ID Description GeneRatio BgRatio pvalue p.adjust geneID Count GO:0002181 cytoplasmic translation 58/566 148/18722 2.47726920919788e-49 1.1028802519349e-45 RPL23A/RPS10/RPS3A/RPL17/RPS6/RPL15/RPL7/RPL36A/RPS8/RPS16/RPL6/RPS3/RPL7A/RPL26/RPL14/RPL5/RPL23/RPS4X/RPS17/RPL27A/RPL3/RPS2/RPL9/RPL13A/RPS11/RPS20/RPL31/RPLP0/RPS18/EIF3E/YBX3/RPSA/RPS13/RPL10A/RPL24/PKM/EIF3H/RPL11/RPL41/RPL21/RPL13/ZC3H15/RPL27/RPS27A/RPS19/RPL19/RPL10/RPL8/RPS25/RPS5/RPS15A/RPL18A/RPL38/RPL29/RPL4/EIF2S2/EIF3I/RPS9 58 GO:0022613 ribonucleoprotein complex biogenesis 57/566 463/18722 1.23460515053793e-19 2.74823106509742e-16 RPL23A/NPM1/RPS6/RPL7/RPS8/RPS16/RPL6/RPL7A/RPL26/RPL14/RPL5/RPS17/RPL3/RPL13A/SNRPD1/SNRPF/RPLP0/RAN/EIF3E/HSP90AB1/PA2G4/RPSA/LSM6/RPL10A/RPL24/SNRPE/EIF3H/RPL11/SRSF9/PTGES3/RPL27/LSM4/RPS19/SNRPD2/EBNA1BP2/EIF4A3/TRMT112/RPL10/RPS25/NHP2/RPS5/SNRPB/NIFK/RPL38/SNRPD3/MRPS7/EIF2S2/EIF3I/SNRPG/RSL1D1/FRG1/RUVBL1/PIH1D1/MALSU1/EIF2A/RPL7L1/EXOSC9 57 GO:0042273 ribosomal large subunit biogenesis 21/566 72/18722 1.56604598231962e-15 2.32401223776231e-12 RPL23A/NPM1/RPL7/RPL6/RPL7A/RPL26/RPL14/RPL5/RPL3/RPLP0/RPL10A/RPL24/RPL11/EBNA1BP2/RPL10/NHP2/NIFK/RPL38/RSL1D1/MALSU1/RPL7L1 21 GO:0042254 ribosome biogenesis 40/566 299/18722 2.54645194791612e-15 2.83420101803064e-12 RPL23A/NPM1/RPS6/RPL7/RPS8/RPS16/RPL6/RPL7A/RPL26/RPL14/RPL5/RPS17/RPL3/RPLP0/RAN/PA2G4/RPSA/LSM6/RPL10A/RPL24/RPL11/RPL27/RPS19/EBNA1BP2/EIF4A3/TRMT112/RPL10/RPS25/NHP2/RPS5/NIFK/RPL38/MRPS7/RSL1D1/FRG1/PIH1D1/MALSU1/EIF2A/RPL7L1/EXOSC9 40 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 38/566 320/18722 5.90508408775226e-13 4.38157239311217e-10 NPM1/HNRNPF/SRSF3/SNRPD1/HNRNPA1/SNRPF/LSM6/LSM3/SNRPE/ZCRB1/SRSF7/NCL/HNRNPM/HNRNPC/SRSF9/ALYREF/MAGOH/LSM4/SNRPD2/RBM8A/SNRNP40/EIF4A3/HNRNPA3/SNRPB/LSM5/SF3B6/LSM8/CIRBP/RBM17/SNRPD3/HNRNPA2B1/PPIH/SNRPG/FRG1/MAGOHB/DAZAP1/RBM23/RBM6 38 GO:0000398 mRNA splicing, via spliceosome 38/566 320/18722 5.90508408775226e-13 4.38157239311217e-10 NPM1/HNRNPF/SRSF3/SNRPD1/HNRNPA1/SNRPF/LSM6/LSM3/SNRPE/ZCRB1/SRSF7/NCL/HNRNPM/HNRNPC/SRSF9/ALYREF/MAGOH/LSM4/SNRPD2/RBM8A/SNRNP40/EIF4A3/HNRNPA3/SNRPB/LSM5/SF3B6/LSM8/CIRBP/RBM17/SNRPD3/HNRNPA2B1/PPIH/SNRPG/FRG1/MAGOHB/DAZAP1/RBM23/RBM6 38 GO:0000375 RNA splicing, via transesterification reactions 38/566 324/18722 8.71188311825595e-13 5.14132061606994e-10 NPM1/HNRNPF/SRSF3/SNRPD1/HNRNPA1/SNRPF/LSM6/LSM3/SNRPE/ZCRB1/SRSF7/NCL/HNRNPM/HNRNPC/SRSF9/ALYREF/MAGOH/LSM4/SNRPD2/RBM8A/SNRNP40/EIF4A3/HNRNPA3/SNRPB/LSM5/SF3B6/LSM8/CIRBP/RBM17/SNRPD3/HNRNPA2B1/PPIH/SNRPG/FRG1/MAGOHB/DAZAP1/RBM23/RBM6 38 GO:0022618 ribonucleoprotein complex assembly 31/566 220/18722 9.23867136760097e-13 5.14132061606994e-10 RPL23A/RPL6/RPL5/RPL3/RPL13A/SNRPD1/SNRPF/RPLP0/EIF3E/HSP90AB1/RPSA/RPL24/SNRPE/EIF3H/RPL11/SRSF9/PTGES3/LSM4/RPS19/SNRPD2/RPL10/RPS5/SNRPB/RPL38/SNRPD3/MRPS7/EIF2S2/EIF3I/SNRPG/RUVBL1/PIH1D1 31 GO:0006457 protein folding 30/566 212/18722 1.93602482256297e-12 8.77532671763443e-10 CD74/HSP90AB1/QSOX1/DNAJA1/PPIA/CCT8/CCT5/CCT6A/PTGES3/NUDC/B2M/CCT7/CCT3/HSPA9/TCP1/CCT2/HSPD1/BAG2/PPIH/GRN/HSPE1/PDCD5/LMAN1/HSP90B1/PFDN4/CANX/MOGS/P3H1/P4HB/CALR 30 GO:0071826 ribonucleoprotein complex subunit organization 31/566 227/18722 2.15125445008294e-12 8.77532671763443e-10 RPL23A/RPL6/RPL5/RPL3/RPL13A/SNRPD1/SNRPF/RPLP0/EIF3E/HSP90AB1/RPSA/RPL24/SNRPE/EIF3H/RPL11/SRSF9/PTGES3/LSM4/RPS19/SNRPD2/RPL10/RPS5/SNRPB/RPL38/SNRPD3/MRPS7/EIF2S2/EIF3I/SNRPG/RUVBL1/PIH1D1 31 GO:0008380 RNA splicing 44/566 434/18722 2.16820741001749e-12 8.77532671763443e-10 NPM1/HNRNPF/SRSF3/YBX1/SNRPD1/HNRNPA1/SNRPF/RPS13/LSM6/LSM3/SNRPE/ZCRB1/SRSF7/NCL/HNRNPM/HNRNPC/SRSF9/ALYREF/MAGOH/LSM4/SNRPD2/RBM8A/SNRNP40/EIF4A3/AHNAK/HNRNPA3/SNRPB/LSM5/SF3B6/LSM8/CIRBP/RBM17/SLC38A2/SNRPD3/HNRNPA2B1/PPIH/SNRPG/THOC6/CTNNBL1/FRG1/MAGOHB/DAZAP1/RBM23/RBM6 44 GO:0006403 RNA localization 28/566 201/18722 1.56951909921199e-11 5.82291585807648e-09 NPM1/SRSF3/YBX1/HNRNPA1/RAN/NUTF2/SRSF7/CCT8/CCT5/CCT6A/ALYREF/MAGOH/SSB/RBM8A/EIF4A3/NHP2/HNRNPA3/CCT7/CCT3/TCP1/CCT2/HNRNPA2B1/THOC6/MAGOHB/NUP37/RUVBL1/PIH1D1/SMG1 28 GO:1904874 positive regulation of telomerase RNA localization to Cajal body 9/566 15/18722 8.43215539400328e-11 2.88768890877712e-08 CCT8/CCT5/CCT6A/NHP2/CCT7/CCT3/TCP1/CCT2/RUVBL1 9 GO:0042255 ribosome assembly 15/566 61/18722 2.61826958056179e-10 8.3260972661865e-08 RPL23A/NPM1/RPL6/RPL5/RPL3/RPLP0/RPSA/RPL24/RPL11/RPS19/RPL10/RPS5/RPL38/MRPS7/EIF2A 15 GO:1904872 regulation of telomerase RNA localization to Cajal body 9/566 18/18722 7.55143087131742e-10 2.24126468260701e-07 CCT8/CCT5/CCT6A/NHP2/CCT7/CCT3/TCP1/CCT2/RUVBL1 9 GO:0090670 RNA localization to Cajal body 9/566 19/18722 1.39641706519146e-09 3.27202567064862e-07 CCT8/CCT5/CCT6A/NHP2/CCT7/CCT3/TCP1/CCT2/RUVBL1 9 GO:0090671 telomerase RNA localization to Cajal body 9/566 19/18722 1.39641706519146e-09 3.27202567064862e-07 CCT8/CCT5/CCT6A/NHP2/CCT7/CCT3/TCP1/CCT2/RUVBL1 9 GO:0090672 telomerase RNA localization 9/566 19/18722 1.39641706519146e-09 3.27202567064862e-07 CCT8/CCT5/CCT6A/NHP2/CCT7/CCT3/TCP1/CCT2/RUVBL1 9 GO:0090685 RNA localization to nucleus 9/566 19/18722 1.39641706519146e-09 3.27202567064862e-07 CCT8/CCT5/CCT6A/NHP2/CCT7/CCT3/TCP1/CCT2/RUVBL1 9 GO:1904851 positive regulation of establishment of protein localization to telomere 7/566 10/18722 2.46746650990633e-09 5.3747535369687e-07 CCT8/CCT5/CCT6A/CCT7/CCT3/TCP1/CCT2 7 GO:0000723 telomere maintenance 20/566 131/18722 2.53526110234372e-09 5.3747535369687e-07 HNRNPA1/HSP90AB1/PKIB/CCT8/CCT5/HNRNPC/CCT6A/PTGES3/CCNE1/RPA3/NHP2/CCT7/CCT3/TCP1/HNRNPD/CCT2/HNRNPA2B1/TPRKB/RAD51/SMG1 20 GO:0048002 antigen processing and presentation of peptide antigen 14/566 62/18722 3.4739348950528e-09 7.02998097853413e-07 CD74/HLA-B/HLA-C/HLA-DRB1/FCER1G/HLA-DPA1/HLA-A/HLA-DRA/HLA-DPB1/LGMN/B2M/CTSD/CTSF/CALR 14 GO:0050821 protein stabilization 24/566 191/18722 3.74234897558887e-09 7.24388593013984e-07 GAPDH/NPM1/PFN1/RPL5/RPL23/HSP90AB1/TYROBP/RPL11/CCT8/CCT5/CCT6A/PTGES3/PARK7/CCT7/CCT3/TCP1/CCT2/HSPD1/BAG2/GRN/PDCD10/PLPP3/P3H1/CALR 24 GO:0006364 rRNA processing 26/566 225/18722 5.07905515941295e-09 9.42164732071101e-07 RPS6/RPL7/RPS8/RPS16/RPL7A/RPL26/RPL14/RPL5/RPS17/PA2G4/LSM6/RPL10A/RPL11/RPL27/RPS19/EBNA1BP2/EIF4A3/TRMT112/RPS25/NHP2/NIFK/RSL1D1/FRG1/PIH1D1/RPL7L1/EXOSC9 26 GO:0070203 regulation of establishment of protein localization to telomere 7/566 11/18722 6.60839248383216e-09 1.08965049400077e-06 CCT8/CCT5/CCT6A/CCT7/CCT3/TCP1/CCT2 7 GO:1904869 regulation of protein localization to Cajal body 7/566 11/18722 6.60839248383216e-09 1.08965049400077e-06 CCT8/CCT5/CCT6A/CCT7/CCT3/TCP1/CCT2 7 GO:1904871 positive regulation of protein localization to Cajal body 7/566 11/18722 6.60839248383216e-09 1.08965049400077e-06 CCT8/CCT5/CCT6A/CCT7/CCT3/TCP1/CCT2 7 GO:0002478 antigen processing and presentation of exogenous peptide antigen 11/566 38/18722 1.00393991810153e-08 1.57568767148025e-06 CD74/HLA-DRB1/FCER1G/HLA-DPA1/HLA-A/HLA-DRA/HLA-DPB1/LGMN/B2M/CTSD/CTSF 11 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 10/566 30/18722 1.02639134036225e-08 1.57568767148025e-06 CD74/HLA-DRB1/FCER1G/HLA-DPA1/HLA-DRA/HLA-DPB1/LGMN/B2M/CTSD/CTSF 10 GO:0016072 rRNA metabolic process 26/566 236/18722 1.38526597631903e-08 2.02255184219196e-06 RPS6/RPL7/RPS8/RPS16/RPL7A/RPL26/RPL14/RPL5/RPS17/PA2G4/LSM6/RPL10A/RPL11/RPL27/RPS19/EBNA1BP2/EIF4A3/TRMT112/RPS25/NHP2/NIFK/RSL1D1/FRG1/PIH1D1/RPL7L1/EXOSC9 26 GO:0070202 regulation of establishment of protein localization to chromosome 7/566 12/18722 1.54462629457607e-08 2.02255184219196e-06 CCT8/CCT5/CCT6A/CCT7/CCT3/TCP1/CCT2 7 GO:1903405 protein localization to nuclear body 7/566 12/18722 1.54462629457607e-08 2.02255184219196e-06 CCT8/CCT5/CCT6A/CCT7/CCT3/TCP1/CCT2 7 GO:1904816 positive regulation of protein localization to chromosome, telomeric region 7/566 12/18722 1.54462629457607e-08 2.02255184219196e-06 CCT8/CCT5/CCT6A/CCT7/CCT3/TCP1/CCT2 7 GO:1904867 protein localization to Cajal body 7/566 12/18722 1.54462629457607e-08 2.02255184219196e-06 CCT8/CCT5/CCT6A/CCT7/CCT3/TCP1/CCT2 7 GO:0010833 telomere maintenance via telomere lengthening 15/566 81/18722 1.73052985342315e-08 2.20123397355425e-06 HNRNPA1/HSP90AB1/PKIB/CCT8/CCT5/HNRNPC/CCT6A/PTGES3/NHP2/CCT7/CCT3/TCP1/CCT2/HNRNPA2B1/RAD51 15 GO:0044403 biological process involved in symbiotic interaction 29/566 290/18722 1.82803964910647e-08 2.25011336644479e-06 FN1/GAPDH/CD74/APOE/LGALS1/HLA-DRB1/HSP90AB1/RPSA/PPIA/EGFR/ALYREF/CDK1/GPX1/IFITM2/CFL1/TCP1/HSPD1/ITGAV/NRP1/ITGB1/SLC52A1/DAG1/CD46/THOC6/DPP4/P4HB/TFRC/SLC1A5/CTSB 29 GO:2000278 regulation of DNA biosynthetic process 17/566 106/18722 1.87004030903992e-08 2.25011336644479e-06 HNRNPA1/HSP90AB1/PKIB/CCT8/CCT5/HNRNPC/CCT6A/PTGES3/CCT7/CCT3/TCP1/HNRNPD/RFC2/CCT2/HNRNPA2B1/RFC3/GJA1 17 GO:0140694 non-membrane-bounded organelle assembly 33/566 367/18722 2.62367918964767e-08 3.07384730323985e-06 RPL23A/KRT19/NPM1/RPL6/RPS3/RPL5/RPL3/RPLP0/ACTG1/CSRP2/RPSA/LSM3/RPL24/RPL11/LSM4/RPS19/RPL10/RPS5/HAUS1/CHMP5/KRT8/CENPK/RPL38/CENPN/CIRBP/MRPS7/ITGB1/CCNB2/CDC20/HAUS8/CENPH/EIF2A/TUBGCP2 33 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 10/566 34/18722 4.01666339671914e-08 4.58517575440862e-06 CD74/HLA-DRB1/FCER1G/HLA-DPA1/HLA-DRA/HLA-DPB1/LGMN/B2M/CTSD/CTSF 10 GO:0051438 regulation of ubiquitin-protein transferase activity 12/566 53/18722 4.46765993985054e-08 4.97250551305365e-06 RPL5/RPL23/RPS2/RPS20/UBE2L3/RPL11/MAD2L1/UBE2N/PARK7/BAG2/UBE2S/CDC20 12 GO:0051054 positive regulation of DNA metabolic process 23/566 201/18722 4.69855443488032e-08 5.01627809121265e-06 RPS3/HNRNPA1/HMGB1/HSP90AB1/PKIB/CCT8/UBE2N/CCT5/CCT6A/EGFR/PTGES3/CCT7/CCT3/TCP1/HNRNPD/RFC2/CCT2/ANXA3/HNRNPA2B1/RFC3/RAD51/UBE2V2/TFRC 23 GO:1900182 positive regulation of protein localization to nucleus 15/566 87/18722 4.73233782189872e-08 5.01627809121265e-06 NPM1/RAN/HSP90AB1/NUTF2/CDH1/CCT8/CCT5/CCT6A/CDK1/PARK7/CCT7/CCT3/TCP1/CCT2/TFRC 15 GO:0000027 ribosomal large subunit assembly 9/566 27/18722 5.70543172151065e-08 5.90711209864312e-06 RPL23A/RPL6/RPL5/RPL3/RPLP0/RPL24/RPL11/RPL10/RPL38 9 GO:1904814 regulation of protein localization to chromosome, telomeric region 7/566 14/18722 6.34880198248903e-08 6.28108142800915e-06 CCT8/CCT5/CCT6A/CCT7/CCT3/TCP1/CCT2 7 GO:1990173 protein localization to nucleoplasm 7/566 14/18722 6.34880198248903e-08 6.28108142800915e-06 CCT8/CCT5/CCT6A/CCT7/CCT3/TCP1/CCT2 7 GO:0051099 positive regulation of binding 21/566 173/18722 6.49802445409128e-08 6.28895758035095e-06 APOE/RAN/HMGB2/HMGB1/CALM1/EIF3E/HSP90AB1/LRP1/RPL11/STMN1/NME1/ISL1/B2M/PARK7/S100A10/TXN/GMNN/AMFR/MET/NRP1/APP 21 GO:2000573 positive regulation of DNA biosynthetic process 13/566 66/18722 7.23413998446741e-08 6.69901581886755e-06 HNRNPA1/HSP90AB1/PKIB/CCT8/CCT5/CCT6A/PTGES3/CCT7/CCT3/TCP1/RFC2/CCT2/RFC3 13 GO:0032200 telomere organization 20/566 159/18722 7.36011007718542e-08 6.69901581886755e-06 HNRNPA1/HSP90AB1/PKIB/CCT8/CCT5/HNRNPC/CCT6A/PTGES3/CCNE1/RPA3/NHP2/CCT7/CCT3/TCP1/HNRNPD/CCT2/HNRNPA2B1/TPRKB/RAD51/SMG1 20 GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 10/566 36/18722 7.37313061825044e-08 6.69901581886755e-06 CD74/HLA-DRB1/FCER1G/HLA-DPA1/HLA-DRA/HLA-DPB1/LGMN/B2M/CTSD/CTSF 10 GO:1904358 positive regulation of telomere maintenance via telomere lengthening 10/566 37/18722 9.83237161800214e-08 8.7547436886691e-06 HNRNPA1/PKIB/CCT8/CCT5/CCT6A/CCT7/CCT3/TCP1/CCT2/HNRNPA2B1 10 GO:0019884 antigen processing and presentation of exogenous antigen 11/566 47/18722 1.1352484864092e-07 9.91005149312505e-06 CD74/HLA-DRB1/FCER1G/HLA-DPA1/HLA-A/HLA-DRA/HLA-DPB1/LGMN/B2M/CTSD/CTSF 11 GO:0007004 telomere maintenance via telomerase 13/566 69/18722 1.25844076850907e-07 1.07741890411584e-05 HNRNPA1/HSP90AB1/PKIB/CCT8/CCT5/HNRNPC/CCT6A/PTGES3/NHP2/CCT7/CCT3/TCP1/CCT2 13 GO:0071897 DNA biosynthetic process 21/566 180/18722 1.29212217065462e-07 1.08538262334988e-05 HNRNPA1/HSP90AB1/TYMS/PKIB/CCT8/CCT5/HNRNPC/CCT6A/PTGES3/NHP2/TK1/CCT7/CCT3/TCP1/HNRNPD/POLE3/RFC2/CCT2/HNRNPA2B1/RFC3/GJA1 21 GO:0051052 regulation of DNA metabolic process 31/566 359/18722 1.73115188259558e-07 1.42723855209547e-05 NPM1/RPS3/HNRNPA1/HMGB1/HSP90AB1/PKIB/CCT8/UBE2N/CCT5/HNRNPC/SUB1/CCT6A/EGFR/PTGES3/ALYREF/DEK/CCT7/CCT3/TCP1/HNRNPD/RFC2/CCT2/ANXA3/HNRNPA2B1/RFC3/RAD51/PPP4C/GJA1/UBE2V2/SMG1/TFRC 31 GO:0070200 establishment of protein localization to telomere 7/566 16/18722 2.0074050967015e-07 1.62490318009365e-05 CCT8/CCT5/CCT6A/CCT7/CCT3/TCP1/CCT2 7 GO:1904666 regulation of ubiquitin protein ligase activity 8/566 23/18722 2.18092098390358e-07 1.73383218220335e-05 RPL5/RPL23/RPS20/RPL11/MAD2L1/BAG2/UBE2S/CDC20 8 GO:0051701 biological process involved in interaction with host 22/566 203/18722 2.40796107827402e-07 1.88074433692561e-05 CD74/LGALS1/HLA-DRB1/RPSA/PPIA/EGFR/ALYREF/CDK1/IFITM2/TCP1/ITGAV/NRP1/ITGB1/SLC52A1/DAG1/CD46/THOC6/DPP4/P4HB/TFRC/SLC1A5/CTSB 22 GO:2001234 negative regulation of apoptotic signaling pathway 23/566 224/18722 3.4145300456409e-07 2.59055615078287e-05 TPT1/CD74/MIF/HMGB2/VDAC2/YBX3/ENO1/SLC25A5/DNAJA1/PPIA/GSTP1/GPX1/PARK7/ITGA6/TRIAP1/GHITM/ITGAV/NRP1/NDUFS3/GNAI3/PIH1D1/SERPINE1/FAIM 23 GO:0032206 positive regulation of telomere maintenance 11/566 52/18722 3.43312697430794e-07 2.59055615078287e-05 HNRNPA1/PKIB/CCT8/CCT5/CCT6A/CCT7/CCT3/TCP1/HNRNPD/CCT2/HNRNPA2B1 11 GO:0006278 RNA-dependent DNA biosynthetic process 13/566 75/18722 3.49194162121373e-07 2.59102068294059e-05 HNRNPA1/HSP90AB1/PKIB/CCT8/CCT5/HNRNPC/CCT6A/PTGES3/NHP2/CCT7/CCT3/TCP1/CCT2 13 GO:0046718 viral entry into host cell 18/566 144/18722 3.62711146146694e-07 2.64719675843456e-05 CD74/LGALS1/HLA-DRB1/RPSA/EGFR/CDK1/IFITM2/ITGAV/NRP1/ITGB1/SLC52A1/DAG1/CD46/DPP4/P4HB/TFRC/SLC1A5/CTSB 18 GO:0070199 establishment of protein localization to chromosome 8/566 25/18722 4.56038825919044e-07 3.2746529886961e-05 CCT8/CCT5/CCT6A/CCT7/CCT3/TCP1/CCT2/PIH1D1 8 GO:0032212 positive regulation of telomere maintenance via telomerase 9/566 34/18722 5.2849466683385e-07 3.73469564562587e-05 HNRNPA1/PKIB/CCT8/CCT5/CCT6A/CCT7/CCT3/TCP1/CCT2 9 GO:1904667 negative regulation of ubiquitin protein ligase activity 6/566 12/18722 5.88361215640275e-07 4.09278770629766e-05 RPL5/RPL23/RPS20/RPL11/MAD2L1/BAG2 6 GO:0051098 regulation of binding 30/566 363/18722 6.9628367057341e-07 4.76900754060434e-05 APOE/RAN/HMGB2/HMGB1/CALM1/EIF3E/HSP90AB1/LRP1/RPL11/C4orf3/STMN1/PTPRF/NME1/ISL1/PPP1CA/B2M/EIF4A3/PARK7/S100A10/TXN/GMNN/AMFR/MET/TMSB4X/BAG2/NRP1/ZNF593/APP/SRI/GTF2F1 30 GO:0044409 entry into host 18/566 151/18722 7.39271990770742e-07 4.98672561047173e-05 CD74/LGALS1/HLA-DRB1/RPSA/EGFR/CDK1/IFITM2/ITGAV/NRP1/ITGB1/SLC52A1/DAG1/CD46/DPP4/P4HB/TFRC/SLC1A5/CTSB 18 GO:0032204 regulation of telomere maintenance 13/566 80/18722 7.57074172843032e-07 5.03058838432415e-05 HNRNPA1/PKIB/CCT8/CCT5/HNRNPC/CCT6A/CCT7/CCT3/TCP1/HNRNPD/CCT2/HNRNPA2B1/SMG1 13 GO:0051444 negative regulation of ubiquitin-protein transferase activity 7/566 19/18722 8.16897346475906e-07 5.34827498016284e-05 RPL5/RPL23/RPS20/RPL11/MAD2L1/PARK7/BAG2 7 GO:0033044 regulation of chromosome organization 20/566 187/18722 1.04368096051297e-06 6.73401106696196e-05 HNRNPA1/PKIB/CCT8/MAD2L1/CCT5/HNRNPC/CCT6A/CCNB1/BUB3/CCT7/CCT3/TCP1/HNRNPD/CCT2/PTTG1/HNRNPA2B1/ZWINT/ANAPC11/CDC26/SMG1 20 GO:0035036 sperm-egg recognition 10/566 48/18722 1.36871722020283e-06 8.70504152049001e-05 ALDOA/VDAC2/CCT8/CCT5/CCT7/CCT3/TCP1/CCT2/B4GALT1/FOLR1 10 GO:2001233 regulation of apoptotic signaling pathway 29/566 356/18722 1.4295555339113e-06 8.96391723517338e-05 TPT1/RPS3/CD74/RPL26/MIF/HMGB2/VDAC2/YBX3/ENO1/SLC25A5/DNAJA1/PPIA/RPL11/GSTP1/PPP1CA/GPX1/PARK7/ITGA6/TRIAP1/GHITM/ITGAV/NRP1/TIMP3/NDUFS3/GNAI3/PIH1D1/SERPINE1/FAIM/P4HB 29 GO:0052126 movement in host environment 19/566 175/18722 1.54306832380729e-06 9.54130580220843e-05 CD74/LGALS1/HLA-DRB1/RPSA/PPIA/EGFR/CDK1/IFITM2/ITGAV/NRP1/ITGB1/SLC52A1/DAG1/CD46/DPP4/P4HB/TFRC/SLC1A5/CTSB 19 GO:0052547 regulation of peptidase activity 34/566 461/18722 1.73204506902027e-06 0.000105631022565455 FN1/GAPDH/RPS3/CRIM1/HMGB1/LRP1/SERPINE2/SERPINB1/CYCS/PSMA3/PRDX3/BIRC5/LGMN/GPX1/PARK7/TRIAP1/SPINT1/HSPD1/PTTG1/GRN/HSPE1/UBXN1/PDCD5/PSMD14/APLP2/ITIH5/APP/SERPINF1/TIMP3/CTSD/FBLN1/PIH1D1/PDCD2/SERPINE1 34 GO:0042274 ribosomal small subunit biogenesis 12/566 73/18722 1.77560534876121e-06 0.000106824256928174 NPM1/RPS6/RPS8/RPS16/RPS17/RPSA/LSM6/RPS19/RPS25/RPS5/RPL38/MRPS7 12 GO:1904356 regulation of telomere maintenance via telomere lengthening 11/566 61/18722 1.85763214507286e-06 0.000110269044131525 HNRNPA1/PKIB/CCT8/CCT5/HNRNPC/CCT6A/CCT7/CCT3/TCP1/CCT2/HNRNPA2B1 11 GO:0050657 nucleic acid transport 18/566 163/18722 2.26928747104868e-06 0.000131206075598815 NPM1/SRSF3/YBX1/HNRNPA1/RAN/NUTF2/SRSF7/ALYREF/MAGOH/SSB/RBM8A/EIF4A3/HNRNPA3/HNRNPA2B1/THOC6/MAGOHB/NUP37/SMG1 18 GO:0050658 RNA transport 18/566 163/18722 2.26928747104868e-06 0.000131206075598815 NPM1/SRSF3/YBX1/HNRNPA1/RAN/NUTF2/SRSF7/ALYREF/MAGOH/SSB/RBM8A/EIF4A3/HNRNPA3/HNRNPA2B1/THOC6/MAGOHB/NUP37/SMG1 18 GO:0007339 binding of sperm to zona pellucida 9/566 40/18722 2.34354407780499e-06 0.000132069091574529 ALDOA/VDAC2/CCT8/CCT5/CCT7/CCT3/TCP1/CCT2/B4GALT1 9 GO:1901998 toxin transport 9/566 40/18722 2.34354407780499e-06 0.000132069091574529 DNAJA1/CCT8/CCT5/CCT7/CCT3/TCP1/CCT2/NRP1/BNIP3 9 GO:0006417 regulation of translation 34/566 468/18722 2.41832678177544e-06 0.000134579885405803 GAPDH/NPM1/RPS3/RPL26/RPL5/RPS4X/RPL13A/YBX1/VIM/EIF3E/YBX3/PA2G4/TYMS/PKM/EIF3H/SRP9/NCL/MAGOH/PPP1CA/RBM8A/EIF4A3/RPL10/HNRNPD/RPL38/EIF1/CIRBP/RPS9/APP/MRPL13/PLXNB2/MALSU1/EIF2A/EXOSC9/CALR 34 GO:0006091 generation of precursor metabolites and energy 35/566 490/18722 2.51802335169558e-06 0.00013671024343596 GAPDH/LDHA/HMGB1/TPI1/ALDOA/ENO1/IL6ST/PKM/CYBA/UQCRH/CYCS/ETFB/CCNB1/PTGES3/MDH1/CDK1/PPP1CA/UGP2/COX4I1/PARK7/NDUFB3/MDH2/GHITM/COX7A2L/STOML2/CHCHD2/SDHB/NDUFA10/BNIP3/APP/COX5A/IGF2/GAA/FH/NDUFS3 35 GO:0010498 proteasomal protein catabolic process 35/566 490/18722 2.51802335169558e-06 0.00013671024343596 APOE/PSMA2/HSP90AB1/EIF3H/RPL11/PSMA5/PSMA3/PSMD4/PSMD8/GPX1/SUMO2/PARK7/DDA1/PSMA4/PSMB1/AMFR/BAG2/PBK/UBE2S/GABARAP/UBXN1/CDC20/PSMD14/PSMC4/PSMA7/ANAPC11/HSP90B1/CDC26/CANX/NHLRC3/NUDT15/UBE2V2/EDEM3/TMEM259/CALR 35 GO:0006413 translational initiation 15/566 118/18722 2.74647560806711e-06 0.000147316980808611 RPS3A/NPM1/RPS3/RPS17/RPL13A/EIF3E/EIF3H/PPP1CA/RPS5/EIF1/EIF1AX/EIF2S2/EIF3I/EIF2A/COPS5 15 GO:0051236 establishment of RNA localization 18/566 166/18722 2.95106753360894e-06 0.000156406579281274 NPM1/SRSF3/YBX1/HNRNPA1/RAN/NUTF2/SRSF7/ALYREF/MAGOH/SSB/RBM8A/EIF4A3/HNRNPA3/HNRNPA2B1/THOC6/MAGOHB/NUP37/SMG1 18 GO:0042176 regulation of protein catabolic process 30/566 391/18722 3.21324629494833e-06 0.000166505935874351 LRP2/RPL5/RPL23/APOE/EEF1A1/HSP90AB1/LRP1/EIF3H/RPL11/CDH1/SERPINE2/MAD2L1/EGFR/OAZ1/GPX1/SUMO2/PARK7/DDA1/BAG2/PBK/GABARAP/UBXN1/CDC20/PSMD14/PSMC4/TIMP3/GJA1/NUDT15/UBE2V2/TMEM259 30 GO:0031960 response to corticosteroid 18/566 167/18722 3.21642194186752e-06 0.000166505935874351 HMGB1/CALM1/ANXA1/TYMS/UBE2L3/CYBA/GSTP1/EGFR/ISL1/RPL27/SPARC/ANXA3/HSPD1/ENG/AIF1/SERPINF1/ATP2B1/GLB1 18 GO:0032210 regulation of telomere maintenance via telomerase 10/566 53/18722 3.56227195718004e-06 0.000182290054636386 HNRNPA1/PKIB/CCT8/CCT5/HNRNPC/CCT6A/CCT7/CCT3/TCP1/CCT2 10 GO:0019882 antigen processing and presentation 14/566 106/18722 3.72591303044943e-06 0.000188497327404101 CD74/HLA-B/HLA-C/HLA-DRB1/FCER1G/HLA-DPA1/HLA-A/HLA-DRA/HLA-DPB1/LGMN/B2M/CTSD/CTSF/CALR 14 GO:0015931 nucleobase-containing compound transport 21/566 222/18722 4.11804683395593e-06 0.000205994882076088 NPM1/SRSF3/YBX1/HNRNPA1/RAN/NUTF2/SLC25A5/SRSF7/ALYREF/MAGOH/SSB/RBM8A/EIF4A3/HNRNPA3/SLC19A1/HNRNPA2B1/THOC6/MAGOHB/NUP37/GJA1/SMG1 21 GO:0015980 energy derivation by oxidation of organic compounds 26/566 318/18722 4.67042387668437e-06 0.000231030301099987 HMGB1/IL6ST/UQCRH/CYCS/CCNB1/PTGES3/MDH1/CDK1/PPP1CA/UGP2/COX4I1/PARK7/NDUFB3/MDH2/GHITM/COX7A2L/STOML2/CHCHD2/SDHB/NDUFA10/BNIP3/COX5A/IGF2/GAA/FH/NDUFS3 26 GO:0009060 aerobic respiration 19/566 189/18722 4.86388354423931e-06 0.000237956148779708 UQCRH/CYCS/CCNB1/MDH1/CDK1/COX4I1/PARK7/NDUFB3/MDH2/GHITM/COX7A2L/STOML2/CHCHD2/SDHB/NDUFA10/BNIP3/COX5A/FH/NDUFS3 19 GO:0042773 ATP synthesis coupled electron transport 13/566 95/18722 5.54251038828938e-06 0.000265325336007143 UQCRH/CYCS/CCNB1/CDK1/COX4I1/PARK7/NDUFB3/GHITM/COX7A2L/CHCHD2/NDUFA10/COX5A/NDUFS3 13 GO:0042775 mitochondrial ATP synthesis coupled electron transport 13/566 95/18722 5.54251038828938e-06 0.000265325336007143 UQCRH/CYCS/CCNB1/CDK1/COX4I1/PARK7/NDUFB3/GHITM/COX7A2L/CHCHD2/NDUFA10/COX5A/NDUFS3 13 GO:0048678 response to axon injury 12/566 83/18722 7.10780728064117e-06 0.000336637851206537 SPP1/LGALS1/TYROBP/LRP1/PTPRF/ISL1/CDK1/GRN/DAG1/BNIP3/AIF1/FOLR1 12 GO:0051235 maintenance of location 26/566 326/18722 7.30359586896365e-06 0.000342269566406591 FBN2/FBN1/PLIN2/FTL/APOE/CALM1/CYBA/SRGN/TMSB10/PARK7/TXN/ITGAV/TMSB4X/AKAP9/GSTO1/ABCA1/HSP90B1/GAA/HEXB/SRI/VPS13C/SCIN/GJA1/P2RY6/CALR/GM2A 26 GO:0001667 ameboidal-type cell migration 33/566 475/18722 8.72932303924442e-06 0.000402934947492208 FN1/PFN1/APOE/LAMA5/HMGB1/ANXA1/ATP2B4/FSTL1/ISL1/SPARC/LGMN/GPX1/SEMA6D/SEMA3F/RAB25/ANXA3/S100P/MET/TMSB4X/NRP1/ITGB1/GRN/PDCD10/ITGB4/SERPINF1/DPP4/PLPP3/LRP5/MACF1/GJA1/FOLR1/SEMA6A/CALR 33 GO:0022904 respiratory electron transport chain 14/566 114/18722 8.83191891694071e-06 0.000402934947492208 UQCRH/CYCS/CCNB1/CDK1/COX4I1/PARK7/NDUFB3/GHITM/COX7A2L/CHCHD2/SDHB/NDUFA10/COX5A/NDUFS3 14 GO:0019883 antigen processing and presentation of endogenous antigen 7/566 26/18722 8.86963720894797e-06 0.000402934947492208 CD74/HLA-B/HLA-C/HLA-DRB1/HLA-A/HLA-DRA/B2M 7 GO:0045861 negative regulation of proteolysis 27/566 351/18722 9.48620793182302e-06 0.000426591896085617 GAPDH/RPL5/RPL23/CRIM1/HSP90AB1/LRP1/EIF3H/RPL11/SERPINE2/SERPINB1/PRDX3/BIRC5/GPX1/PARK7/TRIAP1/SPINT1/PTTG1/PBK/UBXN1/APLP2/ITIH5/APP/SERPINF1/TIMP3/GLG1/PIH1D1/SERPINE1 27 GO:0002501 peptide antigen assembly with MHC protein complex 6/566 18/18722 1.01214306677699e-05 0.000450606093329115 HLA-DRB1/HLA-DPA1/HLA-DRA/HLA-DPB1/B2M/CALR 6 GO:0016032 viral process 30/566 415/18722 1.04308024481657e-05 0.000459781509893401 CD74/APOE/LGALS1/RAN/HLA-DRB1/HSP90AB1/RPSA/PPIA/EGFR/BANF1/SSB/CDK1/DEK/CHMP5/IFITM2/CFL1/ITGAV/NRP1/ITGB1/SLC52A1/PPIH/DAG1/CD46/DPP4/CANX/MOGS/P4HB/TFRC/SLC1A5/CTSB 30 GO:1903362 regulation of cellular protein catabolic process 22/566 255/18722 1.08057849054128e-05 0.000467349187971746 LRP2/RPL5/RPL23/APOE/HSP90AB1/LRP1/EIF3H/RPL11/GPX1/SUMO2/PARK7/DDA1/BAG2/PBK/GABARAP/UBXN1/CDC20/PSMD14/PSMC4/NUDT15/UBE2V2/TMEM259 22 GO:0045785 positive regulation of cell adhesion 31/566 437/18722 1.08332355581647e-05 0.000467349187971746 FN1/RPS3/CD74/LGALS1/HMGB1/HLA-DRB1/HLA-DPA1/HLA-A/ANXA1/HLA-DRA/HLA-DPB1/IL6ST/B2M/ADGRG1/ITGA6/S100A10/ARPC2/HSPD1/ITGAV/NRP1/DAG1/CD46/AIF1/DPP4/IGF2/PLPP3/IQGAP1/ZFHX3/P4HB/TFRC/CALR 31 GO:0034470 ncRNA processing 29/566 395/18722 1.09174113991603e-05 0.000467349187971746 RPS6/RPL7/RPS8/RPS16/RPL7A/RPL26/RPL14/RPL5/RPS17/PA2G4/LSM6/RPL10A/RPL11/RPL27/SSB/RPS19/EBNA1BP2/EIF4A3/TRMT112/RPS25/NHP2/NIFK/HNRNPA2B1/TPRKB/RSL1D1/FRG1/PIH1D1/RPL7L1/EXOSC9 29 GO:1903829 positive regulation of cellular protein localization 23/566 276/18722 1.20738318064928e-05 0.000511930468595293 NPM1/RAN/HSP90AB1/TYROBP/NUTF2/ATP2B4/LRP1/UBE2L3/CDH1/CCT8/CCT5/CCT6A/EGFR/CDK1/PARK7/CCT7/CCT3/TCP1/CCT2/ITGB1/PDCD5/IQGAP1/TFRC 23 GO:0044706 multi-multicellular organism process 20/566 220/18722 1.25698358017482e-05 0.000527933103673423 SPP1/SERPINE2/SLC2A1/PRDX3/HPGD/SLC6A4/SLC19A1/SLC38A2/RPL29/STS/UMPS/B4GALT1/ITGB4/DAZAP1/HEXB/PRLR/FBLN1/GJA1/CALR/CTSB 20 GO:0019058 viral life cycle 25/566 317/18722 1.32330185180195e-05 0.000550592508805821 CD74/APOE/LGALS1/HLA-DRB1/HSP90AB1/RPSA/PPIA/EGFR/BANF1/CDK1/DEK/CHMP5/IFITM2/ITGAV/NRP1/ITGB1/SLC52A1/PPIH/DAG1/CD46/DPP4/P4HB/TFRC/SLC1A5/CTSB 25 GO:1903050 regulation of proteolysis involved in cellular protein catabolic process 20/566 221/18722 1.34390132705228e-05 0.000553985991484884 RPL5/RPL23/APOE/HSP90AB1/EIF3H/RPL11/GPX1/SUMO2/PARK7/DDA1/BAG2/PBK/GABARAP/UBXN1/CDC20/PSMD14/PSMC4/NUDT15/UBE2V2/TMEM259 20 GO:0031647 regulation of protein stability 24/566 298/18722 1.38846846972381e-05 0.000567106571303708 GAPDH/NPM1/PFN1/RPL5/RPL23/HSP90AB1/TYROBP/RPL11/CCT8/CCT5/CCT6A/PTGES3/PARK7/CCT7/CCT3/TCP1/CCT2/HSPD1/BAG2/GRN/PDCD10/PLPP3/P3H1/CALR 24 GO:0000302 response to reactive oxygen species 20/566 222/18722 1.43618812345393e-05 0.000573029268822976 LDHA/RPS3/APOE/ANXA1/PRDX1/GSTP1/EGFR/PRDX3/CDK1/GPX1/PARK7/HBA2/TXN/HSPD1/MET/PDCD10/BNIP3/HBB/NUDT15/TXNIP 20 GO:0002396 MHC protein complex assembly 6/566 19/18722 1.44158306622132e-05 0.000573029268822976 HLA-DRB1/HLA-DPA1/HLA-DRA/HLA-DPB1/B2M/CALR 6 GO:0002483 antigen processing and presentation of endogenous peptide antigen 6/566 19/18722 1.44158306622132e-05 0.000573029268822976 HLA-B/HLA-C/HLA-DRB1/HLA-A/HLA-DRA/B2M 6 GO:0048545 response to steroid hormone 26/566 339/18722 1.45738913849167e-05 0.000574185526067692 SPP1/HMGB2/HMGB1/CALM1/ANXA1/DNAJA1/TYMS/UBE2L3/CYBA/GSTP1/EGFR/PTGES3/ISL1/RPL27/SPARC/PARK7/ANXA3/HSPD1/ENG/AIF1/SERPINF1/PAQR7/ATP2B1/GLB1/TXNIP/CALR 26 GO:1904951 positive regulation of establishment of protein localization 25/566 319/18722 1.47306230523165e-05 0.000575269594990467 DYNLL1/RAN/HLA-DRB1/HSP90AB1/NUTF2/PPIA/LRP1/UBE2L3/CDH1/CCT8/CCT5/CCT6A/EGFR/ISL1/PHPT1/CDK1/OAZ1/CCT7/CCT3/TCP1/CCT2/PDCD10/PDCD5/SRI/GJA1 25 GO:0000470 maturation of LSU-rRNA 7/566 28/18722 1.51480415293726e-05 0.000586426790337104 RPL7/RPL7A/RPL10A/NHP2/NIFK/RSL1D1/RPL7L1 7 GO:0061136 regulation of proteasomal protein catabolic process 18/566 187/18722 1.56563271346468e-05 0.000600879037960754 APOE/HSP90AB1/EIF3H/RPL11/GPX1/SUMO2/PARK7/DDA1/BAG2/PBK/GABARAP/UBXN1/CDC20/PSMD14/PSMC4/NUDT15/UBE2V2/TMEM259 18 GO:1900180 regulation of protein localization to nucleus 15/566 136/18722 1.59310339779394e-05 0.000606196267263131 NPM1/RAN/HSP90AB1/NUTF2/CDH1/CCT8/CCT5/CCT6A/CDK1/PARK7/CCT7/CCT3/TCP1/CCT2/TFRC 15 GO:1902287 semaphorin-plexin signaling pathway involved in axon guidance 5/566 12/18722 1.64759187273369e-05 0.000621616865882235 PLXNA1/SEMA3F/PLXNB1/NRP1/PLXNB2 5 GO:0070198 protein localization to chromosome, telomeric region 7/566 29/18722 1.94503860858784e-05 0.000727673267683452 CCT8/CCT5/CCT6A/CCT7/CCT3/TCP1/CCT2 7 GO:0071526 semaphorin-plexin signaling pathway 8/566 40/18722 2.17387886968528e-05 0.000806509060653237 PLXNA1/SEMA6D/SEMA3F/PLXNB1/MET/NRP1/PLXNB2/SEMA6A 8 GO:0031396 regulation of protein ubiquitination 19/566 210/18722 2.20441730269229e-05 0.000811079820792237 NPM1/RPS3/RPL5/RPL23/RPS2/RPS20/HSP90AB1/DNAJA1/PPIA/UBE2L3/RPL11/MAD2L1/UBE2N/PARK7/BAG2/UBE2S/GABARAP/UBXN1/CDC20 19 GO:1902285 semaphorin-plexin signaling pathway involved in neuron projection guidance 5/566 13/18722 2.61079096840371e-05 0.00095272470420765 PLXNA1/SEMA3F/PLXNB1/NRP1/PLXNB2 5 GO:0051651 maintenance of location in cell 19/566 213/18722 2.68680093948735e-05 0.000972490876633959 FTL/APOE/CALM1/CYBA/SRGN/TMSB10/PARK7/TXN/TMSB4X/AKAP9/GSTO1/HSP90B1/GAA/SRI/VPS13C/SCIN/GJA1/P2RY6/CALR 19 GO:0031099 regeneration 18/566 198/18722 3.38310589827602e-05 0.00121464414992942 RPS16/SPP1/ANXA1/LRP1/TYMS/GSTP1/PTPRF/CCNB1/EGFR/ISL1/CDK1/RPL19/GPX1/ANXA3/GRN/DAG1/CCNA2/FOLR1 18 GO:2001252 positive regulation of chromosome organization 11/566 82/18722 3.50831163962497e-05 0.00124952027356883 HNRNPA1/PKIB/CCT8/CCT5/CCT6A/CCT7/CCT3/TCP1/HNRNPD/CCT2/HNRNPA2B1 11 GO:0009988 cell-cell recognition 10/566 68/18722 3.53772736443409e-05 0.00124999700210005 ALDOA/VDAC2/CCT8/CCT5/CCT7/CCT3/TCP1/CCT2/B4GALT1/FOLR1 10 GO:0042542 response to hydrogen peroxide 15/566 146/18722 3.70571450493513e-05 0.00129904259653316 LDHA/RPS3/ANXA1/PRDX3/CDK1/GPX1/PARK7/HBA2/TXN/HSPD1/MET/PDCD10/BNIP3/HBB/TXNIP 15 GO:0046034 ATP metabolic process 22/566 277/18722 3.88453276360178e-05 0.00133912171006472 GAPDH/LDHA/TPI1/ALDOA/ENO1/PKM/UQCRH/CYCS/CCNB1/CDK1/COX4I1/PARK7/NDUFB3/GHITM/TMSB4X/COX7A2L/STOML2/CHCHD2/NDUFA10/APP/COX5A/NDUFS3 22 GO:2001242 regulation of intrinsic apoptotic signaling pathway 16/566 164/18722 3.89865304645289e-05 0.00133912171006472 TPT1/RPS3/CD74/RPL26/MIF/VDAC2/YBX3/ENO1/DNAJA1/PPIA/RPL11/GPX1/PARK7/TRIAP1/NDUFS3/P4HB 16 GO:0031397 negative regulation of protein ubiquitination 11/566 83/18722 3.93571219555788e-05 0.00133912171006472 RPS3/RPL5/RPL23/RPS20/DNAJA1/PPIA/RPL11/MAD2L1/PARK7/BAG2/UBXN1 11 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 12/566 98/18722 3.95268880544049e-05 0.00133912171006472 TPT1/CD74/MIF/VDAC2/YBX3/ENO1/DNAJA1/PPIA/GPX1/PARK7/TRIAP1/NDUFS3 12 GO:0051028 mRNA transport 14/566 130/18722 3.97044172795469e-05 0.00133912171006472 SRSF3/HNRNPA1/NUTF2/SRSF7/ALYREF/MAGOH/RBM8A/EIF4A3/HNRNPA3/HNRNPA2B1/THOC6/MAGOHB/NUP37/SMG1 14 GO:0043484 regulation of RNA splicing 15/566 148/18722 4.34502242604328e-05 0.00144358506274214 NPM1/HNRNPF/SRSF3/HNRNPA1/RPS13/SRSF7/NCL/SRSF9/MAGOH/RBM8A/AHNAK/CIRBP/SLC38A2/DAZAP1/RBM23 15 GO:0051384 response to glucocorticoid 15/566 148/18722 4.34502242604328e-05 0.00144358506274214 HMGB1/CALM1/ANXA1/TYMS/UBE2L3/GSTP1/EGFR/ISL1/SPARC/ANXA3/HSPD1/AIF1/SERPINF1/ATP2B1/GLB1 15 GO:0052548 regulation of endopeptidase activity 29/566 432/18722 5.6607761066088e-05 0.00185157242414291 GAPDH/RPS3/CRIM1/HMGB1/SERPINE2/SERPINB1/CYCS/PSMA3/PRDX3/BIRC5/LGMN/GPX1/PARK7/TRIAP1/SPINT1/HSPD1/PTTG1/HSPE1/PDCD5/PSMD14/APLP2/ITIH5/APP/SERPINF1/TIMP3/CTSD/PIH1D1/PDCD2/SERPINE1 29 GO:0007059 chromosome segregation 25/566 346/18722 5.67700405560099e-05 0.00185157242414291 RPS3/RAN/SLC25A5/MAD2L1/SPC25/CCNB1/BANF1/BIRC5/NUDC/SKA2/CCNE1/BUB3/CHMP5/CENPK/CENPN/PTTG1/ZWINT/BEX4/CDC20/ANAPC11/NUP37/CCNB1IP1/CDC26/MKI67/CENPH 25 GO:0034284 response to monosaccharide 19/566 225/18722 5.69778576162576e-05 0.00185157242414291 LDHA/LGALS1/DYNLL1/HLA-DRB1/LRP1/CYBA/GSTP1/NME1/PHPT1/SPARC/KRT18/SERPINF1/LRP5/SRI/GJA1/PIH1D1/NME2/IGF1R/TXNIP 19 GO:0050671 positive regulation of lymphocyte proliferation 14/566 137/18722 7.08888785917961e-05 0.00228693686587446 RPS3/CD74/MIF/HMGB1/HLA-DPA1/HLA-A/ANXA1/HLA-DPB1/IL6ST/CD46/AIF1/IGF2/SLC39A10/TFRC 14 GO:0045333 cellular respiration 19/566 230/18722 7.65726451848577e-05 0.00244060149721366 UQCRH/CYCS/CCNB1/MDH1/CDK1/COX4I1/PARK7/NDUFB3/MDH2/GHITM/COX7A2L/STOML2/CHCHD2/SDHB/NDUFA10/BNIP3/COX5A/FH/NDUFS3 19 GO:0032946 positive regulation of mononuclear cell proliferation 14/566 138/18722 7.67484747551465e-05 0.00244060149721366 RPS3/CD74/MIF/HMGB1/HLA-DPA1/HLA-A/ANXA1/HLA-DPB1/IL6ST/CD46/AIF1/IGF2/SLC39A10/TFRC 14 GO:0002399 MHC class II protein complex assembly 5/566 16/18722 8.21734088431072e-05 0.00257630997302474 HLA-DRB1/HLA-DPA1/HLA-DRA/HLA-DPB1/B2M 5 GO:0002503 peptide antigen assembly with MHC class II protein complex 5/566 16/18722 8.21734088431072e-05 0.00257630997302474 HLA-DRB1/HLA-DPA1/HLA-DRA/HLA-DPB1/B2M 5 GO:0034109 homotypic cell-cell adhesion 11/566 90/18722 8.38574338322621e-05 0.00261072234560301 FN1/LGALS1/ACTG1/PPIA/IL6ST/SERPINE2/MYL12A/DSC2/PLPP3/HBB/DSG2 11 GO:0022900 electron transport chain 16/566 175/18722 8.52780131089676e-05 0.00263013467845369 CYBA/UQCRH/CYCS/ETFB/CCNB1/CDK1/COX4I1/PARK7/NDUFB3/GHITM/COX7A2L/CHCHD2/SDHB/NDUFA10/COX5A/NDUFS3 16 GO:0006402 mRNA catabolic process 19/566 232/18722 8.59472364300628e-05 0.00263013467845369 NPM1/YBX1/VIM/EIF3E/YBX3/LSM6/HNRNPM/HNRNPC/MAGOH/SSB/LSM4/RBM8A/EIF4A3/LSM5/HNRNPD/CIRBP/MAGOHB/SMG1/EXOSC9 19 GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process 8/566 48/18722 8.62532935881039e-05 0.00263013467845369 RPL5/RPL23/HSP90AB1/EIF3H/RPL11/PARK7/PBK/UBXN1 8 GO:0009743 response to carbohydrate 20/566 253/18722 9.21084590851928e-05 0.00277072202599513 LDHA/LGALS1/DYNLL1/HLA-DRB1/LRP1/CYBA/GSTP1/NME1/PHPT1/SPARC/COLEC12/KRT18/SERPINF1/LRP5/SRI/GJA1/PIH1D1/NME2/IGF1R/TXNIP 20 GO:0097305 response to alcohol 20/566 253/18722 9.21084590851928e-05 0.00277072202599513 RPL15/EEF1B2/CALM1/RPL10A/TYMS/CDH1/CYBA/GSTP1/RPL27/SPARC/CDK1/HPGD/HNRNPD/RAD51/DAG1/ABCA1/PSMD14/ATP2B1/GLB1/P2RY6 20 GO:0006119 oxidative phosphorylation 14/566 141/18722 9.69305871337334e-05 0.00289620787865356 UQCRH/CYCS/CCNB1/CDK1/COX4I1/PARK7/NDUFB3/GHITM/COX7A2L/STOML2/CHCHD2/NDUFA10/COX5A/NDUFS3 14 GO:0050870 positive regulation of T cell activation 18/566 216/18722 0.000105059901005717 0.00311817786184967 RPS3/CD74/LGALS1/HMGB1/HLA-DRB1/HLA-DPA1/HLA-A/ANXA1/HLA-DRA/HLA-DPB1/IL6ST/B2M/HSPD1/CD46/AIF1/DPP4/IGF2/TFRC 18 GO:0045185 maintenance of protein location 11/566 93/18722 0.000113259259186265 0.00333927299269704 FBN2/FBN1/SRGN/TMSB10/PARK7/TXN/TMSB4X/SRI/VPS13C/SCIN/GJA1 11 GO:0010720 positive regulation of cell development 22/566 298/18722 0.00011451873124401 0.00335419336512061 FN1/LRP2/TYROBP/LRP1/IL6ST/SERPINE2/EGFR/PLXNA1/S100A10/ARPC2/SPINT1/PLXNB1/NRP1/DAG1/SERPINF1/MACF1/PLXNB2/MME/ATP6AP1/FAIM/P4HB/CALR 22 GO:0000387 spliceosomal snRNP assembly 8/566 50/18722 0.000116382615573507 0.00338650591198204 SNRPD1/SNRPF/SNRPE/LSM4/SNRPD2/SNRPB/SNRPD3/SNRPG 8 GO:0006401 RNA catabolic process 21/566 278/18722 0.000118185871707197 0.00341664610935351 NPM1/YBX1/VIM/EIF3E/YBX3/LSM6/HNRNPM/HNRNPC/MAGOH/SSB/LSM4/RBM8A/EIF4A3/LSM5/HNRNPD/CIRBP/RNASEH2A/MAGOHB/ZCCHC17/SMG1/EXOSC9 21 GO:0009895 negative regulation of catabolic process 23/566 320/18722 0.000120442736225516 0.00345942620436126 RPL5/RPL23/APOC1/YBX1/HSP90AB1/YBX3/ATP2B4/QSOX1/EIF3H/RPL11/SERPINE2/MAD2L1/HNRNPC/EGFR/PARK7/HNRNPD/CIRBP/MET/PBK/UBXN1/TIMP3/ZCCHC17/SMG1 23 GO:0001890 placenta development 14/566 144/18722 0.000121572210742007 0.00346948386040652 KRT19/RPS6/SPP1/HSP90AB1/PRDX3/KRT8/SPINT1/ITGB8/DAZAP1/IGF2/GJA1/MME/HTRA1/CTSB 14 GO:1903321 negative regulation of protein modification by small protein conjugation or removal 11/566 95/18722 0.000137400098174505 0.00389621170110125 RPS3/RPL5/RPL23/RPS20/DNAJA1/PPIA/RPL11/MAD2L1/PARK7/BAG2/UBXN1 11 GO:0009141 nucleoside triphosphate metabolic process 12/566 112/18722 0.00014660812794507 0.00409552053842695 RAN/ALDOA/ENO1/TYMS/NME1/DUT/IMPDH2/TMSB4X/STOML2/GNAI3/NUDT15/NME2 12 GO:0009636 response to toxic substance 20/566 262/18722 0.000148108447144371 0.00409552053842695 APOE/PRDX1/TYMS/CDH1/GSTP1/SRSF9/CCNB1/PRDX3/CDK1/SLC6A4/GPX1/PARK7/HBA2/MT2A/TXN/RAD51/GSTO1/GLRX/HBB/ESD 20 GO:0010466 negative regulation of peptidase activity 20/566 262/18722 0.000148108447144371 0.00409552053842695 GAPDH/CRIM1/LRP1/SERPINE2/SERPINB1/PRDX3/BIRC5/GPX1/PARK7/TRIAP1/SPINT1/PTTG1/UBXN1/APLP2/ITIH5/APP/SERPINF1/TIMP3/PIH1D1/SERPINE1 20 GO:0031330 negative regulation of cellular catabolic process 20/566 262/18722 0.000148108447144371 0.00409552053842695 RPL5/RPL23/APOC1/YBX1/HSP90AB1/YBX3/ATP2B4/QSOX1/EIF3H/RPL11/HNRNPC/PARK7/HNRNPD/CIRBP/MET/PBK/UBXN1/TIMP3/ZCCHC17/SMG1 20 GO:1903320 regulation of protein modification by small protein conjugation or removal 19/566 242/18722 0.000149741558539908 0.00411511986802267 NPM1/RPS3/RPL5/RPL23/RPS2/RPS20/HSP90AB1/DNAJA1/PPIA/UBE2L3/RPL11/MAD2L1/UBE2N/PARK7/BAG2/UBE2S/GABARAP/UBXN1/CDC20 19 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 6/566 28/18722 0.000158769522135301 0.00433645345120466 HLA-B/HLA-C/FCER1G/HLA-A/B2M/CALR 6 GO:0070663 regulation of leukocyte proliferation 19/566 245/18722 0.000175657063104655 0.00474132316569172 RPS3/CD74/MIF/HMGB1/HLA-DRB1/TYROBP/HLA-DPA1/HLA-A/ANXA1/HLA-DPB1/IL6ST/GSTP1/CD46/AIF1/GPNMB/IGF2/SLC39A10/MNDA/TFRC 19 GO:0050670 regulation of lymphocyte proliferation 18/566 225/18722 0.000175722893607173 0.00474132316569172 RPS3/CD74/MIF/HMGB1/HLA-DRB1/TYROBP/HLA-DPA1/HLA-A/ANXA1/HLA-DPB1/IL6ST/CD46/AIF1/GPNMB/IGF2/SLC39A10/MNDA/TFRC 18 GO:0070665 positive regulation of leukocyte proliferation 14/566 150/18722 0.000187519421243383 0.00502913532153941 RPS3/CD74/MIF/HMGB1/HLA-DPA1/HLA-A/ANXA1/HLA-DPB1/IL6ST/CD46/AIF1/IGF2/SLC39A10/TFRC 14 GO:0046651 lymphocyte proliferation 21/566 288/18722 0.000192948428377987 0.00514375091699879 RPS6/RPS3/CD74/MIF/HMGB1/HLA-DRB1/TYROBP/HLA-DPA1/HLA-A/ANXA1/HLA-DPB1/IL6ST/IMPDH2/HSPD1/CD46/AIF1/GPNMB/IGF2/SLC39A10/MNDA/TFRC 21 GO:0032944 regulation of mononuclear cell proliferation 18/566 227/18722 0.000196157651917744 0.00519817777582023 RPS3/CD74/MIF/HMGB1/HLA-DRB1/TYROBP/HLA-DPA1/HLA-A/ANXA1/HLA-DPB1/IL6ST/CD46/AIF1/GPNMB/IGF2/SLC39A10/MNDA/TFRC 18 GO:0000028 ribosomal small subunit assembly 5/566 19/18722 0.000202899747505164 0.00534502766800586 RPSA/RPS19/RPS5/RPL38/MRPS7 5 GO:1990748 cellular detoxification 12/566 116/18722 0.000204703589381351 0.00536082576426927 APOE/PRDX1/GSTP1/PRDX3/GPX1/PARK7/HBA2/TXN/GSTO1/GLRX/HBB/ESD 12 GO:0072594 establishment of protein localization to organelle 27/566 422/18722 0.000221752375081428 0.00575444797824364 RPL23/RAN/CALM1/HSP90AB1/NUTF2/DNAJA1/UBE2L3/SRP9/CDH1/CCT8/CCT5/CCT6A/CDK1/CCT7/CCT3/TCP1/CCT2/HSPD1/TOMM22/PDCD5/LMAN1/SRP19/TIMM9/VPS13C/PIH1D1/TXNIP/SEC61A1 27 GO:0032943 mononuclear cell proliferation 21/566 291/18722 0.000222319194128011 0.00575444797824364 RPS6/RPS3/CD74/MIF/HMGB1/HLA-DRB1/TYROBP/HLA-DPA1/HLA-A/ANXA1/HLA-DPB1/IL6ST/IMPDH2/HSPD1/CD46/AIF1/GPNMB/IGF2/SLC39A10/MNDA/TFRC 21 GO:0034975 protein folding in endoplasmic reticulum 4/566 11/18722 0.000230253559059321 0.00581581613585668 HSP90B1/CANX/P4HB/CALR 4 GO:0046598 positive regulation of viral entry into host cell 4/566 11/18722 0.000230253559059321 0.00581581613585668 CD74/LGALS1/HLA-DRB1/P4HB 4 GO:0075294 positive regulation by symbiont of entry into host 4/566 11/18722 0.000230253559059321 0.00581581613585668 CD74/LGALS1/HLA-DRB1/P4HB 4 GO:0007338 single fertilization 14/566 153/18722 0.000230740310778063 0.00581581613585668 ALDOA/VDAC2/CCT8/CCT5/CDK1/PARK7/CCT7/CCT3/TCP1/CCT2/B4GALT1/CD46/HEXB/FOLR1 14 GO:0001755 neural crest cell migration 8/566 55/18722 0.000231221800549558 0.00581581613585668 FN1/LAMA5/ISL1/SEMA6D/SEMA3F/NRP1/FOLR1/SEMA6A 8 GO:0042102 positive regulation of T cell proliferation 11/566 101/18722 0.000237675190815251 0.00587849971949721 RPS3/HMGB1/HLA-DPA1/HLA-A/ANXA1/HLA-DPB1/IL6ST/CD46/AIF1/IGF2/TFRC 11 GO:0048024 regulation of mRNA splicing, via spliceosome 11/566 101/18722 0.000237675190815251 0.00587849971949721 NPM1/SRSF3/HNRNPA1/SRSF7/NCL/SRSF9/MAGOH/RBM8A/CIRBP/DAZAP1/RBM23 11 GO:0098869 cellular oxidant detoxification 11/566 101/18722 0.000237675190815251 0.00587849971949721 APOE/PRDX1/GSTP1/PRDX3/GPX1/PARK7/HBA2/TXN/GSTO1/GLRX/HBB 11 GO:0016052 carbohydrate catabolic process 14/566 154/18722 0.000246933417885451 0.00604037129904411 GAPDH/LDHA/HMGB1/TPI1/ALDOA/ENO1/PKM/PPP1CA/APP/LRP5/GAA/HEXB/GLB1/GM2A 14 GO:0051168 nuclear export 14/566 154/18722 0.000246933417885451 0.00604037129904411 NPM1/SRSF3/HNRNPA1/RAN/NUTF2/ALYREF/SSB/PARK7/TXN/HSPA9/HNRNPA2B1/THOC6/SMG1/CALR 14 GO:0045727 positive regulation of translation 13/566 136/18722 0.000249129315522243 0.00606078531532801 NPM1/RPL26/RPL5/RPS4X/VIM/EIF3E/YBX3/PKM/EIF4A3/HNRNPD/CIRBP/RPS9/PLXNB2 13 GO:0032930 positive regulation of superoxide anion generation 5/566 20/18722 0.00026384318294983 0.00638385788311219 TYROBP/CYBA/GSTP1/EGFR/GNAI3 5 GO:0007565 female pregnancy 16/566 193/18722 0.00026558069779388 0.00639116360312625 SPP1/SLC2A1/PRDX3/HPGD/SLC19A1/SLC38A2/RPL29/STS/UMPS/ITGB4/DAZAP1/PRLR/FBLN1/GJA1/CALR/CTSB 16 GO:0070661 leukocyte proliferation 22/566 318/18722 0.000287525581124789 0.00688206390950302 RPS6/RPS3/CD74/MIF/HMGB1/HLA-DRB1/TYROBP/HLA-DPA1/HLA-A/ANXA1/HLA-DPB1/IL6ST/GSTP1/IMPDH2/HSPD1/CD46/AIF1/GPNMB/IGF2/SLC39A10/MNDA/TFRC 22 GO:0042177 negative regulation of protein catabolic process 12/566 121/18722 0.000303953874662201 0.00723637780746588 RPL5/RPL23/HSP90AB1/EIF3H/RPL11/SERPINE2/MAD2L1/EGFR/PARK7/PBK/UBXN1/TIMP3 12 GO:0009144 purine nucleoside triphosphate metabolic process 10/566 88/18722 0.000320200368260999 0.00754249756348131 RAN/ALDOA/ENO1/NME1/IMPDH2/TMSB4X/STOML2/GNAI3/NUDT15/NME2 10 GO:0010232 vascular transport 10/566 88/18722 0.000320200368260999 0.00754249756348131 LRP2/APOE/ATP2B4/LRP1/SLC2A1/SLC19A1/SLC38A2/GJA1/TFRC/SLC1A5 10 GO:0042743 hydrogen peroxide metabolic process 8/566 58/18722 0.000336263297116386 0.00781748891828697 PRDX1/CYBA/EGFR/PRDX3/GPX1/PARK7/HBA2/HBB 8 GO:0002424 T cell mediated immune response to tumor cell 4/566 12/18722 0.000337142379225314 0.00781748891828697 HMGB1/HLA-DRB1/HLA-A/HSPD1 4 GO:1903599 positive regulation of autophagy of mitochondrion 4/566 12/18722 0.000337142379225314 0.00781748891828697 VDAC1/SLC25A5/PARK7/BNIP3 4 GO:0043542 endothelial cell migration 20/566 279/18722 0.000339524662669264 0.00783193677825682 APOE/HMGB1/ANXA1/ATP2B4/FSTL1/SPARC/LGMN/GPX1/ANXA3/S100P/MET/TMSB4X/NRP1/ITGB1/GRN/PDCD10/SERPINF1/DPP4/PLPP3/CALR 20 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 26/566 412/18722 0.000356097934902923 0.00817189693911245 PSMA2/HSP90AB1/EIF3H/RPL11/PSMA5/PSMD4/PSMD8/SUMO2/PARK7/DDA1/AMFR/PBK/UBE2S/GABARAP/UBXN1/CDC20/PSMD14/PSMC4/ANAPC11/HSP90B1/CDC26/CANX/NHLRC3/UBE2V2/EDEM3/CALR 26 GO:1903039 positive regulation of leukocyte cell-cell adhesion 18/566 239/18722 0.000368126899157556 0.00840462028230482 RPS3/CD74/LGALS1/HMGB1/HLA-DRB1/HLA-DPA1/HLA-A/ANXA1/HLA-DRA/HLA-DPB1/IL6ST/B2M/HSPD1/CD46/AIF1/DPP4/IGF2/TFRC 18 GO:0006260 DNA replication 19/566 260/18722 0.000373290581428496 0.00847468252087546 PTMS/EGFR/ALYREF/CACYBP/CDK1/CCNE1/DUT/RPA3/POLE3/RFC2/RRM2/GMNN/RNASEH2A/STOML2/SUPT16H/RFC3/RAD51/CCNA2/DBF4 19 GO:0009746 response to hexose 17/566 219/18722 0.000375002797981237 0.00847468252087546 LDHA/LGALS1/DYNLL1/HLA-DRB1/LRP1/CYBA/NME1/PHPT1/KRT18/SERPINF1/LRP5/SRI/GJA1/PIH1D1/NME2/IGF1R/TXNIP 17 GO:0097237 cellular response to toxic substance 12/566 124/18722 0.000381143257648157 0.00856994839924038 APOE/PRDX1/GSTP1/PRDX3/GPX1/PARK7/HBA2/TXN/GSTO1/GLRX/HBB/ESD 12 GO:0034660 ncRNA metabolic process 29/566 485/18722 0.000406210211468896 0.00908767769577651 RPS6/RPL7/RPS8/RPS16/RPL7A/RPL26/RPL14/RPL5/RPS17/PA2G4/LSM6/RPL10A/RPL11/RPL27/SSB/RPS19/EBNA1BP2/EIF4A3/TRMT112/RPS25/NHP2/NIFK/HNRNPA2B1/TPRKB/RSL1D1/FRG1/PIH1D1/RPL7L1/EXOSC9 29 GO:0009410 response to xenobiotic stimulus 28/566 462/18722 0.000410915331668213 0.00914697528293442 LDHA/PLIN2/LGALS1/HSP90AB1/ANXA1/TYMS/CDH1/CYBA/GSTP1/NME1/CCNB1/EGFR/CDK1/SLC6A4/GPX1/B2M/S100A10/HSPD1/UMPS/RAD51/ENG/GSTO1/ABCA1/TGIF1/NUDT15/TXNIP/TFRC/CALR 28 GO:0034446 substrate adhesion-dependent cell spreading 11/566 108/18722 0.000426796719474643 0.00945322883134881 FN1/LAMA5/LAMC1/S100A10/ARPC2/LAMB1/ITGAV/NRP1/FBLN1/P4HB/CALR 11 GO:0045862 positive regulation of proteolysis 24/566 372/18722 0.000432864331793359 0.00954015844130711 FN1/RPS3/APOE/HMGB1/ENO1/CYCS/LGMN/SUMO2/DDA1/HSPD1/BAG2/GRN/GABARAP/HSPE1/PDCD5/CDC20/PSMD14/PSMC4/APP/CTSD/FBLN1/PDCD2/UBE2V2/TMEM259 24 GO:0071322 cellular response to carbohydrate stimulus 14/566 163/18722 0.000442188260308319 0.00969764598469279 LGALS1/DYNLL1/HLA-DRB1/LRP1/CYBA/NME1/PHPT1/COLEC12/SERPINF1/LRP5/SRI/PIH1D1/NME2/IGF1R 14 GO:0034502 protein localization to chromosome 10/566 92/18722 0.000459365142897654 0.0100249687067664 CCT8/CCT5/CCT6A/CDK1/BUB3/CCT7/CCT3/TCP1/CCT2/PIH1D1 10 GO:0042769 DNA damage response, detection of DNA damage 4/566 13/18722 0.000475379921243659 0.0103238605335452 RPS3/DNAJA1/MRPS26/MRPS35 4 GO:0051972 regulation of telomerase activity 7/566 47/18722 0.000489536701714177 0.0105796960972404 HSP90AB1/PKIB/PTGES3/TCP1/HNRNPD/CCT2/HNRNPA2B1 7 GO:0014812 muscle cell migration 11/566 110/18722 0.000499668485600728 0.0107247106166474 ANXA1/LRP1/GSTP1/PLXNA1/SEMA6D/ARPC5/NRP1/AIF1/IQGAP1/SERPINE1/P2RY6 11 GO:1901796 regulation of signal transduction by p53 class mediator 10/566 93/18722 0.000501064646959266 0.0107247106166474 NPM1/CD74/RPL26/RPL5/RPL23/MIF/RPS20/RPL11/EEF1E1/TRIAP1 10 GO:0010975 regulation of neuron projection development 27/566 445/18722 0.000509262370733197 0.0108460251838506 FN1/APOE/SPP1/LGALS1/VIM/LRP1/PTPRF/NME1/B2M/ITGA6/PLXNA1/SEMA6D/SEMA3F/CFL1/PLXNB1/TENM3/NRP1/GRN/CDC20/SERPINF1/IQGAP1/MACF1/PLXNB2/NME2/P3H1/UBE2V2/SEMA6A 27 GO:0042060 wound healing 26/566 422/18722 0.000511604961502386 0.0108460251838506 FN1/APOE/F5/HMGB1/ACTG1/FCER1G/ANXA1/PPIA/IL6ST/SERPINE2/EGFR/SPARC/ANXA5/GPX1/MYL12A/ITGB1/B4GALT1/DAG1/PDCD10/LMAN1/PLPP3/MACF1/FBLN1/HBB/GJA1/SERPINE1 26 GO:0006979 response to oxidative stress 27/566 446/18722 0.000527066875396994 0.0111208612761489 LDHA/RPS3/APOE/ANXA1/PRDX1/PPIA/GSTP1/HNRNPM/EGFR/PRDX3/CDK1/GPX1/PARK7/HBA2/TXN/HSPD1/MET/CHCHD2/PDCD10/BNIP3/APP/AIF1/HBB/NUDT15/NME2/P4HB/TXNIP 27 GO:0051131 chaperone-mediated protein complex assembly 5/566 23/18722 0.000531252413197824 0.0111563006771543 HSP90AB1/PTGES3/PSMG1/CCT2/HSPD1 5 GO:0071241 cellular response to inorganic substance 17/566 226/18722 0.000538202859694567 0.0112491977998132 AOC1/CDH1/CCNB1/EGFR/CACYBP/LGMN/B2M/EIF4A3/MT2A/HNRNPD/RAD51/CCNA2/BNIP3/APP/SERPINF1/IQGAP1/CALR 17 GO:0034504 protein localization to nucleus 20/566 290/18722 0.000556438109450037 0.011575992819026 NPM1/RPL23/RAN/HSP90AB1/NUTF2/RPL11/CDH1/CCT8/CCT5/CCT6A/CDK1/PARK7/CCT7/CCT3/TXN/TCP1/CCT2/TXNIP/TFRC/CALR 20 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 6/566 35/18722 0.000571710672111774 0.0118383995918215 HSP90AB1/EIF3H/RPL11/PARK7/PBK/UBXN1 6 GO:0010631 epithelial cell migration 23/566 357/18722 0.000576802886029697 0.0118885483731677 PFN1/APOE/HMGB1/ANXA1/ATP2B4/FSTL1/SPARC/LGMN/GPX1/RAB25/ANXA3/S100P/MET/TMSB4X/NRP1/ITGB1/GRN/PDCD10/SERPINF1/DPP4/PLPP3/MACF1/CALR 23 GO:0007044 cell-substrate junction assembly 10/566 95/18722 0.000593907454265532 0.0121846819649316 FN1/ACTG1/LRP1/LAMC1/ITGA6/S100A10/NRP1/ITGB4/IQGAP1/MACF1 10 GO:0090132 epithelium migration 23/566 360/18722 0.00064693621307213 0.0132117432137483 PFN1/APOE/HMGB1/ANXA1/ATP2B4/FSTL1/SPARC/LGMN/GPX1/RAB25/ANXA3/S100P/MET/TMSB4X/NRP1/ITGB1/GRN/PDCD10/SERPINF1/DPP4/PLPP3/MACF1/CALR 23 GO:0032928 regulation of superoxide anion generation 5/566 24/18722 0.000654511828351221 0.0133054185379892 TYROBP/CYBA/GSTP1/EGFR/GNAI3 5 GO:0032507 maintenance of protein location in cell 8/566 64/18722 0.000662806128287061 0.013352094493819 SRGN/TMSB10/PARK7/TXN/TMSB4X/VPS13C/SCIN/GJA1 8 GO:1903051 negative regulation of proteolysis involved in cellular protein catabolic process 8/566 64/18722 0.000662806128287061 0.013352094493819 RPL5/RPL23/HSP90AB1/EIF3H/RPL11/PARK7/PBK/UBXN1 8 GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage 6/566 36/18722 0.000668734830554292 0.0134108444397645 TPT1/RPS3/CD74/RPL26/MIF/TRIAP1 6 GO:0009566 fertilization 15/566 190/18722 0.000683147540430105 0.0136029218182989 ALDOA/VDAC2/YBX3/CCT8/CCT5/CDK1/PARK7/CCT7/CCT3/TCP1/CCT2/B4GALT1/CD46/HEXB/FOLR1 15 GO:0071333 cellular response to glucose stimulus 13/566 151/18722 0.00068442373928548 0.0136029218182989 LGALS1/DYNLL1/HLA-DRB1/LRP1/CYBA/NME1/PHPT1/SERPINF1/LRP5/SRI/PIH1D1/NME2/IGF1R 13 GO:0010951 negative regulation of endopeptidase activity 18/566 252/18722 0.000689401149269909 0.0136409507402206 GAPDH/CRIM1/SERPINE2/SERPINB1/PRDX3/BIRC5/GPX1/PARK7/TRIAP1/SPINT1/PTTG1/APLP2/ITIH5/APP/SERPINF1/TIMP3/PIH1D1/SERPINE1 18 GO:0014909 smooth muscle cell migration 10/566 97/18722 0.000700534120814612 0.013799902238348 LRP1/GSTP1/PLXNA1/SEMA6D/ARPC5/NRP1/AIF1/IQGAP1/SERPINE1/P2RY6 10 GO:0098754 detoxification 13/566 152/18722 0.000728282804162809 0.0142833261856072 APOE/PRDX1/GSTP1/PRDX3/GPX1/PARK7/HBA2/MT2A/TXN/GSTO1/GLRX/HBB/ESD 13 GO:0009749 response to glucose 16/566 212/18722 0.000748682505184849 0.0146190110222936 LDHA/LGALS1/DYNLL1/HLA-DRB1/LRP1/CYBA/NME1/PHPT1/SERPINF1/LRP5/SRI/GJA1/PIH1D1/NME2/IGF1R/TXNIP 16 GO:0071331 cellular response to hexose stimulus 13/566 153/18722 0.000774483178548537 0.0150398328583861 LGALS1/DYNLL1/HLA-DRB1/LRP1/CYBA/NME1/PHPT1/SERPINF1/LRP5/SRI/PIH1D1/NME2/IGF1R 13 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 6/566 37/18722 0.000778031347618036 0.0150398328583861 EIF3E/MAGOH/RBM8A/EIF4A3/MAGOHB/SMG1 6 GO:0090130 tissue migration 23/566 365/18722 0.000780368686048337 0.0150398328583861 PFN1/APOE/HMGB1/ANXA1/ATP2B4/FSTL1/SPARC/LGMN/GPX1/RAB25/ANXA3/S100P/MET/TMSB4X/NRP1/ITGB1/GRN/PDCD10/SERPINF1/DPP4/PLPP3/MACF1/CALR 23 GO:0046039 GTP metabolic process 5/566 25/18722 0.000797985312957311 0.0152473416879225 RAN/NME1/IMPDH2/GNAI3/NME2 5 GO:1901798 positive regulation of signal transduction by p53 class mediator 5/566 25/18722 0.000797985312957311 0.0152473416879225 RPL26/RPL23/RPS20/RPL11/EEF1E1 5 GO:0009205 purine ribonucleoside triphosphate metabolic process 9/566 82/18722 0.000815638700680662 0.0154578857553347 RAN/ALDOA/ENO1/NME1/IMPDH2/TMSB4X/STOML2/GNAI3/NME2 9 GO:0050922 negative regulation of chemotaxis 8/566 66/18722 0.000815948596698936 0.0154578857553347 MIF/GSTP1/SEMA6D/SEMA3F/NRP1/AIF1/DPP4/SEMA6A 8 GO:0071326 cellular response to monosaccharide stimulus 13/566 154/18722 0.000823122518184137 0.0155277180125245 LGALS1/DYNLL1/HLA-DRB1/LRP1/CYBA/NME1/PHPT1/SERPINF1/LRP5/SRI/PIH1D1/NME2/IGF1R 13 GO:1901654 response to ketone 15/566 194/18722 0.000846616449838722 0.0159035292602616 SPP1/CALM1/TYMS/CYBA/NME1/EGFR/RPL27/PARK7/HNRNPD/SERPINF1/ATP2B1/GLB1/TXNIP/P2RY6/CALR 15 GO:0048569 post-embryonic animal organ development 4/566 15/18722 0.000864875707860746 0.0160434443808168 LDHA/FBN1/HMGN1/EFEMP1 4 GO:0098760 response to interleukin-7 4/566 15/18722 0.000864875707860746 0.0160434443808168 YBX1/HMGB1/HSPD1/P4HB 4 GO:0098761 cellular response to interleukin-7 4/566 15/18722 0.000864875707860746 0.0160434443808168 YBX1/HMGB1/HSPD1/P4HB 4 GO:0031103 axon regeneration 7/566 52/18722 0.000914385031023145 0.0168914612369919 SPP1/LRP1/PTPRF/ISL1/GRN/DAG1/FOLR1 7 GO:0050684 regulation of mRNA processing 12/566 137/18722 0.00093442699334272 0.017190367662652 NPM1/SRSF3/HNRNPA1/SRSF7/NCL/SRSF9/CCNB1/MAGOH/RBM8A/CIRBP/DAZAP1/RBM23 12 GO:0150115 cell-substrate junction organization 10/566 101/18722 0.000961317536268623 0.0176122867138597 FN1/ACTG1/LRP1/LAMC1/ITGA6/S100A10/NRP1/ITGB4/IQGAP1/MACF1 10 GO:0006405 RNA export from nucleus 9/566 84/18722 0.00097155160067292 0.0177268349434256 NPM1/SRSF3/HNRNPA1/RAN/ALYREF/SSB/HNRNPA2B1/THOC6/SMG1 9 GO:0007566 embryo implantation 7/566 53/18722 0.00102652549617442 0.0186534347304838 SPP1/RPL29/ITGB4/PRLR/FBLN1/GJA1/CALR 7 GO:0051897 positive regulation of protein kinase B signaling 11/566 120/18722 0.00103831385228123 0.0187909482534798 LRP2/HSP90AB1/EGFR/GPX1/PARK7/TXN/MET/ITGB1/ENG/IGF2/IGF1R 11 GO:2001020 regulation of response to DNA damage stimulus 16/566 219/18722 0.0010579984454439 0.0189947035179299 TPT1/NPM1/RPS3/CD74/RPL26/MIF/HMGB1/EEF1E1/UBE2N/EGFR/DEK/TRIAP1/RAD51/PPP4C/UBE2V2/SMG1 16 GO:0032092 positive regulation of protein binding 9/566 85/18722 0.00105810567665018 0.0189947035179299 APOE/RAN/HSP90AB1/LRP1/RPL11/B2M/AMFR/NRP1/APP 9 GO:0022409 positive regulation of cell-cell adhesion 19/566 284/18722 0.00108716872231447 0.0194380528182491 RPS3/CD74/LGALS1/HMGB1/HLA-DRB1/HLA-DPA1/HLA-A/ANXA1/HLA-DRA/HLA-DPB1/IL6ST/B2M/HSPD1/CD46/AIF1/DPP4/IGF2/PLPP3/TFRC 19 GO:0001732 formation of cytoplasmic translation initiation complex 4/566 16/18722 0.00112577647419996 0.0199679556300328 EIF3E/EIF3H/EIF2S2/EIF3I 4 GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 4/566 16/18722 0.00112577647419996 0.0199679556300328 CD74/RPL26/MIF/TRIAP1 4 GO:1901361 organic cyclic compound catabolic process 28/566 495/18722 0.00118778349812527 0.0209841751335464 NPM1/APOE/SPP1/YBX1/VIM/EIF3E/YBX3/LSM6/HNRNPM/HNRNPC/MAGOH/SSB/LSM4/RBM8A/EIF4A3/DUT/LSM5/HNRNPD/CIRBP/RNASEH2A/STS/MTHFS/MAGOHB/DNPH1/NUDT15/ZCCHC17/SMG1/EXOSC9 28 GO:0044772 mitotic cell cycle phase transition 25/566 424/18722 0.0012118412250738 0.0212406186379078 RPS6/RPL26/CALM1/ANXA1/RPL24/MAD2L1/CCNB1/EGFR/CDK1/CCNE1/BUB3/TRIAP1/CDK2AP2/ITGB1/CKS2/ZWINT/CCNB2/UBE2S/CCNA2/ANAPC11/APP/AIF1/GPNMB/CDC26/DBF4 25 GO:0048608 reproductive structure development 25/566 424/18722 0.0012118412250738 0.0212406186379078 KRT19/RPS6/LRP2/SPP1/HMGB2/HSP90AB1/YBX3/ANXA1/SERPINE2/PSAP/PRDX3/ADGRG1/CGA/KRT8/SPINT1/ITGB8/EIF2S2/SERPINF1/DAZAP1/IGF2/MEA1/GJA1/MME/HTRA1/CTSB 25 GO:0019646 aerobic electron transport chain 9/566 87/18722 0.00124994017471029 0.0217372408508211 UQCRH/CYCS/COX4I1/PARK7/NDUFB3/COX7A2L/NDUFA10/COX5A/NDUFS3 9 GO:0150104 transport across blood-brain barrier 9/566 87/18722 0.00124994017471029 0.0217372408508211 LRP2/APOE/ATP2B4/LRP1/SLC2A1/SLC19A1/SLC38A2/TFRC/SLC1A5 9 GO:1903311 regulation of mRNA metabolic process 19/566 288/18722 0.00128028791469988 0.0221783727480305 NPM1/SRSF3/YBX1/HNRNPA1/VIM/YBX3/SRSF7/NCL/HNRNPM/HNRNPC/SRSF9/CCNB1/MAGOH/RBM8A/HNRNPD/CIRBP/DAZAP1/RBM23/EXOSC9 19 GO:0034250 positive regulation of cellular amide metabolic process 13/566 162/18722 0.00131266950319907 0.0226511807296211 NPM1/RPL26/RPL5/RPS4X/VIM/EIF3E/YBX3/PKM/EIF4A3/HNRNPD/CIRBP/RPS9/PLXNB2 13 GO:0061458 reproductive system development 25/566 427/18722 0.00133590939942992 0.0229631994064171 KRT19/RPS6/LRP2/SPP1/HMGB2/HSP90AB1/YBX3/ANXA1/SERPINE2/PSAP/PRDX3/ADGRG1/CGA/KRT8/SPINT1/ITGB8/EIF2S2/SERPINF1/DAZAP1/IGF2/MEA1/GJA1/MME/HTRA1/CTSB 25 GO:0071634 regulation of transforming growth factor beta production 6/566 41/18722 0.00135880994068287 0.0232670071381544 FN1/HSP90AB1/TYROBP/ITGB8/ITGAV/CD46 6 GO:0050678 regulation of epithelial cell proliferation 23/566 381/18722 0.0013801229487666 0.0235414075398809 APOE/HMGB2/HMGB1/FLT1/LAMC1/CYBA/HMGN1/NME1/EGFR/ISL1/SPARC/GPX1/B2M/LAMB1/NRP1/B4GALT1/GRN/PDCD10/SERPINF1/IGF2/GJA1/NME2/HTRA1 23 GO:0050769 positive regulation of neurogenesis 16/566 225/18722 0.00140344790210553 0.0238479009930298 FN1/LRP2/LRP1/IL6ST/SERPINE2/EGFR/PLXNA1/SPINT1/PLXNB1/NRP1/DAG1/SERPINF1/MACF1/PLXNB2/MME/FAIM 16 GO:0043388 positive regulation of DNA binding 7/566 56/18722 0.00142883021189145 0.0240727842516665 HMGB2/HMGB1/CALM1/NME1/ISL1/PARK7/TXN 7 GO:0071385 cellular response to glucocorticoid stimulus 7/566 56/18722 0.00142883021189145 0.0240727842516665 ANXA1/UBE2L3/GSTP1/EGFR/ISL1/SERPINF1/ATP2B1 7 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 4/566 17/18722 0.00143723777444645 0.0240727842516665 HLA-B/HLA-C/HLA-A/B2M 4 GO:0071900 regulation of protein serine/threonine kinase activity 22/566 359/18722 0.00143831100874737 0.0240727842516665 RPS3/APOE/CALM1/FLT1/HSP90AB1/ATP2B4/DNAJA1/CKS1B/GSTP1/PKIB/CCNB1/EGFR/CCNE1/CKS2/PDCD10/CCNB2/CCNA2/IGF2/LRP5/IQGAP1/PIH1D1/DBF4 22 GO:0033627 cell adhesion mediated by integrin 8/566 72/18722 0.0014521694914663 0.0241233528955521 FBN1/ITGB8/ITGAV/ITGB1/ITGB4/DPP4/PLPP3/SERPINE1 8 GO:1903036 positive regulation of response to wounding 8/566 72/18722 0.0014521694914663 0.0241233528955521 HMGB1/ACTG1/ANXA1/LRP1/ITGB1/GRN/PLPP3/SERPINE1 8 GO:2000058 regulation of ubiquitin-dependent protein catabolic process 13/566 164/18722 0.00146712171667486 0.0241309715008496 RPL5/RPL23/HSP90AB1/EIF3H/RPL11/SUMO2/PARK7/DDA1/PBK/GABARAP/UBXN1/CDC20/UBE2V2 13 GO:0009199 ribonucleoside triphosphate metabolic process 9/566 89/18722 0.00146888887617481 0.0241309715008496 RAN/ALDOA/ENO1/NME1/IMPDH2/TMSB4X/STOML2/GNAI3/NME2 9 GO:0014910 regulation of smooth muscle cell migration 9/566 89/18722 0.00146888887617481 0.0241309715008496 LRP1/GSTP1/PLXNA1/SEMA6D/NRP1/AIF1/IQGAP1/SERPINE1/P2RY6 9 GO:0007229 integrin-mediated signaling pathway 10/566 107/18722 0.00149717707751514 0.0245052659893287 FN1/LAMA5/ITGA6/ITGB8/ITGAV/NRP1/ITGB1/ITGB4/PLPP3/NME2 10 GO:0034655 nucleobase-containing compound catabolic process 24/566 407/18722 0.00150372170161196 0.0245222308262873 NPM1/YBX1/VIM/EIF3E/YBX3/LSM6/HNRNPM/HNRNPC/MAGOH/SSB/LSM4/RBM8A/EIF4A3/DUT/LSM5/HNRNPD/CIRBP/RNASEH2A/MAGOHB/DNPH1/NUDT15/ZCCHC17/SMG1/EXOSC9 24 GO:0009124 nucleoside monophosphate biosynthetic process 6/566 42/18722 0.00154540670166131 0.0251100388167742 TYMS/DUT/IMPDH2/TK1/UMPS/GMPS 6 GO:0032392 DNA geometric change 9/566 90/18722 0.00158936870231513 0.0257304344098434 HMGB2/HMGB1/ANXA1/HMGB3/RFC2/HNRNPA2B1/RFC3/RAD51/RUVBL1 9 GO:0033138 positive regulation of peptidyl-serine phosphorylation 10/566 108/18722 0.00160639956302948 0.0257639734010012 MIF/HSP90AB1/ATP2B4/EGFR/PARK7/TXN/PDCD10/AKAP9/APP/TFRC 10 GO:0001916 positive regulation of T cell mediated cytotoxicity 5/566 29/18722 0.00161458862957757 0.0257639734010012 HLA-B/HLA-DRB1/HLA-A/HLA-DRA/B2M 5 GO:0070979 protein K11-linked ubiquitination 5/566 29/18722 0.00161458862957757 0.0257639734010012 UBE2L3/UBE2T/UBE2S/ANAPC11/CDC26 5 GO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator 5/566 29/18722 0.00161458862957757 0.0257639734010012 CD74/RPL26/MIF/RPL11/TRIAP1 5 GO:0051962 positive regulation of nervous system development 18/566 272/18722 0.00164166256908404 0.0261024348484363 FN1/LRP2/LRP1/IL6ST/SERPINE2/EGFR/PLXNA1/SPINT1/PLXNB1/NRP1/DAG1/CLSTN1/SERPINF1/MACF1/PLXNB2/MME/FAIM/UBE2V2 18 GO:0031589 cell-substrate adhesion 22/566 363/18722 0.00165392534445886 0.026203827877334 FN1/LGALS1/LAMA5/ACTG1/LRP1/LAMC1/BCAM/ITGA6/S100A10/ARPC2/LAMB1/ITGAV/NRP1/ITGB1/DAG1/ITGB4/IQGAP1/MACF1/FBLN1/SERPINE1/P4HB/CALR 22 GO:0050767 regulation of neurogenesis 22/566 364/18722 0.00171194906140147 0.0270269405012743 FN1/LRP2/SPP1/HMGB2/LRP1/IL6ST/SERPINE2/EGFR/B2M/PLXNA1/SEMA6D/SEMA3F/SPINT1/PLXNB1/NRP1/DAG1/SERPINF1/MACF1/PLXNB2/MME/FAIM/SEMA6A 22 GO:1903034 regulation of response to wounding 13/566 167/18722 0.0017268664473388 0.0271661110372874 APOE/SPP1/HMGB1/ACTG1/ANXA1/LRP1/SERPINE2/PTPRF/ITGB1/GRN/PLPP3/GJA1/SERPINE1 13 GO:0006458 'de novo' protein folding 6/566 43/18722 0.00175086940056609 0.0272547922074134 CD74/PTGES3/HSPA9/CCT2/HSPD1/HSPE1 6 GO:0071604 transforming growth factor beta production 6/566 43/18722 0.00175086940056609 0.0272547922074134 FN1/HSP90AB1/TYROBP/ITGB8/ITGAV/CD46 6 GO:1904591 positive regulation of protein import 6/566 43/18722 0.00175086940056609 0.0272547922074134 RAN/HSP90AB1/NUTF2/CDH1/CDK1/PDCD5 6 GO:0048732 gland development 25/566 436/18722 0.00177598918389542 0.0275494907550607 RPS16/LAMA5/ANXA1/TYMS/CDH1/SERPINE2/PSAP/NME1/EGFR/ISL1/RPL19/GPX1/PLXNA1/CGA/HNRNPD/MET/UMPS/NRP1/DAG1/CCNB2/KRT18/SERPINF1/IGF2/LRP5/PRLR 25 GO:0050673 epithelial cell proliferation 25/566 437/18722 0.0018318031576594 0.0283166238121516 APOE/HMGB2/HMGB1/FLT1/LAMC1/CYBA/SERPINB1/HMGN1/NME1/EGFR/ISL1/LGR5/SPARC/GPX1/B2M/LAMB1/NRP1/B4GALT1/GRN/PDCD10/SERPINF1/IGF2/GJA1/NME2/HTRA1 25 GO:0006221 pyrimidine nucleotide biosynthetic process 5/566 30/18722 0.00188996358734703 0.0290443609239182 TYMS/NME1/DUT/UMPS/NME2 5 GO:1903363 negative regulation of cellular protein catabolic process 8/566 75/18722 0.00189192827222288 0.0290443609239182 RPL5/RPL23/HSP90AB1/EIF3H/RPL11/PARK7/PBK/UBXN1 8 GO:0040013 negative regulation of locomotion 23/566 391/18722 0.00192840997737486 0.0295026846023122 CD74/MIF/APOE/HMGB1/ATP2B4/LRP1/CDH1/GSTP1/ADGRG1/SEMA6D/SEMA3F/NRP1/ENG/DAG1/PDCD10/AIF1/SERPINF1/DPP4/FBLN1/GJA1/SERPINE1/SEMA6A/CALR 23 GO:0000280 nuclear division 25/566 439/18722 0.00194795157399243 0.0296995904363504 RANBP1/RAN/RPL24/MAD2L1/CCNB1/NUDC/CCNE1/BUB3/CHMP5/CENPK/PTTG1/CKS2/RAD51/ZWINT/MND1/CCNB2/UBE2S/CDC20/ANAPC11/IGF2/CCNB1IP1/LRP5/CDC26/MKI67/CALR 25 GO:0043467 regulation of generation of precursor metabolites and energy 11/566 130/18722 0.00198581063523263 0.0301734776384152 HMGB1/CCNB1/CDK1/PPP1CA/PARK7/GHITM/COX7A2L/CHCHD2/BNIP3/APP/IGF2 11 GO:0031100 animal organ regeneration 8/566 76/18722 0.00205977734700863 0.0310851821996014 RPS16/TYMS/GSTP1/EGFR/CDK1/RPL19/ANXA3/CCNA2 8 GO:0071426 ribonucleoprotein complex export from nucleus 8/566 76/18722 0.00205977734700863 0.0310851821996014 NPM1/SRSF3/RAN/ALYREF/SSB/HNRNPA2B1/THOC6/SMG1 8 GO:0048640 negative regulation of developmental growth 10/566 112/18722 0.0021097164120175 0.0315968215209073 SPP1/LGMN/SLC6A4/SEMA6D/SEMA3F/CGA/NRP1/GJA1/ADRB1/SEMA6A 10 GO:0046683 response to organophosphorus 11/566 131/18722 0.00211030405170364 0.0315968215209073 LDHA/TYMS/NME1/SPARC/SLC6A4/HSPD1/RFC3/AKAP9/APP/HSP90B1/P2RY6 11 GO:0006913 nucleocytoplasmic transport 19/566 301/18722 0.00212206865111215 0.0315968215209073 NPM1/RPL23/SRSF3/HNRNPA1/RAN/HSP90AB1/NUTF2/CDH1/ALYREF/SSB/CDK1/PARK7/TXN/HSPA9/HNRNPA2B1/THOC6/SMG1/TXNIP/CALR 19 GO:0051169 nuclear transport 19/566 301/18722 0.00212206865111215 0.0315968215209073 NPM1/RPL23/SRSF3/HNRNPA1/RAN/HSP90AB1/NUTF2/CDH1/ALYREF/SSB/CDK1/PARK7/TXN/HSPA9/HNRNPA2B1/THOC6/SMG1/TXNIP/CALR 19 GO:0042129 regulation of T cell proliferation 13/566 171/18722 0.00213128593557689 0.0316282832839611 RPS3/HMGB1/HLA-DRB1/HLA-DPA1/HLA-A/ANXA1/HLA-DPB1/IL6ST/CD46/AIF1/GPNMB/IGF2/TFRC 13 GO:0031102 neuron projection regeneration 7/566 60/18722 0.00214527397247571 0.0317300987556872 SPP1/LRP1/PTPRF/ISL1/GRN/DAG1/FOLR1 7 GO:0051443 positive regulation of ubiquitin-protein transferase activity 5/566 31/18722 0.00219816763346207 0.03229782938671 RPS2/UBE2L3/UBE2N/UBE2S/CDC20 5 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors 5/566 31/18722 0.00219816763346207 0.03229782938671 HMGB2/GPX1/PARK7/SERPINE1/FAIM 5 GO:0045780 positive regulation of bone resorption 4/566 19/18722 0.0022310582406041 0.0326438882808181 SPP1/EGFR/ATP6AP1/TFRC 4 GO:0071166 ribonucleoprotein complex localization 8/566 77/18722 0.00223912195440708 0.0326438882808181 NPM1/SRSF3/RAN/ALYREF/SSB/HNRNPA2B1/THOC6/SMG1 8 GO:0001678 cellular glucose homeostasis 13/566 172/18722 0.00224371738857375 0.0326438882808181 LGALS1/DYNLL1/HLA-DRB1/LRP1/CYBA/NME1/PHPT1/SERPINF1/LRP5/SRI/PIH1D1/NME2/IGF1R 13 GO:0046700 heterocycle catabolic process 25/566 445/18722 0.00233493959640442 0.0338604269810829 NPM1/YBX1/VIM/EIF3E/YBX3/LSM6/HNRNPM/HNRNPC/MAGOH/SSB/LSM4/RBM8A/EIF4A3/DUT/LSM5/HNRNPD/CIRBP/RNASEH2A/MTHFS/MAGOHB/DNPH1/NUDT15/ZCCHC17/SMG1/EXOSC9 25 GO:0071384 cellular response to corticosteroid stimulus 7/566 61/18722 0.00236149579688616 0.034134348336809 ANXA1/UBE2L3/GSTP1/EGFR/ISL1/SERPINF1/ATP2B1 7 GO:0010595 positive regulation of endothelial cell migration 11/566 133/18722 0.00237831512871391 0.0342662102039946 HMGB1/ANXA1/SPARC/LGMN/ANXA3/MET/TMSB4X/NRP1/GRN/PLPP3/CALR 11 GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 11/566 134/18722 0.00252229547422415 0.0360997941236462 HSP90AB1/EIF3H/RPL11/SUMO2/PARK7/DDA1/PBK/GABARAP/UBXN1/CDC20/UBE2V2 11 GO:0035767 endothelial cell chemotaxis 5/566 32/18722 0.00254141050939173 0.0360997941236462 HMGB1/LGMN/MET/TMSB4X/NRP1 5 GO:0042744 hydrogen peroxide catabolic process 5/566 32/18722 0.00254141050939173 0.0360997941236462 PRDX1/PRDX3/GPX1/HBA2/HBB 5 GO:0072337 modified amino acid transport 5/566 32/18722 0.00254141050939173 0.0360997941236462 LRP2/SLC19A1/SLC38A2/GJA1/FOLR1 5 GO:0050863 regulation of T cell activation 20/566 329/18722 0.0025461220473551 0.0360997941236462 RPS3/CD74/LGALS1/HMGB1/HLA-DRB1/HLA-DPA1/HLA-A/ANXA1/HLA-DRA/HLA-DPB1/IL6ST/B2M/HSPD1/CD46/AIF1/DPP4/GPNMB/IGF2/TFRC/CLPTM1 20 GO:0043393 regulation of protein binding 14/566 196/18722 0.00261484232948995 0.0369564382567913 APOE/RAN/HSP90AB1/LRP1/RPL11/PTPRF/PPP1CA/B2M/PARK7/AMFR/BAG2/NRP1/APP/GTF2F1 14 GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 9/566 97/18722 0.00267180869057032 0.0376420642101869 HMGB2/GSTP1/GPX1/PARK7/ITGA6/ITGAV/NRP1/SERPINE1/FAIM 9 GO:0010952 positive regulation of peptidase activity 14/566 197/18722 0.00273914999540588 0.0383095191266792 FN1/RPS3/HMGB1/CYCS/LGMN/HSPD1/GRN/HSPE1/PDCD5/PSMD14/APP/CTSD/FBLN1/PDCD2 14 GO:0010634 positive regulation of epithelial cell migration 13/566 176/18722 0.00274329190904801 0.0383095191266792 PFN1/HMGB1/ANXA1/SPARC/LGMN/RAB25/ANXA3/MET/TMSB4X/NRP1/GRN/PLPP3/CALR 13 GO:0044270 cellular nitrogen compound catabolic process 25/566 451/18722 0.00278559967322164 0.0383095191266792 NPM1/YBX1/VIM/EIF3E/YBX3/LSM6/HNRNPM/HNRNPC/MAGOH/SSB/LSM4/RBM8A/EIF4A3/DUT/LSM5/HNRNPD/CIRBP/RNASEH2A/MTHFS/MAGOHB/DNPH1/NUDT15/ZCCHC17/SMG1/EXOSC9 25 GO:0014911 positive regulation of smooth muscle cell migration 6/566 47/18722 0.00278567013060271 0.0383095191266792 LRP1/SEMA6D/NRP1/AIF1/IQGAP1/P2RY6 6 GO:0032070 regulation of deoxyribonuclease activity 3/566 10/18722 0.00281381140065581 0.0383095191266792 NPM1/RPS3/HMGB1 3 GO:0036363 transforming growth factor beta activation 3/566 10/18722 0.00281381140065581 0.0383095191266792 HSP90AB1/ITGB8/ITGAV 3 GO:0042989 sequestering of actin monomers 3/566 10/18722 0.00281381140065581 0.0383095191266792 TMSB10/TMSB4X/SCIN 3 GO:0061299 retina vasculature morphogenesis in camera-type eye 3/566 10/18722 0.00281381140065581 0.0383095191266792 COL4A1/NRP1/LRP5 3 GO:1901524 regulation of mitophagy 3/566 10/18722 0.00281381140065581 0.0383095191266792 VDAC1/SLC25A5/VPS13C 3 GO:0050878 regulation of body fluid levels 22/566 379/18722 0.00281383934286256 0.0383095191266792 FN1/APOE/F5/ACTG1/FCER1G/PPIA/IL6ST/CYBA/SERPINE2/STMN1/NME1/EGFR/ANXA5/MYL12A/MET/UMPS/LMAN1/PRLR/FBLN1/HBB/GJA1/SERPINE1 22 GO:0051346 negative regulation of hydrolase activity 22/566 379/18722 0.00281383934286256 0.0383095191266792 GAPDH/APOC1/CRIM1/ANXA1/LRP1/SERPINE2/SERPINB1/PRDX3/BIRC5/GPX1/PARK7/TRIAP1/SPINT1/PTTG1/UBXN1/APLP2/ITIH5/APP/SERPINF1/TIMP3/PIH1D1/SERPINE1 22 GO:0061337 cardiac conduction 9/566 98/18722 0.00286518952178191 0.0388897065578447 CALM1/ATP2B4/ISL1/AKAP9/DSC2/SRI/GJA1/ATP2B1/DSG2 9 GO:0071353 cellular response to interleukin-4 5/566 33/18722 0.00292191345811778 0.0393001773883394 RPL3/RPLP0/HSP90AB1/TUBA1B/IMPDH2 5 GO:1903146 regulation of autophagy of mitochondrion 5/566 33/18722 0.00292191345811778 0.0393001773883394 VDAC1/SLC25A5/PARK7/BNIP3/VPS13C 5 GO:1904031 positive regulation of cyclin-dependent protein kinase activity 5/566 33/18722 0.00292191345811778 0.0393001773883394 HSP90AB1/CKS1B/CCNB1/EGFR/CKS2 5 GO:0140014 mitotic nuclear division 18/566 287/18722 0.00293936686022371 0.0393779885446168 RANBP1/RAN/RPL24/MAD2L1/CCNB1/NUDC/BUB3/CHMP5/CENPK/PTTG1/ZWINT/UBE2S/CDC20/ANAPC11/IGF2/LRP5/CDC26/MKI67 18 GO:0060326 cell chemotaxis 19/566 310/18722 0.00294538863103265 0.0393779885446168 CD74/MIF/HMGB2/HMGB1/FLT1/CSF3R/FCER1G/ANXA1/PPIA/GSTP1/RPS19/LGMN/MET/TMSB4X/NRP1/AIF1/DPP4/SERPINE1/CALR 19 GO:0042098 T cell proliferation 14/566 199/18722 0.00300235443059375 0.040019406961088 RPS6/RPS3/HMGB1/HLA-DRB1/HLA-DPA1/HLA-A/ANXA1/HLA-DPB1/IL6ST/CD46/AIF1/GPNMB/IGF2/TFRC 14 GO:0097193 intrinsic apoptotic signaling pathway 18/566 288/18722 0.00304997212325865 0.0404791201914643 TPT1/RPS3/CD74/RPL26/MIF/VDAC2/YBX3/ENO1/DNAJA1/PPIA/RPL11/GPX1/PARK7/TRIAP1/PDCD10/BNIP3/NDUFS3/P4HB 18 GO:0010810 regulation of cell-substrate adhesion 15/566 221/18722 0.00305568847841882 0.0404791201914643 FN1/LGALS1/ACTG1/LRP1/ITGA6/S100A10/ARPC2/NRP1/DAG1/IQGAP1/MACF1/FBLN1/SERPINE1/P4HB/CALR 15 GO:0006165 nucleoside diphosphate phosphorylation 9/566 99/18722 0.00306946210005307 0.0404791201914643 GAPDH/LDHA/TPI1/ALDOA/ENO1/PKM/NME1/APP/NME2 9 GO:0014032 neural crest cell development 8/566 81/18722 0.00308230497414789 0.0404791201914643 FN1/LAMA5/ISL1/SEMA6D/SEMA3F/NRP1/FOLR1/SEMA6A 8 GO:0071260 cellular response to mechanical stimulus 8/566 81/18722 0.00308230497414789 0.0404791201914643 CYBA/EGFR/SLC2A1/SLC38A2/ENG/DAG1/BNIP3/GJA1 8 GO:0051101 regulation of DNA binding 10/566 118/18722 0.00309541463201455 0.0405317233580259 HMGB2/HMGB1/CALM1/NME1/ISL1/PARK7/TXN/TMSB4X/ZNF593/SRI 10 GO:0071902 positive regulation of protein serine/threonine kinase activity 14/566 200/18722 0.0031415305816569 0.0410149388549458 RPS3/CALM1/FLT1/HSP90AB1/ATP2B4/CKS1B/CCNB1/EGFR/CKS2/PDCD10/IGF2/IQGAP1/PIH1D1/DBF4 14 GO:0045787 positive regulation of cell cycle 19/566 313/18722 0.00327315817094606 0.0421344953334579 NPM1/RANBP1/ANXA1/CKS1B/MAD2L1/CCNB1/EGFR/CDK1/LGMN/SLC6A4/RPS15A/CKS2/ANAPC11/APP/AIF1/IGF2/LRP5/DBF4/CALR 19 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen 4/566 21/18722 0.00328406780788632 0.0421344953334579 CYCS/COX4I1/COX7A2L/COX5A 4 GO:0031145 anaphase-promoting complex-dependent catabolic process 4/566 21/18722 0.00328406780788632 0.0421344953334579 UBE2S/CDC20/ANAPC11/CDC26 4 GO:0046514 ceramide catabolic process 4/566 21/18722 0.00328406780788632 0.0421344953334579 HEXB/ASAH1/HEXA/GM2A 4 GO:0060445 branching involved in salivary gland morphogenesis 4/566 21/18722 0.00328406780788632 0.0421344953334579 LAMA5/PLXNA1/NRP1/DAG1 4 GO:0090026 positive regulation of monocyte chemotaxis 4/566 21/18722 0.00328406780788632 0.0421344953334579 HMGB1/LGMN/AIF1/SERPINE1 4 GO:0050920 regulation of chemotaxis 15/566 223/18722 0.00332639149202742 0.0423110139608574 CD74/MIF/HMGB1/GSTP1/LGMN/SEMA6D/SEMA3F/MET/TMSB4X/NRP1/AIF1/DPP4/SERPINE1/SEMA6A/CALR 15 GO:0002183 cytoplasmic translational initiation 5/566 34/18722 0.00334190234333461 0.0423110139608574 RPL13A/EIF3E/EIF3H/EIF2S2/EIF3I 5 GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 5/566 34/18722 0.00334190234333461 0.0423110139608574 NPM1/CD74/RPL26/MIF/EEF1E1 5 GO:0051973 positive regulation of telomerase activity 5/566 34/18722 0.00334190234333461 0.0423110139608574 HSP90AB1/PKIB/PTGES3/TCP1/CCT2 5 GO:0062197 cellular response to chemical stress 20/566 337/18722 0.0033453452188279 0.0423110139608574 RPS3/YBX3/ANXA1/PRDX1/DNAJA1/PPIA/EGFR/SLC2A1/PRDX3/CDK1/GPX1/PARK7/TXN/MET/CHCHD2/PDCD10/BNIP3/AIF1/NME2/P4HB 20 GO:0010965 regulation of mitotic sister chromatid separation 7/566 65/18722 0.00339853212495717 0.042763787178936 MAD2L1/CCNB1/BUB3/PTTG1/ZWINT/ANAPC11/CDC26 7 GO:0006692 prostanoid metabolic process 6/566 49/18722 0.0034483826588585 0.042763787178936 CD74/MIF/ANXA1/GSTP1/PTGES3/HPGD 6 GO:0006693 prostaglandin metabolic process 6/566 49/18722 0.0034483826588585 0.042763787178936 CD74/MIF/ANXA1/GSTP1/PTGES3/HPGD 6 GO:0010823 negative regulation of mitochondrion organization 6/566 49/18722 0.0034483826588585 0.042763787178936 SLC25A5/GPX1/TRIAP1/GHITM/BNIP3/TFRC 6 GO:0052372 modulation by symbiont of entry into host 6/566 49/18722 0.0034483826588585 0.042763787178936 CD74/LGALS1/HLA-DRB1/IFITM2/ITGAV/P4HB 6 GO:1901799 negative regulation of proteasomal protein catabolic process 6/566 49/18722 0.0034483826588585 0.042763787178936 HSP90AB1/EIF3H/RPL11/PARK7/PBK/UBXN1 6 GO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors 6/566 49/18722 0.0034483826588585 0.042763787178936 HMGB2/GPX1/PARK7/TIMP3/SERPINE1/FAIM 6 GO:0048675 axon extension 10/566 120/18722 0.003495249878121 0.0431073228857835 FN1/APOE/HSP90AB1/LRP1/SEMA6D/SEMA3F/NRP1/ITGB1/MACF1/SEMA6A 10 GO:0051251 positive regulation of lymphocyte activation 21/566 362/18722 0.003495450036336 0.0431073228857835 RPS3/CD74/MIF/LGALS1/HMGB1/HLA-DRB1/TYROBP/HLA-DPA1/HLA-A/ANXA1/HLA-DRA/HLA-DPB1/IL6ST/B2M/HSPD1/CD46/AIF1/DPP4/IGF2/SLC39A10/TFRC 21 GO:0046939 nucleotide phosphorylation 9/566 101/18722 0.00351236721439974 0.043196295133999 GAPDH/LDHA/TPI1/ALDOA/ENO1/PKM/NME1/APP/NME2 9 GO:0010632 regulation of epithelial cell migration 18/566 292/18722 0.00352765451595009 0.0432647876171069 PFN1/APOE/HMGB1/ANXA1/ATP2B4/SPARC/LGMN/RAB25/ANXA3/MET/TMSB4X/NRP1/GRN/PDCD10/SERPINF1/PLPP3/MACF1/CALR 18 GO:0007568 aging 20/566 339/18722 0.0035749880777818 0.0437248541821005 NPM1/MIF/YBX1/COL4A2/LRP1/TYMS/EEF1E1/CACYBP/CDK1/B2M/AMFR/DAG1/RSL1D1/APP/SERPINF1/CANX/ATP2B1/MME/SERPINE1/CALR 20 GO:0050918 positive chemotaxis 7/566 66/18722 0.00370494034017425 0.0451901216286459 MIF/HMGB2/HMGB1/LRP1/MET/NRP1/GPNMB 7 GO:0006183 GTP biosynthetic process 3/566 11/18722 0.0037826455912545 0.0455144274926082 NME1/IMPDH2/NME2 3 GO:0033860 regulation of NAD(P)H oxidase activity 3/566 11/18722 0.0037826455912545 0.0455144274926082 CYBA/PARK7/GNAI3 3 GO:0035581 sequestering of extracellular ligand from receptor 3/566 11/18722 0.0037826455912545 0.0455144274926082 FBN2/FBN1/CD46 3 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity 3/566 11/18722 0.0037826455912545 0.0455144274926082 CALM1/GSTO1/SRI 3 GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 3/566 11/18722 0.0037826455912545 0.0455144274926082 CD74/HMGB1/LRP1 3 GO:0001893 maternal placenta development 5/566 35/18722 0.00380360095520507 0.0455205146574543 SPP1/PRDX3/DAZAP1/GJA1/CTSB 5 GO:0072528 pyrimidine-containing compound biosynthetic process 5/566 35/18722 0.00380360095520507 0.0455205146574543 TYMS/NME1/DUT/UMPS/NME2 5 GO:0032069 regulation of nuclease activity 4/566 22/18722 0.0039191317474942 0.0467409429801793 NPM1/RPS3/HMGB2/HMGB1 4 GO:0048285 organelle fission 26/566 488/18722 0.00392657517398631 0.0467409429801793 RANBP1/RAN/RPL24/MAD2L1/CCNB1/NUDC/CCNE1/BUB3/CHMP5/CENPK/PTTG1/CKS2/RAD51/ZWINT/MND1/CCNB2/UBE2S/CDC20/BNIP3/ANAPC11/IGF2/CCNB1IP1/LRP5/CDC26/MKI67/CALR 26 GO:0007051 spindle organization 13/566 184/18722 0.00401564645733441 0.0473975091315195 RPS3/RAN/STMN1/SPC25/CCNB1/NUDC/HAUS1/CHMP5/CCNB2/CDC20/HAUS8/CENPH/TUBGCP2 13 GO:0051306 mitotic sister chromatid separation 7/566 67/18722 0.00403189019104592 0.0473975091315195 MAD2L1/CCNB1/BUB3/PTTG1/ZWINT/ANAPC11/CDC26 7 GO:0061077 chaperone-mediated protein folding 7/566 67/18722 0.00403189019104592 0.0473975091315195 CD74/PTGES3/HSPA9/CCT2/HSPE1/PDCD5/P3H1 7 GO:0070527 platelet aggregation 7/566 67/18722 0.00403189019104592 0.0473975091315195 FN1/ACTG1/PPIA/IL6ST/SERPINE2/MYL12A/HBB 7 GO:0010976 positive regulation of neuron projection development 12/566 163/18722 0.00403496315382882 0.0473975091315195 APOE/LRP1/NME1/ITGA6/TENM3/GRN/SERPINF1/IQGAP1/PLXNB2/NME2/P3H1/UBE2V2 12 GO:0009142 nucleoside triphosphate biosynthetic process 8/566 85/18722 0.00415395597599991 0.0486668736977673 ALDOA/ENO1/TYMS/NME1/IMPDH2/TMSB4X/STOML2/NME2 8 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus 5/566 36/18722 0.00430922452369715 0.0500905158733673 DYNLL1/HLA-DRB1/LRP1/PHPT1/SRI 5 GO:0070670 response to interleukin-4 5/566 36/18722 0.00430922452369715 0.0500905158733673 RPL3/RPLP0/HSP90AB1/TUBA1B/IMPDH2 5 GO:0090322 regulation of superoxide metabolic process 5/566 36/18722 0.00430922452369715 0.0500905158733673 TYROBP/CYBA/GSTP1/EGFR/GNAI3 5 GO:0001819 positive regulation of cytokine production 25/566 467/18722 0.00436202194794363 0.0503101598762825 GAPDH/RPS3/CD74/MIF/HMGB2/HMGB1/TYROBP/FCER1G/HLA-DPA1/HLA-A/ANXA1/HLA-DPB1/LRP1/IL6ST/CYBA/ISL1/B2M/PARK7/HSPD1/STOML2/CD46/APP/AIF1/SERPINE1/MNDA 25 GO:0019439 aromatic compound catabolic process 25/566 467/18722 0.00436202194794363 0.0503101598762825 NPM1/YBX1/VIM/EIF3E/YBX3/LSM6/HNRNPM/HNRNPC/MAGOH/SSB/LSM4/RBM8A/EIF4A3/DUT/LSM5/HNRNPD/CIRBP/RNASEH2A/MTHFS/MAGOHB/DNPH1/NUDT15/ZCCHC17/SMG1/EXOSC9 25 GO:0033674 positive regulation of kinase activity 25/566 467/18722 0.00436202194794363 0.0503101598762825 NPM1/RPS3/CD74/HMGB1/HLA-DRB1/CALM1/FLT1/HSP90AB1/ATP2B4/PPIA/CKS1B/CCNB1/EGFR/PARK7/TXN/MET/CKS2/DAG1/PDCD10/IGF2/IQGAP1/PRLR/PIH1D1/DBF4/IGF1R 25 GO:0009206 purine ribonucleoside triphosphate biosynthetic process 7/566 68/18722 0.00438023829056834 0.0503897180093288 ALDOA/ENO1/NME1/IMPDH2/TMSB4X/STOML2/NME2 7 GO:0051960 regulation of nervous system development 24/566 443/18722 0.00445814333197315 0.0509351299675217 FN1/LRP2/SPP1/HMGB2/LRP1/IL6ST/SERPINE2/EGFR/B2M/PLXNA1/SEMA6D/SEMA3F/SPINT1/PLXNB1/NRP1/DAG1/CLSTN1/SERPINF1/MACF1/PLXNB2/MME/FAIM/UBE2V2/SEMA6A 24 GO:0014031 mesenchymal cell development 8/566 86/18722 0.00446197230173708 0.0509351299675217 FN1/LAMA5/ISL1/SEMA6D/SEMA3F/NRP1/FOLR1/SEMA6A 8 GO:0048864 stem cell development 8/566 86/18722 0.00446197230173708 0.0509351299675217 FN1/LAMA5/ISL1/SEMA6D/SEMA3F/NRP1/FOLR1/SEMA6A 8 GO:0007159 leukocyte cell-cell adhesion 21/566 371/18722 0.00462795058659677 0.0523842178888184 RPS3/CD74/LGALS1/HMGB1/HLA-DRB1/HLA-DPA1/HLA-A/ANXA1/HLA-DRA/HLA-DPB1/IL6ST/B2M/HSPD1/ITGB1/CD46/AIF1/DPP4/GPNMB/IGF2/OLR1/TFRC 21 GO:0010639 negative regulation of organelle organization 20/566 347/18722 0.00462915379517469 0.0523842178888184 NPM1/PFN1/HNRNPA1/SLC25A5/STMN1/MAD2L1/HNRNPC/TMSB10/CCNB1/GPX1/BUB3/TRIAP1/PTTG1/GHITM/MET/TMSB4X/ZWINT/BNIP3/SCIN/TFRC 20 GO:0009162 deoxyribonucleoside monophosphate metabolic process 4/566 23/18722 0.00463236950208291 0.0523842178888184 TYMS/DUT/TK1/DNPH1 4 GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 14/566 209/18722 0.00464774619633497 0.0523842178888184 RPS3/HMGB1/CYCS/PRDX3/BIRC5/GPX1/PARK7/TRIAP1/HSPD1/HSPE1/PDCD5/CTSD/PIH1D1/PDCD2 14 GO:1902905 positive regulation of supramolecular fiber organization 14/566 209/18722 0.00464774619633497 0.0523842178888184 RPS3/PFN1/APOE/GPX1/S100A10/ARPC2/ARPC5/MET/NRP1/ARPC1A/AKAP9/APP/SCIN/CLIP1 14 GO:0032102 negative regulation of response to external stimulus 23/566 420/18722 0.00466851338986307 0.0524854081102788 MIF/APOE/SPP1/HLA-B/HLA-DRB1/HLA-A/SERPINE2/GSTP1/ISL1/RPS19/GPX1/SEMA6D/SEMA3F/NRP1/GRN/PBK/AIF1/SERPINF1/DPP4/GJA1/SERPINE1/HTRA1/SEMA6A 23 GO:0009145 purine nucleoside triphosphate biosynthetic process 7/566 69/18722 0.00475084841875874 0.0532765167766093 ALDOA/ENO1/NME1/IMPDH2/TMSB4X/STOML2/NME2 7 GO:0010594 regulation of endothelial cell migration 15/566 232/18722 0.00479950871082149 0.0536466467454255 APOE/HMGB1/ANXA1/ATP2B4/SPARC/LGMN/ANXA3/MET/TMSB4X/NRP1/GRN/PDCD10/SERPINF1/PLPP3/CALR 15 GO:0001906 cell killing 13/566 188/18722 0.00481074385668938 0.0536466467454255 GAPDH/LYZ/HLA-B/HLA-DRB1/HSP90AB1/TYROBP/HLA-A/PRDX1/HLA-DRA/HMGN2/TUBB4B/RPS19/B2M 13 GO:0042063 gliogenesis 18/566 301/18722 0.00483205421044825 0.0536466467454255 LRP2/VIM/ANXA1/LRP1/IL6ST/SERPINE2/GSTP1/EGFR/CDK1/ADGRG1/LAMB1/SPINT1/GRN/DAG1/ITGB4/BNIP3/APP/HEXB 18 GO:0042886 amide transport 18/566 301/18722 0.00483205421044825 0.0536466467454255 CD74/LRP2/DYNLL1/HLA-DRB1/ANXA1/LRP1/PSAP/EGFR/ISL1/PHPT1/PARK7/SLC19A1/ABCA1/DPP4/LRP5/SRI/GJA1/FOLR1 18 GO:0009886 post-embryonic animal morphogenesis 3/566 12/18722 0.00493114666193089 0.0539397172946347 FBN1/HMGN1/EFEMP1 3 GO:0021559 trigeminal nerve development 3/566 12/18722 0.00493114666193089 0.0539397172946347 ISL1/SEMA3F/NRP1 3 GO:0043380 regulation of memory T cell differentiation 3/566 12/18722 0.00493114666193089 0.0539397172946347 HLA-DRB1/HLA-DRA/CD46 3 GO:0070493 thrombin-activated receptor signaling pathway 3/566 12/18722 0.00493114666193089 0.0539397172946347 STMN1/HPGD/MET 3 GO:0071635 negative regulation of transforming growth factor beta production 3/566 12/18722 0.00493114666193089 0.0539397172946347 FN1/HSP90AB1/TYROBP 3 GO:2001204 regulation of osteoclast development 3/566 12/18722 0.00493114666193089 0.0539397172946347 FBN1/TYROBP/ATP6AP1 3 GO:1902850 microtubule cytoskeleton organization involved in mitosis 11/566 147/18722 0.00512017828319934 0.0556219514149689 RAN/STMN1/MAD2L1/SPC25/CCNB1/NUDC/CHMP5/ITGB1/CDC20/GJA1/CENPH 11 GO:0000070 mitotic sister chromatid segregation 12/566 168/18722 0.00513174755138477 0.0556219514149689 RAN/MAD2L1/CCNB1/NUDC/BUB3/CHMP5/CENPK/PTTG1/ZWINT/CDC20/ANAPC11/CDC26 12 GO:0002381 immunoglobulin production involved in immunoglobulin-mediated immune response 7/566 70/18722 0.00514459039864702 0.0556219514149689 HLA-DRB1/HLA-DPA1/HLA-DRA/HLA-DPB1/B2M/HSPD1/TFRC 7 GO:0002548 monocyte chemotaxis 7/566 70/18722 0.00514459039864702 0.0556219514149689 HMGB1/FLT1/ANXA1/RPS19/LGMN/AIF1/SERPINE1 7 GO:0006275 regulation of DNA replication 9/566 107/18722 0.00514740430884258 0.0556219514149689 EGFR/CACYBP/CDK1/RFC2/GMNN/STOML2/RFC3/CCNA2/DBF4 9 GO:0051222 positive regulation of protein transport 18/566 303/18722 0.00517004118023199 0.0557312913665686 DYNLL1/RAN/HLA-DRB1/HSP90AB1/NUTF2/PPIA/LRP1/UBE2L3/CDH1/EGFR/ISL1/PHPT1/CDK1/OAZ1/PDCD10/PDCD5/SRI/GJA1 18 GO:2000116 regulation of cysteine-type endopeptidase activity 15/566 235/18722 0.00539448818786501 0.0580102932666063 RPS3/HMGB1/CYCS/PRDX3/BIRC5/LGMN/GPX1/PARK7/TRIAP1/HSPD1/HSPE1/PDCD5/CTSD/PIH1D1/PDCD2 15 GO:0003148 outflow tract septum morphogenesis 4/566 24/18722 0.00542794103682924 0.058229381917985 LRP2/ISL1/NRP1/ENG 4 GO:0042596 fear response 5/566 38/18722 0.00546102732337664 0.0583033420711578 APOE/VDAC1/DPP4/GJA1/ADRB1 5 GO:0097242 amyloid-beta clearance 5/566 38/18722 0.00546102732337664 0.0583033420711578 LRP2/APOE/LRP1/MME/IGF1R 5 GO:0048638 regulation of developmental growth 19/566 330/18722 0.00575647512483559 0.0611642655268927 FN1/APOE/SPP1/YBX3/LRP1/CCNB1/CDK1/LGMN/SLC6A4/SEMA6D/SEMA3F/CGA/NRP1/APP/IGF2/MACF1/GJA1/ADRB1/SEMA6A 19 GO:0070371 ERK1 and ERK2 cascade 19/566 330/18722 0.00575647512483559 0.0611642655268927 FN1/CD74/MIF/APOE/HMGB1/HLA-DRB1/LRP1/GSTP1/EGFR/CDK1/ITGAV/NRP1/APP/GPNMB/TIMP3/FBLN1/ATP6AP1/SEMA6A/P2RY6 19 GO:0005977 glycogen metabolic process 7/566 72/18722 0.00600497259535266 0.063268909796863 HMGB1/IL6ST/PTGES3/PPP1CA/UGP2/IGF2/GAA 7 GO:0033045 regulation of sister chromatid segregation 7/566 72/18722 0.00600497259535266 0.063268909796863 MAD2L1/CCNB1/BUB3/PTTG1/ZWINT/ANAPC11/CDC26 7 GO:1905818 regulation of chromosome separation 7/566 72/18722 0.00600497259535266 0.063268909796863 MAD2L1/CCNB1/BUB3/PTTG1/ZWINT/ANAPC11/CDC26 7 GO:0001914 regulation of T cell mediated cytotoxicity 5/566 39/18722 0.0061115390793563 0.063268909796863 HLA-B/HLA-DRB1/HLA-A/HLA-DRA/B2M 5 GO:0002347 response to tumor cell 5/566 39/18722 0.0061115390793563 0.063268909796863 HMGB1/HLA-DRB1/HLA-A/HSPD1/TXNIP 5 GO:0051084 'de novo' posttranslational protein folding 5/566 39/18722 0.0061115390793563 0.063268909796863 CD74/PTGES3/HSPA9/CCT2/HSPE1 5 GO:0061387 regulation of extent of cell growth 9/566 110/18722 0.0061596532912138 0.063268909796863 FN1/APOE/SPP1/LRP1/SEMA6D/SEMA3F/NRP1/MACF1/SEMA6A 9 GO:1990138 neuron projection extension 12/566 172/18722 0.00617004595184701 0.063268909796863 FN1/APOE/HSP90AB1/LRP1/PLXNA1/SEMA6D/SEMA3F/NRP1/ITGB1/IQGAP1/MACF1/SEMA6A 12 GO:2001236 regulation of extrinsic apoptotic signaling pathway 11/566 151/18722 0.00624563471330443 0.063268909796863 HMGB2/GSTP1/PPP1CA/GPX1/PARK7/ITGA6/ITGAV/NRP1/TIMP3/SERPINE1/FAIM 11 GO:0010755 regulation of plasminogen activation 3/566 13/18722 0.00626787668413706 0.063268909796863 ENO1/SERPINE2/SERPINE1 3 GO:0032429 regulation of phospholipase A2 activity 3/566 13/18722 0.00626787668413706 0.063268909796863 ANXA1/LRP1/EGFR 3 GO:0033700 phospholipid efflux 3/566 13/18722 0.00626787668413706 0.063268909796863 APOC1/APOE/ABCA1 3 GO:0043379 memory T cell differentiation 3/566 13/18722 0.00626787668413706 0.063268909796863 HLA-DRB1/HLA-DRA/CD46 3 GO:0048012 hepatocyte growth factor receptor signaling pathway 3/566 13/18722 0.00626787668413706 0.063268909796863 STMN1/MET/NRP1 3 GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 3/566 13/18722 0.00626787668413706 0.063268909796863 CALM1/GSTO1/SRI 3 GO:1900115 extracellular regulation of signal transduction 3/566 13/18722 0.00626787668413706 0.063268909796863 FBN2/FBN1/CD46 3 GO:1900116 extracellular negative regulation of signal transduction 3/566 13/18722 0.00626787668413706 0.063268909796863 FBN2/FBN1/CD46 3 GO:1900272 negative regulation of long-term synaptic potentiation 3/566 13/18722 0.00626787668413706 0.063268909796863 APOE/TYROBP/APP 3 GO:0014033 neural crest cell differentiation 8/566 91/18722 0.00627324550383983 0.063268909796863 FN1/LAMA5/ISL1/SEMA6D/SEMA3F/NRP1/FOLR1/SEMA6A 8 GO:0051983 regulation of chromosome segregation 8/566 91/18722 0.00627324550383983 0.063268909796863 MAD2L1/CCNB1/BUB3/PTTG1/ZWINT/ANAPC11/CDC26/MKI67 8 GO:0072593 reactive oxygen species metabolic process 15/566 239/18722 0.00627917332838939 0.063268909796863 TYROBP/VDAC1/PRDX1/CYBA/GSTP1/EGFR/PRDX3/GPX1/PARK7/HBA2/HSPD1/BNIP3/NDUFS3/GNAI3/HBB 15 GO:0022604 regulation of cell morphogenesis 18/566 309/18722 0.00630198225942524 0.063268909796863 FN1/ALDOA/ANXA1/SPARC/PLXNA1/S100A10/ARPC2/CFL1/PLXNB1/MYL12A/NRP1/DAG1/HEXB/MACF1/FBLN1/PLXNB2/P4HB/CALR 18 GO:0009147 pyrimidine nucleoside triphosphate metabolic process 4/566 25/18722 0.0063098373651858 0.063268909796863 TYMS/NME1/DUT/NME2 4 GO:0033119 negative regulation of RNA splicing 4/566 25/18722 0.0063098373651858 0.063268909796863 NPM1/RPS13/SRSF7/SRSF9 4 GO:0048143 astrocyte activation 4/566 25/18722 0.0063098373651858 0.063268909796863 LRP1/EGFR/GRN/APP 4 GO:0007596 blood coagulation 14/566 217/18722 0.00643392389876687 0.0643681554995733 FN1/APOE/F5/ACTG1/FCER1G/PPIA/IL6ST/SERPINE2/ANXA5/MYL12A/LMAN1/FBLN1/HBB/SERPINE1 14 GO:0006073 cellular glucan metabolic process 7/566 73/18722 0.00647337240578961 0.064473051343569 HMGB1/IL6ST/PTGES3/PPP1CA/UGP2/IGF2/GAA 7 GO:0044042 glucan metabolic process 7/566 73/18722 0.00647337240578961 0.064473051343569 HMGB1/IL6ST/PTGES3/PPP1CA/UGP2/IGF2/GAA 7 GO:2000146 negative regulation of cell motility 20/566 359/18722 0.0066823518196821 0.0662125780516814 CD74/MIF/APOE/HMGB1/ATP2B4/LRP1/CDH1/GSTP1/ADGRG1/SEMA6D/ENG/DAG1/PDCD10/AIF1/SERPINF1/DPP4/FBLN1/GJA1/SERPINE1/CALR 20 GO:1903312 negative regulation of mRNA metabolic process 8/566 92/18722 0.00669411745397695 0.0662125780516814 NPM1/YBX1/YBX3/SRSF7/HNRNPC/SRSF9/HNRNPD/CIRBP 8 GO:0001912 positive regulation of leukocyte mediated cytotoxicity 6/566 56/18722 0.00670751857621481 0.0662125780516814 HLA-B/HLA-DRB1/TYROBP/HLA-A/HLA-DRA/B2M 6 GO:0002711 positive regulation of T cell mediated immunity 6/566 56/18722 0.00670751857621481 0.0662125780516814 HLA-B/HLA-DRB1/HLA-A/HLA-DRA/B2M/HSPD1 6 GO:0007584 response to nutrient 12/566 174/18722 0.00674807973151473 0.0664655994794327 LDHA/SPP1/TYMS/GSTP1/EGFR/SPARC/SLC6A4/COX4I1/HAT1/ABCA1/ATP2B1/FOLR1 12 GO:0071824 protein-DNA complex subunit organization 15/566 241/18722 0.00676334316701124 0.0664688825155277 NPM1/RPL23/HMGB2/HMGB1/DNAJC9/POLE3/CENPK/CENPN/ITGB3BP/GMNN/HAT1/SUPT16H/RAD51/PIH1D1/CENPH 15 GO:0045740 positive regulation of DNA replication 5/566 40/18722 0.00681462957053264 0.0668253983436373 EGFR/CACYBP/CDK1/STOML2/DBF4 5 GO:0007569 cell aging 10/566 132/18722 0.00683013842414895 0.0668302775039805 NPM1/MIF/YBX1/EEF1E1/CDK1/B2M/RSL1D1/MME/SERPINE1/CALR 10 GO:0034599 cellular response to oxidative stress 17/566 288/18722 0.00687945270571367 0.0671651829952572 RPS3/ANXA1/PRDX1/PPIA/EGFR/PRDX3/CDK1/GPX1/PARK7/TXN/MET/CHCHD2/PDCD10/BNIP3/AIF1/NME2/P4HB 17 GO:0000956 nuclear-transcribed mRNA catabolic process 9/566 112/18722 0.00691518473859089 0.0672959003481636 EIF3E/MAGOH/SSB/LSM4/RBM8A/EIF4A3/MAGOHB/SMG1/EXOSC9 9 GO:1903037 regulation of leukocyte cell-cell adhesion 19/566 336/18722 0.00693653805382048 0.0672959003481636 RPS3/CD74/LGALS1/HMGB1/HLA-DRB1/HLA-DPA1/HLA-A/ANXA1/HLA-DRA/HLA-DPB1/IL6ST/B2M/HSPD1/CD46/AIF1/DPP4/GPNMB/IGF2/TFRC 19 GO:0097191 extrinsic apoptotic signaling pathway 14/566 219/18722 0.00695679684920294 0.0672959003481636 HMGB2/GSTP1/PPP1CA/GPX1/PARK7/ITGA6/KRT8/ITGAV/NRP1/GABARAP/KRT18/TIMP3/SERPINE1/FAIM 14 GO:0009201 ribonucleoside triphosphate biosynthetic process 7/566 74/18722 0.00696842094800166 0.0672959003481636 ALDOA/ENO1/NME1/IMPDH2/TMSB4X/STOML2/NME2 7 GO:0048844 artery morphogenesis 7/566 74/18722 0.00696842094800166 0.0672959003481636 LRP2/APOE/LRP1/HPGD/NRP1/ENG/FOLR1 7 GO:0071248 cellular response to metal ion 13/566 197/18722 0.00706470419446741 0.0680780586012314 AOC1/CDH1/CCNB1/EGFR/CACYBP/LGMN/B2M/MT2A/BNIP3/APP/SERPINF1/IQGAP1/CALR 13 GO:0032755 positive regulation of interleukin-6 production 8/566 93/18722 0.00713600549365031 0.0686166230188579 CD74/HMGB1/TYROBP/CYBA/ISL1/HSPD1/APP/AIF1 8 GO:0045860 positive regulation of protein kinase activity 21/566 386/18722 0.0071829526967517 0.0689191926852124 NPM1/RPS3/HMGB1/CALM1/FLT1/HSP90AB1/ATP2B4/PPIA/CKS1B/CCNB1/EGFR/PARK7/TXN/CKS2/DAG1/PDCD10/IGF2/IQGAP1/PRLR/PIH1D1/DBF4 21 GO:0050770 regulation of axonogenesis 11/566 154/18722 0.00721048422036778 0.0689485522833763 FN1/SPP1/LRP1/PLXNA1/SEMA6D/SEMA3F/PLXNB1/NRP1/MACF1/PLXNB2/SEMA6A 11 GO:0001573 ganglioside metabolic process 4/566 26/18722 0.00728186921246479 0.0689485522833763 ITGB8/HEXB/HEXA/GM2A 4 GO:0002026 regulation of the force of heart contraction 4/566 26/18722 0.00728186921246479 0.0689485522833763 ATP2B4/GLRX3/GAA/ADRB1 4 GO:0002418 immune response to tumor cell 4/566 26/18722 0.00728186921246479 0.0689485522833763 HMGB1/HLA-DRB1/HLA-A/HSPD1 4 GO:0006760 folic acid-containing compound metabolic process 4/566 26/18722 0.00728186921246479 0.0689485522833763 TYMS/SLC19A1/MTHFS/FOLR1 4 GO:0048843 negative regulation of axon extension involved in axon guidance 4/566 26/18722 0.00728186921246479 0.0689485522833763 SEMA6D/SEMA3F/NRP1/SEMA6A 4 GO:0006611 protein export from nucleus 6/566 57/18722 0.00730990940650351 0.0689485522833763 RAN/NUTF2/PARK7/TXN/HSPA9/CALR 6 GO:1900024 regulation of substrate adhesion-dependent cell spreading 6/566 57/18722 0.00730990940650351 0.0689485522833763 S100A10/ARPC2/NRP1/FBLN1/P4HB/CALR 6 GO:0034614 cellular response to reactive oxygen species 11/566 155/18722 0.00755670891961285 0.0708240461886594 RPS3/ANXA1/PRDX1/EGFR/PRDX3/CDK1/PARK7/TXN/MET/PDCD10/BNIP3 11 GO:1903364 positive regulation of cellular protein catabolic process 11/566 155/18722 0.00755670891961285 0.0708240461886594 LRP2/APOE/LRP1/SUMO2/DDA1/BAG2/GABARAP/CDC20/PSMC4/UBE2V2/TMEM259 11 GO:0042307 positive regulation of protein import into nucleus 5/566 41/18722 0.00757238229690069 0.0708240461886594 RAN/HSP90AB1/NUTF2/CDH1/CDK1 5 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading 5/566 41/18722 0.00757238229690069 0.0708240461886594 S100A10/ARPC2/NRP1/P4HB/CALR 5 GO:1990830 cellular response to leukemia inhibitory factor 8/566 94/18722 0.00759954781085468 0.0709291129013104 RPS16/SRSF3/SLC25A5/SRSF7/NCL/CACYBP/PDCD10/TFRC 8 GO:1903008 organelle disassembly 9/566 114/18722 0.00773974833933601 0.071342351816638 VDAC1/SLC25A5/CDK1/PARK7/FUNDC2/GABARAP/VRK1/BNIP3/VPS13C 9 GO:0051348 negative regulation of transferase activity 16/566 268/18722 0.00774418241360085 0.071342351816638 NPM1/RPL5/RPL23/APOE/RPS20/DNAJA1/PPIA/RPL11/GSTP1/PKIB/MAD2L1/PHPT1/PRDX3/PARK7/BAG2/LRP5 16 GO:0009130 pyrimidine nucleoside monophosphate biosynthetic process 3/566 14/18722 0.00780010929351996 0.071342351816638 TYMS/DUT/UMPS 3 GO:0010421 hydrogen peroxide-mediated programmed cell death 3/566 14/18722 0.00780010929351996 0.071342351816638 PARK7/MET/PDCD10 3 GO:0046479 glycosphingolipid catabolic process 3/566 14/18722 0.00780010929351996 0.071342351816638 HEXB/HEXA/GM2A 3 GO:0046655 folic acid metabolic process 3/566 14/18722 0.00780010929351996 0.071342351816638 SLC19A1/MTHFS/FOLR1 3 GO:0090715 immunological memory formation process 3/566 14/18722 0.00780010929351996 0.071342351816638 HLA-DRB1/HLA-DRA/CD46 3 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 3/566 14/18722 0.00780010929351996 0.071342351816638 CD74/MIF/TRIAP1 3 GO:0007599 hemostasis 14/566 222/18722 0.00780407127913358 0.071342351816638 FN1/APOE/F5/ACTG1/FCER1G/PPIA/IL6ST/SERPINE2/ANXA5/MYL12A/LMAN1/FBLN1/HBB/SERPINE1 14 GO:0050817 coagulation 14/566 222/18722 0.00780407127913358 0.071342351816638 FN1/APOE/F5/ACTG1/FCER1G/PPIA/IL6ST/SERPINE2/ANXA5/MYL12A/LMAN1/FBLN1/HBB/SERPINE1 14 GO:0017148 negative regulation of translation 15/566 245/18722 0.00782144046305051 0.0713546166834034 GAPDH/RPS3/RPL13A/YBX1/EIF3E/TYMS/SRP9/NCL/EIF4A3/HNRNPD/CIRBP/MRPL13/MALSU1/EXOSC9/CALR 15 GO:0009123 nucleoside monophosphate metabolic process 7/566 76/18722 0.00804199478806708 0.0730672669315809 TYMS/DUT/IMPDH2/TK1/UMPS/DNPH1/GMPS 7 GO:0032543 mitochondrial translation 7/566 76/18722 0.00804199478806708 0.0730672669315809 MRPS15/MRPL51/MRPS35/MRPS6/MRPS7/MALSU1/MRPS28 7 GO:0030516 regulation of axon extension 8/566 95/18722 0.00808538405610468 0.0731628654832887 FN1/APOE/LRP1/SEMA6D/SEMA3F/NRP1/MACF1/SEMA6A 8 GO:1990823 response to leukemia inhibitory factor 8/566 95/18722 0.00808538405610468 0.0731628654832887 RPS16/SRSF3/SLC25A5/SRSF7/NCL/CACYBP/PDCD10/TFRC 8 GO:0051402 neuron apoptotic process 15/566 246/18722 0.00810557502269121 0.0731967951339173 GAPDH/APOE/HSP90AB1/TYROBP/LRP1/ISL1/LGMN/GPX1/PARK7/HSPD1/NRP1/GRN/BNIP3/APP/UBE2V2 15 GO:0046916 cellular transition metal ion homeostasis 9/566 115/18722 0.00817912793670176 0.0737114930651746 FTL/MT2A/APP/GLRX3/SRI/SLC40A1/SLC39A10/ATP6AP1/TFRC 9 GO:0032786 positive regulation of DNA-templated transcription, elongation 4/566 27/18722 0.00834765743845707 0.0746764096337673 HMGN1/ALYREF/SUPT16H/GTF2F1 4 GO:0098901 regulation of cardiac muscle cell action potential 4/566 27/18722 0.00834765743845707 0.0746764096337673 CALM1/AKAP9/DSC2/DSG2 4 GO:0014912 negative regulation of smooth muscle cell migration 5/566 42/18722 0.0083868384584195 0.0746764096337673 LRP1/GSTP1/SEMA6D/AIF1/SERPINE1 5 GO:0045214 sarcomere organization 5/566 42/18722 0.0083868384584195 0.0746764096337673 KRT19/ACTG1/CSRP2/KRT8/ITGB1 5 GO:0046596 regulation of viral entry into host cell 5/566 42/18722 0.0083868384584195 0.0746764096337673 CD74/LGALS1/HLA-DRB1/IFITM2/P4HB 5 GO:0046688 response to copper ion 5/566 42/18722 0.0083868384584195 0.0746764096337673 AOC1/CDK1/PARK7/MT2A/APP 5 GO:0051271 negative regulation of cellular component movement 20/566 367/18722 0.00842556110732348 0.0748714531932218 CD74/MIF/APOE/HMGB1/ATP2B4/LRP1/CDH1/GSTP1/ADGRG1/SEMA6D/ENG/DAG1/PDCD10/AIF1/SERPINF1/DPP4/FBLN1/GJA1/SERPINE1/CALR 20 GO:0044264 cellular polysaccharide metabolic process 8/566 96/18722 0.00859415470426272 0.0761443821279029 HMGB1/IL6ST/PTGES3/PPP1CA/UGP2/IGF2/GAA/B3GNT3 8 GO:0006767 water-soluble vitamin metabolic process 6/566 59/18722 0.00863030704110595 0.0761443821279029 SLC2A1/SLC19A1/SLC52A1/MTHFS/GSTO1/FOLR1 6 GO:0090303 positive regulation of wound healing 6/566 59/18722 0.00863030704110595 0.0761443821279029 HMGB1/ACTG1/ANXA1/ITGB1/PLPP3/SERPINE1 6 GO:0007006 mitochondrial membrane organization 9/566 116/18722 0.00863722214164218 0.0761443821279029 CALM1/VDAC2/SLC25A5/HSPA9/GHITM/TOMM22/PDCD5/BNIP3/TIMM9 9 GO:0010977 negative regulation of neuron projection development 10/566 137/18722 0.00879022380906889 0.0773400719327563 APOE/SPP1/LGALS1/VIM/LRP1/B2M/SEMA6D/SEMA3F/NRP1/SEMA6A 10 GO:0030336 negative regulation of cell migration 19/566 344/18722 0.00880868126347717 0.0773496035207108 CD74/MIF/APOE/HMGB1/ATP2B4/LRP1/CDH1/GSTP1/ADGRG1/SEMA6D/ENG/DAG1/PDCD10/AIF1/SERPINF1/DPP4/GJA1/SERPINE1/CALR 19 GO:0034249 negative regulation of cellular amide metabolic process 16/566 273/18722 0.00915816920936152 0.0800494866770258 GAPDH/RPS3/APOE/RPL13A/YBX1/EIF3E/TYMS/SRP9/NCL/EIF4A3/HNRNPD/CIRBP/MRPL13/MALSU1/EXOSC9/CALR 16 GO:0055076 transition metal ion homeostasis 10/566 138/18722 0.00922927901150989 0.0800494866770258 FTL/B2M/MT2A/APP/GLRX3/SRI/SLC40A1/SLC39A10/ATP6AP1/TFRC 10 GO:0032024 positive regulation of insulin secretion 7/566 78/18722 0.00923273976098148 0.0800494866770258 DYNLL1/HLA-DRB1/LRP1/ISL1/PHPT1/SRI/GJA1 7 GO:0034637 cellular carbohydrate biosynthetic process 7/566 78/18722 0.00923273976098148 0.0800494866770258 PTGES3/PPP1CA/UGP2/B4GALT1/IMPA2/IGF2/B3GNT3 7 GO:0014002 astrocyte development 5/566 43/18722 0.00925999228182127 0.0800494866770258 VIM/LRP1/EGFR/GRN/APP 5 GO:0033046 negative regulation of sister chromatid segregation 5/566 43/18722 0.00925999228182127 0.0800494866770258 MAD2L1/CCNB1/BUB3/PTTG1/ZWINT 5 GO:0033048 negative regulation of mitotic sister chromatid segregation 5/566 43/18722 0.00925999228182127 0.0800494866770258 MAD2L1/CCNB1/BUB3/PTTG1/ZWINT 5 GO:2000816 negative regulation of mitotic sister chromatid separation 5/566 43/18722 0.00925999228182127 0.0800494866770258 MAD2L1/CCNB1/BUB3/PTTG1/ZWINT 5 GO:0030071 regulation of mitotic metaphase/anaphase transition 6/566 60/18722 0.00935086627095376 0.0806784043377639 MAD2L1/CCNB1/BUB3/ZWINT/ANAPC11/CDC26 6 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3/566 15/18722 0.00953391768993477 0.0806939193072046 RPL7/NIFK/RPL7L1 3 GO:0002468 dendritic cell antigen processing and presentation 3/566 15/18722 0.00953391768993477 0.0806939193072046 CD74/HLA-DRB1/HLA-DRA 3 GO:0009263 deoxyribonucleotide biosynthetic process 3/566 15/18722 0.00953391768993477 0.0806939193072046 TYMS/DUT/RRM2 3 GO:0032488 Cdc42 protein signal transduction 3/566 15/18722 0.00953391768993477 0.0806939193072046 APOE/NRP1/ABCA1 3 GO:0048308 organelle inheritance 3/566 15/18722 0.00953391768993477 0.0806939193072046 CDK1/PDCD10/VRK1 3 GO:0048313 Golgi inheritance 3/566 15/18722 0.00953391768993477 0.0806939193072046 CDK1/PDCD10/VRK1 3 GO:0051284 positive regulation of sequestering of calcium ion 3/566 15/18722 0.00953391768993477 0.0806939193072046 CALM1/GSTO1/SRI 3 GO:0097468 programmed cell death in response to reactive oxygen species 3/566 15/18722 0.00953391768993477 0.0806939193072046 PARK7/MET/PDCD10 3 GO:1901660 calcium ion export 3/566 15/18722 0.00953391768993477 0.0806939193072046 CALM1/ATP2B4/ATP2B1 3 GO:2001028 positive regulation of endothelial cell chemotaxis 3/566 15/18722 0.00953391768993477 0.0806939193072046 LGMN/MET/TMSB4X 3 GO:0030203 glycosaminoglycan metabolic process 9/566 118/18722 0.00961150996385938 0.0811962853113889 CHPF/GNS/ITIH5/HEXB/NAGLU/HS6ST2/GLB1/B3GNT3/HEXA 9 GO:0070301 cellular response to hydrogen peroxide 8/566 98/18722 0.00968306138149882 0.0813532757478395 RPS3/ANXA1/CDK1/PARK7/TXN/MET/PDCD10/BNIP3 8 GO:1904029 regulation of cyclin-dependent protein kinase activity 8/566 98/18722 0.00968306138149882 0.0813532757478395 HSP90AB1/CKS1B/CCNB1/EGFR/CCNE1/CKS2/CCNB2/CCNA2 8 GO:0051783 regulation of nuclear division 10/566 139/18722 0.0096849137795047 0.0813532757478395 MAD2L1/CCNB1/BUB3/ZWINT/CDC20/ANAPC11/IGF2/LRP5/MKI67/CALR 10 GO:0022407 regulation of cell-cell adhesion 23/566 448/18722 0.00983939262136563 0.0824952466107717 RPS3/CD74/LGALS1/HMGB1/HLA-DRB1/HLA-DPA1/HLA-A/ANXA1/HLA-DRA/HLA-DPB1/IL6ST/CDH1/SERPINE2/B2M/TENM3/HSPD1/CD46/AIF1/DPP4/GPNMB/IGF2/PLPP3/TFRC 23 GO:0050772 positive regulation of axonogenesis 7/566 79/18722 0.00987424040060316 0.0826318012471528 FN1/LRP1/PLXNA1/PLXNB1/NRP1/MACF1/PLXNB2 7 GO:0010038 response to metal ion 20/566 373/18722 0.00996094927373879 0.0832010247029739 AOC1/CALM1/CDH1/CCNB1/EGFR/CACYBP/SPARC/CDK1/PPP1CA/LGMN/B2M/PARK7/MT2A/HNRNPD/BNIP3/APP/SERPINF1/IQGAP1/TXNIP/CALR 20 GO:0008016 regulation of heart contraction 13/566 206/18722 0.0100843083116984 0.0840736715424746 CALM1/ATP2B4/ISL1/AKAP9/GSTO1/DSC2/GLRX3/GAA/SRI/GJA1/ATP2B1/DSG2/ADRB1 13 GO:0031333 negative regulation of protein-containing complex assembly 10/566 140/18722 0.010157516193956 0.0845116165445882 PFN1/RPL13A/HMGB1/VDAC2/STMN1/TMSB10/ISL1/PARK7/TMSB4X/SCIN 10 GO:0009262 deoxyribonucleotide metabolic process 5/566 44/18722 0.0101937866317259 0.0845116165445882 TYMS/DUT/RRM2/DNPH1/NUDT15 5 GO:0042554 superoxide anion generation 5/566 44/18722 0.0101937866317259 0.0845116165445882 TYROBP/CYBA/GSTP1/EGFR/GNAI3 5 GO:0051100 negative regulation of binding 11/566 162/18722 0.0103565110539635 0.0857010914725757 C4orf3/PTPRF/PPP1CA/B2M/EIF4A3/PARK7/TMSB4X/BAG2/ZNF593/SRI/GTF2F1 11 GO:0030198 extracellular matrix organization 17/566 301/18722 0.0104237849772474 0.0860977564354461 COL4A2/ADAMTSL4/QSOX1/LRP1/LAMC1/COL4A1/ADAMTS6/COL14A1/LAMB1/SPINT1/ITGB1/B4GALT1/ENG/DAG1/APP/DPP4/FBLN1 17 GO:0030595 leukocyte chemotaxis 14/566 230/18722 0.0104678353906314 0.0861916852889657 CD74/MIF/HMGB1/FLT1/CSF3R/FCER1G/ANXA1/PPIA/RPS19/LGMN/AIF1/DPP4/SERPINE1/CALR 14 GO:0050679 positive regulation of epithelial cell proliferation 13/566 207/18722 0.0104738773003887 0.0861916852889657 HMGB2/HMGB1/LAMC1/CYBA/NME1/EGFR/LAMB1/NRP1/B4GALT1/GRN/IGF2/NME2/HTRA1 13 GO:0032355 response to estradiol 10/566 141/18722 0.010647475021881 0.0870522823283192 ANXA1/GSTP1/EGFR/HPGD/SLC6A4/HNRNPD/CCNA2/GJA1/TXNIP/CALR 10 GO:0034341 response to interferon-gamma 10/566 141/18722 0.010647475021881 0.0870522823283192 GAPDH/CD74/RPL13A/VIM/ACTG1/HSP90AB1/HLA-DPA1/IFITM2/AIF1/SEC61A1 10 GO:0051896 regulation of protein kinase B signaling 12/566 185/18722 0.0107305577697679 0.0870522823283192 LRP2/HSP90AB1/EGFR/GPX1/PARK7/TXN/MET/ITGB1/ENG/DAG1/IGF2/IGF1R 12 GO:0043062 extracellular structure organization 17/566 302/18722 0.0107473862843925 0.0870522823283192 COL4A2/ADAMTSL4/QSOX1/LRP1/LAMC1/COL4A1/ADAMTS6/COL14A1/LAMB1/SPINT1/ITGB1/B4GALT1/ENG/DAG1/APP/DPP4/FBLN1 17 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity 4/566 29/18722 0.0107739909170943 0.0870522823283192 CKS1B/CCNB1/EGFR/CKS2 4 GO:0048679 regulation of axon regeneration 4/566 29/18722 0.0107739909170943 0.0870522823283192 SPP1/LRP1/PTPRF/GRN 4 GO:0090025 regulation of monocyte chemotaxis 4/566 29/18722 0.0107739909170943 0.0870522823283192 HMGB1/LGMN/AIF1/SERPINE1 4 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 4/566 29/18722 0.0107739909170943 0.0870522823283192 PPIA/GPX1/PARK7/P4HB 4 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage 4/566 29/18722 0.0107739909170943 0.0870522823283192 TPT1/CD74/MIF/TRIAP1 4 GO:1903902 positive regulation of viral life cycle 4/566 29/18722 0.0107739909170943 0.0870522823283192 CD74/LGALS1/HLA-DRB1/P4HB 4 GO:0060840 artery development 8/566 100/18722 0.0108713837244222 0.087551182072627 LRP2/APOE/LRP1/ADAMTS6/HPGD/NRP1/ENG/FOLR1 8 GO:1901215 negative regulation of neuron death 13/566 208/18722 0.0108750682134238 0.087551182072627 APOE/HSP90AB1/LRP1/ISL1/LGMN/PARK7/HSPD1/NRP1/GRN/SERPINF1/GPNMB/UBE2V2/TMEM259 13 GO:0007091 metaphase/anaphase transition of mitotic cell cycle 6/566 62/18722 0.0109189738946051 0.0877459779400396 MAD2L1/CCNB1/BUB3/ZWINT/ANAPC11/CDC26 6 GO:0032103 positive regulation of response to external stimulus 22/566 427/18722 0.0109896608404707 0.0881549010122085 NEAT1/CD74/HMGB2/HMGB1/TYROBP/LRP1/IL6ST/CYBA/EGFR/RPS19/LGMN/PARK7/HSPD1/MET/TMSB4X/NRP1/GRN/APP/AIF1/SERPINE1/MNDA/CALR 22 GO:0002263 cell activation involved in immune response 16/566 279/18722 0.0111181994401151 0.0883634256305742 RPS6/CD74/LGALS1/HMGB1/HLA-DRB1/TYROBP/FCER1G/ANXA1/HLA-DRA/LRP1/ANXA3/HSPD1/GRN/CD46/APP/TFRC 16 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress 5/566 45/18722 0.0111901089071808 0.0883634256305742 PPIA/GPX1/PARK7/PDCD10/P4HB 5 GO:0035272 exocrine system development 5/566 45/18722 0.0111901089071808 0.0883634256305742 LAMA5/PLXNA1/NRP1/DAG1/IGF2 5 GO:0051180 vitamin transport 5/566 45/18722 0.0111901089071808 0.0883634256305742 LRP2/SLC2A1/SLC19A1/SLC52A1/FOLR1 5 GO:0051985 negative regulation of chromosome segregation 5/566 45/18722 0.0111901089071808 0.0883634256305742 MAD2L1/CCNB1/BUB3/PTTG1/ZWINT 5 GO:0071364 cellular response to epidermal growth factor stimulus 5/566 45/18722 0.0111901089071808 0.0883634256305742 EEF1A1/GSTP1/NCL/EGFR/IQGAP1 5 GO:1904646 cellular response to amyloid-beta 5/566 45/18722 0.0111901089071808 0.0883634256305742 LRP1/LGMN/APP/GJA1/IGF1R 5 GO:1905819 negative regulation of chromosome separation 5/566 45/18722 0.0111901089071808 0.0883634256305742 MAD2L1/CCNB1/BUB3/PTTG1/ZWINT 5 GO:0000422 autophagy of mitochondrion 7/566 81/18722 0.0112538325095543 0.0883634256305742 VDAC1/SLC25A5/PARK7/FUNDC2/GABARAP/BNIP3/VPS13C 7 GO:0006096 glycolytic process 7/566 81/18722 0.0112538325095543 0.0883634256305742 GAPDH/LDHA/TPI1/ALDOA/ENO1/PKM/APP 7 GO:0048708 astrocyte differentiation 7/566 81/18722 0.0112538325095543 0.0883634256305742 VIM/LRP1/IL6ST/SERPINE2/EGFR/GRN/APP 7 GO:0061726 mitochondrion disassembly 7/566 81/18722 0.0112538325095543 0.0883634256305742 VDAC1/SLC25A5/PARK7/FUNDC2/GABARAP/BNIP3/VPS13C 7 GO:0031346 positive regulation of cell projection organization 19/566 353/18722 0.0113805860912333 0.0886864522302374 FN1/PFN1/APOE/LRP1/NME1/ITGA6/PLXNA1/ARPC2/PLXNB1/TENM3/NRP1/GRN/SERPINF1/IQGAP1/MACF1/PLXNB2/NME2/P3H1/UBE2V2 19 GO:0045229 external encapsulating structure organization 17/566 304/18722 0.0114184770538421 0.0886864522302374 COL4A2/ADAMTSL4/QSOX1/LRP1/LAMC1/COL4A1/ADAMTS6/COL14A1/LAMB1/SPINT1/ITGB1/B4GALT1/ENG/DAG1/APP/DPP4/FBLN1 17 GO:0005980 glycogen catabolic process 3/566 16/18722 0.0114742579704889 0.0886864522302374 HMGB1/PPP1CA/GAA 3 GO:0010649 regulation of cell communication by electrical coupling 3/566 16/18722 0.0114742579704889 0.0886864522302374 CALM1/SRI/GJA1 3 GO:0017014 protein nitrosylation 3/566 16/18722 0.0114742579704889 0.0886864522302374 GAPDH/ATP2B4/TXN 3 GO:0018119 peptidyl-cysteine S-nitrosylation 3/566 16/18722 0.0114742579704889 0.0886864522302374 GAPDH/ATP2B4/TXN 3 GO:0019377 glycolipid catabolic process 3/566 16/18722 0.0114742579704889 0.0886864522302374 HEXB/HEXA/GM2A 3 GO:0033631 cell-cell adhesion mediated by integrin 3/566 16/18722 0.0114742579704889 0.0886864522302374 ITGB1/DPP4/PLPP3 3 GO:1905906 regulation of amyloid fibril formation 3/566 16/18722 0.0114742579704889 0.0886864522302374 APOE/APP/PFDN4 3 GO:0045637 regulation of myeloid cell differentiation 13/566 210/18722 0.0117132118187138 0.0903370342645406 FBN1/CD74/HMGB2/HMGB1/HLA-DRB1/TYROBP/CSF3R/NME1/B2M/HSPA9/SCIN/NME2/ATP6AP1 13 GO:0031343 positive regulation of cell killing 6/566 63/18722 0.0117689757128108 0.0903370342645406 HLA-B/HLA-DRB1/TYROBP/HLA-A/HLA-DRA/B2M 6 GO:1902099 regulation of metaphase/anaphase transition of cell cycle 6/566 63/18722 0.0117689757128108 0.0903370342645406 MAD2L1/CCNB1/BUB3/ZWINT/ANAPC11/CDC26 6 GO:1904589 regulation of protein import 6/566 63/18722 0.0117689757128108 0.0903370342645406 RAN/HSP90AB1/NUTF2/CDH1/CDK1/PDCD5 6 GO:0006757 ATP generation from ADP 7/566 82/18722 0.0119936375459554 0.0912286177330446 GAPDH/LDHA/TPI1/ALDOA/ENO1/PKM/APP 7 GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors 7/566 82/18722 0.0119936375459554 0.0912286177330446 HMGB2/GPX1/PARK7/GABARAP/TIMP3/SERPINE1/FAIM 7 GO:0072527 pyrimidine-containing compound metabolic process 7/566 82/18722 0.0119936375459554 0.0912286177330446 ERH/TYMS/NME1/DUT/TK1/UMPS/NME2 7 GO:0016049 cell growth 24/566 482/18722 0.0120281190633056 0.0912286177330446 FN1/NPM1/APOE/SPP1/HSP90AB1/ENO1/LRP1/CYBA/SERPINE2/EGFR/PLXNA1/SEMA6D/SEMA3F/NRP1/ITGB1/CLSTN1/APP/IQGAP1/MACF1/DNPH1/NDUFS3/GJA1/SEMA6A/EXOSC9 24 GO:0048588 developmental cell growth 14/566 234/18722 0.0120428673082192 0.0912286177330446 FN1/APOE/SPP1/HSP90AB1/LRP1/PLXNA1/SEMA6D/SEMA3F/NRP1/ITGB1/APP/IQGAP1/MACF1/SEMA6A 14 GO:0060560 developmental growth involved in morphogenesis 14/566 234/18722 0.0120428673082192 0.0912286177330446 FN1/APOE/SPP1/HSP90AB1/LRP1/PLXNA1/SEMA6D/SEMA3F/NRP1/ITGB1/APP/IQGAP1/MACF1/SEMA6A 14 GO:0006099 tricarboxylic acid cycle 4/566 30/18722 0.01214076435244 0.0912286177330446 MDH1/MDH2/SDHB/FH 4 GO:0034508 centromere complex assembly 4/566 30/18722 0.01214076435244 0.0912286177330446 CENPK/CENPN/ITGB3BP/CENPH 4 GO:0090151 establishment of protein localization to mitochondrial membrane 4/566 30/18722 0.01214076435244 0.0912286177330446 CALM1/TOMM22/PDCD5/TIMM9 4 GO:1902751 positive regulation of cell cycle G2/M phase transition 4/566 30/18722 0.01214076435244 0.0912286177330446 NPM1/CCNB1/CDK1/APP 4 GO:0042593 glucose homeostasis 15/566 258/18722 0.0121983353086502 0.0912286177330446 RPS6/LGALS1/DYNLL1/HLA-DRB1/LRP1/CYBA/NME1/PHPT1/PARK7/SERPINF1/LRP5/SRI/PIH1D1/NME2/IGF1R 15 GO:0010821 regulation of mitochondrion organization 10/566 144/18722 0.0122253825183011 0.0912286177330446 VDAC1/SLC25A5/GPX1/PARK7/TRIAP1/GHITM/PDCD5/BNIP3/VPS13C/TFRC 10 GO:0033135 regulation of peptidyl-serine phosphorylation 10/566 144/18722 0.0122253825183011 0.0912286177330446 MIF/HSP90AB1/ATP2B4/EGFR/PARK7/TXN/PDCD10/AKAP9/APP/TFRC 10 GO:0033047 regulation of mitotic sister chromatid segregation 5/566 46/18722 0.0122507872234042 0.0912286177330446 MAD2L1/CCNB1/BUB3/PTTG1/ZWINT 5 GO:0050919 negative chemotaxis 5/566 46/18722 0.0122507872234042 0.0912286177330446 SEMA6D/SEMA3F/ITGAV/DPP4/SEMA6A 5 GO:0090329 regulation of DNA-dependent DNA replication 5/566 46/18722 0.0122507872234042 0.0912286177330446 RFC2/GMNN/STOML2/RFC3/DBF4 5 GO:1900271 regulation of long-term synaptic potentiation 5/566 46/18722 0.0122507872234042 0.0912286177330446 APOE/TYROBP/LGMN/APP/MME 5 GO:0007346 regulation of mitotic cell cycle 23/566 457/18722 0.0122539787521026 0.0912286177330446 RPL26/ANXA1/CKS1B/MAD2L1/CCNB1/EGFR/CDK1/LGMN/BUB3/RPA3/TRIAP1/CDK2AP2/CKS2/ZWINT/ANAPC11/APP/AIF1/GPNMB/IGF2/LRP5/IQGAP1/CDC26/MKI67 23 GO:0030099 myeloid cell differentiation 20/566 381/18722 0.0123497631017514 0.0917882225859718 RPS6/FBN1/CD74/HMGB2/HMGB1/HLA-DRB1/TYROBP/CSF3R/SLC25A5/NME1/PRDX3/RPS19/B2M/HSPA9/ITGB8/APP/SCIN/NME2/ATP6AP1/TFRC 20 GO:0010811 positive regulation of cell-substrate adhesion 9/566 123/18722 0.0124089964234331 0.0919215508770785 FN1/ITGA6/S100A10/ARPC2/NRP1/DAG1/IQGAP1/P4HB/CALR 9 GO:0030168 platelet activation 9/566 123/18722 0.0124089964234331 0.0919215508770785 FN1/APOE/ACTG1/FCER1G/PPIA/IL6ST/SERPINE2/MYL12A/HBB 9 GO:0033500 carbohydrate homeostasis 15/566 259/18722 0.0126013449212695 0.0931913415107841 RPS6/LGALS1/DYNLL1/HLA-DRB1/LRP1/CYBA/NME1/PHPT1/PARK7/SERPINF1/LRP5/SRI/PIH1D1/NME2/IGF1R 15 GO:0030888 regulation of B cell proliferation 6/566 64/18722 0.0126645438339406 0.0932929385818674 CD74/MIF/TYROBP/SLC39A10/MNDA/TFRC 6 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus 6/566 64/18722 0.0126645438339406 0.0932929385818674 DYNLL1/HLA-DRB1/LRP1/PHPT1/LRP5/SRI 6 GO:1902903 regulation of supramolecular fiber organization 20/566 382/18722 0.012677948751579 0.0932929385818674 RPS3/PFN1/APOE/ACTG1/STMN1/TMSB10/GPX1/PARK7/S100A10/ARPC2/ARPC5/MET/TMSB4X/NRP1/ARPC1A/AKAP9/APP/PFDN4/SCIN/CLIP1 20 GO:0043524 negative regulation of neuron apoptotic process 10/566 145/18722 0.012788659324083 0.0939523288957388 APOE/HSP90AB1/LRP1/ISL1/LGMN/PARK7/HSPD1/NRP1/GRN/UBE2V2 10 GO:0090277 positive regulation of peptide hormone secretion 8/566 103/18722 0.012851388769504 0.0942576322929684 DYNLL1/HLA-DRB1/LRP1/EGFR/ISL1/PHPT1/SRI/GJA1 8 GO:0009132 nucleoside diphosphate metabolic process 9/566 124/18722 0.0130344210133598 0.0954428328149309 GAPDH/LDHA/TPI1/ALDOA/ENO1/PKM/NME1/APP/NME2 9 GO:0002696 positive regulation of leukocyte activation 21/566 409/18722 0.0132383034507499 0.0955255334671515 RPS3/CD74/MIF/LGALS1/HMGB1/HLA-DRB1/TYROBP/HLA-DPA1/HLA-A/ANXA1/HLA-DRA/HLA-DPB1/IL6ST/B2M/HSPD1/CD46/AIF1/DPP4/IGF2/SLC39A10/TFRC 21 GO:0070372 regulation of ERK1 and ERK2 cascade 17/566 309/18722 0.0132416811679805 0.0955255334671515 FN1/CD74/MIF/APOE/HMGB1/HLA-DRB1/LRP1/GSTP1/EGFR/NRP1/APP/GPNMB/TIMP3/FBLN1/ATP6AP1/SEMA6A/P2RY6 17 GO:0042311 vasodilation 5/566 47/18722 0.0133775868773091 0.0955255334671515 APOE/EGFR/GPX1/GJA1/ADRB1 5 GO:0050885 neuromuscular process controlling balance 5/566 47/18722 0.0133775868773091 0.0955255334671515 APP/GAA/HEXB/IGDCC3/GM2A 5 GO:1903170 negative regulation of calcium ion transmembrane transport 5/566 47/18722 0.0133775868773091 0.0955255334671515 CALM1/VDAC1/C4orf3/GSTO1/SRI 5 GO:0006112 energy reserve metabolic process 7/566 84/18722 0.0135774858191137 0.0955255334671515 HMGB1/IL6ST/PTGES3/PPP1CA/UGP2/IGF2/GAA 7 GO:0006835 dicarboxylic acid transport 7/566 84/18722 0.0135774858191137 0.0955255334671515 LRP2/SLC26A2/SLC19A1/ITGB1/GJA1/FOLR1/SLC1A5 7 GO:0043489 RNA stabilization 6/566 65/18722 0.0136068501094304 0.0955255334671515 YBX1/YBX3/HNRNPC/HNRNPD/CIRBP/ZCCHC17 6 GO:0044784 metaphase/anaphase transition of cell cycle 6/566 65/18722 0.0136068501094304 0.0955255334671515 MAD2L1/CCNB1/BUB3/ZWINT/ANAPC11/CDC26 6 GO:0048524 positive regulation of viral process 6/566 65/18722 0.0136068501094304 0.0955255334671515 CD74/LGALS1/HLA-DRB1/PPIA/PPIH/P4HB 6 GO:0071677 positive regulation of mononuclear cell migration 6/566 65/18722 0.0136068501094304 0.0955255334671515 HMGB1/LGMN/APP/AIF1/SERPINE1/CALR 6 GO:0001516 prostaglandin biosynthetic process 4/566 31/18722 0.0136137416441405 0.0955255334671515 CD74/MIF/ANXA1/PTGES3 4 GO:0030149 sphingolipid catabolic process 4/566 31/18722 0.0136137416441405 0.0955255334671515 HEXB/ASAH1/HEXA/GM2A 4 GO:0036474 cell death in response to hydrogen peroxide 4/566 31/18722 0.0136137416441405 0.0955255334671515 PARK7/TXN/MET/PDCD10 4 GO:0046457 prostanoid biosynthetic process 4/566 31/18722 0.0136137416441405 0.0955255334671515 CD74/MIF/ANXA1/PTGES3 4 GO:0060055 angiogenesis involved in wound healing 4/566 31/18722 0.0136137416441405 0.0955255334671515 GPX1/B4GALT1/DAG1/SERPINE1 4 GO:0071711 basement membrane organization 4/566 31/18722 0.0136137416441405 0.0955255334671515 COL4A1/LAMB1/ITGB1/DAG1 4 GO:0009200 deoxyribonucleoside triphosphate metabolic process 3/566 17/18722 0.013625048012498 0.0955255334671515 TYMS/DUT/NUDT15 3 GO:0009251 glucan catabolic process 3/566 17/18722 0.013625048012498 0.0955255334671515 HMGB1/PPP1CA/GAA 3 GO:0016045 detection of bacterium 3/566 17/18722 0.013625048012498 0.0955255334671515 HLA-B/HLA-DRB1/HLA-A 3 GO:0036035 osteoclast development 3/566 17/18722 0.013625048012498 0.0955255334671515 FBN1/TYROBP/ATP6AP1 3 GO:0042339 keratan sulfate metabolic process 3/566 17/18722 0.013625048012498 0.0955255334671515 GNS/GLB1/B3GNT3 3 GO:0045591 positive regulation of regulatory T cell differentiation 3/566 17/18722 0.013625048012498 0.0955255334671515 HLA-DRB1/HLA-DRA/CD46 3 GO:0061298 retina vasculature development in camera-type eye 3/566 17/18722 0.013625048012498 0.0955255334671515 COL4A1/NRP1/LRP5 3 GO:0061450 trophoblast cell migration 3/566 17/18722 0.013625048012498 0.0955255334671515 ITGB4/GJA1/CALR 3 GO:0070206 protein trimerization 3/566 17/18722 0.013625048012498 0.0955255334671515 CD74/MIF/SLC1A5 3 GO:0090713 immunological memory process 3/566 17/18722 0.013625048012498 0.0955255334671515 HLA-DRB1/HLA-DRA/CD46 3 GO:0003018 vascular process in circulatory system 15/566 263/18722 0.0143182330338133 0.100227631236693 LRP2/APOE/ATP2B4/LRP1/EGFR/SLC2A1/SLC6A4/GPX1/SLC19A1/SLC38A2/GJA1/ATP2B1/ADRB1/TFRC/SLC1A5 15 GO:0002709 regulation of T cell mediated immunity 7/566 85/18722 0.0144231872152905 0.100645814235852 HLA-B/HMGB1/HLA-DRB1/HLA-A/HLA-DRA/B2M/HSPD1 7 GO:0055072 iron ion homeostasis 7/566 85/18722 0.0144231872152905 0.100645814235852 FTL/B2M/GLRX3/SRI/SLC40A1/ATP6AP1/TFRC 7 GO:0048146 positive regulation of fibroblast proliferation 5/566 48/18722 0.0145722070943001 0.101066915888736 FN1/CD74/MIF/CCNB1/CCNA2 5 GO:0090199 regulation of release of cytochrome c from mitochondria 5/566 48/18722 0.0145722070943001 0.101066915888736 GPX1/TRIAP1/GHITM/PDCD5/BNIP3 5 GO:0014015 positive regulation of gliogenesis 6/566 66/18722 0.014597041086356 0.101066915888736 LRP2/IL6ST/SERPINE2/EGFR/SPINT1/DAG1 6 GO:0051893 regulation of focal adhesion assembly 6/566 66/18722 0.014597041086356 0.101066915888736 ACTG1/LRP1/S100A10/NRP1/IQGAP1/MACF1 6 GO:0090109 regulation of cell-substrate junction assembly 6/566 66/18722 0.014597041086356 0.101066915888736 ACTG1/LRP1/S100A10/NRP1/IQGAP1/MACF1 6 GO:0002793 positive regulation of peptide secretion 8/566 106/18722 0.0150834614905295 0.103789135325869 DYNLL1/HLA-DRB1/LRP1/EGFR/ISL1/PHPT1/SRI/GJA1 8 GO:0006090 pyruvate metabolic process 8/566 106/18722 0.0150834614905295 0.103789135325869 GAPDH/LDHA/TPI1/ALDOA/ENO1/VDAC1/PKM/APP 8 GO:0006766 vitamin metabolic process 8/566 106/18722 0.0150834614905295 0.103789135325869 LRP2/SLC2A1/LGMN/SLC19A1/SLC52A1/MTHFS/GSTO1/FOLR1 8 GO:0042116 macrophage activation 8/566 106/18722 0.0150834614905295 0.103789135325869 CD74/MIF/HMGB1/TYROBP/HSPD1/GRN/APP/AIF1 8 GO:0007435 salivary gland morphogenesis 4/566 32/18722 0.0151955032348189 0.104077508309867 LAMA5/PLXNA1/NRP1/DAG1 4 GO:0048841 regulation of axon extension involved in axon guidance 4/566 32/18722 0.0151955032348189 0.104077508309867 SEMA6D/SEMA3F/NRP1/SEMA6A 4 GO:0050685 positive regulation of mRNA processing 4/566 32/18722 0.0151955032348189 0.104077508309867 NCL/CCNB1/CIRBP/DAZAP1 4 GO:0060047 heart contraction 14/566 241/18722 0.0152362216450983 0.10419609641164 CALM1/ATP2B4/ISL1/GPX1/AKAP9/GSTO1/DSC2/GLRX3/GAA/SRI/GJA1/ATP2B1/DSG2/ADRB1 14 GO:0035023 regulation of Rho protein signal transduction 7/566 86/18722 0.0153058265114282 0.104351515511299 APOE/STMN1/ADGRG1/MET/NRP1/ITGB1/ABCA1 7 GO:2001251 negative regulation of chromosome organization 7/566 86/18722 0.0153058265114282 0.104351515511299 HNRNPA1/MAD2L1/HNRNPC/CCNB1/BUB3/PTTG1/ZWINT 7 GO:0061564 axon development 23/566 467/18722 0.0154717920747091 0.105321740545267 FN1/APOE/SPP1/LAMA5/HSP90AB1/RPL24/LRP1/STMN1/PTPRF/ISL1/PLXNA1/SEMA6D/SEMA3F/PLXNB1/NRP1/ITGB1/GRN/DAG1/APP/MACF1/PLXNB2/FOLR1/SEMA6A 23 GO:0071103 DNA conformation change 16/566 290/18722 0.0155578079855286 0.105745589544387 NPM1/HMGB2/HMGB1/ANXA1/HMGB3/DNAJC9/CCNB1/BANF1/CDK1/RFC2/ITGB3BP/HAT1/HNRNPA2B1/RFC3/RAD51/RUVBL1 16 GO:0006879 cellular iron ion homeostasis 6/566 67/18722 0.0156362362563866 0.106116652154623 FTL/GLRX3/SRI/SLC40A1/ATP6AP1/TFRC 6 GO:0002790 peptide secretion 14/566 242/18722 0.0157409465867099 0.106661285766098 CD74/DYNLL1/HLA-DRB1/ANXA1/LRP1/EGFR/ISL1/PHPT1/PARK7/ABCA1/DPP4/LRP5/SRI/GJA1 14 GO:0001913 T cell mediated cytotoxicity 5/566 49/18722 0.015836278052873 0.106661285766098 HLA-B/HLA-DRB1/HLA-A/HLA-DRA/B2M 5 GO:0018198 peptidyl-cysteine modification 5/566 49/18722 0.015836278052873 0.106661285766098 GAPDH/ATP2B4/PRDX3/PARK7/TXN 5 GO:0070849 response to epidermal growth factor 5/566 49/18722 0.015836278052873 0.106661285766098 EEF1A1/GSTP1/NCL/EGFR/IQGAP1 5 GO:0072091 regulation of stem cell proliferation 5/566 49/18722 0.015836278052873 0.106661285766098 HMGB2/CCNE1/FBLN1/GJA1/PDCD2 5 GO:0005976 polysaccharide metabolic process 8/566 107/18722 0.015886375202181 0.106675931221885 HMGB1/IL6ST/PTGES3/PPP1CA/UGP2/IGF2/GAA/B3GNT3 8 GO:0008637 apoptotic mitochondrial changes 8/566 107/18722 0.015886375202181 0.106675931221885 VDAC2/SLC25A5/GPX1/TRIAP1/HSPD1/GHITM/PDCD5/BNIP3 8 GO:0002283 neutrophil activation involved in immune response 3/566 18/18722 0.0159892421139547 0.10672279743827 TYROBP/FCER1G/ANXA3 3 GO:0006595 polyamine metabolic process 3/566 18/18722 0.0159892421139547 0.10672279743827 AOC1/OAZ1/SMS 3 GO:0044247 cellular polysaccharide catabolic process 3/566 18/18722 0.0159892421139547 0.10672279743827 HMGB1/PPP1CA/GAA 3 GO:0051382 kinetochore assembly 3/566 18/18722 0.0159892421139547 0.10672279743827 CENPK/CENPN/CENPH 3 GO:0006022 aminoglycan metabolic process 9/566 129/18722 0.0165177870899183 0.110085610964545 CHPF/GNS/ITIH5/HEXB/NAGLU/HS6ST2/GLB1/B3GNT3/HEXA 9 GO:0031503 protein-containing complex localization 13/566 220/18722 0.0166778505991813 0.11082058338441 NPM1/SRSF3/RAN/TYROBP/ALYREF/SSB/BIRC5/HNRNPA2B1/DAG1/AKAP9/THOC6/CLSTN1/SMG1 13 GO:0097529 myeloid leukocyte migration 13/566 220/18722 0.0166778505991813 0.11082058338441 CD74/MIF/HMGB1/FLT1/CSF3R/FCER1G/ANXA1/PPIA/RPS19/LGMN/AIF1/DPP4/SERPINE1 13 GO:0006753 nucleoside phosphate metabolic process 24/566 497/18722 0.0168541170229467 0.111388460709297 GAPDH/LDHA/RAN/TPI1/ALDOA/ENO1/TYMS/PKM/NME1/SLC26A2/DUT/IMPDH2/PARK7/TK1/RRM2/TMSB4X/UMPS/STOML2/APP/DNPH1/GMPS/GNAI3/NUDT15/NME2 24 GO:0031116 positive regulation of microtubule polymerization 4/566 33/18722 0.0168884121695363 0.111388460709297 RPS3/MET/AKAP9/CLIP1 4 GO:0042558 pteridine-containing compound metabolic process 4/566 33/18722 0.0168884121695363 0.111388460709297 TYMS/SLC19A1/MTHFS/FOLR1 4 GO:0046685 response to arsenic-containing substance 4/566 33/18722 0.0168884121695363 0.111388460709297 HNRNPA1/SLC38A2/GSTO1/SERPINF1 4 GO:0070570 regulation of neuron projection regeneration 4/566 33/18722 0.0168884121695363 0.111388460709297 SPP1/LRP1/PTPRF/GRN 4 GO:0071692 protein localization to extracellular region 19/566 368/18722 0.0169627477455862 0.111713244028624 FBN2/FBN1/APOE/DYNLL1/HLA-DRB1/ANXA1/PPIA/LRP1/EGFR/ISL1/PHPT1/PARK7/ABCA1/DPP4/LRP5/SRI/GJA1/CANX/P3H1 19 GO:0006220 pyrimidine nucleotide metabolic process 5/566 50/18722 0.0171713581826885 0.112920068876409 TYMS/NME1/DUT/UMPS/NME2 5 GO:0050867 positive regulation of cell activation 21/566 420/18722 0.0173050713329809 0.113631530345768 RPS3/CD74/MIF/LGALS1/HMGB1/HLA-DRB1/TYROBP/HLA-DPA1/HLA-A/ANXA1/HLA-DRA/HLA-DPB1/IL6ST/B2M/HSPD1/CD46/AIF1/DPP4/IGF2/SLC39A10/TFRC 21 GO:0002456 T cell mediated immunity 8/566 109/18722 0.0175841494063604 0.115294010540672 HLA-B/HMGB1/HLA-DRB1/HLA-A/HLA-DRA/B2M/HSPD1/CD46 8 GO:0031667 response to nutrient levels 23/566 474/18722 0.0180983167958034 0.118490744668995 LDHA/APOE/SPP1/HNRNPA1/AOC1/TYMS/CYBA/GSTP1/EGFR/SLC2A1/SPARC/SLC6A4/COX4I1/HAT1/SLC38A2/GABARAP/ABCA1/BNIP3/KRT18/ATP2B1/FOLR1/EIF2A/ADRB1 23 GO:0007088 regulation of mitotic nuclear division 8/566 110/18722 0.0184801883173523 0.120272282097701 MAD2L1/CCNB1/BUB3/ZWINT/ANAPC11/IGF2/LRP5/MKI67 8 GO:0051258 protein polymerization 16/566 296/18722 0.0184995903308252 0.120272282097701 RPS3/PFN1/VDAC2/STMN1/TMSB10/ARPC2/ARPC5/MET/TMSB4X/ARPC1A/UBE2S/AKAP9/AIF1/SCIN/TUBGCP2/CLIP1 16 GO:0002281 macrophage activation involved in immune response 3/566 19/18722 0.0185689015902079 0.120272282097701 HMGB1/TYROBP/GRN 3 GO:0009148 pyrimidine nucleoside triphosphate biosynthetic process 3/566 19/18722 0.0185689015902079 0.120272282097701 TYMS/NME1/NME2 3 GO:0031290 retinal ganglion cell axon guidance 3/566 19/18722 0.0185689015902079 0.120272282097701 RPL24/ISL1/NRP1 3 GO:0035461 vitamin transmembrane transport 3/566 19/18722 0.0185689015902079 0.120272282097701 LRP2/SLC19A1/FOLR1 3 GO:0001662 behavioral fear response 4/566 34/18722 0.0186946134796965 0.120272282097701 APOE/VDAC1/DPP4/GJA1 4 GO:0007431 salivary gland development 4/566 34/18722 0.0186946134796965 0.120272282097701 LAMA5/PLXNA1/NRP1/DAG1 4 GO:0051085 chaperone cofactor-dependent protein refolding 4/566 34/18722 0.0186946134796965 0.120272282097701 CD74/PTGES3/HSPA9/HSPE1 4 GO:0055094 response to lipoprotein particle 4/566 34/18722 0.0186946134796965 0.120272282097701 APOE/FCER1G/ITGB1/ABCA1 4 GO:0086004 regulation of cardiac muscle cell contraction 4/566 34/18722 0.0186946134796965 0.120272282097701 AKAP9/DSC2/SRI/DSG2 4 GO:1990000 amyloid fibril formation 4/566 34/18722 0.0186946134796965 0.120272282097701 APOE/B2M/APP/PFDN4 4 GO:0048872 homeostasis of number of cells 15/566 272/18722 0.0188412835505191 0.121040973112426 RPS6/CD74/RPS17/HMGB2/HMGB1/ANXA1/PRDX1/SLC25A5/FSTL1/RPS19/B2M/ADGRG1/HSPA9/CCNB2/FH 15 GO:0046031 ADP metabolic process 7/566 90/18722 0.0192215300278602 0.123305838161432 GAPDH/LDHA/TPI1/ALDOA/ENO1/PKM/APP 7 GO:0065004 protein-DNA complex assembly 12/566 201/18722 0.0194953849668781 0.124882667442505 NPM1/HMGB2/HMGB1/DNAJC9/CENPK/CENPN/ITGB3BP/GMNN/HAT1/RAD51/PIH1D1/CENPH 12 GO:0045926 negative regulation of growth 14/566 249/18722 0.0196411409019164 0.125599632110025 SPP1/ENO1/SERPINE2/LGMN/SLC6A4/SEMA6D/MT2A/SEMA3F/CGA/NRP1/NDUFS3/GJA1/ADRB1/SEMA6A 14 GO:0008037 cell recognition 13/566 225/18722 0.0196919459148242 0.125599632110025 ALDOA/VDAC2/CCT8/CCT5/CCT7/CCT3/TCP1/CCT2/NRP1/B4GALT1/COLEC12/APP/FOLR1 13 GO:0010001 glial cell differentiation 13/566 225/18722 0.0196919459148242 0.125599632110025 VIM/LRP1/IL6ST/SERPINE2/GSTP1/EGFR/CDK1/SPINT1/GRN/DAG1/ITGB4/BNIP3/APP 13 GO:0046887 positive regulation of hormone secretion 9/566 133/18722 0.0197603466566441 0.125855598448326 SPP1/DYNLL1/HLA-DRB1/LRP1/EGFR/ISL1/PHPT1/SRI/GJA1 9 GO:0043277 apoptotic cell clearance 5/566 52/18722 0.0200604065919034 0.127584185924506 HMGB1/TYROBP/ANXA1/LRP1/ITGAV 5 GO:0000819 sister chromatid segregation 12/566 202/18722 0.0201811268839761 0.128168868598376 RAN/MAD2L1/CCNB1/NUDC/BUB3/CHMP5/CENPK/PTTG1/ZWINT/CDC20/ANAPC11/CDC26 12 GO:0150116 regulation of cell-substrate junction organization 6/566 71/18722 0.0203044102607013 0.128768140285815 ACTG1/LRP1/S100A10/NRP1/IQGAP1/MACF1 6 GO:0043254 regulation of protein-containing complex assembly 21/566 427/18722 0.0203644105285235 0.128813641108847 RPS3/PFN1/APOE/RPL13A/HMGB1/VDAC2/STMN1/TMSB10/ISL1/PARK7/ARPC2/ARPC5/MET/TMSB4X/ARPC1A/AKAP9/ABCA1/SCIN/PIH1D1/CLIP1/TFRC 21 GO:0002821 positive regulation of adaptive immune response 8/566 112/18722 0.0203694526820818 0.128813641108847 HLA-B/HLA-DRB1/HLA-A/HLA-DRA/IL6ST/B2M/HSPD1/TFRC 8 GO:0002209 behavioral defense response 4/566 35/18722 0.0206160344505986 0.12959242874762 APOE/VDAC1/DPP4/GJA1 4 GO:0035633 maintenance of blood-brain barrier 4/566 35/18722 0.0206160344505986 0.12959242874762 ACTG1/LAMC1/ITGB1/GJA1 4 GO:0045454 cell redox homeostasis 4/566 35/18722 0.0206160344505986 0.12959242874762 PRDX1/PRDX3/GPX1/TXN 4 GO:0097421 liver regeneration 4/566 35/18722 0.0206160344505986 0.12959242874762 RPS16/TYMS/EGFR/RPL19 4 GO:0061041 regulation of wound healing 9/566 134/18722 0.0206381473454767 0.12959242874762 APOE/HMGB1/ACTG1/ANXA1/SERPINE2/ITGB1/PLPP3/GJA1/SERPINE1 9 GO:0003015 heart process 14/566 251/18722 0.0208793271251953 0.130836512068379 CALM1/ATP2B4/ISL1/GPX1/AKAP9/GSTO1/DSC2/GLRX3/GAA/SRI/GJA1/ATP2B1/DSG2/ADRB1 14 GO:0007411 axon guidance 13/566 227/18722 0.0210057689321586 0.130836512068379 LAMA5/RPL24/LRP1/ISL1/PLXNA1/SEMA6D/SEMA3F/PLXNB1/NRP1/DAG1/APP/PLXNB2/SEMA6A 13 GO:0002262 myeloid cell homeostasis 10/566 157/18722 0.0211631236422634 0.130836512068379 RPS6/RPS17/HMGB2/HMGB1/ANXA1/PRDX1/SLC25A5/RPS19/B2M/HSPA9 10 GO:0000272 polysaccharide catabolic process 3/566 20/18722 0.0213652615170062 0.130836512068379 HMGB1/PPP1CA/GAA 3 GO:0002834 regulation of response to tumor cell 3/566 20/18722 0.0213652615170062 0.130836512068379 HMGB1/HLA-DRB1/HSPD1 3 GO:0002837 regulation of immune response to tumor cell 3/566 20/18722 0.0213652615170062 0.130836512068379 HMGB1/HLA-DRB1/HSPD1 3 GO:0009129 pyrimidine nucleoside monophosphate metabolic process 3/566 20/18722 0.0213652615170062 0.130836512068379 TYMS/DUT/UMPS 3 GO:0010523 negative regulation of calcium ion transport into cytosol 3/566 20/18722 0.0213652615170062 0.130836512068379 CALM1/GSTO1/SRI 3 GO:0048025 negative regulation of mRNA splicing, via spliceosome 3/566 20/18722 0.0213652615170062 0.130836512068379 NPM1/SRSF7/SRSF9 3 GO:0071243 cellular response to arsenic-containing substance 3/566 20/18722 0.0213652615170062 0.130836512068379 HNRNPA1/SLC38A2/GSTO1 3 GO:0071731 response to nitric oxide 3/566 20/18722 0.0213652615170062 0.130836512068379 TXN/HNRNPD/CCNA2 3 GO:0072567 chemokine (C-X-C motif) ligand 2 production 3/566 20/18722 0.0213652615170062 0.130836512068379 CD74/HMGB1/LRP1 3 GO:0090201 negative regulation of release of cytochrome c from mitochondria 3/566 20/18722 0.0213652615170062 0.130836512068379 GPX1/TRIAP1/GHITM 3 GO:0098543 detection of other organism 3/566 20/18722 0.0213652615170062 0.130836512068379 HLA-B/HLA-DRB1/HLA-A 3 GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway 3/566 20/18722 0.0213652615170062 0.130836512068379 PPIA/GPX1/PARK7 3 GO:1903206 negative regulation of hydrogen peroxide-induced cell death 3/566 20/18722 0.0213652615170062 0.130836512068379 PARK7/TXN/MET 3 GO:2000341 regulation of chemokine (C-X-C motif) ligand 2 production 3/566 20/18722 0.0213652615170062 0.130836512068379 CD74/HMGB1/LRP1 3 GO:2000678 negative regulation of transcription regulatory region DNA binding 3/566 20/18722 0.0213652615170062 0.130836512068379 TMSB4X/ZNF593/SRI 3 GO:0030330 DNA damage response, signal transduction by p53 class mediator 6/566 72/18722 0.0216043591393693 0.131654424578066 NPM1/CD74/RPL26/MIF/EEF1E1/TRIAP1 6 GO:0043903 regulation of biological process involved in symbiotic interaction 6/566 72/18722 0.0216043591393693 0.131654424578066 CD74/LGALS1/HLA-DRB1/IFITM2/ITGAV/P4HB 6 GO:0071383 cellular response to steroid hormone stimulus 12/566 204/18722 0.021606262559013 0.131654424578066 ANXA1/DNAJA1/UBE2L3/GSTP1/EGFR/PTGES3/ISL1/PARK7/SERPINF1/PAQR7/ATP2B1/CALR 12 GO:1903202 negative regulation of oxidative stress-induced cell death 5/566 53/18722 0.021617112391412 0.131654424578066 PPIA/GPX1/PARK7/TXN/MET 5 GO:0097485 neuron projection guidance 13/566 228/18722 0.021686749836449 0.131898101464305 LAMA5/RPL24/LRP1/ISL1/PLXNA1/SEMA6D/SEMA3F/PLXNB1/NRP1/DAG1/APP/PLXNB2/SEMA6A 13 GO:0008361 regulation of cell size 11/566 181/18722 0.0219764913820477 0.133114747799832 FN1/NPM1/APOE/SPP1/HSP90AB1/LRP1/SEMA6D/SEMA3F/NRP1/MACF1/SEMA6A 11 GO:0045766 positive regulation of angiogenesis 11/566 181/18722 0.0219764913820477 0.133114747799832 HMGB1/FLT1/PKM/ISL1/ANXA3/ITGB8/NRP1/ITGB1/ENG/GRN/SERPINE1 11 GO:1904018 positive regulation of vasculature development 11/566 181/18722 0.0219764913820477 0.133114747799832 HMGB1/FLT1/PKM/ISL1/ANXA3/ITGB8/NRP1/ITGB1/ENG/GRN/SERPINE1 11 GO:0001649 osteoblast differentiation 13/566 229/18722 0.0223840693565145 0.135024677703438 FBN2/SPP1/CRIM1/IL6ST/HNRNPC/ALYREF/RRBP1/HSPE1/RSL1D1/GPNMB/IGF2/LRP5/ATP6AP1 13 GO:0002286 T cell activation involved in immune response 8/566 114/18722 0.02239203426726 0.135024677703438 RPS6/CD74/HMGB1/HLA-DRB1/FCER1G/ANXA1/HLA-DRA/CD46 8 GO:1901800 positive regulation of proteasomal protein catabolic process 8/566 114/18722 0.02239203426726 0.135024677703438 SUMO2/DDA1/BAG2/GABARAP/CDC20/PSMC4/UBE2V2/TMEM259 8 GO:0031349 positive regulation of defense response 15/566 278/18722 0.0224131259709885 0.135024677703438 NEAT1/HMGB2/HMGB1/TYROBP/IL6ST/CYBA/EGFR/RPS19/PARK7/HSPD1/GRN/APP/GJA1/SERPINE1/MNDA 15 GO:0033273 response to vitamin 7/566 93/18722 0.0225838227158327 0.135378959863605 SPP1/TYMS/GSTP1/EGFR/SPARC/ATP2B1/FOLR1 7 GO:1901992 positive regulation of mitotic cell cycle phase transition 7/566 93/18722 0.0225838227158327 0.135378959863605 ANXA1/CCNB1/EGFR/CDK1/ANAPC11/APP/AIF1 7 GO:0042119 neutrophil activation 4/566 36/18722 0.0226543856914613 0.135378959863605 TYROBP/FCER1G/ANXA3/GRN 4 GO:0046466 membrane lipid catabolic process 4/566 36/18722 0.0226543856914613 0.135378959863605 HEXB/ASAH1/HEXA/GM2A 4 GO:0051385 response to mineralocorticoid 4/566 36/18722 0.0226543856914613 0.135378959863605 CALM1/CYBA/RPL27/ATP2B1 4 GO:0071402 cellular response to lipoprotein particle stimulus 4/566 36/18722 0.0226543856914613 0.135378959863605 APOE/FCER1G/ITGB1/ABCA1 4 GO:0035773 insulin secretion involved in cellular response to glucose stimulus 6/566 73/18722 0.0229593728767049 0.13683417409249 DYNLL1/HLA-DRB1/LRP1/PHPT1/LRP5/SRI 6 GO:0072089 stem cell proliferation 6/566 73/18722 0.0229593728767049 0.13683417409249 HMGB2/CCNE1/FBLN1/GJA1/PDCD2/ZNRF3 6 GO:0048880 sensory system development 19/566 381/18722 0.0233538819381102 0.138999308005972 FBN2/FBN1/VIM/HMGB1/FLT1/ATP2B4/RPL24/HMGN1/COL4A1/ISL1/IMPDH2/TENM3/NRP1/EFEMP1/TUG1/SERPINF1/LRP5/NAGLU/ATP2B1 19 GO:0045471 response to ethanol 9/566 137/18722 0.0234398484722027 0.13904160040268 RPL15/EEF1B2/RPL10A/TYMS/GSTP1/SPARC/CDK1/HPGD/PSMD14 9 GO:0050714 positive regulation of protein secretion 9/566 137/18722 0.0234398484722027 0.13904160040268 DYNLL1/HLA-DRB1/PPIA/LRP1/EGFR/ISL1/PHPT1/SRI/GJA1 9 GO:1901989 positive regulation of cell cycle phase transition 8/566 115/18722 0.0234546814695447 0.13904160040268 NPM1/ANXA1/CCNB1/EGFR/CDK1/ANAPC11/APP/AIF1 8 GO:0002819 regulation of adaptive immune response 11/566 183/18722 0.0236029794393785 0.13973466019164 HLA-B/HMGB1/HLA-DRB1/HLA-A/ANXA1/HLA-DRA/IL6ST/B2M/HSPD1/CD46/TFRC 11 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity 7/566 94/18722 0.0237894540300264 0.140495567647527 CKS1B/CCNB1/EGFR/CCNE1/CKS2/CCNB2/CCNA2 7 GO:0002683 negative regulation of immune system process 21/566 434/18722 0.0238278295882404 0.140495567647527 FBN1/CD74/MIF/HLA-B/HMGB1/HLA-DRB1/TYROBP/HLA-A/ANXA1/NME1/PHPT1/RPS19/GPX1/HSPA9/GRN/CD46/DPP4/GPNMB/NME2/MNDA/HTRA1 21 GO:0045732 positive regulation of protein catabolic process 13/566 231/18722 0.0238285933390545 0.140495567647527 LRP2/APOE/LRP1/OAZ1/SUMO2/DDA1/BAG2/GABARAP/CDC20/PSMC4/GJA1/UBE2V2/TMEM259 13 GO:0042110 T cell activation 23/566 487/18722 0.0238941558709283 0.140495567647527 RPS6/RPS3/CD74/LGALS1/HMGB1/HLA-DRB1/FCER1G/HLA-DPA1/HLA-A/ANXA1/HLA-DRA/HLA-DPB1/IL6ST/B2M/HSPD1/STOML2/CD46/AIF1/DPP4/GPNMB/IGF2/TFRC/CLPTM1 23 GO:0032535 regulation of cellular component size 19/566 382/18722 0.0239126773390581 0.140495567647527 FN1/NPM1/PFN1/APOE/SPP1/HSP90AB1/LRP1/TMSB10/PPP1CA/SEMA6D/ARPC2/ARPC5/SEMA3F/TMSB4X/NRP1/ARPC1A/MACF1/SCIN/SEMA6A 19 GO:0001503 ossification 20/566 408/18722 0.0239208536111468 0.140495567647527 FBN2/SPP1/CRIM1/IL6ST/SRGN/HNRNPC/EGFR/ALYREF/SPARC/SLC26A2/RRBP1/RPL38/PLXNB1/HSPE1/RSL1D1/GPNMB/IGF2/LRP5/ATP2B1/ATP6AP1 20 GO:1901293 nucleoside phosphate biosynthetic process 14/566 256/18722 0.0242313283174052 0.141320820320154 ALDOA/ENO1/TYMS/NME1/SLC26A2/DUT/IMPDH2/TK1/RRM2/TMSB4X/UMPS/STOML2/GMPS/NME2 14 GO:1903522 regulation of blood circulation 14/566 256/18722 0.0242313283174052 0.141320820320154 CALM1/ATP2B4/EGFR/ISL1/AKAP9/GSTO1/DSC2/GLRX3/GAA/SRI/GJA1/ATP2B1/DSG2/ADRB1 14 GO:0006801 superoxide metabolic process 6/566 74/18722 0.024370339223355 0.141320820320154 TYROBP/PRDX1/CYBA/GSTP1/EGFR/GNAI3 6 GO:0007040 lysosome organization 6/566 74/18722 0.024370339223355 0.141320820320154 CHMP5/GRN/ABCA1/GAA/HEXB/NAGLU 6 GO:0080171 lytic vacuole organization 6/566 74/18722 0.024370339223355 0.141320820320154 CHMP5/GRN/ABCA1/GAA/HEXB/NAGLU 6 GO:1903201 regulation of oxidative stress-induced cell death 6/566 74/18722 0.024370339223355 0.141320820320154 PPIA/GPX1/PARK7/TXN/MET/P4HB 6 GO:0032516 positive regulation of phosphoprotein phosphatase activity 3/566 21/18722 0.0243787938018595 0.141320820320154 CALM1/HSP90AB1/SLC39A10 3 GO:0038083 peptidyl-tyrosine autophosphorylation 3/566 21/18722 0.0243787938018595 0.141320820320154 EGFR/IQGAP1/IGF1R 3 GO:0045056 transcytosis 3/566 21/18722 0.0243787938018595 0.141320820320154 LRP2/LRP1/IGF1R 3 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 3/566 21/18722 0.0243787938018595 0.141320820320154 CD74/MIF/TRIAP1 3 GO:0032273 positive regulation of protein polymerization 9/566 138/18722 0.0244312835508556 0.141440928957619 RPS3/PFN1/ARPC2/ARPC5/MET/ARPC1A/AKAP9/SCIN/CLIP1 9 GO:0021782 glial cell development 8/566 116/18722 0.0245522710493893 0.141910985754873 VIM/LRP1/GSTP1/EGFR/GRN/DAG1/ITGB4/APP 8 GO:0032271 regulation of protein polymerization 13/566 232/18722 0.0245762286650959 0.141910985754873 RPS3/PFN1/VDAC2/STMN1/TMSB10/ARPC2/ARPC5/MET/TMSB4X/ARPC1A/AKAP9/SCIN/CLIP1 13 GO:0031112 positive regulation of microtubule polymerization or depolymerization 4/566 37/18722 0.0248111629319464 0.14234445537761 RPS3/MET/AKAP9/CLIP1 4 GO:0033120 positive regulation of RNA splicing 4/566 37/18722 0.0248111629319464 0.14234445537761 NCL/CIRBP/SLC38A2/DAZAP1 4 GO:0033363 secretory granule organization 4/566 37/18722 0.0248111629319464 0.14234445537761 SERPINE2/SRGN/ABCA1/RAB38 4 GO:0048846 axon extension involved in axon guidance 4/566 37/18722 0.0248111629319464 0.14234445537761 SEMA6D/SEMA3F/NRP1/SEMA6A 4 GO:1902284 neuron projection extension involved in neuron projection guidance 4/566 37/18722 0.0248111629319464 0.14234445537761 SEMA6D/SEMA3F/NRP1/SEMA6A 4 GO:0009117 nucleotide metabolic process 23/566 489/18722 0.024900334960022 0.142672189500666 GAPDH/LDHA/RAN/TPI1/ALDOA/ENO1/TYMS/PKM/NME1/SLC26A2/DUT/IMPDH2/PARK7/RRM2/TMSB4X/UMPS/STOML2/APP/DNPH1/GMPS/GNAI3/NUDT15/NME2 23 GO:0031113 regulation of microtubule polymerization 5/566 55/18722 0.0249611342225934 0.142836721798183 RPS3/STMN1/MET/AKAP9/CLIP1 5 GO:0036473 cell death in response to oxidative stress 7/566 95/18722 0.0250386414143156 0.143096317813264 PPIA/GPX1/PARK7/TXN/MET/PDCD10/P4HB 7 GO:0007160 cell-matrix adhesion 13/566 233/18722 0.0253410641249571 0.144638996774755 FN1/ACTG1/LRP1/BCAM/S100A10/ITGAV/NRP1/ITGB1/DAG1/ITGB4/IQGAP1/MACF1/SERPINE1 13 GO:0051146 striated muscle cell differentiation 15/566 283/18722 0.025760747778061 0.146846157628589 KRT19/YBX1/ACTG1/CSRP2/MORF4L2/CCNB1/ISL1/CACYBP/CDK1/GPX1/KRT8/ITGB1/IGF2/PLD3/CALR 15 GO:0002292 T cell differentiation involved in immune response 6/566 75/18722 0.0258381077578737 0.146910926868523 HMGB1/HLA-DRB1/FCER1G/ANXA1/HLA-DRA/CD46 6 GO:1902369 negative regulation of RNA catabolic process 6/566 75/18722 0.0258381077578737 0.146910926868523 YBX1/YBX3/HNRNPC/HNRNPD/CIRBP/ZCCHC17 6 GO:0043648 dicarboxylic acid metabolic process 7/566 96/18722 0.0263320280094883 0.149337819997761 MDH1/MDH2/SLC19A1/MTHFS/SDHB/FH/FOLR1 7 GO:0051304 chromosome separation 7/566 96/18722 0.0263320280094883 0.149337819997761 MAD2L1/CCNB1/BUB3/PTTG1/ZWINT/ANAPC11/CDC26 7 GO:0072331 signal transduction by p53 class mediator 10/566 163/18722 0.0265960233817903 0.150643124803728 NPM1/CD74/RPL26/RPL5/RPL23/MIF/RPS20/RPL11/EEF1E1/TRIAP1 10 GO:0006687 glycosphingolipid metabolic process 5/566 56/18722 0.0267507043840032 0.150943138045098 ITGB8/HEXB/GLB1/HEXA/GM2A 5 GO:0048255 mRNA stabilization 5/566 56/18722 0.0267507043840032 0.150943138045098 YBX1/YBX3/HNRNPC/HNRNPD/CIRBP 5 GO:1904645 response to amyloid-beta 5/566 56/18722 0.0267507043840032 0.150943138045098 LRP1/LGMN/APP/GJA1/IGF1R 5 GO:0070997 neuron death 18/566 361/18722 0.0268368073366498 0.151237299066791 GAPDH/APOE/HSP90AB1/TYROBP/LRP1/ISL1/LGMN/GPX1/PARK7/HSPD1/NRP1/GRN/BNIP3/APP/SERPINF1/GPNMB/UBE2V2/TMEM259 18 GO:0007094 mitotic spindle assembly checkpoint signaling 4/566 38/18722 0.0270876494741311 0.152073411675702 MAD2L1/CCNB1/BUB3/ZWINT 4 GO:0071173 spindle assembly checkpoint signaling 4/566 38/18722 0.0270876494741311 0.152073411675702 MAD2L1/CCNB1/BUB3/ZWINT 4 GO:0071174 mitotic spindle checkpoint signaling 4/566 38/18722 0.0270876494741311 0.152073411675702 MAD2L1/CCNB1/BUB3/ZWINT 4 GO:0043491 protein kinase B signaling 12/566 211/18722 0.0271840653124799 0.152422492155114 LRP2/HSP90AB1/EGFR/GPX1/PARK7/TXN/MET/ITGB1/ENG/DAG1/IGF2/IGF1R 12 GO:2000379 positive regulation of reactive oxygen species metabolic process 6/566 76/18722 0.0273634888695714 0.1532355376696 TYROBP/CYBA/GSTP1/EGFR/PARK7/GNAI3 6 GO:0050921 positive regulation of chemotaxis 9/566 141/18722 0.027584021049602 0.153262413473539 CD74/HMGB1/LGMN/MET/TMSB4X/NRP1/AIF1/SERPINE1/CALR 9 GO:0009220 pyrimidine ribonucleotide biosynthetic process 3/566 22/18722 0.0276092667578119 0.153262413473539 NME1/UMPS/NME2 3 GO:0035024 negative regulation of Rho protein signal transduction 3/566 22/18722 0.0276092667578119 0.153262413473539 STMN1/MET/ITGB1 3 GO:0048026 positive regulation of mRNA splicing, via spliceosome 3/566 22/18722 0.0276092667578119 0.153262413473539 NCL/CIRBP/DAZAP1 3 GO:0071404 cellular response to low-density lipoprotein particle stimulus 3/566 22/18722 0.0276092667578119 0.153262413473539 FCER1G/ITGB1/ABCA1 3 GO:1900120 regulation of receptor binding 3/566 22/18722 0.0276092667578119 0.153262413473539 PTPRF/B2M/NRP1 3 GO:1901032 negative regulation of response to reactive oxygen species 3/566 22/18722 0.0276092667578119 0.153262413473539 PARK7/TXN/MET 3 GO:0000209 protein polyubiquitination 13/566 236/18722 0.02774087474041 0.153609918338688 PPIA/UBE2L3/UBE2N/UBE2T/UBE2D2/DDA1/AMFR/UBE2S/GABARAP/ANAPC11/CDC26/NHLRC3/UBE2V2 13 GO:0090068 positive regulation of cell cycle process 13/566 236/18722 0.02774087474041 0.153609918338688 NPM1/RANBP1/ANXA1/MAD2L1/CCNB1/EGFR/CDK1/ANAPC11/APP/AIF1/IGF2/LRP5/DBF4 13 GO:0006575 cellular modified amino acid metabolic process 11/566 188/18722 0.0280510161212668 0.155134315244571 TYMS/GSTP1/GPX1/PARK7/CGA/SLC19A1/MTHFS/GSTO1/FOLR1/PCYOX1/CTSB 11 GO:0031334 positive regulation of protein-containing complex assembly 13/566 237/18722 0.028576604513506 0.157844966866165 RPS3/PFN1/PARK7/ARPC2/ARPC5/MET/ARPC1A/AKAP9/ABCA1/SCIN/PIH1D1/CLIP1/TFRC 13 GO:0051205 protein insertion into membrane 5/566 57/18722 0.0286200115933781 0.157888837191722 EGFR/TOMM22/PDCD5/TIMM9/EMC1 5 GO:0050729 positive regulation of inflammatory response 9/566 142/18722 0.0286957471723059 0.158110725756319 NEAT1/IL6ST/EGFR/RPS19/PARK7/HSPD1/GRN/APP/SERPINE1 9 GO:0022411 cellular component disassembly 21/566 443/18722 0.0289250011772204 0.158710799967953 RPL23/CALM1/VDAC1/SLC25A5/LRP1/LAMC1/STMN1/CDK1/PPP1CA/PARK7/CHMP5/CFL1/FUNDC2/SUPT16H/GABARAP/VRK1/BNIP3/DPP4/VPS13C/SCIN/IGF1R 21 GO:0000380 alternative mRNA splicing, via spliceosome 6/566 77/18722 0.0289472528243437 0.158710799967953 HNRNPA1/HNRNPM/SRSF9/MAGOH/RBM8A/RBM17 6 GO:0021675 nerve development 6/566 77/18722 0.0289472528243437 0.158710799967953 RPL24/SERPINE2/ISL1/SEMA3F/NRP1/DAG1 6 GO:0055117 regulation of cardiac muscle contraction 6/566 77/18722 0.0289472528243437 0.158710799967953 CALM1/AKAP9/GSTO1/DSC2/SRI/DSG2 6 GO:0007052 mitotic spindle organization 8/566 120/18722 0.0293021471077399 0.16026186599958 RAN/STMN1/SPC25/CCNB1/NUDC/CHMP5/CDC20/CENPH 8 GO:0072655 establishment of protein localization to mitochondrion 8/566 120/18722 0.0293021471077399 0.16026186599958 CALM1/DNAJA1/UBE2L3/HSPD1/TOMM22/PDCD5/LMAN1/TIMM9 8 GO:0007618 mating 4/566 39/18722 0.0294849192335339 0.16027699685921 SERPINE2/SLC6A4/APP/HEXB 4 GO:0016572 histone phosphorylation 4/566 39/18722 0.0294849192335339 0.16027699685921 CCNB1/CDK1/CCNA2/VRK1 4 GO:0031577 spindle checkpoint signaling 4/566 39/18722 0.0294849192335339 0.16027699685921 MAD2L1/CCNB1/BUB3/ZWINT 4 GO:0086091 regulation of heart rate by cardiac conduction 4/566 39/18722 0.0294849192335339 0.16027699685921 ISL1/AKAP9/DSC2/DSG2 4 GO:1903115 regulation of actin filament-based movement 4/566 39/18722 0.0294849192335339 0.16027699685921 AKAP9/DSC2/SRI/DSG2 4 GO:0062013 positive regulation of small molecule metabolic process 9/566 143/18722 0.0298385274315912 0.161900123519842 CD74/HMGB1/ENO1/ANXA1/PARK7/TMSB4X/APP/IGF2/P2RY6 9 GO:0007409 axonogenesis 20/566 418/18722 0.0298562447012108 0.161900123519842 FN1/APOE/SPP1/LAMA5/HSP90AB1/RPL24/LRP1/STMN1/ISL1/PLXNA1/SEMA6D/SEMA3F/PLXNB1/NRP1/ITGB1/DAG1/APP/MACF1/PLXNB2/SEMA6A 20 GO:0060249 anatomical structure homeostasis 16/566 314/18722 0.0299076599154007 0.161981632534506 LYZ/SPP1/ACTG1/ALDOA/PRDX1/LAMC1/EGFR/SLC2A1/B2M/ITGB1/GAA/FH/GJA1/ATP2B1/ATP6AP1/TFRC 16 GO:0015833 peptide transport 14/566 264/18722 0.0304055070013868 0.16447735980735 CD74/DYNLL1/HLA-DRB1/ANXA1/LRP1/EGFR/ISL1/PHPT1/PARK7/ABCA1/DPP4/LRP5/SRI/GJA1 14 GO:0031341 regulation of cell killing 7/566 99/18722 0.0304834918388606 0.16447735980735 HLA-B/HLA-DRB1/HSP90AB1/TYROBP/HLA-A/HLA-DRA/B2M 7 GO:0042100 B cell proliferation 7/566 99/18722 0.0304834918388606 0.16447735980735 CD74/MIF/TYROBP/HSPD1/SLC39A10/MNDA/TFRC 7 GO:0086065 cell communication involved in cardiac conduction 5/566 58/18722 0.0305699738878106 0.16447735980735 CALM1/DSC2/SRI/GJA1/DSG2 5 GO:0045931 positive regulation of mitotic cell cycle 8/566 121/18722 0.030581907083525 0.16447735980735 ANXA1/CCNB1/EGFR/CDK1/LGMN/ANAPC11/APP/AIF1 8 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 6/566 78/18722 0.0305901289129572 0.16447735980735 PRDX3/BIRC5/GPX1/PARK7/TRIAP1/PIH1D1 6 GO:1903706 regulation of hemopoiesis 18/566 367/18722 0.0308802165562917 0.165779889200425 FBN1/CD74/HLA-B/HMGB2/HMGB1/HLA-DRB1/TYROBP/CSF3R/ANXA1/HLA-DRA/NME1/B2M/HSPA9/CD46/SCIN/NME2/ATP6AP1/CLPTM1 18 GO:0035640 exploration behavior 3/566 23/18722 0.0310558013461713 0.165779889200425 APOE/EIF4A3/DPP4 3 GO:0042026 protein refolding 3/566 23/18722 0.0310558013461713 0.165779889200425 B2M/HSPA9/HSPD1 3 GO:0051383 kinetochore organization 3/566 23/18722 0.0310558013461713 0.165779889200425 CENPK/CENPN/CENPH 3 GO:0060384 innervation 3/566 23/18722 0.0310558013461713 0.165779889200425 SERPINE2/ISL1/NRP1 3 GO:1900273 positive regulation of long-term synaptic potentiation 3/566 23/18722 0.0310558013461713 0.165779889200425 LGMN/APP/MME 3 GO:0045765 regulation of angiogenesis 17/566 342/18722 0.0316067993635797 0.168519126666655 HMGB1/FLT1/COL4A2/ATP2B4/PKM/ISL1/SPARC/ANXA3/ITGB8/NRP1/ITGB1/ENG/GRN/SERPINF1/GPNMB/SERPINE1/SEMA6A 17 GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 10/566 168/18722 0.0318318234768785 0.168905064331796 HLA-B/HMGB1/HLA-DRB1/HLA-A/ANXA1/HLA-DRA/B2M/HSPD1/CD46/TFRC 10 GO:0002688 regulation of leukocyte chemotaxis 8/566 122/18722 0.0318995007511046 0.168905064331796 CD74/MIF/HMGB1/LGMN/AIF1/DPP4/SERPINE1/CALR 8 GO:0009394 2'-deoxyribonucleotide metabolic process 4/566 40/18722 0.0320038403072007 0.168905064331796 TYMS/DUT/DNPH1/NUDT15 4 GO:0010543 regulation of platelet activation 4/566 40/18722 0.0320038403072007 0.168905064331796 APOE/FCER1G/IL6ST/SERPINE2 4 GO:0044275 cellular carbohydrate catabolic process 4/566 40/18722 0.0320038403072007 0.168905064331796 HMGB1/TPI1/PPP1CA/GAA 4 GO:0045841 negative regulation of mitotic metaphase/anaphase transition 4/566 40/18722 0.0320038403072007 0.168905064331796 MAD2L1/CCNB1/BUB3/ZWINT 4 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol 4/566 40/18722 0.0320038403072007 0.168905064331796 CALM1/GSTO1/SRI/P2RY6 4 GO:1901020 negative regulation of calcium ion transmembrane transporter activity 4/566 40/18722 0.0320038403072007 0.168905064331796 CALM1/C4orf3/GSTO1/SRI 4 GO:0032872 regulation of stress-activated MAPK cascade 11/566 192/18722 0.0320206366343297 0.168905064331796 HMGB1/PRDX1/DNAJA1/PPIA/GSTP1/EGFR/PBK/PDCD10/APP/IGF1R/COPS5 11 GO:0044843 cell cycle G1/S phase transition 13/566 241/18722 0.0321038918908925 0.169143818577815 RPS6/RPL26/ANXA1/ATP2B4/EGFR/CCNE1/TRIAP1/CDK2AP2/ITGB1/CCNA2/AIF1/GPNMB/DBF4 13 GO:0006446 regulation of translational initiation 6/566 79/18722 0.0322928046810959 0.16973738658824 NPM1/RPL13A/EIF3E/EIF3H/PPP1CA/EIF1 6 GO:0032272 negative regulation of protein polymerization 6/566 79/18722 0.0322928046810959 0.16973738658824 PFN1/VDAC2/STMN1/TMSB10/TMSB4X/SCIN 6 GO:0001836 release of cytochrome c from mitochondria 5/566 59/18722 0.0326014245217648 0.170353922501053 GPX1/TRIAP1/GHITM/PDCD5/BNIP3 5 GO:0006406 mRNA export from nucleus 5/566 59/18722 0.0326014245217648 0.170353922501053 SRSF3/ALYREF/HNRNPA2B1/THOC6/SMG1 5 GO:0032768 regulation of monooxygenase activity 5/566 59/18722 0.0326014245217648 0.170353922501053 APOE/CALM1/ATP2B4/EGFR/PARK7 5 GO:0051353 positive regulation of oxidoreductase activity 5/566 59/18722 0.0326014245217648 0.170353922501053 APOE/CALM1/CYBA/PARK7/GNAI3 5 GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus 5/566 59/18722 0.0326014245217648 0.170353922501053 SRSF3/ALYREF/HNRNPA2B1/THOC6/SMG1 5 GO:0070374 positive regulation of ERK1 and ERK2 cascade 12/566 217/18722 0.0327426990214223 0.170891554564328 CD74/MIF/APOE/HMGB1/HLA-DRB1/LRP1/EGFR/NRP1/APP/GPNMB/ATP6AP1/P2RY6 12 GO:0032970 regulation of actin filament-based process 19/566 396/18722 0.0328494698056814 0.171248055708306 PFN1/ACTG1/LRP1/STMN1/TMSB10/PHPT1/S100A10/ARPC2/ARPC5/MET/TMSB4X/NRP1/ARPC1A/AKAP9/DSC2/IQGAP1/SRI/SCIN/DSG2 19 GO:0001654 eye development 18/566 371/18722 0.0338172483887176 0.176051010076342 FBN2/FBN1/VIM/HMGB1/FLT1/ATP2B4/RPL24/HMGN1/COL4A1/IMPDH2/TENM3/NRP1/EFEMP1/TUG1/SERPINF1/LRP5/NAGLU/ATP2B1 18 GO:0050708 regulation of protein secretion 14/566 268/18722 0.0338914753735151 0.176051010076342 APOE/DYNLL1/HLA-DRB1/ANXA1/PPIA/LRP1/EGFR/ISL1/PHPT1/DPP4/LRP5/SRI/GJA1/P3H1 14 GO:0048145 regulation of fibroblast proliferation 6/566 80/18722 0.0340559252402979 0.176051010076342 FN1/CD74/MIF/GSTP1/CCNB1/CCNA2 6 GO:0043487 regulation of RNA stability 10/566 170/18722 0.0341161757504251 0.176051010076342 NPM1/YBX1/VIM/YBX3/HNRNPM/HNRNPC/HNRNPD/CIRBP/ZCCHC17/EXOSC9 10 GO:0002285 lymphocyte activation involved in immune response 11/566 194/18722 0.0341483783977228 0.176051010076342 RPS6/CD74/LGALS1/HMGB1/HLA-DRB1/FCER1G/ANXA1/HLA-DRA/HSPD1/CD46/TFRC 11 GO:0051604 protein maturation 15/566 294/18722 0.0344183915297898 0.176051010076342 ENO1/SERPINE2/SRGN/LGMN/HSPD1/GCSH/BAG2/STOML2/GLRX3/NAA20/CPD/GLG1/MME/SERPINE1/CALR 15 GO:0001909 leukocyte mediated cytotoxicity 8/566 124/18722 0.0346499095705781 0.176051010076342 HLA-B/HLA-DRB1/TYROBP/HLA-A/PRDX1/HLA-DRA/TUBB4B/B2M 8 GO:0071496 cellular response to external stimulus 16/566 320/18722 0.0346767766728046 0.176051010076342 HNRNPA1/AOC1/CYBA/GSTP1/EGFR/SLC2A1/SLC38A2/ENG/DAG1/GABARAP/BNIP3/AIF1/GJA1/NUDT15/ATP2B1/FOLR1 16 GO:0042306 regulation of protein import into nucleus 5/566 60/18722 0.0347151116354749 0.176051010076342 RAN/HSP90AB1/NUTF2/CDH1/CDK1 5 GO:0010288 response to lead ion 3/566 24/18722 0.0347169242475058 0.176051010076342 SPARC/PPP1CA/APP 3 GO:0031639 plasminogen activation 3/566 24/18722 0.0347169242475058 0.176051010076342 ENO1/SERPINE2/SERPINE1 3 GO:2001026 regulation of endothelial cell chemotaxis 3/566 24/18722 0.0347169242475058 0.176051010076342 LGMN/MET/TMSB4X 3 GO:0060041 retina development in camera-type eye 9/566 147/18722 0.0347275556622931 0.176051010076342 ATP2B4/RPL24/COL4A1/IMPDH2/NRP1/SERPINF1/LRP5/NAGLU/ATP2B1 9 GO:0000492 box C/D snoRNP assembly 2/566 10/18722 0.0349571188022206 0.176051010076342 RUVBL1/PIH1D1 2 GO:0005984 disaccharide metabolic process 2/566 10/18722 0.0349571188022206 0.176051010076342 B4GALT1/GAA 2 GO:0006012 galactose metabolic process 2/566 10/18722 0.0349571188022206 0.176051010076342 B4GALT1/GLB1 2 GO:0006228 UTP biosynthetic process 2/566 10/18722 0.0349571188022206 0.176051010076342 NME1/NME2 2 GO:0032025 response to cobalt ion 2/566 10/18722 0.0349571188022206 0.176051010076342 BNIP3/SERPINF1 2 GO:0035999 tetrahydrofolate interconversion 2/566 10/18722 0.0349571188022206 0.176051010076342 TYMS/MTHFS 2 GO:0040015 negative regulation of multicellular organism growth 2/566 10/18722 0.0349571188022206 0.176051010076342 LGMN/ADRB1 2 GO:0051409 response to nitrosative stress 2/566 10/18722 0.0349571188022206 0.176051010076342 DNAJA1/PARK7 2 GO:0072378 blood coagulation, fibrin clot formation 2/566 10/18722 0.0349571188022206 0.176051010076342 FN1/FBLN1 2 GO:0090647 modulation of age-related behavioral decline 2/566 10/18722 0.0349571188022206 0.176051010076342 B2M/APP 2 GO:0097250 mitochondrial respirasome assembly 2/566 10/18722 0.0349571188022206 0.176051010076342 COX7A2L/HIGD1A 2 GO:0150172 regulation of phosphatidylcholine metabolic process 2/566 10/18722 0.0349571188022206 0.176051010076342 APOC1/RAB38 2 GO:1901838 positive regulation of transcription of nucleolar large rRNA by RNA polymerase I 2/566 10/18722 0.0349571188022206 0.176051010076342 NCL/PIH1D1 2 GO:1904350 regulation of protein catabolic process in the vacuole 2/566 10/18722 0.0349571188022206 0.176051010076342 LRP2/LRP1 2 GO:1904668 positive regulation of ubiquitin protein ligase activity 2/566 10/18722 0.0349571188022206 0.176051010076342 UBE2S/CDC20 2 GO:2000169 regulation of peptidyl-cysteine S-nitrosylation 2/566 10/18722 0.0349571188022206 0.176051010076342 ATP2B4/TXN 2 GO:2000434 regulation of protein neddylation 2/566 10/18722 0.0349571188022206 0.176051010076342 RPL5/RPL11 2 GO:0030073 insulin secretion 11/566 195/18722 0.0352488685131727 0.177119596637297 DYNLL1/HLA-DRB1/ANXA1/LRP1/ISL1/PHPT1/PARK7/DPP4/LRP5/SRI/GJA1 11 GO:0070302 regulation of stress-activated protein kinase signaling cascade 11/566 195/18722 0.0352488685131727 0.177119596637297 HMGB1/PRDX1/DNAJA1/PPIA/GSTP1/EGFR/PBK/PDCD10/APP/IGF1R/COPS5 11 GO:0050808 synapse organization 20/566 426/18722 0.0353528636867777 0.177441881773996 PFN1/APOE/ACTG1/CDH1/SRGN/COL4A1/PTPRF/SPARC/LGMN/SEMA3F/CFL1/PLXNB1/NRP1/DAG1/CDC20/CLSTN1/APP/PLXNB2/IGF1R/UBE2V2 20 GO:0048144 fibroblast proliferation 6/566 81/18722 0.0358800926587573 0.179885329410797 FN1/CD74/MIF/GSTP1/CCNB1/CCNA2 6 GO:0098656 anion transmembrane transport 13/566 245/18722 0.0359355501226189 0.179921607497461 LRP2/VDAC2/VDAC1/SLC25A5/SLC26A2/SLC19A1/ITGB1/SLC43A2/GJA1/FOLR1/SLC13A4/PCYOX1/SLC1A5 13 GO:0014074 response to purine-containing compound 9/566 148/18722 0.0360310475978804 0.179921607497461 LDHA/NME1/SPARC/SLC6A4/HSPD1/AKAP9/APP/HSP90B1/P2RY6 9 GO:2001056 positive regulation of cysteine-type endopeptidase activity 9/566 148/18722 0.0360310475978804 0.179921607497461 RPS3/HMGB1/CYCS/LGMN/HSPD1/HSPE1/PDCD5/CTSD/PDCD2 9 GO:0070585 protein localization to mitochondrion 8/566 125/18722 0.0360835474622445 0.179921607497461 CALM1/DNAJA1/UBE2L3/HSPD1/TOMM22/PDCD5/LMAN1/TIMM9 8 GO:0031331 positive regulation of cellular catabolic process 20/566 427/18722 0.0360893970115077 0.179921607497461 LRP2/APOE/HMGB1/VDAC1/SLC25A5/LRP1/SUMO2/PARK7/DDA1/HNRNPD/BAG2/GABARAP/CDC20/PSMC4/BNIP3/APP/GNAI3/UBE2V2/TMEM259/EXOSC9 20 GO:1901342 regulation of vasculature development 17/566 348/18722 0.0363548927112938 0.180982771727089 HMGB1/FLT1/COL4A2/ATP2B4/PKM/ISL1/SPARC/ANXA3/ITGB8/NRP1/ITGB1/ENG/GRN/SERPINF1/GPNMB/SERPINE1/SEMA6A 17 GO:0043010 camera-type eye development 16/566 322/18722 0.0363835536153963 0.180982771727089 FBN2/FBN1/VIM/FLT1/ATP2B4/RPL24/HMGN1/COL4A1/IMPDH2/TENM3/NRP1/EFEMP1/SERPINF1/LRP5/NAGLU/ATP2B1 16 GO:1901136 carbohydrate derivative catabolic process 10/566 172/18722 0.0365126833463111 0.181206352437843 DUT/GNS/HEXB/DNPH1/NAGLU/NUDT15/GLB1/EDEM3/HEXA/GM2A 10 GO:0002027 regulation of heart rate 7/566 103/18722 0.0366727141838491 0.181206352437843 CALM1/ISL1/AKAP9/DSC2/SRI/DSG2/ADRB1 7 GO:0009135 purine nucleoside diphosphate metabolic process 7/566 103/18722 0.0366727141838491 0.181206352437843 GAPDH/LDHA/TPI1/ALDOA/ENO1/PKM/APP 7 GO:0009179 purine ribonucleoside diphosphate metabolic process 7/566 103/18722 0.0366727141838491 0.181206352437843 GAPDH/LDHA/TPI1/ALDOA/ENO1/PKM/APP 7 GO:0032760 positive regulation of tumor necrosis factor production 7/566 103/18722 0.0366727141838491 0.181206352437843 MIF/HMGB1/TYROBP/CYBA/ISL1/HSPD1/APP 7 GO:0045639 positive regulation of myeloid cell differentiation 7/566 103/18722 0.0366727141838491 0.181206352437843 CD74/HMGB2/HMGB1/HLA-DRB1/TYROBP/SCIN/ATP6AP1 7 GO:0090342 regulation of cell aging 5/566 61/18722 0.0369116981163259 0.182185011101866 MIF/YBX1/EEF1E1/B2M/RSL1D1 5 GO:0150063 visual system development 18/566 375/18722 0.0369557466958823 0.182200425570396 FBN2/FBN1/VIM/HMGB1/FLT1/ATP2B4/RPL24/HMGN1/COL4A1/IMPDH2/TENM3/NRP1/EFEMP1/TUG1/SERPINF1/LRP5/NAGLU/ATP2B1 18 GO:0009411 response to UV 9/566 149/18722 0.037367701792728 0.183016848887462 NPM1/RPL26/HMGN1/EGFR/GPX1/TRIAP1/CIRBP/PBK/MME 9 GO:1905039 carboxylic acid transmembrane transport 9/566 149/18722 0.037367701792728 0.183016848887462 LRP2/SLC2A1/SLC19A1/SLC38A2/ITGB1/SLC38A10/SLC43A2/FOLR1/SLC1A5 9 GO:0019692 deoxyribose phosphate metabolic process 4/566 42/18722 0.0374091043323429 0.183016848887462 TYMS/DUT/DNPH1/NUDT15 4 GO:0030890 positive regulation of B cell proliferation 4/566 42/18722 0.0374091043323429 0.183016848887462 CD74/MIF/SLC39A10/TFRC 4 GO:0045687 positive regulation of glial cell differentiation 4/566 42/18722 0.0374091043323429 0.183016848887462 IL6ST/SERPINE2/SPINT1/DAG1 4 GO:0045773 positive regulation of axon extension 4/566 42/18722 0.0374091043323429 0.183016848887462 FN1/LRP1/NRP1/MACF1 4 GO:1902100 negative regulation of metaphase/anaphase transition of cell cycle 4/566 42/18722 0.0374091043323429 0.183016848887462 MAD2L1/CCNB1/BUB3/ZWINT 4 GO:0001910 regulation of leukocyte mediated cytotoxicity 6/566 82/18722 0.0377658654308206 0.184559421402869 HLA-B/HLA-DRB1/TYROBP/HLA-A/HLA-DRA/B2M 6 GO:0048661 positive regulation of smooth muscle cell proliferation 7/566 104/18722 0.0383401672615895 0.187160553342759 CYBA/EGFR/HPGD/AIF1/GNAI3/GJA1/P2RY6 7 GO:0051204 protein insertion into mitochondrial membrane 3/566 25/18722 0.0385906179132768 0.187560514137454 TOMM22/PDCD5/TIMM9 3 GO:0060074 synapse maturation 3/566 25/18722 0.0385906179132768 0.187560514137454 PFN1/CDC20/CLSTN1 3 GO:0086064 cell communication by electrical coupling involved in cardiac conduction 3/566 25/18722 0.0385906179132768 0.187560514137454 CALM1/SRI/GJA1 3 GO:0098581 detection of external biotic stimulus 3/566 25/18722 0.0385906179132768 0.187560514137454 HLA-B/HLA-DRB1/HLA-A 3 GO:1903825 organic acid transmembrane transport 9/566 150/18722 0.0387378341911963 0.188070706454968 LRP2/SLC2A1/SLC19A1/SLC38A2/ITGB1/SLC38A10/SLC43A2/FOLR1/SLC1A5 9 GO:1901990 regulation of mitotic cell cycle phase transition 15/566 299/18722 0.0389847721506833 0.188628889558404 RPL26/ANXA1/MAD2L1/CCNB1/EGFR/CDK1/BUB3/TRIAP1/CDK2AP2/ZWINT/ANAPC11/APP/AIF1/GPNMB/CDC26 15 GO:0009311 oligosaccharide metabolic process 5/566 62/18722 0.039191761644547 0.188628889558404 B4GALT1/GAA/HEXB/MOGS/GM2A 5 GO:0032613 interleukin-10 production 5/566 62/18722 0.039191761644547 0.188628889558404 HMGB1/HLA-DRB1/TYROBP/HSPD1/CD46 5 GO:0032653 regulation of interleukin-10 production 5/566 62/18722 0.039191761644547 0.188628889558404 HMGB1/HLA-DRB1/TYROBP/HSPD1/CD46 5 GO:0032731 positive regulation of interleukin-1 beta production 5/566 62/18722 0.039191761644547 0.188628889558404 HMGB1/TYROBP/ISL1/APP/MNDA 5 GO:0045428 regulation of nitric oxide biosynthetic process 5/566 62/18722 0.039191761644547 0.188628889558404 DYNLL1/HSP90AB1/ATP2B4/AIF1/HBB 5 GO:0046824 positive regulation of nucleocytoplasmic transport 5/566 62/18722 0.039191761644547 0.188628889558404 RAN/HSP90AB1/NUTF2/CDH1/CDK1 5 GO:0060135 maternal process involved in female pregnancy 5/566 62/18722 0.039191761644547 0.188628889558404 SPP1/PRDX3/DAZAP1/GJA1/CTSB 5 GO:0046785 microtubule polymerization 6/566 83/18722 0.0397137580238688 0.190934827993805 RPS3/STMN1/MET/AKAP9/TUBGCP2/CLIP1 6 GO:2001022 positive regulation of response to DNA damage stimulus 7/566 105/18722 0.0400565793214652 0.192375287097263 RPS3/RPL26/HMGB1/EEF1E1/UBE2N/EGFR/UBE2V2 7 GO:0006261 DNA-dependent DNA replication 9/566 151/18722 0.0401417499275013 0.192487822009787 ALYREF/CCNE1/POLE3/RFC2/GMNN/STOML2/RFC3/RAD51/DBF4 9 GO:0030517 negative regulation of axon extension 4/566 43/18722 0.040296192747781 0.192487822009787 SEMA6D/SEMA3F/NRP1/SEMA6A 4 GO:0031952 regulation of protein autophosphorylation 4/566 43/18722 0.040296192747781 0.192487822009787 CALM1/ENG/GPNMB/IQGAP1 4 GO:0036230 granulocyte activation 4/566 43/18722 0.040296192747781 0.192487822009787 TYROBP/FCER1G/ANXA3/GRN 4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 4/566 43/18722 0.040296192747781 0.192487822009787 CD74/RPL26/MIF/TRIAP1 4 GO:0001952 regulation of cell-matrix adhesion 8/566 128/18722 0.0406228047068828 0.193425375994698 ACTG1/LRP1/S100A10/NRP1/DAG1/IQGAP1/MACF1/SERPINE1 8 GO:0032612 interleukin-1 production 8/566 128/18722 0.0406228047068828 0.193425375994698 HMGB1/TYROBP/ANXA1/GSTP1/SERPINB1/ISL1/APP/MNDA 8 GO:0032652 regulation of interleukin-1 production 8/566 128/18722 0.0406228047068828 0.193425375994698 HMGB1/TYROBP/ANXA1/GSTP1/SERPINB1/ISL1/APP/MNDA 8 GO:0002366 leukocyte activation involved in immune response 14/566 275/18722 0.0406732311652051 0.193434687141288 RPS6/CD74/LGALS1/HMGB1/HLA-DRB1/TYROBP/FCER1G/ANXA1/HLA-DRA/ANXA3/HSPD1/GRN/CD46/TFRC 14 GO:0002791 regulation of peptide secretion 11/566 200/18722 0.0411270370564186 0.193434687141288 CD74/DYNLL1/HLA-DRB1/LRP1/EGFR/ISL1/PHPT1/DPP4/LRP5/SRI/GJA1 11 GO:0030239 myofibril assembly 5/566 63/18722 0.0415557949145243 0.193434687141288 KRT19/ACTG1/CSRP2/KRT8/ITGB1 5 GO:1902373 negative regulation of mRNA catabolic process 5/566 63/18722 0.0415557949145243 0.193434687141288 YBX1/YBX3/HNRNPC/HNRNPD/CIRBP 5 GO:0009185 ribonucleoside diphosphate metabolic process 7/566 106/18722 0.0418223553297132 0.193434687141288 GAPDH/LDHA/TPI1/ALDOA/ENO1/PKM/APP 7 GO:0046620 regulation of organ growth 7/566 106/18722 0.0418223553297132 0.193434687141288 YBX3/CCNB1/CDK1/SLC6A4/CGA/IGF2/GJA1 7 GO:0046822 regulation of nucleocytoplasmic transport 7/566 106/18722 0.0418223553297132 0.193434687141288 RAN/HSP90AB1/NUTF2/CDH1/CDK1/PARK7/TXN 7 GO:1903707 negative regulation of hemopoiesis 7/566 106/18722 0.0418223553297132 0.193434687141288 FBN1/CD74/HMGB1/ANXA1/NME1/HSPA9/NME2 7 GO:0001731 formation of translation preinitiation complex 2/566 11/18722 0.0418847795157687 0.193434687141288 RPL13A/EIF2S2 2 GO:0003093 regulation of glomerular filtration 2/566 11/18722 0.0418847795157687 0.193434687141288 CYBA/GJA1 2 GO:0003139 secondary heart field specification 2/566 11/18722 0.0418847795157687 0.193434687141288 LRP2/ISL1 2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c 2/566 11/18722 0.0418847795157687 0.193434687141288 UQCRH/CYCS 2 GO:0009155 purine deoxyribonucleotide catabolic process 2/566 11/18722 0.0418847795157687 0.193434687141288 DNPH1/NUDT15 2 GO:0009313 oligosaccharide catabolic process 2/566 11/18722 0.0418847795157687 0.193434687141288 HEXB/GM2A 2 GO:0019372 lipoxygenase pathway 2/566 11/18722 0.0418847795157687 0.193434687141288 HPGD/GPX1 2 GO:0021561 facial nerve development 2/566 11/18722 0.0418847795157687 0.193434687141288 SEMA3F/NRP1 2 GO:0021604 cranial nerve structural organization 2/566 11/18722 0.0418847795157687 0.193434687141288 SEMA3F/NRP1 2 GO:0021610 facial nerve morphogenesis 2/566 11/18722 0.0418847795157687 0.193434687141288 SEMA3F/NRP1 2 GO:0032329 serine transport 2/566 11/18722 0.0418847795157687 0.193434687141288 SLC38A2/SLC1A5 2 GO:0033690 positive regulation of osteoblast proliferation 2/566 11/18722 0.0418847795157687 0.193434687141288 ITGAV/LRP5 2 GO:0035404 histone-serine phosphorylation 2/566 11/18722 0.0418847795157687 0.193434687141288 CCNB1/VRK1 2 GO:0043589 skin morphogenesis 2/566 11/18722 0.0418847795157687 0.193434687141288 ITGA6/ITGB4 2 GO:0045654 positive regulation of megakaryocyte differentiation 2/566 11/18722 0.0418847795157687 0.193434687141288 HMGB2/SCIN 2 GO:0045657 positive regulation of monocyte differentiation 2/566 11/18722 0.0418847795157687 0.193434687141288 CD74/HLA-DRB1 2 GO:0048680 positive regulation of axon regeneration 2/566 11/18722 0.0418847795157687 0.193434687141288 LRP1/GRN 2 GO:0055015 ventricular cardiac muscle cell development 2/566 11/18722 0.0418847795157687 0.193434687141288 CCNB1/CDK1 2 GO:0071679 commissural neuron axon guidance 2/566 11/18722 0.0418847795157687 0.193434687141288 NRP1/DAG1 2 GO:1900426 positive regulation of defense response to bacterium 2/566 11/18722 0.0418847795157687 0.193434687141288 CYBA/GRN 2 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction 2/566 11/18722 0.0418847795157687 0.193434687141288 CALM1/SRI 2 GO:0034101 erythrocyte homeostasis 8/566 129/18722 0.0422165248799053 0.194458838480527 RPS6/RPS17/HMGB2/PRDX1/SLC25A5/RPS19/B2M/HSPA9 8 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 8/566 129/18722 0.0422165248799053 0.194458838480527 RPS3/HMGB1/CYCS/HSPD1/HSPE1/PDCD5/CTSD/PDCD2 8 GO:0006027 glycosaminoglycan catabolic process 3/566 26/18722 0.0426743677438175 0.194458838480527 GNS/NAGLU/GLB1 3 GO:0006517 protein deglycosylation 3/566 26/18722 0.0426743677438175 0.194458838480527 PARK7/AMFR/EDEM3 3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane 3/566 26/18722 0.0426743677438175 0.194458838480527 SRP9/SRP19/SEC61A1 3 GO:0006706 steroid catabolic process 3/566 26/18722 0.0426743677438175 0.194458838480527 APOE/SPP1/STS 3 GO:0010875 positive regulation of cholesterol efflux 3/566 26/18722 0.0426743677438175 0.194458838480527 APOE/LRP1/ABCA1 3 GO:0016226 iron-sulfur cluster assembly 3/566 26/18722 0.0426743677438175 0.194458838480527 HSPA9/GLRX3/LYRM4 3 GO:0031163 metallo-sulfur cluster assembly 3/566 26/18722 0.0426743677438175 0.194458838480527 HSPA9/GLRX3/LYRM4 3 GO:0046697 decidualization 3/566 26/18722 0.0426743677438175 0.194458838480527 SPP1/GJA1/CTSB 3 GO:0048668 collateral sprouting 3/566 26/18722 0.0426743677438175 0.194458838480527 SPP1/LRP1/APP 3 GO:0051350 negative regulation of lyase activity 3/566 26/18722 0.0426743677438175 0.194458838480527 PHPT1/AKAP9/GNAI3 3 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity 3/566 26/18722 0.0426743677438175 0.194458838480527 CALM1/GSTO1/SRI 3 GO:0007162 negative regulation of cell adhesion 15/566 303/18722 0.0429392579341755 0.195266165804851 CD74/LGALS1/HMGB1/HLA-DRB1/ANXA1/LRP1/CDH1/SERPINE2/PLXNA1/PLXNB1/GPNMB/FBLN1/PLXNB2/SERPINE1/SEMA6A 15 GO:0015849 organic acid transport 15/566 303/18722 0.0429392579341755 0.195266165804851 LRP2/PLIN2/APOE/ANXA1/SLC2A1/SLC26A2/SLC19A1/SLC38A2/ITGB1/SLC38A10/SLC43A2/GJA1/SLC27A2/FOLR1/SLC1A5 15 GO:0005978 glycogen biosynthetic process 4/566 44/18722 0.0433064333593866 0.19593520458942 PTGES3/PPP1CA/UGP2/IGF2 4 GO:0009250 glucan biosynthetic process 4/566 44/18722 0.0433064333593866 0.19593520458942 PTGES3/PPP1CA/UGP2/IGF2 4 GO:0021762 substantia nigra development 4/566 44/18722 0.0433064333593866 0.19593520458942 DYNLL1/CALM1/YWHAQ/NDUFS3 4 GO:0045124 regulation of bone resorption 4/566 44/18722 0.0433064333593866 0.19593520458942 SPP1/EGFR/ATP6AP1/TFRC 4 GO:0050999 regulation of nitric-oxide synthase activity 4/566 44/18722 0.0433064333593866 0.19593520458942 APOE/CALM1/ATP2B4/EGFR 4 GO:0090257 regulation of muscle system process 13/566 252/18722 0.0434088370916901 0.196129828509785 CALM1/ENO1/ATP2B4/IL6ST/DAG1/AKAP9/GSTO1/DSC2/AIF1/GLRX3/SRI/ATP2B1/DSG2 13 GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 7/566 107/18722 0.0436378739386404 0.196129828509785 HLA-B/HLA-DRB1/HLA-A/HLA-DRA/B2M/HSPD1/TFRC 7 GO:0010927 cellular component assembly involved in morphogenesis 7/566 107/18722 0.0436378739386404 0.196129828509785 KRT19/ACTG1/CSRP2/KRT8/ITGB1/DAG1/ITGB4 7 GO:0036503 ERAD pathway 7/566 107/18722 0.0436378739386404 0.196129828509785 AMFR/UBXN1/HSP90B1/CANX/EDEM3/TMEM259/CALR 7 GO:0051341 regulation of oxidoreductase activity 7/566 107/18722 0.0436378739386404 0.196129828509785 APOE/CALM1/ATP2B4/CYBA/EGFR/PARK7/GNAI3 7 GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 7/566 107/18722 0.0436378739386404 0.196129828509785 MIF/HMGB1/TYROBP/CYBA/ISL1/HSPD1/APP 7 GO:0090087 regulation of peptide transport 11/566 202/18722 0.0436578302006281 0.196129828509785 CD74/DYNLL1/HLA-DRB1/LRP1/EGFR/ISL1/PHPT1/DPP4/LRP5/SRI/GJA1 11 GO:0098657 import into cell 12/566 227/18722 0.0437399599517461 0.196300707364086 LRP2/ATP2B4/SLC2A1/SLC6A4/PARK7/SLC19A1/ITGB1/SLC39A10/SLC43A2/SLC27A2/FOLR1/SLC1A5 12 GO:0006282 regulation of DNA repair 8/566 130/18722 0.0438511140864634 0.196601369499431 RPS3/HMGB1/UBE2N/EGFR/DEK/RAD51/PPP4C/UBE2V2 8 GO:0050771 negative regulation of axonogenesis 5/566 64/18722 0.0440042060230483 0.196693499211457 SPP1/SEMA6D/SEMA3F/NRP1/SEMA6A 5 GO:0055002 striated muscle cell development 5/566 64/18722 0.0440042060230483 0.196693499211457 KRT19/ACTG1/CSRP2/KRT8/ITGB1 5 GO:0080164 regulation of nitric oxide metabolic process 5/566 64/18722 0.0440042060230483 0.196693499211457 DYNLL1/HSP90AB1/ATP2B4/AIF1/HBB 5 GO:0008360 regulation of cell shape 9/566 154/18722 0.0445590814193248 0.198785024538697 FN1/ALDOA/ANXA1/PLXNA1/PLXNB1/MYL12A/DAG1/HEXB/PLXNB2 9 GO:0009896 positive regulation of catabolic process 22/566 492/18722 0.0445614228413342 0.198785024538697 LRP2/APOE/HMGB1/VDAC1/SLC25A5/LRP1/OAZ1/SUMO2/PARK7/DDA1/HNRNPD/BAG2/GABARAP/CDC20/PSMC4/BNIP3/APP/GNAI3/GJA1/UBE2V2/TMEM259/EXOSC9 22 GO:0006310 DNA recombination 15/566 305/18722 0.04501991307915 0.200629282310686 HMGB2/HMGB1/HMGB3/UBE2N/ALYREF/RPA3/HSPD1/TPRKB/RAD51/MND1/PPP4C/PSMD14/CCNB1IP1/RUVBL1/TFRC 15 GO:0140053 mitochondrial gene expression 7/566 108/18722 0.0455034871741599 0.20258152489936 MRPS15/MRPL51/MRPS35/MRPS6/MRPS7/MALSU1/MRPS28 7 GO:0009165 nucleotide biosynthetic process 13/566 254/18722 0.0457302435477866 0.203357040584322 ALDOA/ENO1/TYMS/NME1/SLC26A2/DUT/IMPDH2/RRM2/TMSB4X/UMPS/STOML2/GMPS/NME2 13 GO:0001936 regulation of endothelial cell proliferation 10/566 179/18722 0.0458147151181661 0.203357040584322 APOE/HMGB2/HMGB1/FLT1/CYBA/SPARC/NRP1/PDCD10/IGF2/GJA1 10 GO:0010950 positive regulation of endopeptidase activity 10/566 179/18722 0.0458147151181661 0.203357040584322 RPS3/HMGB1/CYCS/LGMN/HSPD1/HSPE1/PDCD5/PSMD14/CTSD/PDCD2 10 GO:2000117 negative regulation of cysteine-type endopeptidase activity 6/566 86/18722 0.0459346315971448 0.203686234930766 PRDX3/BIRC5/GPX1/PARK7/TRIAP1/PIH1D1 6 GO:0033157 regulation of intracellular protein transport 12/566 229/18722 0.0462138609975662 0.204388171535101 RAN/HSP90AB1/NUTF2/UBE2L3/CDH1/CDK1/OAZ1/PARK7/TXN/PDCD10/PDCD5/LMAN1 12 GO:0009306 protein secretion 17/566 359/18722 0.0463792708346003 0.204388171535101 APOE/DYNLL1/HLA-DRB1/ANXA1/PPIA/LRP1/EGFR/ISL1/PHPT1/PARK7/ABCA1/DPP4/LRP5/SRI/GJA1/CANX/P3H1 17 GO:0035307 positive regulation of protein dephosphorylation 4/566 45/18722 0.0464397333059432 0.204388171535101 CALM1/HSP90AB1/PPIA/SLC39A10 4 GO:0035987 endodermal cell differentiation 4/566 45/18722 0.0464397333059432 0.204388171535101 FN1/COL4A2/LAMB1/ITGAV 4 GO:0015909 long-chain fatty acid transport 5/566 65/18722 0.0465373190158498 0.204388171535101 PLIN2/APOE/ANXA1/SLC2A1/SLC27A2 5 GO:0033692 cellular polysaccharide biosynthetic process 5/566 65/18722 0.0465373190158498 0.204388171535101 PTGES3/PPP1CA/UGP2/IGF2/B3GNT3 5 GO:0070613 regulation of protein processing 5/566 65/18722 0.0465373190158498 0.204388171535101 ENO1/SERPINE2/BAG2/GLG1/SERPINE1 5 GO:0070936 protein K48-linked ubiquitination 5/566 65/18722 0.0465373190158498 0.204388171535101 PPIA/UBE2T/UBE2D2/AMFR/GABARAP 5 GO:0050727 regulation of inflammatory response 18/566 386/18722 0.0466804865211072 0.204388171535101 NEAT1/APOE/HLA-DRB1/ANXA1/IL6ST/GSTP1/EGFR/ISL1/RPS19/GPX1/PARK7/HSPD1/TMSB4X/GRN/PBK/APP/SERPINF1/SERPINE1 18 GO:0007611 learning or memory 13/566 255/18722 0.0469227729541643 0.204388171535101 APOE/VDAC1/EGFR/LGMN/SLC6A4/B2M/EIF4A3/AMFR/ITGB1/APP/SERPINF1/MME/GM2A 13 GO:0007263 nitric oxide mediated signal transduction 3/566 27/18722 0.0469652065319876 0.204388171535101 APOE/ATP2B4/EGFR 3 GO:0008053 mitochondrial fusion 3/566 27/18722 0.0469652065319876 0.204388171535101 STOML2/BNIP3/TFRC 3 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle 3/566 27/18722 0.0469652065319876 0.204388171535101 CCNB1/CDK1/APP 3 GO:0031954 positive regulation of protein autophosphorylation 3/566 27/18722 0.0469652065319876 0.204388171535101 CALM1/GPNMB/IQGAP1 3 GO:0033688 regulation of osteoblast proliferation 3/566 27/18722 0.0469652065319876 0.204388171535101 PLXNB1/ITGAV/LRP5 3 GO:0034377 plasma lipoprotein particle assembly 3/566 27/18722 0.0469652065319876 0.204388171535101 APOC1/APOE/ABCA1 3 GO:0042104 positive regulation of activated T cell proliferation 3/566 27/18722 0.0469652065319876 0.204388171535101 RPS3/HMGB1/IGF2 3 GO:1902883 negative regulation of response to oxidative stress 3/566 27/18722 0.0469652065319876 0.204388171535101 PARK7/TXN/MET 3 GO:1903205 regulation of hydrogen peroxide-induced cell death 3/566 27/18722 0.0469652065319876 0.204388171535101 PARK7/TXN/MET 3 GO:0098813 nuclear chromosome segregation 14/566 281/18722 0.0472107587413944 0.205256150309265 RAN/MAD2L1/CCNB1/NUDC/CCNE1/BUB3/CHMP5/CENPK/PTTG1/ZWINT/CDC20/ANAPC11/CCNB1IP1/CDC26 14 GO:0043409 negative regulation of MAPK cascade 10/566 180/18722 0.0472629446566257 0.205282565474437 APOE/DNAJA1/PPIA/GSTP1/PBK/DAG1/TIMP3/FBLN1/IGF1R/SEMA6A 10 GO:0035592 establishment of protein localization to extracellular region 17/566 360/18722 0.0473792269286715 0.205561542107513 APOE/DYNLL1/HLA-DRB1/ANXA1/PPIA/LRP1/EGFR/ISL1/PHPT1/PARK7/ABCA1/DPP4/LRP5/SRI/GJA1/CANX/P3H1 17 GO:0034766 negative regulation of ion transmembrane transport 7/566 109/18722 0.0474195201582245 0.205561542107513 CALM1/VDAC1/C4orf3/YWHAQ/GSTO1/SRI/SLC43A2 7 GO:0060348 bone development 11/566 205/18722 0.0476515811079167 0.206366574992651 FBN1/TYROBP/RPL13/PLXNB1/ENG/SLC38A10/LRP5/GJA1/GLG1/ATP6AP1/P3H1 11 GO:0001558 regulation of cell growth 19/566 414/18722 0.0477187500769099 0.206456632985814 FN1/NPM1/APOE/SPP1/ENO1/LRP1/CYBA/SERPINE2/EGFR/SEMA6D/SEMA3F/NRP1/CLSTN1/MACF1/DNPH1/NDUFS3/GJA1/SEMA6A/EXOSC9 19 GO:0019915 lipid storage 6/566 87/18722 0.0481352559591101 0.207031711765342 PLIN2/APOE/ITGAV/ABCA1/HEXB/GM2A 6 GO:0048041 focal adhesion assembly 6/566 87/18722 0.0481352559591101 0.207031711765342 ACTG1/LRP1/S100A10/NRP1/IQGAP1/MACF1 6 GO:0051262 protein tetramerization 6/566 87/18722 0.0481352559591101 0.207031711765342 HLA-DRB1/ALDOA/B2M/TK1/KRT10/RRM2 6 GO:0006909 phagocytosis 15/566 308/18722 0.0482730026381314 0.207031711765342 HMGB1/TYROBP/FCER1G/ANXA1/LRP1/CYBA/ANXA3/ITGAV/MET/ITGB1/ABCA1/COLEC12/AIF1/P2RY6/CALR 15 GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process 8/566 133/18722 0.0490030653030793 0.207031711765342 SUMO2/DDA1/BAG2/GABARAP/CDC20/PSMC4/UBE2V2/TMEM259 8 GO:0017038 protein import 11/566 206/18722 0.0490362807939269 0.207031711765342 RPL23/APOE/RAN/HSP90AB1/NUTF2/CDH1/CDK1/HSPD1/TOMM22/PDCD5/TXNIP 11 GO:0000491 small nucleolar ribonucleoprotein complex assembly 2/566 12/18722 0.0492755060865362 0.207031711765342 RUVBL1/PIH1D1 2 GO:0002903 negative regulation of B cell apoptotic process 2/566 12/18722 0.0492755060865362 0.207031711765342 CD74/SLC39A10 2 GO:0007320 insemination 2/566 12/18722 0.0492755060865362 0.207031711765342 SERPINE2/SLC6A4 2 GO:0009176 pyrimidine deoxyribonucleoside monophosphate metabolic process 2/566 12/18722 0.0492755060865362 0.207031711765342 TYMS/DUT 2 GO:0009265 2'-deoxyribonucleotide biosynthetic process 2/566 12/18722 0.0492755060865362 0.207031711765342 TYMS/DUT 2 GO:0033182 regulation of histone ubiquitination 2/566 12/18722 0.0492755060865362 0.207031711765342 UBE2N/PARK7 2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway 2/566 12/18722 0.0492755060865362 0.207031711765342 COL4A2/COL4A1 2 GO:0043471 regulation of cellular carbohydrate catabolic process 2/566 12/18722 0.0492755060865362 0.207031711765342 HMGB1/PPP1CA 2 GO:0046051 UTP metabolic process 2/566 12/18722 0.0492755060865362 0.207031711765342 NME1/NME2 2 GO:0046185 aldehyde catabolic process 2/566 12/18722 0.0492755060865362 0.207031711765342 PARK7/ESD 2 GO:0046385 deoxyribose phosphate biosynthetic process 2/566 12/18722 0.0492755060865362 0.207031711765342 TYMS/DUT 2 GO:0061430 bone trabecula morphogenesis 2/566 12/18722 0.0492755060865362 0.207031711765342 FBN2/PLXNB1 2 GO:0070572 positive regulation of neuron projection regeneration 2/566 12/18722 0.0492755060865362 0.207031711765342 LRP1/GRN 2 GO:0072376 protein activation cascade 2/566 12/18722 0.0492755060865362 0.207031711765342 FN1/FBLN1 2 GO:0090085 regulation of protein deubiquitination 2/566 12/18722 0.0492755060865362 0.207031711765342 PARK7/UBXN1 2 GO:0098911 regulation of ventricular cardiac muscle cell action potential 2/566 12/18722 0.0492755060865362 0.207031711765342 DSC2/DSG2 2 GO:1901298 regulation of hydrogen peroxide-mediated programmed cell death 2/566 12/18722 0.0492755060865362 0.207031711765342 PARK7/MET 2 GO:1903332 regulation of protein folding 2/566 12/18722 0.0492755060865362 0.207031711765342 GRN/PDCD5 2 GO:1905214 regulation of RNA binding 2/566 12/18722 0.0492755060865362 0.207031711765342 EIF3E/EIF4A3 2 GO:1990034 calcium ion export across plasma membrane 2/566 12/18722 0.0492755060865362 0.207031711765342 CALM1/ATP2B1 2 GO:2000105 positive regulation of DNA-dependent DNA replication 2/566 12/18722 0.0492755060865362 0.207031711765342 STOML2/DBF4 2 GO:0051017 actin filament bundle assembly 9/566 157/18722 0.0492903619383797 0.207031711765342 PFN1/ACTG1/STMN1/MARCKS/S100A10/MET/NRP1/AIF1/HSP90B1 9 GO:1902600 proton transmembrane transport 9/566 157/18722 0.0492903619383797 0.207031711765342 SLC25A5/UQCRH/COX4I1/PARK7/TMSB4X/COX7A2L/STOML2/COX5A/ATP6AP1 9 GO:2000377 regulation of reactive oxygen species metabolic process 9/566 157/18722 0.0492903619383797 0.207031711765342 TYROBP/VDAC1/CYBA/GSTP1/EGFR/PARK7/HSPD1/BNIP3/GNAI3 9 GO:0005996 monosaccharide metabolic process 13/566 257/18722 0.0493722245503109 0.207031711765342 GAPDH/HMGB1/TPI1/ALDOA/ENO1/SLC2A1/PPP1CA/B4GALT1/GSTO1/IGF2/LRP5/GAA/GLB1 13 GO:0032611 interleukin-1 beta production 7/566 110/18722 0.0493862708658566 0.207031711765342 HMGB1/TYROBP/GSTP1/SERPINB1/ISL1/APP/MNDA 7 GO:0032651 regulation of interleukin-1 beta production 7/566 110/18722 0.0493862708658566 0.207031711765342 HMGB1/TYROBP/GSTP1/SERPINB1/ISL1/APP/MNDA 7 GO:0009260 ribonucleotide biosynthetic process 10/566 182/18722 0.0502511363267509 0.210261333577721 ALDOA/ENO1/NME1/SLC26A2/IMPDH2/TMSB4X/UMPS/STOML2/GMPS/NME2 10 GO:0061138 morphogenesis of a branching epithelium 10/566 182/18722 0.0502511363267509 0.210261333577721 LAMA5/COL4A1/PPP1CA/PLXNA1/SPINT1/MET/NRP1/ENG/DAG1/LRP5 10 GO:0031110 regulation of microtubule polymerization or depolymerization 6/566 88/18722 0.0503999014431519 0.210685785187711 RPS3/STMN1/SKA2/MET/AKAP9/CLIP1 6 GO:1901987 regulation of cell cycle phase transition 18/566 390/18722 0.0506332501524739 0.211462692006392 NPM1/RPL26/ANXA1/ATP2B4/MAD2L1/CCNB1/EGFR/CDK1/BUB3/TRIAP1/CDK2AP2/ZWINT/ANAPC11/APP/AIF1/GPNMB/CDC26/DBF4 18 GO:0002705 positive regulation of leukocyte mediated immunity 8/566 134/18722 0.0508040124749907 0.211977004253663 HLA-B/HLA-DRB1/TYROBP/HLA-A/HLA-DRA/B2M/HSPD1/TFRC 8 GO:0043488 regulation of mRNA stability 9/566 158/18722 0.0509383492440473 0.212338512017321 NPM1/YBX1/VIM/YBX3/HNRNPM/HNRNPC/HNRNPD/CIRBP/EXOSC9 9 GO:0000423 mitophagy 3/566 28/18722 0.051459756305706 0.213115195416747 VDAC1/SLC25A5/VPS13C 3 GO:0031342 negative regulation of cell killing 3/566 28/18722 0.051459756305706 0.213115195416747 HLA-B/HSP90AB1/HLA-A 3 GO:0032801 receptor catabolic process 3/566 28/18722 0.051459756305706 0.213115195416747 APOE/LGMN/ZNRF3 3 GO:0045589 regulation of regulatory T cell differentiation 3/566 28/18722 0.051459756305706 0.213115195416747 HLA-DRB1/HLA-DRA/CD46 3 GO:0051503 adenine nucleotide transport 3/566 28/18722 0.051459756305706 0.213115195416747 SLC25A5/SLC19A1/GJA1 3 GO:0051894 positive regulation of focal adhesion assembly 3/566 28/18722 0.051459756305706 0.213115195416747 S100A10/NRP1/IQGAP1 3 GO:0071280 cellular response to copper ion 3/566 28/18722 0.051459756305706 0.213115195416747 AOC1/MT2A/APP 3 GO:0010517 regulation of phospholipase activity 5/566 67/18722 0.0518585309005712 0.214367854753336 FLT1/ANXA1/LRP1/EGFR/P2RY6 5 GO:1903317 regulation of protein maturation 5/566 67/18722 0.0518585309005712 0.214367854753336 ENO1/SERPINE2/BAG2/GLG1/SERPINE1 5 GO:1900407 regulation of cellular response to oxidative stress 6/566 89/18722 0.0527288129794639 0.217763149707396 PPIA/GPX1/PARK7/TXN/MET/P4HB 6 GO:0001774 microglial cell activation 4/566 47/18722 0.0530742640166452 0.218986675998243 TYROBP/GRN/APP/AIF1 4 GO:0090150 establishment of protein localization to membrane 13/566 260/18722 0.0532094870603717 0.21934132999331 CALM1/SRP9/NACA/EGFR/TOMM22/PDCD5/CLSTN1/KRT18/SRP19/MACF1/TIMM9/EMC1/SEC61A1 13 GO:0055001 muscle cell development 10/566 184/18722 0.0533629356574689 0.219614122449294 KRT19/ACTG1/CSRP2/CCNB1/ISL1/CDK1/GPX1/KRT8/ITGB1/ENG 10 GO:0032609 interferon-gamma production 7/566 112/18722 0.0534729803987049 0.219614122449294 HMGB1/HLA-DRB1/HLA-DPA1/HLA-A/HLA-DPB1/ISL1/HSPD1 7 GO:0032649 regulation of interferon-gamma production 7/566 112/18722 0.0534729803987049 0.219614122449294 HMGB1/HLA-DRB1/HLA-DPA1/HLA-A/HLA-DPB1/ISL1/HSPD1 7 GO:1901222 regulation of NIK/NF-kappaB signaling 7/566 112/18722 0.0534729803987049 0.219614122449294 RPS3/HMGB1/PRDX1/EGFR/TMSB4X/APP/CALR 7 GO:0002699 positive regulation of immune effector process 12/566 235/18722 0.0542097247919743 0.222434741727069 CD74/HLA-B/HLA-DRB1/TYROBP/HLA-A/ANXA1/HLA-DRA/RPS19/B2M/HSPD1/CD46/TFRC 12 GO:0035637 multicellular organismal signaling 9/566 160/18722 0.0543419485274153 0.222567023775578 CALM1/ATP2B4/ISL1/AKAP9/DSC2/SRI/GJA1/ATP2B1/DSG2 9 GO:0090316 positive regulation of intracellular protein transport 9/566 160/18722 0.0543419485274153 0.222567023775578 RAN/HSP90AB1/NUTF2/UBE2L3/CDH1/CDK1/OAZ1/PDCD10/PDCD5 9 GO:0046686 response to cadmium ion 5/566 68/18722 0.0546468645925126 0.223404812824487 EGFR/SPARC/CDK1/B2M/MT2A 5 GO:0051926 negative regulation of calcium ion transport 5/566 68/18722 0.0546468645925126 0.223404812824487 CALM1/VDAC1/C4orf3/GSTO1/SRI 5 GO:0001701 in utero embryonic development 17/566 367/18722 0.0548104404458002 0.223867964096057 KRT19/YBX1/BTF3/YBX3/RPL13/CCNB1/SF3B6/KRT8/SPINT1/RRM2/ITGB1/EIF2S2/CCNB2/PSMC4/IGF2/CCNB1IP1/RPL7L1 17 GO:0007369 gastrulation 10/566 185/18722 0.0549656408519954 0.224296088976245 FN1/RPS6/COL4A2/LAMB1/ITGAV/ITGB1/DAG1/ITGB4/LRP5/GJA1 10 GO:0046849 bone remodeling 6/566 90/18722 0.05512219033315 0.224728929819765 SPP1/EGFR/LRP5/GJA1/ATP6AP1/TFRC 6 GO:0002708 positive regulation of lymphocyte mediated immunity 7/566 113/18722 0.055593397729461 0.225343328197035 HLA-B/HLA-DRB1/HLA-A/HLA-DRA/B2M/HSPD1/TFRC 7 GO:0030072 peptide hormone secretion 12/566 236/18722 0.0556276989018794 0.225343328197035 DYNLL1/HLA-DRB1/ANXA1/LRP1/EGFR/ISL1/PHPT1/PARK7/DPP4/LRP5/SRI/GJA1 12 GO:0061572 actin filament bundle organization 9/566 161/18722 0.0560979444575246 0.225343328197035 PFN1/ACTG1/STMN1/MARCKS/S100A10/MET/NRP1/AIF1/HSP90B1 9 GO:0006734 NADH metabolic process 3/566 29/18722 0.0561542676966997 0.225343328197035 ENO1/MDH1/MDH2 3 GO:0009218 pyrimidine ribonucleotide metabolic process 3/566 29/18722 0.0561542676966997 0.225343328197035 NME1/UMPS/NME2 3 GO:0010955 negative regulation of protein processing 3/566 29/18722 0.0561542676966997 0.225343328197035 SERPINE2/GLG1/SERPINE1 3 GO:0015868 purine ribonucleotide transport 3/566 29/18722 0.0561542676966997 0.225343328197035 SLC25A5/SLC19A1/GJA1 3 GO:0050686 negative regulation of mRNA processing 3/566 29/18722 0.0561542676966997 0.225343328197035 NPM1/SRSF7/SRSF9 3 GO:1903318 negative regulation of protein maturation 3/566 29/18722 0.0561542676966997 0.225343328197035 SERPINE2/GLG1/SERPINE1 3 GO:0006986 response to unfolded protein 8/566 137/18722 0.0564610329466931 0.225343328197035 HSP90AB1/DNAJA1/HSPA9/HSPD1/AMFR/HSPE1/EDEM3/COPS5 8 GO:0007266 Rho protein signal transduction 8/566 137/18722 0.0564610329466931 0.225343328197035 APOE/STMN1/ADGRG1/CFL1/MET/NRP1/ITGB1/ABCA1 8 GO:0060048 cardiac muscle contraction 8/566 137/18722 0.0564610329466931 0.225343328197035 CALM1/AKAP9/GSTO1/DSC2/GAA/SRI/GJA1/DSG2 8 GO:0045839 negative regulation of mitotic nuclear division 4/566 48/18722 0.0565744510095857 0.225343328197035 MAD2L1/CCNB1/BUB3/ZWINT 4 GO:0031345 negative regulation of cell projection organization 10/566 186/18722 0.05659977270776 0.225343328197035 APOE/SPP1/LGALS1/VIM/LRP1/B2M/SEMA6D/SEMA3F/NRP1/SEMA6A 10 GO:0006163 purine nucleotide metabolic process 18/566 396/18722 0.0569977662349562 0.225343328197035 GAPDH/LDHA/RAN/TPI1/ALDOA/ENO1/PKM/NME1/SLC26A2/IMPDH2/TMSB4X/STOML2/APP/DNPH1/GMPS/GNAI3/NUDT15/NME2 18 GO:0050900 leukocyte migration 17/566 369/18722 0.0570750822141874 0.225343328197035 CD74/MIF/HMGB1/FLT1/CSF3R/FCER1G/ANXA1/PPIA/RPS19/LGMN/ITGB1/B4GALT1/APP/AIF1/DPP4/SERPINE1/CALR 17 GO:0009143 nucleoside triphosphate catabolic process 2/566 13/18722 0.0570950750687906 0.225343328197035 DUT/NUDT15 2 GO:0010635 regulation of mitochondrial fusion 2/566 13/18722 0.0570950750687906 0.225343328197035 BNIP3/TFRC 2 GO:0010745 negative regulation of macrophage derived foam cell differentiation 2/566 13/18722 0.0570950750687906 0.225343328197035 ITGAV/ABCA1 2 GO:0010958 regulation of amino acid import across plasma membrane 2/566 13/18722 0.0570950750687906 0.225343328197035 ITGB1/SLC43A2 2 GO:0031392 regulation of prostaglandin biosynthetic process 2/566 13/18722 0.0570950750687906 0.225343328197035 CD74/ANXA1 2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter 2/566 13/18722 0.0570950750687906 0.225343328197035 SUPT16H/GTF2F1 2 GO:0034112 positive regulation of homotypic cell-cell adhesion 2/566 13/18722 0.0570950750687906 0.225343328197035 LGALS1/IL6ST 2 GO:0034135 regulation of toll-like receptor 2 signaling pathway 2/566 13/18722 0.0570950750687906 0.225343328197035 HMGB1/CYBA 2 GO:0036462 TRAIL-activated apoptotic signaling pathway 2/566 13/18722 0.0570950750687906 0.225343328197035 PARK7/TIMP3 2 GO:0044794 positive regulation by host of viral process 2/566 13/18722 0.0570950750687906 0.225343328197035 APOE/CFL1 2 GO:0048711 positive regulation of astrocyte differentiation 2/566 13/18722 0.0570950750687906 0.225343328197035 IL6ST/SERPINE2 2 GO:0051481 negative regulation of cytosolic calcium ion concentration 2/566 13/18722 0.0570950750687906 0.225343328197035 LRP1/ATP2B1 2 GO:0070254 mucus secretion 2/566 13/18722 0.0570950750687906 0.225343328197035 CYBA/EGFR 2 GO:0098814 spontaneous synaptic transmission 2/566 13/18722 0.0570950750687906 0.225343328197035 ITGB1/APP 2 GO:0110096 cellular response to aldehyde 2/566 13/18722 0.0570950750687906 0.225343328197035 PARK7/ESD 2 GO:1900121 negative regulation of receptor binding 2/566 13/18722 0.0570950750687906 0.225343328197035 PTPRF/B2M 2 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding 2/566 13/18722 0.0570950750687906 0.225343328197035 TMSB4X/ZNF593 2 GO:1903789 regulation of amino acid transmembrane transport 2/566 13/18722 0.0570950750687906 0.225343328197035 ITGB1/SLC43A2 2 GO:1905907 negative regulation of amyloid fibril formation 2/566 13/18722 0.0570950750687906 0.225343328197035 APOE/PFDN4 2 GO:2001198 regulation of dendritic cell differentiation 2/566 13/18722 0.0570950750687906 0.225343328197035 HLA-B/HMGB1 2 GO:0043588 skin development 13/566 263/18722 0.0572455953309165 0.225737281145474 LAMA5/ANXA1/STMN1/EGFR/PTGES3/LGR5/ITGA6/KRT10/MET/ITGB4/NME2/ASAH1/TXNIP 13 GO:0045665 negative regulation of neuron differentiation 5/566 69/18722 0.0575203718339253 0.22625507317995 ISL1/SLC6A4/B2M/APP/CALR 5 GO:1901224 positive regulation of NIK/NF-kappaB signaling 5/566 69/18722 0.0575203718339253 0.22625507317995 RPS3/HMGB1/EGFR/APP/CALR 5 GO:0051492 regulation of stress fiber assembly 6/566 91/18722 0.0575801882104409 0.22625507317995 PFN1/ACTG1/STMN1/S100A10/MET/NRP1 6 GO:0060191 regulation of lipase activity 6/566 91/18722 0.0575801882104409 0.22625507317995 APOC1/FLT1/ANXA1/LRP1/EGFR/P2RY6 6 GO:0043523 regulation of neuron apoptotic process 11/566 212/18722 0.0579177332956305 0.227380730716179 APOE/HSP90AB1/TYROBP/LRP1/ISL1/LGMN/PARK7/HSPD1/NRP1/GRN/UBE2V2 11 GO:0009409 response to cold 4/566 49/18722 0.0601956219390713 0.235907490204882 HSPD1/CIRBP/ATP2B1/ADRB1 4 GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation 4/566 49/18722 0.0601956219390713 0.235907490204882 HPGD/GNAI3/GJA1/P2RY6 4 GO:0000132 establishment of mitotic spindle orientation 3/566 30/18722 0.061044656957173 0.237363208872362 MAD2L1/ITGB1/GJA1 3 GO:0009264 deoxyribonucleotide catabolic process 3/566 30/18722 0.061044656957173 0.237363208872362 DUT/DNPH1/NUDT15 3 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 3/566 30/18722 0.061044656957173 0.237363208872362 CALM1/GSTO1/SRI 3 GO:0015865 purine nucleotide transport 3/566 30/18722 0.061044656957173 0.237363208872362 SLC25A5/SLC19A1/GJA1 3 GO:0019674 NAD metabolic process 3/566 30/18722 0.061044656957173 0.237363208872362 LDHA/ENO1/MDH1 3 GO:0045940 positive regulation of steroid metabolic process 3/566 30/18722 0.061044656957173 0.237363208872362 APOC1/APOE/CGA 3 GO:0140058 neuron projection arborization 3/566 30/18722 0.061044656957173 0.237363208872362 LRP2/NRP1/MACF1 3 GO:2000648 positive regulation of stem cell proliferation 3/566 30/18722 0.061044656957173 0.237363208872362 CCNE1/GJA1/PDCD2 3 GO:0000082 G1/S transition of mitotic cell cycle 11/566 214/18722 0.0611002330116187 0.237363208872362 RPS6/RPL26/ANXA1/EGFR/CCNE1/TRIAP1/CDK2AP2/ITGB1/AIF1/GPNMB/DBF4 11 GO:0044242 cellular lipid catabolic process 11/566 214/18722 0.0611002330116187 0.237363208872362 APOC1/LRP1/ETFB/ACAT2/ECHS1/HEXB/ECH1/SLC27A2/ASAH1/HEXA/GM2A 11 GO:0033559 unsaturated fatty acid metabolic process 7/566 116/18722 0.0622650678440614 0.241677490882094 CD74/MIF/ANXA1/GSTP1/PTGES3/HPGD/GPX1 7 GO:0015748 organophosphate ester transport 8/566 140/18722 0.0625032964561043 0.242390832598063 APOC1/APOE/SLC25A5/ATP10D/TRIAP1/SLC19A1/ABCA1/GJA1 8 GO:0097306 cellular response to alcohol 6/566 93/18722 0.0626904401303206 0.242693773443641 CDH1/RAD51/DAG1/ABCA1/ATP2B1/P2RY6 6 GO:1901019 regulation of calcium ion transmembrane transporter activity 6/566 93/18722 0.0626904401303206 0.242693773443641 CALM1/C4orf3/AHNAK/GSTO1/SRI/P2RY6 6 GO:0046390 ribose phosphate biosynthetic process 10/566 190/18722 0.0634535334773752 0.244427100824834 ALDOA/ENO1/NME1/SLC26A2/IMPDH2/TMSB4X/UMPS/STOML2/GMPS/NME2 10 GO:0032635 interleukin-6 production 9/566 165/18722 0.0634871149043879 0.244427100824834 CD74/HLA-B/HMGB1/TYROBP/CYBA/ISL1/HSPD1/APP/AIF1 9 GO:0032675 regulation of interleukin-6 production 9/566 165/18722 0.0634871149043879 0.244427100824834 CD74/HLA-B/HMGB1/TYROBP/CYBA/ISL1/HSPD1/APP/AIF1 9 GO:0050796 regulation of insulin secretion 9/566 165/18722 0.0634871149043879 0.244427100824834 DYNLL1/HLA-DRB1/LRP1/ISL1/PHPT1/DPP4/LRP5/SRI/GJA1 9 GO:0032722 positive regulation of chemokine production 5/566 71/18722 0.0635224967777029 0.244427100824834 CD74/HMGB1/LRP1/APP/AIF1 5 GO:0033555 multicellular organismal response to stress 5/566 71/18722 0.0635224967777029 0.244427100824834 APOE/VDAC1/DPP4/GJA1/ADRB1 5 GO:0061515 myeloid cell development 5/566 71/18722 0.0635224967777029 0.244427100824834 RPS6/FBN1/TYROBP/APP/ATP6AP1 5 GO:0030490 maturation of SSU-rRNA 4/566 50/18722 0.0639368622657133 0.244664471798375 RPS8/RPS16/LSM6/RPS19 4 GO:1903747 regulation of establishment of protein localization to mitochondrion 4/566 50/18722 0.0639368622657133 0.244664471798375 DNAJA1/UBE2L3/PDCD5/LMAN1 4 GO:2000677 regulation of transcription regulatory region DNA binding 4/566 50/18722 0.0639368622657133 0.244664471798375 PARK7/TMSB4X/ZNF593/SRI 4 GO:0009612 response to mechanical stimulus 11/566 216/18722 0.0643954974333732 0.244664471798375 CYBA/SERPINE2/CCNB1/EGFR/SLC2A1/SLC38A2/ENG/DAG1/BNIP3/GJA1/TXNIP 11 GO:0001894 tissue homeostasis 13/566 268/18722 0.0644229040616787 0.244664471798375 LYZ/SPP1/ACTG1/PRDX1/LAMC1/EGFR/SLC2A1/B2M/ITGB1/FH/GJA1/ATP6AP1/TFRC 13 GO:0051225 spindle assembly 7/566 117/18722 0.0645928701689588 0.244664471798375 RPS3/HAUS1/CHMP5/CCNB2/CDC20/HAUS8/TUBGCP2 7 GO:0016241 regulation of macroautophagy 8/566 141/18722 0.0646037039993525 0.244664471798375 GAPDH/VDAC1/QSOX1/SLC25A5/BNIP3/VPS13C/GNAI3/SMG1 8 GO:0072503 cellular divalent inorganic cation homeostasis 21/566 486/18722 0.0651559479807884 0.244664471798375 TPT1/APOE/HMGB1/CALM1/ATP2B4/LRP1/CYBA/MT2A/ITGAV/STOML2/GSTO1/BNIP3/APP/HSP90B1/HEXB/SRI/SLC39A10/GJA1/ATP2B1/P2RY6/CALR 21 GO:0046879 hormone secretion 14/566 295/18722 0.0652348414018986 0.244664471798375 SPP1/DYNLL1/HLA-DRB1/ANXA1/LRP1/EGFR/ISL1/PHPT1/PARK7/CGA/DPP4/LRP5/SRI/GJA1 14 GO:0000054 ribosomal subunit export from nucleus 2/566 14/18722 0.0653109026980024 0.244664471798375 NPM1/RAN 2 GO:0006241 CTP biosynthetic process 2/566 14/18722 0.0653109026980024 0.244664471798375 NME1/NME2 2 GO:0006521 regulation of cellular amino acid metabolic process 2/566 14/18722 0.0653109026980024 0.244664471798375 ATP2B4/PARK7 2 GO:0006596 polyamine biosynthetic process 2/566 14/18722 0.0653109026980024 0.244664471798375 OAZ1/SMS 2 GO:0010872 regulation of cholesterol esterification 2/566 14/18722 0.0653109026980024 0.244664471798375 APOC1/APOE 2 GO:0018158 protein oxidation 2/566 14/18722 0.0653109026980024 0.244664471798375 PRDX3/GPX1 2 GO:0033750 ribosome localization 2/566 14/18722 0.0653109026980024 0.244664471798375 NPM1/RAN 2 GO:0035641 locomotory exploration behavior 2/566 14/18722 0.0653109026980024 0.244664471798375 APOE/DPP4 2 GO:0042921 glucocorticoid receptor signaling pathway 2/566 14/18722 0.0653109026980024 0.244664471798375 PTGES3/CALR 2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 2/566 14/18722 0.0653109026980024 0.244664471798375 RPL26/EEF1E1 2 GO:0043558 regulation of translational initiation in response to stress 2/566 14/18722 0.0653109026980024 0.244664471798375 NPM1/PPP1CA 2 GO:0051764 actin crosslink formation 2/566 14/18722 0.0653109026980024 0.244664471798375 MARCKS/AIF1 2 GO:0060576 intestinal epithelial cell development 2/566 14/18722 0.0653109026980024 0.244664471798375 IL6ST/TYMS 2 GO:0070141 response to UV-A 2/566 14/18722 0.0653109026980024 0.244664471798375 EGFR/MME 2 GO:0071285 cellular response to lithium ion 2/566 14/18722 0.0653109026980024 0.244664471798375 CDH1/CALR 2 GO:0090128 regulation of synapse maturation 2/566 14/18722 0.0653109026980024 0.244664471798375 CDC20/CLSTN1 2 GO:1900037 regulation of cellular response to hypoxia 2/566 14/18722 0.0653109026980024 0.244664471798375 ENO1/CHCHD2 2 GO:1905049 negative regulation of metallopeptidase activity 2/566 14/18722 0.0653109026980024 0.244664471798375 LRP1/TIMP3 2 GO:2001140 positive regulation of phospholipid transport 2/566 14/18722 0.0653109026980024 0.244664471798375 APOE/TRIAP1 2 GO:2001171 positive regulation of ATP biosynthetic process 2/566 14/18722 0.0653109026980024 0.244664471798375 ENO1/TMSB4X 2 GO:0002690 positive regulation of leukocyte chemotaxis 6/566 94/18722 0.0653427800917043 0.244664471798375 CD74/HMGB1/LGMN/AIF1/SERPINE1/CALR 6 GO:0032091 negative regulation of protein binding 6/566 94/18722 0.0653427800917043 0.244664471798375 PTPRF/PPP1CA/B2M/PARK7/BAG2/GTF2F1 6 GO:0051702 biological process involved in interaction with symbiont 6/566 94/18722 0.0653427800917043 0.244664471798375 FN1/GAPDH/APOE/GPX1/CFL1/HSPD1 6 GO:0061013 regulation of mRNA catabolic process 9/566 166/18722 0.0654264042847937 0.244771724265464 NPM1/YBX1/VIM/YBX3/HNRNPM/HNRNPC/HNRNPD/CIRBP/EXOSC9 9 GO:0006613 cotranslational protein targeting to membrane 3/566 31/18722 0.0661265407407122 0.245739031200042 SRP9/SRP19/SEC61A1 3 GO:0007190 activation of adenylate cyclase activity 3/566 31/18722 0.0661265407407122 0.245739031200042 CALM1/LGR5/ADRB1 3 GO:0032148 activation of protein kinase B activity 3/566 31/18722 0.0661265407407122 0.245739031200042 PPIA/PARK7/TXN 3 GO:0045066 regulatory T cell differentiation 3/566 31/18722 0.0661265407407122 0.245739031200042 HLA-DRB1/HLA-DRA/CD46 3 GO:0046386 deoxyribose phosphate catabolic process 3/566 31/18722 0.0661265407407122 0.245739031200042 DUT/DNPH1/NUDT15 3 GO:0065005 protein-lipid complex assembly 3/566 31/18722 0.0661265407407122 0.245739031200042 APOC1/APOE/ABCA1 3 GO:0071480 cellular response to gamma radiation 3/566 31/18722 0.0661265407407122 0.245739031200042 RPL26/CYBA/RAD51 3 GO:1901797 negative regulation of signal transduction by p53 class mediator 3/566 31/18722 0.0661265407407122 0.245739031200042 CD74/MIF/TRIAP1 3 GO:0000271 polysaccharide biosynthetic process 5/566 72/18722 0.0666507160044442 0.247163851044991 PTGES3/PPP1CA/UGP2/IGF2/B3GNT3 5 GO:0032729 positive regulation of interferon-gamma production 5/566 72/18722 0.0666507160044442 0.247163851044991 HLA-DPA1/HLA-A/HLA-DPB1/ISL1/HSPD1 5 GO:0050890 cognition 14/566 296/18722 0.0666765015959197 0.247163851044991 APOE/VDAC1/HLA-DRA/EGFR/LGMN/SLC6A4/B2M/EIF4A3/AMFR/ITGB1/APP/SERPINF1/MME/GM2A 14 GO:0071346 cellular response to interferon-gamma 7/566 118/18722 0.0669727786641304 0.24805558287247 GAPDH/RPL13A/VIM/ACTG1/HSP90AB1/HLA-DPA1/AIF1 7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone 4/566 51/18722 0.0677971116729203 0.249448546419703 PARK7/NDUFB3/NDUFA10/NDUFS3 4 GO:0006636 unsaturated fatty acid biosynthetic process 4/566 51/18722 0.0677971116729203 0.249448546419703 CD74/MIF/ANXA1/PTGES3 4 GO:0032873 negative regulation of stress-activated MAPK cascade 4/566 51/18722 0.0677971116729203 0.249448546419703 DNAJA1/PPIA/GSTP1/PBK 4 GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation 4/566 51/18722 0.0677971116729203 0.249448546419703 HMGB1/HLA-DRB1/ANXA1/HLA-DRA 4 GO:0046850 regulation of bone remodeling 4/566 51/18722 0.0677971116729203 0.249448546419703 SPP1/EGFR/ATP6AP1/TFRC 4 GO:0051293 establishment of spindle localization 4/566 51/18722 0.0677971116729203 0.249448546419703 MAD2L1/CFL1/ITGB1/GJA1 4 GO:0051339 regulation of lyase activity 4/566 51/18722 0.0677971116729203 0.249448546419703 PHPT1/PARK7/AKAP9/GNAI3 4 GO:0070303 negative regulation of stress-activated protein kinase signaling cascade 4/566 51/18722 0.0677971116729203 0.249448546419703 DNAJA1/PPIA/GSTP1/PBK 4 GO:0006898 receptor-mediated endocytosis 12/566 244/18722 0.0678724652439678 0.249519583209038 LRP2/APOC1/APOE/FCER1G/LRP1/B2M/ITGAV/ITGB1/CANX/FOLR1/SERPINE1/TFRC 12 GO:0006942 regulation of striated muscle contraction 6/566 95/18722 0.0680599130362475 0.249796152380358 CALM1/AKAP9/GSTO1/DSC2/SRI/DSG2 6 GO:0050764 regulation of phagocytosis 6/566 95/18722 0.0680599130362475 0.249796152380358 HMGB1/FCER1G/LRP1/CYBA/ITGAV/CALR 6 GO:0001935 endothelial cell proliferation 10/566 193/18722 0.0689304936360433 0.252382484264911 APOE/HMGB2/HMGB1/FLT1/CYBA/SPARC/NRP1/PDCD10/IGF2/GJA1 10 GO:0034763 negative regulation of transmembrane transport 8/566 143/18722 0.0689346587749623 0.252382484264911 CALM1/VDAC1/C4orf3/YWHAQ/OAZ1/GSTO1/SRI/SLC43A2 8 GO:0038061 NIK/NF-kappaB signaling 8/566 143/18722 0.0689346587749623 0.252382484264911 RPS3/HMGB1/PRDX1/EGFR/TMSB4X/PPP4C/APP/CALR 8 GO:0030900 forebrain development 17/566 379/18722 0.0693720393589565 0.253312133928636 LRP2/TYROBP/ATP2B4/LRP1/CDH1/NME1/ISL1/SLC2A1/B2M/ADGRG1/ARPC5/LAMB1/ANXA3/SLC38A2/NRP1/BNIP3/APP 17 GO:0031398 positive regulation of protein ubiquitination 7/566 119/18722 0.0694048415451226 0.253312133928636 NPM1/RPS2/UBE2L3/UBE2N/UBE2S/GABARAP/CDC20 7 GO:0002706 regulation of lymphocyte mediated immunity 9/566 168/18722 0.0694161732688535 0.253312133928636 HLA-B/HMGB1/HLA-DRB1/HLA-A/HLA-DRA/B2M/HSPD1/CD46/TFRC 9 GO:0002833 positive regulation of response to biotic stimulus 9/566 168/18722 0.0694161732688535 0.253312133928636 HMGB2/HMGB1/HLA-DRB1/TYROBP/CYBA/RPS19/HSPD1/GRN/MNDA 9 GO:0032732 positive regulation of interleukin-1 production 5/566 73/18722 0.0698633147638368 0.254110684091994 HMGB1/TYROBP/ISL1/APP/MNDA 5 GO:0035924 cellular response to vascular endothelial growth factor stimulus 5/566 73/18722 0.0698633147638368 0.254110684091994 FLT1/ANXA1/ATP2B4/NRP1/SEMA6A 5 GO:0045739 positive regulation of DNA repair 5/566 73/18722 0.0698633147638368 0.254110684091994 RPS3/HMGB1/UBE2N/EGFR/UBE2V2 5 GO:0086003 cardiac muscle cell contraction 5/566 73/18722 0.0698633147638368 0.254110684091994 AKAP9/DSC2/SRI/GJA1/DSG2 5 GO:0010769 regulation of cell morphogenesis involved in differentiation 6/566 96/18722 0.0708417720380314 0.256604588927242 S100A10/ARPC2/NRP1/FBLN1/P4HB/CALR 6 GO:0030510 regulation of BMP signaling pathway 6/566 96/18722 0.0708417720380314 0.256604588927242 FBN1/LRP2/CRIM1/FSTL1/ENG/HTRA1 6 GO:1901655 cellular response to ketone 6/566 96/18722 0.0708417720380314 0.256604588927242 SPP1/EGFR/PARK7/SERPINF1/ATP2B1/P2RY6 6 GO:0006026 aminoglycan catabolic process 3/566 32/18722 0.0713952687585632 0.256604588927242 GNS/NAGLU/GLB1 3 GO:0010644 cell communication by electrical coupling 3/566 32/18722 0.0713952687585632 0.256604588927242 CALM1/SRI/GJA1 3 GO:0033687 osteoblast proliferation 3/566 32/18722 0.0713952687585632 0.256604588927242 PLXNB1/ITGAV/LRP5 3 GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation 3/566 32/18722 0.0713952687585632 0.256604588927242 HLA-DRB1/ANXA1/HLA-DRA 3 GO:0051497 negative regulation of stress fiber assembly 3/566 32/18722 0.0713952687585632 0.256604588927242 PFN1/STMN1/MET 3 GO:0060914 heart formation 3/566 32/18722 0.0713952687585632 0.256604588927242 LRP2/ISL1/FOLR1 3 GO:0097345 mitochondrial outer membrane permeabilization 3/566 32/18722 0.0713952687585632 0.256604588927242 VDAC2/SLC25A5/BNIP3 3 GO:0009152 purine ribonucleotide biosynthetic process 9/566 169/18722 0.0714668260556027 0.256604588927242 ALDOA/ENO1/NME1/SLC26A2/IMPDH2/TMSB4X/STOML2/GMPS/NME2 9 GO:0021543 pallium development 9/566 169/18722 0.0714668260556027 0.256604588927242 ATP2B4/LRP1/NME1/SLC2A1/ADGRG1/LAMB1/ANXA3/SLC38A2/BNIP3 9 GO:0021545 cranial nerve development 4/566 52/18722 0.0717751704296717 0.256604588927242 RPL24/ISL1/SEMA3F/NRP1 4 GO:0030514 negative regulation of BMP signaling pathway 4/566 52/18722 0.0717751704296717 0.256604588927242 FBN1/LRP2/CRIM1/HTRA1 4 GO:0045010 actin nucleation 4/566 52/18722 0.0717751704296717 0.256604588927242 ARPC2/ARPC5/ARPC1A/SCIN 4 GO:2000378 negative regulation of reactive oxygen species metabolic process 4/566 52/18722 0.0717751704296717 0.256604588927242 VDAC1/PARK7/HSPD1/BNIP3 4 GO:0002761 regulation of myeloid leukocyte differentiation 7/566 120/18722 0.0718890792536332 0.256604588927242 FBN1/CD74/HLA-DRB1/TYROBP/NME1/NME2/ATP6AP1 7 GO:0032411 positive regulation of transporter activity 7/566 120/18722 0.0718890792536332 0.256604588927242 CALM1/PARK7/TMSB4X/AKAP9/GSTO1/GLRX/P2RY6 7 GO:0002437 inflammatory response to antigenic stimulus 5/566 74/18722 0.0731599071943065 0.256604588927242 HMGB2/HMGB1/HLA-DRB1/GPX1/PARK7 5 GO:0003151 outflow tract morphogenesis 5/566 74/18722 0.0731599071943065 0.256604588927242 LRP2/ISL1/NRP1/ENG/FOLR1 5 GO:0006635 fatty acid beta-oxidation 5/566 74/18722 0.0731599071943065 0.256604588927242 ETFB/ACAT2/ECHS1/ECH1/SLC27A2 5 GO:0010822 positive regulation of mitochondrion organization 5/566 74/18722 0.0731599071943065 0.256604588927242 VDAC1/SLC25A5/PARK7/PDCD5/BNIP3 5 GO:0000722 telomere maintenance via recombination 2/566 15/18722 0.0738919773146282 0.256604588927242 TPRKB/RAD51 2 GO:0002679 respiratory burst involved in defense response 2/566 15/18722 0.0738919773146282 0.256604588927242 RPS19/GRN 2 GO:0002836 positive regulation of response to tumor cell 2/566 15/18722 0.0738919773146282 0.256604588927242 HLA-DRB1/HSPD1 2 GO:0002839 positive regulation of immune response to tumor cell 2/566 15/18722 0.0738919773146282 0.256604588927242 HLA-DRB1/HSPD1 2 GO:0006089 lactate metabolic process 2/566 15/18722 0.0738919773146282 0.256604588927242 LDHA/PARK7 2 GO:0006271 DNA strand elongation involved in DNA replication 2/566 15/18722 0.0738919773146282 0.256604588927242 POLE3/RFC3 2 GO:0006878 cellular copper ion homeostasis 2/566 15/18722 0.0738919773146282 0.256604588927242 MT2A/APP 2 GO:0009209 pyrimidine ribonucleoside triphosphate biosynthetic process 2/566 15/18722 0.0738919773146282 0.256604588927242 NME1/NME2 2 GO:0010273 detoxification of copper ion 2/566 15/18722 0.0738919773146282 0.256604588927242 PARK7/MT2A 2 GO:0015671 oxygen transport 2/566 15/18722 0.0738919773146282 0.256604588927242 HBA2/HBB 2 GO:0019511 peptidyl-proline hydroxylation 2/566 15/18722 0.0738919773146282 0.256604588927242 P3H1/P4HB 2 GO:0031958 corticosteroid receptor signaling pathway 2/566 15/18722 0.0738919773146282 0.256604588927242 PTGES3/CALR 2 GO:0032933 SREBP signaling pathway 2/566 15/18722 0.0738919773146282 0.256604588927242 AMFR/EIF2A 2 GO:0034380 high-density lipoprotein particle assembly 2/566 15/18722 0.0738919773146282 0.256604588927242 APOE/ABCA1 2 GO:0042159 lipoprotein catabolic process 2/566 15/18722 0.0738919773146282 0.256604588927242 APOE/CTSD 2 GO:0042994 cytoplasmic sequestering of transcription factor 2/566 15/18722 0.0738919773146282 0.256604588927242 TMSB4X/SRI 2 GO:0043508 negative regulation of JUN kinase activity 2/566 15/18722 0.0738919773146282 0.256604588927242 DNAJA1/GSTP1 2 GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator 2/566 15/18722 0.0738919773146282 0.256604588927242 CD74/MIF 2 GO:0045475 locomotor rhythm 2/566 15/18722 0.0738919773146282 0.256604588927242 NAGLU/ZFHX3 2 GO:0051290 protein heterotetramerization 2/566 15/18722 0.0738919773146282 0.256604588927242 KRT10/RRM2 2 GO:0055012 ventricular cardiac muscle cell differentiation 2/566 15/18722 0.0738919773146282 0.256604588927242 CCNB1/CDK1 2 GO:0070207 protein homotrimerization 2/566 15/18722 0.0738919773146282 0.256604588927242 MIF/SLC1A5 2 GO:0070831 basement membrane assembly 2/566 15/18722 0.0738919773146282 0.256604588927242 LAMB1/DAG1 2 GO:0071428 rRNA-containing ribonucleoprotein complex export from nucleus 2/566 15/18722 0.0738919773146282 0.256604588927242 NPM1/RAN 2 GO:0071474 cellular hyperosmotic response 2/566 15/18722 0.0738919773146282 0.256604588927242 YBX3/SLC2A1 2 GO:0086069 bundle of His cell to Purkinje myocyte communication 2/566 15/18722 0.0738919773146282 0.256604588927242 DSC2/DSG2 2 GO:0099170 postsynaptic modulation of chemical synaptic transmission 2/566 15/18722 0.0738919773146282 0.256604588927242 CDH1/EIF4A3 2 GO:1901836 regulation of transcription of nucleolar large rRNA by RNA polymerase I 2/566 15/18722 0.0738919773146282 0.256604588927242 NCL/PIH1D1 2 GO:1901841 regulation of high voltage-gated calcium channel activity 2/566 15/18722 0.0738919773146282 0.256604588927242 CALM1/SRI 2 GO:1903727 positive regulation of phospholipid metabolic process 2/566 15/18722 0.0738919773146282 0.256604588927242 STOML2/RAB38 2 GO:1904380 endoplasmic reticulum mannose trimming 2/566 15/18722 0.0738919773146282 0.256604588927242 AMFR/EDEM3 2 GO:1904424 regulation of GTP binding 2/566 15/18722 0.0738919773146282 0.256604588927242 STMN1/MET 2 GO:1905146 lysosomal protein catabolic process 2/566 15/18722 0.0738919773146282 0.256604588927242 LRP2/LRP1 2 GO:1990169 stress response to copper ion 2/566 15/18722 0.0738919773146282 0.256604588927242 PARK7/MT2A 2 GO:2001138 regulation of phospholipid transport 2/566 15/18722 0.0738919773146282 0.256604588927242 APOE/TRIAP1 2 GO:2001279 regulation of unsaturated fatty acid biosynthetic process 2/566 15/18722 0.0738919773146282 0.256604588927242 CD74/ANXA1 2 GO:0001704 formation of primary germ layer 7/566 121/18722 0.0744254845623238 0.25825585134175 FN1/COL4A2/LAMB1/ITGAV/ITGB1/ITGB4/GJA1 7 GO:0001763 morphogenesis of a branching structure 10/566 196/18722 0.0746989860294505 0.258600222241923 LAMA5/COL4A1/PPP1CA/PLXNA1/SPINT1/MET/NRP1/ENG/DAG1/LRP5 10 GO:0031032 actomyosin structure organization 10/566 196/18722 0.0746989860294505 0.258600222241923 KRT19/PFN1/ACTG1/CSRP2/STMN1/S100A10/KRT8/MET/NRP1/ITGB1 10 GO:0090276 regulation of peptide hormone secretion 10/566 196/18722 0.0746989860294505 0.258600222241923 DYNLL1/HLA-DRB1/LRP1/EGFR/ISL1/PHPT1/DPP4/LRP5/SRI/GJA1 10 GO:0008347 glial cell migration 4/566 53/18722 0.0758697057797336 0.261838705528197 LRP1/ADGRG1/LAMB1/HEXB 4 GO:0032784 regulation of DNA-templated transcription, elongation 4/566 53/18722 0.0758697057797336 0.261838705528197 HMGN1/ALYREF/SUPT16H/GTF2F1 4 GO:0050819 negative regulation of coagulation 4/566 53/18722 0.0758697057797336 0.261838705528197 APOE/SERPINE2/ANXA5/SERPINE1 4 GO:2000772 regulation of cellular senescence 4/566 53/18722 0.0758697057797336 0.261838705528197 YBX1/EEF1E1/B2M/RSL1D1 4 GO:0046883 regulation of hormone secretion 12/566 249/18722 0.0763541266875941 0.262561925607489 SPP1/DYNLL1/HLA-DRB1/ANXA1/LRP1/EGFR/ISL1/PHPT1/DPP4/LRP5/SRI/GJA1 12 GO:0032642 regulation of chemokine production 6/566 98/18722 0.0765991849468386 0.262561925607489 CD74/HMGB1/LRP1/GSTP1/APP/AIF1 6 GO:1902882 regulation of response to oxidative stress 6/566 98/18722 0.0765991849468386 0.262561925607489 PPIA/GPX1/PARK7/TXN/MET/P4HB 6 GO:1904062 regulation of cation transmembrane transport 16/566 357/18722 0.0768075132558103 0.262561925607489 CALM1/VDAC1/ATP2B4/C4orf3/CYBA/PARK7/AHNAK/TMSB4X/ITGB1/AKAP9/GSTO1/APP/GLRX/SRI/SLC43A2/P2RY6 16 GO:0002274 myeloid leukocyte activation 11/566 223/18722 0.0768285210539053 0.262561925607489 CD74/MIF/HMGB1/TYROBP/FCER1G/ANXA3/HSPD1/ITGB8/GRN/APP/AIF1 11 GO:0009156 ribonucleoside monophosphate biosynthetic process 3/566 33/18722 0.0768459544174658 0.262561925607489 IMPDH2/UMPS/GMPS 3 GO:0034110 regulation of homotypic cell-cell adhesion 3/566 33/18722 0.0768459544174658 0.262561925607489 LGALS1/IL6ST/SERPINE2 3 GO:0048048 embryonic eye morphogenesis 3/566 33/18722 0.0768459544174658 0.262561925607489 FBN2/FBN1/EFEMP1 3 GO:0048333 mesodermal cell differentiation 3/566 33/18722 0.0768459544174658 0.262561925607489 ITGB1/ITGB4/GJA1 3 GO:0060260 regulation of transcription initiation from RNA polymerase II promoter 3/566 33/18722 0.0768459544174658 0.262561925607489 HMGB1/SUB1/MED4 3 GO:0061842 microtubule organizing center localization 3/566 33/18722 0.0768459544174658 0.262561925607489 MAD2L1/ARPC5/AKAP9 3 GO:0150117 positive regulation of cell-substrate junction organization 3/566 33/18722 0.0768459544174658 0.262561925607489 S100A10/NRP1/IQGAP1 3 GO:1903715 regulation of aerobic respiration 3/566 33/18722 0.0768459544174658 0.262561925607489 PARK7/COX7A2L/BNIP3 3 GO:0031109 microtubule polymerization or depolymerization 7/566 122/18722 0.0770140227073546 0.262732895856814 RPS3/STMN1/SKA2/MET/AKAP9/TUBGCP2/CLIP1 7 GO:0051208 sequestering of calcium ion 7/566 122/18722 0.0770140227073546 0.262732895856814 CALM1/CYBA/GSTO1/HSP90B1/SRI/P2RY6/CALR 7 GO:0009259 ribonucleotide metabolic process 17/566 385/18722 0.0775486631526558 0.264151988030316 GAPDH/LDHA/RAN/TPI1/ALDOA/ENO1/PKM/NME1/SLC26A2/IMPDH2/TMSB4X/UMPS/STOML2/APP/GMPS/GNAI3/NME2 17 GO:0042326 negative regulation of phosphorylation 17/566 385/18722 0.0775486631526558 0.264151988030316 NPM1/APOE/DYNLL1/CALM1/DNAJA1/PPIA/LRP1/GSTP1/PKIB/CCNB1/PRDX3/PARK7/ENG/PBK/PLPP3/LRP5/FBLN1 17 GO:0001889 liver development 8/566 147/18722 0.0781188866722069 0.265890889498979 RPS16/ANXA1/TYMS/EGFR/RPL19/HNRNPD/MET/KRT18 8 GO:0071214 cellular response to abiotic stimulus 15/566 331/18722 0.0787733719584213 0.26770919996862 NPM1/RPL26/YBX3/CYBA/EGFR/SLC2A1/TRIAP1/SLC38A2/RAD51/ENG/PBK/DAG1/BNIP3/GJA1/MME 15 GO:0104004 cellular response to environmental stimulus 15/566 331/18722 0.0787733719584213 0.26770919996862 NPM1/RPL26/YBX3/CYBA/EGFR/SLC2A1/TRIAP1/SLC38A2/RAD51/ENG/PBK/DAG1/BNIP3/GJA1/MME 15 GO:0043434 response to peptide hormone 18/566 414/18722 0.0793746152104231 0.268863392242247 FBN1/ANXA1/PKM/CYBA/GSTP1/SLC2A1/CACYBP/SPARC/DAG1/CCNA2/IGF2/LRP5/IQGAP1/VPS13C/GJA1/NME2/ATP2B1/IGF1R 18 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage 6/566 99/18722 0.0795743909538048 0.268863392242247 TPT1/RPS3/CD74/RPL26/MIF/TRIAP1 6 GO:0032602 chemokine production 6/566 99/18722 0.0795743909538048 0.268863392242247 CD74/HMGB1/LRP1/GSTP1/APP/AIF1 6 GO:0060291 long-term synaptic potentiation 6/566 99/18722 0.0795743909538048 0.268863392242247 APOE/TYROBP/SERPINE2/LGMN/APP/MME 6 GO:0006690 icosanoid metabolic process 7/566 123/18722 0.0796546315478667 0.268863392242247 CD74/MIF/ANXA1/GSTP1/PTGES3/HPGD/GPX1 7 GO:0050852 T cell receptor signaling pathway 7/566 123/18722 0.0796546315478667 0.268863392242247 RPS3/HLA-DRB1/HLA-A/HLA-DPB1/UBE2N/PHPT1/STOML2 7 GO:0001937 negative regulation of endothelial cell proliferation 5/566 76/18722 0.0800031728280091 0.268863392242247 APOE/FLT1/SPARC/PDCD10/GJA1 5 GO:0006809 nitric oxide biosynthetic process 5/566 76/18722 0.0800031728280091 0.268863392242247 DYNLL1/HSP90AB1/ATP2B4/AIF1/HBB 5 GO:0045685 regulation of glial cell differentiation 5/566 76/18722 0.0800031728280091 0.268863392242247 IL6ST/SERPINE2/CDK1/SPINT1/DAG1 5 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator 5/566 76/18722 0.0800031728280091 0.268863392242247 CD74/RPL26/MIF/RPL11/TRIAP1 5 GO:0086001 cardiac muscle cell action potential 5/566 76/18722 0.0800031728280091 0.268863392242247 CALM1/AKAP9/DSC2/GJA1/DSG2 5 GO:0140115 export across plasma membrane 5/566 76/18722 0.0800031728280091 0.268863392242247 CALM1/ABCA1/SLC40A1/GJA1/ATP2B1 5 GO:0001706 endoderm formation 4/566 54/18722 0.0800792583363027 0.268863392242247 FN1/COL4A2/LAMB1/ITGAV 4 GO:0006968 cellular defense response 4/566 54/18722 0.0800792583363027 0.268863392242247 TYROBP/ITGB1/LGALS3BP/MNDA 4 GO:0010524 positive regulation of calcium ion transport into cytosol 4/566 54/18722 0.0800792583363027 0.268863392242247 CALM1/GSTO1/SRI/P2RY6 4 GO:0070839 metal ion export 4/566 54/18722 0.0800792583363027 0.268863392242247 CALM1/ATP2B4/SLC40A1/ATP2B1 4 GO:0022898 regulation of transmembrane transporter activity 13/566 278/18722 0.080508610533559 0.26929492513338 CALM1/C4orf3/PARK7/AHNAK/TMSB4X/ITGB1/AKAP9/GSTO1/APP/GLRX/SRI/GJA1/P2RY6 13 GO:0070507 regulation of microtubule cytoskeleton organization 8/566 148/18722 0.0805239060478827 0.26929492513338 RPS3/STMN1/SKA2/CHMP5/CDK2AP2/MET/AKAP9/CLIP1 8 GO:1903900 regulation of viral life cycle 8/566 148/18722 0.0805239060478827 0.26929492513338 CD74/LGALS1/HLA-DRB1/PPIA/BANF1/IFITM2/PPIH/P4HB 8 GO:0072521 purine-containing compound metabolic process 18/566 416/18722 0.0821752631137186 0.26929492513338 GAPDH/LDHA/RAN/TPI1/ALDOA/ENO1/PKM/NME1/SLC26A2/IMPDH2/TMSB4X/STOML2/APP/DNPH1/GMPS/GNAI3/NUDT15/NME2 18 GO:1902105 regulation of leukocyte differentiation 13/566 279/18722 0.0822461869608786 0.26929492513338 FBN1/CD74/HLA-B/HMGB1/HLA-DRB1/TYROBP/ANXA1/HLA-DRA/NME1/CD46/NME2/ATP6AP1/CLPTM1 13 GO:0009914 hormone transport 14/566 306/18722 0.082262079866017 0.26929492513338 SPP1/DYNLL1/HLA-DRB1/ANXA1/LRP1/EGFR/ISL1/PHPT1/PARK7/CGA/DPP4/LRP5/SRI/GJA1 14 GO:0009112 nucleobase metabolic process 3/566 34/18722 0.0824735035404758 0.26929492513338 TYMS/UMPS/GMPS 3 GO:0009303 rRNA transcription 3/566 34/18722 0.0824735035404758 0.26929492513338 NCL/NIFK/PIH1D1 3 GO:0010922 positive regulation of phosphatase activity 3/566 34/18722 0.0824735035404758 0.26929492513338 CALM1/HSP90AB1/SLC39A10 3 GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 3/566 34/18722 0.0824735035404758 0.26929492513338 CALM1/GSTO1/SRI 3 GO:0019320 hexose catabolic process 3/566 34/18722 0.0824735035404758 0.26929492513338 ENO1/LRP5/GLB1 3 GO:0032743 positive regulation of interleukin-2 production 3/566 34/18722 0.0824735035404758 0.26929492513338 RPS3/ANXA1/STOML2 3 GO:0032770 positive regulation of monooxygenase activity 3/566 34/18722 0.0824735035404758 0.26929492513338 APOE/CALM1/PARK7 3 GO:0034724 DNA replication-independent nucleosome organization 3/566 34/18722 0.0824735035404758 0.26929492513338 ITGB3BP/HAT1/SUPT16H 3 GO:0098751 bone cell development 3/566 34/18722 0.0824735035404758 0.26929492513338 FBN1/TYROBP/ATP6AP1 3 GO:0051495 positive regulation of cytoskeleton organization 11/566 226/18722 0.0825897393142816 0.26929492513338 RPS3/PFN1/S100A10/ARPC2/ARPC5/MET/NRP1/ARPC1A/AKAP9/SCIN/CLIP1 11 GO:0006626 protein targeting to mitochondrion 6/566 100/18722 0.082613628332589 0.26929492513338 UBE2L3/HSPD1/TOMM22/PDCD5/LMAN1/TIMM9 6 GO:0110020 regulation of actomyosin structure organization 6/566 100/18722 0.082613628332589 0.26929492513338 PFN1/ACTG1/STMN1/S100A10/MET/NRP1 6 GO:0001977 renal system process involved in regulation of blood volume 2/566 16/18722 0.0828087943637909 0.26929492513338 CYBA/GJA1 2 GO:0006206 pyrimidine nucleobase metabolic process 2/566 16/18722 0.0828087943637909 0.26929492513338 TYMS/UMPS 2 GO:0006266 DNA ligation 2/566 16/18722 0.0828087943637909 0.26929492513338 HMGB1/RAD51 2 GO:0009415 response to water 2/566 16/18722 0.0828087943637909 0.26929492513338 ATP2B4/KRT8 2 GO:0021783 preganglionic parasympathetic fiber development 2/566 16/18722 0.0828087943637909 0.26929492513338 SEMA3F/NRP1 2 GO:0032274 gonadotropin secretion 2/566 16/18722 0.0828087943637909 0.26929492513338 CGA/GJA1 2 GO:0034375 high-density lipoprotein particle remodeling 2/566 16/18722 0.0828087943637909 0.26929492513338 APOC1/APOE 2 GO:0035970 peptidyl-threonine dephosphorylation 2/566 16/18722 0.0828087943637909 0.26929492513338 PPP1CA/PPM1G 2 GO:0045838 positive regulation of membrane potential 2/566 16/18722 0.0828087943637909 0.26929492513338 STOML2/GLRX 2 GO:0046036 CTP metabolic process 2/566 16/18722 0.0828087943637909 0.26929492513338 NME1/NME2 2 GO:0046037 GMP metabolic process 2/566 16/18722 0.0828087943637909 0.26929492513338 IMPDH2/GMPS 2 GO:0051014 actin filament severing 2/566 16/18722 0.0828087943637909 0.26929492513338 CFL1/SCIN 2 GO:0051238 sequestering of metal ion 2/566 16/18722 0.0828087943637909 0.26929492513338 FTL/SRI 2 GO:0061548 ganglion development 2/566 16/18722 0.0828087943637909 0.26929492513338 SEMA3F/NRP1 2 GO:0070365 hepatocyte differentiation 2/566 16/18722 0.0828087943637909 0.26929492513338 ANXA1/KRT18 2 GO:0071501 cellular response to sterol depletion 2/566 16/18722 0.0828087943637909 0.26929492513338 AMFR/EIF2A 2 GO:0071732 cellular response to nitric oxide 2/566 16/18722 0.0828087943637909 0.26929492513338 HNRNPD/CCNA2 2 GO:0090231 regulation of spindle checkpoint 2/566 16/18722 0.0828087943637909 0.26929492513338 MAD2L1/CCNB1 2 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint 2/566 16/18722 0.0828087943637909 0.26929492513338 MAD2L1/CCNB1 2 GO:0097284 hepatocyte apoptotic process 2/566 16/18722 0.0828087943637909 0.26929492513338 KRT8/KRT18 2 GO:1901163 regulation of trophoblast cell migration 2/566 16/18722 0.0828087943637909 0.26929492513338 GJA1/CALR 2 GO:1902570 protein localization to nucleolus 2/566 16/18722 0.0828087943637909 0.26929492513338 NPM1/RAN 2 GO:1903504 regulation of mitotic spindle checkpoint 2/566 16/18722 0.0828087943637909 0.26929492513338 MAD2L1/CCNB1 2 GO:2000765 regulation of cytoplasmic translation 2/566 16/18722 0.0828087943637909 0.26929492513338 YBX3/PKM 2 GO:2001267 regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 2/566 16/18722 0.0828087943637909 0.26929492513338 PARK7/PIH1D1 2 GO:0045834 positive regulation of lipid metabolic process 8/566 149/18722 0.0829724850127142 0.269433627481111 CD74/APOC1/APOE/FLT1/ANXA1/CGA/STOML2/RAB38 8 GO:0051592 response to calcium ion 8/566 149/18722 0.0829724850127142 0.269433627481111 CALM1/EGFR/CACYBP/SPARC/LGMN/HNRNPD/IQGAP1/TXNIP 8 GO:0002200 somatic diversification of immune receptors 5/566 77/18722 0.0835487228282635 0.270909624203517 HMGB2/HMGB1/HSPD1/CTNNBL1/TFRC 5 GO:0007492 endoderm development 5/566 77/18722 0.0835487228282635 0.270909624203517 FN1/COL4A2/LAMC1/LAMB1/ITGAV 5 GO:0001666 response to hypoxia 14/566 307/18722 0.083938793289412 0.271976352055649 MALAT1/LDHA/ENO1/CYBA/CCNB1/SLC2A1/SLC6A4/HSPD1/CHCHD2/CCNA2/BNIP3/DPP4/HSP90B1/P4HB 14 GO:0003229 ventricular cardiac muscle tissue development 4/566 55/18722 0.0844022484628681 0.272882215073848 LRP2/ISL1/ENG/DSG2 4 GO:0006414 translational elongation 4/566 55/18722 0.0844022484628681 0.272882215073848 EEF1B2/EEF1A1/SRP9/EIF4A3 4 GO:0098900 regulation of action potential 4/566 55/18722 0.0844022484628681 0.272882215073848 CALM1/AKAP9/DSC2/DSG2 4 GO:0061008 hepaticobiliary system development 8/566 150/18722 0.0854645780167433 0.276116328977171 RPS16/ANXA1/TYMS/EGFR/RPL19/HNRNPD/MET/KRT18 8 GO:0043534 blood vessel endothelial cell migration 9/566 176/18722 0.0868670020459816 0.280240502252688 APOE/HMGB1/ANXA1/ATP2B4/GPX1/TMSB4X/NRP1/ITGB1/PDCD10 9 GO:0050728 negative regulation of inflammatory response 9/566 176/18722 0.0868670020459816 0.280240502252688 APOE/HLA-DRB1/GSTP1/ISL1/RPS19/GPX1/GRN/PBK/SERPINF1 9 GO:0016051 carbohydrate biosynthetic process 10/566 202/18722 0.087116957204527 0.280843369641241 TPI1/PTGES3/PPP1CA/UGP2/B4GALT1/IMPA2/IGF2/NANS/B3GNT3/P2RY6 10 GO:0006874 cellular calcium ion homeostasis 19/566 448/18722 0.0878468237734515 0.282446339981823 TPT1/APOE/HMGB1/CALM1/ATP2B4/LRP1/CYBA/ITGAV/STOML2/GSTO1/BNIP3/APP/HSP90B1/HEXB/SRI/GJA1/ATP2B1/P2RY6/CALR 19 GO:0048592 eye morphogenesis 8/566 151/18722 0.0880001208469108 0.282446339981823 FBN2/FBN1/HMGN1/TENM3/EFEMP1/TUG1/LRP5/NAGLU 8 GO:0048754 branching morphogenesis of an epithelial tube 8/566 151/18722 0.0880001208469108 0.282446339981823 LAMA5/COL4A1/PPP1CA/MET/NRP1/ENG/DAG1/LRP5 8 GO:0001569 branching involved in blood vessel morphogenesis 3/566 35/18722 0.0882726412676519 0.282446339981823 COL4A1/NRP1/ENG 3 GO:0006298 mismatch repair 3/566 35/18722 0.0882726412676519 0.282446339981823 HMGB1/RPA3/RNASEH2A 3 GO:0018149 peptide cross-linking 3/566 35/18722 0.0882726412676519 0.282446339981823 FN1/ANXA1/KRT10 3 GO:0032232 negative regulation of actin filament bundle assembly 3/566 35/18722 0.0882726412676519 0.282446339981823 PFN1/STMN1/MET 3 GO:0040001 establishment of mitotic spindle localization 3/566 35/18722 0.0882726412676519 0.282446339981823 MAD2L1/ITGB1/GJA1 3 GO:0098810 neurotransmitter reuptake 3/566 35/18722 0.0882726412676519 0.282446339981823 SLC6A4/PARK7/ITGB1 3 GO:1903514 release of sequestered calcium ion into cytosol by endoplasmic reticulum 3/566 35/18722 0.0882726412676519 0.282446339981823 CALM1/GSTO1/SRI 3 GO:0010332 response to gamma radiation 4/566 56/18722 0.0888369826227808 0.282446339981823 RPL26/CYBA/GPX1/RAD51 4 GO:0046456 icosanoid biosynthetic process 4/566 56/18722 0.0888369826227808 0.282446339981823 CD74/MIF/ANXA1/PTGES3 4 GO:0046622 positive regulation of organ growth 4/566 56/18722 0.0888369826227808 0.282446339981823 YBX3/CCNB1/CDK1/IGF2 4 GO:0051653 spindle localization 4/566 56/18722 0.0888369826227808 0.282446339981823 MAD2L1/CFL1/ITGB1/GJA1 4 GO:0051784 negative regulation of nuclear division 4/566 56/18722 0.0888369826227808 0.282446339981823 MAD2L1/CCNB1/BUB3/ZWINT 4 GO:0070534 protein K63-linked ubiquitination 4/566 56/18722 0.0888369826227808 0.282446339981823 UBE2N/UBE2T/UBE2S/UBE2V2 4 GO:0006672 ceramide metabolic process 6/566 102/18722 0.0888830463419889 0.282446339981823 ITGB8/PLPP3/HEXB/ASAH1/HEXA/GM2A 6 GO:0032677 regulation of interleukin-8 production 6/566 102/18722 0.0888830463419889 0.282446339981823 CD74/HMGB1/ANXA1/PARK7/TMSB4X/SERPINE1 6 GO:1902106 negative regulation of leukocyte differentiation 6/566 102/18722 0.0888830463419889 0.282446339981823 FBN1/CD74/HMGB1/ANXA1/NME1/NME2 6 GO:1904063 negative regulation of cation transmembrane transport 6/566 102/18722 0.0888830463419889 0.282446339981823 CALM1/VDAC1/C4orf3/GSTO1/SRI/SLC43A2 6 GO:0051047 positive regulation of secretion 14/566 310/18722 0.0890989942893421 0.282930615246898 SPP1/DYNLL1/HLA-DRB1/PPIA/LRP1/CYBA/EGFR/ISL1/PHPT1/SLC6A4/SRI/SCIN/GJA1/ATP6AP1 14 GO:0098739 import across plasma membrane 9/566 177/18722 0.0892165411790224 0.283101953905209 LRP2/ATP2B4/SLC2A1/SLC19A1/ITGB1/SLC39A10/SLC43A2/FOLR1/SLC1A5 9 GO:0071559 response to transforming growth factor beta 12/566 256/18722 0.0893187650583739 0.283224460142365 FBN2/FBN1/COL4A2/HSP90AB1/HPGD/ITGB8/ENG/PDCD5/GLG1/FOLR1/ZFHX3/HTRA1 12 GO:0044262 cellular carbohydrate metabolic process 13/566 283/18722 0.0894333090375289 0.283385830487601 HMGB1/TPI1/IL6ST/PTGES3/PPP1CA/UGP2/B4GALT1/IMPA2/IGF2/GAA/GLB1/B3GNT3/P2RY6 13 GO:0000245 spliceosomal complex assembly 5/566 79/18722 0.0908843493962499 0.28597285839565 SNRPD1/SNRPE/SRSF9/SNRPD2/SNRPG 5 GO:0001895 retina homeostasis 5/566 79/18722 0.0908843493962499 0.28597285839565 LYZ/ACTG1/PRDX1/SLC2A1/B2M 5 GO:0010770 positive regulation of cell morphogenesis involved in differentiation 5/566 79/18722 0.0908843493962499 0.28597285839565 S100A10/ARPC2/NRP1/P4HB/CALR 5 GO:0051279 regulation of release of sequestered calcium ion into cytosol 5/566 79/18722 0.0908843493962499 0.28597285839565 CALM1/CYBA/GSTO1/SRI/P2RY6 5 GO:1901888 regulation of cell junction assembly 10/566 204/18722 0.091517999749264 0.28597285839565 ACTG1/LRP1/S100A10/NRP1/CLSTN1/APP/IQGAP1/MACF1/GJA1/UBE2V2 10 GO:0001780 neutrophil homeostasis 2/566 17/18722 0.0920332938772967 0.28597285839565 HMGB1/ANXA1 2 GO:0009151 purine deoxyribonucleotide metabolic process 2/566 17/18722 0.0920332938772967 0.28597285839565 DNPH1/NUDT15 2 GO:0010224 response to UV-B 2/566 17/18722 0.0920332938772967 0.28597285839565 HMGN1/MME 2 GO:0010715 regulation of extracellular matrix disassembly 2/566 17/18722 0.0920332938772967 0.28597285839565 LRP1/DPP4 2 GO:0015867 ATP transport 2/566 17/18722 0.0920332938772967 0.28597285839565 SLC25A5/GJA1 2 GO:0021924 cell proliferation in external granule layer 2/566 17/18722 0.0920332938772967 0.28597285839565 SLC6A4/PSMG1 2 GO:0021930 cerebellar granule cell precursor proliferation 2/566 17/18722 0.0920332938772967 0.28597285839565 SLC6A4/PSMG1 2 GO:0033151 V(D)J recombination 2/566 17/18722 0.0920332938772967 0.28597285839565 HMGB2/HMGB1 2 GO:0035729 cellular response to hepatocyte growth factor stimulus 2/566 17/18722 0.0920332938772967 0.28597285839565 LGMN/NRP1 2 GO:0038065 collagen-activated signaling pathway 2/566 17/18722 0.0920332938772967 0.28597285839565 COL4A2/COL4A1 2 GO:0043968 histone H2A acetylation 2/566 17/18722 0.0920332938772967 0.28597285839565 MORF4L2/RUVBL1 2 GO:0044539 long-chain fatty acid import into cell 2/566 17/18722 0.0920332938772967 0.28597285839565 SLC2A1/SLC27A2 2 GO:0048532 anatomical structure arrangement 2/566 17/18722 0.0920332938772967 0.28597285839565 SEMA3F/NRP1 2 GO:0060033 anatomical structure regression 2/566 17/18722 0.0920332938772967 0.28597285839565 FLT1/LRP5 2 GO:0060263 regulation of respiratory burst 2/566 17/18722 0.0920332938772967 0.28597285839565 RPS19/GRN 2 GO:0060977 coronary vasculature morphogenesis 2/566 17/18722 0.0920332938772967 0.28597285839565 LRP2/NRP1 2 GO:0070875 positive regulation of glycogen metabolic process 2/566 17/18722 0.0920332938772967 0.28597285839565 HMGB1/IGF2 2 GO:0090399 replicative senescence 2/566 17/18722 0.0920332938772967 0.28597285839565 MME/SERPINE1 2 GO:0140354 lipid import into cell 2/566 17/18722 0.0920332938772967 0.28597285839565 SLC2A1/SLC27A2 2 GO:1902358 sulfate transmembrane transport 2/566 17/18722 0.0920332938772967 0.28597285839565 SLC26A2/SLC13A4 2 GO:1903358 regulation of Golgi organization 2/566 17/18722 0.0920332938772967 0.28597285839565 PDCD10/AKAP9 2 GO:1904355 positive regulation of telomere capping 2/566 17/18722 0.0920332938772967 0.28597285839565 PKIB/HNRNPD 2 GO:0014013 regulation of gliogenesis 6/566 103/18722 0.0921125514239357 0.28597285839565 LRP2/IL6ST/SERPINE2/EGFR/SPINT1/DAG1 6 GO:0032637 interleukin-8 production 6/566 103/18722 0.0921125514239357 0.28597285839565 CD74/HMGB1/ANXA1/PARK7/TMSB4X/SERPINE1 6 GO:0031348 negative regulation of defense response 12/566 258/18722 0.0932580570940124 0.289327435667277 APOE/HLA-B/HLA-DRB1/HLA-A/GSTP1/ISL1/RPS19/GPX1/GRN/PBK/SERPINF1/HTRA1 12 GO:0006754 ATP biosynthetic process 4/566 57/18722 0.0933816596816037 0.289509156617339 ALDOA/ENO1/TMSB4X/STOML2 4 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 7/566 128/18722 0.0936346703547888 0.290091546568907 FBN2/FBN1/HSP90AB1/ENG/GLG1/FOLR1/HTRA1 7 GO:0009150 purine ribonucleotide metabolic process 16/566 368/18722 0.0939874452849527 0.290701682795756 GAPDH/LDHA/RAN/TPI1/ALDOA/ENO1/PKM/NME1/SLC26A2/IMPDH2/TMSB4X/STOML2/APP/GMPS/GNAI3/NME2 16 GO:0006941 striated muscle contraction 9/566 179/18722 0.0940274984784115 0.290701682795756 CALM1/ALDOA/AKAP9/GSTO1/DSC2/GAA/SRI/GJA1/DSG2 9 GO:1901991 negative regulation of mitotic cell cycle phase transition 9/566 179/18722 0.0940274984784115 0.290701682795756 RPL26/MAD2L1/CCNB1/CDK1/BUB3/TRIAP1/CDK2AP2/ZWINT/GPNMB 9 GO:0019693 ribose phosphate metabolic process 17/566 396/18722 0.0941367786420363 0.29083757010017 GAPDH/LDHA/RAN/TPI1/ALDOA/ENO1/PKM/NME1/SLC26A2/IMPDH2/TMSB4X/UMPS/STOML2/APP/GMPS/GNAI3/NME2 17 GO:0070873 regulation of glycogen metabolic process 3/566 36/18722 0.0942379372291237 0.290948194552052 HMGB1/PPP1CA/IGF2 3 GO:0045927 positive regulation of growth 12/566 259/18722 0.0952669436897104 0.293921298202766 FN1/YBX3/LRP1/CYBA/CCNB1/EGFR/CDK1/NRP1/IGF2/MACF1/DNPH1/EXOSC9 12 GO:0048863 stem cell differentiation 10/566 206/18722 0.096049767786001 0.296131278520275 FN1/LAMA5/ISL1/SEMA6D/SEMA3F/HSPA9/NRP1/KRT18/FOLR1/SEMA6A 10 GO:0006605 protein targeting 14/566 314/18722 0.0962835720309504 0.296646686977018 UBE2L3/RPL11/SRP9/YWHAQ/NACA/HSPD1/TOMM22/GABARAP/PDCD5/LMAN1/SRP19/TIMM9/VPS13C/SEC61A1 14 GO:0048660 regulation of smooth muscle cell proliferation 9/566 180/18722 0.0964887907848214 0.296958520971609 APOE/CYBA/GSTP1/EGFR/HPGD/AIF1/GNAI3/GJA1/P2RY6 9 GO:0007093 mitotic cell cycle checkpoint signaling 7/566 129/18722 0.0965848918164624 0.296958520971609 RPL26/MAD2L1/CCNB1/CDK1/BUB3/TRIAP1/ZWINT 7 GO:0007127 meiosis I 7/566 129/18722 0.0965848918164624 0.296958520971609 CCNE1/PTTG1/CKS2/RAD51/MND1/CCNB2/CCNB1IP1 7 GO:0001933 negative regulation of protein phosphorylation 15/566 342/18722 0.0970120244940489 0.298065930329541 NPM1/APOE/CALM1/DNAJA1/PPIA/LRP1/GSTP1/PKIB/CCNB1/PARK7/ENG/PBK/PLPP3/LRP5/FBLN1 15 GO:0051091 positive regulation of DNA-binding transcription factor activity 12/566 260/18722 0.0973019819137108 0.298750636882649 NPM1/RPS3/PPIA/UBE2N/PRDX3/PARK7/ANXA3/APP/PLPP3/LRP5/COPS5/TFRC 12 GO:0001954 positive regulation of cell-matrix adhesion 4/566 58/18722 0.0980343771478105 0.299347768904014 S100A10/NRP1/DAG1/IQGAP1 4 GO:0002763 positive regulation of myeloid leukocyte differentiation 4/566 58/18722 0.0980343771478105 0.299347768904014 CD74/HLA-DRB1/TYROBP/ATP6AP1 4 GO:0006826 iron ion transport 4/566 58/18722 0.0980343771478105 0.299347768904014 FTL/B2M/SLC40A1/TFRC 4 GO:0018208 peptidyl-proline modification 4/566 58/18722 0.0980343771478105 0.299347768904014 PPIA/PPIH/P3H1/P4HB 4 GO:0032481 positive regulation of type I interferon production 4/566 58/18722 0.0980343771478105 0.299347768904014 GAPDH/HMGB2/HMGB1/HSPD1 4 GO:0035904 aorta development 4/566 58/18722 0.0980343771478105 0.299347768904014 LRP2/LRP1/ADAMTS6/ENG 4 GO:0043666 regulation of phosphoprotein phosphatase activity 4/566 58/18722 0.0980343771478105 0.299347768904014 CALM1/HSP90AB1/HSP90B1/SLC39A10 4 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway 4/566 58/18722 0.0980343771478105 0.299347768904014 RPS3/RPL26/RPL11/PARK7 4 GO:0018105 peptidyl-serine phosphorylation 14/566 315/18722 0.0981341413362914 0.299447016606696 MIF/HSP90AB1/ATP2B4/CCNB1/EGFR/CDK1/PARK7/TXN/PDCD10/AKAP9/VRK1/APP/SMG1/TFRC 14 GO:0016064 immunoglobulin mediated immune response 10/566 207/18722 0.0983645780430587 0.299944590032669 CD74/HLA-DRB1/FCER1G/HLA-DPA1/HLA-DRA/HLA-DPB1/B2M/HSPD1/CD46/TFRC 10 GO:0046209 nitric oxide metabolic process 5/566 81/18722 0.0985408595821658 0.299969426492147 DYNLL1/HSP90AB1/ATP2B4/AIF1/HBB 5 GO:2001021 negative regulation of response to DNA damage stimulus 5/566 81/18722 0.0985408595821658 0.299969426492147 TPT1/RPS3/CD74/MIF/TRIAP1 5 GO:0006665 sphingolipid metabolic process 8/566 155/18722 0.0985748587057527 0.299969426492147 PSAP/ITGB8/PLPP3/HEXB/ASAH1/GLB1/HEXA/GM2A 8 GO:0032231 regulation of actin filament bundle assembly 6/566 105/18722 0.0987591720813806 0.300325023296658 PFN1/ACTG1/STMN1/S100A10/MET/NRP1 6 GO:0032640 tumor necrosis factor production 9/566 181/18722 0.0989871858751444 0.300365939633239 MIF/HMGB1/TYROBP/CYBA/GSTP1/ISL1/HSPD1/APP/GPNMB 9 GO:0032680 regulation of tumor necrosis factor production 9/566 181/18722 0.0989871858751444 0.300365939633239 MIF/HMGB1/TYROBP/CYBA/GSTP1/ISL1/HSPD1/APP/GPNMB 9 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3/566 37/18722 0.100363829078875 0.300365939633239 RPS8/RPS16/RPS19 3 GO:0003161 cardiac conduction system development 3/566 37/18722 0.100363829078875 0.300365939633239 ISL1/GJA1/DSG2 3 GO:0006862 nucleotide transport 3/566 37/18722 0.100363829078875 0.300365939633239 SLC25A5/SLC19A1/GJA1 3 GO:0033260 nuclear DNA replication 3/566 37/18722 0.100363829078875 0.300365939633239 GMNN/RAD51/DBF4 3 GO:0042401 cellular biogenic amine biosynthetic process 3/566 37/18722 0.100363829078875 0.300365939633239 OAZ1/SMS/PARK7 3 GO:0043403 skeletal muscle tissue regeneration 3/566 37/18722 0.100363829078875 0.300365939633239 ANXA1/GPX1/DAG1 3 GO:0043687 post-translational protein modification 3/566 37/18722 0.100363829078875 0.300365939633239 UCHL3/P3H1/COPS5 3 GO:0045730 respiratory burst 3/566 37/18722 0.100363829078875 0.300365939633239 CYBA/RPS19/GRN 3 GO:0051294 establishment of spindle orientation 3/566 37/18722 0.100363829078875 0.300365939633239 MAD2L1/ITGB1/GJA1 3 GO:0002573 myeloid leukocyte differentiation 10/566 208/18722 0.100711934192494 0.300365939633239 FBN1/CD74/HLA-DRB1/TYROBP/NME1/ITGB8/APP/NME2/ATP6AP1/TFRC 10 GO:0035051 cardiocyte differentiation 8/566 156/18722 0.101326041744879 0.300365939633239 CCNB1/EGFR/ISL1/CACYBP/CDK1/ITGB1/FOLR1/CALR 8 GO:0002643 regulation of tolerance induction 2/566 18/18722 0.101538800347714 0.300365939633239 HLA-B/HMGB1 2 GO:0003128 heart field specification 2/566 18/18722 0.101538800347714 0.300365939633239 LRP2/ISL1 2 GO:0006991 response to sterol depletion 2/566 18/18722 0.101538800347714 0.300365939633239 AMFR/EIF2A 2 GO:0008272 sulfate transport 2/566 18/18722 0.101538800347714 0.300365939633239 SLC26A2/SLC13A4 2 GO:0009208 pyrimidine ribonucleoside triphosphate metabolic process 2/566 18/18722 0.101538800347714 0.300365939633239 NME1/NME2 2 GO:0021534 cell proliferation in hindbrain 2/566 18/18722 0.101538800347714 0.300365939633239 SLC6A4/PSMG1 2 GO:0030889 negative regulation of B cell proliferation 2/566 18/18722 0.101538800347714 0.300365939633239 TYROBP/MNDA 2 GO:0034134 toll-like receptor 2 signaling pathway 2/566 18/18722 0.101538800347714 0.300365939633239 HMGB1/CYBA 2 GO:0034433 steroid esterification 2/566 18/18722 0.101538800347714 0.300365939633239 APOC1/APOE 2 GO:0034434 sterol esterification 2/566 18/18722 0.101538800347714 0.300365939633239 APOC1/APOE 2 GO:0034435 cholesterol esterification 2/566 18/18722 0.101538800347714 0.300365939633239 APOC1/APOE 2 GO:0036507 protein demannosylation 2/566 18/18722 0.101538800347714 0.300365939633239 AMFR/EDEM3 2 GO:0036508 protein alpha-1,2-demannosylation 2/566 18/18722 0.101538800347714 0.300365939633239 AMFR/EDEM3 2 GO:0042790 nucleolar large rRNA transcription by RNA polymerase I 2/566 18/18722 0.101538800347714 0.300365939633239 NCL/PIH1D1 2 GO:0045116 protein neddylation 2/566 18/18722 0.101538800347714 0.300365939633239 RPL5/RPL11 2 GO:0045953 negative regulation of natural killer cell mediated cytotoxicity 2/566 18/18722 0.101538800347714 0.300365939633239 HLA-B/HLA-A 2 GO:0046112 nucleobase biosynthetic process 2/566 18/18722 0.101538800347714 0.300365939633239 UMPS/GMPS 2 GO:0048486 parasympathetic nervous system development 2/566 18/18722 0.101538800347714 0.300365939633239 SEMA3F/NRP1 2 GO:0055070 copper ion homeostasis 2/566 18/18722 0.101538800347714 0.300365939633239 MT2A/APP 2 GO:0060192 negative regulation of lipase activity 2/566 18/18722 0.101538800347714 0.300365939633239 APOC1/ANXA1 2 GO:0060973 cell migration involved in heart development 2/566 18/18722 0.101538800347714 0.300365939633239 ENG/FOLR1 2 GO:0061484 hematopoietic stem cell homeostasis 2/566 18/18722 0.101538800347714 0.300365939633239 FSTL1/ADGRG1 2 GO:0061687 detoxification of inorganic compound 2/566 18/18722 0.101538800347714 0.300365939633239 PARK7/MT2A 2 GO:1900424 regulation of defense response to bacterium 2/566 18/18722 0.101538800347714 0.300365939633239 CYBA/GRN 2 GO:1902074 response to salt 2/566 18/18722 0.101538800347714 0.300365939633239 HNRNPA1/HNRNPD 2 GO:1902170 cellular response to reactive nitrogen species 2/566 18/18722 0.101538800347714 0.300365939633239 HNRNPD/CCNA2 2 GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus 2/566 18/18722 0.101538800347714 0.300365939633239 ATP2B4/SEMA6A 2 GO:1902683 regulation of receptor localization to synapse 2/566 18/18722 0.101538800347714 0.300365939633239 TYROBP/DAG1 2 GO:0001824 blastocyst development 6/566 106/18722 0.102175381086481 0.301647743101467 RPL13/SF3B6/RRM2/PSMC4/CCNB1IP1/RPL7L1 6 GO:0030038 contractile actin filament bundle assembly 6/566 106/18722 0.102175381086481 0.301647743101467 PFN1/ACTG1/STMN1/S100A10/MET/NRP1 6 GO:0043149 stress fiber assembly 6/566 106/18722 0.102175381086481 0.301647743101467 PFN1/ACTG1/STMN1/S100A10/MET/NRP1 6 GO:0046889 positive regulation of lipid biosynthetic process 5/566 82/18722 0.102487287773812 0.302167817992721 CD74/APOE/ANXA1/CGA/RAB38 5 GO:2001057 reactive nitrogen species metabolic process 5/566 82/18722 0.102487287773812 0.302167817992721 DYNLL1/HSP90AB1/ATP2B4/AIF1/HBB 5 GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 7/566 131/18722 0.102637725812844 0.30221108156004 FBN2/FBN1/LRP2/CRIM1/LRP1/GLG1/HTRA1 7 GO:1903844 regulation of cellular response to transforming growth factor beta stimulus 7/566 131/18722 0.102637725812844 0.30221108156004 FBN2/FBN1/HSP90AB1/ENG/GLG1/FOLR1/HTRA1 7 GO:0035306 positive regulation of dephosphorylation 4/566 59/18722 0.102793137338796 0.302268855635613 CALM1/HSP90AB1/PPIA/SLC39A10 4 GO:0071806 protein transmembrane transport 4/566 59/18722 0.102793137338796 0.302268855635613 HSPD1/TOMM22/ABCA1/SEC61A1 4 GO:0048762 mesenchymal cell differentiation 11/566 236/18722 0.103682140306177 0.304681774681914 FN1/LAMA5/HNRNPAB/ISL1/SEMA6D/SEMA3F/NRP1/ENG/DAG1/FOLR1/SEMA6A 11 GO:1902107 positive regulation of leukocyte differentiation 8/566 157/18722 0.104119903747913 0.305564806516616 CD74/HMGB1/HLA-DRB1/TYROBP/ANXA1/HLA-DRA/CD46/ATP6AP1 8 GO:1903708 positive regulation of hemopoiesis 8/566 157/18722 0.104119903747913 0.305564806516616 CD74/HMGB1/HLA-DRB1/TYROBP/ANXA1/HLA-DRA/CD46/ATP6AP1 8 GO:0002685 regulation of leukocyte migration 10/566 210/18722 0.105504008170049 0.308671875653468 CD74/MIF/HMGB1/ANXA1/LGMN/APP/AIF1/DPP4/SERPINE1/CALR 10 GO:0007623 circadian rhythm 10/566 210/18722 0.105504008170049 0.308671875653468 TYMS/EGFR/CDK1/PPP1CA/SLC6A4/IMPDH2/HNRNPD/NAGLU/ZFHX3/ADRB1 10 GO:0019724 B cell mediated immunity 10/566 210/18722 0.105504008170049 0.308671875653468 CD74/HLA-DRB1/FCER1G/HLA-DPA1/HLA-DRA/HLA-DPB1/B2M/HSPD1/CD46/TFRC 10 GO:0050866 negative regulation of cell activation 10/566 210/18722 0.105504008170049 0.308671875653468 CD74/APOE/HMGB1/HLA-DRB1/TYROBP/ANXA1/SERPINE2/GRN/GPNMB/MNDA 10 GO:1901214 regulation of neuron death 14/566 319/18722 0.105754100749839 0.308671875653468 APOE/HSP90AB1/TYROBP/LRP1/ISL1/LGMN/PARK7/HSPD1/NRP1/GRN/SERPINF1/GPNMB/UBE2V2/TMEM259 14 GO:0019318 hexose metabolic process 11/566 237/18722 0.105950852164906 0.308671875653468 GAPDH/HMGB1/TPI1/ALDOA/ENO1/PPP1CA/B4GALT1/IGF2/LRP5/GAA/GLB1 11 GO:0070482 response to oxygen levels 15/566 347/18722 0.106104360027036 0.308671875653468 MALAT1/LDHA/ENO1/CYBA/CCNB1/SLC2A1/SLC6A4/HSPD1/CHCHD2/CCNA2/BNIP3/DPP4/HSP90B1/ATP6AP1/P4HB 15 GO:0055074 calcium ion homeostasis 19/566 460/18722 0.1061115101752 0.308671875653468 TPT1/APOE/HMGB1/CALM1/ATP2B4/LRP1/CYBA/ITGAV/STOML2/GSTO1/BNIP3/APP/HSP90B1/HEXB/SRI/GJA1/ATP2B1/P2RY6/CALR 19 GO:0001825 blastocyst formation 3/566 38/18722 0.106644644473567 0.308671875653468 SF3B6/CCNB1IP1/RPL7L1 3 GO:0007007 inner mitochondrial membrane organization 3/566 38/18722 0.106644644473567 0.308671875653468 HSPA9/GHITM/TIMM9 3 GO:0009309 amine biosynthetic process 3/566 38/18722 0.106644644473567 0.308671875653468 OAZ1/SMS/PARK7 3 GO:0009595 detection of biotic stimulus 3/566 38/18722 0.106644644473567 0.308671875653468 HLA-B/HLA-DRB1/HLA-A 3 GO:0032373 positive regulation of sterol transport 3/566 38/18722 0.106644644473567 0.308671875653468 APOE/LRP1/ABCA1 3 GO:0032376 positive regulation of cholesterol transport 3/566 38/18722 0.106644644473567 0.308671875653468 APOE/LRP1/ABCA1 3 GO:0071392 cellular response to estradiol stimulus 3/566 38/18722 0.106644644473567 0.308671875653468 EGFR/HNRNPD/CCNA2 3 GO:0071398 cellular response to fatty acid 3/566 38/18722 0.106644644473567 0.308671875653468 NME1/CCNB1/NME2 3 GO:1901031 regulation of response to reactive oxygen species 3/566 38/18722 0.106644644473567 0.308671875653468 PARK7/TXN/MET 3 GO:1902110 positive regulation of mitochondrial membrane permeability involved in apoptotic process 3/566 38/18722 0.106644644473567 0.308671875653468 VDAC2/SLC25A5/BNIP3 3 GO:1903580 positive regulation of ATP metabolic process 3/566 38/18722 0.106644644473567 0.308671875653468 ENO1/TMSB4X/APP 3 GO:1903725 regulation of phospholipid metabolic process 3/566 38/18722 0.106644644473567 0.308671875653468 APOC1/STOML2/RAB38 3 GO:2000279 negative regulation of DNA biosynthetic process 3/566 38/18722 0.106644644473567 0.308671875653468 HNRNPA1/HNRNPC/GJA1 3 GO:0048659 smooth muscle cell proliferation 9/566 184/18722 0.106703957014979 0.308671875653468 APOE/CYBA/GSTP1/EGFR/HPGD/AIF1/GNAI3/GJA1/P2RY6 9 GO:0031638 zymogen activation 4/566 60/18722 0.107655853460461 0.311187730937553 ENO1/SERPINE2/LGMN/SERPINE1 4 GO:0016042 lipid catabolic process 14/566 320/18722 0.107713453138987 0.311187730937553 APOC1/APOE/SPP1/LRP1/ETFB/ACAT2/STS/ECHS1/HEXB/ECH1/SLC27A2/ASAH1/HEXA/GM2A 14 GO:0044282 small molecule catabolic process 16/566 376/18722 0.107894005850395 0.311462735488106 APOE/TPI1/ENO1/ATP2B4/ETFB/PARK7/GCSH/ACAT2/IMPA2/MTHFS/ECHS1/LRP5/ECH1/ESD/SLC27A2/GLB1 16 GO:0050807 regulation of synapse organization 10/566 211/18722 0.107948562636601 0.311462735488106 APOE/SRGN/SPARC/SEMA3F/CFL1/DAG1/CDC20/CLSTN1/APP/UBE2V2 10 GO:0046328 regulation of JNK cascade 7/566 133/18722 0.10889180766204 0.313980782196503 HMGB1/DNAJA1/GSTP1/EGFR/APP/IGF1R/COPS5 7 GO:0140013 meiotic nuclear division 9/566 185/18722 0.109349666364223 0.315007910850501 CCNE1/PTTG1/CKS2/RAD51/MND1/CCNB2/CDC20/CCNB1IP1/CALR 9 GO:0035966 response to topologically incorrect protein 8/566 159/18722 0.109834881559594 0.315007910850501 HSP90AB1/DNAJA1/HSPA9/HSPD1/AMFR/HSPE1/EDEM3/COPS5 8 GO:0051170 import into nucleus 8/566 159/18722 0.109834881559594 0.315007910850501 RPL23/HNRNPA1/RAN/HSP90AB1/NUTF2/CDH1/CDK1/TXNIP 8 GO:1903169 regulation of calcium ion transmembrane transport 8/566 159/18722 0.109834881559594 0.315007910850501 CALM1/VDAC1/C4orf3/CYBA/AHNAK/GSTO1/SRI/P2RY6 8 GO:0051403 stress-activated MAPK cascade 11/566 239/18722 0.110574685469067 0.315007910850501 HMGB1/PRDX1/DNAJA1/PPIA/GSTP1/EGFR/PBK/PDCD10/APP/IGF1R/COPS5 11 GO:0032370 positive regulation of lipid transport 5/566 84/18722 0.110611674487754 0.315007910850501 APOE/SPP1/LRP1/TRIAP1/ABCA1 5 GO:0032508 DNA duplex unwinding 5/566 84/18722 0.110611674487754 0.315007910850501 ANXA1/RFC2/RFC3/RAD51/RUVBL1 5 GO:0010959 regulation of metal ion transport 17/566 406/18722 0.111036233433854 0.315007910850501 CALM1/VDAC1/ATP2B4/C4orf3/CYBA/SERPINE2/B2M/AHNAK/ITGB1/AKAP9/GSTO1/GLRX/SRI/GJA1/ATP2B1/PRSS8/P2RY6 17 GO:0000729 DNA double-strand break processing 2/566 19/18722 0.111299964907421 0.315007910850501 UBE2N/UBE2V2 2 GO:0002716 negative regulation of natural killer cell mediated immunity 2/566 19/18722 0.111299964907421 0.315007910850501 HLA-B/HLA-A 2 GO:0002902 regulation of B cell apoptotic process 2/566 19/18722 0.111299964907421 0.315007910850501 CD74/SLC39A10 2 GO:0006007 glucose catabolic process 2/566 19/18722 0.111299964907421 0.315007910850501 ENO1/LRP5 2 GO:0006670 sphingosine metabolic process 2/566 19/18722 0.111299964907421 0.315007910850501 PLPP3/ASAH1 2 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 2/566 19/18722 0.111299964907421 0.315007910850501 RPL26/TRIAP1 2 GO:0007039 protein catabolic process in the vacuole 2/566 19/18722 0.111299964907421 0.315007910850501 LRP2/LRP1 2 GO:0009168 purine ribonucleoside monophosphate biosynthetic process 2/566 19/18722 0.111299964907421 0.315007910850501 IMPDH2/GMPS 2 GO:0010544 negative regulation of platelet activation 2/566 19/18722 0.111299964907421 0.315007910850501 APOE/SERPINE2 2 GO:0033194 response to hydroperoxide 2/566 19/18722 0.111299964907421 0.315007910850501 GPX1/AIF1 2 GO:0034501 protein localization to kinetochore 2/566 19/18722 0.111299964907421 0.315007910850501 CDK1/BUB3 2 GO:0035728 response to hepatocyte growth factor 2/566 19/18722 0.111299964907421 0.315007910850501 LGMN/NRP1 2 GO:0042474 middle ear morphogenesis 2/566 19/18722 0.111299964907421 0.315007910850501 RPL38/NAGLU 2 GO:0045019 negative regulation of nitric oxide biosynthetic process 2/566 19/18722 0.111299964907421 0.315007910850501 DYNLL1/ATP2B4 2 GO:0045947 negative regulation of translational initiation 2/566 19/18722 0.111299964907421 0.315007910850501 RPL13A/EIF3E 2 GO:0046653 tetrahydrofolate metabolic process 2/566 19/18722 0.111299964907421 0.315007910850501 TYMS/MTHFS 2 GO:0046716 muscle cell cellular homeostasis 2/566 19/18722 0.111299964907421 0.315007910850501 ALDOA/GAA 2 GO:0097501 stress response to metal ion 2/566 19/18722 0.111299964907421 0.315007910850501 PARK7/MT2A 2 GO:1900221 regulation of amyloid-beta clearance 2/566 19/18722 0.111299964907421 0.315007910850501 APOE/LRP1 2 GO:1903083 protein localization to condensed chromosome 2/566 19/18722 0.111299964907421 0.315007910850501 CDK1/BUB3 2 GO:1904406 negative regulation of nitric oxide metabolic process 2/566 19/18722 0.111299964907421 0.315007910850501 DYNLL1/ATP2B4 2 GO:0036293 response to decreased oxygen levels 14/566 322/18722 0.111697249807488 0.31593148420771 MALAT1/LDHA/ENO1/CYBA/CCNB1/SLC2A1/SLC6A4/HSPD1/CHCHD2/CCNA2/BNIP3/DPP4/HSP90B1/P4HB 14 GO:0002449 lymphocyte mediated immunity 15/566 350/18722 0.111800573224295 0.31602295364734 CD74/HLA-B/HMGB1/HLA-DRB1/FCER1G/HLA-DPA1/HLA-A/PRDX1/HLA-DRA/HLA-DPB1/TUBB4B/B2M/HSPD1/CD46/TFRC 15 GO:0071706 tumor necrosis factor superfamily cytokine production 9/566 186/18722 0.112031864346755 0.31627511735685 MIF/HMGB1/TYROBP/CYBA/GSTP1/ISL1/HSPD1/APP/GPNMB 9 GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 9/566 186/18722 0.112031864346755 0.31627511735685 MIF/HMGB1/TYROBP/CYBA/GSTP1/ISL1/HSPD1/APP/GPNMB 9 GO:0034113 heterotypic cell-cell adhesion 4/566 61/18722 0.112620355589875 0.31720744502859 ITGAV/ITGB1/DSC2/DSG2 4 GO:0040014 regulation of multicellular organism growth 4/566 61/18722 0.112620355589875 0.31720744502859 LGMN/APP/IGF2/ADRB1 4 GO:0043030 regulation of macrophage activation 4/566 61/18722 0.112620355589875 0.31720744502859 CD74/MIF/HSPD1/GRN 4 GO:0043271 negative regulation of ion transport 8/566 160/18722 0.112755562245498 0.31720744502859 CALM1/VDAC1/C4orf3/SERPINE2/YWHAQ/GSTO1/SRI/SLC43A2 8 GO:0032414 positive regulation of ion transmembrane transporter activity 6/566 109/18722 0.112789396803146 0.31720744502859 CALM1/TMSB4X/AKAP9/GSTO1/GLRX/P2RY6 6 GO:0034314 Arp2/3 complex-mediated actin nucleation 3/566 39/18722 0.113074621576903 0.31720744502859 ARPC2/ARPC5/ARPC1A 3 GO:0045622 regulation of T-helper cell differentiation 3/566 39/18722 0.113074621576903 0.31720744502859 HLA-DRB1/ANXA1/HLA-DRA 3 GO:0046621 negative regulation of organ growth 3/566 39/18722 0.113074621576903 0.31720744502859 SLC6A4/CGA/GJA1 3 GO:1901021 positive regulation of calcium ion transmembrane transporter activity 3/566 39/18722 0.113074621576903 0.31720744502859 CALM1/GSTO1/P2RY6 3 GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation 3/566 39/18722 0.113074621576903 0.31720744502859 HLA-DRB1/ANXA1/HLA-DRA 3 GO:0030433 ubiquitin-dependent ERAD pathway 5/566 85/18722 0.114787545504546 0.321809919764634 AMFR/HSP90B1/CANX/EDEM3/CALR 5 GO:0002687 positive regulation of leukocyte migration 7/566 135/18722 0.115344467559691 0.322761514503926 CD74/HMGB1/LGMN/APP/AIF1/SERPINE1/CALR 7 GO:0042157 lipoprotein metabolic process 7/566 135/18722 0.115344467559691 0.322761514503926 APOC1/APOE/LRP1/ITGAV/ABCA1/CTSD/OLR1 7 GO:0061982 meiosis I cell cycle process 7/566 135/18722 0.115344467559691 0.322761514503926 CCNE1/PTTG1/CKS2/RAD51/MND1/CCNB2/CCNB1IP1 7 GO:0002698 negative regulation of immune effector process 6/566 110/18722 0.116447269453374 0.325438319903593 HLA-B/HLA-A/ANXA1/RPS19/GRN/CD46 6 GO:1905954 positive regulation of lipid localization 6/566 110/18722 0.116447269453374 0.325438319903593 PLIN2/APOE/SPP1/LRP1/TRIAP1/ABCA1 6 GO:0030308 negative regulation of cell growth 9/566 188/18722 0.11750506582589 0.327456833404886 SPP1/ENO1/SERPINE2/SEMA6D/SEMA3F/NRP1/NDUFS3/GJA1/SEMA6A 9 GO:0009116 nucleoside metabolic process 4/566 62/18722 0.117684396551621 0.327456833404886 ERH/TK1/UMPS/DNPH1 4 GO:0010573 vascular endothelial growth factor production 4/566 62/18722 0.117684396551621 0.327456833404886 NUTF2/IL6ST/ISL1/ADGRG1 4 GO:0032615 interleukin-12 production 4/566 62/18722 0.117684396551621 0.327456833404886 HLA-B/HMGB1/ISL1/HSPD1 4 GO:0032655 regulation of interleukin-12 production 4/566 62/18722 0.117684396551621 0.327456833404886 HLA-B/HMGB1/ISL1/HSPD1 4 GO:0032757 positive regulation of interleukin-8 production 4/566 62/18722 0.117684396551621 0.327456833404886 CD74/HMGB1/PARK7/SERPINE1 4 GO:1903078 positive regulation of protein localization to plasma membrane 4/566 62/18722 0.117684396551621 0.327456833404886 ATP2B4/LRP1/EGFR/ITGB1 4 GO:0060562 epithelial tube morphogenesis 14/566 325/18722 0.117835201782013 0.327671654174591 PFN1/LRP2/LAMA5/COL4A1/LGR5/PPP1CA/SPINT1/MET/NRP1/ENG/DAG1/LRP5/PLXNB2/FOLR1 14 GO:0015908 fatty acid transport 5/566 86/18722 0.119037725375374 0.330396479657832 PLIN2/APOE/ANXA1/SLC2A1/SLC27A2 5 GO:0034103 regulation of tissue remodeling 5/566 86/18722 0.119037725375374 0.330396479657832 SPP1/EGFR/GPNMB/ATP6AP1/TFRC 5 GO:1903510 mucopolysaccharide metabolic process 5/566 86/18722 0.119037725375374 0.330396479657832 CHPF/GNS/ITIH5/GLB1/B3GNT3 5 GO:0010863 positive regulation of phospholipase C activity 3/566 40/18722 0.119647928166339 0.330852531799093 FLT1/EGFR/P2RY6 3 GO:0014037 Schwann cell differentiation 3/566 40/18722 0.119647928166339 0.330852531799093 CDK1/DAG1/ITGB4 3 GO:0045429 positive regulation of nitric oxide biosynthetic process 3/566 40/18722 0.119647928166339 0.330852531799093 HSP90AB1/AIF1/HBB 3 GO:0046365 monosaccharide catabolic process 3/566 40/18722 0.119647928166339 0.330852531799093 ENO1/LRP5/GLB1 3 GO:1902686 mitochondrial outer membrane permeabilization involved in programmed cell death 3/566 40/18722 0.119647928166339 0.330852531799093 VDAC2/SLC25A5/BNIP3 3 GO:2000142 regulation of DNA-templated transcription, initiation 3/566 40/18722 0.119647928166339 0.330852531799093 HMGB1/SUB1/MED4 3 GO:0014066 regulation of phosphatidylinositol 3-kinase signaling 6/566 111/18722 0.120164027141201 0.330879377274284 FN1/FLT1/SERPINE2/EGFR/PLXNB1/IGF1R 6 GO:0090288 negative regulation of cellular response to growth factor stimulus 6/566 111/18722 0.120164027141201 0.330879377274284 FBN1/LRP2/CRIM1/ATP2B4/HTRA1/SEMA6A 6 GO:0006448 regulation of translational elongation 2/566 20/18722 0.121292709728578 0.330879377274284 SRP9/EIF4A3 2 GO:0006590 thyroid hormone generation 2/566 20/18722 0.121292709728578 0.330879377274284 CGA/CTSB 2 GO:0006851 mitochondrial calcium ion transmembrane transport 2/566 20/18722 0.121292709728578 0.330879377274284 VDAC1/STOML2 2 GO:0007194 negative regulation of adenylate cyclase activity 2/566 20/18722 0.121292709728578 0.330879377274284 AKAP9/GNAI3 2 GO:0007620 copulation 2/566 20/18722 0.121292709728578 0.330879377274284 SERPINE2/SLC6A4 2 GO:0015669 gas transport 2/566 20/18722 0.121292709728578 0.330879377274284 HBA2/HBB 2 GO:0032211 negative regulation of telomere maintenance via telomerase 2/566 20/18722 0.121292709728578 0.330879377274284 HNRNPA1/HNRNPC 2 GO:0032495 response to muramyl dipeptide 2/566 20/18722 0.121292709728578 0.330879377274284 VIM/CHMP5 2 GO:0032986 protein-DNA complex disassembly 2/566 20/18722 0.121292709728578 0.330879377274284 RPL23/SUPT16H 2 GO:0042359 vitamin D metabolic process 2/566 20/18722 0.121292709728578 0.330879377274284 LRP2/LGMN 2 GO:0043555 regulation of translation in response to stress 2/566 20/18722 0.121292709728578 0.330879377274284 NPM1/PPP1CA 2 GO:0043691 reverse cholesterol transport 2/566 20/18722 0.121292709728578 0.330879377274284 APOE/ABCA1 2 GO:0045063 T-helper 1 cell differentiation 2/566 20/18722 0.121292709728578 0.330879377274284 HMGB1/ANXA1 2 GO:0046931 pore complex assembly 2/566 20/18722 0.121292709728578 0.330879377274284 CCT8/CCT3 2 GO:0048670 regulation of collateral sprouting 2/566 20/18722 0.121292709728578 0.330879377274284 SPP1/LRP1 2 GO:0071397 cellular response to cholesterol 2/566 20/18722 0.121292709728578 0.330879377274284 DAG1/ABCA1 2 GO:1901679 nucleotide transmembrane transport 2/566 20/18722 0.121292709728578 0.330879377274284 SLC25A5/SLC19A1 2 GO:1904292 regulation of ERAD pathway 2/566 20/18722 0.121292709728578 0.330879377274284 UBXN1/TMEM259 2 GO:2000010 positive regulation of protein localization to cell surface 2/566 20/18722 0.121292709728578 0.330879377274284 HSP90AB1/TYROBP 2 GO:2000479 regulation of cAMP-dependent protein kinase activity 2/566 20/18722 0.121292709728578 0.330879377274284 ATP2B4/PKIB 2 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 15/566 355/18722 0.121693903307412 0.331770518998528 FBN2/FBN1/LRP2/CRIM1/VIM/HSP90AB1/LRP1/FSTL1/SUB1/HPGD/ITGB8/ENG/GLG1/FOLR1/HTRA1 15 GO:0002831 regulation of response to biotic stimulus 14/566 327/18722 0.122034870239361 0.332496476319238 APOE/HLA-B/HMGB2/HMGB1/HLA-DRB1/HSP90AB1/TYROBP/HLA-A/CYBA/RPS19/HSPD1/GRN/MNDA/HTRA1 14 GO:0045936 negative regulation of phosphate metabolic process 18/566 441/18722 0.122651221726043 0.33397140007605 NPM1/APOC1/APOE/DYNLL1/CALM1/DNAJA1/PPIA/LRP1/GSTP1/PKIB/CCNB1/PRDX3/PARK7/ENG/PBK/PLPP3/LRP5/FBLN1 18 GO:0016239 positive regulation of macroautophagy 4/566 63/18722 0.12284565767956 0.334296374076651 VDAC1/SLC25A5/BNIP3/GNAI3 4 GO:0042692 muscle cell differentiation 16/566 384/18722 0.122991429779225 0.334354694690384 KRT19/YBX1/ACTG1/CSRP2/MORF4L2/CCNB1/ISL1/CACYBP/CDK1/GPX1/KRT8/ITGB1/ENG/IGF2/PLD3/CALR 16 GO:0051051 negative regulation of transport 19/566 470/18722 0.123017293329481 0.334354694690384 CD74/APOC1/APOE/HMGB1/CALM1/ANXA1/VDAC1/C4orf3/SERPINE2/YWHAQ/OAZ1/PARK7/TXN/ITGAV/GSTO1/LMAN1/SRI/SLC43A2/GJA1 19 GO:0001776 leukocyte homeostasis 5/566 87/18722 0.123361046681243 0.335084429423364 RPS6/CD74/HMGB1/ANXA1/CCNB2 5 GO:0010563 negative regulation of phosphorus metabolic process 18/566 442/18722 0.124481568867061 0.337921917436681 NPM1/APOC1/APOE/DYNLL1/CALM1/DNAJA1/PPIA/LRP1/GSTP1/PKIB/CCNB1/PRDX3/PARK7/ENG/PBK/PLPP3/LRP5/FBLN1 18 GO:0050680 negative regulation of epithelial cell proliferation 8/566 164/18722 0.124853691488006 0.338313228548144 APOE/FLT1/ISL1/SPARC/B2M/PDCD10/SERPINF1/GJA1 8 GO:0050792 regulation of viral process 8/566 164/18722 0.124853691488006 0.338313228548144 CD74/LGALS1/HLA-DRB1/PPIA/BANF1/IFITM2/PPIH/P4HB 8 GO:0050806 positive regulation of synaptic transmission 8/566 164/18722 0.124853691488006 0.338313228548144 APOE/TYROBP/SERPINE2/EGFR/LGMN/CLSTN1/APP/MME 8 GO:1903322 positive regulation of protein modification by small protein conjugation or removal 7/566 138/18722 0.125389023230997 0.339557135902918 NPM1/RPS2/UBE2L3/UBE2N/UBE2S/GABARAP/CDC20 7 GO:0032956 regulation of actin cytoskeleton organization 15/566 357/18722 0.125790320765579 0.340114172162969 PFN1/ACTG1/LRP1/STMN1/TMSB10/PHPT1/S100A10/ARPC2/ARPC5/MET/TMSB4X/NRP1/ARPC1A/IQGAP1/SCIN 15 GO:0045088 regulation of innate immune response 10/566 218/18722 0.125955908527876 0.340114172162969 APOE/HLA-B/HMGB2/HMGB1/HSP90AB1/TYROBP/HLA-A/RPS19/GRN/MNDA 10 GO:0050803 regulation of synapse structure or activity 10/566 218/18722 0.125955908527876 0.340114172162969 APOE/SRGN/SPARC/SEMA3F/CFL1/DAG1/CDC20/CLSTN1/APP/UBE2V2 10 GO:0006164 purine nucleotide biosynthetic process 9/566 191/18722 0.125984072943278 0.340114172162969 ALDOA/ENO1/NME1/SLC26A2/IMPDH2/TMSB4X/STOML2/GMPS/NME2 9 GO:0032733 positive regulation of interleukin-10 production 3/566 41/18722 0.126358679415443 0.340114172162969 HMGB1/HSPD1/CD46 3 GO:0032735 positive regulation of interleukin-12 production 3/566 41/18722 0.126358679415443 0.340114172162969 HMGB1/ISL1/HSPD1 3 GO:0044786 cell cycle DNA replication 3/566 41/18722 0.126358679415443 0.340114172162969 GMNN/RAD51/DBF4 3 GO:0070296 sarcoplasmic reticulum calcium ion transport 3/566 41/18722 0.126358679415443 0.340114172162969 CALM1/GSTO1/SRI 3 GO:1901385 regulation of voltage-gated calcium channel activity 3/566 41/18722 0.126358679415443 0.340114172162969 CALM1/AHNAK/SRI 3 GO:1904407 positive regulation of nitric oxide metabolic process 3/566 41/18722 0.126358679415443 0.340114172162969 HSP90AB1/AIF1/HBB 3 GO:0001843 neural tube closure 5/566 88/18722 0.127756296394381 0.343668297007725 PFN1/LRP2/SPINT1/PLXNB2/FOLR1 5 GO:0006749 glutathione metabolic process 4/566 64/18722 0.128101754456661 0.343766733478634 GSTP1/GPX1/PARK7/GSTO1 4 GO:0030837 negative regulation of actin filament polymerization 4/566 64/18722 0.128101754456661 0.343766733478634 PFN1/TMSB10/TMSB4X/SCIN 4 GO:0045995 regulation of embryonic development 4/566 64/18722 0.128101754456661 0.343766733478634 LAMA5/CDK1/CFL1/DAG1 4 GO:0048857 neural nucleus development 4/566 64/18722 0.128101754456661 0.343766733478634 DYNLL1/CALM1/YWHAQ/NDUFS3 4 GO:1901653 cellular response to peptide 15/566 359/18722 0.129965675056655 0.348252269574266 FBN1/RPL23/VIM/LRP1/PKM/CYBA/GSTP1/LGMN/CHMP5/CCNA2/APP/IGF2/GJA1/ATP2B1/IGF1R 15 GO:0031098 stress-activated protein kinase signaling cascade 11/566 247/18722 0.130209538564683 0.348252269574266 HMGB1/PRDX1/DNAJA1/PPIA/GSTP1/EGFR/PBK/PDCD10/APP/IGF1R/COPS5 11 GO:0030307 positive regulation of cell growth 8/566 166/18722 0.131147954425612 0.348252269574266 FN1/LRP1/CYBA/EGFR/NRP1/MACF1/DNPH1/EXOSC9 8 GO:0043112 receptor metabolic process 8/566 166/18722 0.131147954425612 0.348252269574266 APOE/FCER1G/LRP1/LGMN/CHMP5/ITGB1/ZNRF3/TFRC 8 GO:1902904 negative regulation of supramolecular fiber organization 8/566 166/18722 0.131147954425612 0.348252269574266 PFN1/APOE/STMN1/TMSB10/MET/TMSB4X/PFDN4/SCIN 8 GO:0002689 negative regulation of leukocyte chemotaxis 2/566 21/18722 0.13149417456297 0.348252269574266 MIF/DPP4 2 GO:0006450 regulation of translational fidelity 2/566 21/18722 0.13149417456297 0.348252269574266 RPS5/RPS9 2 GO:0006925 inflammatory cell apoptotic process 2/566 21/18722 0.13149417456297 0.348252269574266 ANXA1/TCP1 2 GO:0007350 blastoderm segmentation 2/566 21/18722 0.13149417456297 0.348252269574266 SEMA3F/NRP1 2 GO:0007617 mating behavior 2/566 21/18722 0.13149417456297 0.348252269574266 APP/HEXB 2 GO:0009127 purine nucleoside monophosphate biosynthetic process 2/566 21/18722 0.13149417456297 0.348252269574266 IMPDH2/GMPS 2 GO:0033962 P-body assembly 2/566 21/18722 0.13149417456297 0.348252269574266 LSM3/LSM4 2 GO:0045655 regulation of monocyte differentiation 2/566 21/18722 0.13149417456297 0.348252269574266 CD74/HLA-DRB1 2 GO:0046519 sphingoid metabolic process 2/566 21/18722 0.13149417456297 0.348252269574266 PLPP3/ASAH1 2 GO:0046823 negative regulation of nucleocytoplasmic transport 2/566 21/18722 0.13149417456297 0.348252269574266 PARK7/TXN 2 GO:0048485 sympathetic nervous system development 2/566 21/18722 0.13149417456297 0.348252269574266 SEMA3F/NRP1 2 GO:0071605 monocyte chemotactic protein-1 production 2/566 21/18722 0.13149417456297 0.348252269574266 HMGB1/GSTP1 2 GO:0071637 regulation of monocyte chemotactic protein-1 production 2/566 21/18722 0.13149417456297 0.348252269574266 HMGB1/GSTP1 2 GO:0097062 dendritic spine maintenance 2/566 21/18722 0.13149417456297 0.348252269574266 APOE/IGF1R 2 GO:1903427 negative regulation of reactive oxygen species biosynthetic process 2/566 21/18722 0.13149417456297 0.348252269574266 PARK7/HSPD1 2 GO:2000178 negative regulation of neural precursor cell proliferation 2/566 21/18722 0.13149417456297 0.348252269574266 SLC6A4/SPINT1 2 GO:2000774 positive regulation of cellular senescence 2/566 21/18722 0.13149417456297 0.348252269574266 EEF1E1/B2M 2 GO:0021987 cerebral cortex development 6/566 114/18722 0.131660677825223 0.348485932032041 LRP1/SLC2A1/ADGRG1/LAMB1/SLC38A2/BNIP3 6 GO:0060606 tube closure 5/566 89/18722 0.132222218026222 0.349764298664729 PFN1/LRP2/SPINT1/PLXNB2/FOLR1 5 GO:0007292 female gamete generation 7/566 140/18722 0.132323999441147 0.349825680232772 RPS6/CCNB1/LGR5/HPGD/CCNB2/HEXB/PAQR7 7 GO:0033002 muscle cell proliferation 11/566 248/18722 0.132790286750286 0.350065318232591 APOE/CYBA/GSTP1/CCNB1/EGFR/CDK1/HPGD/AIF1/GNAI3/GJA1/P2RY6 11 GO:0010939 regulation of necrotic cell death 3/566 42/18722 0.133200954421835 0.350065318232591 YBX3/BNIP3/ASAH1 3 GO:0033574 response to testosterone 3/566 42/18722 0.133200954421835 0.350065318232591 SPP1/NME1/CALR 3 GO:0045047 protein targeting to ER 3/566 42/18722 0.133200954421835 0.350065318232591 SRP9/SRP19/SEC61A1 3 GO:0051602 response to electrical stimulus 3/566 42/18722 0.133200954421835 0.350065318232591 HNRNPD/AKAP9/AIF1 3 GO:0071312 cellular response to alkaloid 3/566 42/18722 0.133200954421835 0.350065318232591 RAD51/CCNA2/AIF1 3 GO:0072595 maintenance of protein localization in organelle 3/566 42/18722 0.133200954421835 0.350065318232591 PARK7/TXN/GJA1 3 GO:0090317 negative regulation of intracellular protein transport 3/566 42/18722 0.133200954421835 0.350065318232591 PARK7/TXN/LMAN1 3 GO:1900274 regulation of phospholipase C activity 3/566 42/18722 0.133200954421835 0.350065318232591 FLT1/EGFR/P2RY6 3 GO:2001222 regulation of neuron migration 3/566 42/18722 0.133200954421835 0.350065318232591 ADGRG1/PLXNB2/SEMA6A 3 GO:0045453 bone resorption 4/566 65/18722 0.13345024202655 0.350513556048496 SPP1/EGFR/ATP6AP1/TFRC 4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules 8/566 167/18722 0.134355261518294 0.352474734401558 CDH1/TENM3/ITGB1/CLSTN1/DSC2/DSC3/PLXNB2/DSG2 8 GO:0034767 positive regulation of ion transmembrane transport 8/566 167/18722 0.134355261518294 0.352474734401558 CALM1/TMSB4X/ITGB1/AKAP9/GSTO1/GLRX/SRI/P2RY6 8 GO:0050777 negative regulation of immune response 9/566 194/18722 0.134780962630685 0.353383301314376 HLA-B/HLA-DRB1/HLA-A/ANXA1/RPS19/GPX1/GRN/CD46/HTRA1 9 GO:0043279 response to alkaloid 6/566 115/18722 0.13560589152439 0.355127899450931 HSP90AB1/SRSF9/HSPD1/RAD51/CCNA2/AIF1 6 GO:0071675 regulation of mononuclear cell migration 6/566 115/18722 0.13560589152439 0.355127899450931 HMGB1/LGMN/APP/AIF1/SERPINE1/CALR 6 GO:0110053 regulation of actin filament organization 12/566 277/18722 0.135859691360887 0.355170852953762 PFN1/ACTG1/STMN1/TMSB10/S100A10/ARPC2/ARPC5/MET/TMSB4X/NRP1/ARPC1A/SCIN 12 GO:0035296 regulation of tube diameter 7/566 141/18722 0.135861626814972 0.355170852953762 APOE/EGFR/SLC6A4/GPX1/GJA1/ATP2B1/ADRB1 7 GO:0097746 blood vessel diameter maintenance 7/566 141/18722 0.135861626814972 0.355170852953762 APOE/EGFR/SLC6A4/GPX1/GJA1/ATP2B1/ADRB1 7 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 5/566 90/18722 0.136757513772873 0.356257724585623 SUMO2/DDA1/GABARAP/CDC20/UBE2V2 5 GO:0034644 cellular response to UV 5/566 90/18722 0.136757513772873 0.356257724585623 NPM1/RPL26/TRIAP1/PBK/MME 5 GO:0035304 regulation of protein dephosphorylation 5/566 90/18722 0.136757513772873 0.356257724585623 CALM1/HSP90AB1/PPIA/HSP90B1/SLC39A10 5 GO:0048477 oogenesis 5/566 90/18722 0.136757513772873 0.356257724585623 RPS6/CCNB1/LGR5/HEXB/PAQR7 5 GO:0070664 negative regulation of leukocyte proliferation 5/566 90/18722 0.136757513772873 0.356257724585623 HLA-DRB1/TYROBP/GSTP1/GPNMB/MNDA 5 GO:1904705 regulation of vascular associated smooth muscle cell proliferation 5/566 90/18722 0.136757513772873 0.356257724585623 GSTP1/HPGD/GNAI3/GJA1/P2RY6 5 GO:0099173 postsynapse organization 8/566 168/18722 0.137602215930766 0.357835438999373 APOE/ACTG1/SRGN/LGMN/SEMA3F/CFL1/NRP1/IGF1R 8 GO:1902806 regulation of cell cycle G1/S phase transition 8/566 168/18722 0.137602215930766 0.357835438999373 RPL26/ANXA1/ATP2B4/EGFR/TRIAP1/CDK2AP2/AIF1/GPNMB 8 GO:0034329 cell junction assembly 17/566 420/18722 0.137604283820064 0.357835438999373 FN1/ACTG1/LRP1/LAMC1/CDH1/ITGA6/S100A10/PLXNB1/NRP1/CLSTN1/ITGB4/APP/IQGAP1/MACF1/GJA1/PLXNB2/UBE2V2 17 GO:0071560 cellular response to transforming growth factor beta stimulus 11/566 250/18722 0.138034567366548 0.358744830073481 FBN2/FBN1/COL4A2/HSP90AB1/HPGD/ITGB8/ENG/PDCD5/GLG1/FOLR1/HTRA1 11 GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 4/566 66/18722 0.138888620571241 0.35991393409963 HMGB2/HMGB1/HSPD1/TFRC 4 GO:0006303 double-strand break repair via nonhomologous end joining 4/566 66/18722 0.138888620571241 0.35991393409963 HMGB2/HMGB1/DEK/PSMD14 4 GO:0016444 somatic cell DNA recombination 4/566 66/18722 0.138888620571241 0.35991393409963 HMGB2/HMGB1/HSPD1/TFRC 4 GO:0042093 T-helper cell differentiation 4/566 66/18722 0.138888620571241 0.35991393409963 HMGB1/HLA-DRB1/ANXA1/HLA-DRA 4 GO:0050766 positive regulation of phagocytosis 4/566 66/18722 0.138888620571241 0.35991393409963 FCER1G/LRP1/CYBA/CALR 4 GO:0035150 regulation of tube size 7/566 142/18722 0.139445324217888 0.360503494517028 APOE/EGFR/SLC6A4/GPX1/GJA1/ATP2B1/ADRB1 7 GO:2000045 regulation of G1/S transition of mitotic cell cycle 7/566 142/18722 0.139445324217888 0.360503494517028 RPL26/ANXA1/EGFR/TRIAP1/CDK2AP2/AIF1/GPNMB 7 GO:0001504 neurotransmitter uptake 3/566 43/18722 0.140168811547389 0.360503494517028 SLC6A4/PARK7/ITGB1 3 GO:0002861 regulation of inflammatory response to antigenic stimulus 3/566 43/18722 0.140168811547389 0.360503494517028 HLA-DRB1/GPX1/PARK7 3 GO:0006284 base-excision repair 3/566 43/18722 0.140168811547389 0.360503494517028 RPS3/HMGB1/RPA3 3 GO:0006509 membrane protein ectodomain proteolysis 3/566 43/18722 0.140168811547389 0.360503494517028 APOE/DAG1/TIMP3 3 GO:0009268 response to pH 3/566 43/18722 0.140168811547389 0.360503494517028 LGMN/SERPINF1/GJA1 3 GO:0035794 positive regulation of mitochondrial membrane permeability 3/566 43/18722 0.140168811547389 0.360503494517028 VDAC2/SLC25A5/BNIP3 3 GO:0042088 T-helper 1 type immune response 3/566 43/18722 0.140168811547389 0.360503494517028 HMGB1/HLA-DRB1/ANXA1 3 GO:0045840 positive regulation of mitotic nuclear division 3/566 43/18722 0.140168811547389 0.360503494517028 ANAPC11/IGF2/LRP5 3 GO:0045981 positive regulation of nucleotide metabolic process 3/566 43/18722 0.140168811547389 0.360503494517028 ENO1/TMSB4X/APP 3 GO:0061383 trabecula morphogenesis 3/566 43/18722 0.140168811547389 0.360503494517028 FBN2/PLXNB1/ENG 3 GO:1900544 positive regulation of purine nucleotide metabolic process 3/566 43/18722 0.140168811547389 0.360503494517028 ENO1/TMSB4X/APP 3 GO:0071674 mononuclear cell migration 9/566 196/18722 0.140818886719482 0.361776418161052 HMGB1/FLT1/ANXA1/RPS19/LGMN/APP/AIF1/SERPINE1/CALR 9 GO:0006937 regulation of muscle contraction 8/566 169/18722 0.140888446483569 0.361776418161052 CALM1/ENO1/AKAP9/GSTO1/DSC2/SRI/ATP2B1/DSG2 8 GO:0002275 myeloid cell activation involved in immune response 5/566 91/18722 0.14136084665441 0.361776418161052 HMGB1/TYROBP/FCER1G/ANXA3/GRN 5 GO:0006354 DNA-templated transcription, elongation 5/566 91/18722 0.14136084665441 0.361776418161052 HMGN1/ALYREF/SUPT16H/CDCA4/GTF2F1 5 GO:0045582 positive regulation of T cell differentiation 5/566 91/18722 0.14136084665441 0.361776418161052 CD74/HLA-DRB1/ANXA1/HLA-DRA/CD46 5 GO:1990874 vascular associated smooth muscle cell proliferation 5/566 91/18722 0.14136084665441 0.361776418161052 GSTP1/HPGD/GNAI3/GJA1/P2RY6 5 GO:0043410 positive regulation of MAPK cascade 19/566 480/18722 0.141444974713155 0.361776418161052 RPS3/CD74/MIF/APOE/HMGB1/HLA-DRB1/FLT1/PPIA/LRP1/EGFR/NRP1/PDCD10/APP/GPNMB/IGF2/IQGAP1/IGF1R/ATP6AP1/P2RY6 19 GO:0007398 ectoderm development 2/566 22/18722 0.141882665343486 0.361776418161052 TPT1/ITGA6 2 GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion 2/566 22/18722 0.141882665343486 0.361776418161052 CALM1/GSTO1 2 GO:0022616 DNA strand elongation 2/566 22/18722 0.141882665343486 0.361776418161052 POLE3/RFC3 2 GO:0032727 positive regulation of interferon-alpha production 2/566 22/18722 0.141882665343486 0.361776418161052 HMGB1/HSPD1 2 GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation 2/566 22/18722 0.141882665343486 0.361776418161052 HMGB1/ANXA1 2 GO:0051220 cytoplasmic sequestering of protein 2/566 22/18722 0.141882665343486 0.361776418161052 TMSB4X/SRI 2 GO:0051412 response to corticosterone 2/566 22/18722 0.141882665343486 0.361776418161052 CALM1/ATP2B1 2 GO:0071359 cellular response to dsRNA 2/566 22/18722 0.141882665343486 0.361776418161052 NPM1/COLEC12 2 GO:0032984 protein-containing complex disassembly 10/566 224/18722 0.142611028392641 0.363425471324578 RPL23/CALM1/STMN1/PPP1CA/CHMP5/CFL1/SUPT16H/BNIP3/SCIN/IGF1R 10 GO:0043967 histone H4 acetylation 4/566 67/18722 0.144414340550331 0.367390082360042 MORF4L2/HAT1/RUVBL1/PIH1D1 4 GO:0046635 positive regulation of alpha-beta T cell activation 4/566 67/18722 0.144414340550331 0.367390082360042 HLA-DRB1/HLA-A/ANXA1/HLA-DRA 4 GO:2000514 regulation of CD4-positive, alpha-beta T cell activation 4/566 67/18722 0.144414340550331 0.367390082360042 HMGB1/HLA-DRB1/ANXA1/HLA-DRA 4 GO:0016485 protein processing 10/566 225/18722 0.145493386652921 0.369923790621818 ENO1/SERPINE2/SRGN/LGMN/BAG2/STOML2/CPD/GLG1/MME/SERPINE1 10 GO:0001655 urogenital system development 14/566 338/18722 0.146650248019723 0.372439762797381 FBN1/LRP2/LAMA5/ANXA1/PSAP/COL4A1/ADAMTS6/LGR5/HPGD/NRP1/SERPINF1/IQGAP1/MME/SEC61A1 14 GO:0018209 peptidyl-serine modification 14/566 338/18722 0.146650248019723 0.372439762797381 MIF/HSP90AB1/ATP2B4/CCNB1/EGFR/CDK1/PARK7/TXN/PDCD10/AKAP9/VRK1/APP/SMG1/TFRC 14 GO:0007179 transforming growth factor beta receptor signaling pathway 9/566 198/18722 0.146992914118163 0.372703274205784 FBN2/FBN1/HSP90AB1/HPGD/ITGB8/ENG/GLG1/FOLR1/HTRA1 9 GO:0009126 purine nucleoside monophosphate metabolic process 3/566 44/18722 0.147256302634316 0.372703274205784 IMPDH2/DNPH1/GMPS 3 GO:0032881 regulation of polysaccharide metabolic process 3/566 44/18722 0.147256302634316 0.372703274205784 HMGB1/PPP1CA/IGF2 3 GO:0046006 regulation of activated T cell proliferation 3/566 44/18722 0.147256302634316 0.372703274205784 RPS3/HMGB1/IGF2 3 GO:0089718 amino acid import across plasma membrane 3/566 44/18722 0.147256302634316 0.372703274205784 ITGB1/SLC43A2/SLC1A5 3 GO:1903214 regulation of protein targeting to mitochondrion 3/566 44/18722 0.147256302634316 0.372703274205784 UBE2L3/PDCD5/LMAN1 3 GO:1903313 positive regulation of mRNA metabolic process 6/566 118/18722 0.147769381946239 0.373691156929885 NCL/CCNB1/HNRNPD/CIRBP/DAZAP1/EXOSC9 6 GO:0032409 regulation of transporter activity 13/566 310/18722 0.147814494014719 0.373691156929885 CALM1/C4orf3/PARK7/AHNAK/TMSB4X/ITGB1/AKAP9/GSTO1/APP/GLRX/SRI/GJA1/P2RY6 13 GO:0002703 regulation of leukocyte mediated immunity 10/566 226/18722 0.148405592548228 0.37497258684717 HLA-B/HMGB1/HLA-DRB1/TYROBP/HLA-A/HLA-DRA/B2M/HSPD1/CD46/TFRC 10 GO:1903532 positive regulation of secretion by cell 12/566 282/18722 0.148591334562754 0.375228940143722 SPP1/DYNLL1/HLA-DRB1/PPIA/LRP1/EGFR/ISL1/PHPT1/SLC6A4/SRI/GJA1/ATP6AP1 12 GO:0006839 mitochondrial transport 11/566 254/18722 0.148849723908209 0.375668350815955 VDAC2/VDAC1/SLC25A5/UBE2L3/HSPD1/STOML2/TOMM22/PDCD5/BNIP3/LMAN1/TIMM9 11 GO:0002697 regulation of immune effector process 14/566 339/18722 0.149013129372349 0.375867678167534 CD74/HLA-B/HMGB1/HLA-DRB1/TYROBP/HLA-A/ANXA1/HLA-DRA/RPS19/B2M/HSPD1/GRN/CD46/TFRC 14 GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response 4/566 68/18722 0.150024807797695 0.377137461499343 HMGB1/HLA-DRB1/ANXA1/HLA-DRA 4 GO:0010812 negative regulation of cell-substrate adhesion 4/566 68/18722 0.150024807797695 0.377137461499343 LGALS1/LRP1/FBLN1/SERPINE1 4 GO:0031640 killing of cells of other organism 4/566 68/18722 0.150024807797695 0.377137461499343 GAPDH/LYZ/HMGN2/RPS19 4 GO:0042267 natural killer cell mediated cytotoxicity 4/566 68/18722 0.150024807797695 0.377137461499343 HLA-B/HLA-A/PRDX1/TUBB4B 4 GO:0046637 regulation of alpha-beta T cell differentiation 4/566 68/18722 0.150024807797695 0.377137461499343 HMGB1/HLA-DRB1/ANXA1/HLA-DRA 4 GO:0060411 cardiac septum morphogenesis 4/566 68/18722 0.150024807797695 0.377137461499343 LRP2/ISL1/NRP1/ENG 4 GO:0006323 DNA packaging 9/566 199/18722 0.15013022409654 0.377189479502141 NPM1/HMGB2/HMGB1/DNAJC9/CCNB1/BANF1/CDK1/ITGB3BP/HAT1 9 GO:0007589 body fluid secretion 5/566 93/18722 0.150766092787392 0.377933921784611 CYBA/NME1/EGFR/UMPS/PRLR 5 GO:0051591 response to cAMP 5/566 93/18722 0.150766092787392 0.377933921784611 LDHA/NME1/SPARC/AKAP9/APP 5 GO:0090398 cellular senescence 5/566 93/18722 0.150766092787392 0.377933921784611 YBX1/EEF1E1/B2M/RSL1D1/CALR 5 GO:0106027 neuron projection organization 5/566 93/18722 0.150766092787392 0.377933921784611 APOE/LGMN/CFL1/APP/IGF1R 5 GO:0046777 protein autophosphorylation 10/566 227/18722 0.151347407859191 0.379177636347282 CALM1/FLT1/EGFR/ENG/VRK1/GPNMB/IQGAP1/NME2/IGF1R/SMG1 10 GO:0006338 chromatin remodeling 11/566 255/18722 0.151620523252791 0.379648239325885 NPM1/HMGB2/HNRNPC/DNAJC9/POLE3/ITGB3BP/HAT1/SUPT16H/SMARCA1/RUVBL1/PIH1D1 11 GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin 2/566 23/18722 0.152437604771801 0.379771805508706 CYBA/MME 2 GO:0006929 substrate-dependent cell migration 2/566 23/18722 0.152437604771801 0.379771805508706 FN1/NRP1 2 GO:0010888 negative regulation of lipid storage 2/566 23/18722 0.152437604771801 0.379771805508706 ITGAV/ABCA1 2 GO:0031280 negative regulation of cyclase activity 2/566 23/18722 0.152437604771801 0.379771805508706 AKAP9/GNAI3 2 GO:0045723 positive regulation of fatty acid biosynthetic process 2/566 23/18722 0.152437604771801 0.379771805508706 CD74/ANXA1 2 GO:0045943 positive regulation of transcription by RNA polymerase I 2/566 23/18722 0.152437604771801 0.379771805508706 NCL/PIH1D1 2 GO:0051457 maintenance of protein location in nucleus 2/566 23/18722 0.152437604771801 0.379771805508706 PARK7/TXN 2 GO:0060575 intestinal epithelial cell differentiation 2/566 23/18722 0.152437604771801 0.379771805508706 IL6ST/TYMS 2 GO:2001169 regulation of ATP biosynthetic process 2/566 23/18722 0.152437604771801 0.379771805508706 ENO1/TMSB4X 2 GO:0070588 calcium ion transmembrane transport 13/566 312/18722 0.152805551724472 0.380475568387779 CALM1/VDAC1/ATP2B4/C4orf3/CYBA/AHNAK/ITGAV/STOML2/GSTO1/SRI/ATP2B1/P2RY6/SEC61A1 13 GO:0072522 purine-containing compound biosynthetic process 9/566 200/18722 0.153300647086503 0.381494958540589 ALDOA/ENO1/NME1/SLC26A2/IMPDH2/TMSB4X/STOML2/GMPS/NME2 9 GO:0045580 regulation of T cell differentiation 7/566 146/18722 0.154229688108749 0.383088985166795 CD74/HMGB1/HLA-DRB1/ANXA1/HLA-DRA/CD46/CLPTM1 7 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 11/566 256/18722 0.154417745049274 0.383088985166795 FBN2/FBN1/LRP2/CRIM1/HSP90AB1/LRP1/FSTL1/ENG/GLG1/FOLR1/HTRA1 11 GO:0030850 prostate gland development 3/566 45/18722 0.154457486157771 0.383088985166795 ANXA1/PSAP/SERPINF1 3 GO:0085029 extracellular matrix assembly 3/566 45/18722 0.154457486157771 0.383088985166795 QSOX1/LAMB1/DAG1 3 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process 3/566 45/18722 0.154457486157771 0.383088985166795 VDAC2/SLC25A5/BNIP3 3 GO:2000273 positive regulation of signaling receptor activity 3/566 45/18722 0.154457486157771 0.383088985166795 PARK7/NRP1/ITGB1 3 GO:0014020 primary neural tube formation 5/566 94/18722 0.155565155298386 0.384500173865264 PFN1/LRP2/SPINT1/PLXNB2/FOLR1 5 GO:1903035 negative regulation of response to wounding 5/566 94/18722 0.155565155298386 0.384500173865264 APOE/SPP1/SERPINE2/GJA1/SERPINE1 5 GO:0002287 alpha-beta T cell activation involved in immune response 4/566 69/18722 0.155717388472388 0.384500173865264 HMGB1/HLA-DRB1/ANXA1/HLA-DRA 4 GO:0002293 alpha-beta T cell differentiation involved in immune response 4/566 69/18722 0.155717388472388 0.384500173865264 HMGB1/HLA-DRB1/ANXA1/HLA-DRA 4 GO:0015807 L-amino acid transport 4/566 69/18722 0.155717388472388 0.384500173865264 SLC38A2/ITGB1/SLC43A2/SLC1A5 4 GO:0033344 cholesterol efflux 4/566 69/18722 0.155717388472388 0.384500173865264 APOC1/APOE/LRP1/ABCA1 4 GO:0045669 positive regulation of osteoblast differentiation 4/566 69/18722 0.155717388472388 0.384500173865264 FBN2/IL6ST/LRP5/ATP6AP1 4 GO:1904377 positive regulation of protein localization to cell periphery 4/566 69/18722 0.155717388472388 0.384500173865264 ATP2B4/LRP1/EGFR/ITGB1 4 GO:0030218 erythrocyte differentiation 6/566 120/18722 0.15614302845411 0.385337451595176 RPS6/HMGB2/SLC25A5/RPS19/B2M/HSPA9 6 GO:0048639 positive regulation of developmental growth 8/566 174/18722 0.157894736298781 0.389444524100927 FN1/YBX3/LRP1/CCNB1/CDK1/NRP1/IGF2/MACF1 8 GO:0032388 positive regulation of intracellular transport 9/566 202/18722 0.159739514901482 0.39355856134001 RAN/HSP90AB1/NUTF2/UBE2L3/CDH1/CDK1/OAZ1/PDCD10/PDCD5 9 GO:1903046 meiotic cell cycle process 9/566 202/18722 0.159739514901482 0.39355856134001 CCNE1/PTTG1/CKS2/RAD51/MND1/CCNB2/CDC20/CCNB1IP1/CALR 9 GO:0043500 muscle adaptation 6/566 121/18722 0.160406552483246 0.39498339140233 ATP2B4/IL6ST/CYBA/DAG1/AIF1/GLRX3 6 GO:0045851 pH reduction 3/566 46/18722 0.161766439372799 0.395156140596439 GRN/ATP6AP1/RAB38 3 GO:0055010 ventricular cardiac muscle tissue morphogenesis 3/566 46/18722 0.161766439372799 0.395156140596439 LRP2/ISL1/ENG 3 GO:0060976 coronary vasculature development 3/566 46/18722 0.161766439372799 0.395156140596439 LRP2/ADAMTS6/NRP1 3 GO:0071827 plasma lipoprotein particle organization 3/566 46/18722 0.161766439372799 0.395156140596439 APOC1/APOE/ABCA1 3 GO:0072599 establishment of protein localization to endoplasmic reticulum 3/566 46/18722 0.161766439372799 0.395156140596439 SRP9/SRP19/SEC61A1 3 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle 3/566 46/18722 0.161766439372799 0.395156140596439 ANXA1/EGFR/AIF1 3 GO:0044839 cell cycle G2/M phase transition 7/566 148/18722 0.161883308002766 0.395156140596439 NPM1/CALM1/CCNB1/CDK1/CCNB2/CCNA2/APP 7 GO:0001783 B cell apoptotic process 2/566 24/18722 0.163139484819464 0.395156140596439 CD74/SLC39A10 2 GO:0001911 negative regulation of leukocyte mediated cytotoxicity 2/566 24/18722 0.163139484819464 0.395156140596439 HLA-B/HLA-A 2 GO:0002021 response to dietary excess 2/566 24/18722 0.163139484819464 0.395156140596439 APOE/ADRB1 2 GO:0002726 positive regulation of T cell cytokine production 2/566 24/18722 0.163139484819464 0.395156140596439 HLA-A/B2M 2 GO:0006213 pyrimidine nucleoside metabolic process 2/566 24/18722 0.163139484819464 0.395156140596439 ERH/TK1 2 GO:0009219 pyrimidine deoxyribonucleotide metabolic process 2/566 24/18722 0.163139484819464 0.395156140596439 TYMS/DUT 2 GO:0010155 regulation of proton transport 2/566 24/18722 0.163139484819464 0.395156140596439 PARK7/TMSB4X 2 GO:0010226 response to lithium ion 2/566 24/18722 0.163139484819464 0.395156140596439 CDH1/CALR 2 GO:0021801 cerebral cortex radial glia-guided migration 2/566 24/18722 0.163139484819464 0.395156140596439 ADGRG1/LAMB1 2 GO:0022030 telencephalon glial cell migration 2/566 24/18722 0.163139484819464 0.395156140596439 ADGRG1/LAMB1 2 GO:0030810 positive regulation of nucleotide biosynthetic process 2/566 24/18722 0.163139484819464 0.395156140596439 ENO1/TMSB4X 2 GO:0033032 regulation of myeloid cell apoptotic process 2/566 24/18722 0.163139484819464 0.395156140596439 ANXA1/TCP1 2 GO:0035458 cellular response to interferon-beta 2/566 24/18722 0.163139484819464 0.395156140596439 IFITM2/MNDA 2 GO:0044321 response to leptin 2/566 24/18722 0.163139484819464 0.395156140596439 LRP2/CCNA2 2 GO:0048641 regulation of skeletal muscle tissue development 2/566 24/18722 0.163139484819464 0.395156140596439 YBX3/IGF2 2 GO:0051000 positive regulation of nitric-oxide synthase activity 2/566 24/18722 0.163139484819464 0.395156140596439 APOE/CALM1 2 GO:0051043 regulation of membrane protein ectodomain proteolysis 2/566 24/18722 0.163139484819464 0.395156140596439 APOE/TIMP3 2 GO:0070935 3'-UTR-mediated mRNA stabilization 2/566 24/18722 0.163139484819464 0.395156140596439 YBX3/HNRNPC 2 GO:0072530 purine-containing compound transmembrane transport 2/566 24/18722 0.163139484819464 0.395156140596439 SLC25A5/SLC19A1 2 GO:0090343 positive regulation of cell aging 2/566 24/18722 0.163139484819464 0.395156140596439 EEF1E1/B2M 2 GO:1900373 positive regulation of purine nucleotide biosynthetic process 2/566 24/18722 0.163139484819464 0.395156140596439 ENO1/TMSB4X 2 GO:1901984 negative regulation of protein acetylation 2/566 24/18722 0.163139484819464 0.395156140596439 PARK7/PIH1D1 2 GO:1903428 positive regulation of reactive oxygen species biosynthetic process 2/566 24/18722 0.163139484819464 0.395156140596439 CYBA/PARK7 2 GO:0015914 phospholipid transport 5/566 96/18722 0.165348798613769 0.400289750640836 APOC1/APOE/ATP10D/TRIAP1/ABCA1 5 GO:0010506 regulation of autophagy 13/566 317/18722 0.16566497902777 0.400837220995451 GAPDH/HMGB1/EEF1A1/VDAC1/QSOX1/SLC25A5/PSAP/PARK7/MET/BNIP3/VPS13C/GNAI3/SMG1 13 GO:0032368 regulation of lipid transport 7/566 149/18722 0.165773278150163 0.400881387465794 APOC1/APOE/SPP1/LRP1/TRIAP1/ITGAV/ABCA1 7 GO:0018108 peptidyl-tyrosine phosphorylation 15/566 375/18722 0.166144859691875 0.401561843294369 CD74/MIF/FLT1/IL6ST/EGFR/ISL1/MET/NRP1/PBK/EFEMP1/APP/IGF2/IQGAP1/PRLR/IGF1R 15 GO:0002228 natural killer cell mediated immunity 4/566 71/18722 0.167338185030287 0.403569664005871 HLA-B/HLA-A/PRDX1/TUBB4B 4 GO:0045824 negative regulation of innate immune response 4/566 71/18722 0.167338185030287 0.403569664005871 HLA-B/HLA-A/RPS19/GRN 4 GO:0050795 regulation of behavior 4/566 71/18722 0.167338185030287 0.403569664005871 APOE/GJA1/ZFHX3/ADRB1 4 GO:0050818 regulation of coagulation 4/566 71/18722 0.167338185030287 0.403569664005871 APOE/SERPINE2/ANXA5/SERPINE1 4 GO:0030324 lung development 8/566 177/18722 0.168542973881933 0.404499035371492 LAMA5/HMGB1/EGFR/PTGES3/SPARC/PPP1CA/DAG1/MME 8 GO:0043405 regulation of MAP kinase activity 8/566 177/18722 0.168542973881933 0.404499035371492 RPS3/APOE/FLT1/DNAJA1/GSTP1/EGFR/PDCD10/IQGAP1 8 GO:0071453 cellular response to oxygen levels 8/566 177/18722 0.168542973881933 0.404499035371492 MALAT1/ENO1/CCNB1/CHCHD2/CCNA2/BNIP3/ATP6AP1/P4HB 8 GO:0071466 cellular response to xenobiotic stimulus 8/566 177/18722 0.168542973881933 0.404499035371492 GSTP1/NME1/EGFR/UMPS/GSTO1/ABCA1/NUDT15/TFRC 8 GO:0051321 meiotic cell cycle 11/566 261/18722 0.16879285254788 0.404499035371492 CCNE1/BUB3/PTTG1/CKS2/RAD51/MND1/CCNB2/CDC20/CCNB1IP1/TUBGCP2/CALR 11 GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal 3/566 47/18722 0.169177269510718 0.404499035371492 CYBA/MME/ADRB1 3 GO:0007595 lactation 3/566 47/18722 0.169177269510718 0.404499035371492 NME1/UMPS/PRLR 3 GO:0010712 regulation of collagen metabolic process 3/566 47/18722 0.169177269510718 0.404499035371492 VIM/ITGB1/ENG 3 GO:0045581 negative regulation of T cell differentiation 3/566 47/18722 0.169177269510718 0.404499035371492 CD74/HMGB1/ANXA1 3 GO:0045646 regulation of erythrocyte differentiation 3/566 47/18722 0.169177269510718 0.404499035371492 HMGB2/B2M/HSPA9 3 GO:0048483 autonomic nervous system development 3/566 47/18722 0.169177269510718 0.404499035371492 FN1/SEMA3F/NRP1 3 GO:0048512 circadian behavior 3/566 47/18722 0.169177269510718 0.404499035371492 NAGLU/ZFHX3/ADRB1 3 GO:0050798 activated T cell proliferation 3/566 47/18722 0.169177269510718 0.404499035371492 RPS3/HMGB1/IGF2 3 GO:0097028 dendritic cell differentiation 3/566 47/18722 0.169177269510718 0.404499035371492 HLA-B/HMGB1/ITGB8 3 GO:0101023 vascular endothelial cell proliferation 3/566 47/18722 0.169177269510718 0.404499035371492 HMGB1/FLT1/IGF2 3 GO:1905562 regulation of vascular endothelial cell proliferation 3/566 47/18722 0.169177269510718 0.404499035371492 HMGB1/FLT1/IGF2 3 GO:0010596 negative regulation of endothelial cell migration 5/566 97/18722 0.170330350334046 0.406600922084275 APOE/HMGB1/ATP2B4/PDCD10/SERPINF1 5 GO:0070252 actin-mediated cell contraction 5/566 97/18722 0.170330350334046 0.406600922084275 AKAP9/DSC2/SRI/GJA1/DSG2 5 GO:0120162 positive regulation of cold-induced thermogenesis 5/566 97/18722 0.170330350334046 0.406600922084275 PRLR/FH/GJA1/IGF1R/ADRB1 5 GO:0008202 steroid metabolic process 13/566 319/18722 0.170958372029214 0.407881389214395 LRP2/APOC1/APOE/SPP1/LGMN/CGA/STS/ABCA1/APP/LRP5/PRLR/SLC27A2/ASAH1 13 GO:0035265 organ growth 8/566 178/18722 0.172163660085672 0.409362390810428 YBX3/PSAP/CCNB1/CDK1/SLC6A4/CGA/IGF2/GJA1 8 GO:0042246 tissue regeneration 4/566 72/18722 0.173260977325925 0.409362390810428 ANXA1/CCNB1/GPX1/DAG1 4 GO:0018212 peptidyl-tyrosine modification 15/566 378/18722 0.173460230005731 0.409362390810428 CD74/MIF/FLT1/IL6ST/EGFR/ISL1/MET/NRP1/PBK/EFEMP1/APP/IGF2/IQGAP1/PRLR/IGF1R 15 GO:0010508 positive regulation of autophagy 6/566 124/18722 0.173492541077283 0.409362390810428 HMGB1/VDAC1/SLC25A5/PARK7/BNIP3/GNAI3 6 GO:0030902 hindbrain development 7/566 151/18722 0.173676212615081 0.409362390810428 SERPINE2/SLC6A4/PSMG1/HNRNPD/ITGB1/AIF1/NAGLU 7 GO:0043535 regulation of blood vessel endothelial cell migration 7/566 151/18722 0.173676212615081 0.409362390810428 APOE/HMGB1/ANXA1/ATP2B4/TMSB4X/NRP1/PDCD10 7 GO:0071456 cellular response to hypoxia 7/566 151/18722 0.173676212615081 0.409362390810428 MALAT1/ENO1/CCNB1/CHCHD2/CCNA2/BNIP3/P4HB 7 GO:1904064 positive regulation of cation transmembrane transport 7/566 151/18722 0.173676212615081 0.409362390810428 CALM1/TMSB4X/AKAP9/GSTO1/GLRX/SRI/P2RY6 7 GO:0003071 renal system process involved in regulation of systemic arterial blood pressure 2/566 25/18722 0.173969821072176 0.409362390810428 CYBA/GJA1 2 GO:0003094 glomerular filtration 2/566 25/18722 0.173969821072176 0.409362390810428 CYBA/GJA1 2 GO:0006312 mitotic recombination 2/566 25/18722 0.173969821072176 0.409362390810428 TPRKB/RAD51 2 GO:0010447 response to acidic pH 2/566 25/18722 0.173969821072176 0.409362390810428 LGMN/SERPINF1 2 GO:0010954 positive regulation of protein processing 2/566 25/18722 0.173969821072176 0.409362390810428 ENO1/BAG2 2 GO:0036315 cellular response to sterol 2/566 25/18722 0.173969821072176 0.409362390810428 DAG1/ABCA1 2 GO:0051291 protein heterooligomerization 2/566 25/18722 0.173969821072176 0.409362390810428 KRT10/RRM2 2 GO:0051450 myoblast proliferation 2/566 25/18722 0.173969821072176 0.409362390810428 MALAT1/GPX1 2 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter 2/566 25/18722 0.173969821072176 0.409362390810428 SUB1/MED4 2 GO:0060706 cell differentiation involved in embryonic placenta development 2/566 25/18722 0.173969821072176 0.409362390810428 KRT19/KRT8 2 GO:0061436 establishment of skin barrier 2/566 25/18722 0.173969821072176 0.409362390810428 STMN1/MET 2 GO:0071459 protein localization to chromosome, centromeric region 2/566 25/18722 0.173969821072176 0.409362390810428 CDK1/BUB3 2 GO:0090330 regulation of platelet aggregation 2/566 25/18722 0.173969821072176 0.409362390810428 IL6ST/SERPINE2 2 GO:1903901 negative regulation of viral life cycle 2/566 25/18722 0.173969821072176 0.409362390810428 PPIA/IFITM2 2 GO:1903959 regulation of anion transmembrane transport 2/566 25/18722 0.173969821072176 0.409362390810428 ITGB1/SLC43A2 2 GO:1904754 positive regulation of vascular associated smooth muscle cell migration 2/566 25/18722 0.173969821072176 0.409362390810428 LRP1/IQGAP1 2 GO:1905048 regulation of metallopeptidase activity 2/566 25/18722 0.173969821072176 0.409362390810428 LRP1/TIMP3 2 GO:1905564 positive regulation of vascular endothelial cell proliferation 2/566 25/18722 0.173969821072176 0.409362390810428 HMGB1/IGF2 2 GO:0003333 amino acid transmembrane transport 5/566 98/18722 0.1753696603011 0.412220553147042 SLC38A2/ITGB1/SLC38A10/SLC43A2/SLC1A5 5 GO:0043502 regulation of muscle adaptation 5/566 98/18722 0.1753696603011 0.412220553147042 ATP2B4/IL6ST/DAG1/AIF1/GLRX3 5 GO:0007626 locomotory behavior 8/566 179/18722 0.175819153026363 0.413059033917343 APOE/PARK7/APP/DPP4/GAA/HEXB/NAGLU/ZFHX3 8 GO:0045930 negative regulation of mitotic cell cycle 10/566 235/18722 0.175916517798442 0.413069798121659 RPL26/MAD2L1/CCNB1/EGFR/CDK1/BUB3/TRIAP1/CDK2AP2/ZWINT/GPNMB 10 GO:0002673 regulation of acute inflammatory response 3/566 48/18722 0.176684124077461 0.413563470238094 IL6ST/GSTP1/PARK7 3 GO:0015804 neutral amino acid transport 3/566 48/18722 0.176684124077461 0.413563470238094 SLC38A2/SLC43A2/SLC1A5 3 GO:0030261 chromosome condensation 3/566 48/18722 0.176684124077461 0.413563470238094 CCNB1/BANF1/CDK1 3 GO:0120009 intermembrane lipid transfer 3/566 48/18722 0.176684124077461 0.413563470238094 APOE/TRIAP1/ABCA1 3 GO:1903053 regulation of extracellular matrix organization 3/566 48/18722 0.176684124077461 0.413563470238094 LRP1/DAG1/DPP4 3 GO:1905710 positive regulation of membrane permeability 3/566 48/18722 0.176684124077461 0.413563470238094 VDAC2/SLC25A5/BNIP3 3 GO:0006325 chromatin organization 16/566 409/18722 0.177629337426518 0.415257789367513 NPM1/HMGB2/HMGB1/HMGN2/HMGN1/HNRNPC/DNAJC9/DEK/POLE3/ITGB3BP/HAT1/SUPT16H/SMARCA1/RUVBL1/PIH1D1/MKI67 16 GO:0016573 histone acetylation 7/566 152/18722 0.177687800706449 0.415257789367513 MORF4L2/ISL1/PARK7/POLE3/HAT1/RUVBL1/PIH1D1 7 GO:0051092 positive regulation of NF-kappaB transcription factor activity 7/566 152/18722 0.177687800706449 0.415257789367513 NPM1/RPS3/PPIA/UBE2N/PRDX3/APP/TFRC 7 GO:0055007 cardiac muscle cell differentiation 6/566 125/18722 0.177949727501041 0.415433763416168 CCNB1/ISL1/CACYBP/CDK1/ITGB1/CALR 6 GO:0071621 granulocyte chemotaxis 6/566 125/18722 0.177949727501041 0.415433763416168 CD74/CSF3R/FCER1G/ANXA1/PPIA/DPP4 6 GO:0048738 cardiac muscle tissue development 10/566 236/18722 0.179112729191905 0.417929701447779 LRP2/CCNB1/ISL1/CACYBP/CDK1/ITGB1/ENG/GJA1/DSG2/CALR 10 GO:1904427 positive regulation of calcium ion transmembrane transport 4/566 73/18722 0.179255044720828 0.418042671082833 CALM1/GSTO1/SRI/P2RY6 4 GO:0007033 vacuole organization 8/566 180/18722 0.179508937316666 0.418196645177289 CHMP5/GRN/GABARAP/ABCA1/GAA/HEXB/TMEM41B/NAGLU 8 GO:0010721 negative regulation of cell development 8/566 180/18722 0.179508937316666 0.418196645177289 FBN1/SPP1/B2M/SEMA6D/SEMA3F/NRP1/FBLN1/SEMA6A 8 GO:0030838 positive regulation of actin filament polymerization 5/566 99/18722 0.180465153351488 0.420204426109219 PFN1/ARPC2/ARPC5/ARPC1A/SCIN 5 GO:0002443 leukocyte mediated immunity 17/566 440/18722 0.181249969645458 0.421811220523565 CD74/HLA-B/HMGB1/HLA-DRB1/TYROBP/FCER1G/HLA-DPA1/HLA-A/PRDX1/HLA-DRA/HLA-DPB1/TUBB4B/B2M/ANXA3/HSPD1/CD46/TFRC 17 GO:2001235 positive regulation of apoptotic signaling pathway 6/566 126/18722 0.182452821163398 0.424388693740569 RPS3/RPL26/RPL11/PPP1CA/PARK7/TIMP3 6 GO:0030323 respiratory tube development 8/566 181/18722 0.183232486516275 0.42521914080483 LAMA5/HMGB1/EGFR/PTGES3/SPARC/PPP1CA/DAG1/MME 8 GO:1905952 regulation of lipid localization 8/566 181/18722 0.183232486516275 0.42521914080483 PLIN2/APOC1/APOE/SPP1/LRP1/TRIAP1/ITGAV/ABCA1 8 GO:0007015 actin filament organization 17/566 441/18722 0.183599447746001 0.42521914080483 PFN1/ACTG1/ALDOA/STMN1/TMSB10/MARCKS/S100A10/ARPC2/ARPC5/CFL1/MET/TMSB4X/NRP1/ARPC1A/AIF1/HSP90B1/SCIN 17 GO:0002762 negative regulation of myeloid leukocyte differentiation 3/566 49/18722 0.184281200303878 0.42521914080483 FBN1/NME1/NME2 3 GO:0007622 rhythmic behavior 3/566 49/18722 0.184281200303878 0.42521914080483 NAGLU/ZFHX3/ADRB1 3 GO:0014075 response to amine 3/566 49/18722 0.184281200303878 0.42521914080483 CALM1/NME1/CDK1 3 GO:0030195 negative regulation of blood coagulation 3/566 49/18722 0.184281200303878 0.42521914080483 APOE/SERPINE2/SERPINE1 3 GO:0038084 vascular endothelial growth factor signaling pathway 3/566 49/18722 0.184281200303878 0.42521914080483 FLT1/NRP1/SEMA6A 3 GO:0042304 regulation of fatty acid biosynthetic process 3/566 49/18722 0.184281200303878 0.42521914080483 CD74/APOC1/ANXA1 3 GO:0043457 regulation of cellular respiration 3/566 49/18722 0.184281200303878 0.42521914080483 PARK7/COX7A2L/BNIP3 3 GO:0046580 negative regulation of Ras protein signal transduction 3/566 49/18722 0.184281200303878 0.42521914080483 STMN1/MET/ITGB1 3 GO:0001963 synaptic transmission, dopaminergic 2/566 26/18722 0.18491110884954 0.42521914080483 SLC6A4/PARK7 2 GO:0002407 dendritic cell chemotaxis 2/566 26/18722 0.18491110884954 0.42521914080483 HMGB1/CALR 2 GO:0045672 positive regulation of osteoclast differentiation 2/566 26/18722 0.18491110884954 0.42521914080483 TYROBP/ATP6AP1 2 GO:0046639 negative regulation of alpha-beta T cell differentiation 2/566 26/18722 0.18491110884954 0.42521914080483 HMGB1/ANXA1 2 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway 2/566 26/18722 0.18491110884954 0.42521914080483 RPS3/SLC39A10 2 GO:0060037 pharyngeal system development 2/566 26/18722 0.18491110884954 0.42521914080483 ISL1/FOLR1 2 GO:0060352 cell adhesion molecule production 2/566 26/18722 0.18491110884954 0.42521914080483 PPIA/COLEC12 2 GO:0060669 embryonic placenta morphogenesis 2/566 26/18722 0.18491110884954 0.42521914080483 SPINT1/IGF2 2 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway 2/566 26/18722 0.18491110884954 0.42521914080483 ATP2B4/ADRB1 2 GO:0097205 renal filtration 2/566 26/18722 0.18491110884954 0.42521914080483 CYBA/GJA1 2 GO:1904353 regulation of telomere capping 2/566 26/18722 0.18491110884954 0.42521914080483 PKIB/HNRNPD 2 GO:0051881 regulation of mitochondrial membrane potential 4/566 74/18722 0.185317624008058 0.425714170321917 PRDX3/PARK7/STOML2/BNIP3 4 GO:0070972 protein localization to endoplasmic reticulum 4/566 74/18722 0.185317624008058 0.425714170321917 SRP9/SRP19/GJA1/SEC61A1 4 GO:0051259 protein complex oligomerization 10/566 238/18722 0.185585163641589 0.425738804769105 CD74/MIF/HLA-DRB1/ALDOA/B2M/TK1/KRT10/RRM2/STOML2/SLC1A5 10 GO:0006664 glycolipid metabolic process 5/566 100/18722 0.185615233615641 0.425738804769105 ITGB8/HEXB/GLB1/HEXA/GM2A 5 GO:0009062 fatty acid catabolic process 5/566 100/18722 0.185615233615641 0.425738804769105 ETFB/ACAT2/ECHS1/ECH1/SLC27A2 5 GO:0015711 organic anion transport 14/566 354/18722 0.186841252938805 0.428171735165107 LRP2/ANXA1/SLC25A5/PSAP/SLC2A1/SLC26A2/SLC19A1/SLC38A2/ITGB1/SLC52A1/SLC43A2/GJA1/FOLR1/SLC1A5 14 GO:0032412 regulation of ion transmembrane transporter activity 11/566 267/18722 0.186868302207054 0.428171735165107 CALM1/C4orf3/AHNAK/TMSB4X/ITGB1/AKAP9/GSTO1/APP/GLRX/SRI/P2RY6 11 GO:0060401 cytosolic calcium ion transport 8/566 182/18722 0.186989263491885 0.428228498490676 CALM1/VDAC1/ATP2B4/CYBA/GSTO1/SRI/ATP2B1/P2RY6 8 GO:0006606 protein import into nucleus 7/566 155/18722 0.189954492851477 0.434795579524306 RPL23/RAN/HSP90AB1/NUTF2/CDH1/CDK1/TXNIP 7 GO:1903509 liposaccharide metabolic process 5/566 101/18722 0.190818286436837 0.436548309977799 ITGB8/HEXB/GLB1/HEXA/GM2A 5 GO:0006024 glycosaminoglycan biosynthetic process 4/566 75/18722 0.191445938840879 0.437085804984408 CHPF/HS6ST2/B3GNT3/HEXA 4 GO:0033077 T cell differentiation in thymus 4/566 75/18722 0.191445938840879 0.437085804984408 RPS6/CD74/B2M/CLPTM1 4 GO:0045913 positive regulation of carbohydrate metabolic process 4/566 75/18722 0.191445938840879 0.437085804984408 HMGB1/APP/IGF2/P2RY6 4 GO:2001259 positive regulation of cation channel activity 4/566 75/18722 0.191445938840879 0.437085804984408 CALM1/TMSB4X/GSTO1/P2RY6 4 GO:0007080 mitotic metaphase plate congression 3/566 50/18722 0.191962753795675 0.437368566989941 CCNB1/NUDC/CHMP5 3 GO:0046638 positive regulation of alpha-beta T cell differentiation 3/566 50/18722 0.191962753795675 0.437368566989941 HLA-DRB1/ANXA1/HLA-DRA 3 GO:0071825 protein-lipid complex subunit organization 3/566 50/18722 0.191962753795675 0.437368566989941 APOC1/APOE/ABCA1 3 GO:1900047 negative regulation of hemostasis 3/566 50/18722 0.191962753795675 0.437368566989941 APOE/SERPINE2/SERPINE1 3 GO:0032886 regulation of microtubule-based process 10/566 240/18722 0.192162081149958 0.437481434613452 NPM1/RPS3/STMN1/SKA2/CHMP5/CDK2AP2/MET/AKAP9/MACF1/CLIP1 10 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 14/566 356/18722 0.192208824371948 0.437481434613452 CD74/HLA-B/HMGB1/HLA-DRB1/FCER1G/HLA-DPA1/HLA-A/ANXA1/HLA-DRA/HLA-DPB1/B2M/HSPD1/CD46/TFRC 14 GO:2001257 regulation of cation channel activity 8/566 184/18722 0.194600300950957 0.442654955629016 CALM1/AHNAK/TMSB4X/ITGB1/GSTO1/APP/SRI/P2RY6 8 GO:0030111 regulation of Wnt signaling pathway 13/566 328/18722 0.195792463460327 0.442654955629016 APOE/LRP1/EGFR/ISL1/LGR5/PPP1CA/AMFR/APP/PLPP3/MACF1/RUVBL1/FOLR1/ZNRF3 13 GO:0000469 cleavage involved in rRNA processing 2/566 27/18722 0.195946781034944 0.442654955629016 NHP2/EXOSC9 2 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling 2/566 27/18722 0.195946781034944 0.442654955629016 CALM1/GSTO1 2 GO:0018126 protein hydroxylation 2/566 27/18722 0.195946781034944 0.442654955629016 P3H1/P4HB 2 GO:0032781 positive regulation of ATPase activity 2/566 27/18722 0.195946781034944 0.442654955629016 PFN1/DNAJC9 2 GO:0032967 positive regulation of collagen biosynthetic process 2/566 27/18722 0.195946781034944 0.442654955629016 VIM/ENG 2 GO:0033561 regulation of water loss via skin 2/566 27/18722 0.195946781034944 0.442654955629016 STMN1/MET 2 GO:0042403 thyroid hormone metabolic process 2/566 27/18722 0.195946781034944 0.442654955629016 CGA/CTSB 2 GO:0046174 polyol catabolic process 2/566 27/18722 0.195946781034944 0.442654955629016 TPI1/IMPA2 2 GO:1902914 regulation of protein polyubiquitination 2/566 27/18722 0.195946781034944 0.442654955629016 PPIA/GABARAP 2 GO:1903319 positive regulation of protein maturation 2/566 27/18722 0.195946781034944 0.442654955629016 ENO1/BAG2 2 GO:1904357 negative regulation of telomere maintenance via telomere lengthening 2/566 27/18722 0.195946781034944 0.442654955629016 HNRNPA1/HNRNPC 2 GO:0001841 neural tube formation 5/566 102/18722 0.196072680256159 0.442654955629016 PFN1/LRP2/SPINT1/PLXNB2/FOLR1 5 GO:0010522 regulation of calcium ion transport into cytosol 5/566 102/18722 0.196072680256159 0.442654955629016 CALM1/CYBA/GSTO1/SRI/P2RY6 5 GO:0035710 CD4-positive, alpha-beta T cell activation 5/566 102/18722 0.196072680256159 0.442654955629016 HMGB1/HLA-DRB1/ANXA1/HLA-DRA/STOML2 5 GO:0014823 response to activity 4/566 76/18722 0.197637203619372 0.445734969864967 COL4A2/CYBA/CDK1/HSPD1 4 GO:0043536 positive regulation of blood vessel endothelial cell migration 4/566 76/18722 0.197637203619372 0.445734969864967 HMGB1/ANXA1/TMSB4X/NRP1 4 GO:0051250 negative regulation of lymphocyte activation 7/566 157/18722 0.198318168207234 0.447044296130939 CD74/HMGB1/HLA-DRB1/TYROBP/ANXA1/GPNMB/MNDA 7 GO:0010874 regulation of cholesterol efflux 3/566 51/18722 0.199723106428347 0.449528447835694 APOE/LRP1/ABCA1 3 GO:0045104 intermediate filament cytoskeleton organization 3/566 51/18722 0.199723106428347 0.449528447835694 VIM/KRT18/MACF1 3 GO:0060043 regulation of cardiac muscle cell proliferation 3/566 51/18722 0.199723106428347 0.449528447835694 CCNB1/CDK1/GJA1 3 GO:0010876 lipid localization 17/566 448/18722 0.200466222827639 0.450973028816903 PLIN2/APOC1/APOE/SPP1/ANXA1/LRP1/PSAP/ATP10D/SLC2A1/TRIAP1/ITGAV/STOML2/ABCA1/HEXB/SLC27A2/LRP10/GM2A 17 GO:0007098 centrosome cycle 6/566 130/18722 0.200903260981351 0.451727938327765 NPM1/RANBP1/CDK1/HAUS1/CHMP5/HAUS8 6 GO:0003279 cardiac septum development 5/566 103/18722 0.201376768461885 0.45210760120641 LRP2/ADAMTS6/ISL1/NRP1/ENG 5 GO:0019395 fatty acid oxidation 5/566 103/18722 0.201376768461885 0.45210760120641 ETFB/ACAT2/ECHS1/ECH1/SLC27A2 5 GO:0030593 neutrophil chemotaxis 5/566 103/18722 0.201376768461885 0.45210760120641 CD74/CSF3R/FCER1G/PPIA/DPP4 5 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 8/566 186/18722 0.202337552601329 0.454035677510644 GAPDH/CD74/LGALS1/HLA-DRB1/UBE2N/TFG/GJA1/TFRC 8 GO:0018393 internal peptidyl-lysine acetylation 7/566 158/18722 0.202553488764853 0.454291250368325 MORF4L2/ISL1/PARK7/POLE3/HAT1/RUVBL1/PIH1D1 7 GO:0006367 transcription initiation from RNA polymerase II promoter 4/566 77/18722 0.203888627224364 0.456825449623991 HMGB1/SUB1/MED4/GTF2F1 4 GO:0031016 pancreas development 4/566 77/18722 0.203888627224364 0.456825449623991 ANXA1/ISL1/MET/IGF2 4 GO:0072001 renal system development 12/566 302/18722 0.205339085551109 0.45858174765108 FBN1/LRP2/LAMA5/COL4A1/ADAMTS6/LGR5/HPGD/NRP1/SERPINF1/IQGAP1/MME/SEC61A1 12 GO:1904950 negative regulation of establishment of protein localization 6/566 131/18722 0.205620006669439 0.45858174765108 APOE/ANXA1/DNAJA1/PARK7/TXN/LMAN1 6 GO:0046942 carboxylic acid transport 11/566 273/18722 0.205791377649084 0.45858174765108 LRP2/ANXA1/PSAP/SLC26A2/SLC19A1/SLC38A2/ITGB1/SLC43A2/GJA1/FOLR1/SLC1A5 11 GO:0002695 negative regulation of leukocyte activation 8/566 187/18722 0.206252062703828 0.45858174765108 CD74/HMGB1/HLA-DRB1/TYROBP/ANXA1/GRN/GPNMB/MNDA 8 GO:0032963 collagen metabolic process 5/566 104/18722 0.20672889120191 0.45858174765108 VIM/ITGB1/ENG/P3H1/CTSB 5 GO:0045621 positive regulation of lymphocyte differentiation 5/566 104/18722 0.20672889120191 0.45858174765108 CD74/HLA-DRB1/ANXA1/HLA-DRA/CD46 5 GO:0046634 regulation of alpha-beta T cell activation 5/566 104/18722 0.20672889120191 0.45858174765108 HMGB1/HLA-DRB1/HLA-A/ANXA1/HLA-DRA 5 GO:1901890 positive regulation of cell junction assembly 5/566 104/18722 0.20672889120191 0.45858174765108 S100A10/NRP1/CLSTN1/IQGAP1/UBE2V2 5 GO:0002507 tolerance induction 2/566 28/18722 0.207061167552577 0.45858174765108 HLA-B/HMGB1 2 GO:0002675 positive regulation of acute inflammatory response 2/566 28/18722 0.207061167552577 0.45858174765108 IL6ST/PARK7 2 GO:0006972 hyperosmotic response 2/566 28/18722 0.207061167552577 0.45858174765108 YBX3/SLC2A1 2 GO:0010575 positive regulation of vascular endothelial growth factor production 2/566 28/18722 0.207061167552577 0.45858174765108 IL6ST/ISL1 2 GO:0010714 positive regulation of collagen metabolic process 2/566 28/18722 0.207061167552577 0.45858174765108 VIM/ENG 2 GO:0019098 reproductive behavior 2/566 28/18722 0.207061167552577 0.45858174765108 APP/HEXB 2 GO:0032607 interferon-alpha production 2/566 28/18722 0.207061167552577 0.45858174765108 HMGB1/HSPD1 2 GO:0032647 regulation of interferon-alpha production 2/566 28/18722 0.207061167552577 0.45858174765108 HMGB1/HSPD1 2 GO:0034123 positive regulation of toll-like receptor signaling pathway 2/566 28/18722 0.207061167552577 0.45858174765108 HMGB1/CYBA 2 GO:0090200 positive regulation of release of cytochrome c from mitochondria 2/566 28/18722 0.207061167552577 0.45858174765108 PDCD5/BNIP3 2 GO:0090344 negative regulation of cell aging 2/566 28/18722 0.207061167552577 0.45858174765108 MIF/YBX1 2 GO:1903672 positive regulation of sprouting angiogenesis 2/566 28/18722 0.207061167552577 0.45858174765108 HMGB1/PKM 2 GO:1903779 regulation of cardiac conduction 2/566 28/18722 0.207061167552577 0.45858174765108 ATP2B4/ATP2B1 2 GO:1990776 response to angiotensin 2/566 28/18722 0.207061167552577 0.45858174765108 CYBA/IQGAP1 2 GO:0002218 activation of innate immune response 3/566 52/18722 0.207556653530307 0.45858174765108 HMGB1/TYROBP/MNDA 3 GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum 3/566 52/18722 0.207556653530307 0.45858174765108 ARF5/COPZ1/PLPP3 3 GO:0043090 amino acid import 3/566 52/18722 0.207556653530307 0.45858174765108 ITGB1/SLC43A2/SLC1A5 3 GO:0043392 negative regulation of DNA binding 3/566 52/18722 0.207556653530307 0.45858174765108 TMSB4X/ZNF593/SRI 3 GO:0045103 intermediate filament-based process 3/566 52/18722 0.207556653530307 0.45858174765108 VIM/KRT18/MACF1 3 GO:1903426 regulation of reactive oxygen species biosynthetic process 3/566 52/18722 0.207556653530307 0.45858174765108 CYBA/PARK7/HSPD1 3 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process 4/566 78/18722 0.210197416599661 0.462808555243171 CYCS/HSPD1/HSPE1/PDCD2 4 GO:0008306 associative learning 4/566 78/18722 0.210197416599661 0.462808555243171 LGMN/EIF4A3/ITGB1/APP 4 GO:0032371 regulation of sterol transport 4/566 78/18722 0.210197416599661 0.462808555243171 APOC1/APOE/LRP1/ABCA1 4 GO:0032374 regulation of cholesterol transport 4/566 78/18722 0.210197416599661 0.462808555243171 APOC1/APOE/LRP1/ABCA1 4 GO:0043537 negative regulation of blood vessel endothelial cell migration 4/566 78/18722 0.210197416599661 0.462808555243171 APOE/HMGB1/ATP2B4/PDCD10 4 GO:0061045 negative regulation of wound healing 4/566 78/18722 0.210197416599661 0.462808555243171 APOE/SERPINE2/GJA1/SERPINE1 4 GO:0070373 negative regulation of ERK1 and ERK2 cascade 4/566 78/18722 0.210197416599661 0.462808555243171 GSTP1/TIMP3/FBLN1/SEMA6A 4 GO:0003012 muscle system process 17/566 452/18722 0.210424448353666 0.463079408833673 CALM1/ALDOA/ENO1/ATP2B4/IL6ST/CYBA/DAG1/AKAP9/GSTO1/DSC2/AIF1/GLRX3/GAA/SRI/GJA1/ATP2B1/DSG2 17 GO:0006475 internal protein amino acid acetylation 7/566 160/18722 0.211127183032417 0.464396353191859 MORF4L2/ISL1/PARK7/POLE3/HAT1/RUVBL1/PIH1D1 7 GO:0090287 regulation of cellular response to growth factor stimulus 12/566 304/18722 0.211485659904301 0.464955139700715 FBN2/FBN1/LRP2/CRIM1/HSP90AB1/ATP2B4/FSTL1/ENG/GLG1/FOLR1/HTRA1/SEMA6A 12 GO:0008154 actin polymerization or depolymerization 9/566 217/18722 0.211909756762339 0.465657570141132 PFN1/TMSB10/ARPC2/ARPC5/CFL1/TMSB4X/ARPC1A/AIF1/SCIN 9 GO:0000041 transition metal ion transport 5/566 105/18722 0.212127377157936 0.465676076482807 FTL/B2M/SLC40A1/SLC39A10/TFRC 5 GO:0040029 regulation of gene expression, epigenetic 5/566 105/18722 0.212127377157936 0.465676076482807 XIST/GPX1/POLE3/CDCA4/IGF2 5 GO:0043270 positive regulation of ion transport 11/566 275/18722 0.212276775435509 0.465774373700783 CALM1/SLC6A4/TMSB4X/ITGB1/AKAP9/GSTO1/GLRX/SRI/ATP2B1/PRSS8/P2RY6 11 GO:0031668 cellular response to extracellular stimulus 10/566 246/18722 0.212491887083435 0.466016690293326 HNRNPA1/AOC1/GSTP1/SLC2A1/SLC38A2/GABARAP/AIF1/NUDT15/ATP2B1/FOLR1 10 GO:0062012 regulation of small molecule metabolic process 13/566 334/18722 0.213221535401187 0.46738664480851 CD74/APOC1/APOE/HMGB1/ENO1/ANXA1/ATP2B4/PPP1CA/PARK7/TMSB4X/APP/IGF2/P2RY6 13 GO:0046578 regulation of Ras protein signal transduction 8/566 189/18722 0.214169883790588 0.469234410745914 APOE/STMN1/ADGRG1/MET/NRP1/ITGB1/GABARAP/ABCA1 8 GO:0002707 negative regulation of lymphocyte mediated immunity 3/566 53/18722 0.215457870395341 0.471142218833639 HLA-B/HLA-A/CD46 3 GO:0031279 regulation of cyclase activity 3/566 53/18722 0.215457870395341 0.471142218833639 CALM1/AKAP9/GNAI3 3 GO:0045744 negative regulation of G protein-coupled receptor signaling pathway 3/566 53/18722 0.215457870395341 0.471142218833639 ATP2B4/STMN1/MET 3 GO:0036294 cellular response to decreased oxygen levels 7/566 161/18722 0.215463961712778 0.471142218833639 MALAT1/ENO1/CCNB1/CHCHD2/CCNA2/BNIP3/P4HB 7 GO:0006023 aminoglycan biosynthetic process 4/566 79/18722 0.216560780183843 0.47188055368134 CHPF/HS6ST2/B3GNT3/HEXA 4 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling 4/566 79/18722 0.216560780183843 0.47188055368134 FN1/FLT1/PLXNB1/IGF1R 4 GO:0071887 leukocyte apoptotic process 5/566 106/18722 0.217570545280286 0.47188055368134 RPS6/CD74/ANXA1/TCP1/SLC39A10 5 GO:1905477 positive regulation of protein localization to membrane 5/566 106/18722 0.217570545280286 0.47188055368134 ATP2B4/LRP1/EGFR/ITGB1/PDCD5 5 GO:0009755 hormone-mediated signaling pathway 8/566 190/18722 0.218171983571591 0.47188055368134 DNAJA1/PTGES3/ISL1/LGR5/PARK7/PRLR/PAQR7/CALR 8 GO:0030041 actin filament polymerization 8/566 190/18722 0.218171983571591 0.47188055368134 PFN1/TMSB10/ARPC2/ARPC5/TMSB4X/ARPC1A/AIF1/SCIN 8 GO:0001773 myeloid dendritic cell activation 2/566 29/18722 0.218239456430791 0.47188055368134 HMGB1/ITGB8 2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus 2/566 29/18722 0.218239456430791 0.47188055368134 HLA-DRB1/GPX1 2 GO:0003209 cardiac atrium morphogenesis 2/566 29/18722 0.218239456430791 0.47188055368134 ISL1/ENG 2 GO:0005979 regulation of glycogen biosynthetic process 2/566 29/18722 0.218239456430791 0.47188055368134 PPP1CA/IGF2 2 GO:0010458 exit from mitosis 2/566 29/18722 0.218239456430791 0.47188055368134 RPL24/UBE2S 2 GO:0010962 regulation of glucan biosynthetic process 2/566 29/18722 0.218239456430791 0.47188055368134 PPP1CA/IGF2 2 GO:0019082 viral protein processing 2/566 29/18722 0.218239456430791 0.47188055368134 CANX/MOGS 2 GO:0021602 cranial nerve morphogenesis 2/566 29/18722 0.218239456430791 0.47188055368134 SEMA3F/NRP1 2 GO:0022011 myelination in peripheral nervous system 2/566 29/18722 0.218239456430791 0.47188055368134 DAG1/ITGB4 2 GO:0032292 peripheral nervous system axon ensheathment 2/566 29/18722 0.218239456430791 0.47188055368134 DAG1/ITGB4 2 GO:0033028 myeloid cell apoptotic process 2/566 29/18722 0.218239456430791 0.47188055368134 ANXA1/TCP1 2 GO:0034311 diol metabolic process 2/566 29/18722 0.218239456430791 0.47188055368134 PLPP3/ASAH1 2 GO:0035066 positive regulation of histone acetylation 2/566 29/18722 0.218239456430791 0.47188055368134 ISL1/PIH1D1 2 GO:0062098 regulation of programmed necrotic cell death 2/566 29/18722 0.218239456430791 0.47188055368134 YBX3/ASAH1 2 GO:0071549 cellular response to dexamethasone stimulus 2/566 29/18722 0.218239456430791 0.47188055368134 EGFR/SERPINF1 2 GO:1902547 regulation of cellular response to vascular endothelial growth factor stimulus 2/566 29/18722 0.218239456430791 0.47188055368134 ATP2B4/SEMA6A 2 GO:2000406 positive regulation of T cell migration 2/566 29/18722 0.218239456430791 0.47188055368134 APP/AIF1 2 GO:0051494 negative regulation of cytoskeleton organization 7/566 162/18722 0.219832949430146 0.475095286826705 NPM1/PFN1/STMN1/TMSB10/MET/TMSB4X/SCIN 7 GO:0001508 action potential 6/566 134/18722 0.220002493195278 0.475231004223862 CALM1/AKAP9/DSC2/SRI/GJA1/DSG2 6 GO:0009314 response to radiation 17/566 456/18722 0.220605397103863 0.476302244377497 NPM1/RPL26/ANXA1/CYBA/HMGN1/EGFR/PPP1CA/GPX1/TXN/TRIAP1/CIRBP/ITGB1/RAD51/PBK/APP/LRP5/MME 17 GO:0007422 peripheral nervous system development 4/566 80/18722 0.22297593119317 0.480285711474646 ISL1/CDK1/DAG1/ITGB4 4 GO:1901264 carbohydrate derivative transport 4/566 80/18722 0.22297593119317 0.480285711474646 SLC25A5/PSAP/SLC19A1/GJA1 4 GO:0021761 limbic system development 5/566 107/18722 0.223056706482328 0.480285711474646 ATP2B4/NME1/ARPC5/ANXA3/NRP1 5 GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process 5/566 107/18722 0.223056706482328 0.480285711474646 SUMO2/DDA1/GABARAP/CDC20/UBE2V2 5 GO:0002064 epithelial cell development 9/566 220/18722 0.223089385743126 0.480285711474646 VIM/ADAMTSL4/IL6ST/TYMS/GPX1/RAB25/MET/B4GALT1/IQGAP1 9 GO:0032330 regulation of chondrocyte differentiation 3/566 54/18722 0.22342131816352 0.480285711474646 EFEMP1/SCIN/GLG1 3 GO:0035065 regulation of histone acetylation 3/566 54/18722 0.22342131816352 0.480285711474646 ISL1/PARK7/PIH1D1 3 GO:0072348 sulfur compound transport 3/566 54/18722 0.22342131816352 0.480285711474646 SLC26A2/GJA1/SLC13A4 3 GO:0086002 cardiac muscle cell action potential involved in contraction 3/566 54/18722 0.22342131816352 0.480285711474646 DSC2/GJA1/DSG2 3 GO:0001101 response to acid chemical 6/566 135/18722 0.224870308341119 0.483167284138351 ATP2B4/CYBA/GSTP1/COL4A1/HNRNPD/KRT8 6 GO:0006869 lipid transport 15/566 398/18722 0.226151871259792 0.485686507886443 PLIN2/APOC1/APOE/SPP1/ANXA1/LRP1/PSAP/ATP10D/SLC2A1/TRIAP1/ITGAV/ABCA1/SLC27A2/LRP10/GM2A 15 GO:0006790 sulfur compound metabolic process 13/566 339/18722 0.228240379387055 0.489033033155811 GSTP1/CHPF/SLC26A2/GPX1/SMS/PARK7/HSPA9/GNS/GSTO1/GLRX3/GLB1/B3GNT3/LYRM4 13 GO:0002832 negative regulation of response to biotic stimulus 5/566 108/18722 0.228584165293631 0.489033033155811 HLA-B/HLA-A/RPS19/GRN/HTRA1 5 GO:0034440 lipid oxidation 5/566 108/18722 0.228584165293631 0.489033033155811 ETFB/ACAT2/ECHS1/ECH1/SLC27A2 5 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 4/566 81/18722 0.229440090757378 0.489033033155811 FBN2/FBN1/GLG1/HTRA1 4 GO:2000106 regulation of leukocyte apoptotic process 4/566 81/18722 0.229440090757378 0.489033033155811 CD74/ANXA1/TCP1/SLC39A10 4 GO:0007202 activation of phospholipase C activity 2/566 30/18722 0.229467656393192 0.489033033155811 EGFR/P2RY6 2 GO:0010800 positive regulation of peptidyl-threonine phosphorylation 2/566 30/18722 0.229467656393192 0.489033033155811 CALM1/APP 2 GO:0031571 mitotic G1 DNA damage checkpoint signaling 2/566 30/18722 0.229467656393192 0.489033033155811 RPL26/TRIAP1 2 GO:0034368 protein-lipid complex remodeling 2/566 30/18722 0.229467656393192 0.489033033155811 APOC1/APOE 2 GO:0034369 plasma lipoprotein particle remodeling 2/566 30/18722 0.229467656393192 0.489033033155811 APOC1/APOE 2 GO:0036296 response to increased oxygen levels 2/566 30/18722 0.229467656393192 0.489033033155811 BNIP3/ATP6AP1 2 GO:0044788 modulation by host of viral process 2/566 30/18722 0.229467656393192 0.489033033155811 APOE/CFL1 2 GO:0045070 positive regulation of viral genome replication 2/566 30/18722 0.229467656393192 0.489033033155811 PPIA/PPIH 2 GO:0046825 regulation of protein export from nucleus 2/566 30/18722 0.229467656393192 0.489033033155811 PARK7/TXN 2 GO:0060674 placenta blood vessel development 2/566 30/18722 0.229467656393192 0.489033033155811 SPINT1/ITGB8 2 GO:0070229 negative regulation of lymphocyte apoptotic process 2/566 30/18722 0.229467656393192 0.489033033155811 CD74/SLC39A10 2 GO:0043401 steroid hormone mediated signaling pathway 6/566 136/18722 0.229773045982648 0.489449569719975 DNAJA1/PTGES3/ISL1/PARK7/PAQR7/CALR 6 GO:0010676 positive regulation of cellular carbohydrate metabolic process 3/566 55/18722 0.231441649107789 0.492062188074439 HMGB1/IGF2/P2RY6 3 GO:0042220 response to cocaine 3/566 55/18722 0.231441649107789 0.492062188074439 HSP90AB1/HSPD1/CCNA2 3 GO:0045620 negative regulation of lymphocyte differentiation 3/566 55/18722 0.231441649107789 0.492062188074439 CD74/HMGB1/ANXA1 3 GO:0046164 alcohol catabolic process 3/566 55/18722 0.231441649107789 0.492062188074439 APOE/TPI1/IMPA2 3 GO:0071772 response to BMP 7/566 165/18722 0.233124932198698 0.495168033467844 FBN1/LRP2/CRIM1/FSTL1/SPINT1/ENG/HTRA1 7 GO:0071773 cellular response to BMP stimulus 7/566 165/18722 0.233124932198698 0.495168033467844 FBN1/LRP2/CRIM1/FSTL1/SPINT1/ENG/HTRA1 7 GO:0001892 embryonic placenta development 4/566 82/18722 0.235950490910381 0.500691890149197 KRT19/KRT8/SPINT1/IGF2 4 GO:1905897 regulation of response to endoplasmic reticulum stress 4/566 82/18722 0.235950490910381 0.500691890149197 PARK7/UBXN1/COPS5/TMEM259 4 GO:0023061 signal release 17/566 463/18722 0.238931555821787 0.50677622035188 SPP1/DYNLL1/HLA-DRB1/CALM1/ANXA1/LRP1/EGFR/ISL1/PHPT1/SLC6A4/PARK7/CGA/ABCA1/DPP4/LRP5/SRI/GJA1 17 GO:0010518 positive regulation of phospholipase activity 3/566 56/18722 0.239513611361657 0.506803516056129 FLT1/EGFR/P2RY6 3 GO:0043470 regulation of carbohydrate catabolic process 3/566 56/18722 0.239513611361657 0.506803516056129 HMGB1/PPP1CA/APP 3 GO:0048008 platelet-derived growth factor receptor signaling pathway 3/566 56/18722 0.239513611361657 0.506803516056129 LRP1/NRP1/TXNIP 3 GO:0051058 negative regulation of small GTPase mediated signal transduction 3/566 56/18722 0.239513611361657 0.506803516056129 STMN1/MET/ITGB1 3 GO:0098781 ncRNA transcription 3/566 56/18722 0.239513611361657 0.506803516056129 NCL/NIFK/PIH1D1 3 GO:0002828 regulation of type 2 immune response 2/566 31/18722 0.240732560920949 0.506973207767297 CD74/ANXA1 2 GO:0006301 postreplication repair 2/566 31/18722 0.240732560920949 0.506973207767297 UBE2N/UBE2V2 2 GO:0008045 motor neuron axon guidance 2/566 31/18722 0.240732560920949 0.506973207767297 SEMA3F/NRP1 2 GO:0033238 regulation of cellular amine metabolic process 2/566 31/18722 0.240732560920949 0.506973207767297 ATP2B4/PARK7 2 GO:0044819 mitotic G1/S transition checkpoint signaling 2/566 31/18722 0.240732560920949 0.506973207767297 RPL26/TRIAP1 2 GO:0048710 regulation of astrocyte differentiation 2/566 31/18722 0.240732560920949 0.506973207767297 IL6ST/SERPINE2 2 GO:0060045 positive regulation of cardiac muscle cell proliferation 2/566 31/18722 0.240732560920949 0.506973207767297 CCNB1/CDK1 2 GO:0070633 transepithelial transport 2/566 31/18722 0.240732560920949 0.506973207767297 ACTG1/P2RY6 2 GO:0070723 response to cholesterol 2/566 31/18722 0.240732560920949 0.506973207767297 DAG1/ABCA1 2 GO:2000144 positive regulation of DNA-templated transcription, initiation 2/566 31/18722 0.240732560920949 0.506973207767297 SUB1/MED4 2 GO:0007254 JNK cascade 7/566 167/18722 0.242132075692567 0.509438563791733 HMGB1/DNAJA1/GSTP1/EGFR/APP/IGF1R/COPS5 7 GO:0034728 nucleosome organization 7/566 167/18722 0.242132075692567 0.509438563791733 NPM1/HMGB2/DNAJC9/POLE3/ITGB3BP/HAT1/SUPT16H 7 GO:0043367 CD4-positive, alpha-beta T cell differentiation 4/566 83/18722 0.242504377438068 0.509499522583427 HMGB1/HLA-DRB1/ANXA1/HLA-DRA 4 GO:0050672 negative regulation of lymphocyte proliferation 4/566 83/18722 0.242504377438068 0.509499522583427 HLA-DRB1/TYROBP/GPNMB/MNDA 4 GO:0050886 endocrine process 4/566 83/18722 0.242504377438068 0.509499522583427 CYBA/CGA/GJA1/MME 4 GO:0006006 glucose metabolic process 8/566 196/18722 0.242749951878986 0.509774898945872 GAPDH/HMGB1/TPI1/ENO1/PPP1CA/IGF2/LRP5/GAA 8 GO:0051924 regulation of calcium ion transport 10/566 255/18722 0.244527528496802 0.513265703379426 CALM1/VDAC1/C4orf3/CYBA/AHNAK/GSTO1/SRI/GJA1/ATP2B1/P2RY6 10 GO:0016579 protein deubiquitination 6/566 139/18722 0.244679225325025 0.513342088193691 CDK1/PARK7/UBXN1/PSMD14/UCHL3/COPS5 6 GO:0001938 positive regulation of endothelial cell proliferation 5/566 111/18722 0.245397310455154 0.514606135726023 HMGB2/HMGB1/CYBA/NRP1/IGF2 5 GO:0010257 NADH dehydrogenase complex assembly 3/566 57/18722 0.24763205312166 0.517585868778229 NDUFB3/NDUFA10/NDUFS3 3 GO:0010883 regulation of lipid storage 3/566 57/18722 0.24763205312166 0.517585868778229 PLIN2/ITGAV/ABCA1 3 GO:0032981 mitochondrial respiratory chain complex I assembly 3/566 57/18722 0.24763205312166 0.517585868778229 NDUFB3/NDUFA10/NDUFS3 3 GO:0033619 membrane protein proteolysis 3/566 57/18722 0.24763205312166 0.517585868778229 APOE/DAG1/TIMP3 3 GO:0051289 protein homotetramerization 3/566 57/18722 0.24763205312166 0.517585868778229 ALDOA/B2M/TK1 3 GO:0051785 positive regulation of nuclear division 3/566 57/18722 0.24763205312166 0.517585868778229 ANAPC11/IGF2/LRP5 3 GO:0097120 receptor localization to synapse 3/566 57/18722 0.24763205312166 0.517585868778229 TYROBP/DAG1/CLSTN1 3 GO:0034976 response to endoplasmic reticulum stress 10/566 256/18722 0.248190527823937 0.517621221524797 PARK7/AMFR/UBXN1/HSP90B1/CANX/EDEM3/P4HB/COPS5/TMEM259/CALR 10 GO:0006970 response to osmotic stress 4/566 84/18722 0.249099012585584 0.517621221524797 HSP90AB1/YBX3/EGFR/SLC2A1 4 GO:0010921 regulation of phosphatase activity 4/566 84/18722 0.249099012585584 0.517621221524797 CALM1/HSP90AB1/HSP90B1/SLC39A10 4 GO:0032945 negative regulation of mononuclear cell proliferation 4/566 84/18722 0.249099012585584 0.517621221524797 HLA-DRB1/TYROBP/GPNMB/MNDA 4 GO:0042310 vasoconstriction 4/566 84/18722 0.249099012585584 0.517621221524797 EGFR/SLC6A4/GJA1/ATP2B1 4 GO:0097061 dendritic spine organization 4/566 84/18722 0.249099012585584 0.517621221524797 APOE/LGMN/CFL1/IGF1R 4 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 4/566 84/18722 0.249099012585584 0.517621221524797 RPL26/TRIAP1/CDK2AP2/GPNMB 4 GO:0050768 negative regulation of neurogenesis 6/566 140/18722 0.249710056334751 0.517621221524797 SPP1/B2M/SEMA6D/SEMA3F/NRP1/SEMA6A 6 GO:0002526 acute inflammatory response 5/566 112/18722 0.251072932810481 0.517621221524797 FN1/IL6ST/GSTP1/PARK7/B4GALT1 5 GO:0010633 negative regulation of epithelial cell migration 5/566 112/18722 0.251072932810481 0.517621221524797 APOE/HMGB1/ATP2B4/PDCD10/SERPINF1 5 GO:0043406 positive regulation of MAP kinase activity 5/566 112/18722 0.251072932810481 0.517621221524797 RPS3/FLT1/EGFR/PDCD10/IQGAP1 5 GO:0000075 cell cycle checkpoint signaling 7/566 169/18722 0.25124795615483 0.517621221524797 RPL26/MAD2L1/CCNB1/CDK1/BUB3/TRIAP1/ZWINT 7 GO:0018394 peptidyl-lysine acetylation 7/566 169/18722 0.25124795615483 0.517621221524797 MORF4L2/ISL1/PARK7/POLE3/HAT1/RUVBL1/PIH1D1 7 GO:0030217 T cell differentiation 10/566 257/18722 0.251872687397422 0.517621221524797 RPS6/CD74/HMGB1/HLA-DRB1/FCER1G/ANXA1/HLA-DRA/B2M/CD46/CLPTM1 10 GO:0010039 response to iron ion 2/566 32/18722 0.252021713731775 0.517621221524797 CCNB1/B2M 2 GO:0010743 regulation of macrophage derived foam cell differentiation 2/566 32/18722 0.252021713731775 0.517621221524797 ITGAV/ABCA1 2 GO:0014044 Schwann cell development 2/566 32/18722 0.252021713731775 0.517621221524797 DAG1/ITGB4 2 GO:0021799 cerebral cortex radially oriented cell migration 2/566 32/18722 0.252021713731775 0.517621221524797 ADGRG1/LAMB1 2 GO:0034243 regulation of transcription elongation from RNA polymerase II promoter 2/566 32/18722 0.252021713731775 0.517621221524797 SUPT16H/GTF2F1 2 GO:0034367 protein-containing complex remodeling 2/566 32/18722 0.252021713731775 0.517621221524797 APOC1/APOE 2 GO:0035456 response to interferon-beta 2/566 32/18722 0.252021713731775 0.517621221524797 IFITM2/MNDA 2 GO:0042219 cellular modified amino acid catabolic process 2/566 32/18722 0.252021713731775 0.517621221524797 MTHFS/PCYOX1 2 GO:0045684 positive regulation of epidermis development 2/566 32/18722 0.252021713731775 0.517621221524797 KRT10/NME2 2 GO:0045761 regulation of adenylate cyclase activity 2/566 32/18722 0.252021713731775 0.517621221524797 AKAP9/GNAI3 2 GO:0051642 centrosome localization 2/566 32/18722 0.252021713731775 0.517621221524797 MAD2L1/AKAP9 2 GO:0071875 adrenergic receptor signaling pathway 2/566 32/18722 0.252021713731775 0.517621221524797 ATP2B4/ADRB1 2 GO:0090022 regulation of neutrophil chemotaxis 2/566 32/18722 0.252021713731775 0.517621221524797 CD74/DPP4 2 GO:1901185 negative regulation of ERBB signaling pathway 2/566 32/18722 0.252021713731775 0.517621221524797 EGFR/LGMN 2 GO:1901532 regulation of hematopoietic progenitor cell differentiation 2/566 32/18722 0.252021713731775 0.517621221524797 HSPA9/PDCD2 2 GO:1903955 positive regulation of protein targeting to mitochondrion 2/566 32/18722 0.252021713731775 0.517621221524797 UBE2L3/PDCD5 2 GO:2000515 negative regulation of CD4-positive, alpha-beta T cell activation 2/566 32/18722 0.252021713731775 0.517621221524797 HMGB1/ANXA1 2 GO:0008584 male gonad development 6/566 141/18722 0.25476998653563 0.517621221524797 LRP2/HMGB2/YBX3/ADGRG1/EIF2S2/MEA1 6 GO:0048284 organelle fusion 6/566 141/18722 0.25476998653563 0.517621221524797 ANXA1/CDK1/STOML2/BNIP3/GNAI3/TFRC 6 GO:0045069 regulation of viral genome replication 4/566 85/18722 0.255731677626623 0.517621221524797 PPIA/BANF1/IFITM2/PPIH 4 GO:0007131 reciprocal meiotic recombination 3/566 58/18722 0.255791926356597 0.517621221524797 RAD51/MND1/CCNB1IP1 3 GO:0009161 ribonucleoside monophosphate metabolic process 3/566 58/18722 0.255791926356597 0.517621221524797 IMPDH2/UMPS/GMPS 3 GO:0010574 regulation of vascular endothelial growth factor production 3/566 58/18722 0.255791926356597 0.517621221524797 NUTF2/IL6ST/ISL1 3 GO:0032387 negative regulation of intracellular transport 3/566 58/18722 0.255791926356597 0.517621221524797 PARK7/TXN/LMAN1 3 GO:0043506 regulation of JUN kinase activity 3/566 58/18722 0.255791926356597 0.517621221524797 RPS3/DNAJA1/GSTP1 3 GO:0097035 regulation of membrane lipid distribution 3/566 58/18722 0.255791926356597 0.517621221524797 ATP10D/TRIAP1/ABCA1 3 GO:0140527 reciprocal homologous recombination 3/566 58/18722 0.255791926356597 0.517621221524797 RAD51/MND1/CCNB1IP1 3 GO:1902808 positive regulation of cell cycle G1/S phase transition 3/566 58/18722 0.255791926356597 0.517621221524797 ANXA1/EGFR/AIF1 3 GO:0050804 modulation of chemical synaptic transmission 16/566 439/18722 0.256506743450693 0.517621221524797 APOE/CALM1/TYROBP/CDH1/SERPINE2/SRGN/EGFR/LGMN/SLC6A4/EIF4A3/ITGB1/AKAP9/CDC20/CLSTN1/APP/MME 16 GO:0044106 cellular amine metabolic process 5/566 113/18722 0.256781334547812 0.517621221524797 AOC1/ATP2B4/OAZ1/SMS/PARK7 5 GO:0099177 regulation of trans-synaptic signaling 16/566 440/18722 0.259346621707494 0.517621221524797 APOE/CALM1/TYROBP/CDH1/SERPINE2/SRGN/EGFR/LGMN/SLC6A4/EIF4A3/ITGB1/AKAP9/CDC20/CLSTN1/APP/MME 16 GO:0046546 development of primary male sexual characteristics 6/566 142/18722 0.259857839284942 0.517621221524797 LRP2/HMGB2/YBX3/ADGRG1/EIF2S2/MEA1 6 GO:0097553 calcium ion transmembrane import into cytosol 6/566 142/18722 0.259857839284942 0.517621221524797 CALM1/ATP2B4/CYBA/GSTO1/SRI/P2RY6 6 GO:0030833 regulation of actin filament polymerization 7/566 171/18722 0.260465692255013 0.517621221524797 PFN1/TMSB10/ARPC2/ARPC5/TMSB4X/ARPC1A/SCIN 7 GO:0046890 regulation of lipid biosynthetic process 7/566 171/18722 0.260465692255013 0.517621221524797 CD74/APOC1/APOE/ANXA1/CGA/ASAH1/RAB38 7 GO:0032413 negative regulation of ion transmembrane transporter activity 4/566 86/18722 0.262399675297416 0.517621221524797 CALM1/C4orf3/GSTO1/SRI 4 GO:0019751 polyol metabolic process 5/566 114/18722 0.262520814213985 0.517621221524797 TPI1/IMPA2/PLPP3/ASAH1/P2RY6 5 GO:0009416 response to light stimulus 12/566 320/18722 0.26328313290003 0.517621221524797 NPM1/RPL26/HMGN1/EGFR/PPP1CA/GPX1/TRIAP1/CIRBP/ITGB1/PBK/APP/MME 12 GO:0003382 epithelial cell morphogenesis 2/566 33/18722 0.26332337562302 0.517621221524797 RAB25/MET 2 GO:0006336 DNA replication-independent nucleosome assembly 2/566 33/18722 0.26332337562302 0.517621221524797 ITGB3BP/HAT1 2 GO:0010165 response to X-ray 2/566 33/18722 0.26332337562302 0.517621221524797 ANXA1/RAD51 2 GO:0032633 interleukin-4 production 2/566 33/18722 0.26332337562302 0.517621221524797 HLA-DRB1/FCER1G 2 GO:0032673 regulation of interleukin-4 production 2/566 33/18722 0.26332337562302 0.517621221524797 HLA-DRB1/FCER1G 2 GO:0033198 response to ATP 2/566 33/18722 0.26332337562302 0.517621221524797 HSPD1/HSP90B1 2 GO:0036336 dendritic cell migration 2/566 33/18722 0.26332337562302 0.517621221524797 HMGB1/CALR 2 GO:0040020 regulation of meiotic nuclear division 2/566 33/18722 0.26332337562302 0.517621221524797 CDC20/CALR 2 GO:0071295 cellular response to vitamin 2/566 33/18722 0.26332337562302 0.517621221524797 ATP2B1/FOLR1 2 GO:1901976 regulation of cell cycle checkpoint 2/566 33/18722 0.26332337562302 0.517621221524797 MAD2L1/CCNB1 2 GO:0006473 protein acetylation 8/566 201/18722 0.263901045076378 0.517621221524797 MORF4L2/ISL1/PARK7/POLE3/HAT1/NAA20/RUVBL1/PIH1D1 8 GO:0043407 negative regulation of MAP kinase activity 3/566 59/18722 0.263988290053979 0.517621221524797 APOE/DNAJA1/GSTP1 3 GO:2001258 negative regulation of cation channel activity 3/566 59/18722 0.263988290053979 0.517621221524797 CALM1/GSTO1/SRI 3 GO:0000255 allantoin metabolic process 1/566 10/18722 0.264391432557814 0.517621221524797 DNPH1 1 GO:0000338 protein deneddylation 1/566 10/18722 0.264391432557814 0.517621221524797 COPS5 1 GO:0001820 serotonin secretion 1/566 10/18722 0.264391432557814 0.517621221524797 SLC6A4 1 GO:0002002 regulation of angiotensin levels in blood 1/566 10/18722 0.264391432557814 0.517621221524797 MME 1 GO:0002003 angiotensin maturation 1/566 10/18722 0.264391432557814 0.517621221524797 MME 1 GO:0002934 desmosome organization 1/566 10/18722 0.264391432557814 0.517621221524797 DSG2 1 GO:0003056 regulation of vascular associated smooth muscle contraction 1/566 10/18722 0.264391432557814 0.517621221524797 ATP2B1 1 GO:0003163 sinoatrial node development 1/566 10/18722 0.264391432557814 0.517621221524797 ISL1 1 GO:0006222 UMP biosynthetic process 1/566 10/18722 0.264391432557814 0.517621221524797 UMPS 1 GO:0006283 transcription-coupled nucleotide-excision repair 1/566 10/18722 0.264391432557814 0.517621221524797 HMGN1 1 GO:0006735 NADH regeneration 1/566 10/18722 0.264391432557814 0.517621221524797 ENO1 1 GO:0009113 purine nucleobase biosynthetic process 1/566 10/18722 0.264391432557814 0.517621221524797 GMPS 1 GO:0009170 purine deoxyribonucleoside monophosphate metabolic process 1/566 10/18722 0.264391432557814 0.517621221524797 DNPH1 1 GO:0009174 pyrimidine ribonucleoside monophosphate biosynthetic process 1/566 10/18722 0.264391432557814 0.517621221524797 UMPS 1 GO:0009396 folic acid-containing compound biosynthetic process 1/566 10/18722 0.264391432557814 0.517621221524797 MTHFS 1 GO:0009750 response to fructose 1/566 10/18722 0.264391432557814 0.517621221524797 KRT18 1 GO:0010172 embryonic body morphogenesis 1/566 10/18722 0.264391432557814 0.517621221524797 DAG1 1 GO:0010992 ubiquitin recycling 1/566 10/18722 0.264391432557814 0.517621221524797 UBE2S 1 GO:0010998 regulation of translational initiation by eIF2 alpha phosphorylation 1/566 10/18722 0.264391432557814 0.517621221524797 NPM1 1 GO:0015911 long-chain fatty acid import across plasma membrane 1/566 10/18722 0.264391432557814 0.517621221524797 SLC2A1 1 GO:0017085 response to insecticide 1/566 10/18722 0.264391432557814 0.517621221524797 CCNB1 1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline 1/566 10/18722 0.264391432557814 0.517621221524797 P4HB 1 GO:0019062 virion attachment to host cell 1/566 10/18722 0.264391432557814 0.517621221524797 HSP90AB1 1 GO:0019532 oxalate transport 1/566 10/18722 0.264391432557814 0.517621221524797 SLC26A2 1 GO:0021562 vestibulocochlear nerve development 1/566 10/18722 0.264391432557814 0.517621221524797 NRP1 1 GO:0021932 hindbrain radial glia guided cell migration 1/566 10/18722 0.264391432557814 0.517621221524797 ITGB1 1 GO:0030388 fructose 1,6-bisphosphate metabolic process 1/566 10/18722 0.264391432557814 0.517621221524797 ALDOA 1 GO:0031055 chromatin remodeling at centromere 1/566 10/18722 0.264391432557814 0.517621221524797 ITGB3BP 1 GO:0031118 rRNA pseudouridine synthesis 1/566 10/18722 0.264391432557814 0.517621221524797 NHP2 1 GO:0031125 rRNA 3'-end processing 1/566 10/18722 0.264391432557814 0.517621221524797 EXOSC9 1 GO:0031340 positive regulation of vesicle fusion 1/566 10/18722 0.264391432557814 0.517621221524797 ANXA1 1 GO:0031915 positive regulation of synaptic plasticity 1/566 10/18722 0.264391432557814 0.517621221524797 CDC20 1 GO:0032275 luteinizing hormone secretion 1/566 10/18722 0.264391432557814 0.517621221524797 CGA 1 GO:0033572 transferrin transport 1/566 10/18722 0.264391432557814 0.517621221524797 TFRC 1 GO:0034756 regulation of iron ion transport 1/566 10/18722 0.264391432557814 0.517621221524797 B2M 1 GO:0035376 sterol import 1/566 10/18722 0.264391432557814 0.517621221524797 LRP1 1 GO:0035646 endosome to melanosome transport 1/566 10/18722 0.264391432557814 0.517621221524797 RAB38 1 GO:0035907 dorsal aorta development 1/566 10/18722 0.264391432557814 0.517621221524797 ENG 1 GO:0043485 endosome to pigment granule transport 1/566 10/18722 0.264391432557814 0.517621221524797 RAB38 1 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence 1/566 10/18722 0.264391432557814 0.517621221524797 EMC1 1 GO:0045625 regulation of T-helper 1 cell differentiation 1/566 10/18722 0.264391432557814 0.517621221524797 ANXA1 1 GO:0045843 negative regulation of striated muscle tissue development 1/566 10/18722 0.264391432557814 0.517621221524797 YBX3 1 GO:0045898 regulation of RNA polymerase II transcription preinitiation complex assembly 1/566 10/18722 0.264391432557814 0.517621221524797 HMGB1 1 GO:0048671 negative regulation of collateral sprouting 1/566 10/18722 0.264391432557814 0.517621221524797 SPP1 1 GO:0048672 positive regulation of collateral sprouting 1/566 10/18722 0.264391432557814 0.517621221524797 LRP1 1 GO:0048757 pigment granule maturation 1/566 10/18722 0.264391432557814 0.517621221524797 RAB38 1 GO:0050861 positive regulation of B cell receptor signaling pathway 1/566 10/18722 0.264391432557814 0.517621221524797 SLC39A10 1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity 1/566 10/18722 0.264391432557814 0.517621221524797 CALM1 1 GO:0051351 positive regulation of ligase activity 1/566 10/18722 0.264391432557814 0.517621221524797 TMSB4X 1 GO:0051660 establishment of centrosome localization 1/566 10/18722 0.264391432557814 0.517621221524797 MAD2L1 1 GO:0051918 negative regulation of fibrinolysis 1/566 10/18722 0.264391432557814 0.517621221524797 SERPINE1 1 GO:0060068 vagina development 1/566 10/18722 0.264391432557814 0.517621221524797 LRP2 1 GO:0060736 prostate gland growth 1/566 10/18722 0.264391432557814 0.517621221524797 PSAP 1 GO:0060768 regulation of epithelial cell proliferation involved in prostate gland development 1/566 10/18722 0.264391432557814 0.517621221524797 SERPINF1 1 GO:0061621 canonical glycolysis 1/566 10/18722 0.264391432557814 0.517621221524797 ENO1 1 GO:0061718 glucose catabolic process to pyruvate 1/566 10/18722 0.264391432557814 0.517621221524797 ENO1 1 GO:0070508 cholesterol import 1/566 10/18722 0.264391432557814 0.517621221524797 LRP1 1 GO:0071073 positive regulation of phospholipid biosynthetic process 1/566 10/18722 0.264391432557814 0.517621221524797 RAB38 1 GO:0090043 regulation of tubulin deacetylation 1/566 10/18722 0.264391432557814 0.517621221524797 BEX4 1 GO:0090209 negative regulation of triglyceride metabolic process 1/566 10/18722 0.264391432557814 0.517621221524797 APOE 1 GO:0097084 vascular associated smooth muscle cell development 1/566 10/18722 0.264391432557814 0.517621221524797 ENG 1 GO:0097278 complement-dependent cytotoxicity 1/566 10/18722 0.264391432557814 0.517621221524797 HSP90AB1 1 GO:0098885 modification of postsynaptic actin cytoskeleton 1/566 10/18722 0.264391432557814 0.517621221524797 PFN1 1 GO:0098917 retrograde trans-synaptic signaling 1/566 10/18722 0.264391432557814 0.517621221524797 DAG1 1 GO:0140059 dendrite arborization 1/566 10/18722 0.264391432557814 0.517621221524797 NRP1 1 GO:1901203 positive regulation of extracellular matrix assembly 1/566 10/18722 0.264391432557814 0.517621221524797 DAG1 1 GO:1901978 positive regulation of cell cycle checkpoint 1/566 10/18722 0.264391432557814 0.517621221524797 MAD2L1 1 GO:1902946 protein localization to early endosome 1/566 10/18722 0.264391432557814 0.517621221524797 NRP1 1 GO:1903867 extraembryonic membrane development 1/566 10/18722 0.264391432557814 0.517621221524797 HTRA1 1 GO:1904896 ESCRT complex disassembly 1/566 10/18722 0.264391432557814 0.517621221524797 CHMP5 1 GO:1904903 ESCRT III complex disassembly 1/566 10/18722 0.264391432557814 0.517621221524797 CHMP5 1 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus 1/566 10/18722 0.264391432557814 0.517621221524797 EIF4A3 1 GO:1990535 neuron projection maintenance 1/566 10/18722 0.264391432557814 0.517621221524797 APP 1 GO:2000234 positive regulation of rRNA processing 1/566 10/18722 0.264391432557814 0.517621221524797 TRMT112 1 GO:2000288 positive regulation of myoblast proliferation 1/566 10/18722 0.264391432557814 0.517621221524797 MALAT1 1 GO:2000425 regulation of apoptotic cell clearance 1/566 10/18722 0.264391432557814 0.517621221524797 HMGB1 1 GO:2000510 positive regulation of dendritic cell chemotaxis 1/566 10/18722 0.264391432557814 0.517621221524797 CALR 1 GO:2001223 negative regulation of neuron migration 1/566 10/18722 0.264391432557814 0.517621221524797 ADGRG1 1 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 1/566 10/18722 0.264391432557814 0.517621221524797 PPP1CA 1 GO:0006865 amino acid transport 6/566 143/18722 0.264972435911505 0.518302849155545 SLC38A2/ITGB1/SLC38A10/SLC43A2/GJA1/SLC1A5 6 GO:0031023 microtubule organizing center organization 6/566 143/18722 0.264972435911505 0.518302849155545 NPM1/RANBP1/CDK1/HAUS1/CHMP5/HAUS8 6 GO:0042770 signal transduction in response to DNA damage 7/566 172/18722 0.265110587995557 0.518345339374713 NPM1/CD74/RPL26/MIF/EEF1E1/CDK1/TRIAP1 7 GO:0002429 immune response-activating cell surface receptor signaling pathway 11/566 291/18722 0.266988265189168 0.521101164674343 RPS3/HLA-DRB1/TYROBP/FCER1G/HLA-A/HLA-DPB1/UBE2N/PHPT1/STOML2/SLC39A10/MNDA 11 GO:0002757 immune response-activating signal transduction 11/566 291/18722 0.266988265189168 0.521101164674343 RPS3/HLA-DRB1/TYROBP/FCER1G/HLA-A/HLA-DPB1/UBE2N/PHPT1/STOML2/SLC39A10/MNDA 11 GO:0016236 macroautophagy 11/566 291/18722 0.266988265189168 0.521101164674343 GAPDH/CALM1/VDAC1/QSOX1/SLC25A5/GABARAP/BNIP3/VPS13C/GNAI3/TMEM41B/SMG1 11 GO:0060485 mesenchyme development 11/566 291/18722 0.266988265189168 0.521101164674343 FN1/LAMA5/HNRNPAB/ISL1/SEMA6D/SEMA3F/NRP1/ENG/DAG1/FOLR1/SEMA6A 11 GO:0051209 release of sequestered calcium ion into cytosol 5/566 115/18722 0.268289674336239 0.523411757294013 CALM1/CYBA/GSTO1/SRI/P2RY6 5 GO:1903578 regulation of ATP metabolic process 4/566 87/18722 0.269100332098195 0.524533572023277 ENO1/TMSB4X/COX7A2L/APP 4 GO:2000177 regulation of neural precursor cell proliferation 4/566 87/18722 0.269100332098195 0.524533572023277 LRP2/SLC6A4/ADGRG1/SPINT1 4 GO:0010469 regulation of signaling receptor activity 7/566 173/18722 0.269778339404683 0.52562501839372 PARK7/CGA/NRP1/ITGB1/AKAP9/APP/SERPINE1 7 GO:0014065 phosphatidylinositol 3-kinase signaling 6/566 144/18722 0.270112596524433 0.526046054123698 FN1/FLT1/SERPINE2/EGFR/PLXNB1/IGF1R 6 GO:0000381 regulation of alternative mRNA splicing, via spliceosome 3/566 60/18722 0.272216313032586 0.528524651382936 HNRNPA1/MAGOH/RBM8A 3 GO:0006081 cellular aldehyde metabolic process 3/566 60/18722 0.272216313032586 0.528524651382936 TPI1/PARK7/ESD 3 GO:0006289 nucleotide-excision repair 3/566 60/18722 0.272216313032586 0.528524651382936 HMGB1/HMGN1/RPA3 3 GO:0035825 homologous recombination 3/566 60/18722 0.272216313032586 0.528524651382936 RAD51/MND1/CCNB1IP1 3 GO:0055008 cardiac muscle tissue morphogenesis 3/566 60/18722 0.272216313032586 0.528524651382936 LRP2/ISL1/ENG 3 GO:0060038 cardiac muscle cell proliferation 3/566 60/18722 0.272216313032586 0.528524651382936 CCNB1/CDK1/GJA1 3 GO:1903670 regulation of sprouting angiogenesis 3/566 60/18722 0.272216313032586 0.528524651382936 HMGB1/PKM/SEMA6A 3 GO:0006643 membrane lipid metabolic process 8/566 203/18722 0.272511815778821 0.528637300151334 PSAP/ITGB8/PLPP3/HEXB/ASAH1/GLB1/HEXA/GM2A 8 GO:0060541 respiratory system development 8/566 203/18722 0.272511815778821 0.528637300151334 LAMA5/HMGB1/EGFR/PTGES3/SPARC/PPP1CA/DAG1/MME 8 GO:0030518 intracellular steroid hormone receptor signaling pathway 5/566 116/18722 0.274086222725765 0.529075712969199 DNAJA1/PTGES3/ISL1/PARK7/CALR 5 GO:0051283 negative regulation of sequestering of calcium ion 5/566 116/18722 0.274086222725765 0.529075712969199 CALM1/CYBA/GSTO1/SRI/P2RY6 5 GO:0045619 regulation of lymphocyte differentiation 7/566 174/18722 0.274468071271398 0.529075712969199 CD74/HMGB1/HLA-DRB1/ANXA1/HLA-DRA/CD46/CLPTM1 7 GO:0006356 regulation of transcription by RNA polymerase I 2/566 34/18722 0.274626492628179 0.529075712969199 NCL/PIH1D1 2 GO:0010614 negative regulation of cardiac muscle hypertrophy 2/566 34/18722 0.274626492628179 0.529075712969199 ATP2B4/GLRX3 2 GO:0016242 negative regulation of macroautophagy 2/566 34/18722 0.274626492628179 0.529075712969199 QSOX1/SMG1 2 GO:0035909 aorta morphogenesis 2/566 34/18722 0.274626492628179 0.529075712969199 LRP1/ENG 2 GO:0048261 negative regulation of receptor-mediated endocytosis 2/566 34/18722 0.274626492628179 0.529075712969199 APOC1/ITGAV 2 GO:0050869 negative regulation of B cell activation 2/566 34/18722 0.274626492628179 0.529075712969199 TYROBP/MNDA 2 GO:2000758 positive regulation of peptidyl-lysine acetylation 2/566 34/18722 0.274626492628179 0.529075712969199 ISL1/PIH1D1 2 GO:0051961 negative regulation of nervous system development 6/566 145/18722 0.275277140804399 0.529075712969199 SPP1/B2M/SEMA6D/SEMA3F/NRP1/SEMA6A 6 GO:0061351 neural precursor cell proliferation 6/566 145/18722 0.275277140804399 0.529075712969199 LRP2/SLC6A4/ADGRG1/PSMG1/SPINT1/PLXNB2 6 GO:0050829 defense response to Gram-negative bacterium 4/566 88/18722 0.275831000465044 0.529075712969199 LYZ/HMGB2/RPS19/SERPINE1 4 GO:1901657 glycosyl compound metabolic process 4/566 88/18722 0.275831000465044 0.529075712969199 ERH/TK1/UMPS/DNPH1 4 GO:0008544 epidermis development 12/566 324/18722 0.276875598565065 0.529075712969199 YBX1/LAMA5/HLA-DRB1/ANXA1/EGFR/SVEP1/LGR5/KRT10/STS/NME2/ASAH1/TXNIP 12 GO:0045786 negative regulation of cell cycle 14/566 385/18722 0.277371588761931 0.529075712969199 NPM1/RPL26/MAD2L1/CCNB1/EGFR/CDK1/HPGD/BUB3/TRIAP1/PTTG1/GMNN/CDK2AP2/ZWINT/GPNMB 14 GO:0010948 negative regulation of cell cycle process 11/566 294/18722 0.277736966879816 0.529075712969199 NPM1/RPL26/MAD2L1/CCNB1/CDK1/BUB3/TRIAP1/PTTG1/CDK2AP2/ZWINT/GPNMB 11 GO:0048771 tissue remodeling 7/566 175/18722 0.279178906498067 0.529075712969199 SPP1/EGFR/GPNMB/LRP5/GJA1/ATP6AP1/TFRC 7 GO:0050954 sensory perception of mechanical stimulus 7/566 175/18722 0.279178906498067 0.529075712969199 LRP2/SERPINE2/BIRC5/GPX1/RPL38/HEXB/TIMM9 7 GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway 6/566 146/18722 0.28046488877707 0.529075712969199 ATP2B4/LGR5/ADGRG1/ABCA1/NME2/ADRB1 6 GO:0006900 vesicle budding from membrane 3/566 61/18722 0.280471276348588 0.529075712969199 S100A10/CHMP5/TFG 3 GO:0001818 negative regulation of cytokine production 13/566 357/18722 0.285544093630775 0.529075712969199 FN1/HMGB1/HLA-DRB1/HSP90AB1/TYROBP/ANXA1/NUTF2/GSTP1/SERPINB1/SRGN/TMSB4X/GPNMB/ATP2B1 13 GO:0016331 morphogenesis of embryonic epithelium 6/566 147/18722 0.28567466156841 0.529075712969199 PFN1/LRP2/LAMA5/SPINT1/PLXNB2/FOLR1 6 GO:0009308 amine metabolic process 5/566 118/18722 0.285755649479472 0.529075712969199 AOC1/ATP2B4/OAZ1/SMS/PARK7 5 GO:0022612 gland morphogenesis 5/566 118/18722 0.285755649479472 0.529075712969199 LAMA5/PLXNA1/NRP1/DAG1/LRP5 5 GO:0051282 regulation of sequestering of calcium ion 5/566 118/18722 0.285755649479472 0.529075712969199 CALM1/CYBA/GSTO1/SRI/P2RY6 5 GO:0007020 microtubule nucleation 2/566 35/18722 0.285920665437907 0.529075712969199 AKAP9/TUBGCP2 2 GO:0008608 attachment of spindle microtubules to kinetochore 2/566 35/18722 0.285920665437907 0.529075712969199 CCNB1/BUB3 2 GO:0010765 positive regulation of sodium ion transport 2/566 35/18722 0.285920665437907 0.529075712969199 GLRX/PRSS8 2 GO:0019068 virion assembly 2/566 35/18722 0.285920665437907 0.529075712969199 APOE/CHMP5 2 GO:0032205 negative regulation of telomere maintenance 2/566 35/18722 0.285920665437907 0.529075712969199 HNRNPA1/HNRNPC 2 GO:0033280 response to vitamin D 2/566 35/18722 0.285920665437907 0.529075712969199 SPP1/ATP2B1 2 GO:0034405 response to fluid shear stress 2/566 35/18722 0.285920665437907 0.529075712969199 ABCA1/GJA1 2 GO:0042462 eye photoreceptor cell development 2/566 35/18722 0.285920665437907 0.529075712969199 TUG1/NAGLU 2 GO:0043243 positive regulation of protein-containing complex disassembly 2/566 35/18722 0.285920665437907 0.529075712969199 BNIP3/IGF1R 2 GO:0044273 sulfur compound catabolic process 2/566 35/18722 0.285920665437907 0.529075712969199 GNS/GLB1 2 GO:0045907 positive regulation of vasoconstriction 2/566 35/18722 0.285920665437907 0.529075712969199 EGFR/GJA1 2 GO:0071108 protein K48-linked deubiquitination 2/566 35/18722 0.285920665437907 0.529075712969199 PARK7/UBXN1 2 GO:0086005 ventricular cardiac muscle cell action potential 2/566 35/18722 0.285920665437907 0.529075712969199 DSC2/DSG2 2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis 2/566 35/18722 0.285920665437907 0.529075712969199 ANXA1/NRP1 2 GO:0098801 regulation of renal system process 2/566 35/18722 0.285920665437907 0.529075712969199 CYBA/GJA1 2 GO:2000403 positive regulation of lymphocyte migration 2/566 35/18722 0.285920665437907 0.529075712969199 APP/AIF1 2 GO:0001765 membrane raft assembly 1/566 11/18722 0.286642097862019 0.529075712969199 S100A10 1 GO:0001967 suckling behavior 1/566 11/18722 0.286642097862019 0.529075712969199 APP 1 GO:0002604 regulation of dendritic cell antigen processing and presentation 1/566 11/18722 0.286642097862019 0.529075712969199 CD74 1 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin 1/566 11/18722 0.286642097862019 0.529075712969199 CD46 1 GO:0003263 cardioblast proliferation 1/566 11/18722 0.286642097862019 0.529075712969199 ISL1 1 GO:0003264 regulation of cardioblast proliferation 1/566 11/18722 0.286642097862019 0.529075712969199 ISL1 1 GO:0006020 inositol metabolic process 1/566 11/18722 0.286642097862019 0.529075712969199 IMPA2 1 GO:0006527 arginine catabolic process 1/566 11/18722 0.286642097862019 0.529075712969199 ATP2B4 1 GO:0006707 cholesterol catabolic process 1/566 11/18722 0.286642097862019 0.529075712969199 APOE 1 GO:0007042 lysosomal lumen acidification 1/566 11/18722 0.286642097862019 0.529075712969199 GRN 1 GO:0007144 female meiosis I 1/566 11/18722 0.286642097862019 0.529075712969199 CCNB2 1 GO:0009120 deoxyribonucleoside metabolic process 1/566 11/18722 0.286642097862019 0.529075712969199 TK1 1 GO:0009128 purine nucleoside monophosphate catabolic process 1/566 11/18722 0.286642097862019 0.529075712969199 DNPH1 1 GO:0010269 response to selenium ion 1/566 11/18722 0.286642097862019 0.529075712969199 GPX1 1 GO:0010739 positive regulation of protein kinase A signaling 1/566 11/18722 0.286642097862019 0.529075712969199 MIF 1 GO:0010887 negative regulation of cholesterol storage 1/566 11/18722 0.286642097862019 0.529075712969199 ABCA1 1 GO:0010918 positive regulation of mitochondrial membrane potential 1/566 11/18722 0.286642097862019 0.529075712969199 STOML2 1 GO:0014854 response to inactivity 1/566 11/18722 0.286642097862019 0.529075712969199 DAG1 1 GO:0016127 sterol catabolic process 1/566 11/18722 0.286642097862019 0.529075712969199 APOE 1 GO:0019048 modulation by virus of host process 1/566 11/18722 0.286642097862019 0.529075712969199 DAG1 1 GO:0031442 positive regulation of mRNA 3'-end processing 1/566 11/18722 0.286642097862019 0.529075712969199 CCNB1 1 GO:0032276 regulation of gonadotropin secretion 1/566 11/18722 0.286642097862019 0.529075712969199 GJA1 1 GO:0032610 interleukin-1 alpha production 1/566 11/18722 0.286642097862019 0.529075712969199 ISL1 1 GO:0032650 regulation of interleukin-1 alpha production 1/566 11/18722 0.286642097862019 0.529075712969199 ISL1 1 GO:0032957 inositol trisphosphate metabolic process 1/566 11/18722 0.286642097862019 0.529075712969199 P2RY6 1 GO:0033234 negative regulation of protein sumoylation 1/566 11/18722 0.286642097862019 0.529075712969199 PARK7 1 GO:0033483 gas homeostasis 1/566 11/18722 0.286642097862019 0.529075712969199 GSTP1 1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase 1/566 11/18722 0.286642097862019 0.529075712969199 ETFB 1 GO:0033632 regulation of cell-cell adhesion mediated by integrin 1/566 11/18722 0.286642097862019 0.529075712969199 DPP4 1 GO:0034163 regulation of toll-like receptor 9 signaling pathway 1/566 11/18722 0.286642097862019 0.529075712969199 HMGB1 1 GO:0034379 very-low-density lipoprotein particle assembly 1/566 11/18722 0.286642097862019 0.529075712969199 APOC1 1 GO:0034427 nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' 1/566 11/18722 0.286642097862019 0.529075712969199 EXOSC9 1 GO:0034776 response to histamine 1/566 11/18722 0.286642097862019 0.529075712969199 AOC1 1 GO:0042416 dopamine biosynthetic process 1/566 11/18722 0.286642097862019 0.529075712969199 PARK7 1 GO:0042447 hormone catabolic process 1/566 11/18722 0.286642097862019 0.529075712969199 SPP1 1 GO:0043312 neutrophil degranulation 1/566 11/18722 0.286642097862019 0.529075712969199 ANXA3 1 GO:0044771 meiotic cell cycle phase transition 1/566 11/18722 0.286642097862019 0.529075712969199 CCNB2 1 GO:0045060 negative thymic T cell selection 1/566 11/18722 0.286642097862019 0.529075712969199 CD74 1 GO:0045628 regulation of T-helper 2 cell differentiation 1/566 11/18722 0.286642097862019 0.529075712969199 ANXA1 1 GO:0045793 positive regulation of cell size 1/566 11/18722 0.286642097862019 0.529075712969199 HSP90AB1 1 GO:0048096 chromatin-mediated maintenance of transcription 1/566 11/18722 0.286642097862019 0.529075712969199 CDCA4 1 GO:0048102 autophagic cell death 1/566 11/18722 0.286642097862019 0.529075712969199 BNIP3 1 GO:0048635 negative regulation of muscle organ development 1/566 11/18722 0.286642097862019 0.529075712969199 YBX3 1 GO:0051081 nuclear membrane disassembly 1/566 11/18722 0.286642097862019 0.529075712969199 VRK1 1 GO:0051561 positive regulation of mitochondrial calcium ion concentration 1/566 11/18722 0.286642097862019 0.529075712969199 BNIP3 1 GO:0051573 negative regulation of histone H3-K9 methylation 1/566 11/18722 0.286642097862019 0.529075712969199 PIH1D1 1 GO:0051610 serotonin uptake 1/566 11/18722 0.286642097862019 0.529075712969199 SLC6A4 1 GO:0051657 maintenance of organelle location 1/566 11/18722 0.286642097862019 0.529075712969199 AKAP9 1 GO:0060379 cardiac muscle cell myoblast differentiation 1/566 11/18722 0.286642097862019 0.529075712969199 ISL1 1 GO:0060742 epithelial cell differentiation involved in prostate gland development 1/566 11/18722 0.286642097862019 0.529075712969199 PSAP 1 GO:0060767 epithelial cell proliferation involved in prostate gland development 1/566 11/18722 0.286642097862019 0.529075712969199 SERPINF1 1 GO:0060837 blood vessel endothelial cell differentiation 1/566 11/18722 0.286642097862019 0.529075712969199 NRP1 1 GO:0061314 Notch signaling involved in heart development 1/566 11/18722 0.286642097862019 0.529075712969199 GALNT11 1 GO:0070475 rRNA base methylation 1/566 11/18722 0.286642097862019 0.529075712969199 TRMT112 1 GO:0070778 L-aspartate transmembrane transport 1/566 11/18722 0.286642097862019 0.529075712969199 SLC1A5 1 GO:0071044 histone mRNA catabolic process 1/566 11/18722 0.286642097862019 0.529075712969199 SSB 1 GO:0071492 cellular response to UV-A 1/566 11/18722 0.286642097862019 0.529075712969199 MME 1 GO:0071888 macrophage apoptotic process 1/566 11/18722 0.286642097862019 0.529075712969199 TCP1 1 GO:0072497 mesenchymal stem cell differentiation 1/566 11/18722 0.286642097862019 0.529075712969199 KRT18 1 GO:0075522 IRES-dependent viral translational initiation 1/566 11/18722 0.286642097862019 0.529075712969199 SSB 1 GO:0090394 negative regulation of excitatory postsynaptic potential 1/566 11/18722 0.286642097862019 0.529075712969199 EIF4A3 1 GO:0090649 response to oxygen-glucose deprivation 1/566 11/18722 0.286642097862019 0.529075712969199 BNIP3 1 GO:0106049 regulation of cellular response to osmotic stress 1/566 11/18722 0.286642097862019 0.529075712969199 YBX3 1 GO:0106072 negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway 1/566 11/18722 0.286642097862019 0.529075712969199 ATP2B4 1 GO:1900112 regulation of histone H3-K9 trimethylation 1/566 11/18722 0.286642097862019 0.529075712969199 PIH1D1 1 GO:1901533 negative regulation of hematopoietic progenitor cell differentiation 1/566 11/18722 0.286642097862019 0.529075712969199 HSPA9 1 GO:1901862 negative regulation of muscle tissue development 1/566 11/18722 0.286642097862019 0.529075712969199 YBX3 1 GO:1902033 regulation of hematopoietic stem cell proliferation 1/566 11/18722 0.286642097862019 0.529075712969199 PDCD2 1 GO:1902667 regulation of axon guidance 1/566 11/18722 0.286642097862019 0.529075712969199 NRP1 1 GO:1902915 negative regulation of protein polyubiquitination 1/566 11/18722 0.286642097862019 0.529075712969199 PPIA 1 GO:1903961 positive regulation of anion transmembrane transport 1/566 11/18722 0.286642097862019 0.529075712969199 ITGB1 1 GO:1905522 negative regulation of macrophage migration 1/566 11/18722 0.286642097862019 0.529075712969199 MIF 1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity 1/566 11/18722 0.286642097862019 0.529075712969199 PKIB 1 GO:2000615 regulation of histone H3-K9 acetylation 1/566 11/18722 0.286642097862019 0.529075712969199 PIH1D1 1 GO:2000644 regulation of receptor catabolic process 1/566 11/18722 0.286642097862019 0.529075712969199 APOE 1 GO:0006333 chromatin assembly or disassembly 7/566 177/18722 0.288660372179503 0.53103207060205 NPM1/HMGB2/HMGB1/DNAJC9/ITGB3BP/HAT1/SUPT16H 7 GO:0002260 lymphocyte homeostasis 3/566 62/18722 0.288748575321315 0.53103207060205 RPS6/CD74/CCNB2 3 GO:0032623 interleukin-2 production 3/566 62/18722 0.288748575321315 0.53103207060205 RPS3/ANXA1/STOML2 3 GO:0032663 regulation of interleukin-2 production 3/566 62/18722 0.288748575321315 0.53103207060205 RPS3/ANXA1/STOML2 3 GO:0046173 polyol biosynthetic process 3/566 62/18722 0.288748575321315 0.53103207060205 IMPA2/ASAH1/P2RY6 3 GO:0048488 synaptic vesicle endocytosis 3/566 62/18722 0.288748575321315 0.53103207060205 CALM1/ACTG1/CANX 3 GO:0070265 necrotic cell death 3/566 62/18722 0.288748575321315 0.53103207060205 YBX3/BNIP3/ASAH1 3 GO:0140238 presynaptic endocytosis 3/566 62/18722 0.288748575321315 0.53103207060205 CALM1/ACTG1/CANX 3 GO:0002028 regulation of sodium ion transport 4/566 90/18722 0.289371923468233 0.53103207060205 ATP2B4/SERPINE2/GLRX/PRSS8 4 GO:0030901 midbrain development 4/566 90/18722 0.289371923468233 0.53103207060205 DYNLL1/CALM1/YWHAQ/NDUFS3 4 GO:0042475 odontogenesis of dentin-containing tooth 4/566 90/18722 0.289371923468233 0.53103207060205 LAMA5/CSF3R/SERPINE1/HTRA1 4 GO:0045638 negative regulation of myeloid cell differentiation 4/566 90/18722 0.289371923468233 0.53103207060205 FBN1/NME1/HSPA9/NME2 4 GO:0097581 lamellipodium organization 4/566 90/18722 0.289371923468233 0.53103207060205 SNX2/ARPC2/ARPC5/ITGB1 4 GO:0099175 regulation of postsynapse organization 4/566 90/18722 0.289371923468233 0.53103207060205 APOE/SRGN/SEMA3F/CFL1 4 GO:0033673 negative regulation of kinase activity 9/566 237/18722 0.290174098854304 0.532284749937933 NPM1/APOE/DNAJA1/PPIA/GSTP1/PKIB/PRDX3/PARK7/LRP5 9 GO:0050905 neuromuscular process 6/566 148/18722 0.290905282141606 0.533186626634183 GSTO1/APP/GAA/HEXB/IGDCC3/GM2A 6 GO:0097530 granulocyte migration 6/566 148/18722 0.290905282141606 0.533186626634183 CD74/CSF3R/FCER1G/ANXA1/PPIA/DPP4 6 GO:0048511 rhythmic process 11/566 298/18722 0.292269945555194 0.535467406424578 TYMS/EGFR/CDK1/PPP1CA/SLC6A4/IMPDH2/HNRNPD/SERPINF1/NAGLU/ZFHX3/ADRB1 11 GO:0006631 fatty acid metabolic process 14/566 390/18722 0.29322192149756 0.536990536613385 CD74/MIF/APOC1/ANXA1/GSTP1/ETFB/PTGES3/HPGD/GPX1/ACAT2/ECHS1/ECH1/SLC27A2/ASAH1 14 GO:0016525 negative regulation of angiogenesis 6/566 149/18722 0.296155576015373 0.539167533174842 COL4A2/ATP2B4/SPARC/SERPINF1/SERPINE1/SEMA6A 6 GO:0006816 calcium ion transport 15/566 422/18722 0.296987277980901 0.539167533174842 TPT1/CALM1/VDAC1/ATP2B4/C4orf3/CYBA/AHNAK/ITGAV/STOML2/GSTO1/SRI/GJA1/ATP2B1/P2RY6/SEC61A1 15 GO:0002704 negative regulation of leukocyte mediated immunity 3/566 63/18722 0.297043721203402 0.539167533174842 HLA-B/HLA-A/CD46 3 GO:0022617 extracellular matrix disassembly 3/566 63/18722 0.297043721203402 0.539167533174842 LRP1/LAMC1/DPP4 3 GO:0032233 positive regulation of actin filament bundle assembly 3/566 63/18722 0.297043721203402 0.539167533174842 PFN1/S100A10/NRP1 3 GO:0045143 homologous chromosome segregation 3/566 63/18722 0.297043721203402 0.539167533174842 CCNE1/PTTG1/CCNB1IP1 3 GO:0046902 regulation of mitochondrial membrane permeability 3/566 63/18722 0.297043721203402 0.539167533174842 VDAC2/SLC25A5/BNIP3 3 GO:0050854 regulation of antigen receptor-mediated signaling pathway 3/566 63/18722 0.297043721203402 0.539167533174842 RPS3/PHPT1/SLC39A10 3 GO:2000242 negative regulation of reproductive process 3/566 63/18722 0.297043721203402 0.539167533174842 SERPINF1/GJA1/CALR 3 GO:2000756 regulation of peptidyl-lysine acetylation 3/566 63/18722 0.297043721203402 0.539167533174842 ISL1/PARK7/PIH1D1 3 GO:0003203 endocardial cushion morphogenesis 2/566 36/18722 0.297196120038424 0.539167533174842 ISL1/ENG 2 GO:0003230 cardiac atrium development 2/566 36/18722 0.297196120038424 0.539167533174842 ISL1/ENG 2 GO:0009225 nucleotide-sugar metabolic process 2/566 36/18722 0.297196120038424 0.539167533174842 UGP2/NANS 2 GO:0010092 specification of animal organ identity 2/566 36/18722 0.297196120038424 0.539167533174842 LRP2/ISL1 2 GO:0014741 negative regulation of muscle hypertrophy 2/566 36/18722 0.297196120038424 0.539167533174842 ATP2B4/GLRX3 2 GO:0030224 monocyte differentiation 2/566 36/18722 0.297196120038424 0.539167533174842 CD74/HLA-DRB1 2 GO:0036314 response to sterol 2/566 36/18722 0.297196120038424 0.539167533174842 DAG1/ABCA1 2 GO:0042092 type 2 immune response 2/566 36/18722 0.297196120038424 0.539167533174842 CD74/ANXA1 2 GO:0045652 regulation of megakaryocyte differentiation 2/566 36/18722 0.297196120038424 0.539167533174842 HMGB2/SCIN 2 GO:0051955 regulation of amino acid transport 2/566 36/18722 0.297196120038424 0.539167533174842 ITGB1/SLC43A2 2 GO:0070897 transcription preinitiation complex assembly 2/566 36/18722 0.297196120038424 0.539167533174842 HMGB1/PIH1D1 2 GO:1903539 protein localization to postsynaptic membrane 2/566 36/18722 0.297196120038424 0.539167533174842 DAG1/CLSTN1 2 GO:1903749 positive regulation of establishment of protein localization to mitochondrion 2/566 36/18722 0.297196120038424 0.539167533174842 UBE2L3/PDCD5 2 GO:0071901 negative regulation of protein serine/threonine kinase activity 5/566 120/18722 0.297515709363202 0.53952746968838 APOE/DNAJA1/GSTP1/PKIB/LRP5 5 GO:0050851 antigen receptor-mediated signaling pathway 9/566 240/18722 0.302549386071183 0.541052506395262 RPS3/HLA-DRB1/HLA-A/HLA-DPB1/UBE2N/PHPT1/STOML2/SLC39A10/MNDA 9 GO:0031058 positive regulation of histone modification 4/566 92/18722 0.303001857166526 0.541052506395262 UBE2N/CCNB1/ISL1/PIH1D1 4 GO:0001838 embryonic epithelial tube formation 5/566 121/18722 0.303425586814924 0.541052506395262 PFN1/LRP2/SPINT1/PLXNB2/FOLR1 5 GO:0042752 regulation of circadian rhythm 5/566 121/18722 0.303425586814924 0.541052506395262 CDK1/PPP1CA/HNRNPD/ZFHX3/ADRB1 5 GO:0045670 regulation of osteoclast differentiation 3/566 64/18722 0.305352342518816 0.541052506395262 FBN1/TYROBP/ATP6AP1 3 GO:0070542 response to fatty acid 3/566 64/18722 0.305352342518816 0.541052506395262 NME1/CCNB1/NME2 3 GO:1903409 reactive oxygen species biosynthetic process 3/566 64/18722 0.305352342518816 0.541052506395262 CYBA/PARK7/HSPD1 3 GO:0002237 response to molecule of bacterial origin 13/566 363/18722 0.305585451031178 0.541052506395262 VIM/HMGB2/HMGB1/GSTP1/SPARC/PRDX3/HPGD/B2M/CHMP5/HSPD1/ABCA1/GJA1/SERPINE1 13 GO:0031497 chromatin assembly 6/566 151/18722 0.306710502695104 0.541052506395262 NPM1/HMGB2/HMGB1/DNAJC9/ITGB3BP/HAT1 6 GO:2000181 negative regulation of blood vessel morphogenesis 6/566 151/18722 0.306710502695104 0.541052506395262 COL4A2/ATP2B4/SPARC/SERPINF1/SERPINE1/SEMA6A 6 GO:0002024 diet induced thermogenesis 1/566 12/18722 0.308220878932518 0.541052506395262 ADRB1 1 GO:0002664 regulation of T cell tolerance induction 1/566 12/18722 0.308220878932518 0.541052506395262 HLA-B 1 GO:0002674 negative regulation of acute inflammatory response 1/566 12/18722 0.308220878932518 0.541052506395262 GSTP1 1 GO:0002863 positive regulation of inflammatory response to antigenic stimulus 1/566 12/18722 0.308220878932518 0.541052506395262 PARK7 1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition 1/566 12/18722 0.308220878932518 0.541052506395262 SRP19 1 GO:0006620 posttranslational protein targeting to endoplasmic reticulum membrane 1/566 12/18722 0.308220878932518 0.541052506395262 SEC61A1 1 GO:0007614 short-term memory 1/566 12/18722 0.308220878932518 0.541052506395262 SERPINF1 1 GO:0010459 negative regulation of heart rate 1/566 12/18722 0.308220878932518 0.541052506395262 SRI 1 GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway 1/566 12/18722 0.308220878932518 0.541052506395262 LRP1 1 GO:0010826 negative regulation of centrosome duplication 1/566 12/18722 0.308220878932518 0.541052506395262 NPM1 1 GO:0021936 regulation of cerebellar granule cell precursor proliferation 1/566 12/18722 0.308220878932518 0.541052506395262 SLC6A4 1 GO:0021978 telencephalon regionalization 1/566 12/18722 0.308220878932518 0.541052506395262 ADGRG1 1 GO:0030397 membrane disassembly 1/566 12/18722 0.308220878932518 0.541052506395262 VRK1 1 GO:0031953 negative regulation of protein autophosphorylation 1/566 12/18722 0.308220878932518 0.541052506395262 ENG 1 GO:0032908 regulation of transforming growth factor beta1 production 1/566 12/18722 0.308220878932518 0.541052506395262 TYROBP 1 GO:0033127 regulation of histone phosphorylation 1/566 12/18722 0.308220878932518 0.541052506395262 CCNB1 1 GO:0033629 negative regulation of cell adhesion mediated by integrin 1/566 12/18722 0.308220878932518 0.541052506395262 SERPINE1 1 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway 1/566 12/18722 0.308220878932518 0.541052506395262 HMGB1 1 GO:0034370 triglyceride-rich lipoprotein particle remodeling 1/566 12/18722 0.308220878932518 0.541052506395262 APOE 1 GO:0034372 very-low-density lipoprotein particle remodeling 1/566 12/18722 0.308220878932518 0.541052506395262 APOE 1 GO:0042118 endothelial cell activation 1/566 12/18722 0.308220878932518 0.541052506395262 PPIA 1 GO:0043248 proteasome assembly 1/566 12/18722 0.308220878932518 0.541052506395262 PSMG1 1 GO:0043383 negative T cell selection 1/566 12/18722 0.308220878932518 0.541052506395262 CD74 1 GO:0043476 pigment accumulation 1/566 12/18722 0.308220878932518 0.541052506395262 RAB38 1 GO:0043482 cellular pigment accumulation 1/566 12/18722 0.308220878932518 0.541052506395262 RAB38 1 GO:0043696 dedifferentiation 1/566 12/18722 0.308220878932518 0.541052506395262 HNRNPD 1 GO:0043697 cell dedifferentiation 1/566 12/18722 0.308220878932518 0.541052506395262 HNRNPD 1 GO:0044650 adhesion of symbiont to host cell 1/566 12/18722 0.308220878932518 0.541052506395262 HSP90AB1 1 GO:0045039 protein insertion into mitochondrial inner membrane 1/566 12/18722 0.308220878932518 0.541052506395262 TIMM9 1 GO:0045916 negative regulation of complement activation 1/566 12/18722 0.308220878932518 0.541052506395262 CD46 1 GO:0046606 negative regulation of centrosome cycle 1/566 12/18722 0.308220878932518 0.541052506395262 NPM1 1 GO:0048934 peripheral nervous system neuron differentiation 1/566 12/18722 0.308220878932518 0.541052506395262 ISL1 1 GO:0048935 peripheral nervous system neuron development 1/566 12/18722 0.308220878932518 0.541052506395262 ISL1 1 GO:0051001 negative regulation of nitric-oxide synthase activity 1/566 12/18722 0.308220878932518 0.541052506395262 ATP2B4 1 GO:0051340 regulation of ligase activity 1/566 12/18722 0.308220878932518 0.541052506395262 TMSB4X 1 GO:0051583 dopamine uptake involved in synaptic transmission 1/566 12/18722 0.308220878932518 0.541052506395262 PARK7 1 GO:0051639 actin filament network formation 1/566 12/18722 0.308220878932518 0.541052506395262 ARPC5 1 GO:0051934 catecholamine uptake involved in synaptic transmission 1/566 12/18722 0.308220878932518 0.541052506395262 PARK7 1 GO:0060221 retinal rod cell differentiation 1/566 12/18722 0.308220878932518 0.541052506395262 NAGLU 1 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation 1/566 12/18722 0.308220878932518 0.541052506395262 LRP1 1 GO:0060907 positive regulation of macrophage cytokine production 1/566 12/18722 0.308220878932518 0.541052506395262 CD74 1 GO:0061307 cardiac neural crest cell differentiation involved in heart development 1/566 12/18722 0.308220878932518 0.541052506395262 FOLR1 1 GO:0061308 cardiac neural crest cell development involved in heart development 1/566 12/18722 0.308220878932518 0.541052506395262 FOLR1 1 GO:0061620 glycolytic process through glucose-6-phosphate 1/566 12/18722 0.308220878932518 0.541052506395262 ENO1 1 GO:0071107 response to parathyroid hormone 1/566 12/18722 0.308220878932518 0.541052506395262 GJA1 1 GO:0071287 cellular response to manganese ion 1/566 12/18722 0.308220878932518 0.541052506395262 APP 1 GO:0071872 cellular response to epinephrine stimulus 1/566 12/18722 0.308220878932518 0.541052506395262 ATP2B4 1 GO:0072015 glomerular visceral epithelial cell development 1/566 12/18722 0.308220878932518 0.541052506395262 IQGAP1 1 GO:0072520 seminiferous tubule development 1/566 12/18722 0.308220878932518 0.541052506395262 ADGRG1 1 GO:0072711 cellular response to hydroxyurea 1/566 12/18722 0.308220878932518 0.541052506395262 RAD51 1 GO:0090331 negative regulation of platelet aggregation 1/566 12/18722 0.308220878932518 0.541052506395262 SERPINE2 1 GO:0098974 postsynaptic actin cytoskeleton organization 1/566 12/18722 0.308220878932518 0.541052506395262 ACTG1 1 GO:1901894 regulation of ATPase-coupled calcium transmembrane transporter activity 1/566 12/18722 0.308220878932518 0.541052506395262 C4orf3 1 GO:1902563 regulation of neutrophil activation 1/566 12/18722 0.308220878932518 0.541052506395262 GRN 1 GO:1902950 regulation of dendritic spine maintenance 1/566 12/18722 0.308220878932518 0.541052506395262 APOE 1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA 1/566 12/18722 0.308220878932518 0.541052506395262 EGFR 1 GO:1905245 regulation of aspartic-type peptidase activity 1/566 12/18722 0.308220878932518 0.541052506395262 GRN 1 GO:1905709 negative regulation of membrane permeability 1/566 12/18722 0.308220878932518 0.541052506395262 BNIP3 1 GO:2000035 regulation of stem cell division 1/566 12/18722 0.308220878932518 0.541052506395262 CDK2AP2 1 GO:2000508 regulation of dendritic cell chemotaxis 1/566 12/18722 0.308220878932518 0.541052506395262 CALR 1 GO:1990778 protein localization to cell periphery 12/566 333/18722 0.308221409379474 0.541052506395262 LAMA5/ATP2B4/LRP1/CDH1/EGFR/S100A10/MYL12A/ITGB1/DAG1/CLSTN1/KRT18/MACF1 12 GO:0000154 rRNA modification 2/566 37/18722 0.308443679521827 0.541052506395262 TRMT112/NHP2 2 GO:0001990 regulation of systemic arterial blood pressure by hormone 2/566 37/18722 0.308443679521827 0.541052506395262 CYBA/MME 2 GO:0002369 T cell cytokine production 2/566 37/18722 0.308443679521827 0.541052506395262 HLA-A/B2M 2 GO:0002724 regulation of T cell cytokine production 2/566 37/18722 0.308443679521827 0.541052506395262 HLA-A/B2M 2 GO:0016202 regulation of striated muscle tissue development 2/566 37/18722 0.308443679521827 0.541052506395262 YBX3/IGF2 2 GO:0032570 response to progesterone 2/566 37/18722 0.308443679521827 0.541052506395262 TYMS/TXNIP 2 GO:0032885 regulation of polysaccharide biosynthetic process 2/566 37/18722 0.308443679521827 0.541052506395262 PPP1CA/IGF2 2 GO:0042178 xenobiotic catabolic process 2/566 37/18722 0.308443679521827 0.541052506395262 GSTO1/NUDT15 2 GO:0043029 T cell homeostasis 2/566 37/18722 0.308443679521827 0.541052506395262 RPS6/CCNB2 2 GO:0048009 insulin-like growth factor receptor signaling pathway 2/566 37/18722 0.308443679521827 0.541052506395262 CRIM1/IGF1R 2 GO:0060416 response to growth hormone 2/566 37/18722 0.308443679521827 0.541052506395262 CACYBP/NME2 2 GO:0062237 protein localization to postsynapse 2/566 37/18722 0.308443679521827 0.541052506395262 DAG1/CLSTN1 2 GO:0019730 antimicrobial humoral response 5/566 122/18722 0.309353177738818 0.541488471471049 GAPDH/LYZ/HLA-A/HMGN2/RPS19 5 GO:0050868 negative regulation of T cell activation 5/566 122/18722 0.309353177738818 0.541488471471049 CD74/HMGB1/HLA-DRB1/ANXA1/GPNMB 5 GO:0051928 positive regulation of calcium ion transport 5/566 122/18722 0.309353177738818 0.541488471471049 CALM1/GSTO1/SRI/ATP2B1/P2RY6 5 GO:0072329 monocarboxylic acid catabolic process 5/566 122/18722 0.309353177738818 0.541488471471049 ETFB/ACAT2/ECHS1/ECH1/SLC27A2 5 GO:1990266 neutrophil migration 5/566 122/18722 0.309353177738818 0.541488471471049 CD74/CSF3R/FCER1G/PPIA/DPP4 5 GO:1903131 mononuclear cell differentiation 15/566 426/18722 0.309421983697742 0.541488471471049 RPS6/CD74/HLA-B/LGALS1/HMGB1/HLA-DRB1/FCER1G/ANXA1/HLA-DRA/SLC25A5/B2M/ITGB8/ITGB1/CD46/CLPTM1 15 GO:1902807 negative regulation of cell cycle G1/S phase transition 4/566 93/18722 0.309843913992554 0.542013793750433 RPL26/TRIAP1/CDK2AP2/GPNMB 4 GO:0060070 canonical Wnt signaling pathway 11/566 303/18722 0.310725257444341 0.543342044831975 APOE/EGFR/ISL1/LGR5/PPP1CA/AMFR/PLPP3/LRP5/RUVBL1/FOLR1/ZNRF3 11 GO:0030509 BMP signaling pathway 6/566 152/18722 0.312012805516555 0.544752959789113 FBN1/LRP2/CRIM1/FSTL1/ENG/HTRA1 6 GO:0031056 regulation of histone modification 6/566 152/18722 0.312012805516555 0.544752959789113 UBE2N/CCNB1/ISL1/PARK7/IGF2/PIH1D1 6 GO:1901343 negative regulation of vasculature development 6/566 152/18722 0.312012805516555 0.544752959789113 COL4A2/ATP2B4/SPARC/SERPINF1/SERPINE1/SEMA6A 6 GO:0006469 negative regulation of protein kinase activity 8/566 212/18722 0.312143935404768 0.544752959789113 NPM1/APOE/DNAJA1/PPIA/GSTP1/PKIB/PARK7/LRP5 8 GO:0030258 lipid modification 8/566 212/18722 0.312143935404768 0.544752959789113 APOC1/APOE/ETFB/ACAT2/ECHS1/PLPP3/ECH1/SLC27A2 8 GO:0002720 positive regulation of cytokine production involved in immune response 3/566 65/18722 0.313670186091023 0.546559557133946 CD74/HLA-A/B2M 3 GO:0048645 animal organ formation 3/566 65/18722 0.313670186091023 0.546559557133946 LRP2/ISL1/FOLR1 3 GO:0051310 metaphase plate congression 3/566 65/18722 0.313670186091023 0.546559557133946 CCNB1/NUDC/CHMP5 3 GO:1902475 L-alpha-amino acid transmembrane transport 3/566 65/18722 0.313670186091023 0.546559557133946 ITGB1/SLC43A2/SLC1A5 3 GO:0071482 cellular response to light stimulus 5/566 123/18722 0.315296859690015 0.549179037300449 NPM1/RPL26/TRIAP1/PBK/MME 5 GO:0002042 cell migration involved in sprouting angiogenesis 4/566 94/18722 0.316700747712296 0.551193013610297 ANXA1/NRP1/ITGB1/PDCD10 4 GO:0030316 osteoclast differentiation 4/566 94/18722 0.316700747712296 0.551193013610297 FBN1/TYROBP/ATP6AP1/TFRC 4 GO:0034765 regulation of ion transmembrane transport 17/566 491/18722 0.317723877792573 0.552757602161991 CALM1/VDAC1/ATP2B4/C4orf3/CYBA/YWHAQ/PARK7/AHNAK/TMSB4X/ITGB1/AKAP9/GSTO1/APP/GLRX/SRI/SLC43A2/P2RY6 17 GO:0009615 response to virus 13/566 367/18722 0.319154728894915 0.554383673250141 TPT1/PSMA2/ENO1/STMN1/CCT5/BANF1/RPS15A/IFITM2/CFL1/ITGB8/BNIP3/GTF2F1/HTRA1 13 GO:0006882 cellular zinc ion homeostasis 2/566 38/18722 0.319654737024508 0.554383673250141 MT2A/SLC39A10 2 GO:0010742 macrophage derived foam cell differentiation 2/566 38/18722 0.319654737024508 0.554383673250141 ITGAV/ABCA1 2 GO:0032717 negative regulation of interleukin-8 production 2/566 38/18722 0.319654737024508 0.554383673250141 ANXA1/TMSB4X 2 GO:0032941 secretion by tissue 2/566 38/18722 0.319654737024508 0.554383673250141 CYBA/EGFR 2 GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway 2/566 38/18722 0.319654737024508 0.554383673250141 ISL1/CALR 2 GO:0046329 negative regulation of JNK cascade 2/566 38/18722 0.319654737024508 0.554383673250141 DNAJA1/GSTP1 2 GO:0090077 foam cell differentiation 2/566 38/18722 0.319654737024508 0.554383673250141 ITGAV/ABCA1 2 GO:0072330 monocarboxylic acid biosynthetic process 8/566 214/18722 0.321114697968711 0.555063267515535 CD74/MIF/APOC1/ANXA1/GSTP1/PTGES3/PARK7/SLC27A2 8 GO:0019229 regulation of vasoconstriction 3/566 66/18722 0.32199311778244 0.555063267515535 EGFR/GJA1/ATP2B1 3 GO:0030193 regulation of blood coagulation 3/566 66/18722 0.32199311778244 0.555063267515535 APOE/SERPINE2/SERPINE1 3 GO:0071300 cellular response to retinoic acid 3/566 66/18722 0.32199311778244 0.555063267515535 SLC6A4/ABCA1/SERPINF1 3 GO:1905953 negative regulation of lipid localization 3/566 66/18722 0.32199311778244 0.555063267515535 APOC1/ITGAV/ABCA1 3 GO:0007265 Ras protein signal transduction 12/566 337/18722 0.322443158632328 0.555063267515535 APOE/STMN1/ADGRG1/PARK7/CFL1/MET/NRP1/ITGB1/CCNA2/GABARAP/ABCA1/AIF1 12 GO:0032386 regulation of intracellular transport 12/566 337/18722 0.322443158632328 0.555063267515535 RAN/HSP90AB1/NUTF2/UBE2L3/CDH1/CDK1/OAZ1/PARK7/TXN/PDCD10/PDCD5/LMAN1 12 GO:0007605 sensory perception of sound 6/566 154/18722 0.322661303472138 0.555063267515535 LRP2/BIRC5/GPX1/RPL38/HEXB/TIMM9 6 GO:0002532 production of molecular mediator involved in inflammatory response 4/566 95/18722 0.323569942880032 0.555063267515535 RPS19/GRN/PLD3/SERPINE1 4 GO:0008593 regulation of Notch signaling pathway 4/566 95/18722 0.323569942880032 0.555063267515535 IL6ST/PDCD10/CD46/GALNT11 4 GO:0032479 regulation of type I interferon production 4/566 95/18722 0.323569942880032 0.555063267515535 GAPDH/HMGB2/HMGB1/HSPD1 4 GO:0032606 type I interferon production 4/566 95/18722 0.323569942880032 0.555063267515535 GAPDH/HMGB2/HMGB1/HSPD1 4 GO:0018210 peptidyl-threonine modification 5/566 125/18722 0.327226078372466 0.555063267515535 CALM1/CDK1/VRK1/APP/GALNT11 5 GO:0051053 negative regulation of DNA metabolic process 5/566 125/18722 0.327226078372466 0.555063267515535 RPS3/HNRNPA1/HNRNPC/SUB1/GJA1 5 GO:1904375 regulation of protein localization to cell periphery 5/566 125/18722 0.327226078372466 0.555063267515535 ATP2B4/LRP1/EGFR/ITGB1/DAG1 5 GO:0002040 sprouting angiogenesis 7/566 185/18722 0.327254602128384 0.555063267515535 HMGB1/ANXA1/PKM/NRP1/ITGB1/PDCD10/SEMA6A 7 GO:0001682 tRNA 5'-leader removal 1/566 13/18722 0.329148029254495 0.555063267515535 SSB 1 GO:0001886 endothelial cell morphogenesis 1/566 13/18722 0.329148029254495 0.555063267515535 MET 1 GO:0003222 ventricular trabecula myocardium morphogenesis 1/566 13/18722 0.329148029254495 0.555063267515535 ENG 1 GO:0005513 detection of calcium ion 1/566 13/18722 0.329148029254495 0.555063267515535 CALM1 1 GO:0006000 fructose metabolic process 1/566 13/18722 0.329148029254495 0.555063267515535 ALDOA 1 GO:0006264 mitochondrial DNA replication 1/566 13/18722 0.329148029254495 0.555063267515535 STOML2 1 GO:0006361 transcription initiation from RNA polymerase I promoter 1/566 13/18722 0.329148029254495 0.555063267515535 PIH1D1 1 GO:0006995 cellular response to nitrogen starvation 1/566 13/18722 0.329148029254495 0.555063267515535 GABARAP 1 GO:0007494 midgut development 1/566 13/18722 0.329148029254495 0.555063267515535 EGFR 1 GO:0007567 parturition 1/566 13/18722 0.329148029254495 0.555063267515535 HPGD 1 GO:0009650 UV protection 1/566 13/18722 0.329148029254495 0.555063267515535 GPX1 1 GO:0010917 negative regulation of mitochondrial membrane potential 1/566 13/18722 0.329148029254495 0.555063267515535 BNIP3 1 GO:0010960 magnesium ion homeostasis 1/566 13/18722 0.329148029254495 0.555063267515535 EGFR 1 GO:0014745 negative regulation of muscle adaptation 1/566 13/18722 0.329148029254495 0.555063267515535 ATP2B4 1 GO:0016078 tRNA catabolic process 1/566 13/18722 0.329148029254495 0.555063267515535 EXOSC9 1 GO:0016322 neuron remodeling 1/566 13/18722 0.329148029254495 0.555063267515535 APP 1 GO:0018202 peptidyl-histidine modification 1/566 13/18722 0.329148029254495 0.555063267515535 NME2 1 GO:0018206 peptidyl-methionine modification 1/566 13/18722 0.329148029254495 0.555063267515535 NAA20 1 GO:0021554 optic nerve development 1/566 13/18722 0.329148029254495 0.555063267515535 RPL24 1 GO:0021681 cerebellar granular layer development 1/566 13/18722 0.329148029254495 0.555063267515535 SERPINE2 1 GO:0021819 layer formation in cerebral cortex 1/566 13/18722 0.329148029254495 0.555063267515535 ADGRG1 1 GO:0031053 primary miRNA processing 1/566 13/18722 0.329148029254495 0.555063267515535 HNRNPA2B1 1 GO:0032905 transforming growth factor beta1 production 1/566 13/18722 0.329148029254495 0.555063267515535 TYROBP 1 GO:0033262 regulation of nuclear cell cycle DNA replication 1/566 13/18722 0.329148029254495 0.555063267515535 DBF4 1 GO:0033689 negative regulation of osteoblast proliferation 1/566 13/18722 0.329148029254495 0.555063267515535 PLXNB1 1 GO:0034309 primary alcohol biosynthetic process 1/566 13/18722 0.329148029254495 0.555063267515535 PARK7 1 GO:0034982 mitochondrial protein processing 1/566 13/18722 0.329148029254495 0.555063267515535 STOML2 1 GO:0036302 atrioventricular canal development 1/566 13/18722 0.329148029254495 0.555063267515535 ENG 1 GO:0043562 cellular response to nitrogen levels 1/566 13/18722 0.329148029254495 0.555063267515535 GABARAP 1 GO:0043928 exonucleolytic catabolism of deadenylated mRNA 1/566 13/18722 0.329148029254495 0.555063267515535 EXOSC9 1 GO:0043970 histone H3-K9 acetylation 1/566 13/18722 0.329148029254495 0.555063267515535 PIH1D1 1 GO:0044090 positive regulation of vacuole organization 1/566 13/18722 0.329148029254495 0.555063267515535 GRN 1 GO:0046512 sphingosine biosynthetic process 1/566 13/18722 0.329148029254495 0.555063267515535 ASAH1 1 GO:0046520 sphingoid biosynthetic process 1/566 13/18722 0.329148029254495 0.555063267515535 ASAH1 1 GO:0046689 response to mercury ion 1/566 13/18722 0.329148029254495 0.555063267515535 PARK7 1 GO:0048207 vesicle targeting, rough ER to cis-Golgi 1/566 13/18722 0.329148029254495 0.555063267515535 TFG 1 GO:0048208 COPII vesicle coating 1/566 13/18722 0.329148029254495 0.555063267515535 TFG 1 GO:0051451 myoblast migration 1/566 13/18722 0.329148029254495 0.555063267515535 ANXA1 1 GO:0051956 negative regulation of amino acid transport 1/566 13/18722 0.329148029254495 0.555063267515535 SLC43A2 1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore 1/566 13/18722 0.329148029254495 0.555063267515535 CCNB1 1 GO:0060670 branching involved in labyrinthine layer morphogenesis 1/566 13/18722 0.329148029254495 0.555063267515535 SPINT1 1 GO:0061615 glycolytic process through fructose-6-phosphate 1/566 13/18722 0.329148029254495 0.555063267515535 ENO1 1 GO:0061744 motor behavior 1/566 13/18722 0.329148029254495 0.555063267515535 DPP4 1 GO:0071027 nuclear RNA surveillance 1/566 13/18722 0.329148029254495 0.555063267515535 EXOSC9 1 GO:0071028 nuclear mRNA surveillance 1/566 13/18722 0.329148029254495 0.555063267515535 EXOSC9 1 GO:0071696 ectodermal placode development 1/566 13/18722 0.329148029254495 0.555063267515535 NRP1 1 GO:0072310 glomerular epithelial cell development 1/566 13/18722 0.329148029254495 0.555063267515535 IQGAP1 1 GO:0072578 neurotransmitter-gated ion channel clustering 1/566 13/18722 0.329148029254495 0.555063267515535 APOE 1 GO:0072710 response to hydroxyurea 1/566 13/18722 0.329148029254495 0.555063267515535 RAD51 1 GO:0090042 tubulin deacetylation 1/566 13/18722 0.329148029254495 0.555063267515535 BEX4 1 GO:0106070 regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway 1/566 13/18722 0.329148029254495 0.555063267515535 ATP2B4 1 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors 1/566 13/18722 0.329148029254495 0.555063267515535 TIMP3 1 GO:1902947 regulation of tau-protein kinase activity 1/566 13/18722 0.329148029254495 0.555063267515535 HSP90AB1 1 GO:1903054 negative regulation of extracellular matrix organization 1/566 13/18722 0.329148029254495 0.555063267515535 DPP4 1 GO:1903977 positive regulation of glial cell migration 1/566 13/18722 0.329148029254495 0.555063267515535 LRP1 1 GO:1904925 positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization 1/566 13/18722 0.329148029254495 0.555063267515535 VPS13C 1 GO:1990403 embryonic brain development 1/566 13/18722 0.329148029254495 0.555063267515535 RPL10 1 GO:0002377 immunoglobulin production 8/566 216/18722 0.330133033228724 0.555779665982362 HLA-DRB1/HLA-DPA1/HLA-DRA/HLA-DPB1/B2M/HSPD1/CTNNBL1/TFRC 8 GO:0016445 somatic diversification of immunoglobulins 3/566 67/18722 0.330317122965195 0.555779665982362 HSPD1/CTNNBL1/TFRC 3 GO:0003073 regulation of systemic arterial blood pressure 4/566 96/18722 0.330449123065522 0.555779665982362 CYBA/GJA1/MME/ADRB1 4 GO:0034620 cellular response to unfolded protein 4/566 96/18722 0.330449123065522 0.555779665982362 HSPA9/HSPD1/AMFR/COPS5 4 GO:0016233 telomere capping 2/566 39/18722 0.330821229751406 0.555779665982362 PKIB/HNRNPD 2 GO:0032728 positive regulation of interferon-beta production 2/566 39/18722 0.330821229751406 0.555779665982362 HMGB2/HMGB1 2 GO:0045923 positive regulation of fatty acid metabolic process 2/566 39/18722 0.330821229751406 0.555779665982362 CD74/ANXA1 2 GO:0071548 response to dexamethasone 2/566 39/18722 0.330821229751406 0.555779665982362 EGFR/SERPINF1 2 GO:1901861 regulation of muscle tissue development 2/566 39/18722 0.330821229751406 0.555779665982362 YBX3/IGF2 2 GO:2000249 regulation of actin cytoskeleton reorganization 2/566 39/18722 0.330821229751406 0.555779665982362 PHPT1/NRP1 2 GO:0008217 regulation of blood pressure 7/566 186/18722 0.332139626411565 0.557573761985025 CYBA/LRP5/HBB/GJA1/ATP2B1/MME/ADRB1 7 GO:0071478 cellular response to radiation 7/566 186/18722 0.332139626411565 0.557573761985025 NPM1/RPL26/CYBA/TRIAP1/RAD51/PBK/MME 7 GO:0046631 alpha-beta T cell activation 6/566 156/18722 0.333360680138327 0.559412645298089 HMGB1/HLA-DRB1/HLA-A/ANXA1/HLA-DRA/STOML2 6 GO:0060537 muscle tissue development 14/566 403/18722 0.335597482586784 0.56295402881551 LRP2/YBX3/CSRP2/CCNB1/ISL1/CACYBP/CDK1/GPX1/ITGB1/ENG/IGF2/GJA1/DSG2/CALR 14 GO:0021537 telencephalon development 9/566 248/18722 0.336111359447457 0.563603680700594 ATP2B4/LRP1/NME1/SLC2A1/ADGRG1/LAMB1/ANXA3/SLC38A2/BNIP3 9 GO:0008064 regulation of actin polymerization or depolymerization 7/566 187/18722 0.337035253889088 0.564940116835173 PFN1/TMSB10/ARPC2/ARPC5/TMSB4X/ARPC1A/SCIN 7 GO:0061912 selective autophagy 3/566 68/18722 0.338638306742157 0.566921375100966 VDAC1/SLC25A5/VPS13C 3 GO:1900046 regulation of hemostasis 3/566 68/18722 0.338638306742157 0.566921375100966 APOE/SERPINE2/SERPINE1 3 GO:0070646 protein modification by small protein removal 6/566 157/18722 0.338726607764728 0.566921375100966 CDK1/PARK7/UBXN1/PSMD14/UCHL3/COPS5 6 GO:1990845 adaptive thermogenesis 6/566 157/18722 0.338726607764728 0.566921375100966 SLC25A5/PRLR/FH/GJA1/IGF1R/ADRB1 6 GO:0030048 actin filament-based movement 5/566 127/18722 0.339200561628319 0.567288091799128 AKAP9/DSC2/SRI/GJA1/DSG2 5 GO:0051224 negative regulation of protein transport 5/566 127/18722 0.339200561628319 0.567288091799128 APOE/ANXA1/PARK7/TXN/LMAN1 5 GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 9/566 249/18722 0.340353952638236 0.567367284648001 GAPDH/CD74/LGALS1/HLA-DRB1/GSTP1/UBE2N/TFG/GJA1/TFRC 9 GO:1901988 negative regulation of cell cycle phase transition 9/566 249/18722 0.340353952638236 0.567367284648001 RPL26/MAD2L1/CCNB1/CDK1/BUB3/TRIAP1/CDK2AP2/ZWINT/GPNMB 9 GO:0006730 one-carbon metabolic process 2/566 40/18722 0.341935614045358 0.567367284648001 TYMS/MTHFS 2 GO:0030501 positive regulation of bone mineralization 2/566 40/18722 0.341935614045358 0.567367284648001 FBN2/ATP2B1 2 GO:0031297 replication fork processing 2/566 40/18722 0.341935614045358 0.567367284648001 ALYREF/RAD51 2 GO:0043001 Golgi to plasma membrane protein transport 2/566 40/18722 0.341935614045358 0.567367284648001 KRT18/MACF1 2 GO:0045777 positive regulation of blood pressure 2/566 40/18722 0.341935614045358 0.567367284648001 CYBA/ADRB1 2 GO:0055069 zinc ion homeostasis 2/566 40/18722 0.341935614045358 0.567367284648001 MT2A/SLC39A10 2 GO:0071276 cellular response to cadmium ion 2/566 40/18722 0.341935614045358 0.567367284648001 EGFR/MT2A 2 GO:0030832 regulation of actin filament length 7/566 188/18722 0.341940624947046 0.567367284648001 PFN1/TMSB10/ARPC2/ARPC5/TMSB4X/ARPC1A/SCIN 7 GO:0030098 lymphocyte differentiation 13/566 374/18722 0.343237892539653 0.567367284648001 RPS6/CD74/LGALS1/HMGB1/HLA-DRB1/FCER1G/ANXA1/HLA-DRA/SLC25A5/B2M/ITGB1/CD46/CLPTM1 13 GO:0034764 positive regulation of transmembrane transport 8/566 219/18722 0.343737747276197 0.567367284648001 CALM1/TMSB4X/ITGB1/AKAP9/GSTO1/GLRX/SRI/P2RY6 8 GO:0032496 response to lipopolysaccharide 12/566 343/18722 0.344046595256287 0.567367284648001 VIM/HMGB2/HMGB1/GSTP1/SPARC/PRDX3/HPGD/CHMP5/HSPD1/ABCA1/GJA1/SERPINE1 12 GO:0006470 protein dephosphorylation 10/566 281/18722 0.344833463723836 0.567367284648001 CALM1/HSP90AB1/PPIA/PTPRF/PHPT1/PPP1CA/PPM1G/PPP4C/HSP90B1/SLC39A10 10 GO:0007249 I-kappaB kinase/NF-kappaB signaling 10/566 281/18722 0.344833463723836 0.567367284648001 GAPDH/CD74/LGALS1/HLA-DRB1/GSTP1/UBE2N/TFG/GJA1/FAIM/TFRC 10 GO:0035303 regulation of dephosphorylation 5/566 128/18722 0.345200886922659 0.567367284648001 CALM1/HSP90AB1/PPIA/HSP90B1/SLC39A10 5 GO:0002253 activation of immune response 13/566 375/18722 0.3467085899103 0.567367284648001 RPS3/HMGB1/HLA-DRB1/TYROBP/FCER1G/HLA-A/HLA-DPB1/UBE2N/PHPT1/STOML2/CD46/SLC39A10/MNDA 13 GO:0006368 transcription elongation from RNA polymerase II promoter 3/566 69/18722 0.346952893936237 0.567367284648001 SUPT16H/CDCA4/GTF2F1 3 GO:0010611 regulation of cardiac muscle hypertrophy 3/566 69/18722 0.346952893936237 0.567367284648001 ATP2B4/IL6ST/GLRX3 3 GO:0050810 regulation of steroid biosynthetic process 3/566 69/18722 0.346952893936237 0.567367284648001 APOE/CGA/ASAH1 3 GO:0060193 positive regulation of lipase activity 3/566 69/18722 0.346952893936237 0.567367284648001 FLT1/EGFR/P2RY6 3 GO:0070192 chromosome organization involved in meiotic cell cycle 3/566 69/18722 0.346952893936237 0.567367284648001 CCNE1/RAD51/CCNB1IP1 3 GO:0006302 double-strand break repair 9/566 251/18722 0.348864574194445 0.567367284648001 HMGB2/HMGB1/UBE2N/DEK/RPA3/RAD51/PPP4C/PSMD14/UBE2V2 9 GO:0000212 meiotic spindle organization 1/566 14/18722 0.349443192835763 0.567367284648001 CCNB2 1 GO:0002475 antigen processing and presentation via MHC class Ib 1/566 14/18722 0.349443192835763 0.567367284648001 B2M 1 GO:0002517 T cell tolerance induction 1/566 14/18722 0.349443192835763 0.567367284648001 HLA-B 1 GO:0002829 negative regulation of type 2 immune response 1/566 14/18722 0.349443192835763 0.567367284648001 ANXA1 1 GO:0002864 regulation of acute inflammatory response to antigenic stimulus 1/566 14/18722 0.349443192835763 0.567367284648001 PARK7 1 GO:0007100 mitotic centrosome separation 1/566 14/18722 0.349443192835763 0.567367284648001 RANBP1 1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity 1/566 14/18722 0.349443192835763 0.567367284648001 PRLR 1 GO:0009071 serine family amino acid catabolic process 1/566 14/18722 0.349443192835763 0.567367284648001 GCSH 1 GO:0009159 deoxyribonucleoside monophosphate catabolic process 1/566 14/18722 0.349443192835763 0.567367284648001 DNPH1 1 GO:0009173 pyrimidine ribonucleoside monophosphate metabolic process 1/566 14/18722 0.349443192835763 0.567367284648001 UMPS 1 GO:0010771 negative regulation of cell morphogenesis involved in differentiation 1/566 14/18722 0.349443192835763 0.567367284648001 FBLN1 1 GO:0014874 response to stimulus involved in regulation of muscle adaptation 1/566 14/18722 0.349443192835763 0.567367284648001 DAG1 1 GO:0031115 negative regulation of microtubule polymerization 1/566 14/18722 0.349443192835763 0.567367284648001 STMN1 1 GO:0034111 negative regulation of homotypic cell-cell adhesion 1/566 14/18722 0.349443192835763 0.567367284648001 SERPINE2 1 GO:0034616 response to laminar fluid shear stress 1/566 14/18722 0.349443192835763 0.567367284648001 ABCA1 1 GO:0035437 maintenance of protein localization in endoplasmic reticulum 1/566 14/18722 0.349443192835763 0.567367284648001 GJA1 1 GO:0035563 positive regulation of chromatin binding 1/566 14/18722 0.349443192835763 0.567367284648001 GMNN 1 GO:0035589 G protein-coupled purinergic nucleotide receptor signaling pathway 1/566 14/18722 0.349443192835763 0.567367284648001 P2RY6 1 GO:0035672 oligopeptide transmembrane transport 1/566 14/18722 0.349443192835763 0.567367284648001 GJA1 1 GO:0035791 platelet-derived growth factor receptor-beta signaling pathway 1/566 14/18722 0.349443192835763 0.567367284648001 LRP1 1 GO:0036295 cellular response to increased oxygen levels 1/566 14/18722 0.349443192835763 0.567367284648001 ATP6AP1 1 GO:0036444 calcium import into the mitochondrion 1/566 14/18722 0.349443192835763 0.567367284648001 VDAC1 1 GO:0045059 positive thymic T cell selection 1/566 14/18722 0.349443192835763 0.567367284648001 CD74 1 GO:0045472 response to ether 1/566 14/18722 0.349443192835763 0.567367284648001 HNRNPD 1 GO:0045837 negative regulation of membrane potential 1/566 14/18722 0.349443192835763 0.567367284648001 BNIP3 1 GO:0045989 positive regulation of striated muscle contraction 1/566 14/18722 0.349443192835763 0.567367284648001 GSTO1 1 GO:0046049 UMP metabolic process 1/566 14/18722 0.349443192835763 0.567367284648001 UMPS 1 GO:0047484 regulation of response to osmotic stress 1/566 14/18722 0.349443192835763 0.567367284648001 YBX3 1 GO:0048291 isotype switching to IgG isotypes 1/566 14/18722 0.349443192835763 0.567367284648001 HSPD1 1 GO:0048681 negative regulation of axon regeneration 1/566 14/18722 0.349443192835763 0.567367284648001 SPP1 1 GO:0051645 Golgi localization 1/566 14/18722 0.349443192835763 0.567367284648001 PDCD10 1 GO:0051917 regulation of fibrinolysis 1/566 14/18722 0.349443192835763 0.567367284648001 SERPINE1 1 GO:0051984 positive regulation of chromosome segregation 1/566 14/18722 0.349443192835763 0.567367284648001 CCNB1 1 GO:0060081 membrane hyperpolarization 1/566 14/18722 0.349443192835763 0.567367284648001 PARK7 1 GO:0060732 positive regulation of inositol phosphate biosynthetic process 1/566 14/18722 0.349443192835763 0.567367284648001 P2RY6 1 GO:0060841 venous blood vessel development 1/566 14/18722 0.349443192835763 0.567367284648001 ENG 1 GO:0060911 cardiac cell fate commitment 1/566 14/18722 0.349443192835763 0.567367284648001 ISL1 1 GO:0061043 regulation of vascular wound healing 1/566 14/18722 0.349443192835763 0.567367284648001 SERPINE1 1 GO:0070278 extracellular matrix constituent secretion 1/566 14/18722 0.349443192835763 0.567367284648001 ENG 1 GO:0070307 lens fiber cell development 1/566 14/18722 0.349443192835763 0.567367284648001 VIM 1 GO:0071236 cellular response to antibiotic 1/566 14/18722 0.349443192835763 0.567367284648001 RPL23 1 GO:0071415 cellular response to purine-containing compound 1/566 14/18722 0.349443192835763 0.567367284648001 P2RY6 1 GO:0086103 G protein-coupled receptor signaling pathway involved in heart process 1/566 14/18722 0.349443192835763 0.567367284648001 ATP2B4 1 GO:0090239 regulation of histone H4 acetylation 1/566 14/18722 0.349443192835763 0.567367284648001 PIH1D1 1 GO:0090281 negative regulation of calcium ion import 1/566 14/18722 0.349443192835763 0.567367284648001 VDAC1 1 GO:0099188 postsynaptic cytoskeleton organization 1/566 14/18722 0.349443192835763 0.567367284648001 ACTG1 1 GO:1900025 negative regulation of substrate adhesion-dependent cell spreading 1/566 14/18722 0.349443192835763 0.567367284648001 FBLN1 1 GO:1901077 regulation of relaxation of muscle 1/566 14/18722 0.349443192835763 0.567367284648001 SRI 1 GO:1901857 positive regulation of cellular respiration 1/566 14/18722 0.349443192835763 0.567367284648001 PARK7 1 GO:1902036 regulation of hematopoietic stem cell differentiation 1/566 14/18722 0.349443192835763 0.567367284648001 HSPA9 1 GO:1902916 positive regulation of protein polyubiquitination 1/566 14/18722 0.349443192835763 0.567367284648001 GABARAP 1 GO:1902969 mitotic DNA replication 1/566 14/18722 0.349443192835763 0.567367284648001 RAD51 1 GO:1903894 regulation of IRE1-mediated unfolded protein response 1/566 14/18722 0.349443192835763 0.567367284648001 COPS5 1 GO:1904294 positive regulation of ERAD pathway 1/566 14/18722 0.349443192835763 0.567367284648001 TMEM259 1 GO:1904923 regulation of autophagy of mitochondrion in response to mitochondrial depolarization 1/566 14/18722 0.349443192835763 0.567367284648001 VPS13C 1 GO:1905065 positive regulation of vascular associated smooth muscle cell differentiation 1/566 14/18722 0.349443192835763 0.567367284648001 ENG 1 GO:1905208 negative regulation of cardiocyte differentiation 1/566 14/18722 0.349443192835763 0.567367284648001 EGFR 1 GO:0021549 cerebellum development 4/566 99/18722 0.351123418047775 0.569609307748369 SERPINE2/HNRNPD/AIF1/NAGLU 4 GO:0033209 tumor necrosis factor-mediated signaling pathway 4/566 99/18722 0.351123418047775 0.569609307748369 GSTP1/KRT8/TMSB4X/KRT18 4 GO:0006334 nucleosome assembly 5/566 129/18722 0.351207895276117 0.569609307748369 NPM1/HMGB2/DNAJC9/ITGB3BP/HAT1 5 GO:0001953 negative regulation of cell-matrix adhesion 2/566 41/18722 0.352990841462276 0.570422949615264 LRP1/SERPINE1 2 GO:0009167 purine ribonucleoside monophosphate metabolic process 2/566 41/18722 0.352990841462276 0.570422949615264 IMPDH2/GMPS 2 GO:0010907 positive regulation of glucose metabolic process 2/566 41/18722 0.352990841462276 0.570422949615264 HMGB1/IGF2 2 GO:0048634 regulation of muscle organ development 2/566 41/18722 0.352990841462276 0.570422949615264 YBX3/IGF2 2 GO:0050856 regulation of T cell receptor signaling pathway 2/566 41/18722 0.352990841462276 0.570422949615264 RPS3/PHPT1 2 GO:0055023 positive regulation of cardiac muscle tissue growth 2/566 41/18722 0.352990841462276 0.570422949615264 CCNB1/CDK1 2 GO:0071470 cellular response to osmotic stress 2/566 41/18722 0.352990841462276 0.570422949615264 YBX3/SLC2A1 2 GO:1900371 regulation of purine nucleotide biosynthetic process 2/566 41/18722 0.352990841462276 0.570422949615264 ENO1/TMSB4X 2 GO:1902622 regulation of neutrophil migration 2/566 41/18722 0.352990841462276 0.570422949615264 CD74/DPP4 2 GO:2000008 regulation of protein localization to cell surface 2/566 41/18722 0.352990841462276 0.570422949615264 HSP90AB1/TYROBP 2 GO:0060402 calcium ion transport into cytosol 6/566 160/18722 0.354875907791095 0.573261081816385 CALM1/ATP2B4/CYBA/GSTO1/SRI/P2RY6 6 GO:0003407 neural retina development 3/566 70/18722 0.355257228864973 0.573460907507926 ATP2B4/NAGLU/ATP2B1 3 GO:0060415 muscle tissue morphogenesis 3/566 70/18722 0.355257228864973 0.573460907507926 LRP2/ISL1/ENG 3 GO:0002768 immune response-regulating cell surface receptor signaling pathway 11/566 315/18722 0.356049103731765 0.5745308480659 RPS3/HLA-DRB1/TYROBP/FCER1G/HLA-A/HLA-DPB1/UBE2N/PHPT1/STOML2/SLC39A10/MNDA 11 GO:0072659 protein localization to plasma membrane 10/566 284/18722 0.356899848976367 0.575694973783618 LAMA5/ATP2B4/LRP1/CDH1/EGFR/S100A10/MYL12A/ITGB1/KRT18/MACF1 10 GO:0006352 DNA-templated transcription, initiation 5/566 130/18722 0.357220080647907 0.575794279161652 HMGB1/SUB1/MED4/PIH1D1/GTF2F1 5 GO:0042476 odontogenesis 5/566 130/18722 0.357220080647907 0.575794279161652 LAMA5/CSF3R/LAMB1/SERPINE1/HTRA1 5 GO:0060828 regulation of canonical Wnt signaling pathway 9/566 253/18722 0.357405415991942 0.575884513932727 APOE/EGFR/ISL1/LGR5/PPP1CA/AMFR/RUVBL1/FOLR1/ZNRF3 9 GO:0019218 regulation of steroid metabolic process 4/566 100/18722 0.358019592399113 0.576456862698319 APOC1/APOE/CGA/ASAH1 4 GO:0045807 positive regulation of endocytosis 4/566 100/18722 0.358019592399113 0.576456862698319 APOE/LRP1/B2M/SERPINE1 4 GO:0006936 muscle contraction 12/566 347/18722 0.358597591528179 0.577178769878327 CALM1/ALDOA/ENO1/ATP2B4/AKAP9/GSTO1/DSC2/GAA/SRI/GJA1/ATP2B1/DSG2 12 GO:0019079 viral genome replication 5/566 131/18722 0.363235956599434 0.580479894563327 PPIA/BANF1/DEK/IFITM2/PPIH 5 GO:0045089 positive regulation of innate immune response 5/566 131/18722 0.363235956599434 0.580479894563327 HMGB2/HMGB1/TYROBP/RPS19/MNDA 5 GO:0003208 cardiac ventricle morphogenesis 3/566 71/18722 0.363547774916504 0.580479894563327 LRP2/ISL1/ENG 3 GO:0071230 cellular response to amino acid stimulus 3/566 71/18722 0.363547774916504 0.580479894563327 CYBA/COL4A1/HNRNPD 3 GO:0000413 protein peptidyl-prolyl isomerization 2/566 42/18722 0.363980335814298 0.580479894563327 PPIA/PPIH 2 GO:0016601 Rac protein signal transduction 2/566 42/18722 0.363980335814298 0.580479894563327 GABARAP/AIF1 2 GO:0021795 cerebral cortex cell migration 2/566 42/18722 0.363980335814298 0.580479894563327 ADGRG1/LAMB1 2 GO:0021879 forebrain neuron differentiation 2/566 42/18722 0.363980335814298 0.580479894563327 B2M/NRP1 2 GO:0030574 collagen catabolic process 2/566 42/18722 0.363980335814298 0.580479894563327 ITGB1/CTSB 2 GO:0030808 regulation of nucleotide biosynthetic process 2/566 42/18722 0.363980335814298 0.580479894563327 ENO1/TMSB4X 2 GO:0032689 negative regulation of interferon-gamma production 2/566 42/18722 0.363980335814298 0.580479894563327 HMGB1/HLA-DRB1 2 GO:0032691 negative regulation of interleukin-1 beta production 2/566 42/18722 0.363980335814298 0.580479894563327 GSTP1/SERPINB1 2 GO:0032965 regulation of collagen biosynthetic process 2/566 42/18722 0.363980335814298 0.580479894563327 VIM/ENG 2 GO:0051452 intracellular pH reduction 2/566 42/18722 0.363980335814298 0.580479894563327 GRN/RAB38 2 GO:2000404 regulation of T cell migration 2/566 42/18722 0.363980335814298 0.580479894563327 APP/AIF1 2 GO:0006576 cellular biogenic amine metabolic process 4/566 101/18722 0.364914491614053 0.580479894563327 AOC1/OAZ1/SMS/PARK7 4 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 7/566 193/18722 0.366583865224037 0.580479894563327 CD74/MIF/IL6ST/ISL1/NRP1/IGF2/IQGAP1 7 GO:0016055 Wnt signaling pathway 15/566 444/18722 0.366919618871382 0.580479894563327 APOE/LRP1/EGFR/ISL1/LGR5/PPP1CA/CCNE1/AMFR/APP/PLPP3/LRP5/MACF1/RUVBL1/FOLR1/ZNRF3 15 GO:0002070 epithelial cell maturation 1/566 15/18722 0.369125422515845 0.580479894563327 TYMS 1 GO:0006268 DNA unwinding involved in DNA replication 1/566 15/18722 0.369125422515845 0.580479894563327 RAD51 1 GO:0007000 nucleolus organization 1/566 15/18722 0.369125422515845 0.580479894563327 RPS19 1 GO:0009083 branched-chain amino acid catabolic process 1/566 15/18722 0.369125422515845 0.580479894563327 ECHS1 1 GO:0010763 positive regulation of fibroblast migration 1/566 15/18722 0.369125422515845 0.580479894563327 ITGB1 1 GO:0010889 regulation of sequestering of triglyceride 1/566 15/18722 0.369125422515845 0.580479894563327 PLIN2 1 GO:0010940 positive regulation of necrotic cell death 1/566 15/18722 0.369125422515845 0.580479894563327 BNIP3 1 GO:0014744 positive regulation of muscle adaptation 1/566 15/18722 0.369125422515845 0.580479894563327 AIF1 1 GO:0015697 quaternary ammonium group transport 1/566 15/18722 0.369125422515845 0.580479894563327 SLC38A2 1 GO:0018146 keratan sulfate biosynthetic process 1/566 15/18722 0.369125422515845 0.580479894563327 B3GNT3 1 GO:0023035 CD40 signaling pathway 1/566 15/18722 0.369125422515845 0.580479894563327 ITGB1 1 GO:0032328 alanine transport 1/566 15/18722 0.369125422515845 0.580479894563327 SLC38A2 1 GO:0032725 positive regulation of granulocyte macrophage colony-stimulating factor production 1/566 15/18722 0.369125422515845 0.580479894563327 ISL1 1 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway 1/566 15/18722 0.369125422515845 0.580479894563327 ISL1 1 GO:0033599 regulation of mammary gland epithelial cell proliferation 1/566 15/18722 0.369125422515845 0.580479894563327 GPX1 1 GO:0034384 high-density lipoprotein particle clearance 1/566 15/18722 0.369125422515845 0.580479894563327 APOE 1 GO:0034638 phosphatidylcholine catabolic process 1/566 15/18722 0.369125422515845 0.580479894563327 APOC1 1 GO:0035627 ceramide transport 1/566 15/18722 0.369125422515845 0.580479894563327 PSAP 1 GO:0036124 histone H3-K9 trimethylation 1/566 15/18722 0.369125422515845 0.580479894563327 PIH1D1 1 GO:0042074 cell migration involved in gastrulation 1/566 15/18722 0.369125422515845 0.580479894563327 LRP5 1 GO:0042182 ketone catabolic process 1/566 15/18722 0.369125422515845 0.580479894563327 PARK7 1 GO:0042559 pteridine-containing compound biosynthetic process 1/566 15/18722 0.369125422515845 0.580479894563327 MTHFS 1 GO:0042976 activation of Janus kinase activity 1/566 15/18722 0.369125422515845 0.580479894563327 PRLR 1 GO:0044406 adhesion of symbiont to host 1/566 15/18722 0.369125422515845 0.580479894563327 HSP90AB1 1 GO:0045064 T-helper 2 cell differentiation 1/566 15/18722 0.369125422515845 0.580479894563327 ANXA1 1 GO:0045725 positive regulation of glycogen biosynthetic process 1/566 15/18722 0.369125422515845 0.580479894563327 IGF2 1 GO:0045842 positive regulation of mitotic metaphase/anaphase transition 1/566 15/18722 0.369125422515845 0.580479894563327 ANAPC11 1 GO:0046184 aldehyde biosynthetic process 1/566 15/18722 0.369125422515845 0.580479894563327 TPI1 1 GO:0050746 regulation of lipoprotein metabolic process 1/566 15/18722 0.369125422515845 0.580479894563327 ITGAV 1 GO:0051127 positive regulation of actin nucleation 1/566 15/18722 0.369125422515845 0.580479894563327 SCIN 1 GO:0051299 centrosome separation 1/566 15/18722 0.369125422515845 0.580479894563327 RANBP1 1 GO:0051938 L-glutamate import 1/566 15/18722 0.369125422515845 0.580479894563327 ITGB1 1 GO:0055091 phospholipid homeostasis 1/566 15/18722 0.369125422515845 0.580479894563327 ABCA1 1 GO:0060046 regulation of acrosome reaction 1/566 15/18722 0.369125422515845 0.580479894563327 B4GALT1 1 GO:0060413 atrial septum morphogenesis 1/566 15/18722 0.369125422515845 0.580479894563327 ISL1 1 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade 1/566 15/18722 0.369125422515845 0.580479894563327 ATP2B4 1 GO:0071025 RNA surveillance 1/566 15/18722 0.369125422515845 0.580479894563327 EXOSC9 1 GO:0071380 cellular response to prostaglandin E stimulus 1/566 15/18722 0.369125422515845 0.580479894563327 P2RY6 1 GO:0071871 response to epinephrine 1/566 15/18722 0.369125422515845 0.580479894563327 ATP2B4 1 GO:0090594 inflammatory response to wounding 1/566 15/18722 0.369125422515845 0.580479894563327 GRN 1 GO:0098712 L-glutamate import across plasma membrane 1/566 15/18722 0.369125422515845 0.580479894563327 ITGB1 1 GO:0106057 negative regulation of calcineurin-mediated signaling 1/566 15/18722 0.369125422515845 0.580479894563327 ATP2B4 1 GO:0150011 regulation of neuron projection arborization 1/566 15/18722 0.369125422515845 0.580479894563327 MACF1 1 GO:1900029 positive regulation of ruffle assembly 1/566 15/18722 0.369125422515845 0.580479894563327 PFN1 1 GO:1901970 positive regulation of mitotic sister chromatid separation 1/566 15/18722 0.369125422515845 0.580479894563327 ANAPC11 1 GO:2000104 negative regulation of DNA-dependent DNA replication 1/566 15/18722 0.369125422515845 0.580479894563327 GMNN 1 GO:0045667 regulation of osteoblast differentiation 5/566 132/18722 0.369254056918989 0.580479894563327 FBN2/CRIM1/IL6ST/LRP5/ATP6AP1 5 GO:0072175 epithelial tube formation 5/566 132/18722 0.369254056918989 0.580479894563327 PFN1/LRP2/SPINT1/PLXNB2/FOLR1 5 GO:0090596 sensory organ morphogenesis 9/566 256/18722 0.370263703199118 0.581861633124769 FBN2/FBN1/HMGN1/RPL38/TENM3/EFEMP1/TUG1/LRP5/NAGLU 9 GO:0006633 fatty acid biosynthetic process 6/566 163/18722 0.371079397233374 0.582663709704538 CD74/MIF/APOC1/ANXA1/GSTP1/PTGES3 6 GO:1902749 regulation of cell cycle G2/M phase transition 4/566 102/18722 0.371805994118457 0.582663709704538 NPM1/CCNB1/CDK1/APP 4 GO:1990542 mitochondrial transmembrane transport 4/566 102/18722 0.371805994118457 0.582663709704538 VDAC1/SLC25A5/HSPD1/STOML2 4 GO:0001707 mesoderm formation 3/566 72/18722 0.371821113942181 0.582663709704538 ITGB1/ITGB4/GJA1 3 GO:0014743 regulation of muscle hypertrophy 3/566 72/18722 0.371821113942181 0.582663709704538 ATP2B4/IL6ST/GLRX3 3 GO:0055021 regulation of cardiac muscle tissue growth 3/566 72/18722 0.371821113942181 0.582663709704538 CCNB1/CDK1/GJA1 3 GO:0070227 lymphocyte apoptotic process 3/566 72/18722 0.371821113942181 0.582663709704538 RPS6/CD74/SLC39A10 3 GO:0071479 cellular response to ionizing radiation 3/566 72/18722 0.371821113942181 0.582663709704538 RPL26/CYBA/RAD51 3 GO:0198738 cell-cell signaling by wnt 15/566 446/18722 0.373426397643528 0.58497337167804 APOE/LRP1/EGFR/ISL1/LGR5/PPP1CA/CCNE1/AMFR/APP/PLPP3/LRP5/MACF1/RUVBL1/FOLR1/ZNRF3 15 GO:0016266 O-glycan processing 2/566 43/18722 0.374897971144391 0.586453186062836 GALNT11/B3GNT3 2 GO:0021983 pituitary gland development 2/566 43/18722 0.374897971144391 0.586453186062836 CDH1/ISL1 2 GO:0046636 negative regulation of alpha-beta T cell activation 2/566 43/18722 0.374897971144391 0.586453186062836 HMGB1/ANXA1 2 GO:0098815 modulation of excitatory postsynaptic potential 2/566 43/18722 0.374897971144391 0.586453186062836 EIF4A3/APP 2 GO:0006997 nucleus organization 5/566 133/18722 0.37527293620863 0.586627497191299 HMGB2/CDK1/RPS19/CHMP5/VRK1 5 GO:0010565 regulation of cellular ketone metabolic process 5/566 133/18722 0.37527293620863 0.586627497191299 CD74/APOC1/ANXA1/ATP2B4/PARK7 5 GO:0014706 striated muscle tissue development 13/566 384/18722 0.378208862684557 0.59081522149318 LRP2/YBX3/CCNB1/ISL1/CACYBP/CDK1/GPX1/ITGB1/ENG/IGF2/GJA1/DSG2/CALR 13 GO:0009166 nucleotide catabolic process 3/566 73/18722 0.380073945480239 0.59081522149318 DUT/DNPH1/NUDT15 3 GO:0051865 protein autoubiquitination 3/566 73/18722 0.380073945480239 0.59081522149318 UBE2T/UBE2D2/AMFR 3 GO:0061035 regulation of cartilage development 3/566 73/18722 0.380073945480239 0.59081522149318 EFEMP1/SCIN/GLG1 3 GO:0032147 activation of protein kinase activity 5/566 134/18722 0.381291170433954 0.59081522149318 HMGB1/PPIA/PARK7/TXN/PRLR 5 GO:0022408 negative regulation of cell-cell adhesion 7/566 196/18722 0.381432775801977 0.59081522149318 CD74/HMGB1/HLA-DRB1/ANXA1/CDH1/SERPINE2/GPNMB 7 GO:0045664 regulation of neuron differentiation 7/566 196/18722 0.381432775801977 0.59081522149318 ISL1/SLC6A4/B2M/TUG1/APP/ZFHX3/CALR 7 GO:0046661 male sex differentiation 6/566 165/18722 0.381897477523787 0.59081522149318 LRP2/HMGB2/YBX3/ADGRG1/EIF2S2/MEA1 6 GO:0014896 muscle hypertrophy 4/566 104/18722 0.385570548727355 0.59081522149318 ATP2B4/IL6ST/CYBA/GLRX3 4 GO:1903076 regulation of protein localization to plasma membrane 4/566 104/18722 0.385570548727355 0.59081522149318 ATP2B4/LRP1/EGFR/ITGB1 4 GO:0002066 columnar/cuboidal epithelial cell development 2/566 44/18722 0.385738050597251 0.59081522149318 IL6ST/TYMS 2 GO:0006775 fat-soluble vitamin metabolic process 2/566 44/18722 0.385738050597251 0.59081522149318 LRP2/LGMN 2 GO:0007528 neuromuscular junction development 2/566 44/18722 0.385738050597251 0.59081522149318 COL4A1/APP 2 GO:0008542 visual learning 2/566 44/18722 0.385738050597251 0.59081522149318 ITGB1/APP 2 GO:0030521 androgen receptor signaling pathway 2/566 44/18722 0.385738050597251 0.59081522149318 DNAJA1/PARK7 2 GO:0031295 T cell costimulation 2/566 44/18722 0.385738050597251 0.59081522149318 LGALS1/DPP4 2 GO:0042269 regulation of natural killer cell mediated cytotoxicity 2/566 44/18722 0.385738050597251 0.59081522149318 HLA-B/HLA-A 2 GO:0062208 positive regulation of pattern recognition receptor signaling pathway 2/566 44/18722 0.385738050597251 0.59081522149318 HMGB1/CYBA 2 GO:0097178 ruffle assembly 2/566 44/18722 0.385738050597251 0.59081522149318 PFN1/AIF1 2 GO:0150076 neuroinflammatory response 2/566 44/18722 0.385738050597251 0.59081522149318 ITGB1/GRN 2 GO:1903573 negative regulation of response to endoplasmic reticulum stress 2/566 44/18722 0.385738050597251 0.59081522149318 PARK7/UBXN1 2 GO:0001991 regulation of systemic arterial blood pressure by circulatory renin-angiotensin 1/566 16/18722 0.388213197725981 0.59081522149318 MME 1 GO:0002713 negative regulation of B cell mediated immunity 1/566 16/18722 0.388213197725981 0.59081522149318 CD46 1 GO:0002830 positive regulation of type 2 immune response 1/566 16/18722 0.388213197725981 0.59081522149318 CD74 1 GO:0002890 negative regulation of immunoglobulin mediated immune response 1/566 16/18722 0.388213197725981 0.59081522149318 CD46 1 GO:0002921 negative regulation of humoral immune response 1/566 16/18722 0.388213197725981 0.59081522149318 CD46 1 GO:0003084 positive regulation of systemic arterial blood pressure 1/566 16/18722 0.388213197725981 0.59081522149318 CYBA 1 GO:0003198 epithelial to mesenchymal transition involved in endocardial cushion formation 1/566 16/18722 0.388213197725981 0.59081522149318 ENG 1 GO:0006349 regulation of gene expression by genetic imprinting 1/566 16/18722 0.388213197725981 0.59081522149318 IGF2 1 GO:0006544 glycine metabolic process 1/566 16/18722 0.388213197725981 0.59081522149318 GCSH 1 GO:0006555 methionine metabolic process 1/566 16/18722 0.388213197725981 0.59081522149318 SMS 1 GO:0006857 oligopeptide transport 1/566 16/18722 0.388213197725981 0.59081522149318 GJA1 1 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 1/566 16/18722 0.388213197725981 0.59081522149318 RPL26 1 GO:0009048 dosage compensation by inactivation of X chromosome 1/566 16/18722 0.388213197725981 0.59081522149318 XIST 1 GO:0009111 vitamin catabolic process 1/566 16/18722 0.388213197725981 0.59081522149318 MTHFS 1 GO:0010225 response to UV-C 1/566 16/18722 0.388213197725981 0.59081522149318 HMGN1 1 GO:0010919 regulation of inositol phosphate biosynthetic process 1/566 16/18722 0.388213197725981 0.59081522149318 P2RY6 1 GO:0014819 regulation of skeletal muscle contraction 1/566 16/18722 0.388213197725981 0.59081522149318 GSTO1 1 GO:0019081 viral translation 1/566 16/18722 0.388213197725981 0.59081522149318 SSB 1 GO:0021535 cell migration in hindbrain 1/566 16/18722 0.388213197725981 0.59081522149318 ITGB1 1 GO:0030540 female genitalia development 1/566 16/18722 0.388213197725981 0.59081522149318 LRP2 1 GO:0031268 pseudopodium organization 1/566 16/18722 0.388213197725981 0.59081522149318 RAB25 1 GO:0034138 toll-like receptor 3 signaling pathway 1/566 16/18722 0.388213197725981 0.59081522149318 COLEC12 1 GO:0034374 low-density lipoprotein particle remodeling 1/566 16/18722 0.388213197725981 0.59081522149318 APOE 1 GO:0035067 negative regulation of histone acetylation 1/566 16/18722 0.388213197725981 0.59081522149318 PIH1D1 1 GO:0035751 regulation of lysosomal lumen pH 1/566 16/18722 0.388213197725981 0.59081522149318 GRN 1 GO:0048385 regulation of retinoic acid receptor signaling pathway 1/566 16/18722 0.388213197725981 0.59081522149318 CALR 1 GO:0050862 positive regulation of T cell receptor signaling pathway 1/566 16/18722 0.388213197725981 0.59081522149318 RPS3 1 GO:0050884 neuromuscular process controlling posture 1/566 16/18722 0.388213197725981 0.59081522149318 GAA 1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis 1/566 16/18722 0.388213197725981 0.59081522149318 APOE 1 GO:0055089 fatty acid homeostasis 1/566 16/18722 0.388213197725981 0.59081522149318 APOE 1 GO:0060330 regulation of response to interferon-gamma 1/566 16/18722 0.388213197725981 0.59081522149318 HSP90AB1 1 GO:0060334 regulation of interferon-gamma-mediated signaling pathway 1/566 16/18722 0.388213197725981 0.59081522149318 HSP90AB1 1 GO:0061684 chaperone-mediated autophagy 1/566 16/18722 0.388213197725981 0.59081522149318 EEF1A1 1 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process 1/566 16/18722 0.388213197725981 0.59081522149318 TPRKB 1 GO:0070571 negative regulation of neuron projection regeneration 1/566 16/18722 0.388213197725981 0.59081522149318 SPP1 1 GO:0071639 positive regulation of monocyte chemotactic protein-1 production 1/566 16/18722 0.388213197725981 0.59081522149318 HMGB1 1 GO:0072148 epithelial cell fate commitment 1/566 16/18722 0.388213197725981 0.59081522149318 NRP1 1 GO:0097202 activation of cysteine-type endopeptidase activity 1/566 16/18722 0.388213197725981 0.59081522149318 LGMN 1 GO:0097428 protein maturation by iron-sulfur cluster transfer 1/566 16/18722 0.388213197725981 0.59081522149318 GLRX3 1 GO:0098969 neurotransmitter receptor transport to postsynaptic membrane 1/566 16/18722 0.388213197725981 0.59081522149318 CLSTN1 1 GO:0099010 modification of postsynaptic structure 1/566 16/18722 0.388213197725981 0.59081522149318 PFN1 1 GO:0099116 tRNA 5'-end processing 1/566 16/18722 0.388213197725981 0.59081522149318 SSB 1 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration 1/566 16/18722 0.388213197725981 0.59081522149318 ATP2B1 1 GO:0099633 protein localization to postsynaptic specialization membrane 1/566 16/18722 0.388213197725981 0.59081522149318 DAG1 1 GO:0099645 neurotransmitter receptor localization to postsynaptic specialization membrane 1/566 16/18722 0.388213197725981 0.59081522149318 DAG1 1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway 1/566 16/18722 0.388213197725981 0.59081522149318 SEMA6A 1 GO:1901201 regulation of extracellular matrix assembly 1/566 16/18722 0.388213197725981 0.59081522149318 DAG1 1 GO:1902101 positive regulation of metaphase/anaphase transition of cell cycle 1/566 16/18722 0.388213197725981 0.59081522149318 ANAPC11 1 GO:1902931 negative regulation of alcohol biosynthetic process 1/566 16/18722 0.388213197725981 0.59081522149318 APOE 1 GO:1904683 regulation of metalloendopeptidase activity 1/566 16/18722 0.388213197725981 0.59081522149318 TIMP3 1 GO:1904862 inhibitory synapse assembly 1/566 16/18722 0.388213197725981 0.59081522149318 PLXNB1 1 GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway 1/566 16/18722 0.388213197725981 0.59081522149318 ZNRF3 1 GO:2000232 regulation of rRNA processing 1/566 16/18722 0.388213197725981 0.59081522149318 TRMT112 1 GO:2000651 positive regulation of sodium ion transmembrane transporter activity 1/566 16/18722 0.388213197725981 0.59081522149318 GLRX 1 GO:2001224 positive regulation of neuron migration 1/566 16/18722 0.388213197725981 0.59081522149318 SEMA6A 1 GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway 3/566 74/18722 0.388303085824134 0.59081522149318 ISL1/PARK7/CALR 3 GO:0048332 mesoderm morphogenesis 3/566 74/18722 0.388303085824134 0.59081522149318 ITGB1/ITGB4/GJA1 3 GO:0071356 cellular response to tumor necrosis factor 8/566 229/18722 0.389536418245624 0.592489283918524 RPS3/YBX3/CYBA/GSTP1/KRT8/TMSB4X/KRT18/ASAH1 8 GO:0048167 regulation of synaptic plasticity 7/566 198/18722 0.391344610316703 0.595036272243839 APOE/TYROBP/SERPINE2/LGMN/CDC20/APP/MME 7 GO:0003158 endothelium development 5/566 136/18722 0.393320117416718 0.597744761041733 FSTL1/GPX1/MET/NRP1/GJA1 5 GO:0001822 kidney development 10/566 293/18722 0.393394463129442 0.597744761041733 FBN1/LRP2/LAMA5/ADAMTS6/HPGD/NRP1/SERPINF1/IQGAP1/MME/SEC61A1 10 GO:0003009 skeletal muscle contraction 2/566 45/18722 0.396495286152576 0.600218408315008 GSTO1/GAA 2 GO:0003197 endocardial cushion development 2/566 45/18722 0.396495286152576 0.600218408315008 ISL1/ENG 2 GO:0010824 regulation of centrosome duplication 2/566 45/18722 0.396495286152576 0.600218408315008 NPM1/CHMP5 2 GO:0031670 cellular response to nutrient 2/566 45/18722 0.396495286152576 0.600218408315008 ATP2B1/FOLR1 2 GO:0045933 positive regulation of muscle contraction 2/566 45/18722 0.396495286152576 0.600218408315008 ENO1/GSTO1 2 GO:0060421 positive regulation of heart growth 2/566 45/18722 0.396495286152576 0.600218408315008 CCNB1/CDK1 2 GO:1901985 positive regulation of protein acetylation 2/566 45/18722 0.396495286152576 0.600218408315008 ISL1/PIH1D1 2 GO:0036465 synaptic vesicle recycling 3/566 75/18722 0.396505466948436 0.600218408315008 CALM1/ACTG1/CANX 3 GO:0043627 response to estrogen 3/566 75/18722 0.396505466948436 0.600218408315008 LDHA/KRT19/HSPD1 3 GO:0048662 negative regulation of smooth muscle cell proliferation 3/566 75/18722 0.396505466948436 0.600218408315008 APOE/GSTP1/AIF1 3 GO:0061333 renal tubule morphogenesis 3/566 75/18722 0.396505466948436 0.600218408315008 LAMA5/COL4A1/LGR5 3 GO:0000086 G2/M transition of mitotic cell cycle 5/566 137/18722 0.399328093366763 0.60387522814838 CALM1/CCNB1/CDK1/CCNA2/APP 5 GO:0030879 mammary gland development 5/566 137/18722 0.399328093366763 0.60387522814838 NME1/GPX1/UMPS/LRP5/PRLR 5 GO:0055123 digestive system development 5/566 137/18722 0.399328093366763 0.60387522814838 IL6ST/TYMS/CCNB1/EGFR/IGF2 5 GO:0007517 muscle organ development 11/566 327/18722 0.402280023653402 0.605039251316778 LRP2/LAMA5/YBX3/ISL1/GPX1/ENG/DAG1/FRG1/IGF2/SRI/ZFHX3 11 GO:0014855 striated muscle cell proliferation 3/566 76/18722 0.404678135304425 0.605039251316778 CCNB1/CDK1/GJA1 3 GO:0021536 diencephalon development 3/566 76/18722 0.404678135304425 0.605039251316778 CDH1/ISL1/NRP1 3 GO:0050730 regulation of peptidyl-tyrosine phosphorylation 9/566 264/18722 0.404724907089605 0.605039251316778 CD74/MIF/IL6ST/EGFR/ISL1/NRP1/APP/IGF2/IQGAP1 9 GO:0000724 double-strand break repair via homologous recombination 5/566 138/18722 0.405329951489769 0.605039251316778 UBE2N/RPA3/RAD51/PPP4C/PSMD14 5 GO:0048193 Golgi vesicle transport 10/566 296/18722 0.405616916999163 0.605039251316778 SNX2/ARF5/TFG/COPZ1/LMAN1/KRT18/NRBP1/PLPP3/MACF1/VPS13C 10 GO:0000018 regulation of DNA recombination 4/566 107/18722 0.406141485436792 0.605039251316778 ALYREF/RAD51/PPP4C/TFRC 4 GO:0031532 actin cytoskeleton reorganization 4/566 107/18722 0.406141485436792 0.605039251316778 ANXA1/PHPT1/NRP1/THSD7A 4 GO:0032526 response to retinoic acid 4/566 107/18722 0.406141485436792 0.605039251316778 SLC6A4/ABCA1/SERPINF1/GJA1 4 GO:0042303 molting cycle 4/566 107/18722 0.406141485436792 0.605039251316778 LAMA5/SNRPE/EGFR/LGR5 4 GO:0042633 hair cycle 4/566 107/18722 0.406141485436792 0.605039251316778 LAMA5/SNRPE/EGFR/LGR5 4 GO:0006474 N-terminal protein amino acid acetylation 1/566 17/18722 0.406724441716525 0.605039251316778 NAA20 1 GO:0006895 Golgi to endosome transport 1/566 17/18722 0.406724441716525 0.605039251316778 VPS13C 1 GO:0006901 vesicle coating 1/566 17/18722 0.406724441716525 0.605039251316778 TFG 1 GO:0008334 histone mRNA metabolic process 1/566 17/18722 0.406724441716525 0.605039251316778 SSB 1 GO:0010470 regulation of gastrulation 1/566 17/18722 0.406724441716525 0.605039251316778 DAG1 1 GO:0010612 regulation of cardiac muscle adaptation 1/566 17/18722 0.406724441716525 0.605039251316778 ATP2B4 1 GO:0010934 macrophage cytokine production 1/566 17/18722 0.406724441716525 0.605039251316778 CD74 1 GO:0010935 regulation of macrophage cytokine production 1/566 17/18722 0.406724441716525 0.605039251316778 CD74 1 GO:0016264 gap junction assembly 1/566 17/18722 0.406724441716525 0.605039251316778 GJA1 1 GO:0032048 cardiolipin metabolic process 1/566 17/18722 0.406724441716525 0.605039251316778 STOML2 1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway 1/566 17/18722 0.406724441716525 0.605039251316778 CHMP5 1 GO:0032604 granulocyte macrophage colony-stimulating factor production 1/566 17/18722 0.406724441716525 0.605039251316778 ISL1 1 GO:0032645 regulation of granulocyte macrophage colony-stimulating factor production 1/566 17/18722 0.406724441716525 0.605039251316778 ISL1 1 GO:0042053 regulation of dopamine metabolic process 1/566 17/18722 0.406724441716525 0.605039251316778 PARK7 1 GO:0042069 regulation of catecholamine metabolic process 1/566 17/18722 0.406724441716525 0.605039251316778 PARK7 1 GO:0042772 DNA damage response, signal transduction resulting in transcription 1/566 17/18722 0.406724441716525 0.605039251316778 RPL26 1 GO:0042953 lipoprotein transport 1/566 17/18722 0.406724441716525 0.605039251316778 LRP1 1 GO:0043117 positive regulation of vascular permeability 1/566 17/18722 0.406724441716525 0.605039251316778 APOE 1 GO:0043649 dicarboxylic acid catabolic process 1/566 17/18722 0.406724441716525 0.605039251316778 MTHFS 1 GO:0045815 positive regulation of gene expression, epigenetic 1/566 17/18722 0.406724441716525 0.605039251316778 CDCA4 1 GO:0046855 inositol phosphate dephosphorylation 1/566 17/18722 0.406724441716525 0.605039251316778 IMPA2 1 GO:0051580 regulation of neurotransmitter uptake 1/566 17/18722 0.406724441716525 0.605039251316778 ITGB1 1 GO:0061158 3'-UTR-mediated mRNA destabilization 1/566 17/18722 0.406724441716525 0.605039251316778 HNRNPD 1 GO:0061952 midbody abscission 1/566 17/18722 0.406724441716525 0.605039251316778 CHMP5 1 GO:0070293 renal absorption 1/566 17/18722 0.406724441716525 0.605039251316778 HBB 1 GO:0071371 cellular response to gonadotropin stimulus 1/566 17/18722 0.406724441716525 0.605039251316778 CCNA2 1 GO:0071816 tail-anchored membrane protein insertion into ER membrane 1/566 17/18722 0.406724441716525 0.605039251316778 EMC1 1 GO:0072673 lamellipodium morphogenesis 1/566 17/18722 0.406724441716525 0.605039251316778 SNX2 1 GO:0090494 dopamine uptake 1/566 17/18722 0.406724441716525 0.605039251316778 PARK7 1 GO:0097067 cellular response to thyroid hormone stimulus 1/566 17/18722 0.406724441716525 0.605039251316778 CTSB 1 GO:0098962 regulation of postsynaptic neurotransmitter receptor activity 1/566 17/18722 0.406724441716525 0.605039251316778 AKAP9 1 GO:1901569 fatty acid derivative catabolic process 1/566 17/18722 0.406724441716525 0.605039251316778 HPGD 1 GO:1903242 regulation of cardiac muscle hypertrophy in response to stress 1/566 17/18722 0.406724441716525 0.605039251316778 ATP2B4 1 GO:1903540 establishment of protein localization to postsynaptic membrane 1/566 17/18722 0.406724441716525 0.605039251316778 CLSTN1 1 GO:2000811 negative regulation of anoikis 1/566 17/18722 0.406724441716525 0.605039251316778 ITGB1 1 GO:0006195 purine nucleotide catabolic process 2/566 46/18722 0.407164779188021 0.605039251316778 DNPH1/NUDT15 2 GO:0006984 ER-nucleus signaling pathway 2/566 46/18722 0.407164779188021 0.605039251316778 AMFR/EIF2A 2 GO:0031294 lymphocyte costimulation 2/566 46/18722 0.407164779188021 0.605039251316778 LGALS1/DPP4 2 GO:0042398 cellular modified amino acid biosynthetic process 2/566 46/18722 0.407164779188021 0.605039251316778 PARK7/MTHFS 2 GO:0043462 regulation of ATPase activity 2/566 46/18722 0.407164779188021 0.605039251316778 PFN1/DNAJC9 2 GO:2000107 negative regulation of leukocyte apoptotic process 2/566 46/18722 0.407164779188021 0.605039251316778 CD74/SLC39A10 2 GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 8/566 233/18722 0.407944875573094 0.605996191542014 ATP2B4/PSAP/LGR5/ADGRG1/ABCA1/GNAI3/NME2/ADRB1 8 GO:0030216 keratinocyte differentiation 5/566 139/18722 0.411324381570542 0.610812590644448 ANXA1/KRT10/NME2/ASAH1/TXNIP 5 GO:0048644 muscle organ morphogenesis 3/566 77/18722 0.41281825049686 0.612622283737341 LRP2/ISL1/ENG 3 GO:1901983 regulation of protein acetylation 3/566 77/18722 0.41281825049686 0.612622283737341 ISL1/PARK7/PIH1D1 3 GO:0022037 metencephalon development 4/566 108/18722 0.412970613134606 0.6126441751667 SERPINE2/HNRNPD/AIF1/NAGLU 4 GO:0000725 recombinational repair 5/566 140/18722 0.417310097320017 0.616653603511903 UBE2N/RPA3/RAD51/PPP4C/PSMD14 5 GO:0046165 alcohol biosynthetic process 5/566 140/18722 0.417310097320017 0.616653603511903 APOE/PARK7/IMPA2/ASAH1/P2RY6 5 GO:0001754 eye photoreceptor cell differentiation 2/566 47/18722 0.417742001840346 0.616653603511903 TUG1/NAGLU 2 GO:0010799 regulation of peptidyl-threonine phosphorylation 2/566 47/18722 0.417742001840346 0.616653603511903 CALM1/APP 2 GO:0016073 snRNA metabolic process 2/566 47/18722 0.417742001840346 0.616653603511903 NHP2/EXOSC9 2 GO:0016574 histone ubiquitination 2/566 47/18722 0.417742001840346 0.616653603511903 UBE2N/PARK7 2 GO:0032369 negative regulation of lipid transport 2/566 47/18722 0.417742001840346 0.616653603511903 APOC1/ITGAV 2 GO:0045332 phospholipid translocation 2/566 47/18722 0.417742001840346 0.616653603511903 ATP10D/ABCA1 2 GO:0045747 positive regulation of Notch signaling pathway 2/566 47/18722 0.417742001840346 0.616653603511903 IL6ST/PDCD10 2 GO:0046677 response to antibiotic 2/566 47/18722 0.417742001840346 0.616653603511903 RPL23/AOC1 2 GO:0097300 programmed necrotic cell death 2/566 47/18722 0.417742001840346 0.616653603511903 YBX3/ASAH1 2 GO:0007219 Notch signaling pathway 6/566 172/18722 0.419729853422844 0.616653603511903 KRT19/IL6ST/PDCD10/CD46/APP/GALNT11 6 GO:0032410 negative regulation of transporter activity 4/566 109/18722 0.419782780436075 0.616653603511903 CALM1/C4orf3/GSTO1/SRI 4 GO:0009064 glutamine family amino acid metabolic process 3/566 78/18722 0.420923083852749 0.616653603511903 ATP2B4/MTHFS/GMPS 3 GO:0030500 regulation of bone mineralization 3/566 78/18722 0.420923083852749 0.616653603511903 FBN2/SRGN/ATP2B1 3 GO:0090049 regulation of cell migration involved in sprouting angiogenesis 3/566 78/18722 0.420923083852749 0.616653603511903 ANXA1/NRP1/PDCD10 3 GO:0090559 regulation of membrane permeability 3/566 78/18722 0.420923083852749 0.616653603511903 VDAC2/SLC25A5/BNIP3 3 GO:1901616 organic hydroxy compound catabolic process 3/566 78/18722 0.420923083852749 0.616653603511903 APOE/TPI1/IMPA2 3 GO:0046395 carboxylic acid catabolic process 8/566 236/18722 0.421746609226364 0.616653603511903 ATP2B4/ETFB/GCSH/ACAT2/MTHFS/ECHS1/ECH1/SLC27A2 8 GO:1903038 negative regulation of leukocyte cell-cell adhesion 5/566 141/18722 0.42328583668709 0.616653603511903 CD74/HMGB1/HLA-DRB1/ANXA1/GPNMB 5 GO:0001522 pseudouridine synthesis 1/566 18/18722 0.424676538267631 0.616653603511903 NHP2 1 GO:0002076 osteoblast development 1/566 18/18722 0.424676538267631 0.616653603511903 LRP5 1 GO:0002223 stimulatory C-type lectin receptor signaling pathway 1/566 18/18722 0.424676538267631 0.616653603511903 TYROBP 1 GO:0002544 chronic inflammatory response 1/566 18/18722 0.424676538267631 0.616653603511903 GJA1 1 GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 1/566 18/18722 0.424676538267631 0.616653603511903 CD46 1 GO:0006337 nucleosome disassembly 1/566 18/18722 0.424676538267631 0.616653603511903 SUPT16H 1 GO:0007549 dosage compensation 1/566 18/18722 0.424676538267631 0.616653603511903 XIST 1 GO:0009125 nucleoside monophosphate catabolic process 1/566 18/18722 0.424676538267631 0.616653603511903 DNPH1 1 GO:0010663 positive regulation of striated muscle cell apoptotic process 1/566 18/18722 0.424676538267631 0.616653603511903 BNIP3 1 GO:0010666 positive regulation of cardiac muscle cell apoptotic process 1/566 18/18722 0.424676538267631 0.616653603511903 BNIP3 1 GO:0010985 negative regulation of lipoprotein particle clearance 1/566 18/18722 0.424676538267631 0.616653603511903 APOC1 1 GO:0030206 chondroitin sulfate biosynthetic process 1/566 18/18722 0.424676538267631 0.616653603511903 CHPF 1 GO:0030728 ovulation 1/566 18/18722 0.424676538267631 0.616653603511903 HPGD 1 GO:0030730 sequestering of triglyceride 1/566 18/18722 0.424676538267631 0.616653603511903 PLIN2 1 GO:0031643 positive regulation of myelination 1/566 18/18722 0.424676538267631 0.616653603511903 DAG1 1 GO:0031649 heat generation 1/566 18/18722 0.424676538267631 0.616653603511903 ADRB1 1 GO:0032769 negative regulation of monooxygenase activity 1/566 18/18722 0.424676538267631 0.616653603511903 ATP2B4 1 GO:0033189 response to vitamin A 1/566 18/18722 0.424676538267631 0.616653603511903 TYMS 1 GO:0034162 toll-like receptor 9 signaling pathway 1/566 18/18722 0.424676538267631 0.616653603511903 HMGB1 1 GO:0042136 neurotransmitter biosynthetic process 1/566 18/18722 0.424676538267631 0.616653603511903 SLC6A4 1 GO:0044872 lipoprotein localization 1/566 18/18722 0.424676538267631 0.616653603511903 LRP1 1 GO:0045187 regulation of circadian sleep/wake cycle, sleep 1/566 18/18722 0.424676538267631 0.616653603511903 ADRB1 1 GO:0045623 negative regulation of T-helper cell differentiation 1/566 18/18722 0.424676538267631 0.616653603511903 ANXA1 1 GO:0046838 phosphorylated carbohydrate dephosphorylation 1/566 18/18722 0.424676538267631 0.616653603511903 IMPA2 1 GO:0048643 positive regulation of skeletal muscle tissue development 1/566 18/18722 0.424676538267631 0.616653603511903 IGF2 1 GO:0050665 hydrogen peroxide biosynthetic process 1/566 18/18722 0.424676538267631 0.616653603511903 CYBA 1 GO:0051782 negative regulation of cell division 1/566 18/18722 0.424676538267631 0.616653603511903 TXNIP 1 GO:0051895 negative regulation of focal adhesion assembly 1/566 18/18722 0.424676538267631 0.616653603511903 LRP1 1 GO:0060546 negative regulation of necroptotic process 1/566 18/18722 0.424676538267631 0.616653603511903 YBX3 1 GO:0071071 regulation of phospholipid biosynthetic process 1/566 18/18722 0.424676538267631 0.616653603511903 RAB38 1 GO:0071318 cellular response to ATP 1/566 18/18722 0.424676538267631 0.616653603511903 HSP90B1 1 GO:0071360 cellular response to exogenous dsRNA 1/566 18/18722 0.424676538267631 0.616653603511903 COLEC12 1 GO:0090493 catecholamine uptake 1/566 18/18722 0.424676538267631 0.616653603511903 PARK7 1 GO:0098877 neurotransmitter receptor transport to plasma membrane 1/566 18/18722 0.424676538267631 0.616653603511903 CLSTN1 1 GO:0150079 negative regulation of neuroinflammatory response 1/566 18/18722 0.424676538267631 0.616653603511903 GRN 1 GO:0150118 negative regulation of cell-substrate junction organization 1/566 18/18722 0.424676538267631 0.616653603511903 LRP1 1 GO:1900006 positive regulation of dendrite development 1/566 18/18722 0.424676538267631 0.616653603511903 IQGAP1 1 GO:1900242 regulation of synaptic vesicle endocytosis 1/566 18/18722 0.424676538267631 0.616653603511903 CALM1 1 GO:1901673 regulation of mitotic spindle assembly 1/566 18/18722 0.424676538267631 0.616653603511903 CHMP5 1 GO:1902001 fatty acid transmembrane transport 1/566 18/18722 0.424676538267631 0.616653603511903 SLC2A1 1 GO:1903209 positive regulation of oxidative stress-induced cell death 1/566 18/18722 0.424676538267631 0.616653603511903 PARK7 1 GO:1905820 positive regulation of chromosome separation 1/566 18/18722 0.424676538267631 0.616653603511903 ANAPC11 1 GO:1990840 response to lectin 1/566 18/18722 0.424676538267631 0.616653603511903 TYROBP 1 GO:1990858 cellular response to lectin 1/566 18/18722 0.424676538267631 0.616653603511903 TYROBP 1 GO:2000136 regulation of cell proliferation involved in heart morphogenesis 1/566 18/18722 0.424676538267631 0.616653603511903 ISL1 1 GO:0003014 renal system process 4/566 110/18722 0.426576237374525 0.619008281874637 CYBA/LGMN/HBB/GJA1 4 GO:0048259 regulation of receptor-mediated endocytosis 4/566 110/18722 0.426576237374525 0.619008281874637 APOC1/B2M/ITGAV/SERPINE1 4 GO:0002686 negative regulation of leukocyte migration 2/566 48/18722 0.428222779134384 0.619781473571612 MIF/DPP4 2 GO:0002715 regulation of natural killer cell mediated immunity 2/566 48/18722 0.428222779134384 0.619781473571612 HLA-B/HLA-A 2 GO:0010569 regulation of double-strand break repair via homologous recombination 2/566 48/18722 0.428222779134384 0.619781473571612 RAD51/PPP4C 2 GO:0033628 regulation of cell adhesion mediated by integrin 2/566 48/18722 0.428222779134384 0.619781473571612 DPP4/SERPINE1 2 GO:0042149 cellular response to glucose starvation 2/566 48/18722 0.428222779134384 0.619781473571612 HNRNPA1/SLC2A1 2 GO:0042908 xenobiotic transport 2/566 48/18722 0.428222779134384 0.619781473571612 SLC2A1/GJA1 2 GO:0045005 DNA-dependent DNA replication maintenance of fidelity 2/566 48/18722 0.428222779134384 0.619781473571612 ALYREF/RAD51 2 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 2/566 48/18722 0.428222779134384 0.619781473571612 PPP1CA/TIMP3 2 GO:0060420 regulation of heart growth 3/566 79/18722 0.42899001689231 0.620488484471919 CCNB1/CDK1/GJA1 3 GO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide 3/566 79/18722 0.42899001689231 0.620488484471919 GAPDH/HMGN2/RPS19 3 GO:0016570 histone modification 15/566 463/18722 0.429217622227797 0.620616061759712 MORF4L2/UBE2N/CCNB1/ISL1/CDK1/TRMT112/PARK7/POLE3/HAT1/CCNA2/VRK1/IGF2/RUVBL1/DPY30/PIH1D1 15 GO:0001659 temperature homeostasis 6/566 174/18722 0.4304976637433 0.622264804865316 GPX1/PRLR/FH/GJA1/IGF1R/ADRB1 6 GO:1905475 regulation of protein localization to membrane 6/566 175/18722 0.435869927314137 0.625411001221878 ATP2B4/LRP1/EGFR/ITGB1/DAG1/PDCD5 6 GO:0001570 vasculogenesis 3/566 80/18722 0.437016539711757 0.625411001221878 ITGB8/ITGAV/ENG 3 GO:0009791 post-embryonic development 3/566 80/18722 0.437016539711757 0.625411001221878 FBN1/HMGN1/EFEMP1 3 GO:0021766 hippocampus development 3/566 80/18722 0.437016539711757 0.625411001221878 ATP2B4/NME1/ANXA3 3 GO:0051303 establishment of chromosome localization 3/566 80/18722 0.437016539711757 0.625411001221878 CCNB1/NUDC/CHMP5 3 GO:0071229 cellular response to acid chemical 3/566 80/18722 0.437016539711757 0.625411001221878 CYBA/COL4A1/HNRNPD 3 GO:0120193 tight junction organization 3/566 80/18722 0.437016539711757 0.625411001221878 ACTG1/SVEP1/GJA1 3 GO:0002204 somatic recombination of immunoglobulin genes involved in immune response 2/566 49/18722 0.438603271850576 0.625411001221878 HSPD1/TFRC 2 GO:0002208 somatic diversification of immunoglobulins involved in immune response 2/566 49/18722 0.438603271850576 0.625411001221878 HSPD1/TFRC 2 GO:0008038 neuron recognition 2/566 49/18722 0.438603271850576 0.625411001221878 NRP1/APP 2 GO:0009994 oocyte differentiation 2/566 49/18722 0.438603271850576 0.625411001221878 CCNB1/LGR5 2 GO:0021695 cerebellar cortex development 2/566 49/18722 0.438603271850576 0.625411001221878 SERPINE2/NAGLU 2 GO:0030225 macrophage differentiation 2/566 49/18722 0.438603271850576 0.625411001221878 HLA-DRB1/APP 2 GO:0032692 negative regulation of interleukin-1 production 2/566 49/18722 0.438603271850576 0.625411001221878 GSTP1/SERPINB1 2 GO:0042461 photoreceptor cell development 2/566 49/18722 0.438603271850576 0.625411001221878 TUG1/NAGLU 2 GO:0045190 isotype switching 2/566 49/18722 0.438603271850576 0.625411001221878 HSPD1/TFRC 2 GO:0045778 positive regulation of ossification 2/566 49/18722 0.438603271850576 0.625411001221878 FBN2/ATP2B1 2 GO:0046605 regulation of centrosome cycle 2/566 49/18722 0.438603271850576 0.625411001221878 NPM1/CHMP5 2 GO:0048168 regulation of neuronal synaptic plasticity 2/566 49/18722 0.438603271850576 0.625411001221878 APOE/APP 2 GO:0051445 regulation of meiotic cell cycle 2/566 49/18722 0.438603271850576 0.625411001221878 CDC20/CALR 2 GO:0060964 regulation of gene silencing by miRNA 2/566 49/18722 0.438603271850576 0.625411001221878 NEAT1/EGFR 2 GO:0060986 endocrine hormone secretion 2/566 49/18722 0.438603271850576 0.625411001221878 CGA/GJA1 2 GO:0070169 positive regulation of biomineral tissue development 2/566 49/18722 0.438603271850576 0.625411001221878 FBN2/ATP2B1 2 GO:1904752 regulation of vascular associated smooth muscle cell migration 2/566 49/18722 0.438603271850576 0.625411001221878 LRP1/IQGAP1 2 GO:1990928 response to amino acid starvation 2/566 49/18722 0.438603271850576 0.625411001221878 SLC38A2/EIF2A 2 GO:0001676 long-chain fatty acid metabolic process 4/566 112/18722 0.440100257244142 0.625411001221878 GSTP1/PTGES3/GPX1/SLC27A2 4 GO:0046632 alpha-beta T cell differentiation 4/566 112/18722 0.440100257244142 0.625411001221878 HMGB1/HLA-DRB1/ANXA1/HLA-DRA 4 GO:0016054 organic acid catabolic process 8/566 240/18722 0.440111430058456 0.625411001221878 ATP2B4/ETFB/GCSH/ACAT2/MTHFS/ECHS1/ECH1/SLC27A2 8 GO:0042391 regulation of membrane potential 14/566 434/18722 0.440523084981002 0.625411001221878 CALM1/PRDX3/EIF4A3/PARK7/STOML2/AKAP9/BNIP3/DSC2/APP/GLRX/SRI/GJA1/DSG2/ADRB1 14 GO:0007612 learning 5/566 144/18722 0.441140945246744 0.625411001221878 VDAC1/LGMN/EIF4A3/ITGB1/APP 5 GO:0106106 cold-induced thermogenesis 5/566 144/18722 0.441140945246744 0.625411001221878 PRLR/FH/GJA1/IGF1R/ADRB1 5 GO:0120161 regulation of cold-induced thermogenesis 5/566 144/18722 0.441140945246744 0.625411001221878 PRLR/FH/GJA1/IGF1R/ADRB1 5 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic 1/566 19/18722 0.442086347898754 0.625411001221878 EXOSC9 1 GO:0002888 positive regulation of myeloid leukocyte mediated immunity 1/566 19/18722 0.442086347898754 0.625411001221878 TYROBP 1 GO:0003085 negative regulation of systemic arterial blood pressure 1/566 19/18722 0.442086347898754 0.625411001221878 ADRB1 1 GO:0006071 glycerol metabolic process 1/566 19/18722 0.442086347898754 0.625411001221878 TPI1 1 GO:0006144 purine nucleobase metabolic process 1/566 19/18722 0.442086347898754 0.625411001221878 GMPS 1 GO:0006491 N-glycan processing 1/566 19/18722 0.442086347898754 0.625411001221878 GANAB 1 GO:0009081 branched-chain amino acid metabolic process 1/566 19/18722 0.442086347898754 0.625411001221878 ECHS1 1 GO:0009223 pyrimidine deoxyribonucleotide catabolic process 1/566 19/18722 0.442086347898754 0.625411001221878 DUT 1 GO:0009226 nucleotide-sugar biosynthetic process 1/566 19/18722 0.442086347898754 0.625411001221878 NANS 1 GO:0010002 cardioblast differentiation 1/566 19/18722 0.442086347898754 0.625411001221878 ISL1 1 GO:0010738 regulation of protein kinase A signaling 1/566 19/18722 0.442086347898754 0.625411001221878 MIF 1 GO:0010885 regulation of cholesterol storage 1/566 19/18722 0.442086347898754 0.625411001221878 ABCA1 1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling 1/566 19/18722 0.442086347898754 0.625411001221878 SERPINE2 1 GO:0030011 maintenance of cell polarity 1/566 19/18722 0.442086347898754 0.625411001221878 ARPC5 1 GO:0036498 IRE1-mediated unfolded protein response 1/566 19/18722 0.442086347898754 0.625411001221878 COPS5 1 GO:0042776 mitochondrial ATP synthesis coupled proton transport 1/566 19/18722 0.442086347898754 0.625411001221878 STOML2 1 GO:0043031 negative regulation of macrophage activation 1/566 19/18722 0.442086347898754 0.625411001221878 GRN 1 GO:0044003 modulation by symbiont of host process 1/566 19/18722 0.442086347898754 0.625411001221878 DAG1 1 GO:0044320 cellular response to leptin stimulus 1/566 19/18722 0.442086347898754 0.625411001221878 CCNA2 1 GO:0045618 positive regulation of keratinocyte differentiation 1/566 19/18722 0.442086347898754 0.625411001221878 NME2 1 GO:0045821 positive regulation of glycolytic process 1/566 19/18722 0.442086347898754 0.625411001221878 APP 1 GO:0051957 positive regulation of amino acid transport 1/566 19/18722 0.442086347898754 0.625411001221878 ITGB1 1 GO:0061323 cell proliferation involved in heart morphogenesis 1/566 19/18722 0.442086347898754 0.625411001221878 ISL1 1 GO:0062099 negative regulation of programmed necrotic cell death 1/566 19/18722 0.442086347898754 0.625411001221878 YBX3 1 GO:0070262 peptidyl-serine dephosphorylation 1/566 19/18722 0.442086347898754 0.625411001221878 PPP1CA 1 GO:0071545 inositol phosphate catabolic process 1/566 19/18722 0.442086347898754 0.625411001221878 IMPA2 1 GO:0086014 atrial cardiac muscle cell action potential 1/566 19/18722 0.442086347898754 0.625411001221878 GJA1 1 GO:0086026 atrial cardiac muscle cell to AV node cell signaling 1/566 19/18722 0.442086347898754 0.625411001221878 GJA1 1 GO:0086066 atrial cardiac muscle cell to AV node cell communication 1/566 19/18722 0.442086347898754 0.625411001221878 GJA1 1 GO:0098780 response to mitochondrial depolarisation 1/566 19/18722 0.442086347898754 0.625411001221878 VPS13C 1 GO:1903204 negative regulation of oxidative stress-induced neuron death 1/566 19/18722 0.442086347898754 0.625411001221878 PARK7 1 GO:1903975 regulation of glial cell migration 1/566 19/18722 0.442086347898754 0.625411001221878 LRP1 1 GO:1903978 regulation of microglial cell activation 1/566 19/18722 0.442086347898754 0.625411001221878 GRN 1 GO:2000251 positive regulation of actin cytoskeleton reorganization 1/566 19/18722 0.442086347898754 0.625411001221878 NRP1 1 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation 1/566 19/18722 0.442086347898754 0.625411001221878 HLA-A 1 GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 9/566 273/18722 0.443525318335729 0.627247368878864 CDH1/PTPRF/TENM3/ITGB1/CLSTN1/DSC2/DSC3/PLXNB2/DSG2 9 GO:0001942 hair follicle development 3/566 81/18722 0.445000249286926 0.628335271114937 LAMA5/EGFR/LGR5 3 GO:0030641 regulation of cellular pH 3/566 81/18722 0.445000249286926 0.628335271114937 GRN/ATP6AP1/RAB38 3 GO:0044773 mitotic DNA damage checkpoint signaling 3/566 81/18722 0.445000249286926 0.628335271114937 RPL26/CDK1/TRIAP1 3 GO:0051817 modulation of process of other organism involved in symbiotic interaction 3/566 81/18722 0.445000249286926 0.628335271114937 APOE/CFL1/DAG1 3 GO:1903533 regulation of protein targeting 3/566 81/18722 0.445000249286926 0.628335271114937 UBE2L3/PDCD5/LMAN1 3 GO:0002764 immune response-regulating signaling pathway 15/566 468/18722 0.445689015199494 0.628982458548148 RPS3/HMGB1/HLA-DRB1/TYROBP/FCER1G/HLA-A/HLA-DPB1/CYBA/UBE2N/PHPT1/HSPD1/STOML2/COLEC12/SLC39A10/MNDA 15 GO:0071222 cellular response to lipopolysaccharide 7/566 209/18722 0.445741162785132 0.628982458548148 VIM/HMGB2/HMGB1/GSTP1/CHMP5/ABCA1/SERPINE1 7 GO:0031623 receptor internalization 4/566 113/18722 0.446827557159603 0.630315679491303 FCER1G/LRP1/ITGB1/TFRC 4 GO:0007632 visual behavior 2/566 50/18722 0.448879960102864 0.631609855365977 ITGB1/APP 2 GO:0038202 TORC1 signaling 2/566 50/18722 0.448879960102864 0.631609855365977 PIH1D1/SMG1 2 GO:0043628 ncRNA 3'-end processing 2/566 50/18722 0.448879960102864 0.631609855365977 SSB/EXOSC9 2 GO:0050873 brown fat cell differentiation 2/566 50/18722 0.448879960102864 0.631609855365977 BNIP3/ADRB1 2 GO:0060337 type I interferon signaling pathway 2/566 50/18722 0.448879960102864 0.631609855365977 HSP90AB1/IFITM2 2 GO:0110151 positive regulation of biomineralization 2/566 50/18722 0.448879960102864 0.631609855365977 FBN2/ATP2B1 2 GO:1902930 regulation of alcohol biosynthetic process 2/566 50/18722 0.448879960102864 0.631609855365977 APOE/P2RY6 2 GO:1904738 vascular associated smooth muscle cell migration 2/566 50/18722 0.448879960102864 0.631609855365977 LRP1/IQGAP1 2 GO:0009266 response to temperature stimulus 6/566 178/18722 0.451929353648043 0.635498888958018 HSP90AB1/DNAJA1/HSPD1/CIRBP/ATP2B1/ADRB1 6 GO:0048015 phosphatidylinositol-mediated signaling 6/566 178/18722 0.451929353648043 0.635498888958018 FN1/FLT1/SERPINE2/EGFR/PLXNB1/IGF1R 6 GO:0002312 B cell activation involved in immune response 3/566 82/18722 0.452938847706289 0.63631547806513 LGALS1/HSPD1/TFRC 3 GO:0050000 chromosome localization 3/566 82/18722 0.452938847706289 0.63631547806513 CCNB1/NUDC/CHMP5 3 GO:0060395 SMAD protein signal transduction 3/566 82/18722 0.452938847706289 0.63631547806513 VIM/LRP1/SUB1 3 GO:0007041 lysosomal transport 4/566 114/18722 0.453529620539444 0.636944438688204 LRP1/PSAP/CHMP5/GRN 4 GO:0043543 protein acylation 8/566 243/18722 0.453836305764264 0.637060144038102 MORF4L2/ISL1/PARK7/POLE3/HAT1/NAA20/RUVBL1/PIH1D1 8 GO:0002440 production of molecular mediator of immune response 10/566 308/18722 0.454478125966816 0.637060144038102 CD74/HLA-DRB1/HLA-DPA1/HLA-A/HLA-DRA/HLA-DPB1/B2M/HSPD1/CTNNBL1/TFRC 10 GO:0030100 regulation of endocytosis 7/566 211/18722 0.455561556022261 0.637060144038102 APOC1/APOE/CALM1/LRP1/B2M/ITGAV/SERPINE1 7 GO:0007416 synapse assembly 6/566 179/18722 0.45726046300222 0.637060144038102 CDH1/PLXNB1/CLSTN1/APP/PLXNB2/UBE2V2 6 GO:0002577 regulation of antigen processing and presentation 1/566 20/18722 0.458970223591921 0.637060144038102 CD74 1 GO:0003215 cardiac right ventricle morphogenesis 1/566 20/18722 0.458970223591921 0.637060144038102 ISL1 1 GO:0006525 arginine metabolic process 1/566 20/18722 0.458970223591921 0.637060144038102 ATP2B4 1 GO:0006837 serotonin transport 1/566 20/18722 0.458970223591921 0.637060144038102 SLC6A4 1 GO:0009713 catechol-containing compound biosynthetic process 1/566 20/18722 0.458970223591921 0.637060144038102 PARK7 1 GO:0010042 response to manganese ion 1/566 20/18722 0.458970223591921 0.637060144038102 APP 1 GO:0010801 negative regulation of peptidyl-threonine phosphorylation 1/566 20/18722 0.458970223591921 0.637060144038102 CALM1 1 GO:0010893 positive regulation of steroid biosynthetic process 1/566 20/18722 0.458970223591921 0.637060144038102 CGA 1 GO:0014047 glutamate secretion 1/566 20/18722 0.458970223591921 0.637060144038102 GJA1 1 GO:0031498 chromatin disassembly 1/566 20/18722 0.458970223591921 0.637060144038102 SUPT16H 1 GO:0042423 catecholamine biosynthetic process 1/566 20/18722 0.458970223591921 0.637060144038102 PARK7 1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process 1/566 20/18722 0.458970223591921 0.637060144038102 ITM2B 1 GO:0043011 myeloid dendritic cell differentiation 1/566 20/18722 0.458970223591921 0.637060144038102 ITGB8 1 GO:0043586 tongue development 1/566 20/18722 0.458970223591921 0.637060144038102 EGFR 1 GO:0043651 linoleic acid metabolic process 1/566 20/18722 0.458970223591921 0.637060144038102 GSTP1 1 GO:0043984 histone H4-K16 acetylation 1/566 20/18722 0.458970223591921 0.637060144038102 PIH1D1 1 GO:0045844 positive regulation of striated muscle tissue development 1/566 20/18722 0.458970223591921 0.637060144038102 IGF2 1 GO:0048636 positive regulation of muscle organ development 1/566 20/18722 0.458970223591921 0.637060144038102 IGF2 1 GO:0051004 regulation of lipoprotein lipase activity 1/566 20/18722 0.458970223591921 0.637060144038102 APOC1 1 GO:0060044 negative regulation of cardiac muscle cell proliferation 1/566 20/18722 0.458970223591921 0.637060144038102 GJA1 1 GO:0060252 positive regulation of glial cell proliferation 1/566 20/18722 0.458970223591921 0.637060144038102 EGFR 1 GO:0061318 renal filtration cell differentiation 1/566 20/18722 0.458970223591921 0.637060144038102 IQGAP1 1 GO:0071379 cellular response to prostaglandin stimulus 1/566 20/18722 0.458970223591921 0.637060144038102 P2RY6 1 GO:0072112 glomerular visceral epithelial cell differentiation 1/566 20/18722 0.458970223591921 0.637060144038102 IQGAP1 1 GO:1901386 negative regulation of voltage-gated calcium channel activity 1/566 20/18722 0.458970223591921 0.637060144038102 CALM1 1 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 1/566 20/18722 0.458970223591921 0.637060144038102 PARK7 1 GO:1904263 positive regulation of TORC1 signaling 1/566 20/18722 0.458970223591921 0.637060144038102 PIH1D1 1 GO:1990182 exosomal secretion 1/566 20/18722 0.458970223591921 0.637060144038102 COPS5 1 GO:2000757 negative regulation of peptidyl-lysine acetylation 1/566 20/18722 0.458970223591921 0.637060144038102 PIH1D1 1 GO:0021872 forebrain generation of neurons 2/566 51/18722 0.459049627599783 0.637060144038102 B2M/NRP1 2 GO:0032964 collagen biosynthetic process 2/566 51/18722 0.459049627599783 0.637060144038102 VIM/ENG 2 GO:0045668 negative regulation of osteoblast differentiation 2/566 51/18722 0.459049627599783 0.637060144038102 CRIM1/LRP5 2 GO:0065002 intracellular protein transmembrane transport 2/566 51/18722 0.459049627599783 0.637060144038102 HSPD1/SEC61A1 2 GO:0071622 regulation of granulocyte chemotaxis 2/566 51/18722 0.459049627599783 0.637060144038102 CD74/DPP4 2 GO:1901292 nucleoside phosphate catabolic process 3/566 83/18722 0.460830140341347 0.639331812028568 DUT/DNPH1/NUDT15 3 GO:0051090 regulation of DNA-binding transcription factor activity 14/566 440/18722 0.460978897552593 0.639338956979484 NPM1/RPS3/PPIA/UBE2N/PRDX3/PARK7/ANXA3/TMSB4X/APP/PLPP3/LRP5/SRI/COPS5/TFRC 14 GO:0015698 inorganic anion transport 6/566 180/18722 0.462579138814884 0.641358556837079 VDAC2/VDAC1/SLC26A2/SLC13A4/PCYOX1/P2RY6 6 GO:0006814 sodium ion transport 8/566 245/18722 0.46295447233622 0.64167911296415 ATP2B4/SERPINE2/SLC6A4/SLC38A2/GLRX/SLC38A10/PRSS8/SLC13A4 8 GO:0010212 response to ionizing radiation 5/566 148/18722 0.464735867545073 0.643747380930511 RPL26/ANXA1/CYBA/GPX1/RAD51 5 GO:0035148 tube formation 5/566 148/18722 0.464735867545073 0.643747380930511 PFN1/LRP2/SPINT1/PLXNB2/FOLR1 5 GO:0018107 peptidyl-threonine phosphorylation 4/566 116/18722 0.466852030744364 0.645874841788038 CALM1/CDK1/VRK1/APP 4 GO:0031123 RNA 3'-end processing 4/566 116/18722 0.466852030744364 0.645874841788038 CCNB1/SSB/APP/EXOSC9 4 GO:0035967 cellular response to topologically incorrect protein 4/566 116/18722 0.466852030744364 0.645874841788038 HSPA9/HSPD1/AMFR/COPS5 4 GO:0043200 response to amino acid 4/566 116/18722 0.466852030744364 0.645874841788038 CYBA/GSTP1/COL4A1/HNRNPD 4 GO:0071216 cellular response to biotic stimulus 8/566 246/18722 0.467502374297911 0.645980343084578 VIM/HMGB2/HMGB1/GSTP1/CHMP5/ABCA1/SERPINE1/TXNIP 8 GO:0022404 molting cycle process 3/566 84/18722 0.468672033961931 0.645980343084578 LAMA5/EGFR/LGR5 3 GO:0022405 hair cycle process 3/566 84/18722 0.468672033961931 0.645980343084578 LAMA5/EGFR/LGR5 3 GO:1900542 regulation of purine nucleotide metabolic process 3/566 84/18722 0.468672033961931 0.645980343084578 ENO1/TMSB4X/APP 3 GO:0007129 homologous chromosome pairing at meiosis 2/566 52/18722 0.469109346562562 0.645980343084578 CCNE1/CCNB1IP1 2 GO:0010718 positive regulation of epithelial to mesenchymal transition 2/566 52/18722 0.469109346562562 0.645980343084578 ISL1/ENG 2 GO:0034204 lipid translocation 2/566 52/18722 0.469109346562562 0.645980343084578 ATP10D/ABCA1 2 GO:0035196 production of miRNAs involved in gene silencing by miRNA 2/566 52/18722 0.469109346562562 0.645980343084578 EGFR/HNRNPA2B1 2 GO:0048260 positive regulation of receptor-mediated endocytosis 2/566 52/18722 0.469109346562562 0.645980343084578 B2M/SERPINE1 2 GO:0051496 positive regulation of stress fiber assembly 2/566 52/18722 0.469109346562562 0.645980343084578 S100A10/NRP1 2 GO:0060147 regulation of posttranscriptional gene silencing 2/566 52/18722 0.469109346562562 0.645980343084578 NEAT1/EGFR 2 GO:0071357 cellular response to type I interferon 2/566 52/18722 0.469109346562562 0.645980343084578 HSP90AB1/IFITM2 2 GO:0072132 mesenchyme morphogenesis 2/566 52/18722 0.469109346562562 0.645980343084578 ISL1/ENG 2 GO:0072523 purine-containing compound catabolic process 2/566 52/18722 0.469109346562562 0.645980343084578 DNPH1/NUDT15 2 GO:0048017 inositol lipid-mediated signaling 6/566 182/18722 0.473175898083856 0.645980343084578 FN1/FLT1/SERPINE2/EGFR/PLXNB1/IGF1R 6 GO:0002702 positive regulation of production of molecular mediator of immune response 4/566 117/18722 0.473469491169419 0.645980343084578 CD74/HLA-A/B2M/TFRC 4 GO:0030301 cholesterol transport 4/566 117/18722 0.473469491169419 0.645980343084578 APOC1/APOE/LRP1/ABCA1 4 GO:1903828 negative regulation of cellular protein localization 4/566 117/18722 0.473469491169419 0.645980343084578 DNAJA1/PARK7/TXN/LMAN1 4 GO:0021700 developmental maturation 9/566 280/18722 0.4735025573507 0.645980343084578 PFN1/TYMS/CCNB1/PLXNB1/DAG1/CDC20/CLSTN1/APP/RAB38 9 GO:0031669 cellular response to nutrient levels 7/566 215/18722 0.475090295157229 0.645980343084578 HNRNPA1/AOC1/SLC2A1/SLC38A2/GABARAP/ATP2B1/FOLR1 7 GO:0006244 pyrimidine nucleotide catabolic process 1/566 21/18722 0.475344026043368 0.645980343084578 DUT 1 GO:0007289 spermatid nucleus differentiation 1/566 21/18722 0.475344026043368 0.645980343084578 HMGB2 1 GO:0010766 negative regulation of sodium ion transport 1/566 21/18722 0.475344026043368 0.645980343084578 SERPINE2 1 GO:0010878 cholesterol storage 1/566 21/18722 0.475344026043368 0.645980343084578 ABCA1 1 GO:0016075 rRNA catabolic process 1/566 21/18722 0.475344026043368 0.645980343084578 EXOSC9 1 GO:0030449 regulation of complement activation 1/566 21/18722 0.475344026043368 0.645980343084578 CD46 1 GO:0030502 negative regulation of bone mineralization 1/566 21/18722 0.475344026043368 0.645980343084578 SRGN 1 GO:0032288 myelin assembly 1/566 21/18722 0.475344026043368 0.645980343084578 ITGB4 1 GO:0033762 response to glucagon 1/566 21/18722 0.475344026043368 0.645980343084578 CCNA2 1 GO:0034035 purine ribonucleoside bisphosphate metabolic process 1/566 21/18722 0.475344026043368 0.645980343084578 SLC26A2 1 GO:0034312 diol biosynthetic process 1/566 21/18722 0.475344026043368 0.645980343084578 ASAH1 1 GO:0034471 ncRNA 5'-end processing 1/566 21/18722 0.475344026043368 0.645980343084578 SSB 1 GO:0035020 regulation of Rac protein signal transduction 1/566 21/18722 0.475344026043368 0.645980343084578 GABARAP 1 GO:0035455 response to interferon-alpha 1/566 21/18722 0.475344026043368 0.645980343084578 IFITM2 1 GO:0044342 type B pancreatic cell proliferation 1/566 21/18722 0.475344026043368 0.645980343084578 SERPINB1 1 GO:0045717 negative regulation of fatty acid biosynthetic process 1/566 21/18722 0.475344026043368 0.645980343084578 APOC1 1 GO:0046597 negative regulation of viral entry into host cell 1/566 21/18722 0.475344026043368 0.645980343084578 IFITM2 1 GO:0046599 regulation of centriole replication 1/566 21/18722 0.475344026043368 0.645980343084578 NPM1 1 GO:0046641 positive regulation of alpha-beta T cell proliferation 1/566 21/18722 0.475344026043368 0.645980343084578 HLA-A 1 GO:0048199 vesicle targeting, to, from or within Golgi 1/566 21/18722 0.475344026043368 0.645980343084578 TFG 1 GO:0048714 positive regulation of oligodendrocyte differentiation 1/566 21/18722 0.475344026043368 0.645980343084578 DAG1 1 GO:0048745 smooth muscle tissue development 1/566 21/18722 0.475344026043368 0.645980343084578 ENG 1 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process 1/566 21/18722 0.475344026043368 0.645980343084578 SLC26A2 1 GO:0050802 circadian sleep/wake cycle, sleep 1/566 21/18722 0.475344026043368 0.645980343084578 ADRB1 1 GO:0050849 negative regulation of calcium-mediated signaling 1/566 21/18722 0.475344026043368 0.645980343084578 ATP2B4 1 GO:0051152 positive regulation of smooth muscle cell differentiation 1/566 21/18722 0.475344026043368 0.645980343084578 ENG 1 GO:0051767 nitric-oxide synthase biosynthetic process 1/566 21/18722 0.475344026043368 0.645980343084578 GSTP1 1 GO:0051769 regulation of nitric-oxide synthase biosynthetic process 1/566 21/18722 0.475344026043368 0.645980343084578 GSTP1 1 GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response 1/566 21/18722 0.475344026043368 0.645980343084578 CD74 1 GO:0072311 glomerular epithelial cell differentiation 1/566 21/18722 0.475344026043368 0.645980343084578 IQGAP1 1 GO:0090141 positive regulation of mitochondrial fission 1/566 21/18722 0.475344026043368 0.645980343084578 BNIP3 1 GO:0097734 extracellular exosome biogenesis 1/566 21/18722 0.475344026043368 0.645980343084578 COPS5 1 GO:0150105 protein localization to cell-cell junction 1/566 21/18722 0.475344026043368 0.645980343084578 ACTG1 1 GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 1/566 21/18722 0.475344026043368 0.645980343084578 SLC25A5 1 GO:1901863 positive regulation of muscle tissue development 1/566 21/18722 0.475344026043368 0.645980343084578 IGF2 1 GO:1902307 positive regulation of sodium ion transmembrane transport 1/566 21/18722 0.475344026043368 0.645980343084578 GLRX 1 GO:1902473 regulation of protein localization to synapse 1/566 21/18722 0.475344026043368 0.645980343084578 DAG1 1 GO:2000291 regulation of myoblast proliferation 1/566 21/18722 0.475344026043368 0.645980343084578 MALAT1 1 GO:0010507 negative regulation of autophagy 3/566 85/18722 0.476462534803466 0.646119770010671 QSOX1/MET/SMG1 3 GO:0044774 mitotic DNA integrity checkpoint signaling 3/566 85/18722 0.476462534803466 0.646119770010671 RPL26/CDK1/TRIAP1 3 GO:0055013 cardiac muscle cell development 3/566 85/18722 0.476462534803466 0.646119770010671 CCNB1/ISL1/CDK1 3 GO:0071277 cellular response to calcium ion 3/566 85/18722 0.476462534803466 0.646119770010671 CACYBP/LGMN/IQGAP1 3 GO:0097006 regulation of plasma lipoprotein particle levels 3/566 85/18722 0.476462534803466 0.646119770010671 APOC1/APOE/ABCA1 3 GO:0098773 skin epidermis development 3/566 85/18722 0.476462534803466 0.646119770010671 LAMA5/EGFR/LGR5 3 GO:2000779 regulation of double-strand break repair 3/566 85/18722 0.476462534803466 0.646119770010671 DEK/RAD51/PPP4C 3 GO:0016925 protein sumoylation 2/566 53/18722 0.479056463275002 0.648452226968777 SUMO2/PARK7 2 GO:0034381 plasma lipoprotein particle clearance 2/566 53/18722 0.479056463275002 0.648452226968777 APOC1/APOE 2 GO:0045806 negative regulation of endocytosis 2/566 53/18722 0.479056463275002 0.648452226968777 APOC1/ITGAV 2 GO:0060966 regulation of gene silencing by RNA 2/566 53/18722 0.479056463275002 0.648452226968777 NEAT1/EGFR 2 GO:0071320 cellular response to cAMP 2/566 53/18722 0.479056463275002 0.648452226968777 AKAP9/APP 2 GO:1990090 cellular response to nerve growth factor stimulus 2/566 53/18722 0.479056463275002 0.648452226968777 EIF4A3/APP 2 GO:0007613 memory 4/566 118/18722 0.480055941755032 0.649410225674081 APOE/LGMN/SLC6A4/SERPINF1 4 GO:0045446 endothelial cell differentiation 4/566 118/18722 0.480055941755032 0.649410225674081 FSTL1/GPX1/MET/NRP1 4 GO:0043087 regulation of GTPase activity 11/566 348/18722 0.483376998436657 0.65370425183475 STMN1/ZC3H15/ITGA6/PLXNA1/S100A10/PLXNB1/MET/ITGB1/IQGAP1/PLXNB2/ADRB1 11 GO:0006140 regulation of nucleotide metabolic process 3/566 86/18722 0.484199746592842 0.654618060076323 ENO1/TMSB4X/APP 3 GO:0030282 bone mineralization 4/566 119/18722 0.486610055172877 0.655553181179092 FBN2/SRGN/GPNMB/ATP2B1 4 GO:0021915 neural tube development 5/566 152/18722 0.488024543784953 0.655553181179092 PFN1/LRP2/SPINT1/PLXNB2/FOLR1 5 GO:0031050 dsRNA processing 2/566 54/18722 0.488888584240828 0.655553181179092 EGFR/HNRNPA2B1 2 GO:0043647 inositol phosphate metabolic process 2/566 54/18722 0.488888584240828 0.655553181179092 IMPA2/P2RY6 2 GO:0070228 regulation of lymphocyte apoptotic process 2/566 54/18722 0.488888584240828 0.655553181179092 CD74/SLC39A10 2 GO:0070918 production of small RNA involved in gene silencing by RNA 2/566 54/18722 0.488888584240828 0.655553181179092 EGFR/HNRNPA2B1 2 GO:2000179 positive regulation of neural precursor cell proliferation 2/566 54/18722 0.488888584240828 0.655553181179092 LRP2/ADGRG1 2 GO:0042742 defense response to bacterium 11/566 350/18722 0.491016695525001 0.655553181179092 LYZ/HMGB2/FCER1G/HLA-A/PRG2/CYBA/RPS19/ANXA3/GRN/COLEC12/SERPINE1 11 GO:0002053 positive regulation of mesenchymal cell proliferation 1/566 22/18722 0.491223138457649 0.655553181179092 LRP5 1 GO:0002220 innate immune response activating cell surface receptor signaling pathway 1/566 22/18722 0.491223138457649 0.655553181179092 TYROBP 1 GO:0006662 glycerol ether metabolic process 1/566 22/18722 0.491223138457649 0.655553181179092 TXN 1 GO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization 1/566 22/18722 0.491223138457649 0.655553181179092 FOLR1 1 GO:0007413 axonal fasciculation 1/566 22/18722 0.491223138457649 0.655553181179092 NRP1 1 GO:0019400 alditol metabolic process 1/566 22/18722 0.491223138457649 0.655553181179092 TPI1 1 GO:0021854 hypothalamus development 1/566 22/18722 0.491223138457649 0.655553181179092 NRP1 1 GO:0031061 negative regulation of histone methylation 1/566 22/18722 0.491223138457649 0.655553181179092 PIH1D1 1 GO:0032693 negative regulation of interleukin-10 production 1/566 22/18722 0.491223138457649 0.655553181179092 TYROBP 1 GO:0032816 positive regulation of natural killer cell activation 1/566 22/18722 0.491223138457649 0.655553181179092 TYROBP 1 GO:0032891 negative regulation of organic acid transport 1/566 22/18722 0.491223138457649 0.655553181179092 SLC43A2 1 GO:0034629 cellular protein-containing complex localization 1/566 22/18722 0.491223138457649 0.655553181179092 AKAP9 1 GO:0034755 iron ion transmembrane transport 1/566 22/18722 0.491223138457649 0.655553181179092 SLC40A1 1 GO:0035561 regulation of chromatin binding 1/566 22/18722 0.491223138457649 0.655553181179092 GMNN 1 GO:0036120 cellular response to platelet-derived growth factor stimulus 1/566 22/18722 0.491223138457649 0.655553181179092 CCNA2 1 GO:0042749 regulation of circadian sleep/wake cycle 1/566 22/18722 0.491223138457649 0.655553181179092 ADRB1 1 GO:0043486 histone exchange 1/566 22/18722 0.491223138457649 0.655553181179092 ITGB3BP 1 GO:0045048 protein insertion into ER membrane 1/566 22/18722 0.491223138457649 0.655553181179092 EMC1 1 GO:0045061 thymic T cell selection 1/566 22/18722 0.491223138457649 0.655553181179092 CD74 1 GO:0045540 regulation of cholesterol biosynthetic process 1/566 22/18722 0.491223138457649 0.655553181179092 APOE 1 GO:0045624 positive regulation of T-helper cell differentiation 1/566 22/18722 0.491223138457649 0.655553181179092 ANXA1 1 GO:0046628 positive regulation of insulin receptor signaling pathway 1/566 22/18722 0.491223138457649 0.655553181179092 IGF2 1 GO:0048169 regulation of long-term neuronal synaptic plasticity 1/566 22/18722 0.491223138457649 0.655553181179092 APP 1 GO:0050860 negative regulation of T cell receptor signaling pathway 1/566 22/18722 0.491223138457649 0.655553181179092 PHPT1 1 GO:0055093 response to hyperoxia 1/566 22/18722 0.491223138457649 0.655553181179092 BNIP3 1 GO:0060343 trabecula formation 1/566 22/18722 0.491223138457649 0.655553181179092 FBN2 1 GO:0060444 branching involved in mammary gland duct morphogenesis 1/566 22/18722 0.491223138457649 0.655553181179092 LRP5 1 GO:0060563 neuroepithelial cell differentiation 1/566 22/18722 0.491223138457649 0.655553181179092 SERPINE1 1 GO:0060713 labyrinthine layer morphogenesis 1/566 22/18722 0.491223138457649 0.655553181179092 SPINT1 1 GO:0060965 negative regulation of gene silencing by miRNA 1/566 22/18722 0.491223138457649 0.655553181179092 NEAT1 1 GO:0061042 vascular wound healing 1/566 22/18722 0.491223138457649 0.655553181179092 SERPINE1 1 GO:0099563 modification of synaptic structure 1/566 22/18722 0.491223138457649 0.655553181179092 PFN1 1 GO:0106030 neuron projection fasciculation 1/566 22/18722 0.491223138457649 0.655553181179092 NRP1 1 GO:0106118 regulation of sterol biosynthetic process 1/566 22/18722 0.491223138457649 0.655553181179092 APOE 1 GO:2000773 negative regulation of cellular senescence 1/566 22/18722 0.491223138457649 0.655553181179092 YBX1 1 GO:0007029 endoplasmic reticulum organization 3/566 87/18722 0.491881868539079 0.656038969064104 LMAN1/EMC1/SEC61A1 3 GO:0016101 diterpenoid metabolic process 3/566 87/18722 0.491881868539079 0.656038969064104 LRP2/LRP1/EGFR 3 GO:0048593 camera-type eye morphogenesis 4/566 120/18722 0.493130549855969 0.657507399807959 HMGN1/TENM3/LRP5/NAGLU 4 GO:0022412 cellular process involved in reproduction in multicellular organism 12/566 384/18722 0.494853214027238 0.659606739176426 RPS6/DYNLL1/HMGB2/CCNB1/LGR5/ITGB1/EIF2S2/CCNB2/CCNB1IP1/HEXB/PAQR7/FOLR1 12 GO:0006360 transcription by RNA polymerase I 2/566 55/18722 0.498603562925094 0.664207977900215 NCL/PIH1D1 2 GO:0043331 response to dsRNA 2/566 55/18722 0.498603562925094 0.664207977900215 NPM1/COLEC12 2 GO:0007204 positive regulation of cytosolic calcium ion concentration 10/566 319/18722 0.49877466614454 0.664237156349234 HMGB1/CALM1/ATP2B4/LRP1/CYBA/ITGAV/GSTO1/SRI/GJA1/P2RY6 10 GO:0034612 response to tumor necrosis factor 8/566 253/18722 0.499079667461868 0.664444581202224 RPS3/YBX3/CYBA/GSTP1/KRT8/TMSB4X/KRT18/ASAH1 8 GO:0002224 toll-like receptor signaling pathway 4/566 121/18722 0.499616189618056 0.664562675882756 HMGB1/CYBA/HSPD1/COLEC12 4 GO:0003206 cardiac chamber morphogenesis 4/566 121/18722 0.499616189618056 0.664562675882756 LRP2/ISL1/NRP1/ENG 4 GO:0038127 ERBB signaling pathway 4/566 121/18722 0.499616189618056 0.664562675882756 EGFR/LGMN/EFEMP1/IQGAP1 4 GO:0051480 regulation of cytosolic calcium ion concentration 11/566 353/18722 0.50242720798996 0.665923615281227 HMGB1/CALM1/ATP2B4/LRP1/CYBA/ITGAV/GSTO1/SRI/GJA1/ATP2B1/P2RY6 11 GO:0008406 gonad development 7/566 221/18722 0.504026430510308 0.665923615281227 LRP2/HMGB2/YBX3/ADGRG1/CGA/EIF2S2/MEA1 7 GO:0071219 cellular response to molecule of bacterial origin 7/566 221/18722 0.504026430510308 0.665923615281227 VIM/HMGB2/HMGB1/GSTP1/CHMP5/ABCA1/SERPINE1 7 GO:0046434 organophosphate catabolic process 5/566 155/18722 0.505251484780632 0.665923615281227 APOC1/DUT/IMPA2/DNPH1/NUDT15 5 GO:0000966 RNA 5'-end processing 1/566 23/18722 0.506622480897915 0.665923615281227 SSB 1 GO:0001919 regulation of receptor recycling 1/566 23/18722 0.506622480897915 0.665923615281227 CHMP5 1 GO:0002082 regulation of oxidative phosphorylation 1/566 23/18722 0.506622480897915 0.665923615281227 COX7A2L 1 GO:0002758 innate immune response-activating signal transduction 1/566 23/18722 0.506622480897915 0.665923615281227 TYROBP 1 GO:0003283 atrial septum development 1/566 23/18722 0.506622480897915 0.665923615281227 ISL1 1 GO:0006541 glutamine metabolic process 1/566 23/18722 0.506622480897915 0.665923615281227 GMPS 1 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway 1/566 23/18722 0.506622480897915 0.665923615281227 LRP1 1 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway 1/566 23/18722 0.506622480897915 0.665923615281227 GSTP1 1 GO:0019430 removal of superoxide radicals 1/566 23/18722 0.506622480897915 0.665923615281227 PRDX1 1 GO:0021871 forebrain regionalization 1/566 23/18722 0.506622480897915 0.665923615281227 ADGRG1 1 GO:0021884 forebrain neuron development 1/566 23/18722 0.506622480897915 0.665923615281227 NRP1 1 GO:0030194 positive regulation of blood coagulation 1/566 23/18722 0.506622480897915 0.665923615281227 SERPINE1 1 GO:0031338 regulation of vesicle fusion 1/566 23/18722 0.506622480897915 0.665923615281227 ANXA1 1 GO:0033081 regulation of T cell differentiation in thymus 1/566 23/18722 0.506622480897915 0.665923615281227 CLPTM1 1 GO:0034695 response to prostaglandin E 1/566 23/18722 0.506622480897915 0.665923615281227 P2RY6 1 GO:0036119 response to platelet-derived growth factor 1/566 23/18722 0.506622480897915 0.665923615281227 CCNA2 1 GO:0036303 lymph vessel morphogenesis 1/566 23/18722 0.506622480897915 0.665923615281227 SVEP1 1 GO:0040019 positive regulation of embryonic development 1/566 23/18722 0.506622480897915 0.665923615281227 CFL1 1 GO:0043931 ossification involved in bone maturation 1/566 23/18722 0.506622480897915 0.665923615281227 PLXNB1 1 GO:0045932 negative regulation of muscle contraction 1/566 23/18722 0.506622480897915 0.665923615281227 SRI 1 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process 1/566 23/18722 0.506622480897915 0.665923615281227 CHPF 1 GO:0050765 negative regulation of phagocytosis 1/566 23/18722 0.506622480897915 0.665923615281227 HMGB1 1 GO:0051349 positive regulation of lyase activity 1/566 23/18722 0.506622480897915 0.665923615281227 PARK7 1 GO:0051590 positive regulation of neurotransmitter transport 1/566 23/18722 0.506622480897915 0.665923615281227 ITGB1 1 GO:0060143 positive regulation of syncytium formation by plasma membrane fusion 1/566 23/18722 0.506622480897915 0.665923615281227 TYROBP 1 GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization 1/566 23/18722 0.506622480897915 0.665923615281227 AKAP9 1 GO:0060353 regulation of cell adhesion molecule production 1/566 23/18722 0.506622480897915 0.665923615281227 COLEC12 1 GO:0060547 negative regulation of necrotic cell death 1/566 23/18722 0.506622480897915 0.665923615281227 YBX3 1 GO:0071305 cellular response to vitamin D 1/566 23/18722 0.506622480897915 0.665923615281227 ATP2B1 1 GO:0071514 genetic imprinting 1/566 23/18722 0.506622480897915 0.665923615281227 IGF2 1 GO:0071636 positive regulation of transforming growth factor beta production 1/566 23/18722 0.506622480897915 0.665923615281227 CD46 1 GO:0140112 extracellular vesicle biogenesis 1/566 23/18722 0.506622480897915 0.665923615281227 COPS5 1 GO:1900048 positive regulation of hemostasis 1/566 23/18722 0.506622480897915 0.665923615281227 SERPINE1 1 GO:1902410 mitotic cytokinetic process 1/566 23/18722 0.506622480897915 0.665923615281227 CHMP5 1 GO:2000737 negative regulation of stem cell differentiation 1/566 23/18722 0.506622480897915 0.665923615281227 HSPA9 1 GO:2000810 regulation of bicellular tight junction assembly 1/566 23/18722 0.506622480897915 0.665923615281227 GJA1 1 GO:0015800 acidic amino acid transport 2/566 56/18722 0.508199487057073 0.666226182679061 ITGB1/GJA1 2 GO:0022029 telencephalon cell migration 2/566 56/18722 0.508199487057073 0.666226182679061 ADGRG1/LAMB1 2 GO:0030166 proteoglycan biosynthetic process 2/566 56/18722 0.508199487057073 0.666226182679061 CHPF/HS6ST2 2 GO:0031122 cytoplasmic microtubule organization 2/566 56/18722 0.508199487057073 0.666226182679061 TUBGCP2/CLIP1 2 GO:0031529 ruffle organization 2/566 56/18722 0.508199487057073 0.666226182679061 PFN1/AIF1 2 GO:0032608 interferon-beta production 2/566 56/18722 0.508199487057073 0.666226182679061 HMGB2/HMGB1 2 GO:0032648 regulation of interferon-beta production 2/566 56/18722 0.508199487057073 0.666226182679061 HMGB2/HMGB1 2 GO:0045071 negative regulation of viral genome replication 2/566 56/18722 0.508199487057073 0.666226182679061 BANF1/IFITM2 2 GO:1990089 response to nerve growth factor 2/566 56/18722 0.508199487057073 0.666226182679061 EIF4A3/APP 2 GO:0001764 neuron migration 5/566 156/18722 0.510943233278722 0.669428862435806 ADGRG1/NRP1/PLXNB2/TUBGCP2/SEMA6A 5 GO:0009267 cellular response to starvation 5/566 156/18722 0.510943233278722 0.669428862435806 HNRNPA1/AOC1/SLC2A1/SLC38A2/GABARAP 5 GO:0006400 tRNA modification 3/566 90/18722 0.514581076666016 0.673996750019742 SSB/TRMT112/TPRKB 3 GO:0051656 establishment of organelle localization 12/566 390/18722 0.516591203072038 0.675796083471644 NPM1/RAN/MAD2L1/CCNB1/NUDC/CHMP5/CFL1/ITGB1/PDCD10/TFG/GJA1/ATP6AP1 12 GO:0007030 Golgi organization 5/566 157/18722 0.51660825385484 0.675796083471644 CDK1/PDCD10/AKAP9/VRK1/LMAN1 5 GO:0007034 vacuolar transport 5/566 157/18722 0.51660825385484 0.675796083471644 LRP1/PSAP/CHMP5/GRN/VPS13C 5 GO:0002011 morphogenesis of an epithelial sheet 2/566 57/18722 0.517674666472906 0.675796083471644 DAG1/PDCD10 2 GO:0016447 somatic recombination of immunoglobulin gene segments 2/566 57/18722 0.517674666472906 0.675796083471644 HSPD1/TFRC 2 GO:0030219 megakaryocyte differentiation 2/566 57/18722 0.517674666472906 0.675796083471644 HMGB2/SCIN 2 GO:0050879 multicellular organismal movement 2/566 57/18722 0.517674666472906 0.675796083471644 GSTO1/GAA 2 GO:0050881 musculoskeletal movement 2/566 57/18722 0.517674666472906 0.675796083471644 GSTO1/GAA 2 GO:0050891 multicellular organismal water homeostasis 2/566 57/18722 0.517674666472906 0.675796083471644 STMN1/MET 2 GO:0060042 retina morphogenesis in camera-type eye 2/566 57/18722 0.517674666472906 0.675796083471644 LRP5/NAGLU 2 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1/566 24/18722 0.521556524205673 0.675796083471644 EXOSC9 1 GO:0001702 gastrulation with mouth forming second 1/566 24/18722 0.521556524205673 0.675796083471644 LRP5 1 GO:0002438 acute inflammatory response to antigenic stimulus 1/566 24/18722 0.521556524205673 0.675796083471644 PARK7 1 GO:0002755 MyD88-dependent toll-like receptor signaling pathway 1/566 24/18722 0.521556524205673 0.675796083471644 HSPD1 1 GO:0007035 vacuolar acidification 1/566 24/18722 0.521556524205673 0.675796083471644 GRN 1 GO:0016486 peptide hormone processing 1/566 24/18722 0.521556524205673 0.675796083471644 MME 1 GO:0022410 circadian sleep/wake cycle process 1/566 24/18722 0.521556524205673 0.675796083471644 ADRB1 1 GO:0030878 thyroid gland development 1/566 24/18722 0.521556524205673 0.675796083471644 CGA 1 GO:0036010 protein localization to endosome 1/566 24/18722 0.521556524205673 0.675796083471644 NRP1 1 GO:0038095 Fc-epsilon receptor signaling pathway 1/566 24/18722 0.521556524205673 0.675796083471644 FCER1G 1 GO:0050687 negative regulation of defense response to virus 1/566 24/18722 0.521556524205673 0.675796083471644 HTRA1 1 GO:0050820 positive regulation of coagulation 1/566 24/18722 0.521556524205673 0.675796083471644 SERPINE1 1 GO:0050855 regulation of B cell receptor signaling pathway 1/566 24/18722 0.521556524205673 0.675796083471644 SLC39A10 1 GO:0051123 RNA polymerase II preinitiation complex assembly 1/566 24/18722 0.521556524205673 0.675796083471644 HMGB1 1 GO:0051570 regulation of histone H3-K9 methylation 1/566 24/18722 0.521556524205673 0.675796083471644 PIH1D1 1 GO:0060149 negative regulation of posttranscriptional gene silencing 1/566 24/18722 0.521556524205673 0.675796083471644 NEAT1 1 GO:0060561 apoptotic process involved in morphogenesis 1/566 24/18722 0.521556524205673 0.675796083471644 LRP5 1 GO:0060967 negative regulation of gene silencing by RNA 1/566 24/18722 0.521556524205673 0.675796083471644 NEAT1 1 GO:0070129 regulation of mitochondrial translation 1/566 24/18722 0.521556524205673 0.675796083471644 MALSU1 1 GO:0071294 cellular response to zinc ion 1/566 24/18722 0.521556524205673 0.675796083471644 MT2A 1 GO:0071577 zinc ion transmembrane transport 1/566 24/18722 0.521556524205673 0.675796083471644 SLC39A10 1 GO:0072010 glomerular epithelium development 1/566 24/18722 0.521556524205673 0.675796083471644 IQGAP1 1 GO:0090023 positive regulation of neutrophil chemotaxis 1/566 24/18722 0.521556524205673 0.675796083471644 CD74 1 GO:2000209 regulation of anoikis 1/566 24/18722 0.521556524205673 0.675796083471644 ITGB1 1 GO:2000310 regulation of NMDA receptor activity 1/566 24/18722 0.521556524205673 0.675796083471644 APP 1 GO:2000679 positive regulation of transcription regulatory region DNA binding 1/566 24/18722 0.521556524205673 0.675796083471644 PARK7 1 GO:0002065 columnar/cuboidal epithelial cell differentiation 3/566 91/18722 0.522026669150715 0.675796083471644 IL6ST/TYMS/SERPINE1 3 GO:0006885 regulation of pH 3/566 91/18722 0.522026669150715 0.675796083471644 GRN/ATP6AP1/RAB38 3 GO:0055006 cardiac cell development 3/566 91/18722 0.522026669150715 0.675796083471644 CCNB1/ISL1/CDK1 3 GO:0098661 inorganic anion transmembrane transport 3/566 91/18722 0.522026669150715 0.675796083471644 SLC26A2/SLC13A4/PCYOX1 3 GO:0002931 response to ischemia 2/566 58/18722 0.52702762147706 0.681675470893629 HSPD1/GJA1 2 GO:0034340 response to type I interferon 2/566 58/18722 0.52702762147706 0.681675470893629 HSP90AB1/IFITM2 2 GO:0043525 positive regulation of neuron apoptotic process 2/566 58/18722 0.52702762147706 0.681675470893629 TYROBP/GRN 2 GO:0001708 cell fate specification 3/566 92/18722 0.529409527981643 0.684332429355165 ISL1/NRP1/ITGB1 3 GO:0048525 negative regulation of viral process 3/566 92/18722 0.529409527981643 0.684332429355165 PPIA/BANF1/IFITM2 3 GO:0048568 embryonic organ development 13/566 427/18722 0.529542951286735 0.684332429355165 KRT19/FBN2/FBN1/EIF4A3/RPL10/KRT8/RPL38/SPINT1/ENG/EFEMP1/IGF2/NAGLU/FOLR1 13 GO:0045137 development of primary sexual characteristics 7/566 227/18722 0.532420600336334 0.685842138241662 LRP2/HMGB2/YBX3/ADGRG1/CGA/EIF2S2/MEA1 7 GO:0015012 heparan sulfate proteoglycan biosynthetic process 1/566 25/18722 0.536039303502902 0.685842138241662 HS6ST2 1 GO:0031579 membrane raft organization 1/566 25/18722 0.536039303502902 0.685842138241662 S100A10 1 GO:0032331 negative regulation of chondrocyte differentiation 1/566 25/18722 0.536039303502902 0.685842138241662 EFEMP1 1 GO:0032469 endoplasmic reticulum calcium ion homeostasis 1/566 25/18722 0.536039303502902 0.685842138241662 APP 1 GO:0032753 positive regulation of interleukin-4 production 1/566 25/18722 0.536039303502902 0.685842138241662 FCER1G 1 GO:0033233 regulation of protein sumoylation 1/566 25/18722 0.536039303502902 0.685842138241662 PARK7 1 GO:0033622 integrin activation 1/566 25/18722 0.536039303502902 0.685842138241662 FN1 1 GO:0034389 lipid droplet organization 1/566 25/18722 0.536039303502902 0.685842138241662 PPIA 1 GO:0042730 fibrinolysis 1/566 25/18722 0.536039303502902 0.685842138241662 SERPINE1 1 GO:0045109 intermediate filament organization 1/566 25/18722 0.536039303502902 0.685842138241662 VIM 1 GO:0045324 late endosome to vacuole transport 1/566 25/18722 0.536039303502902 0.685842138241662 CHMP5 1 GO:0045822 negative regulation of heart contraction 1/566 25/18722 0.536039303502902 0.685842138241662 SRI 1 GO:0050995 negative regulation of lipid catabolic process 1/566 25/18722 0.536039303502902 0.685842138241662 APOC1 1 GO:0062009 secondary palate development 1/566 25/18722 0.536039303502902 0.685842138241662 ITGB8 1 GO:0071450 cellular response to oxygen radical 1/566 25/18722 0.536039303502902 0.685842138241662 PRDX1 1 GO:0071451 cellular response to superoxide 1/566 25/18722 0.536039303502902 0.685842138241662 PRDX1 1 GO:0090169 regulation of spindle assembly 1/566 25/18722 0.536039303502902 0.685842138241662 CHMP5 1 GO:0090382 phagosome maturation 1/566 25/18722 0.536039303502902 0.685842138241662 RAB38 1 GO:0098703 calcium ion import across plasma membrane 1/566 25/18722 0.536039303502902 0.685842138241662 ATP2B4 1 GO:0099560 synaptic membrane adhesion 1/566 25/18722 0.536039303502902 0.685842138241662 PTPRF 1 GO:0140448 signaling receptor ligand precursor processing 1/566 25/18722 0.536039303502902 0.685842138241662 MME 1 GO:1900078 positive regulation of cellular response to insulin stimulus 1/566 25/18722 0.536039303502902 0.685842138241662 IGF2 1 GO:1902932 positive regulation of alcohol biosynthetic process 1/566 25/18722 0.536039303502902 0.685842138241662 P2RY6 1 GO:1903055 positive regulation of extracellular matrix organization 1/566 25/18722 0.536039303502902 0.685842138241662 DAG1 1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis 1/566 25/18722 0.536039303502902 0.685842138241662 PDCD10 1 GO:1903792 negative regulation of anion transport 1/566 25/18722 0.536039303502902 0.685842138241662 SLC43A2 1 GO:1903798 regulation of production of miRNAs involved in gene silencing by miRNA 1/566 25/18722 0.536039303502902 0.685842138241662 EGFR 1 GO:1904385 cellular response to angiotensin 1/566 25/18722 0.536039303502902 0.685842138241662 CYBA 1 GO:1905563 negative regulation of vascular endothelial cell proliferation 1/566 25/18722 0.536039303502902 0.685842138241662 FLT1 1 GO:0019369 arachidonic acid metabolic process 2/566 59/18722 0.536257071702432 0.685842138241662 PTGES3/GPX1 2 GO:0021885 forebrain cell migration 2/566 59/18722 0.536257071702432 0.685842138241662 ADGRG1/LAMB1 2 GO:0030042 actin filament depolymerization 2/566 59/18722 0.536257071702432 0.685842138241662 CFL1/SCIN 2 GO:0048010 vascular endothelial growth factor receptor signaling pathway 2/566 59/18722 0.536257071702432 0.685842138241662 FLT1/NRP1 2 GO:0051055 negative regulation of lipid biosynthetic process 2/566 59/18722 0.536257071702432 0.685842138241662 APOC1/APOE 2 GO:0051568 histone H3-K4 methylation 2/566 59/18722 0.536257071702432 0.685842138241662 DPY30/PIH1D1 2 GO:0019217 regulation of fatty acid metabolic process 3/566 93/18722 0.536728381781279 0.685853833435779 CD74/APOC1/ANXA1 3 GO:0033108 mitochondrial respiratory chain complex assembly 3/566 93/18722 0.536728381781279 0.685853833435779 NDUFB3/NDUFA10/NDUFS3 3 GO:0045132 meiotic chromosome segregation 3/566 93/18722 0.536728381781279 0.685853833435779 CCNE1/PTTG1/CCNB1IP1 3 GO:0008033 tRNA processing 4/566 127/18722 0.537734456376074 0.686548264922936 LSM6/SSB/TRMT112/TPRKB 4 GO:0035270 endocrine system development 4/566 127/18722 0.537734456376074 0.686548264922936 ANXA1/CDH1/ISL1/CGA 4 GO:0048565 digestive tract development 4/566 127/18722 0.537734456376074 0.686548264922936 IL6ST/TYMS/CCNB1/EGFR 4 GO:0003205 cardiac chamber development 5/566 161/18722 0.538984859340424 0.687947417942536 LRP2/ADAMTS6/ISL1/NRP1/ENG 5 GO:1901605 alpha-amino acid metabolic process 6/566 195/18722 0.540343126403018 0.689483404627755 ATP2B4/SMS/PARK7/GCSH/MTHFS/GMPS 6 GO:0001738 morphogenesis of a polarized epithelium 3/566 94/18722 0.543982040047289 0.693133383597748 LAMA5/ACTG1/ZNRF3 3 GO:0010389 regulation of G2/M transition of mitotic cell cycle 3/566 94/18722 0.543982040047289 0.693133383597748 CCNB1/CDK1/APP 3 GO:0019080 viral gene expression 3/566 94/18722 0.543982040047289 0.693133383597748 SSB/CANX/MOGS 3 GO:0061326 renal tubule development 3/566 94/18722 0.543982040047289 0.693133383597748 LAMA5/COL4A1/LGR5 3 GO:1902414 protein localization to cell junction 3/566 94/18722 0.543982040047289 0.693133383597748 ACTG1/DAG1/CLSTN1 3 GO:0002712 regulation of B cell mediated immunity 2/566 60/18722 0.545361925449668 0.693600179671634 CD46/TFRC 2 GO:0002889 regulation of immunoglobulin mediated immune response 2/566 60/18722 0.545361925449668 0.693600179671634 CD46/TFRC 2 GO:0006893 Golgi to plasma membrane transport 2/566 60/18722 0.545361925449668 0.693600179671634 KRT18/MACF1 2 GO:0051851 modulation by host of symbiont process 2/566 60/18722 0.545361925449668 0.693600179671634 APOE/CFL1 2 GO:0051965 positive regulation of synapse assembly 2/566 60/18722 0.545361925449668 0.693600179671634 CLSTN1/UBE2V2 2 GO:0061951 establishment of protein localization to plasma membrane 2/566 60/18722 0.545361925449668 0.693600179671634 KRT18/MACF1 2 GO:0019216 regulation of lipid metabolic process 10/566 331/18722 0.545955148126027 0.693600179671634 CD74/APOC1/APOE/FLT1/ANXA1/PSAP/CGA/STOML2/ASAH1/RAB38 10 GO:0001556 oocyte maturation 1/566 26/18722 0.550084431289037 0.693600179671634 CCNB1 1 GO:0014829 vascular associated smooth muscle contraction 1/566 26/18722 0.550084431289037 0.693600179671634 ATP2B1 1 GO:0015985 energy coupled proton transport, down electrochemical gradient 1/566 26/18722 0.550084431289037 0.693600179671634 STOML2 1 GO:0015986 ATP synthesis coupled proton transport 1/566 26/18722 0.550084431289037 0.693600179671634 STOML2 1 GO:0018027 peptidyl-lysine dimethylation 1/566 26/18722 0.550084431289037 0.693600179671634 PIH1D1 1 GO:0021680 cerebellar Purkinje cell layer development 1/566 26/18722 0.550084431289037 0.693600179671634 NAGLU 1 GO:0031167 rRNA methylation 1/566 26/18722 0.550084431289037 0.693600179671634 TRMT112 1 GO:0032682 negative regulation of chemokine production 1/566 26/18722 0.550084431289037 0.693600179671634 GSTP1 1 GO:0033598 mammary gland epithelial cell proliferation 1/566 26/18722 0.550084431289037 0.693600179671634 GPX1 1 GO:0034063 stress granule assembly 1/566 26/18722 0.550084431289037 0.693600179671634 CIRBP 1 GO:0045026 plasma membrane fusion 1/566 26/18722 0.550084431289037 0.693600179671634 FOLR1 1 GO:0046755 viral budding 1/566 26/18722 0.550084431289037 0.693600179671634 CHMP5 1 GO:0051016 barbed-end actin filament capping 1/566 26/18722 0.550084431289037 0.693600179671634 SCIN 1 GO:0051560 mitochondrial calcium ion homeostasis 1/566 26/18722 0.550084431289037 0.693600179671634 BNIP3 1 GO:0060219 camera-type eye photoreceptor cell differentiation 1/566 26/18722 0.550084431289037 0.693600179671634 NAGLU 1 GO:0060544 regulation of necroptotic process 1/566 26/18722 0.550084431289037 0.693600179671634 YBX3 1 GO:0070102 interleukin-6-mediated signaling pathway 1/566 26/18722 0.550084431289037 0.693600179671634 IL6ST 1 GO:0070920 regulation of production of small RNA involved in gene silencing by RNA 1/566 26/18722 0.550084431289037 0.693600179671634 EGFR 1 GO:0070977 bone maturation 1/566 26/18722 0.550084431289037 0.693600179671634 PLXNB1 1 GO:0071425 hematopoietic stem cell proliferation 1/566 26/18722 0.550084431289037 0.693600179671634 PDCD2 1 GO:0097066 response to thyroid hormone 1/566 26/18722 0.550084431289037 0.693600179671634 CTSB 1 GO:0097186 amelogenesis 1/566 26/18722 0.550084431289037 0.693600179671634 CSF3R 1 GO:0099637 neurotransmitter receptor transport 1/566 26/18722 0.550084431289037 0.693600179671634 CLSTN1 1 GO:1902656 calcium ion import into cytosol 1/566 26/18722 0.550084431289037 0.693600179671634 ATP2B4 1 GO:1903523 negative regulation of blood circulation 1/566 26/18722 0.550084431289037 0.693600179671634 SRI 1 GO:1904861 excitatory synapse assembly 1/566 26/18722 0.550084431289037 0.693600179671634 PLXNB2 1 GO:1905063 regulation of vascular associated smooth muscle cell differentiation 1/566 26/18722 0.550084431289037 0.693600179671634 ENG 1 GO:2000050 regulation of non-canonical Wnt signaling pathway 1/566 26/18722 0.550084431289037 0.693600179671634 ZNRF3 1 GO:2000108 positive regulation of leukocyte apoptotic process 1/566 26/18722 0.550084431289037 0.693600179671634 ANXA1 1 GO:0007498 mesoderm development 4/566 129/18722 0.55011281096598 0.693600179671634 RPL38/ITGB1/ITGB4/GJA1 4 GO:0042594 response to starvation 6/566 197/18722 0.550355275982382 0.693709424879265 HNRNPA1/AOC1/SLC2A1/SLC38A2/GABARAP/EIF2A 6 GO:0048709 oligodendrocyte differentiation 3/566 95/18722 0.551169391041874 0.69453895525571 GSTP1/DAG1/BNIP3 3 GO:0043954 cellular component maintenance 2/566 61/18722 0.554341269486992 0.697943249931021 APOE/IGF1R 2 GO:0043966 histone H3 acetylation 2/566 61/18722 0.554341269486992 0.697943249931021 POLE3/PIH1D1 2 GO:2000401 regulation of lymphocyte migration 2/566 61/18722 0.554341269486992 0.697943249931021 APP/AIF1 2 GO:0050864 regulation of B cell activation 6/566 198/18722 0.555324359284434 0.698983332636218 CD74/MIF/TYROBP/SLC39A10/MNDA/TFRC 6 GO:0015918 sterol transport 4/566 130/18722 0.556236389706236 0.699933410676134 APOC1/APOE/LRP1/ABCA1 4 GO:0016050 vesicle organization 9/566 300/18722 0.556740144632208 0.70036934837598 ANXA1/SERPINE2/SRGN/S100A10/CHMP5/ABCA1/TFG/GNAI3/RAB38 9 GO:0042113 B cell activation 10/566 334/18722 0.557498817213811 0.701125631140081 CD74/MIF/LGALS1/TYROBP/SLC25A5/HSPD1/ITGB1/SLC39A10/MNDA/TFRC 10 GO:0002718 regulation of cytokine production involved in immune response 3/566 96/18722 0.558289399686272 0.701401663042308 CD74/HLA-A/B2M 3 GO:0042632 cholesterol homeostasis 3/566 96/18722 0.558289399686272 0.701401663042308 APOE/ABCA1/LRP5 3 GO:0055017 cardiac muscle tissue growth 3/566 96/18722 0.558289399686272 0.701401663042308 CCNB1/CDK1/GJA1 3 GO:0006612 protein targeting to membrane 4/566 131/18722 0.562315143504875 0.701401663042308 SRP9/NACA/SRP19/SEC61A1 4 GO:0031124 mRNA 3'-end processing 2/566 62/18722 0.563194359292515 0.701401663042308 CCNB1/APP 2 GO:0046847 filopodium assembly 2/566 62/18722 0.563194359292515 0.701401663042308 NRP1/ITGB4 2 GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation 2/566 62/18722 0.563194359292515 0.701401663042308 LRP1/ENG 2 GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels 2/566 62/18722 0.563194359292515 0.701401663042308 DAG1/CLSTN1 2 GO:0002825 regulation of T-helper 1 type immune response 1/566 27/18722 0.563705110144963 0.701401663042308 ANXA1 1 GO:0003272 endocardial cushion formation 1/566 27/18722 0.563705110144963 0.701401663042308 ENG 1 GO:0009651 response to salt stress 1/566 27/18722 0.563705110144963 0.701401663042308 HSP90AB1 1 GO:0010561 negative regulation of glycoprotein biosynthetic process 1/566 27/18722 0.563705110144963 0.701401663042308 ITM2B 1 GO:0010758 regulation of macrophage chemotaxis 1/566 27/18722 0.563705110144963 0.701401663042308 MIF 1 GO:0010894 negative regulation of steroid biosynthetic process 1/566 27/18722 0.563705110144963 0.701401663042308 APOE 1 GO:0015813 L-glutamate transmembrane transport 1/566 27/18722 0.563705110144963 0.701401663042308 ITGB1 1 GO:0018195 peptidyl-arginine modification 1/566 27/18722 0.563705110144963 0.701401663042308 PARK7 1 GO:0018904 ether metabolic process 1/566 27/18722 0.563705110144963 0.701401663042308 TXN 1 GO:0034143 regulation of toll-like receptor 4 signaling pathway 1/566 27/18722 0.563705110144963 0.701401663042308 HMGB1 1 GO:0034453 microtubule anchoring 1/566 27/18722 0.563705110144963 0.701401663042308 DAG1 1 GO:0034698 response to gonadotropin 1/566 27/18722 0.563705110144963 0.701401663042308 CCNA2 1 GO:0035235 ionotropic glutamate receptor signaling pathway 1/566 27/18722 0.563705110144963 0.701401663042308 APP 1 GO:0036037 CD8-positive, alpha-beta T cell activation 1/566 27/18722 0.563705110144963 0.701401663042308 HLA-A 1 GO:0042745 circadian sleep/wake cycle 1/566 27/18722 0.563705110144963 0.701401663042308 ADRB1 1 GO:0045606 positive regulation of epidermal cell differentiation 1/566 27/18722 0.563705110144963 0.701401663042308 NME2 1 GO:0045830 positive regulation of isotype switching 1/566 27/18722 0.563705110144963 0.701401663042308 TFRC 1 GO:0048520 positive regulation of behavior 1/566 27/18722 0.563705110144963 0.701401663042308 GJA1 1 GO:0048873 homeostasis of number of cells within a tissue 1/566 27/18722 0.563705110144963 0.701401663042308 FH 1 GO:0051953 negative regulation of amine transport 1/566 27/18722 0.563705110144963 0.701401663042308 SLC43A2 1 GO:0060142 regulation of syncytium formation by plasma membrane fusion 1/566 27/18722 0.563705110144963 0.701401663042308 TYROBP 1 GO:0060333 interferon-gamma-mediated signaling pathway 1/566 27/18722 0.563705110144963 0.701401663042308 HSP90AB1 1 GO:0061437 renal system vasculature development 1/566 27/18722 0.563705110144963 0.701401663042308 NRP1 1 GO:0061440 kidney vasculature development 1/566 27/18722 0.563705110144963 0.701401663042308 NRP1 1 GO:0071624 positive regulation of granulocyte chemotaxis 1/566 27/18722 0.563705110144963 0.701401663042308 CD74 1 GO:0099625 ventricular cardiac muscle cell membrane repolarization 1/566 27/18722 0.563705110144963 0.701401663042308 AKAP9 1 GO:1900746 regulation of vascular endothelial growth factor signaling pathway 1/566 27/18722 0.563705110144963 0.701401663042308 SEMA6A 1 GO:1901018 positive regulation of potassium ion transmembrane transporter activity 1/566 27/18722 0.563705110144963 0.701401663042308 AKAP9 1 GO:1903203 regulation of oxidative stress-induced neuron death 1/566 27/18722 0.563705110144963 0.701401663042308 PARK7 1 GO:1903421 regulation of synaptic vesicle recycling 1/566 27/18722 0.563705110144963 0.701401663042308 CALM1 1 GO:0051056 regulation of small GTPase mediated signal transduction 9/566 302/18722 0.5647842408821 0.702455652113716 APOE/STMN1/ADGRG1/ITGAV/MET/NRP1/ITGB1/GABARAP/ABCA1 9 GO:0006721 terpenoid metabolic process 3/566 97/18722 0.565341105463487 0.702455652113716 LRP2/LRP1/EGFR 3 GO:0043255 regulation of carbohydrate biosynthetic process 3/566 97/18722 0.565341105463487 0.702455652113716 PPP1CA/IGF2/P2RY6 3 GO:0055092 sterol homeostasis 3/566 97/18722 0.565341105463487 0.702455652113716 APOE/ABCA1/LRP5 3 GO:0070167 regulation of biomineral tissue development 3/566 97/18722 0.565341105463487 0.702455652113716 FBN2/SRGN/ATP2B1 3 GO:0035264 multicellular organism growth 4/566 132/18722 0.568348302460684 0.705995156962881 LGMN/APP/IGF2/ADRB1 4 GO:0001947 heart looping 2/566 63/18722 0.571920609721666 0.710036406715242 ENG/FOLR1 2 GO:0099601 regulation of neurotransmitter receptor activity 2/566 63/18722 0.571920609721666 0.710036406715242 AKAP9/APP 2 GO:0002367 cytokine production involved in immune response 3/566 98/18722 0.572323620332049 0.710129492189564 CD74/HLA-A/B2M 3 GO:0000303 response to superoxide 1/566 28/18722 0.576914145055793 0.710129492189564 PRDX1 1 GO:0001945 lymph vessel development 1/566 28/18722 0.576914145055793 0.710129492189564 SVEP1 1 GO:0002313 mature B cell differentiation involved in immune response 1/566 28/18722 0.576914145055793 0.710129492189564 LGALS1 1 GO:0006516 glycoprotein catabolic process 1/566 28/18722 0.576914145055793 0.710129492189564 EDEM3 1 GO:0006829 zinc ion transport 1/566 28/18722 0.576914145055793 0.710129492189564 SLC39A10 1 GO:0007064 mitotic sister chromatid cohesion 1/566 28/18722 0.576914145055793 0.710129492189564 CDC20 1 GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway 1/566 28/18722 0.576914145055793 0.710129492189564 LRP1 1 GO:0007271 synaptic transmission, cholinergic 1/566 28/18722 0.576914145055793 0.710129492189564 APOE 1 GO:0009065 glutamine family amino acid catabolic process 1/566 28/18722 0.576914145055793 0.710129492189564 ATP2B4 1 GO:0009312 oligosaccharide biosynthetic process 1/566 28/18722 0.576914145055793 0.710129492189564 B4GALT1 1 GO:0010460 positive regulation of heart rate 1/566 28/18722 0.576914145055793 0.710129492189564 ADRB1 1 GO:0010464 regulation of mesenchymal cell proliferation 1/566 28/18722 0.576914145055793 0.710129492189564 LRP5 1 GO:0010884 positive regulation of lipid storage 1/566 28/18722 0.576914145055793 0.710129492189564 PLIN2 1 GO:0015740 C4-dicarboxylate transport 1/566 28/18722 0.576914145055793 0.710129492189564 SLC1A5 1 GO:0031440 regulation of mRNA 3'-end processing 1/566 28/18722 0.576914145055793 0.710129492189564 CCNB1 1 GO:0032438 melanosome organization 1/566 28/18722 0.576914145055793 0.710129492189564 RAB38 1 GO:0032958 inositol phosphate biosynthetic process 1/566 28/18722 0.576914145055793 0.710129492189564 P2RY6 1 GO:0038094 Fc-gamma receptor signaling pathway 1/566 28/18722 0.576914145055793 0.710129492189564 FCER1G 1 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway 1/566 28/18722 0.576914145055793 0.710129492189564 EGFR 1 GO:0042983 amyloid precursor protein biosynthetic process 1/566 28/18722 0.576914145055793 0.710129492189564 ITM2B 1 GO:0042984 regulation of amyloid precursor protein biosynthetic process 1/566 28/18722 0.576914145055793 0.710129492189564 ITM2B 1 GO:0045671 negative regulation of osteoclast differentiation 1/566 28/18722 0.576914145055793 0.710129492189564 FBN1 1 GO:0060765 regulation of androgen receptor signaling pathway 1/566 28/18722 0.576914145055793 0.710129492189564 PARK7 1 GO:0061082 myeloid leukocyte cytokine production 1/566 28/18722 0.576914145055793 0.710129492189564 CD74 1 GO:0062125 regulation of mitochondrial gene expression 1/566 28/18722 0.576914145055793 0.710129492189564 MALSU1 1 GO:0099623 regulation of cardiac muscle cell membrane repolarization 1/566 28/18722 0.576914145055793 0.710129492189564 AKAP9 1 GO:1902624 positive regulation of neutrophil migration 1/566 28/18722 0.576914145055793 0.710129492189564 CD74 1 GO:1903671 negative regulation of sprouting angiogenesis 1/566 28/18722 0.576914145055793 0.710129492189564 SEMA6A 1 GO:1904046 negative regulation of vascular endothelial growth factor production 1/566 28/18722 0.576914145055793 0.710129492189564 NUTF2 1 GO:2000241 regulation of reproductive process 5/566 168/18722 0.576940335410973 0.710129492189564 B4GALT1/CDC20/SERPINF1/GJA1/CALR 5 GO:0003300 cardiac muscle hypertrophy 3/566 99/18722 0.579236126653432 0.712364429795879 ATP2B4/IL6ST/GLRX3 3 GO:0010717 regulation of epithelial to mesenchymal transition 3/566 99/18722 0.579236126653432 0.712364429795879 ISL1/ENG/DAG1 3 GO:0110149 regulation of biomineralization 3/566 99/18722 0.579236126653432 0.712364429795879 FBN2/SRGN/ATP2B1 3 GO:0001885 endothelial cell development 2/566 64/18722 0.580519586083048 0.712761499515094 GPX1/MET 2 GO:0030104 water homeostasis 2/566 64/18722 0.580519586083048 0.712761499515094 STMN1/MET 2 GO:0030858 positive regulation of epithelial cell differentiation 2/566 64/18722 0.580519586083048 0.712761499515094 NME2/SERPINE1 2 GO:0046530 photoreceptor cell differentiation 2/566 64/18722 0.580519586083048 0.712761499515094 TUG1/NAGLU 2 GO:0046854 phosphatidylinositol phosphate biosynthetic process 2/566 64/18722 0.580519586083048 0.712761499515094 IMPA2/SMG1 2 GO:1900076 regulation of cellular response to insulin stimulus 2/566 64/18722 0.580519586083048 0.712761499515094 IGF2/ATP2B1 2 GO:0031214 biomineral tissue development 5/566 169/18722 0.582227116255269 0.714660910275284 FBN2/SPP1/SRGN/GPNMB/ATP2B1 5 GO:0006641 triglyceride metabolic process 3/566 100/18722 0.586077875135524 0.716553233973735 APOC1/APOE/GPX1 3 GO:0018205 peptidyl-lysine modification 11/566 376/18722 0.587140876839815 0.716553233973735 MORF4L2/ISL1/TRMT112/SUMO2/PARK7/POLE3/GCSH/HAT1/RUVBL1/DPY30/PIH1D1 11 GO:0030178 negative regulation of Wnt signaling pathway 5/566 170/18722 0.587478326008374 0.716553233973735 APOE/LRP1/ISL1/AMFR/ZNRF3 5 GO:0006487 protein N-linked glycosylation 2/566 65/18722 0.588990995606605 0.716553233973735 B4GALT1/MOGS 2 GO:0035418 protein localization to synapse 2/566 65/18722 0.588990995606605 0.716553233973735 DAG1/CLSTN1 2 GO:0038034 signal transduction in absence of ligand 2/566 65/18722 0.588990995606605 0.716553233973735 PPP1CA/ITGAV 2 GO:0045682 regulation of epidermis development 2/566 65/18722 0.588990995606605 0.716553233973735 KRT10/NME2 2 GO:0060389 pathway-restricted SMAD protein phosphorylation 2/566 65/18722 0.588990995606605 0.716553233973735 LRP1/ENG 2 GO:0090307 mitotic spindle assembly 2/566 65/18722 0.588990995606605 0.716553233973735 CHMP5/CDC20 2 GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand 2/566 65/18722 0.588990995606605 0.716553233973735 PPP1CA/ITGAV 2 GO:0000305 response to oxygen radical 1/566 29/18722 0.589723955363828 0.716553233973735 PRDX1 1 GO:0006656 phosphatidylcholine biosynthetic process 1/566 29/18722 0.589723955363828 0.716553233973735 RAB38 1 GO:0007143 female meiotic nuclear division 1/566 29/18722 0.589723955363828 0.716553233973735 CCNB2 1 GO:0009310 amine catabolic process 1/566 29/18722 0.589723955363828 0.716553233973735 ATP2B4 1 GO:0010592 positive regulation of lamellipodium assembly 1/566 29/18722 0.589723955363828 0.716553233973735 ARPC2 1 GO:0015701 bicarbonate transport 1/566 29/18722 0.589723955363828 0.716553233973735 SLC26A2 1 GO:0021522 spinal cord motor neuron differentiation 1/566 29/18722 0.589723955363828 0.716553233973735 ISL1 1 GO:0021591 ventricular system development 1/566 29/18722 0.589723955363828 0.716553233973735 SEMA6D 1 GO:0030970 retrograde protein transport, ER to cytosol 1/566 29/18722 0.589723955363828 0.716553233973735 HSP90B1 1 GO:0032366 intracellular sterol transport 1/566 29/18722 0.589723955363828 0.716553233973735 ABCA1 1 GO:0032367 intracellular cholesterol transport 1/566 29/18722 0.589723955363828 0.716553233973735 ABCA1 1 GO:0032372 negative regulation of sterol transport 1/566 29/18722 0.589723955363828 0.716553233973735 APOC1 1 GO:0032375 negative regulation of cholesterol transport 1/566 29/18722 0.589723955363828 0.716553233973735 APOC1 1 GO:0034067 protein localization to Golgi apparatus 1/566 29/18722 0.589723955363828 0.716553233973735 VPS13C 1 GO:0040018 positive regulation of multicellular organism growth 1/566 29/18722 0.589723955363828 0.716553233973735 IGF2 1 GO:0042759 long-chain fatty acid biosynthetic process 1/566 29/18722 0.589723955363828 0.716553233973735 GSTP1 1 GO:0043153 entrainment of circadian clock by photoperiod 1/566 29/18722 0.589723955363828 0.716553233973735 PPP1CA 1 GO:0048665 neuron fate specification 1/566 29/18722 0.589723955363828 0.716553233973735 ISL1 1 GO:0048753 pigment granule organization 1/566 29/18722 0.589723955363828 0.716553233973735 RAB38 1 GO:0051873 killing by host of symbiont cells 1/566 29/18722 0.589723955363828 0.716553233973735 GAPDH 1 GO:0051883 killing of cells in other organism involved in symbiotic interaction 1/566 29/18722 0.589723955363828 0.716553233973735 GAPDH 1 GO:0060441 epithelial tube branching involved in lung morphogenesis 1/566 29/18722 0.589723955363828 0.716553233973735 DAG1 1 GO:0060969 negative regulation of gene silencing 1/566 29/18722 0.589723955363828 0.716553233973735 NEAT1 1 GO:0090114 COPII-coated vesicle budding 1/566 29/18722 0.589723955363828 0.716553233973735 TFG 1 GO:1902430 negative regulation of amyloid-beta formation 1/566 29/18722 0.589723955363828 0.716553233973735 APOE 1 GO:1903513 endoplasmic reticulum to cytosol transport 1/566 29/18722 0.589723955363828 0.716553233973735 HSP90B1 1 GO:2001032 regulation of double-strand break repair via nonhomologous end joining 1/566 29/18722 0.589723955363828 0.716553233973735 DEK 1 GO:0098876 vesicle-mediated transport to the plasma membrane 4/566 136/18722 0.592010937714838 0.719135796645691 VPS29/CLSTN1/KRT18/MACF1 4 GO:0110148 biomineralization 5/566 171/18722 0.592693451547264 0.719563824918327 FBN2/SPP1/SRGN/GPNMB/ATP2B1 5 GO:0050830 defense response to Gram-positive bacterium 3/566 101/18722 0.592848182794345 0.719563824918327 LYZ/HMGB2/HLA-A 3 GO:0051963 regulation of synapse assembly 3/566 101/18722 0.592848182794345 0.719563824918327 CLSTN1/APP/UBE2V2 3 GO:0072678 T cell migration 2/566 66/18722 0.59733467928861 0.723746382960922 APP/AIF1 2 GO:1902476 chloride transmembrane transport 2/566 66/18722 0.59733467928861 0.723746382960922 SLC26A2/PCYOX1 2 GO:0008203 cholesterol metabolic process 4/566 137/18722 0.597805910477185 0.723746382960922 APOE/ABCA1/APP/LRP5 4 GO:0090090 negative regulation of canonical Wnt signaling pathway 4/566 137/18722 0.597805910477185 0.723746382960922 APOE/ISL1/AMFR/ZNRF3 4 GO:0048736 appendage development 5/566 172/18722 0.597872002389313 0.723746382960922 FBN2/ITGA6/ITGB4/LRP5/ZNRF3 5 GO:0060173 limb development 5/566 172/18722 0.597872002389313 0.723746382960922 FBN2/ITGA6/ITGB4/LRP5/ZNRF3 5 GO:0014897 striated muscle hypertrophy 3/566 102/18722 0.599546430936039 0.723746382960922 ATP2B4/IL6ST/GLRX3 3 GO:0062014 negative regulation of small molecule metabolic process 3/566 102/18722 0.599546430936039 0.723746382960922 APOC1/APOE/ATP2B4 3 GO:0003299 muscle hypertrophy in response to stress 1/566 30/18722 0.602146586362816 0.723746382960922 ATP2B4 1 GO:0006884 cell volume homeostasis 1/566 30/18722 0.602146586362816 0.723746382960922 NPM1 1 GO:0007176 regulation of epidermal growth factor-activated receptor activity 1/566 30/18722 0.602146586362816 0.723746382960922 APP 1 GO:0008209 androgen metabolic process 1/566 30/18722 0.602146586362816 0.723746382960922 SPP1 1 GO:0009072 aromatic amino acid family metabolic process 1/566 30/18722 0.602146586362816 0.723746382960922 PARK7 1 GO:0014887 cardiac muscle adaptation 1/566 30/18722 0.602146586362816 0.723746382960922 ATP2B4 1 GO:0014898 cardiac muscle hypertrophy in response to stress 1/566 30/18722 0.602146586362816 0.723746382960922 ATP2B4 1 GO:0017145 stem cell division 1/566 30/18722 0.602146586362816 0.723746382960922 CDK2AP2 1 GO:0030204 chondroitin sulfate metabolic process 1/566 30/18722 0.602146586362816 0.723746382960922 CHPF 1 GO:0031365 N-terminal protein amino acid modification 1/566 30/18722 0.602146586362816 0.723746382960922 NAA20 1 GO:0034694 response to prostaglandin 1/566 30/18722 0.602146586362816 0.723746382960922 P2RY6 1 GO:0036258 multivesicular body assembly 1/566 30/18722 0.602146586362816 0.723746382960922 CHMP5 1 GO:0043032 positive regulation of macrophage activation 1/566 30/18722 0.602146586362816 0.723746382960922 HSPD1 1 GO:0045939 negative regulation of steroid metabolic process 1/566 30/18722 0.602146586362816 0.723746382960922 APOE 1 GO:0048147 negative regulation of fibroblast proliferation 1/566 30/18722 0.602146586362816 0.723746382960922 GSTP1 1 GO:0048799 animal organ maturation 1/566 30/18722 0.602146586362816 0.723746382960922 PLXNB1 1 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway 1/566 30/18722 0.602146586362816 0.723746382960922 PHPT1 1 GO:0051125 regulation of actin nucleation 1/566 30/18722 0.602146586362816 0.723746382960922 SCIN 1 GO:0051491 positive regulation of filopodium assembly 1/566 30/18722 0.602146586362816 0.723746382960922 NRP1 1 GO:0051968 positive regulation of synaptic transmission, glutamatergic 1/566 30/18722 0.602146586362816 0.723746382960922 EGFR 1 GO:0060218 hematopoietic stem cell differentiation 1/566 30/18722 0.602146586362816 0.723746382960922 HSPA9 1 GO:0060603 mammary gland duct morphogenesis 1/566 30/18722 0.602146586362816 0.723746382960922 LRP5 1 GO:0061311 cell surface receptor signaling pathway involved in heart development 1/566 30/18722 0.602146586362816 0.723746382960922 GALNT11 1 GO:0061384 heart trabecula morphogenesis 1/566 30/18722 0.602146586362816 0.723746382960922 ENG 1 GO:0070168 negative regulation of biomineral tissue development 1/566 30/18722 0.602146586362816 0.723746382960922 SRGN 1 GO:1900101 regulation of endoplasmic reticulum unfolded protein response 1/566 30/18722 0.602146586362816 0.723746382960922 COPS5 1 GO:1903019 negative regulation of glycoprotein metabolic process 1/566 30/18722 0.602146586362816 0.723746382960922 ITM2B 1 GO:2000637 positive regulation of gene silencing by miRNA 1/566 30/18722 0.602146586362816 0.723746382960922 EGFR 1 GO:0006694 steroid biosynthetic process 5/566 173/18722 0.603013510407792 0.724592752587177 APOE/CGA/PRLR/SLC27A2/ASAH1 5 GO:0016358 dendrite development 7/566 243/18722 0.604664242750801 0.726269205131141 APOE/CFL1/NRP1/ITGB1/CDC20/APP/IQGAP1 7 GO:0009880 embryonic pattern specification 2/566 67/18722 0.605550604098561 0.726269205131141 SEMA3F/NRP1 2 GO:0032890 regulation of organic acid transport 2/566 67/18722 0.605550604098561 0.726269205131141 ITGB1/SLC43A2 2 GO:0042130 negative regulation of T cell proliferation 2/566 67/18722 0.605550604098561 0.726269205131141 HLA-DRB1/GPNMB 2 GO:0050435 amyloid-beta metabolic process 2/566 67/18722 0.605550604098561 0.726269205131141 APOE/MME 2 GO:0061180 mammary gland epithelium development 2/566 67/18722 0.605550604098561 0.726269205131141 GPX1/LRP5 2 GO:0061371 determination of heart left/right asymmetry 2/566 67/18722 0.605550604098561 0.726269205131141 ENG/FOLR1 2 GO:0007281 germ cell development 8/566 278/18722 0.606149563018487 0.726623054709933 RPS6/DYNLL1/HMGB2/CCNB1/LGR5/CCNB1IP1/HEXB/PAQR7 8 GO:0030004 cellular monovalent inorganic cation homeostasis 3/566 103/18722 0.606172063160982 0.726623054709933 GRN/ATP6AP1/RAB38 3 GO:0016311 dephosphorylation 12/566 417/18722 0.610346041697957 0.729559883634693 CALM1/HSP90AB1/PPIA/PTPRF/PHPT1/PPP1CA/PPM1G/IMPA2/PPP4C/HSP90B1/PLPP3/SLC39A10 12 GO:0046394 carboxylic acid biosynthetic process 9/566 314/18722 0.611669537166759 0.729559883634693 CD74/MIF/APOC1/ANXA1/ATP2B4/GSTP1/PTGES3/PARK7/SLC27A2 9 GO:0006892 post-Golgi vesicle-mediated transport 3/566 104/18722 0.612724583391684 0.729559883634693 KRT18/MACF1/VPS13C 3 GO:0060419 heart growth 3/566 104/18722 0.612724583391684 0.729559883634693 CCNB1/CDK1/GJA1 3 GO:0032922 circadian regulation of gene expression 2/566 68/18722 0.613638855533604 0.729559883634693 PPP1CA/ZFHX3 2 GO:0034394 protein localization to cell surface 2/566 68/18722 0.613638855533604 0.729559883634693 HSP90AB1/TYROBP 2 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 2/566 68/18722 0.613638855533604 0.729559883634693 IL6ST/ISL1 2 GO:0042698 ovulation cycle 2/566 68/18722 0.613638855533604 0.729559883634693 EGFR/SERPINF1 2 GO:0051148 negative regulation of muscle cell differentiation 2/566 68/18722 0.613638855533604 0.729559883634693 YBX1/IGF2 2 GO:1901016 regulation of potassium ion transmembrane transporter activity 2/566 68/18722 0.613638855533604 0.729559883634693 ITGB1/AKAP9 2 GO:1901607 alpha-amino acid biosynthetic process 2/566 68/18722 0.613638855533604 0.729559883634693 ATP2B4/PARK7 2 GO:1902305 regulation of sodium ion transmembrane transport 2/566 68/18722 0.613638855533604 0.729559883634693 ATP2B4/GLRX 2 GO:0001782 B cell homeostasis 1/566 31/18722 0.614193720544212 0.729559883634693 CD74 1 GO:0030201 heparan sulfate proteoglycan metabolic process 1/566 31/18722 0.614193720544212 0.729559883634693 HS6ST2 1 GO:0030212 hyaluronan metabolic process 1/566 31/18722 0.614193720544212 0.729559883634693 ITIH5 1 GO:0032509 endosome transport via multivesicular body sorting pathway 1/566 31/18722 0.614193720544212 0.729559883634693 CHMP5 1 GO:0034472 snRNA 3'-end processing 1/566 31/18722 0.614193720544212 0.729559883634693 EXOSC9 1 GO:0036257 multivesicular body organization 1/566 31/18722 0.614193720544212 0.729559883634693 CHMP5 1 GO:0036475 neuron death in response to oxidative stress 1/566 31/18722 0.614193720544212 0.729559883634693 PARK7 1 GO:0042133 neurotransmitter metabolic process 1/566 31/18722 0.614193720544212 0.729559883634693 SLC6A4 1 GO:0048384 retinoic acid receptor signaling pathway 1/566 31/18722 0.614193720544212 0.729559883634693 CALR 1 GO:0050482 arachidonic acid secretion 1/566 31/18722 0.614193720544212 0.729559883634693 ANXA1 1 GO:0051569 regulation of histone H3-K4 methylation 1/566 31/18722 0.614193720544212 0.729559883634693 PIH1D1 1 GO:0055022 negative regulation of cardiac muscle tissue growth 1/566 31/18722 0.614193720544212 0.729559883634693 GJA1 1 GO:0060148 positive regulation of posttranscriptional gene silencing 1/566 31/18722 0.614193720544212 0.729559883634693 EGFR 1 GO:0060390 regulation of SMAD protein signal transduction 1/566 31/18722 0.614193720544212 0.729559883634693 LRP1 1 GO:0061117 negative regulation of heart growth 1/566 31/18722 0.614193720544212 0.729559883634693 GJA1 1 GO:0070528 protein kinase C signaling 1/566 31/18722 0.614193720544212 0.729559883634693 ADGRG1 1 GO:0071168 protein localization to chromatin 1/566 31/18722 0.614193720544212 0.729559883634693 PIH1D1 1 GO:0110150 negative regulation of biomineralization 1/566 31/18722 0.614193720544212 0.729559883634693 SRGN 1 GO:1900027 regulation of ruffle assembly 1/566 31/18722 0.614193720544212 0.729559883634693 PFN1 1 GO:1903963 arachidonate transport 1/566 31/18722 0.614193720544212 0.729559883634693 ANXA1 1 GO:1905144 response to acetylcholine 1/566 31/18722 0.614193720544212 0.729559883634693 ATP2B4 1 GO:1905145 cellular response to acetylcholine 1/566 31/18722 0.614193720544212 0.729559883634693 ATP2B4 1 GO:0030177 positive regulation of Wnt signaling pathway 4/566 140/18722 0.614892284008543 0.730194838198462 EGFR/LGR5/MACF1/RUVBL1 4 GO:0042180 cellular ketone metabolic process 6/566 211/18722 0.617439822805823 0.733024557635073 CD74/APOC1/TPI1/ANXA1/ATP2B4/PARK7 6 GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 3/566 105/18722 0.619203553925994 0.734762438548095 PFN1/ARPC2/NRP1 3 GO:0016053 organic acid biosynthetic process 9/566 316/18722 0.619233753241791 0.734762438548095 CD74/MIF/APOC1/ANXA1/ATP2B4/GSTP1/PTGES3/PARK7/SLC27A2 9 GO:0003143 embryonic heart tube morphogenesis 2/566 69/18722 0.621599630506659 0.736784226574986 ENG/FOLR1 2 GO:0034605 cellular response to heat 2/566 69/18722 0.621599630506659 0.736784226574986 HSP90AB1/HSPD1 2 GO:0050805 negative regulation of synaptic transmission 2/566 69/18722 0.621599630506659 0.736784226574986 SLC6A4/EIF4A3 2 GO:0051966 regulation of synaptic transmission, glutamatergic 2/566 69/18722 0.621599630506659 0.736784226574986 SERPINE2/EGFR 2 GO:0051302 regulation of cell division 5/566 177/18722 0.623200517625383 0.737924527867659 YBX1/CALM1/CDK2AP2/IGF2/TXNIP 5 GO:0009100 glycoprotein metabolic process 11/566 387/18722 0.625343114307654 0.737924527867659 ITM2B/CHPF/PARK7/AMFR/GANAB/B4GALT1/GALNT11/HS6ST2/MOGS/EDEM3/B3GNT3 11 GO:0002062 chondrocyte differentiation 3/566 106/18722 0.625608593517001 0.737924527867659 EFEMP1/SCIN/GLG1 3 GO:0035821 modulation of process of other organism 3/566 106/18722 0.625608593517001 0.737924527867659 APOE/CFL1/DAG1 3 GO:0090263 positive regulation of canonical Wnt signaling pathway 3/566 106/18722 0.625608593517001 0.737924527867659 EGFR/LGR5/RUVBL1 3 GO:0006335 DNA replication-dependent nucleosome assembly 1/566 32/18722 0.625876688505903 0.737924527867659 HAT1 1 GO:0008156 negative regulation of DNA replication 1/566 32/18722 0.625876688505903 0.737924527867659 GMNN 1 GO:0019835 cytolysis 1/566 32/18722 0.625876688505903 0.737924527867659 LYZ 1 GO:0019934 cGMP-mediated signaling 1/566 32/18722 0.625876688505903 0.737924527867659 APOE 1 GO:0030431 sleep 1/566 32/18722 0.625876688505903 0.737924527867659 ADRB1 1 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway 1/566 32/18722 0.625876688505903 0.737924527867659 HSP90AB1 1 GO:0034723 DNA replication-dependent nucleosome organization 1/566 32/18722 0.625876688505903 0.737924527867659 HAT1 1 GO:0045879 negative regulation of smoothened signaling pathway 1/566 32/18722 0.625876688505903 0.737924527867659 SERPINE2 1 GO:0046475 glycerophospholipid catabolic process 1/566 32/18722 0.625876688505903 0.737924527867659 APOC1 1 GO:0060317 cardiac epithelial to mesenchymal transition 1/566 32/18722 0.625876688505903 0.737924527867659 ENG 1 GO:0061037 negative regulation of cartilage development 1/566 32/18722 0.625876688505903 0.737924527867659 EFEMP1 1 GO:0090140 regulation of mitochondrial fission 1/566 32/18722 0.625876688505903 0.737924527867659 BNIP3 1 GO:1901889 negative regulation of cell junction assembly 1/566 32/18722 0.625876688505903 0.737924527867659 LRP1 1 GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 1/566 32/18722 0.625876688505903 0.737924527867659 PARK7 1 GO:1903846 positive regulation of cellular response to transforming growth factor beta stimulus 1/566 32/18722 0.625876688505903 0.737924527867659 HSP90AB1 1 GO:0043583 ear development 6/566 213/18722 0.626553122706594 0.738526476645422 LGR5/SPARC/RPL38/CCNA2/NAGLU/LRP10 6 GO:0006066 alcohol metabolic process 10/566 353/18722 0.627613331979431 0.739580347795772 APOE/TPI1/PARK7/IMPA2/ABCA1/APP/PLPP3/LRP5/ASAH1/P2RY6 10 GO:0006109 regulation of carbohydrate metabolic process 5/566 178/18722 0.628150551266347 0.740017532214284 HMGB1/PPP1CA/APP/IGF2/P2RY6 5 GO:0030010 establishment of cell polarity 4/566 143/18722 0.631521144864298 0.743791570617952 HSP90AB1/MAD2L1/ITGB1/GJA1 4 GO:0071868 cellular response to monoamine stimulus 3/566 107/18722 0.631939375480853 0.743890560454986 ATP2B4/APP/GNAI3 3 GO:0071870 cellular response to catecholamine stimulus 3/566 107/18722 0.631939375480853 0.743890560454986 ATP2B4/APP/GNAI3 3 GO:0006399 tRNA metabolic process 5/566 179/18722 0.633061185986581 0.744969340042834 LSM6/SSB/TRMT112/TPRKB/EXOSC9 5 GO:0048562 embryonic organ morphogenesis 8/566 285/18722 0.63398268375594 0.744969340042834 FBN2/FBN1/EIF4A3/RPL38/ENG/EFEMP1/NAGLU/FOLR1 8 GO:0031644 regulation of nervous system process 4/566 144/18722 0.636960579139086 0.744969340042834 EIF4A3/DAG1/AKAP9/APP 4 GO:0000281 mitotic cytokinesis 2/566 71/18722 0.637140055356059 0.744969340042834 STMN1/CHMP5 2 GO:0008344 adult locomotory behavior 2/566 71/18722 0.637140055356059 0.744969340042834 PARK7/APP 2 GO:0001881 receptor recycling 1/566 33/18722 0.637206479533493 0.744969340042834 CHMP5 1 GO:0001975 response to amphetamine 1/566 33/18722 0.637206479533493 0.744969340042834 CALM1 1 GO:0002335 mature B cell differentiation 1/566 33/18722 0.637206479533493 0.744969340042834 LGALS1 1 GO:0002431 Fc receptor mediated stimulatory signaling pathway 1/566 33/18722 0.637206479533493 0.744969340042834 FCER1G 1 GO:0006536 glutamate metabolic process 1/566 33/18722 0.637206479533493 0.744969340042834 MTHFS 1 GO:0006891 intra-Golgi vesicle-mediated transport 1/566 33/18722 0.637206479533493 0.744969340042834 COPZ1 1 GO:0009648 photoperiodism 1/566 33/18722 0.637206479533493 0.744969340042834 PPP1CA 1 GO:0010737 protein kinase A signaling 1/566 33/18722 0.637206479533493 0.744969340042834 MIF 1 GO:0010984 regulation of lipoprotein particle clearance 1/566 33/18722 0.637206479533493 0.744969340042834 APOC1 1 GO:0021696 cerebellar cortex morphogenesis 1/566 33/18722 0.637206479533493 0.744969340042834 SERPINE2 1 GO:0035025 positive regulation of Rho protein signal transduction 1/566 33/18722 0.637206479533493 0.744969340042834 ADGRG1 1 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 1/566 33/18722 0.637206479533493 0.744969340042834 FLT1 1 GO:0045648 positive regulation of erythrocyte differentiation 1/566 33/18722 0.637206479533493 0.744969340042834 HMGB2 1 GO:0045920 negative regulation of exocytosis 1/566 33/18722 0.637206479533493 0.744969340042834 ANXA1 1 GO:0050901 leukocyte tethering or rolling 1/566 33/18722 0.637206479533493 0.744969340042834 ITGB1 1 GO:0050974 detection of mechanical stimulus involved in sensory perception 1/566 33/18722 0.637206479533493 0.744969340042834 SERPINE2 1 GO:0071763 nuclear membrane organization 1/566 33/18722 0.637206479533493 0.744969340042834 VRK1 1 GO:0099174 regulation of presynapse organization 1/566 33/18722 0.637206479533493 0.744969340042834 APP 1 GO:1902275 regulation of chromatin organization 1/566 33/18722 0.637206479533493 0.744969340042834 MKI67 1 GO:1902992 negative regulation of amyloid precursor protein catabolic process 1/566 33/18722 0.637206479533493 0.744969340042834 APOE 1 GO:1905606 regulation of presynapse assembly 1/566 33/18722 0.637206479533493 0.744969340042834 APP 1 GO:0007173 epidermal growth factor receptor signaling pathway 3/566 108/18722 0.638195625833603 0.74592988348942 EGFR/EFEMP1/IQGAP1 3 GO:0006479 protein methylation 5/566 181/18722 0.642762997853486 0.750874013761144 TRMT112/SNRPB/SNRPD3/DPY30/PIH1D1 5 GO:0008213 protein alkylation 5/566 181/18722 0.642762997853486 0.750874013761144 TRMT112/SNRPB/SNRPD3/DPY30/PIH1D1 5 GO:0006821 chloride transport 3/566 109/18722 0.644377121458061 0.751108428760629 SLC26A2/PCYOX1/P2RY6 3 GO:0030032 lamellipodium assembly 2/566 72/18722 0.644720596539312 0.751108428760629 ARPC2/ITGB1 2 GO:0050709 negative regulation of protein secretion 2/566 72/18722 0.644720596539312 0.751108428760629 APOE/ANXA1 2 GO:0051057 positive regulation of small GTPase mediated signal transduction 2/566 72/18722 0.644720596539312 0.751108428760629 ADGRG1/ITGAV 2 GO:0051260 protein homooligomerization 5/566 182/18722 0.647553593892176 0.751108428760629 MIF/ALDOA/B2M/TK1/SLC1A5 5 GO:0010675 regulation of cellular carbohydrate metabolic process 4/566 146/18722 0.647682211765739 0.751108428760629 HMGB1/PPP1CA/IGF2/P2RY6 4 GO:0000038 very long-chain fatty acid metabolic process 1/566 34/18722 0.648193751863957 0.751108428760629 SLC27A2 1 GO:0000096 sulfur amino acid metabolic process 1/566 34/18722 0.648193751863957 0.751108428760629 SMS 1 GO:0002446 neutrophil mediated immunity 1/566 34/18722 0.648193751863957 0.751108428760629 ANXA3 1 GO:0006270 DNA replication initiation 1/566 34/18722 0.648193751863957 0.751108428760629 CCNE1 1 GO:0007095 mitotic G2 DNA damage checkpoint signaling 1/566 34/18722 0.648193751863957 0.751108428760629 CDK1 1 GO:0007616 long-term memory 1/566 34/18722 0.648193751863957 0.751108428760629 APOE 1 GO:0009649 entrainment of circadian clock 1/566 34/18722 0.648193751863957 0.751108428760629 PPP1CA 1 GO:0010661 positive regulation of muscle cell apoptotic process 1/566 34/18722 0.648193751863957 0.751108428760629 BNIP3 1 GO:0014072 response to isoquinoline alkaloid 1/566 34/18722 0.648193751863957 0.751108428760629 AIF1 1 GO:0019076 viral release from host cell 1/566 34/18722 0.648193751863957 0.751108428760629 PPIA 1 GO:0035590 purinergic nucleotide receptor signaling pathway 1/566 34/18722 0.648193751863957 0.751108428760629 P2RY6 1 GO:0035890 exit from host 1/566 34/18722 0.648193751863957 0.751108428760629 PPIA 1 GO:0035891 exit from host cell 1/566 34/18722 0.648193751863957 0.751108428760629 PPIA 1 GO:0043276 anoikis 1/566 34/18722 0.648193751863957 0.751108428760629 ITGB1 1 GO:0043278 response to morphine 1/566 34/18722 0.648193751863957 0.751108428760629 AIF1 1 GO:0044319 wound healing, spreading of cells 1/566 34/18722 0.648193751863957 0.751108428760629 PDCD10 1 GO:0048741 skeletal muscle fiber development 1/566 34/18722 0.648193751863957 0.751108428760629 GPX1 1 GO:0048854 brain morphogenesis 1/566 34/18722 0.648193751863957 0.751108428760629 SLC6A4 1 GO:0050931 pigment cell differentiation 1/566 34/18722 0.648193751863957 0.751108428760629 RAB38 1 GO:0070050 neuron cellular homeostasis 1/566 34/18722 0.648193751863957 0.751108428760629 ATP2B1 1 GO:0070884 regulation of calcineurin-NFAT signaling cascade 1/566 34/18722 0.648193751863957 0.751108428760629 ATP2B4 1 GO:0086019 cell-cell signaling involved in cardiac conduction 1/566 34/18722 0.648193751863957 0.751108428760629 GJA1 1 GO:0090075 relaxation of muscle 1/566 34/18722 0.648193751863957 0.751108428760629 SRI 1 GO:0090505 epiboly involved in wound healing 1/566 34/18722 0.648193751863957 0.751108428760629 PDCD10 1 GO:2000352 negative regulation of endothelial cell apoptotic process 1/566 34/18722 0.648193751863957 0.751108428760629 SERPINE1 1 GO:0009063 cellular amino acid catabolic process 3/566 110/18722 0.650483688301525 0.753173831032091 ATP2B4/GCSH/ECHS1 3 GO:0009408 response to heat 3/566 110/18722 0.650483688301525 0.753173831032091 HSP90AB1/DNAJA1/HSPD1 3 GO:0018958 phenol-containing compound metabolic process 3/566 110/18722 0.650483688301525 0.753173831032091 PARK7/CGA/CTSB 3 GO:0050848 regulation of calcium-mediated signaling 2/566 73/18722 0.652175431780413 0.754740062980608 CALM1/ATP2B4 2 GO:0051298 centrosome duplication 2/566 73/18722 0.652175431780413 0.754740062980608 NPM1/CHMP5 2 GO:1902652 secondary alcohol metabolic process 4/566 147/18722 0.652963862091136 0.755456110714589 APOE/ABCA1/APP/LRP5 4 GO:0071375 cellular response to peptide hormone stimulus 8/566 290/18722 0.653182766259615 0.755513035954224 FBN1/PKM/CYBA/GSTP1/CCNA2/IGF2/ATP2B1/IGF1R 8 GO:0006805 xenobiotic metabolic process 3/566 111/18722 0.656515199605137 0.757735739457142 GSTP1/GSTO1/NUDT15 3 GO:0071867 response to monoamine 3/566 111/18722 0.656515199605137 0.757735739457142 ATP2B4/APP/GNAI3 3 GO:0071869 response to catecholamine 3/566 111/18722 0.656515199605137 0.757735739457142 ATP2B4/APP/GNAI3 3 GO:0044272 sulfur compound biosynthetic process 4/566 148/18722 0.658192417495193 0.757735739457142 GSTP1/CHPF/SLC26A2/B3GNT3 4 GO:0000460 maturation of 5.8S rRNA 1/566 35/18722 0.658848842641194 0.757735739457142 EXOSC9 1 GO:0000731 DNA synthesis involved in DNA repair 1/566 35/18722 0.658848842641194 0.757735739457142 RFC3 1 GO:0015695 organic cation transport 1/566 35/18722 0.658848842641194 0.757735739457142 SLC38A2 1 GO:0021955 central nervous system neuron axonogenesis 1/566 35/18722 0.658848842641194 0.757735739457142 HSP90AB1 1 GO:0032814 regulation of natural killer cell activation 1/566 35/18722 0.658848842641194 0.757735739457142 TYROBP 1 GO:0033146 regulation of intracellular estrogen receptor signaling pathway 1/566 35/18722 0.658848842641194 0.757735739457142 ISL1 1 GO:0045922 negative regulation of fatty acid metabolic process 1/566 35/18722 0.658848842641194 0.757735739457142 APOC1 1 GO:0046471 phosphatidylglycerol metabolic process 1/566 35/18722 0.658848842641194 0.757735739457142 STOML2 1 GO:0046640 regulation of alpha-beta T cell proliferation 1/566 35/18722 0.658848842641194 0.757735739457142 HLA-A 1 GO:0048821 erythrocyte development 1/566 35/18722 0.658848842641194 0.757735739457142 RPS6 1 GO:0050654 chondroitin sulfate proteoglycan metabolic process 1/566 35/18722 0.658848842641194 0.757735739457142 CHPF 1 GO:0060236 regulation of mitotic spindle organization 1/566 35/18722 0.658848842641194 0.757735739457142 CHMP5 1 GO:0070536 protein K63-linked deubiquitination 1/566 35/18722 0.658848842641194 0.757735739457142 PSMD14 1 GO:0090181 regulation of cholesterol metabolic process 1/566 35/18722 0.658848842641194 0.757735739457142 APOE 1 GO:0090504 epiboly 1/566 35/18722 0.658848842641194 0.757735739457142 PDCD10 1 GO:0106056 regulation of calcineurin-mediated signaling 1/566 35/18722 0.658848842641194 0.757735739457142 ATP2B4 1 GO:1905207 regulation of cardiocyte differentiation 1/566 35/18722 0.658848842641194 0.757735739457142 EGFR 1 GO:1905898 positive regulation of response to endoplasmic reticulum stress 1/566 35/18722 0.658848842641194 0.757735739457142 TMEM259 1 GO:0030968 endoplasmic reticulum unfolded protein response 2/566 74/18722 0.659505219168087 0.757903261676903 AMFR/COPS5 2 GO:0046470 phosphatidylcholine metabolic process 2/566 74/18722 0.659505219168087 0.757903261676903 APOC1/RAB38 2 GO:0120192 tight junction assembly 2/566 74/18722 0.659505219168087 0.757903261676903 ACTG1/GJA1 2 GO:0034121 regulation of toll-like receptor signaling pathway 2/566 75/18722 0.66671069183164 0.765788441701357 HMGB1/CYBA 2 GO:0051453 regulation of intracellular pH 2/566 75/18722 0.66671069183164 0.765788441701357 GRN/RAB38 2 GO:0006699 bile acid biosynthetic process 1/566 36/18722 0.669181777572702 0.766254442837877 SLC27A2 1 GO:0010762 regulation of fibroblast migration 1/566 36/18722 0.669181777572702 0.766254442837877 ITGB1 1 GO:0016180 snRNA processing 1/566 36/18722 0.669181777572702 0.766254442837877 EXOSC9 1 GO:0017004 cytochrome complex assembly 1/566 36/18722 0.669181777572702 0.766254442837877 CYBA 1 GO:0044060 regulation of endocrine process 1/566 36/18722 0.669181777572702 0.766254442837877 GJA1 1 GO:0044743 protein transmembrane import into intracellular organelle 1/566 36/18722 0.669181777572702 0.766254442837877 HSPD1 1 GO:0045191 regulation of isotype switching 1/566 36/18722 0.669181777572702 0.766254442837877 TFRC 1 GO:0045738 negative regulation of DNA repair 1/566 36/18722 0.669181777572702 0.766254442837877 RPS3 1 GO:0051354 negative regulation of oxidoreductase activity 1/566 36/18722 0.669181777572702 0.766254442837877 ATP2B4 1 GO:0060251 regulation of glial cell proliferation 1/566 36/18722 0.669181777572702 0.766254442837877 EGFR 1 GO:0060338 regulation of type I interferon-mediated signaling pathway 1/566 36/18722 0.669181777572702 0.766254442837877 HSP90AB1 1 GO:0070306 lens fiber cell differentiation 1/566 36/18722 0.669181777572702 0.766254442837877 VIM 1 GO:0019221 cytokine-mediated signaling pathway 13/566 472/18722 0.673575187459363 0.770939319030987 CD74/HSP90AB1/CSF3R/FCER1G/IL6ST/GSTP1/ZC3H15/IFITM2/KRT8/TMSB4X/KRT18/PRLR/P4HB 13 GO:0008652 cellular amino acid biosynthetic process 2/566 76/18722 0.673792652818862 0.770939319030987 ATP2B4/PARK7 2 GO:0032720 negative regulation of tumor necrosis factor production 2/566 76/18722 0.673792652818862 0.770939319030987 GSTP1/GPNMB 2 GO:0002244 hematopoietic progenitor cell differentiation 3/566 114/18722 0.674158805820947 0.77096198394936 FLT1/HSPA9/PDCD2 3 GO:0051261 protein depolymerization 3/566 114/18722 0.674158805820947 0.77096198394936 STMN1/CFL1/SCIN 3 GO:0048839 inner ear development 5/566 188/18722 0.675437515300481 0.77222594199223 LGR5/SPARC/CCNA2/NAGLU/LRP10 5 GO:0016125 sterol metabolic process 4/566 152/18722 0.678572021090643 0.772957196288163 APOE/ABCA1/APP/LRP5 4 GO:0050871 positive regulation of B cell activation 4/566 152/18722 0.678572021090643 0.772957196288163 CD74/MIF/SLC39A10/TFRC 4 GO:0003016 respiratory system process 1/566 37/18722 0.679202280296337 0.772957196288163 GAA 1 GO:0006623 protein targeting to vacuole 1/566 37/18722 0.679202280296337 0.772957196288163 VPS13C 1 GO:0007340 acrosome reaction 1/566 37/18722 0.679202280296337 0.772957196288163 B4GALT1 1 GO:0014904 myotube cell development 1/566 37/18722 0.679202280296337 0.772957196288163 GPX1 1 GO:0030513 positive regulation of BMP signaling pathway 1/566 37/18722 0.679202280296337 0.772957196288163 ENG 1 GO:0031646 positive regulation of nervous system process 1/566 37/18722 0.679202280296337 0.772957196288163 DAG1 1 GO:0043368 positive T cell selection 1/566 37/18722 0.679202280296337 0.772957196288163 CD74 1 GO:0045616 regulation of keratinocyte differentiation 1/566 37/18722 0.679202280296337 0.772957196288163 NME2 1 GO:0051567 histone H3-K9 methylation 1/566 37/18722 0.679202280296337 0.772957196288163 PIH1D1 1 GO:0051954 positive regulation of amine transport 1/566 37/18722 0.679202280296337 0.772957196288163 ITGB1 1 GO:0060306 regulation of membrane repolarization 1/566 37/18722 0.679202280296337 0.772957196288163 AKAP9 1 GO:0071985 multivesicular body sorting pathway 1/566 37/18722 0.679202280296337 0.772957196288163 CHMP5 1 GO:0072529 pyrimidine-containing compound catabolic process 1/566 37/18722 0.679202280296337 0.772957196288163 DUT 1 GO:0090218 positive regulation of lipid kinase activity 1/566 37/18722 0.679202280296337 0.772957196288163 FLT1 1 GO:1902745 positive regulation of lamellipodium organization 1/566 37/18722 0.679202280296337 0.772957196288163 ARPC2 1 GO:1905332 positive regulation of morphogenesis of an epithelium 1/566 37/18722 0.679202280296337 0.772957196288163 GJA1 1 GO:0000077 DNA damage checkpoint signaling 3/566 115/18722 0.679889713104112 0.773146616280845 RPL26/CDK1/TRIAP1 3 GO:0030278 regulation of ossification 3/566 115/18722 0.679889713104112 0.773146616280845 FBN2/SRGN/ATP2B1 3 GO:0034968 histone lysine methylation 3/566 115/18722 0.679889713104112 0.773146616280845 TRMT112/DPY30/PIH1D1 3 GO:0051216 cartilage development 5/566 190/18722 0.684400031416786 0.778076848791504 TYMS/ITGB8/EFEMP1/SCIN/GLG1 5 GO:0006720 isoprenoid metabolic process 3/566 116/18722 0.68554558077738 0.779180220990782 LRP2/LRP1/EGFR 3 GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway 2/566 78/18722 0.687589572486782 0.780905300181417 PSAP/GNAI3 2 GO:0035050 embryonic heart tube development 2/566 78/18722 0.687589572486782 0.780905300181417 ENG/FOLR1 2 GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production 2/566 78/18722 0.687589572486782 0.780905300181417 GSTP1/GPNMB 2 GO:0010613 positive regulation of cardiac muscle hypertrophy 1/566 38/18722 0.688919781465846 0.781021356528125 IL6ST 1 GO:0030279 negative regulation of ossification 1/566 38/18722 0.688919781465846 0.781021356528125 SRGN 1 GO:0035886 vascular associated smooth muscle cell differentiation 1/566 38/18722 0.688919781465846 0.781021356528125 ENG 1 GO:0046633 alpha-beta T cell proliferation 1/566 38/18722 0.688919781465846 0.781021356528125 HLA-A 1 GO:0048246 macrophage chemotaxis 1/566 38/18722 0.688919781465846 0.781021356528125 MIF 1 GO:0048713 regulation of oligodendrocyte differentiation 1/566 38/18722 0.688919781465846 0.781021356528125 DAG1 1 GO:0099622 cardiac muscle cell membrane repolarization 1/566 38/18722 0.688919781465846 0.781021356528125 AKAP9 1 GO:0032868 response to insulin 7/566 264/18722 0.689781268619688 0.781798932763455 PKM/GSTP1/SLC2A1/IGF2/VPS13C/ATP2B1/IGF1R 7 GO:0051147 regulation of muscle cell differentiation 4/566 155/18722 0.693291866211291 0.785577854001696 YBX1/MORF4L2/ENG/IGF2 4 GO:0006029 proteoglycan metabolic process 2/566 79/18722 0.694306444060665 0.786327216728079 CHPF/HS6ST2 2 GO:1901184 regulation of ERBB signaling pathway 2/566 79/18722 0.694306444060665 0.786327216728079 EGFR/LGMN 2 GO:0001941 postsynaptic membrane organization 1/566 39/18722 0.698343427563594 0.788292327462759 APOE 1 GO:0010463 mesenchymal cell proliferation 1/566 39/18722 0.698343427563594 0.788292327462759 LRP5 1 GO:0014742 positive regulation of muscle hypertrophy 1/566 39/18722 0.698343427563594 0.788292327462759 IL6ST 1 GO:0021587 cerebellum morphogenesis 1/566 39/18722 0.698343427563594 0.788292327462759 SERPINE2 1 GO:0031507 heterochromatin assembly 1/566 39/18722 0.698343427563594 0.788292327462759 POLE3 1 GO:0032506 cytokinetic process 1/566 39/18722 0.698343427563594 0.788292327462759 CHMP5 1 GO:0036297 interstrand cross-link repair 1/566 39/18722 0.698343427563594 0.788292327462759 RAD51 1 GO:0042417 dopamine metabolic process 1/566 39/18722 0.698343427563594 0.788292327462759 PARK7 1 GO:0045823 positive regulation of heart contraction 1/566 39/18722 0.698343427563594 0.788292327462759 ADRB1 1 GO:0051154 negative regulation of striated muscle cell differentiation 1/566 39/18722 0.698343427563594 0.788292327462759 YBX1 1 GO:0090207 regulation of triglyceride metabolic process 1/566 39/18722 0.698343427563594 0.788292327462759 APOE 1 GO:0090224 regulation of spindle organization 1/566 39/18722 0.698343427563594 0.788292327462759 CHMP5 1 GO:1902742 apoptotic process involved in development 1/566 39/18722 0.698343427563594 0.788292327462759 LRP5 1 GO:0010906 regulation of glucose metabolic process 3/566 119/18722 0.702064340411892 0.792291620662546 HMGB1/PPP1CA/IGF2 3 GO:0001837 epithelial to mesenchymal transition 4/566 157/18722 0.702835148710189 0.792960487090157 HNRNPAB/ISL1/ENG/DAG1 4 GO:0001523 retinoid metabolic process 2/566 81/18722 0.707382187470146 0.795381379349876 LRP2/LRP1 2 GO:0021954 central nervous system neuron development 2/566 81/18722 0.707382187470146 0.795381379349876 HSP90AB1/NRP1 2 GO:0051149 positive regulation of muscle cell differentiation 2/566 81/18722 0.707382187470146 0.795381379349876 MORF4L2/ENG 2 GO:0060968 regulation of gene silencing 2/566 81/18722 0.707382187470146 0.795381379349876 NEAT1/EGFR 2 GO:0002714 positive regulation of B cell mediated immunity 1/566 40/18722 0.707482089448677 0.795381379349876 TFRC 1 GO:0002891 positive regulation of immunoglobulin mediated immune response 1/566 40/18722 0.707482089448677 0.795381379349876 TFRC 1 GO:0009069 serine family amino acid metabolic process 1/566 40/18722 0.707482089448677 0.795381379349876 GCSH 1 GO:0030866 cortical actin cytoskeleton organization 1/566 40/18722 0.707482089448677 0.795381379349876 CALR 1 GO:0031111 negative regulation of microtubule polymerization or depolymerization 1/566 40/18722 0.707482089448677 0.795381379349876 STMN1 1 GO:0032892 positive regulation of organic acid transport 1/566 40/18722 0.707482089448677 0.795381379349876 ITGB1 1 GO:0070266 necroptotic process 1/566 40/18722 0.707482089448677 0.795381379349876 YBX3 1 GO:0097352 autophagosome maturation 1/566 40/18722 0.707482089448677 0.795381379349876 CALM1 1 GO:0150077 regulation of neuroinflammatory response 1/566 40/18722 0.707482089448677 0.795381379349876 GRN 1 GO:1901223 negative regulation of NIK/NF-kappaB signaling 1/566 40/18722 0.707482089448677 0.795381379349876 TMSB4X 1 GO:0043244 regulation of protein-containing complex disassembly 3/566 121/18722 0.712704805926917 0.80084850984014 BNIP3/SCIN/IGF1R 3 GO:1904019 epithelial cell apoptotic process 3/566 121/18722 0.712704805926917 0.80084850984014 KRT8/KRT18/SERPINE1 3 GO:0007099 centriole replication 1/566 41/18722 0.716344370648337 0.803518553319828 NPM1 1 GO:0030488 tRNA methylation 1/566 41/18722 0.716344370648337 0.803518553319828 TRMT112 1 GO:0048286 lung alveolus development 1/566 41/18722 0.716344370648337 0.803518553319828 PTGES3 1 GO:0051693 actin filament capping 1/566 41/18722 0.716344370648337 0.803518553319828 SCIN 1 GO:0060612 adipose tissue development 1/566 41/18722 0.716344370648337 0.803518553319828 LRP5 1 GO:1903524 positive regulation of blood circulation 1/566 41/18722 0.716344370648337 0.803518553319828 ADRB1 1 GO:1905521 regulation of macrophage migration 1/566 41/18722 0.716344370648337 0.803518553319828 MIF 1 GO:0003231 cardiac ventricle development 3/566 123/18722 0.723050093278969 0.809893780617948 LRP2/ISL1/ENG 3 GO:0031570 DNA integrity checkpoint signaling 3/566 123/18722 0.723050093278969 0.809893780617948 RPL26/CDK1/TRIAP1 3 GO:0000266 mitochondrial fission 1/566 42/18722 0.724938615400387 0.809893780617948 BNIP3 1 GO:0007212 dopamine receptor signaling pathway 1/566 42/18722 0.724938615400387 0.809893780617948 GNAI3 1 GO:0010591 regulation of lamellipodium assembly 1/566 42/18722 0.724938615400387 0.809893780617948 ARPC2 1 GO:0014003 oligodendrocyte development 1/566 42/18722 0.724938615400387 0.809893780617948 GSTP1 1 GO:0021575 hindbrain morphogenesis 1/566 42/18722 0.724938615400387 0.809893780617948 SERPINE2 1 GO:0035019 somatic stem cell population maintenance 1/566 42/18722 0.724938615400387 0.809893780617948 LRP5 1 GO:0043507 positive regulation of JUN kinase activity 1/566 42/18722 0.724938615400387 0.809893780617948 RPS3 1 GO:0045292 mRNA cis splicing, via spliceosome 1/566 42/18722 0.724938615400387 0.809893780617948 RBM17 1 GO:0055090 acylglycerol homeostasis 1/566 42/18722 0.724938615400387 0.809893780617948 APOE 1 GO:0060999 positive regulation of dendritic spine development 1/566 42/18722 0.724938615400387 0.809893780617948 APOE 1 GO:0070328 triglyceride homeostasis 1/566 42/18722 0.724938615400387 0.809893780617948 APOE 1 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis 1/566 42/18722 0.724938615400387 0.809893780617948 PDCD10 1 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic 1/566 42/18722 0.724938615400387 0.809893780617948 EXOSC9 1 GO:1903432 regulation of TORC1 signaling 1/566 42/18722 0.724938615400387 0.809893780617948 PIH1D1 1 GO:1901617 organic hydroxy compound biosynthetic process 6/566 237/18722 0.72557430451706 0.810194484414735 APOE/PARK7/IMPA2/SLC27A2/ASAH1/P2RY6 6 GO:0021953 central nervous system neuron differentiation 4/566 162/18722 0.725749325710254 0.810194484414735 HSP90AB1/ISL1/B2M/NRP1 4 GO:0015844 monoamine transport 2/566 84/18722 0.726117698296224 0.810194484414735 SLC6A4/PARK7 2 GO:0045445 myoblast differentiation 2/566 84/18722 0.726117698296224 0.810194484414735 LGALS1/ISL1 2 GO:0061157 mRNA destabilization 2/566 84/18722 0.726117698296224 0.810194484414735 HNRNPD/EXOSC9 2 GO:0045216 cell-cell junction organization 5/566 200/18722 0.726680666117214 0.810619475207677 ACTG1/CDH1/SVEP1/GJA1/DSG2 5 GO:0007368 determination of left/right symmetry 3/566 124/18722 0.728112848748137 0.812013627912502 ENG/GALNT11/FOLR1 3 GO:0042509 regulation of tyrosine phosphorylation of STAT protein 2/566 85/18722 0.732133485368339 0.814300579709069 IL6ST/ISL1 2 GO:0007548 sex differentiation 7/566 276/18722 0.732757431955355 0.814300579709069 LRP2/HMGB2/YBX3/ADGRG1/CGA/EIF2S2/MEA1 7 GO:0001709 cell fate determination 1/566 43/18722 0.733272916454101 0.814300579709069 ISL1 1 GO:0010171 body morphogenesis 1/566 43/18722 0.733272916454101 0.814300579709069 DAG1 1 GO:0032365 intracellular lipid transport 1/566 43/18722 0.733272916454101 0.814300579709069 ABCA1 1 GO:0033173 calcineurin-NFAT signaling cascade 1/566 43/18722 0.733272916454101 0.814300579709069 ATP2B4 1 GO:0034142 toll-like receptor 4 signaling pathway 1/566 43/18722 0.733272916454101 0.814300579709069 HMGB1 1 GO:0034661 ncRNA catabolic process 1/566 43/18722 0.733272916454101 0.814300579709069 EXOSC9 1 GO:0042181 ketone biosynthetic process 1/566 43/18722 0.733272916454101 0.814300579709069 TPI1 1 GO:0045494 photoreceptor cell maintenance 1/566 43/18722 0.733272916454101 0.814300579709069 SLC2A1 1 GO:0045776 negative regulation of blood pressure 1/566 43/18722 0.733272916454101 0.814300579709069 ADRB1 1 GO:0060443 mammary gland morphogenesis 1/566 43/18722 0.733272916454101 0.814300579709069 LRP5 1 GO:0140353 lipid export from cell 1/566 43/18722 0.733272916454101 0.814300579709069 SPP1 1 GO:1901381 positive regulation of potassium ion transmembrane transport 1/566 43/18722 0.733272916454101 0.814300579709069 AKAP9 1 GO:1903793 positive regulation of anion transport 1/566 43/18722 0.733272916454101 0.814300579709069 ITGB1 1 GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation 1/566 43/18722 0.733272916454101 0.814300579709069 GSTP1 1 GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand 1/566 43/18722 0.733272916454101 0.814300579709069 PPP1CA 1 GO:0002700 regulation of production of molecular mediator of immune response 4/566 164/18722 0.734538940288564 0.815398936115341 CD74/HLA-A/B2M/TFRC 4 GO:0009913 epidermal cell differentiation 5/566 202/18722 0.734628286783161 0.815398936115341 ANXA1/KRT10/NME2/ASAH1/TXNIP 5 GO:0070085 glycosylation 6/566 240/18722 0.736554288123688 0.817332923909935 B4GALT1/GALNT11/MOGS/NANS/EDEM3/B3GNT3 6 GO:0031929 TOR signaling 3/566 126/18722 0.7380204229492 0.81836594101371 RPS6/PIH1D1/SMG1 3 GO:0032874 positive regulation of stress-activated MAPK cascade 3/566 126/18722 0.7380204229492 0.81836594101371 HMGB1/PDCD10/APP 3 GO:0006493 protein O-linked glycosylation 2/566 86/18722 0.738036669624898 0.81836594101371 GALNT11/B3GNT3 2 GO:0032869 cellular response to insulin stimulus 5/566 203/18722 0.738538623740267 0.818718613767845 PKM/GSTP1/IGF2/ATP2B1/IGF1R 5 GO:0002792 negative regulation of peptide secretion 1/566 44/18722 0.741355122636818 0.82020700943815 CD74 1 GO:0006378 mRNA polyadenylation 1/566 44/18722 0.741355122636818 0.82020700943815 APP 1 GO:0021517 ventral spinal cord development 1/566 44/18722 0.741355122636818 0.82020700943815 ISL1 1 GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT 1/566 44/18722 0.741355122636818 0.82020700943815 PRLR 1 GO:0048066 developmental pigmentation 1/566 44/18722 0.741355122636818 0.82020700943815 RAB38 1 GO:0048806 genitalia development 1/566 44/18722 0.741355122636818 0.82020700943815 LRP2 1 GO:0051150 regulation of smooth muscle cell differentiation 1/566 44/18722 0.741355122636818 0.82020700943815 ENG 1 GO:0060711 labyrinthine layer development 1/566 44/18722 0.741355122636818 0.82020700943815 SPINT1 1 GO:0060538 skeletal muscle organ development 4/566 166/18722 0.743115162307761 0.82194998822215 YBX3/GPX1/DAG1/IGF2 4 GO:0044070 regulation of anion transport 2/566 87/18722 0.743828547297506 0.822126289118296 ITGB1/SLC43A2 2 GO:0061014 positive regulation of mRNA catabolic process 2/566 87/18722 0.743828547297506 0.822126289118296 HNRNPD/EXOSC9 2 GO:1901606 alpha-amino acid catabolic process 2/566 87/18722 0.743828547297506 0.822126289118296 ATP2B4/GCSH 2 GO:0009101 glycoprotein biosynthetic process 8/566 317/18722 0.746153941751515 0.824109774153056 ITM2B/CHPF/B4GALT1/GALNT11/HS6ST2/MOGS/EDEM3/B3GNT3 8 GO:0009451 RNA modification 4/566 167/18722 0.747323668879353 0.824109774153056 SSB/TRMT112/NHP2/TPRKB 4 GO:0006639 acylglycerol metabolic process 3/566 128/18722 0.747640151200545 0.824109774153056 APOC1/APOE/GPX1 3 GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 3/566 128/18722 0.747640151200545 0.824109774153056 HMGB1/PDCD10/APP 3 GO:0002920 regulation of humoral immune response 1/566 45/18722 0.749192846193279 0.824109774153056 CD46 1 GO:0006110 regulation of glycolytic process 1/566 45/18722 0.749192846193279 0.824109774153056 APP 1 GO:0006903 vesicle targeting 1/566 45/18722 0.749192846193279 0.824109774153056 TFG 1 GO:0030835 negative regulation of actin filament depolymerization 1/566 45/18722 0.749192846193279 0.824109774153056 SCIN 1 GO:0032309 icosanoid secretion 1/566 45/18722 0.749192846193279 0.824109774153056 ANXA1 1 GO:0042551 neuron maturation 1/566 45/18722 0.749192846193279 0.824109774153056 APP 1 GO:0043631 RNA polyadenylation 1/566 45/18722 0.749192846193279 0.824109774153056 APP 1 GO:0044088 regulation of vacuole organization 1/566 45/18722 0.749192846193279 0.824109774153056 GRN 1 GO:0046189 phenol-containing compound biosynthetic process 1/566 45/18722 0.749192846193279 0.824109774153056 PARK7 1 GO:0048538 thymus development 1/566 45/18722 0.749192846193279 0.824109774153056 CCNB2 1 GO:0048599 oocyte development 1/566 45/18722 0.749192846193279 0.824109774153056 CCNB1 1 GO:0060119 inner ear receptor cell development 1/566 45/18722 0.749192846193279 0.824109774153056 NAGLU 1 GO:0071354 cellular response to interleukin-6 1/566 45/18722 0.749192846193279 0.824109774153056 IL6ST 1 GO:0098534 centriole assembly 1/566 45/18722 0.749192846193279 0.824109774153056 NPM1 1 GO:0007260 tyrosine phosphorylation of STAT protein 2/566 88/18722 0.749510439251061 0.824109774153056 IL6ST/ISL1 2 GO:0030101 natural killer cell activation 2/566 88/18722 0.749510439251061 0.824109774153056 TYROBP/PRDX1 2 GO:0050779 RNA destabilization 2/566 88/18722 0.749510439251061 0.824109774153056 HNRNPD/EXOSC9 2 GO:0006638 neutral lipid metabolic process 3/566 129/18722 0.752343183110891 0.827020210175232 APOC1/APOE/GPX1 3 GO:0046330 positive regulation of JNK cascade 2/566 89/18722 0.755083688316769 0.829450034857186 HMGB1/APP 2 GO:0051781 positive regulation of cell division 2/566 89/18722 0.755083688316769 0.829450034857186 YBX1/IGF2 2 GO:0007019 microtubule depolymerization 1/566 46/18722 0.756793469904507 0.829450034857186 STMN1 1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules 1/566 46/18722 0.756793469904507 0.829450034857186 TENM3 1 GO:0031018 endocrine pancreas development 1/566 46/18722 0.756793469904507 0.829450034857186 ANXA1 1 GO:0031057 negative regulation of histone modification 1/566 46/18722 0.756793469904507 0.829450034857186 PIH1D1 1 GO:0034198 cellular response to amino acid starvation 1/566 46/18722 0.756793469904507 0.829450034857186 SLC38A2 1 GO:0035094 response to nicotine 1/566 46/18722 0.756793469904507 0.829450034857186 B2M 1 GO:0044818 mitotic G2/M transition checkpoint 1/566 46/18722 0.756793469904507 0.829450034857186 CDK1 1 GO:0046839 phospholipid dephosphorylation 1/566 46/18722 0.756793469904507 0.829450034857186 PLPP3 1 GO:0048701 embryonic cranial skeleton morphogenesis 1/566 46/18722 0.756793469904507 0.829450034857186 EIF4A3 1 GO:0070828 heterochromatin organization 1/566 46/18722 0.756793469904507 0.829450034857186 POLE3 1 GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 3/566 130/18722 0.756975627049584 0.829450034857186 TFG/LMAN1/NRBP1 3 GO:0006836 neurotransmitter transport 5/566 208/18722 0.757458362452167 0.829691731960014 CALM1/SLC6A4/PARK7/SLC38A2/ITGB1 5 GO:0003007 heart morphogenesis 6/566 246/18722 0.75756893315756 0.829691731960014 LRP2/ISL1/NRP1/ENG/GAA/FOLR1 6 GO:0006520 cellular amino acid metabolic process 7/566 284/18722 0.759021365697331 0.830873646443205 ATP2B4/SMS/PARK7/GCSH/MTHFS/ECHS1/GMPS 7 GO:0015850 organic hydroxy compound transport 7/566 284/18722 0.759021365697331 0.830873646443205 APOC1/APOE/SPP1/LRP1/SLC6A4/PARK7/ABCA1 7 GO:0018022 peptidyl-lysine methylation 3/566 131/18722 0.761537982132663 0.833423573366425 TRMT112/DPY30/PIH1D1 3 GO:0051048 negative regulation of secretion 4/566 171/18722 0.763631701851253 0.833429400680109 CD74/APOE/ANXA1/GJA1 4 GO:0006998 nuclear envelope organization 1/566 47/18722 0.764164153992858 0.833429400680109 VRK1 1 GO:0010761 fibroblast migration 1/566 47/18722 0.764164153992858 0.833429400680109 ITGB1 1 GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 1/566 47/18722 0.764164153992858 0.833429400680109 GSTP1 1 GO:0031641 regulation of myelination 1/566 47/18722 0.764164153992858 0.833429400680109 DAG1 1 GO:0032008 positive regulation of TOR signaling 1/566 47/18722 0.764164153992858 0.833429400680109 PIH1D1 1 GO:0035850 epithelial cell differentiation involved in kidney development 1/566 47/18722 0.764164153992858 0.833429400680109 IQGAP1 1 GO:0043114 regulation of vascular permeability 1/566 47/18722 0.764164153992858 0.833429400680109 APOE 1 GO:0045911 positive regulation of DNA recombination 1/566 47/18722 0.764164153992858 0.833429400680109 TFRC 1 GO:0051489 regulation of filopodium assembly 1/566 47/18722 0.764164153992858 0.833429400680109 NRP1 1 GO:0061001 regulation of dendritic spine morphogenesis 1/566 47/18722 0.764164153992858 0.833429400680109 CFL1 1 GO:0072583 clathrin-dependent endocytosis 1/566 47/18722 0.764164153992858 0.833429400680109 CANX 1 GO:0090279 regulation of calcium ion import 1/566 47/18722 0.764164153992858 0.833429400680109 VDAC1 1 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis 1/566 47/18722 0.764164153992858 0.833429400680109 PDCD10 1 GO:0042147 retrograde transport, endosome to Golgi 2/566 91/18722 0.765909723900741 0.834924116260063 SNX2/VPS29 2 GO:0051952 regulation of amine transport 2/566 91/18722 0.765909723900741 0.834924116260063 ITGB1/SLC43A2 2 GO:0002221 pattern recognition receptor signaling pathway 4/566 172/18722 0.767578361362251 0.836538277793082 HMGB1/CYBA/HSPD1/COLEC12 4 GO:0009855 determination of bilateral symmetry 3/566 133/18722 0.770454510685266 0.83896416423968 ENG/GALNT11/FOLR1 3 GO:0035249 synaptic transmission, glutamatergic 2/566 92/18722 0.771165283810054 0.83896416423968 SERPINE2/EGFR 2 GO:0070509 calcium ion import 2/566 92/18722 0.771165283810054 0.83896416423968 VDAC1/ATP2B4 2 GO:0032527 protein exit from endoplasmic reticulum 1/566 48/18722 0.771311842819634 0.83896416423968 HSP90B1 1 GO:0061647 histone H3-K9 modification 1/566 48/18722 0.771311842819634 0.83896416423968 PIH1D1 1 GO:0090311 regulation of protein deacetylation 1/566 48/18722 0.771311842819634 0.83896416423968 BEX4 1 GO:0097720 calcineurin-mediated signaling 1/566 48/18722 0.771311842819634 0.83896416423968 ATP2B4 1 GO:1902003 regulation of amyloid-beta formation 1/566 48/18722 0.771311842819634 0.83896416423968 APOE 1 GO:0008277 regulation of G protein-coupled receptor signaling pathway 3/566 134/18722 0.774809767804016 0.842151632388545 ATP2B4/STMN1/MET 3 GO:0009799 specification of symmetry 3/566 134/18722 0.774809767804016 0.842151632388545 ENG/GALNT11/FOLR1 3 GO:0042552 myelination 3/566 134/18722 0.774809767804016 0.842151632388545 DAG1/ITGB4/HEXB 3 GO:0060349 bone morphogenesis 2/566 93/18722 0.776317743195302 0.842592180007391 LRP5/GLG1 2 GO:0061448 connective tissue development 6/566 252/18722 0.777331393336222 0.842592180007391 TYMS/ITGB8/EFEMP1/LRP5/SCIN/GLG1 6 GO:0006376 mRNA splice site selection 1/566 49/18722 0.778243271381489 0.842592180007391 SRSF9 1 GO:0006953 acute-phase response 1/566 49/18722 0.778243271381489 0.842592180007391 FN1 1 GO:0008206 bile acid metabolic process 1/566 49/18722 0.778243271381489 0.842592180007391 SLC27A2 1 GO:0009066 aspartate family amino acid metabolic process 1/566 49/18722 0.778243271381489 0.842592180007391 SMS 1 GO:0009395 phospholipid catabolic process 1/566 49/18722 0.778243271381489 0.842592180007391 APOC1 1 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation 1/566 49/18722 0.778243271381489 0.842592180007391 ENG 1 GO:0021515 cell differentiation in spinal cord 1/566 49/18722 0.778243271381489 0.842592180007391 ISL1 1 GO:0034332 adherens junction organization 1/566 49/18722 0.778243271381489 0.842592180007391 CDH1 1 GO:0043330 response to exogenous dsRNA 1/566 49/18722 0.778243271381489 0.842592180007391 COLEC12 1 GO:0050832 defense response to fungus 1/566 49/18722 0.778243271381489 0.842592180007391 GAPDH 1 GO:0070741 response to interleukin-6 1/566 49/18722 0.778243271381489 0.842592180007391 IL6ST 1 GO:0072666 establishment of protein localization to vacuole 1/566 49/18722 0.778243271381489 0.842592180007391 VPS13C 1 GO:0086009 membrane repolarization 1/566 49/18722 0.778243271381489 0.842592180007391 AKAP9 1 GO:1904894 positive regulation of receptor signaling pathway via STAT 1/566 49/18722 0.778243271381489 0.842592180007391 PRLR 1 GO:0007272 ensheathment of neurons 3/566 136/18722 0.783317090043437 0.846165630415287 DAG1/ITGB4/HEXB 3 GO:0008366 axon ensheathment 3/566 136/18722 0.783317090043437 0.846165630415287 DAG1/ITGB4/HEXB 3 GO:0043624 cellular protein complex disassembly 3/566 136/18722 0.783317090043437 0.846165630415287 STMN1/CFL1/SCIN 3 GO:0001961 positive regulation of cytokine-mediated signaling pathway 1/566 50/18722 0.784964971611665 0.846165630415287 CD74 1 GO:0002639 positive regulation of immunoglobulin production 1/566 50/18722 0.784964971611665 0.846165630415287 TFRC 1 GO:0010665 regulation of cardiac muscle cell apoptotic process 1/566 50/18722 0.784964971611665 0.846165630415287 BNIP3 1 GO:0015872 dopamine transport 1/566 50/18722 0.784964971611665 0.846165630415287 PARK7 1 GO:0018023 peptidyl-lysine trimethylation 1/566 50/18722 0.784964971611665 0.846165630415287 PIH1D1 1 GO:0038093 Fc receptor signaling pathway 1/566 50/18722 0.784964971611665 0.846165630415287 FCER1G 1 GO:0043268 positive regulation of potassium ion transport 1/566 50/18722 0.784964971611665 0.846165630415287 AKAP9 1 GO:0045058 T cell selection 1/566 50/18722 0.784964971611665 0.846165630415287 CD74 1 GO:0045814 negative regulation of gene expression, epigenetic 1/566 50/18722 0.784964971611665 0.846165630415287 POLE3 1 GO:0060425 lung morphogenesis 1/566 50/18722 0.784964971611665 0.846165630415287 DAG1 1 GO:0070231 T cell apoptotic process 1/566 50/18722 0.784964971611665 0.846165630415287 RPS6 1 GO:0071709 membrane assembly 1/566 50/18722 0.784964971611665 0.846165630415287 S100A10 1 GO:0090102 cochlea development 1/566 50/18722 0.784964971611665 0.846165630415287 CCNA2 1 GO:0099054 presynapse assembly 1/566 50/18722 0.784964971611665 0.846165630415287 APP 1 GO:1904036 negative regulation of epithelial cell apoptotic process 1/566 50/18722 0.784964971611665 0.846165630415287 SERPINE1 1 GO:0042982 amyloid precursor protein metabolic process 2/566 95/18722 0.786319038239055 0.847214994733851 APOE/ITM2B 2 GO:1901379 regulation of potassium ion transmembrane transport 2/566 95/18722 0.786319038239055 0.847214994733851 ITGB1/AKAP9 2 GO:0043547 positive regulation of GTPase activity 6/566 255/18722 0.786748481299817 0.84747259587389 ZC3H15/ITGA6/S100A10/PLXNB1/ITGB1/ADRB1 6 GO:0060078 regulation of postsynaptic membrane potential 3/566 137/18722 0.78747032540686 0.848044965822773 EIF4A3/APP/ADRB1 3 GO:0035282 segmentation 2/566 96/18722 0.791170732676348 0.851336930622361 SEMA3F/NRP1 2 GO:0042158 lipoprotein biosynthetic process 2/566 96/18722 0.791170732676348 0.851336930622361 APOE/ABCA1 2 GO:0014009 glial cell proliferation 1/566 51/18722 0.791483278491903 0.851336930622361 EGFR 1 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling 1/566 51/18722 0.791483278491903 0.851336930622361 GSTP1 1 GO:0050982 detection of mechanical stimulus 1/566 51/18722 0.791483278491903 0.851336930622361 SERPINE2 1 GO:0007163 establishment or maintenance of cell polarity 5/566 218/18722 0.792185042352079 0.851885944094554 HSP90AB1/MAD2L1/ARPC5/ITGB1/GJA1 5 GO:1901216 positive regulation of neuron death 2/566 97/18722 0.795925040617672 0.855701106213445 TYROBP/GRN 2 GO:0010662 regulation of striated muscle cell apoptotic process 1/566 52/18722 0.797804335980714 0.857100604195496 BNIP3 1 GO:0035176 social behavior 1/566 52/18722 0.797804335980714 0.857100604195496 SLC6A4 1 GO:0060071 Wnt signaling pathway, planar cell polarity pathway 1/566 52/18722 0.797804335980714 0.857100604195496 ZNRF3 1 GO:0016571 histone methylation 3/566 141/18722 0.803427974292818 0.862437259157391 TRMT112/DPY30/PIH1D1 3 GO:0030183 B cell differentiation 3/566 141/18722 0.803427974292818 0.862437259157391 LGALS1/SLC25A5/ITGB1 3 GO:0033059 cellular pigmentation 1/566 53/18722 0.803934102763516 0.862437259157391 RAB38 1 GO:0043113 receptor clustering 1/566 53/18722 0.803934102763516 0.862437259157391 APOE 1 GO:0071715 icosanoid transport 1/566 53/18722 0.803934102763516 0.862437259157391 ANXA1 1 GO:0099172 presynapse organization 1/566 53/18722 0.803934102763516 0.862437259157391 APP 1 GO:0000045 autophagosome assembly 2/566 99/18722 0.805147264919399 0.862699307682591 GABARAP/TMEM41B 2 GO:0002444 myeloid leukocyte mediated immunity 2/566 99/18722 0.805147264919399 0.862699307682591 TYROBP/ANXA3 2 GO:0015837 amine transport 2/566 99/18722 0.805147264919399 0.862699307682591 ITGB1/SLC43A2 2 GO:0051153 regulation of striated muscle cell differentiation 2/566 99/18722 0.805147264919399 0.862699307682591 YBX1/MORF4L2 2 GO:0060996 dendritic spine development 2/566 99/18722 0.805147264919399 0.862699307682591 APOE/CFL1 2 GO:0072006 nephron development 3/566 142/18722 0.807256713742041 0.864439810371393 LAMA5/IQGAP1/SEC61A1 3 GO:0051588 regulation of neurotransmitter transport 2/566 100/18722 0.809618068792539 0.864439810371393 CALM1/ITGB1 2 GO:0060079 excitatory postsynaptic potential 2/566 100/18722 0.809618068792539 0.864439810371393 EIF4A3/APP 2 GO:0061640 cytoskeleton-dependent cytokinesis 2/566 100/18722 0.809618068792539 0.864439810371393 STMN1/CHMP5 2 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis 1/566 54/18722 0.809878357829982 0.864439810371393 PDCD10 1 GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1/566 54/18722 0.809878357829982 0.864439810371393 CD46 1 GO:0006584 catecholamine metabolic process 1/566 54/18722 0.809878357829982 0.864439810371393 PARK7 1 GO:0007215 glutamate receptor signaling pathway 1/566 54/18722 0.809878357829982 0.864439810371393 APP 1 GO:0009712 catechol-containing compound metabolic process 1/566 54/18722 0.809878357829982 0.864439810371393 PARK7 1 GO:0010659 cardiac muscle cell apoptotic process 1/566 54/18722 0.809878357829982 0.864439810371393 BNIP3 1 GO:0014888 striated muscle adaptation 1/566 54/18722 0.809878357829982 0.864439810371393 ATP2B4 1 GO:0030520 intracellular estrogen receptor signaling pathway 1/566 54/18722 0.809878357829982 0.864439810371393 ISL1 1 GO:0030834 regulation of actin filament depolymerization 1/566 54/18722 0.809878357829982 0.864439810371393 SCIN 1 GO:0051703 biological process involved in intraspecies interaction between organisms 1/566 54/18722 0.809878357829982 0.864439810371393 SLC6A4 1 GO:1902743 regulation of lamellipodium organization 1/566 54/18722 0.809878357829982 0.864439810371393 ARPC2 1 GO:2000300 regulation of synaptic vesicle exocytosis 1/566 54/18722 0.809878357829982 0.864439810371393 CALM1 1 GO:0070555 response to interleukin-1 3/566 143/18722 0.811022475932278 0.865453514585451 ANXA1/CYBA/APP 3 GO:0006476 protein deacetylation 2/566 101/18722 0.813997258408665 0.868419792579769 MORF4L2/BEX4 2 GO:0000768 syncytium formation by plasma membrane fusion 1/566 55/18722 0.815642705883776 0.868510243146274 TYROBP 1 GO:0008333 endosome to lysosome transport 1/566 55/18722 0.815642705883776 0.868510243146274 CHMP5 1 GO:0044091 membrane biogenesis 1/566 55/18722 0.815642705883776 0.868510243146274 S100A10 1 GO:0048016 inositol phosphate-mediated signaling 1/566 55/18722 0.815642705883776 0.868510243146274 ATP2B4 1 GO:0051898 negative regulation of protein kinase B signaling 1/566 55/18722 0.815642705883776 0.868510243146274 DAG1 1 GO:0140253 cell-cell fusion 1/566 55/18722 0.815642705883776 0.868510243146274 TYROBP 1 GO:1902991 regulation of amyloid precursor protein catabolic process 1/566 55/18722 0.815642705883776 0.868510243146274 APOE 1 GO:1905517 macrophage migration 1/566 55/18722 0.815642705883776 0.868510243146274 MIF 1 GO:0006486 protein glycosylation 5/566 226/18722 0.817072658617963 0.869616896047614 B4GALT1/GALNT11/MOGS/EDEM3/B3GNT3 5 GO:0043413 macromolecule glycosylation 5/566 226/18722 0.817072658617963 0.869616896047614 B4GALT1/GALNT11/MOGS/EDEM3/B3GNT3 5 GO:0045833 negative regulation of lipid metabolic process 2/566 102/18722 0.818286274958117 0.870700405380865 APOC1/APOE 2 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 1/566 56/18722 0.821232582589716 0.87258411878029 EXOSC9 1 GO:0001658 branching involved in ureteric bud morphogenesis 1/566 56/18722 0.821232582589716 0.87258411878029 LAMA5 1 GO:0002886 regulation of myeloid leukocyte mediated immunity 1/566 56/18722 0.821232582589716 0.87258411878029 TYROBP 1 GO:0010658 striated muscle cell apoptotic process 1/566 56/18722 0.821232582589716 0.87258411878029 BNIP3 1 GO:0042733 embryonic digit morphogenesis 1/566 56/18722 0.821232582589716 0.87258411878029 LRP5 1 GO:0090175 regulation of establishment of planar polarity 1/566 56/18722 0.821232582589716 0.87258411878029 ZNRF3 1 GO:0048813 dendrite morphogenesis 3/566 146/18722 0.821948528718804 0.873083011207215 CFL1/NRP1/ITGB1 3 GO:0030148 sphingolipid biosynthetic process 2/566 103/18722 0.822486556379842 0.873083011207215 PLPP3/ASAH1 2 GO:0050773 regulation of dendrite development 2/566 103/18722 0.822486556379842 0.873083011207215 CDC20/IQGAP1 2 GO:1905037 autophagosome organization 2/566 103/18722 0.822486556379842 0.873083011207215 GABARAP/TMEM41B 2 GO:1903531 negative regulation of secretion by cell 3/566 147/18722 0.825469042606881 0.875418723125761 APOE/ANXA1/GJA1 3 GO:0071695 anatomical structure maturation 5/566 229/18722 0.825767742036149 0.875418723125761 TYMS/CCNB1/PLXNB1/DAG1/APP 5 GO:0006695 cholesterol biosynthetic process 1/566 57/18722 0.82665325966323 0.875418723125761 APOE 1 GO:0006949 syncytium formation 1/566 57/18722 0.82665325966323 0.875418723125761 TYROBP 1 GO:0034205 amyloid-beta formation 1/566 57/18722 0.82665325966323 0.875418723125761 APOE 1 GO:0051155 positive regulation of striated muscle cell differentiation 1/566 57/18722 0.82665325966323 0.875418723125761 MORF4L2 1 GO:0060760 positive regulation of response to cytokine stimulus 1/566 57/18722 0.82665325966323 0.875418723125761 CD74 1 GO:0061005 cell differentiation involved in kidney development 1/566 57/18722 0.82665325966323 0.875418723125761 IQGAP1 1 GO:0061756 leukocyte adhesion to vascular endothelial cell 1/566 57/18722 0.82665325966323 0.875418723125761 ITGB1 1 GO:1902653 secondary alcohol biosynthetic process 1/566 57/18722 0.82665325966323 0.875418723125761 APOE 1 GO:0016197 endosomal transport 5/566 230/18722 0.828590818712224 0.877261908420171 SNX2/VPS29/CHMP5/ABCA1/DPY30 5 GO:0062207 regulation of pattern recognition receptor signaling pathway 2/566 105/18722 0.8306266426951 0.879208229500377 HMGB1/CYBA 2 GO:0007405 neuroblast proliferation 1/566 58/18722 0.831909849806847 0.879312120451112 PLXNB2 1 GO:0010043 response to zinc ion 1/566 58/18722 0.831909849806847 0.879312120451112 MT2A 1 GO:0010559 regulation of glycoprotein biosynthetic process 1/566 58/18722 0.831909849806847 0.879312120451112 ITM2B 1 GO:0045604 regulation of epidermal cell differentiation 1/566 58/18722 0.831909849806847 0.879312120451112 NME2 1 GO:2000649 regulation of sodium ion transmembrane transporter activity 1/566 58/18722 0.831909849806847 0.879312120451112 GLRX 1 GO:2000736 regulation of stem cell differentiation 1/566 58/18722 0.831909849806847 0.879312120451112 HSPA9 1 GO:0006906 vesicle fusion 2/566 106/18722 0.834569297486987 0.881704440534425 ANXA1/GNAI3 2 GO:0099565 chemical synaptic transmission, postsynaptic 2/566 106/18722 0.834569297486987 0.881704440534425 EIF4A3/APP 2 GO:0001959 regulation of cytokine-mediated signaling pathway 3/566 150/18722 0.83567562600875 0.882663792880416 CD74/HSP90AB1/GSTP1 3 GO:0002820 negative regulation of adaptive immune response 1/566 59/18722 0.837007311498303 0.883441572022391 CD46 1 GO:0043551 regulation of phosphatidylinositol 3-kinase activity 1/566 59/18722 0.837007311498303 0.883441572022391 FLT1 1 GO:2000351 regulation of endothelial cell apoptotic process 1/566 59/18722 0.837007311498303 0.883441572022391 SERPINE1 1 GO:0055067 monovalent inorganic cation homeostasis 3/566 151/18722 0.83896180193204 0.885294605878511 GRN/ATP6AP1/RAB38 3 GO:0009620 response to fungus 1/566 60/18722 0.84195045363472 0.886827134837342 GAPDH 1 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 1/566 60/18722 0.84195045363472 0.886827134837342 CDK1 1 GO:0019731 antibacterial humoral response 1/566 60/18722 0.84195045363472 0.886827134837342 HLA-A 1 GO:0033866 nucleoside bisphosphate biosynthetic process 1/566 60/18722 0.84195045363472 0.886827134837342 SLC26A2 1 GO:0034030 ribonucleoside bisphosphate biosynthetic process 1/566 60/18722 0.84195045363472 0.886827134837342 SLC26A2 1 GO:0034033 purine nucleoside bisphosphate biosynthetic process 1/566 60/18722 0.84195045363472 0.886827134837342 SLC26A2 1 GO:0090501 RNA phosphodiester bond hydrolysis 3/566 152/18722 0.842191126378511 0.886827134837342 NHP2/RNASEH2A/EXOSC9 3 GO:0098659 inorganic cation import across plasma membrane 2/566 108/18722 0.842206901637978 0.886827134837342 ATP2B4/SLC39A10 2 GO:0099587 inorganic ion import across plasma membrane 2/566 108/18722 0.842206901637978 0.886827134837342 ATP2B4/SLC39A10 2 GO:0120254 olefinic compound metabolic process 3/566 153/18722 0.845364297330496 0.889920684854942 GSTP1/PTGES3/GPX1 3 GO:0043266 regulation of potassium ion transport 2/566 109/18722 0.845904654538538 0.889920684854942 ITGB1/AKAP9 2 GO:0072009 nephron epithelium development 2/566 109/18722 0.845904654538538 0.889920684854942 LAMA5/IQGAP1 2 GO:0030199 collagen fibril organization 1/566 61/18722 0.846743940037182 0.889920684854942 COL14A1 1 GO:0030865 cortical cytoskeleton organization 1/566 61/18722 0.846743940037182 0.889920684854942 CALR 1 GO:0050994 regulation of lipid catabolic process 1/566 61/18722 0.846743940037182 0.889920684854942 APOC1 1 GO:0060997 dendritic spine morphogenesis 1/566 61/18722 0.846743940037182 0.889920684854942 CFL1 1 GO:0060998 regulation of dendritic spine development 1/566 61/18722 0.846743940037182 0.889920684854942 APOE 1 GO:0006959 humoral immune response 7/566 317/18722 0.84763265532989 0.890644461064119 GAPDH/LYZ/HLA-DRB1/HLA-A/HMGN2/RPS19/CD46 7 GO:0006939 smooth muscle contraction 2/566 110/18722 0.849523561320705 0.891789411695302 ATP2B4/ATP2B1 2 GO:0030317 flagellated sperm motility 2/566 110/18722 0.849523561320705 0.891789411695302 ATP2B4/DNAJA1 2 GO:0090174 organelle membrane fusion 2/566 110/18722 0.849523561320705 0.891789411695302 ANXA1/GNAI3 2 GO:0097722 sperm motility 2/566 110/18722 0.849523561320705 0.891789411695302 ATP2B4/DNAJA1 2 GO:0007062 sister chromatid cohesion 1/566 62/18722 0.851392293819882 0.892228345685599 CDC20 1 GO:0032835 glomerulus development 1/566 62/18722 0.851392293819882 0.892228345685599 IQGAP1 1 GO:0046148 pigment biosynthetic process 1/566 62/18722 0.851392293819882 0.892228345685599 GMPS 1 GO:0048663 neuron fate commitment 1/566 62/18722 0.851392293819882 0.892228345685599 ISL1 1 GO:0060113 inner ear receptor cell differentiation 1/566 62/18722 0.851392293819882 0.892228345685599 NAGLU 1 GO:0060675 ureteric bud morphogenesis 1/566 62/18722 0.851392293819882 0.892228345685599 LAMA5 1 GO:1902750 negative regulation of cell cycle G2/M phase transition 1/566 62/18722 0.851392293819882 0.892228345685599 CDK1 1 GO:0007519 skeletal muscle tissue development 3/566 155/18722 0.851544977721948 0.892228345685599 YBX3/GPX1/IGF2 3 GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 1/566 63/18722 0.855899901627918 0.896369410032343 PARK7 1 GO:0072171 mesonephric tubule morphogenesis 1/566 63/18722 0.855899901627918 0.896369410032343 LAMA5 1 GO:0035601 protein deacylation 2/566 112/18722 0.856530334150072 0.896818684768608 MORF4L2/BEX4 2 GO:0099003 vesicle-mediated transport in synapse 4/566 200/18722 0.858344551736209 0.898506923190596 CALM1/ACTG1/CLSTN1/CANX 4 GO:0006940 regulation of smooth muscle contraction 1/566 64/18722 0.860271017747677 0.899254888709242 ATP2B1 1 GO:0016126 sterol biosynthetic process 1/566 64/18722 0.860271017747677 0.899254888709242 APOE 1 GO:0017156 calcium-ion regulated exocytosis 1/566 64/18722 0.860271017747677 0.899254888709242 SCIN 1 GO:0046579 positive regulation of Ras protein signal transduction 1/566 64/18722 0.860271017747677 0.899254888709242 ADGRG1 1 GO:0046888 negative regulation of hormone secretion 1/566 64/18722 0.860271017747677 0.899254888709242 GJA1 1 GO:1903018 regulation of glycoprotein metabolic process 1/566 64/18722 0.860271017747677 0.899254888709242 ITM2B 1 GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 2/566 114/18722 0.863238101432874 0.902144607412947 HSP90AB1/ENG 2 GO:0019722 calcium-mediated signaling 4/566 202/18722 0.863488501099175 0.902194509949197 CALM1/ATP2B4/EGFR/GSTO1 4 GO:0046503 glycerolipid catabolic process 1/566 65/18722 0.864509768093632 0.902414416776752 APOC1 1 GO:0046513 ceramide biosynthetic process 1/566 65/18722 0.864509768093632 0.902414416776752 ASAH1 1 GO:0072577 endothelial cell apoptotic process 1/566 65/18722 0.864509768093632 0.902414416776752 SERPINE1 1 GO:1905330 regulation of morphogenesis of an epithelium 1/566 65/18722 0.864509768093632 0.902414416776752 GJA1 1 GO:0042471 ear morphogenesis 2/566 115/18722 0.866483205651082 0.90426236089044 RPL38/NAGLU 2 GO:0045600 positive regulation of fat cell differentiation 1/566 66/18722 0.868620154075247 0.906067695862934 LRP5 1 GO:0046626 regulation of insulin receptor signaling pathway 1/566 66/18722 0.868620154075247 0.906067695862934 IGF2 1 GO:0008286 insulin receptor signaling pathway 2/566 116/18722 0.869657549947112 0.906300424242636 IGF2/IGF1R 2 GO:0030326 embryonic limb morphogenesis 2/566 116/18722 0.869657549947112 0.906300424242636 FBN2/LRP5 2 GO:0035113 embryonic appendage morphogenesis 2/566 116/18722 0.869657549947112 0.906300424242636 FBN2/LRP5 2 GO:0098732 macromolecule deacylation 2/566 116/18722 0.869657549947112 0.906300424242636 MORF4L2/BEX4 2 GO:0060759 regulation of response to cytokine stimulus 3/566 162/18722 0.8715114822696 0.908019920211622 CD74/HSP90AB1/GSTP1 3 GO:0006513 protein monoubiquitination 1/566 67/18722 0.872606056347621 0.908048228698385 UBE2T 1 GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger 1/566 67/18722 0.872606056347621 0.908048228698385 ANXA1 1 GO:0042490 mechanoreceptor differentiation 1/566 67/18722 0.872606056347621 0.908048228698385 NAGLU 1 GO:0072665 protein localization to vacuole 1/566 67/18722 0.872606056347621 0.908048228698385 VPS13C 1 GO:0014902 myotube differentiation 2/566 117/18722 0.872762437241777 0.908048228698385 GPX1/PLD3 2 GO:0072676 lymphocyte migration 2/566 117/18722 0.872762437241777 0.908048228698385 APP/AIF1 2 GO:0061025 membrane fusion 3/566 163/18722 0.874161618515154 0.90929147795081 ANXA1/GNAI3/FOLR1 3 GO:0007585 respiratory gaseous exchange by respiratory system 1/566 68/18722 0.876471238449323 0.911055324206488 GAA 1 GO:0042987 amyloid precursor protein catabolic process 1/566 68/18722 0.876471238449323 0.911055324206488 APOE 1 GO:1904888 cranial skeletal system development 1/566 68/18722 0.876471238449323 0.911055324206488 EIF4A3 1 GO:0007286 spermatid development 3/566 165/18722 0.879317165503004 0.913800191601161 DYNLL1/HMGB2/CCNB1IP1 3 GO:0031060 regulation of histone methylation 1/566 69/18722 0.880219350330833 0.914310907063198 PIH1D1 1 GO:0050688 regulation of defense response to virus 1/566 69/18722 0.880219350330833 0.914310907063198 HTRA1 1 GO:0045123 cellular extravasation 1/566 70/18722 0.88385393177686 0.917658046704893 ITGB1 1 GO:0070830 bicellular tight junction assembly 1/566 70/18722 0.88385393177686 0.917658046704893 GJA1 1 GO:0055088 lipid homeostasis 3/566 167/18722 0.884284321849322 0.917890837228534 APOE/ABCA1/LRP5 3 GO:0048706 embryonic skeletal system development 2/566 121/18722 0.884512979580558 0.917914169019264 EIF4A3/KIAA1217 2 GO:0016482 cytosolic transport 3/566 168/18722 0.886698957520409 0.919968249564404 SNX2/VPS29/VPS13C 3 GO:0003281 ventricular septum development 1/566 71/18722 0.887378415725729 0.920029973640183 LRP2 1 GO:0043550 regulation of lipid kinase activity 1/566 71/18722 0.887378415725729 0.920029973640183 FLT1 1 GO:0072078 nephron tubule morphogenesis 1/566 71/18722 0.887378415725729 0.920029973640183 LAMA5 1 GO:0001505 regulation of neurotransmitter levels 4/566 213/18722 0.889006105954865 0.921502953134123 CALM1/SLC6A4/PARK7/ITGB1 4 GO:0001736 establishment of planar polarity 1/566 72/18722 0.890796131488918 0.922070303973183 ZNRF3 1 GO:0002534 cytokine production involved in inflammatory response 1/566 72/18722 0.890796131488918 0.922070303973183 PLD3 1 GO:0007164 establishment of tissue polarity 1/566 72/18722 0.890796131488918 0.922070303973183 ZNRF3 1 GO:0035567 non-canonical Wnt signaling pathway 1/566 72/18722 0.890796131488918 0.922070303973183 ZNRF3 1 GO:1900015 regulation of cytokine production involved in inflammatory response 1/566 72/18722 0.890796131488918 0.922070303973183 PLD3 1 GO:1901880 negative regulation of protein depolymerization 1/566 72/18722 0.890796131488918 0.922070303973183 SCIN 1 GO:0007259 receptor signaling pathway via JAK-STAT 3/566 170/18722 0.891393719643092 0.922474393270815 IL6ST/ISL1/PRLR 3 GO:0048469 cell maturation 3/566 171/18722 0.893675184246518 0.923568234490481 TYMS/CCNB1/APP 3 GO:0002637 regulation of immunoglobulin production 1/566 73/18722 0.894110307873758 0.923568234490481 TFRC 1 GO:0032456 endocytic recycling 1/566 73/18722 0.894110307873758 0.923568234490481 VPS29 1 GO:0042058 regulation of epidermal growth factor receptor signaling pathway 1/566 73/18722 0.894110307873758 0.923568234490481 EGFR 1 GO:0043299 leukocyte degranulation 1/566 73/18722 0.894110307873758 0.923568234490481 ANXA3 1 GO:0051145 smooth muscle cell differentiation 1/566 73/18722 0.894110307873758 0.923568234490481 ENG 1 GO:0051937 catecholamine transport 1/566 73/18722 0.894110307873758 0.923568234490481 PARK7 1 GO:0072088 nephron epithelium morphogenesis 1/566 73/18722 0.894110307873758 0.923568234490481 LAMA5 1 GO:0060294 cilium movement involved in cell motility 2/566 125/18722 0.895252685461605 0.924533740588046 ATP2B4/DNAJA1 2 GO:0048515 spermatid differentiation 3/566 172/18722 0.895913589386475 0.925001692937984 DYNLL1/HMGB2/CCNB1IP1 3 GO:0046323 glucose import 1/566 74/18722 0.897324076212192 0.926028462516616 SLC2A1 1 GO:1901568 fatty acid derivative metabolic process 1/566 74/18722 0.897324076212192 0.926028462516616 HPGD 1 GO:0000910 cytokinesis 3/566 173/18722 0.898109592950584 0.926624312355967 CALM1/STMN1/CHMP5 3 GO:0042445 hormone metabolic process 4/566 218/18722 0.899159583443956 0.927492693580281 SPP1/CGA/MME/CTSB 4 GO:0006911 phagocytosis, engulfment 2/566 127/18722 0.900267451912043 0.928168786090425 ABCA1/AIF1 2 GO:0006094 gluconeogenesis 1/566 75/18722 0.900440473298416 0.928168786090425 TPI1 1 GO:0008088 axo-dendritic transport 1/566 75/18722 0.900440473298416 0.928168786090425 APP 1 GO:0048705 skeletal system morphogenesis 4/566 220/18722 0.902986512445946 0.930577766992906 FBN2/EIF4A3/LRP5/GLG1 4 GO:0072028 nephron morphogenesis 1/566 76/18722 0.903462444238143 0.930852765968112 LAMA5 1 GO:0030522 intracellular receptor signaling pathway 5/566 265/18722 0.90608624811489 0.933340114902242 DNAJA1/PTGES3/ISL1/PARK7/CALR 5 GO:0140056 organelle localization by membrane tethering 1/566 77/18722 0.906392845212144 0.933439959954768 CALM1 1 GO:0030534 adult behavior 2/566 130/18722 0.90737155914995 0.934231771816739 PARK7/APP 2 GO:0035725 sodium ion transmembrane transport 3/566 178/18722 0.90847626652524 0.935152910652109 ATP2B4/SLC6A4/GLRX 3 GO:0019319 hexose biosynthetic process 1/566 78/18722 0.909234446156629 0.935261914463812 TPI1 1 GO:0043297 apical junction assembly 1/566 78/18722 0.909234446156629 0.935261914463812 GJA1 1 GO:0006661 phosphatidylinositol biosynthetic process 2/566 131/18722 0.909632544840141 0.935261914463812 IMPA2/SMG1 2 GO:0019827 stem cell population maintenance 2/566 131/18722 0.909632544840141 0.935261914463812 TPT1/LRP5 2 GO:0050853 B cell receptor signaling pathway 2/566 131/18722 0.909632544840141 0.935261914463812 SLC39A10/MNDA 2 GO:0006887 exocytosis 7/566 352/18722 0.910886455581396 0.936334911163328 CALM1/ANXA1/RAB25/ANXA3/SCIN/ATP6AP1/COPS5 7 GO:0007389 pattern specification process 9/566 436/18722 0.914136295558668 0.939119760465799 LRP2/ISL1/ADGRG1/SEMA3F/NRP1/ENG/GALNT11/LRP5/FOLR1 9 GO:0097696 receptor signaling pathway via STAT 3/566 181/18722 0.914228446059922 0.939119760465799 IL6ST/ISL1/PRLR 3 GO:0099504 synaptic vesicle cycle 3/566 181/18722 0.914228446059922 0.939119760465799 CALM1/ACTG1/CANX 3 GO:0098727 maintenance of cell number 2/566 134/18722 0.916109336385744 0.94083477868266 TPT1/LRP5 2 GO:0001960 negative regulation of cytokine-mediated signaling pathway 1/566 81/18722 0.917252908555902 0.941574809520608 GSTP1 1 GO:0008589 regulation of smoothened signaling pathway 1/566 81/18722 0.917252908555902 0.941574809520608 SERPINE2 1 GO:0045444 fat cell differentiation 4/566 229/18722 0.918663039136955 0.942804944729766 GPX1/BNIP3/LRP5/ADRB1 4 GO:0007032 endosome organization 1/566 82/18722 0.919765373217527 0.942842813864857 CHMP5 1 GO:0016575 histone deacetylation 1/566 82/18722 0.919765373217527 0.942842813864857 MORF4L2 1 GO:0043242 negative regulation of protein-containing complex disassembly 1/566 82/18722 0.919765373217527 0.942842813864857 SCIN 1 GO:0046364 monosaccharide biosynthetic process 1/566 82/18722 0.919765373217527 0.942842813864857 TPI1 1 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic 1/566 82/18722 0.919765373217527 0.942842813864857 RNASEH2A 1 GO:0072073 kidney epithelium development 2/566 136/18722 0.920182395831717 0.942842813864857 LAMA5/IQGAP1 2 GO:0099024 plasma membrane invagination 2/566 136/18722 0.920182395831717 0.942842813864857 ABCA1/AIF1 2 GO:0001510 RNA methylation 1/566 83/18722 0.922201682163819 0.944477085114636 TRMT112 1 GO:0051899 membrane depolarization 1/566 83/18722 0.922201682163819 0.944477085114636 PARK7 1 GO:0120032 regulation of plasma membrane bounded cell projection assembly 3/566 186/18722 0.923088990758744 0.945157187231473 PFN1/ARPC2/NRP1 3 GO:0001539 cilium or flagellum-dependent cell motility 2/566 138/18722 0.924068957774444 0.945157187231473 ATP2B4/DNAJA1 2 GO:0035107 appendage morphogenesis 2/566 138/18722 0.924068957774444 0.945157187231473 FBN2/LRP5 2 GO:0035108 limb morphogenesis 2/566 138/18722 0.924068957774444 0.945157187231473 FBN2/LRP5 2 GO:0060285 cilium-dependent cell motility 2/566 138/18722 0.924068957774444 0.945157187231473 ATP2B4/DNAJA1 2 GO:0002088 lens development in camera-type eye 1/566 84/18722 0.924564139800778 0.945157187231473 VIM 1 GO:0010660 regulation of muscle cell apoptotic process 1/566 84/18722 0.924564139800778 0.945157187231473 BNIP3 1 GO:0042440 pigment metabolic process 1/566 84/18722 0.924564139800778 0.945157187231473 GMPS 1 GO:0060491 regulation of cell projection assembly 3/566 188/18722 0.926392780662736 0.946629588226195 PFN1/ARPC2/NRP1 3 GO:0032259 methylation 7/566 364/18722 0.926641389465043 0.946629588226195 TYMS/TRMT112/SNRPB/SNRPD3/DPY30/PIH1D1/METTL7A 7 GO:0001656 metanephros development 1/566 85/18722 0.926854980924974 0.946629588226195 FBN1 1 GO:0060021 roof of mouth development 1/566 85/18722 0.926854980924974 0.946629588226195 ITGB8 1 GO:0022406 membrane docking 1/566 86/18722 0.929076372822622 0.948028423517376 CALM1 1 GO:0045921 positive regulation of exocytosis 1/566 86/18722 0.929076372822622 0.948028423517376 ATP6AP1 1 GO:0046928 regulation of neurotransmitter secretion 1/566 86/18722 0.929076372822622 0.948028423517376 CALM1 1 GO:0060761 negative regulation of response to cytokine stimulus 1/566 86/18722 0.929076372822622 0.948028423517376 GSTP1 1 GO:1901879 regulation of protein depolymerization 1/566 87/18722 0.931230417305472 0.949875462088372 SCIN 1 GO:0046467 membrane lipid biosynthetic process 2/566 142/18722 0.931313205753761 0.949875462088372 PLPP3/ASAH1 2 GO:0010324 membrane invagination 2/566 144/18722 0.934685563391234 0.953096685345345 ABCA1/AIF1 2 GO:0010657 muscle cell apoptotic process 1/566 89/18722 0.935344555689597 0.953550254621041 BNIP3 1 GO:0030705 cytoskeleton-dependent intracellular transport 3/566 195/18722 0.93695721292001 0.954975620860779 TUBA1B/TUBA1C/APP 3 GO:0061097 regulation of protein tyrosine kinase activity 1/566 90/18722 0.937308543317981 0.955115045743111 APP 1 GO:0003002 regionalization 6/566 331/18722 0.937661535838317 0.955256100126358 LRP2/ISL1/ADGRG1/SEMA3F/NRP1/LRP5 6 GO:0007043 cell-cell junction assembly 2/566 146/18722 0.937900773372896 0.955281226963197 ACTG1/GJA1 2 GO:0001657 ureteric bud development 1/566 91/18722 0.93921297464484 0.955961628513678 LAMA5 1 GO:0019935 cyclic-nucleotide-mediated signaling 1/566 91/18722 0.93921297464484 0.955961628513678 APOE 1 GO:0072080 nephron tubule development 1/566 91/18722 0.93921297464484 0.955961628513678 LAMA5 1 GO:0006497 protein lipidation 1/566 92/18722 0.941059652566101 0.956747561823312 ABCA1 1 GO:0032465 regulation of cytokinesis 1/566 92/18722 0.941059652566101 0.956747561823312 CALM1 1 GO:0072163 mesonephric epithelium development 1/566 92/18722 0.941059652566101 0.956747561823312 LAMA5 1 GO:0072164 mesonephric tubule development 1/566 92/18722 0.941059652566101 0.956747561823312 LAMA5 1 GO:1903351 cellular response to dopamine 1/566 92/18722 0.941059652566101 0.956747561823312 GNAI3 1 GO:0032088 negative regulation of NF-kappaB transcription factor activity 1/566 93/18722 0.942850325494044 0.957911832291074 TMSB4X 1 GO:0060993 kidney morphogenesis 1/566 93/18722 0.942850325494044 0.957911832291074 LAMA5 1 GO:1903350 response to dopamine 1/566 93/18722 0.942850325494044 0.957911832291074 GNAI3 1 GO:0048704 embryonic skeletal system morphogenesis 1/566 94/18722 0.944586689000962 0.959456979108438 EIF4A3 1 GO:0017157 regulation of exocytosis 3/566 202/18722 0.946106626493 0.960781638035319 CALM1/ANXA1/ATP6AP1 3 GO:0006644 phospholipid metabolic process 7/566 383/18722 0.946635740804935 0.961099730459195 APOC1/STOML2/IMPA2/PLPP3/HEXB/RAB38/SMG1 7 GO:0001823 mesonephros development 1/566 96/18722 0.947903015357923 0.961947623518001 LAMA5 1 GO:1904035 regulation of epithelial cell apoptotic process 1/566 96/18722 0.947903015357923 0.961947623518001 SERPINE1 1 GO:0030856 regulation of epithelial cell differentiation 2/566 154/18722 0.949320853481655 0.963115106619287 NME2/SERPINE1 2 GO:0035335 peptidyl-tyrosine dephosphorylation 1/566 97/18722 0.949486119261467 0.963115106619287 PTPRF 1 GO:0008654 phospholipid biosynthetic process 4/566 253/18722 0.949967962734303 0.963384366763808 IMPA2/HEXB/RAB38/SMG1 4 GO:0043473 pigmentation 1/566 98/18722 0.951021198804984 0.964232834679979 RAB38 1 GO:0007631 feeding behavior 1/566 99/18722 0.952509708334429 0.965302349534459 APP 1 GO:0021510 spinal cord development 1/566 99/18722 0.952509708334429 0.965302349534459 ISL1 1 GO:0006910 phagocytosis, recognition 1/566 100/18722 0.953953058228791 0.966545064914561 COLEC12 1 GO:0046486 glycerolipid metabolic process 7/566 392/18722 0.954292065783994 0.966668549913616 APOC1/APOE/GPX1/STOML2/IMPA2/RAB38/SMG1 7 GO:0046488 phosphatidylinositol metabolic process 2/566 159/18722 0.955410477680018 0.967581311790591 IMPA2/SMG1 2 GO:0046474 glycerophospholipid biosynthetic process 3/566 211/18722 0.956061033677889 0.968019950405722 IMPA2/RAB38/SMG1 3 GO:0006650 glycerophospholipid metabolic process 5/566 306/18722 0.956477575517265 0.968221502092511 APOC1/STOML2/IMPA2/RAB38/SMG1 5 GO:0034308 primary alcohol metabolic process 1/566 102/18722 0.956709708714803 0.968236331711367 PARK7 1 GO:0090305 nucleic acid phosphodiester bond hydrolysis 4/566 261/18722 0.957650404088641 0.968907330536971 NHP2/RNASEH2A/PLD3/EXOSC9 4 GO:0019233 sensory perception of pain 1/566 103/18722 0.958025621972989 0.968907330536971 MME 1 GO:0046425 regulation of receptor signaling pathway via JAK-STAT 1/566 103/18722 0.958025621972989 0.968907330536971 PRLR 1 GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway 1/566 104/18722 0.95930160338785 0.969757206694529 P2RY6 1 GO:0032006 regulation of TOR signaling 1/566 104/18722 0.95930160338785 0.969757206694529 PIH1D1 1 GO:0016079 synaptic vesicle exocytosis 1/566 105/18722 0.96053886262528 0.970787517913223 CALM1 1 GO:0019932 second-messenger-mediated signaling 5/566 312/18722 0.961305125551755 0.971341447788564 APOE/CALM1/ATP2B4/EGFR/GSTO1 5 GO:0006958 complement activation, classical pathway 1/566 108/18722 0.964029861799056 0.973870474690778 CD46 1 GO:0043414 macromolecule methylation 5/566 316/18722 0.964245519415307 0.973870474690778 TRMT112/SNRPB/SNRPD3/DPY30/PIH1D1 5 GO:1904659 glucose transmembrane transport 1/566 110/18722 0.966184164657561 0.975607144716594 SLC2A1 1 GO:0015718 monocarboxylic acid transport 1/566 111/18722 0.967212520707627 0.97642406852389 ANXA1 1 GO:0001578 microtubule bundle formation 1/566 113/18722 0.969176521244133 0.978184963178164 CLIP1 1 GO:0008645 hexose transmembrane transport 1/566 114/18722 0.970114029384056 0.978465713370598 SLC2A1 1 GO:0046660 female sex differentiation 1/566 114/18722 0.970114029384056 0.978465713370598 LRP2 1 GO:1904892 regulation of receptor signaling pathway via STAT 1/566 114/18722 0.970114029384056 0.978465713370598 PRLR 1 GO:0003341 cilium movement 2/566 175/18722 0.970537133096411 0.978670739874342 ATP2B4/DNAJA1 2 GO:0045055 regulated exocytosis 3/566 230/18722 0.971699054082488 0.979605814590899 CALM1/ANXA3/SCIN 3 GO:0015749 monosaccharide transmembrane transport 1/566 116/18722 0.971904511017072 0.979605814590899 SLC2A1 1 GO:0034219 carbohydrate transmembrane transport 1/566 118/18722 0.973587902251119 0.981080430244903 SLC2A1 1 GO:0002455 humoral immune response mediated by circulating immunoglobulin 1/566 121/18722 0.975926077757275 0.983214052540255 CD46 1 GO:0043433 negative regulation of DNA-binding transcription factor activity 2/566 185/18722 0.977334708003904 0.984410434396693 TMSB4X/SRI 2 GO:1902115 regulation of organelle assembly 2/566 186/18722 0.977924335365265 0.984781529302456 NPM1/CHMP5 2 GO:2000027 regulation of animal organ morphogenesis 1/566 125/18722 0.97872537703863 0.985365304969693 ZNRF3 1 GO:0033865 nucleoside bisphosphate metabolic process 1/566 128/18722 0.98060943607477 0.986592815684717 SLC26A2 1 GO:0033875 ribonucleoside bisphosphate metabolic process 1/566 128/18722 0.98060943607477 0.986592815684717 SLC26A2 1 GO:0034032 purine nucleoside bisphosphate metabolic process 1/566 128/18722 0.98060943607477 0.986592815684717 SLC26A2 1 GO:0006956 complement activation 1/566 130/18722 0.981771994463263 0.987539294927801 CD46 1 GO:0045017 glycerolipid biosynthetic process 3/566 252/18722 0.983219050655945 0.988771450987185 IMPA2/RAB38/SMG1 3 GO:0009581 detection of external stimulus 1/566 135/18722 0.984382982529176 0.989718391648575 SERPINE2 1 GO:1903305 regulation of regulated secretory pathway 1/566 136/18722 0.984858542430639 0.989972957981757 CALM1 1 GO:0034754 cellular hormone metabolic process 1/566 137/18722 0.985319645679549 0.989991763225719 SPP1 1 GO:0045165 cell fate commitment 3/566 258/18722 0.985480741566243 0.989991763225719 ISL1/NRP1/ITGB1 3 GO:0007224 smoothened signaling pathway 1/566 138/18722 0.985766730992725 0.989991763225719 SERPINE2 1 GO:0009582 detection of abiotic stimulus 1/566 138/18722 0.985766730992725 0.989991763225719 SERPINE2 1 GO:0045598 regulation of fat cell differentiation 1/566 139/18722 0.986200223796111 0.99020374297255 LRP5 1 GO:0007009 plasma membrane organization 1/566 142/18722 0.987423210400297 0.991090062587013 FOLR1 1 GO:0051607 defense response to virus 3/566 265/18722 0.987750810354577 0.991090062587013 IFITM2/BNIP3/HTRA1 3 GO:0140546 defense response to symbiont 3/566 265/18722 0.987750810354577 0.991090062587013 IFITM2/BNIP3/HTRA1 3 GO:0007269 neurotransmitter secretion 1/566 145/18722 0.988537985900705 0.991433005908975 CALM1 1 GO:0099643 signal release from synapse 1/566 145/18722 0.988537985900705 0.991433005908975 CALM1 1 GO:0007601 visual perception 2/566 215/18722 0.989815176943681 0.992490353097583 EFEMP1/TIMP3 2 GO:0008643 carbohydrate transport 1/566 152/18722 0.990770435213151 0.992864715834651 SLC2A1 1 GO:0050953 sensory perception of light stimulus 2/566 219/18722 0.990857576921239 0.992864715834651 EFEMP1/TIMP3 2 GO:0071805 potassium ion transmembrane transport 2/566 219/18722 0.990857576921239 0.992864715834651 ITGB1/AKAP9 2 GO:0010970 transport along microtubule 1/566 155/18722 0.991588947991364 0.993373986601609 APP 1 GO:0051650 establishment of vesicle localization 1/566 161/18722 0.993014963961639 0.994578767054492 TFG 1 GO:0006813 potassium ion transport 2/566 241/18722 0.994975862744493 0.996318610197589 ITGB1/AKAP9 2 GO:0051648 vesicle localization 1/566 177/18722 0.995745113581904 0.996864683082221 TFG 1 GO:0099111 microtubule-based transport 1/566 190/18722 0.997156629376395 0.998053352963964 APP 1 GO:0009952 anterior/posterior pattern specification 1/566 201/18722 0.997978782766128 0.998440823306308 LRP5 1 GO:0060271 cilium assembly 3/566 337/18722 0.997992287446781 0.998440823306308 DYNLL1/LAMA5/GALNT11 3 GO:0044782 cilium organization 3/566 368/18722 0.999103597228755 0.999328064448982 DYNLL1/LAMA5/GALNT11 3 GO:0007018 microtubule-based movement 3/566 382/18722 0.999380011951334 0.999380011951334 ATP2B4/DNAJA1/APP 3