295457109e-11	3.95457847437363e-08	NFKBIA/CXCL8/NFKBIZ/CCL3/IL1B/TMSB4X/CCL4/CXCR4/VEGFA/TNF/OSM/AKIRIN2/HMGB2/SNCA/RIPK2/PTGS2/FFAR2/NMI/CEBPB/CD81/PTGER4/EREG/FCN1/MNDA/C5AR1/S100A8/C3/HMGB1/THBS1/NCKAP1L	30
GO:0071222	cellular response to lipopolysaccharide	21/319	209/18722	7.63553319235391e-11	4.48423956482385e-08	NFKBIA/TNFAIP3/CXCL8/CCL3/TRIB1/IL1B/ICAM1/CXCL2/TNF/NLRP3/LITAF/PDE4B/CHMP5/ZFP36/HMGB2/RIPK2/PPBP/CEBPB/IL1A/PF4/HMGB1	21
GO:2001233	regulation of apoptotic signaling pathway	27/319	356/18722	9.98348640315312e-11	5.13026407542031e-08	TNFAIP3/ATF3/G0S2/NR4A2/IL1B/HIF1A/ICAM1/PLAUR/SOD2/MCL1/PPIF/TNF/CTNNB1/DNAJA1/VDAC2/HMGB2/PMAIP1/PTGS2/SKIL/ERP29/HMOX1/YBX3/IL1A/TIMP3/PF4/S100A8/THBS1	27
GO:0071219	cellular response to molecule of bacterial origin	21/319	221/18722	2.17380408901281e-10	8.85419984605341e-08	NFKBIA/TNFAIP3/CXCL8/CCL3/TRIB1/IL1B/ICAM1/CXCL2/TNF/NLRP3/LITAF/PDE4B/CHMP5/ZFP36/HMGB2/RIPK2/PPBP/CEBPB/IL1A/PF4/HMGB1	21
GO:0050900	leukocyte migration	27/319	369/18722	2.23469874837704e-10	8.85419984605341e-08	CXCL8/CCL3/DUSP1/CCL4/CXCR4/ICAM1/CCL3L3/VEGFA/CXCL2/TNF/NLRP3/PDE4B/TREM1/SBDS/GPR183/FFAR2/PPBP/HMOX1/CD81/PTGER4/CCL20/C5AR1/PF4/S100A8/HMGB1/THBS1/NCKAP1L	27
GO:0007159	leukocyte cell-cell adhesion	27/319	371/18722	2.52135391113485e-10	8.85419984605341e-08	CD83/KLF4/NFKBIZ/IL1B/MAP3K8/ICAM1/OLR1/TNF/NLRP3/BCL6/PRNP/RIPK2/SEMA4D/CEBPB/CD81/ZMIZ1/IL1A/HES1/HLA-DPB1/HLA-DQA1/NR4A3/S100A8/HLA-A/HLA-DRA/HMGB1/HLA-DRB1/NCKAP1L	27
GO:0071216	cellular response to biotic stimulus	22/319	246/18722	2.58453899665874e-10	8.85419984605341e-08	NFKBIA/TNFAIP3/CXCL8/CCL3/TRIB1/IL1B/ICAM1/PPP1R15B/CXCL2/TNF/NLRP3/LITAF/PDE4B/CHMP5/ZFP36/HMGB2/RIPK2/PPBP/CEBPB/IL1A/PF4/HMGB1	22
GO:0030595	leukocyte chemotaxis	21/319	230/18722	4.55390252395105e-10	1.44008409815098e-07	CXCL8/CCL3/DUSP1/CCL4/CXCR4/CCL3L3/VEGFA/CXCL2/PDE4B/TREM1/SBDS/GPR183/FFAR2/PPBP/CCL20/C5AR1/PF4/S100A8/HMGB1/THBS1/NCKAP1L	21
GO:0022407	regulation of cell-cell adhesion	29/319	448/18722	8.3415274534903e-10	2.44942995437847e-07	CD83/KLF4/NFKBIZ/IL1B/MAP3K8/ICAM1/PLAUR/VEGFA/TNF/NLRP3/MYADM/BCL6/PRNP/RIPK2/CEBPB/CD81/ZMIZ1/RGCC/IL1A/IL1RN/HES1/HLA-DPB1/HLA-DQA1/NR4A3/HLA-A/HLA-DRA/HMGB1/HLA-DRB1/NCKAP1L	29
GO:1903039	positive regulation of leukocyte cell-cell adhesion	21/319	239/18722	9.20941477268602e-10	2.52399360870082e-07	CD83/NFKBIZ/IL1B/MAP3K8/ICAM1/TNF/NLRP3/BCL6/RIPK2/CD81/ZMIZ1/IL1A/HES1/HLA-DPB1/HLA-DQA1/NR4A3/HLA-A/HLA-DRA/HMGB1/HLA-DRB1/NCKAP1L	21
GO:1902107	positive regulation of leukocyte differentiation	17/319	157/18722	1.59991827758287e-09	3.86897884655481e-07	FOS/CD83/NFKBIZ/JUN/TRIB1/TNF/NLRP3/KLF10/BCL6/ID2/RIPK2/ZMIZ1/PF4/HLA-DRA/HMGB1/HLA-DRB1/NCKAP1L	17
GO:1903708	positive regulation of hemopoiesis	17/319	157/18722	1.59991827758287e-09	3.86897884655481e-07	FOS/CD83/NFKBIZ/JUN/TRIB1/TNF/NLRP3/KLF10/BCL6/ID2/RIPK2/ZMIZ1/PF4/HLA-DRA/HMGB1/HLA-DRB1/NCKAP1L	17
GO:2001234	negative regulation of apoptotic signaling pathway	20/319	224/18722	1.76727049878793e-09	4.03624945584288e-07	TNFAIP3/NR4A2/IL1B/HIF1A/ICAM1/PLAUR/SOD2/MCL1/PPIF/TNF/CTNNB1/DNAJA1/VDAC2/HMGB2/PTGS2/HMOX1/YBX3/IL1A/PF4/THBS1	20
GO:0030099	myeloid cell differentiation	26/319	381/18722	2.15644329624534e-09	4.66586231098137e-07	NFKBIA/FOS/CCL3/JUN/TRIB1/JUNB/HIF1A/VEGFA/TNF/KLF10/ZFP36/PRDX3/GPR183/CTNNB1/BCL6/ID2/HMGB2/KLF2/CEBPB/CD81/ISG15/PF4/HMGB1/RPS6/HLA-DRB1/NCKAP1L	26
GO:0045444	fat cell differentiation	20/319	229/18722	2.59539133441793e-09	5.06849290021611e-07	KLF4/NR4A2/METRNL/NR4A1/TNF/PIM1/ZFP36/ID2/ARL4A/PTGS2/FFAR2/CEBPB/HNRNPU/LRG1/HES1/PLAC8/ADIRF/NR4A3/RETN/PIAS1	20
GO:0031349	positive regulation of defense response	22/319	278/18722	2.61147151870746e-09	5.06849290021611e-07	NFKBIA/NFKBIZ/CCL3/IL1B/TNF/OSM/AKIRIN2/HMGB2/SNCA/RIPK2/PTGS2/FFAR2/NMI/CEBPB/CD81/PTGER4/EREG/FCN1/MNDA/S100A8/C3/HMGB1	22
GO:0019221	cytokine-mediated signaling pathway	29/319	472/18722	2.75302538974155e-09	5.06849290021611e-07	NFKBIA/TNFAIP3/CXCL8/CCL3/IL1B/TMSB4X/CCL4/CXCR4/BIRC3/HIF1A/CCL3L3/CXCL2/TNF/OSM/LIMS1/CCRL2/RIPK2/PPBP/IFNGR2/NMI/HSP90AB1/EGR1/EREG/IL1A/IL1RN/CCL20/ISG15/PF4/STAT6	29
GO:0050727	regulation of inflammatory response	26/319	386/18722	2.8356929385787e-09	5.06849290021611e-07	NFKBIA/TNFAIP3/KLF4/NFKBIZ/CCL3/SOCS3/IL1B/TMSB4X/METRNL/BIRC3/TNF/NLRP3/OSM/ZFP36/BCL6/SNCA/PTGS2/FFAR2/NMI/CEBPB/CD81/PTGER4/APOE/S100A8/C3/HLA-DRB1	26
GO:0006979	response to oxidative stress	28/319	446/18722	3.26251171639378e-09	5.58841069420617e-07	FOS/TNFAIP3/KLF4/JUN/DUSP1/NR4A2/HIF1A/PPP1R15B/KDM6B/SOD2/MCL1/PPIF/HNRNPM/PRDX3/AREG/LDHA/CTNNB1/PRNP/BTG1/SNCA/PTGS2/KLF2/HMOX1/APOE/PAGE4/NR4A3/STAT6/NDUFA6	28
GO:1903037	regulation of leukocyte cell-cell adhesion	24/319	336/18722	3.75108618015975e-09	5.90834466451335e-07	CD83/KLF4/NFKBIZ/IL1B/MAP3K8/ICAM1/TNF/NLRP3/BCL6/PRNP/RIPK2/CEBPB/CD81/ZMIZ1/IL1A/HES1/HLA-DPB1/HLA-DQA1/NR4A3/HLA-A/HLA-DRA/HMGB1/HLA-DRB1/NCKAP1L	24
GO:0050867	positive regulation of cell activation	27/319	420/18722	3.80396260882861e-09	5.90834466451335e-07	CD83/NFKBIZ/JUND/CCL3/IL1B/MAP3K8/CDKN1A/NLRP3/GPR183/IRS2/BCL6/RIPK2/CD81/ZMIZ1/PLEK/IL1A/HES1/HLA-DPB1/HLA-DQA1/NR4A3/HLA-A/HLA-DRA/HMGB1/THBS1/STAT6/HLA-DRB1/NCKAP1L	27
GO:0022409	positive regulation of cell-cell adhesion	22/319	284/18722	3.88045015669814e-09	5.90834466451335e-07	CD83/NFKBIZ/IL1B/MAP3K8/ICAM1/PLAUR/TNF/NLRP3/BCL6/RIPK2/CD81/ZMIZ1/IL1A/HES1/HLA-DPB1/HLA-DQA1/NR4A3/HLA-A/HLA-DRA/HMGB1/HLA-DRB1/NCKAP1L	22
GO:1903706	regulation of hemopoiesis	25/319	367/18722	4.61056955300039e-09	6.7693040829945e-07	NFKBIA/FOS/CD83/NFKBIZ/CCL3/JUN/TRIB1/HIF1A/TNF/NLRP3/KLF10/ZFP36/CTNNB1/BCL6/ID2/HMGB2/RIPK2/CEBPB/ZMIZ1/ISG15/PF4/HLA-DRA/HMGB1/HLA-DRB1/NCKAP1L	25
GO:0042110	T cell activation	29/319	487/18722	5.5723314305528e-09	7.89926017620778e-07	CD83/NFKBIZ/IL1B/MAP3K8/ICAM1/NLRP3/GPR183/CTNNB1/BCL6/PRNP/RIPK2/CEBPB/CD81/ZMIZ1/PTGER4/EGR1/IL1A/CD48/HES1/HLA-DPB1/HLA-DQA1/HLA-A/HLA-DRA/HMGB1/STAT6/RPS6/HLA-DRB1/PPP3CA/NCKAP1L	29
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	12/319	78/18722	7.74174496501245e-09	1.04339813332741e-06	KLF4/BIRC3/NR4A1/PLAUR/DNAJB6/VEGFA/TNF/PRDX3/SNCA/PTGS2/SERPINB9/THBS1	12
GO:0097529	myeloid leukocyte migration	19/319	220/18722	7.86799857288976e-09	1.04339813332741e-06	CXCL8/CCL3/DUSP1/CCL4/CCL3L3/VEGFA/CXCL2/PDE4B/TREM1/PPBP/CD81/PTGER4/CCL20/C5AR1/PF4/S100A8/HMGB1/THBS1/NCKAP1L	19
GO:0002286	T cell activation involved in immune response	14/319	114/18722	8.8403337419607e-09	1.1025713540049e-06	NFKBIZ/ICAM1/NLRP3/GPR183/BCL6/RIPK2/CD81/PTGER4/HLA-DRA/HMGB1/STAT6/RPS6/HLA-DRB1/NCKAP1L	14
GO:0045785	positive regulation of cell adhesion	27/319	437/18722	8.85060926347886e-09	1.1025713540049e-06	CD83/NFKBIZ/IL1B/FN1/MAP3K8/ICAM1/PLAUR/VEGFA/TNF/NLRP3/MYADM/BCL6/LIMS1/RIPK2/CD81/ZMIZ1/IL1A/HES1/HLA-DPB1/HLA-DQA1/NR4A3/HLA-A/HLA-DRA/HMGB1/HLA-DRB1/PPP3CA/NCKAP1L	27
GO:0002696	positive regulation of leukocyte activation	26/319	409/18722	9.42674721886152e-09	1.13980464166881e-06	CD83/NFKBIZ/JUND/CCL3/IL1B/MAP3K8/CDKN1A/NLRP3/GPR183/IRS2/BCL6/RIPK2/CD81/ZMIZ1/IL1A/HES1/HLA-DPB1/HLA-DQA1/NR4A3/HLA-A/HLA-DRA/HMGB1/THBS1/STAT6/HLA-DRB1/NCKAP1L	26
GO:0045936	negative regulation of phosphate metabolic process	27/319	441/18722	1.07265096210382e-08	1.2599051729168e-06	TNFAIP3/PPP1R15A/GADD45B/DUSP1/SOCS3/TRIB1/IL1B/DDIT4/PPP1R15B/CDKN1A/TNF/PRDX3/SAMSN1/MYADM/IRS2/DNAJA1/PRNP/NPM1/MIDN/SNCA/SEMA4D/HNRNPU/PLEK/APOE/FBLN1/APOC1/NCKAP1L	27
GO:0010563	negative regulation of phosphorus metabolic process	27/319	442/18722	1.12504131569173e-08	1.28473468022464e-06	TNFAIP3/PPP1R15A/GADD45B/DUSP1/SOCS3/TRIB1/IL1B/DDIT4/PPP1R15B/CDKN1A/TNF/PRDX3/SAMSN1/MYADM/IRS2/DNAJA1/PRNP/NPM1/MIDN/SNCA/SEMA4D/HNRNPU/PLEK/APOE/FBLN1/APOC1/NCKAP1L	27
GO:0043367	CD4-positive, alpha-beta T cell differentiation	12/319	83/18722	1.59997601309058e-08	1.77770307832848e-06	CD83/NFKBIZ/NLRP3/GPR183/BCL6/RIPK2/PTGER4/HLA-DRA/HMGB1/STAT6/HLA-DRB1/NCKAP1L	12
GO:0002819	regulation of adaptive immune response	17/319	183/18722	1.6568346160436e-08	1.79243344909348e-06	TNFAIP3/NFKBIZ/IL1B/TNF/NLRP3/SAMSN1/BCL6/RIPK2/CD81/CD48/C3/HLA-A/HLA-DRA/HMGB1/STAT6/HLA-DRB1/NCKAP1L	17
GO:0035710	CD4-positive, alpha-beta T cell activation	13/319	102/18722	1.91962216171558e-08	2.02347864277251e-06	CD83/NFKBIZ/NLRP3/GPR183/BCL6/RIPK2/CD81/PTGER4/HLA-DRA/HMGB1/STAT6/HLA-DRB1/NCKAP1L	13
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	18/319	209/18722	2.04914548255587e-08	2.06046699427935e-06	KLF4/BIRC3/NR4A1/PLAUR/CYCS/DNAJB6/VEGFA/ANP32B/TNF/NLRP3/PRDX3/PMAIP1/SNCA/PTGS2/SERPINB9/S100A8/HMGB1/THBS1	18
GO:0050729	positive regulation of inflammatory response	15/319	142/18722	2.08009469414472e-08	2.06046699427935e-06	NFKBIA/NFKBIZ/CCL3/IL1B/TNF/OSM/SNCA/PTGS2/FFAR2/NMI/CEBPB/CD81/PTGER4/S100A8/C3	15
GO:0030593	neutrophil chemotaxis	13/319	103/18722	2.16364460799126e-08	2.06046699427935e-06	CXCL8/CCL3/CCL4/CCL3L3/CXCL2/PDE4B/TREM1/PPBP/CCL20/C5AR1/PF4/S100A8/NCKAP1L	13
GO:0045639	positive regulation of myeloid cell differentiation	13/319	103/18722	2.16364460799126e-08	2.06046699427935e-06	FOS/JUN/TRIB1/HIF1A/TNF/KLF10/ID2/HMGB2/ISG15/PF4/HMGB1/HLA-DRB1/NCKAP1L	13
GO:0045637	regulation of myeloid cell differentiation	18/319	210/18722	2.20708077093818e-08	2.06046699427935e-06	NFKBIA/FOS/CCL3/JUN/TRIB1/HIF1A/TNF/KLF10/ZFP36/CTNNB1/ID2/HMGB2/CEBPB/ISG15/PF4/HMGB1/HLA-DRB1/NCKAP1L	18
GO:0070555	response to interleukin-1	15/319	143/18722	2.28853316917673e-08	2.06046699427935e-06	CXCL8/CCL3/IL1B/CCL4/HIF1A/ICAM1/CCL3L3/SNCA/RIPK2/KLF2/CEBPB/EGR1/IL1RN/CCL20/GBP1	15
GO:2000116	regulation of cysteine-type endopeptidase activity	19/319	235/18722	2.30555781408052e-08	2.06046699427935e-06	KLF4/BIRC3/NR4A1/PLAUR/CYCS/DNAJB6/VEGFA/ANP32B/TNF/NLRP3/PRDX3/PMAIP1/SNCA/RIPK2/PTGS2/SERPINB9/S100A8/HMGB1/THBS1	19
GO:2000117	negative regulation of cysteine-type endopeptidase activity	12/319	86/18722	2.41328966044039e-08	2.11085825405754e-06	KLF4/BIRC3/NR4A1/PLAUR/DNAJB6/VEGFA/TNF/PRDX3/SNCA/PTGS2/SERPINB9/THBS1	12
GO:0097193	intrinsic apoptotic signaling pathway	21/319	288/18722	2.54948752494142e-08	2.18352983646546e-06	PPP1R15A/BCL2A1/DDIT4/HIF1A/PLAUR/SOD2/MCL1/CDKN1A/PPIF/TNF/DNAJA1/VDAC2/PMAIP1/DDX5/PTGS2/SKIL/ERP29/HMOX1/CEBPB/YBX3/S100A8	21
GO:0071621	granulocyte chemotaxis	14/319	125/18722	2.92765012038455e-08	2.456238703041e-06	CXCL8/CCL3/CCL4/CCL3L3/CXCL2/PDE4B/TREM1/PPBP/CCL20/C5AR1/PF4/S100A8/THBS1/NCKAP1L	14
GO:0042542	response to hydrogen peroxide	15/319	146/18722	3.03306273674746e-08	2.49378418215376e-06	TNFAIP3/KLF4/JUN/DUSP1/PPP1R15B/KDM6B/SOD2/PPIF/PRDX3/AREG/LDHA/KLF2/HMOX1/NR4A3/STAT6	15
GO:0002683	negative regulation of immune system process	26/319	434/18722	3.14980978967627e-08	2.53899373438415e-06	TNFAIP3/CCL3/DUSP1/TRIB1/TNF/SAMSN1/CTNNB1/BCL6/ID2/PRNP/NMI/HMOX1/CEBPB/SERPINB9/PTGER4/TSC22D3/MNDA/ISG15/GBP1/HLA-A/HMGB1/THBS1/DGKZ/STAT6/HLA-DRB1/NCKAP1L	26
GO:0050870	positive regulation of T cell activation	18/319	216/18722	3.41433703637883e-08	2.69929606856796e-06	CD83/NFKBIZ/IL1B/MAP3K8/NLRP3/BCL6/RIPK2/CD81/ZMIZ1/IL1A/HES1/HLA-DPB1/HLA-DQA1/HLA-A/HLA-DRA/HMGB1/HLA-DRB1/NCKAP1L	18
GO:0097530	granulocyte migration	15/319	148/18722	3.64529410878776e-08	2.82751020400499e-06	CXCL8/CCL3/CCL4/CCL3L3/CXCL2/PDE4B/TREM1/PPBP/PTGER4/CCL20/C5AR1/PF4/S100A8/THBS1/NCKAP1L	15
GO:0070663	regulation of leukocyte proliferation	19/319	245/18722	4.50286092776684e-08	3.4280113470462e-06	TNFAIP3/IL1B/CDKN1A/GPR183/CTNNB1/IRS2/BCL6/PRNP/RIPK2/CEBPB/CD81/IL1A/HES1/HLA-DPB1/MNDA/HLA-A/HMGB1/HLA-DRB1/NCKAP1L	19
GO:2001236	regulation of extrinsic apoptotic signaling pathway	15/319	151/18722	4.77592512949337e-08	3.56978694679041e-06	TNFAIP3/ATF3/G0S2/IL1B/ICAM1/MCL1/TNF/HMGB2/PMAIP1/SKIL/HMOX1/IL1A/TIMP3/PF4/THBS1	15
GO:0000302	response to reactive oxygen species	18/319	222/18722	5.20290022296192e-08	3.81948621724937e-06	FOS/TNFAIP3/KLF4/JUN/DUSP1/HIF1A/PPP1R15B/KDM6B/SOD2/PPIF/PRDX3/AREG/LDHA/KLF2/HMOX1/APOE/NR4A3/STAT6	18
GO:0002526	acute inflammatory response	13/319	112/18722	5.98697041595746e-08	4.31797111929844e-06	IL1B/FN1/ICAM1/TNF/NLRP3/TREM1/OSM/PTGS2/FFAR2/CEBPB/IL1A/S100A8/C3	13
GO:0050670	regulation of lymphocyte proliferation	18/319	225/18722	6.3881351091351e-08	4.52786610925075e-06	IL1B/CDKN1A/GPR183/CTNNB1/IRS2/BCL6/PRNP/RIPK2/CEBPB/CD81/IL1A/HES1/HLA-DPB1/MNDA/HLA-A/HMGB1/HLA-DRB1/NCKAP1L	18
GO:0071347	cellular response to interleukin-1	13/319	113/18722	6.66291212849874e-08	4.64258165428107e-06	CXCL8/CCL3/IL1B/CCL4/HIF1A/ICAM1/CCL3L3/KLF2/CEBPB/EGR1/IL1RN/CCL20/GBP1	13
GO:1902105	regulation of leukocyte differentiation	20/319	279/18722	7.30836726901099e-08	4.9268932639402e-06	FOS/CD83/NFKBIZ/CCL3/JUN/TRIB1/TNF/NLRP3/KLF10/CTNNB1/BCL6/ID2/RIPK2/CEBPB/ZMIZ1/PF4/HLA-DRA/HMGB1/HLA-DRB1/NCKAP1L	20
GO:0032944	regulation of mononuclear cell proliferation	18/319	227/18722	7.31064191438464e-08	4.9268932639402e-06	IL1B/CDKN1A/GPR183/CTNNB1/IRS2/BCL6/PRNP/RIPK2/CEBPB/CD81/IL1A/HES1/HLA-DPB1/MNDA/HLA-A/HMGB1/HLA-DRB1/NCKAP1L	18
GO:0048660	regulation of smooth muscle cell proliferation	16/319	180/18722	8.16284985690085e-08	5.4124960905999e-06	TNFAIP3/KLF4/JUN/TRIB1/SOD2/CDKN1A/TNF/HBEGF/CTNNB1/ID2/PTGS2/HMOX1/EREG/APOE/NR4A3/THBS1	16
GO:1990868	response to chemokine	12/319	97/18722	9.51870829811301e-08	6.11428278336603e-06	CXCL8/CCL3/DUSP1/CCL4/CXCR4/HIF1A/CCL3L3/CXCL2/CCRL2/PPBP/CCL20/PF4	12
GO:1990869	cellular response to chemokine	12/319	97/18722	9.51870829811301e-08	6.11428278336603e-06	CXCL8/CCL3/DUSP1/CCL4/CXCR4/HIF1A/CCL3L3/CXCL2/CCRL2/PPBP/CCL20/PF4	12
GO:0048659	smooth muscle cell proliferation	16/319	184/18722	1.10817587594719e-07	7.00878619387525e-06	TNFAIP3/KLF4/JUN/TRIB1/SOD2/CDKN1A/TNF/HBEGF/CTNNB1/ID2/PTGS2/HMOX1/EREG/APOE/NR4A3/THBS1	16
GO:1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors	9/319	49/18722	1.22076617245015e-07	7.60389353779178e-06	TNFAIP3/ATF3/ICAM1/HMGB2/PMAIP1/SKIL/HMOX1/TIMP3/THBS1	9
GO:0044403	biological process involved in symbiotic interaction	20/319	290/18722	1.37405079831146e-07	8.43092959978868e-06	CXCL8/CCL3/JUN/CCL4/FN1/CXCR4/ICAM1/CHMP2B/TREM1/SNX3/HSP90AB1/SERPINB9/CHD1/CD81/TRIM22/FCN1/APOE/PF4/IFIT1/HLA-DRB1	20
GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	11/319	82/18722	1.41196915005945e-07	8.53618408219763e-06	TNFAIP3/ATF3/ICAM1/TNF/GABARAP/HMGB2/PMAIP1/SKIL/HMOX1/TIMP3/THBS1	11
GO:0051090	regulation of DNA-binding transcription factor activity	25/319	440/18722	1.6132505937548e-07	9.54153218799928e-06	NFKBIA/TNFAIP3/KLF4/TRIB1/IL1B/TMSB4X/BHLHE40/SGK1/ICAM1/VEGFA/TNF/NLRP3/PIM1/PRDX3/CTNNB1/ID2/PRNP/NPM1/RIPK2/HMOX1/RGCC/TRIM22/HES1/S100A8/PPP3CA	25
GO:0042093	T-helper cell differentiation	10/319	66/18722	1.6246831747992e-07	9.54153218799928e-06	NFKBIZ/NLRP3/GPR183/BCL6/RIPK2/PTGER4/HLA-DRA/HMGB1/STAT6/HLA-DRB1	10
GO:1990266	neutrophil migration	13/319	122/18722	1.66175058208982e-07	9.6217699196778e-06	CXCL8/CCL3/CCL4/CCL3L3/CXCL2/PDE4B/TREM1/PPBP/CCL20/C5AR1/PF4/S100A8/NCKAP1L	13
GO:0043370	regulation of CD4-positive, alpha-beta T cell differentiation	9/319	51/18722	1.75449264324481e-07	1.00176656338603e-05	CD83/NFKBIZ/NLRP3/BCL6/RIPK2/HLA-DRA/HMGB1/HLA-DRB1/NCKAP1L	9
GO:0051348	negative regulation of transferase activity	19/319	268/18722	1.85228044707353e-07	1.0431130024547e-05	TNFAIP3/GADD45B/DUSP1/TRIB1/IL1B/CDKN1A/ZFP36/PRDX3/IRS2/DNAJA1/NPM1/MIDN/SNCA/HNRNPU/RPL23/RPS15/APOE/RPS20/RPL5	19
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	10/319	67/18722	1.88118538737805e-07	1.04507474696097e-05	CD83/NFKBIZ/NLRP3/BCL6/RIPK2/CD81/HLA-DRA/HMGB1/HLA-DRB1/NCKAP1L	10
GO:1903320	regulation of protein modification by small protein conjugation or removal	18/319	242/18722	1.91956296858119e-07	1.05217644851164e-05	TNFAIP3/BIRC3/HIF1A/GABARAP/CTNNB1/DNAJA1/NPM1/RIPK2/NMI/HSP90AB1/ZMIZ1/EGR1/RPL23/RPS15/ISG15/RPS20/RPL5/PIAS1	18
GO:0002822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	15/319	168/18722	1.96592333945192e-07	1.06340932216932e-05	TNFAIP3/NFKBIZ/IL1B/TNF/NLRP3/BCL6/RIPK2/CD81/C3/HLA-A/HLA-DRA/HMGB1/STAT6/HLA-DRB1/NCKAP1L	15
GO:0016032	viral process	24/319	415/18722	2.08314691759106e-07	1.11218402314504e-05	CXCL8/CCL3/JUN/CCL4/CXCR4/ICAM1/CHMP1B/TNF/CHMP2B/CHMP5/ZFP36/DDX5/SNX3/DEK/HSP90AB1/CHD1/CD81/SSB/TRIM22/FCN1/ISG15/APOE/IFIT1/HLA-DRB1	24
GO:0002294	CD4-positive, alpha-beta T cell differentiation involved in immune response	10/319	68/18722	2.1725817058857e-07	1.14506197344822e-05	NFKBIZ/NLRP3/GPR183/BCL6/RIPK2/PTGER4/HLA-DRA/HMGB1/STAT6/HLA-DRB1	10
GO:0097191	extrinsic apoptotic signaling pathway	17/319	219/18722	2.29799450768033e-07	1.18301601451995e-05	TNFAIP3/ATF3/G0S2/BCL2A1/IL1B/ICAM1/MCL1/TNF/GABARAP/HMGB2/PMAIP1/SKIL/HMOX1/IL1A/TIMP3/PF4/THBS1	17
GO:0001818	negative regulation of cytokine production	22/319	357/18722	2.30540595399698e-07	1.18301601451995e-05	CD83/TNFAIP3/KLF4/TMSB4X/FN1/TNF/NLRP3/ZFP36/BCL6/PRNP/SRGN/KLF2/NMI/HMOX1/HSP90AB1/PTGER4/RGCC/GBP1/HMGB1/THBS1/HLA-DRB1/NCKAP1L	22
GO:0048872	homeostasis of number of cells	19/319	272/18722	2.33092428061581e-07	1.18301601451995e-05	TNFAIP3/HIF1A/VEGFA/PDE4B/ZFP36/GPR183/BCL6/ID2/HMGB2/PMAIP1/HCAR2/SKIL/KLF2/HMOX1/TSC22D3/ISG15/HMGB1/RPS6/NCKAP1L	19
GO:0050863	regulation of T cell activation	21/319	329/18722	2.44235770736428e-07	1.22287284769818e-05	CD83/NFKBIZ/IL1B/MAP3K8/NLRP3/CTNNB1/BCL6/PRNP/RIPK2/CEBPB/CD81/ZMIZ1/IL1A/HES1/HLA-DPB1/HLA-DQA1/HLA-A/HLA-DRA/HMGB1/HLA-DRB1/NCKAP1L	21
GO:0002287	alpha-beta T cell activation involved in immune response	10/319	69/18722	2.50286507445987e-07	1.22287284769818e-05	NFKBIZ/NLRP3/GPR183/BCL6/RIPK2/PTGER4/HLA-DRA/HMGB1/STAT6/HLA-DRB1	10
GO:0002293	alpha-beta T cell differentiation involved in immune response	10/319	69/18722	2.50286507445987e-07	1.22287284769818e-05	NFKBIZ/NLRP3/GPR183/BCL6/RIPK2/PTGER4/HLA-DRA/HMGB1/STAT6/HLA-DRB1	10
GO:2000516	positive regulation of CD4-positive, alpha-beta T cell activation	8/319	39/18722	2.52844057539152e-07	1.22287284769818e-05	CD83/NFKBIZ/NLRP3/RIPK2/CD81/HLA-DRA/HLA-DRB1/NCKAP1L	8
GO:0070371	ERK1 and ERK2 cascade	21/319	330/18722	2.56853675911236e-07	1.22782030426871e-05	ATF3/KLF4/CCL3/DUSP1/IL1B/CCL4/FN1/ICAM1/CCL3L3/TNF/GPR183/RIPK2/PTGER4/CCL20/C5AR1/APOE/TIMP3/GBP1/FBLN1/HMGB1/HLA-DRB1	21
GO:0001776	leukocyte homeostasis	11/319	87/18722	2.61821051689393e-07	1.23717970516678e-05	TNFAIP3/HIF1A/PDE4B/GPR183/PMAIP1/HCAR2/SKIL/TSC22D3/HMGB1/RPS6/NCKAP1L	11
GO:0051251	positive regulation of lymphocyte activation	22/319	362/18722	2.92603905803512e-07	1.36139758758613e-05	CD83/NFKBIZ/IL1B/MAP3K8/CDKN1A/NLRP3/GPR183/IRS2/BCL6/RIPK2/CD81/ZMIZ1/IL1A/HES1/HLA-DPB1/HLA-DQA1/HLA-A/HLA-DRA/HMGB1/STAT6/HLA-DRB1/NCKAP1L	22
GO:0070098	chemokine-mediated signaling pathway	11/319	88/18722	2.9473214618138e-07	1.36139758758613e-05	CXCL8/CCL3/CCL4/CXCR4/HIF1A/CCL3L3/CXCL2/CCRL2/PPBP/CCL20/PF4	11
GO:1903131	mononuclear cell differentiation	24/319	426/18722	3.35487932830939e-07	1.53243432429777e-05	CD83/NFKBIZ/JUN/IL1B/KLF6/NFIL3/VEGFA/NLRP3/GPR183/CTNNB1/BCL6/ID2/RIPK2/CEBPB/ZMIZ1/PTGER4/EGR1/IL1A/HLA-DRA/HMGB1/STAT6/RPS6/HLA-DRB1/NCKAP1L	24
GO:0062197	cellular response to chemical stress	21/319	337/18722	3.63375459056455e-07	1.64157858481438e-05	FOS/TNFAIP3/KLF4/JUN/NR4A2/HIF1A/KDM6B/SOD2/MCL1/PPIF/PRDX3/CTNNB1/DNAJA1/SNCA/PTGS2/KLF2/HMOX1/YBX3/PAGE4/NR4A3/STAT6	21
GO:0001701	in utero embryonic development	22/319	367/18722	3.6972334838872e-07	1.64180709833044e-05	KLF4/SOCS3/JUNB/HIF1A/DNAJB6/VEGFA/CMIP/SBDS/GRB2/CTNNB1/BRK1/SYF2/YTHDC1/SKIL/KLF2/CEBPB/YBX3/ZMIZ1/MAFF/HES1/YBX1/DAD1	22
GO:0034612	response to tumor necrosis factor	18/319	253/18722	3.71413427741986e-07	1.64180709833044e-05	NFKBIA/TNFAIP3/CXCL8/CCL3/TMSB4X/CCL4/BIRC3/ICAM1/CCL3L3/TNF/ZFP36/LIMS1/PTGS2/KLF2/YBX3/CCL20/GBP1/THBS1	18
GO:0070372	regulation of ERK1 and ERK2 cascade	20/319	309/18722	3.80750093944782e-07	1.66517408107127e-05	ATF3/KLF4/CCL3/DUSP1/IL1B/CCL4/FN1/ICAM1/CCL3L3/TNF/GPR183/RIPK2/CCL20/C5AR1/APOE/TIMP3/GBP1/FBLN1/HMGB1/HLA-DRB1	20
GO:0052547	regulation of peptidase activity	25/319	461/18722	3.86975623937411e-07	1.67458609474389e-05	KLF4/FN1/BIRC3/NR4A1/PLAUR/CYCS/DNAJB6/VEGFA/ANP32B/TNF/NLRP3/PRDX3/AKIRIN2/PRNP/PMAIP1/SNCA/RIPK2/PTGS2/SERPINB9/TIMP3/S100A8/C3/FBLN1/HMGB1/THBS1	25
GO:0007568	aging	21/319	339/18722	4.00523233679622e-07	1.69747527181126e-05	FOS/JUND/JUN/BCL2A1/ICAM1/SOD2/CDKN1A/LITAF/GRB2/BCL6/ID2/LIMS1/PRNP/NPM1/SNCA/PTGS2/ZMIZ1/SERP1/YBX1/RETN/PPP3CA	21
GO:0048545	response to steroid hormone	21/319	339/18722	4.00523233679622e-07	1.69747527181126e-05	FOS/FOSB/DUSP1/DDIT4/ICAM1/YWHAH/CDKN1A/TNF/ZFP36/AREG/DNAJA1/HMGB2/DDX5/PTGS2/HNRNPU/ZMIZ1/IL1RN/SPP1/NR4A3/HMGB1/THBS1	21
GO:0009266	response to temperature stimulus	15/319	178/18722	4.16798716883619e-07	1.74842808684547e-05	NFKBIA/FOS/METRNL/IER5/CXCR4/SOD2/DNAJB6/CDKN1A/DNAJA1/PTGS2/HMOX1/HSP90AB1/IL1A/PLAC8/THBS1	15
GO:0071356	cellular response to tumor necrosis factor	17/319	229/18722	4.33265044591818e-07	1.799144038704e-05	NFKBIA/TNFAIP3/CXCL8/CCL3/TMSB4X/CCL4/BIRC3/ICAM1/CCL3L3/TNF/ZFP36/LIMS1/KLF2/YBX3/CCL20/GBP1/THBS1	17
GO:0045765	regulation of angiogenesis	21/319	342/18722	4.62811988569864e-07	1.88869110679903e-05	TNFAIP3/KLF4/CXCL8/IL1B/CXCR4/HIF1A/VEGFA/TNF/PGK1/CTNNB1/BTG1/KLF2/HMOX1/LRG1/RGCC/IL1A/C5AR1/PF4/C3/HMGB1/THBS1	21
GO:0030217	T cell differentiation	18/319	257/18722	4.67834062094813e-07	1.88869110679903e-05	CD83/NFKBIZ/IL1B/NLRP3/GPR183/CTNNB1/BCL6/RIPK2/ZMIZ1/PTGER4/EGR1/IL1A/HLA-DRA/HMGB1/STAT6/RPS6/HLA-DRB1/NCKAP1L	18
GO:0046632	alpha-beta T cell differentiation	12/319	112/18722	4.69618084302668e-07	1.88869110679903e-05	CD83/NFKBIZ/NLRP3/GPR183/BCL6/RIPK2/PTGER4/HLA-DRA/HMGB1/STAT6/HLA-DRB1/NCKAP1L	12
GO:0046631	alpha-beta T cell activation	14/319	156/18722	4.7320648017587e-07	1.88869110679903e-05	CD83/NFKBIZ/NLRP3/GPR183/BCL6/RIPK2/CD81/PTGER4/HLA-A/HLA-DRA/HMGB1/STAT6/HLA-DRB1/NCKAP1L	14
GO:0002262	myeloid cell homeostasis	14/319	157/18722	5.11661895767423e-07	2.02254043605757e-05	HIF1A/VEGFA/PDE4B/ZFP36/BCL6/ID2/HMGB2/HCAR2/KLF2/HMOX1/ISG15/HMGB1/RPS6/NCKAP1L	14
GO:0002292	T cell differentiation involved in immune response	10/319	75/18722	5.57486670511005e-07	2.1722315886225e-05	NFKBIZ/NLRP3/GPR183/BCL6/RIPK2/PTGER4/HLA-DRA/HMGB1/STAT6/HLA-DRB1	10
GO:0046651	lymphocyte proliferation	19/319	288/18722	5.60098633894392e-07	2.1722315886225e-05	IL1B/CDKN1A/GPR183/CTNNB1/IRS2/BCL6/PRNP/RIPK2/CEBPB/CD81/IL1A/HES1/HLA-DPB1/MNDA/HLA-A/HMGB1/RPS6/HLA-DRB1/NCKAP1L	19
GO:0070661	leukocyte proliferation	20/319	318/18722	5.9952518257862e-07	2.3034093697016e-05	TNFAIP3/IL1B/CDKN1A/GPR183/CTNNB1/IRS2/BCL6/PRNP/RIPK2/CEBPB/CD81/IL1A/HES1/HLA-DPB1/MNDA/HLA-A/HMGB1/RPS6/HLA-DRB1/NCKAP1L	20
GO:1901342	regulation of vasculature development	21/319	348/18722	6.14802251702644e-07	2.34023338587923e-05	TNFAIP3/KLF4/CXCL8/IL1B/CXCR4/HIF1A/VEGFA/TNF/PGK1/CTNNB1/BTG1/KLF2/HMOX1/LRG1/RGCC/IL1A/C5AR1/PF4/C3/HMGB1/THBS1	21
GO:1901214	regulation of neuron death	20/319	319/18722	6.29868930619352e-07	2.37558823282216e-05	FOS/CCL3/JUN/NR4A2/DDIT4/HIF1A/SOD2/MCL1/TNF/CTNNB1/PRNP/SNCA/HMOX1/HSP90AB1/CEBPB/EGR1/SET/C5AR1/APOE/NR4A3	20
GO:0050671	positive regulation of lymphocyte proliferation	13/319	137/18722	6.43480218498303e-07	2.4048610711332e-05	IL1B/CDKN1A/GPR183/IRS2/BCL6/RIPK2/CD81/IL1A/HES1/HLA-DPB1/HLA-A/HMGB1/NCKAP1L	13
GO:0032943	mononuclear cell proliferation	19/319	291/18722	6.55437145670002e-07	2.42747937463908e-05	IL1B/CDKN1A/GPR183/CTNNB1/IRS2/BCL6/PRNP/RIPK2/CEBPB/CD81/IL1A/HES1/HLA-DPB1/MNDA/HLA-A/HMGB1/RPS6/HLA-DRB1/NCKAP1L	19
GO:0032946	positive regulation of mononuclear cell proliferation	13/319	138/18722	6.99666514633322e-07	2.56815093005142e-05	IL1B/CDKN1A/GPR183/IRS2/BCL6/RIPK2/CD81/IL1A/HES1/HLA-DPB1/HLA-A/HMGB1/NCKAP1L	13
GO:0043523	regulation of neuron apoptotic process	16/319	212/18722	7.62118036830722e-07	2.7726258844346e-05	CCL3/JUN/NR4A2/HIF1A/SOD2/MCL1/TNF/CTNNB1/PRNP/SNCA/HMOX1/HSP90AB1/CEBPB/SET/C5AR1/APOE	16
GO:0042326	negative regulation of phosphorylation	22/319	385/18722	8.28721547355551e-07	2.98848621156024e-05	TNFAIP3/GADD45B/DUSP1/SOCS3/TRIB1/IL1B/DDIT4/PPP1R15B/CDKN1A/PRDX3/SAMSN1/MYADM/IRS2/DNAJA1/PRNP/NPM1/MIDN/SNCA/SEMA4D/HNRNPU/APOE/FBLN1	22
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	7/319	32/18722	9.1136410801348e-07	3.25792856351601e-05	CD83/NFKBIZ/NLRP3/RIPK2/HLA-DRA/HLA-DRB1/NCKAP1L	7
GO:0002831	regulation of response to biotic stimulus	20/319	327/18722	9.28055861569917e-07	3.28899797147752e-05	TNFAIP3/TRIB1/BIRC3/AKIRIN2/HMGB2/RIPK2/FFAR2/NMI/HSP90AB1/SERPINB9/EREG/FCN1/MNDA/ISG15/APOE/IFIT1/HLA-A/HERC5/HMGB1/HLA-DRB1	20
GO:0032623	interleukin-2 production	9/319	62/18722	9.92613964649317e-07	3.45816610904521e-05	CD83/TNFAIP3/IL1B/PDE4B/ZFP36/PRNP/RIPK2/IL1A/GBP1	9
GO:0032663	regulation of interleukin-2 production	9/319	62/18722	9.92613964649317e-07	3.45816610904521e-05	CD83/TNFAIP3/IL1B/PDE4B/ZFP36/PRNP/RIPK2/IL1A/GBP1	9
GO:0042060	wound healing	23/319	422/18722	1.05113391141651e-06	3.63127017633047e-05	TNFAIP3/FN1/CXCR4/HIF1A/PLAUR/VEGFA/CDKN1A/TNF/HBEGF/HMOX1/TLN1/ANXA5/PLEK/EREG/IL1A/APOE/PF4/S100A8/FBLN1/HMGB1/THBS1/DGKZ/PPP3CA	23
GO:0043618	regulation of transcription from RNA polymerase II promoter in response to stress	8/319	47/18722	1.14797260007309e-06	3.93276279908373e-05	ATF3/JUN/HIF1A/VEGFA/KLF2/HMOX1/CEBPB/EGR1	8
GO:0002366	leukocyte activation involved in immune response	18/319	275/18722	1.25014012259337e-06	4.24737689585234e-05	NFKBIZ/CCL3/ICAM1/NLRP3/GPR183/BCL6/RIPK2/NMI/HMOX1/CD81/PTGER4/NR4A3/HLA-DRA/HMGB1/STAT6/RPS6/HLA-DRB1/NCKAP1L	18
GO:0033002	muscle cell proliferation	17/319	248/18722	1.31635910082147e-06	4.43569857662056e-05	TNFAIP3/KLF4/JUN/TRIB1/SOD2/CDKN1A/TNF/PIM1/HBEGF/CTNNB1/ID2/PTGS2/HMOX1/EREG/APOE/NR4A3/THBS1	17
GO:0009615	response to virus	21/319	367/18722	1.44801161281798e-06	4.83965507341033e-05	TNFAIP3/CCL4/DDIT4/CXCR4/BIRC3/HIF1A/BNIP3L/TNF/PMAIP1/IFNGR2/NMI/MX2/TRIM22/ISG15/IFI44L/IFI44/RPS15A/GBP1/IFIT3/IFIT1/HERC5	21
GO:0002263	cell activation involved in immune response	18/319	279/18722	1.5374259066457e-06	5.09706282437133e-05	NFKBIZ/CCL3/ICAM1/NLRP3/GPR183/BCL6/RIPK2/NMI/HMOX1/CD81/PTGER4/NR4A3/HLA-DRA/HMGB1/STAT6/RPS6/HLA-DRB1/NCKAP1L	18
GO:0051384	response to glucocorticoid	13/319	148/18722	1.55372703323593e-06	5.10989746690631e-05	FOS/FOSB/DUSP1/DDIT4/ICAM1/CDKN1A/TNF/ZFP36/AREG/PTGS2/HNRNPU/IL1RN/HMGB1	13
GO:0052548	regulation of endopeptidase activity	23/319	432/18722	1.56688097150679e-06	5.11226005862255e-05	KLF4/BIRC3/NR4A1/PLAUR/CYCS/DNAJB6/VEGFA/ANP32B/TNF/NLRP3/PRDX3/AKIRIN2/PRNP/PMAIP1/SNCA/RIPK2/PTGS2/SERPINB9/TIMP3/S100A8/C3/HMGB1/THBS1	23
GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	5/319	13/18722	1.60129614029546e-06	5.17956540837504e-05	ATF3/PMAIP1/SKIL/TIMP3/THBS1	5
GO:0046634	regulation of alpha-beta T cell activation	11/319	104/18722	1.61270827602045e-06	5.17956540837504e-05	CD83/NFKBIZ/NLRP3/BCL6/RIPK2/CD81/HLA-A/HLA-DRA/HMGB1/HLA-DRB1/NCKAP1L	11
GO:0070665	positive regulation of leukocyte proliferation	13/319	150/18722	1.80790092682488e-06	5.76145791486596e-05	IL1B/CDKN1A/GPR183/IRS2/BCL6/RIPK2/CD81/IL1A/HES1/HLA-DPB1/HLA-A/HMGB1/NCKAP1L	13
GO:0050873	brown fat cell differentiation	8/319	50/18722	1.87487601272785e-06	5.92893483717244e-05	METRNL/PIM1/ARL4A/PTGS2/CEBPB/HNRNPU/LRG1/PLAC8	8
GO:0050673	epithelial cell proliferation	23/319	437/18722	1.903671045074e-06	5.97403943992305e-05	TNFAIP3/NR4A1/HIF1A/VEGFA/TNF/ZFP36/AREG/CTNNB1/ID2/HMGB2/HMOX1/CEBPB/HMGN1/LRG1/EREG/RGCC/HES1/C5AR1/APOE/NR4A3/HMGB1/THBS1/STAT6	23
GO:0046635	positive regulation of alpha-beta T cell activation	9/319	67/18722	1.94166638446696e-06	6.0431644538441e-05	CD83/NFKBIZ/NLRP3/RIPK2/CD81/HLA-A/HLA-DRA/HLA-DRB1/NCKAP1L	9
GO:0030098	lymphocyte differentiation	21/319	374/18722	1.95509820569512e-06	6.0431644538441e-05	CD83/NFKBIZ/IL1B/KLF6/NFIL3/NLRP3/GPR183/CTNNB1/BCL6/ID2/RIPK2/ZMIZ1/PTGER4/EGR1/IL1A/HLA-DRA/HMGB1/STAT6/RPS6/HLA-DRB1/NCKAP1L	21
GO:0002253	activation of immune response	21/319	375/18722	2.03947366801152e-06	6.25692257402639e-05	NFKBIZ/IL1B/PDE4B/PRNP/RIPK2/FFAR2/CD81/RGCC/FCN1/HLA-DPB1/MNDA/C5AR1/NR4A3/GBP1/FPR3/C3/HLA-A/HMGB1/DGKZ/HLA-DRB1/NCKAP1L	21
GO:0002824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	11/319	107/18722	2.14108512882023e-06	6.52000071450369e-05	NFKBIZ/IL1B/TNF/NLRP3/RIPK2/CD81/C3/HLA-A/HLA-DRA/STAT6/HLA-DRB1	11
GO:0046637	regulation of alpha-beta T cell differentiation	9/319	68/18722	2.20471170522807e-06	6.66438957367103e-05	CD83/NFKBIZ/NLRP3/BCL6/RIPK2/HLA-DRA/HMGB1/HLA-DRB1/NCKAP1L	9
GO:0034599	cellular response to oxidative stress	18/319	288/18722	2.41406062922584e-06	7.24394397572806e-05	FOS/TNFAIP3/KLF4/JUN/NR4A2/HIF1A/KDM6B/SOD2/MCL1/PPIF/PRDX3/CTNNB1/SNCA/KLF2/HMOX1/PAGE4/NR4A3/STAT6	18
GO:0009895	negative regulation of catabolic process	19/319	320/18722	2.6978895188086e-06	8.03697377668272e-05	IL1B/DDIT4/MCL1/TNF/HNRNPA0/ZFP36/HCAR2/SNX3/SNCA/HMOX1/HSP90AB1/YBX3/HNRNPU/TOB1/RPL23/YBX1/TIMP3/RPL5/APOC1	19
GO:0045766	positive regulation of angiogenesis	14/319	181/18722	2.81905684267888e-06	8.27795905732348e-05	KLF4/CXCL8/IL1B/CXCR4/HIF1A/VEGFA/BTG1/HMOX1/LRG1/IL1A/C5AR1/C3/HMGB1/THBS1	14
GO:1904018	positive regulation of vasculature development	14/319	181/18722	2.81905684267888e-06	8.27795905732348e-05	KLF4/CXCL8/IL1B/CXCR4/HIF1A/VEGFA/BTG1/HMOX1/LRG1/IL1A/C5AR1/C3/HMGB1/THBS1	14
GO:0043620	regulation of DNA-templated transcription in response to stress	8/319	53/18722	2.96090560867415e-06	8.62804280071528e-05	ATF3/JUN/HIF1A/VEGFA/KLF2/HMOX1/CEBPB/EGR1	8
GO:0002573	myeloid leukocyte differentiation	15/319	208/18722	2.98025316881919e-06	8.62804280071528e-05	FOS/CCL3/JUN/TRIB1/JUNB/VEGFA/TNF/KLF10/GPR183/CTNNB1/ID2/CEBPB/CD81/PF4/HLA-DRB1	15
GO:0002685	regulation of leukocyte migration	15/319	210/18722	3.35356613874382e-06	9.59981230108739e-05	CXCL8/CCL3/DUSP1/CCL4/ICAM1/VEGFA/TNF/HMOX1/CD81/PTGER4/CCL20/C5AR1/HMGB1/THBS1/NCKAP1L	15
GO:0002821	positive regulation of adaptive immune response	11/319	112/18722	3.36261973086009e-06	9.59981230108739e-05	NFKBIZ/IL1B/TNF/NLRP3/RIPK2/CD81/C3/HLA-A/HLA-DRA/STAT6/HLA-DRB1	11
GO:0070997	neuron death	20/319	361/18722	4.21209164642665e-06	0.000119420060403172	FOS/CCL3/JUN/NR4A2/DDIT4/HIF1A/SOD2/MCL1/TNF/CTNNB1/PRNP/SNCA/HMOX1/HSP90AB1/CEBPB/EGR1/SET/C5AR1/APOE/NR4A3	20
GO:0045429	positive regulation of nitric oxide biosynthetic process	7/319	40/18722	4.49116705374054e-06	0.00012644667578262	KLF4/IL1B/ICAM1/TNF/PTGS2/KLF2/HSP90AB1	7
GO:0002437	inflammatory response to antigenic stimulus	9/319	74/18722	4.52144522988207e-06	0.00012644667578262	ICAM1/KDM6B/TNF/HMGB2/CD81/IL1RN/C3/HMGB1/HLA-DRB1	9
GO:2001242	regulation of intrinsic apoptotic signaling pathway	13/319	164/18722	4.88474963600582e-06	0.000135683822659594	HIF1A/PLAUR/SOD2/MCL1/PPIF/DNAJA1/VDAC2/PMAIP1/PTGS2/SKIL/ERP29/YBX3/S100A8	13
GO:0045088	regulation of innate immune response	15/319	218/18722	5.30055144959652e-06	0.000145309809662894	TNFAIP3/BIRC3/AKIRIN2/HMGB2/FFAR2/NMI/HSP90AB1/SERPINB9/EREG/FCN1/MNDA/ISG15/APOE/HLA-A/HMGB1	15
GO:0051402	neuron apoptotic process	16/319	246/18722	5.30998263679438e-06	0.000145309809662894	CCL3/JUN/NR4A2/HIF1A/SOD2/MCL1/TNF/CTNNB1/PRNP/SNCA/HMOX1/HSP90AB1/CEBPB/SET/C5AR1/APOE	16
GO:1904407	positive regulation of nitric oxide metabolic process	7/319	41/18722	5.33733428827464e-06	0.000145309809662894	KLF4/IL1B/ICAM1/TNF/PTGS2/KLF2/HSP90AB1	7
GO:0002763	positive regulation of myeloid leukocyte differentiation	8/319	58/18722	5.94735483788026e-06	0.000160155784990387	FOS/JUN/TRIB1/TNF/KLF10/ID2/PF4/HLA-DRB1	8
GO:0031960	response to corticosteroid	13/319	167/18722	5.9605534185184e-06	0.000160155784990387	FOS/FOSB/DUSP1/DDIT4/ICAM1/CDKN1A/TNF/ZFP36/AREG/PTGS2/HNRNPU/IL1RN/HMGB1	13
GO:1901216	positive regulation of neuron death	10/319	97/18722	6.07775515737173e-06	0.000161197751302937	FOS/CCL3/JUN/DDIT4/MCL1/TNF/CTNNB1/PRNP/SNCA/EGR1	10
GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	10/319	97/18722	6.07775515737173e-06	0.000161197751302937	TNFAIP3/IL1B/ICAM1/MCL1/TNF/HMGB2/HMOX1/IL1A/PF4/THBS1	10
GO:0002697	regulation of immune effector process	19/319	339/18722	6.21938001149052e-06	0.00016389661043101	NFKBIZ/IL1B/ICAM1/TNF/NLRP3/BCL6/RIPK2/FFAR2/HMOX1/SERPINB9/CD81/NR4A3/C3/HLA-A/HLA-DRA/HMGB1/STAT6/HLA-DRB1/NCKAP1L	19
GO:0002285	lymphocyte activation involved in immune response	14/319	194/18722	6.32581086555157e-06	0.000164717760953942	NFKBIZ/ICAM1/NLRP3/GPR183/BCL6/RIPK2/CD81/PTGER4/HLA-DRA/HMGB1/STAT6/RPS6/HLA-DRB1/NCKAP1L	14
GO:0002706	regulation of lymphocyte mediated immunity	13/319	168/18722	6.36300292880414e-06	0.000164717760953942	IL1B/TNF/NLRP3/BCL6/SERPINB9/CD81/C3/HLA-A/HLA-DRA/HMGB1/STAT6/HLA-DRB1/NCKAP1L	13
GO:0002675	positive regulation of acute inflammatory response	6/319	28/18722	6.41081044821958e-06	0.000164717760953942	IL1B/TNF/OSM/PTGS2/FFAR2/C3	6
GO:0010575	positive regulation of vascular endothelial growth factor production	6/319	28/18722	6.41081044821958e-06	0.000164717760953942	IL1B/HIF1A/PTGS2/IL1A/C5AR1/C3	6
GO:0002761	regulation of myeloid leukocyte differentiation	11/319	120/18722	6.59151712741622e-06	0.00016830886280005	FOS/CCL3/JUN/TRIB1/TNF/KLF10/CTNNB1/ID2/CEBPB/PF4/HLA-DRB1	11
GO:0002367	cytokine production involved in immune response	10/319	98/18722	6.6676129333732e-06	0.000169200967710477	IL1B/TNF/NLRP3/TREM1/BCL6/FFAR2/HMOX1/CD81/NR4A3/HLA-A	10
GO:0001890	placenta development	12/319	144/18722	6.78116001454989e-06	0.000171026679876163	SOCS3/JUNB/HIF1A/DNAJB6/PRDX3/GRB2/PTGS2/HSP90AB1/CEBPB/HES1/SPP1/RPS6	12
GO:0010038	response to metal ion	20/319	373/18722	6.85588002596754e-06	0.000171856846260686	FOS/FOSB/JUND/JUN/DUSP1/JUNB/HIF1A/ICAM1/SOD2/PPIF/PRNP/SNCA/PTGS2/HMOX1/IL1A/MT2A/S100A8/THBS1/AOC1/PPP3CA	20
GO:0002443	leukocyte mediated immunity	22/319	440/18722	7.25399239038255e-06	0.000180734319496137	CCL3/IL1B/ICAM1/TNF/NLRP3/TREM1/BCL6/HMOX1/SERPINB9/CD81/RNF19B/HLA-DPB1/HLA-DQA1/NR4A3/C3/HLA-A/HLA-DRA/HMGB1/STAT6/HLA-DRB1/TUBB/NCKAP1L	22
GO:0032602	chemokine production	10/319	99/18722	7.30634296784109e-06	0.000180942023739727	KLF4/IL1B/HIF1A/TNF/TREM1/RIPK2/FFAR2/HMOX1/EGR1/HMGB1	10
GO:0042129	regulation of T cell proliferation	13/319	171/18722	7.71807088165369e-06	0.00018999394846993	IL1B/CTNNB1/PRNP/RIPK2/CEBPB/CD81/IL1A/HES1/HLA-DPB1/HLA-A/HMGB1/HLA-DRB1/NCKAP1L	13
GO:0002703	regulation of leukocyte mediated immunity	15/319	226/18722	8.19914856047641e-06	0.000200635117453086	IL1B/ICAM1/TNF/NLRP3/BCL6/HMOX1/SERPINB9/CD81/C3/HLA-A/HLA-DRA/HMGB1/STAT6/HLA-DRB1/NCKAP1L	15
GO:0042098	T cell proliferation	14/319	199/18722	8.47432114672787e-06	0.000206141622687564	IL1B/CTNNB1/PRNP/RIPK2/CEBPB/CD81/IL1A/HES1/HLA-DPB1/HLA-A/HMGB1/RPS6/HLA-DRB1/NCKAP1L	14
GO:0051346	negative regulation of hydrolase activity	20/319	379/18722	8.6747417827084e-06	0.000209775667463025	PPP1R15A/KLF4/BIRC3/NR4A1/PLAUR/DNAJB6/VEGFA/PPIF/TNF/PRDX3/PRNP/SNCA/PTGS2/SEMA4D/SERPINB9/TIMP3/C3/THBS1/APOC1/NCKAP1L	20
GO:0006959	humoral immune response	18/319	317/18722	9.15052933208064e-06	0.000218708291187113	CD83/CXCL8/IL1B/RPL39/CXCL2/TNF/TREM1/GPR183/PPBP/HMGN2/CD81/RGCC/FCN1/PF4/DEFB1/C3/HLA-A/HLA-DRB1	18
GO:0019058	viral life cycle	18/319	317/18722	9.15052933208064e-06	0.000218708291187113	CXCL8/CXCR4/ICAM1/CHMP1B/TNF/CHMP2B/CHMP5/DDX5/SNX3/DEK/HSP90AB1/CD81/TRIM22/FCN1/ISG15/APOE/IFIT1/HLA-DRB1	18
GO:0001659	temperature homeostasis	13/319	174/18722	9.32157751626024e-06	0.000221414860940174	G0S2/IL1B/CXCR4/KDM6B/VEGFA/TNF/TLE3/PTGS2/CEBPB/EGR1/IL1A/PLAC8/STAT6	13
GO:0050678	regulation of epithelial cell proliferation	20/319	381/18722	9.37148766810758e-06	0.000221414860940174	TNFAIP3/NR4A1/HIF1A/VEGFA/TNF/ZFP36/AREG/CTNNB1/HMGB2/HMOX1/HMGN1/LRG1/EREG/RGCC/HES1/C5AR1/APOE/NR4A3/HMGB1/THBS1	20
GO:0071496	cellular response to external stimulus	18/319	320/18722	1.04023825928662e-05	0.000244366827652987	FOS/ATF3/JUN/NR4A2/IL1B/ICAM1/HNRNPA1/CDKN1A/GABARAPL1/PIM1/KLF10/MAP1LC3B/GABARAP/PMAIP1/PTGS2/HMOX1/PTGER4/AOC1	18
GO:0002429	immune response-activating cell surface receptor signaling pathway	17/319	291/18722	1.12284098566071e-05	0.00026079092045487	NFKBIZ/PDE4B/PRNP/RIPK2/FFAR2/CD81/FCN1/HLA-DPB1/MNDA/C5AR1/NR4A3/GBP1/FPR3/HLA-A/DGKZ/HLA-DRB1/NCKAP1L	17
GO:0002757	immune response-activating signal transduction	17/319	291/18722	1.12284098566071e-05	0.00026079092045487	NFKBIZ/PDE4B/PRNP/RIPK2/FFAR2/CD81/FCN1/HLA-DPB1/MNDA/C5AR1/NR4A3/GBP1/FPR3/HLA-A/DGKZ/HLA-DRB1/NCKAP1L	17
GO:0034101	erythrocyte homeostasis	11/319	129/18722	1.31905892693002e-05	0.000304643328573557	HIF1A/VEGFA/ZFP36/BCL6/ID2/HMGB2/KLF2/HMOX1/ISG15/RPS6/NCKAP1L	11
GO:0048608	reproductive structure development	21/319	424/18722	1.35347756186391e-05	0.000310846159599024	SOCS3/JUNB/HIF1A/ICAM1/DNAJB6/VEGFA/PRDX3/GRB2/CTNNB1/HMGB2/PTGS2/BASP1/HSP90AB1/CEBPB/YBX3/EREG/HES1/SPP1/C3/RETN/RPS6	21
GO:0061458	reproductive system development	21/319	427/18722	1.50413122003625e-05	0.000343526858087169	SOCS3/JUNB/HIF1A/ICAM1/DNAJB6/VEGFA/PRDX3/GRB2/CTNNB1/HMGB2/PTGS2/BASP1/HSP90AB1/CEBPB/YBX3/EREG/HES1/SPP1/C3/RETN/RPS6	21
GO:0002673	regulation of acute inflammatory response	7/319	48/18722	1.57833723794643e-05	0.000355751063420962	IL1B/TNF/NLRP3/OSM/PTGS2/FFAR2/C3	7
GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	7/319	48/18722	1.57833723794643e-05	0.000355751063420962	ATF3/G0S2/TNF/PMAIP1/SKIL/TIMP3/THBS1	7
GO:0045600	positive regulation of fat cell differentiation	8/319	66/18722	1.58361577733e-05	0.000355751063420962	METRNL/PIM1/ZFP36/ID2/PTGS2/CEBPB/HNRNPU/ADIRF	8
GO:0002764	immune response-regulating signaling pathway	22/319	468/18722	1.8927272096506e-05	0.000422880519504002	NFKBIA/TNFAIP3/NFKBIZ/BIRC3/PDE4B/PRNP/RIPK2/FFAR2/NMI/CD81/FCN1/HLA-DPB1/MNDA/C5AR1/NR4A3/GBP1/FPR3/HLA-A/HMGB1/DGKZ/HLA-DRB1/NCKAP1L	22
GO:0002687	positive regulation of leukocyte migration	11/319	135/18722	2.02711689100817e-05	0.000450458245347816	CXCL8/CCL3/CCL4/ICAM1/VEGFA/TNF/CCL20/C5AR1/HMGB1/THBS1/NCKAP1L	11
GO:0046638	positive regulation of alpha-beta T cell differentiation	7/319	50/18722	2.07965792006752e-05	0.00045964912416116	CD83/NFKBIZ/NLRP3/RIPK2/HLA-DRA/HLA-DRB1/NCKAP1L	7
GO:0001906	cell killing	13/319	188/18722	2.13428376063669e-05	0.000469200028875798	ICAM1/TREM1/HSP90AB1/SERPINB9/HMGN2/RNF19B/PF4/C3/HLA-A/HLA-DRA/HLA-DRB1/TUBB/NCKAP1L	13
GO:0032609	interferon-gamma production	10/319	112/18722	2.1841738884621e-05	0.000475086711929507	IL1B/TNF/PDE4B/PRNP/RIPK2/HLA-DPB1/ISG15/HLA-A/HMGB1/HLA-DRB1	10
GO:0032649	regulation of interferon-gamma production	10/319	112/18722	2.1841738884621e-05	0.000475086711929507	IL1B/TNF/PDE4B/PRNP/RIPK2/HLA-DPB1/ISG15/HLA-A/HMGB1/HLA-DRB1	10
GO:0034605	cellular response to heat	8/319	69/18722	2.20565556556924e-05	0.000477234212108165	IER5/DNAJB6/CDKN1A/PTGS2/HMOX1/HSP90AB1/IL1A/THBS1	8
GO:0031668	cellular response to extracellular stimulus	15/319	246/18722	2.24216793971236e-05	0.000482594366500394	FOS/ATF3/JUN/NR4A2/ICAM1/HNRNPA1/CDKN1A/GABARAPL1/PIM1/KLF10/MAP1LC3B/GABARAP/PMAIP1/HMOX1/AOC1	15
GO:0045862	positive regulation of proteolysis	19/319	372/18722	2.29281670000836e-05	0.000489686405848677	TRIB1/IL1B/FN1/CYCS/ANP32B/TNF/NLRP3/GABARAP/AKIRIN2/PMAIP1/SNCA/RIPK2/SUMO2/RNF19B/APOE/S100A8/FBLN1/HMGB1/PIAS1	19
GO:0031667	response to nutrient levels	22/319	474/18722	2.29894128749197e-05	0.000489686405848677	ATF3/JUN/ICAM1/SOD2/HNRNPA1/CDKN1A/GABARAPL1/PIM1/KLF10/MAP1LC3B/GABARAP/ZFP36/LDHA/PMAIP1/PTGS2/HMOX1/SPP1/APOE/PAGE4/CSH1/AOC1/DAD1	22
GO:0001660	fever generation	4/319	11/18722	2.48351992930043e-05	0.000524790894389988	IL1B/TNF/PTGS2/IL1A	4
GO:0045582	positive regulation of T cell differentiation	9/319	91/18722	2.4892781417185e-05	0.000524790894389988	CD83/NFKBIZ/NLRP3/BCL6/RIPK2/ZMIZ1/HLA-DRA/HLA-DRB1/NCKAP1L	9
GO:0001503	ossification	20/319	408/18722	2.51874861785072e-05	0.000526631386995708	JUND/CCL3/JUNB/HIF1A/TNF/KLF10/SBDS/AREG/CTNNB1/SRGN/DDX5/PTGS2/SEMA4D/CEBPB/HNRNPU/PTGER4/TOB1/SPP1/RPS15/ISG15	20
GO:0050792	regulation of viral process	12/319	164/18722	2.53023185356406e-05	0.000526631386995708	CXCL8/CXCR4/TNF/CHMP2B/ZFP36/DDX5/SNX3/TRIM22/FCN1/ISG15/IFIT1/HLA-DRB1	12
GO:0001933	negative regulation of protein phosphorylation	18/319	342/18722	2.53643917842739e-05	0.000526631386995708	TNFAIP3/GADD45B/DUSP1/SOCS3/TRIB1/IL1B/DDIT4/PPP1R15B/CDKN1A/SAMSN1/MYADM/DNAJA1/PRNP/NPM1/SNCA/SEMA4D/APOE/FBLN1	18
GO:0032722	positive regulation of chemokine production	8/319	71/18722	2.72495622806009e-05	0.000562929399676133	IL1B/HIF1A/TNF/RIPK2/FFAR2/HMOX1/EGR1/HMGB1	8
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	13/319	193/18722	2.81426640835301e-05	0.000578472460236962	ICAM1/VEGFA/TNF/HBEGF/OSM/AREG/PRNP/RIPK2/SEMA4D/CD81/EREG/HES1/CSH1	13
GO:0010951	negative regulation of endopeptidase activity	15/319	252/18722	2.96812220224037e-05	0.000607062207632346	KLF4/BIRC3/NR4A1/PLAUR/DNAJB6/VEGFA/TNF/PRDX3/PRNP/SNCA/PTGS2/SERPINB9/TIMP3/C3/THBS1	15
GO:0034341	response to interferon-gamma	11/319	141/18722	3.04305738837565e-05	0.000619307372456055	CCL3/CCL4/ICAM1/CCL3L3/SNCA/IFNGR2/NMI/HSP90AB1/CCL20/GBP4/GBP1	11
GO:0002768	immune response-regulating cell surface receptor signaling pathway	17/319	315/18722	3.10336295443704e-05	0.000628469217029097	NFKBIZ/PDE4B/PRNP/RIPK2/FFAR2/CD81/FCN1/HLA-DPB1/MNDA/C5AR1/NR4A3/GBP1/FPR3/HLA-A/DGKZ/HLA-DRB1/NCKAP1L	17
GO:0030316	osteoclast differentiation	9/319	94/18722	3.23089258538913e-05	0.000651088206790917	FOS/CCL3/JUNB/TNF/KLF10/GPR183/CTNNB1/CEBPB/CD81	9
GO:0051101	regulation of DNA binding	10/319	118/18722	3.43795647703549e-05	0.000682793630820887	NFKBIA/KLF4/JUN/TMSB4X/PLAUR/CTNNB1/HMGB2/HMOX1/HES1/HMGB1	10
GO:0071346	cellular response to interferon-gamma	10/319	118/18722	3.43795647703549e-05	0.000682793630820887	CCL3/CCL4/ICAM1/CCL3L3/IFNGR2/NMI/HSP90AB1/CCL20/GBP4/GBP1	10
GO:0002449	lymphocyte mediated immunity	18/319	350/18722	3.4380511208933e-05	0.000682793630820887	IL1B/ICAM1/TNF/NLRP3/BCL6/SERPINB9/CD81/RNF19B/HLA-DPB1/HLA-DQA1/C3/HLA-A/HLA-DRA/HMGB1/STAT6/HLA-DRB1/TUBB/NCKAP1L	18
GO:0045861	negative regulation of proteolysis	18/319	351/18722	3.56876553828599e-05	0.000705345919610274	KLF4/BIRC3/NR4A1/PLAUR/DNAJB6/VEGFA/TNF/PRDX3/PRNP/SNCA/PTGS2/HSP90AB1/SERPINB9/RPL23/TIMP3/C3/RPL5/THBS1	18
GO:1904667	negative regulation of ubiquitin protein ligase activity	4/319	12/18722	3.67531246661964e-05	0.000722928686615949	RPL23/RPS15/RPS20/RPL5	4
GO:0002718	regulation of cytokine production involved in immune response	9/319	96/18722	3.82286329380973e-05	0.000748371000040561	IL1B/TNF/NLRP3/BCL6/FFAR2/HMOX1/CD81/NR4A3/HLA-A	9
GO:0061614	pri-miRNA transcription by RNA polymerase II	7/319	55/18722	3.92843416148423e-05	0.000765393025491074	FOS/KLF4/JUN/HIF1A/TNF/DDX5/EGR1	7
GO:0030218	erythrocyte differentiation	10/319	120/18722	3.97382378819467e-05	0.000770584414776805	HIF1A/VEGFA/ZFP36/BCL6/ID2/HMGB2/KLF2/ISG15/RPS6/NCKAP1L	10
GO:0002460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	18/319	356/18722	4.29097951160478e-05	0.000828179191183439	TNFAIP3/NFKBIZ/IL1B/ICAM1/TNF/NLRP3/BCL6/RIPK2/CD81/HLA-DPB1/HLA-DQA1/C3/HLA-A/HLA-DRA/HMGB1/STAT6/HLA-DRB1/NCKAP1L	18
GO:0032642	regulation of chemokine production	9/319	98/18722	4.50408650686313e-05	0.000861223238591364	KLF4/IL1B/HIF1A/TNF/RIPK2/FFAR2/HMOX1/EGR1/HMGB1	9
GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	9/319	98/18722	4.50408650686313e-05	0.000861223238591364	HIF1A/PLAUR/SOD2/MCL1/PPIF/DNAJA1/VDAC2/PTGS2/YBX3	9
GO:0036003	positive regulation of transcription from RNA polymerase II promoter in response to stress	5/319	24/18722	4.53303020651397e-05	0.000862744776804579	ATF3/HIF1A/VEGFA/KLF2/CEBPB	5
GO:0010466	negative regulation of peptidase activity	15/319	262/18722	4.64438100131001e-05	0.000879864068957855	KLF4/BIRC3/NR4A1/PLAUR/DNAJB6/VEGFA/TNF/PRDX3/PRNP/SNCA/PTGS2/SERPINB9/TIMP3/C3/THBS1	15
GO:0045622	regulation of T-helper cell differentiation	6/319	39/18722	4.74205019873874e-05	0.000893976262344502	NFKBIZ/NLRP3/BCL6/RIPK2/HLA-DRA/HLA-DRB1	6
GO:0031331	positive regulation of cellular catabolic process	20/319	427/18722	4.77636050405566e-05	0.000893976262344502	TNFAIP3/TRIB1/IL1B/HIF1A/BNIP3L/TNF/GABARAP/ZFP36/IRS2/SNCA/RIPK2/HMOX1/CD81/TOB1/TRIM22/SUMO2/RNF19B/APOE/HMGB1/PIAS1	20
GO:1901653	cellular response to peptide	18/319	359/18722	4.78411037985382e-05	0.000893976262344502	KLF4/SOCS3/NR4A2/IL1B/SRSF5/NR4A1/ICAM1/KLF10/CHMP5/GRB2/IRS2/PRNP/RIPK2/KLF2/RPL23/NR4A3/STAT6/CSH1	18
GO:0050852	T cell receptor signaling pathway	10/319	123/18722	4.91070718122589e-05	0.000913480417285956	NFKBIZ/PDE4B/PRNP/RIPK2/CD81/HLA-DPB1/GBP1/HLA-A/DGKZ/HLA-DRB1	10
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	15/319	264/18722	5.06514151265653e-05	0.000934377517208821	SOCS3/ICAM1/VEGFA/TNF/HBEGF/OSM/AREG/SAMSN1/PRNP/RIPK2/SEMA4D/CD81/EREG/HES1/CSH1	15
GO:0043534	blood vessel endothelial cell migration	12/319	176/18722	5.06850368128356e-05	0.000934377517208821	KLF4/TMSB4X/NR4A1/HIF1A/VEGFA/TNF/PTGS2/HMOX1/RGCC/APOE/HMGB1/THBS1	12
GO:0070486	leukocyte aggregation	4/319	13/18722	5.23761595665967e-05	0.000961242821331603	IL1B/SEMA4D/NR4A3/S100A8	4
GO:0002699	positive regulation of immune effector process	14/319	235/18722	5.4054749675305e-05	0.000987640337400796	NFKBIZ/IL1B/TNF/NLRP3/RIPK2/FFAR2/HMOX1/CD81/NR4A3/C3/HLA-A/HLA-DRA/STAT6/HLA-DRB1	14
GO:0051098	regulation of binding	18/319	363/18722	5.51959098535938e-05	0.00100402825401825	NFKBIA/KLF4/JUN/TMSB4X/PLAUR/CDKN1A/MAPRE1/CTNNB1/HMGB2/RIPK2/HMOX1/HSP90AB1/HES1/APOE/IFIT1/HMGB1/CCPG1/PPP3CA	18
GO:1901798	positive regulation of signal transduction by p53 class mediator	5/319	25/18722	5.58763013727972e-05	0.00101192720239458	PMAIP1/DDX5/RPL23/RPS15/RPS20	5
GO:0043535	regulation of blood vessel endothelial cell migration	11/319	151/18722	5.71586523045374e-05	0.00102624204883113	KLF4/TMSB4X/HIF1A/VEGFA/TNF/PTGS2/HMOX1/RGCC/APOE/HMGB1/THBS1	11
GO:0042102	positive regulation of T cell proliferation	9/319	101/18722	5.71660007741007e-05	0.00102624204883113	IL1B/RIPK2/CD81/IL1A/HES1/HLA-DPB1/HLA-A/HMGB1/NCKAP1L	9
GO:0033673	negative regulation of kinase activity	14/319	237/18722	5.92415131175006e-05	0.00105887765402628	TNFAIP3/GADD45B/DUSP1/TRIB1/IL1B/CDKN1A/PRDX3/IRS2/DNAJA1/NPM1/MIDN/SNCA/HNRNPU/APOE	14
GO:0072593	reactive oxygen species metabolic process	14/319	239/18722	6.48577353378708e-05	0.00115231198434938	DDIT4/HIF1A/SOD2/CDKN1A/TNF/PRDX3/GRB2/PMAIP1/SNCA/NCF2/HBG1/PAGE4/THBS1/DCXR	14
GO:0048145	regulation of fibroblast proliferation	8/319	80/18722	6.50295257526284e-05	0.00115231198434938	FN1/CDKN1A/FOSL2/CTNNB1/FTH1/S100A6/ZMIZ1/EREG	8
GO:0031396	regulation of protein ubiquitination	13/319	210/18722	6.74227215303944e-05	0.00118959145155129	TNFAIP3/BIRC3/GABARAP/DNAJA1/NPM1/RIPK2/NMI/HSP90AB1/RPL23/RPS15/ISG15/RPS20/RPL5	13
GO:0034114	regulation of heterotypic cell-cell adhesion	5/319	26/18722	6.82202160619805e-05	0.00119851841124274	KLF4/IL1B/TNF/MYADM/IL1RN	5
GO:0007162	negative regulation of cell adhesion	16/319	303/18722	6.85708349370664e-05	0.00119955192521821	KLF4/DUSP1/VEGFA/MYADM/BCL6/PRNP/SEMA4D/CEBPB/RGCC/IL1RN/GBP1/FBLN1/HMGB1/THBS1/HLA-DRB1/NCKAP1L	16
GO:0031663	lipopolysaccharide-mediated signaling pathway	7/319	60/18722	6.95212214473927e-05	0.00121102432783996	NFKBIA/TNFAIP3/CCL3/TRIB1/IL1B/TNF/RIPK2	7
GO:0048144	fibroblast proliferation	8/319	81/18722	7.11022858243686e-05	0.00123333964989021	FN1/CDKN1A/FOSL2/CTNNB1/FTH1/S100A6/ZMIZ1/EREG	8
GO:0045621	positive regulation of lymphocyte differentiation	9/319	104/18722	7.19331168991589e-05	0.00123570395994551	CD83/NFKBIZ/NLRP3/BCL6/RIPK2/ZMIZ1/HLA-DRA/HLA-DRB1/NCKAP1L	9
GO:0048661	positive regulation of smooth muscle cell proliferation	9/319	104/18722	7.19331168991589e-05	0.00123570395994551	JUN/TNF/HBEGF/ID2/PTGS2/HMOX1/EREG/NR4A3/THBS1	9
GO:0034614	cellular response to reactive oxygen species	11/319	155/18722	7.24670346914717e-05	0.00123570395994551	FOS/TNFAIP3/KLF4/JUN/KDM6B/SOD2/PPIF/PRDX3/KLF2/NR4A3/STAT6	11
GO:0030890	positive regulation of B cell proliferation	6/319	42/18722	7.30420973648163e-05	0.00123570395994551	CDKN1A/GPR183/IRS2/BCL6/CD81/NCKAP1L	6
GO:0046688	response to copper ion	6/319	42/18722	7.30420973648163e-05	0.00123570395994551	ICAM1/PRNP/SNCA/IL1A/MT2A/AOC1	6
GO:1902895	positive regulation of pri-miRNA transcription by RNA polymerase II	6/319	42/18722	7.30420973648163e-05	0.00123570395994551	FOS/KLF4/JUN/HIF1A/TNF/EGR1	6
GO:0001666	response to hypoxia	16/319	307/18722	7.99945067802325e-05	0.00134777630071121	NR4A2/DDIT4/CXCR4/HIF1A/ICAM1/SOD2/VEGFA/BNIP3L/LDHA/PGK1/PMAIP1/PTGS2/HMOX1/EGR1/RGCC/THBS1	16
GO:0007369	gastrulation	12/319	185/18722	8.20396099956056e-05	0.00137099527110543	KLF4/DUSP2/DUSP1/FN1/KDM6B/MYADM/CTNNB1/SYF2/ETS2/IL1RN/NR4A3/RPS6	12
GO:0043433	negative regulation of DNA-binding transcription factor activity	12/319	185/18722	8.20396099956056e-05	0.00137099527110543	NFKBIA/TNFAIP3/KLF4/TRIB1/TMSB4X/BHLHE40/NLRP3/PIM1/ID2/PRNP/HMOX1/HES1	12
GO:0042116	macrophage activation	9/319	106/18722	8.34620400553012e-05	0.00138911921727669	JUND/CCL3/TNF/SNCA/IFNGR2/NMI/C5AR1/HMGB1/THBS1	9
GO:0031669	cellular response to nutrient levels	13/319	215/18722	8.56342311517998e-05	0.00140283680117274	ATF3/JUN/ICAM1/HNRNPA1/CDKN1A/GABARAPL1/PIM1/KLF10/MAP1LC3B/GABARAP/PMAIP1/HMOX1/AOC1	13
GO:0002260	lymphocyte homeostasis	7/319	62/18722	8.59924285807661e-05	0.00140283680117274	TNFAIP3/HIF1A/PMAIP1/SKIL/TSC22D3/RPS6/NCKAP1L	7
GO:0010573	vascular endothelial growth factor production	7/319	62/18722	8.59924285807661e-05	0.00140283680117274	IL1B/HIF1A/TNF/PTGS2/IL1A/C5AR1/C3	7
GO:0032731	positive regulation of interleukin-1 beta production	7/319	62/18722	8.59924285807661e-05	0.00140283680117274	CCL3/TNF/NLRP3/RIPK2/EGR1/MNDA/HMGB1	7
GO:0045428	regulation of nitric oxide biosynthetic process	7/319	62/18722	8.59924285807661e-05	0.00140283680117274	KLF4/IL1B/ICAM1/TNF/PTGS2/KLF2/HSP90AB1	7
GO:0048569	post-embryonic animal organ development	4/319	15/18722	9.73300458017395e-05	0.00158151706834368	KLF4/VEGFA/LDHA/HMGN1	4
GO:0002709	regulation of T cell mediated immunity	8/319	85/18722	0.000100307025872633	0.0016198176402898	IL1B/NLRP3/CD81/HLA-A/HLA-DRA/HMGB1/HLA-DRB1/NCKAP1L	8
GO:0046883	regulation of hormone secretion	14/319	249/18722	0.000100475188098735	0.0016198176402898	IL1B/PIM3/HIF1A/TNF/OSM/IRS2/HCAR2/MIDN/FFAR2/SERP1/SPP1/RETN/HLA-DRB1/PPP3CA	14
GO:0070482	response to oxygen levels	17/319	347/18722	0.000102656283462336	0.0016485155520065	NR4A2/DDIT4/CXCR4/HIF1A/ICAM1/SOD2/VEGFA/CDKN1A/BNIP3L/LDHA/PGK1/PMAIP1/PTGS2/HMOX1/EGR1/RGCC/THBS1	17
GO:0002456	T cell mediated immunity	9/319	109/18722	0.000103640820282559	0.0016578498528467	IL1B/ICAM1/NLRP3/CD81/HLA-A/HLA-DRA/HMGB1/HLA-DRB1/NCKAP1L	9
GO:0030888	regulation of B cell proliferation	7/319	64/18722	0.000105511889082146	0.00167474662554711	CDKN1A/GPR183/IRS2/BCL6/CD81/MNDA/NCKAP1L	7
GO:0080164	regulation of nitric oxide metabolic process	7/319	64/18722	0.000105511889082146	0.00167474662554711	KLF4/IL1B/ICAM1/TNF/PTGS2/KLF2/HSP90AB1	7
GO:0009408	response to heat	9/319	110/18722	0.000111214252948547	0.00175846843796722	IER5/DNAJB6/CDKN1A/DNAJA1/PTGS2/HMOX1/HSP90AB1/IL1A/THBS1	9
GO:0009896	positive regulation of catabolic process	21/319	492/18722	0.000116104887626337	0.00182469333754911	TNFAIP3/TRIB1/IL1B/HIF1A/BNIP3L/TNF/GABARAP/ZFP36/IRS2/SNCA/RIPK2/OAZ1/HMOX1/CD81/TOB1/TRIM22/SUMO2/RNF19B/APOE/HMGB1/PIAS1	21
GO:0032102	negative regulation of response to external stimulus	19/319	420/18722	0.000116290356224244	0.00182469333754911	TNFAIP3/KLF4/DUSP1/SOCS3/TRIB1/METRNL/TNF/NLRP3/ZFP36/SEMA4D/NMI/SERPINB9/PTGER4/SPP1/ISG15/APOE/HLA-A/THBS1/HLA-DRB1	19
GO:0050920	regulation of chemotaxis	13/319	223/18722	0.000123637744567305	0.0019326036802897	CXCL8/CCL3/DUSP1/TMSB4X/CCL4/CXCR4/VEGFA/GPR183/SEMA4D/C5AR1/HMGB1/THBS1/NCKAP1L	13
GO:0032635	interleukin-6 production	11/319	165/18722	0.000126859871909546	0.00195672146533429	TNFAIP3/IL1B/TNF/AKIRIN2/RIPK2/KLF2/CEBPB/EREG/IL1A/HMGB1/NCKAP1L	11
GO:0032675	regulation of interleukin-6 production	11/319	165/18722	0.000126859871909546	0.00195672146533429	TNFAIP3/IL1B/TNF/AKIRIN2/RIPK2/KLF2/CEBPB/EREG/IL1A/HMGB1/NCKAP1L	11
GO:1901222	regulation of NIK/NF-kappaB signaling	9/319	112/18722	0.000127756665171179	0.00195672146533429	NFKBIA/IL1B/TMSB4X/TNF/NLRP3/LITAF/LIMS1/NMI/HMGB1	9
GO:0002399	MHC class II protein complex assembly	4/319	16/18722	0.000128036505515671	0.00195672146533429	HLA-DPB1/HLA-DQA1/HLA-DRA/HLA-DRB1	4
GO:0002503	peptide antigen assembly with MHC class II protein complex	4/319	16/18722	0.000128036505515671	0.00195672146533429	HLA-DPB1/HLA-DQA1/HLA-DRA/HLA-DRB1	4
GO:0090336	positive regulation of brown fat cell differentiation	4/319	16/18722	0.000128036505515671	0.00195672146533429	METRNL/PIM1/PTGS2/HNRNPU	4
GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	16/319	320/18722	0.00012947425526637	0.00196409100885627	SRSF5/NCL/HNRNPA1/SRSF3/HNRNPF/HNRNPM/RNU11/SYF2/LSM6/SRSF7/YTHDC1/DDX5/NPM1/FRG1/BCAS2/HNRNPU	16
GO:0000398	mRNA splicing, via spliceosome	16/319	320/18722	0.00012947425526637	0.00196409100885627	SRSF5/NCL/HNRNPA1/SRSF3/HNRNPF/HNRNPM/RNU11/SYF2/LSM6/SRSF7/YTHDC1/DDX5/NPM1/FRG1/BCAS2/HNRNPU	16
GO:0060538	skeletal muscle organ development	11/319	166/18722	0.000133837647623333	0.00201970927587596	FOS/ATF3/NR4A1/CTNNB1/DDX5/BASP1/YBX3/EGR1/MAFF/VAMP5/PPP3CA	11
GO:1903311	regulation of mRNA metabolic process	15/319	288/18722	0.000134123238217985	0.00201970927587596	NCL/HNRNPA1/SRSF3/HNRNPM/HNRNPA0/ZFP36/SRSF7/YTHDC1/DDX5/NPM1/YBX3/HNRNPU/SERBP1/TOB1/YBX1	15
GO:0002708	positive regulation of lymphocyte mediated immunity	9/319	113/18722	0.000136769700118992	0.00205204466127436	IL1B/TNF/NLRP3/CD81/C3/HLA-A/HLA-DRA/STAT6/HLA-DRB1	9
GO:0045598	regulation of fat cell differentiation	10/319	139/18722	0.000137281804497362	0.00205223817559511	METRNL/TNF/PIM1/ZFP36/ID2/PTGS2/CEBPB/HNRNPU/HES1/ADIRF	10
GO:0036293	response to decreased oxygen levels	16/319	322/18722	0.000139080639439891	0.00207159604614997	NR4A2/DDIT4/CXCR4/HIF1A/ICAM1/SOD2/VEGFA/BNIP3L/LDHA/PGK1/PMAIP1/PTGS2/HMOX1/EGR1/RGCC/THBS1	16
GO:0009410	response to xenobiotic stimulus	20/319	462/18722	0.000139674958798	0.00207293774591545	FOS/FOSB/JUN/IL1B/CXCR4/PLIN2/ICAM1/SOD2/CDKN1A/PDE4B/LDHA/PRNP/SNCA/TGIF1/PTGS2/HMOX1/HSP90AB1/ADIRF/DAD1/NCKAP1L	20
GO:0042176	regulation of protein catabolic process	18/319	391/18722	0.000141264748218331	0.00208899057527179	TNFAIP3/TRIB1/IL1B/TNF/GABARAP/SNX3/SNCA/OAZ1/HSP90AB1/EEF1A1/CD81/SUMO2/RNF19B/RPL23/APOE/TIMP3/RPL5/PIAS1	18
GO:0071674	mononuclear cell migration	12/319	196/18722	0.000141905046863766	0.00209093780522202	CCL3/DUSP1/CCL4/CXCR4/ICAM1/CCL3L3/TNF/GPR183/CCL20/C5AR1/HMGB1/THBS1	12
GO:0010952	positive regulation of peptidase activity	12/319	197/18722	0.000148847388742701	0.00216885728699088	FN1/CYCS/ANP32B/TNF/NLRP3/AKIRIN2/PMAIP1/SNCA/RIPK2/S100A8/FBLN1/HMGB1	12
GO:0042594	response to starvation	12/319	197/18722	0.000148847388742701	0.00216885728699088	ATF3/JUN/HNRNPA1/CDKN1A/GABARAPL1/KLF10/MAP1LC3B/GABARAP/ZFP36/PMAIP1/PAGE4/AOC1	12
GO:0071248	cellular response to metal ion	12/319	197/18722	0.000148847388742701	0.00216885728699088	FOS/FOSB/JUND/JUN/JUNB/PPIF/PRNP/SNCA/PTGS2/HMOX1/MT2A/AOC1	12
GO:0000375	RNA splicing, via transesterification reactions	16/319	324/18722	0.000149303481444519	0.00216885728699088	SRSF5/NCL/HNRNPA1/SRSF3/HNRNPF/HNRNPM/RNU11/SYF2/LSM6/SRSF7/YTHDC1/DDX5/NPM1/FRG1/BCAS2/HNRNPU	16
GO:0050921	positive regulation of chemotaxis	10/319	141/18722	0.000154446459753278	0.00223566688748495	CXCL8/CCL3/TMSB4X/CCL4/CXCR4/VEGFA/C5AR1/HMGB1/THBS1/NCKAP1L	10
GO:0048146	positive regulation of fibroblast proliferation	6/319	48/18722	0.000156832829992403	0.00226224478631146	FN1/CDKN1A/FOSL2/S100A6/ZMIZ1/EREG	6
GO:0001649	osteoblast differentiation	13/319	229/18722	0.000160962695591852	0.00230849075268851	JUND/CCL3/JUNB/TNF/AREG/CTNNB1/DDX5/SEMA4D/CEBPB/HNRNPU/TOB1/SPP1/RPS15	13
GO:0033674	positive regulation of kinase activity	20/319	467/18722	0.000161161966923279	0.00230849075268851	IL1B/VEGFA/CDKN1A/TNF/HBEGF/AREG/PRNP/NPM1/SNCA/ERP29/HSP90AB1/CD81/EGR1/EREG/RGCC/HMGB1/THBS1/DGKZ/HLA-DRB1/NCKAP1L	20
GO:0090713	immunological memory process	4/319	17/18722	0.000165192662773247	0.00235801054396117	BCL6/CD81/HLA-DRA/HLA-DRB1	4
GO:0031330	negative regulation of cellular catabolic process	14/319	262/18722	0.00017135053323567	0.00243744651256691	MCL1/HNRNPA0/ZFP36/SNCA/HMOX1/HSP90AB1/YBX3/HNRNPU/TOB1/RPL23/YBX1/TIMP3/RPL5/APOC1	14
GO:0038061	NIK/NF-kappaB signaling	10/319	143/18722	0.000173385406400615	0.00244944125674546	NFKBIA/IL1B/TMSB4X/BIRC3/TNF/NLRP3/LITAF/LIMS1/NMI/HMGB1	10
GO:0062013	positive regulation of small molecule metabolic process	10/319	143/18722	0.000173385406400615	0.00244944125674546	IL1B/TMSB4X/HIF1A/TNF/IRS2/PMAIP1/SNCA/PTGS2/NR4A3/HMGB1	10
GO:0046879	hormone secretion	15/319	295/18722	0.00017439889213244	0.00245273794358476	IL1B/PIM3/HIF1A/TNF/OSM/IRS2/HCAR2/MIDN/FFAR2/SERP1/IL1RN/SPP1/RETN/HLA-DRB1/PPP3CA	15
GO:1903312	negative regulation of mRNA metabolic process	8/319	92/18722	0.000175052046123648	0.00245273794358476	HNRNPA0/ZFP36/SRSF7/NPM1/YBX3/HNRNPU/TOB1/YBX1	8
GO:0051051	negative regulation of transport	20/319	470/18722	0.00017540864884795	0.00245273794358476	IL1B/PIM3/ICAM1/PPIF/TNF/OSM/IRS2/MIDN/SNX3/SNCA/PTGS2/OAZ1/ERP29/HMOX1/APOE/HMGB1/THBS1/APOC1/PPP3CA/NCKAP1L	20
GO:0006953	acute-phase response	6/319	49/18722	0.000176184265700035	0.00245523225861982	IL1B/FN1/TNF/PTGS2/CEBPB/IL1A	6
GO:0050767	regulation of neurogenesis	17/319	364/18722	0.000181901352852548	0.002526339397219	IL1B/FN1/CXCR4/BHLHE40/HIF1A/YWHAH/VEGFA/TNF/CTNNB1/ID2/HMGB2/SKIL/SEMA4D/HES1/SPP1/NAP1L1/PPP3CA	17
GO:0006402	mRNA catabolic process	13/319	232/18722	0.000183008323865174	0.00253315562090818	HNRNPM/HNRNPA0/ZFP36/ETF1/LSM6/DDX5/NPM1/YBX3/HNRNPU/SERBP1/TOB1/SSB/YBX1	13
GO:0019722	calcium-mediated signaling	12/319	202/18722	0.000188088524959123	0.00259473800707031	CXCL8/CCL3/CCL4/CXCR4/TNF/CCRL2/PRNP/PLEK/CCL20/DEFB1/GBP1/PPP3CA	12
GO:1901796	regulation of signal transduction by p53 class mediator	8/319	93/18722	0.000188736650785371	0.00259497114173465	SGK1/PMAIP1/DDX5/NPM1/RPL23/RPS15/RPS20/RPL5	8
GO:0045446	endothelial cell differentiation	9/319	118/18722	0.000190199850227171	0.002606371947613	IL1B/CXCR4/ICAM1/KDM6B/VEGFA/TNF/MYADM/CTNNB1/BTG1	9
GO:0035767	endothelial cell chemotaxis	5/319	32/18722	0.000192072541228099	0.00261577838938294	TMSB4X/NR4A1/VEGFA/HMGB1/THBS1	5
GO:0051607	defense response to virus	14/319	265/18722	0.000192795147648512	0.00261577838938294	TNFAIP3/DDIT4/BIRC3/BNIP3L/PMAIP1/IFNGR2/MX2/TRIM22/ISG15/IFI44L/GBP1/IFIT3/IFIT1/HERC5	14
GO:0140546	defense response to symbiont	14/319	265/18722	0.000192795147648512	0.00261577838938294	TNFAIP3/DDIT4/BIRC3/BNIP3L/PMAIP1/IFNGR2/MX2/TRIM22/ISG15/IFI44L/GBP1/IFIT3/IFIT1/HERC5	14
GO:0043524	negative regulation of neuron apoptotic process	10/319	145/18722	0.000194242186870705	0.00262349858340514	NR4A2/HIF1A/SOD2/SNCA/HMOX1/HSP90AB1/CEBPB/SET/C5AR1/APOE	10
GO:0010720	positive regulation of cell development	15/319	298/18722	0.000194640493295687	0.00262349858340514	TRIB1/IL1B/FN1/CXCR4/HIF1A/VEGFA/TNF/MYADM/CTNNB1/ID2/LIMS1/SKIL/SEMA4D/HES1/NAP1L1	15
GO:0045619	regulation of lymphocyte differentiation	11/319	174/18722	0.000202385138723819	0.00271336767427179	CD83/NFKBIZ/NLRP3/BCL6/ID2/RIPK2/ZMIZ1/HLA-DRA/HMGB1/HLA-DRB1/NCKAP1L	11
GO:0002690	positive regulation of leukocyte chemotaxis	8/319	94/18722	0.000203288067058066	0.00271336767427179	CXCL8/CCL3/CCL4/VEGFA/C5AR1/HMGB1/THBS1/NCKAP1L	8
GO:0051702	biological process involved in interaction with symbiont	8/319	94/18722	0.000203288067058066	0.00271336767427179	CCL3/JUN/CCL4/FN1/TREM1/CHD1/APOE/PF4	8
GO:0045580	regulation of T cell differentiation	10/319	146/18722	0.000205436828921378	0.00273317412199283	CD83/NFKBIZ/NLRP3/BCL6/RIPK2/ZMIZ1/HLA-DRA/HMGB1/HLA-DRB1/NCKAP1L	10
GO:0002501	peptide antigen assembly with MHC protein complex	4/319	18/18722	0.000209551044578859	0.00273480744210696	HLA-DPB1/HLA-DQA1/HLA-DRA/HLA-DRB1	4
GO:0002544	chronic inflammatory response	4/319	18/18722	0.000209551044578859	0.00273480744210696	TNFAIP3/TNF/S100A8/THBS1	4
GO:0031649	heat generation	4/319	18/18722	0.000209551044578859	0.00273480744210696	IL1B/TNF/PTGS2/IL1A	4
GO:0060749	mammary gland alveolus development	4/319	18/18722	0.000209551044578859	0.00273480744210696	HIF1A/VEGFA/AREG/ID2	4
GO:0061377	mammary gland lobule development	4/319	18/18722	0.000209551044578859	0.00273480744210696	HIF1A/VEGFA/AREG/ID2	4
GO:1901673	regulation of mitotic spindle assembly	4/319	18/18722	0.000209551044578859	0.00273480744210696	CHMP1B/CHMP2B/CHMP5/HNRNPU	4
GO:0062012	regulation of small molecule metabolic process	16/319	334/18722	0.000210866860574521	0.00274327108804384	IL1B/TMSB4X/DDIT4/HIF1A/TNF/IRS2/PMAIP1/MIDN/SNCA/PTGS2/PLEK/EGR1/APOE/NR4A3/HMGB1/APOC1	16
GO:0006913	nucleocytoplasmic transport	15/319	301/18722	0.000216886797976922	0.00279868163747242	NFKBIA/IL1B/HNRNPA1/CDKN1A/ANP32B/SRSF3/YTHDC1/NPM1/PTGS2/HSP90AB1/MX2/SSB/RPL23/RPS15/PPP3CA	15
GO:0051169	nuclear transport	15/319	301/18722	0.000216886797976922	0.00279868163747242	NFKBIA/IL1B/HNRNPA1/CDKN1A/ANP32B/SRSF3/YTHDC1/NPM1/PTGS2/HSP90AB1/MX2/SSB/RPL23/RPS15/PPP3CA	15
GO:1903531	negative regulation of secretion by cell	10/319	147/18722	0.000217168436476211	0.00279868163747242	IL1B/PIM3/OSM/MIDN/SNCA/ERP29/HMOX1/APOE/PPP3CA/NCKAP1L	10
GO:1903321	negative regulation of protein modification by small protein conjugation or removal	8/319	95/18722	0.000218747799802184	0.00281022564058368	TNFAIP3/CTNNB1/DNAJA1/RPL23/RPS15/ISG15/RPS20/RPL5	8
GO:0032729	positive regulation of interferon-gamma production	7/319	72/18722	0.00022278536634276	0.00282379682738178	IL1B/TNF/PDE4B/RIPK2/HLA-DPB1/ISG15/HLA-A	7
GO:0001975	response to amphetamine	5/319	33/18722	0.000223238620505735	0.00282379682738178	NR4A2/NR4A1/ICAM1/RGS10/PPP3CA	5
GO:0046685	response to arsenic-containing substance	5/319	33/18722	0.000223238620505735	0.00282379682738178	ATF3/HNRNPA1/CDKN1A/PPIF/HMOX1	5
GO:1901099	negative regulation of signal transduction in absence of ligand	5/319	33/18722	0.000223238620505735	0.00282379682738178	IL1B/MCL1/TNF/IL1A/PF4	5
GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	5/319	33/18722	0.000223238620505735	0.00282379682738178	IL1B/MCL1/TNF/IL1A/PF4	5
GO:0043484	regulation of RNA splicing	10/319	148/18722	0.000229457262781122	0.00288470583270089	SRSF5/NCL/HNRNPA1/SRSF3/HNRNPF/SRSF7/YTHDC1/DDX5/NPM1/HNRNPU	10
GO:1903900	regulation of viral life cycle	10/319	148/18722	0.000229457262781122	0.00288470583270089	CXCL8/TNF/CHMP2B/DDX5/SNX3/TRIM22/FCN1/ISG15/IFIT1/HLA-DRB1	10
GO:0043410	positive regulation of MAPK cascade	20/319	480/18722	0.000231234050426251	0.00289818043079974	CCL3/GADD45B/IL1B/CCL4/ICAM1/CCL3L3/VEGFA/TNF/OSM/GPR183/CTNNB1/RIPK2/ERP29/CD81/CCL20/C5AR1/APOE/HMGB1/THBS1/HLA-DRB1	20
GO:0050679	positive regulation of epithelial cell proliferation	12/319	207/18722	0.000235841227879324	0.00294694008453466	TNFAIP3/NR4A1/HIF1A/VEGFA/AREG/CTNNB1/HMGB2/HMOX1/LRG1/C5AR1/NR4A3/HMGB1	12
GO:0032732	positive regulation of interleukin-1 production	7/319	73/18722	0.000242868614426856	0.00302555416336002	CCL3/TNF/NLRP3/RIPK2/EGR1/MNDA/HMGB1	7
GO:0002688	regulation of leukocyte chemotaxis	9/319	122/18722	0.000244537884083444	0.00303714574461341	CXCL8/CCL3/DUSP1/CCL4/VEGFA/C5AR1/HMGB1/THBS1/NCKAP1L	9
GO:1901215	negative regulation of neuron death	12/319	208/18722	0.000246537168348225	0.00305275391289022	NR4A2/HIF1A/SOD2/CTNNB1/SNCA/HMOX1/HSP90AB1/CEBPB/SET/C5AR1/APOE/NR4A3	12
GO:0032743	positive regulation of interleukin-2 production	5/319	34/18722	0.00025810761281723	0.00316649337834611	CD83/IL1B/PDE4B/RIPK2/IL1A	5
GO:0050869	negative regulation of B cell activation	5/319	34/18722	0.00025810761281723	0.00316649337834611	TNFAIP3/SAMSN1/BCL6/ID2/MNDA	5
GO:0001936	regulation of endothelial cell proliferation	11/319	179/18722	0.00025878587527179	0.00316649337834611	NR4A1/HIF1A/VEGFA/TNF/HMGB2/HMOX1/LRG1/RGCC/APOE/HMGB1/THBS1	11
GO:0009914	hormone transport	15/319	306/18722	0.000258864278263693	0.00316649337834611	IL1B/PIM3/HIF1A/TNF/OSM/IRS2/HCAR2/MIDN/FFAR2/SERP1/IL1RN/SPP1/RETN/HLA-DRB1/PPP3CA	15
GO:0002396	MHC protein complex assembly	4/319	19/18722	0.000261884638442636	0.00316649337834611	HLA-DPB1/HLA-DQA1/HLA-DRA/HLA-DRB1	4
GO:0002483	antigen processing and presentation of endogenous peptide antigen	4/319	19/18722	0.000261884638442636	0.00316649337834611	HLA-C/HLA-A/HLA-DRA/HLA-DRB1	4
GO:0051444	negative regulation of ubiquitin-protein transferase activity	4/319	19/18722	0.000261884638442636	0.00316649337834611	RPL23/RPS15/RPS20/RPL5	4
GO:0070262	peptidyl-serine dephosphorylation	4/319	19/18722	0.000261884638442636	0.00316649337834611	PPP1R15A/DUSP1/PPP1R15B/PPP3CA	4
GO:0050866	negative regulation of cell activation	12/319	210/18722	0.000269171586692897	0.00324405495545965	TNFAIP3/SAMSN1/BCL6/ID2/PRNP/HMOX1/CEBPB/MNDA/APOE/HMGB1/HLA-DRB1/NCKAP1L	12
GO:0071456	cellular response to hypoxia	10/319	151/18722	0.000269877595418925	0.00324405495545965	HIF1A/ICAM1/VEGFA/BNIP3L/PGK1/PMAIP1/PTGS2/HMOX1/EGR1/RGCC	10
GO:0010721	negative regulation of cell development	11/319	180/18722	0.0002715275018301	0.00325437189511237	IL1B/YWHAH/VEGFA/TNF/CTNNB1/SEMA4D/HES1/SPP1/GBP1/FBLN1/PPP3CA	11
GO:0007566	embryo implantation	6/319	53/18722	0.000273208645746124	0.00326500215890208	IL1B/VEGFA/VMP1/PTGS2/SPP1/FBLN1	6
GO:0001909	leukocyte mediated cytotoxicity	9/319	124/18722	0.000276193635992926	0.00329110735526643	ICAM1/TREM1/SERPINB9/RNF19B/HLA-A/HLA-DRA/HLA-DRB1/TUBB/NCKAP1L	9
GO:0002440	production of molecular mediator of immune response	15/319	308/18722	0.000277521416859207	0.00329737151649769	IL1B/TNF/NLRP3/TREM1/BCL6/FFAR2/HMOX1/CD81/HLA-DPB1/HLA-DQA1/NR4A3/HLA-A/HLA-DRA/STAT6/HLA-DRB1	15
GO:0043434	response to peptide hormone	18/319	414/18722	0.000284250954552225	0.00336434004379709	JUND/SOCS3/NR4A2/IL1B/SRSF5/NR4A1/ICAM1/AREG/GRB2/IRS2/BTG1/PTGS2/EGR1/EREG/NR4A3/STAT6/CSH1/RETN	18
GO:1905952	regulation of lipid localization	11/319	181/18722	0.000284794535451566	0.00336434004379709	NFKBIA/IL1B/PLIN2/TNF/IRS2/SPP1/APOE/C3/THBS1/RETN/APOC1	11
GO:0048662	negative regulation of smooth muscle cell proliferation	7/319	75/18722	0.000287406640869012	0.0033854690561963	TNFAIP3/KLF4/TRIB1/SOD2/CDKN1A/HMOX1/APOE	7
GO:1902893	regulation of pri-miRNA transcription by RNA polymerase II	6/319	54/18722	0.000303011336782744	0.00355908458718246	FOS/KLF4/JUN/HIF1A/TNF/EGR1	6
GO:2001235	positive regulation of apoptotic signaling pathway	9/319	126/18722	0.000311170103570129	0.00362339642318649	ATF3/G0S2/MCL1/TNF/PMAIP1/SKIL/TIMP3/S100A8/THBS1	9
GO:0006809	nitric oxide biosynthetic process	7/319	76/18722	0.000312012243689618	0.00362339642318649	KLF4/IL1B/ICAM1/TNF/PTGS2/KLF2/HSP90AB1	7
GO:0031100	animal organ regeneration	7/319	76/18722	0.000312012243689618	0.00362339642318649	SRSF5/CDKN1A/HMOX1/CEBPB/RPS15/C5AR1/NR4A3	7
GO:0043536	positive regulation of blood vessel endothelial cell migration	7/319	76/18722	0.000312012243689618	0.00362339642318649	TMSB4X/HIF1A/VEGFA/PTGS2/HMOX1/HMGB1/THBS1	7
GO:0019932	second-messenger-mediated signaling	15/319	312/18722	0.000318339303660892	0.00368645880943641	CXCL8/CCL3/CCL4/CXCR4/VEGFA/TNF/CCRL2/PRNP/PLEK/CCL20/APOE/DEFB1/GBP1/THBS1/PPP3CA	15
GO:0032495	response to muramyl dipeptide	4/319	20/18722	0.000322984102283249	0.00371929312181075	NFKBIA/TNFAIP3/CHMP5/RIPK2	4
GO:0071243	cellular response to arsenic-containing substance	4/319	20/18722	0.000322984102283249	0.00371929312181075	ATF3/HNRNPA1/PPIF/HMOX1	4
GO:0007519	skeletal muscle tissue development	10/319	155/18722	0.000332895557447692	0.00380344709636798	FOS/ATF3/NR4A1/CTNNB1/DDX5/YBX3/EGR1/MAFF/VAMP5/PPP3CA	10
GO:0048024	regulation of mRNA splicing, via spliceosome	8/319	101/18722	0.000333067612428235	0.00380344709636798	NCL/HNRNPA1/SRSF3/SRSF7/YTHDC1/DDX5/NPM1/HNRNPU	8
GO:0050830	defense response to Gram-positive bacterium	8/319	101/18722	0.000333067612428235	0.00380344709636798	RPL39/TNF/HMGB2/RIPK2/GBP4/C5AR1/DEFB1/HLA-A	8
GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	5/319	36/18722	0.000340092339601753	0.00387290750166983	HLA-DPB1/HLA-DQA1/HLA-DRA/THBS1/HLA-DRB1	5
GO:0009612	response to mechanical stimulus	12/319	216/18722	0.000347959805896218	0.00395155459126893	NFKBIA/FOS/FOSB/JUND/JUN/IL1B/CXCR4/CTNNB1/PTGS2/PTGER4/THBS1/RETN	12
GO:0009267	cellular response to starvation	10/319	156/18722	0.000350436266986427	0.00396871485835042	ATF3/JUN/HNRNPA1/CDKN1A/GABARAPL1/KLF10/MAP1LC3B/GABARAP/PMAIP1/AOC1	10
GO:0045860	positive regulation of protein kinase activity	17/319	386/18722	0.000360298859255777	0.00406919947912225	IL1B/VEGFA/CDKN1A/TNF/HBEGF/AREG/PRNP/NPM1/SNCA/ERP29/HSP90AB1/EGR1/EREG/RGCC/HMGB1/THBS1/NCKAP1L	17
GO:0070374	positive regulation of ERK1 and ERK2 cascade	12/319	217/18722	0.00036282391097897	0.0040864906795467	CCL3/CCL4/ICAM1/CCL3L3/TNF/GPR183/RIPK2/CCL20/C5AR1/APOE/HMGB1/HLA-DRB1	12
GO:0051250	negative regulation of lymphocyte activation	10/319	157/18722	0.000368741088143525	0.00413592545927548	TNFAIP3/SAMSN1/BCL6/ID2/PRNP/CEBPB/MNDA/HMGB1/HLA-DRB1/NCKAP1L	10
GO:0002711	positive regulation of T cell mediated immunity	6/319	56/18722	0.000370231225739085	0.00413592545927548	IL1B/NLRP3/CD81/HLA-A/HLA-DRA/HLA-DRB1	6
GO:0043388	positive regulation of DNA binding	6/319	56/18722	0.000370231225739085	0.00413592545927548	KLF4/PLAUR/CTNNB1/HMGB2/HES1/HMGB1	6
GO:0002695	negative regulation of leukocyte activation	11/319	187/18722	0.0003764193181271	0.00419365804016398	TNFAIP3/SAMSN1/BCL6/ID2/PRNP/HMOX1/CEBPB/MNDA/HMGB1/HLA-DRB1/NCKAP1L	11
GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	7/319	79/18722	0.000396127791289052	0.00440130094591701	CXCL8/RPL39/CXCL2/PPBP/HMGN2/PF4/DEFB1	7
GO:0002478	antigen processing and presentation of exogenous peptide antigen	5/319	38/18722	0.000440389029456925	0.00487989029675854	HLA-DPB1/HLA-DQA1/HLA-A/HLA-DRA/HLA-DRB1	5
GO:0010574	regulation of vascular endothelial growth factor production	6/319	58/18722	0.000448579637425171	0.00494399702266723	IL1B/HIF1A/PTGS2/IL1A/C5AR1/C3	6
GO:0043525	positive regulation of neuron apoptotic process	6/319	58/18722	0.000448579637425171	0.00494399702266723	CCL3/JUN/MCL1/TNF/CTNNB1/PRNP	6
GO:0036294	cellular response to decreased oxygen levels	10/319	161/18722	0.000450126743234905	0.00494778353325854	HIF1A/ICAM1/VEGFA/BNIP3L/PGK1/PMAIP1/PTGS2/HMOX1/EGR1/RGCC	10
GO:0046209	nitric oxide metabolic process	7/319	81/18722	0.000461625893816191	0.00503705607031649	KLF4/IL1B/ICAM1/TNF/PTGS2/KLF2/HSP90AB1	7
GO:0019882	antigen processing and presentation	8/319	106/18722	0.000461924139749287	0.00503705607031649	ICAM1/HLA-DPB1/HLA-DQA1/HLA-C/HLA-A/HLA-DRA/THBS1/HLA-DRB1	8
GO:2000278	regulation of DNA biosynthetic process	8/319	106/18722	0.000461924139749287	0.00503705607031649	KLF4/DUSP1/HNRNPA1/CDKN1A/CTNNB1/HSP90AB1/HNRNPU/RGCC	8
GO:0002274	myeloid leukocyte activation	12/319	223/18722	0.000463766387114	0.00504376618366576	CXCL8/JUND/CCL3/TNF/SNCA/IFNGR2/NMI/HMOX1/C5AR1/NR4A3/HMGB1/THBS1	12
GO:0071900	regulation of protein serine/threonine kinase activity	16/319	359/18722	0.000469109503068614	0.00508841468895797	TNFAIP3/DUSP1/TRIB1/IL1B/VEGFA/CDKN1A/TNF/DNAJA1/CCNL1/SNCA/ERP29/HSP90AB1/RGCC/APOE/HERC5/THBS1	16
GO:0061042	vascular wound healing	4/319	22/18722	0.000474715842396673	0.0051356758634019	TNFAIP3/CXCR4/VEGFA/TNF	4
GO:0002705	positive regulation of leukocyte mediated immunity	9/319	134/18722	0.000489762286421945	0.00528428063863562	IL1B/TNF/NLRP3/CD81/C3/HLA-A/HLA-DRA/STAT6/HLA-DRB1	9
GO:0001935	endothelial cell proliferation	11/319	193/18722	0.000491630847523891	0.00528428063863562	NR4A1/HIF1A/VEGFA/TNF/HMGB2/HMOX1/LRG1/RGCC/APOE/HMGB1/THBS1	11
GO:0032768	regulation of monooxygenase activity	6/319	59/18722	0.000492308315397091	0.00528428063863562	IL1B/HIF1A/TNF/SNCA/IL1A/APOE	6
GO:0072331	signal transduction by p53 class mediator	10/319	163/18722	0.000496103617362013	0.00529812801962805	DDIT4/SGK1/CDKN1A/PMAIP1/DDX5/NPM1/RPL23/RPS15/RPS20/RPL5	10
GO:0001892	embryonic placenta development	7/319	82/18722	0.000497464708240434	0.00529812801962805	SOCS3/JUNB/HIF1A/DNAJB6/GRB2/CEBPB/HES1	7
GO:2001057	reactive nitrogen species metabolic process	7/319	82/18722	0.000497464708240434	0.00529812801962805	KLF4/IL1B/ICAM1/TNF/PTGS2/KLF2/HSP90AB1	7
GO:0050769	positive regulation of neurogenesis	12/319	225/18722	0.000502279820759888	0.00533558744998424	IL1B/FN1/CXCR4/HIF1A/VEGFA/TNF/CTNNB1/ID2/SKIL/SEMA4D/HES1/NAP1L1	12
GO:0031348	negative regulation of defense response	13/319	258/18722	0.000508969884006043	0.00539271956997124	TNFAIP3/KLF4/SOCS3/METRNL/NLRP3/ZFP36/NMI/SERPINB9/PTGER4/ISG15/APOE/HLA-A/HLA-DRB1	13
GO:0050777	negative regulation of immune response	11/319	194/18722	0.000513437424515146	0.00541215705687632	TNFAIP3/SAMSN1/BCL6/NMI/HMOX1/SERPINB9/ISG15/HLA-A/STAT6/HLA-DRB1/NCKAP1L	11
GO:1901654	response to ketone	11/319	194/18722	0.000513437424515146	0.00541215705687632	FOS/FOSB/KLF4/DUSP1/DDIT4/ICAM1/CDKN1A/KLF2/PTGER4/SPP1/THBS1	11
GO:0002700	regulation of production of molecular mediator of immune response	10/319	164/18722	0.00052051330934631	0.00547271154660532	IL1B/TNF/NLRP3/BCL6/FFAR2/HMOX1/CD81/NR4A3/HLA-A/STAT6	10
GO:0071241	cellular response to inorganic substance	12/319	226/18722	0.000522524977654915	0.00547984740596774	FOS/FOSB/JUND/JUN/JUNB/PPIF/PRNP/SNCA/PTGS2/HMOX1/MT2A/AOC1	12
GO:0031397	negative regulation of protein ubiquitination	7/319	83/18722	0.000535485666877025	0.00558577234793707	TNFAIP3/DNAJA1/RPL23/RPS15/ISG15/RPS20/RPL5	7
GO:0019062	virion attachment to host cell	3/319	10/18722	0.000538060289414517	0.00558577234793707	ICAM1/HSP90AB1/CD81	3
GO:1904896	ESCRT complex disassembly	3/319	10/18722	0.000538060289414517	0.00558577234793707	CHMP1B/CHMP2B/CHMP5	3
GO:1904903	ESCRT III complex disassembly	3/319	10/18722	0.000538060289414517	0.00558577234793707	CHMP1B/CHMP2B/CHMP5	3
GO:0003158	endothelium development	9/319	136/18722	0.000545571957687655	0.00564948694723916	IL1B/CXCR4/ICAM1/KDM6B/VEGFA/TNF/MYADM/CTNNB1/BTG1	9
GO:0051091	positive regulation of DNA-binding transcription factor activity	13/319	260/18722	0.000547287196204228	0.00565300920501402	IL1B/ICAM1/VEGFA/TNF/NLRP3/PRDX3/CTNNB1/NPM1/RIPK2/RGCC/TRIM22/S100A8/PPP3CA	13
GO:0022408	negative regulation of cell-cell adhesion	11/319	196/18722	0.000559482402867434	0.00576449162453138	KLF4/VEGFA/MYADM/BCL6/PRNP/CEBPB/RGCC/IL1RN/HMGB1/HLA-DRB1/NCKAP1L	11
GO:0090335	regulation of brown fat cell differentiation	4/319	23/18722	0.000566994574696313	0.0058127548543056	METRNL/PIM1/PTGS2/HNRNPU	4
GO:1904666	regulation of ubiquitin protein ligase activity	4/319	23/18722	0.000566994574696313	0.0058127548543056	RPL23/RPS15/RPS20/RPL5	4
GO:0010921	regulation of phosphatase activity	7/319	84/18722	0.000575783268708557	0.00588817168572358	PPP1R15A/PPP1R15B/TNF/SEMA4D/HSP90AB1/PLEK/NCKAP1L	7
GO:0009636	response to toxic substance	13/319	262/18722	0.000588017749046372	0.00599292834415291	FOS/CCL3/CCL4/KDM6B/SOD2/CDKN1A/PIM1/PRDX3/PTGS2/HBG1/APOE/MT2A/UBA52	13
GO:0042255	ribosome assembly	6/319	61/18722	0.000589672063727453	0.00599292834415291	SBDS/NPM1/RPL3/RPS15/RPS28/RPL5	6
GO:0032611	interleukin-1 beta production	8/319	110/18722	0.000591858162910747	0.00599292834415291	TNFAIP3/CCL3/TNF/NLRP3/RIPK2/EGR1/MNDA/HMGB1	8
GO:0032651	regulation of interleukin-1 beta production	8/319	110/18722	0.000591858162910747	0.00599292834415291	TNFAIP3/CCL3/TNF/NLRP3/RIPK2/EGR1/MNDA/HMGB1	8
GO:0031099	regeneration	11/319	198/18722	0.000608925435409926	0.00613552074747599	KLF4/SRSF5/CDKN1A/HMOX1/CEBPB/CD81/SPP1/RPS15/C5AR1/NR4A3/PPP3CA	11
GO:0050864	regulation of B cell activation	11/319	198/18722	0.000608925435409926	0.00613552074747599	TNFAIP3/CDKN1A/GPR183/SAMSN1/IRS2/BCL6/ID2/CD81/MNDA/STAT6/NCKAP1L	11
GO:0071634	regulation of transforming growth factor beta production	5/319	41/18722	0.000630654302686774	0.00633892381013527	FN1/HIF1A/PTGS2/HSP90AB1/THBS1	5
GO:0051960	regulation of nervous system development	18/319	443/18722	0.000632676480079929	0.00634373904782582	IL1B/FN1/CXCR4/BHLHE40/HIF1A/YWHAH/VEGFA/TNF/CTNNB1/ID2/HMGB2/SKIL/SEMA4D/HES1/SPP1/NAP1L1/TYMP/PPP3CA	18
GO:0048002	antigen processing and presentation of peptide antigen	6/319	62/18722	0.000643637738921742	0.00643794341777928	HLA-DPB1/HLA-DQA1/HLA-C/HLA-A/HLA-DRA/HLA-DRB1	6
GO:0030522	intracellular receptor signaling pathway	13/319	265/18722	0.000653901730686924	0.006524733045762	NFKBIA/TNFAIP3/NR4A2/BIRC3/NR4A1/YWHAH/PIM1/DNAJA1/DDX5/RIPK2/KLF2/ZMIZ1/NR4A3	13
GO:0002791	regulation of peptide secretion	11/319	200/18722	0.000661959489279391	0.0065891415506721	IL1B/PIM3/HIF1A/TNF/IRS2/MIDN/FFAR2/SERP1/S100A8/HLA-DRB1/PPP3CA	11
GO:0002726	positive regulation of T cell cytokine production	4/319	24/18722	0.000671327429222547	0.00665018569044311	IL1B/NLRP3/CD81/HLA-A	4
GO:0051043	regulation of membrane protein ectodomain proteolysis	4/319	24/18722	0.000671327429222547	0.00665018569044311	IL1B/TNF/APOE/TIMP3	4
GO:1902373	negative regulation of mRNA catabolic process	6/319	63/18722	0.000701352628687781	0.00693091503974872	HNRNPA0/ZFP36/YBX3/HNRNPU/TOB1/YBX1	6
GO:0019915	lipid storage	7/319	87/18722	0.000711313834759866	0.00701249682181729	NFKBIA/IL1B/PLIN2/TNF/FFAR2/APOE/C3	7
GO:0090087	regulation of peptide transport	11/319	202/18722	0.000718784709361677	0.0070331767666081	IL1B/PIM3/HIF1A/TNF/IRS2/MIDN/FFAR2/SERP1/S100A8/HLA-DRB1/PPP3CA	11
GO:0048469	cell maturation	10/319	171/18722	0.000720783200032494	0.0070331767666081	NR4A2/HIF1A/VEGFA/CDKN1A/CTNNB1/KLF2/EREG/HES1/DEFB1/C3	10
GO:0051048	negative regulation of secretion	10/319	171/18722	0.000720783200032494	0.0070331767666081	IL1B/PIM3/OSM/MIDN/SNCA/ERP29/HMOX1/APOE/PPP3CA/NCKAP1L	10
GO:0050708	regulation of protein secretion	13/319	268/18722	0.00072590808154717	0.0070331767666081	IL1B/PIM3/HIF1A/TNF/IRS2/HCAR2/MIDN/ERP29/SERP1/IL1A/APOE/HLA-DRB1/PPP3CA	13
GO:0003263	cardioblast proliferation	3/319	11/18722	0.000730519698210085	0.0070331767666081	PIM1/CTNNB1/HES1	3
GO:0003264	regulation of cardioblast proliferation	3/319	11/18722	0.000730519698210085	0.0070331767666081	PIM1/CTNNB1/HES1	3
GO:0031652	positive regulation of heat generation	3/319	11/18722	0.000730519698210085	0.0070331767666081	IL1B/TNF/PTGS2	3
GO:0033083	regulation of immature T cell proliferation	3/319	11/18722	0.000730519698210085	0.0070331767666081	IL1B/RIPK2/IL1A	3
GO:0034115	negative regulation of heterotypic cell-cell adhesion	3/319	11/18722	0.000730519698210085	0.0070331767666081	KLF4/MYADM/IL1RN	3
GO:0070587	regulation of cell-cell adhesion involved in gastrulation	3/319	11/18722	0.000730519698210085	0.0070331767666081	KLF4/MYADM/IL1RN	3
GO:0051222	positive regulation of protein transport	14/319	303/18722	0.000739523846625059	0.00710323021840097	IL1B/HIF1A/ANP32B/TNF/IRS2/PRNP/HCAR2/PTGS2/OAZ1/HSP90AB1/CD81/SERP1/IL1A/HLA-DRB1	14
GO:0051701	biological process involved in interaction with host	11/319	203/18722	0.00074868353158476	0.00717444754858962	CXCL8/CXCR4/ICAM1/CHMP2B/SNX3/SERPINB9/CD81/TRIM22/FCN1/IFIT1/HLA-DRB1	11
GO:0045670	regulation of osteoclast differentiation	6/319	64/18722	0.000762991325888361	0.0072945519551792	FOS/CCL3/TNF/KLF10/CTNNB1/CEBPB	6
GO:0001709	cell fate determination	5/319	43/18722	0.000787892227995664	0.00735091746448256	KLF4/MCL1/IFRD1/CTNNB1/HES1	5
GO:0034142	toll-like receptor 4 signaling pathway	5/319	43/18722	0.000787892227995664	0.00735091746448256	NFKBIA/TNFAIP3/RIPK2/NMI/HMGB1	5
GO:0042088	T-helper 1 type immune response	5/319	43/18722	0.000787892227995664	0.00735091746448256	IL1B/RIPK2/HMGB1/STAT6/HLA-DRB1	5
GO:0071604	transforming growth factor beta production	5/319	43/18722	0.000787892227995664	0.00735091746448256	FN1/HIF1A/PTGS2/HSP90AB1/THBS1	5
GO:2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand	5/319	43/18722	0.000787892227995664	0.00735091746448256	IL1B/MCL1/TNF/IL1A/PF4	5
GO:0051099	positive regulation of binding	10/319	173/18722	0.000788432549412221	0.00735091746448256	KLF4/PLAUR/MAPRE1/CTNNB1/HMGB2/RIPK2/HSP90AB1/HES1/APOE/HMGB1	10
GO:0033233	regulation of protein sumoylation	4/319	25/18722	0.000788556215479643	0.00735091746448256	CTNNB1/ZMIZ1/EGR1/PIAS1	4
GO:0033622	integrin activation	4/319	25/18722	0.000788556215479643	0.00735091746448256	FN1/TLN1/PTGER4/PLEK	4
GO:0050995	negative regulation of lipid catabolic process	4/319	25/18722	0.000788556215479643	0.00735091746448256	IL1B/TNF/HCAR2/APOC1	4
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	4/319	25/18722	0.000788556215479643	0.00735091746448256	NFKBIA/TNFAIP3/BIRC3/RIPK2	4
GO:0090169	regulation of spindle assembly	4/319	25/18722	0.000788556215479643	0.00735091746448256	CHMP1B/CHMP2B/CHMP5/HNRNPU	4
GO:0071675	regulation of mononuclear cell migration	8/319	115/18722	0.000794219186018506	0.00738695718036669	CCL3/DUSP1/CCL4/TNF/CCL20/C5AR1/HMGB1/THBS1	8
GO:0051781	positive regulation of cell division	7/319	89/18722	0.000814881467767898	0.007562026442424	IL1B/VEGFA/OSM/PPBP/EREG/IL1A/YBX1	7
GO:0002720	positive regulation of cytokine production involved in immune response	6/319	65/18722	0.000828731982969399	0.00763882776230314	IL1B/NLRP3/FFAR2/CD81/NR4A3/HLA-A	6
GO:0038034	signal transduction in absence of ligand	6/319	65/18722	0.000828731982969399	0.00763882776230314	BCL2A1/IL1B/MCL1/TNF/IL1A/PF4	6
GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	6/319	65/18722	0.000828731982969399	0.00763882776230314	BCL2A1/IL1B/MCL1/TNF/IL1A/PF4	6
GO:0051403	stress-activated MAPK cascade	12/319	239/18722	0.000854755391837106	0.00786107251866296	GADD45B/DUSP1/TRIB1/IL1B/VEGFA/TNF/ZFP36/DNAJA1/RIPK2/PTGER4/PAGE4/HMGB1	12
GO:0050999	regulation of nitric-oxide synthase activity	5/319	44/18722	0.000876657913749814	0.00802659394972269	IL1B/HIF1A/TNF/IL1A/APOE	5
GO:0060711	labyrinthine layer development	5/319	44/18722	0.000876657913749814	0.00802659394972269	SOCS3/JUNB/DNAJB6/GRB2/HES1	5
GO:0050851	antigen receptor-mediated signaling pathway	12/319	240/18722	0.000886327341434726	0.0080970926680848	NFKBIZ/PDE4B/PRNP/RIPK2/CD81/HLA-DPB1/MNDA/GBP1/HLA-A/DGKZ/HLA-DRB1/NCKAP1L	12
GO:1901361	organic cyclic compound catabolic process	19/319	495/18722	0.000891198073770808	0.00812353720902836	YWHAH/HNRNPM/PDE4B/HNRNPA0/ZFP36/ETF1/LSM6/DDX5/NPM1/HMOX1/YBX3/HNRNPU/SERBP1/TOB1/SSB/SPP1/YBX1/APOE/TYMP	19
GO:0032535	regulation of cellular component size	16/319	382/18722	0.000911376938288284	0.00828909423297154	PPP1R15A/TMSB4X/FN1/ICAM1/VEGFA/GRB2/MYADM/BRK1/NPM1/SEMA4D/HSP90AB1/PLEK/SPP1/APOE/COTL1/NCKAP1L	16
GO:0019883	antigen processing and presentation of endogenous antigen	4/319	26/18722	0.000919526397191946	0.00830807256891448	HLA-C/HLA-A/HLA-DRA/HLA-DRB1	4
GO:0033598	mammary gland epithelial cell proliferation	4/319	26/18722	0.000919526397191946	0.00830807256891448	AREG/ID2/CEBPB/STAT6	4
GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	4/319	26/18722	0.000919526397191946	0.00830807256891448	NFKBIA/TNFAIP3/BIRC3/RIPK2	4
GO:0071453	cellular response to oxygen levels	10/319	177/18722	0.000939447191265796	0.00845707570767302	HIF1A/ICAM1/VEGFA/BNIP3L/PGK1/PMAIP1/PTGS2/HMOX1/EGR1/RGCC	10
GO:0006413	translational initiation	8/319	118/18722	0.000940132230213226	0.00845707570767302	PPP1R15A/PPP1R15B/TNF/EIF1B/NPM1/EIF1/EIF1AX/RPS3A	8
GO:0002790	peptide secretion	12/319	242/18722	0.000952394934961478	0.00852124556168382	IL1B/PIM3/HIF1A/TNF/IRS2/MIDN/FFAR2/SERP1/IL1RN/S100A8/HLA-DRB1/PPP3CA	12
GO:0002424	T cell mediated immune response to tumor cell	3/319	12/18722	0.000961775222724712	0.00852124556168382	HLA-A/HMGB1/HLA-DRB1	3
GO:0002863	positive regulation of inflammatory response to antigenic stimulus	3/319	12/18722	0.000961775222724712	0.00852124556168382	TNF/CD81/C3	3
GO:0033079	immature T cell proliferation	3/319	12/18722	0.000961775222724712	0.00852124556168382	IL1B/RIPK2/IL1A	3
GO:0043380	regulation of memory T cell differentiation	3/319	12/18722	0.000961775222724712	0.00852124556168382	BCL6/HLA-DRA/HLA-DRB1	3
GO:0044650	adhesion of symbiont to host cell	3/319	12/18722	0.000961775222724712	0.00852124556168382	ICAM1/HSP90AB1/CD81	3
GO:0070586	cell-cell adhesion involved in gastrulation	3/319	12/18722	0.000961775222724712	0.00852124556168382	KLF4/MYADM/IL1RN	3
GO:2000273	positive regulation of signaling receptor activity	5/319	45/18722	0.000972658682488872	0.00858589425739867	HIF1A/HBEGF/AREG/IFNGR2/EREG	5
GO:0035914	skeletal muscle cell differentiation	6/319	67/18722	0.000973249020663532	0.00858589425739867	FOS/ATF3/NR4A1/DDX5/EGR1/MAFF	6
GO:2001056	positive regulation of cysteine-type endopeptidase activity	9/319	148/18722	0.00100038789735908	0.00880641251829377	CYCS/ANP32B/TNF/NLRP3/PMAIP1/SNCA/RIPK2/S100A8/HMGB1	9
GO:0006401	RNA catabolic process	13/319	278/18722	0.00101599736480757	0.00892471189470924	HNRNPM/HNRNPA0/ZFP36/ETF1/LSM6/DDX5/NPM1/YBX3/HNRNPU/SERBP1/TOB1/SSB/YBX1	13
GO:0010950	positive regulation of endopeptidase activity	10/319	179/18722	0.00102340717388266	0.00897063303162389	CYCS/ANP32B/TNF/NLRP3/AKIRIN2/PMAIP1/SNCA/RIPK2/S100A8/HMGB1	10
GO:0042742	defense response to bacterium	15/319	350/18722	0.00104048885995018	0.00910095681543654	RPL39/TNF/TREM1/HMGB2/RIPK2/PPBP/CEBPB/CCL20/PLAC8/GBP4/C5AR1/ISG15/DEFB1/S100A8/HLA-A	15
GO:0023061	signal release	18/319	463/18722	0.00104794211341177	0.00913757344368945	IL1B/NR4A1/PIM3/HIF1A/TNF/STX11/OSM/IRS2/HCAR2/MIDN/SNCA/FFAR2/SERP1/IL1RN/SPP1/RETN/HLA-DRB1/PPP3CA	18
GO:0045834	positive regulation of lipid metabolic process	9/319	149/18722	0.00104912057052333	0.00913757344368945	IL1B/TNF/IRS2/PTGS2/CD81/APOE/NR4A3/DGKZ/APOC1	9
GO:0046686	response to cadmium ion	6/319	68/18722	0.0010523986452776	0.00914674594235986	FOS/JUN/SOD2/PRNP/HMOX1/MT2A	6
GO:0032755	positive regulation of interleukin-6 production	7/319	93/18722	0.00105757746406758	0.00917236488350593	IL1B/TNF/AKIRIN2/RIPK2/EREG/IL1A/HMGB1	7
GO:0032703	negative regulation of interleukin-2 production	4/319	27/18722	0.00106508516740413	0.00919866622520664	TNFAIP3/ZFP36/PRNP/GBP1	4
GO:1903203	regulation of oxidative stress-induced neuron death	4/319	27/18722	0.00106508516740413	0.00919866622520664	HIF1A/MCL1/CTNNB1/NR4A3	4
GO:0043409	negative regulation of MAPK cascade	10/319	180/18722	0.00106763538988575	0.00920136077111176	ATF3/KLF4/DUSP2/DUSP1/IL1B/DNAJA1/APOE/TIMP3/GBP1/FBLN1	10
GO:0061028	establishment of endothelial barrier	5/319	46/18722	0.00107625394212867	0.00925623421776349	IL1B/ICAM1/VEGFA/TNF/MYADM	5
GO:0043254	regulation of protein-containing complex assembly	17/319	427/18722	0.00111023951959706	0.00952859011495517	TMSB4X/ICAM1/VEGFA/TNF/MAPRE1/GRB2/MYADM/BRK1/VDAC2/SNCA/PTGER4/PLEK/ISG15/APOE/COTL1/HMGB1/NCKAP1L	17
GO:1990830	cellular response to leukemia inhibitory factor	7/319	94/18722	0.00112631339256259	0.00964640491005172	KLF4/SOCS3/NCL/ICAM1/SRSF3/SRSF7/HNRNPU	7
GO:0031098	stress-activated protein kinase signaling cascade	12/319	247/18722	0.00113571220431623	0.00970667956745117	GADD45B/DUSP1/TRIB1/IL1B/VEGFA/TNF/ZFP36/DNAJA1/RIPK2/PTGER4/PAGE4/HMGB1	12
GO:0019730	antimicrobial humoral response	8/319	122/18722	0.00116728617691913	0.00995583708156546	CXCL8/RPL39/CXCL2/PPBP/HMGN2/PF4/DEFB1/HLA-A	8
GO:0001774	microglial cell activation	5/319	47/18722	0.0011878077866927	0.0100474852080117	CCL3/TNF/SNCA/IFNGR2/C5AR1	5
GO:0019884	antigen processing and presentation of exogenous antigen	5/319	47/18722	0.0011878077866927	0.0100474852080117	HLA-DPB1/HLA-DQA1/HLA-A/HLA-DRA/HLA-DRB1	5
GO:0045601	regulation of endothelial cell differentiation	5/319	47/18722	0.0011878077866927	0.0100474852080117	IL1B/VEGFA/TNF/CTNNB1/BTG1	5
GO:0045646	regulation of erythrocyte differentiation	5/319	47/18722	0.0011878077866927	0.0100474852080117	HIF1A/ZFP36/HMGB2/ISG15/NCKAP1L	5
GO:1990823	response to leukemia inhibitory factor	7/319	95/18722	0.00119850611016854	0.0101171634885069	KLF4/SOCS3/NCL/ICAM1/SRSF3/SRSF7/HNRNPU	7
GO:0051092	positive regulation of NF-kappaB transcription factor activity	9/319	152/18722	0.00120697029743241	0.0101508396104284	IL1B/ICAM1/TNF/NLRP3/PRDX3/NPM1/RIPK2/TRIM22/S100A8	9
GO:1904951	positive regulation of establishment of protein localization	14/319	319/18722	0.00121175746795598	0.0101508396104284	IL1B/HIF1A/ANP32B/TNF/IRS2/PRNP/HCAR2/PTGS2/OAZ1/HSP90AB1/CD81/SERP1/IL1A/HLA-DRB1	14
GO:0002381	immunoglobulin production involved in immunoglobulin-mediated immune response	6/319	70/18722	0.0012254371008386	0.0101508396104284	BCL6/HLA-DPB1/HLA-DQA1/HLA-DRA/STAT6/HLA-DRB1	6
GO:0002548	monocyte chemotaxis	6/319	70/18722	0.0012254371008386	0.0101508396104284	CCL3/DUSP1/CCL4/CCL3L3/CCL20/HMGB1	6
GO:0031342	negative regulation of cell killing	4/319	28/18722	0.00122607962961661	0.0101508396104284	HSP90AB1/SERPINB9/HLA-A/NCKAP1L	4
GO:0071280	cellular response to copper ion	4/319	28/18722	0.00122607962961661	0.0101508396104284	PRNP/SNCA/MT2A/AOC1	4
GO:0006995	cellular response to nitrogen starvation	3/319	13/18722	0.00123459494167215	0.0101508396104284	GABARAPL1/MAP1LC3B/GABARAP	3
GO:0042541	hemoglobin biosynthetic process	3/319	13/18722	0.00123459494167215	0.0101508396104284	KLF4/HIF1A/SLC25A37	3
GO:0043379	memory T cell differentiation	3/319	13/18722	0.00123459494167215	0.0101508396104284	BCL6/HLA-DRA/HLA-DRB1	3
GO:0043562	cellular response to nitrogen levels	3/319	13/18722	0.00123459494167215	0.0101508396104284	GABARAPL1/MAP1LC3B/GABARAP	3
GO:0045741	positive regulation of epidermal growth factor-activated receptor activity	3/319	13/18722	0.00123459494167215	0.0101508396104284	HBEGF/AREG/EREG	3
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	3/319	13/18722	0.00123459494167215	0.0101508396104284	HIF1A/VEGFA/EGR1	3
GO:1902947	regulation of tau-protein kinase activity	3/319	13/18722	0.00123459494167215	0.0101508396104284	HSP90AB1/EGR1/C5AR1	3
GO:1904035	regulation of epithelial cell apoptotic process	7/319	96/18722	0.00127427501285512	0.0104561768020906	TNFAIP3/ICAM1/TNF/ZFP36/HMOX1/RGCC/THBS1	7
GO:0030856	regulation of epithelial cell differentiation	9/319	154/18722	0.00132246974443689	0.010809725853984	IL1B/VEGFA/TNF/ZFP36/CTNNB1/BTG1/CEBPB/MAFF/HES1	9
GO:0008380	RNA splicing	17/319	434/18722	0.00132262031246751	0.010809725853984	SRSF5/NCL/HNRNPA1/SRSF3/HNRNPF/HNRNPM/RNU11/SYF2/LSM6/SRSF7/YTHDC1/DDX5/NPM1/FRG1/BCAS2/HNRNPU/YBX1	17
GO:0009306	protein secretion	15/319	359/18722	0.00133876932370444	0.0109200013685495	IL1B/PIM3/HIF1A/TNF/IRS2/HCAR2/MIDN/ERP29/SERP1/PLEK/IL1A/IL1RN/APOE/HLA-DRB1/PPP3CA	15
GO:0120162	positive regulation of cold-induced thermogenesis	7/319	97/18722	0.00135374137507578	0.011020258995914	G0S2/CXCR4/KDM6B/VEGFA/CEBPB/PLAC8/STAT6	7
GO:0035592	establishment of protein localization to extracellular region	15/319	360/18722	0.00137595465313782	0.0111789517372521	IL1B/PIM3/HIF1A/TNF/IRS2/HCAR2/MIDN/ERP29/SERP1/PLEK/IL1A/IL1RN/APOE/HLA-DRB1/PPP3CA	15
GO:0097305	response to alcohol	12/319	253/18722	0.00139344371456047	0.0112987122496215	FOS/FOSB/KLF4/CCL3/ICAM1/SOD2/CDKN1A/NLRP3/CTNNB1/KLF2/PTGER4/S100A8	12
GO:0043903	regulation of biological process involved in symbiotic interaction	6/319	72/18722	0.00141943896624179	0.011464270314774	CXCL8/CHMP2B/SNX3/TRIM22/FCN1/HLA-DRB1	6
GO:0050709	negative regulation of protein secretion	6/319	72/18722	0.00141943896624179	0.011464270314774	IL1B/PIM3/MIDN/ERP29/APOE/PPP3CA	6
GO:0009409	response to cold	5/319	49/18722	0.00143626863310126	0.0114745896982422	NFKBIA/FOS/METRNL/SOD2/PLAC8	5
GO:0014075	response to amine	5/319	49/18722	0.00143626863310126	0.0114745896982422	NR4A2/NR4A1/ICAM1/RGS10/PPP3CA	5
GO:0030225	macrophage differentiation	5/319	49/18722	0.00143626863310126	0.0114745896982422	TRIB1/VEGFA/ID2/PF4/HLA-DRB1	5
GO:0052372	modulation by symbiont of entry into host	5/319	49/18722	0.00143626863310126	0.0114745896982422	CXCL8/SNX3/TRIM22/FCN1/HLA-DRB1	5
GO:0070301	cellular response to hydrogen peroxide	7/319	98/18722	0.00143702831167032	0.0114745896982422	TNFAIP3/KLF4/KDM6B/PPIF/KLF2/NR4A3/STAT6	7
GO:0044706	multi-multicellular organism process	11/319	220/18722	0.00143746380311231	0.0114745896982422	FOS/FOSB/JUNB/IL1B/VEGFA/PRDX3/VMP1/PTGS2/MAFF/SPP1/FBLN1	11
GO:0051235	maintenance of location	14/319	326/18722	0.00148651508299953	0.0118431463298664	NFKBIA/CCL3/IL1B/TMSB4X/PLIN2/TNF/SRGN/SNCA/FFAR2/FTH1/HNRNPU/APOE/S100A8/C3	14
GO:1990845	adaptive thermogenesis	9/319	157/18722	0.00151227055549107	0.0119855967250537	G0S2/CXCR4/KDM6B/VEGFA/TLE3/CEBPB/HNRNPU/PLAC8/STAT6	9
GO:2000377	regulation of reactive oxygen species metabolic process	9/319	157/18722	0.00151227055549107	0.0119855967250537	HIF1A/SOD2/CDKN1A/TNF/GRB2/SNCA/PAGE4/THBS1/DCXR	9
GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	7/319	99/18722	0.0015242607382296	0.0119855967250537	BCL2A1/DDIT4/MCL1/CDKN1A/TNF/SKIL/HMOX1	7
GO:0031341	regulation of cell killing	7/319	99/18722	0.0015242607382296	0.0119855967250537	ICAM1/HSP90AB1/SERPINB9/HLA-A/HLA-DRA/HLA-DRB1/NCKAP1L	7
GO:0042100	B cell proliferation	7/319	99/18722	0.0015242607382296	0.0119855967250537	CDKN1A/GPR183/IRS2/BCL6/CD81/MNDA/NCKAP1L	7
GO:0050848	regulation of calcium-mediated signaling	6/319	73/18722	0.00152480347535955	0.0119855967250537	CCL3/CCL4/TNF/PRNP/PLEK/GBP1	6
GO:0051145	smooth muscle cell differentiation	6/319	73/18722	0.00152480347535955	0.0119855967250537	SOD2/VEGFA/CTNNB1/EREG/HES1/PIAS1	6
GO:0007517	muscle organ development	14/319	327/18722	0.00152971013339483	0.0120012182411949	FOS/ATF3/NR4A1/HBEGF/CTNNB1/DDX5/FRG1/BASP1/YBX3/SERP1/EGR1/MAFF/VAMP5/PPP3CA	14
GO:0031650	regulation of heat generation	3/319	14/18722	0.001551572430279	0.0120576829128109	IL1B/TNF/PTGS2	3
GO:0043558	regulation of translational initiation in response to stress	3/319	14/18722	0.001551572430279	0.0120576829128109	PPP1R15A/PPP1R15B/NPM1	3
GO:0043922	negative regulation by host of viral transcription	3/319	14/18722	0.001551572430279	0.0120576829128109	CCL3/JUN/CCL4	3
GO:0061043	regulation of vascular wound healing	3/319	14/18722	0.001551572430279	0.0120576829128109	TNFAIP3/CXCR4/TNF	3
GO:0090715	immunological memory formation process	3/319	14/18722	0.001551572430279	0.0120576829128109	BCL6/HLA-DRA/HLA-DRB1	3
GO:0019083	viral transcription	5/319	50/18722	0.0015739236483706	0.0122083021102859	CCL3/JUN/CCL4/ZFP36/CHD1	5
GO:0043488	regulation of mRNA stability	9/319	158/18722	0.00158018943070653	0.0122338206207807	HNRNPM/HNRNPA0/ZFP36/NPM1/YBX3/HNRNPU/SERBP1/TOB1/YBX1	9
GO:0032612	interleukin-1 production	8/319	128/18722	0.00158798158370415	0.0122480155546112	TNFAIP3/CCL3/TNF/NLRP3/RIPK2/EGR1/MNDA/HMGB1	8
GO:0032652	regulation of interleukin-1 production	8/319	128/18722	0.00158798158370415	0.0122480155546112	TNFAIP3/CCL3/TNF/NLRP3/RIPK2/EGR1/MNDA/HMGB1	8
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	4/319	30/18722	0.00159775339358399	0.0122773162635959	HLA-DPB1/HLA-DQA1/HLA-DRA/HLA-DRB1	4
GO:0070229	negative regulation of lymphocyte apoptotic process	4/319	30/18722	0.00159775339358399	0.0122773162635959	HIF1A/IRS2/BCL6/TSC22D3	4
GO:1903201	regulation of oxidative stress-induced cell death	6/319	74/18722	0.00163601693394301	0.012547883610895	HIF1A/SOD2/MCL1/CTNNB1/PAGE4/NR4A3	6
GO:0022411	cellular component disassembly	17/319	443/18722	0.00164542030813978	0.0125965044446232	DDIT4/HIF1A/CHMP1B/BNIP3L/TNF/GABARAPL1/CHMP2B/CHMP5/MAP1LC3B/GABARAP/ETF1/UFC1/VMP1/PLEK/SET/RPL23/C3	17
GO:0032984	protein-containing complex disassembly	11/319	224/18722	0.0016586662386052	0.0126743065184126	DDIT4/CHMP1B/TNF/CHMP2B/CHMP5/MAP1LC3B/ETF1/VMP1/PLEK/SET/RPL23	11
GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	8/319	129/18722	0.00166848008155261	0.0127256430709884	CYCS/ANP32B/TNF/NLRP3/PMAIP1/SNCA/S100A8/HMGB1	8
GO:0071692	protein localization to extracellular region	15/319	368/18722	0.00170588404698958	0.0129868320688411	IL1B/PIM3/HIF1A/TNF/IRS2/HCAR2/MIDN/ERP29/SERP1/PLEK/IL1A/IL1RN/APOE/HLA-DRB1/PPP3CA	15
GO:0019216	regulation of lipid metabolic process	14/319	331/18722	0.00171311026956111	0.013017738111212	IL1B/TNF/IRS2/ID2/HCAR2/SNCA/PTGS2/CD81/EGR1/APOE/NR4A3/C3/DGKZ/APOC1	14
GO:0034284	response to monosaccharide	11/319	225/18722	0.00171810666195239	0.0130316171352145	PIM3/HIF1A/ICAM1/SOD2/LDHA/IRS2/PTGS2/EGR1/THBS1/HLA-DRB1/PPP3CA	11
GO:1902369	negative regulation of RNA catabolic process	6/319	75/18722	0.00175328739421032	0.0132739677303842	HNRNPA0/ZFP36/YBX3/HNRNPU/TOB1/YBX1	6
GO:0050890	cognition	13/319	296/18722	0.00178224987644115	0.0134684361067088	FOS/JUN/HIF1A/SGK1/TNF/CHMP2B/PRNP/PTGS2/CEBPB/C5AR1/APOE/HLA-DRA/PIAS1	13
GO:0007565	female pregnancy	10/319	193/18722	0.00179924918108692	0.0135357010877646	FOS/FOSB/JUNB/IL1B/VEGFA/PRDX3/VMP1/PTGS2/SPP1/FBLN1	10
GO:0002828	regulation of type 2 immune response	4/319	31/18722	0.00181011149039205	0.0135357010877646	NLRP3/BCL6/CD81/STAT6	4
GO:0036475	neuron death in response to oxidative stress	4/319	31/18722	0.00181011149039205	0.0135357010877646	HIF1A/MCL1/CTNNB1/NR4A3	4
GO:0060055	angiogenesis involved in wound healing	4/319	31/18722	0.00181011149039205	0.0135357010877646	TNFAIP3/CXCR4/VEGFA/TNF	4
GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	4/319	31/18722	0.00181011149039205	0.0135357010877646	TNFAIP3/ICAM1/HMGB2/HMOX1	4
GO:0032677	regulation of interleukin-8 production	7/319	102/18722	0.00181090625109961	0.0135357010877646	KLF4/IL1B/TMSB4X/TNF/FFAR2/FCN1/HMGB1	7
GO:0045089	positive regulation of innate immune response	8/319	131/18722	0.00183915052167458	0.0136970068742829	AKIRIN2/HMGB2/FFAR2/NMI/EREG/FCN1/MNDA/HMGB1	8
GO:1904950	negative regulation of establishment of protein localization	8/319	131/18722	0.00183915052167458	0.0136970068742829	IL1B/PIM3/DNAJA1/MIDN/SNX3/ERP29/APOE/PPP3CA	8
GO:2000379	positive regulation of reactive oxygen species metabolic process	6/319	76/18722	0.00187682526425495	0.0139523122266765	SOD2/CDKN1A/GRB2/SNCA/THBS1/DCXR	6
GO:0002468	dendritic cell antigen processing and presentation	3/319	15/18722	0.00191513302639832	0.0141353770866235	HLA-DRA/THBS1/HLA-DRB1	3
GO:0044406	adhesion of symbiont to host	3/319	15/18722	0.00191513302639832	0.0141353770866235	ICAM1/HSP90AB1/CD81	3
GO:0090594	inflammatory response to wounding	3/319	15/18722	0.00191513302639832	0.0141353770866235	HIF1A/HMOX1/IL1A	3
GO:0032637	interleukin-8 production	7/319	103/18722	0.00191520433890763	0.0141353770866235	KLF4/IL1B/TMSB4X/TNF/FFAR2/FCN1/HMGB1	7
GO:0007569	cell aging	8/319	132/18722	0.00192950028536621	0.0141899385923801	ICAM1/CDKN1A/BCL6/ID2/LIMS1/NPM1/ZMIZ1/YBX1	8
GO:0045667	regulation of osteoblast differentiation	8/319	132/18722	0.00192950028536621	0.0141899385923801	JUND/TNF/AREG/CTNNB1/DDX5/SEMA4D/CEBPB/TOB1	8
GO:0030073	insulin secretion	10/319	195/18722	0.00194118881242465	0.0142504057283531	IL1B/PIM3/HIF1A/TNF/IRS2/MIDN/SERP1/IL1RN/HLA-DRB1/PPP3CA	10
GO:0050657	nucleic acid transport	9/319	163/18722	0.00195745675780253	0.0143186916927513	HNRNPA1/SRSF3/ZFP36/SRSF7/YTHDC1/NPM1/MX2/SSB/YBX1	9
GO:0050658	RNA transport	9/319	163/18722	0.00195745675780253	0.0143186916927513	HNRNPA1/SRSF3/ZFP36/SRSF7/YTHDC1/NPM1/MX2/SSB/YBX1	9
GO:0071695	anatomical structure maturation	11/319	229/18722	0.00197353210991341	0.0144106403265613	NR4A2/HIF1A/VEGFA/CDKN1A/CTNNB1/SEMA4D/KLF2/EREG/HES1/DEFB1/C3	11
GO:0015833	peptide transport	12/319	264/18722	0.0019913006939159	0.014514604880653	IL1B/PIM3/HIF1A/TNF/IRS2/MIDN/FFAR2/SERP1/IL1RN/S100A8/HLA-DRB1/PPP3CA	12
GO:0090276	regulation of peptide hormone secretion	10/319	196/18722	0.00201547410326106	0.0146648036079756	IL1B/PIM3/HIF1A/TNF/IRS2/MIDN/FFAR2/SERP1/HLA-DRB1/PPP3CA	10
GO:0016925	protein sumoylation	5/319	53/18722	0.00204513998002209	0.0148122148661366	CTNNB1/ZMIZ1/EGR1/SUMO2/PIAS1	5
GO:1903202	negative regulation of oxidative stress-induced cell death	5/319	53/18722	0.00204513998002209	0.0148122148661366	HIF1A/SOD2/CTNNB1/PAGE4/NR4A3	5
GO:0018108	peptidyl-tyrosine phosphorylation	15/319	375/18722	0.00204654294428742	0.0148122148661366	SOCS3/ICAM1/VEGFA/TNF/HBEGF/OSM/AREG/SAMSN1/PRNP/RIPK2/SEMA4D/CD81/EREG/HES1/CSH1	15
GO:0045732	positive regulation of protein catabolic process	11/319	231/18722	0.00211237607292146	0.0152618243159581	TNFAIP3/TRIB1/IL1B/TNF/GABARAP/OAZ1/CD81/SUMO2/RNF19B/APOE/PIAS1	11
GO:0050796	regulation of insulin secretion	9/319	165/18722	0.00212714113837262	0.0153415389821927	IL1B/PIM3/HIF1A/TNF/IRS2/MIDN/SERP1/HLA-DRB1/PPP3CA	9
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	6/319	78/18722	0.00214355589622572	0.0153789847982267	CYCS/ANP32B/TNF/PMAIP1/SNCA/S100A8	6
GO:0043537	negative regulation of blood vessel endothelial cell migration	6/319	78/18722	0.00214355589622572	0.0153789847982267	KLF4/TNF/RGCC/APOE/HMGB1/THBS1	6
GO:0070373	negative regulation of ERK1 and ERK2 cascade	6/319	78/18722	0.00214355589622572	0.0153789847982267	ATF3/KLF4/DUSP1/TIMP3/GBP1/FBLN1	6
GO:0010594	regulation of endothelial cell migration	11/319	232/18722	0.00218471726804924	0.0156469907473004	KLF4/TMSB4X/HIF1A/VEGFA/TNF/PTGS2/HMOX1/RGCC/APOE/HMGB1/THBS1	11
GO:0018212	peptidyl-tyrosine modification	15/319	378/18722	0.00220896434369789	0.0157904487046718	SOCS3/ICAM1/VEGFA/TNF/HBEGF/OSM/AREG/SAMSN1/PRNP/RIPK2/SEMA4D/CD81/EREG/HES1/CSH1	15
GO:0051236	establishment of RNA localization	9/319	166/18722	0.00221627071335335	0.0157904487046718	HNRNPA1/SRSF3/ZFP36/SRSF7/YTHDC1/NPM1/MX2/SSB/YBX1	9
GO:0061013	regulation of mRNA catabolic process	9/319	166/18722	0.00221627071335335	0.0157904487046718	HNRNPM/HNRNPA0/ZFP36/NPM1/YBX3/HNRNPU/SERBP1/TOB1/YBX1	9
GO:0009314	response to radiation	17/319	456/18722	0.00222727205822091	0.0158413761787996	FOS/JUND/JUN/DUSP1/BHLHE40/HIF1A/ICAM1/SOD2/CDKN1A/GRB2/ID2/NPM1/PTGS2/HMGN1/EGR1/ADIRF/PIAS1	17
GO:0007346	regulation of mitotic cell cycle	17/319	457/18722	0.00227839339040465	0.0161068380504286	KLF4/DUSP1/IL1B/PIM3/CDKN1A/TNF/CTNNB1/BCL6/ID2/SYF2/BTG1/TMEM14B/HNRNPU/EREG/RGCC/IL1A/HES1	17
GO:0006446	regulation of translational initiation	6/319	79/18722	0.00228718012402873	0.0161068380504286	PPP1R15A/PPP1R15B/TNF/EIF1B/NPM1/EIF1	6
GO:0032633	interleukin-4 production	4/319	33/18722	0.00229202146910746	0.0161068380504286	CD83/NLRP3/CEBPB/HLA-DRB1	4
GO:0032673	regulation of interleukin-4 production	4/319	33/18722	0.00229202146910746	0.0161068380504286	CD83/NLRP3/CEBPB/HLA-DRB1	4
GO:0045648	positive regulation of erythrocyte differentiation	4/319	33/18722	0.00229202146910746	0.0161068380504286	HIF1A/HMGB2/ISG15/NCKAP1L	4
GO:0071353	cellular response to interleukin-4	4/319	33/18722	0.00229202146910746	0.0161068380504286	NFIL3/HSP90AB1/RPL3/STAT6	4
GO:1903715	regulation of aerobic respiration	4/319	33/18722	0.00229202146910746	0.0161068380504286	HIF1A/PPIF/COX7A2L/SNCA	4
GO:1903034	regulation of response to wounding	9/319	167/18722	0.00230834876970769	0.016190383407764	TNFAIP3/KLF4/CXCR4/TNF/HBEGF/SPP1/APOE/HMGB1/THBS1	9
GO:0045727	positive regulation of translation	8/319	136/18722	0.00232645590730583	0.016190383407764	PPP1R15A/TNF/NPM1/YBX3/SERP1/TOB1/RPL5/THBS1	8
GO:0009299	mRNA transcription	3/319	16/18722	0.00232753991583277	0.016190383407764	DDX5/EREG/C5AR1	3
GO:0045651	positive regulation of macrophage differentiation	3/319	16/18722	0.00232753991583277	0.016190383407764	TRIB1/ID2/PF4	3
GO:0051044	positive regulation of membrane protein ectodomain proteolysis	3/319	16/18722	0.00232753991583277	0.016190383407764	IL1B/TNF/APOE	3
GO:0070431	nucleotide-binding oligomerization domain containing 2 signaling pathway	3/319	16/18722	0.00232753991583277	0.016190383407764	NFKBIA/TNFAIP3/RIPK2	3
GO:0008637	apoptotic mitochondrial changes	7/319	107/18722	0.00237970803508535	0.0165253036017498	JUN/PLAUR/SOD2/BNIP3L/PPIF/VDAC2/PMAIP1	7
GO:0002833	positive regulation of response to biotic stimulus	9/319	168/18722	0.00240344392657666	0.0166619864791849	AKIRIN2/HMGB2/FFAR2/NMI/EREG/FCN1/MNDA/HMGB1/HLA-DRB1	9
GO:0038066	p38MAPK cascade	5/319	55/18722	0.00241166858599329	0.0166628059781822	GADD45B/DUSP1/IL1B/VEGFA/ZFP36	5
GO:0043331	response to dsRNA	5/319	55/18722	0.00241166858599329	0.0166628059781822	NFKBIA/PMAIP1/NPM1/RIPK2/IFIT1	5
GO:0006403	RNA localization	10/319	201/18722	0.00242206626297974	0.0167065677971639	HNRNPA1/SRSF3/ZFP36/SRSF7/YTHDC1/NPM1/HNRNPU/MX2/SSB/YBX1	10
GO:0050684	regulation of mRNA processing	8/319	137/18722	0.00243505028710249	0.0167597800458186	NCL/HNRNPA1/SRSF3/SRSF7/YTHDC1/DDX5/NPM1/HNRNPU	8
GO:0009791	post-embryonic development	6/319	80/18722	0.00243793443624411	0.0167597800458186	KLF4/NR4A2/VEGFA/CSRNP1/HMGN1/SERP1	6
GO:0030072	peptide hormone secretion	11/319	236/18722	0.00249448139147974	0.0171198881475345	IL1B/PIM3/HIF1A/TNF/IRS2/MIDN/FFAR2/SERP1/IL1RN/HLA-DRB1/PPP3CA	11
GO:0031214	biomineral tissue development	9/319	169/18722	0.00250162555016258	0.0171403043945306	CCL3/HIF1A/KLF10/SBDS/SRGN/PTGS2/CEBPB/SPP1/ISG15	9
GO:0033138	positive regulation of peptidyl-serine phosphorylation	7/319	108/18722	0.00250834673611256	0.017157759454507	VEGFA/TNF/OSM/SNCA/RIPK2/PTGS2/HSP90AB1	7
GO:0051962	positive regulation of nervous system development	12/319	272/18722	0.0025466745579601	0.0173909951956378	IL1B/FN1/CXCR4/HIF1A/VEGFA/TNF/CTNNB1/ID2/SKIL/SEMA4D/HES1/NAP1L1	12
GO:0002495	antigen processing and presentation of peptide antigen via MHC class II	4/319	34/18722	0.00256320998327949	0.0174076850590904	HLA-DPB1/HLA-DQA1/HLA-DRA/HLA-DRB1	4
GO:0010922	positive regulation of phosphatase activity	4/319	34/18722	0.00256320998327949	0.0174076850590904	PPP1R15A/PPP1R15B/HSP90AB1/PLEK	4
GO:0032770	positive regulation of monooxygenase activity	4/319	34/18722	0.00256320998327949	0.0174076850590904	IL1B/HIF1A/TNF/APOE	4
GO:0014706	striated muscle tissue development	15/319	384/18722	0.00256605622617581	0.0174076850590904	FOS/ATF3/NR4A1/KDM6B/VEGFA/PIM1/CTNNB1/ID2/DDX5/YBX3/HNRNPU/EGR1/MAFF/VAMP5/PPP3CA	15
GO:0051817	modulation of process of other organism involved in symbiotic interaction	6/319	81/18722	0.00259603911963833	0.0175730750729426	CCL3/JUN/CCL4/SERPINB9/CHD1/APOE	6
GO:0043487	regulation of RNA stability	9/319	170/18722	0.00260296374216921	0.0175730750729426	HNRNPM/HNRNPA0/ZFP36/NPM1/YBX3/HNRNPU/SERBP1/TOB1/YBX1	9
GO:0032608	interferon-beta production	5/319	56/18722	0.00261180950366527	0.0175730750729426	HMGB2/RIPK2/NMI/ISG15/HMGB1	5
GO:0032648	regulation of interferon-beta production	5/319	56/18722	0.00261180950366527	0.0175730750729426	HMGB2/RIPK2/NMI/ISG15/HMGB1	5
GO:0048255	mRNA stabilization	5/319	56/18722	0.00261180950366527	0.0175730750729426	HNRNPA0/ZFP36/YBX3/HNRNPU/YBX1	5
GO:0110148	biomineralization	9/319	171/18722	0.00270752932784348	0.0181873416123604	CCL3/HIF1A/KLF10/SBDS/SRGN/PTGS2/CEBPB/SPP1/ISG15	9
GO:0001910	regulation of leukocyte mediated cytotoxicity	6/319	82/18722	0.00276171604685396	0.0184163564535454	ICAM1/SERPINB9/HLA-A/HLA-DRA/HLA-DRB1/NCKAP1L	6
GO:1904659	glucose transmembrane transport	7/319	110/18722	0.00278161773378906	0.0184163564535454	IL1B/TNF/IRS2/PPBP/SLC2A3/NR4A3/C3	7
GO:1905954	positive regulation of lipid localization	7/319	110/18722	0.00278161773378906	0.0184163564535454	NFKBIA/IL1B/PLIN2/SPP1/APOE/C3/RETN	7
GO:0050768	negative regulation of neurogenesis	8/319	140/18722	0.00278481559384957	0.0184163564535454	IL1B/YWHAH/TNF/CTNNB1/SEMA4D/HES1/SPP1/PPP3CA	8
GO:0001780	neutrophil homeostasis	3/319	17/18722	0.00279090004148839	0.0184163564535454	PDE4B/HCAR2/HMGB1	3
GO:0020027	hemoglobin metabolic process	3/319	17/18722	0.00279090004148839	0.0184163564535454	KLF4/HIF1A/SLC25A37	3
GO:0045591	positive regulation of regulatory T cell differentiation	3/319	17/18722	0.00279090004148839	0.0184163564535454	BCL6/HLA-DRA/HLA-DRB1	3
GO:0060644	mammary gland epithelial cell differentiation	3/319	17/18722	0.00279090004148839	0.0184163564535454	HIF1A/ID2/CEBPB	3
GO:0061952	midbody abscission	3/319	17/18722	0.00279090004148839	0.0184163564535454	CHMP1B/CHMP2B/CHMP5	3
GO:1901550	regulation of endothelial cell development	3/319	17/18722	0.00279090004148839	0.0184163564535454	IL1B/VEGFA/TNF	3
GO:1903140	regulation of establishment of endothelial barrier	3/319	17/18722	0.00279090004148839	0.0184163564535454	IL1B/VEGFA/TNF	3
GO:0001893	maternal placenta development	4/319	35/18722	0.00285562910234505	0.0186934573881218	JUNB/PRDX3/PTGS2/SPP1	4
GO:0019068	virion assembly	4/319	35/18722	0.00285562910234505	0.0186934573881218	CHMP1B/CHMP2B/CHMP5/APOE	4
GO:0048821	erythrocyte development	4/319	35/18722	0.00285562910234505	0.0186934573881218	BCL6/KLF2/RPS6/NCKAP1L	4
GO:0060236	regulation of mitotic spindle organization	4/319	35/18722	0.00285562910234505	0.0186934573881218	CHMP1B/CHMP2B/CHMP5/HNRNPU	4
GO:0097421	liver regeneration	4/319	35/18722	0.00285562910234505	0.0186934573881218	SRSF5/HMOX1/CEBPB/RPS15	4
GO:0001938	positive regulation of endothelial cell proliferation	7/319	111/18722	0.00292653468203045	0.0191271606960686	NR4A1/HIF1A/VEGFA/HMGB2/HMOX1/LRG1/HMGB1	7
GO:0046034	ATP metabolic process	12/319	277/18722	0.00295369734093278	0.0192740472517058	TMSB4X/DDIT4/HIF1A/CYCS/PPIF/COX7A2L/LDHA/PGK1/SNCA/NDUFS5/ATP6V1B2/NDUFA6	12
GO:0043666	regulation of phosphoprotein phosphatase activity	5/319	58/18722	0.0030477899739472	0.0198565207335926	PPP1R15A/PPP1R15B/TNF/HSP90AB1/NCKAP1L	5
GO:0043542	endothelial cell migration	12/319	279/18722	0.0031306138163252	0.0203638503147356	KLF4/TMSB4X/NR4A1/HIF1A/VEGFA/TNF/PTGS2/HMOX1/RGCC/APOE/HMGB1/THBS1	12
GO:0052126	movement in host environment	9/319	175/18722	0.00315950673370986	0.0204586541502279	CXCL8/CXCR4/ICAM1/CHMP2B/SNX3/CD81/TRIM22/FCN1/HLA-DRB1	9
GO:0010923	negative regulation of phosphatase activity	4/319	36/18722	0.00317007119768796	0.0204586541502279	PPP1R15A/TNF/SEMA4D/NCKAP1L	4
GO:0042092	type 2 immune response	4/319	36/18722	0.00317007119768796	0.0204586541502279	NLRP3/BCL6/CD81/STAT6	4
GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	4/319	36/18722	0.00317007119768796	0.0204586541502279	PLAUR/HBEGF/AREG/EREG	4
GO:0070670	response to interleukin-4	4/319	36/18722	0.00317007119768796	0.0204586541502279	NFIL3/HSP90AB1/RPL3/STAT6	4
GO:0050728	negative regulation of inflammatory response	9/319	176/18722	0.00328129610434727	0.0209073896104399	TNFAIP3/KLF4/SOCS3/METRNL/NLRP3/ZFP36/PTGER4/APOE/HLA-DRB1	9
GO:0001836	release of cytochrome c from mitochondria	5/319	59/18722	0.00328440864603517	0.0209073896104399	JUN/PLAUR/SOD2/PPIF/PMAIP1	5
GO:0051353	positive regulation of oxidoreductase activity	5/319	59/18722	0.00328440864603517	0.0209073896104399	IL1B/HIF1A/TNF/SNCA/APOE	5
GO:2000351	regulation of endothelial cell apoptotic process	5/319	59/18722	0.00328440864603517	0.0209073896104399	TNFAIP3/ICAM1/TNF/RGCC/THBS1	5
GO:0006595	polyamine metabolic process	3/319	18/18722	0.00330716984087029	0.0209073896104399	SAT1/OAZ1/AOC1	3
GO:0030730	sequestering of triglyceride	3/319	18/18722	0.00330716984087029	0.0209073896104399	IL1B/PLIN2/TNF	3
GO:0034134	toll-like receptor 2 signaling pathway	3/319	18/18722	0.00330716984087029	0.0209073896104399	TNFAIP3/RIPK2/HMGB1	3
GO:0035743	CD4-positive, alpha-beta T cell cytokine production	3/319	18/18722	0.00330716984087029	0.0209073896104399	IL1B/NLRP3/CD81	3
GO:0097709	connective tissue replacement	3/319	18/18722	0.00330716984087029	0.0209073896104399	HIF1A/IL1A/PPP3CA	3
GO:0150078	positive regulation of neuroinflammatory response	3/319	18/18722	0.00330716984087029	0.0209073896104399	CCL3/IL1B/TNF	3
GO:2000136	regulation of cell proliferation involved in heart morphogenesis	3/319	18/18722	0.00330716984087029	0.0209073896104399	PIM1/CTNNB1/HES1	3
GO:0033135	regulation of peptidyl-serine phosphorylation	8/319	144/18722	0.00331080287920126	0.0209073896104399	DDIT4/VEGFA/TNF/OSM/SNCA/RIPK2/PTGS2/HSP90AB1	8
GO:0106106	cold-induced thermogenesis	8/319	144/18722	0.00331080287920126	0.0209073896104399	G0S2/CXCR4/KDM6B/VEGFA/TLE3/CEBPB/PLAC8/STAT6	8
GO:0120161	regulation of cold-induced thermogenesis	8/319	144/18722	0.00331080287920126	0.0209073896104399	G0S2/CXCR4/KDM6B/VEGFA/TLE3/CEBPB/PLAC8/STAT6	8
GO:0008645	hexose transmembrane transport	7/319	114/18722	0.00339614373453765	0.0214134154795771	IL1B/TNF/IRS2/PPBP/SLC2A3/NR4A3/C3	7
GO:0043405	regulation of MAP kinase activity	9/319	177/18722	0.00340675229611948	0.0214474099377445	DUSP1/TRIB1/IL1B/VEGFA/TNF/DNAJA1/ERP29/APOE/THBS1	9
GO:0051961	negative regulation of nervous system development	8/319	145/18722	0.00345361822165421	0.0217092117877989	IL1B/YWHAH/TNF/CTNNB1/SEMA4D/HES1/SPP1/PPP3CA	8
GO:0002369	T cell cytokine production	4/319	37/18722	0.0035073163340688	0.0218794801962926	IL1B/NLRP3/CD81/HLA-A	4
GO:0002724	regulation of T cell cytokine production	4/319	37/18722	0.0035073163340688	0.0218794801962926	IL1B/NLRP3/CD81/HLA-A	4
GO:0042401	cellular biogenic amine biosynthetic process	4/319	37/18722	0.0035073163340688	0.0218794801962926	NR4A2/SAT1/SNCA/OAZ1	4
GO:0043029	T cell homeostasis	4/319	37/18722	0.0035073163340688	0.0218794801962926	PMAIP1/TSC22D3/RPS6/NCKAP1L	4
GO:0071542	dopaminergic neuron differentiation	4/319	37/18722	0.0035073163340688	0.0218794801962926	NR4A2/HIF1A/VEGFA/CTNNB1	4
GO:0051851	modulation by host of symbiont process	5/319	60/18722	0.00353396537211389	0.0219790191297431	CCL3/JUN/CCL4/CHD1/APOE	5
GO:1903670	regulation of sprouting angiogenesis	5/319	60/18722	0.00353396537211389	0.0219790191297431	KLF4/VEGFA/KLF2/HMGB1/THBS1	5
GO:0006469	negative regulation of protein kinase activity	10/319	212/18722	0.00354928363082755	0.0220409441183264	TNFAIP3/GADD45B/DUSP1/TRIB1/IL1B/CDKN1A/DNAJA1/NPM1/SNCA/APOE	10
GO:1903578	regulation of ATP metabolic process	6/319	87/18722	0.00371154415369596	0.02301381299524	TMSB4X/DDIT4/HIF1A/PPIF/COX7A2L/SNCA	6
GO:0015749	monosaccharide transmembrane transport	7/319	116/18722	0.00373972991658044	0.0231536591672624	IL1B/TNF/IRS2/PPBP/SLC2A3/NR4A3/C3	7
GO:0034113	heterotypic cell-cell adhesion	5/319	61/18722	0.00379684870321983	0.0234367042326377	KLF4/IL1B/TNF/MYADM/IL1RN	5
GO:0050994	regulation of lipid catabolic process	5/319	61/18722	0.00379684870321983	0.0234367042326377	IL1B/TNF/IRS2/HCAR2/APOC1	5
GO:0009309	amine biosynthetic process	4/319	38/18722	0.00386813131108196	0.0236896272153255	NR4A2/SAT1/SNCA/OAZ1	4
GO:0097242	amyloid-beta clearance	4/319	38/18722	0.00386813131108196	0.0236896272153255	TNF/C5AR1/APOE/C3	4
GO:1901186	positive regulation of ERBB signaling pathway	4/319	38/18722	0.00386813131108196	0.0236896272153255	PLAUR/HBEGF/AREG/EREG	4
GO:2000279	negative regulation of DNA biosynthetic process	4/319	38/18722	0.00386813131108196	0.0236896272153255	DUSP1/HNRNPA1/CDKN1A/HNRNPU	4
GO:0002523	leukocyte migration involved in inflammatory response	3/319	19/18722	0.00387816081632549	0.0236896272153255	NLRP3/FFAR2/S100A8	3
GO:0061323	cell proliferation involved in heart morphogenesis	3/319	19/18722	0.00387816081632549	0.0236896272153255	PIM1/CTNNB1/HES1	3
GO:1903204	negative regulation of oxidative stress-induced neuron death	3/319	19/18722	0.00387816081632549	0.0236896272153255	HIF1A/CTNNB1/NR4A3	3
GO:0002702	positive regulation of production of molecular mediator of immune response	7/319	117/18722	0.00392112158855414	0.0239165146150535	IL1B/NLRP3/FFAR2/CD81/NR4A3/HLA-A/STAT6	7
GO:0060537	muscle tissue development	15/319	403/18722	0.00402547116301932	0.0245166102980332	FOS/ATF3/NR4A1/KDM6B/VEGFA/PIM1/CTNNB1/ID2/DDX5/YBX3/HNRNPU/EGR1/MAFF/VAMP5/PPP3CA	15
GO:0016525	negative regulation of angiogenesis	8/319	149/18722	0.00407324126765234	0.0246626467573713	KLF4/TNF/PGK1/CTNNB1/KLF2/RGCC/PF4/THBS1	8
GO:0032368	regulation of lipid transport	8/319	149/18722	0.00407324126765234	0.0246626467573713	NFKBIA/IL1B/IRS2/SPP1/APOE/THBS1/RETN/APOC1	8
GO:0051592	response to calcium ion	8/319	149/18722	0.00407324126765234	0.0246626467573713	FOS/FOSB/JUND/DUSP1/JUNB/PPIF/THBS1/PPP3CA	8
GO:0032757	positive regulation of interleukin-8 production	5/319	62/18722	0.00407344615622844	0.0246626467573713	IL1B/TNF/FFAR2/FCN1/HMGB1	5
GO:0034219	carbohydrate transmembrane transport	7/319	118/18722	0.00410911190844952	0.0248419986112294	IL1B/TNF/IRS2/PPBP/SLC2A3/NR4A3/C3	7
GO:1900407	regulation of cellular response to oxidative stress	6/319	89/18722	0.00415238623594312	0.0250667545021471	HIF1A/SOD2/MCL1/CTNNB1/PAGE4/NR4A3	6
GO:0007596	blood coagulation	10/319	217/18722	0.00418308575712059	0.0252150521224674	FN1/PLAUR/TLN1/ANXA5/PLEK/APOE/PF4/FBLN1/THBS1/DGKZ	10
GO:0046700	heterocycle catabolic process	16/319	445/18722	0.00421506445721905	0.0253706149101428	HNRNPM/PDE4B/HNRNPA0/ZFP36/ETF1/LSM6/DDX5/NPM1/HMOX1/YBX3/HNRNPU/SERBP1/TOB1/SSB/YBX1/TYMP	16
GO:0009743	response to carbohydrate	11/319	253/18722	0.00423107662929418	0.025377631242441	PIM3/HIF1A/ICAM1/SOD2/LDHA/IRS2/PTGS2/EGR1/THBS1/HLA-DRB1/PPP3CA	11
GO:0001914	regulation of T cell mediated cytotoxicity	4/319	39/18722	0.0042532687730581	0.025377631242441	HLA-A/HLA-DRA/HLA-DRB1/NCKAP1L	4
GO:0002347	response to tumor cell	4/319	39/18722	0.0042532687730581	0.025377631242441	KLF4/HLA-A/HMGB1/HLA-DRB1	4
GO:0032728	positive regulation of interferon-beta production	4/319	39/18722	0.0042532687730581	0.025377631242441	HMGB2/RIPK2/ISG15/HMGB1	4
GO:0045923	positive regulation of fatty acid metabolic process	4/319	39/18722	0.0042532687730581	0.025377631242441	IL1B/IRS2/PTGS2/NR4A3	4
GO:0090224	regulation of spindle organization	4/319	39/18722	0.0042532687730581	0.025377631242441	CHMP1B/CHMP2B/CHMP5/HNRNPU	4
GO:0030282	bone mineralization	7/319	119/18722	0.00430385153525793	0.0256422226977469	CCL3/HIF1A/KLF10/SBDS/SRGN/PTGS2/ISG15	7
GO:0002704	negative regulation of leukocyte mediated immunity	5/319	63/18722	0.00436414387411986	0.0259638139891559	BCL6/HMOX1/SERPINB9/HLA-A/NCKAP1L	5
GO:0045638	negative regulation of myeloid cell differentiation	6/319	90/18722	0.00438677486806649	0.026023133452556	NFKBIA/CCL3/TRIB1/ZFP36/CTNNB1/PF4	6
GO:1904705	regulation of vascular associated smooth muscle cell proliferation	6/319	90/18722	0.00438677486806649	0.026023133452556	JUN/SOD2/CDKN1A/TNF/HMOX1/NR4A3	6
GO:0034655	nucleobase-containing compound catabolic process	15/319	407/18722	0.00440603433909393	0.0260690517879608	HNRNPM/PDE4B/HNRNPA0/ZFP36/ETF1/LSM6/DDX5/NPM1/YBX3/HNRNPU/SERBP1/TOB1/SSB/YBX1/TYMP	15
GO:0044409	entry into host	8/319	151/18722	0.00441353929565087	0.0260690517879608	CXCL8/CXCR4/ICAM1/SNX3/CD81/TRIM22/FCN1/HLA-DRB1	8
GO:2000181	negative regulation of blood vessel morphogenesis	8/319	151/18722	0.00441353929565087	0.0260690517879608	KLF4/TNF/PGK1/CTNNB1/KLF2/RGCC/PF4/THBS1	8
GO:0009746	response to hexose	10/319	219/18722	0.00446032487457096	0.0262727592311074	PIM3/HIF1A/ICAM1/LDHA/IRS2/PTGS2/EGR1/THBS1/HLA-DRB1/PPP3CA	10
GO:0051924	regulation of calcium ion transport	11/319	255/18722	0.00448668114615411	0.0262727592311074	CCL3/CCL4/CXCR4/ICAM1/SARAF/PDE4B/CTNNB1/PRNP/VMP1/SNCA/PTGS2	11
GO:1903362	regulation of cellular protein catabolic process	11/319	255/18722	0.00448668114615411	0.0262727592311074	TNFAIP3/TRIB1/GABARAP/HSP90AB1/CD81/SUMO2/RNF19B/RPL23/APOE/RPL5/PIAS1	11
GO:0010632	regulation of epithelial cell migration	12/319	292/18722	0.00450088770277117	0.0262727592311074	KLF4/TMSB4X/HIF1A/VEGFA/TNF/HBEGF/PTGS2/HMOX1/RGCC/APOE/HMGB1/THBS1	12
GO:0071774	response to fibroblast growth factor	7/319	120/18722	0.00450549182600956	0.0262727592311074	CXCL8/NR4A1/IER2/ZFP36/CTNNB1/SNCA/THBS1	7
GO:0043555	regulation of translation in response to stress	3/319	20/18722	0.00450554494233294	0.0262727592311074	PPP1R15A/PPP1R15B/NPM1	3
GO:0045063	T-helper 1 cell differentiation	3/319	20/18722	0.00450554494233294	0.0262727592311074	RIPK2/HMGB1/STAT6	3
GO:0072567	chemokine (C-X-C motif) ligand 2 production	3/319	20/18722	0.00450554494233294	0.0262727592311074	KLF4/TNF/HMGB1	3
GO:2000341	regulation of chemokine (C-X-C motif) ligand 2 production	3/319	20/18722	0.00450554494233294	0.0262727592311074	KLF4/TNF/HMGB1	3
GO:1901343	negative regulation of vasculature development	8/319	152/18722	0.00459168201777412	0.0267371172451408	KLF4/TNF/PGK1/CTNNB1/KLF2/RGCC/PF4/THBS1	8
GO:0002064	epithelial cell development	10/319	220/18722	0.00460427063987852	0.0267721065445192	IL1B/CXCR4/HIF1A/ICAM1/VEGFA/CDKN1A/TNF/FOSL2/MYADM/RILPL2	10
GO:0034976	response to endoplasmic reticulum stress	11/319	256/18722	0.00461900817026933	0.0267721065445192	ATF3/PPP1R15A/CXCL8/JUN/PPP1R15B/PMAIP1/UFC1/ERP29/CEBPB/SERP1/THBS1	11
GO:1990874	vascular associated smooth muscle cell proliferation	6/319	91/18722	0.00463078194107696	0.0267721065445192	JUN/SOD2/CDKN1A/TNF/HMOX1/NR4A3	6
GO:0030866	cortical actin cytoskeleton organization	4/319	40/18722	0.00466346638461457	0.0267721065445192	TNF/TLN1/PLEK/NCKAP1L	4
GO:0070266	necroptotic process	4/319	40/18722	0.00466346638461457	0.0267721065445192	BIRC3/PPIF/TNF/YBX3	4
GO:0071276	cellular response to cadmium ion	4/319	40/18722	0.00466346638461457	0.0267721065445192	FOS/JUN/HMOX1/MT2A	4
GO:0150077	regulation of neuroinflammatory response	4/319	40/18722	0.00466346638461457	0.0267721065445192	CCL3/IL1B/TNF/PTGS2	4
GO:1901223	negative regulation of NIK/NF-kappaB signaling	4/319	40/18722	0.00466346638461457	0.0267721065445192	TMSB4X/NLRP3/LITAF/NMI	4
GO:0001885	endothelial cell development	5/319	64/18722	0.00466932629346152	0.0267721065445192	IL1B/ICAM1/VEGFA/TNF/MYADM	5
GO:0046888	negative regulation of hormone secretion	5/319	64/18722	0.00466932629346152	0.0267721065445192	IL1B/PIM3/OSM/MIDN/PPP3CA	5
GO:0048247	lymphocyte chemotaxis	5/319	64/18722	0.00466932629346152	0.0267721065445192	CCL3/CCL4/CCL3L3/GPR183/CCL20	5
GO:0001704	formation of primary germ layer	7/319	121/18722	0.00471418477458031	0.0269541218474265	KLF4/DUSP2/DUSP1/FN1/KDM6B/CTNNB1/ETS2	7
GO:1904019	epithelial cell apoptotic process	7/319	121/18722	0.00471418477458031	0.0269541218474265	TNFAIP3/ICAM1/TNF/ZFP36/HMOX1/RGCC/THBS1	7
GO:0005996	monosaccharide metabolic process	11/319	257/18722	0.00475441749881652	0.0271464032467149	ATF3/TNF/PGK1/IRS2/PMAIP1/MIDN/SERP1/PFKFB3/SLC2A3/HMGB1/DCXR	11
GO:0044270	cellular nitrogen compound catabolic process	16/319	451/18722	0.00478618765363004	0.0272898993676465	HNRNPM/PDE4B/HNRNPA0/ZFP36/ETF1/LSM6/DDX5/NPM1/HMOX1/YBX3/HNRNPU/SERBP1/TOB1/SSB/YBX1/TYMP	16
GO:0048525	negative regulation of viral process	6/319	92/18722	0.00488463783159074	0.0278126677640852	TNF/ZFP36/SNX3/FCN1/ISG15/IFIT1	6
GO:0007599	hemostasis	10/319	222/18722	0.00490312444836876	0.027840807468569	FN1/PLAUR/TLN1/ANXA5/PLEK/APOE/PF4/FBLN1/THBS1/DGKZ	10
GO:0050817	coagulation	10/319	222/18722	0.00490312444836876	0.027840807468569	FN1/PLAUR/TLN1/ANXA5/PLEK/APOE/PF4/FBLN1/THBS1/DGKZ	10
GO:0051168	nuclear export	8/319	154/18722	0.00496449329938861	0.0281503889017746	IL1B/HNRNPA1/ANP32B/SRSF3/YTHDC1/NPM1/SSB/RPS15	8
GO:0043489	RNA stabilization	5/319	65/18722	0.00498937581933587	0.0281748955951783	HNRNPA0/ZFP36/YBX3/HNRNPU/YBX1	5
GO:0071677	positive regulation of mononuclear cell migration	5/319	65/18722	0.00498937581933587	0.0281748955951783	CCL3/CCL4/TNF/CCL20/HMGB1	5
GO:0072577	endothelial cell apoptotic process	5/319	65/18722	0.00498937581933587	0.0281748955951783	TNFAIP3/ICAM1/TNF/RGCC/THBS1	5
GO:0045927	positive regulation of growth	11/319	259/18722	0.00503468241182769	0.0283917412826113	FN1/CXCR4/VEGFA/PIM1/HBEGF/BASP1/SEMA4D/YBX3/SERP1/S100A8/CSH1	11
GO:0050856	regulation of T cell receptor signaling pathway	4/319	41/18722	0.0050994460691473	0.0286782801508407	PRNP/CD81/GBP1/DGKZ	4
GO:1905521	regulation of macrophage migration	4/319	41/18722	0.0050994460691473	0.0286782801508407	CCL3/CD81/C5AR1/THBS1	4
GO:0019217	regulation of fatty acid metabolic process	6/319	93/18722	0.00514857302935094	0.0288755576039041	IL1B/IRS2/SNCA/PTGS2/NR4A3/APOC1	6
GO:0051591	response to cAMP	6/319	93/18722	0.00514857302935094	0.0288755576039041	FOS/FOSB/JUN/DUSP1/AREG/LDHA	6
GO:1903364	positive regulation of cellular protein catabolic process	8/319	155/18722	0.00515937887252813	0.0288967391620751	TNFAIP3/TRIB1/GABARAP/CD81/SUMO2/RNF19B/APOE/PIAS1	8
GO:0030502	negative regulation of bone mineralization	3/319	21/18722	0.00519085991403965	0.0289154811742778	CCL3/HIF1A/SRGN	3
GO:0032516	positive regulation of phosphoprotein phosphatase activity	3/319	21/18722	0.00519085991403965	0.0289154811742778	PPP1R15A/PPP1R15B/HSP90AB1	3
GO:0046641	positive regulation of alpha-beta T cell proliferation	3/319	21/18722	0.00519085991403965	0.0289154811742778	RIPK2/CD81/HLA-A	3
GO:0071498	cellular response to fluid shear stress	3/319	21/18722	0.00519085991403965	0.0289154811742778	KLF4/PTGS2/KLF2	3
GO:0048511	rhythmic process	12/319	298/18722	0.00527753849432938	0.0293585395807687	JUND/JUN/BHLHE40/NFIL3/KLF10/ID2/DDX5/HNRNPU/CREM/EGR1/EREG/RETN	12
GO:0014015	positive regulation of gliogenesis	5/319	66/18722	0.00532467250791876	0.0294612768237604	IL1B/CXCR4/TNF/ID2/HES1	5
GO:0050918	positive chemotaxis	5/319	66/18722	0.00532467250791876	0.0294612768237604	CXCL8/CCL3/VEGFA/HMGB2/HMGB1	5
GO:1905953	negative regulation of lipid localization	5/319	66/18722	0.00532467250791876	0.0294612768237604	NFKBIA/TNF/IRS2/THBS1/APOC1	5
GO:2000573	positive regulation of DNA biosynthetic process	5/319	66/18722	0.00532467250791876	0.0294612768237604	KLF4/HNRNPA1/CTNNB1/HSP90AB1/RGCC	5
GO:0002042	cell migration involved in sprouting angiogenesis	6/319	94/18722	0.00542281800458652	0.0299237648548391	KLF4/NR4A1/VEGFA/PTGS2/HMOX1/THBS1	6
GO:0019080	viral gene expression	6/319	94/18722	0.00542281800458652	0.0299237648548391	CCL3/JUN/CCL4/ZFP36/CHD1/SSB	6
GO:0046596	regulation of viral entry into host cell	4/319	42/18722	0.00556191330764639	0.030650168374979	SNX3/TRIM22/FCN1/HLA-DRB1	4
GO:0061180	mammary gland epithelium development	5/319	67/18722	0.00567559375689095	0.0312347602872539	HIF1A/AREG/ID2/CEBPB/STAT6	5
GO:0042063	gliogenesis	12/319	301/18722	0.00570401478245851	0.0312436168387891	CCL3/IL1B/CXCR4/TNF/GPR183/AREG/CTNNB1/ID2/ZMIZ1/HES1/C5AR1/S100A8	12
GO:0042886	amide transport	12/319	301/18722	0.00570401478245851	0.0312436168387891	IL1B/PIM3/HIF1A/TNF/IRS2/MIDN/FFAR2/SERP1/IL1RN/S100A8/HLA-DRB1/PPP3CA	12
GO:0036473	cell death in response to oxidative stress	6/319	95/18722	0.00570760307612031	0.0312436168387891	HIF1A/SOD2/MCL1/CTNNB1/PAGE4/NR4A3	6
GO:0050764	regulation of phagocytosis	6/319	95/18722	0.00570760307612031	0.0312436168387891	IL1B/TNF/SNX3/C3/HMGB1/NCKAP1L	6
GO:0032872	regulation of stress-activated MAPK cascade	9/319	192/18722	0.00578133275747305	0.0316051316036858	GADD45B/DUSP1/IL1B/VEGFA/TNF/DNAJA1/RIPK2/PAGE4/HMGB1	9
GO:0032069	regulation of nuclease activity	3/319	22/18722	0.00593551424114117	0.0321911596904108	HMGB2/NPM1/HMGB1	3
GO:0035584	calcium-mediated signaling using intracellular calcium source	3/319	22/18722	0.00593551424114117	0.0321911596904108	PRNP/CCL20/DEFB1	3
GO:0045624	positive regulation of T-helper cell differentiation	3/319	22/18722	0.00593551424114117	0.0321911596904108	NFKBIZ/NLRP3/RIPK2	3
GO:0050860	negative regulation of T cell receptor signaling pathway	3/319	22/18722	0.00593551424114117	0.0321911596904108	PRNP/GBP1/DGKZ	3
GO:0051412	response to corticosterone	3/319	22/18722	0.00593551424114117	0.0321911596904108	FOS/FOSB/CDKN1A	3
GO:0060713	labyrinthine layer morphogenesis	3/319	22/18722	0.00593551424114117	0.0321911596904108	SOCS3/DNAJB6/GRB2	3
GO:1901655	cellular response to ketone	6/319	96/18722	0.00600315828033799	0.032515130026969	KLF4/DDIT4/ICAM1/KLF2/PTGER4/SPP1	6
GO:0002861	regulation of inflammatory response to antigenic stimulus	4/319	43/18722	0.00605155649530287	0.0326482267089109	TNF/CD81/C3/HLA-DRB1	4
GO:0006509	membrane protein ectodomain proteolysis	4/319	43/18722	0.00605155649530287	0.0326482267089109	IL1B/TNF/APOE/TIMP3	4
GO:0045840	positive regulation of mitotic nuclear division	4/319	43/18722	0.00605155649530287	0.0326482267089109	IL1B/EREG/RGCC/IL1A	4
GO:0048565	digestive tract development	7/319	127/18722	0.00612302458621581	0.0329473220863	CXCL8/HIF1A/CDKN1A/TNF/CTNNB1/ID2/HES1	7
GO:0051224	negative regulation of protein transport	7/319	127/18722	0.00612302458621581	0.0329473220863	IL1B/PIM3/MIDN/SNX3/ERP29/APOE/PPP3CA	7
GO:0010596	negative regulation of endothelial cell migration	6/319	97/18722	0.00630971324112451	0.033907491678775	KLF4/TNF/RGCC/APOE/HMGB1/THBS1	6
GO:0070302	regulation of stress-activated protein kinase signaling cascade	9/319	195/18722	0.00638081327476708	0.0342246508930274	GADD45B/DUSP1/IL1B/VEGFA/TNF/DNAJA1/RIPK2/PAGE4/HMGB1	9
GO:0035303	regulation of dephosphorylation	7/319	128/18722	0.00638538244586525	0.0342246508930274	PPP1R15A/PPP1R15B/TNF/SEMA4D/HSP90AB1/PLEK/NCKAP1L	7
GO:1901224	positive regulation of NIK/NF-kappaB signaling	5/319	69/18722	0.00642580443282458	0.034396460967893	IL1B/TNF/LIMS1/NMI/HMGB1	5
GO:0150076	neuroinflammatory response	4/319	44/18722	0.00656904635345818	0.0351174896736886	CCL3/IL1B/TNF/PTGS2	4
GO:0006006	glucose metabolic process	9/319	196/18722	0.00659090981243314	0.0351886106998865	ATF3/TNF/PGK1/IRS2/PMAIP1/MIDN/SERP1/HMGB1/DCXR	9
GO:0019439	aromatic compound catabolic process	16/319	467/18722	0.00662383287069123	0.0352309385322539	HNRNPM/PDE4B/HNRNPA0/ZFP36/ETF1/LSM6/DDX5/NPM1/HMOX1/YBX3/HNRNPU/SERBP1/TOB1/SSB/YBX1/TYMP	16
GO:1902882	regulation of response to oxidative stress	6/319	98/18722	0.00662749704087151	0.0352309385322539	HIF1A/SOD2/MCL1/CTNNB1/PAGE4/NR4A3	6
GO:1904029	regulation of cyclin-dependent protein kinase activity	6/319	98/18722	0.00662749704087151	0.0352309385322539	TNFAIP3/CDKN1A/CCNL1/HSP90AB1/RGCC/HERC5	6
GO:0032271	regulation of protein polymerization	10/319	232/18722	0.00663311759279118	0.0352309385322539	TMSB4X/ICAM1/MAPRE1/GRB2/MYADM/BRK1/VDAC2/SNCA/COTL1/NCKAP1L	10
GO:0034250	positive regulation of cellular amide metabolic process	8/319	162/18722	0.00669211639797163	0.035452693958842	PPP1R15A/TNF/NPM1/YBX3/SERP1/TOB1/RPL5/THBS1	8
GO:0060759	regulation of response to cytokine stimulus	8/319	162/18722	0.00669211639797163	0.035452693958842	TNFAIP3/KLF4/CXCR4/HIF1A/RIPK2/HSP90AB1/IL1RN/ISG15	8
GO:0002052	positive regulation of neuroblast proliferation	3/319	23/18722	0.00674079219110789	0.0354819419944232	HIF1A/VEGFA/CTNNB1	3
GO:0002082	regulation of oxidative phosphorylation	3/319	23/18722	0.00674079219110789	0.0354819419944232	PPIF/COX7A2L/SNCA	3
GO:0035994	response to muscle stretch	3/319	23/18722	0.00674079219110789	0.0354819419944232	NFKBIA/FOS/CTNNB1	3
GO:0072677	eosinophil migration	3/319	23/18722	0.00674079219110789	0.0354819419944232	CCL3/CCL4/PTGER4	3
GO:1902410	mitotic cytokinetic process	3/319	23/18722	0.00674079219110789	0.0354819419944232	CHMP1B/CHMP2B/CHMP5	3
GO:0006417	regulation of translation	16/319	468/18722	0.00675534612143273	0.0355130791626726	PPP1R15A/NCL/PPP1R15B/TNF/EIF1B/ZNF706/ZFP36/ETF1/NPM1/EIF1/YBX3/SERP1/TOB1/YBX1/RPL5/THBS1	16
GO:0043467	regulation of generation of precursor metabolites and energy	7/319	130/18722	0.00693510532305704	0.0364115172197797	DDIT4/HIF1A/PPIF/COX7A2L/IRS2/SNCA/HMGB1	7
GO:0002444	myeloid leukocyte mediated immunity	6/319	99/18722	0.00695673809265487	0.0364320385973302	CCL3/TREM1/HMOX1/SERPINB9/NR4A3/C3	6
GO:0033209	tumor necrosis factor-mediated signaling pathway	6/319	99/18722	0.00695673809265487	0.0364320385973302	NFKBIA/TNFAIP3/TMSB4X/BIRC3/TNF/LIMS1	6
GO:0010824	regulation of centrosome duplication	4/319	45/18722	0.00711503539452835	0.0371663411777714	CHMP1B/CHMP2B/CHMP5/NPM1	4
GO:0035305	negative regulation of dephosphorylation	4/319	45/18722	0.00711503539452835	0.0371663411777714	PPP1R15A/TNF/SEMA4D/NCKAP1L	4
GO:0051047	positive regulation of secretion	12/319	310/18722	0.00714976452610126	0.0373003578258912	IL1B/HIF1A/IRS2/HCAR2/SNCA/SERP1/RGCC/IL1A/SPP1/S100A8/RETN/HLA-DRB1	12
GO:2000058	regulation of ubiquitin-dependent protein catabolic process	8/319	164/18722	0.00718754201721989	0.0374499179122826	TRIB1/GABARAP/HSP90AB1/SUMO2/RNF19B/RPL23/RPL5/PIAS1	8
GO:0046683	response to organophosphorus	7/319	131/18722	0.00722278019087701	0.0375858852717663	FOS/FOSB/JUN/DUSP1/AREG/LDHA/PTGS2	7
GO:0045824	negative regulation of innate immune response	5/319	71/18722	0.00724296260248078	0.0376432607570145	TNFAIP3/NMI/SERPINB9/ISG15/HLA-A	5
GO:0045807	positive regulation of endocytosis	6/319	100/18722	0.00729766401367746	0.0378796676265506	VEGFA/SNCA/APOE/C3/PPP3CA/NCKAP1L	6
GO:0001911	negative regulation of leukocyte mediated cytotoxicity	3/319	24/18722	0.00760785858566296	0.0391438130734173	SERPINB9/HLA-A/NCKAP1L	3
GO:0002922	positive regulation of humoral immune response	3/319	24/18722	0.00760785858566296	0.0391438130734173	IL1B/TNF/C3	3
GO:0045649	regulation of macrophage differentiation	3/319	24/18722	0.00760785858566296	0.0391438130734173	TRIB1/ID2/PF4	3
GO:0051000	positive regulation of nitric-oxide synthase activity	3/319	24/18722	0.00760785858566296	0.0391438130734173	HIF1A/TNF/APOE	3
GO:0070935	3'-UTR-mediated mRNA stabilization	3/319	24/18722	0.00760785858566296	0.0391438130734173	HNRNPA0/ZFP36/YBX3	3
GO:0090023	positive regulation of neutrophil chemotaxis	3/319	24/18722	0.00760785858566296	0.0391438130734173	CXCL8/C5AR1/NCKAP1L	3
GO:2001026	regulation of endothelial cell chemotaxis	3/319	24/18722	0.00760785858566296	0.0391438130734173	TMSB4X/VEGFA/THBS1	3
GO:0019318	hexose metabolic process	10/319	237/18722	0.00765922507915347	0.0393097057433208	ATF3/TNF/PGK1/IRS2/PMAIP1/MIDN/SERP1/PFKFB3/HMGB1/DCXR	10
GO:0031334	positive regulation of protein-containing complex assembly	10/319	237/18722	0.00765922507915347	0.0393097057433208	ICAM1/VEGFA/TNF/MAPRE1/GRB2/BRK1/SNCA/PLEK/ISG15/NCKAP1L	10
GO:0070227	lymphocyte apoptotic process	5/319	72/18722	0.007677553918618	0.0393546435903224	HIF1A/IRS2/BCL6/TSC22D3/RPS6	5
GO:2000107	negative regulation of leukocyte apoptotic process	4/319	46/18722	0.00769015743761404	0.0393701584383951	HIF1A/IRS2/BCL6/TSC22D3	4
GO:0010565	regulation of cellular ketone metabolic process	7/319	133/18722	0.00782453110854554	0.0399089917955716	IL1B/IRS2/SNCA/PTGS2/EGR1/NR4A3/APOC1	7
GO:0010595	positive regulation of endothelial cell migration	7/319	133/18722	0.00782453110854554	0.0399089917955716	TMSB4X/HIF1A/VEGFA/PTGS2/HMOX1/HMGB1/THBS1	7
GO:0046887	positive regulation of hormone secretion	7/319	133/18722	0.00782453110854554	0.0399089917955716	HIF1A/IRS2/HCAR2/SERP1/SPP1/RETN/HLA-DRB1	7
GO:0007254	JNK cascade	8/319	167/18722	0.00798195209994439	0.0406614685041777	GADD45B/TRIB1/IL1B/TNF/DNAJA1/RIPK2/PTGER4/HMGB1	8
GO:1902106	negative regulation of leukocyte differentiation	6/319	102/18722	0.00801547620312951	0.0407817112265661	CCL3/TRIB1/CTNNB1/BCL6/ID2/HMGB1	6
GO:0042274	ribosomal small subunit biogenesis	5/319	73/18722	0.00812996203944584	0.0412565792117544	LSM6/NPM1/RPS15/RPS28/RPS6	5
GO:0008277	regulation of G protein-coupled receptor signaling pathway	7/319	134/18722	0.00813891650224588	0.0412565792117544	CXCL8/PDE4B/RGS1/RGS10/SNCA/PLEK/C3	7
GO:0061041	regulation of wound healing	7/319	134/18722	0.00813891650224588	0.0412565792117544	TNFAIP3/CXCR4/TNF/HBEGF/APOE/HMGB1/THBS1	7
GO:0097300	programmed necrotic cell death	4/319	47/18722	0.00829502717258347	0.0419444731937154	BIRC3/PPIF/TNF/YBX3	4
GO:1900744	regulation of p38MAPK cascade	4/319	47/18722	0.00829502717258347	0.0419444731937154	GADD45B/DUSP1/IL1B/VEGFA	4
GO:0014013	regulation of gliogenesis	6/319	103/18722	0.00839281260710201	0.0423347885003636	IL1B/CXCR4/TNF/CTNNB1/ID2/HES1	6
GO:0032760	positive regulation of tumor necrosis factor production	6/319	103/18722	0.00839281260710201	0.0423347885003636	CCL3/RIPK2/IL1A/PF4/HMGB1/THBS1	6
GO:0071383	cellular response to steroid hormone stimulus	9/319	204/18722	0.00846871796306898	0.0426653180712948	DDIT4/ICAM1/YWHAH/ZFP36/DNAJA1/DDX5/HNRNPU/ZMIZ1/NR4A3	9
GO:0045324	late endosome to vacuole transport	3/319	25/18722	0.00853776345432431	0.0428646304714938	CHMP1B/CHMP2B/CHMP5	3
GO:1903798	regulation of production of miRNAs involved in gene silencing by miRNA	3/319	25/18722	0.00853776345432431	0.0428646304714938	TNF/DDX5/PPP3CA	3
GO:0010631	epithelial cell migration	13/319	357/18722	0.00853956029096411	0.0428646304714938	KLF4/TMSB4X/NR4A1/HIF1A/VEGFA/TNF/HBEGF/PTGS2/HMOX1/RGCC/APOE/HMGB1/THBS1	13
GO:0021700	developmental maturation	11/319	280/18722	0.00883765419201129	0.0442675420182439	NR4A2/HIF1A/VEGFA/CDKN1A/CTNNB1/SEMA4D/KLF2/EREG/HES1/DEFB1/C3	11
GO:0007259	receptor signaling pathway via JAK-STAT	8/319	170/18722	0.00884058671782492	0.0442675420182439	SOCS3/TNF/OSM/NMI/HES1/STAT6/CSH1/PIAS1	8
GO:0051052	regulation of DNA metabolic process	13/319	359/18722	0.00892340545240684	0.0446278829864289	KLF4/DUSP1/HNRNPA1/CDKN1A/CTNNB1/BCL6/NPM1/DEK/HSP90AB1/HNRNPU/RGCC/HMGB1/STAT6	13
GO:0007249	I-kappaB kinase/NF-kappaB signaling	11/319	281/18722	0.00906260962005701	0.0452690013949628	NFKBIA/TNFAIP3/IL1B/BIRC3/TNF/LITAF/CTNNB1/RIPK2/HMOX1/TRIM22/HLA-DRB1	11
GO:0045913	positive regulation of carbohydrate metabolic process	5/319	75/18722	0.00908962708440852	0.0453488555145673	HIF1A/IRS2/PMAIP1/SNCA/HMGB1	5
GO:0090132	epithelium migration	13/319	360/18722	0.00912034431649974	0.0453697676243556	KLF4/TMSB4X/NR4A1/HIF1A/VEGFA/TNF/HBEGF/PTGS2/HMOX1/RGCC/APOE/HMGB1/THBS1	13
GO:0006986	response to unfolded protein	7/319	137/18722	0.00913796341351653	0.0453697676243556	ATF3/PPP1R15A/PPP1R15B/DNAJA1/HSP90AB1/SERP1/THBS1	7
GO:0030879	mammary gland development	7/319	137/18722	0.00913796341351653	0.0453697676243556	HIF1A/VEGFA/AREG/IRS2/ID2/CEBPB/STAT6	7
GO:0055123	digestive system development	7/319	137/18722	0.00913796341351653	0.0453697676243556	CXCL8/HIF1A/CDKN1A/TNF/CTNNB1/ID2/HES1	7
GO:0016064	immunoglobulin mediated immune response	9/319	207/18722	0.00926884098402754	0.0459640594515527	TNF/BCL6/CD81/HLA-DPB1/HLA-DQA1/C3/HLA-DRA/STAT6/HLA-DRB1	9
GO:1903532	positive regulation of secretion by cell	11/319	282/18722	0.00929197015858652	0.0460232401469267	IL1B/HIF1A/IRS2/HCAR2/SNCA/SERP1/RGCC/IL1A/SPP1/RETN/HLA-DRB1	11
GO:0002221	pattern recognition receptor signaling pathway	8/319	172/18722	0.00945019088049782	0.0463269981558649	NFKBIA/TNFAIP3/BIRC3/RIPK2/FFAR2/NMI/FCN1/HMGB1	8
GO:0055076	transition metal ion homeostasis	7/319	138/18722	0.00949012146633053	0.0463269981558649	HIF1A/SLC25A37/PRNP/FTH1/HMOX1/MT2A/S100A8	7
GO:0002407	dendritic cell chemotaxis	3/319	26/18722	0.00953144654873288	0.0463269981558649	CXCR4/GPR183/HMGB1	3
GO:0002418	immune response to tumor cell	3/319	26/18722	0.00953144654873288	0.0463269981558649	HLA-A/HMGB1/HLA-DRB1	3
GO:0006706	steroid catabolic process	3/319	26/18722	0.00953144654873288	0.0463269981558649	YWHAH/SPP1/APOE	3
GO:0032515	negative regulation of phosphoprotein phosphatase activity	3/319	26/18722	0.00953144654873288	0.0463269981558649	PPP1R15A/TNF/NCKAP1L	3
GO:0045672	positive regulation of osteoclast differentiation	3/319	26/18722	0.00953144654873288	0.0463269981558649	FOS/TNF/KLF10	3
GO:0046697	decidualization	3/319	26/18722	0.00953144654873288	0.0463269981558649	JUNB/PTGS2/SPP1	3
GO:0046755	viral budding	3/319	26/18722	0.00953144654873288	0.0463269981558649	CHMP1B/CHMP2B/CHMP5	3
GO:0060669	embryonic placenta morphogenesis	3/319	26/18722	0.00953144654873288	0.0463269981558649	SOCS3/DNAJB6/GRB2	3
GO:0070920	regulation of production of small RNA involved in gene silencing by RNA	3/319	26/18722	0.00953144654873288	0.0463269981558649	TNF/DDX5/PPP3CA	3
GO:1905523	positive regulation of macrophage migration	3/319	26/18722	0.00953144654873288	0.0463269981558649	CCL3/C5AR1/THBS1	3
GO:0001913	T cell mediated cytotoxicity	4/319	49/18722	0.00959637053825792	0.0463269981558649	HLA-A/HLA-DRA/HLA-DRB1/NCKAP1L	4
GO:0043457	regulation of cellular respiration	4/319	49/18722	0.00959637053825792	0.0463269981558649	HIF1A/PPIF/COX7A2L/SNCA	4
GO:0046605	regulation of centrosome cycle	4/319	49/18722	0.00959637053825792	0.0463269981558649	CHMP1B/CHMP2B/CHMP5/NPM1	4
GO:0060964	regulation of gene silencing by miRNA	4/319	49/18722	0.00959637053825792	0.0463269981558649	TNF/ZFP36/DDX5/PPP3CA	4
GO:0072091	regulation of stem cell proliferation	4/319	49/18722	0.00959637053825792	0.0463269981558649	PIM1/HMGB2/HNRNPU/FBLN1	4
GO:0014823	response to activity	5/319	76/18722	0.00959757087456019	0.0463269981558649	METRNL/CXCR4/HIF1A/KDM6B/SOD2	5
GO:0071426	ribonucleoprotein complex export from nucleus	5/319	76/18722	0.00959757087456019	0.0463269981558649	SRSF3/YTHDC1/NPM1/SSB/RPS15	5
GO:0035821	modulation of process of other organism	6/319	106/18722	0.00960121683989221	0.0463269981558649	CCL3/JUN/CCL4/SERPINB9/CHD1/APOE	6
GO:0071887	leukocyte apoptotic process	6/319	106/18722	0.00960121683989221	0.0463269981558649	HIF1A/IRS2/BCL6/HCAR2/TSC22D3/RPS6	6
GO:1903707	negative regulation of hemopoiesis	6/319	106/18722	0.00960121683989221	0.0463269981558649	CCL3/TRIB1/CTNNB1/BCL6/ID2/HMGB1	6
GO:0051341	regulation of oxidoreductase activity	6/319	107/18722	0.01003021736295	0.0482836341675499	IL1B/HIF1A/TNF/SNCA/IL1A/APOE	6
GO:1903557	positive regulation of tumor necrosis factor superfamily cytokine production	6/319	107/18722	0.01003021736295	0.0482836341675499	CCL3/RIPK2/IL1A/PF4/HMGB1/THBS1	6
GO:0048639	positive regulation of developmental growth	8/319	174/18722	0.0100905896065511	0.0484557545656813	FN1/CXCR4/VEGFA/PIM1/BASP1/SEMA4D/YBX3/SERP1	8
GO:0000380	alternative mRNA splicing, via spliceosome	5/319	77/18722	0.0101247047419972	0.0484557545656813	HNRNPA1/HNRNPM/YTHDC1/DDX5/HNRNPU	5
GO:0010827	regulation of glucose transmembrane transport	5/319	77/18722	0.0101247047419972	0.0484557545656813	IL1B/TNF/IRS2/NR4A3/C3	5
GO:0071166	ribonucleoprotein complex localization	5/319	77/18722	0.0101247047419972	0.0484557545656813	SRSF3/YTHDC1/NPM1/SSB/RPS15	5
GO:0019724	B cell mediated immunity	9/319	210/18722	0.0101249071203893	0.0484557545656813	TNF/BCL6/CD81/HLA-DPB1/HLA-DQA1/C3/HLA-DRA/STAT6/HLA-DRB1	9
GO:0090130	tissue migration	13/319	365/18722	0.0101567563447334	0.0485516573641848	KLF4/TMSB4X/NR4A1/HIF1A/VEGFA/TNF/HBEGF/PTGS2/HMOX1/RGCC/APOE/HMGB1/THBS1	13
GO:0031333	negative regulation of protein-containing complex assembly	7/319	140/18722	0.010224068349205	0.0488166608403969	TMSB4X/MAPRE1/MYADM/VDAC2/SNCA/PTGER4/HMGB1	7
GO:0007080	mitotic metaphase plate congression	4/319	50/18722	0.0102939746156394	0.0490934218618256	CHMP1B/CHMP2B/CHMP5/HNRNPU	4
GO:0021537	telencephalon development	10/319	248/18722	0.0103455881118704	0.0492824017704509	BCL2A1/PHACTR1/CXCR4/HIF1A/KDM6B/CTNNB1/ID2/TMEM14B/ZMIZ1/HES1	10
GO:0050807	regulation of synapse organization	9/319	211/18722	0.0104230966569626	0.0495941555055245	TNF/CHMP2B/PRNP/SRGN/SNCA/SEMA4D/TUBA1A/APOE/TUBB	9
GO:0002832	negative regulation of response to biotic stimulus	6/319	108/18722	0.0104726803409993	0.0497724726957782	TNFAIP3/TRIB1/NMI/SERPINB9/ISG15/HLA-A	6
GO:0002719	negative regulation of cytokine production involved in immune response	3/319	27/18722	0.010589741721399	0.0500596185282638	TNF/BCL6/HMOX1	3
GO:0007263	nitric oxide mediated signal transduction	3/319	27/18722	0.010589741721399	0.0500596185282638	VEGFA/APOE/THBS1	3
GO:0060333	interferon-gamma-mediated signaling pathway	3/319	27/18722	0.010589741721399	0.0500596185282638	IFNGR2/NMI/HSP90AB1	3
GO:0071624	positive regulation of granulocyte chemotaxis	3/319	27/18722	0.010589741721399	0.0500596185282638	CXCL8/C5AR1/NCKAP1L	3
GO:0140694	non-membrane-bounded organelle assembly	13/319	367/18722	0.0105961866959171	0.0500596185282638	CHMP1B/TNF/CHMP2B/MAPRE1/CHMP5/SBDS/NPM1/HNRNPU/RPL3/RPS15/RPS28/RPL5/TUBB	13
GO:1903038	negative regulation of leukocyte cell-cell adhesion	7/319	141/18722	0.0106061609676764	0.0500596185282638	KLF4/BCL6/PRNP/CEBPB/HMGB1/HLA-DRB1/NCKAP1L	7
GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	10/319	249/18722	0.0106213573607445	0.0500738533371795	TNFAIP3/IL1B/BIRC3/TNF/LITAF/CTNNB1/RIPK2/HMOX1/TRIM22/HLA-DRB1	10
GO:0090049	regulation of cell migration involved in sprouting angiogenesis	5/319	78/18722	0.0106713587725295	0.0502519540823239	KLF4/VEGFA/PTGS2/HMOX1/THBS1	5
GO:0009749	response to glucose	9/319	212/18722	0.0107278469881706	0.0504601590027108	PIM3/HIF1A/ICAM1/LDHA/IRS2/EGR1/THBS1/HLA-DRB1/PPP3CA	9
GO:0010634	positive regulation of epithelial cell migration	8/319	176/18722	0.0107626804535679	0.0505661478224202	TMSB4X/HIF1A/VEGFA/HBEGF/PTGS2/HMOX1/HMGB1/THBS1	8
GO:0014009	glial cell proliferation	4/319	51/18722	0.0110235867125152	0.0516149942769361	IL1B/TNF/AREG/HES1	4
GO:0045668	negative regulation of osteoblast differentiation	4/319	51/18722	0.0110235867125152	0.0516149942769361	TNF/AREG/SEMA4D/TOB1	4
GO:0071622	regulation of granulocyte chemotaxis	4/319	51/18722	0.0110235867125152	0.0516149942769361	CXCL8/C5AR1/THBS1/NCKAP1L	4
GO:0032272	negative regulation of protein polymerization	5/319	79/18722	0.0112378573298606	0.0525583975916461	TMSB4X/MAPRE1/MYADM/VDAC2/SNCA	5
GO:0048638	regulation of developmental growth	12/319	330/18722	0.011392738544691	0.0531903285585894	FN1/CXCR4/VEGFA/CDKN1A/PIM1/BASP1/SEMA4D/YBX3/SERP1/PLAC8/SPP1/APOE	12
GO:0002698	negative regulation of immune effector process	6/319	110/18722	0.0113988517295347	0.0531903285585894	TNF/BCL6/HMOX1/SERPINB9/HLA-A/NCKAP1L	6
GO:0006109	regulation of carbohydrate metabolic process	8/319	178/18722	0.0114673577993588	0.0534493286997322	DDIT4/HIF1A/IRS2/PMAIP1/MIDN/SNCA/PLEK/HMGB1	8
GO:0016236	macroautophagy	11/319	291/18722	0.0115636281089405	0.0538370047065167	HIF1A/BNIP3L/GABARAPL1/CHMP2B/MAP1LC3B/GABARAP/UFC1/VMP1/RIPK2/HMOX1/ATP6V1B2	11
GO:0032607	interferon-alpha production	3/319	28/18722	0.0117133811724128	0.0539308336307559	RIPK2/NMI/HMGB1	3
GO:0032647	regulation of interferon-alpha production	3/319	28/18722	0.0117133811724128	0.0539308336307559	RIPK2/NMI/HMGB1	3
GO:0045589	regulation of regulatory T cell differentiation	3/319	28/18722	0.0117133811724128	0.0539308336307559	BCL6/HLA-DRA/HLA-DRB1	3
GO:0061082	myeloid leukocyte cytokine production	3/319	28/18722	0.0117133811724128	0.0539308336307559	BCL6/HMOX1/NR4A3	3
GO:0090200	positive regulation of release of cytochrome c from mitochondria	3/319	28/18722	0.0117133811724128	0.0539308336307559	PLAUR/PPIF/PMAIP1	3
GO:1902624	positive regulation of neutrophil migration	3/319	28/18722	0.0117133811724128	0.0539308336307559	CXCL8/C5AR1/NCKAP1L	3
GO:1903672	positive regulation of sprouting angiogenesis	3/319	28/18722	0.0117133811724128	0.0539308336307559	KLF4/VEGFA/HMGB1	3
GO:0002218	activation of innate immune response	4/319	52/18722	0.0117857208846748	0.0539308336307559	FFAR2/FCN1/MNDA/HMGB1	4
GO:0043277	apoptotic cell clearance	4/319	52/18722	0.0117857208846748	0.0539308336307559	FCN1/C3/HMGB1/THBS1	4
GO:0043392	negative regulation of DNA binding	4/319	52/18722	0.0117857208846748	0.0539308336307559	NFKBIA/JUN/TMSB4X/HMOX1	4
GO:0060147	regulation of posttranscriptional gene silencing	4/319	52/18722	0.0117857208846748	0.0539308336307559	TNF/ZFP36/DDX5/PPP3CA	4
GO:0046718	viral entry into host cell	7/319	144/18722	0.0118147241359034	0.0539308336307559	CXCR4/ICAM1/SNX3/CD81/TRIM22/FCN1/HLA-DRB1	7
GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	2/319	10/18722	0.0118986295556058	0.0539308336307559	ICAM1/CD81	2
GO:0010998	regulation of translational initiation by eIF2 alpha phosphorylation	2/319	10/18722	0.0118986295556058	0.0539308336307559	PPP1R15B/NPM1	2
GO:0015911	long-chain fatty acid import across plasma membrane	2/319	10/18722	0.0118986295556058	0.0539308336307559	IRS2/THBS1	2
GO:0032070	regulation of deoxyribonuclease activity	2/319	10/18722	0.0118986295556058	0.0539308336307559	NPM1/HMGB1	2
GO:0033080	immature T cell proliferation in thymus	2/319	10/18722	0.0118986295556058	0.0539308336307559	IL1B/IL1A	2
GO:0035747	natural killer cell chemotaxis	2/319	10/18722	0.0118986295556058	0.0539308336307559	CCL3/CCL4	2
GO:0072378	blood coagulation, fibrin clot formation	2/319	10/18722	0.0118986295556058	0.0539308336307559	FN1/FBLN1	2
GO:0097084	vascular associated smooth muscle cell development	2/319	10/18722	0.0118986295556058	0.0539308336307559	VEGFA/HES1	2
GO:0097278	complement-dependent cytotoxicity	2/319	10/18722	0.0118986295556058	0.0539308336307559	HSP90AB1/C3	2
GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin	2/319	10/18722	0.0118986295556058	0.0539308336307559	VEGFA/RGCC	2
GO:2000425	regulation of apoptotic cell clearance	2/319	10/18722	0.0118986295556058	0.0539308336307559	C3/HMGB1	2
GO:2000434	regulation of protein neddylation	2/319	10/18722	0.0118986295556058	0.0539308336307559	HIF1A/RPL5	2
GO:0071897	DNA biosynthetic process	8/319	180/18722	0.0122055117175895	0.0552608575671922	KLF4/DUSP1/HNRNPA1/CDKN1A/CTNNB1/HSP90AB1/HNRNPU/RGCC	8
GO:0061351	neural precursor cell proliferation	7/319	145/18722	0.0122388382040174	0.0553507853209193	HIF1A/VEGFA/CTNNB1/ID2/TMEM14B/NAP1L1/C5AR1	7
GO:0010633	negative regulation of epithelial cell migration	6/319	112/18722	0.0123814267616542	0.0558735386276831	KLF4/TNF/RGCC/APOE/HMGB1/THBS1	6
GO:0000422	autophagy of mitochondrion	5/319	81/18722	0.012431655680869	0.0558735386276831	HIF1A/BNIP3L/GABARAPL1/MAP1LC3B/GABARAP	5
GO:0048708	astrocyte differentiation	5/319	81/18722	0.012431655680869	0.0558735386276831	TNF/ID2/HES1/C5AR1/S100A8	5
GO:0061726	mitochondrion disassembly	5/319	81/18722	0.012431655680869	0.0558735386276831	HIF1A/BNIP3L/GABARAPL1/MAP1LC3B/GABARAP	5
GO:2000106	regulation of leukocyte apoptotic process	5/319	81/18722	0.012431655680869	0.0558735386276831	HIF1A/IRS2/BCL6/HCAR2/TSC22D3	5
GO:0042113	B cell activation	12/319	334/18722	0.012435973691153	0.0558735386276831	TNFAIP3/KLF6/CDKN1A/GPR183/SAMSN1/IRS2/BCL6/ID2/CD81/MNDA/STAT6/NCKAP1L	12
GO:0001541	ovarian follicle development	4/319	53/18722	0.0125808703462791	0.0559425728284962	ICAM1/VEGFA/CEBPB/EREG	4
GO:0002707	negative regulation of lymphocyte mediated immunity	4/319	53/18722	0.0125808703462791	0.0559425728284962	BCL6/SERPINB9/HLA-A/NCKAP1L	4
GO:0008347	glial cell migration	4/319	53/18722	0.0125808703462791	0.0559425728284962	CCL3/GPR183/CTNNB1/ZMIZ1	4
GO:0045744	negative regulation of G protein-coupled receptor signaling pathway	4/319	53/18722	0.0125808703462791	0.0559425728284962	CXCL8/PDE4B/SNCA/PLEK	4
GO:0051438	regulation of ubiquitin-protein transferase activity	4/319	53/18722	0.0125808703462791	0.0559425728284962	RPL23/RPS15/RPS20/RPL5	4
GO:0060966	regulation of gene silencing by RNA	4/319	53/18722	0.0125808703462791	0.0559425728284962	TNF/ZFP36/DDX5/PPP3CA	4
GO:0008361	regulation of cell size	8/319	181/18722	0.0125874190869275	0.0559425728284962	FN1/VEGFA/NPM1/SEMA4D/HSP90AB1/PLEK/SPP1/APOE	8
GO:0032640	tumor necrosis factor production	8/319	181/18722	0.0125874190869275	0.0559425728284962	TNFAIP3/CCL3/ZFP36/RIPK2/IL1A/PF4/HMGB1/THBS1	8
GO:0032680	regulation of tumor necrosis factor production	8/319	181/18722	0.0125874190869275	0.0559425728284962	TNFAIP3/CCL3/ZFP36/RIPK2/IL1A/PF4/HMGB1/THBS1	8
GO:0097696	receptor signaling pathway via STAT	8/319	181/18722	0.0125874190869275	0.0559425728284962	SOCS3/TNF/OSM/NMI/HES1/STAT6/CSH1/PIAS1	8
GO:0010675	regulation of cellular carbohydrate metabolic process	7/319	146/18722	0.0126738289080191	0.0562657782298774	DDIT4/IRS2/PMAIP1/MIDN/SNCA/PLEK/HMGB1	7
GO:0050803	regulation of synapse structure or activity	9/319	218/18722	0.0126989459388219	0.0563164689908271	TNF/CHMP2B/PRNP/SRGN/SNCA/SEMA4D/TUBA1A/APOE/TUBB	9
GO:0044344	cellular response to fibroblast growth factor stimulus	6/319	113/18722	0.0128943860974072	0.0570368077659362	CXCL8/NR4A1/ZFP36/CTNNB1/SNCA/THBS1	6
GO:0001916	positive regulation of T cell mediated cytotoxicity	3/319	29/18722	0.0129029995675798	0.0570368077659362	HLA-A/HLA-DRA/HLA-DRB1	3
GO:1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	3/319	29/18722	0.0129029995675798	0.0570368077659362	HIF1A/SOD2/MCL1	3
GO:0001706	endoderm formation	4/319	54/18722	0.0134095073172675	0.0590140259530418	DUSP2/DUSP1/FN1/CTNNB1	4
GO:0070228	regulation of lymphocyte apoptotic process	4/319	54/18722	0.0134095073172675	0.0590140259530418	HIF1A/IRS2/BCL6/TSC22D3	4
GO:2000179	positive regulation of neural precursor cell proliferation	4/319	54/18722	0.0134095073172675	0.0590140259530418	HIF1A/VEGFA/CTNNB1/NAP1L1	4
GO:0021987	cerebral cortex development	6/319	114/18722	0.0134220662286777	0.0590140259530418	BCL2A1/PHACTR1/HIF1A/CTNNB1/TMEM14B/ZMIZ1	6
GO:1903008	organelle disassembly	6/319	114/18722	0.0134220662286777	0.0590140259530418	HIF1A/BNIP3L/GABARAPL1/MAP1LC3B/GABARAP/UFC1	6
GO:0014074	response to purine-containing compound	7/319	148/18722	0.0135770258436237	0.0596315739777107	FOS/FOSB/JUN/DUSP1/AREG/LDHA/PTGS2	7
GO:1903050	regulation of proteolysis involved in cellular protein catabolic process	9/319	221/18722	0.0137800238543977	0.0604585678393052	TRIB1/GABARAP/HSP90AB1/SUMO2/RNF19B/RPL23/APOE/RPL5/PIAS1	9
GO:0046916	cellular transition metal ion homeostasis	6/319	115/18722	0.0139646687554501	0.0611415021485518	HIF1A/PRNP/FTH1/HMOX1/MT2A/S100A8	6
GO:0015931	nucleobase-containing compound transport	9/319	222/18722	0.0141551041109905	0.0611415021485518	HNRNPA1/SRSF3/ZFP36/SRSF7/YTHDC1/NPM1/MX2/SSB/YBX1	9
GO:0007176	regulation of epidermal growth factor-activated receptor activity	3/319	30/18722	0.0141591380313571	0.0611415021485518	HBEGF/AREG/EREG	3
GO:0036258	multivesicular body assembly	3/319	30/18722	0.0141591380313571	0.0611415021485518	CHMP1B/CHMP2B/CHMP5	3
GO:0043032	positive regulation of macrophage activation	3/319	30/18722	0.0141591380313571	0.0611415021485518	JUND/CCL3/THBS1	3
GO:0045940	positive regulation of steroid metabolic process	3/319	30/18722	0.0141591380313571	0.0611415021485518	TNF/APOE/APOC1	3
GO:0050858	negative regulation of antigen receptor-mediated signaling pathway	3/319	30/18722	0.0141591380313571	0.0611415021485518	PRNP/GBP1/DGKZ	3
GO:0060674	placenta blood vessel development	3/319	30/18722	0.0141591380313571	0.0611415021485518	SOCS3/JUNB/HES1	3
GO:0070168	negative regulation of biomineral tissue development	3/319	30/18722	0.0141591380313571	0.0611415021485518	CCL3/HIF1A/SRGN	3
GO:0070498	interleukin-1-mediated signaling pathway	3/319	30/18722	0.0141591380313571	0.0611415021485518	IL1B/EGR1/IL1RN	3
GO:1903579	negative regulation of ATP metabolic process	3/319	30/18722	0.0141591380313571	0.0611415021485518	DDIT4/PPIF/SNCA	3
GO:0002040	sprouting angiogenesis	8/319	185/18722	0.0142031456822984	0.0611415021485518	KLF4/NR4A1/VEGFA/PTGS2/KLF2/HMOX1/HMGB1/THBS1	8
GO:0010676	positive regulation of cellular carbohydrate metabolic process	4/319	55/18722	0.0142720829040341	0.0611415021485518	IRS2/PMAIP1/SNCA/HMGB1	4
GO:0061098	positive regulation of protein tyrosine kinase activity	4/319	55/18722	0.0142720829040341	0.0611415021485518	HBEGF/AREG/PRNP/EREG	4
GO:1905517	macrophage migration	4/319	55/18722	0.0142720829040341	0.0611415021485518	CCL3/CD81/C5AR1/THBS1	4
GO:0006405	RNA export from nucleus	5/319	84/18722	0.0143789457848214	0.0611415021485518	HNRNPA1/SRSF3/YTHDC1/NPM1/SSB	5
GO:0006970	response to osmotic stress	5/319	84/18722	0.0143789457848214	0.0611415021485518	TNF/PTGS2/HSP90AB1/YBX3/TSC22D3	5
GO:0032370	positive regulation of lipid transport	5/319	84/18722	0.0143789457848214	0.0611415021485518	NFKBIA/IL1B/SPP1/APOE/RETN	5
GO:0033483	gas homeostasis	2/319	11/18722	0.0143804317461382	0.0611415021485518	HIF1A/SOD2	2
GO:0036490	regulation of translation in response to endoplasmic reticulum stress	2/319	11/18722	0.0143804317461382	0.0611415021485518	PPP1R15A/PPP1R15B	2
GO:0042416	dopamine biosynthetic process	2/319	11/18722	0.0143804317461382	0.0611415021485518	NR4A2/SNCA	2
GO:0043619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	2/319	11/18722	0.0143804317461382	0.0611415021485518	HIF1A/HMOX1	2
GO:0045628	regulation of T-helper 2 cell differentiation	2/319	11/18722	0.0143804317461382	0.0611415021485518	NLRP3/BCL6	2
GO:0045657	positive regulation of monocyte differentiation	2/319	11/18722	0.0143804317461382	0.0611415021485518	JUN/HLA-DRB1	2
GO:0048715	negative regulation of oligodendrocyte differentiation	2/319	11/18722	0.0143804317461382	0.0611415021485518	CTNNB1/HES1	2
GO:0106049	regulation of cellular response to osmotic stress	2/319	11/18722	0.0143804317461382	0.0611415021485518	PTGS2/YBX3	2
GO:1903897	regulation of PERK-mediated unfolded protein response	2/319	11/18722	0.0143804317461382	0.0611415021485518	PPP1R15A/PPP1R15B	2
GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	2/319	11/18722	0.0143804317461382	0.0611415021485518	ATF3/CEBPB	2
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	2/319	11/18722	0.0143804317461382	0.0611415021485518	TNF/HMGB1	2
GO:1902903	regulation of supramolecular fiber organization	13/319	382/18722	0.0143818614881171	0.0611415021485518	TMSB4X/ICAM1/MAPRE1/GRB2/MYADM/BRK1/SNCA/PTGER4/PLEK/RGCC/APOE/COTL1/NCKAP1L	13
GO:0007006	mitochondrial membrane organization	6/319	116/18722	0.0145223926921157	0.0615610620313202	BNIP3L/PPIF/TOMM22/VDAC2/PMAIP1/SNCA	6
GO:1990748	cellular detoxification	6/319	116/18722	0.0145223926921157	0.0615610620313202	SOD2/PIM1/PRDX3/PTGS2/HBG1/APOE	6
GO:0001959	regulation of cytokine-mediated signaling pathway	7/319	150/18722	0.0145254755948384	0.0615610620313202	TNFAIP3/CXCR4/HIF1A/RIPK2/HSP90AB1/IL1RN/ISG15	7
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	8/319	186/18722	0.0146296456339803	0.0618113804740934	BIRC3/TNF/LITAF/CTNNB1/RIPK2/HMOX1/TRIM22/HLA-DRB1	8
GO:0071706	tumor necrosis factor superfamily cytokine production	8/319	186/18722	0.0146296456339803	0.0618113804740934	TNFAIP3/CCL3/ZFP36/RIPK2/IL1A/PF4/HMGB1/THBS1	8
GO:1903555	regulation of tumor necrosis factor superfamily cytokine production	8/319	186/18722	0.0146296456339803	0.0618113804740934	TNFAIP3/CCL3/ZFP36/RIPK2/IL1A/PF4/HMGB1/THBS1	8
GO:0008064	regulation of actin polymerization or depolymerization	8/319	187/18722	0.0150653886306097	0.0633884889775317	TMSB4X/ICAM1/GRB2/MYADM/BRK1/PLEK/COTL1/NCKAP1L	8
GO:0042509	regulation of tyrosine phosphorylation of STAT protein	5/319	85/18722	0.0150709786451036	0.0633884889775317	SOCS3/TNF/OSM/HES1/CSH1	5
GO:0045069	regulation of viral genome replication	5/319	85/18722	0.0150709786451036	0.0633884889775317	CXCL8/TNF/DDX5/ISG15/IFIT1	5
GO:0071277	cellular response to calcium ion	5/319	85/18722	0.0150709786451036	0.0633884889775317	FOS/FOSB/JUND/JUNB/PPIF	5
GO:0051225	spindle assembly	6/319	117/18722	0.0150954343733893	0.0633884889775317	CHMP1B/CHMP2B/MAPRE1/CHMP5/HNRNPU/TUBB	6
GO:0072676	lymphocyte migration	6/319	117/18722	0.0150954343733893	0.0633884889775317	CCL3/CCL4/ICAM1/CCL3L3/GPR183/CCL20	6
GO:0046622	positive regulation of organ growth	4/319	56/18722	0.0151690270117548	0.0635029226530793	PIM1/BASP1/YBX3/SERP1	4
GO:0048008	platelet-derived growth factor receptor signaling pathway	4/319	56/18722	0.0151690270117548	0.0635029226530793	VEGFA/CSRNP1/SNCA/NR4A3	4
GO:0071385	cellular response to glucocorticoid stimulus	4/319	56/18722	0.0151690270117548	0.0635029226530793	DDIT4/ICAM1/ZFP36/HNRNPU	4
GO:0045786	negative regulation of cell cycle	13/319	385/18722	0.0152499432022187	0.0637767207571932	TNFAIP3/KLF4/DUSP1/NR4A1/CDKN1A/TNF/CTNNB1/BCL6/SYF2/BTG1/NPM1/PTGS2/RGCC	13
GO:0001782	B cell homeostasis	3/319	31/18722	0.0154822480178891	0.0641246613801788	TNFAIP3/HIF1A/NCKAP1L	3
GO:0032509	endosome transport via multivesicular body sorting pathway	3/319	31/18722	0.0154822480178891	0.0641246613801788	CHMP1B/CHMP2B/CHMP5	3
GO:0036257	multivesicular body organization	3/319	31/18722	0.0154822480178891	0.0641246613801788	CHMP1B/CHMP2B/CHMP5	3
GO:0045066	regulatory T cell differentiation	3/319	31/18722	0.0154822480178891	0.0641246613801788	BCL6/HLA-DRA/HLA-DRB1	3
GO:0048566	embryonic digestive tract development	3/319	31/18722	0.0154822480178891	0.0641246613801788	CXCL8/TNF/ID2	3
GO:0060795	cell fate commitment involved in formation of primary germ layer	3/319	31/18722	0.0154822480178891	0.0641246613801788	KLF4/CTNNB1/ETS2	3
GO:0070528	protein kinase C signaling	3/319	31/18722	0.0154822480178891	0.0641246613801788	VEGFA/MYADM/PLEK	3
GO:0110150	negative regulation of biomineralization	3/319	31/18722	0.0154822480178891	0.0641246613801788	CCL3/HIF1A/SRGN	3
GO:0030832	regulation of actin filament length	8/319	188/18722	0.0155104814967482	0.0641246613801788	TMSB4X/ICAM1/GRB2/MYADM/BRK1/PLEK/COTL1/NCKAP1L	8
GO:0008643	carbohydrate transport	7/319	152/18722	0.0155203206210844	0.0641246613801788	IL1B/TNF/IRS2/PPBP/SLC2A3/NR4A3/C3	7
GO:0050871	positive regulation of B cell activation	7/319	152/18722	0.0155203206210844	0.0641246613801788	CDKN1A/GPR183/IRS2/BCL6/CD81/STAT6/NCKAP1L	7
GO:0098754	detoxification	7/319	152/18722	0.0155203206210844	0.0641246613801788	SOD2/PIM1/PRDX3/PTGS2/HBG1/APOE/MT2A	7
GO:0015908	fatty acid transport	5/319	86/18722	0.0157849506776465	0.0650871938172567	IL1B/PLIN2/IRS2/APOE/THBS1	5
GO:0022406	membrane docking	5/319	86/18722	0.0157849506776465	0.0650871938172567	ICAM1/STX11/VMP1/SNX3/PLEK	5
GO:0010883	regulation of lipid storage	4/319	57/18722	0.0161007482868042	0.066124052154897	NFKBIA/PLIN2/TNF/C3	4
GO:0033619	membrane protein proteolysis	4/319	57/18722	0.0161007482868042	0.066124052154897	IL1B/TNF/APOE/TIMP3	4
GO:0051785	positive regulation of nuclear division	4/319	57/18722	0.0161007482868042	0.066124052154897	IL1B/EREG/RGCC/IL1A	4
GO:1900024	regulation of substrate adhesion-dependent cell spreading	4/319	57/18722	0.0161007482868042	0.066124052154897	MYADM/LIMS1/GBP1/FBLN1	4
GO:0019646	aerobic electron transport chain	5/319	87/18722	0.0165211340022777	0.0677152361748391	CYCS/COX7A2L/SNCA/NDUFS5/NDUFA6	5
GO:2000177	regulation of neural precursor cell proliferation	5/319	87/18722	0.0165211340022777	0.0677152361748391	HIF1A/VEGFA/CTNNB1/ID2/NAP1L1	5
GO:0001667	ameboidal-type cell migration	15/319	475/18722	0.016678401511023	0.0682917416452345	KLF4/TMSB4X/FN1/NR4A1/HIF1A/VEGFA/TNF/HBEGF/PTGS2/SEMA4D/HMOX1/RGCC/APOE/HMGB1/THBS1	15
GO:0003338	metanephros morphogenesis	3/319	32/18722	0.0168726950633568	0.0683203931205132	CTNNB1/BASP1/HES1	3
GO:0010039	response to iron ion	3/319	32/18722	0.0168726950633568	0.0683203931205132	HIF1A/SNCA/HMOX1	3
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	3/319	32/18722	0.0168726950633568	0.0683203931205132	HSP90AB1/LRG1/THBS1	3
GO:0042744	hydrogen peroxide catabolic process	3/319	32/18722	0.0168726950633568	0.0683203931205132	PRDX3/SNCA/HBG1	3
GO:0050850	positive regulation of calcium-mediated signaling	3/319	32/18722	0.0168726950633568	0.0683203931205132	CCL3/CCL4/TNF	3
GO:0060914	heart formation	3/319	32/18722	0.0168726950633568	0.0683203931205132	PIM1/CTNNB1/HES1	3
GO:0090022	regulation of neutrophil chemotaxis	3/319	32/18722	0.0168726950633568	0.0683203931205132	CXCL8/C5AR1/NCKAP1L	3
GO:1900745	positive regulation of p38MAPK cascade	3/319	32/18722	0.0168726950633568	0.0683203931205132	GADD45B/IL1B/VEGFA	3
GO:1901889	negative regulation of cell junction assembly	3/319	32/18722	0.0168726950633568	0.0683203931205132	IL1B/TNF/THBS1	3
GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus	3/319	32/18722	0.0168726950633568	0.0683203931205132	HSP90AB1/LRG1/THBS1	3
GO:2000191	regulation of fatty acid transport	3/319	32/18722	0.0168726950633568	0.0683203931205132	IL1B/IRS2/THBS1	3
GO:0051897	positive regulation of protein kinase B signaling	6/319	120/18722	0.0169083871273295	0.0683203931205132	CCL3/TNF/HBEGF/OSM/HSP90AB1/THBS1	6
GO:0071901	negative regulation of protein serine/threonine kinase activity	6/319	120/18722	0.0169083871273295	0.0683203931205132	TNFAIP3/DUSP1/IL1B/CDKN1A/DNAJA1/APOE	6
GO:0002903	negative regulation of B cell apoptotic process	2/319	12/18722	0.0170641630508209	0.0683203931205132	IRS2/BCL6	2
GO:0043301	negative regulation of leukocyte degranulation	2/319	12/18722	0.0170641630508209	0.0683203931205132	HMOX1/NCKAP1L	2
GO:0070493	thrombin-activated receptor signaling pathway	2/319	12/18722	0.0170641630508209	0.0683203931205132	SNCA/PLEK	2
GO:0071635	negative regulation of transforming growth factor beta production	2/319	12/18722	0.0170641630508209	0.0683203931205132	FN1/HSP90AB1	2
GO:0071872	cellular response to epinephrine stimulus	2/319	12/18722	0.0170641630508209	0.0683203931205132	PDE4B/SNCA	2
GO:0072376	protein activation cascade	2/319	12/18722	0.0170641630508209	0.0683203931205132	FN1/FBLN1	2
GO:1902950	regulation of dendritic spine maintenance	2/319	12/18722	0.0170641630508209	0.0683203931205132	PRNP/APOE	2
GO:0032481	positive regulation of type I interferon production	4/319	58/18722	0.0170676340877565	0.0683203931205132	HMGB2/RIPK2/ISG15/HMGB1	4
GO:0042743	hydrogen peroxide metabolic process	4/319	58/18722	0.0170676340877565	0.0683203931205132	SOD2/PRDX3/SNCA/HBG1	4
GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	4/319	58/18722	0.0170676340877565	0.0683203931205132	MCL1/PMAIP1/SKIL/S100A8	4
GO:0007260	tyrosine phosphorylation of STAT protein	5/319	88/18722	0.0172797935256382	0.069102364964882	SOCS3/TNF/OSM/HES1/CSH1	5
GO:0002224	toll-like receptor signaling pathway	6/319	121/18722	0.0175446063805164	0.0700251231362163	NFKBIA/TNFAIP3/BIRC3/RIPK2/NMI/HMGB1	6
GO:0042177	negative regulation of protein catabolic process	6/319	121/18722	0.0175446063805164	0.0700251231362163	SNX3/SNCA/HSP90AB1/RPL23/TIMP3/RPL5	6
GO:0001764	neuron migration	7/319	156/18722	0.0176536648913412	0.0703920624328843	NR4A2/DDIT4/PHACTR1/CXCR4/VEGFA/CTNNB1/ZMIZ1	7
GO:0032409	regulation of transporter activity	11/319	310/18722	0.017729462962668	0.0706257967437288	TMSB4X/SGK1/YWHAH/ATP1B3/PPIF/PIM1/PDE4B/PRNP/VMP1/SNCA/IFNGR2	11
GO:0048732	gland development	14/319	436/18722	0.0179041194121637	0.0712525023266263	TNFAIP3/SRSF5/HIF1A/VEGFA/TNF/AREG/CTNNB1/IRS2/ID2/HMOX1/CEBPB/HES1/RPS15/STAT6	14
GO:0046330	positive regulation of JNK cascade	5/319	89/18722	0.0180611868166915	0.0716354653208706	GADD45B/IL1B/TNF/RIPK2/HMGB1	5
GO:0035306	positive regulation of dephosphorylation	4/319	59/18722	0.0180700504835181	0.0716354653208706	PPP1R15A/PPP1R15B/HSP90AB1/PLEK	4
GO:0043407	negative regulation of MAP kinase activity	4/319	59/18722	0.0180700504835181	0.0716354653208706	DUSP1/IL1B/DNAJA1/APOE	4
GO:0090303	positive regulation of wound healing	4/319	59/18722	0.0180700504835181	0.0716354653208706	CXCR4/HBEGF/HMGB1/THBS1	4
GO:0050868	negative regulation of T cell activation	6/319	122/18722	0.018197081730366	0.0720695597240219	BCL6/PRNP/CEBPB/HMGB1/HLA-DRB1/NCKAP1L	6
GO:0036336	dendritic cell migration	3/319	33/18722	0.0183307624227817	0.0723203112476543	CXCR4/GPR183/HMGB1	3
GO:0045920	negative regulation of exocytosis	3/319	33/18722	0.0183307624227817	0.0723203112476543	SNCA/HMOX1/NCKAP1L	3
GO:1902692	regulation of neuroblast proliferation	3/319	33/18722	0.0183307624227817	0.0723203112476543	HIF1A/VEGFA/CTNNB1	3
GO:1904031	positive regulation of cyclin-dependent protein kinase activity	3/319	33/18722	0.0183307624227817	0.0723203112476543	CDKN1A/HSP90AB1/RGCC	3
GO:0016049	cell growth	15/319	482/18722	0.0187612246768397	0.07394764587391	FN1/CXCR4/SGK1/VEGFA/CDKN1A/HBEGF/CTNNB1/BCL6/BTG1/NPM1/SEMA4D/HSP90AB1/SPP1/APOE/S100A8	15
GO:0030901	midbrain development	5/319	90/18722	0.01886556399014	0.0740058124364074	NR4A2/YWHAH/CTNNB1/BASP1/HES1	5
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	5/319	90/18722	0.01886556399014	0.0740058124364074	TRIB1/GABARAP/SUMO2/RNF19B/PIAS1	5
GO:0035304	regulation of protein dephosphorylation	5/319	90/18722	0.01886556399014	0.0740058124364074	PPP1R15A/PPP1R15B/TNF/HSP90AB1/NCKAP1L	5
GO:0070664	negative regulation of leukocyte proliferation	5/319	90/18722	0.01886556399014	0.0740058124364074	TNFAIP3/PRNP/CEBPB/MNDA/HLA-DRB1	5
GO:0030168	platelet activation	6/319	123/18722	0.0188659915916699	0.0740058124364074	FN1/TLN1/PLEK/APOE/PF4/DGKZ	6
GO:0000381	regulation of alternative mRNA splicing, via spliceosome	4/319	60/18722	0.0191083422771898	0.074671478233391	HNRNPA1/YTHDC1/DDX5/HNRNPU	4
GO:0002712	regulation of B cell mediated immunity	4/319	60/18722	0.0191083422771898	0.074671478233391	TNF/BCL6/C3/STAT6	4
GO:0002753	cytoplasmic pattern recognition receptor signaling pathway	4/319	60/18722	0.0191083422771898	0.074671478233391	NFKBIA/TNFAIP3/BIRC3/RIPK2	4
GO:0002889	regulation of immunoglobulin mediated immune response	4/319	60/18722	0.0191083422771898	0.074671478233391	TNF/BCL6/C3/STAT6	4
GO:0060560	developmental growth involved in morphogenesis	9/319	234/18722	0.0192650465640217	0.0752123517803354	FN1/CXCR4/VEGFA/AREG/CTNNB1/SEMA4D/HSP90AB1/SPP1/APOE	9
GO:0035966	response to topologically incorrect protein	7/319	159/18722	0.0193836473981136	0.0755319189134076	ATF3/PPP1R15A/PPP1R15B/DNAJA1/HSP90AB1/SERP1/THBS1	7
GO:0051170	import into nucleus	7/319	159/18722	0.0193836473981136	0.0755319189134076	NFKBIA/HNRNPA1/CDKN1A/PTGS2/HSP90AB1/RPL23/PPP3CA	7
GO:0007015	actin filament organization	14/319	441/18722	0.0195380038635772	0.0756297573225928	TMSB4X/PHACTR1/ICAM1/GRB2/MYADM/BRK1/MARCKSL1/PTGER4/PLEK/TPM3/RGCC/MARCKS/COTL1/NCKAP1L	14
GO:0010508	positive regulation of autophagy	6/319	124/18722	0.0195515111084052	0.0756297573225928	HIF1A/BNIP3L/RIPK2/HMOX1/TRIM22/HMGB1	6
GO:0097237	cellular response to toxic substance	6/319	124/18722	0.0195515111084052	0.0756297573225928	SOD2/PIM1/PRDX3/PTGS2/HBG1/APOE	6
GO:0002275	myeloid cell activation involved in immune response	5/319	91/18722	0.0196931675976437	0.0756297573225928	CCL3/NMI/HMOX1/NR4A3/HMGB1	5
GO:0045930	negative regulation of mitotic cell cycle	9/319	235/18722	0.0197441177905815	0.0756297573225928	KLF4/DUSP1/CDKN1A/TNF/CTNNB1/BCL6/SYF2/BTG1/RGCC	9
GO:0007616	long-term memory	3/319	34/18722	0.0198566545943465	0.0756297573225928	SGK1/PRNP/APOE	3
GO:0035308	negative regulation of protein dephosphorylation	3/319	34/18722	0.0198566545943465	0.0756297573225928	PPP1R15A/TNF/NCKAP1L	3
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	3/319	34/18722	0.0198566545943465	0.0756297573225928	PMAIP1/DDX5/NPM1	3
GO:0051973	positive regulation of telomerase activity	3/319	34/18722	0.0198566545943465	0.0756297573225928	KLF4/CTNNB1/HSP90AB1	3
GO:0002430	complement receptor mediated signaling pathway	2/319	13/18722	0.0199422663433935	0.0756297573225928	C5AR1/FPR3	2
GO:0010917	negative regulation of mitochondrial membrane potential	2/319	13/18722	0.0199422663433935	0.0756297573225928	BNIP3L/PMAIP1	2
GO:0031392	regulation of prostaglandin biosynthetic process	2/319	13/18722	0.0199422663433935	0.0756297573225928	IL1B/PTGS2	2
GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	2/319	13/18722	0.0199422663433935	0.0756297573225928	TNFAIP3/TRIB1	2
GO:0032352	positive regulation of hormone metabolic process	2/319	13/18722	0.0199422663433935	0.0756297573225928	HIF1A/EGR1	2
GO:0032494	response to peptidoglycan	2/319	13/18722	0.0199422663433935	0.0756297573225928	RIPK2/C5AR1	2
GO:0033700	phospholipid efflux	2/319	13/18722	0.0199422663433935	0.0756297573225928	APOE/APOC1	2
GO:0034135	regulation of toll-like receptor 2 signaling pathway	2/319	13/18722	0.0199422663433935	0.0756297573225928	TNFAIP3/HMGB1	2
GO:0035745	T-helper 2 cell cytokine production	2/319	13/18722	0.0199422663433935	0.0756297573225928	NLRP3/CD81	2
GO:0036462	TRAIL-activated apoptotic signaling pathway	2/319	13/18722	0.0199422663433935	0.0756297573225928	ATF3/TIMP3	2
GO:0048711	positive regulation of astrocyte differentiation	2/319	13/18722	0.0199422663433935	0.0756297573225928	ID2/HES1	2
GO:0060100	positive regulation of phagocytosis, engulfment	2/319	13/18722	0.0199422663433935	0.0756297573225928	C3/NCKAP1L	2
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	2/319	13/18722	0.0199422663433935	0.0756297573225928	ZFP36/TOB1	2
GO:0060670	branching involved in labyrinthine layer morphogenesis	2/319	13/18722	0.0199422663433935	0.0756297573225928	SOCS3/GRB2	2
GO:0061469	regulation of type B pancreatic cell proliferation	2/319	13/18722	0.0199422663433935	0.0756297573225928	NR4A1/NR4A3	2
GO:0070424	regulation of nucleotide-binding oligomerization domain containing signaling pathway	2/319	13/18722	0.0199422663433935	0.0756297573225928	TNFAIP3/BIRC3	2
GO:1900272	negative regulation of long-term synaptic potentiation	2/319	13/18722	0.0199422663433935	0.0756297573225928	PRNP/APOE	2
GO:1905155	positive regulation of membrane invagination	2/319	13/18722	0.0199422663433935	0.0756297573225928	C3/NCKAP1L	2
GO:2000551	regulation of T-helper 2 cell cytokine production	2/319	13/18722	0.0199422663433935	0.0756297573225928	NLRP3/CD81	2
GO:2001198	regulation of dendritic cell differentiation	2/319	13/18722	0.0199422663433935	0.0756297573225928	CEBPB/HMGB1	2
GO:0090316	positive regulation of intracellular protein transport	7/319	160/18722	0.0199857690105522	0.0757248814768478	IL1B/ANP32B/PRNP/PTGS2/OAZ1/HSP90AB1/CD81	7
GO:0030865	cortical cytoskeleton organization	4/319	61/18722	0.0201828330543105	0.076260686292528	TNF/TLN1/PLEK/NCKAP1L	4
GO:0043030	regulation of macrophage activation	4/319	61/18722	0.0201828330543105	0.076260686292528	JUND/CCL3/SNCA/THBS1	4
GO:0071384	cellular response to corticosteroid stimulus	4/319	61/18722	0.0201828330543105	0.076260686292528	DDIT4/ICAM1/ZFP36/HNRNPU	4
GO:0110053	regulation of actin filament organization	10/319	277/18722	0.020847755896061	0.0787007571062505	TMSB4X/ICAM1/GRB2/MYADM/BRK1/PTGER4/PLEK/RGCC/COTL1/NCKAP1L	10
GO:0032874	positive regulation of stress-activated MAPK cascade	6/319	126/18722	0.0209730628851751	0.0791011573586743	GADD45B/IL1B/VEGFA/TNF/RIPK2/HMGB1	6
GO:0051100	negative regulation of binding	7/319	162/18722	0.0212289704792849	0.0798673121032899	NFKBIA/JUN/TMSB4X/CDKN1A/HMOX1/IFIT1/PPP3CA	7
GO:0032613	interleukin-10 production	4/319	62/18722	0.0212938252541783	0.0798673121032899	CD83/ISG15/HMGB1/HLA-DRB1	4
GO:0032653	regulation of interleukin-10 production	4/319	62/18722	0.0212938252541783	0.0798673121032899	CD83/ISG15/HMGB1/HLA-DRB1	4
GO:0046824	positive regulation of nucleocytoplasmic transport	4/319	62/18722	0.0212938252541783	0.0798673121032899	IL1B/ANP32B/PTGS2/HSP90AB1	4
GO:0060135	maternal process involved in female pregnancy	4/319	62/18722	0.0212938252541783	0.0798673121032899	JUNB/PRDX3/PTGS2/SPP1	4
GO:0070265	necrotic cell death	4/319	62/18722	0.0212938252541783	0.0798673121032899	BIRC3/PPIF/TNF/YBX3	4
GO:0022898	regulation of transmembrane transporter activity	10/319	278/18722	0.0213121968808827	0.0798673121032899	TMSB4X/YWHAH/ATP1B3/PPIF/PIM1/PDE4B/PRNP/VMP1/SNCA/IFNGR2	10
GO:0032088	negative regulation of NF-kappaB transcription factor activity	5/319	93/18722	0.02141898590726	0.0798759135130299	NFKBIA/TNFAIP3/KLF4/TMSB4X/NLRP3	5
GO:0097306	cellular response to alcohol	5/319	93/18722	0.02141898590726	0.0798759135130299	KLF4/SOD2/CTNNB1/KLF2/PTGER4	5
GO:0033280	response to vitamin D	3/319	35/18722	0.0214505007342216	0.0798759135130299	PIM1/PTGS2/SPP1	3
GO:0034405	response to fluid shear stress	3/319	35/18722	0.0214505007342216	0.0798759135130299	KLF4/PTGS2/KLF2	3
GO:0046640	regulation of alpha-beta T cell proliferation	3/319	35/18722	0.0214505007342216	0.0798759135130299	RIPK2/CD81/HLA-A	3
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	3/319	35/18722	0.0214505007342216	0.0798759135130299	VEGFA/PTGS2/HMOX1	3
GO:2000403	positive regulation of lymphocyte migration	3/319	35/18722	0.0214505007342216	0.0798759135130299	CCL3/CCL4/CCL20	3
GO:0071902	positive regulation of protein serine/threonine kinase activity	8/319	200/18722	0.0216187898056818	0.0804297238834008	IL1B/VEGFA/TNF/SNCA/ERP29/HSP90AB1/RGCC/THBS1	8
GO:0009416	response to light stimulus	11/319	320/18722	0.0218238662550759	0.0811192714056211	FOS/JUND/DUSP1/BHLHE40/HIF1A/CDKN1A/ID2/NPM1/PTGS2/HMGN1/PIAS1	11
GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	5/319	94/18722	0.0223176470253876	0.0828797171828081	TNFAIP3/CDKN1A/CCNL1/RGCC/HERC5	5
GO:0016239	positive regulation of macroautophagy	4/319	63/18722	0.0224416002629957	0.0830399808111391	HIF1A/BNIP3L/RIPK2/HMOX1	4
GO:0046902	regulation of mitochondrial membrane permeability	4/319	63/18722	0.0224416002629957	0.0830399808111391	BNIP3L/PPIF/VDAC2/PMAIP1	4
GO:0050854	regulation of antigen receptor-mediated signaling pathway	4/319	63/18722	0.0224416002629957	0.0830399808111391	PRNP/CD81/GBP1/DGKZ	4
GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	4/319	63/18722	0.0224416002629957	0.0830399808111391	PPP1R15A/PMAIP1/ERP29/CEBPB	4
GO:0070304	positive regulation of stress-activated protein kinase signaling cascade	6/319	128/18722	0.0224630700259785	0.0830446770474799	GADD45B/IL1B/VEGFA/TNF/RIPK2/HMGB1	6
GO:0010959	regulation of metal ion transport	13/319	406/18722	0.0224931358003039	0.0830811152516167	CCL3/CCL4/CXCR4/ICAM1/YWHAH/ATP1B3/SARAF/PDE4B/CTNNB1/PRNP/VMP1/SNCA/PTGS2	13
GO:0000054	ribosomal subunit export from nucleus	2/319	14/18722	0.0230073819955792	0.0837762155746909	NPM1/RPS15	2
GO:0002467	germinal center formation	2/319	14/18722	0.0230073819955792	0.0837762155746909	TNFAIP3/BCL6	2
GO:0002829	negative regulation of type 2 immune response	2/319	14/18722	0.0230073819955792	0.0837762155746909	BCL6/STAT6	2
GO:0006596	polyamine biosynthetic process	2/319	14/18722	0.0230073819955792	0.0837762155746909	SAT1/OAZ1	2
GO:0010771	negative regulation of cell morphogenesis involved in differentiation	2/319	14/18722	0.0230073819955792	0.0837762155746909	GBP1/FBLN1	2
GO:0010872	regulation of cholesterol esterification	2/319	14/18722	0.0230073819955792	0.0837762155746909	APOE/APOC1	2
GO:0031115	negative regulation of microtubule polymerization	2/319	14/18722	0.0230073819955792	0.0837762155746909	MAPRE1/SNCA	2
GO:0033750	ribosome localization	2/319	14/18722	0.0230073819955792	0.0837762155746909	NPM1/RPS15	2
GO:0034616	response to laminar fluid shear stress	2/319	14/18722	0.0230073819955792	0.0837762155746909	KLF4/KLF2	2
GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	2/319	14/18722	0.0230073819955792	0.0837762155746909	PMAIP1/DDX5	2
GO:0045837	negative regulation of membrane potential	2/319	14/18722	0.0230073819955792	0.0837762155746909	BNIP3L/PMAIP1	2
GO:0047484	regulation of response to osmotic stress	2/319	14/18722	0.0230073819955792	0.0837762155746909	PTGS2/YBX3	2
GO:0050930	induction of positive chemotaxis	2/319	14/18722	0.0230073819955792	0.0837762155746909	CXCL8/VEGFA	2
GO:0060576	intestinal epithelial cell development	2/319	14/18722	0.0230073819955792	0.0837762155746909	HIF1A/CDKN1A	2
GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	2/319	14/18722	0.0230073819955792	0.0837762155746909	GBP1/FBLN1	2
GO:1902916	positive regulation of protein polyubiquitination	2/319	14/18722	0.0230073819955792	0.0837762155746909	GABARAP/NMI	2
GO:0030224	monocyte differentiation	3/319	36/18722	0.0231123579648156	0.0839354272026121	JUN/VEGFA/HLA-DRB1	3
GO:0051385	response to mineralocorticoid	3/319	36/18722	0.0231123579648156	0.0839354272026121	FOS/FOSB/CDKN1A	3
GO:0060251	regulation of glial cell proliferation	3/319	36/18722	0.0231123579648156	0.0839354272026121	IL1B/TNF/HES1	3
GO:0007044	cell-substrate junction assembly	5/319	95/18722	0.0232404272447914	0.0839555328676075	FN1/VEGFA/LIMS1/TLN1/THBS1	5
GO:0008585	female gonad development	5/319	95/18722	0.0232404272447914	0.0839555328676075	ICAM1/VEGFA/CEBPB/EREG/RETN	5
GO:0032479	regulation of type I interferon production	5/319	95/18722	0.0232404272447914	0.0839555328676075	HMGB2/RIPK2/NMI/ISG15/HMGB1	5
GO:0032606	type I interferon production	5/319	95/18722	0.0232404272447914	0.0839555328676075	HMGB2/RIPK2/NMI/ISG15/HMGB1	5
GO:0042773	ATP synthesis coupled electron transport	5/319	95/18722	0.0232404272447914	0.0839555328676075	CYCS/COX7A2L/SNCA/NDUFS5/NDUFA6	5
GO:0042775	mitochondrial ATP synthesis coupled electron transport	5/319	95/18722	0.0232404272447914	0.0839555328676075	CYCS/COX7A2L/SNCA/NDUFS5/NDUFA6	5
GO:0043112	receptor metabolic process	7/319	166/18722	0.0238746619351721	0.0861709703384482	CXCL8/VEGFA/CHMP5/GRB2/SNCA/CD81/APOE	7
GO:0051028	mRNA transport	6/319	130/18722	0.0240228086537568	0.0866296196277143	HNRNPA1/SRSF3/ZFP36/SRSF7/YTHDC1/MX2	6
GO:0019079	viral genome replication	6/319	131/18722	0.024829210019975	0.0891381016062693	CXCL8/TNF/DDX5/DEK/ISG15/IFIT1	6
GO:0032570	response to progesterone	3/319	37/18722	0.0248422145792932	0.0891381016062693	FOS/FOSB/THBS1	3
GO:0071985	multivesicular body sorting pathway	3/319	37/18722	0.0248422145792932	0.0891381016062693	CHMP1B/CHMP2B/CHMP5	3
GO:0015909	long-chain fatty acid transport	4/319	65/18722	0.0248485196888311	0.0891381016062693	PLIN2/IRS2/APOE/THBS1	4
GO:0051310	metaphase plate congression	4/319	65/18722	0.0248485196888311	0.0891381016062693	CHMP1B/CHMP2B/CHMP5/HNRNPU	4
GO:0090307	mitotic spindle assembly	4/319	65/18722	0.0248485196888311	0.0891381016062693	CHMP1B/CHMP2B/CHMP5/HNRNPU	4
GO:0070167	regulation of biomineral tissue development	5/319	97/18722	0.0251591504076471	0.090173729141968	CCL3/HIF1A/SRGN/CEBPB/ISG15	5
GO:0017038	protein import	8/319	206/18722	0.0252382359124351	0.0903783866167427	NFKBIA/CDKN1A/TOMM22/PTGS2/HSP90AB1/RPL23/APOE/PPP3CA	8
GO:0001558	regulation of cell growth	13/319	414/18722	0.0258382694983626	0.0920062946432123	FN1/CXCR4/SGK1/VEGFA/CDKN1A/HBEGF/BCL6/BTG1/NPM1/SEMA4D/SPP1/APOE/S100A8	13
GO:0021543	pallium development	7/319	169/18722	0.026002046853411	0.0920062946432123	BCL2A1/PHACTR1/HIF1A/KDM6B/CTNNB1/TMEM14B/ZMIZ1	7
GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus	4/319	66/18722	0.0261081227327609	0.0920062946432123	BCL6/HMGB2/HMGB1/STAT6	4
GO:0016444	somatic cell DNA recombination	4/319	66/18722	0.0261081227327609	0.0920062946432123	BCL6/HMGB2/HMGB1/STAT6	4
GO:0032715	negative regulation of interleukin-6 production	4/319	66/18722	0.0261081227327609	0.0920062946432123	TNFAIP3/TNF/KLF2/NCKAP1L	4
GO:0050766	positive regulation of phagocytosis	4/319	66/18722	0.0261081227327609	0.0920062946432123	IL1B/TNF/C3/NCKAP1L	4
GO:0072678	T cell migration	4/319	66/18722	0.0261081227327609	0.0920062946432123	CCL3/ICAM1/GPR183/CCL20	4
GO:0002070	epithelial cell maturation	2/319	15/18722	0.0262523433754532	0.0920062946432123	HIF1A/CDKN1A	2
GO:0006089	lactate metabolic process	2/319	15/18722	0.0262523433754532	0.0920062946432123	HIF1A/LDHA	2
GO:0006878	cellular copper ion homeostasis	2/319	15/18722	0.0262523433754532	0.0920062946432123	PRNP/MT2A	2
GO:0042994	cytoplasmic sequestering of transcription factor	2/319	15/18722	0.0262523433754532	0.0920062946432123	NFKBIA/TMSB4X	2
GO:0045064	T-helper 2 cell differentiation	2/319	15/18722	0.0262523433754532	0.0920062946432123	NLRP3/BCL6	2
GO:0045475	locomotor rhythm	2/319	15/18722	0.0262523433754532	0.0920062946432123	ID2/EGR1	2
GO:0046321	positive regulation of fatty acid oxidation	2/319	15/18722	0.0262523433754532	0.0920062946432123	IRS2/NR4A3	2
GO:0060099	regulation of phagocytosis, engulfment	2/319	15/18722	0.0262523433754532	0.0920062946432123	C3/NCKAP1L	2
GO:0060211	regulation of nuclear-transcribed mRNA poly(A) tail shortening	2/319	15/18722	0.0262523433754532	0.0920062946432123	ZFP36/TOB1	2
GO:0071428	rRNA-containing ribonucleoprotein complex export from nucleus	2/319	15/18722	0.0262523433754532	0.0920062946432123	NPM1/RPS15	2
GO:0071871	response to epinephrine	2/319	15/18722	0.0262523433754532	0.0920062946432123	PDE4B/SNCA	2
GO:0098760	response to interleukin-7	2/319	15/18722	0.0262523433754532	0.0920062946432123	YBX1/HMGB1	2
GO:0098761	cellular response to interleukin-7	2/319	15/18722	0.0262523433754532	0.0920062946432123	YBX1/HMGB1	2
GO:1900102	negative regulation of endoplasmic reticulum unfolded protein response	2/319	15/18722	0.0262523433754532	0.0920062946432123	PPP1R15A/PPP1R15B	2
GO:1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	2/319	15/18722	0.0262523433754532	0.0920062946432123	ZFP36/TOB1	2
GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA	2/319	15/18722	0.0262523433754532	0.0920062946432123	TNF/PPP3CA	2
GO:2001028	positive regulation of endothelial cell chemotaxis	2/319	15/18722	0.0262523433754532	0.0920062946432123	TMSB4X/VEGFA	2
GO:2001279	regulation of unsaturated fatty acid biosynthetic process	2/319	15/18722	0.0262523433754532	0.0920062946432123	IL1B/PTGS2	2
GO:0046328	regulation of JNK cascade	6/319	133/18722	0.0264958093305764	0.0926539863110577	GADD45B/IL1B/TNF/DNAJA1/RIPK2/HMGB1	6
GO:0002385	mucosal immune response	3/319	38/18722	0.0266399931451399	0.0926539863110577	RPL39/FFAR2/DEFB1	3
GO:0009595	detection of biotic stimulus	3/319	38/18722	0.0266399931451399	0.0926539863110577	NLRP3/HLA-A/HLA-DRB1	3
GO:0030279	negative regulation of ossification	3/319	38/18722	0.0266399931451399	0.0926539863110577	CCL3/HIF1A/SRGN	3
GO:0035886	vascular associated smooth muscle cell differentiation	3/319	38/18722	0.0266399931451399	0.0926539863110577	SOD2/VEGFA/HES1	3
GO:0046633	alpha-beta T cell proliferation	3/319	38/18722	0.0266399931451399	0.0926539863110577	RIPK2/CD81/HLA-A	3
GO:0046676	negative regulation of insulin secretion	3/319	38/18722	0.0266399931451399	0.0926539863110577	PIM3/MIDN/PPP3CA	3
GO:0048246	macrophage chemotaxis	3/319	38/18722	0.0266399931451399	0.0926539863110577	CCL3/C5AR1/THBS1	3
GO:0048713	regulation of oligodendrocyte differentiation	3/319	38/18722	0.0266399931451399	0.0926539863110577	CXCR4/CTNNB1/HES1	3
GO:0110149	regulation of biomineralization	5/319	99/18722	0.0271766853130492	0.0944356607555329	CCL3/HIF1A/SRGN/CEBPB/ISG15	5
GO:1902905	positive regulation of supramolecular fiber organization	8/319	209/18722	0.0271982053842255	0.0944356607555329	ICAM1/MAPRE1/GRB2/BRK1/PLEK/RGCC/APOE/NCKAP1L	8
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	6/319	134/18722	0.0273562886819044	0.0949043905243114	TRIB1/GABARAP/HSP90AB1/SUMO2/RNF19B/PIAS1	6
GO:0032890	regulation of organic acid transport	4/319	67/18722	0.0274054261598002	0.0949946938810613	IL1B/IRS2/SNCA/THBS1	4
GO:0071375	cellular response to peptide hormone stimulus	10/319	290/18722	0.0274880384414304	0.0950479539970675	SOCS3/NR4A2/IL1B/SRSF5/NR4A1/GRB2/IRS2/NR4A3/STAT6/CSH1	10
GO:0030833	regulation of actin filament polymerization	7/319	171/18722	0.0274901525912219	0.0950479539970675	TMSB4X/ICAM1/GRB2/MYADM/BRK1/COTL1/NCKAP1L	7
GO:0046890	regulation of lipid biosynthetic process	7/319	171/18722	0.0274901525912219	0.0950479539970675	IL1B/TNF/PTGS2/EGR1/APOE/C3/APOC1	7
GO:0007623	circadian rhythm	8/319	210/18722	0.0278743756124963	0.096295427010901	JUND/JUN/BHLHE40/NFIL3/KLF10/ID2/HNRNPU/EGR1	8
GO:0022613	ribonucleoprotein complex biogenesis	14/319	463/18722	0.0280976690649401	0.0969853211804942	SRSF5/SBDS/RNU11/LSM6/YTHDC1/NPM1/FRG1/HSP90AB1/RPL3/RPS15/RPL7/RPS28/RPL5/RPS6	14
GO:0046545	development of primary female sexual characteristics	5/319	100/18722	0.0282229495919636	0.0973360283326865	ICAM1/VEGFA/CEBPB/EREG/RETN	5
GO:1990138	neuron projection extension	7/319	172/18722	0.0282554843001617	0.0973665515154776	FN1/CXCR4/VEGFA/CTNNB1/SEMA4D/HSP90AB1/APOE	7
GO:0002701	negative regulation of production of molecular mediator of immune response	3/319	39/18722	0.0285055535094801	0.0980638748765461	TNF/BCL6/HMOX1	3
GO:0032506	cytokinetic process	3/319	39/18722	0.0285055535094801	0.0980638748765461	CHMP1B/CHMP2B/CHMP5	3
GO:0030100	regulation of endocytosis	8/319	211/18722	0.0285621107437488	0.0980942667231003	VEGFA/RAB5C/SNCA/APOE/C3/APOC1/PPP3CA/NCKAP1L	8
GO:0043491	protein kinase B signaling	8/319	211/18722	0.0285621107437488	0.0980942667231003	KLF4/CCL3/IL1B/TNF/HBEGF/OSM/HSP90AB1/THBS1	8
GO:0010812	negative regulation of cell-substrate adhesion	4/319	68/18722	0.0287406081695475	0.0982149959975143	BCL6/GBP1/FBLN1/THBS1	4
GO:0031640	killing of cells of other organism	4/319	68/18722	0.0287406081695475	0.0982149959975143	TREM1/SERPINB9/HMGN2/PF4	4
GO:0032922	circadian regulation of gene expression	4/319	68/18722	0.0287406081695475	0.0982149959975143	BHLHE40/ID2/HNRNPU/EGR1	4
GO:0034394	protein localization to cell surface	4/319	68/18722	0.0287406081695475	0.0982149959975143	TNF/CTNNB1/HSP90AB1/FCN1	4
GO:0042267	natural killer cell mediated cytotoxicity	4/319	68/18722	0.0287406081695475	0.0982149959975143	SERPINB9/RNF19B/HLA-A/TUBB	4
GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein	4/319	68/18722	0.0287406081695475	0.0982149959975143	TNF/OSM/HES1/CSH1	4
GO:0006576	cellular biogenic amine metabolic process	5/319	101/18722	0.0292944312634164	0.0998585463713971	NR4A2/SAT1/SNCA/OAZ1/AOC1	5
GO:0098869	cellular oxidant detoxification	5/319	101/18722	0.0292944312634164	0.0998585463713971	SOD2/PRDX3/PTGS2/HBG1/APOE	5
GO:0150115	cell-substrate junction organization	5/319	101/18722	0.0292944312634164	0.0998585463713971	FN1/VEGFA/LIMS1/TLN1/THBS1	5
GO:0002827	positive regulation of T-helper 1 type immune response	2/319	16/18722	0.0296701724411133	0.0998968705204067	IL1B/RIPK2	2
GO:0002830	positive regulation of type 2 immune response	2/319	16/18722	0.0296701724411133	0.0998968705204067	NLRP3/CD81	2
GO:0009048	dosage compensation by inactivation of X chromosome	2/319	16/18722	0.0296701724411133	0.0998968705204067	YTHDC1/HNRNPU	2
GO:0010919	regulation of inositol phosphate biosynthetic process	2/319	16/18722	0.0296701724411133	0.0998968705204067	SNCA/PLEK	2
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	2/319	16/18722	0.0296701724411133	0.0998968705204067	IL1B/HIF1A	2
GO:0034116	positive regulation of heterotypic cell-cell adhesion	2/319	16/18722	0.0296701724411133	0.0998968705204067	IL1B/TNF	2
GO:0034375	high-density lipoprotein particle remodeling	2/319	16/18722	0.0296701724411133	0.0998968705204067	APOE/APOC1	2
GO:0035067	negative regulation of histone acetylation	2/319	16/18722	0.0296701724411133	0.0998968705204067	SNCA/SET	2
GO:0043923	positive regulation by host of viral transcription	2/319	16/18722	0.0296701724411133	0.0998968705204067	JUN/CHD1	2
GO:0051238	sequestering of metal ion	2/319	16/18722	0.0296701724411133	0.0998968705204067	FTH1/S100A8	2
GO:0061684	chaperone-mediated autophagy	2/319	16/18722	0.0296701724411133	0.0998968705204067	SNCA/EEF1A1	2
GO:0071639	positive regulation of monocyte chemotactic protein-1 production	2/319	16/18722	0.0296701724411133	0.0998968705204067	IL1B/HMGB1	2
GO:1902931	negative regulation of alcohol biosynthetic process	2/319	16/18722	0.0296701724411133	0.0998968705204067	PLEK/APOE	2
GO:1904948	midbrain dopaminergic neuron differentiation	2/319	16/18722	0.0296701724411133	0.0998968705204067	NR4A2/CTNNB1	2
GO:1905153	regulation of membrane invagination	2/319	16/18722	0.0296701724411133	0.0998968705204067	C3/NCKAP1L	2
GO:0050878	regulation of body fluid levels	12/319	379/18722	0.0298248680371214	0.100268143446745	FN1/HIF1A/PLAUR/VEGFA/TLN1/ANXA5/PLEK/APOE/PF4/FBLN1/THBS1/DGKZ	12
GO:0007584	response to nutrient	7/319	174/18722	0.0298292238957355	0.100268143446745	SOD2/PIM1/LDHA/PTGS2/HMOX1/SPP1/DAD1	7
GO:0051651	maintenance of location in cell	8/319	213/18722	0.0299726058056225	0.1006677961331	CCL3/TMSB4X/SRGN/SNCA/FTH1/HNRNPU/APOE/S100A8	8
GO:0050714	positive regulation of protein secretion	6/319	137/18722	0.0300480509903462	0.10083880622148	HIF1A/IRS2/HCAR2/SERP1/IL1A/HLA-DRB1	6
GO:0007004	telomere maintenance via telomerase	4/319	69/18722	0.0301138268610382	0.100977114376613	HNRNPA1/CTNNB1/HSP90AB1/HNRNPU	4
GO:0045833	negative regulation of lipid metabolic process	5/319	102/18722	0.0303912846170394	0.101487005724939	IL1B/TNF/HCAR2/APOE/APOC1	5
GO:0002714	positive regulation of B cell mediated immunity	3/319	40/18722	0.0304386957087935	0.101487005724939	TNF/C3/STAT6	3
GO:0002891	positive regulation of immunoglobulin mediated immune response	3/319	40/18722	0.0304386957087935	0.101487005724939	TNF/C3/STAT6	3
GO:0072210	metanephric nephron development	3/319	40/18722	0.0304386957087935	0.101487005724939	CTNNB1/EGR1/HES1	3
GO:1902686	mitochondrial outer membrane permeabilization involved in programmed cell death	3/319	40/18722	0.0304386957087935	0.101487005724939	BNIP3L/PPIF/VDAC2	3
GO:1904994	regulation of leukocyte adhesion to vascular endothelial cell	3/319	40/18722	0.0304386957087935	0.101487005724939	KLF4/ICAM1/TNF	3
GO:2000142	regulation of DNA-templated transcription, initiation	3/319	40/18722	0.0304386957087935	0.101487005724939	JUN/HMGB1/MED13	3
GO:0000082	G1/S transition of mitotic cell cycle	8/319	214/18722	0.0306955274025397	0.102260383429368	KLF4/CDKN1A/ID2/TMEM14B/RGCC/RPS6/PIAS1/PPP3CA	8
GO:1903322	positive regulation of protein modification by small protein conjugation or removal	6/319	138/18722	0.030982502332347	0.10313284784476	BIRC3/GABARAP/NPM1/RIPK2/NMI/PIAS1	6
GO:0051258	protein polymerization	10/319	296/18722	0.0310136270298708	0.10315292938495	TMSB4X/ICAM1/MAPRE1/GRB2/MYADM/BRK1/VDAC2/SNCA/COTL1/NCKAP1L	10
GO:0007611	learning or memory	9/319	255/18722	0.0312253576596444	0.103689374263973	FOS/JUN/HIF1A/SGK1/PRNP/PTGS2/CEBPB/APOE/PIAS1	9
GO:0043547	positive regulation of GTPase activity	9/319	255/18722	0.0312253576596444	0.103689374263973	CCL3/CCL4/ICAM1/CCL3L3/RGS1/LIMS1/RGS10/SEMA4D/CCL20	9
GO:0048568	embryonic organ development	13/319	427/18722	0.0320362935134803	0.106296370164582	CXCL8/SOCS3/JUNB/HIF1A/DNAJB6/VEGFA/TNF/GRB2/CTNNB1/ID2/SYF2/CEBPB/HES1	13
GO:0031647	regulation of protein stability	10/319	298/18722	0.0322567154727505	0.106941417184256	ATP1B3/PIM1/PRNP/NPM1/SNCA/HSP90AB1/CD81/RPL23/RPL5/DAD1	10
GO:0051302	regulation of cell division	7/319	177/18722	0.0322990119675995	0.10699535713038	IL1B/VEGFA/OSM/PPBP/EREG/IL1A/YBX1	7
GO:0002251	organ or tissue specific immune response	3/319	41/18722	0.0324391627856077	0.107028409479641	RPL39/FFAR2/DEFB1	3
GO:0010907	positive regulation of glucose metabolic process	3/319	41/18722	0.0324391627856077	0.107028409479641	IRS2/PMAIP1/HMGB1	3
GO:0032733	positive regulation of interleukin-10 production	3/319	41/18722	0.0324391627856077	0.107028409479641	CD83/ISG15/HMGB1	3
GO:1902622	regulation of neutrophil migration	3/319	41/18722	0.0324391627856077	0.107028409479641	CXCL8/C5AR1/NCKAP1L	3
GO:2000008	regulation of protein localization to cell surface	3/319	41/18722	0.0324391627856077	0.107028409479641	TNF/CTNNB1/HSP90AB1	3
GO:0042692	muscle cell differentiation	12/319	384/18722	0.032499618285395	0.107141885141346	KDM6B/SOD2/VEGFA/CTNNB1/ID2/HNRNPU/CD81/EREG/HES1/YBX1/PIAS1/PPP3CA	12
GO:0042254	ribosome biogenesis	10/319	299/18722	0.0328912333021176	0.107725857919918	SBDS/LSM6/NPM1/FRG1/RPL3/RPS15/RPL7/RPS28/RPL5/RPS6	10
GO:0007292	female gamete generation	6/319	140/18722	0.0329079183058691	0.107725857919918	CTNNB1/YTHDC1/PTGS2/ZMIZ1/EREG/RPS6	6
GO:0008154	actin polymerization or depolymerization	8/319	217/18722	0.0329359292946154	0.107725857919918	TMSB4X/ICAM1/GRB2/MYADM/BRK1/PLEK/COTL1/NCKAP1L	8
GO:0002228	natural killer cell mediated immunity	4/319	71/18722	0.0329749074827208	0.107725857919918	SERPINB9/RNF19B/HLA-A/TUBB	4
GO:0033555	multicellular organismal response to stress	4/319	71/18722	0.0329749074827208	0.107725857919918	NR4A2/APOE/THBS1/PPP3CA	4
GO:0043550	regulation of lipid kinase activity	4/319	71/18722	0.0329749074827208	0.107725857919918	KLF4/SOCS3/CD81/DGKZ	4
GO:0050795	regulation of behavior	4/319	71/18722	0.0329749074827208	0.107725857919918	CCL3/APOE/NR4A3/RETN	4
GO:0061515	myeloid cell development	4/319	71/18722	0.0329749074827208	0.107725857919918	BCL6/KLF2/RPS6/NCKAP1L	4
GO:0010224	response to UV-B	2/319	17/18722	0.0332540754277299	0.107725857919918	CDKN1A/HMGN1	2
GO:0016045	detection of bacterium	2/319	17/18722	0.0332540754277299	0.107725857919918	HLA-A/HLA-DRB1	2
GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I	2/319	17/18722	0.0332540754277299	0.107725857919918	HLA-C/HLA-A	2
GO:0033151	V(D)J recombination	2/319	17/18722	0.0332540754277299	0.107725857919918	HMGB2/HMGB1	2
GO:0033623	regulation of integrin activation	2/319	17/18722	0.0332540754277299	0.107725857919918	PTGER4/PLEK	2
GO:0042053	regulation of dopamine metabolic process	2/319	17/18722	0.0332540754277299	0.107725857919918	NR4A2/SNCA	2
GO:0042069	regulation of catecholamine metabolic process	2/319	17/18722	0.0332540754277299	0.107725857919918	NR4A2/SNCA	2
GO:0043117	positive regulation of vascular permeability	2/319	17/18722	0.0332540754277299	0.107725857919918	VEGFA/APOE	2
GO:0044539	long-chain fatty acid import into cell	2/319	17/18722	0.0332540754277299	0.107725857919918	IRS2/THBS1	2
GO:0046827	positive regulation of protein export from nucleus	2/319	17/18722	0.0332540754277299	0.107725857919918	IL1B/ANP32B	2
GO:0070875	positive regulation of glycogen metabolic process	2/319	17/18722	0.0332540754277299	0.107725857919918	IRS2/HMGB1	2
GO:0090036	regulation of protein kinase C signaling	2/319	17/18722	0.0332540754277299	0.107725857919918	VEGFA/MYADM	2
GO:0140354	lipid import into cell	2/319	17/18722	0.0332540754277299	0.107725857919918	IRS2/THBS1	2
GO:1900034	regulation of cellular response to heat	2/319	17/18722	0.0332540754277299	0.107725857919918	IER5/DNAJB6	2
GO:0045165	cell fate commitment	9/319	258/18722	0.0332794550129643	0.107725857919918	KLF4/KDM6B/MCL1/IFRD1/CTNNB1/ID2/ETS2/HES1/STAT6	9
GO:0006119	oxidative phosphorylation	6/319	141/18722	0.0338991075208999	0.109645343051471	CYCS/PPIF/COX7A2L/SNCA/NDUFS5/NDUFA6	6
GO:0030330	DNA damage response, signal transduction by p53 class mediator	4/319	72/18722	0.0344629871041386	0.11073911903892	CDKN1A/PMAIP1/DDX5/NPM1	4
GO:0042273	ribosomal large subunit biogenesis	4/319	72/18722	0.0344629871041386	0.11073911903892	NPM1/RPL3/RPL7/RPL5	4
GO:1903036	positive regulation of response to wounding	4/319	72/18722	0.0344629871041386	0.11073911903892	CXCR4/HBEGF/HMGB1/THBS1	4
GO:0034764	positive regulation of transmembrane transport	8/319	219/18722	0.0344899835974919	0.11073911903892	TMSB4X/ATP1B3/IRS2/VMP1/SNCA/IFNGR2/NR4A3/C3	8
GO:2001020	regulation of response to DNA damage stimulus	8/319	219/18722	0.0344899835974919	0.11073911903892	IER3/MCL1/PMAIP1/DDX5/NPM1/SKIL/DEK/HMGB1	8
GO:0010677	negative regulation of cellular carbohydrate metabolic process	3/319	42/18722	0.0345066435146816	0.11073911903892	DDIT4/MIDN/PLEK	3
GO:0010939	regulation of necrotic cell death	3/319	42/18722	0.0345066435146816	0.11073911903892	BIRC3/PPIF/YBX3	3
GO:0032689	negative regulation of interferon-gamma production	3/319	42/18722	0.0345066435146816	0.11073911903892	PRNP/HMGB1/HLA-DRB1	3
GO:0033574	response to testosterone	3/319	42/18722	0.0345066435146816	0.11073911903892	DUSP1/SPP1/THBS1	3
GO:0045687	positive regulation of glial cell differentiation	3/319	42/18722	0.0345066435146816	0.11073911903892	CXCR4/ID2/HES1	3
GO:0001824	blastocyst development	5/319	106/18722	0.035035209633665	0.112085406073149	KLF4/JUNB/SBDS/SKIL/DAD1	5
GO:0002793	positive regulation of peptide secretion	5/319	106/18722	0.035035209633665	0.112085406073149	HIF1A/IRS2/SERP1/S100A8/HLA-DRB1	5
GO:0006090	pyruvate metabolic process	5/319	106/18722	0.035035209633665	0.112085406073149	DDIT4/HIF1A/LDHA/PGK1/NR4A3	5
GO:0046822	regulation of nucleocytoplasmic transport	5/319	106/18722	0.035035209633665	0.112085406073149	IL1B/ANP32B/PTGS2/HSP90AB1/MX2	5
GO:0022618	ribonucleoprotein complex assembly	8/319	220/18722	0.0352853655953658	0.11279792998643	SRSF5/RNU11/YTHDC1/HSP90AB1/RPL3/RPS15/RPS28/RPL5	8
GO:0034763	negative regulation of transmembrane transport	6/319	143/18722	0.0359389782121468	0.114603405102624	IL1B/PPIF/TNF/IRS2/OAZ1/THBS1	6
GO:0042058	regulation of epidermal growth factor receptor signaling pathway	4/319	73/18722	0.035989539281802	0.114603405102624	PLAUR/HBEGF/AREG/EREG	4
GO:0043299	leukocyte degranulation	4/319	73/18722	0.035989539281802	0.114603405102624	CCL3/HMOX1/NR4A3/NCKAP1L	4
GO:0051298	centrosome duplication	4/319	73/18722	0.035989539281802	0.114603405102624	CHMP1B/CHMP2B/CHMP5/NPM1	4
GO:0072089	stem cell proliferation	4/319	73/18722	0.035989539281802	0.114603405102624	PIM1/HMGB2/HNRNPU/FBLN1	4
GO:0008406	gonad development	8/319	221/18722	0.0360930779612238	0.114755331398756	ICAM1/VEGFA/HMGB2/BASP1/CEBPB/YBX3/EREG/RETN	8
GO:0010810	regulation of cell-substrate adhesion	8/319	221/18722	0.0360930779612238	0.114755331398756	FN1/VEGFA/MYADM/BCL6/LIMS1/GBP1/FBLN1/THBS1	8
GO:0007229	integrin-mediated signaling pathway	5/319	107/18722	0.0362609445488961	0.115110998486882	FN1/LIMS1/TLN1/PLEK/ISG15	5
GO:2000060	positive regulation of ubiquitin-dependent protein catabolic process	5/319	107/18722	0.0362609445488961	0.115110998486882	TRIB1/GABARAP/SUMO2/RNF19B/PIAS1	5
GO:0040013	negative regulation of locomotion	12/319	391/18722	0.0365275092778509	0.1154870692421	KLF4/DUSP1/TRIB1/TNF/SEMA4D/HMOX1/PTGER4/RGCC/APOE/FBLN1/HMGB1/THBS1	12
GO:0014002	astrocyte development	3/319	43/18722	0.036640775041135	0.1154870692421	TNF/C5AR1/S100A8	3
GO:0033173	calcineurin-NFAT signaling cascade	3/319	43/18722	0.036640775041135	0.1154870692421	TNF/PRNP/PPP3CA	3
GO:0035794	positive regulation of mitochondrial membrane permeability	3/319	43/18722	0.036640775041135	0.1154870692421	BNIP3L/PPIF/VDAC2	3
GO:0090278	negative regulation of peptide hormone secretion	3/319	43/18722	0.036640775041135	0.1154870692421	PIM3/MIDN/PPP3CA	3
GO:0140353	lipid export from cell	3/319	43/18722	0.036640775041135	0.1154870692421	IL1B/SPP1/RETN	3
GO:1904706	negative regulation of vascular associated smooth muscle cell proliferation	3/319	43/18722	0.036640775041135	0.1154870692421	SOD2/CDKN1A/HMOX1	3
GO:0043087	regulation of GTPase activity	11/319	348/18722	0.0369393028847233	0.1154870692421	CCL3/CCL4/ICAM1/CCL3L3/BCL6/RGS1/LIMS1/RGS10/SEMA4D/CCL20/CCPG1	11
GO:0007549	dosage compensation	2/319	18/18722	0.0369974386260873	0.1154870692421	YTHDC1/HNRNPU	2
GO:0030728	ovulation	2/319	18/18722	0.0369974386260873	0.1154870692421	PTGS2/EREG	2
GO:0034433	steroid esterification	2/319	18/18722	0.0369974386260873	0.1154870692421	APOE/APOC1	2
GO:0034434	sterol esterification	2/319	18/18722	0.0369974386260873	0.1154870692421	APOE/APOC1	2
GO:0034435	cholesterol esterification	2/319	18/18722	0.0369974386260873	0.1154870692421	APOE/APOC1	2
GO:0035372	protein localization to microtubule	2/319	18/18722	0.0369974386260873	0.1154870692421	MAPRE1/HNRNPU	2
GO:0036499	PERK-mediated unfolded protein response	2/319	18/18722	0.0369974386260873	0.1154870692421	PPP1R15A/PPP1R15B	2
GO:0045116	protein neddylation	2/319	18/18722	0.0369974386260873	0.1154870692421	HIF1A/RPL5	2
GO:0045953	negative regulation of natural killer cell mediated cytotoxicity	2/319	18/18722	0.0369974386260873	0.1154870692421	SERPINB9/HLA-A	2
GO:0055070	copper ion homeostasis	2/319	18/18722	0.0369974386260873	0.1154870692421	PRNP/MT2A	2
GO:0060546	negative regulation of necroptotic process	2/319	18/18722	0.0369974386260873	0.1154870692421	BIRC3/YBX3	2
GO:0060716	labyrinthine layer blood vessel development	2/319	18/18722	0.0369974386260873	0.1154870692421	JUNB/HES1	2
GO:1900151	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	2/319	18/18722	0.0369974386260873	0.1154870692421	ZFP36/TOB1	2
GO:1902001	fatty acid transmembrane transport	2/319	18/18722	0.0369974386260873	0.1154870692421	IRS2/THBS1	2
GO:0007173	epidermal growth factor receptor signaling pathway	5/319	108/18722	0.0375128020347163	0.116694681567388	PLAUR/HBEGF/AREG/GRB2/EREG	5
GO:0034446	substrate adhesion-dependent cell spreading	5/319	108/18722	0.0375128020347163	0.116694681567388	FN1/MYADM/LIMS1/GBP1/FBLN1	5
GO:0003151	outflow tract morphogenesis	4/319	74/18722	0.0375546250823776	0.116694681567388	HIF1A/VEGFA/CTNNB1/HES1	4
GO:0010822	positive regulation of mitochondrion organization	4/319	74/18722	0.0375546250823776	0.116694681567388	HIF1A/PLAUR/PPIF/PMAIP1	4
GO:0030968	endoplasmic reticulum unfolded protein response	4/319	74/18722	0.0375546250823776	0.116694681567388	ATF3/PPP1R15A/PPP1R15B/SERP1	4
GO:0048844	artery morphogenesis	4/319	74/18722	0.0375546250823776	0.116694681567388	VEGFA/ZMIZ1/HES1/APOE	4
GO:0007051	spindle organization	7/319	184/18722	0.0385841794586356	0.119803294376473	CHMP1B/CHMP2B/MAPRE1/CHMP5/SBDS/HNRNPU/TUBB	7
GO:0002792	negative regulation of peptide secretion	3/319	44/18722	0.0388411454329162	0.120057104417082	PIM3/MIDN/PPP3CA	3
GO:0030521	androgen receptor signaling pathway	3/319	44/18722	0.0388411454329162	0.120057104417082	DNAJA1/DDX5/ZMIZ1	3
GO:0032620	interleukin-17 production	3/319	44/18722	0.0388411454329162	0.120057104417082	OSM/PRNP/NCKAP1L	3
GO:0032660	regulation of interleukin-17 production	3/319	44/18722	0.0388411454329162	0.120057104417082	OSM/PRNP/NCKAP1L	3
GO:0046427	positive regulation of receptor signaling pathway via JAK-STAT	3/319	44/18722	0.0388411454329162	0.120057104417082	TNF/HES1/CSH1	3
GO:0051150	regulation of smooth muscle cell differentiation	3/319	44/18722	0.0388411454329162	0.120057104417082	SOD2/EREG/PIAS1	3
GO:0006278	RNA-dependent DNA biosynthetic process	4/319	75/18722	0.0391582869414181	0.120855643855983	HNRNPA1/CTNNB1/HSP90AB1/HNRNPU	4
GO:0033077	T cell differentiation in thymus	4/319	75/18722	0.0391582869414181	0.120855643855983	IL1B/CTNNB1/IL1A/RPS6	4
GO:0006364	rRNA processing	8/319	225/18722	0.0394485764414358	0.12166023837265	SBDS/LSM6/FRG1/RPS15/RPL7/RPS28/RPL5/RPS6	8
GO:0051896	regulation of protein kinase B signaling	7/319	185/18722	0.039542984157705	0.121859975916286	KLF4/CCL3/TNF/HBEGF/OSM/HSP90AB1/THBS1	7
GO:0022604	regulation of cell morphogenesis	10/319	309/18722	0.0397242793887213	0.122326975705643	CCL3/FN1/CXCR4/ICAM1/VEGFA/MYADM/LIMS1/SEMA4D/GBP1/FBLN1	10
GO:0007088	regulation of mitotic nuclear division	5/319	110/18722	0.0400952602624101	0.123284678338645	DUSP1/IL1B/EREG/RGCC/IL1A	5
GO:0061387	regulation of extent of cell growth	5/319	110/18722	0.0400952602624101	0.123284678338645	FN1/VEGFA/SEMA4D/SPP1/APOE	5
GO:0001889	liver development	6/319	147/18722	0.0402513860672368	0.123672233275344	TNFAIP3/SRSF5/HMOX1/CEBPB/HES1/RPS15	6
GO:0001937	negative regulation of endothelial cell proliferation	4/319	76/18722	0.0408005489451324	0.123795663840129	TNF/RGCC/APOE/THBS1	4
GO:0045685	regulation of glial cell differentiation	4/319	76/18722	0.0408005489451324	0.123795663840129	CXCR4/CTNNB1/ID2/HES1	4
GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	4/319	76/18722	0.0408005489451324	0.123795663840129	DDIT4/CDKN1A/PMAIP1/DDX5	4
GO:0000028	ribosomal small subunit assembly	2/319	19/18722	0.0408938242507652	0.123795663840129	RPS15/RPS28	2
GO:0002281	macrophage activation involved in immune response	2/319	19/18722	0.0408938242507652	0.123795663840129	NMI/HMGB1	2
GO:0002716	negative regulation of natural killer cell mediated immunity	2/319	19/18722	0.0408938242507652	0.123795663840129	SERPINB9/HLA-A	2
GO:0002902	regulation of B cell apoptotic process	2/319	19/18722	0.0408938242507652	0.123795663840129	IRS2/BCL6	2
GO:0010759	positive regulation of macrophage chemotaxis	2/319	19/18722	0.0408938242507652	0.123795663840129	C5AR1/THBS1	2
GO:0010829	negative regulation of glucose transmembrane transport	2/319	19/18722	0.0408938242507652	0.123795663840129	IL1B/TNF	2
GO:0031065	positive regulation of histone deacetylation	2/319	19/18722	0.0408938242507652	0.123795663840129	VEGFA/BCL6	2
GO:0032026	response to magnesium ion	2/319	19/18722	0.0408938242507652	0.123795663840129	SNCA/THBS1	2
GO:0045603	positive regulation of endothelial cell differentiation	2/319	19/18722	0.0408938242507652	0.123795663840129	CTNNB1/BTG1	2
GO:0048245	eosinophil chemotaxis	2/319	19/18722	0.0408938242507652	0.123795663840129	CCL3/CCL4	2
GO:0062099	negative regulation of programmed necrotic cell death	2/319	19/18722	0.0408938242507652	0.123795663840129	BIRC3/YBX3	2
GO:0070233	negative regulation of T cell apoptotic process	2/319	19/18722	0.0408938242507652	0.123795663840129	HIF1A/TSC22D3	2
GO:0140131	positive regulation of lymphocyte chemotaxis	2/319	19/18722	0.0408938242507652	0.123795663840129	CCL3/CCL4	2
GO:1900221	regulation of amyloid-beta clearance	2/319	19/18722	0.0408938242507652	0.123795663840129	TNF/APOE	2
GO:1903975	regulation of glial cell migration	2/319	19/18722	0.0408938242507652	0.123795663840129	CCL3/GPR183	2
GO:2000269	regulation of fibroblast apoptotic process	2/319	19/18722	0.0408938242507652	0.123795663840129	BTG1/STK17B	2
GO:2001185	regulation of CD8-positive, alpha-beta T cell activation	2/319	19/18722	0.0408938242507652	0.123795663840129	HLA-A/NCKAP1L	2
GO:0002920	regulation of humoral immune response	3/319	45/18722	0.0411072961499439	0.123985395797813	IL1B/TNF/C3	3
GO:0008631	intrinsic apoptotic signaling pathway in response to oxidative stress	3/319	45/18722	0.0411072961499439	0.123985395797813	HIF1A/SOD2/MCL1	3
GO:0035307	positive regulation of protein dephosphorylation	3/319	45/18722	0.0411072961499439	0.123985395797813	PPP1R15A/PPP1R15B/HSP90AB1	3
GO:0048546	digestive tract morphogenesis	3/319	45/18722	0.0411072961499439	0.123985395797813	HIF1A/CTNNB1/ID2	3
GO:0071364	cellular response to epidermal growth factor stimulus	3/319	45/18722	0.0411072961499439	0.123985395797813	NCL/ZFP36/EEF1A1	3
GO:0045137	development of primary sexual characteristics	8/319	227/18722	0.0412020126001823	0.124088991794395	ICAM1/VEGFA/HMGB2/BASP1/CEBPB/YBX3/EREG/RETN	8
GO:0071826	ribonucleoprotein complex subunit organization	8/319	227/18722	0.0412020126001823	0.124088991794395	SRSF5/RNU11/YTHDC1/HSP90AB1/RPL3/RPS15/RPS28/RPL5	8
GO:0070507	regulation of microtubule cytoskeleton organization	6/319	148/18722	0.041378471710488	0.124529207321974	CHMP1B/CHMP2B/MAPRE1/CHMP5/SNCA/HNRNPU	6
GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	5/319	111/18722	0.0414260280043988	0.124581127378262	KLF4/FN1/TNF/OSM/SEMA4D	5
GO:0061136	regulation of proteasomal protein catabolic process	7/319	187/18722	0.0415070433545705	0.124733519905438	TRIB1/GABARAP/HSP90AB1/SUMO2/RNF19B/APOE/PIAS1	7
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	11/319	355/18722	0.0416469162885753	0.125062434523253	FOS/JUN/DDX5/SKIL/HSP90AB1/ZMIZ1/LRG1/EGR1/TOB1/HES1/THBS1	11
GO:0006091	generation of precursor metabolites and energy	14/319	490/18722	0.0420426836932308	0.126158739169979	DDIT4/HIF1A/CYCS/PPIF/COX7A2L/LDHA/PGK1/IRS2/SNCA/NCF2/NR4A3/HMGB1/NDUFS5/NDUFA6	14
GO:0002200	somatic diversification of immune receptors	4/319	77/18722	0.0424814171206467	0.127289435701879	BCL6/HMGB2/HMGB1/STAT6	4
GO:0007492	endoderm development	4/319	77/18722	0.0424814171206467	0.127289435701879	DUSP2/DUSP1/FN1/CTNNB1	4
GO:0000956	nuclear-transcribed mRNA catabolic process	5/319	112/18722	0.0427832523615364	0.128007241963811	ZFP36/ETF1/DDX5/TOB1/SSB	5
GO:0043406	positive regulation of MAP kinase activity	5/319	112/18722	0.0427832523615364	0.128007241963811	IL1B/VEGFA/TNF/ERP29/THBS1	5
GO:0033157	regulation of intracellular protein transport	8/319	229/18722	0.0430065517864167	0.128581770468334	IL1B/BNIP3L/ANP32B/PRNP/PTGS2/OAZ1/HSP90AB1/CD81	8
GO:0010828	positive regulation of glucose transmembrane transport	3/319	46/18722	0.0434387244321996	0.129685255004192	IRS2/NR4A3/C3	3
GO:0043616	keratinocyte proliferation	3/319	46/18722	0.0434387244321996	0.129685255004192	ZFP36/AREG/EREG	3
GO:0009060	aerobic respiration	7/319	189/18722	0.0435334892818912	0.129873856631244	HIF1A/CYCS/PPIF/COX7A2L/SNCA/NDUFS5/NDUFA6	7
GO:0061008	hepaticobiliary system development	6/319	150/18722	0.0436919684649034	0.130252126438882	TNFAIP3/SRSF5/HMOX1/CEBPB/HES1/RPS15	6
GO:0045333	cellular respiration	8/319	230/18722	0.0439281269455401	0.130861253531243	HIF1A/CYCS/PPIF/COX7A2L/SNCA/NR4A3/NDUFS5/NDUFA6	8
GO:0031623	receptor internalization	5/319	113/18722	0.0441669961700609	0.131198423528313	CXCL8/VEGFA/GRB2/SNCA/CD81	5
GO:0044106	cellular amine metabolic process	5/319	113/18722	0.0441669961700609	0.131198423528313	NR4A2/SAT1/SNCA/OAZ1/AOC1	5
GO:0030500	regulation of bone mineralization	4/319	78/18722	0.0442008797340584	0.131198423528313	CCL3/HIF1A/SRGN/ISG15	4
GO:0032024	positive regulation of insulin secretion	4/319	78/18722	0.0442008797340584	0.131198423528313	HIF1A/IRS2/SERP1/HLA-DRB1	4
GO:0090559	regulation of membrane permeability	4/319	78/18722	0.0442008797340584	0.131198423528313	BNIP3L/PPIF/VDAC2/PMAIP1	4
GO:2000146	negative regulation of cell motility	11/319	359/18722	0.0445159202678469	0.131297703521364	KLF4/DUSP1/TRIB1/TNF/HMOX1/PTGER4/RGCC/APOE/FBLN1/HMGB1/THBS1	11
GO:0030041	actin filament polymerization	7/319	190/18722	0.0445702676363923	0.131297703521364	TMSB4X/ICAM1/GRB2/MYADM/BRK1/COTL1/NCKAP1L	7
GO:0031497	chromatin assembly	6/319	151/18722	0.0448785177232928	0.131297703521364	ANP32B/HMGB2/NPM1/SET/NAP1L1/HMGB1	6
GO:0071333	cellular response to glucose stimulus	6/319	151/18722	0.0448785177232928	0.131297703521364	PIM3/HIF1A/ICAM1/IRS2/HLA-DRB1/PPP3CA	6
GO:0002834	regulation of response to tumor cell	2/319	20/18722	0.0449369663961466	0.131297703521364	HMGB1/HLA-DRB1	2
GO:0002837	regulation of immune response to tumor cell	2/319	20/18722	0.0449369663961466	0.131297703521364	HMGB1/HLA-DRB1	2
GO:0003159	morphogenesis of an endothelium	2/319	20/18722	0.0449369663961466	0.131297703521364	CXCR4/CTNNB1	2
GO:0006883	cellular sodium ion homeostasis	2/319	20/18722	0.0449369663961466	0.131297703521364	ATP1B3/IL1A	2
GO:0009713	catechol-containing compound biosynthetic process	2/319	20/18722	0.0449369663961466	0.131297703521364	NR4A2/SNCA	2
GO:0010042	response to manganese ion	2/319	20/18722	0.0449369663961466	0.131297703521364	SOD2/PTGS2	2
GO:0032211	negative regulation of telomere maintenance via telomerase	2/319	20/18722	0.0449369663961466	0.131297703521364	HNRNPA1/HNRNPU	2
GO:0032986	protein-DNA complex disassembly	2/319	20/18722	0.0449369663961466	0.131297703521364	SET/RPL23	2
GO:0042423	catecholamine biosynthetic process	2/319	20/18722	0.0449369663961466	0.131297703521364	NR4A2/SNCA	2
GO:0048025	negative regulation of mRNA splicing, via spliceosome	2/319	20/18722	0.0449369663961466	0.131297703521364	SRSF7/NPM1	2
GO:0048670	regulation of collateral sprouting	2/319	20/18722	0.0449369663961466	0.131297703521364	SEMA4D/SPP1	2
GO:0060231	mesenchymal to epithelial transition	2/319	20/18722	0.0449369663961466	0.131297703521364	CTNNB1/BASP1	2
GO:0060252	positive regulation of glial cell proliferation	2/319	20/18722	0.0449369663961466	0.131297703521364	IL1B/TNF	2
GO:0061154	endothelial tube morphogenesis	2/319	20/18722	0.0449369663961466	0.131297703521364	CXCR4/CTNNB1	2
GO:0098543	detection of other organism	2/319	20/18722	0.0449369663961466	0.131297703521364	HLA-A/HLA-DRB1	2
GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	2/319	20/18722	0.0449369663961466	0.131297703521364	HIF1A/SOD2	2
GO:2000010	positive regulation of protein localization to cell surface	2/319	20/18722	0.0449369663961466	0.131297703521364	TNF/HSP90AB1	2
GO:2000757	negative regulation of peptidyl-lysine acetylation	2/319	20/18722	0.0449369663961466	0.131297703521364	SNCA/SET	2
GO:0022904	respiratory electron transport chain	5/319	114/18722	0.0455773140572804	0.132885346162751	CYCS/COX7A2L/SNCA/NDUFS5/NDUFA6	5
GO:0046660	female sex differentiation	5/319	114/18722	0.0455773140572804	0.132885346162751	ICAM1/VEGFA/CEBPB/EREG/RETN	5
GO:1901800	positive regulation of proteasomal protein catabolic process	5/319	114/18722	0.0455773140572804	0.132885346162751	TRIB1/GABARAP/SUMO2/RNF19B/PIAS1	5
GO:0032369	negative regulation of lipid transport	3/319	47/18722	0.0458348856089915	0.132928935056601	IRS2/THBS1/APOC1	3
GO:0042311	vasodilation	3/319	47/18722	0.0458348856089915	0.132928935056601	SOD2/KLF2/APOE	3
GO:0046677	response to antibiotic	3/319	47/18722	0.0458348856089915	0.132928935056601	KDM6B/RPL23/AOC1	3
GO:0048483	autonomic nervous system development	3/319	47/18722	0.0458348856089915	0.132928935056601	FN1/CTNNB1/HES1	3
GO:0051972	regulation of telomerase activity	3/319	47/18722	0.0458348856089915	0.132928935056601	KLF4/CTNNB1/HSP90AB1	3
GO:0090279	regulation of calcium ion import	3/319	47/18722	0.0458348856089915	0.132928935056601	CCL3/CTNNB1/PRNP	3
GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	3/319	47/18722	0.0458348856089915	0.132928935056601	VEGFA/HMOX1/THBS1	3
GO:0010506	regulation of autophagy	10/319	317/18722	0.0458509437874629	0.132928935056601	HIF1A/MCL1/BNIP3L/SNCA/RIPK2/HMOX1/EEF1A1/TRIM22/HMGB1/ATP6V1B2	10
GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	4/319	79/18722	0.0459589075956156	0.13296063977873	FN1/TNF/OSM/SEMA4D	4
GO:0050772	positive regulation of axonogenesis	4/319	79/18722	0.0459589075956156	0.13296063977873	FN1/VEGFA/SKIL/SEMA4D	4
GO:1901184	regulation of ERBB signaling pathway	4/319	79/18722	0.0459589075956156	0.13296063977873	PLAUR/HBEGF/AREG/EREG	4
GO:0031056	regulation of histone modification	6/319	152/18722	0.0460850189740685	0.133231725036846	IL1B/VEGFA/CTNNB1/BCL6/SNCA/SET	6
GO:0015980	energy derivation by oxidation of organic compounds	10/319	318/18722	0.0466592800178948	0.134797118871093	HIF1A/CYCS/PPIF/COX7A2L/IRS2/SNCA/NR4A3/HMGB1/NDUFS5/NDUFA6	10
GO:0043270	positive regulation of ion transport	9/319	275/18722	0.0466973904242498	0.134812480361019	CCL3/IL1B/TMSB4X/CCL4/ATP1B3/VMP1/SNCA/IFNGR2/CEBPB	9
GO:0030278	regulation of ossification	5/319	115/18722	0.0470142524800908	0.135536880747302	CCL3/HIF1A/SRGN/PTGER4/ISG15	5
GO:0043279	response to alkaloid	5/319	115/18722	0.0470142524800908	0.135536880747302	FOSB/CXCR4/ICAM1/SNCA/HSP90AB1	5
GO:0071331	cellular response to hexose stimulus	6/319	153/18722	0.0473115302393975	0.136298318720507	PIM3/HIF1A/ICAM1/IRS2/HLA-DRB1/PPP3CA	6
GO:0007548	sex differentiation	9/319	276/18722	0.0475841311450406	0.136987649255786	ICAM1/VEGFA/CTNNB1/HMGB2/BASP1/CEBPB/YBX3/EREG/RETN	9
GO:0048588	developmental cell growth	8/319	234/18722	0.0477443675821474	0.137096838631803	FN1/CXCR4/VEGFA/CTNNB1/SEMA4D/HSP90AB1/SPP1/APOE	8
GO:0001570	vasculogenesis	4/319	80/18722	0.0477554543713795	0.137096838631803	JUNB/VEGFA/CTNNB1/ZMIZ1	4
GO:0051303	establishment of chromosome localization	4/319	80/18722	0.0477554543713795	0.137096838631803	CHMP1B/CHMP2B/CHMP5/HNRNPU	4
GO:0071229	cellular response to acid chemical	4/319	80/18722	0.0477554543713795	0.137096838631803	VEGFA/TNF/KLF2/CEBPB	4
GO:0002686	negative regulation of leukocyte migration	3/319	48/18722	0.0482951953315583	0.137971888817259	DUSP1/HMOX1/PTGER4	3
GO:0045912	negative regulation of carbohydrate metabolic process	3/319	48/18722	0.0482951953315583	0.137971888817259	DDIT4/MIDN/PLEK	3
GO:0090199	regulation of release of cytochrome c from mitochondria	3/319	48/18722	0.0482951953315583	0.137971888817259	PLAUR/PPIF/PMAIP1	3
GO:0097720	calcineurin-mediated signaling	3/319	48/18722	0.0482951953315583	0.137971888817259	TNF/PRNP/PPP3CA	3
GO:1902003	regulation of amyloid-beta formation	3/319	48/18722	0.0482951953315583	0.137971888817259	TNF/PRNP/APOE	3
GO:1905710	positive regulation of membrane permeability	3/319	48/18722	0.0482951953315583	0.137971888817259	BNIP3L/PPIF/VDAC2	3
GO:2000059	negative regulation of ubiquitin-dependent protein catabolic process	3/319	48/18722	0.0482951953315583	0.137971888817259	HSP90AB1/RPL23/RPL5	3
GO:0071326	cellular response to monosaccharide stimulus	6/319	154/18722	0.0485581051098794	0.13862664590744	PIM3/HIF1A/ICAM1/IRS2/HLA-DRB1/PPP3CA	6
GO:0006123	mitochondrial electron transport, cytochrome c to oxygen	2/319	21/18722	0.0491207670784736	0.138882719023112	CYCS/COX7A2L	2
GO:0030449	regulation of complement activation	2/319	21/18722	0.0491207670784736	0.138882719023112	IL1B/C3	2
GO:0035455	response to interferon-alpha	2/319	21/18722	0.0491207670784736	0.138882719023112	MX2/IFIT3	2
GO:0039702	viral budding via host ESCRT complex	2/319	21/18722	0.0491207670784736	0.138882719023112	CHMP1B/CHMP2B	2
GO:0044342	type B pancreatic cell proliferation	2/319	21/18722	0.0491207670784736	0.138882719023112	NR4A1/NR4A3	2
GO:0045655	regulation of monocyte differentiation	2/319	21/18722	0.0491207670784736	0.138882719023112	JUN/HLA-DRB1	2
GO:0046597	negative regulation of viral entry into host cell	2/319	21/18722	0.0491207670784736	0.138882719023112	SNX3/FCN1	2
GO:0046885	regulation of hormone biosynthetic process	2/319	21/18722	0.0491207670784736	0.138882719023112	HIF1A/EGR1	2
GO:0050849	negative regulation of calcium-mediated signaling	2/319	21/18722	0.0491207670784736	0.138882719023112	PRNP/PLEK	2
GO:0051152	positive regulation of smooth muscle cell differentiation	2/319	21/18722	0.0491207670784736	0.138882719023112	SOD2/PIAS1	2
GO:0071605	monocyte chemotactic protein-1 production	2/319	21/18722	0.0491207670784736	0.138882719023112	IL1B/HMGB1	2
GO:0071637	regulation of monocyte chemotactic protein-1 production	2/319	21/18722	0.0491207670784736	0.138882719023112	IL1B/HMGB1	2
GO:0097062	dendritic spine maintenance	2/319	21/18722	0.0491207670784736	0.138882719023112	PRNP/APOE	2
GO:2000047	regulation of cell-cell adhesion mediated by cadherin	2/319	21/18722	0.0491207670784736	0.138882719023112	VEGFA/RGCC	2
GO:0006096	glycolytic process	4/319	81/18722	0.0495904569007567	0.139730204468136	DDIT4/HIF1A/LDHA/PGK1	4
GO:0010833	telomere maintenance via telomere lengthening	4/319	81/18722	0.0495904569007567	0.139730204468136	HNRNPA1/CTNNB1/HSP90AB1/HNRNPU	4
GO:0014032	neural crest cell development	4/319	81/18722	0.0495904569007567	0.139730204468136	FN1/HIF1A/SEMA4D/HES1	4
GO:0060968	regulation of gene silencing	4/319	81/18722	0.0495904569007567	0.139730204468136	TNF/ZFP36/DDX5/PPP3CA	4
GO:2000243	positive regulation of reproductive process	4/319	81/18722	0.0495904569007567	0.139730204468136	VEGFA/CTNNB1/DEFB1/RETN	4
GO:0016072	rRNA metabolic process	8/319	236/18722	0.0497311396273813	0.139934780977525	SBDS/LSM6/FRG1/RPS15/RPL7/RPS28/RPL5/RPS6	8
GO:0048762	mesenchymal cell differentiation	8/319	236/18722	0.0497311396273813	0.139934780977525	IL1B/FN1/HIF1A/CTNNB1/DDX5/SEMA4D/RGCC/HES1	8
GO:0006606	protein import into nucleus	6/319	155/18722	0.0498247927416784	0.140102409686074	NFKBIA/CDKN1A/PTGS2/HSP90AB1/RPL23/PPP3CA	6
GO:0051271	negative regulation of cellular component movement	11/319	367/18722	0.0506553057183368	0.141927336580598	KLF4/DUSP1/TRIB1/TNF/HMOX1/PTGER4/RGCC/APOE/FBLN1/HMGB1/THBS1	11
GO:0002762	negative regulation of myeloid leukocyte differentiation	3/319	49/18722	0.0508190317311213	0.141927336580598	CCL3/TRIB1/CTNNB1	3
GO:0006376	mRNA splice site selection	3/319	49/18722	0.0508190317311213	0.141927336580598	SRSF5/RNU11/YTHDC1	3
GO:0030857	negative regulation of epithelial cell differentiation	3/319	49/18722	0.0508190317311213	0.141927336580598	VEGFA/CTNNB1/HES1	3
GO:0042304	regulation of fatty acid biosynthetic process	3/319	49/18722	0.0508190317311213	0.141927336580598	IL1B/PTGS2/APOC1	3
GO:0043330	response to exogenous dsRNA	3/319	49/18722	0.0508190317311213	0.141927336580598	NFKBIA/RIPK2/IFIT1	3
GO:0060986	endocrine hormone secretion	3/319	49/18722	0.0508190317311213	0.141927336580598	IL1B/HCAR2/RETN	3
GO:0070849	response to epidermal growth factor	3/319	49/18722	0.0508190317311213	0.141927336580598	NCL/ZFP36/EEF1A1	3
GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	3/319	49/18722	0.0508190317311213	0.141927336580598	JUN/TNF/NR4A3	3
GO:1904894	positive regulation of receptor signaling pathway via STAT	3/319	49/18722	0.0508190317311213	0.141927336580598	TNF/HES1/CSH1	3
GO:0006757	ATP generation from ADP	4/319	82/18722	0.0514638355193123	0.142913832194545	DDIT4/HIF1A/LDHA/PGK1	4
GO:0007032	endosome organization	4/319	82/18722	0.0514638355193123	0.142913832194545	CHMP1B/CHMP2B/CHMP5/SNX3	4
GO:0046889	positive regulation of lipid biosynthetic process	4/319	82/18722	0.0514638355193123	0.142913832194545	IL1B/TNF/PTGS2/APOE	4
GO:0050000	chromosome localization	4/319	82/18722	0.0514638355193123	0.142913832194545	CHMP1B/CHMP2B/CHMP5/HNRNPU	4
GO:0060395	SMAD protein signal transduction	4/319	82/18722	0.0514638355193123	0.142913832194545	FOS/JUN/ZMIZ1/TOB1	4
GO:1905897	regulation of response to endoplasmic reticulum stress	4/319	82/18722	0.0514638355193123	0.142913832194545	PPP1R15A/PPP1R15B/PMAIP1/ERP29	4
GO:0007613	memory	5/319	118/18722	0.0514851339041891	0.142913832194545	SGK1/PRNP/PTGS2/CEBPB/APOE	5
GO:0009308	amine metabolic process	5/319	118/18722	0.0514851339041891	0.142913832194545	NR4A2/SAT1/SNCA/OAZ1/AOC1	5
GO:0022612	gland morphogenesis	5/319	118/18722	0.0514851339041891	0.142913832194545	TNFAIP3/TNF/AREG/CEBPB/STAT6	5
GO:0008544	epidermis development	10/319	324/18722	0.0517116763726711	0.143445817522302	KLF4/TNF/FOSL2/ZFP36/CTNNB1/EREG/MAFF/HES1/YBX1/HLA-DRB1	10
GO:0031398	positive regulation of protein ubiquitination	5/319	119/18722	0.0530288572174314	0.145393071410346	BIRC3/GABARAP/NPM1/RIPK2/NMI	5
GO:0050672	negative regulation of lymphocyte proliferation	4/319	83/18722	0.0533754943863008	0.145393071410346	PRNP/CEBPB/MNDA/HLA-DRB1	4
GO:0001961	positive regulation of cytokine-mediated signaling pathway	3/319	50/18722	0.05340573750445	0.145393071410346	CXCR4/HIF1A/RIPK2	3
GO:0002448	mast cell mediated immunity	3/319	50/18722	0.05340573750445	0.145393071410346	HMOX1/SERPINB9/NR4A3	3
GO:0060688	regulation of morphogenesis of a branching structure	3/319	50/18722	0.05340573750445	0.145393071410346	VEGFA/TNF/CTNNB1	3
GO:0070231	T cell apoptotic process	3/319	50/18722	0.05340573750445	0.145393071410346	HIF1A/TSC22D3/RPS6	3
GO:1902930	regulation of alcohol biosynthetic process	3/319	50/18722	0.05340573750445	0.145393071410346	SNCA/PLEK/APOE	3
GO:1904036	negative regulation of epithelial cell apoptotic process	3/319	50/18722	0.05340573750445	0.145393071410346	TNFAIP3/ICAM1/HMOX1	3
GO:2000677	regulation of transcription regulatory region DNA binding	3/319	50/18722	0.05340573750445	0.145393071410346	KLF4/TMSB4X/CTNNB1	3
GO:0007179	transforming growth factor beta receptor signaling pathway	7/319	198/18722	0.0534371566207484	0.145393071410346	FOS/JUN/SKIL/HSP90AB1/ZMIZ1/LRG1/THBS1	7
GO:0002053	positive regulation of mesenchymal cell proliferation	2/319	22/18722	0.0534392923622069	0.145393071410346	CTNNB1/IRS2	2
GO:0002220	innate immune response activating cell surface receptor signaling pathway	2/319	22/18722	0.0534392923622069	0.145393071410346	FFAR2/FCN1	2
GO:0007398	ectoderm development	2/319	22/18722	0.0534392923622069	0.145393071410346	CTNNB1/ETS2	2
GO:0010310	regulation of hydrogen peroxide metabolic process	2/319	22/18722	0.0534392923622069	0.145393071410346	SOD2/SNCA	2
GO:0032700	negative regulation of interleukin-17 production	2/319	22/18722	0.0534392923622069	0.145393071410346	PRNP/NCKAP1L	2
GO:0032727	positive regulation of interferon-alpha production	2/319	22/18722	0.0534392923622069	0.145393071410346	RIPK2/HMGB1	2
GO:0032891	negative regulation of organic acid transport	2/319	22/18722	0.0534392923622069	0.145393071410346	IRS2/THBS1	2
GO:0043371	negative regulation of CD4-positive, alpha-beta T cell differentiation	2/319	22/18722	0.0534392923622069	0.145393071410346	BCL6/HMGB1	2
GO:0044346	fibroblast apoptotic process	2/319	22/18722	0.0534392923622069	0.145393071410346	BTG1/STK17B	2
GO:0051220	cytoplasmic sequestering of protein	2/319	22/18722	0.0534392923622069	0.145393071410346	NFKBIA/TMSB4X	2
GO:0060563	neuroepithelial cell differentiation	2/319	22/18722	0.0534392923622069	0.145393071410346	CEBPB/HES1	2
GO:0060965	negative regulation of gene silencing by miRNA	2/319	22/18722	0.0534392923622069	0.145393071410346	TNF/PPP3CA	2
GO:0071359	cellular response to dsRNA	2/319	22/18722	0.0534392923622069	0.145393071410346	NPM1/IFIT1	2
GO:0072574	hepatocyte proliferation	2/319	22/18722	0.0534392923622069	0.145393071410346	TNFAIP3/CEBPB	2
GO:0072575	epithelial cell proliferation involved in liver morphogenesis	2/319	22/18722	0.0534392923622069	0.145393071410346	TNFAIP3/CEBPB	2
GO:0140467	integrated stress response signaling	2/319	22/18722	0.0534392923622069	0.145393071410346	PPP1R15A/PPP1R15B	2
GO:1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	2/319	22/18722	0.0534392923622069	0.145393071410346	HIF1A/VEGFA	2
GO:1903589	positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	2/319	22/18722	0.0534392923622069	0.145393071410346	VEGFA/HMOX1	2
GO:2000773	negative regulation of cellular senescence	2/319	22/18722	0.0534392923622069	0.145393071410346	BCL6/YBX1	2
GO:0032886	regulation of microtubule-based process	8/319	240/18722	0.0538637600531628	0.146451003689519	CHMP1B/CHMP2B/MAPRE1/CHMP5/NPM1/SNCA/HNRNPU/DEFB1	8
GO:0007052	mitotic spindle organization	5/319	120/18722	0.0545993124387402	0.148156946162152	CHMP1B/CHMP2B/CHMP5/SBDS/HNRNPU	5
GO:0032411	positive regulation of transporter activity	5/319	120/18722	0.0545993124387402	0.148156946162152	TMSB4X/SGK1/ATP1B3/VMP1/IFNGR2	5
GO:0048675	axon extension	5/319	120/18722	0.0545993124387402	0.148156946162152	FN1/VEGFA/SEMA4D/HSP90AB1/APOE	5
GO:0044843	cell cycle G1/S phase transition	8/319	241/18722	0.054930286186695	0.14885854087904	KLF4/CDKN1A/ID2/TMEM14B/RGCC/RPS6/PIAS1/PPP3CA	8
GO:0071824	protein-DNA complex subunit organization	8/319	241/18722	0.054930286186695	0.14885854087904	ANP32B/HMGB2/NPM1/SET/RPL23/NAP1L1/HMGB1/PIAS1	8
GO:0032945	negative regulation of mononuclear cell proliferation	4/319	84/18722	0.0553253218163748	0.149633156570472	PRNP/CEBPB/MNDA/HLA-DRB1	4
GO:0045445	myoblast differentiation	4/319	84/18722	0.0553253218163748	0.149633156570472	TNF/IFRD1/DDX5/BTG1	4
GO:1900542	regulation of purine nucleotide metabolic process	4/319	84/18722	0.0553253218163748	0.149633156570472	TMSB4X/DDIT4/HIF1A/SNCA	4
GO:0006120	mitochondrial electron transport, NADH to ubiquinone	3/319	51/18722	0.0560546219289459	0.151406406537383	SNCA/NDUFS5/NDUFA6	3
GO:0009948	anterior/posterior axis specification	3/319	51/18722	0.0560546219289459	0.151406406537383	CTNNB1/ETS2/BASP1	3
GO:0038127	ERBB signaling pathway	5/319	121/18722	0.0561964980446981	0.151590422218999	PLAUR/HBEGF/AREG/GRB2/EREG	5
GO:0043500	muscle adaptation	5/319	121/18722	0.0561964980446981	0.151590422218999	KLF4/IL1B/HMOX1/NR4A3/PPP3CA	5
GO:0051054	positive regulation of DNA metabolic process	7/319	201/18722	0.0570277565069347	0.153631131716913	KLF4/HNRNPA1/CTNNB1/HSP90AB1/RGCC/HMGB1/STAT6	7
GO:0065004	protein-DNA complex assembly	7/319	201/18722	0.0570277565069347	0.153631131716913	ANP32B/HMGB2/NPM1/SET/NAP1L1/HMGB1/PIAS1	7
GO:0001656	metanephros development	4/319	85/18722	0.0573131906149561	0.154097139710977	CTNNB1/BASP1/EGR1/HES1	4
GO:0032092	positive regulation of protein binding	4/319	85/18722	0.0573131906149561	0.154097139710977	MAPRE1/RIPK2/HSP90AB1/APOE	4
GO:0055072	iron ion homeostasis	4/319	85/18722	0.0573131906149561	0.154097139710977	HIF1A/SLC25A37/FTH1/HMOX1	4
GO:0001919	regulation of receptor recycling	2/319	23/18722	0.0578867685689782	0.154227158513979	CHMP5/SNCA	2
GO:0002758	innate immune response-activating signal transduction	2/319	23/18722	0.0578867685689782	0.154227158513979	FFAR2/FCN1	2
GO:0010888	negative regulation of lipid storage	2/319	23/18722	0.0578867685689782	0.154227158513979	NFKBIA/TNF	2
GO:0035162	embryonic hemopoiesis	2/319	23/18722	0.0578867685689782	0.154227158513979	HIF1A/VEGFA	2
GO:0045723	positive regulation of fatty acid biosynthetic process	2/319	23/18722	0.0578867685689782	0.154227158513979	IL1B/PTGS2	2
GO:0050765	negative regulation of phagocytosis	2/319	23/18722	0.0578867685689782	0.154227158513979	SNX3/HMGB1	2
GO:0060353	regulation of cell adhesion molecule production	2/319	23/18722	0.0578867685689782	0.154227158513979	CXCL8/IL1B	2
GO:0060396	growth hormone receptor signaling pathway	2/319	23/18722	0.0578867685689782	0.154227158513979	STAT6/CSH1	2
GO:0060547	negative regulation of necrotic cell death	2/319	23/18722	0.0578867685689782	0.154227158513979	BIRC3/YBX3	2
GO:0060575	intestinal epithelial cell differentiation	2/319	23/18722	0.0578867685689782	0.154227158513979	HIF1A/CDKN1A	2
GO:0071636	positive regulation of transforming growth factor beta production	2/319	23/18722	0.0578867685689782	0.154227158513979	PTGS2/THBS1	2
GO:0072576	liver morphogenesis	2/319	23/18722	0.0578867685689782	0.154227158513979	TNFAIP3/CEBPB	2
GO:1903306	negative regulation of regulated secretory pathway	2/319	23/18722	0.0578867685689782	0.154227158513979	HMOX1/NCKAP1L	2
GO:2000737	negative regulation of stem cell differentiation	2/319	23/18722	0.0578867685689782	0.154227158513979	HNRNPU/HES1	2
GO:0140014	mitotic nuclear division	9/319	287/18722	0.0580807220993641	0.154643684294356	DUSP1/IL1B/CHMP1B/CHMP2B/CHMP5/HNRNPU/EREG/RGCC/IL1A	9
GO:0006898	receptor-mediated endocytosis	8/319	244/18722	0.0582105143344947	0.154812515529142	CXCL8/VEGFA/GRB2/SNCA/CD81/APOE/C3/APOC1	8
GO:0009913	epidermal cell differentiation	7/319	202/18722	0.0582571056977822	0.154812515529142	KLF4/FOSL2/ZFP36/CTNNB1/EREG/MAFF/HES1	7
GO:0032388	positive regulation of intracellular transport	7/319	202/18722	0.0582571056977822	0.154812515529142	IL1B/ANP32B/PRNP/PTGS2/OAZ1/HSP90AB1/CD81	7
GO:0006816	calcium ion transport	12/319	422/18722	0.0586329444594756	0.155658996204028	CCL3/CCL4/CXCR4/ICAM1/SARAF/PDE4B/CTNNB1/PRNP/VMP1/SNCA/PTGS2/PPP3CA	12
GO:0010718	positive regulation of epithelial to mesenchymal transition	3/319	52/18722	0.0587649628092074	0.155658996204028	IL1B/CTNNB1/RGCC	3
GO:0035196	production of miRNAs involved in gene silencing by miRNA	3/319	52/18722	0.0587649628092074	0.155658996204028	TNF/DDX5/PPP3CA	3
GO:0071357	cellular response to type I interferon	3/319	52/18722	0.0587649628092074	0.155658996204028	HSP90AB1/ISG15/IFIT1	3
GO:1903426	regulation of reactive oxygen species biosynthetic process	3/319	52/18722	0.0587649628092074	0.155658996204028	SOD2/SNCA/PAGE4	3
GO:0006140	regulation of nucleotide metabolic process	4/319	86/18722	0.0593389584167761	0.156876178811168	TMSB4X/DDIT4/HIF1A/SNCA	4
GO:0014031	mesenchymal cell development	4/319	86/18722	0.0593389584167761	0.156876178811168	FN1/HIF1A/SEMA4D/HES1	4
GO:0048864	stem cell development	4/319	86/18722	0.0593389584167761	0.156876178811168	FN1/HIF1A/SEMA4D/HES1	4
GO:0060541	respiratory system development	7/319	203/18722	0.0595027436163932	0.157208084194725	VEGFA/TNF/CTNNB1/BASP1/KLF2/HES1/HMGB1	7
GO:0071322	cellular response to carbohydrate stimulus	6/319	163/18722	0.0606867897431845	0.160233392828665	PIM3/HIF1A/ICAM1/IRS2/HLA-DRB1/PPP3CA	6
GO:1901888	regulation of cell junction assembly	7/319	204/18722	0.0607646946173495	0.160336110123186	IL1B/VEGFA/TNF/LIMS1/SNCA/SEMA4D/THBS1	7
GO:0030900	forebrain development	11/319	379/18722	0.0608977520768578	0.160584130075666	NR4A2/BCL2A1/PHACTR1/CXCR4/HIF1A/KDM6B/CTNNB1/ID2/TMEM14B/ZMIZ1/HES1	11
GO:0034504	protein localization to nucleus	9/319	290/18722	0.0611832205386013	0.161233474124481	NFKBIA/DNAJB6/CDKN1A/NPM1/PTGS2/HSP90AB1/HNRNPU/RPL23/PPP3CA	9
GO:0044070	regulation of anion transport	4/319	87/18722	0.0614024680271134	0.161645067319845	IL1B/PRNP/SNCA/CEBPB	4
GO:0032210	regulation of telomere maintenance via telomerase	3/319	53/18722	0.0615360083569831	0.161645067319845	HNRNPA1/CTNNB1/HNRNPU	3
GO:0032784	regulation of DNA-templated transcription, elongation	3/319	53/18722	0.0615360083569831	0.161645067319845	CTNNB1/HNRNPU/HMGN1	3
GO:0034381	plasma lipoprotein particle clearance	3/319	53/18722	0.0615360083569831	0.161645067319845	HMOX1/APOE/APOC1	3
GO:0050819	negative regulation of coagulation	3/319	53/18722	0.0615360083569831	0.161645067319845	ANXA5/APOE/THBS1	3
GO:0050808	synapse organization	12/319	426/18722	0.0620215841200548	0.162097920133102	TNF/CHMP2B/CTNNB1/PRNP/SRGN/SNCA/SEMA4D/TUBA1A/C5AR1/APOE/C3/TUBB	12
GO:0050806	positive regulation of synaptic transmission	6/319	164/18722	0.0621359737142861	0.162097920133102	TNF/PRNP/SNCA/PTGS2/APOE/RETN	6
GO:0060485	mesenchyme development	9/319	291/18722	0.0622405123610416	0.162097920133102	IL1B/FN1/HIF1A/CTNNB1/DDX5/BASP1/SEMA4D/RGCC/HES1	9
GO:0001702	gastrulation with mouth forming second	2/319	24/18722	0.0624575785674614	0.162097920133102	CTNNB1/ETS2	2
GO:0001783	B cell apoptotic process	2/319	24/18722	0.0624575785674614	0.162097920133102	IRS2/BCL6	2
GO:0002438	acute inflammatory response to antigenic stimulus	2/319	24/18722	0.0624575785674614	0.162097920133102	ICAM1/C3	2
GO:0010155	regulation of proton transport	2/319	24/18722	0.0624575785674614	0.162097920133102	TMSB4X/PPIF	2
GO:0021801	cerebral cortex radial glia-guided migration	2/319	24/18722	0.0624575785674614	0.162097920133102	CTNNB1/ZMIZ1	2
GO:0022030	telencephalon glial cell migration	2/319	24/18722	0.0624575785674614	0.162097920133102	CTNNB1/ZMIZ1	2
GO:0031639	plasminogen activation	2/319	24/18722	0.0624575785674614	0.162097920133102	PGK1/THBS1	2
GO:0048641	regulation of skeletal muscle tissue development	2/319	24/18722	0.0624575785674614	0.162097920133102	CTNNB1/YBX3	2
GO:0060149	negative regulation of posttranscriptional gene silencing	2/319	24/18722	0.0624575785674614	0.162097920133102	TNF/PPP3CA	2
GO:0060479	lung cell differentiation	2/319	24/18722	0.0624575785674614	0.162097920133102	CTNNB1/KLF2	2
GO:0060571	morphogenesis of an epithelial fold	2/319	24/18722	0.0624575785674614	0.162097920133102	HIF1A/CTNNB1	2
GO:0060967	negative regulation of gene silencing by RNA	2/319	24/18722	0.0624575785674614	0.162097920133102	TNF/PPP3CA	2
GO:0071378	cellular response to growth hormone stimulus	2/319	24/18722	0.0624575785674614	0.162097920133102	STAT6/CSH1	2
GO:1901984	negative regulation of protein acetylation	2/319	24/18722	0.0624575785674614	0.162097920133102	SNCA/SET	2
GO:2000353	positive regulation of endothelial cell apoptotic process	2/319	24/18722	0.0624575785674614	0.162097920133102	RGCC/THBS1	2
GO:2000679	positive regulation of transcription regulatory region DNA binding	2/319	24/18722	0.0624575785674614	0.162097920133102	KLF4/CTNNB1	2
GO:0051053	negative regulation of DNA metabolic process	5/319	125/18722	0.0628522427771144	0.16301928710203	DUSP1/HNRNPA1/CDKN1A/BCL6/HNRNPU	5
GO:0048863	stem cell differentiation	7/319	206/18722	0.0633376195607271	0.164174624220775	FN1/HIF1A/OSM/CTNNB1/SEMA4D/HNRNPU/HES1	7
GO:0032386	regulation of intracellular transport	10/319	337/18722	0.0638752685143857	0.165463912326805	IL1B/BNIP3L/ANP32B/PRNP/SNX3/PTGS2/OAZ1/HSP90AB1/CD81/MX2	10
GO:0045926	negative regulation of growth	8/319	249/18722	0.0639481360327216	0.165548354679168	HIF1A/CDKN1A/BCL6/BTG1/SEMA4D/PLAC8/SPP1/MT2A	8
GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	3/319	54/18722	0.0643669790063782	0.166109636343516	VEGFA/HMOX1/THBS1	3
GO:0006968	cellular defense response	3/319	54/18722	0.0643669790063782	0.166109636343516	NCF2/MNDA/C5AR1	3
GO:0031050	dsRNA processing	3/319	54/18722	0.0643669790063782	0.166109636343516	TNF/DDX5/PPP3CA	3
GO:0035065	regulation of histone acetylation	3/319	54/18722	0.0643669790063782	0.166109636343516	IL1B/SNCA/SET	3
GO:0070918	production of small RNA involved in gene silencing by RNA	3/319	54/18722	0.0643669790063782	0.166109636343516	TNF/DDX5/PPP3CA	3
GO:0030307	positive regulation of cell growth	6/319	166/18722	0.0650954260309667	0.167884125729802	FN1/CXCR4/VEGFA/HBEGF/SEMA4D/S100A8	6
GO:0071560	cellular response to transforming growth factor beta stimulus	8/319	250/18722	0.065136466587183	0.16788464836358	FOS/JUN/LIMS1/SKIL/HSP90AB1/ZMIZ1/LRG1/THBS1	8
GO:0031664	regulation of lipopolysaccharide-mediated signaling pathway	2/319	25/18722	0.0671462581425168	0.171415878079328	TNFAIP3/TRIB1	2
GO:0032753	positive regulation of interleukin-4 production	2/319	25/18722	0.0671462581425168	0.171415878079328	NLRP3/CEBPB	2
GO:0033119	negative regulation of RNA splicing	2/319	25/18722	0.0671462581425168	0.171415878079328	SRSF7/NPM1	2
GO:0035902	response to immobilization stress	2/319	25/18722	0.0671462581425168	0.171415878079328	FOS/SOD2	2
GO:0042832	defense response to protozoan	2/319	25/18722	0.0671462581425168	0.171415878079328	GBP4/PF4	2
GO:0048143	astrocyte activation	2/319	25/18722	0.0671462581425168	0.171415878079328	TNF/C5AR1	2
GO:0050927	positive regulation of positive chemotaxis	2/319	25/18722	0.0671462581425168	0.171415878079328	CXCL8/VEGFA	2
GO:0060706	cell differentiation involved in embryonic placenta development	2/319	25/18722	0.0671462581425168	0.171415878079328	SOCS3/DNAJB6	2
GO:0072012	glomerulus vasculature development	2/319	25/18722	0.0671462581425168	0.171415878079328	EGR1/HES1	2
GO:0090312	positive regulation of protein deacetylation	2/319	25/18722	0.0671462581425168	0.171415878079328	VEGFA/BCL6	2
GO:0098581	detection of external biotic stimulus	2/319	25/18722	0.0671462581425168	0.171415878079328	HLA-A/HLA-DRB1	2
GO:1901623	regulation of lymphocyte chemotaxis	2/319	25/18722	0.0671462581425168	0.171415878079328	CCL3/CCL4	2
GO:1903901	negative regulation of viral life cycle	2/319	25/18722	0.0671462581425168	0.171415878079328	SNX3/FCN1	2
GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell	2/319	25/18722	0.0671462581425168	0.171415878079328	ICAM1/TNF	2
GO:0001755	neural crest cell migration	3/319	55/18722	0.0672570691661287	0.171415878079328	FN1/HIF1A/SEMA4D	3
GO:0045620	negative regulation of lymphocyte differentiation	3/319	55/18722	0.0672570691661287	0.171415878079328	BCL6/ID2/HMGB1	3
GO:0048016	inositol phosphate-mediated signaling	3/319	55/18722	0.0672570691661287	0.171415878079328	TNF/PRNP/PPP3CA	3
GO:1902991	regulation of amyloid precursor protein catabolic process	3/319	55/18722	0.0672570691661287	0.171415878079328	TNF/PRNP/APOE	3
GO:0034109	homotypic cell-cell adhesion	4/319	90/18722	0.0678176605457218	0.172310508345774	FN1/PLAUR/TLN1/PLEK	4
GO:0046031	ADP metabolic process	4/319	90/18722	0.0678176605457218	0.172310508345774	DDIT4/HIF1A/LDHA/PGK1	4
GO:0048477	oogenesis	4/319	90/18722	0.0678176605457218	0.172310508345774	CTNNB1/YTHDC1/EREG/RPS6	4
GO:0061097	regulation of protein tyrosine kinase activity	4/319	90/18722	0.0678176605457218	0.172310508345774	HBEGF/AREG/PRNP/EREG	4
GO:0099175	regulation of postsynapse organization	4/319	90/18722	0.0678176605457218	0.172310508345774	CHMP2B/PRNP/SRGN/APOE	4
GO:0006334	nucleosome assembly	5/319	129/18722	0.0699335576760784	0.177172867079161	ANP32B/HMGB2/NPM1/SET/NAP1L1	5
GO:0006638	neutral lipid metabolic process	5/319	129/18722	0.0699335576760784	0.177172867079161	SNCA/APOE/C3/DGKZ/APOC1	5
GO:0001657	ureteric bud development	4/319	91/18722	0.0700302809111508	0.177172867079161	VEGFA/CTNNB1/BASP1/HES1	4
GO:0002065	columnar/cuboidal epithelial cell differentiation	4/319	91/18722	0.0700302809111508	0.177172867079161	HIF1A/CDKN1A/CEBPB/HES1	4
GO:0006354	DNA-templated transcription, elongation	4/319	91/18722	0.0700302809111508	0.177172867079161	CTNNB1/HNRNPU/HMGN1/ZMIZ1	4
GO:0014033	neural crest cell differentiation	4/319	91/18722	0.0700302809111508	0.177172867079161	FN1/HIF1A/SEMA4D/HES1	4
GO:0042180	cellular ketone metabolic process	7/319	211/18722	0.0700565874128675	0.177172867079161	IL1B/IRS2/SNCA/PTGS2/EGR1/NR4A3/APOC1	7
GO:0001912	positive regulation of leukocyte mediated cytotoxicity	3/319	56/18722	0.070205448910716	0.177172867079161	HLA-A/HLA-DRA/HLA-DRB1	3
GO:0022029	telencephalon cell migration	3/319	56/18722	0.070205448910716	0.177172867079161	CXCR4/CTNNB1/ZMIZ1	3
GO:0043470	regulation of carbohydrate catabolic process	3/319	56/18722	0.070205448910716	0.177172867079161	DDIT4/HIF1A/HMGB1	3
GO:0045071	negative regulation of viral genome replication	3/319	56/18722	0.070205448910716	0.177172867079161	TNF/ISG15/IFIT1	3
GO:0030336	negative regulation of cell migration	10/319	344/18722	0.0711303179051341	0.179396771109206	KLF4/DUSP1/TRIB1/TNF/HMOX1/PTGER4/RGCC/APOE/HMGB1/THBS1	10
GO:0051656	establishment of organelle localization	11/319	390/18722	0.0714089371040309	0.179989049929289	HIF1A/CHMP1B/CHMP2B/CHMP5/CTNNB1/NPM1/SNCA/HMOX1/HNRNPU/RPS15/NR4A3	11
GO:0007098	centrosome cycle	5/319	130/18722	0.0717699876369712	0.180131633026222	CHMP1B/CHMP2B/CHMP5/CTNNB1/NPM1	5
GO:0001562	response to protozoan	2/319	26/18722	0.0719474924419988	0.180131633026222	GBP4/PF4	2
GO:0001963	synaptic transmission, dopaminergic	2/319	26/18722	0.0719474924419988	0.180131633026222	SNCA/PTGS2	2
GO:0010875	positive regulation of cholesterol efflux	2/319	26/18722	0.0719474924419988	0.180131633026222	NFKBIA/APOE	2
GO:0046639	negative regulation of alpha-beta T cell differentiation	2/319	26/18722	0.0719474924419988	0.180131633026222	BCL6/HMGB1	2
GO:0048668	collateral sprouting	2/319	26/18722	0.0719474924419988	0.180131633026222	SEMA4D/SPP1	2
GO:0050926	regulation of positive chemotaxis	2/319	26/18722	0.0719474924419988	0.180131633026222	CXCL8/VEGFA	2
GO:0060352	cell adhesion molecule production	2/319	26/18722	0.0719474924419988	0.180131633026222	CXCL8/IL1B	2
GO:0060544	regulation of necroptotic process	2/319	26/18722	0.0719474924419988	0.180131633026222	BIRC3/YBX3	2
GO:0072273	metanephric nephron morphogenesis	2/319	26/18722	0.0719474924419988	0.180131633026222	CTNNB1/HES1	2
GO:1900017	positive regulation of cytokine production involved in inflammatory response	2/319	26/18722	0.0719474924419988	0.180131633026222	HIF1A/TNF	2
GO:0031058	positive regulation of histone modification	4/319	92/18722	0.0722796467468064	0.180633208374542	IL1B/VEGFA/CTNNB1/BCL6	4
GO:0072163	mesonephric epithelium development	4/319	92/18722	0.0722796467468064	0.180633208374542	VEGFA/CTNNB1/BASP1/HES1	4
GO:0072164	mesonephric tubule development	4/319	92/18722	0.0722796467468064	0.180633208374542	VEGFA/CTNNB1/BASP1/HES1	4
GO:0071559	response to transforming growth factor beta	8/319	256/18722	0.0725535635512355	0.181207594021342	FOS/JUN/LIMS1/SKIL/HSP90AB1/ZMIZ1/LRG1/THBS1	8
GO:0034205	amyloid-beta formation	3/319	57/18722	0.0732112656120444	0.182406977534009	TNF/PRNP/APOE	3
GO:0060760	positive regulation of response to cytokine stimulus	3/319	57/18722	0.0732112656120444	0.182406977534009	CXCR4/HIF1A/RIPK2	3
GO:0061005	cell differentiation involved in kidney development	3/319	57/18722	0.0732112656120444	0.182406977534009	CTNNB1/BASP1/HES1	3
GO:0061756	leukocyte adhesion to vascular endothelial cell	3/319	57/18722	0.0732112656120444	0.182406977534009	KLF4/ICAM1/TNF	3
GO:0019827	stem cell population maintenance	5/319	131/18722	0.073632716907487	0.183345911088237	KLF4/KLF10/ZNF706/CTNNB1/HES1	5
GO:0001678	cellular glucose homeostasis	6/319	172/18722	0.0744619701101392	0.18499628799116	PIM3/HIF1A/ICAM1/IRS2/HLA-DRB1/PPP3CA	6
GO:0042770	signal transduction in response to DNA damage	6/319	172/18722	0.0744619701101392	0.18499628799116	CDKN1A/GRB2/SYF2/PMAIP1/DDX5/NPM1	6
GO:0033273	response to vitamin	4/319	93/18722	0.0745655191440894	0.18499628799116	SOD2/PIM1/PTGS2/SPP1	4
GO:0045185	maintenance of protein location	4/319	93/18722	0.0745655191440894	0.18499628799116	NFKBIA/TMSB4X/SRGN/HNRNPU	4
GO:0060993	kidney morphogenesis	4/319	93/18722	0.0745655191440894	0.18499628799116	VEGFA/CTNNB1/BASP1/HES1	4
GO:0090398	cellular senescence	4/319	93/18722	0.0745655191440894	0.18499628799116	CDKN1A/BCL6/ID2/YBX1	4
GO:0042593	glucose homeostasis	8/319	258/18722	0.0751355695925447	0.186298146317824	PIM3/HIF1A/ICAM1/IRS2/FFAR2/RPS6/HLA-DRB1/PPP3CA	8
GO:0010469	regulation of signaling receptor activity	6/319	173/18722	0.0760940717581529	0.188145902362709	HIF1A/TNF/HBEGF/AREG/IFNGR2/EREG	6
GO:0007405	neuroblast proliferation	3/319	58/18722	0.0762736455133692	0.188145902362709	HIF1A/VEGFA/CTNNB1	3
GO:0010043	response to zinc ion	3/319	58/18722	0.0762736455133692	0.188145902362709	SOD2/MT2A/S100A8	3
GO:0034340	response to type I interferon	3/319	58/18722	0.0762736455133692	0.188145902362709	HSP90AB1/ISG15/IFIT1	3
GO:0045604	regulation of epidermal cell differentiation	3/319	58/18722	0.0762736455133692	0.188145902362709	ZFP36/MAFF/HES1	3
GO:2000736	regulation of stem cell differentiation	3/319	58/18722	0.0762736455133692	0.188145902362709	OSM/HNRNPU/HES1	3
GO:0033500	carbohydrate homeostasis	8/319	259/18722	0.0764471586746274	0.188145902362709	PIM3/HIF1A/ICAM1/IRS2/FFAR2/RPS6/HLA-DRB1/PPP3CA	8
GO:0000027	ribosomal large subunit assembly	2/319	27/18722	0.0768561124996467	0.188145902362709	RPL3/RPL5	2
GO:0002227	innate immune response in mucosa	2/319	27/18722	0.0768561124996467	0.188145902362709	RPL39/DEFB1	2
GO:0002825	regulation of T-helper 1 type immune response	2/319	27/18722	0.0768561124996467	0.188145902362709	IL1B/RIPK2	2
GO:0009651	response to salt stress	2/319	27/18722	0.0768561124996467	0.188145902362709	TNF/HSP90AB1	2
GO:0010758	regulation of macrophage chemotaxis	2/319	27/18722	0.0768561124996467	0.188145902362709	C5AR1/THBS1	2
GO:0014850	response to muscle activity	2/319	27/18722	0.0768561124996467	0.188145902362709	METRNL/HIF1A	2
GO:0032786	positive regulation of DNA-templated transcription, elongation	2/319	27/18722	0.0768561124996467	0.188145902362709	CTNNB1/HMGN1	2
GO:0034143	regulation of toll-like receptor 4 signaling pathway	2/319	27/18722	0.0768561124996467	0.188145902362709	TNFAIP3/HMGB1	2
GO:0034377	plasma lipoprotein particle assembly	2/319	27/18722	0.0768561124996467	0.188145902362709	APOE/APOC1	2
GO:0036037	CD8-positive, alpha-beta T cell activation	2/319	27/18722	0.0768561124996467	0.188145902362709	HLA-A/NCKAP1L	2
GO:0061437	renal system vasculature development	2/319	27/18722	0.0768561124996467	0.188145902362709	EGR1/HES1	2
GO:0061440	kidney vasculature development	2/319	27/18722	0.0768561124996467	0.188145902362709	EGR1/HES1	2
GO:1902914	regulation of protein polyubiquitination	2/319	27/18722	0.0768561124996467	0.188145902362709	GABARAP/NMI	2
GO:1904357	negative regulation of telomere maintenance via telomere lengthening	2/319	27/18722	0.0768561124996467	0.188145902362709	HNRNPA1/HNRNPU	2
GO:1903035	negative regulation of response to wounding	4/319	94/18722	0.0768876467938094	0.188145902362709	TNF/SPP1/APOE/THBS1	4
GO:0090287	regulation of cellular response to growth factor stimulus	9/319	304/18722	0.0770476922139515	0.188425379352501	IL1B/HIF1A/CTNNB1/SKIL/HSP90AB1/LRG1/TOB1/HES1/THBS1	9
GO:0002377	immunoglobulin production	7/319	216/18722	0.0771856488974701	0.188650536633472	TNF/BCL6/HLA-DPB1/HLA-DQA1/HLA-DRA/STAT6/HLA-DRB1	7
GO:0006997	nucleus organization	5/319	133/18722	0.0774367350052136	0.189039440383868	CHMP1B/CHMP2B/CHMP5/HMGB2/SERBP1	5
GO:1903052	positive regulation of proteolysis involved in cellular protein catabolic process	5/319	133/18722	0.0774367350052136	0.189039440383868	TRIB1/GABARAP/SUMO2/RNF19B/PIAS1	5
GO:0032970	regulation of actin filament-based process	11/319	396/18722	0.0776038872551365	0.189335062614757	TMSB4X/ICAM1/PDE4B/GRB2/MYADM/BRK1/PTGER4/PLEK/RGCC/COTL1/NCKAP1L	11
GO:0008593	regulation of Notch signaling pathway	4/319	95/18722	0.0792457663344257	0.192620070283528	NFKBIA/BCL6/ZMIZ1/HES1	4
GO:0030516	regulation of axon extension	4/319	95/18722	0.0792457663344257	0.192620070283528	FN1/VEGFA/SEMA4D/APOE	4
GO:0032147	activation of protein kinase activity	5/319	134/18722	0.0793778375758844	0.192620070283528	VEGFA/PRNP/RGCC/HMGB1/NCKAP1L	5
GO:0098727	maintenance of cell number	5/319	134/18722	0.0793778375758844	0.192620070283528	KLF4/KLF10/ZNF706/CTNNB1/HES1	5
GO:0002820	negative regulation of adaptive immune response	3/319	59/18722	0.0793916952471113	0.192620070283528	SAMSN1/BCL6/NCKAP1L	3
GO:0021885	forebrain cell migration	3/319	59/18722	0.0793916952471113	0.192620070283528	CXCR4/CTNNB1/ZMIZ1	3
GO:0048010	vascular endothelial growth factor receptor signaling pathway	3/319	59/18722	0.0793916952471113	0.192620070283528	IL1B/HIF1A/VEGFA	3
GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	3/319	59/18722	0.0793916952471113	0.192620070283528	SOCS3/SAMSN1/SEMA4D	3
GO:0022900	electron transport chain	6/319	175/18722	0.0794188808393531	0.192620070283528	CYCS/COX7A2L/SNCA/NCF2/NDUFS5/NDUFA6	6
GO:0048771	tissue remodeling	6/319	175/18722	0.0794188808393531	0.192620070283528	TNFAIP3/HIF1A/CTNNB1/IL1A/SPP1/PPP3CA	6
GO:0001101	response to acid chemical	5/319	135/18722	0.0813448671410477	0.196471462068565	ICAM1/VEGFA/TNF/KLF2/CEBPB	5
GO:0001823	mesonephros development	4/319	96/18722	0.0816396026996117	0.196471462068565	VEGFA/CTNNB1/BASP1/HES1	4
GO:0010769	regulation of cell morphogenesis involved in differentiation	4/319	96/18722	0.0816396026996117	0.196471462068565	MYADM/LIMS1/GBP1/FBLN1	4
GO:0034620	cellular response to unfolded protein	4/319	96/18722	0.0816396026996117	0.196471462068565	ATF3/PPP1R15A/PPP1R15B/SERP1	4
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	2/319	28/18722	0.0818670918325109	0.196471462068565	HLA-C/HLA-A	2
GO:0002507	tolerance induction	2/319	28/18722	0.0818670918325109	0.196471462068565	TNFAIP3/HMGB1	2
GO:0010464	regulation of mesenchymal cell proliferation	2/319	28/18722	0.0818670918325109	0.196471462068565	CTNNB1/IRS2	2
GO:0010818	T cell chemotaxis	2/319	28/18722	0.0818670918325109	0.196471462068565	CCL3/GPR183	2
GO:0010884	positive regulation of lipid storage	2/319	28/18722	0.0818670918325109	0.196471462068565	PLIN2/C3	2
GO:0032958	inositol phosphate biosynthetic process	2/319	28/18722	0.0818670918325109	0.196471462068565	SNCA/PLEK	2
GO:0044331	cell-cell adhesion mediated by cadherin	2/319	28/18722	0.0818670918325109	0.196471462068565	VEGFA/RGCC	2
GO:0045671	negative regulation of osteoclast differentiation	2/319	28/18722	0.0818670918325109	0.196471462068565	CCL3/CTNNB1	2
GO:0045686	negative regulation of glial cell differentiation	2/319	28/18722	0.0818670918325109	0.196471462068565	CTNNB1/HES1	2
GO:0050996	positive regulation of lipid catabolic process	2/319	28/18722	0.0818670918325109	0.196471462068565	IL1B/IRS2	2
GO:0051894	positive regulation of focal adhesion assembly	2/319	28/18722	0.0818670918325109	0.196471462068565	VEGFA/LIMS1	2
GO:0060259	regulation of feeding behavior	2/319	28/18722	0.0818670918325109	0.196471462068565	NR4A3/RETN	2
GO:0090344	negative regulation of cell aging	2/319	28/18722	0.0818670918325109	0.196471462068565	BCL6/YBX1	2
GO:1903671	negative regulation of sprouting angiogenesis	2/319	28/18722	0.0818670918325109	0.196471462068565	KLF2/THBS1	2
GO:0006909	phagocytosis	9/319	308/18722	0.0820032808348972	0.196683481629091	IL1B/TNF/SNX3/NCF2/FCN1/C3/HMGB1/THBS1/NCKAP1L	9
GO:0019731	antibacterial humoral response	3/319	60/18722	0.0825645032981598	0.197798760523738	RPL39/DEFB1/HLA-A	3
GO:0031638	zymogen activation	3/319	60/18722	0.0825645032981598	0.197798760523738	PGK1/RIPK2/THBS1	3
GO:0006333	chromatin assembly or disassembly	6/319	177/18722	0.0828242288995756	0.1981899912725	ANP32B/HMGB2/NPM1/SET/NAP1L1/HMGB1	6
GO:0030324	lung development	6/319	177/18722	0.0828242288995756	0.1981899912725	VEGFA/TNF/CTNNB1/KLF2/HES1/HMGB1	6
GO:0010876	lipid localization	12/319	448/18722	0.0829666573658287	0.198415316132008	NFKBIA/IL1B/PLIN2/TNF/IRS2/FFAR2/SPP1/APOE/C3/THBS1/RETN/APOC1	12
GO:0032868	response to insulin	8/319	264/18722	0.083210957274835	0.198883863579562	SOCS3/IL1B/SRSF5/ICAM1/GRB2/IRS2/EGR1/RETN	8
GO:0043401	steroid hormone mediated signaling pathway	5/319	136/18722	0.0833377139505721	0.199071087769205	YWHAH/DNAJA1/DDX5/ZMIZ1/NR4A3	5
GO:1904356	regulation of telomere maintenance via telomere lengthening	3/319	61/18722	0.0857911414142209	0.204693779659816	HNRNPA1/CTNNB1/HNRNPU	3
GO:2000401	regulation of lymphocyte migration	3/319	61/18722	0.0857911414142209	0.204693779659816	CCL3/CCL4/CCL20	3
GO:0032956	regulation of actin cytoskeleton organization	10/319	357/18722	0.0859377568609179	0.20492466267705	TMSB4X/ICAM1/GRB2/MYADM/BRK1/PTGER4/PLEK/RGCC/COTL1/NCKAP1L	10
GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening	2/319	29/18722	0.0869755431113947	0.205492217086749	ZFP36/TOB1	2
GO:0010955	negative regulation of protein processing	2/319	29/18722	0.0869755431113947	0.205492217086749	PRNP/THBS1	2
GO:0034067	protein localization to Golgi apparatus	2/319	29/18722	0.0869755431113947	0.205492217086749	ARL5B/ARL5A	2
GO:0043153	entrainment of circadian clock by photoperiod	2/319	29/18722	0.0869755431113947	0.205492217086749	BHLHE40/ID2	2
GO:0048679	regulation of axon regeneration	2/319	29/18722	0.0869755431113947	0.205492217086749	KLF4/SPP1	2
GO:0050686	negative regulation of mRNA processing	2/319	29/18722	0.0869755431113947	0.205492217086749	SRSF7/NPM1	2
GO:0051873	killing by host of symbiont cells	2/319	29/18722	0.0869755431113947	0.205492217086749	TREM1/PF4	2
GO:0051883	killing of cells in other organism involved in symbiotic interaction	2/319	29/18722	0.0869755431113947	0.205492217086749	TREM1/PF4	2
GO:0060441	epithelial tube branching involved in lung morphogenesis	2/319	29/18722	0.0869755431113947	0.205492217086749	TNF/CTNNB1	2
GO:0060969	negative regulation of gene silencing	2/319	29/18722	0.0869755431113947	0.205492217086749	TNF/PPP3CA	2
GO:0062098	regulation of programmed necrotic cell death	2/319	29/18722	0.0869755431113947	0.205492217086749	BIRC3/YBX3	2
GO:0071549	cellular response to dexamethasone stimulus	2/319	29/18722	0.0869755431113947	0.205492217086749	DDIT4/ICAM1	2
GO:0090025	regulation of monocyte chemotaxis	2/319	29/18722	0.0869755431113947	0.205492217086749	DUSP1/HMGB1	2
GO:1902430	negative regulation of amyloid-beta formation	2/319	29/18722	0.0869755431113947	0.205492217086749	PRNP/APOE	2
GO:1903318	negative regulation of protein maturation	2/319	29/18722	0.0869755431113947	0.205492217086749	PRNP/THBS1	2
GO:1903902	positive regulation of viral life cycle	2/319	29/18722	0.0869755431113947	0.205492217086749	CHMP2B/HLA-DRB1	2
GO:0032273	positive regulation of protein polymerization	5/319	138/18722	0.0874003880853742	0.206337576719906	ICAM1/MAPRE1/GRB2/BRK1/NCKAP1L	5
GO:0032412	regulation of ion transmembrane transporter activity	8/319	267/18722	0.0874337286903617	0.206337576719906	TMSB4X/YWHAH/ATP1B3/PPIF/PDE4B/PRNP/VMP1/IFNGR2	8
GO:0007033	vacuole organization	6/319	180/18722	0.0880824150675127	0.207749172887289	GABARAPL1/CHMP2B/CHMP5/MAP1LC3B/GABARAP/VMP1	6
GO:0045787	positive regulation of cell cycle	9/319	313/18722	0.0884629912817669	0.208527154334486	IL1B/NPM1/HNRNPU/EREG/RGCC/IL1A/HES1/RPS15A/CCPG1	9
GO:0000045	autophagosome assembly	4/319	99/18722	0.0890324937772432	0.209120221462599	GABARAPL1/MAP1LC3B/GABARAP/VMP1	4
GO:0006165	nucleoside diphosphate phosphorylation	4/319	99/18722	0.0890324937772432	0.209120221462599	DDIT4/HIF1A/LDHA/PGK1	4
GO:0030838	positive regulation of actin filament polymerization	4/319	99/18722	0.0890324937772432	0.209120221462599	ICAM1/GRB2/BRK1/NCKAP1L	4
GO:0032615	interleukin-12 production	3/319	62/18722	0.0890706659647315	0.209120221462599	RIPK2/HMGB1/THBS1	3
GO:0032655	regulation of interleukin-12 production	3/319	62/18722	0.0890706659647315	0.209120221462599	RIPK2/HMGB1/THBS1	3
GO:0032835	glomerulus development	3/319	62/18722	0.0890706659647315	0.209120221462599	BASP1/EGR1/HES1	3
GO:0060675	ureteric bud morphogenesis	3/319	62/18722	0.0890706659647315	0.209120221462599	VEGFA/CTNNB1/HES1	3
GO:0051783	regulation of nuclear division	5/319	139/18722	0.0894699640099132	0.209937797970749	DUSP1/IL1B/EREG/RGCC/IL1A	5
GO:0030323	respiratory tube development	6/319	181/18722	0.0898749623257579	0.210767809538614	VEGFA/TNF/CTNNB1/KLF2/HES1/HMGB1	6
GO:0010001	glial cell differentiation	7/319	225/18722	0.0910480577082376	0.213397129554484	CXCR4/TNF/CTNNB1/ID2/HES1/C5AR1/S100A8	7
GO:0018105	peptidyl-serine phosphorylation	9/319	315/18722	0.0911293111825795	0.213465867961017	DDIT4/SGK1/VEGFA/TNF/OSM/SNCA/RIPK2/PTGS2/HSP90AB1	9
GO:0019218	regulation of steroid metabolic process	4/319	100/18722	0.0915662247849631	0.214245162260093	TNF/EGR1/APOE/APOC1	4
GO:0060840	artery development	4/319	100/18722	0.0915662247849631	0.214245162260093	VEGFA/ZMIZ1/HES1/APOE	4
GO:0061138	morphogenesis of a branching epithelium	6/319	182/18722	0.0916873136404168	0.214406454138654	SOCS3/VEGFA/TNF/AREG/GRB2/CTNNB1	6
GO:0006325	chromatin organization	11/319	409/18722	0.0921569708614437	0.214574447885344	KDM6B/ANP32B/HMGB2/NPM1/DEK/HMGN2/HNRNPU/HMGN1/SET/NAP1L1/HMGB1	11
GO:0034368	protein-lipid complex remodeling	2/319	30/18722	0.092176714902826	0.214574447885344	APOE/APOC1	2
GO:0034369	plasma lipoprotein particle remodeling	2/319	30/18722	0.092176714902826	0.214574447885344	APOE/APOC1	2
GO:0045577	regulation of B cell differentiation	2/319	30/18722	0.092176714902826	0.214574447885344	ID2/NCKAP1L	2
GO:0045948	positive regulation of translational initiation	2/319	30/18722	0.092176714902826	0.214574447885344	PPP1R15A/TNF	2
GO:0046825	regulation of protein export from nucleus	2/319	30/18722	0.092176714902826	0.214574447885344	IL1B/ANP32B	2
GO:1900101	regulation of endoplasmic reticulum unfolded protein response	2/319	30/18722	0.092176714902826	0.214574447885344	PPP1R15A/PPP1R15B	2
GO:2000637	positive regulation of gene silencing by miRNA	2/319	30/18722	0.092176714902826	0.214574447885344	ZFP36/DDX5	2
GO:0031343	positive regulation of cell killing	3/319	63/18722	0.0924021192498184	0.2147343766173	HLA-A/HLA-DRA/HLA-DRB1	3
GO:0072171	mesonephric tubule morphogenesis	3/319	63/18722	0.0924021192498184	0.2147343766173	VEGFA/CTNNB1/HES1	3
GO:2000756	regulation of peptidyl-lysine acetylation	3/319	63/18722	0.0924021192498184	0.2147343766173	IL1B/SNCA/SET	3
GO:0051495	positive regulation of cytoskeleton organization	7/319	226/18722	0.0926695364887923	0.215234160737528	ICAM1/MAPRE1/GRB2/BRK1/PLEK/RGCC/NCKAP1L	7
GO:0016241	regulation of macroautophagy	5/319	141/18722	0.093684918822083	0.217101860923102	HIF1A/BNIP3L/RIPK2/HMOX1/ATP6V1B2	5
GO:0030183	B cell differentiation	5/319	141/18722	0.093684918822083	0.217101860923102	KLF6/GPR183/BCL6/ID2/NCKAP1L	5
GO:0035296	regulation of tube diameter	5/319	141/18722	0.093684918822083	0.217101860923102	ICAM1/SOD2/PTGS2/KLF2/APOE	5
GO:0097746	blood vessel diameter maintenance	5/319	141/18722	0.093684918822083	0.217101860923102	ICAM1/SOD2/PTGS2/KLF2/APOE	5
GO:0046939	nucleotide phosphorylation	4/319	101/18722	0.0941341337961609	0.21801995720339	DDIT4/HIF1A/LDHA/PGK1	4
GO:0032507	maintenance of protein location in cell	3/319	64/18722	0.0957845307607456	0.221075853060544	TMSB4X/SRGN/HNRNPU	3
GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	3/319	64/18722	0.0957845307607456	0.221075853060544	PIM3/HIF1A/HLA-DRB1	3
GO:1903051	negative regulation of proteolysis involved in cellular protein catabolic process	3/319	64/18722	0.0957845307607456	0.221075853060544	HSP90AB1/RPL23/RPL5	3
GO:1903409	reactive oxygen species biosynthetic process	3/319	64/18722	0.0957845307607456	0.221075853060544	SOD2/SNCA/PAGE4	3
GO:0035150	regulation of tube size	5/319	142/18722	0.0958300097674264	0.221075853060544	ICAM1/SOD2/PTGS2/KLF2/APOE	5
GO:0072006	nephron development	5/319	142/18722	0.0958300097674264	0.221075853060544	VEGFA/CTNNB1/BASP1/EGR1/HES1	5
GO:2000045	regulation of G1/S transition of mitotic cell cycle	5/319	142/18722	0.0958300097674264	0.221075853060544	KLF4/CDKN1A/ID2/TMEM14B/RGCC	5
GO:0007204	positive regulation of cytosolic calcium ion concentration	9/319	319/18722	0.0966029130077195	0.222733917764854	CCL3/CXCR4/CCRL2/PRNP/SNCA/PTGER4/C5AR1/FPR3/HMGB1	9
GO:0062014	negative regulation of small molecule metabolic process	4/319	102/18722	0.0967358827422475	0.222915478673419	DDIT4/PLEK/APOE/APOC1	4
GO:0001516	prostaglandin biosynthetic process	2/319	31/18722	0.0974659884810976	0.223221547992085	IL1B/PTGS2	2
GO:0030212	hyaluronan metabolic process	2/319	31/18722	0.0974659884810976	0.223221547992085	IL1B/PIM1	2
GO:0031063	regulation of histone deacetylation	2/319	31/18722	0.0974659884810976	0.223221547992085	VEGFA/BCL6	2
GO:0033238	regulation of cellular amine metabolic process	2/319	31/18722	0.0974659884810976	0.223221547992085	NR4A2/SNCA	2
GO:0046457	prostanoid biosynthetic process	2/319	31/18722	0.0974659884810976	0.223221547992085	IL1B/PTGS2	2
GO:0048710	regulation of astrocyte differentiation	2/319	31/18722	0.0974659884810976	0.223221547992085	ID2/HES1	2
GO:0060148	positive regulation of posttranscriptional gene silencing	2/319	31/18722	0.0974659884810976	0.223221547992085	ZFP36/DDX5	2
GO:0065005	protein-lipid complex assembly	2/319	31/18722	0.0974659884810976	0.223221547992085	APOE/APOC1	2
GO:0071480	cellular response to gamma radiation	2/319	31/18722	0.0974659884810976	0.223221547992085	CDKN1A/EGR1	2
GO:0090183	regulation of kidney development	2/319	31/18722	0.0974659884810976	0.223221547992085	VEGFA/BASP1	2
GO:2000144	positive regulation of DNA-templated transcription, initiation	2/319	31/18722	0.0974659884810976	0.223221547992085	JUN/MED13	2
GO:0031023	microtubule organizing center organization	5/319	143/18722	0.0979999746788496	0.224319541149638	CHMP1B/CHMP2B/CHMP5/CTNNB1/NPM1	5
GO:0031345	negative regulation of cell projection organization	6/319	186/18722	0.0991333254656426	0.225574098153749	YWHAH/PRNP/SEMA4D/SPP1/APOE/PPP3CA	6
GO:0071478	cellular response to radiation	6/319	186/18722	0.0991333254656426	0.225574098153749	CDKN1A/GRB2/NPM1/PTGS2/EGR1/ADIRF	6
GO:1902115	regulation of organelle assembly	6/319	186/18722	0.0991333254656426	0.225574098153749	CHMP1B/TNF/CHMP2B/CHMP5/NPM1/HNRNPU	6
GO:0045453	bone resorption	3/319	65/18722	0.0992169183932577	0.225574098153749	TNFAIP3/CTNNB1/SPP1	3
GO:0045682	regulation of epidermis development	3/319	65/18722	0.0992169183932577	0.225574098153749	ZFP36/MAFF/HES1	3
GO:0048524	positive regulation of viral process	3/319	65/18722	0.0992169183932577	0.225574098153749	CHMP2B/IFIT1/HLA-DRB1	3
GO:0048645	animal organ formation	3/319	65/18722	0.0992169183932577	0.225574098153749	PIM1/CTNNB1/HES1	3
GO:0070936	protein K48-linked ubiquitination	3/319	65/18722	0.0992169183932577	0.225574098153749	TNFAIP3/GABARAP/NMI	3
GO:1905330	regulation of morphogenesis of an epithelium	3/319	65/18722	0.0992169183932577	0.225574098153749	VEGFA/TNF/CTNNB1	3
GO:0045055	regulated exocytosis	7/319	230/18722	0.0993162828131515	0.225574098153749	CCL3/STX11/SNCA/HMOX1/PLEK/NR4A3/NCKAP1L	7
GO:0009135	purine nucleoside diphosphate metabolic process	4/319	103/18722	0.0993711242414109	0.225574098153749	DDIT4/HIF1A/LDHA/PGK1	4
GO:0009179	purine ribonucleoside diphosphate metabolic process	4/319	103/18722	0.0993711242414109	0.225574098153749	DDIT4/HIF1A/LDHA/PGK1	4
GO:0046425	regulation of receptor signaling pathway via JAK-STAT	4/319	103/18722	0.0993711242414109	0.225574098153749	SOCS3/TNF/HES1/CSH1	4
GO:0090277	positive regulation of peptide hormone secretion	4/319	103/18722	0.0993711242414109	0.225574098153749	HIF1A/IRS2/SERP1/HLA-DRB1	4
GO:1905037	autophagosome organization	4/319	103/18722	0.0993711242414109	0.225574098153749	GABARAPL1/MAP1LC3B/GABARAP/VMP1	4
GO:0007612	learning	5/319	144/18722	0.100194655105277	0.227067379899556	FOS/JUN/HIF1A/PTGS2/PIAS1	5
GO:0010821	regulation of mitochondrion organization	5/319	144/18722	0.100194655105277	0.227067379899556	HIF1A/PLAUR/BNIP3L/PPIF/PMAIP1	5
GO:0014065	phosphatidylinositol 3-kinase signaling	5/319	144/18722	0.100194655105277	0.227067379899556	KLF4/FN1/TNF/OSM/SEMA4D	5
GO:0006303	double-strand break repair via nonhomologous end joining	3/319	66/18722	0.102698289615186	0.231022193403541	HMGB2/DEK/HMGB1	3
GO:0050922	negative regulation of chemotaxis	3/319	66/18722	0.102698289615186	0.231022193403541	DUSP1/SEMA4D/THBS1	3
GO:0051893	regulation of focal adhesion assembly	3/319	66/18722	0.102698289615186	0.231022193403541	VEGFA/LIMS1/THBS1	3
GO:0090109	regulation of cell-substrate junction assembly	3/319	66/18722	0.102698289615186	0.231022193403541	VEGFA/LIMS1/THBS1	3
GO:0010743	regulation of macrophage derived foam cell differentiation	2/319	32/18722	0.102838874708947	0.231022193403541	NFKBIA/PF4	2
GO:0019934	cGMP-mediated signaling	2/319	32/18722	0.102838874708947	0.231022193403541	APOE/THBS1	2
GO:0021799	cerebral cortex radially oriented cell migration	2/319	32/18722	0.102838874708947	0.231022193403541	CTNNB1/ZMIZ1	2
GO:0034243	regulation of transcription elongation from RNA polymerase II promoter	2/319	32/18722	0.102838874708947	0.231022193403541	CTNNB1/HNRNPU	2
GO:0034367	protein-containing complex remodeling	2/319	32/18722	0.102838874708947	0.231022193403541	APOE/APOC1	2
GO:0035456	response to interferon-beta	2/319	32/18722	0.102838874708947	0.231022193403541	XAF1/MNDA	2
GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	2/319	32/18722	0.102838874708947	0.231022193403541	TNFAIP3/CDKN1A	2
GO:0048841	regulation of axon extension involved in axon guidance	2/319	32/18722	0.102838874708947	0.231022193403541	VEGFA/SEMA4D	2
GO:0097345	mitochondrial outer membrane permeabilization	2/319	32/18722	0.102838874708947	0.231022193403541	BNIP3L/VDAC2	2
GO:1901532	regulation of hematopoietic progenitor cell differentiation	2/319	32/18722	0.102838874708947	0.231022193403541	OSM/HES1	2
GO:1902235	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	2/319	32/18722	0.102838874708947	0.231022193403541	PMAIP1/ERP29	2
GO:2000515	negative regulation of CD4-positive, alpha-beta T cell activation	2/319	32/18722	0.102838874708947	0.231022193403541	BCL6/HMGB1	2
GO:0040029	regulation of gene expression, epigenetic	4/319	105/18722	0.104740650800426	0.235037563013401	YTHDC1/KLF2/HNRNPU/ZMIZ1	4
GO:2001022	positive regulation of response to DNA damage stimulus	4/319	105/18722	0.104740650800426	0.235037563013401	PMAIP1/DDX5/SKIL/HMGB1	4
GO:0034329	cell junction assembly	11/319	420/18722	0.105682817868206	0.237022402758425	IL1B/FN1/VEGFA/TNF/CTNNB1/LIMS1/VMP1/SNCA/SEMA4D/TLN1/THBS1	11
GO:0006879	cellular iron ion homeostasis	3/319	67/18722	0.106227642589657	0.237467013967417	HIF1A/FTH1/HMOX1	3
GO:0042130	negative regulation of T cell proliferation	3/319	67/18722	0.106227642589657	0.237467013967417	PRNP/CEBPB/HLA-DRB1	3
GO:0048814	regulation of dendrite morphogenesis	3/319	67/18722	0.106227642589657	0.237467013967417	YWHAH/SEMA4D/PPP3CA	3
GO:0050435	amyloid-beta metabolic process	3/319	67/18722	0.106227642589657	0.237467013967417	TNF/PRNP/APOE	3
GO:0070527	platelet aggregation	3/319	67/18722	0.106227642589657	0.237467013967417	FN1/TLN1/PLEK	3
GO:0072665	protein localization to vacuole	3/319	67/18722	0.106227642589657	0.237467013967417	TNFAIP3/CD81/GBP1	3
GO:1902850	microtubule cytoskeleton organization involved in mitosis	5/319	147/18722	0.106925321810524	0.238896738023404	CHMP1B/CHMP2B/CHMP5/SBDS/HNRNPU	5
GO:0009185	ribonucleoside diphosphate metabolic process	4/319	106/18722	0.107474197512848	0.239862337663038	DDIT4/HIF1A/LDHA/PGK1	4
GO:0046620	regulation of organ growth	4/319	106/18722	0.107474197512848	0.239862337663038	PIM1/BASP1/YBX3/SERP1	4
GO:0001881	receptor recycling	2/319	33/18722	0.108291010985474	0.240121006559483	CHMP5/SNCA	2
GO:0009648	photoperiodism	2/319	33/18722	0.108291010985474	0.240121006559483	BHLHE40/ID2	2
GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	2/319	33/18722	0.108291010985474	0.240121006559483	IL1B/HIF1A	2
GO:0046320	regulation of fatty acid oxidation	2/319	33/18722	0.108291010985474	0.240121006559483	IRS2/NR4A3	2
GO:0048333	mesodermal cell differentiation	2/319	33/18722	0.108291010985474	0.240121006559483	KLF4/KDM6B	2
GO:0048730	epidermis morphogenesis	2/319	33/18722	0.108291010985474	0.240121006559483	KLF4/CTNNB1	2
GO:0060260	regulation of transcription initiation from RNA polymerase II promoter	2/319	33/18722	0.108291010985474	0.240121006559483	HMGB1/MED13	2
GO:0070570	regulation of neuron projection regeneration	2/319	33/18722	0.108291010985474	0.240121006559483	KLF4/SPP1	2
GO:0150117	positive regulation of cell-substrate junction organization	2/319	33/18722	0.108291010985474	0.240121006559483	VEGFA/LIMS1	2
GO:1902992	negative regulation of amyloid precursor protein catabolic process	2/319	33/18722	0.108291010985474	0.240121006559483	PRNP/APOE	2
GO:1903146	regulation of autophagy of mitochondrion	2/319	33/18722	0.108291010985474	0.240121006559483	HIF1A/BNIP3L	2
GO:1904030	negative regulation of cyclin-dependent protein kinase activity	2/319	33/18722	0.108291010985474	0.240121006559483	TNFAIP3/CDKN1A	2
GO:0050821	protein stabilization	6/319	191/18722	0.108877066325687	0.241290361005336	ATP1B3/PIM1/NPM1/HSP90AB1/RPL23/RPL5	6
GO:0042698	ovulation cycle	3/319	68/18722	0.109803967255201	0.242820930277639	EGR1/EREG/RETN	3
GO:0042987	amyloid precursor protein catabolic process	3/319	68/18722	0.109803967255201	0.242820930277639	TNF/PRNP/APOE	3
GO:0051148	negative regulation of muscle cell differentiation	3/319	68/18722	0.109803967255201	0.242820930277639	ID2/EREG/YBX1	3
GO:0061912	selective autophagy	3/319	68/18722	0.109803967255201	0.242820930277639	MAP1LC3B/UFC1/RIPK2	3
GO:0044262	cellular carbohydrate metabolic process	8/319	283/18722	0.112018414272606	0.247584785524023	DDIT4/IRS2/PMAIP1/MIDN/SNCA/PLEK/PFKFB3/HMGB1	8
GO:0006368	transcription elongation from RNA polymerase II promoter	3/319	69/18722	0.113426246364026	0.249417083478959	CTNNB1/HNRNPU/ZMIZ1	3
GO:0033344	cholesterol efflux	3/319	69/18722	0.113426246364026	0.249417083478959	NFKBIA/APOE/APOC1	3
GO:0045669	positive regulation of osteoblast differentiation	3/319	69/18722	0.113426246364026	0.249417083478959	JUND/CTNNB1/CEBPB	3
GO:0050688	regulation of defense response to virus	3/319	69/18722	0.113426246364026	0.249417083478959	TNFAIP3/IFIT1/HERC5	3
GO:0050810	regulation of steroid biosynthetic process	3/319	69/18722	0.113426246364026	0.249417083478959	TNF/EGR1/APOE	3
GO:0051966	regulation of synaptic transmission, glutamatergic	3/319	69/18722	0.113426246364026	0.249417083478959	TNF/PTGS2/DGKZ	3
GO:0072659	protein localization to plasma membrane	8/319	284/18722	0.113668752732452	0.249417083478959	ATP1B3/TNF/MYADM/PRNP/RILPL2/CD81/VAMP5/GBP1	8
GO:0007095	mitotic G2 DNA damage checkpoint signaling	2/319	34/18722	0.113818158259919	0.249417083478959	CDKN1A/SYF2	2
GO:0009649	entrainment of circadian clock	2/319	34/18722	0.113818158259919	0.249417083478959	BHLHE40/ID2	2
GO:0014072	response to isoquinoline alkaloid	2/319	34/18722	0.113818158259919	0.249417083478959	FOSB/CXCR4	2
GO:0032212	positive regulation of telomere maintenance via telomerase	2/319	34/18722	0.113818158259919	0.249417083478959	HNRNPA1/CTNNB1	2
GO:0043278	response to morphine	2/319	34/18722	0.113818158259919	0.249417083478959	FOSB/CXCR4	2
GO:0055094	response to lipoprotein particle	2/319	34/18722	0.113818158259919	0.249417083478959	CD81/APOE	2
GO:0070232	regulation of T cell apoptotic process	2/319	34/18722	0.113818158259919	0.249417083478959	HIF1A/TSC22D3	2
GO:0070884	regulation of calcineurin-NFAT signaling cascade	2/319	34/18722	0.113818158259919	0.249417083478959	TNF/PRNP	2
GO:2000352	negative regulation of endothelial cell apoptotic process	2/319	34/18722	0.113818158259919	0.249417083478959	TNFAIP3/ICAM1	2
GO:0071214	cellular response to abiotic stimulus	9/319	331/18722	0.114142348619768	0.249861126291728	IL1B/CDKN1A/GRB2/NPM1/PTGS2/YBX3/PTGER4/EGR1/ADIRF	9
GO:0104004	cellular response to environmental stimulus	9/319	331/18722	0.114142348619768	0.249861126291728	IL1B/CDKN1A/GRB2/NPM1/PTGS2/YBX3/PTGER4/EGR1/ADIRF	9
GO:0032414	positive regulation of ion transmembrane transporter activity	4/319	109/18722	0.115865373297699	0.25336305831215	TMSB4X/ATP1B3/VMP1/IFNGR2	4
GO:0072009	nephron epithelium development	4/319	109/18722	0.115865373297699	0.25336305831215	VEGFA/CTNNB1/BASP1/HES1	4
GO:1904064	positive regulation of cation transmembrane transport	5/319	151/18722	0.116234997749265	0.254036191253179	TMSB4X/ATP1B3/VMP1/SNCA/IFNGR2	5
GO:0045123	cellular extravasation	3/319	70/18722	0.117093456479704	0.255776407857633	ICAM1/TNF/PTGER4	3
GO:0030509	BMP signaling pathway	5/319	152/18722	0.118621051449102	0.258787554259384	DDX5/SKIL/EGR1/TOB1/HES1	5
GO:0001763	morphogenesis of a branching structure	6/319	196/18722	0.119094402718272	0.258787554259384	SOCS3/VEGFA/TNF/AREG/GRB2/CTNNB1	6
GO:0043393	regulation of protein binding	6/319	196/18722	0.119094402718272	0.258787554259384	CDKN1A/MAPRE1/RIPK2/HSP90AB1/APOE/IFIT1	6
GO:0001569	branching involved in blood vessel morphogenesis	2/319	35/18722	0.119416198109961	0.258787554259384	VEGFA/CTNNB1	2
GO:0010837	regulation of keratinocyte proliferation	2/319	35/18722	0.119416198109961	0.258787554259384	ZFP36/AREG	2
GO:0018149	peptide cross-linking	2/319	35/18722	0.119416198109961	0.258787554259384	FN1/THBS1	2
GO:0021955	central nervous system neuron axonogenesis	2/319	35/18722	0.119416198109961	0.258787554259384	NR4A2/HSP90AB1	2
GO:0032205	negative regulation of telomere maintenance	2/319	35/18722	0.119416198109961	0.258787554259384	HNRNPA1/HNRNPU	2
GO:0032350	regulation of hormone metabolic process	2/319	35/18722	0.119416198109961	0.258787554259384	HIF1A/EGR1	2
GO:0035633	maintenance of blood-brain barrier	2/319	35/18722	0.119416198109961	0.258787554259384	VEGFA/PTGS2	2
GO:0043243	positive regulation of protein-containing complex disassembly	2/319	35/18722	0.119416198109961	0.258787554259384	TNF/PLEK	2
GO:0045907	positive regulation of vasoconstriction	2/319	35/18722	0.119416198109961	0.258787554259384	ICAM1/PTGS2	2
GO:0046627	negative regulation of insulin receptor signaling pathway	2/319	35/18722	0.119416198109961	0.258787554259384	SOCS3/IL1B	2
GO:0070536	protein K63-linked deubiquitination	2/319	35/18722	0.119416198109961	0.258787554259384	TNFAIP3/OTUD1	2
GO:0106056	regulation of calcineurin-mediated signaling	2/319	35/18722	0.119416198109961	0.258787554259384	TNF/PRNP	2
GO:0000281	mitotic cytokinesis	3/319	71/18722	0.120804568935454	0.261245440764677	CHMP1B/CHMP2B/CHMP5	3
GO:0050818	regulation of coagulation	3/319	71/18722	0.120804568935454	0.261245440764677	ANXA5/APOE/THBS1	3
GO:0072078	nephron tubule morphogenesis	3/319	71/18722	0.120804568935454	0.261245440764677	VEGFA/CTNNB1/HES1	3
GO:0150116	regulation of cell-substrate junction organization	3/319	71/18722	0.120804568935454	0.261245440764677	VEGFA/LIMS1/THBS1	3
GO:0008360	regulation of cell shape	5/319	154/18722	0.123462104941869	0.266571803264718	CCL3/FN1/ICAM1/VEGFA/SEMA4D	5
GO:0016052	carbohydrate catabolic process	5/319	154/18722	0.123462104941869	0.266571803264718	DDIT4/HIF1A/LDHA/PGK1/HMGB1	5
GO:0050770	regulation of axonogenesis	5/319	154/18722	0.123462104941869	0.266571803264718	FN1/VEGFA/SKIL/SEMA4D/SPP1	5
GO:0048640	negative regulation of developmental growth	4/319	112/18722	0.124533958001667	0.268354567426366	CDKN1A/SEMA4D/PLAC8/SPP1	4
GO:0042246	tissue regeneration	3/319	72/18722	0.124558550754207	0.268354567426366	CDKN1A/CD81/PPP3CA	3
GO:0071479	cellular response to ionizing radiation	3/319	72/18722	0.124558550754207	0.268354567426366	CDKN1A/GRB2/EGR1	3
GO:0002691	regulation of cellular extravasation	2/319	36/18722	0.125081129883205	0.268354567426366	ICAM1/PTGER4	2
GO:0035774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	2/319	36/18722	0.125081129883205	0.268354567426366	HIF1A/HLA-DRB1	2
GO:0045191	regulation of isotype switching	2/319	36/18722	0.125081129883205	0.268354567426366	BCL6/STAT6	2
GO:0045652	regulation of megakaryocyte differentiation	2/319	36/18722	0.125081129883205	0.268354567426366	HMGB2/PF4	2
GO:0045746	negative regulation of Notch signaling pathway	2/319	36/18722	0.125081129883205	0.268354567426366	NFKBIA/BCL6	2
GO:0060338	regulation of type I interferon-mediated signaling pathway	2/319	36/18722	0.125081129883205	0.268354567426366	HSP90AB1/ISG15	2
GO:0070873	regulation of glycogen metabolic process	2/319	36/18722	0.125081129883205	0.268354567426366	IRS2/HMGB1	2
GO:0071402	cellular response to lipoprotein particle stimulus	2/319	36/18722	0.125081129883205	0.268354567426366	CD81/APOE	2
GO:0097009	energy homeostasis	2/319	36/18722	0.125081129883205	0.268354567426366	METRNL/NR4A3	2
GO:0018209	peptidyl-serine modification	9/319	338/18722	0.125136391572937	0.268354567426366	DDIT4/SGK1/VEGFA/TNF/OSM/SNCA/RIPK2/PTGS2/HSP90AB1	9
GO:0006323	DNA packaging	6/319	199/18722	0.125446437540419	0.268879199545706	ANP32B/HMGB2/NPM1/SET/NAP1L1/HMGB1	6
GO:0051147	regulation of muscle cell differentiation	5/319	155/18722	0.125916682015209	0.269746471998188	SOD2/ID2/EREG/YBX1/PIAS1	5
GO:0045216	cell-cell junction organization	6/319	200/18722	0.127599997393856	0.273210202753199	IL1B/VEGFA/TNF/CTNNB1/LIMS1/TLN1	6
GO:0002637	regulation of immunoglobulin production	3/319	73/18722	0.128354365531595	0.274396670151008	TNF/BCL6/STAT6	3
GO:0035773	insulin secretion involved in cellular response to glucose stimulus	3/319	73/18722	0.128354365531595	0.274396670151008	PIM3/HIF1A/HLA-DRB1	3
GO:0072088	nephron epithelium morphogenesis	3/319	73/18722	0.128354365531595	0.274396670151008	VEGFA/CTNNB1/HES1	3
GO:0072503	cellular divalent inorganic cation homeostasis	12/319	486/18722	0.12851935203544	0.274606578075723	CCL3/CXCR4/CCRL2/PRNP/SNCA/PTGER4/C5AR1/APOE/MT2A/S100A8/FPR3/HMGB1	12
GO:0002244	hematopoietic progenitor cell differentiation	4/319	114/18722	0.130461600316509	0.277228488484334	SBDS/OSM/PLEK/HES1	4
GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	4/319	114/18722	0.130461600316509	0.277228488484334	HSP90AB1/LRG1/HES1/THBS1	4
GO:1904892	regulation of receptor signaling pathway via STAT	4/319	114/18722	0.130461600316509	0.277228488484334	SOCS3/TNF/HES1/CSH1	4
GO:0016202	regulation of striated muscle tissue development	2/319	37/18722	0.130809067900572	0.277228488484334	CTNNB1/YBX3	2
GO:0021532	neural tube patterning	2/319	37/18722	0.130809067900572	0.277228488484334	TMEM107/HES1	2
GO:0033120	positive regulation of RNA splicing	2/319	37/18722	0.130809067900572	0.277228488484334	SRSF5/NCL	2
GO:0040036	regulation of fibroblast growth factor receptor signaling pathway	2/319	37/18722	0.130809067900572	0.277228488484334	CTNNB1/THBS1	2
GO:0043403	skeletal muscle tissue regeneration	2/319	37/18722	0.130809067900572	0.277228488484334	CD81/PPP3CA	2
GO:0048846	axon extension involved in axon guidance	2/319	37/18722	0.130809067900572	0.277228488484334	VEGFA/SEMA4D	2
GO:0060416	response to growth hormone	2/319	37/18722	0.130809067900572	0.277228488484334	STAT6/CSH1	2
GO:0090218	positive regulation of lipid kinase activity	2/319	37/18722	0.130809067900572	0.277228488484334	CD81/DGKZ	2
GO:1900077	negative regulation of cellular response to insulin stimulus	2/319	37/18722	0.130809067900572	0.277228488484334	SOCS3/IL1B	2
GO:1902284	neuron projection extension involved in neuron projection guidance	2/319	37/18722	0.130809067900572	0.277228488484334	VEGFA/SEMA4D	2
GO:1904358	positive regulation of telomere maintenance via telomere lengthening	2/319	37/18722	0.130809067900572	0.277228488484334	HNRNPA1/CTNNB1	2
GO:1905332	positive regulation of morphogenesis of an epithelium	2/319	37/18722	0.130809067900572	0.277228488484334	VEGFA/CTNNB1	2
GO:0001837	epithelial to mesenchymal transition	5/319	157/18722	0.130892847518388	0.277228488484334	IL1B/HIF1A/CTNNB1/DDX5/RGCC	5
GO:0051017	actin filament bundle assembly	5/319	157/18722	0.130892847518388	0.277228488484334	PHACTR1/PTGER4/PLEK/RGCC/MARCKS	5
GO:0050804	modulation of chemical synaptic transmission	11/319	439/18722	0.131631843648686	0.278650107744464	IL1B/YWHAH/TNF/PRNP/SRGN/SNCA/PTGS2/APOE/DGKZ/RETN/PPP3CA	11
GO:0000819	sister chromatid segregation	6/319	202/18722	0.13196066561048	0.279202417048215	DUSP1/CHMP1B/CHMP2B/CHMP5/CTNNB1/HNRNPU	6
GO:0046323	glucose import	3/319	74/18722	0.132190974282971	0.279402105541025	TNF/IRS2/SLC2A3	3
GO:0051881	regulation of mitochondrial membrane potential	3/319	74/18722	0.132190974282971	0.279402105541025	BNIP3L/PRDX3/PMAIP1	3
GO:0099177	regulation of trans-synaptic signaling	11/319	440/18722	0.13308667061125	0.281150720905882	IL1B/YWHAH/TNF/PRNP/SRGN/SNCA/PTGS2/APOE/DGKZ/RETN/PPP3CA	11
GO:0034121	regulation of toll-like receptor signaling pathway	3/319	75/18722	0.136067336255535	0.285920131048486	TNFAIP3/BIRC3/HMGB1	3
GO:0043627	response to estrogen	3/319	75/18722	0.136067336255535	0.285920131048486	LDHA/HMOX1/SERPINB9	3
GO:0061333	renal tubule morphogenesis	3/319	75/18722	0.136067336255535	0.285920131048486	VEGFA/CTNNB1/HES1	3
GO:1903363	negative regulation of cellular protein catabolic process	3/319	75/18722	0.136067336255535	0.285920131048486	HSP90AB1/RPL23/RPL5	3
GO:0008286	insulin receptor signaling pathway	4/319	116/18722	0.13650409988534	0.285920131048486	SOCS3/IL1B/GRB2/IRS2	4
GO:0030518	intracellular steroid hormone receptor signaling pathway	4/319	116/18722	0.13650409988534	0.285920131048486	YWHAH/DNAJA1/DDX5/ZMIZ1	4
GO:0035967	cellular response to topologically incorrect protein	4/319	116/18722	0.13650409988534	0.285920131048486	ATF3/PPP1R15A/PPP1R15B/SERP1	4
GO:0000578	embryonic axis specification	2/319	38/18722	0.136596238720318	0.285920131048486	CTNNB1/BASP1	2
GO:0001825	blastocyst formation	2/319	38/18722	0.136596238720318	0.285920131048486	JUNB/SKIL	2
GO:0006882	cellular zinc ion homeostasis	2/319	38/18722	0.136596238720318	0.285920131048486	MT2A/S100A8	2
GO:0010613	positive regulation of cardiac muscle hypertrophy	2/319	38/18722	0.136596238720318	0.285920131048486	NR4A3/PPP3CA	2
GO:0010742	macrophage derived foam cell differentiation	2/319	38/18722	0.136596238720318	0.285920131048486	NFKBIA/PF4	2
GO:0032373	positive regulation of sterol transport	2/319	38/18722	0.136596238720318	0.285920131048486	NFKBIA/APOE	2
GO:0032376	positive regulation of cholesterol transport	2/319	38/18722	0.136596238720318	0.285920131048486	NFKBIA/APOE	2
GO:0032717	negative regulation of interleukin-8 production	2/319	38/18722	0.136596238720318	0.285920131048486	KLF4/TMSB4X	2
GO:0090077	foam cell differentiation	2/319	38/18722	0.136596238720318	0.285920131048486	NFKBIA/PF4	2
GO:1902110	positive regulation of mitochondrial membrane permeability involved in apoptotic process	2/319	38/18722	0.136596238720318	0.285920131048486	BNIP3L/VDAC2	2
GO:1903580	positive regulation of ATP metabolic process	2/319	38/18722	0.136596238720318	0.285920131048486	TMSB4X/HIF1A	2
GO:0072028	nephron morphogenesis	3/319	76/18722	0.139982409706648	0.292709911650066	VEGFA/CTNNB1/HES1	3
GO:0140029	exocytic process	3/319	76/18722	0.139982409706648	0.292709911650066	STX11/SNCA/PLEK	3
GO:0010639	negative regulation of organelle organization	9/319	347/18722	0.140074528368995	0.292753627923201	DUSP1/TMSB4X/HNRNPA1/PPIF/MAPRE1/MYADM/NPM1/SNCA/HNRNPU	9
GO:0061572	actin filament bundle organization	5/319	161/18722	0.141106865694077	0.294761343937171	PHACTR1/PTGER4/PLEK/RGCC/MARCKS	5
GO:0010463	mesenchymal cell proliferation	2/319	39/18722	0.142438978461444	0.296639635488854	CTNNB1/IRS2	2
GO:0014742	positive regulation of muscle hypertrophy	2/319	39/18722	0.142438978461444	0.296639635488854	NR4A3/PPP3CA	2
GO:0042417	dopamine metabolic process	2/319	39/18722	0.142438978461444	0.296639635488854	NR4A2/SNCA	2
GO:0071548	response to dexamethasone	2/319	39/18722	0.142438978461444	0.296639635488854	DDIT4/ICAM1	2
GO:0090207	regulation of triglyceride metabolic process	2/319	39/18722	0.142438978461444	0.296639635488854	APOE/C3	2
GO:1901861	regulation of muscle tissue development	2/319	39/18722	0.142438978461444	0.296639635488854	CTNNB1/YBX3	2
GO:0051494	negative regulation of cytoskeleton organization	5/319	162/18722	0.143713518681254	0.299142417872727	TMSB4X/MAPRE1/MYADM/NPM1/SNCA	5
GO:0140056	organelle localization by membrane tethering	3/319	77/18722	0.143935152649324	0.299300663905599	STX11/VMP1/PLEK	3
GO:1901983	regulation of protein acetylation	3/319	77/18722	0.143935152649324	0.299300663905599	IL1B/SNCA/SET	3
GO:0006839	mitochondrial transport	7/319	254/18722	0.144414266852414	0.300145121855549	BNIP3L/PPIF/SLC25A37/TOMM22/VDAC2/PMAIP1/TMEM14B	7
GO:0010906	regulation of glucose metabolic process	4/319	119/18722	0.14577545557301	0.302821070167076	IRS2/PMAIP1/MIDN/HMGB1	4
GO:0008306	associative learning	3/319	78/18722	0.147924523565934	0.306510945755824	FOS/HIF1A/PIAS1	3
GO:0032371	regulation of sterol transport	3/319	78/18722	0.147924523565934	0.306510945755824	NFKBIA/APOE/APOC1	3
GO:0032374	regulation of cholesterol transport	3/319	78/18722	0.147924523565934	0.306510945755824	NFKBIA/APOE/APOC1	3
GO:0035050	embryonic heart tube development	3/319	78/18722	0.147924523565934	0.306510945755824	HIF1A/CTNNB1/HES1	3
GO:0061045	negative regulation of wound healing	3/319	78/18722	0.147924523565934	0.306510945755824	TNF/APOE/THBS1	3
GO:0010543	regulation of platelet activation	2/319	40/18722	0.148333730185268	0.306586206531743	PLEK/APOE	2
GO:0031111	negative regulation of microtubule polymerization or depolymerization	2/319	40/18722	0.148333730185268	0.306586206531743	MAPRE1/SNCA	2
GO:0045740	positive regulation of DNA replication	2/319	40/18722	0.148333730185268	0.306586206531743	JUN/EREG	2
GO:0055069	zinc ion homeostasis	2/319	40/18722	0.148333730185268	0.306586206531743	MT2A/S100A8	2
GO:0097352	autophagosome maturation	2/319	40/18722	0.148333730185268	0.306586206531743	MAP1LC3B/VMP1	2
GO:0048593	camera-type eye morphogenesis	4/319	120/18722	0.148919460508674	0.30763102756391	HIF1A/VEGFA/CTNNB1/HMGN1	4
GO:0050680	negative regulation of epithelial cell proliferation	5/319	164/18722	0.148988901941071	0.30763102756391	TNF/EREG/RGCC/APOE/THBS1	5
GO:0051480	regulation of cytosolic calcium ion concentration	9/319	353/18722	0.150520515890135	0.310637470293347	CCL3/CXCR4/CCRL2/PRNP/SNCA/PTGER4/C5AR1/FPR3/HMGB1	9
GO:0071772	response to BMP	5/319	165/18722	0.151657132661262	0.312669243916975	DDX5/SKIL/EGR1/TOB1/HES1	5
GO:0071773	cellular response to BMP stimulus	5/319	165/18722	0.151657132661262	0.312669243916975	DDX5/SKIL/EGR1/TOB1/HES1	5
GO:0000245	spliceosomal complex assembly	3/319	79/18722	0.151949482091078	0.313114947807731	SRSF5/RNU11/YTHDC1	3
GO:0001953	negative regulation of cell-matrix adhesion	2/319	41/18722	0.154277041333968	0.313202947062955	BCL6/THBS1	2
GO:0032735	positive regulation of interleukin-12 production	2/319	41/18722	0.154277041333968	0.313202947062955	RIPK2/HMGB1	2
GO:0042307	positive regulation of protein import into nucleus	2/319	41/18722	0.154277041333968	0.313202947062955	PTGS2/HSP90AB1	2
GO:0048634	regulation of muscle organ development	2/319	41/18722	0.154277041333968	0.313202947062955	CTNNB1/YBX3	2
GO:0071470	cellular response to osmotic stress	2/319	41/18722	0.154277041333968	0.313202947062955	PTGS2/YBX3	2
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	2/319	41/18722	0.154277041333968	0.313202947062955	MYADM/LIMS1	2
GO:1900371	regulation of purine nucleotide biosynthetic process	2/319	41/18722	0.154277041333968	0.313202947062955	TMSB4X/SNCA	2
GO:1902904	negative regulation of supramolecular fiber organization	5/319	166/18722	0.154345384419967	0.313202947062955	TMSB4X/MAPRE1/MYADM/SNCA/APOE	5
GO:0051928	positive regulation of calcium ion transport	4/319	122/18722	0.155285038068379	0.313202947062955	CCL3/CCL4/VMP1/SNCA	4
GO:0032204	regulation of telomere maintenance	3/319	80/18722	0.156008989664573	0.313202947062955	HNRNPA1/CTNNB1/HNRNPU	3
GO:0034728	nucleosome organization	5/319	167/18722	0.157053399632064	0.313202947062955	ANP32B/HMGB2/NPM1/SET/NAP1L1	5
GO:0034767	positive regulation of ion transmembrane transport	5/319	167/18722	0.157053399632064	0.313202947062955	TMSB4X/ATP1B3/VMP1/SNCA/IFNGR2	5
GO:1904062	regulation of cation transmembrane transport	9/319	357/18722	0.157694508854823	0.313202947062955	TMSB4X/YWHAH/ATP1B3/PPIF/PDE4B/PRNP/VMP1/SNCA/IFNGR2	9
GO:0001553	luteinization	1/319	10/18722	0.157934738326807	0.313202947062955	RETN	1
GO:0001915	negative regulation of T cell mediated cytotoxicity	1/319	10/18722	0.157934738326807	0.313202947062955	NCKAP1L	1
GO:0002524	hypersensitivity	1/319	10/18722	0.157934738326807	0.313202947062955	C3	1
GO:0002887	negative regulation of myeloid leukocyte mediated immunity	1/319	10/18722	0.157934738326807	0.313202947062955	HMOX1	1
GO:0003330	regulation of extracellular matrix constituent secretion	1/319	10/18722	0.157934738326807	0.313202947062955	RGCC	1
GO:0006283	transcription-coupled nucleotide-excision repair	1/319	10/18722	0.157934738326807	0.313202947062955	HMGN1	1
GO:0007028	cytoplasm organization	1/319	10/18722	0.157934738326807	0.313202947062955	ZMIZ1	1
GO:0009750	response to fructose	1/319	10/18722	0.157934738326807	0.313202947062955	PTGS2	1
GO:0009950	dorsal/ventral axis specification	1/319	10/18722	0.157934738326807	0.313202947062955	CTNNB1	1
GO:0010728	regulation of hydrogen peroxide biosynthetic process	1/319	10/18722	0.157934738326807	0.313202947062955	SOD2	1
GO:0017085	response to insecticide	1/319	10/18722	0.157934738326807	0.313202947062955	UBA52	1
GO:0021903	rostrocaudal neural tube patterning	1/319	10/18722	0.157934738326807	0.313202947062955	HES1	1
GO:0031340	positive regulation of vesicle fusion	1/319	10/18722	0.157934738326807	0.313202947062955	SNCA	1
GO:0031915	positive regulation of synaptic plasticity	1/319	10/18722	0.157934738326807	0.313202947062955	PTGS2	1
GO:0033131	regulation of glucokinase activity	1/319	10/18722	0.157934738326807	0.313202947062955	MIDN	1
GO:0035871	protein K11-linked deubiquitination	1/319	10/18722	0.157934738326807	0.313202947062955	TNFAIP3	1
GO:0036363	transforming growth factor beta activation	1/319	10/18722	0.157934738326807	0.313202947062955	HSP90AB1	1
GO:0040015	negative regulation of multicellular organism growth	1/319	10/18722	0.157934738326807	0.313202947062955	PLAC8	1
GO:0042368	vitamin D biosynthetic process	1/319	10/18722	0.157934738326807	0.313202947062955	TNF	1
GO:0042989	sequestering of actin monomers	1/319	10/18722	0.157934738326807	0.313202947062955	TMSB4X	1
GO:0044848	biological phase	1/319	10/18722	0.157934738326807	0.313202947062955	CTNNB1	1
GO:0045625	regulation of T-helper 1 cell differentiation	1/319	10/18722	0.157934738326807	0.313202947062955	RIPK2	1
GO:0045843	negative regulation of striated muscle tissue development	1/319	10/18722	0.157934738326807	0.313202947062955	YBX3	1
GO:0045898	regulation of RNA polymerase II transcription preinitiation complex assembly	1/319	10/18722	0.157934738326807	0.313202947062955	HMGB1	1
GO:0048262	determination of dorsal/ventral asymmetry	1/319	10/18722	0.157934738326807	0.313202947062955	CTNNB1	1
GO:0048671	negative regulation of collateral sprouting	1/319	10/18722	0.157934738326807	0.313202947062955	SPP1	1
GO:0048672	positive regulation of collateral sprouting	1/319	10/18722	0.157934738326807	0.313202947062955	SEMA4D	1
GO:0050861	positive regulation of B cell receptor signaling pathway	1/319	10/18722	0.157934738326807	0.313202947062955	CD81	1
GO:0051351	positive regulation of ligase activity	1/319	10/18722	0.157934738326807	0.313202947062955	TMSB4X	1
GO:0051409	response to nitrosative stress	1/319	10/18722	0.157934738326807	0.313202947062955	DNAJA1	1
GO:0051918	negative regulation of fibrinolysis	1/319	10/18722	0.157934738326807	0.313202947062955	THBS1	1
GO:0060272	embryonic skeletal joint morphogenesis	1/319	10/18722	0.157934738326807	0.313202947062955	CTNNB1	1
GO:0060439	trachea morphogenesis	1/319	10/18722	0.157934738326807	0.313202947062955	CTNNB1	1
GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development	1/319	10/18722	0.157934738326807	0.313202947062955	CTNNB1	1
GO:0060947	cardiac vascular smooth muscle cell differentiation	1/319	10/18722	0.157934738326807	0.313202947062955	VEGFA	1
GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus	1/319	10/18722	0.157934738326807	0.313202947062955	PIM3	1
GO:0070099	regulation of chemokine-mediated signaling pathway	1/319	10/18722	0.157934738326807	0.313202947062955	HIF1A	1
GO:0070391	response to lipoteichoic acid	1/319	10/18722	0.157934738326807	0.313202947062955	RIPK2	1
GO:0070561	vitamin D receptor signaling pathway	1/319	10/18722	0.157934738326807	0.313202947062955	PIM1	1
GO:0071223	cellular response to lipoteichoic acid	1/319	10/18722	0.157934738326807	0.313202947062955	RIPK2	1
GO:0071803	positive regulation of podosome assembly	1/319	10/18722	0.157934738326807	0.313202947062955	TNF	1
GO:0072124	regulation of glomerular mesangial cell proliferation	1/319	10/18722	0.157934738326807	0.313202947062955	EGR1	1
GO:0072203	cell proliferation involved in metanephros development	1/319	10/18722	0.157934738326807	0.313202947062955	EGR1	1
GO:0090037	positive regulation of protein kinase C signaling	1/319	10/18722	0.157934738326807	0.313202947062955	VEGFA	1
GO:0090209	negative regulation of triglyceride metabolic process	1/319	10/18722	0.157934738326807	0.313202947062955	APOE	1
GO:0090647	modulation of age-related behavioral decline	1/319	10/18722	0.157934738326807	0.313202947062955	PRNP	1
GO:0097250	mitochondrial respirasome assembly	1/319	10/18722	0.157934738326807	0.313202947062955	COX7A2L	1
GO:0140059	dendrite arborization	1/319	10/18722	0.157934738326807	0.313202947062955	PHACTR1	1
GO:0150172	regulation of phosphatidylcholine metabolic process	1/319	10/18722	0.157934738326807	0.313202947062955	APOC1	1
GO:1901203	positive regulation of extracellular matrix assembly	1/319	10/18722	0.157934738326807	0.313202947062955	RGCC	1
GO:1901725	regulation of histone deacetylase activity	1/319	10/18722	0.157934738326807	0.313202947062955	VEGFA	1
GO:1901838	positive regulation of transcription of nucleolar large rRNA by RNA polymerase I	1/319	10/18722	0.157934738326807	0.313202947062955	NCL	1
GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	1/319	10/18722	0.157934738326807	0.313202947062955	PMAIP1	1
GO:1903867	extraembryonic membrane development	1/319	10/18722	0.157934738326807	0.313202947062955	DNAJB6	1
GO:1903980	positive regulation of microglial cell activation	1/319	10/18722	0.157934738326807	0.313202947062955	CCL3	1
GO:1904350	regulation of protein catabolic process in the vacuole	1/319	10/18722	0.157934738326807	0.313202947062955	CD81	1
GO:1904526	regulation of microtubule binding	1/319	10/18722	0.157934738326807	0.313202947062955	MAPRE1	1
GO:1905456	regulation of lymphoid progenitor cell differentiation	1/319	10/18722	0.157934738326807	0.313202947062955	HES1	1
GO:1905941	positive regulation of gonad development	1/319	10/18722	0.157934738326807	0.313202947062955	RETN	1
GO:1990535	neuron projection maintenance	1/319	10/18722	0.157934738326807	0.313202947062955	PRNP	1
GO:2000252	negative regulation of feeding behavior	1/319	10/18722	0.157934738326807	0.313202947062955	RETN	1
GO:2000253	positive regulation of feeding behavior	1/319	10/18722	0.157934738326807	0.313202947062955	NR4A3	1
GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation	1/319	10/18722	0.157934738326807	0.313202947062955	BRK1	1
GO:2000659	regulation of interleukin-1-mediated signaling pathway	1/319	10/18722	0.157934738326807	0.313202947062955	IL1RN	1
GO:2001225	regulation of chloride transport	1/319	10/18722	0.157934738326807	0.313202947062955	PRNP	1
GO:0010811	positive regulation of cell-substrate adhesion	4/319	123/18722	0.158505677484096	0.314183625909894	FN1/VEGFA/MYADM/LIMS1	4
GO:0000070	mitotic sister chromatid segregation	5/319	168/18722	0.159780917793394	0.315089298037159	DUSP1/CHMP1B/CHMP2B/CHMP5/HNRNPU	5
GO:1902806	regulation of cell cycle G1/S phase transition	5/319	168/18722	0.159780917793394	0.315089298037159	KLF4/CDKN1A/ID2/TMEM14B/RGCC	5
GO:2000241	regulation of reproductive process	5/319	168/18722	0.159780917793394	0.315089298037159	DUSP1/VEGFA/CTNNB1/DEFB1/RETN	5
GO:0021954	central nervous system neuron development	3/319	81/18722	0.160102010155489	0.315089298037159	NR4A2/HSP90AB1/ZMIZ1	3
GO:0071260	cellular response to mechanical stimulus	3/319	81/18722	0.160102010155489	0.315089298037159	IL1B/PTGS2/PTGER4	3
GO:0016601	Rac protein signal transduction	2/319	42/18722	0.160265561224933	0.315089298037159	GABARAP/BRK1	2
GO:0021795	cerebral cortex cell migration	2/319	42/18722	0.160265561224933	0.315089298037159	CTNNB1/ZMIZ1	2
GO:0021879	forebrain neuron differentiation	2/319	42/18722	0.160265561224933	0.315089298037159	ZMIZ1/HES1	2
GO:0030808	regulation of nucleotide biosynthetic process	2/319	42/18722	0.160265561224933	0.315089298037159	TMSB4X/SNCA	2
GO:0032691	negative regulation of interleukin-1 beta production	2/319	42/18722	0.160265561224933	0.315089298037159	TNFAIP3/NLRP3	2
GO:0033003	regulation of mast cell activation	2/319	42/18722	0.160265561224933	0.315089298037159	HMOX1/NR4A3	2
GO:0035019	somatic stem cell population maintenance	2/319	42/18722	0.160265561224933	0.315089298037159	KLF10/HES1	2
GO:0045773	positive regulation of axon extension	2/319	42/18722	0.160265561224933	0.315089298037159	FN1/VEGFA	2
GO:0048489	synaptic vesicle transport	2/319	42/18722	0.160265561224933	0.315089298037159	CTNNB1/SNCA	2
GO:0051602	response to electrical stimulus	2/319	42/18722	0.160265561224933	0.315089298037159	NR4A1/SOD2	2
GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis	2/319	42/18722	0.160265561224933	0.315089298037159	KLF4/THBS1	2
GO:1904037	positive regulation of epithelial cell apoptotic process	2/319	42/18722	0.160265561224933	0.315089298037159	RGCC/THBS1	2
GO:0009132	nucleoside diphosphate metabolic process	4/319	124/18722	0.16175092321526	0.317857574253314	DDIT4/HIF1A/LDHA/PGK1	4
GO:0003018	vascular process in circulatory system	7/319	263/18722	0.163487896983791	0.32111741256587	ICAM1/SOD2/VEGFA/PTGS2/KLF2/SLC2A3/APOE	7
GO:0002312	B cell activation involved in immune response	3/319	82/18722	0.164227510458129	0.322416091448599	GPR183/BCL6/STAT6	3
GO:0070585	protein localization to mitochondrion	4/319	125/18722	0.165020301080983	0.323817879591371	BNIP3L/TOMM22/DNAJA1/ISG15	4
GO:0014014	negative regulation of gliogenesis	2/319	43/18722	0.166296038599752	0.324925387207025	CTNNB1/HES1	2
GO:0036230	granulocyte activation	2/319	43/18722	0.166296038599752	0.324925387207025	CXCL8/CCL3	2
GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	2/319	43/18722	0.166296038599752	0.324925387207025	DDIT4/CDKN1A	2
GO:0045981	positive regulation of nucleotide metabolic process	2/319	43/18722	0.166296038599752	0.324925387207025	TMSB4X/HIF1A	2
GO:0046636	negative regulation of alpha-beta T cell activation	2/319	43/18722	0.166296038599752	0.324925387207025	BCL6/HMGB1	2
GO:0060443	mammary gland morphogenesis	2/319	43/18722	0.166296038599752	0.324925387207025	AREG/STAT6	2
GO:1900544	positive regulation of purine nucleotide metabolic process	2/319	43/18722	0.166296038599752	0.324925387207025	TMSB4X/HIF1A	2
GO:1903793	positive regulation of anion transport	2/319	43/18722	0.166296038599752	0.324925387207025	IL1B/CEBPB	2
GO:1904591	positive regulation of protein import	2/319	43/18722	0.166296038599752	0.324925387207025	PTGS2/HSP90AB1	2
GO:0031929	TOR signaling	4/319	126/18722	0.168313334316401	0.325043040064746	DDIT4/HIF1A/RPS6/NCKAP1L	4
GO:0050886	endocrine process	3/319	83/18722	0.168384461060822	0.325043040064746	IL1B/HCAR2/RETN	3
GO:0031589	cell-substrate adhesion	9/319	363/18722	0.168761158442879	0.325043040064746	FN1/VEGFA/MYADM/CTNNB1/BCL6/LIMS1/GBP1/FBLN1/THBS1	9
GO:0001867	complement activation, lectin pathway	1/319	11/18722	0.172290168984875	0.325043040064746	FCN1	1
GO:0002357	defense response to tumor cell	1/319	11/18722	0.172290168984875	0.325043040064746	KLF4	1
GO:0002604	regulation of dendritic cell antigen processing and presentation	1/319	11/18722	0.172290168984875	0.325043040064746	THBS1	1
GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c	1/319	11/18722	0.172290168984875	0.325043040064746	CYCS	1
GO:0006449	regulation of translational termination	1/319	11/18722	0.172290168984875	0.325043040064746	ETF1	1
GO:0006707	cholesterol catabolic process	1/319	11/18722	0.172290168984875	0.325043040064746	APOE	1
GO:0010248	establishment or maintenance of transmembrane electrochemical gradient	1/319	11/18722	0.172290168984875	0.325043040064746	ATP1B3	1
GO:0010269	response to selenium ion	1/319	11/18722	0.172290168984875	0.325043040064746	SOD2	1
GO:0016127	sterol catabolic process	1/319	11/18722	0.172290168984875	0.325043040064746	APOE	1
GO:0021860	pyramidal neuron development	1/319	11/18722	0.172290168984875	0.325043040064746	ZMIZ1	1
GO:0030656	regulation of vitamin metabolic process	1/319	11/18722	0.172290168984875	0.325043040064746	TNF	1
GO:0032000	positive regulation of fatty acid beta-oxidation	1/319	11/18722	0.172290168984875	0.325043040064746	IRS2	1
GO:0032308	positive regulation of prostaglandin secretion	1/319	11/18722	0.172290168984875	0.325043040064746	IL1B	1
GO:0033234	negative regulation of protein sumoylation	1/319	11/18722	0.172290168984875	0.325043040064746	CTNNB1	1
GO:0033625	positive regulation of integrin activation	1/319	11/18722	0.172290168984875	0.325043040064746	PLEK	1
GO:0034163	regulation of toll-like receptor 9 signaling pathway	1/319	11/18722	0.172290168984875	0.325043040064746	HMGB1	1
GO:0034379	very-low-density lipoprotein particle assembly	1/319	11/18722	0.172290168984875	0.325043040064746	APOC1	1
GO:0034776	response to histamine	1/319	11/18722	0.172290168984875	0.325043040064746	AOC1	1
GO:0035246	peptidyl-arginine N-methylation	1/319	11/18722	0.172290168984875	0.325043040064746	PRMT9	1
GO:0035457	cellular response to interferon-alpha	1/319	11/18722	0.172290168984875	0.325043040064746	IFIT3	1
GO:0042167	heme catabolic process	1/319	11/18722	0.172290168984875	0.325043040064746	HMOX1	1
GO:0042447	hormone catabolic process	1/319	11/18722	0.172290168984875	0.325043040064746	SPP1	1
GO:0042789	mRNA transcription by RNA polymerase II	1/319	11/18722	0.172290168984875	0.325043040064746	C5AR1	1
GO:0044068	modulation by symbiont of host cellular process	1/319	11/18722	0.172290168984875	0.325043040064746	SERPINB9	1
GO:0045654	positive regulation of megakaryocyte differentiation	1/319	11/18722	0.172290168984875	0.325043040064746	HMGB2	1
GO:0045793	positive regulation of cell size	1/319	11/18722	0.172290168984875	0.325043040064746	HSP90AB1	1
GO:0046149	pigment catabolic process	1/319	11/18722	0.172290168984875	0.325043040064746	HMOX1	1
GO:0046598	positive regulation of viral entry into host cell	1/319	11/18722	0.172290168984875	0.325043040064746	HLA-DRB1	1
GO:0046643	regulation of gamma-delta T cell activation	1/319	11/18722	0.172290168984875	0.325043040064746	NCKAP1L	1
GO:0048096	chromatin-mediated maintenance of transcription	1/319	11/18722	0.172290168984875	0.325043040064746	ZMIZ1	1
GO:0048635	negative regulation of muscle organ development	1/319	11/18722	0.172290168984875	0.325043040064746	YBX3	1
GO:0051610	serotonin uptake	1/319	11/18722	0.172290168984875	0.325043040064746	SNCA	1
GO:0051798	positive regulation of hair follicle development	1/319	11/18722	0.172290168984875	0.325043040064746	TNF	1
GO:0060742	epithelial cell differentiation involved in prostate gland development	1/319	11/18722	0.172290168984875	0.325043040064746	CTNNB1	1
GO:0060767	epithelial cell proliferation involved in prostate gland development	1/319	11/18722	0.172290168984875	0.325043040064746	CTNNB1	1
GO:0070243	regulation of thymocyte apoptotic process	1/319	11/18722	0.172290168984875	0.325043040064746	HIF1A	1
GO:0070417	cellular response to cold	1/319	11/18722	0.172290168984875	0.325043040064746	NFKBIA	1
GO:0070601	centromeric sister chromatid cohesion	1/319	11/18722	0.172290168984875	0.325043040064746	CTNNB1	1
GO:0070944	neutrophil-mediated killing of bacterium	1/319	11/18722	0.172290168984875	0.325043040064746	TREM1	1
GO:0071044	histone mRNA catabolic process	1/319	11/18722	0.172290168984875	0.325043040064746	SSB	1
GO:0071679	commissural neuron axon guidance	1/319	11/18722	0.172290168984875	0.325043040064746	VEGFA	1
GO:0072110	glomerular mesangial cell proliferation	1/319	11/18722	0.172290168984875	0.325043040064746	EGR1	1
GO:0072173	metanephric tubule morphogenesis	1/319	11/18722	0.172290168984875	0.325043040064746	HES1	1
GO:0072497	mesenchymal stem cell differentiation	1/319	11/18722	0.172290168984875	0.325043040064746	CTNNB1	1
GO:0075294	positive regulation by symbiont of entry into host	1/319	11/18722	0.172290168984875	0.325043040064746	HLA-DRB1	1
GO:0075522	IRES-dependent viral translational initiation	1/319	11/18722	0.172290168984875	0.325043040064746	SSB	1
GO:0090084	negative regulation of inclusion body assembly	1/319	11/18722	0.172290168984875	0.325043040064746	DNAJB6	1
GO:0098792	xenophagy	1/319	11/18722	0.172290168984875	0.325043040064746	RIPK2	1
GO:0098883	synapse pruning	1/319	11/18722	0.172290168984875	0.325043040064746	C3	1
GO:0098935	dendritic transport	1/319	11/18722	0.172290168984875	0.325043040064746	HNRNPU	1
GO:0106072	negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	1/319	11/18722	0.172290168984875	0.325043040064746	PDE4B	1
GO:1900222	negative regulation of amyloid-beta clearance	1/319	11/18722	0.172290168984875	0.325043040064746	TNF	1
GO:1901533	negative regulation of hematopoietic progenitor cell differentiation	1/319	11/18722	0.172290168984875	0.325043040064746	HES1	1
GO:1901862	negative regulation of muscle tissue development	1/319	11/18722	0.172290168984875	0.325043040064746	YBX3	1
GO:1902033	regulation of hematopoietic stem cell proliferation	1/319	11/18722	0.172290168984875	0.325043040064746	PIM1	1
GO:1902093	positive regulation of flagellated sperm motility	1/319	11/18722	0.172290168984875	0.325043040064746	DEFB1	1
GO:1902188	positive regulation of viral release from host cell	1/319	11/18722	0.172290168984875	0.325043040064746	CHMP2B	1
GO:1902667	regulation of axon guidance	1/319	11/18722	0.172290168984875	0.325043040064746	VEGFA	1
GO:1903299	regulation of hexokinase activity	1/319	11/18722	0.172290168984875	0.325043040064746	MIDN	1
GO:2000155	positive regulation of cilium-dependent cell motility	1/319	11/18722	0.172290168984875	0.325043040064746	DEFB1	1
GO:2000644	regulation of receptor catabolic process	1/319	11/18722	0.172290168984875	0.325043040064746	APOE	1
GO:2001053	regulation of mesenchymal cell apoptotic process	1/319	11/18722	0.172290168984875	0.325043040064746	HIF1A	1
GO:0002066	columnar/cuboidal epithelial cell development	2/319	44/18722	0.172365319226744	0.325043040064746	HIF1A/CDKN1A	2
GO:0008542	visual learning	2/319	44/18722	0.172365319226744	0.325043040064746	HIF1A/PIAS1	2
GO:0021762	substantia nigra development	2/319	44/18722	0.172365319226744	0.325043040064746	YWHAH/BASP1	2
GO:0031295	T cell costimulation	2/319	44/18722	0.172365319226744	0.325043040064746	MAP3K8/CD81	2
GO:0032007	negative regulation of TOR signaling	2/319	44/18722	0.172365319226744	0.325043040064746	DDIT4/HIF1A	2
GO:0032881	regulation of polysaccharide metabolic process	2/319	44/18722	0.172365319226744	0.325043040064746	IRS2/HMGB1	2
GO:0042269	regulation of natural killer cell mediated cytotoxicity	2/319	44/18722	0.172365319226744	0.325043040064746	SERPINB9/HLA-A	2
GO:0044058	regulation of digestive system process	2/319	44/18722	0.172365319226744	0.325043040064746	SGK1/TYMP	2
GO:0045124	regulation of bone resorption	2/319	44/18722	0.172365319226744	0.325043040064746	TNFAIP3/SPP1	2
GO:0046006	regulation of activated T cell proliferation	2/319	44/18722	0.172365319226744	0.325043040064746	PRNP/HMGB1	2
GO:1903573	negative regulation of response to endoplasmic reticulum stress	2/319	44/18722	0.172365319226744	0.325043040064746	PPP1R15A/PPP1R15B	2
GO:0031503	protein-containing complex localization	6/319	220/18722	0.174236573174402	0.328421161082057	SRSF3/YTHDC1/NPM1/HNRNPU/SSB/RPS15	6
GO:0001952	regulation of cell-matrix adhesion	4/319	128/18722	0.174968448358006	0.329347660805752	VEGFA/BCL6/LIMS1/THBS1	4
GO:0006639	acylglycerol metabolic process	4/319	128/18722	0.174968448358006	0.329347660805752	APOE/C3/DGKZ/APOC1	4
GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	4/319	128/18722	0.174968448358006	0.329347660805752	SKIL/HSP90AB1/LRG1/THBS1	4
GO:0016311	dephosphorylation	10/319	417/18722	0.176355236104486	0.331806121567754	PPP1R15A/DUSP1/PPP1R15B/TNF/SEMA4D/HSP90AB1/PLEK/PFKFB3/PPP3CA/NCKAP1L	10
GO:0010507	negative regulation of autophagy	3/319	85/18722	0.17678861631913	0.332165448669078	MCL1/SNCA/HMOX1	3
GO:0060021	roof of mouth development	3/319	85/18722	0.17678861631913	0.332165448669078	ANP32B/CSRNP1/TMEM107	3
GO:0097006	regulation of plasma lipoprotein particle levels	3/319	85/18722	0.17678861631913	0.332165448669078	HMOX1/APOE/APOC1	3
GO:0007498	mesoderm development	4/319	129/18722	0.178329564859827	0.333496173799225	KLF4/KDM6B/VEGFA/ETS2	4
GO:0006110	regulation of glycolytic process	2/319	45/18722	0.178470343555898	0.333496173799225	DDIT4/HIF1A	2
GO:0022602	ovulation cycle process	2/319	45/18722	0.178470343555898	0.333496173799225	EREG/RETN	2
GO:0031670	cellular response to nutrient	2/319	45/18722	0.178470343555898	0.333496173799225	PIM1/HMOX1	2
GO:0035987	endodermal cell differentiation	2/319	45/18722	0.178470343555898	0.333496173799225	FN1/CTNNB1	2
GO:0042551	neuron maturation	2/319	45/18722	0.178470343555898	0.333496173799225	NR4A2/C3	2
GO:0046189	phenol-containing compound biosynthetic process	2/319	45/18722	0.178470343555898	0.333496173799225	NR4A2/SNCA	2
GO:0048538	thymus development	2/319	45/18722	0.178470343555898	0.333496173799225	CTNNB1/HES1	2
GO:0048599	oocyte development	2/319	45/18722	0.178470343555898	0.333496173799225	CTNNB1/EREG	2
GO:0060421	positive regulation of heart growth	2/319	45/18722	0.178470343555898	0.333496173799225	PIM1/BASP1	2
GO:1902108	regulation of mitochondrial membrane permeability involved in apoptotic process	2/319	45/18722	0.178470343555898	0.333496173799225	BNIP3L/VDAC2	2
GO:1904646	cellular response to amyloid-beta	2/319	45/18722	0.178470343555898	0.333496173799225	ICAM1/PRNP	2
GO:0009798	axis specification	3/319	86/18722	0.181033784677046	0.334773733748755	CTNNB1/ETS2/BASP1	3
GO:0034103	regulation of tissue remodeling	3/319	86/18722	0.181033784677046	0.334773733748755	TNFAIP3/SPP1/PPP3CA	3
GO:0060761	negative regulation of response to cytokine stimulus	3/319	86/18722	0.181033784677046	0.334773733748755	KLF4/IL1RN/ISG15	3
GO:2001251	negative regulation of chromosome organization	3/319	86/18722	0.181033784677046	0.334773733748755	DUSP1/HNRNPA1/HNRNPU	3
GO:0016042	lipid catabolic process	8/319	320/18722	0.181394566920659	0.334773733748755	IL1B/YWHAH/TNF/IRS2/HCAR2/SPP1/APOE/APOC1	8
GO:0006956	complement activation	4/319	130/18722	0.181712408581188	0.334773733748755	IL1B/RGCC/FCN1/C3	4
GO:0006984	ER-nucleus signaling pathway	2/319	46/18722	0.184608144425157	0.334773733748755	PPP1R15A/PPP1R15B	2
GO:0031057	negative regulation of histone modification	2/319	46/18722	0.184608144425157	0.334773733748755	SNCA/SET	2
GO:0031294	lymphocyte costimulation	2/319	46/18722	0.184608144425157	0.334773733748755	MAP3K8/CD81	2
GO:0031648	protein destabilization	2/319	46/18722	0.184608144425157	0.334773733748755	PRNP/SNCA	2
GO:0033047	regulation of mitotic sister chromatid segregation	2/319	46/18722	0.184608144425157	0.334773733748755	DUSP1/HNRNPU	2
GO:0034198	cellular response to amino acid starvation	2/319	46/18722	0.184608144425157	0.334773733748755	ATF3/CDKN1A	2
GO:0035094	response to nicotine	2/319	46/18722	0.184608144425157	0.334773733748755	TNF/HMOX1	2
GO:0043300	regulation of leukocyte degranulation	2/319	46/18722	0.184608144425157	0.334773733748755	HMOX1/NCKAP1L	2
GO:0043462	regulation of ATPase activity	2/319	46/18722	0.184608144425157	0.334773733748755	ATP1B3/PPIF	2
GO:0044818	mitotic G2/M transition checkpoint	2/319	46/18722	0.184608144425157	0.334773733748755	CDKN1A/SYF2	2
GO:0071827	plasma lipoprotein particle organization	2/319	46/18722	0.184608144425157	0.334773733748755	APOE/APOC1	2
GO:1900271	regulation of long-term synaptic potentiation	2/319	46/18722	0.184608144425157	0.334773733748755	PRNP/APOE	2
GO:0000723	telomere maintenance	4/319	131/18722	0.185116493358312	0.334773733748755	HNRNPA1/CTNNB1/HSP90AB1/HNRNPU	4
GO:1903844	regulation of cellular response to transforming growth factor beta stimulus	4/319	131/18722	0.185116493358312	0.334773733748755	SKIL/HSP90AB1/LRG1/THBS1	4
GO:0098739	import across plasma membrane	5/319	177/18722	0.185161929436954	0.334773733748755	ATP1B3/IRS2/PRNP/SLC2A3/THBS1	5
GO:0048041	focal adhesion assembly	3/319	87/18722	0.185306331700258	0.334773733748755	VEGFA/LIMS1/THBS1	3
GO:0051262	protein tetramerization	3/319	87/18722	0.185306331700258	0.334773733748755	SOD2/SNCA/HLA-DRB1	3
GO:1900182	positive regulation of protein localization to nucleus	3/319	87/18722	0.185306331700258	0.334773733748755	NPM1/PTGS2/HSP90AB1	3
GO:0072594	establishment of protein localization to organelle	10/319	422/18722	0.185412252235049	0.334773733748755	NFKBIA/TNFAIP3/CDKN1A/BNIP3L/TOMM22/DNAJA1/PTGS2/HSP90AB1/RPL23/PPP3CA	10
GO:0001976	nervous system process involved in regulation of systemic arterial blood pressure	1/319	12/18722	0.186401624069788	0.334773733748755	SOD2	1
GO:0002328	pro-B cell differentiation	1/319	12/18722	0.186401624069788	0.334773733748755	HES1	1
GO:0002674	negative regulation of acute inflammatory response	1/319	12/18722	0.186401624069788	0.334773733748755	NLRP3	1
GO:0003306	Wnt signaling pathway involved in heart development	1/319	12/18722	0.186401624069788	0.334773733748755	CTNNB1	1
GO:0003353	positive regulation of cilium movement	1/319	12/18722	0.186401624069788	0.334773733748755	DEFB1	1
GO:0006787	porphyrin-containing compound catabolic process	1/319	12/18722	0.186401624069788	0.334773733748755	HMOX1	1
GO:0009176	pyrimidine deoxyribonucleoside monophosphate metabolic process	1/319	12/18722	0.186401624069788	0.334773733748755	TYMP	1
GO:0009886	post-embryonic animal morphogenesis	1/319	12/18722	0.186401624069788	0.334773733748755	HMGN1	1
GO:0010454	negative regulation of cell fate commitment	1/319	12/18722	0.186401624069788	0.334773733748755	HES1	1
GO:0010623	programmed cell death involved in cell development	1/319	12/18722	0.186401624069788	0.334773733748755	IL1A	1
GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway	1/319	12/18722	0.186401624069788	0.334773733748755	SNCA	1
GO:0010826	negative regulation of centrosome duplication	1/319	12/18722	0.186401624069788	0.334773733748755	NPM1	1
GO:0021781	glial cell fate commitment	1/319	12/18722	0.186401624069788	0.334773733748755	CTNNB1	1
GO:0032306	regulation of prostaglandin secretion	1/319	12/18722	0.186401624069788	0.334773733748755	IL1B	1
GO:0032780	negative regulation of ATPase activity	1/319	12/18722	0.186401624069788	0.334773733748755	PPIF	1
GO:0032908	regulation of transforming growth factor beta1 production	1/319	12/18722	0.186401624069788	0.334773733748755	THBS1	1
GO:0033004	negative regulation of mast cell activation	1/319	12/18722	0.186401624069788	0.334773733748755	HMOX1	1
GO:0033015	tetrapyrrole catabolic process	1/319	12/18722	0.186401624069788	0.334773733748755	HMOX1	1
GO:0033127	regulation of histone phosphorylation	1/319	12/18722	0.186401624069788	0.334773733748755	IL1B	1
GO:0033235	positive regulation of protein sumoylation	1/319	12/18722	0.186401624069788	0.334773733748755	PIAS1	1
GO:0034145	positive regulation of toll-like receptor 4 signaling pathway	1/319	12/18722	0.186401624069788	0.334773733748755	HMGB1	1
GO:0034333	adherens junction assembly	1/319	12/18722	0.186401624069788	0.334773733748755	CTNNB1	1
GO:0034370	triglyceride-rich lipoprotein particle remodeling	1/319	12/18722	0.186401624069788	0.334773733748755	APOE	1
GO:0034372	very-low-density lipoprotein particle remodeling	1/319	12/18722	0.186401624069788	0.334773733748755	APOE	1
GO:0035112	genitalia morphogenesis	1/319	12/18722	0.186401624069788	0.334773733748755	CTNNB1	1
GO:0035739	CD4-positive, alpha-beta T cell proliferation	1/319	12/18722	0.186401624069788	0.334773733748755	CD81	1
GO:0038203	TORC2 signaling	1/319	12/18722	0.186401624069788	0.334773733748755	NCKAP1L	1
GO:0042762	regulation of sulfur metabolic process	1/319	12/18722	0.186401624069788	0.334773733748755	SNCA	1
GO:0043129	surfactant homeostasis	1/319	12/18722	0.186401624069788	0.334773733748755	VEGFA	1
GO:0043471	regulation of cellular carbohydrate catabolic process	1/319	12/18722	0.186401624069788	0.334773733748755	HMGB1	1
GO:0045602	negative regulation of endothelial cell differentiation	1/319	12/18722	0.186401624069788	0.334773733748755	VEGFA	1
GO:0045605	negative regulation of epidermal cell differentiation	1/319	12/18722	0.186401624069788	0.334773733748755	HES1	1
GO:0045683	negative regulation of epidermis development	1/319	12/18722	0.186401624069788	0.334773733748755	HES1	1
GO:0046606	negative regulation of centrosome cycle	1/319	12/18722	0.186401624069788	0.334773733748755	NPM1	1
GO:0051095	regulation of helicase activity	1/319	12/18722	0.186401624069788	0.334773733748755	IFIT1	1
GO:0051340	regulation of ligase activity	1/319	12/18722	0.186401624069788	0.334773733748755	TMSB4X	1
GO:0051549	positive regulation of keratinocyte migration	1/319	12/18722	0.186401624069788	0.334773733748755	HBEGF	1
GO:0051583	dopamine uptake involved in synaptic transmission	1/319	12/18722	0.186401624069788	0.334773733748755	SNCA	1
GO:0051934	catecholamine uptake involved in synaptic transmission	1/319	12/18722	0.186401624069788	0.334773733748755	SNCA	1
GO:0060009	Sertoli cell development	1/319	12/18722	0.186401624069788	0.334773733748755	ICAM1	1
GO:0060019	radial glial cell differentiation	1/319	12/18722	0.186401624069788	0.334773733748755	HES1	1
GO:0060123	regulation of growth hormone secretion	1/319	12/18722	0.186401624069788	0.334773733748755	SERP1	1
GO:0060453	regulation of gastric acid secretion	1/319	12/18722	0.186401624069788	0.334773733748755	SGK1	1
GO:0060788	ectodermal placode formation	1/319	12/18722	0.186401624069788	0.334773733748755	CTNNB1	1
GO:0061307	cardiac neural crest cell differentiation involved in heart development	1/319	12/18722	0.186401624069788	0.334773733748755	HES1	1
GO:0061308	cardiac neural crest cell development involved in heart development	1/319	12/18722	0.186401624069788	0.334773733748755	HES1	1
GO:0061430	bone trabecula morphogenesis	1/319	12/18722	0.186401624069788	0.334773733748755	SEMA4D	1
GO:0070943	neutrophil-mediated killing of symbiont cell	1/319	12/18722	0.186401624069788	0.334773733748755	TREM1	1
GO:0071697	ectodermal placode morphogenesis	1/319	12/18722	0.186401624069788	0.334773733748755	CTNNB1	1
GO:0072182	regulation of nephron tubule epithelial cell differentiation	1/319	12/18722	0.186401624069788	0.334773733748755	CTNNB1	1
GO:0072537	fibroblast activation	1/319	12/18722	0.186401624069788	0.334773733748755	RGCC	1
GO:0072683	T cell extravasation	1/319	12/18722	0.186401624069788	0.334773733748755	ICAM1	1
GO:0090557	establishment of endothelial intestinal barrier	1/319	12/18722	0.186401624069788	0.334773733748755	ICAM1	1
GO:0090677	reversible differentiation	1/319	12/18722	0.186401624069788	0.334773733748755	SOD2	1
GO:0097152	mesenchymal cell apoptotic process	1/319	12/18722	0.186401624069788	0.334773733748755	HIF1A	1
GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress	1/319	12/18722	0.186401624069788	0.334773733748755	JUN	1
GO:0150065	regulation of deacetylase activity	1/319	12/18722	0.186401624069788	0.334773733748755	VEGFA	1
GO:1901894	regulation of ATPase-coupled calcium transmembrane transporter activity	1/319	12/18722	0.186401624069788	0.334773733748755	VMP1	1
GO:1903599	positive regulation of autophagy of mitochondrion	1/319	12/18722	0.186401624069788	0.334773733748755	HIF1A	1
GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA	1/319	12/18722	0.186401624069788	0.334773733748755	DDX5	1
GO:1903909	regulation of receptor clustering	1/319	12/18722	0.186401624069788	0.334773733748755	CD81	1
GO:1904953	Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation	1/319	12/18722	0.186401624069788	0.334773733748755	CTNNB1	1
GO:1905205	positive regulation of connective tissue replacement	1/319	12/18722	0.186401624069788	0.334773733748755	PPP3CA	1
GO:2000561	regulation of CD4-positive, alpha-beta T cell proliferation	1/319	12/18722	0.186401624069788	0.334773733748755	CD81	1
GO:0048015	phosphatidylinositol-mediated signaling	5/319	178/18722	0.188069586672045	0.337621864981999	KLF4/FN1/TNF/OSM/SEMA4D	5
GO:0044772	mitotic cell cycle phase transition	10/319	424/18722	0.189093545530471	0.339311901211596	KLF4/DUSP1/CDKN1A/ID2/SYF2/TMEM14B/RGCC/RPS6/PIAS1/PPP3CA	10
GO:0050829	defense response to Gram-negative bacterium	3/319	88/18722	0.189605253486199	0.340081674119443	TREM1/HMGB2/DEFB1	3
GO:0007595	lactation	2/319	47/18722	0.190775844816987	0.340546894503965	HIF1A/VEGFA	2
GO:0010799	regulation of peptidyl-threonine phosphorylation	2/319	47/18722	0.190775844816987	0.340546894503965	DDIT4/RIPK2	2
GO:0031641	regulation of myelination	2/319	47/18722	0.190775844816987	0.340546894503965	CTNNB1/TYMP	2
GO:0035315	hair cell differentiation	2/319	47/18722	0.190775844816987	0.340546894503965	CTNNB1/HES1	2
GO:0035850	epithelial cell differentiation involved in kidney development	2/319	47/18722	0.190775844816987	0.340546894503965	CTNNB1/BASP1	2
GO:0043114	regulation of vascular permeability	2/319	47/18722	0.190775844816987	0.340546894503965	VEGFA/APOE	2
GO:0045581	negative regulation of T cell differentiation	2/319	47/18722	0.190775844816987	0.340546894503965	BCL6/HMGB1	2
GO:0045747	positive regulation of Notch signaling pathway	2/319	47/18722	0.190775844816987	0.340546894503965	ZMIZ1/HES1	2
GO:0048512	circadian behavior	2/319	47/18722	0.190775844816987	0.340546894503965	ID2/EGR1	2
GO:0050798	activated T cell proliferation	2/319	47/18722	0.190775844816987	0.340546894503965	PRNP/HMGB1	2
GO:0097028	dendritic cell differentiation	2/319	47/18722	0.190775844816987	0.340546894503965	CEBPB/HMGB1	2
GO:0007626	locomotory behavior	5/319	179/18722	0.190993720285432	0.340639993099095	NR4A2/ID2/SNCA/EGR1/APOE	5
GO:1901991	negative regulation of mitotic cell cycle phase transition	5/319	179/18722	0.190993720285432	0.340639993099095	KLF4/DUSP1/CDKN1A/SYF2/RGCC	5
GO:0098657	import into cell	6/319	227/18722	0.192022630532359	0.342326554257818	ATP1B3/IRS2/PRNP/SNCA/SLC2A3/THBS1	6
GO:0002715	regulation of natural killer cell mediated immunity	2/319	48/18722	0.196970655664179	0.348865795841244	SERPINB9/HLA-A	2
GO:0042149	cellular response to glucose starvation	2/319	48/18722	0.196970655664179	0.348865795841244	HNRNPA1/PMAIP1	2
GO:0043303	mast cell degranulation	2/319	48/18722	0.196970655664179	0.348865795841244	HMOX1/NR4A3	2
GO:0090311	regulation of protein deacetylation	2/319	48/18722	0.196970655664179	0.348865795841244	VEGFA/BCL6	2
GO:0032392	DNA geometric change	3/319	90/18722	0.198278238547845	0.348865795841244	HMGB2/CHD1/HMGB1	3
GO:0034644	cellular response to UV	3/319	90/18722	0.198278238547845	0.348865795841244	CDKN1A/NPM1/PTGS2	3
GO:0046849	bone remodeling	3/319	90/18722	0.198278238547845	0.348865795841244	TNFAIP3/CTNNB1/SPP1	3
GO:0048017	inositol lipid-mediated signaling	5/319	182/18722	0.199862102028564	0.348865795841244	KLF4/FN1/TNF/OSM/SEMA4D	5
GO:0001682	tRNA 5'-leader removal	1/319	13/18722	0.200273237213655	0.348865795841244	SSB	1
GO:0001833	inner cell mass cell proliferation	1/319	13/18722	0.200273237213655	0.348865795841244	SBDS	1
GO:0002551	mast cell chemotaxis	1/319	13/18722	0.200273237213655	0.348865795841244	VEGFA	1
GO:0002638	negative regulation of immunoglobulin production	1/319	13/18722	0.200273237213655	0.348865795841244	BCL6	1
GO:0003334	keratinocyte development	1/319	13/18722	0.200273237213655	0.348865795841244	FOSL2	1
GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis	1/319	13/18722	0.200273237213655	0.348865795841244	CTNNB1	1
GO:0006000	fructose metabolic process	1/319	13/18722	0.200273237213655	0.348865795841244	PFKFB3	1
GO:0006983	ER overload response	1/319	13/18722	0.200273237213655	0.348865795841244	PPP1R15B	1
GO:0007567	parturition	1/319	13/18722	0.200273237213655	0.348865795841244	MAFF	1
GO:0008298	intracellular mRNA localization	1/319	13/18722	0.200273237213655	0.348865795841244	ZFP36	1
GO:0010745	negative regulation of macrophage derived foam cell differentiation	1/319	13/18722	0.200273237213655	0.348865795841244	NFKBIA	1
GO:0010755	regulation of plasminogen activation	1/319	13/18722	0.200273237213655	0.348865795841244	THBS1	1
GO:0014745	negative regulation of muscle adaptation	1/319	13/18722	0.200273237213655	0.348865795841244	KLF4	1
GO:0016322	neuron remodeling	1/319	13/18722	0.200273237213655	0.348865795841244	C3	1
GO:0021819	layer formation in cerebral cortex	1/319	13/18722	0.200273237213655	0.348865795841244	CTNNB1	1
GO:0021859	pyramidal neuron differentiation	1/319	13/18722	0.200273237213655	0.348865795841244	ZMIZ1	1
GO:0021984	adenohypophysis development	1/319	13/18722	0.200273237213655	0.348865795841244	HES1	1
GO:0030836	positive regulation of actin filament depolymerization	1/319	13/18722	0.200273237213655	0.348865795841244	PLEK	1
GO:0032905	transforming growth factor beta1 production	1/319	13/18722	0.200273237213655	0.348865795841244	THBS1	1
GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter	1/319	13/18722	0.200273237213655	0.348865795841244	CTNNB1	1
GO:0033262	regulation of nuclear cell cycle DNA replication	1/319	13/18722	0.200273237213655	0.348865795841244	BCL6	1
GO:0034112	positive regulation of homotypic cell-cell adhesion	1/319	13/18722	0.200273237213655	0.348865795841244	PLAUR	1
GO:0034144	negative regulation of toll-like receptor 4 signaling pathway	1/319	13/18722	0.200273237213655	0.348865795841244	TNFAIP3	1
GO:0042362	fat-soluble vitamin biosynthetic process	1/319	13/18722	0.200273237213655	0.348865795841244	TNF	1
GO:0042492	gamma-delta T cell differentiation	1/319	13/18722	0.200273237213655	0.348865795841244	NCKAP1L	1
GO:0042769	DNA damage response, detection of DNA damage	1/319	13/18722	0.200273237213655	0.348865795841244	DNAJA1	1
GO:0044794	positive regulation by host of viral process	1/319	13/18722	0.200273237213655	0.348865795841244	APOE	1
GO:0048266	behavioral response to pain	1/319	13/18722	0.200273237213655	0.348865795841244	THBS1	1
GO:0048820	hair follicle maturation	1/319	13/18722	0.200273237213655	0.348865795841244	CTNNB1	1
GO:0051709	regulation of killing of cells of other organism	1/319	13/18722	0.200273237213655	0.348865795841244	SERPINB9	1
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	1/319	13/18722	0.200273237213655	0.348865795841244	HNRNPU	1
GO:0060707	trophoblast giant cell differentiation	1/319	13/18722	0.200273237213655	0.348865795841244	SOCS3	1
GO:0071696	ectodermal placode development	1/319	13/18722	0.200273237213655	0.348865795841244	CTNNB1	1
GO:0071801	regulation of podosome assembly	1/319	13/18722	0.200273237213655	0.348865795841244	TNF	1
GO:0072578	neurotransmitter-gated ion channel clustering	1/319	13/18722	0.200273237213655	0.348865795841244	APOE	1
GO:0106070	regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway	1/319	13/18722	0.200273237213655	0.348865795841244	PDE4B	1
GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding	1/319	13/18722	0.200273237213655	0.348865795841244	TMSB4X	1
GO:1903977	positive regulation of glial cell migration	1/319	13/18722	0.200273237213655	0.348865795841244	CCL3	1
GO:1904995	negative regulation of leukocyte adhesion to vascular endothelial cell	1/319	13/18722	0.200273237213655	0.348865795841244	KLF4	1
GO:1905203	regulation of connective tissue replacement	1/319	13/18722	0.200273237213655	0.348865795841244	PPP3CA	1
GO:1905244	regulation of modification of synaptic structure	1/319	13/18722	0.200273237213655	0.348865795841244	CHMP2B	1
GO:1905907	negative regulation of amyloid fibril formation	1/319	13/18722	0.200273237213655	0.348865795841244	APOE	1
GO:1905939	regulation of gonad development	1/319	13/18722	0.200273237213655	0.348865795841244	RETN	1
GO:1990403	embryonic brain development	1/319	13/18722	0.200273237213655	0.348865795841244	CTNNB1	1
GO:2000318	positive regulation of T-helper 17 type immune response	1/319	13/18722	0.200273237213655	0.348865795841244	NFKBIZ	1
GO:2001023	regulation of response to drug	1/319	13/18722	0.200273237213655	0.348865795841244	ADIRF	1
GO:0072073	kidney epithelium development	4/319	136/18722	0.202438444563698	0.350972088570028	VEGFA/CTNNB1/BASP1/HES1	4
GO:0019935	cyclic-nucleotide-mediated signaling	3/319	91/18722	0.202650328012732	0.350972088570028	APOE/DEFB1/THBS1	3
GO:0060191	regulation of lipase activity	3/319	91/18722	0.202650328012732	0.350972088570028	SNCA/C5AR1/APOC1	3
GO:0072080	nephron tubule development	3/319	91/18722	0.202650328012732	0.350972088570028	VEGFA/CTNNB1/HES1	3
GO:0002204	somatic recombination of immunoglobulin genes involved in immune response	2/319	49/18722	0.203189873703884	0.350972088570028	BCL6/STAT6	2
GO:0002208	somatic diversification of immunoglobulins involved in immune response	2/319	49/18722	0.203189873703884	0.350972088570028	BCL6/STAT6	2
GO:0002279	mast cell activation involved in immune response	2/319	49/18722	0.203189873703884	0.350972088570028	HMOX1/NR4A3	2
GO:0006692	prostanoid metabolic process	2/319	49/18722	0.203189873703884	0.350972088570028	IL1B/PTGS2	2
GO:0006693	prostaglandin metabolic process	2/319	49/18722	0.203189873703884	0.350972088570028	IL1B/PTGS2	2
GO:0007622	rhythmic behavior	2/319	49/18722	0.203189873703884	0.350972088570028	ID2/EGR1	2
GO:0009994	oocyte differentiation	2/319	49/18722	0.203189873703884	0.350972088570028	CTNNB1/EREG	2
GO:0018198	peptidyl-cysteine modification	2/319	49/18722	0.203189873703884	0.350972088570028	PRDX3/S100A8	2
GO:0030195	negative regulation of blood coagulation	2/319	49/18722	0.203189873703884	0.350972088570028	APOE/THBS1	2
GO:0032692	negative regulation of interleukin-1 production	2/319	49/18722	0.203189873703884	0.350972088570028	TNFAIP3/NLRP3	2
GO:0034332	adherens junction organization	2/319	49/18722	0.203189873703884	0.350972088570028	VEGFA/CTNNB1	2
GO:0045190	isotype switching	2/319	49/18722	0.203189873703884	0.350972088570028	BCL6/STAT6	2
GO:0048168	regulation of neuronal synaptic plasticity	2/319	49/18722	0.203189873703884	0.350972088570028	SNCA/APOE	2
GO:0050832	defense response to fungus	2/319	49/18722	0.203189873703884	0.350972088570028	COTL1/S100A8	2
GO:0070169	positive regulation of biomineral tissue development	2/319	49/18722	0.203189873703884	0.350972088570028	CEBPB/ISG15	2
GO:1990928	response to amino acid starvation	2/319	49/18722	0.203189873703884	0.350972088570028	ATF3/CDKN1A	2
GO:0006470	protein dephosphorylation	7/319	281/18722	0.20473805034397	0.353497742530055	PPP1R15A/DUSP1/PPP1R15B/TNF/HSP90AB1/PPP3CA/NCKAP1L	7
GO:0045471	response to ethanol	4/319	137/18722	0.205959713218547	0.355457758623614	ICAM1/SOD2/NLRP3/S100A8	4
GO:0035249	synaptic transmission, glutamatergic	3/319	92/18722	0.207044845358775	0.357030771505841	TNF/PTGS2/DGKZ	3
GO:0070509	calcium ion import	3/319	92/18722	0.207044845358775	0.357030771505841	CCL3/CTNNB1/PRNP	3
GO:0007160	cell-matrix adhesion	6/319	233/18722	0.207795678205251	0.358175275933663	FN1/VEGFA/CTNNB1/BCL6/LIMS1/THBS1	6
GO:1990778	protein localization to cell periphery	8/319	333/18722	0.209427018190748	0.359517659828003	ATP1B3/TNF/MYADM/PRNP/RILPL2/CD81/VAMP5/GBP1	8
GO:0007632	visual behavior	2/319	50/18722	0.20943087937886	0.359517659828003	HIF1A/PIAS1	2
GO:0030490	maturation of SSU-rRNA	2/319	50/18722	0.20943087937886	0.359517659828003	LSM6/RPS28	2
GO:0060337	type I interferon signaling pathway	2/319	50/18722	0.20943087937886	0.359517659828003	HSP90AB1/ISG15	2
GO:0060425	lung morphogenesis	2/319	50/18722	0.20943087937886	0.359517659828003	TNF/CTNNB1	2
GO:0071825	protein-lipid complex subunit organization	2/319	50/18722	0.20943087937886	0.359517659828003	APOE/APOC1	2
GO:0110151	positive regulation of biomineralization	2/319	50/18722	0.20943087937886	0.359517659828003	CEBPB/ISG15	2
GO:1900047	negative regulation of hemostasis	2/319	50/18722	0.20943087937886	0.359517659828003	APOE/THBS1	2
GO:1903747	regulation of establishment of protein localization to mitochondrion	2/319	50/18722	0.20943087937886	0.359517659828003	BNIP3L/DNAJA1	2
GO:0008217	regulation of blood pressure	5/319	186/18722	0.211899708110978	0.359517659828003	SGK1/SOD2/ID2/PTGS2/HMOX1	5
GO:0001711	endodermal cell fate commitment	1/319	14/18722	0.21390907223043	0.359517659828003	CTNNB1	1
GO:0001771	immunological synapse formation	1/319	14/18722	0.21390907223043	0.359517659828003	CD81	1
GO:0001921	positive regulation of receptor recycling	1/319	14/18722	0.21390907223043	0.359517659828003	SNCA	1
GO:0002864	regulation of acute inflammatory response to antigenic stimulus	1/319	14/18722	0.21390907223043	0.359517659828003	C3	1
GO:0009159	deoxyribonucleoside monophosphate catabolic process	1/319	14/18722	0.21390907223043	0.359517659828003	TYMP	1
GO:0009214	cyclic nucleotide catabolic process	1/319	14/18722	0.21390907223043	0.359517659828003	PDE4B	1
GO:0010457	centriole-centriole cohesion	1/319	14/18722	0.21390907223043	0.359517659828003	CTNNB1	1
GO:0010838	positive regulation of keratinocyte proliferation	1/319	14/18722	0.21390907223043	0.359517659828003	AREG	1
GO:0018158	protein oxidation	1/319	14/18722	0.21390907223043	0.359517659828003	PRDX3	1
GO:0019321	pentose metabolic process	1/319	14/18722	0.21390907223043	0.359517659828003	DCXR	1
GO:0030007	cellular potassium ion homeostasis	1/319	14/18722	0.21390907223043	0.359517659828003	ATP1B3	1
GO:0030213	hyaluronan biosynthetic process	1/319	14/18722	0.21390907223043	0.359517659828003	IL1B	1
GO:0032688	negative regulation of interferon-beta production	1/319	14/18722	0.21390907223043	0.359517659828003	NMI	1
GO:0035641	locomotory exploration behavior	1/319	14/18722	0.21390907223043	0.359517659828003	APOE	1
GO:0042921	glucocorticoid receptor signaling pathway	1/319	14/18722	0.21390907223043	0.359517659828003	YWHAH	1
GO:0043249	erythrocyte maturation	1/319	14/18722	0.21390907223043	0.359517659828003	KLF2	1
GO:0043374	CD8-positive, alpha-beta T cell differentiation	1/319	14/18722	0.21390907223043	0.359517659828003	NCKAP1L	1
GO:0045579	positive regulation of B cell differentiation	1/319	14/18722	0.21390907223043	0.359517659828003	NCKAP1L	1
GO:0045820	negative regulation of glycolytic process	1/319	14/18722	0.21390907223043	0.359517659828003	DDIT4	1
GO:0046325	negative regulation of glucose import	1/319	14/18722	0.21390907223043	0.359517659828003	TNF	1
GO:0048148	behavioral response to cocaine	1/319	14/18722	0.21390907223043	0.359517659828003	SNCA	1
GO:0048681	negative regulation of axon regeneration	1/319	14/18722	0.21390907223043	0.359517659828003	SPP1	1
GO:0048875	chemical homeostasis within a tissue	1/319	14/18722	0.21390907223043	0.359517659828003	VEGFA	1
GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	1/319	14/18722	0.21390907223043	0.359517659828003	CXCR4	1
GO:0051547	regulation of keratinocyte migration	1/319	14/18722	0.21390907223043	0.359517659828003	HBEGF	1
GO:0051589	negative regulation of neurotransmitter transport	1/319	14/18722	0.21390907223043	0.359517659828003	SNCA	1
GO:0051764	actin crosslink formation	1/319	14/18722	0.21390907223043	0.359517659828003	MARCKS	1
GO:0051917	regulation of fibrinolysis	1/319	14/18722	0.21390907223043	0.359517659828003	THBS1	1
GO:0051984	positive regulation of chromosome segregation	1/319	14/18722	0.21390907223043	0.359517659828003	HNRNPU	1
GO:0060081	membrane hyperpolarization	1/319	14/18722	0.21390907223043	0.359517659828003	SOD2	1
GO:0060354	negative regulation of cell adhesion molecule production	1/319	14/18722	0.21390907223043	0.359517659828003	CXCL8	1
GO:0060732	positive regulation of inositol phosphate biosynthetic process	1/319	14/18722	0.21390907223043	0.359517659828003	SNCA	1
GO:0060841	venous blood vessel development	1/319	14/18722	0.21390907223043	0.359517659828003	VEGFA	1
GO:0061709	reticulophagy	1/319	14/18722	0.21390907223043	0.359517659828003	UFC1	1
GO:0070278	extracellular matrix constituent secretion	1/319	14/18722	0.21390907223043	0.359517659828003	RGCC	1
GO:0070942	neutrophil mediated cytotoxicity	1/319	14/18722	0.21390907223043	0.359517659828003	TREM1	1
GO:0071236	cellular response to antibiotic	1/319	14/18722	0.21390907223043	0.359517659828003	RPL23	1
GO:0072160	nephron tubule epithelial cell differentiation	1/319	14/18722	0.21390907223043	0.359517659828003	CTNNB1	1
GO:0072498	embryonic skeletal joint development	1/319	14/18722	0.21390907223043	0.359517659828003	CTNNB1	1
GO:0086103	G protein-coupled receptor signaling pathway involved in heart process	1/319	14/18722	0.21390907223043	0.359517659828003	PDE4B	1
GO:0097091	synaptic vesicle clustering	1/319	14/18722	0.21390907223043	0.359517659828003	CTNNB1	1
GO:0097531	mast cell migration	1/319	14/18722	0.21390907223043	0.359517659828003	VEGFA	1
GO:1901077	regulation of relaxation of muscle	1/319	14/18722	0.21390907223043	0.359517659828003	PDE4B	1
GO:1901722	regulation of cell proliferation involved in kidney development	1/319	14/18722	0.21390907223043	0.359517659828003	EGR1	1
GO:1902036	regulation of hematopoietic stem cell differentiation	1/319	14/18722	0.21390907223043	0.359517659828003	OSM	1
GO:1902969	mitotic DNA replication	1/319	14/18722	0.21390907223043	0.359517659828003	BCL6	1
GO:1905049	negative regulation of metallopeptidase activity	1/319	14/18722	0.21390907223043	0.359517659828003	TIMP3	1
GO:1905065	positive regulation of vascular associated smooth muscle cell differentiation	1/319	14/18722	0.21390907223043	0.359517659828003	SOD2	1
GO:2001140	positive regulation of phospholipid transport	1/319	14/18722	0.21390907223043	0.359517659828003	APOE	1
GO:2001171	positive regulation of ATP biosynthetic process	1/319	14/18722	0.21390907223043	0.359517659828003	TMSB4X	1
GO:2001256	regulation of store-operated calcium entry	1/319	14/18722	0.21390907223043	0.359517659828003	SARAF	1
GO:0006636	unsaturated fatty acid biosynthetic process	2/319	51/18722	0.215691134784979	0.361234760018902	IL1B/PTGS2	2
GO:0010874	regulation of cholesterol efflux	2/319	51/18722	0.215691134784979	0.361234760018902	NFKBIA/APOE	2
GO:0021872	forebrain generation of neurons	2/319	51/18722	0.215691134784979	0.361234760018902	ZMIZ1/HES1	2
GO:0032873	negative regulation of stress-activated MAPK cascade	2/319	51/18722	0.215691134784979	0.361234760018902	DUSP1/DNAJA1	2
GO:0045661	regulation of myoblast differentiation	2/319	51/18722	0.215691134784979	0.361234760018902	TNF/BTG1	2
GO:0046850	regulation of bone remodeling	2/319	51/18722	0.215691134784979	0.361234760018902	TNFAIP3/SPP1	2
GO:0050982	detection of mechanical stimulus	2/319	51/18722	0.215691134784979	0.361234760018902	CXCR4/CTNNB1	2
GO:0070303	negative regulation of stress-activated protein kinase signaling cascade	2/319	51/18722	0.215691134784979	0.361234760018902	DUSP1/DNAJA1	2
GO:0000209	protein polyubiquitination	6/319	236/18722	0.215851120129187	0.361234760018902	TNFAIP3/GABARAP/CTNNB1/NMI/TRIM22/RNF19B	6
GO:0090068	positive regulation of cell cycle process	6/319	236/18722	0.215851120129187	0.361234760018902	IL1B/NPM1/HNRNPU/EREG/RGCC/IL1A	6
GO:0061326	renal tubule development	3/319	94/18722	0.215897301232411	0.361234760018902	VEGFA/CTNNB1/HES1	3
GO:0030308	negative regulation of cell growth	5/319	188/18722	0.218004550656347	0.364612167513524	CDKN1A/BCL6/BTG1/SEMA4D/SPP1	5
GO:0032355	response to estradiol	4/319	141/18722	0.220218045347249	0.368091238422034	DUSP1/AREG/CTNNB1/PTGS2	4
GO:0042982	amyloid precursor protein metabolic process	3/319	95/18722	0.220353329544302	0.368091238422034	TNF/PRNP/APOE	3
GO:0048709	oligodendrocyte differentiation	3/319	95/18722	0.220353329544302	0.368091238422034	CXCR4/CTNNB1/HES1	3
GO:0021545	cranial nerve development	2/319	52/18722	0.22196818166401	0.369886986145417	CTNNB1/HES1	2
GO:0030514	negative regulation of BMP signaling pathway	2/319	52/18722	0.22196818166401	0.369886986145417	SKIL/TOB1	2
GO:0031103	axon regeneration	2/319	52/18722	0.22196818166401	0.369886986145417	KLF4/SPP1	2
GO:0032206	positive regulation of telomere maintenance	2/319	52/18722	0.22196818166401	0.369886986145417	HNRNPA1/CTNNB1	2
GO:0048260	positive regulation of receptor-mediated endocytosis	2/319	52/18722	0.22196818166401	0.369886986145417	VEGFA/C3	2
GO:2000378	negative regulation of reactive oxygen species metabolic process	2/319	52/18722	0.22196818166401	0.369886986145417	HIF1A/PAGE4	2
GO:0009755	hormone-mediated signaling pathway	5/319	190/18722	0.224163591806797	0.369946260475991	YWHAH/DNAJA1/DDX5/ZMIZ1/NR4A3	5
GO:0030510	regulation of BMP signaling pathway	3/319	96/18722	0.224827965894131	0.369946260475991	SKIL/TOB1/HES1	3
GO:0071103	DNA conformation change	7/319	290/18722	0.226727293054423	0.369946260475991	ANP32B/HMGB2/NPM1/CHD1/SET/NAP1L1/HMGB1	7
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	1/319	15/18722	0.227313124291499	0.369946260475991	RPL7	1
GO:0002836	positive regulation of response to tumor cell	1/319	15/18722	0.227313124291499	0.369946260475991	HLA-DRB1	1
GO:0002839	positive regulation of immune response to tumor cell	1/319	15/18722	0.227313124291499	0.369946260475991	HLA-DRB1	1
GO:0010273	detoxification of copper ion	1/319	15/18722	0.227313124291499	0.369946260475991	MT2A	1
GO:0010752	regulation of cGMP-mediated signaling	1/319	15/18722	0.227313124291499	0.369946260475991	THBS1	1
GO:0010763	positive regulation of fibroblast migration	1/319	15/18722	0.227313124291499	0.369946260475991	THBS1	1
GO:0010889	regulation of sequestering of triglyceride	1/319	15/18722	0.227313124291499	0.369946260475991	PLIN2	1
GO:0014048	regulation of glutamate secretion	1/319	15/18722	0.227313124291499	0.369946260475991	SNCA	1
GO:0014733	regulation of skeletal muscle adaptation	1/319	15/18722	0.227313124291499	0.369946260475991	PPP3CA	1
GO:0014744	positive regulation of muscle adaptation	1/319	15/18722	0.227313124291499	0.369946260475991	PPP3CA	1
GO:0015671	oxygen transport	1/319	15/18722	0.227313124291499	0.369946260475991	HBG1	1
GO:0018216	peptidyl-arginine methylation	1/319	15/18722	0.227313124291499	0.369946260475991	PRMT9	1
GO:0023035	CD40 signaling pathway	1/319	15/18722	0.227313124291499	0.369946260475991	TNFAIP3	1
GO:0030252	growth hormone secretion	1/319	15/18722	0.227313124291499	0.369946260475991	SERP1	1
GO:0030852	regulation of granulocyte differentiation	1/319	15/18722	0.227313124291499	0.369946260475991	TRIB1	1
GO:0031958	corticosteroid receptor signaling pathway	1/319	15/18722	0.227313124291499	0.369946260475991	YWHAH	1
GO:0032310	prostaglandin secretion	1/319	15/18722	0.227313124291499	0.369946260475991	IL1B	1
GO:0032488	Cdc42 protein signal transduction	1/319	15/18722	0.227313124291499	0.369946260475991	APOE	1
GO:0032725	positive regulation of granulocyte macrophage colony-stimulating factor production	1/319	15/18722	0.227313124291499	0.369946260475991	IL1B	1
GO:0032897	negative regulation of viral transcription	1/319	15/18722	0.227313124291499	0.369946260475991	ZFP36	1
GO:0034380	high-density lipoprotein particle assembly	1/319	15/18722	0.227313124291499	0.369946260475991	APOE	1
GO:0034384	high-density lipoprotein particle clearance	1/319	15/18722	0.227313124291499	0.369946260475991	APOE	1
GO:0034638	phosphatidylcholine catabolic process	1/319	15/18722	0.227313124291499	0.369946260475991	APOC1	1
GO:0035493	SNARE complex assembly	1/319	15/18722	0.227313124291499	0.369946260475991	SNCA	1
GO:0036376	sodium ion export across plasma membrane	1/319	15/18722	0.227313124291499	0.369946260475991	ATP1B3	1
GO:0042159	lipoprotein catabolic process	1/319	15/18722	0.227313124291499	0.369946260475991	APOE	1
GO:0043508	negative regulation of JUN kinase activity	1/319	15/18722	0.227313124291499	0.369946260475991	DNAJA1	1
GO:0045346	regulation of MHC class II biosynthetic process	1/319	15/18722	0.227313124291499	0.369946260475991	PF4	1
GO:0045725	positive regulation of glycogen biosynthetic process	1/319	15/18722	0.227313124291499	0.369946260475991	IRS2	1
GO:0045986	negative regulation of smooth muscle contraction	1/319	15/18722	0.227313124291499	0.369946260475991	PTGS2	1
GO:0046007	negative regulation of activated T cell proliferation	1/319	15/18722	0.227313124291499	0.369946260475991	PRNP	1
GO:0046834	lipid phosphorylation	1/319	15/18722	0.227313124291499	0.369946260475991	DGKZ	1
GO:0051127	positive regulation of actin nucleation	1/319	15/18722	0.227313124291499	0.369946260475991	BRK1	1
GO:0051315	attachment of mitotic spindle microtubules to kinetochore	1/319	15/18722	0.227313124291499	0.369946260475991	HNRNPU	1
GO:0060253	negative regulation of glial cell proliferation	1/319	15/18722	0.227313124291499	0.369946260475991	HES1	1
GO:0070863	positive regulation of protein exit from endoplasmic reticulum	1/319	15/18722	0.227313124291499	0.369946260475991	CD81	1
GO:0070885	negative regulation of calcineurin-NFAT signaling cascade	1/319	15/18722	0.227313124291499	0.369946260475991	PRNP	1
GO:0070886	positive regulation of calcineurin-NFAT signaling cascade	1/319	15/18722	0.227313124291499	0.369946260475991	TNF	1
GO:0071380	cellular response to prostaglandin E stimulus	1/319	15/18722	0.227313124291499	0.369946260475991	PTGER4	1
GO:0071474	cellular hyperosmotic response	1/319	15/18722	0.227313124291499	0.369946260475991	YBX3	1
GO:0072075	metanephric mesenchyme development	1/319	15/18722	0.227313124291499	0.369946260475991	BASP1	1
GO:0072224	metanephric glomerulus development	1/319	15/18722	0.227313124291499	0.369946260475991	EGR1	1
GO:0099170	postsynaptic modulation of chemical synaptic transmission	1/319	15/18722	0.227313124291499	0.369946260475991	PPP3CA	1
GO:0106057	negative regulation of calcineurin-mediated signaling	1/319	15/18722	0.227313124291499	0.369946260475991	PRNP	1
GO:0106058	positive regulation of calcineurin-mediated signaling	1/319	15/18722	0.227313124291499	0.369946260475991	TNF	1
GO:0110156	methylguanosine-cap decapping	1/319	15/18722	0.227313124291499	0.369946260475991	ZFP36	1
GO:0140374	antiviral innate immune response	1/319	15/18722	0.227313124291499	0.369946260475991	IFIT1	1
GO:1901836	regulation of transcription of nucleolar large rRNA by RNA polymerase I	1/319	15/18722	0.227313124291499	0.369946260475991	NCL	1
GO:1901841	regulation of high voltage-gated calcium channel activity	1/319	15/18722	0.227313124291499	0.369946260475991	PDE4B	1
GO:1904424	regulation of GTP binding	1/319	15/18722	0.227313124291499	0.369946260475991	CCPG1	1
GO:1905288	vascular associated smooth muscle cell apoptotic process	1/319	15/18722	0.227313124291499	0.369946260475991	SOD2	1
GO:1905459	regulation of vascular associated smooth muscle cell apoptotic process	1/319	15/18722	0.227313124291499	0.369946260475991	SOD2	1
GO:1990169	stress response to copper ion	1/319	15/18722	0.227313124291499	0.369946260475991	MT2A	1
GO:2000104	negative regulation of DNA-dependent DNA replication	1/319	15/18722	0.227313124291499	0.369946260475991	BCL6	1
GO:2000345	regulation of hepatocyte proliferation	1/319	15/18722	0.227313124291499	0.369946260475991	TNFAIP3	1
GO:2001138	regulation of phospholipid transport	1/319	15/18722	0.227313124291499	0.369946260475991	APOE	1
GO:0043113	receptor clustering	2/319	53/18722	0.228259639440756	0.370899358790888	CD81/APOE	2
GO:0097479	synaptic vesicle localization	2/319	53/18722	0.228259639440756	0.370899358790888	CTNNB1/SNCA	2
GO:0099172	presynapse organization	2/319	53/18722	0.228259639440756	0.370899358790888	SNCA/C5AR1	2
GO:2000772	regulation of cellular senescence	2/319	53/18722	0.228259639440756	0.370899358790888	BCL6/YBX1	2
GO:0043255	regulation of carbohydrate biosynthetic process	3/319	97/18722	0.229320277482299	0.372475567257895	IRS2/SNCA/PLEK	3
GO:0010975	regulation of neuron projection development	10/319	445/18722	0.22962523149553	0.372823588735436	KLF4/FN1/YWHAH/VEGFA/SNX3/SKIL/SEMA4D/SPP1/APOE/PPP3CA	10
GO:0010324	membrane invagination	4/319	144/18722	0.231080021009855	0.375037491658711	SNX3/C3/THBS1/NCKAP1L	4
GO:0034470	ncRNA processing	9/319	395/18722	0.233385047744951	0.378629017868781	SBDS/LSM6/FRG1/SSB/RPS15/RPL7/RPS28/RPL5/RPS6	9
GO:0043502	regulation of muscle adaptation	3/319	98/18722	0.233829340901967	0.379200165857193	KLF4/NR4A3/PPP3CA	3
GO:0002823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	2/319	54/18722	0.234563203303617	0.379641468024082	BCL6/NCKAP1L	2
GO:0006584	catecholamine metabolic process	2/319	54/18722	0.234563203303617	0.379641468024082	NR4A2/SNCA	2
GO:0009712	catechol-containing compound metabolic process	2/319	54/18722	0.234563203303617	0.379641468024082	NR4A2/SNCA	2
GO:0043647	inositol phosphate metabolic process	2/319	54/18722	0.234563203303617	0.379641468024082	SNCA/PLEK	2
GO:0072698	protein localization to microtubule cytoskeleton	2/319	54/18722	0.234563203303617	0.379641468024082	MAPRE1/HNRNPU	2
GO:0006874	cellular calcium ion homeostasis	10/319	448/18722	0.235674654636295	0.380104420978912	CCL3/CXCR4/CCRL2/PRNP/SNCA/PTGER4/C5AR1/APOE/FPR3/HMGB1	10
GO:0010948	negative regulation of cell cycle process	7/319	294/18722	0.236754632087468	0.380104420978912	KLF4/DUSP1/CDKN1A/BCL6/SYF2/NPM1/RGCC	7
GO:0007631	feeding behavior	3/319	99/18722	0.238354242374614	0.380104420978912	FOS/NR4A3/RETN	3
GO:0010717	regulation of epithelial to mesenchymal transition	3/319	99/18722	0.238354242374614	0.380104420978912	IL1B/CTNNB1/RGCC	3
GO:0060291	long-term synaptic potentiation	3/319	99/18722	0.238354242374614	0.380104420978912	PRNP/SNCA/APOE	3
GO:0007043	cell-cell junction assembly	4/319	146/18722	0.238394141658073	0.380104420978912	IL1B/TNF/CTNNB1/TLN1	4
GO:0048813	dendrite morphogenesis	4/319	146/18722	0.238394141658073	0.380104420978912	PHACTR1/YWHAH/SEMA4D/PPP3CA	4
GO:0006869	lipid transport	9/319	398/18722	0.239870735288467	0.380104420978912	NFKBIA/IL1B/PLIN2/IRS2/SPP1/APOE/THBS1/RETN/APOC1	9
GO:0002693	positive regulation of cellular extravasation	1/319	16/18722	0.240489321081525	0.380104420978912	ICAM1	1
GO:0002713	negative regulation of B cell mediated immunity	1/319	16/18722	0.240489321081525	0.380104420978912	BCL6	1
GO:0002890	negative regulation of immunoglobulin mediated immune response	1/319	16/18722	0.240489321081525	0.380104420978912	BCL6	1
GO:0005980	glycogen catabolic process	1/319	16/18722	0.240489321081525	0.380104420978912	HMGB1	1
GO:0006206	pyrimidine nucleobase metabolic process	1/319	16/18722	0.240489321081525	0.380104420978912	TYMP	1
GO:0006266	DNA ligation	1/319	16/18722	0.240489321081525	0.380104420978912	HMGB1	1
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	1/319	16/18722	0.240489321081525	0.380104420978912	CDKN1A	1
GO:0010225	response to UV-C	1/319	16/18722	0.240489321081525	0.380104420978912	HMGN1	1
GO:0014819	regulation of skeletal muscle contraction	1/319	16/18722	0.240489321081525	0.380104420978912	NR4A1	1
GO:0017014	protein nitrosylation	1/319	16/18722	0.240489321081525	0.380104420978912	S100A8	1
GO:0018119	peptidyl-cysteine S-nitrosylation	1/319	16/18722	0.240489321081525	0.380104420978912	S100A8	1
GO:0019081	viral translation	1/319	16/18722	0.240489321081525	0.380104420978912	SSB	1
GO:0021783	preganglionic parasympathetic fiber development	1/319	16/18722	0.240489321081525	0.380104420978912	HES1	1
GO:0030575	nuclear body organization	1/319	16/18722	0.240489321081525	0.380104420978912	SERBP1	1
GO:0034138	toll-like receptor 3 signaling pathway	1/319	16/18722	0.240489321081525	0.380104420978912	TNFAIP3	1
GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter	1/319	16/18722	0.240489321081525	0.380104420978912	HNRNPU	1
GO:0034374	low-density lipoprotein particle remodeling	1/319	16/18722	0.240489321081525	0.380104420978912	APOE	1
GO:0034393	positive regulation of smooth muscle cell apoptotic process	1/319	16/18722	0.240489321081525	0.380104420978912	SOD2	1
GO:0035970	peptidyl-threonine dephosphorylation	1/319	16/18722	0.240489321081525	0.380104420978912	DUSP1	1
GO:0044849	estrous cycle	1/319	16/18722	0.240489321081525	0.380104420978912	EGR1	1
GO:0045342	MHC class II biosynthetic process	1/319	16/18722	0.240489321081525	0.380104420978912	PF4	1
GO:0045779	negative regulation of bone resorption	1/319	16/18722	0.240489321081525	0.380104420978912	TNFAIP3	1
GO:0048385	regulation of retinoic acid receptor signaling pathway	1/319	16/18722	0.240489321081525	0.380104420978912	KLF2	1
GO:0048557	embryonic digestive tract morphogenesis	1/319	16/18722	0.240489321081525	0.380104420978912	ID2	1
GO:0050862	positive regulation of T cell receptor signaling pathway	1/319	16/18722	0.240489321081525	0.380104420978912	CD81	1
GO:0050965	detection of temperature stimulus involved in sensory perception of pain	1/319	16/18722	0.240489321081525	0.380104420978912	CXCR4	1
GO:0051969	regulation of transmission of nerve impulse	1/319	16/18722	0.240489321081525	0.380104420978912	TYMP	1
GO:0055089	fatty acid homeostasis	1/319	16/18722	0.240489321081525	0.380104420978912	APOE	1
GO:0060330	regulation of response to interferon-gamma	1/319	16/18722	0.240489321081525	0.380104420978912	HSP90AB1	1
GO:0060334	regulation of interferon-gamma-mediated signaling pathway	1/319	16/18722	0.240489321081525	0.380104420978912	HSP90AB1	1
GO:0060572	morphogenesis of an epithelial bud	1/319	16/18722	0.240489321081525	0.380104420978912	CTNNB1	1
GO:0061548	ganglion development	1/319	16/18722	0.240489321081525	0.380104420978912	CTNNB1	1
GO:0070242	thymocyte apoptotic process	1/319	16/18722	0.240489321081525	0.380104420978912	HIF1A	1
GO:0070571	negative regulation of neuron projection regeneration	1/319	16/18722	0.240489321081525	0.380104420978912	SPP1	1
GO:0071361	cellular response to ethanol	1/319	16/18722	0.240489321081525	0.380104420978912	SOD2	1
GO:0071391	cellular response to estrogen stimulus	1/319	16/18722	0.240489321081525	0.380104420978912	SERPINB9	1
GO:0072109	glomerular mesangium development	1/319	16/18722	0.240489321081525	0.380104420978912	EGR1	1
GO:0072283	metanephric renal vesicle morphogenesis	1/319	16/18722	0.240489321081525	0.380104420978912	CTNNB1	1
GO:0090231	regulation of spindle checkpoint	1/319	16/18722	0.240489321081525	0.380104420978912	DUSP1	1
GO:0090266	regulation of mitotic cell cycle spindle assembly checkpoint	1/319	16/18722	0.240489321081525	0.380104420978912	DUSP1	1
GO:0097202	activation of cysteine-type endopeptidase activity	1/319	16/18722	0.240489321081525	0.380104420978912	RIPK2	1
GO:0099010	modification of postsynaptic structure	1/319	16/18722	0.240489321081525	0.380104420978912	CHMP2B	1
GO:0099116	tRNA 5'-end processing	1/319	16/18722	0.240489321081525	0.380104420978912	SSB	1
GO:1901163	regulation of trophoblast cell migration	1/319	16/18722	0.240489321081525	0.380104420978912	VEGFA	1
GO:1901201	regulation of extracellular matrix assembly	1/319	16/18722	0.240489321081525	0.380104420978912	RGCC	1
GO:1902570	protein localization to nucleolus	1/319	16/18722	0.240489321081525	0.380104420978912	NPM1	1
GO:1903504	regulation of mitotic spindle checkpoint	1/319	16/18722	0.240489321081525	0.380104420978912	DUSP1	1
GO:1904683	regulation of metalloendopeptidase activity	1/319	16/18722	0.240489321081525	0.380104420978912	TIMP3	1
GO:1904862	inhibitory synapse assembly	1/319	16/18722	0.240489321081525	0.380104420978912	SEMA4D	1
GO:1905906	regulation of amyloid fibril formation	1/319	16/18722	0.240489321081525	0.380104420978912	APOE	1
GO:2000765	regulation of cytoplasmic translation	1/319	16/18722	0.240489321081525	0.380104420978912	YBX3	1
GO:2001044	regulation of integrin-mediated signaling pathway	1/319	16/18722	0.240489321081525	0.380104420978912	LIMS1	1
GO:2001267	regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	1/319	16/18722	0.240489321081525	0.380104420978912	PLAUR	1
GO:0008333	endosome to lysosome transport	2/319	55/18722	0.240876642327673	0.38027798640901	CHMP2B/CHMP5	2
GO:0031113	regulation of microtubule polymerization	2/319	55/18722	0.240876642327673	0.38027798640901	MAPRE1/SNCA	2
GO:0042220	response to cocaine	2/319	55/18722	0.240876642327673	0.38027798640901	SNCA/HSP90AB1	2
GO:0006641	triglyceride metabolic process	3/319	100/18722	0.24289407797017	0.383168670197763	APOE/C3/APOC1	3
GO:0061640	cytoskeleton-dependent cytokinesis	3/319	100/18722	0.24289407797017	0.383168670197763	CHMP1B/CHMP2B/CHMP5	3
GO:0003007	heart morphogenesis	6/319	246/18722	0.243434034138935	0.383873154716211	HIF1A/VEGFA/PIM1/CTNNB1/ZMIZ1/HES1	6
GO:0003012	muscle system process	10/319	452/18722	0.24383212083518	0.384353469614044	KLF4/IL1B/CXCR4/NR4A1/PDE4B/PTGS2/HMOX1/TPM3/NR4A3/PPP3CA	10
GO:0010212	response to ionizing radiation	4/319	148/18722	0.245761991760081	0.387247047959255	ICAM1/CDKN1A/GRB2/EGR1	4
GO:0000288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	2/319	56/18722	0.247197797639412	0.388170414856999	ZFP36/TOB1	2
GO:0001658	branching involved in ureteric bud morphogenesis	2/319	56/18722	0.247197797639412	0.388170414856999	VEGFA/CTNNB1	2
GO:0002886	regulation of myeloid leukocyte mediated immunity	2/319	56/18722	0.247197797639412	0.388170414856999	HMOX1/C3	2
GO:0010332	response to gamma radiation	2/319	56/18722	0.247197797639412	0.388170414856999	CDKN1A/EGR1	2
GO:0031529	ruffle organization	2/319	56/18722	0.247197797639412	0.388170414856999	ICAM1/PLEK	2
GO:0042733	embryonic digit morphogenesis	2/319	56/18722	0.247197797639412	0.388170414856999	CTNNB1/TMEM107	2
GO:0046456	icosanoid biosynthetic process	2/319	56/18722	0.247197797639412	0.388170414856999	IL1B/PTGS2	2
GO:0055078	sodium ion homeostasis	2/319	56/18722	0.247197797639412	0.388170414856999	ATP1B3/IL1A	2
GO:1904645	response to amyloid-beta	2/319	56/18722	0.247197797639412	0.388170414856999	ICAM1/PRNP	2
GO:0048167	regulation of synaptic plasticity	5/319	198/18722	0.249293947351416	0.391312492387045	YWHAH/PRNP/SNCA/PTGS2/APOE	5
GO:0009411	response to UV	4/319	149/18722	0.24946486437876	0.391319814986624	CDKN1A/NPM1/PTGS2/HMGN1	4
GO:1901990	regulation of mitotic cell cycle phase transition	7/319	299/18722	0.249488989316454	0.391319814986624	KLF4/DUSP1/CDKN1A/ID2/SYF2/TMEM14B/RGCC	7
GO:1902749	regulation of cell cycle G2/M phase transition	3/319	102/18722	0.252014986268898	0.391377976319177	CDKN1A/SYF2/NPM1	3
GO:0016050	vesicle organization	7/319	300/18722	0.25206104672343	0.391377976319177	CHMP1B/CHMP2B/STX11/CHMP5/SRGN/SNX3/SNCA	7
GO:0001710	mesodermal cell fate commitment	1/319	17/18722	0.253441523934887	0.391377976319177	KLF4	1
GO:0001829	trophectodermal cell differentiation	1/319	17/18722	0.253441523934887	0.391377976319177	JUNB	1
GO:0007096	regulation of exit from mitosis	1/319	17/18722	0.253441523934887	0.391377976319177	RGCC	1
GO:0007351	tripartite regional subdivision	1/319	17/18722	0.253441523934887	0.391377976319177	BASP1	1
GO:0008334	histone mRNA metabolic process	1/319	17/18722	0.253441523934887	0.391377976319177	SSB	1
GO:0008595	anterior/posterior axis specification, embryo	1/319	17/18722	0.253441523934887	0.391377976319177	BASP1	1
GO:0009251	glucan catabolic process	1/319	17/18722	0.253441523934887	0.391377976319177	HMGB1	1
GO:0010566	regulation of ketone biosynthetic process	1/319	17/18722	0.253441523934887	0.391377976319177	EGR1	1
GO:0010612	regulation of cardiac muscle adaptation	1/319	17/18722	0.253441523934887	0.391377976319177	PPP3CA	1
GO:0016264	gap junction assembly	1/319	17/18722	0.253441523934887	0.391377976319177	IL1B	1
GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway	1/319	17/18722	0.253441523934887	0.391377976319177	CHMP5	1
GO:0032604	granulocyte macrophage colony-stimulating factor production	1/319	17/18722	0.253441523934887	0.391377976319177	IL1B	1
GO:0032645	regulation of granulocyte macrophage colony-stimulating factor production	1/319	17/18722	0.253441523934887	0.391377976319177	IL1B	1
GO:0036166	phenotypic switching	1/319	17/18722	0.253441523934887	0.391377976319177	SOD2	1
GO:0042448	progesterone metabolic process	1/319	17/18722	0.253441523934887	0.391377976319177	EGR1	1
GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	1/319	17/18722	0.253441523934887	0.391377976319177	SOCS3	1
GO:0042772	DNA damage response, signal transduction resulting in transcription	1/319	17/18722	0.253441523934887	0.391377976319177	CDKN1A	1
GO:0042953	lipoprotein transport	1/319	17/18722	0.253441523934887	0.391377976319177	VMP1	1
GO:0045815	positive regulation of gene expression, epigenetic	1/319	17/18722	0.253441523934887	0.391377976319177	ZMIZ1	1
GO:0048521	negative regulation of behavior	1/319	17/18722	0.253441523934887	0.391377976319177	RETN	1
GO:0051580	regulation of neurotransmitter uptake	1/319	17/18722	0.253441523934887	0.391377976319177	SNCA	1
GO:0051797	regulation of hair follicle development	1/319	17/18722	0.253441523934887	0.391377976319177	TNF	1
GO:0055119	relaxation of cardiac muscle	1/319	17/18722	0.253441523934887	0.391377976319177	PDE4B	1
GO:0060977	coronary vasculature morphogenesis	1/319	17/18722	0.253441523934887	0.391377976319177	VEGFA	1
GO:0061158	3'-UTR-mediated mRNA destabilization	1/319	17/18722	0.253441523934887	0.391377976319177	ZFP36	1
GO:0061298	retina vasculature development in camera-type eye	1/319	17/18722	0.253441523934887	0.391377976319177	HIF1A	1
GO:0061450	trophoblast cell migration	1/319	17/18722	0.253441523934887	0.391377976319177	VEGFA	1
GO:0070293	renal absorption	1/319	17/18722	0.253441523934887	0.391377976319177	SGK1	1
GO:0090083	regulation of inclusion body assembly	1/319	17/18722	0.253441523934887	0.391377976319177	DNAJB6	1
GO:0090399	replicative senescence	1/319	17/18722	0.253441523934887	0.391377976319177	CDKN1A	1
GO:0090494	dopamine uptake	1/319	17/18722	0.253441523934887	0.391377976319177	SNCA	1
GO:1900363	regulation of mRNA polyadenylation	1/319	17/18722	0.253441523934887	0.391377976319177	YTHDC1	1
GO:1903242	regulation of cardiac muscle hypertrophy in response to stress	1/319	17/18722	0.253441523934887	0.391377976319177	PPP3CA	1
GO:2000696	regulation of epithelial cell differentiation involved in kidney development	1/319	17/18722	0.253441523934887	0.391377976319177	CTNNB1	1
GO:2000811	negative regulation of anoikis	1/319	17/18722	0.253441523934887	0.391377976319177	MCL1	1
GO:0006611	protein export from nucleus	2/319	57/18722	0.253524580622225	0.391377976319177	IL1B/ANP32B	2
GO:0010257	NADH dehydrogenase complex assembly	2/319	57/18722	0.253524580622225	0.391377976319177	NDUFS5/NDUFA6	2
GO:0016447	somatic recombination of immunoglobulin gene segments	2/319	57/18722	0.253524580622225	0.391377976319177	BCL6/STAT6	2
GO:0030219	megakaryocyte differentiation	2/319	57/18722	0.253524580622225	0.391377976319177	HMGB2/PF4	2
GO:0032981	mitochondrial respiratory chain complex I assembly	2/319	57/18722	0.253524580622225	0.391377976319177	NDUFS5/NDUFA6	2
GO:0019233	sensory perception of pain	3/319	103/18722	0.256594302129723	0.395819578257145	CCL3/CXCR4/PTGS2	3
GO:0050773	regulation of dendrite development	3/319	103/18722	0.256594302129723	0.395819578257145	YWHAH/SEMA4D/PPP3CA	3
GO:0048592	eye morphogenesis	4/319	151/18722	0.256906119208522	0.396003395600388	HIF1A/VEGFA/CTNNB1/HMGN1	4
GO:0048754	branching morphogenesis of an epithelial tube	4/319	151/18722	0.256906119208522	0.396003395600388	VEGFA/TNF/AREG/CTNNB1	4
GO:0009952	anterior/posterior pattern specification	5/319	201/18722	0.258900255255162	0.398927642186645	BHLHE40/CTNNB1/ETS2/BASP1/HES1	5
GO:0001954	positive regulation of cell-matrix adhesion	2/319	58/18722	0.259854971161827	0.399231967344536	VEGFA/LIMS1	2
GO:0002931	response to ischemia	2/319	58/18722	0.259854971161827	0.399231967344536	PPIF/EGR1	2
GO:0006826	iron ion transport	2/319	58/18722	0.259854971161827	0.399231967344536	SLC25A37/FTH1	2
GO:0010559	regulation of glycoprotein biosynthetic process	2/319	58/18722	0.259854971161827	0.399231967344536	HBEGF/CTNNB1	2
GO:0043506	regulation of JUN kinase activity	2/319	58/18722	0.259854971161827	0.399231967344536	TNF/DNAJA1	2
GO:0044380	protein localization to cytoskeleton	2/319	58/18722	0.259854971161827	0.399231967344536	MAPRE1/HNRNPU	2
GO:0055074	calcium ion homeostasis	10/319	460/18722	0.260443077484345	0.399231967344536	CCL3/CXCR4/CCRL2/PRNP/SNCA/PTGER4/C5AR1/APOE/FPR3/HMGB1	10
GO:0090257	regulation of muscle system process	6/319	252/18722	0.260461996604496	0.399231967344536	KLF4/NR4A1/PDE4B/PTGS2/NR4A3/PPP3CA	6
GO:0032006	regulation of TOR signaling	3/319	104/18722	0.261185038769272	0.399231967344536	DDIT4/HIF1A/NCKAP1L	3
GO:1901890	positive regulation of cell junction assembly	3/319	104/18722	0.261185038769272	0.399231967344536	VEGFA/LIMS1/SEMA4D	3
GO:1903076	regulation of protein localization to plasma membrane	3/319	104/18722	0.261185038769272	0.399231967344536	TNF/PRNP/GBP1	3
GO:0016051	carbohydrate biosynthetic process	5/319	202/18722	0.26212207225122	0.399231967344536	ATF3/PGK1/IRS2/SNCA/PLEK	5
GO:0032869	cellular response to insulin stimulus	5/319	203/18722	0.26535324816983	0.399231967344536	SOCS3/IL1B/SRSF5/GRB2/IRS2	5
GO:0032231	regulation of actin filament bundle assembly	3/319	105/18722	0.265786344297768	0.399231967344536	PTGER4/PLEK/RGCC	3
GO:0062207	regulation of pattern recognition receptor signaling pathway	3/319	105/18722	0.265786344297768	0.399231967344536	TNFAIP3/BIRC3/HMGB1	3
GO:0001956	positive regulation of neurotransmitter secretion	1/319	18/18722	0.266173528953052	0.399231967344536	SNCA	1
GO:0002076	osteoblast development	1/319	18/18722	0.266173528953052	0.399231967344536	JUND	1
GO:0002295	T-helper cell lineage commitment	1/319	18/18722	0.266173528953052	0.399231967344536	STAT6	1
GO:0002643	regulation of tolerance induction	1/319	18/18722	0.266173528953052	0.399231967344536	HMGB1	1
GO:0002923	regulation of humoral immune response mediated by circulating immunoglobulin	1/319	18/18722	0.266173528953052	0.399231967344536	TNF	1
GO:0006337	nucleosome disassembly	1/319	18/18722	0.266173528953052	0.399231967344536	SET	1
GO:0006415	translational termination	1/319	18/18722	0.266173528953052	0.399231967344536	ETF1	1
GO:0006957	complement activation, alternative pathway	1/319	18/18722	0.266173528953052	0.399231967344536	C3	1
GO:0009125	nucleoside monophosphate catabolic process	1/319	18/18722	0.266173528953052	0.399231967344536	TYMP	1
GO:0010985	negative regulation of lipoprotein particle clearance	1/319	18/18722	0.266173528953052	0.399231967344536	APOC1	1
GO:0015732	prostaglandin transport	1/319	18/18722	0.266173528953052	0.399231967344536	IL1B	1
GO:0019896	axonal transport of mitochondrion	1/319	18/18722	0.266173528953052	0.399231967344536	HIF1A	1
GO:0021534	cell proliferation in hindbrain	1/319	18/18722	0.266173528953052	0.399231967344536	C5AR1	1
GO:0030889	negative regulation of B cell proliferation	1/319	18/18722	0.266173528953052	0.399231967344536	MNDA	1
GO:0032305	positive regulation of icosanoid secretion	1/319	18/18722	0.266173528953052	0.399231967344536	IL1B	1
GO:0032769	negative regulation of monooxygenase activity	1/319	18/18722	0.266173528953052	0.399231967344536	SNCA	1
GO:0032785	negative regulation of DNA-templated transcription, elongation	1/319	18/18722	0.266173528953052	0.399231967344536	HNRNPU	1
GO:0034162	toll-like receptor 9 signaling pathway	1/319	18/18722	0.266173528953052	0.399231967344536	HMGB1	1
GO:0042790	nucleolar large rRNA transcription by RNA polymerase I	1/319	18/18722	0.266173528953052	0.399231967344536	NCL	1
GO:0043116	negative regulation of vascular permeability	1/319	18/18722	0.266173528953052	0.399231967344536	VEGFA	1
GO:0043217	myelin maintenance	1/319	18/18722	0.266173528953052	0.399231967344536	CXCR4	1
GO:0044247	cellular polysaccharide catabolic process	1/319	18/18722	0.266173528953052	0.399231967344536	HMGB1	1
GO:0044872	lipoprotein localization	1/319	18/18722	0.266173528953052	0.399231967344536	VMP1	1
GO:0045623	negative regulation of T-helper cell differentiation	1/319	18/18722	0.266173528953052	0.399231967344536	BCL6	1
GO:0045653	negative regulation of megakaryocyte differentiation	1/319	18/18722	0.266173528953052	0.399231967344536	PF4	1
GO:0046851	negative regulation of bone remodeling	1/319	18/18722	0.266173528953052	0.399231967344536	TNFAIP3	1
GO:0048486	parasympathetic nervous system development	1/319	18/18722	0.266173528953052	0.399231967344536	HES1	1
GO:0048643	positive regulation of skeletal muscle tissue development	1/319	18/18722	0.266173528953052	0.399231967344536	CTNNB1	1
GO:0050665	hydrogen peroxide biosynthetic process	1/319	18/18722	0.266173528953052	0.399231967344536	SOD2	1
GO:0051447	negative regulation of meiotic cell cycle	1/319	18/18722	0.266173528953052	0.399231967344536	DUSP1	1
GO:0051895	negative regulation of focal adhesion assembly	1/319	18/18722	0.266173528953052	0.399231967344536	THBS1	1
GO:0060008	Sertoli cell differentiation	1/319	18/18722	0.266173528953052	0.399231967344536	ICAM1	1
GO:0060192	negative regulation of lipase activity	1/319	18/18722	0.266173528953052	0.399231967344536	APOC1	1
GO:0060438	trachea development	1/319	18/18722	0.266173528953052	0.399231967344536	CTNNB1	1
GO:0060602	branch elongation of an epithelium	1/319	18/18722	0.266173528953052	0.399231967344536	AREG	1
GO:0061687	detoxification of inorganic compound	1/319	18/18722	0.266173528953052	0.399231967344536	MT2A	1
GO:0071318	cellular response to ATP	1/319	18/18722	0.266173528953052	0.399231967344536	PTGS2	1
GO:0071360	cellular response to exogenous dsRNA	1/319	18/18722	0.266173528953052	0.399231967344536	IFIT1	1
GO:0071800	podosome assembly	1/319	18/18722	0.266173528953052	0.399231967344536	TNF	1
GO:0072079	nephron tubule formation	1/319	18/18722	0.266173528953052	0.399231967344536	CTNNB1	1
GO:0072234	metanephric nephron tubule development	1/319	18/18722	0.266173528953052	0.399231967344536	HES1	1
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis	1/319	18/18722	0.266173528953052	0.399231967344536	VEGFA	1
GO:0090493	catecholamine uptake	1/319	18/18722	0.266173528953052	0.399231967344536	SNCA	1
GO:0097094	craniofacial suture morphogenesis	1/319	18/18722	0.266173528953052	0.399231967344536	TMEM107	1
GO:0110154	RNA decapping	1/319	18/18722	0.266173528953052	0.399231967344536	ZFP36	1
GO:0150118	negative regulation of cell-substrate junction organization	1/319	18/18722	0.266173528953052	0.399231967344536	THBS1	1
GO:1901317	regulation of flagellated sperm motility	1/319	18/18722	0.266173528953052	0.399231967344536	DEFB1	1
GO:1902074	response to salt	1/319	18/18722	0.266173528953052	0.399231967344536	HNRNPA1	1
GO:1902170	cellular response to reactive nitrogen species	1/319	18/18722	0.266173528953052	0.399231967344536	STAT6	1
GO:1903209	positive regulation of oxidative stress-induced cell death	1/319	18/18722	0.266173528953052	0.399231967344536	MCL1	1
GO:2000641	regulation of early endosome to late endosome transport	1/319	18/18722	0.266173528953052	0.399231967344536	SNX3	1
GO:0006406	mRNA export from nucleus	2/319	59/18722	0.266187015930764	0.399231967344536	SRSF3/YTHDC1	2
GO:0043551	regulation of phosphatidylinositol 3-kinase activity	2/319	59/18722	0.266187015930764	0.399231967344536	KLF4/SOCS3	2
GO:0046324	regulation of glucose import	2/319	59/18722	0.266187015930764	0.399231967344536	TNF/IRS2	2
GO:0048278	vesicle docking	2/319	59/18722	0.266187015930764	0.399231967344536	STX11/PLEK	2
GO:0051055	negative regulation of lipid biosynthetic process	2/319	59/18722	0.266187015930764	0.399231967344536	APOE/APOC1	2
GO:0071427	mRNA-containing ribonucleoprotein complex export from nucleus	2/319	59/18722	0.266187015930764	0.399231967344536	SRSF3/YTHDC1	2
GO:0071806	protein transmembrane transport	2/319	59/18722	0.266187015930764	0.399231967344536	MCL1/TOMM22	2
GO:0006338	chromatin remodeling	6/319	255/18722	0.269092825009045	0.40344296265944	KDM6B/ANP32B/HMGB2/NPM1/SET/NAP1L1	6
GO:0006906	vesicle fusion	3/319	106/18722	0.27039737769927	0.404808310168136	CHMP2B/STX11/SNCA	3
GO:0030038	contractile actin filament bundle assembly	3/319	106/18722	0.27039737769927	0.404808310168136	PHACTR1/PTGER4/RGCC	3
GO:0043149	stress fiber assembly	3/319	106/18722	0.27039737769927	0.404808310168136	PHACTR1/PTGER4/RGCC	3
GO:1905477	positive regulation of protein localization to membrane	3/319	106/18722	0.27039737769927	0.404808310168136	TNF/PRNP/CD81	3
GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	6/319	256/18722	0.271985692929959	0.406946929389662	SKIL/HSP90AB1/LRG1/TOB1/HES1/THBS1	6
GO:0006289	nucleotide-excision repair	2/319	60/18722	0.272518826711199	0.406946929389662	HMGN1/HMGB1	2
GO:0009620	response to fungus	2/319	60/18722	0.272518826711199	0.406946929389662	COTL1/S100A8	2
GO:0010972	negative regulation of G2/M transition of mitotic cell cycle	2/319	60/18722	0.272518826711199	0.406946929389662	CDKN1A/SYF2	2
GO:0031102	neuron projection regeneration	2/319	60/18722	0.272518826711199	0.406946929389662	KLF4/SPP1	2
GO:0042306	regulation of protein import into nucleus	2/319	60/18722	0.272518826711199	0.406946929389662	PTGS2/HSP90AB1	2
GO:0061951	establishment of protein localization to plasma membrane	2/319	60/18722	0.272518826711199	0.406946929389662	RILPL2/VAMP5	2
GO:0006275	regulation of DNA replication	3/319	107/18722	0.275017308957862	0.409702111244633	JUN/BCL6/EREG	3
GO:0031532	actin cytoskeleton reorganization	3/319	107/18722	0.275017308957862	0.409702111244633	PHACTR1/GRB2/PLEK	3
GO:0042303	molting cycle	3/319	107/18722	0.275017308957862	0.409702111244633	TNF/CTNNB1/PTGS2	3
GO:0042633	hair cycle	3/319	107/18722	0.275017308957862	0.409702111244633	TNF/CTNNB1/PTGS2	3
GO:0071868	cellular response to monoamine stimulus	3/319	107/18722	0.275017308957862	0.409702111244633	PDE4B/SNCA/NR4A3	3
GO:0071870	cellular response to catecholamine stimulus	3/319	107/18722	0.275017308957862	0.409702111244633	PDE4B/SNCA/NR4A3	3
GO:0061564	axon development	10/319	467/18722	0.275275933627254	0.409702111244633	KLF4/NR4A2/FN1/VEGFA/SKIL/SEMA4D/S100A6/HSP90AB1/SPP1/APOE	10
GO:0035051	cardiocyte differentiation	4/319	156/18722	0.275694386078263	0.409702111244633	KDM6B/VEGFA/HNRNPU/HES1	4
GO:0001696	gastric acid secretion	1/319	19/18722	0.27868906810318	0.409702111244633	SGK1	1
GO:0002888	positive regulation of myeloid leukocyte mediated immunity	1/319	19/18722	0.27868906810318	0.409702111244633	C3	1
GO:0003085	negative regulation of systemic arterial blood pressure	1/319	19/18722	0.27868906810318	0.409702111244633	SOD2	1
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	1/319	19/18722	0.27868906810318	0.409702111244633	CDKN1A	1
GO:0007039	protein catabolic process in the vacuole	1/319	19/18722	0.27868906810318	0.409702111244633	CD81	1
GO:0007213	G protein-coupled acetylcholine receptor signaling pathway	1/319	19/18722	0.27868906810318	0.409702111244633	RGS10	1
GO:0009223	pyrimidine deoxyribonucleotide catabolic process	1/319	19/18722	0.27868906810318	0.409702111244633	TYMP	1
GO:0010544	negative regulation of platelet activation	1/319	19/18722	0.27868906810318	0.409702111244633	APOE	1
GO:0010744	positive regulation of macrophage derived foam cell differentiation	1/319	19/18722	0.27868906810318	0.409702111244633	PF4	1
GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling	1/319	19/18722	0.27868906810318	0.409702111244633	KLF4	1
GO:0016082	synaptic vesicle priming	1/319	19/18722	0.27868906810318	0.409702111244633	SNCA	1
GO:0030011	maintenance of cell polarity	1/319	19/18722	0.27868906810318	0.409702111244633	NCKAP1L	1
GO:0031290	retinal ganglion cell axon guidance	1/319	19/18722	0.27868906810318	0.409702111244633	VEGFA	1
GO:0032695	negative regulation of interleukin-12 production	1/319	19/18722	0.27868906810318	0.409702111244633	THBS1	1
GO:0035313	wound healing, spreading of epidermal cells	1/319	19/18722	0.27868906810318	0.409702111244633	HBEGF	1
GO:0043652	engulfment of apoptotic cell	1/319	19/18722	0.27868906810318	0.409702111244633	THBS1	1
GO:0044003	modulation by symbiont of host process	1/319	19/18722	0.27868906810318	0.409702111244633	SERPINB9	1
GO:0044320	cellular response to leptin stimulus	1/319	19/18722	0.27868906810318	0.409702111244633	NR4A3	1
GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate	1/319	19/18722	0.27868906810318	0.409702111244633	CXCL8	1
GO:0045780	positive regulation of bone resorption	1/319	19/18722	0.27868906810318	0.409702111244633	SPP1	1
GO:0045821	positive regulation of glycolytic process	1/319	19/18722	0.27868906810318	0.409702111244633	HIF1A	1
GO:0046716	muscle cell cellular homeostasis	1/319	19/18722	0.27868906810318	0.409702111244633	HIF1A	1
GO:0046782	regulation of viral transcription	1/319	19/18722	0.27868906810318	0.409702111244633	ZFP36	1
GO:0050961	detection of temperature stimulus involved in sensory perception	1/319	19/18722	0.27868906810318	0.409702111244633	CXCR4	1
GO:0051546	keratinocyte migration	1/319	19/18722	0.27868906810318	0.409702111244633	HBEGF	1
GO:0051571	positive regulation of histone H3-K4 methylation	1/319	19/18722	0.27868906810318	0.409702111244633	CTNNB1	1
GO:0072074	kidney mesenchyme development	1/319	19/18722	0.27868906810318	0.409702111244633	BASP1	1
GO:0072077	renal vesicle morphogenesis	1/319	19/18722	0.27868906810318	0.409702111244633	CTNNB1	1
GO:0097501	stress response to metal ion	1/319	19/18722	0.27868906810318	0.409702111244633	MT2A	1
GO:1901881	positive regulation of protein depolymerization	1/319	19/18722	0.27868906810318	0.409702111244633	PLEK	1
GO:1903978	regulation of microglial cell activation	1/319	19/18722	0.27868906810318	0.409702111244633	CCL3	1
GO:2000319	regulation of T-helper 17 cell differentiation	1/319	19/18722	0.27868906810318	0.409702111244633	NFKBIZ	1
GO:2000831	regulation of steroid hormone secretion	1/319	19/18722	0.27868906810318	0.409702111244633	RETN	1
GO:0006900	vesicle budding from membrane	2/319	61/18722	0.278848578755165	0.409702111244633	CHMP5/SNX3	2
GO:0043954	cellular component maintenance	2/319	61/18722	0.278848578755165	0.409702111244633	PRNP/APOE	2
GO:0090342	regulation of cell aging	2/319	61/18722	0.278848578755165	0.409702111244633	BCL6/YBX1	2
GO:1905515	non-motile cilium assembly	2/319	61/18722	0.278848578755165	0.409702111244633	MAPRE1/TMEM107	2
GO:1902600	proton transmembrane transport	4/319	157/18722	0.279480047217083	0.410483199038738	TMSB4X/PPIF/COX7A2L/ATP6V1B2	4
GO:0007409	axonogenesis	9/319	418/18722	0.284607506504053	0.417864806870772	NR4A2/FN1/VEGFA/SKIL/SEMA4D/S100A6/HSP90AB1/SPP1/APOE	9
GO:0045576	mast cell activation	2/319	62/18722	0.285174509181512	0.418100002583879	HMOX1/NR4A3	2
GO:0046173	polyol biosynthetic process	2/319	62/18722	0.285174509181512	0.418100002583879	SNCA/PLEK	2
GO:1902750	negative regulation of cell cycle G2/M phase transition	2/319	62/18722	0.285174509181512	0.418100002583879	CDKN1A/SYF2	2
GO:1903078	positive regulation of protein localization to plasma membrane	2/319	62/18722	0.285174509181512	0.418100002583879	TNF/PRNP	2
GO:0032200	telomere organization	4/319	159/18722	0.287075702713852	0.420332864418923	HNRNPA1/CTNNB1/HSP90AB1/HNRNPU	4
GO:1903169	regulation of calcium ion transmembrane transport	4/319	159/18722	0.287075702713852	0.420332864418923	PDE4B/PRNP/VMP1/SNCA	4
GO:0060249	anatomical structure homeostasis	7/319	314/18722	0.288844216485616	0.420332864418923	TNFAIP3/HIF1A/VEGFA/CHMP2B/CTNNB1/PTGS2/SPP1	7
GO:0048259	regulation of receptor-mediated endocytosis	3/319	110/18722	0.288922357046557	0.420332864418923	VEGFA/C3/APOC1	3
GO:0090174	organelle membrane fusion	3/319	110/18722	0.288922357046557	0.420332864418923	CHMP2B/STX11/SNCA	3
GO:0043271	negative regulation of ion transport	4/319	160/18722	0.290884791690598	0.420332864418923	ICAM1/PPIF/SNCA/PTGS2	4
GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	1/319	20/18722	0.290991810298286	0.420332864418923	ID2	1
GO:0000272	polysaccharide catabolic process	1/319	20/18722	0.290991810298286	0.420332864418923	HMGB1	1
GO:0001832	blastocyst growth	1/319	20/18722	0.290991810298286	0.420332864418923	SBDS	1
GO:0002115	store-operated calcium entry	1/319	20/18722	0.290991810298286	0.420332864418923	SARAF	1
GO:0002577	regulation of antigen processing and presentation	1/319	20/18722	0.290991810298286	0.420332864418923	THBS1	1
GO:0006700	C21-steroid hormone biosynthetic process	1/319	20/18722	0.290991810298286	0.420332864418923	EGR1	1
GO:0006837	serotonin transport	1/319	20/18722	0.290991810298286	0.420332864418923	SNCA	1
GO:0009110	vitamin biosynthetic process	1/319	20/18722	0.290991810298286	0.420332864418923	TNF	1
GO:0009129	pyrimidine nucleoside monophosphate metabolic process	1/319	20/18722	0.290991810298286	0.420332864418923	TYMP	1
GO:0010801	negative regulation of peptidyl-threonine phosphorylation	1/319	20/18722	0.290991810298286	0.420332864418923	DDIT4	1
GO:0010893	positive regulation of steroid biosynthetic process	1/319	20/18722	0.290991810298286	0.420332864418923	TNF	1
GO:0014047	glutamate secretion	1/319	20/18722	0.290991810298286	0.420332864418923	SNCA	1
GO:0015669	gas transport	1/319	20/18722	0.290991810298286	0.420332864418923	HBG1	1
GO:0031498	chromatin disassembly	1/319	20/18722	0.290991810298286	0.420332864418923	SET	1
GO:0032793	positive regulation of CREB transcription factor activity	1/319	20/18722	0.290991810298286	0.420332864418923	VEGFA	1
GO:0033005	positive regulation of mast cell activation	1/319	20/18722	0.290991810298286	0.420332864418923	NR4A3	1
GO:0034104	negative regulation of tissue remodeling	1/319	20/18722	0.290991810298286	0.420332864418923	TNFAIP3	1
GO:0039535	regulation of RIG-I signaling pathway	1/319	20/18722	0.290991810298286	0.420332864418923	BIRC3	1
GO:0039692	single stranded viral RNA replication via double stranded DNA intermediate	1/319	20/18722	0.290991810298286	0.420332864418923	CXCL8	1
GO:0042359	vitamin D metabolic process	1/319	20/18722	0.290991810298286	0.420332864418923	TNF	1
GO:0043586	tongue development	1/319	20/18722	0.290991810298286	0.420332864418923	CTNNB1	1
GO:0043691	reverse cholesterol transport	1/319	20/18722	0.290991810298286	0.420332864418923	APOE	1
GO:0045844	positive regulation of striated muscle tissue development	1/319	20/18722	0.290991810298286	0.420332864418923	CTNNB1	1
GO:0046629	gamma-delta T cell activation	1/319	20/18722	0.290991810298286	0.420332864418923	NCKAP1L	1
GO:0048636	positive regulation of muscle organ development	1/319	20/18722	0.290991810298286	0.420332864418923	CTNNB1	1
GO:0051004	regulation of lipoprotein lipase activity	1/319	20/18722	0.290991810298286	0.420332864418923	APOC1	1
GO:0060339	negative regulation of type I interferon-mediated signaling pathway	1/319	20/18722	0.290991810298286	0.420332864418923	ISG15	1
GO:0061318	renal filtration cell differentiation	1/319	20/18722	0.290991810298286	0.420332864418923	BASP1	1
GO:0071379	cellular response to prostaglandin stimulus	1/319	20/18722	0.290991810298286	0.420332864418923	PTGER4	1
GO:0072087	renal vesicle development	1/319	20/18722	0.290991810298286	0.420332864418923	CTNNB1	1
GO:0072112	glomerular visceral epithelial cell differentiation	1/319	20/18722	0.290991810298286	0.420332864418923	BASP1	1
GO:0090201	negative regulation of release of cytochrome c from mitochondria	1/319	20/18722	0.290991810298286	0.420332864418923	PPIF	1
GO:0097150	neuronal stem cell population maintenance	1/319	20/18722	0.290991810298286	0.420332864418923	HES1	1
GO:1902004	positive regulation of amyloid-beta formation	1/319	20/18722	0.290991810298286	0.420332864418923	TNF	1
GO:1903206	negative regulation of hydrogen peroxide-induced cell death	1/319	20/18722	0.290991810298286	0.420332864418923	NR4A3	1
GO:2000678	negative regulation of transcription regulatory region DNA binding	1/319	20/18722	0.290991810298286	0.420332864418923	TMSB4X	1
GO:0032233	positive regulation of actin filament bundle assembly	2/319	63/18722	0.291494915408781	0.420763903527212	PLEK/RGCC	2
GO:1904589	regulation of protein import	2/319	63/18722	0.291494915408781	0.420763903527212	PTGS2/HSP90AB1	2
GO:0071867	response to monoamine	3/319	111/18722	0.293569803354987	0.423313034581673	PDE4B/SNCA/NR4A3	3
GO:0071869	response to catecholamine	3/319	111/18722	0.293569803354987	0.423313034581673	PDE4B/SNCA/NR4A3	3
GO:0090288	negative regulation of cellular response to growth factor stimulus	3/319	111/18722	0.293569803354987	0.423313034581673	SKIL/TOB1/THBS1	3
GO:0006457	protein folding	5/319	212/18722	0.29480597517945	0.424797533810978	DNAJB6/PPIF/DNAJA1/ERP29/HSP90AB1	5
GO:0030258	lipid modification	5/319	212/18722	0.29480597517945	0.424797533810978	IRS2/APOE/NR4A3/DGKZ/APOC1	5
GO:0030837	negative regulation of actin filament polymerization	2/319	64/18722	0.297808153623234	0.427923565028003	TMSB4X/MYADM	2
GO:0030858	positive regulation of epithelial cell differentiation	2/319	64/18722	0.297808153623234	0.427923565028003	CTNNB1/BTG1	2
GO:0045995	regulation of embryonic development	2/319	64/18722	0.297808153623234	0.427923565028003	CTNNB1/HES1	2
GO:0048857	neural nucleus development	2/319	64/18722	0.297808153623234	0.427923565028003	YWHAH/BASP1	2
GO:0050771	negative regulation of axonogenesis	2/319	64/18722	0.297808153623234	0.427923565028003	SEMA4D/SPP1	2
GO:0070542	response to fatty acid	2/319	64/18722	0.297808153623234	0.427923565028003	PTGS2/FFAR2	2
GO:1900076	regulation of cellular response to insulin stimulus	2/319	64/18722	0.297808153623234	0.427923565028003	SOCS3/IL1B	2
GO:1903018	regulation of glycoprotein metabolic process	2/319	64/18722	0.297808153623234	0.427923565028003	HBEGF/CTNNB1	2
GO:0021953	central nervous system neuron differentiation	4/319	162/18722	0.298523252365258	0.428801219592444	NR4A2/HSP90AB1/ZMIZ1/HES1	4
GO:0000002	mitochondrial genome maintenance	1/319	21/18722	0.303085362459277	0.429649629334513	TYMP	1
GO:0002689	negative regulation of leukocyte chemotaxis	1/319	21/18722	0.303085362459277	0.429649629334513	DUSP1	1
GO:0006244	pyrimidine nucleotide catabolic process	1/319	21/18722	0.303085362459277	0.429649629334513	TYMP	1
GO:0006925	inflammatory cell apoptotic process	1/319	21/18722	0.303085362459277	0.429649629334513	HCAR2	1
GO:0007063	regulation of sister chromatid cohesion	1/319	21/18722	0.303085362459277	0.429649629334513	CTNNB1	1
GO:0007252	I-kappaB phosphorylation	1/319	21/18722	0.303085362459277	0.429649629334513	TNF	1
GO:0007289	spermatid nucleus differentiation	1/319	21/18722	0.303085362459277	0.429649629334513	HMGB2	1
GO:0007350	blastoderm segmentation	1/319	21/18722	0.303085362459277	0.429649629334513	BASP1	1
GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane	1/319	21/18722	0.303085362459277	0.429649629334513	STX11	1
GO:0031998	regulation of fatty acid beta-oxidation	1/319	21/18722	0.303085362459277	0.429649629334513	IRS2	1
GO:0032303	regulation of icosanoid secretion	1/319	21/18722	0.303085362459277	0.429649629334513	IL1B	1
GO:0033630	positive regulation of cell adhesion mediated by integrin	1/319	21/18722	0.303085362459277	0.429649629334513	NCKAP1L	1
GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation	1/319	21/18722	0.303085362459277	0.429649629334513	BRK1	1
GO:0034471	ncRNA 5'-end processing	1/319	21/18722	0.303085362459277	0.429649629334513	SSB	1
GO:0035020	regulation of Rac protein signal transduction	1/319	21/18722	0.303085362459277	0.429649629334513	GABARAP	1
GO:0038083	peptidyl-tyrosine autophosphorylation	1/319	21/18722	0.303085362459277	0.429649629334513	VEGFA	1
GO:0043373	CD4-positive, alpha-beta T cell lineage commitment	1/319	21/18722	0.303085362459277	0.429649629334513	STAT6	1
GO:0043576	regulation of respiratory gaseous exchange	1/319	21/18722	0.303085362459277	0.429649629334513	NR4A2	1
GO:0044766	multi-organism transport	1/319	21/18722	0.303085362459277	0.429649629334513	IFIT1	1
GO:0045717	negative regulation of fatty acid biosynthetic process	1/319	21/18722	0.303085362459277	0.429649629334513	APOC1	1
GO:0046599	regulation of centriole replication	1/319	21/18722	0.303085362459277	0.429649629334513	NPM1	1
GO:0048485	sympathetic nervous system development	1/319	21/18722	0.303085362459277	0.429649629334513	CTNNB1	1
GO:0048714	positive regulation of oligodendrocyte differentiation	1/319	21/18722	0.303085362459277	0.429649629334513	CXCR4	1
GO:0060445	branching involved in salivary gland morphogenesis	1/319	21/18722	0.303085362459277	0.429649629334513	TNF	1
GO:0061081	positive regulation of myeloid leukocyte cytokine production involved in immune response	1/319	21/18722	0.303085362459277	0.429649629334513	NR4A3	1
GO:0072111	cell proliferation involved in kidney development	1/319	21/18722	0.303085362459277	0.429649629334513	EGR1	1
GO:0072170	metanephric tubule development	1/319	21/18722	0.303085362459277	0.429649629334513	HES1	1
GO:0072243	metanephric nephron epithelium development	1/319	21/18722	0.303085362459277	0.429649629334513	HES1	1
GO:0072311	glomerular epithelial cell differentiation	1/319	21/18722	0.303085362459277	0.429649629334513	BASP1	1
GO:0090026	positive regulation of monocyte chemotaxis	1/319	21/18722	0.303085362459277	0.429649629334513	HMGB1	1
GO:0090189	regulation of branching involved in ureteric bud morphogenesis	1/319	21/18722	0.303085362459277	0.429649629334513	VEGFA	1
GO:0099500	vesicle fusion to plasma membrane	1/319	21/18722	0.303085362459277	0.429649629334513	STX11	1
GO:0150146	cell junction disassembly	1/319	21/18722	0.303085362459277	0.429649629334513	C3	1
GO:1901863	positive regulation of muscle tissue development	1/319	21/18722	0.303085362459277	0.429649629334513	CTNNB1	1
GO:1902307	positive regulation of sodium ion transmembrane transport	1/319	21/18722	0.303085362459277	0.429649629334513	ATP1B3	1
GO:1902579	multi-organism localization	1/319	21/18722	0.303085362459277	0.429649629334513	IFIT1	1
GO:1903427	negative regulation of reactive oxygen species biosynthetic process	1/319	21/18722	0.303085362459277	0.429649629334513	PAGE4	1
GO:2001014	regulation of skeletal muscle cell differentiation	1/319	21/18722	0.303085362459277	0.429649629334513	DDX5	1
GO:0070613	regulation of protein processing	2/319	65/18722	0.304112637281329	0.430957273996395	PRNP/THBS1	2
GO:0150063	visual system development	8/319	375/18722	0.309460401762564	0.438384463006857	KLF4/HIF1A/VEGFA/CTNNB1/SKIL/HMGN1/C3/HMGB1	8
GO:0046661	male sex differentiation	4/319	165/18722	0.310025030712961	0.438968868710105	ICAM1/CTNNB1/HMGB2/YBX3	4
GO:0019229	regulation of vasoconstriction	2/319	66/18722	0.310406835645895	0.438968868710105	ICAM1/PTGS2	2
GO:0030193	regulation of blood coagulation	2/319	66/18722	0.310406835645895	0.438968868710105	APOE/THBS1	2
GO:0042446	hormone biosynthetic process	2/319	66/18722	0.310406835645895	0.438968868710105	HIF1A/EGR1	2
GO:0046626	regulation of insulin receptor signaling pathway	2/319	66/18722	0.310406835645895	0.438968868710105	SOCS3/IL1B	2
GO:0018205	peptidyl-lysine modification	8/319	376/18722	0.311971820473997	0.441030314294568	IL1B/CTNNB1/SNCA/ZMIZ1/EGR1/SET/SUMO2/PIAS1	8
GO:0002089	lens morphogenesis in camera-type eye	1/319	22/18722	0.314973270559137	0.441930073470516	CTNNB1	1
GO:0002320	lymphoid progenitor cell differentiation	1/319	22/18722	0.314973270559137	0.441930073470516	HES1	1
GO:0008211	glucocorticoid metabolic process	1/319	22/18722	0.314973270559137	0.441930073470516	YWHAH	1
GO:0010866	regulation of triglyceride biosynthetic process	1/319	22/18722	0.314973270559137	0.441930073470516	C3	1
GO:0034755	iron ion transmembrane transport	1/319	22/18722	0.314973270559137	0.441930073470516	SLC25A37	1
GO:0035024	negative regulation of Rho protein signal transduction	1/319	22/18722	0.314973270559137	0.441930073470516	BCL6	1
GO:0035561	regulation of chromatin binding	1/319	22/18722	0.314973270559137	0.441930073470516	PPP3CA	1
GO:0045540	regulation of cholesterol biosynthetic process	1/319	22/18722	0.314973270559137	0.441930073470516	APOE	1
GO:0045663	positive regulation of myoblast differentiation	1/319	22/18722	0.314973270559137	0.441930073470516	BTG1	1
GO:0046058	cAMP metabolic process	1/319	22/18722	0.314973270559137	0.441930073470516	PDE4B	1
GO:0048026	positive regulation of mRNA splicing, via spliceosome	1/319	22/18722	0.314973270559137	0.441930073470516	NCL	1
GO:0048169	regulation of long-term neuronal synaptic plasticity	1/319	22/18722	0.314973270559137	0.441930073470516	SNCA	1
GO:0051151	negative regulation of smooth muscle cell differentiation	1/319	22/18722	0.314973270559137	0.441930073470516	EREG	1
GO:0055093	response to hyperoxia	1/319	22/18722	0.314973270559137	0.441930073470516	CDKN1A	1
GO:0060444	branching involved in mammary gland duct morphogenesis	1/319	22/18722	0.314973270559137	0.441930073470516	AREG	1
GO:0071404	cellular response to low-density lipoprotein particle stimulus	1/319	22/18722	0.314973270559137	0.441930073470516	CD81	1
GO:0090280	positive regulation of calcium ion import	1/319	22/18722	0.314973270559137	0.441930073470516	CCL3	1
GO:0099563	modification of synaptic structure	1/319	22/18722	0.314973270559137	0.441930073470516	CHMP2B	1
GO:0106118	regulation of sterol biosynthetic process	1/319	22/18722	0.314973270559137	0.441930073470516	APOE	1
GO:1900543	negative regulation of purine nucleotide metabolic process	1/319	22/18722	0.314973270559137	0.441930073470516	DDIT4	1
GO:1901032	negative regulation of response to reactive oxygen species	1/319	22/18722	0.314973270559137	0.441930073470516	NR4A3	1
GO:2000193	positive regulation of fatty acid transport	1/319	22/18722	0.314973270559137	0.441930073470516	IL1B	1
GO:0009880	embryonic pattern specification	2/319	67/18722	0.316689272355318	0.443676756008492	CTNNB1/BASP1	2
GO:0010517	regulation of phospholipase activity	2/319	67/18722	0.316689272355318	0.443676756008492	SNCA/C5AR1	2
GO:0016445	somatic diversification of immunoglobulins	2/319	67/18722	0.316689272355318	0.443676756008492	BCL6/STAT6	2
GO:1903317	regulation of protein maturation	2/319	67/18722	0.316689272355318	0.443676756008492	PRNP/THBS1	2
GO:0021782	glial cell development	3/319	116/18722	0.316865715310371	0.443676756008492	TNF/C5AR1/S100A8	3
GO:0043200	response to amino acid	3/319	116/18722	0.316865715310371	0.443676756008492	ICAM1/TNF/CEBPB	3
GO:0060562	epithelial tube morphogenesis	7/319	325/18722	0.318574863227687	0.445918032934634	CXCR4/HIF1A/VEGFA/TNF/AREG/CTNNB1/HES1	7
GO:0030301	cholesterol transport	3/319	117/18722	0.321531462559594	0.449803144682521	NFKBIA/APOE/APOC1	3
GO:0099173	postsynapse organization	4/319	168/18722	0.3215693121435	0.449803144682521	CHMP2B/PRNP/SRGN/APOE	4
GO:0042391	regulation of membrane potential	9/319	434/18722	0.321915109635771	0.450133678813828	JUN/SOD2/YWHAH/ATP1B3/BNIP3L/PRDX3/PMAIP1/SNCA/PPP3CA	9
GO:0034249	negative regulation of cellular amide metabolic process	6/319	273/18722	0.322160450588733	0.450323567619953	NCL/ZFP36/PRNP/TOB1/YBX1/APOE	6
GO:0009988	cell-cell recognition	2/319	68/18722	0.322958524025019	0.450635984527014	VDAC2/CD81	2
GO:0051926	negative regulation of calcium ion transport	2/319	68/18722	0.322958524025019	0.450635984527014	ICAM1/PTGS2	2
GO:1900046	regulation of hemostasis	2/319	68/18722	0.322958524025019	0.450635984527014	APOE/THBS1	2
GO:1902305	regulation of sodium ion transmembrane transport	2/319	68/18722	0.322958524025019	0.450635984527014	YWHAH/ATP1B3	2
GO:1904888	cranial skeletal system development	2/319	68/18722	0.322958524025019	0.450635984527014	CTNNB1/TMEM107	2
GO:0048880	sensory system development	8/319	381/18722	0.324590392527945	0.450635984527014	KLF4/HIF1A/VEGFA/CTNNB1/SKIL/HMGN1/C3/HMGB1	8
GO:1903313	positive regulation of mRNA metabolic process	3/319	118/18722	0.326197728812753	0.450635984527014	NCL/ZFP36/TOB1	3
GO:0000966	RNA 5'-end processing	1/319	23/18722	0.326659020649599	0.450635984527014	SSB	1
GO:0001759	organ induction	1/319	23/18722	0.326659020649599	0.450635984527014	CTNNB1	1
GO:0002363	alpha-beta T cell lineage commitment	1/319	23/18722	0.326659020649599	0.450635984527014	STAT6	1
GO:0006929	substrate-dependent cell migration	1/319	23/18722	0.326659020649599	0.450635984527014	FN1	1
GO:0009162	deoxyribonucleoside monophosphate metabolic process	1/319	23/18722	0.326659020649599	0.450635984527014	TYMP	1
GO:0010640	regulation of platelet-derived growth factor receptor signaling pathway	1/319	23/18722	0.326659020649599	0.450635984527014	SNCA	1
GO:0018279	protein N-linked glycosylation via asparagine	1/319	23/18722	0.326659020649599	0.450635984527014	DAD1	1
GO:0019430	removal of superoxide radicals	1/319	23/18722	0.326659020649599	0.450635984527014	SOD2	1
GO:0021884	forebrain neuron development	1/319	23/18722	0.326659020649599	0.450635984527014	ZMIZ1	1
GO:0030194	positive regulation of blood coagulation	1/319	23/18722	0.326659020649599	0.450635984527014	THBS1	1
GO:0030539	male genitalia development	1/319	23/18722	0.326659020649599	0.450635984527014	CTNNB1	1
GO:0031338	regulation of vesicle fusion	1/319	23/18722	0.326659020649599	0.450635984527014	SNCA	1
GO:0032740	positive regulation of interleukin-17 production	1/319	23/18722	0.326659020649599	0.450635984527014	OSM	1
GO:0034105	positive regulation of tissue remodeling	1/319	23/18722	0.326659020649599	0.450635984527014	PPP3CA	1
GO:0034695	response to prostaglandin E	1/319	23/18722	0.326659020649599	0.450635984527014	PTGER4	1
GO:0035640	exploration behavior	1/319	23/18722	0.326659020649599	0.450635984527014	APOE	1
GO:0035929	steroid hormone secretion	1/319	23/18722	0.326659020649599	0.450635984527014	RETN	1
GO:0036303	lymph vessel morphogenesis	1/319	23/18722	0.326659020649599	0.450635984527014	VEGFA	1
GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	1/319	23/18722	0.326659020649599	0.450635984527014	STAT6	1
GO:0043931	ossification involved in bone maturation	1/319	23/18722	0.326659020649599	0.450635984527014	SEMA4D	1
GO:0045662	negative regulation of myoblast differentiation	1/319	23/18722	0.326659020649599	0.450635984527014	TNF	1
GO:0045932	negative regulation of muscle contraction	1/319	23/18722	0.326659020649599	0.450635984527014	PTGS2	1
GO:0045943	positive regulation of transcription by RNA polymerase I	1/319	23/18722	0.326659020649599	0.450635984527014	NCL	1
GO:0045980	negative regulation of nucleotide metabolic process	1/319	23/18722	0.326659020649599	0.450635984527014	DDIT4	1
GO:0051131	chaperone-mediated protein complex assembly	1/319	23/18722	0.326659020649599	0.450635984527014	HSP90AB1	1
GO:0051457	maintenance of protein location in nucleus	1/319	23/18722	0.326659020649599	0.450635984527014	HNRNPU	1
GO:0051590	positive regulation of neurotransmitter transport	1/319	23/18722	0.326659020649599	0.450635984527014	SNCA	1
GO:0060487	lung epithelial cell differentiation	1/319	23/18722	0.326659020649599	0.450635984527014	KLF2	1
GO:0071305	cellular response to vitamin D	1/319	23/18722	0.326659020649599	0.450635984527014	PIM1	1
GO:1900048	positive regulation of hemostasis	1/319	23/18722	0.326659020649599	0.450635984527014	THBS1	1
GO:2000810	regulation of bicellular tight junction assembly	1/319	23/18722	0.326659020649599	0.450635984527014	TNF	1
GO:2001169	regulation of ATP biosynthetic process	1/319	23/18722	0.326659020649599	0.450635984527014	TMSB4X	1
GO:0003143	embryonic heart tube morphogenesis	2/319	69/18722	0.32921321888057	0.453550785126684	HIF1A/HES1	2
GO:0010611	regulation of cardiac muscle hypertrophy	2/319	69/18722	0.32921321888057	0.453550785126684	NR4A3/PPP3CA	2
GO:0050805	negative regulation of synaptic transmission	2/319	69/18722	0.32921321888057	0.453550785126684	IL1B/PTGS2	2
GO:1904377	positive regulation of protein localization to cell periphery	2/319	69/18722	0.32921321888057	0.453550785126684	TNF/PRNP	2
GO:1903829	positive regulation of cellular protein localization	6/319	276/18722	0.331166891929921	0.456089478299465	TNF/PRNP/NPM1/PTGS2/HSP90AB1/CD81	6
GO:0022412	cellular process involved in reproduction in multicellular organism	8/319	384/18722	0.332206335543	0.457367798197345	CTNNB1/HMGB2/YTHDC1/ZMIZ1/EREG/DEFB1/RETN/RPS6	8
GO:0000280	nuclear division	9/319	439/18722	0.333780103253753	0.459380650979637	DUSP1/IL1B/CHMP1B/CHMP2B/CHMP5/HNRNPU/EREG/RGCC/IL1A	9
GO:0003002	regionalization	7/319	331/18722	0.335017598521014	0.459784503717503	BHLHE40/CTNNB1/ETS2/BASP1/TMEM107/HES1/C3	7
GO:0072655	establishment of protein localization to mitochondrion	3/319	120/18722	0.335529062126644	0.459784503717503	BNIP3L/TOMM22/DNAJA1	3
GO:0007219	Notch signaling pathway	4/319	172/18722	0.337008096141702	0.459784503717503	NFKBIA/BCL6/ZMIZ1/HES1	4
GO:0007281	germ cell development	6/319	278/18722	0.33718908559025	0.459784503717503	CTNNB1/HMGB2/YTHDC1/EREG/DEFB1/RPS6	6
GO:0000395	mRNA 5'-splice site recognition	1/319	24/18722	0.338146039870561	0.459784503717503	RNU11	1
GO:0001779	natural killer cell differentiation	1/319	24/18722	0.338146039870561	0.459784503717503	NFIL3	1
GO:0002021	response to dietary excess	1/319	24/18722	0.338146039870561	0.459784503717503	APOE	1
GO:0006213	pyrimidine nucleoside metabolic process	1/319	24/18722	0.338146039870561	0.459784503717503	TYMP	1
GO:0006817	phosphate ion transport	1/319	24/18722	0.338146039870561	0.459784503717503	CEBPB	1
GO:0009219	pyrimidine deoxyribonucleotide metabolic process	1/319	24/18722	0.338146039870561	0.459784503717503	TYMP	1
GO:0010226	response to lithium ion	1/319	24/18722	0.338146039870561	0.459784503717503	PTGS2	1
GO:0010288	response to lead ion	1/319	24/18722	0.338146039870561	0.459784503717503	PTGS2	1
GO:0016048	detection of temperature stimulus	1/319	24/18722	0.338146039870561	0.459784503717503	CXCR4	1
GO:0018196	peptidyl-asparagine modification	1/319	24/18722	0.338146039870561	0.459784503717503	DAD1	1
GO:0030810	positive regulation of nucleotide biosynthetic process	1/319	24/18722	0.338146039870561	0.459784503717503	TMSB4X	1
GO:0033032	regulation of myeloid cell apoptotic process	1/319	24/18722	0.338146039870561	0.459784503717503	HCAR2	1
GO:0035458	cellular response to interferon-beta	1/319	24/18722	0.338146039870561	0.459784503717503	MNDA	1
GO:0038095	Fc-epsilon receptor signaling pathway	1/319	24/18722	0.338146039870561	0.459784503717503	NR4A3	1
GO:0039531	regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	1/319	24/18722	0.338146039870561	0.459784503717503	BIRC3	1
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	1/319	24/18722	0.338146039870561	0.459784503717503	THBS1	1
GO:0044321	response to leptin	1/319	24/18722	0.338146039870561	0.459784503717503	NR4A3	1
GO:0048011	neurotrophin TRK receptor signaling pathway	1/319	24/18722	0.338146039870561	0.459784503717503	DDIT4	1
GO:0050820	positive regulation of coagulation	1/319	24/18722	0.338146039870561	0.459784503717503	THBS1	1
GO:0050855	regulation of B cell receptor signaling pathway	1/319	24/18722	0.338146039870561	0.459784503717503	CD81	1
GO:0051123	RNA polymerase II preinitiation complex assembly	1/319	24/18722	0.338146039870561	0.459784503717503	HMGB1	1
GO:0070841	inclusion body assembly	1/319	24/18722	0.338146039870561	0.459784503717503	DNAJB6	1
GO:0071294	cellular response to zinc ion	1/319	24/18722	0.338146039870561	0.459784503717503	MT2A	1
GO:0071676	negative regulation of mononuclear cell migration	1/319	24/18722	0.338146039870561	0.459784503717503	DUSP1	1
GO:0072010	glomerular epithelium development	1/319	24/18722	0.338146039870561	0.459784503717503	BASP1	1
GO:0120255	olefinic compound biosynthetic process	1/319	24/18722	0.338146039870561	0.459784503717503	EGR1	1
GO:1900373	positive regulation of purine nucleotide biosynthetic process	1/319	24/18722	0.338146039870561	0.459784503717503	TMSB4X	1
GO:1903077	negative regulation of protein localization to plasma membrane	1/319	24/18722	0.338146039870561	0.459784503717503	GBP1	1
GO:1903428	positive regulation of reactive oxygen species biosynthetic process	1/319	24/18722	0.338146039870561	0.459784503717503	SOD2	1
GO:1903861	positive regulation of dendrite extension	1/319	24/18722	0.338146039870561	0.459784503717503	CXCR4	1
GO:2000209	regulation of anoikis	1/319	24/18722	0.338146039870561	0.459784503717503	MCL1	1
GO:2000310	regulation of NMDA receptor activity	1/319	24/18722	0.338146039870561	0.459784503717503	IFNGR2	1
GO:0016485	protein processing	5/319	225/18722	0.338211709861768	0.459784503717503	PGK1/PRNP/SRGN/RIPK2/THBS1	5
GO:0002455	humoral immune response mediated by circulating immunoglobulin	3/319	121/18722	0.340192780409878	0.462019332760161	TNF/CD81/C3	3
GO:0042752	regulation of circadian rhythm	3/319	121/18722	0.340192780409878	0.462019332760161	BHLHE40/KLF10/ID2	3
GO:0043244	regulation of protein-containing complex disassembly	3/319	121/18722	0.340192780409878	0.462019332760161	TNF/ETF1/PLEK	3
GO:0008344	adult locomotory behavior	2/319	71/18722	0.341673701117028	0.463724194550051	NR4A2/SNCA	2
GO:0071230	cellular response to amino acid stimulus	2/319	71/18722	0.341673701117028	0.463724194550051	TNF/CEBPB	2
GO:0098813	nuclear chromosome segregation	6/319	281/18722	0.346245245793059	0.46848649879819	DUSP1/CHMP1B/CHMP2B/CHMP5/CTNNB1/HNRNPU	6
GO:1901987	regulation of cell cycle phase transition	8/319	390/18722	0.34752373769854	0.46848649879819	KLF4/DUSP1/CDKN1A/ID2/SYF2/NPM1/TMEM14B/RGCC	8
GO:0001707	mesoderm formation	2/319	72/18722	0.347876991127394	0.46848649879819	KLF4/KDM6B	2
GO:0002534	cytokine production involved in inflammatory response	2/319	72/18722	0.347876991127394	0.46848649879819	HIF1A/TNF	2
GO:0005977	glycogen metabolic process	2/319	72/18722	0.347876991127394	0.46848649879819	IRS2/HMGB1	2
GO:0014743	regulation of muscle hypertrophy	2/319	72/18722	0.347876991127394	0.46848649879819	NR4A3/PPP3CA	2
GO:0033045	regulation of sister chromatid segregation	2/319	72/18722	0.347876991127394	0.46848649879819	DUSP1/HNRNPU	2
GO:0033627	cell adhesion mediated by integrin	2/319	72/18722	0.347876991127394	0.46848649879819	ICAM1/NCKAP1L	2
GO:1900015	regulation of cytokine production involved in inflammatory response	2/319	72/18722	0.347876991127394	0.46848649879819	HIF1A/TNF	2
GO:1905475	regulation of protein localization to membrane	4/319	175/18722	0.348607654279609	0.46848649879819	TNF/PRNP/CD81/GBP1	4
GO:0010560	positive regulation of glycoprotein biosynthetic process	1/319	25/18722	0.349437697442563	0.46848649879819	CTNNB1	1
GO:0015012	heparan sulfate proteoglycan biosynthetic process	1/319	25/18722	0.349437697442563	0.46848649879819	CTNNB1	1
GO:0015874	norepinephrine transport	1/319	25/18722	0.349437697442563	0.46848649879819	SNCA	1
GO:0031579	membrane raft organization	1/319	25/18722	0.349437697442563	0.46848649879819	MYADM	1
GO:0032331	negative regulation of chondrocyte differentiation	1/319	25/18722	0.349437697442563	0.46848649879819	CTNNB1	1
GO:0042730	fibrinolysis	1/319	25/18722	0.349437697442563	0.46848649879819	THBS1	1
GO:0045109	intermediate filament organization	1/319	25/18722	0.349437697442563	0.46848649879819	DNAJB6	1
GO:0046339	diacylglycerol metabolic process	1/319	25/18722	0.349437697442563	0.46848649879819	DGKZ	1
GO:0046835	carbohydrate phosphorylation	1/319	25/18722	0.349437697442563	0.46848649879819	PFKFB3	1
GO:0050951	sensory perception of temperature stimulus	1/319	25/18722	0.349437697442563	0.46848649879819	CXCR4	1
GO:0051204	protein insertion into mitochondrial membrane	1/319	25/18722	0.349437697442563	0.46848649879819	TOMM22	1
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	1/319	25/18722	0.349437697442563	0.46848649879819	MED13	1
GO:0062149	detection of stimulus involved in sensory perception of pain	1/319	25/18722	0.349437697442563	0.46848649879819	CXCR4	1
GO:0071450	cellular response to oxygen radical	1/319	25/18722	0.349437697442563	0.46848649879819	SOD2	1
GO:0071451	cellular response to superoxide	1/319	25/18722	0.349437697442563	0.46848649879819	SOD2	1
GO:0072202	cell differentiation involved in metanephros development	1/319	25/18722	0.349437697442563	0.46848649879819	CTNNB1	1
GO:0072207	metanephric epithelium development	1/319	25/18722	0.349437697442563	0.46848649879819	HES1	1
GO:0098703	calcium ion import across plasma membrane	1/319	25/18722	0.349437697442563	0.46848649879819	PRNP	1
GO:1902932	positive regulation of alcohol biosynthetic process	1/319	25/18722	0.349437697442563	0.46848649879819	SNCA	1
GO:1902993	positive regulation of amyloid precursor protein catabolic process	1/319	25/18722	0.349437697442563	0.46848649879819	TNF	1
GO:1903055	positive regulation of extracellular matrix organization	1/319	25/18722	0.349437697442563	0.46848649879819	RGCC	1
GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	1/319	25/18722	0.349437697442563	0.46848649879819	THBS1	1
GO:1903959	regulation of anion transmembrane transport	1/319	25/18722	0.349437697442563	0.46848649879819	PRNP	1
GO:1904754	positive regulation of vascular associated smooth muscle cell migration	1/319	25/18722	0.349437697442563	0.46848649879819	NR4A3	1
GO:1905048	regulation of metallopeptidase activity	1/319	25/18722	0.349437697442563	0.46848649879819	TIMP3	1
GO:1905564	positive regulation of vascular endothelial cell proliferation	1/319	25/18722	0.349437697442563	0.46848649879819	HMGB1	1
GO:2000316	regulation of T-helper 17 type immune response	1/319	25/18722	0.349437697442563	0.46848649879819	NFKBIZ	1
GO:0071482	cellular response to light stimulus	3/319	123/18722	0.34951303619899	0.46848649879819	CDKN1A/NPM1/PTGS2	3
GO:0007265	Ras protein signal transduction	7/319	337/18722	0.351577520948825	0.471100126669041	JUN/CDKN1A/GABARAP/GRB2/BCL6/BRK1/APOE	7
GO:0051146	striated muscle cell differentiation	6/319	283/18722	0.352295635146583	0.471908555258261	KDM6B/VEGFA/HNRNPU/CD81/YBX1/PPP3CA	6
GO:0006073	cellular glucan metabolic process	2/319	73/18722	0.354060727059671	0.473347528111319	IRS2/HMGB1	2
GO:0009166	nucleotide catabolic process	2/319	73/18722	0.354060727059671	0.473347528111319	PDE4B/TYMP	2
GO:0032456	endocytic recycling	2/319	73/18722	0.354060727059671	0.473347528111319	SNX3/ARL4C	2
GO:0035924	cellular response to vascular endothelial growth factor stimulus	2/319	73/18722	0.354060727059671	0.473347528111319	NR4A1/VEGFA	2
GO:0044042	glucan metabolic process	2/319	73/18722	0.354060727059671	0.473347528111319	IRS2/HMGB1	2
GO:1904427	positive regulation of calcium ion transmembrane transport	2/319	73/18722	0.354060727059671	0.473347528111319	VMP1/SNCA	2
GO:0016197	endosomal transport	5/319	230/18722	0.355063182916988	0.474533402136456	CHMP1B/CHMP2B/CHMP5/SNX3/ARL4C	5
GO:0071466	cellular response to xenobiotic stimulus	4/319	177/18722	0.356344479991771	0.476091048828785	IL1B/CXCR4/PDE4B/PRNP	4
GO:0055007	cardiac muscle cell differentiation	3/319	125/18722	0.358819475381806	0.476734919104751	KDM6B/VEGFA/HNRNPU	3
GO:1904375	regulation of protein localization to cell periphery	3/319	125/18722	0.358819475381806	0.476734919104751	TNF/PRNP/GBP1	3
GO:2000027	regulation of animal organ morphogenesis	3/319	125/18722	0.358819475381806	0.476734919104751	VEGFA/TNF/CTNNB1	3
GO:0035265	organ growth	4/319	178/18722	0.360212868343949	0.476734919104751	PIM1/BASP1/YBX3/SERP1	4
GO:0006801	superoxide metabolic process	2/319	74/18722	0.360223775747912	0.476734919104751	SOD2/NCF2	2
GO:0007040	lysosome organization	2/319	74/18722	0.360223775747912	0.476734919104751	CHMP2B/CHMP5	2
GO:0048332	mesoderm morphogenesis	2/319	74/18722	0.360223775747912	0.476734919104751	KLF4/KDM6B	2
GO:0080171	lytic vacuole organization	2/319	74/18722	0.360223775747912	0.476734919104751	CHMP2B/CHMP5	2
GO:0001556	oocyte maturation	1/319	26/18722	0.360537305642586	0.476734919104751	EREG	1
GO:0002092	positive regulation of receptor internalization	1/319	26/18722	0.360537305642586	0.476734919104751	VEGFA	1
GO:0002710	negative regulation of T cell mediated immunity	1/319	26/18722	0.360537305642586	0.476734919104751	NCKAP1L	1
GO:0021952	central nervous system projection neuron axonogenesis	1/319	26/18722	0.360537305642586	0.476734919104751	NR4A2	1
GO:0032682	negative regulation of chemokine production	1/319	26/18722	0.360537305642586	0.476734919104751	KLF4	1
GO:0034643	establishment of mitochondrion localization, microtubule-mediated	1/319	26/18722	0.360537305642586	0.476734919104751	HIF1A	1
GO:0042634	regulation of hair cycle	1/319	26/18722	0.360537305642586	0.476734919104751	TNF	1
GO:0043501	skeletal muscle adaptation	1/319	26/18722	0.360537305642586	0.476734919104751	PPP3CA	1
GO:0045745	positive regulation of G protein-coupled receptor signaling pathway	1/319	26/18722	0.360537305642586	0.476734919104751	C3	1
GO:0047497	mitochondrion transport along microtubule	1/319	26/18722	0.360537305642586	0.476734919104751	HIF1A	1
GO:0048499	synaptic vesicle membrane organization	1/319	26/18722	0.360537305642586	0.476734919104751	STX11	1
GO:0048843	negative regulation of axon extension involved in axon guidance	1/319	26/18722	0.360537305642586	0.476734919104751	SEMA4D	1
GO:0050857	positive regulation of antigen receptor-mediated signaling pathway	1/319	26/18722	0.360537305642586	0.476734919104751	CD81	1
GO:0060037	pharyngeal system development	1/319	26/18722	0.360537305642586	0.476734919104751	HES1	1
GO:0060295	regulation of cilium movement involved in cell motility	1/319	26/18722	0.360537305642586	0.476734919104751	DEFB1	1
GO:0070977	bone maturation	1/319	26/18722	0.360537305642586	0.476734919104751	SEMA4D	1
GO:0071425	hematopoietic stem cell proliferation	1/319	26/18722	0.360537305642586	0.476734919104751	PIM1	1
GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway	1/319	26/18722	0.360537305642586	0.476734919104751	PDE4B	1
GO:1902019	regulation of cilium-dependent cell motility	1/319	26/18722	0.360537305642586	0.476734919104751	DEFB1	1
GO:1902186	regulation of viral release from host cell	1/319	26/18722	0.360537305642586	0.476734919104751	CHMP2B	1
GO:1902656	calcium ion import into cytosol	1/319	26/18722	0.360537305642586	0.476734919104751	PRNP	1
GO:1904376	negative regulation of protein localization to cell periphery	1/319	26/18722	0.360537305642586	0.476734919104751	GBP1	1
GO:1905063	regulation of vascular associated smooth muscle cell differentiation	1/319	26/18722	0.360537305642586	0.476734919104751	SOD2	1
GO:2000108	positive regulation of leukocyte apoptotic process	1/319	26/18722	0.360537305642586	0.476734919104751	HCAR2	1
GO:0006094	gluconeogenesis	2/319	75/18722	0.366365048062771	0.483973879365698	ATF3/PGK1	2
GO:0008088	axo-dendritic transport	2/319	75/18722	0.366365048062771	0.483973879365698	HIF1A/HNRNPU	2
GO:2001259	positive regulation of cation channel activity	2/319	75/18722	0.366365048062771	0.483973879365698	TMSB4X/IFNGR2	2
GO:0006911	phagocytosis, engulfment	3/319	127/18722	0.368107170405055	0.486119041932278	C3/THBS1/NCKAP1L	3
GO:0003401	axis elongation	1/319	27/18722	0.371448120763468	0.487244168621129	AREG	1
GO:0010561	negative regulation of glycoprotein biosynthetic process	1/319	27/18722	0.371448120763468	0.487244168621129	HBEGF	1
GO:0010894	negative regulation of steroid biosynthetic process	1/319	27/18722	0.371448120763468	0.487244168621129	APOE	1
GO:0018195	peptidyl-arginine modification	1/319	27/18722	0.371448120763468	0.487244168621129	PRMT9	1
GO:0031954	positive regulation of protein autophosphorylation	1/319	27/18722	0.371448120763468	0.487244168621129	VEGFA	1
GO:0032781	positive regulation of ATPase activity	1/319	27/18722	0.371448120763468	0.487244168621129	ATP1B3	1
GO:0032967	positive regulation of collagen biosynthetic process	1/319	27/18722	0.371448120763468	0.487244168621129	RGCC	1
GO:0034698	response to gonadotropin	1/319	27/18722	0.371448120763468	0.487244168621129	ICAM1	1
GO:0035116	embryonic hindlimb morphogenesis	1/319	27/18722	0.371448120763468	0.487244168621129	CTNNB1	1
GO:0039529	RIG-I signaling pathway	1/319	27/18722	0.371448120763468	0.487244168621129	BIRC3	1
GO:0042104	positive regulation of activated T cell proliferation	1/319	27/18722	0.371448120763468	0.487244168621129	HMGB1	1
GO:0042402	cellular biogenic amine catabolic process	1/319	27/18722	0.371448120763468	0.487244168621129	SAT1	1
GO:0045830	positive regulation of isotype switching	1/319	27/18722	0.371448120763468	0.487244168621129	STAT6	1
GO:0048520	positive regulation of behavior	1/319	27/18722	0.371448120763468	0.487244168621129	NR4A3	1
GO:0051953	negative regulation of amine transport	1/319	27/18722	0.371448120763468	0.487244168621129	SNCA	1
GO:0070861	regulation of protein exit from endoplasmic reticulum	1/319	27/18722	0.371448120763468	0.487244168621129	CD81	1
GO:1901018	positive regulation of potassium ion transmembrane transporter activity	1/319	27/18722	0.371448120763468	0.487244168621129	ATP1B3	1
GO:1902883	negative regulation of response to oxidative stress	1/319	27/18722	0.371448120763468	0.487244168621129	NR4A3	1
GO:1903205	regulation of hydrogen peroxide-induced cell death	1/319	27/18722	0.371448120763468	0.487244168621129	NR4A3	1
GO:1903421	regulation of synaptic vesicle recycling	1/319	27/18722	0.371448120763468	0.487244168621129	SNCA	1
GO:1903859	regulation of dendrite extension	1/319	27/18722	0.371448120763468	0.487244168621129	CXCR4	1
GO:0006479	protein methylation	4/319	181/18722	0.371813409647817	0.487412285415235	ETF1/CTNNB1/BTG1/PRMT9	4
GO:0008213	protein alkylation	4/319	181/18722	0.371813409647817	0.487412285415235	ETF1/CTNNB1/BTG1/PRMT9	4
GO:0021536	diencephalon development	2/319	76/18722	0.372483497748072	0.487979496253131	NR4A2/HES1	2
GO:0032543	mitochondrial translation	2/319	76/18722	0.372483497748072	0.487979496253131	MRPS21/MRPL52	2
GO:0048738	cardiac muscle tissue development	5/319	236/18722	0.375328800046386	0.491550397257309	KDM6B/VEGFA/PIM1/ID2/HNRNPU	5
GO:0007093	mitotic cell cycle checkpoint signaling	3/319	129/18722	0.377371379135954	0.494068069945194	DUSP1/CDKN1A/SYF2	3
GO:0006367	transcription initiation from RNA polymerase II promoter	2/319	77/18722	0.378578120284039	0.49501738310677	HMGB1/MED13	2
GO:0021675	nerve development	2/319	77/18722	0.378578120284039	0.49501738310677	CTNNB1/HES1	2
GO:0031016	pancreas development	2/319	77/18722	0.378578120284039	0.49501738310677	CTNNB1/HES1	2
GO:0032418	lysosome localization	2/319	77/18722	0.378578120284039	0.49501738310677	HMOX1/NR4A3	2
GO:1901617	organic hydroxy compound biosynthetic process	5/319	237/18722	0.378707438400219	0.495029023613132	NR4A2/TNF/SNCA/PLEK/APOE	5
GO:0006352	DNA-templated transcription, initiation	3/319	130/18722	0.38199324458213	0.495932644387367	JUN/HMGB1/MED13	3
GO:0015918	sterol transport	3/319	130/18722	0.38199324458213	0.495932644387367	NFKBIA/APOE/APOC1	3
GO:0051259	protein complex oligomerization	5/319	238/18722	0.382085701786032	0.495932644387367	SOD2/PRNP/SNCA/ISG15/HLA-DRB1	5
GO:0000303	response to superoxide	1/319	28/18722	0.382173344057207	0.495932644387367	SOD2	1
GO:0000423	mitophagy	1/319	28/18722	0.382173344057207	0.495932644387367	MAP1LC3B	1
GO:0000470	maturation of LSU-rRNA	1/319	28/18722	0.382173344057207	0.495932644387367	RPL7	1
GO:0001945	lymph vessel development	1/319	28/18722	0.382173344057207	0.495932644387367	VEGFA	1
GO:0002313	mature B cell differentiation involved in immune response	1/319	28/18722	0.382173344057207	0.495932644387367	GPR183	1
GO:0003156	regulation of animal organ formation	1/319	28/18722	0.382173344057207	0.495932644387367	CTNNB1	1
GO:0006972	hyperosmotic response	1/319	28/18722	0.382173344057207	0.495932644387367	YBX3	1
GO:0007205	protein kinase C-activating G protein-coupled receptor signaling pathway	1/319	28/18722	0.382173344057207	0.495932644387367	DGKZ	1
GO:0007271	synaptic transmission, cholinergic	1/319	28/18722	0.382173344057207	0.495932644387367	APOE	1
GO:0010714	positive regulation of collagen metabolic process	1/319	28/18722	0.382173344057207	0.495932644387367	RGCC	1
GO:0031440	regulation of mRNA 3'-end processing	1/319	28/18722	0.382173344057207	0.495932644387367	YTHDC1	1
GO:0032801	receptor catabolic process	1/319	28/18722	0.382173344057207	0.495932644387367	APOE	1
GO:0034123	positive regulation of toll-like receptor signaling pathway	1/319	28/18722	0.382173344057207	0.495932644387367	HMGB1	1
GO:0046426	negative regulation of receptor signaling pathway via JAK-STAT	1/319	28/18722	0.382173344057207	0.495932644387367	SOCS3	1
GO:0060325	face morphogenesis	1/319	28/18722	0.382173344057207	0.495932644387367	CSRNP1	1
GO:0060765	regulation of androgen receptor signaling pathway	1/319	28/18722	0.382173344057207	0.495932644387367	DDX5	1
GO:0070076	histone lysine demethylation	1/319	28/18722	0.382173344057207	0.495932644387367	KDM6B	1
GO:1903020	positive regulation of glycoprotein metabolic process	1/319	28/18722	0.382173344057207	0.495932644387367	CTNNB1	1
GO:1903649	regulation of cytoplasmic transport	1/319	28/18722	0.382173344057207	0.495932644387367	SNX3	1
GO:1990776	response to angiotensin	1/319	28/18722	0.382173344057207	0.495932644387367	PTGS2	1
GO:0055001	muscle cell development	4/319	184/18722	0.383399303468467	0.497366530943158	VEGFA/HNRNPU/HES1/PPP3CA	4
GO:0019319	hexose biosynthetic process	2/319	78/18722	0.384647951776621	0.498828936830817	ATF3/PGK1	2
GO:0050853	B cell receptor signaling pathway	3/319	131/18722	0.386607543438938	0.50121211323793	CD81/MNDA/NCKAP1L	3
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	2/319	79/18722	0.390692067872349	0.504990922823018	MYADM/LIMS1	2
GO:0060420	regulation of heart growth	2/319	79/18722	0.390692067872349	0.504990922823018	PIM1/BASP1	2
GO:0000305	response to oxygen radical	1/319	29/18722	0.392716122662415	0.504990922823018	SOD2	1
GO:0001773	myeloid dendritic cell activation	1/319	29/18722	0.392716122662415	0.504990922823018	HMGB1	1
GO:0002360	T cell lineage commitment	1/319	29/18722	0.392716122662415	0.504990922823018	STAT6	1
GO:0002862	negative regulation of inflammatory response to antigenic stimulus	1/319	29/18722	0.392716122662415	0.504990922823018	HLA-DRB1	1
GO:0005979	regulation of glycogen biosynthetic process	1/319	29/18722	0.392716122662415	0.504990922823018	IRS2	1
GO:0007143	female meiotic nuclear division	1/319	29/18722	0.392716122662415	0.504990922823018	EREG	1
GO:0009310	amine catabolic process	1/319	29/18722	0.392716122662415	0.504990922823018	SAT1	1
GO:0010458	exit from mitosis	1/319	29/18722	0.392716122662415	0.504990922823018	RGCC	1
GO:0010592	positive regulation of lamellipodium assembly	1/319	29/18722	0.392716122662415	0.504990922823018	BRK1	1
GO:0010962	regulation of glucan biosynthetic process	1/319	29/18722	0.392716122662415	0.504990922823018	IRS2	1
GO:0021591	ventricular system development	1/319	29/18722	0.392716122662415	0.504990922823018	ANP32B	1
GO:0021772	olfactory bulb development	1/319	29/18722	0.392716122662415	0.504990922823018	ID2	1
GO:0031069	hair follicle morphogenesis	1/319	29/18722	0.392716122662415	0.504990922823018	CTNNB1	1
GO:0032372	negative regulation of sterol transport	1/319	29/18722	0.392716122662415	0.504990922823018	APOC1	1
GO:0032375	negative regulation of cholesterol transport	1/319	29/18722	0.392716122662415	0.504990922823018	APOC1	1
GO:0033028	myeloid cell apoptotic process	1/319	29/18722	0.392716122662415	0.504990922823018	HCAR2	1
GO:0035066	positive regulation of histone acetylation	1/319	29/18722	0.392716122662415	0.504990922823018	IL1B	1
GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	1/319	29/18722	0.392716122662415	0.504990922823018	RGCC	1
GO:0048265	response to pain	1/319	29/18722	0.392716122662415	0.504990922823018	THBS1	1
GO:0051654	establishment of mitochondrion localization	1/319	29/18722	0.392716122662415	0.504990922823018	HIF1A	1
GO:0072539	T-helper 17 cell differentiation	1/319	29/18722	0.392716122662415	0.504990922823018	NFKBIZ	1
GO:0095500	acetylcholine receptor signaling pathway	1/319	29/18722	0.392716122662415	0.504990922823018	RGS10	1
GO:2000406	positive regulation of T cell migration	1/319	29/18722	0.392716122662415	0.504990922823018	CCL20	1
GO:2001032	regulation of double-strand break repair via nonhomologous end joining	1/319	29/18722	0.392716122662415	0.504990922823018	DEK	1
GO:0006887	exocytosis	7/319	352/18722	0.393277861016653	0.505555124027349	CCL3/STX11/SNCA/HMOX1/PLEK/NR4A3/NCKAP1L	7
GO:0033044	regulation of chromosome organization	4/319	187/18722	0.394960936834345	0.507559991036571	DUSP1/HNRNPA1/CTNNB1/HNRNPU	4
GO:0009855	determination of bilateral symmetry	3/319	133/18722	0.395811287456313	0.508493813354033	HIF1A/CTNNB1/TMEM107	3
GO:0031346	positive regulation of cell projection organization	7/319	353/18722	0.396064595276725	0.508660278407565	FN1/VEGFA/BRK1/SNX3/SKIL/SEMA4D/APOE	7
GO:0016358	dendrite development	5/319	243/18722	0.398962835106335	0.510807654800269	PHACTR1/YWHAH/SEMA4D/APOE/PPP3CA	5
GO:0009799	specification of symmetry	3/319	134/18722	0.400399683759845	0.510807654800269	HIF1A/CTNNB1/TMEM107	3
GO:0042552	myelination	3/319	134/18722	0.400399683759845	0.510807654800269	CXCR4/CTNNB1/TYMP	3
GO:0001942	hair follicle development	2/319	81/18722	0.402699647825853	0.510807654800269	TNF/CTNNB1	2
GO:0001960	negative regulation of cytokine-mediated signaling pathway	2/319	81/18722	0.402699647825853	0.510807654800269	IL1RN/ISG15	2
GO:0044773	mitotic DNA damage checkpoint signaling	2/319	81/18722	0.402699647825853	0.510807654800269	CDKN1A/SYF2	2
GO:0051149	positive regulation of muscle cell differentiation	2/319	81/18722	0.402699647825853	0.510807654800269	SOD2/PIAS1	2
GO:1903533	regulation of protein targeting	2/319	81/18722	0.402699647825853	0.510807654800269	BNIP3L/PRNP	2
GO:0003299	muscle hypertrophy in response to stress	1/319	30/18722	0.403079550516194	0.510807654800269	PPP3CA	1
GO:0006884	cell volume homeostasis	1/319	30/18722	0.403079550516194	0.510807654800269	NPM1	1
GO:0007202	activation of phospholipase C activity	1/319	30/18722	0.403079550516194	0.510807654800269	C5AR1	1
GO:0008209	androgen metabolic process	1/319	30/18722	0.403079550516194	0.510807654800269	SPP1	1
GO:0009264	deoxyribonucleotide catabolic process	1/319	30/18722	0.403079550516194	0.510807654800269	TYMP	1
GO:0010453	regulation of cell fate commitment	1/319	30/18722	0.403079550516194	0.510807654800269	HES1	1
GO:0010800	positive regulation of peptidyl-threonine phosphorylation	1/319	30/18722	0.403079550516194	0.510807654800269	RIPK2	1
GO:0014887	cardiac muscle adaptation	1/319	30/18722	0.403079550516194	0.510807654800269	PPP3CA	1
GO:0014898	cardiac muscle hypertrophy in response to stress	1/319	30/18722	0.403079550516194	0.510807654800269	PPP3CA	1
GO:0019674	NAD metabolic process	1/319	30/18722	0.403079550516194	0.510807654800269	LDHA	1
GO:0031571	mitotic G1 DNA damage checkpoint signaling	1/319	30/18722	0.403079550516194	0.510807654800269	CDKN1A	1
GO:0032480	negative regulation of type I interferon production	1/319	30/18722	0.403079550516194	0.510807654800269	NMI	1
GO:0033137	negative regulation of peptidyl-serine phosphorylation	1/319	30/18722	0.403079550516194	0.510807654800269	DDIT4	1
GO:0034390	smooth muscle cell apoptotic process	1/319	30/18722	0.403079550516194	0.510807654800269	SOD2	1
GO:0034391	regulation of smooth muscle cell apoptotic process	1/319	30/18722	0.403079550516194	0.510807654800269	SOD2	1
GO:0034694	response to prostaglandin	1/319	30/18722	0.403079550516194	0.510807654800269	PTGER4	1
GO:0036296	response to increased oxygen levels	1/319	30/18722	0.403079550516194	0.510807654800269	CDKN1A	1
GO:0043304	regulation of mast cell degranulation	1/319	30/18722	0.403079550516194	0.510807654800269	HMOX1	1
GO:0044788	modulation by host of viral process	1/319	30/18722	0.403079550516194	0.510807654800269	APOE	1
GO:0045070	positive regulation of viral genome replication	1/319	30/18722	0.403079550516194	0.510807654800269	IFIT1	1
GO:0045939	negative regulation of steroid metabolic process	1/319	30/18722	0.403079550516194	0.510807654800269	APOE	1
GO:0048147	negative regulation of fibroblast proliferation	1/319	30/18722	0.403079550516194	0.510807654800269	FTH1	1
GO:0048240	sperm capacitation	1/319	30/18722	0.403079550516194	0.510807654800269	DEFB1	1
GO:0048799	animal organ maturation	1/319	30/18722	0.403079550516194	0.510807654800269	SEMA4D	1
GO:0051125	regulation of actin nucleation	1/319	30/18722	0.403079550516194	0.510807654800269	BRK1	1
GO:0051968	positive regulation of synaptic transmission, glutamatergic	1/319	30/18722	0.403079550516194	0.510807654800269	PTGS2	1
GO:0060218	hematopoietic stem cell differentiation	1/319	30/18722	0.403079550516194	0.510807654800269	OSM	1
GO:0060603	mammary gland duct morphogenesis	1/319	30/18722	0.403079550516194	0.510807654800269	AREG	1
GO:0061311	cell surface receptor signaling pathway involved in heart development	1/319	30/18722	0.403079550516194	0.510807654800269	CTNNB1	1
GO:0090151	establishment of protein localization to mitochondrial membrane	1/319	30/18722	0.403079550516194	0.510807654800269	TOMM22	1
GO:0090314	positive regulation of protein targeting to membrane	1/319	30/18722	0.403079550516194	0.510807654800269	PRNP	1
GO:0140058	neuron projection arborization	1/319	30/18722	0.403079550516194	0.510807654800269	PHACTR1	1
GO:1902751	positive regulation of cell cycle G2/M phase transition	1/319	30/18722	0.403079550516194	0.510807654800269	NPM1	1
GO:1903019	negative regulation of glycoprotein metabolic process	1/319	30/18722	0.403079550516194	0.510807654800269	HBEGF	1
GO:2000648	positive regulation of stem cell proliferation	1/319	30/18722	0.403079550516194	0.510807654800269	HNRNPU	1
GO:0042157	lipoprotein metabolic process	3/319	135/18722	0.404978415620328	0.513055860282024	OLR1/APOE/APOC1	3
GO:0008543	fibroblast growth factor receptor signaling pathway	2/319	82/18722	0.408661451260046	0.517084403241012	CTNNB1/THBS1	2
GO:0016575	histone deacetylation	2/319	82/18722	0.408661451260046	0.517084403241012	VEGFA/BCL6	2
GO:0046364	monosaccharide biosynthetic process	2/319	82/18722	0.408661451260046	0.517084403241012	ATF3/PGK1	2
GO:2001252	positive regulation of chromosome organization	2/319	82/18722	0.408661451260046	0.517084403241012	HNRNPA1/CTNNB1	2
GO:0007272	ensheathment of neurons	3/319	136/18722	0.409546986396041	0.517408623563038	CXCR4/CTNNB1/TYMP	3
GO:0008366	axon ensheathment	3/319	136/18722	0.409546986396041	0.517408623563038	CXCR4/CTNNB1/TYMP	3
GO:0098876	vesicle-mediated transport to the plasma membrane	3/319	136/18722	0.409546986396041	0.517408623563038	SNX3/ARL4C/VAMP5	3
GO:0099024	plasma membrane invagination	3/319	136/18722	0.409546986396041	0.517408623563038	C3/THBS1/NCKAP1L	3
GO:1900180	regulation of protein localization to nucleus	3/319	136/18722	0.409546986396041	0.517408623563038	NPM1/PTGS2/HSP90AB1	3
GO:0015849	organic acid transport	6/319	303/18722	0.413020503498105	0.518760084668585	IL1B/PLIN2/IRS2/SNCA/APOE/THBS1	6
GO:0060070	canonical Wnt signaling pathway	6/319	303/18722	0.413020503498105	0.518760084668585	KLF4/NR4A2/CTNNB1/TLE3/EGR1/APOE	6
GO:0016577	histone demethylation	1/319	31/18722	0.413266669250697	0.518760084668585	KDM6B	1
GO:0021988	olfactory lobe development	1/319	31/18722	0.413266669250697	0.518760084668585	ID2	1
GO:0030201	heparan sulfate proteoglycan metabolic process	1/319	31/18722	0.413266669250697	0.518760084668585	CTNNB1	1
GO:0033006	regulation of mast cell activation involved in immune response	1/319	31/18722	0.413266669250697	0.518760084668585	HMOX1	1
GO:0035115	embryonic forelimb morphogenesis	1/319	31/18722	0.413266669250697	0.518760084668585	CTNNB1	1
GO:0036474	cell death in response to hydrogen peroxide	1/319	31/18722	0.413266669250697	0.518760084668585	NR4A3	1
GO:0044819	mitotic G1/S transition checkpoint signaling	1/319	31/18722	0.413266669250697	0.518760084668585	CDKN1A	1
GO:0045987	positive regulation of smooth muscle contraction	1/319	31/18722	0.413266669250697	0.518760084668585	PTGS2	1
GO:0046386	deoxyribose phosphate catabolic process	1/319	31/18722	0.413266669250697	0.518760084668585	TYMP	1
GO:0048384	retinoic acid receptor signaling pathway	1/319	31/18722	0.413266669250697	0.518760084668585	KLF2	1
GO:0051569	regulation of histone H3-K4 methylation	1/319	31/18722	0.413266669250697	0.518760084668585	CTNNB1	1
GO:0055075	potassium ion homeostasis	1/319	31/18722	0.413266669250697	0.518760084668585	ATP1B3	1
GO:0060045	positive regulation of cardiac muscle cell proliferation	1/319	31/18722	0.413266669250697	0.518760084668585	PIM1	1
GO:0060390	regulation of SMAD protein signal transduction	1/319	31/18722	0.413266669250697	0.518760084668585	TOB1	1
GO:0070723	response to cholesterol	1/319	31/18722	0.413266669250697	0.518760084668585	CCL3	1
GO:0090162	establishment of epithelial cell polarity	1/319	31/18722	0.413266669250697	0.518760084668585	HES1	1
GO:1900027	regulation of ruffle assembly	1/319	31/18722	0.413266669250697	0.518760084668585	ICAM1	1
GO:1905144	response to acetylcholine	1/319	31/18722	0.413266669250697	0.518760084668585	RGS10	1
GO:1905145	cellular response to acetylcholine	1/319	31/18722	0.413266669250697	0.518760084668585	RGS10	1
GO:0010977	negative regulation of neuron projection development	3/319	137/18722	0.414104910422403	0.519474801532023	SEMA4D/SPP1/APOE	3
GO:0090090	negative regulation of canonical Wnt signaling pathway	3/319	137/18722	0.414104910422403	0.519474801532023	TLE3/EGR1/APOE	3
GO:0046785	microtubule polymerization	2/319	83/18722	0.41459421645015	0.519474801532023	MAPRE1/SNCA	2
GO:0048678	response to axon injury	2/319	83/18722	0.41459421645015	0.519474801532023	KLF4/SPP1	2
GO:0051899	membrane depolarization	2/319	83/18722	0.41459421645015	0.519474801532023	JUN/YWHAH	2
GO:1901292	nucleoside phosphate catabolic process	2/319	83/18722	0.41459421645015	0.519474801532023	PDE4B/TYMP	2
GO:1901988	negative regulation of cell cycle phase transition	5/319	249/18722	0.419152877889072	0.52502665478427	KLF4/DUSP1/CDKN1A/SYF2/RGCC	5
GO:0002088	lens development in camera-type eye	2/319	84/18722	0.420497201324827	0.525110569455153	CTNNB1/SKIL	2
GO:0006112	energy reserve metabolic process	2/319	84/18722	0.420497201324827	0.525110569455153	IRS2/HMGB1	2
GO:0010660	regulation of muscle cell apoptotic process	2/319	84/18722	0.420497201324827	0.525110569455153	SOD2/HMOX1	2
GO:0022404	molting cycle process	2/319	84/18722	0.420497201324827	0.525110569455153	TNF/CTNNB1	2
GO:0022405	hair cycle process	2/319	84/18722	0.420497201324827	0.525110569455153	TNF/CTNNB1	2
GO:0042310	vasoconstriction	2/319	84/18722	0.420497201324827	0.525110569455153	ICAM1/PTGS2	2
GO:0061157	mRNA destabilization	2/319	84/18722	0.420497201324827	0.525110569455153	ZFP36/TOB1	2
GO:0097061	dendritic spine organization	2/319	84/18722	0.420497201324827	0.525110569455153	PRNP/APOE	2
GO:0098586	cellular response to virus	2/319	84/18722	0.420497201324827	0.525110569455153	BIRC3/HIF1A	2
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	2/319	84/18722	0.420497201324827	0.525110569455153	KLF4/CDKN1A	2
GO:0016579	protein deubiquitination	3/319	139/18722	0.423186929963683	0.526347854920079	TNFAIP3/OTUD1/JOSD1	3
GO:0030216	keratinocyte differentiation	3/319	139/18722	0.423186929963683	0.526347854920079	FOSL2/ZFP36/EREG	3
GO:0007435	salivary gland morphogenesis	1/319	32/18722	0.423280469074624	0.526347854920079	TNF	1
GO:0008156	negative regulation of DNA replication	1/319	32/18722	0.423280469074624	0.526347854920079	BCL6	1
GO:0009954	proximal/distal pattern formation	1/319	32/18722	0.423280469074624	0.526347854920079	CTNNB1	1
GO:0030431	sleep	1/319	32/18722	0.423280469074624	0.526347854920079	FOS	1
GO:0033687	osteoblast proliferation	1/319	32/18722	0.423280469074624	0.526347854920079	JUNB	1
GO:0035883	enteroendocrine cell differentiation	1/319	32/18722	0.423280469074624	0.526347854920079	HES1	1
GO:0046475	glycerophospholipid catabolic process	1/319	32/18722	0.423280469074624	0.526347854920079	APOC1	1
GO:0050685	positive regulation of mRNA processing	1/319	32/18722	0.423280469074624	0.526347854920079	NCL	1
GO:0060323	head morphogenesis	1/319	32/18722	0.423280469074624	0.526347854920079	CSRNP1	1
GO:0061037	negative regulation of cartilage development	1/319	32/18722	0.423280469074624	0.526347854920079	CTNNB1	1
GO:0071875	adrenergic receptor signaling pathway	1/319	32/18722	0.423280469074624	0.526347854920079	PDE4B	1
GO:1905476	negative regulation of protein localization to membrane	1/319	32/18722	0.423280469074624	0.526347854920079	GBP1	1
GO:0030705	cytoskeleton-dependent intracellular transport	4/319	195/18722	0.42560422476945	0.529077401883039	HIF1A/HNRNPU/TUBA1A/TUBB	4
GO:0044774	mitotic DNA integrity checkpoint signaling	2/319	85/18722	0.426369697349061	0.529548587855586	CDKN1A/SYF2	2
GO:0055013	cardiac muscle cell development	2/319	85/18722	0.426369697349061	0.529548587855586	VEGFA/HNRNPU	2
GO:0098773	skin epidermis development	2/319	85/18722	0.426369697349061	0.529548587855586	TNF/CTNNB1	2
GO:0046165	alcohol biosynthetic process	3/319	140/18722	0.427710108289047	0.531052931191867	SNCA/PLEK/APOE	3
GO:0045664	regulation of neuron differentiation	4/319	196/18722	0.429409687301625	0.533002181309475	YWHAH/BCL6/ID2/HES1	4
GO:0035023	regulation of Rho protein signal transduction	2/319	86/18722	0.432211028603156	0.533265142350905	BCL6/APOE	2
GO:1903510	mucopolysaccharide metabolic process	2/319	86/18722	0.432211028603156	0.533265142350905	IL1B/PIM1	2
GO:0008584	male gonad development	3/319	141/18722	0.432220805309521	0.533265142350905	ICAM1/HMGB2/YBX3	3
GO:0048284	organelle fusion	3/319	141/18722	0.432220805309521	0.533265142350905	CHMP2B/STX11/SNCA	3
GO:0002335	mature B cell differentiation	1/319	33/18722	0.43312388963991	0.533265142350905	GPR183	1
GO:0002431	Fc receptor mediated stimulatory signaling pathway	1/319	33/18722	0.43312388963991	0.533265142350905	NR4A3	1
GO:0003382	epithelial cell morphogenesis	1/319	33/18722	0.43312388963991	0.533265142350905	RILPL2	1
GO:0006482	protein demethylation	1/319	33/18722	0.43312388963991	0.533265142350905	KDM6B	1
GO:0006654	phosphatidic acid biosynthetic process	1/319	33/18722	0.43312388963991	0.533265142350905	DGKZ	1
GO:0008214	protein dealkylation	1/319	33/18722	0.43312388963991	0.533265142350905	KDM6B	1
GO:0010165	response to X-ray	1/319	33/18722	0.43312388963991	0.533265142350905	CDKN1A	1
GO:0010259	multicellular organism aging	1/319	33/18722	0.43312388963991	0.533265142350905	SERP1	1
GO:0010984	regulation of lipoprotein particle clearance	1/319	33/18722	0.43312388963991	0.533265142350905	APOC1	1
GO:0031116	positive regulation of microtubule polymerization	1/319	33/18722	0.43312388963991	0.533265142350905	MAPRE1	1
GO:0033198	response to ATP	1/319	33/18722	0.43312388963991	0.533265142350905	PTGS2	1
GO:0034110	regulation of homotypic cell-cell adhesion	1/319	33/18722	0.43312388963991	0.533265142350905	PLAUR	1
GO:0050901	leukocyte tethering or rolling	1/319	33/18722	0.43312388963991	0.533265142350905	TNF	1
GO:0050974	detection of mechanical stimulus involved in sensory perception	1/319	33/18722	0.43312388963991	0.533265142350905	CXCR4	1
GO:0060122	inner ear receptor cell stereocilium organization	1/319	33/18722	0.43312388963991	0.533265142350905	HES1	1
GO:0071295	cellular response to vitamin	1/319	33/18722	0.43312388963991	0.533265142350905	PIM1	1
GO:0071539	protein localization to centrosome	1/319	33/18722	0.43312388963991	0.533265142350905	MAPRE1	1
GO:0099174	regulation of presynapse organization	1/319	33/18722	0.43312388963991	0.533265142350905	SNCA	1
GO:0110110	positive regulation of animal organ morphogenesis	1/319	33/18722	0.43312388963991	0.533265142350905	CTNNB1	1
GO:1901976	regulation of cell cycle checkpoint	1/319	33/18722	0.43312388963991	0.533265142350905	DUSP1	1
GO:1902275	regulation of chromatin organization	1/319	33/18722	0.43312388963991	0.533265142350905	HNRNPU	1
GO:1905606	regulation of presynapse assembly	1/319	33/18722	0.43312388963991	0.533265142350905	SNCA	1
GO:2000036	regulation of stem cell population maintenance	1/319	33/18722	0.43312388963991	0.533265142350905	ZNF706	1
GO:0046546	development of primary male sexual characteristics	3/319	142/18722	0.436718588971153	0.537369086878303	ICAM1/HMGB2/YBX3	3
GO:0097553	calcium ion transmembrane import into cytosol	3/319	142/18722	0.436718588971153	0.537369086878303	CCL3/PRNP/SNCA	3
GO:0009150	purine ribonucleotide metabolic process	7/319	368/18722	0.437793502535792	0.538487585131859	TMSB4X/DDIT4/HIF1A/PDE4B/LDHA/PGK1/SNCA	7
GO:0061014	positive regulation of mRNA catabolic process	2/319	87/18722	0.438020550883225	0.538487585131859	ZFP36/TOB1	2
GO:0150104	transport across blood-brain barrier	2/319	87/18722	0.438020550883225	0.538487585131859	SLC2A3/APOE	2
GO:0001662	behavioral fear response	1/319	34/18722	0.44279982089385	0.539682793861434	APOE	1
GO:0002446	neutrophil mediated immunity	1/319	34/18722	0.44279982089385	0.539682793861434	TREM1	1
GO:0006356	regulation of transcription by RNA polymerase I	1/319	34/18722	0.44279982089385	0.539682793861434	NCL	1
GO:0007431	salivary gland development	1/319	34/18722	0.44279982089385	0.539682793861434	TNF	1
GO:0009112	nucleobase metabolic process	1/319	34/18722	0.44279982089385	0.539682793861434	TYMP	1
GO:0009303	rRNA transcription	1/319	34/18722	0.44279982089385	0.539682793861434	NCL	1
GO:0010661	positive regulation of muscle cell apoptotic process	1/319	34/18722	0.44279982089385	0.539682793861434	SOD2	1
GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	1/319	34/18722	0.44279982089385	0.539682793861434	CCL3	1
GO:0016242	negative regulation of macroautophagy	1/319	34/18722	0.44279982089385	0.539682793861434	HMOX1	1
GO:0019076	viral release from host cell	1/319	34/18722	0.44279982089385	0.539682793861434	CHMP2B	1
GO:0030851	granulocyte differentiation	1/319	34/18722	0.44279982089385	0.539682793861434	TRIB1	1
GO:0031128	developmental induction	1/319	34/18722	0.44279982089385	0.539682793861434	CTNNB1	1
GO:0034383	low-density lipoprotein particle clearance	1/319	34/18722	0.44279982089385	0.539682793861434	HMOX1	1
GO:0035137	hindlimb morphogenesis	1/319	34/18722	0.44279982089385	0.539682793861434	CTNNB1	1
GO:0035890	exit from host	1/319	34/18722	0.44279982089385	0.539682793861434	CHMP2B	1
GO:0035891	exit from host cell	1/319	34/18722	0.44279982089385	0.539682793861434	CHMP2B	1
GO:0035909	aorta morphogenesis	1/319	34/18722	0.44279982089385	0.539682793861434	HES1	1
GO:0039528	cytoplasmic pattern recognition receptor signaling pathway in response to virus	1/319	34/18722	0.44279982089385	0.539682793861434	BIRC3	1
GO:0043276	anoikis	1/319	34/18722	0.44279982089385	0.539682793861434	MCL1	1
GO:0044319	wound healing, spreading of cells	1/319	34/18722	0.44279982089385	0.539682793861434	HBEGF	1
GO:0048261	negative regulation of receptor-mediated endocytosis	1/319	34/18722	0.44279982089385	0.539682793861434	APOC1	1
GO:0048741	skeletal muscle fiber development	1/319	34/18722	0.44279982089385	0.539682793861434	PPP3CA	1
GO:0070050	neuron cellular homeostasis	1/319	34/18722	0.44279982089385	0.539682793861434	CHMP2B	1
GO:0086004	regulation of cardiac muscle cell contraction	1/319	34/18722	0.44279982089385	0.539682793861434	PDE4B	1
GO:0090075	relaxation of muscle	1/319	34/18722	0.44279982089385	0.539682793861434	PDE4B	1
GO:0090505	epiboly involved in wound healing	1/319	34/18722	0.44279982089385	0.539682793861434	HBEGF	1
GO:1904893	negative regulation of receptor signaling pathway via STAT	1/319	34/18722	0.44279982089385	0.539682793861434	SOCS3	1
GO:1990000	amyloid fibril formation	1/319	34/18722	0.44279982089385	0.539682793861434	APOE	1
GO:2000758	positive regulation of peptidyl-lysine acetylation	1/319	34/18722	0.44279982089385	0.539682793861434	IL1B	1
GO:0010232	vascular transport	2/319	88/18722	0.44379765082269	0.540418288664716	SLC2A3/APOE	2
GO:0031110	regulation of microtubule polymerization or depolymerization	2/319	88/18722	0.44379765082269	0.540418288664716	MAPRE1/SNCA	2
GO:0050779	RNA destabilization	2/319	88/18722	0.44379765082269	0.540418288664716	ZFP36/TOB1	2
GO:0034660	ncRNA metabolic process	9/319	485/18722	0.44498674575518	0.54170580746211	SBDS/LSM6/FRG1/SSB/RPS15/RPL7/RPS28/RPL5/RPS6	9
GO:0001654	eye development	7/319	371/18722	0.446100417072062	0.542900774003329	KLF4/HIF1A/VEGFA/CTNNB1/SKIL/HMGN1/HMGB1	7
GO:0010657	muscle cell apoptotic process	2/319	89/18722	0.449541745034374	0.546765122436779	SOD2/HMOX1	2
GO:0014910	regulation of smooth muscle cell migration	2/319	89/18722	0.449541745034374	0.546765122436779	TRIB1/NR4A3	2
GO:0007269	neurotransmitter secretion	3/319	145/18722	0.450130295419829	0.546897337706587	NR4A1/STX11/SNCA	3
GO:0099643	signal release from synapse	3/319	145/18722	0.450130295419829	0.546897337706587	NR4A1/STX11/SNCA	3
GO:0048285	organelle fission	9/319	488/18722	0.452243210258642	0.546897337706587	DUSP1/IL1B/CHMP1B/CHMP2B/CHMP5/HNRNPU/EREG/RGCC/IL1A	9
GO:0002209	behavioral defense response	1/319	35/18722	0.452311103916905	0.546897337706587	APOE	1
GO:0006298	mismatch repair	1/319	35/18722	0.452311103916905	0.546897337706587	HMGB1	1
GO:0006739	NADP metabolic process	1/319	35/18722	0.452311103916905	0.546897337706587	DCXR	1
GO:0008608	attachment of spindle microtubules to kinetochore	1/319	35/18722	0.452311103916905	0.546897337706587	HNRNPU	1
GO:0010765	positive regulation of sodium ion transport	1/319	35/18722	0.452311103916905	0.546897337706587	ATP1B3	1
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	1/319	35/18722	0.452311103916905	0.546897337706587	HSP90AB1	1
GO:0039694	viral RNA genome replication	1/319	35/18722	0.452311103916905	0.546897337706587	CXCL8	1
GO:0042462	eye photoreceptor cell development	1/319	35/18722	0.452311103916905	0.546897337706587	VEGFA	1
GO:0045454	cell redox homeostasis	1/319	35/18722	0.452311103916905	0.546897337706587	PRDX3	1
GO:0045922	negative regulation of fatty acid metabolic process	1/319	35/18722	0.452311103916905	0.546897337706587	APOC1	1
GO:0071108	protein K48-linked deubiquitination	1/319	35/18722	0.452311103916905	0.546897337706587	TNFAIP3	1
GO:0090181	regulation of cholesterol metabolic process	1/319	35/18722	0.452311103916905	0.546897337706587	APOE	1
GO:0090504	epiboly	1/319	35/18722	0.452311103916905	0.546897337706587	HBEGF	1
GO:0098810	neurotransmitter reuptake	1/319	35/18722	0.452311103916905	0.546897337706587	SNCA	1
GO:1903514	release of sequestered calcium ion into cytosol by endoplasmic reticulum	1/319	35/18722	0.452311103916905	0.546897337706587	CCL3	1
GO:1905508	protein localization to microtubule organizing center	1/319	35/18722	0.452311103916905	0.546897337706587	MAPRE1	1
GO:1905898	positive regulation of response to endoplasmic reticulum stress	1/319	35/18722	0.452311103916905	0.546897337706587	PMAIP1	1
GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	3/319	146/18722	0.454572312631614	0.549469796303607	PDE4B/PTGER4/PF4	3
GO:0002028	regulation of sodium ion transport	2/319	90/18722	0.455252279272705	0.550129958874218	YWHAH/ATP1B3	2
GO:0006260	DNA replication	5/319	260/18722	0.455837431364063	0.550513419605659	JUN/BCL6/EREG/SET/NAP1L1	5
GO:0090150	establishment of protein localization to membrane	5/319	260/18722	0.455837431364063	0.550513419605659	TOMM22/PRNP/RILPL2/VAMP5/NACA	5
GO:0010498	proteasomal protein catabolic process	9/319	490/18722	0.45707352574277	0.55184413049296	TRIB1/GABARAP/CTNNB1/PMAIP1/HSP90AB1/SUMO2/RNF19B/APOE/PIAS1	9
GO:0034765	regulation of ion transmembrane transport	9/319	491/18722	0.459486234266326	0.553804040271262	TMSB4X/YWHAH/ATP1B3/PPIF/PDE4B/PRNP/VMP1/SNCA/IFNGR2	9
GO:0051492	regulation of stress fiber assembly	2/319	91/18722	0.460928727615625	0.553804040271262	PTGER4/RGCC	2
GO:0051983	regulation of chromosome segregation	2/319	91/18722	0.460928727615625	0.553804040271262	DUSP1/HNRNPU	2
GO:0055006	cardiac cell development	2/319	91/18722	0.460928727615625	0.553804040271262	VEGFA/HNRNPU	2
GO:0008202	steroid metabolic process	6/319	319/18722	0.461239724017914	0.553804040271262	YWHAH/TNF/EGR1/SPP1/APOE/APOC1	6
GO:0003352	regulation of cilium movement	1/319	36/18722	0.46166053174644	0.553804040271262	DEFB1	1
GO:0008207	C21-steroid hormone metabolic process	1/319	36/18722	0.46166053174644	0.553804040271262	EGR1	1
GO:0010092	specification of animal organ identity	1/319	36/18722	0.46166053174644	0.553804040271262	CTNNB1	1
GO:0010762	regulation of fibroblast migration	1/319	36/18722	0.46166053174644	0.553804040271262	THBS1	1
GO:0014046	dopamine secretion	1/319	36/18722	0.46166053174644	0.553804040271262	SNCA	1
GO:0014059	regulation of dopamine secretion	1/319	36/18722	0.46166053174644	0.553804040271262	SNCA	1
GO:0036314	response to sterol	1/319	36/18722	0.46166053174644	0.553804040271262	CCL3	1
GO:0038179	neurotrophin signaling pathway	1/319	36/18722	0.46166053174644	0.553804040271262	DDIT4	1
GO:0042119	neutrophil activation	1/319	36/18722	0.46166053174644	0.553804040271262	CXCL8	1
GO:0044060	regulation of endocrine process	1/319	36/18722	0.46166053174644	0.553804040271262	RETN	1
GO:0051354	negative regulation of oxidoreductase activity	1/319	36/18722	0.46166053174644	0.553804040271262	SNCA	1
GO:0051955	regulation of amino acid transport	1/319	36/18722	0.46166053174644	0.553804040271262	SNCA	1
GO:0070306	lens fiber cell differentiation	1/319	36/18722	0.46166053174644	0.553804040271262	SKIL	1
GO:0070897	transcription preinitiation complex assembly	1/319	36/18722	0.46166053174644	0.553804040271262	HMGB1	1
GO:0086010	membrane depolarization during action potential	1/319	36/18722	0.46166053174644	0.553804040271262	YWHAH	1
GO:0090313	regulation of protein targeting to membrane	1/319	36/18722	0.46166053174644	0.553804040271262	PRNP	1
GO:1902229	regulation of intrinsic apoptotic signaling pathway in response to DNA damage	1/319	36/18722	0.46166053174644	0.553804040271262	SKIL	1
GO:0060348	bone development	4/319	205/18722	0.463329730683234	0.555417937043939	SBDS/SEMA4D/PTGER4/TMEM107	4
GO:0035148	tube formation	3/319	148/18722	0.463411219669353	0.555417937043939	HIF1A/VEGFA/CTNNB1	3
GO:0044839	cell cycle G2/M phase transition	3/319	148/18722	0.463411219669353	0.555417937043939	CDKN1A/SYF2/NPM1	3
GO:0043588	skin development	5/319	263/18722	0.465738880911459	0.558045042094727	TNF/FOSL2/ZFP36/CTNNB1/EREG	5
GO:0007389	pattern specification process	8/319	436/18722	0.466183145014259	0.558414600569236	BHLHE40/HIF1A/CTNNB1/ETS2/BASP1/TMEM107/HES1/C3	8
GO:0043010	camera-type eye development	6/319	322/18722	0.47018420856219	0.56106314351221	KLF4/HIF1A/VEGFA/CTNNB1/SKIL/HMGN1	6
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1/319	37/18722	0.470850850186603	0.56106314351221	ETF1	1
GO:0003161	cardiac conduction system development	1/319	37/18722	0.470850850186603	0.56106314351221	ID2	1
GO:0006904	vesicle docking involved in exocytosis	1/319	37/18722	0.470850850186603	0.56106314351221	PLEK	1
GO:0014904	myotube cell development	1/319	37/18722	0.470850850186603	0.56106314351221	PPP3CA	1
GO:0030513	positive regulation of BMP signaling pathway	1/319	37/18722	0.470850850186603	0.56106314351221	HES1	1
GO:0031112	positive regulation of microtubule polymerization or depolymerization	1/319	37/18722	0.470850850186603	0.56106314351221	MAPRE1	1
GO:0032885	regulation of polysaccharide biosynthetic process	1/319	37/18722	0.470850850186603	0.56106314351221	IRS2	1
GO:0033260	nuclear DNA replication	1/319	37/18722	0.470850850186603	0.56106314351221	BCL6	1
GO:0033363	secretory granule organization	1/319	37/18722	0.470850850186603	0.56106314351221	SRGN	1
GO:0043368	positive T cell selection	1/319	37/18722	0.470850850186603	0.56106314351221	STAT6	1
GO:0045616	regulation of keratinocyte differentiation	1/319	37/18722	0.470850850186603	0.56106314351221	ZFP36	1
GO:0045730	respiratory burst	1/319	37/18722	0.470850850186603	0.56106314351221	NCF2	1
GO:0046473	phosphatidic acid metabolic process	1/319	37/18722	0.470850850186603	0.56106314351221	DGKZ	1
GO:0060428	lung epithelium development	1/319	37/18722	0.470850850186603	0.56106314351221	KLF2	1
GO:0072529	pyrimidine-containing compound catabolic process	1/319	37/18722	0.470850850186603	0.56106314351221	TYMP	1
GO:0097484	dendrite extension	1/319	37/18722	0.470850850186603	0.56106314351221	CXCR4	1
GO:1902745	positive regulation of lamellipodium organization	1/319	37/18722	0.470850850186603	0.56106314351221	BRK1	1
GO:0007589	body fluid secretion	2/319	93/18722	0.472177399770536	0.561829606499761	HIF1A/VEGFA	2
GO:0033108	mitochondrial respiratory chain complex assembly	2/319	93/18722	0.472177399770536	0.561829606499761	NDUFS5/NDUFA6	2
GO:0106027	neuron projection organization	2/319	93/18722	0.472177399770536	0.561829606499761	PRNP/APOE	2
GO:1901019	regulation of calcium ion transmembrane transporter activity	2/319	93/18722	0.472177399770536	0.561829606499761	PDE4B/VMP1	2
GO:1902807	negative regulation of cell cycle G1/S phase transition	2/319	93/18722	0.472177399770536	0.561829606499761	KLF4/CDKN1A	2
GO:0030902	hindbrain development	3/319	151/18722	0.476551346146616	0.566869960650676	CTNNB1/HES1/C5AR1	3
GO:0010389	regulation of G2/M transition of mitotic cell cycle	2/319	94/18722	0.477748706260495	0.567965567217147	CDKN1A/SYF2	2
GO:0032091	negative regulation of protein binding	2/319	94/18722	0.477748706260495	0.567965567217147	CDKN1A/IFIT1	2
GO:0007094	mitotic spindle assembly checkpoint signaling	1/319	38/18722	0.47988475860461	0.568368263504336	DUSP1	1
GO:0035136	forelimb morphogenesis	1/319	38/18722	0.47988475860461	0.568368263504336	CTNNB1	1
GO:0042491	inner ear auditory receptor cell differentiation	1/319	38/18722	0.47988475860461	0.568368263504336	HES1	1
GO:0042596	fear response	1/319	38/18722	0.47988475860461	0.568368263504336	APOE	1
GO:0046329	negative regulation of JNK cascade	1/319	38/18722	0.47988475860461	0.568368263504336	DNAJA1	1
GO:0051930	regulation of sensory perception of pain	1/319	38/18722	0.47988475860461	0.568368263504336	CCL3	1
GO:0071173	spindle assembly checkpoint signaling	1/319	38/18722	0.47988475860461	0.568368263504336	DUSP1	1
GO:0071174	mitotic spindle checkpoint signaling	1/319	38/18722	0.47988475860461	0.568368263504336	DUSP1	1
GO:0071398	cellular response to fatty acid	1/319	38/18722	0.47988475860461	0.568368263504336	FFAR2	1
GO:0072538	T-helper 17 type immune response	1/319	38/18722	0.47988475860461	0.568368263504336	NFKBIZ	1
GO:0098926	postsynaptic signal transduction	1/319	38/18722	0.47988475860461	0.568368263504336	RGS10	1
GO:1901031	regulation of response to reactive oxygen species	1/319	38/18722	0.47988475860461	0.568368263504336	NR4A3	1
GO:1903725	regulation of phospholipid metabolic process	1/319	38/18722	0.47988475860461	0.568368263504336	APOC1	1
GO:0016573	histone acetylation	3/319	152/18722	0.480898482911871	0.56924090505347	IL1B/SNCA/SET	3
GO:0021915	neural tube development	3/319	152/18722	0.480898482911871	0.56924090505347	HIF1A/TMEM107/HES1	3
GO:0001894	tissue homeostasis	5/319	268/18722	0.482118357072516	0.570520600439008	TNFAIP3/VEGFA/CTNNB1/PTGS2/SPP1	5
GO:0002532	production of molecular mediator involved in inflammatory response	2/319	95/18722	0.483284090706005	0.571406642764563	HIF1A/TNF	2
GO:0006942	regulation of striated muscle contraction	2/319	95/18722	0.483284090706005	0.571406642764563	NR4A1/PDE4B	2
GO:1901379	regulation of potassium ion transmembrane transport	2/319	95/18722	0.483284090706005	0.571406642764563	ATP1B3/PRNP	2
GO:0009259	ribonucleotide metabolic process	7/319	385/18722	0.484536349559201	0.572722522437572	TMSB4X/DDIT4/HIF1A/PDE4B/LDHA/PGK1/SNCA	7
GO:0016055	Wnt signaling pathway	8/319	444/18722	0.486567767996265	0.574958348442842	TNFAIP3/KLF4/NR4A2/CTNNB1/SNX3/TLE3/EGR1/APOE	8
GO:0001941	postsynaptic membrane organization	1/319	39/18722	0.488764910713641	0.575755747625701	APOE	1
GO:0016572	histone phosphorylation	1/319	39/18722	0.488764910713641	0.575755747625701	IL1B	1
GO:0031577	spindle checkpoint signaling	1/319	39/18722	0.488764910713641	0.575755747625701	DUSP1	1
GO:0034314	Arp2/3 complex-mediated actin nucleation	1/319	39/18722	0.488764910713641	0.575755747625701	BRK1	1
GO:0046326	positive regulation of glucose import	1/319	39/18722	0.488764910713641	0.575755747625701	IRS2	1
GO:0051154	negative regulation of striated muscle cell differentiation	1/319	39/18722	0.488764910713641	0.575755747625701	YBX1	1
GO:0051931	regulation of sensory perception	1/319	39/18722	0.488764910713641	0.575755747625701	CCL3	1
GO:1901021	positive regulation of calcium ion transmembrane transporter activity	1/319	39/18722	0.488764910713641	0.575755747625701	VMP1	1
GO:1903115	regulation of actin filament-based movement	1/319	39/18722	0.488764910713641	0.575755747625701	PDE4B	1
GO:0015914	phospholipid transport	2/319	96/18722	0.488783157191363	0.575755747625701	APOE/APOC1	2
GO:0044264	cellular polysaccharide metabolic process	2/319	96/18722	0.488783157191363	0.575755747625701	IRS2/HMGB1	2
GO:0198738	cell-cell signaling by wnt	8/319	446/18722	0.491633542031477	0.578947433770095	TNFAIP3/KLF4/NR4A2/CTNNB1/SNX3/TLE3/EGR1/APOE	8
GO:0046434	organophosphate catabolic process	3/319	155/18722	0.493836658465689	0.581375287214332	PDE4B/TYMP/APOC1	3
GO:0014909	smooth muscle cell migration	2/319	97/18722	0.494245533606291	0.581690062598186	TRIB1/NR4A3	2
GO:0007339	binding of sperm to zona pellucida	1/319	40/18722	0.497493915342573	0.582843398681482	VDAC2	1
GO:0009187	cyclic nucleotide metabolic process	1/319	40/18722	0.497493915342573	0.582843398681482	PDE4B	1
GO:0009394	2'-deoxyribonucleotide metabolic process	1/319	40/18722	0.497493915342573	0.582843398681482	TYMP	1
GO:0010863	positive regulation of phospholipase C activity	1/319	40/18722	0.497493915342573	0.582843398681482	C5AR1	1
GO:0030501	positive regulation of bone mineralization	1/319	40/18722	0.497493915342573	0.582843398681482	ISG15	1
GO:0032892	positive regulation of organic acid transport	1/319	40/18722	0.497493915342573	0.582843398681482	IL1B	1
GO:0034122	negative regulation of toll-like receptor signaling pathway	1/319	40/18722	0.497493915342573	0.582843398681482	TNFAIP3	1
GO:0043001	Golgi to plasma membrane protein transport	1/319	40/18722	0.497493915342573	0.582843398681482	VAMP5	1
GO:0044275	cellular carbohydrate catabolic process	1/319	40/18722	0.497493915342573	0.582843398681482	HMGB1	1
GO:0045022	early endosome to late endosome transport	1/319	40/18722	0.497493915342573	0.582843398681482	SNX3	1
GO:0045777	positive regulation of blood pressure	1/319	40/18722	0.497493915342573	0.582843398681482	ID2	1
GO:0045841	negative regulation of mitotic metaphase/anaphase transition	1/319	40/18722	0.497493915342573	0.582843398681482	DUSP1	1
GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	1/319	40/18722	0.497493915342573	0.582843398681482	SNCA	1
GO:0060412	ventricular septum morphogenesis	1/319	40/18722	0.497493915342573	0.582843398681482	HES1	1
GO:0071526	semaphorin-plexin signaling pathway	1/319	40/18722	0.497493915342573	0.582843398681482	SEMA4D	1
GO:1901998	toxin transport	1/319	40/18722	0.497493915342573	0.582843398681482	DNAJA1	1
GO:0006631	fatty acid metabolic process	7/319	390/18722	0.498091630786538	0.583377405744575	IL1B/IRS2/SNCA/PTGS2/NR4A3/C3/APOC1	7
GO:0007034	vacuolar transport	3/319	157/18722	0.502373060080899	0.588056847947772	CHMP1B/CHMP2B/CHMP5	3
GO:0070646	protein modification by small protein removal	3/319	157/18722	0.502373060080899	0.588056847947772	TNFAIP3/OTUD1/JOSD1	3
GO:0003300	cardiac muscle hypertrophy	2/319	99/18722	0.505058842677591	0.591032423070759	NR4A3/PPP3CA	2
GO:0007099	centriole replication	1/319	41/18722	0.506074337192789	0.59104306823851	NPM1	1
GO:0031062	positive regulation of histone methylation	1/319	41/18722	0.506074337192789	0.59104306823851	CTNNB1	1
GO:0044786	cell cycle DNA replication	1/319	41/18722	0.506074337192789	0.59104306823851	BCL6	1
GO:0050691	regulation of defense response to virus by host	1/319	41/18722	0.506074337192789	0.59104306823851	TNFAIP3	1
GO:0055023	positive regulation of cardiac muscle tissue growth	1/319	41/18722	0.506074337192789	0.59104306823851	PIM1	1
GO:0070296	sarcoplasmic reticulum calcium ion transport	1/319	41/18722	0.506074337192789	0.59104306823851	CCL3	1
GO:1901385	regulation of voltage-gated calcium channel activity	1/319	41/18722	0.506074337192789	0.59104306823851	PDE4B	1
GO:0018393	internal peptidyl-lysine acetylation	3/319	158/18722	0.506613687614588	0.59150493319613	IL1B/SNCA/SET	3
GO:0006626	protein targeting to mitochondrion	2/319	100/18722	0.51040914399815	0.595429055328148	BNIP3L/TOMM22	2
GO:0060079	excitatory postsynaptic potential	2/319	100/18722	0.51040914399815	0.595429055328148	SNCA/PPP3CA	2
GO:0110020	regulation of actomyosin structure organization	2/319	100/18722	0.51040914399815	0.595429055328148	PTGER4/RGCC	2
GO:0007163	establishment or maintenance of cell polarity	4/319	218/18722	0.510995444383966	0.595943906911343	CCL4/HSP90AB1/HES1/NCKAP1L	4
GO:0006163	purine nucleotide metabolic process	7/319	396/18722	0.514208848910828	0.596151424960717	TMSB4X/DDIT4/HIF1A/PDE4B/LDHA/PGK1/SNCA	7
GO:0019693	ribose phosphate metabolic process	7/319	396/18722	0.514208848910828	0.596151424960717	TMSB4X/DDIT4/HIF1A/PDE4B/LDHA/PGK1/SNCA	7
GO:0000413	protein peptidyl-prolyl isomerization	1/319	42/18722	0.514508697582249	0.596151424960717	PPIF	1
GO:0007520	myoblast fusion	1/319	42/18722	0.514508697582249	0.596151424960717	CD81	1
GO:0009154	purine ribonucleotide catabolic process	1/319	42/18722	0.514508697582249	0.596151424960717	PDE4B	1
GO:0010591	regulation of lamellipodium assembly	1/319	42/18722	0.514508697582249	0.596151424960717	BRK1	1
GO:0014912	negative regulation of smooth muscle cell migration	1/319	42/18722	0.514508697582249	0.596151424960717	TRIB1	1
GO:0019432	triglyceride biosynthetic process	1/319	42/18722	0.514508697582249	0.596151424960717	C3	1
GO:0019692	deoxyribose phosphate metabolic process	1/319	42/18722	0.514508697582249	0.596151424960717	TYMP	1
GO:0021575	hindbrain morphogenesis	1/319	42/18722	0.514508697582249	0.596151424960717	HES1	1
GO:0032965	regulation of collagen biosynthetic process	1/319	42/18722	0.514508697582249	0.596151424960717	RGCC	1
GO:0042168	heme metabolic process	1/319	42/18722	0.514508697582249	0.596151424960717	HMOX1	1
GO:0043507	positive regulation of JUN kinase activity	1/319	42/18722	0.514508697582249	0.596151424960717	TNF	1
GO:0045292	mRNA cis splicing, via spliceosome	1/319	42/18722	0.514508697582249	0.596151424960717	RNU11	1
GO:0055090	acylglycerol homeostasis	1/319	42/18722	0.514508697582249	0.596151424960717	APOE	1
GO:0060999	positive regulation of dendritic spine development	1/319	42/18722	0.514508697582249	0.596151424960717	APOE	1
GO:0070328	triglyceride homeostasis	1/319	42/18722	0.514508697582249	0.596151424960717	APOE	1
GO:0071312	cellular response to alkaloid	1/319	42/18722	0.514508697582249	0.596151424960717	ICAM1	1
GO:0072595	maintenance of protein localization in organelle	1/319	42/18722	0.514508697582249	0.596151424960717	HNRNPU	1
GO:1900274	regulation of phospholipase C activity	1/319	42/18722	0.514508697582249	0.596151424960717	C5AR1	1
GO:1902100	negative regulation of metaphase/anaphase transition of cell cycle	1/319	42/18722	0.514508697582249	0.596151424960717	DUSP1	1
GO:2000404	regulation of T cell migration	1/319	42/18722	0.514508697582249	0.596151424960717	CCL20	1
GO:2001222	regulation of neuron migration	1/319	42/18722	0.514508697582249	0.596151424960717	PHACTR1	1
GO:0006475	internal protein amino acid acetylation	3/319	160/18722	0.515038453090858	0.596429036804652	IL1B/SNCA/SET	3
GO:0060402	calcium ion transport into cytosol	3/319	160/18722	0.515038453090858	0.596429036804652	CCL3/PRNP/SNCA	3
GO:0006476	protein deacetylation	2/319	101/18722	0.515721491274633	0.596883741731424	VEGFA/BCL6	2
GO:0051963	regulation of synapse assembly	2/319	101/18722	0.515721491274633	0.596883741731424	SNCA/SEMA4D	2
GO:0010522	regulation of calcium ion transport into cytosol	2/319	102/18722	0.520995621374748	0.602024829818749	PRNP/SNCA	2
GO:0014897	striated muscle hypertrophy	2/319	102/18722	0.520995621374748	0.602024829818749	NR4A3/PPP3CA	2
GO:0001504	neurotransmitter uptake	1/319	43/18722	0.52279947517707	0.602024829818749	SNCA	1
GO:0006284	base-excision repair	1/319	43/18722	0.52279947517707	0.602024829818749	HMGB1	1
GO:0010171	body morphogenesis	1/319	43/18722	0.52279947517707	0.602024829818749	CSRNP1	1
GO:0021983	pituitary gland development	1/319	43/18722	0.52279947517707	0.602024829818749	HES1	1
GO:0030517	negative regulation of axon extension	1/319	43/18722	0.52279947517707	0.602024829818749	SEMA4D	1
GO:0031952	regulation of protein autophosphorylation	1/319	43/18722	0.52279947517707	0.602024829818749	VEGFA	1
GO:0033046	negative regulation of sister chromatid segregation	1/319	43/18722	0.52279947517707	0.602024829818749	DUSP1	1
GO:0033048	negative regulation of mitotic sister chromatid segregation	1/319	43/18722	0.52279947517707	0.602024829818749	DUSP1	1
GO:0042181	ketone biosynthetic process	1/319	43/18722	0.52279947517707	0.602024829818749	EGR1	1
GO:0045776	negative regulation of blood pressure	1/319	43/18722	0.52279947517707	0.602024829818749	SOD2	1
GO:0046717	acid secretion	1/319	43/18722	0.52279947517707	0.602024829818749	SGK1	1
GO:0061383	trabecula morphogenesis	1/319	43/18722	0.52279947517707	0.602024829818749	SEMA4D	1
GO:0098927	vesicle-mediated transport between endosomal compartments	1/319	43/18722	0.52279947517707	0.602024829818749	SNX3	1
GO:0120178	steroid hormone biosynthetic process	1/319	43/18722	0.52279947517707	0.602024829818749	EGR1	1
GO:1901381	positive regulation of potassium ion transmembrane transport	1/319	43/18722	0.52279947517707	0.602024829818749	ATP1B3	1
GO:2000816	negative regulation of mitotic sister chromatid separation	1/319	43/18722	0.52279947517707	0.602024829818749	DUSP1	1
GO:0019395	fatty acid oxidation	2/319	103/18722	0.526231291062768	0.605637412530526	IRS2/NR4A3	2
GO:0030004	cellular monovalent inorganic cation homeostasis	2/319	103/18722	0.526231291062768	0.605637412530526	ATP1B3/IL1A	2
GO:0006633	fatty acid biosynthetic process	3/319	163/18722	0.527530604744583	0.606793037522379	IL1B/PTGS2/APOC1	3
GO:0061025	membrane fusion	3/319	163/18722	0.527530604744583	0.606793037522379	CHMP2B/STX11/SNCA	3
GO:0005978	glycogen biosynthetic process	1/319	44/18722	0.530949106710798	0.608551990052377	IRS2	1
GO:0006378	mRNA polyadenylation	1/319	44/18722	0.530949106710798	0.608551990052377	YTHDC1	1
GO:0006775	fat-soluble vitamin metabolic process	1/319	44/18722	0.530949106710798	0.608551990052377	TNF	1
GO:0009250	glucan biosynthetic process	1/319	44/18722	0.530949106710798	0.608551990052377	IRS2	1
GO:0009262	deoxyribonucleotide metabolic process	1/319	44/18722	0.530949106710798	0.608551990052377	TYMP	1
GO:0042554	superoxide anion generation	1/319	44/18722	0.530949106710798	0.608551990052377	NCF2	1
GO:0048806	genitalia development	1/319	44/18722	0.530949106710798	0.608551990052377	CTNNB1	1
GO:0060324	face development	1/319	44/18722	0.530949106710798	0.608551990052377	CSRNP1	1
GO:0062208	positive regulation of pattern recognition receptor signaling pathway	1/319	44/18722	0.530949106710798	0.608551990052377	HMGB1	1
GO:0097178	ruffle assembly	1/319	44/18722	0.530949106710798	0.608551990052377	ICAM1	1
GO:1903214	regulation of protein targeting to mitochondrion	1/319	44/18722	0.530949106710798	0.608551990052377	BNIP3L	1
GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	2/319	104/18722	0.531428276401857	0.608551990052377	C5AR1/FPR3	2
GO:0014896	muscle hypertrophy	2/319	104/18722	0.531428276401857	0.608551990052377	NR4A3/PPP3CA	2
GO:0022600	digestive system process	2/319	104/18722	0.531428276401857	0.608551990052377	SGK1/TYMP	2
GO:0032963	collagen metabolic process	2/319	104/18722	0.531428276401857	0.608551990052377	HIF1A/RGCC	2
GO:0060419	heart growth	2/319	104/18722	0.531428276401857	0.608551990052377	PIM1/BASP1	2
GO:0015850	organic hydroxy compound transport	5/319	284/18722	0.533270538450053	0.610491557663093	NFKBIA/SNCA/SPP1/APOE/APOC1	5
GO:0008037	cell recognition	4/319	225/18722	0.535858282849002	0.61328324075508	CXCR4/VDAC2/CD81/FCN1	4
GO:0000041	transition metal ion transport	2/319	105/18722	0.536586372170868	0.613587512988129	SLC25A37/FTH1	2
GO:0016079	synaptic vesicle exocytosis	2/319	105/18722	0.536586372170868	0.613587512988129	STX11/SNCA	2
GO:0003009	skeletal muscle contraction	1/319	45/18722	0.538959987691592	0.613587512988129	NR4A1	1
GO:0030850	prostate gland development	1/319	45/18722	0.538959987691592	0.613587512988129	CTNNB1	1
GO:0032309	icosanoid secretion	1/319	45/18722	0.538959987691592	0.613587512988129	IL1B	1
GO:0035272	exocrine system development	1/319	45/18722	0.538959987691592	0.613587512988129	TNF	1
GO:0035384	thioester biosynthetic process	1/319	45/18722	0.538959987691592	0.613587512988129	SNCA	1
GO:0043631	RNA polyadenylation	1/319	45/18722	0.538959987691592	0.613587512988129	YTHDC1	1
GO:0045910	negative regulation of DNA recombination	1/319	45/18722	0.538959987691592	0.613587512988129	BCL6	1
GO:0045933	positive regulation of muscle contraction	1/319	45/18722	0.538959987691592	0.613587512988129	PTGS2	1
GO:0051180	vitamin transport	1/319	45/18722	0.538959987691592	0.613587512988129	SLC2A3	1
GO:0051985	negative regulation of chromosome segregation	1/319	45/18722	0.538959987691592	0.613587512988129	DUSP1	1
GO:0060119	inner ear receptor cell development	1/319	45/18722	0.538959987691592	0.613587512988129	HES1	1
GO:0071354	cellular response to interleukin-6	1/319	45/18722	0.538959987691592	0.613587512988129	ICAM1	1
GO:0071616	acyl-CoA biosynthetic process	1/319	45/18722	0.538959987691592	0.613587512988129	SNCA	1
GO:0085029	extracellular matrix assembly	1/319	45/18722	0.538959987691592	0.613587512988129	RGCC	1
GO:0098534	centriole assembly	1/319	45/18722	0.538959987691592	0.613587512988129	NPM1	1
GO:1901985	positive regulation of protein acetylation	1/319	45/18722	0.538959987691592	0.613587512988129	IL1B	1
GO:1905819	negative regulation of chromosome separation	1/319	45/18722	0.538959987691592	0.613587512988129	DUSP1	1
GO:0007059	chromosome segregation	6/319	346/18722	0.5399876119681	0.614587229457602	DUSP1/CHMP1B/CHMP2B/CHMP5/CTNNB1/HNRNPU	6
GO:0006766	vitamin metabolic process	2/319	106/18722	0.541705391295322	0.616201124409261	TNF/SLC2A3	2
GO:0099565	chemical synaptic transmission, postsynaptic	2/319	106/18722	0.541705391295322	0.616201124409261	SNCA/PPP3CA	2
GO:0046777	protein autophosphorylation	4/319	227/18722	0.542846062645063	0.617327846067456	PIM3/VEGFA/PIM1/STK17B	4
GO:0000018	regulation of DNA recombination	2/319	107/18722	0.546785164292226	0.619976977083252	BCL6/STAT6	2
GO:0005976	polysaccharide metabolic process	2/319	107/18722	0.546785164292226	0.619976977083252	IRS2/HMGB1	2
GO:0032526	response to retinoic acid	2/319	107/18722	0.546785164292226	0.619976977083252	KLF4/DUSP1	2
GO:0006195	purine nucleotide catabolic process	1/319	46/18722	0.546834473097512	0.619976977083252	PDE4B	1
GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	1/319	46/18722	0.546834473097512	0.619976977083252	ICAM1	1
GO:0031018	endocrine pancreas development	1/319	46/18722	0.546834473097512	0.619976977083252	HES1	1
GO:0050919	negative chemotaxis	1/319	46/18722	0.546834473097512	0.619976977083252	SEMA4D	1
GO:0060976	coronary vasculature development	1/319	46/18722	0.546834473097512	0.619976977083252	VEGFA	1
GO:0061462	protein localization to lysosome	1/319	46/18722	0.546834473097512	0.619976977083252	CD81	1
GO:0090329	regulation of DNA-dependent DNA replication	1/319	46/18722	0.546834473097512	0.619976977083252	BCL6	1
GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	1/319	46/18722	0.546834473097512	0.619976977083252	RGCC	1
GO:0034440	lipid oxidation	2/319	108/18722	0.551825538728451	0.624594159863499	IRS2/NR4A3	2
GO:0098659	inorganic cation import across plasma membrane	2/319	108/18722	0.551825538728451	0.624594159863499	ATP1B3/PRNP	2
GO:0099587	inorganic ion import across plasma membrane	2/319	108/18722	0.551825538728451	0.624594159863499	ATP1B3/PRNP	2
GO:0140053	mitochondrial gene expression	2/319	108/18722	0.551825538728451	0.624594159863499	MRPS21/MRPL52	2
GO:0000075	cell cycle checkpoint signaling	3/319	169/18722	0.551970465284381	0.624594159863499	DUSP1/CDKN1A/SYF2	3
GO:0006937	regulation of muscle contraction	3/319	169/18722	0.551970465284381	0.624594159863499	NR4A1/PDE4B/PTGS2	3
GO:0018394	peptidyl-lysine acetylation	3/319	169/18722	0.551970465284381	0.624594159863499	IL1B/SNCA/SET	3
GO:0001754	eye photoreceptor cell differentiation	1/319	47/18722	0.554574878060133	0.625475260275776	VEGFA	1
GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal	1/319	47/18722	0.554574878060133	0.625475260275776	SOD2	1
GO:0009261	ribonucleotide catabolic process	1/319	47/18722	0.554574878060133	0.625475260275776	PDE4B	1
GO:0010712	regulation of collagen metabolic process	1/319	47/18722	0.554574878060133	0.625475260275776	RGCC	1
GO:0010761	fibroblast migration	1/319	47/18722	0.554574878060133	0.625475260275776	THBS1	1
GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	1/319	47/18722	0.554574878060133	0.625475260275776	TNFAIP3	1
GO:0014911	positive regulation of smooth muscle cell migration	1/319	47/18722	0.554574878060133	0.625475260275776	NR4A3	1
GO:0032008	positive regulation of TOR signaling	1/319	47/18722	0.554574878060133	0.625475260275776	NCKAP1L	1
GO:0045911	positive regulation of DNA recombination	1/319	47/18722	0.554574878060133	0.625475260275776	STAT6	1
GO:0101023	vascular endothelial cell proliferation	1/319	47/18722	0.554574878060133	0.625475260275776	HMGB1	1
GO:0120163	negative regulation of cold-induced thermogenesis	1/319	47/18722	0.554574878060133	0.625475260275776	TLE3	1
GO:1905562	regulation of vascular endothelial cell proliferation	1/319	47/18722	0.554574878060133	0.625475260275776	HMGB1	1
GO:0030178	negative regulation of Wnt signaling pathway	3/319	170/18722	0.555970830714068	0.62687769749466	TLE3/EGR1/APOE	3
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	7/319	412/18722	0.556239330571988	0.627008469421838	TRIB1/GABARAP/CTNNB1/HSP90AB1/SUMO2/RNF19B/PIAS1	7
GO:0032410	negative regulation of transporter activity	2/319	109/18722	0.556826378692361	0.627326183284269	PPIF/SNCA	2
GO:0043266	regulation of potassium ion transport	2/319	109/18722	0.556826378692361	0.627326183284269	ATP1B3/PRNP	2
GO:0001822	kidney development	5/319	293/18722	0.561029869783531	0.631458000072168	VEGFA/CTNNB1/BASP1/EGR1/HES1	5
GO:0014812	muscle cell migration	2/319	110/18722	0.561787564278395	0.631458000072168	TRIB1/NR4A3	2
GO:0018958	phenol-containing compound metabolic process	2/319	110/18722	0.561787564278395	0.631458000072168	NR4A2/SNCA	2
GO:0030317	flagellated sperm motility	2/319	110/18722	0.561787564278395	0.631458000072168	DNAJA1/DEFB1	2
GO:0097722	sperm motility	2/319	110/18722	0.561787564278395	0.631458000072168	DNAJA1/DEFB1	2
GO:0032527	protein exit from endoplasmic reticulum	1/319	48/18722	0.562183478536642	0.631458000072168	CD81	1
GO:0033628	regulation of cell adhesion mediated by integrin	1/319	48/18722	0.562183478536642	0.631458000072168	NCKAP1L	1
GO:0035036	sperm-egg recognition	1/319	48/18722	0.562183478536642	0.631458000072168	VDAC2	1
GO:0045839	negative regulation of mitotic nuclear division	1/319	48/18722	0.562183478536642	0.631458000072168	DUSP1	1
GO:0120009	intermembrane lipid transfer	1/319	48/18722	0.562183478536642	0.631458000072168	APOE	1
GO:1903053	regulation of extracellular matrix organization	1/319	48/18722	0.562183478536642	0.631458000072168	RGCC	1
GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	4/319	233/18722	0.563480982601855	0.63274250736854	PDE4B/RGS1/PTGER4/PF4	4
GO:0051604	protein maturation	5/319	294/18722	0.564063527060541	0.633223691902207	PGK1/PRNP/SRGN/RIPK2/THBS1	5
GO:0072521	purine-containing compound metabolic process	7/319	416/18722	0.566500749109254	0.635786126013689	TMSB4X/DDIT4/HIF1A/PDE4B/LDHA/PGK1/SNCA	7
GO:0000910	cytokinesis	3/319	173/18722	0.56784331112778	0.636381137693308	CHMP1B/CHMP2B/CHMP5	3
GO:0006694	steroid biosynthetic process	3/319	173/18722	0.56784331112778	0.636381137693308	TNF/EGR1/APOE	3
GO:0006778	porphyrin-containing compound metabolic process	1/319	49/18722	0.569662511970658	0.636381137693308	HMOX1	1
GO:0008038	neuron recognition	1/319	49/18722	0.569662511970658	0.636381137693308	CXCR4	1
GO:0009395	phospholipid catabolic process	1/319	49/18722	0.569662511970658	0.636381137693308	APOC1	1
GO:0010823	negative regulation of mitochondrion organization	1/319	49/18722	0.569662511970658	0.636381137693308	PPIF	1
GO:0038084	vascular endothelial growth factor signaling pathway	1/319	49/18722	0.569662511970658	0.636381137693308	VEGFA	1
GO:0042461	photoreceptor cell development	1/319	49/18722	0.569662511970658	0.636381137693308	VEGFA	1
GO:0045778	positive regulation of ossification	1/319	49/18722	0.569662511970658	0.636381137693308	ISG15	1
GO:0046580	negative regulation of Ras protein signal transduction	1/319	49/18722	0.569662511970658	0.636381137693308	BCL6	1
GO:0051445	regulation of meiotic cell cycle	1/319	49/18722	0.569662511970658	0.636381137693308	DUSP1	1
GO:0070741	response to interleukin-6	1/319	49/18722	0.569662511970658	0.636381137693308	ICAM1	1
GO:0072666	establishment of protein localization to vacuole	1/319	49/18722	0.569662511970658	0.636381137693308	TNFAIP3	1
GO:0086009	membrane repolarization	1/319	49/18722	0.569662511970658	0.636381137693308	ATP1B3	1
GO:1901799	negative regulation of proteasomal protein catabolic process	1/319	49/18722	0.569662511970658	0.636381137693308	HSP90AB1	1
GO:1904752	regulation of vascular associated smooth muscle cell migration	1/319	49/18722	0.569662511970658	0.636381137693308	NR4A3	1
GO:1990573	potassium ion import across plasma membrane	1/319	49/18722	0.569662511970658	0.636381137693308	ATP1B3	1
GO:0035601	protein deacylation	2/319	112/18722	0.571590569720932	0.638361540918976	VEGFA/BCL6	2
GO:0002639	positive regulation of immunoglobulin production	1/319	50/18722	0.577014177941919	0.642150862349548	STAT6	1
GO:0006220	pyrimidine nucleotide metabolic process	1/319	50/18722	0.577014177941919	0.642150862349548	TYMP	1
GO:0015872	dopamine transport	1/319	50/18722	0.577014177941919	0.642150862349548	SNCA	1
GO:0038093	Fc receptor signaling pathway	1/319	50/18722	0.577014177941919	0.642150862349548	NR4A3	1
GO:0043268	positive regulation of potassium ion transport	1/319	50/18722	0.577014177941919	0.642150862349548	ATP1B3	1
GO:0043628	ncRNA 3'-end processing	1/319	50/18722	0.577014177941919	0.642150862349548	SSB	1
GO:0045058	T cell selection	1/319	50/18722	0.577014177941919	0.642150862349548	STAT6	1
GO:0046460	neutral lipid biosynthetic process	1/319	50/18722	0.577014177941919	0.642150862349548	C3	1
GO:0046463	acylglycerol biosynthetic process	1/319	50/18722	0.577014177941919	0.642150862349548	C3	1
GO:0051646	mitochondrion localization	1/319	50/18722	0.577014177941919	0.642150862349548	HIF1A	1
GO:0090102	cochlea development	1/319	50/18722	0.577014177941919	0.642150862349548	HES1	1
GO:0099054	presynapse assembly	1/319	50/18722	0.577014177941919	0.642150862349548	SNCA	1
GO:1904738	vascular associated smooth muscle cell migration	1/319	50/18722	0.577014177941919	0.642150862349548	NR4A3	1
GO:0007041	lysosomal transport	2/319	114/18722	0.581233897136674	0.646496902361706	CHMP2B/CHMP5	2
GO:0019751	polyol metabolic process	2/319	114/18722	0.581233897136674	0.646496902361706	SNCA/PLEK	2
GO:0010656	negative regulation of muscle cell apoptotic process	1/319	51/18722	0.584240638805058	0.648788024345649	HMOX1	1
GO:0032964	collagen biosynthetic process	1/319	51/18722	0.584240638805058	0.648788024345649	RGCC	1
GO:0043124	negative regulation of I-kappaB kinase/NF-kappaB signaling	1/319	51/18722	0.584240638805058	0.648788024345649	TNFAIP3	1
GO:0045104	intermediate filament cytoskeleton organization	1/319	51/18722	0.584240638805058	0.648788024345649	DNAJB6	1
GO:0060043	regulation of cardiac muscle cell proliferation	1/319	51/18722	0.584240638805058	0.648788024345649	PIM1	1
GO:0060632	regulation of microtubule-based movement	1/319	51/18722	0.584240638805058	0.648788024345649	DEFB1	1
GO:0000077	DNA damage checkpoint signaling	2/319	115/18722	0.58599553795726	0.650209893803589	CDKN1A/SYF2	2
GO:0051209	release of sequestered calcium ion into cytosol	2/319	115/18722	0.58599553795726	0.650209893803589	CCL3/SNCA	2
GO:1901989	positive regulation of cell cycle phase transition	2/319	115/18722	0.58599553795726	0.650209893803589	NPM1/RGCC	2
GO:0072001	renal system development	5/319	302/18722	0.587943909456669	0.65219573982093	VEGFA/CTNNB1/BASP1/EGR1/HES1	5
GO:0018107	peptidyl-threonine phosphorylation	2/319	116/18722	0.59071711379317	0.653850260227479	DDIT4/RIPK2	2
GO:0030326	embryonic limb morphogenesis	2/319	116/18722	0.59071711379317	0.653850260227479	CTNNB1/TMEM107	2
GO:0031123	RNA 3'-end processing	2/319	116/18722	0.59071711379317	0.653850260227479	YTHDC1/SSB	2
GO:0033559	unsaturated fatty acid metabolic process	2/319	116/18722	0.59071711379317	0.653850260227479	IL1B/PTGS2	2
GO:0035113	embryonic appendage morphogenesis	2/319	116/18722	0.59071711379317	0.653850260227479	CTNNB1/TMEM107	2
GO:0051283	negative regulation of sequestering of calcium ion	2/319	116/18722	0.59071711379317	0.653850260227479	CCL3/SNCA	2
GO:0098732	macromolecule deacylation	2/319	116/18722	0.59071711379317	0.653850260227479	VEGFA/BCL6	2
GO:0006941	striated muscle contraction	3/319	179/18722	0.590996017716596	0.653850260227479	CXCR4/NR4A1/PDE4B	3
GO:0045010	actin nucleation	1/319	52/18722	0.591344020317628	0.653850260227479	BRK1	1
GO:0045103	intermediate filament-based process	1/319	52/18722	0.591344020317628	0.653850260227479	DNAJB6	1
GO:0051496	positive regulation of stress fiber assembly	1/319	52/18722	0.591344020317628	0.653850260227479	RGCC	1
GO:0072523	purine-containing compound catabolic process	1/319	52/18722	0.591344020317628	0.653850260227479	PDE4B	1
GO:0015698	inorganic anion transport	3/319	180/18722	0.594776497595827	0.657468723209584	VDAC2/PRNP/CEBPB	3
GO:0014902	myotube differentiation	2/319	117/18722	0.595398603379842	0.657802649420728	CD81/PPP3CA	2
GO:1903828	negative regulation of cellular protein localization	2/319	117/18722	0.595398603379842	0.657802649420728	DNAJA1/GBP1	2
GO:0009117	nucleotide metabolic process	8/319	489/18722	0.596206394489408	0.658518132118742	TMSB4X/DDIT4/HIF1A/PDE4B/LDHA/PGK1/SNCA/TYMP	8
GO:0045806	negative regulation of endocytosis	1/319	53/18722	0.598326412257567	0.660504801501305	APOC1	1
GO:0071715	icosanoid transport	1/319	53/18722	0.598326412257567	0.660504801501305	IL1B	1
GO:0099504	synaptic vesicle cycle	3/319	181/18722	0.598534302448883	0.660556917414056	STX11/CTNNB1/SNCA	3
GO:0030203	glycosaminoglycan metabolic process	2/319	118/18722	0.600039997768929	0.661863276315553	IL1B/PIM1	2
GO:0051282	regulation of sequestering of calcium ion	2/319	118/18722	0.600039997768929	0.661863276315553	CCL3/SNCA	2
GO:0060401	cytosolic calcium ion transport	3/319	182/18722	0.602269332926076	0.664144106131733	CCL3/PRNP/SNCA	3
GO:0017148	negative regulation of translation	4/319	245/18722	0.603175842415269	0.664965376285645	NCL/ZFP36/TOB1/YBX1	4
GO:0007215	glutamate receptor signaling pathway	1/319	54/18722	0.605189869030283	0.665757439546025	PRNP	1
GO:0010524	positive regulation of calcium ion transport into cytosol	1/319	54/18722	0.605189869030283	0.665757439546025	SNCA	1
GO:0014888	striated muscle adaptation	1/319	54/18722	0.605189869030283	0.665757439546025	PPP3CA	1
GO:0030520	intracellular estrogen receptor signaling pathway	1/319	54/18722	0.605189869030283	0.665757439546025	DDX5	1
GO:0030834	regulation of actin filament depolymerization	1/319	54/18722	0.605189869030283	0.665757439546025	PLEK	1
GO:0032330	regulation of chondrocyte differentiation	1/319	54/18722	0.605189869030283	0.665757439546025	CTNNB1	1
GO:0070839	metal ion export	1/319	54/18722	0.605189869030283	0.665757439546025	ATP1B3	1
GO:1902743	regulation of lamellipodium organization	1/319	54/18722	0.605189869030283	0.665757439546025	BRK1	1
GO:2001257	regulation of cation channel activity	3/319	184/18722	0.60967070329284	0.670507293000767	TMSB4X/PDE4B/IFNGR2	3
GO:0000768	syncytium formation by plasma membrane fusion	1/319	55/18722	0.611936410265517	0.671561821303134	CD81	1
GO:0002067	glandular epithelial cell differentiation	1/319	55/18722	0.611936410265517	0.671561821303134	HES1	1
GO:0003229	ventricular cardiac muscle tissue development	1/319	55/18722	0.611936410265517	0.671561821303134	ID2	1
GO:0006360	transcription by RNA polymerase I	1/319	55/18722	0.611936410265517	0.671561821303134	NCL	1
GO:0006414	translational elongation	1/319	55/18722	0.611936410265517	0.671561821303134	EEF1A1	1
GO:0046164	alcohol catabolic process	1/319	55/18722	0.611936410265517	0.671561821303134	APOE	1
GO:0051898	negative regulation of protein kinase B signaling	1/319	55/18722	0.611936410265517	0.671561821303134	KLF4	1
GO:0140253	cell-cell fusion	1/319	55/18722	0.611936410265517	0.671561821303134	CD81	1
GO:0001838	embryonic epithelial tube formation	2/319	121/18722	0.613723696452682	0.672984293442779	HIF1A/CTNNB1	2
GO:0003206	cardiac chamber morphogenesis	2/319	121/18722	0.613723696452682	0.672984293442779	HIF1A/HES1	2
GO:0045931	positive regulation of mitotic cell cycle	2/319	121/18722	0.613723696452682	0.672984293442779	RGCC/HES1	2
GO:0006753	nucleoside phosphate metabolic process	8/319	497/18722	0.614495784108632	0.67365124492549	TMSB4X/DDIT4/HIF1A/PDE4B/LDHA/PGK1/SNCA/TYMP	8
GO:0070588	calcium ion transmembrane transport	5/319	312/18722	0.616768792150726	0.675952455075108	CCL3/PDE4B/PRNP/VMP1/SNCA	5
GO:0031109	microtubule polymerization or depolymerization	2/319	122/18722	0.618204852724681	0.675952455075108	MAPRE1/SNCA	2
GO:0051208	sequestering of calcium ion	2/319	122/18722	0.618204852724681	0.675952455075108	CCL3/SNCA	2
GO:0002090	regulation of receptor internalization	1/319	56/18722	0.618568021404174	0.675952455075108	VEGFA	1
GO:0010518	positive regulation of phospholipase activity	1/319	56/18722	0.618568021404174	0.675952455075108	C5AR1	1
GO:0015800	acidic amino acid transport	1/319	56/18722	0.618568021404174	0.675952455075108	SNCA	1
GO:0030166	proteoglycan biosynthetic process	1/319	56/18722	0.618568021404174	0.675952455075108	CTNNB1	1
GO:0045599	negative regulation of fat cell differentiation	1/319	56/18722	0.618568021404174	0.675952455075108	TNF	1
GO:0050433	regulation of catecholamine secretion	1/319	56/18722	0.618568021404174	0.675952455075108	SNCA	1
GO:0051058	negative regulation of small GTPase mediated signal transduction	1/319	56/18722	0.618568021404174	0.675952455075108	BCL6	1
GO:0051784	negative regulation of nuclear division	1/319	56/18722	0.618568021404174	0.675952455075108	DUSP1	1
GO:0098781	ncRNA transcription	1/319	56/18722	0.618568021404174	0.675952455075108	NCL	1
GO:0006605	protein targeting	5/319	314/18722	0.622390463951571	0.679686104491174	BNIP3L/GABARAP/TOMM22/PRNP/NACA	5
GO:0003231	cardiac ventricle development	2/319	123/18722	0.622646039774693	0.679686104491174	HIF1A/HES1	2
GO:0006690	icosanoid metabolic process	2/319	123/18722	0.622646039774693	0.679686104491174	IL1B/PTGS2	2
GO:0031570	DNA integrity checkpoint signaling	2/319	123/18722	0.622646039774693	0.679686104491174	CDKN1A/SYF2	2
GO:0002011	morphogenesis of an epithelial sheet	1/319	57/18722	0.62508665427528	0.680723506152497	HBEGF	1
GO:0006695	cholesterol biosynthetic process	1/319	57/18722	0.62508665427528	0.680723506152497	APOE	1
GO:0006754	ATP biosynthetic process	1/319	57/18722	0.62508665427528	0.680723506152497	TMSB4X	1
GO:0006949	syncytium formation	1/319	57/18722	0.62508665427528	0.680723506152497	CD81	1
GO:0050879	multicellular organismal movement	1/319	57/18722	0.62508665427528	0.680723506152497	NR4A1	1
GO:0050881	musculoskeletal movement	1/319	57/18722	0.62508665427528	0.680723506152497	NR4A1	1
GO:0051205	protein insertion into membrane	1/319	57/18722	0.62508665427528	0.680723506152497	TOMM22	1
GO:0051289	protein homotetramerization	1/319	57/18722	0.62508665427528	0.680723506152497	SOD2	1
GO:1902653	secondary alcohol biosynthetic process	1/319	57/18722	0.62508665427528	0.680723506152497	APOE	1
GO:0007368	determination of left/right symmetry	2/319	124/18722	0.62704731427594	0.682677836066841	HIF1A/TMEM107	2
GO:0046578	regulation of Ras protein signal transduction	3/319	189/18722	0.627769753337187	0.683283414341853	GABARAP/BCL6/APOE	3
GO:0043414	macromolecule methylation	5/319	316/18722	0.627963058602737	0.683312899395408	FOS/ETF1/CTNNB1/BTG1/PRMT9	5
GO:0018210	peptidyl-threonine modification	2/319	125/18722	0.631408742550642	0.685703320106592	DDIT4/RIPK2	2
GO:0060294	cilium movement involved in cell motility	2/319	125/18722	0.631408742550642	0.685703320106592	DNAJA1/DEFB1	2
GO:0018208	peptidyl-proline modification	1/319	58/18722	0.631494227663235	0.685703320106592	PPIF	1
GO:0032387	negative regulation of intracellular transport	1/319	58/18722	0.631494227663235	0.685703320106592	SNX3	1
GO:0035904	aorta development	1/319	58/18722	0.631494227663235	0.685703320106592	HES1	1
GO:0050432	catecholamine secretion	1/319	58/18722	0.631494227663235	0.685703320106592	SNCA	1
GO:1902808	positive regulation of cell cycle G1/S phase transition	1/319	58/18722	0.631494227663235	0.685703320106592	RGCC	1
GO:2000649	regulation of sodium ion transmembrane transporter activity	1/319	58/18722	0.631494227663235	0.685703320106592	YWHAH	1
GO:0090596	sensory organ morphogenesis	4/319	256/18722	0.637588012881747	0.691264300858199	HIF1A/VEGFA/CTNNB1/HMGN1	4
GO:1903522	regulation of blood circulation	4/319	256/18722	0.637588012881747	0.691264300858199	ICAM1/PDE4B/HBEGF/PTGS2	4
GO:0006767	water-soluble vitamin metabolic process	1/319	59/18722	0.637792627865519	0.691264300858199	SLC2A3	1
GO:0019369	arachidonic acid metabolic process	1/319	59/18722	0.637792627865519	0.691264300858199	PTGS2	1
GO:0030042	actin filament depolymerization	1/319	59/18722	0.637792627865519	0.691264300858199	PLEK	1
GO:0033013	tetrapyrrole metabolic process	1/319	59/18722	0.637792627865519	0.691264300858199	HMOX1	1
GO:0051568	histone H3-K4 methylation	1/319	59/18722	0.637792627865519	0.691264300858199	CTNNB1	1
GO:0008033	tRNA processing	2/319	127/18722	0.640012371903973	0.693487311781031	LSM6/SSB	2
GO:0006893	Golgi to plasma membrane transport	1/319	60/18722	0.643983709241016	0.696505400865513	VAMP5	1
GO:0030071	regulation of mitotic metaphase/anaphase transition	1/319	60/18722	0.643983709241016	0.696505400865513	DUSP1	1
GO:0033866	nucleoside bisphosphate biosynthetic process	1/319	60/18722	0.643983709241016	0.696505400865513	SNCA	1
GO:0034030	ribonucleoside bisphosphate biosynthetic process	1/319	60/18722	0.643983709241016	0.696505400865513	SNCA	1
GO:0034033	purine nucleoside bisphosphate biosynthetic process	1/319	60/18722	0.643983709241016	0.696505400865513	SNCA	1
GO:0051965	positive regulation of synapse assembly	1/319	60/18722	0.643983709241016	0.696505400865513	SEMA4D	1
GO:0060038	cardiac muscle cell proliferation	1/319	60/18722	0.643983709241016	0.696505400865513	PIM1	1
GO:0006022	aminoglycan metabolic process	2/319	129/18722	0.648457638570474	0.701159745440089	IL1B/PIM1	2
GO:0040014	regulation of multicellular organism growth	1/319	61/18722	0.650069294749113	0.702532826160254	PLAC8	1
GO:0060998	regulation of dendritic spine development	1/319	61/18722	0.650069294749113	0.702532826160254	APOE	1
GO:0031032	actomyosin structure organization	3/319	196/18722	0.65212645981412	0.704570795347135	PHACTR1/PTGER4/RGCC	3
GO:0006282	regulation of DNA repair	2/319	130/18722	0.652621144726542	0.704734837397114	DEK/HMGB1	2
GO:0030534	adult behavior	2/319	130/18722	0.652621144726542	0.704734837397114	NR4A2/SNCA	2
GO:0007062	sister chromatid cohesion	1/319	62/18722	0.65605117647973	0.706582757796219	CTNNB1	1
GO:0007091	metaphase/anaphase transition of mitotic cell cycle	1/319	62/18722	0.65605117647973	0.706582757796219	DUSP1	1
GO:0007588	excretion	1/319	62/18722	0.65605117647973	0.706582757796219	HMOX1	1
GO:0009116	nucleoside metabolic process	1/319	62/18722	0.65605117647973	0.706582757796219	TYMP	1
GO:0019933	cAMP-mediated signaling	1/319	62/18722	0.65605117647973	0.706582757796219	DEFB1	1
GO:0031124	mRNA 3'-end processing	1/319	62/18722	0.65605117647973	0.706582757796219	YTHDC1	1
GO:0048488	synaptic vesicle endocytosis	1/319	62/18722	0.65605117647973	0.706582757796219	SNCA	1
GO:0048663	neuron fate commitment	1/319	62/18722	0.65605117647973	0.706582757796219	ID2	1
GO:0060113	inner ear receptor cell differentiation	1/319	62/18722	0.65605117647973	0.706582757796219	HES1	1
GO:0140238	presynaptic endocytosis	1/319	62/18722	0.65605117647973	0.706582757796219	SNCA	1
GO:0006612	protein targeting to membrane	2/319	131/18722	0.65674538660697	0.706960011610697	PRNP/NACA	2
GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	2/319	131/18722	0.65674538660697	0.706960011610697	SKIL/TOB1	2
GO:0030111	regulation of Wnt signaling pathway	5/319	328/18722	0.660342534491777	0.710646114998873	TNFAIP3/SNX3/TLE3/EGR1/APOE	5
GO:0035264	multicellular organism growth	2/319	132/18722	0.66083048894851	0.710732451153626	KLF2/PLAC8	2
GO:0072175	epithelial tube formation	2/319	132/18722	0.66083048894851	0.710732451153626	HIF1A/CTNNB1	2
GO:0046486	glycerolipid metabolic process	6/319	392/18722	0.660941415898884	0.710732451153626	SOCS3/PLEK/APOE/C3/DGKZ/APOC1	6
GO:0001947	heart looping	1/319	63/18722	0.661931116174423	0.711052735456768	HIF1A	1
GO:0099601	regulation of neurotransmitter receptor activity	1/319	63/18722	0.661931116174423	0.711052735456768	IFNGR2	1
GO:1902099	regulation of metaphase/anaphase transition of cell cycle	1/319	63/18722	0.661931116174423	0.711052735456768	DUSP1	1
GO:2000242	negative regulation of reproductive process	1/319	63/18722	0.661931116174423	0.711052735456768	DUSP1	1
GO:0099003	vesicle-mediated transport in synapse	3/319	200/18722	0.665526022545944	0.71472765900898	STX11/CTNNB1/SNCA	3
GO:0006940	regulation of smooth muscle contraction	1/319	64/18722	0.667710845738727	0.716138608617769	PTGS2	1
GO:0016126	sterol biosynthetic process	1/319	64/18722	0.667710845738727	0.716138608617769	APOE	1
GO:0046530	photoreceptor cell differentiation	1/319	64/18722	0.667710845738727	0.716138608617769	VEGFA	1
GO:0046854	phosphatidylinositol phosphate biosynthetic process	1/319	64/18722	0.667710845738727	0.716138608617769	SOCS3	1
GO:0098930	axonal transport	1/319	64/18722	0.667710845738727	0.716138608617769	HIF1A	1
GO:0006473	protein acetylation	3/319	201/18722	0.668816827938566	0.717137709873616	IL1B/SNCA/SET	3
GO:0017157	regulation of exocytosis	3/319	202/18722	0.672083995683426	0.720453013364945	SNCA/HMOX1/NCKAP1L	3
GO:0009581	detection of external stimulus	2/319	135/18722	0.672852311545205	0.720540028761918	CXCR4/CTNNB1	2
GO:0006487	protein N-linked glycosylation	1/319	65/18722	0.673392067745874	0.720540028761918	DAD1	1
GO:0010965	regulation of mitotic sister chromatid separation	1/319	65/18722	0.673392067745874	0.720540028761918	DUSP1	1
GO:0033692	cellular polysaccharide biosynthetic process	1/319	65/18722	0.673392067745874	0.720540028761918	IRS2	1
GO:0044784	metaphase/anaphase transition of cell cycle	1/319	65/18722	0.673392067745874	0.720540028761918	DUSP1	1
GO:0046503	glycerolipid catabolic process	1/319	65/18722	0.673392067745874	0.720540028761918	APOC1	1
GO:0061512	protein localization to cilium	1/319	65/18722	0.673392067745874	0.720540028761918	TMEM107	1
GO:0043624	cellular protein complex disassembly	2/319	136/18722	0.676782241771312	0.723790789781962	ETF1/PLEK	2
GO:1903305	regulation of regulated secretory pathway	2/319	136/18722	0.676782241771312	0.723790789781962	HMOX1/NCKAP1L	2
GO:0016570	histone modification	7/319	463/18722	0.677879462785333	0.72477567529532	IL1B/KDM6B/VEGFA/CTNNB1/BCL6/SNCA/SET	7
GO:0071300	cellular response to retinoic acid	1/319	66/18722	0.678976455932027	0.725571149034719	KLF4	1
GO:2000272	negative regulation of signaling receptor activity	1/319	66/18722	0.678976455932027	0.725571149034719	TNF	1
GO:0000086	G2/M transition of mitotic cell cycle	2/319	137/18722	0.680673757791296	0.72625222379445	CDKN1A/SYF2	2
GO:0007266	Rho protein signal transduction	2/319	137/18722	0.680673757791296	0.72625222379445	BCL6/APOE	2
GO:0007586	digestion	2/319	137/18722	0.680673757791296	0.72625222379445	SGK1/TYMP	2
GO:0034754	cellular hormone metabolic process	2/319	137/18722	0.680673757791296	0.72625222379445	EGR1/SPP1	2
GO:0060048	cardiac muscle contraction	2/319	137/18722	0.680673757791296	0.72625222379445	CXCR4/PDE4B	2
GO:0060078	regulation of postsynaptic membrane potential	2/319	137/18722	0.680673757791296	0.72625222379445	SNCA/PPP3CA	2
GO:0042490	mechanoreceptor differentiation	1/319	67/18722	0.68446565568319	0.72847284291949	HES1	1
GO:0051306	mitotic sister chromatid separation	1/319	67/18722	0.68446565568319	0.72847284291949	DUSP1	1
GO:0061077	chaperone-mediated protein folding	1/319	67/18722	0.68446565568319	0.72847284291949	DNAJB6	1
GO:0061371	determination of heart left/right asymmetry	1/319	67/18722	0.68446565568319	0.72847284291949	HIF1A	1
GO:1902117	positive regulation of organelle assembly	1/319	67/18722	0.68446565568319	0.72847284291949	TNF	1
GO:0001539	cilium or flagellum-dependent cell motility	2/319	138/18722	0.684527023156893	0.72847284291949	DNAJA1/DEFB1	2
GO:0009582	detection of abiotic stimulus	2/319	138/18722	0.684527023156893	0.72847284291949	CXCR4/CTNNB1	2
GO:0035107	appendage morphogenesis	2/319	138/18722	0.684527023156893	0.72847284291949	CTNNB1/TMEM107	2
GO:0035108	limb morphogenesis	2/319	138/18722	0.684527023156893	0.72847284291949	CTNNB1/TMEM107	2
GO:0060285	cilium-dependent cell motility	2/319	138/18722	0.684527023156893	0.72847284291949	DNAJA1/DEFB1	2
GO:0001655	urogenital system development	5/319	338/18722	0.685903340081416	0.729748610526579	VEGFA/CTNNB1/BASP1/EGR1/HES1	5
GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules	4/319	273/18722	0.686838649349873	0.73055464100319	KLF4/ICAM1/MYADM/IL1RN	4
GO:0007585	respiratory gaseous exchange by respiratory system	1/319	68/18722	0.689861284513909	0.733011046946673	NR4A2	1
GO:0009206	purine ribonucleoside triphosphate biosynthetic process	1/319	68/18722	0.689861284513909	0.733011046946673	TMSB4X	1
GO:0060411	cardiac septum morphogenesis	1/319	68/18722	0.689861284513909	0.733011046946673	HES1	1
GO:1901016	regulation of potassium ion transmembrane transporter activity	1/319	68/18722	0.689861284513909	0.733011046946673	ATP1B3	1
GO:0006836	neurotransmitter transport	3/319	208/18722	0.691191182736674	0.734234354581516	NR4A1/STX11/SNCA	3
GO:0015748	organophosphate ester transport	2/319	140/18722	0.69211948379203	0.735030534195049	APOE/APOC1	2
GO:0009145	purine nucleoside triphosphate biosynthetic process	1/319	69/18722	0.695164932537928	0.737312445217601	TMSB4X	1
GO:0019226	transmission of nerve impulse	1/319	69/18722	0.695164932537928	0.737312445217601	TYMP	1
GO:0031060	regulation of histone methylation	1/319	69/18722	0.695164932537928	0.737312445217601	CTNNB1	1
GO:0045665	negative regulation of neuron differentiation	1/319	69/18722	0.695164932537928	0.737312445217601	HES1	1
GO:0060193	positive regulation of lipase activity	1/319	69/18722	0.695164932537928	0.737312445217601	C5AR1	1
GO:0007009	plasma membrane organization	2/319	142/18722	0.699561039467736	0.741783707312835	CXCR4/SERP1	2
GO:0070830	bicellular tight junction assembly	1/319	70/18722	0.700378162930916	0.742458645644403	TNF	1
GO:0030010	establishment of cell polarity	2/319	143/18722	0.703225691975518	0.7452850785541	HSP90AB1/HES1	2
GO:0003208	cardiac ventricle morphogenesis	1/319	71/18722	0.7055025123854	0.747312761766653	HIF1A	1
GO:0003281	ventricular septum development	1/319	71/18722	0.7055025123854	0.747312761766653	HES1	1
GO:0001505	regulation of neurotransmitter levels	3/319	213/18722	0.706466993260331	0.748141630420717	NR4A1/STX11/SNCA	3
GO:0031644	regulation of nervous system process	2/319	144/18722	0.706853184254734	0.748357826544221	CCL3/TYMP	2
GO:0006936	muscle contraction	5/319	347/18722	0.707776394469565	0.749142316597421	CXCR4/NR4A1/PDE4B/PTGS2/TPM3	5
GO:0072330	monocarboxylic acid biosynthetic process	3/319	214/18722	0.709451991645323	0.750722557954677	IL1B/PTGS2/APOC1	3
GO:0000271	polysaccharide biosynthetic process	1/319	72/18722	0.710539491558048	0.751099987090547	IRS2	1
GO:0030032	lamellipodium assembly	1/319	72/18722	0.710539491558048	0.751099987090547	BRK1	1
GO:0055021	regulation of cardiac muscle tissue growth	1/319	72/18722	0.710539491558048	0.751099987090547	PIM1	1
GO:1905818	regulation of chromosome separation	1/319	72/18722	0.710539491558048	0.751099987090547	DUSP1	1
GO:0045739	positive regulation of DNA repair	1/319	73/18722	0.715490585509415	0.755168625681439	HMGB1	1
GO:0051865	protein autoubiquitination	1/319	73/18722	0.715490585509415	0.755168625681439	RNF19B	1
GO:0051937	catecholamine transport	1/319	73/18722	0.715490585509415	0.755168625681439	SNCA	1
GO:0061035	regulation of cartilage development	1/319	73/18722	0.715490585509415	0.755168625681439	CTNNB1	1
GO:0070988	demethylation	1/319	73/18722	0.715490585509415	0.755168625681439	KDM6B	1
GO:0086003	cardiac muscle cell contraction	1/319	73/18722	0.715490585509415	0.755168625681439	PDE4B	1
GO:0016331	morphogenesis of embryonic epithelium	2/319	147/18722	0.717514698429317	0.757110607095206	HIF1A/CTNNB1	2
GO:0048562	embryonic organ morphogenesis	4/319	285/18722	0.718657460650483	0.75812184263129	HIF1A/CTNNB1/ID2/HES1	4
GO:0006635	fatty acid beta-oxidation	1/319	74/18722	0.720357254136285	0.758746777287796	IRS2	1
GO:0009201	ribonucleoside triphosphate biosynthetic process	1/319	74/18722	0.720357254136285	0.758746777287796	TMSB4X	1
GO:0033143	regulation of intracellular steroid hormone receptor signaling pathway	1/319	74/18722	0.720357254136285	0.758746777287796	DDX5	1
GO:0046470	phosphatidylcholine metabolic process	1/319	74/18722	0.720357254136285	0.758746777287796	APOC1	1
GO:0070972	protein localization to endoplasmic reticulum	1/319	74/18722	0.720357254136285	0.758746777287796	PPP1R15A	1
GO:0120192	tight junction assembly	1/319	74/18722	0.720357254136285	0.758746777287796	TNF	1
GO:0042445	hormone metabolic process	3/319	218/18722	0.721159644969625	0.75939736180075	HIF1A/EGR1/SPP1	3
GO:1905039	carboxylic acid transmembrane transport	2/319	149/18722	0.724440305284998	0.762656618444719	IRS2/THBS1	2
GO:0006024	glycosaminoglycan biosynthetic process	1/319	75/18722	0.725140932596737	0.7630034230625	IL1B	1
GO:0036465	synaptic vesicle recycling	1/319	75/18722	0.725140932596737	0.7630034230625	SNCA	1
GO:0048705	skeletal system morphogenesis	3/319	220/18722	0.726874835770608	0.764632151958283	CSRNP1/CTNNB1/TMEM107	3
GO:1903825	organic acid transmembrane transport	2/319	150/18722	0.727849126522756	0.76546118166668	IRS2/THBS1	2
GO:0006305	DNA alkylation	1/319	76/18722	0.729843031728053	0.766381788872037	FOS	1
GO:0006306	DNA methylation	1/319	76/18722	0.729843031728053	0.766381788872037	FOS	1
GO:0009123	nucleoside monophosphate metabolic process	1/319	76/18722	0.729843031728053	0.766381788872037	TYMP	1
GO:0014855	striated muscle cell proliferation	1/319	76/18722	0.729843031728053	0.766381788872037	PIM1	1
GO:0032720	negative regulation of tumor necrosis factor production	1/319	76/18722	0.729843031728053	0.766381788872037	TNFAIP3	1
GO:0140115	export across plasma membrane	1/319	76/18722	0.729843031728053	0.766381788872037	ATP1B3	1
GO:0055067	monovalent inorganic cation homeostasis	2/319	151/18722	0.731222251091564	0.767633982185245	ATP1B3/IL1A	2
GO:0048644	muscle organ morphogenesis	1/319	77/18722	0.734464938457579	0.77064455385378	SERP1	1
GO:0055117	regulation of cardiac muscle contraction	1/319	77/18722	0.734464938457579	0.77064455385378	PDE4B	1
GO:0120254	olefinic compound metabolic process	2/319	153/18722	0.737862302394174	0.774011718586999	PTGS2/EGR1	2
GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	1/319	78/18722	0.739008016206683	0.774225778446909	RGS1	1
GO:0034637	cellular carbohydrate biosynthetic process	1/319	78/18722	0.739008016206683	0.774225778446909	IRS2	1
GO:0043297	apical junction assembly	1/319	78/18722	0.739008016206683	0.774225778446909	TNF	1
GO:1901616	organic hydroxy compound catabolic process	1/319	78/18722	0.739008016206683	0.774225778446909	APOE	1
GO:1903556	negative regulation of tumor necrosis factor superfamily cytokine production	1/319	78/18722	0.739008016206683	0.774225778446909	TNFAIP3	1
GO:0006023	aminoglycan biosynthetic process	1/319	79/18722	0.743473605287892	0.778309139632932	IL1B	1
GO:0006029	proteoglycan metabolic process	1/319	79/18722	0.743473605287892	0.778309139632932	CTNNB1	1
GO:0051279	regulation of release of sequestered calcium ion into cytosol	1/319	79/18722	0.743473605287892	0.778309139632932	SNCA	1
GO:0010970	transport along microtubule	2/319	155/18722	0.744362270602594	0.779041062741157	HIF1A/HNRNPU	2
GO:0032259	methylation	5/319	364/18722	0.74613845020389	0.780701239192719	FOS/ETF1/CTNNB1/BTG1/PRMT9	5
GO:0021766	hippocampus development	1/319	80/18722	0.747863023295357	0.782107577910764	KDM6B	1
GO:0120193	tight junction organization	1/319	80/18722	0.747863023295357	0.782107577910764	TNF	1
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	1/319	81/18722	0.752177565488725	0.786419626582948	SKIL	1
GO:0009205	purine ribonucleoside triphosphate metabolic process	1/319	82/18722	0.756418505170561	0.790250692441214	TMSB4X	1
GO:0043242	negative regulation of protein-containing complex disassembly	1/319	82/18722	0.756418505170561	0.790250692441214	TNF	1
GO:0072527	pyrimidine-containing compound metabolic process	1/319	82/18722	0.756418505170561	0.790250692441214	TYMP	1
GO:0046488	phosphatidylinositol metabolic process	2/319	159/18722	0.756949397841004	0.790604414259239	SOCS3/PLEK	2
GO:0030198	extracellular matrix organization	4/319	301/18722	0.757295803588738	0.79076531586317	DNAJB6/TNF/RGCC/FBLN1	4
GO:0043062	extracellular structure organization	4/319	302/18722	0.759568983375746	0.792736250484308	DNAJB6/TNF/RGCC/FBLN1	4
GO:0051056	regulation of small GTPase mediated signal transduction	4/319	302/18722	0.759568983375746	0.792736250484308	TAGAP/GABARAP/BCL6/APOE	4
GO:0003205	cardiac chamber development	2/319	161/18722	0.763040360215451	0.795955067456412	HIF1A/HES1	2
GO:0051650	establishment of vesicle localization	2/319	161/18722	0.763040360215451	0.795955067456412	CTNNB1/SNCA	2
GO:0045229	external encapsulating structure organization	4/319	304/18722	0.764066018350531	0.796457622759484	DNAJB6/TNF/RGCC/FBLN1	4
GO:0006835	dicarboxylic acid transport	1/319	84/18722	0.764684562644535	0.796457622759484	SNCA	1
GO:0009953	dorsal/ventral pattern formation	1/319	84/18722	0.764684562644535	0.796457622759484	CTNNB1	1
GO:0015844	monoamine transport	1/319	84/18722	0.764684562644535	0.796457622759484	SNCA	1
GO:0032508	DNA duplex unwinding	1/319	84/18722	0.764684562644535	0.796457622759484	CHD1	1
GO:0042440	pigment metabolic process	1/319	84/18722	0.764684562644535	0.796457622759484	HMOX1	1
GO:0006310	DNA recombination	4/319	305/18722	0.766289960475954	0.797927565227114	BCL6/HMGB2/HMGB1/STAT6	4
GO:0006650	glycerophospholipid metabolic process	4/319	306/18722	0.768497579104311	0.799639556589464	SOCS3/PLEK/DGKZ/APOC1	4
GO:0009142	nucleoside triphosphate biosynthetic process	1/319	85/18722	0.768712120564719	0.799639556589464	TMSB4X	1
GO:0072384	organelle transport along microtubule	1/319	85/18722	0.768712120564719	0.799639556589464	HIF1A	1
GO:2000779	regulation of double-strand break repair	1/319	85/18722	0.768712120564719	0.799639556589464	DEK	1
GO:0010976	positive regulation of neuron projection development	2/319	163/18722	0.768998837514924	0.799735446755338	SNX3/APOE	2
GO:0045921	positive regulation of exocytosis	1/319	86/18722	0.772670956940737	0.803147990893393	SNCA	1
GO:0046928	regulation of neurotransmitter secretion	1/319	86/18722	0.772670956940737	0.803147990893393	SNCA	1
GO:0007286	spermatid development	2/319	165/18722	0.774826795639705	0.805185277268662	HMGB2/DEFB1	2
GO:1901879	regulation of protein depolymerization	1/319	87/18722	0.776562240732104	0.806784779289785	PLEK	1
GO:0009144	purine nucleoside triphosphate metabolic process	1/319	88/18722	0.78038712107589	0.810084142214915	TMSB4X	1
GO:0030101	natural killer cell activation	1/319	88/18722	0.78038712107589	0.810084142214915	NFIL3	1
GO:1901657	glycosyl compound metabolic process	1/319	88/18722	0.78038712107589	0.810084142214915	TYMP	1
GO:0055088	lipid homeostasis	2/319	167/18722	0.78052621924429	0.810084142214915	IRS2/APOE	2
GO:0060047	heart contraction	3/319	241/18722	0.781460598301766	0.810849197278788	CXCR4/PDE4B/HBEGF	3
GO:0009199	ribonucleoside triphosphate metabolic process	1/319	89/18722	0.784146727621817	0.813431036400022	TMSB4X	1
GO:0006644	phospholipid metabolic process	5/319	383/18722	0.784481232388429	0.813572741258535	SOCS3/SNCA/PLEK/DGKZ/APOC1	5
GO:0009152	purine ribonucleotide biosynthetic process	2/319	169/18722	0.786099108240143	0.814901917684787	TMSB4X/SNCA	2
GO:0043543	protein acylation	3/319	243/18722	0.786159329977588	0.814901917684787	IL1B/SNCA/SET	3
GO:0006400	tRNA modification	1/319	90/18722	0.787842170861694	0.815618021760873	SSB	1
GO:0035278	miRNA mediated inhibition of translation	1/319	90/18722	0.787842170861694	0.815618021760873	ZFP36	1
GO:0040033	negative regulation of translation, ncRNA-mediated	1/319	90/18722	0.787842170861694	0.815618021760873	ZFP36	1
GO:0042475	odontogenesis of dentin-containing tooth	1/319	90/18722	0.787842170861694	0.815618021760873	CTNNB1	1
GO:0097581	lamellipodium organization	1/319	90/18722	0.787842170861694	0.815618021760873	BRK1	1
GO:0006814	sodium ion transport	3/319	245/18722	0.790774391254522	0.81834804930221	SGK1/YWHAH/ATP1B3	3
GO:0042147	retrograde transport, endosome to Golgi	1/319	91/18722	0.791474542453317	0.81834804930221	SNX3	1
GO:0045974	regulation of translation, ncRNA-mediated	1/319	91/18722	0.791474542453317	0.81834804930221	ZFP36	1
GO:0051952	regulation of amine transport	1/319	91/18722	0.791474542453317	0.81834804930221	SNCA	1
GO:0098661	inorganic anion transmembrane transport	1/319	91/18722	0.791474542453317	0.81834804930221	PRNP	1
GO:0009101	glycoprotein biosynthetic process	4/319	317/18722	0.791718185234473	0.81839413112872	HBEGF/CTNNB1/SERP1/DAD1	4
GO:0009100	glycoprotein metabolic process	5/319	387/18722	0.791956715531527	0.818434906372577	HIF1A/HBEGF/CTNNB1/SERP1/DAD1	5
GO:0048515	spermatid differentiation	2/319	172/18722	0.794225592852227	0.819955151234432	HMGB2/DEFB1	2
GO:0048736	appendage development	2/319	172/18722	0.794225592852227	0.819955151234432	CTNNB1/TMEM107	2
GO:0060173	limb development	2/319	172/18722	0.794225592852227	0.819955151234432	CTNNB1/TMEM107	2
GO:1901136	carbohydrate derivative catabolic process	2/319	172/18722	0.794225592852227	0.819955151234432	PDE4B/TYMP	2
GO:0001708	cell fate specification	1/319	92/18722	0.795044915538895	0.820594940441977	CTNNB1	1
GO:0060349	bone morphogenesis	1/319	93/18722	0.798554345058116	0.823803491225575	TMEM107	1
GO:1901992	positive regulation of mitotic cell cycle phase transition	1/319	93/18722	0.798554345058116	0.823803491225575	RGCC	1
GO:0014020	primary neural tube formation	1/319	94/18722	0.80200386805594	0.826609589071002	HIF1A	1
GO:0048704	embryonic skeletal system morphogenesis	1/319	94/18722	0.80200386805594	0.826609589071002	CTNNB1	1
GO:0003341	cilium movement	2/319	175/18722	0.802078727999082	0.826609589071002	DNAJA1/DEFB1	2
GO:0050954	sensory perception of mechanical stimulus	2/319	175/18722	0.802078727999082	0.826609589071002	CXCR4/ICAM1	2
GO:0003015	heart process	3/319	251/18722	0.804126224804773	0.828304412471165	CXCR4/PDE4B/HBEGF	3
GO:0006302	double-strand break repair	3/319	251/18722	0.804126224804773	0.828304412471165	HMGB2/DEK/HMGB1	3
GO:0045666	positive regulation of neuron differentiation	1/319	95/18722	0.805394503985194	0.829403007485755	BCL6	1
GO:0045017	glycerolipid biosynthetic process	3/319	252/18722	0.806280751015648	0.829899891693873	SOCS3/C3/DGKZ	3
GO:0061448	connective tissue development	3/319	252/18722	0.806280751015648	0.829899891693873	HIF1A/CTNNB1/EGR1	3
GO:0051648	vesicle localization	2/319	177/18722	0.807165672082361	0.830339097233207	CTNNB1/SNCA	2
GO:0060828	regulation of canonical Wnt signaling pathway	3/319	253/18722	0.80841535713275	0.830339097233207	TLE3/EGR1/APOE	3
GO:0003073	regulation of systemic arterial blood pressure	1/319	96/18722	0.808727255004077	0.830339097233207	SOD2	1
GO:0006637	acyl-CoA metabolic process	1/319	96/18722	0.808727255004077	0.830339097233207	SNCA	1
GO:0035282	segmentation	1/319	96/18722	0.808727255004077	0.830339097233207	BASP1	1
GO:0035383	thioester metabolic process	1/319	96/18722	0.808727255004077	0.830339097233207	SNCA	1
GO:0042158	lipoprotein biosynthetic process	1/319	96/18722	0.808727255004077	0.830339097233207	APOE	1
GO:0042632	cholesterol homeostasis	1/319	96/18722	0.808727255004077	0.830339097233207	APOE	1
GO:0051304	chromosome separation	1/319	96/18722	0.808727255004077	0.830339097233207	DUSP1	1
GO:0055017	cardiac muscle tissue growth	1/319	96/18722	0.808727255004077	0.830339097233207	PIM1	1
GO:0035725	sodium ion transmembrane transport	2/319	178/18722	0.809665361898312	0.831094707306857	YWHAH/ATP1B3	2
GO:0035335	peptidyl-tyrosine dephosphorylation	1/319	97/18722	0.812003106268637	0.832591502792571	DUSP1	1
GO:0055092	sterol homeostasis	1/319	97/18722	0.812003106268637	0.832591502792571	APOE	1
GO:0070252	actin-mediated cell contraction	1/319	97/18722	0.812003106268637	0.832591502792571	PDE4B	1
GO:0006399	tRNA metabolic process	2/319	179/18722	0.812136201945563	0.832591502792571	LSM6/SSB	2
GO:0007416	synapse assembly	2/319	179/18722	0.812136201945563	0.832591502792571	SNCA/SEMA4D	2
GO:0015837	amine transport	1/319	99/18722	0.818387966868727	0.838373519012543	SNCA	1
GO:0051153	regulation of striated muscle cell differentiation	1/319	99/18722	0.818387966868727	0.838373519012543	YBX1	1
GO:0060996	dendritic spine development	1/319	99/18722	0.818387966868727	0.838373519012543	APOE	1
GO:0009260	ribonucleotide biosynthetic process	2/319	182/18722	0.819378158123763	0.83896976539148	TMSB4X/SNCA	2
GO:0051260	protein homooligomerization	2/319	182/18722	0.819378158123763	0.83896976539148	SOD2/PRNP	2
GO:0006910	phagocytosis, recognition	1/319	100/18722	0.821498864069439	0.840304013483321	FCN1	1
GO:0009062	fatty acid catabolic process	1/319	100/18722	0.821498864069439	0.840304013483321	IRS2	1
GO:0044728	DNA methylation or demethylation	1/319	100/18722	0.821498864069439	0.840304013483321	FOS	1
GO:0051588	regulation of neurotransmitter transport	1/319	100/18722	0.821498864069439	0.840304013483321	SNCA	1
GO:0001841	neural tube formation	1/319	102/18722	0.827562192415433	0.845874732227709	HIF1A	1
GO:1904063	negative regulation of cation transmembrane transport	1/319	102/18722	0.827562192415433	0.845874732227709	PPIF	1
GO:1990542	mitochondrial transmembrane transport	1/319	102/18722	0.827562192415433	0.845874732227709	SLC25A37	1
GO:0120032	regulation of plasma membrane bounded cell projection assembly	2/319	186/18722	0.828645552291235	0.846771530069418	ICAM1/BRK1	2
GO:0003279	cardiac septum development	1/319	103/18722	0.830516416938499	0.84847241303036	HES1	1
GO:0048839	inner ear development	2/319	188/18722	0.833117257434452	0.850706667986347	ANP32B/HES1	2
GO:0060491	regulation of cell projection assembly	2/319	188/18722	0.833117257434452	0.850706667986347	ICAM1/BRK1	2
GO:0006892	post-Golgi vesicle-mediated transport	1/319	104/18722	0.833420185293223	0.850804663953425	VAMP5	1
GO:0120034	positive regulation of plasma membrane bounded cell projection assembly	1/319	105/18722	0.836274356573246	0.853506424993201	BRK1	1
GO:0009566	fertilization	2/319	190/18722	0.83748363398346	0.853892663518354	VDAC2/YBX3	2
GO:0046390	ribose phosphate biosynthetic process	2/319	190/18722	0.83748363398346	0.853892663518354	TMSB4X/SNCA	2
GO:0051216	cartilage development	2/319	190/18722	0.83748363398346	0.853892663518354	HIF1A/CTNNB1	2
GO:0099111	microtubule-based transport	2/319	190/18722	0.83748363398346	0.853892663518354	HIF1A/HNRNPU	2
GO:0002062	chondrocyte differentiation	1/319	106/18722	0.839079775290179	0.855095923703006	CTNNB1	1
GO:0007218	neuropeptide signaling pathway	1/319	106/18722	0.839079775290179	0.855095923703006	GPR84	1
GO:0006164	purine nucleotide biosynthetic process	2/319	191/18722	0.839627944844453	0.855442498452428	TMSB4X/SNCA	2
GO:0021761	limbic system development	1/319	107/18722	0.841837271620348	0.857480927559775	KDM6B	1
GO:0006958	complement activation, classical pathway	1/319	108/18722	0.844547661647375	0.860028594756591	C3	1
GO:0006821	chloride transport	1/319	109/18722	0.847211747600662	0.862314309083021	PRNP	1
GO:0034766	negative regulation of ion transmembrane transport	1/319	109/18722	0.847211747600662	0.862314309083021	PPIF	1
GO:0003014	renal system process	1/319	110/18722	0.849830318089857	0.864551456982777	SGK1	1
GO:0006939	smooth muscle contraction	1/319	110/18722	0.849830318089857	0.864551456982777	PTGS2	1
GO:0015718	monocarboxylic acid transport	1/319	111/18722	0.852404148335362	0.86695533246083	IL1B	1
GO:0001676	long-chain fatty acid metabolic process	1/319	112/18722	0.854934000394952	0.869098337196747	PTGS2	1
GO:0009141	nucleoside triphosphate metabolic process	1/319	112/18722	0.854934000394952	0.869098337196747	TMSB4X	1
GO:0001578	microtubule bundle formation	1/319	113/18722	0.85742062338657	0.871410675585213	MAPRE1	1
GO:0072522	purine-containing compound biosynthetic process	2/319	200/18722	0.857804563499072	0.871585407944806	TMSB4X/SNCA	2
GO:0051261	protein depolymerization	1/319	114/18722	0.859864753707365	0.873462812574989	PLEK	1
GO:0034968	histone lysine methylation	1/319	115/18722	0.862267115249033	0.875686786262049	CTNNB1	1
GO:0008016	regulation of heart contraction	2/319	206/18722	0.868857870710679	0.882162189797877	PDE4B/HBEGF	2
GO:0006304	DNA modification	1/319	120/18722	0.873676878474962	0.886835962323598	FOS	1
GO:0048706	embryonic skeletal system development	1/319	121/18722	0.875843154991815	0.888815406114873	CTNNB1	1
GO:0046474	glycerophospholipid biosynthetic process	2/319	211/18722	0.877461439126687	0.890237901344968	SOCS3/DGKZ	2
GO:0072329	monocarboxylic acid catabolic process	1/319	122/18722	0.877972397159312	0.89053652226053	IRS2	1
GO:0043583	ear development	2/319	213/18722	0.88075511662879	0.893138698683018	ANP32B/HES1	2
GO:0044242	cellular lipid catabolic process	2/319	214/18722	0.882371183845616	0.894556827814877	IRS2/APOC1	2
GO:0030048	actin filament-based movement	1/319	127/18722	0.888084812404982	0.899905512397555	PDE4B	1
GO:0035270	endocrine system development	1/319	127/18722	0.888084812404982	0.899905512397555	HES1	1
GO:0033865	nucleoside bisphosphate metabolic process	1/319	128/18722	0.890004734149689	0.901112275115398	SNCA	1
GO:0033875	ribonucleoside bisphosphate metabolic process	1/319	128/18722	0.890004734149689	0.901112275115398	SNCA	1
GO:0034032	purine nucleoside bisphosphate metabolic process	1/319	128/18722	0.890004734149689	0.901112275115398	SNCA	1
GO:0071805	potassium ion transmembrane transport	2/319	219/18722	0.890152505289134	0.901112275115398	ATP1B3/PRNP	2
GO:0007018	microtubule-based movement	4/319	382/18722	0.893252494237682	0.904027819746704	HIF1A/DNAJA1/HNRNPU/DEFB1	4
GO:0042476	odontogenesis	1/319	130/18722	0.893746632276594	0.904305292958178	CTNNB1	1
GO:0006661	phosphatidylinositol biosynthetic process	1/319	131/18722	0.895569718781745	0.905704087063162	SOCS3	1
GO:0018022	peptidyl-lysine methylation	1/319	131/18722	0.895569718781745	0.905704087063162	CTNNB1	1
GO:0006486	protein glycosylation	2/319	226/18722	0.900247666236424	0.90998725249519	SERP1/DAD1	2
GO:0043413	macromolecule glycosylation	2/319	226/18722	0.900247666236424	0.90998725249519	SERP1/DAD1	2
GO:0001508	action potential	1/319	134/18722	0.900853992353381	0.910376293649152	YWHAH	1
GO:0007411	axon guidance	2/319	227/18722	0.901617344065855	0.910923789986416	VEGFA/SEMA4D	2
GO:0097485	neuron projection guidance	2/319	228/18722	0.902969502581174	0.912065755555579	VEGFA/SEMA4D	2
GO:0046394	carboxylic acid biosynthetic process	3/319	314/18722	0.905749658698471	0.914547751694769	IL1B/PTGS2/APOC1	3
GO:0008203	cholesterol metabolic process	1/319	137/18722	0.905871672318438	0.914547751694769	APOE	1
GO:0007224	smoothened signaling pathway	1/319	138/18722	0.90748732669188	0.915953940591779	HES1	1
GO:0016053	organic acid biosynthetic process	3/319	316/18722	0.908008640361291	0.916255159677287	IL1B/PTGS2/APOC1	3
GO:0030177	positive regulation of Wnt signaling pathway	1/319	140/18722	0.910636168266125	0.918681052206635	TNFAIP3	1
GO:0016571	histone methylation	1/319	141/18722	0.912170290660006	0.920002959986086	CTNNB1	1
GO:0006865	amino acid transport	1/319	143/18722	0.915160217307444	0.922792164177313	SNCA	1
GO:0070085	glycosylation	2/319	240/18722	0.917898973877489	0.925326797844619	SERP1/DAD1	2
GO:0006813	potassium ion transport	2/319	241/18722	0.919040717606156	0.9262506472368	ATP1B3/PRNP	2
GO:0060041	retina development in camera-type eye	1/319	147/18722	0.92083907673406	0.927608293176604	HIF1A	1
GO:1902652	secondary alcohol metabolic process	1/319	147/18722	0.92083907673406	0.927608293176604	APOE	1
GO:0044272	sulfur compound biosynthetic process	1/319	148/18722	0.922198556385303	0.928522719887333	SNCA	1
GO:0050905	neuromuscular process	1/319	148/18722	0.922198556385303	0.928522719887333	NR4A1	1
GO:0098656	anion transmembrane transport	2/319	245/18722	0.923460345434125	0.929565494632636	VDAC2/PRNP	2
GO:0006261	DNA-dependent DNA replication	1/319	151/18722	0.926138926096388	0.932033567976072	BCL6	1
GO:0016125	sterol metabolic process	1/319	152/18722	0.927407661359716	0.93308196178409	APOE	1
GO:0007338	single fertilization	1/319	153/18722	0.928654670300278	0.934107988648017	VDAC2	1
GO:0060271	cilium assembly	3/319	337/18722	0.92893356849885	0.934159955992851	MAPRE1/RILPL2/TMEM107	3
GO:0007605	sensory perception of sound	1/319	154/18722	0.929880323818196	0.934883348304379	ICAM1	1
GO:0008654	phospholipid biosynthetic process	2/319	253/18722	0.931627552206964	0.936410969956681	SOCS3/DGKZ	2
GO:0009165	nucleotide biosynthetic process	2/319	254/18722	0.932588642633473	0.937147863570327	TMSB4X/SNCA	2
GO:0007030	Golgi organization	1/319	157/18722	0.933432766795395	0.937766887657837	VMP1	1
GO:1901293	nucleoside phosphate biosynthetic process	2/319	256/18722	0.934472687461002	0.93858226683415	TMSB4X/SNCA	2
GO:0035637	multicellular organismal signaling	1/319	160/18722	0.936805769465234	0.940695778766873	TYMP	1
GO:0051321	meiotic cell cycle	2/319	261/18722	0.938967424824651	0.942636162015663	DUSP1/EREG	2
GO:0006066	alcohol metabolic process	3/319	353/18722	0.941845378267805	0.94529451905736	SNCA/PLEK/APOE	3
GO:0015711	organic anion transport	3/319	354/18722	0.942575665617088	0.945796573432231	IL1B/SNCA/SLC2A3	3
GO:0009451	RNA modification	1/319	167/18722	0.944028201095764	0.947022922085087	SSB	1
GO:0016482	cytosolic transport	1/319	168/18722	0.94499047562287	0.94775697616141	SNX3	1
GO:0046942	carboxylic acid transport	2/319	273/18722	0.948592731293934	0.951137736182772	IL1B/SNCA	2
GO:0044782	cilium organization	3/319	368/18722	0.951947144185451	0.954268400328307	MAPRE1/RILPL2/TMEM107	3
GO:0140013	meiotic nuclear division	1/319	185/18722	0.959041708825338	0.961145895899796	EREG	1
GO:0048193	Golgi vesicle transport	2/319	296/18722	0.963150525018873	0.96502846901111	SNX3/VAMP5	2
GO:1903046	meiotic cell cycle process	1/319	202/18722	0.969512120720423	0.971165771998455	EREG	1
GO:0007601	visual perception	1/319	215/18722	0.97567792524724	0.97710400747659	TIMP3	1
GO:0050953	sensory perception of light stimulus	1/319	219/18722	0.977312124442711	0.978502226883581	TIMP3	1
GO:0046395	carboxylic acid catabolic process	1/319	236/18722	0.983121204371774	0.984078712240653	IRS2	1
GO:0016054	organic acid catabolic process	1/319	240/18722	0.98425654492537	0.984975330133445	IRS2	1
GO:0044282	small molecule catabolic process	2/319	376/18722	0.988811085085479	0.989292375465174	IRS2/APOE	2
GO:0090305	nucleic acid phosphodiester bond hydrolysis	1/319	261/18722	0.989079958862682	0.989320610920799	ZFP36	1
GO:0006790	sulfur compound metabolic process	1/319	339/18722	0.99720414975884	0.99720414975884	SNCA	1