ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	geneID	Count
GO:0003735	structural constituent of ribosome	60/571	182/18367	4.2558935161293e-45	3.17064066951633e-42	RPL23A/RPS10/RPS3A/RPL17/RPS6/RPL15/RPL7/RPL36A/RPS8/RPS16/RPL6/RPS3/RPL7A/RPL26/RPL14/RPL5/RPL23/RPS4X/RPS17/RPL27A/RPL3/RPS2/RPL9/RPL13A/RPS11/RPS20/RPL31/RPLP0/RPS18/RPSA/RPS13/RPL10A/RPL24/RPL11/RPL41/RPL21/RPL13/MRPS15/RPL27/RPS27A/RPS19/RPL19/RPL10/RPL8/RPS25/RPS5/RPS15A/RPL18A/MRPL51/RPL38/MRPS35/MRPS6/RPL29/MRPS7/RPL4/RPS9/MRPL13/MRPL19/MRPL21/RPL7L1	60
GO:0019843	rRNA binding	19/571	68/18367	1.38191786766911e-13	5.14764405706745e-11	RPL23A/NPM1/RPS3/RPL5/RPL23/RPS4X/RPL9/RPS11/RPLP0/RPS18/RPS13/RPL11/RPL19/RPL8/RPS5/MRPS6/CIRBP/MRPS7/RPS9	19
GO:0045296	cadherin binding	40/571	332/18367	2.14436297986296e-13	5.32516806665967e-11	RPL23A/LDHA/RPL15/RANBP1/RPL6/PFN1/RPL7A/RPL14/RPS2/RAN/ALDOA/EIF3E/HSP90AB1/ENO1/ANXA1/PRDX1/RPL24/PKM/CDH1/CCT8/ZC3H15/EGFR/PPP1CA/NUDC/PARK7/ITGA6/SNX2/AHNAK/CHMP5/S100P/RPL29/ITGB1/CCNB2/CD46/RSL1D1/KRT18/IQGAP1/MACF1/RUVBL1/EIF2A	40
GO:0051082	unfolded protein binding	23/571	122/18367	3.19233793249744e-12	5.94572939927649e-10	NPM1/HSP90AB1/DNAJA1/PPIA/TUBB4B/CCT8/CCT5/CCT6A/NACA/PTGES3/NUDC/CCT7/CCT3/HSPA9/TCP1/CCT2/HSPD1/HSPE1/LMAN1/HSP90B1/PFDN4/CANX/CALR	23
GO:0044183	protein folding chaperone	11/571	40/18367	2.42834580243033e-08	3.6182352456212e-06	CD74/HSP90AB1/CCT8/CCT5/CCT6A/CCT7/CCT3/HSPA9/TCP1/CCT2/CALR	11
GO:0005178	integrin binding	18/571	144/18367	5.42783891831775e-07	6.57108744104203e-05	FN1/FBN1/SPP1/LAMA5/HMGB1/PPIA/EGFR/LAMB1/ITGB8/ITGAV/ITGB1/ITGB4/GPNMB/IGF2/PLPP3/FBLN1/P4HB/CALR	18
GO:0031625	ubiquitin protein ligase binding	27/571	297/18367	6.75542830092622e-07	6.57108744104203e-05	RPL5/RPL23/TPI1/ACTG1/HSP90AB1/PA2G4/SLC25A5/DNAJA1/UBE2L3/RPL11/TUBA1B/UBE2N/UBE2T/PSMA3/EGFR/CACYBP/RPS27A/SUMO2/HSPA9/TCP1/CCT2/HSPD1/BAG2/GABARAP/UBXN1/TXNIP/CALR	27
GO:0044389	ubiquitin-like protein ligase binding	28/571	316/18367	7.05620127897131e-07	6.57108744104203e-05	RPL5/RPL23/TPI1/ACTG1/HSP90AB1/PA2G4/SLC25A5/DNAJA1/UBE2L3/RPL11/TUBA1B/UBE2N/UBE2T/PSMA3/CCNB1/EGFR/CACYBP/RPS27A/SUMO2/HSPA9/TCP1/CCT2/HSPD1/BAG2/GABARAP/UBXN1/TXNIP/CALR	28
GO:0043021	ribonucleoprotein complex binding	18/571	149/18367	9.03196609727522e-07	6.82421796654607e-05	NEAT1/NPM1/SNRPD1/YBX3/RPSA/SRP9/NME1/PPP1CA/SNRPD2/EIF4A3/SNRPB/EIF1/PPIH/SNRPG/SRP19/MALSU1/EIF2A/SEC61A1	18
GO:0023026	MHC class II protein complex binding	8/571	27/18367	1.09400301793075e-06	6.82421796654607e-05	CD74/HLA-DRB1/HSP90AB1/HLA-DPA1/HLA-DRA/HLA-DPB1/PKM/B2M	8
GO:0048027	mRNA 5'-UTR binding	8/571	27/18367	1.09400301793075e-06	6.82421796654607e-05	RPS3A/RPL26/RPL5/RPS13/RPL41/NCL/CCT5/RSL1D1	8
GO:0051087	chaperone binding	15/571	107/18367	1.09920289394031e-06	6.82421796654607e-05	FN1/LRP2/HLA-B/DNAJA1/DNAJC9/PTGES3/BIRC5/HSPD1/AMFR/BAG2/GRN/HSPE1/PFDN4/TIMM9/CALR	15
GO:0045182	translation regulator activity	16/571	140/18367	7.48357535289393e-06	0.000405014206030556	EEF1B2/EEF1A1/EIF3E/TYMS/EIF3H/EIF4A3/RPL10/EIF1/EIF1AX/CIRBP/EIF2S2/EIF3I/RPS9/ABCF1/EIF2A/COPS5	16
GO:0050840	extracellular matrix binding	10/571	56/18367	7.65422082264045e-06	0.000405014206030556	SPP1/LGALS1/RPSA/SPARC/BCAM/ADGRG1/ITGA6/ITGAV/ITGB1/DAG1	10
GO:0019838	growth factor binding	16/571	141/18367	8.20338499020547e-06	0.000405014206030556	LRP2/RPS2/CRIM1/FLT1/IL6ST/COL4A1/EGFR/RPS19/ITGA6/ITGAV/NRP1/ENG/ITGB4/GLG1/IGF1R/HTRA1	16
GO:0033218	amide binding	30/571	400/18367	8.69829167313945e-06	0.000405014206030556	CD74/APOE/HLA-B/HLA-C/HLA-DRB1/HSP90AB1/VDAC2/HLA-DPA1/HLA-A/VDAC1/HLA-DRA/HLA-DPB1/PPIA/ITM2B/LRP1/ACBD6/TYMS/PSAP/SLC19A1/PPIH/MTHFS/CLSTN1/PFDN4/PRLR/SLC40A1/MME/FOLR1/IGF1R/SEC61A1/CALR	30
GO:0004857	enzyme inhibitor activity	11/571	70/18367	9.76810517532442e-06	0.000428072844448041	RPL5/RPL23/APOC1/RPS20/DYNLL1/ANXA1/RPL11/ANXA5/OAZ1/ANXA3/TXNIP	11
GO:0023023	MHC protein complex binding	8/571	36/18367	1.16495102742745e-05	0.000482160286351915	CD74/HLA-DRB1/HSP90AB1/HLA-DPA1/HLA-DRA/HLA-DPB1/PKM/B2M	8
GO:0017154	semaphorin receptor activity	5/571	12/18367	1.88532360148433e-05	0.000739245306897805	PLXNA1/PLXNB1/MET/NRP1/PLXNB2	5
GO:0001618	virus receptor activity	11/571	76/18367	2.18491102242814e-05	0.00081387935585448	RPSA/EGFR/CDK1/ITGAV/ITGB1/SLC52A1/DAG1/CD46/DPP4/TFRC/SLC1A5	11
GO:0005520	insulin-like growth factor binding	7/571	29/18367	2.32692507869844e-05	0.000825504373157305	LRP2/CRIM1/ITGA6/ITGAV/ITGB4/IGF1R/HTRA1	7
GO:0140272	exogenous protein binding	11/571	77/18367	2.47860879583607e-05	0.000839347069499034	RPSA/EGFR/CDK1/ITGAV/ITGB1/SLC52A1/DAG1/CD46/DPP4/TFRC/SLC1A5	11
GO:0031994	insulin-like growth factor I binding	5/571	13/18367	2.98535076718494e-05	0.000966994052849035	LRP2/ITGA6/ITGAV/ITGB4/IGF1R	5
GO:0055106	ubiquitin-protein transferase regulator activity	6/571	22/18367	4.28866746819719e-05	0.00133127385991954	RPL5/RPL23/RPS20/UBE2L3/RPL11/CDC20	6
GO:0008135	translation factor activity, RNA binding	11/571	84/18367	5.66367540945905e-05	0.0016877752720188	EEF1B2/EEF1A1/EIF3E/EIF3H/EIF1/EIF1AX/EIF2S2/EIF3I/ABCF1/EIF2A/COPS5	11
GO:0016209	antioxidant activity	11/571	86/18367	7.0538061823702e-05	0.00202118677148685	APOE/PRDX1/GSTP1/PRDX3/GPX1/PARK7/HBA2/TXN/GSTO1/GLRX/HBB	11
GO:0042605	peptide antigen binding	7/571	36/18367	0.000103050632230248	0.00284343411153831	HLA-B/HLA-C/HLA-DRB1/HLA-DPA1/HLA-A/HLA-DRA/HLA-DPB1	7
GO:0003697	single-stranded DNA binding	13/571	123/18367	0.000119163049998886	0.00317058829461321	YBX1/HNRNPA1/HMGB2/HMGB1/ANXA1/SUB1/NME1/RPA3/HSPD1/HNRNPA2B1/RAD51/POLR2H/SMARCA1	13
GO:0090079	translation regulator activity, nucleic acid binding	12/571	108/18367	0.000133971407135644	0.00344167925227774	EEF1B2/EEF1A1/EIF3E/TYMS/EIF3H/EIF1/EIF1AX/EIF2S2/EIF3I/ABCF1/EIF2A/COPS5	12
GO:0003743	translation initiation factor activity	8/571	51/18367	0.000162738164725696	0.00404133109068811	EIF3E/EIF3H/EIF1/EIF1AX/EIF2S2/EIF3I/EIF2A/COPS5	8
GO:0140678	molecular function inhibitor activity	13/571	128/18367	0.000178400197023534	0.0042873595736301	RPL5/RPL23/APOC1/RPS20/DYNLL1/CALM1/ANXA1/RPL11/PHPT1/ANXA5/OAZ1/ANXA3/TXNIP	13
GO:0043236	laminin binding	6/571	28/18367	0.000184759955187972	0.00430144270671997	LGALS1/RPSA/BCAM/ITGA6/ITGB1/DAG1	6
GO:0008201	heparin binding	15/571	166/18367	0.000216597787147529	0.00488985913408815	FN1/FBN1/APOE/AOC1/PRG2/FSTL1/SERPINE2/PTPRF/ADGRG1/RPL29/NRP1/PDCD5/APLP2/APP/GPNMB	15
GO:0097493	structural molecule activity conferring elasticity	4/571	11/18367	0.00025625474837739	0.00561499375121046	FBN2/FBN1/LAMC1/AHNAK	4
GO:0005539	glycosaminoglycan binding	18/571	230/18367	0.000322392328786021	0.00686235099844531	FN1/FBN1/APOE/AOC1/PPIA/PRG2/FSTL1/SERPINE2/PTPRF/ADGRG1/GNS/RPL29/NRP1/ENG/PDCD5/APLP2/APP/GPNMB	18
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	8/571	57/18367	0.000358712223189214	0.00742335017433235	QSOX1/PRDX3/TXN/GSTO1/GLRX/GLRX3/P4HB/PCYOX1	8
GO:0098631	cell adhesion mediator activity	8/571	59/18367	0.000455927594320796	0.0091801637234863	ANXA1/RPSA/PPP1CA/BCAM/ITGB1/DSC2/KRT18/DSG2	8
GO:0042277	peptide binding	22/571	321/18367	0.000476680726391548	0.00934545108320271	CD74/APOE/HLA-B/HLA-C/HLA-DRB1/HSP90AB1/HLA-DPA1/HLA-A/HLA-DRA/HLA-DPB1/PPIA/ITM2B/LRP1/PPIH/CLSTN1/PFDN4/PRLR/SLC40A1/MME/IGF1R/SEC61A1/CALR	22
GO:0004859	phospholipase inhibitor activity	4/571	13/18367	0.000528334169841692	0.00984022391330152	APOC1/ANXA1/ANXA5/ANXA3	4
GO:0005542	folic acid binding	4/571	13/18367	0.000528334169841692	0.00984022391330152	TYMS/SLC19A1/MTHFS/FOLR1	4
GO:0038024	cargo receptor activity	9/571	77/18367	0.00062634281623296	0.0113811072705745	LRP2/LRP1/ABCA1/LGALS3BP/COLEC12/OLR1/FOLR1/LRP10/TFRC	9
GO:1901681	sulfur compound binding	19/571	265/18367	0.000660875138622976	0.0117226661493837	FN1/FBN1/APOE/AOC1/PPIA/LRP1/PRG2/ACBD6/FSTL1/SERPINE2/GSTP1/PTPRF/ADGRG1/RPL29/NRP1/PDCD5/APLP2/APP/GPNMB	19
GO:0004553	hydrolase activity, hydrolyzing O-glycosyl compounds	10/571	94/18367	0.000676779464288065	0.0117255976952234	LYZ/GANAB/GAA/HEXB/NAGLU/MOGS/GLB1/EDEM3/HEXA/GM2A	10
GO:0043539	protein serine/threonine kinase activator activity	7/571	49/18367	0.000748161630614858	0.0126677367001834	CALM1/CKS1B/CCNB1/CKS2/IGF2/IQGAP1/DBF4	7
GO:0043394	proteoglycan binding	6/571	36/18367	0.000773697601937765	0.0128089936320808	FN1/APOE/LRP1/PTPRF/GPNMB/CTSB	6
GO:0061134	peptidase regulator activity	17/571	230/18367	0.000891881046154776	0.0144445952040284	FN1/GAPDH/CRIM1/SERPINE2/SERPINB1/PRDX3/BIRC5/SPINT1/PTTG1/PSMD14/APLP2/ITIH5/APP/SERPINF1/TIMP3/FBLN1/SERPINE1	17
GO:0005041	low-density lipoprotein particle receptor activity	4/571	15/18367	0.000959901189292322	0.0145944160412812	LRP2/LRP1/OLR1/LRP10	4
GO:0015929	hexosaminidase activity	4/571	15/18367	0.000959901189292322	0.0145944160412812	HEXB/NAGLU/HEXA/GM2A	4
GO:0050998	nitric-oxide synthase binding	4/571	15/18367	0.000959901189292322	0.0145944160412812	CD74/CALM1/ATP2B4/SLC6A4	4
GO:0005201	extracellular matrix structural constituent	14/571	172/18367	0.000987991770850517	0.0147210773856727	FN1/FBN2/FBN1/LAMA5/COL4A2/LAMC1/PRG2/COL4A1/SPARC/COL14A1/LAMB1/EFEMP1/FBLN1/COL21A1	14
GO:0002020	protease binding	12/571	135/18367	0.00104317685342187	0.0152385638392018	FN1/ADAMTSL4/LRP1/PSAP/PARK7/AMFR/ITGAV/ITGB1/DPP4/TIMP3/SRI/SERPINE1	12
GO:0097110	scaffold protein binding	8/571	67/18367	0.00107963353773378	0.0154678266463782	VIM/DYNLL1/ATP2B4/IL6ST/PSAP/PARK7/KRT8/KRT18	8
GO:0061135	endopeptidase regulator activity	15/571	194/18367	0.00111842934129186	0.0157213180992913	GAPDH/CRIM1/SERPINE2/SERPINB1/PRDX3/BIRC5/SPINT1/PTTG1/PSMD14/APLP2/ITIH5/APP/SERPINF1/TIMP3/SERPINE1	15
GO:0016684	oxidoreductase activity, acting on peroxide as acceptor	7/571	55/18367	0.00150575528083465	0.0206985116743301	PRDX1/GSTP1/PRDX3/GPX1/PARK7/HBA2/HBB	7
GO:0004866	endopeptidase inhibitor activity	14/571	180/18367	0.00152807804307135	0.0206985116743301	GAPDH/CRIM1/SERPINE2/SERPINB1/PRDX3/BIRC5/SPINT1/PTTG1/APLP2/ITIH5/APP/SERPINF1/TIMP3/SERPINE1	14
GO:0034185	apolipoprotein binding	4/571	17/18367	0.00159297563605	0.0211922651581652	LRP1/HSPD1/ABCA1/CANX	4
GO:0015036	disulfide oxidoreductase activity	6/571	42/18367	0.00178026950268529	0.0232684347280797	QSOX1/TXN/GSTO1/GLRX/GLRX3/P4HB	6
GO:0009055	electron transfer activity	11/571	126/18367	0.00192416797893483	0.0247156059363181	CYBA/UQCRH/CYCS/ETFB/COX4I1/NDUFB3/COX7A2L/SDHB/NDUFA10/COX5A/NDUFS3	11
GO:0030228	lipoprotein particle receptor activity	4/571	18/18367	0.00199820744704649	0.0248110758008272	LRP2/LRP1/OLR1/LRP10	4
GO:0055102	lipase inhibitor activity	4/571	18/18367	0.00199820744704649	0.0248110758008272	APOC1/ANXA1/ANXA5/ANXA3	4
GO:0030414	peptidase inhibitor activity	14/571	187/18367	0.00218431509418565	0.0266772909043985	GAPDH/CRIM1/SERPINE2/SERPINB1/PRDX3/BIRC5/SPINT1/PTTG1/APLP2/ITIH5/APP/SERPINF1/TIMP3/SERPINE1	14
GO:0140318	protein transporter activity	5/571	31/18367	0.00248162954536674	0.0298195808273907	LRP2/TOMM22/ABCA1/IGF1R/SEC61A1	5
GO:0032395	MHC class II receptor activity	3/571	10/18367	0.00304610248264558	0.0360213706281105	HLA-DRB1/HLA-DPA1/HLA-DRA	3
GO:0004867	serine-type endopeptidase inhibitor activity	9/571	98/18367	0.00344450439856066	0.0400961840144951	CRIM1/SERPINE2/SERPINB1/SPINT1/APLP2/ITIH5/APP/SERPINF1/SERPINE1	9
GO:0015026	coreceptor activity	6/571	48/18367	0.00356029667991347	0.0408064773313159	LRP1/ITGAV/NRP1/ITGB1/ENG/LRP5	6
GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	3/571	11/18367	0.00409229538299616	0.0452572700578696	QSOX1/P4HB/PCYOX1	3
GO:0042608	T cell receptor binding	3/571	11/18367	0.00409229538299616	0.0452572700578696	HLA-DRB1/HLA-A/HLA-DRA	3
GO:0019955	cytokine binding	11/571	139/18367	0.00413086491803373	0.0452572700578696	CD74/HMGB1/CSF3R/IL6ST/PARK7/ITGAV/NRP1/ITGB1/ENG/PRLR/COPS5	11
GO:0070034	telomerase RNA binding	4/571	22/18367	0.00432914106511787	0.0459191789263726	HNRNPC/NHP2/SNRPB/SNRPD3	4
GO:0070182	DNA polymerase binding	4/571	22/18367	0.00432914106511787	0.0459191789263726	HMGB1/HSP90AB1/PTGES3/RAD51	4
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	6/571	50/18367	0.00437619020640598	0.0459191789263726	CKS1B/CCNB1/CCNE1/CKS2/CCNB2/CCNA2	6
GO:0019887	protein kinase regulator activity	14/571	204/18367	0.00478438141928063	0.0463049281210811	NPM1/HMGB1/CALM1/HSP90AB1/CKS1B/PKIB/CCNB1/CCNE1/CKS2/CCNB2/CCNA2/IGF2/IQGAP1/DBF4	14
GO:0005200	structural constituent of cytoskeleton	9/571	103/18367	0.00479588239531733	0.0463049281210811	KRT19/VIM/HLA-DRB1/ACTG1/TUBA1B/TUBB4B/TUBA1C/ARPC2/ARPC5	9
GO:0004601	peroxidase activity	6/571	51/18367	0.00483223395245201	0.0463049281210811	PRDX1/GSTP1/PRDX3/GPX1/HBA2/HBB	6
GO:0016860	intramolecular oxidoreductase activity	6/571	51/18367	0.00483223395245201	0.0463049281210811	MIF/TPI1/QSOX1/PTGES3/ECH1/P4HB	6
GO:0042162	telomeric DNA binding	5/571	36/18367	0.00484803274287829	0.0463049281210811	HNRNPA1/NCL/HNRNPD/HNRNPA2B1/SMG1	5
GO:0061631	ubiquitin conjugating enzyme activity	5/571	36/18367	0.00484803274287829	0.0463049281210811	UBE2L3/UBE2N/UBE2T/UBE2D2/UBE2S	5
GO:0097718	disordered domain specific binding	5/571	36/18367	0.00484803274287829	0.0463049281210811	FN1/GAPDH/CALM1/HSP90AB1/GJA1	5
GO:0017134	fibroblast growth factor binding	4/571	23/18367	0.00511356135121393	0.0476200400831797	RPS2/RPS19/ITGAV/GLG1	4
GO:0030215	semaphorin receptor binding	4/571	23/18367	0.00511356135121393	0.0476200400831797	SEMA6D/SEMA3F/PLXNB1/SEMA6A	4
GO:0016798	hydrolase activity, acting on glycosyl bonds	11/571	144/18367	0.00538640930430608	0.0495408775679965	LYZ/GANAB/GAA/HEXB/DNPH1/NAGLU/MOGS/GLB1/EDEM3/HEXA/GM2A	11
GO:0015035	protein-disulfide reductase activity	5/571	37/18367	0.0054649910697802	0.0495408775679965	QSOX1/TXN/GLRX/GLRX3/P4HB	5
GO:0005518	collagen binding	7/571	69/18367	0.00551931924583049	0.0495408775679965	FN1/SPARC/ADGRG1/COL14A1/ITGB1/P3H1/CTSB	7
GO:0003727	single-stranded RNA binding	8/571	87/18367	0.00564353635570125	0.0500527926785409	HNRNPF/HNRNPA1/HMGB1/ANXA1/HNRNPC/SSB/EIF4A3/DAZAP1	8
GO:0019207	kinase regulator activity	15/571	233/18367	0.00640097356041606	0.0561026506177643	NPM1/HMGB1/CALM1/HSP90AB1/CKS1B/GSTP1/PKIB/CCNB1/CCNE1/CKS2/CCNB2/CCNA2/IGF2/IQGAP1/DBF4	15
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	3/571	13/18367	0.00677233102759874	0.0579929496041501	PRDX3/TXN/GLRX	3
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	3/571	13/18367	0.00677233102759874	0.0579929496041501	CKS1B/CCNB1/CKS2	3
GO:0061650	ubiquitin-like protein conjugating enzyme activity	5/571	39/18367	0.00686148528051102	0.0580887106134172	UBE2L3/UBE2N/UBE2T/UBE2D2/UBE2S	5
GO:0015453	oxidoreduction-driven active transmembrane transporter activity	7/571	72/18367	0.00696137530029539	0.0582721865024727	UQCRH/COX4I1/NDUFB3/COX7A2L/NDUFA10/COX5A/NDUFS3	7
GO:0140104	molecular carrier activity	7/571	73/18367	0.00749903480902645	0.0620753436969412	RAN/NUTF2/PARK7/HBA2/TIMM9/HBB/EMC1	7
GO:0003725	double-stranded RNA binding	7/571	74/18367	0.00806678259482321	0.0660412421224537	VIM/HMGB1/HSP90AB1/TUBA1B/TUBB4B/HSPD1/TFRC	7
GO:0015926	glucosidase activity	3/571	14/18367	0.00842253947528019	0.067470880742836	GANAB/GAA/MOGS	3
GO:0044548	S100 protein binding	3/571	14/18367	0.00842253947528019	0.067470880742836	CACYBP/AHNAK/IQGAP1	3
GO:0022884	macromolecule transmembrane transporter activity	4/571	27/18367	0.00919021760664275	0.0720706538626195	HNRNPA3/TOMM22/ABCA1/SEC61A1	4
GO:0045499	chemorepellent activity	4/571	27/18367	0.00919021760664275	0.0720706538626195	SEMA6D/SEMA3F/DPP4/SEMA6A	4
GO:0019215	intermediate filament binding	3/571	15/18367	0.0102881990467772	0.0782113090800918	VIM/NME1/NME2	3
GO:0032794	GTPase activating protein binding	3/571	15/18367	0.0102881990467772	0.0782113090800918	CDH1/PLXNB1/GNAI3	3
GO:1990825	sequence-specific mRNA binding	3/571	15/18367	0.0102881990467772	0.0782113090800918	SRSF3/TYMS/SSB	3
GO:0070325	lipoprotein particle receptor binding	4/571	28/18367	0.0104636285189511	0.0787414469355411	APOE/DNAJA1/LRP1/HSP90B1	4
GO:0030246	carbohydrate binding	16/571	271/18367	0.0109764953630927	0.0817748904550409	LGALS1/HLA-DRB1/ALDOA/HLA-DRA/PRG2/UGP2/GANAB/ENG/LMAN1/COLEC12/GALNT11/GAA/OLR1/CANX/P3H1/CALR	16
GO:0017070	U6 snRNA binding	3/571	16/18367	0.0123742569373132	0.0912754595871124	LSM3/LSM4/LSM8	3
GO:0030295	protein kinase activator activity	8/571	101/18367	0.0134266978518316	0.098067548035437	HMGB1/CALM1/CKS1B/CCNB1/CKS2/IGF2/IQGAP1/DBF4	8
GO:0000400	four-way junction DNA binding	3/571	17/18367	0.0146845315018696	0.10407921484416	HMGB2/HMGB1/HMGB3	3
GO:0043024	ribosomal small subunit binding	3/571	17/18367	0.0146845315018696	0.10407921484416	NPM1/NME1/EIF1	3
GO:0031210	phosphatidylcholine binding	4/571	31/18367	0.0149482899172149	0.10407921484416	APOC1/VDAC2/VDAC1/ABCA1	4
GO:0071813	lipoprotein particle binding	4/571	31/18367	0.0149482899172149	0.10407921484416	APOE/HSPD1/ABCA1/COLEC12	4
GO:0071814	protein-lipid complex binding	4/571	31/18367	0.0149482899172149	0.10407921484416	APOE/HSPD1/ABCA1/COLEC12	4
GO:0008022	protein C-terminus binding	12/571	189/18367	0.0153332651475467	0.105771134582614	FN1/NCL/YWHAQ/MAD2L1/BANF1/PRDX3/BCAM/ITGB3BP/RAD51/CDC20/FBLN1/MKI67	12
GO:0008301	DNA binding, bending	3/571	18/18367	0.0172217963128342	0.115587732009563	HMGB2/HMGB1/HMGB3	3
GO:0070122	isopeptidase activity	3/571	18/18367	0.0172217963128342	0.115587732009563	EIF3H/PSMD14/COPS5	3
GO:0098641	cadherin binding involved in cell-cell adhesion	3/571	18/18367	0.0172217963128342	0.115587732009563	ANXA1/PPP1CA/KRT18	3
GO:0098632	cell-cell adhesion mediator activity	5/571	49/18367	0.0176589074620468	0.117463268385936	ANXA1/PPP1CA/DSC2/KRT18/DSG2	5
GO:0019209	kinase activator activity	8/571	107/18367	0.0184622508081938	0.121720149133667	HMGB1/CALM1/CKS1B/CCNB1/CKS2/IGF2/IQGAP1/DBF4	8
GO:0004129	cytochrome-c oxidase activity	3/571	19/18367	0.0199878595208692	0.130622415289891	COX4I1/COX7A2L/COX5A	3
GO:0035198	miRNA binding	4/571	34/18367	0.0204869908140648	0.132720070925898	NEAT1/YBX1/HNRNPA1/HNRNPA2B1	4
GO:0008047	enzyme activator activity	8/571	110/18367	0.0214313551403199	0.136464611790926	APOC1/APOE/CALM1/PSAP/PARK7/PDCD5/DBF4/GM2A	8
GO:0047485	protein N-terminus binding	8/571	110/18367	0.0214313551403199	0.136464611790926	NPM1/CALM1/EIF3E/YWHAQ/BANF1/ZWINT/PDCD10/GLRX	8
GO:0031491	nucleosome binding	6/571	71/18367	0.0229202673112954	0.141445097954432	HMGN2/HMGN1/HNRNPC/SUPT16H/VRK1/SMARCA1	6
GO:0048029	monosaccharide binding	6/571	71/18367	0.0229202673112954	0.141445097954432	ALDOA/UGP2/ENG/LMAN1/COLEC12/P3H1	6
GO:0016675	oxidoreductase activity, acting on a heme group of donors	3/571	20/18367	0.0229836387464887	0.141445097954432	COX4I1/COX7A2L/COX5A	3
GO:0097001	ceramide binding	3/571	20/18367	0.0229836387464887	0.141445097954432	VDAC2/VDAC1/PSAP	3
GO:0044325	transmembrane transporter binding	9/571	133/18367	0.0231628214099876	0.141445097954432	CALM1/HSP90AB1/VDAC1/YWHAQ/PHPT1/S100A10/BAG2/AKAP9/SRI	9
GO:0043130	ubiquitin binding	7/571	92/18367	0.0244865509884298	0.148312849482766	CKS1B/UBE2N/BUB3/AMFR/CKS2/UBXN1/UCHL3	7
GO:0000217	DNA secondary structure binding	4/571	36/18367	0.0247941757595253	0.14896500758747	HMGB2/HMGB1/HMGB3/HNRNPD	4
GO:0072341	modified amino acid binding	7/571	93/18367	0.0257978656914907	0.153755279521284	HMGB1/TYMS/SLC19A1/MTHFS/SCIN/MME/FOLR1	7
GO:0015399	primary active transmembrane transporter activity	11/571	181/18367	0.0262680178699555	0.155314867564419	ATP2B4/UQCRH/SLC26A2/COX4I1/NDUFB3/COX7A2L/NDUFA10/ABCA1/COX5A/NDUFS3/ATP2B1	11
GO:0042056	chemoattractant activity	4/571	37/18367	0.0271371072370701	0.159190117256829	MIF/HMGB2/HMGB1/GPNMB	4
GO:0008320	protein transmembrane transporter activity	3/571	22/18367	0.0296639828757381	0.172653650331444	TOMM22/ABCA1/SEC61A1	3
GO:0050997	quaternary ammonium group binding	4/571	39/18367	0.0322074897748522	0.186004495211356	APOC1/VDAC2/VDAC1/ABCA1	4
GO:0005158	insulin receptor binding	3/571	23/18367	0.0333465461044167	0.188205885210534	SNX2/IGF2/IGF1R	3
GO:0017116	single-stranded DNA helicase activity	3/571	23/18367	0.0333465461044167	0.188205885210534	RFC2/RFC3/RAD51	3
GO:0050750	low-density lipoprotein particle receptor binding	3/571	23/18367	0.0333465461044167	0.188205885210534	APOE/DNAJA1/HSP90B1	3
GO:0019199	transmembrane receptor protein kinase activity	9/571	143/18367	0.0347315623902898	0.194548977298992	CRIM1/FLT1/EGFR/MET/NRP1/ENG/PBK/EFEMP1/IGF1R	9
GO:0016835	carbon-oxygen lyase activity	6/571	79/18367	0.0362562853645942	0.195819176014923	RPS3/TPI1/ENO1/PARK7/ECHS1/FH	6
GO:0008097	5S rRNA binding	2/571	10/18367	0.0367982344189118	0.195819176014923	RPL5/RPL11	2
GO:0030957	Tat protein binding	2/571	10/18367	0.0367982344189118	0.195819176014923	NPM1/DNAJA1	2
GO:0031720	haptoglobin binding	2/571	10/18367	0.0367982344189118	0.195819176014923	HBA2/HBB	2
GO:0050786	RAGE receptor binding	2/571	10/18367	0.0367982344189118	0.195819176014923	HMGB2/HMGB1	2
GO:0097027	ubiquitin-protein transferase activator activity	2/571	10/18367	0.0367982344189118	0.195819176014923	UBE2L3/CDC20	2
GO:0098505	G-rich strand telomeric DNA binding	2/571	10/18367	0.0367982344189118	0.195819176014923	HNRNPA1/HNRNPA2B1	2
GO:0030020	extracellular matrix structural constituent conferring tensile strength	4/571	41/18367	0.0377956880067865	0.199700621028766	COL4A2/COL4A1/COL14A1/COL21A1	4
GO:0051015	actin filament binding	12/571	217/18367	0.0391754041136539	0.205532930032903	EGFR/SLC6A4/MARCKS/ARPC2/ARPC5/CFL1/ARPC1A/FRG1/AIF1/IQGAP1/MACF1/SCIN	12
GO:0004714	transmembrane receptor protein tyrosine kinase activity	8/571	124/18367	0.039794367643358	0.207320306953159	CRIM1/FLT1/EGFR/MET/NRP1/PBK/EFEMP1/IGF1R	8
GO:0008266	poly(U) RNA binding	3/571	25/18367	0.0413866227006623	0.213177497072379	HNRNPC/SSB/DAZAP1	3
GO:0016504	peptidase activator activity	4/571	43/18367	0.0439047778493287	0.213177497072379	FN1/PSMD14/APP/FBLN1	4
GO:0000774	adenyl-nucleotide exchange factor activity	2/571	11/18367	0.0440662208713374	0.213177497072379	PFN1/BAG2	2
GO:0008199	ferric iron binding	2/571	11/18367	0.0440662208713374	0.213177497072379	FTL/RRM2	2
GO:0019855	calcium channel inhibitor activity	2/571	11/18367	0.0440662208713374	0.213177497072379	CALM1/PHPT1	2
GO:0022889	serine transmembrane transporter activity	2/571	11/18367	0.0440662208713374	0.213177497072379	SLC38A2/SLC1A5	2
GO:0047134	protein-disulfide reductase (NAD(P)) activity	2/571	11/18367	0.0440662208713374	0.213177497072379	TXN/GLRX	2
GO:0047429	nucleoside-triphosphate diphosphatase activity	2/571	11/18367	0.0440662208713374	0.213177497072379	DUT/NUDT15	2
GO:0086080	protein binding involved in heterotypic cell-cell adhesion	2/571	11/18367	0.0440662208713374	0.213177497072379	DSC2/DSG2	2
GO:1901612	cardiolipin binding	2/571	11/18367	0.0440662208713374	0.213177497072379	STOML2/MME	2
GO:1990226	histone methyltransferase binding	2/571	11/18367	0.0440662208713374	0.213177497072379	HSP90AB1/CBX1	2
GO:0140677	molecular function activator activity	9/571	150/18367	0.044871722010253	0.215673760629926	APOC1/APOE/CALM1/DNAJA1/PSAP/PARK7/PDCD5/DBF4/GM2A	9
GO:0015631	tubulin binding	18/571	375/18367	0.0462618554737543	0.220930014922737	GAPDH/RPS3/ALDOA/STMN1/CCT5/NME1/CACYBP/BIRC5/SKA2/DAG1/BEX4/GABARAP/PDCD5/MACF1/HAUS8/GJA1/TUBGCP2/CLIP1	18
GO:0001540	amyloid-beta binding	6/571	84/18367	0.0466890891099228	0.221550136222245	CD74/APOE/ITM2B/LRP1/CLSTN1/PFDN4	6
GO:0003730	mRNA 3'-UTR binding	11/571	201/18367	0.0499445636272215	0.235498100647342	RPL5/YBX3/RPL41/CCT5/HNRNPC/HNRNPD/CIRBP/HNRNPA2B1/RSL1D1/DAZAP1/EXOSC9	11
GO:0048156	tau protein binding	4/571	45/18367	0.0505344923464942	0.236781111937976	APOE/HSP90AB1/LGMN/BAG2	4
GO:0042562	hormone binding	6/571	86/18367	0.0513323633750579	0.236814856234848	LRP2/EGFR/PRLR/SLC40A1/IGF1R/CALR	6
GO:0031543	peptidyl-proline dioxygenase activity	2/571	12/18367	0.0518131833104432	0.236814856234848	P3H1/P4HB	2
GO:0043047	single-stranded telomeric DNA binding	2/571	12/18367	0.0518131833104432	0.236814856234848	HNRNPA1/HNRNPA2B1	2
GO:0045295	gamma-catenin binding	2/571	12/18367	0.0518131833104432	0.236814856234848	CDH1/DSC3	2
GO:0061980	regulatory RNA binding	4/571	46/18367	0.0540436363731306	0.245503104255989	NEAT1/YBX1/HNRNPA1/HNRNPA2B1	4
GO:0001968	fibronectin binding	3/571	28/18367	0.0550882513738263	0.245752977685632	ITGAV/ITGB1/FBLN1	3
GO:0003785	actin monomer binding	3/571	28/18367	0.0550882513738263	0.245752977685632	PFN1/TMSB10/TMSB4X	3
GO:0008187	poly-pyrimidine tract binding	3/571	28/18367	0.0550882513738263	0.245752977685632	HNRNPC/SSB/DAZAP1	3
GO:0048306	calcium-dependent protein binding	6/571	88/18367	0.0562480244274586	0.249433203562242	CALM1/ANXA1/ATP2B4/S100A10/ANXA3/S100P	6
GO:0032182	ubiquitin-like protein binding	7/571	111/18367	0.0580063424842172	0.251449095154812	CKS1B/UBE2N/BUB3/AMFR/CKS2/UBXN1/UCHL3	7
GO:0016853	isomerase activity	9/571	158/18367	0.0586811203580035	0.251449095154812	MIF/TPI1/QSOX1/PPIA/PTGES3/HSPD1/PPIH/ECH1/P4HB	9
GO:0008035	high-density lipoprotein particle binding	2/571	13/18367	0.0600024291800513	0.251449095154812	HSPD1/ABCA1	2
GO:0008271	secondary active sulfate transmembrane transporter activity	2/571	13/18367	0.0600024291800513	0.251449095154812	SLC26A2/SLC13A4	2
GO:0031386	protein tag	2/571	13/18367	0.0600024291800513	0.251449095154812	RPS27A/SUMO2	2
GO:0034450	ubiquitin-ubiquitin ligase activity	2/571	13/18367	0.0600024291800513	0.251449095154812	AMFR/ANAPC11	2
GO:0051011	microtubule minus-end binding	2/571	13/18367	0.0600024291800513	0.251449095154812	MACF1/TUBGCP2	2
GO:0060590	ATPase regulator activity	2/571	13/18367	0.0600024291800513	0.251449095154812	PFN1/BAG2	2
GO:0015301	anion:anion antiporter activity	3/571	29/18367	0.060077770385982	0.251449095154812	SLC25A5/SLC26A2/SLC19A1	3
GO:0046625	sphingolipid binding	3/571	29/18367	0.060077770385982	0.251449095154812	VDAC2/VDAC1/PSAP	3
GO:0004713	protein tyrosine kinase activity	8/571	136/18367	0.06212005288477	0.258544354185216	CRIM1/FLT1/EGFR/MET/NRP1/PBK/EFEMP1/IGF1R	8
GO:0005310	dicarboxylic acid transmembrane transporter activity	3/571	30/18367	0.0652708905867675	0.268656428105756	SLC26A2/SLC19A1/SLC1A5	3
GO:0022829	wide pore channel activity	3/571	30/18367	0.0652708905867675	0.268656428105756	VDAC2/VDAC1/GJA1	3
GO:0004298	threonine-type endopeptidase activity	2/571	14/18367	0.0685990774641798	0.271842088887308	PSMA4/PSMB1	2
GO:0005344	oxygen carrier activity	2/571	14/18367	0.0685990774641798	0.271842088887308	HBA2/HBB	2
GO:0015373	anion:sodium symporter activity	2/571	14/18367	0.0685990774641798	0.271842088887308	SLC6A4/SLC13A4	2
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	2/571	14/18367	0.0685990774641798	0.271842088887308	MIF/ECH1	2
GO:0032977	membrane insertase activity	2/571	14/18367	0.0685990774641798	0.271842088887308	TIMM9/EMC1	2
GO:0043023	ribosomal large subunit binding	2/571	14/18367	0.0685990774641798	0.271842088887308	NPM1/MALSU1	2
GO:0140666	annealing activity	2/571	14/18367	0.0685990774641798	0.271842088887308	ANXA1/SMARCA1	2
GO:0090482	vitamin transmembrane transporter activity	3/571	31/18367	0.0706625978013625	0.278537753238175	SLC2A1/SLC19A1/SLC52A1	3
GO:0003678	DNA helicase activity	5/571	72/18367	0.0732093206514131	0.28705759939633	ANXA1/RFC2/RFC3/RAD51/RUVBL1	5
GO:0001846	opsonin binding	2/571	15/18367	0.0775699818360879	0.299428168227386	ITGAV/CALR	2
GO:0098847	sequence-specific single stranded DNA binding	2/571	15/18367	0.0775699818360879	0.299428168227386	HNRNPA1/HNRNPA2B1	2
GO:1901611	phosphatidylglycerol binding	2/571	15/18367	0.0775699818360879	0.299428168227386	STOML2/MME	2
GO:0140375	immune receptor activity	8/571	144/18367	0.0806344172308484	0.309652787819495	CD74/HLA-DRB1/CSF3R/FCER1G/HLA-DPA1/HLA-DRA/IL6ST/PRLR	8
GO:0019956	chemokine binding	3/571	33/18367	0.0820203988860784	0.310665314221044	HMGB1/ITGAV/ITGB1	3
GO:0140323	solute:anion antiporter activity	3/571	33/18367	0.0820203988860784	0.310665314221044	SLC25A5/SLC26A2/SLC19A1	3
GO:0017069	snRNA binding	4/571	53/18367	0.082149083089323	0.310665314221044	LSM3/LSM4/LSM8/SNRPD3	4
GO:0035173	histone kinase activity	2/571	16/18367	0.0868836568216271	0.326910728950062	CDK1/VRK1	2
GO:0003779	actin binding	19/571	440/18367	0.0943156144593524	0.349029631620751	PFN1/ALDOA/TMSB10/EGFR/SLC6A4/MARCKS/ARPC2/ARPC5/CFL1/TMSB4X/ARPC1A/ITGB1/DAG1/FRG1/AIF1/IQGAP1/MACF1/SCIN/P4HB	19
GO:0051287	NAD binding	4/571	56/18367	0.0960132763013928	0.349029631620751	GAPDH/LDHA/MDH1/HPGD	4
GO:0005324	long-chain fatty acid transporter activity	2/571	17/18367	0.0965102068642614	0.349029631620751	SLC2A1/SLC27A2	2
GO:0008308	voltage-gated anion channel activity	2/571	17/18367	0.0965102068642614	0.349029631620751	VDAC2/VDAC1	2
GO:0008484	sulfuric ester hydrolase activity	2/571	17/18367	0.0965102068642614	0.349029631620751	GNS/STS	2
GO:0015116	sulfate transmembrane transporter activity	2/571	17/18367	0.0965102068642614	0.349029631620751	SLC26A2/SLC13A4	2
GO:0043395	heparan sulfate proteoglycan binding	2/571	17/18367	0.0965102068642614	0.349029631620751	APOE/LRP1	2
GO:0070628	proteasome binding	2/571	17/18367	0.0965102068642614	0.349029631620751	PSMG1/PSMD14	2
GO:0031406	carboxylic acid binding	9/571	176/18367	0.0988683703312236	0.355830608196916	APOC1/TYMS/GSTP1/PSAP/SLC19A1/MTHFS/NME2/FOLR1/P3H1	9
GO:0140097	catalytic activity, acting on DNA	11/571	229/18367	0.102448875981616	0.366944291376461	RPS3/ANXA1/NME1/PTGES3/POLE3/RFC2/RFC3/RAD51/SMARCA1/RUVBL1/PLD3	11
GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups	4/571	58/18367	0.105825229563759	0.368762034169658	GSTP1/SMS/GSTO1/NANS	4
GO:0000295	adenine nucleotide transmembrane transporter activity	2/571	18/18367	0.10642125818319	0.368762034169658	SLC25A5/SLC19A1	2
GO:0004550	nucleoside diphosphate kinase activity	2/571	18/18367	0.10642125818319	0.368762034169658	NME1/NME2	2
GO:0005346	purine ribonucleotide transmembrane transporter activity	2/571	18/18367	0.10642125818319	0.368762034169658	SLC25A5/SLC19A1	2
GO:0046624	sphingolipid transporter activity	2/571	18/18367	0.10642125818319	0.368762034169658	ATP10D/ABCA1	2
GO:0048038	quinone binding	2/571	18/18367	0.10642125818319	0.368762034169658	AOC1/SDHB	2
GO:0140597	protein carrier activity	2/571	18/18367	0.10642125818319	0.368762034169658	TIMM9/EMC1	2
GO:0031072	heat shock protein binding	7/571	129/18367	0.107711938622947	0.371506454972664	RPS3/HSP90AB1/DNAJA1/DNAJC9/PTGES3/HSPA9/BAG2	7
GO:0015175	neutral amino acid transmembrane transporter activity	3/571	38/18367	0.113495027843468	0.389273896916438	SLC38A2/SLC43A2/SLC1A5	3
GO:0004386	helicase activity	8/571	156/18367	0.113908334936622	0.389273896916438	ANXA1/EIF4A3/RFC2/RFC3/RAD51/DDX24/SMARCA1/RUVBL1	8
GO:0003746	translation elongation factor activity	2/571	19/18367	0.116589893319933	0.394815775106138	EEF1B2/EEF1A1	2
GO:0035613	RNA stem-loop binding	2/571	19/18367	0.116589893319933	0.394815775106138	EIF4A3/DAZAP1	2
GO:0005504	fatty acid binding	3/571	39/18367	0.120268989349186	0.402857409388191	APOC1/GSTP1/NME2	3
GO:0019825	oxygen binding	3/571	39/18367	0.120268989349186	0.402857409388191	PARK7/HBA2/HBB	3
GO:0030165	PDZ domain binding	5/571	84/18367	0.120586848716197	0.402857409388191	CRIM1/ATP2B4/GJA1/ATP2B1/ADRB1	5
GO:0001091	RNA polymerase II general transcription initiation factor binding	2/571	20/18367	0.126990588272538	0.411977979559262	RUVBL1/GTF2F1	2
GO:0003756	protein disulfide isomerase activity	2/571	20/18367	0.126990588272538	0.411977979559262	QSOX1/P4HB	2
GO:0016018	cyclosporin A binding	2/571	20/18367	0.126990588272538	0.411977979559262	PPIA/PPIH	2
GO:0016500	protein-hormone receptor activity	2/571	20/18367	0.126990588272538	0.411977979559262	LGR5/IGF1R	2
GO:0016864	intramolecular oxidoreductase activity, transposing S-S bonds	2/571	20/18367	0.126990588272538	0.411977979559262	QSOX1/P4HB	2
GO:0019211	phosphatase activator activity	2/571	20/18367	0.126990588272538	0.411977979559262	CALM1/GTF2F1	2
GO:0031492	nucleosomal DNA binding	3/571	40/18367	0.127187832615611	0.411977979559262	HMGN2/HMGN1/HNRNPC	3
GO:0043177	organic acid binding	7/571	135/18367	0.128140985925582	0.413268547682073	TYMS/HBA2/SLC19A1/MTHFS/HBB/FOLR1/P3H1	7
GO:0022853	active ion transmembrane transporter activity	12/571	267/18367	0.129800976562511	0.416817791116685	ATP2B4/SLC25A5/UQCRH/SLC26A2/SLC6A4/COX4I1/SLC19A1/SLC38A2/COX7A2L/COX5A/ATP2B1/SLC13A4	12
GO:0008094	ATP-dependent activity, acting on DNA	6/571	111/18367	0.132144257963358	0.421986262816864	ANXA1/RFC2/RFC3/RAD51/SMARCA1/RUVBL1	6
GO:0022804	active transmembrane transporter activity	17/571	406/18367	0.132543336240465	0.421986262816864	ATP2B4/SLC25A5/UQCRH/SLC26A2/SLC6A4/COX4I1/NDUFB3/SLC19A1/SLC38A2/COX7A2L/NDUFA10/ABCA1/COX5A/NDUFS3/ATP2B1/SLC13A4/SLC1A5	17
GO:0048487	beta-tubulin binding	3/571	41/18367	0.134245107189992	0.425585552581038	CCT5/GABARAP/PDCD5	3
GO:0015216	purine nucleotide transmembrane transporter activity	2/571	21/18367	0.137599152120201	0.427713839713938	SLC25A5/SLC19A1	2
GO:0015662	P-type ion transporter activity	2/571	21/18367	0.137599152120201	0.427713839713938	ATP2B4/ATP2B1	2
GO:0140358	P-type transmembrane transporter activity	2/571	21/18367	0.137599152120201	0.427713839713938	ATP2B4/ATP2B1	2
GO:1990381	ubiquitin-specific protease binding	2/571	21/18367	0.137599152120201	0.427713839713938	PARK7/AMFR	2
GO:0016836	hydro-lyase activity	4/571	64/18367	0.137787008766906	0.427713839713938	ENO1/PARK7/ECHS1/FH	4
GO:0008137	NADH dehydrogenase (ubiquinone) activity	3/571	42/18367	0.141434341425737	0.433615573506888	NDUFB3/NDUFA10/NDUFS3	3
GO:0008307	structural constituent of muscle	3/571	42/18367	0.141434341425737	0.433615573506888	KRT19/CSRP2/DAG1	3
GO:0019205	nucleobase-containing compound kinase activity	3/571	42/18367	0.141434341425737	0.433615573506888	NME1/TK1/NME2	3
GO:0051117	ATPase binding	5/571	89/18367	0.143707032267813	0.43877761901443	EGFR/ABCA1/UBXN1/RUVBL1/PIH1D1	5
GO:0046982	protein heterodimerization activity	14/571	328/18367	0.144913126716869	0.439383763962715	RAN/LSM6/CYBA/TRMT112/SNX2/KRT10/LSM5/POLE3/TENM3/ITGB1/SRI/P4HB/ADRB1/HEXA	14
GO:0004602	glutathione peroxidase activity	2/571	22/18367	0.148392669044647	0.439383763962715	GSTP1/GPX1	2
GO:0015296	anion:cation symporter activity	2/571	22/18367	0.148392669044647	0.439383763962715	SLC6A4/SLC13A4	2
GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	2/571	22/18367	0.148392669044647	0.439383763962715	PRDX3/BIRC5	2
GO:0072349	modified amino acid transmembrane transporter activity	2/571	22/18367	0.148392669044647	0.439383763962715	SLC19A1/GJA1	2
GO:0120020	cholesterol transfer activity	2/571	22/18367	0.148392669044647	0.439383763962715	APOE/ABCA1	2
GO:0005246	calcium channel regulator activity	3/571	43/18367	0.148749058693968	0.439383763962715	CALM1/PHPT1/SRI	3
GO:0050136	NADH dehydrogenase (quinone) activity	3/571	43/18367	0.148749058693968	0.439383763962715	NDUFB3/NDUFA10/NDUFS3	3
GO:0043022	ribosome binding	4/571	66/18367	0.149213546688009	0.439383763962715	RPSA/SRP19/EIF2A/SEC61A1	4
GO:0008375	acetylglucosaminyltransferase activity	3/571	44/18367	0.156182792344667	0.458095198018807	HEXB/B3GNT3/HEXA	3
GO:0016829	lyase activity	9/571	196/18367	0.158208316444009	0.462216453924653	RPS3/HMGB1/TPI1/ALDOA/ENO1/PARK7/UMPS/ECHS1/FH	9
GO:0120015	sterol transfer activity	2/571	23/18367	0.159349442658002	0.463731776485203	APOE/ABCA1	2
GO:0003684	damaged DNA binding	4/571	68/18367	0.160989272904975	0.466680966203137	RPS3/HMGB2/HMGB1/RPA3	4
GO:0003954	NADH dehydrogenase activity	3/571	45/18367	0.163729099487394	0.470958220533237	NDUFB3/NDUFA10/NDUFS3	3
GO:0003955	NAD(P)H dehydrogenase (quinone) activity	3/571	45/18367	0.163729099487394	0.470958220533237	NDUFB3/NDUFA10/NDUFS3	3
GO:0050431	transforming growth factor beta binding	2/571	24/18367	0.170448942550164	0.486530506512921	ITGAV/ENG	2
GO:0070003	threonine-type peptidase activity	2/571	24/18367	0.170448942550164	0.486530506512921	PSMA4/PSMB1	2
GO:0005044	scavenger receptor activity	3/571	47/18367	0.179133856435822	0.507432407014021	LRP1/LGALS3BP/COLEC12	3
GO:0035254	glutamate receptor binding	3/571	47/18367	0.179133856435822	0.507432407014021	CALM1/MYL12A/CANX	3
GO:0030247	polysaccharide binding	2/571	25/18367	0.18167175297186	0.510737569675607	HLA-DRB1/HLA-DRA	2
GO:0035925	mRNA 3'-UTR AU-rich region binding	2/571	25/18367	0.18167175297186	0.510737569675607	HNRNPD/EXOSC9	2
GO:0019903	protein phosphatase binding	7/571	150/18367	0.186780473195307	0.521722238992189	ATP2B4/EGFR/PPP1CA/MET/HSP90B1/IQGAP1/GTF2F1	7
GO:0120013	lipid transfer activity	3/571	48/18367	0.186979648068341	0.521722238992189	APOE/TRIAP1/ABCA1	3
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	6/571	124/18367	0.189279229576182	0.526168007590507	LDHA/MDH1/HPGD/LDHB/IMPDH2/MDH2	6
GO:0033293	monocarboxylic acid binding	4/571	73/18367	0.191802018013268	0.530570645983775	APOC1/GSTP1/PSAP/NME2	4
GO:0004364	glutathione transferase activity	2/571	26/18367	0.192999523572622	0.530570645983775	GSTP1/GSTO1	2
GO:0030371	translation repressor activity	2/571	26/18367	0.192999523572622	0.530570645983775	TYMS/CIRBP	2
GO:0003713	transcription coactivator activity	11/571	262/18367	0.194338097791301	0.532286334023969	NPM1/HMGB2/HMGB1/UBE2L3/SUB1/PARK7/VGLL1/RUVBL1/MED4/NME2/COPS5	11
GO:0051020	GTPase binding	12/571	291/18367	0.196930576516139	0.53741128023635	RANBP1/PFN1/YBX1/YBX3/ENO1/NUTF2/BIRC5/STOML2/ABCA1/BNIP3/IQGAP1/ATP6AP1	12
GO:0015485	cholesterol binding	3/571	50/18367	0.202926909517092	0.547802579051476	VDAC2/VDAC1/ABCA1	3
GO:0015932	nucleobase-containing compound transmembrane transporter activity	3/571	50/18367	0.202926909517092	0.547802579051476	SLC25A5/HNRNPA3/SLC19A1	3
GO:0005319	lipid transporter activity	7/571	154/18367	0.204030144283255	0.547802579051476	APOE/ATP10D/SLC2A1/TRIAP1/ABCA1/SLC27A2/GM2A	7
GO:0015215	nucleotide transmembrane transporter activity	2/571	27/18367	0.204414922115853	0.547802579051476	SLC25A5/SLC19A1	2
GO:0140326	ATPase-coupled intramembrane lipid transporter activity	2/571	27/18367	0.204414922115853	0.547802579051476	ATP10D/ABCA1	2
GO:0050681	androgen receptor binding	2/571	28/18367	0.215901589096009	0.576511411743822	PARK7/CALR	2
GO:0008514	organic anion transmembrane transporter activity	8/571	185/18367	0.219075827127054	0.579024779177664	SLC25A5/SLC2A1/SLC26A2/SLC19A1/SLC38A2/SLC52A1/GJA1/SLC1A5	8
GO:0017046	peptide hormone binding	3/571	52/18367	0.219174480171948	0.579024779177664	PRLR/SLC40A1/IGF1R	3
GO:1901682	sulfur compound transmembrane transporter activity	3/571	52/18367	0.219174480171948	0.579024779177664	SLC26A2/GJA1/SLC13A4	3
GO:0035250	UDP-galactosyltransferase activity	2/571	29/18367	0.22744409418564	0.596640317494021	B4GALT1/B3GNT3	2
GO:0070717	poly-purine tract binding	2/571	29/18367	0.22744409418564	0.596640317494021	EIF4A3/DAZAP1	2
GO:0005544	calcium-dependent phospholipid binding	3/571	54/18367	0.235674954393021	0.616062600080003	ANXA1/ANXA5/ANXA3	3
GO:0008234	cysteine-type peptidase activity	8/571	190/18367	0.240120326324691	0.623883945397626	EIF3H/LGMN/PSMD14/CTSD/UCHL3/CTSF/COPS5/CTSB	8
GO:0005080	protein kinase C binding	3/571	55/18367	0.244005668007636	0.623883945397626	MARCKS/ITGAV/GLRX3	3
GO:0046943	carboxylic acid transmembrane transporter activity	7/571	163/18367	0.244881019949349	0.623883945397626	SLC26A2/SLC19A1/SLC38A2/SLC38A10/SLC43A2/SLC27A2/SLC1A5	7
GO:0016614	oxidoreductase activity, acting on CH-OH group of donors	6/571	136/18367	0.248916040326502	0.623883945397626	LDHA/MDH1/HPGD/LDHB/IMPDH2/MDH2	6
GO:0005342	organic acid transmembrane transporter activity	7/571	164/18367	0.24957337683292	0.623883945397626	SLC26A2/SLC19A1/SLC38A2/SLC38A10/SLC43A2/SLC27A2/SLC1A5	7
GO:0042910	xenobiotic transmembrane transporter activity	2/571	31/18367	0.250639294211071	0.623883945397626	SLC2A1/SLC19A1	2
GO:0043015	gamma-tubulin binding	2/571	31/18367	0.250639294211071	0.623883945397626	NME1/TUBGCP2	2
GO:0140142	nucleocytoplasmic carrier activity	2/571	31/18367	0.250639294211071	0.623883945397626	RAN/NUTF2	2
GO:0004869	cysteine-type endopeptidase inhibitor activity	3/571	56/18367	0.252382595840064	0.623883945397626	PRDX3/BIRC5/PTTG1	3
GO:0004536	deoxyribonuclease activity	3/571	57/18367	0.260800307223552	0.623883945397626	RPS3/NME1/PLD3	3
GO:0016655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	3/571	57/18367	0.260800307223552	0.623883945397626	NDUFB3/NDUFA10/NDUFS3	3
GO:0008378	galactosyltransferase activity	2/571	32/18367	0.262265406649666	0.623883945397626	B4GALT1/B3GNT3	2
GO:0015605	organophosphate ester transmembrane transporter activity	2/571	32/18367	0.262265406649666	0.623883945397626	SLC25A5/SLC19A1	2
GO:0099106	ion channel regulator activity	6/571	139/18367	0.264607630110888	0.623883945397626	CALM1/ATP2B4/PHPT1/AKAP9/SRI/PRSS8	6
GO:0015171	amino acid transmembrane transporter activity	4/571	84/18367	0.26490415547814	0.623883945397626	SLC38A2/SLC38A10/SLC43A2/SLC1A5	4
GO:0001094	TFIID-class transcription factor complex binding	1/571	10/18367	0.270865650747294	0.623883945397626	RUVBL1	1
GO:0004300	enoyl-CoA hydratase activity	1/571	10/18367	0.270865650747294	0.623883945397626	ECHS1	1
GO:0004523	RNA-DNA hybrid ribonuclease activity	1/571	10/18367	0.270865650747294	0.623883945397626	RNASEH2A	1
GO:0004955	prostaglandin receptor activity	1/571	10/18367	0.270865650747294	0.623883945397626	HPGD	1
GO:0005522	profilin binding	1/571	10/18367	0.270865650747294	0.623883945397626	ACTG1	1
GO:0008239	dipeptidyl-peptidase activity	1/571	10/18367	0.270865650747294	0.623883945397626	DPP4	1
GO:0015924	mannosyl-oligosaccharide mannosidase activity	1/571	10/18367	0.270865650747294	0.623883945397626	EDEM3	1
GO:0016175	superoxide-generating NAD(P)H oxidase activity	1/571	10/18367	0.270865650747294	0.623883945397626	CYBA	1
GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	1/571	10/18367	0.270865650747294	0.623883945397626	GMPS	1
GO:0019531	oxalate transmembrane transporter activity	1/571	10/18367	0.270865650747294	0.623883945397626	SLC26A2	1
GO:0031957	very long-chain fatty acid-CoA ligase activity	1/571	10/18367	0.270865650747294	0.623883945397626	SLC27A2	1
GO:0032356	oxidized DNA binding	1/571	10/18367	0.270865650747294	0.623883945397626	RPS3	1
GO:0034713	type I transforming growth factor beta receptor binding	1/571	10/18367	0.270865650747294	0.623883945397626	ENG	1
GO:0043139	5'-3' DNA helicase activity	1/571	10/18367	0.270865650747294	0.623883945397626	RUVBL1	1
GO:0043208	glycosphingolipid binding	1/571	10/18367	0.270865650747294	0.623883945397626	PSAP	1
GO:0051880	G-quadruplex DNA binding	1/571	10/18367	0.270865650747294	0.623883945397626	NME2	1
GO:0070008	serine-type exopeptidase activity	1/571	10/18367	0.270865650747294	0.623883945397626	CPD	1
GO:0070567	cytidylyltransferase activity	1/571	10/18367	0.270865650747294	0.623883945397626	NANS	1
GO:0099528	G protein-coupled neurotransmitter receptor activity	1/571	10/18367	0.270865650747294	0.623883945397626	ADRB1	1
GO:0008509	anion transmembrane transporter activity	12/571	314/18367	0.27305105535263	0.623883945397626	VDAC2/VDAC1/SLC25A5/SLC2A1/SLC26A2/SLC6A4/SLC19A1/SLC38A2/SLC52A1/GJA1/SLC13A4/SLC1A5	12
GO:0001530	lipopolysaccharide binding	2/571	33/18367	0.273894116827962	0.623883945397626	HMGB1/HSPD1	2
GO:0005154	epidermal growth factor receptor binding	2/571	33/18367	0.273894116827962	0.623883945397626	SNX2/EFEMP1	2
GO:0008200	ion channel inhibitor activity	2/571	33/18367	0.273894116827962	0.623883945397626	CALM1/PHPT1	2
GO:0003823	antigen binding	7/571	171/18367	0.283130775627723	0.623883945397626	HLA-B/HLA-C/HLA-DRB1/HLA-DPA1/HLA-A/HLA-DRA/HLA-DPB1	7
GO:0008376	acetylgalactosaminyltransferase activity	2/571	34/18367	0.285514046327927	0.623883945397626	CHPF/GALNT11	2
GO:0016248	channel inhibitor activity	2/571	34/18367	0.285514046327927	0.623883945397626	CALM1/PHPT1	2
GO:0043548	phosphatidylinositol 3-kinase binding	2/571	34/18367	0.285514046327927	0.623883945397626	CALM1/IGF1R	2
GO:0008194	UDP-glycosyltransferase activity	6/571	143/18367	0.285903731381332	0.623883945397626	CHPF/B4GALT1/GALNT11/HEXB/B3GNT3/HEXA	6
GO:0001786	phosphatidylserine binding	3/571	60/18367	0.286245680088968	0.623883945397626	HMGB1/SCIN/MME	3
GO:0032934	sterol binding	3/571	60/18367	0.286245680088968	0.623883945397626	VDAC2/VDAC1/ABCA1	3
GO:0016651	oxidoreductase activity, acting on NAD(P)H	4/571	88/18367	0.292699710030766	0.623883945397626	CYBA/NDUFB3/NDUFA10/NDUFS3	4
GO:0002162	dystroglycan binding	1/571	11/18367	0.29354559373489	0.623883945397626	DAG1	1
GO:0004596	peptide alpha-N-acetyltransferase activity	1/571	11/18367	0.29354559373489	0.623883945397626	NAA20	1
GO:0004954	prostanoid receptor activity	1/571	11/18367	0.29354559373489	0.623883945397626	HPGD	1
GO:0005049	nuclear export signal receptor activity	1/571	11/18367	0.29354559373489	0.623883945397626	RAN	1
GO:0005078	MAP-kinase scaffold activity	1/571	11/18367	0.29354559373489	0.623883945397626	IQGAP1	1
GO:0005347	ATP transmembrane transporter activity	1/571	11/18367	0.29354559373489	0.623883945397626	SLC25A5	1
GO:0005536	glucose binding	1/571	11/18367	0.29354559373489	0.623883945397626	UGP2	1
GO:0008603	cAMP-dependent protein kinase regulator activity	1/571	11/18367	0.29354559373489	0.623883945397626	PKIB	1
GO:0010485	H4 histone acetyltransferase activity	1/571	11/18367	0.29354559373489	0.623883945397626	HAT1	1
GO:0015378	sodium:chloride symporter activity	1/571	11/18367	0.29354559373489	0.623883945397626	SLC6A4	1
GO:0016832	aldehyde-lyase activity	1/571	11/18367	0.29354559373489	0.623883945397626	ALDOA	1
GO:0019864	IgG binding	1/571	11/18367	0.29354559373489	0.623883945397626	FCER1G	1
GO:0035673	oligopeptide transmembrane transporter activity	1/571	11/18367	0.29354559373489	0.623883945397626	GJA1	1
GO:0043560	insulin receptor substrate binding	1/571	11/18367	0.29354559373489	0.623883945397626	IGF1R	1
GO:0047676	arachidonate-CoA ligase activity	1/571	11/18367	0.29354559373489	0.623883945397626	SLC27A2	1
GO:0048407	platelet-derived growth factor binding	1/571	11/18367	0.29354559373489	0.623883945397626	COL4A1	1
GO:0097371	MDM2/MDM4 family protein binding	1/571	11/18367	0.29354559373489	0.623883945397626	RPS20	1
GO:0099186	structural constituent of postsynapse	1/571	11/18367	0.29354559373489	0.623883945397626	ACTG1	1
GO:1990459	transferrin receptor binding	1/571	11/18367	0.29354559373489	0.623883945397626	SNX2	1
GO:0005507	copper ion binding	3/571	61/18367	0.294774696348946	0.623883945397626	F5/AOC1/PARK7	3
GO:0015179	L-amino acid transmembrane transporter activity	3/571	61/18367	0.294774696348946	0.623883945397626	SLC38A2/SLC43A2/SLC1A5	3
GO:0016247	channel regulator activity	6/571	145/18367	0.296688954813019	0.625283381001473	CALM1/ATP2B4/PHPT1/AKAP9/SRI/PRSS8	6
GO:0042887	amide transmembrane transporter activity	2/571	35/18367	0.297114519294659	0.625283381001473	SLC19A1/GJA1	2
GO:0015248	sterol transporter activity	2/571	36/18367	0.308685529880107	0.635306335730623	APOE/ABCA1	2
GO:0034061	DNA polymerase activity	2/571	36/18367	0.308685529880107	0.635306335730623	PTGES3/POLE3	2
GO:0042805	actinin binding	2/571	36/18367	0.308685529880107	0.635306335730623	CSRP2/DAG1	2
GO:0003906	DNA-(apurinic or apyrimidinic site) endonuclease activity	1/571	12/18367	0.315521267409839	0.635306335730623	RPS3	1
GO:0003964	RNA-directed DNA polymerase activity	1/571	12/18367	0.315521267409839	0.635306335730623	PTGES3	1
GO:0005024	transforming growth factor beta-activated receptor activity	1/571	12/18367	0.315521267409839	0.635306335730623	ENG	1
GO:0005095	GTPase inhibitor activity	1/571	12/18367	0.315521267409839	0.635306335730623	IQGAP1	1
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	1/571	12/18367	0.315521267409839	0.635306335730623	CDK1	1
GO:0017166	vinculin binding	1/571	12/18367	0.315521267409839	0.635306335730623	DAG1	1
GO:0030955	potassium ion binding	1/571	12/18367	0.315521267409839	0.635306335730623	PKM	1
GO:0035256	G protein-coupled glutamate receptor binding	1/571	12/18367	0.315521267409839	0.635306335730623	CALM1	1
GO:0043176	amine binding	1/571	12/18367	0.315521267409839	0.635306335730623	SLC6A4	1
GO:0046790	virion binding	1/571	12/18367	0.315521267409839	0.635306335730623	PPIA	1
GO:0051378	serotonin binding	1/571	12/18367	0.315521267409839	0.635306335730623	SLC6A4	1
GO:0061578	Lys63-specific deubiquitinase activity	1/571	12/18367	0.315521267409839	0.635306335730623	PSMD14	1
GO:0070410	co-SMAD binding	1/571	12/18367	0.315521267409839	0.635306335730623	TGIF1	1
GO:0046915	transition metal ion transmembrane transporter activity	2/571	37/18367	0.32021771102629	0.643024783597267	SLC40A1/SLC39A10	2
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	2/571	38/18367	0.331702304536447	0.656876453997635	PPIA/PPIH	2
GO:0044390	ubiquitin-like protein conjugating enzyme binding	2/571	38/18367	0.331702304536447	0.656876453997635	RPS3/PARK7	2
GO:0140303	intramembrane lipid transporter activity	2/571	38/18367	0.331702304536447	0.656876453997635	ATP10D/ABCA1	2
GO:0004865	protein serine/threonine phosphatase inhibitor activity	1/571	13/18367	0.336814503928989	0.656876453997635	PPP1R14B	1
GO:0008179	adenylate cyclase binding	1/571	13/18367	0.336814503928989	0.656876453997635	CALM1	1
GO:0008195	phosphatidate phosphatase activity	1/571	13/18367	0.336814503928989	0.656876453997635	PLPP3	1
GO:0031432	titin binding	1/571	13/18367	0.336814503928989	0.656876453997635	CALM1	1
GO:0061133	endopeptidase activator activity	1/571	13/18367	0.336814503928989	0.656876453997635	PSMD14	1
GO:0061783	peptidoglycan muralytic activity	1/571	13/18367	0.336814503928989	0.656876453997635	LYZ	1
GO:0072542	protein phosphatase activator activity	1/571	13/18367	0.336814503928989	0.656876453997635	CALM1	1
GO:0140299	small molecule sensor activity	1/571	13/18367	0.336814503928989	0.656876453997635	PARK7	1
GO:0016776	phosphotransferase activity, phosphate group as acceptor	2/571	39/18367	0.343131132384407	0.667448286230765	NME1/NME2	2
GO:0017080	sodium channel regulator activity	2/571	40/18367	0.354496569214343	0.675882265378474	ATP2B4/PRSS8	2
GO:0042287	MHC protein binding	2/571	40/18367	0.354496569214343	0.675882265378474	CD74/TUBB4B	2
GO:0043028	cysteine-type endopeptidase regulator activity involved in apoptotic process	2/571	40/18367	0.354496569214343	0.675882265378474	PRDX3/BIRC5	2
GO:0051536	iron-sulfur cluster binding	3/571	68/18367	0.354660215852	0.675882265378474	RPS3/SDHB/GLRX3	3
GO:0051540	metal cluster binding	3/571	68/18367	0.354660215852	0.675882265378474	RPS3/SDHB/GLRX3	3
GO:0004896	cytokine receptor activity	4/571	97/18367	0.356283850399919	0.675882265378474	CD74/CSF3R/IL6ST/PRLR	4
GO:0004065	arylsulfatase activity	1/571	14/18367	0.357446459810898	0.675882265378474	STS	1
GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity	1/571	14/18367	0.357446459810898	0.675882265378474	B3GNT3	1
GO:0015562	efflux transmembrane transporter activity	1/571	14/18367	0.357446459810898	0.675882265378474	GJA1	1
GO:0017110	nucleoside-diphosphatase activity	1/571	14/18367	0.357446459810898	0.675882265378474	NUDT15	1
GO:0045028	G protein-coupled purinergic nucleotide receptor activity	1/571	14/18367	0.357446459810898	0.675882265378474	P2RY6	1
GO:0042826	histone deacetylase binding	5/571	127/18367	0.360813285028523	0.677440544263485	HSP90AB1/HNRNPD/GMNN/BEX4/CDC20	5
GO:0016859	cis-trans isomerase activity	2/571	41/18367	0.365791515984823	0.677440544263485	PPIA/PPIH	2
GO:0001046	core promoter sequence-specific DNA binding	2/571	42/18367	0.377009374712777	0.677440544263485	NPM1/PIH1D1	2
GO:0004467	long-chain fatty acid-CoA ligase activity	1/571	15/18367	0.377437636809098	0.677440544263485	SLC27A2	1
GO:0004559	alpha-mannosidase activity	1/571	15/18367	0.377437636809098	0.677440544263485	EDEM3	1
GO:0004953	icosanoid receptor activity	1/571	15/18367	0.377437636809098	0.677440544263485	HPGD	1
GO:0005545	1-phosphatidylinositol binding	1/571	15/18367	0.377437636809098	0.677440544263485	SCIN	1
GO:0010851	cyclase regulator activity	1/571	15/18367	0.377437636809098	0.677440544263485	CALM1	1
GO:0030280	structural constituent of skin epidermis	1/571	15/18367	0.377437636809098	0.677440544263485	KRT10	1
GO:0034483	heparan sulfate sulfotransferase activity	1/571	15/18367	0.377437636809098	0.677440544263485	HS6ST2	1
GO:0042809	vitamin D receptor binding	1/571	15/18367	0.377437636809098	0.677440544263485	MED4	1
GO:0042813	Wnt-activated receptor activity	1/571	15/18367	0.377437636809098	0.677440544263485	LRP5	1
GO:0048185	activin binding	1/571	15/18367	0.377437636809098	0.677440544263485	ENG	1
GO:0050664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	1/571	15/18367	0.377437636809098	0.677440544263485	CYBA	1
GO:1904680	peptide transmembrane transporter activity	1/571	15/18367	0.377437636809098	0.677440544263485	GJA1	1
GO:0005496	steroid binding	4/571	100/18367	0.377553454236256	0.677440544263485	VDAC2/VDAC1/ABCA1/PAQR7	4
GO:0005543	phospholipid binding	16/571	466/18367	0.377967200612093	0.677440544263485	PFN1/APOC1/APOE/HMGB1/VDAC2/ANXA1/VDAC1/PSAP/ANXA5/SNX2/ANXA3/STOML2/ABCA1/IQGAP1/SCIN/MME	16
GO:0008237	metallopeptidase activity	7/571	190/18367	0.378370366735734	0.677440544263485	EIF3H/ADAMTS6/PSMD14/CPD/MME/COPS5/TFRC	7
GO:0015078	proton transmembrane transporter activity	5/571	130/18367	0.379387233933015	0.677440544263485	SLC25A5/UQCRH/COX4I1/COX7A2L/COX5A	5
GO:0017124	SH3 domain binding	5/571	130/18367	0.379387233933015	0.677440544263485	LRP2/CYBA/GPX1/PTTG1/GJA1	5
GO:0030544	Hsp70 protein binding	2/571	43/18367	0.38814402427467	0.677440544263485	RPS3/DNAJA1	2
GO:0000049	tRNA binding	3/571	72/18367	0.388657476027179	0.677440544263485	EEF1A1/SSB/EIF2A	3
GO:0016779	nucleotidyltransferase activity	5/571	132/18367	0.391763950483933	0.677440544263485	PTGES3/UGP2/POLE3/POLR2H/NANS	5
GO:0000900	translation repressor activity, mRNA regulatory element binding	1/571	16/18367	0.396807902141596	0.677440544263485	TYMS	1
GO:0003688	DNA replication origin binding	1/571	16/18367	0.396807902141596	0.677440544263485	HSPD1	1
GO:0005092	GDP-dissociation inhibitor activity	1/571	16/18367	0.396807902141596	0.677440544263485	RANBP1	1
GO:0005159	insulin-like growth factor receptor binding	1/571	16/18367	0.396807902141596	0.677440544263485	IGF2	1
GO:0005283	amino acid:sodium symporter activity	1/571	16/18367	0.396807902141596	0.677440544263485	SLC38A2	1
GO:0008191	metalloendopeptidase inhibitor activity	1/571	16/18367	0.396807902141596	0.677440544263485	TIMP3	1
GO:0015172	acidic amino acid transmembrane transporter activity	1/571	16/18367	0.396807902141596	0.677440544263485	SLC1A5	1
GO:0015556	C4-dicarboxylate transmembrane transporter activity	1/571	16/18367	0.396807902141596	0.677440544263485	SLC1A5	1
GO:0015923	mannosidase activity	1/571	16/18367	0.396807902141596	0.677440544263485	EDEM3	1
GO:0016004	phospholipase activator activity	1/571	16/18367	0.396807902141596	0.677440544263485	GM2A	1
GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	1/571	16/18367	0.396807902141596	0.677440544263485	AOC1	1
GO:0036122	BMP binding	1/571	16/18367	0.396807902141596	0.677440544263485	ENG	1
GO:0042577	lipid phosphatase activity	1/571	16/18367	0.396807902141596	0.677440544263485	PLPP3	1
GO:0070403	NAD+ binding	1/571	16/18367	0.396807902141596	0.677440544263485	HPGD	1
GO:0070492	oligosaccharide binding	1/571	16/18367	0.396807902141596	0.677440544263485	LGALS1	1
GO:0140327	flippase activity	1/571	16/18367	0.396807902141596	0.677440544263485	ATP10D	1
GO:0015370	solute:sodium symporter activity	3/571	73/18367	0.39709413851349	0.677440544263485	SLC6A4/SLC38A2/SLC13A4	3
GO:0106306	protein serine phosphatase activity	3/571	73/18367	0.39709413851349	0.677440544263485	PPP1CA/PPM1G/PPP4C	3
GO:0106307	protein threonine phosphatase activity	3/571	73/18367	0.39709413851349	0.677440544263485	PPP1CA/PPM1G/PPP4C	3
GO:0008238	exopeptidase activity	4/571	103/18367	0.398755025874787	0.677440544263485	DPP4/CPD/MME/TFRC	4
GO:0031490	chromatin DNA binding	4/571	103/18367	0.398755025874787	0.677440544263485	HMGN2/HMGN1/HNRNPC/POLE3	4
GO:0051879	Hsp90 protein binding	2/571	44/18367	0.399189797223718	0.677440544263485	RPS3/PTGES3	2
GO:0019902	phosphatase binding	7/571	196/18367	0.4089613003234	0.683453639143135	ATP2B4/EGFR/PPP1CA/MET/HSP90B1/IQGAP1/GTF2F1	7
GO:0019003	GDP binding	3/571	75/18367	0.413869367260231	0.683453639143135	RAN/GNAI3/NME2	3
GO:0004697	protein kinase C activity	1/571	17/18367	0.41557650809643	0.683453639143135	SMG1	1
GO:0005001	transmembrane receptor protein tyrosine phosphatase activity	1/571	17/18367	0.41557650809643	0.683453639143135	PTPRF	1
GO:0008525	phosphatidylcholine transporter activity	1/571	17/18367	0.41557650809643	0.683453639143135	ABCA1	1
GO:0015108	chloride transmembrane transporter activity	1/571	17/18367	0.41557650809643	0.683453639143135	SLC26A2	1
GO:0015377	cation:chloride symporter activity	1/571	17/18367	0.41557650809643	0.683453639143135	SLC6A4	1
GO:0019198	transmembrane receptor protein phosphatase activity	1/571	17/18367	0.41557650809643	0.683453639143135	PTPRF	1
GO:0030169	low-density lipoprotein particle binding	1/571	17/18367	0.41557650809643	0.683453639143135	COLEC12	1
GO:0031420	alkali metal ion binding	1/571	17/18367	0.41557650809643	0.683453639143135	PKM	1
GO:0031489	myosin V binding	1/571	17/18367	0.41557650809643	0.683453639143135	RAB25	1
GO:0048531	beta-1,3-galactosyltransferase activity	1/571	17/18367	0.41557650809643	0.683453639143135	B3GNT3	1
GO:0052745	inositol phosphate phosphatase activity	1/571	17/18367	0.41557650809643	0.683453639143135	IMPA2	1
GO:0070064	proline-rich region binding	1/571	17/18367	0.41557650809643	0.683453639143135	PFN1	1
GO:0140296	general transcription initiation factor binding	2/571	46/18367	0.420994179580156	0.690838466491665	RUVBL1/GTF2F1	2
GO:0019829	ATPase-coupled cation transmembrane transporter activity	2/571	47/18367	0.431743527275459	0.702506027650466	ATP2B4/ATP2B1	2
GO:0004708	MAP kinase kinase activity	1/571	18/18367	0.433762111032502	0.702506027650466	PBK	1
GO:0008409	5'-3' exonuclease activity	1/571	18/18367	0.433762111032502	0.702506027650466	PLD3	1
GO:0050811	GABA receptor binding	1/571	18/18367	0.433762111032502	0.702506027650466	GABARAP	1
GO:0060229	lipase activator activity	1/571	18/18367	0.433762111032502	0.702506027650466	GM2A	1
GO:0098918	structural constituent of synapse	1/571	18/18367	0.433762111032502	0.702506027650466	ACTG1	1
GO:0042626	ATPase-coupled transmembrane transporter activity	4/571	109/18367	0.440729780263137	0.712242269622639	ATP2B4/SLC26A2/ABCA1/ATP2B1	4
GO:0016879	ligase activity, forming carbon-nitrogen bonds	2/571	48/18367	0.442385435067073	0.713370452651449	MTHFS/GMPS	2
GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity	1/571	19/18367	0.451382789794312	0.722953886300385	GALNT11	1
GO:0004675	transmembrane receptor protein serine/threonine kinase activity	1/571	19/18367	0.451382789794312	0.722953886300385	ENG	1
GO:0005326	neurotransmitter transmembrane transporter activity	1/571	19/18367	0.451382789794312	0.722953886300385	SLC6A4	1
GO:0034212	peptide N-acetyltransferase activity	2/571	49/18367	0.452916189020305	0.722953886300385	HAT1/NAA20	2
GO:0140297	DNA-binding transcription factor binding	13/571	394/18367	0.453180489801718	0.722953886300385	PTMA/NPM1/RPS3/HMGB1/DNAJA1/ISL1/PARK7/GMNN/CHCHD2/SRI/MED4/EXOSC9/CALR	13
GO:0019001	guanyl nucleotide binding	13/571	398/18367	0.467729503103449	0.727082848648268	RAN/EEF1A1/HSP90AB1/TUBA1B/TUBB4B/NME1/TUBA1C/RAB25/ARF5/SLC19A1/GNAI3/NME2/RAB38	13
GO:0032561	guanyl ribonucleotide binding	13/571	398/18367	0.467729503103449	0.727082848648268	RAN/EEF1A1/HSP90AB1/TUBA1B/TUBB4B/NME1/TUBA1C/RAB25/ARF5/SLC19A1/GNAI3/NME2/RAB38	13
GO:0008017	microtubule binding	9/571	271/18367	0.467885487965914	0.727082848648268	GAPDH/RPS3/BIRC5/SKA2/GABARAP/MACF1/HAUS8/TUBGCP2/CLIP1	9
GO:0004551	nucleotide diphosphatase activity	1/571	20/18367	0.468456063558616	0.727082848648268	NUDT15	1
GO:0016408	C-acyltransferase activity	1/571	20/18367	0.468456063558616	0.727082848648268	ACAT2	1
GO:0016638	oxidoreductase activity, acting on the CH-NH2 group of donors	1/571	20/18367	0.468456063558616	0.727082848648268	AOC1	1
GO:0030506	ankyrin binding	1/571	20/18367	0.468456063558616	0.727082848648268	CDH1	1
GO:0031418	L-ascorbic acid binding	1/571	20/18367	0.468456063558616	0.727082848648268	P3H1	1
GO:0031681	G-protein beta-subunit binding	1/571	20/18367	0.468456063558616	0.727082848648268	CCT5	1
GO:0031683	G-protein beta/gamma-subunit complex binding	1/571	20/18367	0.468456063558616	0.727082848648268	GNAI3	1
GO:0031690	adrenergic receptor binding	1/571	20/18367	0.468456063558616	0.727082848648268	ADRB1	1
GO:0042288	MHC class I protein binding	1/571	20/18367	0.468456063558616	0.727082848648268	TUBB4B	1
GO:0061608	nuclear import signal receptor activity	1/571	20/18367	0.468456063558616	0.727082848648268	NUTF2	1
GO:0051018	protein kinase A binding	2/571	51/18367	0.473631031567948	0.733586524985698	RPS3/AKAP9	2
GO:0101005	deubiquitinase activity	4/571	114/18367	0.475034673804913	0.734234091254481	EIF3H/PSMD14/UCHL3/COPS5	4
GO:0016830	carbon-carbon lyase activity	2/571	52/18367	0.483809293623787	0.737396300616837	ALDOA/UMPS	2
GO:0031593	polyubiquitin modification-dependent protein binding	2/571	52/18367	0.483809293623787	0.737396300616837	PSMD4/UBXN1	2
GO:0001614	purinergic nucleotide receptor activity	1/571	21/18367	0.484998909130537	0.737396300616837	P2RY6	1
GO:0001848	complement binding	1/571	21/18367	0.484998909130537	0.737396300616837	CALR	1
GO:0005243	gap junction channel activity	1/571	21/18367	0.484998909130537	0.737396300616837	GJA1	1
GO:0005385	zinc ion transmembrane transporter activity	1/571	21/18367	0.484998909130537	0.737396300616837	SLC39A10	1
GO:0016502	nucleotide receptor activity	1/571	21/18367	0.484998909130537	0.737396300616837	P2RY6	1
GO:0051010	microtubule plus-end binding	1/571	21/18367	0.484998909130537	0.737396300616837	CLIP1	1
GO:0019842	vitamin binding	5/571	148/18367	0.489186202714145	0.741593891235051	TYMS/SLC19A1/MTHFS/FOLR1/P3H1	5
GO:0042393	histone binding	8/571	244/18367	0.489750596627711	0.741593891235051	NPM1/CKS1B/DNAJC9/DEK/HAT1/CKS2/VRK1/PIH1D1	8
GO:1901505	carbohydrate derivative transmembrane transporter activity	2/571	53/18367	0.49386471674641	0.74207891529028	SLC25A5/SLC19A1	2
GO:0000062	fatty-acyl-CoA binding	1/571	22/18367	0.501027777706055	0.74207891529028	ACBD6	1
GO:0005355	glucose transmembrane transporter activity	1/571	22/18367	0.501027777706055	0.74207891529028	SLC2A1	1
GO:0005416	amino acid:cation symporter activity	1/571	22/18367	0.501027777706055	0.74207891529028	SLC38A2	1
GO:0005537	mannose binding	1/571	22/18367	0.501027777706055	0.74207891529028	LMAN1	1
GO:0015106	bicarbonate transmembrane transporter activity	1/571	22/18367	0.501027777706055	0.74207891529028	SLC26A2	1
GO:0015149	hexose transmembrane transporter activity	1/571	22/18367	0.501027777706055	0.74207891529028	SLC2A1	1
GO:0015645	fatty acid ligase activity	1/571	22/18367	0.501027777706055	0.74207891529028	SLC27A2	1
GO:0017075	syntaxin-1 binding	1/571	22/18367	0.501027777706055	0.74207891529028	SLC6A4	1
GO:0030021	extracellular matrix structural constituent conferring compression resistance	1/571	22/18367	0.501027777706055	0.74207891529028	PRG2	1
GO:0030742	GTP-dependent protein binding	1/571	22/18367	0.501027777706055	0.74207891529028	RAB38	1
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	2/571	54/18367	0.503795092221541	0.744697110525889	P3H1/P4HB	2
GO:0005506	iron ion binding	5/571	151/18367	0.506889682444045	0.74725468986876	FTL/HBA2/RRM2/P3H1/CALR	5
GO:0004197	cysteine-type endopeptidase activity	4/571	119/18367	0.508513147411758	0.74725468986876	LGMN/CTSD/CTSF/CTSB	4
GO:0015103	inorganic anion transmembrane transporter activity	5/571	152/18367	0.512736823459605	0.74725468986876	VDAC2/VDAC1/SLC26A2/SLC6A4/SLC13A4	5
GO:0004529	exodeoxyribonuclease activity	1/571	23/18367	0.516558611117331	0.74725468986876	PLD3	1
GO:0005212	structural constituent of eye lens	1/571	23/18367	0.516558611117331	0.74725468986876	VIM	1
GO:0008143	poly(A) binding	1/571	23/18367	0.516558611117331	0.74725468986876	EIF4A3	1
GO:0016895	exodeoxyribonuclease activity, producing 5'-phosphomonoesters	1/571	23/18367	0.516558611117331	0.74725468986876	PLD3	1
GO:0017025	TBP-class protein binding	1/571	23/18367	0.516558611117331	0.74725468986876	RUVBL1	1
GO:0019865	immunoglobulin binding	1/571	23/18367	0.516558611117331	0.74725468986876	FCER1G	1
GO:0140103	catalytic activity, acting on a glycoprotein	1/571	23/18367	0.516558611117331	0.74725468986876	B3GNT3	1
GO:1901567	fatty acid derivative binding	1/571	23/18367	0.516558611117331	0.74725468986876	ACBD6	1
GO:0015297	antiporter activity	3/571	89/18367	0.52596306086685	0.755815093310488	SLC25A5/SLC26A2/SLC19A1	3
GO:0043178	alcohol binding	3/571	89/18367	0.52596306086685	0.755815093310488	VDAC2/VDAC1/ABCA1	3
GO:0003707	steroid hormone receptor activity	1/571	24/18367	0.531606857576773	0.755815093310488	PAQR7	1
GO:0015145	monosaccharide transmembrane transporter activity	1/571	24/18367	0.531606857576773	0.755815093310488	SLC2A1	1
GO:0016769	transferase activity, transferring nitrogenous groups	1/571	24/18367	0.531606857576773	0.755815093310488	GAPDH	1
GO:0019789	SUMO transferase activity	1/571	24/18367	0.531606857576773	0.755815093310488	SUMO2	1
GO:0043274	phospholipase binding	1/571	24/18367	0.531606857576773	0.755815093310488	SRSF3	1
GO:0051537	2 iron, 2 sulfur cluster binding	1/571	24/18367	0.531606857576773	0.755815093310488	SDHB	1
GO:0120014	phospholipid transfer activity	1/571	24/18367	0.531606857576773	0.755815093310488	TRIAP1	1
GO:0005548	phospholipid transporter activity	2/571	57/18367	0.532817594836666	0.755899188520037	TRIAP1/ABCA1	2
GO:0000287	magnesium ion binding	7/571	221/18367	0.533695265988644	0.755899188520037	RAN/ENO1/PKM/ATP10D/NME1/DUT/S100P	7
GO:0016407	acetyltransferase activity	3/571	91/18367	0.541013291481695	0.762003141885404	HAT1/ACAT2/NAA20	3
GO:0003887	DNA-directed DNA polymerase activity	1/571	25/18367	0.54618748693531	0.762003141885404	POLE3	1
GO:0005112	Notch binding	1/571	25/18367	0.54618748693531	0.762003141885404	GALNT11	1
GO:0005160	transforming growth factor beta receptor binding	1/571	25/18367	0.54618748693531	0.762003141885404	ENG	1
GO:0008327	methyl-CpG binding	1/571	25/18367	0.54618748693531	0.762003141885404	ERH	1
GO:0034237	protein kinase A regulatory subunit binding	1/571	25/18367	0.54618748693531	0.762003141885404	AKAP9	1
GO:0051019	mitogen-activated protein kinase binding	1/571	25/18367	0.54618748693531	0.762003141885404	IQGAP1	1
GO:0120227	acyl-CoA binding	1/571	25/18367	0.54618748693531	0.762003141885404	ACBD6	1
GO:0019783	ubiquitin-like protein-specific protease activity	4/571	125/18367	0.547364166190417	0.762217390302543	EIF3H/PSMD14/UCHL3/COPS5	4
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	2/571	59/18367	0.551511076660192	0.766559239014632	PLD3/EXOSC9	2
GO:0031267	small GTPase binding	8/571	259/18367	0.557588281732368	0.771598297735701	RANBP1/PFN1/YBX3/NUTF2/BIRC5/ABCA1/IQGAP1/ATP6AP1	8
GO:0008198	ferrous iron binding	1/571	26/18367	0.560315005469818	0.771598297735701	FTL	1
GO:0038187	pattern recognition receptor activity	1/571	26/18367	0.560315005469818	0.771598297735701	COLEC12	1
GO:0043225	ATPase-coupled inorganic anion transmembrane transporter activity	1/571	26/18367	0.560315005469818	0.771598297735701	SLC26A2	1
GO:0097602	cullin family protein binding	1/571	26/18367	0.560315005469818	0.771598297735701	ANAPC11	1
GO:0043621	protein self-association	2/571	61/18367	0.569671158044702	0.776102695661669	SLC2A1/MDH2	2
GO:0001671	ATPase activator activity	1/571	27/18367	0.574003470214201	0.776102695661669	DNAJA1	1
GO:0004190	aspartic-type endopeptidase activity	1/571	27/18367	0.574003470214201	0.776102695661669	CTSD	1
GO:0004709	MAP kinase kinase kinase activity	1/571	27/18367	0.574003470214201	0.776102695661669	EGFR	1
GO:0016405	CoA-ligase activity	1/571	27/18367	0.574003470214201	0.776102695661669	SLC27A2	1
GO:0035255	ionotropic glutamate receptor binding	1/571	27/18367	0.574003470214201	0.776102695661669	CANX	1
GO:0043425	bHLH transcription factor binding	1/571	27/18367	0.574003470214201	0.776102695661669	ISL1	1
GO:0051119	sugar transmembrane transporter activity	1/571	27/18367	0.574003470214201	0.776102695661669	SLC2A1	1
GO:0051393	alpha-actinin binding	1/571	27/18367	0.574003470214201	0.776102695661669	DAG1	1
GO:0051959	dynein light intermediate chain binding	1/571	27/18367	0.574003470214201	0.776102695661669	DYNLL1	1
GO:0030546	signaling receptor activator activity	15/571	495/18367	0.577657599773099	0.778013391976344	FBN1/MIF/SPP1/HMGB2/HMGB1/SEMA6D/SEMA3F/CGA/GRN/EFEMP1/APP/DPP4/GPNMB/IGF2/SEMA6A	15
GO:0016758	hexosyltransferase activity	6/571	197/18367	0.577827937878342	0.778013391976344	CHPF/B4GALT1/GALNT11/HEXB/B3GNT3/HEXA	6
GO:1990841	promoter-specific chromatin binding	2/571	62/18367	0.57854955591261	0.778013391976344	ISL1/GTF2F1	2
GO:0017056	structural constituent of nuclear pore	1/571	28/18367	0.587266502848208	0.785482126789794	NUTF2	1
GO:0051861	glycolipid binding	1/571	28/18367	0.587266502848208	0.785482126789794	PSAP	1
GO:0070001	aspartic-type peptidase activity	1/571	28/18367	0.587266502848208	0.785482126789794	CTSD	1
GO:0004722	protein serine/threonine phosphatase activity	3/571	98/18367	0.591438542168444	0.789644648594069	PPP1CA/PPM1G/PPP4C	3
GO:0004181	metallocarboxypeptidase activity	1/571	29/18367	0.600117303157586	0.794116147162347	CPD	1
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	1/571	29/18367	0.600117303157586	0.794116147162347	CDK1	1
GO:0051059	NF-kappaB binding	1/571	29/18367	0.600117303157586	0.794116147162347	NPM1	1
GO:0051787	misfolded protein binding	1/571	29/18367	0.600117303157586	0.794116147162347	HSPA9	1
GO:0097472	cyclin-dependent protein kinase activity	1/571	29/18367	0.600117303157586	0.794116147162347	CDK1	1
GO:0015085	calcium ion transmembrane transporter activity	4/571	135/18367	0.608344393596512	0.802747789946253	ATP2B4/ITGAV/ATP2B1/SEC61A1	4
GO:0005343	organic acid:sodium symporter activity	1/571	30/18367	0.612568662078789	0.802747789946253	SLC38A2	1
GO:0017147	Wnt-protein binding	1/571	30/18367	0.612568662078789	0.802747789946253	LRP5	1
GO:0046966	thyroid hormone receptor binding	1/571	30/18367	0.612568662078789	0.802747789946253	MED4	1
GO:0002039	p53 binding	2/571	66/18367	0.612712251689773	0.802747789946253	TRIAP1/HSPD1	2
GO:0016887	ATP hydrolysis activity	8/571	272/18367	0.613105359032776	0.802747789946253	ATP2B4/ATP10D/EIF4A3/HSPA9/HSPD1/DDX24/RUVBL1/ATP2B1	8
GO:0015291	secondary active transmembrane transporter activity	7/571	240/18367	0.621022983621882	0.811687934733864	SLC25A5/SLC26A2/SLC6A4/SLC19A1/SLC38A2/SLC13A4/SLC1A5	7
GO:0008157	protein phosphatase 1 binding	1/571	31/18367	0.624632974341046	0.81355168860853	PPP1CA	1
GO:0016878	acid-thiol ligase activity	1/571	31/18367	0.624632974341046	0.81355168860853	SLC27A2	1
GO:0005525	GTP binding	11/571	377/18367	0.627716806787144	0.814536214407302	RAN/EEF1A1/HSP90AB1/TUBA1B/TUBB4B/NME1/TUBA1C/RAB25/ARF5/GNAI3/RAB38	11
GO:0008080	N-acetyltransferase activity	2/571	68/18367	0.628983549403183	0.814536214407302	HAT1/NAA20	2
GO:0020037	heme binding	4/571	139/18367	0.631280008874936	0.814536214407302	CYBA/CYCS/HBA2/HBB	4
GO:0015294	solute:cation symporter activity	3/571	104/18367	0.631709132874096	0.814536214407302	SLC6A4/SLC38A2/SLC13A4	3
GO:0004721	phosphoprotein phosphatase activity	5/571	174/18367	0.632808308718699	0.814536214407302	PTPRF/PHPT1/PPP1CA/PPM1G/PPP4C	5
GO:0001223	transcription coactivator binding	1/571	32/18367	0.636322250718187	0.814536214407302	RPL23	1
GO:0030332	cyclin binding	1/571	32/18367	0.636322250718187	0.814536214407302	CDK1	1
GO:0030515	snoRNA binding	1/571	32/18367	0.636322250718187	0.814536214407302	NHP2	1
GO:0071889	14-3-3 protein binding	1/571	32/18367	0.636322250718187	0.814536214407302	YWHAQ	1
GO:0140658	ATP-dependent chromatin remodeler activity	1/571	32/18367	0.636322250718187	0.814536214407302	SMARCA1	1
GO:0070851	growth factor receptor binding	4/571	141/18367	0.64241936676792	0.819650192256196	IL6ST/SNX2/EFEMP1/APP	4
GO:0001098	basal transcription machinery binding	2/571	70/18367	0.644718137801518	0.819650192256196	RUVBL1/GTF2F1	2
GO:0001099	basal RNA polymerase II transcription machinery binding	2/571	70/18367	0.644718137801518	0.819650192256196	RUVBL1/GTF2F1	2
GO:0004860	protein kinase inhibitor activity	2/571	70/18367	0.644718137801518	0.819650192256196	NPM1/PKIB	2
GO:0031369	translation initiation factor binding	1/571	33/18367	0.647648129902257	0.821972498768623	EIF2S2	1
GO:0019208	phosphatase regulator activity	3/571	107/18367	0.650785057740574	0.823387743848832	CALM1/PPP1R14B/GTF2F1	3
GO:0048018	receptor ligand activity	14/571	487/18367	0.655922553810882	0.823387743848832	FBN1/MIF/SPP1/HMGB2/HMGB1/SEMA6D/SEMA3F/CGA/GRN/EFEMP1/DPP4/GPNMB/IGF2/SEMA6A	14
GO:0015020	glucuronosyltransferase activity	1/571	34/18367	0.65862189001057	0.823387743848832	CHPF	1
GO:0016831	carboxy-lyase activity	1/571	34/18367	0.65862189001057	0.823387743848832	UMPS	1
GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters	1/571	34/18367	0.65862189001057	0.823387743848832	RNASEH2A	1
GO:0030291	protein serine/threonine kinase inhibitor activity	1/571	34/18367	0.65862189001057	0.823387743848832	PKIB	1
GO:0045505	dynein intermediate chain binding	1/571	34/18367	0.65862189001057	0.823387743848832	DYNLL1	1
GO:0015293	symporter activity	4/571	144/18367	0.658710195079066	0.823387743848832	SLC6A4/SLC38A2/SLC13A4/SLC1A5	4
GO:0016922	nuclear receptor binding	4/571	144/18367	0.658710195079066	0.823387743848832	ISL1/PARK7/MED4/CALR	4
GO:0008235	metalloexopeptidase activity	2/571	72/18367	0.659920639800555	0.823519056367526	CPD/TFRC	2
GO:0000175	3'-5'-exoribonuclease activity	1/571	35/18367	0.669254459737508	0.833770188134521	EXOSC9	1
GO:0019210	kinase inhibitor activity	2/571	74/18367	0.674597121928861	0.836863869200152	NPM1/PKIB	2
GO:0019905	syntaxin binding	2/571	74/18367	0.674597121928861	0.836863869200152	SLC6A4/ABCA1	2
GO:0004222	metalloendopeptidase activity	3/571	111/18367	0.675107631395022	0.836863869200152	ADAMTS6/MME/COPS5	3
GO:0046906	tetrapyrrole binding	4/571	149/18367	0.684731180504472	0.843523571206719	CYBA/CYCS/HBA2/HBB	4
GO:0004843	thiol-dependent deubiquitinase	3/571	113/18367	0.686791875186953	0.843523571206719	PSMD14/UCHL3/COPS5	3
GO:0004175	endopeptidase activity	12/571	430/18367	0.689349099292281	0.843523571206719	ADAMTS6/LGMN/PSMA4/PSMB1/DPP4/CTSD/MME/PRSS8/CTSF/COPS5/HTRA1/CTSB	12
GO:0005109	frizzled binding	1/571	37/18367	0.689538060221331	0.843523571206719	ZNRF3	1
GO:0016620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	1/571	37/18367	0.689538060221331	0.843523571206719	GAPDH	1
GO:0030551	cyclic nucleotide binding	1/571	37/18367	0.689538060221331	0.843523571206719	SLC19A1	1
GO:0043531	ADP binding	1/571	37/18367	0.689538060221331	0.843523571206719	RUVBL1	1
GO:0071949	FAD binding	1/571	37/18367	0.689538060221331	0.843523571206719	QSOX1	1
GO:0003724	RNA helicase activity	2/571	77/18367	0.695641861508447	0.848389130556661	EIF4A3/DDX24	2
GO:0004520	endodeoxyribonuclease activity	1/571	38/18367	0.699209296861463	0.848389130556661	RPS3	1
GO:0016251	RNA polymerase II general transcription initiation factor activity	1/571	38/18367	0.699209296861463	0.848389130556661	GTF2F1	1
GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters	1/571	38/18367	0.699209296861463	0.848389130556661	EXOSC9	1
GO:0019213	deacetylase activity	1/571	38/18367	0.699209296861463	0.848389130556661	ESD	1
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	1/571	39/18367	0.708579774874017	0.854745988747587	POLR2H	1
GO:0004402	histone acetyltransferase activity	1/571	39/18367	0.708579774874017	0.854745988747587	HAT1	1
GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	1/571	39/18367	0.708579774874017	0.854745988747587	IQGAP1	1
GO:0008186	ATP-dependent activity, acting on RNA	2/571	79/18367	0.709037612142293	0.854745988747587	EIF4A3/DDX24	2
GO:0004527	exonuclease activity	2/571	80/18367	0.715548832177223	0.856820239446952	PLD3/EXOSC9	2
GO:0004177	aminopeptidase activity	1/571	40/18367	0.717658831429393	0.856820239446952	DPP4	1
GO:0004532	exoribonuclease activity	1/571	40/18367	0.717658831429393	0.856820239446952	EXOSC9	1
GO:0015144	carbohydrate transmembrane transporter activity	1/571	40/18367	0.717658831429393	0.856820239446952	SLC2A1	1
GO:0042169	SH2 domain binding	1/571	40/18367	0.717658831429393	0.856820239446952	DAG1	1
GO:0043014	alpha-tubulin binding	1/571	40/18367	0.717658831429393	0.856820239446952	BEX4	1
GO:0003924	GTPase activity	9/571	337/18367	0.724532119682749	0.861798341027155	RAN/EEF1A1/TUBA1B/TUBB4B/TUBA1C/RAB25/ARF5/GNAI3/RAB38	9
GO:0016877	ligase activity, forming carbon-sulfur bonds	1/571	41/18367	0.726455514315508	0.861798341027155	SLC27A2	1
GO:0030331	estrogen receptor binding	1/571	41/18367	0.726455514315508	0.861798341027155	ISL1	1
GO:0061733	peptide-lysine-N-acetyltransferase activity	1/571	41/18367	0.726455514315508	0.861798341027155	HAT1	1
GO:0005546	phosphatidylinositol-4,5-bisphosphate binding	2/571	82/18367	0.72820437374515	0.862499615962061	PFN1/SCIN	2
GO:0019894	kinesin binding	1/571	42/18367	0.734978590891184	0.866977730792114	CLSTN1	1
GO:0051539	4 iron, 4 sulfur cluster binding	1/571	42/18367	0.734978590891184	0.866977730792114	SDHB	1
GO:0005179	hormone activity	3/571	122/18367	0.735476410551162	0.866977730792114	FBN1/CGA/IGF2	3
GO:0016757	glycosyltransferase activity	7/571	270/18367	0.738429503607397	0.86908369697869	CHPF/UMPS/B4GALT1/GALNT11/HEXB/B3GNT3/HEXA	7
GO:0004180	carboxypeptidase activity	1/571	43/18367	0.743236556763006	0.869248406261287	CPD	1
GO:0016790	thiolester hydrolase activity	1/571	43/18367	0.743236556763006	0.869248406261287	ESD	1
GO:0034062	5'-3' RNA polymerase activity	1/571	43/18367	0.743236556763006	0.869248406261287	POLR2H	1
GO:0097747	RNA polymerase activity	1/571	43/18367	0.743236556763006	0.869248406261287	POLR2H	1
GO:0008013	beta-catenin binding	2/571	85/18367	0.746290815426213	0.871259512386511	CDH1/GJA1	2
GO:0001784	phosphotyrosine residue binding	1/571	44/18367	0.751237644194152	0.871259512386511	PFN1	1
GO:0004712	protein serine/threonine/tyrosine kinase activity	1/571	44/18367	0.751237644194152	0.871259512386511	PBK	1
GO:0016903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	1/571	44/18367	0.751237644194152	0.871259512386511	GAPDH	1
GO:0005516	calmodulin binding	5/571	201/18367	0.752729273722247	0.871259512386511	ATP2B4/EGFR/MARCKS/IQGAP1/ATP2B1	5
GO:0008242	omega peptidase activity	3/571	126/18367	0.755111648231433	0.871259512386511	PSMD14/UCHL3/COPS5	3
GO:0016791	phosphatase activity	7/571	275/18367	0.755276791023595	0.871259512386511	PTPRF/PHPT1/PPP1CA/PPM1G/IMPA2/PPP4C/PLPP3	7
GO:0003712	transcription coregulator activity	13/571	489/18367	0.756257557204212	0.871259512386511	NPM1/HMGB2/HMGB1/PA2G4/UBE2L3/SUB1/PARK7/VGLL1/GMNN/RUVBL1/MED4/NME2/COPS5	13
GO:0005253	anion channel activity	2/571	87/18367	0.757767099602106	0.871259512386511	VDAC2/VDAC1	2
GO:0005245	voltage-gated calcium channel activity	1/571	45/18367	0.758989830253484	0.871259512386511	ITGAV	1
GO:0016893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	1/571	45/18367	0.758989830253484	0.871259512386511	RNASEH2A	1
GO:0140223	general transcription initiation factor activity	1/571	45/18367	0.758989830253484	0.871259512386511	GTF2F1	1
GO:0051219	phosphoprotein binding	2/571	88/18367	0.763335250958143	0.874899633790487	PFN1/PIH1D1	2
GO:0004864	protein phosphatase inhibitor activity	1/571	46/18367	0.766500844712891	0.877178386038562	PPP1R14B	1
GO:0019888	protein phosphatase regulator activity	2/571	89/18367	0.768792082914265	0.878451076336085	CALM1/PPP1R14B	2
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	1/571	47/18367	0.773778177700662	0.882794398754966	ADRB1	1
GO:0051213	dioxygenase activity	2/571	92/18367	0.7845099800059	0.893161569775399	P3H1/P4HB	2
GO:0004518	nuclease activity	5/571	210/18367	0.78550717202055	0.893161569775399	RPS3/NME1/RNASEH2A/PLD3/EXOSC9	5
GO:0016763	pentosyltransferase activity	1/571	49/18367	0.787660605828774	0.893161569775399	UMPS	1
GO:0019212	phosphatase inhibitor activity	1/571	49/18367	0.787660605828774	0.893161569775399	PPP1R14B	1
GO:0005048	signal sequence binding	1/571	50/18367	0.794279548621207	0.895420402649981	SEC61A1	1
GO:0016799	hydrolase activity, hydrolyzing N-glycosyl compounds	1/571	50/18367	0.794279548621207	0.895420402649981	DNPH1	1
GO:0140359	ABC-type transporter activity	1/571	50/18367	0.794279548621207	0.895420402649981	ABCA1	1
GO:0016410	N-acyltransferase activity	2/571	94/18367	0.79446024986797	0.895420402649981	HAT1/NAA20	2
GO:0008227	G protein-coupled amine receptor activity	1/571	51/18367	0.800692518962272	0.901081460161469	ADRB1	1
GO:0008146	sulfotransferase activity	1/571	52/18367	0.806905915537536	0.906704233899645	HS6ST2	1
GO:0050661	NADP binding	1/571	53/18367	0.812925938591212	0.910721540226245	GAPDH	1
GO:1901618	organic hydroxy compound transmembrane transporter activity	1/571	53/18367	0.812925938591212	0.910721540226245	SLC6A4	1
GO:0008408	3'-5' exonuclease activity	1/571	54/18367	0.818758596069885	0.914505478368912	EXOSC9	1
GO:0015459	potassium channel regulator activity	1/571	54/18367	0.818758596069885	0.914505478368912	AKAP9	1
GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	7/571	299/18367	0.825294444416966	0.920425690255449	NPM1/DNAJA1/ISL1/PARK7/MED4/EXOSC9/CALR	7
GO:0030374	nuclear receptor coactivator activity	1/571	56/18367	0.829884920139483	0.922782485826739	MED4	1
GO:0045309	protein phosphorylated amino acid binding	1/571	56/18367	0.829884920139483	0.922782485826739	PFN1	1
GO:0008028	monocarboxylic acid transmembrane transporter activity	1/571	58/18367	0.840329327057216	0.933003500234912	SLC27A2	1
GO:0036002	pre-mRNA binding	1/571	59/18367	0.845308952064061	0.936907527544494	HNRNPA1	1
GO:0019787	ubiquitin-like protein transferase activity	11/571	458/18367	0.846989219097973	0.936907527544494	UBE2L3/UBE2N/UBE2T/UBE2D2/SUMO2/AMFR/UBE2S/ANAPC11/CCNB1IP1/NHLRC3/ZNRF3	11
GO:0008236	serine-type peptidase activity	4/571	191/18367	0.848806905781049	0.936907527544494	DPP4/CPD/PRSS8/HTRA1	4
GO:1902936	phosphatidylinositol bisphosphate binding	2/571	107/18367	0.849750312455314	0.936907527544494	PFN1/SCIN	2
GO:0016627	oxidoreductase activity, acting on the CH-CH group of donors	1/571	60/18367	0.850133541771917	0.936907527544494	SDHB	1
GO:0015081	sodium ion transmembrane transporter activity	3/571	152/18367	0.855573085370434	0.941509525259931	SLC6A4/SLC38A2/SLC13A4	3
GO:0098960	postsynaptic neurotransmitter receptor activity	1/571	62/18367	0.859336740390126	0.942668003166982	ADRB1	1
GO:0017171	serine hydrolase activity	4/571	195/18367	0.859813006261397	0.942668003166982	DPP4/CPD/PRSS8/HTRA1	4
GO:0000149	SNARE binding	2/571	110/18367	0.860421801548386	0.942668003166982	SLC6A4/ABCA1	2
GO:0004842	ubiquitin-protein transferase activity	10/571	433/18367	0.869526933104206	0.951244589078757	UBE2L3/UBE2N/UBE2T/UBE2D2/AMFR/UBE2S/ANAPC11/CCNB1IP1/NHLRC3/ZNRF3	10
GO:0030145	manganese ion binding	1/571	65/18367	0.872094476973243	0.952654523966373	B4GALT1	1
GO:0140030	modification-dependent protein binding	3/571	160/18367	0.878231442161508	0.957953769268409	PSMD4/HSPD1/UBXN1	3
GO:0004540	ribonuclease activity	2/571	116/18367	0.879711280151957	0.958165063908198	RNASEH2A/EXOSC9	2
GO:0008083	growth factor activity	3/571	162/18367	0.883379453127237	0.959700058621165	GRN/EFEMP1/IGF2	3
GO:0016782	transferase activity, transferring sulphur-containing groups	1/571	68/18367	0.883696966730361	0.959700058621165	HS6ST2	1
GO:0042578	phosphoric ester hydrolase activity	8/571	366/18367	0.885880299293453	0.960612326971256	PTPRF/PHPT1/PPP1CA/PPM1G/IMPA2/PPP4C/PLPP3/PLD3	8
GO:0004521	endoribonuclease activity	1/571	69/18367	0.887326073894521	0.960612326971256	RNASEH2A	1
GO:0005262	calcium channel activity	2/571	119/18367	0.888405225883483	0.960612326971256	ITGAV/SEC61A1	2
GO:0016874	ligase activity	3/571	165/18367	0.890738300007104	0.961739178993178	MTHFS/GMPS/SLC27A2	3
GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	1/571	71/18367	0.894248653496795	0.964132050441552	ASAH1	1
GO:0030276	clathrin binding	1/571	72/18367	0.897549048055897	0.966291966476364	LRP1	1
GO:0001664	G protein-coupled receptor binding	6/571	295/18367	0.89984230976126	0.967362944837141	CALM1/DNAJA1/ITGB4/GNAI3/ADRB1/ZNRF3	6
GO:0008168	methyltransferase activity	4/571	214/18367	0.903193158052435	0.968869341640894	TYMS/TRMT112/GCSH/METTL7A	4
GO:0017022	myosin binding	1/571	74/18367	0.903844553611304	0.968869341640894	RAB25	1
GO:1901981	phosphatidylinositol phosphate binding	3/571	173/18367	0.908369453013618	0.972320750711416	PFN1/IQGAP1/SCIN	3
GO:0004252	serine-type endopeptidase activity	3/571	174/18367	0.910382285272929	0.973077191575799	DPP4/PRSS8/HTRA1	3
GO:0004519	endonuclease activity	2/571	129/18367	0.913348447268796	0.974141320540315	RPS3/RNASEH2A	2
GO:0061630	ubiquitin protein ligase activity	6/571	304/18367	0.914300639843744	0.974141320540315	UBE2D2/AMFR/ANAPC11/CCNB1IP1/NHLRC3/ZNRF3	6
GO:0001221	transcription coregulator binding	1/571	78/18367	0.915300569635195	0.974141320540315	RPL23	1
GO:0046332	SMAD binding	1/571	79/18367	0.91794496652613	0.975562054296671	TGIF1	1
GO:0046873	metal ion transmembrane transporter activity	9/571	430/18367	0.921686106115435	0.976742687726974	ATP2B4/SLC6A4/ITGAV/SLC38A2/SLC40A1/SLC39A10/ATP2B1/SLC13A4/SEC61A1	9
GO:0016741	transferase activity, transferring one-carbon groups	4/571	225/18367	0.922481652844462	0.976742687726974	TYMS/TRMT112/GCSH/METTL7A	4
GO:0035591	signaling adaptor activity	1/571	81/18367	0.922989063301731	0.976742687726974	IQGAP1	1
GO:0061659	ubiquitin-like protein ligase activity	6/571	316/18367	0.930737706256148	0.983545519377065	UBE2D2/AMFR/ANAPC11/CCNB1IP1/NHLRC3/ZNRF3	6
GO:0050660	flavin adenine dinucleotide binding	1/571	85/18367	0.932167538497277	0.983661212720214	QSOX1	1
GO:0005125	cytokine activity	4/571	235/18367	0.936948012204293	0.987307311304383	MIF/SPP1/HMGB1/GRN	4
GO:0008276	protein methyltransferase activity	1/571	88/18367	0.938327235740509	0.987364111054632	TRMT112	1
GO:0008081	phosphoric diester hydrolase activity	1/571	89/18367	0.94025377156808	0.987995853058137	PLD3	1
GO:0005244	voltage-gated ion channel activity	3/571	201/18367	0.951595537538768	0.997100809376065	VDAC2/VDAC1/ITGAV	3
GO:0022832	voltage-gated channel activity	3/571	201/18367	0.951595537538768	0.997100809376065	VDAC2/VDAC1/ITGAV	3
GO:0004674	protein serine/threonine kinase activity	7/571	386/18367	0.958109960695327	0.999999537055745	EGFR/CDK1/ENG/PBK/VRK1/NME2/SMG1	7
GO:0004725	protein tyrosine phosphatase activity	1/571	102/18367	0.960457621493057	0.999999537055745	PTPRF	1
GO:0004620	phospholipase activity	1/571	104/18367	0.962891387664362	0.999999537055745	PLD3	1
GO:1990782	protein tyrosine kinase binding	1/571	105/18367	0.964051603272074	0.999999537055745	ITGB1	1
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	5/571	310/18367	0.966214367629795	0.999999537055745	ENO1/PEG3/NFE2L3/TGIF1/ZFHX3	5
GO:0001217	DNA-binding transcription repressor activity	5/571	313/18367	0.968232686064605	0.999999537055745	ENO1/PEG3/NFE2L3/TGIF1/ZFHX3	5
GO:0030594	neurotransmitter receptor activity	1/571	111/18367	0.970290709913954	0.999999537055745	ADRB1	1
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	2/571	170/18367	0.970439235510131	0.999999537055745	P3H1/P4HB	2
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups	3/571	222/18367	0.97058547877669	0.999999537055745	HAT1/ACAT2/NAA20	3
GO:0005126	cytokine receptor binding	4/571	271/18367	0.970963401457458	0.999999537055745	MIF/IL6ST/ENG/PRLR	4
GO:0035091	phosphatidylinositol binding	4/571	271/18367	0.970963401457458	0.999999537055745	PFN1/SNX2/IQGAP1/SCIN	4
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	1/571	125/18367	0.980962300714332	0.999999537055745	ASAH1	1
GO:0003714	transcription corepressor activity	2/571	187/18367	0.981341791882495	0.999999537055745	PA2G4/GMNN	2
GO:0016298	lipase activity	1/571	129/18367	0.983236505812576	0.999999537055745	PLD3	1
GO:0016746	acyltransferase activity	3/571	250/18367	0.985181011243638	0.999999537055745	HAT1/ACAT2/NAA20	3
GO:0022843	voltage-gated cation channel activity	1/571	143/18367	0.989262755458337	0.999999537055745	ITGAV	1
GO:0060090	molecular adaptor activity	5/571	369/18367	0.990428608606346	0.999999537055745	COL14A1/PSMG1/AMFR/AKAP9/IQGAP1	5
GO:0008528	G protein-coupled peptide receptor activity	1/571	147/18367	0.990546612143229	0.999999537055745	LGR5	1
GO:0052689	carboxylic ester hydrolase activity	1/571	147/18367	0.990546612143229	0.999999537055745	ESD	1
GO:0001653	peptide receptor activity	1/571	153/18367	0.992190804605255	0.999999537055745	LGR5	1
GO:0005085	guanyl-nucleotide exchange factor activity	2/571	223/18367	0.993103103596749	0.999999537055745	EEF1B2/ADRB1	2
GO:0140098	catalytic activity, acting on RNA	5/571	386/18367	0.993460124511715	0.999999537055745	EIF4A3/RNASEH2A/POLR2H/DDX24/EXOSC9	5
GO:0030674	protein-macromolecule adaptor activity	3/571	296/18367	0.995398728508482	0.999999537055745	COL14A1/AMFR/IQGAP1	3
GO:0106310	protein serine kinase activity	4/571	360/18367	0.996383730291496	0.999999537055745	CDK1/PBK/VRK1/SMG1	4
GO:0005096	GTPase activator activity	6/571	462/18367	0.996406025748806	0.999999537055745	RANBP1/EEF1B2/PLXNB1/NRP1/IQGAP1/ADRB1	6
GO:0030695	GTPase regulator activity	6/571	488/18367	0.997993158853104	0.999999537055745	RANBP1/EEF1B2/PLXNB1/NRP1/IQGAP1/ADRB1	6
GO:0060589	nucleoside-triphosphatase regulator activity	6/571	488/18367	0.997993158853104	0.999999537055745	RANBP1/EEF1B2/PLXNB1/NRP1/IQGAP1/ADRB1	6
GO:0022836	gated channel activity	3/571	340/18367	0.998555858833554	0.999999537055745	VDAC2/VDAC1/ITGAV	3
GO:0015267	channel activity	5/571	480/18367	0.999287963255822	0.999999537055745	VDAC2/VDAC1/ITGAV/GJA1/SEC61A1	5
GO:0022803	passive transmembrane transporter activity	5/571	481/18367	0.999305177904386	0.999999537055745	VDAC2/VDAC1/ITGAV/GJA1/SEC61A1	5
GO:0005216	ion channel activity	4/571	432/18367	0.999408414686399	0.999999537055745	VDAC2/VDAC1/ITGAV/SEC61A1	4
GO:0005261	cation channel activity	2/571	335/18367	0.999724736816097	0.999999537055745	ITGAV/SEC61A1	2
GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	1/571	450/18367	0.999999437741047	0.999999537055745	ISL1	1
GO:0001216	DNA-binding transcription activator activity	1/571	456/18367	0.999999537055745	0.999999537055745	ISL1	1